Dyall, Kenneth G.
1992-01-01
The effect of omission of two-electron integrals involving basis functions for the small component of the wavefunction on the eigenvalue spectrum in the Dirac-Hartree-Fock problem is studied. From an analysis of the Fock matrix it is shown that omission of these integrals moves the negative-energy states down, not up. Their complete omission does not give rise to intruder states. The appearance of intruder states occurs when only some of the core integrals are omitted, due to the nature of particular contraction schemes used for the core basis functions. Use of radially localized functions rather than atomic functions alleviates the intruder state problem.
On the Beebe-Linderberg two-electron integral approximation
Røeggen, I.; Wisløff-Nilssen, E.
1986-12-01
The Beebe-Linderberg two-electron integral approximation, which is generated by a Cholesky decomposition of the two-electron integral matrix ([μν|λσ]), is slightly modified. On the basis of test calculations, two key questions concerning this approximation are discussed: The numerical rank of the two-electron integral matrix and the relationship between the integral threshold and electronic properties. The numerical results presented in this work suggest that the modified Beebe-Linderberg approximation might be considered as an alternative to effective core potential methods.
Atomic-batched tensor decomposed two-electron repulsion integrals
Schmitz, Gunnar; Madsen, Niels Kristian; Christiansen, Ove
2017-04-01
We present a new integral format for 4-index electron repulsion integrals, in which several strategies like the Resolution-of-the-Identity (RI) approximation and other more general tensor-decomposition techniques are combined with an atomic batching scheme. The 3-index RI integral tensor is divided into sub-tensors defined by atom pairs on which we perform an accelerated decomposition to the canonical product (CP) format. In a first step, the RI integrals are decomposed to a high-rank CP-like format by repeated singular value decompositions followed by a rank reduction, which uses a Tucker decomposition as an intermediate step to lower the prefactor of the algorithm. After decomposing the RI sub-tensors (within the Coulomb metric), they can be reassembled to the full decomposed tensor (RC approach) or the atomic batched format can be maintained (ABC approach). In the first case, the integrals are very similar to the well-known tensor hypercontraction integral format, which gained some attraction in recent years since it allows for quartic scaling implementations of MP2 and some coupled cluster methods. On the MP2 level, the RC and ABC approaches are compared concerning efficiency and storage requirements. Furthermore, the overall accuracy of this approach is assessed. Initial test calculations show a good accuracy and that it is not limited to small systems.
Benchmark values for molecular two-electron integrals arising from the Dirac equation
Baǧcı, A.; Hoggan, P. E.
2015-02-01
The two-center two-electron Coulomb and hybrid integrals arising in relativistic and nonrelativistic ab initio calculations on molecules are evaluated. Compact, arbitrarily accurate expressions are obtained. They are expressed through molecular auxiliary functions and evaluated with the numerical Global-adaptive method for arbitrary values of parameters in the noninteger Slater-type orbitals. Highly accurate benchmark values are presented for these integrals. The convergence properties of new molecular auxiliary functions are investigated. The comparison for two-center two-electron integrals is made with results obtained from single center expansions by translation of the wave function to a single center with integer principal quantum numbers and results obtained from the Cuba numerical integration algorithm, respectively. The procedures discussed in this work are capable of yielding highly accurate two-center two-electron integrals for all ranges of orbital parameters.
Benchmark values for molecular two-electron integrals arising from the Dirac equation.
Bağcı, A; Hoggan, P E
2015-02-01
The two-center two-electron Coulomb and hybrid integrals arising in relativistic and nonrelativistic ab initio calculations on molecules are evaluated. Compact, arbitrarily accurate expressions are obtained. They are expressed through molecular auxiliary functions and evaluated with the numerical Global-adaptive method for arbitrary values of parameters in the noninteger Slater-type orbitals. Highly accurate benchmark values are presented for these integrals. The convergence properties of new molecular auxiliary functions are investigated. The comparison for two-center two-electron integrals is made with results obtained from single center expansions by translation of the wave function to a single center with integer principal quantum numbers and results obtained from the Cuba numerical integration algorithm, respectively. The procedures discussed in this work are capable of yielding highly accurate two-center two-electron integrals for all ranges of orbital parameters.
Analytic derivatives for the Cholesky representation of the two-electron integrals.
Aquilante, Francesco; Lindh, Roland; Pedersen, Thomas Bondo
2008-07-21
We propose a formalism for calculating analytic derivatives of the electronic energy with respect to nuclear coordinates using Cholesky decomposition of the two-electron integrals. The formalism is derived by exploiting the equivalence of Cholesky decomposition and density fitting when a suitable auxiliary basis set is used for expanding atomic orbital product densities in the latter. An implementation of gradients at the nonhybrid density functional theory level is presented, and sample calculations demonstrate that the errors in equilibrium geometries due to the Cholesky representation of the integrals can be controlled by adjusting the decomposition threshold.
Fast calculation of two-electron-repulsion integrals: a numerical approach
Lopes, Pedro E M
2016-01-01
An alternative methodology to evaluate two-electron-repulsion integrals based on numerical approximation is proposed. Computational chemistry has branched into two major fields with methodologies based on quantum mechanics and classical force fields. However, there are significant shadowy areas not covered by any of the available methods. Many relevant systems are often too big for traditional quantum chemical methods while being chemically too complex for classical force fields. Examples include systems in nanomedicine, studies of metalloproteins, etc. There is an urgent need to develop fast quantum chemical methods able to study large and complex systems. This work is a proof-of-concept on the numerical techniques required to develop accurate and computationally efficient algorithms for the fast calculation of electron-repulsion integrals, one of the most significant bottlenecks in the extension of quantum chemistry to large systems. All concepts and calculations were developed for the three-center integral...
Peng, Bo; Kowalski, Karol
2017-09-12
The representation and storage of two-electron integral tensors are vital in large-scale applications of accurate electronic structure methods. Low-rank representation and efficient storage strategy of integral tensors can significantly reduce the numerical overhead and consequently time-to-solution of these methods. In this work, by combining pivoted incomplete Cholesky decomposition (CD) with a follow-up truncated singular vector decomposition (SVD), we develop a decomposition strategy to approximately represent the two-electron integral tensor in terms of low-rank vectors. A systematic benchmark test on a series of 1-D, 2-D, and 3-D carbon-hydrogen systems demonstrates high efficiency and scalability of the compound two-step decomposition of the two-electron integral tensor in our implementation. For the size of the atomic basis set, Nb, ranging from ∼100 up to ∼2,000, the observed numerical scaling of our implementation shows [Formula: see text] versus [Formula: see text] cost of performing single CD on the two-electron integral tensor in most of the other implementations. More importantly, this decomposition strategy can significantly reduce the storage requirement of the atomic orbital (AO) two-electron integral tensor from [Formula: see text] to [Formula: see text] with moderate decomposition thresholds. The accuracy tests have been performed using ground- and excited-state formulations of coupled cluster formalism employing single and double excitations (CCSD) on several benchmark systems including the C60 molecule described by nearly 1,400 basis functions. The results show that the decomposition thresholds can be generally set to 10(-4) to 10(-3) to give acceptable compromise between efficiency and accuracy.
Fossgård, Eirik; Ruud, Kenneth
2006-02-01
We describe the implementation of a parallel, in-core, integral-direct Hartree-Fock and density functional theory code for the efficient calculation of Hartree-Fock wave functions and density functional theory. The algorithm is based on a parallel master-slave algorithm, and the two-electron integrals calculated by a slave are stored in available local memory. To ensure the greatest computational savings, the master node keeps track of all integral batches stored on the different slaves. The code can reuse undifferentiated two-electron integrals both in the wave function optimization and in the evaluation of second-, third-, and fourth-order molecular properties. Superlinear scaling is achieved in a series of test examples, with speedups of up to 55 achieved for calculations run on medium-sized molecules on 16 processors with respect to the time used on a single processor.
Evaluation of Two-center One- and Two-electron Integrals over Slater Type Orbitals
Institute of Scientific and Technical Information of China (English)
YAKAR Yusuf; (O)ZMEN Ayhan; ATAV (U)lfet
2006-01-01
A formulation previously presented by the authors for coulomb integrals was generalized to other two-center integrals, except exchange integral. Within this frame, molecular integrals were expressed in terms of some new functions closely related to the well-known incomplete gamma functions and these functions recursively evaluated.Special issues arising in the case of hybrid integrals were addressed, and the results were compared with the ones found in the literature.
Institute of Scientific and Technical Information of China (English)
CAI Liang; ZHANG Ping; YANG Tao; PAN Xiao-Yin
2011-01-01
By using the path integral approach, we investigate the problem of Hooke's atom (two electrons interacting with Coulomb potential in an external harmonic-oscillator potential) in an arbitrary time-dependent electric field. For a certain infinite set of discrete oscillator frequencies, we obtain the analytical solutions. The ground state polarization of the atom is then calculated. The same result is also obtained through linear response theory.
Simulations of one- and two-electron systems by Bead-Fourier path integral molecular dynamics
Ivanov, Sergei D.; Lyubartsev, Alexander P.
2005-07-01
The Bead-Fourier path integral molecular dynamics technique introduced earlier [S. D. Ivanov, A. P. Lyubartsev, and A. Laaksonen, Phys. Rev. E 67 066710 (2003)] is applied for simulation of electrons in the simplest molecules: molecular hydrogen, helium atom, and their ions. Special attention is paid to the correct description of electrons in the core region of a nucleus. In an attempt to smooth the Coulomb potential at small distances, a recipe is suggested. The simulation results are in excellent agreement with the analytical solution for the "harmonic helium atom", as well as with the vibrational potential of the H2 molecule and He ionization energies. It is demonstrated, that the Bead-Fourier path integral molecular dynamics technique is able to provide the accuracy required for the description of electron structure and chemical bonds in cases when electron exchange effects need not be taken into account.
Lesiuk, Michał
2014-01-01
In this paper, which constitutes the first part of the series, we consider calculation of two-centre Coulomb and hybrid integrals over Slater-type orbitals (STOs). General formulae for these integrals are derived with no restrictions on the values of the quantum numbers and nonlinear parameters. Direct integration over the coordinates of one of the electrons leaves us with the set of overlap-like integrals which are evaluated by using two distinct methods. The first one is based on the transformation to the ellipsoidal coordinates system and the second utilises a recursive scheme for consecutive increase of the angular momenta in the integrand. In both methods simple one-dimensional numerical integrations are used in order to avoid severe digital erosion connected with the straightforward use of the alternative analytical formulae. It is discussed that the numerical integration does not introduce a large computational overhead since the integrands are well-behaved functions, calculated recursively with decent...
Li, Rongbao; Bianchet, Mario A.; Talalay, Paul; Amzel, L. Mario
1995-09-01
Quinone reductase [NAD(P)H:(quinone acceptor) oxidoreductase, EC 1.6.99.2], also called DT diaphorase, is a homodimeric FAD-containing enzyme that catalyzes obligatory NAD(P)H-dependent two-electron reductions of quinones and protects cells against the toxic and neoplastic effects of free radicals and reactive oxygen species arising from one-electron reductions. These two-electron reductions participate in the reductive bioactivation of cancer chemotherapeutic agents such as mitomycin C in tumor cells. Thus, surprisingly, the same enzymatic reaction that protects normal cells activates cytotoxic drugs used in cancer chemotherapy. The 2.1-Å crystal structure of rat liver quinone reductase reveals that the folding of a portion of each monomer is similar to that of flavodoxin, a bacterial FMN-containing protein. Two additional portions of the polypeptide chains are involved in dimerization and in formation of the two identical catalytic sites to which both monomers contribute. The crystallographic structures of two FAD-containing enzyme complexes (one containing NADP^+, the other containing duroquinone) suggest that direct hydride transfers from NAD(P)H to FAD and from FADH_2 to the quinone [which occupies the site vacated by NAD(P)H] provide a simple rationale for the obligatory two-electron reductions involving a ping-pong mechanism.
Chu, John C K; Dalton, Derek M; Rovis, Tomislav
2015-04-08
We report a catalytic asymmetric synthesis of piperidines through [4 + 2] cycloaddition of 1-azadienes and nitro-alkenes. The reaction uses earth abundant Zn as catalyst and is highly diastereo- and regioselective. A novel BOPA ligand (F-BOPA) confers high reactivity and enantioselectivity in the process. The presence of ortho substitution on the arenes adjacent to the bis(oxazolines) was found to be particularly impactful, due to limiting the undesired coordination of 1-azadiene to the Lewis acid and thus allowing the reaction to be carried out at lower temperature. A series of secondary kinetic isotope effect studies using a range of ligands implicates a stepwise mechanism for the transformation, involving an initial Michael-type addition of the imine to the nitro-alkene followed by a cyclization event. The stepwise mechanism obviates the electronic requirement inherent to a concerted mechanism, explaining the successful cycloaddition between two electron-deficient partners.
Energy Technology Data Exchange (ETDEWEB)
Hoy, Erik P.; Mazziotti, David A., E-mail: damazz@uchicago.edu [Department of Chemistry and The James Franck Institute, The University of Chicago, Chicago, Illinois 60637 (United States)
2015-08-14
Tensor factorization of the 2-electron integral matrix is a well-known technique for reducing the computational scaling of ab initio electronic structure methods toward that of Hartree-Fock and density functional theories. The simplest factorization that maintains the positive semidefinite character of the 2-electron integral matrix is the Cholesky factorization. In this paper, we introduce a family of positive semidefinite factorizations that generalize the Cholesky factorization. Using an implementation of the factorization within the parametric 2-RDM method [D. A. Mazziotti, Phys. Rev. Lett. 101, 253002 (2008)], we study several inorganic molecules, alkane chains, and potential energy curves and find that this generalized factorization retains the accuracy and size extensivity of the Cholesky factorization, even in the presence of multi-reference correlation. The generalized family of positive semidefinite factorizations has potential applications to low-scaling ab initio electronic structure methods that treat electron correlation with a computational cost approaching that of the Hartree-Fock method or density functional theory.
Hoy, Erik P; Mazziotti, David A
2015-08-14
Tensor factorization of the 2-electron integral matrix is a well-known technique for reducing the computational scaling of ab initio electronic structure methods toward that of Hartree-Fock and density functional theories. The simplest factorization that maintains the positive semidefinite character of the 2-electron integral matrix is the Cholesky factorization. In this paper, we introduce a family of positive semidefinite factorizations that generalize the Cholesky factorization. Using an implementation of the factorization within the parametric 2-RDM method [D. A. Mazziotti, Phys. Rev. Lett. 101, 253002 (2008)], we study several inorganic molecules, alkane chains, and potential energy curves and find that this generalized factorization retains the accuracy and size extensivity of the Cholesky factorization, even in the presence of multi-reference correlation. The generalized family of positive semidefinite factorizations has potential applications to low-scaling ab initio electronic structure methods that treat electron correlation with a computational cost approaching that of the Hartree-Fock method or density functional theory.
Two-Electron Transfer Pathways.
Lin, Jiaxing; Balamurugan, D; Zhang, Peng; Skourtis, Spiros S; Beratan, David N
2015-06-18
The frontiers of electron-transfer chemistry demand that we develop theoretical frameworks to describe the delivery of multiple electrons, atoms, and ions in molecular systems. When electrons move over long distances through high barriers, where the probability for thermal population of oxidized or reduced bridge-localized states is very small, the electrons will tunnel from the donor (D) to acceptor (A), facilitated by bridge-mediated superexchange interactions. If the stable donor and acceptor redox states on D and A differ by two electrons, it is possible that the electrons will propagate coherently from D to A. While structure-function relations for single-electron superexchange in molecules are well established, strategies to manipulate the coherent flow of multiple electrons are largely unknown. In contrast to one-electron superexchange, two-electron superexchange involves both one- and two-electron virtual intermediate states, the number of virtual intermediates increases very rapidly with system size, and multiple classes of pathways interfere with one another. In the study described here, we developed simple superexchange models for two-electron transfer. We explored how the bridge structure and energetics influence multielectron superexchange, and we compared two-electron superexchange interactions to single-electron superexchange. Multielectron superexchange introduces interference between singly and doubly oxidized (or reduced) bridge virtual states, so that even simple linear donor-bridge-acceptor systems have pathway topologies that resemble those seen for one-electron superexchange through bridges with multiple parallel pathways. The simple model systems studied here exhibit a richness that is amenable to experimental exploration by manipulating the multiple pathways, pathway crosstalk, and changes in the number of donor and acceptor species. The features that emerge from these studies may assist in developing new strategies to deliver multiple
Buried Waste Integrated Demonstration stakeholder involvement model
Energy Technology Data Exchange (ETDEWEB)
Kaupanger, R.M.; Kostelnik, K.M.; Milam, L.M.
1994-04-01
The Buried Waste Integrated Demonstration (BWID) is a program funded by the US Department of Energy (DOE) Office of Technology Development. BWID supports the applied research, development, demonstration, and evaluation of a suite of advanced technologies that together form a comprehensive remediation system for the effective and efficient remediation of buried waste. Stakeholder participation in the DOE Environmental Management decision-making process is critical to remediation efforts. Appropriate mechanisms for communication with the public, private sector, regulators, elected officials, and others are being aggressively pursued by BWID to permit informed participation. This document summarizes public outreach efforts during FY-93 and presents a strategy for expanded stakeholder involvement during FY-94.
Generalized Hermite-Hadamard type inequalities involving fractional integral operators.
Set, Erhan; Noor, Muhammed Aslam; Awan, Muhammed Uzair; Gözpinar, Abdurrahman
2017-01-01
In this article, a new general integral identity involving generalized fractional integral operators is established. With the help of this identity new Hermite-Hadamard type inequalities are obtained for functions whose absolute values of derivatives are convex. As a consequence, the main results of this paper generalize the existing Hermite-Hadamard type inequalities involving the Riemann-Liouville fractional integral.
Weighted hardy type integral inequalities involving many functions
Directory of Open Access Journals (Sweden)
Sabir Hussain
2012-06-01
Full Text Available The object of this paper is to derive some new weighted Hardy type integral inequalities involving many functions and to obtain a classical weighted Hardy type inequality involving many functions.
An integral involving the generalized zeta function
Directory of Open Access Journals (Sweden)
E. Elizalde
1990-01-01
Full Text Available A general value for ∫abdtlogΓ(t, for a, b positive reals, is derived in terms of the Hurwitz ζ function. That expression is checked for a previously known special integral, and the case where a is a positive integer and b is half an odd integer is considered. The result finds application in calculating the numerical value of the derivative of the Riemann zeta function at the point −1, a quantity that arises in the evaluation of determinants of Laplacians on compact Riemann surfaces.
PROBLEM WITH INTEGRAL BOUNDARY CONDITIONS INVOLVING PETTIS INTEGRAL
Institute of Scientific and Technical Information of China (English)
Hussein A.H. Salem
2011-01-01
In this article, we investigate the existence of Pseudo solutions for some frac- tional order boundary value problem with integral boundary conditions in the Banach space of continuous function equipped with its weak topology. The class of such problems constitute a very interesting and important class of problems. They include two, three, multi-point and nonlocal boundary-value problems as special cases. In our investigation, the right hand side of the above problem is assumed to be Pettis integrable function. To encompass the full scope of this article, we give an example illustrating the main result.
DUAL INTEGRAL EQUATIONS INVOLVING LEGENDRE FUNCTIONS IN DISTRIBUTION SPACES
Directory of Open Access Journals (Sweden)
P. K. BANERJI, DESHNA LOONKER
2010-11-01
Full Text Available In this paper we use the Mehler-Fock transformation to obtain thesolution of dual integral equations involving Legendre functions. The solutionso obtained is proved to be distributional because they satisfy properties ofdistribution space.
Some integrals involving generalized k-Struve functions
Directory of Open Access Journals (Sweden)
Kottakkaran Sooppy Nisar
2017-03-01
Full Text Available The close form of some integrals involving recently developed generalized k-Struve functions is obtained. The outcome of these integrations is expressed in terms of generalized Wright functions. Several special cases are deduced which lead to some known results.
Gravitational force between two electrons in superconductors
de Matos, Clovis Jacinto
2007-01-01
The attractive gravitational force between two electrons in superconductors is deduced from the Eddington-Dirac large number relation, together with Beck and Mackey electromagnetic model of vacuum energy in superconductors. This force is estimated to be weaker than the gravitational attraction between two electrons in the vacuum.
Certain Inequalities Involving the Fractional q-Integral Operators
Directory of Open Access Journals (Sweden)
Dumitru Baleanu
2014-01-01
Full Text Available We establish some inequalities involving Saigo fractional q-integral operator in the theory of quantum calculus by using the two parameters of deformation, q1 and q2, whose special cases are shown to yield corresponding inequalities associated with Riemann-Liouville and Kober fractional q-integral operators, respectively. Furthermore, we also consider their relevance with other related known results.
Effects of top management involvement in integrated marketing communications
Directory of Open Access Journals (Sweden)
Nina Hočevar
2007-12-01
Full Text Available There is scarce empirical evidence in the academic literature of how top management involvement influences the degree of integrated marketing communications. At the same time, some authors believe that this relationship should be explored more extensively.In this paper we present one possible approach to investigating the relationship between top management involvement and the degree of integrated marketing communications. Our research established that a greater involvement of top management in marketing communications could be associated with a higher degree of IMC. Investigating the relationship between management and IMC is indeed at a very early stage. We suggest that this study has provided a basis for future research on the relationship between top management involvement in marketing communications and the degree of IMC.
Integrated Transport Planning Framework Involving Combined Utility Regret Approach
DEFF Research Database (Denmark)
Wang, Yang; Monzon, Andres; Di Ciommo, Floridea;
2014-01-01
Sustainable transport planning requires an integrated approach involving strategic planning, impact analysis, and multicriteria evaluation. This study aimed at relaxing the utility-based decision-making assumption by newly embedding anticipated-regret and combined utility regret decision mechanisms...... in a framework for integrated transport planning. The framework consisted of a two-round Delphi survey, integrated land use and transport model for Madrid, and multicriteria analysis. Results show that (a) the regret-based ranking has a similar mean but larger variance than the utility-based ranking does, (b...
Two-electron photoionization of endohedral atoms
Amusia, M Ya; Mandelzweig, V B
2006-01-01
Using $He@C_{60}$ as an example, we demonstrate that static potential of the fullerene core essentially alters the cross section of the two-electron ionization differential in one-electron energy $d\\sigma ^{++}(\\omega )/d\\epsilon $. We found that at high photon energy prominent oscillations appear in it due to reflection of the second, slow electron wave on the $% C_{60}$ shell, which "dies out" at relatively high $\\epsilon $ values, of about 2$\\div $3 two-electron ionization potentials. The results were presented for ratios $R_{C_{60}}(\\omega ,\\epsilon)\\equiv d\\sigma ^{++}(\\omega ,\\epsilon)/d\\sigma ^{a++}(\\omega,\\epsilon)$, where $d\\sigma ^{a++}(\\omega,\\epsilon)/d\\epsilon$ is the two-electron differential photoionization cross section. We have calculated the ratio $R_{i,ful}= \\sigma_{i} ^{++}(\\omega)/\\sigma_{i}^{a++}(\\omega)$, that accounts for reflection of both photoelectrons by the $C_{60}$ shell. We have calculated also the value of two-electron photoionization cross section $\\sigma ^{++}(\\omega)$ and fo...
Patient involvement in the safety of care: an integrative review
Directory of Open Access Journals (Sweden)
Thaynara de Oliveira Silva
2016-06-01
Full Text Available The aim of this integrative review was to survey the strategies adopted by health institutions that involve patients in care as a barrier to prevent incidents. A search was conducted in MEDLINE, LILACS, CINAHL and PubMed databases using the descriptors ‘patient safety’, ‘iatrogenic’, ‘medical error’ and ‘involvement’. The review included studies in full text published between 2003 and March 2016 in English, Spanish or Portuguese. It was found that the effective communication and the development of patients’ autonomy are the most advocated strategies. The level of evidence of studies was limited to four and six. The assessment or description of institutional practices involving patients in their safety emerged as a gap in scientific knowledge. The impact of this review is to demonstrate the need for randomized studies to identify effective interventions, directing health institutions towards change in the organizational culture, focusing on safety and patient-centered care.
Auluck, S K H
2010-01-01
Spectral decomposition of dynamical equations using curl-eigenfunctions has been extensively used in fluid and plasma dynamics problems using their orthogonality and completeness properties for both linear and non-linear cases. Coefficients of such expansions are integrals over products of Bessel functions in problems involving cylindrical geometry. In this paper, certain identities involving products of two and three general solutions of Bessel's equation have been derived. Some of these identities have been useful in the study of Turner relaxation of annular magnetized plasma [S.K.H. Auluck, Phys. Plasmas, 16, 122504, 2009], where quadratic integral quantities such as helicity and total energy were expressed as algebraic functions of the arbitrary constants of the general solution of Bessel's equation, allowing their determination by a minimization procedure. Identities involving products of three solutions enable expanding a product of two solutions in a Fourier-Bessel series of single Bessel functions fac...
Double ionization of two-electron systems
Energy Technology Data Exchange (ETDEWEB)
Ancarani, L U; Cappello, C Dal [Laboratoire de Physique Moleculaire et des Collisions, Universite Paul Verlaine - Metz, 57078 Metz (France); Gasaneo, G, E-mail: ancarani@univ-metz.f [Departamento de Fisica, Universidad Nacional del Sur and Consejo Nacional de Investigaciones CientIficas y Tecnicas, 8000 BahIa Blanca, Buenos Aires (Argentina)
2010-02-01
We address various issues related to the double ionization by electron impact of two-electron systems. The emphasis will be put on the theoretical description of high incident energy (e,3e) processes, for which the first Born approximation should be suitable. In the case of helium, absolute experimental data for fivefold differential cross sections are available in coplanar geometry. We will review and discuss the divergencies existing between the results obtained with different theoretical models, and those appearing when compared to the experiments in particular with respect to the absolute scale. We will then discuss some results obtained in a recently proposed out of plane geometry.
Dissipative two-electron transfer: A numerical renormalization group study
Tornow, Sabine; Bulla, Ralf; Anders, Frithjof B.; Nitzan, Abraham
2008-07-01
We investigate nonequilibrium two-electron transfer in a model redox system represented by a two-site extended Hubbard model and embedded in a dissipative environment. The influence of the electron-electron interactions and the coupling to a dissipative bosonic bath on the electron transfer is studied in different temperature regimes. At high temperatures, Marcus transfer rates are evaluated, and at low temperatures, we calculate equilibrium and nonequilibrium population probabilities of the donor and acceptor with the nonperturbative numerical renormalization group approach. We obtain the nonequilibrium dynamics of the system prepared in an initial state of two electrons at the donor site and identify conditions under which the electron transfer involves one concerted two-electron step or two sequential single-electron steps. The rates of the sequential transfer depend nonmonotonically on the difference between the intersite and on-site Coulomb interaction, which become renormalized in the presence of the bosonic bath. If this difference is much larger than the hopping matrix element, the temperature as well as the reorganization energy, simultaneous transfer of both electrons between donor and acceptor can be observed.
Involving stakeholders in building integrated fisheries models using Bayesian methods.
Haapasaari, Päivi; Mäntyniemi, Samu; Kuikka, Sakari
2013-06-01
A participatory Bayesian approach was used to investigate how the views of stakeholders could be utilized to develop models to help understand the Central Baltic herring fishery. In task one, we applied the Bayesian belief network methodology to elicit the causal assumptions of six stakeholders on factors that influence natural mortality, growth, and egg survival of the herring stock in probabilistic terms. We also integrated the expressed views into a meta-model using the Bayesian model averaging (BMA) method. In task two, we used influence diagrams to study qualitatively how the stakeholders frame the management problem of the herring fishery and elucidate what kind of causalities the different views involve. The paper combines these two tasks to assess the suitability of the methodological choices to participatory modeling in terms of both a modeling tool and participation mode. The paper also assesses the potential of the study to contribute to the development of participatory modeling practices. It is concluded that the subjective perspective to knowledge, that is fundamental in Bayesian theory, suits participatory modeling better than a positivist paradigm that seeks the objective truth. The methodology provides a flexible tool that can be adapted to different kinds of needs and challenges of participatory modeling. The ability of the approach to deal with small data sets makes it cost-effective in participatory contexts. However, the BMA methodology used in modeling the biological uncertainties is so complex that it needs further development before it can be introduced to wider use in participatory contexts.
Involving Stakeholders in Building Integrated Fisheries Models Using Bayesian Methods
Haapasaari, Päivi; Mäntyniemi, Samu; Kuikka, Sakari
2013-06-01
A participatory Bayesian approach was used to investigate how the views of stakeholders could be utilized to develop models to help understand the Central Baltic herring fishery. In task one, we applied the Bayesian belief network methodology to elicit the causal assumptions of six stakeholders on factors that influence natural mortality, growth, and egg survival of the herring stock in probabilistic terms. We also integrated the expressed views into a meta-model using the Bayesian model averaging (BMA) method. In task two, we used influence diagrams to study qualitatively how the stakeholders frame the management problem of the herring fishery and elucidate what kind of causalities the different views involve. The paper combines these two tasks to assess the suitability of the methodological choices to participatory modeling in terms of both a modeling tool and participation mode. The paper also assesses the potential of the study to contribute to the development of participatory modeling practices. It is concluded that the subjective perspective to knowledge, that is fundamental in Bayesian theory, suits participatory modeling better than a positivist paradigm that seeks the objective truth. The methodology provides a flexible tool that can be adapted to different kinds of needs and challenges of participatory modeling. The ability of the approach to deal with small data sets makes it cost-effective in participatory contexts. However, the BMA methodology used in modeling the biological uncertainties is so complex that it needs further development before it can be introduced to wider use in participatory contexts.
Generalizing Integrals Involving X [superscript X] and Series Involving N [superscript N
Osler, Thomas J.; Tsay, Jeffrey
2005-01-01
In this paper, the authors evaluate the series and integrals presented by P. Glaister. The authors show that this function has the Maclauren series expansion. The authors derive the series from the integral in two ways. The first derivation uses the technique employed by Glaister. The second derivation uses a change in variable in the integral.
Integral relations of optical characteristics involving pairs of condensed medium
Sakhnovskyj, Mykhajlo Y.; Tymochko, Bogdan M.; Rudeichuk, Volodymyr M.; Dominikov, Mickolay M.
2015-11-01
The integral relations among optical invariants and elipsometric parameters of light are obtained in this paper. It is shown, that among optical invariants there is an integral relation, similar to Kramers-Kronig relation for complex dielectric conductivity or a complex index of refraction. The possibility to determine the spectral values of conductivity through the integral transform of optical invariants or ellipsometric angles is discussed.
A unified approach to several results involving integrals of multifunctions
Balder, E.J.
2001-01-01
A well-known equivalence of randomization result of Wald and Wolfowitz states that any Young measure can be regarded as a probability measure on the set of all measurable functions. Here we give a sucient condition for the Young measure to be equivalent to a probability measure on the set of all integrable selectors of a given multifunction. In this way, Aumann's identity for integrals of multifunctions can be interpreted in a novel fashion. By additionally applying a fundamental result from ...
Further Generalized Integrals Involving x[superscript x] and Series Involving N[superscript N
Glaister, P.
2005-01-01
In this paper, the author gives a further simple generalization of a power series evaluation of an integral using Taylor series to derive the result. The author encourages readers to consider numerical methods to evaluate the integrals and sums. Such methods are suitable for use in courses in advanced calculus and numerical analysis.
User Involvement as a Configurable Integrated Product Delivery
DEFF Research Database (Denmark)
Vibæk, Kasper Sánchez
2009-01-01
Integrated product deliveries as known from the product industry are beginning to emerge in construction. These are normally considered as physical systems that can be configured and customised for a specific delivery to form part of a unique construction project and help to reduce the complexity...... physical systems could however become architecturally intriguing by leaving more open the solution space of the final result.......Integrated product deliveries as known from the product industry are beginning to emerge in construction. These are normally considered as physical systems that can be configured and customised for a specific delivery to form part of a unique construction project and help to reduce the complexity...... as a configurable integrated product delivery then the architect can – using slightly provocatively a term from the production industry – be seen a configuration manager of processes shaping our physical surroundings. Products focusing on standardisation and mass customisation of the building process rather than...
On a new class of integrals involving Bessel functions of the first kind
Directory of Open Access Journals (Sweden)
P. Agarwal
2014-06-01
Full Text Available In recent years, several integral formulas involving a variety of special functions have been developed by many authors. Also many integral formulas containing the Bessel function $J_\
School Integration Efforts Three Years after "Parents Involved"
Tefera, Adai; Siegel-Hawley, Genevieve; Frankenberg, Erica
2010-01-01
This report synthesizes major themes in local policymaking during the last year, as local school districts continue to grapple with legal and economic constraints on policies that are aimed at creating diverse schools. The report last year on the second anniversary of "Parents Involved" began to uncover some of the consequences of the difficult…
A note on dual integral equations involving inverse associated Weber-Orr transforms
Directory of Open Access Journals (Sweden)
Nanigopal Mandal
1996-01-01
Full Text Available We consider dual integral equations involving inverse associated Weber-Orr transforms. Elementary methods have been used to reduce dual integral equations to a Fredholm integral equation of second kind. Some known results are obtained as special case.
Second-Order Integrals for Systems in E2 Involving Spin
Directory of Open Access Journals (Sweden)
İsmet Yurduşen
2015-01-01
Full Text Available In two-dimensional Euclidean plane, existence of second-order integrals of motion is investigated for integrable Hamiltonian systems involving spin (e.g., those systems describing interaction between two particles with spin 0 and spin 1/2 and it has been shown that no nontrivial second-order integrals of motion exist for such systems.
Some remarks on the two-electron atom
Apostol, M
1996-01-01
New, approximate, two-electron wavefunctions are introduced for the two-electron atoms (cations), which account remarkably well for the ground-state energies and the lowest-excxited states (where available). A new scheme of electronic configurations is also proposed for the multi-electron atoms.
A Tale of Two Electrons: Correlation at High Density
Loos, Pierre-François
2010-01-01
We review our recent progress in the determination of the high-density correlation energy $\\Ec$ in two-electron systems. Several two-electron systems are considered, such as the well known helium-like ions (helium), and the Hooke's law atom (hookium). We also present results regarding two electrons on the surface of a sphere (spherium), and two electrons trapped in a spherical box (ballium). We also show that, in the large-dimension limit, the high-density correlation energy of two opposite-spin electrons interacting {\\em via} a Coulomb potential is given by $\\Ec \\sim -1/(8D^2)$ for any radial external potential $V(r)$, where $D$ is the dimensionality of the space. This result explains the similarity of $\\Ec$ in the previous two-electron systems for $D=3$.
Nontrivial Solution of Fractional Differential System Involving Riemann-Stieltjes Integral Condition
Directory of Open Access Journals (Sweden)
Ge-Feng Yang
2012-01-01
differential system involving the Riemann-Stieltjes integral condition, by using the Leray-Schauder nonlinear alternative and the Banach contraction mapping principle, some sufficient conditions of the existence and uniqueness of a nontrivial solution of a system are obtained.
Expansion of a class of functions into an integral involving associated Legendre functions
Directory of Open Access Journals (Sweden)
Nanigopal Mandal
1994-01-01
Full Text Available A theorem for expansion of a class of functions into an integral involving associated Legendre functions is obtained in this paper. This is a somewhat general integral expansion formula for a function f(x defined in (x1,x2 where -1
Natural occupation numbers in two-electron quantum rings
Energy Technology Data Exchange (ETDEWEB)
Tognetti, Vincent, E-mail: vincent.tognetti@univ-rouen.fr [Normandy Univ., COBRA UMR 6014 & FR 3038, Université de Rouen, INSA Rouen, CNRS, 1 rue Tesniére, 76821 Mont Saint Aignan, Cedex (France); Loos, Pierre-François [Research School of Chemistry, Australian National University, Canberra ACT 2601 (Australia)
2016-02-07
Natural orbitals (NOs) are central constituents for evaluating correlation energies through efficient approximations. Here, we report the closed-form expression of the NOs of two-electron quantum rings, which are prototypical finite-extension systems and new starting points for the development of exchange-correlation functionals in density functional theory. We also show that the natural occupation numbers for these two-electron paradigms are in general non-vanishing and follow the same power law decay as atomic and molecular two-electron systems.
Natural occupation numbers in two-electron quantum rings
Tognetti, Vincent; Loos, Pierre-François
2016-02-01
Natural orbitals (NOs) are central constituents for evaluating correlation energies through efficient approximations. Here, we report the closed-form expression of the NOs of two-electron quantum rings, which are prototypical finite-extension systems and new starting points for the development of exchange-correlation functionals in density functional theory. We also show that the natural occupation numbers for these two-electron paradigms are in general non-vanishing and follow the same power law decay as atomic and molecular two-electron systems.
Natural occupation numbers in two-electron quantum rings.
Tognetti, Vincent; Loos, Pierre-François
2016-02-07
Natural orbitals (NOs) are central constituents for evaluating correlation energies through efficient approximations. Here, we report the closed-form expression of the NOs of two-electron quantum rings, which are prototypical finite-extension systems and new starting points for the development of exchange-correlation functionals in density functional theory. We also show that the natural occupation numbers for these two-electron paradigms are in general non-vanishing and follow the same power law decay as atomic and molecular two-electron systems.
Applying GG-Convex Function to Hermite-Hadamard Inequalities Involving Hadamard Fractional Integrals
Directory of Open Access Journals (Sweden)
Zhi Zhang
2014-01-01
Full Text Available By virtue of fractional integral identities, incomplete beta function, useful series, and inequalities, we apply the concept of GG-convex function to derive new type Hermite-Hadamard inequalities involving Hadamard fractional integrals. Finally, some applications to special means of real numbers are demonstrated.
African regional integration and European involvement: external agents in the East African Community
Bachmann, V.; Sidaway, J.D.
2010-01-01
The EU's role as a model for regional integration is widely discussed in scholarship and policy circles. The promotion of regional integration is central to the EU's external relations and is frequently expected by the EU's partners. This paper examines European involvement with the East African
Semi-Implicit Algorithm for Elastoplastic Damage Models Involving Energy Integration
Ji Zhang; Jie Li
2016-01-01
This study aims to develop a semi-implicit constitutive integration algorithm for a class of elastoplastic damage models where calculation of damage energy release rates involves integration of free energy. The constitutive equations with energy integration are split into the elastic predictor, plastic corrector, and damage corrector. The plastic corrector is solved with an improved format of the semi-implicit spectral return mapping, which is characterized by constant flow direction and plas...
Certain Fractional Integral Formulas Involving the Product of Generalized Bessel Functions
Baleanu, D.; Agarwal, P.; Purohit, S. D.
2013-01-01
We apply generalized operators of fractional integration involving Appell's function F 3(·) due to Marichev-Saigo-Maeda, to the product of the generalized Bessel function of the first kind due to Baricz. The results are expressed in terms of the multivariable generalized Lauricella functions. Corresponding assertions in terms of Saigo, Erdélyi-Kober, Riemann-Liouville, and Weyl type of fractional integrals are also presented. Some interesting special cases of our two main results are presented. We also point out that the results presented here, being of general character, are easily reducible to yield many diverse new and known integral formulas involving simpler functions. PMID:24379745
Directory of Open Access Journals (Sweden)
Rui Li
2013-01-01
Full Text Available We study the existence and uniqueness of the positive solution for the fractional differential system involving the Riemann-Stieltjes integral boundary conditions , , , , , and , where , , and and are the standard Riemann-Liouville derivatives, and are functions of bounded variation, and and denote the Riemann-Stieltjes integral. Our results are based on a generalized fixed point theorem for weakly contractive mappings in partially ordered sets.
Majorana solutions to the two-electron problem
Esposito, S
2012-01-01
A review of the known different methods and results devised to study the two-electron atom problem, appeared in the early years of quantum mechanics, is given, with particular reference to the calculations of the ground state energy of helium. This is supplemented by several, unpublished results obtained around the same years by Ettore Majorana, which results did not convey in his published papers on the argument, and thus remained unknown until now. Particularly interesting, even for current research in atomic and nuclear physics, is a general variant of the variational method, developed by Majorana in order to take directly into account, already in the trial wavefunction, the action of the full Hamiltonian operator of a given quantum system. Moreover, notable calculations specialized to the study of the two-electron problem show the introduction of the remarkable concept of an effective nuclear charge different for the two electrons (thus generalizing previous known results), and an application of the pertu...
Two-electron quantum ring in short pulses
Institute of Scientific and Technical Information of China (English)
Poonam Silotia; Rakesh Kumar Meena; Vinod Prasad
2015-01-01
The response of two-electron quantum ring system to the short laser pulses of different shapes in the presence of external static electric field is studied. The variation of transition probabilities of the two-electron quatum ring from ground state to excited states with a number of parameters is shown and explained. The energy levels and wavefunctions of the system in the presence of static electric field are found by solving the time-independent Schr ¨odinger equation numerically by finite difference method. The shape of the pulse plays a dominant role on the dynamics.
Attosecond-correlated dynamics of two electrons in argon
Indian Academy of Sciences (India)
V Sharma; N Camus; B Fischer; M Kremer; A Rudenko; B Bergues; M Kuebel; N G Johnson; M F Kling; T Pfeifer; J Ullrich; R Moshammer
2014-01-01
In this work we explored strong field-induced decay of doubly excited transient Coulomb complex Ar** → Ar2++2. We measured the correlated two-electron emission as a function of carrier envelop phase (CEP) of 6 fs pulses in the non-sequential double ionization (NSDI) of argon. Classical model calculations suggest that the intermediate doubly excited Coulomb complex loses memory of its formation dynamics. We estimated the ionization time difference between the two electrons from NSDI of argon and it is 200 ± 100 as (N Camus et al, Phys. Rev. Lett. 108, 073003 (2012)).
Students' Involvement in Social Networking and Attitudes towards Its Integration into Teaching
Umoh, Ukeme Ekpedeme; Etuk, Etuk Nssien
2016-01-01
The study examined Students' Involvement in Social Networking and attitudes towards its Integration into Teaching. The study was carried out in the University of Uyo, Akwa Ibom State, Nigeria. The population of the study consisted of 17,618 undergraduate students enrolled into full time degree programmes in the University of Uyo for 2014/2015…
Governing integration through sports. A case study of civil society involvement in welfare policy
DEFF Research Database (Denmark)
Agergaard, Sine; Michelsen la Cour, Annette
2012-01-01
governing techniques of the welfare state. To do so, a case study approach is applied. First of all, the article will describe the ways in which the issues of enhancing ethnic integration through sports is represented (thought of as a problem) by the involved public authorities and non-state actors using...
DEFF Research Database (Denmark)
Franchin, P.; Ditlevsen, Ove Dalager; Kiureghian, Armen Der
2002-01-01
The model correction factor method (MCFM) is used in conjunction with the first-order reliability method (FORM) to solve structural reliability problems involving integrals of non-Gaussian random fields. The approach replaces the limit-state function with an idealized one, in which the integrals...... are considered to be Gaussian. Conventional FORM analysis yields the linearization point of the idealized limit-state surface. A model correction factor is then introduced to push the idealized limit-state surface onto the actual limit-state surface. A few iterations yield a good approximation of the reliability...... reliability method; Model correction factor method; Nataf field integration; Non-Gaussion random field; Random field integration; Structural reliability; Pile foundation reliability...
Integrative analysis for finding genes and networks involved in diabetes and other complex diseases
DEFF Research Database (Denmark)
Bergholdt, R.; Størling, Zenia, Marian; Hansen, Kasper Lage;
2007-01-01
identified a number of new protein network modules and novel candidate genes/proteins for type 1 diabetes. We propose this type of integrative analysis as a general method for the elucidation of genes and networks involved in diabetes and other complex diseases.......We have developed an integrative analysis method combining genetic interactions, identified using type 1 diabetes genome scan data, and a high-confidence human protein interaction network. Resulting networks were ranked by the significance of the enrichment of proteins from interacting regions. We...
Directory of Open Access Journals (Sweden)
Obidjon Kh. Abdullaev
2016-06-01
Full Text Available In this work, we study the existence and uniqueness of solutions to non-local boundary value problems with integral gluing condition. Mixed type equations (parabolic-hyperbolic involving the Caputo fractional derivative have loaded parts in Riemann-Liouville integrals. Thus we use the method of integral energy to prove uniqueness, and the method of integral equations to prove existence.
Excitations and benchmark ensemble density functional theory for two electrons
Pribram-Jones, Aurora; Trail, John R; Burke, Kieron; Needs, Richard J; Ullrich, Carsten A
2014-01-01
A new method for extracting ensemble Kohn-Sham potentials from accurate excited state densities is applied to a variety of two electron systems, exploring the behavior of exact ensemble density functional theory. The issue of separating the Hartree energy and the choice of degenerate eigenstates is explored. A new approximation, spin eigenstate Hartree-exchange (SEHX), is derived. Exact conditions that are proven include the signs of the correlation energy components, the virial theorem for both exchange and correlation, and the asymptotic behavior of the potential for small weights of the excited states. Many energy components are given as a function of the weights for two electrons in a one-dimensional flat box, in a box with a large barrier to create charge transfer excitations, in a three-dimensional harmonic well (Hooke's atom), and for the He atom singlet-triplet ensemble, singlet-triplet-singlet ensemble, and triplet bi-ensemble.
Excitations and benchmark ensemble density functional theory for two electrons
Energy Technology Data Exchange (ETDEWEB)
Pribram-Jones, Aurora; Burke, Kieron [Department of Chemistry, University of California-Irvine, Irvine, California 92697 (United States); Yang, Zeng-hui; Ullrich, Carsten A. [Department of Physics and Astronomy, University of Missouri, Columbia, Missouri 65211 (United States); Trail, John R.; Needs, Richard J. [Theory of Condensed Matter Group, Cavendish Laboratory, University of Cambridge, Cambridge CB3 0HE (United Kingdom)
2014-05-14
A new method for extracting ensemble Kohn-Sham potentials from accurate excited state densities is applied to a variety of two-electron systems, exploring the behavior of exact ensemble density functional theory. The issue of separating the Hartree energy and the choice of degenerate eigenstates is explored. A new approximation, spin eigenstate Hartree-exchange, is derived. Exact conditions that are proven include the signs of the correlation energy components and the asymptotic behavior of the potential for small weights of the excited states. Many energy components are given as a function of the weights for two electrons in a one-dimensional flat box, in a box with a large barrier to create charge transfer excitations, in a three-dimensional harmonic well (Hooke's atom), and for the He atom singlet-triplet ensemble, singlet-triplet-singlet ensemble, and triplet bi-ensemble.
CMS: Simulated Higgs to two jets and two electrons
1997-01-01
This track is an example of simulated data modelled for the CMS detector on the Large Hadron Collider (LHC) at CERN, which will begin taking data in 2008. Here a Higgs boson is produced which decays into two jets of hadrons and two electrons. The lines represent the possible paths of particles produced by the proton-proton collision in the detector while the energy these particles deposit is shown in blue.
Quantum Transport in Solids: Two-Electron Processes.
1995-06-01
The central objective of this research program has been to study theoretically the underlying principles of quantum transport in solids. The area of...research investigated has emphasized the understanding of two electron processes in quantum transport . The problems have been treated analytically to...the extent possible through the use of dynamical localized Wannier functions. These results have been and are being incorporated in a full quantum
Fourier transform technique in variational treatment of two-electron parabolic quantum dot
Institute of Scientific and Technical Information of China (English)
S.(S)akiro(g)lu; A.Yildiz; (U).Dogan; K.Akgüng(o)r; H.Epik; Y.Ergün; H.Sarl; I.S(o)kmen
2009-01-01
In this work,we propose an efficient method of reducing the computational effort of variational calculation with a Hylleraas-like trial wavefunction.The method consists of introducing integral transforms for the terms as r12k exp (-λr12)which provide the calculation of the expectation value of energy and the relevant matrix elements to be done analytically over single-electron coordinates instead of Hylleraas coordinates.We have used this method to calculate the ground state energy of a two-electron system in a spherical dot and a disk-like quantum dot separately.Under parabolic confinement potential and within effective mass approximation size and shape effects of quantum dots on the ground state energy of two electrons have been investigated.The calculation shows that our results even with a small number of basis states axe in good agreement with previous theoretical results.
Institute of Scientific and Technical Information of China (English)
无
2007-01-01
Cellular responses rely on signal perception and integration. A nice example of this is self incompatibility (SI), which is an important mechanism to prevent inbreeding. It prevents self-fertilization by using a highly discriminatory cellular recognition and rejection mechanism. Most S1 systems are genetically specified by the S-locus, which has a pollen and a pistil S-component. A receptor-ligand interaction is used by Papaver rhoeas to control SI. S proteins encoded by the pistil part of the S-locus interact with incompatible pollen to achieve rapid inhibition of tip growth. The incompatible SI interaction triggers a Ca2+ -dependent signaling cascade. A number of SI-specific events are triggered in incompatible pollen, including rapid depolymerization of the actin cytoskeleton; phosphorylation of soluble inorganic pyrophosphatases (SPPases), Prp26.1; activation of a mitogen activated protein kinase, p56; programmed cell death (PCD) involving a caspase-3-like activlty. These events contribute to prevent self-fertilization. We are attempting to establish the functional signiflcance of these events, and their possible involvement in integrating a coordinated signaling response. Here we describe the identification of these components shown to be involved in SI, together with recent progress in identifying links between some of them. These data constitute the first steps in elucidating how SI signaling is integrated.
Integrating social science knowledge into natural resource management public involvement practice
DEFF Research Database (Denmark)
Stummann, Cathy Brown
This PhD study explores the long-recognized challenge of integrating social science knowledge into NRM public involvement practice theoretically and empirically. Theoretically, the study draws on research from adult learning, continuing rofessional education and professional knowledge development...... to better understand how social science knowledge can benefit NRM public involvement practice. Empirically, the study explores the potential of NRM continuing professional education as a means for introducing social science knowledge to public NRM professionals. The study finds social science knowledge can...... be of value to NRM public involvement prospectively and retrospectively; and that continuing professional education can be an effective means to introducing social science knowledge to public NRM professionals. In the design of NRM continuing professional education focused on social science knowledge...
Langston, Anne L; McCallum, Marilyn; Campbell, Marion K; Robertson, Clare; Ralston, Stuart H
2005-01-01
Although, consumer involvement in individual studies is often limited, their involvement in guiding health research is generally considered to be beneficial. This paper outlines our experiences of an integrated relationship between the organisers of a clinical trial and a consumer organisation. The PRISM trial is a UK multicentre, randomized controlled trial comparing treatment strategies for Paget's disease of the bone. The National Association for the Relief of Paget's Disease (NARPD) is the only UK support group for sufferers of Paget's disease and has worked closely with the PRISM team from the outset. NARPD involvement is integral to the conduct of the trial and specific roles have included: peer-review; trial steering committee membership; provision of advice to participants, and promotion of the trial amongst Paget's disease patients. The integrated relationship has yielded benefits to both the trial and the consumer organisation. The benefits for the trial have included: recruitment of participants via NARPD contacts; well-informed participants; unsolicited patient advocacy of the trial; and interested and pro-active collaborators. For the NARPD and Paget's disease sufferers, benefits have included: increased awareness of Paget's disease; increased access to relevant health research; increased awareness of the NARPD services; and wider transfer of diagnosis and management knowledge to/from health care professionals. Our experience has shown that an integrated approach between a trial team and a consumer organisation is worthwhile. Adoption of such an approach in other trials may yield significant improvements in recruitment and quality of participant information flow. There are, however, resource implications for both parties.
2010-10-01
... ACQUISITIONS OF CONTROL Safety Integration Plans § 244.15 Subjects to be addressed in a Safety Integration Plan... 49 Transportation 4 2010-10-01 2010-10-01 false Subjects to be addressed in a Safety Integration Plan not involving an amalgamation of operations. 244.15 Section 244.15 Transportation...
Dynamics of two-electron excitations in helium
Energy Technology Data Exchange (ETDEWEB)
Caldwell, C.D.; Menzel, A.; Frigo, S.P. [Univ. of Central Florida, Orlando, FL (United States)] [and others
1997-04-01
Excitation of both electrons in helium offers a unique window for studying electron correlation at the most basic level in an atom in which these two electrons and the nucleus form a three-body system. The authors utilized the first light available at the U-8 undulator-SGM monochromator beamline to investigate the dynamic parameters, partial cross sections, differential cross sections, and photoelectron angular distribution parameters ({beta}), with a high resolving power for the photon beam and at the highly differential level afforded by the use of their electron spectrometer. In parallel, they carried out detailed calculations of the relevant properties by a theoretical approach that is based on the hyperspherical close-coupling method. Partial photoionization cross sections {sigma}{sub n}, and photoelectron angular distributions {beta}{sub n} were measured for all possible final ionic states He{sup +}(n) in the region of the double excitations N(K,T){sup A} up to the N=5 threshold. At a photon energy bandpass of 12 meV below the thresholds N=3, 4, and 5, this level of differentiation offers the most critical assessment of the dynamics of the two-electron excitations to date. The experimental data were seen to be very well described by the most advanced theoretical calculations.
DEFF Research Database (Denmark)
Mansouri, Seyed Soheil; Sales-Cruz, Mauricio; Huusom, Jakob Kjøbsted
2016-01-01
In this work, integrated process design and control of reactive distillation processes that involve multiple elements (more than two) is addressed through a computer-aided hierarchical decomposition-based framework. Multiple elements are encountered for reactive systems when four or more compounds...... (including inert compounds) are encountered. The reactive distillation design methods and tools which are similar in concept to design of binary non-reactive distillations and binary reactive distillations are used for design of multi-element reactive distillation processes, such as driving force approach...
Magnetic alteration of entanglement in two-electron quantum dots
Simonovic, N S
2015-01-01
Quantum entanglement is analyzed thoroughly in the case of the ground and lowest states of two-electron axially symmetric quantum dots under a perpendicular magnetic field. The individual-particle and the center-of-mass representations are used to study the entanglement variation at the transition from interacting to noninteracting particle regimes. The mechanism of symmetry breaking due to the interaction, that results in the states with symmetries related to the later representation only, being entangled even at the vanishing interaction, is discussed. The analytical expression for the entanglement measure based on the linear entropy is derived in the limit of noninteracting electrons. It reproduces remarkably well the numerical results for the lowest states with the magnetic quantum number M>2 in the interacting regime. It is found that the entanglement of the ground state is a discontinuous function of the field strength. A method to estimate the entanglement of the ground state, characterized by the quan...
Frustrated double ionization in two-electron triatomic molecules
Chen, A.; Price, H.; Staudte, A.; Emmanouilidou, A.
2016-10-01
Using a semiclassical model, we investigate frustrated double ionization (FDI) in D3+ , a two-electron triatomic molecule, when driven by an intense, linearly polarized, near-infrared (800 nm) laser field. We compute the kinetic energy release of the nuclei and find a good agreement between experiment and our model. We explore the two pathways of FDI and show that, with increasing field strength, over-the-barrier ionization overtakes tunnel ionization as the underlying mechanism of FDI. Moreover, we compute the angular distribution of the ion fragments for FDI and identify a feature that can potentially be observed experimentally and is a signature of only one of the two pathways of FDI.
Frustrated double ionization in two-electron triatomic molecules
Chen, A; Staudte, A; Emmanouilidou, A
2016-01-01
Using a semi-classical model, we investigate frustrated double ionization (FDI) in $\\mathrm{D_3^+}$, a two-electron triatomic molecule, when driven by an intense, linearly polarized, near-infrared (800 nm) laser field. We do so using a semi-classical model. We find a good agreement between experiment and our model. We explore the two pathways of FDI and show that, with increasing field strength, over-the-barrier ionization overtakes tunnel ionization as the underlying mechanism of FDI. Moreover, we compute the angular distribution of the ion fragments for FDI and identify a feature that can be observed experimentally and that is a signature of only one of the two pathways of FDI.
Semi-Implicit Algorithm for Elastoplastic Damage Models Involving Energy Integration
Directory of Open Access Journals (Sweden)
Ji Zhang
2016-01-01
Full Text Available This study aims to develop a semi-implicit constitutive integration algorithm for a class of elastoplastic damage models where calculation of damage energy release rates involves integration of free energy. The constitutive equations with energy integration are split into the elastic predictor, plastic corrector, and damage corrector. The plastic corrector is solved with an improved format of the semi-implicit spectral return mapping, which is characterized by constant flow direction and plastic moduli calculated at initial yield, enforcement of consistency at the end, and coordinate-independent formulation with an orthogonally similar stress tensor. The tangent stiffness consistent with the updating algorithm is derived. The algorithm is implemented with a recently proposed elastoplastic damage model for concrete, and several typical mechanical tests of reinforced concrete components are simulated. The present semi-implicit algorithm proves to achieve a balance between accuracy, stability, and efficiency compared with the implicit and explicit algorithms and calculate free energy accurately with small time steps.
Double ionization in R -matrix theory using a two-electron outer region
Wragg, Jack; Parker, J. S.; van der Hart, H. W.
2015-08-01
We have developed a two-electron outer region for use within R -matrix theory to describe double ionization processes. The capability of this method is demonstrated for single-photon double ionization of He in the photon energy region between 80 and 180 eV. The cross sections are in agreement with established data. The extended R -matrix with time dependence method also provides information on higher-order processes, as demonstrated by the identification of signatures for sequential double ionization processes involving an intermediate He+ state with n =2 .
Flood Induced Disasters and Stakeholder Involvement to Implement Integrated Food Management in Nepal
Gautam, N. P.
2016-12-01
Nepal, a landlocked country in South Asia covers an area of 147, 181 square kilometers. Its elevation ranges from 61m as the lowest to 8848m, the highest peak Everest in the world. More than 80% of the annual rainfall occurs in the monsoon season from June to September. Thus, due to the intense rainfall that occurs within a short period, monsoon acts as the biggest cause for the occurrence of different disastrous events including flood. Beyond it, Nepal lies at the center and southern edge of Hindu-Kush Himalayan (HKH) region, which is the youngest geological formation in the world. Hence, floods and landslides are common in this region. In Nepal, from the records of 1971-2010, floods and landslides are the second biggest cause for casualties after epidemics. Hawaii based Center of Excellence in disaster management and humanitarian assistance in 2015 has declared Nepal as 30th vulnerable country from the aspect of floods. According to WMO definition, integrated flood management (IFM) is a process of promoting an integrated rather than a fragmented approach to flood management, integrating land and water resource development in a river basin within the context of integrated water resources management (IWRM), with the aim of maximizing the net benefits from flood plains while minimizing loss of life from flooding. That is the reason why the IFM is one of the important countermeasures to be implemented in Nepal to reduce the adverse effects of floods. This study emphasizes on the existing conditions along with the challenges of IFM with respect to stakeholder involvement in the context of Nepal. It can be assured that all the highlighted issues coming out from this study will be highly valuable to policy makers, implementing agencies along with scientific and local communities to enhance IFM works in the nation for the benefits of societies.
