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Sample records for two-component phase doppler

  1. Application of two-component phase doppler interferometry to the measurement of particle size, mass flux, and velocities in two-phase flows

    OpenAIRE

    McDonell, VG; Samuelsen, GS

    1989-01-01

    The application of two-component interferometry is described for the spatially-resolved measurement of particle size, velocity and mass flux as well as continuous phase velocity. Such a capability is important to develop an understanding of the physical processes attendant to two-phase flow systems, especially those involving liquid atomization typical of a wide class of combustion systems. Adapted from laser anemometry, the technique (phase Doppler interferometry) measures single particle ev...

  2. Experimental study of wind tunnel performance by a two-component laserDopplerAnemometer

    Directory of Open Access Journals (Sweden)

    M Pourmahabadian

    2005-10-01

    Full Text Available Background and Aims: This survey studies the wind tunnel performance by a two- componentlaser Doppler Anemometer, so some experiments were carried out to assess the performance of awind tunnel.Method: The tunnel was capable to produce air velocity of up to 40 m/s.. Measurements ofvelocity profiles have been made actors the test section of wind tunnel through the using a twocomponentfiber optic Laser Doppler anemometer. Measurements of velocity profiles andturbulence intensities have been made across the test section of the wind tunnel using a twocomponentfiber optic Laser Doppler anemometer (I.D.A for wind speeds ranging from 1 to3m/s.Results: Performance rests of velocity profiles at a given flow rate and various position of aerosolgenerator showed that although uniformity of flow dependent to the place of an atomizer (asaerosol generator but the variation of wind speed across the test section meets the wind speedrequirements, as specified by US EPAfor 3m/s only.Conclusion:At time which particles velocity reach to less than one micron, the air velocity relateson the similarity of particles and

  3. Two-component thermosensitive hydrogels : Phase separation affecting rheological behavior

    NARCIS (Netherlands)

    Abbadessa, Anna; Landín, Mariana; Oude Blenke, Erik; Hennink, Wim E.; Vermonden, Tina

    2017-01-01

    Extracellular matrices are mainly composed of a mixture of different biopolymers and therefore the use of two or more building blocks for the development of tissue-mimicking hydrogels is nowadays an attractive strategy in tissue-engineering. Multi-component hydrogel systems may undergo phase

  4. Glare Spot Phase Doppler Anemometry

    OpenAIRE

    Hespel, Camille; Ren, Kuan Fang; Gréhan, Gérard; Onofri, Fabrice

    2006-01-01

    International audience; The Phase Doppler anemometry has been developed to measure simultaneously the velocity and the size of droplets. The measurement of the refractive index is also necessary since it depends on the temperature and the composition of the particle and its measurement permits both to increase the quality of the diameter measurement and to obtain information on the temperature and/or the composition of the droplets. In this paper, we introduce a Glare Spot Phase Doppler Anemo...

  5. Anisotropic properties of phase separation in two-component dipolar Bose-Einstein condensates

    Science.gov (United States)

    Wang, Wei; Li, Jinbin

    2018-03-01

    Using Crank-Nicolson method, we calculate ground state wave functions of two-component dipolar Bose-Einstein condensates (BECs) and show that, due to dipole-dipole interaction (DDI), the condensate mixture displays anisotropic phase separation. The effects of DDI, inter-component s-wave scattering, strength of trap potential and particle numbers on the density profiles are investigated. Three types of two-component profiles are present, first cigar, along z-axis and concentric torus, second pancake (or blood cell), in xy-plane, and two non-uniform ellipsoid, separated by the pancake and third two dumbbell shapes.

  6. Glare Spot Phase Doppler Anemometry

    Science.gov (United States)

    Hespel, Camille; Ren, Kuanfang; Gréhan, Gérard; Onofri, Fabrice

    2007-06-01

    The Phase Doppler anemometry has been developed to measure simultaneously the velocity and the size of droplets. The measurement of the refractive index would be also interesting since it depends on the temperature and the composition of the particle and its measurement permits both to increase the quality of the diameter measurement and to obtain information on the temperature and/or the composition of the droplets. In this paper, we introduce a Glare Spot Phase Doppler Anemometry which uses two large beams. In this case, the images of the particle formed by the reflected and refracted light, known as glare spots, are separated in space. When a particle passes in the probe volume, the two parts in a signal obtained by a detector in forward direction are then separated in time. If two detectors are used the phase differences between two signals, the distance and the intensity ratio of reflected and refracted parts can be obtained and they provide rich information about the particle diameter and its refractive index, as well as its velocity. This paper is devoted to the numerical study of such a configuration with two theoretical models: geometrical optics and rigorous electromagnetism solution.

  7. Phase diagram of two-component bosons on an optical lattice

    International Nuclear Information System (INIS)

    Altman, Ehud; Hofstetter, Walter; Demler, Eugene; Lukin, Mikhail D

    2003-01-01

    We present a theoretical analysis of the phase diagram of two-component bosons on an optical lattice. A new formalism is developed which treats the effective spin interactions in the Mott and superfluid phases on the same footing. Using this new approach we chart the phase boundaries of the broken spin symmetry states up to the Mott to superfluid transition and beyond. Near the transition point, the magnitude of spin exchange can be very large, which facilitates the experimental realization of spin-ordered states. We find that spin and quantum fluctuations have a dramatic effect on the transition, making it first order in extended regions of the phase diagram. When each species is at integer filling, an additional phase transition may occur, from a spin-ordered insulator to a Mott insulator with no broken symmetries. We determine the phase boundaries in this regime and show that this is essentially a Mott transition in the spin sector

  8. Analysis of water hammer in two-component two-phase flows

    International Nuclear Information System (INIS)

    Warde, H.; Marzouk, E.; Ibrahim, S.

    1989-01-01

    The water hammer phenomena caused by a sudden valve closure in air-water two-phase flows must be clarified for the safety analysis of LOCA in reactors and further for the safety of boilers, chemical plants, pipe transport of fluids such as petroleum and natural gas. In the present work water hammer phenomena caused by sudden valve closure in two-component two-phase flows are investigated theoretically and experimentally. The phenomena are more complicated than in single phase-flows due to the fact of the presence of compressible component. Basic partial differential equations based on a one-dimensional homogeneous flow model are solved by the method of characteristic. The analysis is extended to include friction in a two-phase mixture depending on the local flow pattern. The profiles of the pressure transients, the propagation velocity of pressure waves and the effect of valve closure on the transient pressure are found. Different two-phase flow pattern and frictional pressure drop correlations were used including Baker, Chesholm and Beggs and Bril correlations. The effect of the flow pattern on the characteristic of wave propagation is discussed primarily to indicate the effect of void fraction on the velocity of wave propagation and on the attenuation of pressure waves. Transient pressure in the mixture were recorded at different air void fractions, rates of uniform valve closure and liquid flow velocities with the aid of pressure transducers, transient wave form recorders interfaced with an on-line pc computer. The results are compared with computation, and good agreement was obtained within experimental accuracy

  9. Critical point of gas-liquid type phase transition and phase equilibrium functions in developed two-component plasma model.

    Science.gov (United States)

    Butlitsky, M A; Zelener, B B; Zelener, B V

    2014-07-14

    A two-component plasma model, which we called a "shelf Coulomb" model has been developed in this work. A Monte Carlo study has been undertaken to calculate equations of state, pair distribution functions, internal energies, and other thermodynamics properties. A canonical NVT ensemble with periodic boundary conditions was used. The motivation behind the model is also discussed in this work. The "shelf Coulomb" model can be compared to classical two-component (electron-proton) model where charges with zero size interact via a classical Coulomb law. With important difference for interaction of opposite charges: electrons and protons interact via the Coulomb law for large distances between particles, while interaction potential is cut off on small distances. The cut off distance is defined by an arbitrary ɛ parameter, which depends on system temperature. All the thermodynamics properties of the model depend on dimensionless parameters ɛ and γ = βe(2)n(1/3) (where β = 1/kBT, n is the particle's density, kB is the Boltzmann constant, and T is the temperature) only. In addition, it has been shown that the virial theorem works in this model. All the calculations were carried over a wide range of dimensionless ɛ and γ parameters in order to find the phase transition region, critical point, spinodal, and binodal lines of a model system. The system is observed to undergo a first order gas-liquid type phase transition with the critical point being in the vicinity of ɛ(crit) ≈ 13(T(*)(crit) ≈ 0.076), γ(crit) ≈ 1.8(v(*)(crit) ≈ 0.17), P(*)(crit) ≈ 0.39, where specific volume v* = 1/γ(3) and reduced temperature T(*) = ɛ(-1).

  10. Measuring two-phase and two-component mixtures by radiometric technique

    International Nuclear Information System (INIS)

    Mackuliak, D.; Rajniak, I.

    1984-01-01

    The possibility was tried of the application of the radiometric method in measuring steam water content. The experiments were carried out in model conditions where steam was replaced with the two-component mixture of water and air. The beta radiation source was isotope 204 Tl (Esub(max)=0.765 MeV) with an activity of 19.35 MBq. Measurements were carried out within the range of the surface density of the mixture from 0.119 kg.m -2 to 0.130 kg.m -2 . Mixture speed was 5.1 m.s -1 to 7.1 m.s -1 . The observed dependence of relative pulse frequency on the specific water content in the mixture was approximated by a linear regression. (B.S.)

  11. Stability conditions and phase diagrams for two-component Fermi gases with population imbalance

    International Nuclear Information System (INIS)

    Chen Qijin; He Yan; Chien, C.-C.; Levin, K.

    2006-01-01

    Superfluidity in atomic Fermi gases with population imbalance has recently become an exciting research focus. There is considerable disagreement in the literature about the appropriate stability conditions for states in the phase diagram throughout the BCS to Bose-Einstein condensation crossover. Here we discuss these stability conditions for homogeneous polarized superfluid phases, and compare with recent alternative proposals. The requirement of a positive second-order partial derivative of the thermodynamic potential with respect to the fermionic excitation gap Δ (at fixed chemical potentials) is demonstrated to be equivalent to the positive definiteness of the particle number susceptibility matrix. In addition, we show the positivity of the effective pair mass constitutes another nontrivial stability condition. These conditions determine the (local) stability of the system towards phase separation (or other ordered phases). We also study systematically the effects of finite temperature and the related pseudogap on the phase diagrams defined by our stability conditions

  12. Phase Transitions in Definite Total Spin States of Two-Component Fermi Gases.

    Science.gov (United States)

    Yurovsky, Vladimir A

    2017-05-19

    Second-order phase transitions have no latent heat and are characterized by a change in symmetry. In addition to the conventional symmetric and antisymmetric states under permutations of bosons and fermions, mathematical group-representation theory allows for non-Abelian permutation symmetry. Such symmetry can be hidden in states with defined total spins of spinor gases, which can be formed in optical cavities. The present work shows that the symmetry reveals itself in spin-independent or coordinate-independent properties of these gases, namely as non-Abelian entropy in thermodynamic properties. In weakly interacting Fermi gases, two phases appear associated with fermionic and non-Abelian symmetry under permutations of particle states, respectively. The second-order transitions between the phases are characterized by discontinuities in specific heat. Unlike other phase transitions, the present ones are not caused by interactions and can appear even in ideal gases. Similar effects in Bose gases and strong interactions are discussed.

  13. Quantum-phase dynamics of two-component Bose-Einstein condensates: Collapse-revival of macroscopic superposition states

    International Nuclear Information System (INIS)

    Nakano, Masayoshi; Kishi, Ryohei; Ohta, Suguru; Takahashi, Hideaki; Furukawa, Shin-ichi; Yamaguchi, Kizashi

    2005-01-01

    We investigate the long-time dynamics of two-component dilute gas Bose-Einstein condensates with relatively different two-body interactions and Josephson couplings between the two components. Although in certain parameter regimes the quantum state of the system is known to evolve into macroscopic superposition, i.e., Schroedinger cat state, of two states with relative atom number differences between the two components, the Schroedinger cat state is also found to repeat the collapse and revival behavior in the long-time region. The dynamical behavior of the Pegg-Barnett phase difference between the two components is shown to be closely connected with the dynamics of the relative atom number difference for different parameters. The variation in the relative magnitude between the Josephson coupling and intra- and inter-component two-body interaction difference turns out to significantly change not only the size of the Schroedinger cat state but also its collapse-revival period, i.e., the lifetime of the Schroedinger cat state

  14. Pressure waves in bubble, two-component, two-phase flows. Theoretical approach

    International Nuclear Information System (INIS)

    Micaelli, J.C.

    1982-05-01

    Common methods of modelling pressure waves (global or acoustic) and their inadequacy are described. A model is proposed, based on a stochastic treatment of the gaseous phase. Different mechanisms which affect pressure wave propagation are analysed. The importance of interfacial momentum and heat transfer is confirmed [fr

  15. Temperature-controlled structure and kinetics of ripple phases in one- and two-component supported lipid bilayers

    DEFF Research Database (Denmark)

    Kaasgaard, Thomas; Leidy, Chad; Crowe, J.H.

    2003-01-01

    Temperature-controlled atomic force microscopy (AFM) has been used to visualize and study the structure and kinetics of ripple phases in one-component dipalmitoylphosphaticlylcholine (DPPC) and two-component dimyristoylphosphatidylcholine-distearoylphosphatidylcholine (DMPC-DSPC) lipid bilayers....... The lipid bilayers are mica-supported double bilayers in which ripple-phase formation occurs in the top bilayer. In one-component DPPC lipid bilayers, the stable and metastable ripple phases were observed. In addition, a third ripple structure with approximately twice the wavelength of the metastable...... ripples was seen. From height profiles of the AFM images, estimates of the amplitudes of the different ripple phases are reported. To elucidate the processes of ripple formation and disappearance, a ripple-phase DPPC lipid bilayer was taken through the pretransition in the cooling and the heating...

  16. Coherent quantum phase slip in two-component bosonic atomtronic circuits

    International Nuclear Information System (INIS)

    Gallemí, A; Mateo, A Muñoz; Mayol, R; Guilleumas, M

    2016-01-01

    Coherent quantum phase slip consists in the coherent transfer of vortices in superfluids. We investigate this phenomenon in two miscible coherently coupled components of a spinor Bose gas confined in a toroidal trap. After imprinting different vortex states, i.e. states with quantized circulation, on each component, we demonstrate that during the whole dynamics the system remains in a linear superposition of two current states in spite of the nonlinearity, and can be mapped onto a linear Josephson problem. We propose this system as a good candidate for the realization of a Mooij–Harmans qubit and remark its feasibility for implementation in current experiments with 87 Rb, since we have used values for the physical parameters currently available in laboratories. (paper)

  17. Phase Doppler anemometry as an ejecta diagnostic

    Science.gov (United States)

    Bell, D. J.; Chapman, D. J.

    2017-01-01

    When a shock wave is incident on a free surface, micron sized pieces of the material can be ejected from that surface. Phase Doppler Anemometry (PDA) is being developed to simultaneously measure the sizes and velocities of the individual shock induced ejecta particles; providing an important insight into ejecta phenomena. The results from experiments performed on the 13 mm bore light gas gun at the Institute of Shock Physics, Imperial College London are presented. Specially grooved tin targets were shocked at pressures of up to 14 GPa, below the melt on release pressure, to generate ejecta particles. These experiments are the first time that PDA has been successfully fielded on dynamic ejecta experiments. The results and current state of the art of the technique are discussed along with the future improvements required to optimise performance and increase usability.

  18. Numerical stud of glare spot phase Doppler anemometry

    OpenAIRE

    Hespel , Camille; Ren , Kuan Fang; Gréhan , Gérard; Onofri , Fabrice

    2008-01-01

    International audience; The phase Doppler anemometry has (PDA) been developed to measure simultaneously the velocity and the size of droplets. When the concentration of particles is high, tightly focused beams must be used, as in the dual burst PDA. The latter permits an access to the refractive index of the particle, but the effect of wave front curvature of the incident beams becomes evident. In this paper, we introduce a glare spot phase Doppler anemometry which uses two large beams. The i...

  19. Laser Doppler measurements in two-phase flows

    International Nuclear Information System (INIS)

    Durst, F.; Zare, M.

    1976-01-01

    Basic theory for laser-Doppler velocity measurements of large reflecting or refracting surfaces is provided. It is shown that the Doppler-signals contain information of the velocity and size of the large bodies, and relationships for transforming velocity and radius of curvature of moving spheres are presented. Preliminary experiments verified the analytical findings and demonstrated the applicability of the method to some two-phase flows

  20. Measurement of cylindrical particles with phase Doppler anemometry.

    Science.gov (United States)

    Mignon, H; Gréhan, G; Gouesbet, G; Xu, T H; Tropea, C

    1996-09-01

    Light scattering from cylindrical particles has been described with geometric optics. The feasibility of determining the particle diameter with a planar phase Doppler anemometer has been examined by simulations and experiments. In particular, the influence of particle orientation on measurability and measurement accuracy has been investigated. Some recommendations for realizing a practical-measurement instrument have been presented.

  1. Computer analysis of an adiabatic Stirling cryocooler using a two-phase two-component working fluid

    International Nuclear Information System (INIS)

    Renfroe, D.A.; Cheung, C.M.

    1992-01-01

    This paper describes the performance and behavior of a Stirling cyrocooler incorporating a working fluid composed of helium and nitrogen. At the operating temperature of the cryocooler (80 K), the nitrogen component will condense in the freezer section. It is shown that the phase change in the working fluid increased the heat lifted for a given size and weight of machine and the coefficient of performance. The magnitude of these effects was dependent on the mass ratio of nitrogen to helium, phase angle between the compression and expansion processes, and the ratio of the compression space volume to the expansion space volume. The optimum heat lifted performance was obtained for a mass ratio of four parts of nitrogen to one part of helium, a phase angle of approximately 100 degrees, and a volume ratio of two which resulted in a heat lifted increase of 75% over the single phase, 90 degree phase angle configuration. The coefficient of performance showed a 20% improvement

  2. Nanoscale characteristics of triacylglycerol oils: phase separation and binding energies of two-component oils to crystalline nanoplatelets.

    Science.gov (United States)

    MacDougall, Colin J; Razul, M Shajahan; Papp-Szabo, Erzsebet; Peyronel, Fernanda; Hanna, Charles B; Marangoni, Alejandro G; Pink, David A

    2012-01-01

    Fats are elastoplastic materials with a defined yield stress and flow behavior and the plasticity of a fat is central to its functionality. This plasticity is given by a complex tribological interplay between a crystalline phase structured as crystalline nanoplatelets (CNPs) and nanoplatelet aggregates and the liquid oil phase. Oil can be trapped within microscopic pores within the fat crystal network by capillary action, but it is believed that a significant amount of oil can be trapped by adsorption onto crystalline surfaces. This, however, remains to be proven. Further, the structural basis for the solid-liquid interaction remains a mystery. In this work, we demonstrate that the triglyceride liquid structure plays a key role in oil binding and that this binding could potentially be modulated by judicious engineering of liquid triglyceride structure. The enhancement of oil binding is central to many current developments in this area since an improvement in the health characteristics of fat and fat-structured food products entails a reduction in the amount of crystalline triacylglycerols (TAGs) and a relative increase in the amount of liquid TAGs. Excessive amounts of unbound, free oil, will lead to losses in functionality of this important food component. Engineering fats for enhanced oil binding capacity is thus central to the design of more healthy food products. To begin to address this, we modelled the interaction of triacylglycerol oils, triolein (OOO), 1,2-olein elaidin (OOE) and 1,2-elaidin olein (EEO) with a model crystalline nanoplatelet composed of tristearin in an undefined polymorphic form. The surface of the CNP in contact with the oil was assumed to be planar. We considered pure OOO and mixtures of OOO + OOE and OOO + EEO with 80% OOO. The last two cases were taken as approximations to high oleic sunflower oil (HOSO). The intent was to investigate whether phase separation on a nanoscale took place. We defined an "oil binding capacity" parameter, B

  3. Laser doppler anemometry in single- and two-phase flows

    International Nuclear Information System (INIS)

    Durst, F.

    1976-01-01

    The present report gives an introduction into laser-Doppler anemometry and tries to explain the basic physical principles of this measuring technique. Moire fringe patterns are used in order to visually model LDA-signals and to explain the basic difference in optical systems. It is pointed out that LDA measurements in highly turbulent flows and in two-phase flows should be attempted with direction sensitive instruments only. Some of the optical systems developed by the author and his collaborators are introduced and their functioning in measurements is demonstrated. These measurements embrace investigations in a number of single-phase flows including flames. (orig.) [de

  4. A Wearable Transcranial Doppler Ultrasound Phased Array System.

    Science.gov (United States)

    Pietrangelo, Sabino J; Lee, Hae-Seung; Sodini, Charles G

    2018-01-01

     Practical deficiencies related to conventional transcranial Doppler (TCD) sonography have restricted its use and applicability. This work seeks to mitigate several such constraints through the development of a wearable, electronically steered TCD velocimetry system, which enables noninvasive measurement of cerebral blood flow velocity (CBFV) for monitoring applications with limited operator interaction. A highly-compact, discrete prototype system was designed and experimentally validated through flow phantom and preliminary human subject testing. The prototype system incorporates a custom two-dimensional transducer array and multi-channel transceiver electronics, thereby facilitating acoustic beamformation via phased array operation. Electronic steering of acoustic energy enables algorithmic system controls to map Doppler power throughout the tissue volume of interest and localize regions of maximal flow. Multi-focal reception permits dynamic vessel position tracking and simultaneous flow velocimetry over the time-course of monitoring. Experimental flow phantom testing yielded high correlation with concurrent flowmeter recordings across the expected range of physiological flow velocities. Doppler power mapping has been validated in both flow phantom and preliminary human subject testing, resulting in average vessel location mapping times testing. A wearable prototype CBFV measurement system capable of autonomous vessel search and tracking has been presented. Although flow phantom and preliminary human validation show promise, further human subject testing is necessary to compare velocimetry data against existing commercial TCD systems. Additional human subject testing must also verify acceptable vessel search and tracking performance under a variety of subject populations and motion dynamics-such as head movement and ambulation.

  5. Determination of Bisphenol A and Bisphenol AF in Vinegar samples by two-component mixed ionic liquid dispersive liquid-phase microextraction coupled with high performance liquid chromatography

    International Nuclear Information System (INIS)

    Tai, Z.; Liu, M.; Hu, X.; Yang, Y.

    2014-01-01

    This paper describes a sensitive and simple method for the determination of bisphenol A (BPA) and bisphenol AF (BPAF) in vinegar samples using two-component mixed ionic liquid dispersive liquid-phase microextraction coupled with high performance liquid chromatography. In this work, BPA and BPAF were selected as the model analytes, and two-component mixed ionic liquid included 1-butyl-3-methylimidazolium hexafluorophosphate ((C4Mim)PF6) and 1-hexyl-3-methyl-imidazolium hexafluorophosphate ((C6Mim)PF6) was used as the extraction solvent for the first time here. Parameters that affect the extraction efficiency were investigated. Under the optimum conditions, good linear relationships were discovered in the range of 1.0-100 micro g/L for BPA and 2.0-150 micro g/L for BPAF, respectively. Detection limits of proposed method based on the signal-to-noise ratio (S/N=3) were in the range of 0.15-0.38 micro g/L. The efficiencies of proposed method have also been demonstrated with spiked real vinegar samples. The result show this method/ procedure to be a more efficient approach for the determination of BPA and BPAF in real vinegar, presenting average recovery rate of 89.3-112 % and precision values of 0.9-13.5% (RSDs, n = 6). In comparison with traditional solid phase extraction procedures this method results in lower solvent consumption, low pollution levels, and faster sample preparation. (author)

  6. Numerical study of glare spot phase Doppler anemometry

    Science.gov (United States)

    Hespel, C.; Ren, K. F.; Gréhan, G.; Onofri, F.

    2008-03-01

    The phase Doppler anemometry has (PDA) been developed to measure simultaneously the velocity and the size of droplets. When the concentration of particles is high, tightly focused beams must be used, as in the dual burst PDA. The latter permits an access to the refractive index of the particle, but the effect of wave front curvature of the incident beams becomes evident. In this paper, we introduce a glare spot phase Doppler anemometry which uses two large beams. The images of the particle formed by the reflected and refracted light, known as glare spots, are separated in space. When a particle passes through the probe volume, the two parts in a signal obtained by a detector in forward direction are then separated in time. If two detectors are used the phase differences and the intensity ratios between two signals, the distance between the reflected and refracted spots can be obtained. These measured values provide information about the particle diameter and its refractive index, as well as its two velocity components. This paper is devoted to the numerical study of such a configuration with two theoretical models: geometrical optics and rigorous electromagnetism solution.

  7. Survey of studies on the flow and heat transfer of two-component, two-phase flow of liquid metal in magnetic field

    International Nuclear Information System (INIS)

    Kumamaru, Hiroshige

    1980-01-01

    Brief review of the studies on the flow and heat transfer of two-component, two-phase flow of liquid metal in magnetic field is presented. R.J. Thome measured the distribution of void rate, slip ratio and pressure loss for the two-phase flow of NaK-N 2 under vertical magnetic field. The void rate distribution became even and the slip ratio increased with the increasing magnetic field. The experimental results of pressure loss was compared with the calculation by an equation derived from the homogeneous flow model. R.G. Owen et al. made the analytical studies of the MHD friction loss of two phase flow. Michiyoshi et al. made experimental studies on the hydrodynamic local properties of Hg-Ar two-phase flow of slug region in a vertically ascending tube under magnetic field, and Kimi et al. also made studies on the heat transfer of Hg-Ar flow under magnetic field. Saito et al. measured the slip ratio and pressure loss of NaK-N 2 flow. As a whole, it can be said that the average void rate decreases, and its distribution becomes even under magnetic field. The slip ratio increases, and the friction loss factor becomes nearly one. It was hard to make clear the heat transfer characteristics. (Kato, T.)

  8. Orthogonality Catastrophe as a prerequisite for the irreversible decay of the global relative phase of a two-component Bose-Einstein condensate

    Science.gov (United States)

    Birman, Joseph L.; Kuklov, A. B.

    2001-05-01

    The concept of the orthogonality catastrophe (OC), which has been introduced previously for one component condensate ( A.B. Kuklov, J.L. Birman, PRA 63), 013609 (2001), is applied to the two-component condensate. The evolution of the global relative phase, which is created by the rf-pulse, is studied under the condition of no exchange of bosons between the components after the pulse. It is shown that the normal component does not induce the OC. Instead, it produces a reversible thermal dephasing, which competes with the quantum phase diffusion (QPD) effect (E.M.Wright, et al, PRL 77), 2158(1996). The thermal dephasing results from the thermal ensemble averaging, and the corresponding dephasing rate is controlled by the two-body interaction and temperature as well as by the closeness to the intrinsic su(2) symmetry, so that no dephasing exists in the case of the exact symmetry (A.B. Kuklov, J.L. Birman, PRL 85), 5488 (2000). The reversible nature of the thermal dephasing as well as of the QPD can be revealed in the atomic echo effect. The role of external noise in erasing the phase memory is discussed as well.

  9. A phased array antenna for Doppler reflectometry in ASDEX upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Wolf, Stefan; Lechte, Carsten; Kasparek, Walter [IGVP, Universitaet Stuttgart, D-70569 Stuttgart (Germany); Hennequin, Pascale [Laboratoire de Physique des Plasmas, CNRS, Ecole Polytech., F-91128 Palaiseau (France); Conway, Garrard; Happel, Tim [Max-Planck-Institut fuer Plasmaphysik, D-85748 Garching (Germany); Collaboration: ASDEX Upgrade Team

    2016-07-01

    In a toroidal plasma, Doppler reflectometry (DR) allows investigating electron density fluctuations with finite k {sub perpendicular} {sub to}. The injected microwave beam's frequency determines the radial position of the probed region, its tilt angle selects the wavenumber satisfying the Bragg condition for backscattering. The rotation velocity can be calculated from the Doppler shift of the backscattered signal's frequency. By varying the injected frequency, radial profiles can be reconstructed. Varying the tilt angle resolves the k {sub perpendicular} {sub to} -spectrum of the fluctuations. For DR, a pair of phased array antennas (PAAs) has been designed, built, and installed in the ASDEX Upgrade tokamak. Beam steering is done by slightly changing the injected frequency, thus, the PAAs do not need any movable parts or electronics inside the vacuum vessel. From 75 to 105 GHz, the PAAs feature 13 frequency bands, each with an angular scan range of -20 to +20 {sup circle}. So, for each angle, there are 13 radial positions to be probed. The results from PAA characterisation, commissioning, and first DR measurements are presented.

  10. Dispersed single-phase-step Michelson interferometer for Doppler imaging using sunlight.

    Science.gov (United States)

    Wan, Xiaoke; Ge, Jian

    2012-09-15

    A Michelson interferometer is dispersed with a fiber array-fed spectrograph, providing 59 Doppler sensing channels using sunlight in the 510-570 nm wavelength region. The interferometer operates at a single-phase-step mode, which is particularly advantageous in multiplexing and data processing compared to the phase-stepping mode of other interferometer spectrometer instruments. Spectral templates are prepared using a standard solar spectrum and simulated interferometer modulations, such that the correlation function with a measured 1D spectrum determines the Doppler shift. Doppler imaging of a rotating cylinder is demonstrated. The average Doppler sensitivity is ~12 m/s, with some channels reaching ~5 m/s.

  11. Two-component dressed-bag model for NN interaction: deuteron structure and phase shifts up to 1 GeV

    International Nuclear Information System (INIS)

    Kukulin, V.I.; Obukhovsky, I.T.; Pomerantsev, V.N.; Faessler, A.

    2002-01-01

    A two-component model is developed for the intermediate-range NN interaction based on a new mechanism with an intermediate symmetric six-quark bag 'dressed' by σ and other fields. To calculate the transition amplitude, the microscopic six-quark shell-model in combination with the 3 P 0 -quark pion production mechanism is used. As a result, an effective energy-dependent NN interaction is constructed. The new quark-meson model for the NN interaction has been demonstrated to result in a new type of NN tensor force at intermediate ranges, which is crucially important for the treatment of tensor mixing at intermediate energies. The suggested model is able to describe NN phase shifts in a broad energy range from low energy up to 1 GeV, and the deuteron structure. The generalization of the model results in new spin-orbit 2N and 3N forces and new meson-exchange currents induced by intermediate dressed bag components, and also in the enhancement of a collective σ-field in nuclei. (author)

  12. Comparison of different configurations of Phase Doppler Analyser

    Directory of Open Access Journals (Sweden)

    Zaremba Matouš

    2016-01-01

    Full Text Available A phase Doppler anemometry (PDA technique is widely used in experimental fluid mechanics to measure size and velocity of particles in the fluid flow. Even though this method is common in experimental fluid mechanics, there are only few techniques that might serve for the purpose of the evaluation of the PDA system. To examine results of the PDA visualizations techniques are usually used. However, this approach suffers from several aspects. Mainly, it is difficult to determine the exact position of the measurement volume of PDA system. Then it is complicated to determine which particles are passing through the measuring volume. Another way how to examine performance of the PDA system is to use two PDA systems simultaneously. By using one laser for both systems we can avoid previously mentioned aspects. In our experiments, we use fiber based PDA system and classical PDA system both made by Dantec Dynamics. The aim of this paper is to compare results from various configurations and highlight crucial parameters that influence measurements.

  13. Comparison of different configurations of Phase Doppler Analyser

    Science.gov (United States)

    Zaremba, Matouš; Malý, Milan; Jedelský, Jan; Jícha, Miroslav

    2016-03-01

    A phase Doppler anemometry (PDA) technique is widely used in experimental fluid mechanics to measure size and velocity of particles in the fluid flow. Even though this method is common in experimental fluid mechanics, there are only few techniques that might serve for the purpose of the evaluation of the PDA system. To examine results of the PDA visualizations techniques are usually used. However, this approach suffers from several aspects. Mainly, it is difficult to determine the exact position of the measurement volume of PDA system. Then it is complicated to determine which particles are passing through the measuring volume. Another way how to examine performance of the PDA system is to use two PDA systems simultaneously. By using one laser for both systems we can avoid previously mentioned aspects. In our experiments, we use fiber based PDA system and classical PDA system both made by Dantec Dynamics. The aim of this paper is to compare results from various configurations and highlight crucial parameters that influence measurements.

  14. Structure of a swirl-stabilized spray flame by imaging, laser Doppler velocimetry, and phase Doppler anemometry

    Science.gov (United States)

    Edwards, C. F.; Rudoff, R. C.

    1991-01-01

    Data are presented which describe the mean structure of a steady, swirl-stabilized, kerosene spray flame in the near-injector region of a research furnace. The data presented include ensemble-averaged results of schlieren, luminosity, and extinction imaging, measurement of the gas phase velocity field by laser Doppler velocimetry, and characterization of the condensed phase velocity by phase Doppler anemometry. The results of these studies define six key regions in the flame: the dense spray region; the rich, two-phase, fuel jet; the main air jet; the internal product recirculation zone; the external product recirculation zone; and the gaseous diffusion flame zone. The first five of these regions form a conical mixing layer which prepares the air and fuel for combustion. The air and fuel jets comprise the central portion of this mixing layer and are bounded on either side by the hot product gases of the internal and external recirculation zones. Entrainment of these product gases into the air/fuel streams provides the energy required to evaporate the fuel spray and initiate combustion. Intermittency of the internal recirculation and spray jet flows accounts for unexpected behavior observed in the aerodynamics of the two phases. The data reported herein are part of the database being accumulated on this spray flame for the purpose of detailed comparison with numerical modeling.

  15. Measurement of phase interaction in dispersed gas-particle two-phase flow by phase-doppler anemometry

    OpenAIRE

    Mergheni Ali Mohamed; Ben Ticha Hmaied; Sautet Jen-Charles; Godard Gille; Ben Nasrallah Sassi

    2008-01-01

    For simultaneous measurement of size and velocity distributions of continuous and dispersed phases in a two-phase flow a technique phase-Doppler anemometry was used. Spherical glass particles with a particle diameter range from 102 up to 212 µm were used. In this two-phase flow an experimental results are presented which indicate a significant influence of the solid particles on the flow characteristics. The height of influence of these effects depends on the local position in the jet. Near t...

  16. Application of coincidence Doppler-broadening spectroscopy to different carbon phases

    International Nuclear Information System (INIS)

    Ito, Y.; Djourelov, N.; Suzuki, T.; Kondo, K.; Ito, Y.; Shantarovich, V.; Onoe, J.

    2004-01-01

    Coincidence Doppler-broadening spectroscopy was applied to C60 and C70 fullerenes and other carbon phases, such as nanotubes and graphites. Remarkable differences were observed in the Doppler-broadening of the positron annihilation γ-rays in these materials, which reflect the different densities distribution of the momentum for electrons annihilated with positrons. This would be caused by the different composition of the π and σ electrons in annihilation with positrons. This result shows the sensitivity of the coincidence Doppler-broadening method to determine the density distribution of electrons sampled by positrons. (orig.)

  17. Power spectral density of velocity fluctuations estimated from phase Doppler data

    OpenAIRE

    Jicha Miroslav; Lizal Frantisek; Jedelsky Jan

    2012-01-01

    Laser Doppler Anemometry (LDA) and its modifications such as PhaseDoppler Particle Anemometry (P/DPA) is point-wise method for optical nonintrusive measurement of particle velocity with high data rate. Conversion of the LDA velocity data from temporal to frequency domain – calculation of power spectral density (PSD) of velocity fluctuations, is a non trivial task due to nonequidistant data sampling in time. We briefly discuss possibilities for the PSD estimation and specify limitations caused...

  18. Measurement of phase interaction in dispersed gas-particle two-phase flow by phase-doppler anemometry

    Directory of Open Access Journals (Sweden)

    Mergheni Ali Mohamed

    2008-01-01

    Full Text Available For simultaneous measurement of size and velocity distributions of continuous and dispersed phases in a two-phase flow a technique phase-Doppler anemometry was used. Spherical glass particles with a particle diameter range from 102 up to 212 µm were used. In this two-phase flow an experimental results are presented which indicate a significant influence of the solid particles on the flow characteristics. The height of influence of these effects depends on the local position in the jet. Near the nozzle exit high gas velocity gradients exist and therefore high turbulence production in the shear layer of the jet is observed. Here the turbulence intensity in the two-phase jet is decreased compared to the single-phase jet. In the developed zone the velocity gradient in the shear layer is lower and the turbulence intensity reduction is higher. .

  19. Superimposed noninterfering probes to extend the capabilities of phase Doppler anemometry.

    Science.gov (United States)

    Onofri, Fabrice; Lenoble, Anne; Radev, Stefan

    2002-06-20

    We propose using multiple superimposed noninterfering probes (SNIPs) of the same wavelength but different beam angles to extend the capabilities of phase Doppler anemometry. When a particle is moving in a SNIP the Doppler signals that are produced exhibit multiple Doppler frequencies and phase shifts. The resolution of the measurements of particle size (i.e., by fringe spacing and Doppler frequency) increases with beam angle. Then, with the solution proposed, even with only two detectors several measurements of size can be obtained for the same particle with increasing resolution if we consider higher frequencies in the signal. Several optical solutions to produce SNIPs as well as a signal-processing algorithm to treat the multiple-frequency Doppler signals are proposed. Experimental validations of the sizing of spherical and cylindrical particles demonstrate the applicability of this technique for particle measurement. We believe that this new technique can be of great interest when high resolution of size, velocity, and even refractive index is required.

  20. Thermodynamique de l'écoulement diphasique compressible à deux constituants de Fanno Thermodynamic of Two-Phase Two Component Compressible Fanno Type Flow

    Directory of Open Access Journals (Sweden)

    Attou A.

    2006-12-01

    Full Text Available Le comportement d'un fluide diphasique gaz-liquide lors d'un écoulement adiabatique à travers une conduite de section constante est étudié, dans cet article, du point de vue thermodynamique. En admettant le mélange diphasique homogène, le traitement des lois physiques de conservation permet de déduire analytiquement l'équation d'évolution du fluide et la manière dont celle-ci s'écarte de l'évolution isotherme. Sur les bases de la forme différentielle de cette équation et du second principe de la thermodynamique, les propriétés de cet écoulement sont discutées. La détermination de la limite de Fanno a permis de mettre en évidence l'existence d'une longueur maximale de conduite au-delà de laquelle l'écoulement considéré n'est plus possible. Cette longueur maximale est fonction du titre massique et des conditions initiales, c'est-à-dire les variables d'état et la vitesse à l'entrée. La cohérence des résultats est vérifiée en appliquant systématiquement ceux-ci à l'écoulement d'un gaz parfait. Cette théorie permet de comprendre et de justifier l'existence d'états d'écoulement dits multicritiques pour lesquels un formalisme physique est proposé. Elle est appliquée à des écoulements diphasiques à travers les circuits de décharge comportant des singularités géométriques telles que des élargissements brusques. Le présent modèle, basé sur le formalisme proposé pour la multicriticité, est validé au moyen de données expérimentales obtenues pour des relâchements quasi stationnaires d'azote pur et de mélange eau-azote à travers une ligne de décharge complexe comportant plusieurs élargissements brusques en cascade. Prédites par le modèle, la configuration critique et les valeurs du débit maximum et des variables de l'écoulement (pression et température à travers la ligne de décharge s'accordent avec succès avec les résultats expérimentaux. The behaviour of an adiabatic two-phase gas

  1. Investigation of two-phase bubbly flows using laser doppler anemometry

    OpenAIRE

    Marié , Jean-Louis

    1983-01-01

    International audience; The present work is devoted to the development of an accurate and reliable laser Doppler anemometer technique (L.D.A.) meant for the measurement of the characteristics of twoephase bubbly flows. Most of these characteristics are the various statistical moments of the velocity fluctuations and the Reynolds stress tensor components within the continuous phase but also, under well defined conditions, the mean slip velocity of the dispersed phase. Although this technique w...

  2. Solitary waves of surface plasmon polariton via phase shifts under Doppler broadening and Kerr nonlinearity

    Science.gov (United States)

    Ahmad, S.; Ahmad, A.; Bacha, B. A.; Khan, A. A.; Abdul Jabar, M. S.

    2017-12-01

    Surface Plasmon Polaritons (SPPs) are theoretically investigated at the interface of a dielectric metal and gold. The output pulse from the dielectric is used as the input pulse for the generation of SPPs. The SPPs show soliton-like behavior at the interface. The solitary form of a SPP is maintained under the effects of Kerr nonlinearity, Doppler broadening and Fresnel dragging whereas its phase shift is significantly modified. A 0.3radian phase shift is calculated in the presence of both Kerr nonlinearity and Fresnel dragging in the absence of plasma motion. The phase shift is enhanced to 60radian due to the combined effect of Doppler broadening, Kerr nonlinearity and Fresnel dragging. The results may have significant applications in nano-photonics, optical tweezers, photovoltaic devices, plasmonster and sensing technology.

  3. New phase method of measuring particle size with laser Doppler radar

    Science.gov (United States)

    Zemlianskii, Vladimir M.

    1996-06-01

    A vast field of non-contact metrology, vibrometry, dynamics and microdynamics problems solved on the basis of laser Doppler method resulted in the development of great variety of laser Doppler radar (LDR). In coherent LDR few beams with various polarization are generally adopted, that are directed at the zone of measurement, through which the probing air stream moves. Studies of various coherent LDR demonstrated that polarization-phase effects of scattering can in some cases considerably effect on the signal-to-noise ratio of the Doppler signal. On the other side using phase effects can simultaneous measurement of size and velocity of spherical particles. New possibilities for improving the accuracy of measuring spherical particles' sizes come to light when application is made in coherent LDR of two waves- probing and one out of the types of symmetrical reception of scattered radiation, during which phase-conjugate signals are formed. The theoretical analysis on the basis of the scattering theory showed, that in symmetrical reception of scattered radiation with respect to the planes OXZ and OYZ output signal of the photoreceiver contains two high- frequency signal components, which in relation to parameters of the probing and size, can either be in phase or antiphase. Results of numerical modeling are presented: amplitude of high frequency signal, coefficient of phase and polarization matching of mixed waves, the depths of photocurrent modulation and also signal's phase in relation to the angle between the probing beams. Phase method of determining particle's sizes based on the use of two wavelengths probing and symmetrical reception of scattered radiation in which conditions for the formation of phase conjugated high-frequency signals are satisfied is presented.

  4. Effect of net surface charge on particle sizing and material recognition by using phase Doppler anemometry

    International Nuclear Information System (INIS)

    Zhou Jun; Xie Li

    2011-01-01

    By taking net surface charge into consideration, the scattering field of particles illuminated by dual laser beams of phase Doppler anemometry (PDA) is computed based on Mie's theory, and the effect of net surface charge on the phase-diameter relationship and the phase ratio is studied. It is found that the phase-diameter relationship and the relationship between the phase ratio and the refractive index of charged particles could be significantly different from those of uncharged particles, which would lead to errors in particle sizing and the measurement of refractive indices. A method of recognizing charged particles and determining the value of their surface conductivity, which is related to net surface charge, is proposed by utilizing the effect of net surface charge on the measurement of refractive indices using PDA.

  5. Effect of net surface charge on particle sizing and material recognition by using phase Doppler anemometry

    Energy Technology Data Exchange (ETDEWEB)

    Zhou Jun; Xie Li

    2011-01-20

    By taking net surface charge into consideration, the scattering field of particles illuminated by dual laser beams of phase Doppler anemometry (PDA) is computed based on Mie's theory, and the effect of net surface charge on the phase-diameter relationship and the phase ratio is studied. It is found that the phase-diameter relationship and the relationship between the phase ratio and the refractive index of charged particles could be significantly different from those of uncharged particles, which would lead to errors in particle sizing and the measurement of refractive indices. A method of recognizing charged particles and determining the value of their surface conductivity, which is related to net surface charge, is proposed by utilizing the effect of net surface charge on the measurement of refractive indices using PDA.

  6. Primordial two-component maximally symmetric inflation

    Science.gov (United States)

    Enqvist, K.; Nanopoulos, D. V.; Quirós, M.; Kounnas, C.

    1985-12-01

    We propose a two-component inflation model, based on maximally symmetric supergravity, where the scales of reheating and the inflation potential at the origin are decoupled. This is possible because of the second-order phase transition from SU(5) to SU(3)×SU(2)×U(1) that takes place when φ≅φcinflation at the global minimum, and leads to a reheating temperature TR≅(1015-1016) GeV. This makes it possible to generate baryon asymmetry in the conventional way without any conflict with experimental data on proton lifetime. The mass of the gravitinos is m3/2≅1012 GeV, thus avoiding the gravitino problem. Monopoles are diluted by residual inflation in the broken phase below the cosmological bounds if φcUSA.

  7. Spin-excited oscillations in two-component fermion condensates

    International Nuclear Information System (INIS)

    Maruyama, Tomoyuki; Bertsch, George F.

    2006-01-01

    We investigate collective spin excitations in two-component fermion condensates with special consideration of unequal populations of the two components. The frequencies of monopole and dipole modes are calculated using Thomas-Fermi theory and the scaling approximation. As the fermion-fermion coupling is varied, the system shows various phases of the spin configuration. We demonstrate that spin oscillations have more sensitivity to the spin phase structures than the density oscillations

  8. Assessment of the Influence Factors on Nasal Spray Droplet Velocity Using Phase-Doppler Anemometry (PDA)

    OpenAIRE

    Liu, Xiaofei; Doub, William H.; Guo, Changning

    2011-01-01

    Droplet velocity is an important parameter that can be used to characterize nasal spray products. In this study, a phase-Doppler anemometry (PDA) system was used to measure the droplet velocities of nasal sprays. A survey of seven commercial nasal spray products showed a range of droplet velocities from 6.7 to 19.2 m/s, all significantly different from each other. A three-level, four-factor Box–Behnken design of experiments (DOE) methodology were applied to investigate the influences of actua...

  9. Iterative inversion of phase-Doppler-anemometry size distributions from sprays of optically inhomogeneous liquids.

    Science.gov (United States)

    Köser, O; Wriedt, T

    1996-05-20

    Using phase Doppler anemometry (PDA) to investigate sprays of optically inhomogeneous liquids leads to blurred measured size distributions. The blurring function is formed by performance of PDA measurements on single-size droplets generated by a piezoelectric droplet generator. To obtain the undistorted droplet-size distributions, a constrained iterative inversion algorithm is applied. The number of iteration steps to achieve the best possible restoration is determined by the use of synthetically generated data that has noise properties similar to the measured histograms. The obtained size distributions are checked by comparison with undistorted measurement results of an atomized optical homogeneous liquid.

  10. Experimental investigation of turbulence modulation in particle-laden coaxial jets by Phase Doppler Anemometry

    Energy Technology Data Exchange (ETDEWEB)

    Mergheni, M.A. [CORIA UMR 6614 CNRS, Universite et INSA de ROUEN, Avenue de l' Universite, BP 12, 76801 Saint Etienne du Rouvray, Cedex (France)]|[LESTE Ecole Nationale d' Ingenieurs de Monastir, 5019 Monastir (Tunisia); Sautet, J.C.; Godard, G. [CORIA UMR 6614 CNRS, Universite et INSA de ROUEN, Avenue de l' Universite, BP 12, 76801 Saint Etienne du Rouvray, Cedex (France); Ben Ticha, H.; Ben Nasrallah, S. [LESTE Ecole Nationale d' Ingenieurs de Monastir, 5019 Monastir (Tunisia)

    2009-03-15

    The effect of solid particles on the flow characteristics of axisymmetric turbulent coaxial jets for two flow conditions was studied. Simultaneous measurements of size and velocity distributions of continuous and dispersed phases in a two-phase flow are presented using a Phase Doppler Anemometry (PDA) technique. Spherical glass particles with a particle diameter range from 102 to 212 {mu}m were used in this two-phase flow, the experimental results indicate a significant influence of the solid particles and the Re on the flow characteristics. The data show that the gas phase has lower mean velocity in the near-injector region and a higher mean velocity at the developed region. Near the injector at low Reynolds number (Re = 2839) the presence of the particles dampens the gas-phase turbulence, while at higher Reynolds number (Re = 11 893) the gas-phase turbulence and the velocity fluctuation of particle-laden jets are increased. The particle velocity at higher Reynolds number (Re = 11 893) and is lower at lower Reynolds number (Re = 2839). The slip velocity between particles and gas phase existed over the flow domain was examined. More importantly, the present experiment results suggest that, consideration of the gas characteristic length scales is insufficient to predict gas-phase turbulence modulation in gas-particle flows. (author)

  11. Development of a two-phase, two-component jet pump refrigerator for utilization of low-temperature solar heat. Final report; Entwicklung einer Zweiphasen-/Zweikomponenten-Strahlpumpenkaelteanlage zur Nutzung solarer Niedertemperaturwaerme. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Mostofizadeh, C.; Bohne, D.

    2001-08-01

    A solar refrigerator for air conditioning and cooling was developed. The key component is a two-phase, two-component jet pump with ammonia and water as working fluid. Both the pump flow and the suction flow can be two-phase flows. This way, the advantages of both the absorption and the compression principle will be utilized, and a compact size will be achieved. Upon termination of the calculations, the function of the pump will be investigated in a 0 W pilot plant. For this, various geometries were calculated and tested for their potential efficiencies. A prototype will be constructed on the basis of the results. [German] Das Ziel des Vorhabens besteht in der Entwicklung einer solarbetriebenen Kaelteanlage fuer Klimatisierungs- und Kuehlungszwecke. Die Hauptkomponente der Kaelteanlage ist eine Zweiphasen-/Zweikomponenten-Strahlpumpe, die mit dem Arbeitsgemisch Ammoniak/Wasser betrieben wird. Sowohl der Treib- als auch der Saugstrom koennen zweiphasig sein. Dadurch sollen einerseits die Vorteile des Absorptions- und des Kompressionsprinzips miteinander verknuepft und andererseits ein kompakter Aufbau erreicht werden. Nach Abschluss der thermodynamischen und kinetischen Berechnungen soll die Funktion der Zweiphasen-/Zweikomponenten-Strahlpumpe mit Hilfe einer Pilotanlage mit ca. 20 kW Kaelteleistung untersucht werden. Dazu werden nach Vorausberechnungen verschiedene Geometrien in Bezug auf erzielbare Wirkungsgrade getestet. Die Ergebnisse bilden die Basis fuer den Bau eines Prototyps. (orig.)

  12. Influence of internal refractive index gradients on size measurements of spherically symmetric particles by phase Doppler anemometry.

    Science.gov (United States)

    Schneider, M; Hirleman, E D

    1994-04-20

    A model based on geometric optics for predicting the response of interferometric (phase Doppler) instruments for size measurements of particles with radially symmetric but inhomogeneous internal refractive index profiles is developed. The model and results are important for applications in which heat or mass transfer from the particles or droplets is significant, for example, in liquid-fuel combustion. To quantify the magnitude of potential bias errors introduced by the classical assumption of uniform internal properties on phase Doppler measurements, we compute calibration curves for a sequence of times during the evaporation of a decane droplet immersed in an environment of T = 2000 K and p = 10 bars. The results reveal considerable effects on the relation between phase difference and droplet diameter caused by the refractive index gradients present. The model provides an important tool to assess sizing uncertainties that can be expected when applying conventional (based on uniform properties) phase Doppler calibration curves in spray combustion and similar processes.

  13. Power spectral density of velocity fluctuations estimated from phase Doppler data

    Science.gov (United States)

    Jedelsky, Jan; Lizal, Frantisek; Jicha, Miroslav

    2012-04-01

    Laser Doppler Anemometry (LDA) and its modifications such as PhaseDoppler Particle Anemometry (P/DPA) is point-wise method for optical nonintrusive measurement of particle velocity with high data rate. Conversion of the LDA velocity data from temporal to frequency domain - calculation of power spectral density (PSD) of velocity fluctuations, is a non trivial task due to nonequidistant data sampling in time. We briefly discuss possibilities for the PSD estimation and specify limitations caused by seeding density and other factors of the flow and LDA setup. Arbitrary results of LDA measurements are compared with corresponding Hot Wire Anemometry (HWA) data in the frequency domain. Slot correlation (SC) method implemented in software program Kern by Nobach (2006) is used for the PSD estimation. Influence of several input parameters on resulting PSDs is described. Optimum setup of the software for our data of particle-laden air flow in realistic human airway model is documented. Typical character of the flow is described using PSD plots of velocity fluctuations with comments on specific properties of the flow. Some recommendations for improvements of future experiments to acquire better PSD results are given.

  14. Power spectral density of velocity fluctuations estimated from phase Doppler data

    Directory of Open Access Journals (Sweden)

    Jicha Miroslav

    2012-04-01

    Full Text Available Laser Doppler Anemometry (LDA and its modifications such as PhaseDoppler Particle Anemometry (P/DPA is point-wise method for optical nonintrusive measurement of particle velocity with high data rate. Conversion of the LDA velocity data from temporal to frequency domain – calculation of power spectral density (PSD of velocity fluctuations, is a non trivial task due to nonequidistant data sampling in time. We briefly discuss possibilities for the PSD estimation and specify limitations caused by seeding density and other factors of the flow and LDA setup. Arbitrary results of LDA measurements are compared with corresponding Hot Wire Anemometry (HWA data in the frequency domain. Slot correlation (SC method implemented in software program Kern by Nobach (2006 is used for the PSD estimation. Influence of several input parameters on resulting PSDs is described. Optimum setup of the software for our data of particle-laden air flow in realistic human airway model is documented. Typical character of the flow is described using PSD plots of velocity fluctuations with comments on specific properties of the flow. Some recommendations for improvements of future experiments to acquire better PSD results are given.

  15. Laser--Doppler anemometry technique applied to two-phase dispersed flows in a rectangular channel

    International Nuclear Information System (INIS)

    Lee, S.L.; Srinivasan, J.

    1979-01-01

    A new optical technique using Laser--Doppler anemometry has been applied to the local measurement of turbulent upward flow of a dilute water droplet--air two-phase dispersion in a vertical rectangular channel. Individually examined were over 20,000 droplet signals coming from each of a total of ten transversely placed measuring points, the closest of which to the channel wall was 250 μ away from the wall. Two flows of different patterns due to different imposed flow conditions were investigated, one with and the other without a liquid film formed on the channel wall. Reported are the size and number density distribution and the axial and lateral velocity distributions for the droplets as well as the axial and lateral velocity distributions for the air

  16. Mechanistic study on spraying of blended biodiesel using phase Doppler anemometry

    International Nuclear Information System (INIS)

    Kamrak, Juthamas; Kongsombut, Benjapol; Grehan, Gerard; Saengkaew, Sawitree; Kim, Kyo-Seon; Charinpanitkul, Tawatchai

    2009-01-01

    Droplet size and dynamics of blended palm oil-based fatty acid methyl ester (FAME) and diesel oil spray were mechanistically investigated using a phase Doppler anemometry. A two-fluid atomizer was applied for dispersing viscous blends of blended biodiesel oil with designated flow rates. It was experimentally found that the atomizer could generate a spray with large droplets with Sauter mean diameters of ca. 30 μm at low air injection pressure. Such large droplets traveled with a low velocity along their trajectory after emerging from the nozzle tip. The viscosity of blended biodiesel could significantly affect the atomizing process, resulting in the controlled droplet size distribution. Blended biodiesel with a certain fraction of palm oil-based FAME would be consistently atomized owing to its low viscosity. However, the viscosity could exert only a small effect on the droplet velocity profile with the air injection pressure higher than 0.2 MPa.

  17. Method of phase-Doppler anemometry free from the measurement-volume effect.

    Science.gov (United States)

    Qiu, H; Hsu, C T

    1999-05-01

    A novel method is developed to improve the accuracy of particle sizing in laser phase-Doppler anemometry (PDA). In this method the vector sum of refractive and reflective rays is taken into consideration in describing a dual-mechanism-scattering model caused by a nonuniformly illuminated PDA measurement volume. The constraint of the single-mechanism-scattering model in the conventional PDA is removed. As a result the error caused by the measurement-volume effect, which consists of a Gaussian-beam defect and a slit effect, can be eliminated. This new method can be easily implemented with minimal modification of the conventional PDA system. The results of simulation based on the generalized Lorenz-Mie theory show that the new method can provide a PDA system free from the measurement-volume effect.

  18. MEASUREMENTS IN A LIQUID ATOMISER SPRAY USING THE PHASE-DOPPLER PARTICLE ANALYSER

    Directory of Open Access Journals (Sweden)

    R HADEF

    2000-12-01

    Full Text Available Experiments have been carried out at atmospheric conditions using a water atomiser spray. A phase Doppler anemometry was used to perform the measurements of the droplets size, their velocity and concentration, and photographs were taken.  The results showed that the small particles with low turbulence occupied the central core of the jet displaying a Gaussian profile for the axial velocity component.  The large particles were defected towards the outer edges of the jet, due to their higher initial momentum, and displayed relatively high levels of turbulence. The variables measured show that their spatial distributions were nearly symmetrical about the x-axis and although the number density of the droplets is very high in the centred region, most of the pulverised liquid was present in the edges of the spray.

  19. Mechanistic study on spraying of blended biodiesel using phase Doppler anemometry

    Energy Technology Data Exchange (ETDEWEB)

    Kamrak, Juthamas; Kongsombut, Benjapol; Charinpanitkul, Tawatchai [Center of Excellence in Particle Technology, Department of Chemical Engineering, Faculty of Engineering, Chulalongkorn University, Payathai Road, Patumwan, Bangkok 10330 (Thailand); Grehan, Gerard; Saengkaew, Sawitree [LESP/UMR CNRS6614/INSA et Universite de Rouen, BP 12, avenue de l' universite, 76801, Saint Etienne du Rouvray (France); Kim, Kyo-Seon [Department of Chemical Engineering, Faculty of Engineering, Kangwon National University, Chuncheon (Korea)

    2009-10-15

    Droplet size and dynamics of blended palm oil-based fatty acid methyl ester (FAME) and diesel oil spray were mechanistically investigated using a phase Doppler anemometry. A two-fluid atomizer was applied for dispersing viscous blends of blended biodiesel oil with designated flow rates. It was experimentally found that the atomizer could generate a spray with large droplets with Sauter mean diameters of ca. 30 {mu}m at low air injection pressure. Such large droplets traveled with a low velocity along their trajectory after emerging from the nozzle tip. The viscosity of blended biodiesel could significantly affect the atomizing process, resulting in the controlled droplet size distribution. Blended biodiesel with a certain fraction of palm oil-based FAME would be consistently atomized owing to its low viscosity. However, the viscosity could exert only a small effect on the droplet velocity profile with the air injection pressure higher than 0.2 MPa. (author)

  20. Comparison of twin-fluid atomizers using a phase Doppler analyser

    Energy Technology Data Exchange (ETDEWEB)

    Zaremba, Matouš, E-mail: y116215@stud.fme.vutbr.cz, E-mail: y145527@stud.fme.vutbr.cz, E-mail: jedelsky@fme.vutbr.cz, E-mail: jicha@fme.vutbr.cz; Malý, Milan, E-mail: y116215@stud.fme.vutbr.cz, E-mail: y145527@stud.fme.vutbr.cz, E-mail: jedelsky@fme.vutbr.cz, E-mail: jicha@fme.vutbr.cz; Jedelský, Jan, E-mail: y116215@stud.fme.vutbr.cz, E-mail: y145527@stud.fme.vutbr.cz, E-mail: jedelsky@fme.vutbr.cz, E-mail: jicha@fme.vutbr.cz; Jícha, Miroslav, E-mail: y116215@stud.fme.vutbr.cz, E-mail: y145527@stud.fme.vutbr.cz, E-mail: jedelsky@fme.vutbr.cz, E-mail: jicha@fme.vutbr.cz [Brno University of technology, Technická 2896/2, 616 69 Brno (Czech Republic)

    2014-08-06

    The quality of atomization is crucial in combustion processes, especially in cases of highly viscous fuels. Twin-fluid atomizers have been developed for atomizing heavy and waste fuels and they have undergone significant development in the last decades. Nevertheless, in order to design an atomizer for a given industrial application, a comparison of different atomizers at similar operating conditions is required. This paper focuses on the description and comparison of two internally mixed twin-fluid atomizers at the same operating regime. The Y-jet and the Inverse-effervescent atomizers were examined. The phase-Doppler analyzer was used to measure the velocity and size of droplets in a radial profile in the spray. Data were sorted out into classes with respect to the droplet size and the motion analysis was done for both atomizers.

  1. Doppler Tomography

    Science.gov (United States)

    Marsh, T. R.

    I review the method of Doppler tomography which translates binary-star line profiles taken at a series of orbital phases into a distribution of emission over the binary. I begin with a discussion of the basic principles behind Doppler tomography, including a comparison of the relative merits of maximum entropy regularisation versus filtered back-projection for implementing the inversion. Following this I discuss the issue of noise in Doppler images and possible methods for coping with it. Then I move on to look at the results of Doppler Tomography applied to cataclysmic variable stars. Outstanding successes to date are the discovery of two-arm spiral shocks in cataclysmic variable accretion discs and the probing of the stream/magnetospheric interaction in magnetic cataclysmic variable stars. Doppler tomography has also told us much about the stream/disc interaction in non-magnetic systems and the irradiation of the secondary star in all systems. The latter indirectly reveals such effects as shadowing by the accretion disc or stream. I discuss all of these and finish with some musings on possible future directions for the method. At the end I include a tabulation of Doppler maps published in refereed journals.

  2. Itinerant Ferromagnetism in a Polarized Two-Component Fermi Gas

    DEFF Research Database (Denmark)

    Massignan, Pietro; Yu, Zhenhua; Bruun, Georg

    2013-01-01

    We analyze when a repulsively interacting two-component Fermi gas becomes thermodynamically unstable against phase separation. We focus on the strongly polarized limit, where the free energy of the homogeneous mixture can be calculated accurately in terms of well-defined quasiparticles, the repul......We analyze when a repulsively interacting two-component Fermi gas becomes thermodynamically unstable against phase separation. We focus on the strongly polarized limit, where the free energy of the homogeneous mixture can be calculated accurately in terms of well-defined quasiparticles...

  3. A Pedestrian Detection Scheme Using a Coherent Phase Difference Method Based on 2D Range-Doppler FMCW Radar

    Science.gov (United States)

    Hyun, Eugin; Jin, Young-Seok; Lee, Jong-Hun

    2016-01-01

    For an automotive pedestrian detection radar system, fast-ramp based 2D range-Doppler Frequency Modulated Continuous Wave (FMCW) radar is effective for distinguishing between moving targets and unwanted clutter. However, when a weak moving target such as a pedestrian exists together with strong clutter, the pedestrian may be masked by the side-lobe of the clutter even though they are notably separated in the Doppler dimension. To prevent this problem, one popular solution is the use of a windowing scheme with a weighting function. However, this method leads to a spread spectrum, so the pedestrian with weak signal power and slow Doppler may also be masked by the main-lobe of clutter. With a fast-ramp based FMCW radar, if the target is moving, the complex spectrum of the range- Fast Fourier Transform (FFT) is changed with a constant phase difference over ramps. In contrast, the clutter exhibits constant phase irrespective of the ramps. Based on this fact, in this paper we propose a pedestrian detection for highly cluttered environments using a coherent phase difference method. By detecting the coherent phase difference from the complex spectrum of the range-FFT, we first extract the range profile of the moving pedestrians. Then, through the Doppler FFT, we obtain the 2D range-Doppler map for only the pedestrian. To test the proposed detection scheme, we have developed a real-time data logging system with a 24 GHz FMCW transceiver. In laboratory tests, we verified that the signal processing results from the proposed method were much better than those expected from the conventional 2D FFT-based detection method. PMID:26805835

  4. A Pedestrian Detection Scheme Using a Coherent Phase Difference Method Based on 2D Range-Doppler FMCW Radar

    Directory of Open Access Journals (Sweden)

    Eugin Hyun

    2016-01-01

    Full Text Available For an automotive pedestrian detection radar system, fast-ramp based 2D range-Doppler Frequency Modulated Continuous Wave (FMCW radar is effective for distinguishing between moving targets and unwanted clutter. However, when a weak moving target such as a pedestrian exists together with strong clutter, the pedestrian may be masked by the side-lobe of the clutter even though they are notably separated in the Doppler dimension. To prevent this problem, one popular solution is the use of a windowing scheme with a weighting function. However, this method leads to a spread spectrum, so the pedestrian with weak signal power and slow Doppler may also be masked by the main-lobe of clutter. With a fast-ramp based FMCW radar, if the target is moving, the complex spectrum of the range- Fast Fourier Transform (FFT is changed with a constant phase difference over ramps. In contrast, the clutter exhibits constant phase irrespective of the ramps. Based on this fact, in this paper we propose a pedestrian detection for highly cluttered environments using a coherent phase difference method. By detecting the coherent phase difference from the complex spectrum of the range-FFT, we first extract the range profile of the moving pedestrians. Then, through the Doppler FFT, we obtain the 2D range-Doppler map for only the pedestrian. To test the proposed detection scheme, we have developed a real-time data logging system with a 24 GHz FMCW transceiver. In laboratory tests, we verified that the signal processing results from the proposed method were much better than those expected from the conventional 2D FFT-based detection method.

  5. Prise en compte de la dimension finie des faisceaux d'éclairage en granulométrie optique: anémométrie phase Doppler

    OpenAIRE

    Onofri, Fabrice

    1995-01-01

    The optical diagnosis by phase Doppler anemometry of particles encountered in two­phase flows require the use of focused laser beams. The influence of the intensity gradients induced on the particle surface is considered in the first part of this manuscript. Several new phase Doppler geometries are proposed, enabling to suppress the errors induced by the so­called « trajectory effects ». The second part of this work deals with the extension of the phase Doppler anemometry to particle refracti...

  6. Evaluation of droplet velocity and size from nasal spray devices using phase Doppler anemometry (PDA).

    Science.gov (United States)

    Liu, Xiaofei; Doub, William H; Guo, Changning

    2010-03-30

    To determine aerosol deposition during the inhalation drug delivery, it is important to understand the combination of velocity and droplet size together. In this study, phase Doppler anemometry (PDA) was used to simultaneously characterize the aerosol velocity and droplet size distribution (DSD) of three nasal spray pumps filled with water. Thirteen sampling positions were located in the horizontal cross-sectional area of the nasal spray plumes at a distance of 3cm from the pump orifice. The results showed droplet velocities near the center of the spray plume were higher and more consistent than those near the edge. The pumps examined showed significant differences in their aerosol velocity at the center of the spray plume, which suggest that this metric might be used as a discriminating parameter for in vitro testing of nasal sprays. Droplet size measurements performed using PDA were compared with results from laser light scattering measurements. The ability of PDA to provide simultaneous measurements of aerosol velocity and size makes it a powerful tool for the detailed investigation of nasal spray plume characteristics. Published by Elsevier B.V.

  7. Experimental study on spray characteristics of alternate jet fuels using Phase Doppler Anemometry

    Science.gov (United States)

    Kannaiyan, Kumaran; Sadr, Reza

    2013-11-01

    Gas-to-Liquid (GTL) fuels have gained global attention due to their cleaner combustion characteristics. The chemical and physical properties of GTL jet fuels are different from conventional jet fuels owing to the difference in their production methodology. It is important to study the spray characteristics of GTL jet fuels as the change of physical properties can affect atomization, mixing, evaporation and combustion process, ultimately affecting emission process. In this work, spray characteristics of two GTL synthetic jet fuels are studied using a pressure-swirl nozzle at different injection pressures and atmospheric ambient condition. Phase Doppler Anemometry (PDA) measurements of droplet size and velocity are compared with those of regular Jet A-1 fuel at several axial and radial locations downstream of the nozzle exit. Experimental results show that although the GTL fuels have different physical properties such as viscosity, density, and surface tension, among each other the resultant change in the spray characteristics is insignificant. Furthermore, the presented results show that GTL fuel spray characteristics exhibit close similarity to those of Jet A-1 fuel. Funded by Qatar Science and Technology Park.

