Sample records for twelve chapters include

  1. Chapter Twelve

    African Journals Online (AJOL)


    dissemination in Nigeria· Some local jingles from Radio Nigeria Purity F.M. .... Indigenous Language in Advertisement: Problems and Prospects – Thecla ... the rural newspapers from performing their role of rural development· The ..... Sharma Raman, M· and, S (2004), Technical Communication Principle and Practice· India:.

  2. Anglo-American Cataloging Rules. Chapter Twelve, Revised. Audiovisual Media and Special Instructional Materials. (United States)

    American Library Association, Chicago, IL.

    Chapter 12 of the Anglo-American Cataloging Rules has been revised to provide rules for works in the principal audiovisual media (motion pictures, filmstrips, videorecordings, slides, and transparencies) as well as instructional aids (charts, dioramas, flash cards, games, kits, microscope slides, models, and realia). The rules for main and added…

  3. Margalef revisited: A new phytoplankton mandala incorporating twelve dimensions, including nutritional physiology. (United States)

    Glibert, Patricia M


    Building on the classic depiction of the progression from a diatom to a dinoflagellate bloom as a function of nutrients and turbulence, known as the "Margalef mandala", a new conceptual model or mandala is presented here. The new mandala maps twelve response or effects traits, or environmental characteristics, related to different phytoplankton functional types: (1) relative preference for chemically reduced vs chemically oxidized forms of nitrogen; (2) relative availability of inorganic nitrogen and phosphorus; (3) adaptation to high vs low light and the tendency to be autotrophic vs mixotrophic; (4) cell motility; (5) environmental turbulence; (6) pigmentation quality; (7) temperature; (8) cell size; (9) relative growth rate; (10) relative production of bioactive compounds such as toxins or reactive oxygen species (ROS); (11) r vs K strategy; and (12) fate of the production in terms of grazing. The new mandala serves to highlight the differences and trade-offs between traits and/or environmental conditions, and illustrates some traits tend to track each other, a concept that may be helpful in trait-based modeling approaches and in understanding environmental factors associated with harmful algal blooms. It is hoped that this new mandala captures some of our recent insight into phytoplankton physiology and functional traits, and has contemporary relevance in light of anthropogenic changes in nutrient form and ratio. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Margalef revisited: A new phytoplankton mandala incorporating twelve dimensions, including nutrient ratios and forms (United States)

    Glibert, P. M.


    Building on the classic depiction of the progression from a diatom to a dinoflagellate bloom as a function of nutrients and turbulence, known as the "Margalef mandala", a new conceptual model or mandala is presented here. The new mandala maps twelve traits or environmental characteristics related to different phytoplankton functional types: (1) relative preference for chemically reduced vs chemically oxidized forms of nitrogen; (2) relative availability of inorganic nitrogen and phosphorus; (3) adaptation to high vs low light and the tendency to be autotrophic vs mixotrophic; (4) cell motility; (5) environmental turbulence; (6) pigmentation quality; (7) temperature; (8) cell size; (9) relative growth rate; (10) relative production of bioactive compounds such as toxins or reactive oxygen species (ROS); (11) r vs K strategy; and (12) fate of the production in terms of grazing. The new mandala serves to highlight the differences and trade-offs between traits and/or environmental conditions, and illustrates some traits tend to track each other, a concept that may be helpful in trait-based modeling approaches. It is hoped that this new mandala captures some of our recent insight into phytoplankton physiology and functional traits, and has contemporary relevance in light of anthropogenic changes in nutrient form and ratio.

  5. Review of the Spirobolida on Madagascar, with descriptions of twelve new genera, including three genera of 'fire millipedes' (Diplopoda

    Directory of Open Access Journals (Sweden)

    Thomas Wesener


    Full Text Available Twelve new genera and 37 new species of Spirobolida are described: Corallobolus cruentus gen. n., sp. n., Sanguinobolus maculosus gen. n., sp. n., Colossobolus semicyclus gen. n., sp. n., C. oblongopedus sp. n., C. giganteus sp. n., C. minor sp. n., C. litoralis sp. n., C. aculeatus sp. n., C. pseudoaculeatus sp. n., Zehntnerobolus gen. n., Flagellobolus pauliani gen. n., sp. n., Riotintobolus mandenensis gen. n., sp. n., R. minutus sp. n., R. aridus sp. n., R. anomalus sp. n., Pseudocentrobolus aureus gen. n., sp. n., P. vohibasiensis sp. n., Granitobolus endemicus gen. n., sp. n., G. andohahelensis sp. n., Caprobolus andringitra gen. n., sp. n., Alluviobolus laticlavius gen. n., sp. n., A. tsimelahy sp. n., A. antanosy sp. n., Ostinobolus rufus gen. n., sp. n., O. stellaris sp. n., O. montanus sp. n., O. subterraneus sp. n., and Hylekobolus brachiosauroides gen. n., sp. n., H. rufus sp. n., H. griseus sp. n., H. albicollaris sp. n., H. goodmani sp. n., H. montanus sp. n., H. analavelona sp. n., H. latifrons sp. n., H. andasibensis sp. n., H. marojejy sp. n., H. anjanaharibe sp. n. All genera and species are endemic to Madagascar. Hylekobolus belongs to the family Spirobolellidae, while all other Malagasy genera of Spirobolida belong to the Pachybolidae. Among them, only Zehntnerobolus gen. n. is based on a previously described species: Spirobolus rubripes de Saussure & Zehntner, 1897, whereas the remaining 11 new genera altogether contain (a total of 37 new species. Three of the new genera are large-bodied “fire millipedes” (>100 mm long with striking red/black colour patterns. The new discoveries increase the number of endemic Malagasy genera of Spirobolida more than fivefold (from 3 to 15. The number of endemic species recorded from Madagascar has more than doubled (to 61. Body length of the new species varies greatly (between 23 and 170 mm. Keys to all Malagasy Spirobolida families, genera, as well as the newly described species

  6. Chapter Houses, Navajo Nation, 2007 (United States)

    U.S. Environmental Protection Agency — This GIS dataset contains point features representing Chapter Houses in the Navajo Nation. Chapter Name is included in the Attributes. This dataset contains 111...


    North Carolina General Assembly, Raleigh.


  8. Chapter 9: Electronics


    Spieler, Helmuth G


    Sophisticated front-end electronics are a key part of practically all modern radiation detector systems. This chapter introduces the basic principles and their implementation. Topics include signal acquisition, electronic noise, pulse shaping (analog and digital), and data readout techniques.

  9. Chapter 9: Electronics

    Energy Technology Data Exchange (ETDEWEB)

    Grupen, Claus; Shwartz, Boris A.


    Sophisticated front-end electronics are a key part of practically all modern radiation detector systems. This chapter introduces the basic principles and their implementation. Topics include signal acquisition, electronic noise, pulse shaping (analog and digital), and data readout techniques.

  10. Chapter 9: Electronics

    Energy Technology Data Exchange (ETDEWEB)

    Grupen, Claus; Shwartz, Boris A.


    Sophisticated front-end electronics are a key part of practically all modern radiation detector systems. This chapter introduces the basic principles and their implementation. Topics include signal acquisition, electronic noise, pulse shaping (analog and digital), and data readout techniques.

  11. Chapter 9: Reliability

    Energy Technology Data Exchange (ETDEWEB)

    Algora, Carlos; Espinet-Gonzalez, Pilar; Vazquez, Manuel; Bosco, Nick; Miller, David; Kurtz, Sarah; Rubio, Francisca; McConnell,Robert


    This chapter describes the accumulated knowledge on CPV reliability with its fundamentals and qualification. It explains the reliability of solar cells, modules (including optics) and plants. The chapter discusses the statistical distributions, namely exponential, normal and Weibull. The reliability of solar cells includes: namely the issues in accelerated aging tests in CPV solar cells, types of failure and failures in real time operation. The chapter explores the accelerated life tests, namely qualitative life tests (mainly HALT) and quantitative accelerated life tests (QALT). It examines other well proven and experienced PV cells and/or semiconductor devices, which share similar semiconductor materials, manufacturing techniques or operating conditions, namely, III-V space solar cells and light emitting diodes (LEDs). It addresses each of the identified reliability issues and presents the current state of the art knowledge for their testing and evaluation. Finally, the chapter summarizes the CPV qualification and reliability standards.

  12. The British research evidence for recovery, papers published between 2006 and 2009 (inclusive). Part two: a review of the grey literature including book chapters and policy documents. (United States)

    Stickley, T; Wright, N


    This paper is the second in a series of two which reviews the current UK evidence base for recovery in mental health. As outlined in the previous paper, over the last 4 years a vast amount has written about recovery in mental health (approximately 60% of all articles). Whereas the first review focused on the peer-reviewed evidence; this paper specifically focuses on the grey/non-peer-reviewed literature. In total, our search strategy yielded the following: 3 books, a further 11 book chapters, 12 papers, 6 policy documents and 3 publications from voluntary sector organizations. Each group of publications was analysed for content, and they are discursively presented by publication group. The findings are then presented as themes in the discussion section. The themes are: social, historical and political critique; philosophy of hope for the individual; individual identity and narrative; models and guidance for mental health practice. We conclude that there is a need for both empirical research into recovery and a clearer theoretical exposition of the concept.

  13. Human Evolution in Science Textbooks from Twelve Different Countries (United States)

    Quessada, Marie-Pierre; Clement, Pierre; Oerke, Britta; Valente, Adriana


    What kinds of images of human beings illustrate human evolution in school textbooks? A comparison between the textbooks of eighteen different countries (twelve European countries and six non-European countries) was attempted. In six countries (Algeria, Malta, Morocco, Mozambique, Portugal, and Tunisia), we did not find any chapter on the topic of…

  14. Epidemiology chapter. (United States)

    Wolfram, J H; Butaev, M K; Duysheev, A; Gabbasova, A R; Khasanov, O S; Kulakov, Yu K; Mkrtchyan, A R; Myrzabekov, A M; Nurgaziev, R Z; Tsirel'son, L E; Willer, R D; Yaraev, R G; Zheludkov, M M


    This chapter outlines the epidemiology of brucellosis in the Russian Federation and in five countries bordering Russia. Since the Soviet Union's dissolution, Russia and the newly formed independent republics have failed to maintain policies to control brucellosis and other zoonotic diseases. Many of these republics, due to weak animal control and prevention systems and dangerous food preparation practices, are still burdened with the human cost of brucellosis. The final summary of this section provides an example of the successful transboundary cooperative efforts between Arizona and Mexico, which could be applied to the situation between Russia and the bordering independent republics.

  15. Nursery management [Chapter 16 (United States)

    Kim M. Wilkinson


    This handbook provides an overview of the factors that go into starting and operating a native plant nursery. Management includes all aspects of working with plants in all their phases of growth as described in Chapter 3, Crop Planning and Developing Propagation Protocols. Management also includes working with the community; organizing materials and infrastructure;...

  16. Twelve lectures on structural dynamics

    CERN Document Server

    Preumont, André


    This text addresses the modeling of vibrating systems with the perspective of finding the model of minimum complexity which accounts for the physics of the phenomena at play. The first half of the book (Ch.1-6) deals with the dynamics of discrete and continuous mechanical systems; the classical approach emphasizes the use of Lagrange's equations. The second half of the book (Ch.7-12) deals with more advanced topics, rarely encountered in the existing literature: seismic excitation, random vibration (including fatigue), rotor dynamics, vibration isolation and dynamic vibration absorbers; the final chapter is an introduction to active control of vibrations. The first part of this text may be used as a one semester course for 3rd year students in Mechanical, Aerospace or Civil Engineering. The second part of the text is intended for graduate classes. A set of problems is provided at the end of every chapter. The author has a 35 years experience in various aspects of Structural dynamics, both in industry (nuclea...

  17. Chapter 3: Energy Security

    Energy Technology Data Exchange (ETDEWEB)

    Foust, Thomas D.; Arent, Doug; de Carvalho Macedo, Isaias; Goldemberg, Jose; Hoysala, Chanakya; Filho, Rubens Maciel; Nigro, Francisco E. B.; Richard, Tom L.; Saddler, Jack; Samseth, Jon; Somerville, Chris R.


    This chapter considers the energy security implications and impacts of bioenergy. We provide an assessment to answer the following questions: What are the implications for bioenergy and energy security within the broader policy environment that includes food and water security, development, economic productivity, and multiple foreign policy aspects? What are the conditions under which bioenergy contributes positively to energy security?

  18. The Twelve Hotel, Barna : Video


    Irish Food Channel


    Fergus O'Halloran, Managing Director of The Twelve Hotel in Barna in County Galway, talks about his philosophy in running this unique boutique hotel. Reproduced with kind permission from John & Sally McKenna. 3.35 mins

  19. Coal and petroleum resources in the Appalachian basin: index maps of included studies: Chapter B.1 in Coal and petroleum resources in the Appalachian basin: distribution, geologic framework, and geochemical character (United States)

    Ruppert, Leslie F.; Trippi, Michael H.; Kinney, Scott A.; Ruppert, Leslie F.; Ryder, Robert T.


    This chapter B.1 of U.S. Geological Survey (USGS) Professional Paper 1708 provides index maps for many of the studies described in other chapters of the report. Scientists of the USGS and State geological surveys studied coal and petroleum resources in the central and southern Appalachian structural basins. In the southern Appalachian basin, studies focused on the coal-bearing parts of the Black Warrior basin in Alabama. The scientists used new and existing geologic data sets to create a common spatial geologic framework for the fossil-fuel-bearing strata of the central Appalachian basin and the Black Warrior basin in Alabama.

  20. The impact of alcoholics anonymous on other substance abuse-related twelve-step programs. (United States)

    Laudet, Alexandre B


    This chapter explores the influence of the AA model on self-help fellowships addressing problems of drug dependence. Fellowships that have adapted the twelve-step recovery model to other substances of abuse are reviewed; next similarities and differences between AA and drug-recovery twelve-step organizations are examined; finally, we present empirical findings on patterns of attendance and perceptions of AA and Narcotics Anonymous (NA) among polydrug-dependent populations, many of whom are cross-addicted to alcohol. Future directions in twelve-step research are noted in closing.

  1. Chapter 7: Microalgae

    Energy Technology Data Exchange (ETDEWEB)

    Efroymson, Rebecca; Coleman, Andre; Wigmosta, Mark; Schoenung, Susan; Sokhansanj, Shahab; Langholtz, Matthew; Davis, Ryan


    This chapter of the 2016 Billion-Ton Report provides an estimate of biomass potential at given minimum selling prices. This is not a projection of actual measured biomass or a simulation of commercial projects. Biomass potential is estimated based on 30 years of hourly local climate and strain-specific biophysical characteristics using the Biomass Assessment Tool (BAT), assuming sufficient available nutrients (including CO2). As is the case for terrestrial feedstocks, important resource analysis questions for algae include not only how much of the crop may be available but also what price might be needed to procure that supply. Identifying resource co-location opportunities for algal biofuel facilities has the potential to reduce costs, utilize waste resources, and focus attention on appropriate technologies and locations for commercialization.

  2. Various chapter styles for the memoir class

    DEFF Research Database (Denmark)

    Madsen, Lars


    Document showcasing various chapter title page designs either included in the LaTeX memoir class or is easily manually coded.......Document showcasing various chapter title page designs either included in the LaTeX memoir class or is easily manually coded....

  3. Chapter 1: Direct Normal Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Myer, Daryl R.


    This chapter addresses the quantitative and qualitative aspects of the solar resource, the direct solar radiation. It discusses the total or integrated broadband direct beam extraterrestrial radiation (ETR). This total integrated irradiance is comprised of photons of electromagnetic radiation. The chapter also discusses the impact of the atmosphere and its effect upon the direct normal irradiance (DNI) beam radiation. The gases and particulates present in the atmosphere traversed by the direct beam reflect, absorb, and scatter differing spectral regions and proportions of the direct beam, and act as a variable filter. Knowledge of the available broadband DNI beam radiation resource data is essential in designing a concentrating photovoltaic (CPV) system. Spectral variations in the DNI beam radiation affect the performance of a CPV system depending on the solar cell technology used. The chapter describes propagation and scattering processes of circumsolar radiation (CSR), which includes the Mie scattering from large particles.

  4. Chapter Four: Discursive Resources (United States)

    Young, Richard F.


    In this chapter, the focus of attention moves from the contexts described in chapter 3 to the verbal, nonverbal, and interactional resources that participants employ in discursive practices. These resources are discussed within the frame of participation status and participation framework proposed by Goffman. Verbal resources employed by…

  5. Transanal rectopexy - twelve case studies

    Directory of Open Access Journals (Sweden)

    Rubens Henrique Oleques Fernandes


    Full Text Available OBJECTIVES: This study analyzed the results of transanal rectopexy and showed the benefits of this surgical technique. METHOD: Twelve patients were submitted to rectopexy between 1997 and 2011. The surgical technique used was transanal rectopexy, where the mesorectum was fixed to the sacrum with nonabsorbable suture. Three patients had been submitted to previous surgery, two by the Delorme technique and one by the Thiersch technique. RESULTS: Postoperative hospital stay ranged from 1 to 4 days. One patient (8.3% had intraoperative hematoma, which was treated with local compression and antibiotics. One patient (8.3% had residual mucosal prolapse, which was resected. Prolapse recurrence was seen in one case (8.3%. Improved incontinence occurred in 75% of patients and one patient reported obstructed evacuation in the first month after surgery. No death occurred. CONCLUSION: Transanal rectopexy is a simple, low cost technique, which has shown good efficacy in rectal prolapse control.OBJETIVO: O presente estudo analisou os resultados da retopexia pela via transanal e expôs os benefícios desta técnica cirúrgica. MÉTODO: Doze pacientes com prolapso foram operados no período de 1997 a 2011. A técnica cirúrgica usada foi a retopexia transanal, onde o mesorreto foi fixado ao sacro com fio inabsorvível. Três pacientes tinham cirurgia prévia, dois pela técnica de Delorme e um pela técnica de Thiersch. RESULTADOS: A permanência hospitalar pós-operatória variou de 1- 4 dias. Uma paciente (8,3% apresentou hematoma transoperatório que foi tratado com compressão local e antibioticoterapia. Um paciente apresentou prolapso mucoso residual (8,3%, que foi ressecado. Houve recidiva da procidência em um caso (8,3%. A melhora da incontinência ocorreu em 75% dos pacientes e uma paciente apresentou bloqueio evacuatório no primeiro mês após a cirurgia. Não houve mortalidade entre os pacientes operados. CONCLUSÃO: A retopexia transanal é uma t

  6. Combining ability of twelve maize populations

    Directory of Open Access Journals (Sweden)

    Vacaro Elton


    Full Text Available Genetic progress depends on germplasm quality and breeding methods. Twelve maize populations and their crosses were evaluated to estimate combining ability and potential to be included as source populations in breeding programs. Plant height, point of insertion of the first ear, number of ears per plant, number of grains per ear, root and stalk lodging and grain yield were studied in two locations in Brazil, during the 1997/98 season. Genotype sum of squares was divided into general (GCA and specific (SCA combining ability. Results indicated the existence of genetic divergence for all traits analyzed, where additive effects were predominant. The high heterosis levels observed, mainly in Xanxerê, suggested the environmental influence on the manifestation of this genetic phenomenon. Populations revealed potential to be used in breeding programs; however, those more intensively submitted to selection could provide larger genetic progress, showing the importance of population improvement for the increment of the heterosis in maize.

  7. Basic Principles - Chapter 6 (United States)

    National Aeronautics and Space Administration — This chapter described at a very high level some of the considerations that need to be made when designing algorithms for a vehicle health management application....

  8. The twelve dimensional super (2+2)-brane

    CERN Document Server

    Hewson, S F


    We discuss supersymmetry in twelve dimensions and present a covariant supersymmetric action for a brane with worldsheet signature (2,2), called a super (2+2)-brane, propagating in the osp(64,12) superspace. This superspace is explicitly constructed, and is trivial in the sense that the spinorial part is a trivial bundle over spacetime, unlike the twisted superspace of usual Poincare supersymmetry. For consistency, it is necessary to take a projection of the superspace. This is the same as the projection required for worldvolume supersymmetry. Upon compactification of this superspace, a torsion is naturally introduced and we produce the membrane and type IIB string actions in 11 and 10 dimensional Minkowski spacetimes. In addition, the compactification of the twelve dimensional supersymmetry algebra produces the correct algebras for these theories, including central charges. These considerations thus give the type IIB string and M-theory a single twelve dimensional origin.

  9. Family Textbooks Twelve Years Later (United States)

    Glenn, Norval D.


    In 1996 the author conducted an intensive study of twenty current family textbooks published in the United States, the results of which appeared in an academic journal article and a nonacademic report in 1997. The study included practical "functionalist" marriage and family textbooks and more academic sociology of the family books; these…

  10. Chapter 42. Waterborne and Foodborne Parasites (United States)

    This chapter identifies the most prominent parasites in North America that are acquired through contaminated food and water including protozoa (Acanthamoeba, Naegleria, Entamoeba, Giardia, Cryptosporidium, Cystoisospora, Cyclospora, Toxoplasma, and Balantidium), nematodes (Trichinella, Angiostrongyl...

  11. Tourette Association Chapters (United States)

    ... Adultos Tics en público: 8 formas de manejarlos Empleo: Como conseguir trabajo y conservarlo Redes Sociales Educación ... Website: New Mexico New Mexico Chapter Email: Website: ...

  12. Sustainable careers: Introductory chapter

    NARCIS (Netherlands)

    Heijden, B.I.J.M. van der; Vos, A de


    In this introductory chapter we will introduce the concept of ‘sustainable careers’ within the broader framework of contemporary careers. Departing from changes in the career context with regard to the dimensions of time, social space, agency and meaning, we advocate a fresh perspective on careers t

  13. Hurrah for Chapter Books. (United States)

    Jones, Glenowyn L.

    This annotated bibliography contains a list of 42 recent Chapter Books. The bibliography is divided into the following topics: Adventure-Survival (3 titles); Autobiography-Biography (3 titles); Death (1 title); Easy Readers (8 titles); Good Reading (12 titles); Historical Fiction (10 titles); Mystery (3 titles); Newbery Award Winner, 2000; and…

  14. Chapter 8. Data Analysis (United States)

    Lyman L. McDonald; Christina D. Vojta; Kevin S. McKelvey


    Perhaps the greatest barrier between monitoring and management is data analysis. Data languish in drawers and spreadsheets because those who collect or maintain monitoring data lack training in how to effectively summarize and analyze their findings. This chapter serves as a first step to surmounting that barrier by empowering any monitoring team with the basic...

  15. Water resources (Chapter 12) (United States)

    Thomas C. Brown; Romano Foti; Jorge Ramirez


    In this chapter, we focus on the vulnerability of U.S. freshwater supplies considering all lands, not just forest and rangelands. We do not assess the condition of those lands or report on how much of our water supply originates on lands of different land covers or ownerships, because earlier Resources Planning Act (RPA) Assessment work addressed these topics....

  16. Secondary School Mathematics, Chapter 13, Perpendiculars and Parallels (I), Chapter 14, Similarity. Student's Text. (United States)

    Stanford Univ., CA. School Mathematics Study Group.

    The first chapter of the seventh unit in this SMSG series discusses perpendiculars and parallels; topics covered include the relationship between parallelism and perpendicularity, rectangles, transversals, parallelograms, general triangles, and measurement of the circumference of the earth. The second chapter, on similarity, discusses scale…

  17. Mythematics Solving the Twelve Labors of Hercules

    CERN Document Server

    Huber, Michael


    How might Hercules, the most famous of the Greek heroes, have used mathematics to complete his astonishing Twelve Labors? From conquering the Nemean Lion and cleaning out the Augean Stables, to capturing the Erymanthean Boar and entering the Underworld to defeat the three-headed dog Cerberus, Hercules and his legend are the inspiration for this book of fun and original math puzzles. While Hercules relied on superhuman strength to accomplish the Twelve Labors, Mythematics shows how math could have helped during his quest. How does Hercules defeat the Lernean Hydra and stop its heads from multip

  18. Scenarios and activities (Chapter 1)

    CSIR Research Space (South Africa)

    Burns, Mike


    Full Text Available The description and quantification of the shale gas-related activities presented in this Chapter informs the assessment of ecological and social risk addressed in other Chapters. For the Exploration Only scenario, activities that will manifest...

  19. Organic-Carbon Sequestration in Soil/Sediment of the Mississippi River Deltaic Plain - Data; Landscape Distribution, Storage, and Inventory; Accumulation Rates; and Recent Loss, Including a Post-Katrina Preliminary Analysis (Chapter B) (United States)

    Markewich, Helaine W.; Buell, Gary R.; Britsch, Louis D.; McGeehin, John P.; Robbins, John A.; Wrenn, John H.; Dillon, Douglas L.; Fries, Terry L.; Morehead, Nancy R.


    Soil/sediment of the Mississippi River deltaic plain (MRDP) in southeastern Louisiana is rich in organic carbon (OC). The MRDP contains about 2 percent of all OC in the surface meter of soil/sediment in the Mississippi River Basin (MRB). Environments within the MRDP differ in soil/sediment organic carbon (SOC) accumulation rate, storage, and inventory. The focus of this study was twofold: (1) develop a database for OC and bulk density for MRDP soil/sediment; and (2) estimate SOC storage, inventory, and accumulation rates for the dominant environments (brackish, intermediate, and fresh marsh; natural levee; distributary; backswamp; and swamp) in the MRDP. Comparative studies were conducted to determine which field and laboratory methods result in the most accurate and reproducible bulk-density values for each marsh environment. Sampling methods included push-core, vibracore, peat borer, and Hargis1 sampler. Bulk-density data for cores taken by the 'short push-core method' proved to be more internally consistent than data for samples collected by other methods. Laboratory methods to estimate OC concentration and inorganic-constituent concentration included mass spectrometry, coulometry, and loss-on-ignition. For the sampled MRDP environments, these methods were comparable. SOC storage was calculated for each core with adequate OC and bulk-density data. SOC inventory was calculated using core-specific data from this study and available published and unpublished pedon data linked to SSURGO2 map units. Sample age was estimated using isotopic cesium (137Cs), lead (210Pb), and carbon (14C), elemental Pb, palynomorphs, other stratigraphic markers, and written history. SOC accumulation rates were estimated for each core with adequate age data. Cesium-137 profiles for marsh soil/sediment are the least ambiguous. Levee and distributary 137Cs profiles show the effects of intermittent allochthonous input and/or sediment resuspension. Cesium-137 and 210Pb data gave the most

  20. Chemical Tracer Methods: Chapter 7 (United States)

    Healy, Richard W.


    Tracers have a wide variety of uses in hydrologic studies: providing quantitative or qualitative estimates of recharge, identifying sources of recharge, providing information on velocities and travel times of water movement, assessing the importance of preferential flow paths, providing information on hydrodynamic dispersion, and providing data for calibration of water flow and solute-transport models (Walker, 1998; Cook and Herczeg, 2000; Scanlon et al., 2002b). Tracers generally are ions, isotopes, or gases that move with water and that can be detected in the atmosphere, in surface waters, and in the subsurface. Heat also is transported by water; therefore, temperatures can be used to trace water movement. This chapter focuses on the use of chemical and isotopic tracers in the subsurface to estimate recharge. Tracer use in surface-water studies to determine groundwater discharge to streams is addressed in Chapter 4; the use of temperature as a tracer is described in Chapter 8.Following the nomenclature of Scanlon et al. (2002b), tracers are grouped into three categories: natural environmental tracers, historical tracers, and applied tracers. Natural environmental tracers are those that are transported to or created within the atmosphere under natural processes; these tracers are carried to the Earth’s surface as wet or dry atmospheric deposition. The most commonly used natural environmental tracer is chloride (Cl) (Allison and Hughes, 1978). Ocean water, through the process of evaporation, is the primary source of atmospheric Cl. Other tracers in this category include chlorine-36 (36Cl) and tritium (3H); these two isotopes are produced naturally in the Earth’s atmosphere; however, there are additional anthropogenic sources of them.

  1. Twelve years of Neandertal genetic discoveries

    DEFF Research Database (Denmark)

    Orlando, Ludovic Antoine Alexandre; Hänni, Catherine


    specimens have delivered authentic mitochondrial sequences. This information has helped us to better understand the evolution of the Neandertal gene pool over space and time and to address the long-standing question of possible admixture with their modern human relatives. This chapter reviews current...

  2. Comparative analysis of twelve Dothideomycete plant pathogens

    Energy Technology Data Exchange (ETDEWEB)

    Ohm, Robin; Aerts, Andrea; Salamov, Asaf; Goodwin, Stephen B.; Grigoriev, Igor


    The Dothideomycetes are one of the largest and most diverse groups of fungi. Many are plant pathogens and pose a serious threat to agricultural crops grown for biofuel, food or feed. Most Dothideomycetes have only a single host and related Dothideomycete species can have very diverse host plants. Twelve Dothideomycete genomes have currently been sequenced by the Joint Genome Institute and other sequencing centers. They can be accessed via Mycocosm which has tools for comparative analysis

  3. Chapter 8: Youth Culture

    DEFF Research Database (Denmark)

    Stald, Gitte Bang


    Gitte Stald has been researching mobile technologies since their early days of adoption by younger audiences. In her talk, she focuses on adolescents and their mobile media use. Stald shares her findings from the longitudinal and cross-cultural studies she has been conducting over the years....... The chapter builds on findings from a Danish and a European context, but they can be expanded to think about mobile youth culture in general. Gitte Stald discusses the concepts of digital natives and digital immigrants, sharing, immediacy, and the feeling of presence (or absent presence), social coordination...... how they allow youth carefully to curate and update the identities they project online, on the go and in real time. As such, Stald argues that mobile phones act as mediators for social engagement and sharing of personal information with others. Growing up with the technology, newer generations view...

  4. CHAPTER 1. Introduction

    KAUST Repository

    Zhang, Lianbin


    With the development of modern industry and modern economies, environmental problems, especially water pollution and water scarcity, have become the most serious global challenges. In dealing with these challenges, various kinds of functionalized materials and devices are purposefully developed, fabricated, and utilized. It is clear that smart materials have not only provided effective strategies for solving environmental problems, but have also exhibited unprecedented advantages over traditional materials by integrating multifunctions and/or processes into one advanced device/material. In this book, we will present a broad collection of bioinspired smart materials and systems that are used in environmental problem solving. The topics of these chapters span from bioinspired fog collection, self-healing materials, responsive particle-stabilized emulsions, smart draw solutions in forward osmosis, slippery coating, insightful analysis of problems and opportunities for hydrophobic surfaces applied in real conditions, to superwetting materials for oil-water separation.

  5. Chapter 6: Temperature (United States)

    Jones, Leslie A.; Muhlfeld, Clint C.; Hauer, F. Richard; F. Richard Hauer,; Lamberti, G.A.


    Stream temperature has direct and indirect effects on stream ecology and is critical in determining both abiotic and biotic system responses across a hierarchy of spatial and temporal scales. Temperature variation is primarily driven by solar radiation, while landscape topography, geology, and stream reach scale ecosystem processes contribute to local variability. Spatiotemporal heterogeneity in freshwater ecosystems influences habitat distributions, physiological functions, and phenology of all aquatic organisms. In this chapter we provide an overview of methods for monitoring stream temperature, characterization of thermal profiles, and modeling approaches to stream temperature prediction. Recent advances in temperature monitoring allow for more comprehensive studies of the underlying processes influencing annual variation of temperatures and how thermal variability may impact aquatic organisms at individual, population, and community based scales. Likewise, the development of spatially explicit predictive models provide a framework for simulating natural and anthropogenic effects on thermal regimes which is integral for sustainable management of freshwater systems.

  6. Chapter 5. Morphology: Pronouns


    Nesset, Tore


    Have you ever wondered whether the so-called reflexive postfix ‑ся is related to the reflexive pronoun себя? Do you know the etymology of сейчас and сегодня? And do you know where the н in the pronoun comes from in prepositional phrases like к нему ‘to him’? Answers to these and many other questions are offered in this chapter, which explores the declension of personal pronouns (sections 5.1 and 5.2), demonstrative pronouns (section 5.3), possessive pronouns (section 5.4), вьсь ‘all’ (section...

  7. Twelve tips for peer observation of teaching. (United States)

    Siddiqui, Zarrin Seema; Jonas-Dwyer, Diana; Carr, Sandra E


    This paper outlines twelve tips for undertaking peer observation of teaching in medical education, using the peer review model and the experiences of the authors. An accurate understanding of teaching effectiveness is required by individuals, medical schools, and universities to evaluate the learning environment and to substantiate academic and institutional performance. Peer Observation of Teaching is one tool that provides rich, qualitative evidence for teachers, quite different from closed-ended student evaluations. When Peer Observation of Teaching is incorporated into university practice and culture, and is conducted in a mutually respectful and supportive way, it has the potential to facilitate reflective change and growth for teachers.

  8. Career development through local chapter involvement: perspectives from chapter members. (United States)

    Thomas, Melissa; Inniss-Richter, Zipporah; Mata, Holly; Cottrell, Randall R


    The importance of career development in professional organizations has been noted in the literature. Personal and professional benefits of membership regardless of discipline can be found across the career spectrum from student to executive. The benefits of professional membership with respect to career development in local chapter organizations have seldom been studied. Local chapter participation may offer significant career development opportunities for the practitioner, faculty member, and student. The purpose of this study was to explore the importance of local chapter involvement to the career development of health education practitioners. An 18-item questionnaire was disseminated to the membership of three local SOPHE (Society for Public Health Education) chapters that explored the level of local chapter involvement and the impact of how specific professional development activities impacted career development. The results of the survey highlighted the importance of continuing education programs, networking, and leadership experience in developing one's career that are offered by local SOPHE chapter involvement. Making a positive impact in the community and earning the respect of one's peers were most often reported as indicators of career success. These factors can directly impact local chapter participation. Career development can certainly be enhanced by active participation in the local chapter of a professional association.

  9. Synthesis: Chapter 19 (United States)

    Pardo, L.H.; Geiser, L.H.; Fenn, M.E.; Driscoll, C.T.; Goodale, C.L.; Allen, E.B.; Baron, J. S.; Bobbink, R.; Bowman, W.D.; Clark, C.M.; Emmett, B.; Gilliam, F.S.; Greaver, T.; Hall, S.J.; Lilleskov, E.A.; Liu, L.; Lynch, J.A.; Nadelhoffer, K.; Perakis, S.S.; Robin-Abbott, M. J.; Stoddard, J.L.; Weathers, K. C.


    Human activity in the last century has led to a substantial increase in nitrogen (N) emissions and deposition (Galloway et al. 2003). Because of past, and, in some regions, continuing increases in emissions (Lehmann et al. 2005, Nilles and Conley 2001), this N deposition has reached a level that has caused or is likely to cause alterations and damage in many ecosystems across the United States. In some ecoregions, the impact of N deposition has been severe and has changed the biotic community structure and composition of ecosystems. In the Mediterranean California ecoregion, for example (see Chapter 13), replacement of native by exotic invasive vegetation is accelerated because exotic species are often more productive under elevated N deposition than native species in some California grasslands, coastal sage scrub, and desert scrub (Fenn et al. 2010, Rao and Allen 2010, Rao et al. 2010, Weiss 1999, Yoshida and Allen 2004). Such shifts in plant community composition and species richness can have consequences beyond changes in ecosystem structure: shifts may lead to overall losses in biodiversity and further impair particular threatened or endangered species (Stevens et al. 2004). Th e extirpation of the endangered checkerspot butterfl y (Euphydryas editha bayensis), because the host plant for the larval stage disappears in N-enriched ecosystems (Fenn et al. 2010, Weiss 1999), is just one example of the detrimental impacts of elevated N deposition.

  10. Towards the next chapter

    CERN Multimedia


    In the late 1970s, while the CERN community was busy preparing the SPS to operate as a collider and planning for LEP, people also had their eyes on the next chapter in the unfolding story of CERN.   That the LEP tunnel should be built with a future hadron collider in mind was a given by the end of the decade. But there had also been proposals to build large proton storage rings, or re-equip the ISR with superconducting magnets. Some people had suggested building an electron-proton collider at CERN, and there were ambitious plans looking far into the future at a possible Very Big Accelerator to be built somewhere in the world, which went by its acronym VBA. For the field of particle physics, with its very long lead times, this is part of the normal cycle, and while most of those options never came to fruition, this process did pave the way for the LHC. Today, with the LHC programme underway, the time has come for CERN to start seriously considering the options for its post-LHC future. Perhaps ...

  11. Marine West Coast Forests, Chapter 9 (United States)

    Perakis, Steven S.; Geiser, Linda H.; Lilleskov, Erik A.; Pardo, Linda H.; Robin-Abbott, Molly J.; Driscoll, Charles T.


    Human activities have greatly increased nitrogen emissions and deposition across large areas of Earth. Although nitrogen is an essential nutrient for plant growth, too much nitrogen in excess of critical loads leads to losses of biodiversity, soil and stream acidification, nutrient imbalances, and other deleterious effects. In a new report quantifying critical loads of nitrogen deposition across the United States, USGS scientist Steve Perakis and co-authors provided a chapter about responses of marine west coast forests. Much of this region is understudied with respect to nitrogen deposition, and in this chapter the authors identify known adverse effects and estimate critical loads of nitrogen deposition for western Oregon and Washington and southeast Alaska forests. Perakis also contributed to the synthesis chapter, which includes background, objectives, advantages and uncertainties of critical loads, an overview of critical loads across U.S. ecoregions, and other topics.

  12. Chapter 12: spatial or area repellents (United States)

    Spatial repellents a three-dimensional zone of protection around a host from attacks by biting arthropods. This chapter reviews current knowledge and outlines future directions for utilization of spatial repellents. Current knowledge includes the kinds of products, both active and passive devices,...

  13. Chapter 16: Public safety and cognitive radio

    NARCIS (Netherlands)

    Heskamp, M.; Schiphorst, Roelof; Slump, Cornelis H.; Wyglinsk, Alexander M.; Nekovee, Maziar; Hou, Y. Thomas


    This book gives comprehensive and balanced coverage of the principles of cognitive radio communications, cognitive networks, and details of their implementation, including the latest developments in the standards and spectrum policy. Case studies, end-of-chapter questions, and descriptions of variou

  14. Life cycle analysis of biochar [Chapter 3 (United States)

    Richard D. Bergman; Hongmei Gu; Deborah S. Page-Dumroese; Nathaniel M. Anderson


    All products, including bioproducts, have an impact on the environment by consuming resources and releasing emissions during their production. Biochar, a bioproduct, has received considerable attention because of its potential to sequester carbon in soil while enhancing productivity, thus aiding sustainable supply chain development. In this chapter, the environmental...

  15. Explanatory chapter: PCR primer design. (United States)

    Álvarez-Fernández, Rubén


    This chapter is intended as a guide on polymerase chain reaction (PCR) primer design (for information on PCR, see General PCR and Explanatory Chapter: Troubleshooting PCR). In the next section, general guidelines will be provided, followed by a discussion on primer design for specific applications. A list of recommended software tools is shown at the end. Copyright © 2013 Elsevier Inc. All rights reserved.

  16. Collective Intelligence. Chapter 17 (United States)

    Wolpert, David H.


    Many systems of self-interested agents have an associated performance criterion that rates the dynamic behavior of the overall system. This chapter presents an introduction to the science of such systems. Formally, collectives are defined as any system having the following two characteristics: First, the system must contain one or more agents each of which we view as trying to maximize an associated private utility; second, the system must have an associated world utility function that rates the possible behaviors of that overall system. In practice, collectives are often very large, distributed, and support little, if any, centralized communication and control, although those characteristics are not part of their formal definition. A naturally occurring example of a collective is a human economy. One can identify the agents and their private utilities as the human individuals in the economy and the associated personal rewards they are each trying to maximize. One could then identify the world utility as the time average of the gross domestic product. ("World utility" per se is not a construction internal to a human economy, but rather something defined from the outside.) To achieve high world utility it is necessary to avoid having the agents work at cross-purposes lest phenomena like liquidity traps or the Tragedy of the Commons (TOC) occur, in which agents' individually pursuing their private utilities lowers world utility. The obvious way to avoid such phenomena is by modifying the agents utility functions to be "aligned" with the world utility. This can be done via punitive legislation. A real-world example of an attempt to do this was the creation of antitrust regulations designed to prevent monopolistic practices.

  17. Chapter 59: Web Services (United States)

    Graham, M. J.

    Web services are a cornerstone of the distributed computing infrastructure that the VO is built upon yet to the newcomer, they can appear to be a black art. This perception is not helped by the miasma of technobabble that pervades the subject and the seemingly impenetrable high priesthood of actual users. In truth, however, there is nothing conceptually difficult about web services (unsurprisingly any complexities will lie in the implementation details) nor indeed anything particularly new. A web service is a piece of software available over a network with a formal description of how it is called and what it returns that a computer can understand. Note that entities such as web servers, ftp servers and database servers do not generally qualify as they lack the standardized description of their inputs and outputs. There are prior technologies, such as RMI, CORBA, and DCOM, that have employed a similar approach but the success of web services lies predominantly in its use of standardized XML to provide a language-neutral way for representing data. In fact, the standardization goes further as web services are traditionally (or as traditionally as five years will allow) tied to a specific set of technologies (WSDL and SOAP conveyed using HTTP with an XML serialization). Alternative implementations are becoming increasingly common and we will cover some of these here. One important thing to remember in all of this, though, is that web services are meant for use by computers and not humans (unlike web pages) and this is why so much of it seems incomprehensible gobbledegook. In this chapter, we will start with an overview of the web services current in the VO and present a short guide on how to use and deploy a web service. We will then review the different approaches to web services, particularly REST and SOAP, and alternatives to XML as a data format. We will consider how web services can be formally described and discuss how advanced features such as security, state

  18. Grand-Slam Strategies: Winning Tips for Cutting Chapter Costs. (United States)

    Burdette, Melinda


    Techniques for more cost-effective college alumni chapter administration include better marketing and communications, regionally tailored periodicals, planning ahead, coordinating spring volunteer training with admissions travel, encouraging faculty participation, using mentors for program development, letting chapters pay expenses, and better use…

  19. American Red Cross Chapter Regions (United States)

    Department of Homeland Security — The Regions are part of the national field level structure to support chapters. The Regions role is admistrative as well as provides oversight and program technical...

  20. Twelve tips for getting your manuscript published. (United States)

    Cook, David A


    The author shares twelve practical tips on how to navigate the process of getting a manuscript published. These tips, which apply to all fields of academic writing, advise that during the initial preparation phase authors should: (1) plan early to get it out the door; (2) address authorship and writing group expectations up front; (3) maintain control of the writing; (4) ensure complete reporting; (5) use electronic reference management software; (6) polish carefully before they submit; (7) select the right journal; and (8) follow journal instructions precisely. Rejection after the first submission is likely, and when this occurs authors should (9) get it back out the door quickly, but first (10) take seriously all reviewer and editor suggestions. Finally, when the invitation comes to revise and resubmit, authors should (11) respond carefully to every reviewer suggestion, even if they disagree, and (12) get input from others as they revise. The author also shares detailed suggestions on the creation of effective tables and figures, and on how to respond to reviewer critiques.

  1. Antifouling activity of twelve demosponges from Brazil

    Directory of Open Access Journals (Sweden)

    SM. Ribeiro

    Full Text Available Benthic marine organisms are constantly exposed to fouling, which is harmful to most host species. Thus, the production of secondary metabolites containing antifouling properties is an important ecological advantage for sessile organisms and may also provide leading compounds for the development of antifouling paints. High antifouling potential of sponges has been demonstrated in the Indian and Pacific oceans and in the Caribbean and Mediterranean seas. Brazilian sponges remain understudied concerning antifouling activities. Only two scientific articles reported this activity in sponges of Brazil. The objective of this study was to test crude extracts of twelve species of sponges from Brazil against the attachment of the mussel Perna perna through laboratorial assays, and highlight promising species for future studies. The species Petromica citrina, Amphimedon viridis, Desmapsamma anchorata, Chondrosia sp., Polymastia janeirensis, Tedania ignis, Aplysina fulva, Mycale angulosa, Hymeniacidon heliophila, Dysidea etheria, Tethya rubra, and Tethya maza were frozen and freeze-dried before extraction with acetone or dichloromethane. The crude extract of four species significantly inhibited the attachment of byssus: Tethya rubra (p = 0.0009, Tethya maza (p = 0.0039, Petromica citrina (p = 0.0277, and Hymeniacidon heliophila (p = 0.00003. These species, specially, should be the target of future studies to detail the substances involved in the ability antifouling well as to define its amplitude of action.

  2. Twelve Elastic Constants of Betula platyphylla Suk.

    Institute of Scientific and Technical Information of China (English)

    Wang Liyu; Lu Zhenyou


    Wood elastic constants are needed to describe the elastic behaviors of wood and be taken as an important design parameter for wood-based composite materials and structural materials. This paper clarified the relationships between compliance coefficients and engineering elastic constants combined with orthotropic properties of wood, and twelve elastic constants of Betula platyphylla Suk. were measured by electrical strain gauges. Spreading the adhesive quantity cannot be excessive or too little when the strain flakes were glued. If excessive, the glue layer was too thick which would influence the strain flakes' performance, and if too little, glues plastered were not firm, which could not accurately transmit the strain. Wood as an orthotropic material, its modulus of elasticity and poisson's ratios are related by two formulas:μij /Ei =μji /Ej and μij 0.95) between the reciprocal of elastic modulus MOE-1 and the square of the ratio of depth to length (h/l)2, which indicate that shear modulus values measured were reliable by three point bending experiment.

  3. Secondary School Mathematics, Chapter 15, The Real Number System, Chapter 16, Area, Volume, and Computation. Student's Text. (United States)

    Stanford Univ., CA. School Mathematics Study Group.

