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Sample records for twisted pc double

  1. Twist limits for late twisting double somersaults on trampoline.

    Science.gov (United States)

    Yeadon, M R; Hiley, M J

    2017-06-14

    An angle-driven computer simulation model of aerial movement was used to determine the maximum amount of twist that could be produced in the second somersault of a double somersault on trampoline using asymmetrical movements of the arms and hips. Lower bounds were placed on the durations of arm and hip angle changes based on performances of a world trampoline champion whose inertia parameters were used in the simulations. The limiting movements were identified as the largest possible odd number of half twists for forward somersaulting takeoffs and even number of half twists for backward takeoffs. Simulations of these two limiting movements were found using simulated annealing optimisation to produce the required amounts of somersault, tilt and twist at landing after a flight time of 2.0s. Additional optimisations were then run to seek solutions with the arms less adducted during the twisting phase. It was found that 3½ twists could be produced in the second somersault of a forward piked double somersault with arms abducted 8° from full adduction during the twisting phase and that three twists could be produced in the second somersault of a backward straight double somersault with arms fully adducted to the body. These two movements are at the limits of performance for elite trampolinists. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Twisted quantum doubles

    Directory of Open Access Journals (Sweden)

    Daijiro Fukuda

    2004-01-01

    Full Text Available Using diagrammatic pictures of tensor contractions, we consider a Hopf algebra (Aop⊗ℛλA** twisted by an element ℛλ∈A*⊗Aop corresponding to a Hopf algebra morphism λ:A→A. We show that this Hopf algebra is quasitriangular with the universal R-matrix coming from ℛλ when λ2=idA, generalizing the quantum double construction which corresponds to the case λ=idA.

  3. The geometrical origin of the strain-twist coupling in double helices

    Directory of Open Access Journals (Sweden)

    Kasper Olsen

    2011-03-01

    Full Text Available A simple geometrical explanation for the counterintuitive phenomenon when twist leads to extension in double helices is presented. The coupling between strain and twist is investigated using a tubular description. It is shown that the relation between strain and rotation is universal and depends only on the pitch angle. For pitch angles below 39.4° strain leads to further winding, while for larger pitch angles strain leads to unwinding. The zero-twist structure, with a pitch angle of 39.4°, is at the unique point between winding and unwinding and independent of the mechanical properties of the double helix. The existence of zero-twist structures, i.e. structures that display neither winding, nor unwinding under strain is discussed. Close-packed double helices are shown to extend rather than shorten when twisted. Numerical estimates of this elongation upon winding are given for DNA, chromatin, and RNA.

  4. Comparison of split double and triple twists in pair figure skating.

    Science.gov (United States)

    King, Deborah L; Smith, Sarah L; Brown, Michele R; McCrory, Jean L; Munkasy, Barry A; Scheirman, Gary I

    2008-05-01

    In this study, we compared the kinematic variables of the split triple twist with those of the split double twist to help coaches and scientists understand these landmark pair skating skills. High-speed video was taken during the pair short and free programmes at the 2002 Salt Lake City Winter Olympics and the 2003 International Skating Union Grand Prix Finals. Three-dimensional analyses of 14 split double twists and 15 split triple twists from eleven pairs were completed. In spite of considerable variability in the performance variables among the pairs, the main difference between the split double twists and split triple twists was an increase in rotational rate. While eight of the eleven pairs relied primarily on an increased rotational rate to complete the split triple twist, three pairs employed a combined strategy of increased rotational rate and increased flight time due predominantly to delayed or lower catches. These results were similar to observations of jumps in singles skating for which the extra rotation is typically due to an increase in rotational velocity; increases in flight time come primarily from delayed landings as opposed to additional height during flight. Combining an increase in flight time and rotational rate may be a good strategy for completing the split triple twist in pair skating.

  5. Supersymmetric gauged double field theory: systematic derivation by virtue of twist

    International Nuclear Information System (INIS)

    Cho, Wonyoung; Fernández-Melgarejo, J.J.; Jeon, Imtak; Park, Jeong-Hyuck

    2015-01-01

    In a completely systematic and geometric way, we derive maximal and half-maximal supersymmetric gauged double field theories in lower than ten dimensions. To this end, we apply a simple twisting ansatz to the D=10 ungauged maximal and half-maximal supersymmetric double field theories constructed previously within the so-called semi-covariant formalism. The twisting ansatz may not satisfy the section condition. Nonetheless, all the features of the semi-covariant formalism, including its complete covariantizability, are still valid after the twist under alternative consistency conditions. The twist allows gaugings as supersymmetry preserving deformations of the D=10 untwisted theories after Scherk-Schwarz-type dimensional reductions. The maximal supersymmetric twist requires an extra condition to ensure both the Ramond-Ramond gauge symmetry and the 32 supersymmetries unbroken.

  6. The geometrical origin of the strain-twist coupling in double helices

    DEFF Research Database (Denmark)

    Olsen, Kasper; Bohr, Jakob

    2011-01-01

    A simple geometrical explanation for the counterintuitive phenomenon when twist leads to extension in double helices is presented. The coupling between strain and twist is investigated using a tubular description. It is shown that the relation between strain and rotation is universal and depends...

  7. TiO2/water Nanofluid Heat Transfer in Heat Exchanger Equipped with Double Twisted-Tape Inserts

    Science.gov (United States)

    Eiamsa-ard, S.; Ketrain, R.; Chuwattanakul, V.

    2018-05-01

    Nowadays, heat transfer enhancement plays an important role in improving efficiency of heat transfer and thermal systems for numerous areas such as heat recovery processes, chemical reactors, air-conditioning/refrigeration system, food engineering, solar air/water heater, cooling of high power electronics etc. The present work presents the experimental results of the heat transfer enhancement of TiO2/water nanofluid in a heat exchanger tube fitted with double twisted tapes. The study covered twist ratios of twisted tapes (y/w) of 1.5, 2.0, and 2.5) while the concentration of the nanofluid was kept constant at 0.05% by volume. Observations show that heat transfer, friction loss and thermal performance increase as twist ratio (y/w) decreases. The use of the nanofluid in the tube equipped with the double twisted-tapes with the smallest twist ratio (y/w = 1.5) results in the increases of heat transfer rates and friction factor up to 224.8% and 8.98 times, respectively as compared to those of water. In addition, the experimental results performed that double twisted tapes induced dual swirling-flows which played an important role in improving fluid mixing and heat transfer enhancement. It is also observed that the TiO2/water nanofluid was responsible for low pressure loss behaviors.

  8. Numerical Analysis of Heat transfer Enhancement in a double pipe heat exchanger with a holed twisted tape

    Directory of Open Access Journals (Sweden)

    Kumar Akarsh

    2018-01-01

    Full Text Available In the present study numerical analysis of enhancement in heat transfer characteristics in a double pipe heat exchanger is studied using a holed twisted tape.The twisted tape with a constant twist ratio is inserted in a double pipe heat exchanger. Holes of diameter 1mm, 3 mm and 5 mm were drilled at regular pitch throughout the length of the tape. Numerical modeling of a double pipe heat exchanger with the holed twisted tape was constructed considering hot fluid flowing in the inner pipe and cold fluid through the annulus.Simulation was done for varied mass flow rates of hot fluid in the turbulent condition keeping the mass flow rate of cold fluid being constant. Thermal properties like Outlet temperatures, Nusselt number, overall heat transfer coefficient, heat transfer rate and pressure drop were determined for all the cases. Results indicated that normaltwisted tape without holes performed better than the bare tube. In the tested range of mass flow rates the average Nusselt number and heat transfer rate were increased by 85% and 34% respectively. Performance of Twisted tape with holes was slightly reduced than the normal twisted tape and it deteriorated further for higher values hole diameter. Pressure drop was found to be higher for the holed twisted tape than the normal tape.

  9. Double scaling limits and twisted non-critical superstrings

    International Nuclear Information System (INIS)

    Bertoldi, Gaetano

    2006-01-01

    We consider double-scaling limits of multicut solutions of certain one matrix models that are related to Calabi-Yau singularities of type A and the respective topological B model via the Dijkgraaf-Vafa correspondence. These double-scaling limits naturally lead to a bosonic string with c ≤ 1. We argue that this non-critical string is given by the topologically twisted non-critical superstring background which provides the dual description of the double-scaled little string theory at the Calabi-Yau singularity. The algorithms developed recently to solve a generic multicut matrix model by means of the loop equations allow to show that the scaling of the higher genus terms in the matrix model free energy matches the expected behaviour in the topological B-model. This result applies to a generic matrix model singularity and the relative double-scaling limit. We use these techniques to explicitly evaluate the free energy at genus one and genus two

  10. Twisting products in Hopf algebras and the construction of the quantum double

    International Nuclear Information System (INIS)

    Ferrer Santos, W.R.

    1992-04-01

    Let H be a finite dimensional Hopf algebra and B an (H, H*)-comodule algebra. The purpose of this note is to present a construction in which the product of B is twisted by the given actions. The constructions of the smash product and of the Quantum Double appear as special cases. (author). 7 refs

  11. [Effects of slow twisting needle insertion and tubing needle insertion at Neiguan (PC 6) on cardiovascular function: a comparative study].

    Science.gov (United States)

    Ning, Shaoli; Zhao, Lihua; Xu, Lingjun; Huang, Yu; Pang, Yong; Huang, Dingjian

    2016-01-01

    To compare the effects between slow twisting needle insertion and tubing needle insertion. With cross-over design, 100 healthy young subjects (half male and half female) aged from 19 to 23 years were randomly divided into two groups by random digital table, 50 cases in each one. At the first stage, subjects in the group A were treated with slow twisting needle insertion while, subjects in,the group B were treated with tubing needle insertion. One week later, the procedure of second stage was performed alternately. The needle was inserted into Neiguan (PC 6) with two methods by one acupuncturist. The needle was retained for 5 min before removal. Five min before needle insertion as well as needle withdrawal and 30 min after needle withdrawal, ZXG-E automatic cardiovascular diagnostic apparatus was used to test cardiovascular function. At the tim of needle withdrawal, slow twisting needle insertion could improve effect work of kinetics (EWK), effective blood volume (BV) and reduce elastic expansion coefficient of blood vessel (FEK) and left ventricular spray blood impedance (VER), which was significantly different from tubing needle insertion (all P 0.05). The slow twisting needle insertion is significantly superior to tubing needle insertion on lowering vascular tension and VER, improving EWK and BV.

  12. Enhancement of pump absorption efficiency by bending and twisting of double clad rare earth doped fibers (Conference Presentation)

    Science.gov (United States)

    Koška, Pavel; Peterka, Pavel; Doya, Valérie; Aubrecht, Jan; Kasik, Ivan; Podrazký, Ondřej

    2017-05-01

    High-power operation of fiber lasers was enabled by the invention of cladding-pumping in a double-clad fiber structure. Because of existence of so called skew rays in the inner clad of the fiber, pump absorption saturates along the fiber and pumping becomes inefficient. First studies of pump absorption efficiency enhancement were focused on fibers with broken circular symmetry of inner cladding eliminating skew rays [1,2]. Later, techniques of unconventional fiber coiling were proposed [3]. However, theoretical studies were limited to the assumption of a straight fiber. Even recently, the rigorous model accounting for fiber bending and twisting was described [4-6]. It was found that bending of the fiber influences modal spectra of the pump radiation and twisting provides quite efficient mode-scrambling. These effects in a synergic manner significantly enhances pump absorption rate in double clad fibers and improves laser system efficiency. In our contribution we review results of numerical modelling of pump absorption in various types of double-clad fibers, e.g., with cross section shape of hexagon, stadium, and circle; two-fiber bundle (so-called GTWave fiber structure) a panda fibers are also analyzed. We investigate pump field modal spectra evolution in hexagonally shaped fiber in straight, bended, and simultaneously bended and twisted fiber which brings new quality to understanding of the mode-scrambling and pump absorption enhancement. Finally, we evaluate the impact of enhanced pump absorption on signal gain in the fiber. These results can have practical impact in construction of fiber lasers: with pump absorption efficiency optimized by our new model (the other models did not take into account fiber twist), the double-clad fiber of shorter length can be used in the fiber lasers and amplifiers. In such a way the harmful influence of background losses and nonlinear effects can be minimized. [1] Doya, V., Legrand, O., Mortessagne, F., "Optimized absorption in a

  13. Flux compactifications, twisted tori and doubled geometry

    International Nuclear Information System (INIS)

    Reid-Edwards, R.A.

    2009-01-01

    In [1] an O(D,D)-covariant sigma model describing the embedding of a closed world-sheet into the 2D-dimensional twisted torus X was proposed. Such sigma models provide a universal description of string theory with target spaces related by the action of T-duality. In this article a six-dimensional toy example is studied in detail. Different polarisations of the six-dimensional target space give different three-dimensional string backgrounds including a nilmanifold with H-flux, a T-fold with R-flux and a new class of T-folds. Global issues and connections with the doubled torus formalism are discussed. Finally, the sigma model introduced in [1], describing the embedding of a world-sheet into X, is generalised to one describing a target space which is a bundle of X over a base M d , allowing for a more complete description of the associated gauged supergravity from the world-sheet perspective to be given.

  14. Effect of Twisted-Tape Turbulators and Nanofluid on Heat Transfer in a Double Pipe Heat Exchanger

    Directory of Open Access Journals (Sweden)

    Heydar Maddah

    2014-01-01

    Full Text Available Heat transfer and overall heat transfer in a double pipe heat exchanger fitted with twisted-tape elements and titanium dioxide nanofluid were studied experimentally. The inner and outer diameters of the inner tube were 8 and 16 mm, respectively, and cold and hot water were used as working fluids in shell side and tube side. The twisted tapes were made from aluminum sheet with tape thickness (d of 1 mm, width (W of 5 mm, and length of 120 cm. Titanium dioxide nanoparticles with a diameter of 30 nm and a volume concentration of 0.01% (v/v were prepared. The effects of temperature, mass flow rate, and concentration of nanoparticles on the overall heat transfer coefficient, heat transfer changes in the turbulent flow regime Re≥2300, and counter current flow were investigated. When using twisted tape and nanofluid, heat transfer coefficient was about 10 to 25 percent higher than when they were not used. It was also observed that the heat transfer coefficient increases with operating temperature and mass flow rate. The experimental results also showed that 0.01% TiO2/water nanofluid with twisted tape has slightly higher friction factor and pressure drop when compared to 0.01% TiO2/water nanofluid without twisted tape. The empirical correlations proposed for friction factor are in good agreement with the experimental data.

  15. Twisted speckle entities inside wave-front reversal mirrors

    International Nuclear Information System (INIS)

    Okulov, A. Yu

    2009-01-01

    The previously unknown property of the optical speckle pattern reported. The interference of a speckle with the counterpropagating phase-conjugated (PC) speckle wave produces a randomly distributed ensemble of a twisted entities (ropes) surrounding optical vortex lines. These entities appear in a wide range of a randomly chosen speckle parameters inside the phase-conjugating mirrors regardless to an internal physical mechanism of the wave-front reversal. These numerically generated interference patterns are relevant to the Brillouin PC mirrors and to a four-wave mixing PC mirrors based upon laser trapped ultracold atomic cloud.

  16. Twisted quantum double model of topological order with boundaries

    Science.gov (United States)

    Bullivant, Alex; Hu, Yuting; Wan, Yidun

    2017-10-01

    We generalize the twisted quantum double model of topological orders in two dimensions to the case with boundaries by systematically constructing the boundary Hamiltonians. Given the bulk Hamiltonian defined by a gauge group G and a 3-cocycle in the third cohomology group of G over U (1 ) , a boundary Hamiltonian can be defined by a subgroup K of G and a 2-cochain in the second cochain group of K over U (1 ) . The consistency between the bulk and boundary Hamiltonians is dictated by what we call the Frobenius condition that constrains the 2-cochain given the 3-cocyle. We offer a closed-form formula computing the ground-state degeneracy of the model on a cylinder in terms of the input data only, which can be naturally generalized to surfaces with more boundaries. We also explicitly write down the ground-state wave function of the model on a disk also in terms of the input data only.

  17. Electrochemistry and spectroelectrochemistry of tert-butylcalix[4]arene bridged bis double-decker lutetium(III) phthalocyanine, Lu2Pc4 and dimeric lutetium(III) phthalocyanine, Lu2Pc2(OAc)2

    International Nuclear Information System (INIS)

    Koca, Atif; Ceyhan, Tanju; Erbil, Mehmet K.; Ozkaya, Ali Riza; Bekaroglu, Ozer

    2007-01-01

    In this study, electrochemical, electrochromic and spectroelectrochemical properties of a tert-butylcalix[4]arene bridged bis double-decker lutetium(III) phthalocyanine (Lu 2 Pc 4 2) were investigated explicitly as compared with a tert-butylcalix[4]arene bridged dimeric lutetium(III) phthalocyanine [Lu 2 Pc 2 (OAc) 2 1]. Distinctive differences between electrochemical and electrochromic properties of 1 and 2 were detected. Moreover, the properties of 1 and 2 were compared with previously reported S 4 (CH 2 ) 4 bridged Lu 2 Pc 2 (OAc) 2 and Lu 2 Pc 4 . The calixarene bridged phthalocyanine (Pc) compounds, 1 and 2 showed well-defined electrochromic behaviour with green-blue and blue-purple colour transitions. The enhanced electrochromic properties of 2, as compared to 1, were attributed to its double-decker structure, probably allowing the formation of suitable ion channels for the counter ion movement in the solid film

  18. Effect of Twisting and Stretching on Magneto Resistance and Spin Filtration in CNTs

    Directory of Open Access Journals (Sweden)

    Anil Kumar Singh

    2017-08-01

    Full Text Available Spin-dependent quantum transport properties in twisted carbon nanotube and stretched carbon nanotube are calculated using density functional theory (DFT and non-equilibrium green’s function (NEGF formulation. Twisting and stretching have no effect on spin transport in CNTs at low bias voltages. However, at high bias voltages the effects are significant. Stretching restricts any spin-up current in antiparallel configuration (APC, which results in higher magneto resistance (MR. Twisting allows spin-up current almost equivalent to the pristine CNT case, resulting in lower MR. High spin filtration is observed in PC and APC for pristine, stretched and twisted structures at all applied voltages. In APC, at low voltages spin filtration in stretched CNT is higher than in pristine and twisted ones, with pristine giving a higher spin filtration than twisted CNT.

  19. Four-point functions with a twist

    Energy Technology Data Exchange (ETDEWEB)

    Bargheer, Till [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany). Theory Group

    2017-01-15

    We study the OPE of correlation functions of local operators in planar N=4 super Yang-Mills theory. The considered operators have an explicit spacetime dependence that is defined by twisting the translation generators with certain R-symmetry generators. We restrict to operators that carry a small number of excitations above the twisted BMN vacuum. The OPE limit of the four-point correlator is dominated by internal states with few magnons on top of the vacuum. The twisting directly couples all spacetime dependence of the correlator to these magnons. We analyze the OPE in detail, and single out the extremal states that have to cancel all double-trace contributions.

  20. miR-1271 inhibits migration, invasion and epithelial-mesenchymal transition by targeting ZEB1 and TWIST1 in pancreatic cancer cells

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Huaize [Department of Developmental Genetics, Nanjing Medical University, Nanjing 210029 (China); Wang, Han [The First Clinical Medical College of Nanjing Medical University, Nanjing 210029 (China); Liu, Xiaoxiao [Department of Biotechnology, Nanjing Medical University, Nanjing 210029 (China); Yu, Tingting, E-mail: tingting@njmu.edu.cn [Department of Developmental Genetics, Nanjing Medical University, Nanjing 210029 (China)

    2016-04-01

    Pancreatic cancer (PC) remains one of the most lethal types of cancer in adults. The purpose of this study was to determine the role of miR-1271 in regulation of epithelial mesenchymal transition (EMT) and metastasis of pancreatic cancer cells. miR-1271 was identified to be significantly down-regulated in PC tissues by miRNA array. Also, an increase of EMT-regulators ZEB1 and TWIST1 expression level is accompanied by a decrease of miR-1271. We showed that expression of miR-1271 was significantly down-regulated in PC tissues as compared with that in normal tissues. In addition, our results showed that miR-1271 expression levels were decreased while ZEB1 and TWIST1 expression levels were increased in detected PC cell lines. Moreover, ectopic expression of miR-1271 suppressed and antagomiR-1271 promoted proliferation, migration, and invasion in SW1990 and PANC-1 cells. Bioinformatics coupled with luciferase and Western blot assays also revealed that miR-1271 inhibited expression of ZEB1 and TWIST1, which are master regulators of tumor metastasis. Our study first indicates that miR-1271 functions as a suppressor in regulating of pancreatic cancer EMT by targeting ZEB1 and TWIST1, and it promise as a therapeutic target and prognostic marker for metastatic pancreatic cancer. - Highlights: • miR-1271 is downregulated in pancreatic cancer tissues and cell lines. • miR-1271 regulates cell metastasis ability and EMT marker expression. . • miR-1271 directly targets ZEB1 and TWIST1. • ZEB1 and TWIST1 are functionally related to the effects of miR-1271.

  1. miR-1271 inhibits migration, invasion and epithelial-mesenchymal transition by targeting ZEB1 and TWIST1 in pancreatic cancer cells

    International Nuclear Information System (INIS)

    Liu, Huaize; Wang, Han; Liu, Xiaoxiao; Yu, Tingting

    2016-01-01

    Pancreatic cancer (PC) remains one of the most lethal types of cancer in adults. The purpose of this study was to determine the role of miR-1271 in regulation of epithelial mesenchymal transition (EMT) and metastasis of pancreatic cancer cells. miR-1271 was identified to be significantly down-regulated in PC tissues by miRNA array. Also, an increase of EMT-regulators ZEB1 and TWIST1 expression level is accompanied by a decrease of miR-1271. We showed that expression of miR-1271 was significantly down-regulated in PC tissues as compared with that in normal tissues. In addition, our results showed that miR-1271 expression levels were decreased while ZEB1 and TWIST1 expression levels were increased in detected PC cell lines. Moreover, ectopic expression of miR-1271 suppressed and antagomiR-1271 promoted proliferation, migration, and invasion in SW1990 and PANC-1 cells. Bioinformatics coupled with luciferase and Western blot assays also revealed that miR-1271 inhibited expression of ZEB1 and TWIST1, which are master regulators of tumor metastasis. Our study first indicates that miR-1271 functions as a suppressor in regulating of pancreatic cancer EMT by targeting ZEB1 and TWIST1, and it promise as a therapeutic target and prognostic marker for metastatic pancreatic cancer. - Highlights: • miR-1271 is downregulated in pancreatic cancer tissues and cell lines. • miR-1271 regulates cell metastasis ability and EMT marker expression. . • miR-1271 directly targets ZEB1 and TWIST1. • ZEB1 and TWIST1 are functionally related to the effects of miR-1271.

  2. Electrochemistry and spectroelectrochemistry of tert-butylcalix[4]arene bridged bis double-decker lutetium(III) phthalocyanine, Lu{sub 2}Pc{sub 4} and dimeric lutetium(III) phthalocyanine, Lu{sub 2}Pc{sub 2}(OAc){sub 2}

    Energy Technology Data Exchange (ETDEWEB)

    Koca, Atif [Chemical Engineering Department, Engineering Faculty, Marmara University, TR34722 Goeztepe, Istanbul (Turkey); Ceyhan, Tanju; Erbil, Mehmet K. [Department of Biochemistry, Division of Organic Chemistry, Guelhane Medical Academy (GATA), Ankara (Turkey); Ozkaya, Ali Riza [Department of Chemistry, Marmara University, TR34722 Goeztepe, Istanbul (Turkey)], E-mail: aliozkaya@marmara.edu.tr; Bekaroglu, Ozer [Department of Chemistry, Technical University of Istanbul, TR34469 Maslak, Istanbul (Turkey)], E-mail: obek@itu.edu.tr

    2007-11-09

    In this study, electrochemical, electrochromic and spectroelectrochemical properties of a tert-butylcalix[4]arene bridged bis double-decker lutetium(III) phthalocyanine (Lu{sub 2}Pc{sub 4}2) were investigated explicitly as compared with a tert-butylcalix[4]arene bridged dimeric lutetium(III) phthalocyanine [Lu{sub 2}Pc{sub 2}(OAc){sub 2}1]. Distinctive differences between electrochemical and electrochromic properties of 1 and 2 were detected. Moreover, the properties of 1 and 2 were compared with previously reported S{sub 4}(CH{sub 2}){sub 4} bridged Lu{sub 2}Pc{sub 2}(OAc){sub 2} and Lu{sub 2}Pc{sub 4}. The calixarene bridged phthalocyanine (Pc) compounds, 1 and 2 showed well-defined electrochromic behaviour with green-blue and blue-purple colour transitions. The enhanced electrochromic properties of 2, as compared to 1, were attributed to its double-decker structure, probably allowing the formation of suitable ion channels for the counter ion movement in the solid film.

  3. Twisting short dsDNA with applied tension

    Science.gov (United States)

    Zoli, Marco

    2018-02-01

    The twisting deformation of mechanically stretched DNA molecules is studied by a coarse grained Hamiltonian model incorporating the fundamental interactions that stabilize the double helix and accounting for the radial and angular base pair fluctuations. The latter are all the more important at short length scales in which DNA fragments maintain an intrinsic flexibility. The presented computational method simulates a broad ensemble of possible molecule conformations characterized by a specific average twist and determines the energetically most convenient helical twist by free energy minimization. As this is done for any external load, the method yields the characteristic twist-stretch profile of the molecule and also computes the changes in the macroscopic helix parameters i.e. average diameter and rise distance. It is predicted that short molecules under stretching should first over-twist and then untwist by increasing the external load. Moreover, applying a constant load and simulating a torsional strain which over-twists the helix, it is found that the average helix diameter shrinks while the molecule elongates, in agreement with the experimental trend observed in kilo-base long sequences. The quantitative relation between percent relative elongation and superhelical density at fixed load is derived. The proposed theoretical model and computational method offer a general approach to characterize specific DNA fragments and predict their macroscopic elastic response as a function of the effective potential parameters of the mesoscopic Hamiltonian.

  4. Electronic and Optical Properties of Twisted Bilayer Graphene

    Science.gov (United States)

    Huang, Shengqiang

    symmetry is broken with an external electric field. We observe a double-line profile of these states on the domain walls, only occurring when the AB and BA regions are gaped. These states give rise to channels that could transport charge in a dissipationless manner making twisted bilayer graphene a promising platform to realize controllable topological networks for future applications.

  5. Twisted supersymmetry: Twisted symmetry versus renormalizability

    International Nuclear Information System (INIS)

    Dimitrijevic, Marija; Nikolic, Biljana; Radovanovic, Voja

    2011-01-01

    We discuss a deformation of superspace based on a Hermitian twist. The twist implies a *-product that is noncommutative, Hermitian and finite when expanded in a power series of the deformation parameter. The Leibniz rule for the twisted supersymmetry transformations is deformed. A minimal deformation of the Wess-Zumino action is proposed and its renormalizability properties are discussed. There is no tadpole contribution, but the two-point function diverges. We speculate that the deformed Leibniz rule, or more generally the twisted symmetry, interferes with renormalizability properties of the model. We discuss different possibilities to render a renormalizable model.

  6. Optical yarn assessment system for twist measurement in rotor-spun yarn

    International Nuclear Information System (INIS)

    Jhatial, R.A.

    2015-01-01

    This paper presents the development of an optical yarn assessment system for evaluation of twist and structure of twisted yarn. The system comprises a yarn carriage unit, a video microscope and a personal computer. This system was used in conjunction with the well-known tracer fibre technique. This system enables digital images to be grabbed and continuous movies of the yarn to be recorded in order to facilitate the measurement of twist and the analysis of yarn structure. Yarn samples from polyester, viscose and cotton with 35 tex and 485 turns/meter were spun from the roving with 2.3% of black fibres on the SKF laboratory ring frame. In order to measure the twist in the rotor yarns with the optical yarn assessment system, a set of yarn samples from same fibres were spun on RU 14 rotor machine with 35 tex and 475 turns/meter. The twist was measured with the optical yarn assessment system and sixty tests of each sample were carried out on the Zweigle D301. It is clear from the results that there is consistency in the twist of ring-spun yarn measured by the optical yarn assessment system. However, the measured twist with the Zwiegle D301 is inconsistent in the different yarns. The difference in the mean twist measured with the optical twist measuring system and the double untwist-twist method was not significant at a 5% probability level when data was analyzed with t test by using SPSS (Statistical Package for Social Sciences). (author)

  7. Twisted light

    CSIR Research Space (South Africa)

    Forbes, A

    2010-12-01

    Full Text Available Research at the Mathematical Optics Group uses "twisted" light to study new quatum-based information security systems. In order to understand the structure of "twisted" light, it is useful to start with an ordinary light beam with zero twist, namely...

  8. PC-BLAS, PC Linear Algebra Subroutines

    International Nuclear Information System (INIS)

    Hanson, R.J.

    1989-01-01

    1 - Description of program or function: PC-BLAS is a highly optimized version of the Basic Linear Algebra Subprograms (BLAS), a standardized set of 38 routines that perform low-level operations on vectors of numbers in single- and double-precision real and complex arithmetic. Routines are included to find the index of the largest component of a vector, apply a Givens or modified Givens rotation, multiply a vector by a constant, determine the Euclidean length, perform a dot product, swap and copy vectors, and find the norm of a vector. 2 - Restrictions on the complexity of the problem: The number of components in any vector and the spacing or stride between their entries must not exceed 32,767 (2 15 -1). PC-BLAS will not work with an 80286 CPU operating in 'protected' mode

  9. Twist-3 effect from the longitudinally polarized proton for ALT in hadron production from pp collisions

    Directory of Open Access Journals (Sweden)

    Yuji Koike

    2016-08-01

    Full Text Available We compute the contribution from the longitudinally polarized proton to the twist-3 double-spin asymmetry ALT in inclusive (light hadron production from proton–proton collisions, i.e., p↑p→→hX. We show that using the relevant QCD equation-of-motion relation and Lorentz invariance relation allows one to eliminate the twist-3 quark-gluon correlator (associated with the longitudinally polarized proton in favor of one-variable twist-3 quark distributions and the (twist-2 transversity parton density. Including this result with the twist-3 pieces associated with the transversely polarized proton and unpolarized final-state hadron (which have already been calculated in the literature, we now have the complete leading-order cross section for this process.

  10. Massive deformations of Type IIA theory within double field theory

    Science.gov (United States)

    Çatal-Özer, Aybike

    2018-02-01

    We obtain massive deformations of Type IIA supergravity theory through duality twisted reductions of Double Field Theory (DFT) of massless Type II strings. The mass deformation is induced through the reduction of the DFT of the RR sector. Such reductions are determined by a twist element belonging to Spin+(10, 10), which is the duality group of the DFT of the RR sector. We determine the form of the twists and give particular examples of twists matrices, for which a massive deformation of Type IIA theory can be obtained. In one of the cases, requirement of gauge invariance of the RR sector implies that the dilaton field must pick up a linear dependence on one of the dual coordinates. In another case, the choice of the twist matrix violates the weak and the strong constraints explicitly in the internal doubled space.

  11. Twisting dependent properties of twisted carbon nanotube fibers: microstructure and strain transfer factors

    International Nuclear Information System (INIS)

    Zhou, Jinyuan; Xie, Erqing; Sun, Gengzhi; Zhan, Zhaoyao; Zheng, Lianxi

    2014-01-01

    The dependences of twisting parameters on the electric and mechanical properties of twisted CNT fibers were systematically studied. Results from electric and mechanical measurements showed that twisting intensity is very effective to improve the electric and mechanical properties of CNT fibers. Further calculations combined with Raman results indicate that the twisting treatments, to a certain extent, can greatly enhance the strain transfer factors of the samples, which dominates the mechanical properties of CNT fibers. In addition, studies on the effect of twisting speeds suggested that lower twisting speed can lead to higher uniformity but lower performances in the electric and mechanical properties, higher twisting speed to higher Young’s modulus and higher conductance but lower uniformities. Ultra-strong uniform CNT fibers need to be prepared with a suitable twisting speed. (paper)

  12. Factorization of differential expansion for antiparallel double-braid knots

    Science.gov (United States)

    Morozov, A.

    2016-09-01

    Continuing the quest for exclusive Racah matrices, which are needed for evaluation of colored arborescent-knot polynomials in Chern-Simons theory, we suggest to extract them from a new kind of a double-evolution — that of the antiparallel double-braids, which is a simple two-parametric family of two-bridge knots, generalizing the one-parametric family of twist knots. In the case of rectangular representations R = [ r s ] we found an evidence that the corresponding differential expansion miraculously factorizes and can be obtained from that for the twist knots. This reduces the problem of rectangular exclusive Racah to constructing the answers for just a few twist knots. We develop a recent conjecture on the structure of differential expansion for the simplest members of this family (the trefoil and the figure-eight knot) and provide the exhaustive answer for the first unknown case of R = [33]. The answer includes HOMFLY of arbitrary twist and double-braid knots and Racah matrices overline{S} and S — what allows to calculate [33]-colored polynomials for arbitrary arborescent (double-fat) knots. For generic rectangular representations fully described are only the contributions of the single-floor pyramids. One step still remains to be done.

  13. Wrinkles, loops, and topological defects in twisted ribbons

    Science.gov (United States)

    Chopin, Julien

    Nature abounds with elastic ribbon like shapes including double-stranded semiflexible polymers, graphene and metal oxide nanoribbons which are examples of elongated elastic structures with a strongly anisotropic cross-section. Due to this specific geometry, it is far from trivial to anticipate if a ribbon should be considered as a flat flexible filament or a narrow thin plate. We thus perform an experiment in which a thin elastic ribbon is loaded using a twisting and traction device coupled with a micro X-ray computed tomography machine allowing a full 3D shape reconstruction. A wealth of morphological behaviors can be observed including wrinkled helicoids, curled and looped configurations, and faceted ribbons. In this talk, I will show that most morphologies can be understood using a far-from-threshold approach and simple scaling arguments. Further, we find that the various shapes can be organized in a phase diagram using the twist, the tension, and the geometry of the ribbon as control parameters. Finally, I will discuss the spontaneous formation of topological defects with negatively-signed Gaussian charge at large twist and small but finite stretch.

  14. High-efficiency and multi-frequency polarization converters based on graphene metasurface with twisting double L-shaped unit structure array

    Science.gov (United States)

    Chen, Ming; Xiao, Xiaofei; Chang, Linzi; Wang, Congyun; Zhao, Deping

    2017-07-01

    In this work, a high-efficiency and tunable dual-frequency reflective polarization converter composed of graphene metasurface with twisting double L-shaped unit is firstly realized. Numerical results demonstrate that the device can convert a linearly polarized wave to its cross-polarized wave, and meantime it can also convert to a circularly polarized wave. Subsequently, one thickness of 500 nm SiO2 layer sandwiched by two graphene metasurfaces with similar pattern is stacked on the top of the two-layered structure, a four-frequency efficient reflective polarization converters is realized. Above all, those working frequencies can also be dynamically tuned within a large frequency range by adjusting the Fermi energy of the graphene, without reoptimizing and refabricating the nanostructures, which paves a novel way toward developing a controllable polarization converter for mid-infrared applications.

  15. DC conductivity of twisted bilayer graphene: Angle-dependent transport properties and effects of disorder

    Science.gov (United States)

    Andelković, M.; Covaci, L.; Peeters, F. M.

    2018-03-01

    The in-plane dc conductivity of twisted bilayer graphene is calculated using an expansion of the real-space Kubo-Bastin conductivity in terms of Chebyshev polynomials. We investigate within a tight-binding approach the transport properties as a function of rotation angle, applied perpendicular electric field, and vacancy disorder. We find that for high-angle twists, the two layers are effectively decoupled, and the minimum conductivity at the Dirac point corresponds to double the value observed in monolayer graphene. This remains valid even in the presence of vacancies, hinting that chiral symmetry is still preserved. On the contrary, for low twist angles, the conductivity at the Dirac point depends on the twist angle and is not protected in the presence of disorder. Furthermore, for low angles and in the presence of an applied electric field, we find that the chiral boundary states emerging between AB and BA regions contribute to the dc conductivity, despite the appearance of localized states in the AA regions. The results agree qualitatively with recent transport experiments in low-angle twisted bilayer graphene.

  16. Pump absorption in coiled and twisted double-clad hexagonal fiber: effect of launching conditions and core location

    Science.gov (United States)

    Dalidet, Romain; Peterka, Pavel; Doya, Valérie; Aubrecht, Jan; Koška, Pavel

    2018-02-01

    Ever extending applications of fiber lasers require energy efficient, high-power, small footprint and reliable fiber lasers and laser wavelength versatility. To meet these demands, next generation of active fibers for high-power fiber lasers is coming out that will eventually offer tailored spectroscopic properties, high robustness and reduced cooling requirements and improved efficiency through tailored pump absorption. We report on numerical modelling of the efficiency of the pump absorption in double clad active fibers with hexagonal shape of the inner cladding cross section and rare-earth-doped core. We analyze both the effect of different radii of the spool on which the fiber is coiled and different fiber twisting rates. Two different launching conditions were investigated: the Gaussian input pump beam and a speckle pattern that mimics the output of the pump laser diode pigtail. We have found that by asymmetric position of the rare-earth-doped core we can significantly improve the pump absorption.

  17. Twisted network programming essentials

    CERN Document Server

    Fettig, Abe

    2005-01-01

    Twisted Network Programming Essentials from O'Reilly is a task-oriented look at this new open source, Python-based technology. The book begins with recommendations for various plug-ins and add-ons to enhance the basic package as installed. It then details Twisted's collection simple network protocols, and helper utilities. The book also includes projects that let you try out the Twisted framework for yourself. For example, you'll find examples of using Twisted to build web services applications using the REST architecture, using XML-RPC, and using SOAP. Written for developers who want to s

  18. Effects of dielectric inhomogeneity on electrostatic twist rigidity of a helical biomolecule in Debye-Hückel regime

    Science.gov (United States)

    Rezaie-Dereshgi, Amir; Mohammad-Rafiee, Farshid

    2018-04-01

    The electrostatic interactions play a crucial role in biological systems. Here we consider an impermeable dielectric molecule in the solvent with a different dielectric constant. The electrostatic free energy in the problem is studied in the Debye-Hückel regime using the analytical Green function that is calculated in the paper. Using this electrostatic free energy, we study the electrostatic contribution to the twist rigidity of a double stranded helical molecule such as a DNA and an actin filament. The dependence of the electrostatic twist rigidity of the molecule to the dielectric inhomogeneity, structural parameters, and the salt concentration is studied. It is shown that, depending on the parameters, the electrostatic twist rigidity could be positive or negative.

  19. Twist operator correlation functions in O(n) loop models

    International Nuclear Information System (INIS)

    Simmons, Jacob J H; Cardy, John

    2009-01-01

    Using conformal field theoretic methods we calculate correlation functions of geometric observables in the loop representation of the O(n) model at the critical point. We focus on correlation functions containing twist operators, combining these with anchored loops, boundaries with SLE processes and with double SLE processes. We focus further upon n = 0, representing self-avoiding loops, which corresponds to a logarithmic conformal field theory (LCFT) with c = 0. In this limit the twist operator plays the role of a 0-weight indicator operator, which we verify by comparison with known examples. Using the additional conditions imposed by the twist operator null states, we derive a new explicit result for the probabilities that an SLE 8/3 winds in various ways about two points in the upper half-plane, e.g. that the SLE passes to the left of both points. The collection of c = 0 logarithmic CFT operators that we use deriving the winding probabilities is novel, highlighting a potential incompatibility caused by the presence of two distinct logarithmic partners to the stress tensor within the theory. We argue that both partners do appear in the theory, one in the bulk and one on the boundary and that the incompatibility is resolved by restrictive bulk-boundary fusion rules

  20. Twisted classical Poincare algebras

    International Nuclear Information System (INIS)

    Lukierski, J.; Ruegg, H.; Tolstoy, V.N.; Nowicki, A.

    1993-11-01

    We consider the twisting of Hopf structure for classical enveloping algebra U(g), where g is the inhomogeneous rotations algebra, with explicite formulae given for D=4 Poincare algebra (g=P 4 ). The comultiplications of twisted U F (P 4 ) are obtained by conjugating primitive classical coproducts by F element of U(c)xU(c), where c denotes any Abelian subalgebra of P 4 , and the universal R-matrices for U F (P 4 ) are triangular. As an example we show that the quantum deformation of Poincare algebra recently proposed by Chaichian and Demiczev is a twisted classical Poincare algebra. The interpretation of twisted Poincare algebra as describing relativistic symmetries with clustered 2-particle states is proposed. (orig.)

  1. HOMFLY for twist knots and exclusive Racah matrices in representation [333

    Science.gov (United States)

    Morozov, A.

    2018-03-01

    Next step is reported in the program of Racah matrices extraction from the differential expansion of HOMFLY polynomials for twist knots: from the double-column rectangular representations R = [ rr ] to a triple-column and triple-hook R = [ 333 ]. The main new phenomenon is the deviation of the particular coefficient f[ 332 ][ 21 ] from the corresponding skew dimension, what opens a way to further generalizations.

  2. Generalised twisted partition functions

    CERN Document Server

    Petkova, V B

    2001-01-01

    We consider the set of partition functions that result from the insertion of twist operators compatible with conformal invariance in a given 2D Conformal Field Theory (CFT). A consistency equation, which gives a classification of twists, is written and solved in particular cases. This generalises old results on twisted torus boundary conditions, gives a physical interpretation of Ocneanu's algebraic construction, and might offer a new route to the study of properties of CFT.

  3. `Twisted' electrons

    Science.gov (United States)

    Larocque, Hugo; Kaminer, Ido; Grillo, Vincenzo; Leuchs, Gerd; Padgett, Miles J.; Boyd, Robert W.; Segev, Mordechai; Karimi, Ebrahim

    2018-04-01

    Electrons have played a significant role in the development of many fields of physics during the last century. The interest surrounding them mostly involved their wave-like features prescribed by the quantum theory. In particular, these features correctly predict the behaviour of electrons in various physical systems including atoms, molecules, solid-state materials, and even in free space. Ten years ago, new breakthroughs were made, arising from the new ability to bestow orbital angular momentum (OAM) to the wave function of electrons. This quantity, in conjunction with the electron's charge, results in an additional magnetic property. Owing to these features, OAM-carrying, or twisted, electrons can effectively interact with magnetic fields in unprecedented ways and have motivated materials scientists to find new methods for generating twisted electrons and measuring their OAM content. Here, we provide an overview of such techniques along with an introduction to the exciting dynamics of twisted electrons.

  4. Evaluation of single and double centrifugation tube methods for concentrating equine platelets.

    Science.gov (United States)

    Argüelles, D; Carmona, J U; Pastor, J; Iborra, A; Viñals, L; Martínez, P; Bach, E; Prades, M

    2006-10-01

    The aim of this study was to evaluate single and double centrifugation tube methods for concentrating equine platelets. Whole blood samples were collected from clinically normal horses and processed by use of single and double centrifugation tube methods to obtain four platelet concentrates (PCs): PC-A, PC-B, PC-C, and PC-D, which were analyzed using a flow cytometry hematology system for hemogram and additional platelet parameters (mean platelet volume, platelet distribution width, mean platelet component concentration, mean platelet component distribution width). Concentrations of transforming growth factor beta 1 (TGF-beta(1)) were determined in all the samples. Platelet concentrations for PC-A, PC-B, PC-C, and PC-D were 45%, 44%, 71%, and 21% higher, respectively, compared to the same values for citrated whole blood samples. TGF-beta(1) concentrations for PC-A, PC-B, PC-C, and PC-D were 38%, 44%, 44%, and 37% higher, respectively, compared to citrated whole blood sample values. In conclusion, the single and double centrifugation tube methods are reliable methods for concentrating equine platelets and for obtaining potentially therapeutic TGF-beta(1) levels.

  5. Twist-stretch profiles of DNA chains

    Science.gov (United States)

    Zoli, Marco

    2017-06-01

    Helical molecules change their twist number under the effect of a mechanical load. We study the twist-stretch relation for a set of short DNA molecules modeled by a mesoscopic Hamiltonian. Finite temperature path integral techniques are applied to generate a large ensemble of possible configurations for the base pairs of the sequence. The model also accounts for the bending and twisting fluctuations between adjacent base pairs along the molecules stack. Simulating a broad range of twisting conformation, we compute the helix structural parameters by averaging over the ensemble of base pairs configurations. The method selects, for any applied force, the average twist angle which minimizes the molecule’s free energy. It is found that the chains generally over-twist under an applied stretching and the over-twisting is physically associated to the contraction of the average helix diameter, i.e. to the damping of the base pair fluctuations. Instead, assuming that the maximum amplitude of the bending fluctuations may decrease against the external load, the DNA molecule first over-twists for weak applied forces and then untwists above a characteristic force value. Our results are discussed in relation to available experimental information albeit for kilo-base long molecules.

  6. Analysis of twisted tape solutions for cooling of the residual ion dump of the ITER HNB

    Energy Technology Data Exchange (ETDEWEB)

    Ochoa Guamán, Santiago, E-mail: santiago.ochoa@kit.edu [Karlsruhe Institute of Technology (KIT), Institute for Technical Physics, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany); Hanke, Stefan [Karlsruhe Institute of Technology (KIT), Institute for Technical Physics, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany); Sartori, Emanuele; Palma, Mauro Dalla [Consorzio RFX (CNR, ENEA, INFN, Università di Padova, Acciaierie Venete SpA), Corso Stati Uniti 4, 35127 Padua (Italy)

    2016-11-01

    Highlights: • Due to manufacturing deviations, the cooling channels are made by double side drilling. • Twisted tapes with two different thicknesses are necessary for a better cooling performance. • The manufacturing of cooling channels and twisted tapes was demonstrated to be feasible. • The water critical heat flux safety margin is higher than 1.5 for the total channel length. • Geometry optimization shown better cooling performance and higher CHF safety margins. - Abstract: The ITER HNB residual ion dump is exposed to a heat load about 17 MW on the dump panels with a peak power density of 7 MW/m{sup 2}. Water flows through cooling channels, 2 m long and 14 mm diameter, realized by double side deep drilling. Unavoidable manufacturing deviations could generate a discontinuity at the channel length center. It is necessary to verify the influence of issues such as cavitation, fluid stagnation, low boiling margins, among others, in the cooling performance. Assuming worst case conditions, analytical and CFD methods showed a subcooled boiling operation with high safety margins to the water critical heat flux. Additionally, by analysing several thermo-hydraulic parameters, the twisted tape cross sections were optimized. Per cooling channel, two twisted tapes are inserted from the sides of the panels, thus, a study of a separation gap between them at the channel length center presented an optimal distance. This paper demonstrates that common machining techniques and drilling tolerances allow the manufacturing of panels able to withstand safely the required beam operation heat loads, even under worst case operation scenarios.

  7. Noncommutative geometry and twisted conformal symmetry

    International Nuclear Information System (INIS)

    Matlock, Peter

    2005-01-01

    The twist-deformed conformal algebra is constructed as a Hopf algebra with twisted coproduct. This allows for the definition of conformal symmetry in a noncommutative background geometry. The twisted coproduct is reviewed for the Poincare algebra and the construction is then extended to the full conformal algebra. The case of Moyal-type noncommutativity of the coordinates is considered. It is demonstrated that conformal invariance need not be viewed as incompatible with noncommutative geometry; the noncommutativity of the coordinates appears as a consequence of the twisting, as has been shown in the literature in the case of the twisted Poincare algebra

  8. TEK twisted gradient flow running coupling

    CERN Document Server

    Pérez, Margarita García; Keegan, Liam; Okawa, Masanori

    2014-01-01

    We measure the running of the twisted gradient flow coupling in the Twisted Eguchi-Kawai (TEK) model, the SU(N) gauge theory on a single site lattice with twisted boundary conditions in the large N limit.

  9. On the twist-2 and twist-3 contributions to the spin-dependent electroweak structure functions

    International Nuclear Information System (INIS)

    Bluemlein, J.; Kochelev, N.

    1997-01-01

    The twist-2 and twist-3 contributions of the polarized deep-inelastic structure functions are calculated both for neutral and charged current interactions using the operator product expansion in lowest order in QCD. The relations between the different structure functions are determined. New integral relations are derived between the twist-2 contributions of the structure functions g 3 (x,Q 2 ) and g 5 (x,Q 2 ) and between combinations of the twist-3 contributions to the structure functions g 2 (x,Q 2 ) and g 3 (x,Q 2 ). The sum rules for polarized deep-inelastic scattering are discussed in detail. (orig.)

  10. Twisted rudder for reducing fuel-oil consumption

    Directory of Open Access Journals (Sweden)

    Jung-Hun Kim

    2014-09-01

    Full Text Available Three twisted rudders fit for large container ships have been developed; 1 the Z-twisted rudder that is an asymmetry type taking into consideration incoming flow angles of the propeller slipstream, 2 the ZB-twisted rudder with a rudder bulb added onto the Z-twisted rudder, and 3 the ZB-F twisted rudder with a rudder fin attached to the ZB-twisted rudder. The twisted rudders have been designed computationally with the hydrodynamic characteristics in a self-propulsion condition in mind. The governing equation is the Navier-Stokes equations in an unsteady turbulent flow. The turbulence model applied is the Reynolds stress. The calculation was carried out in towing and self-propulsion conditions. The sliding mesh technique was employed to simulate the flow around the propeller. The speed performances of the ship with the twisted rudders were verified through model tests in a towing tank. The twisted versions showed greater performance driven by increased hull efficiency from less thrust deduction fraction and more effective wake fraction and decreased propeller rotating speed.

  11. Partial twisting for scalar mesons

    International Nuclear Information System (INIS)

    Agadjanov, Dimitri; Meißner, Ulf-G.; Rusetsky, Akaki

    2014-01-01

    The possibility of imposing partially twisted boundary conditions is investigated for the scalar sector of lattice QCD. According to the commonly shared belief, the presence of quark-antiquark annihilation diagrams in the intermediate state generally hinders the use of the partial twisting. Using effective field theory techniques in a finite volume, and studying the scalar sector of QCD with total isospin I=1, we however demonstrate that partial twisting can still be performed, despite the fact that annihilation diagrams are present. The reason for this are delicate cancellations, which emerge due to the graded symmetry in partially quenched QCD with valence, sea and ghost quarks. The modified Lüscher equation in case of partial twisting is given

  12. Candy twists as an alternative to the glucola beverage in gestational diabetes mellitus screening.

    Science.gov (United States)

    Racusin, Diana A; Antony, Kathleen; Showalter, Lori; Sharma, Susan; Haymond, Morey; Aagaard, Kjersti M

    2015-04-01

    Screening for gestational diabetes mellitus commonly uses an oral glucose challenge test with a 50-g glucola beverage and subsequent venous puncture. However, up to 30% of pregnant women report significant side-effects, and the beverage is costly. We hypothesized that equivalent glucose loads could be achieved from a popular candy twist (Twizzlers; The Hershey Company, Hershey, PA) and tested it as cost-effective, tolerable alternative with a test of equivalency. The glucose equivalent of the 50-g glucola was calculated as 10 candy twists. We initially used a triple crossover design in nonpregnant patients whereby each subject served as her own control; this ensured the safety and equivalency of this load before using it among pregnant subjects. We then recruited pregnant women with an abnormal screening at 1 hour (glucose challenge test) in a double crossover design study. Subjects consumed 10 candy twists with a 1-hour venous blood glucose assessment. All subjects subsequently completed the confirmatory 3-hour glucose tolerance test. Sensitivity, specificity, positive predictive values, negative predictive values, false-referral rates, and detection rates were calculated. At ≥130 mg/dL, the sensitivity (100%) was the same for candy twists and glucola. However, the false-referral rate (82% vs 90%), positive predictive value (18% vs 10%), and detection rate (18% vs 10%) were improved for candy twists when compared with the 50-g glucola beverage. Our results indicate that strawberry-flavored candy twists are potentially an equally effective screening test, compared with the gold standard glucola beverage but lead to fewer false-positive screens and therefore could be a cost-effective alternative. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Double Dirac cones in phononic crystals

    KAUST Repository

    Li, Yan

    2014-07-07

    A double Dirac cone is realized at the center of the Brillouin zone of a two-dimensional phononic crystal (PC) consisting of a triangular array of core-shell-structure cylinders in water. The double Dirac cone is induced by the accidental degeneracy of two double-degenerate Bloch states. Using a perturbation method, we demonstrate that the double Dirac cone is composed of two identical and overlapping Dirac cones whose linear slopes can also be accurately predicted from the method. Because the double Dirac cone occurs at a relatively low frequency, a slab of the PC can be mapped onto a slab of zero refractive index material by using a standard retrieval method. Total transmission without phase change and energy tunneling at the double Dirac point frequency are unambiguously demonstrated by two examples. Potential applications can be expected in diverse fields such as acoustic wave manipulations and energy flow control.

  14. Double Dirac cones in phononic crystals

    KAUST Repository

    Li, Yan; Wu, Ying; Mei, Jun

    2014-01-01

    A double Dirac cone is realized at the center of the Brillouin zone of a two-dimensional phononic crystal (PC) consisting of a triangular array of core-shell-structure cylinders in water. The double Dirac cone is induced by the accidental degeneracy of two double-degenerate Bloch states. Using a perturbation method, we demonstrate that the double Dirac cone is composed of two identical and overlapping Dirac cones whose linear slopes can also be accurately predicted from the method. Because the double Dirac cone occurs at a relatively low frequency, a slab of the PC can be mapped onto a slab of zero refractive index material by using a standard retrieval method. Total transmission without phase change and energy tunneling at the double Dirac point frequency are unambiguously demonstrated by two examples. Potential applications can be expected in diverse fields such as acoustic wave manipulations and energy flow control.

  15. Photophysics of internal twisting

    International Nuclear Information System (INIS)

    Heisel, F.; Miehe, J.A.; Lippert, E.; Rettig, W.; Bonacic-Koutecky, V.

    1987-01-01

    The formation and characteristics of the ''twisted intermolecular charge transfer'' is studied. Basic concepts on dual fluorescence, steady-state fluorescence, kinetic investigations and cage effects are discussed. The theoretical treatment on the electronic structure of the bonded π - donor - π acceptor pairs is outlined. The two-electron, two-orbital model, the ab initio CI models of simple double, charged and dative π - bonds as well as complex dative π - bonds and the origin of the dual fluorescence of 9.9'-Bianthryl are shown. Concerning the stochastic description of chemical reactions, Master equation, Markov, Birth-Death and Diffusion processes, Kramers-Moyal expansion, Langevin equation, Kramers' approach to steady-state rates of reaction and its extension to non-Markovian processes, and also unimolecular reactions in the absence of potential barrier are considered. Experimental results and interpretation on dynamics of DMABN in the excited state, kinetics of other dialkylanilines, extended donor-acceptor systems with anomalous fluorescence and donor-acceptor systems without anomalous fluorescence are given

  16. Experimental investigation of heat transfer augmentation inside double pipe heat exchanger equipped with reduced width twisted tapes inserts using polymeric nanofluid

    Science.gov (United States)

    Hazbehian, Mohammad; Maddah, Heydar; Mohammadiun, Hamid; Alizadeh, Mostafa

    2016-11-01

    In this study, we report a further enhancement in heat transfer coefficients of base fluid in combination with structural modifications of tape inserts. Polyvinyl Alcohol and TiO2 with mean diameter of 15 nm were chosen as base fluid and nano-particles, respectively. The experiments are carried out in plain tube with four longitudinal internal fins and reduced width twisted tape (RWTT) inserts of twist ratio varying form 2-5 and width of 12-16. Experiments are undertaken to determine heat transfer coefficients and friction factor of TiO2/PVA nanofluid up to 2.0 % volume concentration at an average temperature of 30 °C. The investigations are undertaken in the Reynolds number range of 800-30,000 for flow in tubes and with tapes of different width length ratios. The experiments was verified with well-known correlations. The average Nusselt number and friction factor in the tube fitted with the full-length twisted tapes at y/w = 3.0, and 5.0, are respectively 50-130, and 30-95 % higher than those in the plain tube; 90-220 and 100-270 % when the working fluid is nanofluid, respectively. For the reduced width twisted tapes, the heat transfer rate is decreased with decreasing tapes width. The average Nusselt numbers in the tube fitted with the RWTT of 16, 14 and 12 are respectively, 210-390, 190-320 and 170-290 % of that in the plain tube. With the similar trend mentioned above, RWTT with higher width length yield higher thermal enhancement factor in comparison with smaller width. The use of RWTT led to the highest thermal performance factor up to 1.75. Maximum thermal performance factor which was obtained belonged to twists with twist ratio of 2 and width of 16 with φ = 0.5 % and Reynolds number range of 800-30,000.

  17. Analysis list: Twist1 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Twist1 Embryo,Neural + mm9 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Tw...ist1.1.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Twist1.5.tsv http://dbarchive.biosciencedbc....jp/kyushu-u/mm9/target/Twist1.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Twist1.Embryo.tsv,http://dbarchive.bioscien...cedbc.jp/kyushu-u/mm9/colo/Twist1.Neural.tsv http://dbarchive.bioscience...dbc.jp/kyushu-u/mm9/colo/Embryo.gml,http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Neural.gml ...

  18. Modeling and control of active twist aircraft

    Science.gov (United States)

    Cramer, Nicholas Bryan

    The Wright Brothers marked the beginning of powered flight in 1903 using an active twist mechanism as their means of controlling roll. As time passed due to advances in other technologies that transformed aviation the active twist mechanism was no longer used. With the recent advances in material science and manufacturability, the possibility of the practical use of active twist technologies has emerged. In this dissertation, the advantages and disadvantages of active twist techniques are investigated through the development of an aeroelastic modeling method intended for informing the designs of such technologies and wind tunnel testing to confirm the capabilities of the active twist technologies and validate the model. Control principles for the enabling structural technologies are also proposed while the potential gains of dynamic, active twist are analyzed.

  19. Teaching Spatial Awareness for Better Twisting Somersaults.

    Science.gov (United States)

    Hennessy, Jeff T.

    1985-01-01

    The barani (front somersault with one-half twist) and the back somersault with one twist are basic foundation skills necessary for more advanced twisting maneuvers. Descriptions of these movements on a trampoline surface are offered. (DF)

  20. Five-loop anomalous dimension of twist-two operators

    Energy Technology Data Exchange (ETDEWEB)

    Lukowski, T. [Institute of Physics, Jagellonian University, ul. Reymonta 4, 30-059 Krakow (Poland); Rej, A. [Blackett Laboratory, Imperial College, London SW7 2AZ (United Kingdom); Velizhanin, V.N., E-mail: velizh@mail.desy.d [Theoretical Physics Department, Petersburg Nuclear Physics Institute, Orlova Roscha, Gatchina, 188300 St. Petersburg (Russian Federation)

    2010-05-21

    In this article we calculate the five-loop anomalous dimension of twist-two operators in the planar N=4 SYM theory. Firstly, using reciprocity, we derive the contribution of the asymptotic Bethe ansatz. Subsequently, we employ the first finite-size correction for the AdS{sub 5}xS{sup 5} sigma model to determine the wrapping correction. The anomalous dimension found in this way passes all known tests provided by the NLO BFKL equation and double-logarithmic constraints. This result thus furnishes an infinite number of experimental data for testing the veracity of the recently proposed spectral equations for planar AdS/CFT correspondence.

  1. Twist deformations of the supersymmetric quantum mechanics

    Energy Technology Data Exchange (ETDEWEB)

    Castro, P.G.; Chakraborty, B.; Toppan, F., E-mail: pgcastro@cbpf.b, E-mail: biswajit@bose.res.i, E-mail: toppan@cbpf.b [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil); Kuznetsova, Z., E-mail: zhanna.kuznetsova@ufabc.edu.b [Universidade Federal do ABC (UFABC), Santo Andre, SP (Brazil)

    2009-07-01

    The N-extended supersymmetric quantum mechanics is deformed via an abelian twist which preserves the super-Hopf algebra structure of its universal enveloping superalgebra. Two constructions are possible. For even N one can identify the 1D N-extended superalgebra with the fermionic Heisenberg algebra. Alternatively, supersymmetry generators can be realized as operators belonging to the Universal Enveloping Superalgebra of one bosonic and several fermionic oscillators. The deformed system is described in terms of twisted operators satisfying twist deformed (anti)commutators. The main differences between an abelian twist defined in terms of fermionic operators and an abelian twist defined in terms of bosonic operators are discussed. (author)

  2. Ten helical twist angles of B-DNA

    Energy Technology Data Exchange (ETDEWEB)

    Kabsch, W; Sander, C; Trifonov, E N

    1982-01-01

    On the assumption that the twist angles between adjacent base-pairs in the DNA molecule are additive a linear system of 40 equations was derived from experimental measurements of the total twist angles for different pieces of DNA of known sequences. This system of equations is found to be statistically consistent providing a solution for all ten possible twist angles of B-DNA by a least squares fitting procedure. Four of the calculated twist angles were not known before. The other six twist angles calculated are very close to the experimentally measured ones. The data used were obtained by the electrophoretic band-shift method, crystallography and nuclease digestion of DNA adsorbed to mica or Ca-phosphate surface. The validity of the principle of additivity of the twist angles implies that the angle between any particular two base-pairs is a function of only these base-pairs, independent of nearest neighbors.

  3. Double-Twisted Conductive Smart Threads Comprising a Homogeneously and a Gradient-Coated Thread for Multidimensional Flexible Pressure-Sensing Devices

    KAUST Repository

    Tai, Yanlong

    2016-03-17

    Fiber-based, flexible pressure-sensing systems have attracted attention recently due to their promising application as electronic skins. Here, a new kind of flexible pressure-sensing device based on a polydimethylsiloxane membrane instrumented with double-twisted smart threads (DTSTs) is reported. DTSTs are made of two conductive threads obtained by coating cotton threads with carbon nanotubes. One thread is coated with a homogeneous thickness of single-walled carbon nanotubes (SWCNTs) to detect the intensity of an applied load and the other is coated with a graded thickness of SWCNTs to identify the position of the load along the thread. The mechanism and capacity of DTSTs to accurately sense an applied load are systematically analyzed. Results demonstrate that the fabricated 1D, 2D, and 3D sensing devices can be used to predict both the intensity and the position of an applied load. The sensors feature high sensitivity (between ≈0.1% and 1.56% kPa) and tunable resolution, good cycling resilience (>104 cycles), and a short response time (minimum 2.5 Hz). The presented strategy is a viable alternative for the design of simple, low-cost pressure sensors.

  4. ORPLOT.PC: a graphic utility for ORMGEN.PC and ORVIRT.PC

    International Nuclear Information System (INIS)

    Inversini, C.; Bryson, J.W.

    1986-06-01

    ORPLOT.PC is an interactive graphic utility for ORMGEN.PC and ORVIRT.PC. It executes on an IBM PC/XT or PC/AT equipped with hard disk, graphic card, and 512K minimum memory. The program is capable of: (1) displaying finite-element meshes generated by ORMGEN.PC complete with node numbers, element numbers, and boundary conditions; and (2) generating deformed mesh plots, contour plots, line (X-Y) plots, and developed surface plots of ORVIRT.PC output. A zooming feature allows detailed inspection of any subregion. Because simplicity and ease of use were important objectives during program development, all commands are entered interactively using free format. The option of automatic or user-defined scaling for most plots is another convenience. Plot files may be created and written to hard disk for subsequent hardcopy to printer or plotter. 2 refs., 7 figs

  5. Twisted electron-acoustic waves in plasmas

    International Nuclear Information System (INIS)

    Aman-ur-Rehman; Ali, S.; Khan, S. A.; Shahzad, K.

    2016-01-01

    In the paraxial limit, a twisted electron-acoustic (EA) wave is studied in a collisionless unmagnetized plasma, whose constituents are the dynamical cold electrons and Boltzmannian hot electrons in the background of static positive ions. The analytical and numerical solutions of the plasma kinetic equation suggest that EA waves with finite amount of orbital angular momentum exhibit a twist in its behavior. The twisted wave particle resonance is also taken into consideration that has been appeared through the effective wave number q_e_f_f accounting for Laguerre-Gaussian mode profiles attributed to helical phase structures. Consequently, the dispersion relation and the damping rate of the EA waves are significantly modified with the twisted parameter η, and for η → ∞, the results coincide with the straight propagating plane EA waves. Numerically, new features of twisted EA waves are identified by considering various regimes of wavelength and the results might be useful for transport and trapping of plasma particles in a two-electron component plasma.