  8. Evaluation of metered dose inhaler spray velocities using phase Doppler anemometry (PDA).

    Science.gov (United States)

    Liu, Xiaofei; Doub, William H; Guo, Changning

    2012-02-28

    Droplet velocity is an important parameter which can significantly influence inhalation drug delivery performance. Together with the droplet size, this parameter determines the efficiency of the deposition of MDI products at different sites within the lungs. In this study, phase Doppler anemometry (PDA) was used to investigate the instantaneous droplet velocity emitted from MDIs as well as the corresponding droplet size distribution. The nine commercial MDI products surveyed showed significantly different droplet velocities, indicating that droplet velocity could be used as a discriminating parameter for in vitro testing of MDI products. The droplet velocity for all tested MDI products decreased when the testing distance was increased from 3 cm to 6 cm from the front of mouthpiece, with CFC formulations showing a larger decrease than HFA formulations. The mean droplet diameters of the nine MDIs were also significantly different from one-another. Droplet size measurements made using PDA (a number-based technique) could not be directly compared to results obtained using laser light scattering measurements (a volume-based technique). This work demonstrates that PDA can provide unique information useful for characterizing MDI aerosol plumes and evaluating MDI drug delivery efficiency. PDA could also aid the evaluation of in vitro equivalence in support of formulation or manufacturing changes and in evaluation of abbreviated new drug applications (ANDAs) for MDIs. Published by Elsevier B.V.

  9. Assessment of the influence factors on nasal spray droplet velocity using phase-Doppler anemometry (PDA).

    Science.gov (United States)

    Liu, Xiaofei; Doub, William H; Guo, Changning

    2011-03-01

    Droplet velocity is an important parameter that can be used to characterize nasal spray products. In this study, a phase-Doppler anemometry (PDA) system was used to measure the droplet velocities of nasal sprays. A survey of seven commercial nasal spray products showed a range of droplet velocities from 6.7 to 19.2 m/s, all significantly different from each other. A three-level, four-factor Box-Behnken design of experiments (DOE) methodology were applied to investigate the influences of actuation parameters and formulation properties on nasal spray droplet velocity using a set of placebo formulations. The DOE study shows that all four input factors (stroke length, actuation velocity, concentration of the gelling agent, and concentration of the surfactant) have significant influence on droplet velocity. An optimized quadratic model generated from the DOE results describes the inherent relationships between the input factors and droplet velocity thus providing a better understanding of the input factor influences. Overall, PDA provides a new in vitro characterization method for the evaluation of inhalation drugs through assessment of spray velocity and may assist in product development to meet drug delivery equivalency requirements. © 2011 American Association of Pharmaceutical Scientists

  10. Comparison of Global Sizing Velocimetry and Phase Doppler Anemometry measurements of alternative jet fuel sprays

    Science.gov (United States)

    Sadr, Reza; Kannaiyan, Kumaran

    2013-11-01

    Atomization plays a crucial precursor role in liquid fuel combustion that directly affects the evaporation, mixing, and emission levels. Laser diagnostic techniques are often used to study the spray characteristics of liquid fuels. The objective of this work is to compare the spray measurements of Gas-to Liquid (GTL) jet fuels obtained using Global Sizing Velocimetry (GSV) and Phase Doppler Anemometry (PDA) techniques at global and local levels, respectively. The chemical and physical properties of GTL fuels are different from conventional jet fuels, owing to the difference in their production methodology. In this work, the experimental facility, the measurement techniques, and spray characteristics of two different GTL fuels are discussed and compared with those of Jet A-1 fuel. Results clearly demonstrate that although the global measurement gives an overall picture of the spray, fine details are obtained only through local measurements and complement in gaining more inferences into the spray characteristics. The results also show a close similarity in spray characteristics between GTL and Jet A-1 fuels. Funded by Qatar Science and Technology Park.

  11. Two component plasma vortex approach to fusion

    International Nuclear Information System (INIS)

    Ikuta, Kazunari.

    1978-09-01

    Two component operation of the field reversed theta pinch plasma by injection of the energetic ion beam with energy of the order of 1 MeV is considered. A possible trapping scheme of the ion beam in the plasma is discussed in detail. (author)

  12. Quantitative measurement of total cerebral blood flow using 2D phase-contrast MRI and doppler ultrasound

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Keum Soo; Choi, Sun Seob; Lee, Young Il [Dong-A Univ., College of Medicine, Busan (Korea, Republic of)

    2001-12-01

    To compare of quantitative measurement of the total cerebral blood flow using two-dimensional phase-contrast MR imaging and Doppler ultrasound. In 16 volunteers (mean age, 26 years; mean body weight, 66 kg) without abnormal medical histories, two-dimensional phase-contrast MR imaging was performed at the level of the C2-3 inter vertebral disc for flow measurement of the internal carotid arteries and the vertebral arteries. Volume flow measurements using Doppler ultrasound were also performed at the internal carotid arteries 2cm above the carotid bifurcation, and at the vertebral arteries at the level of the upper pole of the thyroid gland. Flows in the four vessels measured by the two methods were compared using Wilcoxon's correlation analysis and the median score. Total cerebral blood flows were calculated by summing these four vessel flows, and mean values for the 16 volunteers were calculated. Cerebral blood flows measured by 2-D phase-contrast MR imaging and Doppler ultrasounds were 233 and 239 ml/min in the right internal carotid artery, 250 and 248 ml/min in the left internal carotid artery, 62 and 56 ml/min in the right vertebral artery, and 83 and 68 ml/min in the left vertebral artery. Correlation coefficients of the blood flows determined by the two methods were 0.48, 0.54, 0.49, and 0.62 in each vessel, while total cerebral blood flows were 628{+-}68 (range, 517 to 779) ml/min and 612{+-}79 (range, 482 to 804)ml/min, respectively. Total cerebral blood flow was easily measured using 2-D phase-contrast MR imaging and Doppler ultrasound, and the two noninvasive methods can therefore be used clinically for the measurement of total cerebral blood flow.

  13. Value of the Doppler index of myocardial performance in the early phase of acute myocardial infarction

    DEFF Research Database (Denmark)

    Poulsen, S H; Jensen, S E; Tei, C

    2000-01-01

    Prospective assessment of a nongeometric Doppler-derived index of combined systolic and diastolic myocardial performance was performed in 64 patients with acute myocardial infarction (MI) within 1 hour after their arrival to the hospital and in 39 age-matched healthy subjects. The index is defined...

  14. A case study of microphysical structures and hydrometeor phase in convection using radar Doppler spectra at Darwin, Australia

    International Nuclear Information System (INIS)

    Riihimaki, Laura D.; Comstock, J. M.; Luke, E.; Thorsen, T. J.; Fu, Q.

    2017-01-01

    To understand the microphysical processes that impact diabatic heating and cloud lifetimes in convection, we need to characterize the spatial distribution of supercooled liquid water. To address this observational challenge, ground-based vertically pointing active sensors at the Darwin Atmospheric Radiation Measurement site are used to classify cloud phase within a deep convective cloud. The cloud cannot be fully observed by a lidar due to signal attenuation. Therefore, we developed an objective method for identifying hydrometeor classes, including mixed-phase conditions, using k-means clustering on parameters that describe the shape of the Doppler spectra from vertically pointing Ka-band cloud radar. Furthermore, this approach shows that multiple, overlapping mixed-phase layers exist within the cloud, rather than a single region of supercooled liquid. Diffusional growth calculations show that the conditions for the Wegener-Bergeron-Findeisen process exist within one of these mixed-phase microstructures.

  15. A case study of microphysical structures and hydrometeor phase in convection using radar Doppler spectra at Darwin, Australia

    Science.gov (United States)

    Riihimaki, L. D.; Comstock, J. M.; Luke, E.; Thorsen, T. J.; Fu, Q.

    2017-07-01

    To understand the microphysical processes that impact diabatic heating and cloud lifetimes in convection, we need to characterize the spatial distribution of supercooled liquid water. To address this observational challenge, ground-based vertically pointing active sensors at the Darwin Atmospheric Radiation Measurement site are used to classify cloud phase within a deep convective cloud. The cloud cannot be fully observed by a lidar due to signal attenuation. Therefore, we developed an objective method for identifying hydrometeor classes, including mixed-phase conditions, using k-means clustering on parameters that describe the shape of the Doppler spectra from vertically pointing Ka-band cloud radar. This approach shows that multiple, overlapping mixed-phase layers exist within the cloud, rather than a single region of supercooled liquid. Diffusional growth calculations show that the conditions for the Wegener-Bergeron-Findeisen process exist within one of these mixed-phase microstructures.

  16. Two Component Signal Transduction in Desulfovibrio Species

    Energy Technology Data Exchange (ETDEWEB)

    Luning, Eric; Rajeev, Lara; Ray, Jayashree; Mukhopadhyay, Aindrila

    2010-05-17

    The environmentally relevant Desulfovibrio species are sulfate-reducing bacteria that are of interest in the bioremediation of heavy metal contaminated water. Among these, the genome of D. vulgaris Hildenborough encodes a large number of two component systems consisting of 72 putative response regulators (RR) and 64 putative histidinekinases (HK), the majority of which are uncharacterized. We classified the D. vulgaris Hildenborough RRs based on their output domains and compared the distribution of RRs in other sequenced Desulfovibrio species. We have successfully purified most RRs and several HKs as His-tagged proteins. We performed phospho-transfer experiments to verify relationships between cognate pairs of HK and RR, and we have also mapped a few non-cognate HK-RR pairs. Presented here are our discoveries from the Desulfovibrio RR categorization and results from the in vitro studies using purified His tagged D. vulgaris HKs and RRs.

  17. Conductivity of two-component systems

    Energy Technology Data Exchange (ETDEWEB)

    Kuijper, A. de; Hofman, J.P.; Waal, J.A. de [Shell Research BV, Rijswijk (Netherlands). Koninklijke/Shell Exploratie en Productie Lab.; Sandor, R.K.J. [Shell International Petroleum Maatschappij, The Hague (Netherlands)

    1996-01-01

    The authors present measurements and computer simulation results on the electrical conductivity of nonconducting grains embedded in a conductive brine host. The shapes of the grains ranged from prolate-ellipsoidal (with an axis ratio of 5:1) through spherical to oblate-ellipsoidal (with an axis ratio of 1:5). The conductivity was studied as a function of porosity and packing, and Archie`s cementation exponent was found to depend on porosity. They used spatially regular and random configurations with aligned and nonaligned packings. The experimental results agree well with the computer simulation data. This data set will enable extensive tests of models for calculating the anisotropic conductivity of two-component systems.

  18. Global rainbow thermometry assessed by Airy and Lorenz-Mie theories and compared with phase Doppler anemometry.

    Science.gov (United States)

    van Beeck, Jeronimus Petrus Antonius Johannes; Grosges, Thomas; De Giorgi, Maria Grazia

    2003-07-01

    Global rainbow thermometry (GRT) measures the mean size and temperature of an ensemble of spray droplets. The domain of validity of the Airy theory for this technique is established through comparison with Lorenz-Mie theory. The temperature derivation from the inflection points of the Airy rainbow pattern appears to be independent of the type of spray dispersion. Measurements in a water spray are reported. The mean diameter obtained from the rainbow pattern lies between the arithmetic and the Sauter mean diameters measured by phase Doppler anemometry. The temperature measurement by GRT is shown to be accurate within a few degrees Celsius.

  19. A case study of microphysical structures and hydrometeor phase in convection using radar Doppler spectra at Darwin, Australia

    Energy Technology Data Exchange (ETDEWEB)

    Riihimaki, Laura D.; Comstock, Jennifer M.; Luke, Edward; Thorsen, Tyler J.; Fu, Qiang

    2017-07-28

    To understand the microphysical processes that impact diabatic heating and cloud lifetimes in convection, we need to characterize the spatial distribution of supercooled liquid water. To address this observational challenge, vertically pointing active sensors at the Darwin Atmospheric Radiation Measurement (ARM) site are used to classify cloud phase within a deep convective cloud in a shallow to deep convection transitional case. The cloud cannot be fully observed by a lidar due to signal attenuation. Thus we develop an objective method for identifying hydrometeor classes, including mixed-phase conditions, using k-means clustering on parameters that describe the shape of the Doppler spectra from vertically pointing Ka band cloud radar. This approach shows that multiple, overlapping mixed-phase layers exist within the cloud, rather than a single region of supercooled liquid, indicating complexity to how ice growth and diabatic heating occurs in the vertical structure of the cloud.

  20. Vortex formation in a rotating two-component Fermi gas

    Energy Technology Data Exchange (ETDEWEB)

    Warringa, Harmen J.; Sedrakian, Armen [Institut fuer Theoretische Physik, Goethe-Universitaet Frankfurt am Main, Max-von-Laue-Strasse 1, D-60438 Frankfurt am Main (Germany)

    2011-08-15

    A two-component Fermi gas with attractive s-wave interactions forms a superfluid at low temperatures. When this gas is confined in a rotating trap, fermions can unpair at the edges of the gas and vortices can arise beyond certain critical rotation frequencies. We compute these critical rotation frequencies and construct the phase diagram in the plane of scattering length and rotation frequency for different total numbers of particles. We work at zero temperature and consider a cylindrically symmetric harmonic trapping potential. The calculations are performed in the Hartree-Fock-Bogoliubov approximation which implies that our results are quantitatively reliable for weak interactions.

  1. Innovative Coal Solids-Flow Monitoring and Measurement Using Phase-Doppler and Mie Scattering Techniques

    Energy Technology Data Exchange (ETDEWEB)

    Stephen Seong Lee

    2010-01-19

    Fuel flow to individual burners is complicated and difficult to determine on coal fired boilers, since coal solids were transported in a gas suspension that is governed by the complex physics of two-phase flow. The objectives of the project were the measurements of suspended coal solids-flows in the simulated test conditions. Various extractive methods were performed manually and can give only a snapshot result of fuel distribution. In order to measure particle diameter & velocity, laser based phase-Doppler particle analyzer (PDPA) and particle image velocimetry (PIV) were carefully applied. Statistical methods were used to analyze particle characteristics to see which factors have significant effect. The transparent duct model was carefully designed and fabricated for the laser-based-instrumentation of solids-flow monitoring (LISM). The experiments were conducted with two different kinds of particles with four different particle diameters. The particle types were organic particles and saw dust particles with the diameter range of 75-150 micron, 150-250 micron, 250-355 micron and 355-425 micron. The densities of the particles were measured to see how the densities affected the test results. Also the experiment was conducted with humid particles and fog particles. To generate humid particles, the humidifier was used. A pipe was connected to the humidifier to lead the particle flow to the intersection of the laser beam. The test results of the particle diameter indicated that, the mean diameter of humid particles was between 6.1703 microns and 6.6947 microns when the humid particle flow was low. When the humid particle flow was high, the mean diameter was between 6.6728 microns and 7.1872 microns. The test results of the particle mean velocity indicated that the mean velocity was between 1.3394 m/sec and 1.4556 m/sec at low humid particle flow. When the humid particle flow was high, the mean velocity was between 1.5694 m/sec and 1.7856 m/sec. The Air Flow Module, TQ

  2. The Next Generation of Airborne Polarimetric Doppler Weather Radar: NCAR/EOL Airborne Phased Array Radar (APAR) Development

    Science.gov (United States)

    Moore, James; Lee, Wen-Chau; Loew, Eric; Vivekanandan, Jothiram; Grubišić, Vanda; Tsai, Peisang; Dixon, Mike; Emmett, Jonathan; Lord, Mark; Lussier, Louis; Hwang, Kyuil; Ranson, James

    2017-04-01

    The National Center for Atmospheric Research (NCAR) Earth observing Laboratory (EOL) is entering the third year of preliminary system design studies, engineering prototype testing and project management plan preparation for the development of a novel Airborne Phased Array Radar (APAR). This system being designed by NCAR/EOL will be installed and operated on the NSF/NCAR C-130 aircraft. The APAR system will consist of four removable C-band Active Electronically Scanned Arrays (AESA) strategically placed on the fuselage of the aircraft. Each AESA measures approximately 1.5 x 1.9 m and is composed of 3000 active radiating elements arranged in an array of line replaceable units (LRU) to simplify maintenance. APAR will provide unprecedented observations, and in conjunction with the advanced radar data assimilation schema, will be able to address the key science questions to improve understanding and predictability of significant and high-impact weather APAR, operating at C-band, allows the measurement of 3-D kinematics of the more intense portions of storms (e.g. thunderstorm dynamics and tornadic development, tropical cyclone rainband structure and evolution) with less attenuation compared with current airborne Doppler radar systems. Polarimetric measurements are not available from current airborne tail Doppler radars. However, APAR, with dual-Doppler and dual polarization diversity at a lesser attenuating C-band wavelength, will further advance the understanding of the microphysical processes within a variety of precipitation systems. The radar is sensitive enough to provide high resolution measurements of winter storm dynamics and microphysics. The planned APAR development that would bring the system to operational readiness for research community use aboard the C-130 is expected to take 8 years once major funding support is realized. The authors will review the overall APAR design and provide new details of the system based on our Technical Requirements Document

  3. Left ventricular diastolic dyssynchrony assessed with phase analysis of gated myocardial perfusion SPECT: a comparison with tissue Doppler imaging

    International Nuclear Information System (INIS)

    Boogers, Mark J.; Veltman, Caroline E.; Chen, Ji; Garcia, Ernest V.; Bommel, Rutger J. van; Mooyaart, Eline A.Q.; Wall, Ernst E. van der; Schalij, Martin J.; Bax, Jeroen J.; Delgado, Victoria; Younis, Imad Al; Hiel, Bernies van der; Dibbets-Schneider, Petra

    2011-01-01

    The aim of the current study was to evaluate the feasibility of phase analysis on gated myocardial perfusion SPECT (GMPS) for the assessment of left ventricular (LV) diastolic dyssynchrony in a head-to-head comparison with tissue Doppler imaging (TDI). The population consisted of patients with end-stage heart failure of New York Heart Association functional class III or IV with a reduced LV ejection fraction of ≤35%. LV diastolic dyssynchrony was calculated using TDI as the maximal time delay between early peak diastolic velocities of two opposing left ventricle walls (diastolic mechanical delay). Significant LV diastolic dyssynchrony was defined as a diastolic mechanical delay of >55 ms on TDI. Furthermore, phase analysis on GMPS was performed to evaluate LV diastolic dyssynchrony; diastolic phase standard deviation (SD) and histogram bandwidth (HBW) were used as markers of LV diastolic dyssynchrony. A total of 150 patients (114 men, mean age 66.0 ± 10.4 years) with end-stage heart failure were enrolled. Both diastolic phase SD (r = 0.81, p 55 ms) showed significantly larger diastolic phase SD (68.1 ± 13.4 vs. 40.7 ± 14.0 , p < 0.01) and diastolic HBW (230.6 ± 54.3 vs. 129.0 ± 55.6 , p < 0.01) as compared to patients without LV diastolic dyssynchrony on TDI (≤55 ms). Finally, phase analysis on GMPS showed a good intra- and interobserver reproducibility for the determination of diastolic phase SD (ICC 0.97 and 0.88) and diastolic HBW (ICC 0.98 and 0.93). Phase analysis on GMPS showed good correlations with TDI for the assessment of LV diastolic dyssynchrony. (orig.)

  4. Experimental Study on The Two-Phase Flow Characteristics Using Conductivity Probes And Laser Doppler Anemometry In A Vertical Pipe

    Science.gov (United States)

    Chiva, S.; Mendez, S.; Muñoz-Cobo, J. L.; Julia, J. E.; Hernandez, L.

    2007-06-01

    An upward isothermal co-current air-water flow in a vertical pipe (50.2 mm inner diameter) has been experimental investigated. Local measurements of void fraction, interfacial area concentration (IAC), interfacial velocity and Sauter mean diameter were measured using a double sensor conductivity probe. Liquid velocity and turbulence intensity were measured using Laser Doppler Anemometry (LDA). Different air-water flow configurations was investigated for a liquid flow rate ranged from 0.491 m/s to 0.981 m/s and a void fraction up to 10 %. For each two-phase flow configuration twenty five radial position and three axial locations were measured by the conductivity probe methodology, and several radial profiles was measured with LDA at different axial positions.

  5. Study of cyclic and steady particle motion in a realistic human airway model using phase-Doppler anemometry

    Science.gov (United States)

    Jedelský, Jan; Lízal, František; Jícha, Miroslav

    2012-04-01

    Transport and deposition of particles in human airways has been of research interest for many years. Various experimental methods such as constant temperature anemometry, particle image velocimetry and laser-Doppler based techniques were employed for study of aerosol transport in the past. We use Phase-Doppler Particle Analyser (P/DPA) for time resolved size and velocity measurement of liquid aerosol particles in a size range 1 to 8 μm. The di-2ethylhexyl sabacate (DEHS) particles were produced by condensation monodisperse aerosol generator. A thin-wall transparent model of human airways with non-symmetric bifurcations and non-planar geometry containing parts from throat to 3rd-4th generation of bronchi was fabricated for the study. Several cyclic (sinusoidal) breathing regimes were simulated using pneumatic breathing mechanism. Analogous steady-flow regimes were also investigated and used for comparison. An analysis of the particle velocity data was performed with aim to gain deeper understanding of the transport phenomena in the realistic bifurcating airway system. Flows of particles of different sizes in range 1 - 10 μm was found to slightly differ for extremely high Stokes numbers. Differences in steady and cyclic turbulence intensities were documented in the paper. Systematically higher turbulence intensity was found for cyclic flows and mainly in the expiration breathing phase. Negligible differences were found for behaviour of different particle size classes in the inspected range 1 to 8 μm. Possibility of velocity spectra estimation of air flow using the P/DPA data is discussed.

  6. Study of cyclic and steady particle motion in a realistic human airway model using phase-Doppler anemometry

    Directory of Open Access Journals (Sweden)

    Jícha Miroslav

    2012-04-01

    Full Text Available Transport and deposition of particles in human airways has been of research interest for many years. Various experimental methods such as constant temperature anemometry, particle image velocimetry and laser-Doppler based techniques were employed for study of aerosol transport in the past. We use Phase-Doppler Particle Analyser (P/DPA for time resolved size and velocity measurement of liquid aerosol particles in a size range 1 to 8 μm. The di-2ethylhexyl sabacate (DEHS particles were produced by condensation monodisperse aerosol generator. A thin-wall transparent model of human airways with non-symmetric bifurcations and non-planar geometry containing parts from throat to 3rd-4th generation of bronchi was fabricated for the study. Several cyclic (sinusoidal breathing regimes were simulated using pneumatic breathing mechanism. Analogous steady-flow regimes were also investigated and used for comparison. An analysis of the particle velocity data was performed with aim to gain deeper understanding of the transport phenomena in the realistic bifurcating airway system. Flows of particles of different sizes in range 1 – 10 μm was found to slightly differ for extremely high Stokes numbers. Differences in steady and cyclic turbulence intensities were documented in the paper. Systematically higher turbulence intensity was found for cyclic flows and mainly in the expiration breathing phase. Negligible differences were found for behaviour of different particle size classes in the inspected range 1 to 8 μm. Possibility of velocity spectra estimation of air flow using the P/DPA data is discussed.

  7. Study of the movement of oxygen vacancies in the orthorhombic phase of YBa2Cu3O7-x by positron Doppler broadening spectroscopy

    International Nuclear Information System (INIS)

    Hong Zhang; Xiao-Gan Wang; Yao-Xian Fu

    1988-01-01

    The positron annihilation Doppler spectroscopy is used to monitor the movement of oxygen vacancy of YBa 2 Cu 3 O 7-x and an activation energy of (0.80 ± 0.10) eV for migration of oxygen vacancy in orthorhombic phase is obtained. (author)

  8. Chemical evolution of two-component galaxies. II

    International Nuclear Information System (INIS)

    Caimmi, R.

    1978-01-01

    In order to confirm and refine the results obtained in a previous paper the chemical evolution of two-component (spheroid + disk) galaxies is derived rejecting the instantaneous recycling approximation, by means of numerical computations, accounting for (i) the collapse phase of the gas, assumed to be uniform in density and composition, and (ii) a birth-rate stellar function. Computations are performed relatively to the solar neighbourhood and to model galaxies which closely resemble the real morphological sequence: in both cases, numerical results are compared with analytical ones. The numerical models of this paper constitute a first-order approximation, while higher order approximations could be made by rejecting the hypothesis of uniform density and composition, and making use of detailed dynamical models. (Auth.)

  9. Quantitative measurement of portal blood flow by magnetic resonance phase contrast. Comparative study of flow phantom and Doppler ultrasound in vivo

    International Nuclear Information System (INIS)

    Tsunoda, Masatoshi; Kimoto, Shin; Hamazaki, Keisuke; Takeda, Yoshihiro; Hiraki, Yoshio.

    1994-01-01

    A non-invasive method for measuring portal blood flow by magnetic resonance (MR) phase contrast was evaluated in a flow phantom and 20 healthy volunteers. In a flow phantom study, the flow volumes and mean flow velocities measured by MR phase contrast showed close correlations with those measured by electromagnetic flow-metry. In 20 healthy volunteers, the cross-sectional areas, flow volumes and mean flow velocities measured by MR phase contrast correlated well with those measured by the Doppler ultrasound method. Portal blood flow averaged during the imaging time could be measured under natural breathing conditions by using a large number of acquisitions without the limitations imposed on the Doppler ultrasound method. MR phase contrast is considered to be useful for the non-invasive measurement of portal blood flow. (author)

  10. Onsager Vortex Formation in Two-component Bose-Einstein Condensates

    Science.gov (United States)

    Han, Junsik; Tsubota, Makoto

    2018-06-01

    We numerically study the dynamics of quantized vortices in two-dimensional two-component Bose-Einstein condensates (BECs) trapped by a box potential. For one-component BECs in a box potential, it is known that quantized vortices form Onsager vortices, which are clusters of same-sign vortices. We confirm that the vortices of the two components spatially separate from each other — even for miscible two-component BECs — suppressing the formation of Onsager vortices. This phenomenon is caused by the repulsive interaction between vortices belonging to different components, hence, suggesting a new possibility for vortex phase separation.

  11. Heterodyne laser Doppler distance sensor with phase coding measuring stationary as well as laterally and axially moving objects

    International Nuclear Information System (INIS)

    Pfister, T; Günther, P; Nöthen, M; Czarske, J

    2010-01-01

    Both in production engineering and process control, multidirectional displacements, deformations and vibrations of moving or rotating components have to be measured dynamically, contactlessly and with high precision. Optical sensors would be predestined for this task, but their measurement rate is often fundamentally limited. Furthermore, almost all conventional sensors measure only one measurand, i.e. either out-of-plane or in-plane distance or velocity. To solve this problem, we present a novel phase coded heterodyne laser Doppler distance sensor (PH-LDDS), which is able to determine out-of-plane (axial) position and in-plane (lateral) velocity of rough solid-state objects simultaneously and independently with a single sensor. Due to the applied heterodyne technique, stationary or purely axially moving objects can also be measured. In addition, it is shown theoretically as well as experimentally that this sensor offers concurrently high temporal resolution and high position resolution since its position uncertainty is in principle independent of the lateral object velocity in contrast to conventional distance sensors. This is a unique feature of the PH-LDDS enabling precise and dynamic position and shape measurements also of fast moving objects. With an optimized sensor setup, an average position resolution of 240 nm was obtained

  12. Non-invasive classification of gas–liquid two-phase horizontal flow regimes using an ultrasonic Doppler sensor and a neural network

    OpenAIRE

    Abbagoni, Baba Musa; Yeung, Hoi

    2016-01-01

    The identification of flow pattern is a key issue in multiphase flow which is encountered in the petrochemical industry. It is difficult to identify the gas–liquid flow regimes objectively with the gas–liquid two-phase flow. This paper presents the feasibility of a clamp-on instrument for an objective flow regime classification of two-phase flow using an ultrasonic Doppler sensor and an artificial neural network, which records and processes the ultrasonic signals reflected from the two-phase ...

  13. Doppler Aliasing Reduction in Wide-Angle Synthetic Aperture Radar Using Phase Modulated Random Stepped-Frequency Waveforms

    National Research Council Canada - National Science Library

    Hyatt, Andrew W

    2006-01-01

    ...) waveforms in a Wide-Angle Synthetic Aperture Radar (WA-SAR) scenario. RSF waveforms have been demonstrated to have desirable properties which allow for cancelling of Doppler aliased scatterers in WA-SAR images...

  14. Prevention of conversion to abnormal transcranial Doppler with hydroxyurea in sickle cell anemia: A Phase III international randomized clinical trial.

    Science.gov (United States)

    Hankins, Jane S; McCarville, Mary Beth; Rankine-Mullings, Angela; Reid, Marvin E; Lobo, Clarisse L C; Moura, Patricia G; Ali, Susanna; Soares, Deanne P; Aldred, Karen; Jay, Dennis W; Aygun, Banu; Bennett, John; Kang, Guolian; Goldsmith, Jonathan C; Smeltzer, Matthew P; Boyett, James M; Ware, Russell E

    2015-12-01

    Children with sickle cell anemia (SCA) and conditional transcranial Doppler (TCD) ultrasound velocities (170-199 cm/sec) may develop stroke. However, with limited available clinical data, the current standard of care for conditional TCD velocities is observation. The efficacy of hydroxyurea in preventing conversion from conditional to abnormal TCD (≥200 cm/sec), which confers a higher stroke risk, has not been studied prospectively in a randomized trial. Sparing Conversion to Abnormal TCD Elevation (SCATE #NCT01531387) was a National Heart, Lung, and Blood Institute-funded Phase III multicenter international clinical trial comparing alternative therapy (hydroxyurea) to standard care (observation) to prevent conversion from conditional to abnormal TCD velocity in children with SCA. SCATE enrolled 38 children from the United States, Jamaica, and Brazil [HbSS (36), HbSβ(0) -thalassemia (1), and HbSD (1), median age = 5.4 years (range, 2.7-9.8)]. Because of the slow patient accrual and administrative delays, SCATE was terminated early. In an intention-to-treat analysis, the cumulative incidence of abnormal conversion was 9% (95% CI = 0-35%) in the hydroxyurea arm and 47% (95% CI = 6-81%) in observation arm at 15 months (P = 0.16). In post hoc analysis according to treatment received, significantly fewer children on hydroxyurea converted to abnormal TCD velocities when compared with observation (0% vs. 50%, P = 0.02). After a mean of 10.1 months, a significant change in mean TCD velocity was observed with hydroxyurea treatment (-15.5 vs. +10.2 cm/sec, P = 0.02). No stroke events occurred in either arm. Hydroxyurea reduces TCD velocities in children with SCA and conditional velocities. © 2015 Wiley Periodicals, Inc.

  15. Characterization of Medication Velocity and Size Distribution from Pressurized Metered-Dose Inhalers by Phase Doppler Anemometry.

    Science.gov (United States)

    Alatrash, Abubaker; Matida, Edgar

    2016-12-01

    Particle size and velocity are two of the most significant factors that impact the deposition of pressurized metered-dose inhaler (pMDI) sprays in the mouth cavity. pMDIs are prominently used around the world in the treatment of patients suffering from a variety of lung diseases such as asthma and chronic obstructive pulmonary disease. Since their introduction in the field, and as a result of their effectiveness and simplicity of usage, pMDIs are considered to be the most widely prescribed medical aerosol delivery system. In the current study, particle velocity and size distribution were measured at three different locations along the centerline of a pMDI spray using Phase Doppler Anemometry. pMDIs from four different pharmaceutical companies were tested, each using salbutamol sulfate as the medication. Measurements along at the pMDI centerline (at 0, 75, and 100 mm downstream of the inhaler mouthpiece) showed that the spray velocities were bimodal in time for all four pMDI brands. The first peak occurred as the spray was leaving the mouthpiece, while the second peak (at the same location, 0 mm) occurred at around 60, 95, 95, and 115 milliseconds later, respectively, for the four tested inhalers, with a drop in the velocity between the two peaks. Three probability density functions (PDFs) were tested, and the Rosin-Rammler PDF best fit the empirical data, as determined using a chi-squared test. These results suggest that there is a difference in the mean particle velocities at the centerline for the tested pMDIs and the diameter of released particles varied statistically for each brand.

  16. Extension de l'anémometrie phase Doppler à la mesure d'indice de réfraction et développement de la Vélocimétrie Laser par Corrélation

    OpenAIRE

    Hespel , Camille

    2007-01-01

    The aim of numerical and experimental study presented in this thesis is to improve optical diagnostics in order to understand the atomization and evaporation processes. The size-velocity correlation is diluted medium is given by Phase Doppler Anemometry.The objective of simultaions is to examine the possibilty to extend the PDA by refractive index measurement.The proposed extension called Glare Spot phase Doppler Anemometry is based on the analysis of glare points of reflection and refraction...

  17. The fractional virial potential energy in two-component systems

    Directory of Open Access Journals (Sweden)

    Caimmi R.

    2008-01-01

    Full Text Available Two-component systems are conceived as macrogases, and the related equation of state is expressed using the virial theorem for subsystems, under the restriction of homeoidally striated density profiles. Explicit calculations are performed for a useful reference case and a few cases of astrophysical interest, both with and without truncation radius. Shallower density profiles are found to yield an equation of state, φ = φ(y, m, characterized (for assigned values of the fractional mass, m = Mj /Mi by the occurrence of two extremum points, a minimum and a maximum, as found in an earlier attempt. Steeper density profiles produce a similar equation of state, which implies that a special value of m is related to a critical curve where the above mentioned extremum points reduce to a single horizontal inflexion point, and curves below the critical one show no extremum points. The similarity of the isofractional mass curves to van der Waals' isothermal curves, suggests the possibility of a phase transition in a bell-shaped region of the (Oyφ plane, where the fractional truncation radius along a selected direction is y = Rj /Ri , and the fractional virial potential energy is φ = (Eji vir /(Eij vir . Further investigation is devoted to mass distributions described by Hernquist (1990 density profiles, for which an additional relation can be used to represent a sample of N = 16 elliptical galaxies (EGs on the (Oyφ plane. Even if the evolution of elliptical galaxies and their hosting dark matter (DM haloes, in the light of the model, has been characterized by equal fractional mass, m, and equal scaled truncation radius, or concentration, Ξu = Ru /r† , u = i, j, still it cannot be considered as strictly homologous, due to different values of fractional truncation radii, y, or fractional scaling radii, y† = r† /r† , deduced from sample objects.

  18. Reduction of phase-induced intensity noise in a fiber-based coherent Doppler lidar using polarization control

    DEFF Research Database (Denmark)

    Rodrigo, Peter John; Pedersen, Christian

    2010-01-01

    Optimization of signal-to-noise ratio is an important aspect in the design of optical heterodyne detection systems such as a coherent Doppler lidar (CDL). In a CDL, optimal performance is achieved when the noise in the detector signal is dominated by local oscillator shot-noise. Most modern CDL...... systems are built using rugged and cost-efficient fiber optic components. Unfortunately, leakage signals such as residual reflections inherent within fiber components (e.g. circulator) can introduce phaseinduced intensity noise (PIIN) to the Doppler spectrum in a CDL. Such excess noise may be a few orders...

  19. The chemistry of two-component fluoride crystalline optical media for heavy, fast, radiation hard scintillators

    International Nuclear Information System (INIS)

    Sobolev, B.P.; Krivandina, E.A.; Fedorov, P.P.; Vasilchenko, V.G.

    1994-01-01

    Prospects for preparation of two-component dense optical materials for scintillators are shown, using data on phase diagrams of about 300 MF m - RF n (m, n ≤ 4) type systems, formed by metal fluorides. Primary characteristics (decay time and light output of luminescence, radiation hardness, etc.) of some multicomponent crystals are reported

  20. Two component micro injection moulding for moulded interconnect devices

    DEFF Research Database (Denmark)

    Islam, Aminul

    2008-01-01

    Moulded interconnect devices (MIDs) contain huge possibilities for many applications in micro electro-mechanical-systems because of their capability of reducing the number of components, process steps and finally in miniaturization of the product. Among the available MID process chains, two...... component injection moulding is one of the most industrially adaptive processes. However, the use of two component injection moulding for MID fabrication, with circuit patterns in the sub-millimeter range, is still a big challenge at the present state of technology. The scope of the current Ph.D. project...... and a reasonable adhesion between them. • Selective metallization of the two component plastic part (coating one polymer with metal and leaving the other one uncoated) To overcome these two main issues in MID fabrication for micro applications, the current Ph.D. project explores the technical difficulties...

  1. Two-component feedback loops and deformed mechanics

    International Nuclear Information System (INIS)

    Tourigny, David S.

    2015-01-01

    It is shown that a general two-component feedback loop can be viewed as a deformed Hamiltonian system. Some of the implications of using ideas from theoretical physics to study biological processes are discussed. - Highlights: • Two-component molecular feedback loops are viewed as q-deformed Hamiltonian systems. • Deformations are reversed using Jackson derivatives to take advantage of working in the Hamiltonian limit. • New results are derived for the particular examples considered. • General deformations are suggested to be associated with a broader class of biological processes

  2. The Fractional Virial Potential Energy in Two-Component Systems

    Directory of Open Access Journals (Sweden)

    Caimmi, R.

    2008-12-01

    Full Text Available Two-component systems are conceived as macrogases, and the related equation of state is expressed using the virial theorem for subsystems, under the restriction of homeoidally striated density profiles. Explicit calculations are performed for a useful reference case and a few cases of astrophysical interest, both with and without truncation radius. Shallower density profiles are found to yield an equation of state, $phi=phi(y,m$, characterized (for assigned values of the fractional mass, $m=M_j/ M_i$ by the occurrence of two extremum points, a minimum and a maximum, as found in an earlier attempt. Steeper density profiles produce a similar equation of state, which implies that a special value of $m$ is related to a critical curve where the above mentioned extremum points reduce to a single horizontal inflexion point, and curves below the critical one show no extremum points. The similarity of the isofractional mass curves to van der Waals' isothermal curves, suggests the possibility of a phase transition in a bell-shaped region of the $({sf O}yphi$ plane, where the fractional truncation radius along a selected direction is $y=R_j/R_i$, and the fractional virial potential energy is $phi=(E_{ji}_mathrm{vir}/(E_{ij}_mathrm{vir}$. Further investigation is devoted to mass distributions described by Hernquist (1990 density profiles, for which an additional relation can be used to represent a sample of $N=16$ elliptical galaxies (EGs on the $({sf O}yphi$ plane. Even if the evolution of elliptical galaxies and their hosting dark matter (DM haloes, in the light of the model, has been characterized by equal fractional mass, $m$, and equal scaled truncation radius, or concentration, $Xi_u=R_u/r_u^dagger$, $u=i,j$, still it cannot be considered as strictly homologous, due to different values of fractional truncation radii, $y$, or fractional scaling radii, $y^dagger=r_j^dagger/r_i^dagger$, deduced from sample objects.

  3. Synthesis and Characterization of Two Component Alloy Nanoparticles

    Science.gov (United States)

    Tabatabaei, Salomeh

    Alloying is an old trick used to produce new materials by synergistically combining at least two components. New developments in nanoscience have enabled new degrees of freedom, such as size, solubility and concentration of the alloying element to be utilized in the design of the physical properties of alloy nanoparticles (ANPs). ANPs as multi-functional materials have applications in catalysis, biomedical technologies and electronics. Phase diagrams of ANPs are very little known and may not represent that of bulk picture, furthermore, ANPs with different crystallite orientation and compositions could remain far from equilibrium. Here, we studied the synthesis and stability of Au-Sn and Ag-Ni ANPs with chemical reduction method at room temperature. Due to the large difference in the redox potentials of Au and Sn, co-reduction is not a reproducible method. However, two step successive reductions was found to be more reliable to generate Au-Sn ANPs which consists of forming clusters in the first step (either without capping agent or with weakly coordinated surfactant molecules) and then undergoing a second reduction step in the presence of another metal salt. Our observation also showed that capping agents (Cetrimonium bromide or (CTAB)) and Polyacrylic acid (PAA)) play a key role in the alloying process and shorter length capping agent (PAA) may facilitate the diffusion of individual components and thus enabling better alloying. Different molar ratios of Sn and Au precursors were used to study the effect of alloying elements on the melting point and the crystalline structures and melting points were determined by various microscopy and spectroscopy techniques and differential scanning calorimetry (DSC). A significant depression (up to150°C) in the melting transition was observed for the Au-Sn ANPs compared to the bulk eutectic point (Tm 280°C) due to the size and shape effect. Au-Sn ANPs offer a unique set of advantages as lead-free solder material which can

  4. A two-component NZRI metamaterial based rectangular cloak

    Directory of Open Access Journals (Sweden)

    Sikder Sunbeam Islam

    2015-10-01

    Full Text Available A new two-component, near zero refractive index (NZRI metamaterial is presented for electromagnetic rectangular cloaking operation in the microwave range. In the basic design a pi-shaped, metamaterial was developed and its characteristics were investigated for the two major axes (x and z-axis wave propagation through the material. For the z-axis wave propagation, it shows more than 2 GHz bandwidth and for the x-axis wave propagation; it exhibits more than 1 GHz bandwidth of NZRI property. The metamaterial was then utilized in designing a rectangular cloak where a metal cylinder was cloaked perfectly in the C-band area of microwave regime. The experimental result was provided for the metamaterial and the cloak and these results were compared with the simulated results. This is a novel and promising design for its two-component NZRI characteristics and rectangular cloaking operation in the electromagnetic paradigm.

  5. Brazilian two-component TLD albedo neutron individual monitoring system

    Energy Technology Data Exchange (ETDEWEB)

    Martins, M.M., E-mail: marcelo@ird.gov.b [Instituto de Radioprotecao e Dosimetria (IRD), Av. Salvador Allende, s/n, CEP: 22780-160, Rio de Janeiro, RJ (Brazil); Mauricio, C.L.P., E-mail: claudia@ird.gov.b [Instituto de Radioprotecao e Dosimetria (IRD), Av. Salvador Allende, s/n, CEP: 22780-160, Rio de Janeiro, RJ (Brazil); Fonseca, E.S. da, E-mail: evaldo@ird.gov.b [Instituto de Radioprotecao e Dosimetria (IRD), Av. Salvador Allende, s/n, CEP: 22780-160, Rio de Janeiro, RJ (Brazil); Silva, A.X. da, E-mail: ademir@con.ufrj.b [Coordenacao dos Programas de Pos-Graduacao em Engenharia, COPPE/PEN Caixa Postal 68509, CEP: 21941-972, Rio de Janeiro, RJ (Brazil)

    2010-12-15

    Since 1983, Instituto de Radioprotecao e Dosimetria, Brazil, uses a TLD one-component albedo neutron monitor, which has a single different calibration factor specifically for each installation type. In order to improve its energy response, a two-component albedo monitor was developed, which measure the thermal neutron component besides the albedo one. The two-component monitor has been calibrated in reference neutron fields: thermal, five accelerator-produced monoenergetic beams (70, 144, 565, 1200 and 5000 keV) and five radionuclide sources ({sup 252}Cf, {sup 252}Cf(D{sub 2}O), {sup 241}Am-Be, {sup 241}Am-B and {sup 238}Pu-Be) at several distances. Since January 2008, mainly Brazilian workers who handle neutron sources at different distances and moderation, such as in well logging and calibration facilities are using it routinely.

  6. On the Alexander polynominals of alternating two-component links

    Directory of Open Access Journals (Sweden)

    Mark E. Kidwell

    1979-01-01

    Full Text Available Let L be an alternating two-component link with Alexander polynomial Δ(x,y. Then the polynomials (1−xΔ(x,y and (1−yΔ(x,y are alternating. That is, (1−yΔ(x,y can be written as ∑i,jcijxiyj in such a way that (−1i+jcij≥0.

  7. Two-component gravitational instability in spiral galaxies

    Science.gov (United States)

    Marchuk, A. A.; Sotnikova, N. Y.

    2018-04-01

    We applied a criterion of gravitational instability, valid for two-component and infinitesimally thin discs, to observational data along the major axis for seven spiral galaxies of early types. Unlike most papers, the dispersion equation corresponding to the criterion was solved directly without using any approximation. The velocity dispersion of stars in the radial direction σR was limited by the range of possible values instead of a fixed value. For all galaxies, the outer regions of the disc were analysed up to R ≤ 130 arcsec. The maximal and sub-maximal disc models were used to translate surface brightness into surface density. The largest destabilizing disturbance stars can exert on a gaseous disc was estimated. It was shown that the two-component criterion differs a little from the one-fluid criterion for galaxies with a large surface gas density, but it allows to explain large-scale star formation in those regions where the gaseous disc is stable. In the galaxy NGC 1167 star formation is entirely driven by the self-gravity of the stars. A comparison is made with the conventional approximations which also include the thickness effect and with models for different sound speed cg. It is shown that values of the effective Toomre parameter correspond to the instability criterion of a two-component disc Qeff < 1.5-2.5. This result is consistent with previous theoretical and observational studies.

  8. Two-component scattering model and the electron density spectrum

    Science.gov (United States)

    Zhou, A. Z.; Tan, J. Y.; Esamdin, A.; Wu, X. J.

    2010-02-01

    In this paper, we discuss a rigorous treatment of the refractive scintillation caused by a two-component interstellar scattering medium and a Kolmogorov form of density spectrum. It is assumed that the interstellar scattering medium is composed of a thin-screen interstellar medium (ISM) and an extended interstellar medium. We consider the case that the scattering of the thin screen concentrates in a thin layer represented by a δ function distribution and that the scattering density of the extended irregular medium satisfies the Gaussian distribution. We investigate and develop equations for the flux density structure function corresponding to this two-component ISM geometry in the scattering density distribution and compare our result with the observations. We conclude that the refractive scintillation caused by this two-component ISM scattering gives a more satisfactory explanation for the observed flux density variation than does the single extended medium model. The level of refractive scintillation is strongly sensitive to the distribution of scattering material along the line of sight (LOS). The theoretical modulation indices are comparatively less sensitive to the scattering strength of the thin-screen medium, but they critically depend on the distance from the observer to the thin screen. The logarithmic slope of the structure function is sensitive to the scattering strength of the thin-screen medium, but is relatively insensitive to the thin-screen location. Therefore, the proposed model can be applied to interpret the structure functions of flux density observed in pulsar PSR B2111 + 46 and PSR B0136 + 57. The result suggests that the medium consists of a discontinuous distribution of plasma turbulence embedded in the interstellar medium. Thus our work provides some insight into the distribution of the scattering along the LOS to the pulsar PSR B2111 + 46 and PSR B0136 + 57.

  9. A two-component copula with links to insurance

    Directory of Open Access Journals (Sweden)

    Ismail S.

    2017-12-01

    Full Text Available This paper presents a new copula to model dependencies between insurance entities, by considering how insurance entities are affected by both macro and micro factors. The model used to build the copula assumes that the insurance losses of two companies or lines of business are related through a random common loss factor which is then multiplied by an individual random company factor to get the total loss amounts. The new two-component copula is not Archimedean and it extends the toolkit of copulas for the insurance industry.

  10. Two component micro injection molding for MID fabrication

    DEFF Research Database (Denmark)

    Islam, Mohammad Aminul; Hansen, Hans Nørgaard; Tang, Peter Torben

    2009-01-01

    Molded Interconnect Devices (MIDs) are plastic substrates with electrical infrastructure. The fabrication of MIDs is usually based on injection molding and different process chains may be identified from this starting point. The use of MIDs has been driven primarily by the automotive sector......, but recently the medical sector seems more and more interested. In particular the possibility of miniaturization of 3D components with electrical infrastructure is attractive. The paper describes possible manufacturing routes and challenges of miniaturized MIDs based on two component micro injection molding...

  11. Characterisation of an airblast sputtering unit - verification of numeric simulations using an adapted phase doppler droplet measuring technique; Charakterisierung eines Airblastzerstaeubers - Bestaetigung numerischer Simulationen mit einem angepassten Phasen-Doppler-Tropfenmessverfahren

    Energy Technology Data Exchange (ETDEWEB)

    Willmann, M.

    1999-07-01

    Two-phase flows were investigated in high-pressure conditions in order to assess the influence of pressure and temperature on spray jet dispersion in so-called airblast sputtering units, whose function is described. The project was to contribute to improved characterisation and better understanding of spray jets. New methods of measurement and calculation were employed that provide more comprehensive and accurate data on two-phase flows. [German] In der vorliegenden Arbeit sollen Zweiphasenstroemungen unter Hochdruckbedingungen untersucht werden, um den Einfluss von Druck und Temperatur auf die Spruehstrahl-Ausbreitung unter Verwendung von sogenannten Airblast-Zerstaeubern aufzuzeigen. Diese Zerstaeuberbauart wird derzeit typischerweise in Gasturbinen eingesetzt, ihre Funktionsweise wird in einem Kapitel der Arbeit dargestellt. Mit der vorliegenden Arbeit wird ein wesentlicher Beitrag zur verbesserten Charakterisierung und zum erweiterten Verstaendnis von Spruehstrahlen, insbesondere unter Einsatz von Airblast-Zerstaeubern geschaffen. Dabei werden sowohl im messtechnischen Bereich wie auch auf numerischer Seite neue Methoden vorgestellt, die eine wesentlich umfassendere und genauere Darstellung von Zweiphasenstroemungen erlauben. Der Einsatz dieser erweiterten Methoden an der Stroemung eines Modellairblastzerstaeubers zeigt wichtige Effekte bei der Tropfenausbreitung und -verdunstung auf. Die Arbeit ist dabei in drei Teilbereiche gegliedert. In einem messtechnisch ausgerichteten Teil werden die neuen, erweiterten Ansaetze zur Auslegung des Phasen-Doppler Verfahrens vorgestellt und damit die Grundlagen zur experimentellen Charakterisierung eines Spruehstrahls geschaffen. In zweiten Teil erfolgt die Darstellung der verwendeten numerischen Methoden. Im dritten Teil werden schliesslich die Resultate experimenteller wie numerischer Untersuchungen parallel eingesetzt, um die physikalischen Phaenomene im Spruehstrahl eines Airblastzerstaeubers darzustellen und damit die

  12. Numerical analysis of a non equilibrium two-component two-compressible flow in porous media

    KAUST Repository

    Saad, Bilal Mohammed

    2013-09-01

    We propose and analyze a finite volume scheme to simulate a non equilibrium two components (water and hydrogen) two phase flow (liquid and gas) model. In this model, the assumption of local mass non equilibrium is ensured and thus the velocity of the mass exchange between dissolved hydrogen and hydrogen in the gas phase is supposed finite. The proposed finite volume scheme is fully implicit in time together with a phase-by-phase upwind approach in space and it is discretize the equations in their general form with gravity and capillary terms We show that the proposed scheme satisfies the maximum principle for the saturation and the concentration of the dissolved hydrogen. We establish stability results on the velocity of each phase and on the discrete gradient of the concentration. We show the convergence of a subsequence to a weak solution of the continuous equations as the size of the discretization tends to zero. At our knowledge, this is the first convergence result of finite volume scheme in the case of two component two phase compressible flow in several space dimensions.

  13. Non-Contact Sensor for Long-Term Continuous Vital Signs Monitoring: A Review on Intelligent Phased-Array Doppler Sensor Design.

    Science.gov (United States)

    Hall, Travis; Lie, Donald Y C; Nguyen, Tam Q; Mayeda, Jill C; Lie, Paul E; Lopez, Jerry; Banister, Ron E

    2017-11-15

    It has been the dream of many scientists and engineers to realize a non-contact remote sensing system that can perform continuous, accurate and long-term monitoring of human vital signs as we have seen in many Sci-Fi movies. Having an intelligible sensor system that can measure and record key vital signs (such as heart rates and respiration rates) remotely and continuously without touching the patients, for example, can be an invaluable tool for physicians who need to make rapid life-and-death decisions. Such a sensor system can also effectively help physicians and patients making better informed decisions when patients' long-term vital signs data is available. Therefore, there has been a lot of research activities on developing a non-contact sensor system that can monitor a patient's vital signs and quickly transmit the information to healthcare professionals. Doppler-based radio-frequency (RF) non-contact vital signs (NCVS) monitoring system are particularly attractive for long term vital signs monitoring because there are no wires, electrodes, wearable devices, nor any contact-based sensors involved so the subjects may not be even aware of the ubiquitous monitoring. In this paper, we will provide a brief review on some latest development on NCVS sensors and compare them against a few novel and intelligent phased-array Doppler-based RF NCVS biosensors we have built in our labs. Some of our NCVS sensor tests were performed within a clutter-free anechoic chamber to mitigate the environmental clutters, while most tests were conducted within the typical Herman-Miller type office cubicle setting to mimic a more practical monitoring environment. Additionally, we will show the measurement data to demonstrate the feasibility of long-term NCVS monitoring. The measured data strongly suggests that our latest phased array NCVS system should be able to perform long-term vital signs monitoring intelligently and robustly, especially for situations where the subject is sleeping

  14. Disorder-Induced Order in Two-Component Bose-Einstein Condensates

    International Nuclear Information System (INIS)

    Niederberger, A.; Schulte, T.; Wehr, J.; Lewenstein, M.; Sanchez-Palencia, L.; Sacha, K.

    2008-01-01

    We propose and analyze a general mechanism of disorder-induced order in two-component Bose-Einstein condensates, analogous to corresponding effects established for XY spin models. We show that a random Raman coupling induces a relative phase of π/2 between the two BECs and that the effect is robust. We demonstrate it in one, two, and three dimensions at T=0 and present evidence that it persists at small T>0. Applications to phase control in ultracold spinor condensates are discussed

  15. Three-wave interaction in two-component quadratic nonlinear lattices

    DEFF Research Database (Denmark)

    Konotop, V. V.; Cunha, M. D.; Christiansen, Peter Leth

    1999-01-01

    We investigate a two-component lattice with a quadratic nonlinearity and find with the multiple scale technique that integrable three-wave interaction takes place between plane wave solutions when these fulfill resonance conditions. We demonstrate that. energy conversion and pulse propagation known...... from three-wave interaction is reproduced in the lattice and that exact phase matching of parametric processes can be obtained in non-phase-matched lattices by tilting the interacting plane waves with respect to each other. [S1063-651X(99)15110-9]....

  16. Efficient implementation of one- and two-component analytical energy gradients in exact two-component theory

    Science.gov (United States)

    Franzke, Yannick J.; Middendorf, Nils; Weigend, Florian

    2018-03-01

    We present an efficient algorithm for one- and two-component analytical energy gradients with respect to nuclear displacements in the exact two-component decoupling approach to the one-electron Dirac equation (X2C). Our approach is a generalization of the spin-free ansatz by Cheng and Gauss [J. Chem. Phys. 135, 084114 (2011)], where the perturbed one-electron Hamiltonian is calculated by solving a first-order response equation. Computational costs are drastically reduced by applying the diagonal local approximation to the unitary decoupling transformation (DLU) [D. Peng and M. Reiher, J. Chem. Phys. 136, 244108 (2012)] to the X2C Hamiltonian. The introduced error is found to be almost negligible as the mean absolute error of the optimized structures amounts to only 0.01 pm. Our implementation in TURBOMOLE is also available within the finite nucleus model based on a Gaussian charge distribution. For a X2C/DLU gradient calculation, computational effort scales cubically with the molecular size, while storage increases quadratically. The efficiency is demonstrated in calculations of large silver clusters and organometallic iridium complexes.

  17. Zero-range approximation for two-component boson systems

    International Nuclear Information System (INIS)

    Sogo, T.; Fedorov, D.V.; Jensen, A.S.

    2005-01-01

    The hyperspherical adiabatic expansion method is combined with the zero-range approximation to derive angular Faddeev-like equations for two-component boson systems. The angular eigenvalues are solutions to a transcendental equation obtained as a vanishing determinant of a 3 x 3 matrix. The eigenfunctions are linear combinations of Jacobi functions of argument proportional to the distance between pairs of particles. We investigate numerically the influence of two-body correlations on the eigenvalue spectrum, the eigenfunctions and the effective hyperradial potential. Correlations decrease or increase the distance between pairs for effectively attractive or repulsive interactions, respectively. New structures appear for non-identical components. Fingerprints can be found in the nodal structure of the density distributions of the condensates. (author)

  18. How insects overcome two-component plant chemical defence

    DEFF Research Database (Denmark)

    Pentzold, Stefan; Zagrobelny, Mika; Rook, Frederik

    2014-01-01

    Insect herbivory is often restricted by glucosylated plant chemical defence compounds that are activated by plant β-glucosidases to release toxic aglucones upon plant tissue damage. Such two-component plant defences are widespread in the plant kingdom and examples of these classes of compounds...... are alkaloid, benzoxazinoid, cyanogenic and iridoid glucosides as well as glucosinolates and salicinoids. Conversely, many insects have evolved a diversity of counteradaptations to overcome this type of constitutive chemical defence. Here we discuss that such counter-adaptations occur at different time points......, before and during feeding as well as during digestion, and at several levels such as the insects’ feeding behaviour, physiology and metabolism. Insect adaptations frequently circumvent or counteract the activity of the plant β-glucosidases, bioactivating enzymes that are a key element in the plant’s two...

  19. Bond strength of two component injection moulded MID

    DEFF Research Database (Denmark)

    Islam, Mohammad Aminul; Hansen, Hans Nørgaard; Tang, Peter Torben

    2006-01-01

    Most products of the future will require industrially adapted, cost effective production processes and on this issue two-component (2K) injection moulding is a potential candidate for MID manufacturing. MID based on 2k injection moulded plastic part with selectively metallised circuit tracks allows...... the two different plastic materials in the MID structure require good bonding between them. This paper finds suitable combinations of materials for MIDs from both bond strength and metallisation view-point. Plastic parts were made by two-shot injection moulding and the effects of some important process...... the integration of electrical and mechanical functionalities in a real 3D structure. If 2k injection moulding is applied with two polymers, of which one is plateable and the other is not, it will be possible to make 3D electrical structures directly on the component. To be applicable in the real engineering field...

  20. Two Component Injection Moulding for Moulded Interconnect Devices

    DEFF Research Database (Denmark)

    Islam, Aminul

    component (2k) injection moulding is one of the most industrially adaptive processes. However, the use of two component injection moulding for MID fabrication, with circuit patterns in sub-millimeter range, is still a big challenge. This book searches for the technical difficulties associated...... with the process and makes attempts to overcome those challenges. In search of suitable polymer materials for MID applications, potential materials are characterized in terms of polymer-polymer bond strength, polymer-polymer interface quality and selective metallization. The experimental results find the factors...... which can effectively control the quality of 2k moulded parts and metallized MIDs. This book presents documented knowledge about MID process chains, 2k moulding and selective metallization which can be valuable source of information for both academic and industrial users....

  1. Phosphatase activity tunes two-component system sensor detection threshold.

    Science.gov (United States)

    Landry, Brian P; Palanki, Rohan; Dyulgyarov, Nikola; Hartsough, Lucas A; Tabor, Jeffrey J

    2018-04-12

    Two-component systems (TCSs) are the largest family of multi-step signal transduction pathways in biology, and a major source of sensors for biotechnology. However, the input concentrations to which biosensors respond are often mismatched with application requirements. Here, we utilize a mathematical model to show that TCS detection thresholds increase with the phosphatase activity of the sensor histidine kinase. We experimentally validate this result in engineered Bacillus subtilis nitrate and E. coli aspartate TCS sensors by tuning their detection threshold up to two orders of magnitude. We go on to apply our TCS tuning method to recently described tetrathionate and thiosulfate sensors by mutating a widely conserved residue previously shown to impact phosphatase activity. Finally, we apply TCS tuning to engineer B. subtilis to sense and report a wide range of fertilizer concentrations in soil. This work will enable the engineering of tailor-made biosensors for diverse synthetic biology applications.

  2. Two-component multistep direct reactions: A microscopic approach

    International Nuclear Information System (INIS)

    Koning, A.J.; Chadwick, M.B.

    1998-03-01

    The authors present two principal advances in multistep direct theory: (1) A two-component formulation of multistep direct reactions, where neutron and proton excitations are explicitly accounted for in the evolution of the reaction, for all orders of scattering. While this may at first seem to be a formidable task, especially for multistep processes where the many possible reaction pathways becomes large in a two-component formalism, the authors show that this is not so -- a rather simple generalization of the FKK convolution expression 1 automatically generates these pathways. Such considerations are particularly relevant when simultaneously analyzing both neutron and proton emission spectra, which is always important since these processes represent competing decay channels. (2) A new, and fully microscopic, method for calculating MSD cross sections which does not make use of particle-hole state densities but instead directly calculates cross sections for all possible particle-hole excitations (again including an exact book-keeping of the neutron/proton type of the particle and hole at all stages of the reaction) determined from a simple non-interacting shell model. This is in contrast to all previous numerical approaches which sample only a small number of such states to estimate the DWBA strength, and utilize simple analytical formulae for the partial state density, based on the equidistant spacing model. The new approach has been applied, along with theories for multistep compound, compound, and collective reactions, to analyze experimental emission spectra for a range of targets and energies. The authors show that the theory correctly accounts for double-differential nucleon spectra

  3. Global existence and blow-up phenomena for two-component Degasperis-Procesi system and two-component b-family system

    OpenAIRE

    Liu, Jingjing; Yin, Zhaoyang

    2014-01-01

    This paper is concerned with global existence and blow-up phenomena for two-component Degasperis-Procesi system and two-component b-family system. The strategy relies on our observation on new conservative quantities of these systems. Several new global existence results and a new blowup result of strong solutions to the two-component Degasperis- Procesi system and the two-component b-family system are presented by using these new conservative quantities.

  4. A minimal model for two-component dark matter

    International Nuclear Information System (INIS)

    Esch, Sonja; Klasen, Michael; Yaguna, Carlos E.

    2014-01-01

    We propose and study a new minimal model for two-component dark matter. The model contains only three additional fields, one fermion and two scalars, all singlets under the Standard Model gauge group. Two of these fields, one fermion and one scalar, are odd under a Z_2 symmetry that renders them simultaneously stable. Thus, both particles contribute to the observed dark matter density. This model resembles the union of the singlet scalar and the singlet fermionic models but it contains some new features of its own. We analyze in some detail its dark matter phenomenology. Regarding the relic density, the main novelty is the possible annihilation of one dark matter particle into the other, which can affect the predicted relic density in a significant way. Regarding dark matter detection, we identify a new contribution that can lead either to an enhancement or to a suppression of the spin-independent cross section for the scalar dark matter particle. Finally, we define a set of five benchmarks models compatible with all present bounds and examine their direct detection prospects at planned experiments. A generic feature of this model is that both particles give rise to observable signals in 1-ton direct detection experiments. In fact, such experiments will be able to probe even a subdominant dark matter component at the percent level.

  5. Exploring a minimal two-component p53 model

    International Nuclear Information System (INIS)

    Sun, Tingzhe; Zhu, Feng; Shen, Pingping; Yuan, Ruoshi; Xu, Wei

    2010-01-01

    The tumor suppressor p53 coordinates many attributes of cellular processes via interlocked feedback loops. To understand the biological implications of feedback loops in a p53 system, a two-component model which encompasses essential feedback loops was constructed and further explored. Diverse bifurcation properties, such as bistability and oscillation, emerge by manipulating the feedback strength. The p53-mediated MDM2 induction dictates the bifurcation patterns. We first identified irradiation dichotomy in p53 models and further proposed that bistability and oscillation can behave in a coordinated manner. Further sensitivity analysis revealed that p53 basal production and MDM2-mediated p53 degradation, which are central to cellular control, are most sensitive processes. Also, we identified that the much more significant variations in amplitude of p53 pulses observed in experiments can be derived from overall amplitude parameter sensitivity. The combined approach with bifurcation analysis, stochastic simulation and sampling-based sensitivity analysis not only gives crucial insights into the dynamics of the p53 system, but also creates a fertile ground for understanding the regulatory patterns of other biological networks

  6. Parameter studies for a two-component fusion experiment

    International Nuclear Information System (INIS)

    Towner, H.H.

    1975-01-01

    The sensitivity of the energy multiplication of a two-component fusion experiment is examined relative to the following parameters: energy confinement time (tau/sub E/), particle confinement time (tau/sub p/), effective Z of the plasma (Z/sub eff/), injection rate (j/sub I/) and injection energy (E/sub I/). The Energy Research and Development Administration recently approved funding for such a fusion device (the Toroidal Fusion Test Reactor or TFTR) which will be built at the Princeton Plasma Physics Laboratory. Hence, such a parameter study seems both timely and necessary. This work also serves as an independent check on the design values proposed for the TFTR to enable it to achieve energy breakeven (F = 1). Using the nominal TFTR design parameters and a self-consistent ion-electron power balance, the maximum F-value is found to be approximately 1.2 which occurs at an injection energy of approximately 210 KeV. The injector operation, i.e. its current and energy capability are shown to be a very critical factor in the TFTR performance. However, if the injectors meet the design objectives, there appears to be sufficient latitude in the other parameters to offer reasonable assurance that energy breakeven can be achieved. (U.S.)

  7. Composite fermion basis for two-component Bose gases

    Science.gov (United States)

    Meyer, Marius; Liabotro, Ola

    The composite fermion (CF) construction is known to produce wave functions that are not necessarily orthogonal, or even linearly independent, after projection. While usually not a practical issue in the quantum Hall regime, we have previously shown that it presents a technical challenge for rotating Bose gases with low angular momentum. These are systems where the CF approach yield surprisingly good approximations to the exact eigenstates of weak short-range interactions, and so solving the problem of linearly dependent wave functions is of interest. It can also be useful for studying CF excitations for fermions. Here we present several ways of constructing a basis for the space of ``simple CF states'' for two-component rotating Bose gases in the lowest Landau level, and prove that they all give a basis. Using the basis, we study the structure of the lowest-lying state using so-called restricted wave functions. We also examine the scaling of the overlap between the exact and CF wave functions at the maximal possible angular momentum for simple states. This work was financially supported by the Research Council of Norway.

  8. Cold component flow in a two-component mirror machine

    International Nuclear Information System (INIS)

    Rognlien, T.D.

    1975-12-01

    Steady-state solutions are given for the flow characteristics along the magnetic field of the cold plasma component in a two-component mirror machine. The hot plasma component is represented by a fixed density profile. The fluid equations are used to describe the cold plasma, which is assumed to be generated in a localized region at one end of the machine. The ion flow speed, v/sub i/, is required to satisfy the Bohm sheath condition at the end walls, i.e., v/sub i/ greater than or equal to c/sub s/, where c/sub s/ is the ion-acoustic speed. For the case when the cold plasma density, n/sub c/, is much less than the hot plasma density, n/sub h/, the cold plasma is stagnant and does not penetrate through the machine in the zero temperature case. The effect of a finite temperature is to allow for the penetration of a small amount of cold plasma through the machine. For the density range n/sub c/ approximately n/sub h/, the flow solutions are asymmetric about the midplane and have v/sub i/ = c/sub s/ near the midplane. Finally, for n/sub c/ much greater than n/sub h/, the solutions become symmetric about the midplane and approach the Lee--McNamara type solutions with v/sub i/ = c/sub s/ near the mirror throats

  9. Fast-wave heating of a two-component plasma

    International Nuclear Information System (INIS)

    Stix, T.H.