Complex dynamics in planar two-electron quantum dots
Energy Technology Data Exchange (ETDEWEB)
Schroeter, Sebastian Josef Arthur
2013-06-25
Quantum dots play an important role in a wide range of recent experimental and technological developments. In particular they are promising candidates for realisations of quantum bits and further applications in quantum information theory. The harmonically confined Hooke's atom model is experimentally verified and separates in centre-of-mass and relative coordinates. Findings that are contradictory to this separability call for an extension of the model, in particular changing the confinement potential. In order to study effects of an anharmonic confinement potential on spectral properties of planar two-electron quantum dots a sophisticated numerical approach is developed. Comparison between the Helium atom, Hooke's atom and an anharmonic potential model are undertaken in order to improve the description of quantum dots. Classical and quantum features of complexity and chaos are investigated and used to characterise the dynamics of the system to be mixed regular-chaotic. Influence of decoherence can be described by quantum fidelity, which measures the effect of a perturbation on the time evolution. The quantum fidelity of eigenstates of the system depends strongly on the properties of the perturbation. Several methods for solving the time-dependent Schrödinger equation are implemented and a high level of accuracy for long time evolutions is achieved. The concept of offset entanglement, the entanglement of harmonic models in the noninteracting limit, is introduced. This concept explains different questions raised in the literature for harmonic quantum dot models, recently. It shows that only in the groundstate the electrons are not entangled in the fermionic sense. The applicability, validity, and origin of Hund's first rule in general quantum dot models is further addressed. In fact Hund's first rule is only applicable, and in this case also valid, for one pair of singlet and triplet states in Hooke's atom. For more realistic models of two-electron
Directory of Open Access Journals (Sweden)
Oxman Andrew D
2006-12-01
should also be explicit. If differences in values are likely to affect a decision, such that people in different setting would likely make different choices about interventions or actions based on differences in their values, global recommendations should be explicit in terms of which values were applied and allow for adaptation after incorporating local values. How should WHO ensure that appropriate values are integrated in recommendations? • All WHO guideline groups should uniformly apply explicit, transparent and clearly described methods for integrating values. • WHO should consider involving relevant stakeholders if this is feasible and efficient. • WHO should develop a checklist for guidelines panels to help them to ensure that ethical considerations relevant to recommendations are addressed explicitly and transparently. How should users and consumers be involved in generating recommendations? • Including consumers in groups that are making global recommendations presents major challenges with respect to the impossibility of including a representative spectrum of consumers from a variety of cultures and settings. Nonetheless, consideration should be given to including consumers in groups who are able to challenge assumptions that are made about the values used for making recommendations, rather than represent the values of consumers around the world. • WHO should establish a network to facilitate involvement of users. • Draft recommendations should be reviewed by consumers, who should be asked explicitly to consider the values that were used. How should values be presented in recommendations? • Recommendations should include a description of how decisions were made about the relative importance of the consequences (benefits, harms and costs of a decision. • Values that influence recommendations should be reported along with the research evidence underlying recommendations. • When differences in values would lead to different decisions or there is
Controlling autoionization in strontium two-electron-excited states
Fields, Robert; Zhang, Xinyue; Dunning, F. Barry; Yoshida, Shuhei; Burgdörfer, Joachim
2016-05-01
One challenge in engineering long-lived two-electron-excited states, i.e., so-called planetary atoms, is autoionization. Autoionization, however, can be suppressed if the outermost electron is placed in a high- n, n ~ 300 - 600 , high- L state because such states have only a very small overlap with the inner electron, even when this is also excited to a state of relatively high n and hence of relatively long lifetime. Here the L-dependence of the autoionization rate for high- n strontium Rydberg atoms is examined during excitation of the core ion 5 s 2S1 / 2 - 5 p 2P3 / 2 transition. Measurements in which the angular momentum of the Rydberg electron is controlled using a pulsed electric field show that the autoionization rate decreases rapidly with increasing L and becomes very small for values larger than ~ 20 . The data are analyzed with the aid of calculations undertaken using complex scaling. Research supported by the NSF and Robert A. Welch Foundation.
Directory of Open Access Journals (Sweden)
Prashant Jindal
2016-06-01
Full Text Available For the past four decades the integrated vendor and buyer supply chain inventory model has been an interesting topic, but quality improvement of defective items in the integrated inventory model with backorder price discount involving controllable lead time has been rarely discussed. The aim of this paper is to minimize the total related cost in the continuous review model by considering the order quantity, reorder point, lead time, process quality, backorder price discount and number of shipment as decision variables. Moreover, we assume that an investment function is used to improve the process quality. The lead time demand follows a normal distribution. In addition, the buyer offers backorder price discount to motivate the customers for possible backorders. There are some defective items in the arrival lot, so its treatment is also taken in account in this paper. We develop an iterative procedure for finding the optimal values of decision variables and numerical example is presented to illustrate the solution procedure. Additionally, sensitivity analysis with respect to major parameters is also carried out.
Greven, Inez M; Ramsey, Richard
2017-02-01
The majority of human neuroscience research has focussed on understanding functional organisation within segregated patches of cortex. The ventral visual stream has been associated with the detection of physical features such as faces and body parts, whereas the theory-of-mind network has been associated with making inferences about mental states and underlying character, such as whether someone is friendly, selfish, or generous. To date, however, it is largely unknown how such distinct processing components integrate neural signals. Using functional magnetic resonance imaging and connectivity analyses, we investigated the contribution of functional integration to social perception. During scanning, participants observed bodies that had previously been associated with trait-based or neutral information. Additionally, we independently localised the body perception and theory-of-mind networks. We demonstrate that when observing someone who cues the recall of stored social knowledge compared to non-social knowledge, a node in the ventral visual stream (extrastriate body area) shows greater coupling with part of the theory-of-mind network (temporal pole). These results show that functional connections provide an interface between perceptual and inferential processing components, thus providing neurobiological evidence that supports the view that understanding the visual environment involves interplay between conceptual knowledge and perceptual processing. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.
Observation of coherent population trapping in a V-type two-electron system
Singh, Alok K
2015-01-01
We observe coherent population trapping (CPT) in a two-electron atom---$^{174}$Yb---using the $\\rm {^1S_0,F=0} \\rightarrow {^3P_1,F'=1}$ transition. CPT is not possible for such a transition according to one-electron theory because the magnetic sublevels form a V-type system, but in a two-electron atom like Yb, the interaction of the electrons transforms the level structure into a $ \\Lambda $-type system, which allows the formation of a dark state and hence the observation of CPT. Since the two levels involved are degenerate, we use a magnetic field to lift the degeneracy. The single fluorescence dip then splits into five dips---the central unshifted one corresponds to coherent population oscillation, while the outer four are due to CPT. The linewidth of the CPT resonance is about 300 kHz and is limited by the natural linewidth of the excited state, which is to be expected because the excited state is involved in the formation of the dark state.
Lawson, Hal; Briar-Lawson, Katharine
This report describes the outcomes of research that investigated school reform, school-linked services, parent involvement, and community school programs in schools in 36 states. Results found that services were often added on to school sites without any intent to integrate them with school reform; teachers were not directly involved in services;…
Nonrelativistic structure calculations of two-electron ions in a strongly coupled plasma environment
Energy Technology Data Exchange (ETDEWEB)
Bhattacharyya, S.; Saha, J. K.; Mukherjee, T. K.
2015-04-01
In this work, the controversy between the interpretations of recent measurements on dense aluminum plasma created with the Linac coherent light source (LCLS) x-ray free electron laser (FEL) and the Orion laser has been addressed. In both kinds of experiments, heliumlike and hydrogenlike spectral lines are used for plasma diagnostics. However, there exist no precise theoretical calculations for He-like ions within a dense plasma environment. The strong need for an accurate theoretical estimate for spectral properties of He-like ions in a strongly coupled plasma environment leads us to perform ab initio calculations in the framework of the Rayleigh-Ritz variation principle in Hylleraas coordinates where an ion-sphere potential is used. An approach to resolve the long-drawn problem of numerical instability for evaluating two-electron integrals with an extended basis inside a finite domain is presented here. The present values of electron densities corresponding to the disappearance of different spectral lines obtained within the framework of an ion-sphere potential show excellent agreement with Orion laser experiments in Al plasma and with recent theories. Moreover, this method is extended to predict the critical plasma densities at which the spectral lines of H-like and He-like carbon and argon ions disappear. Incidental degeneracy and level-crossing phenomena are being reported for two-electron ions embedded in strongly coupled plasma. Thermodynamic pressure experienced by the ions in their respective ground states inside the ion spheres is also reported.
Morgan-Brown, Theron; Jacobson, Susan K; Wald, Kenneth; Child, Brian
2010-04-01
Scientific understanding of the role of development in conservation has been hindered by the quality of evaluations of integrated conservation and development projects. We used a quasi-experimental design to quantitatively assess a conservation and development project involving commercial butterfly farming in the East Usambara Mountains of Tanzania. Using a survey of conservation attitudes, beliefs, knowledge, and behavior, we compared 150 butterfly farmers with a control group of 170 fellow community members. Due to the nonrandom assignment of individuals to the two groups, we used propensity-score matching and weighting in our analyses to control for observed bias. Eighty percent of the farmers believed butterfly farming would be impossible if local forests were cleared, and butterfly farmers reported significantly more participation in forest conservation behaviors and were more likely to believe that conservation behaviors were effective. The two groups did not differ in terms of their general conservation attitudes, attitudes toward conservation officials, or knowledge of conservation-friendly building techniques. The relationship between butterfly farming and conservation behavior was mediated by dependency on butterfly farming income. Assuming unobserved bias played a limited role, our findings suggest that participation in butterfly farming increased participation in conservation behaviors among project participants because farmers perceive a link between earnings from butterfly farming and forest conservation.
Ab-initio calculations on two-electron ions in strongly coupled plasma environment
Bhattacharyya, S; Mukherjee, T K
2015-01-01
In this work, the controversy between the interpretations of recent measurements on dense aluminum plasma created with Linac coherent light sources (LCLS) X-ray free electron laser (FEL) and Orion laser has been addressed. In both kind of experiments, helium-like and hydrogen-like spectral lines are used for plasma diagnostics . However, there exist no precise theoretical calculations for He-like ions within dense plasma environment. The strong need for an accurate theoretical estimates for spectral properties of He-like ions in strongly coupled plasma environment leads us to perform ab initio calculations in the framework of Rayleigh-Ritz variation principle in Hylleraas coordinates where ion-sphere potential is used. An approach to resolve the long-drawn problem of numerical instability for evaluating two-electron integrals with extended basis inside a finite domain is presented here. The present values of electron densities corresponding to disappearance of different spectral lines obtained within the fram...
On the elastostatic significance of four boundary integrals involving biharmonic functions
DEFF Research Database (Denmark)
Christiansen, Søren
1998-01-01
of the four integrals and we find that it is related to the displacements of the elastic material: Single valued displacements are obtained provided that three of the integrals are zero. (The fourth integral does not provide further information.) It is already known from the classical literature that two...... of the integrals are related to single valued displacements, but the elastostatical significance of the third integral seems to be a new result. The method of investigation is unconventional: For "all possible" biharmonic functions, in polar coordinates, we determine stresses, strains, displacements etc. together...
James, Christopher A.; Hill, Howard M.
2007-01-01
This article describes procedural elements involved in ensuring the integrity of bioanalytical data. These elements can be divided into 3 areas. First, there are those ensuring the integrity of the analyte until analysis, through correct sample collection, handling, shipment, and storage procedures. Incorrect procedures can lead to loss of analyte via instability, addition of analyte through contamination or instability of related metabolites, or changes in the matrix composition that may adv...
Institute of Scientific and Technical Information of China (English)
MA Qinghua; YANG Enhao
2000-01-01
An estimation method for solutions to the general linear system of Volterratype integral inequalities containing several iterated integral functionals is obtained. This method is based on a result proved by the present second author in Journ. Math. Anal. Appl.(1984). A certain two-dimensional system of nonlinear ordinary differential equations is also discussed to demonstrate the usefulness of our method.
Wolf-Wendel, Lisa; Ward, Kelly; Kinzie, Jillian
2009-01-01
Established theories and constructs long associated with student success, including involvement, engagement, and integration, provide common language and a body of knowledge to inform understanding of the challenges currently facing higher education. This paper examines how the theories and terms have evolved, explores how the terms are currently…
Directory of Open Access Journals (Sweden)
Wei Li
2017-01-01
Full Text Available We find that the solution of the polar angular differential equation can be written as the universal associated Legendre polynomials. Its generating function is applied to obtain an analytical result for a class of interesting integrals involving complicated argument, that is, ∫-11Pl′m′xt-1/1+t2-2xtPk′m′(x/(1+t2-2tx(l′+1/2dx, where t∈(0,1. The present method can in principle be generalizable to the integrals involving other special functions. As an illustration we also study a typical Bessel integral with a complicated argument ∫0∞Jn(αx2+z2/(x2+z2nx2m+1dx.
Nitecki, Elena
2015-01-01
The purpose of this study is to examine a preschool program with a high level of quality family involvement. Since family involvement during the early years has been linked to achievement and success in school, it is important to examine how such partnerships can be fostered in a meaningful way. The study employs an inductive qualitative approach,…
Gómez Rodríguez, Rafael Ángel
2014-01-01
To say that someone possesses integrity is to claim that that person is almost predictable about responses to specific situations, that he or she can prudentially judge and to act correctly. There is a closed interrelationship between integrity and autonomy, and the autonomy rests on the deeper moral claim of all humans to integrity of the person. Integrity has two senses of significance for medical ethic: one sense refers to the integrity of the person in the bodily, psychosocial and intellectual elements; and in the second sense, the integrity is the virtue. Another facet of integrity of the person is la integrity of values we cherish and espouse. The physician must be a person of integrity if the integrity of the patient is to be safeguarded. The autonomy has reduced the violations in the past, but the character and virtues of the physician are the ultimate safeguard of autonomy of patient. A field very important in medicine is the scientific research. It is the character of the investigator that determines the moral quality of research. The problem arises when legitimate self-interests are replaced by selfish, particularly when human subjects are involved. The final safeguard of moral quality of research is the character and conscience of the investigator. Teaching must be relevant in the scientific field, but the most effective way to teach virtue ethics is through the example of the a respected scientist.
Involvement of right STS in audio-visual integration for affective speech demonstrated using MEG.
Hagan, Cindy C; Woods, Will; Johnson, Sam; Green, Gary G R; Young, Andrew W
2013-01-01
Speech and emotion perception are dynamic processes in which it may be optimal to integrate synchronous signals emitted from different sources. Studies of audio-visual (AV) perception of neutrally expressed speech demonstrate supra-additive (i.e., where AV>[unimodal auditory+unimodal visual]) responses in left STS to crossmodal speech stimuli. However, emotions are often conveyed simultaneously with speech; through the voice in the form of speech prosody and through the face in the form of facial expression. Previous studies of AV nonverbal emotion integration showed a role for right (rather than left) STS. The current study therefore examined whether the integration of facial and prosodic signals of emotional speech is associated with supra-additive responses in left (cf. results for speech integration) or right (due to emotional content) STS. As emotional displays are sometimes difficult to interpret, we also examined whether supra-additive responses were affected by emotional incongruence (i.e., ambiguity). Using magnetoencephalography, we continuously recorded eighteen participants as they viewed and heard AV congruent emotional and AV incongruent emotional speech stimuli. Significant supra-additive responses were observed in right STS within the first 250 ms for emotionally incongruent and emotionally congruent AV speech stimuli, which further underscores the role of right STS in processing crossmodal emotive signals.
Welch, Bernadette; Vo-Tran, Huan; Pittayachawan, Siddhi; Reynolds, Sue
2012-01-01
The value of work integrated learning (WIL) is well-established in the education of information management (IM) professionals. Adding value to WIL through cross-cultural or cross-disciplinary experiences is considered in this article. Using online communication, simulation activities, and onsite work, students from RMIT Melbourne and RMIT Ho Chi…
ADDENDUM: Coupling coefficients of SO(n) and integrals involving Jacobi and Gegenbauer polynomials
Alisauskas, Sigitas
2004-01-01
A new and short proof of expression (3.2e) of Alisauskas (2002 J. Phys. A: Math. Gen. 35 7323) with obvious triangle conditions for integrals of the Jacobi polynomials is proposed, without any allusion to the special isofactors of Sp(4). Expressions (3.6c) and (3.12) are corrected.
Directory of Open Access Journals (Sweden)
Jiqiang Jiang
2012-01-01
Full Text Available We consider the existence of positive solutions for a class of nonlinear integral boundary value problems for fractional differential equations. By using some fixed point theorems, the existence and multiplicity results of positive solutions are obtained. The results obtained in this paper improve and generalize some well-known results.
Convexity of the integral operator involving normalized Mittag-Leffler function
Ćaǧlar, Murat; Yılmaz, Saip Emre; Deniz, Erhan
2017-04-01
The main object of this paper is to give sufficient condition for a certain family of integral operator which are defined by means of the normalized form of the Mittag-Leffler function to be convex of given order in the open unit disk.
Certain new integral formulas involving the generalized $k$-Bessel function
Directory of Open Access Journals (Sweden)
Kottakkaran S. Nisar
2017-08-01
Full Text Available In this present paper, we investigate generalized integration formulas containing the generalized $k$-Bessel function $W_{v,c}^{k}(z$ based on the well known Oberhettinger formula [12] and obtain the results in term of Wright-type function. Also, we establish certain special cases of our main result.
Kishore Prajapat, Jugal
2008-01-01
2000 Math. Subject Classification: 30C45 A known family of fractional integral operators is used here to define some new subclasses of analytic functions in the open unit disk U. For each of these new function classes, several inclusion relationships are established.
PERFORMANCE EVALUATION OF DISCRETE EVENT SYSTEMS INVOLVING HENSTOCK-KURZWEIL INTEGRAL
Institute of Scientific and Technical Information of China (English)
Calin CIUFUDEAN; Bianca SATCO
2009-01-01
This paper presents a study on the performance of flexible manufacturing systems (FMSs), by using discrete event system (DES) models, considering resource losses modelled by a parameter entitled coverage factor. We conclude that the resources cell loss distribution between the tasks of a FSM is a real function that cannot be integrated, in order to calculate its primitive, in the classical sense of Riemann or Lebesgue, but only in the sense of Henstock-Kurzweil integral. Our result allows one to study more general processes where highly oscillatory functions occur. The method used to deduce the function describing the resources cell loss distribution is compared with a classical method related in the literature, respectively rational interpolants. An example has been constructed to emphasize what we believe to be, new approaches.
Langhout, Regina Day; Rappaport, Julian; Simmons, Doretha
2002-01-01
Culturally relevant, ongoing project-based learning was facilitated in a predominantly African American urban elementary school via a community garden project. The project involved teachers, students, university members, and community members. This article evaluates the project through two classroom-community collaboration models, noting common…
Integrating social science knowledge into natural resource management public involvement practice
DEFF Research Database (Denmark)
Stummann, Cathy Brown
for public involvement practice the study suggests the development of an eclectic mix of social science knowledge for public NRM professionals to work with interpretively; and linking public NRM professionals’ practice-derived informal theories with the social science knowledge being introduced. While NRM...
Banerjee, Srijib; Furtmüller, Paul G; Obinger, Christian
2011-02-01
Lactoperoxidase (LPO), a member of the peroxidase-cyclooxygenase superfamily, is found in multiple human exocrine secretions and acts as a first line of defense against invading microorganisms by production of antimicrobial oxidants. Because of its ability to efficiently catalyze one- and two-electron oxidation reactions of inorganic and organic compounds, the heme peroxidase is widely used in food biotechnology, cosmetic industry, and diagnostic kits. In order to probe its structural integrity, conformational, and thermal stability, we have undertaken a comprehensive investigation by using complementary biophysical techniques including UV-Vis, circular dichroism and fluorescence spectroscopy as well as differential scanning calorimetry (DSC). The oxidoreductase exhibits a high chemical and thermal stability under oxidizing conditions but is significantly destabilized by addition of DTT. Due to its unique ester bonds between the prosthetic group and the protein as well as six intra-chain disulfides, unfolding of the central compact (-helical core occurs concomitantly with denaturation of the heme cavity. The corresponding enthalpic and entropic contributions to the free enthalpy of unfolding are presented. Together with spectroscopic data they will be discussed with respect to the known structure of bovine LPO and homologous myeloperoxidase as well as to its practical application.
Real-time electron dynamics simulation of two-electron transfer reactions induced by nuclear motion
Suzuki, Yasumitsu; Yamashita, Koichi
2012-04-01
Real-time electron dynamics of two-electron transfer reactions induced by nuclear motion is calculated by three methods: the numerically exact propagation method, the time-dependent Hartree (TDH) method and the Ehrenfest method. We find that, as long as the nuclei move as localized wave packets, the TDH and Ehrenfest methods can reproduce the exact electron dynamics of a simple charge transfer reaction model containing two electrons qualitatively well, even when nonadiabatic transitions between adiabatic states occur. In particular, both methods can reproduce the cases where a complete two-electron transfer reaction occurs and those where it does not occur.
Nandini, K E; Rastogi, Navin K
2011-01-01
The present work involves the adoption of an integrated approach for the purification of lactoperoxidase from milk whey by coupling aqueous two-phase extraction (ATPE) with ultrasound-assisted ultrafiltration. The effect of system parameters of ATPE such as type of phase system, polyethylene glycol (PEG) molecular mass, system pH, tie line length and phase volume ratio was evaluated so as to obtain differential partitioning of contaminant proteins and lactoperoxidase in top and bottom phases, respectively. PEG 6000-potassium phosphate system was found to be suitable for the maximum activity recovery of lactoperoxidase 150.70% leading to 2.31-fold purity. Further, concentration and purification of enzyme was attempted using ultrafiltration. The activity recovery and purification factor achieved after ultrafiltration were 149.85% and 3.53-fold, respectively. To optimise productivity and cost-effectiveness of integrated process, influence of ultrasound for the enhancement of permeate flux during ultrafiltration was also investigated. Intermittent use of ultrasound along with stirring (2 min acoustic and 2 min stirring) resulted in increased permeate flux from 0.94 to 2.18 l/m(2) h in comparison to the ultrafiltration without ultrasound. The use of ultrasound during ultrafiltration resulted in increase in flux, but there was no significant change in activity recovery and purification factor. The integrated approach involving ATPE and ultrafiltration may prove to be a feasible method for the downstream processing of lactoperoxidase from milk whey.
Energy Technology Data Exchange (ETDEWEB)
Errea, L.F.; Mendez, L.; Riera, A.
1983-06-01
In a previous paper we have pointed out that the common-translation-factor (CTF) method is the only one which, at present, and within the framework of the molecular model of atomic collisions, can be shown to be both convergent and computationally fast, even for many-electron systems. In this Communication we check that this second statement is correct, presenting, for the first time, a molecular calculation involving two-electron translation factors, for He/sup +/ + H collisions. A careful study of the sensitivity of the calculated cross sections to the choice of the CTF is performed, and conclusions on that sensitivity are drawn, for several types of processes.
Directory of Open Access Journals (Sweden)
Maarten S. De Waele
2014-09-01
Full Text Available Several major theories of crime causation have been applied to the study of violence towards persons and towards property (vandalism. Less frequently, these middle-range theoretical frameworks are applied to explain individual differences in political violence. Against a background of growing concern about right-wing political violence among adolescents, the present study examines the role of a number of independent variables derived from different theoretical frameworks in a sample of 2,879 Flemish adolescents. Using blockwise regression models, the independent effects of key independent variables from social control theory, procedural justice theory, general strain theory, social learning theory, and self-control theory are assessed. The results support an integrative approach towards the explanation of political violence. The implications of our findings for future studies on violent extremism are discussed.
A nonlinear wave equation with a nonlinear integral equation involving the boundary value
Directory of Open Access Journals (Sweden)
Thanh Long Nguyen
2004-09-01
Full Text Available We consider the initial-boundary value problem for the nonlinear wave equation $$displaylines{ u_{tt}-u_{xx}+f(u,u_{t}=0,quad xin Omega =(0,1,; 0
Integrating Virtual Reality and BIM for End-user Involvement in Building Design
DEFF Research Database (Denmark)
Petrova, Ekaterina Aleksandrova; Rasmussen, Mai; Jensen, Rasmus Lund
2017-01-01
. However, traditional practices place the responsibility of decision-making mostly in the architects’ hands. Virtual Reality technologies coupled with Building Information Modelling have the potential to improve the collaboration and data visualization in the building design. This paper presents...... the findings from a case study on the integration of Building Information Modelling and Virtual Reality for user-centred participatory interior furnishing of a new university building. Besides a significant reduction in the time for generation of alternative proposals, the end results show an increased...... attachment of the employees to their future workplace and a high level of acceptance towards the technology. Finally, the authors present suggestions for further work, which could improve future design processes utilizing the Virtual Reality technology....
Two-electron reduction of ethylene carbonate: a quantum chemistry re-examination of mechanisms
Leung, Kevin
2013-01-01
Passivating solid-electrolyte interphase (SEI) films arising from electrolyte decomposition on low-voltage lithium ion battery anode surfaces are critical for battery operations. We review the recent theoretical literature on electrolyte decomposition and emphasize the modeling work on two-electron reduction of ethylene carbonate (EC, a key battery organic solvent). One of the two-electron pathways, which releases CO gas, is re-examined using simple quantum chemistry calculations. Excess electrons are shown to preferentially attack EC in the order (broken EC^-) > (intact EC^-) > EC. This confirms the viability of two electron processes and emphasizes that they need to be considered when interpreting SEI experiments. An estimate of the crossover between one- and two-electron regimes under a homogeneous reaction zone approximation is proposed.
Vacuum polarization screening corrections to the ground state energy of two-electron ions
Artemiev, A N; Yerokhin, V A
1997-01-01
Vacuum polarization screening corrections to the ground state energy of two-electron ions are calculated in the range $Z=20-100$. The calculations are carried out for a finite nucleus charge distribution.
Delgado, María J.; Cerdá-Reverter, José M.; Soengas, José L.
2017-01-01
The regulation of food intake in fish is a complex process carried out through several different mechanisms in the central nervous system (CNS) with hypothalamus being the main regulatory center. As in mammals, a complex hypothalamic circuit including two populations of neurons: one co-expressing neuropeptide Y (NPY) and Agouti-related peptide (AgRP) and the second one population co-expressing pro-opiomelanocortin (POMC) and cocaine- and amphetamine-regulated transcript (CART) is involved in the integration of information relating to food intake control. The production and release of these peptides control food intake, and the production results from the integration of information of different nature such as levels of nutrients and hormones as well as circadian signals. The present review summarizes the knowledge and recent findings about the presence and functioning of these mechanisms in fish and their differences vs. the known mammalian model. PMID:28694769
Anti-Candida activity of geraniol involves disruption of cell membrane integrity and function.
Sharma, Y; Khan, L A; Manzoor, N
2016-09-01
Candidiasis is a major problem in immunocompromised patients. Candida, an opportunistic fungal pathogen, is a major health concern today as conventional drugs are highly toxic with undesirable side effects. Their fungistatic nature is responsible for drug resistance in continuously evolving strains. Geraniol, an acyclic monoterpene alcohol, is a component of several plant essential oils. In the present study, an attempt has been made to understand the antifungal activity of geraniol at the cell membrane level in three Candida species. With an MIC of 30-130μg/mL, this natural compound was fungicidal at concentrations 2×MIC. There was complete suppression of fungal growth at MIC values (growth curves) and encouragingly geraniol is non-toxic even at the concentrations approaching 5×MIC (hemolysis assay). Exposed cells showed altered morphology, wherein the cells appeared either broken or shrivelled up (SEM studies). Significant reduction was seen in ergosterol levels at sub-MIC and glucose-induced H(+) efflux at concentrations>MIC values. Our results suggest that geraniol disrupts cell membrane integrity by interfering with ergosterol biosynthesis and inhibiting the very crucial PM-ATPase. It may hence be used in the management and treatment of both superficial and invasive candidiasis but further studies are required to elaborate its mode of action.
Directory of Open Access Journals (Sweden)
Akbar Nabiollahi
2011-01-01
Full Text Available Problem statement: This study attempts to investigate and clarify the relationship of Service Knowledge Management System (SKMS with our primary study regard to using enterprise architecture through ITIL V3. Approach: SKMS concepts are introduced by ITIL V3 as a set of tools and databases that are used to manage knowledge and information of IT services. Results: The SKMS stores, retrieves, updates and presents all information that is expected for management of whole lifecycle of IT Services. Primary goal of our research is to provide a comprehensive integrated framework to determine and address IT Service Architecture requirements and related issues in ITIL V3 through using Enterprise Architecture. Conclusion/Recommendations: Through the main process of our study we realized that ITIL Knowledge Management process and its model for SKMS might be good candidates for storing and retrieving architectures of IT services. In other word, SKMS can be used as a set of tools and databases for management of architecture components of our target framework. For next step, the concern is how to develop proposed SKMS.
Mendoza-Suárez, A.; Pérez-Aguilar, H.
2016-09-01
We present several numerical integral methods for the study of a photonic crystal waveguide, formed by two parallel conducting plates and an array of circular inclusions involving a conducting material and a metamaterial. Band structures and reflectance were calculated, for infinite and finite photonic crystal waveguides, respectively. The numerical results obtained show that the numerical methods applied provide good accuracy and efficiency. An interesting detail that resulted from this study was the appearance of a propagating mode in a band gap due to defects in the middle of the photonic crystal waveguide. This is equivalent to dope a semiconductor to introduce allowed energy states within a band gap. Our main interest in this work is to model photonic crystal waveguides that involve left-handed materials (LHMs). For the specific LHM considered, a surface plasmon mode on the vacuum-LHM interface was found.
ATF4 is involved in the regulation of simulated microgravity induced integrated stress response
Li, Yingxian; Li, Qi; Wang, Xiaogang; Sun, Qiao; Wan, Yumin; Li, Yinghui; Bai, Yanqiang
Objective: Many important metabolic and signaling pathways have been identified as being affected by microgravity, thereby altering cellular functions such as proliferation, differentiation, maturation and cell survival. It has been demonstrated that microgravity could induce all kinds of stress response such as endoplasmic reticulum stress and oxidative stress et al. ATF4 belongs to the ATF/CREB family of basic region leucine zipper transcription factors. ATF4 is induced by stress signals including anoxia/hypoxia, ER stress, amino acid deprivation and oxidative stress. ATF4 regulates the expression of genes involved in oxidative stress, amino acid synthesis, differentiation, metastasis and angiogenesis. The aim of this study was to examine the changes of ATF4 under microgravity, and to investigate the role of ATF4 in microgravity induced stress. MethodsMEF cells were cultured in clinostat to simulate microgravity. Reverse transcription polymerase chain reaction (RT-PCR) and western blotting were used to examine mRNA and protein levels of ATF4 expression under simulated microgravity in MEF cells. ROS levels were measured with the use of the fluorescent signal H2DCF-DA. GFP-XBP1 stably transfected cell lines was used to detect the extent of ER stress under microgravity by the intensity of GFP. Dual luciferase reporter assay was used to detect the activity of ATF4. Co-immunoprecipitation was performed to analyze protein interaction. Results: ATF4 protein levels in MEF cells increased under simulated microgravity. However, ATF4 mRNA levels were consistent. XBP1 splicing can be induced due to ER stress caused by simulated microgravity. At the same time, ROS levels were also increased. Increased ATF4 could promote the expression of CHOP, which is responsible for cell apoptosis. ATF4 also play an important role in cellular anti-oxidant stress. In ATF4 -/-MEF cells, the ROS levels after H2O2 treatment were obviously higher than that of wild type cells. HDAC4 was
Involvement of ZFPIP/Zfp462 in chromatin integrity and survival of P19 pluripotent cells
Energy Technology Data Exchange (ETDEWEB)
Masse, Julie; Laurent, Audrey; Nicol, Barbara; Guerrier, Daniel; Pellerin, Isabelle; Deschamps, Stephane [UMR CNRS 6061, Institut of Genetique et Developpement de Rennes (IGDR), Faculte de Medecine, Universite de Rennes 1, 35043 Rennes cedex (France)
2010-04-15
Toti- or pluripotent cells proliferation and/or differentiation have been shown to be strongly related to nuclear chromatin organization and structure over the last past years. We have recently identified ZFPIP/Zfp462 as a zinc finger nuclear factor necessary for correct cell division during early embryonic developmental steps of vertebrates. We thus questioned whether this factor was playing a general role during cell division or if it was somehow involved in embryonic cell fate or differentiation. To achieve this goal, we performed a knock-down experiment in the pluripotent P19 and differentiated 3T3 cell lines, both expressing endogenous ZFPIP/Zfp462. Using specific shRNA directed against ZFPIP/Zfp462 transcripts, we demonstrated that depletion of this protein induced cell death in P19 but had no effect in 3T3 cells. In addition, in the absence of the protein, the P19 cells exhibited a complete destructuration of pericentromeric domains associated with a redistribution of the HP1{alpha} proteins and an increase in DNA satellites transcribed RNAs level. These data suggested an instrumental role of ZFPIP/Zfp462 in maintaining the chromatin structure of pluripotent cells.
ATLAS proton-proton event containing two electrons and two muons
ATLAS Collaboration
2011-01-01
An event with two identified muons and two identified electrons from a proton- proton collision in ATLAS. This event is consistent with coming from two Z particles decaying: one Z decays to two muons, the other to two electrons. Such events are produced by Standard Model processes without Higgs particles. They are also a possible signature for Higgs particle production, but many events must be analysed together in order to tell if there is a Higgs signal. The two muons are picked out as red tracks penetrating right through the detector. The two electrons are picked out as green tracks in the central, inner detector, matching narrow green clusters of energy in the barrel part of the calorimeters. The inset at the bottom right shows a map of the energy seen in the detector: the two big yellow spikes correspond to the two electrons.
Study of two-electron jumps in relaxation of Coulomb glasses
Energy Technology Data Exchange (ETDEWEB)
Bergli, J. [Department of Physics, University of Oslo, Blindern (Norway); Somoza, A.M.; Ortuno, M. [Departamento de Fisica - CIOyN, Universidad de Murcia (Spain)
2009-12-15
A long-standing debate in the theory of hopping insulators concerns the role of multi-electron transitions in the dynamics of the system. The natural assumption is that as temperature is lowered, two-electron transitions will play an increasingly important role since they provide a way of tunneling through additional energy barriers which would be energetically unfavorable as successive one-electron transitions. This was disputed in[1], but later it was seen in[2]. The reason for this discrepancy is not clear and deserves further attention. One point where the two approaches diverged was in the selection and weighting of the two-electron transitions relative to one-electron transitions. We present calculations of the transition rates to second order in the tunneling matrix element, which will be used in improved numerical studies. We compare results for only one-electron jumps with results including also two-electron jumps. (Abstract Copyright [2009], Wiley Periodicals, Inc.)
Role of Interactions in Electronic Structure of a Two-Electron Quantum Dot Molecule
Institute of Scientific and Technical Information of China (English)
DONG Qing-Rui; XU Ying-Qiang; ZHANG Shi-Yong; NIU Zhi-Chuan
2004-01-01
@@ We have studied a two-electron quantum dot molecule in a magnetic field. The electron interaction is treated accurately by the direct diagonalization of the Hamiltonian matrix. We calculate two lowest energy levels of the two-electron quantum dot molecule in a magnetic field. Our results show that the electron interactions are significant, as they can change the total spin of the two-electron ground state of the system by adjusting the magnetic field between S = 0 and S = 1. The energy difference △E between the lowest S = 0 and S = 1 states is shown as a function of the axial magnetic field. We found that the energy difference between the lowest S = 0 and S = 1 states in the strong-B S = 0 state varies linearly. Our results provide a possible realization for a qubit to be fabricated by current growth techniques.
Yu, Jiangliu; Li, Tao; Dai, Shang; Weng, Yulan; Li, Jiulong; Li, Qinghao; Xu, Hong; Hua, Yuejin; Tian, Bing
2017-01-01
The translocation and assembly module (TAM) in bacteria consists of TamA and TamB that form a complex to control the transport and secretion of outer membrane proteins. Herein, we demonstrated that the DR_1462-DR_1461-DR_1460 gene loci on chromosome 1 of Deinococcus radiodurans, which lacks tamA homologs, is a tamB homolog (DR_146T) with two tamB motifs and a DUF490 motif. Mutation of DR_146T resulted in cell envelope peeling and a decrease in resistance to shear stress and osmotic pressure, as well as an increase in oxidative stress resistance, consistent with the phenotype of a surface layer (S-layer) protein SlpA (DR_2577) mutant, demonstrating the involvement of DR_146T in maintenance of cell envelope integrity. The 123 kDa SlpA was absent and only its fragments were present in the cell envelope of DR_146T mutant, suggesting that DR_146T might be involved in maintenance of the S-layer. A mutant lacking the DUF490 motif displayed only a slight alteration in phenotype compared with the wild type, suggesting DUF490 is less important than tamB motif for the function of DR_146T. These findings enhance our understanding of the properties of the multilayered envelope in extremophilic D. radiodurans, as well as the diversity and functions of TAMs in bacteria. PMID:28383523
Directory of Open Access Journals (Sweden)
Laurel J. Trainor
2009-04-01
Full Text Available In a series of studies we have shown that movement (or vestibular stimulation that is synchronized to every second or every third beat of a metrically ambiguous rhythm pattern biases people to perceive the meter as a march or as a waltz, respectively. Riggle (this volume claims that we postulate an "innate", "specialized brain unit" for beat perception that is "directly" influenced by vestibular input. In fact, to the contrary, we argue that experience likely plays a large role in the development of rhythmic auditory-movement interactions, and that rhythmic processing in the brain is widely distributed and includes subcortical and cortical areas involved in sound processing and movement. Further, we argue that vestibular and auditory information are integrated at various subcortical and cortical levels along with input from other sensory modalities, and it is not clear which levels are most important for rhythm processing or, indeed, what a "direct" influence of vestibular input would mean. Finally, we argue that vestibular input to sound location mechanisms may be involved, but likely cannot explain the influence of vestibular input on the perception of auditory rhythm. This remains an empirical question for future research.
Directory of Open Access Journals (Sweden)
Nirmal V. Gnanapragasam, Bale V. Reddy, Marc A. Rosen
2011-01-01
Full Text Available The sustainability of a large-scale hydrogen production system is assessed qualitatively. The system uses solid fuels and aims to increase the sustainability of the energy system in Canada through the use of alternative energy forms. The system involves significant technology integration, with various energy conversion processes (e.g., gasification, chemical looping combustion, anaerobic digestion, combustion power cycles-electrolysis and solar-thermal convertors interconnected to increase the utilization of solid fuels as much as feasible in a sustainable manner within cost, environmental and other constraints. The qualitative analysis involves ten different indicators for each of the three dimensions of sustainability: ecology, sociology and technology, applied to each process in the system and assessed based on a ten-point quality scale. The results indicate that biomasses have better sustainability than coals while newer secondary processes are essential for primary conversion to be sustainable, especially when using coals. Also, new developments in CO2 use (for algae-to-oil and commercial applications and storage will in time help improve sustainability.
Silva, Franck; Reiter, Maud; Mills-Webb, Rebecca; Sawicki, Marcin; Klär, Daniel; Bensel, Nicolas; Wagner, Alain; Gouverneur, Véronique
2006-10-27
A novel palladium(II)-catalyzed oxy-carbopalladation process was developed allowing for the orchestrated union of hydroxy ynones with ethyl acrylate, two electron-deficient reactants. With beta-hydroxy ynones, this cascade Wacker-Heck process gave access to highly functionalized tri- or tetrasubstituted dihydropyranones featuring an unusual dienic system. For diastereomerically pure and for enantioenriched beta-hydroxyynones, these reactions proceed without affecting the stereochemical integrity of the existing stereocenters. In addition, tetrasubstituted furanones can be prepared when alpha-hydroxyynones and ethyl acrylate are used as starting materials. The dihydropyranones and furanones obtained upon cyclization are novel compounds, but structurally related carbohydrate derivatives featuring a similar dienic system have been used as starting materials for the construction of polyannulated products, suggesting that these cascade Pd(II)-mediated oxidative heterocyclizations are of value for various synthetic applications.
Quantum ballistic transport by interacting two-electron states in quasi-one-dimensional channels
Energy Technology Data Exchange (ETDEWEB)
Huang, Danhong [Air Force Research Laboratory, Space Vehicles Directorate, Kirtland Air Force Base, New Mexico 87117 (United States); Center for High Technology Materials, University of New Mexico, 1313 Goddard St SE, Albuquerque, New Mexico 87106 (United States); Gumbs, Godfrey [Center for High Technology Materials, University of New Mexico, 1313 Goddard St SE, Albuquerque, New Mexico 87106 (United States); Abranyos, Yonatan [Department of Physics and Astronomy, Hunter College of the City University of New York, 695 Park Avenue, New York, New York 10065 (United States); Pepper, Michael; Kumar, Sanjeev [Department of Electronic and Electrical Engineering, University College London, London, WC1E 7JE (United Kingdom); London Centre for Nanotechnology, 17-19 Gordon Street, London, WC1H 0AH (United Kingdom)
2015-11-15
For quantum ballistic transport of electrons through a short conduction channel, the role of Coulomb interaction may significantly modify the energy levels of two-electron states at low temperatures as the channel becomes wide. In this regime, the Coulomb effect on the two-electron states is calculated and found to lead to four split energy levels, including two anticrossing-level and two crossing-level states. Moreover, due to the interplay of anticrossing and crossing effects, our calculations reveal that the ground two-electron state will switch from one anticrossing state (strong confinement) to a crossing state (intermediate confinement) as the channel width gradually increases and then back to the original anticrossing state (weak confinement) as the channel width becomes larger than a threshold value. This switching behavior leaves a footprint in the ballistic conductance as well as in the diffusion thermoelectric power of electrons. Such a switching is related to the triple spin degeneracy as well as to the Coulomb repulsion in the central region of the channel, which separates two electrons away and pushes them to different channel edges. The conductance reoccurrence region expands from the weak to the intermediate confinement regime with increasing electron density.
Relaxation and Dephasing in a Two-Electron 13C Nanotube Double Quantum Dot
DEFF Research Database (Denmark)
Churchill, H O H; Kuemmeth, Ferdinand; Harlow, J W;
2009-01-01
We use charge sensing of Pauli blockade (including spin and isospin) in a two-electron 13C nanotube double quantum dot to measure relaxation and dephasing times. The relaxation time T1 first decreases with a parallel magnetic field and then goes through a minimum in a field of 1.4 T. We attribute...
Observation and spectroscopy of a two-electron Wigner molecule in an ultraclean carbon nanotube
DEFF Research Database (Denmark)
Pecker, S.; Kuemmeth, Ferdinand; Secchi, A.;
2013-01-01
Two electrons on a string form a simple model system where Coulomb interactions are expected to play an interesting role. In the presence of strong interactions, these electrons are predicted to form a Wigner molecule, separating to the ends of the string. This spatial structure is believed...
Calculation of differential cross section for dielectronic recombination with two-electron uranium
Lyashchenko, Konstantin N
2016-01-01
Calculation of the differential cross section for the dielectronic recombination with two-electron uranium within the framework of QED is presented. The polarization of the emitted photon is investigated. The contributions of the Breit interaction and the interference of the photon multipoles are studied.
Dimensionality effect on two-electron energy spectrum: A fractional-dimension-based formulation
Energy Technology Data Exchange (ETDEWEB)
Correa, R.; Gutiérrez, W.; Mikhailov, I. [Escuela de Física, Universidad Industrial de Santander, A.A. 678, Bucaramanga (Colombia); Fulla, M.R. [Escuela de Física, Universidad Nacional de Colombia, A.A. 3840, Medellín (Colombia); Marín, J.H., E-mail: jhmarin@unal.edu.co [Escuela de Física, Universidad Nacional de Colombia, A.A. 3840, Medellín (Colombia)
2015-07-17
We analyze the spectrum of two-electron quantum dot with anisotropic parabolic confinement by using the fractional-dimension formulation which allows us to reduce the two-particle problem to two equations for independent particles in an effective space with variable dimension, ranging between two and three for ellipsoidal-shaped quantum dots and between one and two for elliptical-shaped quantum disks. The dependencies of energy levels on the heterostructure sizes for quantum dots, disks and wires are presented. - Highlights: • We report the two-electron eigenenergies in a quantum dot with anisotropic parabolic confinement. • Our model is versatile enough to consider changes in the dimension space from 3 to 2 and 2 to 1. • The two-electron structure is calculated in integer and fractional dimensional spaces. • The two-electron energy structure is sensitive to the quantum dot size and morphology changes. • The electron–electron Coulomb interaction is strongly dependent on the space dimensionality.
Li, Li; Ren, Li; Liu, Wenming; Wang, Jian-Chun; Wang, Yaolei; Tu, Qin; Xu, Juan; Liu, Rui; Zhang, Yanrong; Yuan, Mao-Sen; Li, Tianbao; Wang, Jinyi
2012-08-07
Studies on the degeneration and regeneration of neurons as individual compartments of axons or somata can provide critical information for the clinical therapy of nervous system diseases. A controllable in vitro platform for multiple purposes is key to such studies. In the present study, we describe an integrated microfluidic device designed for achieving localized stimulation to neuronal axons or somata. We observed neuronal compartment degeneration after localized chemical stimulation and regeneration under the accessorial function of an interesting compound treatment or coculture with desired cells in controllable chambers. In a spatiotemporally controlled manner, this device was used to investigate hippocampal neuronal soma and axon degeneration after acrylamide stimulation, as well as subsequent regeneration after treatment with the monosialoganglioside GM1 or with cocultured glial cells (astrocytes or Schwann cells). To gain insight into the molecular mechanisms that mediate neuronal injury and regeneration, as well as to investigate whether acrylamide stimulation to neurons induces changes in Ca(2+) concentrations, the related neuronal genes and real-time Ca(2+) signal in neurons were also analyzed. The results showed that neuronal axons were more resistant to acrylamide injury than neuronal somata. Under localized stimulation, axons had self-destruct programs different from somata, and somatic injury caused the secondary response of axon collapse. This study provides a foundation for future in-depth analyses of spatiotemporally controlled and multifactor neuronal compartment regeneration after various injuries. The microfluidic device is also useful in evaluating potential therapeutic strategies to treat chemical injuries involving the central nervous system.
Eden, Lacey M.; Callister, Lynn Clark
2010-01-01
Survival rates for very preterm and critically ill infants are increasing, raising complex ethical issues for health-care providers and parents who face the challenge of making end-of-life decisions for newborns. The purpose of this integrative literature review was to evaluate parental involvement in end-of-life care and decision making for their infant in the newborn intensive care unit. Findings revealed that establishing good relationships and clear communication between health-care providers and parents builds trust and eases stress placed on parents making decisions about the care of their infant. Palliative care programs provide support for parents and facilitate their decision making. Parents can be educated about how to communicate with health-care providers. Educating nurses on how to provide end-of-life care may also help improve support for parents during this difficult time. Additional research is recommended to examine parents' needs during and after end-of-life care decisions for their newborn. PMID:21197127
Directory of Open Access Journals (Sweden)
Corinne Grenier
2011-02-01
Full Text Available Research question: We are looking at the process of structuring an integrated care system as an innovative process that swings back and forth between the diversity of the actors involved, local aspirations and national and regional regulations. We believe that innovation is enriched by the variety of the actors involved, but may also be blocked or disrupted by that diversity. Our research aims to add to other research, which, when questioning these integrated systems, analyses how the actors involved deal with diversity without really questioning it. Case study: The empirical basis of the paper is provided by case study analysis. The studied integrated care system is a French healthcare network that brings together healthcare professionals and various organisations in order to improve the way in which interventions are coordinated and formalised, in order to promote better detection and diagnosis procedures and the implementation of a care protocol. We consider this case as instrumental in developing theoretical proposals for structuring an integrated care system in light of the diversity of the actors involved. Results and discussion: We are proposing a model for structuring an integrated care system in light of the enacted diversity of the actors involved. This model is based on three factors: the diversity enacted by the leaders, three stances for considering the contribution made by diversity in the structuring process and the specific leading role played by those in charge of the structuring process. Through this process, they determined how the actors involved in the project were differentiated, and on what basis those actors were involved. By mobilizing enacted diversity, the leaders are seeking to channel the emergence of a network in light of their own representation of that network. This model adds to published research on the structuring of integrated care systems.
Directory of Open Access Journals (Sweden)
Corinne Grenier
2011-02-01
Full Text Available Research question: We are looking at the process of structuring an integrated care system as an innovative process that swings back and forth between the diversity of the actors involved, local aspirations and national and regional regulations. We believe that innovation is enriched by the variety of the actors involved, but may also be blocked or disrupted by that diversity. Our research aims to add to other research, which, when questioning these integrated systems, analyses how the actors involved deal with diversity without really questioning it.Case study: The empirical basis of the paper is provided by case study analysis. The studied integrated care system is a French healthcare network that brings together healthcare professionals and various organisations in order to improve the way in which interventions are coordinated and formalised, in order to promote better detection and diagnosis procedures and the implementation of a care protocol. We consider this case as instrumental in developing theoretical proposals for structuring an integrated care system in light of the diversity of the actors involved.Results and discussion: We are proposing a model for structuring an integrated care system in light of the enacted diversity of the actors involved. This model is based on three factors: the diversity enacted by the leaders, three stances for considering the contribution made by diversity in the structuring process and the specific leading role played by those in charge of the structuring process. Through this process, they determined how the actors involved in the project were differentiated, and on what basis those actors were involved. By mobilizing enacted diversity, the leaders are seeking to channel the emergence of a network in light of their own representation of that network. This model adds to published research on the structuring of integrated care systems.
Highly accurate wavefunctions for two-electron systems using two parameteres
Chauhan, Rabeet Singh
2015-01-01
It is shown for two electron atoms that ground-state wavefunctions of the form $\\Psi(\\vec{r_{1}}, \\vec{r_{2}})=\\phi(\\vec{r_{1}})\\phi(\\vec{r_{2}})(\\cosh ar_{1}+\\cosh ar_{2})(1+0.5 r_{12}e^{-b r_{12}})$ where $\\vec{r_{1}}$ and $\\vec{r_{2}}$ are the coordinates of two electrons and $r_{12}=|\\vec{r_{1}}-\\vec{r_{2}}|$, can be made highly accurate by optimizing $a$, $b$ and $\\phi$. This is done by solving a variationally derived equation for $\\phi$ for a given $a$ and $b$ and finding $a$ and $b$ so that the expectation value of the Hamiltonian is minimum. For the set $\\{a, b, \\phi\\}$ the values for various quantities obtained from the above wavefunction are compared with those given by $204$-parameter wavefunction of Koga et al. and are found to be matching quite accurately(within ppm) with them.
Energy Technology Data Exchange (ETDEWEB)
King, Paul W [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Lubner, Carolyn E [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Mulder, David W [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Zhang, Peng [Duke University; Yuly, Jonathon [Duke University; Peters, John W. [Washington State University; Beratan, David N. [Duke University
2017-09-06
How can proteins drive two electrons from a redox active donor onto two acceptors at very different potentials and distances? And how can this transaction be conducted without dissipating very much energy or violating the laws of thermodynamics? Nature appears to have addressed these challenges by coupling thermodynamically uphill and downhill electron transfer reactions, using two-electron donor cofactors that have very different potentials for the removal of the first and second electron. Although electron bifurcation is carried out with near perfection from the standpoint of energy conservation and electron delivery yields, it is a biological energy transduction paradigm that has only come into focus recently. This Account provides an exegesis of the biophysical principles that underpin electron bifurcation.
Coulomb barrier and exchange interaction in dynamical two-electron systems
Gregoire, Maxwell; Lougovski, Pavel; Batelaan, Herman
2012-06-01
Recent electron sources can produce pulses containing multiple electrons that are confined both laterally and longitudinally. Given that the highest reported degeneracy for continuous sources of free electrons is about 10-4, it would be interesting to know the degeneracy for these pulsed sources. We previously studied one-dimensional two-electron degeneracy [1], and we now study three-dimensional two-electron degeneracy as a function of time. Our primary goal is to use this project as a necessary step to studying three-dimensional n-electron degeneracy. Our second goal is to develop a theory that predicts the outcome of Hasselbach's experiment demonstrating the Hanbury Brown-Twiss Effect [2] for free electrons.[4pt] [1] Lougovski P, and Batelaan H, Phys. Rev. A 84, 023417 (2011).[0pt] [2] Kiesel H, Renz A, and Hasselbach F, Nature. 418, 392-4 (2002).
A compact terahertz free-electron laser with two gratings driven by two electron-beams
Liu, Weihao; Lu, Yalin; Wang, Lin; Jia, Qika
2017-02-01
We proposed and investigated a novel terahertz free-electron laser, which is based on two gratings driven by two electron-beams. Two gratings are symmetrically arranged to form an open-cavity. Two electron-beams generate special Smith-Purcell radiations, respectively, from two gratings. When radiation interferes constructively, operation modes of the open-cavity are excited and then amplified by beam-wave interactions. By means of particle-in-cell simulations, we have shown that, with compact equipments and available electron-beams, this scheme can generate radiation with power and efficiency being higher than those of majority radiation sources in the vicinity region of 1 THz. It can promisingly be developed as a high-power, high-efficiency, and compact terahertz source for practice.
The structure of approximate two electron wavefunctions in intense laser driven ionization dynamics
Sato, Takeshi
2014-01-01
The structure of approximate two electron wavefunction is deeply investigated, both theoretically and numerically, in the strong-field driven ionization dynamics. Theoretical analyses clarify that for two electron singlet systems, the previously proposed time-dependent extended Hartree-Fock (TD-EHF) method [Phys. Rev. A 51, 3999 (1995)] is equivalent to the multiconfiguration time-dependent Hartree-Fock method with two occupied orbitals. The latter wavefunction is further transformed into the natural expansion form, enabling the direct propagation of the natural orbitals (NOs). These methods, as well as the conventional time-dependent Hartree-Fock (TDHF) method, are numerically assessed for the description of ionization dynamics of one-dimensional helium atom model. This numerical analysis (i) explains the reason behind the well-known failure of TDHF method to describe tunneling ionization, (ii) demonstrates the interpretive power of the TD-EHF wavefunction both in the original nonorthogonal and the NO-based ...
Computation of energy states of hydrogenic quantum dot with two-electrons
Yakar, Y.; Özmen, A.; ćakır, B.
2016-03-01
In this study we have investigated the electronic structure of the hydrogenic quantum dot with two electrons inside an impenetrable potential surface. The energy eigenvalues and wavefunctions of the ground and excited states of spherical quantum dot have been calculated by using the Quantum Genetic Algorithm (QGA) and Hartree-Fock Roothaan (HFR) method, and the energies are investigated as a function of dot radius. The results show that as dot radius increases, the energy of quantum dot decreases.
Quantum Size Effects on Two Electrons and Two Holes in Double-Layer Quantum Dots
Institute of Scientific and Technical Information of China (English)
XIE Wen-Fang; ZHU Wu
2002-01-01
We propose a procedure to solve exactly the Schrodinger equation for a system of two electrons and two holes in a double-layer quantum dot by using the method of few-body physics. The features of the low-lying spectra have been deduced based on symmetry. The binding energies of the ground state are obtained as a function of the electron-to-hole mass ratio σ for a few values of the quantum dot size.
Two-Electron Energy Spectrum in a Parabolic Quantum Dot Under a Magnetic Field
Institute of Scientific and Technical Information of China (English)
XIE Wen-Fang
2003-01-01
Two interacting electrons in a harmonic oscillator potential under the influence of a perpendicular homo-geneous magnetic field are considered. The energies of two-electron quantum dots with the electron-LO-phonon couplingas a function of magnetic field are calculated. Calculations are made by using the method of few-body physics withinthe effective-mass approximation. Our results show that the electron-LO-phonon coupling effect is very important insemiconductor quantum dots.
Stevenson, Gareth P; Lee, Chong-Yong; Kennedy, Gareth F; Parkin, Alison; Baker, Ruth E; Gillow, Kathryn; Armstrong, Fraser A; Gavaghan, David J; Bond, Alan M
2012-06-26
A detailed analysis of the cooperative two-electron transfer of surface-confined cytochrome c peroxidase (CcP) in contact with pH 6.0 phosphate buffer solution has been undertaken. This investigation is prompted by the prospect of achieving a richer understanding of this biologically important system via the employment of kinetically sensitive, but background devoid, higher harmonic components available in the large-amplitude Fourier transform ac voltammetric method. Data obtained from the conventional dc cyclic voltammetric method are also provided for comparison. Theoretical considerations based on both ac and dc approaches are presented for cases where reversible or quasi-reversible cooperative two-electron transfer involves variation in the separation of their reversible potentials, including potential inversion (as described previously for solution phase studies), and reversibility of the electrode processes. Comparison is also made with respect to the case of a simultaneous two-electron transfer process that is unlikely to occur in the physiological situation. Theoretical analysis confirms that the ac higher harmonic components provide greater sensitivity to the various mechanistic nuances that can arise in two-electron surface-confined processes. Experimentally, the ac perturbation with amplitude and frequency of 200 mV and 3.88 Hz, respectively, was employed to detect the electron transfer when CcP is confined to the surface of a graphite electrode. Simulations based on cooperative two-electron transfer with the employment of reversible potentials of 0.745 ± 0.010 V, heterogeneous electron transfer rate constants of between 3 and 10 s(-1) and charge transfer coefficients of 0.5 for both processes fitted experimental data for the fifth to eighth ac harmonics. Imperfections in theory-experiment comparison are consistent with kinetic and thermodynamic dispersion and other nonidealities not included in the theory used to model the voltammetry of surface
Guo, Yutao; Chen, Yundai; Lane, Deirdre A; Liu, Lihong; Wang, Yutang; Lip, Gregory Y H
2017-08-26
Mobile Health technology for the management of patients with atrial fibrillation is unknown. The simple mobile AF (mAF) App was designed to incorporate clinical decision-support tools (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age ≥75 years, Diabetes Mellitus, Prior Stroke or TIA, Vascular disease, Age 65-74 years, Sex category], HAS-BLED [Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile INR, Elderly, Drugs/alcohol concomitantly], SAMe-TT2R2 [Sex, Age App vs usual care) in a cluster randomized design pilot study. Patients' knowledge, quality of life, drug adherence, and anticoagulation satisfaction were evaluated at baseline, 1 month, and 3 months. Usability, feasibility, and acceptability of the mAF App were assessed at 1 month. A total of 113 patients were randomized to mAF App intervention (mean age, 67.4 years; 57.5% were male; mean follow-up, 69 days), and 96 patients were randomized to usual care (mean age, 70.9 years; 55.2% were male; mean follow-up, 95 days). More than 90% of patients reported that the mAF App was easy, user-friendly, helpful, and associated with significant improvements in knowledge compared with the usual care arm (P values for trend App versus usual care (all P App arm versus usual care, with anxiety and depression reduced (all P App, integrating clinical decision support,education, and patient-involvement strategies, significantly improved knowledge, drug adherence, quality of life, and anticoagulation satisfaction. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.