  6. Single NdPc2 molecules on surfaces. Adsorption, interaction, and molecular magnetism

    International Nuclear Information System (INIS)

    Fahrendorf, Sarah

    2013-01-01

    They have huge potential for application in molecular-spin-transistors, molecular-spinvalves, and molecular quantum computing. SMMs are characterized by high spin ground states with zero-field splitting leading to high relaxation barriers and long relaxation times. A relevant class of molecules are the lanthanide double-decker phthalocyanines (LaPc 2 ) with only one metal atom sandwiched between two organic phthalocyanine (Pc) ligands. For envisaged spintronic applications it is important to understand the interaction between the molecules and the substrate and its influence on the electronic and magnetic properties. The subject of this thesis is the investigation of the adsorbed neodymium double-decker phthalocyanine (NdPc 2 ) by means of low temperature scanning tunneling microscopy and spectroscopy (STM and STS). The molecules are deposited by sublimation onto different substrates. It is observed that a large fraction of the double-decker molecules decomposes during deposition. The decomposition probability strongly depends on the chosen substrate. Therefore it is concluded that the substrate modifies the electronic structure of the molecule leading to a stabilization or destabilization of the molecular entity. Charge transfer from the surface to the molecule is identified as a potential stabilizing mechanism. The electronic and magnetic properties are investigated in detail for adsorbed NdPc 2 molecules on Cu(100). The results of the experimental study are compared to state-of-the-art density functional theory calculations performed by our colleagues from the Peter Gruenberg Institute (PGI-1) at the Forschungszentrum Juelich. Interestingly, the lower Pc ring of the molecule hybridizes intensely with the substrate leading to strong chemisorption of the molecule, while the upper Pc ring keeps its molecular type electronic states, which can be energetically shifted by an external electric field. Importantly, it is possible to get direct access to the spin

  7. Remarks on twisted noncommutative quantum field theory

    Energy Technology Data Exchange (ETDEWEB)

    Zahn, J. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik

    2006-04-15

    We review recent results on twisted noncommutative quantum field theory by embedding it into a general framework for the quantization of systems with a twisted symmetry. We discuss commutation relations in this setting and show that the twisted structure is so rigid that it is hard to derive any predictions, unless one gives up general principles of quantum theory. It is also shown that the twisted structure is not responsible for the presence or absence of UV/IR-mixing, as claimed in the literature. (Orig.)

  8. Morphing wing structure with controllable twist based on adaptive bending-twist coupling

    Science.gov (United States)

    Raither, Wolfram; Heymanns, Matthias; Bergamini, Andrea; Ermanni, Paolo

    2013-06-01

    A novel semi-passive morphing airfoil concept based on variable bending-twist coupling induced by adaptive shear center location and torsional stiffness is presented. Numerical parametric studies and upscaling show that the concept relying on smart materials permits effective twist control while offering the potential of being lightweight and energy efficient. By means of an experimental characterization of an adaptive beam and a scaled adaptive wing structure, effectiveness and producibility of the structural concept are demonstrated.

  9. Morphing wing structure with controllable twist based on adaptive bending–twist coupling

    International Nuclear Information System (INIS)

    Raither, Wolfram; Heymanns, Matthias; Ermanni, Paolo; Bergamini, Andrea

    2013-01-01

    A novel semi-passive morphing airfoil concept based on variable bending–twist coupling induced by adaptive shear center location and torsional stiffness is presented. Numerical parametric studies and upscaling show that the concept relying on smart materials permits effective twist control while offering the potential of being lightweight and energy efficient. By means of an experimental characterization of an adaptive beam and a scaled adaptive wing structure, effectiveness and producibility of the structural concept are demonstrated. (paper)

  10. Conical twist fields and null polygonal Wilson loops

    Science.gov (United States)

    Castro-Alvaredo, Olalla A.; Doyon, Benjamin; Fioravanti, Davide

    2018-06-01

    Using an extension of the concept of twist field in QFT to space-time (external) symmetries, we study conical twist fields in two-dimensional integrable QFT. These create conical singularities of arbitrary excess angle. We show that, upon appropriate identification between the excess angle and the number of sheets, they have the same conformal dimension as branch-point twist fields commonly used to represent partition functions on Riemann surfaces, and that both fields have closely related form factors. However, we show that conical twist fields are truly different from branch-point twist fields. They generate different operator product expansions (short distance expansions) and form factor expansions (large distance expansions). In fact, we verify in free field theories, by re-summing form factors, that the conical twist fields operator product expansions are correctly reproduced. We propose that conical twist fields are the correct fields in order to understand null polygonal Wilson loops/gluon scattering amplitudes of planar maximally supersymmetric Yang-Mills theory.

  11. Renormalization constants for 2-twist operators in twisted mass QCD

    International Nuclear Information System (INIS)

    Alexandrou, C.; Constantinou, M.; Panagopoulos, H.; Stylianou, F.; Korzec, T.

    2011-01-01

    Perturbative and nonperturbative results on the renormalization constants of the fermion field and the twist-2 fermion bilinears are presented with emphasis on the nonperturbative evaluation of the one-derivative twist-2 vector and axial-vector operators. Nonperturbative results are obtained using the twisted mass Wilson fermion formulation employing two degenerate dynamical quarks and the tree-level Symanzik improved gluon action. The simulations have been performed for pion masses in the range of about 450-260 MeV and at three values of the lattice spacing a corresponding to β=3.9, 4.05, 4.20. Subtraction of O(a 2 ) terms is carried out by performing the perturbative evaluation of these operators at 1-loop and up to O(a 2 ). The renormalization conditions are defined in the RI ' -MOM scheme, for both perturbative and nonperturbative results. The renormalization factors, obtained for different values of the renormalization scale, are evolved perturbatively to a reference scale set by the inverse of the lattice spacing. In addition, they are translated to MS at 2 GeV using 3-loop perturbative results for the conversion factors.

  12. How to Twist a Knot

    DEFF Research Database (Denmark)

    Randrup, Thomas; Røgen, Peter

    1997-01-01

    is an invariant of ambient isotopy measuring the topological twist of the closed strip. We classify closed strips in euclidean 3-space by their knots and their twisting number. We prove that this classification exactly divides closed strips into isotopy classes. Using this classification we point out how some...

  13. Transverse kink oscillations in the presence of twist

    Science.gov (United States)

    Terradas, J.; Goossens, M.

    2012-12-01

    Context. Magnetic twist is thought to play an important role in coronal loops. The effects of magnetic twist on stable magnetohydrodynamic (MHD) waves is poorly understood because they are seldom studied for relevant cases. Aims: The goal of this work is to study the fingerprints of magnetic twist on stable transverse kink oscillations. Methods: We numerically calculated the eigenmodes of propagating and standing MHD waves for a model of a loop with magnetic twist. The azimuthal component of the magnetic field was assumed to be small in comparison to the longitudinal component. We did not consider resonantly damped modes or kink instabilities in our analysis. Results: For a nonconstant twist the frequencies of the MHD wave modes are split, which has important consequences for standing waves. This is different from the degenerated situation for equilibrium models with constant twist, which are characterised by an azimuthal component of the magnetic field that linearly increases with the radial coordinate. Conclusions: In the presence of twist standing kink solutions are characterised by a change in polarisation of the transverse displacement along the tube. For weak twist, and in the thin tube approximation, the frequency of standing modes is unaltered and the tube oscillates at the kink speed of the corresponding straight tube. The change in polarisation is linearly proportional to the degree of twist. This has implications with regard to observations of kink modes, since the detection of this variation in polarisation can be used as an indirect method to estimate the twist in oscillating loops.

  14. Controlled Conjugated Backbone Twisting for an Increased Open-Circuit Voltage while Having a High Short-Circuit Current in Poly(hexylthiophene) Derivatives

    KAUST Repository

    Ko, Sangwon

    2012-03-21

    Conjugated polymers with nearly planar backbones have been the most commonly investigated materials for organic-based electronic devices. More twisted polymer backbones have been shown to achieve larger open-circuit voltages in solar cells, though with decreased short-circuit current densities. We systematically impose twists within a family of poly(hexylthiophene)s and examine their influence on the performance of polymer:fullerene bulk heterojunction (BHJ) solar cells. A simple chemical modification concerning the number and placement of alkyl side chains along the conjugated backbone is used to control the degree of backbone twisting. Density functional theory calculations were carried out on a series of oligothiophene structures to provide insights on how the sterically induced twisting influences the geometric, electronic, and optical properties. Grazing incidence X-ray scattering measurements were performed to investigate how the thin-film packing structure was affected. The open-circuit voltage and charge-transfer state energy of the polymer:fullerene BHJ solar cells increased substantially with the degree of twist induced within the conjugated backbone-due to an increase in the polymer ionization potential-while the short-circuit current decreased as a result of a larger optical gap and lower hole mobility. A controlled, moderate degree of twist along the poly(3,4-dihexyl-2,2′:5′,2′′- terthiophene) (PDHTT) conjugated backbone led to a 19% enhancement in the open-circuit voltage (0.735 V) vs poly(3-hexylthiophene)-based devices, while similar short-circuit current densities, fill factors, and hole-carrier mobilities were maintained. These factors resulted in a power conversion efficiency of 4.2% for a PDHTT:[6,6]-phenyl-C 71-butyric acid methyl ester (PC 71BM) blend solar cell without thermal annealing. This simple approach reveals a molecular design avenue to increase open-circuit voltage while retaining the short-circuit current. © 2012 American

  15. Controlled conjugated backbone twisting for an increased open-circuit voltage while having a high short-circuit current in poly(hexylthiophene) derivatives.

    Science.gov (United States)

    Ko, Sangwon; Hoke, Eric T; Pandey, Laxman; Hong, Sanghyun; Mondal, Rajib; Risko, Chad; Yi, Yuanping; Noriega, Rodrigo; McGehee, Michael D; Brédas, Jean-Luc; Salleo, Alberto; Bao, Zhenan

    2012-03-21

    Conjugated polymers with nearly planar backbones have been the most commonly investigated materials for organic-based electronic devices. More twisted polymer backbones have been shown to achieve larger open-circuit voltages in solar cells, though with decreased short-circuit current densities. We systematically impose twists within a family of poly(hexylthiophene)s and examine their influence on the performance of polymer:fullerene bulk heterojunction (BHJ) solar cells. A simple chemical modification concerning the number and placement of alkyl side chains along the conjugated backbone is used to control the degree of backbone twisting. Density functional theory calculations were carried out on a series of oligothiophene structures to provide insights on how the sterically induced twisting influences the geometric, electronic, and optical properties. Grazing incidence X-ray scattering measurements were performed to investigate how the thin-film packing structure was affected. The open-circuit voltage and charge-transfer state energy of the polymer:fullerene BHJ solar cells increased substantially with the degree of twist induced within the conjugated backbone--due to an increase in the polymer ionization potential--while the short-circuit current decreased as a result of a larger optical gap and lower hole mobility. A controlled, moderate degree of twist along the poly(3,4-dihexyl-2,2':5',2''-terthiophene) (PDHTT) conjugated backbone led to a 19% enhancement in the open-circuit voltage (0.735 V) vs poly(3-hexylthiophene)-based devices, while similar short-circuit current densities, fill factors, and hole-carrier mobilities were maintained. These factors resulted in a power conversion efficiency of 4.2% for a PDHTT:[6,6]-phenyl-C(71)-butyric acid methyl ester (PC(71)BM) blend solar cell without thermal annealing. This simple approach reveals a molecular design avenue to increase open-circuit voltage while retaining the short-circuit current.

  16. WORKSHOP: Let's twist again..

    Energy Technology Data Exchange (ETDEWEB)

    Villalobos Baillie, Orlando

    1988-12-15

    In the quantum chromodynamics (QCD) candidate theory of interquark forces, calculations involve summing the effects from many different possible quark/gluon interactions. In addition to the 'leading term' frequently used as the basis for QCD calculations, additional contributions — so-called 'higher twists' — are modulated by powers of kinematical factors. An illuminating international workshop to discuss higher twist QCD was held at the College de France, Paris, from 21-23 September.

  17. DVCS amplitude with kinematical twist-3 terms

    International Nuclear Information System (INIS)

    Radyushkin, A.V.; Weiss, C.

    2000-01-01

    The authors compute the amplitude of deeply virtual Compton scattering (DVCS) using the calculus of QCD string operators in coordinate representation. To restore the electromagnetic gauge invariance (transversality) of the twist-2 amplitude they include the operators of twist-3 which appear as total derivatives of twist-2 operators. The results are equivalent to a Wandzura-Wilczek approximation for twist-3 skewed parton distributions. They find that this approximation gives a finite result for the amplitude of a longitudinally polarized virtual photon, while the amplitude for transverse polarization is divergent, i.e., factorization breaks down in this term

  18. Gauge symmetry, T-duality and doubled geometry

    International Nuclear Information System (INIS)

    Hull, C.M.

    2007-11-01

    String compactifications with T-duality twists are revisited and the gauge algebra of the dimensionally reduced theories calculated. These reductions can be viewed as string theory on T-fold backgrounds, and can be formulated in a 'doubled space' in which each circle is supplemented by a T-dual circle to construct a geometry which is a doubled torus bundle over a circle. We discuss a conjectured extension to include T-duality on the base circle, and propose the introduction of a dual base coordinate, to give a doubled space which is locally the group manifold of the gauge group. Special cases include those in which the doubled group is a Drinfel'd double. This gives a framework to discuss backgrounds that are not even locally geometric. (orig.)

  19. Single NdPc{sub 2} molecules on surfaces. Adsorption, interaction, and molecular magnetism

    Energy Technology Data Exchange (ETDEWEB)

    Fahrendorf, Sarah

    2013-01-24

    They have huge potential for application in molecular-spin-transistors, molecular-spinvalves, and molecular quantum computing. SMMs are characterized by high spin ground states with zero-field splitting leading to high relaxation barriers and long relaxation times. A relevant class of molecules are the lanthanide double-decker phthalocyanines (LaPc{sub 2}) with only one metal atom sandwiched between two organic phthalocyanine (Pc) ligands. For envisaged spintronic applications it is important to understand the interaction between the molecules and the substrate and its influence on the electronic and magnetic properties. The subject of this thesis is the investigation of the adsorbed neodymium double-decker phthalocyanine (NdPc{sub 2}) by means of low temperature scanning tunneling microscopy and spectroscopy (STM and STS). The molecules are deposited by sublimation onto different substrates. It is observed that a large fraction of the double-decker molecules decomposes during deposition. The decomposition probability strongly depends on the chosen substrate. Therefore it is concluded that the substrate modifies the electronic structure of the molecule leading to a stabilization or destabilization of the molecular entity. Charge transfer from the surface to the molecule is identified as a potential stabilizing mechanism. The electronic and magnetic properties are investigated in detail for adsorbed NdPc{sub 2} molecules on Cu(100). The results of the experimental study are compared to state-of-the-art density functional theory calculations performed by our colleagues from the Peter Gruenberg Institute (PGI-1) at the Forschungszentrum Juelich. Interestingly, the lower Pc ring of the molecule hybridizes intensely with the substrate leading to strong chemisorption of the molecule, while the upper Pc ring keeps its molecular type electronic states, which can be energetically shifted by an external electric field. Importantly, it is possible to get direct access to the

  20. Processing mechanics of alternate twist ply (ATP) yarn technology

    Science.gov (United States)

    Elkhamy, Donia Said

    Ply yarns are important in many textile manufacturing processes and various applications. The primary process used for producing ply yarns is cabling. The speed of cabling is limited to about 35m/min. With the world's increasing demands of ply yarn supply, cabling is incompatible with today's demand activated manufacturing strategies. The Alternate Twist Ply (ATP) yarn technology is a relatively new process for producing ply yarns with improved productivity and flexibility. This technology involves self plying of twisted singles yarn to produce ply yarn. The ATP process can run more than ten times faster than cabling. To implement the ATP process to produce ply yarns there are major quality issues; uniform Twist Profile and yarn Twist Efficiency. The goal of this thesis is to improve these issues through process modeling based on understanding the physics and processing mechanics of the ATP yarn system. In our study we determine the main parameters that control the yarn twist profile. Process modeling of the yarn twist across different process zones was done. A computational model was designed to predict the process parameters required to achieve a square wave twist profile. Twist efficiency, a measure of yarn torsional stability and bulk, is determined by the ratio of ply yarn twist to singles yarn twist. Response Surface Methodology was used to develop the processing window that can reproduce ATP yarns with high twist efficiency. Equilibrium conditions of tensions and torques acting on the yarns at the self ply point were analyzed and determined the pathway for achieving higher twist efficiency. Mechanistic modeling relating equilibrium conditions to the twist efficiency was developed. A static tester was designed to zoom into the self ply zone of the ATP yarn. A computer controlled, prototypic ATP machine was constructed and confirmed the mechanistic model results. Optimum parameters achieving maximum twist efficiency were determined in this study. The

  1. Development and operation of a novel PC-based high speed beam telescope for particle tracking using double sided silicon microstrip detectors

    International Nuclear Information System (INIS)

    Treis, J.

    2002-08-01

    A PC based high speed silicon microstrip beam telescope consisting of several independent modules is presented. Every module contains an AC-coupled double sided silicon microstrip sensor and a complete set of analog and digital signal processing electronics. A digital bus connects the modules with the DAQ PC. A trigger logic unit coordinates the operation of all modules of the telescope. The system architecture allows easy integration of any kind of device under test into the data acquisition chain. Signal digitization, pedestal correction, hit detection and zero suppression are done by hardware inside the modules, so that the amount of data per event is reduced by a factor of 80 compared to conventional readout systems. In combination with a two level data acquisition scheme, this allows event rates up to 7.6 kHz. This is a factor of 40 faster than conventional VME based beam telescopes while comparable analog performance is maintained achieving signal to noise ratios of up to 70:1. The telescope has been tested in the SPS testbeam at CERN. It has been adopted as the reference instrument for testbeam studies for the ATLAS pixel detector development. (orig.)

  2. Twist operators in N=4 beta-deformed theory

    NARCIS (Netherlands)

    de Leeuw, M.; Łukowski, T.

    2010-01-01

    In this paper we derive both the leading order finite size corrections for twist-2 and twist-3 operators and the next-to-leading order finite-size correction for twist-2 operators in beta-deformed SYM theory. The obtained results respect the principle of maximum transcendentality as well as

  3. Higher twist contributions to deep-inelastic structure functions

    International Nuclear Information System (INIS)

    Bluemlein, J.; Boettcher, H.

    2008-07-01

    We report on a recent extraction of the higher twist contributions to the deep inelastic structure functions F ep,ed 2 (x,Q 2 ) in the large x region. It is shown that the size of the extracted higher twist contributions is strongly correlated with the higher order corrections applied to the leading twist part. A gradual lowering of the higher twist contributions going from NLO to N 4 LO is observed, where in the latter case only the leading large x terms were considered. (orig.)

  4. A novel role for Twist-1 in pulp homeostasis.

    Science.gov (United States)

    Galler, K M; Yasue, A; Cavender, A C; Bialek, P; Karsenty, G; D'Souza, R N

    2007-10-01

    The molecular mechanisms that maintain the equilibrium of odontoblast progenitor cells in dental pulp are unknown. Here we tested whether homeostasis in dental pulp is modulated by Twist-1, a nuclear protein that partners with Runx2 during osteoblast differentiation. Our analysis of Twist-1(+/-) mice revealed phenotypic changes that involved an earlier onset of dentin matrix formation, increased alkaline phosphatase activity, and pulp stones within the pulp. RT-PCR analyses revealed Twist-1 expression in several adult organs, including pulp. Decreased levels of Twist-1 led to higher levels of type I collagen and Dspp gene expression in perivascular cells associated with the pulp stones. In mice heterozygous for both Twist-1 and Runx2 inactivation, the phenotype of pulp stones appeared completely rescued. These findings suggest that Twist-1 plays a key role in restraining odontoblast differentiation, thus maintaining homeostasis in dental pulp. Furthermore, Twist-1 functions in dental pulp are dependent on its interaction with Runx2.

  5. Gauge symmetry, T-duality and doubled geometry

    Energy Technology Data Exchange (ETDEWEB)

    Hull, C.M. [Imperial College London (United Kingdom). Inst. for Mathematical Sciences]|[Imperial College London (United Kingdom). Blackett Laboratory; Reid-Edwards, R.A. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik]|[Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2007-11-15

    String compactifications with T-duality twists are revisited and the gauge algebra of the dimensionally reduced theories calculated. These reductions can be viewed as string theory on T-fold backgrounds, and can be formulated in a 'doubled space' in which each circle is supplemented by a T-dual circle to construct a geometry which is a doubled torus bundle over a circle. We discuss a conjectured extension to include T-duality on the base circle, and propose the introduction of a dual base coordinate, to give a doubled space which is locally the group manifold of the gauge group. Special cases include those in which the doubled group is a Drinfel'd double. This gives a framework to discuss backgrounds that are not even locally geometric. (orig.)

  6. SpaceTwist

    DEFF Research Database (Denmark)

    Yiu, Man Lung; Jensen, Christian Søndergaard; Xuegang, Huang

    2008-01-01

    -based matching generally fall short in offering practical query accuracy guarantees. Our proposed framework, called SpaceTwist, rectifies these shortcomings for k nearest neighbor (kNN) queries. Starting with a location different from the user's actual location, nearest neighbors are retrieved incrementally...

  7. Magnetization Modeling of Twisted Superconducting Filaments

    CERN Document Server

    Satiramatekul, T; Devred, Arnaud; Leroy, Daniel

    2007-01-01

    This paper presents a new Finite Element numerical method to analyze the coupling between twisted filaments in a superconducting multifilament composite wire. To avoid the large number of elements required by a 3D code, the proposed method makes use of the energy balance principle in a 2D code. The relationship between superconductor critical current density and local magnetic flux density is implemented in the program for the Bean and modified Kim models. The modeled wire is made up of six filaments twisted together and embedded in a lowresistivity matrix. Computations of magnetization cycle and of the electric field pattern have been performed for various twist pitch values in the case of a pure copper matrix. The results confirm that the maximum magnetization depends on the matrix conductivity, the superconductor critical current density, the applied field frequency, and the filament twist pitch. The simulations also lead to a practical criterion for wire design that can be used to assess whether or not th...

  8. Studies on the separation between higher-twist and minimum-twist in the photoproduction experiment WA69 at the CERN-OMEGA spectrometer

    International Nuclear Information System (INIS)

    Kingler, J.

    1990-01-01

    A Lund type Monte Carlo program (LUCIFER) is used to describe in perturbative QCD the pointlike component of the photon interacting on a hydrogen target. Kinematical and topological variables are developed to enhance higher twist events on the lowest order minimum twist background. The emphasis is laid on π ± , K ± higher twist mesons. (orig.)

  9. PC communication

    International Nuclear Information System (INIS)

    Oh, Jae Cheol

    1992-03-01

    This text book is comprised of five charters, which is about PC communication for beginners who need to learn manners and how to use Ketel and PC serve. So it introduces first, conception of PC and precautions on using PC communication, second, preparation for PC communication with Modem, its program, install, kinds of protocol and how to use protocol, third directions of emulator of PC communication and super session, fourth, instruction of Ketel with join and access, basic command of Ketel, list of Ketel's menu, Ketel editor, service guide, directions of News service, Stock and bond service business and economic figures, exchange rate and interest rate, tax culture and leisure, Ketel BBS service and posting. The last part has a instruction of PC-serve about join, basic command of PC-serve, service guide and practical guideline.

  10. PC communication

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Jae Cheol

    1992-03-15

    This text book is comprised of five charters, which is about PC communication for beginners who need to learn manners and how to use Ketel and PC serve. So it introduces first, conception of PC and precautions on using PC communication, second, preparation for PC communication with Modem, its program, install, kinds of protocol and how to use protocol, third directions of emulator of PC communication and super session, fourth, instruction of Ketel with join and access, basic command of Ketel, list of Ketel's menu, Ketel editor, service guide, directions of News service, Stock and bond service business and economic figures, exchange rate and interest rate, tax culture and leisure, Ketel BBS service and posting. The last part has a instruction of PC-serve about join, basic command of PC-serve, service guide and practical guideline.

  11. Flow structure and heat transfer in a square duct fitted with dual/quadruple twisted-tapes: Influence of tape configuration

    International Nuclear Information System (INIS)

    Eiamsa-ard, S.; Changcharoen, W.

    2015-01-01

    Numerical predictions reported of thermohydraulic characteristics of square ducts equipped with dual and quadruple twisted tapes (DTs and QTs) with different configurations. The studied cases include (1) dual co-tapes (Co-DTs), (2) dual counter-tapes (C-DTs), (3) diagonal dual counter-tapes (C-DDTs), (4) diagonal dual co-tapes (Co-DDTs), (5) quadruple co-tapes (Co-QTs), (6) quadruple counter tapes (CC-QTs) and (7) quadruple counter-tapes (PC-QTs). The results of these cases are compared with those of a smooth duct (a duct without tape insert) and also the one with a single tape (ST). The prediction involves using the RNG k-ε turbulent model under constant wall heat flux condition in the turbulent flow regime for the Reynolds number ranging from 6000 to 14000. The prediction indicates that thermohydraulic characteristics in ducts with twisted tape are strongly dependent on number and configuration of tapes. However, the influence of tape number is more significant than that of tape configuration. Heat transfer and friction increase as tape number increases. QTs offer superior heat transfer to DTs but their thermal performance factors are lower. For the tape inserts determined, DTs with diagonal configuration (Co-DDTs and C-DDTs) is the best design as the tapes offer the best thermal performance. The highest thermal performance factors given by Co-DTs, Co-DDTs, C-DTs, C-DDTs, Co-QTs, PC-QTs and CC-QTs, are around 1.21, 1.35, 1.25, 1.38, 1.08, 1.18, and 1.22, respectively

  12. Simulating QCD at the physical point with Nf=2 Wilson twisted mass fermions at maximal twist

    International Nuclear Information System (INIS)

    Abdel-Rehim, A.; Alexandrou, C.; Cyprus Univ. Nicosia; Burger, F.

    2015-12-01

    We present simulations of QCD using N f =2 dynamical Wilson twisted mass lattice QCD with physical value of the pion mass and at one value of the lattice spacing. Such simulations at a∼0.09 fm became possible by adding the clover term to the action. While O(a) improvement is still guaranteed by Wilson twisted mass fermions at maximal twist, the introduction of the clover term reduces O(a 2 ) cutoff effects related to isospin symmetry breaking. We give results for a set of phenomenologically interesting observables like pseudo-scalar masses and decay constants, quark masses and the anomalous magnetic moments of leptons. We mostly find remarkably good agreement with phenomenology, even though we cannot take the continuum and thermodynamic limits.

  13. Twist-1 Up-Regulation in Carcinoma Correlates to Poor Survival

    Directory of Open Access Journals (Sweden)

    Alimujiang Wushou

    2014-11-01

    Full Text Available Epithelial-to-mesenchymal transition (EMT facilitates tumor metastasis. Twist is a basic helix-loop-helix protein that modulates many target genes through E-box-responsive elements. There are two twist-like proteins, Twist-1 and Twist-2, sharing high structural homology in mammals. Twist-1 was found to be a key factor in the promotion of metastasis of cancer cells, and is known to induce EMT. Twist-1 participation in carcinoma progression and metastasis has been reported in a variety of tumors. However, controversy exists concerning the correlation between Twist-1 and prognostic value with respect to carcinoma. A systematic review and meta-analysis were performed to determine whether the expression of Twist-1 was associated with the prognosis of carcinoma patients. This analysis included 17 studies: four studies evaluated lung cancer, three evaluated head and neck cancer, two evaluated breast cancer, two evaluated esophageal cancer, two evaluated liver cancer and one each evaluated osteosarcoma, bladder, cervical and ovarian cancer. A total of 2006 patients were enrolled in these studies, and the median trial sample size was 118 patients. Twist-1 expression was associated with worse overall survival (OS at both 3 years (hazard ratio “HR” for death = 2.13, 95% CI = 1.86 to 2.45, p < 0.001 and 5 years (HR for death = 2.01, 95% CI = 1.76 to 2.29, p < 0.001. Expression of Twist-1 is associated with worse survival in carcinoma.

  14. Euclidean supersymmetry, twisting and topological sigma models

    International Nuclear Information System (INIS)

    Hull, C.M.; Lindstroem, U.; Santos, L. Melo dos; Zabzine, M.; Unge, R. von

    2008-01-01

    We discuss two dimensional N-extended supersymmetry in Euclidean signature and its R-symmetry. For N = 2, the R-symmetry is SO(2) x SO(1, 1), so that only an A-twist is possible. To formulate a B-twist, or to construct Euclidean N = 2 models with H-flux so that the target geometry is generalised Kahler, it is necessary to work with a complexification of the sigma models. These issues are related to the obstructions to the existence of non-trivial twisted chiral superfields in Euclidean superspace.

  15. Oliver Twist

    NARCIS (Netherlands)

    Dickens, Charles

    2005-01-01

    Oliver Twist is one of Dickens's most popular novels, with many famous film, television and musical adaptations. It is a classic story of good against evil, packed with humour and pathos, drama and suspense, in which the orphaned Oliver is brought up in a harsh workhouse, and then taken in and

  16. Duality and braiding in twisted quantum field theory

    International Nuclear Information System (INIS)

    Riccardi, Mauro; Szabo, Richard J.

    2008-01-01

    We re-examine various issues surrounding the definition of twisted quantum field theories on flat noncommutative spaces. We propose an interpretation based on nonlocal commutative field redefinitions which clarifies previously observed properties such as the formal equivalence of Green's functions in the noncommutative and commutative theories, causality, and the absence of UV/IR mixing. We use these fields to define the functional integral formulation of twisted quantum field theory. We exploit techniques from braided tensor algebra to argue that the twisted Fock space states of these free fields obey conventional statistics. We support our claims with a detailed analysis of the modifications induced in the presence of background magnetic fields, which induces additional twists by magnetic translation operators and alters the effective noncommutative geometry seen by the twisted quantum fields. When two such field theories are dual to one another, we demonstrate that only our braided physical states are covariant under the duality

  17. Twist-2 at seven loops in planar N=4 SYM theory: full result and analytic properties

    Energy Technology Data Exchange (ETDEWEB)

    Marboe, Christian [School of Mathematics, Trinity College Dublin,College Green, Dublin 2 (Ireland); Institut für Mathematik und Institut für Physik, Humboldt-Universität zu Berlin,IRIS Adlershof, Zum Großen Windkanal 6, 12489 Berlin (Germany); Velizhanin, Vitaly [Theoretical Physics Division, NRC “Kurchatov Institute”,Petersburg Nuclear Physics Institute, Orlova Roscha,Gatchina, 188300 St. Petersburg (Russian Federation); Institut für Mathematik und Institut für Physik, Humboldt-Universität zu Berlin,IRIS Adlershof, Zum Großen Windkanal 6, 12489 Berlin (Germany)

    2016-11-04

    The anomalous dimension of twist-2 operators of arbitrary spin in planar N=4 SYM theory is found at seven loops by using the quantum spectral curve to compute values at fixed spin, and reconstructing the general result using the LLL-algorithm together with modular arithmetic. The result of the analytic continuation to negative spin is presented, and its relation with the recently computed correction to the BFKL and double-logarithmic equation is discussed.

  18. Twisted Acceleration-Enlarged Newton-Hooke Hopf Algebras

    International Nuclear Information System (INIS)

    Daszkiewicz, M.

    2010-01-01

    Ten Abelian twist deformations of acceleration-enlarged Newton-Hooke Hopf algebra are considered. The corresponding quantum space-times are derived as well. It is demonstrated that their contraction limit τ → ∞ leads to the new twisted acceleration-enlarged Galilei spaces. (author)

  19. TWIST1 promotes invasion through mesenchymal change in human glioblastoma

    Directory of Open Access Journals (Sweden)

    Wakimoto Hiroaki

    2010-07-01

    Full Text Available Abstract Background Tumor cell invasion into adjacent normal brain is a mesenchymal feature of GBM and a major factor contributing to their dismal outcomes. Therefore, better understandings of mechanisms that promote mesenchymal change in GBM are of great clinical importance to address invasion. We previously showed that the bHLH transcription factor TWIST1 which orchestrates carcinoma metastasis through an epithelial mesenchymal transition (EMT is upregulated in GBM and promotes invasion of the SF767 GBM cell line in vitro. Results To further define TWIST1 functions in GBM we tested the impact of TWIST1 over-expression on invasion in vivo and its impact on gene expression. We found that TWIST1 significantly increased SNB19 and T98G cell line invasion in orthotopic xenotransplants and increased expression of genes in functional categories associated with adhesion, extracellular matrix proteins, cell motility and locomotion, cell migration and actin cytoskeleton organization. Consistent with this TWIST1 reduced cell aggregation, promoted actin cytoskeletal re-organization and enhanced migration and adhesion to fibronectin substrates. Individual genes upregulated by TWIST1 known to promote EMT and/or GBM invasion included SNAI2, MMP2, HGF, FAP and FN1. Distinct from carcinoma EMT, TWIST1 did not generate an E- to N-cadherin "switch" in GBM cell lines. The clinical relevance of putative TWIST target genes SNAI2 and fibroblast activation protein alpha (FAP identified in vitro was confirmed by their highly correlated expression with TWIST1 in 39 human tumors. The potential therapeutic importance of inhibiting TWIST1 was also shown through a decrease in cell invasion in vitro and growth of GBM stem cells. Conclusions Together these studies demonstrated that TWIST1 enhances GBM invasion in concert with mesenchymal change not involving the canonical cadherin switch of carcinoma EMT. Given the recent recognition that mesenchymal change in GBMs is

  20. Correction for the twist and the conical defects of a sagittaly bent crystal

    CERN Document Server

    Ferrer, J L

    1999-01-01

    The symmetrical bending of the focusing crystal of a double X-ray monochromator is a difficult problem. Indeed, the slope due to the curvature is usually three orders of magnitude higher than the accepted slope error (typically, the Darwin width of the crystal). In these conditions, even a low parasitic slope error induced by the bending process may lead to quite a strong intensity decrease. When the bending moment is applied, the main parasitic distortions which may appear are typically the anticlastic curvature, the inhomogeneous sagittal curvature, the conical shape and the twist. On the D2AM beamline at the ESRF, a program called CHKC2 has been developed to correct on-line the latter two distortions: the conical shape and the twist. On this beamline the X-ray beam, which has been collimated by a grazing angle mirror, is monochromatized first by a flat silicon crystal, and then diffracted by the sagittaly curved crystal. A fluorescent screen gives an image of this diffracted beam. The CHKC2 program records...

  1. Renormalization of quark propagator, vertex functions, and twist-2 operators from twisted-mass lattice QCD at Nf=4

    Science.gov (United States)

    Blossier, Benoît.; Brinet, Mariane; Guichon, Pierre; Morénas, Vincent; Pène, Olivier; Rodríguez-Quintero, Jose; Zafeiropoulos, Savvas

    2015-06-01

    We present a precise nonperturbative determination of the renormalization constants in the mass independent RI'-MOM scheme. The lattice implementation uses the Iwasaki gauge action and four degenerate dynamical twisted-mass fermions. The gauge configurations are provided by the ETM Collaboration. Renormalization constants for scalar, pseudoscalar, vector and axial operators, as well as the quark propagator renormalization, are computed at three different values of the lattice spacing, two volumes and several twisted-mass parameters. The method we developed allows for a precise cross-check of the running, thanks to the particular proper treatment of hypercubic artifacts. Results for the twist-2 operator O44 are also presented.

  2. Twisting the N=2 string

    International Nuclear Information System (INIS)

    Ketov, S.V.; Lechtenfeld, O.; Parkes, A.J.

    1993-12-01

    The most general homogeneous monodromy conditions in N= 2 string theory are classified in terms of the conjugacy classes of the global symmetry group U(1, 1) x Z 2 . For classes which generate a discrete subgroup Γ, the corresponding target space backgrounds C 1,1 /Γ include half spaces, complex orbifolds and tori. We propose a generalization of the intercept formula to matrix-valued twists, and find massless physical states in a number of twisted cases. In particular, the sixteen Z 2 -twisted sectors of the N = 2 string are investigated, and the corresponding ground states are identified via bosonization and BRST cohomology. We find enough room for an extended multiplet of 'spacetime' supersymmetry, with the number of supersymmetries being dependent on global 'spacetime' topology. Unfortunately, world-sheet locality for the chiral vertex operators does not permit interactions for the massless 'spacetime' fermions; however possibly, an asymmetric GSO projection could evade this problem. (orig.)

  3. APC-PC Combined Scheme in Gilbert Two State Model: Proposal and Study

    Science.gov (United States)

    Bulo, Yaka; Saring, Yang; Bhunia, Chandan Tilak

    2017-04-01

    In an automatic repeat request (ARQ) scheme, a packet is retransmitted if it gets corrupted due to transmission errors caused by the channel. However, an erroneous packet may contain both erroneous bits and correct bits and hence it may still contain useful information. The receiver may be able to combine this information from multiple erroneous copies to recover the correct packet. Packet combining (PC) is a simple and elegant scheme of error correction in transmitted packet, in which two received copies are XORed to obtain the bit location of erroneous bits. Thereafter, the packet is corrected by bit inversion of bit located as erroneous. Aggressive packet combining (APC) is a logic extension of PC primarily designed for wireless communication with objective of correcting error with low latency. PC offers higher throughput than APC, but PC does not correct double bit errors if occur in same bit location of erroneous copies of the packet. A hybrid technique is proposed to utilize the advantages of both APC and PC while attempting to remove the limitation of both. In the proposed technique, applications of APC-PC on Gilbert two state model has been studied. The simulation results show that the proposed technique offers better throughput than the conventional APC and lesser packet error rate than PC scheme.

  4. Scanning tunneling microscopy and spectroscopy of twisted trilayer graphene

    Science.gov (United States)

    Zuo, Wei-Jie; Qiao, Jia-Bin; Ma, Dong-Lin; Yin, Long-Jing; Sun, Gan; Zhang, Jun-Yang; Guan, Li-Yang; He, Lin

    2018-01-01

    Twist, as a simple and unique degree of freedom, could lead to enormous novel quantum phenomena in bilayer graphene. A small rotation angle introduces low-energy van Hove singularities (VHSs) approaching the Fermi level, which result in unusual correlated states in the bilayer graphene. It is reasonable to expect that the twist could also affect the electronic properties of few-layer graphene dramatically. However, such an issue has remained experimentally elusive. Here, by using scanning tunneling microscopy/spectroscopy (STM/STS), we systematically studied a twisted trilayer graphene (TTG) with two different small twist angles between adjacent layers. Two sets of VHSs, originating from the two twist angles, were observed in the TTG, indicating that the TTG could be simply regarded as a combination of two different twisted bilayers of graphene. By using high-resolution STS, we observed a split of the VHSs and directly imaged the spatial symmetry breaking of electronic states around the VHSs. These results suggest that electron-electron interactions play an important role in affecting the electronic properties of graphene systems with low-energy VHSs.

  5. Twisted boundary states in c=1 coset conformal field theories

    International Nuclear Information System (INIS)

    Ishikawa, Hiroshi; Yamaguchi, Atsushi

    2003-01-01

    We study the mutual consistency of twisted boundary conditions in the coset conformal field theory G/H. We calculate the overlap of the twisted boundary states of G/H with the untwisted ones, and show that the twisted boundary states are consistently defined in the charge-conjugation modular invariant. The overlap of the twisted boundary states is expressed by the branching functions of a twisted affine Lie algebra. As a check of our argument, we study the diagonal coset theory so(2n) 1 +so(2n) 1 /so(2n) 2 , which is equivalent to the orbifold S 1 /Z 2 at a particular radius. We construct the boundary states twisted by the automorphisms of the unextended Dynkin diagram of so(2n), and show their mutual consistency by identifying their counterpart in the orbifold. For the triality of so(8), the twisted states of the coset theory correspond to neither the Neumann nor the Dirichlet boundary states of the orbifold and yield conformal boundary states that preserve only the Virasoro algebra. (author)

  6. Twisted covariant noncommutative self-dual gravity

    International Nuclear Information System (INIS)

    Estrada-Jimenez, S.; Garcia-Compean, H.; Obregon, O.; Ramirez, C.

    2008-01-01

    A twisted covariant formulation of noncommutative self-dual gravity is presented. The formulation for constructing twisted noncommutative Yang-Mills theories is used. It is shown that the noncommutative torsion is solved at any order of the θ expansion in terms of the tetrad and some extra fields of the theory. In the process the first order expansion in θ for the Plebanski action is explicitly obtained.

  7. Soft tissue twisting injuries of the knee

    International Nuclear Information System (INIS)

    Magee, T.; Shapiro, M.

    2001-01-01

    Twisting injuries occur as a result of differential motion of different tissue types in injuries with some rotational force. These injuries are well described in brain injuries but, to our knowledge, have not been described in the musculoskeletal literature. We correlated the clinical examination and MR findings of 20 patients with twisting injuries of the soft tissues around the knee. Design and patients: We prospectively followed the clinical courses of 20 patients with knee injuries who had clinical histories and MR findings to suggest twisting injuries of the subcutaneous tissues. Patients with associated internal derangement of the knee (i.e., meniscal tears, ligamentous or bone injuries) were excluded from this study. MR findings to suggest twisting injuries included linear areas of abnormal dark signal on T1-weighted sequences and abnormal bright signal on T2-weighted or short tau inversion recovery (STIR) sequences and/or signal to suggest hemorrhage within the subcutaneous tissues. These MR criteria were adapted from those established for indirect musculotendinous junction injuries. Results: All 20 patients presented with considerable pain that suggested internal derangement on physical examination by the referring orthopedic surgeons. All presented with injuries associated with rotational force. The patients were placed on a course of protected weight-bearing of the affected extremity for 4 weeks. All patients had pain relief by clinical examination after this period of protected weight-bearing. Twisting injuries of the soft tissues can result in considerable pain that can be confused with internal derangement of the knee on physical examination. Soft tissue twisting injuries need to be recognized on MR examinations as they may be the cause of the patient's pain despite no MR evidence of internal derangement of the knee. The demonstration of soft tissue twisting injuries in a patient with severe knee pain but no documented internal derangement on MR

  8. Reaction mechanism of the acidic hydrolysis of highly twisted amides: Rate acceleration caused by the twist of the amide bond.

    Science.gov (United States)

    Mujika, Jon I; Formoso, Elena; Mercero, Jose M; Lopez, Xabier

    2006-08-03

    We present an ab initio study of the acid hydrolysis of a highly twisted amide and a planar amide analogue. The aim of these studies is to investigate the effect that the twist of the amide bond has on the reaction barriers and mechanism of acid hydrolysis. Concerted and stepwise mechanisms were investigated using density functional theory and polarizable continuum model calculations. Remarkable differences were observed between the mechanism of twisted and planar amide, due mainly to the preference for N-protonation of the former and O-protonation of the latter. In addition, we were also able to determine that the hydrolytic mechanism of the twisted amide will be pH dependent. Thus, there is a preference for a stepwise mechanism with formation of an intermediate in the acid hydrolysis, whereas the neutral hydrolysis undergoes a concerted-type mechanism. There is a nice agreement between the characterized intermediate and available X-ray data and a good agreement with the kinetically estimated rate acceleration of hydrolysis with respect to analogous undistorted amide compounds. This work, along with previous ab initio calculations, describes a complex and rich chemistry for the hydrolysis of highly twisted amides as a function of pH. The theoretical data provided will allow for a better understanding of the available kinetic data of the rate acceleration of amides upon twisting and the relation of the observed rate acceleration with intrinsic differential reactivity upon loss of amide bond resonance.

  9. A twisted generalization of Novikov-Poisson algebras

    OpenAIRE

    Yau, Donald

    2010-01-01

    Hom-Novikov-Poisson algebras, which are twisted generalizations of Novikov-Poisson algebras, are studied. Hom-Novikov-Poisson algebras are shown to be closed under tensor products and several kinds of twistings. Necessary and sufficient conditions are given under which Hom-Novikov-Poisson algebras give rise to Hom-Poisson algebras.

  10. Double-decker phthalocyanine complex: Scanning tunneling microscopy study of film formation and spin properties

    Science.gov (United States)

    Komeda, Tadahiro; Katoh, Keiichi; Yamashita, Masahiro

    2014-05-01

    We review recent studies of double-decker and triple-decker phthalocyanine (Pc) molecules adsorbed on surfaces in terms of the bonding configuration, electronic structure and spin state. The Pc molecule has been studied extensively in surface science. A Pc molecule can contain various metal atoms at the center, and the class of the molecule is called as metal phthalocyanine (MPc). If the center metal has a large radius, like as lanthanoid metals, it becomes difficult to incorporate the metal atom inside of the Pc ring. Pc ligands are placed so as to sandwich the metal atom, where the metal atom is placed out of the Pc plane. The molecule in this configuration is called as a multilayer-decker Pc molecule. After the finding that the double-decker Pc lanthanoid complex shows single-molecule magnet (SMM) behavior, it has attracted a large attention. This is partly due to a rising interest for the ‘molecular spintronics’, in which the freedoms of spin and charge of an electron are applied to the quantum process of information. SMMs represent a class of compounds in which a single molecule behaves as a magnet. The reported blocking temperature, below which a single SMM molecule works as an quantum magnet, has been increasing with the development in the molecular design and synthesis techniques of multiple-decker Pc complex. However, even the bulk properties of these molecules are promising for the use of electronic materials, the films of multi-decker Pc molecules is less studied than those for the MPc molecules. An intriguing structural property is expected for the multi-decker Pc molecules since the Pc planes are linked by metal atoms. This gives an additional degree of freedom to the rotational angle between the two Pc ligands, and they can make a wheel-like symmetric rotation. Due to a simple and well-defined structure of a multi-decker Pc complex, the molecule can be a model molecule for molecular machine studies. The multi-decker Pc molecules can provide

  11. Introduction to twisted conformal fields

    International Nuclear Information System (INIS)

    Kazama, Y.

    1988-01-01

    A pedagogical account is given of the recent developments in the theory of twisted conformal fields. Among other things, the main part of the lecture concerns the construction of the twist-emission vertex operator, which is a generalization of the fermion emission vertex in the superstring theory. Several different forms of the vertex are derived and their mutural relationships are clarified. In this paper, the authors include a brief survey of the history of the fermion emission vertex, as it offers a good perspective in which to appreciate the logical development

  12. On the performance analysis of Savonius rotor with twisted blades

    Energy Technology Data Exchange (ETDEWEB)

    Saha, U.K.; Rajkumar, M. Jaya [Department of Mechanical Engineering, Indian Institute of Technology Guwahati, Guwahati-781 039 (India)

    2006-09-15

    The present investigation is aimed at exploring the feasibility of twisted bladed Savonius rotor for power generation. The twisted blade in a three-bladed rotor system has been tested in a low speed wind tunnel, and its performance has been compared with conventional semicircular blades (with twist angle of 0{sup o}). Performance analysis has been made on the basis of starting characteristics, static torque and rotational speed. Experimental evidence shows the potential of the twisted bladed rotor in terms of smooth running, higher efficiency and self-starting capability as compared to that of the conventional bladed rotor. Further experiments have been conducted in the same setup to optimize the twist angle. (author)

  13. New look at the dynamics of twisted accretion disks

    International Nuclear Information System (INIS)

    Hatchett, S.P.; Begelman, M.C.; Sarazin, C.L.

    1981-01-01

    We reexamine the dynamic response of a thin, accretion disk to twisting torques, guided by the earlier analyses by Bardeen and Petterson. We make several corrections to this earlier work, and present a new version of the twist equations consistent with their physical assumptions. By describing the distortion of the disk in terms Cartesian direction cosines rather than the Euler angles used by the earlier authors, we are able to transform the twist equations from a pair of coupled, nonlinear, partial differential equations to a single, linear, complex one. We write down formulae for the external twisting torques likley to be encountered in astrophysic, and we show that even with these driving torques our twist equation remains linear. We find exact, analytic solutions for steady state structure of a disk subject to Lense-Thirring torques by a nonaligned central Kerr black hole and also for the time-dependent problem of the structure of a slaved disk with its oscillating boundary conditions. Finally, we discuss the stability of disks against twisting modes and show that undriven disks and disks subject to time-independent driving torques are stable

  14. Reversible Twisting of Primary Amides via Ground State N-C(O) Destabilization: Highly Twisted Rotationally Inverted Acyclic Amides.

    Science.gov (United States)

    Meng, Guangrong; Shi, Shicheng; Lalancette, Roger; Szostak, Roman; Szostak, Michal

    2018-01-17

    Since the seminal studies by Pauling in 1930s, planarity has become the defining characteristic of the amide bond. Planarity of amides has central implications for the reactivity and chemical properties of amides of relevance to a range of chemical disciplines. While the vast majority of amides are planar, nonplanarity has a profound effect on the properties of the amide bond, with the most common method to restrict the amide bond relying on the incorporation of the amide function into a rigid cyclic ring system. In a major departure from this concept, here, we report the first class of acyclic twisted amides that can be prepared, reversibly, from common primary amides in a single, operationally trivial step. Di-tert-butoxycarbonylation of the amide nitrogen atom yields twisted amides in which the amide bond exhibits nearly perpendicular twist. Full structural characterization of a range of electronically diverse compounds from this new class of twisted amides is reported. Through reactivity studies we demonstrate unusual properties of the amide bond, wherein selective cleavage of the amide bond can be achieved by a judicious choice of the reaction conditions. Through computational studies we evaluate structural and energetic details pertaining to the amide bond deformation. The ability to selectively twist common primary amides, in a reversible manner, has important implications for the design and application of the amide bond nonplanarity in structural chemistry, biochemistry and organic synthesis.

  15. Modal properties and stability of bend–twist coupled wind turbine blades

    Directory of Open Access Journals (Sweden)

    A. R. Stäblein

    2017-06-01

    Full Text Available Coupling between bending and twist has a significant influence on the aeroelastic response of wind turbine blades. The coupling can arise from the blade geometry (e.g. sweep, prebending, or deflection under load or from the anisotropic properties of the blade material. Bend–twist coupling can be utilized to reduce the fatigue loads of wind turbine blades. In this study the effects of material-based coupling on the aeroelastic modal properties and stability limits of the DTU 10 MW Reference Wind Turbine are investigated. The modal properties are determined by means of eigenvalue analysis around a steady-state equilibrium using the aero-servo-elastic tool HAWCStab2 which has been extended by a beam element that allows for fully coupled cross-sectional properties. Bend–twist coupling is introduced in the cross-sectional stiffness matrix by means of coupling coefficients that introduce twist for flapwise (flap–twist coupling or edgewise (edge–twist coupling bending. Edge–twist coupling can increase or decrease the damping of the edgewise mode relative to the reference blade, depending on the operational condition of the turbine. Edge–twist to feather coupling for edgewise deflection towards the leading edge reduces the inflow speed at which the blade becomes unstable. Flap–twist to feather coupling for flapwise deflections towards the suction side increase the frequency and reduce damping of the flapwise mode. Flap–twist to stall reduces frequency and increases damping. The reduction of blade root flapwise and tower bottom fore–aft moments due to variations in mean wind speed of a flap–twist to feather blade are confirmed by frequency response functions.

  16. Twisted sigma-model solitons on the quantum projective line

    Science.gov (United States)

    Landi, Giovanni

    2018-04-01

    On the configuration space of projections in a noncommutative algebra, and for an automorphism of the algebra, we use a twisted Hochschild cocycle for an action functional and a twisted cyclic cocycle for a topological term. The latter is Hochschild-cohomologous to the former and positivity in twisted Hochschild cohomology results into a lower bound for the action functional. While the equations for the critical points are rather involved, the use of the positivity and the bound by the topological term lead to self-duality equations (thus yielding twisted noncommutative sigma-model solitons, or instantons). We present explicit nontrivial solutions on the quantum projective line.

  17. Precision Measurement of the Neutron Twist-3 Matrix Element dn2: Probing Color Forces

    Energy Technology Data Exchange (ETDEWEB)

    Posik, Matthew; Flay, David; Parno, Diana; Allada, Kalyan; Armstrong, Whitney; Averett, Todd; Benmokhtar, Fatiha; Bertozzi, William; Camsonne, Alexandre; Canan, Mustafa; Cates, Gordon; Chen, Chunhua; Chen, Jian-Ping; Choi, Seonho; Chudakov, Eugene; Cusanno, Francesco; Dalton, Mark; Deconinck, Wouter; De Jager, Cornelis; Deng, Xiaoyan; Deur, Alexandre; Dutta, Chiranjib; El Fassi, Lamiaa; Franklin, Gregg; Friend, Megan; Gao, Haiyan; Garibaldi, Franco; Gilad, Shalev; Gilman, Ronald; Glamazdin, Oleksandr; Golge, Serkan; Gomez, Javier; Guo, Lei; Hansen, Jens-Ole; Higinbotham, Douglas; Holmstrom, Timothy; Huang, J; Hyde, Charles; Ibrahim Abdalla, Hassan; Jiang, Xiaodong; Jin, Ge; Katich, Joseph; Kelleher, Aidan; Kolarkar, Ameya; Korsch, Wolfgang; Kumbartzki, Gerfried; LeRose, John; Lindgren, Richard; Liyanage, Nilanga; Long, Elena; Lukhanin, Oleksandr; Mamyan, Vahe; McNulty, Dustin; Meziani, Zein-Eddine; Michaels, Robert; Mihovilovic, Miha; Moffit, Bryan; Muangma, Navaphon; Nanda, Sirish; Narayan, Amrendra; Nelyubin, Vladimir; Norum, Blaine; Nuruzzaman, nfn; Oh, Yongseok; Peng, Jen-chieh; Qian, Xin; Qiang, Yi; Rakhman, Abdurahim; Riordan, Seamus; Saha, Arunava; Sawatzky, Bradley; Hashemi Shabestari, Mitra; Shahinyan, Albert; Sirca, Simon; Solvignon-Slifer, Patricia; Subedi, Ramesh; Sulkosky, Vincent; Tobias, William; Troth, Wolfgang; Wang, Diancheng; Wang, Y; Wojtsekhowski, Bogdan; Yan, X; Yao, Huan; Ye, Yunxiu; Ye, Zhihong; Yuan, Lulin; Zhan, X; Zhang, Y; Zhang, Y -W; Zhao, Bo; Zheng, Xiaochao

    2014-07-01

    Double-spin asymmetries and absolute cross sections were measured at large Bjorken x (0.25 lte x lte 0.90), in both the deep-inelastic and resonance regions, by scattering longitudinally polarized electrons at beam energies of 4.7 and 5.9 GeV from a transversely and longitudinally polarized 3He target. In this dedicated experiment, the spin structure function g2 on 3He was determined with precision at large x, and the neutron twist-three matrix element dn2 was measured at ?Q2? of 3.21 and 4.32 GeV2/c2, with an absolute precision of about 10?5. Our results are found to be in agreement with lattice QCD calculations and resolve the disagreement found with previous data at ?Q2?= 5 GeV2/c2. Combining dn2 and a newly extracted twist-four matrix element, fn2, the average neutron color electric and magnetic forces were extracted and found to be of opposite sign and about 60 MeV/fm in magnitude.

  18. A higher twist correction to heavy quark production

    International Nuclear Information System (INIS)

    Brodsky, S.J.; Gunion, J.F.; Soper, D.E.

    1987-06-01

    The leading twist prediction for heavy quark production and a model for a higher twist correction that may be important for charm production was discussed. The correction arises from the interaction of the charm quark with spectator quarks

  19. The Twist Tensor Nuclear Norm for Video Completion.

    Science.gov (United States)

    Hu, Wenrui; Tao, Dacheng; Zhang, Wensheng; Xie, Yuan; Yang, Yehui

    2017-12-01

    In this paper, we propose a new low-rank tensor model based on the circulant algebra, namely, twist tensor nuclear norm (t-TNN). The twist tensor denotes a three-way tensor representation to laterally store 2-D data slices in order. On one hand, t-TNN convexly relaxes the tensor multirank of the twist tensor in the Fourier domain, which allows an efficient computation using fast Fourier transform. On the other, t-TNN is equal to the nuclear norm of block circulant matricization of the twist tensor in the original domain, which extends the traditional matrix nuclear norm in a block circulant way. We test the t-TNN model on a video completion application that aims to fill missing values and the experiment results validate its effectiveness, especially when dealing with video recorded by a nonstationary panning camera. The block circulant matricization of the twist tensor can be transformed into a circulant block representation with nuclear norm invariance. This representation, after transformation, exploits the horizontal translation relationship between the frames in a video, and endows the t-TNN model with a more powerful ability to reconstruct panning videos than the existing state-of-the-art low-rank models.

  20. Development of double chain phosphatidylcholine functionalized polymeric monoliths for immobilized artificial membrane chromatography.

    Science.gov (United States)

    Wang, Qiqin; Peng, Kun; Chen, Weijia; Cao, Zhen; Zhu, Peijie; Zhao, Yumei; Wang, Yuqiang; Zhou, Haibo; Jiang, Zhengjin

    2017-01-06

    This study described a simple synthetic methodology for preparing biomembrane mimicking monolithic column. The suggested approach not only simplifies the preparation procedure but also improves the stability of double chain phosphatidylcholine (PC) functionalized monolithic column. The physicochemical properties of the optimized monolithic column were characterized by scanning electron microscopy, energy-dispersive X-ray spectrometry, and nano-LC. Satisfactory column permeability, efficiency, stability and reproducibility were obtained on this double chain PC functionalized monolithic column. It is worth noting that the resulting polymeric monolith exhibits great potential as a useful alternative of commercial immobilized artificial membrane (IAM) columns for in vitro predication of drug-membrane interactions. Furthermore, the comparative study of both double chain and single chain PC functionalized monoliths indicates that the presence or absence of glycerol backbone and the number of acyl chains are not decisive for the predictive ability of IAM monoliths on drug-membrane interactions. This novel PC functionalized monolithic column also exhibited good selectivity for a protein mixture and a set of pharmaceutical compounds. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. The upstream enhancer elements of the G6PC promoter are critical for optimal G6PC expression in murine glycogen storage disease type Ia.

    Science.gov (United States)

    Lee, Young Mok; Pan, Chi-Jiunn; Koeberl, Dwight D; Mansfield, Brian C; Chou, Janice Y

    2013-11-01

    Glycogen storage disease type-Ia (GSD-Ia) patients deficient in glucose-6-phosphatase-α (G6Pase-α or G6PC) manifest impaired glucose homeostasis characterized by fasting hypoglycemia, growth retardation, hepatomegaly, nephromegaly, hyperlipidemia, hyperuricemia, and lactic acidemia. Two efficacious recombinant adeno-associated virus pseudotype 2/8 (rAAV8) vectors expressing human G6Pase-α have been independently developed. One is a single-stranded vector containing a 2864-bp of the G6PC promoter/enhancer (rAAV8-GPE) and the other is a double-stranded vector containing a shorter 382-bp minimal G6PC promoter/enhancer (rAAV8-miGPE). To identify the best construct, a direct comparison of the rAAV8-GPE and the rAAV8-miGPE vectors was initiated to determine the best vector to take forward into clinical trials. We show that the rAAV8-GPE vector directed significantly higher levels of hepatic G6Pase-α expression, achieved greater reduction in hepatic glycogen accumulation, and led to a better toleration of fasting in GSD-Ia mice than the rAAV8-miGPE vector. Our results indicated that additional control elements in the rAAV8-GPE vector outweigh the gains from the double-stranded rAAV8-miGPE transduction efficiency, and that the rAAV8-GPE vector is the current choice for clinical translation in human GSD-Ia. © 2013.

  2. Level-rank duality of untwisted and twisted D-branes

    International Nuclear Information System (INIS)

    Naculich, Stephen G.; Schnitzer, Howard J.

    2006-01-01

    Level-rank duality of untwisted and twisted D-branes of WZW models is explored. We derive the relation between D0-brane charges of level-rank dual untwisted D-branes of su-bar (N) K and sp-bar (n) k , and of level-rank dual twisted D-branes of su-bar (2n+1) 2k+1 . The analysis of level-rank duality of twisted D-branes of su-bar (2n+1) 2k+1 is facilitated by their close relation to untwisted D-branes of sp-bar (n) k . We also demonstrate level-rank duality of the spectrum of an open string stretched between untwisted or twisted D-branes in each of these cases

  3. Bound states on the lattice with partially twisted boundary conditions

    International Nuclear Information System (INIS)

    Agadjanov, D.; Guo, F.-K.; Ríos, G.; Rusetsky, A.

    2015-01-01

    We propose a method to study the nature of exotic hadrons by determining the wave function renormalization constant Z from lattice simulations. It is shown that, instead of studying the volume-dependence of the spectrum, one may investigate the dependence of the spectrum on the twisting angle, imposing twisted boundary conditions on the fermion fields on the lattice. In certain cases, e.g., the case of the DK bound state which is addressed in detail, it is demonstrated that the partial twisting is equivalent to the full twisting up to exponentially small corrections.

  4. OAM mode converter in twisted fibers

    DEFF Research Database (Denmark)

    Usuga Castaneda, Mario A.; Beltran-Mejia, Felipe; Cordeiro, Cristiano

    2014-01-01

    We analyze the case of an OAM mode converter based on a twisted fiber, through finite element simulations where we exploit an equivalence between geometric and material transformations. The obtained converter has potential applications in MDM. © 2014 OSA.......We analyze the case of an OAM mode converter based on a twisted fiber, through finite element simulations where we exploit an equivalence between geometric and material transformations. The obtained converter has potential applications in MDM. © 2014 OSA....

  5. Twisting perturbed parafermions

    Directory of Open Access Journals (Sweden)

    A.V. Belitsky

    2017-07-01

    Full Text Available The near-collinear expansion of scattering amplitudes in maximally supersymmetric Yang–Mills theory at strong coupling is governed by the dynamics of stings propagating on the five sphere. The pentagon transitions in the operator product expansion which systematize the series get reformulated in terms of matrix elements of branch-point twist operators in the two-dimensional O(6 nonlinear sigma model. The facts that the latter is an asymptotically free field theory and that there exists no local realization of twist fields prevents one from explicit calculation of their scaling dimensions and operator product expansion coefficients. This complication is bypassed making use of the equivalence of the sigma model to the infinite-level limit of WZNW models perturbed by current–current interactions, such that one can use conformal symmetry and conformal perturbation theory for systematic calculations. Presently, to set up the formalism, we consider the O(3 sigma model which is reformulated as perturbed parafermions.

  6. Twisted Vanes Would Enhance Fuel/Air Mixing In Turbines

    Science.gov (United States)

    Nguyen, H. Lee; Micklow, Gerald J.; Dogra, Anju S.

    1994-01-01

    Computations of flow show performance of high-shear airblast fuel injector in gas-turbine engine enhanced by use of appropriately proportioned twisted (instead of flat) dome swirl vanes. Resultant more nearly uniform fuel/air mixture burns more efficiently, emitting smaller amounts of nitrogen oxides. Twisted-vane high-shear airblast injectors also incorporated into paint sprayers, providing advantages of low pressure drop characteristic of airblast injectors in general and finer atomization of advanced twisted-blade design.

  7. Phosphorylation of basic helix-loop-helix transcription factor Twist in development and disease.

    Science.gov (United States)

    Xue, Gongda; Hemmings, Brian A

    2012-02-01

    The transcription factor Twist plays vital roles during embryonic development through regulating/controlling cell migration. However, postnatally, in normal physiological settings, Twist is either not expressed or inactivated. Increasing evidence shows a strong correlation between Twist reactivation and both cancer progression and malignancy, where the transcriptional activities of Twist support cancer cells to disseminate from primary tumours and subsequently establish a secondary tumour growth in distant organs. However, it is largely unclear how this signalling programme is reactivated or what signalling pathways regulate its activity. The present review discusses recent advances in Twist regulation and activity, with a focus on phosphorylation-dependent Twist activity, potential upstream kinases and the contribution of these factors in transducing biological signals from upstream signalling complexes. The recent advances in these areas have shed new light on how phosphorylation-dependent regulation of the Twist proteins promotes or suppresses Twist activity, leading to differential regulation of Twist transcriptional targets and thereby influencing cell fate.

  8. Further Generalisations of Twisted Gabidulin Codes

    DEFF Research Database (Denmark)

    Puchinger, Sven; Rosenkilde, Johan Sebastian Heesemann; Sheekey, John

    2017-01-01

    We present a new family of maximum rank distance (MRD) codes. The new class contains codes that are neither equivalent to a generalised Gabidulin nor to a twisted Gabidulin code, the only two known general constructions of linear MRD codes.......We present a new family of maximum rank distance (MRD) codes. The new class contains codes that are neither equivalent to a generalised Gabidulin nor to a twisted Gabidulin code, the only two known general constructions of linear MRD codes....