    1975-02-01

    The use of the compressional hydromagnetic mode (also called the magnetosonic or, simply, the fast wave) is examined in some detail with respect to the heating of a tritium plasma containing a few percent deuterium. Efficient absorption of wave energy by the deuteron component is found when ω = ω/sub c/ (deuterons), with Q/sub wave/ greater than or equal to 100. The dominant behavior of the high-energy deuteron distribution function is found to be f(v) approximately exp[3/2) ∫/sup v/ dv less than Δv greater than/less than(Δv/sub perpendicular to/) 2 greater than], where [Δv] is the Chandrasekhar-Spitzer drag coefficient, and [(Δv/sub perpendicular to/) 2 sigma] is the Kennel-Englemann quasilinear diffusion coefficient for wave--particle interaction at the deuteron cyclotron frequency. An analytic solution to the one-dimensional Fokker--Planck equation, with rf-induced diffusion, is developed, and using this solution together with Duane's fit to the D-T fusion cross-section, it is found that the nuclear fusion power output from an rf-produced two-component plasma can significantly exceed the incremental (radiofrequency) power input. (auth)

  10. Implementation of two-component advective flow solution in XSPEC

    Science.gov (United States)

    Debnath, Dipak; Chakrabarti, Sandip K.; Mondal, Santanu

    2014-05-01

    Spectral and temporal properties of black hole candidates can be explained reasonably well using Chakrabarti-Titarchuk solution of two-component advective flow (TCAF). This model requires two accretion rates, namely the Keplerian disc accretion rate and the halo accretion rate, the latter being composed of a sub-Keplerian, low-angular-momentum flow which may or may not develop a shock. In this solution, the relevant parameter is the relative importance of the halo (which creates the Compton cloud region) rate with respect to the Keplerian disc rate (soft photon source). Though this model has been used earlier to manually fit data of several black hole candidates quite satisfactorily, for the first time, we made it user friendly by implementing it into XSPEC software of Goddard Space Flight Center (GSFC)/NASA. This enables any user to extract physical parameters of the accretion flows, such as two accretion rates, the shock location, the shock strength, etc., for any black hole candidate. We provide some examples of fitting a few cases using this model. Most importantly, unlike any other model, we show that TCAF is capable of predicting timing properties from the spectral fits, since in TCAF, a shock is responsible for deciding spectral slopes as well as quasi-periodic oscillation frequencies. L86

  11. Light-front QCD. II. Two-component theory

    International Nuclear Information System (INIS)

    Zhang, W.; Harindranath, A.

    1993-01-01

    The light-front gauge A a + =0 is known to be a convenient gauge in practical QCD calculations for short-distance behavior, but there are persistent concerns about its use because of its ''singular'' nature. The study of nonperturbative field theory quantizing on a light-front plane for hadronic bound states requires one to gain a priori systematic control of such gauge singularities. In the second paper of this series we study the two-component old-fashioned perturbation theory and various severe infrared divergences occurring in old-fashioned light-front Hamiltonian calculations for QCD. We also analyze the ultraviolet divergences associated with a large transverse momentum and examine three currently used regulators: an explicit transverse cutoff, transverse dimensional regularization, and a global cutoff. We discuss possible difficulties caused by the light-front gauge singularity in the applications of light-front QCD to both old-fashioned perturbative calculations for short-distance physics and upcoming nonperturbative investigations for hadronic bound states

  12. 4-D flow magnetic resonance imaging: blood flow quantification compared to 2-D phase-contrast magnetic resonance imaging and Doppler echocardiography

    Energy Technology Data Exchange (ETDEWEB)

    Gabbour, Maya [Ann and Robert H. Lurie Children' s Hospital of Chicago, Department of Medical Imaging 9, Chicago, IL (United States); Schnell, Susanne [Northwestern University Feinberg School of Medicine, Department of Radiology, Chicago, IL (United States); Jarvis, Kelly [Northwestern University, Department of Biomedical Engineering, McCormick School of Engineering, Evanston, IL (United States); Robinson, Joshua D. [Ann and Robert H. Lurie Children' s Hospital of Chicago, Department of Pediatrics, Division of Pediatric Cardiology, Chicago, IL (United States); Northwestern University Feinberg School of Medicine, Department of Pediatrics, Chicago, IL (United States); Markl, Michael [Northwestern University Feinberg School of Medicine, Department of Radiology, Chicago, IL (United States); Northwestern University, Department of Biomedical Engineering, McCormick School of Engineering, Evanston, IL (United States); Rigsby, Cynthia K. [Ann and Robert H. Lurie Children' s Hospital of Chicago, Department of Medical Imaging 9, Chicago, IL (United States); Northwestern University Feinberg School of Medicine, Department of Radiology, Chicago, IL (United States)

    2015-06-15

    Doppler echocardiography (echo) is the reference standard for blood flow velocity analysis, and two-dimensional (2-D) phase-contrast magnetic resonance imaging (MRI) is considered the reference standard for quantitative blood flow assessment. However, both clinical standard-of-care techniques are limited by 2-D acquisitions and single-direction velocity encoding and may make them inadequate to assess the complex three-dimensional hemodynamics seen in congenital heart disease. Four-dimensional flow MRI (4-D flow) enables qualitative and quantitative analysis of complex blood flow in the heart and great arteries. The objectives of this study are to compare 4-D flow with 2-D phase-contrast MRI for quantification of aortic and pulmonary flow and to evaluate the advantage of 4-D flow-based volumetric flow analysis compared to 2-D phase-contrast MRI and echo for peak velocity assessment in children and young adults. Two-dimensional phase-contrast MRI of the aortic root, main pulmonary artery (MPA), and right and left pulmonary arteries (RPA, LPA) and 4-D flow with volumetric coverage of the aorta and pulmonary arteries were performed in 50 patients (mean age: 13.1 ± 6.4 years). Four-dimensional flow analyses included calculation of net flow and regurgitant fraction with 4-D flow analysis planes similarly positioned to 2-D planes. In addition, 4-D flow volumetric assessment of aortic root/ascending aorta and MPA peak velocities was performed and compared to 2-D phase-contrast MRI and echo. Excellent correlation and agreement were found between 2-D phase-contrast MRI and 4-D flow for net flow (r = 0.97, P < 0.001) and excellent correlation with good agreement was found for regurgitant fraction (r = 0.88, P < 0.001) in all vessels. Two-dimensional phase-contrast MRI significantly underestimated aortic (P = 0.032) and MPA (P < 0.001) peak velocities compared to echo, while volumetric 4-D flow analysis resulted in higher (aortic: P = 0.001) or similar (MPA: P = 0.98) peak

  13. Two components of Na emission in sonoluminescence spectrum from surfactant aqueous solutions.

    Science.gov (United States)

    Hayashi, Yuichi; Choi, Pak-Kon

    2015-03-01

    Sonoluminescence from sodium dodecyl sulfate (SDS) aqueous solutions exhibits Na emission. The spectrum of Na emission was measured as a function of sonication time for a total of 30 min at an ultrasonic frequency of 148 kHz. The spectral line profiles changed with the sonication time, suggesting that the Na emission consists of two components: broadened lines, which are shifted from the original D lines, and unshifted narrow lines. The intensity of the unshifted narrow lines decreased at a greater rate than that of the broadened lines with increasing sonication time. This effect was enhanced at a higher acoustic power. The shifted broadened lines remained after sonication for 30 min. We propose that these quenching effects are caused by the accumulation of gases decomposed from SDS molecules inside bubbles. The CO₂ gas dependence of Na emission in NaCl aqueous solutions showed a similar change in the line profiles to that in SDS aqueous solutions, which supported this proposition. The unshifted narrow lines are easily affected by foreign gases. The results suggest that the two components originate from different environments around the emitting species, although both of them originate from the gas phase inside bubbles. The generation mechanisms of the two components are discussed. Copyright © 2014 Elsevier B.V. All rights reserved.

  14. Two-component fluid membranes near repulsive walls: Linearized hydrodynamics of equilibrium and nonequilibrium states.

    Science.gov (United States)

    Sankararaman, Sumithra; Menon, Gautam I; Sunil Kumar, P B

    2002-09-01

    We study the linearized hydrodynamics of a two-component fluid membrane near a repulsive wall, using a model that incorporates curvature-concentration coupling as well as hydrodynamic interactions. This model is a simplified version of a recently proposed one [J.-B. Manneville et al., Phys. Rev. E 64, 021908 (2001)] for nonequilibrium force centers embedded in fluid membranes, such as light-activated bacteriorhodopsin pumps incorporated in phospholipid egg phosphatidyl choline (EPC) bilayers. The pump-membrane system is modeled as an impermeable, two-component bilayer fluid membrane in the presence of an ambient solvent, in which one component, representing active pumps, is described in terms of force dipoles displaced with respect to the bilayer midpoint. We first discuss the case in which such pumps are rendered inactive, computing the mode structure in the bulk as well as the modification of hydrodynamic properties by the presence of a nearby wall. These results should apply, more generally, to equilibrium fluid membranes comprised of two components, in which the effects of curvature-concentration coupling are significant, above the threshold for phase separation. We then discuss the fluctuations and mode structure in the steady state of active two-component membranes near a repulsive wall. We find that proximity to the wall smoothens membrane height fluctuations in the stable regime, resulting in a logarithmic scaling of the roughness even for initially tensionless membranes. This explicitly nonequilibrium result is a consequence of the incorporation of curvature-concentration coupling in our hydrodynamic treatment. This result also indicates that earlier scaling arguments which obtained an increase in the roughness of active membranes near repulsive walls upon neglecting the role played by such couplings may need to be reevaluated.

  15. The two-component afterglow of Swift GRB 050802

    Science.gov (United States)

    Oates, S. R.; de Pasquale, M.; Page, M. J.; Blustin, A. J.; Zane, S.; McGowan, K.; Mason, K. O.; Poole, T. S.; Schady, P.; Roming, P. W. A.; Page, K. L.; Falcone, A.; Gehrels, N.

    2007-09-01

    This paper investigates GRB 050802, one of the best examples of a Swift gamma-ray burst afterglow that shows a break in the X-ray light curve, while the optical counterpart decays as a single power law. This burst has an optically bright afterglow of 16.5 mag, detected throughout the 170-650nm spectral range of the Ultraviolet and Optical Telescope (UVOT) onboard Swift. Observations began with the X-ray Telescope and UVOT telescopes 286s after the initial trigger and continued for 1.2 ×106s. The X-ray light curve consists of three power-law segments: a rise until 420s, followed by a slow decay with α =0.63 +/-0.03 until 5000s, after which, the light curve decays faster with a slope of α3 =1.59 +/-0.03. The optical light curve decays as a single power law with αO =0.82 +/-0.03 throughout the observation. The X-ray data on their own are consistent with the break at 5000s being due to the end of energy injection. Modelling the optical to X-ray spectral energy distribution, we find that the optical afterglow cannot be produced by the same component as the X-ray emission at late times, ruling out a single-component afterglow. We therefore considered two-component jet models and find that the X-ray and optical emission is best reproduced by a model in which both components are energy injected for the duration of the observed afterglow and the X-ray break at 5000s is due to a jet break in the narrow component. This bright, well-observed burst is likely a guide for interpreting the surprising finding of Swift that bursts seldom display achromatic jet breaks.

  16. Complexation in two-component chlortetracycline-melanin solutions

    Science.gov (United States)

    Lapina, V. A.; Pershukevich, P. P.; Dontsov, A. E.; Bel'Kov, M. V.

    2008-01-01

    The spectra and kinetics of fluorescence of two-component solutions of the chlortetracycline (CHTC)-DOPA-melanin (melanin or ME) system in water have been investigated. The data obtained have been compared to similar data for solutions of CHTC-melanosome from bull eye (MB), which contains natural melanin, in K-phosphate buffer at pH 7.4. The overall results indicate the occurrence of complexation between molecules of CHTC and ME as they are being excited. The studies of complexation in the solution of CHTC-MB in the buffer are complicated by the formation of a CHTC-buffer complex. The effect of optical radiation in the range 330-750 nm on the CHTC-ME complex shows selectivity: the greatest change in the spectrum occurs when the wavelength of the exciting radiation coincides with the long-wavelength band maximum of the fluorescence excitation spectrum of the CHTC-ME complex in aqueous solution. In this range, CHTC and especially ME show high photochemical stability. The nature of the radiation effect on the studied compounds in the hard UV range (λ < 330 nm) differs greatly from that in the range 330-750 nm. It is apparently accompanied by significant photochemical transmutations of all system components. By comparing the characteristics of the CHTC-ME systems with those of the related drug doxycycline (DC-ME), the conclusion has been made that the chlorine atom plays a vital role in formation of the short-wavelength band in the fluorescence spectrum of the CHTC-ME complex.

  17. Two component systems: physiological effect of a third component.

    Directory of Open Access Journals (Sweden)

    Baldiri Salvado

    Full Text Available Signal transduction systems mediate the response and adaptation of organisms to environmental changes. In prokaryotes, this signal transduction is often done through Two Component Systems (TCS. These TCS are phosphotransfer protein cascades, and in their prototypical form they are composed by a kinase that senses the environmental signals (SK and by a response regulator (RR that regulates the cellular response. This basic motif can be modified by the addition of a third protein that interacts either with the SK or the RR in a way that could change the dynamic response of the TCS module. In this work we aim at understanding the effect of such an additional protein (which we call "third component" on the functional properties of a prototypical TCS. To do so we build mathematical models of TCS with alternative designs for their interaction with that third component. These mathematical models are analyzed in order to identify the differences in dynamic behavior inherent to each design, with respect to functionally relevant properties such as sensitivity to changes in either the parameter values or the molecular concentrations, temporal responsiveness, possibility of multiple steady states, or stochastic fluctuations in the system. The differences are then correlated to the physiological requirements that impinge on the functioning of the TCS. This analysis sheds light on both, the dynamic behavior of synthetically designed TCS, and the conditions under which natural selection might favor each of the designs. We find that a third component that modulates SK activity increases the parameter space where a bistable response of the TCS module to signals is possible, if SK is monofunctional, but decreases it when the SK is bifunctional. The presence of a third component that modulates RR activity decreases the parameter space where a bistable response of the TCS module to signals is possible.

  18. Non-Contact Sensor for Long-Term Continuous Vital Signs Monitoring: A Review on Intelligent Phased-Array Doppler Sensor Design

    Science.gov (United States)

    Hall, Travis; Nguyen, Tam Q.; Mayeda, Jill C.; Lie, Paul E.; Lopez, Jerry; Banister, Ron E.

    2017-01-01

    It has been the dream of many scientists and engineers to realize a non-contact remote sensing system that can perform continuous, accurate and long-term monitoring of human vital signs as we have seen in many Sci-Fi movies. Having an intelligible sensor system that can measure and record key vital signs (such as heart rates and respiration rates) remotely and continuously without touching the patients, for example, can be an invaluable tool for physicians who need to make rapid life-and-death decisions. Such a sensor system can also effectively help physicians and patients making better informed decisions when patients’ long-term vital signs data is available. Therefore, there has been a lot of research activities on developing a non-contact sensor system that can monitor a patient’s vital signs and quickly transmit the information to healthcare professionals. Doppler-based radio-frequency (RF) non-contact vital signs (NCVS) monitoring system are particularly attractive for long term vital signs monitoring because there are no wires, electrodes, wearable devices, nor any contact-based sensors involved so the subjects may not be even aware of the ubiquitous monitoring. In this paper, we will provide a brief review on some latest development on NCVS sensors and compare them against a few novel and intelligent phased-array Doppler-based RF NCVS biosensors we have built in our labs. Some of our NCVS sensor tests were performed within a clutter-free anechoic chamber to mitigate the environmental clutters, while most tests were conducted within the typical Herman-Miller type office cubicle setting to mimic a more practical monitoring environment. Additionally, we will show the measurement data to demonstrate the feasibility of long-term NCVS monitoring. The measured data strongly suggests that our latest phased array NCVS system should be able to perform long-term vital signs monitoring intelligently and robustly, especially for situations where the subject is

  19. Non-Contact Sensor for Long-Term Continuous Vital Signs Monitoring: A Review on Intelligent Phased-Array Doppler Sensor Design

    Directory of Open Access Journals (Sweden)

    Travis Hall

    2017-11-01

    Full Text Available It has been the dream of many scientists and engineers to realize a non-contact remote sensing system that can perform continuous, accurate and long-term monitoring of human vital signs as we have seen in many Sci-Fi movies. Having an intelligible sensor system that can measure and record key vital signs (such as heart rates and respiration rates remotely and continuously without touching the patients, for example, can be an invaluable tool for physicians who need to make rapid life-and-death decisions. Such a sensor system can also effectively help physicians and patients making better informed decisions when patients’ long-term vital signs data is available. Therefore, there has been a lot of research activities on developing a non-contact sensor system that can monitor a patient’s vital signs and quickly transmit the information to healthcare professionals. Doppler-based radio-frequency (RF non-contact vital signs (NCVS monitoring system are particularly attractive for long term vital signs monitoring because there are no wires, electrodes, wearable devices, nor any contact-based sensors involved so the subjects may not be even aware of the ubiquitous monitoring. In this paper, we will provide a brief review on some latest development on NCVS sensors and compare them against a few novel and intelligent phased-array Doppler-based RF NCVS biosensors we have built in our labs. Some of our NCVS sensor tests were performed within a clutter-free anechoic chamber to mitigate the environmental clutters, while most tests were conducted within the typical Herman-Miller type office cubicle setting to mimic a more practical monitoring environment. Additionally, we will show the measurement data to demonstrate the feasibility of long-term NCVS monitoring. The measured data strongly suggests that our latest phased array NCVS system should be able to perform long-term vital signs monitoring intelligently and robustly, especially for situations where the

  20. Local measurements in two-phase flow using a double-sensor conductivity probes and laser doppler anemometry in a vertical pipe

    International Nuclear Information System (INIS)

    Chiva, S.; Julia, E.; Hernandez, L.; Mendez, S.; Munoz-Cobo, J.L.

    2007-01-01

    An upward isothermal co-current air-water flow in a vertical pipe (50.2 mm inner diameter) has been experimental investigated. Local measurements of void fraction, interfacial area concentration (IAC), and interfacial velocity and Sauter mean diameter were measured using a double sensor conductivity probe. Liquid velocity and turbulence intensity were measured using laser Doppler anemometry. Different air-water flow configurations was investigated for a liquid flow rate ranged from 0.29 m/s to 2 m/s and a void fraction up to 15%. For each two-phase flow configuration 15 radial position and three axial positions was measured by the conductivity probe methodology, and several radial profiles was measured with LDA at different axial positions. Two theoretical calibration factors have been defined to relate the mean measurable parameter to the interfacial area concentrations obtained and the measured bubbles, including the missed bubbles. Those factors include the effects of bubble motions, and probe spacing. These calibration factors were obtained through new analytical and numerical method, using a Monte Carlo approach. (author)

  1. Viscous Growth in Spinodal Decomposition of the Two-component Lennard-Jones Model in Two Dimensions

    DEFF Research Database (Denmark)

    Laradji, M.; Toxvaerd, S.; Mouritsen, Ole G.

    1997-01-01

    The dynamics of phase separation of a two-component Lennard-Jones model in three dimensions is investigated by means of large scale molecular dynamics simulation. A systematic study over a wide range of quench temperatures within the coexistence region shows that the binary system reaches...

  2. Vascularization of liver tumors - preliminary results with Coded Harmonic Angio (CHA), phase inversion imaging, 3D power Doppler and contrast medium-enhanced B-flow with second generation contrast agent (Optison).

    Science.gov (United States)

    Jung, E M; Kubale, R; Jungius, K-P; Jung, W; Lenhart, M; Clevert, D-A

    2006-01-01

    To investigate the dynamic value of contrast medium-enhanced ultrasonography with Optison for appraisal of the vascularization of hepatic tumors using harmonic imaging, 3D-/power Doppler and B-flow. 60 patients with a mean age of 56 years (range 35-76 years) with 93 liver tumors, including histopathologically proven hepatocellular carcinoma (HCC) [15 cases with 20 lesions], liver metastases of colorectal tumors [17 cases with 33 lesions], metastases of breast cancer [10 cases with 21 lesions] and hemangiomas [10 cases with 19 lesions] were prospectively investigated by means of multislice CT as well as native and contrast medium-enhanced ultrasound using a multifrequency transducer (2.5-4 MHz, Logig 9, GE). B scan was performed with additional color and power Doppler, followed by a bolus injection of 0.5 ml Optison. Tumor vascularization was evaluated with coded harmonic angio (CHA), pulse inversion imaging with power Doppler, 3D power Doppler and in the late phase (>5 min) with B-flow. In 15 cases with HCC, i.a. DSA was performed in addition. The results were also correlated with MRT and histological findings. Compared to spiral-CT/MRT, only 72/93 (77%) of the lesions could be detected in the B scan, 75/93 (81%) with CHA and 93/93 (100%) in the pulse inversion mode. Tumor vascularization was detectable in 43/93 (46%) of lesions with native power Doppler, in 75/93 (81%) of lesions after administering contrast medium in the CHA mode, in 81/93 (87%) of lesions in the pulse inversion mode with power Doppler and in 77/93 (83%) of lesions with contrast-enhanced B-flow. Early arterial and capillary perfusion was best detected with CHA, particularly in 20/20 (100%) of the HCC lesions, allowing a 3D reconstruction. 3D power Doppler was especially useful in investigating the tumor margins. Up to 20 min after contrast medium injection, B-flow was capable of detecting increased metastatic tumor vascularization in 42/54 (78%) of cases and intratumoral perfusion in 17/20 (85

  3. Non-invasive classification of gas–liquid two-phase horizontal flow regimes using an ultrasonic Doppler sensor and a neural network

    International Nuclear Information System (INIS)

    Abbagoni, Baba Musa; Yeung, Hoi

    2016-01-01

    The identification of flow pattern is a key issue in multiphase flow which is encountered in the petrochemical industry. It is difficult to identify the gas–liquid flow regimes objectively with the gas–liquid two-phase flow. This paper presents the feasibility of a clamp-on instrument for an objective flow regime classification of two-phase flow using an ultrasonic Doppler sensor and an artificial neural network, which records and processes the ultrasonic signals reflected from the two-phase flow. Experimental data is obtained on a horizontal test rig with a total pipe length of 21 m and 5.08 cm internal diameter carrying air-water two-phase flow under slug, elongated bubble, stratified-wavy and, stratified flow regimes. Multilayer perceptron neural networks (MLPNNs) are used to develop the classification model. The classifier requires features as an input which is representative of the signals. Ultrasound signal features are extracted by applying both power spectral density (PSD) and discrete wavelet transform (DWT) methods to the flow signals. A classification scheme of ‘1-of-C coding method for classification’ was adopted to classify features extracted into one of four flow regime categories. To improve the performance of the flow regime classifier network, a second level neural network was incorporated by using the output of a first level networks feature as an input feature. The addition of the two network models provided a combined neural network model which has achieved a higher accuracy than single neural network models. Classification accuracies are evaluated in the form of both the PSD and DWT features. The success rates of the two models are: (1) using PSD features, the classifier missed 3 datasets out of 24 test datasets of the classification and scored 87.5% accuracy; (2) with the DWT features, the network misclassified only one data point and it was able to classify the flow patterns up to 95.8% accuracy. This approach has demonstrated the

  4. Non-invasive classification of gas-liquid two-phase horizontal flow regimes using an ultrasonic Doppler sensor and a neural network

    Science.gov (United States)

    Musa Abbagoni, Baba; Yeung, Hoi

    2016-08-01

    The identification of flow pattern is a key issue in multiphase flow which is encountered in the petrochemical industry. It is difficult to identify the gas-liquid flow regimes objectively with the gas-liquid two-phase flow. This paper presents the feasibility of a clamp-on instrument for an objective flow regime classification of two-phase flow using an ultrasonic Doppler sensor and an artificial neural network, which records and processes the ultrasonic signals reflected from the two-phase flow. Experimental data is obtained on a horizontal test rig with a total pipe length of 21 m and 5.08 cm internal diameter carrying air-water two-phase flow under slug, elongated bubble, stratified-wavy and, stratified flow regimes. Multilayer perceptron neural networks (MLPNNs) are used to develop the classification model. The classifier requires features as an input which is representative of the signals. Ultrasound signal features are extracted by applying both power spectral density (PSD) and discrete wavelet transform (DWT) methods to the flow signals. A classification scheme of ‘1-of-C coding method for classification’ was adopted to classify features extracted into one of four flow regime categories. To improve the performance of the flow regime classifier network, a second level neural network was incorporated by using the output of a first level networks feature as an input feature. The addition of the two network models provided a combined neural network model which has achieved a higher accuracy than single neural network models. Classification accuracies are evaluated in the form of both the PSD and DWT features. The success rates of the two models are: (1) using PSD features, the classifier missed 3 datasets out of 24 test datasets of the classification and scored 87.5% accuracy; (2) with the DWT features, the network misclassified only one data point and it was able to classify the flow patterns up to 95.8% accuracy. This approach has demonstrated the

  5. Two-component Superfluid Hydrodynamics of Neutron Star Cores

    Energy Technology Data Exchange (ETDEWEB)

    Kobyakov, D. N. [Institute of Applied Physics of the Russian Academy of Sciences, 603950 Nizhny Novgorod (Russian Federation); Pethick, C. J., E-mail: dmitry.kobyakov@appl.sci-nnov.ru, E-mail: pethick@nbi.dk [The Niels Bohr International Academy, The Niels Bohr Institute, University of Copenhagen, Blegdamsvej 17, DK-2100 Copenhagen Ø (Denmark)

    2017-02-20

    We consider the hydrodynamics of the outer core of a neutron star under conditions when both neutrons and protons are superfluid. Starting from the equation of motion for the phases of the wave functions of the condensates of neutron pairs and proton pairs, we derive the generalization of the Euler equation for a one-component fluid. These equations are supplemented by the conditions for conservation of neutron number and proton number. Of particular interest is the effect of entrainment, the fact that the current of one nucleon species depends on the momenta per nucleon of both condensates. We find that the nonlinear terms in the Euler-like equation contain contributions that have not always been taken into account in previous applications of superfluid hydrodynamics. We apply the formalism to determine the frequency of oscillations about a state with stationary condensates and states with a spatially uniform counterflow of neutrons and protons. The velocities of the coupled sound-like modes of neutrons and protons are calculated from properties of uniform neutron star matter evaluated on the basis of chiral effective field theory. We also derive the condition for the two-stream instability to occur.

  6. Superfluid drag in the two-component Bose-Hubbard model

    Science.gov (United States)

    Sellin, Karl; Babaev, Egor

    2018-03-01

    In multicomponent superfluids and superconductors, co- and counterflows of components have, in general, different properties. A. F. Andreev and E. P. Bashkin [Sov. Phys. JETP 42, 164 (1975)] discussed, in the context of He3/He4 superfluid mixtures, that interparticle interactions produce a dissipationless drag. The drag can be understood as a superflow of one component induced by phase gradients of the other component. Importantly, the drag can be both positive (entrainment) and negative (counterflow). The effect is known to have crucial importance for many properties of diverse physical systems ranging from the dynamics of neutron stars and rotational responses of Bose mixtures of ultracold atoms to magnetic responses of multicomponent superconductors. Although substantial literature exists that includes the drag interaction phenomenologically, only a few regimes are covered by quantitative studies of the microscopic origin of the drag and its dependence on microscopic parameters. Here we study the microscopic origin and strength of the drag interaction in a quantum system of two-component bosons on a lattice with short-range interaction. By performing quantum Monte Carlo simulations of a two-component Bose-Hubbard model we obtain dependencies of the drag strength on the boson-boson interactions and properties of the optical lattice. Of particular interest are the strongly correlated regimes where the ratio of coflow and counterflow superfluid stiffnesses can diverge, corresponding to the case of saturated drag.

  7. A Ground-Based Doppler Radar and Micropulse Lidar Forward Simulator for GCM Evaluation of Arctic Mixed-Phase Clouds: Moving Forward Towards an Apples-to-apples Comparison of Hydrometeor Phase

    Science.gov (United States)

    Lamer, K.; Fridlind, A. M.; Ackerman, A. S.; Kollias, P.; Clothiaux, E. E.

    2017-12-01

    An important aspect of evaluating Artic cloud representation in a general circulation model (GCM) consists of using observational benchmarks which are as equivalent as possible to model output in order to avoid methodological bias and focus on correctly diagnosing model dynamical and microphysical misrepresentations. However, current cloud observing systems are known to suffer from biases such as limited sensitivity, and stronger response to large or small hydrometeors. Fortunately, while these observational biases cannot be corrected, they are often well understood and can be reproduced in forward simulations. Here a ground-based millimeter wavelength Doppler radar and micropulse lidar forward simulator able to interface with output from the Goddard Institute for Space Studies (GISS) ModelE GCM is presented. ModelE stratiform hydrometeor fraction, mixing ratio, mass-weighted fall speed and effective radius are forward simulated to vertically-resolved profiles of radar reflectivity, Doppler velocity and spectrum width as well as lidar backscatter and depolarization ratio. These forward simulated fields are then compared to Atmospheric Radiation Measurement (ARM) North Slope of Alaska (NSA) ground-based observations to assess cloud vertical structure (CVS). Model evalution of Arctic mixed-phase cloud would also benefit from hydrometeor phase evaluation. While phase retrieval from synergetic observations often generates large uncertainties, the same retrieval algorithm can be applied to observed and forward-simulated radar-lidar fields, thereby producing retrieved hydrometeor properties with potentially the same uncertainties. Comparing hydrometeor properties retrieved in exactly the same way aims to produce the best apples-to-apples comparisons between GCM ouputs and observations. The use of a comprenhensive ground-based forward simulator coupled with a hydrometeor classification retrieval algorithm provides a new perspective for GCM evaluation of Arctic mixed-phase

  8. Adaptive Spectral Doppler Estimation

    DEFF Research Database (Denmark)

    Gran, Fredrik; Jakobsson, Andreas; Jensen, Jørgen Arendt

    2009-01-01

    . The methods can also provide better quality of the estimated power spectral density (PSD) of the blood signal. Adaptive spectral estimation techniques are known to pro- vide good spectral resolution and contrast even when the ob- servation window is very short. The 2 adaptive techniques are tested......In this paper, 2 adaptive spectral estimation techniques are analyzed for spectral Doppler ultrasound. The purpose is to minimize the observation window needed to estimate the spectrogram to provide a better temporal resolution and gain more flexibility when designing the data acquisition sequence...... and compared with the averaged periodogram (Welch’s method). The blood power spectral capon (BPC) method is based on a standard minimum variance technique adapted to account for both averaging over slow-time and depth. The blood amplitude and phase estimation technique (BAPES) is based on finding a set...

  9. Sub-Doppler spectroscopy

    International Nuclear Information System (INIS)

    Hansch, T.W.

    1983-01-01

    This chapter examines Doppler-free saturation spectroscopy, tunable cw sources, and Doppler-free two-photon spectroscopy. Discusses saturation spectroscopy; continuous wave saturation spectroscopy in the ultraviolet; and two-photon spectroscopy of atomic hydrogen 1S-2S. Focuses on Doppler-free laser spectroscopy of gaseous samples. Explains that in saturation spectroscopy, a monochromatic laser beam ''labels'' a group of atoms within a narrow range of axial velocities through excitation or optical pumping, and a Doppler-free spectrum of these selected atoms is observed with a second, counterpropagating beam. Notes that in two-photon spectroscopy it is possible to record Doppler-free spectra without any need for velocity selection by excitation with two counterpropagating laser beams whose first order Doppler shifts cancel

  10. Doppler flowmetry in preeclampsia.

    Science.gov (United States)

    Zahumensky, J

    2009-01-01

    The purpose of this study was to summarize the new published data on the Doppler flowmetry in preeclampsia. We summarize the new published data on the Doppler flowmetry in uteroplacental, fetoplacental and fetal circulation in preeclampsia. The present review summarized the results of clinical research on the Doppler flowmetry in the screening of risk of preclampsia, in the diagnosis of preclampsia and in the fetal risk in preclampsia (Ref. 19). Full Text (Free, PDF) www.bmj.sk.

  11. ACOUSTIC WAVES EMISSION IN THE TWO-COMPONENT HEREDITARY-ELASTIC MEDIUM

    Directory of Open Access Journals (Sweden)

    V. S. Polenov

    2014-01-01

    Full Text Available Summary. On the dynamics of two-component media a number of papers, which address the elastic waves in a homogeneous, unbounded fluid-saturated porous medium. In other studies address issues of dissipative processes in harmonic deformation hereditary elastic medium. In the article the dissipative processes of the viscoelastic porous medium, which hereditary properties are described by the core relaxation fractional exponential function U.N. Rabotnova integro-differential Boltzmann-Volterr ratio, harmonic deformation by the straining saturated incompressible liquid are investigated. Speed of wave propagation, absorption coefficient, mechanical loss tangent, logarithmic decrement, depending on fractional parameter γ, determining formulas received. The frequency logarithm and temperature graph dependences with the goal fractional parameter are constructed. Shows the dependences velocity and attenuation coefficient of the tangent of the phase angle of the logarithm of the temperature, and the dependence of the attenuation coefficient of the logarithm of the frequency. Dependencies the speed and the tangent of the phase angle of the frequency identical function of the logarithm of temperature.

  12. Spray Evaporation in Turbulent Flow: Numerical Calculations and Detailed Experiments by Phase-Doppler Anemometry Évaporation de brouillard en flux turbulent : calculs numériques et expériences détaillées par anémometrie de phase-Doppler

    Directory of Open Access Journals (Sweden)

    Sommerfeld M.

    2006-11-01

    Full Text Available The present paper concerns experiments and numerical calculations of an isopropyl-alcohol spray evaporating in a co-flowing turbulent heated air flow. The measurements provided detailed inlet and boundary conditions for the numerical calculations and allowed the validation of the numerical method and models. Phase-Doppler anemometry was used in order to obtain the spatial change of the droplet size distribution and the correlation between droplet size and velocity throughout the flow field. Additionally, a reliable method based on the detection of the signal amplitudes was applied to determine the droplet mass flux. By integration of the droplet mass flux profiles, the global evaporation rates could be determined for different flow conditions. Numerical calculations of the evaporating spray were performed by the Eulerian / Lagrangian approach. The modelling of droplet evaporation is briefly reviewed prior to the description of the applied numerical models and methods. Calculations for a single phase flow showed good agreement with the experiments. Also for all of the droplet phase properties reasonable agreement with the experiments could be achieved and the global evaporation rates agreed well with the measurements. Cet article expose en détail les expériences et les calculs concernant l'évaporation d'isopropanol pulvérisé dans un flux d'air chaud turbulent. Les mesures ont fourni le détail des conditions initiales et des conditions limites pour les calculs numériques ; elles ont également permis de valider la méthode et le modèle. L'anémométrie de phase-Doppler a permis de définir la modification spatiale de la distribution des dimensions de gouttelettes ainsi que la corrélation entre dimension et vitesse des gouttelettes, dans l'ensemble du champ d'écoulement. De plus, une méthode fiable fondée sur la détection des amplitudes de signal a été appliquée afin de déterminer le débit massique des gouttelettes. L

  13. Doppler ultrasound exam of an arm or leg

    Science.gov (United States)

    Peripheral vascular disease - Doppler; PVD - Doppler; PAD - Doppler; Blockage of leg arteries - Doppler; Intermittent claudication - Doppler; Arterial insufficiency of the legs - Doppler; Leg pain and ...

  14. Differential doppler heterodyning technique

    DEFF Research Database (Denmark)

    Lading, Lars

    1971-01-01

    Measuring velocity without disturbing the moving object is possible by use of the laser doppler heterodyning technique. Theoretical considerations on the doppler shift show that the antenna property of the photodetector can solve an apparent conflict between two different ways of calculating...

  15. Doppler ultrasound monitoring technology.

    Science.gov (United States)

    Docker, M F

    1993-03-01

    Developments in the signal processing of Doppler ultrasound used for the detection of fetal heart rate (FHR) have improved the operation of cardiotocographs. These developments are reviewed and the advantages and disadvantages of the various Doppler and signal processing methods are compared.

  16. The Cognitive Doppler.

    Science.gov (United States)

    Kozoil, Micah E.

    1989-01-01

    Discusses the learning needs of students in the concrete operational stage in mathematics. Identifies the phenomenon of reduced cognitive performance in an out-of-class environment as the "Cognitive Doppler." Suggests methods of reducing the pronounced effects of the Cognitive Doppler by capitalizing on the students' ability to memorize…

  17. Fluorescence lifetime selectivity in excitation-emission matrices for qualitative analysis of a two-component system

    International Nuclear Information System (INIS)

    Millican, D.W.; McGown, L.B.

    1989-01-01

    Steady-state fluorescence excitation-emission matrices (EEMs), and phase-resolved EEMs (PREEMs) collected at modulation frequencies of 6, 18, and 30 MHz, were used for qualitative analysis of mixtures of benzo[k]fluoranthene (τ = 8 ns) and benzo[b]fluoranthene (τ = 29 ns) in ethanol. The EEMs of the individual components were extracted from mixture EEMs by means of wavelength component vector-gram (WCV) analysis. Phase resolution was found to be superior to steady-state measurements for extraction of the component spectra, for mixtures in which the intensity contributions from the two components are unequal

  18. Ultrasonic colour Doppler imaging

    DEFF Research Database (Denmark)

    Evans, David H.; Jensen, Jørgen Arendt; Nielsen, Michael Bachmann

    2011-01-01

    Ultrasonic colour Doppler is an imaging technique that combines anatomical information derived using ultrasonic pulse-echo techniques with velocity information derived using ultrasonic Doppler techniques to generate colour-coded maps of tissue velocity superimposed on grey-scale images of tissue...... anatomy. The most common use of the technique is to image the movement of blood through the heart, arteries and veins, but it may also be used to image the motion of solid tissues such as the heart walls. Colour Doppler imaging is now provided on almost all commercial ultrasound machines, and has been...... vectors. This review briefly introduces the principles behind colour Doppler imaging and describes some clinical applications. It then describes the basic components of conventional colour Doppler systems and the methods used to derive velocity information from the ultrasound signal. Next, a number of new...

  19. Two-Component Signal Transduction Systems That Regulate the Temporal and Spatial Expression of Myxococcus xanthus Sporulation Genes.

    Science.gov (United States)

    Sarwar, Zaara; Garza, Anthony G

    2016-02-01

    When starved for nutrients, Myxococcus xanthus produces a biofilm that contains a mat of rod-shaped cells, known as peripheral rods, and aerial structures called fruiting bodies, which house thousands of dormant and stress-resistant spherical spores. Because rod-shaped cells differentiate into spherical, stress-resistant spores and spore differentiation occurs only in nascent fruiting bodies, many genes and multiple levels of regulation are required. Over the past 2 decades, many regulators of the temporal and spatial expression of M. xanthus sporulation genes have been uncovered. Of these sporulation gene regulators, two-component signal transduction circuits, which typically contain a histidine kinase sensor protein and a transcriptional regulator known as response regulator, are among the best characterized. In this review, we discuss prototypical two-component systems (Nla6S/Nla6 and Nla28S/Nla28) that regulate an early, preaggregation phase of sporulation gene expression during fruiting body development. We also discuss orphan response regulators (ActB and FruA) that regulate a later phase of sporulation gene expression, which begins during the aggregation stage of fruiting body development. In addition, we summarize the research on a complex two-component system (Esp) that is important for the spatial regulation of sporulation. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  20. A Class of Two-Component Adler—Bobenko—Suris Lattice Equations

    International Nuclear Information System (INIS)

    Fu Wei; Zhang Da-Jun; Zhou Ru-Guang

    2014-01-01

    We study a class of two-component forms of the famous list of the Adler—Bobenko—Suris lattice equations. The obtained two-component lattice equations are still consistent around the cube and they admit solutions with ‘jumping properties’ between two levels. (general)

  1. Two-component regulators involved in the global control of virulence in Erwinia carotovora subsp. carotovora.

    Science.gov (United States)

    Eriksson, A R; Andersson, R A; Pirhonen, M; Palva, E T

    1998-08-01

    Production of extracellular, plant cell wall degrading enzymes, the main virulence determinants of the plant pathogen Erwinia carotovora subsp. carotovora, is coordinately controlled by a complex regulatory network. Insertion mutants in the exp (extracellular enzyme production) loci exhibit pleiotropic defects in virulence and the growth-phase-dependent transcriptional activation of genes encoding extracellular enzymes. Two new exp mutations, designated expA and expS, were characterized. Introduction of the corresponding wild-type alleles to the mutants complemented both the lack of virulence and the impaired production of plant cell wall degrading enzymes. The expA gene was shown to encode a 24-kDa polypeptide that is structurally and functionally related to the uvrY gene product of Escherichia coli and the GacA response regulator of Pseudomonas fluorescens. Functional similarity of expA and uvrY was demonstrated by genetic complementation. The expA gene is organized in an operon together with a uvrC-like gene, identical to the organization of uvrY and uvrC in E. coli. The unlinked expS gene encodes a putative sensor kinase that shows 92% identity to the recently described rpfA gene product from another E. carotovora subsp. carotovora strain. Our data suggest that ExpS and ExpA are members of two-component sensor kinase and response regulator families, respectively. These two proteins might interact in controlling virulence gene expression in E. carotovora subsp. carotovora.

  2. Doppler radar flowmeter

    Science.gov (United States)

    Petlevich, Walter J.; Sverdrup, Edward F.

    1978-01-01

    A Doppler radar flowmeter comprises a transceiver which produces an audio frequency output related to the Doppler shift in frequency between radio waves backscattered from particulate matter carried in a fluid and the radiated radio waves. A variable gain amplifier and low pass filter are provided for amplifying and filtering the transceiver output. A frequency counter having a variable triggering level is also provided to determine the magnitude of the Doppler shift. A calibration method is disclosed wherein the amplifier gain and frequency counter trigger level are adjusted to achieve plateaus in the output of the frequency counter and thereby allow calibration without the necessity of being able to visually observe the flow.

  3. Ultrasonic colour Doppler imaging

    DEFF Research Database (Denmark)

    Evans, David H; Jensen, Jørgen Arendt; Nielsen, Michael Bachmann

    2011-01-01

    Ultrasonic colour Doppler is an imaging technique that combines anatomical information derived using ultrasonic pulse-echo techniques with velocity information derived using ultrasonic Doppler techniques to generate colour-coded maps of tissue velocity superimposed on grey-scale images of tissue...... anatomy. The most common use of the technique is to image the movement of blood through the heart, arteries and veins, but it may also be used to image the motion of solid tissues such as the heart walls. Colour Doppler imaging is now provided on almost all commercial ultrasound machines, and has been...

  4. Methods of producing epoxides from alkenes using a two-component catalyst system

    Science.gov (United States)

    Kung, Mayfair C.; Kung, Harold H.; Jiang, Jian

    2013-07-09

    Methods for the epoxidation of alkenes are provided. The methods include the steps of exposing the alkene to a two-component catalyst system in an aqueous solution in the presence of carbon monoxide and molecular oxygen under conditions in which the alkene is epoxidized. The two-component catalyst system comprises a first catalyst that generates peroxides or peroxy intermediates during oxidation of CO with molecular oxygen and a second catalyst that catalyzes the epoxidation of the alkene using the peroxides or peroxy intermediates. A catalyst system composed of particles of suspended gold and titanium silicalite is one example of a suitable two-component catalyst system.

  5. Weak nonlinear matter waves in a trapped two-component Bose-Einstein condensates

    International Nuclear Information System (INIS)

    Yong Wenmei; Xue Jukui

    2008-01-01

    The dynamics of the weak nonlinear matter solitary waves in two-component Bose-Einstein condensates (BEC) with cigar-shaped external potential are investigated analytically by a perturbation method. In the small amplitude limit, the two-components can be decoupled and the dynamics of solitary waves are governed by a variable-coefficient Korteweg-de Vries (KdV) equation. The reduction to the KdV equation may be useful to understand the dynamics of nonlinear matter waves in two-component BEC. The analytical expressions for the evolution of soliton, emitted radiation profiles and soliton oscillation frequency are also obtained

  6. Thermodynamics of two component gaseous and solid state plasmas at any degeneracy

    International Nuclear Information System (INIS)

    Kraeft, W.D.; Stolzmann, W.; Fromhold-Treu, I.; Rother, T.

    1988-10-01

    We give the results of thermodynamical calculations for two component plasmas which are of interest for dense hydrogen, noble gas and alkali plasmas and for electron hole plasmas in optically excited semiconductors as well. 25 refs, 4 figs

  7. Stability equation and two-component Eigenmode for domain walls in scalar potential model

    International Nuclear Information System (INIS)

    Dias, G.S.; Graca, E.L.; Rodrigues, R. de Lima

    2002-08-01

    Supersymmetric quantum mechanics involving a two-component representation and two-component eigenfunctions is applied to obtain the stability equation associated to a potential model formulated in terms of two coupled real scalar fields. We investigate the question of stability by introducing an operator technique for the Bogomol'nyi-Prasad-Sommerfield (BPS) and non-BPS states on two domain walls in a scalar potential model with minimal N 1-supersymmetry. (author)

  8. Competitive Adsorption of a Two-Component Gas on a Deformable Adsorbent

    OpenAIRE

    Usenko, A. S.

    2013-01-01

    We investigate the competitive adsorption of a two-component gas on the surface of an adsorbent whose adsorption properties vary in adsorption due to the adsorbent deformation. The essential difference of adsorption isotherms for a deformable adsorbent both from the classical Langmuir adsorption isotherms of a two-component gas and from the adsorption isotherms of a one-component gas taking into account variations in adsorption properties of the adsorbent in adsorption is obtained. We establi...

  9. Chloroplast two-component systems: evolution of the link between photosynthesis and gene expression.

    Science.gov (United States)

    Puthiyaveetil, Sujith; Allen, John F

    2009-06-22

    Two-component signal transduction, consisting of sensor kinases and response regulators, is the predominant signalling mechanism in bacteria. This signalling system originated in prokaryotes and has spread throughout the eukaryotic domain of life through endosymbiotic, lateral gene transfer from the bacterial ancestors and early evolutionary precursors of eukaryotic, cytoplasmic, bioenergetic organelles-chloroplasts and mitochondria. Until recently, it was thought that two-component systems inherited from an ancestral cyanobacterial symbiont are no longer present in chloroplasts. Recent research now shows that two-component systems have survived in chloroplasts as products of both chloroplast and nuclear genes. Comparative genomic analysis of photosynthetic eukaryotes shows a lineage-specific distribution of chloroplast two-component systems. The components and the systems they comprise have homologues in extant cyanobacterial lineages, indicating their ancient cyanobacterial origin. Sequence and functional characteristics of chloroplast two-component systems point to their fundamental role in linking photosynthesis with gene expression. We propose that two-component systems provide a coupling between photosynthesis and gene expression that serves to retain genes in chloroplasts, thus providing the basis of cytoplasmic, non-Mendelian inheritance of plastid-associated characters. We discuss the role of this coupling in the chronobiology of cells and in the dialogue between nuclear and cytoplasmic genetic systems.

  10. Comparative Analysis of Wolbachia Genomes Reveals Streamlining and Divergence of Minimalist Two-Component Systems

    Science.gov (United States)

    Christensen, Steen; Serbus, Laura Renee

    2015-01-01

    Two-component regulatory systems are commonly used by bacteria to coordinate intracellular responses with environmental cues. These systems are composed of functional protein pairs consisting of a sensor histidine kinase and cognate response regulator. In contrast to the well-studied Caulobacter crescentus system, which carries dozens of these pairs, the streamlined bacterial endosymbiont Wolbachia pipientis encodes only two pairs: CckA/CtrA and PleC/PleD. Here, we used bioinformatic tools to compare characterized two-component system relays from C. crescentus, the related Anaplasmataceae species Anaplasma phagocytophilum and Ehrlichia chaffeensis, and 12 sequenced Wolbachia strains. We found the core protein pairs and a subset of interacting partners to be highly conserved within Wolbachia and these other Anaplasmataceae. Genes involved in two-component signaling were positioned differently within the various Wolbachia genomes, whereas the local context of each gene was conserved. Unlike Anaplasma and Ehrlichia, Wolbachia two-component genes were more consistently found clustered with metabolic genes. The domain architecture and key functional residues standard for two-component system proteins were well-conserved in Wolbachia, although residues that specify cognate pairing diverged substantially from other Anaplasmataceae. These findings indicate that Wolbachia two-component signaling pairs share considerable functional overlap with other α-proteobacterial systems, whereas their divergence suggests the potential for regulatory differences and cross-talk. PMID:25809075

  11. Quantum particle-number fluctuations in a two-component Bose gas in a double-well potential

    International Nuclear Information System (INIS)

    Zin, Pawel; Oles, Bartlomiej; Sacha, Krzysztof

    2011-01-01

    A two-component Bose gas in a double-well potential with repulsive interactions may undergo a phase separation transition if the interspecies interactions outweigh the intraspecies ones. We analyze the transition in the strong interaction limit within the two-mode approximation. Numbers of particles in each potential well are equal and constant. However, at the transition point, the ground state of the system reveals huge fluctuations of numbers of particles belonging to the different gas components; that is, the probability for observation of any mixture of particles in each potential well becomes uniform.

  12. Burst Format Design for Optimum Joint Estimation of Doppler-Shift and Doppler-Rate in Packet Satellite Communications

    Directory of Open Access Journals (Sweden)

    Luca Giugno

    2007-05-01

    Full Text Available This paper considers the problem of optimizing the burst format of packet transmission to perform enhanced-accuracy estimation of Doppler-shift and Doppler-rate of the carrier of the received signal, due to relative motion between the transmitter and the receiver. Two novel burst formats that minimize the Doppler-shift and the Doppler-rate Cramér-Rao bounds (CRBs for the joint estimation of carrier phase/Doppler-shift and of the Doppler-rate are derived, and a data-aided (DA estimation algorithm suitable for each optimal burst format is presented. Performance of the newly derived estimators is evaluated by analysis and by simulation, showing that such algorithms attain their relevant CRBs with very low complexity, so that they can be directly embedded into new-generation digital modems for satellite communications at low SNR.

  13. Steerable Doppler transducer probes

    International Nuclear Information System (INIS)

    Fidel, H.F.; Greenwood, D.L.

    1986-01-01

    An ultrasonic diagnostic probe is described which is capable of performing ultrasonic imaging and Doppler measurement consisting of: a hollow case having an acoustic window which passes ultrasonic energy and including chamber means for containing fluid located within the hollow case and adjacent to a portion of the acoustic window; imaging transducer means, located in the hollow case and outside the fluid chamber means, and oriented to direct ultrasonic energy through the acoustic window toward an area which is to be imaged; Doppler transducer means, located in the hollow case within the fluid chamber means, and movably oriented to direct Doppler signals through the acoustic window toward the imaged area; means located within the fluid chamber means and externally controlled for controllably moving the Doppler transducer means to select one of a plurality of axes in the imaged area along which the Doppler signals are to be directed; and means, located external to the fluid chamber means and responsive to the means for moving, for providing an indication signal for identifying the selected axis

  14. Transcriptome analysis of all two-component regulatory system mutants of Escherichia coli K-12.

    Science.gov (United States)

    Oshima, Taku; Aiba, Hirofumi; Masuda, Yasushi; Kanaya, Shigehiko; Sugiura, Masahito; Wanner, Barry L; Mori, Hirotada; Mizuno, Takeshi

    2002-10-01

    We have systematically examined the mRNA profiles of 36 two-component deletion mutants, which include all two-component regulatory systems of Escherichia coli, under a single growth condition. DNA microarray results revealed that the mutants belong to one of three groups based on their gene expression profiles in Luria-Bertani broth under aerobic conditions: (i) those with no or little change; (ii) those with significant changes; and (iii) those with drastic changes. Under these conditions, the anaeroresponsive ArcB/ArcA system, the osmoresponsive EnvZ/OmpR system and the response regulator UvrY showed the most drastic changes. Cellular functions such as flagellar synthesis and expression of the RpoS regulon were affected by multiple two-component systems. A high correlation coefficient of expression profile was found between several two-component mutants. Together, these results support the view that a network of functional interactions, such as cross-regulation, exists between different two-component systems. The compiled data are avail-able at our website (http://ecoli.aist-nara.ac.jp/xp_analysis/ 2_components).

  15. Nonlinear low frequency electrostatic structures in a magnetized two-component auroral plasma

    Energy Technology Data Exchange (ETDEWEB)

    Rufai, O. R., E-mail: rajirufai@gmail.com [University of the Western Cape, Bellville 7535, Cape-Town (South Africa); Scientific Computing, Memorial University of Newfoundland, St John' s, Newfoundland and Labrador A1C 5S7 (Canada); Bharuthram, R., E-mail: rbharuthram@uwc.ac.za [University of the Western Cape, Bellville 7535, Cape-Town (South Africa); Singh, S. V., E-mail: satyavir@iigs.iigm.res.in; Lakhina, G. S., E-mail: lakhina@iigs.iigm.res.in [University of the Western Cape, Bellville 7535, Cape-Town (South Africa); Indian Institute of Geomagnetism, New Panvel (W), Navi Mumbai 410218 (India)

    2016-03-15

    Finite amplitude nonlinear ion-acoustic solitons, double layers, and supersolitons in a magnetized two-component plasma composed of adiabatic warm ions fluid and energetic nonthermal electrons are studied by employing the Sagdeev pseudopotential technique and assuming the charge neutrality condition at equilibrium. The model generates supersoliton structures at supersonic Mach numbers regime in addition to solitons and double layers, whereas in the unmagnetized two-component plasma case only, soliton and double layer solutions can be obtained. Further investigation revealed that wave obliqueness plays a critical role for the evolution of supersoliton structures in magnetized two-component plasmas. In addition, the effect of ion temperature and nonthermal energetic electron tends to decrease the speed of oscillation of the nonlinear electrostatic structures. The present theoretical results are compared with Viking satellite observations.

  16. Two component injection moulding: an interface quality and bond strength dilemma

    DEFF Research Database (Denmark)

    Islam, Mohammad Aminul; Hansen, Hans Nørgaard; Tang, Peter Torben

    2008-01-01

    on quality parameters of the two component parts. Most engineering applications of two component injection moulding calls for high bond strength between the two polymers, on the other hand a sharp and well-defined interface between the two polymers are required for applications like selective metallization...... of polymers, parts for micro applications and also for the aesthetic purpose of the final product. The investigation presented in this paper indicates a dilemma between obtaining reasonably good bond strength and at the same time keeping the interface quality suitable for applications. The required process...... conditions for a sharp and well-defined interface are exactly the opposite of what is congenial for higher bond strength. So in the production of two component injection moulded parts, there is a compromise to make between the interface quality and the bond strength of the two polymers. Also the injection...

  17. MP3 compression of Doppler ultrasound signals.

    Science.gov (United States)

    Poepping, Tamie L; Gill, Jeremy; Fenster, Aaron; Holdsworth, David W

    2003-01-01

    The effect of lossy, MP3 compression on spectral parameters derived from Doppler ultrasound (US) signals was investigated. Compression was tested on signals acquired from two sources: 1. phase quadrature and 2. stereo audio directional output. A total of 11, 10-s acquisitions of Doppler US signal were collected from each source at three sites in a flow phantom. Doppler signals were digitized at 44.1 kHz and compressed using four grades of MP3 compression (in kilobits per second, kbps; compression ratios in brackets): 1400 kbps (uncompressed), 128 kbps (11:1), 64 kbps (22:1) and 32 kbps (44:1). Doppler spectra were characterized by peak velocity, mean velocity, spectral width, integrated power and ratio of spectral power between negative and positive velocities. The results suggest that MP3 compression on digital Doppler US signals is feasible at 128 kbps, with a resulting 11:1 compression ratio, without compromising clinically relevant information. Higher compression ratios led to significant differences for both signal sources when compared with the uncompressed signals. Copyright 2003 World Federation for Ultrasound in Medicine & Biology

  18. MODELING THERMAL DUST EMISSION WITH TWO COMPONENTS: APPLICATION TO THE PLANCK HIGH FREQUENCY INSTRUMENT MAPS

    International Nuclear Information System (INIS)

    Meisner, Aaron M.; Finkbeiner, Douglas P.

    2015-01-01

    We apply the Finkbeiner et al. two-component thermal dust emission model to the Planck High Frequency Instrument maps. This parameterization of the far-infrared dust spectrum as the sum of two modified blackbodies (MBBs) serves as an important alternative to the commonly adopted single-MBB dust emission model. Analyzing the joint Planck/DIRBE dust spectrum, we show that two-component models provide a better fit to the 100-3000 GHz emission than do single-MBB models, though by a lesser margin than found by Finkbeiner et al. based on FIRAS and DIRBE. We also derive full-sky 6.'1 resolution maps of dust optical depth and temperature by fitting the two-component model to Planck 217-857 GHz along with DIRBE/IRAS 100 μm data. Because our two-component model matches the dust spectrum near its peak, accounts for the spectrum's flattening at millimeter wavelengths, and specifies dust temperature at 6.'1 FWHM, our model provides reliable, high-resolution thermal dust emission foreground predictions from 100 to 3000 GHz. We find that, in diffuse sky regions, our two-component 100-217 GHz predictions are on average accurate to within 2.2%, while extrapolating the Planck Collaboration et al. single-MBB model systematically underpredicts emission by 18.8% at 100 GHz, 12.6% at 143 GHz, and 7.9% at 217 GHz. We calibrate our two-component optical depth to reddening, and compare with reddening estimates based on stellar spectra. We find the dominant systematic problems in our temperature/reddening maps to be zodiacal light on large angular scales and the cosmic infrared background anisotropy on small angular scales

  19. The phenomenon of Doppler

    International Nuclear Information System (INIS)

    Stoll, I.; Seidlerova, I.; Schwippel, J.; Poss, O.; Solc, M.

    1992-01-01

    The book is devoted to the life and work of Christian Doppler and particularly to his links to Prague and to the Slovak town of Banska Stiavnica. Many historical facts concerning Doppler's activities as well as the history of physics and astronomy are collected. Information is also presented about the Czech Technical University, the Society of Czechoslovak Mathematicians and Physicists, the Czechoslovak Astronomical Society, the Czechoslovak Spectroscopic Society and the Czechoslovak Society for the History of Science and Technology. The publication is amply supplemented with historical pictorial material (M.D.). 92 figs., 82 refs

  20. Doppler radar physiological sensing

    CERN Document Server

    Lubecke, Victor M; Droitcour, Amy D; Park, Byung-Kwon; Singh, Aditya

    2016-01-01

    Presents a comprehensive description of the theory and practical implementation of Doppler radar-based physiological monitoring. This book includes an overview of current physiological monitoring techniques and explains the fundamental technology used in remote non-contact monitoring methods. Basic radio wave propagation and radar principles are introduced along with the fundamentals of physiological motion and measurement. Specific design and implementation considerations for physiological monitoring radar systems are then discussed in detail. The authors address current research and commercial development of Doppler radar based physiological monitoring for healthcare and other applications.

  1. Doppler ion program description

    International Nuclear Information System (INIS)

    Henline, P.

    1980-12-01

    The Doppler spectrometer is a conventional Czerny-Turner grating spectrometer with a 1024 channel multiple detector. Light is dispersed across the detector, and its output yields a spectrum covering approximately 200 A. The width of the spectral peak is directly proportional to the temperature of the emitting ions, and determination of the impurity ion temperature allows one to infer the plasma ion temperature. The Doppler ion software system developed at General Atomic uses a TRACOR Northern 1710-31 and an LSI-11/2. The exact configuration of Doublet III is different from TRACOR Northern systems at other facilities

  2. Pulse Doppler radar

    CERN Document Server

    Alabaster, Clive

    2012-01-01

    This book is a practitioner's guide to all aspects of pulse Doppler radar. It concentrates on airborne military radar systems since they are the most used, most complex, and most interesting of the pulse Doppler radars; however, ground-based and non-military systems are also included. It covers the fundamental science, signal processing, hardware issues, systems design and case studies of typical systems. It will be a useful resource for engineers of all types (hardware, software and systems), academics, post-graduate students, scientists in radar and radar electronic warfare sectors and milit

  3. Spectroscopic Doppler analysis for visible-light optical coherence tomography

    Science.gov (United States)

    Shu, Xiao; Liu, Wenzhong; Duan, Lian; Zhang, Hao F.

    2017-12-01

    Retinal oxygen metabolic rate can be effectively measured by visible-light optical coherence tomography (vis-OCT), which simultaneously quantifies oxygen saturation and blood flow rate in retinal vessels through spectroscopic analysis and Doppler measurement, respectively. Doppler OCT relates phase variation between sequential A-lines to the axial flow velocity of the scattering medium. The detectable phase shift is between -π and π due to its periodicity, which limits the maximum measurable unambiguous velocity without phase unwrapping. Using shorter wavelengths, vis-OCT is more vulnerable to phase ambiguity since flow induced phase variation is linearly related to the center wavenumber of the probing light. We eliminated the need for phase unwrapping using spectroscopic Doppler analysis. We split the whole vis-OCT spectrum into a series of narrow subbands and reconstructed vis-OCT images to extract corresponding Doppler phase shifts in all the subbands. Then, we quantified flow velocity by analyzing subband-dependent phase shift using linear regression. In the phantom experiment, we showed that spectroscopic Doppler analysis extended the measurable absolute phase shift range without conducting phase unwrapping. We also tested this method to quantify retinal blood flow in rodents in vivo.

  4. Two-component HLMC-gas flow instability and inhomogeneity phenomena in open-pool reactor

    International Nuclear Information System (INIS)

    Sergey I Shcherbakov

    2005-01-01

    Full text of publication follows: Consideration is being given to two-component gas-liquid flows with inhomogeneous gas content. The inhomogeneity of gas content over flow space can be caused by local mixing of gas and liquid, gas injection, gas-containing liquid jet penetration into the bulk of liquid without gas. The paper presents the computational results obtained using the direct non-stationary calculation with the TURBO-FLOW computer code. The results refer to flows near the liquid level, flows in downcomer gaps, collectors, elements with varying geometry (jet outlet into space, flow turn) for the pool-type reactors and experimental models. The following processes have been shown and discussed: formation of new liquid levels, entrainment of gas from the level, change in density composition of gas, flow stratification, effect of gas emergence rate and density convection on flow pattern. At gas phase transfer by liquid, two phenomena governing this transfer proceed: gas slip in liquid and density convection of non-uniformly aerated liquid. In horizontal flows, a vertical stratification of gas content always occurs. If the flow changes its direction to an upward one (collector at core inlet), the gas content maximum would be observed in channels nearest to the inlet. At the liquid level, the processes of gas separation from liquid and gas entrainment take place. The separation is a self-sustained process due to circulations arising near the level. The rate of gas entrainment is proportional to the rate of overflow and inversely proportional to the height of liquid level. At the downcomer region in case of its expansion, there occurs the instability of flow resulting in formation of liquid level and falling jet. The level is lower the more the gas content at inlet. The accumulation of gas occurs at sharp turns, encumbered regions (tube bundle), at all regions with upper (ceiling) constraints of flow. The flow instability being often observed in gas-liquid flows

  5. Doppler evaluation of valvular stenosis

    International Nuclear Information System (INIS)

    Kisslo, J.; Krafchek, J.; Adams, D.; Mark, D.B.

    1986-01-01

    One of the reasons why use of Doppler echocardiography is growing rapidly is because of its utility in detecting the presence of valvular stenosis and in estimating its severity. Detection of the presence of stenotic valvular heart disease using Doppler echocardiography was originally described over 10 years ago. It has been demonstrated that Doppler blood velocity data could be used to estimate the severity of a stenotic lesion. This chapter discusses the evaluation of valvular stenois using Doppler

  6. Density profiles and collective excitations of a trapped two-component Fermi vapour

    International Nuclear Information System (INIS)

    Amoruso, M.; Meccoli, I.; Minguzzi, A.; Tosi, M.P.

    1999-08-01

    We discuss the ground state and the small-amplitude excitations of a degenerate vapour of fermionic atoms placed in two hyperfine states inside a spherical harmonic trap. An equations-of-motion approach is set up to discuss the hydrodynamic dissipation processes from the interactions between the two components of the fluid beyond mean-field theory and to emphasize analogies with spin dynamics and spin diffusion in a homogeneous Fermi liquid. The conditions for the establishment of a collisional regime via scattering against cold-atom impurities are analyzed. The equilibrium density profiles are then calculated for a two-component vapour of 40 K atoms: they are little modified by the interactions for presently relevant values of the system parameters, but spatial separation of the two components will spontaneously arise as the number of atoms in the trap is increased. The eigenmodes of collective oscillation in both the total particle number density and the concentration density are evaluated analytically in the special case of a symmetric two-component vapour in the collisional regime. The dispersion relation of the surface modes for the total particle density reduces in this case to that of a one-component Fermi vapour, whereas the frequencies of all other modes are shifted by the interactions. (author)

  7. The essential YycFG two-component system controls cell wall metabolism in Bacillus subtilis

    DEFF Research Database (Denmark)

    Bisicchia, Paola; Noone, David; Lioliou, Efthimia

    2007-01-01

    Adaptation of bacteria to the prevailing environmental and nutritional conditions is often mediated by two-component signal transduction systems (TCS). The Bacillus subtilis YycFG TCS has attracted special attention as it is essential for viability and its regulon is poorly defined. Here we show...

  8. Two component system that regulates methanol and formaldehyde oxidation in Paracoccus denitrificans.

    NARCIS (Netherlands)

    Harms, N.; Reijnders, W.N.M.; Koning, S.; van Spanning, R.J.M.

    2001-01-01

    A chromosomal region encoding a two-component regulatory system, FlhRS, has been isolated from Paracoccus denitrificans. FlhRS-deficient mutants were unable to grow on methanol, methylamine, or choline as the carbon and energy source. Expression of the gene encoding glutathione-dependent

  9. Two-component system that regulates methanol and formaldehyde oxidation in Paracoccus denitrificans.

    NARCIS (Netherlands)

    Harms, N.; Reijnders, W.N.M.; Koning, S.; van Spanning, R.J.M.

    2001-01-01

    A chromosomal region encoding a two-component regulatory system, FlhRS, has been isolated from Paracoccus denitrificans. FlhRS-deficient mutants were unable to grow on methanol, methylamine, or choline as the carbon and energy source. Expression of the gene encoding glutathione-dependent

  10. A novel two-component system involved in secretion stress response in Streptomyces lividans.

    Directory of Open Access Journals (Sweden)

    Sonia Gullón

    Full Text Available BACKGROUND: Misfolded proteins accumulating outside the bacterial cytoplasmic membrane can interfere with the secretory machinery, hence the existence of quality factors to eliminate these misfolded proteins is of capital importance in bacteria that are efficient producers of secretory proteins. These bacteria normally use a specific two-component system to respond to the stress produced by the accumulation of the misfolded proteins, by activating the expression of HtrA-like proteases to specifically eliminate the incorrectly folded proteins. METHODOLOGY/PRINCIPAL FINDINGS: Overproduction of alpha-amylase in S. lividans causing secretion stress permitted the identification of a two-component system (SCO4156-SCO4155 that regulates three HtrA-like proteases which appear to be involved in secretion stress response. Mutants in each of the genes forming part of the two-genes operon that encodes the sensor and regulator protein components accumulated misfolded proteins outside the cell, strongly suggesting the involvement of this two-component system in the S. lividans secretion stress response. CONCLUSIONS/SIGNIFICANCE: To our knowledge this is the first time that a specific secretion stress response two-component system is found to control the expression of three HtrA-like protease genes in S. lividans, a bacterium that has been repeatedly used as a host for the synthesis of homologous and heterologous secretory proteins of industrial application.

  11. A two-component dark matter model with real singlet scalars ...

    Indian Academy of Sciences (India)

    Theoretical framework. In the present work, the dark matter candidate has two components S and S′ both of ... The scalar sector potential (for Higgs and two real singlet scalars) in this framework can then be written .... In this work we obtain the allowed values of model parameters (δ2, δ′2, MS and M′S) using three direct ...