Frustrated double and single ionization in a two-electron triatomic molecule H$^+_3$
Chen, A; Price, H; Emmanouilidou, A
2016-01-01
Using a semi-classical model, we study the formation of highly excited neutral fragments during the fragmentation of $\\mathrm{H_3^+}$, a two-electron triatomic molecule, driven by an intense near-IR laser field. To do so, we first formulate a microcanonical distribution for arbitrary one-electron triatomic molecules. We then study frustrated double and single ionization in strongly-driven $\\mathrm{H_3^+}$ and compute the kinetic energy release of the nuclei for these two processes. Moreover, we investigate the dependence of frustrated ionization on the strength of the laser field as well as on the geometry of the initial molecular state.
Effect of Coulomb Interaction on Dynamical Localization in a Two-Electron Quantum-Dot Molecule
Institute of Scientific and Technical Information of China (English)
WANG Li-Min; DUAN Su-Qing; ZHAO Xian-Geng; LIU Cheng-Shi
2004-01-01
The combined interaction of Coulomb interaction and ac fields with two electrons in a quantum dot molecule is studied respectively with numerical simulation, perturbation theory and the approximation of driven two-level model. The dynamical localization occurs with the ac field whose ratio of the amplitude to the angular frequency is a root of n-order Bessel functions, where n is determined by the Coulomb interaction energy. Such results are explained with either the driven two-level approximation or the degenerated three-level model and verified by the numerical simulations.
t-SURFF: Fully Differential Two-Electron Photo-Emission Spectra
Scrinzi, Armin
2012-01-01
The time dependent surface flux (t-SURFF) method is extended to single and double ionization of two electron systems. Fully differential double emission spectra by strong pulses at extreme UV and infrared wave length are calculated using simulation volumes that only accommodate the effective range of the atomic binding potential and the quiver radius of free electrons in the external field. For a model system we find pronounced dependence of shake-up and non-sequential double ionization on phase and duration of the laser pulse. Extension to fully three-dimensional calculations is discussed.
Theory of Square-Wave Voltammetry of Two-Electron Reduction with the Adsorption of Intermediate
Directory of Open Access Journals (Sweden)
Milivoj Lovric
2012-01-01
Full Text Available Thermodynamically unstable intermediate of fast and reversible two-electron electrode reaction can be stabilized by the adsorption to the electrode surface. In square-wave voltammetry of this reaction mechanism, the split response may appear if the electrode surface is not completely covered by the adsorbed intermediate. The dependence of the difference between the net peak potentials of the prepeak and postpeak on the square-wave frequency is analyzed theoretically. This relationship can be used for the estimation of adsorption constant.
Dynamic Localization Condition of Two Electrons in a Strong dc-ac Biased Quantum Dot Molecule
Institute of Scientific and Technical Information of China (English)
WANG Li-Min; DUAN Su-Qing; ZHAO Xian-Geng; LIU Cheng-Shi
2004-01-01
@@ We present a perturbation investigation of dynamic localization condition of two electrons in a strong dc-ac biased quantum dot molecule. By reducing the system to an Hubbard-type effective two-site model and by applying Floquet theory, we find that the dynamical localization phenomenon occurs under certain values of the large strength of the dc and ac field. This demonstrates the possibility of using appropriate dc-ac fields to manipulate dynamical localized states in mesoscopic devices, which is an essential component of practical schemes for quantum information processing. Our conclusion is instructive to the field of quantum function devices.
Two-electron Oxidation of a Twisted Non Anti-aromatic 40π Expanded Isophlorin
Indian Academy of Sciences (India)
PRACHI GUPTA; SANTOSH P PANCHAL; VENKATARAMANARAO G ANAND
2016-11-01
Expanded isophlorins are typical examples for stable anti-aromatic systems. Paratropic ring current effects are observed in their NMR spectra mainly due to their planar conformation. Herein we report the synthesis of the first twisted 40π expanded isophlorin and also its two-electron oxidation to a 38π dication. It sustains the twisted conformation for the 4nπ and (4n+2)π electrons. Due to the non-planar conformation, they do not display ring current effects in their respective 1H NMR spectrum. NICS calculations reveal the non-(anti)aromatic features for the neutral 40π and the 38π dication species.
Relaxation and Dephasing in a Two-Electron 13C Nanotube Double Quantum Dot
DEFF Research Database (Denmark)
Churchill, H O H; Kuemmeth, Ferdinand; Harlow, J W
2009-01-01
We use charge sensing of Pauli blockade (including spin and isospin) in a two-electron 13C nanotube double quantum dot to measure relaxation and dephasing times. The relaxation time T1 first decreases with a parallel magnetic field and then goes through a minimum in a field of 1.4 T. We attribute...... both results to the spin-orbit-modified electronic spectrum of carbon nanotubes, which at high field enhances relaxation due to bending-mode phonons. The inhomogeneous dephasing time T2* is consistent with previous data on hyperfine coupling strength in 13C nanotubes....
Comparative characterization of two-electron wavefunctions using information-theory measures
Energy Technology Data Exchange (ETDEWEB)
Howard, I.A., E-mail: ihoward@vub.ac.b [Department of Chemistry (ALGC), Free University of Brussels (VUB), B-1050, Brussels, Belgium/Member of the QCMM-Alliance Ghent-Brussels (Belgium); Borgoo, A.; Geerlings, P. [Department of Chemistry (ALGC), Free University of Brussels (VUB), B-1050, Brussels, Belgium/Member of the QCMM-Alliance Ghent-Brussels (Belgium); Sen, K.D. [School of Chemistry, University of Hyderabad, Hyderabad 500046 (India)
2009-08-31
Information-theory measures, in particular the Shannon entropy, Fisher information and statistical complexity, are used to discuss the variations among several commonly encountered model two-electron correlated wavefunctions. The Hookean, Moshinsky, and three-parameter Chandrasekhar wavefunctions are considered in real and momentum space, with further comparisons to the Hookean-Hartree-Fock (HF) wavefunction of Ragot, the numerical HF limit, and the hydrogenic (pure Coulomb) limit. The purpose of the study is to quantitatively analyze the effect of different models for inclusion of electron-electron correlation on information-theoretical measures, including statistical complexity, which characterize the electron distribution in position and momentum space.
Indian Academy of Sciences (India)
M Akbari-Moghanjoughi; N Ahmadzadeh-Khosroshahi
2011-08-01
Oblique interaction of small- but ﬁnite-amplitude KdV-type electron-acoustic solitary excitations is examined in an unmagnetized two-electron-populated degenerate quantum electron–ion plasma in the framework of quantum hydrodynamics model using the extended Poincaré–Lighthill–Kuo (PLK) perturbation method. Critical plasma parameter is found to distinguish the types of solitons and their interaction phase-shifts. It is shown that, depending on the critical quantum diffraction parameter cr, both compressive and rarefactive solitary excitations may exist in this plasma and their collision phase-shifts can be either positive or negative for the whole range of collision angles 0 < θ < .
Dawson, Kara; Ritzhaupt, Albert; Liu, Feng; Rodriguez, Prisca; Frey, Christopher
2013-01-01
The purpose of this study was to examine the ways teachers enact technological, pedagogical and content practices in math and science lessons and to document the change with teachers involved in a year-long technology integration initiative. Six hundred seventy-two lessons were analyzed in this research using Technological, Pedagogical Content…
Giesbertz, K J H; Pernal, K; Gritsenko, O V; Baerends, E J
2009-03-21
Time-dependent density functional theory in its current adiabatic implementations exhibits three striking failures: (a) Totally wrong behavior of the excited state surface along a bond-breaking coordinate, (b) lack of doubly excited configurations, affecting again excited state surfaces, and (c) much too low charge transfer excitation energies. We address these problems with time-dependent density matrix functional theory (TDDMFT). For two-electron systems the exact exchange-correlation functional is known in DMFT, hence exact response equations can be formulated. This affords a study of the performance of TDDMFT in the TDDFT failure cases mentioned (which are all strikingly exhibited by prototype two-electron systems such as dissociating H(2) and HeH(+)). At the same time, adiabatic approximations, which will eventually be necessary, can be tested without being obscured by approximations in the functional. We find the following: (a) In the fully nonadiabatic (omega-dependent, exact) formulation of linear response TDDMFT, it can be shown that linear response (LR)-TDDMFT is able to provide exact excitation energies, in particular, the first order (linear response) formulation does not prohibit the correct representation of doubly excited states; (b) within previously formulated simple adiabatic approximations the bonding-to-antibonding excited state surface as well as charge transfer excitations are described without problems, but not the double excitations; (c) an adiabatic approximation is formulated in which also the double excitations are fully accounted for.
Simulation of molecular Auger spectra using a two-electron Dyson propagator
Energy Technology Data Exchange (ETDEWEB)
Hori, Y.; Nishida, M.; Lim, F.H.; Ida, T., E-mail: ida@se.kanazawa-u.ac.jp; Mizuno, M.
2016-02-15
Highlights: • Auger electron spectra (AES) simulation using a new two-electron Dyson propagator. • Double ionization potentials can be accurately and efficiently computed. • The proposal method is useful for belonging peaks in AES of molecule. - Abstract: In order to simulate Auger electron spectra (AES), we propose the use of the two-electron Dyson propagator with the shifted denominator approximation (SD2). The double ionization potentials (DIPs) of molecules calculated using the SD2 method have shown good agreement with experimental data. This method can be used to calculate each DIP separately, and reducing the matrix dimensionality into that of only a two-hole configurations. We carried out AES simulations of water (H{sub 2}O), ethylene (C{sub 2}H{sub 4}), and formaldehyde (H{sub 2}CO) molecules and compared with the observed spectra. Furthermore Auger line shapes of glycine and hydrated glycine molecules were simulated, it found out that the peaks of nitrogen K-LL Auger were broadened due to hydration. From these results, we conclude that the SD2 method is very useful for the calculation of DIPs to investigate the properties of a double ionized molecule.
Ion-acoustic solitons in negative ion plasma with two-electron temperature distributions
Energy Technology Data Exchange (ETDEWEB)
Mishra, M. K.; Tiwari, R. S.; Chawla, J. K. [Department of Physics, University of Rajasthan, Jaipur-302004 (India)
2012-06-15
Ion-acoustic solitons in a warm positive and negative ion species with different masses, concentrations, and charge states with two electron temperature distributions are studied. Using reductive perturbation method, Korteweg de-Vries (KdV) and modified-KdV (m-KdV) equations are derived for the system. The soliton solution of the KdV and m-KdV equations is discussed in detail. It is found that if the ions have finite temperatures, then there exist two types of modes, namely slow and fast ion-acoustic modes. It is also investigated that the parameter determining the nature of soliton (i.e., whether the system will support compressive or rarefactive solitons) is different for slow and fast modes. For the slow mode, the parameter is the relative temperature of the two ion species; whereas for the fast mode, it is the relative concentration of the two ion species. At a critical concentration of negative ions, both compressive and rarefactive solitons coexist. The amplitude and width of the solitons are discussed in detail at critical concentration for m-KdV solitons. The effect of the relative temperature of the two-electron and cold-electron concentration on the characteristics of the solitons are also discussed.
Two-electron electrochemical oxidation of quercetin and kaempferol changes only the flavonoid C-ring
DEFF Research Database (Denmark)
Jørgensen, Lars; Cornett, Claus; Justesen, Ulla
1998-01-01
Bulk electrolysis of the antioxidant flavonoids quercetin and kaempferol in acetonitrile both yield a single oxidation product in two-electron processes. The oxidation products are more polar than their parent compounds, with an increased molecular weight of 16g/mol, and were identified as 2......-(3,4-dihydroxybenzoyl)-2,4,6-trihydroxy-3 (2H)-benzofuranone and 2-(4-hydroxybenzoyl)-2,4,6-trihydroxy-3(2H)-benzofuranone for quercetin and kaempferol, respectively. Two-electron oxidation of the parent flavonoid is suggested to yield a 3,4-flavandione with unchanged substitution pattern in the A- and B-ring, which...... may rearrange to form the substituted 3(2H)-benzofuranone through the chalcan-trione ring-chain tautomer. The acidity of the 3-OH group is suggested to determine the fate of the flavonoid phenoxyl radical originally formed by one-electron oxidation, as no well-defined oxidation product of luteolin...
Quantum Interferometry and Correlated Two-Electron Wave-Packet Observation in Helium
Ott, Christian; Raith, Philipp; Meyer, Kristina; Laux, Martin; Zhang, Yizhu; Hagstotz, Steffen; Ding, Thomas; Heck, Robert; Pfeifer, Thomas
2012-01-01
The concerted motion of two or more bound electrons governs atomic and molecular non-equilibrium processes and chemical reactions. It is thus a long-standing scientific dream to measure the dynamics of two bound correlated electrons in the quantum regime. Quantum wave packets were previously observed for single-active electrons on their natural attosecond timescales. However, at least two active electrons and a nucleus are required to address the quantum three-body problem. This situation is realized in the helium atom, but direct time-resolved observation of two-electron wave-packet motion remained an unaccomplished challenge. Here, we measure a 1.2-femtosecond quantum beating among low-lying doubly-excited states in helium to evidence a correlated two-electron wave packet. Our experimental method combines attosecond transient-absorption spectroscopy at unprecedented high spectral resolution (20 meV near 60 eV) with an intensity-tuneable visible laser field to couple the quantum states from the perturbative ...
Quantum entanglement for two electrons in the excited states of helium-like systems
Lin, Yen-Chang
2013-01-01
The quantum entanglement for the two electrons in the excited states of the helium-like atom/ions is investigated using the two-electron wave functions constructed by the B-spline basis. As a measure of the spatial (electron-electron orbital) entanglement, the von Neumann entropy and linear entropy of the reduced density matrix are calculated for the 1s2s 1,3S excited states for systems with some selected Z values from Z=2 to Z=100. Results for the helium atom are compared with other available calculations. We have also investigated the entropies for these excited states when the nucleus charge is reduced from Z=2 to Z=1. At such a critical charge, all the singly-excited states of this system become unbound, and the linear entropies and the von Neumann entropies for the excited states are approaching 1/2 and 1, respectively, the limits for the entropies when one electron is bound to the nucleus, and the other being free.
2010-10-01
... REGULATIONS ON SAFETY INTEGRATION PLANS GOVERNING RAILROAD CONSOLIDATIONS, MERGERS, AND ACQUISITIONS OF... train control devices and systems; (6) Hazardous materials personnel, including information technology... communication standards; (3) Emergency response procedures; and (4) Information technology systems and...
DEFF Research Database (Denmark)
Emerek, Ruth
2004-01-01
Bidraget diskuterer de forskellige intergrationsopfattelse i Danmark - og hvad der kan forstås ved vellykket integration......Bidraget diskuterer de forskellige intergrationsopfattelse i Danmark - og hvad der kan forstås ved vellykket integration...
Multicenter molecular integrals for Slater orbitals of higher principal quantum numbers
Tai, H.
1989-01-01
As was shown earlier by Tai (1979), by using the Fourier-transform technique and properly coupling a pair of two-center exchange integrals, the multicenter molecular integrals can be cast into a simple expression upon which numerical procedures can be directly applied. In this paper, the procedure of Tai is extended to integrals involving orbitals with arbitrarily higher principal quantum number. The derivation is outlined, and the explicit expressions are presented for a three-center nuclear attraction integral and a four-center two-electron Coulomb repulsion integral of arbitrary higher states.
Wakunuma, Kutoma; Rainey, Stephen; Hansen, Christian
2017-01-01
Research on Brain Computer Interfaces (BCI) often aims to provide solutions for vulnerable populations, such as individuals with diseases, conditions or disabilities that keep them from using traditional interfaces. Such research thereby contributes to the public good. This contribution to the public good corresponds to a broader drive of research and funding policy that focuses on promoting beneficial societal impact. One way of achieving this is to engage with the public. In practical terms this can be done by integrating civil society organisations (CSOs) in research. The open question at the heart of this paper is whether and how such CSO integration can transform the research and contribute to the public good. To answer this question the paper describes five detailed qualitative case studies of research projects including CSOs. The paper finds that transformative impact of CSO integration is possible but by no means assured. It provides recommendations on how transformative impact can be promoted. PMID:28207882
Çakır, Bekir; Yakar, Yusuf; Özmen, Ayhan
2015-02-01
Linear and nonlinear absorption coefficients of two-electron spherical quantum dot (QD) with parabolic potential are investigated in this paper. Wave functions and energy eigenvalues of the 1s2, 1s1p, 1s1d and 1s1f electronic states have been computed by using an optimization approach, which is a combination of Quantum Genetic Algorithm (QGA) and Hartree-Fock Roothaan (HFR) method. It is found that the strength of S→P transition is stronger than P→D and D→F transitions. Also the peak positions and amplitudes of the absorption coefficients are sensitive to the electron spin. It should be noted that the peak positions and amplitudes of absorption coefficients are strongly dependent on the parabolic potential. Additionally, dot radius, impurity charge, incident optical intensity and relaxation time have a great influence on the linear and nonlinear absorption coefficients.
Electronic structure of two-electron quantum dot with parabolic potential
Yakar, Yusuf; Çakır, Bekir; Özmen, Ayhan
2015-01-01
In this study, we investigate the parabolic potential effects on the ground and excited energy states of two-electron quantum dot with impurity inside an infinite spherical confining potential well. The wave function and energy eigenvalues were calculated using a modified variational optimization procedure based mainly on quantum genetic algorithm and Hartree-Fock-Roothaan method. The results show that the parabolic potential and impurity charge have a strong effect on the energy states and ionization energies. It is worth pointing out that as impurity charge increases, the ionization energy rises, but the ionization dot radius decreases. On the other hand, as parabolic potential increases, the ionization energy decreases, but the ionization dot radius increases.
Energy Technology Data Exchange (ETDEWEB)
Çakır, Bekir, E-mail: bcakir@selcuk.edu.tr [Physics Department, Faculty of Science, Selcuk University, Campus 42075, Konya (Turkey); Yakar, Yusuf, E-mail: yuyakar@yahoo.com [Physics Department, Faculty of Arts and Science, Aksaray University, Campus 68100, Aksaray (Turkey); Özmen, Ayhan [Physics Department, Faculty of Science, Selcuk University, Campus 42075, Konya (Turkey)
2015-02-01
Linear and nonlinear absorption coefficients of two-electron spherical quantum dot (QD) with parabolic potential are investigated in this paper. Wave functions and energy eigenvalues of the 1s{sup 2}, 1s1p, 1s1d and 1s1f electronic states have been computed by using an optimization approach, which is a combination of Quantum Genetic Algorithm (QGA) and Hartree–Fock Roothaan (HFR) method. It is found that the strength of S→P transition is stronger than P→D and D→F transitions. Also the peak positions and amplitudes of the absorption coefficients are sensitive to the electron spin. It should be noted that the peak positions and amplitudes of absorption coefficients are strongly dependent on the parabolic potential. Additionally, dot radius, impurity charge, incident optical intensity and relaxation time have a great influence on the linear and nonlinear absorption coefficients.
Ground State of a Two-Electron Quantum Dot with a Gaussian Confining Potential
Institute of Scientific and Technical Information of China (English)
XIE Wen-Fang
2006-01-01
We investigate the ground-state properties of a two-dimensional two-electron quantum dot with a Gaussian confining potential under the influence of perpendicular homogeneous magnetic field. Calculations are carried out by using the method of numerical diagonalization of Hamiltonian matrix within the effective-mass approximation. A ground-state behaviour (singlet→triplet state transitions) as a function of the strength of a magnetic field has been found. It is found that the dot radius R of the Gaussian potential is important for the ground-state transition and the feature of ground-state for the Gaussian potential quantum dot (QD), and the parabolic potential QDs are similar when R is larger. The larger the quantum dot radius, the smaller the magnetic field for the singlet-triplet transition of the ground-state of two interacting electrons in the Gaussian quantum dot.
Exact equations of motion for natural orbitals of strongly driven two-electron systems
Rapp, J; Bauer, D
2014-01-01
Natural orbital theory is a computationally useful approach to the few and many-body quantum problem. While natural orbitals are known and applied since many years in electronic structure applications, their potential for time-dependent problems is being investigated only since recently. Correlated two-particle systems are of particular importance because the structure of the two-body reduced density matrix expanded in natural orbitals is known exactly in this case. However, in the time-dependent case the natural orbitals carry time-dependent phases that allow for certain time-dependent gauge transformations of the first kind. Different phase conventions will, in general, lead to different equations of motion for the natural orbitals. A particular phase choice allows us to derive the exact equations of motion for the natural orbitals of any (laser-) driven two-electron system explicitly, i.e., without any dependence on quantities that, in practice, require further approximations. For illustration, we solve th...
Energy Technology Data Exchange (ETDEWEB)
Lobayan, Rosana M., E-mail: rmlb@exa.unne.edu.ar [Departamento de Física, Facultad de Ciencias Exactas, Naturales y Agrimensura, Universidad Nacional del Nordeste, 3400, Corrientes (Argentina); Bochicchio, Roberto C., E-mail: rboc@df.uba.ar [Departamento de Física, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, and IFIBA, CONICET, Ciudad Universitaria, 1428, Buenos Aires (Argentina)
2014-05-07
Two-electron three-center bonding interactions in organic ions like methonium (CH{sub 5}{sup +}), ethonium (C{sub 2}H{sub 7}{sup +}), and protonated alkanes n−C{sub 4}H{sub 11}{sup +} isomers (butonium cations) are described and characterized within the theoretical framework of the topological analysis of the electron density decomposition into its effectively paired and unpaired contributions. These interactions manifest in some of this type of systems as a concentration of unpaired electron cloud around the bond paths, in contrast to the well known paradigmatic boron hydrids in which it is not only concentrated close to the atomic nucleus and the bond paths but out of them and over the region defined by the involved atoms as a whole. This result permits to propose an attempt of classification for these interactions based in such manifestations. In the first type, it is called as interactions through bonds and in the second type as interactions through space type.
Brics, M; Bauer, D
2016-01-01
Recently introduced time-dependent renormalized-natural-orbital theory (TDRNOT) is based on the equations of motion for the so-called natural orbitals, i.e., the eigenfunctions of the one-body reduced density matrix. Exact TDRNOT can be formulated for any time-dependent two-electron system in either spin configuration. In this paper, the method is tested against high-order harmonic generation (HHG) and Fano profiles in absorption spectra with the help of a numerically exactly solvable one-dimensional model He atom, starting from the spin-singlet ground state. Such benchmarks are challenging because Fano profiles originate from transitions involving autoionizing states, and HHG is a strong-field phenomenon well beyond linear response. TDRNOT with just one natural orbital per spin in the helium spin-singlet case is equivalent to time-dependent Hartree-Fock or time-dependent density functional theory (TDDFT) in exact exchange-only approximation. It is not unexpected that TDDFT fails in reproducing Fano profiles ...
Wang, Mei-jung
2014-01-01
The effective and confident integration of information communication technology (ICT) tools and programs can be frustrating. Hence, providing emotional support for teachers who are willing to adopt ICT in language instruction is an issue worthy of attention. In order to promote ICT-supported language instruction, this study aims to identify the…
Directory of Open Access Journals (Sweden)
Sergey K. Sekatskii
2015-01-01
Full Text Available Integral equalities involving integrals of the logarithm of the Riemann ς-function with exponential weight functions are introduced, and it is shown that an infinite number of them are equivalent to the Riemann hypothesis. Some of these equalities are tested numerically. The possible contribution of the Riemann function zeroes nonlying on the critical line is rigorously estimated and shown to be extremely small, in particular, smaller than nine milliards of decimals for the maximal possible weight function exp(−2πt. We also show how certain Fourier transforms of the logarithm of the Riemann zeta-function taken along the real (demiaxis are expressible via elementary functions plus logarithm of the gamma-function and definite integrals thereof, as well as certain sums over trivial and nontrivial Riemann function zeroes.
Sajid, Ayesha; Whiteman, Aaron; Bell, Richard L.; Greene, Marion S.; Engleman, Eric A; Chambers, R. Andrew
2016-01-01
Background and Objectives Fourfold increases in opioid prescribing and dispensations over 2 decades in the U.S. has paralleled increases in opioid addictions and overdoses, requiring new preventative, diagnostic, and treatment strategies. This study examines Prescription Drug Monitoring Program (PDMP) tracking as a novel measure of opioid addiction treatment outcomes in a university‐affiliated integrated mental health‐addiction treatment clinic. Methods Repeated measure parametrics examined P...
Sole, Isabel; Miras, Mariana; Castells, Nuria; Espino, Sandra; Minguela, Marta
2013-01-01
The case study reported here explores the processes involved in producing a written synthesis of three history texts and their possible relation to the characteristics of the texts produced and the degree of comprehension achieved following the task. The processes carried out by 10 final-year compulsory education students (15 and 16 years old) to…
Energy Technology Data Exchange (ETDEWEB)
Imbert, A.; Chaffanet, M.; Birnbaum, D.; Pebusque, M.J. [INSERM, Marseille (France)] [and others
1996-02-15
This article discusses the genetic mapping of the specific region on human chromosome 8, 8p12-p21, and its implications to human hereditary cancers and diseases. The localization of disease genes such as NEFL and FGFR1 are given, accomplished using contigs which span the region of deletion involved in these hereditary diseases. 59 refs., 4 figs., 3 tabs.
Albers, Sonja-V.; Elferink, Marieke G.L.; Charlebois, Robert L.; Sensen, Christoph W.; Driessen, Arnold J.M.; Konings, Wil N.
1999-01-01
The archaeon Sulfolobus solfataricus grows optimally at 80°C and pH 2.5 to 3.5 on carbon sources such as yeast extracts, tryptone, and various sugars. Cells rapidly accumulate glucose. This transport activity involves a membrane-bound glucose-binding protein that interacts with its substrate with
Argus, Kevin James
2017-01-01
This thesis explores the formative antecedents and stages leading to consumers’ enduring involvement (EI) and loyalty with brands and products. This aim was pursued by conducting a study of sport consumers, of varying duration and intensity of EI and loyalty. A further aim was to determine whether the motives of consumers’ transitions between these stages of EI provide insights that explain their transitions between stages of brand loyalty and/or product loyalty. Of pa...
Guo, Ya; Zhu, Xiao-Dong; Qu, Song; Li, Ling; Su, Fang; Li, Ye; Huang, Shi-Ting; Li, Dan-Rong
2012-01-01
Radioresistance remains one of the important factors in relapse and metastasis of nasopharyngeal carcinoma. Thus, it is imperative to identify genes involved in radioresistance and explore the underlying biological processes in the development of radioresistance. In this study, we used cDNA microarrays to select differential genes between radioresistant CNE-2R and parental CNE-2 cell lines. One hundred and eighty-three significantly differentially expressed genes (pgenes were upregulated and 45 genes were downregulated in CNE-2R. We further employed publicly available bioinformatics related software, such as GOEAST and STRING to examine the relationship among differentially expressed genes. The results show that these genes were involved in type I interferon-mediated signaling pathway biological processes; the nodes tended to have high connectivity with the EGFR pathway, IFN-related pathways, NF-κB. The node STAT1 has high connectivity with other nodes in the protein-protein interaction (PPI) networks. Finally, the reliability of microarray data was validated for selected genes by semi-quantitative RT-PCR and Western blotting. The results were consistent with the microarray data. Our study suggests that microarrays combined with gene ontology and protein interaction networks have great value in the identification of genes of radioresistance in nasopharyngeal carcinoma; genes involved in several biological processes and protein interaction networks may be relevant to NPC radioresistance; in particular, the verified genes CCL5, STAT1-α, STAT2 and GSTP1 may become potential biomarkers for predicting NPC response to radiotherapy.
Katriel, Jacob; Bauer, Michael; Springborg, Michael; McCarthy, Shane P; Thakkar, Ajit J
2007-07-14
Reparametrization of Wigner's correlation energy density functional yields a very close fit to the correlation energies of the helium isoelectronic sequence. However, a quite different reparametrization is required to obtain an equally close fit to the isoelectronic sequence of Hooke's atom. In an attempt to avoid having to reparametrize the functional for different choices of the one-body potential, we propose a parametrization that depends on global characteristics of the ground-state electron density as quantified by scale-invariant combinations of expectation values of local one-body operators. This should be viewed as an alternative to the density-gradient paradigm, allowing one to introduce the nonlocal dependence of the density functional on the density in a possibly more effective way. Encouraging results are obtained for two-electron systems with one-body potentials of the form r(zeta) with zeta=-12,+12,1, which span the range between the Coulomb potential (zeta=-1) and the Hooke potential (zeta=2).
Spin-orbit coupled two-electron Fermi gases of ytterbium atoms
Song, Bo; Zhang, Shanchao; Zou, Yueyang; Haciyev, Elnur; Huang, Wei; Liu, Xiong-Jun; Jo, Gyu-Boong
2016-01-01
We demonstrate the spin-orbit coupling (SOC) in a two-electron Fermi gas of $^{173}$Yb atoms by coupling two hyperfine ground states via the two-photon Raman transition. Due to the SU($N$) symmetry of the $^1$S$_0$ ground-state manifold which is insensitive to external magnetic field, an optical AC Stark effect is applied to split the ground spin states and separate an effective spin-1/2 subspace out from other hyperfine levels for the realization of SOC. With a momentum-dependent spin-orbit gap being suddenly opened by switching on the Raman transition, the dephasing of spin dynamics is observed, as a consequence of the momentum-dependent Rabi oscillations. Moreover, the momentum asymmetry of the spin-orbit coupled Fermi gas is also examined after projection onto the bare spin state and the corresponding momentum distribution is measured for different two-photon detuning. The realization of SOC for Yb fermions may open a new avenue to the study of novel spin-orbit physics with alkaline-earth-like atoms.
Two-electron and one-photon transitions in highly charged nickel-like ions
Institute of Scientific and Technical Information of China (English)
Xie Lu-You; Dong Chen-Zhong; Jiang Jun; Wan Jian-Jie; Yan Jun
2008-01-01
This paper calculates the transition wavelengths and probabilities of the two-electron and one-photon(TEOP) transition from the(38-11/24dj)J:1,2 to(3p-13/24s1/2)J=1 and the(3p-11/2481/2)J=1 to(3d-1j4dj1)J=1,2 for highly charged Ni-like ions with atomic number Z in the range 47≤Z≤92.In the calculations,the multi-configuration Dirac-Fock method and corresponding program packages GRASP92 and REOS99 were used,and the relativistic effects,correlation effects and relaxation effects were considered systematically.It is found that the TEOP transitions are very sensitive to the correlation of electrons,and the probabilities will be enhanced sharply in some special Z regions along the isoelectronic sequence.The present TEOP transition wavelengths are compared with the available data from some previous publications,good agreement is obtained.
Spin-orbit-coupled two-electron Fermi gases of ytterbium atoms
Song, Bo; He, Chengdong; Zhang, Shanchao; Hajiyev, Elnur; Huang, Wei; Liu, Xiong-Jun; Jo, Gyu-Boong
2016-12-01
We demonstrate all-optical implementation of spin-orbit coupling (SOC) in a two-electron Fermi gas of 173Yb atoms by coupling two hyperfine ground states with a narrow optical transition. Due to the SU (N ) symmetry of the S10 ground-state manifold which is insensitive to external magnetic fields, an optical ac Stark effect is applied to split the ground spin states, which exhibits a high stability compared with experiments on alkali-metal and lanthanide atoms, and separate out an effective spin-1/2 subspace from other hyperfine levels for the realization of SOC. The dephasing spin dynamics when a momentum-dependent spin-orbit gap is suddenly opened and the asymmetric momentum distribution of the spin-orbit-coupled Fermi gas are observed as a hallmark of SOC. The realization of all-optical SOC for ytterbium fermions should offer a route to a long-lived spin-orbit-coupled Fermi gas and greatly expand our capability of studying spin-orbit physics with alkaline-earth-metal-like atoms.
Lorenzo-Diaz, Fabian; Fernández-Lopez, Cris; Douarre, Pierre-Emmanuel; Baez-Ortega, Adrian; Flores, Carlos; Glaser, Philippe
2016-01-01
Streptococcus agalactiae or Group B Streptococcus (GBS) are opportunistic bacteria that can cause lethal sepsis in children and immuno-compromised patients. Their genome is a reservoir of mobile genetic elements that can be horizontally transferred. Among them, integrative and conjugative elements (ICEs) and the smaller integrative and mobilizable elements (IMEs) primarily reside in the bacterial chromosome, yet have the ability to be transferred between cells by conjugation. ICEs and IMEs are therefore a source of genetic variability that participates in the spread of antibiotic resistance. Although IMEs seem to be the most prevalent class of elements transferable by conjugation, they are poorly known. Here, we have studied a GBS-IME, termed IMESag-rpsI, which is widely distributed in GBS despite not carrying any apparent virulence trait. Analyses of 240 whole genomes showed that IMESag-rpsI is present in approximately 47% of the genomes, has a roughly constant size (approx. 9 kb) and is always integrated at a single location, the 3′-end of the gene encoding the ribosomal protein S9 (rpsI). Based on their genetic variation, several IMESag-rpsI types were defined (A–J) and classified in clonal complexes (CCs). CC1 was the most populated by IMESag-rpsI (more than 95%), mostly of type-A (71%). One CC1 strain (S. agalactiae HRC) was deep-sequenced to understand the rationale underlying type-A IMESag-rpsI enrichment in GBS. Thirteen open reading frames were identified, one of them encoding a protein (MobSag) belonging to the broadly distributed family of relaxases MOBV1. Protein MobSag was purified and, by a newly developed method, shown to cleave DNA at a specific dinucleotide. The S. agalactiae HRC-IMESag-rpsI is able to excise from the chromosome, as shown by the presence of circular intermediates, and it harbours a fully functional mobilization module. Further, the mobSag gene encoded by this mobile element is able to promote plasmid transfer among pneumococcal
Liu, Xiao-Hong; Ning, Guo-Ao; Huang, Lu-Yao; Zhao, Ya-Hui; Dong, Bo; Lu, Jian-Ping; Lin, Fu-Cheng
2016-08-09
Calpains are ubiquitous and well-conserved proteins that belong to the calcium-dependent, non-lysosomal cysteine protease family. In this study, 8 putative calpains were identified using Pfam domain analysis and BlastP searches in M. oryzae. Three single gene deletion mutants (ΔMocapn7, ΔMocapn9 and ΔMocapn14) and two double gene deletion mutants (ΔMocapn4ΔMocapn7 and ΔMocapn9ΔMocapn7) were obtained using the high-throughput gene knockout system. The calpain disruption mutants showed defects in colony characteristics, conidiation, sexual reproduction and cell wall integrity. The mycelia of the ΔMocapn7, ΔMocapn4ΔMocapn7 and ΔMocapn9ΔMocapn7 mutants showed reduced pathogenicity on rice and barley.
In vivo accuracy of two electronic foramen locators based on different operation systems.
Vasconcelos, Bruno Carvalho de; Araújo, Rebeca Bastos Rocha; Silva, Francisco Cláudio Fernandes Alves e; Luna-Cruz, Suyane Maria; Duarte, Marco Antonio Hungaro; Fernandes, Carlos Augusto de Oliveira
2014-01-01
The aim of this study was to compare in vivo the accuracy of two electronic foramen locators (EFLs) based on different operation systems - Root ZX and Propex II. Ten healthy adult patients needing premolar extractions due to orthodontic reasons participated in the study, providing a sample of 17 noncarious, non-restored, vital teeth (n= 24 canals). After coronal access preparation and cervical preflaring and prior to tooth extraction, the root canal length was measured alternating the two EFLs. All measurements were performed with K-files well fitted to the canal diameter at the level that each EFL indicated the apical foramen in their display (APEX or 0.0). The last K-file were fixed in place with cyanoacrylate, the tooth was extracted, and the apical 4 mm of each root were resected to measure the distance between the file tip and the apical foramen. The mean errors based on the absolute values of discrepancies were 0.30 ± 0.29 mm (Root ZX) and 0.32 ± 0.27 mm (Propex II). Analysis by the Wilcoxon test for paired samples showed no statistically significant differences between the electronic canal measurements performed with the EFLs (p=0.587). The apical foramen was accurately located in 75% (Root ZX) and 66.7% (Propex II) of the cases, considering a ±0.5 mm error margin, with no statistically significant difference by the chi-square test. Despite having different measurement mechanisms, both EFLs were capable of locating the apical foramen with high accuracy in vivo. Under the tested clinical conditions, Root ZX and Propex II displayed similar results.
Green, Jennifer C; Green, Malcolm L H; Parkin, Gerard
2012-12-07
Although compounds that feature 3-centre 2-electron (3c-2e) bonds are well known, there has been no previous effort to classify the interactions according to the number of electrons that each atom contributes to the bond, in a manner analogous to the classification of 2-centre 2-electron (2c-2e) bonds as either normal covalent or dative covalent. This article provides an extension to the Covalent Bond Classification (CBC) method by categorizing 3c-2e interactions according to whether (i) the two electrons are provided by one or by two atoms and (ii) the central bridging atom provides two, one, or zero electrons. Class I 3c-2e bonds are defined as those in which two atoms each contribute one electron to the 3-centre orbital, while Class II 3c-2e bonds are defined as systems in which the pair of electrons are provided by a single atom. Class I and Class II 3c-2e interactions can be denoted by structure-bonding representations that employ the "half-arrow" notation, which also provides a convenient means to determine the electron count at a metal centre. In contrast to other methods of electron counting, this approach provides a means to predict metal-metal bond orders that are in accord with theory. For example, compounds that feature symmetrically bridging carbonyl ligands do not necessarily have to be described as "ketone derivatives" because carbon monoxide can also serve as an electron pair donor to two metal centres. This bonding description also provides a simple means to rationalize the theoretical predictions of the absence of M-M bonds in molecules such as Fe(2)(CO)(9) and [CpFe(CO)(2)](2), which are widely misrepresented in textbooks as possessing M-M bonds.
Schmöckel, Sandra M; Lightfoot, Damien J; Razali, Rozaimi; Tester, Mark; Jarvis, David E
2017-01-01
Chenopodium quinoa (quinoa) is an emerging crop that produces nutritious grains with the potential to contribute to global food security. Quinoa can also grow on marginal lands, such as soils affected by high salinity. To identify candidate salt tolerance genes in the recently sequenced quinoa genome, we used a multifaceted approach integrating RNAseq analyses with comparative genomics and topology prediction. We identified 219 candidate genes by selecting those that were differentially expressed in response to salinity, were specific to or overrepresented in quinoa relative to other Amaranthaceae species, and had more than one predicted transmembrane domain. To determine whether these genes might underlie variation in salinity tolerance in quinoa and its close relatives, we compared the response to salinity stress in a panel of 21 Chenopodium accessions (14 C. quinoa, 5 C. berlandieri, and 2 C. hircinum). We found large variation in salinity tolerance, with one C. hircinum displaying the highest salinity tolerance. Using genome re-sequencing data from these accessions, we investigated single nucleotide polymorphisms and copy number variation (CNV) in the 219 candidate genes in accessions of contrasting salinity tolerance, and identified 15 genes that could contribute to the differences in salinity tolerance of these Chenopodium accessions.
Schmöckel, Sandra M.
2017-06-21
Chenopodium quinoa (quinoa) is an emerging crop that produces nutritious grains with the potential to contribute to global food security. Quinoa can also grow on marginal lands, such as soils affected by high salinity. To identify candidate salt tolerance genes in the recently sequenced quinoa genome, we used a multifaceted approach integrating RNAseq analyses with comparative genomics and topology prediction. We identified 219 candidate genes by selecting those that were differentially expressed in response to salinity, were specific to or overrepresented in quinoa relative to other Amaranthaceae species, and had more than one predicted transmembrane domain. To determine whether these genes might underlie variation in salinity tolerance in quinoa and its close relatives, we compared the response to salinity stress in a panel of 21 Chenopodium accessions (14 C. quinoa, 5 C. berlandieri, and 2 C. hircinum). We found large variation in salinity tolerance, with one C. hircinum displaying the highest salinity tolerance. Using genome re-sequencing data from these accessions, we investigated single nucleotide polymorphisms and copy number variation (CNV) in the 219 candidate genes in accessions of contrasting salinity tolerance, and identified 15 genes that could contribute to the differences in salinity tolerance of these Chenopodium accessions.
Grassi, Vincenzo M; Castagnola, Flaminia; Miscusi, Massimo; De-Giorgio, Fabio
2016-09-01
Rollover car accidents can be the result of forceful steering or hitting an obstacle that acts like a ramp. Mortality from this type of car accident is particularly high, especially when occupants are thrown out of the vehicle. We report a case of a 67-year-old man who died after a rollover accident that occurred when he was driving a car equipped with a glass moonroof. He was found inside his car with his safety belt correctly fastened and the roof shattered. At autopsy, a wide avulsion injury of the head was observed, which was associated with an atlanto-axial dislocation and full-thickness fracture of the cervical body and posterior facet joints of the seventh cervical vertebra. The data collected at the scene of the accident were integrated with the autopsy results to yield a forensic engineering reconstruction. This reconstruction elucidated the dynamics of the event and correctly ascribed the lesions observed at autopsy to the phases of the rollover. Afterward, an analysis of the scientific literature concerning rollover crash tests was conducted to understand why the driver sustained fatal injuries even though his seatbelt was properly fastened.
Chang, Chien-Chieh; Chen, Chia-Shyun
2002-06-01
A flowing partially penetrating well with infinitesimal well skin is a mixed boundary because a Cauchy condition is prescribed along the screen length and a Neumann condition of no flux is stipulated over the remaining unscreened part. An analytical approach based on the integral transform technique is developed to determine the Laplace domain solution for such a mixed boundary problem in a confined aquifer of finite thickness. First, the mixed boundary is changed into a homogeneous Neumann boundary by substituting the Cauchy condition with a Neumann condition in terms of well bore flux that varies along the screen length and is time dependent. Despite the well bore flux being unknown a priori, the modified model containing this homogeneous Neumann boundary can be solved with the Laplace and the finite Fourier cosine transforms. To determine well bore flux, screen length is discretized into a finite number of segments, to which the Cauchy condition is reinstated. This reinstatement also restores the relation between the original model and the solutions obtained. For a given time, the numerical inversion of the Laplace domain solution yields the drawdown distributions, well bore flux, and the well discharge. This analytical approach provides an alternative for dealing with the mixed boundary problems, especially when aquifer thickness is assumed to be finite.
Padhy, B
2016-01-01
The simple method outlined in our earlier paper [B.Padhy, Orissa Journal of Physics, vol.19, No.1, p.1, February 2012] has been utilized here for analytic evaluation of three different five-electron atomic integrals with integrands involving products of s Slater-type orbitals and exponentially correlated functions of the form $r_{ij} exp(-\\lambda_{ij} r_{ij})$. Only products of those $r_{ij}$'s which do not form a closed loop by themselves, are considered.
The case for synchrotron radiation studies of two-electron ions, atoms, and molecules at the ALS
Lubell, M. S.
1995-05-01
The theoretical description of two-electron systems has remained one of the most vexing problems in atomic physics since Bohr first introduced the concept of the quantized atom in 1913. Despite the diversity in approach, a degree of orthodoxy developed over the course of many years for characterizing and clasifying the discrete spectrum of two-electron states and for describing the features of the near-threshold double continuum. The last four years have seen this orthodoxy challenged both theoretically and experimentally. As a result, a strong need exists for additional experimental investigations of two-electron systems. We will first examine the long-held orthodox views and the recent challenges to them. We will then review the details and status of a new program at the Advanced Light Source (ALS) of Lawrence Berkeley Laboratory that has been developed by the NAU8 Collaboration to address this need.
Directory of Open Access Journals (Sweden)
Álvarez-Morales Ariel
2011-05-01
Full Text Available Abstract Background Pseudomonas syringae pv. phaseolicola, the causal agent of halo blight disease in beans, produces a toxin known as phaseolotoxin, in whose synthesis participate a group of genes organized within the genome in a region known as the "Pht cluster". This region, which is thought to have been acquired by horizontal gene transfer, includes 5 transcriptional units, two monocistronic (argK, phtL and three polycistronic (phtA, phtD, phtM, whose expression is temperature dependent. So far, the regulatory mechanisms involved in phaseolotoxin synthesis have not been elucidated and the only well-established fact is the requirement of low temperatures for its synthesis. In this work, we searched for regulatory proteins that could be involved in phaseolotoxin synthesis, focusing on the regulation of the phtD operon. Results In this study we identified the global regulator IHF (Integration Host Factor, which binds to the promoter region of the phtD operon, exerting a negative effect on the expression of this operon. This is the first regulatory protein identified as part of the phaseolotoxin synthesis system. Our findings suggest that the Pht cluster was similarly regulated in the ancestral cluster by IHF or similar protein, and integrated into the global regulatory mechanism of P. syringae pv. phaseolicola, after the horizontal gene transfer event by using the host IHF protein. Conclusion This study identifies the IHF protein as one element involved in the regulation of phaseolotoxin synthesis in P. syringae pv. phaseolicola NPS3121 and provides new insights into the regulatory mechanisms involved in phaseolotoxin production.
Liu, Ning; Ning, Guo-Ao; Liu, Xiao-Hong; Feng, Xiao-Xiao; Lu, Jian-Ping; Mao, Li-Juan; Su, Zhen-Zhu; Wang, Ying; Zhang, Chu-Long; Lin, Fu-Cheng
2016-11-01
The endophytic fungus Harpophora oryzae is a beneficial endosymbiont isolated from wild rice. H. oryzae can not only promote rice growth and biomass accumulation but also protect rice roots from invasion by its close relative Magnaporthe oryzae. Autophagy is a highly evolutionary conserved process from lower to higher eukaryotic organisms, and is involved in the maintenance of normal cell differentiation and development. In this study, we isolated a gene (HoATG5) which encodes an essential protein required for autophagy from the beneficial endophyte fungus H. oryzae. Using targeted gene replacement, a ΔHoATG5 mutant was generated and used to investigate the biological functions of autophagy in H. oryzae. We found that the autophagic process was blocked in the HoATG5 deletion mutant. The mutant showed increased vegetative growth and sporulation, and was sensitive to nutrient starvation. The ΔHoATG5 mutant lost its ability to penetrate and infect the wounded barley leaves. These results provide new knowledge to elaborate the molecular machinery of autophagy in endophytic fungi.
Piche, T; Barbara, G; Aubert, P; Bruley des Varannes, S; Dainese, R; Nano, J L; Cremon, C; Stanghellini, V; De Giorgio, R; Galmiche, J P; Neunlist, M
2009-02-01
Growing evidence suggests that patients with irritable bowel syndrome (IBS) have increased intestinal permeability. In addition, mucosal soluble mediators are involved in the pathophysiology of pain in IBS. We aimed to investigate (1) paracellular permeability in colonic biopsies of patients with IBS; and (2) the ability of soluble factors from colonic biopsies to reproduce these alterations in vitro. Paracellular permeability in colonic biopsies of healthy subjects and patients with IBS was measured by mounting the biopsies in Ussing chambers. Cleared supernatant (SUP) of the culture from colonic biopsies was collected and applied to Caco-2 cells for 48 h. Paracellular permeability and transepithelial resistance (TER) were evaluated. mRNA expression of the tight junction proteins, zonula occludens (ZO)-1 and occludin, was assessed in colonic biopsies. Abdominal pain was assessed using a validated questionnaire. Permeability of colonic biopsies was significantly higher in patients with IBS compared to healthy subjects. These changes were associated with significantly lower expression of ZO-1 mRNA in biopsies of IBS as compared to healthy subjects. Compared to healthy subjects, SUP of IBS markedly reduced TER and significantly increased permeability in Caco-2 cells. SUP of IBS patients induced a significant decrease of ZO-1 mRNA in Caco-2 as compared to healthy subjects. SUP-induced increased paracellular permeability correlated with the severity of abdominal pain. Our study shows that colonic soluble mediators are able to reproduce functional (permeability) and molecular (ZO-1 mRNA expression) alterations observed in IBS patients. These findings might pave the way both to identify novel biomarkers as well as new therapeutic targets in IBS.
Meier, Joseph; Kappadath, S Cheenu
2015-11-08
We characterized the energy response of personal dose equivalent (Hp(10) in mrem) and the contribution of backscatter to the readings of two electronic personal dosimeter (EPD) models with radionuclides commonly used in a nuclear medicine clinic. The EPD models characterized were the RADOS RAD-60R, and the SAIC PD-10i. The experimental setup and calculation of EPD energy response was based on ANSI/HPS N13.11-2009. Fifteen RAD-60R and 2 PD-10i units were irradiated using (99m)Tc, (131)I, and (18)F radionuclides with emission energies at 140 keV, 364 keV, and 511 keV, respectively. At each energy, the EPDs output in Hp(10) [mrem] were recorded with 15 inch thick PMMA to simulate backscatter form the torso. Simultaneous free-in-air exposure rate measurements were also performed using two Victoreen ionization survey meters to calculate the expected EPD Hp(10) values per ANSI/HPS N13.11-2009. The energy response was calculated by taking the ratio of the EPD Hp(10) readings with the expected Hp(10) readings and a two-tailed z-test was used to determine the significance of the ratio deviating away from unity. The contribution from backscatter was calculated by taking the ratio of the EPD Hp(10) readings with and without backscatter material. A paired, two-tailed t-test was used to determine the significance of change in EPD Hp(10) readings. The RAD-60R mean energy response at 140 keV was 0.85, and agreed to within 5% and 11% at 364 and 511 keV, respectively. The PD-10i mean energy response at 140 keV was 1.20, and agreed to within 5% at 364 and 511 keV, respectively. On average, in the presence of acrylic, RAD-60R values increased by 32%, 12%, and 14%, at 140, 364, and 511 keV, respectively; all increases were statistically significant. The PD-10i increased by 25%, 19%, and 10% at 140 keV, 364 keV, and 511 keV, respectively; however, only the 140 keV measurement was statistically significant. Although both EPD models performed within the manufacturers' specifications of
Modified Korteweg-de Vries solitons at supercritical densities in two-electron temperature plasmas
Verheest, Frank; Hereman, Willy A
2016-01-01
The supercritical composition of a plasma model with cold positive ions in the presence of a two-temperature electron population is investigated, initially by a reductive perturbation approach, under the combined requirements that there be neither quadratic nor cubic nonlinearities in the evolution equation. This leads to a unique choice for the set of compositional parameters and a modified Korteweg-de Vries equation (mKdV) with a quartic nonlinear term. The conclusions about its one-soliton solution and integrability will also be valid for more complicated plasma compositions. Only three polynomial conservation laws can be obtained. The mKdV equation with quartic nonlinearity is not completely integrable, thus precluding the existence of multi-soliton solutions. Next, the full Sagdeev pseudopotential method has been applied and this allows for a detailed comparison with the reductive perturbation results. This comparison shows that the mKdV solitons have slightly larger amplitudes and widths than those obta...
Directory of Open Access Journals (Sweden)
Chorpet esaenchai
2016-04-01
Full Text Available Plants survival depends on their ability to cope with multiple nutrient stresses that often occur simultaneously, such as the limited availability of essential elements inorganic phosphate (Pi, zinc (Zn and iron (Fe. Previous research has provided information on the genes involved in efforts by plants to maintain homeostasis when a single nutrient (Pi, Zn or Fe is depleted. Recent findings on nutritional stress suggest that plant growth capacity is influenced by a complex tripartite interaction between Pi, Zn and Fe homeostasis. However, despite its importance, how plants integrate multiple nutritional stimuli into complex developmental programs, and which genes are involved in this tripartite (Pi ZnFe interaction is still not clear. The aim of this study was to examine the physiological and molecular responses of rice (Oriza sativa L. to a combination of Pi, Zn and/or Fe deficiency stress conditions. Results showed that Fe deficiency had the most drastic single-nutrient effect on biomass, while the Zn deficiency-effect depended on the presence of Pi in the medium. Interestingly, the observed negative effect of Fe starvation was alleviated by concomitant Pi or PiZn depletion. Members of the OsPHO1 family showed a differential transcriptional regulation in response PiZnFe combinatory stress conditions. Particularly, the transcripts of the OsPHO1;1 sense and its natural antisense cis-NatPHO1;1 showed the highest accumulation under PiZn deficiency. In this condition, the Ospho1;1 mutants showed over-accumulation of Fe in roots compared to wild type plants. These data reveal coordination between pathways involved in Fe transport and PiZn signalling in rice which involves the OsPHO1; 1, and support the hypothesis of a genetic basis for Pi, Zn and Fe signalling interactions in plants.
DEFF Research Database (Denmark)
Olwig, Karen Fog
2011-01-01
After a long history dominated by out-migration, Denmark, Norway and Sweden have, in the past 50 years, become immigration societies. This article compares how these Scandinavian welfare societies have sought to incorporate immigrants and refugees into their national communities. It suggests that......, while the countries have adopted disparate policies and ideologies, differences in the actual treatment and attitudes towards immigrants and refugees in everyday life are less clear, due to parallel integration programmes based on strong similarities in the welfare systems and in cultural notions...... of equality in the three societies. Finally, it shows that family relations play a central role in immigrants’ and refugees’ establishment of a new life in the receiving societies, even though the welfare society takes on many of the social and economic functions of the family....
Directory of Open Access Journals (Sweden)
Jason Richard Yee
2015-02-01
Full Text Available In the present study, we used functional MRI in awake rats to investigate the pain response that accompanies intradermal injection of capsaicin into the hindpaw. To this end, we used BOLD imaging together with a 3D segmented, annotated rat atlas and computational analysis to identify the integrated neural circuits involved in capsaicin-induced pain. The specificity of the pain response to capsaicin was tested in a transgenic model that contains a biallelic deletion of the gene encoding for the transient receptor potential cation channel subfamily V member 1 (TRPV1. Capsaicin is an exogenous ligand for the TRPV1 receptor, and in wild-type rats, activated the putative pain neural circuit. In addition, capsaicin-treated wild-type rats exhibited activation in brain regions comprising the Papez circuit and habenular system, systems that play important roles in the integration of emotional information, and learning and memory of aversive information, respectively. As expected, capsaicin administration to TRPV1-KO rats failed to elicit the robust BOLD activation pattern observed in wild-type controls. However, the intradermal injection of formalin elicited a significant activation of the putative pain pathway as represented by such areas as the anterior cingulate, somatosensory cortex, parabrachial nucleus, and periaqueductal gray. Notably, comparison of neural responses to capsaicin in wild-type versus knock-out rats uncovered evidence that capsaicin may function in an antinociceptive capacity independent of TRPV1 signaling. Our data suggest that neuroimaging of pain in awake, conscious animals has the potential to inform the neurobiological basis of full and integrated perceptions of pain.
Adiabatic potential energy curves of long-range Rydberg molecules: Two-electron R-matrix approach
Tarana, Michal
2016-01-01
We introduce a computational method developed for study of long-range molecular Rydberg states of such systems that can be approximated by two electrons in a model potential of the atomic cores. Only diatomic molecules are considered. The method is based on a two-electron \\rmath approach inside a sphere centered on one of the atoms. The wave function is then connected to a Coulomb region outside the sphere via multichannel version of the Coulomb Green's function. This approach is put into a test by its application to a study of Rydberg states of the hydrogen molecule for internuclear distances $R$ from 20 to 400 bohrs and energies corresponding to $n$ from 3 to 22. The results are compared with previous quantum chemical calculations (lower quantum numbers $n$) and computations based on contact potential models (higher quantum numbers $n$).
Energy Technology Data Exchange (ETDEWEB)
Noguchi, Yoshifumi [Department of Physics, Graduate School of Engineering, Yokohama National University, 79-5 Tokiwadai, Hodogaya-ku, Yokohama 240-8501 (Japan); Computational Materials Science Center, National Institute for Materials Science, 1-2-1 Sengen, Tsukuba, Ibaraki 305-0047 (Japan)], E-mail: NOGUCHI.Yoshifumi@nims.go.jp; Ishii, Soh; Ohno, Kaoru [Department of Physics, Graduate School of Engineering, Yokohama National University, 79-5 Tokiwadai, Hodogaya-ku, Yokohama 240-8501 (Japan)
2007-05-15
Short-range electron correlation plays a very important role in small systems and significantly affects the double ionization energy (DIE) spectra and the two-electron distribution functions of a CO molecule, for example. In our calculations, the local density approximation (LDA) of the density functional theory is chosen as a starting point, the GW approximation (GWA) is performed in a next step, and finally the Bethe-Salpeter equation for the T-matrix, describing the particle-particle ladder diagrams up to the infinite order, is solved via the eigenvalue problem. The calculated DIE spectra, which are directly given by the eigenvalues, reflect the short-range electron correlation and are in good agreement with the experiment. We confirm that the Coulomb hole appears in the two-electron distribution function constructed from the eigenfunction.