  9. 76 FR 5467 - Airworthiness Directives; Pilatus Aircraft Ltd. Models PC-6, PC-6-H1, PC-6-H2, PC-6/350, PC-6/350...

    Science.gov (United States)

    2011-02-01

    ...;Prices of new books are listed in the first FEDERAL REGISTER issue of each #0;week. #0; #0; #0; #0;#0..., Fairchild Heli Porter PC-6 airplanes, or Fairchild-Hiller Corporation PC-6 airplanes. Discussion Section... [[Page 5469

  10. Geometry of the toroidal N-helix: optimal-packing and zero-twist

    DEFF Research Database (Denmark)

    Olsen, Kasper; Bohr, Jakob

    2012-01-01

    Two important geometrical properties of N-helix structures are influenced by bending. One is maximizing the volume fraction, which is called optimal-packing, and the other is having a vanishing strain-twist coupling, which is called zero-twist. Zero-twist helices rotate neither in one nor...... helix. General N-helices are discussed, as well as zero-twist helices for N > 1. The derived geometrical restrictions are gradually modified by changing the aspect ratio of the torus....

  11. A method to estimate the necessary twist pitch in multi-filamentary superconductors

    International Nuclear Information System (INIS)

    Lindau, S; Magnusson, N; Taxt, H

    2014-01-01

    Twisting of multi-filamentary superconductors is an important step in the development of wires with AC losses at an acceptable level for AC applications. The necessary twist pitch depends on wire architecture, critical current density, matrix material, and external factors such as temperature, frequency and applied magnetic field. The development of an AC optimized MgB 2 superconductor would be facilitated by a fast method to set the requirements for the twist pitch. A problem often encountered when comparing wires with different twist pitches is the degradation in critical current occurring at small twist pitches due to mechanical deformation. In this work we propose to use a non-twisted conductor to estimate the influence of twisting on the AC losses. A long superconductor is cut into smaller lengths, each simulating one third of the twist pitch, and the AC losses due to applied magnetic fields are compared between samples of different lengths. With this method, the effect of reducing the size of the loop of the coupling currents is studied without changing the superconducting parameters. AC loss measurement results are presented for a round titanium matrix MgB 2 wire with simulated twist pitches between 9 mm and 87 mm.

  12. New twist on artificial muscles.

    Science.gov (United States)

    Haines, Carter S; Li, Na; Spinks, Geoffrey M; Aliev, Ali E; Di, Jiangtao; Baughman, Ray H

    2016-10-18

    Lightweight artificial muscle fibers that can match the large tensile stroke of natural muscles have been elusive. In particular, low stroke, limited cycle life, and inefficient energy conversion have combined with high cost and hysteretic performance to restrict practical use. In recent years, a new class of artificial muscles, based on highly twisted fibers, has emerged that can deliver more than 2,000 J/kg of specific work during muscle contraction, compared with just 40 J/kg for natural muscle. Thermally actuated muscles made from ordinary polymer fibers can deliver long-life, hysteresis-free tensile strokes of more than 30% and torsional actuation capable of spinning a paddle at speeds of more than 100,000 rpm. In this perspective, we explore the mechanisms and potential applications of present twisted fiber muscles and the future opportunities and challenges for developing twisted muscles having improved cycle rates, efficiencies, and functionality. We also demonstrate artificial muscle sewing threads and textiles and coiled structures that exhibit nearly unlimited actuation strokes. In addition to robotics and prosthetics, future applications include smart textiles that change breathability in response to temperature and moisture and window shutters that automatically open and close to conserve energy.

  13. Fabrication of wrist-like SMA-based actuator by double smart soft composite casting

    Science.gov (United States)

    Rodrigue, Hugo; Wei, Wang; Bhandari, Binayak; Ahn, Sung-Hoon

    2015-12-01

    A new manufacturing method for smart soft composite (SSC) actuators that consists of double casting a SSC actuator to produce an actuator with non-linear shape memory alloy (SMA) wire positioning is proposed. This method is used to manufacture a tube-shaped SSC actuator in which the SMA wires follow the curvature of the tube and is capable of pure-twisting deformations while sustaining a cantilever load. The concept is tested by measuring the maximum twisting angle and a simple control method is proposed to control the twisting angle of the actuator. Then, a soft robotic wrist with a length of 18 cm is built, its load-carrying capability is tested by measuring the cantilever force required for deforming the actuator, and its load-carrying capability during actuation is tested by loading one end with different objects and actuating the actuator. This wrist actuator shows good repeatability, is capable of twisting deformations up to 25° while holding objects weighing 100 g, and can sustain loads above 2 N without undergoing buckling.

  14. Fabrication of wrist-like SMA-based actuator by double smart soft composite casting

    International Nuclear Information System (INIS)

    Rodrigue, Hugo; Wei, Wang; Bhandari, Binayak; Ahn, Sung-Hoon

    2015-01-01

    A new manufacturing method for smart soft composite (SSC) actuators that consists of double casting a SSC actuator to produce an actuator with non-linear shape memory alloy (SMA) wire positioning is proposed. This method is used to manufacture a tube-shaped SSC actuator in which the SMA wires follow the curvature of the tube and is capable of pure-twisting deformations while sustaining a cantilever load. The concept is tested by measuring the maximum twisting angle and a simple control method is proposed to control the twisting angle of the actuator. Then, a soft robotic wrist with a length of 18 cm is built, its load-carrying capability is tested by measuring the cantilever force required for deforming the actuator, and its load-carrying capability during actuation is tested by loading one end with different objects and actuating the actuator. This wrist actuator shows good repeatability, is capable of twisting deformations up to 25° while holding objects weighing 100 g, and can sustain loads above 2 N without undergoing buckling. (paper)

  15. Electrically Controllable Magnetism in Twisted Bilayer Graphene.

    Science.gov (United States)

    Gonzalez-Arraga, Luis A; Lado, J L; Guinea, Francisco; San-Jose, Pablo

    2017-09-08

    Twisted graphene bilayers develop highly localized states around AA-stacked regions for small twist angles. We show that interaction effects may induce either an antiferromagnetic or a ferromagnetic (FM) polarization of said regions, depending on the electrical bias between layers. Remarkably, FM-polarized AA regions under bias develop spiral magnetic ordering, with a relative 120° misalignment between neighboring regions due to a frustrated antiferromagnetic exchange. This remarkable spiral magnetism emerges naturally without the need of spin-orbit coupling, and competes with the more conventional lattice-antiferromagnetic instability, which interestingly develops at smaller bias under weaker interactions than in monolayer graphene, due to Fermi velocity suppression. This rich and electrically controllable magnetism could turn twisted bilayer graphene into an ideal system to study frustrated magnetism in two dimensions.

  16. Bend-twist coupling potential of wind turbine blades

    DEFF Research Database (Denmark)

    Fedorov, Vladimir; Berggreen, Christian

    2014-01-01

    -twist coupling magnitude of up to 0.2 is feasible to achieve in the baseline blade structure made of glass-fiber reinforced plastics. Further, by substituting the glass-fibers with carbon-fibers the coupling effect can be increased to 0.4. Additionally, the effect of introduction of bend-twist coupling...

  17. Exergy analysis of a combined vapor power cycle and boiler flue gas driven double effect water–LiBr absorption refrigeration system

    International Nuclear Information System (INIS)

    Talukdar, K.; Gogoi, T.K.

    2016-01-01

    Highlights: • A combined vapor power and double effect water–LiBr absorption refrigeration system is proposed. • The flue gas of the power cycle boiler is the heat source for the double effect refrigeration system. • Energy and exergy analyses are performed to evaluate performance of the combined system. • Effect of high pressure generator temperature on combined system performance is highlighted. • Comparison is provided with a single effect absorption system integrated combined system. - Abstract: A combined vapor power cycle (PC) and double effect water–LiBr absorption refrigeration system (ARS) is proposed in this study. The boiler leaving flue gas of the PC is the heat source for the high pressure generator (HPG) of the double effect ARS. Exergy analysis of the proposed system is performed to show the performance variation of both the topping PC and the bottoming ARS with changing HPG temperature from 120 °C to 150 °C. Further the performance of double effect ARS integrated combined power and cooling system is compared with a similar system integrated with a single effect ARS. HPG temperature of the double effect ARS and generator temperature of the single effect ARS are considered as 120 °C and 80 °C respectively. Results show that the power and efficiency of the topping PC decreases with HPG temperature due to reduction in steam generation rate in the boiler. COP and exergy efficiency of the double effect ARS also reduces with increasing HPG temperature. The irreversible losses in the PC components decrease while the total irreversibility of the combined power and cooling system increases with HPG temperature due to increase in exergy loss with the HPG leaving flue gas and irreversibility of the ARS components. PC performance does not vary much due to replacement of the double effect ARS with the single effect ARS, however higher COP and exergy efficiency of the double effect system are achieved with much lower irreversible losses in the

  18. Prostate carcinoma (PC) - an organ-related specific pathological neoplasm

    International Nuclear Information System (INIS)

    Massmann, J.; Funk, A.; Altwein, J.; Praetorius, M.

    2003-01-01

    The organ- and tumour-related specific characteristics of prostate carcinoma (PC) are presented in an overview under various aspects. It is the key for understanding pathological changes, including PC, to consider the subdivision of the prostate into anatomically and functionally distinguishable zones, especially the transitional zone (TZ) and the peripheral zone (PZ). The pseudoneoplastic hyperplasia of the TZ, combined with inflammatory consequences and age-related changes, forms a differential diagnostic challenge to both clinico-radiological diagnosis and macroscopic and microscopic examination. High-degree prostatic intra-epithelial neoplasia (PIN III) and atypical adenomatous hyperplasia (AAH) are presented as precursor lesions of PC with varying significance and assessment. Moreover, there are discussed the following characteristic features of PC: localisation types, focality, volume, progression, double-graduation according to Gleason, tumour stage, and prognosis. The most important prognosis factors of PC (category I) include the categories of the TNM system, such as stage, surgical marginal situation, degree and also the preoperative PSA level as a (poor) substitute for the tumour volume. Potential prognosis parameters (category II) show the tumour volume and the DNS ploidy, while there continues to exist a large number of non-established parameters (category III). The prognostic validity of the pathological examinations depends, on the one hand, on the tissue extent (needle biopsy, transurethral resection (TURP), so-called simple prostatectomy, radical prostatectomy (RPE)) and the prostate zones covered. On the other hand, the prognostic certainty also depends on the tumour-adequate macroscopic and microscopic assessment of an RPE that can only be a partial or complete handling in transversal large-area sections. (orig.) [de

  19. Nonlinear physics of twisted magnetic field lines

    International Nuclear Information System (INIS)

    Yoshida, Zensho

    1998-01-01

    Twisted magnetic field lines appear commonly in many different plasma systems, such as magnetic ropes created through interactions between the magnetosphere and the solar wind, magnetic clouds in the solar wind, solar corona, galactic jets, accretion discs, as well as fusion plasma devices. In this paper, we study the topological characterization of twisted magnetic fields, nonlinear effect induced by the Lorentz back reaction, length-scale bounds, and statistical distributions. (author)

  20. Observations on discretization errors in twisted-mass lattice QCD

    International Nuclear Information System (INIS)

    Sharpe, Stephen R.

    2005-01-01

    I make a number of observations concerning discretization errors in twisted-mass lattice QCD that can be deduced by applying chiral perturbation theory including lattice artifacts. (1) The line along which the partially conserved axial current quark mass vanishes in the untwisted-mass-twisted-mass plane makes an angle to the twisted-mass axis which is a direct measure of O(a) terms in the chiral Lagrangian, and is found numerically to be large; (2) Numerical results for pionic quantities in the mass plane show the qualitative properties predicted by chiral perturbation theory, in particular, an asymmetry in slopes between positive and negative untwisted quark masses; (3) By extending the description of the 'Aoki regime' (where m q ∼a 2 Λ QCD 3 ) to next-to-leading order in chiral perturbation theory I show how the phase-transition lines and lines of maximal twist (using different definitions) extend into this region, and give predictions for the functional form of pionic quantities; (4) I argue that the recent claim that lattice artifacts at maximal twist have apparent infrared singularities in the chiral limit results from expanding about the incorrect vacuum state. Shifting to the correct vacuum (as can be done using chiral perturbation theory) the apparent singularities are summed into nonsingular, and furthermore predicted, forms. I further argue that there is no breakdown in the Symanzik expansion in powers of lattice spacing, and no barrier to simulating at maximal twist in the Aoki regime

  1. Higher-twist correlations in polarized hadrons

    International Nuclear Information System (INIS)

    Tangerman, R.D.

    1996-01-01

    In this thesis we studied the response of polarized hadrons to several high-energy probes, working in the framework of the field theoretic model. Emphasis is laid upon higher-twist effects such as quark transverse momentum. The inclusive DIS process is very well suited to study QCD. From general principles we were able to derive four positivity constraints on the structure functions without invoking the helicity formalism. The on-shell quark model is used to illustrate these constraints. Subseqeuently, we concentrated on the higher-twist structure function g 2 (x,Q 2 ). (orig./HSI)

  2. Transcription factors zeb1, twist and snai1 in breast carcinoma

    International Nuclear Information System (INIS)

    Soini, Ylermi; Tuhkanen, Hanna; Sironen, Reijo; Virtanen, Ismo; Kataja, Vesa; Auvinen, Päivi; Mannermaa, Arto; Kosma, Veli-Matti

    2011-01-01

    Epitheliomesenchymal transition (EMT) is the process where cancer cells attain fibroblastic features and are thus able to invade neighboring tissues. Transcriptional factors zeb1, snai1 and twist regulate EMT. We used immunohistochemistry to investigate the expression of zeb1, twist and snai1 in tumor and stromal compartments by in a large set of breast carcinomas. The results were compared with estrogen and progesterone receptor status, HER2 amplification, grade, histology, TNM status and survival of the patients. Nuclear expression for twist was seen in the epithelial tumor cell compartment in 3.6% and for snai1 in 3.1% of the cases while zeb1 was not detected at all in these areas. In contrast, the tumor stromal compartment showed nuclear zeb1 and twist expression in 75% and 52.4% of the cases, respectively. Although rare, nuclear expression of twist in the epithelial tumor cell compartment was associated with a poor outcome of the patients (p = 0.054 log rank, p = 0.013, Breslow, p = 0.025 Tarone-Ware). Expression of snai1, or expression of zeb1 or twist in the stromal compartment did not have any prognostic significance. Furthermore, none of these factors associated with the size of the tumors, nor with the presence of axillary or distant metastases. Expression of zeb1 and twist in the stromal compartment was positively associated with a positive estrogen or progesterone receptor status of the tumors. Stromal zeb1 expression was significantly lower in ductal in situ carcinomas than in invasive carcinomas (p = 0.020). Medullary carcinomas (p = 0.017) and mucinous carcinomas (p = 0.009) had a lower stromal expression of zeb1 than ductal carcinomas. Stromal twist expression was also lower in mucinous (p = 0.017) than in ductal carcinomas. Expression of transcriptional factors zeb1 and twist mainly occur in the stromal compartment of breast carcinomas, possibly representing two populations of cells; EMT transformed neoplastic cells and stromal fibroblastic cells

  3. Conformal invariance and pion wave functions of nonleading twist

    International Nuclear Information System (INIS)

    Braun, V.M.; Filyanov, I.E.

    1989-01-01

    The restrictions are studied for the general structure of pion wave functions of twist 3 and twist 4 imposed by the conformal symmetry and the equations of motion. A systematic expansion of wave functions in the conformal spin is built and the first order corrections to asymptotic formulae are calculated by the QCD sum rule method. In particular, we have found a multiplicatively renormalizable contribution into the two-particle wave function of twist 4 which cannot be expanded in a finite set of Gegenbauer polynomials. 19 refs.; 5 figs

  4. Enhancement of turbulent flow heat transfer in a tube with modified twisted tapes

    Energy Technology Data Exchange (ETDEWEB)

    Lei, Y.G.; Zhao, C.H.; Song, C.F. [College of Environmental Science and Engineering, Taiyuan University of Technology, Taiyuan (China)

    2012-12-15

    Numerical simulations were performed to study the fluid flow and heat transfer in a tube with staggered twisted tapes with central holes. In the range of Reynolds numbers between 6000 and 28 000, the modified twisted tapes increased the Nusselt number by 76.2 {proportional_to} 149.7 % and the friction factor by 380.2 {proportional_to} 443.8 % compared to the smooth tube. Compared to the typical twisted tapes, the modified twisted tapes produced an acceleration flow through the triangle regions leading to the enhancement of heat transfer, and the holes in the modified tapes reduced the severe pressure loss. It was found that the modified twisted tapes decreased the friction factor by 8.0 {proportional_to} 16.1 % and enhanced the heat transfer by 34.1 {proportional_to} 46.8 % in comparison with the typical tapes. These results indicated that the performance ratio values of the tube with modified twisted tapes were higher than 1.0 in the range of Reynolds numbers studied. The computed performance ratios of the tube with modified twisted tapes were much higher than those of the tube with typical twisted tapes. This means that the integrated performance of the tube with staggered twisted tapes with central holes is superior to that of the tube with typical twisted tapes. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  5. Gauging the twisted Poincare symmetry as a noncommutative theory of gravitation

    International Nuclear Information System (INIS)

    Chaichian, M.; Tureanu, A.; Oksanen, M.; Zet, G.

    2009-01-01

    Einstein's theory of general relativity was formulated as a gauge theory of Lorentz symmetry by Utiyama in 1956, while the Einstein-Cartan gravitational theory was formulated by Kibble in 1961 as the gauge theory of Poincare transformations. In this framework, we propose a formulation of the gravitational theory on canonical noncommutative space-time by covariantly gauging the twisted Poincare symmetry, in order to fulfil the requirement of covariance under the general coordinate transformations, an essential ingredient of the theory of general relativity. It appears that the twisted Poincare symmetry cannot be gauged by generalizing the Abelian twist to a covariant non-Abelian twist, nor by introducing a more general covariant twist element. The advantages of such a formulation as well as the related problems are discussed and possible ways out are outlined.

  6. Iterative methods for overlap and twisted mass fermions

    International Nuclear Information System (INIS)

    Chiarappa, T.; Jansen, K.; Shindler, A.; Wetzorke, I.; Scorzato, L.; Urbach, C.; Wenger, U.

    2006-09-01

    We present a comparison of a number of iterative solvers of linear systems of equations for obtaining the fermion propagator in lattice QCD. In particular, we consider chirally invariant overlap and chirally improved Wilson (maximally) twisted mass fermions. The comparison of both formulations of lattice QCD is performed at four fixed values of the pion mass between 230 MeV and 720 MeV. For overlap fermions we address adaptive precision and low mode preconditioning while for twisted mass fermions we discuss even/odd preconditioning. Taking the best available algorithms in each case we find that calculations with the overlap operator are by a factor of 30-120 more expensive than with the twisted mass operator. (orig.)

  7. Iterative methods for overlap and twisted mass fermions

    Energy Technology Data Exchange (ETDEWEB)

    Chiarappa, T. [Univ. di Milano Bicocca (Italy); Jansen, K.; Shindler, A.; Wetzorke, I. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Nagai, K.I. [Wuppertal Univ. (Gesamthochschule) (Germany). Fachbereich Physik; Papinutto, M. [INFN Sezione di Roma Tre, Rome (Italy); Scorzato, L. [European Centre for Theoretical Studies in Nuclear Physics and Related Areas (ECT), Villazzano (Italy); Urbach, C. [Liverpool Univ. (United Kingdom). Dept. of Mathematical Sciences; Wenger, U. [ETH Zuerich (Switzerland). Inst. fuer Theoretische Physik

    2006-09-15

    We present a comparison of a number of iterative solvers of linear systems of equations for obtaining the fermion propagator in lattice QCD. In particular, we consider chirally invariant overlap and chirally improved Wilson (maximally) twisted mass fermions. The comparison of both formulations of lattice QCD is performed at four fixed values of the pion mass between 230 MeV and 720 MeV. For overlap fermions we address adaptive precision and low mode preconditioning while for twisted mass fermions we discuss even/odd preconditioning. Taking the best available algorithms in each case we find that calculations with the overlap operator are by a factor of 30-120 more expensive than with the twisted mass operator. (orig.)

  8. Template preparation of twisted nanoparticles of mesoporous silica

    Institute of Scientific and Technical Information of China (English)

    Kui Niu; Zhongbin Ni; Chengwu Fu; Tatsuo Kaneko; Mingqing Chen

    2011-01-01

    Optical isomers of N-lauroyl-L-(or-D-) alanine sodium salt {C12-L-(or-D-)AlaS} surfactants were used for the preparation of mesoporous silica nanoparticles with a twisted hexagonal rod-like morphology. Thermogravimetric analysis (TGA) was used to determine the temperature for template removal. Circular dichroism (CD) spectra of the surfactant solution with various compositions illustrated the formation and supramolecular assembly of protein-like molecular architecture leading to formation of twisted nanoparticles. Scanning electron microscopy (SEM),high-resolution transmission electron microscopy (HRTEM)and X-ray powder diffraction (XRD) patterns of these as-synthesized mesoporous silica confirmed that the twisted morphology of these nanoparticles was closely related to the supramolecular-assembled complex of amino acid surfactants.

  9. Correlation Between Expression of Twist and Podoplanin in Ductal Breast Carcinoma.

    Science.gov (United States)

    Grzegrzolka, Jedrzej; Wojtyra, Patrycja; Biala, Martyna; Piotrowska, Aleksandra; Gomulkiewicz, Agnieszka; Rys, Janusz; Podhorska-Okolow, Marzenna; Dziegiel, Piotr

    2017-10-01

    As a result of activation of transcription factors engaged in epithelial-mesenchymal transition (EMT), such as Twist, inhibition of epithelial markers and an increased expression of mesenchymal markers are observed. One of the specific markers of cancer-associated fibroblasts is podoplanin (PDPN) - a mucin-type membrane glycoprotein. The aim of this work was to study the localisation and intensity of expression of Twist and PDPN on the mRNA and protein level in cases of invasive ductal breast carcinoma (IDC), and its association with patients' clinico-pathological data. The study included archival material in a form of 80 paraffin IDC blocks and 11 IDC fragments frozen in liquid nitrogen. Immunohistochemical expression of Twist and PDPN was evaluated using light microscope and semiquantitative scale for evaluation of nuclear expression or immunoreactive scale (IRS) for evaluation of cytoplasmic expression. Material was isolated from frozen IDC fragments using laser micro-dissection (from cancer and stromal cells, separately) and was used to perform real-time PCR. Twist expression was higher in stromal cells in comparison to cancer cells. Analysis of patients' survival rate showed, that higher expression of Twist in cancer cells was associated with shorter overall survival time and shorter event-free survival time. The expression of PDPN was also higher in stromal cells in comparison with cancer cells. In addition, positive correlation was observed between expression of Twist and PDPN in stromal cells of IDC (r=0.267; p<0.05). The relationship between the higher expression of Twist in both cancer and stromal cells and shorter patients' survival indicates Twist as a potential useful prognostic marker in IDC. Positive correlation of Twist and PDPN expression may indicate the role of PDPN in EMT in IDC. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  10. Twisted entire cyclic cohomology, J-L-O cocycles and equivariant spectral triples

    International Nuclear Information System (INIS)

    Goswami, D.

    2002-07-01

    We study the 'quantized calculus' corresponding to the algebraic ideas related to 'twisted cyclic cohomology'. With very similar definitions and techniques, we define and study 'twisted entire cyclic cohomology' and the 'twisted Chern character' associated with an appropriate operator theoretic data called 'twisted spectral data', which consists of a spectral triple in the conventional sense of noncommutative geometry and an additional positive operator having some specified properties. Furthermore, it is shown that given a spectral triple (in the conventional sense) which is equivariant under the action of a compact matrix pseudogroup, it is possible to obtain a canonical twisted spectral data and hence the corresponding (twisted) Chern character, which will be invariant under the action of the pseudogroup, in contrast to the fact that the Chern character coming from the conventional noncommutative geometry need not be invariant under the above action. (author)

  11. On the space of connections having non-trivial twisted harmonic spinors

    International Nuclear Information System (INIS)

    Bei, Francesco; Waterstraat, Nils

    2015-01-01

    We consider Dirac operators on odd-dimensional compact spin manifolds which are twisted by a product bundle. We show that the space of connections on the twisting bundle which yields an invertible operator has infinitely many connected components if the untwisted Dirac operator is invertible and the dimension of the twisting bundle is sufficiently large

  12. On the space of connections having non-trivial twisted harmonic spinors

    Energy Technology Data Exchange (ETDEWEB)

    Bei, Francesco, E-mail: bei@math.hu-berlin.de [Institut für Mathematik, Humboldt Universität zu Berlin, Unter den Linden 6, 10099 Berlin (Germany); Waterstraat, Nils, E-mail: n.waterstraat@kent.ac.uk [School of Mathematics, Statistics & Actuarial Science, University of Kent, Canterbury, Kent CT2 7NF (United Kingdom)

    2015-09-15

    We consider Dirac operators on odd-dimensional compact spin manifolds which are twisted by a product bundle. We show that the space of connections on the twisting bundle which yields an invertible operator has infinitely many connected components if the untwisted Dirac operator is invertible and the dimension of the twisting bundle is sufficiently large.

  13. Glycosaminoglycan composition of PC12 pheochromocytoma cells: a comparison with PC12D cells, a new subline of PC12 cells

    Energy Technology Data Exchange (ETDEWEB)

    Katoh-Semba, R.; Oohira, A.; Sano, M.; Watanabe, K.; Kitajima, S.; Kashiwamata, S.

    1989-03-01

    PC12D cells, a new subline of conventional PC12 cells, respond not only to nerve growth factor but also to cyclic AMP by extending their neurites. These cells are flat in shape and are similar in appearance to PC12 cells that have been treated with nerve growth factor for a few days. In both cell lines, we have characterized the glycosaminoglycans, the polysaccharide moieties of proteoglycans, which are believed to play an important role in cell adhesion and in cell morphology. Under the present culture conditions, only chondroitin sulfate was detected in the media from PC12 and PC12D cells, whereas both chondroitin sulfate and heparan sulfate were found in the cell layers. The levels of cell-associated heparan sulfate and chondroitin sulfate were about twofold and fourfold higher in PC12D cells than in PC12 cells, respectively. Compared to PC12 cells, the amounts of (/sup 35/S)sulfate incorporated for 48 h into chondroitin sulfate were twofold lower but those into heparan sulfate were 35% higher in PC12D cells. The amount of chondroitin sulfate released by PC12D cells into the medium was about a half of that released by PC12 cells. The ratio of (/sup 35/S)sulfate-labeled heparan sulfate to chondroitin sulfate was 6.2 in PC12D cells and 2.2 in PC12 cells. These results suggest that there may be some correlation between the increase in content of glycosaminoglycans and the change in cell morphology, which is followed by neurite outgrowth.

  14. Aeroelastic Analysis of Helicopter Rotor Blades Incorporating Anisotropic Piezoelectric Twist Actuation

    Science.gov (United States)

    Wilkie, W. Keats; Belvin, W. Keith; Park, K. C.

    1996-01-01

    A simple aeroelastic analysis of a helicopter rotor blade incorporating embedded piezoelectric fiber composite, interdigitated electrode blade twist actuators is described. The analysis consists of a linear torsion and flapwise bending model coupled with a nonlinear ONERA based unsteady aerodynamics model. A modified Galerkin procedure is performed upon the rotor blade partial differential equations of motion to develop a system of ordinary differential equations suitable for dynamics simulation using numerical integration. The twist actuation responses for three conceptual fullscale blade designs with realistic constraints on blade mass are numerically evaluated using the analysis. Numerical results indicate that useful amplitudes of nonresonant elastic twist, on the order of one to two degrees, are achievable under one-g hovering flight conditions for interdigitated electrode poling configurations. Twist actuation for the interdigitated electrode blades is also compared with the twist actuation of a conventionally poled piezoelectric fiber composite blade. Elastic twist produced using the interdigitated electrode actuators was found to be four to five times larger than that obtained with the conventionally poled actuators.

  15. Quadratic Twists of Rigid Calabi–Yau Threefolds Over

    DEFF Research Database (Denmark)

    Gouvêa, Fernando Q.; Kiming, Ian; Yui, Noriko

    2013-01-01

    of weight 4 on some Γ 0(N). We show that quadratic twisting of a threefold corresponds to twisting the attached newform by quadratic characters and illustrate with a number of obvious and not so obvious examples. The question is motivated by the deeper question of which newforms of weight 4 on some Γ 0(N...

  16. VIDEO-PC, SVGA Routines for FORTRAN on PC

    International Nuclear Information System (INIS)

    1994-01-01

    1 - Description of program or function: These primitives are the lowest level routines needed to perform super VGA graphics on a PC. A sample main program is included that exercises the primitives. Both Lahey and Microsoft FORTRAN's have graphics libraries. However, the libraries do not support 256 color graphics at resolutions greater than 320x200. The primitives bypass these libraries while still conforming to standard usage of BIOS. The supported graphics modes depend upon the PC graphics card and its memory. Super VGA resolutions of 640x480 and 800x600 have been tested on an ATI VGA Wonder card with 512 K memory and on several 80486 PC's (unknown manufacturers) at retail stores. 2 - Method of solution: Both Lahey and Microsoft primitives depend upon sending the correct parameters to the PC BIOS (basic input output system) as discussed in the references. 3 - Restrictions on the complexity of the problem: The primitives were developed for 256 color VGA applications. It is known, for instance, that some CGA and 16 color VGA video modes will not operate correctly using these primitives. Potential users should try the test program on their PC/video card combination to determine applicability

  17. Biomimicry 1: PC.

    Science.gov (United States)

    Cumberland, D C; Gunn, J; Malik, N; Holt, C M

    1998-01-01

    The surface properties of stents can be modified by coating them, for example with a polymer. Phosphorylcoline (PC) is the major component of the outer layer of the cell membrane. The haemo- and biocompatibility of a PC-containing polymer is thus based on biomimicry, and has been confirmed by several experiments showing much reduced thrombogenicity of PC-coated surfaces, and porcine coronary artery implants showing no sign of adverse effect. Clinical experience with the PC-coated BiodivYsio appears favourable. The PC coating can be tailored for take up and controlled elution of various drugs for stent-based local delivery, a property which is being actively explored.

  18. The geometric Langlands twist in five and six dimensions

    International Nuclear Information System (INIS)

    Bak, Dongsu; Gustavsson, Andreas

    2015-01-01

    Abelian 6d (2,0) theory has SO(5) R symmetry. We twist this theory by identifying the R symmetry group with the SO(5) subgroup of the SO(1,5) Lorentz group. This twisted theory can be put on any five-manifold M, times R, while preserving one scalar supercharge. We subsequently assume the existence of one unit normalized Killing vector field on M, and we find a corresponding SO(4) twist that preserves two supercharges and is a generalization of the geometric Langlands twist of 4d SYM. We generalize the story to non-Abelian gauge group for the corresponding 5d SYM theories on M. We derive a vanishing theorem for BPS contact instantons by identifying the 6d potential energy and its BPS bound, in the 5d theory. To this end we need to perform a Wick rotation that complexifies the gauge field.

  19. Higher-Twist Dynamics in Large Transverse Momentum Hadron Production

    International Nuclear Information System (INIS)

    Francois, Alero

    2009-01-01

    A scaling law analysis of the world data on inclusive large-p # perpendicular# hadron production in hadronic collisions is carried out. A significant deviation from leading-twist perturbative QCD predictions at next-to-leading order is reported. The observed discrepancy is largest at high values of x # perpendicular# = 2p # perpendicular#/√s. In contrast, the production of prompt photons and jets exhibits the scaling behavior which is close to the conformal limit, in agreement with the leading-twist expectation. These results bring evidence for a non-negligible contribution of higher-twist processes in large-p # perpendicular# hadron production in hadronic collisions, where the hadron is produced directly in the hard subprocess rather than by gluon or quark jet fragmentation. Predictions for scaling exponents at RHIC and LHC are given, and it is suggested to trigger the isolated large-p # perpendicular# hadron production to enhance higher-twist processes.

  20. Periodic solutions of asymptotically linear Hamiltonian systems without twist conditions

    Energy Technology Data Exchange (ETDEWEB)

    Cheng Rong [Coll. of Mathematics and Physics, Nanjing Univ. of Information Science and Tech., Nanjing (China); Dept. of Mathematics, Southeast Univ., Nanjing (China); Zhang Dongfeng [Dept. of Mathematics, Southeast Univ., Nanjing (China)

    2010-05-15

    In dynamical system theory, especially in many fields of applications from mechanics, Hamiltonian systems play an important role, since many related equations in mechanics can be written in an Hamiltonian form. In this paper, we study the existence of periodic solutions for a class of Hamiltonian systems. By applying the Galerkin approximation method together with a result of critical point theory, we establish the existence of periodic solutions of asymptotically linear Hamiltonian systems without twist conditions. Twist conditions play crucial roles in the study of periodic solutions for asymptotically linear Hamiltonian systems. The lack of twist conditions brings some difficulty to the study. To the authors' knowledge, very little is known about the case, where twist conditions do not hold. (orig.)

  1. Prostate carcinoma (PC) - an organ-related specific pathological neoplasm; Prostatakarzinom (PC) - eine organspezifische Neoplasie aus der Sicht der Pathologie

    Energy Technology Data Exchange (ETDEWEB)

    Massmann, J.; Funk, A. [Gemeinschaftspraxis Pathologie Massmann-Funk-Dettmar, Muenchen (Germany); Altwein, J. [Krankenhaus der Barmherzigen Brueder, Muenchen (Germany); Praetorius, M.

    2003-06-01

    The organ- and tumour-related specific characteristics of prostate carcinoma (PC) are presented in an overview under various aspects. It is the key for understanding pathological changes, including PC, to consider the subdivision of the prostate into anatomically and functionally distinguishable zones, especially the transitional zone (TZ) and the peripheral zone (PZ). The pseudoneoplastic hyperplasia of the TZ, combined with inflammatory consequences and age-related changes, forms a differential diagnostic challenge to both clinico-radiological diagnosis and macroscopic and microscopic examination. High-degree prostatic intra-epithelial neoplasia (PIN III) and atypical adenomatous hyperplasia (AAH) are presented as precursor lesions of PC with varying significance and assessment. Moreover, there are discussed the following characteristic features of PC: localisation types, focality, volume, progression, double-graduation according to Gleason, tumour stage, and prognosis. The most important prognosis factors of PC (category I) include the categories of the TNM system, such as stage, surgical marginal situation, degree and also the preoperative PSA level as a (poor) substitute for the tumour volume. Potential prognosis parameters (category II) show the tumour volume and the DNS ploidy, while there continues to exist a large number of non-established parameters (category III). The prognostic validity of the pathological examinations depends, on the one hand, on the tissue extent (needle biopsy, transurethral resection (TURP), so-called simple prostatectomy, radical prostatectomy (RPE)) and the prostate zones covered. On the other hand, the prognostic certainty also depends on the tumour-adequate macroscopic and microscopic assessment of an RPE that can only be a partial or complete handling in transversal large-area sections. (orig.) [German] Die organ- und tumorspezifischen Besonderheiten des Prostatakarzinoms (PC) werden in einer Uebersicht unter verschiedenen

  2. Higher-Twist Distribution Amplitudes of the K Meson in QCD

    CERN Document Server

    Ball, P; Lenz, A; Ball, Patricia

    2006-01-01

    We present a systematic study of twist-3 and twist-4 light-cone distribution amplitudes of the K meson in QCD. The structure of SU(3)-breaking corrections is studied in detail. Non-perturbative input parameters are estimated from QCD sum rules and renormalons. As a by-product, we give a complete reanalysis of the twist-3 and -4 parameters of the pi-meson distribution amplitudes; some of the results differ from those usually quoted in the literature.

  3. Continuous Static Gait with Twisting Trunk of a Metamorphic Quadruped Robot

    Directory of Open Access Journals (Sweden)

    C. Zhang

    2018-01-01

    Full Text Available The natural quadrupeds, such as geckos and lizards, often twist their trunks when moving. Conventional quadruped robots cannot perform the same motion due to equipping with a trunk which is a rigid body or at most consists of two blocks connected by passive joints. This paper proposes a metamorphic quadruped robot with a reconfigurable trunk which can implement active trunk motions, called MetaRobot I. The robot can imitate the natural quadrupeds to execute motion of trunk twisting. Benefiting from the twisting trunk, the stride length of this quadruped is increased comparing to that of conventional quadruped robots.In this paper a continuous static gait benefited from the twisting trunk performing the increased stride length is introduced. After that, the increased stride length relative to the trunk twisting will be analysed mathematically. Other points impacting the implementation of the increased stride length in the gait are investigated such as the upper limit of the stride length and the kinematic margin. The increased stride length in the gait will lead the increase of locomotion speed comparing with conventional quadruped robots, giving the extent that natural quadrupeds twisting their trunks when moving. The simulation and an experiment on the prototype are then carried out to illustrate the benefits on the stride length and locomotion speed brought by the twisting trunk to the quadruped robot.

  4. Cerclage handling for improved fracture treatment. A biomechanical study on the twisting procedure.

    Science.gov (United States)

    Wähnert, D; Lenz, M; Schlegel, U; Perren, S; Windolf, M

    2011-01-01

    Twisting is clinically the most frequently applied method for tightening and maintaining cerclage fixation. The twisting procedure is controversially discussed. Several factors during twisting affect the mechanical behaviour of the cerclage. This in vitro study investigated the influence of different parameters of the twisting procedure on the fixation strength of the cerclage in an experimental setup with centripetal force application. Cortical half shells of the femoral shaft were mounted on a testing fixture. 1.0 mm, 1.25 mm and 1.5 mm stainless ste- el wire cerclages as well as a 1.0mm cable cerclage were applied to the bone. Pretension of the cerclage during the installation was measured during the locking procedure. Subsequently, cyclic testing was performed up to failure. Higher pretension could be achieved with increasing wire diameter. However, with larger wire diameter the drop of pre- tension due to the bending and cutting the twist also increased. The cable cerclage showed the highest pretension after locking. Cerclages twisted under traction revealed significantly higher initial cerclage tension. Plastically deformed twists offered higher cerclage pretension compared to twists which were deformed in the elastic region of the material. Cutting the wire within the twist caused the highest loss of cerclage tension (44% initial tension) whereas only 11 % was lost when cutting the wire ends separately. The bending direction of the twist significantly influenced the cerclage pretension. 45% pretension was lost in forward bending of the twist, 53% in perpendicular bending and 90% in backward bending. Several parameters affect the quality of a cerclage fixation. Adequate installation of cerclage wires could markedly improve the clinical outcome of cerclage.

  5. AKT-ions with a TWIST between EMT and MET.

    Science.gov (United States)

    Tang, Huifang; Massi, Daniela; Hemmings, Brian A; Mandalà, Mario; Hu, Zhengqiang; Wicki, Andreas; Xue, Gongda

    2016-09-20

    The transcription factor Twist is an important regulator of cranial suture during embryogenesis. Closure of the neural tube is achieved via Twist-triggered cellular transition from an epithelial to mesenchymal phenotype, a process known as epithelial-mesenchymal transition (EMT), characterized by a remarkable increase in cell motility. In the absence of Twist activity, EMT and associated phenotypic changes in cell morphology and motility can also be induced, albeit moderately, by other transcription factor families, including Snail and Zeb. Aberrant EMT triggered by Twist in human mammary tumour cells was first reported to drive metastasis to the lung in a metastatic breast cancer model. Subsequent analysis of many types of carcinoma demonstrated overexpression of these unique EMT transcription factors, which statistically correlated with worse outcome, indicating their potential as biomarkers in the clinic. However, the mechanisms underlying their activation remain unclear. Interestingly, increasing evidence indicates they are selectively activated by distinct intracellular kinases, thereby acting as downstream effectors facilitating transduction of cytoplasmic signals into nucleus and reprogramming EMT and mesenchymal-epithelial transition (MET) transcription to control cell plasticity. Understanding these relationships and emerging data indicating differential phosphorylation of Twist leads to complex and even paradoxical functionalities, will be vital to unlocking their potential in clinical settings.

  6. Conductive sub-layer of twisted-tape-induced swirl-flow heat transfer in vertical circular tubes with various twisted-tape inserts

    Science.gov (United States)

    Hata, K.; Fukuda, K.; Masuzaki, S.

    2018-04-01

    Twisted-tape-induced swirl-flow heat transfer due to exponentially increasing heat inputs with various exponential periods ( Q = Q 0 exp(t/τ), τ = 6.04 to 23.07 s) and twisted-tape-induced pressure drop was systematically measured for various mass velocities ( G = 4115 to 13,656 kg/m2 s), inlet liquid temperatures ( T in = 285.88 to 299.09 K), and inlet pressures ( P in = 847.45 to 943.29 kPa) using an experimental water loop flow. Measurements were made over a 59.2-mm effective length and three sections (upper, middle, and lower positions), within which four potential taps were spot-welded onto the outer surface of a 6-mm-inner-diameter, 69.6-mm-heated length, 0.4-mm-thickness platinum circular test tube. Type SUS304 twisted tapes with a width w = 5.6 mm, a thickness δ T = 0.6 mm, a total length l = 372 mm, and twist ratios y = 2.39 and 4.45 were employed in this study. The RANS equations (Reynolds Averaged Navier-Stokes Simulation) with a k-ɛ turbulence model for a circular tube 6 mm in diameter and 636 mm in length were numerically solved for heating of water with a heated section 6 mm in diameter and 70 mm in length using the CFD code, under the same conditions as the experimental ones and considering the temperature dependence of the thermo-physical properties concerned. The theoretical values of surface heat flux q on the circular tubes with twisted tapes with twist ratios y of 2.39 and 4.45 were found to be almost in agreement with the corresponding experimental values of heat flux q, with deviations of less than 30% for the range of temperature difference between the average heater inner surface temperature and the liquid bulk mean temperature ΔT L [ = T s,av - T L , T L = ( T in + T out )/2] considered in this study. The theoretical values of the local surface temperature T s , local average liquid temperature T f,av , and local liquid pressure drop ΔP x were found to be within almost 15% of the corresponding experimental ones. The thickness of the

  7. 'Twisted' strings and higher level Kac-Moody representations

    International Nuclear Information System (INIS)

    Horvath, Z.; Palla, L.

    1989-01-01

    Using an orbifold-like construction the twisted sector of a closed string moving on GxG (with G simply laced) is determined. A level-two G current operating there is constructed explicitly. The decomposition of the twisted sector into products between appropriate conformal and level-two G representations is given if 2 rank G-2 dim G/(2+g)<1. (orig.)

  8. Sox5 induces epithelial to mesenchymal transition by transactivation of Twist1

    International Nuclear Information System (INIS)

    Pei, Xin-Hong; Lv, Xin-Quan; Li, Hui-Xiang

    2014-01-01

    Highlights: • Depletion of Sox5 inhibits breast cancer proliferation, migration, and invasion. • Sox5 transactivates Twist1 expression. • Sox5 induces epithelial to mesenchymal transition through transactivation of Twist1 expression. - Abstract: The epithelial to mesenchymal transition (EMT), a highly conserved cellular program, plays an important role in normal embryogenesis and cancer metastasis. Twist1, a master regulator of embryonic morphogenesis, is overexpressed in breast cancer and contributes to metastasis by promoting EMT. In exploring the mechanism underlying the increased Twist1 in breast cancer cells, we found that the transcription factor SRY (sex-determining region Y)-box 5(Sox5) is up-regulation in breast cancer cells and depletion of Sox5 inhibits breast cancer cell proliferation, migration, and invasion. Furthermore, depletion of Sox5 in breast cancer cells caused a dramatic decrease in Twist1 and chromosome immunoprecipitation assay showed that Sox5 can bind directly to the Twist1 promoter, suggesting that Sox5 transactivates Twist1 expression. We further demonstrated that knockdown of Sox5 up-regulated epithelial phenotype cell biomarker (E-cadherin) and down-regulated mesenchymal phenotype cell biomarkers (N-cadherin, Vimentin, and Fibronectin 1), resulting in suppression of EMT. Our study suggests that Sox5 transactivates Twist1 expression and plays an important role in the regulation of breast cancer progression

  9. Twisted spin Sutherland models from quantum Hamiltonian reduction

    International Nuclear Information System (INIS)

    Feher, L; Pusztai, B G

    2008-01-01

    Recent general results on Hamiltonian reductions under polar group actions are applied to study some reductions of the free particle governed by the Laplace-Beltrami operator of a compact, connected, simple Lie group. The reduced systems associated with arbitrary finite-dimensional irreducible representations of the group by using the symmetry induced by twisted conjugations are described in detail. These systems generically yield integrable Sutherland-type many-body models with spin, which are called twisted spin Sutherland models if the underlying twisted conjugations are built on non-trivial Dynkin diagram automorphisms. The spectra of these models can be calculated, in principle, by solving certain Clebsch-Gordan problems, and the result is presented for the models associated with the symmetric tensorial powers of the defining representation of SU(N)

  10. Extension-twist coupling of composite circular tubes with application to tilt rotor blade design

    Science.gov (United States)

    Nixon, Mark W.

    1987-01-01

    This investigation was conducted to determine if twist deformation required for the design of full-scale extension-twist-coupled tilt-rotor blades can be achieved within material design limit loads, and to demonstrate the accuracy of a coupled-beam analysis in predicting twist deformations. Two extension-twist-coupled tilt-rotor blade designs were developed based on theoretically optimum aerodynamic twist distributions. The designs indicated a twist rate requirement of between .216 and .333 deg/in. Agreement between axial tests and analytical predictions was within 10 percent at design limit loads. Agreement between the torsion tests and predictions was within 11 percent.

  11. PARTIAL ERUPTION OF A FILAMENT WITH TWISTING NON-UNIFORM FIELDS

    International Nuclear Information System (INIS)

    Bi, Yi; Jiang, Yunchun; Yang, Jiayan; Xiang, Yongyuan; Cai, Yunfang; Liu, Weiwei

    2015-01-01

    The eruption of a filament in a kinklike fashion is often regarded as a signature of kink instability. However, the kink instability threshold for the filament’s magnetic structure is not widely understood. Using Hα observations from the New Vacuum Solar Telescope, we present a partial eruptive filament. During the eruption, the filament thread appeared to split from its middle and to break out in a kinklike fashion. In this period, the remaining filament material stayed below and erupted without the kinking motion later on. The coronal magnetic field lines associated with the filament are obtained from nonlinear force-free field extrapolations using the twelve-minute-cadence vector magnetograms of the Helioseismic and Magnetic Imager (HMI) on board the Solar Dynamic Observatory. We studied the extrapolated field lines passing through the magnetic dips which are in good agreement with the observed filament. The field lines are non-uniformly twisted and appear to be composed of two twisted flux ropes winding around each other. One of them has a higher twist than the other, and the flux rope with the higher twist has its dips aligned with the kinking eruptive thread at the beginning of its eruption. Before the eruption, moreover, the flux rope with the higher twist was found to expand with an approximately constant field twist. In addition, the helicity flux maps deduced from the HMI magnetograms show that some helicity is injected into the overlying magnetic arcade, but no significant helicity is injected into the flux ropes. Accordingly, we suggest that the highly twisted flux rope became kink unstable when the instability threshold declined with the expansion of the flux rope

  12. Dynamical twisted mass fermions with light quarks. Simulation and analysis details

    Energy Technology Data Exchange (ETDEWEB)

    Boucaud, P. [Paris-11 Univ., 91 - Orsay (France). Lab. de Physique Theorique; Dimopoulos, P. [Rome-2 Univ. (Italy). Dipt. di Fisica; Farchioni, F. [Muenster Univ. (DE). Inst. fuer Theoretische Physik] (and others)

    2008-03-15

    In a recent paper (2007) we presented precise lattice QCD results of our European Twisted Mass Collaboration (ETMC). They were obtained by employing two mass-degenerate flavours of twisted mass fermions at maximal twist. In the present paper we give details on our simulations and the computation of physical observables. In particular, we discuss the problem of tuning to maximal twist, the techniques we have used to compute correlators and error estimates. In addition, we provide more information on the algorithm used, the autocorrelation times and scale determination, the evaluation of disconnected contributions and the description of our data by means of chiral perturbation theory formulae. (orig.)

  13. Dynamical twisted mass fermions with light quarks. Simulation and analysis details

    International Nuclear Information System (INIS)

    Boucaud, P.; Dimopoulos, P.; Farchioni, F.

    2008-03-01

    In a recent paper (2007) we presented precise lattice QCD results of our European Twisted Mass Collaboration (ETMC). They were obtained by employing two mass-degenerate flavours of twisted mass fermions at maximal twist. In the present paper we give details on our simulations and the computation of physical observables. In particular, we discuss the problem of tuning to maximal twist, the techniques we have used to compute correlators and error estimates. In addition, we provide more information on the algorithm used, the autocorrelation times and scale determination, the evaluation of disconnected contributions and the description of our data by means of chiral perturbation theory formulae. (orig.)

  14. Composite material bend-twist coupling for wind turbine blade applications

    Science.gov (United States)

    Walsh, Justin M.

    Current efforts in wind turbine blade design seek to employ bend-twist coupling of composite materials for passive power control by twisting blades to feather. Past efforts in this area of study have proved to be problematic, especially in formulation of the bend-twist coupling coefficient alpha. Kevlar/epoxy, carbon/epoxy and glass/epoxy specimens were manufactured to study bend-twist coupling, from which numerical and analytical models could be verified. Finite element analysis was implemented to evaluate fiber orientation and material property effects on coupling magnitude. An analytical/empirical model was then derived to describe numerical results and serve as a replacement for the commonly used coupling coefficient alpha. Through the results from numerical and analytical models, a foundation for aeroelastic design of wind turbines blades utilizing biased composite materials is provided.

  15. Flux Density through Guides with Microstructured Twisted Clad DB Medium

    Directory of Open Access Journals (Sweden)

    M. A. Baqir

    2014-01-01

    Full Text Available The paper deals with the study of flux density through a newly proposed twisted clad guide containing DB medium. The inner core and the outer clad sections are usual dielectrics, and the introduced twisted windings at the core-clad interface are treated under DB boundary conditions. The pitch angle of twist is supposed to greatly contribute towards the control over the dispersion characteristics of the guide. The eigenvalue equation for the guiding structure is deduced, and the analytical investigations are made to explore the propagation patterns of flux densities corresponding to the sustained low-order hybrid modes under the situation of varying pitch angles. The emphasis has been put on the effects due to the DB twisted pitch on the propagation of energy flux density through the guide.

  16. Accelerated 3D-OSEM image reconstruction using a Beowulf PC cluster for pinhole SPECT

    International Nuclear Information System (INIS)

    Zeniya, Tsutomu; Watabe, Hiroshi; Sohlberg, Antti; Iida, Hidehiro

    2007-01-01

    A conventional pinhole single-photon emission computed tomography (SPECT) with a single circular orbit has limitations associated with non-uniform spatial resolution or axial blurring. Recently, we demonstrated that three-dimensional (3D) images with uniform spatial resolution and no blurring can be obtained by complete data acquired using two-circular orbit, combined with the 3D ordered subsets expectation maximization (OSEM) reconstruction method. However, a long computation time is required to obtain the reconstruction image, because of the fact that 3D-OSEM is an iterative method and two-orbit acquisition doubles the size of the projection data. To reduce the long reconstruction time, we parallelized the two-orbit pinhole 3D-OSEM reconstruction process by using a Beowulf personal computer (PC) cluster. The Beowulf PC cluster consists of seven PCs connected to Gbit Ethernet switches. Message passing interface protocol was utilized for parallelizing the reconstruction process. The projection data in a subset are distributed to each PC. The partial image forward-and back-projected in each PC is transferred to all PCs. The current image estimate on each PC is updated after summing the partial images. The performance of parallelization on the PC cluster was evaluated using two independent projection data sets acquired by a pinhole SPECT system with two different circular orbits. Parallelization using the PC cluster improved the reconstruction time with increasing number of PCs. The reconstruction time of 54 min by the single PC was decreased to 10 min when six or seven PCs were used. The speed-up factor was 5.4. The reconstruction image by the PC cluster was virtually identical with that by the single PC. Parallelization of 3D-OSEM reconstruction for pinhole SPECT using the PC cluster can significantly reduce the computation time, whereas its implementation is simple and inexpensive. (author)

  17. Promotion of double-duplex invasion of peptide nucleic acids through conjugation with nuclear localization signal peptide.

    Science.gov (United States)

    Aiba, Yuichiro; Honda, Yuta; Komiyama, Makoto

    2015-03-02

    Pseudo-complementary peptide nucleic acid (pcPNA), as one of the most widely used synthetic DNA analogues, invades double-stranded DNA according to Watson-Crick rules to form invasion complexes. This unique mode of DNA recognition induces structural changes at the invasion site and can be used for a range of applications. In this paper, pcPNA is conjugated with a nuclear localization signal (NLS) peptide, and its invading activity is notably promoted both thermodynamically and kinetically. Thus, the double-duplex invasion complex is formed promptly at low pcPNA concentrations under high salt conditions, where the invasion otherwise never occurs. Furthermore, NLS-modified pcPNA is successfully employed for site-selective DNA scission, and the targeted DNA is selectively cleaved under conditions that are not conducive for DNA cutters using unmodified pcPNAs. This strategy of pcPNA modification is expected to be advantageous and promising for a range of in vitro and in vivo applications. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Chirality-controlled spontaneous twisting of crystals due to thermal topochemical reaction.

    Science.gov (United States)

    Rai, Rishika; Krishnan, Baiju P; Sureshan, Kana M

    2018-03-20

    Crystals that show mechanical response against various stimuli are of great interest. These stimuli induce polymorphic transitions, isomerizations, or chemical reactions in the crystal and the strain generated between the daughter and parent domains is transcribed into mechanical response. We observed that the crystals of modified dipeptide LL (N 3 -l-Ala-l-Val-NHCH 2 C≡CH) undergo spontaneous twisting to form right-handed twisted crystals not only at room temperature but also at 0 °C over time. Using various spectroscopic techniques, we have established that the twisting is due to the spontaneous topochemical azide-alkyne cycloaddition (TAAC) reaction at room temperature or lower temperatures. The rate of twisting can be increased by heating, exploiting the faster kinetics of the TAAC reaction at higher temperatures. To address the role of molecular chirality in the direction of twisting the enantiomer of dipeptide LL, N 3 -d-Ala-d-Val-NHCH 2 C≡CH (DD), was synthesized and topochemical reactivity and mechanoresponse of its crystals were studied. We have found that dipeptide DD not only underwent TAAC reaction, giving 1,4-triazole-linked pseudopolypeptides of d-amino acids, but also underwent twisting with opposite handedness (left-handed twisting), establishing the role of molecular chirality in controlling the direction of mechanoresponse. This paper reports ( i ) a mechanical response due to a thermal reaction and ( ii ) a spontaneous mechanical response in crystals and ( iii ) explains the role of molecular chirality in the handedness of the macroscopic mechanical response.

  19. On the twists of interplanetary magnetic flux ropes observed at 1 AU

    Science.gov (United States)

    Wang, Yuming; Zhuang, Bin; Hu, Qiang; Liu, Rui; Shen, Chenglong; Chi, Yutian

    2016-10-01

    Magnetic flux ropes (MFRs) are one kind of fundamental structures in the solar/space physics and involved in various eruption phenomena. Twist, characterizing how the magnetic field lines wind around a main axis, is an intrinsic property of MFRs, closely related to the magnetic free energy and stableness. Although the effect of the twist on the behavior of MFRs had been widely studied in observations, theory, modeling, and numerical simulations, it is still unclear how much amount of twist is carried by MFRs in the solar atmosphere and in heliosphere and what role the twist played in the eruptions of MFRs. Contrasting to the solar MFRs, there are lots of in situ measurements of magnetic clouds (MCs), the large-scale MFRs in interplanetary space, providing some important information of the twist of MFRs. Thus, starting from MCs, we investigate the twist of interplanetary MFRs with the aid of a velocity-modified uniform-twist force-free flux rope model. It is found that most of MCs can be roughly fitted by the model and nearly half of them can be fitted fairly well though the derived twist is probably overestimated by a factor of 2.5. By applying the model to 115 MCs observed at 1 AU, we find that (1) the twist angles of interplanetary MFRs generally follow a trend of about 0.6l/R radians, where l/R is the aspect ratio of a MFR, with a cutoff at about 12π radians AU-1, (2) most of them are significantly larger than 2.5π radians but well bounded by 2l/R radians, (3) strongly twisted magnetic field lines probably limit the expansion and size of MFRs, and (4) the magnetic field lines in the legs wind more tightly than those in the leading part of MFRs. These results not only advance our understanding of the properties and behavior of interplanetary MFRs but also shed light on the formation and eruption of MFRs in the solar atmosphere. A discussion about the twist and stableness of solar MFRs are therefore given.

  20. Twisting the Mirror TBA

    NARCIS (Netherlands)

    Arutyunov, G.E.; de Leeuw, M.; van Tongeren, S.J.

    2010-01-01

    We study finite-size corrections to the magnon dispersion relation in three models which differ from string theory on AdS5 x S5 in their boundary conditions. Asymptotically, this is accomplished by twisting the transfer matrix in a way which manifestly preserves integrability. In model I all

  1. Finite element and analytical models for twisted and coiled actuator

    Science.gov (United States)

    Tang, Xintian; Liu, Yingxiang; Li, Kai; Chen, Weishan; Zhao, Jianguo

    2018-01-01

    Twisted and coiled actuator (TCA) is a class of recently discovered artificial muscle, which is usually made by twisting and coiling polymer fibers into spring-like structures. It has been widely studied since discovery due to its impressive output characteristics and bright prospects. However, its mathematical models describing the actuation in response to the temperature are still not fully developed. It is known that the large tensile stroke is resulted from the untwisting of the twisted fiber when heated. Thus, the recovered torque during untwisting is a key parameter in the mathematical model. This paper presents a simplified model for the recovered torque of TCA. Finite element method is used for evaluating the thermal stress of the twisted fiber. Based on the results of the finite element analyses, the constitutive equations of twisted fibers are simplified to develop an analytic model of the recovered torque. Finally, the model of the recovered torque is used to predict the deformation of TCA under varying temperatures and validated against experimental results. This work will enhance our understanding of the deformation mechanism of TCAs, which will pave the way for the closed-loop position control.

  2. New dualities and misleading anomaly matchings from outer-automorphism twists

    Energy Technology Data Exchange (ETDEWEB)

    Pal, Sridip; Song, Jaewon [Department of Physics, University of California, San Diego,La Jolla, CA 92093 (United States)

    2017-03-29

    We study four-dimensional N=1,2 superconformal theories in class S obtained by compactifying the 6d N=(2,0) theory on a Riemann surface C with outer-automorphism twist lines. From the pair-of-pants decompositions of C, we find various dual descriptions for the same theory having distinct gauge groups. We show that the various configurations of the twist line give rise to dual descriptions for the identical theory. We compute the ’t Hooft anomaly coefficients and the superconformal indices to test dualities. Surprisingly, we find that the class S theories with twist lines wrapping 1-cycles of C have the identical ’t Hooft anomalies as the ones without the twist line, whereas the superconformal indices differ. This provides a large set of examples where the anomaly matching is insufficient to test dualities.

  3. Leading twist moments of the neutron structure function F_2n

    Energy Technology Data Exchange (ETDEWEB)

    M. Osipenko; W. Melnitchouk; S. Simula; S. Kulagin; G. Ricco

    2005-10-20

    We perform a global analysis of neutron $F_2^n$ structure function data, obtained by combining proton and deuteron measurements over a large range of kinematics. From these data the lowest moments ($n \\leq 10$) of the leading twist neutron $F_2^n$ structure function are extracted. Particular attention is paid to nuclear effects in the deuteron, which become increasingly important for the higher moments. Our results for the nonsinglet, isovector $p - n$ combination of the leading twist moments are compared with those of available lattice simulations. We also determine the lowest few moments of the higher twist contributions, obtained by subtracting the leading twist from the total structure function, and analyze their isospin dependence.

  4. Intermittent energy bursts and recurrent topological change of a twisting magnetic flux tube

    International Nuclear Information System (INIS)

    Amo, Hiroyoshi; Sato, Tetsuya; Kageyama, Akira.

    1994-09-01

    When continuously twisted, a magnetic flux tube suffers a large kink distortion in the middle part of the tube, like a knot-of-tension instability of a bundle of twisted rubber strings, and reconnection is triggered starting with the twisted field lines and quickly proceeding to the untwisted field lines at the twist-untwist boundary, whereby a giant burst-like energy release takes place. Subsequently, bursts occur intermittently and reconnection advances deeper into the untwisted region. Then, a companion pair of the linked twist-untwist flux tubes reconnect with each other to return to the original axisymmetric tube. The process is thus repeatable. (author)

  5. Construction and identification of eukaryotic expression vector of pcDNA3-UHRF1

    International Nuclear Information System (INIS)

    Li Xinli; Zhu Ran; Zhu Wei; Fan Saijun; Meng Qinghui

    2011-01-01

    Objective: To generate eukaryotic expression vector of pcDNA3-UHRF1(ubiquitin-like, containing PHD and RING finger domains 1, UHRF1) and testify its expression in breast cancer cells MDA-MB-231. Methods: A 2.3 kb cDNA fragment was amplified from the total RNA of the human breast cancer cells MCF-7 by the RT-PCR method and was cloned into the plasmid pcDNA3. The vector was identified by the double digestion with restriction enzymes Kpn I and Xho I and was sequenced. The cDNA of UHRF1 was transfected into human breast cancer cells MDA-MB-231 by Lipofactamin2000. The positive clones were selected by G418. The expression of the UHRF1 was detected by RT-PCR and Western blot analysis. Results: The recombinant eukaryotic expression vector pcDNA3-UHRF1 was digested with Kpn I and BamH I, and the electrophoresis of the digested products showed two fragments; 2.3kb fragment of UHRF1 and 5.4 kb fragment of pcDNA3, and the sequence inserted was identical to the published sequence. The MDA-MB-231 cells transfected with the pcDNA3-UHRF1 plasmid expressed a high level of the UHRF1 mRNA and protein. Conclusion: The recombinant eukaryotic cell expression vector of pcDNA3-UHRF1 is constructed successfully. The recombinant plasmid pcDNA3-UHRF1 can provide a very useful tool and lay an important foundation for the research on the function of UHRF1. (authors)

  6. Understanding Financial Market States Using an Artificial Double Auction Market.

    Science.gov (United States)

    Yim, Kyubin; Oh, Gabjin; Kim, Seunghwan

    2016-01-01

    The ultimate value of theories describing the fundamental mechanisms behind asset prices in financial systems is reflected in the capacity of such theories to understand these systems. Although the models that explain the various states of financial markets offer substantial evidence from the fields of finance, mathematics, and even physics, previous theories that attempt to address the complexities of financial markets in full have been inadequate. We propose an artificial double auction market as an agent-based model to study the origin of complex states in financial markets by characterizing important parameters with an investment strategy that can cover the dynamics of the financial market. The investment strategies of chartist traders in response to new market information should reduce market stability based on the price fluctuations of risky assets. However, fundamentalist traders strategically submit orders based on fundamental value and, thereby stabilize the market. We construct a continuous double auction market and find that the market is controlled by the proportion of chartists, Pc. We show that mimicking the real state of financial markets, which emerges in real financial systems, is given within the range Pc = 0.40 to Pc = 0.85; however, we show that mimicking the efficient market hypothesis state can be generated with values less than Pc = 0.40. In particular, we observe that mimicking a market collapse state is created with values greater than Pc = 0.85, at which point a liquidity shortage occurs, and the phase transition behavior is described at Pc = 0.85.