  12. Design of a Novel Two-Component Hybrid Dermal Scaffold for the Treatment of Pressure Sores.

    Science.gov (United States)

    Sharma, Vaibhav; Kohli, Nupur; Moulding, Dale; Afolabi, Halimat; Hook, Lilian; Mason, Chris; García-Gareta, Elena

    2017-11-01

    The aim of this study is to design a novel two-component hybrid scaffold using the fibrin/alginate porous hydrogel Smart Matrix combined to a backing layer of plasma polymerized polydimethylsiloxane (Sil) membrane to make the fibrin-based dermal scaffold more robust for the treatment of the clinically challenging pressure sores. A design criteria are established, according to which the Sil membranes are punched to avoid collection of fluid underneath. Manual peel test shows that native silicone does not attach to the fibrin/alginate component while the plasma polymerized silicone membranes are firmly bound to fibrin/alginate. Structural characterization shows that the fibrin/alginate matrix is intact after the addition of the Sil membrane. By adding a Sil membrane to the original fibrin/alginate scaffold, the resulting two-component scaffolds have a significantly higher shear or storage modulus G'. In vitro cell studies show that dermal fibroblasts remain viable, proliferate, and infiltrate the two-component hybrid scaffolds during the culture period. These results show that the design of a novel two-component hybrid dermal scaffold is successful according to the proposed design criteria. To the best of the authors' knowledge, this is the first study that reports the combination of a fibrin-based scaffold with a plasma-polymerized silicone membrane. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Correlation inequalities for two-component hypercubic φ4 models. Pt. 2

    International Nuclear Information System (INIS)

    Soria, J.L.; Instituto Tecnologico de Tijuana

    1990-01-01

    We continue the program started in the first paper (J. Stat. Phys. 52 (1988) 711-726). We find new and already known correlation inequalities for a family of two-component hypercubic φ 4 models, using techniques of rotated correlation inequalities and random walk representation. (orig.)

  14. Multiple Two-Component Systems of Streptococcus mutans Regulate Agmatine Deiminase Gene Expression and Stress Tolerance▿

    OpenAIRE

    Liu, Yaling; Burne, Robert A.

    2009-01-01

    Induction of the agmatine deiminase system (AgDS) of Streptococcus mutans requires agmatine and is optimal at low pH. We show here that the VicRK, ComDE, and CiaRH two-component systems influence AgDS gene expression in response to acidic and thermal stresses.

  15. A two-component dark matter model with real singlet scalars ...

    Indian Academy of Sciences (India)

    2016-01-05

    Jan 5, 2016 ... We propose a two-component dark matter (DM) model, each component of which is a real singlet scalar, to explain results from both direct and indirect detection experiments. We put the constraints on the model parameters from theoretical bounds, PLANCK relic density results and direct DM experiments.

  16. The 27 Possible Intrinsic Symmetry Groups of Two-Component Links

    Directory of Open Access Journals (Sweden)

    Jason Parsley

    2012-02-01

    Full Text Available We consider the “intrinsic” symmetry group of a two-component link L, defined to be the image ∑(L of the natural homomorphism from the standard symmetry group MCG(S3, L to the product MCG(S3 × MCG(L. This group, first defined by Whitten in 1969, records directly whether L is isotopic to a link L′ obtained from L by permuting components or reversing orientations; it is a subgroup of Γ2, the group of all such operations. For two-component links, we catalog the 27 possible intrinsic symmetry groups, which represent the subgroups of Γ2 up to conjugacy. We are able to provide prime, nonsplit examples for 21 of these groups; some are classically known, some are new. We catalog the frequency at which each group appears among all 77,036 of the hyperbolic two-component links of 14 or fewer crossings in Thistlethwaite’s table. We also provide some new information about symmetry groups of the 293 non-hyperbolic two-component links of 14 or fewer crossings in the table.

  17. Light Responsive Two-Component Supramolecular Hydrogel: A Sensitive Platform for Humidity Sensors

    KAUST Repository

    Samai, Suman

    2016-02-15

    The supramolecular assembly of anionic azobenzene dicarboxylate and cationic cetyltrimethylammonium bromide (CTAB) formed a stimuli responsive hydrogel with a critical gelation concentration (CGC) of 0.33 wt%. This self-sustainable two-component system was able to repair damage upon light irradiation. Moreover, it was successfully employed in the fabrication of highly sensitive humidity sensors for the first time.

  18. Light Responsive Two-Component Supramolecular Hydrogel: A Sensitive Platform for Humidity Sensors

    KAUST Repository

    Samai, Suman; Sapsanis, Christos; Patil, Sachin; Ezzeddine, Alaa; Moosa, Basem; Omran, Hesham; Emwas, Abdul-Hamid M.; Salama, Khaled N.; Khashab, Niveen M.

    2016-01-01

    The supramolecular assembly of anionic azobenzene dicarboxylate and cationic cetyltrimethylammonium bromide (CTAB) formed a stimuli responsive hydrogel with a critical gelation concentration (CGC) of 0.33 wt%. This self-sustainable two-component system was able to repair damage upon light irradiation. Moreover, it was successfully employed in the fabrication of highly sensitive humidity sensors for the first time.

  19. New methods for the characterization of pyrocarbon; The two component model of pyrocarbon

    Energy Technology Data Exchange (ETDEWEB)

    Luhleich, H.; Sutterlin, L.; Hoven, H.; Nickel, H.

    1972-04-19

    In the first part, new experiments to clarify the origin of different pyrocarbon components are described. Three new methods (plasma-oxidation, wet-oxidation, ultrasonic method) are presented to expose the carbon black like component in the pyrocarbon deposited in fluidized beds. In the second part, a two component model of pyrocarbon is proposed and illustrated by examples.

  20. Doppler-musical instrument

    International Nuclear Information System (INIS)

    Sato, T.J.; Watanabe, N.

    2001-01-01

    We propose a possible ultra-high energy resolution backscattering spectrometer optimized to spallation neutron source. A combination of multi monochromator crystal and Doppler drive provides considerable neutron flux, together with the reasonable energy range -30 < E < 30 μeV, even when the ultra-high energy resolution of ΔE∼0.03 μeV is attained. (author)

  1. Scanning laser Doppler vibrometry

    DEFF Research Database (Denmark)

    Brøns, Marie; Thomsen, Jon Juel

    With a Scanning Laser Doppler Vibrometer (SLDV) a vibrating surface is automatically scanned over predefined grid points, and data processed for displaying vibration properties like mode shapes, natural frequencies, damping ratios, and operational deflection shapes. Our SLDV – a PSV-500H from...

  2. Method and system of doppler correction for mobile communications systems

    Science.gov (United States)

    Georghiades, Costas N. (Inventor); Spasojevic, Predrag (Inventor)

    1999-01-01

    Doppler correction system and method comprising receiving a Doppler effected signal comprising a preamble signal (32). A delayed preamble signal (48) may be generated based on the preamble signal (32). The preamble signal (32) may be multiplied by the delayed preamble signal (48) to generate an in-phase preamble signal (60). The in-phase preamble signal (60) may be filtered to generate a substantially constant in-phase preamble signal (62). A plurality of samples of the substantially constant in-phase preamble signal (62) may be accumulated. A phase-shifted signal (76) may also be generated based on the preamble signal (32). The phase-shifted signal (76) may be multiplied by the delayed preamble signal (48) to generate an out-of-phase preamble signal (80). The out-of-phase preamble signal (80) may be filtered to generate a substantially constant out-of-phase preamble signal (82). A plurality of samples of the substantially constant out-of-phase signal (82) may be accumulated. A sum of the in-phase preamble samples and a sum of the out-of-phase preamble samples may be normalized relative to each other to generate an in-phase Doppler estimator (92) and an out-of-phase Doppler estimator (94).

  3. Remote Sensing of Complex Flows by Doppler Wind Lidar: Summary of Issues and Preliminary Recommendations from IEA Wind Task 32 Phase 1

    Energy Technology Data Exchange (ETDEWEB)

    Clifton, Andrew

    2017-06-21

    IEA Wind Task 32 seeks to identify and mitigate the barriers to the adoption of lidar for wind energy applications. In Phase 1 of the task, a working group looked at the state of the art of wind lidar in complex flow conditions. This presentation is a short summary of that work, given at the start of Phase 2.

  4. The YvfTU Two-component System is involved in plcR expression in Bacillus cereus

    Directory of Open Access Journals (Sweden)

    Nguyen-the Christophe

    2008-10-01

    Full Text Available Abstract Background Most extracellular virulence factors produced by Bacillus cereus are regulated by the pleiotropic transcriptional activator PlcR. Among strains belonging to the B. cereus group, the plcR gene is always located in the vicinity of genes encoding the YvfTU two-component system. The putative role of YvfTU in the expression of the PlcR regulon was therefore investigated. Results Expression of the plcR gene was monitored using a transcriptional fusion with a lacZ reporter gene in a yvfTU mutant and in its B. cereus ATCC 14579 parental strain. Two hours after the onset of the stationary phase, a stage at which the PlcR regulon is highly expressed, the plcR expression in the yvfTU mutant was only 50% of that of its parental strain. In addition to the reduced plcR expression in the yvfTU mutant, a few members of the PlcR regulon showed a differential expression, as revealed by transcriptomic and proteomic analyses. The virulence of the yvfTU mutant in a Galleria mellonella insect model was slightly lower than that of the parental strain. Conclusion The YvfTU two-component system is not required for the expression of most of the virulence factors belonging to the PlcR regulon. However, YvfTU is involved in expression of plcR, a major regulator of virulence in B. cereus.

  5. Preventive effect of two-component chemical radioprotector and variability in its application

    International Nuclear Information System (INIS)

    Lambov, V.; Metodiev, S.

    1993-01-01

    The purpose of the study is to evaluate the radioprotective efficiency of two-component radioprotective schema consisting of the chemically synthesized radioprotector WR-2721 (OK-79) and a new glycoside pigment obtained from melanoidine CL. The application of melanoidine 7-21 days before WR-2721 significantly increases the radioprotective efficiency of the chemically obtained product and enhances the 30-day survival of hybrid mice treated with 15 Gy whole body gamma irradiation. The effect of potentiated radioprotection is not observed when the interval between the application of the two agents is reduced to 24 h. It is suggested that the observed enhancement of the radioprotective efficiency in the two-component schema is due to the antioxidant and immuno modulating properties of the pigment product, observed and described in our previous investigations. (author)

  6. A hybrid two-component Bose–Einstein condensate interferometer for measuring magnetic field gradients

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Fei [Key Laboratory of Fiber Optic Sensing Technology and Information Processing, Ministry of Education, Wuhan University of Technology, Wuhan 430070 (China); Huang, Jiahao, E-mail: hjiahao@mail2.sysu.edu.cn [TianQin Research Center & School of Physics and Astronomy, Sun Yat-Sen University, SYSU Zhuhai Campus, Zhuhai 519082 (China); Liu, Quan [Key Laboratory of Fiber Optic Sensing Technology and Information Processing, Ministry of Education, Wuhan University of Technology, Wuhan 430070 (China)

    2017-03-03

    Highlights: • A scheme for detecting magnetic field gradients via a double-well two-component Bose–Einstein condensate interferometer. • The magnetic field gradient can be extracted by either the spin population or the external state. • Our proposal is potentially sensitive to weak magnetic field inhomogeneity due to its small sensor size. - Abstract: We have proposed a scheme to detect magnetic field gradients via an interferometer based on a double-well two-component Bose–Einstein condensate (BEC). Utilizing a sequence of quantum control operations on both external and internal degree of the BEC, one can extract the magnetic field gradients by measuring either the population in one component or the fidelity between the final external state and the initial ground state. Our scheme can be implemented by current experimental techniques of manipulating ultracold atoms.

  7. Competitive adsorption of a two-component gas on a deformable adsorbent

    International Nuclear Information System (INIS)

    Usenko, A S

    2014-01-01

    We investigate the competitive adsorption of a two-component gas on the surface of an adsorbent whose adsorption properties vary due to the adsorbent deformation. The essential difference of adsorption isotherms for a deformable adsorbent both from the classical Langmuir adsorption isotherms of a two-component gas and from the adsorption isotherms of a one-component gas is obtained, taking into account variations in the adsorption properties of the adsorbent in adsorption. We establish bistability and tristability of the system caused by variations in adsorption properties of the adsorbent in competitive adsorption of gas particles on it. We derive conditions under which adsorption isotherms of a binary gas mixture have two stable asymptotes. It is shown that the specific features of the behavior of the system under study can be described in terms of a potential of the known explicit form. (paper)

  8. Multistability in an optomechanical system with a two-component Bose-Einstein condensate

    International Nuclear Information System (INIS)

    Dong Ying; Ye Jinwu; Pu Han

    2011-01-01

    We investigate a system consisting of a two-component Bose-Einstein condensate interacting dispersively with a Fabry-Perot optical cavity where the two components of the condensate are resonantly coupled to each other by another classical field. The key feature of this system is that the atomic motional degrees of freedom and the internal pseudospin degrees of freedom are coupled to the cavity field simultaneously, hence an effective spin-orbital coupling within the condensate is induced by the cavity. The interplay among the atomic center-of-mass motion, the atomic collective spin, and the cavity field leads to a strong nonlinearity, resulting in multistable behavior in both matter wave and light wave at the few-photon level.

  9. The role of the Kubo number in two-component turbulence

    International Nuclear Information System (INIS)

    Qin, G.; Shalchi, A.

    2013-01-01

    We explore the random walk of magnetic field lines in two-component turbulence by using computer simulations. It is often assumed that the two-component model provides a good approximation for solar wind turbulence. We explore the dependence of the field line diffusion coefficient on the Kubo number which is a fundamental and characteristic quantity in the theory of turbulence. We show that there are two transport regimes. One is the well-known quasilinear regime in which the diffusion coefficient is proportional to the Kubo number squared, and the second one is a nonlinear regime in which the diffusion coefficient is directly proportional to the Kubo number. The so-called percolative transport regime which is often discussed in the literature cannot be found. The numerical results obtained in the present paper confirm analytical theories for random walking field lines developed in the past

  10. Theoretical calculation of cryogenic distillation for two-component hydrogen isotope system

    International Nuclear Information System (INIS)

    Xia Xiulong; Luo Yangming; Wang Heyi; Fu Zhonghua; Liu Jun; Han Jun; Gu Mei

    2005-10-01

    Cryogenic distillation model for single column was built to simulating hydrogen isotope separation system. Three two-component system H 2 /HD, H 2 /HT and D 2 /DT was studied. Both temperature and concentration distribution was obtained and the results show a clear separation characteristics. H 2 /HT has the best separation performance while D 2 /DT was the most difficult to separate. (authors)

  11. Nutrition quality, body size and two components of mating behavior in Drosophila melanogaster.

    Science.gov (United States)

    Pavković-Lucić, Sofija; Kekić, Vladimir

    2010-01-01

    Two components of mating behavior, mating latency and duration of copulation, were investigated in Drosophila melanogaster males from three different "nutritional" strains, reared for more than 35 generations on banana, tomato and cornmeal-agar-yeast substrates. Males from different strains did not differ according to mating latency and duration of copulation. Also, the sizes of males from different strains did not contribute to these behavioral traits.

  12. A two-component generalized extreme value distribution for precipitation frequency analysis

    Czech Academy of Sciences Publication Activity Database

    Rulfová, Zuzana; Buishand, A.; Roth, M.; Kyselý, Jan

    2016-01-01

    Roč. 534, March (2016), s. 659-668 ISSN 0022-1694 R&D Projects: GA ČR(CZ) GA14-18675S Institutional support: RVO:68378289 Keywords : precipitation extremes * two-component extreme value distribution * regional frequency analysis * convective precipitation * stratiform precipitation * Central Europe Subject RIV: DG - Athmosphere Sciences, Meteorology Impact factor: 3.483, year: 2016 http://www.sciencedirect.com/science/article/pii/S0022169416000500

  13. Two-component bond for coating materials coming into contact with radioactivity

    International Nuclear Information System (INIS)

    Svoboda, L.; Fajfr, K.

    1989-01-01

    The two-component bonding agent consists of an epoxy resin of the diane-bis-glycidyl ether type and an amine hardener containing benzyl alcohol and bis-2-ethylhexyl phthalate. The claimed bond features high radiation stability and very good decontaminability. Thanks to low viscosity of the bond, pigmented reactor-plastics can be prepared. The procedure is described of applying the bond onto a concrete surface. (E.S.)

  14. Role of Streptococcus mutans two-component systems in antimicrobial peptide resistance in the oral cavity

    OpenAIRE

    Kawada-Matsuo, Miki; Komatsuzawa, Hitoshi

    2017-01-01

    Summary Approximately 100 trillion microorganisms exist in the oral cavity. For the commensal bacteria of the oral cavity, it is important to adapt to environmental stimuli, including human- or bacteria-derived antimicrobial agents. Recently, bacterial-specific signal transduction regulatory systems, called two-component systems (TCSs), which appear to be focused on sensing and adapting to the environment, were discovered. Streptococcus mutans is an oral commensal bacteria and is also known a...

  15. Molecular Orientation in Two Component Vapor-Deposited Glasses: Effect of Substrate Temperature and Molecular Shape

    Science.gov (United States)

    Powell, Charles; Jiang, Jing; Walters, Diane; Ediger, Mark

    Vapor-deposited glasses are widely investigated for use in organic electronics including the emitting layers of OLED devices. These materials, while macroscopically homogenous, have anisotropic packing and molecular orientation. By controlling this orientation, outcoupling efficiency can be increased by aligning the transition dipole moment of the light-emitting molecules parallel to the substrate. Light-emitting molecules are typically dispersed in a host matrix, as such, it is imperative to understand molecular orientation in two-component systems. In this study we examine two-component vapor-deposited films and the orientations of the constituent molecules using spectroscopic ellipsometry, UV-vis and IR spectroscopy. The role of temperature, composition and molecular shape as it effects molecular orientation is examined for mixtures of DSA-Ph in Alq3 and in TPD. Deposition temperature relative to the glass transition temperature of the two-component mixture is the primary controlling factor for molecular orientation. In mixtures of DSA-Ph in Alq3, the linear DSA-Ph has a horizontal orientation at low temperatures and slight vertical orientation maximized at 0.96Tg,mixture, analogous to one-component films.

  16. The Umov effect in application to an optically thin two-component cloud of cosmic dust

    Science.gov (United States)

    Zubko, Evgenij; Videen, Gorden; Zubko, Nataliya; Shkuratov, Yuriy

    2018-04-01

    The Umov effect is an inverse correlation between linear polarization of the sunlight scattered by an object and its geometric albedo. The Umov effect has been observed in particulate surfaces, such as planetary regoliths, and recently it also was found in single-scattering small dust particles. Using numerical modeling, we study the Umov effect in a two-component mixture of small irregularly shaped particles. Such a complex chemical composition is suggested in cometary comae and other types of optically thin clouds of cosmic dust. We find that the two-component mixtures of small particles also reveal the Umov effect regardless of the chemical composition of their end-member components. The interrelation between log(Pmax) and log(A) in a two-component mixture of small irregularly shaped particles appears either in a straight linear form or in a slightly curved form. This curvature tends to decrease while the index n in a power-law size distribution r-n grows; at n > 2.5, the log(Pmax)-log(A) diagrams are almost straight linear in appearance. The curvature also noticeably decreases with the packing density of constituent material in irregularly shaped particles forming the mixture. That such a relation exists suggest the Umov effect may also be observed in more complex mixtures.

  17. Doppler-musical instrument

    Energy Technology Data Exchange (ETDEWEB)

    Sato, T.J. [National Research Institute for Metals, Tsukuba, Ibaraki (Japan); Watanabe, N. [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Shibata, K. [Institute for Materials Research, Tohoku Univ., Sendai, Miyagi (Japan)

    2001-03-01

    We propose a possible ultra-high energy resolution backscattering spectrometer optimized to spallation neutron source. A combination of multi monochromator crystal and Doppler drive provides considerable neutron flux, together with the reasonable energy range -30 < E < 30 {mu}eV, even when the ultra-high energy resolution of {delta}E{approx}0.03 {mu}eV is attained. (author)

  18. Laser doppler velocimetry and confined flows

    Directory of Open Access Journals (Sweden)

    Ilić Jelena T.

    2017-01-01

    Full Text Available Finding the mode, in which two component laser Doppler velocimetry can be applied to flows confined in cylindrical tubes or vessels, was the aim of this study. We have identified principle issues that influence the propagation of laser beams in laser Doppler velocimetry system, applied to flow confined in cylindrical tube. Among them, the most important are influences of fluid and wall refractive indices, wall thickness and internal radius ratio and beam intersection angle. In analysis of the degrees of these influences, we have applied mathematical model, based on geometrical optics. The separation of measurement volumes, that measure different velocity components, has been recognized as the main drawback. To overcome this, we propose a lens with dual focal length – primary focal length for the measurement of one velocity component and secondary focal length for the measurement of the other velocity component. We present here the procedure for calculating the optimal value of secondary focal length, depending on experimental set-up parameters. The mathematical simulation of the application of the dual focal length lens, for chosen cases presented here, confirmed the accuracy of the proposed procedure.

  19. Complex regression Doppler optical coherence tomography

    Science.gov (United States)

    Elahi, Sahar; Gu, Shi; Thrane, Lars; Rollins, Andrew M.; Jenkins, Michael W.

    2018-04-01

    We introduce a new method to measure Doppler shifts more accurately and extend the dynamic range of Doppler optical coherence tomography (OCT). The two-point estimate of the conventional Doppler method is replaced with a regression that is applied to high-density B-scans in polar coordinates. We built a high-speed OCT system using a 1.68-MHz Fourier domain mode locked laser to acquire high-density B-scans (16,000 A-lines) at high enough frame rates (˜100 fps) to accurately capture the dynamics of the beating embryonic heart. Flow phantom experiments confirm that the complex regression lowers the minimum detectable velocity from 12.25 mm / s to 374 μm / s, whereas the maximum velocity of 400 mm / s is measured without phase wrapping. Complex regression Doppler OCT also demonstrates higher accuracy and precision compared with the conventional method, particularly when signal-to-noise ratio is low. The extended dynamic range allows monitoring of blood flow over several stages of development in embryos without adjusting the imaging parameters. In addition, applying complex averaging recovers hidden features in structural images.

  20. VfrB Is a Key Activator of the Staphylococcus aureus SaeRS Two-Component System.

    Science.gov (United States)

    Krute, Christina N; Rice, Kelly C; Bose, Jeffrey L

    2017-03-01

    In previous studies, we identified the fatty acid kinase virulence factor regulator B (VfrB) as a potent regulator of α-hemolysin and other virulence factors in Staphylococcus aureus In this study, we demonstrated that VfrB is a positive activator of the SaeRS two-component regulatory system. Analysis of vfrB , saeR , and saeS mutant strains revealed that VfrB functions in the same pathway as SaeRS. At the transcriptional level, the promoter activities of SaeRS class I ( coa ) and class II ( hla ) target genes were downregulated during the exponential growth phase in the vfrB mutant, compared to the wild-type strain. In addition, saePQRS expression was decreased in the vfrB mutant strain, demonstrating a need for this protein in the autoregulation of SaeRS. The requirement for VfrB-mediated activation was circumvented when SaeS was constitutively active due to an SaeS (L18P) substitution. Furthermore, activation of SaeS via human neutrophil peptide 1 (HNP-1) overcame the dependence on VfrB for transcription from class I Sae promoters. Consistent with the role of VfrB in fatty acid metabolism, hla expression was decreased in the vfrB mutant with the addition of exogenous myristic acid. Lastly, we determined that aspartic acid residues D38 and D40, which are predicted to be key to VfrB enzymatic activity, were required for VfrB-mediated α-hemolysin production. Collectively, this study implicates VfrB as a novel accessory protein needed for the activation of SaeRS in S. aureus IMPORTANCE The SaeRS two-component system is a key regulator of virulence determinant production in Staphylococcus aureus Although the regulon of this two-component system is well characterized, the activation mechanisms, including the specific signaling molecules, remain elusive. Elucidating the complex regulatory circuit of SaeRS regulation is important for understanding how the system contributes to disease causation by this pathogen. To this end, we have identified the fatty acid kinase

  1. Correlation inequalities for two-component hypercubic /varreverse arrowphi/4 models

    International Nuclear Information System (INIS)

    Soria, J.L.

    1988-01-01

    A collection of new and already known correlation inequalities is found for a family of two-component hypercubic /varreverse arrowphi/ 4 models, using techniques of duplicated variables, rotated correlation inequalities, and random walk representation. Among the interesting new inequalities are: rotated very special Dunlop-Newman inequality 2 ; /varreverse arrowphi//sub 1z/ 2 + /varreverse arrowphi//sub 2z/ 2 ≥ 0, rotated Griffiths I inequality 2 - /varreverse arrowphi//sub 2z/ 2 > ≥ 0, and anti-Lebowitz inequality u 4 1111 ≥ 0

  2. Chemically reacting flow of a compressible thermally radiating two-component plasma

    International Nuclear Information System (INIS)

    Bestman, A.R.

    1990-12-01

    The paper studies the compressible flow of a hot two-component plasma in the presence of gravitation and chemical reaction in a vertical channel. For the optically thick gas approximation, closed form analytical solutions are possible. Asymptotic solutions are also obtained for the general differential approximation when the temperature of the two bounding walls are the same. In the general case the problem is reduced to the solution of standard nonlinear integral equations which can be tackled by iterative procedure. The results are discussed quantitatively. The problem may be applicable to the understanding of explosive hydrogen-burning model of solar flares. (author). 6 refs, 4 figs

  3. The Two-Component Virial Theorem and the Physical Properties of Stellar Systems.

    Science.gov (United States)

    Dantas; Ribeiro; Capelato; de Carvalho RR

    2000-01-01

    Motivated by present indirect evidence that galaxies are surrounded by dark matter halos, we investigate whether their physical properties can be described by a formulation of the virial theorem that explicitly takes into account the gravitational potential term representing the interaction of the dark halo with the baryonic or luminous component. Our analysis shows that the application of such a "two-component virial theorem" not only accounts for the scaling relations displayed by, in particular, elliptical galaxies, but also for the observed properties of all virialized stellar systems, ranging from globular clusters to galaxy clusters.

  4. An infinite-order two-component relativistic Hamiltonian by a simple one-step transformation.

    Science.gov (United States)

    Ilias, Miroslav; Saue, Trond

    2007-02-14

    The authors report the implementation of a simple one-step method for obtaining an infinite-order two-component (IOTC) relativistic Hamiltonian using matrix algebra. They apply the IOTC Hamiltonian to calculations of excitation and ionization energies as well as electric and magnetic properties of the radon atom. The results are compared to corresponding calculations using identical basis sets and based on the four-component Dirac-Coulomb Hamiltonian as well as Douglas-Kroll-Hess and zeroth-order regular approximation Hamiltonians, all implemented in the DIRAC program package, thus allowing a comprehensive comparison of relativistic Hamiltonians within the finite basis approximation.

  5. Evaluation of solution stability for two-component polydisperse systems by small-angle scattering

    Science.gov (United States)

    Kryukova, A. E.; Konarev, P. V.; Volkov, V. V.

    2017-12-01

    The article is devoted to the modelling of small-angle scattering data using the program MIXTURE designed for the study of polydisperse multicomponent mixtures. In this work we present the results of solution stability studies for theoretical small-angle scattering data sets from two-component models. It was demonstrated that the addition of the noise to the data influences the stability range of the restored structural parameters. The recommendations for the optimal minimization schemes that permit to restore the volume size distributions for polydisperse systems are suggested.

  6. Simple waves in a two-component Bose-Einstein condensate

    Science.gov (United States)

    Ivanov, S. K.; Kamchatnov, A. M.

    2018-04-01

    We study the dynamics of so-called simple waves in a two-component Bose-Einstein condensate. The evolution of the condensate is described by Gross-Pitaevskii equations which can be reduced for these simple wave solutions to a system of ordinary differential equations which coincide with those derived by Ovsyannikov for the two-layer fluid dynamics. We solve the Ovsyannikov system for two typical situations of large and small difference between interspecies and intraspecies nonlinear interaction constants. Our analytic results are confirmed by numerical simulations.

  7. Two-component injection moulding simulation of ABS-POM micro structured surfaces

    DEFF Research Database (Denmark)

    Tosello, Guido; Hansen, Hans Nørgaard; Islam, Aminul

    2013-01-01

    Multi-component micro injection moulding (μIM) processes such as two-component (2k) μIM are the key technologies for the mass fabrication of multi-material micro products. 2k-μIM experiments involving a miniaturized test component with micro features in the sub-mm dimensional range and moulding...... a pair of thermoplastic materials (ABS and POM) were conducted. Three dimensional process simulations based on the finite element method have been performed to explore the capability of predicting filling pattern shape at component-level and surface micro feature-level in a polymer/polymer overmoulding...

  8. Dynamics of a strongly driven two-component Bose-Einstein condensate

    International Nuclear Information System (INIS)

    Salmond, G.L.; Holmes, C.A.; Milburn, G.J.

    2002-01-01

    We consider a two-component Bose-Einstein condensate in two spatially localized modes of a double-well potential, with periodic modulation of the tunnel coupling between the two modes. We treat the driven quantum field using a two-mode expansion and define the quantum dynamics in terms of the Floquet Operator for the time periodic Hamiltonian of the system. It has been shown that the corresponding semiclassical mean-field dynamics can exhibit regions of regular and chaotic motion. We show here that the quantum dynamics can exhibit dynamical tunneling between regions of regular motion, centered on fixed points (resonances) of the semiclassical dynamics

  9. Morphology-tunable and photoresponsive properties in a self-assembled two-component gel system.

    Science.gov (United States)

    Zhou, Yifeng; Xu, Miao; Yi, Tao; Xiao, Shuzhang; Zhou, Zhiguo; Li, Fuyou; Huang, Chunhui

    2007-01-02

    Photoresponsive C3-symmetrical trisurea self-assembling building blocks containing three azobenzene groups (LC10 and LC4) at the rim were designed and synthesized. By introducing a trisamide gelator (G18), which can self-aggregate through hydrogen bonds of acylamino moieties to form a fibrous network, the mixture of LC10 (or LC4) and G18 forms an organogel with coral-like supramolecular structure from 1,4-dioxane. The cooperation of hydrogen bonding and the hydrophobic diversity between these components are the main contributions to the specific superstructure. The two-component gel exhibits reversible photoisomerization from trans to cis transition without breakage of the gel state.

  10. Stripes and honeycomb lattice of quantized vortices in rotating two-component Bose-Einstein condensates

    Science.gov (United States)

    Kasamatsu, Kenichi; Sakashita, Kouhei

    2018-05-01

    We study numerically the structure of a vortex lattice in rotating two-component Bose-Einstein condensates with equal atomic masses and equal intra- and intercomponent coupling strengths. The numerical simulations of the Gross-Pitaevskii equation show that the quantized vortices in this situation form lattice configuration accompanying vortex stripes, honeycomb lattices, and their complexes. This is a result of the degeneracy of the system for the SU(2) symmetric operation, which causes a continuous transformation between the above structures. In terms of the pseudospin representation, the complex lattice structures are identified as a hexagonal lattice of doubly winding half skyrmions.

  11. Laser doppler perfusion imaging

    International Nuclear Information System (INIS)

    Waardell, K.

    1992-01-01

    Recording of tissue perfusion is important in assessing the influence of peripheral vascular diseases on the microcirculation. This thesis reports on a laser doppler perfusion imager based on dynamic light scattering in tissue. When a low power He-Ne laser beam sequentally scans the tissue, moving blood cells generate doppler components in the back-scattered light. A fraction of this light is detected by a photodetector and converted into an electrical signal. In the processor, a signal proportional to the tissue perfusion at each measurement site is calculated and stored. When the scanning procedure is completed, a color-coded perfusion image is presented on a monitor. To convert important aspects of the perfusion image into more quantitative parameters, data analysis functions are implemented in the software. A theory describing the dependence of the distance between individual measurement points and detector on the system amplification factor is proposed and correction algorithms are presented. The performance of the laser doppler perfusion imager was evaluated using a flow simulator. A linear relationship between processor output signal and flow through the simulator was demonstrated for blood cell concentrations below 0.2%. The median sampling depth of the laser beam was simulated by a Monte Carlo technique and estimated to 235 μm. The perfusion imager has been used in the clinic to study perfusion changes in port wine stains treated with argon laser and to investigate the intensity and extension of the cutaneous axon reflex response after electrical nerve stimulation. The fact that perfusion can be visualized without touching the tissue implies elimination of sterilization problems, thus simplifying clinical investigations of perfusion in association with diagnosis and treatment of peripheral vascular diseases. 22 refs

  12. Two-Component Signal Transduction System SaeRS Positively Regulates Staphylococcus epidermidis Glucose Metabolism

    Directory of Open Access Journals (Sweden)

    Qiang Lou

    2014-01-01

    Full Text Available Staphylococcus epidermidis, which is a causative pathogen of nosocomial infection, expresses its virulent traits such as biofilm and autolysis regulated by two-component signal transduction system SaeRS. In this study, we performed a proteomic analysis of differences in expression between the S. epidermidis 1457 wild-type and saeRS mutant to identify candidates regulated by saeRS using two-dimensional gel electrophoresis (2-DE combined with matrix-assisted laser desorption/lonization mass spectrometry (MALDI-TOF-MS. Of 55 identified proteins that significantly differed in expression between the two strains, 15 were upregulated and 40 were downregulated. The downregulated proteins included enzymes related to glycolysis and TCA cycle, suggesting that glucose is not properly utilized in S. epidermidis when saeRS was deleted. The study will be helpful for treatment of S. epidermidis infection from the viewpoint of metabolic modulation dependent on two-component signal transduction system SaeRS.

  13. Rotation and toroidal magnetic field effects on the stability of two-component jets

    Science.gov (United States)

    Millas, Dimitrios; Keppens, Rony; Meliani, Zakaria

    2017-09-01

    Several observations of astrophysical jets show evidence of a structure in the direction perpendicular to the jet axis, leading to the development of 'spine and sheath' models of jets. Most studies focus on a two-component jet consisting of a highly relativistic inner jet and a slower - but still relativistic - outer jet surrounded by an unmagnetized environment. These jets are believed to be susceptible to a relativistic Rayleigh-Taylor-type instability, depending on the effective inertia ratio of the two components. We extend previous studies by taking into account the presence of a non-zero toroidal magnetic field. Different values of magnetization are examined to detect possible differences in the evolution and stability of the jet. We find that the toroidal field, above a certain level of magnetization σ, roughly equal to 0.01, can stabilize the jet against the previously mentioned instabilities and that there is a clear trend in the behaviour of the average Lorentz factor and the effective radius of the jet when we continuously increase the magnetization. The simulations are performed using the relativistic MHD module from the open source, parallel, grid adaptive, mpi-amrvac code.

  14. Analytical energy gradient for the two-component normalized elimination of the small component method

    Energy Technology Data Exchange (ETDEWEB)

    Zou, Wenli; Filatov, Michael; Cremer, Dieter, E-mail: dcremer@smu.edu [Computational and Theoretical Chemistry Group (CATCO), Department of Chemistry, Southern Methodist University, 3215 Daniel Ave, Dallas, Texas 75275-0314 (United States)

    2015-06-07

    The analytical gradient for the two-component Normalized Elimination of the Small Component (2c-NESC) method is presented. The 2c-NESC is a Dirac-exact method that employs the exact two-component one-electron Hamiltonian and thus leads to exact Dirac spin-orbit (SO) splittings for one-electron atoms. For many-electron atoms and molecules, the effect of the two-electron SO interaction is modeled by a screened nucleus potential using effective nuclear charges as proposed by Boettger [Phys. Rev. B 62, 7809 (2000)]. The effect of spin-orbit coupling (SOC) on molecular geometries is analyzed utilizing the properties of the frontier orbitals and calculated SO couplings. It is shown that bond lengths can either be lengthened or shortened under the impact of SOC where in the first case the influence of low lying excited states with occupied antibonding orbitals plays a role and in the second case the jj-coupling between occupied antibonding and unoccupied bonding orbitals dominates. In general, the effect of SOC on bond lengths is relatively small (≤5% of the scalar relativistic changes in the bond length). However, large effects are found for van der Waals complexes Hg{sub 2} and Cn{sub 2}, which are due to the admixture of more bonding character to the highest occupied spinors.

  15. Analytical energy gradient for the two-component normalized elimination of the small component method

    Science.gov (United States)

    Zou, Wenli; Filatov, Michael; Cremer, Dieter

    2015-06-01

    The analytical gradient for the two-component Normalized Elimination of the Small Component (2c-NESC) method is presented. The 2c-NESC is a Dirac-exact method that employs the exact two-component one-electron Hamiltonian and thus leads to exact Dirac spin-orbit (SO) splittings for one-electron atoms. For many-electron atoms and molecules, the effect of the two-electron SO interaction is modeled by a screened nucleus potential using effective nuclear charges as proposed by Boettger [Phys. Rev. B 62, 7809 (2000)]. The effect of spin-orbit coupling (SOC) on molecular geometries is analyzed utilizing the properties of the frontier orbitals and calculated SO couplings. It is shown that bond lengths can either be lengthened or shortened under the impact of SOC where in the first case the influence of low lying excited states with occupied antibonding orbitals plays a role and in the second case the jj-coupling between occupied antibonding and unoccupied bonding orbitals dominates. In general, the effect of SOC on bond lengths is relatively small (≤5% of the scalar relativistic changes in the bond length). However, large effects are found for van der Waals complexes Hg2 and Cn2, which are due to the admixture of more bonding character to the highest occupied spinors.

  16. Two component WIMP-FImP dark matter model with singlet fermion, scalar and pseudo scalar

    Energy Technology Data Exchange (ETDEWEB)

    Dutta Banik, Amit; Pandey, Madhurima; Majumdar, Debasish [Saha Institute of Nuclear Physics, HBNI, Astroparticle Physics and Cosmology Division, Kolkata (India); Biswas, Anirban [Harish Chandra Research Institute, Allahabad (India)

    2017-10-15

    We explore a two component dark matter model with a fermion and a scalar. In this scenario the Standard Model (SM) is extended by a fermion, a scalar and an additional pseudo scalar. The fermionic component is assumed to have a global U(1){sub DM} and interacts with the pseudo scalar via Yukawa interaction while a Z{sub 2} symmetry is imposed on the other component - the scalar. These ensure the stability of both dark matter components. Although the Lagrangian of the present model is CP conserving, the CP symmetry breaks spontaneously when the pseudo scalar acquires a vacuum expectation value (VEV). The scalar component of the dark matter in the present model also develops a VEV on spontaneous breaking of the Z{sub 2} symmetry. Thus the various interactions of the dark sector and the SM sector occur through the mixing of the SM like Higgs boson, the pseudo scalar Higgs like boson and the singlet scalar boson. We show that the observed gamma ray excess from the Galactic Centre as well as the 3.55 keV X-ray line from Perseus, Andromeda etc. can be simultaneously explained in the present two component dark matter model and the dark matter self interaction is found to be an order of magnitude smaller than the upper limit estimated from the observational results. (orig.)

  17. Two-component vector solitons in defocusing Kerr-type media with spatially modulated nonlinearity

    Energy Technology Data Exchange (ETDEWEB)

    Zhong, Wei-Ping, E-mail: zhongwp6@126.com [Department of Electronic and Information Engineering, Shunde Polytechnic, Guangdong Province, Shunde 528300 (China); Texas A and M University at Qatar, P.O. Box 23874 Doha (Qatar); Belić, Milivoj [Texas A and M University at Qatar, P.O. Box 23874 Doha (Qatar); Institute of Physics, University of Belgrade, P.O. Box 57, 11001 Belgrade (Serbia)

    2014-12-15

    We present a class of exact solutions to the coupled (2+1)-dimensional nonlinear Schrödinger equation with spatially modulated nonlinearity and a special external potential, which describe the evolution of two-component vector solitons in defocusing Kerr-type media. We find a robust soliton solution, constructed with the help of Whittaker functions. For specific choices of the topological charge, the radial mode number and the modulation depth, the solitons may exist in various forms, such as the half-moon, necklace-ring, and sawtooth vortex-ring patterns. Our results show that the profile of such solitons can be effectively controlled by the topological charge, the radial mode number, and the modulation depth. - Highlights: • Two-component vector soliton clusters in defocusing Kerr-type media are reported. • These soliton clusters are constructed with the help of Whittaker functions. • The half-moon, necklace-ring and vortex-ring patterns are found. • The profile of these solitons can be effectively controlled by three soliton parameters.

  18. Patient Autonomy for the Management of Chronic Conditions: A Two-Component Re-conceptualization

    Science.gov (United States)

    Naik, Aanand D.; Dyer, Carmel B.; Kunik, Mark E.; McCullough, Laurence B.

    2010-01-01

    The clinical application of the concept of patient autonomy has centered on the ability to deliberate and make treatment decisions (decisional autonomy) to the virtual exclusion of the capacity to execute the treatment plan (executive autonomy). However, the one-component concept of autonomy is problematic in the context of multiple chronic conditions. Adherence to complex treatments commonly breaks down when patients have functional, educational, and cognitive barriers that impair their capacity to plan, sequence, and carry out tasks associated with chronic care. The purpose of this article is to call for a two-component re-conceptualization of autonomy and to argue that the clinical assessment of capacity for patients with chronic conditions should be expanded to include both autonomous decision making and autonomous execution of the agreed-upon treatment plan. We explain how the concept of autonomy should be expanded to include both decisional and executive autonomy, describe the biopsychosocial correlates of the two-component concept of autonomy, and recommend diagnostic and treatment strategies to support patients with deficits in executive autonomy. PMID:19180389

  19. Shape-persistent two-component 2D networks with atomic-size tunability.

    Science.gov (United States)

    Liu, Jia; Zhang, Xu; Wang, Dong; Wang, Jie-Yu; Pei, Jian; Stang, Peter J; Wan, Li-Jun

    2011-09-05

    Over the past few years, two-dimensional (2D) nanoporous networks have attracted great interest as templates for the precise localization and confinement of guest building blocks, such as functional molecules or clusters on the solid surfaces. Herein, a series of two-component molecular networks with a 3-fold symmetry are constructed on graphite using a truxenone derivative and trimesic acid homologues with carboxylic-acid-terminated alkyl chains. The hydrogen-bonding partner-recognition-induced 2D crystallization of alkyl chains makes the flexible alkyl chains act as rigid spacers in the networks to continuously tune the pore size with an accuracy of one carbon atom per step. The two-component networks were found to accommodate and regulate the distribution and aggregation of guest molecules, such as COR and CuPc. This procedure provides a new pathway for the design and fabrication of molecular nanostructures on solid surfaces. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Method of estimating changes in vapor concentrations continuously generated from two-component organic solvents.

    Science.gov (United States)

    Hori, Hajime; Ishidao, Toru; Ishimatsu, Sumiyo

    2010-12-01

    We measured vapor concentrations continuously evaporated from two-component organic solvents in a reservoir and proposed a method to estimate and predict the evaporation rate or generated vapor concentrations. Two kinds of organic solvents were put into a small reservoir made of glass (3 cm in diameter and 3 cm high) that was installed in a cylindrical glass vessel (10 cm in diameter and 15 cm high). Air was introduced into the glass vessel at a flow rate of 150 ml/min, and the generated vapor concentrations were intermittently monitored for up to 5 hours with a gas chromatograph equipped with a flame ionization detector. The solvent systems tested in this study were the methanoltoluene system and the ethyl acetate-toluene system. The vapor concentrations of the more volatile component, that is, methanol in the methanol-toluene system and ethyl acetate in the ethyl acetate-toluene system, were high at first, and then decreased with time. On the other hand, the concentrations of the less volatile component were low at first, and then increased with time. A model for estimating multicomponent organic vapor concentrations was developed, based on a theory of vapor-liquid equilibria and a theory of the mass transfer rate, and estimated values were compared with experimental ones. The estimated vapor concentrations were in relatively good agreement with the experimental ones. The results suggest that changes in concentrations of two-component organic vapors continuously evaporating from a liquid reservoir can be estimated by the proposed model.

  1. Determination of two-dimensional correlation lengths in an anisotropic two-component flow

    International Nuclear Information System (INIS)

    Thomson, O.

    1994-05-01

    Former studies have shown that correlation methods can be used for determination of various two-component flow parameters, among these the correlation length. In cases where the flow can be described as a mixture, in which the minority component forms spatially limited perturbations within the majority component, this parameter gives a good indication of the maximum extension of these perturbations. In the former studies, spherical symmetry of the perturbations has been assumed, and the correlation length has been measured in the direction of the flow (axially) only. However, if the flow structure is anisotropic, the correlation length will be different in different directions. In the present study, the method has been developed further, allowing also measurements perpendicular to the flow direction (radially). The measurements were carried out using laser beams and the two-component flows consisted of either glass beads and air or air and water. In order to make local measurements of both the axial and radial correlation length simultaneously, it is necessary to use 3 laser beams and to form the triple cross-covariance. This lead to some unforeseen complications, due to the character of this function. The experimental results are generally positive and size determinations with an accuracy of better than 10% have been achieved in most cases. Less accurate results appeared only for difficult conditions (symmetrical signals), when 3 beams were used. 5 refs, 13 figs, 3 tabs

  2. Regularity for 3D Navier-Stokes equations in terms of two components of the vorticity

    Directory of Open Access Journals (Sweden)

    Sadek Gala

    2010-10-01

    Full Text Available We establish regularity conditions for the 3D Navier-Stokes equation via two components of the vorticity vector. It is known that if a Leray-Hopf weak solution $u$ satisfies $$ ilde{omega}in L^{2/(2-r}(0,T;L^{3/r}(mathbb{R}^3quad hbox{with }0two components of the vorticity, $omega =operatorname{curl}u$, then $u$ becomes the classical solution on $(0,T]$ (see [5]. We prove the regularity of Leray-Hopf weak solution $u$ under each of the following two (weaker conditions: $$displaylines{ ilde{omega}in L^{2/(2-r}(0,T;dot {mathcal{M}}_{2, 3/r}(mathbb{R}^3quad hbox{for }0

  3. Principles of doppler tomography

    International Nuclear Information System (INIS)

    Juhlin, P.

    1992-08-01

    This paper shows how the radon transform can be used to determine vector fields. A scheme to determine the velocity field of a moving fluid by measurements with a continuous doppler signal is suggested. When the flow is confined to a bounded domain, as is the case in most applications, it can be uniquely decomposed into one gradiental and one rotational part. The former vanishes if the fluid is incompressible and source-free, and the latter can be completely reconstructed by the methods proposed in this paper if the domain is simply connected. Special attention is paid to laminar flow in a long cylindrical vessel with circular cross-section. Under such conditions the flow profile becomes parabolic, which makes the vessel recognizable as a typical 'N-shaped' pattern in an image describing the rotation of the velocity field. The vessel yields the same doppler tomographic pattern, no matter how it is sectioned. The ideas presented should be applicable also when studying the flow in blood vessels, even if the flow profile in these is not quite parabolic. The discrepancies only make the 'N-shape' somewhat distorted

  4. Comparisons between PW Doppler system and enhanced FM Doppler system

    DEFF Research Database (Denmark)

    Wilhjelm, Jens E.; Pedersen, P. C.

    1995-01-01

    This paper presents a new implementation of an echo-ranging FM Doppler system with improved performance, relative to the FM Doppler system reported previously. The use of long sweeps provides a significant reduction in peak to average power ratio compared to pulsed wave (PW) emission. A PW Doppler...... system exploits the direct relationship between arrival time of the received signal and range from the transducer. In the FM Doppler systems, a similar relationship exists in the spectral domain of the demodulated received signals, so that range is represented by frequency. Thus, a shift in location...... of moving scatterers between consecutive emissions corresponds to a frequency shift in the spectral signature. The improvement relative to the earlier version of the FM Doppler system is attained by utilizing cross-correlation of real spectra rather than of magnitude spectra for assessing flow velocity...

  5. A Principle of Corresponding States for Two-Component, Self-Gravitating Fluids

    Directory of Open Access Journals (Sweden)

    Caimmi, R.

    2010-06-01

    Full Text Available Macrogases are defined as two-component,large-scale celestial objects where the subsystems interact only via gravitation.The macrogas equation of state is formulated and compared to the van der Waals (VDWequation of state for ordinary gases.By analogy, it is assumed that real macroisothermal curves in macrogases occur as real isothermal curves in ordinary gases, where a phase transition(vapour-liquid observed in ordinary gases and gas-stars assumed in macrogases takesplace along a horizontal linein the macrovolume-macropressure{small $({sf O}sX_mathrm{V}sX_mathrm{p}$} plane.The intersections between real and theoretical(deduced from the equation of state macro isothermalcurves, make two regions of equal surface as for ordinary gases obeying the VDW equation of state.A numerical algorithm is developed for determining the following points of a selected theoretical macroisothermal curve on the {small $({sf O}sX_mathrm{V}sX_mathrm{p}$} plane:the three intersections with the related real macroisothermal curve,and the two extremum points (one maximum and one minimum. Different kinds of macrogases are studied in detail: UU, where U density profiles are flat, to be conceived as a simple guidance case; HH, where H density profiles obey the Hernquist (1990 law, which satisfactorily fits the observed spheroidal components of galaxies; HN/NH, where N density profiles obey the Navarro-Frenk-White (1995,1996, 1997 law, which satisfactorily fits the simulated nonbaryonic dark matter haloes.A different trend is shown by theoretical macroisothermal curves on the{small $({sf O}sX_mathrm{V}sX_mathrm{p}$} plane,according to whether density profiles are sufficiently mild (UU or sufficiently steep (HH, HN/NH.In the former alternative, no critical macroisothermal curve exists, below or above which the trend is monotonous. In the latter alternative, a critical macroisothermal curve exists, as shown by VDW gases, where the critical point may be defined as the horizontal

  6. A principle of corresponding states for two-component, self-gravitating fluids

    Directory of Open Access Journals (Sweden)

    Caimmi R.

    2010-01-01

    Full Text Available Macrogases are defined as two-component, large-scale celestial objects where the subsystems interact only via gravitation. The macrogas equation of state is formulated and compared to the van der Waals (VDW equation of state for ordinary gases. By analogy, it is assumed that real macroisothermal curves in macrogases occur as real isothermal curves in ordinary gases, where a phase transition (vapour-liquid observed in ordinary gases and gas-stars assumed in macrogases takes place along a horizontal line in the macrovolume-macropressure (O, Xv, Xp plane. The intersections between real and theoretical (deduced from the equation of state macroisothermal curves, make two regions of equal surface as for ordinary gases obeying the VDW equation of state. A numerical algorithm is developed for determining the following points of a selected theoretical macroisothermal curve on the (O, Xv, Xp plane: the three intersections with the related real macroisothermal curve, and the two extremum points (one maximum and one minimum. Different kinds of macrogases are studied in detail: UU, where U density profiles are flat, to be conceived as a simple guidance case; HH, where H density profiles obey the Hernquist (1990 law, which satisfactorily fits the observed spheroidal components of galaxies; HN/NH, where N density profiles obey the Navarro-Frenk-White (1995, 1996, 1997 law, which satisfactorily fits the simulated nonbaryonic dark matter haloes. A different trend is shown by theoretical macroisothermal curves on the (O/XV/Xp plane, according to whether density profiles are sufficiently mild (UU or sufficiently steep (HH, HN/NH. In the former alternative, no critical macroisothermal curve exists, below or above which the trend is monotonous. In the latter alternative, a critical macroisothermal curve exists, as shown by VDW gases, where the critical point may be defined as the horizontal inflexion point. In any case, by analogy with VDW gases, the first quadrant

  7. Linearmycins Activate a Two-Component Signaling System Involved in Bacterial Competition and Biofilm Morphology

    Science.gov (United States)

    2017-01-01

    ABSTRACT Bacteria use two-component signaling systems to adapt and respond to their competitors and changing environments. For instance, competitor bacteria may produce antibiotics and other bioactive metabolites and sequester nutrients. To survive, some species of bacteria escape competition through antibiotic production, biofilm formation, or motility. Specialized metabolite production and biofilm formation are relatively well understood for bacterial species in isolation. How bacteria control these functions when competitors are present is not well studied. To address fundamental questions relating to the competitive mechanisms of different species, we have developed a model system using two species of soil bacteria, Bacillus subtilis and Streptomyces sp. strain Mg1. Using this model, we previously found that linearmycins produced by Streptomyces sp. strain Mg1 cause lysis of B. subtilis cells and degradation of colony matrix. We identified strains of B. subtilis with mutations in the two-component signaling system yfiJK operon that confer dual phenotypes of specific linearmycin resistance and biofilm morphology. We determined that expression of the ATP-binding cassette (ABC) transporter yfiLMN operon, particularly yfiM and yfiN, is necessary for biofilm morphology. Using transposon mutagenesis, we identified genes that are required for YfiLMN-mediated biofilm morphology, including several chaperones. Using transcriptional fusions, we found that YfiJ signaling is activated by linearmycins and other polyene metabolites. Finally, using a truncated YfiJ, we show that YfiJ requires its transmembrane domain to activate downstream signaling. Taken together, these results suggest coordinated dual antibiotic resistance and biofilm morphology by a single multifunctional ABC transporter promotes competitive fitness of B. subtilis. IMPORTANCE DNA sequencing approaches have revealed hitherto unexplored diversity of bacterial species in a wide variety of environments that

  8. A study of doppler waveform using pulsatile flow model

    International Nuclear Information System (INIS)

    Chung, Hye Won; Chung, Myung Jin; Park, Jae Hyung; Chung, Jin Wook; Lee, Dong Hyuk; Min, Byoung Goo

    1997-01-01

    Through the construction of a pulsatile flow model using an artificial heart pump and stenosis to demonstrate triphasic Doppler waveform, which simulates in vivo conditions, and to evaluate the relationship between Doppler waveform and vascular compliance. The flow model was constructed using a flowmeter, rubber tube, glass tube with stenosis, and artificial heart pump. Doppler study was carried out at the prestenotic, poststenotic, and distal segments;compliance was changed by changing the length of the rubber tube. With increasing proximal compliance, Doppler waveforms show decreasing peak velocity of the first phase and slightly delayed acceleration time, but the waveform itself did not change significantly. Distal compliance influenced the second phase, and was important for the formation of pulsus tardus and parvus, which without poststenotic vascular compliance, did not develop. The peak velocity of the first phase was inversely proportional to proximal compliance, and those of the second and third phases were directly proportional to distal compliance. After constructing this pulsatile flow model, we were able to explain the relationship between vascular compliance and Doppler waveform, and also better understand the formation of pulsus tardus and parvus

  9. [Regulation of sporulation by two-component system YvcPQ in Bacillus thuringiensis].

    Science.gov (United States)

    Fan, Qingyun; Zhang, Shumeng; Gong, Yujing; He, Jin

    2017-01-04

    To study the regulation of sporulation controlled by two-component system (TCS) YvcPQ. β-galactosidase experiment was used to verify the regulation of YvcP on kapD expression; bacterial one-hybrid assay, EMSA and RT-qPCR were applied to study the regulation of AbrB on yvcPQ expression; markerless gene deletion coupled with spore count was used to reveal the influence of yvcPQ and kapD expressions on sporulation. transcriptional regulator AbrB up-regulated the expression of yvcPQ; YvcP promoted the expression of kapD to inhibit sporulation. AbrB up-regulated the transcription of yvcPQ operon, then the increased YvcP strengthened the transcriptional acitivation of sporulation inhibitor gene kapD, and subsequently inhibited sporulation.

  10. Universal Properties of a Trapped Two-Component Fermi Gas at Unitarity

    International Nuclear Information System (INIS)

    Blume, D.; Stecher, J. von; Greene, Chris H.

    2007-01-01

    We treat the trapped two-component Fermi system, in which unlike fermions interact through a two-body short-range potential having no bound state but an infinite scattering length. By accurately solving the Schroedinger equation for up to N=6 fermions, we show that no many-body bound states exist other than those bound by the trapping potential, and we demonstrate unique universal properties of the system: Certain excitation frequencies are separated by 2(ℎ/2π)ω, the wave functions agree with analytical predictions and a virial theorem is fulfilled. Further calculations up to N=30 determine the excitation gap, an experimentally accessible universal quantity, and it agrees with recent predictions based on a density functional approach

  11. TWO-COMPONENT SYSTEM: A MOLECULAR DIALOGUE BETWEEN RUMINAL BACTERIA AND FEED PARTICLES (FORAGE PLANTS

    Directory of Open Access Journals (Sweden)

    Monica Marcela Galicia Jimenez

    2017-12-01

    Full Text Available The ability to adapt rapidly to changes in the environment is one of the main characteristics of the bacterial cell. The rumen is a highly dynamic environment, and none of the changes are permanent due to the various microbial species found in the rumen. Signal transduction networks are information processing pathways that recognize various physical and chemical stimuli, amplification, signal processing, and trigger responses of the bacterial cell. The aim of the present review is to show the importance of these two component systems in rumen bacteria, because it is based on the knowledge of the principles governing the bacterial population communication, its main interactions and products of metabolism, we can approach the manipulation of Ruminal fermentation to improve animal health, productivity and food safety.

  12. Phosphate sink containing two-component signaling systems as tunable threshold devices

    DEFF Research Database (Denmark)

    Amin, Munia; Kothamachu, Varun B; Feliu, Elisenda

    2014-01-01

    Synthetic biology aims to design de novo biological systems and reengineer existing ones. These efforts have mostly focused on transcriptional circuits, with reengineering of signaling circuits hampered by limited understanding of their systems dynamics and experimental challenges. Bacterial two......-component signaling systems offer a rich diversity of sensory systems that are built around a core phosphotransfer reaction between histidine kinases and their output response regulator proteins, and thus are a good target for reengineering through synthetic biology. Here, we explore the signal-response relationship...... rapid signal termination, whereby one of the RRs acts as a phosphate sink towards the other RR (i.e. the output RR), but also implements a sigmoidal signal-response relationship. We identify two mathematical conditions on system parameters that are necessary for sigmoidal signal-response relationships...

  13. Characterization of a two-component thermoluminescent albedo dosemeter according to ISO 21909

    Energy Technology Data Exchange (ETDEWEB)

    Martins, M.M., E-mail: marcelo@ird.gov.b [Instituto de Radioprotecao e Dosimetria (IRD/CNEN), Av. Salvador Allende s/n, CEP 22780-160, Rio de Janeiro, RJ (Brazil); Mauricio, C.L.P., E-mail: claudia@ird.gov.b [Instituto de Radioprotecao e Dosimetria (IRD/CNEN), Av. Salvador Allende s/n, CEP 22780-160, Rio de Janeiro, RJ (Brazil); Pereira, W.W., E-mail: walsan@ird.gov.b [Instituto de Radioprotecao e Dosimetria (IRD/CNEN), Av. Salvador Allende s/n, CEP 22780-160, Rio de Janeiro, RJ (Brazil); Silva, A.X. da, E-mail: ademir@con.ufrj.b [Coordenacao dos Programas de Pos-Graduacao em Engenharia, COPPE/PEN Caixa Postal 68509, CEP 21941-972, Rio de Janeiro, RJ (Brazil)

    2011-05-15

    A two-component thermoluminescent albedo neutron monitoring system was developed at Instituto de Radioprotecao e Dosimetria, Brazil. As there is no Brazilian regulation for neutron individual monitoring service, the system was tested according to the ISO 21909 standard. This standard provides performance and test requirements for determining the acceptability of personal neutron dosemeters to be used for the measurement of personal dose equivalent, H{sub p}(10), in neutron fields with energies ranging from thermal to 20 MeV. Up to 40 dosemeters were used in order to accomplish satisfactorily the requirements of some tests. Despite operational difficulties, this albedo system passed all ISO 21909 performance requirements. The results and problems throughout this characterization are discussed in this paper.

  14. Modulational instability for a self-attractive two-component Bose–Einstein condensate

    International Nuclear Information System (INIS)

    Sheng-Chang, Li; Wen-Shan, Duan

    2009-01-01

    By means of the multiple-scale expansion method, the coupled nonlinear Schrödinger equations without an explicit external potential are obtained in two-dimensional geometry for a self-attractive Bose–Einstein condensate composed of different hyperfine states. The modulational instability of two-component condensate is investigated by using a simple technique. Based on the discussion about two typical cases, the explicit expression of the growth rate for a purely growing modulational instability and the optimum stable conditions are given and analysed analytically. The results show that the modulational instability of this two-dimensional system is quite different from that in a one-dimensional system. (general)

  15. A two-component system regulates hemin acquisition in Porphyromonas gingivalis.

    Directory of Open Access Journals (Sweden)

    Jodie C Scott

    Full Text Available Porphyromonas gingivalis is a Gram-negative oral anaerobe associated with infection of the periodontia. The organism has a small number of two-component signal transduction systems, and after comparing genome sequences of strains W83 and ATCC 33277 we discovered that the latter was mutant in histidine kinase (PGN_0752, while the cognate response regulator (PGN_0753 remained intact. Microarray-based transcriptional profiling and ChIP-seq assays were carried out with an ATCC 33277 transconjugant containing the functional histidine kinase from strain W83 (PG0719. The data showed that the regulon of this signal transduction system contained genes that were involved in hemin acquisition, including gingipains, at least three transport systems, as well as being self-regulated. Direct regulation by the response regulator was confirmed by electrophoretic mobility shift assays. In addition, the system appears to be activated by hemin and the regulator acts as both an activator and repressor.

  16. Two-component air heating system. Final report. Zweikomponenten-Luftheizungs-System. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Radtke, W; Thiel, D

    1986-01-01

    The two-component heating system consists of a combination of air-based floor heating and direct air heating, with ventilation and extraction and heat recovery. The direct airflow consists exclusively of heated outside air, the amount corresponding to the building's external air intake requirement. The control system comprises a two-step sequential control of the air throughput of the direct air heating system and of the air distribution for the floor heating airflow. A special heating switch makes it possible to switch off the direct air heating system separately, and to select rapid warm-up. The way in which the new heating system works has been tested in a pilot set-up and proven by comprehensive measurements. In addition, a simulation model was produced which gave substantial confirmation of the measurements. (orig.) With 9 refs., 37 tabs., 63 figs.

  17. Plasma oscillations and sound waves in collision-dominated two-component plasmas

    International Nuclear Information System (INIS)

    Hansen, J.P.; Sjoegren, L.

    1982-01-01

    Charge, mass, and electron density fluctuation spectra of strongly correlated, fully ionized two-component plasmas within the framework of the Mori--Zwanzig memory function formalism are analyzed. All dynamical correlation functions are expressed in terms of the memory functions of the ion and electron velocity autocorrelation functions by a generalized effective field approximation which preserves the exact initial values (i.e., static correlations). The theory reduces correctly to the mean field (or collisionless Vlasov) results in the weak coupling limit, and yields charge density fluctuation spectra in good agreement with available computer simulation data, as well as reasonable estimates of the transport coefficients. The collisional damping and frequency shift of the plasma oscillation mode are sizeable, even in the long wavelength limit. The theory also predicts the propagation of well-defined sound waves in dense plasmas in thermal equilibrium

  18. A two component model describing nucleon structure functions in the low-x region

    Energy Technology Data Exchange (ETDEWEB)

    Bugaev, E.V. [Institute for Nuclear Research of the Russian Academy of Sciences, 7a, 60th October Anniversary prospect, Moscow 117312 (Russian Federation); Mangazeev, B.V. [Irkutsk State University, 1, Karl Marx Street, Irkutsk 664003 (Russian Federation)

    2009-12-15

    A two component model describing the electromagnetic nucleon structure functions in the low-x region, based on generalized vector dominance and color dipole approaches is briefly described. The model operates with the mesons of rho-family having the mass spectrum of the form m{sub n}{sup 2}=m{sub r}ho{sup 2}(1+2n) and takes into account the nondiagonal transitions in meson-nucleon scattering. The special cut-off factors are introduced in the model, to exclude the gamma-qq-bar-V transitions in the case of narrow qq-bar-pairs. For the color dipole part of the model the well known FKS-parameterization is used.

  19. Two-component mixture model: Application to palm oil and exchange rate

    Science.gov (United States)

    Phoong, Seuk-Yen; Ismail, Mohd Tahir; Hamzah, Firdaus Mohamad

    2014-12-01

    Palm oil is a seed crop which is widely adopt for food and non-food products such as cookie, vegetable oil, cosmetics, household products and others. Palm oil is majority growth in Malaysia and Indonesia. However, the demand for palm oil is getting growth and rapidly running out over the years. This phenomenal cause illegal logging of trees and destroy the natural habitat. Hence, the present paper investigates the relationship between exchange rate and palm oil price in Malaysia by using Maximum Likelihood Estimation via Newton-Raphson algorithm to fit a two components mixture model. Besides, this paper proposes a mixture of normal distribution to accommodate with asymmetry characteristics and platykurtic time series data.

  20. Level shift two-components autoregressive conditional heteroscedasticity modelling for WTI crude oil market

    Science.gov (United States)

    Sin, Kuek Jia; Cheong, Chin Wen; Hooi, Tan Siow

    2017-04-01

    This study aims to investigate the crude oil volatility using a two components autoregressive conditional heteroscedasticity (ARCH) model with the inclusion of abrupt jump feature. The model is able to capture abrupt jumps, news impact, clustering volatility, long persistence volatility and heavy-tailed distributed error which are commonly observed in the crude oil time series. For the empirical study, we have selected the WTI crude oil index from year 2000 to 2016. The results found that by including the multiple-abrupt jumps in ARCH model, there are significant improvements of estimation evaluations as compared with the standard ARCH models. The outcomes of this study can provide useful information for risk management and portfolio analysis in the crude oil markets.

  1. Functional assessment of EnvZ/OmpR two-component system in Shewanella oneidensis.

    Directory of Open Access Journals (Sweden)

    Jie Yuan

    Full Text Available EnvZ and OmpR constitute the bacterial two-component signal transduction system known to mediate osmotic stress response in a number of gram-negative bacteria. In an effort to understand the mechanism through which Shewanella oneidensis senses and responds to environmental osmolarity changes, structure of the ompR-envZ operon was determined with Northern blotting assay and roles of the EnvZ/OmpR two-component system in response to various stresses were investigated with mutational analysis, quantitative reverse transcriptase PCR (qRT-PCR, and phenotype microarrays. Results from the mutational analysis and qRT-PCR suggested that the EnvZ/OmpR system contributed to osmotic stress response of S. oneidensis and very likely engaged a similar strategy employed by E. coli, which involved reciprocal regulation of two major porin coding genes. Additionally, the ompR-envZ system was also found related to cell motility. We further showed that the ompR-envZ dependent regulation of porin genes and motility resided almost completely on ompR and only partially on envZ, indicating additional mechanisms for OmpR phosphorylation. In contrast to E. coli lacking ompR-envZ, however, growth of S. oneidensis did not show a significant dependence on ompR-envZ even under osmotic stress. Further analysis with phenotype microarrays revealed that the S. oneidensis strains lacking a complete ompR-envZ system displayed hypersensitivities to a number of agents, especially in alkaline environment. Taken together, our results suggest that the function of the ompR-envZ system in S. oneidensis, although still connected with osmoregulation, has diverged considerably from that of E. coli. Additional mechanism must exist to support growth of S. oneidensis under osmotic stress.

  2. Regulation of virulence by a two-component system in group B streptococcus.

    Science.gov (United States)

    Jiang, Sheng-Mei; Cieslewicz, Michael J; Kasper, Dennis L; Wessels, Michael R

    2005-02-01

    Group B Streptococcus (GBS) is frequently carried in the gastrointestinal or genitourinary tract as a commensal organism, yet it has the potential to cause life-threatening infection in newborn infants, pregnant women, and individuals with chronic illness. Regulation of virulence factor expression may affect whether GBS behaves as an asymptomatic colonizer or an invasive pathogen, but little is known about how such factors are controlled in GBS. We now report the characterization of a GBS locus that encodes a two-component regulatory system similar to CsrRS (or CovRS) in Streptococcus pyogenes. Inactivation of csrR, encoding the putative response regulator, in two unrelated wild-type strains of GBS resulted in a marked increase in production of beta-hemolysin/cytolysin and a striking decrease in production of CAMP factor, an unrelated cytolytic toxin. Quantitative RNA hybridization experiments revealed that these two phenotypes were associated with a marked increase and decrease in expression of the corresponding genes, cylE and cfb, respectively. The CsrR mutant strains also displayed increased expression of scpB encoding C5a peptidase. Similar, but less marked, changes in gene expression were observed in CsrS (putative sensor component) mutants, evidence that CsrR and CsrS constitute a functional two-component system. Experimental infection studies in mice demonstrated reduced virulence of both CsrR and CsrS mutant strains relative to the wild type. Together, these results indicate that CsrRS regulates expression of multiple GBS virulence determinants and is likely to play an important role in GBS pathogenesis.