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Mishra Pankaj K
2007-01-01
Full Text Available Abstract Background The glutamate synthase operon (gltBDF contributes to one of the two main pathways of ammonia assimilation in Escherichia coli. Of the seven most-global regulators, together affecting expression of about half of all E. coli genes, two were previously shown to exert direct, positive control on gltBDF transcription: Lrp and IHF. The involvement of Lrp is unusual in two respects: first, it is insensitive to the usual coregulator leucine, and second, Lrp binds more than 150 bp upstream of the transcription starting point. There was indirect evidence for involvement of a third global regulator, Crp. Given the physiological importance of gltBDF, and the potential opportunity to learn about integration of global regulatory signals, a combination of in vivo and in vitro approaches was used to investigate the involvement of additional regulatory proteins, and to determine their relative binding positions and potential interactions with one another and with RNA polymerase (RNAP. Results Crp and a more local regulator, ArgR, directly control gltBDF transcription, both acting negatively. Crp-cAMP binds a sequence centered at -65.5 relative to the transcript start. Mutation of conserved nucleotides in the Crp binding site abolishes the Crp-dependent repression. ArgR also binds to the gltBDF promoter region, upstream of the Lrp binding sites, and decreases transcription. RNAP only yields a defined DNAse I footprint under two tested conditions: in the presence of both Lrp and IHF, or in the presence of Crp-cAMP. The DNAse I footprint of RNAP in the presence of Lrp and IHF is altered by ArgR. Conclusion The involvement of nearly half of E. coli's most-global regulatory proteins in the control of gltBDF transcription is striking, but seems consistent with the central metabolic role of this operon. Determining the mechanisms of activation and repression for gltBDF was beyond the scope of this study. However the results are consistent with a
Electron transfer by excited benzoquinone anions: slow rates for two-electron transitions.
Zamadar, Matibur; Cook, Andrew R; Lewandowska-Andralojc, Anna; Holroyd, Richard; Jiang, Yan; Bikalis, Jin; Miller, John R
2013-09-05
Electron transfer (ET) rate constants from the lowest excited state of the radical anion of benzoquinone, BQ(-•)*, were measured in THF solution. Rate constants for bimolecular electron transfer reactions typically reach the diffusion-controlled limit when the free-energy change, ΔG°, reaches -0.3 eV. The rate constants for ET from BQ(-•)* are one-to-two decades smaller at this energy and do not reach the diffusion-controlled limit until -ΔG° is 1.5-2.0 eV. The rates are so slow probably because a second electron must also undergo a transition to make use of the energy of the excited state. Similarly, ET, from solvated electrons to neutral BQ to form the lowest excited state, is slow, while fast ET is observed at a higher excited state, which can be populated in a transition involving only one electron. A simple picture based on perturbation theory can roughly account for the control of electron transfer by the need for transition of a second electron. The picture also explains how extra driving force (-ΔG°) can restore fast rates of electron transfer.
Lim, Hwei Mian; Chee, Hengleng; Kandiah, Mirnalini; Shamsuddin, Khadijah; Jamaluddin, Jamilah; Nordin, Noranitamegat; Shuib, Rashidah
2003-09-01
This study was a cross-sectional survey conducted among 122 women workers employed in the electronics factories in the Ulu Klang Free Trade Zone (FTZ) and the Bangi FTZ, Selangor, Peninsular Malaysia. The purpose of the study was to examine the problem of overweight (>25.0 kg/m2) among this group of women, and factors (socio-demographic, work, exercise, and dietary) associated with overweight, and, to study the food intake pattern of the women in both the overweight and non-overweight groups. Data was collected using a set of questionnaires, while anthropometric measurements were obtained to calculate body mass index (BMI) and waist hip ratio (WHR). The results of the study indicated that 64.0% of the women were overweight (29.5% pre-obese, 34.5% obese). About one-tenth of the women (11.5%) had a WHR of above 0.85. From the bivariate analysis, it was found that women who were older, ever married, had lower educational level, had higher salary, not living in the hostel, involved in shiftwork, and trying to lose weight were more likely to be overweight. After adjusting for age, each of the above factors, except for educational level, remained significantly associated with overweight. Women's diet was found to be monotonous and lacking in variety as accessibility to and availability of a variety of food was a problem for them due to the nature of their work. They also had a sedentary lifestyle. Therefore, further research focusing on changing the poor dietary habits and sedentary lifestyle of the women workers is necessary to address the problem of overweight.
Taylor, Aidan J.; Zakai, Shadi A. I.; Kelly, David J.
2017-01-01
The outer membrane (OM) of Gram-negative pathogenic bacteria is a key structure in host–pathogen interactions that contains a plethora of proteins, performing a range of functions including adhesion, nutrient uptake, export of effectors and interaction with innate and adaptive components of the immune system. In addition, the OM can exclude drugs and thus contribute to antimicrobial resistance. The OM of the food-borne pathogen Campylobacter jejuni contains porins, adhesins and other virulence factors that must be specifically localized to this membrane, but the protein sorting mechanisms involved are only partially understood. In particular, chaperones are required to ferry OM proteins across the periplasm after they emerge from the Sec translocation system. The SurA-related chaperone PEB4 (Cj0596) is the only protein with a proven role in OM biogenesis and integrity in C. jejuni. In this work, we have constructed a set of isogenic deletion mutants in genes encoding both known and predicted chaperones (cj0596, cj0694, cj1069, cj1228c, and cj1289) using NCTC 11168H as the parental strain. These mutants were characterized using a range of assays to determine effects on growth, agglutination, biofilm formation, membrane permeability and hydrophobicity. We focused on Cj1289 and Cj0694, which our previous work suggested possessed both chaperone and peptidyl-proyl cis/trans isomerase (PPIase) domains. Mutants in either cj1289 or cj0694 showed growth defects, increased motility, agglutination and biofilm formation and severe OM permeability defects as measured by a lysozyme accessibility assay, that were comparable to those exhibited by the isogenic peb4 mutant. 2D-gel comparisons showed a general decrease in OM proteins in these mutants. We heterologously overproduced and purified Cj0694 and obtained evidence that this protein was an active PPIase, as judged by its acceleration of the refolding rate of reduced and alkylated ribonuclease T1 and that it also possessed
Coulomb Repulsion Effect in Two-electron Non-adiabatic Tunneling through a One-level redox Molecule
DEFF Research Database (Denmark)
Medvedev, Igor M.; Kuznetsov, Alexander M.; Ulstrup, Jens
2009-01-01
is representative of electrochemical scanning tunneling microscopy or a pair of electrochemical nanoscale electrodes. The two-electron transfer molecular system also represents redox molecules with three electrochemically accessible oxidation states, rather than only two states such as comprehensively studied...... conductance/bias voltage correlation can have up to four peaks even for a single-level redox molecule. The peak position, height, and width are determined by the oxidized and reduced states of both the ionization and affinity levels of the molecule and depend crucially on the Debye screening of the electric...
Becker, A; Faisal, F
2001-03-26
Recently observed momentum distribution of doubly charged recoil-ions of atoms produced by femtosecond infrared laser pulses is analyzed using the so-called intense-field many-body S-matrix theory. Observed characteristics of the momentum distributions, parallel and perpendicular to the polarization axis, are reproduced by the theory. It is shown that correlated energy-sharing between the two electrons in the intermediate state and their 'Volkov-dressing' in the final state, can explain the origin of these characteristics.
Chu, John C. K.; Dalton, Derek M.; Rovis, Tomislav
2015-01-01
We report a catalytic asymmetric synthesis of piperidines through [4+2] cycloaddition of 1-azadienes and nitroalkenes. The reaction uses earth abundant Zn as catalyst, and is highly diastereo- and regio-selective. A novel BOPA ligand (F-BOPA) confers high reactivity and enantioselectivity in the process. The presence of ortho substitution on the arenes adjacent to the bis(oxazolines) was found to be particularly impactful, due to limiting the undesired coordination of 1-azadiene to the Lewis ...
Institute of Scientific and Technical Information of China (English)
胡义镇; 安静仪; 蒋丽金
1994-01-01
In this study the spectroscopic characteristics of a water-soluble derivative of hypocrellin A (HA), 14-dehydroxy-15-deacetyl-hypocrellin A-13-sulfonate(13-SO3Na-DDHA),and its one- and two-electron reduction products have been investigated. From the changes in absorbance with pH it was observed that the two phenolic hydroxy groups at C-3 and C-10 positions of 13-SO3Na-DDHA or HA dissociated stepwise with increase of pH values. The pKa values for 13-SO3Na-DDHA and HA were determined using an effective method established in this study. Attempts were also made to use absorption and ESR spectroscopies to study the photoreduction of 13-SO3Na-DDHA. It was found that 13-SO3Na-DDHA was directly reduced to its two-electron reduction product in buffered aqueous solution (pH 7. 7). However, in DMF-buffer (1 :1/ v : v,pH 7. 7), it proceeded with one-electron reduction to generate its semiquinone radical anions. The semiquinone radical anions decayed according to second-order kinetics. indicating that the terminatio
Tarana, Michal; Čurík, Roman
2016-05-01
We introduce a computational method developed for study of long-range molecular Rydberg states of such systems that can be approximated by two electrons in a model potential of the atomic cores. The method is based on a two-electron R-matrix approach inside a sphere centered on one of the atoms. The wave function is then connected to a Coulomb region outside the sphere via a multichannel version of the Coulomb Green's function. This approach is applied to a study of Rydberg states of Rb2 for internuclear separations R from 40 to 320 bohrs and energies corresponding to n from 7 to 30. We report bound states associated with the low-lying 3Po resonance and with the virtual state of the rubidium atom that turn into ion-pair-like bound states in the Coulomb potential of the atomic Rydberg core. The results are compared with previous calculations based on single-electron models employing a zero-range contact-potential and short-range modele potential. Czech Science Foundation (Project No. P208/14-15989P).
Cleaves, Peter A; King, David M; Kefalidis, Christos E; Maron, Laurent; Tuna, Floriana; McInnes, Eric J L; McMaster, Jonathan; Lewis, William; Blake, Alexander J; Liddle, Stephen T
2014-09-22
Two-electron reductive carbonylation of the uranium(VI) nitride [U(Tren(TIPS))(N)] (2, Tren(TIPS)=N(CH2CH2NSiiPr3)3) with CO gave the uranium(IV) cyanate [U(Tren(TIPS))(NCO)] (3). KC8 reduction of 3 resulted in cyanate dissociation to give [U(Tren(TIPS))] (4) and KNCO, or cyanate retention in [U(Tren(TIPS))(NCO)][K(B15C5)2] (5, B15C5=benzo-15-crown-5 ether) with B15C5. Complexes 5 and 4 and KNCO were also prepared from CO and the uranium(V) nitride [{U(Tren(TIPS))(N)K}2] (6), with or without B15C5, respectively. Complex 5 can be prepared directly from CO and [U(Tren(TIPS))(N)][K(B15C5)2] (7). Notably, 7 reacts with CO much faster than 2. This unprecedented f-block reactivity was modeled theoretically, revealing nucleophilic attack of the π* orbital of CO by the nitride with activation energy barriers of 24.7 and 11.3 kcal mol(-1) for uranium(VI) and uranium(V), respectively. A remarkably simple two-step, two-electron cycle for the conversion of azide to nitride to cyanate using 4, NaN3 and CO is presented.
Directory of Open Access Journals (Sweden)
de Morais Marcos A
2011-08-01
Full Text Available Abstract Background Polyhexamethylene biguanide (PHMB is an antiseptic polymer that is mainly used for cleaning hospitals and pools and combating Acantamoeba infection. Its fungicide activity was recently shown by its lethal effect on yeasts that contaminate the industrial ethanol process, and on the PE-2 strain of Saccharomyces cerevisiae, one of the main fermenting yeasts in Brazil. This pointed to the need to know the molecular mechanism that lay behind the cell resistance to this compound. In this study, we examined the factors involved in PHMB-cell interaction and the mechanisms that respond to the damage caused by this interaction. To achieve this, two research strategies were employed: the expression of some genes by RT-qPCR and the analysis of mutant strains. Results Cell Wall integrity (CWI genes were induced in the PHMB-resistant Saccharomyces cerevisiae strain JP-1, although they are poorly expressed in the PHMB-sensitive Saccharomyces cerevisiae PE2 strain. This suggested that PHMB damages the glucan structure on the yeast cell wall. It was also confirmed by the observed sensitivity of the yeast deletion strains, Δslg1, Δrom2, Δmkk2, Δslt2, Δknr4, Δswi4 and Δswi4, which showed that the protein kinase C (PKC regulatory mechanism is involved in the response and resistance to PHMB. The sensitivity of the Δhog1 mutant was also observed. Furthermore, the cytotoxicity assay and gene expression analysis showed that the part played by YAP1 and CTT1 genes in cell resistance to PHMB is unrelated to oxidative stress response. Thus, we suggested that Yap1p can play a role in cell wall maintenance by controlling the expression of the CWI genes. Conclusion The PHMB treatment of the yeast cells activates the PKC1/Slt2 (CWI pathway. In addition, it is suggested that HOG1 and YAP1 can play a role in the regulation of CWI genes.
Serov, Vladislav V; Sergeeva, Tatiana A; Vinitsky, Sergue I
2012-01-01
A review of some recently developed methods of calculating multiple differential cross-sections of photoionization and electron impactionization of atoms and molecules having two active electrons is presented. The methods imply original approaches to calculating three-particle Coulomb wave functions. The external complex scaling method and the formalism of the Schroedinger equation with a source in the right-hand side are considered. Efficiency of the time-dependent approaches to the scattering problem, such as the paraxial approximation and the time-dependent scaling, is demonstrated. An original numerical method elaborated by the authors for solving the 6D Schroedinger equation for an atom with two active electrons, based on the Chang-Fano transformation and the discrete variable representation, is formulated. Basing on numerical simulations, the threshold behavior of angular distributions of two-electron photoionization of the negative hydrogen ion and helium atom, and multiple differential cross-sections ...
Directory of Open Access Journals (Sweden)
A. Rejo Jeice
2013-09-01
Full Text Available The combined effect of hydrostatic pressure and temperature on correlation energy in a triplet state of two electron spherical quantum dot with square well potential is computed. The result is presented taking GaAs dot as an example. Our result shows the correlation energies are inegative in the triplet state contrast to the singlet state ii it increases with increase in pressure iiifurther decreases due to the application of temperature iv it approaches zero as dot size approaches infinity and v it contribute 10% decrement in total confined energy to the narrow dots. All the calculations have been carried out with finite models and the results are compared with existing literature.
[Cu13 {S2 CN(n) Bu2 }6 (acetylide)4 ](+) : A Two-Electron Superatom.
Chakrahari, Kiran Kumarvarma; Liao, Jian-Hong; Kahlal, Samia; Liu, Yu-Chiao; Chiang, Ming-Hsi; Saillard, Jean-Yves; Liu, C W
2016-11-14
The first structurally characterized copper cluster with a Cu13 centered cuboctahedral arrangement, a model of the bulk copper fcc structure, was observed in [Cu13 (S2 CN(n) Bu2 )6 (C≡CR)4 ](PF6 ) (R=C(O)OMe, C6 H4 F) nanoclusters. Four of the eight triangular faces of the cuboctahedron are capped by acetylide groups in μ3 fashion, and each of the six square faces is bridged by a dithiolate ligand in μ2 ,μ2 fashion, which leads to a truncated tetrahedron of twelve sulfur atoms. DFT calculations are fully consistent with the description of these Cu13 clusters as two-electron superatoms, that is, a [Cu13 ](11+) core passivated by ten monoanionic ligands, with an a1 HOMO containing two 1S jellium electrons.
Role of two-electron processes in the excitation-ionization of lithium atoms by fast ion impact
Kirchner, T; Gulyás, L
2015-01-01
We study excitation and ionization in the 1.5 MeV/amu O$^{8+}$-Li collision system, which was the subject of a recent reaction-microscope-type experiment [Fischer \\textit{et al.}, Phys. Rev. Lett. \\textbf{109}, 113202 (2012)]. Starting from an independent-electron model based on determinantal wave functions and using single-electron basis generator method and continuum distorted-wave with eikonal initial-state calculations we show that pure single ionization of a lithium $K$-shell electron is too weak a process to explain the measured single differential cross section. Rather, our analysis suggests that two-electron excitation-ionization processes occur and have to be taken into account when comparing with the data. Good agreement is obtained only if we replace the independent-electron calculation by an independent-event model for one of the excitation-ionization processes and also take a shake-off process into account.
Shimada, Tetsuya; Kumagai, Akihiro; Funyu, Shigeaki; Takagi, Shinsuke; Masui, Dai; Nabetani, Yu; Tachibana, Hiroshi; Tryk, Donald A; Inoue, Haruo
2012-01-01
The reaction mechanism of the highly efficient (phi = 0.60), selective photochemical epoxidation of alkenes sensitized by CO-coordinated tetra(2,4,6-trimethyl)phenylporphyrinatoruthenium(II) (Ru(II)TMP(CO)), with water acting both as an electron and oxygen atom donor, was investigated. The steady-state light irradiation of the reaction mixture indicated the formation of the Ru(II)TMP (CO) cation radical under neutral conditions, which was effectively trapped by an hydroxide ion to regenerate the starting sensitizer. By means of a laser flash photolysis experiment, the formation of the cation radical as the primary process from the triplet excited state of Ru(II)TMP(CO) was clearly observed. Four kinds of transients were detected in completely different ranges of the delay time: the excited triplet state of Ru(II)TMP(CO) [delay time region reaction mechanism was revealed that involves RuTMP(CO) cation radical formation from the triplet excited state of the sensitizer, followed by attack of an hydroxide ion to form an hydroxyl-coordinated Ru-porphyrin (Intermediate [I]) and subsequent reaction with cyclohexene to form Intermediate [II]. The kinetics for each step of the successive processes was carefully analyzed and their rate constants were determined. The two-electron oxidation of water by one-photon irradiation, as revealed in the photochemical epoxidation, is proposed to be one of the more promising candidates to get through the bottleneck of water oxidation in artificial photosynthesis.
Energy Technology Data Exchange (ETDEWEB)
Giesbertz, Klaas J. H. [Theoretical Chemistry, Faculty of Exact Sciences, VU University, De Boelelaan 1083, 1081 HV Amsterdam (Netherlands); Leeuwen, Robert van [Department of Physics, Nanoscience Center, University of Jyväskylä, P.O. Box 35, 40014 Jyväskylä, Survontie 9, Jyväskylä (Finland)
2014-05-14
Electron correlations in molecules can be divided in short range dynamical correlations, long range Van der Waals type interactions, and near degeneracy static correlations. In this work, we analyze for a one-dimensional model of a two-electron system how these three types of correlations can be incorporated in a simple wave function of restricted functional form consisting of an orbital product multiplied by a single correlation function f (r{sub 12}) depending on the interelectronic distance r{sub 12}. Since the three types of correlations mentioned lead to different signatures in terms of the natural orbital (NO) amplitudes in two-electron systems, we make an analysis of the wave function in terms of the NO amplitudes for a model system of a diatomic molecule. In our numerical implementation, we fully optimize the orbitals and the correlation function on a spatial grid without restrictions on their functional form. Due to this particular form of the wave function, we can prove that none of the amplitudes vanishes and moreover that it displays a distinct sign pattern and a series of avoided crossings as a function of the bond distance in agreement with the exact solution. This shows that the wave function ansatz correctly incorporates the long range Van der Waals interactions. We further show that the approximate wave function gives an excellent binding curve and is able to describe static correlations. We show that in order to do this the correlation function f (r{sub 12}) needs to diverge for large r{sub 12} at large internuclear distances while for shorter bond distances it increases as a function of r{sub 12} to a maximum value after which it decays exponentially. We further give a physical interpretation of this behavior.
Tao, Amy R; Onono, Maricianah; Baum, Sarah; Grossman, Daniel; Steinfeld, Rachel; Cohen, Craig R; Bukusi, Elizabeth A; Newmann, Sara J
2015-01-01
Integration of family planning (FP) services into HIV care and increasing male partner involvement in FP are being explored as strategies to reduce unmet need for contraception. Providers' views can give valuable insight into current FP care. We evaluated the perspectives of HIV care providers working at HIV clinics in Nyanza Province, Kenya, on male partner involvement in FP. This qualitative study was part of a cluster-randomized controlled trial evaluating the impact of integrating FP into HIV services on contraceptive prevalence among HIV-positive patients in Nyanza Province, Kenya. Thirty individual interviews were conducted among health-care workers at 11 HIV care facilities in Nyanza Province, Kenya. Interviews were conducted from integrated and control sites one year after implementation of FP/HIV integration. Data were transcribed and analyzed using grounded theory methods and ATLAS-ti. Providers supported male partner inclusion when choosing FP and emphasized that decisions should be made collaboratively. Providers believed that men have traditionally played a prohibitive role in FP but identified several benefits to partner involvement in FP decision-making including: reducing relationship conflicts, improving FP knowledge and contraceptive continuation, and increasing partner cohesion. Providers suggested that integrated FP/HIV services facilitate male partner involvement in FP decision-making since HIV-positive men are already established patients in HIV clinics. Some providers stated that women had a right to choose and start FP alone if their partners did not agree with using FP. Integrated FP services may be a useful strategy to help increase male participation to reduce the unmet FP need in sub-Saharan Africa. It is important to determine effective ways to engage male partners in FP, without impinging upon women's autonomy and reproductive rights.
Anusevicius, Zilvinas; Miseviciene, Lina; Medina, Milagros; Martinez-Julvez, Marta; Gomez-Moreno, Carlos; Cenas, Narimantas
2005-05-15
Flavoenzymes may reduce quinones in a single-electron, mixed single- and two-electron, and two-electron way. The mechanisms of two-electron reduction of quinones are insufficiently understood. To get an insight into the role of flavin semiquinone stability in the regulation of single- vs. two-electron reduction of quinones, we studied the reactions of wild type Anabaena ferredoxin:NADP(+)reductase (FNR) with 48% FAD semiquinone (FADH*) stabilized at the equilibrium (pH 7.0), and its Glu301Ala mutant (8% FADH* at the equilibrium). We found that Glu301Ala substitution does not change the quinone substrate specificity of FNR. However, it confers the mixed single- and two-electron mechanism of quinone reduction (50% single-electron flux), whereas the wild type FNR reduces quinones in a single-electron way. During the oxidation of fully reduced wild type FNR by tetramethyl-1,4-benzoquinone, the first electron transfer (formation of FADH*) is about 40 times faster than the second one (oxidation of FADH*). In contrast, the first and second electron transfer proceeded at similar rates in Glu301Ala FNR. Thus, the change in the quinone reduction mechanism may be explained by the relative increase in the rate of second electron transfer. This enabled us to propose the unified scheme of single-, two- and mixed single- and two-electron reduction of quinones by flavoenzymes with the central role of the stability of flavin/quinone ion-radical pair.
Rehman, Momin A.; Mishra, M. K.
2016-01-01
The ion-acoustic solitons in collisionless plasma consisting of warm adiabatic ions, isothermal positrons, and two temperature distribution of electrons have been studied. Using reductive perturbation method, Korteweg-de Vries (K-dV), the modified K-dV (m-KdV), and Gardner equations are derived for the system. The soliton solution of the Gardner equation is discussed in detail. It is found that for a given set of parameter values, there exists a critical value of β=Tc/Th, (ratio of cold to hot electron temperature) below which only rarefactive KdV solitons exist and above it compressive KdV solitons exist. At the critical value of β, both compressive and rarefactive m-KdV solitons co-exist. We have also investigated the soliton in the parametric regime where the KdV equation is not valid to study soliton solution. In this region, it is found that below the critical concentration the system supports rarefactive Gardner solitons and above it compressive Gardner solitons are found. The effects of temperature ratio of two-electron species, cold electron concentration, positron concentration on the characteristics of solitons are also discussed.
Energy Technology Data Exchange (ETDEWEB)
Brics, Martins; Kapoor, Varun; Bauer, Dieter [Institut fuer Physik, Universitaet Rostock, 18051 Rostock (Germany)
2013-07-01
Time-dependent density functional theory (TDDFT) with known and practicable exchange-correlation potentials does not capture highly correlated electron dynamics such as single-photon double ionization, autoionization, or nonsequential ionization. Time-dependent reduced density matrix functional theory (TDRDMFT) may remedy these problems. The key ingredients in TDRDMFT are the natural orbitals (NOs), i.e., the eigenfunctions of the one-body reduced density matrix (1-RDM), and the occupation numbers (OCs), i.e., the respective eigenvalues. The two-body reduced density matrix (2-RDM) is then expanded in NOs, and equations of motion for the NOs can be derived. If the expansion coefficients of the 2-RDM were known exactly, the problem at hand would be solved. In practice, approximations have to be made. We study the prospects of TDRDMFT following a top-down approach. We solve the exact two-electron time-dependent Schroedinger equation for a model Helium atom in intense laser fields in order to study highly correlated phenomena such as the population of autoionizing states or single-photon double ionization. From the exact wave function we calculate the exact NOs, OCs, the exact expansion coefficients of the 2-RDM, and the exact potentials in the equations of motion. In that way we can identify how many NOs and which level of approximations are necessary to capture such phenomena.
Ezra S Simon
2008-01-01
This study was conducted in Ghana to investigate, (1) factors that predict parental involvement, (2) the relationship between parental home and school involvement and the educational achievement of adolescents, (3) the relationship between parental authoritativeness and the educational achievement of adolescent students, (4) parental involvement serving as a mediator between their authoritativeness and the educational achievement of the students, and (5) whether parental involvement decreases...
Gumberidze, A; Stöhlker, Th; Banaś, D; Beckert, K; Beller, P; Beyer, H F; Bosch, F; Cai, X; Hagmann, S; Kozhuharov, C; Liesen, D; Nolden, F; Ma, X; Mokler, P H; Orsić-Muthig, A; Steck, M; Sierpowski, D; Tashenov, S; Warczak, A; Zou, Y
2004-05-21
Radiative recombination transitions into the ground state of cooled bare and hydrogenlike uranium ions were measured at the storage ring ESR. By comparing the corresponding x-ray centroid energies, this technique allows for a direct measurement of the electron-electron contribution to the ionization potential in the heaviest He-like ions. For the two-electron contribution to the ionization potential of He-like uranium we obtain a value of 2248+/-9 eV. This represents the most accurate determination of two-electron effects in the domain of high-Z He-like ions, and the accuracy reaches already the size of the specific two-electron radiative QED corrections.
Banerji, N.; Hayes, S. C.; Knorr, Fritz J.; Melamen, Deborah J.; Mchale, Jeanne L.; Marchioro, Arianna; Moser, Jacques-Edouard
2014-01-01
The plant pigment betanin is investigated as a dye-sensitizer on TiO2 with regard to its potential to undergo two- electron oxidation following one-photon excitation. Electrochemical, spectroelectrochemical and transient absorption measurements provide evidence for two-electron proton-coupled photo-oxidation leading to a quinone methide interme- diate which rearranges to 2-decarboxy-2,3-dehydrobetanin. Time-resolved spectroscopy measurements of betanin on nanocrystalline TiO2 and ZrO2 films w...
Knorr, Fritz J.; Malamen, Deborah J.; Mchale, Jeanne L.; Marchioro, Arianna; Moser, Jacques-Edouard
2014-01-01
The plant pigment betanin is investigated as a dye-sensitizer on TiO2 with regard to its potential to undergo two-electron oxidation following one-photon excitation. Electrochemical, spectroelectrochemical and transient absorption measurements provide evidence for two-electron proton-coupled photo-oxidation leading to a quinone methide intermediate which rearranges to 2-decarboxy-2,3-dehydrobetanin. Time-resolved spectroscopy measurements of betanin on nanocrystalline TiO2 and ZrO2 films were...
Nivillac, Nicole M I; Wasal, Karanvir; Villani, Daniela F; Naydenova, Zlatina; Hanna, W J Brad; Coe, Imogen R
2009-10-01
Human Equilibrative Nucleoside Transporter 1 (hENT1) is an integral membrane protein that transports nucleosides and analog drugs across cellular membranes. Very little is known about intracellular processing and localization of hENT1. Here we show that disruption of a highly conserved triplet (PWN) near the N-terminus, or the last eight C-terminal residues (two hydrophobic triplets separated by a positive arginine) result in loss of plasma membrane localization and/or transport function. To understand the role of specific residues within these regions, we studied the localization patterns of N- or C-terminal deletion and/or substitution mutants of GFP-hENT1 using confocal microscopy. Quantification of GFP-hENT1 (mutant and wildtype) protein at the plasma membrane was conducted using nitrobenzylthioinosine (NBTI) binding. Functionality of the GFP-hENT1 mutants was determined by heterologous expression in Xenopus laevis oocytes followed by measurement of uridine uptake. Mutation of the proline within the PWN motif disrupts plasma membrane localization. C-terminal mutations (primarily within the hydrophobic triplets) lead to hENT1 retention within the cell (e.g. in the ER). Some mutants still localize to the plasma membrane but show reduced transport activity. These data suggest that these two regions contribute to the structural integrity and thus correct processing and function of hENT1.
Directory of Open Access Journals (Sweden)
Jean-Francois eBRIAT
2015-04-01
Full Text Available Phosphate and sulfate are essential macro-elements for plant growth and development, and deficiencies in these mineral elements alter many metabolic functions. Nutritional constraints are not restricted to macro-elements. Essential metals such as zinc and iron have their homeostasis strictly genetically controlled, and deficiency or excess of these micro-elements can generate major physiological disorders, also impacting plant growth and development. Phosphate and sulfate on one hand, and zinc and iron on the other hand, are known to interact. These interactions have been partly described at the molecular and physiological levels, and are reviewed here. Furthermore the two macro-elements phosphate and sulfate not only interact between themselves but also influence zinc and iron nutrition. These intricated nutritional cross-talks are presented. The responses of plants to phosphorus, sulfur, zinc or iron deficiencies have been widely studied considering each element separately, and some molecular actors of these regulations have been characterized in detail. Although some scarce reports have started to examine the interaction of these mineral elements two by two, a more complex analysis of the interactions and cross-talks between the signaling pathways integrating the homeostasis of these various elements is still lacking. However, a MYB-like transcription factor, PHOSPHATE STARVATION RESPONSE 1 (PHR1, emerges as a common regulator of phosphate, sulfate, zinc and iron homeostasis, and its role as a potential general integrator for the control of mineral nutrition is discussed.
Lesiuk, Michał; Musiał, Monika; Jeziorski, Bogumił; Moszynski, Robert
2014-01-01
In this paper we present results of ab-initio calculations for the beryllium dimer with basis set of Slater-type orbitals (STOs). Nonrelativistic interaction energy of the system is determined using the frozen-core full configuration interaction calculations combined with high-level coupled cluster correction for inner-shell effects. Newly developed STOs basis sets, ranging in quality from double to sextuple zeta, are used in these computations. Principles of their construction are discussed and several atomic benchmarks are presented. Relativistic effects of order ${\\alpha}^2$ are calculated perturbatively by using the Breit-Pauli Hamiltonian and are found to be significant. We also estimate the leading-order QED effects. Influence of the adiabatic correction is found to be negligible. Finally, the interaction energy of the beryllium dimer is determined to be 929.0$\\,\\pm\\,$1.9 $cm^{-1}$, in a very good agreement with the recent experimental value. The results presented here appear to be the most accurate ab-...
Energy Technology Data Exchange (ETDEWEB)
Lappin, A.G.; Osvath, P.; Baral, S.
1987-09-23
The kinetics and mechanism of the two-electron oxidation of the sexidentate bis(oxime-imine) complex of nickel(II), (Ni/sup II/L) (I), by bromine have been investigated in bromide ion media over the pH range 3.1-7.6 at 25/sup 0/C and 1.0 M ionic strength. In the presence of an excess of bromine or nickel(II), oxidation is monophasic, and the initial product is (Ni/sup IV/L)/sup 2 +/, a formal nickel(IV) species that undergoes subsequent reactions to give an unknown oxidation product with excess bromine at pH > 6 or to give (Ni/sup III/L)/sup +/ by comproportionation with excess nickel(II) at pH > 5. The sole kinetically important oxidant is Br/sub 2/, and second-order rate constants for reaction of (Ni/sup II/L) and its protonated form (Ni/sup II/LH)/sup +/ are 2.1 x 10/sup 7/ and 7.1 x 10/sup 5/ M/sup -1/ s/sup -1/, respectively. These rate constants are in line with a rate-determining single-electron-transfer reaction, and the proposed mechanism involves formation of a transient ion pair (Ni/sup III/L/sup +/,Br/sub 2//sup -/ in which the rate of subsequent electron transfer is comparable with the rate of ion-pair dissociation. In addition, the pulse-radiolysis technique has been used to investigate the reactions of nickel(II) with Br/sub 2//sup -/ to give (Ni/sup III/L)/sup +/, and rate constants for (Ni/sup II/L) and (Ni/sup II/LH)/sup +/ are 8.5 x 10/sup 8/ and 2.7 x 10/sup 8/ M/sup -1/ S/sup -1/, respectively, at 21/sup 0/C. 34 references, 3 figures, 3 tables.
Rubio-Araiz, Ana; Perez-Hernandez, Mercedes; Urrutia, Andrés; Porcu, Francesca; Borcel, Erika; Gutierrez-Lopez, Maria Dolores; O'Shea, Esther; Colado, Maria Isabel
2014-08-01
The recreational drug 3,4-methylenedioxymethamphetamine (MDMA; 'ecstasy') produces a neuro-inflammatory response in rats characterized by an increase in microglial activation and IL-1β levels. The integrity of the blood-brain barrier (BBB) is important in preserving the homeostasis of the brain and has been shown to be affected by neuro-inflammatory processes. We aimed to study the effect of a single dose of MDMA on the activity of metalloproteinases (MMPs), expression of extracellular matrix proteins, BBB leakage and the role of the ionotropic purinergic receptor P2X7 (P2X7R) in the changes induced by the drug. Adult male Dark Agouti rats were treated with MDMA (10 mg/kg, i.p.) and killed at several time-points in order to evaluate MMP-9 and MMP-3 activity in the hippocampus and laminin and collagen-IV expression and IgG extravasation in the dentate gyrus. Microglial activation, P2X7R expression and localization were also determined in the dentate gyrus. Separate groups were treated with MDMA and the P2X7R antagonists Brilliant Blue G (BBG; 50 mg/kg, i.p.) or A-438079 (30 mg/kg, i.p.). MDMA increased MMP-3 and MMP-9 activity, reduced laminin and collagen-IV expression and increased IgG immunoreactivity. In addition, MDMA increased microglial activation and P2X7R immunoreactivity in these cells. BBG suppressed the increase in MMP-9 and MMP-3 activity, prevented basal lamina degradation and IgG extravasation into the brain parenchyma. A-438079 also prevented the MDMA-induced reduction in laminin and collagen-IV immunoreactivity. These results indicate that MDMA alters BBB permeability through an early P2X7R-mediated event, which in turn leads to enhancement of MMP-9 and MMP-3 activity and degradation of extracellular matrix.
Directory of Open Access Journals (Sweden)
Karl-Josef Dietz
2012-05-01
Full Text Available Transcription factors of the APETALA 2/Ethylene Response Factor (AP2/ERF-family have been implicated in diverse processes during development, stress acclimation and retrograde signaling. Fifty-three leaf-expressed AP2/ERFs were screened for their transcriptional response to abscisic acid (ABA, 3-(3,4-dichlorophenyl-1,1-dimethylurea (DCMU, methylviologen (MV, sucrose and high or low light, respectively, and revealed high reactivity to these effectors. Six of them (AP2-2, ARF14, CEJ1, ERF8, ERF11, RAP2.5 were selected for combinatorial response analysis to ABA, DCMU and high light. Additive, synergistic and antagonistic effects demonstrated that these transcription factors are components of multiple signaling pathways. AP2-2 (At1g79700 was subjected to an in depth study. AP2-2 transcripts were high under conditions linked to limited carbohydrate availability and stress and down-regulated in extended light phase, high light or in the presence of sugar. ap2-2 knock out plants had unchanged metabolite profiles and transcript levels of co-expressed genes in extended darkness. However, ap2-2 revealed more efficient germination and faster early growth under high sugar, osmotic or salinity stress, but the difference was abolished in the absence of sugar or during subsequent growth. It is suggested that AP2-2 is involved in mediating starvation-related and hormonal signals.
Wang, Bei; Gan, Zhen; Wang, Zhongliang; Yu, Dapeng; Lin, Ziwei; Lu, Yishan; Wu, Zaohe; Jian, Jichang
2017-02-01
MicroRNAs (miRNAs) are a class of noncoding RNA molecules and play important roles in a wide spectrum of biological processes, including in immune response. Recent years have witnessed considerable amount of research interest in studies on miRNA-mediated modulation gene function during neuroinflammation. Here, we evaluated Streptococcus agalactiae infected tilapia (Oreochromis niloticus) brain for the expression profile of miRNAs, potential functions and their correlation with genes involved in inflammatory pathways. A total of 1981 miRNAs were identified, including in 486 miRNAs which have homologues in the currently available databases and 1945 novel miRNAs. The expression levels of 547 miRNAs were significantly altered at 6 h-48 h post-bacterial infection, and these miRNAs were therefore classified as differentially expressed tilapia miRNAs. Real-time PCR were implemented for 14 miRNAs co-expressed in five samples, and agreement was confirmed between the high-throughput sequencing and real-time PCR data. For the 486 differentially expressed miRNAs target 41,820 genes. GO and KEGG enrichment analysis revealed that some target genes of miRNAs were grouped mainly into the categories of apoptotic, signal pathwayand immune response. This is the first report of comprehensive identification of teleost miRNAs being differentially regulated in brain in normal conditions relating to bacterial infection. Copyright © 2016 Elsevier Ltd. All rights reserved.
Hammell, Christopher M; Karp, Xantha; Ambros, Victor
2009-11-03
Animal development is remarkably robust; cell fates are specified with spatial and temporal precision despite physiological and environmental contingencies. Favorable conditions cause Caenorhabditis elegans to develop rapidly through four larval stages (L1-L4) to the reproductive adult. In unfavorable conditions, L2 larvae can enter the developmentally quiescent, stress-resistant dauer larva stage, enabling them to survive for prolonged periods before completing development. A specific progression of cell division and differentiation events occurs with fidelity during the larval stages, regardless of whether an animal undergoes continuous or dauer-interrupted development. The temporal patterning of developmental events is controlled by the heterochronic genes, whose products include microRNAs (miRNAs) and regulatory proteins. One of these proteins, the DAF-12 nuclear hormone receptor, modulates the transcription of certain let-7-family miRNAs, and also mediates the choice between the continuous vs. dauer-interrupted life history. Here, we report a complex feedback loop between DAF-12 and the let-7-family miRNAs involving both the repression of DAF-12 by let-7-family miRNAs and the ligand-modulated transcriptional activation and repression of the let-7-Fam miRNAs by DAF-12. We propose that this feedback loop functions to ensure robustness of cell fate decisions and to coordinate cell fate with developmental arrest.
Directory of Open Access Journals (Sweden)
Editorial Office
1979-09-01
Full Text Available Community involvement is the main theme of Health Year. Governments have a responsibility for the health of their people, and in this country under the present 3-tier system of government, the responsibility for the rendering of health services is divided between central, provincial and local government. However, under our democratic system, all people have the right to, and it is indeed their duty, to participate individually and collectively in the planning and implementation of services to meet their health needs. Ultimately, through involvement of individuals, families and communities, greater self-reliance is achieved leading to greater responsibility being assumed by people for their own health.
Directory of Open Access Journals (Sweden)
Jinhua Jiang
Full Text Available Type 2C protein phosphatases (PP2Cs play important roles in regulating many biological processes in eukaryotes. Currently, little is known about functions of PP2Cs in filamentous fungi. The causal agent of wheat head blight, Fusarium graminearum, contains seven putative PP2C genes, FgPTC1, -3, -5, -5R, -6, -7 and -7R. In order to investigate roles of these PP2Cs, we constructed deletion mutants for all seven PP2C genes in this study. The FgPTC3 deletion mutant (ΔFgPtc3-8 exhibited reduced aerial hyphae formation and deoxynivalenol (DON production, but increased production of conidia. The mutant showed increased resistance to osmotic stress and cell wall-damaging agents on potato dextrose agar plates. Pathogencity assays showed that ΔFgPtc3-8 is unable to infect flowering wheat head. All of the defects were restored when ΔFgPtc3-8 was complemented with the wild-type FgPTC3 gene. Additionally, the FgPTC3 partially rescued growth defect of a yeast PTC1 deletion mutant under various stress conditions. Ultrastructural and histochemical analyses showed that conidia of ΔFgPtc3-8 contained an unusually high number of large lipid droplets. Furthermore, the mutant accumulated a higher basal level of glycerol than the wild-type progenitor. Quantitative real-time PCR assays showed that basal expression of FgOS2, FgSLT2 and FgMKK1 in the mutant was significantly higher than that in the wild-type strain. Serial analysis of gene expression in ΔFgPtc3-8 revealed that FgPTC3 is associated with various metabolic pathways. In contrast to the FgPTC3 mutant, the deletion mutants of FgPTC1, FgPTC5, FgPTC5R, FgPTC6, FgPTC7 or FgPTC7R did not show aberrant phenotypic features when grown on PDA medium or inoculated on wheat head. These results indicate FgPtc3 is the key PP2C that plays a critical role in a variety of cellular and biological functions, including cell wall integrity, lipid and secondary metabolisms, and virulence in F. graminearum.
Energy Technology Data Exchange (ETDEWEB)
Amovilli, C., E-mail: amovilli@dcci.unipi.it [Dipartimento di Chimica e Chimica Industriale, Università di Pisa, Via Risorgimento 35, 56126 Pisa (Italy); March, N.H. [Department of Physics, University of Antwerp, Antwerp (Belgium); University of Oxford, Oxford (United Kingdom)
2014-05-01
Though density functional theory is already developed in useful practical numerical forms, no explicit simple ground-state energy density functional exists. Here, towards establishing such a theory, we present the ground-state energy of the Crandall et al.'s two-electron spin-compensated model atom in terms of ∇{sup 2}ρ(r)/ρ(r) evaluated at r=0, where ρ(r) is the electron density.
Amovilli, C.; March, N. H.
2014-05-01
Though density functional theory is already developed in useful practical numerical forms, no explicit simple ground-state energy density functional exists. Here, towards establishing such a theory, we present the ground-state energy of the Crandall et al.'s two-electron spin-compensated model atom in terms of ∇2ρ(r)/ρ(r) evaluated at r=0, where ρ(r) is the electron density.
Energy Technology Data Exchange (ETDEWEB)
March, N.H
2002-12-30
The first-order density matrix {gamma}(r{sub 1},r{sub 2}) for the ground-state of a model two-electron atom is explicitly constructed from the electron density {rho}(r). The model has harmonic confinement plus interparticle harmonic interactions. {gamma}(r{sub 1},r{sub 2}) and {rho}(r) are related non-locally, even though no density gradients and no quadratures appear.
Aratani, Yusuke; Suenobu, Tomoyoshi; Ohkubo, Kei; Yamada, Yusuke; Fukuzumi, Shunichi
2017-03-25
The photocatalytic production of hydrogen peroxide from water and dioxygen under visible light irradiation was made possible by using polymeric cyano-bridged heteronuclear metal complexes (M(II)[Ru(II)(CN)4(bpy)]; M(II) = Ni(II), Fe(II) and Mn(II)), where the photocatalytic two-electron reduction of O2 and water oxidation were catalysed by the Ru and M(II) moieties, respectively.
Certain integrals involving logarithmic and exponential functions
Directory of Open Access Journals (Sweden)
M. Aslam Chaudhry
1994-01-01
Full Text Available In this paper we have evaluated the integrals∫0∞xn−1lnxexp(−ax−bx−1dxand∫0∞xn−2(ax2−b(lnx2exp(−ax−bx−1dxfor all n=1,2,3,…. Some applications of the results are discussed and an open problem is posed.
Zhang, Min; E, Wenbo; Ohkubo, Kei; Sanchez-Garcia, David; Yoon, Dae-Wi; Sessler, Jonathan L; Fukuzumi, Shunichi; Kadish, Karl M
2008-02-21
Electron-transfer interconversion between the four-electron oxidized form of a quaterpyrrole (abbreviated as P4 for four pyrroles) and the two-electron oxidized form (P4H2) as well as between P4H2 and its fully reduced form (P4H4) bearing analogous substituents in the alpha- and beta-pyrrolic positions was studied by means of cyclic voltammetry and UV-visible spectroelectrochemistry combined with ESR and laser flash photolysis measurements. The two-electron oxidized form, P4H2, acts as both an electron donor and an electron acceptor. The radical cation (P4H2*+) and radical anion (P4H2*-) are both produced by photoinduced electron transfer from dimeric 1-benzyl-1,4-dihydronicotinamide to P4H2, whereas the cation radical form of the compound is also produced by electron-transfer oxidation of P4H2 with [Ru(bpy)3]3+. The ESR spectra of P4H2*+ and P4H2*- were recorded at low temperature and exhibit spin delocalization over all four pyrrole units. Thus, the two-electron oxidized form of the quaterpyrrole (P4H2) displays redox and electronic features analogous to those seen in the case of porphyrins and may be considered as a simple, open-chain model of this well-studied tetrapyrrolic macrocycle. The dynamics of deprotonation from P4H2*+ and disproportionation of P4H2 were examined by laser flash photolysis measurements of photoinduced electron-transfer oxidation and reduction of P4H2, respectively.
Mazziotti, David A
2016-10-07
A central challenge of physics is the computation of strongly correlated quantum systems. The past ten years have witnessed the development and application of the variational calculation of the two-electron reduced density matrix (2-RDM) without the wave function. In this Letter we present an orders-of-magnitude improvement in the accuracy of 2-RDM calculations without an increase in their computational cost. The advance is based on a low-rank, dual formulation of an important constraint on the 2-RDM, the T2 condition. Calculations are presented for metallic chains and a cadmium-selenide dimer. The low-scaling T2 condition will have significant applications in atomic and molecular, condensed-matter, and nuclear physics.
Mazziotti, David A.
2016-10-01
A central challenge of physics is the computation of strongly correlated quantum systems. The past ten years have witnessed the development and application of the variational calculation of the two-electron reduced density matrix (2-RDM) without the wave function. In this Letter we present an orders-of-magnitude improvement in the accuracy of 2-RDM calculations without an increase in their computational cost. The advance is based on a low-rank, dual formulation of an important constraint on the 2-RDM, the T 2 condition. Calculations are presented for metallic chains and a cadmium-selenide dimer. The low-scaling T 2 condition will have significant applications in atomic and molecular, condensed-matter, and nuclear physics.
DEFF Research Database (Denmark)
Vesborg, Peter Christian Kjærgaard; Seger, Brian
2016-01-01
Solar-drivenreduction of CO2 to solar fuels as an alternative to H2 via water splitting is an intriguing proposition. We modelthe solar-to-fuel (STF) efficiencies using realistic parameters basedon recently reported CO2 reduction catalysts with a highperformance tandem photoabsorber structure. CO...... and formate, whichare both two-electron reduction products, offer STF efficiencies (20.0%and 18.8%) competitively close to that of solar H2 (21.8%)despite markedly worse reduction catalysis. The slightly lower efficiencytoward carbon products is mainly due to electrolyte resistance, notoverpotential. Using...... a cell design where electrolyte resistance isminimized makes formate the preferred product from an efficiency standpoint(reaching 22.7% STF efficiency). On the other hand, going beyond a2 electron reduction reaction, the more highly reduced products seemunviable with presently available electrocatalysts...
Brics, M
2013-01-01
Favorably scaling numerical time-dependent many-electron techniques such as time-dependent density functional theory (TDDFT) with adiabatic exchange-correlation potentials typically fail in capturing highly correlated electron dynamics. We propose a method based on natural orbitals, i.e., the eigenfunctions of the one-body reduced density matrix, that is almost as inexpensive numerically as adiabatic TDDFT, but which is capable of describing correlated phenomena such as doubly excited states, autoionization, Fano profiles in the photoelectron spectra, and strong-field ionization in general. Equations of motion (EOM) for natural orbitals and their occupation numbers have been derived earlier. We show that by using renormalized natural orbitals (RNO) both can be combined into one equation governed by a hermitian effective Hamiltonian. We specialize on the two-electron spin-singlet system, known as being a "worst case" testing ground for TDDFT, and employ the widely used, numerically exactly solvable, one-dimens...
Yang, Yang; Dominguez, Adriel; Zhang, Du; Lutsker, Vitalij; Niehaus, Thomas A; Frauenheim, Thomas; Yang, Weitao
2017-03-28
The particle-particle random phase approximation (pp-RPA) is a promising method for studying charge transfer(CT) excitations. Through a detailed analysis on two-electron deficient systems, we show that the pp-RPA is always able to recover the long-distance asymptotic -1/R trend for CT excitations as a result of the concerted effect between orbital energies and the pp-RPA kernel. We also provide quantitative results for systems with relatively short donor-acceptor distances. With conventional hybrid or range-separated functionals, the pp-RPA performs much better than time-dependent density functional theory (TDDFT), although it still gives underestimated results which are not as good as TDDFT with system-dependent tuned functionals. For pp-RPA, there remain three great challenges in dealing with CT excitations. First, the delocalized frontier orbitals in strongly correlated systems often lead to difficulty with self-consistent field convergence as well as an incorrect picture with about half an electron transferred. Second, the commonly used density functionals often underestimate the energy gap between the highest occupied molecular orbital and the lowest unoccupied molecular orbital (LUMO) for the two-electron deficient species, resulting in systems with delocalized orbitals. Third, the performance of pp-RPA greatly depends on the energy difference between the LUMO and a higher virtual orbital. However, the meaning of the orbital energies for higher virtual orbitals is still not clear. We also discuss the performance of an approximate pp-RPA scheme that uses density functional tight binding (pp-DFTB) as reference and demonstrate that the aforementioned challenges can be overcome by adopting suitable range-separated hybrid functionals. The pp-RPA and pp-DFTB are thus promising general approaches for describing charge transfer excitations.
Directory of Open Access Journals (Sweden)
Jaime Castillo Pérez
2007-06-01
Full Text Available En 1991 M. Dotsenko presentó una generalización de la función hipergeométrica de Gauss denotada por 2Rτ1 (z, estableciendo además tanto su representación en serie como también su representación integral. Es importante notar que en 1999 Nina Virchenko y luego, en el 2003, Leda Galué consideraron esta función, introduciendo un conjunto de fórmulas de recurrencia y de diferenciación las cuales permiten simplificar algunos cálculos complicados. Kalla y colaboradores estudiaron esta función y presentaron una nueva forma unificada de la función Gamma, luego en el 2006, Castillo y colaboradores presentaron algunas representaciones simples para ésta función. En este trabajo se establecen algunas integrales impropias con límites de integración infinitos que involucran a la generalización τ de la función hipergeométrica de Gauss 2R1(a, b; c; τ ; z.In 1991 M. Dotsenko presented a generalization of Gauss’ hypergeometric function refered as 2Rτ1(z, and established its representation in series and integral. It is important to remark that in 1999 Nina Virchenko and, later in 2003, Leda Galu´e considered this function by introducing a set of recurrence and diﬀerentiation formulas; they permit simplify some complicated calculus. Kalla et al estudied this function and they presented a new uniﬁed form of the gamma function. Later in 2006, Castillo et al present some simple representation for this function. Along this paper work some improper integrals with integration inﬁnity limit involving generalized hypergeometric function2R1(a, b; c; τ ; z are displayed.
McCann, Scott D; Stahl, Shannon S
2015-06-16
involvement of two one-electron oxidants, either two Cu(II) species or Cu(II) and a nitroxyl cocatalyst. They show the ability of Cu to participate in traditional organometallic steps commonly associated with precious-metal catalysts, such as C-H activation and reductive elimination, but also demonstrate the accessibility of reaction steps not typically associated with precious-metal catalysts, such as single-electron transfer. Many of the Cu-catalyzed reactions offer advantages over analogous two-electron oxidation reactions mediated by palladium or other noble metals. For example, carbon-heteroatom oxidative coupling reactions in the first two reaction classes noted above are capable of using O2 as the terminal oxidant, while analogous reactions with Pd commonly require less desirable oxidants, such as hypervalent iodine or electrophilic halogen sources. In addition, the alcohol and amine oxidations in the third reaction class are significantly more efficient and show much broader scope and functional group tolerance than related Pd-catalyzed reactions. The mechanistic basis for these differences are described herein.
Sharp, P. M.; D'Amico, I.
2016-02-01
We consider a model system of two electrons confined in a two-dimensional harmonic oscillator potential, with the electrons interacting via an α / r2 potential, and subject to a magnetic field applied perpendicular to the plane of confinement. Our results show that variations in the strength of the electron-electron interaction generate a "band structure" in ground state metric spaces, which shares many characteristics with those generated as a result of varying the confinement potential. In particular, the metric spaces for wavefunctions, particle densities, and paramagnetic current densities all exhibit distinct "bands" and "gaps". The behavior of the polar angle of the bands also shares traits with that obtained by varying the confinement potential, but the behavior of the arc lengths of the bands on the metric space spheres can be seen to be different for the two cases and opposite for a large range of angular momentum values. The findings here and in Refs. [1,2] demonstrate that the "band structure" that arises in ground state metric spaces when a magnetic field is applied is a robust feature.
Trifonov, Alexander A; Borovkov, Ivan A; Fedorova, Elena A; Fukin, Georgii K; Larionova, Joulia; Druzhkov, Nikolai O; Cherkasov, Vladimir K
2007-01-01
Ytterbocene [Yb(C(5)MeH(4))(2)(thf)(2)] reacts with diazabutadiene 2,6-iPr(2)C(6)H(3)-N=CH-CH=N-C(6)H(3)iPr(2)-2,6 (DAD) as a one-electron reductant to afford a bis(cyclopentadienyl) Yb(III) derivative containing a DAD radical anion [Yb(C(5)MeH(4))(2)(dad(-.))]. However, ytterbocenes [YbCp*(2)(thf)(2)] (Cp*=C(5)Me(5), C(5)Me(4)H) coordinated by sterically demanding cyclopentadienyl ligands act as two-electron reductants in their reactions with DAD. These reactions occur by abstraction of one Cp* ring and result in the formation of novel Yb(III) mixed-ligand bent-sandwich complexes, [YbCp*(dad)(thf)], in which the dianion of DAD has an uncommon terminal eta(4)-coordination to the ytterbium atom. The variable-temperature magnetic measurements of complex [Yb(C(5)Me(5))(dad)(thf)] suggest the existence of redox tautomerism for this compound.
Energy Technology Data Exchange (ETDEWEB)
Reuschl, Regina
2008-07-01
Experiments on the 1s Lamb-shift in heavy H-like ions and on the intra-shell transitions in heavy He-like systems have been performed. These investigations are of particular interest to verify the validity of quantum electrodynamics (QED) in extremely strong Coulomb fields. In addition, in heavy systems not only QED but also relativistic effects start to play a key role. The experiments have been performed at the gas-jet target of the experimental storage ring (ESR) at GSI. In an experiment with He-like uranium we were able to directly measure the intra-shell transition 2{sup 3}P{sub 2}{yields}2{sup 3}S{sub 1}, in a high-Z system for the very first time. This has been achieved by combining the results from a high-resolution Bragg crystal-spectrometer and a standard planar Germanium detector. A fit of the experimental spectrum with data obtained from a simulation shows, the theoretical predictions describe the transition dynamics very well in this two-electron system. Another experiment has been performed on H-like lead to investigate the 1s Lamb-shift in heavy H-like systems. Here, a high-resolution Laue crystal-spectrometer has been commissioned together with novel high-resolution two dimensional micro-strip Ge-detectors. The combination of both instruments is a very promising tool for future high-precision X-ray experiments. (orig.)
Between Involvement and Detachment
DEFF Research Database (Denmark)
Thomasen, Gry
a traditional reading of de Gaulle’s policies, and feared that if Gaullist thinking spread among the European allies, it would merit to a return to traditional European power politics. The analysis shows that, by 1964 the administration believed, according to this study, that NATO’s principle of integration......Between Involvement and Detachment takes grasp with the Johnson administration’s (1963-1969) perceptions of and responses to the Western European realignments. Arguing that the Johnson administration set out to maintain the American unilateralist position in the transatlantic relation, not just......, essentially, were detached as America rejected the European reason of state. The Western European realignments were recorded in the Johnson administration with de Gaulle’s critique of US hegemony in Western Europe in the early 1960s. The thesis argues that the administration to a large extent had...
Taras K. Antal; Sarvikas, Päivi; Tyystjärvi, Esa
2009-01-01
The oxygen-evolving complex of Photosystem II cycles through five oxidation states (S0–S4), and dark incubation leads to 25% S0 and 75% S1. This distribution cannot be reached with charge recombination reactions between the higher S states and the electron acceptor QB−. We measured flash-induced oxygen evolution to understand how S3 and S2 are converted to lower S states when the electron required to reduce the manganese cluster does not come from QB−. Thylakoid samples preconditioned to make...
Parental Involvement in Special Education Curriculum
Westwood-Robinette, Nicole M.