    Topics covered in the first chapter of Unit 8 of this SMSG series include square roots, operations with radicals, operations with real numbers, and the structure of the real number system. The second chapter deals with measurement of area (for rectangular regions, other polygons, and circles), volume and surface area, computation involving…

  4. Chapter Twenty Six

    African Journals Online (AJOL)


    wisdom, that is, the results of human efforts to understand life and the ... Some of the characteristics of Hebrew poetry include parallelism, figurative language, .... each line in these 3 verses is really saying the same thing in a repetitive fashion.

  5. Sediment transport measurements: Chapter 5 (United States)

    Diplas, P.; Kuhnle, R.; Gray, J.; Glysson, D.; Edwards, T.; García, Marcelo H.


    Sediment erosion, transport, and deposition in fluvial systems are complex processes that are treated in detail in other sections of this book. Development of methods suitable for the collection of data that contribute to understanding these processes is a still-evolving science. Sediment and ancillary data are fundamental requirements for the proper management of river systems, including the design of structures, the determination of aspects of stream behavior, ascertaining the probable effect of removing an existing structure, estimation of bulk erosion, transport, and sediment delivery to the oceans, ascertaining the long-term usefulness of reservoirs and other public works, tracking movement of solid-phase contaminants, restoration of degraded or otherwise modified streams, and assistance in the calibration and validation of numerical models. This chapter presents techniques for measuring bed-material properties and suspended and bed-load discharges. Well-established and relatively recent, yet adequately tested, sampling equipment and methodologies, with designs that are guided by sound physical and statistical principles, are described. Where appropriate, the theory behind the development of the equipment and guidelines for its use are presented.

  6. Chapter 12: Human microbiome analysis.

    Directory of Open Access Journals (Sweden)

    Xochitl C Morgan

    Full Text Available Humans are essentially sterile during gestation, but during and after birth, every body surface, including the skin, mouth, and gut, becomes host to an enormous variety of microbes, bacterial, archaeal, fungal, and viral. Under normal circumstances, these microbes help us to digest our food and to maintain our immune systems, but dysfunction of the human microbiota has been linked to conditions ranging from inflammatory bowel disease to antibiotic-resistant infections. Modern high-throughput sequencing and bioinformatic tools provide a powerful means of understanding the contribution of the human microbiome to health and its potential as a target for therapeutic interventions. This chapter will first discuss the historical origins of microbiome studies and methods for determining the ecological diversity of a microbial community. Next, it will introduce shotgun sequencing technologies such as metagenomics and metatranscriptomics, the computational challenges and methods associated with these data, and how they enable microbiome analysis. Finally, it will conclude with examples of the functional genomics of the human microbiome and its influences upon health and disease.

  7. Geology [Chapter 4 (United States)

    E. A. Rochette


    The Medicine Bow Mountains have a core of Precambrian rocks. They contain the boundary, the Cheyenne Belt, between the Wyoming Province to the NW and the accreted Proterozoic continental crust to the SE (Karlstrom and Houston 1984). The Wyoming Province consists of Archean rocks that are locally intruded and (or) overlain by rocks of Proterozoic age, including the...

  8. Haramekhala - tantra (the first chapter on medicine). (United States)

    Sharma, P V


    This translation of Haramekhala - tantra of the author is based on Banaras Hindu University manuscript which seems to be a novel one. The manuscript runs into 133 stanzas in all in the form of dialogue between lord Siva and goddess Parvati. This is only the first chapter (of the great work) dealing with medicine. From stanza 109 onwards some magic spells are described and as such those have not been included in this translation.

  9. Hepatic Angiosarcoma: a Review of Twelve Cases

    Institute of Scientific and Technical Information of China (English)

    Qiang Li; Xishan Hao


    OBJECTIVE Hepatic angiosarcoma (HAS), a lethal disease, is the most common sarcoma arising in the liver. Little information about the epidemiology, etiology, diagnosis and management of HAS has been reported. Increased familiarity with this disease will facilitate correct diagnosis and help to improve management of this condition in the future.The objective of this study was to describe cases of hepatic angiosarcoma and to discuss the etiologic, diagnostic, therapeutic features and prognosis of this tumor. This report not only serves to give more evidence of the relationship between hepatic angiosarcoma and carcinogenic exposure, but also demonstrates the key points in different methods of diagnosis and the optimal treatment of hepatic angiosarcoma.METHODS Twelve cases of hepatic angiosareoma were analyzed retrospectively, representing the different character in clinical presentations and laboratory computed tomographical scans; pathological data and treatment are described. Clinical and biologic follow-up was carried out for two years after surgical treatment.RESULTS There were nine men and three women varying in ages from 57 to 71 years with an average of 64.3 years. Ten patientshad a history of exposure to vinyl chloride or thorotrast. Mild or moderate abdominal pain and bloating, abdominal mass and fever were the common clinical presentations. Tumors were visualized by ultrasonography and CT scans in all patients. Biochemical profiles yielded variable results and proved to be of little value in detection or diagnosis. Surgical resection was feasible for each patient who was treated as follows: two wedge resections, six segementectomies and four bisegmentectomies. Five patients received Neoadjuvant chemotherapy postoperatively. The survival rate of those cases was poor. The maximum survival time was fourteen months. The mean survival time for this chemotherapeutic group was 11 months. The difference between the survival time of those treated with an operation

  10. Crystalline systems. [Book chapter

    Energy Technology Data Exchange (ETDEWEB)

    Kispert, L.D.

    The use of two double resonance methods, electron-nuclear double resonance (ENDOR) and electron-electron double resonance (ELDOR) in the study of free radicals in solids is reviewed. Included are descriptions of how crystalline-phase ENDOR is used to determine small hyperfine splittings, quadrupoly couplings, and reaction mechanisms or radical formation and how crystalline phase ELDOR is used to determine large hyperfine splittings, to identify radicals with large quadrupole moments and to study spin exchange processes. The complementary role played by the ENDOR and ELDOR spectroscopy in the separation of overlapping EPR spectra, in the study of proton-deuterium exchange, in the study of methyl groups undergoing tunneling rotation, and in the determination of the rates of intermolecular motion are dealt with. 13 figures, 1 table. (DP)

  11. Spectroscopy of twelve Type Ia supernovae at intermediate redshift

    CERN Document Server

    Balland, C; Pain, R; Walton, N A; Amanullah, R; Astier, Pierre; Ellis, Richard S; Fabbro, S; Goobar, A; Hardin, D; Hook, I M; Irwin, M J; McMahon, R M; Mendez, J M; Ruiz-Lapuente, P; Sainton, G; Schahmaneche, K; Stanishev, V


    We present spectra of twelve Type Ia supernovae obtained in 1999 at the William Herschel Telescope and the Nordic Optical Telescope during a search for Type Ia supernovae (SN Ia) at intermediate redshift. The spectra range from z=0.178 to z=0.493, including five high signal-to-noise ratio SN Ia spectra in the still largely unexplored range 0.15 < z < 0.3. Most of the spectra were obtained before or around restframe B-band maximum light. None of them shows the peculiar spectral features found in low-redshift over- or under-luminous SN Ia. Expansion velocities of characteristic spectral absorption features such as SiII at 6355 angs., SII at 5640 angs. and CaII at 3945 angs. are found consistent with their low-z SN Ia counterparts.

  12. Vaccination against bacterial kidney disease: Chapter 22 (United States)

    Elliott, Diane G.; Wiens, Gregory D.; Hammell, K. Larry; Rhodes, Linda D.; Edited by Gudding, Roar; Lillehaug, Atle; Evensen, Øystein


    Bacterial kidney disease (BKD) of salmonid fishes, caused by Renibacterium salmoninarum, has been recognized as a serious disease in salmonid fishes since the 1930s. This chapter discusses the occurrence and significance, etiology, and pathogenesis of BKD. It then describes the different vaccination procedures and the effects and side-effects of vaccination. Despite years of research, however, only a single vaccine has been licensed for prevention of BKD, and has demonstrated variable efficacy. Therefore, in addition to a presentation of the current status of BKD vaccination, a discussion of potential future directions for BKD vaccine development is included in the chapter. This discussion is focused on the unique characteristics of R. salmoninarum and its biology, as well as aspects of the salmonid immune system that might be explored specifically to develop more effective vaccines for BKD prevention.

  13. Metrology of Large Parts. Chapter 5 (United States)

    Stahl, H. Philip


    As discussed in the first chapter of this book, there are many different methods to measure a part using optical technology. Chapter 2 discussed the use of machine vision to measure macroscopic features such as length and position, which was extended to the use of interferometry as a linear measurement tool in chapter 3, and laser or other trackers to find the relation of key points on large parts in chapter 4. This chapter looks at measuring large parts to optical tolerances in the sub-micron range using interferometry, ranging, and optical tools discussed in the previous chapters. The purpose of this chapter is not to discuss specific metrology tools (such as interferometers or gauges), but to describe a systems engineering approach to testing large parts. Issues such as material warpage and temperature drifts that may be insignificant when measuring a part to micron levels under a microscope, as will be discussed in later chapters, can prove to be very important when making the same measurement over a larger part. In this chapter, we will define a set of guiding principles for successfully overcoming these challenges and illustrate the application of these principles with real world examples. While these examples are drawn from specific large optical testing applications, they inform the problems associated with testing any large part to optical tolerances. Manufacturing today relies on micrometer level part performance. Fields such as energy and transportation are demanding higher tolerances to provide increased efficiencies and fuel savings. By looking at how the optics industry approaches sub-micrometer metrology, one can gain a better understanding of the metrology challenges for any larger part specified to micrometer tolerances. Testing large parts, whether optical components or precision structures, to optical tolerances is just like testing small parts, only harder. Identical with what one does for small parts, a metrologist tests large parts and optics

  14. Twelve Steps toward Revitalization for Teachers. (United States)

    Newbrough, Art


    A dozen common sense ways to respond to and counter the teacher burnout syndrome are briefly discussed. Strategies include physical exercise, stress controls, recultivating special relationships, self-expressions, celebrations, enthusiasm maintenance, and professional support. The aticle is designed to help educators maintain a perspective on…

  15. Twelve new species of Triplocania Roesler (Psocodea: 'Psocoptera': Ptiloneuridae), from South America. (United States)

    Silva Neto, Alberto Moreira Da; Aldrete, Alfonso N García; Rafael, José Albertino


    Twelve species of Triplocania, seven based on male and female specimens and five based on male specimens, are here described and illustrated; nine species are Brazilian, three are Ecuadorian, and one of the latter is shared with Peru. Comments on sexes known and distribution of the species are included.

  16. The Impact of the Financial Crisis on the Content of Twelve Bestselling US Principles of Economics Textbooks

    DEFF Research Database (Denmark)

    Madsen, Poul Thøis


    How have authors of twelve bestselling introductory US textbooks in economics responded to the traumatizing financial crisis? In general the financial crisis is described with a couple of lines here and there or it is dealt with in boxes, separate sections, or specific isolated chapters. Some...... of the textbooks distinguish themselves by also having made some modest qualitative changes of content as a reaction to the financial crisis (especially Colander 2010 and Krugman and Wells 2013). Applying my general analysis of the changes being made already in the twelve textbooks seen as a whole, I discuss how...... any introductory textbook could integrate the financial crisis more adequately into the general presentation, thereby hopefully contributing to enhancing the interest of the students....

  17. Twelve tips for facilitating Millennials' learning. (United States)

    Roberts, David H; Newman, Lori R; Schwartzstein, Richard M


    The current, so-called "Millennial" generation of learners is frequently characterized as having deep understanding of, and appreciation for, technology and social connectedness. This generation of learners has also been molded by a unique set of cultural influences that are essential for medical educators to consider in all aspects of their teaching, including curriculum design, student assessment, and interactions between faculty and learners.  The following tips outline an approach to facilitating learning of our current generation of medical trainees.  The method is based on the available literature and the authors' experiences with Millennial Learners in medical training.  The 12 tips provide detailed approaches and specific strategies for understanding and engaging Millennial Learners and enhancing their learning.  With an increased understanding of the characteristics of the current generation of medical trainees, faculty will be better able to facilitate learning and optimize interactions with Millennial Learners.

  18. Twelve novel Atm mutations identified in Chinese ataxia telangiectasia patients. (United States)

    Huang, Yu; Yang, Lu; Wang, Jianchun; Yang, Fan; Xiao, Ying; Xia, Rongjun; Yuan, Xianhou; Yan, Mingshan


    Ataxia telangiectasia (A-T) is an autosomal recessive disease characterized mainly by progressive cerebellar ataxia, oculocutaneous telangiectasia, and immunodeficiency. This disease is caused by mutations of the ataxia telangiectasia mutated (Atm) gene. More than 500 Atm mutations that are responsible for A-T have been identified so far. However, there have been very few A-T cases reported in China, and only two Chinese A-T patients have undergone Atm gene analysis. In order to systemically investigate A-T in China and map their Atm mutation spectrum, we recruited eight Chinese A-T patients from six unrelated families nationwide. Using direct sequencing of genomic DNA and the multiplex ligation-dependent probe amplification, we identified twelve pathogenic Atm mutations, including one missense, four nonsense, five frameshift, one splicing, and one large genomic deletion. All the Atm mutations we identified were novel, and no homozygous mutation and founder-effect mutation were found. These results suggest that Atm mutations in Chinese populations are diverse and distinct largely from those in other ethnic areas.

  19. Oral papillary squamous cell carcinoma in twelve dogs. (United States)

    Nemec, A; Murphy, B G; Jordan, R C; Kass, P H; Verstraete, F J M


    Papillary squamous cell carcinoma (PSCC) is a distinct histological subtype of oral squamous cell carcinoma (SCC), described in both dogs and man. In dogs, PSCC has long been considered a malignant oral tumour of very young animals, but it has recently been reported to occur in adult dogs as well. The aim of this study was to describe the major clinicopathological characteristics of canine oral PSCC (COPSCC). Twelve dogs diagnosed with COPSCC were included in this retrospective study (1990-2012). The majority (75%) of the dogs were >6 years of age (median age 9 years). All tumours were derived from the gingiva of dentate jaws, with 66.7% affecting the rostral aspects of the jaws. The gross appearance of the lesions varied, with one having an intraosseous component only. The majority (91.7%) of the tumours were advanced lesions (T2 and T3), but no local or distant metastases were noted. Microscopically, two patterns were seen: (1) invasion of bone forming a cup-shaped indentation in the bone or a deeply cavitating cyst within the bone (cavitating pattern), (2) histologically malignant growth, but lack of apparent bone invasion (non-cavitating pattern). The microscopical appearance corresponded to imaging findings in a majority of cases, with cavitating forms presenting with a cyst-like pattern of bone loss or an expansile mass on imaging and non-cavitating forms showing an infiltrative pattern of bone destruction on imaging. These features suggest two distinct biological behaviours of COPSCC.

  20. Sensitivity and growth of twelve Elatior begonia cultivars to ozone

    Energy Technology Data Exchange (ETDEWEB)

    Reinert, R.A.; Nelson, P.V.


    Twelve cultivars of Elatior begonia (Begonia X hiemalis Fotsch.) were exposed to O/sub 3/ at 25 and 50 pphM. The 'Schwabenland' group, 'Whisper 'O' Pink', and 'Improved Krefeld Orange' were the most sensitive, whereas 'Ballerina', 'Mikkell Limelight', and 'Turo' were the least sensitive. 'Rennaisance', 'Heirloom' 'Nixe', and 'Fantasy' were intermediate in sensitivity. The dry weight of foliage (stems plus leaves) of 9 cultivars exposed to O/sub 3/ was significantly less than that of control plants. Ozone at 25 and 50 pphM inhibited flower growth (including peduncles) and development in 4 and 8 of the 12 cultivars, respectively. Differences in flower weight ranged from 43 to 105% of the control at 25 pphM and from 25 to 98% of the control at 50 pphM, depending on cultivar. 1 table.

  1. Fourier Transform Methods. Chapter 4 (United States)

    Kaplan, Simon G.; Quijada, Manuel A.


    This chapter describes the use of Fourier transform spectrometers (FTS) for accurate spectrophotometry over a wide spectral range. After a brief exposition of the basic concepts of FTS operation, we discuss instrument designs and their advantages and disadvantages relative to dispersive spectrometers. We then examine how common sources of error in spectrophotometry manifest themselves when using an FTS and ways to reduce the magnitude of these errors. Examples are given of applications to both basic and derived spectrophotometric quantities. Finally, we give recommendations for choosing the right instrument for a specific application, and how to ensure the accuracy of the measurement results..

  2. Volatile hydrocarbons and fuel oxygenates: Chapter 12 (United States)

    Cozzarelli, Isabelle M.


    Petroleum hydrocarbons and fuel oxygenates are among the most commonly occurring and widely distributed contaminants in the environment. This chapter presents a summary of the sources, transport, fate, and remediation of volatile fuel hydrocarbons and fuel additives in the environment. Much research has focused on the transport and transformation processes of petroleum hydrocarbons and fuel oxygenates, such as benzene, toluene, ethylbenzene, and xylenes and methyl tert‐butyl ether, in groundwater following release from underground storage tanks. Natural attenuation from biodegradation limits the movement of these contaminants and has received considerable attention as an environmental restoration option. This chapter summarizes approaches to environmental restoration, including those that rely on natural attenuation, and also engineered or enhanced remediation. Researchers are increasingly combining several microbial and molecular-based methods to give a complete picture of biodegradation potential and occurrence at contaminated field sites. New insights into the fate of petroleum hydrocarbons and fuel additives have been gained by recent advances in analytical tools and approaches, including stable isotope fractionation, analysis of metabolic intermediates, and direct microbial evidence. However, development of long-term detailed monitoring programs is required to further develop conceptual models of natural attenuation and increase our understanding of the behavior of contaminant mixtures in the subsurface.

  3. Chapter 11: Concentrating Solar Power

    Energy Technology Data Exchange (ETDEWEB)

    Turchi, Craig S [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Stekli, J. [U.S. Department of Energy; Bueno, P. C. [Southwest Research Institute


    This chapter summarizes the applications of the supercritical CO2 (sCO2) Brayton cycle in concentrating solar power (CSP) plants. The design and operation of CSP plants are reviewed to highlight the requirements for the power cycle and attributes that are advantageous for the solar-thermal application. The sCO2 Brayton cycle offers the potential of higher cycle efficiency versus superheated or supercritical steam cycles at temperatures relevant for CSP applications. In addition, Brayton cycle systems using sCO2 are anticipated to have smaller weight and volume, lower thermal mass, and less complex power blocks compared with Rankine cycles due to the higher density of the fluid and simpler cycle design. The simpler machinery and compact size of the sCO2 process may also reduce the installation, maintenance, and operation cost of the system. Power cycle capacities in the range of 10-150 MWe are anticipated for the CSP application. In this chapter, we explore sCO2 Brayton cycle configurations that have attributes that are desirable from the perspective of a CSP application, such as the ability to accommodate dry cooling and daily cycling, as well as integration with thermal energy storage.

  4. Chapter 44: history of neurology in Italy. (United States)

    Bentivoglio, Marina; Mazzarello, Paolo


    The chapter starts from the Renaissance (although the origins of Italian neurology can be traced back to the Middle Ages), when treatises of nervous system physiopathology still followed Hippocratic and Galenic "humoral" theories. In Italy, as elsewhere in Europe, the concepts of humoral pathology were abandoned in the 18th century, when neurology was influenced by novel trends. Neurology acquired the status of clinical discipline (as "clinic of mental diseases") after national reunification (declared in 1861 but completed much later). At the end of the 19th and first decades of the 20th century, eminent Italian "neuropsychiatrists" (including, among many others, Ugo Cerletti, who introduced electroconvulsive shock therapy in 1938) stimulated novel knowledge and approaches, "centers of excellence" flourished, and "Neurological Institutes" were founded. In the first half of the 20th century, the history of Italian neurology was dominated by World Wars I and II (which stimulated studies on the wounded) and the fascist regime in-between the Wars (when the flow of information was instead very limited). Italy became a republic in 1946, and modern neurology and its distinction from psychiatry were finally promoted. The chapter also provides detailed accounts of scientific societies and journals dedicated to the neurological sciences in Italy.

  5. Chapter 15: Reliability of Wind Turbines

    Energy Technology Data Exchange (ETDEWEB)

    Sheng, Shuangwen; O' Connor, Ryan


    The global wind industry has witnessed exciting developments in recent years. The future will be even brighter with further reductions in capital and operation and maintenance costs, which can be accomplished with improved turbine reliability, especially when turbines are installed offshore. One opportunity for the industry to improve wind turbine reliability is through the exploration of reliability engineering life data analysis based on readily available data or maintenance records collected at typical wind plants. If adopted and conducted appropriately, these analyses can quickly save operation and maintenance costs in a potentially impactful manner. This chapter discusses wind turbine reliability by highlighting the methodology of reliability engineering life data analysis. It first briefly discusses fundamentals for wind turbine reliability and the current industry status. Then, the reliability engineering method for life analysis, including data collection, model development, and forecasting, is presented in detail and illustrated through two case studies. The chapter concludes with some remarks on potential opportunities to improve wind turbine reliability. An owner and operator's perspective is taken and mechanical components are used to exemplify the potential benefits of reliability engineering analysis to improve wind turbine reliability and availability.

  6. Map projections and the Internet: Chapter 4 (United States)

    Kessler, Fritz; Battersby, Sarah E.; Finn, Michael P.; Clarke, Keith


    The field of map projections can be described as mathematical, static, and challenging. However, this description is evolving in concert with the development of the Internet. The Internet has enabled new outlets for software applications, learning, and interaction with and about map projections . This chapter examines specific ways in which the Internet has moved map projections from a relatively obscure paper-based setting to a more engaging and accessible online environment. After a brief overview of map projections, this chapter discusses four perspectives on how map projections have been integrated into the Internet. First, map projections and their role in web maps and mapping services is examined. Second, an overview of online atlases and the map projections chosen for their maps is presented. Third, new programming languages and code libraries that enable map projections to be included in mapping applications are reviewed. Fourth, the Internet has facilitated map projection education and research especially with the map reader’s comprehension and understanding of complex topics like map projection distortion is discussed.

  7. Alcoholics anonymous and other twelve-step programs in recovery. (United States)

    Detar, D Todd


    Recovery is a new way of life for many patients; a life without substances to alter their moods but with a major change improving the physical, psychological, and emotional stability with improved overall health outcomes. The Twelve Steps of the Alcoholics Anonymous (AA) are the foundation of the AA, describing both the necessary actions and the spiritual basis for the recovery program of the AA. The Twelve Steps of the AA provide a structure for which a patient with alcoholism may turn for an answer to their problem of alcohol use, abuse, or dependence. Copyright © 2011 Elsevier Inc. All rights reserved.

  8. Beyond Chapter 4.7. (United States)

    Bandler, Lilon Gretl


    Chapter 4.7 of the National Statement on Ethical Conduct in Human Research refers specifically to Aboriginal and Torres Strait Islander Peoples. It lays out the points at which researchers working with Aboriginal and Torres Strait Islanders must consider their approach, and the engagement with individuals, communities or groups who are involved in or affected by their research. History, of Australia and of research involving Aboriginal and Torres Strait Islander Australians, has informed this approach. The response to that history has been a rational, institutionalised, systematic demand for a different perception of what should direct research and research processes to ensure engagement with and service to the community with whom the researchers wish to do the work. This paper considers whether these principles could inform the approach to other research work.

  9. Chapter 2: Stand-alone Applications - TOPCAT (United States)

    Miller, C. J.

    Tool for OPerations on Catalogues And Tables or TOPCAT is a graphical viewer for table data. It offers a variety of ways to work with data tables, including a browser for the cell data, viewers for information about table and column metadata, dataset visualization, and even analysis. We discuss a small subset of TOPCAT's functionalities in this chapter. TOPCAT was originally developed as part of the Starlink program in the United Kingdom. It is now maintained by AstroGrid. The program is written in pure Java and available under the GNU General Public License. It is available for download and a version is included in the software distribution accompanying this book. TOPCAT is a GUI interface on top of the STIL library. A command line interface to this library, STILTS, described in Chapter 21 provides scriptable access to many of the capabilities described here. The purpose of this tutorial is to provide an overview of TOPCAT to the novice user. The best place to look for and learn about TOPCAT is the web page maintained by Mark B. Taylor. There, TOPCAT documentation is provided in HTML, PDF, via screen shots, etc. In this chapter we take the user through a few examples that give the general idea of how TOPCAT works. The majority of the functionality of TOPCAT is not included in this short tutorial. Our goal in this tutorial is to lead the reader through an exercise that would result in a publication quality figure (e.g. for a journal article). Specifically, we will use TOPCAT to show how the color-magnitude relation of a galaxy cluster compares to that of all galaxies in the Sloan Digital Sky Survey (York et al. 2000). This diagnostic is used not only in cluster finding, but its linear fit can provide insight into the age and/or metallicity of the oldest galaxies in galaxy clusters (which are some of the oldest galaxies in the Universe). The data we need for this exercise are: 1) the entire spectroscopic galaxy catalog from the SDSS, with galaxy positions, galaxy

  10. The strong coupling regime of twelve flavors QCD

    NARCIS (Netherlands)

    Silva, Tiago Nunes da; Pallante, Elisabetta


    We summarize the results recently reported in Ref.[1] [A. Deuzeman, M.P. Lombardo, T. Nunes da Silva and E. Pallante,"The bulk transition of QCD with twelve flavors and the role of improvement"] for the SU(3) gauge theory with Nf=12 fundamental flavors, and we add some numerical evidence and theoret

  11. EFFORTS Technical annex for the twelve month progress report

    DEFF Research Database (Denmark)

    Andreasen, Jan Lasson; Eriksen, Morten; Thomas christensen, Thomas Vennick;

    The present report is documentation for the work carried out at DTU during the second year of project activity. The report describes the work completed by DTU in general as well as on the active sub-tasks within materials properties, friction modelling and physical modelling, over the last twelve...

  12. Bibliography of Spanish Materials for Students, Grades Seven through Twelve. (United States)

    California State Dept. of Education, Sacramento.

    This annotated bibliography of Spanish materials for students in grades seven through twelve is divided into the following categories: (1) Art, Drama, Music, and Poetry; (2) Books in Series; (3) Culture; (4) Dictionaries and Encyclopedias; (5) Literature; (6) Mathematics; (7) Physical Education, Health, and Recreation; (8) Reading and Language…

  13. Chapter 4: Geological Carbon Sequestration

    Energy Technology Data Exchange (ETDEWEB)

    Friedmann, J; Herzog, H


    Carbon sequestration is the long term isolation of carbon dioxide from the atmosphere through physical, chemical, biological, or engineered processes. The largest potential reservoirs for storing carbon are the deep oceans and geological reservoirs in the earth's upper crust. This chapter focuses on geological sequestration because it appears to be the most promising large-scale approach for the 2050 timeframe. It does not discuss ocean or terrestrial sequestration. In order to achieve substantial GHG reductions, geological storage needs to be deployed at a large scale. For example, 1 Gt C/yr (3.6 Gt CO{sub 2}/yr) abatement, requires carbon capture and storage (CCS) from 600 large pulverized coal plants ({approx}1000 MW each) or 3600 injection projects at the scale of Statoil's Sleipner project. At present, global carbon emissions from coal approximate 2.5 Gt C. However, given reasonable economic and demand growth projections in a business-as-usual context, global coal emissions could account for 9 Gt C. These volumes highlight the need to develop rapidly an understanding of typical crustal response to such large projects, and the magnitude of the effort prompts certain concerns regarding implementation, efficiency, and risk of the enterprise. The key questions of subsurface engineering and surface safety associated with carbon sequestration are: (1) Subsurface issues: (a) Is there enough capacity to store CO{sub 2} where needed? (b) Do we understand storage mechanisms well enough? (c) Could we establish a process to certify injection sites with our current level of understanding? (d) Once injected, can we monitor and verify the movement of subsurface CO{sub 2}? (2) Near surface issues: (a) How might the siting of new coal plants be influenced by the distribution of storage sites? (b) What is the probability of CO{sub 2} escaping from injection sites? What are the attendant risks? Can we detect leakage if it occurs? (3) Will surface leakage negate or


    Energy Technology Data Exchange (ETDEWEB)

    Ekechukwu, A


    The most common method of analysis for beryllium is inductively coupled plasma atomic emission spectrometry (ICP-AES). This method, along with inductively coupled plasma mass spectrometry (ICP-MS), is discussed in Chapter 6. However, other methods exist and have been used for different applications. These methods include spectroscopic, chromatographic, colorimetric, and electrochemical. This chapter provides an overview of beryllium analysis methods other than plasma spectrometry (inductively coupled plasma atomic emission spectrometry or mass spectrometry). The basic methods, detection limits and interferences are described. Specific applications from the literature are also presented.

  15. Chapter 8: Biomass Pyrolysis Oils

    Energy Technology Data Exchange (ETDEWEB)

    McCormick, Robert L.; Baldwin, Robert M.; Arbogast, Stephen; Bellman, Don; Paynter, Dave; Wykowski, Jim


    Fast pyrolysis is heating on the order of 1000 degrees C/s in the absence of oxygen to 40-600 degrees C, which causes decomposition of the biomass. Liquid product yield from biomass can be as much as 80% of starting dry weight and contains up to 75% of the biomass energy content. Other products are gases, primarily carbon monoxide, carbon dioxide, and methane, as well as solid char and ash. Residence time in the reactor is only 0.5-2 s so that relatively small, low-capital-cost reactors can be used. The low capital cost combined with greenhouse gas emission reductions relative to petroleum fuels of 50-95% makes pyrolysis an attractive process. The pyrolysis liquids have been investigated as a refinery feedstock and as stand-alone fuels. Utilization of raw pyrolysis oil has proven challenging. The organic fraction is highly corrosive because of its high organic acid content. High water content lowers the net heating value and can increase corrosivity. It can be poorly soluble in petroleum or petroleum products and can readily absorb water. Distillation residues can be as high as 50%, viscosity can be high, oils can exhibit poor stability in storage, and they can contain suspended solids. The ignition quality of raw pyrolysis oils is poor, with cetane number estimates ranging from 0 to 35, but more likely to be in the lower end of that range. While the use of raw pyrolysis oils in certain specific applications with specialized combustion equipment may be possible, raw oils must be significantly upgraded for use in on-highway spark-ignition (SI) and compression-ignition (CI) engines. Upgrading approaches most often involve catalytic hydrodeoxygenation, one of a class of reactions known as hydrotreating or hydroprocessing. This chapter discusses the properties of raw and upgraded pyrolysis oils, as well as the potential for integrating biomass pyrolysis with a petroleum refinery to significantly reduce the hydroprocessing cost.

  16. Volcanism on Mars. Chapter 41 (United States)

    Zimbelman, J. R.; Garry, W. B.; Bleacher, J. E.; Crown, D. A.


    Spacecraft exploration has revealed abundant evidence that Mars possesses some of the most dramatic volcanic landforms found anywhere within the solar system. How did a planet half the size of Earth produce volcanoes like Olympus Mons, which is several times the size of the largest volcanoes on Earth? This question is an example of the kinds of issues currently being investigated as part of the space-age scientific endeavor called "comparative planetology." This chapter summarizes the basic information currently known about volcanism on Mars. The volcanoes on Mars appear to be broadly similar in overall morphology (although, often quite different in scale) to volcanic features on Earth, which suggests that Martian eruptive processes are not significantly different from the volcanic styles and processes on Earth. Martian volcanoes are found on terrains of different age, and Martian volcanic rocks are estimated to comprise more than 50% of the Martian surface. This is in contrast to volcanism on smaller bodies such as Earth's Moon, where volcanic activity was mainly confined to the first half of lunar history (see "Volcanism on the Moon"). Comparative planetology supports the concept that volcanism is the primary mechanism for a planetary body to get rid of its internal heat; smaller bodies tend to lose their internal heat more rapidly than larger bodies (although, Jupiter's moon Io appears to contradict this trend; Io's intense volcanic activity is powered by unique gravitational tidal forces within the Jovian system; see "Volcanism on Io"), so that volcanic activity on Mars would be expected to differ considerably from that found on Earth and the Moon.

  17. Chapter 17: Estimating Net Savings: Common Practices

    Energy Technology Data Exchange (ETDEWEB)

    Violette, D. M.; Rathbun, P.


    This chapter focuses on the methods used to estimate net energy savings in evaluation, measurement, and verification (EM&V) studies for energy efficiency (EE) programs. The chapter provides a definition of net savings, which remains an unsettled topic both within the EE evaluation community and across the broader public policy evaluation community, particularly in the context of attribution of savings to particular program. The chapter differs from the measure-specific Uniform Methods Project (UMP) chapters in both its approach and work product. Unlike other UMP resources that provide recommended protocols for determining gross energy savings, this chapter describes and compares the current industry practices for determining net energy savings, but does not prescribe particular methods.

  18. Chapter 6: CPV Tracking and Trackers

    Energy Technology Data Exchange (ETDEWEB)

    Luque-Heredia, Ignacio; Magalhaes, Pedro; Muller, Matthew


    This chapter explains the functional requirements of a concentrator photovoltaic (CPV) sun tracker. It derives the design specifications of a CPV tracker. The chapter presents taxonomy of trackers describing the most common tracking architectures, based on the number of axes, their relative position, and the foundation and placing of tracking drives. It deals with the structural issues related to tracker design, mainly related to structural flexure and its impact on the system's acceptance angle. The chapter analyzes the auto-calibrated sun tracking control, by describing the state of the art and its development background. It explores the sun tracking accuracy measurement with a practical example. The chapter discusses tracker manufacturing and tracker field works. It reviews survey of different types of tracker designs obtained from different manufacturers. Finally, the chapter deals with IEC62817, the technical standard developed for CPV sun trackers.

  19. Twelve Theses on Reactive Rules for the Web


    Bry, François; Eckert, Michael


    Reactivity, the ability to detect and react to events, is an essential functionality in many information systems. In particular, Web systems such as online marketplaces, adaptive (e.g., recommender) sys- tems, and Web services, react to events such as Web page updates or data posted to a server. This article investigates issues of relevance in designing high-level programming languages dedicated to reactivity on the Web. It presents twelve theses on features desira...

  20. Premarital Sex in the Last Twelve Months and Its Predictors among Students of Wollega University, Ethiopia. (United States)

    Regassa, Tesfaye; Chala, Dereje; Adeba, Emiru


    Premarital sex increases the risk of unintended pregnancy and sexually transmitted infections including HIV if unprotected and contraception is not used. Thus, the objective of this study was to assess premarital sex in the last twelve months and its predictors among regular undergraduate students of Wollega University. A cross-sectional survey using pretested, structured questionnaire was conducted on a total of 704 regular undergraduate students of Wollega University from February to March, 2014. We used multistage sampling technique to recruit study participants. Binary and multivariable logistic regressions were performed using SPSS version 20 to assess predictors of premarital sex. Statistical significance was determined through a 95% confidence level. Wollega University youths who had premarital sex in the last twelve months were 28.4%; 55.5% of them did not use condom during last sex while 31.3% engaged in multiple sex. Being male [Adjusted Odds Ratio (AOR)(95% Confidence Interval(CI))=2.7(1.58-4.75)], age 20-24 years [AOR(95%CI)=2.8(1.13-7.20)], training on how to use condom [AOR(95%CI)=1.7(1.17-2.46)], being tested for HIV [AOR(95%CI)=2.3(1.48-3.53)], using social media frequently [AOR(95%CI)=1.8(1.14-2.88)], having comprehensive knowledge of HIV [AOR(95% CI)=1.5(1.01-2.10)], alcohol use [AOR (95%CI)=2.2(1.31-3.56)] were associated with increased odds of premarital sex in the last twelve months. Nearly one-third of regular undergraduate students of the university were engaged in premarital sex in the last twelve months. Being male, using social media frequently and alcohol use were associated with increased odds of premarital sex in the stated period. Thus, higher institutions have to deliver abstinence messages alongside information about self-protection.

  1. Numerical Prediction of Dust. Chapter 10 (United States)

    Benedetti, Angela; Baldasano, J. M.; Basart, S.; Benincasa, F.; Boucher, O.; Brooks, M.; Chen, J. P.; Colarco, P. R.; Gong, S.; Huneeus, N.; Jones, L; Lu, S.; Menut, L.; Mulcahy, J.; Nickovic, S.; Morcrette, J.-J.; Perez, C.; Reid, J. S.; Sekiyama, T. T.; Tanaka, T.; Terradellas, E.; Westphal, D. L.; Zhang, X.-Y.; Zhou, C.-H.


    Covers the whole breadth of mineral dust research, from a scientific perspective Presents interdisciplinary work including results from field campaigns, satellite observations, laboratory studies, computer modelling and theoretical studies Explores the role of dust as a player and recorder of environmental change This volume presents state-of-the-art research about mineral dust, including results from field campaigns, satellite observations, laboratory studies, computer modelling and theoretical studies. Dust research is a new, dynamic and fast-growing area of science and due to its multiple roles in the Earth system, dust has become a fascinating topic for many scientific disciplines. Aspects of dust research covered in this book reach from timescales of minutes (as with dust devils, cloud processes, and radiation) to millennia (as with loess formation and oceanic sediments), making dust both a player and recorder of environmental change. The book is structured in four main parts that explore characteristics of dust, the global dust cycle, impacts of dust on the Earth system, and dust as a climate indicator. The chapters in these parts provide a comprehensive, detailed overview of this highly interdisciplinary subject. The contributions presented here cover dust from source to sink and describe all the processes dust particles undergo while travelling through the atmosphere. Chapters explore how dust is lifted and transported, how it affects radiation, clouds, regional circulations, precipitation and chemical processes in the atmosphere, and how it deteriorates air quality. The book explores how dust is removed from the atmosphere by gravitational settling, turbulence or precipitation, how iron contained in dust fertilizes terrestrial and marine ecosystems, and about the role that dust plays in human health. We learn how dust is observed, simulated using computer models and forecast. The book also details the role of dust deposits for climate reconstructions

  2. The twelve theses: a call to a new reformation

    Directory of Open Access Journals (Sweden)

    John Shelby Spong


    Full Text Available With every discovery emerging from the world of science over the last 500 years concerning the origins of the universe and of life itself, the traditional explanations offered by the Christian Church appeared to be more and more dated and irrelevant.  Christian leaders, unable to embrace the knowledge revolution seemed to believe  that the only way to save Christianity was not to disturb the old patterns either by listening to, much less by entertaining the new knowledge. I tried to articulate this challenge in a book entitled: Why Christianity Must Change or Die, published in 1998.  In that book I examined in detail the issues that I was convinced Christianity must address. Shortly after that book was published I reduced its content to twelve theses, which I attached in Luther-like fashion to the great doors on the Chapel of Mansfield College at Oxford University in the United Kingdom. I then mailed copies of those Twelve Theses to every acknowledged Christian leader of the world. It was an attempt to call them into a debate on the real issues that I was certain the Christian Church now faced.  I framed my twelve theses in the boldest, most provocative language possible, designed primarily to elicit response and debate. I welcome responses from Christians everywhere.  I claim no expertise or certainty in developing answers, but I am quite confident that I do understand the problems we are facing as Christians who are seeking to relate to the 21st century.

  3. Where Social and Professional Networking Meet: The Virtual Association Chapter (United States)

    Noxon, Rose


    Online Capella University wanted to sponsor an International Society for Performance Improvement (ISPI) chapter. Using social networking platforms, a new type of chapter was designed. The virtual chapter breaks new ground on more than the chapter's platform; it is also the first university-sponsored chapter and has a unique approach to…

  4. How to write a medical book chapter? (United States)

    Kendirci, Muammer


    Invited medical book chapters are usually requested by editors from experienced authors who have made significant contributions to the literature in certain fields requested by an editor from an experienced. Before the start of the writing process a consensus should be established between the editor and the author with regard to the title, deadline, specific instructions and content of the manuscript. Certain issues concerning a chapter can be negotiated by the parties beforehand, but some issues cannot. As writing a medical book chapter is seen as an honor in its own right, the assignment needs to be treated with sincerity by elucidating the topic in detail, and maximal effort should be made to keep in mind that the chapter will reach a large target audience. The purpose of this review article is to provide guidance to residents and junior specialists in the field of urology to improve their writing skills.

  5. Chapter 8: Plasma operation and control (United States)

    Gribov, Y.; Humphreys, D.; Kajiwara, K.; Lazarus, E. A.; Lister, J. B.; Ozeki, T.; Portone, A.; Shimada, M.; Sips, A. C. C.; Wesley, J. C.


    The ITER plasma control system has the same functional scope as the control systems in present tokamaks. These are plasma operation scenario sequencing, plasma basic control (magnetic and kinetic), plasma advanced control (control of RWMs, NTMs, ELMs, error fields, etc) and plasma fast shutdown. This chapter considers only plasma initiation and plasma basic control. This chapter describes the progress achieved in these areas in the tokamak experiments since the ITER Physics Basis (1999 Nucl. Fusion 39 2577) was written and the results of assessment of ITER to provide the plasma initiation and basic control. This assessment was done for the present ITER design (15 MA machine) at a more detailed level than it was done for the ITER design 1998 (21 MA machine) described in the ITER Physics Basis (1999 Nucl. Fusion 39 2577). The experiments on plasma initiation performed in DIII-D and JT-60U, as well as the theoretical studies performed for ITER, have demonstrated that, within specified assumptions on the plasma confinement and the impurity influx, ITER can produce plasma initiation in a low toroidal electric field (0.3 V m-1), if it is assisted by about 2 MW of ECRF heating. The plasma basic control includes control of the plasma current, position and shape—the plasma magnetic control, as well as control of other plasma global parameters or their profiles—the plasma performance control. The magnetic control is based on more reliable and simpler models of the control objects than those available at present for the plasma kinetic control. Moreover the real time diagnostics used for the magnetic control in many cases are more precise than those used for the kinetic control. Because of these reasons, the plasma magnetic control was developed for modern tokamaks and assessed for ITER better than the kinetic control. However, significant progress has been achieved in the plasma performance control during the last few years. Although the physics basis of plasma operation

  6. Gaia DR1 documentation Chapter 6: Variability (United States)

    Eyer, L.; Rimoldini, L.; Guy, L.; Holl, B.; Clementini, G.; Cuypers, J.; Mowlavi, N.; Lecoeur-Taïbi, I.; De Ridder, J.; Charnas, J.; Nienartowicz, K.


    This chapter describes the photometric variability processing of the Gaia DR1 data. Coordination Unit 7 is responsible for the variability analysis of over a billion celestial sources. In particular the definition, design, development, validation and provision of a software package for the data processing of photometrically variable objects. Data Processing Centre Geneva (DPCG) responsibilities cover all issues related to the computational part of the CU7 analysis. These span: hardware provisioning, including selection, deployment and optimisation of suitable hardware, choosing and developing software architecture, defining data and scientific workflows as well as operational activities such as configuration management, data import, time series reconstruction, storage and processing handling, visualisation and data export. CU7/DPCG is also responsible for interaction with other DPCs and CUs, software and programming training for the CU7 members, scientific software quality control and management of software and data lifecycle. Details about the specific data treatment steps of the Gaia DR1 data products are found in Eyer et al. (2017) and are not repeated here. The variability content of the Gaia DR1 focusses on a subsample of Cepheids and RR Lyrae stars around the South ecliptic pole, showcasing the performance of the Gaia photometry with respect to variable objects.

  7. Microscopic functional anatomy: Integumentary system: Chapter 17 (United States)

    Elliott, Diane G.; Ostrander, Gary K.


    Many of the features of the fish integument can only be observed microscopically. Because there are over 20,000 living fishes, mostly higher bony fishes (teleosts), a great diversity exists in the microscopic anatomy of the integument. This chapter presents several examples from varied taxonomic groups to illustrate the variation in morphological features. As in all vertebrate epidermis, the fundamental structural unit is the epithelial cell. This is the only constant feature, as a great diversity of cell types exists in the various fish taxa. Some of these include apocrine mucous cells and a variety of other secretory cells, ionocytes, sensory cells, and wandering cells such as leukocytes. The dermis consists essentially of two sets of collagen fibers arranged in opposing geodesic spirals around the body. The dermis of most fishes is divided into two major layers. The upper (outer) layer, the stratum spongiosum or stratum laxum, is a loose network of connective tissue, whereas the lower layer, the stratum compactum, is a dense layer consisting primarily of orthogonal collagen bands. There are also specialized dermal elements such as chromatophores scales, and fin rays.

  8. New Eyes on the Universe Twelve Cosmic Mysteries and the Tools We Need to Solve Them

    CERN Document Server

    Webb, Stephen


    "New Eyes on the Universe -- Twelve Cosmic Mysteries and the Tools We Need to Solve Them" gives an up-to-date broad overview of some of the key issues in modern astronomy and cosmology. It describes the vast amount of observational data that the new generation of observatories and telescopes are currently producing, and how that data might solve some of the outstanding puzzles inherent in our emerging world view. Included are questions such as: What is causing the Universe to blow itself apart? What could be powering the luminous gamma-ray bursters? Where is all the matter in the Uni


    Institute of Scientific and Technical Information of China (English)


    Direct chromosome analysis and FISH were performed on twelve primary gastric carcinomas. Two of them had simple chromosome changes: 48,XX, +8, +20, and 49, XY, +2, +8, +9, and the others had complicated chromosome changes, which includes much more numerical and structural chromosome aberrations. Frequent structural changes in the complicated types involved chromosome 7, 3, 1, 5 and 12 etc. The del 7q was noted in eight cases. The del (3p) and del (1p) were noted in six and five cases, respectively. The results provide some important clues for isolation of the genes related to gastric cancer.


    Sharma, P.V.


    This translation of Haramekhala – tantra of the author is based on Banaras Hindu University manuscript which seems to be a novel one. The manuscript runs into 133 stanzas in all in the form of dialogue between lord Siva and goddess Parvati. This is only the first chapter (of the great work) dealing with medicine. From stanza 109 onwards some magic spells are described and as such those have not been included in this translation. PMID:22557515



    Sharma, P. V.


    This translation of Haramekhala – tantra of the author is based on Banaras Hindu University manuscript which seems to be a novel one. The manuscript runs into 133 stanzas in all in the form of dialogue between lord Siva and goddess Parvati. This is only the first chapter (of the great work) dealing with medicine. From stanza 109 onwards some magic spells are described and as such those have not been included in this translation.