  7. Understanding Financial Market States Using an Artificial Double Auction Market.

    Directory of Open Access Journals (Sweden)

    Kyubin Yim

    Full Text Available The ultimate value of theories describing the fundamental mechanisms behind asset prices in financial systems is reflected in the capacity of such theories to understand these systems. Although the models that explain the various states of financial markets offer substantial evidence from the fields of finance, mathematics, and even physics, previous theories that attempt to address the complexities of financial markets in full have been inadequate. We propose an artificial double auction market as an agent-based model to study the origin of complex states in financial markets by characterizing important parameters with an investment strategy that can cover the dynamics of the financial market. The investment strategies of chartist traders in response to new market information should reduce market stability based on the price fluctuations of risky assets. However, fundamentalist traders strategically submit orders based on fundamental value and, thereby stabilize the market. We construct a continuous double auction market and find that the market is controlled by the proportion of chartists, Pc. We show that mimicking the real state of financial markets, which emerges in real financial systems, is given within the range Pc = 0.40 to Pc = 0.85; however, we show that mimicking the efficient market hypothesis state can be generated with values less than Pc = 0.40. In particular, we observe that mimicking a market collapse state is created with values greater than Pc = 0.85, at which point a liquidity shortage occurs, and the phase transition behavior is described at Pc = 0.85.

  8. A Transformation Called "Twist"

    Science.gov (United States)

    Hwang, Daniel

    2010-01-01

    The transformations found in secondary mathematics curriculum are typically limited to stretches and translations (e.g., ACARA, 2010). Advanced students may find the transformation, twist, to be of further interest. As most available resources are written for professional-level readers, this article is intended to be an introduction accessible to…

  9. Bioinspired twisted composites based on Bouligand structures

    Science.gov (United States)

    Pinto, F.; Iervolino, O.; Scarselli, G.; Ginzburg, D.; Meo, M.

    2016-04-01

    The coupling between structural support and protection makes biological systems an important source of inspiration for the development of advanced smart composite structures. In particular, some particular material configurations can be implemented into traditional composites in order to improve their impact resistance and the out-of-plane properties, which represents one of the major weakness of commercial carbon fibres reinforced polymers (CFRP) structures. Based on this premise, a three-dimensional twisted arrangement shown in a vast multitude of biological systems (such as the armoured cuticles of Scarabei, the scales of Arapaima Gigas and the smashing club of Odontodactylus Scyllarus) has been replicated to develop an improved structural material characterised by a high level of in-plane isotropy and a higher interfacial strength generated by the smooth stiffness transition between each layer of fibrils. Indeed, due to their intrinsic layered nature, interlaminar stresses are one of the major causes of failure of traditional CFRP and are generated by the mismatch of the elastic properties between plies in a traditional laminate. Since the energy required to open a crack or a delamination between two adjacent plies is due to the difference between their orientations, the gradual angle variation obtained by mimicking the Bouligand Structures could improve energy absorption and the residual properties of carbon laminates when they are subjected to low velocity impact event. Two different bioinspired laminates were manufactured following a double helicoidal approach and a rotational one and were subjected to a complete test campaign including low velocity impact loading and compared to a traditional quasi-isotropic panel. Fractography analysis via X-Ray tomography was used to understand the mechanical behaviour of the different laminates and the residual properties were evaluated via Compression After Impact (CAI) tests. Results confirmed that the biological

  10. Stability of coupled tearing and twisting modes in tokamaks

    International Nuclear Information System (INIS)

    Fitzpatrick, R.

    1994-03-01

    A dispersion relation is derived for resistive modes of arbitrary parity in a tokamak plasma. At low mode amplitude, tearing and twisting modes which have nonideal MHD behavior at only one rational surface at a time in the plasma are decoupled via sheared rotation and diamagnetic flows. At higher amplitude, more unstable open-quote compound close-quote modes develop which have nonideal behavior simultaneously at many surfaces. Such modes possess tearing parity layers at some of the nonideal surfaces, and twisting parity layers at others, but mixed parity layers are generally disallowed. At low mode number, open-quote compound close-quote modes are likely to have tearing parity layers at all of the nonideal surfaces in a very low-β plasma, but twisting parity layers become more probable as the plasma β is increased. At high mode number, unstable twisting modes which exceed a critical amplitude drive conventional magnetic island chains on alternate rational surfaces, to form an interlocking structure in which the O-points and X-points of neighboring chains line up

  11. Design optimization for active twist rotor blades

    Science.gov (United States)

    Mok, Ji Won

    This dissertation introduces the process of optimizing active twist rotor blades in the presence of embedded anisotropic piezo-composite actuators. Optimum design of active twist blades is a complex task, since it involves a rich design space with tightly coupled design variables. The study presents the development of an optimization framework for active helicopter rotor blade cross-sectional design. This optimization framework allows for exploring a rich and highly nonlinear design space in order to optimize the active twist rotor blades. Different analytical components are combined in the framework: cross-sectional analysis (UM/VABS), an automated mesh generator, a beam solver (DYMORE), a three-dimensional local strain recovery module, and a gradient based optimizer within MATLAB. Through the mathematical optimization problem, the static twist actuation performance of a blade is maximized while satisfying a series of blade constraints. These constraints are associated with locations of the center of gravity and elastic axis, blade mass per unit span, fundamental rotating blade frequencies, and the blade strength based on local three-dimensional strain fields under worst loading conditions. Through pre-processing, limitations of the proposed process have been studied. When limitations were detected, resolution strategies were proposed. These include mesh overlapping, element distortion, trailing edge tab modeling, electrode modeling and foam implementation of the mesh generator, and the initial point sensibility of the current optimization scheme. Examples demonstrate the effectiveness of this process. Optimization studies were performed on the NASA/Army/MIT ATR blade case. Even though that design was built and shown significant impact in vibration reduction, the proposed optimization process showed that the design could be improved significantly. The second example, based on a model scale of the AH-64D Apache blade, emphasized the capability of this framework to

  12. κ-Minkowski spacetime as the result of Jordanian twist deformation

    International Nuclear Information System (INIS)

    Borowiec, A.; Pachol, A.

    2009-01-01

    Two one-parameter families of twists providing κ-Minkowski * product deformed spacetime are considered: Abelian and Jordanian. We compare the derivation of quantum Minkowski space from two perspectives. The first one is the Hopf module algebra point of view, which is strictly related with Drinfeld's twisting tensor technique. The other one relies on an appropriate extension of ''deformed realizations'' of nondeformed Lorentz algebra by the quantum Minkowski algebra. This extension turns out to be de Sitter Lie algebra. We show the way both approaches are related. The second path allows us to calculate deformed dispersion relations for toy models ensuing from different twist parameters. In the Abelian case, one recovers κ-Poincare dispersion relations having numerous applications in doubly special relativity. Jordanian twists provide a new type of dispersion relations which in the minimal case (related to Weyl-Poincare algebra) takes an energy-dependent linear mass deformation form.

  13. Performance improvement of small-scale rotors by passive blade twist control

    OpenAIRE

    Lv, Peng; Prothin, Sebastien; Mohd Zawawi, Fazila; Bénard, Emmanuel; Morlier, Joseph; Moschetta, Jean-Marc

    2015-01-01

    A passive twist control is proposed as an adaptive way to maximize the overall efficiency of the small-scale rotor blade for multifunctional aircrafts. Incorporated into a database of airfoil characteristics, Blade Element Momentum Theory is implemented to obtain the blade optimum twist rates for hover and forward flight. In order to realize the required torsion of blade between hover and forward flight, glass/epoxy laminate blade is proposed based on Centrifugal Force Induced Twist concept. ...

  14. Unique CCT repeats mediate transcription of the TWIST1 gene in mesenchymal cell lines

    International Nuclear Information System (INIS)

    Ohkuma, Mizue; Funato, Noriko; Higashihori, Norihisa; Murakami, Masanori; Ohyama, Kimie; Nakamura, Masataka

    2007-01-01

    TWIST1, a basic helix-loop-helix transcription factor, plays critical roles in embryo development, cancer metastasis and mesenchymal progenitor differentiation. Little is known about transcriptional regulation of TWIST1 expression. Here we identified DNA sequences responsible for TWIST1 expression in mesenchymal lineage cell lines. Reporter assays with TWIST1 promoter mutants defined the -102 to -74 sequences that are essential for TWIST1 expression in human and mouse mesenchymal cell lines. Tandem repeats of CCT, but not putative CREB and NF-κB sites in the sequences substantially supported activity of the TWIST1 promoter. Electrophoretic mobility shift assay demonstrated that the DNA sequences with the CCT repeats formed complexes with nuclear factors, containing, at least, Sp1 and Sp3. These results suggest critical implication of the CCT repeats in association with Sp1 and Sp3 factors in sustaining expression of the TWIST1 gene in mesenchymal cells

  15. Valve-aided twisted Savonius rotor

    Energy Technology Data Exchange (ETDEWEB)

    Jaya Rajkumar, M.; Saha, U.K.

    2006-05-15

    Accessories, such as end plates, deflecting plates, shielding and guide vanes, may increase the power of a Savonius rotor, but make the system structurally complex. In such cases, the rotor can develop a relatively large torque at small rotational speeds and is cheap to build, however it harnesses only a small fraction of the incident wind energy. Another proposition for increasing specific output is to place non-return valves inside the concave side of the blades. Such methods have been studied experimentally with a twisted-blade Thus improving a Savonius rotor's energy capture. This new concept has been named as the 'Valve-Aided Twisted Savonius'rotor. Tests were conducted in a low-speed wind tunnel to evaluate performance. This mechanism is found to be independent of flow direction, and shows potential for large machines. [Author].

  16. Twisting failure of centrally loaded open-section columns in the elastic range

    Science.gov (United States)

    Kappus, Robert

    1938-01-01

    In the following report a complete theory of twisting failure by the energy method is developed, based on substantially the same assumptions as those employed by Wagner and Bleich. Problems treated in detail are: the stress and strain condition under St. Venant twist and in twist with axial constraint; the concept of shear center and the energy method for problems of elastic stability.

  17. Local Gate Control of a Carbon Nanotube Double Quantum Dot

    Science.gov (United States)

    2016-04-04

    describ- ing the levitation . Quantitative comparisons are made difficult by the complicated aniso- tropy of the nematic’s viscoelasticity (21). However...director fields. For example, as a straightforward extension of the levitation , a liquid crystal that twists through many periods (such as a cholesteric...Nanotube Double Quantum Dot N. Mason,*† M. J. Biercuk,* C. M. Marcus† We have measured carbon nanotube quantum dots with multiple electro- static gates and

  18. Exploring exotic states with twisted boundary conditions

    International Nuclear Information System (INIS)

    Agadjanov, Dimitri

    2017-01-01

    he goal of this thesis is to develop methods to study the nature and properties of exotic hadrons from lattice simulations. The main focus lies in the application of twisted boundary conditions. The thesis consists of a general introduction and the collection of three papers, represented respectively in three chapters. The introduction of the thesis reviews the theoretical background, which is further used in the rest of the thesis. Further implementing partially twisted boundary conditions in the scalar sector of lattice QCD is studied. Then we develop a method to study the content of the exotic hadrons by determining the wave function renormalization constant from lattice simulations, exploiting the dependence of the spectrum on the twisted boundary conditions. The final chapter deals with a novel method to study the multi-channel scattering problem in a finite volume, which is relevant for exotic states. Its key idea is to extract the complex hadron-hadron optical potential, avoiding the difficulties, associated with the solution of the multi-channel Luescher equation.

  19. Exploring exotic states with twisted boundary conditions

    Energy Technology Data Exchange (ETDEWEB)

    Agadjanov, Dimitri

    2017-09-11

    he goal of this thesis is to develop methods to study the nature and properties of exotic hadrons from lattice simulations. The main focus lies in the application of twisted boundary conditions. The thesis consists of a general introduction and the collection of three papers, represented respectively in three chapters. The introduction of the thesis reviews the theoretical background, which is further used in the rest of the thesis. Further implementing partially twisted boundary conditions in the scalar sector of lattice QCD is studied. Then we develop a method to study the content of the exotic hadrons by determining the wave function renormalization constant from lattice simulations, exploiting the dependence of the spectrum on the twisted boundary conditions. The final chapter deals with a novel method to study the multi-channel scattering problem in a finite volume, which is relevant for exotic states. Its key idea is to extract the complex hadron-hadron optical potential, avoiding the difficulties, associated with the solution of the multi-channel Luescher equation.

  20. Measurement of curvature and twist of a deformed object using digital holography

    International Nuclear Information System (INIS)

    Chen Wen; Quan Chenggen; Cho Jui Tay

    2008-01-01

    Measurement of curvature and twist is an important aspect in the study of object deformation. In recent years, several methods have been proposed to determine curvature and twist of a deformed object using digital shearography. Here we propose a novel method to determine the curvature and twist of a deformed object using digital holography and a complex phasor. A sine/cosine transformation method and two-dimensional short time Fourier transform are proposed subsequently to process the wrapped phase maps. It is shown that high-quality phase maps corresponding to curvature and twist can be obtained. An experiment is conducted to demonstrate the validity of the proposed method

  1. Structural and electronic transformation in low-angle twisted bilayer graphene

    Science.gov (United States)

    Gargiulo, Fernando; Yazyev, Oleg V.

    2018-01-01

    Experiments on bilayer graphene unveiled a fascinating realization of stacking disorder where triangular domains with well-defined Bernal stacking are delimited by a hexagonal network of strain solitons. Here we show by means of numerical simulations that this is a consequence of a structural transformation of the moiré pattern inherent to twisted bilayer graphene taking place at twist angles θ below a crossover angle θ\\star=1.2\\circ . The transformation is governed by the interplay between the interlayer van der Waals interaction and the in-plane strain field, and is revealed by a change in the functional form of the twist energy density. This transformation unveils an electronic regime characteristic of vanishing twist angles in which the charge density converges, though not uniformly, to that of ideal bilayer graphene with Bernal stacking. On the other hand, the stacking domain boundaries form a distinct charge density pattern that provides the STM signature of the hexagonal solitonic network.

  2. Innovation of Methods for Measurement and Modelling of Twisted Pair Parameters

    Directory of Open Access Journals (Sweden)

    Lukas Cepa

    2011-01-01

    Full Text Available The goal of this paper is to optimize a measurement methodology for the most accurate broadband modelling of characteristic impedance and other parameters for twisted pairs. Measured values and theirs comparison is presented in this article. Automated measurement facility was implemented at the Department of telecommunication of Faculty of electrical engineering of Czech technical university in Prague. Measurement facility contains RF switches allowing measurements up to 300 MHz or 1GHz. Measured twisted pair’s parameters can be obtained by measurement but for purposes of fundamental characteristics modelling is useful to define functions that model the properties of the twisted pair. Its primary and secondary parameters depend mostly on the frequency. For twisted pair deployment, we are interested in a frequency band range from 1 MHz to 100 MHz.

  3. Unconfined twist : a simple method to prepare ultrafine grained metallic materials.

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Y. (Yonghao); Liao, Xiaozhou; Zhu, Y. T. (Yuntian Theodore)

    2004-01-01

    A new simple method - unconfined twist was employed to prepare ultrafine grained (UFG) Fe,wire. A coarse grained (CG) Fe wire with a diameter of 0.85 mm was fixed at one end, and twisted at the other end. After maximum twist before fracture, in the cross-sectional plane, concentrically deformed layers with a width of several micrometers formed surrounding the center axis of the wire. The near-surface deformed layers consist of lamella grains with a width in submicrometer range. In the longitudinal plane, deformed bands (with a width of several micrometers) formed uniformly, which were composed of lamella crystallites (with a width in submicrometer range). The tensile yield strength and ultimate strength of the twisted Fe wire are increased by about 150% and 100% compared with the values of its CG counterpart.

  4. Anisotropic piezoelectric twist actuation of helicopter rotor blades: Aeroelastic analysis and design optimization

    Science.gov (United States)

    Wilkie, William Keats

    1997-12-01

    An aeroelastic model suitable for control law and preliminary structural design of composite helicopter rotor blades incorporating embedded anisotropic piezoelectric actuator laminae is developed. The aeroelasticity model consists of a linear, nonuniform beam representation of the blade structure, including linear piezoelectric actuation terms, coupled with a nonlinear, finite-state unsteady aerodynamics model. A Galerkin procedure and numerical integration in the time domain are used to obtain a soluti An aeroelastic model suitable for control law and preliminary structural design of composite helicopter rotor blades incorporating embedded anisotropic piezoelectric actuator laminae is developed. The aeroelasticity model consists of a linear, nonuniform beam representation of the blade structure, including linear piezoelectric actuation terms, coupled with a nonlinear, finite-state unsteady aerodynamics model. A Galerkin procedure and numerical integration in the time domain are used to obtain amited additional piezoelectric material mass, it is shown that blade twist actuation approaches which exploit in-plane piezoelectric free-stain anisotropies are capable of producing amplitudes of oscillatory blade twisting sufficient for rotor vibration reduction applications. The second study examines the effectiveness of using embedded piezoelectric actuator laminae to alleviate vibratory loads due to retreating blade stall. A 10 to 15 percent improvement in dynamic stall limited forward flight speed, and a 5 percent improvement in stall limited rotor thrust were numerically demonstrated for the active twist rotor blade relative to a conventional blade design. The active twist blades are also demonstrated to be more susceptible than the conventional blades to dynamic stall induced vibratory loads when not operating with twist actuation. This is the result of designing the active twist blades with low torsional stiffness in order to maximize piezoelectric twist authority

  5. Effective potentials for twisted fields

    International Nuclear Information System (INIS)

    Banach, R.

    1981-01-01

    Minus the density of the effective action, evaluated at the lowest eigenfunction of the (space-time) derivative part of the second (functional) derivative of the classical action, is proposed as a generalised definition of the effective potential, applicable to twisted as well as untwisted sectors of a field theory. The proposal is corroborated by several specific calculations in the twisted sector, namely phi 4 theory (real and complex) and wrong-sign-Gordon theory, in an Einstein cylinder, where the exact integrability of the static solutions confirms the effective potential predictions. Both models exhibit a phase transition, which the effective potential locates, and the one-loop quantum shift in the critical radius is computed for the real phi 4 model, being a universal result. Topological mass generation at the classical level is pointed out, and the exactness of the classical effective potential approximation for complex phi 4 is discussed. (author)

  6. Quantum communication through a spin ring with twisted boundary conditions

    International Nuclear Information System (INIS)

    Bose, S.; Jin, B.-Q.; Korepin, V.E.

    2005-01-01

    We investigate quantum communication between the sites of a spin ring with twisted boundary conditions. Such boundary conditions can be achieved by a magnetic flux through the ring. We find that a nonzero twist can improve communication through finite odd-numbered rings and enable high-fidelity multiparty quantum communication through spin rings (working near perfectly for rings of five and seven spins). We show that in certain cases, the twist results in the complete blockage of quantum-information flow to a certain site of the ring. This effect can be exploited to interface and entangle a flux qubit and a spin qubit without embedding the latter in a magnetic field

  7. An aeroelastic analysis of helicopter rotor blades incorporating piezoelectric fiber composite twist actuation

    Science.gov (United States)

    Wilkie, W. Keats; Park, K. C.

    1996-01-01

    A simple aeroelastic analysis of a helicopter rotor blade incorporating embedded piezoelectric fiber composite, interdigitated electrode blade twist actuators is described. The analysis consist of a linear torsion and flapwise bending model coupled with a nonlinear ONERA based unsteady aerodynamics model. A modified Galerkin procedure is performed upon the rotor blade partial differential equations of motion to develop a system of ordinary differential equations suitable for numerical integration. The twist actuation responses for three conceptual full-scale blade designs with realistic constraints on blade mass are numerically evaluated using the analysis. Numerical results indicate that useful amplitudes of nonresonant elastic twist, on the order of one to two degrees, are achievable under one-g hovering flight conditions for interdigitated electrode poling configurations. Twist actuation for the interdigitated electrode blades is also compared with the twist actuation of a conventionally poled piezoelectric fiber composite blade. Elastic twist produced using the interdigitated electrode actuators was found to be four to five times larger than that obtained with the conventionally poled actuators.

  8. Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis.

    Directory of Open Access Journals (Sweden)

    Phuoc T Tran

    Full Text Available KRAS mutant lung cancers are generally refractory to chemotherapy as well targeted agents. To date, the identification of drugs to therapeutically inhibit K-RAS have been unsuccessful, suggesting that other approaches are required. We demonstrate in both a novel transgenic mutant Kras lung cancer mouse model and in human lung tumors that the inhibition of Twist1 restores a senescence program inducing the loss of a neoplastic phenotype. The Twist1 gene encodes for a transcription factor that is essential during embryogenesis. Twist1 has been suggested to play an important role during tumor progression. However, there is no in vivo evidence that Twist1 plays a role in autochthonous tumorigenesis. Through two novel transgenic mouse models, we show that Twist1 cooperates with Kras(G12D to markedly accelerate lung tumorigenesis by abrogating cellular senescence programs and promoting the progression from benign adenomas to adenocarcinomas. Moreover, the suppression of Twist1 to physiological levels is sufficient to cause Kras mutant lung tumors to undergo senescence and lose their neoplastic features. Finally, we analyzed more than 500 human tumors to demonstrate that TWIST1 is frequently overexpressed in primary human lung tumors. The suppression of TWIST1 in human lung cancer cells also induced cellular senescence. Hence, TWIST1 is a critical regulator of cellular senescence programs, and the suppression of TWIST1 in human tumors may be an effective example of pro-senescence therapy.

  9. Geometrically exact nonlinear analysis of pre-twisted composite rotor blades

    Directory of Open Access Journals (Sweden)

    Li'na SHANG

    2018-02-01

    Full Text Available Modeling of pre-twisted composite rotor blades is very complicated not only because of the geometric non-linearity, but also because of the cross-sectional warping and the transverse shear deformation caused by the anisotropic material properties. In this paper, the geometrically exact nonlinear modeling of a generalized Timoshenko beam with arbitrary cross-sectional shape, generally anisotropic material behavior and large deflections has been presented based on Hodges’ method. The concept of decomposition of rotation tensor was used to express the strain in the beam. The variational asymptotic method was used to determine the arbitrary warping of the beam cross section. The generalized Timoshenko strain energy was derived from the equilibrium equations and the second-order asymptotically correct strain energy. The geometrically exact nonlinear equations of motion were established by Hamilton’s principle. The established modeling was used for the static and dynamic analysis of pre-twisted composite rotor blades, and the analytical results were validated based on experimental data. The influences of the transverse shear deformation on the pre-twisted composite rotor blade were investigated. The results indicate that the influences of the transverse shear deformation on the static deformation and the natural frequencies of the pre-twisted composite rotor blade are related to the length to chord ratio of the blade. Keywords: Geometrically exact, Nonlinear, Pre-twisted composite blade, Transverse shear deformation, Variational asymptotic, Warping

  10. A twisted flux-tube model for solar prominences. I. General properties

    International Nuclear Information System (INIS)

    Priest, E.R.; Hood, A.W.; Anzer, U.

    1989-01-01

    It is proposed that a solar prominence consists of cool plasma supported in a large-scale curved and twisted magnetic flux tube. As long as the flux tube is untwisted, its curvature is concave toward the solar surface, and so it cannot support dense plasma against gravity. However, when it is twisted sufficiently, individual field lines may acquire a convex curvature near their summits and so provide support. Cool plasma then naturally tends to accumulate in such field line dips either by injection from below or by thermal condensation. As the tube is twisted up further or reconnection takes place below the prominence, one finds a transition from normal to inverse polarity. When the flux tube becomes too long or is twisted too much, it loses stability and its true magnetic geometry as an erupting prominence is revealed more clearly. 56 refs

  11. Enhancement of heat transfer using varying width twisted tape inserts

    African Journals Online (AJOL)

    user

    enhancement of heat transfer with twisted tape inserts as compared to plain ... studies for heat transfer and pressure drop of laminar flow in horizontal tubes ... flow in rectangular and square plain ducts and ducts with twisted-tape inserts .... presence of the insert in the pipe causes resistance to flow and increases turbulence.

  12. Improved Reliability of Small Molecule Organic Solar Cells by Double Anode Buffer Layers

    Directory of Open Access Journals (Sweden)

    Pao-Hsun Huang

    2014-01-01

    Full Text Available An optimized hybrid planar heterojunction (PHJ of small molecule organic solar cells (SM-OSCs based on copper phthalocyanine (CuPc as donor and fullerene (C60 as acceptor was fabricated, which obviously enhanced the performance of device by sequentially using both MoO3 and pentacene as double anode buffer layers (ABL, also known as hole extraction layer (HEL. A series of the vacuum-deposited ABL, acting as an electron and exciton blocking layer, were examined for their characteristics in SM-OSCs. The performance and reliability were compared between conventional ITO/ABL/CuPc/C60/BCP/Ag cells and the new ITO/double ABL/CuPc/C60/BCP/Ag cells. The effect on the electrical properties of these materials was also investigated to obtain the optimal thickness of ABL. The comparison shows that the modified cell has an enhanced reliability compared to traditional cells. The improvement of lifetime was attributed to the idea of double layers to prevent humidity and oxygen from diffusing into the active layer. We demonstrated that the interfacial extraction layers are necessary to avoid degradation of device. That is to say, in normal temperature and pressure, a new avenue for the device within double buffer layers has exhibited the highest values of open circuit voltage (Voc, fill factor (FF, and lifetime in this work compared to monolayer of ABL.

  13. Gerbes over posets and twisted C*-dynamical systems

    OpenAIRE

    Vasselli, Ezio

    2017-01-01

    A base $\\Delta$ generating the topology of a space $M$ becomes a partially ordered set (poset), when ordered under inclusion of open subsets. Given a precosheaf over $\\Delta$ of fixed-point spaces (typically C*-algebras) under the action of a group $G$, in general one cannot find a precosheaf of $G$-spaces having it as fixed-point precosheaf. Rather one gets a gerbe over $\\Delta$, that is, a "twisted precosheaf" whose twisting is encoded by a cocycle with coefficients in a suitable 2-group. W...

  14. Factorising the 3D topologically twisted index

    Science.gov (United States)

    Cabo-Bizet, Alejandro

    2017-04-01

    We explore the path integration — upon the contour of hermitian (non-auxliary) field configurations — of topologically twisted N=2 Chern-Simons-matter theory (TTCSM) on {S}_2 times a segment. In this way, we obtain the formula for the 3D topologically twisted index, first as a convolution of TTCSM on {S}_2 times halves of {S}_1 , second as TTCSM on {S}_2 times {S}_1 — with a puncture, — and third as TTCSM on {S}_2× {S}_1 . In contradistinction to the first two cases, in the third case, the vector multiplet auxiliary field D is constrained to be anti-hermitian.

  15. Obstructions for twist star products

    Science.gov (United States)

    Bieliavsky, Pierre; Esposito, Chiara; Waldmann, Stefan; Weber, Thomas

    2018-05-01

    In this short note, we point out that not every star product is induced by a Drinfel'd twist by showing that not every Poisson structure is induced by a classical r-matrix. Examples include the higher genus symplectic Pretzel surfaces and the symplectic sphere S^2.

  16. Optics of twisted nematic and supertwisted nematic liquid-crystal displays

    Science.gov (United States)

    Leenhouts, F.; Schadt, M.

    1986-11-01

    For the first time calculations of the off-state transmission of twisted nematic liquid-crystal displays (LCD's) are presented which exhibit twist angles greater than the conventional 90 °. The transmission has been calculated using a treatment introduced by Priestley. In addition, the CIE (Commission Internationale d'Eclairage) color coordinates were evaluated which, together with the brightness, determine the optical appearance of an LCD. The finite efficiency of the polarizers was taken into account. The results are compared with those obtained for conventional 90 ° twisted nematic LCD's. From the calculations follow the conditions required to obtain optimal contrast and steep electro-optical characteristics in 180 ° supertwisted LCD's designed for high information content applications.

  17. miR-151-3p Targets TWIST1 to Repress Migration of Human Breast Cancer Cells.

    Directory of Open Access Journals (Sweden)

    Ting-Chih Yeh

    Full Text Available TWIST1 is a highly conserved basic helix-loop-helix transcription factor that contributes to cancer metastasis by promoting an epithelial-mesenchymal transition and repressing E-cadherin gene expression in breast cancer. In this study, we explored the potential role of miR-151 in TWIST1 expression and cancer properties in human breast cancer cells. We found that the human TWIST1 3'UTR contains a potential binging site for miR-151-3p at the putative target sequence 5'-CAGUCUAG-3'. Using a TWIST1-3'UTR luciferase reporter assay, we demonstrated that the target sequence within the TWIST1 3'UTR is required for miR-151-3p regulation of TWIST1 expression. Moreover, we found that ectopic expression of miR-151-3p by infection with adenoviruses expressing miR-151 significantly decreased TWIST1 expression, migration and invasion, but did not affect cell growth and tumorsphere formation of human breast cancer cells. In addition, overexpression of the protein coding region without the 3'UTR of TWIST1 reversed the repression of cell migration by miR-151-3p. Furthermore, knockdown of miR-151-3p increased TWIST1 expression, reduced E-cadherin expression, and enhanced cell migration. In conclusion, these results suggest that miR-151-3p directly regulates TWIST1 expression by targeting the TWIST1 3'UTR and thus repressing the migration and invasion of human breast cancer cells by enhancing E-cadherin expression. Our findings add to accumulating evidence that microRNAs are involved in breast cancer progression by modulating TWIST1 expression.

  18. PERFORMANCE CHARACTERISTICS OF PARABOLIC SOLAR COLLECTOR WATER HEATER SYSTEM FITTED WITH NAIL TWISTED TAPES ABSORBER

    Directory of Open Access Journals (Sweden)

    K. SYED JAFAR

    2017-03-01

    Full Text Available In this paper, the experimental heat transfer, friction loss and thermal performance data for water flowing through the absorber tube fitted with two different twisted tape configurations in parabolic trough collector (PTC are presented. In the present work, a relative experimental study is carried out to investigate the performance of a PTC influenced by heat transfer through fluidabsorber wall mixing mechanism. The major findings of this experiment show that heat transport enhancement in the nail twisted tape collector perform significantly better than plain twisted tapes and also show that the smallest twisted tape ratio enhances the system performance remarkably maximizing the collector efficiency. The results suggest that the twisted tape and nail twisted tape would be a better option for high thermal energy collection in laminar region of the PTC system.

  19. Spinning geometry = Twisted geometry

    International Nuclear Information System (INIS)

    Freidel, Laurent; Ziprick, Jonathan

    2014-01-01

    It is well known that the SU(2)-gauge invariant phase space of loop gravity can be represented in terms of twisted geometries. These are piecewise-linear-flat geometries obtained by gluing together polyhedra, but the resulting geometries are not continuous across the faces. Here we show that this phase space can also be represented by continuous, piecewise-flat three-geometries called spinning geometries. These are composed of metric-flat three-cells glued together consistently. The geometry of each cell and the manner in which they are glued is compatible with the choice of fluxes and holonomies. We first remark that the fluxes provide each edge with an angular momentum. By studying the piecewise-flat geometries which minimize edge lengths, we show that these angular momenta can be literally interpreted as the spin of the edges: the geometries of all edges are necessarily helices. We also show that the compatibility of the gluing maps with the holonomy data results in the same conclusion. This shows that a spinning geometry represents a way to glue together the three-cells of a twisted geometry to form a continuous geometry which represents a point in the loop gravity phase space. (paper)

  20. A New Twisting Somersault: 513XD

    Science.gov (United States)

    Tong, William; Dullin, Holger R.

    2017-12-01

    We present the mathematical framework of an athlete modelled as a system of coupled rigid bodies to simulate platform and springboard diving. Euler's equations of motion are generalised to non-rigid bodies and are then used to innovate a new dive sequence that in principle can be performed by real-world athletes. We begin by assuming that shape changes are instantaneous so that the equations of motion simplify enough to be solved analytically, and then use this insight to present a new dive (513XD) consisting of 1.5 somersaults and five twists using realistic shape changes. Finally, we demonstrate the phenomenon of converting pure somersaulting motion into pure twisting motion by using a sequence of impulsive shape changes, which may have applications in other fields such as space aeronautics.

  1. Hover Testing of the NASA/Army/MIT Active Twist Rotor Prototype Blade

    Science.gov (United States)

    Wilbur, Matthew L.; Yeager, William T., Jr.; Wilkie, W. Keats; Cesnik, Carlos E. S.; Shin, Sangloon

    2000-01-01

    Helicopter rotor individual blade control promises to provide a mechanism for increased rotor performance and reduced rotorcraft vibrations and noise. Active material methods, such as piezoelectrically actuated trailing-edge flaps and strain-induced rotor blade twisting, provide a means of accomplishing individual blade control without the need for hydraulic power in the rotating system. Recent studies have indicated that controlled strain induced blade twisting can be attained using piezoelectric active fiber composite technology. In order to validate these findings experimentally, a cooperative effort between NASA Langley Research Center, the Army Research Laboratory, and the MIT Active Materials and Structures Laboratory has been developed. As a result of this collaboration an aeroelastically-scaled active-twist model rotor blade has been designed and fabricated for testing in the heavy gas environment of the Langley Transonic Dynamics Tunnel (TDT). The results of hover tests of the active-twist prototype blade are presented in this paper. Comparisons with applicable analytical predictions of active-twist frequency response in hovering flight are also presented.

  2. From starproducts to Drinfeld-twists. Present and future applications

    International Nuclear Information System (INIS)

    Koch, Florian

    2008-01-01

    Physics comes up with models that invoke noncommutative structures in configuration space. Such structures are dual to the deformed coalgebra sector of a represented symmetry algebra. In the mean time such deformations are performed in terms of the symmetry algebra itself via twists or quasitriangular structures. One might thus find oneself in the bad situation that the symmetry algebra is not large enough to provide the required twist that dually matches the noncommutative structure found. It thus has to remain in the unpleasant state of being without any notion of symmetry. We show how starproducts can be pushed to twists by introducing a larger algebra that accommodates any finite dimensional representation of a Lie-algebra. This new algebra is similar to a Heisenberg-algebra but in contrast to the latter can be enhanced to a Hopf-algebra. Some Examples are given. (author)

  3. Anomalous phase shift in a twisted quantum loop

    International Nuclear Information System (INIS)

    Taira, Hisao; Shima, Hiroyuki

    2010-01-01

    The coherent motion of electrons in a twisted quantum ring is considered to explore the effect of torsion inherent to the ring. Internal torsion of the ring composed of helical atomic configuration yields a non-trivial quantum phase shift in the electrons' eigenstates. This torsion-induced phase shift causes novel kinds of persistent current flow and an Aharonov-Bohm-like conductance oscillation. The two phenomena can occur even when no magnetic flux penetrates inside the twisted ring, thus being in complete contrast with the counterparts observed in untwisted rings.

  4. Waveguides with asymptotically diverging twisting

    Czech Academy of Sciences Publication Activity Database

    Krejčiřík, David

    2015-01-01

    Roč. 46, AUG (2015), s. 7-10 ISSN 0893-9659 R&D Projects: GA ČR(CZ) GA14-06818S Institutional support: RVO:61389005 Keywords : quantum waveguide * exploding twisting * Quasi-bounded * Quasi-cylindrical * discrete spectrum Subject RIV: BE - Theoretical Physics Impact factor: 1.659, year: 2015

  5. Demonstration of an elastically coupled twist control concept for tilt rotor blade application

    Science.gov (United States)

    Lake, R. C.; Nixon, M. W.; Wilbur, M. L.; Singleton, J. D.; Mirick, P. H.

    1994-01-01

    The purpose of this Note is to present results from an analytic/experimental study that investigated the potential for passively changing blade twist through the use of extension-twist coupling. A set of composite model rotor blades was manufactured from existing blade molds for a low-twist metal helicopter rotor blade, with a view toward establishing a preliminary proof concept for extension-twist-coupled rotor blades. Data were obtained in hover for both a ballasted and unballasted blade configuration in sea-level atmospheric conditions. Test data were compared with results obtained from a geometrically nonlinear analysis of a detailed finite element model of the rotor blade developed in MSC/NASTRAN.

  6. Particle image velocimetry measurements of 2-dimensional velocity field around twisted tape

    Energy Technology Data Exchange (ETDEWEB)

    Song, Min Seop; Park, So Hyun; Kim, Eung Soo, E-mail: kes7741@snu.ac.kr

    2016-11-01

    Highlights: • Measurements of the flow field in a pipe with twisted tape were conducted by particle image velocimetry (PIV). • A novel matching index of refraction technique utilizing 3D printing and oil mixture was adopted to make the test section transparent. • Undistorted particle images were clearly captured in the presence of twisted tape. • 2D flow field in the pipe with twisted tape revealed the characteristic two-peak velocity profile. - Abstract: Twisted tape is a passive component used to enhance heat exchange in various devices. It induces swirl flow that increases the mixing of fluid. Thus, ITER selected the twisted tape as one of the candidates for turbulence promoting in the divertor cooling. Previous study was mainly focused on the thermohydraulic performance of the twisted tape. As detailed data on the velocity field around the twisted tape was insufficient, flow visualization study was performed to provide fundamental data on velocity field. To visualize the flow in a complex structure, novel matching index of refraction technique was used with 3-D printing and mixture of anise and mineral oil. This technique enables the camera to capture undistorted particle image for velocity field measurement. Velocity fields at Reynolds number 1370–9591 for 3 different measurement plane were obtained through particle image velocimetry. The 2-dimensional averaged velocity field data were obtained from 177 pair of instantaneous velocity fields. It reveals the characteristic two-peak flow motion in axial direction. In addition, the normalized velocity profiles were converged with increase of Reynolds numbers. Finally, the uncertainty of the result data was analyzed.

  7. Epigenetic inactivation of TWIST2 in acute lymphoblastic leukemia modulates proliferation, cell survival and chemosensitivity

    Science.gov (United States)

    Thathia, Shabnam H.; Ferguson, Stuart; Gautrey, Hannah E.; van Otterdijk, Sanne D.; Hili, Michela; Rand, Vikki; Moorman, Anthony V.; Meyer, Stefan; Brown, Robert; Strathdee, Gordon

    2012-01-01

    Background Altered regulation of many transcription factors has been shown to be important in the development of leukemia. TWIST2 modulates the activity of a number of important transcription factors and is known to be a regulator of hematopoietic differentiation. Here, we investigated the significance of epigenetic regulation of TWIST2 in the control of cell growth and survival and in response to cytotoxic agents in acute lymphoblastic leukemia. Design and Methods TWIST2 promoter methylation status was assessed quantitatively, by combined bisulfite and restriction analysis (COBRA) and pyrosequencing assays, in multiple types of leukemia and TWIST2 expression was determined by quantitative reverse transcriptase polymerase chain reaction analysis. The functional role of TWIST2 in cell proliferation, survival and response to chemotherapy was assessed in transient and stable expression systems. Results We found that TWIST2 was inactivated in more than 50% of cases of childhood and adult acute lymphoblastic leukemia through promoter hypermethylation and that this epigenetic regulation was especially prevalent in RUNX1-ETV6-driven cases. Re-expression of TWIST2 in cell lines resulted in a dramatic reduction in cell growth and induction of apoptosis in the Reh cell line. Furthermore, re-expression of TWIST2 resulted in increased sensitivity to the chemotherapeutic agents etoposide, daunorubicin and dexamethasone and TWIST2 hypermethylation was almost invariably found in relapsed adult acute lymphoblastic leukemia (91% of samples hypermethylated). Conclusions This study suggests a dual role for epigenetic inactivation of TWIST2 in acute lymphoblastic leukemia, initially through altering cell growth and survival properties and subsequently by increasing resistance to chemotherapy. PMID:22058208

  8. Numerical Modeling of Pump Absorption in Coiled and Twisted Double-Clad Fibers

    Czech Academy of Sciences Publication Activity Database

    Koška, Pavel; Peterka, Pavel; Doya, V.

    2016-01-01

    Roč. 22, č. 2 (2016), s. 4401508 ISSN 1077-260X R&D Projects: GA ČR GA14-35256S; GA MŠk(CZ) LD15122 Institutional support: RVO:67985882 Keywords : double-clad optical fibers * beam propagation method * fiber amplifiers Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 3.971, year: 2016

  9. Modal Properties and Stability of Bend-Twist Coupled Wind Turbine Blades

    DEFF Research Database (Denmark)

    Stäblein, Alexander R.; Hansen, Morten Hartvig; Verelst, David Robert

    2017-01-01

    a steady-state equilibrium using the aero-servo-elastic tool HAWCStab2 which has been extended by a beam element that allows for fully coupled cross-sectional properties. Bend-twist coupling is introduced in the cross-sectional stiffness matrix by means of coupling coefficients that introduce twist...

  10. Study of Implosion of Twisted Nested Arrays at the Angara-5-1 Facility

    Science.gov (United States)

    Mitrofanov, K. N.; Zukakishvili, G. G.; Aleksandrov, V. V.; Grabovski, E. V.; Frolov, I. N.; Gribov, A. N.

    2018-01-01

    Results are presented from experimental studies of the implosion of twisted nested arrays in which the wires of the outer and inner arrays are twisted about the array axis in opposite directions (clockwise and counterclockwise). Experiments with twisted arrays were carried out at the Angara-5-1 facility at currents of up to 4 MA. The currents through the arrays were switched either simultaneously or the current pulse through the outer array was delayed by 10-15 ns with the help of an anode spark gap. It is shown that, in such arrays, the currents flow along the inclined wires and, accordingly, there are both the azimuthal and axial components of the discharge current. The process of plasma implosion in twisted arrays depends substantially on the value of the axial (longitudinal) magnetic field generated inside the array by the azimuthal currents. Two-dimensional simulations of the magnetic field in twisted nested arrays were performed in the ( r, z) geometry with allowance for the skin effect in the discharge electrodes. It is shown that, depending on the geometry of the discharge electrodes, different configurations of the magnetic field can be implemented inside twisted nested arrays. The calculated magnetic configurations are compared with the results of measurements of the magnetic field inside such arrays. It is shown that the configuration of the axial magnetic field inside a twisted nested array depends substantially on the distribution of the azimuthal currents between the inner and outer arrays.

  11. Realizations of κ-Minkowski space, Drinfeld twists, and related symmetry algebras

    Energy Technology Data Exchange (ETDEWEB)

    Juric, Tajron; Meljanac, Stjepan; Pikutic, Danijel [Ruder Boskovic Institute, Theoretical Physics Division, Zagreb (Croatia)

    2015-11-15

    Realizations of κ-Minkowski space linear in momenta are studied for time-, space- and light-like deformations. We construct and classify all such linear realizations and express them in terms of the gl(n) generators. There are three one-parameter families of linear realizations for timelike and space-like deformations, while for light-like deformations, there are only four linear realizations. The relation between a deformed Heisenberg algebra, the star product, the coproduct of momenta, and the twist operator is presented. It is proved that for each linear realization there exists a Drinfeld twist satisfying normalization and cocycle conditions. κ-Deformed igl(n)-Hopf algebras are presented for all cases. The κ-Poincare-Weyl and κ-Poincare-Hopf algebras are discussed. The left-right dual κ-Minkowski algebra is constructed from the transposed twists. The corresponding realizations are nonlinear. All Drinfeld twists related to κ-Minkowski space are obtained from our construction. Finally, some physical applications are discussed. (orig.)

  12. Realizations of κ-Minkowski space, Drinfeld twists, and related symmetry algebras

    International Nuclear Information System (INIS)

    Juric, Tajron; Meljanac, Stjepan; Pikutic, Danijel

    2015-01-01

    Realizations of κ-Minkowski space linear in momenta are studied for time-, space- and light-like deformations. We construct and classify all such linear realizations and express them in terms of the gl(n) generators. There are three one-parameter families of linear realizations for timelike and space-like deformations, while for light-like deformations, there are only four linear realizations. The relation between a deformed Heisenberg algebra, the star product, the coproduct of momenta, and the twist operator is presented. It is proved that for each linear realization there exists a Drinfeld twist satisfying normalization and cocycle conditions. κ-Deformed igl(n)-Hopf algebras are presented for all cases. The κ-Poincare-Weyl and κ-Poincare-Hopf algebras are discussed. The left-right dual κ-Minkowski algebra is constructed from the transposed twists. The corresponding realizations are nonlinear. All Drinfeld twists related to κ-Minkowski space are obtained from our construction. Finally, some physical applications are discussed. (orig.)

  13. Automatic O(a) improvement for twisted mass QCD in the presence of spontaneous symmetry breaking

    International Nuclear Information System (INIS)

    Aoki, Sinya; Baer, Oliver

    2006-01-01

    In this paper we present a proof for automatic O(a) improvement in twisted mass lattice QCD at maximal twist, which uses only the symmetries of the leading part in the Symanzik effective action. In the process of the proof we clarify that the twist angle is dynamically determined by vacuum expectation values in the Symanzik theory. For maximal twist according to this definition, we show that scaling violations of all quantities which have nonzero values in the continuum limit are even in a. In addition, using Wilson chiral perturbation theory, we investigate this definition for maximal twist and compare it to other definitions which were already employed in actual simulations

  14. The $SU(\\infty)$ twisted gradient flow running coupling

    CERN Document Server

    Pérez, Margarita García; Keegan, Liam; Okawa, Masanori

    2015-01-01

    We measure the running of the $SU(\\infty)$ 't Hooft coupling by performing a step scaling analysis of the Twisted Eguchi-Kawai (TEK) model, the SU($N$) gauge theory on a single site lattice with twisted boundary conditions. The computation relies on the conjecture that finite volume effects for SU(N) gauge theories defined on a 4-dimensional twisted torus are controlled by an effective size parameter $\\tilde l = l \\sqrt{N}$, with $l$ the torus period. We set the scale for the running coupling in terms of $\\tilde l$ and use the gradient flow to define a renormalized 't Hooft coupling $\\lambda(\\tilde l)$. In the TEK model, this idea allows the determination of the running of the coupling through a step scaling procedure that uses the rank of the group as a size parameter. The continuum renormalized coupling constant is extracted in the zero lattice spacing limit, which in the TEK model corresponds to the large $N$ limit taken at fixed value of $\\lambda(\\tilde l)$. The coupling constant is thus expected to coinc...

  15. Twist effects in quantum vortices and phase defects

    Science.gov (United States)

    Zuccher, Simone; Ricca, Renzo L.

    2018-02-01

    In this paper we show that twist, defined in terms of rotation of the phase associated with quantum vortices and other physical defects effectively deprived of internal structure, is a property that has observable effects in terms of induced axial flow. For this we consider quantum vortices governed by the Gross-Pitaevskii equation (GPE) and perform a number of test cases to investigate and compare the effects of twist in two different contexts: (i) when this is artificially superimposed on an initially untwisted vortex ring; (ii) when it is naturally produced on the ring by the simultaneous presence of a central straight vortex. In the first case large amplitude perturbations quickly develop, generated by the unnatural setting of the initial condition that is not an analytical solution of the GPE. In the second case much milder perturbations emerge, signature of a genuine physical process. This scenario is confirmed by other test cases performed at higher twist values. Since the second setting corresponds to essential linking, these results provide new evidence of the influence of topology on physics.

  16. Factorising the 3D topologically twisted index

    Energy Technology Data Exchange (ETDEWEB)

    Cabo-Bizet, Alejandro [Instituto de Astronomía y Física del Espacio (CONICET-UBA),Ciudad Universitaria, C.P. 1428, Buenos Aires (Argentina)

    2017-04-20

    We explore the path integration — upon the contour of hermitian (non-auxliary) field configurations — of topologically twisted N=2 Chern-Simons-matter theory (TTCSM) on S{sub 2} times a segment. In this way, we obtain the formula for the 3D topologically twisted index, first as a convolution of TTCSM on S{sub 2} times halves of S{sub 1}, second as TTCSM on S{sub 2} times S{sub 1} — with a puncture, — and third as TTCSM on S{sub 2}×S{sub 1}. In contradistinction to the first two cases, in the third case, the vector multiplet auxiliary field D is constrained to be anti-hermitian.

  17. Leibniz algebroids, twistings and exceptional generalized geometry

    Science.gov (United States)

    Baraglia, D.

    2012-05-01

    We investigate a class of Leibniz algebroids which are invariant under diffeomorphisms and symmetries involving collections of closed forms. Under appropriate assumptions we arrive at a classification which in particular gives a construction starting from graded Lie algebras. In this case the Leibniz bracket is a derived bracket and there are higher derived brackets resulting in an L∞-structure. The algebroids can be twisted by a non-abelian cohomology class and we prove that the twisting class is described by a Maurer-Cartan equation. For compact manifolds we construct a Kuranishi moduli space of this equation which is shown to be affine algebraic. We explain how these results are related to exceptional generalized geometry.

  18. On the twists of interplanetary magnetic flux ropes observed at 1 AU

    OpenAIRE

    Wang, Yuming; Zhuang, Bin; Hu, Qiang; Liu, Rui; Shen, Chenglong; Chi, Yutian

    2016-01-01

    Magnetic flux ropes (MFRs) are one kind of fundamental structures in the solar physics, and involved in various eruption phenomena. Twist, characterizing how the magnetic field lines wind around a main axis, is an intrinsic property of MFRs, closely related to the magnetic free energy and stableness. So far it is unclear how much amount of twist is carried by MFRs in the solar atmosphere and in heliosphere and what role the twist played in the eruptions of MFRs. Contrasting to the solar MFRs,...

  19. Exclusive processes beyond leading twist: {gamma}*T {yields} {rho}T impact factor with twist three accuracy

    Energy Technology Data Exchange (ETDEWEB)

    Szymanowski, Lech [Soltan Institute for Nuclear Studies, Hoza 69, 00691, Warsaw (Poland); Anikin, Igor V. [Joint Institute for Nuclear Research - JINR, Joliot-Curie st., 6, Moskovskaya obl., 141980, Dubna (Russian Federation); Ivanov, Dmitry Yu [Sobolev Institute of Mathematics, Acad. Koptyug pr., 4, 630090 Novosibirsk (Russian Federation); Pire, Bernard [Centre de Physique Theorique - CPHT, UMR 7644, Ecole Polytechnique, Bat. 6, RDC, F91128 Palaiseau Cedex (France); Wallon, Samuel [Laboratoire de Physique Theorique d' Orsay - LPT, Bat. 210, Univ. Paris-Sud 11, 91405 Orsay Cedex (France)

    2010-07-01

    We describe a consistent approach to factorization of scattering amplitudes for exclusive processes beyond the leading twist approximation. The method is based on the Taylor expansion of the scattering amplitude in the momentum space around the dominant light-cone direction and thus naturally introduces an appropriate set of non-perturbative correlators which encode effects not only of the lowest but also of the higher Fock states of the produced particle. The reduction of original set of correlators to a set of independent ones is achieved with the help of equations of motion and invariance of the scattering amplitude under rotation on the light-cone. As a concrete application, we compute the expressions of the impact factor for the transition of virtual photon to transversally polarised {rho}-meson up to the twist 3 accuracy. (Phys.Lett.B682:413-418,2010 and Nucl.Phys.B828:1-68,2010.). (authors)

  20. Inner Surface Chirality of Single-Handed Twisted Carbonaceous Tubular Nanoribbons.

    Science.gov (United States)

    Liu, Dan; Li, Baozong; Guo, Yongmin; Li, Yi; Yang, Yonggang

    2015-11-01

    Single-handed twisted 4,4'-biphenylene-bridged polybissilsesquioxane tubular nanoribbons and single-layered nanoribbons were prepared by tuning the water/ethanol volume ratio in the reaction mixture at pH = 11.6 through a supramolecular templating approach. The single-layered nanoribbons were formed by shrinking tubular nanoribbons after the removal of the templates. In addition, solvent-induced handedness inversion was achieved. The handedness of the polybissilsesquioxanes could be controlled by changing the ethanol/water volume ratio in the reaction mixture. After carbonization at 900 °C for 4.0 h and removal of silica, single-handed twisted carbonaceous tubular nanoribbons and single-layered nanoribbons with micropores in the walls were obtained. X-ray diffraction and Raman spectroscopy analyses indicated that the carbon is predominantly amorphous. The circular dichroism spectra show that the twisted tubular nanoribbons exhibit optical activity, while the twisted single-layered nanoribbons do not. The results shown here indicate that chirality is transferred from the organic self-assemblies to the inner surfaces of the 4,4'-biphenylene-bridged polybissilsesquioxane tubular nanoribbons and subsequently to those of the carbonaceous tubular nanoribbons. © 2015 Wiley Periodicals, Inc.

  1. Osserman and conformally Osserman manifolds with warped and twisted product structure

    OpenAIRE

    Brozos-Vazquez, M.; Garcia-Rio, E.; Vazquez-Lorenzo, R.

    2008-01-01

    We characterize Osserman and conformally Osserman Riemannian manifolds with the local structure of a warped product. By means of this approach we analyze the twisted product structure and obtain, as a consequence, that the only Osserman manifolds which can be written as a twisted product are those of constant curvature.

  2. An improved hazard rate twisting approach for the statistic of the sum of subexponential variates

    KAUST Repository

    Rached, Nadhir B.; Kammoun, Abla; Alouini, Mohamed-Slim; Tempone, Raul

    2015-01-01

    In this letter, we present an improved hazard rate twisting technique for the estimation of the probability that a sum of independent but not necessarily identically distributed subexponential Random Variables (RVs) exceeds a given threshold. Instead of twisting all the components in the summation, we propose to twist only the RVs which have the biggest impact on the right-tail of the sum distribution and keep the other RVs unchanged. A minmax approach is performed to determine the optimal twisting parameter which leads to an asymptotic optimality criterion. Moreover, we show through some selected simulation results that our proposed approach results in a variance reduction compared to the technique where all the components are twisted.

  3. ELIPGRID-PC: Upgraded version

    International Nuclear Information System (INIS)

    Davidson, J.R.

    1995-12-01

    Evaluating the need for and the effectiveness of remedial cleanup at waste sites often includes finding average contaminant concentrations and identifying pockets of contamination called hot spots. The standard tool for calculating the probability of detecting pockets of contamination called hot spots has been the ELIPGRID code of singer and Wickman. The ELIPGRID-PC program has recently made this algorithm available for an IBM reg-sign personal computer (PC) or compatible. A new version of ELIPGRID-PC, incorporating Monte Carlo test results and simple graphics, is herein described. Various examples of how to use the program for both single and multiple hot spot cases are given. The code for an American National Standards Institute C version of the ELIPGRID algorithm is provided, and limitations and further work are noted. This version of ELIPGRID-PC reliably meets the goal of moving Singer's ELIPGRID algorithm to the PC

  4. Effect of Magnetic Twist on Nonlinear Transverse Kink Oscillations of Line-tied Magnetic Flux Tubes

    Science.gov (United States)

    Terradas, J.; Magyar, N.; Van Doorsselaere, T.

    2018-01-01

    Magnetic twist is thought to play an important role in many structures of the solar atmosphere. One of the effects of twist is to modify the properties of the eigenmodes of magnetic tubes. In the linear regime standing kink solutions are characterized by a change in polarization of the transverse displacement along the twisted tube. In the nonlinear regime, magnetic twist affects the development of shear instabilities that appear at the tube boundary when it is oscillating laterally. These Kelvin–Helmholtz instabilities (KHI) are produced either by the jump in the azimuthal component of the velocity at the edge of the sharp boundary between the internal and external part of the tube or by the continuous small length scales produced by phase mixing when there is a smooth inhomogeneous layer. In this work the effect of twist is consistently investigated by solving the time-dependent problem including the process of energy transfer to the inhomogeneous layer. It is found that twist always delays the appearance of the shear instability, but for tubes with thin inhomogeneous layers the effect is relatively small for moderate values of twist. On the contrary, for tubes with thick layers, the effect of twist is much stronger. This can have some important implications regarding observations of transverse kink modes and the KHI itself.

  5. Designing an artificial neural network using radial basis function to model exergetic efficiency of nanofluids in mini double pipe heat exchanger

    Science.gov (United States)

    Ghasemi, Nahid; Aghayari, Reza; Maddah, Heydar

    2018-06-01

    The present study aims at predicting and optimizing exergetic efficiency of TiO2-Al2O3/water nanofluid at different Reynolds numbers, volume fractions and twisted ratios using Artificial Neural Networks (ANN) and experimental data. Central Composite Design (CCD) and cascade Radial Basis Function (RBF) were used to display the significant levels of the analyzed factors on the exergetic efficiency. The size of TiO2-Al2O3/water nanocomposite was 20-70 nm. The parameters of ANN model were adapted by a training algorithm of radial basis function (RBF) with a wide range of experimental data set. Total mean square error and correlation coefficient were used to evaluate the results which the best result was obtained from double layer perceptron neural network with 30 neurons in which total Mean Square Error(MSE) and correlation coefficient (R2) were equal to 0.002 and 0.999, respectively. This indicated successful prediction of the network. Moreover, the proposed equation for predicting exergetic efficiency was extremely successful. According to the optimal curves, the optimum designing parameters of double pipe heat exchanger with inner twisted tape and nanofluid under the constrains of exergetic efficiency 0.937 are found to be Reynolds number 2500, twisted ratio 2.5 and volume fraction( v/v%) 0.05.

  6. Fast Torsional Artificial Muscles from NiTi Twisted Yarns.

    Science.gov (United States)

    Mirvakili, Seyed M; Hunter, Ian W

    2017-05-17

    Torsional artificial muscles made of multiwalled carbon nanotube/niobium nanowire yarns have shown remarkable torsional speed and gravimetric torque. The muscle structure consists of a twisted yarn with half of its length infiltrated with a stimuli-responsive guest material such as paraffin wax. The volumetric expansion of the guest material creates the torsional actuation in the yarn. In the present work, we show that this type of actuation is not unique to wax-infiltrated carbon multiwalled nanotube (MWCNT) or niobium nanowire yarns and that twisted yarn of NiTi alloy fibers also produces fast torsional actuation. By gold-plating half the length of a NiTi twisted yarn and Joule heating it, we achieved a fully reversible torsional actuation of up to 16°/mm with peak torsional speed of 10 500 rpm and gravimetric torque of 8 N·m/kg. These results favorably compare to those of MWCNTs and niobium nanowire yarns.

  7. Twisted vertex algebras, bicharacter construction and boson-fermion correspondences

    International Nuclear Information System (INIS)

    Anguelova, Iana I.

    2013-01-01

    The boson-fermion correspondences are an important phenomena on the intersection of several areas in mathematical physics: representation theory, vertex algebras and conformal field theory, integrable systems, number theory, cohomology. Two such correspondences are well known: the types A and B (and their super extensions). As a main result of this paper we present a new boson-fermion correspondence of type D-A. Further, we define a new concept of twisted vertex algebra of order N, which generalizes super vertex algebra. We develop the bicharacter construction which we use for constructing classes of examples of twisted vertex algebras, as well as for deriving formulas for the operator product expansions, analytic continuations, and normal ordered products. By using the underlying Hopf algebra structure we prove general bicharacter formulas for the vacuum expectation values for two important groups of examples. We show that the correspondences of types B, C, and D-A are isomorphisms of twisted vertex algebras

  8. Probing the interlayer coupling of twisted bilayer MoS2 using photoluminescence spectroscopy.

    Science.gov (United States)

    Huang, Shengxi; Ling, Xi; Liang, Liangbo; Kong, Jing; Terrones, Humberto; Meunier, Vincent; Dresselhaus, Mildred S

    2014-10-08

    Two-dimensional molybdenum disulfide (MoS2) is a promising material for optoelectronic devices due to its strong photoluminescence emission. In this work, the photoluminescence of twisted bilayer MoS2 is investigated, revealing a tunability of the interlayer coupling of bilayer MoS2. It is found that the photoluminescence intensity ratio of the trion and exciton reaches its maximum value for the twisted angle 0° or 60°, while for the twisted angle 30° or 90° the situation is the opposite. This is mainly attributed to the change of the trion binding energy. The first-principles density functional theory analysis further confirms the change of the interlayer coupling with the twisted angle, which interprets our experimental results.

  9. Light hadrons from Nf=2+1+1 dynamical twisted mass fermions

    NARCIS (Netherlands)

    Baron, R.; Blossier, B.; Boucaud, P.; Carbonell, J.; Deuzeman, A.; Drach, V.; Farchioni, F.; Gimenez, V.; Herdoiza, G.; Jansen, K.; Michael, C.; Montvay, I.; Pallante, E.; Pène, O.; Reker, S.; Urbach, C.; Wagner, M.; Wenger, U.; Collaboration, for the ETM

    2011-01-01

    We present results of lattice QCD simulations with mass-degenerate up and down and mass-split strange and charm (Nf=2+1+1) dynamical quarks using Wilson twisted mass fermions at maximal twist. The tuning of the strange and charm quark masses is performed at three values of the lattice spacing a~0.06

  10. On the Compton Twist-3 Asymmetries

    International Nuclear Information System (INIS)

    Korotkiyan, V.M.; Teryaev, O.V.

    1994-01-01

    The 'fermionic poles' contribution to the twist-3 single asymmetry in the gluon Compton process is calculated. The 'gluonic poles' existence seems to contradict the density matrix positivity. Qualitative predictions for the direct photon and jets asymmetries are presented. 13 refs., 2 figs

  11. TWIST1 a new determinant of epithelial to mesenchymal transition in EGFR mutated lung adenocarcinoma.

    Directory of Open Access Journals (Sweden)

    Karine Pallier

    Full Text Available Metastasis is a multistep process and the main cause of mortality in lung cancer patients. We previously showed that EGFR mutations were associated with a copy number gain at a locus encompassing the TWIST1 gene on chromosome 7. TWIST1 is a highly conserved developmental gene involved in embryogenesis that may be reactivated in cancers promoting both malignant conversion and cancer progression through an epithelial to mesenchymal transition (EMT. The aim of this study was to investigate the possible implication of TWIST1 reactivation on the acquisition of a mesenchymal phenotype in EGFR mutated lung cancer. We studied a series of consecutive lung adenocarcinoma from Caucasian non-smokers for which surgical frozen samples were available (n = 33 and showed that TWIST1 expression was linked to EGFR mutations (P<0.001, to low CDH1 expression (P<0.05 and low disease free survival (P = 0.044. To validate that TWIST1 is a driver of EMT in EGFR mutated lung cancer, we used five human lung cancer cell lines and demonstrated that EMT and the associated cell mobility were dependent upon TWIST1 expression in cells with EGFR mutation. Moreover a decrease of EGFR pathway stimulation through EGF retrieval or an inhibition of TWIST1 expression by small RNA technology reversed the phenomenon. Collectively, our in vivo and in vitro findings support that TWIST1 collaborates with the EGF pathway in promoting EMT in EGFR mutated lung adenocarcinoma and that large series of EGFR mutated lung cancer patients are needed to further define the prognostic role of TWIST1 reactivation in this subgroup.

  12. Study of twist boundaries in aluminium. Structure and intergranular diffusion

    International Nuclear Information System (INIS)

    Lemuet, Daniel

    1981-01-01

    This research thesis addresses the study of grain boundaries in oriented crystals, and more particularly the systematic calculation of intergranular structures and energies of twist boundaries of <001> axis in aluminium, the determination of intergranular diffusion coefficients of zinc in a set of twist bi-crystals of same axis encompassing a whole range of disorientations, and the search for a correlation between these experimental results and calculated structures

  13. High performance twisted and coiled soft actuator with spandex fiber for artificial muscles

    Science.gov (United States)

    Yang, Sang Yul; Cho, Kyeong Ho; Kim, Youngeun; Song, Min-Geun; Jung, Ho Sang; Yoo, Ji Wang; Moon, Hyungpil; Koo, Ja Choon; Nam, Jae-do; Ryeol Choi, Hyouk

    2017-10-01

    This paper reports the twisted and coiled soft actuator (abbreviated with STCA) with spandex fiber. The STCA exhibits higher actuation strain at lower temperature than the previous nylon twisted and coiled soft actuators (abbreviated with NTCAs). While NTCAs are fabricated using a twist-insertion process until coils are formed, a new method is developed to fabricate the STCA using the ultra-stretch of spandex, whereby the STCA is twisted again after the coil has been formed. A 6-gear-twist-insertion device that increases the stability and the fabrication speed is developed to fabricate the STCA. The superior performance exhibited by the STCA is due to the 14% contraction strain of the bare spandex (bare nylon: 4%) and the low spring constant of 0.0115 N mm-1. The maximum tensile actuation strain of STCA was 45% at 130 °C, and the maximum specific work was 1.523 kJ kg-1 at 130 °C. STCA could repeatedly actuate 100 times with a strain change of less than 0.4%.

  14. IRONY IN CHARLES DICKEN'S OLIVER TWIST

    Directory of Open Access Journals (Sweden)

    Ika Kana Trisnawati

    2016-05-01

    Full Text Available This paper describes the types of irony used by Charles Dickens in his notable early work, Oliver Twist, as well as the reasons the irony was chosen. As a figurative language, irony is utilized to express one’s complex feelings without truly saying them. In Oliver Twist, Dickens brought the readers some real social issues wrapped in dark, deep written expressions of irony uttered by the characters of his novel. Undoubtedly, the novel had left an impact to the British society at the time. The irony Dickens displayed here includes verbal, situational, and dramatic irony. His choice of irony made sense as he intended to criticize the English Poor Laws and to touch the public sentiment. He wanted to let the readers go beyond what was literally written and once they discovered what the truth was, they would eventually understand Dickens’ purposes.