  3. Nonlinear light scattering in a two component medium: optical limiting application

    International Nuclear Information System (INIS)

    Joudrier, Valerie

    1998-01-01

    Scattering is a fundamental manifestation of the interaction between matter and radiation, resulting from inhomogeneities in the refractive index, which decrease transmission. This phenomenon is then especially attractive for sensor protection from laser light by optical limiting. One of the methods to induce scattering at high incident energy is to make use of the Kerr effect where the index of refraction is intensity dependent. Thus, the idea is to use a two component medium with a good index matching between the two components at low intensity, resulting in the medium transparency, and to modify it, at high intensity, due to the non linearity of one component making the medium highly scattering. Some of the experimental and theoretical investigations concerning a new material (here, a cell containing some liquid with small silica particles as inclusion in it) are presented in the visible domain (I=532 nm), for the nanosecond protection regime, beginning, with the chemical synthesis of the sample. The experimental results concerning the optical limiting process are presented, showing that nonlinear scattering is clearly the dominant mechanism in confrontation with other potential nonlinear effects. Several complementary experiments are then performed to complete the nonlinear scattering characterization, involving the measurement of the angular distribution of scattered energy and the integrating sphere measurement. Further information are also gained by studying the time response of the nonlinearities with a dual-beam (pulsed-pump, cw probe) technique. The previous experimental data is also analyzed with some simple theoretical models to evaluate the nonlinearity of the material from optical limiting, the angular scattering and the total scattering energy measurements. The good match between all the analytical results permits to delineate the physical mechanisms responsible for the nonlinear scattering effect and to direct the final conclusion. (author) [fr

  4. Numerical analysis of a non equilibrium two-component two-compressible flow in porous media

    KAUST Repository

    Saad, Bilal Mohammed; Saad, Mazen Naufal B M

    2013-01-01

    of the mass exchange between dissolved hydrogen and hydrogen in the gas phase is supposed finite. The proposed finite volume scheme is fully implicit in time together with a phase-by-phase upwind approach in space and it is discretize the equations

  5. Deconvoluting double Doppler spectra

    International Nuclear Information System (INIS)

    Ho, K.F.; Beling, C.D.; Fung, S.; Chan, K.L.; Tang, H.W.

    2001-01-01

    The successful deconvolution of data from double Doppler broadening of annihilation radiation (D-DBAR) spectroscopy is a promising area of endeavour aimed at producing momentum distributions of a quality comparable to those of the angular correlation technique. The deconvolution procedure we test in the present study is the constrained generalized least square method. Trials with computer simulated DDBAR spectra are generated and deconvoluted in order to find the best form of regularizer and the regularization parameter. For these trials the Neumann (reflective) boundary condition is used to give a single matrix operation in Fourier space. Experimental D-DBAR spectra are also subject to the same type of deconvolution after having carried out a background subtraction and using a symmetrize resolution function obtained from an 85 Sr source with wide coincidence windows. (orig.)

  6. Structural Basis for DNA Recognition by the Two-Component Response Regulator RcsB.

    Science.gov (United States)

    Filippova, Ekaterina V; Zemaitaitis, Bozena; Aung, Theint; Wolfe, Alan J; Anderson, Wayne F

    2018-02-27

    RcsB is a highly conserved transcription regulator of the Rcs phosphorelay system, a complex two-component signal transduction system (N. Majdalani and S. Gottesman, Annu Rev Microbiol 59:379-405, 2005; A. J. Wolfe, Curr Opin Microbiol 13:204-209, 2010, https://doi.org/10.1016/j.mib.2010.01.002; D. J. Clarke, Future Microbiol 5:1173-1184, 2010, https://doi.org/10.2217/fmb.10.83). RcsB plays an important role in virulence and pathogenicity in human hosts by regulating biofilm formation. RcsB can regulate transcription alone or together with its auxiliary transcription regulators by forming heterodimers. This complexity allows RcsB to regulate transcription of more than 600 bacterial genes in response to different stresses (D. Wang et al., Mol Plant Microbe Interact 25:6-17, 2012, https://doi.org/10.1094/MPMI-08-11-0207). Despite increasing knowledge of RcsB importance, molecular mechanisms that drive the ability of RcsB to control transcription of a large number of genes remain unclear. Here, we present crystal structures of unphosphorylated RcsB in complex with the consensus DNA-binding sequence of 22-mer (DNA22) and 18-mer (DNA18) of the flhDC operon from Escherichia coli determined at 3.15- and 3.37-Å resolution, respectively. The results of our structural analysis combined with the results of in vitro binding assays provide valuable insights to the protein regulatory mechanism, demonstrate how RcsB recognizes target DNA sequences, and reveal a unique oligomeric state that allows RcsB to form homo- and heterodimers. This information will help us understand the complex mechanisms of transcriptional regulation by RcsB in bacteria. IMPORTANCE RcsB is a well-studied two-component response regulator of the Rcs phosphorelay system, conserved within the family Enterobacteriaceae , which includes many pathogens. It is a global regulator, controlling more than 5% of bacterial genes associated with capsule biosynthesis, flagellar biogenesis, cell wall biosynthesis

  7. Counterbalancing Regulation in Response Memory of a Positively Autoregulated Two-Component System.

    Science.gov (United States)

    Gao, Rong; Godfrey, Katherine A; Sufian, Mahir A; Stock, Ann M

    2017-09-15

    Fluctuations in nutrient availability often result in recurrent exposures to the same stimulus conditions. The ability to memorize the past event and use the "memory" to make adjustments to current behaviors can lead to a more efficient adaptation to the recurring stimulus. A short-term phenotypic memory can be conferred via carryover of the response proteins to facilitate the recurrent response, but the additional accumulation of response proteins can lead to a deviation from response homeostasis. We used the Escherichia coli PhoB/PhoR two-component system (TCS) as a model system to study how cells cope with the recurrence of environmental phosphate (Pi) starvation conditions. We discovered that "memory" of prior Pi starvation can exert distinct effects through two regulatory pathways, the TCS signaling pathway and the stress response pathway. Although carryover of TCS proteins can lead to higher initial levels of transcription factor PhoB and a faster initial response in prestarved cells than in cells not starved, the response enhancement can be overcome by an earlier and greater repression of promoter activity in prestarved cells due to the memory of the stress response. The repression counterbalances the carryover of the response proteins, leading to a homeostatic response whether or not cells are prestimulated. A computational model based on sigma factor competition was developed to understand the memory of stress response and to predict the homeostasis of other PhoB-regulated response proteins. Our insight into the history-dependent PhoBR response may provide a general understanding of how TCSs respond to recurring stimuli and adapt to fluctuating environmental conditions. IMPORTANCE Bacterial cells in their natural environments experience scenarios that are far more complex than are typically replicated in laboratory experiments. The architectures of signaling systems and the integration of multiple adaptive pathways have evolved to deal with such complexity

  8. Counterbalancing Regulation in Response Memory of a Positively Autoregulated Two-Component System

    Science.gov (United States)

    Gao, Rong; Godfrey, Katherine A.; Sufian, Mahir A.

    2017-01-01

    ABSTRACT Fluctuations in nutrient availability often result in recurrent exposures to the same stimulus conditions. The ability to memorize the past event and use the “memory” to make adjustments to current behaviors can lead to a more efficient adaptation to the recurring stimulus. A short-term phenotypic memory can be conferred via carryover of the response proteins to facilitate the recurrent response, but the additional accumulation of response proteins can lead to a deviation from response homeostasis. We used the Escherichia coli PhoB/PhoR two-component system (TCS) as a model system to study how cells cope with the recurrence of environmental phosphate (Pi) starvation conditions. We discovered that “memory” of prior Pi starvation can exert distinct effects through two regulatory pathways, the TCS signaling pathway and the stress response pathway. Although carryover of TCS proteins can lead to higher initial levels of transcription factor PhoB and a faster initial response in prestarved cells than in cells not starved, the response enhancement can be overcome by an earlier and greater repression of promoter activity in prestarved cells due to the memory of the stress response. The repression counterbalances the carryover of the response proteins, leading to a homeostatic response whether or not cells are prestimulated. A computational model based on sigma factor competition was developed to understand the memory of stress response and to predict the homeostasis of other PhoB-regulated response proteins. Our insight into the history-dependent PhoBR response may provide a general understanding of how TCSs respond to recurring stimuli and adapt to fluctuating environmental conditions. IMPORTANCE Bacterial cells in their natural environments experience scenarios that are far more complex than are typically replicated in laboratory experiments. The architectures of signaling systems and the integration of multiple adaptive pathways have evolved to deal

  9. Identification by irradiation, in vitro, of two components of erythroprotein action

    International Nuclear Information System (INIS)

    Barcos, M.

    1978-01-01

    The effect of ionizing radiation on the response of normal cultured rat marrow cells to erythropoietin yielded two-component inactivation curves for induced iron uptake and hemoglobin synthesis. The radioresistant component of the induced hemoglobin response (1) was detected earlier, at 6 to 20 hr after irradiation, (2) had a DO 0 > or = to 900 R, (3) gave a nonlinear erythropoietin dose--response plot at 600 R, (4) disappeared when marrow from erythremic rats was used, and (5) showed maximal inactivation by 500 R when irradiation preceded hormone addition by 1.5 to 2.5 hr. The radiosensitive component (1) was observed without any contribution from the radioresistant component when the time of assay of normal marrow was postponed from 6 to 20 hr to 20 to 44 hr of culture, (2) had a D 0 = 63 R, (3) gave linear erythropoietin dose--response curves at 15 to 60 R, and (4) showed enhanced inhibition by 60 R if irradiation either preceded or followed hormone addition by 3 hr or more

  10. Modified Baryonic Dynamics: two-component cosmological simulations with light sterile neutrinos

    Energy Technology Data Exchange (ETDEWEB)

    Angus, G.W.; Gentile, G. [Department of Physics and Astrophysics, Vrije Universiteit Brussel, Pleinlaan 2, Brussels, 1050 Belgium (Belgium); Diaferio, A. [Dipartimento di Fisica, Università di Torino, Via P. Giuria 1, Torino, I-10125 Italy (Italy); Famaey, B. [Observatoire astronomique de Strasbourg, CNRS UMR 7550, Université de Strasbourg, 11 rue de l' Université, Strasbourg, F-67000 France (France); Heyden, K.J. van der, E-mail: garry.angus@vub.ac.be, E-mail: diaferio@ph.unito.it, E-mail: benoit.famaey@astro.unistra.fr, E-mail: gianfranco.gentile@ugent.be, E-mail: heyden@ast.uct.ac.za [Astrophysics, Cosmology and Gravity Centre, Dept. of Astronomy, University of Cape Town, Private Bag X3, Rondebosch, 7701 South Africa (South Africa)

    2014-10-01

    In this article we continue to test cosmological models centred on Modified Newtonian Dynamics (MOND) with light sterile neutrinos, which could in principle be a way to solve the fine-tuning problems of the standard model on galaxy scales while preserving successful predictions on larger scales. Due to previous failures of the simple MOND cosmological model, here we test a speculative model where the modified gravitational field is produced only by the baryons and the sterile neutrinos produce a purely Newtonian field (hence Modified Baryonic Dynamics). We use two-component cosmological simulations to separate the baryonic N-body particles from the sterile neutrino ones. The premise is to attenuate the over-production of massive galaxy cluster halos which were prevalent in the original MOND plus light sterile neutrinos scenario. Theoretical issues with such a formulation notwithstanding, the Modified Baryonic Dynamics model fails to produce the correct amplitude for the galaxy cluster mass function for any reasonable value of the primordial power spectrum normalisation.

  11. Quantum characteristics of occurrence scattering time in two-component non-ideal plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Woo-Pyo [Department of Electronics Engineering, Catholic University of Daegu, Hayang, 712-702 (Korea, Republic of); Jung, Young-Dae, E-mail: ydjung@hanyang.ac.kr [Department of Applied Physics and Department of Bionanotechnology, Hanyang University, Ansan, Kyunggi-Do 15588 (Korea, Republic of); Department of Physics, Applied Physics, and Astronomy, Rensselaer Polytechnic Institute, 110 8th Street, Troy, NY 12180-3590 (United States)

    2015-10-30

    The quantum diffraction and plasma screening effects on the occurrence time for the collision process are investigated in two-component non-ideal plasmas. The micropotential model taking into account the quantum diffraction and screening with the eikonal analysis is employed to derive the occurrence time as functions of the collision energy, density parameter, Debye length, de Broglie wavelength, and scattering angle. It is shown that the occurrence time for forward scattering directions decreases the tendency of time-advance with increasing scattering angle and de Broglie wavelength. However, it is found that the occurrence time shows the oscillatory time-advance and time-retarded behaviors with increasing scattering angle. It is found that the plasma screening effect enhances the tendency of time-advance on the occurrence time for forward scattering regions. It is also shown the quantum diffraction effect suppresses the occurrence time advance for forward scattering angles. In addition, it is shown that the occurrence time advance decreases with an increase of the collision energy. - Highlights: • The quantum diffraction and screening effects on the occurrence scattering time are investigated in non-ideal plasmas. • It is shown the quantum diffraction effect suppresses the occurrence time advance for forward scattering angles. • It is found that the plasma screening effect enhances the tendency of time-advance on the occurrence time.

  12. Determination of the number of and classification of two-component ionic-covalent chemical compounds

    International Nuclear Information System (INIS)

    Vigdorovich, V.N.; Dzhuraev, T.D.; Khanin, V.A.

    1989-01-01

    The aim of this work was to determine the number of and to classify two-component compounds corresponding to the four-electron and full-valence concepts and characterized by the ionic-covalent type of bond, on which the metallic bond is superimposed to a greater lesser degree. At the same time it was proposed to verify the position of the axes in the periodic system. The presence of numerous compound analogs for the element prototypes of one axis of the Mendeleev periodic system [the group of noble (inert) gases] was confirmed by computer experiments. However, the other axis (the carbon group) is not so obvious and is evidently due, on account of the superimposition of the effect of noncharacteristic (possible) valences, to the elements of various groups (boron, aluminum, germanium, antimony, bismuth). In addition, the compound analogs for the element prototypes of the d block are numerous, i.e., the copper-silver-gold, manganese-technetium-rhenium, and iron and platinum families

  13. Temporal evolution of photon energy emitted from two-component advective flows: origin of time lag

    Science.gov (United States)

    Chatterjee, Arka; Chakrabarti, Sandip K.; Ghosh, Himadri

    2017-12-01

    X-ray time lag of black hole candidates contains important information regarding the emission geometry. Recently, study of time lags from observational data revealed very intriguing properties. To investigate the real cause of this lag behavior with energy and spectral states, we study photon paths inside a two-component advective flow (TCAF) which appears to be a satisfactory model to explain the spectral and timing properties. We employ the Monte Carlo simulation technique to carry out the Comptonization process. We use a relativistic thick disk in Schwarzschild geometry as the CENtrifugal pressure supported BOundary Layer (CENBOL) which is the Compton cloud. In TCAF, this is the post-shock region of the advective component. Keplerian disk on the equatorial plane which is truncated at the inner edge i.e. at the outer boundary of the CENBOL, acts as the soft photon source. Ray-tracing code is employed to track the photons to a distantly located observer. We compute the cumulative time taken by a photon during Comptonization, reflection and following the curved geometry on the way to the observer. Time lags between various hard and soft bands have been calculated. We study the variation of time lags with accretion rates, CENBOL size and inclination angle. Time lags for different energy channels are plotted for different inclination angles. The general trend of variation of time lag with QPO frequency and energy as observed in satellite data is reproduced.

  14. A two component system is involved in acid adaptation of Lactobacillus delbrueckii subsp. bulgaricus.

    Science.gov (United States)

    Cui, Yanhua; Liu, Wei; Qu, Xiaojun; Chen, Zhangting; Zhang, Xu; Liu, Tong; Zhang, Lanwei

    2012-05-20

    The Gram-positive bacterium Lactobacillus delbrueckii subsp. bulgaricus is of vital importance to the food industry, especially to the dairy industry. Two component systems (TCSs) are one of the most important mechanisms for environmental sensing and signal transduction in the majority of Gram-positive and Gram-negative bacteria. A typical TCS consists of a histidine protein kinase (HPK) and a cytoplasmic response regulator (RR). To investigate the functions of TCSs during acid adaptation in L. bulgaricus, we used quantitative PCR to reveal how TCSs expression changes during acid adaptation. Two TCSs (JN675228/JN675229 and JN675230/JN675231) and two HPKs (JN675236 and JN675240) were induced during acid adaptation. These TCSs were speculated to be related with the acid adaptation ability of L. bulgaricus. The mutants of JN675228/JN675229 were constructed in order to investigate the functions of JN675228/JN675229. The mutants showed reduced acid adaptation compared to that of wild type, and the complemented strains were similar to the wild-type strain. These observations suggested that JN675228 and JN675229 were involved in acid adaptation in L. bulgaricus. The interaction between JN675228 and JN675229 was identified by means of yeast two-hybrid system. The results indicated there is interaction between JN675228 and JN675229. Crown Copyright © 2011. Published by Elsevier GmbH. All rights reserved.

  15. The Evolution of Two-Component Systems in Bacteria RevealsDifferent Strategies for Niche Adaptation

    Energy Technology Data Exchange (ETDEWEB)

    Alm, Eric; Huang, Katherine; Arkin, Adam

    2006-09-13

    Two-component systems including histidine protein kinasesrepresent the primary signal transduction paradigm in prokaryoticorganisms. To understand how these systems adapt to allow organisms todetect niche-specific signals, we analyzed the phylogenetic distributionof nearly 5000 histidine protein kinases from 207 sequenced prokaryoticgenomes. We found that many genomes carry a large repertoire of recentlyevolved signaling genes, which may reflect selective pressure to adapt tonew environmental conditions. Both lineage-specific gene family expansionand horizontal gene transfer play major roles in the introduction of newhistidine kinases into genomes; however, there are differences in howthese two evolutionary forces act. Genes imported via horizontal transferare more likely to retain their original functionality as inferred from asimilar complement of signaling domains, while gene family expansionaccompanied by domain shuffling appears to be a major source of novelgenetic diversity. Family expansion is the dominantsource of newhistidine kinase genes in the genomes most enriched in signalingproteins, and detailed analysis reveals that divergence in domainstructure and changes in expression patterns are hallmarks of recentexpansions. Finally, while these two modes of gene acquisition arewidespread across bacterial taxa, there are clear species-specificpreferences for which mode is used.

  16. PLA and two components silicon rubber blends aiming for frozen foods packaging applications

    Directory of Open Access Journals (Sweden)

    Utai Meekum

    2018-03-01

    Full Text Available Designing of PLA and two components silicone rubber blends was studies. Frozen food packaging application is the main ultimate aim. The statistical method using 23 DOE was conducted. The standard testing methods, in particular impact testing at sub-zero temperature, were performed. The preliminary blend formula comprised 1.0 phr of silane and polyester polyols, respectively, was initially resolved. Then, the optimize the silicone portion in the blends was determined. Blending formula using 8.0 phr of silicone with respect to PLA matrix gave rise to the overall satisfactory properties. 3. TETA was used as the silicone curing agent and reactively blended onto the ingredients. TETA at 0.4 phr, with respect to the silicone, enhanced the mechanical properties, especially flexibility and toughness, of the PLA/silicone blend. Exceeding the optimal TETA loading would cause the chain scission and also the dilution effects. Hence, marginal inferior properties of the blends were be experienced. The preliminary biodegradability investigation found that the PLA/silicone blend initially triggered at the second week. Its degradation rate was likely to be faster than neat PLA. Keywords: PLA/silicone blends, Mechanical properties, Sub-zero impact strength

  17. An inverse spectral problem related to the Geng-Xue two-component peakon equation

    CERN Document Server

    Lundmark, Hans

    2016-01-01

    The authors solve a spectral and an inverse spectral problem arising in the computation of peakon solutions to the two-component PDE derived by Geng and Xue as a generalization of the Novikov and Degasperisâe"Procesi equations. Like the spectral problems for those equations, this one is of a âeoediscrete cubic stringâe typeâe"a nonselfadjoint generalization of a classical inhomogeneous stringâe"but presents some interesting novel features: there are two Lax pairs, both of which contribute to the correct complete spectral data, and the solution to the inverse problem can be expressed using quantities related to Cauchy biorthogonal polynomials with two different spectral measures. The latter extends the range of previous applications of Cauchy biorthogonal polynomials to peakons, which featured either two identical, or two closely related, measures. The method used to solve the spectral problem hinges on the hidden presence of oscillatory kernels of Gantmacherâe"Krein type, implying that the spectrum of...

  18. Isomerization and dissociation in competition: the two-component dissociation rates of methyl acetate ions

    Science.gov (United States)

    Mazyar, Oleg A.; Mayer, Paul M.; Baer, Tomas

    1997-11-01

    Threshold photoelectron-photoion coincidence (TPEPICO) spectroscopy has been used to investigate the unimolecular chemistry of metastable methyl acetate ions, CH3COOCH3.+. The rate of molecular ion fragmentation with the loss of CH3O. and CH2OH radicals as a function of ion internal energy was obtained from the coincidence data and used in conjunction with Rice-Ramsperger-Kassel-Markus and ab initio molecular orbital calculations to model the dissociation/isomerization mechanism of the methyl acetate ion (A). The data were found to be consistent with the mechanism involving a hydrogen-bridged complex CH3CO[middle dot][middle dot][middle dot]H[middle dot][middle dot][middle dot]OCH2.+(E) as the direct precursor of the observed fragments CH3CO+ and CH2OH.. The two-component decay rates were modeled with a three-well-two-product potential energy surface including the distonic ion CH3C(OH)OCH2.+(B) and enol isomer CH2C(OH)OCH3.+(C), which are formed from the methyl acetate ion by two consecutive [1,4]-hydrogen shifts. The 0 K heats of formation of isomers B and C as well as transition states TSAB, TSBC, and TSBE (relative to isomer A) were calculated from Rice-Ramsperger-Kassel-Markus (RRKM) theory.

  19. Images and Spectra of Time Dependent Two Component Advective Flow in Presence of Outflows

    Science.gov (United States)

    Chatterjee, Arka; Chakrabarti, Sandip K.; Ghosh, Himadri; Garain, Sudip K.

    2018-05-01

    Two Component Advective Flow (TCAF) successfully explains the spectral and temporal properties of outbursting or persistent sources. Images of static TCAF with Compton cloud or CENtrifugal pressure supported Boundary Layer (CENBOL) due to gravitational bending of photons have been studied before. In this paper, we study time dependent images of advective flows around a Schwarzschild black hole which include cooling effects due to Comptonization of soft photons from a Keplerian disks well as the self-consistently produced jets and outflows. We show the overall image of the disk-jet system after convolving with a typical beamwidth. A long exposure image with time dependent system need not show the black hole horizon conspicuously, unless one is looking at a soft state with no jet or the system along the jet axis. Assuming these disk-jet configurations are relevant to radio emitting systems also, our results would be useful to look for event horizons in high accretion rate Supermassive Black Holes in Seyfert galaxies, RL Quasars.

  20. A two-component regulatory system controls autoregulated serpin expression in Bifidobacterium breve UCC2003.

    Science.gov (United States)

    Alvarez-Martin, Pablo; O'Connell Motherway, Mary; Turroni, Francesca; Foroni, Elena; Ventura, Marco; van Sinderen, Douwe

    2012-10-01

    This work reports on the identification and molecular characterization of a two-component regulatory system (2CRS), encoded by serRK, which is believed to control the expression of the ser(2003) locus in Bifidobacterium breve UCC2003. The ser(2003) locus consists of two genes, Bbr_1319 (sagA) and Bbr_1320 (serU), which are predicted to encode a hypothetical membrane-associated protein and a serpin-like protein, respectively. The response regulator SerR was shown to bind to the promoter region of ser(2003), and the probable recognition sequence of SerR was determined by a combinatorial approach of in vitro site-directed mutagenesis coupled to transcriptional fusion and electrophoretic mobility shift assays (EMSAs). The importance of the serRK 2CRS in the response of B. breve to protease-mediated induction was confirmed by generating a B. breve serR insertion mutant, which was shown to exhibit altered ser(2003) transcriptional induction patterns compared to the parent strain, UCC2003. Interestingly, the analysis of a B. breve serU mutant revealed that the SerRK signaling pathway appears to include a SerU-dependent autoregulatory loop.

  1. Two-component mixture cure rate model with spline estimated nonparametric components.

    Science.gov (United States)

    Wang, Lu; Du, Pang; Liang, Hua

    2012-09-01

    In some survival analysis of medical studies, there are often long-term survivors who can be considered as permanently cured. The goals in these studies are to estimate the noncured probability of the whole population and the hazard rate of the susceptible subpopulation. When covariates are present as often happens in practice, to understand covariate effects on the noncured probability and hazard rate is of equal importance. The existing methods are limited to parametric and semiparametric models. We propose a two-component mixture cure rate model with nonparametric forms for both the cure probability and the hazard rate function. Identifiability of the model is guaranteed by an additive assumption that allows no time-covariate interactions in the logarithm of hazard rate. Estimation is carried out by an expectation-maximization algorithm on maximizing a penalized likelihood. For inferential purpose, we apply the Louis formula to obtain point-wise confidence intervals for noncured probability and hazard rate. Asymptotic convergence rates of our function estimates are established. We then evaluate the proposed method by extensive simulations. We analyze the survival data from a melanoma study and find interesting patterns for this study. © 2011, The International Biometric Society.

  2. Development and characterization of two-component albedo based neutron individual monitoring system using thermoluminescent detectors

    International Nuclear Information System (INIS)

    Martins, Marcelo Marques

    2008-01-01

    A TLD-albedo based two-component neutron individual monitoring system was developed and characterized in this work. The monitor consists of a black plastic holder, an incident neutron boron loaded shield, a moderator polyethylene body (to increase its response), two pairs of TLD-600 and TLD-700 (one pair to each component) and an adjustable belt. This monitoring system was calibrated in thermal neutron fields and in 70 keV, 144 keV, 565 keV, 1.2 MeV and 5 MeV monoenergetic neutron fields. In addition, it was calibrated in 252C f(D 2 O), 252 Cf, 241 Am-B, 241 Am-Be and 238 Pu-Be source fields. For the latter, the lower detection levels are, respectively, 0.009 mSv, 0.06 mSv, 0.12 mSv, 0.09 mSv and 0.08 mSv. The participation in an international intercomparison sponsored by IAEA with simulated workplace fields validated the system. The monitoring system was successfully characterized in the ISO 21909 standard and in an IRD - the Brazilian Institute for Radioprotection and Dosimetry - technical regulation draft. Nowadays, the neutron individual system is in use by IRD for whole body individual monitoring of five institutions, which comprehend several activities. (author)

  3. Short and medium range order in two-component silica glasses by positron annihilation spectroscopy

    International Nuclear Information System (INIS)

    Inoue, K.; Kataoka, H.; Nagai, Y.; Hasegawa, M.; Kobayashi, Y.

    2014-01-01

    The dependence of chemical composition on the average sizes of subnanometer-scale intrinsic structural open spaces surrounded by glass random networks in two-component silica-based glasses was investigated systematically using positronium (Ps) confined in the open spaces. The average sizes of the open spaces for SiO 2 -B 2 O 3 and SiO 2 -GeO 2 glasses are only slightly dependent on the chemical compositions because the B 2 O 3 and GeO 2 are glass network formers that are incorporated into the glass network of the base SiO 2 . However, the open space sizes for all SiO 2 -R 2 O (R = Li, Na, K) glasses, where R 2 O is a glass network modifier that occupies the open spaces, decrease rapidly with an increase in the R 2 O concentration. Despite the large difference in the ionic radii of the alkali metal (R) atoms, the open space sizes decrease similarly for all the alkali metal atoms studied. This dependence of the chemical composition on the open space sizes in SiO 2 -R 2 O observed by Ps shows that the alkali metal atoms do not randomly occupy the structural open spaces, but filling of the open spaces by R 2 O proceeds selectively from the larger to the smaller open spaces as the R 2 O concentrations are increased.

  4. Adaptation to Environmental Stimuli within the Host: Two-Component Signal Transduction Systems of Mycobacterium tuberculosis

    Science.gov (United States)

    Bretl, Daniel J.; Demetriadou, Chrystalla; Zahrt, Thomas C.

    2011-01-01

    Summary: Pathogenic microorganisms encounter a variety of environmental stresses following infection of their respective hosts. Mycobacterium tuberculosis, the etiological agent of tuberculosis, is an unusual bacterial pathogen in that it is able to establish lifelong infections in individuals within granulomatous lesions that are formed following a productive immune response. Adaptation to this highly dynamic environment is thought to be mediated primarily through transcriptional reprogramming initiated in response to recognition of stimuli, including low-oxygen tension, nutrient depletion, reactive oxygen and nitrogen species, altered pH, toxic lipid moieties, cell wall/cell membrane-perturbing agents, and other environmental cues. To survive continued exposure to these potentially adverse factors, M. tuberculosis encodes a variety of regulatory factors, including 11 complete two-component signal transduction systems (TCSSs) and several orphaned response regulators (RRs) and sensor kinases (SKs). This report reviews our current knowledge of the TCSSs present in M. tuberculosis. In particular, we discuss the biochemical and functional characteristics of individual RRs and SKs, the environmental stimuli regulating their activation, the regulons controlled by the various TCSSs, and the known or postulated role(s) of individual TCSSs in the context of M. tuberculosis physiology and/or pathogenesis. PMID:22126994

  5. A hybrid two-component system protein from Azospirillum brasilense Sp7 was involved in chemotaxis.

    Science.gov (United States)

    Cui, Yanhua; Tu, Ran; Wu, Lixian; Hong, Yuanyuan; Chen, Sanfeng

    2011-09-20

    We here report the sequence and functional analysis of org35 of Azospirillum brasilense Sp7, which was originally identified to be able to interact with NifA in yeast-two-hybrid system. The org35 encodes a hybrid two-component system protein, including N-terminal PAS domains, a histidine kinase (HPK) domain and a response regulator (RR) domain in C-terminal. To determine the function of the Org35, a deletion-insertion mutant in PAS domain [named Sp7353] and a complemental strain Sp7353C were constructed. The mutant had reduced chemotaxis ability compared to that of wild-type, and the complemental strain was similar to the wild-type strain. These data suggested that the A. brasilense org35 played a key role in chemotaxis. Variants containing different domains of the org35 were expressed, and the functions of these domains were studied in vitro. Phosphorylation assays in vitro demonstrated that the HPK domain of Org35 possessed the autokinase activity and that the phosphorylated HPK was able to transfer phosphate groups to the RR domain. The result indicated Org35 was a phosphorylation-communicating protein. Copyright © 2010 Elsevier GmbH. All rights reserved.

  6. Discrete kink dynamics in hydrogen-bonded chains: The two-component model

    DEFF Research Database (Denmark)

    Karpan, V.M.; Zolotaryuk, Yaroslav; Christiansen, Peter Leth

    2004-01-01

    We study discrete topological solitary waves (kinks and antikinks) in two nonlinear diatomic chain models that describe the collective dynamics of proton transfers in one-dimensional hydrogen-bonded networks. The essential ingredients of the models are (i) a realistic (anharmonic) ion-proton inte......We study discrete topological solitary waves (kinks and antikinks) in two nonlinear diatomic chain models that describe the collective dynamics of proton transfers in one-dimensional hydrogen-bonded networks. The essential ingredients of the models are (i) a realistic (anharmonic) ion...... chain subject to a substrate with two optical bands), both providing a bistability of the hydrogen-bonded proton. Exact two-component (kink and antikink) discrete solutions for these models are found numerically. We compare the soliton solutions and their properties in both the one- (when the heavy ions...... principal differences, like a significant difference in the stability switchings behavior for the kinks and the antikinks. Water-filled carbon nanotubes are briefly discussed as possible realistic systems, where topological discrete (anti)kink states might exist....

  7. Thermodynamics and kinetics of interstitial diffusion in a two-component system

    International Nuclear Information System (INIS)

    McKee, R.A.

    1980-01-01

    Diffusion theory is developed for a two-component system in which only the interstitial element is mobile. A thermodynamic formalism is used in direct parallel with a kinetic theory to construct a mechanism-independent relationship between tracer- and chemical-diffusion coefficients. It is found that D/sup I/=(D-italic*/f)(1+partiallnγ/partiallnC). D/sup I/ is the intrinsic- or chemical-diffusion coefficient for the interstitial, D* is the tracer-diffusion coefficient, f is the correlation factor, and γ is the activity coefficient. This expression accounts for site exclusion, correlation, and drift effects that occur as the interstitial content changes. Generalized phenomenological coefficients that are determined in this analysis can be used for standard representations of diffusion in electric fields and temperature gradients. Moreover, the forms that the phenomenological coefficients take for the interstitial system are the same as those previously derived for vacancy diffusion. A test of this predicted relationship between tracer- and chemical-diffusion coefficients is developed using a comparison between theory and experiment for carbon diffusion in fcc iron

  8. Study of the catalytic selectivity of an aqueous two-component polyurethane system by ftir spectroscopy

    Directory of Open Access Journals (Sweden)

    Stamenković Jakov V.

    2003-01-01

    Full Text Available The difficulty in formulating a two component waterborne polyurethane, is the isocyanate-water side reaction, which can lead to gassing/foaming, loss of isocyanate functionality, low gloss and a reduced pot life. To compensate for this side reaction, these formulations usually contain a large excess of isocyanate. Tin compounds, especially dibutyltin dilaurate, are widely used in coatings as catalysts for the isocyanate/hydroxyl reaction. Because of the high aquatic toxicity of some organotin compounds, there has been an attempt to ban organotin compounds from all coating applications. As a general rule, organotin catalysts are not selective, they catalyze the reaction of isocyanates with both hydroxyl groups and water and also catalyze the hydrolysis of ester groups. One novel approach to control the water side reaction is the use of catalysts which selectively catalyze the isocyanate-polyol reaction and not the isocyanate-water reaction. The selectivity of a variety of metal catalysts (metal octoates, metal acetylacetonates and mangan chelates with mixed ligands to catalyze the preferred reaction was measured using the FTIR method.

  9. PLA and two components silicon rubber blends aiming for frozen foods packaging applications

    Science.gov (United States)

    Meekum, Utai; Khiansanoi, Apichart

    2018-03-01

    Designing of PLA and two components silicone rubber blends was studies. Frozen food packaging application is the main ultimate aim. The statistical method using 23 DOE was conducted. The standard testing methods, in particular impact testing at sub-zero temperature, were performed. The preliminary blend formula comprised 1.0 phr of silane and polyester polyols, respectively, was initially resolved. Then, the optimize the silicone portion in the blends was determined. Blending formula using 8.0 phr of silicone with respect to PLA matrix gave rise to the overall satisfactory properties. 3. TETA was used as the silicone curing agent and reactively blended onto the ingredients. TETA at 0.4 phr, with respect to the silicone, enhanced the mechanical properties, especially flexibility and toughness, of the PLA/silicone blend. Exceeding the optimal TETA loading would cause the chain scission and also the dilution effects. Hence, marginal inferior properties of the blends were be experienced. The preliminary biodegradability investigation found that the PLA/silicone blend initially triggered at the second week. Its degradation rate was likely to be faster than neat PLA.

  10. Transversal Doppler-Fizeau effect

    International Nuclear Information System (INIS)

    Subacius, E.

    1981-01-01

    The relativistic calculation of the Doppler-Fizeau effect foresees a second grade redshift due to the proper time dilation of a moving object. The relevance of this relativistic effect on astrophysical observation is discussed, herein. (Auhor) [pt

  11. Dual-Doppler Feasibility Study

    Science.gov (United States)

    Huddleston, Lisa L.

    2012-01-01

    When two or more Doppler weather radar systems are monitoring the same region, the Doppler velocities can be combined to form a three-dimensional (3-D) wind vector field thus providing for a more intuitive analysis of the wind field. A real-time display of the 3-D winds can assist forecasters in predicting the onset of convection and severe weather. The data can also be used to initialize local numerical weather prediction models. Two operational Doppler Radar systems are in the vicinity of Kennedy Space Center (KSC) and Cape Canaveral Air Force Station (CCAFS); these systems are operated by the 45th Space Wing (45 SW) and the National Weather Service Melbourne, Fla. (NWS MLB). Dual-Doppler applications were considered by the 45 SW in choosing the site for the new radar. Accordingly, the 45th Weather Squadron (45 WS), NWS MLB and the National Aeronautics and Space Administration tasked the Applied Meteorology Unit (AMU) to investigate the feasibility of establishing dual-Doppler capability using the two existing systems. This study investigated technical, hardware, and software requirements necessary to enable the establishment of a dual-Doppler capability. Review of the available literature pertaining to the dual-Doppler technique and consultation with experts revealed that the physical locations and resulting beam crossing angles of the 45 SW and NWS MLB radars make them ideally suited for a dual-Doppler capability. The dual-Doppler equations were derived to facilitate complete understanding of dual-Doppler synthesis; to determine the technical information requirements; and to determine the components of wind velocity from the equation of continuity and radial velocity data collected by the two Doppler radars. Analysis confirmed the suitability of the existing systems to provide the desired capability. In addition, it is possible that both 45 SW radar data and Terminal Doppler Weather Radar data from Orlando International Airport could be used to alleviate any

  12. Doppler ultrasound scan during normal gestation: umbilical circulation; Ecografia Doppler en la gestacion normal: circulacion umbilical

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz, T.; Sabate, J.; Martinez-Benavides, M. M.; Sanchez-Ramos, J. [Hospital Virgen Macarena. Sevilla (Spain)

    2002-07-01

    To determine normal umbilical circulation patterns by means of Doppler ultrasound scan in a healthy gestating population without risk factors and with normal perinatal results, and to evaluate any occurring modifications relative to gestational age by obtaining records kept during pregnancy. One hundred and sixteen pregnant women carrying a single fetus have been studied. These women had no risk factors, with both clinical and analytical controls, as well as ultrasound scans, all being normal. There were performed a total of 193 Doppler ultrasound scans between weeks 15 and 41 of gestation, with blood-flow analysis in the arteries and vein of the umbilical cord. The obtained information was correlated with parameters that evaluate fetal well-being (fetal monitoring and/or oxytocin test) and perinatal result (delivery type, birth weight, Apgar score). Statistical analysis was performed with the programs SPSS 6.0.1 for Windows and EPIINFO 6.0.4. With pulsed Doppler, the umbilical artery in all cases demonstrated a biphasic morphology with systolic and diastolic components and without retrograde blood flow. As the gestation period increased, there was observed a progressive decrease in resistance along with an increase in blood-flow velocity during the diastolic phase. The Doppler ultrasound scan is a non-invasive method that permits the hemodynamic study of umbilical blood circulation. A knowledge of normal blood-flow signal morphology, as well as of the normal values for Doppler indices in relation to gestational age would permit us to utilize this method in high-risk pregnancies. (Author) 30 refs.

  13. Numerical analysis of mixing process of two component gases in vertical fluid layer

    International Nuclear Information System (INIS)

    Hatori, Hirofumi; Takeda, Tetsuaki; Funatani, Shumpei

    2015-01-01

    When the depressurization accident occurs in the Very-High-Temperature Reactor (VHTR), it is expected that air enter into the reactor core. Therefore, it is important to know a mixing process of different kind of gases in the stable or unstable stratified fluid layer. Especially, it is also important to examine an influence of localized natural convection and molecular diffusion on mixing process from a viewpoint of safety. In order to research the mixing process of two component gases and flow characteristics of the localized natural convection, we have carried out numerical analysis using three dimensional CFD code. The numerical model was consisted of a storage tank and a reverse U-shaped vertical slot. They were separated by a partition plate. One side of the left vertical fluid layer was heated and the other side was cooled. The right vertical fluid layer was also cooled. The procedure of numerical analysis is as follows. Firstly, the storage tank was filled with heavy gas and the reverse U-shaped vertical slot was filled with light gas. In the left vertical fluid layer, the localized natural convection was generated by the temperature difference between the vertical walls. The flow characteristics were obtained by a steady state analysis. The unsteady state analysis was started when the partition plate was opened. The gases were mixed by molecular diffusion and natural convection. After the time elapsed, natural circulation occurred. The result obtained in this numerical analysis is as follows. The temperature difference of the left vertical fluid layer was set to 100 K. The combination of the mixed gas was nitrogen and argon. After 76 minutes elapsed, natural circulation occurred. (author)

  14. Structural studies of the activation of the two component receiver domain NTRC by multidimensional heteronuclear NMR

    Energy Technology Data Exchange (ETDEWEB)

    Nohaile, Michael James [Univ. of California, Berkeley, CA (United States). Dept. of Chemistry

    1996-05-01

    Multidimensional heteronuclear NMR spectroscopy was used to investigate the N-terminal domain of the transcriptional enhancer NTRC (NiTrogen Regulatory protein C). This domain belongs to the family of receiver domains of two-component regulatory systems involved in signal transduction. Phosphorylation of NTRC at D54 leads to an activated form of the molecule which stimulates transcription of genes involved in nitrogen regulation. Three and four dimensional NMR techniques were used to determine an intermediate resolution structure of the unphosphorylated, inactive form of the N-terminal domain of NTRC. The structure is comprised of five α-helices and a five-stranded β-sheet in a (β/α)5 topology. Analysis of the backbone dynamics of NTRC indicate that helix 4 and strand 5 are significantly more flexible than the rest of the secondary structure of the protein and that the loops making up the active site are flexible. The short lifetime of phospho-NTRC hampers the study of this form. However, conditions for determining the resonance assignments and, possibly, the three dimensional structure of phosphorylated NTRC have been obtained. Tentative assignments of the phosphorylated form indicate that the majority of the changes that NTRC experiences upon phosphorylation occur in helix 3, strand 4, helix 4, strand 5, and the loop between strand 5 and helix 5 (the 3445 face of NTRC) as well as near the site of phosphorylation. In order to examine a stable, activated form of the protein, constitutively active mutants of NTRC were investigated.

  15. A second order anti-diffusive Lagrange-remap scheme for two-component flows

    Directory of Open Access Journals (Sweden)

    Lagoutière Frédéric

    2011-11-01

    Full Text Available We build a non-dissipative second order algorithm for the approximate resolution of the one-dimensional Euler system of compressible gas dynamics with two components. The considered model was proposed in [1]. The algorithm is based on [8] which deals with a non-dissipative first order resolution in Lagrange-remap formalism. In the present paper we describe, in the same framework, an algorithm that is second order accurate in time and space, and that preserves sharp interfaces. Numerical results reported at the end of the paper are very encouraging, showing the interest of the second order accuracy for genuinely non-linear waves. Nous construisons un algorithme d’ordre deux et non dissipatif pour la résolution approchée des équations d’Euler de la dynamique des gaz compressibles à deux constituants en dimension un. Le modèle que nous considérons est celui à cinq équations proposé et analysé dans [1]. L’algorithme est basé sur [8] qui proposait une résolution approchée à l’ordre un et non dissipative au moyen d’un splitting de type Lagrange-projection. Dans le présent article, nous décrivons, dans le même formalisme, un algorithme d’ordre deux en temps et en espace, qui préserve des interfaces « parfaites » entre les constituants. Les résultats numériques rapportés à la fin de l’article sont très encourageants ; ils montrent clairement les avantages d’un schéma d’ordre deux pour les ondes vraiment non linéaires.

  16. Transcriptome analysis of the Brucella abortus BvrR/BvrS two-component regulatory system.

    Directory of Open Access Journals (Sweden)

    Cristina Viadas

    Full Text Available BACKGROUND: The two-component BvrR/BvrS system is essential for Brucella abortus virulence. It was shown previously that its dysfunction alters the expression of some major outer membrane proteins and the pattern of lipid A acylation. To determine the genes regulated by BvrR/BvrS, we performed a whole-genome microarray analysis using B. abortus RNA obtained from wild type and bvrR mutant cells grown in the same conditions. METHODOLOGY/PRINCIPAL FINDINGS: A total of 127 differentially expressed genes were found: 83 were over expressed and 44 were less expressed in the bvrR mutant. Two operons, the phosphotransferase system and the maltose transport system, were down-regulated. Several genes involved in cell envelope or outer membrane biogenesis were differentially expressed: genes for outer membrane proteins (omp25a, omp25d, lipoproteins, LPS and fatty acid biosynthesis, stress response proteins, chaperones, flagellar genes, and twelve genes encoding ABC transport systems. Ten genes related with carbon metabolism (pckA and fumB among others were up-regulated in the bvrR mutant, and denitrification genes (nirK, norC and nosZ were also regulated. Notably, seven transcriptional regulators were affected, including VjbR, ExoR and OmpR that were less expressed in the bvrR mutant. Finally, the expression of eleven genes which have been previously related with Brucella virulence was also altered. CONCLUSIONS/SIGNIFICANCE: All these data corroborate the impact of BvrR/BvrS on cell envelope modulation, confirm that this system controls the carbon and nitrogen metabolism, and suggest a cross-talk among some regulators to adjust the Brucella physiology to the shift expected to occur during the transit from the extracellular to the intracellular niche.

  17. Salivaricin P, One of a Family of Two-Component Antilisterial Bacteriocins Produced by Intestinal Isolates of Lactobacillus salivarius▿

    Science.gov (United States)

    Barrett, Eoin; Hayes, Maria; O'Connor, Paula; Gardiner, Gillian; Fitzgerald, Gerald F.; Stanton, Catherine; Ross, R. Paul; Hill, Colin

    2007-01-01

    Lactobacillus salivarius DPC6005, a porcine intestinal isolate, produces a two-component bacteriocin, salivaricin P, with homology to ABP-118 produced by a human probiotic L. salivarius strain. Indeed, molecular characterization revealed that while the peptides Sln1 and ABP-118α are identical, their companion peptides (Sln2 and ABP-118β, respectively) differ by two amino acids. This observation suggests that two-component bacteriocins may be a common feature of intestinal L. salivarius strains. PMID:17416691

  18. Cloning of a two-component signal transduction system of Xanthomonas campestris pv. phaseoli var. fuscans strain BXPF65

    DEFF Research Database (Denmark)

    Chan, JWYF; Maynard, Scott; Goodwin, PH

    1998-01-01

    A putative two-component signal transduction system was amplified and cloned from the plant pathogenic bacterium Xanthomonas campestris pv. phaseoli var. fuscans isolate BXPF65. The 620 bp amplified fragment was sequenced and analyzed with the BLAST Enhanced Alignment Utility (BEAUTY). BEAUTY...... that the putative histidine kinase has homology with conserved “transmitter” domains of sensor proteins in two-component signal transduction systems. RFLP analysis using the putative signal transduction system showed polymorphisms among the strains....

  19. A two-component generalization of the reduced Ostrovsky equation and its integrable semi-discrete analogue

    International Nuclear Information System (INIS)

    Feng, Bao-Feng; Maruno, Ken-ichi; Ohta, Yasuhiro

    2017-01-01

    In the present paper, we propose a two-component generalization of the reduced Ostrovsky (Vakhnenko) equation, whose differential form can be viewed as the short-wave limit of a two-component Degasperis–Procesi (DP) equation. They are integrable due to the existence of Lax pairs. Moreover, we have shown that the two-component reduced Ostrovsky equation can be reduced from an extended BKP hierarchy with negative flow through a pseudo 3-reduction and a hodograph (reciprocal) transform. As a by-product, its bilinear form and N -soliton solution in terms of pfaffians are presented. One- and two-soliton solutions are provided and analyzed. In the second part of the paper, we start with a modified BKP hierarchy, which is a Bäcklund transformation of the above extended BKP hierarchy, an integrable semi-discrete analogue of the two-component reduced Ostrovsky equation is constructed by defining an appropriate discrete hodograph transform and dependent variable transformations. In particular, the backward difference form of above semi-discrete two-component reduced Ostrovsky equation gives rise to the integrable semi-discretization of the short wave limit of a two-component DP equation. Their N -soliton solutions in terms of pffafians are also provided. (paper)

  20. Exploring the Validity Range of the Polarimetric Two-Scale Two-Component Model for Soil Moisture Retrieval by Using AGRISAR Data

    Science.gov (United States)

    Di Martino, Gerardo; Iodice, Antonio; Natale, Antonio; Riccio, Daniele; Ruello, Giuseppe

    2015-04-01

    The recently proposed polarimetric two-scale two- component model (PTSTCM) in principle allows us obtaining a reasonable estimation of the soil moisture even in moderately vegetated areas, where the volumetric scattering contribution is non-negligible, provided that the surface component is dominant and the double-bounce component is negligible. Here we test the PTSTCM validity range by applying it to polarimetric SAR data acquired on areas for which, at the same times of SAR acquisitions, ground measurements of soil moisture were performed. In particular, we employ the AGRISAR'06 database, which includes data from several fields covering a period that spans all the phases of vegetation growth.

  1. A comparative experimental evaluation of uncertainty estimation methods for two-component PIV

    Science.gov (United States)

    Boomsma, Aaron; Bhattacharya, Sayantan; Troolin, Dan; Pothos, Stamatios; Vlachos, Pavlos

    2016-09-01

    Uncertainty quantification in planar particle image velocimetry (PIV) measurement is critical for proper assessment of the quality and significance of reported results. New uncertainty estimation methods have been recently introduced generating interest about their applicability and utility. The present study compares and contrasts current methods, across two separate experiments and three software packages in order to provide a diversified assessment of the methods. We evaluated the performance of four uncertainty estimation methods, primary peak ratio (PPR), mutual information (MI), image matching (IM) and correlation statistics (CS). The PPR method was implemented and tested in two processing codes, using in-house open source PIV processing software (PRANA, Purdue University) and Insight4G (TSI, Inc.). The MI method was evaluated in PRANA, as was the IM method. The CS method was evaluated using DaVis (LaVision, GmbH). Utilizing two PIV systems for high and low-resolution measurements and a laser doppler velocimetry (LDV) system, data were acquired in a total of three cases: a jet flow and a cylinder in cross flow at two Reynolds numbers. LDV measurements were used to establish a point validation against which the high-resolution PIV measurements were validated. Subsequently, the high-resolution PIV measurements were used as a reference against which the low-resolution PIV data were assessed for error and uncertainty. We compared error and uncertainty distributions, spatially varying RMS error and RMS uncertainty, and standard uncertainty coverages. We observed that qualitatively, each method responded to spatially varying error (i.e. higher error regions resulted in higher uncertainty predictions in that region). However, the PPR and MI methods demonstrated reduced uncertainty dynamic range response. In contrast, the IM and CS methods showed better response, but under-predicted the uncertainty ranges. The standard coverages (68% confidence interval) ranged from

  2. A comparative experimental evaluation of uncertainty estimation methods for two-component PIV

    International Nuclear Information System (INIS)

    Boomsma, Aaron; Troolin, Dan; Pothos, Stamatios; Bhattacharya, Sayantan; Vlachos, Pavlos

    2016-01-01

    Uncertainty quantification in planar particle image velocimetry (PIV) measurement is critical for proper assessment of the quality and significance of reported results. New uncertainty estimation methods have been recently introduced generating interest about their applicability and utility. The present study compares and contrasts current methods, across two separate experiments and three software packages in order to provide a diversified assessment of the methods. We evaluated the performance of four uncertainty estimation methods, primary peak ratio (PPR), mutual information (MI), image matching (IM) and correlation statistics (CS). The PPR method was implemented and tested in two processing codes, using in-house open source PIV processing software (PRANA, Purdue University) and Insight4G (TSI, Inc.). The MI method was evaluated in PRANA, as was the IM method. The CS method was evaluated using DaVis (LaVision, GmbH). Utilizing two PIV systems for high and low-resolution measurements and a laser doppler velocimetry (LDV) system, data were acquired in a total of three cases: a jet flow and a cylinder in cross flow at two Reynolds numbers. LDV measurements were used to establish a point validation against which the high-resolution PIV measurements were validated. Subsequently, the high-resolution PIV measurements were used as a reference against which the low-resolution PIV data were assessed for error and uncertainty. We compared error and uncertainty distributions, spatially varying RMS error and RMS uncertainty, and standard uncertainty coverages. We observed that qualitatively, each method responded to spatially varying error (i.e. higher error regions resulted in higher uncertainty predictions in that region). However, the PPR and MI methods demonstrated reduced uncertainty dynamic range response. In contrast, the IM and CS methods showed better response, but under-predicted the uncertainty ranges. The standard coverages (68% confidence interval) ranged from

  3. Passive emitter location with Doppler frequency and interferometric measurements

    NARCIS (Netherlands)

    Groot, J.S.; Dam, F.A.M.; Theil, A.

    2008-01-01

    Ground based emitters can be located with a receiver installed on an airborne platform. This paper discusses techniques based on Doppler frequency and differential phase measurements (interferometry). Measurements of the first technique are provided, while we discuss and compare the theoretical

  4. Two-component wind fields over ocean waves using atmospheric lidar and motion estimation algorithms

    Science.gov (United States)

    Mayor, S. D.

    2016-02-01

    Numerical models, such as large eddy simulations, are capable of providing stunning visualizations of the air-sea interface. One reason for this is the inherent spatial nature of such models. As compute power grows, models are able to provide higher resolution visualizations over larger domains revealing intricate details of the interactions of ocean waves and the airflow over them. Spatial observations on the other hand, which are necessary to validate the simulations, appear to lag behind models. The rough ocean environment of the real world is an additional challenge. One method of providing spatial observations of fluid flow is that of particle image velocimetry (PIV). PIV has been successfully applied to many problems in engineering and the geosciences. This presentation will show recent research results that demonstate that a PIV-style approach using pulsed-fiber atmospheric elastic backscatter lidar hardware and wavelet-based optical flow motion estimation software can reveal two-component wind fields over rough ocean surfaces. Namely, a recently-developed compact lidar was deployed for 10 days in March of 2015 in the Eureka, California area. It scanned over the ocean. Imagery reveal that breaking ocean waves provide copius amounts of particulate matter for the lidar to detect and for the motion estimation algorithms to retrieve wind vectors from. The image below shows two examples of results from the experiment. The left panel shows the elastic backscatter intensity (copper shades) under a field of vectors that was retrieved by the wavelet-based optical flow algorithm from two scans that took about 15 s each to acquire. The vectors, that reveal offshore flow toward the NW, were decimated for clarity. The bright aerosol features along the right edge of the sector scan were caused by ocean waves breaking on the beach. The right panel is the result of scanning over the ocean on a day when wave amplitudes ranged from 8-12 feet and whitecaps offshore beyond the

  5. Evolutionary tuning of protein expression levels of a positively autoregulated two-component system.

    Directory of Open Access Journals (Sweden)

    Rong Gao

    2013-10-01

    Full Text Available Cellular adaptation relies on the development of proper regulatory schemes for accurate control of gene expression levels in response to environmental cues. Over- or under-expression can lead to diminished cell fitness due to increased costs or insufficient benefits. Positive autoregulation is a common regulatory scheme that controls protein expression levels and gives rise to essential features in diverse signaling systems, yet its roles in cell fitness are less understood. It remains largely unknown how much protein expression is 'appropriate' for optimal cell fitness under specific extracellular conditions and how the dynamic environment shapes the regulatory scheme to reach appropriate expression levels. Here, we investigate the correlation of cell fitness and output response with protein expression levels of the E. coli PhoB/PhoR two-component system (TCS. In response to phosphate (Pi-depletion, the PhoB/PhoR system activates genes involved in phosphorus assimilation as well as genes encoding themselves, similarly to many other positively autoregulated TCSs. We developed a bacteria competition assay in continuous cultures and discovered that different Pi conditions have conflicting requirements of protein expression levels for optimal cell fitness. Pi-replete conditions favored cells with low levels of PhoB/PhoR while Pi-deplete conditions selected for cells with high levels of PhoB/PhoR. These two levels matched PhoB/PhoR concentrations achieved via positive autoregulation in wild-type cells under Pi-replete and -deplete conditions, respectively. The fitness optimum correlates with the wild-type expression level, above which the phosphorylation output saturates, thus further increase in expression presumably provides no additional benefits. Laboratory evolution experiments further indicate that cells with non-ideal protein levels can evolve toward the optimal levels with diverse mutational strategies. Our results suggest that the natural

  6. Characterization of an archaeal two-component system that regulates methanogenesis in Methanosaeta harundinacea.

    Directory of Open Access Journals (Sweden)

    Jie Li

    Full Text Available Two-component signal transduction systems (TCSs are a major mechanism used by bacteria in response to environmental changes. Although many sequenced archaeal genomes encode TCSs, they remain poorly understood. Previously, we reported that a methanogenic archaeon, Methanosaeta harundinacea, encodes FilI, which synthesizes carboxyl-acyl homoserine lactones, to regulate transitions of cellular morphology and carbon metabolic fluxes. Here, we report that filI, the cotranscribed filR2, and the adjacent filR1 constitute an archaeal TCS. FilI possesses a cytoplasmic kinase domain (histidine kinase A and histidine kinase-like ATPase and its cognate response regulator. FilR1 carries a receiver (REC domain coupled with an ArsR-related domain with potential DNA-binding ability, while FilR2 carries only a REC domain. In a phosphorelay assay, FilI was autophosphorylated and specifically transferred the phosphoryl group to FilR1 and FilR2, confirming that the three formed a cognate TCS. Through chromatin immunoprecipitation-quantitative polymerase chain reaction (ChIP-qPCR using an anti-FilR1 antibody, FilR1 was shown to form in vivo associations with its own promoter and the promoter of the filI-filR2 operon, demonstrating a regulatory pattern common among TCSs. ChIP-qPCR also detected FilR1 associations with key genes involved in acetoclastic methanogenesis, acs4 and acs1. Electrophoretic mobility shift assays confirmed the in vitro tight binding of FilR1 to its own promoter and those of filI-filR2, acs4, and mtrABC. This also proves the DNA-binding ability of the ArsR-related domain, which is found primarily in Archaea. The archaeal promoters of acs4, filI, acs1, and mtrABC also initiated FilR1-modulated expression in an Escherichia coli lux reporter system, suggesting that FilR1 can up-regulate both archaeal and bacterial transcription. In conclusion, this work identifies an archaeal FilI/FilRs TCS that regulates the methanogenesis of M. harundinacea.

  7. Biomimetic Nanofibrillation in Two-Component Biopolymer Blends with Structural Analogs to Spider Silk

    Science.gov (United States)

    Xie, Lan; Xu, Huan; Li, Liang-Bin; Hsiao, Benjamin S.; Zhong, Gan-Ji; Li, Zhong-Ming

    2016-10-01

    Despite the enormous potential in bioinspired fabrication of high-strength structure by mimicking the spinning process of spider silk, currently accessible routes (e.g., microfluidic and electrospinning approaches) still have substantial function gaps in providing precision control over the nanofibrillar superstructure, crystalline morphology or molecular orientation. Here the concept of biomimetic nanofibrillation, by copying the spiders’ spinning principles, was conceived to build silk-mimicking hierarchies in two-phase biodegradable blends, strategically involving the stepwise integration of elongational shear and high-pressure shear. Phase separation confined on nanoscale, together with deformation of discrete phases and pre-alignment of polymer chains, was triggered in the elongational shear, conferring the readiness for direct nanofibrillation in the latter shearing stage. The orderly aligned nanofibrils, featuring an ultralow diameter of around 100 nm and the “rigid-soft” system crosslinked by nanocrystal domains like silk protein dopes, were secreted by fine nanochannels. The incorporation of multiscale silk-mimicking structures afforded exceptional combination of strength, ductility and toughness for the nanofibrillar polymer composites. The proposed spider spinning-mimicking strategy, offering the biomimetic function integration unattainable with current approaches, may prompt materials scientists to pursue biopolymer mimics of silk with high performance yet light weight.

  8. Doppler echocardiography in pediatric cardiology

    International Nuclear Information System (INIS)

    Allen, H.D.; Marx, G.R.

    1986-01-01

    Congenital heart disease encompasses abnormalities in cardiac development which generally have in common either valve stenoses or connections between chambers or great vessels. Usually, abnormalities of intracardiac anatomy, and often, abnormalities of great vessel anatomy, can be unraveled by two-dimensional echocardiography. However, echocardiography offers little information regarding flow characteristics in the various congenital lesions. Addition of the Doppler principle, particularly when combined with the two-dimensional examination, can characterize the source of a flow disturbance, quantify gradients across a site of obstruction, and quantify flow volume across sites where flow is nonturbulent. These features make Doppler echocardiography unique for noninvasive accurate evaluation of children and adults with various forms of congenital heart disease. In this report, the authors discuss some of the present uses of Doppler echocardiography in congenital heart disease. Application of this technique requires greater understanding of certain physics principles than does routine echocardiography

  9. New clutter-rejection algorithm for Doppler ultrasound

    Science.gov (United States)

    Cloutier, Guy; Chen, Danmin; Durand, Louis-Gilles

    2002-04-01

    Several strategies, known as clutter or wall Doppler filtering, were proposed to remove the strong echoes produced by stationary or slow moving tissue structures from the Doppler blood flow signal. In this study, the matching pursuit (MP) method is proposed to remove clutter components. The MP method decomposes the Doppler signal into wavelet atoms that are selected in a decreasing energy order. Thus, the high-energy clutter components are extracted first. In the present study, the pulsatile Doppler signal s(n) was simulated by a sum of random-phase sinusoids. Two types of high-amplitude clutter signals were then superimposed on s(n): a time-varying low frequency component (type 1), covering systole and early diastole, and short transient clutter signals (type 2), distributed within the whole cardiac cycle. The Doppler signals were modeled with the MP method and the most dominant atoms were subtracted until the signal-to-clutter (S/C) ratio reached a maximum. For the type 1 clutter signal, the improvement in the S/C ratio was 19.0 +/- 0.6 dB, and 72.0 +/- 4.5 atoms were required to reach this performance. For the transient type 2 clutter signal, exactly 10 atoms were required and the maximum improvement in S/C ratio was 5.5 +/- 0.5 dB. These results suggest the possibility of using this signal processing approach to implement clutter rejection filters on ultrasound commercial instruments.

  10. Experimental investigation of the factors influencing the polymer-polymer bond strength during two component injection moulding

    DEFF Research Database (Denmark)

    Islam, Mohammad Aminul; Hansen, Hans Nørgaard; Tang, Peter Torben

    2007-01-01

    Two component injection moulding is a commercially important manufacturing process and a key technology for Moulded Interconnect Devices (MIDs). Many fascinating applications of two component or multi component polymer parts are restricted due to the weak interfacial adhesion of the polymers...... effectively control the adhesion between two polymers. The effects of environmental conditions on the bond strength after moulding are also investigated. The material selections and environmental conditions were chosen based on the suitability of MID production, but the results and discussion presented....... A thorough understanding of the factors that influence the bond strength of polymers is necessary for multi component polymer processing. This paper investigates the effects of the process and material parameters on the bond strength of two component polymer parts and identifies the factors which can...

  11. Experimental investigation of the factors influencing the polymer-polymer bond strength during two-component injection moulding

    DEFF Research Database (Denmark)

    Islam, Aminul; Hansen, Hans Nørgaard; Bondo, Martin

    2010-01-01

    Two-component injection moulding is a commercially important manufacturing process and a key technology for combining different material properties in a single plastic product. It is also one of most industrially adaptive process chain for manufacturing so-called moulded interconnect devices (MIDs......). Many fascinating applications of two-component or multi-component polymer parts are restricted due to the weak interfacial adhesion of the polymers. A thorough understanding of the factors that influence the bond strength of polymers is necessary for multi-component polymer processing. This paper...... investigates the effects of the process conditions and geometrical factors on the bond strength of two-component polymer parts and identifies the factors which can effectively control the adhesion between two polymers. The effects of environmental conditions on the bond strength are also investigated...

  12. Bacillus subtilis Two-Component System Sensory Kinase DegS Is Regulated by Serine Phosphorylation in Its Input Domain

    DEFF Research Database (Denmark)

    Jers, Carsten; Kobir, Ahasanul; Søndergaard, Elsebeth Oline

    2011-01-01

    Bacillus subtilis two-component system DegS/U is well known for the complexity of its regulation. The cytosolic sensory kinase DegS does not receive a single predominant input signal like most two-component kinases, instead it integrates a wide array of metabolic inputs that modulate its activity......S phosphorylation can be carried out by at least two B. subtilis Hanks-type kinases in vitro, and this stimulates the phosphate transfer towards DegU. The consequences of this process were studied in vivo, using phosphomimetic (Ser76Asp) and non-phosphorylatable (Ser76Ala) mutants of DegS. In a number...

  13. Mixing efficiency inside micro-droplets coalesced by two components in cross-structure

    Science.gov (United States)

    Ren, Yanlin; Liu, Zhaomiao; Pang, Yan

    2017-11-01

    The mixing of micro-droplets is used in analytical chemistry, medicine production and material synthesis owing to its advantages including the encapsulation and narrow time residence distribution. In this work, droplets are coalesced by two dispersed phase with different flow rates, generated in cross-structure and mixed in planar serpentine structure. The mixing efficiency of micro-droplets under control characters including the width of entrance and the flow rate of dispersed phases have been investigated by experiments and numerical simulations. The UDS (user-defined scalar) as dimensionless concentration of the solution is adopted in simulation, and is used to calculate the concentration and the mixing effect. By changing the flow rates and the entrances` width, the changing rules of the mixing characters have been obtained. The asymmetry distributions of components make rapid mixing process in half part of each droplet when travel through a straight channel. Increasing of the ratio of entrance width result into larger droplet and weaken the chaotic mixing effect. Meanwhile, the coalesced mechanism can be performed by ranging the ratio of flow rates, the ranges are also determined by the widths of entrances. The authors gratefully acknowledge the support of National Natural Science Foundation of China (Grant No. 11572013).

  14. Immediate and heterogeneous response of the LiaFSR two-component system of Bacillus subtilis to the peptide antibiotic bacitracin.

    Science.gov (United States)

    Kesel, Sara; Mader, Andreas; Höfler, Carolin; Mascher, Thorsten; Leisner, Madeleine

    2013-01-01

    Two-component signal transduction systems are one means of bacteria to respond to external stimuli. The LiaFSR two-component system of Bacillus subtilis consists of a regular two-component system LiaRS comprising the core Histidine Kinase (HK) LiaS and the Response Regulator (RR) LiaR and additionally the accessory protein LiaF, which acts as a negative regulator of LiaRS-dependent signal transduction. The complete LiaFSR system was shown to respond to various peptide antibiotics interfering with cell wall biosynthesis, including bacitracin. Here we study the response of the LiaFSR system to various concentrations of the peptide antibiotic bacitracin. Using quantitative fluorescence microscopy, we performed a whole population study analyzed on the single cell level. We investigated switching from the non-induced 'OFF' state into the bacitracin-induced 'ON' state by monitoring gene expression of a fluorescent reporter from the RR-regulated liaI promoter. We found that switching into the 'ON' state occurred within less than 20 min in a well-defined switching window, independent of the bacitracin concentration. The switching rate and the basal expression rate decreased at low bacitracin concentrations, establishing clear heterogeneity 60 min after bacitracin induction. Finally, we performed time-lapse microscopy of single cells confirming the quantitative response as obtained in the whole population analysis for high bacitracin concentrations. The LiaFSR system exhibits an immediate, heterogeneous and graded response to the inducer bacitracin in the exponential growth phase.

  15. Doppler broadening of cross sections

    International Nuclear Information System (INIS)

    Buckler, P.A.C.; Pull, I.C.