2014-01-01
Educators and researchers have long considered parental involvement an integral part in the success of students and researchers have concluded that there is a connection between parental involvement and the retention rates of students who are involved in regular education curriculum. However, much less information is available regarding the…
Directory of Open Access Journals (Sweden)
Hemmen Bena
2009-01-01
Full Text Available Abstract Background In conventional multi-trauma care service (CTCS, patients are admitted to hospital via the accident & emergency room. After surgery they are transferred to the IC-unit followed by the general surgery ward. Ensuing treatment takes place in a hospital's outpatient clinic, a rehabilitation centre, a nursing home or the community. Typically, each of the CTCS partners may have its own more or less autonomous treatment perspective. Clinical evidence, however, suggests that an integrated multi-trauma rehabilitation approach ('Supported Fast-track multi-Trauma Rehabilitation Service': SFTRS, featuring: 1 earlier transfer to a specialised trauma rehabilitation unit; 2 earlier start of 'non-weight-bearing' training and multidisciplinary treatment; 3 well-documented treatment protocols; 4 early individual goal-setting; 5 co-ordination of treatment between trauma surgeon and physiatrist, and 6 shorter lengths-of-stay, may be more (cost-effective. This paper describes the design of a prospective cohort study evaluating the (cost- effectiveness of SFTRS relative to CTCS. Methods/design The study population includes multi-trauma patients, admitted to one of the participating hospitals, with an Injury Severity Scale score > = 16, complex multiple injuries in several extremities or complex pelvic and/or acetabulum fractures. In a prospective cohort study CTCS and SFTRS will be contrasted. The inclusion period is 19 months. The duration of follow-up is 12 months, with measurements taken at baseline, and at 3,6,9 and 12 months post-injury. Primary outcome measures are 'quality of life' (SF-36 and 'functional health status' (Functional Independence Measure. Secondary outcome measures are the Hospital Anxiety & Depression Scale, the Mini-Mental State Examination as an indicator of cognitive functioning, and the Canadian Occupational Performance Measure measuring the extent to which individual ADL treatment goals are met. Costs will be assessed
Florens, Serge; Freyn, Axel; Roch, Nicolas; Wernsdorfer, Wolfgang; Balestro, Franck; Roura-Bas, Pablo; Aligia, A A
2011-06-22
We review here some universal aspects of the physics of two-electron molecular transistors in the absence of strong spin-orbit effects. Several recent quantum dot experiments have shown that an electrostatic backgate could be used to control the energy dispersion of magnetic levels. We discuss how the generally asymmetric coupling of the metallic contacts to two different molecular orbitals can indeed lead to a gate-tunable Hund's rule in the presence of singlet and triplet states in the quantum dot. For gate voltages such that the singlet constitutes the (non-magnetic) ground state, one generally observes a suppression of low voltage transport, which can yet be restored in the form of enhanced cotunneling features at finite bias. More interestingly, when the gate voltage is controlled to obtain the triplet configuration, spin S = 1 Kondo anomalies appear at zero bias, with non-Fermi liquid features related to the underscreening of a spin larger than 1/2. Finally, the small bare singlet-triplet splitting in our device allows fine-tuning with the gate between these two magnetic configurations, leading to an unscreening quantum phase transition. This transition occurs between the non-magnetic singlet phase, where a two-stage Kondo effect occurs, and the triplet phase, where the partially compensated (underscreened) moment is akin to a magnetically 'ordered' state. These observations are put theoretically into a consistent global picture by using new numerical renormalization group simulations, tailored to capture sharp finite-voltage cotunneling features within the Coulomb diamonds, together with complementary out-of-equilibrium diagrammatic calculations on the two-orbital Anderson model. This work should shed further light on the complicated puzzle still raised by multi-orbital extensions of the classic Kondo problem.
Mazziotti, David A
2007-05-14
Two-electron reduced density matrices (2-RDMs) have recently been directly determined from the solution of the anti-Hermitian contracted Schrodinger equation (ACSE) to obtain 95%-100% of the ground-state correlation energy of atoms and molecules, which significantly improves upon the accuracy of the contracted Schrodinger equation (CSE) [D. A. Mazziotti, Phys. Rev. Lett. 97, 143002 (2006)]. Two subsets of the CSE, the ACSE and the contraction of the CSE onto the one-particle space, known as the 1,3-CSE, have two important properties: (i) dependence upon only the 3-RDM and (ii) inclusion of all second-order terms when the 3-RDM is reconstructed as only a first-order functional of the 2-RDM. The error in the 1,3-CSE has an important role as a stopping criterion in solving the ACSE for the 2-RDM. Using a computationally more efficient implementation of the ACSE, the author treats a variety of molecules, including H2O, NH3, HCN, and HO3-, in larger basis sets such as correlation-consistent polarized double- and triple-zeta. The ground-state energy of neon is also calculated in a polarized quadruple-zeta basis set with extrapolation to the complete basis-set limit, and the equilibrium bond length and harmonic frequency of N2 are computed with comparison to experimental values. The author observes that increasing the basis set enhances the ability of the ACSE to capture correlation effects in ground-state energies and properties. In the triple-zeta basis set, for example, the ACSE yields energies and properties that are closer in accuracy to coupled cluster with single, double, and triple excitations than to coupled cluster with single and double excitations. In all basis sets, the computed 2-RDMs very closely satisfy known N-representability conditions.
Pandey, Chandan
2015-01-01
This book is intended for developers who are either already involved with enterprise integration or planning to venture into the domain. Basic knowledge of Java and Spring is expected. For newer users, this book can be used to understand an integration scenario, what the challenges are, and how Spring Integration can be used to solve it. Prior experience of Spring Integration is not expected as this book will walk you through all the code examples.
Directory of Open Access Journals (Sweden)
MA. Ilir Bejta
2013-12-01
Economic integration induces immigrants to increase contacts and be part of economic networks and social networks too, as well as improve, as a necessity deriving from the economic competition, their human capital capacities and capabilities getting use of international labour market. Considering economic and human capital development we will measure their impact on the social welfare and integration of the ethnic immigrant minority groups in the modern society (Albanians in Province of Milan, Italy.
Hernandez, Penni; Podchiyska, Tanya; Weber, Susan; Ferris, Todd; Lowe, Henry
2009-11-14
The Stanford Translational Research Integrated Database Environment (STRIDE) clinical data warehouse integrates medication information from two Stanford hospitals that use different drug representation systems. To merge this pharmacy data into a single, standards-based model supporting research we developed an algorithm to map HL7 pharmacy orders to RxNorm concepts. A formal evaluation of this algorithm on 1.5 million pharmacy orders showed that the system could accurately assign pharmacy orders in over 96% of cases. This paper describes the algorithm and discusses some of the causes of failures in mapping to RxNorm.
Energy Technology Data Exchange (ETDEWEB)
Bouri, C
2007-04-15
This work presents a study of the {sup 1}P{sup 0} excited states of He that can be reached by absorption of a single photon carrying an energy close to the double ionization threshold (DIT) (79 eV). Above the DIT, these states are the double continuum states; below, they are the double excited states. These two types of states are tightly coupled to the single continuum states with or without excitation of the residual ion He{sup +}, owing to their degeneracy in energy. In a one-photon process, these states can only be formed owing to the electronic correlations in the system which must be well described to obtain quantitative good results. Our study is a part of the work which aims at a united description of all these doubly excited, ionized-excited, and double continuum states. We use the Hyperspherical R-Matrix with Semiclassical Outgoing Waves (HRM-SOW) method, initially dedicated to double photoionization studies. We extend it to extract information on the single continuum. This extension allows us to compute cross sections of single photoionization with or without excitation up to n 50 for an excess of 100 meV just above the double ionization threshold. A deep insight into this process is given by a partial waves analysis. The results obtained shed light on the key role of angular and radial correlations. The numerous data we obtain on double and single ionization allow us to establish a continuity relation between these two processes. We show that single ionization with an infinite excitation of the residual ion merges into double photoionization when the excess energy is redistributed between the two electrons. It appears that this relation is valid not only for low but also for high photon energies. Since the HRM-SOW can produce the integrated cross section for double photoionization with high accuracy in the low energy domain, we check the Wannier threshold law. The parameters extracted support strongly this threshold law, and are in good agreement with
... Privacy Policy Sitemap Learn Engage Donate About TSC Eyes Campbell (1905) first described the eye involvement in ... some form of eye involvement. Nonretinal and Retinal Eye Findings Facial angiofibromas may involve the eyelids of ...
Who and What Does Involvement Involve?
DEFF Research Database (Denmark)
Hansen, Jeppe Oute; Petersen, Anders; Huniche, Lotte
2015-01-01
elucidates how a psycho-ideological discourse positions the mentally ill person as weak, incapable, and ineffective. By contrast, the supporting relative is positioned as a strong, capable, and effective co-therapist. Furthermore, the analysis considers how this dominant discourse of involvement...... theoretical perspective laid out by Ernesto Laclau and Chantal Mouffe, the aim of this study is to show how the dominant discourse about involvement at the political and clinical sites is constituted by understandings of mentally ill individuals and by political objectives of involvement. The analysis...... the responsibility toward the mental health of the ill individual as well as toward the psychological milieu of the family....
Haiyu Xu; Yanqiong Zhang; Yun Lei; Xiumei Gao; Huaqiang Zhai; Na Lin; Shihuan Tang; Rixin Liang; Yan Ma; Defeng Li; Yi Zhang; Guangrong Zhu; Hongjun Yang; Luqi Huang
2014-01-01
Traditional Chinese medicine (TCM) is one of the oldest East Asian medical systems. The present study adopted a systems biology-based approach to provide new insights relating to the active constituents and molecular mechanisms underlying the effects of dragon's blood (DB) tablets for the treatment of colitis. This study integrated chemical analysis, prediction of absorption, distribution, metabolism, and excretion (ADME), and network pharmacology. Firstly, a rapid, reliable, and accurate ult...
HETEROGENEOUS INTEGRATION TECHNOLOGY
2017-08-24
in- package integration. It involves the integration of circuits from fully processed wafers using micro- bumps and TSVs. There are 3 basic kinds of... bumping ” and “Cu-to-Cu” categories. The first approach involves the fabrication of micro- bumps on both sides of the thinned wafers with TSVs, and...interfacing wafers with bumps aligned. The application of pressure and heat makes permanent contact between bumps . A thin adhesive layer can be used between
Integrity in Transactional Leadership
Miller, Thomas
2011-01-01
This chapter begins with a discussion of the impact of limited resources on the integrity of transactions between students and student affairs administrators. A framework and guiding principles for maintaining integrity are offered, and then some general principles for transactions with students are presented. Next, the chapter involves integrity…
Four Ways to Skin a Definite Integral
Dence, Thomas; Dence, Joseph
2010-01-01
The integral of 1/(1 + x[superscript 2]) is standard in elementary calculus, but the related integral 1/(1 + x[superscript 4]) rarely appears. In this article we examine the latter integral, computing its value by four different methods; several that involve standard elementary calculus techniques, and several involving complex integration.
Axiomatic Characterizations of the Choquet Integral
DEFF Research Database (Denmark)
Groes, Ebbe; Whitta-Jacobsen, Hans Jørgen; Sloth, Birgitte
The Choquet integral is an integral part of recent advances in decision theory involving non-additive measures. In this article we present two new axiomatic characterizations of this functional......The Choquet integral is an integral part of recent advances in decision theory involving non-additive measures. In this article we present two new axiomatic characterizations of this functional...
Axiomatic Characterizations of the Choquet Integral
DEFF Research Database (Denmark)
Groes, Ebbe; Jacobsen, Hans Jørgen; Sloth, Birgitte
1998-01-01
The Choquet integral is an integral part of recent advances in decision theory involving non-additive measures. In this article we present two new axiomatic characterizations of this functional.......The Choquet integral is an integral part of recent advances in decision theory involving non-additive measures. In this article we present two new axiomatic characterizations of this functional....
Four Ways to Skin a Definite Integral
Dence, Thomas; Dence, Joseph
2010-01-01
The integral of 1/(1 + x[superscript 2]) is standard in elementary calculus, but the related integral 1/(1 + x[superscript 4]) rarely appears. In this article we examine the latter integral, computing its value by four different methods; several that involve standard elementary calculus techniques, and several involving complex integration.
Are free radicals involved in thiol-based redox signaling?
Winterbourn, Christine C
2015-03-01
Cells respond to many stimuli by transmitting signals through redox-regulated pathways. It is generally accepted that in many instances signal transduction is via reversible oxidation of thiol proteins, although there is uncertainty about the specific redox transformations involved. The prevailing view is that thiol oxidation occurs by a two electron mechanism, most commonly involving hydrogen peroxide. Free radicals, on the other hand, are considered as damaging species and not generally regarded as important in cell signaling. This paper examines whether it is justified to dismiss radicals or whether they could have a signaling role. Although there is no direct evidence that radicals are involved in transmitting thiol-based redox signals, evidence is presented that they are generated in cells when these signaling pathways are activated. Radicals produce the same thiol oxidation products as two electron oxidants, although by a different mechanism, and at this point radical-mediated pathways should not be dismissed. There are unresolved issues about how radical mechanisms could achieve sufficient selectivity, but this could be possible through colocalization of radical-generating and signal-transducing proteins. Colocalization is also likely to be important for nonradical signaling mechanisms and identification of such associations should be a priority for advancing the field.
Libcint: An efficient general integral library for Gaussian basis functions
Sun, Qiming
2014-01-01
An efficient integral library Libcint was designed to automatically implement general integrals for Gaussian-type scalar and spinor basis functions. The library can handle arbitrary integral expressions on top of $\\mathbf{p}$, $\\mathbf{r}$ and $\\sigma$ operators with one-electron overlap and nuclear attraction, two-electron Coulomb and Gaunt operators. Using a symbolic algebra tool, new integrals are derived and translated to C code programmatically. The generated integrals can be used in various types of molecular properties. In the present work, we computed the analytical gradients and NMR shielding constants at both non-relativistic and four-component relativistic Hartree-Fock level to demonstrate the capability of the integral library. Due to the use of kinetically balanced basis and gauge including atomic orbitals, the relativistic analytical gradients and shielding constants requires the integral library to handle the fifth-order electron repulsion integral derivatives. The generality of the integral li...
... Privacy Policy Sitemap Learn Engage Donate About TSC Lungs Lung involvement in tuberous sclerosis complex (TSC) has ... testing. (Krueger et al., 2013) What Are the Lung Features of TSC? Two forms of lung involvement ...
Energy Technology Data Exchange (ETDEWEB)
Bordenave-Montesquieu, A.; Benoit-Cattin, P.; Gleizes, A.; Marrakchi, A.I.; Dousson, S.; Hitz, D.
1985-07-01
Singly differential cross sections for two-electron capture into autoionising states (nl,n'l') with n=2,3,4 and n'>=n in Nsup(q+) (q=6,7) on He and H/sub 2/ collisions have been measured at 10,5q ke V collision energy and an observation angle thetasub(lab)=11.6/sup 0/. Total cross sections are estimated assuming isotropic angular distributions. (orig.).
Martínez, Luary C; Yakhnin, Helen; Camacho, Martha I; Georgellis, Dimitris; Babitzke, Paul; Puente, José L; Bustamante, Víctor H
2011-06-01
Salmonella pathogenicity islands 1 and 2 (SPI-1 and SPI-2) play key roles in the pathogenesis of Salmonella enterica. Previously, we showed that when Salmonella grows in Luria-Bertani medium, HilD, encoded in SPI-1, first induces the expression of hilA, located in SPI-1, and subsequently of the ssrAB operon, located in SPI-2. These genes code for HilA and the SsrA/B two-component system, the positive regulators of the SPI-1 and SPI-2 regulons respectively. In this study, we demonstrate that CsrA, a global regulatory RNA binding protein, post-transcriptionally regulates hilD expression by directly binding near the Shine-Dalgarno and translation initiation codon sequences of the hilD mRNA, preventing its translation and leading to its accelerated turnover. Negative regulation is counteracted by the global SirA/BarA two-component system, which directly activates the expression of CsrB and CsrC, two non-coding regulatory RNAs that sequester CsrA, thereby preventing it from binding to its target mRNAs. Our results illustrate the integration of global and specific regulators into a multifactorial regulatory cascade controlling the expression of virulence genes acquired by horizontal transfer events.
Xu, Haiyu; Zhang, Yanqiong; Lei, Yun; Gao, Xiumei; Zhai, Huaqiang; Lin, Na; Tang, Shihuan; Liang, Rixin; Ma, Yan; Li, Defeng; Zhang, Yi; Zhu, Guangrong; Yang, Hongjun; Huang, Luqi
2014-01-01
Traditional Chinese medicine (TCM) is one of the oldest East Asian medical systems. The present study adopted a systems biology-based approach to provide new insights relating to the active constituents and molecular mechanisms underlying the effects of dragon's blood (DB) tablets for the treatment of colitis. This study integrated chemical analysis, prediction of absorption, distribution, metabolism, and excretion (ADME), and network pharmacology. Firstly, a rapid, reliable, and accurate ultra-performance liquid chromatography-electrospray ionization-tandem mass spectrometry method was employed to identify 48 components of DB tablets. In silico prediction of the passive absorption of these compounds, based on Caco-2 cell permeability, and their P450 metabolism enabled the identification of 22 potentially absorbed components and 8 metabolites. Finally, networks were constructed to analyze interactions between these DB components/metabolites absorbed and their putative targets, and between the putative DB targets and known therapeutic targets for colitis. This study provided a great opportunity to deepen the understanding of the complex pharmacological mechanisms underlying the effects of DB in colitis treatment.
Directory of Open Access Journals (Sweden)
Haiyu Xu
Full Text Available Traditional Chinese medicine (TCM is one of the oldest East Asian medical systems. The present study adopted a systems biology-based approach to provide new insights relating to the active constituents and molecular mechanisms underlying the effects of dragon's blood (DB tablets for the treatment of colitis. This study integrated chemical analysis, prediction of absorption, distribution, metabolism, and excretion (ADME, and network pharmacology. Firstly, a rapid, reliable, and accurate ultra-performance liquid chromatography-electrospray ionization-tandem mass spectrometry method was employed to identify 48 components of DB tablets. In silico prediction of the passive absorption of these compounds, based on Caco-2 cell permeability, and their P450 metabolism enabled the identification of 22 potentially absorbed components and 8 metabolites. Finally, networks were constructed to analyze interactions between these DB components/metabolites absorbed and their putative targets, and between the putative DB targets and known therapeutic targets for colitis. This study provided a great opportunity to deepen the understanding of the complex pharmacological mechanisms underlying the effects of DB in colitis treatment.
Indian Academy of Sciences (India)
Mridula Garg; Shweta Mittal
2004-05-01
In the present paper we derive a unified new integral whose integrand contains products of Fox -function and a general class of polynomials having general arguments. A large number of integrals involving various simpler functions follow as special cases of this integral.
CSIR Research Space (South Africa)
Ackermann, ER
2012-09-01
Full Text Available We use Cavalieri’s principle to develop a novel integration technique which we call Cavalieri integration. Cavalieri integrals differ from Riemann integrals in that non-rectangular integration strips are used. In this way we can use single Cavalieri...
Institute of Scientific and Technical Information of China (English)
薛花
2016-01-01
当前由于对情感融入品德培养的重要性，紧迫性认识不足，致使品德培养缺乏实效性，社会出现道德滑坡。品德培养不是简单的道德知识的灌输与说教，还必须激发道德接受主体的情感需要，才能有效避免教而不化。通过培育美感、移情(同理心)、羞耻感等情感融入品德培养的途径，提高品德培养的实效性。%The importance and urgency of understanding of sentiment involvement moral cultivation is not enough, so the moral training is lack of actual effect and the social moral landslide. Moral cultivation is not a simple moral knowledge and the sermon, it also should stimulate main body accept the moral emotional need, it can effectively a-void teach without consequences. We can improve the actual effect of moral cultivation by the way of cultivating aesthetic feeling, empathy (empathy) and shame which can make emotion into moral cultivation.
Calculus Technique of Integration by Parts, Correlated with a Geometric Picture
Fromhold, Albert T., Jr.
2005-01-01
The method of integration by parts is one of the most useful in integral calculus. Among the most important applications is the integration of differentials involving products, differentials in involving logarithms, and differentials involving inverse circular functions.
Benchmark values for molecular three-center integrals arising in the Dirac equation
Bagci, A.; Hoggan, P. E.
2015-01-01
The authors in their previous papers obtained compact, arbitrarily accurate expressions for two-center one- and two-electron relativistic molecular integrals expressed over Slater-type orbitals. In this present study, the accuracy limits of given expressions is examined for three-center nuclear attraction integrals, which are the first integral set do not have analytically closed form relations. They are expressed through new molecular auxiliary functions obtained via Neumann expansion of Cou...
Bugdol, Marek
2015-01-01
Examining the challenges of integrated management, this book explores the importance and potential benefits of using an integrated approach as a cross-functional concept of management. It covers not only standardized management systems (e.g. International Organization for Standardization), but also models of self-assessment, as well as different types of integration. Furthermore, it demonstrates how processes and systems can be integrated, and how management efficiency can be increased. The major part of this book focuses on management concepts which use integration as a key tool of management processes (e.g. the systematic approach, supply chain management, virtual and network organizations, processes management and total quality management). Case studies, illustrations, and tables are also provided to exemplify and illuminate the content, as well as examples of successful and failed integrations. Providing a particularly useful resource to managers and specialists involved in the improvement of organization...
Directory of Open Access Journals (Sweden)
Junesang Choi
2014-01-01
Full Text Available A remarkably large number of integral transforms and fractional integral formulas involving various special functions have been investigated by many authors. Very recently, Agarwal gave some integral transforms and fractional integral formulas involving the Fp(α,β(·. In this sequel, using the same technique, we establish certain integral transforms and fractional integral formulas for the generalized Gauss hypergeometric functions Fp(α,β,m(·. Some interesting special cases of our main results are also considered.
Doctors' involvement in torture
DEFF Research Database (Denmark)
Sonntag, Jesper
2008-01-01
Doctors from both non-democratic and democratic countries are involved in torture. The majority of doctors involved in torture are doctors at risk. Doctors at risk might compromise their ethical duty towards patients for the following possible reasons: individual factors (such as career, economic...
Smith, Johanna A; Wang, Feng-Xiang; Zhang, Hui; Wu, Kou-Juey; Williams, Kevin Jon; Daniel, René
2008-01-22
Retroviral transduction involves integrase-dependent linkage of viral and host DNA that leaves an intermediate that requires post-integration repair (PIR). We and others proposed that PIR hijacks the host cell double-strand DNA break (DSB) repair pathways. Nevertheless, the geometry of retroviral DNA integration differs considerably from that of DSB repair and so the precise role of host-cell mechanisms in PIR remains unclear. In the current study, we found that the Nijmegen breakage syndrome 1 protein (NBS1), an early sensor of DSBs, associates with HIV-1 DNA, recruits the ataxia telangiectasia-mutated (ATM) kinase, promotes stable retroviral transduction, mediates efficient integration of viral DNA and blocks integrase-dependent apoptosis that can arise from unrepaired viral-host DNA linkages. Moreover, we demonstrate that the ATM kinase, recruited by NBS1, is itself required for efficient retroviral transduction. Surprisingly, recruitment of the ATR kinase, which in the context of DSB requires both NBS1 and ATM, proceeds independently of these two proteins. A model is proposed emphasizing similarities and differences between PIR and DSB repair. Differences between the pathways may eventually allow strategies to block PIR while still allowing DSB repair.
Integral trees and integral graphs
Wang, Ligong
2005-01-01
This monograph deals with integral graphs, Laplacian integral regular graphs, cospectral graphs and cospectral integral graphs. The organization of this work, which consists of eight chapters, is as follows.
Consumer Involvement in Rehabilitation
Daniels, Susan
1976-01-01
With the emphasis on consumer involvement in the Rehabilitation Act of 1973, changes in the counseling relationship must occur. This article discusses new interaction patterns for consumer and counselor. (Author)
Clinical studies involving probiotics
Degnan, Fred H
2012-01-01
Researchers from a diverse array of scientific disciplines have focused and continue to focus on opportunities and areas for responsible clinical research involving the possible beneficial health effects of “probiotics.” Investigators and researchers should be aware that not all clinical research involving probiotics reasonably falls within the requirements of the “investigational new drug” (IND) rubric administered and enforced by the US Food and Drug Administration. In determining whether a...
Verkuyten, Maykel
2016-01-01
The integration paradox refers to the phenomenon of the more highly educated and structurally integrated immigrants turning away from the host society, rather than becoming more oriented toward it. This article provides an overview of the empirical evidence documenting this paradox in the Netherlands. In addition, the theoretical arguments and the available findings about the social psychological processes involved in this paradox are considered. The existing evidence for the integration paradox and what might explain it form the basis for making suggestion for future theoretical work and empirical research, and for discussing possible policy implications. PMID:27152028
Pancreatic Involvement in Melioidosis
Directory of Open Access Journals (Sweden)
Vui Heng Chong
2010-07-01
Full Text Available Context Melioidosis is endemic to tropical regions and, despite the common occurrence of intra-abdominal abscesses, pancreatic involvement in melioidosis has not previously been reported. Objective We report our experience with pancreatic melioidosis. Patients All 65 patients treated for melioidosis who had computed tomography (CT scans were identified from prospective databases and were retrospectively reviewed. Main outcome measures A detailed review of cases with pancreas involvement was carried out. Results There were four cases (three males and one female; median age 29.5 years, range: 25-48 years with pancreatic melioidosis, giving a prevalence of 6.2%. All had predisposing conditions (two had poorly controlled diabetes mellitus and two had thalassemia for melioidosis. Fever (100%, anorexia (100%, weight loss (100%, rigor (75% and abdominal pain (75% were the most common symptoms at presentation and the median duration of symptoms before presentation was six weeks (range: 2-8 weeks. All pancreatic abscesses were detected on CT scan. Multiple foci involvement was common (3 to 6 sites: blood (4 patients, liver (3 patients, psoas muscle (2 patients, spleen (2 patients, infected ascites (2 patients and lung (1 patient. Pancreatic involvement ranged from multi-focal micro-abscesses to focal large abscesses and involved all parts of the pancreas (body 100%, head 75% and tail 50%. Associated pancreatic findings included splenic vein thrombosis, peripancreatic inflammation and peripancreatic fat streaking. All the pancreatic abscesses were resolved with antibiotics without requiring pancreatic abscess drainage (including one patient who died from disseminated melioidosis. Conclusion Pancreatic involvement typically occurs as part of multi-organ involvement and commonly manifests as multifoci micro-abscesses. Associated pancreatic abnormalities were also common. All responded to treatment without requiring drainage
Directory of Open Access Journals (Sweden)
Tom Atlee
2010-03-01
Full Text Available Using the definition proposed here, integral politics can be a process of integrating diverse perspectives into wholesome guidance for a community or society. Characteristics that follow from this definition have ramifications for understanding what such political processes involve. Politics becomes integral as it transcends partisan battle and nurtures generative conversation toward the common good. Problems, conflicts and crises become opportunities for new (or renewed social coherence. Conversational methodologies abound that can help citizen awareness temporarily expand during policy-making, thus helping raise society’s manifested developmental stage. Convening archetypal stakeholders or randomly selected citizens in conversations designed to engage the broader public enhances democratic legitimacy. With minimal issue- and candidate-advocacy, integral political leaders would develop society’s capacity to use integral conversational tools to improve its health, resilience, and collective intelligence. This both furthers and manifests evolution becoming conscious of itself.
[Pulmonary involvements of sarcoidosis].
Ohmichi, M; Hiraga, Y; Hirasawa, M
1990-01-01
We reported about intrathoracic changes and prognosis of 686 patients with sarcoidosis diagnosed in our hospital between 1963 and 1988. We evaluated CT findings in 135 patients with sarcoidosis and found pulmonary involvements in 81. We analyzed CT findings according to the classification by Tuengerthal which classified radiographic findings combining ILO classification of pneumoconiosis and characteristic findings of bronchovascular sheath with sarcoidosis. The CT findings were as follows: small opacities (44 out of 81 cases, 54.3%), large opacities (37 cases, 46.7%). Additional findings were as follows: peribronchial marking (42 cases, 51.9%), contraction (17 cases, 21.0%), pleural involvement (9 cases, 11.1%), bulla (5 cases, 6.2%). The characteristic CT findings of serious sarcoidosis were extasis of bronchus, thickening of the bronchial wall, unclearness of vascular shadow, atelectasis and thickening of pleura. Concerning the prognosis of pulmonary involvement, according to age, patients younger than 30 years old at initial diagnosis were better than those of 30 years and over in terms of disappearance of pulmonary involvements. According to stage, patients of stage I and stage II were better than those of stage III. Among the patients we were able to observe chest X-ray findings during five years according to the character of shadow, ill-defined shadow of small opacities and rounded shadows of large opacities had a higher disappearance rate of pulmonary involvements than irregular shadows of large opacities, atelectasis and contraction.
Musculoskeletal involvement in sarcoidosis*, **
Nessrine, Akasbi; Zahra, Abourazzak Fatima; Taoufik, Harzy
2014-01-01
Sarcoidosis is a multisystem inflammatory disorder of unknown cause. It most commonly affects the pulmonary system but can also affect the musculoskeletal system, albeit less frequently. In patients with sarcoidosis, rheumatic involvement is polymorphic. It can be the presenting symptom of the disease or can appear during its progression. Articular involvement is dominated by nonspecific arthralgia, polyarthritis, and Löfgren's syndrome, which is defined as the presence of lung adenopathy, arthralgia (or arthritis), and erythema nodosum. Skeletal manifestations, especially dactylitis, appear mainly as complications of chronic, multiorgan sarcoidosis. Muscle involvement in sarcoidosis is rare and usually asymptomatic. The diagnosis of rheumatic sarcoidosis is based on X-ray findings and magnetic resonance imaging findings, although the definitive diagnosis is made by anatomopathological study of biopsy samples. Musculoskeletal involvement in sarcoidosis is generally relieved with nonsteroidal anti-inflammatory drugs or corticosteroids. In corticosteroid-resistant or -dependent forms of the disease, immunosuppressive therapy, such as treatment with methotrexate or anti-TNF-α, is employed. The aim of this review was to present an overview of the various types of osteoarticular and muscle involvement in sarcoidosis, focusing on their diagnosis and management. PMID:24831403
Musculoskeletal involvement in sarcoidosis
Directory of Open Access Journals (Sweden)
Akasbi Nessrine
2014-04-01
Full Text Available Sarcoidosis is a multisystem inflammatory disorder of unknown cause. It most commonly affects the pulmonary system but can also affect the musculoskeletal system, albeit less frequently. In patients with sarcoidosis, rheumatic involvement is polymorphic. It can be the presenting symptom of the disease or can appear during its progression. Articular involvement is dominated by nonspecific arthralgia, polyarthritis, and Löfgren's syndrome, which is defined as the presence of lung adenopathy, arthralgia (or arthritis, and erythema nodosum. Skeletal manifestations, especially dactylitis, appear mainly as complications of chronic, multiorgan sarcoidosis. Muscle involvement in sarcoidosis is rare and usually asymptomatic. The diagnosis of rheumatic sarcoidosis is based on X-ray findings and magnetic resonance imaging findings, although the definitive diagnosis is made by anatomopathological study of biopsy samples. Musculoskeletal involvement in sarcoidosis is generally relieved with nonsteroidal anti-inflammatory drugs or corticosteroids. In corticosteroid-resistant or -dependent forms of the disease, immunosuppressive therapy, such as treatment with methotrexate or anti-TNF-α, is employed. The aim of this review was to present an overview of the various types of osteoarticular and muscle involvement in sarcoidosis, focusing on their diagnosis and management.
Variables Affecting Two Electron Transport System Assays
Burton, G. Allen; Lanza, Guy R.
1986-01-01
Several methodological variables were critical in two commonly used electron transport activity assays. The dehydrogenase assay based on triphenyl formazan production exhibited a nonlinear relationship between formazan production (dehydrogenase activity) and sediment dilution, and linear formazan production occurred for 1 h in sediment slurries. Activity decreased with increased time of sediment storage at 4°C. Extraction efficiencies of formazan from sediment varied with alcohol type; methan...
Involve physicians in marketing.
Randolph, G T; Baker, K M; Laubach, C A
1984-01-01
Many everyday problems in medical group practice can be attacked by a marketing approach. To be successful, however, this kind of approach must have the full support of those involved, especially the physicians, since they are the principal providers of healthcare services. When marketing is presented in a broad context, including elements such as patient mix, population distribution, and research, physicians are more likely to be interested and supportive. The members of Geisinger Medical Center's Department of Cardiovascular Medicine addressed their patient appointment backlog problem with a marketing approach. Their method is chronicled here and serves as a fine example of how physician involvement in marketing can lead to a positive outcome.
A unified approach to several results involving integrals of multifunctions
Balder, E.J.
2001-01-01
A well-known equivalence of randomization result of Wald and Wolfowitz states that any Young measure can be regarded as a probability measure on the set of all measurable functions. Here we give a sucient condition for the Young measure to be equivalent to a probability measure on the set of all int
Reaching Parents Through Involvement
Schmerber, Ronald J.
1974-01-01
The parent involvement program evolved from the needs of parents. Basic to the program is the concept of parenting, which implies taking positive action to facilitate and meet the needs of the children ahe family. Parents participate in the development, implementation, and evaluation of their child's program. (Author)
Renewable energy integration challenges and solutions
Hossain, Jahangir
2014-01-01
This book examines challenges involved in the integration of renewable energy into existing electricity grids. It provides models of power systems to show how the integration will effect conventional grids and various solutions to minimize the impacts.
Network integration; Network integration
Energy Technology Data Exchange (ETDEWEB)
NONE
2000-02-29
Together with the rapid spread of information network, a shift is seen from the conventional original network to the system based on the standard network also in the monitoring/control field. In the network construction in the monitoring/control field, Meidensha uses internet/intranet technology and multimedia technology and is working on the construction of multimedia network into which sound/image/data are integrated. The paper indicates an example of constructing a large-scale network based on the ATM network constructed by the company and an example of constructing a network based on the Ethernet. The image system is coded/decoded by MPEG2 encoder/decoder and delivered by ATM switch. The sound system is connected to ATM network via CLAD and constructs PBX net. The data system which intercommunicates among terminals interconnects routers on ATM network using TCP/IP. Further, it copes with difficulties such as cable cut by making a detour for the ATM network. (translated by NEDO)
Reflections on 'autistic integrity'.
Russell, Barbara
2012-03-01
Autism, particularly its moderate to severe forms, has prompted considerable scientific study and clinical involvement because the associated behaviours imply disconnections with valued features of a 'good' life, such as close relationships, enjoyment, and adaptability. Proposed causes of autism involve potent philosophical concepts including consciousness, identity, mind, and relationality. The concept of autistic integrity is used by Barnbaum in The Ethics of Autism: Among Them, But Not of Them to help provide moral justification to stop efforts to cure adults with autism, especially if the cause is presumed to be a lack of a theory of mind.(1) This article has two goals: (1) to apply four familiar definitions or characterizations of integrity to the case of moderate to severe autism, and (2) to examine whether autistic integrity does provide the moral justification Barnbaum seeks.
Saunders, Sue; Butts, Jennifer Lease
2011-01-01
Integrity is one of those essential yet highly ambiguous concepts. For the purpose of this chapter, integrity is defined as that combination of both attributes and actions that makes entities appear to be whole and ethical, as well as consistent. Like the concepts of leadership or wisdom or community or collaboration, integrity is a key element of…
Microorganisms involved in MIC
Energy Technology Data Exchange (ETDEWEB)
Sorensen, K. [Danish Technological Institute (Denmark)
2011-07-01
Microbiologically influenced corrosion (MIC) is a widespread problem that is difficult to detect and assess because of its complex mechanism. This paper presents the involvement of microorganisms in MIC. Some of the mechanisms that cause MIC include hydrogen consumption, production of acids, anode-cathode formation and electron shuttling. A classic bio-corrosive microorganism in the oil and gas industry is sulphate-reducing prokaryotes (SRP). Methanogens also increase corrosion rates in metals. Some of the phylogenetic orders detected while studying SRP and methanogens are archaeoglobales, clostridiales, methanosarcinales and methanothermococcus. There were some implications, such as growth of SRP not being correlated with growth of methanogens; methanogens were included in MIC risk assessment. A few examples are used to display how microorganisms are involved in topside corrosion and microbial community in producing wells. From the study, it can be concluded that, MIC risk assessment includes system data and empirical knowledge of the distribution and number of microorganisms in the system.
Involved Node Radiation Therapy
DEFF Research Database (Denmark)
Maraldo, Maja V; Aznar, Marianne C; Vogelius, Ivan R
2012-01-01
PURPOSE: The involved node radiation therapy (INRT) strategy was introduced for patients with Hodgkin lymphoma (HL) to reduce the risk of late effects. With INRT, only the originally involved lymph nodes are irradiated. We present treatment outcome in a retrospective analysis using this strategy...... to 36 Gy). Patients attended regular follow-up visits until 5 years after therapy. RESULTS: The 4-year freedom from disease progression was 96.4% (95% confidence interval: 92.4%-100.4%), median follow-up of 50 months (range: 4-71 months). Three relapses occurred: 2 within the previous radiation field......, and 1 in a previously uninvolved region. The 4-year overall survival was 94% (95% confidence interval: 88.8%-99.1%), median follow-up of 58 months (range: 4-91 months). Early radiation therapy toxicity was limited to grade 1 (23.4%) and grade 2 (13.8%). During follow-up, 8 patients died, none from HL, 7...
Between Involvement and Detachment
DEFF Research Database (Denmark)
Thomasen, Gry
Between Involvement and Detachment takes grasp with the Johnson administration’s (1963-1969) perceptions of and responses to the Western European realignments. Arguing that the Johnson administration set out to maintain the American unilateralist position in the transatlantic relation, not just a...... the administration maintained. Despite changed circumstances, the Nixon administration’s relation with and perceptions of the European allies largely resemble the traditionalist view of the Johnson administration....
Joint involvement in Ochronosis
Biehl, Christoph; Thormann, U.; Madera, N.; Heiß, C
2016-01-01
Introduction: Ochronosis is a metabolic disorder that is usually associated with the typical brown-black colored urine and retention of phenol complexes in sclera and skin. Kidney and heart are also checked, the disease can also cause damage in these organs. The disease is less associated with degenerative changes in the joints of the limbs and the spine. Methods: We report on the progress of a patient with documented family history on alcaptonuria and joint involvement. In the age of 69 ...
Involvement Without Participation?
DEFF Research Database (Denmark)
Olsén, Peter
2012-01-01
The article presents a case study of a knowledge-intensive company that launched a 2-year project to improve their psychosocial working environment. All parties agreed on the project, and the methods used aimed to promote the involvement of the employees. Surprisingly, the psychosocial working...... and participation. In order to develop a more sustainable and viable psychosocial working environment, a broader and more democratic notion of organisational learning and managing is proposed....
DEFF Research Database (Denmark)
Petersson, Eva
2005-01-01
the theoretical foundations of play and learning. In this presentation, we explore pedagogical potentials of new technologies and traditional toys integrated into a physical and virtual toy (hereinafter called integrated toy) with specific focus on the open-ended toy and non-formal learning. The integrated toy...... and interaction with the integrated toy as a virtual experience without attachment or wearable on the body, which in context would not be appropriate. In the field of rehabilitation integrated toys are still at an embryonic stage and as such an under used resource for rehabilitation. Qualitative method...
Banner, Davina; Grant, Lyle G
2011-01-01
The need for quality nursing research to promote evidence-based practice and optimize patient care is well recognized. This is particularly pertinent in cardiovascular nursing, where cardiovascular disease continues to be the leading cause of morbidity and mortality worldwide (World Health Organization, 2007). Across the spectrum of academic, clinical, and health care administration nursing roles, research remains fundamental to bridging theory, practice, and education (LoBiondo-Wood, Haber, Cameron, & Singh, 2009). Despite recognition of the importance of nursing research, the gap between research and practice continues to be an ongoing issue (Funk, Tornquist, & Champagne, 1995; Pettengill, Gillies, & Clark, 1994; Rizzuto, Bostrom, Suterm, & Chenitz, 1994; Rolfe, 1998). Nurses are appropriately situated to contribute to research that improves clinical outcomes and health service delivery. However, the majority of nurses in clinical practice do not have a significant research component structured into their nursing role. In this research column, the authors outline the importance of nurses being engaged in research and present some different levels of involvement that nurses may assume. A continuum of nursing research involvement includes asking researchable questions, being a savvy consumer of research evidence, finding your own level of research involvement, and aspiring to lead.
Public Data Integration with WebSmatch
Coletta, R; Valduriez, P; Frisch, C; Ngo, D; Bellahsene, Z
2012-01-01
Integrating open data sources can yield high value information but raises major problems in terms of metadata extraction, data source integration and visualization of integrated data. In this paper, we describe WebSmatch, a flexible environment for Web data integration, based on a real, end-to-end data integration scenario over public data from Data Publica. WebSmatch supports the full process of importing, refining and integrating data sources and uses third party tools for high quality visualization. We use a typical scenario of public data integration which involves problems not solved by currents tools: poorly structured input data sources (XLS files) and rich visualization of integrated data.
Stochastic Lie group integrators
Malham, Simon J A
2007-01-01
We present Lie group integrators for nonlinear stochastic differential equations with non-commutative vector fields whose solution evolves on a smooth finite dimensional manifold. Given a Lie group action that generates transport along the manifold, we pull back the stochastic flow on the manifold to the Lie group via the action, and subsequently pull back the flow to the corresponding Lie algebra via the exponential map. We construct an approximation to the stochastic flow in the Lie algebra via closed operations and then push back to the Lie group and then to the manifold, thus ensuring our approximation lies in the manifold. We call such schemes stochastic Munthe-Kaas methods after their deterministic counterparts. We also present stochastic Lie group integration schemes based on Castell--Gaines methods. These involve using an underlying ordinary differential integrator to approximate the flow generated by a truncated stochastic exponential Lie series. They become stochastic Lie group integrator schemes if...
Energy Technology Data Exchange (ETDEWEB)
NONE
1995-04-01
Integrated assessment can be used to evaluate and clarify resource management policy options and outcomes for decision makers. The defining characteristics of integrated assessment are (1) focus on providing information and analysis that can be understood and used by decision makers rather than for merely advancing understanding and (2) its multidisciplinary approach, using methods, styles of study, and considerations from a broader variety of technical areas than would typically characterize studies produced from a single disciplinary standpoint. Integrated assessment may combine scientific, social, economic, health, and environmental data and models. Integrated assessment requires bridging the gap between science and policy considerations. Because not everything can be valued using a single metric, such as a dollar value, the integrated assessment process also involves evaluating trade-offs among dissimilar attributes. Scientists at Oak Ridge National Laboratory (ORNL) recognized the importance and value of multidisciplinary approaches to solving environmental problems early on and have pioneered the development of tools and methods for integrated assessment over the past three decades. Major examples of ORNL`s experience in the development of its capabilities for integrated assessment are given.
Local identities involving Jacobi elliptic functions
Indian Academy of Sciences (India)
Avinash Khare; Arul Lakshminarayan; Uday Sukhatme
2004-06-01
We derive a number of local identities involving Jacobi elliptic functions and use them to obtain several new results. First, we present an alternative, simpler derivation of the cyclic identities discovered by us recently, along with an extension to several new cyclic identities. Second, we obtain a generalization to cyclic identities in which successive terms have a multiplicative phase factor exp$(2i=s)$, where $s$ is any integer. Third, we systematize the local identities by deriving four local `master identities' analogous to the master identities for the cyclic sums discussed by us previously. Fourth, we point out that many of the local identities can be thought of as exact discretizations of standard non-linear differential equations satisfied by the Jacobi elliptic functions. Finally, we obtain explicit answers for a number of definite integrals and simpler forms for several indefinite integrals involving Jacobi elliptic functions.
Involvement in Physical Activity
Directory of Open Access Journals (Sweden)
James Gavin
2013-04-01
Full Text Available A total of 1,096 adolescents participated in 123 focus groups regarding the perceived outcomes of their involvement in sports and physical activity (PA. The groups, segmented by grade level, sex, and school types, were conducted in both public and private high schools in Montreal, Quebec. We sought to understand, through the participants’ own words, their perception of the outcome matrix of involvement in sports and PA. Focus group questions emphasized changes that adolescents associated with such engagement. In particular, participants were asked how sports and PA might influence behaviors, emotional states, personal characteristics, and other outcomes. Twelve themes were identified in the responses: Positive Health and Physical Changes (18.5%, Activity-Related Positive Emotions (15.6%, and Personal Learning (11.3% were most prevalent in the discussions. A cluster of deeper personal changes thematically described as Self-Identity, Autonomy, and Positive Character Development accounted for another 16.5% of the responses. Relatively few commentaries emphasized negative effects (7.1%. Converting the proportions of qualitative data into a quantitative index allowed us to analyze potential differences in emphasis according to sex, age, and school type. Though a few significant findings emerged, the larger pattern was of a uniform perceptual map across the variables for this adolescent sample. Implications drawn from this investigation highlight the need to clearly articulate concrete pathways to positive nonphysical changes (e.g., mood states, autonomy, positive character development from engagements in sports and PA.
Interorganisational Integration
DEFF Research Database (Denmark)
Lyngsø, Anne Marie; Godtfredsen, Nina Skavlan; Frølich, Anne
2016-01-01
at a university hospital in the Capital Region of Denmark. RESULTS AND DISCUSSION: Our results can be grouped into five influencing areas for interorganisational integration: communication/information transfer, committed leadership, patient engagement, the role and competencies of the general practitioner......INTRODUCTION: Despite many initiatives to improve coordination of patient pathways and intersectoral cooperation, Danish health care is still fragmented, lacking intra- and interorganisational integration. This study explores barriers to and facilitators of interorganisational integration...... and organisational culture. Proposed solutions to barriers in each area hold the potential to improve care integration as experienced by individuals responsible for supporting and facilitating it. Barriers and facilitators to integrating care relate to clinical, professional, functional and normative integration...
Barca, Giuseppe M J; Gill, Peter M W
2016-01-01
Explicitly-correlated F12 methods are becoming the first choice for high-accuracy molecular orbital calculations, and can often achieve chemical accuracy with relatively small gaussian basis sets. In most calculations, the many three- and four-electron integrals that formally appear in the theory are avoided through judicious use of resolutions of the identity (RI). However, in order not to jeopardize the intrinsic accuracy of the F12 wave function, the associated RI auxiliary basis set must be large. Here, inspired by the Head-Gordon-Pople (HGP) and PRISM algorithms for two-electron integrals, we present an algorithm to compute directly three-electron integrals over gaussian basis functions and a very general class of three-electron operators, without invoking RI approximations. A general methodology to derive vertical, transfer and horizontal recurrence relations is also presented.
Moiseiwitsch, B L
2005-01-01
Two distinct but related approaches hold the solutions to many mathematical problems--the forms of expression known as differential and integral equations. The method employed by the integral equation approach specifically includes the boundary conditions, which confers a valuable advantage. In addition, the integral equation approach leads naturally to the solution of the problem--under suitable conditions--in the form of an infinite series.Geared toward upper-level undergraduate students, this text focuses chiefly upon linear integral equations. It begins with a straightforward account, acco
DEFF Research Database (Denmark)
Liebst, Lasse Suonperä; Ejbye-Ernst, Peter; Heinskou, Marie Bruvik
patrons plays in bouncers’ use of violence. To address this gap, we offer a micro-interactional analysis of violent behavior of bouncers. We observed video surveillance footage of naturally occurring barroom conflicts involving bouncers. A quantitative analysis shows that violence is relatively uncommon......, and when it occurs, it is associated with interactions where bouncers are a party to the conflict, compared to situations where they intervene as a third party. Further, a visual analysis of emotional cues identifies anger as a plausible mechanism leading bouncers to practice violent aggression. Thus......, adding to the situational and cultural interpretations in the literature, this study highlights interactional structures as a feature influencing the likelihood of violent bouncer behavior. In considering the implications of our study, we discuss strengths and weaknesses of applying video data analysis...
Effectiveness of citizen involvement
Energy Technology Data Exchange (ETDEWEB)
Robinson, L. [Prince William Sound Regional Citizen' s Advisory Council, Anchorage, AK (United States)
2006-07-01
This paper reviewed the rise of citizen involvement in industry that affects their community. Following the Exxon Valdez oil spill (EVOS) in 1989, the Oil Pollution Act of 1990 provided funding by industry for a citizens group to provide oversite of the Alyeska Pipeline Service Agency terminal and associated tankers. That role is currently filled by the Prince William Sound Regional Citizen's Advisory Council, a volunteer organization that represents communities that were affected by the EVOS. The history of the Prince William Sound Regional Citizen's Advisory Council was discussed along with its structure, funding and overview of projects and research into safer transportation of oil, better oil spill response capabilities and improved environmental protection practices. Some of the successes involving citizen input include the requirement that all tankers going into Prince William Sound be double hull by 2015; a world-class system of tugs escorting tankers in Prince William Sound; installation of an ice-detection radar on a small island near the site of the EVOS; a guidebook for communities affected by man-made disasters; identification of nearshore locations that should be the first to be protected in the case of another spill; and, the installation of a system to capture crude oil vapors when tankers take on cargo. Other projects underway include the study of invasive species that can be transported in the ballast water of tankers, efficacy of dispersants, soil contamination at the tanker loading site, emissions of hazardous air pollutants from ballast water treatment processes, and continual review of emergency response plans. In the 17 years since the formation of the Prince William Sound Regional Citizen's Advisory Council, it has been shown that communication and transparency are the keys to solving complacency, which is believed to have been a contributing factor to the EVOS. 3 refs.
Sheng, Hua; Frei, Heinz
2016-08-10
In the search for the two-electron-reduced intermediate of the tetraaza catalyst [Co(II)N4H(MeCN)](2+) (N4H = 2,12-dimethyl-3,7,11,17-tetraazabicyclo[11.3.1]heptadeca-1(17),2,11,13,15-pentaene) for CO2 reduction and elementary steps that result in the formation of CO product, rapid-scan FT-IR spectroscopy of the visible-light-sensitized catalysis, using Ir(ppy)3 in wet acetonitrile (CD3CN) solution, led to the observation of two sequential intermediates. The initially formed one-electron-reduced [Co(I)N4H](+)-CO2 adduct was converted by the second electron to a transient [Co(I)N4H](+)-CO2(-) complex that spontaneously converted CO2 to CO in a rate-limiting step on the second time scale in the dark under regeneration of the catalyst (room temperature). The macrocycle IR spectra of the [Co(I)N4H](+)-CO2(-) complex and the preceding one-electron [Co(I)N4H](+)-CO2 intermediate show close similarity but distinct differences in the carboxylate modes, indicating that the second electron resides mainly on the CO2 ligand. Vibrational assignments are corroborated by (13)C isotopic labeling. The structure and stability of the two-electron-reduced intermediate derived from the time-resolved IR study are in good agreement with recent predictions by DFT electronic structure calculations. This is the first observation of an intermediate of a molecular catalyst for CO2 reduction during the bond-breaking step producing CO. The reaction pathway for the Co tetraaza catalyst uncovered here suggests that the competition between CO2 reduction and proton reduction of a macrocyclic multi-electron catalyst is steered toward CO2 activation if the second electron is directly captured by an adduct of CO2 and the one-electron-reduced catalyst intermediate.
Energy Technology Data Exchange (ETDEWEB)
Fleming, Barry D. [School of Chemistry, Monash University, Wellington Rd, Clayton, Victoria 3800 (Australia)], E-mail: barry.fleming@sci.monash.edu.au; Bond, Alan M. [School of Chemistry, Monash University, Wellington Rd, Clayton, Victoria 3800 (Australia)], E-mail: alan.bond@sci.monash.edu.au
2009-04-01
The free-base porphyrin, 5,10,15,20-tetrakis(1-methyl-4-pyridyl)-21H,23H-porphine (H{sub 2}TMPyP), adsorbs onto a basal-plane graphite electrode. Under DC cyclic voltammetric conditions, the fully protonated dication, [H{sub 4}TMPyP(0)]{sup 2+}, undergoes an apparently close to ideal surface-confined two-electron reduction to the neutral [H{sub 4}TMPyP(-II)] species when the supporting electrolyte consists of aqueous 1 M HCl and 1 M NaCl and coverages are sub-monolayer. The reversible potential calculated from the average of the oxidation and reduction peak potentials is 0.138 {+-} 0.002 V (vs Ag/AgCl, 3 M NaCl) whilst their separation {delta}E{sub p}, approaches 0 mV at slow scan rates, as expected theoretically for an ideal surface-confined electron transfer process. Comparisons of simulated and experimental data imply that the increase in {delta}E{sub p} observed at scan rates above 10 V s{sup -1} is consistent with uncompensated Ohmic IR{sub u} drop effects, and not limitations imposed by electron transfer kinetics. Analysis of fundamental and higher harmonic components derived from large-amplitude sine-wave AC voltammetry is consistent with a very fast electron transfer rate constant, k{sup 0}, in excess of 10{sup 6} s{sup -1} for the overall two-electron process. However, careful comparison with AC theory highlights minor levels of non-ideality not attributable to purely capacitative background or uncompensated resistance effects. These are particularly evident when greater than monolayer surface coverages are employed. It is likely that subtle contributions from heterogeneity in the adsorbed layer and complexities in the reaction mechanism are present in this close to ideal surface-confined process, but they are more readily detected under conditions of large-amplitude Fourier transformed AC cyclic voltammetry than with the conventionally used DC cyclic format.
DEFF Research Database (Denmark)
Lenau, Torben Anker
1999-01-01
A homepage on the internet with course material, lecture plan, student exercises, etc. Continuesly updated during the course Integrated Design (80402, 80403)......A homepage on the internet with course material, lecture plan, student exercises, etc. Continuesly updated during the course Integrated Design (80402, 80403)...
DEFF Research Database (Denmark)
Lenau, Torben Anker
1999-01-01
A homepage on the internet with course material, lecture plan, student exercises, etc. Continuesly updated during the course Integrated Design (80402, 80403)......A homepage on the internet with course material, lecture plan, student exercises, etc. Continuesly updated during the course Integrated Design (80402, 80403)...
Bauböck, Rainer
1995-01-01
from the Table of Contents: Migration and integration - Basic concepts and definitions; Immigration and Integration policies; The legal framework for integration; Dimension of social integration; Cultural integration; Conclusions;
DEFF Research Database (Denmark)
Axelsson, Runo
2013-01-01
an increasing lack of integration in the health and welfare system. In the 2000’s, there has been a re-centralisation through mergers of hospitals, regions and state agencies. It has become clear, however, that mergers do not promote integration but rather increase the bureaucratisation of the system. Model......Background: In Sweden, as in many other countries, there has been a succession of trends in the organisation of health care and other welfare services. These trends have had different implications for the integration of services in the health and welfare system. Aims: One aim is to discuss...... the implications of different organisational trends for the integration of health and welfare services. Another aim is to introduce a Swedish model of financial coordination as a flexible way to organise integration. Organisational trends: In the 1960’s there was an expansion of health and welfare services leading...
[Nail involvement in leprosy].
Belinchón Romero, I; Ramos Rincón, J M; Reyes Rabell, F
2012-05-01
Leprosy, a disease caused by Mycobacterium leprae, primarily affects the skin and nerves, but the nails are also involved in as many as 3 out of 4 patients .The factors that trigger nail changes in leprosy are numerous and include repeated trauma, neuropathy, vascular impairment, infections, lepra reactions, and the drugs used to manage the disease. The changes most often reported include subungual hematomas, onycholysis, onychauxis, onychogryphosis, pterygium unguis, and onychoheterotopia, most of which can be attributed to nerve damage and trauma. Furthermore, the acro-osteolysis that occurs in the advanced stages of the disease may present with brachyonychia, racquet nails, or even anonychia. Infections of the nail bed leading to paronychia and onychomycosis should also be taken into account in leprosy. Other typical changes include longitudinal striae, pitting, macrolunula, Terry nails, leukonychia, hapalonychia, and Beau lines. In this review, we describe the principal nail changes associated with leprosy. These changes, which are highly varied and diverse in origin, are in fact a reflection of the significant morbidity caused by M. leprae infection.
Measuring the degree of integration for an integrated service network
Directory of Open Access Journals (Sweden)
Chenglin Ye
2012-09-01
Full Text Available Background: Integration involves the coordination of services provided by autonomous agencies and improves the organization and delivery of multiple services for target patients. Current measures generally do not distinguish between agencies' perception and expectation. We propose a method for quantifying the agencies' service integration. Using the data from the Children's Treatment Network (CTN, we aimed to measure the degree of integration for the CTN agencies in York and Simcoe. Theory and Methods: We quantified the integration by the agreement between perceived and expected levels of involvement and calculated four scores from different perspectives for each agency. We used the average score to measure the global network integration and examined the sensitivity of the global score. Results: Most agencies' integration scores were less than 65%. As measured by the agreement between every other agency's perception and expectation, the overall integration of CTN in Simcoe and York was 44% (95% CI: 39% - 49% and 52% (95% CI: 48% - 56%, respectively. The sensitivity analysis showed that the global scores were robust. Conclusion: Our method extends existing measures of integration and possesses a good extent of validity. We can also apply the method in monitoring improvement and linking integration with other outcomes.
Measuring the degree of integration for an integrated service network
Directory of Open Access Journals (Sweden)
Chenglin Ye
2012-09-01
Full Text Available Background: Integration involves the coordination of services provided by autonomous agencies and improves the organization and delivery of multiple services for target patients. Current measures generally do not distinguish between agencies' perception and expectation. We propose a method for quantifying the agencies' service integration. Using the data from the Children's Treatment Network (CTN, we aimed to measure the degree of integration for the CTN agencies in York and Simcoe. Theory and Methods: We quantified the integration by the agreement between perceived and expected levels of involvement and calculated four scores from different perspectives for each agency. We used the average score to measure the global network integration and examined the sensitivity of the global score. Results: Most agencies' integration scores were less than 65%. As measured by the agreement between every other agency's perception and expectation, the overall integration of CTN in Simcoe and York was 44% (95% CI: 39% - 49% and 52% (95% CI: 48% - 56%, respectively. The sensitivity analysis showed that the global scores were robust. Conclusion: Our method extends existing measures of integration and possesses a good extent of validity. We can also apply the method in monitoring improvement and linking integration with other outcomes.
Energy Technology Data Exchange (ETDEWEB)
Sand, Andrew M.; Mazziotti, David A., E-mail: damazz@uchicago.edu [Department of Chemistry and The James Franck Institute, The University of Chicago, Chicago, Illinois 60637 (United States)
2015-10-07
Determination of the two-electron reduced density matrix (2-RDM) from the solution of the anti-Hermitian contracted Schrödinger equation (ACSE) yields accurate energies and properties for both ground and excited states. Here, we develop a more efficient method to solving the ACSE that uses second-order information to select a more optimal step towards the solution. Calculations on the ground and excited states of water, hydrogen fluoride, and conjugated π systems show that the improved ACSE algorithm is 10-20 times faster than the previous ACSE algorithm. The ACSE can treat both single- and multi-reference electron correlation with the initial 2-RDM from a complete-active-space self-consistent-field (CASSCF) calculation. Using the improved algorithm, we explore the relationship between truncation of the active space in the CASSCF calculation and the accuracy of the energy and 2-RDM from the ACSE calculation. The accuracy of the ACSE, we find, is less sensitive to the size of the active space than the accuracy of other wavefunction methods, which is useful when large active space calculations are computationally infeasible.