  15. Twist1 Controls a Cell-Specification Switch Governing Cell Fate Decisions within the Cardiac Neural Crest

    Science.gov (United States)

    Vincentz, Joshua W.; Firulli, Beth A.; Lin, Andrea; Spicer, Douglas B.; Howard, Marthe J.; Firulli, Anthony B.

    2013-01-01

    Neural crest cells are multipotent progenitor cells that can generate both ectodermal cell types, such as neurons, and mesodermal cell types, such as smooth muscle. The mechanisms controlling this cell fate choice are not known. The basic Helix-loop-Helix (bHLH) transcription factor Twist1 is expressed throughout the migratory and post-migratory cardiac neural crest. Twist1 ablation or mutation of the Twist-box causes differentiation of ectopic neuronal cells, which molecularly resemble sympathetic ganglia, in the cardiac outflow tract. Twist1 interacts with the pro-neural factor Sox10 via its Twist-box domain and binds to the Phox2b promoter to repress transcriptional activity. Mesodermal cardiac neural crest trans-differentiation into ectodermal sympathetic ganglia-like neurons is dependent upon Phox2b function. Ectopic Twist1 expression in neural crest precursors disrupts sympathetic neurogenesis. These data demonstrate that Twist1 functions in post-migratory neural crest cells to repress pro-neural factors and thereby regulate cell fate determination between ectodermal and mesodermal lineages. PMID:23555309

  16. Higher twist effects in QCD description of light meson exclusive formfactors

    International Nuclear Information System (INIS)

    Gorskij, A.S.

    1987-01-01

    The general approach to a quantitative description of higher twist effects in hard exclusive processes in QCD is proposed. The consistent calculations in coordinate space and the choice of special gauges for quantum and classical gluon fields are essential ingradients of this method. The self consistent system of twist three wave functions for π-meson has been built

  17. Peak Pc Prediction in Conjunction Analysis: Conjunction Assessment Risk Analysis. Pc Behavior Prediction Models

    Science.gov (United States)

    Vallejo, J.J.; Hejduk, M.D.; Stamey, J. D.

    2015-01-01

    Satellite conjunction risk typically evaluated through the probability of collision (Pc). Considers both conjunction geometry and uncertainties in both state estimates. Conjunction events initially discovered through Joint Space Operations Center (JSpOC) screenings, usually seven days before Time of Closest Approach (TCA). However, JSpOC continues to track objects and issue conjunction updates. Changes in state estimate and reduced propagation time cause Pc to change as event develops. These changes a combination of potentially predictable development and unpredictable changes in state estimate covariance. Operationally useful datum: the peak Pc. If it can reasonably be inferred that the peak Pc value has passed, then risk assessment can be conducted against this peak value. If this value is below remediation level, then event intensity can be relaxed. Can the peak Pc location be reasonably predicted?

  18. Fiber-Optic Sensors for Measurements of Torsion, Twist and Rotation: A Review.

    Science.gov (United States)

    Budinski, Vedran; Donlagic, Denis

    2017-02-23

    Optical measurement of mechanical parameters is gaining significant commercial interest in different industry sectors. Torsion, twist and rotation are among the very frequently measured mechanical parameters. Recently, twist/torsion/rotation sensors have become a topic of intense fiber-optic sensor research. Various sensing concepts have been reported. Many of those have different properties and performances, and many of them still need to be proven in out-of-the laboratory use. This paper provides an overview of basic approaches and a review of current state-of-the-art in fiber optic sensors for measurements of torsion, twist and/or rotation.Invited Paper.

  19. Resveratrol Protects PC12 Cell against 6-OHDA Damage via CXCR4 Signaling Pathway

    Directory of Open Access Journals (Sweden)

    Jing Zhang

    2015-01-01

    Full Text Available Resveratrol, herbal nonflavonoid polyphenolic compound naturally derived from grapes, has long been acknowledged to possess extensive biological and pharmacological properties including antioxidant and anti-inflammatory ones and may exert a neuroprotective effect on neuronal damage in neurodegenerative diseases. However, the underlying molecular mechanisms remain undefined. In the present study, we intended to investigate the neuroprotective effects of resveratrol against 6-OHDA-induced neurotoxicity of PC12 cells and further explore the possible mechanisms involved. For this purpose, PC12 cells were exposed to 6-OHDA in the presence of resveratrol (0, 12.5, 25, and 50 μM. The results showed that resveratrol increased cell viability, alleviated the MMP reduction, and reduced the number of apoptotic cells as measured by MTT assay, JC-1 staining, and Hoechst/PI double staining (all p<0.01. Immunofluorescent staining and Western blotting revealed that resveratrol averts 6-OHDA induced CXCR4 upregulation (p<0.01. Our results demonstrated that resveratrol could effectively protect PC12 cells from 6-OHDA-induced oxidative stress and apoptosis via CXCR4 signaling pathway.

  20. Stability of short wavelength tearing and twisting modes

    International Nuclear Information System (INIS)

    Waelbroeck, F.L.

    1998-01-01

    The stability and mutual interaction of tearing and twisting modes in a torus is governed by matrices that generalize the well-known Δ' stability index. The diagonal elements of these matrices determine the intrinsic stability of modes that reconnect the magnetic field at a single resonant surface. The off-diagonal elements indicate the strength of the coupling between the different modes. The author shows how the elements of these matrices can be evaluated, in the limit of short wavelength, from the free energy driving radially extended ballooning modes. The author applies the results by calculating the tearing and twisting Δ' for a model high-beta equilibrium with circular flux surfaces

  1. Twist deformations leading to κ-Poincaré Hopf algebra and their application to physics

    International Nuclear Information System (INIS)

    Jurić, Tajron; Meljanac, Stjepan; Samsarov, Andjelo

    2016-01-01

    We consider two twist operators that lead to kappa-Poincaré Hopf algebra, the first being an Abelian one and the second corresponding to a light-like kappa-deformation of Poincaré algebra. The adventage of the second one is that it is expressed solely in terms of Poincaré generators. In contrast to this, the Abelian twist goes out of the boundaries of Poincaré algebra and runs into envelope of the general linear algebra. Some of the physical applications of these two different twist operators are considered. In particular, we use the Abelian twist to construct the statistics flip operator compatible with the action of deformed symmetry group. Furthermore, we use the light-like twist operator to define a star product and subsequently to formulate a free scalar field theory compatible with kappa-Poincaré Hopf algebra and appropriate for considering the interacting ϕ 4 scalar field model on kappa-deformed space. (paper)

  2. Modeling and development of a twisting wing using inductively heated shape memory alloy actuators

    Science.gov (United States)

    Saunders, Robert N.; Hartl, Darren J.; Boyd, James G.; Lagoudas, Dimitris C.

    2015-04-01

    Wing twisting has been shown to improve aircraft flight performance. The potential benefits of a twisting wing are often outweighed by the mass of the system required to twist the wing. Shape memory alloy (SMA) actuators repeatedly demonstrate abilities and properties that are ideal for aerospace actuation systems. Recent advances have shown an SMA torsional actuator that can be manufactured and trained with the ability to generate large twisting deformations under substantial loading. The primary disadvantage of implementing large SMA actuators has been their slow actuation time compared to conventional actuators. However, inductive heating of an SMA actuator allows it to generate a full actuation cycle in just seconds rather than minutes while still . The aim of this work is to demonstrate an experimental wing being twisted to approximately 10 degrees by using an inductively heated SMA torsional actuator. This study also considers a 3-D electromagnetic thermo-mechanical model of the SMA-wing system and compare these results to experiments to demonstrate modeling capabilities.

  3. Borel resummation of soft gluon radiation and higher twists

    International Nuclear Information System (INIS)

    Forte, Stefano; Ridolfi, Giovanni; Rojo, Joan; Ubiali, Maria

    2006-01-01

    We show that the well-known divergence of the perturbative expansion of resummed results for processes such as deep-inelastic scattering and Drell-Yan in the soft limit can be treated by Borel resummation. The divergence in the Borel inversion can be removed by the inclusion of suitable higher twist terms. This provides us with an alternative to the standard 'minimal prescription' for the asymptotic summation of the perturbative expansion, and it gives us some handle on the role of higher twist corrections in the soft resummation region

  4. Note on twisted elliptic genus of K3 surface

    International Nuclear Information System (INIS)

    Eguchi, Tohru; Hikami, Kazuhiro

    2011-01-01

    We discuss the possibility of Mathieu group M 24 acting as symmetry group on the K3 elliptic genus as proposed recently by Ooguri, Tachikawa and one of the present authors. One way of testing this proposal is to derive the twisted elliptic genera for all conjugacy classes of M 24 so that we can determine the unique decomposition of expansion coefficients of K3 elliptic genus into irreducible representations of M 24 . In this Letter we obtain all the hitherto unknown twisted elliptic genera and find a strong evidence of Mathieu moonshine.

  5. Polarization-dependent diffraction in all-dielectric, twisted-band structures

    Energy Technology Data Exchange (ETDEWEB)

    Kardaś, Tomasz M.; Jagodnicka, Anna; Wasylczyk, Piotr, E-mail: pwasylcz@fuw.edu.pl [Photonic Nanostructure Facility, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Pasteura 5, 02-093 Warszawa (Poland)

    2015-11-23

    We propose a concept for light polarization management: polarization-dependent diffraction in all-dielectric microstructures. Numerical simulations of light propagation show that with an appropriately configured array of twisted bands, such structures may exhibit zero birefringence and at the same time diffract two circular polarizations with different efficiencies. Non-birefringent structures as thin as 3 μm have a significant difference in diffraction efficiency for left- and right-hand circular polarizations. We identify the structural parameters of such twisted-band matrices for optimum performance as circular polarizers.

  6. An in-line fiber-optic modal interferometer for simultaneous measurement of twist and ambient temperature

    Directory of Open Access Journals (Sweden)

    Yongqin Yu

    2014-12-01

    Full Text Available A novel and simple sensor based on fiber-optic modal interferometer fabricated by a segment of low elliptical hollow-core photonic bandgap fiber for simultaneous temperature and twist measurements is demonstrated. Meanwhile the sensor can also measure the twist angle and determine the twist direction simultaneously. The mode distribution of EHC-PBGF is demonstrated both in theory and experiments. There is an obvious difference of two transmission dips on the temperature and twist. The twist sensitivities of Dip 1 and Dip 2 are obtained to be −31.95 and −585.8 pm/(rad/m, respectively. The temperature sensitivities are 12.99 pm/°C for Dip 1 and 5.09 pm/°C for Dip 2, respectively. Two parameters of twist and temperature can be distinguished and measured simultaneously by using a sensing matrix. Meanwhile the structure is found to be weakly sensitive to the axial strain. It has the advantage of avoiding the crosstalk of strain in the applications.

  7. Twisted Vector Bundles on Pointed Nodal Curves

    Indian Academy of Sciences (India)

    Abstract. Motivated by the quest for a good compactification of the moduli space of -bundles on a nodal curve we establish a striking relationship between Abramovich's and Vistoli's twisted bundles and Gieseker vector bundles.

  8. Repairing and Upgrading Your PC

    CERN Document Server

    Thompson, Robert

    2009-01-01

    Repairing and Upgrading Your PC delivers start-to-finish instructions, simple enough for even the most inexperienced PC owner, for troubleshooting, repairing, and upgrading your computer. Written by hardware experts Robert Bruce Thompson and Barbara Fritchman Thompson, this book covers it all: how to troubleshoot a troublesome PC, how to identify which components make sense for an upgrade, and how to tear it all down and put it back together. This book shows how to repair and upgrade all of your PC's essential components.

  9. Topological twist in four dimensions, R-duality and hyperinstantons

    International Nuclear Information System (INIS)

    Anselmi, D.; Fre, P.

    1993-01-01

    In this paper we continue the programme of topologically twisting N=2 theories in D=4, focusing on the coupling of vector multiplets to N=2 supergravity. We show that in the minimal case, namely when the special gometry prepotential F(X) is a quadratic polynomial, the theory has a so far unknown on-shell U(1) symmetry, that we name R-duality. R-duality is a generalization of the chiral-dual on-shell symmetry of N=2 pure supergravity and of the R-symmetry of N=2 super Yang-Mills theory. Thanks to this, the theory can be topologically twisted and topologically shifted, precisely as pure N=2 supergravity, to yield a natural coupling of topological gravity to topological Yang-Mills theory. The gauge-fixing condition that emerges from the twisting is the self-duality condition on the gauge field strength and on the spin connection. Hence our theory reduces to intersection theory in the moduli-space of gauge instantons living in gravitational instanton backgrounds. We remark that, for deep properties of the parent N=2 theory, the topological Yang-Mills theory we obtain by taking the flat space limit of our gravity-coupled lagrangian is different from the Donaldson theory constructed by Witten. Whether this difference is substantial and what its geometrical implications may be is yet to be seen. We also discuss the topological twist of the hypermultiplets leading to topological quaternionic sigma-models. The instantons of these models, named by us hyperinstantons, correspond to a notion of triholomorphic mappings discussed in the paper. In all cases the new ghost number is the sum of the old ghost number plus the R-duality charge. The observables described by the theory are briefly discussed. In conclusion, the topological twist of the complete N=2 theory defines intersection theory in the moduli-space of gauge instantons plus gravitational instantons plus hyperinstantons. This is possibly a new subject for further mathematical investigation. (orig.)

  10. Controlling coupled bending-twisting vibrations of anisotropic composite wing

    Science.gov (United States)

    Ryabov, Victor; Yartsev, Boris

    2018-05-01

    The paper discusses the possibility to control coupled bending-twisting vibrations of anisotropic composite wing by means of the monoclinic structures in the reinforcement of the plating. Decomposing the potential straining energy and kinetic energy of natural vibration modes into interacting and non-interacting parts, it became possible to introduce the two coefficients that integrally consider the effect of geometry and reinforcement structure upon the dynamic response parameters of the wing. The first of these coefficients describes the elastic coupling of the natural vibration modes, the second coefficient describes the inertial one. The paper describes the numerical studies showing how the orientation of considerably anisotropic CRP layers in the plating affects natural frequencies, loss factors, coefficients of elastic and inertial coupling for several lower tones of natural bending-twisting vibrations of the wing. Besides, for each vibration mode, partial values of the above mentioned dynamic response parameters were determined by means of the relationships for orthotropic structures where instead of "free" shearing modulus in the reinforcement plant, "pure" shearing modulus is used. Joint analysis of the obtained results has shown that each pair of bending-twisting vibration modes has its orientation angle ranges of the reinforcing layers where the inertial coupling caused by asymmetry of the cross-section profile with respect to the main axes of inertia decreases, down to the complete extinction, due to the generation of the elastic coupling in the plating material. These ranges are characterized by the two main features: 1) the difference in the natural frequencies of the investigated pair of bending-twisting vibration modes is the minimum and 2) natural frequencies of bending-twisting vibrations belong to a stretch restricted by corresponding partial natural frequencies of the investigated pair of vibration modes. This result is of practical importance

  11. Hardy Inequalities in Globally Twisted Waveguides

    Czech Academy of Sciences Publication Activity Database

    Briet, Ph.; Hammedi, H.; Krejčiřík, David

    2015-01-01

    Roč. 105, č. 7 (2015), s. 939-958 ISSN 0377-9017 R&D Projects: GA ČR(CZ) GA14-06818S Institutional support: RVO:61389005 Keywords : quantum waveguides * twisted tubes * Dirichlet Laplacian * Hardy inequality Subject RIV: BE - Theoretical Physics Impact factor: 1.517, year: 2015

  12. One-dimensional structures behind twisted and untwisted superYang-Mills theory

    CERN Document Server

    Baulieu, Laurent

    2011-01-01

    We give a one-dimensional interpretation of the four-dimensional twisted N=1 superYang-Mills theory on a Kaehler manifold by performing an appropriate dimensional reduction. We prove the existence of a 6-generator superalgebra, which does not possess any invariant Lagrangian but contains two different subalgebras that determine the twisted and untwisted formulations of the N=1 superYang-Mills theory.

  13. The PC graphics handbook

    CERN Document Server

    Sanchez, Julio

    2003-01-01

    Part I - Graphics Fundamentals PC GRAPHICS OVERVIEW History and Evolution Short History of PC Video PS/2 Video Systems SuperVGA Graphics Coprocessors and Accelerators Graphics Applications State-of-the-Art in PC Graphics 3D Application Programming Interfaces POLYGONAL MODELING Vector and Raster Data Coordinate Systems Modeling with Polygons IMAGE TRANSFORMATIONS Matrix-based Representations Matrix Arithmetic 3D Transformations PROGRAMMING MATRIX TRANSFORMATIONS Numeric Data in Matrix Form Array Processing PROJECTIONS AND RENDERING Perspective The Rendering Pipeline LIGHTING AND SHADING Lightin

  14. Twisted mass, overlap and Creutz fermions. Cut-off effects at tree-level of perturbation theory

    International Nuclear Information System (INIS)

    Cichy, K.; Kujawa, A.; Jansen, K.; Shindler, A.

    2008-02-01

    We study cutoff effects at tree-level of perturbation theory for maximally twisted mass Wilson, overlap and the recently proposed Creutz fermions. We demonstrate that all three kind of lattice fermions exhibit the expected O(a 2 ) scaling behaviour in the lattice spacing. In addition, the sizes of these cutoff effects are comparable for the three kinds of lattice fermions considered here. Furthermore, we analyze situations when twisted mass fermions are not exactly at maximal twist and when overlap fermions are studied in comparison to twisted mass fermions when the quark masses are not matched. (orig.)

  15. Twist and snai1 expression in pharyngeal squamous cell carcinoma stroma is related to cancer progression

    International Nuclear Information System (INIS)

    Jouppila-Mättö, Anna; Närkiö-Mäkelä, Mervi; Soini, Ylermi; Pukkila, Matti; Sironen, Reijo; Tuhkanen, Hanna; Mannermaa, Arto; Kosma, Veli-Matti

    2011-01-01

    Epithelial-mesenchymal transition (EMT) is a crucial process in tumorigenesis since tumor cells attain fibroblast-like features enabling them to invade to surrounding tissue. Two transcription factors, TWIST and SNAI1, are fundamental in regulating EMT. Immunohistochemistry was used to study the expression of TWIST and SNAI1 in 109 pharyngeal squamous cell carcinomas. Tumors with intense stromal staining of TWIST relapsed more frequently (p = 0.04). Tumors with both positive TWIST and SNAI1 immunoreactivity in the stroma were at least Stage II (p = 0.05) and located more often in hypopharynx (p = 0.035). Tumors with negative immunostaining of TWIST and SNAI1 in the stromal compartment were smaller (T1-2) (p = 0.008), less advanced (SI-II) (p = 0.031) and located more often in the oropharynx (p = 0.007). Patients with negative SNAI1 and TWIST immunostaining in tumor stroma had a better 5-year disease-specific and overall survival (p = 0.037 and p = 0.014 respectively). TWIST and SNAI1 expression in stromal cells is associated with clinical and histopathological characteristics that indicate progressive disease. Negative expression of these EMT-promoting transcription factors predicts a better outcome

  16. PcToll2 positively regulates the expression of antimicrobial peptides by promoting PcATF4 translocation into the nucleus.

    Science.gov (United States)

    Lan, Jiang-Feng; Zhao, Li-Juan; Wei, Shun; Wang, Yuan; Lin, Li; Li, Xin-Cang

    2016-11-01

    Drosophila Toll and mammalian Toll-like receptors (TLRs) are a family of evolutionarily conserved immune receptors that play a crucial role in the first-line defense against intruded pathogens. Activating transcription factor 4 (ATF4), a member of the ATF/CREB transcription factor family, is an important factor that participates in TLR signaling and other physiological processes. However, in crustaceans, whether ATF4 homologs were involved in TLR signaling remains unclear. In the current study, we identified a Toll homolog PcToll2 and a novel ATF4 homolog PcATF4 from Procambarus clarkii, and analyzed the likely regulatory activity of PcATF4 in PcToll2 signaling. The complete cDNA sequence of PcToll2 was 4175 bp long containing an open reading frame of 2820 bp encoding a 939-amino acid protein, and the cDNA sequence of PcATF4 was 2027 bp long with an open reading frame of 1296 bp encoding a 431-amino acid protein. PcToll2 and human TLR4 shared the high identity and they were grouped into a cluster. Furthermore, PcToll2 had a close relationship with other shrimp TLRs that possessed potential antibacterial activity. PcToll2 was highly expressed in the hemocytes, heart and gills, while PcATF4 mainly distributed in gills. Upon challenge with Vibrio parahemolyticus, PcToll2 and PcATF4 together with the antimicrobial peptides of ALF1 and ALF2 were significantly up-regulated in the hemocytes, and the PcATF4 was translocated into the nucleus. After PcToll2 silencing and challenge with Vibrio, the translocation of PcATF4 into the nucleus was inhibited and the expression of ALF1 and ALF2 was reduced, but the expression of PcDorsal and PcSTAT was not affected. Furthermore, after PcATF4 knockdown and challenge with or without Vibrio, the expression of ALF1 and ALF2 was also decreased while the expression of PcToll2 was upregulated. These results suggested that PcToll2 might regulate the expression of ALF1 and ALF2 by promoting the import of PcATF4, instead of the routine

  17. Fiber-Optic Sensors for Measurements of Torsion, Twist and Rotation: A Review

    Directory of Open Access Journals (Sweden)

    Vedran Budinski

    2017-02-01

    Full Text Available Optical measurement of mechanical parameters is gaining significant commercial interest in different industry sectors. Torsion, twist and rotation are among the very frequently measured mechanical parameters. Recently, twist/torsion/rotation sensors have become a topic of intense fiber-optic sensor research. Various sensing concepts have been reported. Many of those have different properties and performances, and many of them still need to be proven in out-of-the laboratory use. This paper provides an overview of basic approaches and a review of current state-of-the-art in fiber optic sensors for measurements of torsion, twist and/or rotation.Invited Paper

  18. Design and analysis of variable-twist tiltrotor blades using shape memory alloy hybrid composites

    International Nuclear Information System (INIS)

    Park, Jae-Sang; Kim, Seong-Hwan; Jung, Sung Nam; Lee, Myeong-Kyu

    2011-01-01

    The tiltrotor blade, or proprotor, acts as a rotor in the helicopter mode and as a propeller in the airplane mode. For a better performance, the proprotor should have different built-in twist distributions along the blade span, suitable for each operational mode. This paper proposes a new variable-twist proprotor concept that can adjust the built-in twist distribution for given flight modes. For a variable-twist control, the present proprotor adopts shape memory alloy hybrid composites (SMAHC) containing shape memory alloy (SMA) wires embedded in the composite matrix. The proprotor of the Korea Aerospace Research Institute (KARI) Smart Unmanned Aerial Vehicle (SUAV), which is based on the tiltrotor concept, is used as a baseline proprotor model. The cross-sectional properties of the variable-twist proprotor are designed to maintain the cross-sectional properties of the original proprotor as closely as possible. However, the torsion stiffness is significantly reduced to accommodate the variable-twist control. A nonlinear flexible multibody dynamic analysis is employed to investigate the dynamic characteristics of the proprotor such as natural frequency and damping in the whirl flutter mode, the blade structural loads in a transition flight and the rotor performance in hover. The numerical results show that the present proprotor is designed to have a strong similarity to the baseline proprotor in dynamic and load characteristics. It is demonstrated that the present proprotor concept could be used to improve the hover performance adaptively when the variable-twist control using the SMAHC is applied appropriately

  19. Design and analysis of variable-twist tiltrotor blades using shape memory alloy hybrid composites

    Science.gov (United States)

    Park, Jae-Sang; Kim, Seong-Hwan; Jung, Sung Nam; Lee, Myeong-Kyu

    2011-01-01

    The tiltrotor blade, or proprotor, acts as a rotor in the helicopter mode and as a propeller in the airplane mode. For a better performance, the proprotor should have different built-in twist distributions along the blade span, suitable for each operational mode. This paper proposes a new variable-twist proprotor concept that can adjust the built-in twist distribution for given flight modes. For a variable-twist control, the present proprotor adopts shape memory alloy hybrid composites (SMAHC) containing shape memory alloy (SMA) wires embedded in the composite matrix. The proprotor of the Korea Aerospace Research Institute (KARI) Smart Unmanned Aerial Vehicle (SUAV), which is based on the tiltrotor concept, is used as a baseline proprotor model. The cross-sectional properties of the variable-twist proprotor are designed to maintain the cross-sectional properties of the original proprotor as closely as possible. However, the torsion stiffness is significantly reduced to accommodate the variable-twist control. A nonlinear flexible multibody dynamic analysis is employed to investigate the dynamic characteristics of the proprotor such as natural frequency and damping in the whirl flutter mode, the blade structural loads in a transition flight and the rotor performance in hover. The numerical results show that the present proprotor is designed to have a strong similarity to the baseline proprotor in dynamic and load characteristics. It is demonstrated that the present proprotor concept could be used to improve the hover performance adaptively when the variable-twist control using the SMAHC is applied appropriately.

  20. 'Twisted tape sign': Its significance in recurrent sigmoid volvulus

    International Nuclear Information System (INIS)

    Gopal, K.; Lim, Y.; Banerjee, B.

    2005-01-01

    Aim: Sigmoid volvulus is a common cause of intestinal obstruction in the elderly. Mild attacks of sigmoid volvulus may be more difficult to diagnose due to the lack of severity of symptoms which may resolve spontaneously only to recur after an interval. This study was a review of patients to assess the incidence of the 'twisted tape sign' and to evaluate the significance of its presence in cases of recurrent sigmoid volvulus. Methods and materials: A retrospective study over eight years revealed six cases of surgically confirmed recurrent sigmoid volvulus. Case records and barium enemas of all patients were reviewed. Results: Six patients were identified, including four men and two women, with a median age of 56 years. Diagnostic difficulties were encountered in four (67%) patients with a delay ranging between 10 and 37 months with a mean 17.3 months. Twisted tape sign was confirmed on all barium examinations retrospectively. Conclusion: Recognition of twisted tape sign on barium enema examination along with an appropriate clinical history would suggest a diagnosis of recurrent sigmoid volvulus

  1. Calculations of higher twist distribution functions in the MIT bag model

    International Nuclear Information System (INIS)

    Signal, A.I.

    1997-01-01

    We calculate all twist-2, -3 and -4 parton distribution functions involving two quark correlations using the wave function of the MIT bag model. The distributions are evolved up to experimental scales and combined to give the various nucleon structure functions. Comparisons with recent experimental data on higher twist structure functions at moderate values of Q 2 give good agreement with the calculated structure functions. (orig.)

  2. One-dimensional structures behind twisted and untwisted super Yang-Mills theory

    Energy Technology Data Exchange (ETDEWEB)

    Baulieu, Laurent [CERN, Geneve (Switzerland). Theoretical Div.; Toppan, Francesco, E-mail: baulieu@lpthe.jussieu.f, E-mail: toppan@cbpf.b [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil)

    2010-07-01

    We give a one-dimensional interpretation of the four-dimensional twisted N = 1 super Yang-Mills theory on a Kaehler manifold by performing an appropriate dimensional reduction. We prove the existence of a 6-generator superalgebra, which does not possess any invariant Lagrangian but contains two different subalgebras that determine the twisted and untwisted formulations of the N = 1 super Yang-Mills theory. (author)

  3. One-dimensional structures behind twisted and untwisted super Yang-Mills theory

    International Nuclear Information System (INIS)

    Baulieu, Laurent

    2010-01-01

    We give a one-dimensional interpretation of the four-dimensional twisted N = 1 super Yang-Mills theory on a Kaehler manifold by performing an appropriate dimensional reduction. We prove the existence of a 6-generator superalgebra, which does not possess any invariant Lagrangian but contains two different subalgebras that determine the twisted and untwisted formulations of the N = 1 super Yang-Mills theory. (author)

  4. Overlap valence quarks on an twisted mass sea

    Energy Technology Data Exchange (ETDEWEB)

    Cichy, K. [Adam Mickiewicz Univ., Poznan (Poland). Faculty of Physics; Drach, V.; Garcia-Ramos, E.; Herdoiza, G.; Jansen, K. [DESY, Zeuthen (Germany). John von Neumann-Institut fuer Computing NIC

    2010-12-15

    We present the results of an investigation of a mixed action approach of overlap valence and maximally twisted mass sea quarks. Employing a particular matching condition on the pion mass, we analyze the continuum limit scaling of the pion decay constant and the role of chiral zero modes of the overlap operator in this process. We employ gauge field configurations generated by the European Twisted Mass Collaboration with linear lattice size L ranging from 1.3 to 1.9 fm. The continuum limit is taken at a fixed value of L=1.3 fm, employing three values of the lattice spacing and two values of the pion mass constructed from sea quarks only. (orig.)

  5. Twisted tachyon condensation in closed string field theory

    International Nuclear Information System (INIS)

    Okawa, Yuji; Zwiebach, Barton

    2004-01-01

    We consider twisted tachyons on C/Z N orbifolds of bosonic closed string theory. It has been conjectured that these tachyonic instabilities correspond to decays of the orbifolds into flat space or into orbifolds with smaller deficit angles. We examine this conjecture using closed string field theory, with the string field truncated to low-level tachyons. We compute the tachyon potentials for C/Z 2 and C/Z 3 orbifolds and find critical points at depths that generate about 70% of the expected change in the deficit angle. We find that both twisted fields and untwisted modes localized near the apex of the cone acquire vacuum expectation values and contribute to the potential. (author)

  6. Twisted Bilayer Graphene. Interlayer configuration and magnetotransport signatures

    Energy Technology Data Exchange (ETDEWEB)

    Rode, Johannes C.; Smirnov, Dmitri; Belke, Christopher; Schmidt, Hennrik; Haug, Rolf J. [Institut fuer Festkoerperphysik, Hannover (Germany)

    2017-11-15

    Twisted Bilayer Graphene may be viewed as very first representative of the now booming class of artificially layered 2D materials. Consisting of two sheets from the same structure and atomic composition, its decisive degree of freedom lies in the rotation between crystallographic axes in the individual graphene monolayers. Geometrical consideration finds angle-dependent Moire patterns as well as commensurate superlattices of opposite sublattice exchange symmetry. Beyond the approach of rigidly interposed lattices, this review takes focus on the evolving topic of lattice corrugation and distortion in response to spatially varying lattice registry. The experimental approach to twisted bilayers requires a basic control over preparation techniques; important methods are summarized and extended on in the case of bilayers folded from monolayer graphene via AFM nanomachining. Central morphological parameters to the twisted bilayer, rotational mismatch and interlayer separation are studied in a broader base of samples. Finally, experimental evidence for a number of theoretically predicted, controversial electronic scenarios are reviewed; magnetotransport signatures are discussed in terms of Fermi velocity, van Hove singularities and Berry phase and assessed with respect to the underlying experimental conditions, thereby referring back to the initially considered variations in relaxed lattice structure. (copyright 2017 by WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  7. Higher-twist effects in the B → π transition form factor from QCD light-cone sum rules

    Energy Technology Data Exchange (ETDEWEB)

    Khodjamirian, Alexander; Rusov, Aleksey [Universitaet Siegen (Germany). Fakultaet IV, Department Physik, Theoretische Physik 1 Walter-Flex-Strasse 3 57068 Siegen

    2016-07-01

    I report on the progress in calculating new higher-twist corrections to the QCD light-cone sum rule for the B → π transition form factor. First, the expansion of the massive heavy-quark propagator in the external gluonic field near the light-cone was extended to include new terms containing the gluon-field strength derivatives. The resulting analytical expressions for the twist-5 and twist-6 contributions to the correlation function were obtained in a factorized approximation, expressed via the product of the quark-condensate density and the lower-twist pion distribution amplitudes. The numerical analysis of new higher-twist effects is in progress.

  8. Enhanced pump absorption efficiency in coiled and twisted double-clad thulium-doped fibers

    Czech Academy of Sciences Publication Activity Database

    Koška, Pavel; Peterka, Pavel; Aubrecht, Jan; Podrazký, Ondřej; Todorov, Filip; Becker, M.; Baravets, Yauhen; Honzátko, Pavel; Kašík, Ivan

    2016-01-01

    Roč. 24, č. 1 (2016), s. 102-107 ISSN 1094-4087 R&D Projects: GA TA ČR(CZ) TH01010997; GA MŠk(CZ) LD15122 Institutional support: RVO:67985882 Keywords : Thulium-doped fiber s * Fiber lasers * Double clad fiber s Subject RIV: BH - Optics , Masers, Lasers Impact factor: 3.307, year: 2016

  9. Note on twisted elliptic genus of K3 surface

    Energy Technology Data Exchange (ETDEWEB)

    Eguchi, Tohru, E-mail: eguchi@yukawa.kyoto-u.ac.j [Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto 606-8502 (Japan); Hikami, Kazuhiro, E-mail: KHikami@gmail.co [Department of Mathematics, Naruto University of Education, Tokushima 772-8502 (Japan)

    2011-01-03

    We discuss the possibility of Mathieu group M{sub 24} acting as symmetry group on the K3 elliptic genus as proposed recently by Ooguri, Tachikawa and one of the present authors. One way of testing this proposal is to derive the twisted elliptic genera for all conjugacy classes of M{sub 24} so that we can determine the unique decomposition of expansion coefficients of K3 elliptic genus into irreducible representations of M{sub 24}. In this Letter we obtain all the hitherto unknown twisted elliptic genera and find a strong evidence of Mathieu moonshine.

  10. Expansion of lower-frequency locally resonant band gaps using a double-sided stubbed composite phononic crystals plate with composite stubs

    Energy Technology Data Exchange (ETDEWEB)

    Li, Suobin; Chen, Tianning [School of Mechanical Engineering and State Key Laboratory for Strength and Vibration of Mechanical Structures, Xi' an Jiaotong University, Xi' an, Shaanxi 710049 (China); Wang, Xiaopeng, E-mail: xpwang@mail.xjtu.edu.cn [School of Mechanical Engineering and State Key Laboratory for Strength and Vibration of Mechanical Structures, Xi' an Jiaotong University, Xi' an, Shaanxi 710049 (China); Li, Yinggang [Key Laboratory of High Performance Ship Technology of Ministry of Education, Wuhan University of Technology, Wuhan, 430070 (China); Chen, Weihua [School of Mechanical Engineering and State Key Laboratory for Strength and Vibration of Mechanical Structures, Xi' an Jiaotong University, Xi' an, Shaanxi 710049 (China)

    2016-06-03

    We studied the expansion of locally resonant complete band gaps in two-dimensional phononic crystals (PCs) using a double-sided stubbed composite PC plate with composite stubs. Results show that the introduction of the proposed structure gives rise to a significant expansion of the relative bandwidth by a factor of 1.5 and decreases the opening location of the first complete band gap by a factor of 3 compared to the classic double-sided stubbed PC plate with composite stubs. Furthermore, more band gaps appear in the lower-frequency range (0.006). These phenomena can be attributed to the strong coupling between the “analogous rigid mode” of the stub and the anti-symmetric Lamb modes of the plate. The “analogous rigid mode” of the stub is produced by strengthening the localized resonance effect of the composite plates through the double-sided stubs, and is further strengthened through the introduction of composite stubs. The “analogous rigid mode” of the stubs expands the out-of-plane band gap, which overlaps with in-plane band gap in the lower-frequency range. As a result, the complete band gap is expanded and more complete band gaps appear. - Highlights: • Expansion of lower-frequency locally resonant BGs using novel composite phononic crystals plates. • The proposed structure expands the relative bandwidth 1.5 times compared to classic doubled-sided stubbed PC plates. • The opening location of the first complete BG decreases 3 times compared to the classic doubled-sided stubbed PC plates. • The concept “analogous rigid mode” is put forward to explain the expansion of lower-frequency BGs.

  11. CoPc and CoPcF16 on gold: Site-specific charge-transfer processes

    Directory of Open Access Journals (Sweden)

    Fotini Petraki

    2014-04-01

    Full Text Available Interface properties of cobalt(II phthalocyanine (CoPc and cobalt(II hexadecafluoro-phthalocyanine (CoPcF16 to gold are investigated by photo-excited electron spectroscopies (X-ray photoemission spectroscopy (XPS, ultraviolet photoemission spectroscopy (UPS and X-ray excited Auger electron spectroscopy (XAES. It is shown that a bidirectional charge transfer determines the interface energetics for CoPc and CoPcF16 on Au. Combined XPS and XAES measurements allow for the separation of chemical shifts based on different local charges at the considered atom caused by polarization effects. This facilitates a detailed discussion of energetic shifts of core level spectra. The data allow the discussion of site-specific charge-transfer processes.

  12. Families of vector-like deformations of relativistic quantum phase spaces, twists and symmetries

    Energy Technology Data Exchange (ETDEWEB)

    Meljanac, Daniel [Ruder Boskovic Institute, Division of Materials Physics, Zagreb (Croatia); Meljanac, Stjepan; Pikutic, Danijel [Ruder Boskovic Institute, Division of Theoretical Physics, Zagreb (Croatia)

    2017-12-15

    Families of vector-like deformed relativistic quantum phase spaces and corresponding realizations are analyzed. A method for a general construction of the star product is presented. The corresponding twist, expressed in terms of phase space coordinates, in the Hopf algebroid sense is presented. General linear realizations are considered and corresponding twists, in terms of momenta and Poincare-Weyl generators or gl(n) generators are constructed and R-matrix is discussed. A classification of linear realizations leading to vector-like deformed phase spaces is given. There are three types of spaces: (i) commutative spaces, (ii) κ-Minkowski spaces and (iii) κ-Snyder spaces. The corresponding star products are (i) associative and commutative (but non-local), (ii) associative and non-commutative and (iii) non-associative and non-commutative, respectively. Twisted symmetry algebras are considered. Transposed twists and left-right dual algebras are presented. Finally, some physical applications are discussed. (orig.)

  13. Families of vector-like deformations of relativistic quantum phase spaces, twists and symmetries

    International Nuclear Information System (INIS)

    Meljanac, Daniel; Meljanac, Stjepan; Pikutic, Danijel

    2017-01-01

    Families of vector-like deformed relativistic quantum phase spaces and corresponding realizations are analyzed. A method for a general construction of the star product is presented. The corresponding twist, expressed in terms of phase space coordinates, in the Hopf algebroid sense is presented. General linear realizations are considered and corresponding twists, in terms of momenta and Poincare-Weyl generators or gl(n) generators are constructed and R-matrix is discussed. A classification of linear realizations leading to vector-like deformed phase spaces is given. There are three types of spaces: (i) commutative spaces, (ii) κ-Minkowski spaces and (iii) κ-Snyder spaces. The corresponding star products are (i) associative and commutative (but non-local), (ii) associative and non-commutative and (iii) non-associative and non-commutative, respectively. Twisted symmetry algebras are considered. Transposed twists and left-right dual algebras are presented. Finally, some physical applications are discussed. (orig.)

  14. Families of vector-like deformations of relativistic quantum phase spaces, twists and symmetries

    Science.gov (United States)

    Meljanac, Daniel; Meljanac, Stjepan; Pikutić, Danijel

    2017-12-01

    Families of vector-like deformed relativistic quantum phase spaces and corresponding realizations are analyzed. A method for a general construction of the star product is presented. The corresponding twist, expressed in terms of phase space coordinates, in the Hopf algebroid sense is presented. General linear realizations are considered and corresponding twists, in terms of momenta and Poincaré-Weyl generators or gl(n) generators are constructed and R-matrix is discussed. A classification of linear realizations leading to vector-like deformed phase spaces is given. There are three types of spaces: (i) commutative spaces, (ii) κ -Minkowski spaces and (iii) κ -Snyder spaces. The corresponding star products are (i) associative and commutative (but non-local), (ii) associative and non-commutative and (iii) non-associative and non-commutative, respectively. Twisted symmetry algebras are considered. Transposed twists and left-right dual algebras are presented. Finally, some physical applications are discussed.

  15. Chiral tunneling in a twisted graphene bilayer.

    Science.gov (United States)

    He, Wen-Yu; Chu, Zhao-Dong; He, Lin

    2013-08-09

    The perfect transmission in a graphene monolayer and the perfect reflection in a Bernal graphene bilayer for electrons incident in the normal direction of a potential barrier are viewed as two incarnations of the Klein paradox. Here we show a new and unique incarnation of the Klein paradox. Owing to the different chiralities of the quasiparticles involved, the chiral fermions in a twisted graphene bilayer show an adjustable probability of chiral tunneling for normal incidence: they can be changed from perfect tunneling to partial or perfect reflection, or vice versa, by controlling either the height of the barrier or the incident energy. As well as addressing basic physics about how the chiral fermions with different chiralities tunnel through a barrier, our results provide a facile route to tune the electronic properties of the twisted graphene bilayer.

  16. Vacuum fluctuations of twisted fields in the space time of cosmic strings

    International Nuclear Information System (INIS)

    Matsas, G.E.A.

    1990-01-01

    A twisted scalar field conformally coupled to gravitation is used to calculate the vacuum stress-energy tensor in the background spacetime generated by an infinite straight gauge cosmic string. The result has an absolute numerical value close to the one obtained with a non-twisted conformal scalar field but their signals are opposite. (author) [pt

  17. The final measurements of the muon decay parameters from the TWIST experiment

    International Nuclear Information System (INIS)

    Bayes, R

    2013-01-01

    The TWIST (TRIUMF Weak Interaction Symmetry Test) experiment probes the Lorentz structure of the weak interaction using muon decay. This structure has a very well defined form under the Standard Model (SM) which makes precise predictions for the shape of the decay positron spectrum with respect to momentum and angle. The shape of the spectrum may be described under some rather general assumptions using a set of decay parameters whose values according to the SM are ρ = δ = 3/4, η = 0, and ξ = 1. TWIST uses a large sample of muon decays in a large acceptance spectrometer to measure the decay parameters to an order of magnitude greater precision than previous measurements. This experiment saw its last year of data collection in 2007. As TWIST is a systematics dominated experiment, much effort has been spent on refinements of the estimates of the systematic uncertainties over previous TWIST results. These proceedings will discuss the measures taken to achieve the precision goal of parts in 10 4 , and the physics implications of the experiment.

  18. Synthesis and structural determination of twisted MoS2 nanotubes

    International Nuclear Information System (INIS)

    Santiago, P.; Schabes-Retchkiman, P.; Ascencio, J.A.; Mendoza, D.; Perez-Alvarez, M.; Espinosa, A.; Reza-SanGerman, C.; Camacho-Bragado, G.A.; Jose-Yacaman, M.

    2004-01-01

    In the present work we report the synthesis of MoS 2 nanotubes with diameters greater than 10 nm using a template method. The length and properties of these nanotubes are a direct result of the preparation method. High-resolution transmission electron microscopy is used to study the structure of these highly curved entities. Molecular dynamics simulations of MoS 2 nanotubes reveal that one of the stable forms of the nanotubes is a twisted one. The twisting of the nanotubes produces a characteristic contrast in the images, which is also studied using simulation methods. The analysis of the local contrast close to the perpendicular orientation shows geometrical arrays of dots in domain-like structures, which are demonstrated to be a product of the atomic overlapping of irregular curvatures in the nanotubes. The configuration of some of the experimentally obtained nanotubes is demonstrated to be twisted with a behavior suggesting partial plasticity. (orig.)

  19. Output Feedback Control of Electro-Hydraulic Cylinder Drives using the Twisting Algorithm

    DEFF Research Database (Denmark)

    Schmidt, Lasse; Andersen, Torben Ole; Pedersen, Henrik C.

    2014-01-01

    contributions in literature. This paper considers the twisting algorithm when applied directly for output feedback control, and with the design based on a reduced order model representation of an arbitrary valve driven hydraulic cylinder drive. The consequence of implementing such a controller with the well......This paper discusses the utilization of the so-called twisting algorithm when applied in output feedback position control schemes for electro-hydraulic cylinder drives. The twisting controller was the first second order sliding controller ever introduced, and can structure-wise be considered...... feedback controller may be successfully applied to hydraulic valve driven cylinder drives, with performance being on the level with a conventional surface based first order sliding mode controller....

  20. Analysis of Twisting of Cellulose Nanofibrils in Atomistic Molecular Dynamics Simulations

    DEFF Research Database (Denmark)

    Paavilainen, S.; Rog, T.; Vattulainen, I.

    2011-01-01

    We use atomistic molecular dynamics simulations to study the crystal structure of cellulose nanofibrils, whose sizes are comparable with the crystalline parts in commercial nanocellulose. The simulations show twisting, whose rate of relaxation is strongly temperature dependent. Meanwhile......, no significant bending or stretching of nanocellulose is discovered. Considerations of atomic-scale interaction patterns bring about that the twisting arises from hydrogen bonding within and between the chains in a fibril....

  1. Tilting-Twisting-Rolling: a pen-based technique for compass geometric construction

    Institute of Scientific and Technical Information of China (English)

    Fei LYU; Feng TIAN; Guozhong DAI; Hongan WANG

    2017-01-01

    This paper presents a new pen-based technique,Tilting-Twisting-Rolling,to support compass geometric construction.By leveraging the 3D orientation information and 3D rotation information of a pen,this technique allows smooth pen action to complete multi-step geometric construction without switching task states.Results from a user study show this Tilting-Twisting-Rolling technique can improve user performance and user experience in compass geometric construction.

  2. Impact of higher twist terms on the analysis of scaling violation

    International Nuclear Information System (INIS)

    Barnett, R.M.

    1979-09-01

    A critical discussion is given of analyses of scaling violation in deep-inelastic scattering in the context of QCD. Several possible approaches are examined. Higher twist contributions are defined, and it is shown that they can have a crucial impact on tests of QCD. Higher twist terms can dramatically affect R = sigma/sub L//sigma/sub T/. QCD may be harder to test than previously realized. 17 references

  3. Fiber-Optic Sensors for Measurements of Torsion, Twist and Rotation: A Review †

    Science.gov (United States)

    Budinski, Vedran; Donlagic, Denis

    2017-01-01

    Optical measurement of mechanical parameters is gaining significant commercial interest in different industry sectors. Torsion, twist and rotation are among the very frequently measured mechanical parameters. Recently, twist/torsion/rotation sensors have become a topic of intense fiber-optic sensor research. Various sensing concepts have been reported. Many of those have different properties and performances, and many of them still need to be proven in out-of-the laboratory use. This paper provides an overview of basic approaches and a review of current state-of-the-art in fiber optic sensors for measurements of torsion, twist and/or rotation. PMID:28241510

  4. Bogoliubov coefficients for the twist operator in the D1D5 CFT

    Directory of Open Access Journals (Sweden)

    Zaq Carson

    2014-12-01

    Full Text Available The D1D5 CFT is a holographic dual of a near-extremal black hole in string theory. The interaction in this theory involves a twist operator which joins together different copies of a free CFT. Given a large number of D1 and D5 branes, the effective length of the circle on which the CFT lives is very large. We develop a technique to study the effect of the twist operator in the limit where the wavelengths of excitations are short compared to this effective length, which we call the ‘continuum limit’. The method uses Bogoliubov coefficients to compute the effect of the twist operator in this limit. For bosonic fields, we use the method to reproduce recent results describing the effect of the twist operator when it links together CFT copies with windings M and N, producing a copy of winding M+N. We also comment on possible generalizations of our results. The methods developed here may help in understanding the twist interaction at higher orders. This in turn should provide insight into the thermalization process in the D1D5 CFT, which gives a holographic description of black hole formation.

  5. Twisted mass lattice QCD

    International Nuclear Information System (INIS)

    Shindler, A.

    2007-07-01

    I review the theoretical foundations, properties as well as the simulation results obtained so far of a variant of the Wilson lattice QCD formulation: Wilson twisted mass lattice QCD. Emphasis is put on the discretization errors and on the effects of these discretization errors on the phase structure for Wilson-like fermions in the chiral limit. The possibility to use in lattice simulations different lattice actions for sea and valence quarks to ease the renormalization patterns of phenomenologically relevant local operators, is also discussed. (orig.)

  6. Twisted mass lattice QCD

    Energy Technology Data Exchange (ETDEWEB)

    Shindler, A. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC

    2007-07-15

    I review the theoretical foundations, properties as well as the simulation results obtained so far of a variant of the Wilson lattice QCD formulation: Wilson twisted mass lattice QCD. Emphasis is put on the discretization errors and on the effects of these discretization errors on the phase structure for Wilson-like fermions in the chiral limit. The possibility to use in lattice simulations different lattice actions for sea and valence quarks to ease the renormalization patterns of phenomenologically relevant local operators, is also discussed. (orig.)

  7. Modeling higher twist contributions to deep inelastic scattering with diquarks

    International Nuclear Information System (INIS)

    Anselmino, M.

    1994-01-01

    The most recent detailed data on the unpolarized nucleon structure functions allow a precise determination of higher twist contributions. Quark-quark correlations induced by color forces are expected to be a natural explanation for such effects; indeed, a quark-diquark picture of the nucleon, previously introduced in the description of several exclusive processes at intermediate Q 2 values, is found to model the proton higher twist data with great accuracy. The resulting parameters are consistent with the diquark properties suggested by other experimental and theoretical analyses. (author)

  8. PC/104 Embedded IOCs at Jefferson Lab

    International Nuclear Information System (INIS)

    Yan, Jianxun; Allison, Trent; Witherspoon, Sue; Cuffe, Anthony

    2009-01-01

    Jefferson Lab has developed embedded IOCs based on PC/104 single board computers (SBC) for low level control systems. The PC/104 IOCs run EPICS on top of the RTEMS operating system. Two types of control system configurations are used in different applications, PC/104 SBC with commercial PC/104 I/O cards and PC/104 SBC with custom designed FPGA-based boards. RTEMS was built with CEXP shell to run on the PC/104 SBC. CEXP shell provides the function of dynamic object loading, which is similar to the widely used VxWorks operating system. Standard software configurations were setup for PC/104 IOC application development to provide a familiar format for new projects as well as ease the conversion of applications from VME based IOCs to PC/104 IOCs. Many new projects at Jefferson Lab are going to employ PC/104 SBCs as IOCs and some applications have already been running them for accelerator operations. The PC/104 - RTEMS IOC provides a free open source Real-Time Operating System (RTOS), low cost/maintenance, easily installed/ configured, flexible, and reliable solution for accelerator control and 12GeV Upgrade projects.

  9. Functional Analysis of Mouse G6pc1 Mutations Using a Novel In Situ Assay for Glucose-6-Phosphatase Activity and the Effect of Mutations in Conserved Human G6PC1/G6PC2 Amino Acids on G6PC2 Protein Expression.

    Directory of Open Access Journals (Sweden)

    Kayla A Boortz

    Full Text Available Elevated fasting blood glucose (FBG has been associated with increased risk for development of type 2 diabetes. Single nucleotide polymorphisms (SNPs in G6PC2 are the most important common determinants of variations in FBG in humans. Studies using G6pc2 knockout mice suggest that G6pc2 regulates the glucose sensitivity of insulin secretion. G6PC2 and the related G6PC1 and G6PC3 genes encode glucose-6-phosphatase catalytic subunits. This study describes a functional analysis of 22 non-synonymous G6PC2 SNPs, that alter amino acids that are conserved in human G6PC1, mouse G6pc1 and mouse G6pc2, with the goal of identifying variants that potentially affect G6PC2 activity/expression. Published data suggest strong conservation of catalytically important amino acids between all four proteins and the related G6PC3 isoform. Because human G6PC2 has very low glucose-6-phosphatase activity we used an indirect approach, examining the effect of these SNPs on mouse G6pc1 activity. Using a novel in situ functional assay for glucose-6-phosphatase activity we demonstrate that the amino acid changes associated with the human G6PC2 rs144254880 (Arg79Gln, rs149663725 (Gly114Arg and rs2232326 (Ser324Pro SNPs reduce mouse G6pc1 enzyme activity without affecting protein expression. The Arg79Gln variant alters an amino acid mutation of which, in G6PC1, has previously been shown to cause glycogen storage disease type 1a. We also demonstrate that the rs368382511 (Gly8Glu, rs138726309 (His177Tyr, rs2232323 (Tyr207Ser rs374055555 (Arg293Trp, rs2232326 (Ser324Pro, rs137857125 (Pro313Leu and rs2232327 (Pro340Leu SNPs confer decreased G6PC2 protein expression. In summary, these studies identify multiple G6PC2 variants that have the potential to be associated with altered FBG in humans.

  10. An empirically-based model for the lift coefficients of twisted airfoils with leading-edge tubercles

    Science.gov (United States)

    Ni, Zao; Su, Tsung-chow; Dhanak, Manhar

    2018-04-01

    Experimental data for untwisted airfoils are utilized to propose a model for predicting the lift coefficients of twisted airfoils with leading-edge tubercles. The effectiveness of the empirical model is verified through comparison with results of a corresponding computational fluid-dynamic (CFD) study. The CFD study is carried out for both twisted and untwisted airfoils with tubercles, the latter shown to compare well with available experimental data. Lift coefficients of twisted airfoils predicted from the proposed empirically-based model match well with the corresponding coefficients determined using the verified CFD study. Flow details obtained from the latter provide better insight into the underlying mechanism and behavior at stall of twisted airfoils with leading edge tubercles.

  11. A torsional artificial muscle from twisted nitinol microwire

    Science.gov (United States)

    Mirvakili, Seyed M.; Hunter, Ian W.

    2017-04-01

    Nitinol microwires of 25 μm in diameter can have tensile actuation of up to 4.5% in less than 100 ms. A work density of up to 480 MPa can be achieved from these microwires. In the present work, we are showing that by twisting the microwires in form of closed-loop two-ply yarn we can create a torsional actuator. We achieved a revisable torsional stroke of 46°/mm with peak rotational speed of up to 10,000 rpm. We measured a gravimetric torque of up to 28.5 N•m/kg which is higher than the 3 - 6 N•m/kg for direct-drive commercial electric motors. These remarkable performance results are comparable to those of guest-infiltrated carbon nanotube twisted yarns.

  12. Effect of Lowering Twist Levels on Quality Parameters of Rotor Spun Cotton Yarn

    Directory of Open Access Journals (Sweden)

    FAROOQ AHMED

    2016-07-01

    Full Text Available Investigations were made to explore the influence of lowering twist level on quality characteristics of rotor spun yarn. Three levels of yarn linear density (i.e. 40, 35 and 30 tex and five levels of twist (i.e. 700, 600, 550, 500, and 450 were employed during yarn spinning trials. Each twist multiple was investigated at all linear densities for tensile strength, elongation, total CVm (Coefficient of Mass Variation imperfection index and hairiness. 100% cotton yarn samples were prepared on Reiter R-40 at rotor speed of 90,000 rpm. Determination of elongation, yarn strength, hairiness, mass variation, and total imperfections index was carried out on Uster Tensorapid-4 and Uster Tester-4 as per set standards of ISO standard test methods. Based on investigations it is established that yarn strength and elongation declined minutely (Insignificant with lowering twist levels but still can be confidently used for knitting yarns. However, significant improvement in total imperfection index and marginal enhancement in CVm were experienced.

  13. Closing Gaps in Geometrically Frustrated Symmetric Clusters: Local Equivalence between Discrete Curvature and Twist Transformations

    Directory of Open Access Journals (Sweden)

    Fang Fang

    2018-05-01

    Full Text Available In geometrically frustrated clusters of polyhedra, gaps between faces can be closed without distorting the polyhedra by the long established method of discrete curvature, which consists of curving the space into a fourth dimension, resulting in a dihedral angle at the joint between polyhedra in 4D. An alternative method—the twist method—has been recently suggested for a particular case, whereby the gaps are closed by twisting the cluster in 3D, resulting in an angular offset of the faces at the joint between adjacent polyhedral. In this paper, we show the general applicability of the twist method, for local clusters, and present the surprising result that both the required angle of the twist transformation and the consequent angle at the joint are the same, respectively, as the angle of bending to 4D in the discrete curvature and its resulting dihedral angle. The twist is therefore not only isomorphic, but isogonic (in terms of the rotation angles to discrete curvature. Our results apply to local clusters, but in the discussion we offer some justification for the conjecture that the isomorphism between twist and discrete curvature can be extended globally. Furthermore, we present examples for tetrahedral clusters with three-, four-, and fivefold symmetry.

  14. How the embryonic brain tube twists

    Science.gov (United States)

    Chen, Zi; Guo, Qiaohang; Forsch, Nickolas; Taber, Larry

    2014-03-01

    During early development, the tubular brain of the chick embryo undergoes a combination of progressive ventral bending and rightward torsion. This deformation is one of the major organ-level symmetry-breaking events in development. Available evidence suggests that bending is caused by differential growth, but the mechanism for torsion remains poorly understood. Since the heart almost always loops in the same direction that the brain twists, researchers have speculated that heart looping affects the direction of brain torsion. However, direct evidence is virtually nonexistent, nor is the mechanical origin of such torsion understood. In our study, experimental perturbations show that the bending and torsional deformations in the brain are coupled and that the vitelline membrane applies an external load necessary for torsion to occur. In addition, the asymmetry of the looping heart gives rise to the chirality of the twisted brain. A computational model is used to interpret these findings. Our work clarifies the mechanical origins of brain torsion and the associated left-right asymmetry, reminiscent of D'Arcy Thompson's view of biological form as ``diagram of forces''.

  15. Twisted boundary states and representation of generalized fusion algebra

    International Nuclear Information System (INIS)

    Ishikawa, Hiroshi; Tani, Taro

    2006-01-01

    The mutual consistency of boundary conditions twisted by an automorphism group G of the chiral algebra is studied for general modular invariants of rational conformal field theories. We show that a consistent set of twisted boundary states associated with any modular invariant realizes a non-negative integer matrix representation (NIM-rep) of the generalized fusion algebra, an extension of the fusion algebra by representations of the twisted chiral algebra associated with the automorphism group G. We check this result for several concrete cases. In particular, we find that two NIM-reps of the fusion algebra for su(3) k (k=3,5) are organized into a NIM-rep of the generalized fusion algebra for the charge-conjugation automorphism of su(3) k . We point out that the generalized fusion algebra is non-commutative if G is non-Abelian and provide some examples for G-bar S 3 . Finally, we give an argument that the graph fusion algebra associated with simple current extensions coincides with the generalized fusion algebra for the extended chiral algebra, and thereby explain that the graph fusion algebra contains the fusion algebra of the extended theory as a subalgebra

  16. Twisted Frobenius Identities from Vertex Operator Superalgebras

    Directory of Open Access Journals (Sweden)

    Alexander Zuevsky

    2017-01-01

    Full Text Available In consideration of the continuous orbifold partition function and a generating function for all n-point correlation functions for the rank two free fermion vertex operator superalgebra on the self-sewing torus, we introduce the twisted version of Frobenius identity.

  17. PC'eren på arbejde. 3. udgave

    DEFF Research Database (Denmark)

    Andersen, Povl Erik Rostgård

    En generel og ikke-programspecifik introduktion til edb-området med speciel fokus på pc'er og pc-programmel.......En generel og ikke-programspecifik introduktion til edb-området med speciel fokus på pc'er og pc-programmel....

  18. Analysis of a Caenorhabditis elegans Twist homolog identifies conserved and divergent aspects of mesodermal patterning

    OpenAIRE

    Harfe, Brian D.; Gomes, Ana Vaz; Kenyon, Cynthia; Liu, Jun; Krause, Michael; Fire, Andrew

    1998-01-01

    Mesodermal development is a multistep process in which cells become increasingly specialized to form specific tissue types. In Drosophila and mammals, proper segregation and patterning of the mesoderm involves the bHLH factor Twist. We investigated the activity of a Twist-related factor, CeTwist, during Caenorhabditis elegans mesoderm development. Embryonic mesoderm in C. elegans derives from a number of distinct founder cells that are specified during the early lineages; in contrast, a singl...

  19. Modelling higher twist contributions to deep inelastic scattering with diquarks

    International Nuclear Information System (INIS)

    Anselmino, M.; Caruso, F.; Penna Firme, A.; Soares, J.; Mello Neto, J.R.T. de

    1994-08-01

    The most recent detailed data on the unpolarized nucleon structure functions allow a precise determination of higher twist contributions. Quark-quark correlations induced by colour forces are expected to be a natural explanation for such effects: indeed, a quark-diquark picture of the nucleon, previously introduced in the description of several exclusive processes at intermediate Q 2 values, is found to model the proton higher twist data with great accuracy. The resulting parameters are consistent with the diquark properties suggested by other experimental and theoretical analyses. (author). 15 refs, 5 figs

  20. The SU(∞) twisted gradient flow running coupling

    Energy Technology Data Exchange (ETDEWEB)

    Pérez, Margarita García [Instituto de Física Teórica UAM-CSIC,Nicolás Cabrera 13-15, E-28049-Madrid (Spain); González-Arroyo, Antonio [Instituto de Física Teórica UAM-CSIC,Nicolás Cabrera 13-15, E-28049-Madrid (Spain); Departamento de Física Teórica, C-15, Universidad Autónoma de Madrid,E-28049-Madrid (Spain); Keegan, Liam [PH-TH, CERN,CH-1211 Geneva 23 (Switzerland); Okawa, Masanori [Graduate School of Science, Hiroshima University,Higashi-Hiroshima, Hiroshima 739-8526 (Japan)

    2015-01-09

    We measure the running of the SU(∞) ’t Hooft coupling by performing a step scaling analysis of the Twisted Eguchi-Kawai (TEK) model, the SU(N) gauge theory on a single site lattice with twisted boundary conditions. The computation relies on the conjecture that finite volume effects for SU(N) gauge theories defined on a 4-dimensional twisted torus are controlled by an effective size parameter l-tilde=l√N, with l the torus period. We set the scale for the running coupling in terms of l-tilde and use the gradient flow to define a renormalized ’t Hooft coupling λ(l-tilde). In the TEK model, this idea allows the determination of the running of the coupling through a step scaling procedure that uses the rank of the group as a size parameter. The continuum renormalized coupling constant is extracted in the zero lattice spacing limit, which in the TEK model corresponds to the large N limit taken at fixed value of λ(l-tilde). The coupling constant is thus expected to coincide with that of the ordinary pure gauge theory at N=∞. The idea is shown to work and permits us to follow the evolution of the coupling over a wide range of scales. At weak coupling we find a remarkable agreement with the perturbative two-loop formula for the running coupling.

  1. Radiative capture of cold neutrons by protons and deuteron photodisintegration with twisted beams

    Science.gov (United States)

    Afanasev, Andrei; Serbo, Valeriy G.; Solyanik, Maria

    2018-05-01

    We consider two basic nuclear reactions: capture of neutrons by protons, n + p → γ + d, and its time-reversed counterpart, photodisintegration of the deuteron, γ + d → n + p. In both of these cases we assume that the incoming beam of neutrons or photons is ‘twisted’ by having an azimuthal phase dependence, i.e., it carries an additional angular momentum along its direction of propagation. Taking a low-energy limit of these reactions, we derive relations between corresponding transition amplitudes and cross sections with plane-wave beams and twisted beams. Implications for experiments with twisted cold neutrons and twisted photon beams are discussed.

  2. A tale with a Twist: a developmental gene with potential relevance for metabolic dysfunction and inflammation in adipose tissue

    Directory of Open Access Journals (Sweden)

    Anca Dana Dobrian

    2012-08-01

    Full Text Available The Twist proteins (Twist-1 and -2 are highly conserved developmental proteins with key roles for the transcriptional regulation in mesenchymal cell lineages. They belong to the super-family of bHLH proteins and exhibit bi-functional roles as both activators and repressors of gene transcription. The Twist proteins are expressed at low levels in adult tissues but may become abundantly re-expressed in cells undergoing malignant transformation. This observation prompted extensive research on the roles of Twist proteins in cancer progression and metastasis. Very recent studies indicate a novel role for Twist-1 as a potential regulator of adipose tissue remodeling and inflammation. Several studies suggested that developmental genes are important determinants of obesity, fat distribution and remodeling capacity of different adipose depots. Twist-1 is abundantly and selectively expressed in the adult adipose tissue and its constitutive expression is significantly higher in subcutaneous vs. visceral fat in both mice and humans. Moreover, Twist1 expression is strongly correlated with BMI and insulin resistance in humans. However, the functional roles and transcriptional downstream targets of Twist1 in adipose tissue are largely unexplored. The purpose of this review is to highlight the major findings related to Twist1 expression in different fat depots and cellular components of adipose tissue and to discuss the potential mechanisms suggesting a role for Twist1 in adipose tissue metabolism, inflammation and remodeling.