    1962-12-01

    Expressions for temperature dependent cross-sections in terms of resonance parameters are obtained, involving generalisations of the conventional Doppler functions, ψ and φ. Descriptions of Fortran sub-routines, which calculate broadened cross-sections in accordance with the derived formulae, are included. (author)

  16. Speed of light demonstration using Doppler beat

    Science.gov (United States)

    Bernal, Luis; Bilbao, Luis

    2018-05-01

    From an apparatus previously designed for measuring the Doppler shift using a rotating mirror, an improved, versatile version was developed for speed of light demonstrations in a classroom or a teaching laboratory. By adding a second detector and adequate beam-splitter and mirrors, three different configurations are easily assembled. One configuration is used for time-of-flight measurements between a near and a far detector, allowing one to measure the speed of light provided that the path length between detectors is known. Another variation is the interferometric method obtained by superposing the far and near signals in such a way that a minimum of the combined signal is obtained when the time delay makes the signals arrive out of phase by π radians. Finally, the standard Doppler configuration allows the measurement of the frequency beat as a function of the rotation frequency. The main advantages of the apparatus are (a) the experimental setup is simple and completely accessible to undergraduate students, (b) the light is visible, students can see the rays, which, with the use of appropriate screens, can be blocked at any point along their paths, (c) the experiment can take place entirely within the teaching laboratory or demonstration room (using the interferometric method, the shortest distance to the far mirror was as small as 0.5 m), and (d) different configurations can be built, including some economical setups within the budget of teaching laboratories.

  17. Dispersion calculation method based on S-transform and coordinate rotation for Love channel waves with two components

    Science.gov (United States)

    Feng, Lei; Zhang, Yugui

    2017-08-01

    Dispersion analysis is an important part of in-seam seismic data processing, and the calculation accuracy of the dispersion curve directly influences pickup errors of channel wave travel time. To extract an accurate channel wave dispersion curve from in-seam seismic two-component signals, we proposed a time-frequency analysis method based on single-trace signal processing; in addition, we formulated a dispersion calculation equation, based on S-transform, with a freely adjusted filter window width. To unify the azimuth of seismic wave propagation received by a two-component geophone, the original in-seam seismic data undergoes coordinate rotation. The rotation angle can be calculated based on P-wave characteristics, with high energy in the wave propagation direction and weak energy in the vertical direction. With this angle acquisition, a two-component signal can be converted to horizontal and vertical directions. Because Love channel waves have a particle vibration track perpendicular to the wave propagation direction, the signal in the horizontal and vertical directions is mainly Love channel waves. More accurate dispersion characters of Love channel waves can be extracted after the coordinate rotation of two-component signals.

  18. The YvfTU Two-component System is involved in plcR expression in Bacillus cereus

    NARCIS (Netherlands)

    Brillard, Julien; Susanna, Kim; Michaud, Caroline; Dargaignaratz, Claire; Gohar, Michel; Nielsen-Leroux, Christina; Ramarao, Nalini; Kolsto, Anne-Brit; Nguyen-The, Christophe; Lereclus, Didier; Broussolle, Veronique

    2008-01-01

    Background: Most extracellular virulence factors produced by Bacillus cereus are regulated by the pleiotropic transcriptional activator PlcR. Among strains belonging to the B. cereus group, the plcR gene is always located in the vicinity of genes encoding the YvfTU two-component system. The putative

  19. A Conserved Two-Component Signal Transduction System Controls the Response to Phosphate Starvation in Bifidobacterium breve UCC2003.

    NARCIS (Netherlands)

    Alvarez-Martin, P.; Fernandez, M.; O'Connell-Motherway, M.; O'Connell, K.J.; Sauvageot, N.; Fitzgerald, G.F.; Macsharry, J.; Zomer, A.L.; Sinderen, D. van

    2012-01-01

    This work reports on the identification and molecular characterization of the two-component regulatory system (2CRS) PhoRP, which controls the response to inorganic phosphate (P(i)) starvation in Bifidobacterium breve UCC2003. The response regulator PhoP was shown to bind to the promoter region of

  20. Atom-number squeezing and bipartite entanglement of two-component Bose-Einstein condensates: analytical results

    Energy Technology Data Exchange (ETDEWEB)

    Jin, G R; Wang, X W; Li, D; Lu, Y W, E-mail: grjin@bjtu.edu.c [Department of Physics, Beijing Jiaotong University, Beijing 100044 (China)

    2010-02-28

    We investigate spin dynamics of a two-component Bose-Einstein condensate with weak Josephson coupling. Analytical expressions of atom-number squeezing and bipartite entanglement are presented for atom-atom repulsive interactions. For attractive interactions, there is no number squeezing; however, the squeezing parameter is still useful to recognize the appearance of Schroedinger's cat state.

  1. Anomalous Doppler effects in bulk phononic crystal

    International Nuclear Information System (INIS)

    Cai Feiyan; He Zhaojian; Zhang Anqi; Ding Yiqun; Liu Zhengyou

    2010-01-01

    Doppler effects in simple cubic phononic crystal are studied theoretically and numerically. In addition to observing Doppler shifts from a moving source's frequencies inside the gap, we find that Doppler shifts can be multi-order, anisotropic, and the dominant order of shift depends on the band index that the source's frequency is in.

  2. Collapse and revival of the Doppler-Rabi oscillations of a moving atom in a cavity

    International Nuclear Information System (INIS)

    Kozlovskii, A. V.

    2008-01-01

    Collapse and revival of the Doppler-Rabi oscillations of a two-level atom moving in a cavity electromagnetic field are analyzed. The coupled atom-field dynamics are predicted accurately by numerical calculation and approximately by using the stationary phase approximation combined with the Poisson summation formula. The collapse and revival patterns are shown to be qualitatively different in the cases of moving atom and atom at rest. In particular, quantum revivals of Doppler-Rabi oscillations occur with a period determined by the Doppler shift of the atomic transition frequency. This regime of Doppler-Rabi oscillations requires that the Rabi frequency and the Doppler shift satisfy the condition Ω R D . Under the inverse relation, the collapse- revival phenomenon generally does not occur. It is shown that even a small amount of atom-cavity detuning eliminates collapse-revival behavior. The analysis is performed for both coherent and thermal cavity fields

  3. Spatial weighting of Doppler reactivity feedback

    International Nuclear Information System (INIS)

    Carew, J.F.; Diamond, D.J.; Todosow, M.

    1977-12-01

    The spatial weighting of the local Doppler feedback implicit in the determination of the core Doppler feedback reactivity has been investigated. Using a detailed planar PDQ7-II PWR model with local fuel-temperature feedback, the core Doppler spatial weight factor, S, has been determined for various control patterns and power levels. Assuming power-squared weighting of the local Doppler feedback, a simple analytic expression for S has been derived and, based on comparison with the PDQ7-II results, provides a convenient and accurate representation of the Doppler spatial weight factor. The sensitivity of these results to variations in the fuel rod heat transfer coefficients, fuel loading and the magnitude of the Doppler coefficient has also been evaluated. The dependence of the local Doppler coefficient on moderator temperature, boron concentration and control rod density has been determined and found to be weak. Selected comparisons with vendor analyses have been made and indicate general agreement

  4. A comparison of two-component and quadratic models to assess survival of irradiated stage-7 oocytes of Drosophila melanogaster

    International Nuclear Information System (INIS)

    Peres, C.A.; Koo, J.O.

    1981-01-01

    In this paper, the quadratic model to analyse data of this kind, i.e. S/S 0 = exp(-αD-bD 2 ), where S and Ssub(o) are defined as before is proposed is shown that the same biological interpretation can be given to the parameters α and A and to the parameters β and B. Furthermore it is shown that the quadratic model involves one probabilistic stage more than the two-component model, and therefore the quadratic model would perhaps be more appropriate as a dose-response model for survival of irradiated stage-7 oocytes of Drosophila melanogaster. In order to apply these results, the data presented by Sankaranarayanan and Sankaranarayanan and Volkers are reanalysed using the quadratic model. It is shown that the quadratic model fits better than the two-component model to the data in most situations. (orig./AJ)

  5. Effects of non-uniform temperature gradients on surface tension driven two component magneto convection in a porous- fluid system

    Science.gov (United States)

    Manjunatha, N.; Sumithra, R.

    2018-04-01

    The problem of surface tension driven two component magnetoconvection is investigated in a Porous-Fluid system, consisting of anincompressible two component electrically conducting fluid saturatedporous layer above which lies a layer of the same fluid in the presence of a uniform vertical magnetic field. The lower boundary of the porous layeris rigid and the upper boundary of the fluid layer is free with surfacetension effects depending on both temperature and concentration, boththese boundaries are insulating to heat and mass. At the interface thevelocity, shear and normal stress, heat and heat flux, mass and mass fluxare assumed to be continuous suitable for Darcy-Brinkman model. Theeigenvalue problem is solved in linear, parabolic and inverted parabolictemperature profiles and the corresponding Thermal Marangoni Numberis obtained for different important physical parameters.

  6. Recovering four-component solutions by the inverse transformation of the infinite-order two-component wave functions

    International Nuclear Information System (INIS)

    Barysz, Maria; Mentel, Lukasz; Leszczynski, Jerzy

    2009-01-01

    The two-component Hamiltonian of the infinite-order two-component (IOTC) theory is obtained by a unitary block-diagonalizing transformation of the Dirac-Hamiltonian. Once the IOTC spin orbitals are calculated, they can be back transformed into four-component solutions. The transformed four component solutions are then used to evaluate different moments of the electron density distribution. This formally exact method may, however, suffer from certain approximations involved in its numerical implementation. As shown by the present study, with sufficiently large basis set of Gaussian functions, the Dirac values of these moments are fully recovered in spite of using the approximate identity resolution into eigenvectors of the p 2 operator.

  7. Rayleigh-Taylor instability and mushroom-pattern formation in a two-component Bose-Einstein condensate

    International Nuclear Information System (INIS)

    Sasaki, Kazuki; Suzuki, Naoya; Saito, Hiroki; Akamatsu, Daisuke

    2009-01-01

    The Rayleigh-Taylor instability at the interface in an immiscible two-component Bose-Einstein condensate is investigated using the mean field and Bogoliubov theories. Rayleigh-Taylor fingers are found to grow from the interface and mushroom patterns are formed. Quantized vortex rings and vortex lines are then generated around the mushrooms. The Rayleigh-Taylor instability and mushroom-pattern formation can be observed in a trapped system.

  8. Investigation of low-latitude hydrogen emission in terms of a two-component interstellar gas model

    International Nuclear Information System (INIS)

    Baker, P.L.; Burton, W.B.

    1975-01-01

    The high-resolution 21-cm hydrogen line observations at low galactic latitude of Burton and Verschuur have been analyzed to determine the large-scale distribution of galactic hydrogen. The distribution parameters are found by model fitting. Optical depth affects have been computed using a two-component gas model. Analysis shows that a multiphase description of the medium is essential to the interpretation of low-latitude emission observations. Where possible, the number of free parameters in the gas model has been reduced. Calculations were performed for a one-component, uniform spin temperature, gas model in order to show the systematic departures between this model and the data caused by the incorrect treatment of the optical depth effect. In the two-component gas, radiative transfer is treated by a Monte Carlo calculation since the opacity of the gas arises in a randomly distributed, cold, optically thick, low velocity-dispersion, cloud medium. The emission arises in both the cloud medium and a smoothly distributed, optically thin, high velocity-dispersion, intercloud medium. The synthetic profiles computed from the two-component model reproduce both the large-scale trends of the observed emission profiles and the magnitude of the small-scale emission irregularities. The analysis permits the determination of values for []he thickness of the galactic disk between half density points, the total observed neutral hydrogen mass of the Galaxy, and the central number density of the intercloud atoms. In addition, the analysis is sensitive to the size of clouds contributing to the observations. Computations also show that synthetic emission profiles based on the two-component model display both the zero-velocity and high-velocity ridges, indicative of optical thinness on a large scale, in spite of the presence of optically thick gas

  9. Umbilical artery doppler abnormalities and associated factors in ...

    African Journals Online (AJOL)

    Critically ill patients and those in active phase of labour or premature rupture of membranes were excluded. Results: The overall prevalence of UA Doppler abnormalities was 31.6%. High RI, high S/D ratio, AEDV and RF were found in 25.8%, 31.6%, 7.7% and 4.5% of the population respectively. Key factors associated with ...

  10. Evaluation of the activity of synovitis in patients with rheumatoid arthritis: Value of power Doppler ultrasonography

    International Nuclear Information System (INIS)

    Ahn, Joong Mo; Lim, Hyo Keun; Kim, Seung Hoon; Kim, Sung Hyun; Koh, Eun Mi; Kim, Jin Seok; Cha, Hoon Suk

    2001-01-01

    To correlate the grades on power Doppler ultrasonography with clinical disease activity indices and acute phase reactant values for assessing the activity of synovitis in patients with rheumatoid arthritis. Twenty patients with rheumatoid arthritis diagnosed on the basis of American College of power Doppler ultrasonography. Two experienced radiologists evaluated, in consensus, the power Doppler signals as follows: grade I=no flow or minimal flow, grade 2=mild flow, grade 3=moderate flow and grade 4= marked flow. The clinical disease activity indices consisted of the counts of tender joints and swollen joints, patient's assessment of pain, patient's global assessment of disease activity, physician's globe assessment of disease activity and patient's assessment of physical function. Acute-phase reactants included CRP and ESR. The grades on power Doppler ultrasonography were correlated with clinical disease activity indices as well as acute-phases reactant values by a use of Spearman rank correlation coefficient. The grades on power Doppler ultrasonography showed a statistically significant correlation with tender joint count (rs=.835; p<.05), swollen joint count (rs=.833; p<.05), physician's global assessment of disease activity (rs=.857; p<.05), CRP (rs=.838; P<.05) and ESR (rs=.838; p<.05). The power Doppler ultrasonography is an useful diagnostic modality for assessing the activity of synovitis in patients with rheumatoid arthritis.

  11. Doppler tomography in fusion plasmas and astrophysics

    DEFF Research Database (Denmark)

    Salewski, Mirko; Geiger, B.; Heidbrink, W. W.

    2015-01-01

    Doppler tomography is a well-known method in astrophysics to image the accretion flow, often in the shape of thin discs, in compact binary stars. As accretion discs rotate, all emitted line radiation is Doppler-shifted. In fast-ion Dα (FIDA) spectroscopy measurements in magnetically confined plasma......, the Dα-photons are likewise Doppler-shifted ultimately due to gyration of the fast ions. In either case, spectra of Doppler-shifted line emission are sensitive to the velocity distribution of the emitters. Astrophysical Doppler tomography has lead to images of accretion discs of binaries revealing bright...... and limits, analogies and differences in astrophysical and fusion plasma Doppler tomography and what can be learned by comparison of these applications....

  12. Measurement of ventricular function using Doppler ultrasound

    International Nuclear Information System (INIS)

    Teague, S.M.

    1986-01-01

    Doppler has wide application in the evaluation of valvular heart disease. The need to know ventricular function is a much more common reason for an echocardiographic evaluation. Interestingly, Doppler examinations can assess ventricular function from many perspectives. Description of ventricular function entails measurement of the timing, rate and volume of ventricular filling and ejection. Doppler ultrasound examination reveals all of these aspects of ventricular function noninvasively, simply, and without great expense or radiation exposure, as described in this chapter

  13. A new pair of hard-soft plastic combination for precision manufacturing of two component plastic parts

    DEFF Research Database (Denmark)

    Islam, Aminul; Hansen, Hans Nørgaard; Marhöfer, David Maximilian

    2011-01-01

    the pressure developed inside the socket house and finally could detect the leak of the fluid due to the sealing ring leakage. All the test procedures and results presented in this paper can be a valuable source of information for researchers and scientists who work with two component micro injection moulding....... sequential and simultaneous injection of two materials and afterwards by using a precision tensile testing machine. To characterize the sealing properties of the sealing ring material, a sealing test device was developed. It could provide hydraulic pressure inside the socket house and precisely detect...

  14. Doppler ultrasound scan during normal gestation: umbilical circulation

    International Nuclear Information System (INIS)

    Ruiz, T.; Sabate, J.; Martinez-Benavides, M. M.; Sanchez-Ramos, J.

    2002-01-01

    To determine normal umbilical circulation patterns by means of Doppler ultrasound scan in a healthy gestating population without risk factors and with normal perinatal results, and to evaluate any occurring modifications relative to gestational age by obtaining records kept during pregnancy. One hundred and sixteen pregnant women carrying a single fetus have been studied. These women had no risk factors, with both clinical and analytical controls, as well as ultrasound scans, all being normal. There were performed a total of 193 Doppler ultrasound scans between weeks 15 and 41 of gestation, with blood-flow analysis in the arteries and vein of the umbilical cord. The obtained information was correlated with parameters that evaluate fetal well-being (fetal monitoring and/or oxytocin test) and perinatal result (delivery type, birth weight, Apgar score). Statistical analysis was performed with the programs SPSS 6.0.1 for Windows and EPIINFO 6.0.4. With pulsed Doppler, the umbilical artery in all cases demonstrated a biphasic morphology with systolic and diastolic components and without retrograde blood flow. As the gestation period increased, there was observed a progressive decrease in resistance along with an increase in blood-flow velocity during the diastolic phase. The Doppler ultrasound scan is a non-invasive method that permits the hemodynamic study of umbilical blood circulation. A knowledge of normal blood-flow signal morphology, as well as of the normal values for Doppler indices in relation to gestational age would permit us to utilize this method in high-risk pregnancies. (Author) 30 refs

  15. Direct Doppler auscultation of the carotid arteries

    International Nuclear Information System (INIS)

    Nix, L.

    1984-01-01

    The results of the carotid Doppler examinations and contrast arteriograms are presented. The overall sensitivity of the carotid Doppler examinations in detecting severe stenosis or occlusion of the carotid artery was 92%. The Doppler studies correctly differentiated these two conditions in 84% of the diseased vessels. In carotid arteries with stenosis greater than or equal to 50%, the sensitivity of the Doppler examinations was 90%, and these studies suggested stenosis in all but two of the 36 abnormal examinations. In two patent carotids with greater than 90% stenosis, a signal could not be elicited, presumably because of the low blood flow through the severely stenotic segment

  16. Spin-orbit coupling calculations with the two-component normalized elimination of the small component method

    Science.gov (United States)

    Filatov, Michael; Zou, Wenli; Cremer, Dieter

    2013-07-01

    A new algorithm for the two-component Normalized Elimination of the Small Component (2cNESC) method is presented and tested in the calculation of spin-orbit (SO) splittings for a series of heavy atoms and their molecules. The 2cNESC is a Dirac-exact method that employs the exact two-component one-electron Hamiltonian and thus leads to exact Dirac SO splittings for one-electron atoms. For many-electron atoms and molecules, the effect of the two-electron SO interaction is modeled by a screened nucleus potential using effective nuclear charges as proposed by Boettger [Phys. Rev. B 62, 7809 (2000), 10.1103/PhysRevB.62.7809]. The use of the screened nucleus potential for the two-electron SO interaction leads to accurate spinor energy splittings, for which the deviations from the accurate Dirac Fock-Coulomb values are on the average far below the deviations observed for other effective one-electron SO operators. For hydrogen halides HX (X = F, Cl, Br, I, At, and Uus) and mercury dihalides HgX2 (X = F, Cl, Br, I) trends in spinor energies and SO splittings as obtained with the 2cNESC method are analyzed and discussed on the basis of coupling schemes and the electronegativity of X.

  17. Lactoferricin B Inhibits the Phosphorylation of the Two-Component System Response Regulators BasR and CreB*

    Science.gov (United States)

    Ho, Yu-Hsuan; Sung, Tzu-Cheng; Chen, Chien-Sheng

    2012-01-01

    Natural antimicrobial peptides provide fundamental protection for multicellular organisms from microbes, such as Lactoferricin B (Lfcin B). Many studies have shown that Lfcin B penetrates the cell membrane and has intracellular activities. To elucidate the intracellular behavior of Lfcin B, we first used Escherichia coli K12 proteome chips to identify the intracellular targets of Lfcin B. The results showed that Lfcin B binds to two response regulators, BasR and CreB, of the two-component system. For further analysis, we conducted several in vitro and in vivo experiments and utilized bioinformatics methods. The electrophoretic mobility shift assays and kinase assays indicate that Lfcin B inhibits the phosphorylation of the response regulators (BasR and CreB) and their cognate sensor kinases (BasS and CreC). Antibacterial assays showed that Lfcin B reduced E. coli's tolerance to environmental stimuli, such as excessive ferric ions and minimal medium conditions. This is the first study to show that an antimicrobial peptide inhibits the growth of bacteria by influencing the phosphorylation of a two-component system directly. PMID:22138548

  18. Lactoferricin B inhibits the phosphorylation of the two-component system response regulators BasR and CreB.

    Science.gov (United States)

    Ho, Yu-Hsuan; Sung, Tzu-Cheng; Chen, Chien-Sheng

    2012-04-01

    Natural antimicrobial peptides provide fundamental protection for multicellular organisms from microbes, such as Lactoferricin B (Lfcin B). Many studies have shown that Lfcin B penetrates the cell membrane and has intracellular activities. To elucidate the intracellular behavior of Lfcin B, we first used Escherichia coli K12 proteome chips to identify the intracellular targets of Lfcin B. The results showed that Lfcin B binds to two response regulators, BasR and CreB, of the two-component system. For further analysis, we conducted several in vitro and in vivo experiments and utilized bioinformatics methods. The electrophoretic mobility shift assays and kinase assays indicate that Lfcin B inhibits the phosphorylation of the response regulators (BasR and CreB) and their cognate sensor kinases (BasS and CreC). Antibacterial assays showed that Lfcin B reduced E. coli's tolerance to environmental stimuli, such as excessive ferric ions and minimal medium conditions. This is the first study to show that an antimicrobial peptide inhibits the growth of bacteria by influencing the phosphorylation of a two-component system directly.

  19. How insects overcome two-component plant chemical defence: plant β-glucosidases as the main target for herbivore adaptation.

    Science.gov (United States)

    Pentzold, Stefan; Zagrobelny, Mika; Rook, Fred; Bak, Søren

    2014-08-01

    Insect herbivory is often restricted by glucosylated plant chemical defence compounds that are activated by plant β-glucosidases to release toxic aglucones upon plant tissue damage. Such two-component plant defences are widespread in the plant kingdom and examples of these classes of compounds are alkaloid, benzoxazinoid, cyanogenic and iridoid glucosides as well as glucosinolates and salicinoids. Conversely, many insects have evolved a diversity of counteradaptations to overcome this type of constitutive chemical defence. Here we discuss that such counter-adaptations occur at different time points, before and during feeding as well as during digestion, and at several levels such as the insects’ feeding behaviour, physiology and metabolism. Insect adaptations frequently circumvent or counteract the activity of the plant β-glucosidases, bioactivating enzymes that are a key element in the plant’s two-component chemical defence. These adaptations include host plant choice, non-disruptive feeding guilds and various physiological adaptations as well as metabolic enzymatic strategies of the insect’s digestive system. Furthermore, insect adaptations often act in combination, may exist in both generalists and specialists, and can act on different classes of defence compounds. We discuss how generalist and specialist insects appear to differ in their ability to use these different types of adaptations: in generalists, adaptations are often inducible, whereas in specialists they are often constitutive. Future studies are suggested to investigate in detail how insect adaptations act in combination to overcome plant chemical defences and to allow ecologically relevant conclusions.

  20. Many-body physics in two-component Bose–Einstein condensates in a cavity: fragmented superradiance and polarization

    Science.gov (United States)

    Lode, Axel U. J.; Diorico, Fritz S.; Wu, RuGway; Molignini, Paolo; Papariello, Luca; Lin, Rui; Lévêque, Camille; Exl, Lukas; Tsatsos, Marios C.; Chitra, R.; Mauser, Norbert J.

    2018-05-01

    We consider laser-pumped one-dimensional two-component bosons in a parabolic trap embedded in a high-finesse optical cavity. Above a threshold pump power, the photons that populate the cavity modify the effective atom trap and mediate a coupling between the two components of the Bose–Einstein condensate. We calculate the ground state of the laser-pumped system and find different stages of self-organization depending on the power of the laser. The modified potential and the laser-mediated coupling between the atomic components give rise to rich many-body physics: an increase of the pump power triggers a self-organization of the atoms while an even larger pump power causes correlations between the self-organized atoms—the BEC becomes fragmented and the reduced density matrix acquires multiple macroscopic eigenvalues. In this fragmented superradiant state, the atoms can no longer be described as two-level systems and the mapping of the system to the Dicke model breaks down.

  1. The Coincident Coherence of Extreme Doppler Velocity Events with p-mode Patches in the Solar Photosphere.

    Science.gov (United States)

    McClure, Rachel Lee

    2018-06-01

    Observations of the solar photosphere show many spatially compact Doppler velocity events with short life spans and extreme values. In the IMaX spectropolarimetric inversion data of the first flight of the SUNRISE balloon in 2009 these striking flashes in the intergranule lanes and complementary outstanding values in the centers of granules have line of sight Doppler velocity values in excess of 4 sigma from the mean. We conclude that values outside 4 sigma are a result from the superposition of the granulation flows and the p-modes.To determine how granulation and p-modes contribute to these outstanding Doppler events, I separate the two components using the Fast Fourier Transform. I produce the power spectrum of the spatial wave frequencies and their corresponding frequency in time for each image, and create a k-omega filter to separate the two components. Using the filtered data, test the hypothesis that extreme events occur because of strict superposition between the p-mode Doppler velocities and the granular velocities. I compare event counts from the observational data to those produced by random superposition of the two flow components and find that the observational event counts are consistent with the model event counts in the limit of small number statistics. Poisson count probabilities of event numbers observed are consistent with expected model count probability distributions.

  2. Ground-state and rotational properties of a two-component Bose–Einstein condensate in a harmonic plus quartic trap

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Guang-Ping [Key Laboratory of Time and Frequency Primary Standards, National Time Service Center, Chinese Academy of Sciences, Xi' an 710600 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Zhang, Zhi-Yuan [The School of Physics and Mech-tronic Engineering, Sichuan University of Art and Science, DaZhou 635000 (China); Dong, Biao [Key Laboratory of Time and Frequency Primary Standards, National Time Service Center, Chinese Academy of Sciences, Xi' an 710600 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Wang, Lin-Xue [College of Physics and Electronic Engineering, Northwest Normal University, Lanzhou 730070 (China); Zhang, Xiao-Fei, E-mail: xfzhang@ntsc.ac.cn [Key Laboratory of Time and Frequency Primary Standards, National Time Service Center, Chinese Academy of Sciences, Xi' an 710600 (China); Zhang, Shou-Gang, E-mail: szhang@ntsc.ac.cn [Key Laboratory of Time and Frequency Primary Standards, National Time Service Center, Chinese Academy of Sciences, Xi' an 710600 (China)

    2015-10-02

    We consider a two-component Bose–Einstein condensate under extreme elongation in a harmonic plus quartic trap. The ground-state and rotational properties of such a system are numerically studied as a function of intra- and inter-component contact interactions, and of the rotational frequency. For the nonrotational case, we obtain the exact phase diagram showing the ground-state density distributions as contact-interactions varied. For both slowly and ultrarapidly rotational cases, we demonstrate that the vortex configurations depend strongly on the relative strength of the contact interactions, as well as on the rotational frequency. The controllable system may be used to investigate the interplay of interaction and rotation, and to explore more exotic quantum phases. - Highlights: • Quartic trap extends the parameter space to a fast rotating region. • Different ground state density distributions and novel vortex structures are obtained within the full parameter space. • Effects of the contact interactions and rotation are discussed in detail.

  3. Ground-state and rotational properties of a two-component Bose–Einstein condensate in a harmonic plus quartic trap

    International Nuclear Information System (INIS)

    Chen, Guang-Ping; Zhang, Zhi-Yuan; Dong, Biao; Wang, Lin-Xue; Zhang, Xiao-Fei; Zhang, Shou-Gang

    2015-01-01

    We consider a two-component Bose–Einstein condensate under extreme elongation in a harmonic plus quartic trap. The ground-state and rotational properties of such a system are numerically studied as a function of intra- and inter-component contact interactions, and of the rotational frequency. For the nonrotational case, we obtain the exact phase diagram showing the ground-state density distributions as contact-interactions varied. For both slowly and ultrarapidly rotational cases, we demonstrate that the vortex configurations depend strongly on the relative strength of the contact interactions, as well as on the rotational frequency. The controllable system may be used to investigate the interplay of interaction and rotation, and to explore more exotic quantum phases. - Highlights: • Quartic trap extends the parameter space to a fast rotating region. • Different ground state density distributions and novel vortex structures are obtained within the full parameter space. • Effects of the contact interactions and rotation are discussed in detail

  4. Performance evaluation of a thermal Doppler Michelson interferometer system.

    Science.gov (United States)

    Mani, Reza; Dobbie, Steven; Scott, Alan; Shepherd, Gordon; Gault, William; Brown, Stephen

    2005-11-20

    The thermal Doppler Michelson interferometer is the primary element of a proposed limb-viewing satellite instrument called SWIFT (Stratospheric Wind Interferometer for Transport studies). SWIFT is intended to measure stratospheric wind velocities in the altitude range of 15-45 km. SWIFT also uses narrowband tandem etalon filters made of germanium to select a line out of the thermal spectrum. The instrument uses the same technique of phase-stepping interferometry employed by the Wind Imaging Interferometer onboard the Upper Atmosphere Research Satellite. A thermal emission line of ozone near 9 microm is used to detect the Doppler shift due to winds. A test bed was set up for this instrument that included the Michelson interferometer and the etalon filters. For the test bed work, we investigate the behavior of individual components and their combination and report the results.

  5. A Doppler Radar System for Sensing Physiological Parameters in Walking and Standing Positions

    Directory of Open Access Journals (Sweden)

    Malikeh Pour Ebrahim

    2017-03-01

    Full Text Available Doppler radar can be implemented for sensing physiological parameters wirelessly at a distance. Detecting respiration rate, an important human body parameter, is essential in a range of applications like emergency and military healthcare environments, and Doppler radar records actual chest motion. One challenge in using Doppler radar is being able to monitor several patients simultaneously and in different situations like standing, walking, or lying. This paper presents a complete transmitter-receiver Doppler radar system, which uses a 4 GHz continuous wave radar signal transmission and receiving system, to extract base-band data from a phase-shifted signal. This work reports experimental evaluations of the system for one and two subjects in various standing and walking positions. It provides a detailed signal analysis of various breathing rates of these two subjects simultaneously. These results will be useful in future medical monitoring applications.

  6. Radar Doppler Processing with Nonuniform Sampling.

    Energy Technology Data Exchange (ETDEWEB)

    Doerry, Armin W. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-07-01

    Conventional signal processing to estimate radar Doppler frequency often assumes uniform pulse/sample spacing. This is for the convenience of t he processing. More recent performance enhancements in processor capability allow optimally processing nonuniform pulse/sample spacing, thereby overcoming some of the baggage that attends uniform sampling, such as Doppler ambiguity and SNR losses due to sidelobe control measures.

  7. Two-phase flow models

    International Nuclear Information System (INIS)

    Delaje, Dzh.

    1984-01-01

    General hypothesis used to simplify the equations, describing two-phase flows, are considered. Two-component and one-component models of two-phase flow, as well as Zuber and Findlay model for actual volumetric steam content, and Wallis model, describing the given phase rates, are presented. The conclusion is made, that the two-component model, in which values averaged in time are included, is applicable for the solving of three-dimensional tasks for unsteady two-phase flow. At the same time, using the two-component model, including values, averaged in space only one-dimensional tasks for unsteady two-phase flow can be solved

  8. Estimating the Doppler centroid of SAR data

    DEFF Research Database (Denmark)

    Madsen, Søren Nørvang

    1989-01-01

    attractive properties. An evaluation based on an existing SEASAT processor is reported. The time-domain algorithms are shown to be extremely efficient with respect to requirements on calculations and memory, and hence they are well suited to real-time systems where the Doppler estimation is based on raw SAR......After reviewing frequency-domain techniques for estimating the Doppler centroid of synthetic-aperture radar (SAR) data, the author describes a time-domain method and highlights its advantages. In particular, a nonlinear time-domain algorithm called the sign-Doppler estimator (SDE) is shown to have...... data. For offline processors where the Doppler estimation is performed on processed data, which removes the problem of partial coverage of bright targets, the ΔE estimator and the CDE (correlation Doppler estimator) algorithm give similar performance. However, for nonhomogeneous scenes it is found...

  9. Influence of electron-phonon interaction on soliton mediated spin-charge conversion effects in two-component polymer model

    International Nuclear Information System (INIS)

    Sergeenkov, S.; Moraes, F.; Furtado, C.; Araujo-Moreira, F.M.

    2010-01-01

    By mapping a Hubbard-like model describing a two-component polymer in the presence of strong enough electron-phonon interactions (κ) onto the system of two coupled nonlinear Schroedinger equations with U(2) symmetry group, some nontrivial correlations between topological solitons mediated charge Q and spin S degrees of freedom are obtained. Namely, in addition to a charge fractionalization and reentrant like behavior of both Q(κ) and S(κ), the model also predicts a decrease of soliton velocity with κ as well as spin-charge conversion effects which manifest themselves through an explicit S(Q,Ω) dependence (with Ω being a mixing angle between spin-up and spin-down electron amplitudes). A possibility to observe the predicted effects in low-dimensional systems with charge and spin soliton carriers is discussed.

  10. Droplet size and velocity at the exit of a nozzle with two-component near critical and critical flow

    International Nuclear Information System (INIS)

    Lemonnier, H.; Camelo-Cavalcanti, E.S.

    1993-01-01

    Two-component critical flow modelling is an important issue for safety studies of various hazardous industrial activities. When the flow quality is high, the critical flow rate prediction is sensitive to the modelling of gas droplet mixture interfacial area. In order to improve the description of these flows, experiments were conducted with air-water flows in converging nozzles. The pressure was 2 and 4 bar and the gas mass quality ranged between 100% and 20%. The droplets size and velocity have been measured close to the outlet section of a nozzle with a 10 mm diameter throat. Subcritical and critical conditions were observed. These data are compared with the predictions of a critical flow model which includes an interfacial area model based on the classical ideas of Hinze and Kolmogorov. (authors). 9 figs., 12 refs

  11. Simple Analytical Forms of the Perpendicular Diffusion Coefficient for Two-component Turbulence. III. Damping Model of Dynamical Turbulence

    Energy Technology Data Exchange (ETDEWEB)

    Gammon, M.; Shalchi, A., E-mail: andreasm4@yahoo.com [Department of Physics and Astronomy, University of Manitoba, Winnipeg, Manitoba R3T 2N2 (Canada)

    2017-10-01

    In several astrophysical applications one needs analytical forms of cosmic-ray diffusion parameters. Some examples are studies of diffusive shock acceleration and solar modulation. In the current article we explore perpendicular diffusion based on the unified nonlinear transport theory. While we focused on magnetostatic turbulence in Paper I, we included the effect of dynamical turbulence in Paper II of the series. In the latter paper we assumed that the temporal correlation time does not depend on the wavenumber. More realistic models have been proposed in the past, such as the so-called damping model of dynamical turbulence. In the present paper we derive analytical forms for the perpendicular diffusion coefficient of energetic particles in two-component turbulence for this type of time-dependent turbulence. We present new formulas for the perpendicular diffusion coefficient and we derive a condition for which the magnetostatic result is recovered.

  12. ResDE Two-Component Regulatory System Mediates Oxygen Limitation-Induced Biofilm Formation by Bacillus amyloliquefaciens SQR9.

    Science.gov (United States)

    Zhou, Xuan; Zhang, Nan; Xia, Liming; Li, Qing; Shao, Jiahui; Shen, Qirong; Zhang, Ruifu

    2018-04-15

    Efficient biofilm formation and root colonization capabilities facilitate the ability of beneficial plant rhizobacteria to promote plant growth and antagonize soilborne pathogens. Biofilm formation by plant-beneficial Bacillus strains is triggered by environmental cues, including oxygen deficiency, but the pathways that sense these environmental signals and regulate biofilm formation have not been thoroughly elucidated. In this study, we showed that the ResDE two-component regulatory system in the plant growth-promoting rhizobacterium Bacillus amyloliquefaciens strain SQR9 senses the oxygen deficiency signal and regulates biofilm formation. ResE is activated by sensing the oxygen limitation-induced reduction of the NAD + /NADH pool through its PAS domain, stimulating its kinase activity, and resulting in the transfer of a phosphoryl group to ResD. The phosphorylated ResD directly binds to the promoter regions of the qoxABCD and ctaCDEF operons to improve the biosynthesis of terminal oxidases, which can interact with KinB to activate biofilm formation. These results not only revealed the novel regulatory function of the ResDE two-component system but also contributed to the understanding of the complicated regulatory network governing Bacillus biofilm formation. This research may help to enhance the root colonization and the plant-beneficial efficiency of SQR9 and other Bacillus rhizobacteria used in agriculture. IMPORTANCE Bacillus spp. are widely used as bioinoculants for plant growth promotion and disease suppression. The exertion of their plant-beneficial functions is largely dependent on their root colonization, which is closely related to their biofilm formation capabilities. On the other hand, Bacillus is the model bacterium for biofilm study, and the process and molecular network of biofilm formation are well characterized (B. Mielich-Süss and D. Lopez, Environ Microbiol 17:555-565, 2015, https://doi.org/10.1111/1462-2920.12527; L. S. Cairns, L. Hobley, and

  13. The two-component system VicRK regulates functions associated with Streptococcus mutans resistance to complement immunity.

    Science.gov (United States)

    Alves, Livia A; Harth-Chu, Erika N; Palma, Thais H; Stipp, Rafael N; Mariano, Flávia S; Höfling, José F; Abranches, Jacqueline; Mattos-Graner, Renata O

    2017-10-01

    Streptococcus mutans, a dental caries pathogen, can promote systemic infections upon reaching the bloodstream. The two-component system (TCS) VicRK Sm of S. mutans regulates the synthesis of and interaction with sucrose-derived exopolysaccharides (EPS), processes associated with oral and systemic virulence. In this study, we investigated the mechanisms by which VicRK Sm affects S. mutans susceptibility to blood-mediated immunity. Compared with parent strain UA159, the vicK Sm isogenic mutant (UAvic) showed reduced susceptibility to deposition of C3b of complement, low binding to serum immunoglobulin G (IgG), and low frequency of C3b/IgG-mediated opsonophagocytosis by polymorphonuclear cells in a sucrose-independent way (Pmutans employs mechanisms of complement evasion through peptidases, which are controlled by VicRK Sm. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  14. Genome-wide DNA binding pattern of two-component system response regulator RhpR in Pseudomonas syringae

    Directory of Open Access Journals (Sweden)

    Tianhong Zhou

    2015-06-01

    Full Text Available Although Pseudomonas syringae uses the two-component system RhpRS to modulate the expression of type III secretion system (T3SS genes and pathogenicity, the molecular mechanisms and the regulon of RhpRS have yet to be fully demonstrated. We have performed a genome-wide analysis of RhpR binding to DNA prepared from P. syringae pv. phaseolicola in order to identify candidate direct targets of RhpR-mediated transcriptional regulation, as described in our recent article [1]. The data are available from NCBI Gene Expression Omnibus (GEO with the accession number GSE58533. Here we describe the detailed methods and data analyses of our RhpR ChIP-seq dataset.

  15. Dynamics of trapped two-component Fermi gas: Temperature dependence of the transition from collisionless to collisional regime

    International Nuclear Information System (INIS)

    Toschi, F.; Vignolo, P.; Tosi, M.P.; Succi, S.

    2003-01-01

    We develop a numerical method to study the dynamics of a two-component atomic Fermi gas trapped inside a harmonic potential at temperature T well below the Fermi temperature T F . We examine the transition from the collisionless to the collisional regime down to T=0.2 T F and find a good qualitative agreement with the experiments of B. DeMarco and D.S. Jin [Phys. Rev. Lett. 88, 040405 (2002)]. We demonstrate a twofold role of temperature on the collision rate and on the efficiency of collisions. In particular, we observe a hitherto unreported effect, namely, the transition to hydrodynamic behavior is shifted towards lower collision rates as temperature decreases

  16. Three-body recombination of two-component cold atomic gases into deep dimers in an optical model

    DEFF Research Database (Denmark)

    Mikkelsen, Mathias; Jensen, A. S.; Fedorov, D. V.

    2015-01-01

    to the decay rate or recombination probability of the three-body system. The method is formulated in details and the relevant qualitative features are discussed as functions of scattering lengths and masses. We use zero-range model in analyses of recent recombination data. The dominating scattering length......We consider three-body recombination into deep dimers in a mass-imbalanced two-component atomic gas. We use an optical model where a phenomenological imaginary potential is added to the lowest adiabatic hyper-spherical potential. The consequent imaginary part of the energy eigenvalue corresponds...... is usually related to the non-equal two-body systems. We account for temperature smearing which tends to wipe out the higher-lying Efimov peaks. The range and the strength of the imaginary potential determine positions and shapes of the Efimov peaks as well as the absolute value of the recombination rate...

  17. Color doppler sonography in thickened gallbladder wall

    International Nuclear Information System (INIS)

    Han, Sang Suk; Choi, Seok Jin; Seo, Chang Hae; Eun, Choong Ki

    1996-01-01

    The thickening of the gallbladder wall is a valuable finding for the diagnosis of cholecystitis, but may be seen in non-cholecystic disease as well as in acute or chronic cholecystitis. The purpose of this study is to determine the value of color Doppler sonography in differentiating the causes of thickened gallbladder wall. Ninety eight patients with thickened gallbladder wall(more than 3mm) which was not due to gallbladder cancer were prospectively evaluated with color Doppler sonography. Sixty-six cases, confirmed by pathologic reports and clinical records, were analyzed for correlation between thickened gallbladder wall and color flow signal according to the underlying causes. Of the 66 patients, 28 cases were cholecystitis and 38 cases had non-cholecystic causes such as liver cirrhosis, ascites, hepatitis, pancreatitis, renal failure, and hypoalbuminemia. Of the 28 patients with cholecystitis(12 acute, 16 chronic), 23(82%) had color Doppler flow signals in the thickened gallbladder wall. Of the 38 patients with non-cholecystic causes, eight(21%) had color Doppler flow signals. There was a statistically significant difference of color Doppler flow signals between the cholecystitis and non-cholecystic groups(p=0.0001). No significant difference of color Doppler flow signals was found between cases of acute and chronic cholecystitis. Of the 23 patients with color Doppler flow signals in 28 cases of cholecystitis, 18(78.3%) showed a linear pattern and five(21.7%) showed a spotty pattern. Of the eight patients with color Doppler flow signals in the 38 non-cholecystic cases, four(50%) showed a linear pattern and four(50%) showed a spotty pattern. In cholecystitis, a linear color Doppler flow signal pattern is a much more frequent finding than a spotty pattern. Color Doppler sonography is a useful and adequate method for determining whether a thickened gallbladder wall is the result of cholecystitis or has non-cholecystic causes

  18. Characterization of virulence factor regulation by SrrAB, a two-component system in Staphylococcus aureus.

    Science.gov (United States)

    Pragman, Alexa A; Yarwood, Jeremy M; Tripp, Timothy J; Schlievert, Patrick M

    2004-04-01

    Workers in our laboratory have previously identified the staphylococcal respiratory response AB (SrrAB), a Staphylococcus aureus two-component system that acts in the global regulation of virulence factors. This system down-regulates production of agr RNAIII, protein A, and toxic shock syndrome toxin 1 (TSST-1), particularly under low-oxygen conditions. In this study we investigated the localization and membrane orientation of SrrA and SrrB, transcription of the srrAB operon, the DNA-binding properties of SrrA, and the effect of SrrAB expression on S. aureus virulence. We found that SrrA is localized to the S. aureus cytoplasm, while SrrB is localized to the membrane and is properly oriented to function as a histidine kinase. srrAB has one transcriptional start site which results in either an srrA transcript or a full-length srrAB transcript; srrB must be cotranscribed with srrA. Gel shift assays of the agr P2, agr P3, protein A (spa), TSST-1 (tst), and srr promoters revealed SrrA binding at each of these promoters. Analysis of SrrAB-overexpressing strains by using the rabbit model of bacterial endocarditis demonstrated that overexpression of SrrAB decreased the virulence of the organisms compared to the virulence of isogenic strains that do not overexpress SrrAB. We concluded that SrrAB is properly localized and oriented to function as a two-component system. Overexpression of SrrAB, which represses agr RNAIII, TSST-1, and protein A in vitro, decreases virulence in the rabbit endocarditis model. Repression of these virulence factors is likely due to a direct interaction between SrrA and the agr, tst, and spa promoters.

  19. Thusin, a novel two-component lantibiotic with potent antimicrobial activity against several Gram-positive pathogens

    Directory of Open Access Journals (Sweden)

    Bingyue Xin

    2016-07-01

    Full Text Available Due to the rapidly increasing prevalence of multidrug-resistant bacterial strains, the need for new antimicrobial drugs to treat infections has become urgent. Bacteriocins, which are antimicrobial peptides of bacterial origin, are considered potential alternatives to conventional antibiotics and have attracted widespread attention in recent years. Among these bacteriocins, lantibiotics, especially two-component lantibiotics, exhibit potent antimicrobial activity against some clinically relevant Gram-positive pathogens and have potential applications in the pharmaceutical industry. In this study, we characterized a novel two-component lantibiotic termed thusin that consists of Thsα, Thsβ and Thsβ' (mutation of Thsβ, A14G and that was isolated from a B. thuringiensis strain BGSC 4BT1. Thsα and Thsβ (or Thsβ' exhibit optimal antimicrobial activity at a 1:1 ratio and act sequentially to affect target cells, and they are all highly thermostable (100°C for 30 min and pH tolerant (pH 2.0 to 9.0. Thusin shows remarkable efficacy against all tested Gram-positive bacteria and greater activities than two known lantibiotics thuricin 4A-4 and ticin A4, and one antibiotic vancomycin against various bacterial pathogens (Bacillus cereus, Listeria monocytogenes, Staphylococcus aureus (MRSA, Staphylococcus sciuri, Enterococcus faecalis, and Streptococcus pneumoniae. Moreover, thusin is also able to inhibit the outgrowth of Bacillus cereus spores. The potent antimicrobial activity of thusin against some Gram-positive pathogens indicates that it has potential for the development of new drugs.

  20. Color doppler imaging of subclavian steal phenomenon

    International Nuclear Information System (INIS)

    Cho, Nari Ya; Chung, Tae Sub; Kim, Jai Keun

    1997-01-01

    To evaluate the characteristic color doppler imaging of vertebral artery flow in the subclavian steal phenomenon. The study group consisted of eight patients with reversed vertebral artery flow proved by color Doppler imaging. We classified this flow into two groups:(1) complete reversal;(2) partial reversal, as shown by Doppler velocity waveform. Vertebral angiography was performed in six of eight patients;color Doppler imaging and angiographic findings were compared. On color Doppler imaging, all eight cases with reversed vertebral artery flow showed no signal at the proximal subclavian or brachiocephalic artery. We confirmed shunting of six cases by performing angiography from the contralateral vertebral and basilar artery to the ipsilateral vertebral artery. On the Doppler spectrum, six cases showed complete reversal and two partial reversal. On angiography, one partial reversal case showed complete occlusion of the subclavian artery with abundant collateral circulation of muscular branches of the vertebral artery. On color Doppler imaging, a reversed vertebral artery suggests the subclavian steal phenomenon. In particular, partial reversal waveform may reflect collateral circulation

  1. Patient-exposure data for doppler ultrasound

    International Nuclear Information System (INIS)

    Stewart, H.F.; Silvis, P.X.; Smith, S.W.

    1986-01-01

    In recent years ultrasound imaging and Doppler blood flow measurements have become important tools for use in diagnostic medicine. Commercial pulse-echo imaging equipment was first introduced into commerce in 1963. The first commercial continuous wave Doppler unit was introduced to the marketplace in 1966. As equipment improved and applications developed, the industry experienced rapid growth in the 1970s. One of the more recent growth areas in the application of diagnostic ultrasound has been the use of pulsed Doppler equipment for cardiac applications. Prior to 1976, some continuous wave Doppler ultrasound was used for cardiovascular diagnosis. However, only a single manufacturer marketed a pulsed Doppler clinical instrument for cardiac or peripheral vascular diagnosis. Currently, many continuous wave and pulsed Doppler instruments are commercially available for both peripheral vascular and cardiac diagnosis. This chapter (1) briefly reviews current safety guidelines, regulations, and recommendations for diagnostic ultrasound; (2) discusses the patient-exposure intensities associated with Doppler ultrasound medical equipment and compare these levels of exposure with intensities from other medical ultrasound devices; and (3) considers some of the current information as it relates to the safety of diagnostic ultrasound

  2. Doppler Velocity Signatures of Idealized Elliptical Vortices

    Directory of Open Access Journals (Sweden)

    Wen-Chau Lee

    2006-01-01

    Full Text Available Doppler radar observations have revealed a class of atmospheric vortices (tropical cyclones, tornadoes, dust devils that possess elliptical radar reflectivity signatures. One famous example is Typhoon Herb (1996 that maintained its elliptical reflectivity structure over a 40-hour period. Theoretical work and dual-Doppler analyses of observed tropical cyclones have suggested two physical mechanisms that can explain the formation of two types of elliptical vortices observed in nature, namely, the combination of a circular vortex with either a wavenumber two vortex Rossby wave or a deformation field. The characteristics of these two types of elliptical vortices and their corresponding Doppler velocity signatures have not been previously examined.

  3. Preliminary simulation study of doppler reflectometry

    International Nuclear Information System (INIS)

    Ishii, Yuta; Hojo, Hitoshi; Yoshikawa, Masashi; Ichimura, Makoto; Haraguchi, Yusuke; Imai, Tsuyoshi; Mase, Atsushi

    2010-01-01

    A preliminary simulation study of Doppler reflectometry is performed. The simulations solve Maxwell's equations by a finite difference time domain (FDTD) code method in two dimensions. A moving corrugated metal target is used as a plasma cutoff layer to study the basic features of Doppler reflectometry. We examined the effects of the full width at half maximum (FWHM) of the electromagnetic waves and the corrugation depth of the metal target. Furthermore, the effect of a nonuniform plasma is studied using this FDTD analysis. The Doppler shift and velocity are compared with those obtained from FDTD analysis of a uniform plasma. (author)

  4. Convergence of PASTA kinase and two-component signaling in response to cell wall stress in Enterococcus faecalis.

    Science.gov (United States)

    Kellogg, Stephanie L; Kristich, Christopher J

    2018-04-09

    Two common signal transduction mechanisms used by bacteria to sense and respond to changing environments are two-component systems (TCSs) and eukaryotic-like Ser/Thr kinases and phosphatases (eSTK/Ps). Enterococcus faecalis is a Gram-positive bacterium and serious opportunistic pathogen that relies on both a TCS and an eSTK/P pathway for intrinsic resistance to cell wall-targeting antibiotics. The TCS consists of a histidine kinase (CroS) and response regulator (CroR) that become activated upon exposure of cells to cell wall-targeting antibiotics, leading to modulation of gene expression. The eSTK/P pathway consists of a transmembrane kinase (IreK) and its cognate phosphatase (IreP), which act antagonistically to mediate antibiotic resistance through an unknown mechanism. Because both CroS/R and IreK/P contribute to enterococcal resistance towards cell wall-targeting antibiotics, we hypothesized these signaling systems are intertwined. To test this hypothesis, we analyzed CroR phosphorylation and CroS/R-dependent gene expression to probe the influence of IreK and IreP on CroS/R signaling. In addition, we analyzed the phosphorylation state of CroS which revealed IreK-dependent phosphorylation of a Thr residue important for CroS function. Our results are consistent with a model in which IreK positively influences CroR-dependent gene expression through phosphorylation of CroS to promote antimicrobial resistance in E. faecalis Importance Two-component signaling systems (TCSs) and eukaryotic-like Ser/Thr kinases (eSTKs) are used by bacteria to sense and adapt to changing environments. Understanding how these pathways are regulated to promote bacterial survival is critical for a more complete understanding of bacterial stress responses and physiology. The opportunistic pathogen Enterococcus faecalis relies on both a TCS (CroS/R) and an eSTK (IreK) for intrinsic resistance to cell wall-targeting antibiotics. We probed the relationship between CroS/R and IreK, revealing

  5. Changes in waveform on hepatic venous doppler in patients with chronic hepatic B: Correlation with histologic findings

    International Nuclear Information System (INIS)

    Ko, Joon Seok; Kim, Hak Soo; Chung, Dong Hae

    2001-01-01

    To evaluate changes of the waveform of the hepatic vein on doppler ultrasound (US) in patients with chronic hepatic B and to correlate them with histologic findings. Thirty three patients with chronic hepatic B were prospectively examined with doppler US, and liver biopsy was done at the same time. The right hepatic vein was examined on doppler US, and a liver biopsy was performed in the right lobe of the liver. Doppler waveform was considered abnormal if it showed either reduction in the amplitude of phasic oscillation without the reversed flow phase or the presence of completely flow. Specimens obtained from the biopsy were classified according to the predetermined histologic scoring criteria. It was technically possible to performed Doppler US of the right hepatic vein and liver biopsy simultaneously in all thirty three patients. Waveforms of the right hepatic vein were abnormal in fourteen (42.4%), biphasic in 12 (36.4%) and flat in two (6.0%) patients. Only the steatosis exhibited statistically significant correlation between changes of doppler waveform (p,0.05) of the normal and abnormal groups. Doppler US patterns of the hepatic vein in chronic hepatitis B were different from those of the normal group. The abnormal flow pattern on hepatic venous doppler appeared to be mainly influenced by the intrahepatic fat deposition rather than the degree of fibrosis.

  6. The Next Generation Airborne Polarimetric Doppler Radar

    Science.gov (United States)

    Vivekanandan, J.; Lee, Wen-Chau; Loew, Eric; Salazar, Jorge; Chandrasekar, V.

    2013-04-01

    aircraft in its fleet for airborne atmospheric measurements, including dropsonde, and in situ sampling and remote sensing of clouds, chemistry and aerosols. Therefore, the addition of a precipitation radar to the NSF/NCAR C-130 platform will produce transformational change in its mission. This new design can be cloned for C-130s operated by a number of agencies, including NOAA and the Air Force hurricane reconnaissance fleet. This paper presents a possible configuration of a novel, airborne phased array radar (APAR) to be installed on the NSF/NCAR C-130 aircraft with improved spatial resolution and polarimetric capability to meet or exceed that of ELDORA. The preliminary design, an update of the APAR project, and a future plan will be presented. References: Bell, M. M. , M. T. Montgomery, 2008: Observed Structure, Evolution, and Potential Intensity of Category 5 Hurricane Isabel (2003) from 12 to 14 September. Monthly Weather Review, Vol. 136, Issue 6, pp. 2023-2046. Hildebrand, P. H., W.-C. Lee, C. A. Walther, C. Frush, M. Randall, E. Loew, R. Neitzel, R. Parsons, J. Testud, F. Baudin, and A. LeCornec, 1996: The ELDORA/ASTRAIA airborne Doppler weather radar: High resolution observations from TOGA COARE. Bull. Amer. Metoro. Soc., 77, 213-232 Howard B. Bluestein, Roger M. Wakimoto, 2003: Mobile Radar Observations of Severe Convective Storms re Convective Storms. Meteorological Monographs, Vol. 30, Issue 52, pp. 105-105. Montgomery, M. T., M. M. Bell, S. D. Aberson, M. L. Black, 2006: Hurricane Isabel (2003): New Insights into the Physics of Intense Storms. Part I: Mean Vortex Structure and Maximum Intensity Estimates. Bull. of the American Meteorl. Soc., Vol. 87, Issue 10, pp. 1335-1347.

  7. Preparation and properties of high storage stability polyester polyol dispersion for two-component waterborne polyurethane coating

    Science.gov (United States)

    Hao, H.; Hu, J. Q.; Wang, F.; Tu, W. P.

    2017-01-01

    A new type of polyester polyol dispersion with good storage stability was prepared based on a hydrophilic monomer 5-sodium sulfodimethyl isophthalate (5-SIPM), and frequently-used monomers such as neopentyl glycol (NPG), dimethyl terephthalate (DMT), dimethyl phthalate (DMP) and trimethylolpropane (TMP) by the transpolycondensation and polycondensation method. The polyester polyol dispersion was characterized by FTIR and GPC. The proper content of these monomers were determined by the performance of polyester dispersion: the content of TMP was 15wt%, the content of NPG was 7.5wt% and the hydrophilic monomer 5-SIPM content was 5wt%. Two-component waterborne polyurethane (2K-WPU) coatings were prepared by Bayhydur® XP2487/1 and polyester polyol dispersions, which were stored before and after at 40 ° for 6 weeks, the prepared films have no differences in drying time, adhesion, pencil hardness, gloss and chemical resistance, the result also reveals that the polyester polyol dispersion have excellent storage stability resistance.

  8. Application of two component biodegradable carriers in a particle-fixed biofilm airlift suspension reactor: development and structure of biofilms.

    Science.gov (United States)

    Hille, Andrea; He, Mei; Ochmann, Clemens; Neu, Thomas R; Horn, Harald

    2009-01-01

    Two component biodegradable carriers for biofilm airlift suspension (BAS) reactors were investigated with respect to development of biofilm structure and oxygen transport inside the biofilm. The carriers were composed of PHB (polyhydroxybutyrate), which is easily degradable and PCL (caprolactone), which is less easily degradable by heterotrophic microorganisms. Cryosectioning combined with classical light microscopy and CLSM was used to identify the surface structure of the carrier material over a period of 250 days of biofilm cultivation in an airlift reactor. Pores of 50 to several hundred micrometers depth are formed due to the preferred degradation of PHB. Furthermore, microelectrode studies show the transport mechanism for different types of biofilm structures, which were generated under different substrate conditions. At high loading rates, the growth of a rather loosely structured biofilm with high penetration depths of oxygen was found. Strong changes of substrate concentration during fed-batch mode operation of the reactor enhance the growth of filamentous biofilms on the carriers. Mass transport in the outer regions of such biofilms was mainly driven by advection.

  9. Laplace-transformed atomic orbital-based Møller–Plesset perturbation theory for relativistic two-component Hamiltonians

    Energy Technology Data Exchange (ETDEWEB)

    Helmich-Paris, Benjamin, E-mail: b.helmichparis@vu.nl; Visscher, Lucas, E-mail: l.visscher@vu.nl [Section of Theoretical Chemistry, VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam (Netherlands); Repisky, Michal, E-mail: michal.repisky@uit.no [CTCC, Department of Chemistry, UIT The Arctic University of Norway, N-9037 Tromø (Norway)

    2016-07-07

    We present a formulation of Laplace-transformed atomic orbital-based second-order Møller–Plesset perturbation theory (MP2) energies for two-component Hamiltonians in the Kramers-restricted formalism. This low-order scaling technique can be used to enable correlated relativistic calculations for large molecular systems. We show that the working equations to compute the relativistic MP2 energy differ by merely a change of algebra (quaternion instead of real) from their non-relativistic counterparts. With a proof-of-principle implementation we study the effect of the nuclear charge on the magnitude of half-transformed integrals and show that for light elements spin-free and spin-orbit MP2 energies are almost identical. Furthermore, we investigate the effect of separation of charge distributions on the Coulomb and exchange energy contributions, which show the same long-range decay with the inter-electronic/atomic distance as for non-relativistic MP2. A linearly scaling implementation is possible if the proper distance behavior is introduced to the quaternion Schwarz-type estimates as for non-relativistic MP2.

  10. Calculations of atomic magnetic nuclear shielding constants based on the two-component normalized elimination of the small component method

    Science.gov (United States)

    Yoshizawa, Terutaka; Zou, Wenli; Cremer, Dieter

    2017-04-01

    A new method for calculating nuclear magnetic resonance shielding constants of relativistic atoms based on the two-component (2c), spin-orbit coupling including Dirac-exact NESC (Normalized Elimination of the Small Component) approach is developed where each term of the diamagnetic and paramagnetic contribution to the isotropic shielding constant σi s o is expressed in terms of analytical energy derivatives with regard to the magnetic field B and the nuclear magnetic moment 𝝁 . The picture change caused by renormalization of the wave function is correctly described. 2c-NESC/HF (Hartree-Fock) results for the σiso values of 13 atoms with a closed shell ground state reveal a deviation from 4c-DHF (Dirac-HF) values by 0.01%-0.76%. Since the 2-electron part is effectively calculated using a modified screened nuclear shielding approach, the calculation is efficient and based on a series of matrix manipulations scaling with (2M)3 (M: number of basis functions).

  11. Drift effect and "negative" mass transport in an inhomogeneous medium: limiting case of a two-component lattice gas.

    Science.gov (United States)

    Lukyanets, Sergei P; Kliushnychenko, Oleksandr V

    2010-11-01

    The mass transport in an inhomogeneous medium is modeled as the limiting case of a two-component lattice gas with excluded volume constraint and one of the components fixed. In the long-wavelength approximation, the density relaxation of mobile particles is governed by diffusion and interaction with a medium inhomogeneity represented by the static component distribution. It is shown that the density relaxation can be locally accompanied by density distribution compression, i.e., the local mass transport directed from low-to high-density regions. The origin of such a "negative" mass transport is shown to be associated with the presence of a stationary drift flow defined by the medium inhomogeneity. In the quasi-one-dimensional case, the compression dynamics manifests itself in the hoppinglike motion of packet front position of diffusing substance due to staged passing through inhomogeneity barriers, and it leads to fragmentation of the packet and retardation of its spreading. The root-mean-square displacement reflects only the averaged packet front dynamics and becomes inappropriate as the transport characteristic in this regime. In the stationary case, the mass transport throughout the whole system may be directed from the boundary with lower concentration towards the boundary with higher concentration. Implications of the excluded volume constraint and particle distinguishability for these effects are discussed.

  12. Gene expression of a two-component regulatory system associated with sunscreen biosynthesis in the cyanobacterium Nostoc punctiforme ATCC 29133.

    Science.gov (United States)

    Janssen, Jacob; Soule, Tanya

    2016-01-01

    Long-wavelength ultraviolet radiation (UVA) can damage cells through photooxidative stress, leading to harmful photosensitized proteins and pigments in cyanobacteria. To mitigate damage, some cyanobacteria secrete the UVA-absorbing pigment scytonemin into their extracellular sheath. Comparative genomic analyses suggest that scytonemin biosynthesis is regulated by the two-component regulatory system (TCRS) proteins encoded by Npun_F1277 and Npun_F1278 in the cyanobacterium Nostoc punctiforme ATCC 29133. To understand the dynamics of these genes, their expression was measured following exposure to UVA, UVB, high visible (VIS) irradiance and oxidative stress for 20, 40 and 60 min. Overall, both genes had statistically similar patterns of expression for all four conditions and were generally upregulated, except for those exposed to UVB by 60 min and for the cells under oxidative stress. The greatest UVA response was an upregulation by 20 min, while the response to UVB was the most dramatic and persisted through 40 min. High VIS irradiance resulted in a modest upregulation, while oxidative stress caused a slight downregulation. Both genes were also found to occur on the same transcript. These results demonstrate that these genes are positively responding to several light-associated conditions, which suggests that this TCRS may regulate more than just scytonemin biosynthesis under UVA stress. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  13. Laplace-transformed atomic orbital-based Møller–Plesset perturbation theory for relativistic two-component Hamiltonians

    International Nuclear Information System (INIS)

    Helmich-Paris, Benjamin; Visscher, Lucas; Repisky, Michal

    2016-01-01

    We present a formulation of Laplace-transformed atomic orbital-based second-order Møller–Plesset perturbation theory (MP2) energies for two-component Hamiltonians in the Kramers-restricted formalism. This low-order scaling technique can be used to enable correlated relativistic calculations for large molecular systems. We show that the working equations to compute the relativistic MP2 energy differ by merely a change of algebra (quaternion instead of real) from their non-relativistic counterparts. With a proof-of-principle implementation we study the effect of the nuclear charge on the magnitude of half-transformed integrals and show that for light elements spin-free and spin-orbit MP2 energies are almost identical. Furthermore, we investigate the effect of separation of charge distributions on the Coulomb and exchange energy contributions, which show the same long-range decay with the inter-electronic/atomic distance as for non-relativistic MP2. A linearly scaling implementation is possible if the proper distance behavior is introduced to the quaternion Schwarz-type estimates as for non-relativistic MP2.

  14. Phosphorescence lifetimes of organic light-emitting diodes from two-component time-dependent density functional theory

    Energy Technology Data Exchange (ETDEWEB)

    Kühn, Michael [Institut für Physikalische Chemie, Karlsruher Institut für Technologie, Kaiserstraße 12, 76131 Karlsruhe (Germany); Weigend, Florian, E-mail: florian.weigend@kit.edu [Institut für Physikalische Chemie, Karlsruher Institut für Technologie, Kaiserstraße 12, 76131 Karlsruhe (Germany); Institut für Nanotechnologie, Karlsruher Institut für Technologie, Postfach 3640, 76021 Karlsruhe (Germany)

    2014-12-14

    “Spin-forbidden” transitions are calculated for an eight-membered set of iridium-containing candidate molecules for organic light-emitting diodes (OLEDs) using two-component time-dependent density functional theory. Phosphorescence lifetimes (obtained from averaging over relevant excitations) are compared to experimental data. Assessment of parameters like non-distorted and distorted geometric structures, density functionals, relativistic Hamiltonians, and basis sets was done by a thorough study for Ir(ppy){sub 3} focussing not only on averaged phosphorescence lifetimes, but also on the agreement of the triplet substate structure with experimental data. The most favorable methods were applied to an eight-membered test set of OLED candidate molecules; Boltzmann-averaged phosphorescence lifetimes were investigated concerning the convergence with the number of excited states and the changes when including solvent effects. Finally, a simple model for sorting out molecules with long averaged phosphorescence lifetimes is developed by visual inspection of computationally easily achievable one-component frontier orbitals.

  15. A conserved two-component signal transduction system controls the response to phosphate starvation in Bifidobacterium breve UCC2003.

    Science.gov (United States)

    Alvarez-Martin, Pablo; Fernández, Matilde; O'Connell-Motherway, Mary; O'Connell, Kerry Joan; Sauvageot, Nicolas; Fitzgerald, Gerald F; MacSharry, John; Zomer, Aldert; van Sinderen, Douwe

    2012-08-01

    This work reports on the identification and molecular characterization of the two-component regulatory system (2CRS) PhoRP, which controls the response to inorganic phosphate (P(i)) starvation in Bifidobacterium breve UCC2003. The response regulator PhoP was shown to bind to the promoter region of pstSCAB, specifying a predicted P(i) transporter system, as well as that of phoU, which encodes a putative P(i)-responsive regulatory protein. This interaction is assumed to cause transcriptional modulation under conditions of P(i) limitation. Our data suggest that the phoRP genes are subject to positive autoregulation and, together with pstSCAB and presumably phoU, represent the complete regulon controlled by the phoRP-encoded 2CRS in B. breve UCC2003. Determination of the minimal PhoP binding region combined with bioinformatic analysis revealed the probable recognition sequence of PhoP, designated here as the PHO box, which together with phoRP is conserved among many high-GC-content Gram-positive bacteria. The importance of the phoRP 2CRS in the response of B. breve to P(i) starvation conditions was confirmed by analysis of a B. breve phoP insertion mutant which exhibited decreased growth under phosphate-limiting conditions compared to its parent strain UCC2003.