Patil, Mahendra P; Sunoj, Raghavan B
2006-11-07
A systematic investigation on the cycloreversion reaction of the cycloadduct formed between substituted cyclopentadiene and p-benzoquinone (1-19) is reported at the B3LYP/6-311+G**//B3LYP/6-31G* level of theory. The computed activation barrier exhibits a fairly high sensitivity to the nature of substituents at the C7-position. Gibbs free energy of activation for 1 and 19 are found to be 20.3 and 30.1 kcal mol(-1), respectively, compared to 7, which is estimated to be 24.7 kcal mol(-1). Quantitative analysis of the electronic effects operating in both the cycloadduct as well as the corresponding transition state for the retro Diels-Alder (rDA) reaction performed using the natural bond orbital (NBO) and atoms in molecule (AIM) methods have identified important two-electron stabilizing interactions. Among four major delocalizations, sigma(C7-X) to sigma*(C1-C5) [and to sigma*(C2-C6)] is identified as the key contributing factor responsible for ground state C1-C5 bond elongation, which in turn is found to be crucial in promoting the rDA reaction. A good correlation between the population of antibonding orbital [sigma*(C1-C5)] of the ground state cycloadduct and Gibbs free energy of activation is observed. The importance of factors that modulate ground state structural features in controlling the energetics of rDA reaction is described.
Sand, Andrew M; Mazziotti, David A
2015-10-01
Determination of the two-electron reduced density matrix (2-RDM) from the solution of the anti-Hermitian contracted Schrödinger equation (ACSE) yields accurate energies and properties for both ground and excited states. Here, we develop a more efficient method to solving the ACSE that uses second-order information to select a more optimal step towards the solution. Calculations on the ground and excited states of water, hydrogen fluoride, and conjugated π systems show that the improved ACSE algorithm is 10-20 times faster than the previous ACSE algorithm. The ACSE can treat both single- and multi-reference electron correlation with the initial 2-RDM from a complete-active-space self-consistent-field (CASSCF) calculation. Using the improved algorithm, we explore the relationship between truncation of the active space in the CASSCF calculation and the accuracy of the energy and 2-RDM from the ACSE calculation. The accuracy of the ACSE, we find, is less sensitive to the size of the active space than the accuracy of other wavefunction methods, which is useful when large active space calculations are computationally infeasible.
Multidrug toxicity involving sumatriptan.
Knittel, Jessica L; Vorce, Shawn P; Levine, Barry; Hughes, Rhome L; Bosy, Thomas Z
2015-01-01
A multidrug fatality involving sumatriptan is reported. Sumatriptan is a tryptamine derivative that acts at 5-HT(1B/1D) receptors and is used for the treatment of migraines. The decedent was a 21-year-old white female found dead in bed by her spouse. No signs of physical trauma were observed and a large number of prescription medications were discovered at the scene. Toxicological analysis of the central blood revealed sumatriptan at a concentration of 1.03 mg/L. Following therapeutic dosing guidelines, sumatriptan concentrations do not exceed 0.095 mg/L. Sumatriptan was isolated by solid-phase extraction and analyzed using liquid chromatography-tandem mass spectrometry in multiple reaction monitoring mode. A tissue distribution study was completed with the following concentrations measured: 0.61 mg/L in femoral blood, 0.56 mg/L in iliac blood, 5.01 mg/L in urine, 0.51 mg/kg in liver, 3.66 mg/kg in kidney, 0.09 mg/kg in heart, 0.32 mg/kg in spleen, 0.01 mg/kg in brain, 15.99 mg/kg in lung and 78.54 mg/45 mL in the stomach contents. Carisoprodol, meprobamate, fluoxetine, doxylamine, orphenadrine, dextromethorphan and hydroxyzine were also present in the blood at the following concentrations: 3.35, 2.36, 0.63, 0.19, 0.06, 0.55 and 0.16 mg/L. The medical examiner ruled the cause of death as acute mixed drug toxicity and the manner of death as accident.
McKean, Henry P
2005-01-01
This little book is a brilliant introduction to an important boundary field between the theory of probability and differential equations. -E. B. Dynkin, Mathematical Reviews This well-written book has been used for many years to learn about stochastic integrals. The book starts with the presentation of Brownian motion, then deals with stochastic integrals and differentials, including the famous Itô lemma. The rest of the book is devoted to various topics of stochastic integral equations, including those on smooth manifolds. Originally published in 1969, this classic book is ideal for supplemen
Energy Technology Data Exchange (ETDEWEB)
Nakicenovic, N.; Amann, M.; Fischer, G.
1995-12-31
Integrated assessment aims to develop a framework for the analysis of mitigation and adaption strategies to deal with the impacts of global change. It is a recent, rapidly evolving field, IIASA has been an active contributor to its development through in-house research as well as collaborative activities. The latter includes a series of influential conferences on economic aspects and integrated assessment of climate change, as well as the Energy Modeling Forum on integrated assessment models comparison, organized jointly with Stanford University. Various impacts including those of energy use are discussed. 8 refs., 1 fig.
DEFF Research Database (Denmark)
Agergaard, Sine; Sørensen, Jan Kahr
2010-01-01
Increased public funding, more governmental involvement and an emphasis on the instrumental values of physical activities have in general become characteristic of Western nations’ policies towards sport. Denmark is, however, a little different in that there is still little political intervention...... in sport, although sports clubs do get economic support and are seen as having the potential to solve crucial social issues. The purpose of this article is to analyse and discuss the ways in which the political assumption that sport can enhance social integration is reflected in the practical governance...... of integration issues in particular in sports clubs. The article is based on a local field study in which we interviewed 10 talented football players with ethnic minority backgrounds and eight coaches and club leaders from six different football clubs. Distinguishing between integration and assimilation...
DEFF Research Database (Denmark)
Knudsen, Lars Ramkilde; Wagner, David
2002-01-01
This paper considers a cryptanalytic approach called integral cryptanalysis. It can be seen as a dual to differential cryptanalysis and applies to ciphers not vulnerable to differential attacks. The method is particularly applicable to block ciphers which use bijective components only.......This paper considers a cryptanalytic approach called integral cryptanalysis. It can be seen as a dual to differential cryptanalysis and applies to ciphers not vulnerable to differential attacks. The method is particularly applicable to block ciphers which use bijective components only....
Cartier, Pierre; DeWitt-Morette, Cecile
2010-06-01
Acknowledgements; List symbols, conventions, and formulary; Part I. The Physical and Mathematical Environment: 1. The physical and mathematical environment; Part II. Quantum Mechanics: 2. First lesson: gaussian integrals; 3. Selected examples; 4. Semiclassical expansion: WKB; 5. Semiclassical expansion: beyond WKB; 6. Quantum dynamics: path integrals and operator formalism; Part III. Methods from Differential Geometry: 7. Symmetries; 8. Homotopy; 9. Grassmann analysis: basics; 10. Grassmann analysis: applications; 11. Volume elements, divergences, gradients; Part IV. Non-Gaussian Applications: 12. Poisson processes in physics; 13. A mathematical theory of Poisson processes; 14. First exit time: energy problems; Part V. Problems in Quantum Field Theory: 15. Renormalization 1: an introduction; 16. Renormalization 2: scaling; 17. Renormalization 3: combinatorics; 18. Volume elements in quantum field theory Bryce DeWitt; Part VI. Projects: 19. Projects; Appendix A. Forward and backward integrals: spaces of pointed paths; Appendix B. Product integrals; Appendix C. A compendium of gaussian integrals; Appendix D. Wick calculus Alexander Wurm; Appendix E. The Jacobi operator; Appendix F. Change of variables of integration; Appendix G. Analytic properties of covariances; Appendix H. Feynman's checkerboard; Bibliography; Index.
Institute of Scientific and Technical Information of China (English)
祁家能
2012-01-01
After going through the rising,developing and perfecting stages,the development of electronic reading rooms in college libraries now faces many new difficulties.So it is necessary to reconsider and reform the construction of the electronic reading room.It is advised to divide two electronic reading rooms into three areas which can offer free service,information retrieval service and special service respectively,so as to implement three kinds of management modes to meet the demands of different readers.The method is helpful to solve the development dilemma of the electronic reading rooms and give full play to the resources and facilities of the library.%高校图书馆电子阅览室从兴起、快速发展、成熟完善,到现在面临的诸多困境,促使我们对电子阅览室的建设要重新认识和进行理念创新。应该把两个电子阅览室分成辅助教学及读者自主学习区,信息检索学习区和个性化特色服务区三个区域,实行三种管理模式,满足不同读者的需求,走出电子阅览室发展的困境,使图书馆资源和设备发挥最大作用。
Integrated Reporting og Integrated Thinking
DEFF Research Database (Denmark)
Pontoppidan, Caroline Aggestam; Sonnerfeldt, Amanda
2017-01-01
I løbet af de sidste to måneder af 2016, havde vi mulighed for at deltage i to konferencer, med fokus på at udvikle og fremme ‘Integrated Reporting’ (IR) og ‘Integrated Thinking’. Denne artikel søger at videregive nogle af de interessante emner og spørgsmål, der blev drøftet ved disse to begivenh......I løbet af de sidste to måneder af 2016, havde vi mulighed for at deltage i to konferencer, med fokus på at udvikle og fremme ‘Integrated Reporting’ (IR) og ‘Integrated Thinking’. Denne artikel søger at videregive nogle af de interessante emner og spørgsmål, der blev drøftet ved disse...
Torrielli, Alessandro
2016-08-01
We review some essential aspects of classically integrable systems. The detailed outline of the sections consists of: 1. Introduction and motivation, with historical remarks; 2. Liouville theorem and action-angle variables, with examples (harmonic oscillator, Kepler problem); 3. Algebraic tools: Lax pairs, monodromy and transfer matrices, classical r-matrices and exchange relations, non-ultralocal Poisson brackets, with examples (non-linear Schrödinger model, principal chiral field); 4. Features of classical r-matrices: Belavin-Drinfeld theorems, analyticity properties, and lift of the classical structures to quantum groups; 5. Classical inverse scattering method to solve integrable differential equations: soliton solutions, spectral properties and the Gel’fand-Levitan-Marchenko equation, with examples (KdV equation, Sine-Gordon model). Prepared for the Durham Young Researchers Integrability School, organised by the GATIS network. This is part of a collection of lecture notes.
Williamson, JH
2014-01-01
This concise introduction to Lebesgue integration is geared toward advanced undergraduate math majors and may be read by any student possessing some familiarity with real variable theory and elementary calculus. The self-contained treatment features exercises at the end of each chapter that range from simple to difficult. The approach begins with sets and functions and advances to Lebesgue measure, including considerations of measurable sets, sets of measure zero, and Borel sets and nonmeasurable sets. A two-part exploration of the integral covers measurable functions, convergence theorems, co
Tricomi, Francesco Giacomo
1957-01-01
This classic text on integral equations by the late Professor F. G. Tricomi, of the Mathematics Faculty of the University of Turin, Italy, presents an authoritative, well-written treatment of the subject at the graduate or advanced undergraduate level. To render the book accessible to as wide an audience as possible, the author has kept the mathematical knowledge required on the part of the reader to a minimum; a solid foundation in differential and integral calculus, together with some knowledge of the theory of functions is sufficient. The book is divided into four chapters, with two useful
The Integrated Hazard Analysis Integrator
Morris, A. Terry; Massie, Michael J.
2009-01-01
Hazard analysis addresses hazards that arise in the design, development, manufacturing, construction, facilities, transportation, operations and disposal activities associated with hardware, software, maintenance, operations and environments. An integrated hazard is an event or condition that is caused by or controlled by multiple systems, elements, or subsystems. Integrated hazard analysis (IHA) is especially daunting and ambitious for large, complex systems such as NASA s Constellation program which incorporates program, systems and element components that impact others (International Space Station, public, International Partners, etc.). An appropriate IHA should identify all hazards, causes, controls and verifications used to mitigate the risk of catastrophic loss of crew, vehicle and/or mission. Unfortunately, in the current age of increased technology dependence, there is the tendency to sometimes overlook the necessary and sufficient qualifications of the integrator, that is, the person/team that identifies the parts, analyzes the architectural structure, aligns the analysis with the program plan and then communicates/coordinates with large and small components, each contributing necessary hardware, software and/or information to prevent catastrophic loss. As viewed from both Challenger and Columbia accidents, lack of appropriate communication, management errors and lack of resources dedicated to safety were cited as major contributors to these fatalities. From the accident reports, it would appear that the organizational impact of managers, integrators and safety personnel contributes more significantly to mission success and mission failure than purely technological components. If this is so, then organizations who sincerely desire mission success must put as much effort in selecting managers and integrators as they do when designing the hardware, writing the software code and analyzing competitive proposals. This paper will discuss the necessary and
Sweegers, C.C.G.
2014-01-01
The aim of this thesis was to characterize the neural mechanisms underlying memory integration. In chapter 2, we studied the neural underpinnings of regularity extraction across hippocampus-dependent episodic memories. We found higher connectivity between the hippocampus and the mPFC for the
DEFF Research Database (Denmark)
Merlo, Domenico Franco; Vahakangas, Kirsi; Knudsen, Lisbeth E.
2008-01-01
consent was obtained.Integrity is central to environmental health research searching for causal relations. It requires open communication and trust and any violation (i.e., research misconduct, including fabrication or falsification of data, plagiarism, conflicting interests, etc.) may endanger...
Graves, Eric
2013-01-01
This dissertation introduces the concept of Information Integrity, which is the detection and possible correction of information manipulation by any intermediary node in a communication system. As networks continue to grow in complexity, information theoretic security has failed to keep pace. As a result many parties whom want to communicate,…
Sozio, Gerry
2009-01-01
Senior secondary students cover numerical integration techniques in their mathematics courses. In particular, students would be familiar with the "midpoint rule," the elementary "trapezoidal rule" and "Simpson's rule." This article derives these techniques by methods which secondary students may not be familiar with and an approach that…
Graves, Eric
2013-01-01
This dissertation introduces the concept of Information Integrity, which is the detection and possible correction of information manipulation by any intermediary node in a communication system. As networks continue to grow in complexity, information theoretic security has failed to keep pace. As a result many parties whom want to communicate,…
DEFF Research Database (Denmark)
Knudsen, Lars Ramkilde; Wagner, David
2002-01-01
This paper considers a cryptanalytic approach called integral cryptanalysis. It can be seen as a dual to differential cryptanalysis and applies to ciphers not vulnerable to differential attacks. The method is particularly applicable to block ciphers which use bijective components only....
Libcint: An efficient general integral library for Gaussian basis functions.
Sun, Qiming
2015-08-15
An efficient integral library Libcint was designed to automatically implement general integrals for Gaussian-type scalar and spinor basis functions. The library is able to evaluate arbitrary integral expressions on top of p, r and σ operators with one-electron overlap and nuclear attraction, two-electron Coulomb and Gaunt operators for segmented contracted and/or generated contracted basis in Cartesian, spherical or spinor form. Using a symbolic algebra tool, new integrals are derived and translated to C code programmatically. The generated integrals can be used in various types of molecular properties. To demonstrate the capability of the integral library, we computed the analytical gradients and NMR shielding constants at both nonrelativistic and 4-component relativistic Hartree-Fock level in this work. Due to the use of kinetically balanced basis and gauge including atomic orbitals, the relativistic analytical gradients and shielding constants requires the integral library to handle the fifth-order electron repulsion integral derivatives. The generality of the integral library is achieved without losing efficiency. On the modern multi-CPU platform, Libcint can easily reach the overall throughput being many times of the I/O bandwidth. On a 20-core node, we are able to achieve an average output 8.3 GB/s for C60 molecule with cc-pVTZ basis. © 2015 Wiley Periodicals, Inc.
Kakuda, Saya; Peterson, Ryan L; Ohkubo, Kei; Karlin, Kenneth D; Fukuzumi, Shunichi
2013-05-01
A copper complex, [(PV-tmpa)Cu(II)](ClO4)2 (1) [PV-tmpa = bis(pyrid-2-ylmethyl){[6-(pivalamido)pyrid-2-yl]methyl}amine], acts as a more efficient catalyst for the four-electron reduction of O2 by decamethylferrocene (Fc*) in the presence of trifluoroacetic acid (CF3COOH) in acetone as compared with the corresponding copper complex without a pivalamido group, [(tmpa)Cu(II)](ClO4)2 (2) (tmpa = tris(2-pyridylmethyl)amine). The rate constant (k(obs)) of formation of decamethylferrocenium ion (Fc*(+)) in the catalytic four-electron reduction of O2 by Fc* in the presence of a large excess CF3COOH and O2 obeyed first-order kinetics. The k(obs) value was proportional to the concentration of catalyst 1 or 2, whereas the k(obs) value remained constant irrespective of the concentration of CF3COOH or O2. This indicates that electron transfer from Fc* to 1 or 2 is the rate-determining step in the catalytic cycle of the four-electron reduction of O2 by Fc* in the presence of CF3COOH. The second-order catalytic rate constant (k(cat)) for 1 is 4 times larger than the corresponding value determined for 2. With the pivalamido group in 1 compared to 2, the Cu(II)/Cu(I) potentials are -0.23 and -0.05 V vs SCE, respectively. However, during catalytic turnover, the CF3COO(-) anion present readily binds to 2 shifting the resulting complex's redox potential to -0.35 V. The pivalamido group in 1 is found to inhibit anion binding. The overall effect is to make 1 easier to reduce (relative to 2) during catalysis, accounting for the relative k(cat) values observed. 1 is also an excellent catalyst for the two-electron two-proton reduction of H2O2 to water and is also more efficient than is 2. For both complexes, reaction rates are greater than for the overall four-electron O2-reduction to water, an important asset in the design of catalysts for the latter.
Sacroiliac joint involvement in psoriasis.
Kaçar, Cahit; Sezer, Ilhan; Kocabaş, Hilal; Cay, Hasan Fatih; Cevikol, Can; Alpsoy, Erkan; Melikoğlu, Meltem Alkan; Akman, Ayşe
2010-07-01
Psoriasis is a skin disorder that is associated with arthritis. Sacroiliac joint involvement is considered to be less frequent than the other types of psoriatic arthritis. Additionally, the psoriatic sacroiliitis is considered to be asymmetric in general. We aimed to define the frequency and type of sacroiliac involvement in patients with psoriasis. Patients with psoriasis were included the study. Characteristics of skin, nail and articular involvement were noted. Psoriasis area and severity index was calculated. Antero-posterior pelvic X-rays were obtained and graded by two rheumatologists and a radiologist independently. One hundred and thirty-three patients were included. Thirty-seven of patients (27%) have articular involvement symptomatically. The sacroiliac joint involvement was observed in 34 (26%) of patients. More than one-half of sacroiliac involvement was bilateral while less than one-half was in symptomatic patients regarding sacroiliitis. Fifty-seven percentages of all patients have psoriatic nail involvement. Sacroiliac joint involvement did not show any significant association with psoriatic nail involvement or the severity of skin disease. We found higher frequency of sacroiliac joint involvement and bilateral sacroiliitis in patients with psoriasis. This is in contrast to present information about the association of psoriasis and sacroiliitis. These findings need confirmation by further studies and with more sophisticated techniques such as magnetic resonance imaging.
Geophysical interpretation using integral equations
Eskola, L
1992-01-01
Along with the general development of numerical methods in pure and applied to apply integral equations to geophysical modelling has sciences, the ability improved considerably within the last thirty years or so. This is due to the successful derivation of integral equations that are applicable to the modelling of complex structures, and efficient numerical algorithms for their solution. A significant stimulus for this development has been the advent of fast digital computers. The purpose of this book is to give an idea of the principles by which boundary-value problems describing geophysical models can be converted into integral equations. The end results are the integral formulas and integral equations that form the theoretical framework for practical applications. The details of mathematical analysis have been kept to a minimum. Numerical algorithms are discussed only in connection with some illustrative examples involving well-documented numerical modelling results. The reader is assu med to have a back...
Directory of Open Access Journals (Sweden)
Yeşim ULUSU
2016-01-01
Full Text Available The concept of “Involvement” is based on social psychology and specially attitude and attitude change subjects in the area of persuasive communication. The conceptualization of the “involvement” as a phe- nomenon was started to construct especially during the years between 1965-1980 when “involvement” was discussed in many areas of social sciences related to human behavior such as marketing, consumer behavior and advertising with its different dimensions.
ULUSU, Yeşim
2016-01-01
The concept of “Involvement” is based on social psychology and specially attitude and attitude change subjects in the area of persuasive communication. The conceptualization of the “involvement” as a phe- nomenon was started to construct especially during the years between 1965-1980 when “involvement” was discussed in many areas of social sciences related to human behavior such as marketing, consumer behavior and advertising with its different dimensions.
Monoarticular Hip Involvement in Pseudogout
Directory of Open Access Journals (Sweden)
Figen Kocyigit
2015-01-01
Full Text Available Pseudogout is the acutest form of arthritis in the elderly. Although clinical manifestations vary widely, polyarticular involvement is typical mimicking osteoarthritis or rheumatoid arthritis. Monoarticular involvement is relatively rare and is generally provoked by another medical condition. There are reported cases of hip involvement by pseudogout in monoarticular form. However, all of the cases were presented as septic arthritis. In this report, we present a case of monoarticular hip involvement mimicking soft tissue abscess. We confirmed the pseudogout diagnosis after ultrasonographic evaluation of the involved hip joint and pathological and biochemical analysis of synovial fluid analysis. Diagnosis is important to avoid unnecessary medical and surgical treatment in cases of the bizarre involvement of hip in pseudogout.
European Integration and Globalization
Directory of Open Access Journals (Sweden)
Diana Bobica
2010-06-01
Full Text Available According to many, the term globalization is able to explain any phenomenon whatsoever, be it positive or negative, that takes place within the global social system. It seems like a sort of magical formula, which is to be found in the speeches of all sorts of people, be they economists, politicians, businessmen or sociologists. However this magical formula of globalization has its limitations, since it encompasses a certain amount of quibbling, beyond which not many can pass. In the context of globalization there appears the question on its role in the process of European integration. Is European integration a part of this global process or, quite on the contrary, does it present certain distinctive features, as it moulds itself differently from the globalization phenomenon? A clear-cut answer seems difficult because of the various aspects involved. Not only the general phenomenon of globalization, but also the economic integration on European level is based on the liberalization of markets and on the opening of national economies towards the exterior,having as direct consequence the intensification of trade exchanges. If from a global point of view one may talk of a market fundamentalism in that the market principles know no boundary, European integration on the other hand implies not only market economy, but also a guided and monitored action of Member Statesaccording to the needs of the whole entity, also taking into consideration - as far as possible – all aspects and consequences on social level.
Skin involvement in Dupuytren's disease.
Wade, R.; Igali, L; Figus, A
2016-01-01
Whether the palmar skin has a role in the development, propagation or recurrence of Dupuytren's disease remains unclear. Clinical assessment for skin involvement is difficult and its correlation with histology uncertain. We prospectively biopsied the palmar skin of consecutive patients undergoing single digit fasciectomy (for primary Dupuytren's disease without clinically involved skin) and dermofasciectomy (for clinically involved skin or recurrence) in order to investigate this relationship...
Measure, integral and probability
Capiński, Marek
2004-01-01
Measure, Integral and Probability is a gentle introduction that makes measure and integration theory accessible to the average third-year undergraduate student. The ideas are developed at an easy pace in a form that is suitable for self-study, with an emphasis on clear explanations and concrete examples rather than abstract theory. For this second edition, the text has been thoroughly revised and expanded. New features include: · a substantial new chapter, featuring a constructive proof of the Radon-Nikodym theorem, an analysis of the structure of Lebesgue-Stieltjes measures, the Hahn-Jordan decomposition, and a brief introduction to martingales · key aspects of financial modelling, including the Black-Scholes formula, discussed briefly from a measure-theoretical perspective to help the reader understand the underlying mathematical framework. In addition, further exercises and examples are provided to encourage the reader to become directly involved with the material.
DEFF Research Database (Denmark)
Jørgensen, Michael; Nielsen, M. W.; Strømann-Andersen, Jakob Bjørn
2011-01-01
This paper presents a case study of the implementation of integrated design in an actual architectural competition. The design process was carried out at a highly esteemed architectural office and attended by both engineers and architects working towards mutual goals of architectural excellence......, low-energy consumption, and high-quality indoor environment. We use this case study to investigate how technical knowledge about building performance can be integrated into the conceptual design stage. We have selected certain points during the design process that represented design challenges...... and describe the decision process. Specific attention is given to how the engineering input was presented and how it was able to facilitate the design development. Site and context, building shape, organization of functions and HVAC-systems were all included to obtain a complete picture of the building...
On generalization of an integral inequality and its applications
Directory of Open Access Journals (Sweden)
Ghulam Farid
2015-12-01
Full Text Available In this paper, we give generalization of an integral inequality. We find its applications in fractional calculus by involving different kinds of fractional integral operators, for example Riemann–Liouville fractional integral, Caputo fractional derivative, Canavati fractional derivative and Widder derivative, Saigo fractional integral operator, etc.
Symbolism in European Integration
DEFF Research Database (Denmark)
Manners, Ian
2011-01-01
Ernst Haas observed over fifty years ago that ‘United Europe' is a resilient, adaptable, unifying, and yet unspecified symbol'. It is precisely this adaptability and ambiguity that has ensures the continuing importance of European studies as a means of understanding ‘the remarkable social...... of social transformation involved' (Calhoun 2003: 18). This article will consider the role of symbolism in European integration as part of answering Craig Calhoun's call for a means of transcending specific regimes of analysis in order to advance European studies....
Citizen Involvement in Public Television.
Wenner, Lawrence A.
The purpose of this study was to evaluate the amount and quality of citizen involvement in public television. From the perspective of the "average citizen," the concept of involvement is considered with regard to the Carnegie Commission, the Corporation for Public Broadcasting (CPB) borad of directors, the National Citizens Committee for…
Preparing Teachers for Parent Involvement.
Safran, Daniel
This paper examines the potential impact of parent involvement in the formal education of their children and suggests ways that teacher education can be restructured to prepare teachers to work with parents. This paper attempts to answer five questions: (1) Why should parents be involved in the formal education of their children? (2) Why should…
Parental Involvement and Academic Achievement
Goodwin, Sarah Christine
2015-01-01
This research study examined the correlation between student achievement and parent's perceptions of their involvement in their child's schooling. Parent participants completed the Parent Involvement Project Parent Questionnaire. Results slightly indicated parents of students with higher level of achievement perceived less demand or invitations…
Involvement of inositol in reproduction.
Beemster, P.; Groenen, P.; Steegers-Theunissen, R.P.M.
2002-01-01
Inositol is involved in several aspects of reproduction. It affects overall embryogenesis, may prevent neural tube defects, and stimulates the production of lung surfactant. This article will review the involvement of inositol in reproduction. After describing the biologic function of inositol and i
Direct Employee Involvement Quality (DEIQ)
Torka, Nicole; Woerkom, van Marianne; Looise, Jan-Kees
2008-01-01
This paper focuses on one aspect of human resource management (HRM) that is important for innovative employee behaviour: direct employee involvement quality (DEIQ). However, research has also shown that employee involvement is often in serious need of improvement. This paper presents evidence from t
Parental Involvement and Academic Achievement
Goodwin, Sarah Christine
2015-01-01
This research study examined the correlation between student achievement and parent's perceptions of their involvement in their child's schooling. Parent participants completed the Parent Involvement Project Parent Questionnaire. Results slightly indicated parents of students with higher level of achievement perceived less demand or invitations…
Art Integration and Cognitive Development
Baker, Dawn
2013-01-01
The arts have long been valued for their aesthetic contributions to education, and studies have been conducted to demonstrate their contribution to academic performance in an attempt to justify their inclusion in the curriculum. Art integration involves learning core content subjects (math, reading, language, science, social studies) through the…
Using Dance To Integrate Exceptionalities.
Wolf, Geraldine A.; Launi, Barbara A.
This conference presentation handout describes a program which uses dance therapy to integrate special education students with various disabilities. The 6-week program at a middle school involved having a professional dancer teach students traditional and modern dance methods as a means of expressing emotions, followed by teams of students…
Benchmark values for molecular three-center integrals arising in the Dirac equation
Baǧcı, A.; Hoggan, P. E.
2015-10-01
Previous papers by the authors report that they obtained compact, arbitrarily accurate expressions for two-center, one- and two-electron relativistic molecular integrals expressed over Slater-type orbitals. In the present study, accuracy limits of expressions given are examined for three-center nuclear attraction integrals, which are one-electron, three-center integrals with no analytically closed-form expression. In this work new molecular auxiliary functions are used. They are obtained via Neumann expansion of the Coulomb interaction. The numerical global adaptive method is used to evaluate these integrals for arbitrary values of orbital parameters and quantum numbers. Several methods, such as Laplace expansion of Coulomb interaction, single-center expansion, and the Fourier transformation method, have previously been used to evaluate these integrals considering the values of principal quantum numbers in the set of positive integer numbers. This study of three-center integrals places no restrictions on quantum numbers in all ranges of orbital parameters.
Benchmark values for molecular three-center integrals arising in Dirac equation
Bagci, A
2015-01-01
The authors in their previous papers obtained compact, arbitrarily accurate expressions for two center one and two electron Dirac integrals expressed over Slater orbitals with noninteger principal quantum numbers. In this present study, the accuracy limits of given expressions is examined for three-center nuclear attraction integrals, which are the first integral set do not have analytically closed form relations. They are expressed through new molecular auxiliary functions obtained via Neumann expansion of Coulomb interaction. The numerical global adaptive method is used to evaluate these integrals for arbitrarily values of orbital parameters, principal quantum numbers in Slater orbitals. Several methods, such as Laplace expansion of Coulomb interaction, single center expansions, Fourier transformation methods, have been developed for evaluation of three-center integrals when integer principal quantum number is used. This is the first attempts to study the three-center integrals with noninteger Slater orbita...
Solution of multi-center molecular integrals of Slater-type orbitals
Tai, H.
1989-01-01
The troublesome multi-center molecular integrals of Slater-type orbitals (STO) in molecular physics calculations can be evaluated by using the Fourier transform and proper coupling of the two center exchange integrals. A numerical integration procedure is then readily rendered to the final expression in which the integrand consists of well known special functions of arguments containing the geometrical arrangement of the nuclear centers and the exponents of the atomic orbitals. A practical procedure was devised for the calculation of a general multi-center molecular integrals coupling arbitrary Slater-type orbitals. Symmetry relations and asymptotic conditions are discussed. Explicit expressions of three-center one-electron nuclear-attraction integrals and four-center two-electron repulsion integrals for STO of principal quantum number n=2 are listed. A few numerical results are given for the purpose of comparison.
Benchmark values for molecular three-center integrals arising in the Dirac equation.
Bağcı, A; Hoggan, P E
2015-10-01
Previous papers by the authors report that they obtained compact, arbitrarily accurate expressions for two-center, one- and two-electron relativistic molecular integrals expressed over Slater-type orbitals. In the present study, accuracy limits of expressions given are examined for three-center nuclear attraction integrals, which are one-electron, three-center integrals with no analytically closed-form expression. In this work new molecular auxiliary functions are used. They are obtained via Neumann expansion of the Coulomb interaction. The numerical global adaptive method is used to evaluate these integrals for arbitrary values of orbital parameters and quantum numbers. Several methods, such as Laplace expansion of Coulomb interaction, single-center expansion, and the Fourier transformation method, have previously been used to evaluate these integrals considering the values of principal quantum numbers in the set of positive integer numbers. This study of three-center integrals places no restrictions on quantum numbers in all ranges of orbital parameters.
Reine, Simen; Tellgren, Erik; Helgaker, Trygve
2007-09-14
Utilizing the fact that solid-harmonic combinations of Cartesian and Hermite Gaussian atomic orbitals are identical, a new scheme for the evaluation of molecular integrals over solid-harmonic atomic orbitals is presented, where the integration is carried out over Hermite rather than Cartesian atomic orbitals. Since Hermite Gaussians are defined as derivatives of spherical Gaussians, the corresponding molecular integrals become the derivatives of integrals over spherical Gaussians, whose transformation to the solid-harmonic basis is performed in the same manner as for integrals over Cartesian Gaussians, using the same expansion coefficients. The presented solid-harmonic Hermite scheme simplifies the evaluation of derivative molecular integrals, since differentiation by nuclear coordinates merely increments the Hermite quantum numbers, thereby providing a unified scheme for undifferentiated and differentiated four-center molecular integrals. For two- and three-center two-electron integrals, the solid-harmonic Hermite scheme is particularly efficient, significantly reducing the cost relative to the Cartesian scheme.
A Romberg Integral Spreadsheet Calculator
Directory of Open Access Journals (Sweden)
Kim Gaik Tay
2015-04-01
Full Text Available Motivated by the work of Richardson’s extrapolation spreadsheet calculator up to level 4 to approximate definite differentiation, we have developed a Romberg integral spreadsheet calculator to approximate definite integral. The main feature of this version of spreadsheet calculator is a friendly graphical user interface developed to capture the needed information to solve the integral by Romberg method. Users simply need to enter the variable in the integral, function to be integrated, lower and upper limits of the integral, select the desired accuracy of computation, select the exact function if it exists and lastly click the Compute button which is associated with VBA programming written to compute Romberg integral table. The full solution of the Romberg integral table up to any level can be obtained quickly and easily using this method. The attached spreadsheet calculator together with this paper helps educators to prepare their marking scheme easily and assist students in checking their answers instead of reconstructing the answers from scratch. A summative evaluation of this Romberg Spreadsheet Calculator has been conducted by involving 36 students as sample. The data was collected using questionnaire. The findings showed that the majority of the students agreed that the Romberg Spreadsheet Calculator provides a structured learning environment that allows learners to be guided through a step-by-step solution.
Exploration of Team Integration in Spanish Multifamily Residential Building Construction
Pellicer, Eugenio; Sanz Benlloch, María Amalia; Esmaeili, B; MOLENAAR, KEITH ROBERT
2016-01-01
Project delivery team integration generally involves early involvement of general contractors and key specialty contractors in the design process. Team integration has been found to improve an owner’s probability of success. However, during difficult economic times, owners can forego early team involvement and move toward low bid procurement to take advantage of competitive markets. This study explores the performance of integrated teams in the Spanish multifamily building constructi...
National Research Council Canada - National Science Library
Burton, Jean
1991-01-01
...) prepared for each zone. The purpose of the integration method described in this document is to combine the sectoral diagnoses into an integrated document, to be used as a base document for consulting the various riverside parties involved...
Integration Rules for Scattering Equations
Baadsgaard, Christian; Bourjaily, Jacob L; Damgaard, Poul H
2015-01-01
As described by Cachazo, He and Yuan, scattering amplitudes in many quantum field theories can be represented as integrals that are fully localized on solutions to the so-called scattering equations. Because the number of solutions to the scattering equations grows quite rapidly, the contour of integration involves contributions from many isolated components. In this paper, we provide a simple, combinatorial rule that immediately provides the result of integration against the scattering equation constraints for any M\\"obius-invariant integrand involving only simple poles. These rules have a simple diagrammatic interpretation that makes the evaluation of any such integrand immediate. Finally, we explain how these rules are related to the computation of amplitudes in the field theory limit of string theory.
Integration rules for scattering equations
Baadsgaard, Christian; Bjerrum-Bohr, N. E. J.; Bourjaily, Jacob L.; Damgaard, Poul H.
2015-09-01
As described by Cachazo, He and Yuan, scattering amplitudes in many quantum field theories can be represented as integrals that are fully localized on solutions to the so-called scattering equations. Because the number of solutions to the scattering equations grows quite rapidly, the contour of integration involves contributions from many isolated components. In this paper, we provide a simple, combinatorial rule that immediately provides the result of integration against the scattering equation constraints fo any Möbius-invariant integrand involving only simple poles. These rules have a simple diagrammatic interpretation that makes the evaluation of any such integrand immediate. Finally, we explain how these rules are related to the computation of amplitudes in the field theory limit of string theory.
Some integral inequalities for logarithmically convex functions
Directory of Open Access Journals (Sweden)
Mevlüt Tunç
2014-07-01
Full Text Available The main aim of the present note is to establish new Hadamard like integral inequalities involving log-convex function. We also prove some Hadamard-type inequalities, and applications to the special means are given.
Ocular involvement in pemphigus vulgaris.
Akhyani, Maryam; Keshtkar-Jafari, Alireza; Chams-Davatchi, Cheyda; Lajevardi, Vahide; Beigi, Sara; Aghazadeh, Nessa; Rayati Damavandi, Maede; Arami, Shabnam
2014-07-01
Pemphigus vulgaris (PV) is an autoimmune disorder affecting the skin and mucous membranes. Ocular involvement in PV has been reported but its prevalence and clinical characteristics are not well defined. This prospective cross-sectional study of 103 PV patients was designed to determine the prevalence, clinical types and epidemiological trends of ocular involvement in a population of Iranian patients with PV. Ocular involvement was present in 17 (16.5%) patients. Conjunctivitis was the most prevalent type of ocular involvement (9/17, 52.9%), followed by erosion of the palpebral conjunctiva (7/17, 41.2%). Erosion of the bulbar conjunctiva was noted in only one patient (5.9%). The most commonly reported symptoms were eye irritation (76.5%) and redness (76.5%). No significant relation was found between ocular involvement and disease activity (partial remission or relapse). Mucoid discharge was significantly more common in patients with conjunctival erosions as compared to patients with conjunctivitis (P = 0.038). We conclude that ocular involvement is not rare in PV; 16.5% of PV patients develop ocular disease independent of the disease activity and extension. Conjunctivitis is the most common type of involvement, however, palpebral conjunctival erosion is more frequent than previously realized.
Road rage and collision involvement.
Mann, Robert E; Zhao, Jinhui; Stoduto, Gina; Adlaf, Edward M; Smart, Reginald G; Donovan, John E
2007-01-01
To assess the contribution of road rage victimization and perpetration to collision involvement. The relationship between self-reported collision involvement and road rage victimization and perpetration was examined, based on telephone interviews with a representative sample of 4897 Ontario adult drivers interviewed between 2002 and 2004. Perpetrators and victims of both any road rage and serious road rage had a significantly higher risk of collision involvement than did those without road rage experience. This study provides epidemiological evidence that both victims and perpetrators of road rage experience increased collision risk. More detailed studies of the contribution of road rage to traffic crashes are needed.
GOVERNMENT INVOLVEMENT IN CONSUMPTION BEHAVIOUR
Directory of Open Access Journals (Sweden)
CRISTINA ZAMFIR
2010-01-01
Full Text Available In this article, we will follow the involvement that the government has,through its expenses, on the consumption behavior. The involvement that the government has inthe consumption behavior is made through fees and taxes that are applied on income. Fees andtaxes are applied to the different forms of income but in this article we will be focused only onthe influence of them on wages. In order to analyze the involvement of government expenses onconsumption behavior an utility model will be used.
Students’ difficulties with integration in electricity
Directory of Open Access Journals (Sweden)
Dong-Hai Nguyen
2011-06-01
Full Text Available This study investigates the common difficulties that students in introductory physics experience when solving problems involving integration in the context of electricity. We conducted teaching-learning interviews with 15 students in a second-semester calculus-based introductory physics course on several problems involving integration. We found that although most of the students could recognize the need for an integral in solving the problem, they failed to set up the desired integral. We provide evidence that this failure can be attributed to students’ inability to understand the infinitesimal term in the integral and/or failure to understand the notion of accumulation of an infinitesimal physical quantity. This work supports and extends previous research on students’ difficulties with integration in physics.
[Hand involvement in systemic sclerosis].
Mouthon, Luc
2013-12-01
Hand involvement is very common in patients with systemic sclerosis and represents an important tool for the early diagnosis of the disease. Vascular involvement of the hands is at the forefront of systemic sclerosis, with Raynaud's phenomenon, which may be complicated by digital ulcers, digital necrosis causing pain, infection and significant disability. Joint inflammation can also be disabling and causes the occurrence of contractures and deformities resulting in a marked hand disability. Skin sclerosis involving fingers and hands leads to the occurrence of pain and functional impairment. Hand involvement contributes to 75 % of global disability in patients with systemic sclerosis. Only a comprehensive care, taking into account the vascular, skin and joint manifestations, including physical therapy if needed can improve hand function in patients with systemic sclerosis.
Abdominal Actinomycetoma With Lymphnode Involvement
Directory of Open Access Journals (Sweden)
Damisetty Rajetha
2004-01-01
Full Text Available Actinomycotic mycetoma of the anterior abdominal wall with inguinal lymphnode involvement, an exceedingly rare entity is described here with mycological histological features. Remarkable therapeutic response was noted with Welsh regimen.
User Involvement And Entrepreneurial Action
Directory of Open Access Journals (Sweden)
Eva Heiskanen
2007-01-01
Full Text Available Involving users in the innovation process is a subject of much research, experimentation, and debate. Less attention has been given to the limits to user involvement that ensue from specific organizational characteristics. This article explores barriers to the utilization of users’ input in two small companies developing interactive digital applications. We contrast our findings to earlier research involving large companies to identify features of entrepreneurial sensemaking and action that influence the utilization of users’ input. We find that the small companies follow a distinct action rationality, leading to rapid implementation of some user inputs, and defensiveness toward others. Both sets of data also reveal common features that are often overlooked in the literature. We reconceptualize user involvement as a form of interaction between users and innovating companies that is facilitated and constrained by micro-sociological processes, on the one hand, and the nature of the competitive environment, on the other.
Considerations for future education in integrative landscape research
Tress, G.; Tress, B.; Fry, G.; Opdam, P.F.M.; Ahern, J.F.; Antrop, M.; Hartig, T.; Hobbs, R.; Miller, D.; Silbernagel, J.M.; Winder, N.
2006-01-01
This chapter discusses challenges for PhD students involved in integrative landscape research. These challenges include terminology, epistemology, expectations, stakeholder involvement, organizational barriers, communicating and publishing, as well as career development. The chapter presents recomme
Patient involvement in hospital architecture
DEFF Research Database (Denmark)
Herriott, Richard
2017-01-01
This paper examines user-involvement in the process used to design new hospitals. Denmark is in the midst of a phase of hospital building. This recent experience is studied by means of expert interviews with senior practitioners involved in three projects. Examined thematically, the data covers......-studied area, design for hospitals. It highlights difficulties in applying the goals of user-centred design and Design for All in large projects....
PENDEKATAN INTEGRAL DALAM PSIKOTERAPI TRANSPERSONAL
Directory of Open Access Journals (Sweden)
Hendro Prabowo
2015-09-01
Full Text Available Consciousness has been a popular topic in transpersonal psychology although the reviews were more focused on level of consciousness and states of consciousness. Theories of consciousness level are heavily influenced by perenial phylosophy concerning universal elements of consciousness, that are body, mind, soul and spirit. Transpersonal psychology also integrates Western and Eastern approaches in explaining consciousness. Both traditions have a variety and richness of tehniques to reach the four level of body, mind, soul and spirit. Davis (2003 describes transpersonal psychology as psychology that fully integrates psychological concepts, theories, and methods with practices and subject matter of spiritual sciences. In other word, the integration involves both theoretical and practical domains. This paper describes transpersonal psychology’s efforts in integrating psychotherapy.
Lexical Integration of Novel Words without Sleep
Lindsay, Shane; Gaskell, M. Gareth
2013-01-01
Learning a new word involves integration with existing lexical knowledge. Previous work has shown that sleep-associated memory consolidation processes are important for the engagement of novel items in lexical competition. In 3 experiments we used spaced exposure regimes to investigate memory for novel words and whether lexical integration can…
Integrability conditions on Engel-type manifolds
Calin, Ovidiu; Chang, Der-Chen; Hu, Jishan
2015-09-01
We introduce the concept of Engel manifold, as a manifold that resembles locally the Engel group, and find the integrability conditions of the associated sub-elliptic system , . These are given by , . Then an explicit construction of the solution involving an integral representation is provided, which corresponds to a Poincaré-type lemma for the Engel's distribution.
Integrated device architectures for electrochromic devices
Energy Technology Data Exchange (ETDEWEB)
Frey, Jonathan Mack; Berland, Brian Spencer
2015-04-21
This disclosure describes systems and methods for creating monolithically integrated electrochromic devices which may be a flexible electrochromic device. Monolithic integration of thin film electrochromic devices may involve the electrical interconnection of multiple individual electrochromic devices through the creation of specific structures such as conductive pathway or insulating isolation trenches.
Integrating hospital and physician revenue cycle operations.
Lockett, Kevin M
2014-03-01
Standardized revenue cycle processes should be a key component of the coordinated care delivery strategy organizations will require to complete the transition to population health management. Integrating hospital and physician revenue cycle operations can help organizations better navigate new payment models, reduce costs, and improve value. The most comprehensive approach involves integrating patient access and registration, coding operations, and receivables management across different settings.
On a Volterra Stieltjes integral equation
Directory of Open Access Journals (Sweden)
P. T. Vaz
1990-01-01
Full Text Available The paper deals with a study of linear Volterra integral equations involving Lebesgue-Stieltjes integrals in two independent variables. The authors prove an existence theorem using the Banach fixed-point principle. An explicit example is also considered.
Multidimensional singular integrals and integral equations
Mikhlin, Solomon Grigorievich; Stark, M; Ulam, S
1965-01-01
Multidimensional Singular Integrals and Integral Equations presents the results of the theory of multidimensional singular integrals and of equations containing such integrals. Emphasis is on singular integrals taken over Euclidean space or in the closed manifold of Liapounov and equations containing such integrals. This volume is comprised of eight chapters and begins with an overview of some theorems on linear equations in Banach spaces, followed by a discussion on the simplest properties of multidimensional singular integrals. Subsequent chapters deal with compounding of singular integrals
Spent nuclear fuel project integrated schedule plan
Energy Technology Data Exchange (ETDEWEB)
Squires, K.G.
1995-03-06
The Spent Nuclear Fuel Integrated Schedule Plan establishes the organizational responsibilities, rules for developing, maintain and status of the SNF integrated schedule, and an implementation plan for the integrated schedule. The mission of the SNFP on the Hanford site is to provide safe, economic, environmentally sound management of Hanford SNF in a manner which stages it to final disposition. This particularly involves K Basin fuel.
Spent nuclear fuel project integrated schedule plan
Energy Technology Data Exchange (ETDEWEB)
Squires, K.G.
1995-03-06
The Spent Nuclear Fuel Integrated Schedule Plan establishes the organizational responsibilities, rules for developing, maintain and status of the SNF integrated schedule, and an implementation plan for the integrated schedule. The mission of the SNFP on the Hanford site is to provide safe, economic, environmentally sound management of Hanford SNF in a manner which stages it to final disposition. This particularly involves K Basin fuel.
Research on Integrated Green Supply Chain Management
Institute of Scientific and Technical Information of China (English)
DENG Lei; WANG Xu
2006-01-01
On the basis of the analyzing product life cycle and value chain management in green supply chain, integrated green supply chain is put forward and constructed which involve lean production, agile manufacturing and green supply chain. This integrated structure provides an effective method for resolving some questions such as cost, market, environment, etc. in enterprise. A case study is presented at the end of paper to demonstrate how integrated supply chain implemented successfully in enterprise.
Involving Motion Graphics in Spatial Experience Design
DEFF Research Database (Denmark)
Steijn, Arthur
2013-01-01
process, and therefore it should be constructed as such. Since the development of the design model has this double focus, I involve design students in design laboratories related to my practice as a teacher in visual communication design and production design. I also reflect on how an initial design...... conceptualization of various design elements in an analysis of the way in which these elements are integrated and used in the creation of particular experiences of space, atmosphere and artistic expression. On the basis of this analysis I present a preliminary construction of a design model including some design...... laboratory may be set-up and used. Finally I describe how this design lab can be used as a method for creating both practical knowledge of the manner in which the design model may be applied in actual design processes, as well as how these processes can be used for pointing out design elements or dimensions...
The Comptel project and Logica's involvement
McCormack, A.; Bains, N.; Jenkins, C.; Hall, R.; Jeanes, A.
1991-01-01
The scientific objectives of the application software development of the Compton Imaging Telescope (Comptel) project is described and Logica's specific involvement is detailed with respect to scientific, technical, and managerial aspects. Comptel is one of four instruments onboard the Gamma Ray Observatory (GRO), a NASA project, to be launched in March 1991. It will study gamma ray characteristics of point sources, diffuse emission from the galaxy, cosmic diffusion flux and broadened line emissions. It will also determine the direction of arrival as well as the energy of gamma ray photons from 1 to 30 MeV. Logica has played an active part in the writing of software requirements for the subsystems of GRO and subsequently the detailed design, code, test, and integration of these subsystems. Logica's roles include the development of a module calibration subsystem which includes the development of gamma ray burst software and pulsar analysis software both of which are discussed in detail.
Neurophysiological mechanisms involved in auditory perceptual organization
Directory of Open Access Journals (Sweden)
Aurélie Bidet-Caulet
2009-09-01
Full Text Available In our complex acoustic environment, we are confronted with a mixture of sounds produced by several simultaneous sources. However, we rarely perceive these sounds as incomprehensible noise. Our brain uses perceptual organization processes to independently follow the emission of each sound source over time. If the acoustic properties exploited in these processes are well-established, the neurophysiological mechanisms involved in auditory scene analysis have raised interest only recently. Here, we review the studies investigating these mechanisms using electrophysiological recordings from the cochlear nucleus to the auditory cortex, in animals and humans. Their findings reveal that basic mechanisms such as frequency selectivity, forward suppression and multi-second habituation shape the automatic brain responses to sounds in a way that can account for several important characteristics of perceptual organization of both simultaneous and successive sounds. One challenging question remains unresolved: how are the resulting activity patterns integrated to yield the corresponding conscious perceptsµ
DEFF Research Database (Denmark)
Dybbroe, Betina; Kamp, Annette
effectiveness and shared responsibility for care pathways. While NPM position users as consumers making their free choice, the user involvement paradigm underlines the users’ active participation in the mastering of their problems and disease. Research is scarce on this theme, and has until now primarily......In recent years user involvement has become a paradigm for transforming the health and social care sector. This development–also labelled empowerment, co-creation, partnership, patient-centeredness - is seen as a means to reform organizations in ways that enhance quality, economic cost...... addressed the way this paradigm affects the users, in specific sectors. However user involvement also affects working life. It may imply change and redistribution of tasks and identities between users and professionals, and may also transform the relations of care. In this paper we explore the possible...
Strategy Innovation with Employee Involvement
DEFF Research Database (Denmark)
Friis, Ole Uhrskov; Koch, Christian
2015-01-01
if the managers still dominate, some processes of direct involvement of employees occur, in particular when employees are asked to supplement overall strategic goals and when they directly shape several sub-strategies. Strategy practices found include strategy planning, an open space workshop and organised......The purpose of this article is to investigate how employees can be involved in strategy innovation processes and how new strategy practices (new tools and procedures) are used to change strategy praxis in order to sustain value creation. In the strategizing actions, we found that even...... strategy projects. Especially the latter two are important in facilitating the employee involvement. The case, however, also exhibits enterprise-situated praxises related to unplanned events, like the mitigation of taboos....
Involving Employees in Strategy innovation
DEFF Research Database (Denmark)
Friis, Ole Uhrskov; Koch, Christian
2011-01-01
some of its employees. Even if managers still dominate, some processes of direct involvement of employees occur. The employees are in particular active in supplementing overall strategic goals and directly shaping one sub strategy, that of ‘process’. Strategy practices include planning, Porterian......Strategy as a practice and continuous innovation approaches are combined to conceptualise dilemmas of short versus long term and to analyse a case of employee participation as a particular example of strategy innovation. The case is a medium size textile company developing its strategy involving...... and Balanced Score Card consultancy, an ‘open space’ workshop and organized strategy projects. Especially the latter two are important in facilitating the employee involvement. The case however also exhibit enterprise situated praxis’s like mitigation of taboos....
Gastrointestinal involvement in systemic sclerosis.
Savarino, Edoardo; Furnari, Manuele; de Bortoli, Nicola; Martinucci, Irene; Bodini, Giorgia; Ghio, Massimo; Savarino, Vincenzo
2014-10-01
Systemic sclerosis is an autoimmune chronic disease characterised by microvascular, muscular and immunologic abnormalities that lead to progressive and systemic deposition of connective tissue in the skin and internal organs. The gastrointestinal tract is often overlooked by physicians but it is the most affected organ after the skin, from the mouth to the anus. Indeed, 80% of SSc patients may present with gastrointestinal involvement. Gastrointestinal manifestations range from bloating and heartburn to dysphagia and anorectal dysfunction to severe weight loss and malabsorption. However, the gastrointestinal involvement is rarely the direct cause of death, but has great impact on quality of life and leads to several comorbidities that subsequently affect patients' survival. Treatments, including nutritional support and prokinetics provide limited benefits and do not arrest the progressive course of the disease, but earlier detection of gastrointestinal involvement may reduce the risk of complications such as malnutrition.
Gaussian and finite-element Coulomb method for the fast evaluation of Coulomb integrals.
Kurashige, Yuki; Nakajima, Takahito; Hirao, Kimihiko
2007-04-14
The authors propose a new linear-scaling method for the fast evaluation of Coulomb integrals with Gaussian basis functions called the Gaussian and finite-element Coulomb (GFC) method. In this method, the Coulomb potential is expanded in a basis of mixed Gaussian and finite-element auxiliary functions that express the core and smooth Coulomb potentials, respectively. Coulomb integrals can be evaluated by three-center one-electron overlap integrals among two Gaussian basis functions and one mixed auxiliary function. Thus, the computational cost and scaling for large molecules are drastically reduced. Several applications to molecular systems show that the GFC method is more efficient than the analytical integration approach that requires four-center two-electron repulsion integrals. The GFC method realizes a near linear scaling for both one-dimensional alanine alpha-helix chains and three-dimensional diamond pieces.
Integrable Bogoliubov Transform and Integrable Model
Institute of Scientific and Technical Information of China (English)
王宁
2003-01-01
By defining Bogoliubov transform as a function of parameters, the integrability of the Bogoliubov transform in parameter space is investigated. It is shown that integrable Bogoliubov transform is closely related to the known integrable model. The relation between the integrable Bogoliubov transform and geometric phase of vacuum induced by the Bogoliubov transform is also discussed.
[Heel involvement in rheumatoid polyarthritis].
Bouysset, M; Tebib, J G; Vianey, J C; Berthier, M; Nemoz, J C; Chaumentin, G; Schnepp, J; Llorca, G; Bouvier, M
1990-11-01
Calcaneus involvement during the course of RA is poorly known. A clinical and radiological study of 408 consecutive rheumatoid feet are then reported. If talalgia was seldomly noted (3.7 p. cent), plantar calcaneitis was found in 29.7 p. cent as plantar spur. Similarly, posterior exostosis was displayed in 30.5 p. cent of patients. These radiological abnormalities are increased in RA but appeared more as a consequence of the statical modification of the foot secondary to RA process than as a direct involvement. Logical orthopedic therapeutics are then proposed.
Multisystem involvement in neuromyelitis optica
Directory of Open Access Journals (Sweden)
Megan M Langille
2015-01-01
Full Text Available We describe a case of pediatric neuromyelitis optica (NMO with muscle and lung involvement in addition to central nervous system disease. Our patient initially presented with features of area postrema syndrome, then subsequently with optic neuritis. The patient also had recurrent hyperCKemia that responded to corticosteroids. Finally, axillary and hilar adenopathy with pulmonary consolidation were noted as well and responded to immunomodulation. Our case highlights multisystem involvement in NMO including non-infectious pulmonary findings which have not been described in the pediatric population previously.
Vertebral osteomyelitis without disc involvement
Energy Technology Data Exchange (ETDEWEB)
Kamani, I.; Syed, I.; Saifuddin, A. E-mail: asaifuddin@aol.com; Green, R.; MacSweeney, F
2004-10-01
Vertebral osteomyelitis is most commonly due to pyogenic or granulomatous infection and typically results in the combined involvement of the intervertebral disc and adjacent vertebral bodies. Non-infective causes include the related conditions of chronic recurrent multifocal osteomyelitis (CRMO) and SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome. Occasionally, these conditions may present purely within the vertebral body, resulting in various combinations of vertebral marrow oedema and sclerosis, destructive lesions of the vertebral body and pathological vertebral collapse, thus mimicking neoplastic disease. This review illustrates the imaging features of vertebral osteomyelitis without disc involvement, with emphasis on magnetic resonance imaging (MRI) findings.
Carlson, Warren; de Mello Koch, Robert; Lin, Hai
2011-03-01
In this article we study operators with a dimension Δ ˜ O( N) and show that simple analytic expressions for the action of the dilatation operator can be found. The operators we consider are restricted Schur polynomials. There are two distinct classes of operators that we consider: operators labeled by Young diagrams with two long columns or two long rows. The main complication in working with restricted Schur polynomials is in building a projector from a given S n+ m irreducible representation to an S n × S m irreducible representation (both specified by the labels of the restricted Schur polynomial). We give an explicit construction of these projectors by reducing it to the simple problem of addition of angular momentum in ordinary non-relativistic quantum mechanics. The diagonalization of the dilatation operator reduces to solving three term recursion relations. The fact that the recursion relations have only three terms is a direct consequence of the weak mixing at one loop of the restricted Schur polynomials. The recursion relations can be solved exactly in terms of symmetric Kravchuk polynomials or in terms of Clebsch-Gordan coefficients. This proves that the dilatation operator reduces to a decoupled set of harmonic oscillators and therefore it is integrable.
Directory of Open Access Journals (Sweden)
Pim P. Valentijn
2013-03-01
Full Text Available Introduction: Primary care has a central role in integrating care within a health system. However, conceptual ambiguity regarding integrated care hampers a systematic understanding. This paper proposes a conceptual framework that combines the concepts of primary care and integrated care, in order to understand the complexity of integrated care.Methods: The search method involved a combination of electronic database searches, hand searches of reference lists (snowball method and contacting researchers in the field. The process of synthesizing the literature was iterative, to relate the concepts of primary care and integrated care. First, we identified the general principles of primary care and integrated care. Second, we connected the dimensions of integrated care and the principles of primary care. Finally, to improve content validity we held several meetings with researchers in the field to develop and refine our conceptual framework.Results: The conceptual framework combines the functions of primary care with the dimensions of integrated care. Person-focused and population-based care serve as guiding principles for achieving integration across the care continuum. Integration plays complementary roles on the micro (clinical integration, meso (professional and organisational integration and macro (system integration level. Functional and normative integration ensure connectivity between the levels.Discussion: The presented conceptual framework is a first step to achieve a better understanding of the inter-relationships among the dimensions of integrated care from a primary care perspective.