  12. Chapter 52: How to Build a Simple SIAP service (United States)

    Kent, B. R.

    This chapter will give an example of how to build a service around an archive of images using the Simple Image Access Protocol (SIAP). The different image service types and basic requirements for user input using a HTTP GET request will be described. The metadata requirements will be discussed. The service will return a VOTable and options for several different image formats, including FITS and JPEG.

  13. Chapter 17: Residential Behavior Protocol

    Energy Technology Data Exchange (ETDEWEB)

    Stewart, James [Cadmus Group, Waltham, MA (United States); Todd, Annika [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)


    Residential behavior-based (BB) programs use strategies grounded in the behavioral social sciences to influence household energy use. Strategies may include providing households with real-time or delayed feedback about their energy use; supplying energy-efficiency education and tips; rewarding households for reducing their energy use; comparing households to their peers; and establishing games, tournaments, and competitions. BB programs often target multiple energy end uses and encourage energy savings, demand savings, or both. Savings from BB programs are usually a small percentage of energy use, typically less than 5%.

  14. Chapter 16: Retrocommissioning Evaluation Protocol

    Energy Technology Data Exchange (ETDEWEB)

    Tiessen, A.


    Retrocommissioning (RCx) is a systematic process for optimizing energy performance in existing buildings. It specifically focuses on improving the control of energy-using equipment (e.g., heating, ventilation, and air conditioning equipment and lighting) and typically does not involve equipment replacement. Field results have shown proper RCx can achieve energy savings ranging from 5% to 20%, with a typical payback of 2 years or less. A study conducted on behalf of Lawrence Berkeley National Laboratory analyzed data from 11 utilities operating RCx programs across the United States. The dataset included 122 RCx projects and more than 950 RCx measures.

  15. Summary and findings: Chapter A (United States)

    Maslia, Morris L.; Suárez-Soto, René J.; Sautner, Jason B.; Anderson, Barbara A.; Jones, Elliott; Faye, Robert E.; Aral, Mustafa M.; Guan, Jiabao; Jang, Wonyong; Telci, Ilker T.; Grayman, Walter M.; Bove, Frank J.; Ruckart, Perri Z.; Moore, Susan M.


    The Agency for Toxic Substances and Disease Registry (ATSDR) is conducting epidemiological studies to evaluate the potential for health effects from exposures to volatile organic compounds (VOCs) in finished water supplied to family housing units at U.S. Marine Corps Base Camp Lejeune, North Carolina (USMCB Camp Lejeune). The core period of interest for the epidemiological studies is 1968– 1985. VOCs of major interest to the epidemiological studies include tetrachloroethylene (PCE), trichloroethylene (TCE), trans-1,2-dichloroethylene (1,2-tDCE), vinyl chloride (VC), and benzene.

  16. Study area description: Chapter 1 (United States)

    Rowland, Mary M.; Leu, Matthias; Hanser, Steven E.; Leu, Matthias; Knick, Steven T.; Aldridge, Cameron L.


    The boundary for the Wyoming Basins Ecoregional Assessment (WBEA) was largely determined by the co-occurrence of some of the largest tracts of intact sagebrush (Artemisia spp.) remaining in the western United States with areas of increasing resource extraction. The WBEA area includes two ecoregions in their entirety, Wyoming Basins and Utah-Wyoming Rocky Mountains, and portions of two others (Southern Rocky Mountains and Middle Rockies-Blue Mountains). Over half the study area is in Wyoming; the remainder includes parts of Colorado, Utah, Idaho, and Montana. Private landowners manage most (33.1%) of the land base in the WBEA, followed by the U.S. Forest Service (27.3%) and U.S. Bureau of Land Management (25.6%). Sagebrush is the dominant land cover type in the study area, totaling >130,000 km2 ; nearly half the sagebrush in the WBEA is managed by the U.S. Bureau of Land Management. Sagebrush in the WBEA faces many potential threats that also influence the broader sagebrush ecosystem. Climate change, drought, land-use practices (e.g., livestock grazing, oil and gas development), and human development have eliminated and fragmented the sagebrush ecosystem, altered fire regimes, and accelerated the invasion of exotic plants such as cheatgrass (Bromus tectorum). Less than 2% of sagebrush in the WBEA is permanently protected from land cover conversion.

  17. Chapter 21: Programmatic Interfaces - STILTS (United States)

    Fitzpatrick, M. J.

    STILTS is the Starlink Tables Infrastructure Library Tool Set developed by Mark Taylor of the former Starlink Project. STILTS is a command-line tool (see the NVOSS_HOME/bin/stilts command) providing access to the same functionality driving the TOPCAT application and can be run using either the STILTS-specific jar file, or the more general TOPCAT jar file (both are available in the NVOSS_HOME/java/lib directory and are included in the default software environment classpath). The heart of both STILTS and TOPCAT is the STIL Java library. STIL is designed to efficiently handle the input, output and processing of very large tabular datasets and the STILTS task interface makes it an ideal tool for the scripting environment. Multiple formats are supported (including FITS Binary Tables, VOTable, CSV, SQL databases and ASCII, amongst others) and while some tools will generically handle all supported formats, others are specific to the VOTable format. Converting a VOTable to a more script-friendly format is the first thing most users will encounter, but there are many other useful tools as well.

  18. Twelve tips for teaching medical students with dyslexia. (United States)

    Shaw, Sebastian Charles Keith; Anderson, John Leeds


    Dyslexia is a common learning difficulty. As a result of SS' own experiences as a medical student with dyslexia, we have been researching and teaching on this topic for the past two years. Here, we present twelve tips for teaching medical students with dyslexia. These are gathered from our personal experiences and research, discussions with other educators, and wider literature on the topic. This article aims to shed some light on dyslexia, and also to make practical suggestions. Teaching students with dyslexia should not be a daunting experience. Small changes to existing methods, at minor effort, can make a difference - for example, adding pastel colors to slide backgrounds or avoiding Serif fonts. These tips can help educators gain more insight into dyslexia and incorporate small, beneficial adaptations into their teaching.

  19. Antibacterial activities of extracts from twelve Centaurea species from Turkey

    Directory of Open Access Journals (Sweden)

    Tekeli Yener


    Full Text Available Members of the genus Centaurea (Asteraceae have been used in traditional plant-based medicine. The methanol extracts of twelve Centaurea species, of which five are endemic to Turkey flora, were screened for antibacterial activity against four bacteria (Escherichia coli, Bacillus cereus, Salmonella enteritidis, Staphylococcus aureus. The antibacterial activity was evaluated by the microdilution method and the minimum inhibition concentrations (MIC of the extracts were determined. C. cariensis subsp. microlepis exhibited an antimicrobial effect on all tested microorganisms. The extracts from eight Centaurea species (C. balsamita, C. calolepis, C. cariensis subsp. maculiceps, C. cariensis subsp. microlepis, C. kotschyi var. kotschyi, C. solstitialis subsp. solstitialis, C. urvillei subsp. urvillei and C. virgata possessed antibacterial activity against several of the tested microorganisms.

  20. Twelve tips on how to compile a medical educator's portfolio. (United States)

    Dalton, Claudia Lucy; Wilson, Anthony; Agius, Steven


    Medical education is an expanding area of specialist interest for medical professionals. Whilst most doctors will be familiar with the compilation of clinical portfolios for scrutiny of their clinical practice and provision of public accountability, teaching portfolios used specifically to gather and demonstrate medical education activity remain uncommon in many non-academic settings. For aspiring and early career medical educators in particular, their value should not be underestimated. Such a medical educator's portfolio (MEP) is a unique compendium of evidence that is invaluable for appraisal, revalidation, and promotion. It can stimulate and provide direction for professional development, and is a rich source for personal reflection and learning. We recommend that all new and aspiring medical educators prepare an MEP, and suggest twelve tips on how to skillfully compile one.

  1. Chapter 14: Chiller Evaluation Protocol

    Energy Technology Data Exchange (ETDEWEB)

    Tiessen, A.


    This protocol defines a chiller measure as a project that directly impacts equipment within the boundary of a chiller plant. A chiller plant encompasses a chiller--or multiple chillers--and associated auxiliary equipment. This protocol primarily covers electric-driven chillers and chiller plants. It does not include thermal energy storage and absorption chillers fired by natural gas or steam, although a similar methodology may be applicable to these chilled water system components. Chillers provide mechanical cooling for commercial, institutional, multiunit residential, and industrial facilities. Cooling may be required for facility heating, ventilation, and air conditioning systems or for process cooling loads (e.g., data centers, manufacturing process cooling). The vapor compression cycle, or refrigeration cycle, cools water in the chilled water loop by absorbing heat and rejecting it to either a condensing water loop (water cooled chillers) or to the ambient air (air-cooled chillers).

  2. Chapter 10: CPV Multijunction Solar Cell Characterization

    Energy Technology Data Exchange (ETDEWEB)

    Osterwald, Carl R.; Siefer, Gerald


    Characterization of solar cells can be divided into two types: the first is measurement of electrooptical semiconductor device parameters, and the second is determination of electrical conversion efficiency. This chapter reviews the multijunction concepts that are necessary for understanding Concentrator photovoltaic (CPV) cell characterization techniques, and describes how CPV efficiency is defined and used. For any I-V measurement of a multijunction cell, the sun simulator spectrum has to be adjusted in a way that all junctions generate the same photocurrent ratios with respect to each other as under reference conditions. The chapter discusses several procedures for spectral irradiance adjustments of solar simulators, essential for multijunction measurements. It overviews the light sources and optics commonly used in simulators for CPV cells under concentration. Finally, the chapter talks about the cell area, quantum efficiency (QE), and current-voltage (I-V) curve measurements that are needed to characterize cells as a function of irradiance.

  3. Planning and setting objectives in field studies: Chapter 2 (United States)

    Fisher, Robert N.; Dodd, C. Kenneth


    This chapter enumerates the steps required in designing and planning field studies on the ecology and conservation of reptiles, as these involve a high level of uncertainty and risk. To this end, the chapter differentiates between goals (descriptions of what one intends to accomplish) and objectives (the measurable steps required to achieve the established goals). Thus, meeting a specific goal may require many objectives. It may not be possible to define some of them until certain experiments have been conducted; often evaluations of sampling protocols are needed to increase certainty in the biological results. And if sampling locations are fixed and sampling events are repeated over time, then both study-specific covariates and sampling-specific covariates should exist. Additionally, other critical design considerations for field study include obtaining permits, as well as researching ethics and biosecurity issues.

  4. Examples of storm impacts on barrier islands: Chapter 4 (United States)

    Plant, Nathaniel G.; Doran, Kara; Stockdon, Hilary F.


    This chapter focuses on the morphologic variability of barrier islands and on the differences in storm response. It describes different types of barrier island response to individual storms, as well as the integrated response of barrier islands to many storms. The chapter considers case study on the Chandeleur Island chain, where a decadal time series of island elevation measurements have documented a wide range of barrier island responses to storms and long-term processes that are representative of barrier island behaviour at many other locations. These islands are low elevation, extremely vulnerable to storms and exhibit a diversity of storm responses. Additionally, this location experiences a moderately high rate of relative sea-level rise, increasing its vulnerability to the combined impacts of storms and long-term erosional processes. Understanding how natural processes, including storm impacts and intervening recovery periods interact with man-made restoration processes is also broadly relevant to understand the natural and human response to future storms.

  5. Snow and ice: Chapter 3 (United States)

    Littell, Jeremy; McAfee, Stephanie A.; O'Neel, Shad; Sass, Louis; Burgess, Evan; Colt, Steve; Clark, Paul; Hayward, Gregory D.; Colt, Steve; McTeague, Monica L.; Hollingsworth, Teresa N.


    glaciers surveyed within the Chugach have lost mass (with one exception), including glaciers that have advancing termini (Larsen et al. 2015).Glaciers that are not calving into the ocean are typically thinning by 3 m/year at their termini (Larsen et al. 2015).In the future, glaciers not calving into the ocean will retreat and shrink at rates equivalent to or higher than current rates of ice loss (Larsen et al. 2015).Columbia Glacier will likely retreat another 15 km and break into multiple tributaries over the next 20 years before stabilizing.Other tidewater glaciers have uncertain futures, but likely will not advance significantly in coming decades.These impacts will likely affect recreation and tourism through changes in reliable snowpack and access to recreation and viewsheds.

  6. Chapter 7: Primary standardization in radionuclide metrology

    Energy Technology Data Exchange (ETDEWEB)

    Delgado, Jose Ubiratan


    The chapter 7 presents: Primary methods for radionuclide standardization; 4πβ-γ Coincidence counting method; Anticoincidence; Counting π Method; Defined Solid Angle Counting Method; Liquid scintillator counting method (CIEMAT/NIST); Sum-peak Method and LNMRI Absolute Standardization.

  7. Workplace innovation in the Netherlands: chapter 8

    NARCIS (Netherlands)

    Pot, F.; Dhondt, S.; Korte, E. de; Oeij, P.; Vaas, F.


    Social innovation of work and employment is a prerequisite to achieve the EU2020 objectives of smart, sustainable and inclusive growth. It covers labor market innovation on societal level and workplace innovation on organizational level. This chapter focuses on the latter. Workplace innovations are

  8. Denmark - Chapter in Handbook of Global Bioethics

    DEFF Research Database (Denmark)

    Nielsen, Linda; Faber, Berit A.


    This chapter about bioethics in Denmark focuses on specific Danish characteristics. These are the early start of a bioethics debate, legislation and bioethics councils; the independence of the councils and the parliamentarians voting on ethical issues; the introduction and extraordinary importanc...

  9. Chapter 6: Accidents; Capitulo 6: Acidentes

    Energy Technology Data Exchange (ETDEWEB)



    The chapter 6 talks about the accidents with radiators all over the world, specifically, the Stimos, in Italy, 1975, San Salvador, in El Salvador, 1989, Soreq, in Israel, 1990, Nesvizh, in Byelorussian, 1991, in Illinois, US, 1965, in Maryland, US, 1991, Hanoi, Vietnam, 1992, Fleurus, in Belgium, 2006. Comments on the accidents and mainly the learned lessons.

  10. Workplace innovation in the Netherlands: chapter 8

    NARCIS (Netherlands)

    Pot, F.; Dhondt, S.; Korte, E. de; Oeij, P.; Vaas, F.


    Social innovation of work and employment is a prerequisite to achieve the EU2020 objectives of smart, sustainable and inclusive growth. It covers labor market innovation on societal level and workplace innovation on organizational level. This chapter focuses on the latter. Workplace innovations are

  11. Science, practice, and place [Chapter 2 (United States)

    Daniel R. Williams


    Place-oriented inquiry and practice are proposed as keys to overcoming the persistent gap between science and practice. This chapter begins by describing some of the reasons science fails to simplify conservation practice, highlighting the challenges associated with the social and ecological sciences of multi-scaled complexity. Place concepts help scientists and...

  12. Transfer of property inter vivos : chapter 7

    NARCIS (Netherlands)

    van Vliet, Lars


    This chapter will give an overview of the various transfer systems for movable property and immovable property. It will focus on voluntary transfers based on a legal act between the transferor and transferee. First the difference between the unitary approach and the functional approach to passing of

  13. Twelve tips for designing and running longitudinal integrated clerkships. (United States)

    Ellaway, Rachel; Graves, Lisa; Berry, Sue; Myhre, Doug; Cummings, Beth-Ann; Konkin, Jill


    Longitudinal integrated clerkships (LICs) involve learners spending an extended time in a clinical setting (or a variety of interlinked clinical settings) where their clinical learning opportunities are interwoven through continuities of patient contact and care, continuities of assessment and supervision, and continuities of clinical and cultural learning. Our twelve tips are grounded in the lived experiences of designing, implementing, maintaining, and evaluating LICs, and in the extant literature on LICs. We consider: general issues (anticipated benefits and challenges associated with starting and running an LIC); logistical issues (how long each longitudinal experience should last, where it will take place, the number of learners who can be accommodated); and integration issues (how the LIC interfaces with the rest of the program, and the need for evaluation that aligns with the dynamics of the LIC model). Although this paper is primarily aimed at those who are considering setting up an LIC in their own institutions or who are already running an LIC we also offer our recommendations as a reflection on the broader dynamics of medical education and on the priorities and issues we all face in designing and running educational programs.

  14. Commercializing Government-sponsored Innovations: Twelve Successful Buildings Case Studies (United States)

    Brown, M. A.; Berry, L. G.; Goel, R. K.


    This report examines the commercialization and use of R and D results funded by DOE's Office of Buildings and Community Systems (OBCS), an office that is dedicated to improving the energy efficiency of the nation's buildings. Three goals guided the research described in this report: to improve understanding of the factors that hinder or facilitate the transfer of OBCS R and D results, to determine which technology transfer strategies are most effective and under what circumstances each is appropriate, and to document the market penetration and energy savings achieved by successfully-commercialized innovations that have received OBCS support. Twelve successfully-commercialized innovations are discussed here. The methodology employed involved a review of the literature, interviews with innovation program managers and industry personnel, and data collection from secondary sources. Six generic technology transfer strategies are also described. Of these, contracting R and D to industrial partners is found to be the most commonly used strategy in our case studies. The market penetration achieved to date by the innovations studied ranges from less than 1% to 100%. For the three innovations with the highest predicted levels of energy savings (i.e., the flame retention head oil burner, low-E windows, and solid-state ballasts), combined cumulative savings by the year 2000 are likely to approach 2 quads. To date the energy savings for these three innovations have been about 0.2 quads. Our case studies illustrate the important role federal agencies can play in commercializing new technologies.

  15. The strong coupling regime of twelve flavors QCD

    CERN Document Server

    da Silva, Tiago Nunes


    We summarize the results recently reported in Ref.[1] [A. Deuzeman, M.P. Lombardo, T. Nunes da Silva and E. Pallante,"The bulk transition of QCD with twelve flavors and the role of improvement"] for the SU(3) gauge theory with Nf=12 fundamental flavors, and we add some numerical evidence and theoretical discussion. In particular, we study the nature of the bulk transition that separates a chirally broken phase at strong coupling from a chirally restored phase at weak coupling. When a non-improved action is used, a rapid crossover is observed at small bare quark masses. Our results confirm a first order nature for this transition, in agreement with previous results we obtained using an improved action. As shown in Ref.[1], when improvement of the action is used, the transition is preceded by a second rapid crossover at weaker coupling and an exotic phase emerges, where chiral symmetry is not yet broken. This can be explained [1] by the non hermiticity of the improved lattice Transfer matrix, arising from the c...

  16. Twelve Years of Education and Public Outreach with the Fermi Gamma-ray Space Telescope

    CERN Document Server

    Cominsky, Lynn; Simonnet, Aurore; Education, the Fermi


    During the past twelve years, NASA's Fermi Gamma-ray Space Telescope has supported a wide range of Education and Public Outreach (E/PO) activities, targeting K-14 students and the general public. The purpose of the Fermi E/PO program is to increase student and public understanding of the science of the high-energy Universe, through inspiring, engaging and educational activities linked to the mission's science objectives. The E/PO program has additional more general goals, including increasing the diversity of students in the Science, Technology, Engineering and Mathematics (STEM) pipeline, and increasing public awareness and understanding of Fermi science and technology. Fermi's multi-faceted E/PO program includes elements in each major outcome category: Higher Education; Elementary and Secondary Education; Informal Education and Public Outreach.

  17. Seville City Hall Chapter Room ceiling decoration

    Directory of Open Access Journals (Sweden)

    Robador, M. D.


    Full Text Available The present article describes a chemical and physical study of the colour, chemical composition and mineral phases of the decorative materials in the Seville City Hall Chapter House ceiling. The findings showed that the inner most layer of material, calcite, was covered with white lead, in turn concealed under a layer of gilded bole. The ceiling underwent re-gilding, also over bole, due in all likelihood to wear on the original gold leaf. In the nineteenth century, the entire ceiling with the exception of the inscriptions was whitewashed with calcite and white lead. Silver was employed on King John I’s sword (coffer 27. Gold leaf was used to adorn the royal attributes: crowns, belts, sceptres, swords and rosary beads. The high reliefs were likewise gilded. The pigments identified on the ceiling adornments included azurite, malachite, vermilion and gas black. A lime and ground dolomite mortar was used throughout.

    El objetivo de este trabajo es el estudio de diferentes aspectos, como el color, la composición química y las fases mineralógicas presentes en los diferentes materiales que forman la ornamentación del techo de la Sala Capitular del Ayuntamiento de Sevilla, mediante métodos físicos y químicos. Nuestros resultados muestran que el dorado fue realizado sobre una capa de bol previamente depositada sobre una lámina de blanco de plomo que cubría un estrato de calcita. Posteriormente, y probablemente debido a alteraciones en el dorado original, el techo fue de nuevo dorado usando una técnica similar. En el siglo XIX, casi todo el techo, excepto las zonas con inscripciones, fue blanqueado usando una mezcla de calcita y blanco de plomo. Se empleó plata para cubrir la espada del rey Juan I (casetón 27. Finísimas láminas de oro se usaron para decorar los atributos reales: coronas, cinturones, cetros, espadas y rosarios. En diferentes partes de la decoración fueron detectados pigmentos como azurita, malaquita, bermellón y

  18. The Synthesis and Antitumor Activity of Twelve Galloyl Glucosides

    Directory of Open Access Journals (Sweden)

    Chang-Wei Li


    Full Text Available Twelve galloyl glucosides 1–12, showing diverse substitution patterns with two or three galloyl groups, were synthesized using commercially available, low-cost D-glucose and gallic acid as starting materials. Among them, three compounds, methyl 3,6-di-O-galloyl-α-D-glucopyranoside (9, ethyl 2,3-di-O-galloyl-α-D-glucopyranoside (11 and ethyl 2,3-di-O-galloyl-β-D-glucopyranoside (12, are new compounds and other six, 1,6-di-O-galloyl-β-D-glucopyranose (1, 1,4,6-tri-O-galloyl-β-D-glucopyranose (2, 1,2-di-O-galloyl-β-D-glucopyranose (3, 1,3-di-O-galloyl-β-D-glucopyranose (4, 1,2,3-tri-O-galloyl-α-D-glucopyranose (6 and methyl 3,4,6-tri-O-galloyl-α-D-glucopyranoside (10, were synthesized for the first time in the present study. In in vitro MTT assay, 1–12 inhibited human cancer K562, HL-60 and HeLa cells with inhibition rates ranging from 64.2% to 92.9% at 100 μg/mL, and their IC50 values were determined to be varied in 17.2–124.7 μM on the tested three human cancer cell lines. In addition, compounds 1–12 inhibited murine sarcoma S180 cells with inhibition rates ranging from 38.7% to 52.8% at 100 μg/mL in the in vitro MTT assay, and in vivo antitumor activity of 1 and 2 was also detected in murine sarcoma S180 tumor-bearing Kunming mice using taxol as positive control.

  19. [Twelve years of working of Brazzaville cancer registry]. (United States)

    Nsondé Malanda, Judith; Nkoua Mbon, Jean Bernard; Bambara, Augustin Tozoula; Ibara, Gérard; Minga, Benoît; Nkoua Epala, Brice; Gombé Mbalawa, Charles


    The Brazzaville cancer registry was created in 1996 with the support of the International Agency Research against Cancer (IARC) which is located in Lyon, France. The Brazzaville cancer registry is a registry which is based on population which records new cancer cases occurring in Brazzaville by using Canreg 4.0 Software. Its aim is to supply useful information to fight against cancer to physicians and to decision makers. We conducted this study whose target was to determine the incidence of cancer in Brazzaville during twelve years, from January 1st, 1998 to December 31, 2009. During that period 6,048 new cancer cases were recorded: 3,377 women (55.8%), 2,384 men (39.4%), and 287 children (4.8%) from 0 to 14 years old with an annual average of 504 cases. Middle age to the patient's diagnosis was 49.5 years in female sex and 505.5 years old for male sex. The incidence rate of cancers in Brazzaville was 39.8 or 100.000 inhabitants per year and by sex we observed 49 to female sex and 35.2 for male sex. The first cancers localizations observed to women were in order of frequency: breast, cervix uterine, liver ovaries, hematopoietic system, to men : liver, prostate, hematopoietic system, colon and stomach; to children : retina, kidney, hematopoietic system, liver and bones. These rates are the basis to know the burden of cancer among all pathologies of Brazzaville and the achievement of a national cancer control program.

  20. Hyperinsulinism and hyperammonemia syndrome: report of twelve unrelated patients. (United States)

    De Lonlay, P; Benelli, C; Fouque, F; Ganguly, A; Aral, B; Dionisi-Vici, C; Touati, G; Heinrichs, C; Rabier, D; Kamoun, P; Robert, J J; Stanley, C; Saudubray, J M


    Hyperinsulinism and hyperammonemia syndrome has been reported as a cause of moderately severe hyperinsulinism with diffuse involvement of the pancreas. The disorder is caused by gain of function mutations in the GLUD1 gene, resulting in a decreased inhibitory effect of guanosine triphosphate on the glutamate dehydrogenase (GDH) enzyme. Twelve unrelated patients (six males, six females) with hyperinsulinism and hyperammonemia syndrome have been investigated. The phenotypes were clinically heterogeneous, with neonatal and infancy-onset hypoglycemia and variable responsiveness to medical (diazoxide) and dietary (leucine-restricted diet) treatment. Hyperammonemia (90-200 micromol/L, normal carbamylglutamate administration. The patients had mean basal GDH activity (18.3 +/- 0.9 nmol/min/mg protein) not different from controls (17.9 +/- 1.8 nmol/min/mg protein) in cultured lymphoblasts. The sensitivity of GDH activity to inhibition by guanosine triphosphate was reduced in all patient lymphoblast cultures (IC(50), or concentrations required for 50% inhibition of GDH activity, ranging from 140 to 580 nM, compared with control IC(50) value of 83 +/- 1.0 nmol/L). The allosteric effect of ADP was within the normal range. The activating effect of leucine on GDH activity varied among the patients, with a significant decrease of sensitivity that was correlated with the negative clinical response to a leucine-restricted diet in plasma glucose levels in four patients. Molecular studies were performed in 11 patients. Heterozygous mutations were localized in the antenna region (four patients in exon 11, two patients in exon 12) as well as in the guanosine triphosphate binding site (two patients in exon 6, two patients in exon 7) of the GLUD1 gene. No mutation has been found in one patient after sequencing the exons 5-13 of the gene.

  1. Commercializing government-sponsored innovations: Twelve successful buildings case studies

    Energy Technology Data Exchange (ETDEWEB)

    Brown, M.A.; Berry, L.G.; Goel, R.K.


    This report examines the commercialization and use of R and D results funded by DOE's Office of Buildings and Community Systems (OBCS), an office that is dedicated to improving the energy efficiency of the nation's buildings. Three goals guided the research described in this report: to improve understanding of the factors that hinder or facilitate the transfer of OBCS R and D results, to determine which technology transfer strategies are most effective and under what circumstances each is appropriate, and to document the market penetration and energy savings achieved by successfully-commercialized innovations that have received OBCS support. Twelve successfully-commercialized innovations are discussed here. The methodology employed involved a review of the literature, interviews with innovation program managers and industry personnel, and data collection from secondary sources. Six generic technology transfer strategies are also described. Of these, contracting R and D to industrial partners is found to be the most commonly used strategy in our case studies. The market penetration achieved to date by the innovations studied ranges from less than 1% to 100%. For the three innovations with the highest predicted levels of energy savings (i.e., the flame retention head oil burner, low-E windows, and solid-state ballasts), combined cumulative savings by the year 2000 are likely to approach 2 quads. To date the energy savings for these three innovations have been about 0.2 quads. Our case studies illustrate the important role federal agencies can play in commercializing new technologies. 27 refs., 21 figs., 4 tabs.

  2. Chapter 2. The market orientation concept


    Lambin, Jean-Jacques


    The objective of this chapter is to introduce the concept of market orientation presented as an alternative to the traditional marketing concept. The Internet technology is creating a dual trading arena where traditional market actors have changing roles and new actors are emerging. To cope with this increased market complexity, a distinction is made between a cultural and an instrumental definition of the Market Orientation (MO) concept. Market orientation as an organisational culture is a c...

  3. Development and characterization of twelve microsatellite markers for Porphyra linearis Greville. (United States)

    Varela-Álvarez, Elena; Paulino, Cristina; Serrão, Ester A


    The genus Porphyra (and its sister genus Pyropia) contains important red algal species that are cultivated and/or harvested for human consumption, sustaining a billion-dollar aquaculture industry. A vast amount of research has been focused on species of this genus, including studies on genetics and genomics among other areas. Twelve novel microsatellite markers were developed here for Porphyra linearis. Markers were characterized using 32 individuals collected from four natural populations of P. linearis with total heterozygosity varying from 0.098 to 0.916. The number of alleles per locus ranged from 2 to 18. All markers showed cross amplification with Porphyra umbilicalis and/or Porphyra dioica. These polymorphic microsatellite markers are useful for investigating population genetic diversity and differentiation in P. linearis and may become useful for other genetic research on the reproductive biology of this important species.

  4. Twelve tips for developing and delivering a massive open online course in medical education. (United States)

    Pickering, James D; Henningsohn, Lars; DeRuiter, Marco C; de Jong, Peter G M; Reinders, Marlies E J


    Massive open online courses (MOOCs) are a novel mode of online learning. They are typically based on higher education courses and can attract a high number of learners, often in the thousands. They are distinct from on-campus education and deliver the learning objectives through a series of short videos, recommended readings and discussion fora, alongside automated assessments. Within medical education the role of MOOCs remains unclear, with recent proposals including continuing professional development, interprofessional education or integration into campus-based blended learning curricula. In this twelve tips article, we aim to provide a framework for readers to use when developing, delivering and evaluating a MOOC within medical education based on the literature and our own experience. Practical advice is provided on how to design the appropriate curriculum, engage with learners on the platform, select suitable assessments, and comprehensively evaluate the impact of your course.

  5. Hepatoprotective activity of twelve novel 7'-hydroxy lignan glucosides from Arctii Fructus. (United States)

    Yang, Ya-Nan; Huang, Xiao-Ying; Feng, Zi-Ming; Jiang, Jian-Shuang; Zhang, Pei-Cheng


    Twelve novel 7'-hydroxy lignan glucosides (1-12), including two benzofuran-type neolignans, two 8-O-4' neolignans, two dibenzylbutyrolactone lignans, and six tetrahydrofuranoid lignans, together with six known lignan glucosides (13-18), were isolated from the fruit of Arctium lappa L. (Asteraceae), commonly known as Arctii Fructus. Their structures were elucidated using spectroscopy (1D and 2D NMR, MS, IR, ORD, and UV) and on the basis of chemical evidence. The absolute configurations of compounds 1-12 were confirmed using rotating frame nuclear overhauser effect spectroscopy (ROESY), the circular dichroic (CD) exciton chirality method, and Rh2(OCOCF3)4-induced CD spectrum analysis. All of the isolated compounds were tested for hepatoprotective effects against D-galactosamine-induced cytotoxicity in HL-7702 hepatic cells. Compounds 1, 2, 7-12, and 17 showed significantly stronger hepatoprotective activity than the positive control bicyclol at a concentration of 1 × 10(-5) M.

  6. Assessing the Multiple Benefits of Clean Energy Chapter 1: Introduction (United States)

    Chapter 1 of “Assessing the Multiple Benefits of Clean Energy” provides an introduction to the document. /meta name=DC.title content=Assessing the Multiple Benefits of Clean Energy Chapter 1: Introduction

  7. Life story chapters, specific memories and the reminiscence bump

    DEFF Research Database (Denmark)

    Thomsen, Dorthe Kirkegaard; Pillemer, David B.; Ivcevic, Zorana


    Theories of autobiographical memory posit that extended time periods (here termed chapters) and memories are organised hierarchically. If chapters organise memories and guide their recall, then chapters and memories should show similar temporal distributions over the life course. Previous research...... demonstrates that positive but not negative memories show a reminiscence bump and that memories cluster at the beginning of extended time periods. The current study tested the hypotheses that (1) ages marking the beginning of positive but not negative chapters produce a bump, and that (2) specific memories...... are over-represented at the beginning of chapters. Potential connections between chapters and the cultural life script are also examined. Adult participants first divided their life story into chapters and identified their most positive and most negative chapter. They then recalled a specific memory from...

  8. An Experiment in Humanistic Management within Community College District Twelve, Centralia/Olympia, Washington. (United States)

    Miller, Dale A.; Hurley, John A.

    Community College District Twelve, a multi-college district serving a two-county area in southwestern Washington, has attempted to incorporate at administrative levels many of the humanistic, process-oriented principles of management discussed by Maslow and Maccoby. A concept of the ideal leadership style for District Twelve guides the selection…

  9. Columbia: The Economic Foundation of Peace. Chapters 21-28. (United States)

    Giugale, Marcelo M., Ed.; Lafourcade, Olivier, Ed.; Luff, Connie, Ed.

    This document contains 8 chapters of a 35-chapter book that presents a comprehensive diagnosis of current economic, social, and educational conditions in Colombia and their importance to development prospects and the quest for peace. The eight chapters covered here are part of a section titled "Sharing the Fruits of Growth with All…

  10. Space Applications of Mass Spectrometry. Chapter 31 (United States)

    Hoffman, John H.; Griffin, Timothy P.; Limero, Thomas; Arkin, C. Richard


    Mass spectrometers have been involved in essentially all aspects of space exploration. This chapter outlines some of these many uses. Mass spectrometers have not only helped to expand our knowledge and understanding of the world and solar system around us, they have helped to put man safely in space and expand our frontier. Mass spectrometry continues to prove to be a very reliable, robust, and flexible analytical instrument, ensuring that its use will continue to help aid our investigation of the universe and this small planet that we call home.

  11. Synthesis Gas Demonstration Plant, Baskett, Kentucky: environmental report. [Contains chapter 4 and appendix 4A

    Energy Technology Data Exchange (ETDEWEB)



    This volume contains chapter 4 and Appendix 4A which include descriptions of use of adjacent land and water (within miles of the proposed site), baseline ecology, air quality, meteorology, noise, hydrology, water quality, geology, soils and socio-economic factors. Appendix 4A includes detailed ecological surveys made in the area including the methods used. (LTN)

  12. Chapter 12: the anatomical foundations of clinical neurology. (United States)

    Bentivoglio, Marina; Mazzarello, Paolo


    The chapter provides an itinerary of knowledge on nervous system anatomy as one of the pillars of clinical neurology. The journey starts from the Renaissance explosion on the approach to the human body, its functions and its diseases, dealing with the seminal contributions of Leonardo da Vinci and Vesalius. The itinerary proceeds through the contributions of the 17th century, especially by Thomas Willis and the pioneering investigations of Marcello Malpighi and Antony van Leeuwenhoek, and onto the 18th century. The itinerary thus leads to the progress from gross anatomy to the microscopic investigation of the nervous system in the 19th century: the reticular theories, the revolution of the neural doctrine and their protagonists (Camillo Golgi and Santiago Ramón y Cajal), which initiated the modern era of the neurosciences. The chapter also includes sections on the contributions of developmental neuroanatomy to neurology, on the history of tract tracing, and on the cytoarchitecture of the cerebral cortex. The never-ending story of the anatomical foundations of clinical neurology continues to evolve at the dawn of the 21st century, including knowledge that guides deep brain stimulation, and novel approaches to the anatomy of the living brain based on rapidly developing neuroimaging technology.

  13. Environment. Chapter 5; Medio ambiente. Capitulo 5

    Energy Technology Data Exchange (ETDEWEB)

    Martin del Castillo, Carlos [Universidad Nacional Autonoma de Mexico, Mexico, D.F. (Mexico)


    In this chapter it is mentioned the concern for the care of the environment in Mexico by prominent foreign and Mexican scientists who impelled the creation of a Forest Law. The ecological policies for the conservation of natural resources that cause a sustainable development in Mexico are commented; it is described what the environmental infrastructure consists of; the case of trash handling is analyzed and the Chapter concludes with the relationship of the environment, the climatic change, the infrastructure and the planning. [Spanish] En este capitulo se menciona la preocupacion por el cuidado del medio ambiente en Mexico, por prominentes cientificos extranjeros y mexicanos que impulsaron la creacion de una Ley Forestal. Se comentan las politicas ecologicas para la conservacion de recursos naturales que propicien un desarrollo sustentable en Mexico; se describe en que consiste la infraestructura ambiental; se analiza el caso del manejo de la basura y; se concluye con la relacion del medio ambiente, el cambio climatico, la infraestructura y la planeacion.

  14. Universal Sensor and Actuator Requirements. Chapter 5 (United States)

    Rosenfeld, Taylor; Webster, John; Garg, Sanjay


    The previous chapters have focused on the requirements for sensors and actuators for "More Intelligent Gas Turbine Engines" from the perspective of performance and operating environment. Even if a technology is available, which meets these performance requirements, there are still various hurdles to be overcome for the technology to transition into a real engine. Such requirements relate to TRL (Technology Readiness Level), durability, reliability, volume, weight, cost, etc. This chapter provides an overview of such universal requirements which any sensor or actuator technology will have to meet before it can be implemented on a product. The objective here is to help educate the researchers or technology developers on the extensive process that the technology has to go through beyond just meeting performance requirements. The hope is that such knowledge will help the technology developers as well as decision makers to prevent wasteful investment in developing solutions to performance requirements, which have no potential to meet the "universal" requirements. These "universal" requirements can be divided into 2 broad areas: 1) Technology value proposition; and 2) Technology maturation. These requirements are briefly discussed in the following.

  15. Surface water quality in streams and rivers: introduction, scaling, and climate change: Chapter 5 (United States)

    Loperfido, John


    A variety of competing and complementary needs such as ecological health, human consumption, transportation, recreation, and economic value make management and protection of water resources in riverine environments essential. Thus, an understanding of the complex and interacting factors that dictate riverine water quality is essential in empowering stake-holders to make informed management decisions (see Chapter 1.15 for additional information on water resource management). Driven by natural and anthropogenic forcing factors, a variety of chemical, physical, and biological processes dictate riverine water quality, resulting in temporal and spatial patterns and cycling (see Chapter 1.2 for information describing how global change interacts with water resources). Furthermore, changes in climatic forcing factors may lead to long-term deviations in water quality outside the envelope of historical data. The goal of this chapter is to present fundamental concepts dictating the conditions of basic water quality parameters in rivers and streams (herein generally referred to as rivers unless discussing a specific system) in the context of temporal (diel (24 h) to decadal) longitudinal scaling. Understanding water quality scaling in rivers is imperative as water is continually reused and recycled (see also Chapters 3.1 and 3.15); upstream discharges from anthropogenic sources are incorporated into bulk riverine water quality that is used by downstream consumers. Water quality parameters reviewed here include temperature, pH, dissolved oxygen (DO), and suspended sediment and were selected given the abundance of data available for these parameters due to recent advances in water quality sensor technology (see Chapter 4.13 for use of hydrologic data in watershed management). General equations describing reactions affecting water temperature, pH, DO, and suspended sediment are included to convey the complexity of how simultaneously occurring reactions can affect water quality

  16. History of Artificial Gravity. Chapter 3 (United States)

    Clement, Gilles; Bukley, Angie; Paloski, William


    This chapter reviews the past and current projects on artificial gravity during space missions. The idea of a rotating wheel-like space station providing artificial gravity goes back in the writings of Tsiolkovsky, Noordung, and Wernher von Braun. Its most famous fictional representation is in the film 2001: A Space Odyssey, which also depicts spin-generated artificial gravity aboard a space station and a spaceship bound for Jupiter. The O Neill-type space colony provides another classic illustration of this technique. A more realistic approach to rotating the space station is to provide astronauts with a smaller centrifuge contained within a spacecraft. The astronauts would go into it for a workout, and get their gravity therapeutic dose for a certain period of time, daily or a few times a week. This simpler concept is current being tested during ground-based studies in several laboratories around the world.

  17. Mathematics Problem Solving: A More Advanced Skill for Chapter 1. Workshop Leader's Guide. (United States)

    Advanced Technology, Inc., Indianapolis, IN.

    This guide is designed to assist inservice providers in conducting successful workshops for teachers, administrators, and others associated with Chapter 1 mathematics programs. It contains step-by-step procedures for preparing, organizing, and presenting the workshop. Included in this guide are: (1) an advanced planner, which includes a detailed…

  18. Mercury and halogens in coal: Chapter 2 (United States)

    Kolker, Allan; Quick, Jeffrey C.; Granite, Evan J.; Pennline, Henry W.; Senior, Constance L.


    Apart from mercury itself, coal rank and halogen content are among the most important factors inherent in coal that determine the proportion of mercury captured by conventional controls during coal combustion. This chapter reviews how mercury in coal occurs, gives available concentration data for mercury in U.S. and international commercial coals, and provides an overview of the natural variation in halogens that influence mercury capture. Three databases, the U.S. Geological Survey coal quality (USGS COALQUAL) database for in-ground coals, and the 1999 and 2010 U.S. Environmental Protection Agency (EPA) Information Collection Request (ICR) databases for coals delivered to power stations, provide extensive results for mercury and other parameters that are compared in this chapter. In addition to the United States, detailed characterization of mercury is available on a nationwide basis for China, whose mean values in recent compilations are very similar to the United States in-ground mean of 0.17 ppm mercury. Available data for the next five largest producers (India, Australia, South Africa, the Russian Federation, and Indonesia) are more limited and with the possible exceptions of Australia and the Russian Federation, do not allow nationwide means for mercury in coal to be calculated. Chlorine in coal varies as a function of rank and correspondingly, depth of burial. As discussed elsewhere in this volume, on a proportional basis, bromine is more effective than chlorine in promoting mercury oxidation in flue gas and capture by conventional controls. The ratio of bromine to chlorine in coal is indicative of the proportion of halogens present in formation waters within a coal basin. This ratio is relatively constant except in coals that have interacted with deep-basin brines that have reached halite saturation, enriching residual fluids in bromine. Results presented here help optimize mercury capture by conventional controls and provide a starting point for

  19. Chapter 40: history of neurology in France. (United States)

    Clarac, François; Boller, François


    The history of neurology in France is characterized by the very high degree of centralization in that country where "everything seems to happen in Paris," and yet the considerable degree of autonomous diversity in the evolution of some other medical schools such as Montpellier and Strasbourg. It could be argued that France saw the birth of clinical neurology as a separate discipline since Jean Martin Charcot at the Salpêtrière Hospital obtained a chair of diseases of the nervous system in 1892, a first in the history of the academic world. The chapter shows, however, that the work of Charcot was preceded by a long evolution in medical thinking, which culminated with the introduction of experimental medicine developed by Claude Bernard and François Magendie, and by the study of aphasia by Paul Broca and its localization of language in a specific area of the brain. Many of the great neurologists of France like Duchenne de Boulogne, Gilles de la Tourette, Joseph Babinski and Pierre Marie gravitated around Charcot while others like Charles-Edward Brown-Sequard and Jules Dejerine developed their talents independently. The history of Sainte-Anne Hospital further illustrates this independence. It also shows the relation between neurology and psychiatry with Henri Ey, Jean Delay and Pierre Deniker, who collaborated with Henri Laborit in the clinical development of chlorpromazine. Sainte Anne also saw the birth of modern neuropsychology with Henry Hécaen. Jean Talairach and his group developed human stereotaxic neurosurgery and a 3-dimensional brain atlas that is used around the world. The chapter also mentions institutions (the CNRS and INSERM) that have contributed to developments partially independently from medical schools. It concludes with a presentation of schools located outside of Paris that have played a significant role in the development of neurology. Six of the most important ones are described: Montpellier, Toulouse, Bordeaux, Strasbourg, Lyon, and

  20. Scarcity and Survival in El Salvador. Grades Six to Twelve. (United States)

    Stanford Univ., CA. Stanford Program on International and Cross Cultural Education.

    This unit, designed for use with students in grades 6-12, has two purposes: (1) to inform teachers and students about social and economic conditions in rural El Salvador; and (2) to teach students how to analyze the indicators of such social and economic conditions. The six included lessons incorporate reading, graphing, and critical thinking…

  1. Twelve Years of Telecollaboration: What We Have Learnt (United States)

    Sadler, Randall; Dooly, Melinda


    This article describes the evolution, over a 12-year period, of a telecollaborative project between two universities. The project focused on two teacher training courses that integrate in-class dialogic learning and flipped classroom materials. The authors begin by outlining the first years of the project, including an overview of the initial…

  2. Experiences gained by establishing the IAMG Student Chapter Freiberg (United States)

    Ernst, Sebastian M.; Liesenberg, Veraldo; Shahzad, Faisal


    The International Association for Mathematical Geosciences (IAMG) Student Chapter Freiberg was founded in 2007 at the Technische Universität Bergakademie Freiberg (TUBAF) in Germany by national and international graduate and undergraduate students of various geoscientific as well as natural science disciplines. The major aim of the IAMG is to promote international cooperation in the application and use of Mathematics in Geosciences research and technology. The IAMG encourages all types of students and young scientists to found and maintain student chapters, which can even receive limited financial support by the IAMG. Following this encouragement, generations of students at TUBAF have build up and established a prosperous range of activities. These might be an example and an invitation for other young scientists and institutions worldwide to run similar activities. We, some of the current and former students behind the student chapter, have organised talks, membership drives, student seminars, guest lectures, several short courses and even international workshops. Some notable short courses were held by invited IAMG distinguished lecturers. The topics included "Statistical analysis in the Earth Sciences using R - a language and environment for statistical computing and graphics", "Geomathematical Natural Resource Modeling" and "Introduction to Geostatistics for Environmental Applications and Natural Resources Evaluation: Basic Concepts and Examples". Furthermore, we conducted short courses by ourselves. Here, the topics included basic introductions into MATLAB, object oriented programming concepts for geoscientists using MATLAB and an introduction to the Keyhole Markup Language (KML). Most of those short courses lasted several days and provided an excellent and unprecedented teaching experience for us. We were given credit by attending students for filling gaps in our university's curriculum by providing in-depth and hands-on tutorials on topics, which were merely

  3. Twelve tips for creating trigger images for problem-based learning cases. (United States)

    Azer, Samy A


    A trigger is the starting point of problem-based learning (PBL) cases. It is usually in the form of 5-6 text lines that provide the key information about the main character (usually the patient), including 3-4 of patient's presenting problems. In addition to the trigger text, most programs using PBL include a visual trigger. This might be in the form of a single image, a series of images, a video clip, a cartoon, or even one of the patient's investigation results (e.g. chest X-ray, pathology report, or urine sample analysis). The main educational objectives of the trigger image are as follows: (1) to introduce the patient to the students; (2) to enhance students' observation skills; (3) to provide them with new information to add to the cues obtained from the trigger text; and (4) to stimulate students to ask questions as they develop their enquiry plan. When planned and delivered effectively, trigger images should be engaging and stimulate group discussion. Understanding the educational objectives of using trigger images and choosing appropriate images are the keys for constructing successful PBL cases. These twelve tips highlight the key steps in the successful creation of trigger images.