  16. Functionalization of PDMS modified and plasma activated two-component polyurethane coatings by surface attachment of enzymes

    International Nuclear Information System (INIS)

    Kreider, Alexej; Richter, Katharina; Sell, Stephan; Fenske, Mandus; Tornow, Christian; Stenzel, Volkmar; Grunwald, Ingo

    2013-01-01

    This article describes a new strategy for coupling the enzyme horseradish peroxidase to a two-component polyurethane (2C-PUR) coating. A stable polymer conjugate was achieved by combining the enzyme and the 2C-PUR coating which was modified with poly(dimethylsiloxane) (PDMS), located at the surface. An atmospheric pressure plasma jet system was used to convert alkyl groups from the PDMS into polar silanol functionalities. This conversion was proven by X-ray photoelectron spectroscopy and dynamic contact angle measurements. In addition, the stability of the activated 2C-PUR surface containing silanol groups was determined by measuring the contact angle as a function of time. Compared to the non-modified 2C-PUR systems the one with PDMS displayed a higher stability over a time period over 28 h. In a silanization process the coating was treated with (3-aminopropyl) trimethoxysilane and the enzyme was subsequently immobilized to the coating via the cross linker glutaraldehyde to receive new biomimetic catalytic/enzymatic functions. The chemical immobilization (chemisorption) of the enzyme to the surface showed statistically significant higher biological activity as compared to references samples without using a cross linker (physisorption). The presented technique offers the opportunity to design new and smart multifunctional surface coatings which employ biomimetic capabilities.

  17. A two-component wave equation for particles of spin 1/2 and non-zero rest mass

    International Nuclear Information System (INIS)

    Srivastava, T.

    1981-11-01

    We have discussed here the qualifications of the equation (delta 0 +sigmasup(k)deltasub(k))psi = -kappaTpsi, where deltasub(μ) is identical to delta/deltaxsup(μ), sigmasup(k) are the Pauli spin matrices, T is the linear operator which changes the sign of t, kappa=m 0 c/(h/2π) and psi a function with two components, as a suitable wave equation for a spin 1/2 particle with non-zero rest mass. We have established that both components of all its solutions satisfy the Klein-Gordon equation and that a 1-1 correspondence can be set up between its solutions and the positive energy solutions of the Dirac equation which preserves inner products (suitably defined for our case). We have then gone on to show covariance under transformations of the proper Lorentz group as also under space and time inversions and translations. Eigenfunctions of energy-momentum and spin have been explicitly found and it is shown that causality is preserved and a Green's function exists. A list appears, at the end, of points to be discussed in Part II of this paper, points which, it is hoped, will complete the acceptability of the theory. (author)

  18. The PhoBR two-component system regulates antibiotic biosynthesis in Serratia in response to phosphate

    Science.gov (United States)

    2009-01-01

    Background Secondary metabolism in Serratia sp. ATCC 39006 (Serratia 39006) is controlled via a complex network of regulators, including a LuxIR-type (SmaIR) quorum sensing (QS) system. Here we investigate the molecular mechanism by which phosphate limitation controls biosynthesis of two antibiotic secondary metabolites, prodigiosin and carbapenem, in Serratia 39006. Results We demonstrate that a mutation in the high affinity phosphate transporter pstSCAB-phoU, believed to mimic low phosphate conditions, causes upregulation of secondary metabolism and QS in Serratia 39006, via the PhoBR two-component system. Phosphate limitation also activated secondary metabolism and QS in Serratia 39006. In addition, a pstS mutation resulted in upregulation of rap. Rap, a putative SlyA/MarR-family transcriptional regulator, shares similarity with the global regulator RovA (regulator of virulence) from Yersina spp. and is an activator of secondary metabolism in Serratia 39006. We demonstrate that expression of rap, pigA-O (encoding the prodigiosin biosynthetic operon) and smaI are controlled via PhoBR in Serratia 39006. Conclusion Phosphate limitation regulates secondary metabolism in Serratia 39006 via multiple inter-linked pathways, incorporating transcriptional control mediated by three important global regulators, PhoB, SmaR and Rap. PMID:19476633

  19. The PhoBR two-component system regulates antibiotic biosynthesis in Serratia in response to phosphate

    Directory of Open Access Journals (Sweden)

    Everson Lee

    2009-05-01

    Full Text Available Abstract Background Secondary metabolism in Serratia sp. ATCC 39006 (Serratia 39006 is controlled via a complex network of regulators, including a LuxIR-type (SmaIR quorum sensing (QS system. Here we investigate the molecular mechanism by which phosphate limitation controls biosynthesis of two antibiotic secondary metabolites, prodigiosin and carbapenem, in Serratia 39006. Results We demonstrate that a mutation in the high affinity phosphate transporter pstSCAB-phoU, believed to mimic low phosphate conditions, causes upregulation of secondary metabolism and QS in Serratia 39006, via the PhoBR two-component system. Phosphate limitation also activated secondary metabolism and QS in Serratia 39006. In addition, a pstS mutation resulted in upregulation of rap. Rap, a putative SlyA/MarR-family transcriptional regulator, shares similarity with the global regulator RovA (regulator of virulence from Yersina spp. and is an activator of secondary metabolism in Serratia 39006. We demonstrate that expression of rap, pigA-O (encoding the prodigiosin biosynthetic operon and smaI are controlled via PhoBR in Serratia 39006. Conclusion Phosphate limitation regulates secondary metabolism in Serratia 39006 via multiple inter-linked pathways, incorporating transcriptional control mediated by three important global regulators, PhoB, SmaR and Rap.

  20. Three-body recombination of two-component cold atomic gases into deep dimers in an optical model

    International Nuclear Information System (INIS)

    Mikkelsen, M; Jensen, A S; Fedorov, D V; Zinner, N T

    2015-01-01

    We consider three-body recombination into deep dimers in a mass-imbalanced two-component atomic gas. We use an optical model where a phenomenological imaginary potential is added to the lowest adiabatic hyper-spherical potential. The consequent imaginary part of the energy eigenvalue corresponds to the decay rate or recombination probability of the three-body system. The method is formulated in details and the relevant qualitative features are discussed as functions of scattering lengths and masses. We use zero-range model in analyses of recent recombination data. The dominating scattering length is usually related to the non-equal two-body systems. We account for temperature smearing which tends to wipe out the higher-lying Efimov peaks. The range and the strength of the imaginary potential determine positions and shapes of the Efimov peaks as well as the absolute value of the recombination rate. The Efimov scaling between recombination peaks is calculated and shown to depend on both scattering lengths. Recombination is predicted to be largest for heavy–heavy–light systems. Universal properties of the optical parameters are indicated. We compare to available experiments and find in general very satisfactory agreement. (paper)

  1. Two-Component Structure of the Radio Source 0014+813 from VLBI Observations within the CONT14 Program

    Science.gov (United States)

    Titov, O. A.; Lopez, Yu. R.

    2018-03-01

    We consider a method of reconstructing the structure delay of extended radio sources without constructing their radio images. The residuals derived after the adjustment of geodetic VLBI observations are used for this purpose. We show that the simplest model of a radio source consisting of two point components can be represented by four parameters (the angular separation of the components, the mutual orientation relative to the poleward direction, the flux-density ratio, and the spectral index difference) that are determined for each baseline of a multi-baseline VLBI network. The efficiency of this approach is demonstrated by estimating the coordinates of the radio source 0014+813 observed during the two-week CONT14 program organized by the International VLBI Service (IVS) in May 2014. Large systematic deviations have been detected in the residuals of the observations for the radio source 0014+813. The averaged characteristics of the radio structure of 0014+813 at a frequency of 8.4 GHz can be calculated from these deviations. Our modeling using four parameters has confirmed that the source consists of two components at an angular separation of 0.5 mas in the north-south direction. Using the structure delay when adjusting the CONT14 observations leads to a correction of the average declination estimate for the radio source 0014+813 by 0.070 mas.

  2. A Two-Component Regulatory System Impacts Extracellular Membrane-Derived Vesicle Production in Group A Streptococcus

    Directory of Open Access Journals (Sweden)

    Ulrike Resch

    2016-11-01

    Full Text Available Export of macromolecules via extracellular membrane-derived vesicles (MVs plays an important role in the biology of Gram-negative bacteria. Gram-positive bacteria have also recently been reported to produce MVs; however, the composition and mechanisms governing vesiculogenesis in Gram-positive bacteria remain undefined. Here, we describe MV production in the Gram-positive human pathogen group A streptococcus (GAS, the etiological agent of necrotizing fasciitis and streptococcal toxic shock syndrome. M1 serotype GAS isolates in culture exhibit MV structures both on the cell wall surface and in the near vicinity of bacterial cells. A comprehensive analysis of MV proteins identified both virulence-associated protein substrates of the general secretory pathway in addition to “anchorless surface proteins.” Characteristic differences in the contents, distributions, and fatty acid compositions of specific lipids between MVs and GAS cell membrane were also observed. Furthermore, deep RNA sequencing of vesicular RNAs revealed that GAS MVs contained differentially abundant RNA species relative to bacterial cellular RNA. MV production by GAS strains varied in a manner dependent on an intact two-component system, CovRS, with MV production negatively regulated by the system. Modulation of MV production through CovRS was found to be independent of both GAS cysteine protease SpeB and capsule biosynthesis. Our data provide an explanation for GAS secretion of macromolecules, including RNAs, lipids, and proteins, and illustrate a regulatory mechanism coordinating this secretory response.

  3. X-ray induced specific locus mutations in the ad-3 region of two-component heterokaryons of neurospora crassa

    International Nuclear Information System (INIS)

    Serres, F.J. de; Miller, I.R.

    1988-01-01

    The basis for the reduced growth rates of heterokaryons between strains carrying nonallelic combinations of gene/point mutations and multilocus deletion mutations has been investigated by a simple genetic test. The growth rates of forced 2-component heterokaryons (dikaryons) between multilocus deletion mutations were compared with forced 3-component heterokaryons (trikaryons) containing an ad-3A R ad-3B R double mutant as their third component. Since the third component has no genetic damage at other loci immediately adjacent to the ad-3A or ad-3B locus, the growth rate on minimal medium depends on the functional activity of the unaltered ad-3A and ad-3B loci in the first two components. Tests in the present experiments have shown the ad-3 IR mutations result not only in inactivation of the ad-3 loci by multilocus deletion byt also, in many cases, in partial gene inactivation by an unknown mechanisms at other loci in the immediately adacent regions. The heterozygous effects observed in our present experiments with multilocus deletions in Neurospora can be explained either by a spreading-type position effect of the type found by others in Drosophila, mice, Oenothera and Aspergillus or by undetected genetic damage in the immediately adjacent genetic regions. (author). 18 refs.; 8 figs.; 2 tabs

  4. Functionalization of PDMS modified and plasma activated two-component polyurethane coatings by surface attachment of enzymes

    Energy Technology Data Exchange (ETDEWEB)

    Kreider, Alexej; Richter, Katharina; Sell, Stephan; Fenske, Mandus; Tornow, Christian; Stenzel, Volkmar [Fraunhofer Institute for Manufacturing Technology and Advanced Materials - IFAM, Wiener Strasse 12, 28359 Bremen (Germany); Grunwald, Ingo, E-mail: ingo.grunwald@ifam.fraunhofer.de [Fraunhofer Institute for Manufacturing Technology and Advanced Materials - IFAM, Wiener Strasse 12, 28359 Bremen (Germany)

    2013-05-15

    This article describes a new strategy for coupling the enzyme horseradish peroxidase to a two-component polyurethane (2C-PUR) coating. A stable polymer conjugate was achieved by combining the enzyme and the 2C-PUR coating which was modified with poly(dimethylsiloxane) (PDMS), located at the surface. An atmospheric pressure plasma jet system was used to convert alkyl groups from the PDMS into polar silanol functionalities. This conversion was proven by X-ray photoelectron spectroscopy and dynamic contact angle measurements. In addition, the stability of the activated 2C-PUR surface containing silanol groups was determined by measuring the contact angle as a function of time. Compared to the non-modified 2C-PUR systems the one with PDMS displayed a higher stability over a time period over 28 h. In a silanization process the coating was treated with (3-aminopropyl) trimethoxysilane and the enzyme was subsequently immobilized to the coating via the cross linker glutaraldehyde to receive new biomimetic catalytic/enzymatic functions. The chemical immobilization (chemisorption) of the enzyme to the surface showed statistically significant higher biological activity as compared to references samples without using a cross linker (physisorption). The presented technique offers the opportunity to design new and smart multifunctional surface coatings which employ biomimetic capabilities.

  5. A Unique Fungal Two-Component System Regulates Stress Responses, Drug Sensitivity, Sexual Development, and Virulence of Cryptococcus neoformans

    Science.gov (United States)

    Bahn, Yong-Sun; Kojima, Kaihei; Cox, Gary M.

    2006-01-01

    The stress-activated mitogen-activated protein kinase (MAPK) pathway is widely used by eukaryotic organisms as a central conduit via which cellular responses to the environment effect growth and differentiation. The basidiomycetous human fungal pathogen Cryptococcus neoformans uniquely uses the stress-activated Pbs2-Hog1 MAPK system to govern a plethora of cellular events, including stress responses, drug sensitivity, sexual reproduction, and virulence. Here, we characterized a fungal “two-component” system that controls these fundamental cellular functions via the Pbs2-Hog1 MAPK cascade. A typical response regulator, Ssk1, modulated all Hog1-dependent phenotypes by controlling Hog1 phosphorylation, indicating that Ssk1 is the major upstream signaling component of the Pbs2-Hog1 pathway. A second response regulator, Skn7, governs sensitivity to Na+ ions and the antifungal agent fludioxonil, negatively controls melanin production, and functions independently of Hog1 regulation. To control these response regulators, C. neoformans uses multiple sensor kinases, including two-component–like (Tco) 1 and Tco2. Tco1 and Tco2 play shared and distinct roles in stress responses and drug sensitivity through the Hog1 MAPK system. Furthermore, each sensor kinase mediates unique cellular functions for virulence and morphological differentiation. Our findings highlight unique adaptations of this global two-component MAPK signaling cascade in a ubiquitous human fungal pathogen. PMID:16672377

  6. Noncoherent Doppler tracking: first flight results

    Science.gov (United States)

    DeBoy, Christopher C.; Robert Jensen, J.; Asher, Mark S.

    2005-01-01

    Noncoherent Doppler tracking has been devised as a means to achieve highly accurate, two-way Doppler measurements with a simple, transceiver-based communications system. This technique has been flown as an experiment on the Thermosphere, Ionosphere, Mesosphere, Energetics and Dynamics (TIMED) spacecraft, (launched 7 December 2001), as the operational technique for Doppler tracking on CONTOUR, and is baselined on several future deep space missions at JHU/APL. This paper reports on initial results from a series of successful tests of this technique between the TIMED spacecraft and NASA ground stations in the Deep Space Network. It also examines the advantages that noncoherent Doppler tracking and a transceiver-based system may offer to small satellite systems, including reduced cost, mass, and power.

  7. Doppler coefficient measurements in Zebra Core 5

    International Nuclear Information System (INIS)

    Baker, A.R.; Wheeler, R.C.

    1965-11-01

    Measurements using a central hot loop in Zebra Core 5 are described. Results are given for the Doppler coefficients found in a number of assemblies with PuO 2 and 16% PuO 2 /84% depleted UO 2 pins, loaded with different combinations of steel, sodium or void pins. The mixed oxide results are in general about 20% more negative than was calculated using the FD2 data set, but agreement is good if the plutonium contributions in the calculations are omitted. The small positive Doppler coefficient calculated for Pu239 was not observed, and two measurements indicated instead a small negative effect. The Doppler effect in the mixed oxide systems was found to vary approximately as 1/T. The results from the empty loop and non-fissile assemblies indicate either a small negative Doppler effect in steel or alternatively the presence of an unexplained expansion effect. (author)

  8. Applications of Doppler in the first trimester

    International Nuclear Information System (INIS)

    Taylor, K.J.W.; Ramirez, B.; Grannum, P.

    1986-01-01

    Fifty patients have been studied by duplex Doppler US imaging in the first trimester. In normal gestations, luteal flow, characterized by a low pulsatility index (PI), can be seen in at least one ovary. Failure to detect luteal flow indicates a nonviable pregnancy. Six ectopic pregnancies demonstrated luteal flow and extrauterine heartbeat, detected by Doppler US. High PI values in the uterine artery are seen in the first trimester. Low PI values in the uterine arteries were found in patients with trophoblastic disease

  9. De-Dopplerization of Acoustic Measurements

    Science.gov (United States)

    2017-08-10

    accurate measurement of aircraft location to resample the time signal to account for the compression and expansion of acoustic wavefronts. Correcting...AFRL-RH-WP-TR-2017-0043 DE-DOPPLERIZATION OF ACOUSTIC MEASUREMENTS Frank Mobley, PhD 711 HPW/RHCB Wright-Patterson AFB OH...TITLE AND SUBTITLE DE-DOPPLERIZATION OF ACOUSTIC MEASUREMENTS 5a. CONTRACT NUMBER In-House 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER

  10. Role of the SaeRS two-component regulatory system in Staphylococcus epidermidis autolysis and biofilm formation

    Science.gov (United States)

    2011-01-01

    Background Staphylococcus epidermidis (SE) has emerged as one of the most important causes of nosocomial infections. The SaeRS two-component signal transduction system (TCS) influences virulence and biofilm formation in Staphylococcus aureus. The deletion of saeR in S. epidermidis results in impaired anaerobic growth and decreased nitrate utilization. However, the regulatory function of SaeRS on biofilm formation and autolysis in S. epidermidis remains unclear. Results The saeRS genes of SE1457 were deleted by homologous recombination. The saeRS deletion mutant, SE1457ΔsaeRS, exhibited increased biofilm formation that was disturbed more severely (a 4-fold reduction) by DNase I treatment compared to SE1457 and the complementation strain SE1457saec. Compared to SE1457 and SE1457saec, SE1457ΔsaeRS showed increased Triton X-100-induced autolysis (approximately 3-fold) and decreased cell viability in planktonic/biofilm states; further, SE1457ΔsaeRS also released more extracellular DNA (eDNA) in the biofilms. Correlated with the increased autolysis phenotype, the transcription of autolysis-related genes, such as atlE and aae, was increased in SE1457ΔsaeRS. Whereas the expression of accumulation-associated protein was up-regulated by 1.8-fold in 1457ΔsaeRS, the expression of an N-acetylglucosaminyl transferase enzyme (encoded by icaA) critical for polysaccharide intercellular adhesin (PIA) synthesis was not affected by the deletion of saeRS. Conclusions Deletion of saeRS in S. epidermidis resulted in an increase in biofilm-forming ability, which was associated with increased eDNA release and up-regulated Aap expression. The increased eDNA release from SE1457ΔsaeRS was associated with increased bacterial autolysis and decreased bacterial cell viability in the planktonic/biofilm states. PMID:21702925

  11. Role of the SaeRS two-component regulatory system in Staphylococcus epidermidis autolysis and biofilm formation

    Directory of Open Access Journals (Sweden)

    Francois Patrice

    2011-06-01

    Full Text Available Abstract Background Staphylococcus epidermidis (SE has emerged as one of the most important causes of nosocomial infections. The SaeRS two-component signal transduction system (TCS influences virulence and biofilm formation in Staphylococcus aureus. The deletion of saeR in S. epidermidis results in impaired anaerobic growth and decreased nitrate utilization. However, the regulatory function of SaeRS on biofilm formation and autolysis in S. epidermidis remains unclear. Results The saeRS genes of SE1457 were deleted by homologous recombination. The saeRS deletion mutant, SE1457ΔsaeRS, exhibited increased biofilm formation that was disturbed more severely (a 4-fold reduction by DNase I treatment compared to SE1457 and the complementation strain SE1457saec. Compared to SE1457 and SE1457saec, SE1457ΔsaeRS showed increased Triton X-100-induced autolysis (approximately 3-fold and decreased cell viability in planktonic/biofilm states; further, SE1457ΔsaeRS also released more extracellular DNA (eDNA in the biofilms. Correlated with the increased autolysis phenotype, the transcription of autolysis-related genes, such as atlE and aae, was increased in SE1457ΔsaeRS. Whereas the expression of accumulation-associated protein was up-regulated by 1.8-fold in 1457ΔsaeRS, the expression of an N-acetylglucosaminyl transferase enzyme (encoded by icaA critical for polysaccharide intercellular adhesin (PIA synthesis was not affected by the deletion of saeRS. Conclusions Deletion of saeRS in S. epidermidis resulted in an increase in biofilm-forming ability, which was associated with increased eDNA release and up-regulated Aap expression. The increased eDNA release from SE1457ΔsaeRS was associated with increased bacterial autolysis and decreased bacterial cell viability in the planktonic/biofilm states.

  12. Evolution of multidrug resistance during Staphylococcus aureus infection involves mutation of the essential two component regulator WalKR.

    Directory of Open Access Journals (Sweden)

    Benjamin P Howden

    2011-11-01

    Full Text Available Antimicrobial resistance in Staphylococcus aureus is a major public health threat, compounded by emergence of strains with resistance to vancomycin and daptomycin, both last line antimicrobials. Here we have performed high throughput DNA sequencing and comparative genomics for five clinical pairs of vancomycin-susceptible (VSSA and vancomycin-intermediate ST239 S. aureus (VISA; each pair isolated before and after vancomycin treatment failure. These comparisons revealed a frequent pattern of mutation among the VISA strains within the essential walKR two-component regulatory locus involved in control of cell wall metabolism. We then conducted bi-directional allelic exchange experiments in our clinical VSSA and VISA strains and showed that single nucleotide substitutions within either walK or walR lead to co-resistance to vancomycin and daptomycin, and caused the typical cell wall thickening observed in resistant clinical isolates. Ion Torrent genome sequencing confirmed no additional regulatory mutations had been introduced into either the walR or walK VISA mutants during the allelic exchange process. However, two potential compensatory mutations were detected within putative transport genes for the walK mutant. The minimal genetic changes in either walK or walR also attenuated virulence, reduced biofilm formation, and led to consistent transcriptional changes that suggest an important role for this regulator in control of central metabolism. This study highlights the dramatic impacts of single mutations that arise during persistent S. aureus infections and demonstrates the role played by walKR to increase drug resistance, control metabolism and alter the virulence potential of this pathogen.

  13. Haemophilus parasuis CpxRA two-component system confers bacterial tolerance to environmental stresses and macrolide resistance.

    Science.gov (United States)

    Cao, Qi; Feng, Fenfen; Wang, Huan; Xu, Xiaojuan; Chen, Huanchun; Cai, Xuwang; Wang, Xiangru

    2018-01-01

    Haemophilus parasuis is an opportunistic pathogen localized in the upper respiratory tracts of pigs, its infection begins from bacterial survival under complex conditions, like hyperosmosis, oxidative stress, phagocytosis, and sometimes antibiotics as well. The two-component signal transduction (TCST) system serves as a common stimulus-response mechanism that allows microbes to sense and respond to diverse environmental conditions via a series of phosphorylation reactions. In this study, we investigated the role of TCST system CpxRA in H. parasuis in response to different environmental stimuli by constructing the ΔcpxA and ΔcpxR single deletion mutants as well as the ΔcpxRA double deletion mutant from H. parasuis serotype 4 isolate JS0135. We demonstrated that H. parasuis TCST system CpxRA confers bacterial tolerance to stresses and bactericidal antibiotics. The CpxR was found to play essential roles in mediating oxidative stress, osmotic stresses and alkaline pH stress tolerance, as well as macrolide resistance (i.e. erythromycin), but the CpxA deletion did not decrease bacterial resistance to abovementioned stresses. Moreover, we found via RT-qPCR approach that HAPS_RS00160 and HAPS_RS09425, both encoding multidrug efflux pumps, were significantly decreased in erythromycin challenged ΔcpxR and ΔcpxRA mutants compared with wild-type strain JS0135. These findings characterize the role of the TCST system CpxRA in H. parasuis conferring stress response tolerance and bactericidal resistance, which will deepen our understanding of the pathogenic mechanism in H. parasuis. Copyright © 2017 Elsevier GmbH. All rights reserved.

  14. Evolutionary history of the OmpR/IIIA family of signal transduction two component systems in Lactobacillaceae and Leuconostocaceae

    Directory of Open Access Journals (Sweden)

    González-Candelas Fernando

    2011-02-01

    Full Text Available Abstract Background Two component systems (TCS are signal transduction pathways which typically consist of a sensor histidine kinase (HK and a response regulator (RR. In this study, we have analyzed the evolution of TCS of the OmpR/IIIA family in Lactobacillaceae and Leuconostocaceae, two families belonging to the group of lactic acid bacteria (LAB. LAB colonize nutrient-rich environments such as foodstuffs, plant materials and the gastrointestinal tract of animals thus driving the study of this group of both basic and applied interest. Results The genomes of 19 strains belonging to 16 different species have been analyzed. The number of TCS encoded by the strains considered in this study varied between 4 in Lactobacillus helveticus and 17 in Lactobacillus casei. The OmpR/IIIA family was the most prevalent in Lactobacillaceae accounting for 71% of the TCS present in this group. The phylogenetic analysis shows that no new TCS of this family has recently evolved in these Lactobacillaceae by either lineage-specific gene expansion or domain shuffling. Furthermore, no clear evidence of non-orthologous replacements of either RR or HK partners has been obtained, thus indicating that coevolution of cognate RR and HKs has been prevalent in Lactobacillaceae. Conclusions The results obtained suggest that vertical inheritance of TCS present in the last common ancestor and lineage-specific gene losses appear as the main evolutionary forces involved in their evolution in Lactobacillaceae, although some HGT events cannot be ruled out. This would agree with the genomic analyses of Lactobacillales which show that gene losses have been a major trend in the evolution of this group.

  15. 454 Transcriptome sequencing suggests a role for two-component signalling in cellularization and differentiation of barley endosperm transfer cells.

    Science.gov (United States)

    Thiel, Johannes; Hollmann, Julien; Rutten, Twan; Weber, Hans; Scholz, Uwe; Weschke, Winfriede

    2012-01-01

    Cell specification and differentiation in the endosperm of cereals starts at the maternal-filial boundary and generates the endosperm transfer cells (ETCs). Besides the importance in assimilate transfer, ETCs are proposed to play an essential role in the regulation of endosperm differentiation by affecting development of proximate endosperm tissues. We attempted to identify signalling elements involved in early endosperm differentiation by using a combination of laser-assisted microdissection and 454 transcriptome sequencing. 454 sequencing of the differentiating ETC region from the syncytial state until functionality in transfer processes captured a high proportion of novel transcripts which are not available in existing barley EST databases. Intriguingly, the ETC-transcriptome showed a high abundance of elements of the two-component signalling (TCS) system suggesting an outstanding role in ETC differentiation. All components and subfamilies of the TCS, including distinct kinds of membrane-bound receptors, have been identified to be expressed in ETCs. The TCS system represents an ancient signal transduction system firstly discovered in bacteria and has previously been shown to be co-opted by eukaryotes, like fungi and plants, whereas in animals and humans this signalling route does not exist. Transcript profiling of TCS elements by qRT-PCR suggested pivotal roles for specific phosphorelays activated in a coordinated time flow during ETC cellularization and differentiation. ETC-specificity of transcriptionally activated TCS phosphorelays was assessed for early differentiation and cellularization contrasting to an extension of expression to other grain tissues at the beginning of ETC maturation. Features of candidate genes of distinct phosphorelays and transcriptional activation of genes putatively implicated in hormone signalling pathways hint at a crosstalk of hormonal influences, putatively ABA and ethylene, and TCS signalling. Our findings suggest an integral

  16. MzrA: a novel modulator of the EnvZ/OmpR two-component regulon

    Science.gov (United States)

    Gerken, Henri; Charlson, Emily S; Cicirelli, Elisha M; Kenney, Linda J; Misra, Rajeev

    2009-01-01

    Analysis of suppressors that alleviate the acute envelope stress phenotype of a ΔbamBΔdegP strain of Escherichia coli identified a novel protein MzrA and pleiotropic envZ mutations. Genetic evidence shows that overexpression of MzrA – formerly known as YqjB and EcfM – modulates the activity of EnvZ/OmpR similarly to pleiotropic EnvZ mutants and alter porin expression. However, porin expression in strains devoid of MzrA or overexpressing it is still sensitive to medium osmolarity, pH and procaine, all of which modulate EnvZ/OmpR activities. Thus, MzrA appears to alter the output of the EnvZ/OmpR system but not its ability to receive and respond to various environmental signals. Localization and topology experiments indicate that MzrA is a type II membrane protein, with its N-terminus exposed in the cytoplasm and C-terminus in the periplasm. Bacterial two-hybrid experiments determined that MzrA specifically interacts with EnvZ but not with OmpR or the related membrane sensor kinase, CpxA. This and additional genetic and biochemical evidence suggest that the interaction of MzrA with EnvZ would either enhance EnvZ's kinase activity or reduce its phosphatase activity, thus elevating the steady state levels of OmpR∼P. Furthermore, our data show that MzrA links the two-component envelope stress response regulators, CpxA/CpxR and EnvZ/OmpR. PMID:19432797

  17. a Novel Two-Component Decomposition for Co-Polar Channels of GF-3 Quad-Pol Data

    Science.gov (United States)

    Kwok, E.; Li, C. H.; Zhao, Q. H.; Li, Y.

    2018-04-01

    Polarimetric target decomposition theory is the most dynamic and exploratory research area in the field of PolSAR. But most methods of target decomposition are based on fully polarized data (quad pol) and seldom utilize dual-polar data for target decomposition. Given this, we proposed a novel two-component decomposition method for co-polar channels of GF-3 quad-pol data. This method decomposes the data into two scattering contributions: surface, double bounce in dual co-polar channels. To save this underdetermined problem, a criterion for determining the model is proposed. The criterion can be named as second-order averaged scattering angle, which originates from the H/α decomposition. and we also put forward an alternative parameter of it. To validate the effectiveness of proposed decomposition, Liaodong Bay is selected as research area. The area is located in northeastern China, where it grows various wetland resources and appears sea ice phenomenon in winter. and we use the GF-3 quad-pol data as study data, which which is China's first C-band polarimetric synthetic aperture radar (PolSAR) satellite. The dependencies between the features of proposed algorithm and comparison decompositions (Pauli decomposition, An&Yang decomposition, Yamaguchi S4R decomposition) were investigated in the study. Though several aspects of the experimental discussion, we can draw the conclusion: the proposed algorithm may be suitable for special scenes with low vegetation coverage or low vegetation in the non-growing season; proposed decomposition features only using co-polar data are highly correlated with the corresponding comparison decomposition features under quad-polarization data. Moreover, it would be become input of the subsequent classification or parameter inversion.

  18. Two-component system VicRK regulates functions associated with establishment of Streptococcus sanguinis in biofilms.

    Science.gov (United States)

    Moraes, Julianna J; Stipp, Rafael N; Harth-Chu, Erika N; Camargo, Tarsila M; Höfling, José F; Mattos-Graner, Renata O

    2014-12-01

    Streptococcus sanguinis is a commensal pioneer colonizer of teeth and an opportunistic pathogen of infectious endocarditis. The establishment of S. sanguinis in host sites likely requires dynamic fitting of the cell wall in response to local stimuli. In this study, we investigated the two-component system (TCS) VicRK in S. sanguinis (VicRKSs), which regulates genes of cell wall biogenesis, biofilm formation, and virulence in opportunistic pathogens. A vicK knockout mutant obtained from strain SK36 (SKvic) showed slight reductions in aerobic growth and resistance to oxidative stress but an impaired ability to form biofilms, a phenotype restored in the complemented mutant. The biofilm-defective phenotype was associated with reduced amounts of extracellular DNA during aerobic growth, with reduced production of H2O2, a metabolic product associated with DNA release, and with inhibitory capacity of S. sanguinis competitor species. No changes in autolysis or cell surface hydrophobicity were detected in SKvic. Reverse transcription-quantitative PCR (RT-qPCR), electrophoretic mobility shift assays (EMSA), and promoter sequence analyses revealed that VicR directly regulates genes encoding murein hydrolases (SSA_0094, cwdP, and gbpB) and spxB, which encodes pyruvate oxidase for H2O2 production. Genes previously associated with spxB expression (spxR, ccpA, ackA, and tpK) were not transcriptionally affected in SKvic. RT-qPCR analyses of S. sanguinis biofilm cells further showed upregulation of VicRK targets (spxB, gbpB, and SSA_0094) and other genes for biofilm formation (gtfP and comE) compared to expression in planktonic cells. This study provides evidence that VicRKSs regulates functions crucial for S. sanguinis establishment in biofilms and identifies novel VicRK targets potentially involved in hydrolytic activities of the cell wall required for these functions. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

  19. Remote sensing of particle dynamics: a two-component unmixing model in a western UK shelf sea.

    Science.gov (United States)

    Mitchell, Catherine; Cunningham, Alex

    2014-05-01

    The relationship between the backscattering and absorption coefficients, in particular the backscattering to absorption ratio, is mediated by the type of particles present in the water column. By considering the optical signals to be driven by phytoplankton and suspended minerals, with a relatively constant influence from CDOM, radiative transfer modelling is used to propose a method for retrieving the optical contribution of phytoplankton and suspended minerals to the total absorption coefficient with mean percentage errors of below 5% for both components. These contributions can be converted to constituent concentrations if the appropriate specific inherent optical properties are known or can be determined from the maximum and minimum backscattering to absorption ratios of the data. Remotely sensed absorption and backscattering coefficients from eight years of MODIS data for the Irish Sea reveal maximum backscattering to absorption coefficient ratios over the winter (with an average for the region of 0.27), which then decrease to a minimum over the summer months (with an average of 0.06) before increasing again through to winter, indicating a change in the particles present in the water column. Application of the two-component unmixing model to this data showed seasonal cycles of both phytoplankton and suspended mineral concentrations which vary in both amplitude and periodicity depending on their location. For example, in the Bristol Channel the amplitude of the suspended mineral concentration throughout one cycle is approximately 75% greater than a yearly cycle in the eastern Irish Sea. These seasonal cycles give an insight into the complex dynamics of particles in the water column, indicating the suspension of sediment throughout the winter months and the loss of sediments from the surface layer over the summer during stratification. The relationship between the timing of the phytoplankton spring bloom and changes in the availability of light in the water

  20. Ultrasonography with color Doppler and power Doppler in the diagnosis of periapical lesions

    Science.gov (United States)

    Goel, Sumit; Nagendrareddy, Suma Gundareddy; Raju, Manthena Srinivasa; Krishnojirao, Dayashankara Rao Jingade; Rastogi, Rajul; Mohan, Ravi Prakash Sasankoti; Gupta, Swati

    2011-01-01

    Aim: To evaluate the efficacy of ultrasonography (USG) with color Doppler and power Doppler applications over conventional radiography in the diagnosis of periapical lesions. Materials and Methods: Thirty patients having inflammatory periapical lesions of the maxillary or mandibular anterior teeth and requiring endodontic surgery were selected for inclusion in this study. All patients consented to participate in the study. We used conventional periapical radiographs as well as USG with color Doppler and power Doppler for the diagnosis of these lesions. Their diagnostic performances were compared against histopathologic examination. All data were compared and statistically analyzed. Results: USG examination with color Doppler and power Doppler identified 29 (19 cysts and 10 granulomas) of 30 periapical lesions accurately, with a sensitivity of 100% for cysts and 90.91% for granulomas and a specificity of 90.91% for cysts and 100% for granulomas. In comparison, conventional intraoral radiography identified only 21 lesions (sensitivity of 78.9% for cysts and 45.4% for granulomas and specificity of 45.4% for cysts and 78.9% for granulomas). There was definite correlation between the echotexture of the lesions and the histopathological features except in one case. Conclusions: USG imaging with color Doppler and power Doppler is superior to conventional intraoral radiographic methods for diagnosing the nature of periapical lesions in the anterior jaws. This study reveals the potential of USG examination in the study of other jaw lesions. PMID:22223940

  1. Ultrasonography with color Doppler and power Doppler in the diagnosis of periapical lesions

    International Nuclear Information System (INIS)

    Goel, Sumit; Nagendrareddy, Suma Gundareddy; Raju, Manthena Srinivasa; Krishnojirao, Dayashankara Rao Jingade; Rastogi, Rajul; Mohan, Ravi Prakash Sasankoti; Gupta, Swati

    2011-01-01

    To evaluate the efficacy of ultrasonography (USG) with color Doppler and power Doppler applications over conventional radiography in the diagnosis of periapical lesions. Thirty patients having inflammatory periapical lesions of the maxillary or mandibular anterior teeth and requiring endodontic surgery were selected for inclusion in this study. All patients consented to participate in the study. We used conventional periapical radiographs as well as USG with color Doppler and power Doppler for the diagnosis of these lesions. Their diagnostic performances were compared against histopathologic examination. All data were compared and statistically analyzed. USG examination with color Doppler and power Doppler identified 29 (19 cysts and 10 granulomas) of 30 periapical lesions accurately, with a sensitivity of 100% for cysts and 90.91% for granulomas and a specificity of 90.91% for cysts and 100% for granulomas. In comparison, conventional intraoral radiography identified only 21 lesions (sensitivity of 78.9% for cysts and 45.4% for granulomas and specificity of 45.4% for cysts and 78.9% for granulomas). There was definite correlation between the echotexture of the lesions and the histopathological features except in one case. USG imaging with color Doppler and power Doppler is superior to conventional intraoral radiographic methods for diagnosing the nature of periapical lesions in the anterior jaws. This study reveals the potential of USG examination in the study of other jaw lesions

  2. Ultrasonography with color Doppler and power Doppler in the diagnosis of periapical lesions

    Directory of Open Access Journals (Sweden)

    Sumit Goel

    2011-01-01

    Full Text Available Aim: To evaluate the efficacy of ultrasonography (USG with color Doppler and power Doppler applications over conventional radiography in the diagnosis of periapical lesions. Materials and Methods: Thirty patients having inflammatory periapical lesions of the maxillary or mandibular anterior teeth and requiring endodontic surgery were selected for inclusion in this study. All patients consented to participate in the study. We used conventional periapical radiographs as well as USG with color Doppler and power Doppler for the diagnosis of these lesions. Their diagnostic performances were compared against histopathologic examination. All data were compared and statistically analyzed. Results: USG examination with color Doppler and power Doppler identified 29 (19 cysts and 10 granulomas of 30 periapical lesions accurately, with a sensitivity of 100% for cysts and 90.91% for granulomas and a specificity of 90.91% for cysts and 100% for granulomas. In comparison, conventional intraoral radiography identified only 21 lesions (sensitivity of 78.9% for cysts and 45.4% for granulomas and specificity of 45.4% for cysts and 78.9% for granulomas. There was definite correlation between the echotexture of the lesions and the histopathological features except in one case. Conclusions: USG imaging with color Doppler and power Doppler is superior to conventional intraoral radiographic methods for diagnosing the nature of periapical lesions in the anterior jaws. This study reveals the potential of USG examination in the study of other jaw lesions.

  3. Investigation of the nanoscale two-component ZnS-ZnO heterostructures by means of HR-TEM and X-ray based analysis

    Science.gov (United States)

    Pankin, I. A.; Polozhentsev, O. E.; Soldatov, M. A.; Bugaev, A. L.; Tsaturyan, A.; Lomachenko, K. A.; Guda, A. A.; Budnyk, A. P.; Lamberti, C.; Soldatov, A. V.

    2018-06-01

    This article is devoted to the spectroscopic characterization of ZnS-ZnO nanoscale heterostructures synthesized by the microwave-assisted solvothermal method. The synthesized samples were investigated by means of X-ray powder diffraction (XRPD), high energy resolution fluorescence detected X-ray absorption near-edge-structure (HERFD-XANES) spectroscopy, valence-to-core X-ray emission spectroscopy (VtC-XES) and high resolution transmission electron microscopy (HR-TEM) as well as energy dispersive X-ray spectroscopy (EDX). The average crystallite size estimated by the broadening of XRPD peaks increases from 2.7 nm to 3.7 nm in the temperature range from 100 °C to 150 °C. HR-TEM images show that nanoparticles are arranged in aggregates with the 60-200 nm size. Theoretical estimation shows that the systems synthesized at higher temperatures more prone to the agglomeration. The full profile Reitveld analysis of XRPD data reveals the formation of hexagonal zinc sulfide structure, whereas electron diffraction data reveal also the formation of cubic zinc sulfide and claim the polymorphous character of the system. High energy resolution Zn K-edge XANES data unambiguously demonstrate the presence of a certain amount of the zinc oxide which is likely to have an amorphous structure and could not be detected by XRPD. Qualitative analysis of XANES data allows deriving ZnS/ZnO ratio as a function of synthesis temperature. EDX analysis depicts homogeneous distribution of ZnS and amorphous ZnO phases across the conglomerates. A complementary element-selective valence to core X-ray emission spectroscopy evidences formation of two-component system and confirms estimations of ZnS/ZnO fractions obtained by linear combination fit of XANES data.

  4. Molecular evolution of the two-component system BvgAS involved in virulence regulation in Bordetella.

    Directory of Open Access Journals (Sweden)

    Julien Herrou

    Full Text Available The whooping cough agent Bordetella pertussis is closely related to Bordetella bronchiseptica, which is responsible for chronic respiratory infections in various mammals and is occasionally found in humans, and to Bordetella parapertussis, one lineage of which causes mild whooping cough in humans and the other ovine respiratory infections. All three species produce similar sets of virulence factors that are co-regulated by the two-component system BvgAS. We characterized the molecular diversity of BvgAS in Bordetella by sequencing the two genes from a large number of diverse isolates. The response regulator BvgA is virtually invariant, indicating strong functional constraints. In contrast, the multi-domain sensor kinase BvgS has evolved into two different types. The pertussis type is found in B. pertussis and in a lineage of essentially human-associated B. bronchiseptica, while the bronchiseptica type is associated with the majority of B. bronchiseptica and both ovine and human B. parapertussis. BvgS is monomorphic in B. pertussis, suggesting optimal adaptation or a recent population bottleneck. The degree of diversity of the bronchiseptica type BvgS is markedly different between domains, indicating distinct evolutionary pressures. Thus, absolute conservation of the putative solute-binding cavities of the two periplasmic Venus Fly Trap (VFT domains suggests that common signals are perceived in all three species, while the external surfaces of these domains vary more extensively. Co-evolution of the surfaces of the two VFT domains in each type and domain swapping experiments indicate that signal transduction in the periplasmic region may be type-specific. The two distinct evolutionary solutions for BvgS confirm that B. pertussis has emerged from a specific B. bronchiseptica lineage. The invariant regions of BvgS point to essential parts for its molecular mechanism, while the variable regions may indicate adaptations to different lifestyles. The

  5. Novel Two-Component System of Streptococcus sanguinis Affecting Functions Associated with Viability in Saliva and Biofilm Formation.

    Science.gov (United States)

    Camargo, Tarsila M; Stipp, Rafael N; Alves, Lívia A; Harth-Chu, Erika N; Höfling, José F; Mattos-Graner, Renata O

    2018-04-01

    Streptococcus sanguinis is a pioneer species of teeth and a common opportunistic pathogen of infective endocarditis. In this study, we identified a two-component system, S. sanguinis SptRS (SptRS Ss ), affecting S. sanguinis survival in saliva and biofilm formation. Isogenic mutants of sptR Ss (SKsptR) and sptS Ss (SKsptS) showed reduced cell counts in ex vivo assays of viability in saliva compared to those of parent strain SK36 and complemented mutants. Reduced counts of the mutants in saliva were associated with reduced growth rates in nutrient-poor medium (RPMI) and increased susceptibility to the deposition of C3b and the membrane attach complex (MAC) of the complement system, a defense component of saliva and serum. Conversely, sptR Ss and sptS Ss mutants showed increased biofilm formation associated with higher levels of production of H 2 O 2 and extracellular DNA. Reverse transcription-quantitative PCR (RT-qPCR) comparisons of strains indicated a global role of SptRS Ss in repressing genes for H 2 O 2 production (2.5- to 15-fold upregulation of spxB , spxR , vicR , tpk , and ackA in sptR Ss and sptS Ss mutants), biofilm formation, and/or evasion of host immunity (2.1- to 11.4-fold upregulation of srtA , pcsB , cwdP , iga , and nt5e ). Compatible with the homology of SptR Ss with AraC-type regulators, duplicate to multiple conserved repeats were identified in 1,000-bp regulatory regions of downstream genes, suggesting that SptR Ss regulates transcription by DNA looping. Significant transcriptional changes in the regulatory genes vicR , spxR , comE , comX , and mecA in the sptR Ss and sptS Ss mutants further indicated that SptRS Ss is part of a regulatory network that coordinates cell wall homeostasis, H 2 O 2 production, and competence. This study reveals that SptRS Ss is involved in the regulation of crucial functions for S. sanguinis persistence in the oral cavity. Copyright © 2018 American Society for Microbiology.

  6. Modeling of Doppler frequency shift in multipath radio channels

    Directory of Open Access Journals (Sweden)

    Penzin M.S.

    2016-06-01

    Full Text Available We discuss the modeling of propagation of a quasi-monochromatic radio signal, represented by a coherent pulse sequence, in a non-stationary multipath radio channel. In such a channel, signal propagation results in the observed frequency shift for each ray (Doppler effect. The modeling is based on the assumption that during propagation of a single pulse a channel can be considered stationary. A phase variation in the channel transfer function is shown to cause the observed frequency shift in the received signal. Thus, instead of measuring the Doppler frequency shift, we can measure the rate of variation in the mean phase of one pulse relative to another. The modeling is carried out within the framework of the method of normal waves. The method enables us to model the dynamics of the electromagnetic field at a given point with the required accuracy. The modeling reveals that a local change in ionospheric conditions more severely affects the rays whose reflection region is in the area where the changes occur.

  7. Doppler-guided retrograde catheterization system

    Science.gov (United States)

    Frazin, Leon J.; Vonesh, Michael J.; Chandran, Krishnan B.; Khasho, Fouad; Lanza, George M.; Talano, James V.; McPherson, David D.

    1991-05-01

    The purpose of this study was to investigate a Doppler guided catheterization system as an adjunctive or alternative methodology to overcome the disadvantages of left heart catheterization and angiography. These disadvantages include the biological effects of radiation and the toxic and volume effects of iodine contrast. Doppler retrograde guidance uses a 20 MHz circular pulsed Doppler crystal incorporated into the tip of a triple lumen multipurpose catheter and is advanced retrogradely using the directional flow information provided by the Doppler waveform. The velocity detection limits are either 1 m/second or 4 m/second depending upon the instrumentation. In a physiologic flow model of the human aortic arch, multiple data points revealed a positive wave form when flow was traveling toward the catheter tip indicating proper alignment for retrograde advancement. There was a negative wave form when flow was traveling away from the catheter tip if the catheter was in a branch or bent upon itself indicating improper catheter tip position for retrograde advancement. In a series of six dogs, the catheter was able to be accurately advanced from the femoral artery to the left ventricular chamber under Doppler signal guidance without the use of x-ray. The potential applications of a Doppler guided retrograde catheterization system include decreasing time requirements and allowing safer catheter guidance in patients with atherosclerotic vascular disease and suspected aortic dissection. The Doppler system may allow left ventricular pressure monitoring in the intensive care unit without the need for x-ray and it may allow left sided contrast echocardiography. With pulse velocity detection limits of 4 m/second, this system may allow catheter direction and passage into the aortic root and left ventricle in patients with aortic stenosis. A modification of the Doppler catheter may include transponder technology which would allow precise catheter tip localization once the

  8. Editorial special issue on "Laser Doppler vibrometry"

    Science.gov (United States)

    Vanlanduit, Steve; Dirckx, Joris

    2017-12-01

    The invention of the laser in 1960 has opened up many opportunities in the field of measurement science and technology. Just a few years after the invention of the laser, a novel fluid flow measurement technique based on the Doppler effect was introduced: at that moment the laser Doppler anemometer or shortly LDA [1] was born. The technique enabled fluid velocity measurement by using the light of a He-Ne beam which was scattered by very small polystyrene spheres entrained in the fluid. Later on, in the late nineteen seventees it was recognized that the detection of the Doppler frequency shift that occurs when light is scattered by a moving surface can also be used to measure the vibration velocity of an object. The instrument to perform these vibration measurements was called the laser Doppler vibrometer or LDV [2]. In the last decades several technological advances were made in the field of laser Doppler vibrometry. The result is that nowadays, velocity measurements of fluids (using LDA) and vibrating objects (using LDV) are performed in many challenging applications in different fields (microelectronics, civil structures, biomedical engineering, material science, etc.).

  9. Development of the doppler electron velocimeter: theory.

    Energy Technology Data Exchange (ETDEWEB)

    Reu, Phillip L.

    2007-03-01

    Measurement of dynamic events at the nano-scale is currently impossible. This paper presents the theoretical underpinnings of a method for making these measurements using electron microscopes. Building on the work of Moellenstedt and Lichte who demonstrated Doppler shifting of an electron beam with a moving electron mirror, further work is proposed to perfect and utilize this concept in dynamic measurements. Specifically, using the concept of ''fringe-counting'' with the current principles of transmission electron holography, an extension of these methods to dynamic measurements is proposed. A presentation of the theory of Doppler electron wave shifting is given, starting from the development of the de Broglie wave, up through the equations describing interference effects and Doppler shifting in electron waves. A mathematical demonstration that Doppler shifting is identical to the conceptually easier to understand idea of counting moving fringes is given by analogy to optical interferometry. Finally, potential developmental experiments and uses of a Doppler electron microscope are discussed.

  10. The relationship between VHF radar auroral backscatter amplitude and Doppler velocity: a statistical study

    Directory of Open Access Journals (Sweden)

    B. A. Shand

    Full Text Available A statistical investigation of the relationship between VHF radar auroral backscatter intensity and Doppler velocity has been undertaken with data collected from 8 years operation of the Wick site of the Sweden And Britain Radar-auroral Experiment (SABRE. The results indicate three different regimes within the statistical data set; firstly, for Doppler velocities <200 m s–1, the backscatter intensity (measured in decibels remains relatively constant. Secondly, a linear relationship is observed between the backscatter intensity (in decibels and Doppler velocity for velocities between 200 m s–1 and 700 m s–1. At velocities greater than 700 m s–1 the backscatter intensity saturates at a maximum value as the Doppler velocity increases. There are three possible geophysical mechanisms for the saturation in the backscatter intensity at high phase speeds: a saturation in the irregularity turbulence level, a maximisation of the scattering volume, and a modification of the local ambient electron density. There is also a difference in the dependence of the backscatter intensity on Doppler velocity for the flow towards and away from the radar. The results for flow towards the radar exhibit a consistent relationship between backscatter intensity and measured velocities throughout the solar cycle. For flow away from the radar, however, the relationship between backscatter intensity and Doppler velocity varies during the solar cycle. The geometry of the SABRE system ensures that flow towards the radar is predominantly associated with the eastward electrojet, and flow away is associated with the westward electrojet. The difference in the backscatter intensity variation as a function of Doppler velocity is attributed to asymmetries between the eastward and westward electrojets and the geophysical parameters controlling the backscatter amplitude.

  11. The relationship between VHF radar auroral backscatter amplitude and Doppler velocity: a statistical study

    Directory of Open Access Journals (Sweden)

    B. A. Shand

    1996-08-01

    Full Text Available A statistical investigation of the relationship between VHF radar auroral backscatter intensity and Doppler velocity has been undertaken with data collected from 8 years operation of the Wick site of the Sweden And Britain Radar-auroral Experiment (SABRE. The results indicate three different regimes within the statistical data set; firstly, for Doppler velocities <200 m s–1, the backscatter intensity (measured in decibels remains relatively constant. Secondly, a linear relationship is observed between the backscatter intensity (in decibels and Doppler velocity for velocities between 200 m s–1 and 700 m s–1. At velocities greater than 700 m s–1 the backscatter intensity saturates at a maximum value as the Doppler velocity increases. There are three possible geophysical mechanisms for the saturation in the backscatter intensity at high phase speeds: a saturation in the irregularity turbulence level, a maximisation of the scattering volume, and a modification of the local ambient electron density. There is also a difference in the dependence of the backscatter intensity on Doppler velocity for the flow towards and away from the radar. The results for flow towards the radar exhibit a consistent relationship between backscatter intensity and measured velocities throughout the solar cycle. For flow away from the radar, however, the relationship between backscatter intensity and Doppler velocity varies during the solar cycle. The geometry of the SABRE system ensures that flow towards the radar is predominantly associated with the eastward electrojet, and flow away is associated with the westward electrojet. The difference in the backscatter intensity variation as a function of Doppler velocity is attributed to asymmetries between the eastward and westward electrojets and the geophysical parameters controlling the backscatter amplitude.

  12. Two-dimensional intraventricular flow mapping by digital processing conventional color-Doppler echocardiography images.

    Science.gov (United States)

    Garcia, Damien; Del Alamo, Juan C; Tanne, David; Yotti, Raquel; Cortina, Cristina; Bertrand, Eric; Antoranz, José Carlos; Perez-David, Esther; Rieu, Régis; Fernandez-Aviles, Francisco; Bermejo, Javier

    2010-10-01

    Doppler echocardiography remains the most extended clinical modality for the evaluation of left ventricular (LV) function. Current Doppler ultrasound methods, however, are limited to the representation of a single flow velocity component. We thus developed a novel technique to construct 2D time-resolved (2D+t) LV velocity fields from conventional transthoracic clinical acquisitions. Combining color-Doppler velocities with LV wall positions, the cross-beam blood velocities were calculated using the continuity equation under a planar flow assumption. To validate the algorithm, 2D Doppler flow mapping and laser particle image velocimetry (PIV) measurements were carried out in an atrio-ventricular duplicator. Phase-contrast magnetic resonance (MR) acquisitions were used to measure in vivo the error due to the 2D flow assumption and to potential scan-plane misalignment. Finally, the applicability of the Doppler technique was tested in the clinical setting. In vitro experiments demonstrated that the new method yields an accurate quantitative description of the main vortex that forms during the cardiac cycle (mean error for vortex radius, position and circulation). MR image analysis evidenced that the error due to the planar flow assumption is close to 15% and does not preclude the characterization of major vortex properties neither in the normal nor in the dilated LV. These results are yet to be confirmed by a head-to-head clinical validation study. Clinical Doppler studies showed that the method is readily applicable and that a single large anterograde vortex develops in the healthy ventricle while supplementary retrograde swirling structures may appear in the diseased heart. The proposed echocardiographic method based on the continuity equation is fast, clinically-compliant and does not require complex training. This technique will potentially enable investigators to study of additional quantitative aspects of intraventricular flow dynamics in the clinical setting by

  13. Doppler shift simulation of scattered HF signals during the Tromsø HF pumping experiment on 16 February 1996

    Directory of Open Access Journals (Sweden)

    T. D. Borisova

    2002-09-01

    Full Text Available Comparisons between bistatic scatter measurements and simulation results during the Tromsø HF pumping experiment on 16 February 1996 are made. Doppler measurements of an HF diagnostic signal scattered from the field-aligned irregularities (FAIs in the auroral E-region were carried out on the London – Tromsø – St. Petersburg path at 9410 kHz from 21:00 to 22:00 UT. The scattered signals were observed both from natural and artificial ionospheric irregularities located in the vicinity of Tromsø. To simulate the Doppler frequency shifts, fd , of scattered signals, a radio channel model, named CONE, was developed. The model allows for ray tracing, group and phase paths, and Doppler frequency shift calculations. The calculated Doppler shifts were analyzed for dependence on the magnitude and direction of plasma velocities in the scattering volume. It was found that the velocity components in the north-south direction are crucial for explaining the Doppler frequency shifts of the scattered diagnostic signals. To simulate fd , real velocities obtained from the EISCAT UHF radar at an altitude of 278 km and from the digital all-sky imager during the experiment were employed. The simulation results of Doppler frequency shift variations with time are in reasonable agreement with the experimental Doppler shifts of scattered signals on the London – Tromsø – St. Petersburg path.Key words. Ionosphere (active experiments; ionospheric irregularities Radio science (ionospheric propagation

  14. Arm locking with Doppler estimation errors

    Energy Technology Data Exchange (ETDEWEB)

    Yu Yinan; Wand, Vinzenz; Mitryk, Shawn; Mueller, Guido, E-mail: yinan@phys.ufl.ed [Department of Physics, University of Florida, Gainesville, FL 32611 (United States)

    2010-05-01

    At the University of Florida we developed the University of Florida LISA Interferometer Simulator (UFLIS) in order to study LISA interferometry with hardware in the loop at a system level. One of the proposed laser frequency stabilization techniques in LISA is arm locking. Arm locking uses an adequately filtered linear combination of the LISA arm signals as a frequency reference. We will report about experiments in which we demonstrated arm locking using UFLIS. During these experiments we also discovered a problem associated with the Doppler shift of the return beam. The initial arm locking publications assumed that this Doppler shift can perfectly be subtracted inside the phasemeter or adds an insignificant offset to the sensor signal. However, the remaining Doppler knowledge error will cause a constant change in the laser frequency if unaccounted for. Several ways to circumvent this problem have been identified. We performed detailed simulations and started preliminary experiments to verify the performance of the proposed new controller designs.

  15. Inline Ultrasonic Rheometry by Pulsed Doppler

    Energy Technology Data Exchange (ETDEWEB)

    Pfund, David M.; Greenwood, Margaret S.; Bamberger, Judith A.; Pappas, Richard A.

    2006-12-22

    This will be a discussion of the non-invasive determination of the viscosity of a non-Newtonian fluid in laminar pipe flow over the range of shear rates present in the pipe. The procedure used requires knowledge of the flow profile in and the pressure drop along a long straight run of pipe. The profile is determined by using a pulsed ultrasonic Doppler velocimeter. This approach is ideal for making non-invasive, real-time measurements for monitoring and control. Rheograms of a shear thinning, thixotropic gel will be presented. The operating parameters and limitations of the Doppler-based instrument will be discussed. The most significant limitation is velocity gradient broadening of the Doppler spectra near the walls of the pipe. This limitation can be significant for strongly shear thinning fluids (depending also on the ratio of beam to pipe diameter and the transducer's insertion angle).

  16. Molecules cooled below the Doppler limit

    Science.gov (United States)

    Truppe, S.; Williams, H. J.; Hambach, M.; Caldwell, L.; Fitch, N. J.; Hinds, E. A.; Sauer, B. E.; Tarbutt, M. R.

    2017-12-01

    Magneto-optical trapping and sub-Doppler cooling have been essential to most experiments with quantum degenerate gases, optical lattices, atomic fountains and many other applications. A broad set of new applications await ultracold molecules, and the extension of laser cooling to molecules has begun. A magneto-optical trap (MOT) has been demonstrated for a single molecular species, SrF, but the sub-Doppler temperatures required for many applications have not yet been reached. Here we demonstrate a MOT of a second species, CaF, and we show how to cool these molecules to 50 μK, well below the Doppler limit, using a three-dimensional optical molasses. These ultracold molecules could be loaded into optical tweezers to trap arbitrary arrays for quantum simulation, launched into a molecular fountain for testing fundamental physics, and used to study collisions and chemistry between atoms and molecules at ultracold temperatures.

  17. Wide Angle Michelson Doppler Imaging Interferometer (WAMDII)

    Science.gov (United States)

    Roberts, B.

    1986-01-01

    The wide angle Michelson Doppler imaging interferometer (WAMDII) is a specialized type of optical Michelson interferometer working at sufficiently long path difference to measure Doppler shifts and to infer Doppler line widths of naturally occurring upper atmospheric Gaussian line emissions. The instrument is intended to measure vertical profiles of atmospheric winds and temperatures within the altitude range of 85 km to 300 km. The WAMDII consists of a Michelson interferometer followed by a camera lens and an 85 x 106 charge coupled device photodiode array. Narrow band filters in a filter wheel are used to isolate individual line emissions and the lens forms an image of the emitting region on the charge coupled device array.

  18. Diabetic Nephropathy : Evaluation with Doppler Ultrasonography

    International Nuclear Information System (INIS)

    Sim, Jung Suk; Kim, Seung Hyup; Kang, Heung Sik; Park, Jae Hyung; Han, Man Chung

    1996-01-01

    To compare Doppler ultrasonography with laboratory tests in evaluation of diabetic nephropathy. Fifty-five patients (mean age = 60, M : F = 26 : 29) with diabetes mellitus underwent renal Doppler ultrasonography. Resistive indices were compared with degree of proteinuria, serum creatinine level, and creatinine clearance rate. Eighteen patients who showed no proteinuria or microscopic proteinuria had a mean resistive index (RI) of 0.72 (SD, 0.05), 16 patients with macroscopic proteinuria without nephrotic syndrome had a mean RI of 0.82 (SD, 0.13), and 21 patients with nephrotic syndrome had a mean RI of 0.90 (SD, 0.12). Renal RI correlated highly with serum creatinine level (r = 0.62) and creatinine clearance rate (r = -0.43). Renal Doppler ultrasonography provides a useful indication of renal function in diabetic nephropathy but cannot offer an advantage over conventional laboratory test

  19. Gallblader varices in children with portal cavernoma: duplex-Doppler and color Doppler ultrasound studies

    International Nuclear Information System (INIS)

    Muro, D.; Sanguesa, C.; Lopez, A.

    1998-01-01

    To determine the prevalence of varices in the gallbladder wall, observed by duplex-Doppler and color Doppler ultrasound, in children with cavernoma of the portal vein. Nineteen patients with portal hypertension were studied prospectively by duplex-Doppler and color Doppler ultrasound: 12 of the patients had developed a cavernoma of the portal vein. The presence of peri vesicular varices was assessed in the group of patients with portal cavernoma. Duplex-Doppler and color Doppler ultrasound disclosed the presence of varices in gallbladder wall in nine of the 12 patients (75%). The varices appeared as anechoic and serpiginous areas, and Doppler ultrasound revealed slowed venous flow. However, the three patients in whom gallbldder varices were not detected presented collateral gastric ciculation and spontaneous splenorenal shunt. Gallbladder varices are common in children with portal vein cavernoma; they present hepatopetal flow. Their developments is not related to the size of the portal cavernoma, the presence of spontaneous portosystemic shunts, or endoscopic obliteration of gastric and esophageal varices. The detection of gallbladder varices in patients with portal hypertension who are to undergo biliary surgery is highly important for the surgeon, helping to avoid perioperative complications. (Author) 15 refs

  20. Proposed protocols for peripheral and renal Doppler

    International Nuclear Information System (INIS)

    Fonseca Portuguez, Adriana

    2009-01-01

    A literature review was performed in order to prepare a summary of the important concepts of Doppler and applications in peripheral vascular evaluation and renal. The normal characteristics are summarized and explained in each vascular system and diagnostic criteria of the disorders frequently encountered in practice. Requested more studies have been identified and proposed protocols and report sheets have been developed to standardize the methodology of realization of several Doppler studies. The variability between operators has been treated to reduce as much as possible and follow-up studies have provided in patients who need. (author) [es

  1. A demonstrator for an incoherent Doppler wind lidar receiver

    Science.gov (United States)

    Fabre, F.; Marini, A.; Sidler, Thomas C.; Morancais, Didier; Fongy, G.; Vidal, Ph.

    2018-04-01

    The knowledge of wind fields for a global terrestrial coverage and accurate altitude sampling is one of the main keys for improvement of meteorological predictions and general understanding of atmosphere behaviour. The best way to recover this information is remote sensing from space using low Earth orbit satellites. The measurement principle is to analyse the Doppler shift of the flux emitted by the space instrument and backscattered by the atmosphere. One of the most promising principle for Doppler shift measurement is the direct detection which does not need local oscillators. what significantly simplifies the design of such a space-borne receiver. ESA-ESTEC initiated at early 95' a programme called "lncoherent Doppler Wind Lidar (IDWL) technologies" for the study and bread-boarding phase. MMS won this contract proposing an original concept based on the use of a Fizeau high resolution interferometer working in the UV band. coupled with an intensified CCD. This concept is patented by MMS, as well as the special CCD timing sequence that will be depicted below. The programme begun by a study of the space-borne instrument in order to identify main constraints and define the receiver as could be for a flight model. A detailed performance model was established and parametric analysis allowed to optimise the concept in order to reach required performances. This study phase finally provided the definition of a bread-board for expected performances demonstration. Moreover, the Laser Signal Simulator (LSS) which is used to simulate the Lidar echo in term of amplitude as well as frequency modulation was defined at this step. The performances of this test support equipment are of main importance for the validation of the demonstrator design and performances. The second part of the study aimed at defining the derailed design of the demonstrator and associated test support equipment as well as initiating preliminary validation experiments on most critical technologies, like

  2. Toward Exploring the Synergy Between Cloud Radar Polarimetry and Doppler Spectral Analysis in Deep Cold Precipitating Systems in the Arctic

    Science.gov (United States)

    Oue, Mariko; Kollias, Pavlos; Ryzhkov, Alexander; Luke, Edward P.

    2018-03-01

    The study of Arctic ice and mixed-phase clouds, which are characterized by a variety of ice particle types in the same cloudy volume, is challenging research. This study illustrates a new approach to qualitative and quantitative analysis of the complexity of ice and mixed-phase microphysical processes in Arctic deep precipitating systems using the combination of Ka-band zenith-pointing radar Doppler spectra and quasi-vertical profiles of polarimetric radar variables measured by a Ka/W-band scanning radar. The results illustrate the frequent occurrence of multimodal Doppler spectra in the dendritic/planar growth layer, where locally generated, slower-falling particle populations are well separated from faster-falling populations in terms of Doppler velocity. The slower-falling particle populations contribute to an increase of differential reflectivity (ZDR), while an enhanced specific differential phase (KDP) in this dendritic growth temperature range is caused by both the slower and faster-falling particle populations. Another area with frequent occurrence of multimodal Doppler spectra is in mixed-phase layers, where both populations produce ZDR and KDP values close to 0, suggesting the occurrence of a riming process. Joint analysis of the Doppler spectra and the polarimetric radar variables provides important insight into the microphysics of snow formation and allows the separation of the contributions of ice of different habits to the values of reflectivity and ZDR.

  3. Distribution of Doppler Redshifts of Associated Absorbers of SDSS ...

    Indian Academy of Sciences (India)

    The authors searched all ... quasar, where the contribution of the Doppler motion is relatively small. ..... might contribute to the Doppler redshift distribution. 5. ... out accounting for the contamination of intervening absorption systems, which can.

  4. GRIP DOPPLER AEROSOL WIND LIDAR (DAWN) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The GRIP Doppler Aerosol WiNd Lidar (DAWN) Dataset was collected by the Doppler Aerosol WiNd (DAWN), a pulsed lidar, which operated aboard a NASA DC-8 aircraft...

  5. Operational Bright-Band Snow Level Detection Using Doppler Radar

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A method to detect the bright-band snow level from radar reflectivity and Doppler vertical velocity data collection with an atmospheric profiling Doppler radar. The...

  6. TCSP ER-2 DOPPLER RADAR (EDOP) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The EDOP provides vertically profiled reflectivity and Doppler velocity at aircraft nadir along the flight track. The ER-2 Doppler radar (EDOP) is an X-band (9.6...

  7. ISAR imaging using the instantaneous range instantaneous Doppler method

    CSIR Research Space (South Africa)

    Wazna, TM

    2015-10-01

    Full Text Available In Inverse Synthetic Aperture Radar (ISAR) imaging, the Range Instantaneous Doppler (RID) method is used to compensate for the nonuniform rotational motion of the target that degrades the Doppler resolution of the ISAR image. The Instantaneous Range...

  8. Comparison of power Doppler and color Doppler ultrasonography in the detection of intrasticular blood flow of normal infants

    International Nuclear Information System (INIS)

    Shin, Sung Ran; Lee, Ho Kyoung; Lee, Won Gyun; Youk, Dong Joon; Rho, Taek Soo; Lee, Min Jin; Lee, Sang Chun

    1999-01-01

    To compare color Doppler ultrasonography (US) and power Doppler US in the detection of intratesticular blood flow in normal infants and to asses the symmetry of blood flow. Testicular blood flow was assessed prospectively in 100 testes of 50 infants with both power and color Doppler US. We compared the power Doppler with color Doppler to detect intratesticular blood. When the flow was detected, intratesticular blood flow was graded as follows: grade 1: single intratesticular Doppler signal ; grade 2: multiple intratesticular Doppler signals. The symmetry of intratesticular flow was assessed by using the same method. Intratesticular flow was detected in 72 (72%) and 68 (68%) testes on power and color Doppler US, respectively. In 76 testes (76%), intratesticular flow was detected in either one or both techniques. On power Doppler US, grade 1 was seen in 40 tests and grade 2 in 32 testes. On color Doppler US, grade 1 was noted in 52 testes and grade 2 in 16 testes. Testicular blood flow was symmetric on both power and color Doppler US in each patient. There was no difference between power Doppler and color Doppler ultrasonography in detecting intratesticular blood flow in normal infants.