  3. Generalized Weyl modules for twisted current algebras

    Science.gov (United States)

    Makedonskyi, I. A.; Feigin, E. B.

    2017-08-01

    We introduce the notion of generalized Weyl modules for twisted current algebras. We study their representation-theoretic and combinatorial properties and also their connection with nonsymmetric Macdonald polynomials. As an application, we compute the dimension of the classical Weyl modules in the remaining unknown case.

  4. Increasing the Analytical Sensitivity by Oligonucleotides Modified with Para- and Ortho-Twisted Intercalating Nucleic Acids - TINA

    DEFF Research Database (Denmark)

    Schneider, Uffe V; Géci, Imrich; Jøhnk, Nina

    2011-01-01

    -TINA molecules increased the melting point (Tm) of Watson-Crick based antiparallel DNA duplexes. The increase in Tm was greatest when the intercalators were placed at the 5' and 3' termini (preferable) or, if placed internally, for each half or whole helix turn. Terminally positioned TINA molecules improved......The sensitivity and specificity of clinical diagnostic assays using DNA hybridization techniques are limited by the dissociation of double-stranded DNA (dsDNA) antiparallel duplex helices. This situation can be improved by addition of DNA stabilizing molecules such as nucleic acid intercalators....... Here, we report the synthesis of a novel ortho-Twisted Intercalating Nucleic Acid (TINA) amidite utilizing the phosphoramidite approach, and examine the stabilizing effect of ortho- and para-TINA molecules in antiparallel DNA duplex formation. In a thermal stability assay, ortho- and para...

  5. On the description of exclusive processes beyond the leading twist approximation

    International Nuclear Information System (INIS)

    Anikin, I.V.; Ivanov, D.Yu.; Pire, B.; Szymanowski, L.; Wallon, S.

    2010-01-01

    We describe hard exclusive processes beyond the leading twist approximation in a framework based on the Taylor expansion of the amplitude around the dominant light-cone directions. This naturally introduces an appropriate set of non-perturbative correlators whose number is minimalized after taking into account QCD equations of motion and the invariance under rotation on the light-cone. We exemplify this method at the twist 3 level and show that the coordinate and momentum space descriptions are fully equivalent.

  6. On the description of exclusive processes beyond the leading twist approximation

    Energy Technology Data Exchange (ETDEWEB)

    Anikin, I.V. [Bogoliubov Laboratory of Theoretical Physics, JINR, 141980 Dubna (Russian Federation); Ivanov, D.Yu. [Institute of Mathematics, 630090 Novosibirsk (Russian Federation); Pire, B., E-mail: pire@cpht.polytechnique.f [CPhT, Ecole Polytechnique, CNRS, F-91128 Palaiseau (France); Szymanowski, L. [Soltan Institute for Nuclear Studies, Hoza 69, 00-681 Warsaw (Poland); Wallon, S. [LPT, Universite d' Orsay, CNRS, 91404 Orsay (France); UPMC Univ. Paris 6, Faculte de Physique, 4 place Jussieu, 75252 Paris Cedex 05 (France)

    2010-01-04

    We describe hard exclusive processes beyond the leading twist approximation in a framework based on the Taylor expansion of the amplitude around the dominant light-cone directions. This naturally introduces an appropriate set of non-perturbative correlators whose number is minimalized after taking into account QCD equations of motion and the invariance under rotation on the light-cone. We exemplify this method at the twist 3 level and show that the coordinate and momentum space descriptions are fully equivalent.

  7. IBM PC/IX operating system evaluation plan

    Science.gov (United States)

    Dominick, Wayne D. (Editor); Granier, Martin; Hall, Philip P.; Triantafyllopoulos, Spiros

    1984-01-01

    An evaluation plan for the IBM PC/IX Operating System designed for IBM PC/XT computers is discussed. The evaluation plan covers the areas of performance measurement and evaluation, software facilities available, man-machine interface considerations, networking, and the suitability of PC/IX as a development environment within the University of Southwestern Louisiana NASA PC Research and Development project. In order to compare and evaluate the PC/IX system, comparisons with other available UNIX-based systems are also included.

  8. Artificial blood-flow controlling effects of inhomogeneity of twisted magnetic fields

    International Nuclear Information System (INIS)

    Nakagawa, Hidenori; Ohuchi, Mikio

    2017-01-01

    We developed a blood-flow controlling system using magnetic therapy for some types of nervous diseases. In our research, we utilized overlapped extremely low frequency (ELF) fields for the most effective blood-flow for the system. Results showed the possibility that the inhomogeneous region obtained by overlapping the fields at 50 Hz, namely, a desirably twisted field revealed a significant difference in induced electromotive forces at the insertion points of electrodes. In addition, ELF exposures with a high inhomogeneity of the twisted field at 50 Hz out of phase were more effective in generating an induced electromotive difference by approximately 31%, as contrasted with the difference generated by the exposure in phase. We expect that the increase of the inhomogeneity of the twisted field around a blood vessel can produce the most effective electromotive difference in the blood, and also moderately affect the excitable cells relating to the autonomic nervous system for an outstanding blood-flow control in vivo. - Highlights: • The principal aim of this research is to contribute to the utilization of the twisted fields for the most effective blood-flow in vivo. • Two newly designed coil systems were used for producing a desirably twisted magnetic field under the measuring domain in the flow channel. • Further, we investigated the magnetohydrodynamic efficiencies of a prototype of a magnetic device, which was converted from use as a commercial alternating magnetic therapy apparatus. • The system was well-constructed with a successful application of a plural exposure coil; therefore, we were able to detect a maximum of induced electromotive force in a fluid of an artificial solution as a substitute for blood. • This new finding demonstrates that the process of blood massotherapy by magnetic stimuli is a therapy for many diseases.

  9. Artificial blood-flow controlling effects of inhomogeneity of twisted magnetic fields

    Energy Technology Data Exchange (ETDEWEB)

    Nakagawa, Hidenori, E-mail: hnakagawa-tdt@umin.ac.jp; Ohuchi, Mikio

    2017-06-01

    We developed a blood-flow controlling system using magnetic therapy for some types of nervous diseases. In our research, we utilized overlapped extremely low frequency (ELF) fields for the most effective blood-flow for the system. Results showed the possibility that the inhomogeneous region obtained by overlapping the fields at 50 Hz, namely, a desirably twisted field revealed a significant difference in induced electromotive forces at the insertion points of electrodes. In addition, ELF exposures with a high inhomogeneity of the twisted field at 50 Hz out of phase were more effective in generating an induced electromotive difference by approximately 31%, as contrasted with the difference generated by the exposure in phase. We expect that the increase of the inhomogeneity of the twisted field around a blood vessel can produce the most effective electromotive difference in the blood, and also moderately affect the excitable cells relating to the autonomic nervous system for an outstanding blood-flow control in vivo. - Highlights: • The principal aim of this research is to contribute to the utilization of the twisted fields for the most effective blood-flow in vivo. • Two newly designed coil systems were used for producing a desirably twisted magnetic field under the measuring domain in the flow channel. • Further, we investigated the magnetohydrodynamic efficiencies of a prototype of a magnetic device, which was converted from use as a commercial alternating magnetic therapy apparatus. • The system was well-constructed with a successful application of a plural exposure coil; therefore, we were able to detect a maximum of induced electromotive force in a fluid of an artificial solution as a substitute for blood. • This new finding demonstrates that the process of blood massotherapy by magnetic stimuli is a therapy for many diseases.

  10. Influence of pitch, twist, and taper on a blade`s performance loss due to roughness

    Energy Technology Data Exchange (ETDEWEB)

    Tangler, J.L. [National Renewable Energy Lab., Golden, CO (United States)

    1996-12-31

    The purpose of this study was to determine the influence of blade geometric parameters such as pitch, twist, and taper on a blade`s sensitivity to leading edge roughness. The approach began with an evaluation of available test data of performance degradation due to roughness effects for several rotors. In addition to airfoil geometry, this evaluation suggested that a rotor`s sensitivity to roughness was also influenced by the blade geometric parameters. Parametric studies were conducted using the PROP computer code with wind-tunnel airfoil characteristics for smooth and rough surface conditions to quantify the performance loss due to roughness for tapered and twisted blades relative to a constant-chord, non-twisted blade at several blade pitch angles. The results indicate that a constant-chord, non-twisted blade pitched toward stall will have the greatest losses due to roughness. The use of twist, taper, and positive blade pitch angles all help reduce the angle-of-attack distribution along the blade for a given wind speed and the associated performance degradation due to roughness. 8 refs., 6 figs.

  11. Influence of pitch, twist, and taper on a blade`s performance loss due to roughness

    Energy Technology Data Exchange (ETDEWEB)

    Tangler, J.L. [National Renewable Energy Laboratory, Golden, Colorado (United States)

    1997-08-01

    The purpose of this study was to determine the influence of blade geometric parameters such as pitch, twist, and taper on a blade`s sensitivity to leading edge roughness. The approach began with an evaluation of available test data of performance degradation due to roughness effects for several rotors. In addition to airfoil geometry, this evaluation suggested that a rotor`s sensitivity to roughness was also influenced by the blade geometric parameters. Parametric studies were conducted using the PROP computer code with wind-tunnel airfoil characteristics for smooth and rough surface conditions to quantify the performance loss due to roughness for tapered and twisted blades relative to a constant-chord, non-twisted blade at several blade pitch angles. The results indicate that a constant-chord, non-twisted blade pitched toward stall will have the greatest losses due to roughness. The use of twist, taper, and positive blade pitch angles all help reduce the angle-of-attack distribution along the blade for a given wind speed and the associated performance degradation due to roughness. (au)

  12. Prestressed concrete cable-stayed bridge; PC shachokyo `Tajiri sky bridge` no seko

    Energy Technology Data Exchange (ETDEWEB)

    Kaida, Y.; Tsujino, F. [Osaka Prefectural Government Office, Osaka (Japan); Yamamoto, T.; Hishiki, Y.; Saito, K.

    1995-01-30

    The outline on the execution of PC cable-stayed bridge `Tajiri Sky Bridge` which was built at the opposite coast of Kansai International Airport was reported. This bridge is a double-sided suspension PC cable-stayed bridge with a tower height of 93.6 m having a main beam which is 26.3 m wide, featuring H-type main tower with one side beam, a smooth main beam structure, the leg top part with a large section, etc. A large-capacity factory manufacturing type non-grout cable with a pull strength of 1,900 ton class was adopted for the diagonal bracing. The leg top part is in a massive concrete structure so that, for avoiding the crack of cement due to temperature, a low heat build-up furnace cement was adopted, the water reducing agent was used, pre-cooling and side-clamping PC steel material were adopted and moderate pre-stress was introduced. In the execution of the connection part of the main beam, for preventing the deflection fluctuation due to the change of the main beam/main tower/diagonal bracing due to temperature and vibration due to wind, the earth anchor was used to tentatively fix the extended part. During execution, the wind velocity was strong reaching 25 m/s, which did not produce any problems. 1 ref., 24 figs., 3 tabs.

  13. γγ → M{sup +}M{sup -}(M = π, K) processes with twist-3 corrections in QCD

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Cong [Southwest University, School of Physical Science and Technology, Chongqing (China); Chinese Academy of Sciences, State Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Beijing (China); Zhou, Ming-Zhen; Chen, Hong [Southwest University, School of Physical Science and Technology, Chongqing (China)

    2017-04-15

    We study the γγ → M{sup +}M{sup -}(M = π, K) processes with the contributions from the two-particle twist-2 and twist-3 distribution amplitudes of pion and kaon mesons on BHL prescription in the standard hard-scattering approach. The results show that the contributions from twist-3 parts are actually not power suppressed compared with the leading-twist contributions in the low energy region. The cross sections with twist-3 corrections agree well with the experimental data in the two-photon center-of-mass energy W > 2.8 GeV and we also predict the cross section ratio σ{sub 0}(K{sup +}K{sup -})/σ{sub 0}(π{sup +}π{sup -}), which is compatible with the experimental data from TPC and Belle. (orig.)

  14. An estimate of higher twist at small xB and low Q2 based upon a saturation model

    International Nuclear Information System (INIS)

    Bartels, J.; Peters, K.

    2000-03-01

    We investigate the influence of higher twist corrections to deep inelastic structure functions in the low-Q 2 and small-x HERA region. We review the general features of the lowest-order QCD diagrams which contribute to twist-4 at small-x, in particular the sign structure of longitudinal and transverse structure functions which offers the possibility of strong cancellations in F 2 . For a numerical analysis we perform a twist analysis of the saturation model which has been very successful both in describing the structure function and the DIS diffractive cross section at HERA. As the main conclusion, twist 4 corrections are not small in F L or F T but in F 2 = F L + F T they almost cancel. We point out that F L analysis needs a large twist-4 correction. We also indicate the region of validity of the twist expansion. (orig.)

  15. Numerical investigation of heat transfer and friction factor characteristics in a circular tube fitted with V-cut twisted tape inserts.

    Science.gov (United States)

    Salman, Sami D; Kadhum, Abdul Amir H; Takriff, Mohd S; Mohamad, Abu Bakar

    2013-01-01

    Numerical investigation of the heat transfer and friction factor characteristics of a circular fitted with V-cut twisted tape (VCT) insert with twist ratio (y = 2.93) and different cut depths (w = 0.5, 1, and 1.5 cm) were studied for laminar flow using CFD package (FLUENT-6.3.26). The data obtained from plain tube were verified with the literature correlation to ensure the validation of simulation results. Classical twisted tape (CTT) with different twist ratios (y = 2.93, 3.91, 4.89) were also studied for comparison. The results show that the enhancement of heat transfer rate induced by the classical and V-cut twisted tape inserts increases with the Reynolds number and decreases with twist ratio. The results also revealed that the V-cut twisted tape with twist ratio y = 2.93 and cut depth w = 0.5 cm offered higher heat transfer rate with significant increases in friction factor than other tapes. In addition the results of V-cut twist tape compared with experimental and simulated data of right-left helical tape inserts (RLT), it is found that the V-cut twist tape offered better thermal contact between the surface and the fluid which ultimately leads to a high heat transfer coefficient. Consequently, 107% of maximum heat transfer was obtained by using this configuration.

  16. Junior PC-Kørekort

    DEFF Research Database (Denmark)

    Hansbøl, Mikala; Mathiasen, Helle

    udviklingsprojekt med forsøg med DANSK IT's Junior PC-kørekort® som metode og redskab til at evaluere og dokumentere elevernes IT-kompetencer. Projektet blev gennemført i perioden fra 2002-2003 og afsluttet i foråret 2003. Rapporten er baseret på kvalitative case studier af elever og læreres arbejde med Junior PC......-kørekort® prøverne. DANSK IT's Junior PC-kørekort® kan betragtes som et forsøg på at etablere en bestemt fælleskulturel tilgang til elevernes IT-kompetencer i folkeskolen. Ud fra et situeret læringsperspektiv problematiserer rapporten anvendelsen af de standardiserede prøver som metode til at dokumentere og evaluere...... elevernes IT-kompetencer. Rapporten (2MB) fylder 80 sider ekskl. bilag. Bemærk, at forskningsrapporten handler om Dansk IT's Junior PC-kørekort - ikke at forveksle med det IT-bevis for folkeskolens elever, som Undevisningsministeriet har udviklet. Dette IT-bevis koncept skiftede navn i januar 2004, hvor...

  17. RESONANT ABSORPTION OF AXISYMMETRIC MODES IN TWISTED MAGNETIC FLUX TUBES

    Energy Technology Data Exchange (ETDEWEB)

    Giagkiozis, I.; Verth, G. [Solar Plasma Physics Research Centre, School of Mathematics and Statistics, University of Sheffield, Hounsfield Road, Hicks Building, Sheffield, S3 7RH (United Kingdom); Goossens, M.; Doorsselaere, T. Van [Centre for mathematical Plasma Astrophysics, Mathematics Department, KU Leuven, Celestijnenlaan 200B bus 2400, B-3001 Leuven (Belgium); Fedun, V. [Department of Automatic Control and Systems Engineering, University of Sheffield, Mappin Street, Amy Johnson Building, Sheffield, S1 3JD (United Kingdom)

    2016-06-01

    It has been shown recently that magnetic twist and axisymmetric MHD modes are ubiquitous in the solar atmosphere, and therefore the study of resonant absorption for these modes has become a pressing issue because it can have important consequences for heating magnetic flux tubes in the solar atmosphere and the observed damping. In this investigation, for the first time, we calculate the damping rate for axisymmetric MHD waves in weakly twisted magnetic flux tubes. Our aim is to investigate the impact of resonant damping of these modes for solar atmospheric conditions. This analytical study is based on an idealized configuration of a straight magnetic flux tube with a weak magnetic twist inside as well as outside the tube. By implementing the conservation laws derived by Sakurai et al. and the analytic solutions for weakly twisted flux tubes obtained recently by Giagkiozis et al. we derive a dispersion relation for resonantly damped axisymmetric modes in the spectrum of the Alfvén continuum. We also obtain an insightful analytical expression for the damping rate in the long wavelength limit. Furthermore, it is shown that both the longitudinal magnetic field and the density, which are allowed to vary continuously in the inhomogeneous layer, have a significant impact on the damping time. Given the conditions in the solar atmosphere, resonantly damped axisymmetric modes are highly likely to be ubiquitous and play an important role in energy dissipation. We also suggest that, given the character of these waves, it is likely that they have already been observed in the guise of Alfvén waves.

  18. Twist and YB-1 gene expression in cervical cancer and precancerous tissue and their correlation with cell invasion

    Directory of Open Access Journals (Sweden)

    Qin Tian

    2017-04-01

    Full Text Available Objective: To study the correlation of Twist and YB-1 gene expression in cervical cancer and precancerous tissue with cell invasion. Methods: Cervical cancer tissue, precancerous tissue and normal cervical tissue surgically removed in our hospital between May 2013 and April 2015 were collected; immunohistochemical staining kits were used to detect the positive protein expression rate of Twist and YB-1 gene; fluorescence quantitative PCR kits were used to detect Twist, YB-1 and invasion gene mRNA expression. Results: Twist and YB-1 mRNA expression and positive protein expression rate as well as USP22, Rab11, Rac1 and ANXA5 mRNA expression in cervical cancer tissue and precancerous tissue were significantly higher than those in normal cervical tissue, Twist and YB-1 mRNA expression and positive protein expression rate as well as USP22, Rab11, Rac1 and ANXA5 mRNA expression in cervical cancer tissue were significantly higher than those in precancerous tissue; USP22, Rab11, Rac1 and ANXA5 mRNA expression in cervical cancer tissue and precancerous tissue with positive Twist and YB-1 expression were significantly higher than those in cervical cancer tissue and precancerous tissue with negative Twist and YB-1 expression. Conclusion: Highly expressed Twist and YB-1 in cervical cancer and precancerous tissue can promote cell invasion.

  19. Phosphatidylcholine (PC) biosynthesis in pancreatic islets of Langerhans

    International Nuclear Information System (INIS)

    Hoffman, J.M.; Laychock, S.G.

    1986-01-01

    Islets of Langerhans isolated from rat pancreata were incubated with [ 14 C]choline to determine the biosynthesis of PC by the CDP choline to determine the biosynthesis of PC by the CDPcholine pathway. Recovery of [ 14 C]PC in islet membranes was time-related, and stimulated by glucose (17mM) during 60 min. The rate of PC synthesis was constant during 60 min with glucose stimulation. In contrast, the sulfonylurea tolbutamide (2 mM) reduced the recovery of [ 14 C]choline in PC, and 8-bromo-cyclic AMP (5 mM) did not significantly affect [ 14 C]PC recovery. Incubation of islets in Ca 2+ -free medium enhanced glucose-stimulated recovery of [ 14 C]choline-labeled PC due to the inhibition of phospholipase and phospholipid hydrolysis. Inhibition of CTP:phosphocholine cytidylyltransferase with 5-deoxy-5'-isobutylthioadenosine (SIBA) reduced [ 14 C]PC levels and insulin release in a concentration dependent manner. Treatment with SIBA also reduced Mg 2+ -dependent Ca 2+ -ATPase activity in islet microsomes. Quantitation of membrane PC showed that glucose stimulation did not alter islet P levels. Thus, islet PC biosynthesis is linked to glucose stimulation and contributes to the maintenance of PC levels in membranes undergoing exocytosis and phospholipid hydrolysis. Adequate PC levels support Ca 2+ pump activity and secretory mechanisms

  20. Electric currents induced by twisted light in Quantum Rings.

    Science.gov (United States)

    Quinteiro, G F; Berakdar, J

    2009-10-26

    We theoretically investigate the generation of electric currents in quantum rings resulting from the optical excitation with twisted light. Our model describes the kinetics of electrons in a two-band model of a semiconductor-based mesoscopic quantum ring coupled to light having orbital angular momentum (twisted light). We find the analytical solution, which exhibits a "circular" photon-drag effect and an induced magnetization, suggesting that this system is the circular analog of that of a bulk semiconductor excited by plane waves. For realistic values of the electric field and material parameters, the computed electric current can be as large as microA; from an applied perspective, this opens new possibilities to the optical control of the magnetization in semiconductors.

  1. MAML1 and TWIST1 co-overexpression promote invasion of head and neck squamous cell carcinoma.

    Science.gov (United States)

    Ardalan Khales, Sima; Ebrahimi, Ehsan; Jahanzad, Eisa; Ardalan Khales, Sahar; Forghanifard, Mohammad Mahdi

    2018-01-15

    Head and neck squamous cell carcinoma (HNSCC) is the seventh most common cancer worldwide with considerable morbidity and mortality. Invasion and metastasis of HNSCC is a complex process involving multiple molecules and signaling pathways. Twist Family BHLH Transcription Factor 1 (TWIST1) and Mastermind-like 1 (MAML1) are essential in induction of epithelial-mesenchymal transition through direct regulation of implicated molecules in cellular adhesion, migration and invasion. Our aim in this study was to assess the clinical significance of MAML1 and TWIST1 expression in HNSCC, and elucidate the probable correlation between these genes to exhibit their possible associations with progression and metastasis of the disease. The gene expression profile of MAML1 and TWIST1 was assessed in fresh tumoral compared to distant tumor-free tissues of 55 HNSCC patients using quantitative real-time Polymerase chain reaction (PCR). Significant overexpression of MAML1 and TWIST1 mRNA was observed in 49.1% and 38.2% (P ˂ 0.05) of tumor specimens, respectively. Overexpression of MAML1 was associated with vascular invasion (P = 0.048). Concomitant overexpression of MAML1 and TWIST1 was significantly correlated to each other (P = 0.004). Co-overexpression of the genes was significantly correlated to the various clinicopathological indices of poor prognosis including depth of tumor invasion (P < 0.01), lymphatic invasion and grade of tumor cell differentiation (P < 0.05). Significant correlation between MAML1 and TWIST1 in HNSCC was revealed. This study was the first report elucidating MAML1 clinical relevance in HNSCC. These new findings suggest an oncogenic role for concomitant expression of MAML1 and TWIST1 genes in HNSCC invasion and metastasis. © 2018 John Wiley & Sons Australia, Ltd.

  2. Examination of higher-order twist contributions in parity-violating deep-inelastic electron-deuteron scattering

    International Nuclear Information System (INIS)

    Mantry, Sonny; Ramsey-Musolf, Michael J.; Sacco, Gian Franco

    2010-01-01

    We show that parity-violating deep-inelastic scattering (PVDIS) of longitudinally polarized electrons from deuterium can in principle be a relatively clean probe of higher twist quark-quark correlations beyond the parton model. As first observed by Bjorken and Wolfenstein, the dominant contribution to the electron polarization asymmetry, proportional to the axial vector electron coupling, receives corrections at twist four from the matrix element of a single four-quark operator. We reformulate the Bjorken-Wolfenstein argument in a matter suitable for the interpretation of experiments planned at the Thomas Jefferson National Accelerator Facility (JLab). In particular, we observe that because the contribution of the relevant twist-four operator satisfies the Callan-Gross relation, the ratio of parity-violating longitudinal and transverse cross sections, R γZ , is identical to that for purely electromagnetic scattering, R γ , up to perturbative and power-suppressed contributions. This result simplifies the interpretation of the asymmetry in terms of other possible novel hadronic and electroweak contributions. We use the results of MIT Bag Model calculations to estimate contributions of the relevant twist-four operator to the leading term in the asymmetry as a function of Bjorken x and Q 2 . We compare these estimates with possible leading twist corrections from violation of charge symmetry in the parton distribution functions.

  3. Twisting formula of epsilon factors

    Indian Academy of Sciences (India)

    Sazzad Ali Biswas

    2017-08-07

    Aug 7, 2017 ... In this article, we give a generalized twisting formula for ϵ(χ1χ2,ψ), when both χ1 and χ2 are ramified via the following local Jacobi sums. Let UF be the group of units in OF (ring of integers of F). For characters χ1, χ2 of F. × and a positive integer n, we define the local Jacobi sum. Jt(χ1,χ2, n) = ∑ x∈UF. Un.

  4. Artificial blood-flow controlling effects of inhomogeneity of twisted magnetic fields

    Science.gov (United States)

    Nakagawa, Hidenori; Ohuchi, Mikio

    2017-06-01

    We developed a blood-flow controlling system using magnetic therapy for some types of nervous diseases. In our research, we utilized overlapped extremely low frequency (ELF) fields for the most effective blood-flow for the system. Results showed the possibility that the inhomogeneous region obtained by overlapping the fields at 50 Hz, namely, a desirably twisted field revealed a significant difference in induced electromotive forces at the insertion points of electrodes. In addition, ELF exposures with a high inhomogeneity of the twisted field at 50 Hz out of phase were more effective in generating an induced electromotive difference by approximately 31%, as contrasted with the difference generated by the exposure in phase. We expect that the increase of the inhomogeneity of the twisted field around a blood vessel can produce the most effective electromotive difference in the blood, and also moderately affect the excitable cells relating to the autonomic nervous system for an outstanding blood-flow control in vivo.

  5. Quark mass anomalous dimension from the twisted mass Dirac operator spectrum

    Energy Technology Data Exchange (ETDEWEB)

    Cichy, Krzysztof [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Poznan Univ. (Poland). Faculty of Physics

    2013-12-15

    We investigate whether it is possible to extract the quark mass anomalous dimension and its scale dependence from the spectrum of the twisted mass Dirac operator in Lattice QCD. The answer to this question appears to be positive, provided that one goes to large enough eigenvalues, sufficiently above the non-perturbative regime. The obtained results are compared to continuum perturbation theory. By analyzing possible sources of systematic effects, we find the domain of applicability of the approach, extending from an energy scale of around 1.5 to 4 GeV. The lower limit is dictated by physics (non-perturbative effects at low energies), while the upper bound is set by the ultraviolet cut-off of present-day lattice simulations. We use gauge field configuration ensembles generated by the European Twisted Mass Collaboration (ETMC) with 2 flavours of dynamical twisted mass quarks, at 4 lattice spacings in the range between around 0.04 and 0.08 fm.

  6. Quark mass anomalous dimension from the twisted mass Dirac operator spectrum

    International Nuclear Information System (INIS)

    Cichy, Krzysztof; Poznan Univ.

    2013-12-01

    We investigate whether it is possible to extract the quark mass anomalous dimension and its scale dependence from the spectrum of the twisted mass Dirac operator in Lattice QCD. The answer to this question appears to be positive, provided that one goes to large enough eigenvalues, sufficiently above the non-perturbative regime. The obtained results are compared to continuum perturbation theory. By analyzing possible sources of systematic effects, we find the domain of applicability of the approach, extending from an energy scale of around 1.5 to 4 GeV. The lower limit is dictated by physics (non-perturbative effects at low energies), while the upper bound is set by the ultraviolet cut-off of present-day lattice simulations. We use gauge field configuration ensembles generated by the European Twisted Mass Collaboration (ETMC) with 2 flavours of dynamical twisted mass quarks, at 4 lattice spacings in the range between around 0.04 and 0.08 fm.

  7. Comparative Studies on Thermal Performance of Conic Cut Twist Tape Inserts with SiO2 and TiO2 Nanofluids

    Directory of Open Access Journals (Sweden)

    Sami D. Salman

    2015-01-01

    Full Text Available This paper presents a comparison study on thermal performance conic cut twist tape inserts in laminar flow of nanofluids through a constant heat fluxed tube. Three tape configurations, namely, quadrant cut twisted tape (QCT, parabolic half cut twisted tape (PCT, and triangular cut twisted (VCT of twist ratio y = 2.93 and cut depth de = 0.5 cm were used with 1% and 2% volume concentration of SiO2/water and TiO2/water nanofluids. Typical twist tape with twist ratio of y = 2.93 was used for comparison. The results show that the heat transfer was enhanced by increasing of Reynolds number and nanoparticles concentration of nanofluid. The results have also revealed that the use of twist tape enhanced the heat transfer coefficient significantly and maximum heat transfer enhancement was achieved by the presence of triangular cut twist tape insert with 2% volume concentration of SiO2 nanofluid. Over the range investigated, the maximum thermal performance factor of 5.13 is found with the simultaneous use of the SiO2 nanofluid at 2% volume concentration VCT at Reynolds number of 220. Furthermore, new empirical correlations for Nusselt number, friction factor, and thermal performance factor are developed and reported.

  8. A zero torsional stiffness twist morphing blade as a wind turbine load alleviation device

    Science.gov (United States)

    Lachenal, X.; Daynes, S.; Weaver, P. M.

    2013-06-01

    This paper presents the design, analysis and realization of a zero stiffness twist morphing wind turbine blade. The morphing blade is designed to actively twist as a means of alleviating the gust loads which reduce the fatigue life of wind turbine blades. The morphing structure exploits an elastic strain energy balance within the blade to enable large twisting deformations with modest actuation requirements. While twist is introduced using the warping of the blade skin, internal pre-stressed members ensure that a constant strain energy balance is achieved throughout the deformation, resulting in a zero torsional stiffness structure. The torsional stability of the morphing blade is characterized by analysing the elastic strain energy in the device. Analytical models of the skin, the pre-stressed components and the complete blade are compared to their respective finite element models as well as experimental results. The load alleviation potential of the adaptive structure is quantified using a two-dimensional steady flow aerodynamic model which is experimentally validated with wind tunnel measurements.

  9. Unwinding motion of a twisted active region filament

    Energy Technology Data Exchange (ETDEWEB)

    Yan, X. L.; Xue, Z. K.; Kong, D. F. [Yunnan Observatories, Chinese Academy of Sciences, Kunming 650011 (China); Liu, J. H. [Department of Physics, Shijiazhuang University, Shijiazhuang 050035 (China); Xu, C. L. [Yunnan Normal University, Kunming 650092 (China)

    2014-12-10

    To better understand the structures of active region filaments and the eruption process, we study an active region filament eruption in active region NOAA 11082 in detail on 2010 June 22. Before the filament eruption, the opposite unidirectional material flows appeared in succession along the spine of the filament. The rising of the filament triggered two B-class flares at the upper part of the filament. As the bright material was injected into the filament from the sites of the flares, the filament exhibited a rapid uplift accompanying the counterclockwise rotation of the filament body. From the expansion of the filament, we can see that the filament consisted of twisted magnetic field lines. The total twist of the filament is at least 5π obtained by using a time slice method. According to the morphology change during the filament eruption, it is found that the active region filament was a twisted flux rope and its unwinding motion was like a solar tornado. We also find that there was a continuous magnetic helicity injection before and during the filament eruption. It is confirmed that magnetic helicity can be transferred from the photosphere to the filament. Using the extrapolated potential fields, the average decay index of the background magnetic fields over the filament is 0.91. Consequently, these findings imply that the mechanism of solar filament eruption could be due to the kink instability and magnetic helicity accumulation.

  10. Time-varying wing-twist improves aerodynamic efficiency of forward flight in butterflies.

    Science.gov (United States)

    Zheng, Lingxiao; Hedrick, Tyson L; Mittal, Rajat

    2013-01-01

    Insect wings can undergo significant chordwise (camber) as well as spanwise (twist) deformation during flapping flight but the effect of these deformations is not well understood. The shape and size of butterfly wings leads to particularly large wing deformations, making them an ideal test case for investigation of these effects. Here we use computational models derived from experiments on free-flying butterflies to understand the effect of time-varying twist and camber on the aerodynamic performance of these insects. High-speed videogrammetry is used to capture the wing kinematics, including deformation, of a Painted Lady butterfly (Vanessa cardui) in untethered, forward flight. These experimental results are then analyzed computationally using a high-fidelity, three-dimensional, unsteady Navier-Stokes flow solver. For comparison to this case, a set of non-deforming, flat-plate wing (FPW) models of wing motion are synthesized and subjected to the same analysis along with a wing model that matches the time-varying wing-twist observed for the butterfly, but has no deformation in camber. The simulations show that the observed butterfly wing (OBW) outperforms all the flat-plate wings in terms of usable force production as well as the ratio of lift to power by at least 29% and 46%, respectively. This increase in efficiency of lift production is at least three-fold greater than reported for other insects. Interestingly, we also find that the twist-only-wing (TOW) model recovers much of the performance of the OBW, demonstrating that wing-twist, and not camber is key to forward flight in these insects. The implications of this on the design of flapping wing micro-aerial vehicles are discussed.

  11. Time-varying wing-twist improves aerodynamic efficiency of forward flight in butterflies.

    Directory of Open Access Journals (Sweden)

    Lingxiao Zheng

    Full Text Available Insect wings can undergo significant chordwise (camber as well as spanwise (twist deformation during flapping flight but the effect of these deformations is not well understood. The shape and size of butterfly wings leads to particularly large wing deformations, making them an ideal test case for investigation of these effects. Here we use computational models derived from experiments on free-flying butterflies to understand the effect of time-varying twist and camber on the aerodynamic performance of these insects. High-speed videogrammetry is used to capture the wing kinematics, including deformation, of a Painted Lady butterfly (Vanessa cardui in untethered, forward flight. These experimental results are then analyzed computationally using a high-fidelity, three-dimensional, unsteady Navier-Stokes flow solver. For comparison to this case, a set of non-deforming, flat-plate wing (FPW models of wing motion are synthesized and subjected to the same analysis along with a wing model that matches the time-varying wing-twist observed for the butterfly, but has no deformation in camber. The simulations show that the observed butterfly wing (OBW outperforms all the flat-plate wings in terms of usable force production as well as the ratio of lift to power by at least 29% and 46%, respectively. This increase in efficiency of lift production is at least three-fold greater than reported for other insects. Interestingly, we also find that the twist-only-wing (TOW model recovers much of the performance of the OBW, demonstrating that wing-twist, and not camber is key to forward flight in these insects. The implications of this on the design of flapping wing micro-aerial vehicles are discussed.

  12. The Effect of a Twisted Magnetic Field on the Phase Mixing of the Kink Magnetohydrodynamic Waves in Coronal Loops

    Energy Technology Data Exchange (ETDEWEB)

    Ebrahimi, Zanyar; Karami, Kayoomars [Department of Physics, University of Kurdistan, Pasdaran Street, P.O. Box 66177-15175, Sanandaj (Iran, Islamic Republic of); Soler, Roberto, E-mail: z.ebrahimi@uok.ac.ir [Departament de Física, Universitat de les Illes Balears, E-07122, Palma de Mallorca (Spain)

    2017-08-10

    There is observational evidence for the existence of a twisted magnetic field in the solar corona. This inspires us to investigate the effect of a twisted magnetic field on the evolution of magnetohydrodynamic (MHD) kink waves in coronal loops. With this aim, we solve the incompressible linearized MHD equations in a magnetically twisted nonuniform coronal flux tube in the limit of long wavelengths. Our results show that a twisted magnetic field can enhance or diminish the rate of phase mixing of the Alfvén continuum modes and the decay rate of the global kink oscillation depending on the twist model and the sign of the longitudinal ( k{sub z} ) and azimuthal ( m ) wavenumbers. Also, our results confirm that in the presence of a twisted magnetic field, when the sign of one of the two wavenumbers m and k {sub z} is changed, the symmetry with respect to the propagation direction is broken. Even a small amount of twist can have an important impact on the process of energy cascading to small scales.

  13. Effects of Head Size on the Performance of Twist-Off Bolts

    OpenAIRE

    Schnupp, Keith Otto

    2003-01-01

    This study examines a specific application of button-head type twist-off bolts. Currently, the Research Council on Structural Connections Specification (2000) removes the requirement for ASTM F436 washers (ASTM 2000a) under the bolt head of twist-off bolts where the head diameter equals or exceeds that of an ASTM F436 washer when oversized and slotted holes are used. The need for washers is also removed for A490 strength bolts used on steels with specified yield strengths less than 40 ksi p...

  14. Sweep-twist adaptive rotor blade : final project report.

    Energy Technology Data Exchange (ETDEWEB)

    Ashwill, Thomas D.

    2010-02-01

    Knight & Carver was contracted by Sandia National Laboratories to develop a Sweep Twist Adaptive Rotor (STAR) blade that reduced operating loads, thereby allowing a larger, more productive rotor. The blade design used outer blade sweep to create twist coupling without angled fiber. Knight & Carver successfully designed, fabricated, tested and evaluated STAR prototype blades. Through laboratory and field tests, Knight & Carver showed the STAR blade met the engineering design criteria and economic goals for the program. A STAR prototype was successfully tested in Tehachapi during 2008 and a large data set was collected to support engineering and commercial development of the technology. This report documents the methodology used to develop the STAR blade design and reviews the approach used for laboratory and field testing. The effort demonstrated that STAR technology can provide significantly greater energy capture without higher operating loads on the turbine.

  15. IL-6 stabilizes Twist and enhances tumor cell motility in head and neck cancer cells through activation of casein kinase 2.

    Directory of Open Access Journals (Sweden)

    Ying-Wen Su

    Full Text Available BACKGROUND: Squamous cell carcinoma of the head and neck (SCCHN is the seventh most common cancer worldwide. Unfortunately, the survival of patients with SCCHN has not improved in the last 40 years, and thus new targets for therapy are needed. Recently, elevations in serum level of interleukin 6 (IL-6 and expression of Twist in tumor samples were found to be associated with poor clinical outcomes in multiple types of cancer, including SCCHN. Although Twist has been proposed as a master regulator of epithelial-mesenchymal transition and metastasis in cancers, the mechanisms by which Twist levels are regulated post-translationally are not completely understood. Tumor progression is characterized by the involvement of cytokines and growth factors and Twist induction has been connected with a number of these signaling pathways including IL-6. Since many of the effects of IL-6 are mediated through activation of protein phosphorylation cascades, this implies that Twist expression must be under a tight control at the post-translational level in order to respond in a timely manner to external stimuli. METHODOLOGY/PRINCIPAL FINDINGS: Our data show that IL-6 increases Twist expression via a transcription-independent mechanism in many SCCHN cell lines. Further investigation revealed that IL-6 stabilizes Twist in SCCHN cell lines through casein kinase 2 (CK2 phosphorylation of Twist residues S18 and S20, and that this phosphorylation inhibits degradation of Twist. Twist phosphorylation not only increases its stability but also enhances cell motility. Thus, post-translational modulation of Twist contributes to its tumor-promoting properties. CONCLUSIONS/SIGNIFICANCE: Our study shows Twist expression can be regulated at the post-translational level through phosphorylation by CK2, which increases Twist stability in response to IL-6 stimulation. Our findings not only provide novel mechanistic insights into post-translational regulation of Twist but also suggest

  16. Ellipticity and twisting of the isophotes of some bright galaxies in Virgo

    International Nuclear Information System (INIS)

    Barbon, R.; Benacchio, L.; Capaccioli, M.

    1980-01-01

    Ellipticity and twisting of the isophotes of four lenticular and seven elliptical galaxies in the Virgo cluster are presented as a sample of a more complete photometric investigation. This work has been motivated by the increasing importance of this kind of information for the understanding of the spatial structure of E galaxies. The calibrated plate material from the Loiano 1.52 meter and Tautenburg Schmidt telescopes has been digitized with a PDS microdensitometer and analysed by means of the Interactive Numerical Mapping Package (INMP). Ellipticity and orientation profiles are presented in a graphical form together with a preliminary discussion. A correlation has been found between ellipticity and twisting in barred lenticulars which might help in the understanding of some E galaxies such as NGC 4406 and NGC 4374. Twisting has been detected in all of the seven ellipticals of the sample

  17. Quality assessment of platelet concentrates prepared by platelet rich plasma-platelet concentrate, buffy coat poor-platelet concentrate (BC-PC and apheresis-PC methods

    Directory of Open Access Journals (Sweden)

    Singh Ravindra

    2009-01-01

    Full Text Available Background: Platelet rich plasma-platelet concentrate (PRP-PC, buffy coat poor-platelet concentrate (BC-PC, and apheresis-PC were prepared and their quality parameters were assessed. Study Design: In this study, the following platelet products were prepared: from random donor platelets (i platelet rich plasma - platelet concentrate (PRP-PC, and (ii buffy coat poor- platelet concentrate (BC-PC and (iii single donor platelets (apheresis-PC by different methods. Their quality was assessed using the following parameters: swirling, volume of the platelet concentrate, platelet count, WBC count and pH. Results: A total of 146 platelet concentrates (64 of PRP-PC, 62 of BC-PC and 20 of apheresis-PC were enrolled in this study. The mean volume of PRP-PC, BC-PC and apheresis-PC was 62.30±22.68 ml, 68.81±22.95 ml and 214.05±9.91 ml and ranged from 22-135 ml, 32-133 ml and 200-251 ml respectively. The mean platelet count of PRP-PC, BC-PC and apheresis-PC was 7.6±2.97 x 1010/unit, 7.3±2.98 x 1010/unit and 4.13±1.32 x 1011/unit and ranged from 3.2-16.2 x 1010/unit, 0.6-16.4 x 1010/unit and 1.22-8.9 x 1011/unit respectively. The mean WBC count in PRP-PC (n = 10, BC-PC (n = 10 and apheresis-PC (n = 6 units was 4.05±0.48 x 107/unit, 2.08±0.39 x 107/unit and 4.8±0.8 x 106/unit and ranged from 3.4 -4.77 x 107/unit, 1.6-2.7 x 107/unit and 3.2 - 5.2 x 106/unit respectively. A total of 26 units were analyzed for pH changes. Out of these units, 10 each were PRP-PC and BC-PC and 6 units were apheresis-PC. Their mean pH was 6.7±0.26 (mean±SD and ranged from 6.5 - 7.0 and no difference was observed among all three types of platelet concentrate. Conclusion: PRP-PC and BC-PC units were comparable in terms of swirling, platelet count per unit and pH. As expected, we found WBC contamination to be less in BC-PC than PRP-PC units. Variation in volume was more in BC-PC than PRP-PC units and this suggests that further standardization is required for preparation of BC-PC

  18. Space confinement and rotation stress induced self-organization of double-helix nanostructure: a nanotube twist with a moving catalyst head.

    Science.gov (United States)

    Zhao, Meng-Qiang; Zhang, Qiang; Tian, Gui-Li; Huang, Jia-Qi; Wei, Fei

    2012-05-22

    Inorganic materials with double-helix structure have attracted intensive attention due to not only their elegant morphology but also their amazing morphology-related potential applications. The investigation on the formation mechanism of the inorganic double-helix nanostructure is the first step for the fundamental studies of their materials or physical properties. Herein, we demonstrated the space confinement and rotation stress induced self-organization mechanism of the carbon nanotube (CNT)-array double helices under scanning electron microscopy by directly observing their formation process from individual layered double hydroxide flakes, which is a kind of hydrotalcite-like material composed of positively charged layers and charge-balancing interlayer anions. Space confinement is considered to be the most important extrinsic factor for the formation of CNT-array double helices. Synchronous growth of the CNT arrays oppositely from LDH flakes with space confinement on both sides at the same time is essential for the growth of CNT-array double helices. Coiling of the as-grown CNT arrays into double helices will proceed by self-organization, tending to the most stable morphology in order to release their internal rotation stress. Based on the demonstrated mechanism, effective routes were carried out to improve the selectivity for CNT-array double helices. The work provides a promising method for the fabrication of double-helix nanostructures with their two helices connected at the end by self-assembly.

  19. PHYSICAL PROPERTIES OF THE CURRENT CENSUS OF NORTHERN WHITE DWARFS WITHIN 40 pc OF THE SUN

    International Nuclear Information System (INIS)

    Limoges, M.-M.; Bergeron, P.; Lépine, S.

    2015-01-01

    We present a detailed description of the physical properties of our current census of white dwarfs within 40 pc of the Sun, based on an exhaustive spectroscopic survey of northern hemisphere candidates from the SUPERBLINK proper motion database. Our method for selecting white dwarf candidates is based on a combination of theoretical color–magnitude relations and reduced proper motion diagrams. We reported in an earlier publication the discovery of nearly 200 new white dwarfs, and we present here the discovery of an additional 133 new white dwarfs, among which we identify 96 DA, 3 DB, 24 DC, 3 DQ, and 7 DZ stars. We further identify 178 white dwarfs that lie within 40 pc of the Sun, representing a 40% increase of the current census, which now includes 492 objects. We estimate the completeness of our survey at between 66% and 78%, allowing for uncertainties in the distance estimates. We also perform a homogeneous model atmosphere analysis of this 40 pc sample and find a large fraction of massive white dwarfs, indicating that we are successfully recovering the more massive, and less luminous objects often missed in other surveys. We also show that the 40 pc sample is dominated by cool and old white dwarfs, which populate the faint end of the luminosity function, although trigonometric parallaxes will be needed to shape this part of the luminosity function more accurately. Finally, we identify 4 probable members of the 20 pc sample, 4 suspected double degenerate binaries, and we also report the discovery of two new ZZ Ceti pulsators

  20. High Efficiency Large-Angle Pancharatnam Phase Deflector Based on Dual Twist Design

    Science.gov (United States)

    2016-12-16

    construction and characterization of a ±40° beam steering device with 90% diffraction efficiency based on our dual-twist design at 633nm wavelength...N. & Escuti, M. J. Achromatic Wollaston prism beam splitter using polarization gratings. Opt. Lett. 41, 4461–4463 (2016). 13. Slussarenko, S., et...High-efficiency large-angle Pancharatnam phase deflector based on dual-twist design Kun Gao1, Colin McGinty1, Harold Payson2, Shaun Berry2, Joseph

  1. Twist map, the extended Frenkel-Kontorova model and the devil's staircase

    International Nuclear Information System (INIS)

    Aubry, S.

    1982-01-01

    Exact results obtained on the discrete Frenkel Kontorova (FK) model and its extensions during the past few years are reviewed. These models are associated with area preserving twist maps of the cylinder (or a part of it) onto itself. The theorems obtained for the FK model thus yields new theorems for the twist maps. The exact structure of the ground-states which are either commensurate or incommensurate and assert the existence of elementary discommensurations under certain necessary and sufficient conditions is described. Necessary conditions for the trajectories to represent metastable configurations, which can be chaotic, are given. The existence of a finite Peierl Nabarro barrier for elementary discommensurations is connected with a property of non-integrability of the twist map. The existence of KAM tori corresponds to undefectible incommensurate ground-states and a theorem is given which asserts that when the phenon spectrum of an incommensurate ground-state exhibits a finite gap, then the corresponding trajectory is dense on a Cantor set with zero measure length. These theorems, when applied to the initial FK model, allows one to prove the existence of the transition by breaking of analyticity for the incommensurate structures when the parameter which describes the discrepancy of the model to the integrable limit varies. Finally, we describe a theorem proving the existence of a devil's staircase for the variation curve of the atomic mean distance versus a chemical potential, for certain properties of the twist map which are generally satisfied

  2. Favorable clinical outcome and unique characteristics in association with Twist1 overexpression in de novo acute myeloid leukemia

    International Nuclear Information System (INIS)

    Chen, C-C; You, J-Y; Gau, J-P; Huang, C-E; Chen, Y-Y; Tsai, Y-H; Chou, H-J; Lung, J; Yang, M-H

    2015-01-01

    Epithelial–mesenchymal transition (EMT) is a critical process for inducing stem-like properties of epithelial cancer cells. However, the role of EMT inducers in hematological malignancies is unknown. Twist1, an EMT inducer necessary for cell migration, has recently been found to have transcriptionally regulatory activity on the expression of Bmi1, and these two are capable of promoting tumorigenesis in a synergized manner. Knowing that Bmi1 expression is essential for maintenance of leukemic stem cells, we speculate that Twist1 might govern the pathogenesis of acute myeloid leukemia (AML) development as well. We found that upregulated Twist1 increased Bmi1 expression in AML and endued leukemic cells a higher proliferative potential and increased resistance to apoptosis. In primary AML samples, there was strong positive correlation between the expression levels of Twist1 and Bmi1. AML patients whose leukemic blasts harbored overexpressed Twist1 had a more aggressive clinical phenotype, but they were more likely to have a better clinical outcome after standard therapy. In vitro studies confirmed that Twist1-overexpressing leukemic cells were more susceptible to cytarabine, but not daunorubicin, cytotoxicity. Our findings suggest that, in a subset of AML patients, Twist1 has a prominent role in the pathogenesis of the disease that leads to unique clinical phenotypes

  3. First results of ETMC simulations with Nf=2+1+1 maximally twisted mass fermions

    NARCIS (Netherlands)

    Baron, R.; Blossier, B.; Boucaud, P.; Deuzeman, A.; Drach, V.; Farchioni, F.; Gimenez, V.; Herdoiza, G.; Jansen, K.; Michael, C.; Montvay, I.; Palao, D.; Pallante, E.; Pène, O.; Reker, S.; Urbach, C.; Wagner, M.; Wenger, U.; Collaboration, for the ETM

    2009-01-01

    We present first results from runs performed with Nf=2+1+1 flavours of dynamical twisted mass fermions at maximal twist: a degenerate light doublet and a mass split heavy doublet. An overview of the input parameters and tuning status of our ensembles is given, together with a comparison with results

  4. Knockdown of TWIST1 enhances arsenic trioxide- and ionizing radiation-induced cell death in lung cancer cells by promoting mitochondrial dysfunction

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Sung-Keum; Kim, Jae-Hee; Choi, Ha-Na [Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, 215-4 Gongneung-dong, Nowon-gu, Seoul (Korea, Republic of); Choe, Tae-Boo [Department of Microbiological Engineering, Kon-Kuk University, Gwangjin-gu, Seoul (Korea, Republic of); Hong, Seok-Il [Department of Laboratory Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, 215-4 Gongneung-dong, Nowon-gu, Seoul (Korea, Republic of); Yi, Jae-Youn [Laboratory of Modulation of Radiobiological Responses, Korea Institute of Radiological and Medical Sciences, 215-4 Gongneung-dong, Nowon-gu, Seoul (Korea, Republic of); Hwang, Sang-Gu [Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, 215-4 Gongneung-dong, Nowon-gu, Seoul (Korea, Republic of); Lee, Hyun-Gyu [Department of Microbiology and Immunology, College of Medicine, Yonsei University, 250 Seongsan-no, Seodaemun-gu, Seoul (Korea, Republic of); Lee, Yun-Han, E-mail: yhlee87@yuhs.ac [Department of Radiation Oncology, College of Medicine, Yonsei University, 250 Seongsan-no, Seodaemun-gu, Seoul (Korea, Republic of); Park, In-Chul, E-mail: parkic@kcch.re.kr [Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, 215-4 Gongneung-dong, Nowon-gu, Seoul (Korea, Republic of)

    2014-07-11

    Highlights: • Knockdown of TWIST1 enhanced ATO- and IR-induced cell death in NSCLCs. • Intracellular ROS levels were increased in cells treated with TWIST1 siRNA. • TWIST1 siRNA induced MMP loss and mitochondrial fragmentation. • TWIST1 siRNA upregulated the fission-related proteins FIS1 and DRP1. - Abstract: TWIST1 is implicated in the process of epithelial mesenchymal transition, metastasis, stemness, and drug resistance in cancer cells, and therefore is a potential target for cancer therapy. In the present study, we found that knockdown of TWIST1 by small interfering RNA (siRNA) enhanced arsenic trioxide (ATO)- and ionizing radiation (IR)-induced cell death in non-small-cell lung cancer cells. Interestingly, intracellular reactive oxygen species levels were increased in cells treated with TWIST1 siRNA and further increased by co-treatment with ATO or IR. Pretreatment of lung cancer cells with the antioxidant N-acetyl-cysteine markedly suppressed the cell death induced by combined treatment with TWIST1 siRNA and ATO or IR. Moreover, treatment of cells with TWIST1 siRNA induced mitochondrial membrane depolarization and significantly increased mitochondrial fragmentation (fission) and upregulated the fission-related proteins FIS1 and DRP1. Collectively, our results demonstrate that siRNA-mediated TWIST1 knockdown induces mitochondrial dysfunction and enhances IR- and ATO-induced cell death in lung cancer cells.

  5. BK-parameter from Nf=2 twisted mass lattice QCD

    International Nuclear Information System (INIS)

    Constantinou, M.; Dimopoulos, P.; Frezzotti, R.; INFN, Rome

    2011-01-01

    We present an unquenched N f = 2 lattice computation of the B K parameter which controls K 0 - anti K 0 oscillations. A partially quenched setup is employed with two maximally twisted dynamical (sea) light Wilson quarks, and valence quarks of both the maximally twisted and the Osterwalder-Seiler variety. Suitable combinations of these two kinds of valence quarks lead to a lattice definition of the B K parameter which is both multiplicatively renormalizable and O(a) improved. Employing the non-perturbative RI-MOM scheme, in the continuum limit and at the physical value of the pion mass we get B RGI K =0.729±0.030, a number well in line with the existing quenched and unquenched determinations. (orig.)

  6. Twist-writhe partitioning in a coarse-grained DNA minicircle model

    Science.gov (United States)

    Sayar, Mehmet; Avşaroǧlu, Barış; Kabakçıoǧlu, Alkan

    2010-04-01

    Here we present a systematic study of supercoil formation in DNA minicircles under varying linking number by using molecular-dynamics simulations of a two-bead coarse-grained model. Our model is designed with the purpose of simulating long chains without sacrificing the characteristic structural properties of the DNA molecule, such as its helicity, backbone directionality, and the presence of major and minor grooves. The model parameters are extracted directly from full-atomistic simulations of DNA oligomers via Boltzmann inversion; therefore, our results can be interpreted as an extrapolation of those simulations to presently inaccessible chain lengths and simulation times. Using this model, we measure the twist/writhe partitioning in DNA minicircles, in particular its dependence on the chain length and excess linking number. We observe an asymmetric supercoiling transition consistent with experiments. Our results suggest that the fraction of the linking number absorbed as twist and writhe is nontrivially dependent on chain length and excess linking number. Beyond the supercoiling transition, chains of the order of one persistence length carry equal amounts of twist and writhe. For longer chains, an increasing fraction of the linking number is absorbed by the writhe.

  7. Microwave modulation characteristics of twisted liquid crystals with chiral dopant

    Directory of Open Access Journals (Sweden)

    Rui Yuan

    2017-01-01

    Full Text Available Adding a chiral dopant in twisted nematic (TN liquid crystal cell can stabilize the orientation of liquid crystal molecules, particularly in high TN (HTN or super TN (STN liquid crystal cells. The difference in pitches in liquid crystal is induced by the chiral dopant, and these different pitches affect the orientation of liquid crystal director under an external applied voltage and influence the characteristics of microwave modulation. To illustrate this point, the microwave phase shift per unit length (MPSL versus voltage is calculated on the basis of the elastic theory of liquid crystal and the finite-difference iterative method. Enhancing the pitch induced by the chiral dopant in liquid crystal increases the MPSLs, but the stability of the twisted structures is decreased. Thus, appropriate pitches of 100d, 4d, and 2d can be applied in TN, HTN, and STN cells with cell gap d to enhance the characteristics of microwave modulation and stabilize the structures in twisted cell. This method can improve the characteristics of liquid crystal microwave modulators such that the operating voltage and the size of such phase shifters can be decreased.

  8. Twist-2 Light-Cone Pion Wave Function

    OpenAIRE

    Belyaev, V. M.; Johnson, Mikkel B.

    1997-01-01

    We present an analysis of the existing constraints for the twist-2 light-cone pion wave function. We find that existing information on the pion wave function does not exclude the possibility that the pion wave function attains its asymptotic form. New bounds on the parameters of the pion wave function are presented.

  9. Minimizing coupling loss by selection of twist pitch lengths in multi-stage cable-in-conduit conductors

    International Nuclear Information System (INIS)

    Rolando, G; Nijhuis, A; Devred, A

    2014-01-01

    The numerical code JackPot-ACDC (van Lanen et al 2010 Cryogenics 50 139–48, van Lanen et al 2011 IEEE Trans. Appl. Supercond. 21 1926–9, van Lanen et al 2012 Supercond. Sci. Technol. 25 025012) allows fast parametric studies of the electro-magnetic performance of cable-in-conduit conductors (CICCs). In this paper the code is applied to the analysis of the relation between twist pitch length sequence and coupling loss in multi-stage ITER-type CICCs. The code shows that in the analysed conductors the coupling loss is at its minimum when the twist pitches of the successive cabling stages have a length ratio close to one. It is also predicted that by careful selection of the stage-to-stage twist pitch ratio, CICCs cabled according to long twist schemes in the initial stages can achieve lower coupling loss than conductors with shorter pitches. The result is validated by AC loss measurements performed on prototype conductors for the ITER Central Solenoid featuring different twist pitch sequences. (paper)

  10. Photovoltaic performance and stability of fullerene/cerium oxide double electron transport layer superior to single one in p-i-n perovskite solar cells

    Science.gov (United States)

    Xing, Zhou; Li, Shu-Hui; Wu, Bao-Shan; Wang, Xin; Wang, Lu-Yao; Wang, Tan; Liu, Hao-Ran; Zhang, Mei-Lin; Yun, Da-Qin; Deng, Lin-Long; Xie, Su-Yuan; Huang, Rong-Bin; Zheng, Lan-Sun

    2018-06-01

    Interface engineering that involves in the metal cathodes and the electron transport layers (ETLs) facilitates the simultaneous improvement of device performances and stability in perovskite solar cells (PSCs). Herein, low-temperature solution-processed cerium oxide (CeOx) films are prepared by a facile sol-gel method and employed as the interface layers between [6,6]-phenyl-C61-butyric acid methyl ester (PC61BM) and an Ag back contact to form PC61BM/CeOx double ETLs. The introduction of CeOx enables electron extraction to the Ag electrode and protects the underlying perovskite layer and thus improves the device performance and stability of the p-i-n PSCs. The p-i-n PSCs with double PC61BM/CeOx ETLs demonstrate a maximum power conversion efficiency (PCE) of 17.35%, which is superior to those of the devices with either PC61BM or CeOx single ETLs. Moreover, PC61BM/CeOx devices exhibit excellent stability in light soaking, which is mainly due to the chemically stable CeOx interlayer. The results indicate that CeOx is a promising interface modification layer for stable high-efficiency PSCs.

  11. Investigation of the load on the lumbar region in nursing technique's movements - relation between twist and surface electromyogram.

    Science.gov (United States)

    Maekawa, Yasuko; Shiozaki, Akira; Majima, Yukie

    2009-01-01

    This study measured the twist angle of the lumbar region and the surface electromyogram (EMG) and examined their mutual relation to elucidate the degree and influence of factors of "twist" in nursing techniques as a cause of lower back pain. Using a goniometer (two-way angle and twist sensors) and an EMG(SX230; DKH Co., Ltd.), we conducted measurements by affixing the goniometer on the lumbar vertebral column and EMG sensor at four points of right and left sides of L2 and L4 (of the erector muscle of the spine). The measured nursing techniques were three common methods of "transferring a patient from bed to wheelchair," which is said to impart a heavy load on the lumbar region. Results show that the correlation value between the twist angle rate and mean energy is likely to be greater, suggesting that the magnitude of the load on the lumbar region should be related to the twist speed rather than to the twist angle of the movement itself.

  12. On the propagation and the twist of Gaussian light in first-order optical systems

    NARCIS (Netherlands)

    Bastiaans, M.J.; Nijhawan, O.P.; Gupta, A.K.; Musla, A.K.; Singh, Kehar

    1998-01-01

    A measure for the twist of Gaussian light is expressed in terms of the second-order moments of the Wigner distribution function. The propagation law for these moments through first-order optical systems is used to express the twist in the output plane in terms of moments in the input plane, and vice

  13. First results with two light flavours of quarks with maximally twisted mass

    International Nuclear Information System (INIS)

    Jansen, K.; Urbach, C.

    2006-10-01

    We report on first results of an ongoing effort to simulate lattice QCD with two degenerate flavours of quarks by means of the twisted mass formulation tuned to maximal twist. By utilising recent improvements of the HMC algorithm, pseudo-scalar masses well below 300 MeV are simulated on volumes L 3 .T with T=2L and L>2 fm and at values of the lattice spacing a f =2+1+1 flavours are discussed. (orig.)

  14. Scaling and χPT description of pions from Nf=2 twisted mass QCD

    International Nuclear Information System (INIS)

    Dimopoulos, Petros; Frezzotti, Roberto; Herdoiza, Gregorio; Jansen, Karl; Michael, Chris; Urbach, Carsten; Bonn Univ.

    2009-12-01

    We study light-quark observables by means of dynamical lattice QCD simulations using two flavours of twisted mass fermions at maximal twist. We employ chiral perturbation theory to describe our data for the pion mass and decay constant. In this way, we extract precise determinations for the low-energy constants of the effective theory as well as for the light-quark mass and the chiral condensate. (orig.)

  15. PC clusters at CERN's PC farm

    CERN Multimedia

    Patrice Loïez

    2001-01-01

    These Linux-based PC clusters are mainly used for batch and interactive data processing. When the LHC starts operation in 2008, it will produce enough data every year to fill a stack of CDS 20 km tall, so high quality processing is required. To further facilitate this the LHC Computing Grid (LCG) has been set up to share processing power between facilities around the world.

  16. Twisting and Writhing with George Ellery Hale

    Science.gov (United States)

    Canfield, Richard C.

    2013-06-01

    Early in his productive career in astronomy, George Ellery Hale developed innovative solar instrumentation that allowed him to make narrow-band images. Among the solar phenomena he discovered were sunspot vortices, which he attributed to storms akin to cyclones in our own atmosphere. Using the concept of magnetic helicity, physicists and mathematicians describe the topology of magnetic fields, including twisting and writhing. Our contemporary understanding of Hale's vortices as a consequence of large-scale twist in sunspot magnetic fields hinges on a key property of helicity: conservation. I will describe the critical role that this property plays, when applied to twist and writhe, in a fundamental aspect of global solar magnetism: the hemispheric and solar cycle dependences of active region electric currents with respect to magnetic fields. With the advent of unbroken sequences of high-resolution magnetic images, such as those presently available from the Helioseismic and Magnetic Imager on Solar Dynamics Observatory, the flux of magnetic helicity through the photosphere can be observed quantitatively. As magnetic flux tubes buoy up through the convection zone, buffeted and shredded by turbulence, they break up into fragments by repeated random bifurcation. We track these rising flux fragments in the photosphere, and calculate the flux of energy and magnetic helicity there. Using a quantitative model of coronal currents, we also track connections between these fragments to calculate the energy and magnetic helicity stored at topological interfaces that are in some ways analogous to the storage of stress at faults in the Earth's crust. Comparison of these values to solar flares and interplanetary coronal mass ejections implies that this is the primary storage mechanism for energy and magnetic helicity released in those phenomena, and suggests a useful tool for quantitative prediction of geomagnetic storms.

  17. Scaling effects in resonant coupling phenomena between fundamental and cladding modes in twisted microstructured optical fibers.

    Science.gov (United States)

    Napiorkowski, Maciej; Urbanczyk, Waclaw

    2018-04-30

    We show that in twisted microstructured optical fibers (MOFs) the coupling between the core and cladding modes can be obtained for helix pitch much greater than previously considered. We provide an analytical model describing scaling properties of the twisted MOFs, which relates coupling conditions to dimensionless ratios between the wavelength, the lattice pitch and the helix pitch of the twisted fiber. Furthermore, we verify our model using a rigorous numerical method based on the transformation optics formalism and study its limitations. The obtained results show that for appropriately designed twisted MOFs, distinct, high loss resonance peaks can be obtained in a broad wavelength range already for the fiber with 9 mm helix pitch, thus allowing for fabrication of coupling based devices using a less demanding method involving preform spinning.