    Institute of Scientific and Technical Information of China (English)



    In many years' clinical practice, I used blood-letting method of “Twelve Well-points” to treat emergencies as coma, syncope, acute infantile convulsion, wind-stroke syndrome, hysteria, epilepsy, etc. and have achieved immediate results.

  5. 17 CFR 232.104 - Unofficial PDF copies included in an electronic submission. (United States)


    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Unofficial PDF copies included... Filing Requirements § 232.104 Unofficial PDF copies included in an electronic submission. (a) An... (§ 249.101 of this chapter) or a Form D (§ 239.500 of this chapter), may include one unofficial PDF copy...

  6. The myrmicine ant genus Metapone Forel (Hymenoptera: Formicidae): a global taxonomic review with descriptions of twelve new species. (United States)

    Taylor, Robert W; Alpert, Gary D


    The 28 known species of Metapone are monographed and illustrated. Twelve are described as new: M. africana, Gabon; M. balinensis, Bali, Indonesia; M. enigmatica, northeast New Guinea; M. hoelldobleri, northeast Queensland, Australia; M. javana, Java, Indonesia; M. manni, Viti Levu, Fiji; M. mathinnae, Flinders Island, Tasmania, Australia; M. philwardi, northeast New Guinea; M. salomonis, Guadalcanal, Solomon Islands; M. tecklini, northeast Queensland; M. titan, New Ireland, Papua New Guinea; M. wallaceana, Lombok, Indonesia; spp.n. New synonymies include M. greeni Forel = M. johni Karavaiev (Sri Lanka) syn.n, and M. jacobsoni Crawley (Sumatra) = M. nicobarensis Tiwari & Jonathan (Great Nicobar Island) syn.n.

  7. Structural equation modeling: building and evaluating causal models: Chapter 8 (United States)

    Grace, James B.; Scheiner, Samuel M.; Schoolmaster, Donald R.


    Scientists frequently wish to study hypotheses about causal relationships, rather than just statistical associations. This chapter addresses the question of how scientists might approach this ambitious task. Here we describe structural equation modeling (SEM), a general modeling framework for the study of causal hypotheses. Our goals are to (a) concisely describe the methodology, (b) illustrate its utility for investigating ecological systems, and (c) provide guidance for its application. Throughout our presentation, we rely on a study of the effects of human activities on wetland ecosystems to make our description of methodology more tangible. We begin by presenting the fundamental principles of SEM, including both its distinguishing characteristics and the requirements for modeling hypotheses about causal networks. We then illustrate SEM procedures and offer guidelines for conducting SEM analyses. Our focus in this presentation is on basic modeling objectives and core techniques. Pointers to additional modeling options are also given.

  8. Twelve tips for constructing problem-based learning cases. (United States)

    Azer, Samy A; Peterson, Ray; Guerrero, Anthony P S; Edgren, Gudrun


    One of the key elements for introducing a problem-based learning (PBL) programme is constructing good PBL cases. Good cases should reflect the educational principles of PBL including (a) integration of basic and clinical sciences together with professionalism and psychosocial components, (b) encouragement of discussion of cognitive domains such as identification of problems, generation of hypotheses, construction of an enquiry plan, weighing evidence for and against each hypothesis, interpretation of findings, construction of mechanisms, using evidence to refine the hypothesis and construction of a management plan, (c) encouragement of discussion of cases in small groups with an emphasis on student-centred learning, (d) promotion of collaborative learning and contribution of students to the case discussion and (e) encouragement of teamwork and self-directed learning strategies. Despite the importance of construction of good PBL cases to the success of a PBL programme, the art of construction of these cases is understudied or described in the literature. Based on our experience in PBL and evidence from literature, we described 12 tips for constructing good PBL cases. Constructing good PBL cases is an art that necessitates teamwork and input from several different disciplines. Cases should be constructed using a template reflecting the educational objectives of the programme. This approach will ensure optimum learning outcomes and consistency in the design and delivery of cases.

  9. Chapter 14: Web-based Tools - WESIX (United States)

    Krughoff, K. S.; Connolly, A. J.

    We present here the design and features of the Web Enabled Source Identifier with X-Matching (WESIX). With the proliferation of large imaging surveys, it has become increasingly apparent that tasks performed frequently by astronomers need to be made available in a web-aware manner. The reasons for this are twofold: First, it is no longer feasible to work with the complete data sets. Calculations are much more efficient if they can be carried out at the data center where large files can be transferred quickly. Second, exploratory science can be greatly facilitated by combining common tasks into integrated web services. WESIX addresses both of these issues. It is deployable to large data centers where source identification can be carried out at the data source. In addition, WESIX can transparently leverage the capabilities of Open SkyQuery to crossmatch with large catalogs. The result is a web-based service that integrates object detection with the ability to crossmatch against published catalog data. In this chapter we will discuss how WESIX is constructed, its functionality and some example usage. Section 1 will give a brief overview of the architecture of the service. Section 2 will introduce the features of the service through both the web browser and SOAP web service interfaces. Section 3 gives a detailed overview of the web service methods. Section 4 walks through the example client distributed with the software package.

  10. Energy. Chapter 4; Energia. Capitulo 4

    Energy Technology Data Exchange (ETDEWEB)

    Martin del Castillo, Carlos [Universidad Nacional Autonoma de Mexico, Mexico, D.F. (Mexico)


    This chapter stands out that the infrastructure for the electric energy generation, as well as the one departing from fossil fuels has been the responsibility of two institutions with great solvency in the scope of engineering: the Comision Federal de Electricidad (CFE) and Petroleos Mexicanos (PEMEX). It is presented here the energy future in a sustainable context; a prospective study to year 2050; a strategic proposal of Petroleos Mexicanos; the forecast of the oil industry in Mexico and a technological prospective of the energy. [Spanish] En este capitulo se destaca que la infraestructura para la generacion de energia, tanto electrica como a partir de combustibles fisiles ha corrido a cargo de dos instituciones con gran solvencia en el ambito de la ingenieria: la Comision Federal de Electricidad (CFE) y Petroleos Mexicanos (Pemex). Se presenta el futuro de la energia en un contexto sustentable; un estudio prospectivo al ano 2050; una propuesta estrategica de Petroleos Mexicanos; la prospectiva de la industria petrolera en Mexico y; una prospectiva tecnologica de la energia.

  11. Carbon cycling in terrestrial environments: Chapter 17 (United States)

    Wang, Yang; Huntington, Thomas G.; Osher, Laurie J.; Wassenaar, Leonard I; Trumbore, Susan E.; Amundson, Ronald; Harden, Jennifer W.; McKnight, Diane M.; Schiff, Sherry L.; Aiken, George R.; Lyons, W. Berry; Aravena, Ramon O.; Baron, Jill S.


    This chapter reviews a number of applications of isotopic techniques for the investigation of carbon cycling processes. Carbon dioxide (C02) is an important greenhouse gas. Its concentration in the atmosphere has increased from an estimated 270 ppm at the beginning of the industrial revolution to ∼ 360 ppm at present. Climatic conditions and atmospheric C02 concentration also influence isotopic discrimination during photosynthesis. Natural and anthropogenically induced variations in the carbon isotopic abundance can be exploited to investigate carbon transformations between pools on various time scales. It also discusses one of the isotopes of carbon, the 14C, that is produced in the atmosphere by interactions of cosmic-ray produced neutrons with stable isotopes of nitrogen (N), oxygen (O), and carbon (C), and has a natural abundance in the atmosphere of ∼1 atom 14 C per 1012 atoms 12C. The most important factor affecting the measured 14C ages of soil organic matter is the rate of organic carbon cycling in soils. Differences in the dynamics of soil carbon among different soils or soil horizons will result in different soil organic 14C signatures. As a result, the deviation of the measured 14C age from the true age could differ significantly among different soils or soil horizons.

  12. Chapter 3: Small molecules and disease.

    Directory of Open Access Journals (Sweden)

    David S Wishart

    Full Text Available "Big" molecules such as proteins and genes still continue to capture the imagination of most biologists, biochemists and bioinformaticians. "Small" molecules, on the other hand, are the molecules that most biologists, biochemists and bioinformaticians prefer to ignore. However, it is becoming increasingly apparent that small molecules such as amino acids, lipids and sugars play a far more important role in all aspects of disease etiology and disease treatment than we realized. This particular chapter focuses on an emerging field of bioinformatics called "chemical bioinformatics"--a discipline that has evolved to help address the blended chemical and molecular biological needs of toxicogenomics, pharmacogenomics, metabolomics and systems biology. In the following pages we will cover several topics related to chemical bioinformatics. First, a brief overview of some of the most important or useful chemical bioinformatic resources will be given. Second, a more detailed overview will be given on those particular resources that allow researchers to connect small molecules to diseases. This section will focus on describing a number of recently developed databases or knowledgebases that explicitly relate small molecules--either as the treatment, symptom or cause--to disease. Finally a short discussion will be provided on newly emerging software tools that exploit these databases as a means to discover new biomarkers or even new treatments for disease.

  13. Moving forward with imperfect information: chapter 19 (United States)

    Averyt, Kristen; Brekke, Levi D.; Kaatz, Laurna; Welling, Leigh; Hartge, Eric H.; Iseman, Tom


    This chapter summarized the scope of what is known and not known about climate in the Southwestern United States. There is now more evidence and more agreement among climate scientists about the physical climate and related impacts in the Southwest compared with that represented in the 2009 National Climate Assessment (Karl, Melillo, and Peterson 2009). However, there remain uncertainties about the climate system, the complexities within climate models, the related impacts to the biophysical environment, and the use of climate information on decision making. Uncertainty is introduced in each step of the climate planning-an-response process--in the scenarios used to drive the climate models, the information used to construct the models, and the interpretation and use of the model' data for planning and decision making (Figure 19.1). There are server key challenge, drawn from recommendations of the authors of this report, that contribute to these uncertainties in the Southwest: - There is a dearth of climate observations at high elevations and on the lands of Native nations.

  14. Chapter 15: Integration and (De-)installation

    CERN Document Server

    Fessia, P.


    Chapter 15 in High-Luminosity Large Hadron Collider (HL-LHC) : Preliminary Design Report. The Large Hadron Collider (LHC) is one of the largest scientific instruments ever built. Since opening up a new energy frontier for exploration in 2010, it has gathered a global user community of about 7,000 scientists working in fundamental particle physics and the physics of hadronic matter at extreme temperature and density. To sustain and extend its discovery potential, the LHC will need a major upgrade in the 2020s. This will increase its luminosity (rate of collisions) by a factor of five beyond the original design value and the integrated luminosity (total collisions created) by a factor ten. The LHC is already a highly complex and exquisitely optimised machine so this upgrade must be carefully conceived and will require about ten years to implement. The new configuration, known as High Luminosity LHC (HL-LHC), will rely on a number of key innovations that push accelerator technology beyond its present limits. Amo...


    Energy Technology Data Exchange (ETDEWEB)

    Mazeh, Tsevi; Nachmani, Gil; Holczer, Tomer; Sokol, Gil [School of Physics and Astronomy, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978 (Israel); Fabrycky, Daniel C. [Department of Astronomy and Astrophysics, University of Chicago, 5640 Ellis Ave., Chicago, IL 60637 (United States); Ford, Eric B.; Ragozzine, Darin [Astronomy Department, University of Florida, Gainesville, FL 32111 (United States); Sanchis-Ojeda, Roberto [Department of Physics and Kavli Institute for Astrophysics and Space Research, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Rowe, Jason F.; Lissauer, Jack J. [NASA Ames Research Center, Moffett Field, CA 94035 (United States); Zucker, Shay [Department of Geophysical, Atmospheric and Planetary Sciences, Raymond and Beverly Sackler Faculty of Exact Sciences Tel Aviv University, 69978 Tel Aviv (Israel); Agol, Eric [Department of Astronomy, Box 351580, University of Washington, Seattle, WA 98195 (United States); Carter, Joshua A. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Quintana, Elisa V. [SETI Institute, 189 Bernardo Ave, Suite 100, Mountain View, CA 94043 (United States); Steffen, Jason H. [Fermilab Center for Particle Astrophysics, P.O. Box 500, MS 127, Batavia, IL 60510 (United States); Welsh, William [Astronomy Department, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182 (United States)


    Following the works of Ford et al. and Steffen et al. we derived the transit timing of 1960 Kepler objects of interest (KOIs) using the pre-search data conditioning light curves of the first twelve quarters of the Kepler data. For 721 KOIs with large enough signal-to-noise ratios, we obtained also the duration and depth of each transit. The results are presented as a catalog for the community to use. We derived a few statistics of our results that could be used to indicate significant variations. Including systems found by previous works, we have found 130 KOIs that showed highly significant times of transit variations (TTVs) and 13 that had short-period TTV modulations with small amplitudes. We consider two effects that could cause apparent periodic TTV—the finite sampling of the observations and the interference with the stellar activity, stellar spots in particular. We briefly discuss some statistical aspects of our detected TTVs. We show that the TTV period is correlated with the orbital period of the planet and with the TTV amplitude.

  16. Peer teaching in medical education: twelve reasons to move from theory to practice. (United States)

    Ten Cate, Olle; Durning, Steven


    To provide an estimation of how often peer teaching is applied in medical education, based on reports in the literature and to summarize reasons that support the use of this form of teaching. We surveyed the 2006 medical education literature and categorised reports of peer teaching according to educational distance between students teaching and students taught, group size, and level of formality of the teaching. Subsequently, we analysed the rationales for applying peer teaching. Most reports were published abstracts in either Medical Education's annual feature 'Really Good Stuff' or the AMEE's annual conference proceedings. We identified twelve distinct reasons to apply peer teaching, including 'alleviating faculty teaching burden', 'providing role models for junior students', 'enhancing intrinsic motivation' and 'preparing physicians for their future role as educators'. Peer teaching appears to be practiced often, but many peer teaching reports do not become full length journal articles. We conclude that specifically 'near-peer teaching' appears beneficial for student teachers and learners as well as for the organisation. The analogy of the 'journeyman', as intermediate between 'apprentice' and 'master', with both learning and teaching tasks, is a valuable but yet under-recognized source of education in the medical education continuum.

  17. Whole-Proteome Analysis of Twelve Species of Alphaproteobacteria Links Four Pathogens

    Directory of Open Access Journals (Sweden)

    Yunyun Zhou


    Full Text Available Thousands of whole-genome and whole-proteome sequences have been made available through advances in sequencing technology, and sequences of millions more organisms will become available in the coming years. This wealth of genetic information will provide numerous opportunities to enhance our understanding of these organisms including a greater understanding of relationships among species. Researchers have used 16S rRNA and other gene sequences to study the evolutionary origins of bacteria, but these strategies do not provide insight into the sharing of genes among bacteria via horizontal transfer. In this work we use an open source software program called pClust to cluster proteins from the complete proteomes of twelve species of Alphaproteobacteria and generate a dendrogram from the resulting orthologous protein clusters. We compare the results with dendrograms constructed using the 16S rRNA gene and multiple sequence alignment of seven housekeeping genes. Analysis of the whole proteomes of these pathogens grouped Rickettsia typhi with three other animal pathogens whereas conventional sequence analysis failed to group these pathogens together. We conclude that whole-proteome analysis can give insight into relationships among species beyond their phylogeny, perhaps reflecting the effects of horizontal gene transfer and potentially providing insight into the functions of shared genes by means of shared phenotypes.


    Directory of Open Access Journals (Sweden)

    Adebowale Odeyemi


    Full Text Available The incidence and survival of lipolytic organisms in domestic wastewater and receiving stream were monitored over 12 months. The average total bacterial count in the wastewater samples reduced in April and November by 24.2% and 41.6% respectively. There was also a reduction of 42.3% and 60.1% in the load in the receiving stream in August and July. Subsequently, at 5m downstream from the entry of the wastewater the microbial load reduced in March (19.2% and June (19.2%. However, the occurrence of coliforms was more affected in the months of May (53% to July (87.2%. At 5m and 10m downstream the coliform population reduced by 27.9% and 30.1% respectively. Of the twelve (12 bacterial isolates obtained at the exit of the wastewater into the receiving stream, only four (4 were found to possess lipolytic activity. These include the species of Enterococcus, Klebsiella, Pseudomonas and Staphylococcus. There was no significant difference in the amount of nutrients found in the domestic wastewater and receiving stream during the months. This paper also discusses the implication of disposing large amounts of wastewater effluents into the receiving water and the need to remedy and minimize the overall impact of such pollution on the environment.

  19. Differences in antimicrobial activity of chlorine against twelve most prevalent poultry-associated Salmonella serotypes. (United States)

    Paul, Narayan C; Sullivan, Tarah S; Shah, Devendra H


    Chlorine is the most widely used carcass sanitizer in poultry processing in the USA. The objective of this study was to determine the effects of varying concentrations of organic matter on the susceptibility of twelve most prevalent poultry-associated Salmonella serotypes (MPPSTs) to chlorine. To mimic the microenvironment of the water used for immersion chilling, we manipulated organic matter contamination levels in pre-chilled (pH∼6, T∼4 °C) chlorinated (50 ppm) water using varying concentrations (0, 1, 2, 3, 4, and 5%) of chicken-meat-extract (CME) produced from frozen chicken carcasses. This CME-based in vitro model was challenged with ∼1 × 10(5) CFUs of each MPPST isolate and the bacterial survival was tested at 5, 30, 60 and 90 min post-challenge. In this model, the decimal reduction time (D90-values) of each MPPST was linearly correlated with the concentration of CME. Significant inter-serotype differences in the D90-values were observed. The results show that the pH, concentration of total- and free-chlorine were also linearly correlated with the presence of CME in a concentration-dependent manner. The findings of this study indicate that the serotype and the levels of organic matter contamination significantly influence Salmonella survival and that both variables should be included in models that predict effectiveness of chlorine treatment in immersion chilling.

  20. Electricity production from twelve monosaccharides using microbial fuel cells

    Energy Technology Data Exchange (ETDEWEB)

    Catal, Tunc [Department of Biological and Ecological Engineering, Oregon State University, 116 Gilmore Hall, Corvallis, OR 97331 (United States); Department of Wood Science and Engineering, Oregon State University, 102 Richardson Hall, Corvallis, OR 97331 (United States); Department of Molecular Biology and Genetics, Istanbul Technical University, 34469-Maslak, Istanbul (Turkey); Li, Kaichang [Department of Wood Science and Engineering, Oregon State University, 102 Richardson Hall, Corvallis, OR 97331 (United States); Bermek, Hakan [Department of Molecular Biology and Genetics, Istanbul Technical University, 34469-Maslak, Istanbul (Turkey); Liu, Hong [Department of Biological and Ecological Engineering, Oregon State University, 116 Gilmore Hall, Corvallis, OR 97331 (United States)


    Direct generation of electricity from monosaccharides of lignocellulosic biomass was examined using air cathode microbial fuel cells (MFCs). Electricity was generated from all carbon sources tested, including six hexoses (D-glucose, D-galactose, D(-)-levulose (fructose), L-fucose, L-rhamnose, and D-mannose), three pentoses (D-xylose, D(-)-arabinose, and D(-)-ribose), two uronic acids (D-galacturonic acid and D-glucuronic acid) and one aldonic acid (D-gluconic acid). The mixed bacterial culture, which was enriched using acetate as a carbon source, adapted well to all carbon sources tested, although the adaptation times varied from 1 to 70 h. The maximum power density obtained from these carbon sources ranged from 1240 {+-} 10 to 2770 {+-} 30 mW m{sup -2} at current density range of 0.76-1.18 mA cm{sup -2}. D-Mannose resulted in the lowest maximum power density, whereas D-glucuronic acid generated the highest one. Coulombic efficiency ranged from 21 to 37%. For all carbon sources tested, the relationship between the maximum voltage output and the substrate concentration appeared to follow saturation kinetics at 120 {omega} external resistance. The estimated maximum voltage output ranged between 0.26 and 0.44 V and half-saturation kinetic constants ranged from 111 to 725 mg L{sup -1}. Chemical oxygen demand (COD) removal was over 80% for all carbon sources tested. Results from this study indicated that lignocellulosic biomass-derived monosaccharides might be a suitable resource for electricity generation using MFC technology. (author)

  1. Electricity production from twelve monosaccharides using microbial fuel cells (United States)

    Catal, Tunc; Li, Kaichang; Bermek, Hakan; Liu, Hong

    Direct generation of electricity from monosaccharides of lignocellulosic biomass was examined using air cathode microbial fuel cells (MFCs). Electricity was generated from all carbon sources tested, including six hexoses (D-glucose, D-galactose, D(-)-levulose (fructose), L-fucose, L-rhamnose, and D-mannose), three pentoses (D-xylose, D(-)-arabinose, and D(-)-ribose), two uronic acids (D-galacturonic acid and D-glucuronic acid) and one aldonic acid (D-gluconic acid). The mixed bacterial culture, which was enriched using acetate as a carbon source, adapted well to all carbon sources tested, although the adaptation times varied from 1 to 70 h. The maximum power density obtained from these carbon sources ranged from 1240 ± 10 to 2770 ± 30 mW m -2 at current density range of 0.76-1.18 mA cm -2. D-Mannose resulted in the lowest maximum power density, whereas D-glucuronic acid generated the highest one. Coulombic efficiency ranged from 21 to 37%. For all carbon sources tested, the relationship between the maximum voltage output and the substrate concentration appeared to follow saturation kinetics at 120 Ω external resistance. The estimated maximum voltage output ranged between 0.26 and 0.44 V and half-saturation kinetic constants ranged from 111 to 725 mg L -1. Chemical oxygen demand (COD) removal was over 80% for all carbon sources tested. Results from this study indicated that lignocellulosic biomass-derived monosaccharides might be a suitable resource for electricity generation using MFC technology.

  2. Microbial air-sampling equipment, part 1: meeting United States pharmacopeia chapter 797 standards. (United States)

    Kastango, Eric S


    The most recent changes to Chapter 797 of the United States Pharmcopeia-National Formulary initiated an intense controversy about the frequency of cleanroom air sampling that is required to prevent the contamination of sterile preparations. For compounders who must purchase an air sampler to use in the cleanroom, choices abound. Included in this article are a review of United States Pharmacopeia-National Formulary requirements that pertain to air sampling, a discussion of how recent revision to Chapter 797 affect air sampling and patient safety, and, for easy reference, a table that features specifications for various models of microbial air samplers.

  3. Implementation of the Takeover Bids Directive in the Netherlands : Chapter 12

    NARCIS (Netherlands)

    Cremers, Jan; van Het Kaar, R.H.; Cremers, Jan; Vitols, Sigurt


    Chapter dedicated to the Dutch implementation of EU Takeover Bids Directive. The case is particularly interesting because of the strong position of works councils within Dutch companies, including in restructuring situations. Implementation of the Takeover Bids Directive in the Netherlands did not l

  4. After "Aguilar v. Felton": Chapter 1 Services for Massachusetts Nonpublic School Students. Final Report. (United States)

    Millsap, Mary Ann; Wilber, Nancy

    In July 1985 the Supreme Court ruled in Aguilar v. Felton that public school employees could no longer provide instruction, including Chapter 1 services, on religious school premises, previously the most common service delivery model used. This study addresses the following questions: (1) what portion of the decline in services to nonpublic school…

  5. Creating historical range of variation (HRV) time series using landscape modeling: Overview and issues [Chapter 8 (United States)

    Robert E. Keane


    Simulation modeling can be a powerful tool for generating information about historical range of variation (HRV) in landscape conditions. In this chapter, I will discuss several aspects of the use of simulation modeling to generate landscape HRV data, including (1) the advantages and disadvantages of using simulation, (2) a brief review of possible landscape models. and...

  6. A Comparison of Preschool Children's Discussions with Parents during Picture Book and Chapter Book Reading (United States)

    Leech, Kathryn A.; Rowe, Meredith L.


    Discussions that occur during book reading between parents and preschool children relate to children's language development, especially discussions during picture books that include extended discourse, a form of abstract language. While a recent report shows increased chapter book reading among families with preschool children, it is unknown…

  7. Implementation of the Takeover Bids Directive in the Netherlands : Chapter 12

    NARCIS (Netherlands)

    Cremers, Jan; van Het Kaar, R.H.; Cremers, Jan; Vitols, Sigurt


    Chapter dedicated to the Dutch implementation of EU Takeover Bids Directive. The case is particularly interesting because of the strong position of works councils within Dutch companies, including in restructuring situations. Implementation of the Takeover Bids Directive in the Netherlands did not

  8. Twelve Years of Education and Public Outreach with the Fermi Gamma-ray Space Telescope (United States)

    Cominsky, Lynn R.; McLin, K. M.; Simonnet, A.; Fermi E/PO Team


    During the past twelve years, NASA's Fermi Gamma-ray Space Telescope has supported a wide range of Education and Public Outreach (E/PO) activities, targeting K-14 students and the general public. The purpose of the Fermi E/PO program is to increase student and public understanding of the science of the high-energy Universe, through inspiring, engaging and educational activities linked to the mission’s science objectives. The E/PO program has additional more general goals, including increasing the diversity of students in the Science, Technology, Engineering and Mathematics (STEM) pipeline, and increasing public awareness and understanding of Fermi science and technology. Fermi's multi-faceted E/PO program includes elements in each major outcome category: ● Higher Education: Fermi E/PO promotes STEM careers through the use of NASA data including research experiences for students and teachers (Global Telescope Network), education through STEM curriculum development projects (Cosmology curriculum) and through enrichment activities (Large Area Telescope simulator). ● Elementary and Secondary education: Fermi E/PO links the science objectives of the Fermi mission to well-tested, customer-focused and NASA-approved standards-aligned classroom materials (Black Hole Resources, Active Galaxy Education Unit and Pop-up book, TOPS guides, Supernova Education Unit). These materials have been distributed through (Educator Ambassador and on-line) teacher training workshops and through programs involving under-represented students (after-school clubs and Astro 4 Girls). ● Informal education and public outreach: Fermi E/PO engages the public in sharing the experience of exploration and discovery through high-leverage multi-media experiences (Black Holes planetarium and PBS NOVA shows), through popular websites (Gamma-ray Burst Skymap, Epo's Chronicles), social media (Facebook, MySpace), interactive web-based activities (Space Mysteries, Einstein@Home) and activities by

  9. Improving the Identification of Schools for Chapter 1 Program Improvement. (United States)

    D'Agostino, Jerome

    Technical problems with norm-referenced achievement testing that can lead to the erroneous evaluation of schools for Chapter 1 Program improvement is discussed, and an alternative testing model is presented. The history of Chapter 1 testing and evaluation policies is briefly reviewed, and problems with the norm-referenced model are explored. Data…

  10. Ocular hypotensive effect, preservation of visual fields, and safety of adding dorzolamide to prostaglandin therapy for twelve months

    Directory of Open Access Journals (Sweden)

    Kenji Inoue


    Full Text Available Kenji Inoue1,3, Mieko Masumoto1,3, Masato Wakakura1, Goji Tomita2, On behalf of the Ochanomizu Ophthalmology Study Group31Inouye Eye Hospital, Tokyo, Japan; 2Department of Ophthalmology, Toho University School of Medicine, Tokyo, Japan; 3Ochanomizu Ophthalmology, Tokyo, JapanPurpose: To prospectively evaluate the safety, hypotensive effect, and preservation of visual fields of dorzolamide when added to latanoprost.Subjects and methods: This study included 46 patients (46 eyes with primary open-angle glaucoma who had been treated with latanoprost. Dorzolamide (1% was added to latanoprost, and the intraocular pressure (IOP was monitored before and after 3, 6, and 12 months. The mean deviation shown by Humphrey perimetry was compared before and after twelve months of treatment. Adverse reactions were monitored over the 12-month study period.Results: The mean baseline IOP was 17.2 ± 3.0 mmHg while those after 3, 6 and 12 months of treatment were 14.9 ± 3.0 mmHg, 14.5 ± 3.2 mmHg, and 14.6 ± 2.6 mmHg respectively (P < 0.0001, 1-ß(power = 0.9999571. The absolute reduction of IOP and the percent reduction were similar after 3, 6, and 12 months of treatment. The mean deviation on Humphrey perimetry was similar before and after twelve months of treatment. Three patients discontinued dorzolamide therapy due to elevation of IOP and one patient discontinued it because of adverse reactions.Conclusion: Dorzolamide is safe and effective when used for twelve months as add-on therapy to latanoprost for open-angle glaucoma.Keywords: dorzolamide, primary open-angle glaucoma, latanoprost 

  11. Do supervised weekly exercise programs maintain functional exercise capacity and quality of life, twelve months after pulmonary rehabilitation in COPD?

    Directory of Open Access Journals (Sweden)

    Alison Jennifer A


    Full Text Available Abstract Background Pulmonary rehabilitation programs have been shown to increase functional exercise capacity and quality of life in COPD patients. However, following the completion of pulmonary rehabilitation the benefits begin to decline unless the program is of longer duration or ongoing maintenance exercise is followed. Therefore, the aim of this study is to determine if supervised, weekly, hospital-based exercise compared to home exercise will maintain the benefits gained from an eight-week pulmonary rehabilitation program in COPD subjects to twelve months. Methods Following completion of an eight-week pulmonary rehabilitation program, COPD subjects will be recruited and randomised (using concealed allocation in numbered envelopes into either the maintenance exercise group (supervised, weekly, hospital-based exercise or the control group (unsupervised home exercise and followed for twelve months. Measurements will be taken at baseline (post an eight-week pulmonary rehabilitation program, three, six and twelve months. The exercise measurements will include two six-minute walk tests, two incremental shuttle walk tests, and two endurance shuttle walk tests. Oxygen saturation, heart rate and dyspnoea will be monitored during all these tests. Quality of life will be measured using the St George's Respiratory Questionnaire and the Hospital Anxiety and Depression Scale. Participants will be excluded if they require supplemental oxygen or have neurological or musculoskeletal co-morbidities that will prevent them from exercising independently. Discussion Pulmonary rehabilitation plays an important part in the management of COPD and the results from this study will help determine if supervised, weekly, hospital-based exercise can successfully maintain functional exercise capacity and quality of life following an eight-week pulmonary rehabilitation program in COPD subjects in Australia.

  12. Chapter A3. Cleaning of Equipment for Water Sampling (United States)

    Wilde, Franceska D.; Radtke, Dean B.; Gibs, Jacob; Iwatsubo, Rick T.


    The National Field Manual for the Collection of Water-Quality Data (National Field Manual) describes protocols and provides guidelines for U.S. Geological Survey (USGS) personnel who collect data used to assess the quality of the Nation's surface-water and ground-water resources. Chapter A3 describes procedures for cleaning the equipment used to collect and process samples of surface water and ground water and procedures for assessing the efficacy of the equipment-cleaning process. This chapter is designed for use with the other chapters of this field manual. Each chapter of the National Field Manual is published separately and revised periodically. Newly published and revised chapters will be posted on the USGS page 'National Field Manual for the Collection of Water-Quality Data.' The URL for this page is (accessed September 20, 2004).

  13. The Life Cycle Completed. Extended Version with New Chapters on the Ninth Stage of Development by Joan M. Erikson. (United States)

    Erikson, Erik H.

    This expanded edition of a 1982 book by Erik Erikson summarizes his work on the stages of the human life cycle, including chapters on psychosexuality and the cycle of generations, major stages in psychosocial development, and ego and ethos. An additional chapter on the ninth stage sets forth his philosophy on old age--i.e. the 80s and 90s--and how…

  14. Getting the Most from Pi Sigma Alpha Chapters: Exploring the Chapter Activity Grant Program and Its Multiplier Effects (United States)

    Alexander, Robert M.


    The political science honor society, Pi Sigma Alpha, has chapters in nearly 700 institutions across the United States. The organization sponsors many programs that can contribute a great deal to students of political science; however, many students are unaware of these opportunities. This article encourages chapter advisors to make use of these…

  15. Deathly silence and apocalyptic noise: Observations on the soundscape of the Book of the Twelve

    Directory of Open Access Journals (Sweden)

    Aaron Schart


    Full Text Available This paper proposes a reading of the Book of the Twelve (used interchangeably with �Twelve� and �Book� for convenience that concentrates on the sound that is included in the description of the world of the text. Three onomatopoeic devices are singled out. First, the mourning cry h�y is considered. This interjection is used differently in several of the writings: in Amos (5:18; 6:1 the prophet cries out in compassion with the addressees. By contrast, in Nahum 3:1 and Habakkuk 2:6�19, h�y is uttered in a mood of mockery. In Zechariah 2:10 a third, joyful h�y is used. It appears that the different usages cohere nicely with the overall structure of the Book of the Twelve. Secondly, the interjection has likewise shows different usages. In Amos 6:10 and 8:3, it simulates the last breath of Israelites dying when the land is devastated. By contrast, in Habakkuk 2:20, Zephaniah 1:7 and Zechariah 2:17, the addressees are directed to be silent before YHWH. This command should be perceived as an act of reverence. Again, the sequence of the occurrences coheres with the overall structure of the Book of the Twelve. Of special relevance is that the last three instances build a frame around the Babylonian exile, which lies between Zephaniah and Haggai. The third example is the phrase ham�n�m, ham�n�m in Joel 4:14. The author employs an irregular double plural to construe this place as the loudest spot (�apocalyptic noise� within the Twelve.Setu sa go tiba le modumo wa aphokhaliptiki: Ditemogo ka medumo ya Puku ya ba LesomepediPampiri ye e �i�inya go balwa ga Puku ya ba Lesomepedi (yeo e ka nogo bit�wa �Lesomepedi� goba �Puku� go bebofat�a ditaba ka go gatelela modumo wo o lego ka gare ga tlhaloso ya lefase la go tswala dingwalo t�e. Ditsela t�e tharo t�a onomathopoiki di bewa pepeneng. La mathomo, go �et�wa sello sa mahloko sa h?y. Lelahlelwa le le �omi�wa ka go fapana mo dingwalong t�e mmalwa: go Amosi

  16. Twelve new species and fifty-three new provincial distribution records of Aleocharinae rove beetles of Saskatchewan, Canada (Coleoptera, Staphylinidae). (United States)

    Klimaszewski, Jan; Larson, David J; Labrecque, Myriam; Bourdon, Caroline


    One hundred twenty species of aleocharine beetles (Staphylinidae) are recognized in the province of Saskatchewan. Sixty-five new provincial records, including twelve new species and one new North American record, are presented. Oligota inflata (Mannerheim), a Palearctic species, is newly recorded for North America. The following twelve species are described as new to science: Acrotona pseudopygmaea Klimaszewski & Larson, sp. n., Agaricomorpha pulchra Klimaszewski & Larson, sp. n. (new genus record for Canadian fauna), Aleochara elisabethae Klimaszewski & Larson, sp. n., Atheta (Dimetrota) larsonae Klimaszewski & Larson, sp. n., Atheta (Microdota) pseudopittionii Klimaszewski & Larson, sp. n., Atheta (Microdota) spermathecorum Klimaszewski & Larson, sp. n., Atheta (sensu lato) richardsoni Klimaszewski & Larson, sp. n., Brachyusa saskatchewanae Klimaszewski & Larson, sp. n., Dochmonota langori Klimaszewski & Larson, sp. n., Dochmonota simulans Klimaszewski & Larson, sp. n., Dochmonota websteri Klimaszewski & Larson, sp. n., and Oxypoda domestica Klimaszewski & Larson, sp. n. Colour images of habitus and black and white images of the median lobe of the aedeagus, spermatheca, and tergite and sternite VIII are presented for all new species, Oligota inflata Mannerheim and Dochmonota rudiventris (Eppelsheim). A new synonymy is established: Tetralina filitarsus Casey, syn. n. = Tetralina helenae Casey, now placed in the genus Brachyusa Mulsant & Rey.

  17. A survey of innovation through duplication in the reduced genomes of twelve parasites.

    Directory of Open Access Journals (Sweden)

    Jeremy D DeBarry

    Full Text Available We characterize the prevalence, distribution, divergence, and putative functions of detectable two-copy paralogs and segmental duplications in the Apicomplexa, a phylum of parasitic protists. Apicomplexans are mostly obligate intracellular parasites responsible for human and animal diseases (e.g. malaria and toxoplasmosis. Gene loss is a major force in the phylum. Genomes are small and protein-encoding gene repertoires are reduced. Despite this genomic streamlining, duplications and gene family amplifications are present. The potential for innovation introduced by duplications is of particular interest. We compared genomes of twelve apicomplexans across four lineages and used orthology and genome cartography to map distributions of duplications against genome architectures. Segmental duplications appear limited to five species. Where present, they correspond to regions enriched for multi-copy and species-specific genes, pointing toward roles in adaptation and innovation. We found a phylum-wide association of duplications with dynamic chromosome regions and syntenic breakpoints. Trends in the distribution of duplicated genes indicate that recent, species-specific duplicates are often tandem while most others have been dispersed by genome rearrangements. These trends show a relationship between genome architecture and gene duplication. Functional analysis reveals: proteases, which are vital to a parasitic lifecycle, to be prominent in putative recent duplications; a pair of paralogous genes in Toxoplasma gondii previously shown to produce the rate-limiting step in dopamine synthesis in mammalian cells, a possible link to the modification of host behavior; and phylum-wide differences in expression and subcellular localization, indicative of modes of divergence. We have uncovered trends in multiple modes of duplicate divergence including sequence, intron content, expression, subcellular localization, and functions of putative recent duplicates that

  18. Site characterization plan: Yucca Mountain Site, Nevada Research and Development Area, Nevada: Volume 1, Part A: Chapters 1 and 2

    Energy Technology Data Exchange (ETDEWEB)



    This site characterization plan (SCP) has been developed for the candidate repository site at Yucca Mountain in the State of Nevada. The SCP includes a description of the Yucca Mountain site (Chapters 1-5), a conceptual design for the repository (Chapter 6), a description of the packaging to be used for the waste to be emplaced in the repository (Chapter 7), and a description of the planned site characterization activities (Chapter 8). The schedules and milestones presented in Sections 8.3 and 8.5 of the SCP were developed to be consistent with the June 1988 draft Amendment to the DOE`s Mission Plan for the Civilian Radioactive Waste Management Program. The five month delay in the scheduled start of exploratory shaft construction that was announced recently is not reflected in these schedules. 750 refs., 123 figs., 42 tabs.

  19. Quality-Control Analytical Methods: Microbial-Testing Aspects of USP Chapter 797 for Compounded Sterile Preparations. (United States)

    Kupiec, Thomas C


    The standards set forth by the United States Pharmacopeia (USP) Chapter 797 have now been in effect since January 1 or 2004. As the first practice standards of sterile pharmacy compounding in US history, they have "attracted both respect and criticism" because they have also been cited as a practice expectation by the Joint Commission on Accreditation of Healthcare Organizations. USP 797 expands the scope of facilities governed by the regulatinos and defines the practices covered, emphasizing the importance of environmental quality and control, verification of accuracy and sterility, training and evaluation, quality control after preparations leave the pharmacy, patient monitoring and adverse events reporting. The purpose of this article is to help the reader understand the criteria set forth by USP Chapter 797 regarding finished-product testing, including criteria for the microbial-testing aspects of sterility testing (USP Chapter 71) and endotoxin (pyrogen) testing (USP Chapter 85).

  20. Site Characterization Plan: Yucca Mountain Site, Nevada Research and Development Area, Nevada: Volume 3, Part A: Chapters 6 and 7

    Energy Technology Data Exchange (ETDEWEB)



    This site characterization plan (SCP) has been developed for the candidate repository site at Yucca Mountain in the State of Nevada. The SCP includes a description of the Yucca Mountain site (Chapters 1-5), a conceptual design for the repository (Chapter 6), a description of the packaging to be used for the waste to be emplaced in the repository (Chapter 7), and a description of the planned site characterization activities (Chapter 8). The schedules and milestones presented in Sections 8.3 and 8.5 of the SCP were developed to be consistent with the June 1988 draft Amendment to the DOE`s Mission Plan for the Civilian Radioactive Waste Management Program. The five month delay in the scheduled start of exploratory shaft construction that was announced recently is not reflected in these schedules. 218 figs., 50 tabs.

  1. Agreement between Bloomfield College and the Bloomfield College Chapter of the American Association of University Professors and Bloomfield College Faculty Personnel Procedures, July 1, 1985-June 30, 1987. (United States)

    Bloomfield Coll., NJ.

    The collective bargaining agreement between Bloomfield College and the Bloomfield College Chapter of AAUP covering the period July 1, 1985-June 30, 1987 is presented. Items covered in the agreement include: contract management, no strike/lockout, nondiscrimination, chapter rights, dues checkoff, academic freedom, faculty status and criteria for…

  2. Agreement between Bloomfield College and the Bloomfield College Chapter of the American Association of University Professors and Bloomfield College Faculty Personnel Procedures, July 1, 1983-June 30, 1985. (United States)

    Bloomfield Coll., NJ.

    The collective bargaining agreement between Bloomfield College and the Bloomfield College Chapter (50 members) of the American Association of University Professors covering the period July 1, 1983-June 30, 1985 is presented. Items covered in the agreement include: contract management, chapter rights, academic freedom, faculty status, terms of…

  3. Isolation and characterization of twelve microsatellite loci for the Japanese Devilray (Mobula japanica)

    NARCIS (Netherlands)

    Poortvliet, Marloes; Galvan-Magana, Felipe; Bernardi, Giacomo; Croll, Donald A.; Olsen, Jeanine L.


    Twelve polymorphic microsatellites loci were characterized for Mobula japanica (Japanese Devilray) using an enrichment protocol. All but two loci were in Hardy-Weinberg equilibrium with no evidence of linkage disequilibrium or null-alleles for a sample of 40 individuals from two populations. The num

  4. 17 CFR 210.3-06 - Financial statements covering a period of nine to twelve months. (United States)


    ... ACT OF 1933, SECURITIES EXCHANGE ACT OF 1934, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935, INVESTMENT COMPANY ACT OF 1940, INVESTMENT ADVISERS ACT OF 1940, AND ENERGY POLICY AND CONSERVATION ACT OF 1975... to twelve months. Except with respect to registered investment companies, the filing of...

  5. Portrayal of Life Form in Selected Biographies for Children Eight to Twelve Years of Age. (United States)

    Koch, Shirley Lois

    This study describes and analyzes, in a critical literary manner, selected biographies for children eight to twelve years of age. Biographies of Jane Addams, Cesar Chavez, Mohandas Gandhi, Toyohiko Kagawa, Martin Luther King, Jr., and Albert Schweitzer are viewed from the perspective of a literary criterion based on the principles of design to…

  6. Premarital sex in the last twelve months and its predictors among ...

    African Journals Online (AJOL)

    Premarital sex in the last twelve months and its predictors among students of ... Statistical significance was determined through a 95% confidence level. ... having comprehensive knowledge of HIV [AOR(95% CI)=1.5(1.01-2.10)], alcohol use ...

  7. Portrayal of Life Form in Selected Biographies for Children Eight to Twelve Years of Age. (United States)

    Koch, Shirley Lois

    This study describes and analyzes, in a critical literary manner, selected biographies for children eight to twelve years of age. Biographies of Jane Addams, Cesar Chavez, Mohandas Gandhi, Toyohiko Kagawa, Martin Luther King, Jr., and Albert Schweitzer are viewed from the perspective of a literary criterion based on the principles of design to…

  8. A novel double quad-inverter configuration for multilevel twelve-phase open-winding converter

    DEFF Research Database (Denmark)

    Padmanaban, Sanjeevi Kumar; Blaabjerg, Frede; Wheeler, Patrick William


    This paper describes a novel proposal of double quad-inverter configuration for multilevel twelve-phase open-winding ac converter. Modular power units are developed from reconfigured eight classical three-phase voltage source inverters (VSIs). Each VSI has one additional bi-directional switching ...

  9. Chapter 6: Prehydrolysis Pulping with Fermentation Coproducts (United States)

    T.H. Wegner; C.J. Houtman; A.W. Rudie; B.L. Illman; P.J. Ince; E.M. Bilek; T.W. Jeffries


    Although the term “integrateed biorefinery” is new, the concept has long been familiar to the pulp and paper industry, where processes include biomass boilers providing combined heat and power, and byproducts of pulping include turpentine, fatty acids and resin acids. In the dominant kraft (or sulfate) pulping process, dissolved lignin and chemicals from the pulp...

  10. Seleucid, Demotic and Mediterranean mathematics versus Chapters VIII and IX of the Nine Chapters: accidental or significant similarities?

    DEFF Research Database (Denmark)

    Høyrup, Jens


    Similarities of geometrical diagrams and arithmetical structures of problems have often been taken as evidence of transmission of mathematical knowledge or techniques between China and “the West”. Confronting on one hand some problems from Chapter VIII of the Nine Chapters with comparable problems...... known from Ancient Greek sources, on the other a Seleucid collection of problems about rectangles with a subset of the triangle problems from Chapter IX, it is concluded, (1) that transmission of some arithmetical riddles without method – not “from Greece” but from a transnational community of traders...