  9. Magnetization damping in two-component metal oxide micropowder and nanopowder compacts by broadband ferromagnetic resonance measurements

    Science.gov (United States)

    Youssef, Jamal Ben; Brosseau, Christian

    2006-12-01

    The microwave damping mechanisms in magnetic inhomogeneous systems have displayed a richness of phenomenology that has attracted widespread interest over the years. Motivated by recent experiments, we report an extensive experimental study of the Gilbert damping parameter of multicomponent metal oxides micro- and nanophases. We label the former by M samples, and the latter by N samples. The main thrust of this examination is the magnetization dynamics in systems composed of mixtures of magnetic (γ-Fe2O3) and nonmagnetic (ZnO and epoxy resin) materials fabricated via powder processing. Detailed ferromagnetic resonance (FMR) measurements on N and M samples are described so to determine changes in the microwave absorption over the 6-18GHz frequency range as a function of composition and static magnetic field. The FMR linewidth and the field dependent resonance were measured for the M and N samples, at a given volume fraction of the magnetic phase. The asymmetry in the form and change in the linewidth for the M samples are caused by the orientation distribution of the local anisotropy fields, whereas the results for the N samples suggest that the linewidth is very sensitive to details of the spatial magnetic inhomogeneities. For N samples, the peak-to-peak linewidth increases continuously with the volume content of magnetic material. The influence of the volume fraction of the magnetic phase on the static internal field was also investigated. Furthermore, important insights are gleaned through analysis of the interrelationship between effective permeability and Gilbert damping constant. Different mechanisms have been considered to explain the FMR linewidth: the intrinsic Gilbert damping, the broadening induced by the magnetic inhomogeneities, and the extrinsic magnetic relaxation. We observed that the effective Gilbert damping constant of the series of N samples are found to be substantially smaller in comparison to M samples. This effect is attributed to the surface

  10. Transcranial Doppler velocimetry in aneurysmal subarachnoid haemorrhage

    DEFF Research Database (Denmark)

    Staalsø, J M; Edsen, T; Romner, B

    2013-01-01

    -coded transcranial Doppler (TCCD), with the secondary aim of describing prediction of angiographic vasospasm and mortality. METHODS: /st>Sixty patients and 70 healthy controls were each examined in duplicate by alternating operators. A total of 939 measurements divided on 201 examination sets were conducted by four...

  11. Doppler Sonographic Evaluation of Venogenic Extremity Swellings ...

    African Journals Online (AJOL)

    2017-09-14

    Sep 14, 2017 ... potentially lead to many complications including life-threatening pulmonary arterial thrombosis. Screening and confirmation ... and exclusion of acute lower extremity DVT. Duplex ultrasound is considered as the ... this study evaluates the role of Doppler sonography in the clinical management of suspected.

  12. Doppler Shift Compensation Schemes in VANETs

    Directory of Open Access Journals (Sweden)

    F. Nyongesa

    2015-01-01

    Full Text Available Over the last decade vehicle-to-vehicle (V2V communication has received a lot of attention as it is a crucial issue in intravehicle communication as well as in Intelligent Transportation System (ITS. In ITS the focus is placed on integration of communication between mobile and fixed infrastructure to execute road safety as well as nonsafety information dissemination. The safety application such as emergence alerts lays emphasis on low-latency packet delivery rate (PDR, whereas multimedia and infotainment call for high data rates at low bit error rate (BER. The nonsafety information includes multimedia streaming for traffic information and infotainment applications such as playing audio content, utilizing navigation for driving, and accessing Internet. A lot of vehicular ad hoc network (VANET research has focused on specific areas including channel multiplexing, antenna diversity, and Doppler shift compensation schemes in an attempt to optimize BER performance. Despite this effort few surveys have been conducted to highlight the state-of-the-art collection on Doppler shift compensation schemes. Driven by this cause we survey some of the recent research activities in Doppler shift compensation schemes and highlight challenges and solutions as a stock-taking exercise. Moreover, we present open issues to be further investigated in order to address the challenges of Doppler shift in VANETs.

  13. Fifty Years of HF Doppler Observations

    Directory of Open Access Journals (Sweden)

    T Ogawa

    2009-04-01

    Full Text Available High frequency Doppler observations of the ionosphere began in August of 1957 in Kyoto. The number of the observation points worldwide were about 40 in 1980 and are about 20 at present. By this method the movement of the ionosphere reflection height and electron density below the height can be observed. Such variations are occurred by a wide variety of sources.

  14. Ultrasonic Doppler color in glaucoma: Concordance study

    International Nuclear Information System (INIS)

    Uriza, Felipe; Useche, Nicolas

    2005-01-01

    Our study demonstrates that US color Doppler is a non invasive, reliable and reproducible method for the evaluation of the orbitary flow in normal and glaucomatous patients. However is suggested that every group evaluates the inter and intraobserver variability because of the lack of universal reference velocity measurements

  15. Aerosol distribution measurements by laser - Doppler - spectroscopy

    International Nuclear Information System (INIS)

    Baldassari, J.

    1977-01-01

    Laser-Doppler-Spectroscopy is used to study particle size distribution, especially sodium aerosols, in the presence of uncondensable gases. Theoretical basis are given, and an experimental technique is described. First theoretical results show reasonably good agreement with experimental data available; this method seems to be a promising one. (author)

  16. Laser Doppler thermometry in flat flames

    NARCIS (Netherlands)

    Maaren, van A.; Goey, de L.P.H.

    1994-01-01

    Laser Doppler Velocimetry measurements are performed in flat flames, stabilized on a newly developed flat-flame burner. It is shown that the velocity component perpendicular to the main flow direction, induced by expansion in the reaction zone and buoyancy in the burnt gas, is significant. A method

  17. Particle sizing experiments with the laser Doppler velocimeter: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Giel, T.V. Jr.; Son, J.Y.

    1988-06-01

    Measurement techniques for in-situ simultaneous measurements of particle size distributions and particle velocities using the dual beam laser Doppler velocimeter (LV) were analytically and experimentally investigated. This investigation examined the different signal characteristics of the LV for determination of particle size and particle velocity, simultaneously. The different size related signal components were evaluated not only singularly but also as simultaneous measurements to determine which characteristic, or combination of characteristics, provided the best measure of particle size. The evaluation concentrated on the 0.5 to 5 ..mu..m particle size range, in which the LV light scattering characteristics are complex often non-monotonic functions of the particle size as well as functions of index of refraction, the laser light wavelength, laser intensity and polarization, and the location and response characteristics of the detector. Different components of the LV signal were considered, but analysis concentrated on Doppler phase, visibility and scatter-intensity because they show the greatest promise. These signals characteristics were initially defined analytically for numerous optical configurations over the 0.5 to 5 ..mu..m diameter range with 0.1 ..mu..m segmentation, for refractive index values from 1.0 to 3.0 with absorptive (imaginary) components varied form 0 to 1.0. Collector orientation and effective f/No., as well as fringe spacing, beam polarization and wavelength, were varied in this analytical evaluation. 18 refs., 42 figs., 5 tabs.

  18. Two Component Decomposition of Dual Polarimetric HH/VV SAR Data: Case Study for the Tundra Environment of the Mackenzie Delta Region, Canada

    Directory of Open Access Journals (Sweden)

    Tobias Ullmann

    2016-12-01

    Full Text Available This study investigates a two component decomposition technique for HH/VV-polarized PolSAR (Polarimetric Synthetic Aperture Radar data. The approach is a straight forward adaption of the Yamaguchi decomposition and decomposes the data into two scattering contributions: surface and double bounce under the assumption of a negligible vegetation scattering component in Tundra environments. The dependencies between the features of this two and the classical three component Yamaguchi decomposition were investigated for Radarsat-2 (quad and TerraSAR-X (HH/VV data for the Mackenzie Delta Region, Canada. In situ data on land cover were used to derive the scattering characteristics and to analyze the correlation among the PolSAR features. The double bounce and surface scattering features of the two and three component scattering model (derived from pseudo-HH/VV- and quad-polarized data showed similar scattering characteristics and positively correlated-R2 values of 0.60 (double bounce and 0.88 (surface scattering were observed. The presence of volume scattering led to differences between the features and these were minimized for land cover classes of low vegetation height that showed little volume scattering contribution. In terms of separability, the quad-polarized Radarsat-2 data offered the best separation of the examined tundra land cover types and will be best suited for the classification. This is anticipated as it represents the largest feature space of all tested ones. However; the classes “wetland” and “bare ground” showed clear positions in the feature spaces of the C- and X-Band HH/VV-polarized data and an accurate classification of these land cover types is promising. Among the possible dual-polarization modes of Radarsat-2 the HH/VV was found to be the favorable mode for the characterization of the aforementioned tundra land cover classes due to the coherent acquisition and the preserved co-pol. phase. Contrary, HH/HV-polarized and VV

  19. Measurement of ciliary beat frequency using Doppler optical coherence tomography.

    Science.gov (United States)

    Lemieux, Bryan T; Chen, Jason J; Jing, Joseph; Chen, Zhongping; Wong, Brian J F

    2015-11-01

    Measuring ciliary beat frequency (CBF) is a technical challenge and difficult to perform in vivo. Doppler optical coherence tomography (D-OCT) is a mesoscopic noncontact imaging modality that provides high-resolution tomographic images and detects micromotion simultaneously in living tissues. In this work we used D-OCT to measure CBF in ex vivo tissue as the first step toward translating this technology to clinical use. Fresh ex vivo samples of rabbit tracheal mucosa were imaged using both D-OCT and phase-contrast microscopy (n = 5). The D-OCT system was designed and built to specification in our lab (1310-nm swept source vertical-cavity surface-emitting laser [VCSEL], 6-μm axial resolution). The samples were placed in culture and incubated at 37°C. A fast Fourier transform was performed on the D-OCT signal recorded on the surface of the samples to gauge CBF. High-speed digital video of the epithelium recorded via phase-contrast microscopy was analyzed to confirm the CBF measurements. The D-OCT system detected Doppler signal at the epithelial layer of ex vivo rabbit tracheal samples suggestive of ciliary motion. CBF was measured at 9.36 ± 1.22 Hz using D-OCT and 9.08 ± 0.48 Hz using phase-contrast microscopy. No significant differences were found between the 2 methods (p > 0.05). D-OCT allows for the quantitative measurement of CBF without the need to resolve individual cilia. Furthermore, D-OCT technology can be incorporated into endoscopic platforms that allow clinicians to readily measure CBF in the office and provide a direct measurement of mucosal health. © 2015 ARS-AAOA, LLC.

  20. TCSP ER-2 DOPPLER RADAR (EDOP) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The TCSP ER-2 DOPPLER RADAR (EDOP) dataset was collected by the ER-2 Doppler radar (EDOP), which is an X-band (9.6 GHz) Doppler radar mounted in the nose of the ER-2...

  1. CAMEX-4 ER-2 DOPPLER RADAR V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The CAMEX-4 ER-2 Doppler Radar dataset was collected by the ER-2 Doppler radar (EDOP), which is an X-band (9.6 GHz) Doppler radar mounted in the nose of ER-2. The...

  2. Radar micro-doppler signatures processing and applications

    CERN Document Server

    Chen, Victor C; Miceli, William J

    2014-01-01

    Radar Micro-Doppler Signatures: Processing and applications concentrates on the processing and application of radar micro-Doppler signatures in real world situations, providing readers with a good working knowledge on a variety of applications of radar micro-Doppler signatures.

  3. A two-component model of host–parasitoid interactions: determination of the size of inundative releases of parasitoids in biological pest contro

    NARCIS (Netherlands)

    Grasman, J.; Herwaarden, van O.A.; Hemerik, L.; Lenteren, van J.C.

    2001-01-01

    A two-component differential equation model is formulated for a host–parasitoid interaction. Transient dynamics and population crashes of this system are analysed using differential inequalities. Two different cases can be distinguished: either the intrinsic growth rate of the host population is

  4. The oligomeric assembly of the novel haem-degrading protein HbpS is essential for interaction with its cognate two-component sensor kinase

    NARCIS (Netherlands)

    Ortiz de Orué Lucana, Darío; Bogel, Gabriele; Zou, Peijian; Groves, Matthew R

    2009-01-01

    HbpS, a novel protein of previously unknown function from Streptomyces reticuli, is up-regulated in response to haemin- and peroxide-based oxidative stress and interacts with the SenS/SenR two-component signal transduction system. In this study, we report the high-resolution crystal structures (2.2

  5. Rhodococcus rhodochrous DSM 43269 3-Ketosteroid 9 alpha-Hydroxylase, a Two-Component Iron-Sulfur-Containing Monooxygenase with Subtle Steroid Substrate Specificity

    NARCIS (Netherlands)

    Petrusma, M.; Dijkhuizen, L.; van der Geize, R.

    2009-01-01

    This paper reports the biochemical characterization of a purified and reconstituted two-component 3-ketosteroid 9 alpha-hydroxylase (KSH). KSH of Rhodococcus rhodochrous DSM 43269, consisting of a ferredoxin reductase (KshB) and a terminal oxygenase (KshA), was heterologously expressed in

  6. Doppler speedometer for micro-organisms

    International Nuclear Information System (INIS)

    Penkov, F.; Tuleushev, A.; Lisitsyn, V.; Kim, S.; Tuleushev, Yu.

    1996-01-01

    Objective of Investigations: Development and creation of the Doppler speedometer for micro-organisms which allows to evaluate, in a real temporal scale, variations in the state of water suspension of micro-organisms under the effect of chemical, physical and other external actions. Statement of the Problem The main problem is absence of reliable, accessible for users and simple, in view of application, Doppler speedometers for micro-organisms. Nevertheless, correlation Doppler spectrometry in the regime of heterodyning the supporting and cell-scattered laser radiation is welt known. The main idea is that the correlation function of photo-current pulses bears an information on the averages over the assembly of cell velocities. For solving the biological problems, construction of auto-correlation function in the real-time regime with the delay time values comprising, function in the real-time regime with the delay time values comprising, nearly, 100 me (10 khz) or higher is needed. Computers of high class manage this problem using but the program software. Due to this, one can simplify applications of the proposed techniques provided he creates the Doppler speedometer for micro-organism on a base of the P entium . Expected Result Manufactured operable mock-up of the Doppler speedometer for micro-organisms in a form of the auxiliary computer block which allows to receive an information, in the real time scale, on the results of external effects of various nature on the cell assembly in transparent medium with a small volume of the studied cell suspension

  7. Poststenotic flow disturbance in the dog aorta as measured with pulsed Doppler ultrasound.

    Science.gov (United States)

    Talukder, N; Fulenwider, J T; Mabon, R F; Giddens, D P

    1986-08-01

    Blood flow velocity was measured in the dog aorta distal to mechanically induced constrictions of various degrees of severity employing an 8-MHz pulsed Doppler ultrasound velocimeter and a phase-lock loop frequency tracking method for extracting velocity from the Doppler quadrature signals. The data were analyzed to construct ensemble average velocity waveforms and random velocity disturbances. In any individual animal the effect of increasing the degree of stenosis beyond approximately 25 percent area reduction was to produce increasing levels of random velocity disturbance. However, variability among animals was such that the sensitivity of random behavior to the degree of stenosis was degraded to the point that it appears difficult to employ Doppler ultrasound measurements of random disturbances to discriminate among stenoses with area reductions less than approximately 75 percent. On the other hand, coherent vortex structures in velocity waveforms consistently occurred distal to mild constrictions (25-50 percent area reduction). Comparison of the phase-lock loop Doppler ultrasound data with simultaneous measurements using invasive hot-film anemometry, which possesses excellent frequency response, demonstrates that the ultrasound method can reliably detect those flow phenomena in such cases. Thus, the identification of coherent, rather than random, flow disturbances may offer improved diagnostic capability for noninvasively detecting arteriosclerotic plaques at relatively early stages of development.

  8. Planetary Radio Interferometry and Doppler Experiment (PRIDE) for Planetary Atmospheric Studies

    Science.gov (United States)

    Bocanegra Bahamon, Tatiana; Cimo, Giuseppe; Duev, Dmitry; Gurvits, Leonid; Molera Calves, Guifre; Pogrebenko, Sergei

    2015-04-01

    The Planetary Radio Interferometry and Doppler Experiment (PRIDE) is a technique that allows the determination of the radial velocity and lateral coordinates of planetary spacecraft with very high accuracy (Duev, 2012). The setup of the experiment consists of several ground stations from the European VLBI Network (EVN) located around the globe, which simultaneously perform Doppler tracking of a spacecraft carrier radio signal, and are subsequently processed in a VLBI-style in phase referencing mode. Because of the accurate examination of the changes in phase and amplitude of the radio signal propagating from the spacecraft to the multiple stations on Earth, the PRIDE technique can be used for several fields of planetary research, among which planetary atmospheric studies, gravimetry and ultra-precise celestial mechanics of planetary systems. In the study at hand the application of this technique for planetary atmospheric investigations is demonstrated. As a test case, radio occultation experiments were conducted with PRIDE having as target ESA's Venus Express, during different observing sessions with multiple ground stations in April 2012 and March 2014. Once each of the stations conducts the observation, the raw data is delivered to the correlation center at the Joint Institute for VLBI in Europe (JIVE) located in the Netherlands. The signals are processed with a high spectral resolution and phase detection software package from which Doppler observables of each station are derived. Subsequently the Doppler corrected signals are correlated to derive the VLBI observables. These two sets of observables are used for precise orbit determination. The reconstructed orbit along with the Doppler observables are used as input for the radio occultation processing software, which consists of mainly two modules, the geometrical optics module and the ray tracing inversion module, from which vertical density profiles, and subsequently, temperature and pressure profiles of Venus

  9. Comparison of Three Methods in Extracting Coherent Modes from a Doppler Backscatter System

    International Nuclear Information System (INIS)

    Zhang Xiao-Hui; Liu A-Di; Zhou Chu; Hu Jian-Qiang; Wang Ming-Yuan; Yu Chang-Xuan; Liu Wan-Dong; Li Hong; Lan Tao; Xie Jin-Lin

    2015-01-01

    We compare three different methods to extract coherent modes from Doppler backscattering (DBS), which are center of gravity (COG) of the complex amplitude spectrum, spectrum of DBS phase derivative (phase derivative method), and phase spectrum, respectively. These three methods are all feasible to extract coherent modes, for example, geodesic acoustic mode oscillation. However, there are still differences between dealing with high frequency modes (several hundred kHz) and low frequency modes (several kHz) hiding in DBS signal. There is a significant amount of power at low frequencies in the phase spectrum, which can be removed by using the phase derivative method and COG. High frequency modes are clearer by using the COG and the phase derivative method than the phase spectrum. The spectrum of DBS amplitude does not show the coherent modes detected by using COG, phase derivative method and phase spectrum. When two Doppler shifted peaks exist, coherent modes and their harmonics appear in the spectrum of DBS amplitude, which are introduced by the DBS phase. (paper)

  10. The medical Doppler in hand surgery: its scientific basis, applications, and the history of its namesake, Christian Johann Doppler.

    Science.gov (United States)

    Ghori, Ahmer K; Chung, Kevin C

    2007-12-01

    The word Doppler is used synonymously in hand surgery for evaluating patency of vascular structures; however, the science and history behind the Doppler effect are not as well-known. We will present the theories behind the Doppler effect and the history of the person who made this discovery.

  11. An ocean current inversion accuracy analysis based on a Doppler spectrum model

    Institute of Scientific and Technical Information of China (English)

    BAO Qingliu; ZHANG Youguang; LIN Mingsen; GONG Peng

    2017-01-01

    Microwave remote sensing is one of the most useful methods for observing the ocean parameters.The Doppler frequency or interferometric phase of the radar echoes can be used for an ocean surface current speed retrieval,which is widely used in spaceborne and airborne radars.While the effect of the ocean currents and waves is interactional.It is impossible to retrieve the ocean surface current speed from Doppler frequency shift directly.In order to study the relationship between the ocean surface current speed and the Doppler frequency shift,a numerical ocean surface Doppler spectrum model is established and validated with a reference.The input parameters of ocean Doppler spectrum include an ocean wave elevation model,a directional distribution function,and wind speed and direction.The suitable ocean wave elevation spectrum and the directional distribution function are selected by comparing the ocean Doppler spectrum in C band with an empirical geophysical model function (CDOP).What is more,the error sensitivities of ocean surface current speed to the wind speed and direction are analyzed.All these simulations are in Ku band.The simulation results show that the ocean surface current speed error is sensitive to the wind speed and direction errors.With VV polarization,the ocean surface current speed error is about 0.15 m/s when the wind speed error is 2 m/s,and the ocean surface current speed error is smaller than 0.3 m/s when the wind direction error is within 20° in the cross wind direction.

  12. Compact Transcranial Doppler (TCD) for Bioastronautics Research, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Returning men to the Moon and manned Mars missions will require advanced bioastronanutics research. One possible risk is Decompression Sickness (DCS) resulting from...

  13. Wide angle Michelson Doppler imaging interferometer. [measuring atmospheric emissions

    Science.gov (United States)

    Shepherd, G. G.

    1980-01-01

    The optical system, stepping control, phase and modulation depth, array detector, and directions sensor are described for a specialized type of Michelson interferometer which works at sufficiently high resolution to measure the line widths and Doppler shifts of naturally occurring atmospheric emissions. With its imaging capability, the instrument can potentially supply this data independently for each element of the 100 x 100 detector array. The experiment seeks: (1) to obtain vertical profiles of atmospheric winds and temperatures as functions of latitude by observing near the limb; (2) to acquire exploratory wind and temperature data on smaller scale structures in airglow irregularities and in auroral forms; and (3) to collaborate with other Spacelab experiments, such as barium cloud releases, in providing wind and temperature data.

  14. Power and color Doppler ultrasound settings for inflammatory flow

    DEFF Research Database (Denmark)

    Torp-Pedersen, Søren; Christensen, Robin; Szkudlarek, Marcin

    2015-01-01

    OBJECTIVE: To determine how settings for power and color Doppler ultrasound sensitivity vary on different high- and intermediate-range ultrasound machines and to evaluate the impact of these changes on Doppler scoring of inflamed joints. METHODS: Six different types of ultrasound machines were used....... On each machine, the factory setting for superficial musculoskeletal scanning was used unchanged for both color and power Doppler modalities. The settings were then adjusted for increased Doppler sensitivity, and these settings were designated study settings. Eleven patients with rheumatoid arthritis (RA......) with wrist involvement were scanned on the 6 machines, each with 4 settings, generating 264 Doppler images for scoring and color quantification. Doppler sensitivity was measured with a quantitative assessment of Doppler activity: color fraction. Higher color fraction indicated higher sensitivity. RESULTS...

  15. Transcranial Doppler sonography in familial hemiplegic migraine

    International Nuclear Information System (INIS)

    Pierelli, F.; Pauri, F.; Cupini, L.M.; Fiermonte, G.; Rizzo, P.A.

    1991-01-01

    A patient affected by familial hemiplegic migraine underwent transcranial Doppler sonography twice: the first during a spontaneous attack with right hemiparesis and aphasia, the second during a headachefree period. During the attack the following haemodynamic changes were seen: (a) bilateral increase in the middle cerebral artery and anterior cerebral artery blood flow velocities (this increase was more pronounced on the left side), (b) decreased systo-diastolic ratio and pulsatility index on the right side, (c) increased systo-diastolic ratio and pulsatility index on the left side. The results indicate that during the attack in this familial hemiplegic migraine patient, a diffuse vasoconstriction of the basal cerebral arteries developed. Moreover, transcranial Doppler sonography data suggest that a prolonged vasoconstriction of the peripheral arterioles could play a role in determining the neurological symptoms in this syndrome. 13 refs., 1 figs., 1 tab

  16. Color Doppler US of the penis

    Energy Technology Data Exchange (ETDEWEB)

    Bertolotto, Michele (ed.) [Trieste Univ. Ospedale di Cattinara (Italy). Dept. Radiology

    2008-07-01

    This book provides a comprehensive reference and practical guide on the application of US to penile diseases and conditions. After introductory chapters on technical requirements and penile anatomy, subsequent chapters offer a systematic overview of the diverse applications of color Doppler US. The topics covered include erectile dysfunction, Peyronie's disease, priapism, trauma, tumors, the postoperative penis, inflammation, and fibrosis. Each topic is introduced by a clinical overview with the purpose of clarifying the problems and elucidating what the urologist may expect from color Doppler US. Thereafter, performance of the US study is explained and the pathological anatomy reviewed. High-quality images obtained with high-end US equipment are included. Each chapter also contains a section on the diagnostic information provided by other imaging modalities, and in particular MRI. (orig.)

  17. Transcranial Doppler sonography in familial hemiplegic migraine

    Energy Technology Data Exchange (ETDEWEB)

    Pierelli, F.; Pauri, F.; Cupini, L.M.; Fiermonte, G.; Rizzo, P.A. (Universita la Sapienza, Roma (Italy))

    1991-02-01

    A patient affected by familial hemiplegic migraine underwent transcranial Doppler sonography twice: the first during a spontaneous attack with right hemiparesis and aphasia, the second during a headachefree period. During the attack the following haemodynamic changes were seen: (a) bilateral increase in the middle cerebral artery and anterior cerebral artery blood flow velocities (this increase was more pronounced on the left side), (b) decreased systo-diastolic ratio and pulsatility index on the right side, (c) increased systo-diastolic ratio and pulsatility index on the left side. The results indicate that during the attack in this familial hemiplegic migraine patient, a diffuse vasoconstriction of the basal cerebral arteries developed. Moreover, transcranial Doppler sonography data suggest that a prolonged vasoconstriction of the peripheral arterioles could play a role in determining the neurological symptoms in this syndrome. 13 refs., 1 figs., 1 tab.

  18. Renal duplex Doppler ultrasound findings in diabetics

    International Nuclear Information System (INIS)

    Shim, Hyang Yee; Kim, Young Geun; Kook, Cheol Keu; Yoon, Chong Hyun; Lee, Shin Hyung; Lee, Chang Joon

    1993-01-01

    The correlation between clinical-laboratory findings and renal duplex Doppler ultrasound findings was studied in 45 patients with diabetes mellitus to see the role of duplex Doppler ultrasound in the detection of diabetic nephropathy. The resistive indices in patients with elevated serum creatinine, BUN, proteinuria, and systolic blood pressure levels were statistically significantly higher than those in patients with normal levels (p<0.05). Also resistive indics in patients with retinopathy were higher than that in patients without retinopathy (p<0.05). But the ultrasound morphologic changes of kidney such as renal length, cortical eye-catching, and corticomedullarycontrast were not well correlated with clinical-laboratory data and resistive index. The resistive index of the kidney in conjunction with clinical-laboratory data in diabetics may be helpful in the evaluation of diabetic nephropathy

  19. Renal duplex Doppler ultrasound findings in diabetics

    Energy Technology Data Exchange (ETDEWEB)

    Shim, Hyang Yee; Kim, Young Geun; Kook, Cheol Keu; Yoon, Chong Hyun; Lee, Shin Hyung; Lee, Chang Joon [National Medical Center, Seoul (Korea, Republic of)

    1993-12-15

    The correlation between clinical-laboratory findings and renal duplex Doppler ultrasound findings was studied in 45 patients with diabetes mellitus to see the role of duplex Doppler ultrasound in the detection of diabetic nephropathy. The resistive indices in patients with elevated serum creatinine, BUN, proteinuria, and systolic blood pressure levels were statistically significantly higher than those in patients with normal levels (p<0.05). Also resistive indics in patients with retinopathy were higher than that in patients without retinopathy (p<0.05). But the ultrasound morphologic changes of kidney such as renal length, cortical eye-catching, and corticomedullarycontrast were not well correlated with clinical-laboratory data and resistive index. The resistive index of the kidney in conjunction with clinical-laboratory data in diabetics may be helpful in the evaluation of diabetic nephropathy

  20. Colour Doppler ultrasound of the penis

    Energy Technology Data Exchange (ETDEWEB)

    Wilkins, C.J.; Sriprasad, S.; Sidhu, P.S. E-mail: paulsidhu@compuserve.com

    2003-07-01

    Because it is a superficial structure, the penis is ideally suited to ultrasound imaging. A number of disease processes, including Peyronie's disease, penile fractures and penile tumours, are clearly visualized with ultrasound. An assessment of priapism can also be made using spectral Doppler waveform technology. Furthermore, dynamic assessment of cavernosal arterial changes after pharmaco-stimulation allows diagnosis of arterial and venogenic causes for impotence. This pictorial review illustrates the range of diseases encountered with ultrasound of the penis.

  1. Doppler Lidar Wind Value-Added Product

    Energy Technology Data Exchange (ETDEWEB)

    Newsom, R. K. [DOE ARM Climate Research Facility, Washington, DC (United States); Sivaraman, C. [DOE ARM Climate Research Facility, Washington, DC (United States); Shippert, T. R. [DOE ARM Climate Research Facility, Washington, DC (United States); Riihimaki, L. D. [DOE ARM Climate Research Facility, Washington, DC (United States)

    2015-07-01

    Wind speed and direction, together with pressure, temperature, and relative humidity, are the most fundamental atmospheric state parameters. Accurate measurement of these parameters is crucial for numerical weather prediction. Vertically resolved wind measurements in the atmospheric boundary layer are particularly important for modeling pollutant and aerosol transport. Raw data from a scanning coherent Doppler lidar system can be processed to generate accurate height-resolved measurements of wind speed and direction in the atmospheric boundary layer.

  2. A Two-Component Regulatory System, CsrR-CsrS, Represses Expression of Three Streptococcus pyogenes Virulence Factors, Hyaluronic Acid Capsule, Streptolysin S, and Pyrogenic Exotoxin B

    OpenAIRE

    Heath, Andrew; DiRita, Victor J.; Barg, Neil L.; Engleberg, N. Cary

    1999-01-01

    Certain Tn916 insertions in the chromosome of an M1-type, nonmucoid Streptococcus pyogenes isolate (MGAS166) were previously shown to result in stable mucoidy with increased expression of the capsular synthetic genes. The transposon insertions in these strains are directly upstream of an apparent operon encoding a two-component regulatory system, designated csrR-csrS. Compared with MGAS166, these mucoid mutants are more hemolytic and cause significantly more tissue damage in a murine model of...

  3. The Pathophysiology of Decompression Sickness and the Effects of Doppler Detectable Bubbles.

    Science.gov (United States)

    1980-12-18

    workers (Harvey, 1951a and 1951b) and Blinks, Twitty and Whiteker (1951) show that muscular activity was a 23 ~I. predisposing factor to the formation of...Hills, 1966), the mechanism of action is somewhat specific (neural distension ); but for those theories utilizing circulation and/or intravascular...highly perfused non- muscular tissue, such as kidney, forms a gas phase following decompression, Doppler perivascular cuff probes were surgically placed on

  4. Six-beam homodyne laser Doppler vibrometry based on silicon photonics technology.

    Science.gov (United States)

    Li, Yanlu; Zhu, Jinghao; Duperron, Matthieu; O'Brien, Peter; Schüler, Ralf; Aasmul, Soren; de Melis, Mirko; Kersemans, Mathias; Baets, Roel

    2018-02-05

    This paper describes an integrated six-beam homodyne laser Doppler vibrometry (LDV) system based on a silicon-on-insulator (SOI) full platform technology, with on-chip photo-diodes and phase modulators. Electronics and optics are also implemented around the integrated photonic circuit (PIC) to enable a simultaneous six-beam measurement. Measurement of a propagating guided elastic wave in an aluminum plate (speed ≈ 909 m/s @ 61.5 kHz) is demonstrated.

  5. Spatially Resolved MR-Compatible Doppler Ultrasound: Proof of Concept for Triggering of Diagnostic Quality Cardiovascular MRI for Function and Flow Quantification at 3T.

    Science.gov (United States)

    Crowe, Lindsey Alexandra; Manasseh, Gibran; Chmielewski, Aneta; Hachulla, Anne-Lise; Speicher, Daniel; Greiser, Andreas; Muller, Hajo; de Perrot, Thomas; Vallee, Jean-Paul; Salomir, Rares

    2018-02-01

    We demonstrate the use of a magnetic-resonance (MR)-compatible ultrasound (US) imaging probe using spatially resolved Doppler for diagnostic quality cardiovascular MR imaging (MRI) as an initial step toward hybrid US/MR fetal imaging. A newly developed technology for a dedicated MR-compatible phased array ultrasound-imaging probe acquired pulsed color Doppler carotid images, which were converted in near-real time to a trigger signal for cardiac cine and flow quantification MRI. Ultrasound and MR data acquired simultaneously were interference free. Conventional electrocardiogram (ECG) and the proposed spatially resolved Doppler triggering were compared in 10 healthy volunteers. A synthetic "false-triggered" image was retrospectively processed using metric optimized gating (MOG). Images were scored by expert readers, and sharpness, cardiac function and aortic flow were quantified. Four-dimensional (4-D) flow (two volunteers) showed feasibility of Doppler triggering over a long acquisition time. Imaging modalities were compatible. US probe positioning was stable and comfortable. Image quality scores and quantified sharpness were statistically equal for Doppler- and ECG-triggering (p ). ECG-, Doppler-triggered, and MOG ejection fractions were equivalent (p ), with false-triggered values significantly lower (p 0.05). 4-D flow quantification gave consistent results between ECG and Doppler triggering. We report interference-free pulsed color Doppler ultrasound during MR data acquisition. Cardiovascular MRI of diagnostic quality was successfully obtained with pulsed color Doppler triggering. The hardware platform could further enable advanced free-breathing cardiac imaging. Doppler ultrasound triggering is applicable where ECG is compromised due to pathology or interference at higher magnetic fields, and where direct ECG is impossible, i.e., fetal imaging.

  6. A Comparison Study of Vector Velocity, Spectral Doppler and Magnetic Resonance of Blood Flow in the Common Carotid Artery

    DEFF Research Database (Denmark)

    Brandt, Andreas Hjelm; Hansen, Kristoffer Lindskov; Ewertsen, Caroline

    2018-01-01

    Magnetic resonance phase contrast angiography (MRA) is the gold standard for blood flow evaluation. Spectral Doppler ultrasound (SDU) is the first clinical choice, although the method is angle dependent. Vector flow imaging (VFI) is an angle-independent ultrasound method. The aim of the study...

  7. Evaluation of a multimode fiber optic low coherence interferometer for path length resolved Doppler measurments of diffuse light

    NARCIS (Netherlands)

    Varghese, Babu; Rajan, Vinayakrishnan; van Leeuwen, Ton; Steenbergen, Wiendelt

    2007-01-01

    The performance of a graded index multimode fiber optic low coherence Mach-Zehnder interferometer with phase modulation is analyzed. Investigated aspects were its ability to measure path length distributions and to perform path length resolved Doppler measurements of multiple scattered photons in a

  8. Evaluation of a multimode fiber optic low coherence interferometer for path length resolved Doppler measurements of diffuse light

    NARCIS (Netherlands)

    Varghese, Babu; Rajan, Vinayakrishnan; van Leeuwen, Ton G.; Steenbergen, Wiendelt

    2007-01-01

    The performance of a graded index multimode fiber optic low coherence Mach-Zehnder interferometer with phase modulation is analyzed. Investigated aspects were its ability to measure path length distributions and to perform path length resolved Doppler measurements of multiple scattered photons in a

  9. Recommendations for terminology and display for doppler echocardiography

    International Nuclear Information System (INIS)

    Anon.

    1986-01-01

    Doppler echocardiography has recently emerged as a major noninvasive technique with many applications in cardiology. To a large extent, this has been based upon a combination of clinical and engineering advances which now make possible the use of quantitative Doppler echocardiography in combination with two-dimensional imaging for measurement of volume flows, transvalve gradients, and other physiologic flow parameters which reflect cardiac function. It was the purpose of this Committee to provide a glossary of terms which could be used in standard fashion for papers and discussions related to Doppler echocardiography. As part of its task, the Committee also undertook an attempt to recommend a standard for display of Doppler information which would be useful, both for manufacturers and for clinicians. The document, therefore, includes: Section I, the Committee's recommendations for Doppler display. Section II, the glossary of Doppler terms, related to engineering and to clinical applications

  10. The image of urachus adenocarcinoma on Doppler ultrasonography

    Energy Technology Data Exchange (ETDEWEB)

    Oyar, Orhan E-mail: o_oyar@hotmail.com; Yesildag, Ahmet; Gulsoy, Ufuk Kemal; Perk, Hakki

    2002-10-01

    Malignant urachal lesions are exceedingly rare and occur predominantly in adult life. In this case report, an adult patient with urachal carcinoma is presented with abdominal plain film, intravenous urography, gray-scale ultrasonography (US), Doppler US, and computed tomography (CT). Doppler US successfully showed the neovascularity with low resistive index value in the urachus tumor. We believe that Doppler US examination is helpful in the differential diagnosis of urachal carcinoma.

  11. Doppler US evaluation of the hypertensive portal system

    International Nuclear Information System (INIS)

    Needleman, L.; Kurtz, A.B.; Bezzi, M.; Rifkin, M.D.; Pasto, M.E.; Pennell, R.G.; Baltarowich, O.H.; Goldberg, B.B.

    1986-01-01

    In patients with known portal hypertension, pulsed Doppler US was used for qualitative and directional evaluation of flow in the portal venous system and collateral vessels. Most patients had normal hepatopetal flow. Doppler US revealed the following abnormal blood flow patterns: hepatofugal portal flow, bidirectional portal flow, intrahepatic portal shunting, flow in portasystemic collaterals, and hepatic vein obstruction. Doppler US can provide important clinical information in the evaluation of portal hypertension

  12. New Insights from Inside-Out Doppler Tomography

    Directory of Open Access Journals (Sweden)

    E. J. Kotze

    2015-02-01

    Full Text Available We present preliminary results from our investigation into using an “inside-out” velocity space for creating a Doppler tomogram. The aim is to transpose the inverted appearance of the Cartesian velocity space used in normal Doppler tomography. In a comparison between normal and inside-out Doppler tomograms of cataclysmic variables, we show that the inside-out velocity space has the potential to produce new insights into the accretion dynamics in these systems.

  13. Power doppler 'blanching' after the application of transducer pressure

    International Nuclear Information System (INIS)

    Joshua, F.; Edmonds, J.; Lassere, M.; De Carle, R.; Rayment, M.; Bryant, C.; Shnier, R.

    2005-01-01

    The aim of this study was to determine if transducer pressure modifies power Doppler assessments of rheumatoid arthritis synovium at the metacarpophalangeal joints and metatarsophalangeal joints. Five rheumatoid arthritis patients of varying degrees of 'disease activity' and damage were assessed with power Doppler ultrasound scanning of the dominant hand second to fifth metacarpophalangeal joints. Two rheumatoid arthritis patients had their dominant foot first to fifth metatarsophalangeal joints assessed with power Doppler ultrasound. Ultrasonography was performed with a high frequency transducer (14 MHz) with a colour mode frequency of 10 Mhz, and a standard colour box and gain. In the joint that showed the highest power Doppler signal, an image was made. A further image was taken after transducer pressure was applied. In all patients, there was increased flow to at least one joint. After pressure was applied, power Doppler signal intensity markedly reduced in all images and in some there was no recordable power Doppler signal. Increased transducer pressure can result in a marked reduction or obliteration in power Doppler signal. This power Doppler 'blanching' shows the need for further studies to evaluate sources of error and standardization before power Doppler ultrasound becomes a routine measure of 'disease activity' in rheumatoid arthritis. Copyright (2005) Blackwell Science Pty Ltd

  14. Evaluating Peripheral Vascular Injuries: Is Color Doppler Enough for Diagnosis?

    Directory of Open Access Journals (Sweden)

    Mohd Lateef Wani

    2014-03-01

    Full Text Available Background:: Vascular injury poses a serious threat to limb and life. Thus, diagnosis should be made immediately with minimally invasive methods. Doppler is a good aid in diagnosis of vascular injury. Methods:: The present prospective study was conducted on 150 patients who presented with soft signs (the signs which are suggestive but not confirmatory of vascular injury. They were subjected to color Doppler examination before exploration. The patients with the features of vascular injury on color Doppler were subjected to exploration. On the other hand, those who had normal Doppler were subjected to CT- angiography. Then, the findings of the exploration were matched with those of color Doppler. The data were analyzed using the SPSS statistical software. Results:: Out of the 150 Doppler examinations, 110 (73.33% were reported as positive, while 40 were reported as negative for vascular injury. These were subjected to CT-angiography and seven of them had the features of vascular injury on CT-angiography. All the patients with positive Doppler or CT angiography findings were subjected to exploration. Doppler had a sensitivity of 94% and specificity of 82.5% in diagnosis of vascular injury using Binary classification test. Conclusions:: Color Doppler is an easily available, reliable, and handy method of diagnosing a vascular injury. It has a very high sensitivity and specificity in diagnosis of vascular injuries.

  15. A novel outer-membrane anion channel (porin) as part of a putatively two-component transport system for 4-toluenesulphonate in Comamonas testosteroni T-2

    OpenAIRE

    Mampel, Jörg; Maier, Elke; Tralau, Tewes; Ruff, Jürgen; Benz, Roland; Cook, Alasdair M.

    2004-01-01

    Inducible mineralization of TSA (4-toluenesulphonate) by Comamonas testosteroni T-2 is initiated by a secondary transport system, followed by oxygenation and oxidation by TsaMBCD to 4-sulphobenzoate under the regulation of TsaR and TsaQ. Evidence is presented for a novel, presumably two-component transport system (TsaST). It is proposed that TsaT, an outer-membrane porin, formed an anion-selective channel that works in co-operation with the putative secondary transporter, TsaS, located in the...

  16. Coherent Detection in Laser Doppler Velocimeters

    DEFF Research Database (Denmark)

    Hanson, Steen Grüner

    1974-01-01

    , but intelligible particle picture of electromagnetic waves. The analysis is carried out with special emphasis on the heterodyning process in the laser Doppler velocimeter (LDV) because the main purpose of this article is to provide a better understanding of this instrument. An aid for this purpose......The possibility of heterodyning between electromagnetic waves scattered by particles separated in space is explained from a classical point of view and from a quantum mechanical point of view. The last description being carried out using only the Heisenberg uncertainty principle and a rather coarse...

  17. Digital setup for Doppler broadening spectroscopy

    International Nuclear Information System (INIS)

    Cizek, J; Vlcek, M; Prochazka, I

    2011-01-01

    New digital spectrometer for measurement of the Doppler shift of annihilation photons was developed and tested in this work. Digital spectrometer uses a fast 12-bit digitizer for direct sampling of signals from HPGe detectors. Analysis of sampled waveforms is performed off-line in software. Performance of the new digital setup was compared with its traditional analogue counterpart. Superior energy resolution was achieved in the digital setup. Moreover, the digital setup allows for a better control of the shape of detector signals. This enables to eliminate undesired signals damaged by pile-up effects or by ballistic deficit.

  18. Doppler shift simulation of scattered HF signals during the Tromsø HF pumping experiment on 16 February 1996

    Directory of Open Access Journals (Sweden)

    T. D. Borisova

    Full Text Available Comparisons between bistatic scatter measurements and simulation results during the Tromsø HF pumping experiment on 16 February 1996 are made. Doppler measurements of an HF diagnostic signal scattered from the field-aligned irregularities (FAIs in the auroral E-region were carried out on the London – Tromsø – St. Petersburg path at 9410 kHz from 21:00 to 22:00 UT. The scattered signals were observed both from natural and artificial ionospheric irregularities located in the vicinity of Tromsø. To simulate the Doppler frequency shifts, fd , of scattered signals, a radio channel model, named CONE, was developed. The model allows for ray tracing, group and phase paths, and Doppler frequency shift calculations. The calculated Doppler shifts were analyzed for dependence on the magnitude and direction of plasma velocities in the scattering volume. It was found that the velocity components in the north-south direction are crucial for explaining the Doppler frequency shifts of the scattered diagnostic signals. To simulate fd , real velocities obtained from the EISCAT UHF radar at an altitude of 278 km and from the digital all-sky imager during the experiment were employed. The simulation results of Doppler frequency shift variations with time are in reasonable agreement with the experimental Doppler shifts of scattered signals on the London – Tromsø – St. Petersburg path.

    Key words. Ionosphere (active experiments; ionospheric irregularities Radio science (ionospheric propagation

  19. The two-component spin-fermion model for high-Tc cuprates: its applications in neutron scattering and ARPES experiments

    International Nuclear Information System (INIS)

    Bang, Yunkyu

    2012-01-01

    Motivated by neutron scattering experiments in high-T c cuprates, we propose the two-component spin-fermion model as a minimal phenomenological model, which has both local spins and itinerant fermions as independent degrees of freedom (d.o.f.). Our calculations of the dynamic spin correlation function provide a successful description of the puzzling neutron experiment data and show that: (i) the upward dispersion branch of magnetic excitations is mostly due to local spin excitations; (ii) the downward dispersion branch is from collective particle-hole excitations of fermions; and (iii) the resonance mode is a mixture of both d.o.f. Using the same model with the same set of parameters, we calculated the renormalized quasiparticle (q.p.) dispersion and successfully reproduced one of the key features of the angle-resolved photoemission spectroscopy (ARPES) experiments, namely the high-energy kink structure in the fermion q.p. dispersion, thus supporting the two-component spin-fermion phenomenology. (paper)

  20. STED Imaging of Golgi Dynamics with Cer-SiR: A Two-Component, Photostable, High-Density Lipid Probe for Live Cells.

    Science.gov (United States)

    Erdmann, Roman S; Toomre, Derek; Schepartz, Alanna

    2017-01-01

    Long time-lapse super-resolution imaging in live cells requires a labeling strategy that combines a bright, photostable fluorophore with a high-density localization probe. Lipids are ideal high-density localization probes, as they are >100 times more abundant than most membrane-bound proteins and simultaneously demark the boundaries of cellular organelles. Here, we describe Cer-SiR, a two-component, high-density lipid probe that is exceptionally photostable. Cer-SiR is generated in cells via a bioorthogonal reaction of two components: a ceramide lipid tagged with trans-cyclooctene (Cer-TCO) and a reactive, photostable Si-rhodamine dye (SiR-Tz). These components assemble within the Golgi apparatus of live cells to form Cer-SiR. Cer-SiR is benign to cellular function, localizes within the Golgi at a high density, and is sufficiently photostable to enable visualization of Golgi structure and dynamics by 3D confocal or long time-lapse STED microscopy.

  1. I. A model for the magnetic equation of state of liquid 3He. II. An induced interaction model for a two-component Fermi liquid

    International Nuclear Information System (INIS)

    Sanchez-Castro, C.R.

    1988-01-01

    This dissertation is divided in six chapters. Chapter 1 is an introduction to the rest of the dissertation. In it, the author presents the different models for the magnetic equation state of liquid 3 He, a derivation of the induced interaction equations for a one component Fermi liquid, and discuss the basic hamiltonian describing the heavy fermion compounds. In Chapter 2 and Chapter 3, he presents a complete discussion of the thermodynamics and Landau theory of a spin polarized Fermi liquid. A phenomenological model is then developed to predict the polarization dependence of the longitudinal Landau parameters in liquid 3 He. This model predicts a new magnetic equation of state and the possibility of liquid 3 He being 'nearly metamagnetic' at high pressures. Chapter 4 contains a microscopic calculation of the magnetic field dependence of the Landau parameters in a strongly correlated Fermi system using the induced interaction model. The system he studied consists of a single component Fermi liquid with parabolic energy bands, and a large on-site repulsive interaction. In Chapter 5, he presents a complete discussion of the Landau theory of a two component Fermi liquid. Then, he generalizes the induced interaction equations to calculate Landau parameters and scattering amplitudes for an arbitrary, spin polarized, two component Fermi liquid. The resulting equations are used to study a model for the heavy fermion Fermi liquid state: a two band electronic system with an antiferromagnetic interaction between the two bands. Chapter 6 contains the concluding remarks of the dissertation

  2. Control of CydB and GltA1 expression by the SenX3 RegX3 two component regulatory system of Mycobacterium tuberculosis.

    Directory of Open Access Journals (Sweden)

    Gretta Roberts

    Full Text Available Two component regulatory systems are used widely by bacteria to coordinate changes in global gene expression profiles in response to environmental signals. The SenX3-RegX3 two component system of Mycobacterium tuberculosis has previously been shown to play a role in virulence and phosphate-responsive control of gene expression. We demonstrate that expression of SenX3-RegX3 is controlled in response to growth conditions, although the absolute changes are small. Global gene expression profiling of a RegX3 deletion strain and wild-type strain in different culture conditions (static, microaerobic, anaerobic, as well as in an over-expressing strain identified a number of genes with changed expression patterns. Among those were genes previously identified as differentially regulated in aerobic culture, including ald (encoding alanine dehydrogenase cyd,encoding a subunit of the cytochrome D ubiquinol oxidase, and gltA1, encoding a citrate synthase. Promoter activity in the upstream regions of both cydB and gltA1 was altered in the RegX3 deletion strain. DNA-binding assays confirmed that RegX3 binds to the promoter regions of ald, cydB and gltA1 in a phosphorylation-dependent manner. Taken together these data suggest a direct role for the SenX-RegX3 system in modulating expression of aerobic respiration, in addition to its role during phosphate limitation.

  3. Detection of Traveling Ionospheric Disturbances by Medium Frequency Doppler Sounding Using AM Radio Transmissions

    Science.gov (United States)

    Chilcote, M. A.; Labelle, J. W.; Lind, F. D.; Coster, A. J.; Galkin, I. A.; Miller, E.; Weatherwax, A. T.

    2013-12-01

    Nighttime traveling ionosphere disturbances (TIDs) propagating in the lower F region of the ionosphere were detected from time variations in the Doppler shifts of commercial AM radio broadcast stations. Three separately deployed receivers, components of the Intercepted Signals for Ionospheric Science (ISIS) Array software radio instrumentation network, recorded signals from two radio stations during eleven nights in March-April, 2012. Combining these measurements established that variations in the frequencies of the received signals, with amplitudes up to a few tenths of a Hertz, resulted from Doppler shifts produced by the ionosphere. At times, TIDs were detected as large amplitude variations in the Doppler shift with approximately 40-minute period correlated across the array. For one study interval, 0000-0400 UT on April 13, 2012, simultaneous GPS-TEC, digisonde, and superDARN coherent backscatter radar measurements confirmed the detection of TIDs with the same period. Detection of the AM signals at widely spaced receivers allowed the phase velocity and wavelength of the TIDs to be inferred, with some limitations due to differing reflection heights for the different frequencies. These measurements will be compared to phase velocities and wavelengths determined from combining an array of GPS receivers; discrepancies due to the altitude sensitivity of the techniques or other effects will be discussed. These results demonstrate that AM radio signals can be used for detection of nighttime TIDs.

  4. Ambiguity resolution for satellite Doppler positioning systems

    Science.gov (United States)

    Argentiero, P.; Marini, J.

    1979-01-01

    The implementation of satellite-based Doppler positioning systems frequently requires the recovery of transmitter position from a single pass of Doppler data. The least-squares approach to the problem yields conjugate solutions on either side of the satellite subtrack. It is important to develop a procedure for choosing the proper solution which is correct in a high percentage of cases. A test for ambiguity resolution which is the most powerful in the sense that it maximizes the probability of a correct decision is derived. When systematic error sources are properly included in the least-squares reduction process to yield an optimal solution the test reduces to choosing the solution which provides the smaller valuation of the least-squares loss function. When systematic error sources are ignored in the least-squares reduction, the most powerful test is a quadratic form comparison with the weighting matrix of the quadratic form obtained by computing the pseudoinverse of a reduced-rank square matrix. A formula for computing the power of the most powerful test is provided. Numerical examples are included in which the power of the test is computed for situations that are relevant to the design of a satellite-aided search and rescue system.

  5. Color Doppler Ultrasonographic Features of Hashimoto's Thyroiditis

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Joo Hyuk; Kim, Mie Young; Rho, Eun Jin; Yi, Jeong Geun; Han, Chun Hwan [Kangnam General Hospital Public Corporation, Seoul (Korea, Republic of); Hwang, Hee Yong [Choong Ang Gil Hospital, Incheon (Korea, Republic of)

    1995-06-15

    Color Doppler ultrasonographic(US) features of 28 patients with Hashimato's thyroiditis were evaluated with regard to echo and color-flow patterns. Correlation of color-flow pattern with thyroid function was performed. All 28 patients showed varying degrees of diffuse enlargement of the thyroid gland and a heterogeneous echo pattern.Color-flow pattern of increased blood flow. Low to moderate, focally increased blood flow was seen in 26 patients(92.8%). Of these 26 patients, 24 patients showed subclinical hypothyroidism or euthyroidism. Two patients who showed hyperthyroidism showed several pieces of focally increased color flow, Which was noted during both systole and diastole. Diffuse, multifocal color-flow throughout thyroid gland was seen in two patients with Hashimato's thyroiditis: one with clinical hypothyroidism and the other with subclinical hypothyroidism. Even though Hashimoto's thyroiditis showed variable color-flow patterns, we believe that heterogenous parenchymal echopattern with low or moderately increased flow is a rather characteristic feature of Hashimoto's thyroiditis, and we suggest that color Doppler US provides additional information for evaluation of Hashimoto's thyroiditis

  6. Enormous periodic doppler shifts in SS 433

    International Nuclear Information System (INIS)

    Margon, B.; Ford, H.C.; Grandi, S.A.; Stone, R.P.S.

    1979-01-01

    We have previously reported prominent ''moving' emission lines in the visible spectrum of Stephenson-Sanduleak 433, the optical counterpart of a variable radio and X-ray source. Further observations show that despite the implausible velocities and changes in velocities implied if the moving features are interpreted as Doppler-shifted Balmer lines, this explanation is indeed correct. Spectroscopy of SS 433 on 51 mights in 1978--1979 reveals that the unidentified features are two sets of Balmer and He I lines, one with large and changing redshift, and the other with large and changing blueshift. Combining our data with published earlier observations, we obtain Doppler shifts on 80 nights in the period 1978 June to 1979 June. These data indicate that the velocity variations are cyclical, repeating in both the blueshift and redshift systems with a period of 164 +- 3 days. The two systems have thus far been observed to reach maximum positive and negative radial velocities of +50,000 and -35,000 km s -1 , respectively, are always symmetric about redshift z=0.04, and follow roughly sinusoidal velocity curves. We discuss in addition a variety of interesting short-term spectroscopic details, including minor but highly significant deviations of the radial velocity from the sinusoid, and nightly line profile changes, sometimes appearing as mirror-image events in the redshift and blueshift systems. The behavior of SS 433 is unprecedented

  7. Parametric Investigation of Laser Doppler Microphones

    Science.gov (United States)

    Daoud, M.; Naguib, A.

    2002-11-01

    The concept of a Laser Doppler Microphone (LDM) is based on utilizing the Doppler frequency shift of a focused laser beam to measure the unsteady velocity of the center point of a flexible polymer diaphragm that is mounted on top of a hole and subjected to the unsteady pressure. Time integration of the velocity signal yields a time series of the diaphragm displacement, which can be converted to pressure from knowledge of the sensor's deflection sensitivity. In our APS/DFD presentation last year, the stringent frequency resolution requirement of these new sensors and methods to meet this requirement were discussed. Here, the dependence of the sensor characteristics (sensitivity, bandwidth, and noise floor) on various significant parameters is investigated in detail by calibrating the sensor in a plane wave tube in the frequency range of 50 - 5000 Hz. Parameters investigated include sensor diaphragm material and thickness, sensor size, damping of the diaphragm motion and laser beam spot size. The results shed light on the operating limits of the new sensor and demonstrate its ability to conduct high-spatial-resolution measurements in typical high-Reynolds-number test facilities. Moreover, calibrated LDM sensors were used to conduct measurements in a separating/reattaching flow and the results are compared to classical electret-type microphones with a similar sensing diameter.

  8. Color Doppler Ultrasonographic Features of Hashimoto's Thyroiditis

    International Nuclear Information System (INIS)

    Lee, Joo Hyuk; Kim, Mie Young; Rho, Eun Jin; Yi, Jeong Geun; Han, Chun Hwan; Hwang, Hee Yong

    1995-01-01

    Color Doppler ultrasonographic(US) features of 28 patients with Hashimato's thyroiditis were evaluated with regard to echo and color-flow patterns. Correlation of color-flow pattern with thyroid function was performed. All 28 patients showed varying degrees of diffuse enlargement of the thyroid gland and a heterogeneous echo pattern.Color-flow pattern of increased blood flow. Low to moderate, focally increased blood flow was seen in 26 patients(92.8%). Of these 26 patients, 24 patients showed subclinical hypothyroidism or euthyroidism. Two patients who showed hyperthyroidism showed several pieces of focally increased color flow, Which was noted during both systole and diastole. Diffuse, multifocal color-flow throughout thyroid gland was seen in two patients with Hashimato's thyroiditis: one with clinical hypothyroidism and the other with subclinical hypothyroidism. Even though Hashimoto's thyroiditis showed variable color-flow patterns, we believe that heterogenous parenchymal echopattern with low or moderately increased flow is a rather characteristic feature of Hashimoto's thyroiditis, and we suggest that color Doppler US provides additional information for evaluation of Hashimoto's thyroiditis

  9. Is Doppler ultrasound useful for evaluating gestational trophoblastic disease?

    Directory of Open Access Journals (Sweden)

    Lawrence H. Lin

    Full Text Available Doppler ultrasound is a non-invasive method for evaluating vascularization and is widely used in clinical practice. Gestational trophoblastic neoplasia includes a group of highly vascularized malignancies derived from placental cells. This review summarizes data found in the literature regarding the applications of Doppler ultrasound in managing patients with gestational trophoblastic neoplasia. The PubMed/Medline, Web of Science, Cochrane and LILACS databases were searched for articles published in English until 2014 using the following keywords: “Gestational trophoblastic disease AND Ultrasonography, Doppler.” Twenty-eight articles met the inclusion criteria and were separated into the 4 following groups according to the aim of the study. (1 Doppler ultrasound does not seem to be capable of differentiating partial from complete moles, but it might be useful when evaluating pregnancies in which a complete mole coexists with a normal fetus. (2 There is controversy in the role of uterine artery Doppler velocimetry in the prediction of development of gestational trophoblastic neoplasia. (3 Doppler ultrasound is a useful tool in the diagnosis of gestational trophoblastic neoplasia because abnormal myometrial vascularization and lower uterine artery Doppler indices seem to be correlated with invasive disease. (4 Lower uterine artery Doppler indices in the diagnosis of gestational trophoblastic neoplasia are associated with methotrexate resistance and might play a role in prognosis. CONCLUSION: Several studies support the importance of Doppler ultrasound in the management of patients with gestational trophoblastic neoplasia, particularly the role of Doppler velocimetry in the prediction of trophoblastic neoplasia and the chemoresistance of trophoblastic tumors. Doppler findings should be used as ancillary tools, along with human chorionic gonadotropin assessment, in the diagnosis of gestational trophoblastic neoplasia.

  10. Is Doppler ultrasound useful for evaluating gestational trophoblastic disease?

    Science.gov (United States)

    Lin, Lawrence H; Bernardes, Lisandra S; Hase, Eliane A; Fushida, Koji; Francisco, Rossana P V

    2015-12-01

    Doppler ultrasound is a non-invasive method for evaluating vascularization and is widely used in clinical practice. Gestational trophoblastic neoplasia includes a group of highly vascularized malignancies derived from placental cells. This review summarizes data found in the literature regarding the applications of Doppler ultrasound in managing patients with gestational trophoblastic neoplasia. The PubMed/Medline, Web of Science, Cochrane and LILACS databases were searched for articles published in English until 2014 using the following keywords: "Gestational trophoblastic disease AND Ultrasonography, Doppler." Twenty-eight articles met the inclusion criteria and were separated into the 4 following groups according to the aim of the study. (1) Doppler ultrasound does not seem to be capable of differentiating partial from complete moles, but it might be useful when evaluating pregnancies in which a complete mole coexists with a normal fetus. (2) There is controversy in the role of uterine artery Doppler velocimetry in the prediction of development of gestational trophoblastic neoplasia. (3) Doppler ultrasound is a useful tool in the diagnosis of gestational trophoblastic neoplasia because abnormal myometrial vascularization and lower uterine artery Doppler indices seem to be correlated with invasive disease. (4) Lower uterine artery Doppler indices in the diagnosis of gestational trophoblastic neoplasia are associated with methotrexate resistance and might play a role in prognosis. Several studies support the importance of Doppler ultrasound in the management of patients with gestational trophoblastic neoplasia, particularly the role of Doppler velocimetry in the prediction of trophoblastic neoplasia and the chemoresistance of trophoblastic tumors. Doppler findings should be used as ancillary tools, along with human chorionic gonadotropin assessment, in the diagnosis of gestational trophoblastic neoplasia.

  11. Broadband phase difference method for ultrasonic velocimetry in molten glass

    International Nuclear Information System (INIS)

    Kikura, Hiroshige; Ihara, Tomonori

    2016-01-01

    This study aims to develop ultrasonic Doppler velocimetry in molten glass. Realization of such a technique has two difficulties: ultrasonic transmission into molten salt and Doppler signal processing. Buffer rod technique was developed in our research to transmit ultrasound into high temperature molten glass. This article discusses newly developed signal processing technique named broadband phase difference method. (J.P.N.)

  12. A New Ka-Band Scanning Radar Facility: Polarimetric and Doppler Spectra Measurements of Snow Events

    Science.gov (United States)

    Oue, M.; Kollias, P.; Luke, E. P.; Mead, J.

    2017-12-01

    Polarimetric radar analyses offer the capability of identification of ice hydrometeor species as well as their spatial distributions. In addition to polarimetric parameter observations, Doppler spectra measurements offer unique insights into ice particle properties according to particle fall velocities. In particular, millimeter-wavelength radar Doppler spectra can reveal supercooled liquid cloud droplets embedded in ice precipitation clouds. A Ka-band scanning polarimetric radar, named KASPR, was installed in an observation facility at Stony Brook University, located 22 km west of the KOKX NEXRAD radar at Upton, NY. The KASPR can measure Doppler spectra and full polarimetric variables, including radar reflectivity, differential reflectivity (ZDR), differential phase (φDP), specific differential phase (KDP), correlation coefficient (ρhv), and linear depolarization ratio (LDR). The facility also includes a micro-rain radar and a microwave radiometer capable of measuring reflectivity profiles and integrated liquid water path, respectively. The instruments collected initial datasets during two snowstorm events and two snow shower events in March 2017. The radar scan strategy was a combination of PPI scans at 4 elevation angles (10, 20, 45, and 60°) and RHI scans in polarimetry mode, and zenith pointing with Doppler spectra collection. During the snowstorm events the radar observed relatively larger ZDR (1-1.5 dB) and enhanced KDP (1-2 ° km-1) at heights corresponding to a plate/dendrite crystal growth regime. The Doppler spectra showed that slower-falling particles ( 1 m s-1). The weakly increased ZDR could be produced by large, faster falling particles such as quasi-spherical aggregates, while the enhanced KDP could be produced by highly-oriented oblate, slowly-falling particles. Below 2 km altitude, measurements of dual wavelength ratio (DWR) based on Ka and S-band reflectivities from the KASPR and NEXRAD radars were available. Larger DWR (>10 dB) suggested

  13. Quantitative measurement of blood flow dynamics in chorioallantoic membrane of chicken embryo using laser Doppler anemometry

    Science.gov (United States)

    Borozdova, M. A.; Stiukhina, E. S.; Sdobnov, A. A.; Fedosov, I. V.; Postnov, D. E.; Tuchin, V. V.

    2016-04-01

    We report the results on in ovo application of developed Laser Doppler Anemometer (LDA) device. The chorioallantoic membrane (CAM) of 9-13 days chicken embryos was used as a biological model that allows an easy access to both arterial and venous vessels of different size. The key point of our study was to find out how the periodic and aperiodic pulsations of blood flow (which are inevitable in living organism) will affect the LDA functions and measuring capability. Specifically, we (i) developed the technique to extract and refine the pulse rhythm from the signal received from a vessel, and (ii) analyzed the changes in power spectra of LDA signal that are caused by heart beating and considerably complicate the reliable measurement of Doppler shift. Our main conclusion is that the algorithm of LDA data processing need to be improved, and this possibly can be done by counting the information on current phase of cardiac cycle.

  14. Measurement of two-dimensional Doppler wind fields using a field widened Michelson interferometer.

    Science.gov (United States)

    Langille, Jeffery A; Ward, William E; Scott, Alan; Arsenault, Dennis L

    2013-03-10

    An implementation of the field widened Michelson concept has been applied to obtain high resolution two-dimensional (2D) images of low velocity (interferometer scanning mirror position is controlled to subangstrom precision with subnanometer repeatability using the multi-application low-voltage piezoelectric instrument control electronics developed by COM DEV Ltd.; it is the first implementation of this system as a phase stepping Michelson. In this paper the calibration and characterization of the Doppler imaging system is described and the planned implementation of this new technique for imaging 2D wind and irradiance fields using the earth's airglow is introduced. Observations of Doppler winds produced by a rotating wheel are reported and shown to be of sufficient precision for buoyancy wave observations in airglow in the mesopause region of the terrestrial atmosphere.

  15. The effectiveness of Doppler controlled hemorrhoidal artery ligation ...

    African Journals Online (AJOL)

    In this work, we discuss the preliminary results of the effectiveness of the hemorrhoidal artery ligation under control Doppler as a new technique for the treatment of hemorrhoids. We report the results of patients with hemorrhoids we have followed over a period of one year who were treated with HAL Doppler. The intra-and ...

  16. Musculoskeletal colour/power Doppler in sports medicine

    DEFF Research Database (Denmark)

    Boesen, M I; Boesen, M; Langberg, Henning

    2010-01-01

    This review article discusses the aspects of sports medicine where musculoskeletal Doppler ultrasound has valuable contribution in diagnosis and/or treatment of some of the typical musculoskeletal sports injuries. Also, conditions where the Doppler ultrasound has no value are discussed. Some...

  17. 21 CFR 892.1550 - Ultrasonic pulsed doppler imaging system.

    Science.gov (United States)

    2010-04-01

    ... system. (a) Identification. An ultrasonic pulsed doppler imaging system is a device that combines the... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ultrasonic pulsed doppler imaging system. 892.1550... include signal analysis and display equipment, patient and equipment supports, component parts, and...

  18. Micro-Doppler classification of riders and riderless horses

    Science.gov (United States)

    Tahmoush, David

    2014-05-01

    Micro-range Micro-Doppler can be used to isolate particular parts of the radar signature, and in this case we demonstrate the differences in the signature between a walking horse versus a walking horse with a rider. Using micro-range micro-Doppler, we can distinguish the radar returns from the rider as separate from the radar returns of the horse.

  19. Correlation between Spectral Index and Doppler Factor for a ...

    Indian Academy of Sciences (India)

    Abstract. Relativistic beaming effect is important for blazars. In a very recent work, γ-ray Doppler factors were calculated for a sample of Fermi blazars (Fan et al. 2013). In this work, we investigated the correlation between the Doppler factor and the effective spectral index, αOX, and found an anticorrelation between them.

  20. Compressive sensing for high resolution profiles with enhanced Doppler performance

    NARCIS (Netherlands)

    Anitori, L.; Hoogeboom, P.; Chevalier, F. Le; Otten, M.P.G.

    2012-01-01

    In this paper we demonstrate how Compressive Sensing (CS) can be used in pulse-Doppler radars to improve the Doppler performance while preserving range resolution. We investigate here two types of stepped frequency waveforms, the coherent frequency bursts and successive frequency ramps, which can be