  18. Strong CP, flavor, and twisted split fermions

    International Nuclear Information System (INIS)

    Harnik, Roni; Perez, Gilad; Schwartz, Matthew D.; Shirman, Yuri

    2005-01-01

    We present a natural solution to the strong CP problem in the context of split fermions. By assuming CP is spontaneously broken in the bulk, a weak CKM phase is created in the standard model due to a twisting in flavor space of the bulk fermion wavefunctions. But the strong CP phase remains zero, being essentially protected by parity in the bulk and CP on the branes. As always in models of spontaneous CP breaking, radiative corrections to theta bar from the standard model are tiny, but even higher dimension operators are not that dangerous. The twisting phenomenon was recently shown to be generic, and not to interfere with the way that split fermions naturally weaves small numbers into the standard model. It follows that out approach to strong CP is compatible with flavor, and we sketch a comprehensive model. We also look at deconstructed version of this setup which provides a viable 4D model of spontaneous CP breaking which is not in the Nelson-Barr class. (author)

  19. Õnnetu saatusega Oliver Twist Polanski meelevallas / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2005-01-01

    Mängufilm Charles Dickensi romaani järgi "Oliver Twist" : stsenarist Ronald Harwood : režissöör Roman Polanski : nimiosas Barney Clark, Fagin - Ben Kingsley : Suurbritannia - Tšehhi - Prantsusmaa - Itaalia 2005

  20. A zero torsional stiffness twist morphing blade as a wind turbine load alleviation device

    International Nuclear Information System (INIS)

    Lachenal, X; Daynes, S; Weaver, P M

    2013-01-01

    This paper presents the design, analysis and realization of a zero stiffness twist morphing wind turbine blade. The morphing blade is designed to actively twist as a means of alleviating the gust loads which reduce the fatigue life of wind turbine blades. The morphing structure exploits an elastic strain energy balance within the blade to enable large twisting deformations with modest actuation requirements. While twist is introduced using the warping of the blade skin, internal pre-stressed members ensure that a constant strain energy balance is achieved throughout the deformation, resulting in a zero torsional stiffness structure. The torsional stability of the morphing blade is characterized by analysing the elastic strain energy in the device. Analytical models of the skin, the pre-stressed components and the complete blade are compared to their respective finite element models as well as experimental results. The load alleviation potential of the adaptive structure is quantified using a two-dimensional steady flow aerodynamic model which is experimentally validated with wind tunnel measurements. (paper)

  1. On the exchange of orbital angular momentum between twisted photons and atomic electrons

    International Nuclear Information System (INIS)

    Davis, Basil S; Kaplan, L; McGuire, J H

    2013-01-01

    We obtain an expression for the matrix element for scattering of a twisted (Laguerre–Gaussian profile) photon from a hydrogen atom. We consider photons incoming with an orbital angular momentum (OAM) of ℓħ, carried by a factor of e iℓϕ not present in a plane-wave or pure Gaussian profile beam. The nature of the transfer of +2ℓ units of OAM from the photon to the azimuthal atomic quantum number of the atom is investigated. We obtain simple formulas for these OAM flip transitions for elastic forward scattering of twisted photons when the photon wavelength λ is large compared with the atomic target size a, and small compared with the Rayleigh range z R , which characterizes the collimation length of the twisted photon beam. (paper)

  2. Rule-based expert system to establish the linkage between yarn twist factor and end-use.

    CSIR Research Space (South Africa)

    Dlodlo, N

    2009-09-01

    Full Text Available of the fibre alignment to axis. The tex twist factor αtex is defined as: where: αtex is the tex twist factor, t = twist expressed in turns/metre (or turns/centimetre), Ti = the effective linear density (count) of the composite yarn expressed in tex... of staple fibre yarns. They can be classed by fibre length (e.g. short and long staple), by spinning system (e.g. ring and rotor), or by yarn construction (e.g. single, plied, cabled, multiple and fancy). Ring-spun yarns are produced on 1000/itex Tt=α m...

  3. Duality in twisted N=4 supersymmetric gauge theories in four dimensions

    CERN Document Server

    Labastida, J.M.F.; Lozano, Carlos

    1999-01-01

    We consider a twisted version of the four-dimensional N=4 supersymmetric Yang-Mills theory with gauge groups SU(2) and SO(3), and bare masses for two of its chiral multiplets, thereby breaking N=4 down to N=2. Using the wall-crossing technique introduced by Moore and Witten within the u-plane approach to twisted topological field theories, we compute the partition function and all the topological correlation functions for the case of simply-connected spin four-manifolds of simple type. By including 't Hooft fluxes, we analyse the properties of the resulting formulae under duality transformations. The partition function transforms in the same way as the one first presented by Vafa and Witten for another twist of the N=4 supersymmetric theory in their strong coupling test of S-duality. Both partition functions coincide on K3. The topological correlation functions turn out to transform covariantly under duality, following a simple pattern which seems to be inherent in a general type of topological quantum field ...

  4. 'Twisted tape sign': Its significance in recurrent sigmoid volvulus

    Energy Technology Data Exchange (ETDEWEB)

    Gopal, K. [Tameside and Glossop Acute Services NHS Trust, Fountain Street, Ashton-under-Lyne OL6 9RW (United Kingdom)]. E-mail: karthikgopal73@yahoo.co.uk; Lim, Y. [Tameside and Glossop Acute Services NHS Trust, Fountain Street, Ashton-under-Lyne OL6 9RW (United Kingdom); Banerjee, B. [Tameside and Glossop Acute Services NHS Trust, Fountain Street, Ashton-under-Lyne OL6 9RW (United Kingdom)

    2005-11-01

    Aim: Sigmoid volvulus is a common cause of intestinal obstruction in the elderly. Mild attacks of sigmoid volvulus may be more difficult to diagnose due to the lack of severity of symptoms which may resolve spontaneously only to recur after an interval. This study was a review of patients to assess the incidence of the 'twisted tape sign' and to evaluate the significance of its presence in cases of recurrent sigmoid volvulus. Methods and materials: A retrospective study over eight years revealed six cases of surgically confirmed recurrent sigmoid volvulus. Case records and barium enemas of all patients were reviewed. Results: Six patients were identified, including four men and two women, with a median age of 56 years. Diagnostic difficulties were encountered in four (67%) patients with a delay ranging between 10 and 37 months with a mean 17.3 months. Twisted tape sign was confirmed on all barium examinations retrospectively. Conclusion: Recognition of twisted tape sign on barium enema examination along with an appropriate clinical history would suggest a diagnosis of recurrent sigmoid volvulus.

  5. The Effects of Exercise Intensity vs. Metabolic State on the Variability and Magnitude of Left Ventricular Twist Mechanics during Exercise.

    Directory of Open Access Journals (Sweden)

    Craig Armstrong

    Full Text Available Increased left ventricular (LV twist and untwisting rate (LV twist mechanics are essential responses of the heart to exercise. However, previously a large variability in LV twist mechanics during exercise has been observed, which complicates the interpretation of results. This study aimed to determine some of the physiological sources of variability in LV twist mechanics during exercise. Sixteen healthy males (age: 22 ± 4 years, [Formula: see text]O2peak: 45.5 ± 6.9 ml∙kg-1∙min-1, range of individual anaerobic threshold (IAT: 32-69% of [Formula: see text]O2peak were assessed at rest and during exercise at: i the same relative exercise intensity, 40%peak, ii at 2% above IAT, and, iii at 40%peak with hypoxia (40%peak+HYP. LV volumes were not significantly different between exercise conditions (P > 0.05. However, the mean margin of error of LV twist was significantly lower (F2,47 = 2.08, P 0.05. Overall, LV twist mechanics were linearly related to rate pressure product. During exercise, the intra-individual variability of LV twist mechanics is smaller at the same relative exercise intensity compared with IAT. However, the absolute magnitude (degrees of LV twist mechanics appears to be associated with the prevailing rate pressure product. Exercise tests that evaluate LV twist mechanics should be standardised by relative exercise intensity and rate pressure product be taken into account when interpreting results.

  6. The Effects of Exercise Intensity vs. Metabolic State on the Variability and Magnitude of Left Ventricular Twist Mechanics during Exercise

    Science.gov (United States)

    Armstrong, Craig; Samuel, Jake; Yarlett, Andrew; Cooper, Stephen-Mark; Stembridge, Mike; Stöhr, Eric J.

    2016-01-01

    Increased left ventricular (LV) twist and untwisting rate (LV twist mechanics) are essential responses of the heart to exercise. However, previously a large variability in LV twist mechanics during exercise has been observed, which complicates the interpretation of results. This study aimed to determine some of the physiological sources of variability in LV twist mechanics during exercise. Sixteen healthy males (age: 22 ± 4 years, V˙O2peak: 45.5 ± 6.9 ml∙kg-1∙min-1, range of individual anaerobic threshold (IAT): 32–69% of V˙O2peak) were assessed at rest and during exercise at: i) the same relative exercise intensity, 40%peak, ii) at 2% above IAT, and, iii) at 40%peak with hypoxia (40%peak+HYP). LV volumes were not significantly different between exercise conditions (P > 0.05). However, the mean margin of error of LV twist was significantly lower (F2,47 = 2.08, P 0.05). Overall, LV twist mechanics were linearly related to rate pressure product. During exercise, the intra-individual variability of LV twist mechanics is smaller at the same relative exercise intensity compared with IAT. However, the absolute magnitude (degrees) of LV twist mechanics appears to be associated with the prevailing rate pressure product. Exercise tests that evaluate LV twist mechanics should be standardised by relative exercise intensity and rate pressure product be taken into account when interpreting results. PMID:27100099

  7. Quercetin Suppresses Twist to Induce Apoptosis in MCF-7 Breast Cancer Cells.

    Directory of Open Access Journals (Sweden)

    Santhalakshmi Ranganathan

    Full Text Available Quercetin is a dietary flavonoid which exerts anti-oxidant, anti-inflammatory and anti-cancer properties. In this study, we investigated the anti-proliferative effect of quercetin in two breast cancer cell lines (MCF-7 and MDA-MB-231, which differed in hormone receptor. IC50 value (37μM of quercetin showed significant cytotoxicity in MCF-7 cells, which was not observed in MDA-MB-231 cells even at 100μM of quercetin treatment. To study the response of cancer cells to quercetin, with respect to different hormone receptors, both the cell lines were treated with a fixed concentration (40μM of quercetin. MCF-7 cells on quercetin treatment showed more apoptotic cells with G1 phase arrest. In addition, quercetin effectively suppressed the expression of CyclinD1, p21, Twist and phospho p38MAPK, which was not observed in MDA-MB-231 cells. To analyse the molecular mechanism of quercetin in exerting an apoptotic effect in MCF-7 cells, Twist was over-expressed and the molecular changes were observed after quercetin administration. Quercetin effectively regulated the expression of Twist, in turn p16 and p21 which induced apoptosis in MCF-7 cells. In conclusion, quercetin induces apoptosis in breast cancer cells through suppression of Twist via p38MAPK pathway.

  8. An Analysis of the Linguistic Deviation in Chapter X of Oliver Twist

    Institute of Scientific and Technical Information of China (English)

    刘聪

    2013-01-01

    Charles Dickens is one of the greatest critical realist writers of the Victorian Age. In language, he is often compared with William Shakespeare for his adeptness with the vernacular and large vocabulary. Charles Dickens achieved a recognizable place among English writers through the use of the stylistic features in his fictional language. Oliver Twist is the best representative of Charles Dickens’style, which makes it the most appropriate choice for the present stylistic study on Charles Dickens. No one who has ever read the dehumanizing workhouse scenes of Oliver Twist and the dark, criminal underworld life can forget them. This thesis attempts to investigate Oliver Twist through the approach of modern stylistics, particularly the theory of linguistic devia-tion. This thesis consists of an introduction, the main body and a conclusion. The introduction offers a brief summary of the com-ments on Charles Dickens and Chapter X of Oliver Twist, introduces the newly rising linguistic deviation theories, and brings about the theories on which this thesis settles. The main body explores the deviation effects produced from four aspects: lexical deviation, grammatical deviation, graphological deviation, and semantic deviation. It endeavors to show Dickens ’manipulating language and the effects achieved through this manipulation. The conclusion mainly sums up the previous analysis, and reveals the theme of the novel, positive effect of linguistic deviation and significance of deviation application.

  9. PC Mobile Warrior with a built-in cellular phone; Keitai denwa naizogata PC 'Mobile warrior

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    A PC Mobile Warrior with a built-in cellular phone has been developed from PC Libretto through cooperation with the NTT DoCoMo. The new personal computer incorporates into itself some distinguished mobile PC features such as Wake On Radio and Wake On Ring which are defined by MCPC (Mobile Computing Promotion Consortium). Wake On Radio is a function that activates the PC upon entry into the zone from outside, and Wake On Ring is another function that does the same upon arrival of a phone call. Installed on these lower order functions are an application program for automatic transmission of stored e-mails making use of the former function and another for automatic reception of FAX messages making use of the latter function. (translated by NEDO)

  10. Hilbert's Grand Hotel with a series twist

    Science.gov (United States)

    Wijeratne, Chanakya; Mamolo, Ami; Zazkis, Rina

    2014-08-01

    This paper presents a new twist on a familiar paradox, linking seemingly disparate ideas under one roof. Hilbert's Grand Hotel, a paradox which addresses infinite set comparisons is adapted and extended to incorporate ideas from calculus - namely infinite series. We present and resolve several variations, and invite the reader to explore his or her own variations.

  11. QCD factorization of exclusive processes beyond leading twist: γT*→ρT impact factor with twist three accuracy

    International Nuclear Information System (INIS)

    Anikin, I.V.; Ivanov, D.Yu.; Pire, B.; Szymanowski, L.; Wallon, S.

    2010-01-01

    We describe a consistent approach to factorization of scattering amplitudes for exclusive processes beyond the leading twist approximation. The method involves the Taylor expansion of the scattering amplitude in the momentum space around the dominant light-cone direction and thus naturally introduces an appropriate set of non-perturbative correlators which encode effects not only of the lowest but also of the higher Fock states of the produced particle. The reduction of original set of correlators to a set of independent ones is achieved with the help of equations of motion and invariance of the scattering amplitude under rotation on the light cone. We compare the proposed method with the covariant method formulated in the coordinate space, based on the operator product expansion. We prove the equivalence of two proposed parametrizations of the ρ T distribution amplitudes. As a concrete application, we compute the expressions of the impact factor for the transition of virtual photon to transversally polarised ρ-meson up to the twist 3 accuracy within these two quite different methods and show that they are identical.

  12. PC Pricer

    Data.gov (United States)

    U.S. Department of Health & Human Services — The PC Pricer is a tool used to estimate Medicare PPS payments. The final payment may not be precise to how payments are determined in the Medicare claims processing...

  13. Separation of minimum and higher twist in photoproduction of high-pT mesons

    International Nuclear Information System (INIS)

    Apsimon, R.J.; Flower, P.S.; Hallewell, G.; Morris, J.A.G.; Morris, J.V.; Paterson, C.N.; Sharp, P.H.; Atkinson, M.; Brook, N.; Coyle, P.; Dickinson, B.; Donnachie, A.; Doyle, A.T.; Ellison, R.J.; Foster, J.M.; Hughes-Jones, R.E.; Ibbotson, M.; Kolya, S.D.; Lafferty, G.D.; McCann, H.; McManus, C.; Mercer, D.; Ottewell, P.J.; Reid, D.; Thompson, R.J.; Waterhouse, J.; Barberis, D.; Davenport, M.; Eades, J.; Ingelman, G.; McClatchey, R.; Brodbeck, T.J.; Charity, T.; Clegg, A.B.; Henderson, R.C.W.; Hickman, M.T.; Keemer, N.R.; Newton, D.; O'Connor, A.; Wilson, G.W.; Danaher, S.; Galbraith, W.; Thacker, N.A.; Thompson, L.; Diekmann, B.; Gapp, C.; Gebert, F.; Heinloth, K.; Hoeger, K.C.; Holzkamp, A.; Holzkamp, S.; Jakob, H.P.; Joseph, D.; Kingler, J.; Koersgen, G.; Oedingen, R.; Paul, E.; Rotscheidt, H.; Soeldner-Rembold, S.; Weigend, A.S.

    1991-01-01

    Photo- and hadroproduction data in the beam energy range 65-175 GeV have been studied with a view to isolating higher-twist processes in photoproduction from other point-like and hadron-like contributions. With selection of charged tracks having p T >2 GeV/c and 0.28 F <0.84 indications of a higher twist contribution have been found at a level that is consistent with QCD expectations. (orig.)

  14. 6-mercaptopurine and daunorubicin double drug liposomes-preparation, drug-drug interaction and characterization.

    Science.gov (United States)

    Agrawal, Vineet; Paul, Manash K; Mukhopadhyay, Anup K

    2005-01-01

    This article addresses and investigates the dual incorporation of daunorubicin (DR) and 6-mercaptopurine (6-MP) in liposomes for better chemotherapy. These drugs are potential candidates for interaction due to the quinone (H acceptor) and hydroxyl (H donor) groups on DR and 6-MP, respectively. Interactions between the two drugs in solution were monitored by UV/Vis and fluorescence spectroscopy. Interaction between the two drugs inside the liposomes was evaluated by HPLC (for 6-MP) and by fluorescence spectroscopy (for daunorubicin) after phospholipase-mediated liposome lysis. Our results provide evidence for the lack of interaction between the two drugs in solution and in liposomes. The entrapment efficiencies of 6-MP in the neutral Phosphatidyl choline (PC):Cholesterol (Chol):: 2:1 and anionic PC:Chol:Cardiolipin (CL) :: 4:5:1 single and double drug liposomes were found to be 0.4% and 1.5% (on average), respectively. The entrapment efficiencies of DR in the neutral and anionic double drug liposomes were found to be 55% and 31%, respectively. The corresponding entrapment of daunorubicin in the single drug liposomes was found to be 62% on average. Our thin layer chromatography (TLC) and transmission electron microscopy (TEM) results suggest stability of lipid and liposomes, thus pointing plausible existence of double drug liposomes. Cytotoxicity experiments were performed by using both single drug and double drug liposomes. By comparing the results of phase contrast and fluorescence microscopy, it was observed that the double drug liposomes were internalized in the jurkat and Hut78 (highly resistant cell line) leukemia cells as viewed by the fluorescence of daunorubicin. The cytotoxicity was dose dependent and had shown a synergistic effect when double drug liposome was used.

  15. On reflection algebras and twisted Yangians

    International Nuclear Information System (INIS)

    Doikou, Anastasia

    2005-01-01

    It is well known that integrable models associated to rational R matrices give rise to certain non-Abelian symmetries known as Yangians. Analogously boundary symmetries arise when general but still integrable boundary conditions are implemented, as originally argued by Delius, Mackay, and Short from the field theory point of view, in the context of the principal chiral model on the half-line. In the present study we deal with a discrete quantum mechanical system with boundaries, that is the N site gl(n) open quantum spin chain. In particular, the open spin chain with two distinct types of boundary condition known as soliton preserving and soliton nonpreserving is considered. For both types of boundaries we present a unified framework for deriving the corresponding boundary nonlocal charges directly at the quantum level. The nonlocal charges are simply coproduct realizations of particular boundary quantum algebras called boundary or twisted Yangians, depending on the choice of boundary conditions. Finally, with the help of linear intertwining relations between the solutions of the reflection equation and the generators of the boundary or twisted Yangians we are able to exhibit the exact symmetry of the open spin chain, namely we show that a number of the boundary nonlocal charges are in fact conserved quantities

  16. ELIPGRID-PC: A PC program for calculating hot spot probabilities

    International Nuclear Information System (INIS)

    Davidson, J.R.

    1994-10-01

    ELIPGRID-PC, a new personal computer program has been developed to provide easy access to Singer's 1972 ELIPGRID algorithm for hot-spot detection probabilities. Three features of the program are the ability to determine: (1) the grid size required for specified conditions, (2) the smallest hot spot that can be sampled with a given probability, and (3) the approximate grid size resulting from specified conditions and sampling cost. ELIPGRID-PC also provides probability of hit versus cost data for graphing with spread-sheets or graphics software. The program has been successfully tested using Singer's published ELIPGRID results. An apparent error in the original ELIPGRID code has been uncovered and an appropriate modification incorporated into the new program

  17. Experimental studies on heat transfer and thermal performance characteristics of thermosyphon solar water heating system with helical and Left-Right twisted tapes

    International Nuclear Information System (INIS)

    Jaisankar, S.; Radhakrishnan, T.K.; Sheeba, K.N.

    2011-01-01

    Research highlights: → Conventional solar heaters are inefficient due to poor convective heat transfer. → Twisted tapes improve the heat transfer rate in solar water heater system. → Increase in outlet water temperature by 15 o C through the use of twisted tapes. →Thermal performance of twisted tape collector is 19% more than plain tube system. → Reduces collector area (0.6 m 2 ) whereas area for conventional collector is 1 m 2 . -- Abstract: Experimental investigation of heat transfer, friction factor and thermal performance of thermosyphon solar water heater system fitted with helical and Left-Right twist of twist ratio 3 has been performed and presented. The helical twisted tape induces swirl flow inside the riser tubes unidirectional over the length. But, in Left-Right system the swirl flow is bidirectional which increases the heat transfer and pressure drop when compared to the helical system. The experimental heat transfer and friction factors characteristics are validated with theoretical equations and the deviation falls with in the acceptable limits. The results show that heat transfer enhancement in twisted tape collector is higher than the plain tube collector. Compared to helical and Left-Right twisted tape system of same twist ratio 3, maximum thermal performance is obtained for Left-Right twisted tape collector with increase in solar intensity.

  18. Static-light meson masses from twisted mass lattice QCD

    International Nuclear Information System (INIS)

    Jansen, Karl; Michael, Chris; Shindler, Andrea; Wagner, Marc

    2008-08-01

    We compute the static-light meson spectrum using two-flavor Wilson twisted mass lattice QCD. We have considered five different values for the light quark mass corresponding to 300 MeV PS S mesons. (orig.)

  19. 3-sphere fibrations: a tool for analyzing twisted materials in condensed matter

    International Nuclear Information System (INIS)

    Sadoc, J F; Charvolin, J

    2009-01-01

    Chiral molecules, when densely packed in soft condensed matter or biological materials, build organizations which are most often spontaneously twisted. The crystals of 'blue' phases formed by small mesogenic molecules demonstrate the structural importance of such a twist or torsion, and its presence was also recently observed in finite toroidal aggregates formed by long DNA molecules. The formation of these organizations is driven by the fact that compactness, which tends to align the molecules, enters into conflict with torsion, which tends to disrupt this alignment. This conflict of topological nature, or frustration, arises because of the flatness of the Euclidean space, but does not exist in the curved space of the 3-sphere where particular lines, its fibres, can be drawn which are parallel and nevertheless twisted. As these fibrations conciliate compactness and torsion, they can be used as geometrical templates for the analysis of organizations in the Euclidean space. We describe these fibrations, with a particular emphasis on their torsion.

  20. Electronic structure and optical properties of twisted bilayer graphene calculated via time evolution of states in real space

    Science.gov (United States)

    Le, H. Anh; Do, V. Nam

    2018-03-01

    We investigate the electronic and optical properties of twisted bilayer graphene with arbitrary twist angles θ . Our results are based on a method of evolving in time quantum states in lattice space. We propose an efficient scheme of sampling lattice nodes that helps to reduce significantly computational cost, particularly for tiny twist angles. We demonstrate the continuous variation of the density of states and the optical conductivity with respect to the twist angle. It indicates that the commensurability between the two graphene layers does not play an essential role in governing the electronic and optical properties. We point out that, for the twist angles roughly in the range 0 .1∘energy exhibits the typical W shape with a small peak locating at the Fermi energy. This peak is formed as the merging of two van Hove peaks and reflects the appearance of states strongly localized in the AA-like region of moiré zones. When decreasing the twist angle to zero, the W shape is gradually transformed to the U shape, which is seen as the behavior of the density of states in the limit of θ →0∘ .

  1. Line bundle twisted chiral de Rham complex and bound states of D-branes on toric manifolds

    International Nuclear Information System (INIS)

    Parkhomenko, S.E.

    2014-01-01

    In this note we calculate elliptic genus in various examples of twisted chiral de Rham complex on two-dimensional toric compact manifolds and Calabi–Yau hypersurfaces in toric manifolds. At first the elliptic genus is calculated for the line bundle twisted chiral de Rham complex on a compact smooth toric manifold and K3 hypersurface in P 3 . Then we twist chiral de Rham complex by sheaves localized on positive codimension submanifolds in P 2 and calculate in each case the elliptic genus. In the last example the elliptic genus of chiral de Rham complex on P 2 twisted by SL(N) vector bundle with instanton number k is calculated. In all the cases considered we find the infinite tower of open string oscillator contributions and identify directly the open string boundary conditions of the corresponding bound state of D-branes

  2. Partially coherent twisted states in arrays of coupled phase oscillators

    Energy Technology Data Exchange (ETDEWEB)

    Omel' chenko, Oleh E.; Wolfrum, Matthias [Weierstrass Institute, Mohrenstrasse 39, 10117 Berlin (Germany); Laing, Carlo R. [INMS, Massey University, Private Bag 102-904 NSMC, Auckland (New Zealand)

    2014-06-15

    We consider a one-dimensional array of phase oscillators with non-local coupling and a Lorentzian distribution of natural frequencies. The primary objects of interest are partially coherent states that are uniformly “twisted” in space. To analyze these, we take the continuum limit, perform an Ott/Antonsen reduction, integrate over the natural frequencies, and study the resulting spatio-temporal system on an unbounded domain. We show that these twisted states and their stability can be calculated explicitly. We find that stable twisted states with different wave numbers appear for increasing coupling strength in the well-known Eckhaus scenario. Simulations of finite arrays of oscillators show good agreement with results of the analysis of the infinite system.

  3. Partially coherent twisted states in arrays of coupled phase oscillators

    International Nuclear Information System (INIS)

    Omel'chenko, Oleh E.; Wolfrum, Matthias; Laing, Carlo R.

    2014-01-01

    We consider a one-dimensional array of phase oscillators with non-local coupling and a Lorentzian distribution of natural frequencies. The primary objects of interest are partially coherent states that are uniformly “twisted” in space. To analyze these, we take the continuum limit, perform an Ott/Antonsen reduction, integrate over the natural frequencies, and study the resulting spatio-temporal system on an unbounded domain. We show that these twisted states and their stability can be calculated explicitly. We find that stable twisted states with different wave numbers appear for increasing coupling strength in the well-known Eckhaus scenario. Simulations of finite arrays of oscillators show good agreement with results of the analysis of the infinite system

  4. Construction and expression of secreting type human TRAIL gene vector mediated by hypoxia/radiation double sensitive promoter

    International Nuclear Information System (INIS)

    Yang Yanming; Jia Xiaojing; Qu Yaqin; Li Yanbo

    2009-01-01

    Objective: To construct secreting type human TRAIL (shTRAIL) gene vector pcDNA3.1-HRE/Egr1-shTRAIL mediated by hypoxia/radiation double sensitive promoter, and observe the effect of hypoxia and radiation on shTRAIL. Methods: HRE upper and lower strands were gotten by chemical synthesis, double strands HRE was gotten by PCR; pMD19T-Egr1 was digested by Sac I and Hind III, then Egr1 was obtained, pshuttle-shTRAIL was digested by Kpn I and BamH I, then shTRAIL was obtained; HRE/Egr1 double sensitive promoter mediated shTRAIL expression vector pcDNA3.1-HRE/Egr1-shTRAIL was constructed by gene recombination technique, it was identified correctly by enzyme digestion, PCR and sequencing. A549 cells were divided into normal, hypoxia (0.1%), irradiation (6 Gy) and hypoxia + irradiation groups. Results: After enzyme digestion by BamH I and Sma I, the fragments which lengths were 1284 bp and 4 998 bp, 2 292 bp and 3 990 bp were obtained; the vector was amplified by PCR with Egr1 and shTRAIL primer, the products which lengthens were 469 bp and 820 bp were obtained; pcDNA3.1-HRE/Egr1-shTRAIL was sequenced, the result was same to designed, this demonstrated that the construction was right. The vectors were transfected into A549 cells of adenocarcinoma of lung, the expression levels of shTRAIL mRNA and protein were increased after treated with hypoxia and radiation, it had statistically significant differences compared with normal group (P<0.05), and when they were combinated, the effect was more obvious. Conclusion: Secreting type human TRAIL gene vector pcDNA3.1-HRE/Egr1-shTRAIL mediated by hypoxia/radiation double sensitive promoter is constructed successfully, and hypoxia and radiation could increase the expression of TRAIL, and they have synergetic effect. (authors)

  5. High performance electrochemical and electrothermal artificial muscles from twist-spun carbon nanotube yarn

    Science.gov (United States)

    Lee, Jae Ah; Baughman, Ray H.; Kim, Seon Jeong

    2015-04-01

    High performance torsional and tensile artificial muscles are described, which utilize thermally- or electrochemically-induced volume changes of twist-spun, guest-filled, carbon nanotube (CNT) yarns. These yarns were prepared by incorporating twist in carbon nanotube sheets drawn from spinnable CNT forests. Inserting high twist into the CNT yarn results in yarn coiling, which can dramatically amplify tensile stroke and work capabilities compared with that for the non-coiled twisted yarn. When electrochemically driven in a liquid electrolyte, these artificial muscles can generate a torsional rotation per muscle length that is over 1000 times higher than for previously reported torsional muscles. All-solid-state torsional electrochemical yarn muscles have provided a large torsional muscle stroke (53° per mm of yarn length) and a tensile stroke of up to 1.3% when lifting loads that are ~25 times heavier than can be lifted by the same diameter human skeletal muscle. Over a million torsional and tensile actuation cycles have been demonstrated for thermally powered CNT hybrid yarns muscles filled with paraffin wax, wherein a muscle spins a rotor at an average 11,500 revolutions/minute or delivers 3% tensile contraction at 1200 cycles/minute. At lower actuation rates, these thermally powered muscles provide tensile strokes of over 10%.

  6. PrPC from stem cells to cancer

    Directory of Open Access Journals (Sweden)

    Séverine eMartin-Lannerée

    2014-09-01

    Full Text Available The cellular prion protein PrPC was initially discovered as the normal counterpart of the pathological scrapie prion protein PrPSc, the main component of the infectious agent of Transmissible Spongiform Encephalopathies. While clues as to the physiological function of this ubiquitous protein were greatly anticipated from the development of knock-out animals, PrP-null mice turned out to be viable and to develop without major phenotypic abnormalities. Notwithstanding, the discovery that hematopoietic stem cells from PrP-null mice have impaired long-term repopulating potential has set the stage for investigating into the role of PrPC in stem cell biology. A wealth of data have now exemplified that PrPC is expressed in distinct types of stem cells and regulates their self-renewal as well as their differentiation potential. A role for PrPC in the fate restriction of embryonic stem cells has further been proposed. Paralleling these observations, an overexpression of PrPC has been documented in various types of tumours. In line with the contribution of PrPC to stemness and to the proliferation of cancer cells, PrPC was recently found to be enriched in subpopulations of tumour-initiating cells. In the present review, we summarize the current knowledge of the role played by PrPC in stem cell biology and discuss how the subversion of its function may contribute to cancer progression.

  7. Nonsnaking doubly diffusive convectons and the twist instability

    Energy Technology Data Exchange (ETDEWEB)

    Beaume, Cédric, E-mail: ced.beaume@gmail.com; Knobloch, Edgar, E-mail: knobloch@berkeley.edu [Department of Physics, University of California, Berkeley, California 94720 (United States); Bergeon, Alain, E-mail: alain.bergeon@imft.fr [Université de Toulouse, INPT, UPS, IMFT (Institut de Mécanique des Fluides de Toulouse), Allée Camille Soula, F-31400 Toulouse, France and CNRS, IMFT, F-31400 Toulouse (France)

    2013-11-15

    Doubly diffusive convection in a three-dimensional horizontally extended domain with a square cross section in the vertical is considered. The fluid motion is driven by horizontal temperature and concentration differences in the transverse direction. When the buoyancy ratio N = −1 and the Rayleigh number is increased the conduction state loses stability to a subcritical, almost two-dimensional roll structure localized in the longitudinal direction. This structure exhibits abrupt growth in length near a particular value of the Rayleigh number but does not snake. Prior to this filling transition the structure becomes unstable to a secondary twist instability generating a pair of stationary, spatially localized zigzag states. In contrast to the primary branch these states snake as they grow in extent and eventually fill the whole domain. The origin of the twist instability and the properties of the resulting localized structures are investigated for both periodic and no-slip boundary conditions in the extended direction.

  8. The ρ-meson longitudinal leading-twist distribution amplitude

    Directory of Open Access Journals (Sweden)

    Hai-Bing Fu

    2014-11-01

    Full Text Available In the present paper, we suggest a convenient model for the vector ρ-meson longitudinal leading-twist distribution amplitude ϕ2;ρ‖, whose distribution is controlled by a single parameter B2;ρ‖. By choosing proper chiral current in the correlator, we obtain new light-cone sum rules (LCSR for the B→ρ TFFs A1, A2 and V, in which the δ1-order ϕ2;ρ‖ provides dominant contributions. Then we make a detailed discussion on the ϕ2;ρ‖ properties via those B→ρ TFFs. A proper choice of B2;ρ‖ can make all the TFFs agree with the lattice QCD predictions. A prediction of |Vub| has also been presented by using the extrapolated TFFs, which indicates that a larger B2;ρ‖ leads to a larger |Vub|. To compare with the BABAR data on |Vub|, the longitudinal leading-twist DA ϕ2;ρ‖ prefers a doubly-humped behavior.

  9. On the restoration of supersymmetry in twisted two-dimensional lattice Yang-Mills theory

    International Nuclear Information System (INIS)

    Catterall, Simon

    2007-01-01

    We study a discretization of N = 2 super Yang-Mills theory which possesses a single exact supersymmetry at non-zero lattice spacing. This supersymmetry arises after a reformulation of the theory in terms of twisted fields. In this paper we derive the action of the other twisted supersymmetries on the component fields and study, using Monte Carlo simulation, a series of corresponding Ward identities. Our results for SU(2) and SU(3) support a restoration of these additional supersymmetries without fine tuning in the infinite volume continuum limit. Additionally we present evidence supporting a restoration of (twisted) rotational invariance in the same limit. Finally we have examined the distribution of scalar field eigenvalues and find evidence for power law tails extending out to large eigenvalue. We argue that these tails indicate that the classical moduli space does not survive in the quantum theory

  10. Performance Assessment in a Heat Exchanger Tube with Opposite/Parallel Wing Twisted Tapes

    Directory of Open Access Journals (Sweden)

    S. Eiamsa-ard

    2015-02-01

    Full Text Available The thermohydraulic performance in a tube containing a modified twisted tape with alternate-axes and wing arrangements is reported. This work aims to investigate the effects of wing arrangements (opposite (O and parallel (P wings at different wing shapes (triangle (Tri, rectangular (Rec, and trapezoidal (Tra wings and on the thermohydraulic performance characteristics. The obtained results show that wing twisted tapes with all wing shape arrangements (O-Tri/O-Rec/O-Tra/P-Tri/P-Rec/P-Tra give superior thermohydraulic performance and heat transfer rate to the typical twisted tape. In addition, the tapes with opposite wing arrangement of O-Tra, O-Rec, and O-Tri give superior thermohydraulic performances to those with parallel wing arrangement of P-Tra, P-Rec, and P-Tri around 2.7%, 3.5%, and 3.2%, respectively.

  11. The readout performance evaluation of PowerPC

    International Nuclear Information System (INIS)

    Chu Yuanping; Zhang Hongyu; Zhao Jingwei; Ye Mei; Tao Ning; Zhu Kejun; Tang Suqiu; Guo Yanan

    2003-01-01

    PowerPC, as a powerful low-cost embedded computer, is one of the very important research objects in recent years in the project of BESIII data acquisition system. The researches on the embedded system and embedded computer have achieved many important results in the field of High Energy Physics especially in the data acquisition system. The one of the key points to design an acquisition system using PowerPC is to evaluate the readout ability of PowerPC correctly. The paper introduce some tests for the PowerPC readout performance. (authors)

  12. Design of twisted tape turbulator at different entrance angle for heat transfer enhancement in a solar heater

    Directory of Open Access Journals (Sweden)

    Suvanjan Bhattacharyya

    2018-03-01

    Full Text Available Numerical investigation of heat transfer characteristics in a tube fitted with inserted twisted tape swirl generator is performed. The twisted tapes are separately inserted from the tube wall. The configuration parameters include the, entrance angle (α and pitch (H. Investigations have been done in the range of α = 180°, 160° and 140° with Reynolds number varying between 100 and 20,000. In this paper, transition – SST model which can predict the transition of flow regime from laminar through intermittent to turbulent has been utilized for numerical simulations. The computational results are in good agreement with experimental data. The results show that higher entrance angle yields a higher heat transfer value. The using of single twist twisted tape supplies considerable increase on heat transfer and pressure drop when compared with the conventional twisted tapes. A large data set has been generated for heat transfer and thermal-hydraulic performance which is useful for the design of solar thermal heaters and heat exchangers.

  13. Integral Twist Actuation of Helicopter Rotor Blades for Vibration Reduction

    Science.gov (United States)

    Shin, SangJoon; Cesnik, Carlos E. S.

    2001-01-01

    Active integral twist control for vibration reduction of helicopter rotors during forward flight is investigated. The twist deformation is obtained using embedded anisotropic piezocomposite actuators. An analytical framework is developed to examine integrally-twisted blades and their aeroelastic response during different flight conditions: frequency domain analysis for hover, and time domain analysis for forward flight. Both stem from the same three-dimensional electroelastic beam formulation with geometrical-exactness, and axe coupled with a finite-state dynamic inflow aerodynamics model. A prototype Active Twist Rotor blade was designed with this framework using Active Fiber Composites as the actuator. The ATR prototype blade was successfully tested under non-rotating conditions. Hover testing was conducted to evaluate structural integrity and dynamic response. In both conditions, a very good correlation was obtained against the analysis. Finally, a four-bladed ATR system is built and tested to demonstrate its concept in forward flight. This experiment was conducted at NASA Langley Tansonic Dynamics Tunnel and represents the first-of-a-kind Mach-scaled fully-active-twist rotor system to undergo forward flight test. In parallel, the impact upon the fixed- and rotating-system loads is estimated by the analysis. While discrepancies are found in the amplitude of the loads under actuation, the predicted trend of load variation with respect to its control phase correlates well. It was also shown, both experimentally and numerically, that the ATR blade design has the potential for hub vibratory load reduction of up to 90% using individual blade control actuation. Using the numerical framework, system identification is performed to estimate the harmonic transfer functions. The linear time-periodic system can be represented by a linear time-invariant system under the three modes of blade actuation: collective, longitudinal cyclic, and lateral cyclic. A vibration

  14. Implementasi Penggunaan Smartphone Android untuk Control PC (Personal Computer

    Directory of Open Access Journals (Sweden)

    Imam Solikin

    2018-05-01

    Full Text Available The purpose of this research is to simplify the control of personal computer (PC such as control pointer, keyboard control and make it easier to do the presentation by controlling the slide remotely using smartphone through wifi connections facility. The smartphone is a multimedia phone that combines PC functionality with microprocessor, memory, and built-in modem to produce smart smartphone gadgets. Problems that occur when performing a presentation such as PC control, control pointer and keyboard control for input should be close to the PC so it is less than optimal in explaining the material. The model used in implementing the use of Android Smartphone for PC control is a conceptual model consisting of several stages: potential and problems, data collection, system testing, test results, and system implementation or implementation. From the results of PC control research can be done by connecting the Smartphone with a PC via wifi network so that PC can be controlled remotely. PC control application is an application that can control PC remotely connected via wifi network connection. Benefits derived from this research make it easy to mengedalikan PC remotely such as facilitate in the percentage and control pointer and control Keyboard for input process.

  15. Structures of Highly Twisted Amides Relevant to Amide N-C Cross-Coupling: Evidence for Ground-State Amide Destabilization.

    Science.gov (United States)

    Pace, Vittorio; Holzer, Wolfgang; Meng, Guangrong; Shi, Shicheng; Lalancette, Roger; Szostak, Roman; Szostak, Michal

    2016-10-04

    Herein, we show that acyclic amides that have recently enabled a series of elusive transition-metal-catalyzed N-C activation/cross-coupling reactions are highly twisted around the N-C(O) axis by a new destabilization mechanism of the amide bond. A unique effect of the N-glutarimide substituent, leading to uniformly high twist (ca. 90°) irrespective of the steric effect at the carbon side of the amide bond has been found. This represents the first example of a twisted amide that does not bear significant steric hindrance at the α-carbon atom. The (15) N NMR data show linear correlations between electron density at nitrogen and amide bond twist. This study strongly supports the concept of amide bond ground-state twist as a blueprint for activation of amides toward N-C bond cleavage. The new mechanism offers considerable opportunities for organic synthesis and biological processes involving non-planar amide bonds. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Design of a Tapered and Twisted Blade for the NREL Combined Experiment Rotor; TOPICAL

    International Nuclear Information System (INIS)

    Giguere, P.; Selig, M. S.

    1999-01-01

    A tapered/twisted blade was designed to operate on the Combined Experiment Rotor (CER) of the National Renewable Energy Lab., which is a stall-regulated downwind wind turbine having a rated power of 20 kilowatt. The geometry of the new blade set was optimized based on annual energy production subject to the constraints imposed on the design. These constraints were mainly related to scientific needs for fundamental research in rotor aerodynamics. A trade-off study was conducted to determine the effect of the different design constraints. Based on the results of this study, which considered nonlinear twist and taper distributions as well as the NREL S809, S814, S822 and S823 airfoils, a blade having a linear taper and a nonlinear twist distribution that uses the S809 airfoil from root to tip was selected. This blade configuration is the logical continuation of the previous constant-chord twisted and untwisted blade sets and will facilitate comparison with those earlier blades. Despite th e design constraints based on scientific needs, the new blade is more representative of commercial blades than the previous blade sets

  17. Installation and implementation of PC COSYMA; PC COSYMAn kaeyttoeoenotto ja soveltaminen

    Energy Technology Data Exchange (ETDEWEB)

    Rossi, J [VTT Energy, Espoo (Finland). Nuclear Energy

    1995-12-01

    COSYMA is a probabilistic reactor accident consequence assessment model developed in the 1980`s by the research institutes of the EC countries, primarily by NRPB and KfK. In 1993 a simplified version of the program was released to be implemented on a PC. In the study the PC COSYMA program was applied to calculate as the end points nuclide concentrations, doses received, numbers of health effects, areas affected by countermeasures and other results related to countermeasure strategies. Some results are compared with the results obtained by the ARANO program developed by VTT Energy (Technical Research Centre of Finland) to quarantee proper interpretation of the application. (15 refs.).

  18. Twisted-Light-Ion Interaction: The Role of Longitudinal Fields

    Science.gov (United States)

    Quinteiro, G. F.; Schmidt-Kaler, Ferdinand; Schmiegelow, Christian T.

    2017-12-01

    The propagation of light beams is well described using the paraxial approximation, where field components along the propagation direction are usually neglected. For strongly inhomogeneous or shaped light fields, however, this approximation may fail, leading to intriguing variations of the light-matter interaction. This is the case of twisted light having opposite orbital and spin angular momenta. We compare experimental data for the excitation of a quadrupole transition in a single trapped 40Ca+ ion from Schmiegelow et al. [Nat. Commun. 7, 12998 (2016), 10.1038/ncomms12998] with a complete model where longitudinal components of the electric field are taken into account. Our model matches the experimental data and excludes by 11 standard deviations the approximation of a complete transverse field. This demonstrates the relevance of all field components for the interaction of twisted light with matter.

  19. Spontaneous formation of non-uniform double helices for elastic rods under torsion

    International Nuclear Information System (INIS)

    Li, Hongyuan; Zhao, Shumin; Xia, Minggang; He, Siyu; Yang, Qifan; Yan, Yuming; Zhao, Hanqiao

    2017-01-01

    The spontaneous formation of double helices for filaments under torsion is common and significant. For example, the research on the supercoiling of DNA is helpful for understanding the replication and transcription of DNA. Similar double helices can appear in carbon nanotube yarns, cables, telephone wires and so forth. We noticed that non-uniform double helices can be produced due to the surface friction induced by the self-contact. Therefore an ideal model was presented to investigate the formation of double helices for elastic rods under torque. A general equilibrium condition which is valid for both the smooth surface and the rough surface situations is derived by using the variational method. By adding further constraints, the smooth and rough surface situations are investigated in detail respectively. Additionally, the model showed that the specific process of how to twist and slack the rod can determine the surface friction and hence influence the configuration of the double helix formed by rods with rough surfaces. Based on this principle, a method of manufacturing double helices with designed configurations was proposed and demonstrated. Finally, experiments were performed to verify the model and the results agreed well with the theory. - Highlights: • An ideal model is conceived to investigate the spontaneous formation of double helices for rods under torsion. • Variational method is used to obtain a universal result for the double helix formation process • Self-contact and surface friction is considered to analyze the non-uniform double helix. • A novel method of producing double helix with arbitrary configuration is proposed and demonstrated. • The experiment results agree well with the theory.

  20. Spontaneous formation of non-uniform double helices for elastic rods under torsion

    Energy Technology Data Exchange (ETDEWEB)

    Li, Hongyuan [Department of Applied Physics, School of Science, Xi' an Jiaotong University, Shaanxi 710049 (China); Zhao, Shumin, E-mail: zhaosm@mail.xjtu.edu.cn [Department of Applied Physics, School of Science, Xi' an Jiaotong University, Shaanxi 710049 (China); Xia, Minggang [Department of Optical Information Science and Technology, School of Science, Xi' an Jiaotong University, 710049 (China); Laboratory of Nanostructure and Physics Properties, School of Science, Xi' an Jiaotong University, 710049 (China); He, Siyu [Department of Applied Physics, School of Science, Xi' an Jiaotong University, Shaanxi 710049 (China); Yang, Qifan [Department of Biomedical Engineering, School of Life Science and Technology, Xi' an Jiaotong University, Shaanxi 710049 (China); Yan, Yuming [Department of Electrical Engineering and Automation, School of Electrical Engineering, Xi' an Jiaotong University, Shaanxi 710049 (China); Zhao, Hanqiao [Department of Biomedical Engineering, School of Life Science and Technology, Xi' an Jiaotong University, Shaanxi 710049 (China)

    2017-02-19

    The spontaneous formation of double helices for filaments under torsion is common and significant. For example, the research on the supercoiling of DNA is helpful for understanding the replication and transcription of DNA. Similar double helices can appear in carbon nanotube yarns, cables, telephone wires and so forth. We noticed that non-uniform double helices can be produced due to the surface friction induced by the self-contact. Therefore an ideal model was presented to investigate the formation of double helices for elastic rods under torque. A general equilibrium condition which is valid for both the smooth surface and the rough surface situations is derived by using the variational method. By adding further constraints, the smooth and rough surface situations are investigated in detail respectively. Additionally, the model showed that the specific process of how to twist and slack the rod can determine the surface friction and hence influence the configuration of the double helix formed by rods with rough surfaces. Based on this principle, a method of manufacturing double helices with designed configurations was proposed and demonstrated. Finally, experiments were performed to verify the model and the results agreed well with the theory. - Highlights: • An ideal model is conceived to investigate the spontaneous formation of double helices for rods under torsion. • Variational method is used to obtain a universal result for the double helix formation process • Self-contact and surface friction is considered to analyze the non-uniform double helix. • A novel method of producing double helix with arbitrary configuration is proposed and demonstrated. • The experiment results agree well with the theory.

  1. Adaptive super-twisting sliding mode control for a three-phase single-stage grid-connected differential boost inverter based photovoltaic system.

    Science.gov (United States)

    Pati, Akshaya K; Sahoo, N C

    2017-07-01

    This paper presents an adaptive super-twisting sliding mode control (STC) along with double-loop control for voltage tracking performance of three-phase differential boost inverter and DC-link capacitor voltage regulation in grid-connected PV system. The effectiveness of the proposed control strategies are demonstrated under realistic scenarios such as variations in solar insolation, load power demand, grid voltage, and transition from grid-connected to standalone mode etc. Additional supplementary power quality control functions such as harmonic compensation, and reactive power management are also investigated with the proposed control strategy. The results are compared with conventional proportional-integral controller, and PWM sliding mode controller. The system performance is evaluated in simulation and in real-time. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

  2. PC based controlled potential coulometric titrator for quantitative analysis of nuclear materials

    International Nuclear Information System (INIS)

    Manna, A.; Moorthy, A.D.; Bhogale, R.G.

    2001-01-01

    With increased requirements for process control and accountability of nuclear materials in plutonium reprocessing plants, the PC based controlled potential coulometric titrator was developed which has the capability of automatic quantitative analysis of the samples. The instruments based on electromechanical methods, incorporates an electronic potentiostat, a digital coulometer with wide dynamic range and a PC with a control interface card. The potentiostat is required to control the potential at the working electrode surface as per predetermined controlled voltage with respect to a reference electrode under wide variations in the conductivity and double layer capacitance of the electrochemical cell. The digital coulometer precisely measures the amount of electronic charge taking part in the electrochemical reactions of interest. The software has the facility to carry out three different types of analysis, i.e., primary coulometry, secondary coulometry and coulogram curve tracing. Due to complete analysis of the samples under program control, the human related errors are minimized and a better precision in the results are obtained. It has been possible to obtain an overall precession of better than +/- 0.3% in the determination of plutonium using the instrument. (author)

  3. String theory flux vacua on twisted tori and generalized complex geometry

    International Nuclear Information System (INIS)

    Andriot, David

    2010-01-01

    This thesis is devoted to the study of flux vacua of string theory, with the ten-dimensional space-time split into a four-dimensional maximally symmetric space-time, and a six-dimensional internal manifold M, taken to be a solv-manifold (twisted torus). Such vacua are of particular interest when trying to relate string theory to supersymmetric (SUSY) extensions of the standard model of particles, or to cosmological models. For SUSY solutions of type II supergravities, allowing for fluxes on M helps to solve the moduli problem. Then, a broader class of manifolds than just the Calabi-Yau can be considered for M, and a general characterization is given in terms of Generalized Complex Geometry: M has to be a Generalized Calabi-Yau (GCY). A subclass of solv-manifolds have been proven to be GCY, so we look for solutions with such M. To do so, we use an algorithmic resolution method. Then we focus on specific new solutions: those admitting an intermediate SU(2) structure. A transformation named the twist is then discussed. It relates solutions on torus to solutions on solv-manifolds. Working out constraints on the twist to generate solutions, we can relate known solutions, and find a new one. We also use the twist to relate flux vacua of heterotic string. Finally we consider ten-dimensional de Sitter solutions. Looking for such solutions is difficult, because of several problems among which the breaking of SUSY. We propose an Ansatz for SUSY breaking sources which helps to overcome these difficulties. We give an explicit solution on a solv-manifold, and discuss partially its four-dimensional stability. (author)

  4. Vacuum expectation value of twist fields

    Science.gov (United States)

    Belitsky, A. V.

    2017-09-01

    Twist fields emerge in a number of physical applications ranging from entanglement entropy to scattering amplitudes in four-dimensional gauge theories. In this work, their vacuum expectation values are studied in the path integral framework. By performing a gauge transformation, their correlation functions are reduced to field theory of matter fields in external Aharonov-Bohm vortices. The resulting functional determinants are then analyzed within the zeta-function regularization for the spectrum of Bessel zeros, and concise formulas are derived.

  5. Chiral Tunnelling in Twisted Graphene Bilayer

    OpenAIRE

    He, Wen-Yu; Chu, Zhao-Dong; He, Lin

    2013-01-01

    The perfect transmission in graphene monolayer and the perfect reflection in Bernal graphene bilayer for electrons incident in the normal direction of a potential barrier are viewed as two incarnations of the Klein paradox. Here we show a new and unique incarnation of the Klein paradox. Owing to the different chiralities of the quasiparticles involved, the chiral fermions in twisted graphene bilayer shows adjustable probability of chiral tunnelling for normal incidence: they can be changed fr...

  6. PC application in DIII-D neutral beam operation

    International Nuclear Information System (INIS)

    Gladd, A.S.

    1986-01-01

    An IBM PC/AT has been implemented to improve operation of the DIII-D neutral beams. The PC system provides centralization of all beam data with reasonable access for online shot-to-shot control and analysis. The PC hardware was configured to interface all four neutral beam host mini-computers, support multi-tasking, and provide storage for approximately one month's accumulation of beam data. The PC software is composed of commercial packages used for performance and statistical analysis (i.e. LOTUS 123, PC PLOT, etc.) host communications software (i.e. PCLINK, KERMIT, etc.) and applications developed software utilizing FORTRAN and BASIC. The objectives of this paper are to describe the implementation of the PC system, the methods of integrating the various software packages, and the scenario for online control and analysis

  7. Stretchable, Twisted Conductive Microtubules for Wearable Computing, Robotics, Electronics, and Healthcare.

    Science.gov (United States)

    Do, Thanh Nho; Visell, Yon

    2017-05-11

    Stretchable and flexible multifunctional electronic components, including sensors and actuators, have received increasing attention in robotics, electronics, wearable, and healthcare applications. Despite advances, it has remained challenging to design analogs of many electronic components to be highly stretchable, to be efficient to fabricate, and to provide control over electronic performance. Here, we describe highly elastic sensors and interconnects formed from thin, twisted conductive microtubules. These devices consist of twisted assemblies of thin, highly stretchable (>400%) elastomer tubules filled with liquid conductor (eutectic gallium indium, EGaIn), and fabricated using a simple roller coating process. As we demonstrate, these devices can operate as multimodal sensors for strain, rotation, contact force, or contact location. We also show that, through twisting, it is possible to control their mechanical performance and electronic sensitivity. In extensive experiments, we have evaluated the capabilities of these devices, and have prototyped an array of applications in several domains of stretchable and wearable electronics. These devices provide a novel, low cost solution for high performance stretchable electronics with broad applications in industry, healthcare, and consumer electronics, to emerging product categories of high potential economic and societal significance.

  8. QCD factorization of exclusive processes beyond leading twist: gamma{sub T}*->rho{sub T} impact factor with twist three accuracy

    Energy Technology Data Exchange (ETDEWEB)

    Anikin, I.V. [Bogoliubov Laboratory of Theoretical Physics, JINR, 141980 Dubna (Russian Federation); Ivanov, D.Yu. [Sobolev Institute of Mathematics, 630090 Novosibirsk (Russian Federation); Pire, B., E-mail: pire@cpht.polytechnique.f [CPHT, Ecole Polytechnique, CNRS, 91128 Palaiseau Cedex (France); Szymanowski, L. [Soltan Institute for Nuclear Studies, PL-00-681 Warsaw (Poland); Wallon, S. [LPT, Universite Paris-Sud, CNRS, 91405 Orsay (France); UPMC Univ. Paris 06, faculte de physique, 4 place Jussieu, 75252 Paris Cedex 05 (France)

    2010-03-21

    We describe a consistent approach to factorization of scattering amplitudes for exclusive processes beyond the leading twist approximation. The method involves the Taylor expansion of the scattering amplitude in the momentum space around the dominant light-cone direction and thus naturally introduces an appropriate set of non-perturbative correlators which encode effects not only of the lowest but also of the higher Fock states of the produced particle. The reduction of original set of correlators to a set of independent ones is achieved with the help of equations of motion and invariance of the scattering amplitude under rotation on the light cone. We compare the proposed method with the covariant method formulated in the coordinate space, based on the operator product expansion. We prove the equivalence of two proposed parametrizations of the rho{sub T} distribution amplitudes. As a concrete application, we compute the expressions of the impact factor for the transition of virtual photon to transversally polarised rho-meson up to the twist 3 accuracy within these two quite different methods and show that they are identical.

  9. Twisted traces of quantum intertwiners and quantum dynamical R-matrices corresponding to generalized Belavin-Drinfeld triples

    International Nuclear Information System (INIS)

    Etingof, P.; Massachusetts Inst. of Tech., Cambridge, MA; Schiffmann, O.

    2001-01-01

    We consider weighted traces of products of intertwining operators for quantum groups U q (g), suitably twisted by a ''generalized Belavin-Drinfeld triple''. We derive two commuting sets of difference equations - the (twisted) Macdonald-Ruijsenaars system and the (twisted) quantum Knizhnik-Zamolodchikov-Bernard (qKZB) system. These systems involve the nonstandard quantum R-matrices defined in a previous joint work with T. Schedler (2000). When the generalized Belavin-Drinfeld triple comes from an automorphism of the Lie algebra g, we also derive two additional sets of difference equations, the dual Macdonald-Ruijsenaars system and the dual qKZB equations. (orig.)

  10. Influence of twisted tape turbulence promoter on fouling reduction in microfiltration of milk proteins

    Directory of Open Access Journals (Sweden)

    Popović Svetlana S.

    2011-01-01

    Full Text Available Membrane filtration has become one of the major technologies in the food industry. It is widely applied in the dairy industry, and it is mostly used for the concentration and fractionation of milk proteins and for the whey processing. Of all pressure driven membrane processes, ultrafiltration is the most widely used. The major disadvantage of pressure driven membrane processes is severe fouling of membrane during filtration particularly when the fluids containing proteins are processed. Fouling with proteins is complex phenomenon because it occurs at the membrane surface as well as in the pores of membrane, and depends on the operating conditions and on the interactions of proteins and membrane material. In order to reduce fouling of the membrane different techniques have been developed, and one of them relies on the changing of the hydrodynamic conditions in the membrane or module. In this study, influence of twisted tape turbulence promoters on the fouling reduction in cross-flow microfiltration of skim milk was investigated. Twisted tapes with tree characteristic ratios of helix element length to the tape diameter (aspect ratio were studied. It was shown that twisted tapes with different aspect ratios reduce fouling of membrane by a factor of three or more. The presence of twisted tape induces changes in the flow patterns from straight to helicoidally thus producing turbulence flow at the lower cross-flow rates. Turbulence intensification prevents accumulation of proteins at membrane surface enabling reduction in reversible fouling what results in the reduction of overall membrane fouling. The best performance was achieved using a twisted tape with the lowest aspect ratio of 1.0. This promoter reduces fouling seven times at low transmembrane pressure and low cross-flow velocity. The twisted tape with aspect ratio 1.0 induces the most intensive turbulence, the longest helicoidal flow path, and appearance of vortices near the membrane surfaces

  11. Investigation of Structural Behavior due to Bend-Twist Couplings in Wind Turbine Blades

    DEFF Research Database (Denmark)

    Fedorov, Vladimir; Dimitrov, Nikolay Krasimirov; Berggreen, Christian

    2010-01-01

    for predicting the torsional response of the wind turbine blades with built-in bend-twist couplings. Additionally, a number of improved full-scale tests using an advanced bi-axial servo-hydraulic load control have been performed on a wind turbine blade section provided by Vestas Wind Systems A/S. In the present......One of the problematic issues concerning the design of future large composite wind turbine blades is the prediction of bend-twist couplings and torsion behaviour. The current work is a continuation of a previous work [1,2], and it examines different finite element modelling approaches...... of the blade cross section as the defining surface, off-setting the location of the shell elements according to the specified thickness. The experimental full-scale tests were carried out on an 8 m section of a 23 m wind turbine blade with specially implemented bend-twist coupling. The blade was tested under...

  12. Mechanical behaviors of multi-filament twist superconducting strand under tensile and cyclic loading

    Science.gov (United States)

    Wang, Xu; Li, Yingxu; Gao, Yuanwen

    2016-01-01

    The superconducting strand, serving as the basic unit cell of the cable-in-conduit-conductors (CICCs), is a typical multi-filament twist composite which is always subjected to a cyclic loading under the operating condition. Meanwhile, the superconducting material Nb3Sn in the strand is sensitive to strain frequently relating to the performance degradation of the superconductivity. Therefore, a comprehensive study on the mechanical behavior of the strand helps understanding the superconducting performance of the strained Nb3Sn strands. To address this issue, taking the LMI (internal tin) strand as an example, a three-dimensional structural finite element model, named as the Multi-filament twist model, of the strand with the real configuration of the LMI strand is built to study the influences of the plasticity of the component materials, the twist of the filament bundle, the initial thermal residual stress and the breakage and its evolution of the filaments on the mechanical behaviors of the strand. The effective properties of superconducting filament bundle with random filament breakage and its evolution versus strain are obtained based on the damage theory of fiber-reinforced composite materials proposed by Curtin and Zhou. From the calculation results of this model, we find that the occurrence of the hysteresis loop in the cyclic loading curve is determined by the reverse yielding of the elastic-plastic materials in the strand. Both the initial thermal residual stress in the strand and the pitch length of the filaments have significant impacts on the axial and hysteretic behaviors of the strand. The damage of the filaments also affects the axial mechanical behavior of the strand remarkably at large axial strain. The critical current of the strand is calculated by the scaling law with the results of the Multi-filament twist model. The predicted results of the Multi-filament twist model show an acceptable agreement with the experiment.

  13. Substrate analysis of the Pneumocystis carinii protein kinases PcCbk1 and PcSte20 using yeast proteome microarrays provides a novel method for Pneumocystis signalling biology.

    Science.gov (United States)

    Kottom, Theodore J; Limper, Andrew H

    2011-10-01

    Pneumocystis carinii (Pc) undergoes morphological transitions between cysts and trophic forms. We have previously described two Pc serine/threonine kinases, termed PcCbk1 and PcSte20, with PcSte20 belonging to a family of kinases involved in yeast mating, while PcCbk1 is a member of a group of protein kinases involved in regulation of cell cycle, shape, and proliferation. As Pc remains genetically intractable, knowledge on specific substrates phosphorylated by these kinases remains limited. Utilizing the phylogenetic relatedness of Pc to Saccharomyces cerevisiae, we interrogated a yeast proteome microarray containing >4000 purified protein based peptides, leading to the identification of 18 potential PcCbk1 and 15 PcSte20 substrates (Z-score > 3.0). A number of these potential protein substrates are involved in bud site selection, polarized growth, and response to mating α factor and pseudohyphal and invasive growth. Full-length open reading frames suggested by the PcCbk1 and PcSte20 protoarrays were amplified and expressed. These five proteins were used as substrates for PcCbk1 or PcSte20, with each being highly phosphorylated by the respective kinase. Finally, to demonstrate the utility of this method to identify novel PcCbk1 and PcSte20 substrates, we analysed DNA sequence data from the partially complete Pc genome database and detected partial sequence information of potential PcCbk1 kinase substrates PcPxl1 and PcInt1. We additionally identified the potential PcSte20 kinase substrate PcBdf2. Full-length Pc substrates were cloned and expressed in yeast, and shown to be phosphorylated by the respective Pc kinases. In conclusion, the yeast protein microarray represents a novel crossover technique for identifying unique potential Pc kinase substrates. Copyright © 2011 John Wiley & Sons, Ltd.

  14. Polyhedral-Like NiMn-Layered Double Hydroxide/Porous Carbon as Electrode for Enhanced Electrochemical Performance Supercapacitors.

    Science.gov (United States)

    Yu, Mei; Liu, Ruili; Liu, Jianhua; Li, Songmei; Ma, Yuxiao

    2017-11-01

    Polyhedral-like NiMn-layered double hydroxide/porous carbon (NiMn-LDH/PC-x) composites are successfully synthesized by hydrothermal method (x = 1, 2 means different mass percent of porous carbon (PC) in composites). The NiMn-LDH/PC-1 composites possess specific capacitance 1634 F g -1 at a current density of 1 A g -1 , and it is much better than that of pure LDH (1095 F g -1 at 1 A g -1 ). Besides, the sample can retain 84.58% of original capacitance after 3000 cycles at 15 A g -1 . An asymmetric supercapacitor with NiMn-LDH/PC-1 as anode and activated carbon as cathode is fabricated, and the supercapacitor can achieve an energy density of 18.60 Wh kg -1 at a power density of 225.03 W kg -1 . The enhanced electrochemical performance attributes to the high faradaic pseudocapacitance of NiMn-LDH, the introduction of PC, and the 3D porous structure of LDH/PC-1 composites. The introduction of PC hinders serious agglomeration of LDH and further accelerates ions transport. The encouraging results indicate that these materials are one of the most potential candidates for energy storage devices. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. The comparison of CAP88-PC version 2.0 versus CAP88-PC version 1.0

    International Nuclear Information System (INIS)

    Yakubovich, B.A.; Klee, K.O.; Palmer, C.R.; Spotts, P.B.