  11. FDA Bacteriological Analytical Manual, Chapter 10, 2003: Listeria monocytogenes (United States)

    FDA Bacteriological Analytical Manual, Chapter 10 describes procedures for analysis of food samples and may be adapted for assessment of solid, particulate, aerosol, liquid and water samples containing Listeria monocytogenes.

  12. Chapter Boundaries, Navajo Nation, 2014, US EPA Region 9 (United States)

    U.S. Environmental Protection Agency — This GIS dataset contains polygon features representing the Chapter Boundaries within Navajo Nation. These administrative boundaries are related to the Navajo Nation...

  13. Chapter 13: Mining electronic health records in the genomics era.

    Directory of Open Access Journals (Sweden)

    Joshua C Denny

    Full Text Available The combination of improved genomic analysis methods, decreasing genotyping costs, and increasing computing resources has led to an explosion of clinical genomic knowledge in the last decade. Similarly, healthcare systems are increasingly adopting robust electronic health record (EHR systems that not only can improve health care, but also contain a vast repository of disease and treatment data that could be mined for genomic research. Indeed, institutions are creating EHR-linked DNA biobanks to enable genomic and pharmacogenomic research, using EHR data for phenotypic information. However, EHRs are designed primarily for clinical care, not research, so reuse of clinical EHR data for research purposes can be challenging. Difficulties in use of EHR data include: data availability, missing data, incorrect data, and vast quantities of unstructured narrative text data. Structured information includes billing codes, most laboratory reports, and other variables such as physiologic measurements and demographic information. Significant information, however, remains locked within EHR narrative text documents, including clinical notes and certain categories of test results, such as pathology and radiology reports. For relatively rare observations, combinations of simple free-text searches and billing codes may prove adequate when followed by manual chart review. However, to extract the large cohorts necessary for genome-wide association studies, natural language processing methods to process narrative text data may be needed. Combinations of structured and unstructured textual data can be mined to generate high-validity collections of cases and controls for a given condition. Once high-quality cases and controls are identified, EHR-derived cases can be used for genomic discovery and validation. Since EHR data includes a broad sampling of clinically-relevant phenotypic information, it may enable multiple genomic investigations upon a single set of genotyped

  14. Qalandar-name. Chapter 1. «Monotheism»

    Directory of Open Access Journals (Sweden)

    Ismagilova M.


    Full Text Available The proposed excerpt of theological work is the translation of the first chapter of «Qalandar-name», supplemented by comments. This is the first edition of chapter from the medieval theological work written in the Golden Horde during the active Islamization of its population, during the times of great Khans – Muhammad Uzbek and Janibek. Its author, Abu Bakr Qalandar, was a native of the city of Aksaray (in modern Turkey, Sufi, great scholar, imam of a mosque in the city of Stary Krym. «Qalandar-name» is an encyclopedic work on Islamic matters and Sufism that begins with a traditional intonation typical for the works of Muslim authors, especially for compilers of theological writings. In this chapter entitled «Tawhid» (monotheism, Abu Bakr Qalandar speaks about beautiful names of the Almighty, about his creative work (comparing it with the jewelry craftsmanship, about heaven and hell, a small (world of sagri and the highest (world of kibriya worlds. D. Shagivaleev who wrote commentaries on the first chapter, supplied the text with verses, to which, according to him, Abu Bakr made allusions. Analysis of the work of Abu Bakr Qalandar reveals that the author of this source was an educated man of his time. In this chapter, Abu Bakr reports about the basic concepts of Islam. The authors plan to publish subsequent chapters of this work in the next issues.

  15. Chapter 19: HVAC Controls (DDC/EMS/BAS) Evaluation Protocol

    Energy Technology Data Exchange (ETDEWEB)

    Romberger, J.


    The HVAC Controls Evaluation Protocol is designed to address evaluation issues for direct digital controls/energy management systems/building automation systems (DDC/EMS/BAS) that are installed to control heating, ventilation, and air-conditioning (HVAC) equipment in commercial and institutional buildings. (This chapter refers to the DDC/EMS/BAS measure as HVAC controls.) This protocol may also be applicable to industrial facilities such as clean rooms and labs, which have either significant HVAC equipment or spaces requiring special environmental conditions. This protocol addresses only HVAC-related equipment and the energy savings estimation methods associated with installing such control systems as an energy efficiency measure. The affected equipment includes: Air-side equipment (air handlers, direct expansion systems, furnaces, other heating- and cooling-related devices, terminal air distribution equipment, and fans); Central plant equipment (chillers, cooling towers, boilers, and pumps). These controls may also operate or affect other end uses, such as lighting, domestic hot water, irrigation systems, and life safety systems such as fire alarms and other security systems. Considerable nonenergy benefits, such as maintenance scheduling, system component troubleshooting, equipment failure alarms, and increased equipment lifetime, may also be associated with these systems. When connected to building utility meters, these systems can also be valuable demand-limiting control tools. However, this protocol does not evaluate any of these additional capabilities and benefits.

  16. Chapter 27 - Ozone layer protection: The unfinished journey

    Energy Technology Data Exchange (ETDEWEB)



    This publication represents Chapter 27 of the Auditor General`s 1997 report to the House of Commons, and is devoted to an assessment of Canada`s performance in meeting international and domestic commitments in reducing ozone depletion in the light of undertakings given by the Government of Canada. While the government was credited with a respectable record of achievements, in some cases even exceeding obligations under the Montreal Protocol, the government also came in for its share of criticism for weak leadership in the fight against ozone depletion, for its failure or tardiness in developing appropriate strategies, for its failure to raise the issue to the level of priority it must have to gain the required public support for the measures necessary to deal with the problem, and for the failure of the government to develop instruments to measure the progress that has been achieved. A thorough revision of the national action plan, a serious attempt at needs assessment, application of science based priority-setting tools and establishing a balance between domestic and international actions were some of the report`s recommendations. A statement of the global ozone depletion scene, and a summary of the Montreal Protocol were also included.

  17. Nutrient Contents per Serving of Twelve Varieties of Cooked Rice Marketed in Jordan

    Directory of Open Access Journals (Sweden)

    Jafar M. El-Qudah


    Full Text Available Jordan imports rice from different countries without any quality preferences. Twelve varieties of cooked rice marketed in Jordan were analyzed. The content per serving of these varieties were computed for energy, protein, carbohydrates, fat, calcium, sodium, potassium, magnesium, manganese, copper, iron and phosphorous. The protein content per serving found to range from 0.49 g for La Cigala rice to 6.2 g for Harvest rice. The fat content for all rice brands was less than 0.37 g per serving. The energy content ranged from 172.12 g/serving for Basmati rice to 212.25 g/serving for Sun White rice. Generally, all rice varieties contain significant amounts of minerals per serving. Ruzzana found to contain the highest level of calcium (38.2 mg/serving and Amber the lowest calcium content (6.7 mg/serving. Magnesium content found to range from 5.7 mg/serving for Royal Umberella rice to 16.3 mg/serving for Ruzzana rice. Consumption of one serving of Harvest cooked rice will cover 13.5% of the daily requirement of protein for females and 11.1% for males. Manganese content of one serving of Harvest, Sun White, Abu bent and La Cigala will cover 22.2% of the daily requirements for females and 14.7% for males, while consumption of one of Basmati, Sos rice or Amber will cover only 11.1% and 8.75 of requirement for females and males respectively. Planning a healthful diet is not a simple task. Dietary Reference Intake planning and assessing the diets of individuals or groups of healthy individuals according to their stage of life and sex. Food choice is a function of many factors, including personal preferences, habits, ethnic heritage and tradition. Dietary guidelines for Americans, consider whole grain products like rice are among the food groups that form the basis of a healthy diet. Including rice as part of a healthy, balanced diet can be linked to overall healthier eating patterns. Rice eaters are more likely to eat a diet consistent with the 2005 Dietary

  18. Experiencing a constructivist museum exhibit: A case study of twelve children and their families (United States)

    Hill, Martha Anne Leech


    The American Association for the Advancement of Science and the National Research Council have called for the creation of a scientifically literate populace and introduced science standards and guidelines to direct this process. Science education in traditional school settings plays a key role in reaching this goal, but individuals over their lifetimes will have more exposure to science ideas through informal science experiences such as visits to museums and through diverse media sources. The purpose of this study was to explore the role museums play in this journey to science literacy. This qualitative collective case study examined the experience of 12 children and their families in a children's museum as they interacted with an exhibit designed along the tenets of constructivist theory to introduce children to ideas of science. Twelve children and their families were videotaped interacting with a model of a watershed that included the stream, surrounding land, gravel, and dam building and erosion abatement manipulatives. Children were interviewed to ascertain their stream-related ideas and conceptual understanding prior to and after using the exhibit. Parents completed demographic and post-exhibit experience questionnaires. Two museum staff members who played key roles in the development of the exhibit and surrounding gallery were also interviewed. Individual and cross-case analyses were done to describe the experience of each child and family, and to elucidate the commonalities of these experiences to describe the phenomenon of using a constructivist-based science exhibit. Results of the study indicate (1) the type of experience children and families had at the exhibit depended on child and parent interactions and roles each assumed, and (2) experience with the exhibit encouraged children to think more deeply about water topics, past experiences, and ideas they had previously constructed. Implications of this research include (1) parents should engage children

  19. Southern Nevada ecosystem stressors [Chapter 2 (United States)

    Burton K. Pendleton; Jeanne C. Chambers; Mathew L. Brooks; Steven M. Ostoja


    Southern Nevada ecosystems and their associated resources are subject to a number of global and regional/local stressors that are affecting the sustainability of the region. Global stressors include elevated carbon dioxide (CO2) concentrations and associated changes in temperature and precipitation patterns and amounts, solar radiation, and nutrient cycles (Smith and...

  20. Anatomical studies on twelve clones of Camellia species with reference to their taxonomic significance

    Directory of Open Access Journals (Sweden)

    Rajanna L


    Full Text Available Anatomical studies of leaf and stem of twelve clones of Camellia were investigated. Cross sections of the stem of all the clones exhibited a typical pattern of arrangement of tissues characteristics of woody plants. Two types of idioblastic sclereids were found in the medullary parenchyma of the taxa studied. While astrosclereids werepresent in 10 of the twelve clones, the vesciculose sclereids were found only in the four clones belonging to C. sinensis. Leaves of the clones show variations in the number of palisade layers. Astro sclereids, brachy sclereids, and dendritic forms were observed in the leaves, their distribution varying in the different clones. A few other micromorphological features are also recorded. Our study forms a basis for answering uncertainties in taxonomic revision in the genus Camellia.

  1. Risk factors for chronic noncontiguous diseases: Twelve-week prospective study

    Directory of Open Access Journals (Sweden)

    Lapčević Mirjana


    Full Text Available Risk factors (RF of chronic noncontiguous diseases (CND are mutual and cannot be observed individually since there is an inter-reaction (interaction of RF in various combinations, what makes so-called personality risk profile for development of particular disease. Almost all CND belong to the group of preventable diseases, because their course may be influenced and changed through RF modification and reduction. Bad habits also contribute to CND incidence. CND prevention is the first priority of primary health care physicians. The main objective of our study was to detect RF in patients during everyday activities of general practitioner, to estimate the risk of CND within the existing RF combination, to show the results of 12-week active monitoring of population with RF of CND, and with already present CND; while the secondary goal was to assess how much population is interested in active collaboration as well as to evaluate the qualification of general medicine teams for work based on defined methodology. The study was multicentric, prospective and interventional. The study included 2086 subjects, aged from 25-64 years, and it was carried out in 17 health centers throughout Serbia in the period January-April 2002. The subjects were selected by method of open clinical experiment. Thereafter, 12-week medical intervention was initiated involving non-pharmacological and pharmacological treatment. The first control was scheduled after 8, and the second after 12 months of intervention. Congruence χ2 test, ANOVA for repeated measurements and Logistic regression were used for statistical data processing. Out of a total of 2086 subjects, the following proportion of them reported specific diagnosis in their medical histories: 77% of them reported arterial hypertension (HTA, 68% - increased body mass (BMI>27Kg/m2, 66% - hyperlipoproteinemia (HLP, 34% - diabetes mellitus (DM, 56% - inadequate physical activity (PA, and 23% - cigarette smoking (CS. On the

  2. [Risk factors for chronic noncontiguous diseases: twelve-week prospective study]. (United States)

    Lapcević, Mirjana; Vuković, Mira


    Risk factors (RF) of chronic noncontiguous diseases (CND) are mutual and cannot be observed individually since there is an inter-reaction (interaction of RF in various combinations), what makes so-called personality risk profile for development of particular disease. Almost all CND belong to the group of preventable diseases, because their course may be influenced and changed through RF modification and reduction. Bad habits also contribute to CND incidence. CND prevention is the first priority of primary health care physicians. The main objective of our study was to detect RF in patients during everyday activities of general practitioner, to estimate the risk of CND within the existing RF combination, to show the results of 12-week active monitoring of population with RF of CND, and with already present CND; while the secondary goal was to assess how much population is interested in active collaboration as well as to evaluate the qualification of general medicine teams for work based on defined methodology. The study was multicentric, prospective and interventional. The study included 2086 subjects, aged from 25-64 years, and it was carried out in 17 health centers throughout Serbia in the period January-April 2002. The subjects were selected by method of open clinical experiment. Thereafter, 12-week medical intervention was initiated involving non-pharmacological and pharmacological treatment. The first control was scheduled after 8, and the second after 12 months of intervention. Congruence chi2 test, ANOVA for repeated measurements and Logistic regression were used for statistical data processing. Out of a total of 2086 subjects, the following proportion of them reported specific diagnosis in their medical histories: 77% of them reported arterial hypertension (HTA), 68%--increased body mass (BMI > or = 27Kg/m2), 66%--hyperlipoproteinemia (HLP), 34%--diabetes mellitus (DM), 56%--inadequate physical activity (PA), and 23%--cigarette smoking (CS). On the basis of

  3. Planning the Future of U.S. Particle Physics (Snowmass 2013): Chapter 3: Energy Frontier

    CERN Document Server

    Brock, R; Agashe, K; Artuso, M; Campbell, J; Dawson, S; Erbacher, R; Gerber, C; Gershtein, Y; Gritsan, A; Hatakeyama, K; Huston, J; Kotwal, A; Logan, H; Luty, M; Melnikov, K; Narain, M; Papucci, M; Petriello, F; Prell, S; Qian, J; Schwienhorst, R; Tully, C; Van Kooten, R; Wackeroth, D; Wang, L; Whiteson, D


    These reports present the results of the 2013 Community Summer Study of the APS Division of Particles and Fields ("Snowmass 2013") on the future program of particle physics in the U.S. Chapter 3, on the Energy Frontier, discusses the program of research with high-energy colliders. This area includes experiments on the Higgs boson, the electroweak and strong interactions, and the top quark. It also encompasses direct searches for new particles and interactions at high energy.

  4. Planning the Future of U.S. Particle Physics (Snowmass 2013): Chapter 3: Energy Frontier

    Energy Technology Data Exchange (ETDEWEB)

    Brock, R.; et al.


    These reports present the results of the 2013 Community Summer Study of the APS Division of Particles and Fields ("Snowmass 2013") on the future program of particle physics in the U.S. Chapter 3, on the Energy Frontier, discusses the program of research with high-energy colliders. This area includes experiments on the Higgs boson, the electroweak and strong interactions, and the top quark. It also encompasses direct searches for new particles and interactions at high energy.

  5. Chapter Green Nanotechnology: Development of Nanomaterials for Environmental and Energy Applications


    Fagan, Rachel; Han, Changseok; Andersen, Joel; Pillai, Suresh; Falaras, Polycarpos; Byrne, Anthony; Dunlop, Patrick S. M.; Choi, Hyeok; Jiang, Wenjun; O’Shea, Kevin; Dionysiou, Dionysios D.


    This book chapter discusses the syntheses of various nanomaterials, for green nanotechnology applications in detail. Special attention is given to the development of emerging areas, such as environmental as well as energy materials. Various approaches for preparing nanostructured photocatalysts, such as titanium dioxide, zinc oxide, iron oxide, and metal sulfides, different conventional methods and novel methods, including sol-gel methods, hydrothermal methods, microwave-assisted methods and ...

  6. Planning the Future of U.S. Particle Physics (Snowmass 2013): Chapter 2: Intensity Frontier

    CERN Document Server

    Hewett, J L; Babu, K S; Butler, J; Casey, B; de Gouvea, A; Essig, R; Grossman, Y; Hitlin, D; Jaros, J; Kearns, E; Kumar, K; Ligeti, Z; Lu, Z -T; Pitts, K; Ramsey-Musolf, M; Ritchie, J; Scholberg, K; Wester, W; Zeller, G P


    These reports present the results of the 2013 Community Summer Study of the APS Division of Particles and Fields ("Snowmass 2013") on the future program of particle physics in the U.S. Chapter 2, on the Intensity Frontier, discusses the program of research with high-intensity beams and rare processes. This area includes experiments on neutrinos, proton decay, charged-lepton and quark weak interactions, atomic and nuclear probes of fundamental symmetries, and searches for new, light, weakly-interacting particles.

  7. Planning the Future of U.S. Particle Physics (Snowmass 2013): Chapter 4: Cosmic Frontier

    Energy Technology Data Exchange (ETDEWEB)

    Feng, J. L. [MIT, LNS; Ritz, S. [UC, Santa Cruz; Beatty, J. J. [Ohio State U.; Buckley, J. [Washington U., Seattle; Cowen, D. F. [Penn State U.; Cushman, P. [Minnesota U.; Dodelson, S. [Chicago U., Astron. Astrophys. Ctr.; Galbiati, C. [PNPI, CSTD; Honscheid, K. [Ohio State U.; Hooper, D. [Chicago U., Astron. Astrophys. Ctr.; Kaplinghat, M. [UC, Irvine; Kusenko, A. [Unlisted; Matchev, K. [Florida U.; McKinsey, D. [Yale U.; Nelson, A. E. [Washington U., Seattle; Olinto, A. [Chicago U., EFI; Profumo, S. [UC, Santa Cruz; Robertson, H. [Washington U., Seattle; Rosenberg, L. [Unlisted; Sinnis, G. [Los Alamos; Tait, T. M.P. [UCLA


    These reports present the results of the 2013 Community Summer Study of the APS Division of Particles and Fields ("Snowmass 2013") on the future program of particle physics in the U.S. Chapter 4, on the Cosmic Frontier, discusses the program of research relevant to cosmology and the early universe. This area includes the study of dark matter and the search for its particle nature, the study of dark energy and inflation, and cosmic probes of fundamental symmetries.

  8. Volcanism on the Red Planet: Mars. Chapter 4 (United States)

    Greeley, Ronald; Bridges, Nathan T.; Crown, David A.; Crumpler, Larry S.; Fagents, Sarah A.; Mouginis-Mark, Peter J.; Zimbelman, James R.


    Of all the planets in the Solar System, Mars is the most Earthlike in its geological characteristics. Like Earth, it has been subjected to exogenic processes, such as impact cratesing and erosion by wind and water, as well as endogenic processes, including tectonic deformation of the crust and volcanism. The effects of these processes are amply demonstrated by the great variety of surface features, including impact craters, landslides, former river channels, sand dunes, and the largest volcanoes in the Solar System. Some of these features suggest substantial changes in Mars' environment during its history. For example, as reviewed by Carr, today Mars is a cold, dry desert with an average atmospheric pressure of only 5.6 mbar which does not allow liquid water to exist on the surface. To some planetary scientists, the presence of the channels bespeaks a time when Mars was warmer and wetter. However, others have argued that these features might have formed under current conditions and that there might not have been a shift in climate. Could the morphology of volcanoes and related features provide clues to past Martian environments? What role is played by atmospheric density in the styles of eruptions on Mars and resulting landforms? If these and related questions can be answered, then we may have a means for assessing the conditions on Mars' surface in the past and comparing the results with models of Martian evolution. In this chapter, we outline the sources of information available for volcanism on Mars, explore the influence of the Martian environment on volcanic processes, and describe the principal volcanic features and their implications for understanding the general evolution of the Martian surface.

  9. Volcanism on the Red Planet: Mars. Chapter 4 (United States)

    Greeley, Ronald; Bridges, Nathan T.; Crown, David A.; Crumpler, Larry S.; Fagents, Sarah A.; Mouginis-Mark, Peter J.; Zimbelman, James R.


    Of all the planets in the Solar System, Mars is the most Earthlike in its geological characteristics. Like Earth, it has been subjected to exogenic processes, such as impact cratesing and erosion by wind and water, as well as endogenic processes, including tectonic deformation of the crust and volcanism. The effects of these processes are amply demonstrated by the great variety of surface features, including impact craters, landslides, former river channels, sand dunes, and the largest volcanoes in the Solar System. Some of these features suggest substantial changes in Mars' environment during its history. For example, as reviewed by Carr, today Mars is a cold, dry desert with an average atmospheric pressure of only 5.6 mbar which does not allow liquid water to exist on the surface. To some planetary scientists, the presence of the channels bespeaks a time when Mars was warmer and wetter. However, others have argued that these features might have formed under current conditions and that there might not have been a shift in climate. Could the morphology of volcanoes and related features provide clues to past Martian environments? What role is played by atmospheric density in the styles of eruptions on Mars and resulting landforms? If these and related questions can be answered, then we may have a means for assessing the conditions on Mars' surface in the past and comparing the results with models of Martian evolution. In this chapter, we outline the sources of information available for volcanism on Mars, explore the influence of the Martian environment on volcanic processes, and describe the principal volcanic features and their implications for understanding the general evolution of the Martian surface.

  10. Visual And Performing Arts Framework For California Public Schools: Kindergarten through Grade Twelve (United States)

    California State Department of Education, 2004


    This framework is designed to help classroom teachers and other educators develop curriculum and instruction in the arts so that all students will meet or exceed the content standards in dance, music, theatre, and the visual arts. In chapter 1, the framework presents guiding principles for instruction in dance, music, theatre, and the visual arts.…

  11. Descriptions of twelve new species of ochyroceratids (Araneae, Ochyroceratidae) from mainland Ecuador. (United States)

    Dupérré, Nadine


    Twelve new species in three different genera from the spider family Ochyroceratidae are described from mainland Ecuador: Speocera bioforestae sp. n., Speocera violacea sp. n., Speocera musgo sp. n., Ochyrocera rinocerotos sp. n., Ochyrocera callaina sp. n., Ochyrocera italoi sp. n., Ochyrocera minotaure sp. n., Ochyrocera losrios sp. n., Ochyrocera zabaleta sp. n., Ochyrocera otonga sp. n., Ochyrocera cashcatotoras sp. n. and Psiloochyrocera tortilis sp. n. Speocera machadoi Gertsch 1977 is transferred to Ochyrocera.

  12. A Hidden Twelve-Dimensional SuperPoincare Symmetry In Eleven Dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Bars, Itzhak; Deliduman, Cemsinan; Pasqua, Andrea; Zumino, Bruno


    First, we review a result in our previous paper, of how a ten-dimensional superparticle, taken off-shell, has a hidden eleven-dimensional superPoincare symmetry. Then, we show that the physical sector is defined by three first-class constraints which preserve the full eleven-dimensional symmetry. Applying the same concepts to the eleven dimensional superparticle, taken off-shell, we discover a hidden twelve dimensional superPoincare symmetry that governs the theory.

  13. Hidden twelve-dimensional super Poincaré symmetry in eleven dimensions

    CERN Document Server

    Bars, Itzhak; Pasqua, A; Zumino, B; Bars, Itzhak; Deliduman, Cemsinan; Pasqua, Andrea; Zumino, Bruno


    First, we review a result in our previous paper, of how a ten-dimensional superparticle, taken off-shell, has a hidden eleven-dimensional superPoincare symmetry. Then, we show that the physical sector is defined by three first-class constraints which preserve the full eleven-dimensional symmetry. Applying the same concepts to the eleven dimensional superparticle, taken off-shell, we discover a hidden twelve dimensional superPoincare symmetry that governs the theory.

  14. Optical modulator including grapene

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Ming; Yin, Xiaobo; Zhang, Xiang


    The present invention provides for a one or more layer graphene optical modulator. In a first exemplary embodiment the optical modulator includes an optical waveguide, a nanoscale oxide spacer adjacent to a working region of the waveguide, and a monolayer graphene sheet adjacent to the spacer. In a second exemplary embodiment, the optical modulator includes at least one pair of active media, where the pair includes an oxide spacer, a first monolayer graphene sheet adjacent to a first side of the spacer, and a second monolayer graphene sheet adjacent to a second side of the spacer, and at least one optical waveguide adjacent to the pair.

  15. Chapter 18: Variable Frequency Drive Evaluation Protocol

    Energy Technology Data Exchange (ETDEWEB)

    Romberger, J.


    An adjustable-speed drive (ASD) includes all devices that vary the speed of a rotating load, including those that vary the motor speed and linkage devices that allow constant motor speed while varying the load speed. The Variable Frequency Drive Evaluation Protocol presented here addresses evaluation issues for variable-frequency drives (VFDs) installed on commercial and industrial motor-driven centrifugal fans and pumps for which torque varies with speed. Constant torque load applications, such as those for positive displacement pumps, are not covered by this protocol. Other ASD devices, such as magnetic drive, eddy current drives, variable belt sheave drives, or direct current motor variable voltage drives, are also not addressed. The VFD is by far the most common type of ASD hardware. With VFD speed control on a centrifugal fan or pump motor, energy use follows the affinity laws, which state that the motor electricity demand is a cubic relationship to speed under ideal conditions. Therefore, if the motor runs at 75% speed, the motor demand will ideally be reduced to 42% of full load power; however, with other losses it is about 49% of full load power.

  16. Chapter 17: bioimage informatics for systems pharmacology.

    Directory of Open Access Journals (Sweden)

    Fuhai Li


    Full Text Available Recent advances in automated high-resolution fluorescence microscopy and robotic handling have made the systematic and cost effective study of diverse morphological changes within a large population of cells possible under a variety of perturbations, e.g., drugs, compounds, metal catalysts, RNA interference (RNAi. Cell population-based studies deviate from conventional microscopy studies on a few cells, and could provide stronger statistical power for drawing experimental observations and conclusions. However, it is challenging to manually extract and quantify phenotypic changes from the large amounts of complex image data generated. Thus, bioimage informatics approaches are needed to rapidly and objectively quantify and analyze the image data. This paper provides an overview of the bioimage informatics challenges and approaches in image-based studies for drug and target discovery. The concepts and capabilities of image-based screening are first illustrated by a few practical examples investigating different kinds of phenotypic changes caEditorsused by drugs, compounds, or RNAi. The bioimage analysis approaches, including object detection, segmentation, and tracking, are then described. Subsequently, the quantitative features, phenotype identification, and multidimensional profile analysis for profiling the effects of drugs and targets are summarized. Moreover, a number of publicly available software packages for bioimage informatics are listed for further reference. It is expected that this review will help readers, including those without bioimage informatics expertise, understand the capabilities, approaches, and tools of bioimage informatics and apply them to advance their own studies.

  17. Chapter 16: text mining for translational bioinformatics.

    Directory of Open Access Journals (Sweden)

    K Bretonnel Cohen


    Full Text Available Text mining for translational bioinformatics is a new field with tremendous research potential. It is a subfield of biomedical natural language processing that concerns itself directly with the problem of relating basic biomedical research to clinical practice, and vice versa. Applications of text mining fall both into the category of T1 translational research-translating basic science results into new interventions-and T2 translational research, or translational research for public health. Potential use cases include better phenotyping of research subjects, and pharmacogenomic research. A variety of methods for evaluating text mining applications exist, including corpora, structured test suites, and post hoc judging. Two basic principles of linguistic structure are relevant for building text mining applications. One is that linguistic structure consists of multiple levels. The other is that every level of linguistic structure is characterized by ambiguity. There are two basic approaches to text mining: rule-based, also known as knowledge-based; and machine-learning-based, also known as statistical. Many systems are hybrids of the two approaches. Shared tasks have had a strong effect on the direction of the field. Like all translational bioinformatics software, text mining software for translational bioinformatics can be considered health-critical and should be subject to the strictest standards of quality assurance and software testing.

  18. Chapter 1: Sinonasal anatomy and function. (United States)

    Dalgorf, Dustin M; Harvey, Richard J


    An understanding of paranasal sinus anatomy based on important fixed landmarks rather than variable anatomy is critical to ensure safe and complete surgery. The concept of the paranasal surgical box defines the anatomic limits of dissection. The boundaries of the surgical box include the middle turbinate medially, orbital wall laterally, and skull base superiorly. The "vertical component" of the surgical box defines the boundaries of the frontal recess and includes the middle turbinate and intersinus septum medially, medial orbital wall and orbital roof laterally, nasofrontal beak anteriorly, and skull base and posterior table of frontal sinus posteriorly. The paranasal sinuses are divided into anterior, posterior, and sphenoidal functional cavities based on their distinct drainage pathways into the nose. The ultimate goal of surgery is to create a functional sinus cavity. Application of the paranasal surgical box and its vertical component enables the surgeon to view the limits of dissection with a single position of the endoscope. This will ensure complete dissection of the functional sinonasal compartments and effectively avoid leaving behind disconnected cells from the surgical cavity, mucocele formation, mucous recirculation, overcome obstructive phenomenon and enable maximal delivery of topical therapy in the post-operative setting. This article reviews the structure and function of the nasal cartilages and turbinates. It also describes the concept of the paranasal surgical box, key anatomical landmarks and limits of dissection. Normal anatomy and common variants of normal anatomy are discussed.

  19. Chapter 16: text mining for translational bioinformatics. (United States)

    Cohen, K Bretonnel; Hunter, Lawrence E


    Text mining for translational bioinformatics is a new field with tremendous research potential. It is a subfield of biomedical natural language processing that concerns itself directly with the problem of relating basic biomedical research to clinical practice, and vice versa. Applications of text mining fall both into the category of T1 translational research-translating basic science results into new interventions-and T2 translational research, or translational research for public health. Potential use cases include better phenotyping of research subjects, and pharmacogenomic research. A variety of methods for evaluating text mining applications exist, including corpora, structured test suites, and post hoc judging. Two basic principles of linguistic structure are relevant for building text mining applications. One is that linguistic structure consists of multiple levels. The other is that every level of linguistic structure is characterized by ambiguity. There are two basic approaches to text mining: rule-based, also known as knowledge-based; and machine-learning-based, also known as statistical. Many systems are hybrids of the two approaches. Shared tasks have had a strong effect on the direction of the field. Like all translational bioinformatics software, text mining software for translational bioinformatics can be considered health-critical and should be subject to the strictest standards of quality assurance and software testing.

  20. Visual Impairment, Including Blindness (United States)

    ... Who Knows What? Survey Item Bank Search for: Visual Impairment, Including Blindness Links updated, April 2017 En ... doesn’t wear his glasses. Back to top Visual Impairments in Children Vision is one of our ...

  1. Biodiversity loss and infectious diseases: chapter 5 (United States)

    Lafferty, Kevin D.


    When conservation biologists think about infectious diseases, their thoughts are mostly negative. Infectious diseases have been associated with the extinction and endangerment of some species, though this is rare, and other factors like habitat loss and poorly regulated harvest still are the overwhelming drivers of endangerment. Parasites are pervasive and play important roles as natural enemies on par with top predators, from regulating population abundances to maintaining species diversity. Sometimes, parasites themselves can be endangered. However, it seems unlikely that humans will miss extinct parasites. Parasites are often sensitive to habitat loss and degradation, making them positive indicators of ecosystem “health”. Conservation biologists need to carefully consider infectious diseases when planning conservation actions. This can include minimizing the movement of domestic and invasive species, vaccination, and culling.

  2. Chapter 8. Black Holes in Braneworld Models (United States)

    Tanahashi, N.; Tanaka, T.

    In this review, we summarize current understandings of blackhole solutions in various braneworld models, including the Arkani-Hamed-Dimopoulos-Dvali model, the Randall-Sundrum (RS) models, Karch-Randall (KR) model and the Dvali-Gabadadze-Porrati model. After illustrating basic properties of each braneworld model, we introduce the bulk/brane correspondence in the RS and KR braneworld models, adding supporting evidence for it. We then summarize the studies on braneworld black hole solutions, which consist of constructing exact or approximate solutions and investigating the phase diagram of solutions. In the study of phase diagram, we will also expound the implications of the bulk/brane correspondence to the braneworld black holes.

  3. Intelligent Control and Health Monitoring. Chapter 3 (United States)

    Garg, Sanjay; Kumar, Aditya; Mathews, H. Kirk; Rosenfeld, Taylor; Rybarik, Pavol; Viassolo, Daniel E.


    Advanced model-based control architecture overcomes the limitations state-of-the-art engine control and provides the potential of virtual sensors, for example for thrust and stall margin. "Tracking filters" are used to adapt the control parameters to actual conditions and to individual engines. For health monitoring standalone monitoring units will be used for on-board analysis to determine the general engine health and detect and isolate sudden faults. Adaptive models open up the possibility of adapting the control logic to maintain desired performance in the presence of engine degradation or to accommodate any faults. Improved and new sensors are required to allow sensing at stations within the engine gas path that are currently not instrumented due in part to the harsh conditions including high operating temperatures and to allow additional monitoring of vibration, mass flows and energy properties, exhaust gas composition, and gas path debris. The environmental and performance requirements for these sensors are summarized.

  4. Chapter 22: Compressed Air Evaluation Protocol

    Energy Technology Data Exchange (ETDEWEB)

    Benton, N.


    Compressed-air systems are used widely throughout industry for many operations, including pneumatic tools, packaging and automation equipment, conveyors, and other industrial process operations. Compressed-air systems are defined as a group of subsystems composed of air compressors, air treatment equipment, controls, piping, pneumatic tools, pneumatically powered machinery, and process applications using compressed air. A compressed-air system has three primary functional subsystems: supply, distribution, and demand. Air compressors are the primary energy consumers in a compressed-air system and are the primary focus of this protocol. The two compressed-air energy efficiency measures specifically addressed in this protocol are: high-efficiency/variable speed drive (VSD) compressor replacing modulating compressor; compressed-air leak survey and repairs. This protocol provides direction on how to reliably verify savings from these two measures using a consistent approach for each.

  5. Chapter 15: Commercial New Construction Protocol

    Energy Technology Data Exchange (ETDEWEB)

    Keates, S.


    This protocol is intended to describe the recommended method when evaluating the whole-building performance of new construction projects in the commercial sector. The protocol focuses on energy conservation measures (ECMs) measures (or packages of measures) where evaluators can best analyze impacts using building simulation. These ECMs typically require the use of calibrated building simulations under Option D of the International Performance Measurement and Verification Protocol. Examples of such measures include Leadership in Energy and Environmental Design building certification, novel and/or efficient heating, ventilation, and air conditioning system designs, and extensive building controls systems. In general, it is best to evaluate any ECM (or set of measures) expected to significantly interact with other systems within the building and with savings sensitive to seasonal variations in weather.

  6. Mineral Nutrition of Plants. Chapter 9 (United States)

    Wignarajah, Kanapathipillai


    The ultimate source of nutrients for all living organisms consists of the inanimate nutrient reserves found on earth. Of the elements known to exist, seven are considered essential to plants in large amounts (macronutrients), and many others are required in smaller quantities (micronutrients). Essentiality of a nutrient is defined according to the following concepts: (a) A deficiency of the element makes it impossible for the plant to complete the vegetative or reproductive stage of its cycle; (b) such deficiency is specific to the element in question and can be prevented or corrected only by supplying this element; (c) the element is directly involved in the nutrition of the plant quite apart from its possible effects in correcting some unfavorable microbiological or chemical condition of the soil or other culture medium. From that standpoint a favorable response from adding a given element to the culture medium does not constitute conclusive evidence of its indispensability in plant nutrition. All the elements occurring in the outer part of the earth are in constant turnover among the different components of earth. This overall migration is referred to as geochemical cycling. When cycling includes a role for biological organisms, it is referred to as "biogeochemical cycling." Like most cyclical processes in nature, the biogeochemical cycling of elements is not continuous, nor does it proceed in a well-defined direction. At stages, it may be halted or short-circuited, or it may change. Any changes will eventually impact the survival, evolution, and development of biological species in the system. The relationship of the various systems is represented in a schematic manner. To assess the efficiency of operation of the biogeochemical cycles, it is important to include both natural and human activities. Often reliable values on use by man are difficult to obtain for a number of reasons, such as lack of international cooperation, and lack of proper bookkeeping and

  7. Smolt physiology and endocrinology: Chapter 5 (United States)

    McCormick, Stephen D.; McCormick, Stephen D.; Farrell, Anthony Peter; Brauner, Colin J.


    The parr-smolt transformation of anadromous salmonids is a suite of behavioral, morphological, and physiological changes that are preparatory for downstream migration and seawater entry. The timing of smolt development varies among species, occurring soon after hatching in pink and chum salmon and after one to several years in Atlantic salmon. In many species the transformation is size dependent and occurs in spring, mediated through photoperiod and temperature cues. Smolt development is stimulated by several hormones including growth hormone, insulin-like growth factor-1, cortisol, and thyroid hormones, whereas prolactin is generally inhibitory. Increased salinity tolerance is one of the most important and tractable changes, and is caused by alteration in the function of the major osmoregulatory organs, the gill, gut, and kidney. Increased abundance of specific ion transporters (Na+/K+-ATPase, Na+/K+/Cl− cotransporter and apical Cl− channel) in gill ionocytes results in increased salt secretory capacity, increased growth and swimming performance in seawater, and higher marine survival.

  8. Chapter 8: Biological knowledge assembly and interpretation.

    Directory of Open Access Journals (Sweden)

    Ju Han Kim

    Full Text Available Most methods for large-scale gene expression microarray and RNA-Seq data analysis are designed to determine the lists of genes or gene products that show distinct patterns and/or significant differences. The most challenging and rate-liming step, however, is to determine what the resulting lists of genes and/or transcripts biologically mean. Biomedical ontology and pathway-based functional enrichment analysis is widely used to interpret the functional role of tightly correlated or differentially expressed genes. The groups of genes are assigned to the associated biological annotations using Gene Ontology terms or biological pathways and then tested if they are significantly enriched with the corresponding annotations. Unlike previous approaches, Gene Set Enrichment Analysis takes quite the reverse approach by using pre-defined gene sets. Differential co-expression analysis determines the degree of co-expression difference of paired gene sets across different conditions. Outcomes in DNA microarray and RNA-Seq data can be transformed into the graphical structure that represents biological semantics. A number of biomedical annotation and external repositories including clinical resources can be systematically integrated by biological semantics within the framework of concept lattice analysis. This array of methods for biological knowledge assembly and interpretation has been developed during the past decade and clearly improved our biological understanding of large-scale genomic data from the high-throughput technologies.

  9. Chapter 22: Hereditary and acquired angioedema. (United States)

    Georgy, Mary S; Pongracic, Jacqueline A


    Hereditary angioedema (HAE) is an autosomal dominant disorder defined by a deficiency of functional C1 esterase inhibitor (C1-INH). Acquired angioedema (AAE) is caused by either consumption (type 1) or inactivation (type 2) of CI-INH. Both HAE and AAE can be life-threatening. The screening test for both conditions is complement component C4, which is low to absent at times of angioedema or during quiescent periods. A useful test to differentiate HAE from AAE is C1q protein, which is normal in HAE and low in AAE. There are three types of HAE: type 1 HAE is most common, occurring in ∼85% of patients and characterized by decreased production of C1-INH, resulting in reduced functional activity to 5-30% of normal. In type 2, which occurs in 15% of cases, C1-INH is detectable in normal or elevated quantities but is dysfunctional. Finally, type 3, which is rare and almost exclusively occurs in women, is estrogen dependent and associated with normal CI-INH and C4 levels. One-third of these patients have a gain-of-function mutation in clotting factor XII leading to kallikrein-driven bradykinin production. Although the anabolic steroid, danazol, is useful in increasing the concentration of C4 and reducing the episodes of angioedema in HAE and AAE, it has expected adverse effects. Fortunately, disease-specific therapies are available and include C1-INH enzyme for i.v. infusion either acutely or empirically, ecallantide, an inhibitor of kallikrein, and icatibant, a bradykinin B2-receptor antagonist, both approved for acute angioedema and administered, subcutaneously.

  10. Chapter 27: Approach to primary immunodeficiency. (United States)

    Uzzaman, Ashraf; Fuleihan, Ramsay L


    Primary immunodeficiency diseases (PID) are inherited defects of the innate or adaptive arms of the immune system that lead to an increase in the incidence, frequency, or severity of infections. There may be defects in the adaptive arm of the immune system that include combined immunodeficiency and antibody deficiency syndromes or by abnormalities in innate immunity such as disorders of phagocytes, the complement pathway, or Toll-Like receptor (TLR) mediated signaling. Recurrent sinopulmonary infections with encapsulated bacteria such as Haemophilus influenza type B or Streptococcus pneumoniae may be characteristic of an IgG antibody deficiency or dysfunction. Frequent viral, fungal, or protozoal infections may suggest T lymphocyte dysfunction. Multiple staphylococcal skin infections and fungal infections may imply neutrophil dysfunction or the hyper-IgE syndrome, and recurrent neisserial infection is a characteristic manifestation of late complement component (C5-9, or the membrane attack complex) defects. Recurrent viral or pyogenic bacterial infections often without the presence of a significant inflammatory response suggest a defect in TLR signaling. Mycobacterial infections are characteristic of defects in interleukin (IL)-12, interferon (IFN) gamma, or their receptors. Screening of newborns for T-cell lymphopenia using a polymerase chain reaction to amplify T-cell receptor excision circles (TRECs), which are formed when a T cell rearranges the variable region of its receptor, serves as a surrogate for newly synthesized naïve T cells. Because of very low numbers of TRECs, severe combined immunodeficiency, DiGeorge syndrome, and other causes of T-cell lymphopenia have been identified in newborns.

  11. Chapter 11. Community analysis-based methods

    Energy Technology Data Exchange (ETDEWEB)

    Cao, Y.; Wu, C.H.; Andersen, G.L.; Holden, P.A.


    Microbial communities are each a composite of populations whose presence and relative abundance in water or other environmental samples are a direct manifestation of environmental conditions, including the introduction of microbe-rich fecal material and factors promoting persistence of the microbes therein. As shown by culture-independent methods, different animal-host fecal microbial communities appear distinctive, suggesting that their community profiles can be used to differentiate fecal samples and to potentially reveal the presence of host fecal material in environmental waters. Cross-comparisons of microbial communities from different hosts also reveal relative abundances of genetic groups that can be used to distinguish sources. In increasing order of their information richness, several community analysis methods hold promise for MST applications: phospholipid fatty acid (PLFA) analysis, denaturing gradient gel electrophoresis (DGGE), terminal restriction fragment length polymorphism (TRFLP), cloning/sequencing, and PhyloChip. Specific case studies involving TRFLP and PhyloChip approaches demonstrate the ability of community-based analyses of contaminated waters to confirm a diagnosis of water quality based on host-specific marker(s). The success of community-based MST for comprehensively confirming fecal sources relies extensively upon using appropriate multivariate statistical approaches. While community-based MST is still under evaluation and development as a primary diagnostic tool, results presented herein demonstrate its promise. Coupled with its inherently comprehensive ability to capture an unprecedented amount of microbiological data that is relevant to water quality, the tools for microbial community analysis are increasingly accessible, and community-based approaches have unparalleled potential for translation into rapid, perhaps real-time, monitoring platforms.

  12. Chapter L: U.S. Industrial Garnet (United States)

    Evans, James G.; Moyle, Phillip R.


    The United States presently consumes about 16 percent of global production of industrial garnet for use in abrasive airblasting, abrasive coatings, filtration media, waterjet cutting, and grinding. As of 2005, domestic garnet production has decreased from a high of 74,000 t in 1998, and imports have increased to the extent that as much as 60 percent of the garnet used in the United States in 2003 was imported, mainly from India, China, and Australia; Canada joined the list of suppliers in 2005. The principal type of garnet used is almandite (almandine), because of its specific gravity and hardness; andradite is also extensively used, although it is not as hard or dense as almandite. Most industrial-grade garnet is obtained from gneiss, amphibolite, schist, skarn, and igneous rocks and from alluvium derived from weathering and erosion of these rocks. Garnet mines and occurrences are located in 21 States, but the only presently active (2006) mines are in northern Idaho (garnet placers; one mine), southeastern Montana (garnet placers; one mine), and eastern New York (unweathered bedrock; two mines). In Idaho, garnet is mined from Tertiary and (or) Quaternary sedimentary deposits adjacent to garnetiferous metapelites that are correlated with the Wallace Formation of the Proterozoic Belt Supergroup. In New York, garnet is mined from crystalline rocks of the Adirondack Mountains that are part of the Proterozoic Grenville province, and from the southern Taconic Range that is part of the northern Appalachian Mountains. In Montana, sources of garnet in placers include amphibolite, mica schist, and gneiss of Archean age and younger granite. Two mines that were active in the recent past in southwestern Montana produced garnet from gold dredge tailings and saprolite. In this report, we review the history of garnet mining and production and describe some garnet occurrences in most of the Eastern States along the Appalachian Mountains and in some of the Western States where

  13. Ultra pressure liquid chromatography-negative electrospray ionization mass spectrometry determination of twelve halobenzoquinones at ng/L levels in drinking water. (United States)

    Huang, Rongfu; Wang, Wei; Qian, Yichao; Boyd, Jessica M; Zhao, Yuli; Li, Xing-Fang


    We report here the characterization of twelve halobenzoquinones (HBQs) using electrospray ionization (ESI) high resolution quadrupole time-of-flight mass spectrometry. The high resolution negative ESI spectra of the twelve HBQs formed two parent ions, [M + H(+) + 2e(-)], and the radical M(-•). The intensities of these two parent ions are dependent on their chemical structures and on instrumental parameters such as the source temperature and flow rate. The characteristic ions of the HBQs were used to develop an ultra pressure liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method. At the UPLC flow rate (400 μL/min) and under the optimized ESI conditions, eleven HBQs showed the stable and abundant transitions [M + H(+) + 2e(-)] → X(-) (X(-) representing Cl(-), Br(-), or I(-)), while dibromo-dimethyl-benzoquinone (DBDMBQ) showed only the transition of M(-•) → Br(-). The UPLC efficiently separates all HBQs including some HBQ isomers, while the MS/MS offers exquisite limits of detection (LODs) at subng/mL levels for all HBQs except DBDMBQ. Combined with solid phase extraction (SPE), the method LOD is down to ng/L. The results from analysis of authentic samples demonstrated that the SPE-UPLC-MS/MS method is reliable, fast, and sensitive for the identification and quantification of the twelve HBQs in drinking water.