Pentaho data integration beginner's guide
Roldán, María Carina
2013-01-01
This book focuses on teaching you by example. The book walks you through every aspect of Pentaho Data Integration, giving systematic instructions in a friendly style, allowing you to learn in front of your computer, playing with the tool. The extensive use of drawings and screenshots make the process of learning Pentaho Data Integration easy. Throughout the book, numerous tips and helpful hints are provided that you will not find anywhere else.This book is a must-have for software developers, database administrators, IT students, and everyone involved or interested in developing ETL solutions,
Integrating the healthcare supply chain.
Brennan, C D
1998-01-01
Today's integrated delivery systems (IDSs) require efficient supply chain processes to speed products to users at the lowest possible cost. Most excess costs within the supply chain are a result of inefficient and redundant processes involved in the transport and delivery of supplies from suppliers to healthcare providers. By integrating and assuming control of these supply chain processes, improving supply chain management practices, and organizing and implementing a disciplined redesign plan, IDSs can achieve substantial savings and better focus their organizations on their core patient care mission.
Measuring resilience in integrated planning
DEFF Research Database (Denmark)
Apneseth, K.; Wahl, A. M.; Hollnagel, E.
2013-01-01
This chapter demonstrates how a Resilience Analysis Grid (RAG) can be used to profile the performance of a company in terms of the four abilities that characterize a resilient organization. It describes the development of a new, RAG-based tool founded on Resilience Engineering principles that can...... be used to assess an organization's resilience. The tool was tested in a case study involving a company in the offshore oil and gas industry. The company had decided to adopt an Integrated Operations (IO) approach to operations and maintenance planning and the tool was used to evaluate the impact...... of the Integrated Planning (IPL) process on its resilience....
Measuring resilience in integrated planning
DEFF Research Database (Denmark)
Apneseth, K.; Wahl, A. M.; Hollnagel, E.
2013-01-01
This chapter demonstrates how a Resilience Analysis Grid (RAG) can be used to profile the performance of a company in terms of the four abilities that characterize a resilient organization. It describes the development of a new, RAG-based tool founded on Resilience Engineering principles that can...... be used to assess an organization's resilience. The tool was tested in a case study involving a company in the offshore oil and gas industry. The company had decided to adopt an Integrated Operations (IO) approach to operations and maintenance planning and the tool was used to evaluate the impact...... of the Integrated Planning (IPL) process on its resilience....
Parental Involvement in Norwegian Schools
Paulsen, Jan Merok
2012-01-01
This article examines findings on key challenges of school-parent relations in Norway. The review is based on recent large-scale studies on several issues, including formalized school-parent cooperation, parental involvement in the pedagogical discourse, and teacher perspectives on the parents' role in the school community. Findings suggest a…
Parent Involvement as Ritualized Practice
Doucet, Fabienne
2011-01-01
This article examines parent involvement (PI) as a ritual system using Turner's concept of root paradigms. Through a twofold analysis, I argue that the highly ritualized nature of PI practices creates a group identity among mainstream parents and schools that marginalizes diverse families. First, I point out three root paradigms in the ritual…
Putaminal involvement in Rasmussen encephalitis
Energy Technology Data Exchange (ETDEWEB)
Rajesh, Bhagavatheeswaran; Ashalatha, Radhakrishnan [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Department of Neurology, Trivandrum, Kerala (India); Kesavadas, Chandrasekharan; Thomas, Bejoy [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Department of Imaging Sciences and Interventional Radiology, Trivandrum, Kerala (India)
2006-08-15
Rasmussen encephalitis (RE) is a rare devastating disease of childhood causing progressive neurological deficits and intractable seizures, typically affecting one hemisphere. Characteristic MRI features include progressive unihemispheric focal cortical atrophy and grey- or white-matter high-signal changes and basal ganglion involvement, particularly of the caudate nucleus. To analyse the pattern of involvement of different brain structures in a series of patients with RE and to attempt clinical correlation. We reviewed the medical records and neuroimaging data of 12 patients diagnosed with RE satisfying the European Consensus Statement diagnostic criteria. The disease manifested as seizures in all patients and was refractory; epilepsia partialis continua was a notable feature (nine patients). Hemiparesis of varying grades was noted in all but one patient; none had extrapyramidal signs. Neuroimaging showed cortical involvement in the insular/periinsular regions in 11 patients. Caudate atrophy was noted in ten patients. Putaminal atrophy was seen in nine patients, six of whom had additional hyperintense signal changes. Our study highlights frequent putaminal atrophy and signal changes in RE, which suggests a more extensive basal ganglion involvement than emphasized previously. Recognition of putaminal changes may be a useful additional tool in the radiological diagnosis of RE. (orig.)
Neuronal involvement in cisplatin neuropathy
DEFF Research Database (Denmark)
Krarup-Hansen, A; Helweg-Larsen, Susanne Elisabeth; Schmalbruch, H
2007-01-01
Although it is well known that cisplatin causes a sensory neuropathy, the primary site of involvement is not established. The clinical symptoms localized in a stocking-glove distribution may be explained by a length dependent neuronopathy or by a distal axonopathy. To study whether the whole neur...
Promoting Active Involvement in Classrooms
Conderman, Greg; Bresnahan, Val; Hedin, Laura
2012-01-01
This article presents a rationale for using active involvement techniques, describes large- and small-group methods based on their documented effectiveness and applicability to K-12 classrooms, and illustrates their use. These approaches include ways of engaging students in large groups (e.g., unison responses, response cards, dry-erase boards,…
Involving Employees in Strategy innovation
DEFF Research Database (Denmark)
Friis, Ole Uhrskov; Koch, Christian
2011-01-01
Strategy as a practice and continuous innovation approaches are combined to conceptualise dilemmas of short versus long term and to analyse a case of employee participation as a particular example of strategy innovation. The case is a medium size textile company developing its strategy involving...
Managing Parent Involvement during Crisis
Merriman, Lynette S.
2008-01-01
In the wake of 9/11, Hurricane Katrina, and the Virginia Tech shooting tragedy, it is no surprise that concern for students' safety is the primary reason attributed to parents' increased involvement. Parents and university administrators share in their commitment to student safety. However, college and university staff who assume responsibility…
Acquisition Integration Models: How Large Companies Successfully Integrate Startups
Directory of Open Access Journals (Sweden)
Peter Carbone
2011-10-01
Full Text Available Mergers and acquisitions (M&A have been popular means for many companies to address the increasing pace and level of competition that they face. Large companies have pursued acquisitions to more quickly access technology, markets, and customers, and this approach has always been a viable exit strategy for startups. However, not all deals deliver the anticipated benefits, in large part due to poor integration of the acquired assets into the acquiring company. Integration can greatly impact the success of the acquisition and, indeed, the combined company’s overall market success. In this article, I explore the implementation of several integration models that have been put into place by a large company and extract principles that may assist negotiating parties with maximizing success. This perspective may also be of interest to smaller companies as they explore exit options while trying to ensure continued market success after acquisition. I assert that business success with acquisitions is dependent on an appropriate integration model, but that asset integration is not formulaic. Any integration effort must consider the specific market context and personnel involved.
Khachatryan, Vardan; Tumasyan, Armen; Adam, Wolfgang; Bergauer, Thomas; Dragicevic, Marko; Erö, Janos; Friedl, Markus; Fruehwirth, Rudolf; Ghete, Vasile Mihai; Hartl, Christian; Hörmann, Natascha; Hrubec, Josef; Jeitler, Manfred; Kiesenhofer, Wolfgang; Knünz, Valentin; Krammer, Manfred; Krätschmer, Ilse; Liko, Dietrich; Mikulec, Ivan; Rabady, Dinyar; Rahbaran, Babak; Rohringer, Herbert; Schöfbeck, Robert; Strauss, Josef; Treberer-Treberspurg, Wolfgang; Waltenberger, Wolfgang; Wulz, Claudia-Elisabeth; Mossolov, Vladimir; Shumeiko, Nikolai; Suarez Gonzalez, Juan; Alderweireldt, Sara; Bansal, Monika; Bansal, Sunil; Cornelis, Tom; De Wolf, Eddi A; Janssen, Xavier; Knutsson, Albert; Lauwers, Jasper; Luyckx, Sten; Ochesanu, Silvia; Rougny, Romain; Van De Klundert, Merijn; Van Haevermaet, Hans; Van Mechelen, Pierre; Van Remortel, Nick; Van Spilbeeck, Alex; Blekman, Freya; Blyweert, Stijn; D'Hondt, Jorgen; Daci, Nadir; Heracleous, Natalie; Keaveney, James; Lowette, Steven; Maes, Michael; Olbrechts, Annik; Python, Quentin; Strom, Derek; Tavernier, Stefaan; Van Doninck, Walter; Van Mulders, Petra; Van Onsem, Gerrit Patrick; Villella, Ilaria; Caillol, Cécile; Clerbaux, Barbara; De Lentdecker, Gilles; Dobur, Didar; Favart, Laurent; Gay, Arnaud; Grebenyuk, Anastasia; Léonard, Alexandre; Mohammadi, Abdollah; Perniè, Luca; Randle-conde, Aidan; Reis, Thomas; Seva, Tomislav; Thomas, Laurent; Vander Velde, Catherine; Vanlaer, Pascal; Wang, Jian; Zenoni, Florian; Adler, Volker; Beernaert, Kelly; Benucci, Leonardo; Cimmino, Anna; Costantini, Silvia; Crucy, Shannon; Dildick, Sven; Fagot, Alexis; Garcia, Guillaume; Mccartin, Joseph; Ocampo Rios, Alberto Andres; Ryckbosch, Dirk; Salva Diblen, Sinem; Sigamani, Michael; Strobbe, Nadja; Thyssen, Filip; Tytgat, Michael; Yazgan, Efe; Zaganidis, Nicolas; Basegmez, Suzan; Beluffi, Camille; Bruno, Giacomo; Castello, Roberto; Caudron, Adrien; Ceard, Ludivine; Da Silveira, Gustavo Gil; Delaere, Christophe; Du Pree, Tristan; Favart, Denis; Forthomme, Laurent; Giammanco, Andrea; Hollar, Jonathan; Jafari, Abideh; Jez, Pavel; Komm, Matthias; Lemaitre, Vincent; Nuttens, Claude; Pagano, Davide; Perrini, Lucia; Pin, Arnaud; Piotrzkowski, Krzysztof; Popov, Andrey; Quertenmont, Loic; Selvaggi, Michele; Vidal Marono, Miguel; Vizan Garcia, Jesus Manuel; Beliy, Nikita; Caebergs, Thierry; Daubie, Evelyne; Hammad, Gregory Habib; Aldá Júnior, Walter Luiz; Alves, Gilvan; Brito, Lucas; Correa Martins Junior, Marcos; Dos Reis Martins, Thiago; Mora Herrera, Clemencia; Pol, Maria Elena; Rebello Teles, Patricia; Carvalho, Wagner; Chinellato, Jose; Custódio, Analu; Melo Da Costa, Eliza; De Jesus Damiao, Dilson; De Oliveira Martins, Carley; Fonseca De Souza, Sandro; Malbouisson, Helena; Matos Figueiredo, Diego; Mundim, Luiz; Nogima, Helio; Prado Da Silva, Wanda Lucia; Santaolalla, Javier; Santoro, Alberto; Sznajder, Andre; Tonelli Manganote, Edmilson José; Vilela Pereira, Antonio; Bernardes, Cesar Augusto; Dogra, Sunil; Tomei, Thiago; De Moraes Gregores, Eduardo; Mercadante, Pedro G; Novaes, Sergio F; Padula, Sandra; Aleksandrov, Aleksandar; Genchev, Vladimir; Hadjiiska, Roumyana; Iaydjiev, Plamen; Marinov, Andrey; Piperov, Stefan; Rodozov, Mircho; Sultanov, Georgi; Vutova, Mariana; Dimitrov, Anton; Glushkov, Ivan; Litov, Leander; Pavlov, Borislav; Petkov, Peicho; Bian, Jian-Guo; Chen, Guo-Ming; Chen, He-Sheng; Chen, Mingshui; Cheng, Tongguang; Du, Ran; Jiang, Chun-Hua; Plestina, Roko; Romeo, Francesco; Tao, Junquan; Wang, Zheng; Asawatangtrakuldee, Chayanit; Ban, Yong; Li, Qiang; Liu, Shuai; Mao, Yajun; Qian, Si-Jin; Wang, Dayong; Zou, Wei; Avila, Carlos; Cabrera, Andrés; Chaparro Sierra, Luisa Fernanda; Florez, Carlos; Gomez, Juan Pablo; Gomez Moreno, Bernardo; Sanabria, Juan Carlos; Godinovic, Nikola; Lelas, Damir; Polic, Dunja; Puljak, Ivica; Antunovic, Zeljko; Kovac, Marko; Brigljevic, Vuko; Kadija, Kreso; Luetic, Jelena; Mekterovic, Darko; Sudic, Lucija; Attikis, Alexandros; Mavromanolakis, Georgios; Mousa, Jehad; Nicolaou, Charalambos; Ptochos, Fotios; Razis, Panos A; Bodlak, Martin; Finger, Miroslav; Finger Jr, Michael; Assran, Yasser; Elgammal, Sherif; Mahmoud, Mohammed; Radi, Amr; Kadastik, Mario; Murumaa, Marion; Raidal, Martti; Tiko, Andres; Eerola, Paula; Fedi, Giacomo; Voutilainen, Mikko; Härkönen, Jaakko; Karimäki, Veikko; Kinnunen, Ritva; Kortelainen, Matti J; Lampén, Tapio; Lassila-Perini, Kati; Lehti, Sami; Lindén, Tomas; Luukka, Panja-Riina; Mäenpää, Teppo; Peltola, Timo; Tuominen, Eija; Tuominiemi, Jorma; Tuovinen, Esa; Wendland, Lauri; Talvitie, Joonas; Tuuva, Tuure; Besancon, Marc; Couderc, Fabrice; Dejardin, Marc; Denegri, Daniel; Fabbro, Bernard; Faure, Jean-Louis; Favaro, Carlotta; Ferri, Federico; Ganjour, Serguei; Givernaud, Alain; Gras, Philippe; Hamel de Monchenault, Gautier; Jarry, Patrick; Locci, Elizabeth; Malcles, Julie; Rander, John; Rosowsky, André; Titov, Maksym; Baffioni, Stephanie; Beaudette, Florian; Busson, Philippe; Charlot, Claude; Dahms, Torsten; Dalchenko, Mykhailo; Dobrzynski, Ludwik; Filipovic, Nicolas; Florent, Alice; Granier de Cassagnac, Raphael; Mastrolorenzo, Luca; Miné, Philippe; Mironov, Camelia; Naranjo, Ivo Nicolas; Nguyen, Matthew; Ochando, Christophe; Paganini, Pascal; Regnard, Simon; Salerno, Roberto; Sauvan, Jean-Baptiste; Sirois, Yves; Veelken, Christian; Yilmaz, Yetkin; Zabi, Alexandre; Agram, Jean-Laurent; Andrea, Jeremy; Aubin, Alexandre; Bloch, Daniel; Brom, Jean-Marie; Chabert, Eric Christian; Collard, Caroline; Conte, Eric; Fontaine, Jean-Charles; Gelé, Denis; Goerlach, Ulrich; Goetzmann, Christophe; Le Bihan, Anne-Catherine; Skovpen, Kirill; Van Hove, Pierre; Gadrat, Sébastien; Beauceron, Stephanie; Beaupere, Nicolas; Boudoul, Gaelle; Bouvier, Elvire; Brochet, Sébastien; Carrillo Montoya, Camilo Andres; Chasserat, Julien; Chierici, Roberto; Contardo, Didier; Depasse, Pierre; El Mamouni, Houmani; Fan, Jiawei; Fay, Jean; Gascon, Susan; Gouzevitch, Maxime; Ille, Bernard; Kurca, Tibor; Lethuillier, Morgan; Mirabito, Laurent; Perries, Stephane; Ruiz Alvarez, José David; Sabes, David; Sgandurra, Louis; Sordini, Viola; Vander Donckt, Muriel; Verdier, Patrice; Viret, Sébastien; Xiao, Hong; Tsamalaidze, Zviad; Autermann, Christian; Beranek, Sarah; Bontenackels, Michael; Edelhoff, Matthias; Feld, Lutz; Heister, Arno; Hindrichs, Otto; Klein, Katja; Ostapchuk, Andrey; Raupach, Frank; Sammet, Jan; Schael, Stefan; Weber, Hendrik; Wittmer, Bruno; Zhukov, Valery; Ata, Metin; Brodski, Michael; Dietz-Laursonn, Erik; Duchardt, Deborah; Erdmann, Martin; Fischer, Robert; Güth, Andreas; Hebbeker, Thomas; Heidemann, Carsten; Hoepfner, Kerstin; Klingebiel, Dennis; Knutzen, Simon; Kreuzer, Peter; Merschmeyer, Markus; Meyer, Arnd; Millet, Philipp; Olschewski, Mark; Padeken, Klaas; Papacz, Paul; Reithler, Hans; Schmitz, Stefan Antonius; Sonnenschein, Lars; Teyssier, Daniel; Thüer, Sebastian; Weber, Martin; Cherepanov, Vladimir; Erdogan, Yusuf; Flügge, Günter; Geenen, Heiko; Geisler, Matthias; Haj Ahmad, Wael; Hoehle, Felix; Kargoll, Bastian; Kress, Thomas; Kuessel, Yvonne; Künsken, Andreas; Lingemann, Joschka; Nowack, Andreas; Nugent, Ian Michael; Perchalla, Lars; Pooth, Oliver; Stahl, Achim; Aldaya Martin, Maria; Asin, Ivan; Bartosik, Nazar; Behr, Joerg; Behrens, Ulf; Bell, Alan James; Bethani, Agni; Borras, Kerstin; Burgmeier, Armin; Cakir, Altan; Calligaris, Luigi; Campbell, Alan; Choudhury, Somnath; Costanza, Francesco; Diez Pardos, Carmen; Dolinska, Ganna; Dooling, Samantha; Dorland, Tyler; Eckerlin, Guenter; Eckstein, Doris; Eichhorn, Thomas; Flucke, Gero; Garay Garcia, Jasone; Geiser, Achim; Gunnellini, Paolo; Hauk, Johannes; Hempel, Maria; Jung, Hannes; Kalogeropoulos, Alexis; Kasemann, Matthias; Katsas, Panagiotis; Kieseler, Jan; Kleinwort, Claus; Korol, Ievgen; Krücker, Dirk; Lange, Wolfgang; Leonard, Jessica; Lipka, Katerina; Lobanov, Artur; Lohmann, Wolfgang; Lutz, Benjamin; Mankel, Rainer; Marfin, Ihar; Melzer-Pellmann, Isabell-Alissandra; Meyer, Andreas Bernhard; Mittag, Gregor; Mnich, Joachim; Mussgiller, Andreas; Naumann-Emme, Sebastian; Nayak, Aruna; Ntomari, Eleni; Perrey, Hanno; Pitzl, Daniel; Placakyte, Ringaile; Raspereza, Alexei; Ribeiro Cipriano, Pedro M; Roland, Benoit; Ron, Elias; Sahin, Mehmet Özgür; Salfeld-Nebgen, Jakob; Saxena, Pooja; Schoerner-Sadenius, Thomas; Schröder, Matthias; Seitz, Claudia; Spannagel, Simon; Vargas Trevino, Andrea Del Rocio; Walsh, Roberval; Wissing, Christoph; Blobel, Volker; Centis Vignali, Matteo; Draeger, Arne-Rasmus; Erfle, Joachim; Garutti, Erika; Goebel, Kristin; Görner, Martin; Haller, Johannes; Hoffmann, Malte; Höing, Rebekka Sophie; Junkes, Alexandra; Kirschenmann, Henning; Klanner, Robert; Kogler, Roman; Lange, Jörn; Lapsien, Tobias; Lenz, Teresa; Marchesini, Ivan; Ott, Jochen; Peiffer, Thomas; Perieanu, Adrian; Pietsch, Niklas; Poehlsen, Jennifer; Pöhlsen, Thomas; Rathjens, Denis; Sander, Christian; Schettler, Hannes; Schleper, Peter; Schlieckau, Eike; Schmidt, Alexander; Seidel, Markus; Sola, Valentina; Stadie, Hartmut; Steinbrück, Georg; Troendle, Daniel; Usai, Emanuele; Vanelderen, Lukas; Vanhoefer, Annika; Barth, Christian; Baus, Colin; Berger, Joram; Böser, Christian; Butz, Erik; Chwalek, Thorsten; De Boer, Wim; Descroix, Alexis; Dierlamm, Alexander; Feindt, Michael; Frensch, Felix; Giffels, Manuel; Gilbert, Andrew; Hartmann, Frank; Hauth, Thomas; Husemann, Ulrich; Katkov, Igor; Kornmayer, Andreas; Kuznetsova, Ekaterina; Lobelle Pardo, Patricia; Mozer, Matthias Ulrich; Müller, Thomas; Müller, Thomas; Nürnberg, Andreas; Quast, Gunter; Rabbertz, Klaus; Röcker, Steffen; Simonis, Hans-Jürgen; Stober, Fred-Markus Helmut; Ulrich, Ralf; Wagner-Kuhr, Jeannine; Wayand, Stefan; Weiler, Thomas; Wolf, Roger; Anagnostou, Georgios; Daskalakis, Georgios; Geralis, Theodoros; Giakoumopoulou, Viktoria Athina; Kyriakis, Aristotelis; Loukas, Demetrios; Markou, Athanasios; Markou, Christos; Psallidas, Andreas; Topsis-Giotis, Iasonas; Agapitos, Antonis; Kesisoglou, Stilianos; Panagiotou, Apostolos; Saoulidou, Niki; Stiliaris, Efstathios; Aslanoglou, Xenofon; Evangelou, Ioannis; Flouris, Giannis; Foudas, Costas; Kokkas, Panagiotis; Manthos, Nikolaos; Papadopoulos, Ioannis; Paradas, Evangelos; Strologas, John; Bencze, Gyorgy; Hajdu, Csaba; Hidas, Pàl; Horvath, Dezso; Sikler, Ferenc; Veszpremi, Viktor; Vesztergombi, Gyorgy; Zsigmond, Anna Julia; Beni, Noemi; Czellar, Sandor; Karancsi, János; Molnar, Jozsef; Palinkas, Jozsef; Szillasi, Zoltan; Makovec, Alajos; Raics, Peter; Trocsanyi, Zoltan Laszlo; Ujvari, Balazs; Swain, Sanjay Kumar; Beri, Suman Bala; Bhatnagar, Vipin; Gupta, Ruchi; Bhawandeep, Bhawandeep; Kalsi, Amandeep Kaur; Kaur, Manjit; Kumar, Ramandeep; Mittal, Monika; Nishu, Nishu; Singh, Jasbir; Kumar, Ashok; Kumar, Arun; Ahuja, Sudha; Bhardwaj, Ashutosh; Choudhary, Brajesh C; Kumar, Ajay; Malhotra, Shivali; Naimuddin, Md; Ranjan, Kirti; Sharma, Varun; Banerjee, Sunanda; Bhattacharya, Satyaki; Chatterjee, Kalyanmoy; Dutta, Suchandra; Gomber, Bhawna; Jain, Sandhya; Jain, Shilpi; Khurana, Raman; Modak, Atanu; Mukherjee, Swagata; Roy, Debarati; Sarkar, Subir; Sharan, Manoj; Abdulsalam, Abdulla; Dutta, Dipanwita; Kailas, Swaminathan; Kumar, Vineet; Mohanty, Ajit Kumar; Pant, Lalit Mohan; Shukla, Prashant; Topkar, Anita; Aziz, Tariq; Banerjee, Sudeshna; Bhowmik, Sandeep; Chatterjee, Rajdeep Mohan; Dewanjee, Ram Krishna; Dugad, Shashikant; Ganguly, Sanmay; Ghosh, Saranya; Guchait, Monoranjan; Gurtu, Atul; Kole, Gouranga; Kumar, Sanjeev; Maity, Manas; Majumder, Gobinda; Mazumdar, Kajari; Mohanty, Gagan Bihari; Parida, Bibhuti; Sudhakar, Katta; Wickramage, Nadeesha; Bakhshiansohi, Hamed; Behnamian, Hadi; Etesami, Seyed Mohsen; Fahim, Ali; Goldouzian, Reza; Khakzad, Mohsen; Mohammadi Najafabadi, Mojtaba; Naseri, Mohsen; Paktinat Mehdiabadi, Saeid; Rezaei Hosseinabadi, Ferdos; Safarzadeh, Batool; Zeinali, Maryam; Felcini, Marta; Grunewald, Martin; Abbrescia, Marcello; Calabria, Cesare; Chhibra, Simranjit Singh; Colaleo, Anna; Creanza, Donato; De Filippis, Nicola; De Palma, Mauro; Fiore, Luigi; Iaselli, Giuseppe; Maggi, Giorgio; Maggi, Marcello; My, Salvatore; Nuzzo, Salvatore; Pompili, Alexis; Pugliese, Gabriella; Radogna, Raffaella; Selvaggi, Giovanna; Sharma, Archana; Silvestris, Lucia; Venditti, Rosamaria; Verwilligen, Piet; Abbiendi, Giovanni; Benvenuti, Alberto; Bonacorsi, Daniele; Braibant-Giacomelli, Sylvie; Brigliadori, Luca; Campanini, Renato; Capiluppi, Paolo; Castro, Andrea; Cavallo, Francesca Romana; Codispoti, Giuseppe; Cuffiani, Marco; Dallavalle, Gaetano-Marco; Fabbri, Fabrizio; Fanfani, Alessandra; Fasanella, Daniele; Giacomelli, Paolo; Grandi, Claudio; Guiducci, Luigi; Marcellini, Stefano; Masetti, Gianni; Montanari, Alessandro; Navarria, Francesco; Perrotta, Andrea; Primavera, Federica; Rossi, Antonio; Rovelli, Tiziano; Siroli, Gian Piero; Tosi, Nicolò; Travaglini, Riccardo; Albergo, Sebastiano; Cappello, Gigi; Chiorboli, Massimiliano; Costa, Salvatore; Giordano, Ferdinando; Potenza, Renato; Tricomi, Alessia; Tuve, Cristina; Barbagli, Giuseppe; Ciulli, Vitaliano; Civinini, Carlo; D'Alessandro, Raffaello; Focardi, Ettore; Gallo, Elisabetta; Gonzi, Sandro; Gori, Valentina; Lenzi, Piergiulio; Meschini, Marco; Paoletti, Simone; Sguazzoni, Giacomo; Tropiano, Antonio; Benussi, Luigi; Bianco, Stefano; Fabbri, Franco; Piccolo, Davide; Ferretti, Roberta; Ferro, Fabrizio; Lo Vetere, Maurizio; Robutti, Enrico; Tosi, Silvano; Dinardo, Mauro Emanuele; Fiorendi, Sara; Gennai, Simone; Gerosa, Raffaele; Ghezzi, Alessio; Govoni, Pietro; Lucchini, Marco Toliman; Malvezzi, Sandra; Manzoni, Riccardo Andrea; Martelli, Arabella; Marzocchi, Badder; Menasce, Dario; Moroni, Luigi; Paganoni, Marco; Pedrini, Daniele; Ragazzi, Stefano; Redaelli, Nicola; Tabarelli de Fatis, Tommaso; Buontempo, Salvatore; Cavallo, Nicola; Di Guida, Salvatore; Fabozzi, Francesco; Iorio, Alberto Orso Maria; Lista, Luca; Meola, Sabino; Merola, Mario; Paolucci, Pierluigi; Azzi, Patrizia; Bacchetta, Nicola; Biasotto, Massimo; Bisello, Dario; Branca, Antonio; Carlin, Roberto; Checchia, Paolo; Dall'Osso, Martino; Dorigo, Tommaso; Dosselli, Umberto; Fanzago, Federica; Galanti, Mario; Gasparini, Ugo; Giubilato, Piero; Gozzelino, Andrea; Lacaprara, Stefano; Margoni, Martino; Meneguzzo, Anna Teresa; Pazzini, Jacopo; Pozzobon, Nicola; Ronchese, Paolo; Simonetto, Franco; Torassa, Ezio; Tosi, Mia; Ventura, Sandro; Zotto, Pierluigi; Zucchetta, Alberto; Gabusi, Michele; Ratti, Sergio P; Re, Valerio; Riccardi, Cristina; Salvini, Paola; Vitulo, Paolo; Biasini, Maurizio; Bilei, Gian Mario; Ciangottini, Diego; Fanò, Livio; Lariccia, Paolo; Mantovani, Giancarlo; Menichelli, Mauro; Saha, Anirban; Santocchia, Attilio; Spiezia, Aniello; Androsov, Konstantin; Azzurri, Paolo; Bagliesi, Giuseppe; Bernardini, Jacopo; Boccali, Tommaso; Broccolo, Giuseppe; Castaldi, Rino; Ciocci, Maria Agnese; Dell'Orso, Roberto; Donato, Silvio; Fiori, Francesco; Foà, Lorenzo; Giassi, Alessandro; Grippo, Maria Teresa; Ligabue, Franco; Lomtadze, Teimuraz; Martini, Luca; Messineo, Alberto; Moon, Chang-Seong; Palla, Fabrizio; Rizzi, Andrea; Savoy-Navarro, Aurore; Serban, Alin Titus; Spagnolo, Paolo; Squillacioti, Paola; Tenchini, Roberto; Tonelli, Guido; Venturi, Andrea; Verdini, Piero Giorgio; Vernieri, Caterina; Barone, Luciano; Cavallari, Francesca; D'imperio, Giulia; Del Re, Daniele; Diemoz, Marcella; Jorda, Clara; Longo, Egidio; Margaroli, Fabrizio; Meridiani, Paolo; Micheli, Francesco; Nourbakhsh, Shervin; Organtini, Giovanni; Paramatti, Riccardo; Rahatlou, Shahram; Rovelli, Chiara; Santanastasio, Francesco; Soffi, Livia; Traczyk, Piotr; Amapane, Nicola; Arcidiacono, Roberta; Argiro, Stefano; Arneodo, Michele; Bellan, Riccardo; Biino, Cristina; Cartiglia, Nicolo; Casasso, Stefano; Costa, Marco; Degano, Alessandro; Demaria, Natale; Finco, Linda; Mariotti, Chiara; Maselli, Silvia; Migliore, Ernesto; Monaco, Vincenzo; Musich, Marco; Obertino, Maria Margherita; Ortona, Giacomo; Pacher, Luca; Pastrone, Nadia; Pelliccioni, Mario; Pinna Angioni, Gian Luca; Potenza, Alberto; Romero, Alessandra; Ruspa, Marta; Sacchi, Roberto; Solano, Ada; Staiano, Amedeo; Tamponi, Umberto; Belforte, Stefano; Candelise, Vieri; Casarsa, Massimo; Cossutti, Fabio; Della Ricca, Giuseppe; Gobbo, Benigno; La Licata, Chiara; Marone, Matteo; Schizzi, Andrea; Umer, Tomo; Zanetti, Anna; Chang, Sunghyun; Kropivnitskaya, Anna; Nam, Soon-Kwon; Kim, Dong Hee; Kim, Gui Nyun; Kim, Min Suk; Kong, Dae Jung; Lee, Sangeun; Oh, Young Do; Park, Hyangkyu; Sakharov, Alexandre; Son, Dong-Chul; Kim, Tae Jeong; Kim, Jae Yool; Song, Sanghyeon; Choi, Suyong; Gyun, Dooyeon; Hong, Byung-Sik; Jo, Mihee; Kim, Hyunchul; Kim, Yongsun; Lee, Byounghoon; Lee, Kyong Sei; Park, Sung Keun; Roh, Youn; Yoo, Hwi Dong; Choi, Minkyoo; Kim, Ji Hyun; Park, Inkyu; Ryu, Geonmo; Ryu, Min Sang; Choi, Young-Il; Choi, Young Kyu; Goh, Junghwan; Kim, Donghyun; Kwon, Eunhyang; Lee, Jongseok; Yu, Intae; Juodagalvis, Andrius; Komaragiri, Jyothsna Rani; Md Ali, Mohd Adli Bin; Casimiro Linares, Edgar; Castilla-Valdez, Heriberto; De La Cruz-Burelo, Eduard; Heredia-de La Cruz, Ivan; Hernandez-Almada, Alberto; Lopez-Fernandez, Ricardo; Sánchez Hernández, Alberto; Carrillo Moreno, Salvador; Vazquez Valencia, Fabiola; Pedraza, Isabel; Salazar Ibarguen, Humberto Antonio; Morelos Pineda, Antonio; Krofcheck, David; Butler, Philip H; Reucroft, Steve; Ahmad, Ashfaq; Ahmad, Muhammad; Hassan, Qamar; Hoorani, Hafeez R; Khan, Wajid Ali; Khurshid, Taimoor; Shoaib, Muhammad; Bialkowska, Helena; Bluj, Michal; Boimska, Bożena; Frueboes, Tomasz; Górski, Maciej; Kazana, Malgorzata; Nawrocki, Krzysztof; Romanowska-Rybinska, Katarzyna; Szleper, Michal; Zalewski, Piotr; Brona, Grzegorz; Bunkowski, Karol; Cwiok, Mikolaj; Dominik, Wojciech; Doroba, Krzysztof; Kalinowski, Artur; Konecki, Marcin; Krolikowski, Jan; Misiura, Maciej; Olszewski, Michał; Wolszczak, Weronika; Bargassa, Pedrame; Beirão Da Cruz E Silva, Cristóvão; Faccioli, Pietro; Ferreira Parracho, Pedro Guilherme; Gallinaro, Michele; Lloret Iglesias, Lara; Nguyen, Federico; Rodrigues Antunes, Joao; Seixas, Joao; Varela, Joao; Vischia, Pietro; Golutvin, Igor; Gorbunov, Ilya; Kamenev, Alexey; Karjavin, Vladimir; Konoplyanikov, Viktor; Kozlov, Guennady; Lanev, Alexander; Malakhov, Alexander; Matveev, Viktor; Moisenz, Petr; Palichik, Vladimir; Perelygin, Victor; Savina, Maria; Shmatov, Sergey; Shulha, Siarhei; Skatchkov, Nikolai; Smirnov, Vitaly; Zarubin, Anatoli; Golovtsov, Victor; Ivanov, Yury; Kim, Victor; Levchenko, Petr; Murzin, Victor; Oreshkin, Vadim; Smirnov, Igor; Sulimov, Valentin; Uvarov, Lev; Vavilov, Sergey; Vorobyev, Alexey; Vorobyev, Andrey; Andreev, Yuri; Dermenev, Alexander; Gninenko, Sergei; Golubev, Nikolai; Kirsanov, Mikhail; Krasnikov, Nikolai; Pashenkov, Anatoli; Tlisov, Danila; Toropin, Alexander; Epshteyn, Vladimir; Gavrilov, Vladimir; Lychkovskaya, Natalia; Popov, Vladimir; Pozdnyakov, Ivan; Safronov, Grigory; Semenov, Sergey; Spiridonov, Alexander; Stolin, Viatcheslav; Vlasov, Evgueni; Zhokin, Alexander; Andreev, Vladimir; Azarkin, Maksim; Dremin, Igor; Kirakosyan, Martin; Leonidov, Andrey; Mesyats, Gennady; Rusakov, Sergey V; Vinogradov, Alexey; Belyaev, Andrey; Boos, Edouard; Bunichev, Viacheslav; Dubinin, Mikhail; Dudko, Lev; Gribushin, Andrey; Klyukhin, Vyacheslav; Kodolova, Olga; Lokhtin, Igor; Obraztsov, Stepan; Perfilov, Maxim; Petrushanko, Sergey; Savrin, Viktor; Azhgirey, Igor; Bayshev, Igor; Bitioukov, Sergei; Kachanov, Vassili; Kalinin, Alexey; Konstantinov, Dmitri; Krychkine, Victor; Petrov, Vladimir; Ryutin, Roman; Sobol, Andrei; Tourtchanovitch, Leonid; Troshin, Sergey; Tyurin, Nikolay; Uzunian, Andrey; Volkov, Alexey; Adzic, Petar; Ekmedzic, Marko; Milosevic, Jovan; Rekovic, Vladimir; Alcaraz Maestre, Juan; Battilana, Carlo; Calvo, Enrique; Cerrada, Marcos; Chamizo Llatas, Maria; Colino, Nicanor; De La Cruz, Begona; Delgado Peris, Antonio; Domínguez Vázquez, Daniel; Escalante Del Valle, Alberto; Fernandez Bedoya, Cristina; Fernández Ramos, Juan Pablo; Flix, Jose; Fouz, Maria Cruz; Garcia-Abia, Pablo; Gonzalez Lopez, Oscar; Goy Lopez, Silvia; Hernandez, Jose M; Josa, Maria Isabel; Navarro De Martino, Eduardo; Pérez-Calero Yzquierdo, Antonio María; Puerta Pelayo, Jesus; Quintario Olmeda, Adrián; Redondo, Ignacio; Romero, Luciano; Senghi Soares, Mara; Albajar, Carmen; de Trocóniz, Jorge F; Missiroli, Marino; Moran, Dermot; Brun, Hugues; Cuevas, Javier; Fernandez Menendez, Javier; Folgueras, Santiago; Gonzalez Caballero, Isidro; Brochero Cifuentes, Javier Andres; Cabrillo, Iban Jose; Calderon, Alicia; Duarte Campderros, Jordi; Fernandez, Marcos; Gomez, Gervasio; Graziano, Alberto; Lopez Virto, Amparo; Marco, Jesus; Marco, Rafael; Martinez Rivero, Celso; Matorras, Francisco; Munoz Sanchez, Francisca Javiela; Piedra Gomez, Jonatan; Rodrigo, Teresa; Rodríguez-Marrero, Ana Yaiza; Ruiz-Jimeno, Alberto; Scodellaro, Luca; Vila, Ivan; Vilar Cortabitarte, Rocio; Abbaneo, Duccio; Auffray, Etiennette; Auzinger, Georg; Bachtis, Michail; Baillon, Paul; Ball, Austin; Barney, David; Benaglia, Andrea; Bendavid, Joshua; Benhabib, Lamia; Benitez, Jose F; Bernet, Colin; Bloch, Philippe; Bocci, Andrea; Bonato, Alessio; Bondu, Olivier; Botta, Cristina; Breuker, Horst; Camporesi, Tiziano; Cerminara, Gianluca; Colafranceschi, Stefano; D'Alfonso, Mariarosaria; D'Enterria, David; Dabrowski, Anne; David Tinoco Mendes, Andre; De Guio, Federico; De Roeck, Albert; De Visscher, Simon; Di Marco, Emanuele; Dobson, Marc; Dordevic, Milos; Dorney, Brian; Dupont-Sagorin, Niels; Elliott-Peisert, Anna; Eugster, Jürg; Franzoni, Giovanni; Funk, Wolfgang; Gigi, Dominique; Gill, Karl; Giordano, Domenico; Girone, Maria; Glege, Frank; Guida, Roberto; Gundacker, Stefan; Guthoff, Moritz; Hammer, Josef; Hansen, Magnus; Harris, Philip; Hegeman, Jeroen; Innocente, Vincenzo; Janot, Patrick; Kousouris, Konstantinos; Krajczar, Krisztian; Lecoq, Paul; Lourenco, Carlos; Magini, Nicolo; Malgeri, Luca; Mannelli, Marcello; Marrouche, Jad; Masetti, Lorenzo; Meijers, Frans; Mersi, Stefano; Meschi, Emilio; Moortgat, Filip; Morovic, Srecko; Mulders, Martijn; Orsini, Luciano; Pape, Luc; Perez, Emmanuelle; Perrozzi, Luca; Petrilli, Achille; Petrucciani, Giovanni; Pfeiffer, Andreas; Pimiä, Martti; Piparo, Danilo; Plagge, Michael; Racz, Attila; Rolandi, Gigi; Rovere, Marco; Sakulin, Hannes; Schäfer, Christoph; Schwick, Christoph; Sharma, Archana; Siegrist, Patrice; Silva, Pedro; Simon, Michal; Sphicas, Paraskevas; Spiga, Daniele; Steggemann, Jan; Stieger, Benjamin; Stoye, Markus; Takahashi, Yuta; Treille, Daniel; Tsirou, Andromachi; Veres, Gabor Istvan; Wardle, Nicholas; Wöhri, Hermine Katharina; Wollny, Heiner; Zeuner, Wolfram Dietrich; Bertl, Willi; Deiters, Konrad; Erdmann, Wolfram; Horisberger, Roland; Ingram, Quentin; Kaestli, Hans-Christian; Kotlinski, Danek; Langenegger, Urs; Renker, Dieter; Rohe, Tilman; Bachmair, Felix; Bäni, Lukas; Bianchini, Lorenzo; Buchmann, Marco-Andrea; Casal, Bruno; Chanon, Nicolas; Dissertori, Günther; Dittmar, Michael; Donegà, Mauro; Dünser, Marc; Eller, Philipp; Grab, Christoph; Hits, Dmitry; Hoss, Jan; Lustermann, Werner; Mangano, Boris; Marini, Andrea Carlo; Marionneau, Matthieu; Martinez Ruiz del Arbol, Pablo; Masciovecchio, Mario; Meister, Daniel; Mohr, Niklas; Musella, Pasquale; Nägeli, Christoph; Nessi-Tedaldi, Francesca; Pandolfi, Francesco; Pauss, Felicitas; Peruzzi, Marco; Quittnat, Milena; Rebane, Liis; Rossini, Marco; Starodumov, Andrei; Takahashi, Maiko; Theofilatos, Konstantinos; Wallny, Rainer; Weber, Hannsjoerg Artur; Amsler, Claude; Canelli, Maria Florencia; Chiochia, Vincenzo; De Cosa, Annapaola; Hinzmann, Andreas; Hreus, Tomas; Kilminster, Benjamin; Lange, Clemens; Millan Mejias, Barbara; Ngadiuba, Jennifer; Pinna, Deborah; Robmann, Peter; Ronga, Frederic Jean; Taroni, Silvia; Verzetti, Mauro; Yang, Yong; Cardaci, Marco; Chen, Kuan-Hsin; Ferro, Cristina; Kuo, Chia-Ming; Lin, Willis; Lu, Yun-Ju; Volpe, Roberta; Yu, Shin-Shan; Chang, Paoti; Chang, You-Hao; Chang, Yu-Wei; Chao, Yuan; Chen, Kai-Feng; Chen, Po-Hsun; Dietz, Charles; Grundler, Ulysses; Hou, George Wei-Shu; Kao, Kai-Yi; Liu, Yueh-Feng; Lu, Rong-Shyang; Majumder, Devdatta; Petrakou, Eleni; Tzeng, Yeng-Ming; Wilken, Rachel; Asavapibhop, Burin; Singh, Gurpreet; Srimanobhas, Norraphat; Suwonjandee, Narumon; Adiguzel, Aytul; Bakirci, Mustafa Numan; Cerci, Salim; Dozen, Candan; Dumanoglu, Isa; Eskut, Eda; Girgis, Semiray; Gokbulut, Gul; Gurpinar, Emine; Hos, Ilknur; Kangal, Evrim Ersin; Kayis Topaksu, Aysel; Onengut, Gulsen; Ozdemir, Kadri; Ozturk, Sertac; Polatoz, Ayse; Sunar Cerci, Deniz; Tali, Bayram; Topakli, Huseyin; Vergili, Mehmet; Akin, Ilina Vasileva; Bilin, Bugra; Bilmis, Selcuk; Gamsizkan, Halil; Isildak, Bora; Karapinar, Guler; Ocalan, Kadir; Sekmen, Sezen; Surat, Ugur Emrah; Yalvac, Metin; Zeyrek, Mehmet; Albayrak, Elif Asli; Gülmez, Erhan; Kaya, Mithat; Kaya, Ozlem; Yetkin, Taylan; Cankocak, Kerem; Vardarlı, Fuat Ilkehan; Levchuk, Leonid; Sorokin, Pavel; Brooke, James John; Clement, Emyr; Cussans, David; Flacher, Henning; Goldstein, Joel; Grimes, Mark; Heath, Greg P; Heath, Helen F; Jacob, Jeson; Kreczko, Lukasz; Lucas, Chris; Meng, Zhaoxia; Newbold, Dave M; Paramesvaran, Sudarshan; Poll, Anthony; Sakuma, Tai; Senkin, Sergey; Smith, Vincent J; Williams, Thomas; Bell, Ken W; Belyaev, Alexander; Brew, Christopher; Brown, Robert M; Cockerill, David JA; Coughlan, John A; Harder, Kristian; Harper, Sam; Olaiya, Emmanuel; Petyt, David; Shepherd-Themistocleous, Claire; Thea, Alessandro; Tomalin, Ian R; Womersley, William John; Worm, Steven; Baber, Mark; Bainbridge, Robert; Buchmuller, Oliver; Burton, Darren; Colling, David; Cripps, Nicholas; Dauncey, Paul; Davies, Gavin; Della Negra, Michel; Dunne, Patrick; Ferguson, William; Fulcher, Jonathan; Futyan, David; Hall, Geoffrey; Iles, Gregory; Jarvis, Martyn; Karapostoli, Georgia; Kenzie, Matthew; Lane, Rebecca; Lucas, Robyn; Lyons, Louis; Magnan, Anne-Marie; Malik, Sarah; Mathias, Bryn; Nash, Jordan; Nikitenko, Alexander; Pela, Joao; Pesaresi, Mark; Petridis, Konstantinos; Raymond, David Mark; Rogerson, Samuel; Rose, Andrew; Seez, Christopher; Sharp, Peter; Tapper, Alexander; Vazquez Acosta, Monica; Virdee, Tejinder; Zenz, Seth Conrad; Cole, Joanne; Hobson, Peter R; Khan, Akram; Kyberd, Paul; Leggat, Duncan; Leslie, Dawn; Reid, Ivan; Symonds, Philip; Teodorescu, Liliana; Turner, Mark; Dittmann, Jay; Hatakeyama, Kenichi; Kasmi, Azeddine; Liu, Hongxuan; Scarborough, Tara; Charaf, Otman; Cooper, Seth; Henderson, Conor; Rumerio, Paolo; Avetisyan, Aram; Bose, Tulika; Fantasia, Cory; Lawson, Philip; Richardson, Clint; Rohlf, James; St John, Jason; Sulak, Lawrence; Alimena, Juliette; Berry, Edmund; Bhattacharya, Saptaparna; Christopher, Grant; Cutts, David; Demiragli, Zeynep; Dhingra, Nitish; Ferapontov, Alexey; Garabedian, Alex; Heintz, Ulrich; Kukartsev, Gennadiy; Laird, Edward; Landsberg, Greg; Luk, Michael; Narain, Meenakshi; Segala, Michael; Sinthuprasith, Tutanon; Speer, Thomas; Swanson, Joshua; Breedon, Richard; Breto, Guillermo; Calderon De La Barca Sanchez, Manuel; Chauhan, Sushil; Chertok, Maxwell; Conway, John; Conway, Rylan; Cox, Peter Timothy; Erbacher, Robin; Gardner, Michael; Ko, Winston; Lander, Richard; Miceli, Tia; Mulhearn, Michael; Pellett, Dave; Pilot, Justin; Ricci-Tam, Francesca; Searle, Matthew; Shalhout, Shalhout; Smith, John; Squires, Michael; Stolp, Dustin; Tripathi, Mani; Wilbur, Scott; Yohay, Rachel; Cousins, Robert; Everaerts, Pieter; Farrell, Chris; Hauser, Jay; Ignatenko, Mikhail; Rakness, Gregory; Takasugi, Eric; Valuev, Vyacheslav; Weber, Matthias; Burt, Kira; Clare, Robert; Ellison, John Anthony; Gary, J William; Hanson, Gail; Heilman, Jesse; Ivova Rikova, Mirena; Jandir, Pawandeep; Kennedy, Elizabeth; Lacroix, Florent; Long, Owen Rosser; Luthra, Arun; Malberti, Martina; Olmedo Negrete, Manuel; Shrinivas, Amithabh; Sumowidagdo, Suharyo; Wimpenny, Stephen; Branson, James G; Cerati, Giuseppe Benedetto; Cittolin, Sergio; D'Agnolo, Raffaele Tito; Holzner, André; Kelley, Ryan; Klein, Daniel; Letts, James; Macneill, Ian; Olivito, Dominick; Padhi, Sanjay; Palmer, Christopher; Pieri, Marco; Sani, Matteo; Sharma, Vivek; Simon, Sean; Tadel, Matevz; Tu, Yanjun; Vartak, Adish; Welke, Charles; Würthwein, Frank; Yagil, Avraham; Barge, Derek; Bradmiller-Feld, John; Campagnari, Claudio; Danielson, Thomas; Dishaw, Adam; Dutta, Valentina; Flowers, Kristen; Franco Sevilla, Manuel; Geffert, Paul; George, Christopher; Golf, Frank; Gouskos, Loukas; Incandela, Joe; Justus, Christopher; Mccoll, Nickolas; Richman, Jeffrey; Stuart, David; To, Wing; West, Christopher; Yoo, Jaehyeok; Apresyan, Artur; Bornheim, Adolf; Bunn, Julian; Chen, Yi; Duarte, Javier; Mott, Alexander; Newman, Harvey B; Pena, Cristian; Pierini, Maurizio; Spiropulu, Maria; Vlimant, Jean-Roch; Wilkinson, Richard; Xie, Si; Zhu, Ren-Yuan; Azzolini, Virginia; Calamba, Aristotle; Carlson, Benjamin; Ferguson, Thomas; Iiyama, Yutaro; Paulini, Manfred; Russ, James; Vogel, Helmut; Vorobiev, Igor; Cumalat, John Perry; Ford, William T; Gaz, Alessandro; Krohn, Michael; Luiggi Lopez, Eduardo; Nauenberg, Uriel; Smith, James; Stenson, Kevin; Ulmer, Keith; Wagner, Stephen Robert; Alexander, James; Chatterjee, Avishek; Chaves, Jorge; Chu, Jennifer; Dittmer, Susan; Eggert, Nicholas; Mirman, Nathan; Nicolas Kaufman, Gala; Patterson, Juliet Ritchie; Ryd, Anders; Salvati, Emmanuele; Skinnari, Louise; Sun, Werner; Teo, Wee Don; Thom, Julia; Thompson, Joshua; Tucker, Jordan; Weng, Yao; Winstrom, Lucas; Wittich, Peter; Winn, Dave; Abdullin, Salavat; Albrow, Michael; Anderson, Jacob; Apollinari, Giorgio; Bauerdick, Lothar AT; Beretvas, Andrew; Berryhill, Jeffrey; Bhat, Pushpalatha C; Bolla, Gino; Burkett, Kevin; Butler, Joel Nathan; Cheung, Harry; Chlebana, Frank; Cihangir, Selcuk; Elvira, Victor Daniel; Fisk, Ian; Freeman, Jim; Gao, Yanyan; Gottschalk, Erik; Gray, Lindsey; Green, Dan; Grünendahl, Stefan; Gutsche, Oliver; Hanlon, Jim; Hare, Daryl; Harris, Robert M; Hirschauer, James; Hooberman, Benjamin; Jindariani, Sergo; Johnson, Marvin; Joshi, Umesh; Kaadze, Ketino; Klima, Boaz; Kreis, Benjamin; Kwan, Simon; Linacre, Jacob; Lincoln, Don; Lipton, Ron; Liu, Tiehui; Lykken, Joseph; Maeshima, Kaori; Marraffino, John Michael; Martinez Outschoorn, Verena Ingrid; Maruyama, Sho; Mason, David; McBride, Patricia; Merkel, Petra; Mishra, Kalanand; Mrenna, Stephen; Nahn, Steve; Newman-Holmes, Catherine; O'Dell, Vivian; Prokofyev, Oleg; Sexton-Kennedy, Elizabeth; Sharma, Seema; Soha, Aron; Spalding, William J; Spiegel, Leonard; Taylor, Lucas; Tkaczyk, Slawek; Tran, Nhan Viet; Uplegger, Lorenzo; Vaandering, Eric Wayne; Vidal, Richard; Whitbeck, Andrew; Whitmore, Juliana; Yang, Fan; Acosta, Darin; Avery, Paul; Bortignon, Pierluigi; Bourilkov, Dimitri; Carver, Matthew; Curry, David; Das, Souvik; De Gruttola, Michele; Di Giovanni, Gian Piero; Field, Richard D; Fisher, Matthew; Furic, Ivan-Kresimir; Hugon, Justin; Konigsberg, Jacobo; Korytov, Andrey; Kypreos, Theodore; Low, Jia Fu; Matchev, Konstantin; Mei, Hualin; Milenovic, Predrag; Mitselmakher, Guenakh; Muniz, Lana; Rinkevicius, Aurelijus; Shchutska, Lesya; Snowball, Matthew; Sperka, David; Yelton, John; Zakaria, Mohammed; Hewamanage, Samantha; Linn, Stephan; Markowitz, Pete; Martinez, German; Rodriguez, Jorge Luis; Adams, Todd; Askew, Andrew; Bochenek, Joseph; Diamond, Brendan; Haas, Jeff; Hagopian, Sharon; Hagopian, Vasken; Johnson, Kurtis F; Prosper, Harrison; Veeraraghavan, Venkatesh; Weinberg, Marc; Baarmand, Marc M; Hohlmann, Marcus; Kalakhety, Himali; Yumiceva, Francisco; Adams, Mark Raymond; Apanasevich, Leonard; Berry, Douglas; Betts, Russell Richard; Bucinskaite, Inga; Cavanaugh, Richard; Evdokimov, Olga; Gauthier, Lucie; Gerber, Cecilia Elena; Hofman, David Jonathan; Kurt, Pelin; Moon, Dong Ho; O'Brien, Christine; Sandoval Gonzalez, Irving Daniel; Silkworth, Christopher; Turner, Paul; Varelas, Nikos; Bilki, Burak; Clarida, Warren; Dilsiz, Kamuran; Haytmyradov, Maksat; Merlo, Jean-Pierre; Mermerkaya, Hamit; Mestvirishvili, Alexi; Moeller, Anthony; Nachtman, Jane; Ogul, Hasan; Onel, Yasar; Ozok, Ferhat; Penzo, Aldo; Rahmat, Rahmat; Sen, Sercan; Tan, Ping; Tiras, Emrah; Wetzel, James; Yi, Kai; Barnett, Bruce Arnold; Blumenfeld, Barry; Bolognesi, Sara; Fehling, David; Gritsan, Andrei; Maksimovic, Petar; Martin, Christopher; Swartz, Morris; Baringer, Philip; Bean, Alice; Benelli, Gabriele; Bruner, Christopher; Kenny III, Raymond Patrick; Malek, Magdalena; Murray, Michael; Noonan, Daniel; Sanders, Stephen; Sekaric, Jadranka; Stringer, Robert; Wang, Quan; Wood, Jeffrey Scott; Chakaberia, Irakli; Ivanov, Andrew; Khalil, Sadia; Makouski, Mikhail; Maravin, Yurii; Saini, Lovedeep Kaur; Skhirtladze, Nikoloz; Svintradze, Irakli; Gronberg, Jeffrey; Lange, David; Rebassoo, Finn; Wright, Douglas; Baden, Drew; Belloni, Alberto; Calvert, Brian; Eno, Sarah Catherine; Gomez, Jaime; Hadley, Nicholas John; Kellogg, Richard G; Kolberg, Ted; Lu, Ying; Mignerey, Alice; Pedro, Kevin; Skuja, Andris; Tonjes, Marguerite; Tonwar, Suresh C; Apyan, Aram; Barbieri, Richard; Bauer, Gerry; Busza, Wit; Cali, Ivan Amos; Chan, Matthew; Di Matteo, Leonardo; Gomez Ceballos, Guillelmo; Goncharov, Maxim; Gulhan, Doga; Klute, Markus; Lai, Yue Shi; Lee, Yen-Jie; Levin, Andrew; Luckey, Paul David; Ma, Teng; Paus, Christoph; Ralph, Duncan; Roland, Christof; Roland, Gunther; Stephans, George; Stöckli, Fabian; Sumorok, Konstanty; Velicanu, Dragos; Veverka, Jan; Wyslouch, Bolek; Yang, Mingming; Zanetti, Marco; Zhukova, Victoria; Dahmes, Bryan; Gude, Alexander; Kao, Shih-Chuan; Klapoetke, Kevin; Kubota, Yuichi; Mans, Jeremy; Pastika, Nathaniel; Rusack, Roger; Singovsky, Alexander; Tambe, Norbert; Turkewitz, Jared; Acosta, John Gabriel; Oliveros, Sandra; Avdeeva, Ekaterina; Bloom, Kenneth; Bose, Suvadeep; Claes, Daniel R; Dominguez, Aaron; Gonzalez Suarez, Rebeca; Keller, Jason; Knowlton, Dan; Kravchenko, Ilya; Lazo-Flores, Jose; Meier, Frank; Ratnikov, Fedor; Snow, Gregory R; Zvada, Marian; Dolen, James; Godshalk, Andrew; Iashvili, Ia; Kharchilava, Avto; Kumar, Ashish; Rappoccio, Salvatore; Alverson, George; Barberis, Emanuela; Baumgartel, Darin; Chasco, Matthew; Massironi, Andrea; Morse, David Michael; Nash, David; Orimoto, Toyoko; Trocino, Daniele; Wang, Ren-Jie; Wood, Darien; Zhang, Jinzhong; Hahn, Kristan Allan; Kubik, Andrew; Mucia, Nicholas; Odell, Nathaniel; Pollack, Brian; Pozdnyakov, Andrey; Schmitt, Michael Henry; Stoynev, Stoyan; Sung, Kevin; Velasco, Mayda; Won, Steven; Brinkerhoff, Andrew; Chan, Kwok Ming; Drozdetskiy, Alexey; Hildreth, Michael; Jessop, Colin; Karmgard, Daniel John; Kellams, Nathan; Lannon, Kevin; Lynch, Sean; Marinelli, Nancy; Musienko, Yuri; Pearson, Tessa; Planer, Michael; Ruchti, Randy; Smith, Geoffrey; Valls, Nil; Wayne, Mitchell; Wolf, Matthias; Woodard, Anna; Antonelli, Louis; Brinson, Jessica; Bylsma, Ben; Durkin, Lloyd Stanley; Flowers, Sean; Hart, Andrew; Hill, Christopher; Hughes, Richard; Kotov, Khristian; Ling, Ta-Yung; Luo, Wuming; Puigh, Darren; Rodenburg, Marissa; Winer, Brian L; Wolfe, Homer; Wulsin, Howard Wells; Driga, Olga; Elmer, Peter; Hardenbrook, Joshua; Hebda, Philip; Hunt, Adam; Koay, Sue Ann; Lujan, Paul; Marlow, Daniel; Medvedeva, Tatiana; Mooney, Michael; Olsen, James; Piroué, Pierre; Quan, Xiaohang; Saka, Halil; Stickland, David; Tully, Christopher; Werner, Jeremy Scott; Zuranski, Andrzej; Brownson, Eric; Malik, Sudhir; Mendez, Hector; Ramirez Vargas, Juan Eduardo; Barnes, Virgil E; Benedetti, Daniele; Bortoletto, Daniela; De Mattia, Marco; Gutay, Laszlo; Hu, Zhen; Jha, Manoj; Jones, Matthew; Jung, Kurt; Kress, Matthew; Leonardo, Nuno; Lopes Pegna, David; Maroussov, Vassili; Miller, David Harry; Neumeister, Norbert; Radburn-Smith, Benjamin Charles; Shi, Xin; Shipsey, Ian; Silvers, David; Svyatkovskiy, Alexey; Wang, Fuqiang; Xie, Wei; Xu, Lingshan; Zablocki, Jakub; Zheng, Yu; Parashar, Neeti; Stupak, John; Adair, Antony; Akgun, Bora; Ecklund, Karl Matthew; Geurts, Frank JM; Li, Wei; Michlin, Benjamin; Padley, Brian Paul; Redjimi, Radia; Roberts, Jay; Zabel, James; Betchart, Burton; Bodek, Arie; Covarelli, Roberto; de Barbaro, Pawel; Demina, Regina; Eshaq, Yossof; Ferbel, Thomas; Garcia-Bellido, Aran; Goldenzweig, Pablo; Han, Jiyeon; Harel, Amnon; Khukhunaishvili, Aleko; Korjenevski, Sergey; Petrillo, Gianluca; Vishnevskiy, Dmitry; Ciesielski, Robert; Demortier, Luc; Goulianos, Konstantin; Mesropian, Christina; Arora, Sanjay; Barker, Anthony; Chou, John Paul; Contreras-Campana, Christian; Contreras-Campana, Emmanuel; Duggan, Daniel; Ferencek, Dinko; Gershtein, Yuri; Gray, Richard; Halkiadakis, Eva; Hidas, Dean; Kaplan, Steven; Lath, Amitabh; Panwalkar, Shruti; Park, Michael; Patel, Rishi; Salur, Sevil; Schnetzer, Steve; Somalwar, Sunil; Stone, Robert; Thomas, Scott; Thomassen, Peter; Walker, Matthew; Rose, Keith; Spanier, Stefan; York, Andrew; Bouhali, Othmane; Castaneda Hernandez, Alfredo; Eusebi, Ricardo; Flanagan, Will; Gilmore, Jason; Kamon, Teruki; Khotilovich, Vadim; Krutelyov, Vyacheslav; Montalvo, Roy; Osipenkov, Ilya; Pakhotin, Yuriy; Perloff, Alexx; Roe, Jeffrey; Rose, Anthony; Safonov, Alexei; Suarez, Indara; Tatarinov, Aysen; Akchurin, Nural; Cowden, Christopher; Damgov, Jordan; Dragoiu, Cosmin; Dudero, Phillip Russell; Faulkner, James; Kovitanggoon, Kittikul; Kunori, Shuichi; Lee, Sung Won; Libeiro, Terence; Volobouev, Igor; Appelt, Eric; Delannoy, Andrés G; Greene, Senta; Gurrola, Alfredo; Johns, Willard; Maguire, Charles; Mao, Yaxian; Melo, Andrew; Sharma, Monika; Sheldon, Paul; Snook, Benjamin; Tuo, Shengquan; Velkovska, Julia; Arenton, Michael Wayne; Boutle, Sarah; Cox, Bradley; Francis, Brian; Goodell, Joseph; Hirosky, Robert; Ledovskoy, Alexander; Li, Hengne; Lin, Chuanzhe; Neu, Christopher; Wood, John; Clarke, Christopher; Harr, Robert; Karchin, Paul Edmund; Kottachchi Kankanamge Don, Chamath; Lamichhane, Pramod; Sturdy, Jared; Belknap, Donald; Carlsmith, Duncan; Cepeda, Maria; Dasu, Sridhara; Dodd, Laura; Duric, Senka; Friis, Evan; Hall-Wilton, Richard; Herndon, Matthew; Hervé, Alain; Klabbers, Pamela; Lanaro, Armando; Lazaridis, Christos; Levine, Aaron; Loveless, Richard; Mohapatra, Ajit; Ojalvo, Isabel; Perry, Thomas; Pierro, Giuseppe Antonio; Polese, Giovanni; Ross, Ian; Sarangi, Tapas; Savin, Alexander; Smith, Wesley H; Taylor, Devin; Vuosalo, Carl; Woods, Nathaniel
2015-03-18
A search is performed for long-lived particles that decay into final states that include a pair of electrons or a pair of muons. The experimental signature is a distinctive topology consisting of a pair of charge dleptons originating from a displaced secondary vertex. Events corresponding to an integrated luminosity of $19.6\\,(20.5)~\\mathrm{fb}^{-1}$ in the electron (muon) channel were collected with the CMS detector at the CERN LHC in proton-proton collisions at $\\sqrt{s} = 8~\\mathrm{TeV}$. No significant excess is observed above standard model expectations. Upper limits on the product of the cross section and branching fraction of such a signal are presented as a function of the long-lived particle's mean proper decay length. The limits are presented in an approximately model-independent way, allowing them to be applied to a wide class of models yielding the above topology. Over much of the investigated parameter space, the limits obtained are the most stringent to date. In the specific case of a model in w...