    1997-12-01

    40 CFR Part 61 (Subpart H of the NESHAP) requires DOE facilities to use approved sampling procedures, computer models, or other approved procedures when calculating Effective Dose Equivalent (EDE) values to members of the public. Currently version 1.0 of the approved computer model CAP88-PC is used to calculate EDE values. The DOE has upgraded the CAP88-PC software to version 2.0. This version provides simplified data entry, better printing characteristics, the use of a mouse, and other features. The DOE has developed and released version 2.0 for testing and comment. This new software is a WINDOWS based application that offers a new graphical user interface with new utilities for preparing and managing population and weather data, and several new decay chains. The program also allows the user to view results before printing. This document describes a test that confirmed CAP88-PC version 2.0 generates results comparable to the original version of the CAP88-PC program

  16. First tests of twisted-pair HTS 1 kA range cables for use in superconducting links

    CERN Document Server

    Ballarino, A; Hurte, J; Sitko, M; Willering, G

    2011-01-01

    The requirement at CERN for 1 kA range High Temperature Superconducting (HTS) cables optimized for long electrical transfer has led to the design and assembly of a novel type of cable that can be made from pre-reacted MgB2, Bi-2223 or YBCO tapes. The cable consists of an assembly of twisted pairs, each of which is made from three superconducting tapes with the required copper stabilizer. The twisted pair cable is designed to transfer a DC current of ± 600 A in helium gas environment. The paper reports on the results of the electrical tests performed on twisted-pair cables of identical structure and made from commercially available MgB2, Bi-2223 and YBCO tapes. The twist pitch of the cables is adapted to match the mechanical properties of the different superconductors. Critical current tests were performed at both liquid helium and liquid nitrogen temperature. The electrical performance of several cables made from different conductors is reported and compared.

  17. Adaptive twisting sliding mode algorithm for hypersonic reentry vehicle attitude control based on finite-time observer.

    Science.gov (United States)

    Guo, Zongyi; Chang, Jing; Guo, Jianguo; Zhou, Jun

    2018-06-01

    This paper focuses on the adaptive twisting sliding mode control for the Hypersonic Reentry Vehicles (HRVs) attitude tracking issue. The HRV attitude tracking model is transformed into the error dynamics in matched structure, whereas an unmeasurable state is redefined by lumping the existing unmatched disturbance with the angular rate. Hence, an adaptive finite-time observer is used to estimate the unknown state. Then, an adaptive twisting algorithm is proposed for systems subject to disturbances with unknown bounds. The stability of the proposed observer-based adaptive twisting approach is guaranteed, and the case of noisy measurement is analyzed. Also, the developed control law avoids the aggressive chattering phenomenon of the existing adaptive twisting approaches because the adaptive gains decrease close to the disturbance once the trajectories reach the sliding surface. Finally, numerical simulations on the attitude control of the HRV are conducted to verify the effectiveness and benefit of the proposed approach. Copyright © 2018 ISA. Published by Elsevier Ltd. All rights reserved.

  18. Deformed quantum double realization of the toric code and beyond

    Science.gov (United States)

    Padmanabhan, Pramod; Ibieta-Jimenez, Juan Pablo; Bernabe Ferreira, Miguel Jorge; Teotonio-Sobrinho, Paulo

    2016-09-01

    Quantum double models, such as the toric code, can be constructed from transfer matrices of lattice gauge theories with discrete gauge groups and parametrized by the center of the gauge group algebra and its dual. For general choices of these parameters the transfer matrix contains operators acting on links which can also be thought of as perturbations to the quantum double model driving it out of its topological phase and destroying the exact solvability of the quantum double model. We modify these transfer matrices with perturbations and extract exactly solvable models which remain in a quantum phase, thus nullifying the effect of the perturbation. The algebra of the modified vertex and plaquette operators now obey a deformed version of the quantum double algebra. The Abelian cases are shown to be in the quantum double phase whereas the non-Abelian phases are shown to be in a modified phase of the corresponding quantum double phase. These are illustrated with the groups Zn and S3. The quantum phases are determined by studying the excitations of these systems namely their fusion rules and the statistics. We then go further to construct a transfer matrix which contains the other Z2 phase namely the double semion phase. More generally for other discrete groups these transfer matrices contain the twisted quantum double models. These transfer matrices can be thought of as being obtained by introducing extra parameters into the transfer matrix of lattice gauge theories. These parameters are central elements belonging to the tensor products of the algebra and its dual and are associated to vertices and volumes of the three dimensional lattice. As in the case of the lattice gauge theories we construct the operators creating the excitations in this case and study their braiding and fusion properties.

  19. Casimir energy for twisted piecewise uniform bosonic strings

    International Nuclear Information System (INIS)

    Lu, J.; Huang, B.; Shanghai, Teachers Univ.

    1998-01-01

    The Casimir energy for the transverse oscillations of piecewise uniform bosonic strings with either untwisted or twisted continuous conditions is discussed. After calculating the analytic values of zeros of the dispersion function under certain conditions, is obtained the Casimir energy for both open and closed bosonic strings composed of two or three segments

  20. Device for measuring well twistings

    Energy Technology Data Exchange (ETDEWEB)

    Kostin, Yu S; Golubin, S V; Keller, V F; Merzheyevskiy, A B; Zdorov, V P

    1982-01-01

    The device for measuring the well twistings with the use of fluids (poured into a vessel and which leave an imprint on the walls), containing a housing and adapter, is distinguished by the fact that in order to improve the accuracy of measurement by obtaining a clear imprint, it is equipped with cylinder that is spring-loaded in relation to the adapter, forming a vessel for fluid with the adapter. The adapter is made of two parts, one of which is made of neutral metal in relation to the fluid, and the other, from active in relation to the same fluid.

  1. Twist expansion of the nucleon structure functions, F{sub 2} and F{sub L}, in the DGLAP improved saturation model

    Energy Technology Data Exchange (ETDEWEB)

    Bartels, Jochen [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Golec-Biernat, Krzysztof [Rzeszow Univ. (Poland). Inst. of Physics; Polish Academy of Sciences, Krakow (Poland). Inst. of Nuclear Physics; Motkyka, Leszek [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Uniwersytet Jagiellonski, Krakow (Poland). Inst. Fizyki

    2009-11-15

    Higher twist effects in the deeply inelastic scattering are studied. We start with a short review of the theoretical results on higher twists in QCD. Within the saturation model we perform a twist analysis of the nucleon structure functions F{sub T} and F{sub L} at small value of the Bjorken variable x. The parameters of the model are fitted to the HERA F{sub 2} data, and we derive a prediction for the longitudinal structure function F{sub L}. We conclude that for F{sub L} the higher twist corrections are sizable whereas for F{sub 2}=F{sub T}+F{sub L} there is a nearly complete cancellation of twist-4 corrections in F{sub T} and F{sub L}. We discuss a few consequences for future LHC measurements. (orig.)

  2. Some exact computations on the twisted butterfly state in string field theory

    International Nuclear Information System (INIS)

    Okawa, Yuji

    2004-01-01

    The twisted butterfly state solves the equation of motion of vacuum string field theory in the singular limit. The finiteness of the energy density of the solution is an important issue, but possible conformal anomaly resulting from the twisting has prevented us from addressing this problem. We present a description of the twisted regulated butterfly state in terms of a conformal field theory with a vanishing central charge which consists of the ordinary bc ghosts and a matter system with c=26. Various quantities relevant to vacuum string field theory are computed exactly using this description. We find that the energy density of the solution can be finite in the limit, but the finiteness depends on the sub leading structure of vacuum string field theory. We further argue, contrary to our previous expectation, that contributions from sub leading terms in the kinetic term to the energy density can be of the same order as the contribution from the leading term which consists of the midpoint ghost insertion. (author)

  3. Corn silk maysin induces apoptotic cell death in PC-3 prostate cancer cells via mitochondria-dependent pathway.

    Science.gov (United States)

    Lee, Jisun; Lee, Seul; Kim, Sun-Lim; Choi, Ji Won; Seo, Jeong Yeon; Choi, Doo Jin; Park, Yong Il

    2014-12-05

    Despite recent advances in prostate cancer diagnostics and therapeutics, the overall survival rate still remains low. This study was aimed to assess potential anti-cancer activity of maysin, a major flavonoid of corn silk (CS, Zea mays L.), in androgen-independent human prostate cancer cells (PC-3). Maysin was isolated from CS of Kwangpyeongok, a Korean hybrid corn, via methanol extraction and preparative C18 reverse phase column chromatography. Maysin cytotoxicity was determined by either monitoring cell viability in various cancer cell lines by MTT assay or morphological changes. Apoptotic cell death was assessed by annexin V-FITC/PI double staining, depolarization of mitochondrial membrane potential (MMP), expression levels of Bcl-2 and pro-caspase-3 and by terminal transferase mediated dUTP-fluorescein nick end labeling (TUNEL) staining. Underlying mechanism in maysin-induced apoptosis of PC-3 cells was explored by evaluating its effects on Akt and ERK pathway. Maysin dose-dependently reduced the PC-3 cell viability, with an 87% reduction at 200 μg/ml. Maysin treatment significantly induced apoptotic cell death, DNA fragmentation, depolarization of MMP, and reduction in Bcl-2 and pro-caspase-3 expression levels. Maysin also significantly attenuated phosphorylation of Akt and ERK. A combined treatment with maysin and other known anti-cancer agents, including 5-FU, etoposide, cisplatin, or camptothecin, synergistically enhanced PC-3 cell death. These results suggested for the first time that maysin inhibits the PC-3 cancer cell growth via stimulation of mitochondria-dependent apoptotic cell death and may have a strong therapeutic potential for the treatment of either chemo-resistant or androgen-independent human prostate cancer. Copyright © 2014 Elsevier Inc. All rights reserved.

  4. Feature of extradosed PC bridge and its design; Daihenshin keburu PC kyo no tokucho to sono sekkei

    Energy Technology Data Exchange (ETDEWEB)

    Komiya, M. [Japan Bridge and Structure Institute Inc., Tokyo (Japan)

    1997-03-31

    A PC bridge with the eccentricity of the external cable increased by protruding the deviated member to the outside of the beam for more effective use of the external cable is called a `PC bridge with tendons of large eccentricity.` The extradosed bridge of main beam/cable joint type is a PC bridge with the external cable arranged via a tower-shaped eccentric member provided at the intermediate support, and resembles morphologically a cable stayed bridge having a very low tower. There are two types of extradosed bridges, i.e. a type with concrete coated external cable (cable stayed slab bridge) and the other with non-coated external cable (external cable stayed bridge). Features, structural planning and designing of the general external cable stayed bridge are shown. The features are the possession of intermediate characteristics of those of the PC beam bridge and the PC cable stayed bridge from the viewpoints of structural property, workability, economic efficiency, and scenic property. Outline of the plan, selection of structural data, design of the external cable, and structural characteristics in the ultimate state are discussed. 19 refs., 18 figs., 15 tabs.

  5. Measurement of velocity field in pipe with classic twisted tape using matching refractive index technique

    Energy Technology Data Exchange (ETDEWEB)

    Song, Min Seop; Park, So Hyun; Kim, Eung Soo [Seoul National Univ., Seoul (Korea, Republic of)

    2014-10-15

    Many researchers conducted experiments and numerical simulations to measure or predict a Nusselt number or a friction factor in a pipe with a twisted tape while some other studies focused on the heat transfer performance enhancement using various twisted tape configurations. However, since the optical access to the inner space of a pipe with a twisted tape was limited, the detailed flow field data were not obtainable so far. Thus, researchers mainly relied on the numerical simulations to obtain the data of the flow field. In this study, a 3D printing technique was used to manufacture a transparent test section for optical access. And also, a noble refractive index matching technique was used to eliminate optical distortion. This two combined techniques enabled to measure the velocity profile with Particle Image Velocimetry (PIV). The measured velocity field data can be used either to understand the fundamental flow characteristics around a twisted tape or to validate turbulence models in Computational Fluid Dynamics (CFD). In this study, the flow field in the test-section was measured for various flow conditions and it was finally compared with numerically calculated data. Velocity fields in a pipe with a classic twisted tape was measured using a particle image velocimetry (PIV) system. To obtain undistorted particle images, a noble optical technique, refractive index matching, was used and it was proved that high-quality image can be obtained from this experimental equipment. The velocity data from the PIV was compared with the CFD simulations.

  6. Measurement of velocity field in pipe with classic twisted tape using matching refractive index technique

    International Nuclear Information System (INIS)

    Song, Min Seop; Park, So Hyun; Kim, Eung Soo

    2014-01-01

    Many researchers conducted experiments and numerical simulations to measure or predict a Nusselt number or a friction factor in a pipe with a twisted tape while some other studies focused on the heat transfer performance enhancement using various twisted tape configurations. However, since the optical access to the inner space of a pipe with a twisted tape was limited, the detailed flow field data were not obtainable so far. Thus, researchers mainly relied on the numerical simulations to obtain the data of the flow field. In this study, a 3D printing technique was used to manufacture a transparent test section for optical access. And also, a noble refractive index matching technique was used to eliminate optical distortion. This two combined techniques enabled to measure the velocity profile with Particle Image Velocimetry (PIV). The measured velocity field data can be used either to understand the fundamental flow characteristics around a twisted tape or to validate turbulence models in Computational Fluid Dynamics (CFD). In this study, the flow field in the test-section was measured for various flow conditions and it was finally compared with numerically calculated data. Velocity fields in a pipe with a classic twisted tape was measured using a particle image velocimetry (PIV) system. To obtain undistorted particle images, a noble optical technique, refractive index matching, was used and it was proved that high-quality image can be obtained from this experimental equipment. The velocity data from the PIV was compared with the CFD simulations

  7. Determinant of twisted chiral Dirac operator on the lattice

    International Nuclear Information System (INIS)

    Fosco, C.D.; Randjbar Daemi, S.

    1995-04-01

    Using the overlap formulation, we calculate the fermionic determinant on the lattice for chiral fermions with twisted boundary conditions in two dimensions. When the lattice spacing tends to zero we recover the results on the usual string-theory continuum calculations. (author). 13 refs

  8. Modification of the twist angle in chiral nematic polymer films by photoisomerization of the chiral dopant

    NARCIS (Netherlands)

    Witte, van de P.; Neuteboom, E.E.; Brehmer, M.; Lub, Johan

    1999-01-01

    A method for the production of polarization sensitive recordings in liquid crystalline polymers is presented. The system is based on local modification of the twist angle of chiral nematic polymer films. The twist angle of the polymer film is varied by modifying the chemical structure of the chiral

  9. Up-regulation of hypoxia inducible factor-1α by cobalt chloride correlates with proliferation and apoptosis in PC-2 cells

    Directory of Open Access Journals (Sweden)

    Dai Zhi-Jun

    2012-03-01

    Full Text Available Abstract Background The exact mechanism of the effects of hypoxia on the proliferation and apoptosis in carcinoma cells is still conflicting. This study investigated the variation of hypoxia-inducible factor-1α(HIF-1α expression and the apoptosis effect of hypoxia stimulated by cobalt chloride (CoCl2 in pancreatic cancer PC-2 cells. Methods PC-2 cells were cultured with different concentration (50-200 μmol/L of CoCl2 after 24-120 hours to simulate hypoxia in vitro. The proliferation of PC-2 cells was examined by MTT assay. The cellular morphology of PC-2 cells were observed by light inverted microscope and transmission electron microscope(EM. The expression of HIF-1α on mRNA and protein level was measured by semi-quantitive RT-PCR and Western blot analysis. Apoptosis of PC-2 cells were demonstrated by flow cytometry with Annexin V-FITC/PI double staining. Results MTT assay showed that the proliferation of PC-2 cells were stimulated in the first 72 h, while after treated over 72 h, a dose- dependent inhibition of cell growth could be observed. By using transmission electron microscope, swollen chondrosomes, accumulated chromatin under the nuclear membrane and apoptosis bodies were observed. Flow cytometer(FCM analysis showed the apoptosis rate was correlated with the dosage of CoCl2. RT-PCR and Western blot analysis indicated that hypoxia could up-regulate the expression of HIF-1α on both mRNA and protein levels. Conclusion Hypoxic microenvironment stimulated by CoCl2 could effectively induce apoptosis and influence cell proliferation in PC-2 cells, the mechanism could be related to up-expression of HIF-1α.

  10. Building the perfect PC

    CERN Document Server

    Thompson, Robert Bruce

    2006-01-01

    This popular Build-It-Yourself (BIY) PC book covers everything you want to know about building your own system: Planning and picking out the right components, step-by-step instructions for assembling your perfect PC, and an insightful discussion of why you'd want to do it in the first place. Most big brand computers from HP, Dell and others use lower-quality components so they can meet their aggressive pricing targets. But component manufacturers also make high-quality parts that you can either purchase directly, or obtain through distributors and resellers. Consumers and corporations

  11. Quench Property of Twisted-Pair MgB$_2$ Superconducting Cables in Helium Gas

    CERN Document Server

    Spurrell, J; Falorio, I; Pelegrin, J; Ballarino, A; Yang, Y

    2015-01-01

    CERN's twisted-pair superconducting cable is a novel design which offers filament transposition, low cable inductance and is particularly suited for tape conductors such as 2G YBCO coated conductors, Ag-sheathed Bi2223 tapes and Ni/Monel-sheathed MgB2 tapes. A typical design of such twistedpair cables consists of multiple superconducting tapes intercalated with thin copper tapes as additional stabilizers. The copper tapes are typically not soldered to the superconducting tapes so that sufficient flexibility is retained for the twisting of the tape assembly. The electrical and thermal contacts between the copper and superconducting tapes are an important parameter for current sharing, cryogenic stability and quench propagation. Using an MgB2 twisted-pair cable assembly manufactured at CERN, we have carried out minimum quench energy (MQE) and propagation velocity (vp) measurements with point-like heat deposition localized within a tape. Furthermore, different contacts between the copper and superconductor aroun...

  12. Denjoy minimal sets and Birkhoff periodic orbits for non-exact monotone twist maps

    Science.gov (United States)

    Qin, Wen-Xin; Wang, Ya-Nan

    2018-06-01

    A non-exact monotone twist map φbarF is a composition of an exact monotone twist map φ bar with a generating function H and a vertical translation VF with VF ((x , y)) = (x , y - F). We show in this paper that for each ω ∈ R, there exists a critical value Fd (ω) ≥ 0 depending on H and ω such that for 0 ≤ F ≤Fd (ω), the non-exact twist map φbarF has an invariant Denjoy minimal set with irrational rotation number ω lying on a Lipschitz graph, or Birkhoff (p , q)-periodic orbits for rational ω = p / q. Like the Aubry-Mather theory, we also construct heteroclinic orbits connecting Birkhoff periodic orbits, and show that quasi-periodic orbits in these Denjoy minimal sets can be approximated by periodic orbits. In particular, we demonstrate that at the critical value F =Fd (ω), the Denjoy minimal set is not uniformly hyperbolic and can be approximated by smooth curves.

  13. Low-Frequency Interlayer Raman Modes to Probe Interface of Twisted Bilayer MoS2.

    Science.gov (United States)

    Huang, Shengxi; Liang, Liangbo; Ling, Xi; Puretzky, Alexander A; Geohegan, David B; Sumpter, Bobby G; Kong, Jing; Meunier, Vincent; Dresselhaus, Mildred S

    2016-02-10

    van der Waals homo- and heterostructures assembled by stamping monolayers together present optoelectronic properties suitable for diverse applications. Understanding the details of the interlayer stacking and resulting coupling is crucial for tuning these properties. We investigated the low-frequency interlayer shear and breathing Raman modes (frequency and intensity changes of low-frequency modes. The frequency variation can be up to 8 cm(-1) and the intensity can vary by a factor of ∼5 for twisting angles near 0° and 60°, where the stacking is a mixture of high-symmetry stacking patterns and is thus sensitive to twisting. For twisting angles between 20° and 40°, the interlayer coupling is nearly constant because the stacking results in mismatched lattices over the entire sample. It follows that the Raman signature is relatively uniform. Note that for some samples, multiple breathing mode peaks appear, indicating nonuniform coupling across the interface. In contrast to the low-frequency interlayer modes, high-frequency intralayer Raman modes are much less sensitive to interlayer stacking and coupling. This research demonstrates the effectiveness of low-frequency Raman modes for probing the interfacial coupling and environment of twisted bilayer MoS2 and potentially other two-dimensional materials and heterostructures.

  14. Angular momentum transport with twisted exciton wave packets

    Science.gov (United States)

    Zang, Xiaoning; Lusk, Mark T.

    2017-10-01

    A chain of cofacial molecules with CN or CN h symmetry supports excitonic states with a screwlike structure. These can be quantified with the combination of an axial wave number and an azimuthal winding number. Combinations of these states can be used to construct excitonic wave packets that spiral down the chain with well-determined linear and angular momenta. These twisted exciton wave packets can be created and annihilated using laser pulses, and their angular momentum can be optically modified during transit. This allows for the creation of optoexcitonic circuits in which information, encoded in the angular momentum of light, is converted into excitonic wave packets that can be manipulated, transported, and then reemitted. A tight-binding paradigm is used to demonstrate the key ideas. The approach is then extended to quantify the evolution of twisted exciton wave packets in a many-body, multilevel time-domain density functional theory setting. In both settings, numerical methods are developed that allow the site-to-site transfer of angular momentum to be quantified.

  15. Multiperipheral ring dynamics and a definition of the complete twisted Reggeon loop

    International Nuclear Information System (INIS)

    Lucht, P.H.

    1977-11-01

    The t less than 0 multiperipheral formalism of Ciafaloni, DeTar, Misheloff, Mueller, Muzinich and Yesian is reviewed, extended, and applied to the ordered S-matrix whose ring amplitudes comprise the zeroth level of the topological expansion. Toller M-function notation is used throughout. The bootstrap and cylinder problems are formulated in terms of a well defined helicity pole propagator; a definition of the complete twisted Reggeon loop, which appears in the one-twist term of the cylinder, is given as a helicity pole expansion. Some consideration is given to the following subjects: diagonalization, naturality, threshold behavior, Regge cuts, and complex helicity

  16. Naked eye picometer resolution in a Michelson interferometer using conjugated twisted beams.

    Science.gov (United States)

    Emile, Olivier; Emile, Janine

    2017-01-15

    Michelson interferometry is one of the most widely used techniques for accuracy measurements. Its main characteristic feature is to infer a displacement in one of the arms of the interferometer from a phase measurement. Two different twisted beams, also called vortex beams, with opposite twisted rotations in each arm of the interferometer interfere in a daisy flower-like pattern. The number of petals is twice the topological charge. Their position depends on the relative phase of the beams. Naked eye detection of 44 pm displacements is achieved. The sensitivity of such an interferometer together with possible further improvements, and applications are then discussed.

  17. Pseudoscalar decay constants from Nf=2+1+1 twisted mass lattice QCD

    International Nuclear Information System (INIS)

    Farchioni, Federico; Petschlies, Marcus; Urbach, Carsten

    2010-12-01

    We present first results for the pseudoscalar decay constants f K , f D and f D S from lattice QCD with N f = 2 + 1 + 1 flavours of dynamical quarks. The lattice simulations have been performed by the European Twisted Mass collaboration (ETMC) using maximally twisted mass quarks. For the pseudoscalar decay constants we follow a mixed action approach by using so called Osterwalder-Seiler fermions in the valence sector for strange and charm quarks. The data for two values of the lattice spacing and several values of the up/down quark mass is analysed using chiral perturbation theory. (orig.)

  18. Critical Current Properties of HTS Twisted Stacked-Tape Cable in Subcooled- and Pressurized-Liquid Nitrogen

    International Nuclear Information System (INIS)

    Tomita, M; Suzuki, K; Fukumoto, Y; Ishihara, A; Akasaka, T; Kobayashi, Y; Maeda, A; Takayasu, M

    2015-01-01

    A 2 m length Twisted Stacked-Tape Cable (TSTC) conductor which was fabricated by 32-YBCO-tapes (4 mm width) with a 200 mm twist pitch was investigated at various temperatures near 77 K in subcooled- and pressurized-liquid nitrogen. The critical current of the TSTC cable which was 1.45 kA at 77 K measured from 64 K to 85 K by controlling the equilibrium vapor pressure of nitrogen bath and were varied from 3.65 kA at 64 K to 0.42 kA at 85 K. The temperature dependence of cables’ critical current agrees with that of the 4 mm width YBCO tape. These results are encouraging for applications of a compact Twisted Stacked-Tape Cable application in railway systems. (paper)

  19. THE EFFECT OF A TWISTED MAGNETIC FIELD ON THE PERIOD RATIO P{sub 1}/P{sub 2} OF NONAXISYMMETRIC MAGNETOHYDRODYNAMIC WAVES

    Energy Technology Data Exchange (ETDEWEB)

    Karami, K. [Department of Physics, University of Kurdistan, Pasdaran Street, Sanandaj (Iran, Islamic Republic of); Bahari, K., E-mail: KKarami@uok.ac.ir, E-mail: K.Bahari@razi.ac.ir [Physics Department, Faculty of Science, Razi University, Kermanshah (Iran, Islamic Republic of)

    2012-10-01

    We consider nonaxisymmetric magnetohydrodynamic (MHD) modes in a zero-beta cylindrical compressible thin magnetic flux tube modeled as a twisted core surrounded by a magnetically twisted annulus, with both embedded in a straight ambient external field. The dispersion relation is derived and solved analytically and numerically to obtain the frequencies of the nonaxisymmetric MHD waves. The main result is that the twisted magnetic annulus does affect the period ratio P{sub 1}/P{sub 2} of the kink modes. For the kink modes, the magnetic twist in the annulus region can achieve deviations from P{sub 1}/P{sub 2} = 2 of the same order of magnitude as in the observations. Furthermore, the effect of the internal twist on the fluting modes is investigated.

  20. Fermionic construction of vertex operators for twisted affine algebras

    International Nuclear Information System (INIS)

    Frappat, L.; Sorba, P.; Sciarrino, A.

    1988-03-01

    We construct vertex operator representations of the twisted affine algebras in terms of fermionic (or parafermionic in some cases) elementary fields. The folding method applied to the extended Dynkin diagrams of the affine algebras allows us to determine explicitly these fermionic fields as vertex operators

  1. Magnetic Helicity Estimations in Models and Observations of the Solar Magnetic Field. III. Twist Number Method

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Y. [School of Astronomy and Space Science and Key Laboratory of Modern Astronomy and Astrophysics in Ministry of Education, Nanjing University, Nanjing 210023 (China); Pariat, E.; Moraitis, K. [LESIA, Observatoire de Paris, PSL Research University, CNRS, Sorbonne Université, UPMC Univ. Paris 06, Univ. Paris Diderot, Sorbonne Paris Cité, F-92190 Meudon (France); Valori, G. [University College London, Mullard Space Science Laboratory, Holmbury St. Mary, Dorking, Surrey, RH5 6NT (United Kingdom); Anfinogentov, S. [Institute of Solar-Terrestrial Physics SB RAS 664033, Irkutsk, P.O. box 291, Lermontov Street, 126a (Russian Federation); Chen, F. [Max-Plank-Institut für Sonnensystemforschung, D-37077 Göttingen (Germany); Georgoulis, M. K. [Research Center for Astronomy and Applied Mathematics of the Academy of Athens, 4 Soranou Efesiou Street, 11527 Athens (Greece); Liu, Y. [W. W. Hansen Experimental Physics Laboratory, Stanford University, Stanford, CA 94305 (United States); Thalmann, J. K. [Institute of Physics, Univeristy of Graz, Universitätsplatz 5/II, A-8010 Graz (Austria); Yang, S., E-mail: guoyang@nju.edu.cn [Key Laboratory of Solar Activity, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 (China)

    2017-05-01

    We study the writhe, twist, and magnetic helicity of different magnetic flux ropes, based on models of the solar coronal magnetic field structure. These include an analytical force-free Titov–Démoulin equilibrium solution, non-force-free magnetohydrodynamic simulations, and nonlinear force-free magnetic field models. The geometrical boundary of the magnetic flux rope is determined by the quasi-separatrix layer and the bottom surface, and the axis curve of the flux rope is determined by its overall orientation. The twist is computed by the Berger–Prior formula, which is suitable for arbitrary geometry and both force-free and non-force-free models. The magnetic helicity is estimated by the twist multiplied by the square of the axial magnetic flux. We compare the obtained values with those derived by a finite volume helicity estimation method. We find that the magnetic helicity obtained with the twist method agrees with the helicity carried by the purely current-carrying part of the field within uncertainties for most test cases. It is also found that the current-carrying part of the model field is relatively significant at the very location of the magnetic flux rope. This qualitatively explains the agreement between the magnetic helicity computed by the twist method and the helicity contributed purely by the current-carrying magnetic field.

  2. Novel cell parameter determination of a twisted-nematic liquid crystal display

    International Nuclear Information System (INIS)

    Huang Xia; Jing Hai; Fu Guozhu

    2008-01-01

    In this paper a novel method is proposed to determine the cell parameters including the twist angle, optic retardation and rubbing direction of twisted-nematic liquid crystal displays (TNLCD) by rotating the TNLCD. It is a single-wavelength method. Because using subtraction equation of transmittance as curve fitting equation, the influence of the light from environment and the absorption by polarizer, the sample of TNLCD and analyser on the transmittance is eliminated. Accurate results can also be obtained in imperfect darkness. By large numbers of experiments, we found that not only the experimental setup is quite simple and can be easily adopted to be carried out, but also the results are accurate

  3. Experimental Analysis of the Thermo-Hydraulic Performance on a Cylindrical Parabolic Concentrating Solar Water Heater with Twisted Tape Inserts in an Absorber Tube

    Science.gov (United States)

    Kumar, Birendra; Nayak, Rajen Kumar; Singh, S. N.

    2018-05-01

    A twisted tape inserted in an absorber tube may be an excellent option to enhance the performance of a cylindrical parabolic concentrating solar collector (CPC). The present work is an experimental study of the flow and heat transfer with and without twisted tape inserts in the absorber tube of a CPC. Results are presented for mass flow rates of water, ṁ=0.0198-0.0525 kg/s, twist ratio, y=5-10 and Reynolds number, Re=2577.46-6785.55. In the present study, we found that the outlet water temperature, collector efficiency and Nusselt number (Nu) are higher in the twisted tapes as compared to those without the twisted tape inserts in the absorber tube of the CPC. For fixed mass flow rate of water ṁ, the To and η increased with the decrease in twist ratio, y, and is higher in lower twist ratio, y=5, of the twisted tapes. The whole experiment was performed at the Indian Institute of Technology (ISM) in Dhanbad, India during the months of March-April 2017. Based on the experimental data, the correlations for the Nu and friction factor were also developed.

  4. Enhancement of heat transfer using varying width twisted tape inserts

    African Journals Online (AJOL)

    International Journal of Engineering, Science and Technology ... experimental investigations of the augmentation of turbulent flow heat transfer in a horizontal tube by means of varying width twisted tape inserts with air as the working fluid.

  5. Experimental investigation of heat transfer and friction factor characteristics of thermosyphon solar water heater system fitted with spacer at the trailing edge of Left-Right twisted tapes

    International Nuclear Information System (INIS)

    Jaisankar, S.; Radhakrishnan, T.K.; Sheeba, K.N.; Suresh, S.

    2009-01-01

    Experimental investigation of heat transfer and friction factor characteristics of thermosyphon solar water heater with full length Left-Right twist, twist fitted with rod and spacer at the trailing edge for lengths of 100, 200 and 300 mm for twist ratio 3 and 5 has been studied. The experimental data for plain tube collector has been compared with fundamental equation within a discrepancy of ±7.41% and ±14.97% for Nusselt number and friction factor, respectively. Result shows that the Nusselt number decreases by 11% and 19% for twist fitted with rod and twist with spacer, respectively, when compared with full length twist. Friction factor also decreases by 18% and 29% for twist fitted with rod and spacer, respectively, as compared with full length twist. The heat enhancement in twist fitted with rod at the trailing edge is maximum when compared with twist fitted with spacer because the swirl flow is maintained throughout the length of rod.

  6. Organic photovoltaic effects depending on CuPc layer thickness

    International Nuclear Information System (INIS)

    Hur, Sung Woo; Kim, Tae Wan; Chung, Dong Hoe; Oh, Hyun Seok; Kim, Chung Hyeok; Lee, Joon Ung; Park, Jong Wook

    2004-01-01

    Organic photovoltaic effects were studied in device structures of ITO/CuPc/Al and ITO/CuPc/C 60 /BCP/Al by varying the CuPc layer thickness. Since the exciton diffusion length is relatively short in organic semiconductors, a study on the thickness-dependent photovoltaic effects is important. The thickness of the CuPc layer was varied from 10 nm to 50 nm. We found that the optimum CuPc layer thickness was around 40 nm from the analysis of the current density-voltage characteristics in an ITO/CuPc/Al photovoltaic cell. The efficiency of the device shows that the multi-layered heterojunction structure is more appropriate for photovoltaic cells.

  7. The clinical presentation and genotype of protein C deficiency with double mutations of the protein C gene.

    Science.gov (United States)

    Inoue, Hirofumi; Terachi, Shin-Ichi; Uchiumi, Takeshi; Sato, Tetsuji; Urata, Michiyo; Ishimura, Masataka; Koga, Yui; Hotta, Taeko; Hara, Toshiro; Kang, Dongchon; Ohga, Shouichi

    2017-07-01

    Severe protein C (PC) deficiency is a rare heritable thrombophilia leading to thromboembolic events during the neonatal period. It remains unclear how individuals with complete PC gene (PROC) defects develop or escape neonatal stroke or purpura fulminans (PF). We studied the onset of disease and the genotype of 22 PC-deficient patients with double mutations in PROC based on our cohort (n = 12) and the previous reports (n = 10) in Japan. Twenty-two patients in 20 unrelated families had 4 homozygous and 18 compound heterozygous mutations. Sixteen newborns presented with PF (n = 11, 69%), intracranial thromboembolism and hemorrhage (n = 13, 81%), or both (n = 8, 50%), with most showing a plasma PC activity of <10%. Six others first developed overt thromboembolism when they were over 15 years of age, showing a median PC activity of 31% (range: 19-52%). Fifteen of the 22 patients (68%) had the five major mutations (G423VfsX82, V339M, R211W, M406I, and F181V) or two others (E68K and K193del) that have been reported in Japan. Three of the six late-onset cases, but none of the 16 neonatal cases, had the K193del mutation, which has been reported to be the most common variant of Chinese thrombophilia. A novel mutation of A309V was determined in a family of two patients with late onset. The genotype of double-PROC mutants might show less diversity than heterozygous mutants in terms of the timing of the onset of thrombophilia (newborn onset or late onset). © 2017 Wiley Periodicals, Inc.

  8. Translational control of TWIST1 expression in MCF-10A cell lines recapitulating breast cancer progression

    DEFF Research Database (Denmark)

    Nairismägi, Maarja-Liisa; Vislovukh, Andrii; Meng, Q

    2012-01-01

    and EMT, we found TWIST1 to be upregulated during EMT and downregulated early in carcinogenesis. The TWIST1 3′UTR contains putative regulatory elements, including miRNA target sites and two cytoplasmic polyadenylation elements (CPE). We found that miR-580, CPEB1, and CPEB2 act as negative regulators...

  9. Self-plied and twist-stable carbon nanotube yarn artificial muscles driven by organic solvent adsorption.

    Science.gov (United States)

    Jin, Kaiyun; Zhang, Silan; Zhou, Susheng; Qiao, Jian; Song, Yanhui; Di, Jiangtao; Zhang, Dengsong; Li, Qingwen

    2018-05-03

    Artificial yarn/fiber muscles have recently attracted considerable interest for various applications. These muscles can provide large-stroke tensile and torsional actuations, resulting from inserted twists. However, tensional tethering of twisted muscles is generally needed to avoid muscle snarling and untwisting. In this paper a carbon nanotube (CNT) yarn muscle that is tethering-free and twist-stable is reported. The yarn muscle is prepared by allowing the self-plying of a coiled CNT yarn. When driven by acetone adsorption, this muscle shows decoupled actuations, which provide fast and reversible ∼13.3% contraction strain against a constant stress corresponding to ∼38 000 times the muscle weight but almost zero torsional strokes. The cycling test shows that the self-plied muscle has very good structural stability and actuation reversibility. Applied joule heating can help increase the desorption of acetone and increase the operation frequency of the self-plied muscle. Furthermore, by controlling the coupling between the joule heating and acetone adsorption/desorption, tensile actuations from negative to positive have been achieved. This twist-stable feature could considerably facilitate the practical applications of such muscle.

  10. Puerarin protects differentiated PC12 cells from H₂O₂-induced apoptosis through the PI3K/Akt signalling pathway.

    Science.gov (United States)

    Zhang, Qin; Huang, Wei-Dong; Lv, Xue-Ying; Yang, Yun-Mei

    2012-05-01

    Oxidative stress has been implicated as a major mechanism underlying the pathogenesis of neurodegenerative disorders. ROS (reactive oxygen species) can cause cell death via apoptosis. NGF (nerve growth factor) differentiated rat PC12 cells have been extensively used to study the differentiation and apoptosis of neurons. This study has investigated the protective effects of puerarin in H2O2-induced apoptosis of differentiated PC12 cells, and the possible molecular mechanisms involved. Differentiated PC12 cells were incubated with 700 μM H2O2 in the absence or presence of different doses of puerarin (4, 8 and 16 μM). Apoptosis was assessed by MTS [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium] assay, TUNEL (terminal deoxynucleotidyl transferase-mediated dUTP nick-end labelling) analysis and Annexin V-PI (propidium iodide) double staining flow cytometry. Protein levels of phospho-Akt and phospho-BAD (Bcl-2/Bcl-XL-antagonist, causing cell death) were assayed by Western blotting. After stimulation with H2O2 for 18 h, the viability of differentiated PC12 cells decreased significantly and a large number of cells underwent apoptosis. Differentiated PC12 cells were rescued from H2O2-induced apoptosis at different concentrations of puerarin in a dose-dependent manner. This was through increased production of phospho-Akt and phospho-BAD, an effect that could be reversed by wortmannin, an inhibitor of PI3K (phosphoinositide 3-kinase). The results suggest that puerarin may have neuroprotective effect through activation of the PI3K/Akt signalling pathway.

  11. Leo II PC

    Data.gov (United States)

    Kansas Data Access and Support Center — LEO II is a second-generation software system developed for use on the PC, which is designed to convert location references accurately between legal descriptions and...

  12. Spectral estimates for Dirichlet Laplacians on perturbed twisted tubes

    Czech Academy of Sciences Publication Activity Database

    Exner, Pavel; Barseghyan, Diana

    2014-01-01

    Roč. 8, č. 1 (2014), s. 167-183 ISSN 1846-3886 R&D Projects: GA ČR GAP203/11/0701 Institutional support: RVO:61389005 Keywords : Drichlet Laplacian * twisted tube * discrete spectrum * eigenvalue estimates Subject RIV: BE - Theoretical Physics Impact factor: 0.583, year: 2014

  13. Helicity conservation and twisted Seifert surfaces for superfluid vortices.

    Science.gov (United States)

    Salman, Hayder

    2017-04-01

    Starting from the continuum definition of helicity, we derive from first principles its different contributions for superfluid vortices. Our analysis shows that an internal twist contribution emerges naturally from the mathematical derivation. This reveals that the spanwise vector that is used to characterize the twist contribution must point in the direction of a surface of constant velocity potential. An immediate consequence of the Seifert framing is that the continuum definition of helicity for a superfluid is trivially zero at all times. It follows that the Gauss-linking number is a more appropriate definition of helicity for superfluids. Despite this, we explain how a quasi-classical limit can arise in a superfluid in which the continuum definition for helicity can be used. This provides a clear connection between a microscopic and a macroscopic description of a superfluid as provided by the Hall-Vinen-Bekarevich-Khalatnikov equations. This leads to consistency with the definition of helicity used for classical vortices.

  14. Supersymmetric partition functions and the three-dimensional A-twist

    Energy Technology Data Exchange (ETDEWEB)

    Closset, Cyril [Theory Department, CERN,CH-1211, Geneva 23 (Switzerland); Kim, Heeyeon [Perimeter Institute for Theoretical Physics,31 Caroline Street North, Waterloo, N2L 2Y5, Ontario (Canada); Willett, Brian [Kavli Institute for Theoretical Physics, University of California,Santa Barbara, CA 93106 (United States)

    2017-03-14

    We study three-dimensional N=2 supersymmetric gauge theories on M{sub g,p}, an oriented circle bundle of degree p over a closed Riemann surface, Σ{sub g}. We compute the M{sub g,p} supersymmetric partition function and correlation functions of supersymmetric loop operators. This uncovers interesting relations between observables on manifolds of different topologies. In particular, the familiar supersymmetric partition function on the round S{sup 3} can be understood as the expectation value of a so-called “fibering operator” on S{sup 2}×S{sup 1} with a topological twist. More generally, we show that the 3d N=2 supersymmetric partition functions (and supersymmetric Wilson loop correlation functions) on M{sub g,p} are fully determined by the two-dimensional A-twisted topological field theory obtained by compactifying the 3d theory on a circle. We give two complementary derivations of the result. We also discuss applications to F-maximization and to three-dimensional supersymmetric dualities.

  15. Stability of Medium-Bridged Twisted Amides in Aqueous Solutions

    Science.gov (United States)

    Szostak, Michal; Yao, Lei; Aubé, Jeffrey

    2012-01-01

    “Twisted” amides containing non-standard dihedral angles are typically hypersensitive to hydrolysis, a feature that has stringently limited their utility in water. We have synthesized a series of bridged lactams that contain a twisted amide linkage but which exhibit enhanced stability in aqueous environments. Many of these compounds were extracted unchanged from aqueous mixtures ranging from the strongly basic to the strongly acidic. NMR experiments showed that tricyclic lactams undergo reversible hydrolysis at extreme pH ranges, but that a number of compounds in this structure class are indefinitely stable under physiologically relevant pH conditions; one bicyclic example was additionally water-soluble. We examined the effect of structure on the reversibility of amide bond hydrolysis, which we attributed to the transannular nature of the amino acid analogs. These data suggest that medium-bridged lactams of these types should provide useful platforms for studying the behavior of twisted amides in aqueous systems. PMID:19178141

  16. Drag Performance of Twist Morphing MAV Wing

    Directory of Open Access Journals (Sweden)

    Ismail N.I.

    2016-01-01

    Full Text Available Morphing wing is one of latest evolution found on MAV wing. However, due to few design problems such as limited MAV wing size and complicated morphing mechanism, the understanding of its aerodynamic behaviour was not fully explored. In fact, the basic drag distribution induced by a morphing MAV wing is still remained unknown. Thus, present work is carried out to compare the drag performance between a twist morphing wing with membrane and rigid MAV wing design. A quasi-static aeroelastic analysis by using the Ansys-Fluid Structure Interaction (FSI method is utilized in current works to predict the drag performance a twist morphing MAV wing design. Based on the drag pattern study, the results exhibits that the morphing wing has a partial similarities in overall drag pattern with the baseline (membrane and rigid wing. However, based CD analysis, it shows that TM wing induced higher CD magnitude (between 25% to 82% higher than to the baseline wing. In fact, TM wing also induced the largest CD increment (about 20% to 27% among the wings. The visualization on vortex structure revealed that TM wing also produce larger tip vortex structure (compared to baseline wings which presume to promote higher induce drag component and subsequently induce its higher CD performance.

  17. Dataset of TWIST1-regulated genes in the cranial mesoderm and a transcriptome comparison of cranial mesoderm and cranial neural crest

    Directory of Open Access Journals (Sweden)

    Heidi Bildsoe

    2016-12-01

    Full Text Available This article contains data related to the research article entitled “Transcriptional targets of TWIST1 in the cranial mesoderm regulate cell-matrix interactions and mesenchyme maintenance” by Bildsoe et al. (2016 [1]. The data presented here are derived from: (1 a microarray-based comparison of sorted cranial mesoderm (CM and cranial neural crest (CNC cells from E9.5 mouse embryos; (2 comparisons of transcription profiles of head tissues from mouse embryos with a CM-specific loss-of-function of Twist1 and control mouse embryos collected at E8.5 and E9.5; (3 ChIP-seq using a TWIST1-specific monoclonal antibody with chromatin extracts from TWIST1-expressing MDCK cells, a model for a TWIST1-dependent mesenchymal state.

  18. Surface-type nonvolatile electric memory elements based on organic-on-organic CuPc-H2Pc heterojunction

    International Nuclear Information System (INIS)

    Karimov, Khasan S.; Muqeet Rehman, M.; Zameer Abbas, S.; Ahmad, Zubair; Touati, Farid; Mahroof-Tahir, M.

    2015-01-01

    A novel surface-type nonvolatile electric memory elements based on organic semiconductors CuPc and H 2 Pc are fabricated by vacuum deposition of the CuPc and H 2 Pc films on preliminary deposited metallic (Ag and Cu) electrodes. The gap between Ag and Cu electrodes is 30–40 μm. For the current–voltage (I–V) characteristics the memory effect, switching effect, and negative differential resistance regions are observed. The switching mechanism is attributed to the electric-field-induced charge transfer. As a result the device switches from a low to a high-conductivity state and then back to a low conductivity state if the opposite polarity voltage is applied. The ratio of resistance at the high resistance state to that at the low resistance state is equal to 120–150. Under the switching condition, the electric current increases ∼ 80–100 times. A comparison between the forward and reverse I–V characteristics shows the presence of rectifying behavior. (paper)

  19. Advanced Twisted Pair Cables for Distributed Local Area Networks in Intelligent Structure Systems

    Science.gov (United States)

    Semenov, Andrey

    2018-03-01

    The possibility of a significant increase in the length of cable communication channels of local area networks of automation and engineering support systems of buildings in the case of their implementation on balanced twisted pair cables is shown. Assuming a direct connection scheme and an effective speed of 100 Mbit/s, analytical relationships are obtained for the calculation of the maximum communication distance. The necessity of using in the linear part of such systems of twisted pair cables with U/UTP structure and interference parameters at the level of category 5e is grounded.

  20. Evidence for higher twist effects in fast π- production by antineutrinos in neon

    Science.gov (United States)

    Fitch, P. J.; Kasper, P.; Cooper-Sarkar, A. M.; Aderholz, M.; Armenise, N.; Azemoon, T.; Bertrand, D.; Berggren, M.; Bullock, F. W.; Calicchio, M.; Clayton, E. F.; Coghen, T.; Erriquez, O.; Gerbier, G.; Guy, J.; Hulth, P. O.; Iaselli, G.; Jones, G. T.; Lagraa, M.; Marage, P.; Middleton, R. P.; Miller, D.; Mobayyen, M. M.; Neveu, M.; O'Neale, S. W.; Parker, M. A.; Sansum, R. A.; Simopoulou, E.; Varvell, K.; Vallée, C.; Vayaki, A.; Venus, W.; Wachsmuth, H.; Wittek, W.; Wells, J.; Zevgolatakos, E.

    1986-03-01

    Evidence for a significant higher twist contribution to high z π- production in antineutrino scattering is presented. In events with W>3 GeV and Q 2>1 GeV2 in our data, it accounts for (51 ±8)% of all π- with z above 0.5. It is consistent with the z- Q 2 correlations of Berger's higher twist prediction. The data are inconclusive concerning the predicted y-z correlation and p T dependence. The z - Q 2 correlation is not adequately described by the Lund Monte-Carlo.

  1. Evidence for higher twist effects in fast π- production by antineutrinos in neon

    International Nuclear Information System (INIS)

    Fitch, P.J.; Azemoon, T.; Bullock, F.W.; Sansum, R.A.; Armenise, N.; Calicchio, M.; Erriquez, O.; Iaselli, G.; Bertrand, D.; Marage, P.; Berggren, M.; Hulth, P.O.; Coghen, T.; Gerbier, G.; Lagraa, M.; Neveu, M.; Parker, M.A.; Wachsmuth, H.; Simopoulo, E.; Vayaki, A.; Zevgolatakos, E.; Varvell, K.; Wells, J.; Vallee, C.

    1986-01-01

    Evidence for a significant higher twist contribution to high zπ - production in antineutrino scattering is presented. In events with W>3 GeV and Q 2 >1 GeV 2 in our data, it accounts for (51+-8)% of all π - with z above 0.5. It is consistent with the z-Q 2 correlations of Berger's higher twist prediction. The data are inconclusive concerning the predicted y-z correlation and psub(T) dependence. The z-Q 2 correlation is not adequately described by the Lund Monte-Carlo. (orig.)

  2. Nucleon scalar matrix elements with N{sub f}=2+1+1 twisted mass fermions

    Energy Technology Data Exchange (ETDEWEB)

    Dinter, Simon; Drach, Vincent; Jansen, Karl [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC

    2011-12-15

    We investigate scalar matrix elements of the nucleon using N{sub f}=2+1+1 flavors of maximally twisted mass fermions at a fixed value of the lattice spacing of a{approx}0.078 fm. We compute disconnected contributions to the relevant three-point functions using an efficient noise reduction technique. Using these methods together with an only multiplicative renormalization applicable for twisted mass fermions, allows us to obtain accurate results in the light and strange sector. (orig.)

  3. Further Examination of the Vibratory Loads Reduction Results from the NASA/ARMY/MIT Active Twist Rotor Test

    Science.gov (United States)

    Wilbur, Matthew L.; Yeager, William T., Jr.; Sekula, Martin K.

    2002-01-01

    The vibration reduction capabilities of a model rotor system utilizing controlled, strain-induced blade twisting are examined. The model rotor blades, which utilize piezoelectric active fiber composite actuators, were tested in the NASA Langley Transonic Dynamics Tunnel using open-loop control to determine the effect of active-twist on rotor vibratory loads. The results of this testing have been encouraging, and have demonstrated that active-twist rotor designs offer the potential for significant load reductions in future helicopter rotor systems. Active twist control was found to use less than 1% of the power necessary to operate the rotor system and had a pronounced effect on both rotating- and fixed-system loads, offering reductions in individual harmonic loads of up to 100%. A review of the vibration reduction results obtained is presented, which includes a limited set of comparisons with results generated using the second-generation version of the Comprehensive Analytical Model of Rotorcraft Aerodynamics and Dynamics (CAMRAD II) rotorcraft comprehensive analysis.

  4. Some new quasi-twisted ternary linear codes

    Directory of Open Access Journals (Sweden)

    Rumen Daskalov

    2015-09-01

    Full Text Available Let [n, k, d]_q code be a linear code of length n, dimension k and minimum Hamming distance d over GF(q. One of the basic and most important problems in coding theory is to construct codes with best possible minimum distances. In this paper seven quasi-twisted ternary linear codes are constructed. These codes are new and improve the best known lower bounds on the minimum distance in [6].

  5. New twists to QCD at large-N

    International Nuclear Information System (INIS)

    Klinkhamer, F.R.

    1984-01-01

    The recently discovered reduced models of Quantum Chromodynamics in the limit of a large number (N) of colors are discussed, in particular the version that employs appropriate Z(N) twists. Some preliminary numerical data are presented, together with some new analytic results (saddle-points). This may be of some help for understanding the mechanism of confinement, which presumably is the same for all N. Also, the reduced chiral model in two dimensions is discussed

  6. Raman Excitation Profile of the G-band Enhancement in Twisted Bilayer Graphene

    Science.gov (United States)

    Eliel, G. S. N.; Ribeiro, H. B.; Sato, K.; Saito, R.; Lu, Chun-Chieh; Chiu, Po-Wen; Fantini, C.; Righi, A.; Pimenta, M. A.

    2017-12-01

    A resonant Raman study of twisted bilayer graphene (TBG) samples with different twisting angles using many different laser lines in the visible range is presented. The samples were fabricated by CVD technique and transferred to Si/SiO2 substrates. The Raman excitation profiles of the huge enhancement of the G-band intensity for a group of different TBG flakes were obtained experimentally, and the analysis of the profiles using a theoretical expression for the Raman intensities allowed us to obtain the energies of the van Hove singularities generated by the Moiré patterns and the lifetimes of the excited state of the Raman process. Our results exhibit a good agreement between experimental and calculated energies for van Hove singularities and show that the lifetime of photoexcited carrier does not depend significantly on the twisting angle in the range intermediate angles ( 𝜃 between 10∘ and 15∘). We observed that the width of the resonance window (Γ ≈ 250 meV) is much larger than the REP of the Raman modes of carbon nanotubes, which are also enhanced by resonances with van Hove singularities.

  7. Heat bath method for the twisted Eguchi-Kawai model

    Energy Technology Data Exchange (ETDEWEB)

    Fabricius, K.; Haan, O.

    1984-08-16

    We reformulate the twisted Eguchi-Kawaii model in a way that allows us to use the heat bath method for the updating procedure of the link matrices. This new formulation is more efficient by a factor of 2.5 in computer time and of 2.3 in memory need.

  8. Craniosynostosis of coronal suture in Twist1+/- mice occurs through endochondral ossification recapitulating the physiological closure of posterior frontal suture

    Directory of Open Access Journals (Sweden)

    Bjorn eBehr

    2011-07-01

    Full Text Available Craniosynostosis, the premature closure of cranial suture, is a pathologic condition that affects 1/2000 live births. Saethre-Chotzen syndrome is a genetic condition characterized by craniosynostosis. The Saethre-Chotzen syndrome, which is defined by loss-of-function mutations in the TWIST gene, is the second most prevalent craniosynostosis. Although much of the genetics and phenotypes in craniosynostosis syndromes is understood, less is known about the underlying ossification mechanism during suture closure. We have previously demonstrated that physiological closure of the posterior frontal (PF suture occurs through endochondral ossification. Moreover, we revealed that antagonizing canonical Wnt signaling in the sagittal suture leads to endochondral ossification of the suture mesenchyme and sagittal synostosis, presumably by inhibiting Twist1. Classic Saethre-Chotzen syndrome is characterized by coronal synostosis, and the haploinsufficient Twist1+/- mice represents a suitable model for studying this syndrome. Thus, we seeked to understand the underlying ossification process in coronal craniosynostosis in Twist1+/- mice. Our data indicate that coronal suture closure in Twist1+/- mice occurs between postnatal day 9 to 13 by endochondral ossification, as shown by histology, gene expression analysis and immunohistochemistry. In conclusion, this study reveals that coronal craniosynostosis in Twist1+/- mice occurs through endochondral ossification. Moreover, it suggests that haploinsufficency of Twist1 gene, a target of canonical Wnt-signaling, and inhibitor of chondrogenesis, mimics conditions of inactive canonical Wnt-signaling leading to craniosynostosis.

  9. Optical twists in phase and amplitude

    DEFF Research Database (Denmark)

    Daria, Vincent R.; Palima, Darwin; Glückstad, Jesper

    2011-01-01

    where both phase and amplitude express a helical profile as the beam propagates in free space. Such a beam can be accurately referred to as an optical twister. We characterize optical twisters and demonstrate their capacity to induce spiral motion on particles trapped along the twisters’ path. Unlike LG...... beams, the far field projection of the twisted optical beam maintains a high photon concentration even at higher values of topological charge. Optical twisters have therefore profound applications to fundamental studies of light and atoms such as in quantum entanglement of the OAM, toroidal traps...

  10. NMSBA - Twist Resist - Rotational Exercise Module

    Energy Technology Data Exchange (ETDEWEB)

    Walker, Aaron [Twist Resist, Albuquerque, NM (United States); Reece, Blake D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Berger, Jason E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Guido, Steven Frank [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Linker, Taylor [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-08-01

    This report contains a summary of the work completed to develop a modular, rotational exercise device. In the report are images, diagrams, and explanations of the efforts contributed to the project since its inception. The purpose of this document is to provide a walk-through of the progress on this project, from the initial design concepts to the final design and work done, so that the customer (Twist Resist), or individuals/firms who work on this project in the future will have a springboard of ideas/concepts to work from.

  11. RNA-Based TWIST1 Inhibition via Dendrimer Complex to Reduce Breast Cancer Cell Metastasis

    Directory of Open Access Journals (Sweden)

    James Finlay

    2015-01-01

    Full Text Available Breast cancer is the leading cause of cancer-related deaths among women in the United States, and survival rates are lower for patients with metastases and/or triple-negative breast cancer (TNBC; ER, PR, and Her2 negative. Understanding the mechanisms of cancer metastasis is therefore crucial to identify new therapeutic targets and develop novel treatments to improve patient outcomes. A potential target is the TWIST1 transcription factor, which is often overexpressed in aggressive breast cancers and is a master regulator of cellular migration through epithelial-mesenchymal transition (EMT. Here, we demonstrate an siRNA-based TWIST1 silencing approach with delivery using a modified poly(amidoamine (PAMAM dendrimer. Our results demonstrate that SUM1315 TNBC cells efficiently take up PAMAM-siRNA complexes, leading to significant knockdown of TWIST1 and EMT-related target genes. Knockdown lasts up to one week after transfection and leads to a reduction in migration and invasion, as determined by wound healing and transwell assays. Furthermore, we demonstrate that PAMAM dendrimers can deliver siRNA to xenograft orthotopic tumors and siRNA remains in the tumor for at least four hours after treatment. These results suggest that further development of dendrimer-based delivery of siRNA for TWIST1 silencing may lead to a valuable adjunctive therapy for patients with TNBC.

  12. Twisted equivariant K-theory, groupoids and proper actions

    OpenAIRE

    Cantarero, Jose

    2009-01-01

    In this paper we define twisted equivariant K-theory for actions of Lie groupoids. For a Bredon-compatible Lie groupoid, this defines a periodic cohomology theory on the category of finite CW-complexes with equivariant stable projective bundles. A classification of these bundles is shown. We also obtain a completion theorem and apply these results to proper actions of groups.

  13. Electronic transitions and band offsets in C60:SubPc and C60:MgPc on MoO3 studied by modulated surface photovoltage spectroscopy

    International Nuclear Information System (INIS)

    Fengler, S.; Dittrich, Th.; Rusu, M.

    2015-01-01

    Electronic transitions at interfaces between MoO 3 layers and organic layers of C 60 , SubPc, MgPc, and nano-composite layers of SubPc:C 60 and MgPc:C 60 have been studied by modulated surface photovoltage (SPV) spectroscopy. For all systems, time dependent and modulated SPV signals pointed to dissociation of excitons at the MoO 3 /organic layer interfaces with a separation of holes towards MoO 3 . The highest occupied molecular orbital (HOMO)-lowest unoccupied molecular orbital (LUMO) gaps (E HL ) of C 60 , SubPc, and MgPc and the effective E HL of SubPc:C 60 and MgPc:C 60 were measured. The offsets between the LUMO (ΔE L ) or HOMO (ΔE H ) bands were obtained with high precision and amounted to 0.33 or 0.73 eV for SubPc:C 60 , respectively, and to −0.33 or 0.67 eV for MgPc:C 60 , respectively. Exponential tails below E HL and most pronounced sub-bandgap transitions were characterized and ascribed to disorder and transitions from HOMO bands to unoccupied defect states

  14. Localization of twisted N=(0,2) gauged linear sigma models in two dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Closset, Cyril [Simons Center for Geometry and Physics, State University of New York, Stony Brook, NY 11794 (United States); Gu, Wei [Department of Physics MC 0435, Virginia Tech, 850 West Campus Drive, Blacksburg, VA 24061 (United States); Jia, Bei [Theory Group, Physics Department, University of Texas, Austin, TX 78612 (United States); Sharpe, Eric [Department of Physics MC 0435, Virginia Tech, 850 West Campus Drive, Blacksburg, VA 24061 (United States)

    2016-03-14

    We study two-dimensional N=(0,2) supersymmetric gauged linear sigma models (GLSMs) using supersymmetric localization. We consider N=(0,2) theories with an R-symmetry, which can always be defined on curved space by a pseudo-topological twist while preserving one of the two supercharges of flat space. For GLSMs which are deformations of N=(2,2) GLSMs and retain a Coulomb branch, we consider the A/2-twist and compute the genus-zero correlation functions of certain pseudo-chiral operators, which generalize the simplest twisted chiral ring operators away from the N=(2,2) locus. These correlation functions can be written in terms of a certain residue operation on the Coulomb branch, generalizing the Jeffrey-Kirwan residue prescription relevant for the N=(2,2) locus. For abelian GLSMs, we reproduce existing results with new formulas that render the quantum sheaf cohomology relations and other properties manifest. For non-abelian GLSMs, our methods lead to new results. As an example, we briefly discuss the quantum sheaf cohomology of the Grassmannian manifold.

  15. Flavour symmetry restoration and kaon weak matrix elements in quenched twisted mass QCD

    CERN Document Server

    Dimopoulos, P; Palombi, Filippo; Peña, C; Sint, S; Vladikas, A

    2007-01-01

    We simulate two variants of quenched twisted mass QCD (tmQCD), with degenerate Wilson quarks of masses equal to or heavier than half the strange quark mass. We use Ward identities in order to measure the twist angles of the theory and thus check the quality of the tuning of mass parameters to a physics condition which stays constant as the lattice spacing is varied. Flavour symmetry breaking in tmQCD is studied in a framework of two fully twisted and two standard Wilson quark flavours, tuned to be degenerate in the continuum. Comparing pseudoscalar masses, obtained from connected quark diagrams made of tmQCD and/or standard Wilson quark propagators, we confirm that flavour symmetry breaking effects, which are at most 5%, decrease as we approach the continuum limit. We also compute the pseudoscalar decay constant in the continuum limit, with reduced systematics. As a consequence of improved tuning of the mass parameters at $\\beta = 6.1$, we reanalyse our previous $B_K$ results. Our main phenomenological findin...

  16. The quiver at the bottom of the twisted nilpotent cone on $\\mathbb P^1$

    OpenAIRE

    Rayan, Steven

    2016-01-01

    For the moduli space of Higgs bundles on a Riemann surface of positive genus, critical points of the natural Morse-Bott function lie along the nilpotent cone of the Hitchin fibration and are representations of $\\mbox{A}$-type quivers in a twisted category of holomorphic bundles. The critical points that globally minimize the function are representations of $\\mbox{A}_1$. For twisted Higgs bundles on the projective line, the quiver describing the bottom of the cone is more complicated. We deter...

  17. Bubble generation in a twisted and bent DNA-like model

    DEFF Research Database (Denmark)

    Larsen, Peter Ulrik Vingaard; Christiansen, Peter Leth; Bang, Ole

    2004-01-01

    The DNA molecule is modeled by a parabola embedded chain with long-range interactions between twisted base pair dipoles. A mechanism for bubble generation is presented and investigated in two different configurations. Using random normally distributed initial conditions to simulate thermal...

  18. The static-light meson spectrum from twisted mass lattice QCD

    International Nuclear Information System (INIS)

    Jansen, Karl; Michael, Chris; Shindler, Andrea; Wagner, Marc

    2008-10-01

    We compute the static-light meson spectrum with N f =2 flavours of sea quarks using Wilson twisted mass lattice QCD. We consider five different values for the light quark mass corresponding to 300 MeV PS s mesons. (orig.)

  19. Experience using EPICS on PC platforms

    International Nuclear Information System (INIS)

    Hill, J.O.; Kasemire, K.U.

    1997-03-01

    The Experimental Physics and Industrial Control System (EPICS) has been widely adopted in the accelerator community. Although EPICS is available on many platforms, the majority of implementations have used UNIX workstations as clients, and VME- or VXI-based processors for distributed input output controllers. Recently, a significant portion of EPICS has been ported to personal computer (PC) hardware platforms running Microsoft's operating systems, and also Wind River System's real time vxWorks operating system. This development should significantly reduce the cost of deploying EPICS systems, and the prospect of using EPICS together with the many high quality commercial components available for PC platforms is also encouraging. A hybrid system using both PC and traditional platforms is currently being implemented at LANL for LEDA, the low energy demonstration accelerator under construction as part of the Accelerator Production of Tritium (APT) project. To illustrate these developments the authors compare their recent experience deploying a PC-based EPICS system with experience deploying similar systems based on traditional (UNIX-hosted) EPICS hardware and software platforms

  20. Heat bath method for the twisted Eguchi-Kawai model

    International Nuclear Information System (INIS)

    Fabricius, K.; Haan, O.

    1984-01-01

    We reformulate the twisted Eguchi-Kawaii model in a way that allows us to use the heat bath method for the updating procedure of the link matrices. This new formulation is more efficient by a factor of 2.5 in computer time and of 2.3 in memory need. (orig.)