  14. Comments on SR 97 chapters 4 and 5 and supporting documents

    Energy Technology Data Exchange (ETDEWEB)

    Chin-Fu Tsang [E. O. Lawrence Berkeley National Laboratory, CA (United States). Earth Sciences Division


    A review was conducted on Chapters 4 and 5 of the SKB SR 97 - Post Closure Safety Main Report, with a background study of Chapters 1-3, as well as a study of the related sections of support documents SKB TR 95-22, SKB TR 99-20 and SKB TR 99-07. Main comments include: (1) Need for Iteration and Integration between Model Conceptualization and Model Investigations; (2) Need for Reviews by Two Types of Experts; (3) Need for Structured Expert Elicitation and Documentation; (4) Need for Careful Definition of Base Scenario; (5) Suggestion of the Use of Zeroth Order Scenario; (6) Confusion in the Definition of 'Variables'; (7) Need to Ensure Inclusion of Tertiary and Higher-Order Coupled Processes; (8) Need to Consider Model Abstraction and Associated Uncertainty; (9) Need for Care in Handling Analyses at Different Levels of Details. Additional comments are made more specifically on the THMC diagrams.

  15. New mourners, old mourners: online memorial culture as a chapter in the history of mourning (United States)

    Walter, Tony


    How does online mourning differ from offline mourning? Throughout history, demographic, social and technological changes have altered mourners' social relationships with both the living and the dead, and hence their experiences of grief. Online technologies comprise the latest chapter in this story; earlier chapters include family/community mourning (pre-industrial), private mourning (twentieth century) and public mourning (turn of the millennium). Pervasive social media in which users generate their own content have significantly shifted mourners' social interactions and the norms that govern them, partly in new directions (such as enfranchising previously stigmatised griefs; more potential for conflict between mourners and others) but partly returning to something more like the relationships of the pre-industrial village (such as everyday awareness of mortality, greater use of religious imagery, more potential for conflict among mourners). Online, mourners can experience both greater freedom to be themselves and increased social pressure to conform to group norms as to who should be mourned and how.

  16. The Twelve Promises of Alcoholics Anonymous: psychometric measure validation and mediational testing as a 12-step specific mechanism of behavior change. (United States)

    Kelly, John F; Greene, M Claire


    Empirical support for the recovery utility of 12-step mutual-help organizations (MHOs) has led to increased investigation of how such organizations confer benefit. The Twelve Promises of Alcoholics Anonymous (AA) feature prominently in 12-step philosophy and culture and are one of the few documented explications of the cognitive, affective, and behavioral benefits that members might accrue. This study investigated the psychometric properties of a measure of AA's Twelve Promises and examined whether it mediated the effect of 12-step participation on abstinence. Young adults (N=302, M age 20.4 [1.6], range 18-25; 27% female; 95% White) enrolled in an addiction treatment effectiveness study completed assessments at intake and 3-, 6-, and 12-months post treatment including a 26-item, Twelve Promises Scale (TPS). Factor analyses examined the TPS' psychometrics and lagged mediational analyses tested the TPS as a mechanism of behavior change. Robust principal axis factoring extraction with Varimax rotation revealed a 2-factor solution explaining 45-58% of the variance across three administrations ("Psychological Wellbeing"=26-39%; "Freedom from Craving=17-21%); internal consistency was high (alpha=.83-.93). Both factors were found to increase in relation to greater 12-step participation, but significant mediation was found only for the Freedom from Craving factor explaining 21-34% of the effect of 12-step participation in increasing abstinence. The TPS shows potential as a conceptually relevant, and psychometrically sound measure and may be useful in helping elucidate the extent to which the Twelve Promises emerge as an independent benefit of 12-step participation and/or explain SUD remission and recovery. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  17. Analytic device including nanostructures

    KAUST Repository

    Di Fabrizio, Enzo M.


    A device for detecting an analyte in a sample comprising: an array including a plurality of pixels, each pixel including a nanochain comprising: a first nanostructure, a second nanostructure, and a third nanostructure, wherein size of the first nanostructure is larger than that of the second nanostructure, and size of the second nanostructure is larger than that of the third nanostructure, and wherein the first nanostructure, the second nanostructure, and the third nanostructure are positioned on a substrate such that when the nanochain is excited by an energy, an optical field between the second nanostructure and the third nanostructure is stronger than an optical field between the first nanostructure and the second nanostructure, wherein the array is configured to receive a sample; and a detector arranged to collect spectral data from a plurality of pixels of the array.

  18. Investigations of body scales in twelve Heterocapsa species (Peridiniales, Dinophyceae), including a new species H. pseudotriquetra sp. nov

    DEFF Research Database (Denmark)

    Iwataki, M.; Hansen, Gert; Sawaguchi, T.;


    basal plate and a three-dimensional construction composed of vertically standing uprights or spines and horizontal bars. This basic scale structure is considered to be a generic characteristic. Finer scale details such as the shape and presence of a central hole in the basal plate, the numbers...... of uprights, bars and spines are considered to be species-specific. Two types of scales were found within clonal cultures of H. arctica and H. circularisquama and it is suggested that these represent ‘mature' and ‘immature' body scales. Intraspecific variation of the basal plate ‘reticulation' was also...... observed. This variation was particularly evident in prolonged cultures of H. horiguchii and H. rotundata. The body-scale structure of 11 described species can be distinguished. However, two species, namely H. triquetra and H. pseudotriquetra, have the same scale morphology and are distinguished...

  19. Chapter 11. Fuel Economy: The Case for Market Failure

    Energy Technology Data Exchange (ETDEWEB)

    Greene, David L [ORNL; German, John [Environmental and Energy Analysis; Delucchi, Mark A [University of California, Davis


    The efficiency of energy using durable goods, from automobiles to home air conditioners, is not only a key determinant of economy-wide energy use but also of greenhouse gas (GHG) emissions, climate change and energy insecurity. Energy analysts have long noted that consumers appear to have high implicit discount rates for future fuel savings when choosing among energy using durable goods (Howarth and Sanstad, 1995). In modeling consumers choices of appliances, the Energy Information Administration (EIA) has used discount rates of 30 percent for heating systems, 69 percent for choice of refrigerator and up to 111 percent for choice of water heater (U.S. DOE/EIA, 1996). Several explanations have been offered for this widespread phenomenon, including asymmetric information, bounded rationality and transaction costs. This chapter argues that uncertainty combined with loss aversion by consumers is sufficient to explain the failure to adopt cost effective energy efficiency improvements in the market for automotive fuel economy, although other market failures appear to be present as well. Understanding how markets for energy efficiency function is crucial to formulating effective energy policies (see Pizer, 2006). Fischer et al., (2004), for example, demonstrated that if consumers fully value the discounted present value of future fuel savings, fuel economy standards are largely redundant and produce small welfare losses. However, if consumers value only the first three years of fuel savings, then fuel economy standards can significantly increase consumer welfare. The nature of any market failure that might be present in the market for energy efficiency would also affect the relative efficacy of energy taxes versus regulatory standards (CBO, 2003). If markets function efficiently, energy taxes would generally be more efficient than regulatory standards in increasing energy efficiency and reducing energy use. If markets are decidedly inefficient, standards would likely be

  20. Chapter 1. Impacts of the oceans on climate change. (United States)

    Reid, Philip C; Fischer, Astrid C; Lewis-Brown, Emily; Meredith, Michael P; Sparrow, Mike; Andersson, Andreas J; Antia, Avan; Bates, Nicholas R; Bathmann, Ulrich; Beaugrand, Gregory; Brix, Holger; Dye, Stephen; Edwards, Martin; Furevik, Tore; Gangstø, Reidun; Hátún, Hjálmar; Hopcroft, Russell R; Kendall, Mike; Kasten, Sabine; Keeling, Ralph; Le Quéré, Corinne; Mackenzie, Fred T; Malin, Gill; Mauritzen, Cecilie; Olafsson, Jón; Paull, Charlie; Rignot, Eric; Shimada, Koji; Vogt, Meike; Wallace, Craig; Wang, Zhaomin; Washington, Richard


    further releases of the potent greenhouse gas methane from hydrates and permafrost. The Southern Ocean plays a critical role in driving, modifying and regulating global climate change via the carbon cycle and through its impact on adjacent Antarctica. The Antarctic Peninsula has shown some of the most rapid rises in atmospheric and oceanic temperature in the world, with an associated retreat of the majority of glaciers. Parts of the West Antarctic ice sheet are deflating rapidly, very likely due to a change in the flux of oceanic heat to the undersides of the floating ice shelves. The final section on modelling feedbacks from the ocean to climate change identifies limitations and priorities for model development and associated observations. Considering the importance of the oceans to climate change and our limited understanding of climate-related ocean processes, our ability to measure the changes that are taking place are conspicuously inadequate. The chapter highlights the need for a comprehensive, adequately funded and globally extensive ocean observing system to be implemented and sustained as a high priority. Unless feedbacks from the oceans to climate change are adequately included in climate change models, it is possible that the mitigation actions needed to stabilise CO2 and limit temperature rise over the next century will be underestimated.

  1. What is the role of South Africa's Chapter 9 Institutions?

    African Journals Online (AJOL)


    Commission), the Commission for Gender Equality (CGE), the Auditor-General ... Act to matters in which "the State of the public in general is being prejudiced by ..... fragile – and recently united – polity, the Chapter 9s cover key aspects of.

  2. 41 CFR Appendix D to Chapter 301 - Glossary of Acronyms (United States)


    ... TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES Ch. 301, App. D Appendix D to Chapter 301—Glossary of Acronyms ATM: Automated Teller Machine CAS: Commercial Aviation Service(s) CDW: Collision Damage Waiver CFR: Code of... Command SES: Senior Executive Service SIT: Storage in Transit SSN: Social Security Number TCS: Temporary...

  3. Ethical & Legal Issues in School Counseling. Chapter 6: Special Issues. (United States)

    Sampson, James P., Jr.; And Others

    This document contains chapter 6 (5 articles) of a collection of 35 articles primarily from American Association for Counseling and Development (AACD) publications on the most important legal and ethical topics about which all school counselors need to be informed. "Ethical Issues Involved With the Use of Computer-Assisted Counseling, Testing, and…

  4. Landscape ecology: Past, present, and future [Chapter 4 (United States)

    Samuel A. Cushman; Jeffrey S. Evans; Kevin McGarigal


    In the preceding chapters we discussed the central role that spatial and temporal variability play in ecological systems, the importance of addressing these explicitly within ecological analyses and the resulting need to carefully consider spatial and temporal scale and scaling. Landscape ecology is the science of linking patterns and processes across scale in both...

  5. Chapter 11. Quality evaluation of apple by computer vision (United States)

    Apple is one of the most consumed fruits in the world, and there is a critical need for enhanced computer vision technology for quality assessment of apples. This chapter gives a comprehensive review on recent advances in various computer vision techniques for detecting surface and internal defects ...

  6. Chapter 3. Planning and design for habitat monitoring (United States)

    Christina D. Vojta; Lyman L. McDonald; C. Kenneth Brewer; Kevin S. McKelvey; Mary M Rowland; Michael I. Goldstein


    This chapter provides guidance for designing a habitat monitoring program so that it will meet the monitoring objective, will be repeatable, and will adequately represent habitat within the spatial extent of interest. Although a number of excellent resources are available for planning and designing a monitoring program for wildlife populations (e.g., Busch and Trexler...

  7. Forest management and water in the United States [Chapter 13 (United States)

    Daniel G. Neary


    This chapter outlines a brief history of the United States native forests and forest plantations. It describes the past and current natural and plantation forest distribution (map, area, main species), as well as main products produced (timber, pulp, furniture, etc.). Integrated into this discussion is a characterization of the water resources of the United States and...

  8. Chapter 13. Exploring Use of the Reserved Core

    Energy Technology Data Exchange (ETDEWEB)

    Holmen, John [Univ. of Utah, Salt Lake City, UT (United States). SCI Inst. and School of Computing; Humphrey, Alan [Univ. of Utah, Salt Lake City, UT (United States). SCI Inst. and School of Computing; Berzins, Martin [Univ. of Utah, Salt Lake City, UT (United States). SCI Inst. and School of Computing


    In this chapter, we illustrate benefits of thinking in terms of thread management techniques when using a centralized scheduler model along with interoperability of MPI and PThread. This is facilitated through an exploration of thread placement strategies for an algorithm modeling radiative heat transfer with special attention to the 61st core. This algorithm plays a key role within the Uintah Computational Framework (UCF) and current efforts taking place at the University of Utah to model next-generation, large-scale clean coal boilers. In such simulations, this algorithm models the dominant form of heat transfer and consumes a large portion of compute time. Exemplified by a real-world example, this chapter presents our early efforts in porting a key portion of a scalability-centric codebase to the Intel Xeon Phi coprocessor. Specifically, this chapter presents results from our experiments profiling the native execution of a reverse Monte-Carlo ray tracing-based radiation model on a single coprocessor. These results demonstrate that our fastest run configurations utilized the 61st core and that performance was not profoundly impacted when explicitly oversubscribing the coprocessor operating system thread. Additionally, this chapter presents a portion of radiation model source code, a MIC-centric UCF cross-compilation example, and less conventional thread management technique for developers utilizing the PThreads threading model.

  9. The role of place-based social learning [Chapter 7 (United States)

    Daniel R. Williams


    Hummel's observations on the limits of science to inform practice provides a useful starting point for a book chapter devoted to examining post-normal environmental policy where the "facts are uncertain, values in dispute, stakes high, and decisions urgent" (Funtowicz and Ravetz 1993, 739, 744). Central to the argument here is that the integration of...

  10. Woody biomass from short rotation energy crops. Chapter 2 (United States)

    R.S., Jr. Zalesny Jr.; M.W. Cunningham; R.B. Hall; J. Mirck; D.L. Rockwood; J.A. Stanturf; T.A. Volk


    Short rotation woody crops (SRWCs) are ideal for woody biomass production and management systems because they are renewable energy feedstocks for biofuels, bioenergy, and bioproducts that can be strategically placed in the landscape to conserve soil and water, recycle nutrients, and sequester carbon. This chapter is a synthesis of the regional implications of producing...

  11. Endocrine and exocrine function of the bovine testis. Chapter 2 (United States)

    This chapter is devoted to the endocrine and exocrine function of the normal bovine male testes. The discussion begins with a historical review of the literature dating back to Aristotle’s (300 BC) initial description of the anatomy of the mammalian testes. The first microscopic examination of the t...



    FENDOĞLU, Doç.Dr.Hasan Tahsin


    CHAPTER FOUR LIBERTY AND TURKISH CONSTITUTIONS: Doç.Dr.Hasan Tahsin FENDOĞLU ABSTRACT: Turkish Constitution of 1982 is the first and only Turkish Constitution that has a main purpose on strengthening the political power not the liberty or democr...

  13. Element cycling in upland/peatland watersheds Chapter 8. (United States)

    Noel Urban; Elon S. Verry; Steven Eisenreich; David F. Grigal; Stephen D. Sebestyen


    Studies at the Marcell Experimental Forest (MEF) have measured the pools, cycling, and transport of a variety of elements in both the upland and peatland components of the landscape. Peatlands are important zones of element retention and biogeochemical reactions that greatly influence the chemistry of surface water. In this chapter, we summarize findings on nitrogen (N...

  14. "Preescolar Na Casa": Teaching Parents To Teach Children. Chapter 3. (United States)

    Fernandez, Ermitas

    This chapter describes a school readiness program that has been implemented in rural Galicia (Spain) since 1977. Data reveal that 70 percent of Galicia's population lives in rural areas, the economy remains primarily agricultural, Galicians earn less than the national average and have the largest number of public assistance recipients, and there…

  15. Body cooling, modelling & risk assessment - Immersion Hypothermia Chapter

    NARCIS (Netherlands)

    Tikuisis, P; Daanen, H.A.M.


    This chapter describes a model that can be used to predict hypothermia during cold water immersion. Drowning in cold water might precede the onset of hypothermia due to cold shock, injury or incapacitation. As pointed out in Chap. 129, there are three phases of increasing incapacitation leading to l

  16. Body cooling, modelling & risk assessment - Immersion Hypothermia Chapter

    NARCIS (Netherlands)

    Tikuisis, P; Daanen, H.A.M.


    This chapter describes a model that can be used to predict hypothermia during cold water immersion. Drowning in cold water might precede the onset of hypothermia due to cold shock, injury or incapacitation. As pointed out in Chap. 129, there are three phases of increasing incapacitation leading to

  17. Chapter Two: Foundations for the Study of Practice (United States)

    Young, Richard F.


    In this chapter, the historical roots of contemporary Practice Theory are unearthed in the work of semioticians, philosophers, and anthropologists. Saussure's semiotic theory is contrasted with that of Peirce, and the importance of Peirce's work for understanding the context of signs is stressed. The philosophy of language in the writings of…

  18. A supply chain approach to biochar systems [Chapter 2 (United States)

    Nathaniel M. Anderson; Richard D. Bergman; Deborah S. Page-Dumroese


    Biochar systems are designed to meet four related primary objectives: improve soils, manage waste, generate renewable energy, and mitigate climate change. Supply chain models provide a holistic framework for examining biochar systems with an emphasis on product life cycle and end use. Drawing on concepts in supply chain management and engineering, this chapter presents...

  19. Nutraceuticals: possible future ingredients and food safety aspects. Chapter 19

    NARCIS (Netherlands)

    Prakash, V.; Boekel, van M.A.J.S.


    This chapter defines nutraceuticals as bioactive compounds that are extracted from their original food matrix. The importance and role of basic nutrients in the growth, maintenance, and wellness of the body are well established. Food supplies energy, nutrients (fats, carbohydrates, proteins,

  20. Improving Chapter 1 Delivery. ERIC/CUE Digest Number 39. (United States)

    Ascher, Carol

    Researchers and educators have begun to question whether Chapter 1 pull-out programs are the most effective method of delivering extra help to the students who need it. Pull-out programs are still the predominating type, but may be declining in popularity as in-class programs gain favor. This document summarizes a variety of program designs which…

  1. 78 FR 21879 - Improving 9-1-1 Reliability; Reliability and Continuity of Communications Networks, Including... (United States)


    ... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Chapter I Improving 9-1-1 Reliability; Reliability and Continuity of Communications Networks, Including Broadband Technologies AGENCY: Federal Communications Commission. ACTION: Notice...

  2. Definition of a Twelve-Point Polygonal SAA Boundaryfor the GLAST Mission

    Energy Technology Data Exchange (ETDEWEB)

    Djomehri, Sabra I.; /UC, Santa Cruz /SLAC


    The Gamma-Ray Large Area Space Telescope (GLAST), set to launch in early 2008, detects gamma rays within a huge energy range of 100 MeV - 300 GeV. Background cosmic radiation interferes with such detection resulting in confusion over distinguishing cosmic from gamma rays encountered. This quandary is resolved by encasing GLAST's Large Area Telescope (LAT) with an Anti-Coincidence Detector (ACD), a device which identifies and vetoes charged particles. The ACD accomplishes this through plastic scintillator tiles; when cosmic rays strike, photons produced induce currents in Photomultiplier Tubes (PMTs) attached to these tiles. However, as GLAST orbits Earth at altitudes {approx}550km and latitudes between -26 degree and 26 degree, it will confront the South Atlantic Anomaly (SAA), a region of high particle flux caused by trapped radiation in the geomagnetic field. Since the SAA flux would degrade the sensitivity of the ACD's PMTs over time, a determined boundary enclosing this region need be attained, signaling when to lower the voltage on the PMTs as a protective measure. The operational constraints on such a boundary require a convex SAA polygon with twelve edges, whose area is minimal ensuring GLAST has maximum observation time. The AP8 and PSB97 models describing the behavior of trapped radiation were used in analyzing the SAA and defining a convex SAA boundary of twelve sides. The smallest possible boundary was found to cover 14.58% of GLAST's observation time. Further analysis of defining a boundary safety margin to account for inaccuracies in the models reveals if the total SAA hull area is increased by {approx}20%, the loss of total observational area is < 5%. These twelve coordinates defining the SAA flux region are ready for implementation by the GLAST satellite.

  3. The correlation between reading and mathematics ability at age twelve has a substantial genetic component. (United States)

    Davis, Oliver S P; Band, Gavin; Pirinen, Matti; Haworth, Claire M A; Meaburn, Emma L; Kovas, Yulia; Harlaar, Nicole; Docherty, Sophia J; Hanscombe, Ken B; Trzaskowski, Maciej; Curtis, Charles J C; Strange, Amy; Freeman, Colin; Bellenguez, Céline; Su, Zhan; Pearson, Richard; Vukcevic, Damjan; Langford, Cordelia; Deloukas, Panos; Hunt, Sarah; Gray, Emma; Dronov, Serge; Potter, Simon C; Tashakkori-Ghanbaria, Avazeh; Edkins, Sarah; Bumpstead, Suzannah J; Blackwell, Jenefer M; Bramon, Elvira; Brown, Matthew A; Casas, Juan P; Corvin, Aiden; Duncanson, Audrey; Jankowski, Janusz A Z; Markus, Hugh S; Mathew, Christopher G; Palmer, Colin N A; Rautanen, Anna; Sawcer, Stephen J; Trembath, Richard C; Viswanathan, Ananth C; Wood, Nicholas W; Barroso, Ines; Peltonen, Leena; Dale, Philip S; Petrill, Stephen A; Schalkwyk, Leonard S; Craig, Ian W; Lewis, Cathryn M; Price, Thomas S; Donnelly, Peter; Plomin, Robert; Spencer, Chris C A


    Dissecting how genetic and environmental influences impact on learning is helpful for maximizing numeracy and literacy. Here we show, using twin and genome-wide analysis, that there is a substantial genetic component to children's ability in reading and mathematics, and estimate that around one half of the observed correlation in these traits is due to shared genetic effects (so-called Generalist Genes). Thus, our results highlight the potential role of the learning environment in contributing to differences in a child's cognitive abilities at age twelve.

  4. Developing a learning culture: twelve tips for individuals, teams and organizations. (United States)

    Stinson, Lynn; Pearson, David; Lucas, Beverley


    A culture of learning in providing health services and education for health professionals is a constant challenge for individuals, team and organizations. The importance of such a culture was highlighted by the findings of the Bristol Royal Infirmary Inquiry (2001). This was discussed in the context of the literature on the Learning Organization (Senge, 1990) at the 2004 Association of Medical Education in Europe (AMEE) conference, and reviewed a year later at the 2005 AMEE conference. This paper outlines twelve tips for educational and health service organizations in facilitating a culture of learning for their members and also offers specific advice to individual students and professionals.

  5. Abstracts and program proceedings of the 1994 meeting of the International Society for Ecological Modelling North American Chapter

    Energy Technology Data Exchange (ETDEWEB)

    Kercher, J.R.


    This document contains information about the 1994 meeting of the International Society for Ecological Modelling North American Chapter. The topics discussed include: extinction risk assessment modelling, ecological risk analysis of uranium mining, impacts of pesticides, demography, habitats, atmospheric deposition, and climate change.

  6. 34 CFR 364.2 - What is the purpose of the programs authorized by chapter 1 of title VII? (United States)


    ... SILS and CIL programs authorized by chapter 1 of title VII of the Act is to promote a philosophy of independent living (IL), including a philosophy of consumer control, peer support, self-help, self... integration and full inclusion of individuals with significant disabilities into the mainstream of...

  7. Thinking about Reading about Thinking about Reading about Thinking. Advanced Skills in Chapter 1. [Workshop. Leader's Guide. (United States)

    Advanced Technology, Inc., Indianapolis, IN.

    Designed to assist technical assistance center staff members and other inservice providers, this workshop leader's guide contains step-by-step procedures for preparing, organizing, and presenting a one-hour workshop on advanced skills for teachers, administrators, and others associated with Chapter 1 programs. Sections of the guide include: (1) an…

  8. Work environment perceptions following relocation to open-plan offices: A twelve-month longitudinal study. (United States)

    Bergström, Jessica; Miller, Michael; Horneij, Eva


    A workplace's design can have various positive or negative effects on the employees and since the 1970s the advantages and disadvantages of open-plan offices have been discussed. The aim of this study was to investigate perceived health, work environment and self-estimated productivity one month before and at three, six and twelve months after relocation from individual offices to an open-plan office environment. Employees from three departments within the same company group and who worked with relatively similar tasks and who were planned to be relocated from private offices to open-plan offices were invited to participate. Questionnaires comprising items from The Salutogenic Health Indicator Scale, The Work Experience Measurement Scale, the questionnaire by Brennan et al. about perceived performance and one question from the Work Ability Index were sent to participants one month before relocation (baseline) to open-plan offices and then at three, six and twelve months after relocation. At baseline, 82 questionnaires were sent out. The response rate was 85%. At the follow-ups 77-79 questionnaires were sent out and the response-rate was 70%-81%. At follow-ups, perceived health, job satisfaction and performance had generally deteriorated. The results of the study indicate that employees' perception of health, work environment and performance decreased during a 12 month period following relocation from individual offices to open-plan offices.

  9. Approximate analytic method for high-apogee twelve-hour orbits of artificial Earth's satellites (United States)

    Vashkovyaka, M. A.; Zaslavskii, G. S.


    We propose an approach to the study of the evolution of high-apogee twelve-hour orbits of artificial Earth's satellites. We describe parameters of the motion model used for the artificial Earth's satellite such that the principal gravitational perturbations of the Moon and Sun, nonsphericity of the Earth, and perturbations from the light pressure force are approximately taken into account. To solve the system of averaged equations describing the evolution of the orbit parameters of an artificial satellite, we use both numeric and analytic methods. To select initial parameters of the twelve-hour orbit, we assume that the path of the satellite along the surface of the Earth is stable. Results obtained by the analytic method and by the numerical integration of the evolving system are compared. For intervals of several years, we obtain estimates of oscillation periods and amplitudes for orbital elements. To verify the results and estimate the precision of the method, we use the numerical integration of rigorous (not averaged) equations of motion of the artificial satellite: they take into account forces acting on the satellite substantially more completely and precisely. The described method can be applied not only to the investigation of orbit evolutions of artificial satellites of the Earth; it can be applied to the investigation of the orbit evolution for other planets of the Solar system provided that the corresponding research problem will arise in the future and the considered special class of resonance orbits of satellites will be used for that purpose.

  10. Global surface temperature change analysis based on MODIS data in recent twelve years (United States)

    Mao, K. B.; Ma, Y.; Tan, X. L.; Shen, X. Y.; Liu, G.; Li, Z. L.; Chen, J. M.; Xia, L.


    Global surface temperature change is one of the most important aspects in global climate change research. In this study, in order to overcome shortcomings of traditional observation methods in meteorology, a new method is proposed to calculate global mean surface temperature based on remote sensing data. We found that (1) the global mean surface temperature was close to 14.35 °C from 2001 to 2012, and the warmest and coldest surface temperatures of the global in the recent twelve years occurred in 2005 and 2008, respectively; (2) the warmest and coldest surface temperatures on the global land surface occurred in 2005 and 2001, respectively, and on the global ocean surface in 2010 and 2008, respectively; and (3) in recent twelve years, although most regions (especially the Southern Hemisphere) are warming, global warming is yet controversial because it is cooling in the central and eastern regions of Pacific Ocean, northern regions of the Atlantic Ocean, northern regions of China, Mongolia, southern regions of Russia, western regions of Canada and America, the eastern and northern regions of Australia, and the southern tip of Africa. The analysis of daily and seasonal temperature change indicates that the temperature change is mainly caused by the variation of orbit of celestial body. A big data model based on orbit position and gravitational-magmatic change of celestial body with the solar or the galactic system should be built and taken into account for climate and ecosystems change at a large spatial-temporal scale.

  11. The surgery of peripheral nerves (including tumors)

    DEFF Research Database (Denmark)

    Fugleholm, Kåre


    Surgical pathology of the peripheral nervous system includes traumatic injury, entrapment syndromes, and tumors. The recent significant advances in the understanding of the pathophysiology and cellular biology of peripheral nerve degeneration and regeneration has yet to be translated into improved...... surgical techniques and better outcome after peripheral nerve injury. Decision making in peripheral nerve surgery continues to be a complex challenge, where the mechanism of injury, repeated clinical evaluation, neuroradiological and neurophysiological examination, and detailed knowledge of the peripheral...... nervous system response to injury are prerequisite to obtain the best possible outcome. Surgery continues to be the primary treatment modality for peripheral nerve tumors and advances in adjuvant oncological treatment has improved outcome after malignant peripheral nerve tumors. The present chapter...

  12. Comparative assay of fluorescent antibody test results among twelve European National Reference Laboratories using various anti-rabies conjugates

    DEFF Research Database (Denmark)

    Robardet, E.; Andrieu, S.; Rasmussen, Thomas Bruun


    Twelve National Reference Laboratories (NRLs) for rabies have undertaken a comparative assay to assess the comparison of fluorescent antibody test (FAT) results using five coded commercial anti-rabies conjugates (Biorad, Bioveta, Fujirebio, Millipore, and SIFIN conjugates). Homogenized positive...

  13. Saltcedar and Russian olive interactions with wildlife: Chapter 4 (United States)

    Bateman, Heather L.; Paxton, Eben


    control with protecting critical wildlife habitat.In this chapter, we present a synthesis of published literature on the use of saltcedar and Russian olive by wildlife and discuss how wildlife respond or are likely to respond to control measures for saltcedar and Russian olive and subsequent restoration efforts. We discuss responses of several groups of wildlife, including arthropods, birds, mammals, herpetofauna, and fish.

  14. Jet Engine Noise Generation, Prediction and Control. Chapter 86 (United States)

    Huff, Dennis L.; Envia, Edmane


    Aircraft noise has been a problem near airports for many years. It is a quality of life issue that impacts millions of people around the world. Solving this problem has been the principal goal of noise reduction research that began when commercial jet travel became a reality. While progress has been made in reducing both airframe and engine noise, historically, most of the aircraft noise reduction efforts have concentrated on the engines. This was most evident during the 1950 s and 1960 s when turbojet engines were in wide use. This type of engine produces high velocity hot exhaust jets during takeoff generating a great deal of noise. While there are fewer commercial aircraft flying today with turbojet engines, supersonic aircraft including high performance military aircraft use engines with similar exhaust flow characteristics. The Pratt & Whitney F100-PW-229, pictured in Figure la, is an example of an engine that powers the F-15 and F-16 fighter jets. The turbofan engine was developed for subsonic transports, which in addition to better fuel efficiency also helped mitigate engine noise by reducing the jet exhaust velocity. These engines were introduced in the late 1960 s and power most of the commercial fleet today. Over the years, the bypass ratio (that is the ratio of the mass flow through the fan bypass duct to the mass flow through the engine core) has increased to values approaching 9 for modern turbofans such as the General Electric s GE-90 engine (Figure lb). The benefits to noise reduction for high bypass ratio (HPBR) engines are derived from lowering the core jet velocity and temperature, and lowering the tip speed and pressure ratio of the fan, both of which are the consequences of the increase in bypass ratio. The HBPR engines are typically very large in diameter and can produce over 100,000 pounds of thrust for the largest engines. A third type of engine flying today is the turbo-shaft which is mainly used to power turboprop aircraft and helicopters

  15. Chapter 10: Mining genome-wide genetic markers.

    Directory of Open Access Journals (Sweden)

    Xiang Zhang

    Full Text Available Genome-wide association study (GWAS aims to discover genetic factors underlying phenotypic traits. The large number of genetic factors poses both computational and statistical challenges. Various computational approaches have been developed for large scale GWAS. In this chapter, we will discuss several widely used computational approaches in GWAS. The following topics will be covered: (1 An introduction to the background of GWAS. (2 The existing computational approaches that are widely used in GWAS. This will cover single-locus, epistasis detection, and machine learning methods that have been recently developed in biology, statistic, and computer science communities. This part will be the main focus of this chapter. (3 The limitations of current approaches and future directions.

  16. Development of a Launch Vehicle Manufacturing Process. Chapter 4 (United States)

    Vickers, John; Munafo, Paul M. (Technical Monitor)


    One of the goals of this chapter is to provide sufficient information so that you can develop a manufacturing process for a potential launch vehicle. With the variety of manufacturing options available, you might ask how this can possibly be done in the span of a single chapter. Actually, it will be quite simple because a basic manufacturing process is nothing more than a set of logical steps that are iterated until they produce a desired product. Although these statements seem simple and logical, don't let this simplicity fool you. Manufacturing problems with launch vehicles and their subassemblies have been the primary cause of project failures because the vehicle concept delivered to the manufacturing floor could not be built as designed.

  17. Computer modelling for ecosystem service assessment: Chapter 4.4 (United States)

    Dunford, Robert; Harrison, Paula; Bagstad, Kenneth J.


    Computer models are simplified representations of the environment that allow biophysical, ecological, and/or socio-economic characteristics to be quantified and explored. Modelling approaches differ from mapping approaches (Chapter 5) as (i) they are not forcibly spatial (although many models do produce spatial outputs); (ii) they focus on understanding and quantifying the interactions between different components of social and/or environmental systems and (iii)

  18. Chapter 18 - Gliadins in foods and the electronic tongue


    Veloso, Ana C. A.; Luís G. Dias; Rodrigues, Lígia R.; Peres, António M.


    The commercialization of safe foods is a main concern and should be ensured throughout the entire food supply chain. So, fast, sensitive, and reliable analytical methods are needed to identify food-related specific hazards, ensuring consumers protection and avoiding health problems. This chapter is focused on the emerging (bio)sensors to detect the heat-stable allergen gliadin in gluten-free foods. A brief overview concerning gliadin and its relation to celiac disease is provided. Several wor...

  19. Chapter 1. Impacts of the oceans on climate change.


    Reid, PC; Fischer, AC; Lewis-Brown, E; Meredith, MP; Sparrow, M; Andersson, AJ; Antia, A.; Bates, NR; Bathmann, U.; Beaugrand, G.; Brix, H.; Dye, S.; Edwards, M.; Furevik, T.; R. Gangstø


    The oceans play a key role in climate regulation especially in part buffering (neutralising) the effects of increasing levels of greenhouse gases in the atmosphere and rising global temperatures. This chapter examines how the regulatory processes performed by the oceans alter as a response to climate change and assesses the extent to which positive feedbacks from the ocean may exacerbate climate change. There is clear evidence for rapid change in the oceans. As the main heat store for the wor...

  20. The Impact of Alcoholics Anonymous on other substance abuse related Twelve Step programs (United States)

    Laudet, Alexandre B.


    This chapter explores the influence of the AA model on self-help fellowships addressing problems of drug dependence. Fellowships that have adapted the 12-step recovery model to other substances of abuse are reviewed; next similarities and differences between AA and drug-recovery 12-step organizations are examined; finally, we present empirical findings on patterns of attendance and perceptions of AA and Narcotics Anonymous (NA) among polydrug dependent populations, many of whom are cross-addicted to alcohol. Future directions in 12-step research are noted in closing. PMID:19115764

  1. Changes in lipids over twelve months after initiating protease inhibitor therapy among persons treated for HIV/AIDS

    Directory of Open Access Journals (Sweden)

    Hogg Robert S


    Full Text Available Abstract Background Protease inhibitors are known to alter the lipid profiles in subjects treated for HIV/AIDS. However, the magnitude of this effect on plasma lipoproteins and lipids has not been adequately quantified. Objective To estimate the changes in plasma lipoproteins and triglycerides occurring within 12 months of initiating PI-based antiretroviral therapy among HIV/AIDS afflicted subjects. Methods We included all antiretroviral naïve HIV-infected persons treated at St-Paul's Hospital, British Columbia, Canada, who initiated therapy with protease inhibitor antiretroviral (ARV drugs between August 1996 and January 2002 and who had at least one plasma lipid measurement. Longitudinal associations between medication use and plasma lipids were estimated using mixed effects models that accounted for repeated measures on the same subjects and were adjusted for age, sex, time dependent CD4+ T-cell count, and time dependent cumulative use of non-nucleoside reverse transcriptase inhibitors and adherence. The cumulative number of prescriptions filled for PIs was considered time dependent. We estimated the changes in the 12 months following any initiation of a PI based regimen. Results A total of 679 eligible subjects were dispensed nucleoside analogues and PI at the initiation of therapy. Over a median 47 months of follow-up (interquartile range (IQR: 29–62, subjects had a median of 3 (IQR: 1–6 blood lipid measurements. Twelve months after treatment initiation of PI use, there was an estimated 20% (95% confidence interval: 17% – 24% increase in total cholesterol and 22% (12% – 33% increase in triglycerides. Conclusions Twelve months after treatment initiation with PIs, statistically significant increases in total cholesterol and triglycerides levels were observed in HIV-infected patients under conditions of standard treatment. Our results contribute to the growing body of evidence implicating PIs in the development of blood lipid

  2. Measuring performance in off-patent drug markets: a methodological framework and empirical evidence from twelve EU Member States. (United States)

    Kanavos, Panos


    This paper develops a methodological framework to help evaluate the performance of generic pharmaceutical policies post-patent expiry or after loss of exclusivity in non-tendering settings, comprising five indicators (generic availability, time delay to and speed of generic entry, number of generic competitors, price developments, and generic volume share evolution) and proposes a series of metrics to evaluate performance. The paper subsequently tests this framework across twelve EU Member States (MS) by using IMS data on 101 patent expired molecules over the 1998-2010 period. Results indicate that significant variation exists in generic market entry, price competition and generic penetration across the study countries. Size of a geographical market is not a predictor of generic market entry intensity or price decline. Regardless of geographic or product market size, many off patent molecules lack generic competitors two years after loss of exclusivity. The ranges in each of the five proposed indicators suggest, first, that there are numerous factors--including institutional ones--contributing to the success of generic entry, price decline and market penetration and, second, MS should seek a combination of supply and demand-side policies in order to maximise cost-savings from generics. Overall, there seems to be considerable potential for faster generic entry, uptake and greater generic competition, particularly for molecules at the lower end of the market.

  3. Chapter 29: Using an Existing Environment in the VO (IDL) (United States)

    Miller, C. J.

    The local environment of a Brightest Cluster Galaxy (BCG) can provide insight into the (still not understood) formation process of the BCG itself. BCGs are the most massive galaxies in the Universe, and their formation and evolution are a popular and current research topic (Linden et al. 2006, Bernardi et al. 2006, Lauer et al. 2006). They have been studied for some time (Sandage 1972, Ostriker & Tremaine 1975, White 1976, Thuan & Romanishin 1981, Merritt 1985, Postman and Lauer 1995, among many others). Our goal in this chapter is to study how the local environment can affect the physical and measurable properties of BCGs. We will conduct an exploratory research exercise. In this chapter, we will show how the Virtual Observatory (VO) can be effectively utilized for doing modern scientific research on BCGs. We identify the scientific functionalities we need, the datasets we require, and the service locations in order to discover and access those data. This chapter utilizes IDL's VOlib, which is described in Chapter 24 of this book and is available at IDL provides the capability to perform the entire range of astronomical scientific analyses in one environment: from image reduction and analysis to complex catalog manipulations, statistics, and publication quality figures. At the 2005 and 2006 NVO Summer Schools, user statistics show that IDL was the most commonly used programming language by the students (nearly 3-to-1 over languages like IRAF, Perl, and Python). In this chapter we show how the integration of IDL to the VO through VOlib provides even greater capabilities and possibilities for conducting science in the era of the Virtual Observatory. The reader should familiarize themselves with the VOlib libraries before attempting the examples in this tutorial. We first build a research plan. We then discover the service URLs we will need to access the data. We then apply the necessary functions and tools to these data before we can do our

  4. Fundamentals of Physics, Volume 1, (Chapters 1 - 21) (United States)

    Walker, Jearl


    Chapter 1. Measurement 1. How does the appearance of a new type of cloud signal changes in Earth's atmosphere? 1-1 What Is Physics? 1-2 Measuring Things. 1-3 The International System of Units. 1-4 Changing Units. 1-5 Length. 1-6 Time. 1-7 Mass. Review & Summary. Problems. Chapter 2. Motion Along a Straight Line. What causes whiplash injury in rear-end collisions of cars? 2-1 What Is Physics? 2-2 Motion. 2-3 Position and Displacement. 2-4 Average Velocity and Average Speed. 2-5 Instantaneous Velocity and Speed. 2-6 Acceleration. 2-7 Constant Acceleration: A Special Case. 2-8 Another Look at Constant Acceleration. 2-9 Free-Fall Acceleration. 2-10 Graphical Integration in Motion Analysis. 2 Review & Summary. Questions. Problems. Chapter 3. Vectors. How does an ant know the way home with no guiding clues on the desert plains? 3-1 What Is Physics? 3-2 Vectors and Scalars. 3-3 Adding Vectors Geometrically. 3-4 Components of Vectors. 3-5 Unit Vectors. 3-6 Adding Vectors by Components. 3-7 Vectors and the Laws of Physics. 3-8 Multiplying Vectors. Review & Summary. Questions. Problems. Chapter 4. Motion in Two and Three Dimensions. In a motorcycle jump for record distance, where does the jumper put the second ramp? 4-1 What Is Physics? 4-2 Position and Displacement. 4-3 Average Velocity and Instantaneous Velocity. 4-4 Average Acceleration and Instantaneous Acceleration. 4-5 Projectile Motion. 4-6 Projectile Motion Analyzed. 4-7 Uniform Circular Motion. 4-8 Relative Motion in One Dimension. 4-9 Relative Motion in Two Dimensions. Review & Summary. Questions. Problems. Chapter 5. Force and Motion--I. When a pilot takes off from an aircraft carrier, what causes the compulsion to .y the plane into the ocean? 5-1 What Is Physics? 5-2 Newtonian Mechanics. 5-3 Newton's First Law. 5-4 Force. 5-5 Mass. 5-6 Newton's Second Law. 5-7 Some Particular Forces. 5-8 Newton's Third Law. 5-9 Applying Newton's Laws. Review & Summary. Questions. Problems. Chapter 6. Force and Motion--II. Can a

  5. Exploring Content Schemata Influence on L2 Reading: The Hunted Fox and Twelve and Not Stupid

    Directory of Open Access Journals (Sweden)

    Amizura Hanadi Mohd Radzi


    Full Text Available This paper will discuss the aspects of content schemata in second language reading among diploma level students who were taking a reading course in Universiti Teknologi MARA Perlis. In this qualitative case study, the researcher had selected two short stories that are categorized as content-familiar texts, i.e. The Hunted Fox and Twelve and Not Stupid. Six participants were asked to write a 150-word entry response on the short story and a grading criteria was used to assess the participants’ level of comprehension. An in-depth interview was also conducted on each participant. The entry responses and the interview patterns were analyzed to determine whether content schemata had contributed to the learners’ understanding of the text. This study discovered that content schemata had contributed to the learners’ understanding of the text because the learners’ comprehension was facilitated by their background knowledge on the content-familiar texts.

  6. Proteomic characterization of human milk whey proteins during a twelve-month lactation period. (United States)

    Liao, Yalin; Alvarado, Rudy; Phinney, Brett; Lönnerdal, Bo


    Human milk is a rich source of bioactive proteins that support the early growth and development of the newborn. Although the major components of the protein fraction in human milk have been studied, the expression and relative abundance of minor components have received limited attention. We examined the expression of low-abundance proteins in the whey fraction of human milk and their dynamic changes over a twelve-month lactation period. The low-abundance proteins were enriched by ProteoMiner beads, and protein identification was performed by liquid chromatography tandem mass spectrometry. One hundred and fifteen proteins were identified, thirty-eight of which have not been previously reported in human colostrum or milk. We also for the first time described differences in protein patterns among the low-abundance proteins during lactation. These results enhance our knowledge about the complexity of the human milk proteome, which constitutes part of the advantages to the breast-fed infant.

  7. Fate of the conformal fixed point with twelve massless fermions and SU(3) gauge group

    CERN Document Server

    Fodor, Zoltan; Kuti, Julius; Mondal, Santanu; Nogradi, Daniel; Wong, Chik Him


    We report new results on the conformal properties of an important strongly coupled gauge theory, a building block of composite Higgs models beyond the Standard Model. With twelve massless fermions in the fundamental representation of the SU(3) color gauge group, an infrared fixed point of the $\\beta$-function was recently reported in the theory (Cheng:2014jba) with uncertainty in the location of the critical gauge coupling inside the narrow $[ 6.0

  8. Twelve Tips for teaching medical professionalism at all levels of medical education. (United States)

    Al-Eraky, Mohamed Mostafa


    Review of studies published in medical education journals over the last decade reveals that teaching medical professionalism is essential, yet challenging. According to a recent Best Evidence in Medical Education (BEME) guide, there is no consensus on a theoretical or practical model to integrate the teaching of professionalism into medical education. The aim of this article is to outline a practical manual for teaching professionalism at all levels of medical education. Drawing from research literature and author's experience, Twelve Tips are listed and organised in four clusters with relevance to (1) the context, (2) the teachers, (3) the curriculum, and (4) the networking. With a better understanding of the guiding educational principles for teaching medical professionalism, medical educators will be able to teach one of the most challenging constructs in medical education.