A Sociology of Knowledge Approach to European Integration
DEFF Research Database (Denmark)
Adler-Nissen, Rebecca; Kropp, Kristoffer
2015-01-01
Scholars are deeply involved in the process of European integration, but we lack systematic understanding of this involvement. On the one hand, scholars, academic ideas and ideologies shape European integration and policies (e.g. the Economic and Monetary Union and the free movement of people...
Audiovisual Integration in High Functioning Adults with Autism
Keane, Brian P.; Rosenthal, Orna; Chun, Nicole H.; Shams, Ladan
2010-01-01
Autism involves various perceptual benefits and deficits, but it is unclear if the disorder also involves anomalous audiovisual integration. To address this issue, we compared the performance of high-functioning adults with autism and matched controls on experiments investigating the audiovisual integration of speech, spatiotemporal relations, and…
Integrated Structural Design Education
DEFF Research Database (Denmark)
Bjerregaard Jensen, Lotte; Almegaard, Henrik
2011-01-01
In Environmental Impact Assessment (EIA), the environment is broadly defined and includes not only quantifiable aspects, but also social conditions, scenic beauty, traffic, cultural heritage, and commercial development. A successful bridge design must comply with all of these demands according to...... of a project, function well in design teams, and comply with EU EIA demands.......In Environmental Impact Assessment (EIA), the environment is broadly defined and includes not only quantifiable aspects, but also social conditions, scenic beauty, traffic, cultural heritage, and commercial development. A successful bridge design must comply with all of these demands according...... landscaping and structural design. The integrated courses create a setting for learning about the design of large-scale structures and involve geometry, statics, computer simulation, graphical design and landscape architecture. Together, they educate engineers who can take part in the early design phases...
Desktop Computing Integration Project
Tureman, Robert L., Jr.
1992-01-01
The Desktop Computing Integration Project for the Human Resources Management Division (HRMD) of LaRC was designed to help division personnel use personal computing resources to perform job tasks. The three goals of the project were to involve HRMD personnel in desktop computing, link mainframe data to desktop capabilities, and to estimate training needs for the division. The project resulted in increased usage of personal computers by Awards specialists, an increased awareness of LaRC resources to help perform tasks, and personal computer output that was used in presentation of information to center personnel. In addition, the necessary skills for HRMD personal computer users were identified. The Awards Office was chosen for the project because of the consistency of their data requests and the desire of employees in that area to use the personal computer.
Integrated astrophysical modeling
Energy Technology Data Exchange (ETDEWEB)
Weaver, T. A.; Eastman, R. G.; Dubois, P.; Eltgroth, P. G.; Gentile, N.; Jedamzik, K.; Wilson, J. R.
1997-06-03
In this project, we have developed prototype techniques for defining and extending a variety of astrophysical modeling capabilities, including those involving multidimensional hydrodynamics, complex transport, and flexibly-coupled equation-of state and nuclear reaction networks. As expected, this project is having both near-term payoffs in understanding complex astrophysical phenomena, as well as significant spin-offs in terms of people and ideas to related ASCI code efforts. Most of our work in the first part of this project was focused on the modularization, extension, and initial integration of 4 previously separate and incommensurate codes: the stellar evolution/explosion code KEPLER; the non-LTE spectral line transport code, EDDINGTON, used for modeling supernovae spectra; the 3-D smooth particle hydro code, PIP; and the discontinuous-finite-element, 3D hydro module from the lCF3D code.
Dehumanization: an integrative review.
Haslam, Nick
2006-01-01
The concept of dehumanization lacks a systematic theoretical basis, and research that addresses it has yet to be integrated. Manifestations and theories of dehumanization are reviewed, and a new model is developed. Two forms of dehumanization are proposed, involving the denial to others of 2 distinct senses of humanness: characteristics that are uniquely human and those that constitute human nature. Denying uniquely human attributes to others represents them as animal-like, and denying human nature to others represents them as objects or automata. Cognitive underpinnings of the "animalistic" and "mechanistic" forms of dehumanization are proposed. An expanded sense of dehumanization emerges, in which the phenomenon is not unitary, is not restricted to the intergroup context, and does not occur only under conditions of conflict or extreme negative evaluation. Instead, dehumanization becomes an everyday social phenomenon, rooted in ordinary social-cognitive processes.
Simplification of integrity constraints for data integration
DEFF Research Database (Denmark)
Christiansen, Henning; Martinenghi, Davide
2004-01-01
When two or more databases are combined into a global one, integrity may be violated even when each database is consistent with its own local integrity constraints. Efficient methods for checking global integrity in data integration systems are called for: answers to queries can then be trusted...... together with given a priori constraints on the combination, so that only a minimal number of tuples needs to be considered. Combination from scratch, integration of a new source, and absorption of local updates are dealt with for both the local-as-view and global-as-view approaches to data integration....
Design for Mass User Involvement
DEFF Research Database (Denmark)
Vianello, Giovanna; Tan, Adrian
as it creates a closer relationship to customers as well as creating the best possibilities for reducing impact of products on our natural environment. This new way of organizing the development process in collaboration with users holds many opportunities, but also challenges for companies and researchers. We...... be broadly adopted by the masses of people in the next century. Design methods are powerful tools to create solutions that fulfill the needs of people and improve their lives. Based on emerging trends in design and development as well as projecting current trends in the world today, we propose a new design...... formalism for the future in 2030 that is suited for a high tech, global manufacturing company. The design formalism involves the user throughout the design process and involves the company in the entire lifecycle of its products. It is believed that this approach will give companies a competitive advantage...
Inclusive Briefing and User Involvement
DEFF Research Database (Denmark)
Jensen, Per Anker
2011-01-01
includes a literature study on briefing and user involvement in building projects, and presents a case study of a major building project of a new headquarters and media centre for the Danish Broadcasting Corporation in Copenhagen. The building project was actively used as part of a corporate change process......Briefing is not just about specifying needs as requirements but also about evaluating how well design proposals fulfil needs and aspirations. Furthermore, briefing is not only about building design. Briefing starts at the preproject stage to create a basis for the project decision and can include...... a number of different processes with varying purposes before and during the design and construction activities. Thus, briefing can be regarded as a continuous process but it should also be an inclusive and interactive process with the involvement of all stakeholders, including end users. This article...
Inclusive Briefing and User Involvement
DEFF Research Database (Denmark)
Jensen, Per Anker
2011-01-01
Briefing is not just about specifying needs as requirements but also about evaluating how well design proposals fulfil needs and aspirations. Furthermore, briefing is not only about building design. Briefing starts at the preproject stage to create a basis for the project decision and can include...... a number of different processes with varying purposes before and during the design and construction activities. Thus, briefing can be regarded as a continuous process but it should also be an inclusive and interactive process with the involvement of all stakeholders, including end users. This article...... includes a literature study on briefing and user involvement in building projects, and presents a case study of a major building project of a new headquarters and media centre for the Danish Broadcasting Corporation in Copenhagen. The building project was actively used as part of a corporate change process...
Renal involvement in antiphospholipid syndrome.
Pons-Estel, Guillermo J; Cervera, Ricard
2014-02-01
Renal involvement can be a serious problem for patients with antiphospholipid syndrome (APS). However, this complication has been poorly recognized and studied. It can be present in patients who have either primary or systemic lupus erythematosus-associated APS. Clinical and laboratory features of renal involvement in APS include hypertension, hematuria, acute renal failure, and progressive chronic renal insufficiency with mild levels of proteinuria that can progress to nephrotic-range proteinuria. The main lesions are renal artery stenosis, venous renal thrombosis, and glomerular lesions (APS nephropathy) that may be acute (thrombotic microangiopathy) and/or chronic (arteriosclerosis, arterial fibrous intimal hyperplasia, tubular thyroidization, arteriolar occlusions, and focal cortical atrophy). APS can also cause end-stage renal disease and allograft vascular thrombosis. This article reviews the range of renal abnormalities associated with APS, and their diagnosis and treatment options.
Liver involvement in systemic infection
Institute of Scientific and Technical Information of China (English)
Masami; Minemura; Kazuto; Tajiri; Yukihiro; Shimizu
2014-01-01
The liver is often involved in systemic infections,resulting in various types of abnormal liver function test results.In particular,hyperbilirubinemia in the range of 2-10 mg/dL is often seen in patients with sepsis,and several mechanisms for this phenomenon have been proposed.In this review,we summarize how the liver is involved in various systemic infections that are not considered to be primarily hepatotropic.In most patients with systemic infections,treatment for the invading microbes is enough to normalize the liver function tests.However,some patients may show severe liver injury or fulminant hepatic failure,requiring intensive treatment of the liver.
Lupus panniculitis involving the breast
Energy Technology Data Exchange (ETDEWEB)
Sabate, Josep M.; Gomez, Antonio; Torrubia, Sofia; Salinas, Teresa; Clotet, Montse [Universitat Autonoma de Barcelona, Unity of Breast Imaging, Department of Diagnostic Radiology, Hospital de Sant Pau, Barcelona (Spain); Lerma, Enrique [Universitat Autonoma de Barcelona, Department of Pathology, Hospital de Sant Pau, Barcelona (Spain)
2006-01-01
Lupus panniculitis is an unusual immunological disease that characteristically affects the subcutaneous fat and occurs in 2% of patients with systemic lupus erythematosus. We report a case of lupus panniculitis involving the breast, which represents a very uncommon location. Mammographically, it presented as a suspicious irregular mass involving the subcutaneous fat pad with skin thickening. High echogenicity constituted the most relevant sonographic finding. To the best of our knowledge, the magnetic resonance (MR) features have not been previously described. High signal intensity was found on both T1- and T2-weighted precontrast MR images. A dynamic contrast-enhanced study revealed a suspicious focal mass with irregular margins and rim enhancement, with a type 3 time-signal intensity curve. Differential diagnosis with carcinoma and fat necrosis and the value of core biopsy are discussed. (orig.)
Integrating data to acquire new knowledge: Three modes of integration in plant science.
Leonelli, Sabina
2013-12-01
This paper discusses what it means and what it takes to integrate data in order to acquire new knowledge about biological entities and processes. Maureen O'Malley and Orkun Soyer have pointed to the scientific work involved in data integration as important and distinct from the work required by other forms of integration, such as methodological and explanatory integration, which have been more successful in captivating the attention of philosophers of science. Here I explore what data integration involves in more detail and with a focus on the role of data-sharing tools, like online databases, in facilitating this process; and I point to the philosophical implications of focusing on data as a unit of analysis. I then analyse three cases of data integration in the field of plant science, each of which highlights a different mode of integration: (1) inter-level integration, which involves data documenting different features of the same species, aims to acquire an interdisciplinary understanding of organisms as complex wholes and is exemplified by research on Arabidopsis thaliana; (2) cross-species integration, which involves data acquired on different species, aims to understand plant biology in all its different manifestations and is exemplified by research on Miscanthus giganteus; and (3) translational integration, which involves data acquired from sources within as well as outside academia, aims at the provision of interventions to improve human health (e.g. by sustaining the environment in which humans thrive) and is exemplified by research on Phytophtora ramorum. Recognising the differences between these efforts sheds light on the dynamics and diverse outcomes of data dissemination and integrative research; and the relations between the social and institutional roles of science, the development of data-sharing infrastructures and the production of scientific knowledge.
Cardiac involvement in rheumatoid arthritis
Directory of Open Access Journals (Sweden)
V. De Gennaro Colonna
2011-06-01
Full Text Available Rheumatoid arthritis (RA is a systemic disease of unknown etiology characterized by a chronic inflammatory process mainly leading to destruction of synovial membrane of small and major diarthrodial joints. The prevalence of RA within the general adult population is about 1% and female subjects in fertile age result mostly involved. It’s an invalidating disease, associated with changes in life quality and a reduced life expectancy. Moreover, we can observe an increased mortality rate in this population early after the onset of the disease. The mortality excess can be partially due to infective, gastrointestinal, renal or pulmonary complications and malignancy (mainly lung cancer and non- Hodgkin lymphoma. Among extra-articular complications, cardiovascular (CV involvement represents one of the leading causes of morbidity and mortality. Every cardiac structure can be affected by different pathogenic pathways: heart valves, conduction system, myocardium, endocardium, pericardium and coronary arteries. Consequently, different clinical manifestations can be detected, including: pericarditis, myocarditis, myocardial fibrosis, arrhythmias, alterations of conduction system, coronaropathies and ischemic cardiopathy, valvular disease, pulmonary hypertension and heart failure. Considering that early cardiac involvement negatively affects the prognosis, it is mandatory to identify high CV risk RA patients to better define long-term management of this population.
Laryngeal Involvement of Multiple Myeloma
Directory of Open Access Journals (Sweden)
Ariel B. Grobman
2012-01-01
Full Text Available The objectives of this paper are to discuss a rare cause of laryngeal multiple myeloma, to review unique pathologic findings associated with plasma cell neoplasms, to discuss epidemiology, differential diagnosis, and treatment options for plasma cell neoplasms of the larynx. Laryngeal multiple myeloma, also noted in the literature as “metastatic” multiple myeloma, presenting as a de novo laryngeal mass is extremely rare with few reported cases. Laryngeal involvement of extramedullary tumors is reported to be between 6% and 18% with the epiglottis, glottis, false vocal folds, aryepiglottic folds, and subglottis involved in decreasing the order of frequency. We present the case of a 58-year-old male with a history of IgA smoldering myeloma who presented to a tertiary care laryngological practice with a two-month history of dysphonia, which was found to be laryngeal involvement of multiple myeloma. We review the classification of and differentiation between different plasma cell neoplasms, disease workups, pathologic findings, and treatment options.
Analysis of some integrals arising in the atomic three-electron problem
King, Frederick W.
1991-12-01
A detailed analysis is presented for the evaluation of atomic integrals of the form Fri1rj2rk3r-223rm31r12 ne-αr1-βr2-γr3dr1 dr2 dr3, which arise in several contexts of the three-electron atomic problem. All convergent integrals with i>=-2, j>=-2, k>=-2, m>=-1, and n>=-1 are examined. These integrals are solved by two distinct procedures. A majority of the integrals can be evaluated by a reduction of the three-electron integrals to integrals arising in the atomic two-electron integral problem. A second approach allows all integrals with the aforementioned indices to be evaluated by the use of Sack's expansion [J. Math. Phys. 5, 245 (1964)] of the interelectronic separation, which leads to a reduction of the above nine-dimensional integrals to a set of three-dimensional integrals. A discussion is given for the numerical evaluation of the three-dimensional integrals that arise.
Integrated Biomaterials in Tissue Engineering
Ramalingam, Murugan; Ramakrishna, Seeram; Kobayashi, Hisatoshi; Haikel, Youssef
2012-01-01
"Integrated Biomaterials in Tissue Engineering" features all aspects from fundamental principles to current technological advances in biomaterials at the macro/micro/nano/molecular scales suitable for tissue engineering and regenerative medicine. The book is unique as it provides all important aspects dealing with the basic science involved in structure and properties, techniques and technological innovations in material processing and characterizations, and applications of biomaterials in tissue engineering and regenerative medicine.
INTEGRATED MARKETING COMMUNICATION IN POLITICS?
2009-01-01
The current study has practical applicability in politic al domain and theoretical involvement at political marketing communication level. The type of the research is a qualitative one, using as survey methods scientific observation and documentary search. The aim of the research is to prove the applicability of marketing communication concept integrated in political marketing and global marketing communication. There are also exceptions, just analyzing the industry – politics, in which integ...
Histones and genome integrity.
Williamson, Wes D; Pinto, Ines
2012-01-01
Chromosomes undergo extensive structural rearrangements during the cell cycle, from the most open chromatin state required for DNA replication to the highest level of compaction and condensation essential for mitotic segregation of sister chromatids. It is now widely accepted that chromatin is a highly dynamic structure that participates in all DNA-related functions, including transcription, DNA replication, repair, and mitosis; hence, histones have emerged as key players in these cellular processes. We review here the studies that implicate histones in functions that affect the chromosome cycle, defined as the cellular processes involved in the maintenance, replication, and segregation of chromosomal DNA. Disruption of the chromosome cycle affects the integrity of the cellular genome, leading to aneuploidy, polyploidy or cell death. Histone stoichiometry, mutations that affect the structure of the nucleosome core particle, and mutations that affect the structure and/or modifications of the histone tails, all have a direct impact on the fidelity of chromosome transmission and the integrity of the genome.
Polasek, P.; Halamik, J.
1984-05-01
The term semicustom designed integrated circuits denotes integrated circuits of an all purpose character in which the production of chips is completed by using one to three custom design stencil type exposure masks. This involves in most cases interconnecting masks that are used to devise the circuit function desired by the customer. Silicon plates with an all purpose gate matrix are produced up to the interconnection level and can be kept at this phase in storage, after which a customer's specific demands can be met very expediently. All purpose logic fields containing 200 logic gates on a chip and an all purpose chip to be expanded to 1,000 logic gates are discussed. The technology facilitates the devising of fast gates with a delay of approximately 5 ns and power dissipation of 1 mW. In assembly it will be possible to make use of the entire assortment of the currently used casings with 16, 18, 20, 24, 28 and 40 outlets. In addition to the development of the mentioned technology, a general methodology for design of the mentioned gate fields is currently under way.
The integration of angular velocity
Boyle, Michael
2016-01-01
A common problem in physics and engineering is determination of the orientation of an object given its angular velocity. When the direction of the angular velocity changes in time, this is a nontrivial problem involving coupled differential equations. Several possible approaches are examined, along with various improvements over previous efforts. These are then evaluated numerically by comparison to a complicated but analytically known rotation that is motivated by the important astrophysical problem of precessing black-hole binaries. It is shown that a straightforward solution directly using quaternions is most efficient and accurate, and that the norm of the quaternion is irrelevant. Integration of the generator of the rotation can also be made roughly as efficient as integration of the rotation. Both methods will typically be twice as efficient naive vector- or matrix-based methods. Implementation by means of standard general-purpose numerical integrators is stable and efficient, so that such problems can ...
Bosque: integrated phylogenetic analysis software.
Ramírez-Flandes, Salvador; Ulloa, Osvaldo
2008-11-01
Phylogenetic analyses today involve dealing with computer files in different formats and often several computer programs. Although some widely used applications have integrated important functionalities for such analyses, they still work with local resources only: input/output files (users have to manage them) and local computing (users have sometimes to leave their programs, on their desktop computers, running for extended periods of time). To address these problems we have developed 'Bosque', a multi-platform client-server software that performs standard phylogenetic tasks either locally or remotely on servers, and integrates the results on a local relational database. Bosque performs sequence alignments and graphical visualization and editing of trees, thus providing a powerful environment that integrates all the steps of phylogenetic analyses. http://bosque.udec.cl
Singular Integrals with Bilinear Phases
Institute of Scientific and Technical Information of China (English)
Elena PRESTINI
2006-01-01
We prove the boundedness from Lp(T2) to itself, 1 ＜ p ＜∞, of highly oscillatory singular integrals Sf(x, y) presenting singularities of the kind of the double Hilbert transform on a non-rectangular domain of integration, roughly speaking, defined by |y′| ＞ | x′|, and presenting phases λ(Ax + By) with 0 ≤ A, B ≤ 1 and λ≥ 0. The norms of these oscillatory singular integrals are proved to be independent of all parameters A, B and λ involved. Our method extends to a more general family of phases. These results are relevant to problems of almost everywhere convergence of double Fourier and Walsh series.
Interaction between stakeholders and research for integrated river basin management
Jongman, R.H.G.; Padovani, C.R.
2006-01-01
Integrated Water Management calls for basin-wide coordination of activities related to land and water use. The need for multi-stakeholder involvement, the necessity to integrate scientific approaches and local information, the process of mutual communication, the results of discussions on integrated
Strong vector valued integrals
Beckmann, Ralf
2011-01-01
Strong Bochner type integrals with values in locally convex spaces are introduced. It is shown that the strong integral exists in the same cases as the weak (Gelfand-Pettis) integral is known to exist. The strong integral has better continuity properties that the weak integral.
Semantic Web meets Integrative Biology: a survey.
Chen, Huajun; Yu, Tong; Chen, Jake Y
2013-01-01
Integrative Biology (IB) uses experimental or computational quantitative technologies to characterize biological systems at the molecular, cellular, tissue and population levels. IB typically involves the integration of the data, knowledge and capabilities across disciplinary boundaries in order to solve complex problems. We identify a series of bioinformatics problems posed by interdisciplinary integration: (i) data integration that interconnects structured data across related biomedical domains; (ii) ontology integration that brings jargons, terminologies and taxonomies from various disciplines into a unified network of ontologies; (iii) knowledge integration that integrates disparate knowledge elements from multiple sources; (iv) service integration that build applications out of services provided by different vendors. We argue that IB can benefit significantly from the integration solutions enabled by Semantic Web (SW) technologies. The SW enables scientists to share content beyond the boundaries of applications and websites, resulting into a web of data that is meaningful and understandable to any computers. In this review, we provide insight into how SW technologies can be used to build open, standardized and interoperable solutions for interdisciplinary integration on a global basis. We present a rich set of case studies in system biology, integrative neuroscience, bio-pharmaceutics and translational medicine, to highlight the technical features and benefits of SW applications in IB.
Discrete integrable system and its integrable coupling
Institute of Scientific and Technical Information of China (English)
LI Zhu
2009-01-01
This paper derives new discrete integrable system based on discrete isospectral problem. It shows that the hierarchy is completely integrable in the Liouville sense and possesses bi-Hamiltonian structure. Finally, integrable couplings of the obtained system is given by means of semi-direct sums of Lie algebras.
Data integration technologies to support integrated modelling
Knapen, M.J.R.; Roosenschoon, O.R.; Lokers, R.M.; Janssen, S.J.C.; Randen, van Y.; Verweij, P.J.F.M.
2013-01-01
Over the recent years the scientific activities of our organisation in large research projects show a shifting priority from model integration to the integration of data itself. Our work in several large projects on integrated modelling for impact assessment studies has clearly shown the importance
Data integration technologies to support integrated modelling
Knapen, M.J.R.; Roosenschoon, O.R.; Lokers, R.M.; Janssen, S.J.C.; Randen, van Y.; Verweij, P.J.F.M.
2013-01-01
Over the recent years the scientific activities of our organisation in large research projects show a shifting priority from model integration to the integration of data itself. Our work in several large projects on integrated modelling for impact assessment studies has clearly shown the importance
DHA involvement in neurotransmission process
Directory of Open Access Journals (Sweden)
Vancassel Sylvie
2007-05-01
Full Text Available The very high enrichment of the nervous system in the polyunsaturated fatty acids, arachidonic (AA, 20: 4n-6 and docosahexaenoic acids (DHA, 22: 6n-3, is dependant of the dietary availability of their respective precursors, linoleic (18: 2n-6 and_-linolenic acids (18: 3n-3. Inadequate amounts of DHA in brain membranes have been linked to a wide variety of abnormalities ranging from visual acuity and learning irregularities, to psychopathologies. However, the molecular mechanisms involved remain unknown. Several years ago, we hypothesized that a modification of DHA contents of neuronal membranes by dietary modulation could change the neurotransmission function and then underlie inappropriate behavioural response. We showed that, in parallel to a severe loss of brain DHA concomitant to a compensatory substitution by 22:5n-6, the dietary lack of α-linolenic acid during development induced important changes in the release of neurotransmitters (dopamine, serotonin, acetylcholine in cerebral areas specifically involved in learning, memory and reward processes. Data suggested alteration of presynaptic storage process and dysregulations of reciprocal functional interactions between monoaminergic and cholinergic pathways. Moreover, we showed that recovery of these neurochemical changes was possible when the deficient diet was switched to a diet balanced in n-3 and n-6 PUFA before weaning. The next step is to understand the mechanism involved. Particularly, we focus on the study of the metabolic cooperation between the endothelial cell, the astrocyte and the neuron which regulate synaptic transmission.These works could contribute to the understanding of the link between some neuropsychiatric disorders and the metabolism of n-3 PUFA, through their action on neurotransmission.
Neuronal involvement in cisplatin neuropathy
DEFF Research Database (Denmark)
Krarup-Hansen, A; Helweg-Larsen, Susanne Elisabeth; Schmalbruch, H
2007-01-01
Although it is well known that cisplatin causes a sensory neuropathy, the primary site of involvement is not established. The clinical symptoms localized in a stocking-glove distribution may be explained by a length dependent neuronopathy or by a distal axonopathy. To study whether the whole neuron...... of large dorsal root ganglion cells. Motor conduction studies, autonomic function and warm and cold temperature sensation remained unchanged at all doses of cisplatin treatment. The results of these studies are consistent with degeneration of large sensory neurons whereas there was no evidence of distal...
Modeling interdisciplinary activities involving Mathematics
DEFF Research Database (Denmark)
Iversen, Steffen Møllegaard
2006-01-01
In this paper a didactical model is presented. The goal of the model is to work as a didactical tool, or conceptual frame, for developing, carrying through and evaluating interdisciplinary activities involving the subject of mathematics and philosophy in the high schools. Through the terms...... domains (Michelsen, 2001, 2005a, 2005b). Furthermore the theoretical description rest on a series of qualitative interviews with teachers from the Danish high school (grades 9-11) conducted recently. The special case of concrete interdisciplinary activities between mathematics and philosophy is also...
Strategic Integration: The Practical Politics of Integrated Research in Context
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Lorrae van Kerkhoff
2005-01-01
Full Text Available Designing an integrative research program requires that research leaders negotiate a balance between the scientific interest of research and the practical interests of non-scientific partners. This paper examines the ways integrated research is formally categorised, and analyses the tangible expressions of the practical politics involved in reconciling scientific and practical interests. Drawing on a comparative study of two Australian Cooperative Research Centres, I argue that categories used by the research leaders to describe the research programs embody three different strategies for structuring the relationships between researchers and their partners. These include matching research program categories to partners’ implementation program categories, reproducing existing integrative partnership models, and filling gaps in understanding with new technical approaches. These strategies offer different advantages and disadvantages. The cases suggest that the integrative approach favoured by each Centre depended on issues such as the geographic scope of policy arenas, sources of scientific credibility, and the political risks facing partners. The practical politics of research organisation offers a new lens for understanding both the practice and theory of integrated research.
Rotationally invariant ensembles of integrable matrices.
Yuzbashyan, Emil A; Shastry, B Sriram; Scaramazza, Jasen A
2016-05-01
We construct ensembles of random integrable matrices with any prescribed number of nontrivial integrals and formulate integrable matrix theory (IMT)-a counterpart of random matrix theory (RMT) for quantum integrable models. A type-M family of integrable matrices consists of exactly N-M independent commuting N×N matrices linear in a real parameter. We first develop a rotationally invariant parametrization of such matrices, previously only constructed in a preferred basis. For example, an arbitrary choice of a vector and two commuting Hermitian matrices defines a type-1 family and vice versa. Higher types similarly involve a random vector and two matrices. The basis-independent formulation allows us to derive the joint probability density for integrable matrices, similar to the construction of Gaussian ensembles in the RMT.
Rotationally invariant ensembles of integrable matrices
Yuzbashyan, Emil A.; Shastry, B. Sriram; Scaramazza, Jasen A.
2016-05-01
We construct ensembles of random integrable matrices with any prescribed number of nontrivial integrals and formulate integrable matrix theory (IMT)—a counterpart of random matrix theory (RMT) for quantum integrable models. A type-M family of integrable matrices consists of exactly N -M independent commuting N ×N matrices linear in a real parameter. We first develop a rotationally invariant parametrization of such matrices, previously only constructed in a preferred basis. For example, an arbitrary choice of a vector and two commuting Hermitian matrices defines a type-1 family and vice versa. Higher types similarly involve a random vector and two matrices. The basis-independent formulation allows us to derive the joint probability density for integrable matrices, similar to the construction of Gaussian ensembles in the RMT.
Directory of Open Access Journals (Sweden)
Hossein Moradi
2013-01-01
Full Text Available To achieve greater automation of their business processes, organizations face the challenge of integrating disparate systems. In attempting to overcome this problem, organizations are turning to different kinds of enterprise integration. Implementing enterprise integration is a complex task involving both technological and business challenges and requires appropriate middleware technologies. Different enterprise integration solutions provide various functions and features which lead to the complexity of their evaluation process. To overcome this complexity, appropriate tools for evaluating the core integration features of enterprise integration solutions is required. This paper proposes a new comprehensive framework for evaluating the core integration features of both intra-enterprise and inter-enterprise Integration's enabling technologies, which simplify the process of evaluating the requirements met by enterprise integration middleware technologies.The proposed framework for evaluating the core integration features of enterprise integration middleware technologies was enhanced using the structural and conceptual aspects of previous frameworks. It offers a new schema for which various enterprise integration middleware technologies are categorized in different classifications and are evaluated based on their supporting level for the core integration features' criteria. These criteria include the functional and supporting features. The proposed framework, which is a revised version of our previous framework in this area, has developed the scope, structure and content of the mentioned framework.
University involvement in sustainability initiatives
DEFF Research Database (Denmark)
Lehmann, Martin; Christensen, Per; Thrane, Mikkel
2007-01-01
With an outset in the case of Aalborg University, the linkages (actual, potential and missing) between academic work in research & education and sustainability initiatives are explored. The focus is both on the university's core activities as a provider of research and education...... and on the university's activities as an organisation, i.e. its own operation and its accounting for this. Sustainability is defined as a continuous process requiring balance between (the emergence of) problems and our ability and capability to solve them. Some core questions that this paper seeks to answer are: "How......, human, institutional and economic impacts and explores how core knowledge developed through research and education is or is not used in this context. Finally, the paper provides a scenario for opportunities to strengthen the university outreach and for it to become more active in a more integrated...
Hydrography - Integrated List Attaining
NSGIC GIS Inventory (aka Ramona) — This layer shows only attaining segments of the Integrated List. The Streams Integrated List represents stream assessments in an integrated format for the Clean...
Renal involvement in antiphospholipid syndrome.
Sciascia, Savino; Cuadrado, Maria José; Khamashta, Munther; Roccatello, Dario
2014-05-01
Antiphospholipid syndrome (APS) is an autoimmune disease defined by the presence of arterial or venous thrombotic events and/or pregnancy morbidity in patients who test positive for antiphospholipid antibodies (aPLs). APS can be isolated (known as primary APS) or associated with other autoimmune diseases, such as systemic lupus erythematosus (SLE; known as secondary APS). The kidney is a major target organ in APS and renal thrombosis can occur at any level within the vasculature of the kidney (renal arteries, intrarenal arteries, glomerular capillaries and renal veins); events reflect the site and size of the involved vessels. Histological findings vary widely, including ischaemic glomeruli and thrombotic lesions without glomerular or arterial immune deposits on immunofluorescence. Renal prognosis is affected by the presence of aPLs in patients with lupus nephritis and can be poor. In patients with SLE and aPLs, biopsy should be performed because inflammatory and thrombotic lesions require different therapeutic approaches. Renal involvement in patients with definite APS is treated by anticoagulation with long-term warfarin. The range of renal manifestations associated with APS is broadening and, therefore, aPLs have increasing relevance in end-stage renal disease, transplantation and pregnancy.
Subfascial involvement in glomuvenous malformation
Energy Technology Data Exchange (ETDEWEB)
Shaikh, Raja; Alomari, Ahmad I.; Chaudry, Gulraiz [Boston Children' s Hospital, Division of Interventional Radiology, Boston, MA (United States); Mulliken, John B. [Boston Children' s Hospital, Division of Plastic Surgery, Boston, MA (United States); Fishman, Steven J. [Boston Children' s Hospital, Department of Surgery, Boston, MA (United States); Kozakewich, Harry P.W. [Boston Children' s Hospital, Department of Pathology, Boston, MA (United States)
2014-07-15
Glomuvenous malformation (GVM) is an inherited autosomal dominant trait. The lesions, which appear as bluish nodules or plaque-like cutaneous elevations, are usually tender and more firm than sporadic venous malformations. Conventionally, the lesions are thought to be limited to the cutaneous and subcutaneous tissue planes. The objective was to characterize the depth of involvement of GVM lesions. Magnetic resonance imaging (MRI) findings in GVM were retrospectively evaluated by two radiologists. The signal characteristics, tissue distribution, pattern of contrast enhancement of the lesions in GVM were documented. Thirty patients (19 female) aged 1-35 years (mean 18 years) were diagnosed with GVM based on clinical features (n = 20) and/or histopathological findings (n = 10). The lesions were present in the lower extremity (n = 15), upper extremity (n = 6), cervico-facial region (n = 6), pelvis (n = 2), and chest wall (n = 1). All patients had skin and subcutaneous lesions. Fifty percent of the patients (n = 15) demonstrated subfascial intramuscular (n = 15), intra-osseous (n = 1), and intra-articular involvement (n = 1). Contrary to the conventional belief that GVMs are generally limited to the skin and subcutaneous tissue, deep subfascial extension of the lesions is common. (orig.)
Simplification of integrity constraints for data integration
DEFF Research Database (Denmark)
Christiansen, Henning; Martinenghi, Davide
2004-01-01
When two or more databases are combined into a global one, integrity may be violated even when each database is consistent with its own local integrity constraints. Efficient methods for checking global integrity in data integration systems are called for: answers to queries can then be trusted......, because either the global database is known to be consistent or suitable actions have been taken to provide consistent views. The present work generalizes simplification techniques for integrity checking in traditional databases to the combined case. Knowledge of local consistency is employed, perhaps...... together with given a priori constraints on the combination, so that only a minimal number of tuples needs to be considered. Combination from scratch, integration of a new source, and absorption of local updates are dealt with for both the local-as-view and global-as-view approaches to data integration....
Tactical Systems Integration Laboratory
Federal Laboratory Consortium — The Tactical Systems Integration Laboratory is used to design and integrate computer hardware and software and related electronic subsystems for tactical vehicles....
Lui, M; Chan, Andy; Long, Josh
2011-01-01
Pro Spring Integration is an authoritative book from the experts that guides you through the vast world of enterprise application integration (EAI) and application of the Spring Integration framework towards solving integration problems. The book is:. * An introduction to the concepts of enterprise application integration * A reference on building event-driven applications using Spring Integration * A guide to solving common integration problems using Spring Integration What makes this book unique is its coverage of contemporary technologies and real-world information, with a focus on common p
Bagci, A
2016-01-01
The author in his previous works were presented a numerical integration method, namely, global-adaptive with the Gauss-Kronrod numerical integration extension in order to accurate calculation of molecular auxiliary functions integrals involve power functions with non-integer exponents. They are constitute elements of molecular integrals arising in Dirac equation when Slater-type orbitals with non-integer principal quantum numbers are used. Binomial series representation of power functions method, so far, is used for analytical evaluation of the molecular auxiliary function integrals however, intervals of integration cover areas beyond the condition of convergence. In the present study, analytical evaluation of these integrals is re-examined. They are expressed via prolate spheroidal coordinates. An alternative analytical approximation are derived. Slowly convergent binomial series representation formulae for power functions is investigated through nonlinear sequence transformations for the acceleration of con...
Evans, Eliza D.; McFarland, Daniel A.; Rios-Aguilar, Cecilia; Deil-Amen, Regina
2016-01-01
Objective: This study explores the relationship between online social network involvement and academic outcomes among community college students. Prior theory hypothesizes that socio-academic moments are especially important for the integration of students into community colleges and that integration is related to academic outcomes. Online social…
Cutaneous Plasmacytosis with Perineural Involvement
Directory of Open Access Journals (Sweden)
Elizabeth A. Brezinski
2014-01-01
Full Text Available Importance. Cutaneous and systemic plasmacytosis are rare conditions of unknown etiology with characteristic red-brown skin lesions and a mature polyclonal plasma cell infiltrate within the dermis. Perineural plasma cell infiltrates may be a histologic clue to the diagnosis of cutaneous plasmacytosis. Observations. Our patient had a five-year history of persistent reddish-brown plaques on the neck and trunk without systemic symptoms. Histologic examination showed dermal perivascular and perineural plasma cells with excess lambda light chain expression. Due to decreased quality of life caused by his skin lesions, he was placed on a chemotherapeutic regimen with bortezomib. Conclusions and Relevance. The patient was diagnosed with cutaneous plasmacytosis based on classic histopathology results with a recently characterized pattern of perineural involvement. Bortezomib therapy was initiated to manage his skin eruption, which has not been previously described as a treatment for this chronic condition.
Modeling interdisciplinary activities involving Mathematics
DEFF Research Database (Denmark)
Iversen, Steffen Møllegaard
2006-01-01
In this paper a didactical model is presented. The goal of the model is to work as a didactical tool, or conceptual frame, for developing, carrying through and evaluating interdisciplinary activities involving the subject of mathematics and philosophy in the high schools. Through the terms...... of Horizontal Intertwining, Vertical Structuring and Horizontal Propagation the model consists of three phases, each considering different aspects of the nature of interdisciplinary activities. The theoretical modelling is inspired by work which focuses on the students abilities to concept formation in expanded...... domains (Michelsen, 2001, 2005a, 2005b). Furthermore the theoretical description rest on a series of qualitative interviews with teachers from the Danish high school (grades 9-11) conducted recently. The special case of concrete interdisciplinary activities between mathematics and philosophy is also...
2002-01-01
The encouragement of individual members of staff to contribute to the work of the task forces by making suggestions via the form on the Users'page of the web has been successful. Therefore, as announced by the Director General in his talk to the Staff in April, the management would like staff to continue to be involved in the change process by making further suggestions. Suggestions received will be distributed to the Director(s)/Division Leader(s) concerned, for reply and action where appropriate. The Director General has set up a small Panel that will ensure the proper processing of the ideas and will present a regular overview to the Director General. Members of the Panel are: Jan van der Boon, Vincent Hatton, Karl-Heinz Kissler, Thomas Pettersson, Florian Sonnemann, and Horst Wenninger.
Metronidazole neurotoxicity: Sequential neuroaxis involvement
Directory of Open Access Journals (Sweden)
Kyung-Il Park
2011-01-01
Full Text Available Neurological manifestation of metronidazole toxicity include neuropathy and encephalopathy. We report a 67-year-old man with progressive painful paresthesias involving all the four limbs of 3 weeks′ duration before admission. He had been treated with metronidazole and cephalosporin for 10 weeks for a hepatic abscess. Five weeks after the symptom onset, he complained of dysarthria and limb ataxia. Magnetic resonance imaging revealed signal abnormalities in the splenium of the corpus callosum and bilateral dentate nuclei. A few hours after brain imaging, the patient exhibited excessive diaphoresis and fluctuation in blood pressure, which resolved within several hours after discontinuation of metronidazole. Whereas his speech returned to near normal within approximately 1 week, a burning sensation was not completely relieved, even 6 months after discharge.
Charmless B decays involving baryons
Gronau, Michael; Rosner, Jonathan L.
1988-02-01
Predictions are made for the fraction of B-meson decays involving specific final states of NN¯+nπ (n>=0), as functions of (a) decay dynamics, (b) models for multipion production, (c) the isospin of the final state, and (d) the ratio ||Vbu/Vbc|| of Kobayashi-Maskawa matrix elements. From recent observations of B+-->pp¯π+(+c.c.) and B0-->pp¯π+π- by the ARGUS Collaboration, it is concluded that ||Vbu/Vbc||>~0.08, similar to the ARGUS Collaboration's own estimate of 0.07. However, a more likely value for this ratio is near its present experimental upper limit. Predictions are made for further final states in NN¯+nπ and in other charmless B decays. We also comment briefly on prospects for observing CP violation in B-->NN¯+nπ.
Measuring Purchase‐decision involvement ,
Directory of Open Access Journals (Sweden)
Naser Azad
2014-08-01
Full Text Available Nowadays, increasing competition is forcing businesses to pay more attention on customer satisfaction providing strong customer services. Increased competition has also increased marketing activities. This paper presents an empirical investigation to determine important factors influencing purchase decision involvement in food industry in city of Tehran, Iran. The study designs a questionnaire in Likert scale, distributes it among 270 experts in food industry and, using principle component (PCA analysis, extracts important group of factors. The questionnaire consists of 27 questions, which is reduced to 23 questions because of sensitivity of the PCA to Skewness of data. Cronbach alpha is calculated as 0.81, which is well above the minimum acceptable level. The results indicate that there were four factors including individual differences, product validation, triggers and dependent behavior influencing purchasing decisions.
Kidney involvement in rheumatoid arthritis
Directory of Open Access Journals (Sweden)
P. Lazzarini
2011-09-01
Full Text Available Rheumatoid Arthritis (RA is a widespread disease and its renal involvement, relatively common, is clinically significant because worsens course and mortality of the primary disease. There is still no agreement on the prevalence of renal disorders in RA: data analysis originates from different sources, as death certificates, autopsies, clinical and laboratory findings and kidney biopsies, each with its limitations. Histoimmunological studies on bioptical specimens of patients with RA and kidney damage, led to clarify prevalent pathologies. In order of frequency: glomerulonephritis and amyloidosis (60-65% and 20-30% respectively, followed by acute or chronic interstitial nephritis. Kidney injury during RA includes secondary renal amyloidosis, nephrotoxic effects of antirheumatic drugs and nephropathies as extra-articular manifestations (rheumatoid nephropathy. Amyloidosis affects survival, increases morbidity and is the main cause of end stage renal disease in patients with RA and nephropathy. Strong association between RA activity and amyloidosis needs the use of immunosuppressive and combined therapies, to prevent this complication and reduce risk of dialysis. Long-lasting and combined RA pharmacotherapy involves various renal side effects. In this review we describe NSAIDs and DMARDs (Disease-Modifying Antirheumatic Drugs nephrotoxicity, particularly by gold compounds, D-penicillamine, cyclosporine A and methotrexate. Rare cases of IgA glomerulonephritis during immunomodulating therapy with leflunomide and TNF blocking receptor (etanercept are reported; real clinical significance of this drug-related nephropathy will be established by development of RA treatment. In RA nephropathies, mesangial glomerulonephritis is the most frequent histological lesion (35-60 % out of biopsies from patients with urinary abnormalities and/or kidney impairment, followed by minimal change glomerulopathy (3-14% and p-ANCA positive necrotizing crescentic
Drug hypersensitivity reactions involving skin.
Hausmann, Oliver; Schnyder, Benno; Pichler, Werner J
2010-01-01
Immune reactions to drugs can cause a variety of diseases involving the skin, liver, kidney, lungs, and other organs. Beside immediate, IgE-mediated reactions of varying degrees (urticaria to anaphylactic shock), many drug hypersensitivity reactions appear delayed, namely hours to days after starting drug treatment, showing a variety of clinical manifestations from solely skin involvement to fulminant systemic diseases which may be fatal. Immunohistochemical and functional studies of drug-specific T cells in patients with delayed reactions confirmed a predominant role for T cells in the onset and maintenance of immune-mediated delayed drug hypersensitivity reactions (type IV reactions). In these reactions, drug-specific CD4+ and CD8+ T cells are stimulated by drugs through their T cell receptors (TCR). Drugs can stimulate T cells in two ways: they can act as haptens and bind covalently to larger protein structures (hapten-carrier model), inducing a specific immune response. In addition, they may accidentally bind in a labile, noncovalent way to a particular TCR of the whole TCR repertoire and possibly also major histocompatibility complex (MHC)-molecules - similar to their pharmacologic action. This seems to be sufficient to reactivate certain, probably in vivo preactivated T cells, if an additional interaction of the drug-stimulated TCR with MHC molecules occurs. The mechanism was named pharmacological interaction of a drug with (immune) receptor and thus termed the p-i concept. This new concept may explain the frequent skin symptoms in drug hypersensitivity to oral or parenteral drugs. Furthermore, the various clinical manifestations of T cell-mediated drug hypersensitivity may be explained by distinct T cell functions leading to different clinical phenotypes. These data allowed a subclassification of the delayed hypersensitivity reactions (type IV) into T cell reactions which, by releasing certain cytokines and chemokines, preferentially activate and recruit
Energy Technology Data Exchange (ETDEWEB)
Bordenave-Montesquieu, A.; Benoit-Cattin, P.; Gleizes, A.; Marrakchi, A.I.; Dousson, S.; Hitz, D.
1984-04-14
Double electron transfer into autoionising states N/sup 4 +/(1snln'l'), with n = 2,3,4 and n' >= n has been observed in a collision between a one-electron highly charged N/sup 6 +/(1s) ion and a two-electron target (He or H/sub 2/), by electron spectrometry. The same configurations are excited in the two collisional systems but with very different probabilities. Electron capture mainly occurs into 1s2ln'l' in He-systems whereas transfer into 1s3ln'l' is stronger in H/sub 2/ systems.
Integrative Medicine in Head and Neck Cancer.
Matovina, Chloe; Birkeland, Andrew C; Zick, Suzanna; Shuman, Andrew G
2017-02-01
Objective Complementary and alternative medicine, or integrative medicine, has become increasingly popular among patients with head and neck cancer. Despite its increasing prevalence, many patients feel uncomfortable discussing such therapies with their physicians, and many physicians are unaware and underequipped to evaluate or discuss their use with patients. The aim of this article is to use recent data to outline the decision making inherent to integrative medicine utilization among patients with head and neck cancer, to discuss the ethical implications inherent to balancing integrative and conventional approaches to treatment, and to highlight available resources to enhance head and neck cancer providers' understanding of integrative medicine. Data Sources Randomized controlled trials involving integrative medicine or complementary and alternative medicine treatment for cancer patients. Review Methods Trials were drawn from a systematic PubMed database search categorized into cancer prevention, treatment, and symptom management. Conclusions Integrative medicine is gaining popularity for the management of cancer and is most commonly used for symptom management. A number of randomized controlled trials provide data to support integrative therapies, yet physicians who treat head and neck cancer may be faced with ethical dilemmas and practical barriers surrounding incorporation of integrative medicine. Implications for Practice In the management of head and neck cancer, there is an increasing demand for awareness of, dialogue about, and research evaluating integrative medicine therapies. It is important for otolaryngologists to become aware of integrative therapy options, their risks and benefits, and resources for further information to effectively counsel their patients.
Bernheim, Jan L; Distelmans, Wim; Mullie, Arsène; Ashby, Michael A
2014-12-01
This article analyses domestic and foreign reactions to a 2008 report in the British Medical Journal on the complementary and, as argued, synergistic relationship between palliative care and euthanasia in Belgium. The earliest initiators of palliative care in Belgium in the late 1970s held the view that access to proper palliative care was a precondition for euthanasia to be acceptable and that euthanasia and palliative care could, and should, develop together. Advocates of euthanasia including author Jan Bernheim, independent from but together with British expatriates, were among the founders of what was probably the first palliative care service in Europe outside of the United Kingdom. In what has become known as the Belgian model of integral end-of-life care, euthanasia is an available option, also at the end of a palliative care pathway. This approach became the majority view among the wider Belgian public, palliative care workers, other health professionals, and legislators. The legal regulation of euthanasia in 2002 was preceded and followed by a considerable expansion of palliative care services. It is argued that this synergistic development was made possible by public confidence in the health care system and widespread progressive social attitudes that gave rise to a high level of community support for both palliative care and euthanasia. The Belgian model of so-called integral end-of-life care is continuing to evolve, with constant scrutiny of practice and improvements to procedures. It still exhibits several imperfections, for which some solutions are being developed. This article analyses this model by way of answers to a series of questions posed by Journal of Bioethical Inquiry consulting editor Michael Ashby to the Belgian authors.
Preparing Health Care Processes for IT Integration
DEFF Research Database (Denmark)
Walley, Paul; Laursen, Martin Lindgård
2005-01-01
Many health care supply chains are now attempting to achieve greater IT integration, between primary and secondary care, as well as internal integration within hospital systems. Conventional theory suggests that these types of initiative should coincide with extensive process reengineering...... effectiveness and efficiency of the system. Using data from two countries and involving 200 hospitals, the paper addresses the current state of determinacy of processes and explores the potential route towards standardisation. We hypothesise that management paradigms such as “lean thinking...
Towards service integration in electronic government implementations
Asa'd, Asa'd M.; Khazaei, Babak; Akhgar, Babak; Alqatawna, Ja'far
2016-01-01
Service integration is one of the most critical issues affecting electronic government implementations all over the world. Providing integrated services to citizens, businesses, and all other stakeholders involved in electronic government activities at "one stop portal" is considered to be a big opportunity for governments to improve their services’ efficiency and effectiveness. This paper aims to provide a general background and theoretical foundation towards understanding the role of ...
Impact of traffic states on freeway crash involvement rates.
Yeo, Hwasoo; Jang, Kitae; Skabardonis, Alexander; Kang, Seungmo
2013-01-01
Freeway traffic accidents are complicated events that are influenced by multiple factors including roadway geometry, drivers' behavior, traffic conditions and environmental factors. Among the various factors, crash occurrence on freeways is supposed to be strongly influenced by the traffic states representing driving situations that are changed by road geometry and cause the change of drivers' behavior. This paper proposes a methodology to investigate the relationship between traffic states and crash involvements on the freeway. First, we defined section-based traffic states: free flow (FF), back of queue (BQ), bottleneck front (BN) and congestion (CT) according to their distinctive patterns; and traffic states of each freeway section are determined based on actual measurements of traffic data from upstream and downstream ends of the section. Next, freeway crash data are integrated with the traffic states of a freeway section using upstream and downstream traffic measurements. As an illustrative study to show the applicability, we applied the proposed method on a 32-mile section of I-880 freeway. By integrating freeway crash occurrence and traffic data over a three-year period, we obtained the crash involvement rate for each traffic state. The results show that crash involvement rate in BN, BQ, and CT states are approximately 5 times higher than the one in FF. The proposed method shows promise to be used for various safety performance measurement including hot spot identification and prediction of the number of crash involvements on freeway sections.
Numerical Integration with Derivatives
Institute of Scientific and Technical Information of China (English)
Hu Cheng
2006-01-01
A new formula with derivatives for numerical integration was presented. Based on this formula and the Richardson extrapolation process, a numerical integration method was established. It can converge faster than the Romberg's. With the same accuracy, the computation of the new numerical integration with derivatives is only half of that of Romberg's numerical integration.
The integrated PWR; Les REP integres
Energy Technology Data Exchange (ETDEWEB)
Gautier, G.M. [CEA Cadarache, 13 - Saint-Paul-lez-Durance (France). Dept. d' Etudes des Reacteurs
2002-07-01
This document presents the integrated reactors concepts by a presentation of four reactors: PIUS, SIR, IRIS and CAREM. The core conception, the operating, the safety, the economical aspects and the possible users are detailed. From the performance of the classical integrated PWR, the necessity of new innovative fuels utilization, the research of a simplified design to make easier the safety and the KWh cost decrease, a new integrated reactor is presented: SCAR 600. (A.L.B.)
Project Integration Architecture
Jones, William Henry
2008-01-01
The Project Integration Architecture (PIA) is a distributed, object-oriented, conceptual, software framework for the generation, organization, publication, integration, and consumption of all information involved in any complex technological process in a manner that is intelligible to both computers and humans. In the development of PIA, it was recognized that in order to provide a single computational environment in which all information associated with any given complex technological process could be viewed, reviewed, manipulated, and shared, it is necessary to formulate all the elements of such a process on the most fundamental level. In this formulation, any such element is regarded as being composed of any or all of three parts: input information, some transformation of that input information, and some useful output information. Another fundamental principle of PIA is the assumption that no consumer of information, whether human or computer, can be assumed to have any useful foreknowledge of an element presented to it. Consequently, a PIA-compliant computing system is required to be ready to respond to any questions, posed by the consumer, concerning the nature of the proffered element. In colloquial terms, a PIA-compliant system must be prepared to provide all the information needed to place the element in context. To satisfy this requirement, PIA extends the previously established object-oriented- programming concept of self-revelation and applies it on a grand scale. To enable pervasive use of self-revelation, PIA exploits another previously established object-oriented-programming concept - that of semantic infusion through class derivation. By means of self-revelation and semantic infusion through class derivation, a consumer of information can inquire about the contents of all information entities (e.g., databases and software) and can interact appropriately with those entities. Other key features of PIA are listed.