  9. Comparative analysis and supragenome modeling of twelve Moraxella catarrhalis clinical isolates

    Directory of Open Access Journals (Sweden)

    Hermans Peter WM


    Full Text Available Abstract Background M. catarrhalis is a gram-negative, gamma-proteobacterium and an opportunistic human pathogen associated with otitis media (OM and exacerbations of chronic obstructive pulmonary disease (COPD. With direct and indirect costs for treating these conditions annually exceeding $33 billion in the United States alone, and nearly ubiquitous resistance to beta-lactam antibiotics among M. catarrhalis clinical isolates, a greater understanding of this pathogen's genome and its variability among isolates is needed. Results The genomic sequences of ten geographically and phenotypically diverse clinical isolates of M. catarrhalis were determined and analyzed together with two publicly available genomes. These twelve genomes were subjected to detailed comparative and predictive analyses aimed at characterizing the supragenome and understanding the metabolic and pathogenic potential of this species. A total of 2383 gene clusters were identified, of which 1755 are core with the remaining 628 clusters unevenly distributed among the twelve isolates. These findings are consistent with the distributed genome hypothesis (DGH, which posits that the species genome possesses a far greater number of genes than any single isolate. Multiple and pair-wise whole genome alignments highlight limited chromosomal re-arrangement. Conclusions M. catarrhalis gene content and chromosomal organization data, although supportive of the DGH, show modest overall genic diversity. These findings are in stark contrast with the reported heterogeneity of the species as a whole, as wells as to other bacterial pathogens mediating OM and COPD, providing important insight into M. catarrhalis pathogenesis that will aid in the development of novel therapeutic regimens.

  10. BaBar technical design report: Chapter 9, Magnet coil and flux return

    Energy Technology Data Exchange (ETDEWEB)

    O`Connor, T.; The BaBar Collaboration


    The BaBar magnet is a thin, 1.5 T superconducting solenoid with a hexagonal flux return. This chapter discusses the physics requirements and performance goals for the magnet, describes key interfaces, and summarizes the projected magnet performance. It also presents the design of the superconducting solenoid, including magnetic design, cold mass design, quench protection and stability, cold mass cooling, cryostat design, and coil assembly and transportation. The cryogenic supply system and instrumentation are described briefly, and the flux return is described.

  11. [Different headache forms of chapter 4 of the International Headache Classification]. (United States)

    Göbel, A; Heinze, A; Göbel, H


    Chapter 4 of the International Classification of Headaches contains a group of clinically very heterogeneous primary headache forms. Little is known about the pathogenesis of these headache types and therapy is usually based on isolated case reports and uncontrolled studies. The forms include primary stabbing headache, primary cough headache, primary exertional headache, primary headache associated with sexual activity, hypnic headache, primary thunderclap headache, hemicrania continua and the new daily persistent headache. Some of these headache forms may be of a symptomatic nature and require careful examination, imaging and further tests. Primary and secondary headache forms must be carefully distinguished.

  12. Site characterization plan: Yucca Mountain Site, Nevada Research and Development Area, Nevada: Volume 4, Part B: Chapter 8, Sections 8.0 through

    Energy Technology Data Exchange (ETDEWEB)



    This site characterization plan (SCP) has been developed for the candidate repository site at Yucca Mountain in the State of Nevada. The SCP includes a description of the Yucca Mountain site (Chapters 1-5), a conceptual design for the repository (Chapter 6), a description of the packaging to be used for the waste to be emplaced in the repository (Chapter 7), and a description of the planned site characterization activities (Chapter 8). The schedules and milestones presented in Sections 8.3 and 8.5 of the SCP were developed to be consistent with the June 1988 draft Amendment to the DOE`s Mission Plan for the Civilian Radioactive Waste Management Program. The five month delay in the scheduled start of exploratory shaft construction that was announced recently is not reflected in these schedules. 74 figs., 32 tabs.

  13. Site characterization plan: Yucca Mountain Site, Nevada Research and Development Area, Nevada: Volume 2, Part A: Chapters 3, 4, and 5

    Energy Technology Data Exchange (ETDEWEB)



    This site characterization plan (SCP) has been developed for the candidate repository site at Yucca Mountain in the State of Nevada. The SCP includes a description of the Yucca Mountain site (Chapters 1--5), a conceptual design for the repository (Chapter 6), a description of the packaging to be used for the waste to be emplaced in the repository (Chapter 7), and a description of the planned site characterization activities (Chapter 8). The schedules and milestones presented in Sections 8.3 and 8.5 of the SCP were developed to be consistent with the June 1988 draft Amendment to the DOE`s Mission Plan for the Civilian Radioactive Waste Management Program. The five month delay in the scheduled start of exploratory shaft construction that was announced recently is not reflected in these schedules. 575 refs., 84 figs., 68 tabs.

  14. Chapter Leadership Profiles among Citizen Activists in the Drunk Driving Movement. (United States)

    Ungerleider, Steven; Bloch, Steven


    Study of Mothers Against Drunk Drivers (MADD) analyzed the chapter emphasis, levels of satisfaction and relationship to national office on several measures. Surveying 212 chapters, MADD leadership provided profile of independent, autonomous activists in the drunk driving countermeasure movement. (Author)

  15. Chapter 6: The scientific basis for conserving forest carnivores: considerations for management (United States)

    L. Jack Lyon; Keith B. Aubry; William J. Zielinski; Steven W. Buskirk; Leonard F. Ruggiero


    The reviews presented in previous chapters reveal substantial gaps in our knowledge about marten, fisher, lynx, and wolverine. These gaps severely constrain our ability to design reliable conservation strategies. This problem will be explored in depth in Chapter 7. In this chapter, our objective is to discuss management considerations resulting from what we currently...

  16. A Summary of State Chapter 1 Participation and Achievement Information -- 1990-91. (United States)

    Sinclair, Beth; Gutmann, Babette

    This report summarizes the 1990-91 State Performance Reports for the Chapter 1 (Education Consolidation and Improvement Act) local education agency (LEA) program and the Chapter 1 State Agency Neglected or Delinquent program. Chapter 1 represents the largest investment in elementary and secondary education of the Federal government. With the…

  17. State Chapter 1 Participation and Achievement Information--1992-93. Summary Report. (United States)

    Sinclair, Beth; Gutmann, Babette

    This report summarizes the 1992-93 State Performance Reports for the Chapter 1 Local Education Agency (LEA) program and the Chapter 1 State Agency Neglected or Delinquent Program. The Neglected or Delinquent Program serves youth in state-operated correctional facilities and in facilities for neglected youth. Chapter 1 participation has steadily…

  18. Advanced-Skill Instruction in Chapter 1 Summer Programs and Student Achievement. (United States)

    D'Agostino, Jerome; Hiestand, Nancy

    Summer school is thought to be an effective alternative delivery mode for Chapter 1 education. The effectiveness of summer Chapter 1 programs was studied during Fall 1993 in 68 Chicago (Illinois) public schools. Students who had been in fourth grade in 1991-92 were divided into a group that had received Chapter 1 help during the school year and…

  19. Chapter 18: Web-based Tools - NED VO Services (United States)

    Mazzarella, J. M.; NED Team

    The NASA/IPAC Extragalactic Database (NED) is a thematic, web-based research facility in widespread use by scientists, educators, space missions, and observatory operations for observation planning, data analysis, discovery, and publication of research about objects beyond our Milky Way galaxy. NED is a portal into a systematic fusion of data from hundreds of sky surveys and tens of thousands of research publications. The contents and services span the entire electromagnetic spectrum from gamma rays through radio frequencies, and are continuously updated to reflect the current literature and releases of large-scale sky survey catalogs. NED has been on the Internet since 1990, growing in content, automation and services with the evolution of information technology. NED is the world's largest database of crossidentified extragalactic objects. As of December 2006, the system contains approximately 10 million objects and 15 million multi-wavelength cross-IDs. Over 4 thousand catalogs and published lists covering the entire electromagnetic spectrum have had their objects cross-identified or associated, with fundamental data parameters federated for convenient queries and retrieval. This chapter describes the interoperability of NED services with other components of the Virtual Observatory (VO). Section 1 is a brief overview of the primary NED web services. Section 2 provides a tutorial for using NED services currently available through the NVO Registry. The "name resolver" provides VO portals and related internet services with celestial coordinates for objects specified by catalog identifier (name); any alias can be queried because this service is based on the source cross-IDs established by NED. All major services have been updated to provide output in VOTable (XML) format that can be accessed directly from the NED web interface or using the NVO registry. These include access to images via SIAP, Cone- Search queries, and services providing fundamental, multi

  20. Skull lichens: a curious chapter in the history of phytotherapy. (United States)

    Modenesi, P


    Lichens growing on skulls were known in late medieval times as usnea or moss of a dead man's skull and were recommended as highly beneficial in various diseases. They were, in addition, the main ingredient of Unguentum armariun, a liniment used in a curious medical practice: the magnetic cure of wounds. We can place this chapter of the history of phytotherapy within the wider cultural context of the period, which saw the definition of nature become increasingly more fluid and open to a variety of novel interpretations.

  1. Fundamentals of Physics, Part 2 (Chapters 12-20) (United States)

    Halliday, David; Resnick, Robert; Walker, Jearl


    Chapter 12 Equilibrium and Elasticity. What injury can occur to a rock climber hanging by a crimp hold? 12-1 What Is Physics? 12-2 Equilibrium. 12-3 The Requirements of Equilibrium. 12-4 The Center of Gravity. 12-5 Some Examples of Static Equilibrium. 12-6 Indeterminate Structures. 12-7 Elasticity. Review & Summary Questions Problems. Chapter 13 Gravitation. What lies at the center of our Milky Way galaxy? 13-1 What Is Physics? 13-2 Newton's Law of Gravitation. 13-3 Gravitation and the Principle of Superposition. 13-4 Gravitation Near Earth's Surface. 13-5 Gravitation Inside Earth. 13-6 Gravitational Potential Energy. 13-7 Planets and Satellites: Kepler's Laws. 13-8 Satellites: Orbits and Energy. 13-9 Einstein and Gravitation. Review & Summary Questions Problems. Chapter 14 Fluids. What causes ground effect in race car driving? 14-1 What Is Physics? 14-2 What Is a Fluid? 14-3 Density and Pressure. 14-4 Fluids at Rest. 14-5 Measuring Pressure. 14-6 Pascal's Principle. 14-7 Archimedes' Principle. 14-8 Ideal Fluids in Motion. 14-9 The Equation of Continuity. 14-10 Bernoulli's Equation. Review & SummaryQuestionsProblems. Chapter 15 Oscillations. What is the "secret" of a skilled diver's high catapult in springboard diving? 15-1 What Is Physics? 15-2 Simple Harmonic Motion. 15-3 The Force Law for Simple Harmonic Motion. 15-4 Energy in Simple Harmonic Motion. 15-5 An Angular Simple Harmonic Oscillator. 15-6 Pendulums. 15-7 Simple Harmonic Motion and Uniform Circular Motion. 15-8 Damped Simple Harmonic Motion. 15-9 Forced Oscillations and Resonance. Review & Summary Questions Problems. Chapter 16 Waves--I. How can a submarine wreck be located by distant seismic stations? 16-1 What Is Physics? 16-2 Types of Waves. 16-3 Transverse and Longitudinal Waves. 16-4 Wavelength and Frequency. 16-5 The Speed of a Traveling Wave. 16-6 Wave Speed on a Stretched String. 16-7 Energy and Power of a Wave Traveling Along a String. 16-8 The Wave Equation. 16-9 The Principle of Superposition

  2. Selenium poisoning of fish and wildlife in nature: lessons from twelve real-world examples

    Energy Technology Data Exchange (ETDEWEB)

    Skorupa, J.P. [United States Fish and Wildlife Service, Sacramento, CA (United States)


    The chapter presents an inventory of real-world case studies of clearly confirmed or highly probable selenium poisoning in nature. These are of: Belews Lake, North Carolina, Hyco Reservoir in North Carolina, and Martin Reservoir, Texas, all constructed to provide cooling water for large coal-fired power plants; constructed wetland at the Chevron Richmond oil refinery California; Salton Sea, Kesterson Reservoir and Tulane Basin in California, constructed for agricultural drainage; seepage wetlands constructed for the Kenrick Reclamation Project near Casper, Wyoming and at the Ouray National Wildlife Refuse in Utah; an agroforestry demonstration site at Red Rock Ranch, California; Swietzer Lake, Colorado, constructed for recreational purposes and Lake Oltertjarn in Sweden, treated with selenite to mitigate mercury levels in fish. Lessons learned from these studies and the applicability of the US GPA`s freshwater chronic criterion for selenium of 5 {mu}g/L are discussed. 116 refs., 5 figs., 1 tab.

  3. Twelve-year cyclic surging episode at Donjek Glacier in Yukon, Canada (United States)

    Furuya, M.; Abe, T.; Sakakibara, D.


    Surge-type glaciers exhibit several-fold to orders-of-magnitude speed-up during the short active phase, resulting in km-scale terminus advance. Although there are many surge-type glaciers near the border of Alaska and the Yukon, the generation mechanisms remain uncertain because of limited and few continuous observations. To better understand the surge dynamics and predict the next event, it is essential to examine the entire surge cycles. Here we use Landsat optical imageries to reveal the long-term evolutions, and report three surging episodes at Donjek Glacier in Yukon, Canada. Using the Landsat images, we found three surging events in 1989, 2001, and 2013. In the 2001 event, the surface speed significantly increased by up to 4.5 m/d; during the quiescent phases it was ~0.5 m/d at the terminus. While the duration of active phase is about 4~5 and 2~3 year in the 2001 and 2013 events, the period in the 1989 event is unclear because of the lack of high temporal resolution data. Remarkably, the surging area is limited to the ~20-km section from the terminus instead of the entire glacier. Moreover, we examined the terminus area changes from 1975 to 2014. Although the area has been secularly decreasing probably due to the tread of global warming, it has also revealed four significant fluctuations during the nearly forty years. Comparing the speed and the area changes, the three speed-up events correspond to the terminus area fluctuations with a few time lags. It turns out that the surge event has been quite regularly repeating every twelve years. Although the behavior is rather similar to that in Svalbard glaciers in terms of maximum speed and unclear initiation season, the recurrence interval is much shorter than other nearby surges. Considering that the surge events seem to have initiated around significantly narrower area than upstream, the strong valley constriction may control the regularity as well as the twelve-year recurrence time.


    Ribas-Filho, Jurandir Marcondes; Malafaia, Osvaldo; Czeczko, Nicolau Gregori; Ribas, Carmen A P Marcondes; Nassif, Paulo Afonso Nunes


    To propose metrics to qualify the publication in books and chapters, and from there, establish guidance for the evaluation of the Medicine III programs. Analysis of some of the 2013 area documents focusing this issue. Were analyzed the following areas: Computer Science; Biotechnology; Biological Sciences I; Public Health; Medicine I. Except for the Medicine I, which has not adopted the metric for books and chapters, all other programs established metrics within the intellectual production, although with unequal percentages. It´s desirable to include metrics for books and book chapters in the intellectual production of post-graduate programs in Area Document with percentage-value of 5% in publications of Medicine III programs. Propor a métrica para qualificar a produção veiculada através de livros e capítulos e, a partir daí, estabelecer orientação para a avaliação dos programas de pós-graduação da Medicina III. Análise dos documentos de área de 2013 dos programas de pós-graduação senso estrito das áreas: Ciência da Computação; Biotecnologia; Ciências Biológicas I; Saúde Coletiva; Medicina I. Excetuando-se o programa da Medicina I, que não adotou a métrica para classificação de livros e capítulos, todos os demais estabeleceram-na dentro da sua produção intelectual, embora com percentuais desiguais. É desejável inserir a métrica de livros e capitulos de livros na produção intelectual do Documento de Área dos programas, ortorgando a ela percentual de 5% das publicações qualificadas dos programas da Medicina III.

  5. Evolution and potential function of fibrinogen-like domains across twelve Drosophila species

    Directory of Open Access Journals (Sweden)

    Middha Sumit


    Full Text Available Abstract Background The fibrinogen-like (FBG domain consists of approximately 200 amino acid residues, which has high sequence similarity to the C-terminal halves of fibrinogen β and γ chains. Fibrinogen-related proteins (FREPs containing one or more FBG domains are found universally in vertebrates and invertebrates. In invertebrates, FREPs are involved in immune responses and other aspects of physiology. To understand the complexity of this gene family in Drosophila, we analyzed FREPs in twelve Drosophila species. Results Using the genome data from 12 Drosophila species, we identified FBG domains in each species. The results show that the gene numbers in each species vary from 14 genes up to 43 genes. Using sequence profile analysis, we found that FBG domains have high sequence similarity and are highly conserved throughout. By comparison of structure and sequence conservation, some of the FBG domains in Drosophila melanogaster are predicted to function in recognition of carbohydrates and their derivatives on the surface of microorganisms in innate immunity. Conclusion Sequence and structural analyses show that FREP family across 12 Drosophila species contains conserved FBG domains. Expansion of the FREP families in Drosophila is mainly accounted by a major expansion of FBG domains.

  6. Twelve-Year Trends of PM10 and Visibility in the Hefei Metropolitan Area of China

    Directory of Open Access Journals (Sweden)

    Lin Huang


    Full Text Available China has been experiencing severe air pollution and previous studies have mostly focused on megacities and a few hot spot regions. Hefei, the provincial capital city of Anhui province, has a population of near 5 million in its metropolitan area, but its air quality has not been reported in literature. In this study, daily PM10 and visibility data in 2001–2012 were analyzed to investigate the air quality status as well as the twelve-year pollution trends in Hefei. The results reveal that Hefei has been suffering high PM10 pollution and low visibility during the study period. The annual average PM10 concentrations are 2~3 times of the Chinese Ambient Air Quality Standard. PM10 shows fluctuating variation in 2001–2007 and has a slightly decreasing trend after 2008. The annual average visibility range is generally lower than 7 km and shows a worsening trend from 2001 to 2006 followed by an improving trend from 2007 to 2012. Wind speed, precipitation, and relative humidity have negative effects on PM10 concentrations in Hefei, while temperature could positively or negatively affect PM10. The results provide a general understanding of the status and long-term trends of PM10 pollution and visibility in a typical second-tier city in China.

  7. Validation of Twelve Small Kepler Transiting Planets in the Habitable Zone

    CERN Document Server

    Torres, Guillermo; Fressin, Francois; Caldwell, Douglas A; Twicken, Joseph D; Ballard, Sarah; Batalha, Natalie M; Bryson, Stephen T; Ciardi, David R; Henze, Christopher E; Howell, Steve B; Isaacson, Howard T; Jenkins, Jon M; Muirhead, Philip S; Newton, Elisabeth R; Petigura, Erik A; Barclay, Thomas; Borucki, William J; Crepp, Justin R; Everett, Mark E; Horch, Elliott P; Howard, Andrew W; Kolbl, Rea; Marcy, Geoffrey W; McCauliff, Sean; Quintana, Elisa V


    We present an investigation of twelve candidate transiting planets from Kepler with orbital periods ranging from 34 to 207 days, selected from initial indications that they are small and potentially in the habitable zone (HZ) of their parent stars. The expected Doppler signals are too small to confirm them by demonstrating that their masses are in the planetary regime. Here we verify their planetary nature by validating them statistically using the BLENDER technique, which simulates large numbers of false positives and compares the resulting light curves with the Kepler photometry. This analysis was supplemented with new follow-up observations (high-resolution optical and near-infrared spectroscopy, adaptive optics imaging, and speckle interferometry), as well as an analysis of the flux centroids. For eleven of them (KOI-0571.05, 1422.04, 1422.05, 2529.02, 3255.01, 3284.01, 4005.01, 4087.01, 4622.01, 4742.01, and 4745.01) we show that the likelihood they are true planets is far greater than that of a false po...

  8. Measurement and analysis of angular velocity variations of twelve-cylinder diesel engine crankshaft (United States)

    Bulatović, Ž. M.; Štavljanin, M. S.; Tomić, M. V.; Knežević, D. M.; Biočanin, S. Lj.


    This paper presents the procedures for measuring and analyzing the angular velocity variation of twelve-cylinder diesel engine crankshaft on its free end and on the power-output end. In addition, the paper deals with important aspects of the measurement of crankshaft torsional oscillations. The method is based on digital encoders placed at two distances, and one of them is a sensor not inserted directly on the shaft, i.e. a non-contact method with a toothed disc is used. The principle based on toothed disc is also used to measure the actual camshaft angular velocity of in-line compact high-pressure pump the engine is equipped with, and this paper aims to demonstrate the possibility of measuring the actual angular velocity of any rotating shaft in the engine, on which it is physically possible to mount a toothed disc. The method was created completely independently during long-range development and research tests of V46 family engines. This method is specific for its particular adaptability for use on larger engines with extensive vibrations and torsional oscillations. The main purpose of this paper is a practical contribution to all the more interesting research of the use of engine crankshaft angular velocity as a diagnostic tool for identifying the engine irregular running.

  9. Access to oral health services in children under twelve years of age in Peru, 2014

    Directory of Open Access Journals (Sweden)

    Akram Hernández-Vásquez


    Full Text Available The aim of the study was to explore the patterns of dental health services access in children under twelve years of age in Peru. Data from 25,285 children under 12 years who participated in the Demographic and Family Health Survey of 2014 were reviewed. An exploratory spatial analysis was performed to project the proportions of children with access to dental health services, according to national regions, type of health service and urban or rural place of residence. The results show that of the total sample, 26.7% had access to dental health services in the last six months, 39.6% belonged to the age group 0-4 years, 40.6% lived in the Andean region and 58.3% lived in urban areas. The regions of Huancavelica, Apurimac, Ayacucho, Lima and Pasco had the highest percentages of access nationwide. In conclusion, there is low access to dental health services in the population under 12 years of age in Peru. The spatial distribution of access to dental health services allows regions to be identified and grouped according to similar access patterns, in order to better focus public health actions.

  10. Synergy between Seeking Safety and Twelve-Step Affiliation on Substance Use Outcomes for Women (United States)

    Morgan-Lopez, Antonio A.; Saavedra, Lissette M.; Hien, Denise A.; Campbell, Aimee N.; Wu, Elwin; Ruglass, Lesia


    Objective The Recovery Management paradigm provides a conceptual framework for the examination of joint impact of a focal treatment and post-treatment service utilization on substance abuse treatment outcomes. We test this framework by examining the interactive effects of a treatment for comorbid PTSD and substance use, Seeking Safety, and post-treatment Twelve-Step Affiliation (TSA) on alcohol and cocaine use. Method Data from 353 women in a six-site, randomized controlled effectiveness trial within the NIDA Clinical Trials Network were analyzed under latent class pattern mixture modeling. LCPMM was used to model variation in Seeking Safety by TSA interaction effects on alcohol and cocaine use. Results Significant reductions in alcohol use among women in Seeking Safety (compared to Health Education) were observed; women in the Seeking Safety condition who followed up with TSA had the greatest reductions over time in alcohol use. Reductions in cocaine use over time were also observed but did not differ between treatment conditions nor were there interactions with post-treatment TSA. Conclusions Findings advance understanding of the complexities for treatment and continuing recovery processes for women with PTSD and SUDs, and further support the chronic disease model of addiction. PMID:23558158

  11. Coréia aguda na gravidez Acute chorea in pregnancy: comments on twelve consecutive cases

    Directory of Open Access Journals (Sweden)

    Walter C. Pereira


    Full Text Available São apresentados doze casos de coréia aguda observados entre 150.000 gestantes (1/12.500. A maioria dos surtos ocorreu no segundo trimestre da primeira gravidez. A duração média dos sintomas foi de três meses, não tendo sido registrado caso algum de óbito materno. Todos os partos foram espontâneos e normais. Houve apenas um óbito fetal conseqüente a choque hemorrágico. São tecidas considerações a propósito dos aspectos clínico, laboratorial e prognóstico da coréia gravídica, sendo focalizado mais pormenorizadamente o problema fisiopatogênico dessa afecção.Twelve consecutive cases of acute chorea occurring among 150.000 pregnant women (1/12.500 are reported. Most of the cases occurred from the fourth do the sixth month of the first pregnancy. The average duration of the symptoms was of three months and no one case of maternal death was verified in the group. The deliveries were spontaneous and normal in all the patients. Only one case of fetal death occurred in consequence of a hemorragic shock. Comments are made on the clinical, laboratorial and prognostic features of chorea gravidarum, being particulary focused the physiopathogenic problem of this condtion.

  12. Heterochromatic banding patterns on chromosomes of twelve weevil species (Insecta, Coleoptera, Curculionoidea: Apionidae, Curculionidae). (United States)

    Holecová, Milada; Rozek, Maria; Lachowska, Dorota


    The C-banding patterns of twelve weevil species are presented. The obtained results confirm the existence of two groups of species: with a small or large amount of heterochromatin in the karyotype. The first group comprises seven species (Apionidae: Holotrichapion pisi; Curculionidae: Phyllobius urticae, Ph. pyri, Ph. maculicornis, Tanymecus palliatus, Larinodontes turbinatus, Cionus tuberculosus). In weevils with a small amount of heterochromatin, tiny grains on the nucleus in interphase are visible, afterwards in mitotic and meiotic prophase appearing as dark dots. The absence of C-bands does not indicate a lack of heterochromatin but heterochromatic regions are sometimes so small that the condensation is not visible during the cell cycle. The second group comprises five species (Otiorhynchus niger, O. morio, Polydrusus corruscus, Barypeithes chevrolati, Nedyus quadrimaculatus) which possess much larger heteropicnotic parts of chromosomes visible during all nuclear divisions. The species examined have paracentromeric C-bands on autosomes and the sex chromosome X, except for Otiorhynchus niger, which also has an intercalary bands on one pair of autososomes. All the species examined differ in the size of segments of constitutive heterochromatin. The y heterochromosome is dot-like and wholly euchromatic in all the studied species.

  13. In vitro antibacterial and antifungal activities of twelve sponges collected from the Anambas Islands, Indonesia

    Directory of Open Access Journals (Sweden)

    Masteria Yunovilsa Putra


    Full Text Available Objective: To evaluate antimicrobial activities in methanolic extracts of twelve sponges collected from the Anambas Islands, Indonesia. Methods: The antibacterial activity of methanolic extracts was tested against two Grampositive bacteria, viz. Bacillus subtilis (ATCC 6633 and Staphylococcus aureus (ATCC 25923, and two Gram-negative bacteria, viz. Eschericia coli (ATCC 25922 and Vibrio anguillarum (ATCC 19264 using the disk diffusion assay. The antifungal activity was similarly tested against Candida albicans (ATCC 10231 and Aspergillus niger (ATCC 16404. The minimum inhibitory concentrations of promising sponges extracts were determined by the microdilution technique. Results: All the sponge species in this study showed antimicrobial activities against at least one of the test strains. Antibacterial activities were observed in 66.7% of the sponges extracts, while 30.0% of the extracts exhibited antifungal activities. Among them, the extracts of the sponges Stylissa massa and Axinyssa sp. were the most active against four tested bacteria and the yeast Candida albicans. The sponge Theonella swinhoei and two species of Xestospongia also displayed significant activities against two fungal pathogens Candida albicans and Aspergillus niger. Conclusions: Antimicrobial activities were demonstrated in extracts from various marine sponges collected from the Anambas Islands, Indonesia. The most promising sponges among them were Stylissa massa and Axinyssa sp. This is the first report of antimicrobial activity in extracts of marine sponges from the Indonesian Anambas Islands.

  14. The SLUGGS Survey: Kinematics for over 2500 Globular Clusters in Twelve Early-type Galaxies

    CERN Document Server

    Pota, Vincenzo; Romanowsky, Aaron J; Brodie, Jean P; Spitler, Lee R; Strader, Jay; Foster, Caroline; Arnold, Jacob A; Benson, Andrew; Blom, Christina; Hargis, Jonathan R; Rhode, Katherine L; Usher, Christopher


    We present a spectro-photometric survey of 2522 extragalactic globular clusters (GCs) around twelve early-type galaxies, nine of which have not been published previously. Combining space-based and multi-colour wide field ground-based imaging, with spectra from the Keck DEIMOS instrument, we obtain an average of 160 GC radial velocities per galaxy, with a high velocity precision of 15 km/s per GC. After studying the photometric properties of the GC systems, such as their spatial and colour distributions, we focus on the kinematics of metal-poor (blue) and metal-rich (red) GC subpopulations to an average distance of ~8 effective radii from the galaxy centre. Our results show that for some systems the bimodality in GC colour is also present in GC kinematics. The kinematics of the red GC subpopulations are strongly coupled with the host galaxy stellar kinematics. The blue GC subpopulations are more dominated by random motions, especially in the outer regions, and decoupled from the red GCs. Peculiar GC kinematic ...

  15. Interaction and cooperative effort among scientific societies. Twelve years of COSCE. (United States)

    Martín, Nazario; Andradas, Carlos


    The evolution of knowledge and technology in recent decades has brought profound changes in science policy, not only in the countries but also in the supranational organizations. It has been necessary, therefore, to adapt the scientific institutions to new models in order to achieve a greater and better communication between them and the political counterparts responsible for defining the general framework of relations between science and society. The Federationon of Scientific Societies of Spain (COSCE, Confederación de Sociedades Científicas de España) was founded in October 2003 to respond to the urgent need to interact with the political institutions and foster a better orientation in the process of making decisions about the science policy. Currently COSCE consists of over 70 Spanish scientific societies and more than 40,000 scientists. During its twelve years of active life, COSCE has developed an intense work of awareness of the real situation of science in Spain by launching several initiatives (some of which have joined other organizations) or by joining initiatives proposed from other groups related to science both at the Spanish level and at the European and non-European scenarios. [Int Microbiol 18(4): 245-251 (2015)].

  16. Ecological conversion efficiency and its influencers in twelve species of fish in the Yellow Sea Ecosystem (United States)

    Tang, Qisheng; Guo, Xuewu; Sun, Yao; Zhang, Bo


    The ecological conversion efficiencies in twelve species of fish in the Yellow Sea Ecosystem, i.e., anchovy ( Engraulis japonicus), rednose anchovy ( Thrissa kammalensis), chub mackerel ( Scomber japonicus), halfbeak ( Hyporhamphus sajori), gizzard shad ( Konosirus punctatus), sand lance ( Ammodytes personatus), red seabream ( Pagrus major), black porgy ( Acanthopagrus schlegeli), black rockfish ( Sebastes schlegeli), finespot goby ( Chaeturichthys stigmatias), tiger puffer ( Takifugu rubripes), and fat greenling ( Hexagrammos otakii), were estimated through experiments conducted either in situ or in a laboratory. The ecological conversion efficiencies were significantly different among these species. As indicated, the food conversion efficiencies and the energy conversion efficiencies varied from 12.9% to 42.1% and from 12.7% to 43.0%, respectively. Water temperature and ration level are the main factors influencing the ecological conversion efficiencies of marine fish. The higher conversion efficiency of a given species in a natural ecosystem is acquired only under the moderate environment conditions. A negative relationship between ecological conversion efficiency and trophic level among ten species was observed. Such a relationship indicates that the ecological efficiency in the upper trophic levels would increase after fishing down marine food web in the Yellow Sea ecosystem.

  17. Alcoholics Anonymous and twelve-step recovery: a model based on social and cognitive neuroscience. (United States)

    Galanter, Marc


    In the course of achieving abstinence from alcohol, longstanding members of Alcoholics Anonymous (AA) typically experience a change in their addiction-related attitudes and behaviors. These changes are reflective of physiologically grounded mechanisms which can be investigated within the disciplines of social and cognitive neuroscience. This article is designed to examine recent findings associated with these disciplines that may shed light on the mechanisms underlying this change. Literature review and hypothesis development. Pertinent aspects of the neural impact of drugs of abuse are summarized. After this, research regarding specific brain sites, elucidated primarily by imaging techniques, is reviewed relative to the following: Mirroring and mentalizing are described in relation to experimentally modeled studies on empathy and mutuality, which may parallel the experiences of social interaction and influence on AA members. Integration and retrieval of memories acquired in a setting like AA are described, and are related to studies on storytelling, models of self-schema development, and value formation. A model for ascription to a Higher Power is presented. The phenomena associated with AA reflect greater complexity than the empirical studies on which this article is based, and certainly require further elucidation. Despite this substantial limitation in currently available findings, there is heuristic value in considering the relationship between the brain-based and clinical phenomena described here. There are opportunities for the study of neuroscientific correlates of Twelve-Step-based recovery, and these can potentially enhance our understanding of related clinical phenomena. © American Academy of Addiction Psychiatry.

  18. Fate of the conformal fixed point with twelve massless fermions and SU(3) gauge group (United States)

    Fodor, Zoltan; Holland, Kieran; Kuti, Julius; Mondal, Santanu; Nogradi, Daniel; Wong, Chik Him


    We report new results on the conformal properties of an important strongly coupled gauge theory, a building block of composite Higgs models beyond the Standard Model. With twelve massless fermions in the fundamental representation of the SU(3) color gauge group, an infrared fixed point (IRFP) of the β -function was recently reported in the theory [A. Cheng, A. Hasenfratz, Y. Liu, G. Petropoulos, and D. Schaich, J. High Energy Phys. 05 (2014) 137] with uncertainty in the location of the critical gauge coupling inside the narrow [6.0 fixed point and scale invariance in the theory with model-building implications. Using the exact same renormalization scheme as the previous study, we show that no fixed point of the β -function exists in the reported interval. Our findings eliminate the only seemingly credible evidence for conformal fixed point and scale invariance in the Nf=12 model whose infrared properties remain unresolved. The implications of the recently completed 5-loop QCD β -function for arbitrary flavor number are discussed with respect to our work.

  19. Chapter 8. Bending the Curve and Closing the Gap: Climate Justice and Public Health

    Directory of Open Access Journals (Sweden)

    Fonna Forman


    Full Text Available Climate change is projected to cause widespread and serious harm to public health and the environment upon which life depends, unraveling many of the health and social gains of the last century. The burden of harm will fall disproportionately on the poorest communities, both in the U.S. and globally, raising urgent issues of “climate justice”. In contrast, strategies for climate action, including those of an institutional, and cultural nature, have the potential to improve quality of life for everyone. This chapter examines the social dimensions of building carbon neutral societies, with an emphasis on producing behavioral shifts, among both the most and the least advantaged populations. In support of Bending the Curve solutions 2 and 3, the case studies offered in this chapter rely not only on innovations in technology and policy, but innovations in attitudinal and behavioral change as well, focused on coordinated public communication and education (Solution 2, as well as new platforms for collaborating, where leaders across sectors can convene to tackle concrete problems (Solution 3.

  20. Chapter D. The Loma Prieta, California, Earthquake of October 17, 1989 - Aftershocks and Postseismic Effects (United States)

    Reasenberg, Paul A.


    While the damaging effects of the earthquake represent a significant social setback and economic loss, the geophysical effects have produced a wealth of data that have provided important insights into the structure and mechanics of the San Andreas Fault system. Generally, the period after a large earthquake is vitally important to monitor. During this part of the seismic cycle, the primary fault and the surrounding faults, rock bodies, and crustal fluids rapidly readjust in response to the earthquake's sudden movement. Geophysical measurements made at this time can provide unique information about fundamental properties of the fault zone, including its state of stress and the geometry and frictional/rheological properties of the faults within it. Because postseismic readjustments are rapid compared with corresponding changes occurring in the preseismic period, the amount and rate of information that is available during the postseismic period is relatively high. From a geophysical viewpoint, the occurrence of the Loma Prieta earthquake in a section of the San Andreas fault zone that is surrounded by multiple and extensive geophysical monitoring networks has produced nothing less than a scientific bonanza. The reports assembled in this chapter collectively examine available geophysical observations made before and after the earthquake and model the earthquake's principal postseismic effects. The chapter covers four broad categories of postseismic effect: (1) aftershocks; (2) postseismic fault movements; (3) postseismic surface deformation; and (4) changes in electrical conductivity and crustal fluids.

  1. Medical Problems Related to Altitude in: Human Performance Physiology and Environmental Medicine at Terrestrial Extremes. Chapter 14, (United States)


    relation with HACE or HAPE. The diagnosis is based on history and physical findings. The differential diagnosis includes cardiogenic edema and allergic...acute mountain sickness, high altitude cerebral edema , high altitude pulmonary edema , high altitude retinal hemorrhages, qeneralizellpripheral edema ...reentry pulmonary edema , chronic moUntai n II n ~rp, E, 19. ABSTRACT (Continue on reverse if necessary and identify by block number) .This chapter

  2. Improving Comparability Of Survey Results Through Ex-Post Harmonisation A Case Study With Twelve European National Travel Surveys

    DEFF Research Database (Denmark)

    Christensen, Linda; Hubert, Jean-Paul; Järvi, Tuuli

    that reflect behavioural differences rather than methodological ones, in the context of the COST Action SHANTI (Survey Harmonisation with New Technologies Improvement, TUD0804) an ex-post harmonisation approach was developed using microdata from twelve European NTS’s. The paper presents both concept and basic...

  3. Chapter 10.3: Reliability and Durability of PV Modules

    Energy Technology Data Exchange (ETDEWEB)

    Kurtz, Sarah


    Each year the world invests tens of billions of dollars or euros in PV systems with the expectation that these systems will last approximately 25 years. Although the disciplines of reliability, quality, and service life prediction have been well established for numerous products, a full understanding of these is currently challenging for PV modules because the desired service lifetimes are decades, preventing direct verification of lifetime predictions. A number of excellent reviews can be found in the literature summarizing the types of failures that are commonly observed for PV modules. This chapter discusses key failure/degradation mechanisms selected to highlight how the kinetics of failure rates can and cannot be confidently predicted. For EVA-encapsulated modules, corrosion is observed to follow delamination, which then allows water droplets to directly contact the metallization. Extended test protocols such as Qualification Plus were created to address the known problems while standards groups update standard tests through the consensus process.

  4. Chapter 3 – VPPD-Lab: The Chemical Product Simulator

    DEFF Research Database (Denmark)

    Kalakul, Sawitree; Cignitti, Stefano; Zhang, L.


    Computer-aided methods and tools for current and future product–process design and development need to manage problems requiring efficient handling of models, data, and knowledge from different sources and at different times and size scales. In this chapter, a systematic model-based framework......, such as single molecule products, formulations, blends, emulsions, and devices; and (2) to create new product design templates when the needed template for a desired product is not available. VPPD-Lab employs a suite of algorithms (such as database search, molecular and mixture blend design) and toolboxes (such...... lotion design. Through these case studies, the use of design templates, associated workflows (methods), data flows (software integration), and solution strategies (database and tools) are highlighted....

  5. Introduction to physical properties and elasticity models: Chapter 20 (United States)

    Dvorkin, Jack; Helgerud, Michael B.; Waite, William F.; Kirby, Stephen H.; Nur, Amos


    Estimating the in situ methane hydrate volume from seismic surveys requires knowledge of the rock physics relations between wave speeds and elastic moduli in hydrate/sediment mixtures. The elastic moduli of hydrate/sediment mixtures depend on the elastic properties of the individual sedimentary particles and the manner in which they are arranged. In this chapter, we present some rock physics data currently available from literature. The unreferenced values in Table I were not measured directly, but were derived from other values in Tables I and II using standard relationships between elastic properties for homogeneous, isotropic material. These derivations allow us to extend the list of physical property estimates, but at the expense of introducing uncertainties due to combining property values measured under different physical conditions. This is most apparent in the case of structure II (sII) hydrate for which very few physical properties have been measured under identical conditions.

  6. Chapter 11: Marine and Hydrokinetic Power Generation and Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Muljadi, Eduard; Yu, Yi-Hsiang


    Marine and hydrokinetic (MHK) power generation is a relatively new type of renewable generation. Predecessors such as wind power generation, hydropower plant generation, geothermal generation, photovoltaic generation, and solar thermal generation have gained a lot of attention because of their successful implementation. The successful integration of renewable generation into the electric power grid has energized the power system global communities to take the lessons learned, innovations, and market structure to focus on the large potential of MHK to also contribute to the pool of renewable energy generation. This chapter covers the broad spectrum of MHK generation. The state-of-the-art power takeoff methods will be discussed. Types of electrical generators will be presented, and the options for implementation will be presented.

  7. Chapter 3: Science and Pathways for Bending the Curve

    Directory of Open Access Journals (Sweden)

    William D. Collins


    Full Text Available Greenhouse gas emissions from fossil fuel combustion and land use are changing the radiative budget of the Earth and changing its climate. The negative impacts of this climate change on natural and human systems are already emergent. The solution is to eliminate greenhouse gas emissions altogether as soon as possible, but the rate at which these emissions can decrease is limited by human reliance on fossil fuels for energy and the infrastructural, socio-economic, and behavioral inertia of current systems around the world. In this chapter, we discuss the physical impacts as well as the many challenges and obstacles to ‘bending the curve’, and provide a framework of possible solutions.

  8. Chapter Three - Weed Dynamics and Management in Wheat

    DEFF Research Database (Denmark)

    Jabran, Khawar; Mahmood, Khalid; Melander, Bo


    pest of wheat causing in total 24% losses in wheat grain yield. In this chapter, we discuss the (i) weed flora in different wheat-growing regions of world; (ii) the yield losses caused by weeds in wheat; (iii) the preventive and cultural options for weed management; (iv) physical weed control; (v......) chemical weed control; and (vi) integrated weed management strategy in wheat. A critical analysis of recent literature indicated that broadleaved weeds are the most common group of weeds in wheat fields followed by grass weeds, while sedges were rarely noted in wheat fields. Across the globe, the most...... important weeds in wheat fields were Avena fatua L., Chenopodium album L., Phalaris minor Retz., Galium aparine L., Stellaria media (L.) Vill., and Veronica persica Poir., respectively. Adoption of wise weed management strategies may help control weeds and avoid yield losses. Both preventive measures...

  9. Relative peripheral refraction in children: twelve-month changes in eyes with different ametropias. (United States)

    Lee, Tsui-Tsui; Cho, Pauline


    To determine the peripheral refraction of children with different types of ametropias and to evaluate the relationship between central refractive changes, baseline relative peripheral refraction (RPR) and changes in RPR over a 12-month monitoring period. Cycloplegic central and peripheral refraction were performed biannually on the right eyes of children aged 6-9 for 12 months, using an open-view autorefractor. Peripheral refraction were measured along 10°, 20° and 30° from central fixation in both nasal and temporal fields. Refractive data were transposed into M, J0 and J45 vectors for analyses. RPR was determined by subtracting the central measurement from each peripheral measurement. Hyperopic eyes showed relative peripheral myopia while myopic eyes had relative hyperopia across the central 60° horizontal field at baseline. Emmetropic eyes had relative myopia within but showed relative hyperopia beyond the central 30° field. However, there was no significant correlation between central refractive changes and baseline RPR or between changes in central refraction and RPR over twelve months in any refractive groups. Correlations between changes in PR and central myopic shift were found mainly in the nasal field in different groups. In the subgroup analysis on the initially emmetropic and the initially myopic groups, the subgroups with faster myopic progression did not have significantly different RPR from the subgroups with slower progression. The RPR pattern of the initially emmetropic and the initially myopic groups became more asymmetric at the end of the study period with a larger increase in relative hyperopia in the temporal field. RPR patterns were different among hyperopic, emmetropic and myopic eyes. However, baseline RPR and changes in RPR cannot predict changes in central refraction over time. Our results did not provide evidence to support the hypothesis of RPR as a causative factor for myopic central refractive changes in children. Ophthalmic

  10. Computational study of the structural and vibrational properties of ten and twelve vertex closo-carboranes

    Energy Technology Data Exchange (ETDEWEB)

    Salam, A.; Deleuze, M.S.; Francois, J.-P


    Calculations using ab initio Hartree-Fock and Density Functional theories, the latter employing the B3LYP functional, in combination with a number of large standard basis sets ranging from 6-31G** to cc-pVDZ, have been performed on a series of ten and twelve vertex closo-carborane isomer species. Results obtained for optimized structural parameters and molecular properties are presented for 1,2-, 1,6- and 1,10-C{sub 2}B{sub 8}H{sub 10} and 1,2-, 1,7- and 1,12-C{sub 2}B{sub 10}H{sub 12} and compared, where possible, with both earlier theoretical data and experiment. Irrespective of the model chemistry chosen, the para-isomer in each class of carborane cluster is found to be the most stable species, corresponding to a structure in which the cage carbon atoms are positioned at diametrically opposed ends of the respective polyhedron. Boron-hydrogen and carbon-hydrogen bond lengths are found to change little on going from isomers of one particular cage size to another, supporting analogous conclusions previously established for small closo-carborane cages possessing five, six and seven vertices. The calculated vibrational spectra of the isomers of both decacarborane and dodecacarborane are seen to be similar to each other and reflect a high degree of rigidity within each cluster. Key polyhedral skeletal breathing modes along with characteristic boron-hydrogen and carbon-hydrogen stretching frequencies are identified in the spectra and compared with experiment. Thermochemical data relating to each species are also analyzed.

  11. Indifference to pain syndrome in a twelve-year-old boy (case report

    Directory of Open Access Journals (Sweden)

    Baghdadi T


    Full Text Available Background: People vary greatly in their response to painful stimuli, from those with a low pain threshold to those with indifference to pain. However, insensitivity to pain is a rare disorder, characterized by the lack of usual subjective and objective responses to noxious stimuli. Patients who have congenital indifference to pain sustain painless injuries beginning in infancy, but have sensory responses that are otherwise normal on examination. Perception of passive movement, joint position, and vibration is normal in these patients, as are tactile thresholds and light touch perception. Case report: A twelve-year-old boy was admitted to the hospital for a painless deformity, degeneration in both knees and a neglected femoral neck fracture that was inappropriately painless. Further examination revealed normal sensory responses, perception of passive movement, joint position, vibration tactile thresholds and light touch perception. Spinal cord and brain MRI were normal as was the electromyography and nerve conduction velocity (EMG/NCV examination. There was no positive family history for this disorder. Conclusion: The deficits present in the different pain insensitivity syndromes provide insight into the complex anatomical and physiological nature of pain perception. Reports on pain asymbolia, in which pain is perceived but does not cause suffering, and related cortical conditions illustrate that there can be losses that independently involve either the sensory-discriminative component or the affective-motivational component of pain perception, thus highlighting their different anatomical localization. The paucity of experience with this entity and the resultant diagnostic problems, the severity of the associated disabling arthropathy and underscore the importance of this case report of indifference to pain.

  12. Removal of trace level amounts of twelve sulfonamides from drinking water by UV-activated peroxymonosulfate. (United States)

    Cui, Changzheng; Jin, Lei; Jiang, Lei; Han, Qi; Lin, Kuangfei; Lu, Shuguang; Zhang, Dong; Cao, Guomin


    Trace levels of residual antibiotics in drinking water may threaten public health and become a serious problem in modern society. In this work, we investigated the degradation of twelve sulfonamides (SAs) at environmentally relevant trace level concentrations by three different methods: ultraviolet (UV) photolysis, peroxymonosulfate (PMS) oxidation, and UV-activated PMS (UV/PMS). Sulfaguanidine, sulfadiazine, sulfamerazine, sulfamethazine, sulfathiazole, sulfamethoxydiazine, and sulfadimethoxine were be effectively removed by direct UV photolysis and PMS oxidation. However, sulfanilamide, sulfamethizole, sulfamethoxazole, sulfisoxazole, and sulfachloropyridazine were not completely degraded, despite prolonging the UV irradiation time to 30min or increasing the PMS concentration to 5.0mg·L(-1). UV/PMS provided more thorough elimination of SAs, as demonstrated by the complete removal of 200ng·L(-1) of all SAs within 5min at an initial PMS concentration of 1.0mg·L(-1). UV/PMS promoted SA decomposition more efficiently than UV photolysis or PMS oxidation alone. Bicarbonate concentration and pH had a negligible effect on SA degradation by UV/PMS. However, humic acid retarded the process. Removal of 200ng·L(-1) of each SA from a sample of sand-filtered effluent from a drinking water treatment plant (DWTPs) was quickly and completely achieved by UV/PMS. Meanwhile, about 41% of the total organic carbon (TOC) was eliminated. Scavenging experiments showed that sulfate radical (SO4(-)) was the predominant species involved in the degradation. It is concluded that UV/PMS is a rapid and efficient method for removing trace-level SAs from drinking water. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Characterizing gene-gene interactions in a statistical epistasis network of twelve candidate genes for obesity. (United States)

    De, Rishika; Hu, Ting; Moore, Jason H; Gilbert-Diamond, Diane


    Recent findings have reemphasized the importance of epistasis, or gene-gene interactions, as a contributing factor to the unexplained heritability of obesity. Network-based methods such as statistical epistasis networks (SEN), present an intuitive framework to address the computational challenge of studying pairwise interactions between thousands of genetic variants. In this study, we aimed to analyze pairwise interactions that are associated with Body Mass Index (BMI) between SNPs from twelve genes robustly associated with obesity (BDNF, ETV5, FAIM2, FTO, GNPDA2, KCTD15, MC4R, MTCH2, NEGR1, SEC16B, SH2B1, and TMEM18). We used information gain measures to identify all SNP-SNP interactions among and between these genes that were related to obesity (BMI > 30 kg/m(2)) within the Framingham Heart Study Cohort; interactions exceeding a certain threshold were used to build an SEN. We also quantified whether interactions tend to occur more between SNPs from the same gene (dyadicity) or between SNPs from different genes (heterophilicity). We identified a highly connected SEN of 709 SNPs and 1241 SNP-SNP interactions. Combining the SEN framework with dyadicity and heterophilicity analyses, we found 1 dyadic gene (TMEM18, P-value = 0.047) and 3 heterophilic genes (KCTD15, P-value = 0.045; SH2B1, P-value = 0.003; and TMEM18, P-value = 0.001). We also identified a lncRNA SNP (rs4358154) as a key node within the SEN using multiple network measures. This study presents an analytical framework to characterize the global landscape of genetic interactions from genome-wide arrays and also to discover nodes of potential biological significance within the identified network.

  14. Thermal environment in eight low-energy and twelve conventional Finnish houses. (United States)

    Kähkönen, Erkki; Salmi, Kari; Holopainen, Rauno; Pasanen, Pertti; Reijula, Kari


    We assessed the thermal environment of eight recently built low-energy houses and twelve conventional Finnish houses. We monitored living room, bedroom and outdoor air temperatures and room air relative humidity from June 2012 to September 2013. Perceived thermal environment was evaluated using a questionnaire survey during the heating, cooling and interim seasons. We compared the measured and perceived thermal environments of the low-energy and conventional houses. The mean air temperature was 22.8 °C (21.9-23.8 °C) in the low-energy houses, and 23.3 °C (21.4-26.5 °C) in the conventional houses during the summer (1. June 2013-31. August 2013). In the winter (1. December 2012-28. February 2013), the mean air temperature was 21.3 °C (19.8-22.5 °C) in the low-energy houses, and 21.6 °C (18.1-26.4 °C) in the conventional houses. The variation of the air temperature was less in the low-energy houses than that in the conventional houses. In addition, the occupants were on average slightly more satisfied with the indoor environment in the low-energy houses. However, there was no statistically significant difference between the mean air temperature and relative humidity of the low-energy and conventional houses. Our measurements and surveys showed that a good thermal environment can be achieved in both types of houses.

  15. Phytochemical screening of twelve species of phytoplankton isolated from Arabian Sea coast

    Directory of Open Access Journals (Sweden)

    Sushanth Vishwanath Rai


    Full Text Available Objective: To analyze the phytochemicals in twelve species of marine phytoplankton. Methods: Total phenolic content of methanol extract was estimated by the Folin-Ciocalteu method. Total flavonoid content of the methanol extarct was determined by aluminium chloride method. Chlorophylls, β-carotene and astaxanthin were estimated by acetone extraction method. Vitamin C was determined by dinitrophenyl-hydrazine method. Phycobiliproteins such as allophycocyanin, phycocyanin and phycoerythrin in the aqueous extracts were determined. Results: Total phenolics varied from 5.41 mg gallic acid equivalents/g dry weight (DW in Phormidium corium (P. corium to 17.37 mg gallic acid equivalents/g DW in Oscillatoria fremyii (O. fremyii. Total flavonoids ranged between 0.74 mg quercetin equivalent/g DW in P. corium and 9.87 mg quercetin equivalent/g DW in Nannochloropsis oceanica. Chlorophyll-a pigment was high in Chaetoceros calcitrans (C. calcitrans (15.51 mg/g DW and low in P. corium (1.08 mg/g DW. Chlorophyll-c ranged between 0.07 mg/g DW in Nannochloropsis oceanica and 4.62 mg/g DW in C. calcitrans. High contents of β-carotene and astaxanthin were found in C. calcitrans and low in P. corium which ranged from 0.33 to 10.03 mg/g DW and 0.18 to 3.85 mg/g DW, respectively. Vitamin C content varied from 0.50 mg/g DW in C. calcitrans to 1.51 mg/g DW in Phormidium tenue. O. fremyii showed highest total phycobiliproteins of 317.05 mg/g DW. High contents of allophycocyanin and phycocyanin were found in O. fremyii, whereas high contents of phycoerythrin were found in Oscillatoria sancta. All the three phycobiliproteins were low in Chroococcus turgidus. Conclusions: Marine phytoplankton are one of the natural sources providing novel biologically active compounds with potential for pharmaceutical applications.

  16. Proceedings, Annual Meeting, Western Canada Chapter, American Society for Information Science (Third, Banff School of Fine Arts, October 3,4,5, 1971). (United States)

    Calgary Univ. (Alberta).

    The proceedings contain papers given by the members of the chapter who come from both the University and Business environments. Some operational indexing, bibliographic, SDI and Retrospective Search Systems which include CAN/SDI, Compendex, TEXT-PAC, SIS II & III, KWOC and FAMULUS are discussed. Also included are papers on two projects conducted…

  17. Chapter 5: Network biology approach to complex diseases.

    Directory of Open Access Journals (Sweden)

    Dong-Yeon Cho

    Full Text Available Complex diseases are caused by a combination of genetic and environmental factors. Uncovering the molecular pathways through which genetic factors affect a phenotype is always difficult, but in the case of complex diseases this is further complicated since genetic factors in affected individuals might be different. In recent years, systems biology approaches and, more specifically, network based approaches emerged as powerful tools for studying complex diseases. These approaches are often built on the knowledge of physical or functional interactions between molecules which are usually represented as an interaction network. An interaction network not only reports the binary relationships between individual nodes but also encodes hidden higher level organization of cellular communication. Computational biologists were challenged with the task of uncovering this organization and utilizing it for the understanding of disease complexity, which prompted rich and diverse algorithmic approaches to be proposed. We start this chapter with a description of the general characteristics of complex diseases followed by a brief introduction to physical and functional networks. Next we will show how these networks are used to leverage genotype, gene expression, and other types of data to identify dysregulated pathways, infer the relationships between genotype and phenotype, and explain disease heterogeneity. We group the methods by common underlying principles and first provide a high level description of the principles followed by more specific examples. We hope that this chapter will give readers an appreciation for the wealth of algorithmic techniques that have been developed for the purpose of studying complex diseases as well as insight into their strengths and limitations.

  18. Chapter 50: How to Build Client Applications with VOClient (United States)

    Tody, D.; Fitzpatrick, M. J.

    VOClient is a software facility which runs locally on a user's computer, implementing the client side of the major VO data-related services. VOClient handles the details required to connect to the VO, execute remote services, and discover and download data. The downloaded data is cached locally for high performance data access, and a high level API is provided to gain access to the data at various levels. Bindings of the VOClient functionality are provided for most major compiled and scripting languages and astronomical environments. VOClient currently supports VO registry queries, plus the simple cone search (SCS) and simple image access (SIA) interfaces for access to catalog and image data. Support for access to spectral data is expected in mid-2007, and support for other forms of astronomical data will be added as standard VO data access layer (DAL) protocols for additional types of data become available. An overview of the VOClient facility is given in Chapter 22. In this chapter we illustrate how to use VOClient to implement simple cone search and simple image access client applications. Any application which uses VOClient will follow the same pattern as the examples shown here, as all data interfaces share the same form. To illustrate the multi-language nature of VOClient, we will implement our sample programs in both Java and C; however, these sample programs could be implemented in any of the supported languages with the same results. Translation to other languages is straightforward, as the VOClient API is much the same in all supported languages.

  19. Phytochemical screening of twelve species of phytoplankton isolated from Arabian Sea coast

    Institute of Scientific and Technical Information of China (English)

    Sushanth Vishwanath Rai; Madaiah Rajashekhar


    Objective:To analyze the phytochemicals in twelve species of marine phytoplankton. Methods: Total phenolic content of methanol extract was estimated by the Folin-Ciocalteu method. Total flavonoid content of the methanol extarct was determined by aluminium chloride method. Chlorophylls,β-carotene and astaxanthin were estimated by acetone extraction method. Vitamin C was determined by dinitrophenyl-hydrazine method. Phycobiliproteins such as allophycocyanin, phycocyanin and phycoerythrin in the aqueous extracts were determined. Results: Total phenolics varied from 5.41 mg gallic acid equivalents/g dry weight (DW) in Phormidium corium (P. corium) to 17.37 mg gallic acid equivalents/g DW inOscillatoria fremyii(O. fremyii). Total flavonoids ranged between 0.74 mg quercetin equivalent/g DW inP. corium and 9.87 mg quercetin equivalent/g DW inNannochloropsis oceanica. Chlorophyll-a pigment was high inChaetoceros calcitrans(C. calcitrans)(15.51 mg/g DW) and low inP. corium (1.08 mg/g DW). Chlorophyll-c ranged between 0.07 mg/g DW inNannochloropsis oceanica and 4.62 mg/g DW inC. calcitrans. High contents ofβ-carotene and astaxanthin were found inC. calcitrans and low inP. corium which ranged from 0.33 to 10.03 mg/g DW and 0.18 to 3.85 mg/g DW, respectively. Vitamin C content varied from 0.50 mg/g DW inC. calcitrans to 1.51 mg/g DW inPhormidium tenue.O. fremyii showed highest total phycobiliproteins of 317.05 mg/g DW. High contents of allophycocyanin and phycocyanin were found inO. fremyii, whereas high contents of phycoerythrin were found inOscillatoria sancta. All the three phycobiliproteins were low inChroococcus turgidus. Conclusions: Marine phytoplankton are one of the natural sources providing novel biologically active compounds with potential for pharmaceutical applications.

  20. Molecular phylogenetic systematics of twelve species of Acipenseriformes based on mtDNA ND4L -ND4 gene sequence analysis

    Institute of Scientific and Technical Information of China (English)

    张四明; 张亚平; 郑向忠; 陈永久; 邓怀; 汪登强; 危起伟; 张云武; 聂龙; 吴清江


    Acipenseriformes is an endangered primitive fish group, which occupies a special place in the history of ideas concerning fish evolution, even in vertebrate evolution. However, the classification and evolution of the fishes have been debated. The mitochondrial DMA (mtDNA) ND4L and partial A7D4 genes were first sequenced in twelve species of the order Acipenseriformes, including endemic Chinese species. The following points were drawn from DNA sequences analysis: (i) the two species of Huso can be ascribed to Acipenser; (ii) A. dabryanus is the mostly closely related to A. sinensis, and most likely the landlocked form of A. sinensis; (iii) genus Acipenser in trans-Pacific region might have a common origin; (iv) mtDNA ND4L and ND4 genes are the ideal genetic markers for phylogenetic analysis of the order Acipenseriformes.

  1. Molecular phylogenetic systematics of twelve species of Acipenseriformes based on mtDNA ND4L -ND4 gene sequence analysis

    Institute of Scientific and Technical Information of China (English)


    Acipenseriformes is an endangered primitive fish group, which occupies a special place in the history of ideas concerning fish evolution, even in vertebrate evolution. However, the classification and evolution of the fishes have been debated. The mitochondrial DNA (mtDNA) ND4L and partial ND4 genes were first sequenced in twelve species of the order Acipenseriformes, including endemic Chinese species. The following points were drawn from DNA sequences analysis: (i) the two species of Huso can be ascribed to Acipenser; (ii) A. dabryanus is the mostly closely related to A. sinensis, and most likely the landlocked form of A. sinensis; (iii) genus Acipenser in trans-Pacific region might have a common origin; (iv) mtDNA ND4L and ND4 genes are the ideal genetic markers for phylogenetic analysis of the order Acipenseriformes.

  2. Analyses of Twelve New Whole Genome Sequences of Cassava Brown Streak Viruses and Ugandan Cassava Brown Streak Viruses from East Africa: Diversity, Supercomputing and Evidence for Further Speciation.

    Directory of Open Access Journals (Sweden)

    Joseph Ndunguru

    Full Text Available Cassava brown streak disease is caused by two devastating viruses, Cassava brown streak virus (CBSV and Ugandan cassava brown streak virus (UCBSV which are frequently found infecting cassava, one of sub-Saharan Africa's most important staple food crops. Each year these viruses cause losses of up to $100 million USD and can leave entire families without their primary food source, for an entire year. Twelve new whole genomes, including seven of CBSV and five of UCBSV were uncovered in this research, doubling the genomic sequences available in the public domain for these viruses. These new sequences disprove the assumption that the viruses are limited by agro-ecological zones, show that current diagnostic primers are insufficient to provide confident diagnosis of these viruses and give rise to the possibility that there may be as many as four distinct species of virus. Utilizing NGS sequencing technologies and proper phylogenetic practices will rapidly increase the solution to sustainable cassava production.

  3. Age Distribution of Influenza Like Illness Cases during Post-Pandemic A(H3N2): Comparison with the Twelve Previous Seasons, in France (United States)

    Turbelin, Clément; Souty, Cécile; Pelat, Camille; Hanslik, Thomas; Sarazin, Marianne; Blanchon, Thierry; Falchi, Alessandra


    In France, the 2011–2012 influenza epidemic was characterized by the circulation of antigenically drifted influenza A(H3N2) viruses and by an increased disease severity and mortality among the elderly, with respect to the A(H1N1)pdm09 pandemic and post-pandemic outbreaks. Whether the epidemiology of influenza in France differed between the 2011–2012 epidemic and the previous outbreaks is unclear. Here, we analyse the age distribution of influenza like illness (ILI) cases attended in general practice during the 2011–2012 epidemic, and compare it with that of the twelve previous epidemic seasons. Influenza like illness data were obtained through a nationwide surveillance system based on sentinel general practitioners. Vaccine effectiveness was also estimated. The estimated number of ILI cases attended in general practice during the 2011–2012 was lower than that of the past twelve epidemics. The age distribution was characteristic of previous A(H3N2)-dominated outbreaks: school-age children were relatively spared compared to epidemics (co-)dominated by A(H1N1) and/or B viruses (including the 2009 pandemic and post-pandemic outbreaks), while the proportion of adults over 30 year-old was higher. The estimated vaccine effectiveness (54%, 95% CI (48, 60)) was in the lower range for A(H3N2) epidemics. In conclusion, the age distribution of ILI cases attended in general practice seems to be not different between the A(H3N2) pre-pandemic and post-pandemic epidemics. Future researches including a more important number of ILI epidemics and confirmed virological data of influenza and other respiratory pathogens are necessary to confirm these results. PMID:23755294

  4. Sliding and Rocking of Unanchored Components and Structures: Chapter 7.6 ASCE 4 Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    S. R. Jensen


    Chapter 7.6 of ASCE 4-Rev 2, Seismic Analysis of Safety-Related Nuclear Structures: Standard and Commentary, provides updated guidance for analysis of rocking and sliding of unanchored structures and components subjected to seismic load. This guidance includes provisions both for simplified approximate energy-based approaches, and for detailed probabilistic time history analysis using nonlinear methods. Factors to be applied to the analytical results are also provided with the intent of ensuring achievement of the 80% non-exceedence probability target of the standard. The present paper surveys the published literature supporting these provisions. The results of available testing and analysis are compared to results produced by both simplified and probabilistic approaches. In addition, adequacy of the standard's provisions for analysis methods and factors is assessed. A comparison is made between the achieved level of conservatism and the standard's non-exceedence probability target.

  5. Biological soil crusts as an organizing principle in drylands: Chapter 1 (United States)

    Belnap, Jayne; Weber, Bettina; Büdel, Burkhard; Weber, Bettina; Buedel, Burkhard; Belnap, Jayne


    Biological soil crusts (biocrusts) have been present on Earth’s terrestrial surfaces for billions of years. They are a critical part of ecosystem processes in dryland regions, as they cover most of the soil surface and thus mediate almost all inputs and outputs from soils in these areas. There are many intriguing, but understudied, roles these communities may play in drylands. These include their function in nutrient capture and transformation, influence on the movement and distribution of nutrients and water within dryland soils, ability to structure vascular plant communities, role in creating biodiversity hotspots, and the possibility that they can be used as indicators of soil health. There are still many fascinating aspects of these communities that need study, and we hope that this chapter will facilitate such efforts.

  6. Chapter 8: Pyrolysis Mechanisms of Lignin Model Compounds Using a Heated Micro-Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Robichaud, David J.; Nimlos, Mark R.; Ellison, G. Barney


    Lignin is an important component of biomass, and the decomposition of its thermal deconstruction products is important in pyrolysis and gasification. In this chapter, we investigate the unimolecular pyrolysis chemistry through the use of singly and doubly substituted benzene molecules that are model compounds representative of lignin and its primary pyrolysis products. These model compounds are decomposed in a heated micro-reactor, and the products, including radicals and unstable intermediates, are measured using photoionization mass spectrometry and matrix isolation infrared spectroscopy. We show that the unimolecular chemistry can yield insight into the initial decomposition of these species. At pyrolysis and gasification severities, singly substituted benzenes typically undergo bond scission and elimination reactions to form radicals. Some require radical-driven chain reactions. For doubly substituted benzenes, proximity effects of the substituents can change the reaction pathways.

  7. A retrospective evaluation of the quality of malaria case management at twelve health facilities in four districts in Zambia

    Institute of Scientific and Technical Information of China (English)

    Pascalina Chanda-Kapata; Emmanuel Chanda; Freddie Masaninga; Annette Habluetzel; Felix Masiye; Ibrahima Soce Fall


    Objective: To establish the appropriateness of malaria case management at health facility level in four districts in Zambia. Methods: This study was a retrospective evaluation of the quality of malaria case management at health facilities in four districts conveniently sampled to represent both urban and rural settings in different epidemiological zones and health facility coverage. The review period was from January to December 2008. The sample included twelve lower level health facilities from four districts. The Pearson Chi-square test was used to identify characteristics which affected the quality of case management.Results:Out of 4891 suspected malaria cases recorded at the 12 health facilities, more than 80% of the patients had a temperature taken to establish their fever status. About 67% (CI95 66.1-68.7) were tested for parasitemia by either rapid diagnostic test or microscopy, whereas the remaining 22.5% (CI95 21.3.1-23.7) were not subjected to any malaria test. Of the 2247 malaria cases reported (complicated and uncomplicated), 71% were parasitologically confirmed while 29% were clinically diagnosed (unconfirmed). About 56% (CI95 53.9-58.1) of the malaria cases reported were treated with artemether-lumefantrine (AL), 35% (CI95 33.1-37.0) with sulphadoxine-pyrimethamine, 8% (CI95 6.9-9.2) with quinine and 1% did not receive any anti-malarial. Approximately 30% of patients WHO were found negative for malaria parasites were still prescribed an anti-malarial, contrary to the guidelines. There were marked inter-district variations in the proportion of patients in WHOm a diagnostic tool was used, and in the choice of anti-malarials for the treatment of malaria confirmed cases. Association between health worker characteristics and quality of case malaria management showed that nurses performed better than environmental health technicians and clinical officers on the decision whether to use the rapid diagnostic test or not. Gender, in service training on malaria

  8. Chapter 20: neurological illustration from photography to cinematography. (United States)

    Aubert, Geneviève


    This chapter explores iconography in neurology from the birth of photography up to the early medical applications of cinematography before 1914. The important visual part of neurological diagnosis explains why these techniques were adopted very early by neurologists. Duchenne published the first medical book illustrated with photographs of patients. The first and most famous photographic laboratory was created in Charcot's department, at the Salpêtrière in Paris, under the direction of Albert Londe. Londe published the first book dedicated to medical photography. The physiologist Marey and the photographer Muybridge, in association with neurologists, played key roles in the development of chronophotography and cinematography. Germany was the first country to welcome cinematography in a neurology department. Independently, neurologists began to film patients in other countries in Europe and in America. In 1905, Arthur Van Gehuchten (1861-1914), Belgian anatomist and neurologist, began systematically to film neurologic patients, with the intention of building up a complete neurological iconographic collection. This collection has survived and has been restored in the laboratory of the Royal Belgian Film Archive where the films are now safely stored in their vaults.

  9. Chapter 4: neurology in the Bible and the Talmud. (United States)

    Feinsod, Moshe


    The Bible, a major pillar of Western Civilization consists of Hebrew Scriptures, assembled over a millennium and accepted as of divine origin. The Talmud is a compendium of Jewish laws, covering every possible aspect of life, analyzed in depth from 200 BCE to 600 CE, becoming the foundation of Jewish existence. The all-encompassing character of the books provides numerous medical problems and observations that appear in various connotations. When in need to clarify various legal dilemmas, the Talmudic sages displayed astoundingly accurate anatomical knowledge and were pioneers in clinical-pathological correlations. The descriptions of "neurological" events in the Bible are very precise but show no evidence of neurological knowledge. Those reported in the various tractates of the Talmud are evidence of a substantial medical knowledge, marked by Hellenistic influence. Subjects such as head and spinal injuries, epilepsy, handedness neuralgias aphasia tinnitus and tremor were discussed in depth. This chapter is an updated collection of the studies, extracting observations and discussions of neurological manifestations from the ancient texts.

  10. Applied Space Systems Engineering. Chapter 17; Manage Technical Data (United States)

    Kent, Peter


    Effective space systems engineering (SSE) is conducted in a fully electronic manner. Competitive hardware, software, and system designs are created in a totally digital environment that enables rapid product design and manufacturing cycles, as well as a multitude of techniques such as modeling, simulation, and lean manufacturing that significantly reduce the lifecycle cost of systems. Because the SSE lifecycle depends on the digital environment, managing the enormous volumes of technical data needed to describe, build, deploy, and operate systems is a critical factor in the success of a project. This chapter presents the key aspects of Technical Data Management (TDM) within the SSE process. It is written from the perspective of the System Engineer tasked with establishing the TDM process and infrastructure for a major project. Additional perspectives are reflected from the point of view of the engineers on the project who work within the digital engineering environment established by the TDM toolset and infrastructure, and from the point of view of the contactors who interface via the TDM infrastructure. Table 17.1 lists the TDM process as it relates to SSE.

  11. CHAPTER 6. Biomimetic Materials for Efficient Atmospheric Water Collection

    KAUST Repository

    Zhang, Lianbin


    Water scarcity is a severe problem in semi-arid desert regions, land-scarce countries and in countries with high levels of economic activity. In these regions, the collection of atmospheric water - for example, fog - is recognized as an important method of providing water. In nature, through millions of year evolution, some animals and plants in many of the arid regions have developed unique and highly efficient systems with delicate microstructures and composition for the purpose of fog collection to survive the harsh conditions. With the unique ability of fog collection, these creatures could readily cope with insufficient access to fresh water or lack of precipitation. These natural examples have inspired the design and fabrication of artificial fog collection materials and devices. In this chapter, we will first introduce some natural examples for their unique fog collection capability, and then give some examples of the bioinspired materials and devices that are fabricated artificially to mimic these natural creatures for the purpose of fog collection. We believe that the biomimetic strategy is one of the most promising routes for the design and fabrication of functional materials and devices for the solution of the global water crisis.

  12. California spotted owls: Chapter 5 in Managing Sierra Nevada forests (United States)

    Roberts, Suzanne C.; Brooks, Matthew L.


    California spotted owls (Strix occidentalis occidentalis) are habitat specialists that are strongly associated with late-successional forests. For nesting and roosting, they require large trees and snags embedded in a stand with a complex forest structure (Blakesley et al. 2005, Gutiérrez et al. 1992, Verner et al. 1992b). In mixedconifer forests of the Sierra Nevada, California spotted owls typically nest and roost in stands with high canopy closure (≥75 percent) [Note: when citing studies, we use terminology consistent with Jennings et al. (1999), however, not all studies properly distinguish between canopy cover and closure and often use the terms interchangeably (see chapter 14 for clarification)] and an abundance of large trees (>24 in (60 cm) diameter at breast height [d.b.h.]) (Bias and Gutiérrez 1992, Gutiérrez et al. 1992, LaHaye et al. 1997, Moen and Gutiérrez 1997, Verner et al. 1992a). The California spotted owl guidelines (Verner et al. 1992b) effectively summarized much of the information about nesting and roosting habitat. Since that report, research on the California spotted owl has continued with much of the new information concentrated in five areas: population trends, barred owl (Strix varia) invasion, climate effects, foraging habitat, and owl response to fire.

  13. Chapter 9: Cryogenics for the HL-LHC

    CERN Document Server

    Claudet, S.


    Chapter 9 in High-Luminosity Large Hadron Collider (HL-LHC) : Preliminary Design Report. The Large Hadron Collider (LHC) is one of the largest scientific instruments ever built. Since opening up a new energy frontier for exploration in 2010, it has gathered a global user community of about 7,000 scientists working in fundamental particle physics and the physics of hadronic matter at extreme temperature and density. To sustain and extend its discovery potential, the LHC will need a major upgrade in the 2020s. This will increase its luminosity (rate of collisions) by a factor of five beyond the original design value and the integrated luminosity (total collisions created) by a factor ten. The LHC is already a highly complex and exquisitely optimised machine so this upgrade must be carefully conceived and will require about ten years to implement. The new configuration, known as High Luminosity LHC (HL-LHC), will rely on a number of key innovations that push accelerator technology beyond its present limits. Amon...


    Directory of Open Access Journals (Sweden)

    Luis Vaz


    Full Text Available The aim of the current study was to identify the Rugby game- related statistics that discriminated between winning and losing teams in IRB and S12 close games. Archival data reported to game-related statistics from 120 IRB games and 204 Super Twelve games played between 2003 and 2006. Afterwards, a cluster analysis was conducted to establish, according to game final score differences, three different match groups. Only the close games group was selected for further analysis (IRB n = 64 under 15 points difference and Super Twelve n = 95 under 11 points difference. An analysis to the structure coefficients (SC obtained through a discriminant analysis allowed to identify the most powerful game-related statistics in discriminating between winning and losing teams. The discriminant functions were statistically significant for Super Twelve games (Chi-square = 33.8, p < 0.01, but not for IRB games (Chi- square = 9.4, p = n.s.. In the first case, winners and losers were discriminated by possessions kicked (SC = 0.48, tackles made (SC = 0.45, rucks and pass (SC = -0.40, passes completed (SC = 0. 39, mauls won (SC = -0.36, turnovers won (SC = -0.33, kicks to touch (SC = 0.32 and errors made (SC = -0.32. The minus sign denotes higher values in losing teams. Rugby game-related statistics were able to discriminate between winners and losers in Super Twelve close games and suggest that a kicking based game supported by an effective defensive structure is more likely to win matches than a possession based one

  15. Edited Volumes, Monographs, and Book Chapters in the Book Citation Index (BCI) and Science Citation Index (SCI, SoSCI, A&HCI)

    CERN Document Server

    Leydesdorff, Loet


    In 2011, Thomson-Reuters introduced the Book Citation Index (BCI) as part of the Science Citation Index (SCI). The interface of the Web of Science version 5 enables users to search for both "Books" and "Book Chapters" as new categories. Books and book chapters, however, were always among the cited references, and book chapters have been included in the database since 2005. We explore the two categories with both BCI and SCI, and in the sister databases for the social sciences (SoSCI) and the arts and humanities (A&HCI). Book chapters in edited volumes can be highly cited. Books contain many citing references, but are relatively less cited. We suggest that this may find its origin in the slower circulation of books then of journal articles. It is possible to distinguish scientometrically between monographs and edited volumes among the "Books". Monographs may be underrated in terms of citation impact or overrated using publication performance indicators because individual chapters are counted separately as ...

  16. Edited volumes, monographs and book chapters in the Book Citation Index (BKCI and Science Citation Index (SCI, SoSCI, A&HCI

    Directory of Open Access Journals (Sweden)

    Loet Leydesdorff


    Full Text Available In 2011, Thomson-Reuters introduced the Book Citation Index (BKCI as part of the Science Citation Index (SCI. The interface of the Web of Science version 5 enables users to search for both ′Books′ and ′Book Chapters′ as new categories. Books and book chapters, however, were always among the cited references, and book chapters have been included in the database since 2005. We explore the two categories with both BKCI and SCI, and in the sister social sciences (SoSCI and the arts & humanities (A&HCI databases. Book chapters in edited volumes can be highly cited. Books contain many citing references but are relatively less cited. This may find its origin in the slower circulation of books than of journal articles. It is possible to distinguish between monographs and edited volumes among the ′Books′ scientometrically. Monographs may be underrated in terms of citation impact or overrated using publication performance indicators because individual chapters are counted as contributions separately in terms of articles, reviews, and/or book chapters.

  17. Radicular anatomy of twelve representatives of the Catasetinae subtribe (Orchidaceae: Cymbidieae

    Directory of Open Access Journals (Sweden)

    Cristiano Pedroso-de-Moraes


    Full Text Available Considering that the root structure of the Brazilian genera belonging to the Catasetinae subtribe is poorly known, we describe the roots of twelve representatives from this subtribe. For anatomical analysis, the roots were fixed in FAA 50, preserved in ethanol 70% and sectioned at its medium region using razor blades. The sections were stained with 0.05% astra blue and safranin and mounted in glycerin. For the identification of starch we used Lugol's solution; for lignin, floroglucin chloridric; for lipids, Sudan III, and for flavanoids, potassium hydroxide. The relevant aspects were registered using a digital camera joined with an Olympus microspope (BX51 model. The structural similarities of all roots support the placement of the subtribe Catasetinae into the monophyletic tribe Cymbidieae. Some root features are restricted to one or two taxa and can be useful in the systematics of the subtribe. For example, the occurrence of flavonoidic crystals characterizes the genera Catasetum and Cychnodes, and the number of the velamen layers and the shape of the epivelamen cells are useful to confirm the taxonomic position of Clowesia amazonica. The presence of velamen and flavonoidic crystals was interpreted as an adaptation to the epiphytic habit.Considerando que a estrutura das raízes de gêneros brasileiros pertencentes à subtribo Catasetinae é pouco conhecida, descrevemos as raízes de doze representantes desta subtribo. Para análise anatômica, as raízes foram fixadas em FAA 50, preservadas em álcool 70% e seccionadas na sua região média usando lâminas de barbear. Os cortes foram corados com astra blue e Safrablau 0,05% e montados em glicerina. Para a identificação do amido, utilizou-se a solução de Lugol; da lignina, floroglucina clorídrica, dos lipídios, Sudan III e dos flavonóides, hidróxido de potássio. Os aspectos relevantes foram registrados usando câmera digital acoplada a um microscópio Olympus (modelo BX51. As semelhan

  18. Some Meaningful Mathematics in Two Chapters: Chapter T1, The Binomial Expansion and Related Topics; Chapter T2, The Principle of Math Induction and Related Conjectures. (United States)

    Titterton, J. Patrick

    The author presents material suitable for use by teachers of gifted students in the junior or senior year of high school. The mathematics presented includes mathematical induction, the binomial expansion, number theory and Pascal's triangle. The author weaves much of the history of mathematics into the materials. Included are student tests and…

  19. Chapter A. The Loma Prieta, California, Earthquake of October 17, 1989 - Strong Ground Motion (United States)

    Borcherdt, Roger D.


    Strong ground motion generated by the Loma Prieta, Calif., earthquake (MS~7.1) of October 17, 1989, resulted in at least 63 deaths, more than 3,757 injuries, and damage estimated to exceed $5.9 billion. Strong ground motion severely damaged critical lifelines (freeway overpasses, bridges, and pipelines), caused severe damage to poorly constructed buildings, and induced a significant number of ground failures associated with liquefaction and landsliding. It also caused a significant proportion of the damage and loss of life at distances as far as 100 km from the epicenter. Consequently, understanding the characteristics of the strong ground motion associated with the earthquake is fundamental to understanding the earthquake's devastating impact on society. The papers assembled in this chapter address this problem. Damage to vulnerable structures from the earthquake varied substantially with the distance from the causative fault and the type of underlying geologic deposits. Most of the damage and loss of life occurred in areas underlain by 'soft soil'. Quantifying these effects is important for understanding the tragic concentrations of damage in such areas as Santa Cruz and the Marina and Embarcadero Districts of San Francisco, and the failures of the San Francisco-Oakland Bay Bridge and the Interstate Highway 880 overpass. Most importantly, understanding these effects is a necessary prerequisite for improving mitigation measures for larger earthquakes likely to occur much closer to densely urbanized areas in the San Francisco Bay region. The earthquake generated an especially important data set for understanding variations in the severity of strong ground motion. Instrumental strong-motion recordings were obtained at 131 sites located from about 6 to 175 km from the rupture zone. This set of recordings, the largest yet collected for an event of this size, was obtained from sites on various geologic deposits, including a unique set on 'soft soil' deposits

  20. Final Report for Dynamic Models for Causal Analysis of Panel Data. Approaches to the Censoring Problem in Analysis of Event Histories. Part III, Chapter 2. (United States)

    Tuma, Nancy Brandon; Hannan, Michael T.

    The document, part of a series of chapters described in SO 011 759, considers the problem of censoring in the analysis of event-histories (data on dated events, including dates of change from one qualitative state to another). Censoring refers to the lack of information on events that occur before or after the period for which data are available.…

  1. Omega Psi Phi Fraternity, Pi Chapter: African American Male Identity and Fraternity Culture, 1923-2003 (United States)

    Johnson, Edwin T.


    Pi Chapter of the Omega Psi Phi Fraternity, Inc. at Morgan State University made a significant contribution to the identity construction of college-educated African American men in the state of Maryland. The initiates of Pi Chapter constructed identities that allowed the members to see themselves as participants in mainstream American society as…

  2. Chapter 10. Developing a habitat monitoring program: three examples from national forest planning (United States)

    Michael I. Goldstein; Lowell H. Suring; Christina D. Vojta; Mary M. Rowland; Clinton. McCarthy


    This chapter reviews the process steps of wildlife habitat monitoring described in chapters 2 through 9 and provides three case examples that illustrate how the process steps apply to specific situations. It provides the reader an opportunity to synthesize the material while also revealing the potential knowledge gaps and pitfalls that may complicate completion of a...

  3. 38 CFR 21.380 - Establishment of qualifications for personnel providing assistance under Chapter 31. (United States)


    ... qualifications for personnel providing assistance under Chapter 31. 21.380 Section 21.380 Pensions, Bonuses, and....380 Establishment of qualifications for personnel providing assistance under Chapter 31. (a) General... consider qualification standards established for comparable personnel under the Rehabilitation Act of...

  4. Telemetry Standards, RCC Standard 106-17. Chapter 8. Digital Data Bus Acquisition Formatting Standard (United States)


    scope of this chapter. This chapter presents the general requirements for data formatting followed by individual sections addressing specifics...tape recording track (to extend record time), separate PCM streams shall be created and delayed by 24/TK bits with respect to each other, where TK

  5. A Summary of State Chapter 1 Participation and Achievement Information--1989-90. (United States)

    Sinclair, Beth; Gutmann, Babette

    This report summarizes the 1989-90 State Performance Reports for the Chapter 1 Basic Grants to Local Educational Agencies (LEAs) and the Chapter 1 State Agency Neglected or Delinquent Program. The Neglected or Delinquent Program served youths in state-operated adult and juvenile correctional facilities and facilities for neglected children. The…

  6. Classical mechanics including an introduction to the theory of elasticity

    CERN Document Server

    Hentschke, Reinhard


    This textbook teaches classical mechanics as one of the foundations of physics. It describes the mechanical stability and motion in physical systems ranging from the molecular to the galactic scale. Aside from the standard topics of mechanics in the physics curriculum, this book includes an introduction to the theory of elasticity and its use in selected modern engineering applications, e.g. dynamic mechanical analysis of viscoelastic materials. The text also covers many aspects of numerical mechanics, ranging from the solution of ordinary differential equations, including molecular dynamics simulation of many particle systems, to the finite element method. Attendant Mathematica programs or parts thereof are provided in conjunction with selected examples. Numerous links allow the reader to connect to related subjects and research topics. Among others this includes statistical mechanics (separate chapter), quantum mechanics, space flight, galactic dynamics, friction, and vibration spectroscopy. An introductory...

  7. Two Chapters of Technical Report: Unmanned Military Vehicles - Human Factors of Augmenting the Force Chapter 1: Introduction Chapter 8: Summary: Issues and Conclusions (United States)


    display technologies are also considered. Visual displays include: head- mounted and large wall-mounted, augmented/mixed reality, 3d stereoscopic and...credible. Using rapid prototyping tools that provide standard widgets, display templates, and auto -code generation allows the user interface designer

  8. Guidelines for Professional Referral to Alcoholics Anonymous and Other Twelve Step Groups. (United States)

    Riordan, Richard J.; Walsh, Lani


    Reviews 12-step programs, focusing on Alcoholics Anonymous (AA), the oldest and largest 12-step group. Explores criticisms of AA, describes its components and mechanics, and provides guidelines for client referral. Includes 28 citations. (Author/CRR)

  9. Student chapters: effective dissemination networks for informal optics and photonics education (United States)

    Fabian, Dirk; Vermeulen, Nathalie; Van Overmeire, Sara


    Professional societies sponsor student chapters in order to foster scholarship and training in photonics at the college and graduate level, but they are also an excellent resource for disseminating photonics knowledge to pre-college students and teachers. Starting in 2006, we tracked the involvement of SPIE student chapter volunteers in informal pre-college education settings. Chapter students reached 2800, 4900 and 11800 pre-college students respectively from 2006-2008 with some form of informal instruction in optics and photonics. As a case study, the EduKit, a self-contained instruction module featuring refractive and diffractive micro-optics developed by the European Network of Excellence on Micro-Optics (NEMO), was disseminated through student chapters in Argentina, Belgium, Canada, China, Colombia, India, Latvia, Mexico, Peru, Russia, Singapore, South Africa, and the United States. We tracked the movement of this material through the network, up to the student-teacher feedback stage. The student chapter network provided rapid dissemination of the material, translation of the material into the local language, and leveraged existing chapter contacts in schools to provide an audience. We describe the student chapter network and its impact on the development of the EduKit teaching module.

  10. Twelve invasive plant taxa in U.S. western riparian ecosystems (United States)

    Assessments of stream ecosystems often include an evaluation of riparian condition; a key stressor in riparian ecosystems is the presence of invasive plants. We analyzed the distribution of 12 invasive taxa (common burdock [Arctium minus], giant reed [Arundo donax], cheatgrass [B...

  11. Twelve Activities for Teaching the Pragmatics of Complaining to L2 Learners (United States)

    Hilliard, Amanda


    Pragmatic competence, or the ability to use language appropriately in a variety of contexts, is a critical skill for communication in a second language (L2). Thus, teaching that focuses on developing students' abilities to communicate effectively in an L2 must also include a focus on developing students' pragmatic competence. This article…

  12. Twelve Commandments of Human Relations for the Diverse Academic Environment of Colleges and Universities (United States)

    Davis, William Young; Swartz, Caroline


    This paper focuses on applying proven industrial relations approaches and sound management practice to address a range of diversity issues in higher education. Issues addressed include the need to set a clear and consistent direction, the importance of effective policy setting and enforcement, the value of positive reinforcement, and the…

  13. Theory including future not excluded

    DEFF Research Database (Denmark)

    Nagao, K.; Nielsen, H.B.


    We study a complex action theory (CAT) whose path runs over not only past but also future. We show that, if we regard a matrix element defined in terms of the future state at time T and the past state at time TA as an expectation value in the CAT, then we are allowed to have the Heisenberg equation......, Ehrenfest's theorem, and the conserved probability current density. In addition,we showthat the expectation value at the present time t of a future-included theory for large T - t and large t - T corresponds to that of a future-not-included theory with a proper inner product for large t - T. Hence, the CAT...

  14. Site characterization plan: Yucca Mountain Site, Nevada Research and Development Area, Nevada: Volume 8, Part B: Chapter 8, Sections 8.4 through 8.7; Glossary and Acronyms

    Energy Technology Data Exchange (ETDEWEB)



    This site characterization plan (SCP) has been developed for the candidate repository site at Yucca Mountain in the State of Nevada. The SCP includes a description of the Yucca Mountain site (Chapters 1-5), a conceptual design for the repository (Chapter 6), a description of the packaging to be used for the waste to be emplaced in the repository (Chapter 7), and a description of the planned site characterization activities (Chapter 8). The schedules and milestones presented in Section 8.3 and 8.5 of the SCP were developed to be consistent with the June 1988 draft Amendment to the DOE`s Mission Plan for the Civilian Radioactive Waste Management Program. The five month delay in the scheduled start of exploratory shaft construction that was announced recently is not reflected in these schedules. 88 figs., 42 tabs.

  15. Site characterization plan: Yucca Mountain Site, Nevada Research and Development Area, Nevada: Volume 8, Part B: Chapter 8, Sections 8.3.5 through

    Energy Technology Data Exchange (ETDEWEB)



    This site characterization plan (SCP) has been developed for the candidate repository site at Yucca Mountain in the State of Nevada. The SCP includes a description of the Yucca Mountain site (Chapters 1-5), a conceptual design for the repository (Chapter 6), a description of the packaging to be used for the waste to be emplaced in the repository (Chapter 7), and a description of the planned site characterization activities (Chapter 8). The schedules and milestones presented in Sections 8.3 and 8.5 of the SCP were developed to be consistent with the June 1988 draft Amendment to the DOE`s Mission Plan for the Civilian Radioactive Waste Management Program. The five month delay in the scheduled start of exploratory shaft construction that was announced recently is not reflected in these schedules. 68 figs., 102 tabs.

  16. Site characterization plan: Yucca Mountain Site, Nevada Research and Development Area, Nevada: Volume 5, Part B: Chapter 8, Sections through

    Energy Technology Data Exchange (ETDEWEB)



    This site characterization plan (SCP) has been developed for the candidate repository site at Yucca Mountain in the State of Nevada. The SCP includes a description of the Yucca Mountain site (Chapters 1-5), a conceptual design for the repository (Chapter 6), a description of the packaging to be used for the waste to be emplaced in the repository (Chapter 7), and a description of the planned site characterization activities (Chapter 8). The schedules and milestones presented in Sections 8.3 and 8.5 of the SCP were developed to be consistent with the June 1988 draft Amendment to the SOE`s Mission Plan for the Civilian Radioactive Waste Management Program. The five month delay in the scheduled start of exploratory shaft construction that was announced recently is not reflected in these schedules.

  17. The Effect o f Twelve - Week Recreation Act i v ities on the Anxiety Level of Female Pri soners

    Directory of Open Access Journals (Sweden)

    Zekiye B AŞARAN


    Full Text Available T h e a i m o f t h e s t u d y w a s to examine the effect of twelve - weeks recreation activities on the trait anxiety level of female prisoners in the prisons. The sampling of this study consists of 45 female prisoners who are in the Open Prison in Kandira, 22 of whom are in the experimental group and 23 of whom are in the control group. Different activities, such as music, dance, meditatio n, sportive activities, movies and videos, fun and entertainment activities and competitions, were performed one and half hours a day and two days a week. This lasted for twelve weeks. The data were collected by pre - tests and post - tests that were given bo th at the beginning and at the end of this program. Personal information form and Spielberger anxiety inventory were used as the data collecting tool. The reliability coefficient (Cronbach Alpha was calculated as ,873. The data were analysed with SPSS Win dows 18 programme. Descriptive statistics and Wilcoxon test were conducted. A si gnificant statistical correlation was determined between the prisoners’ pre - tests and post - tests scores in the experimental group (p <0.05. A s c o n c l u s i o n , a positive impact on trait anxiety levels of prisoners w a s f o u n d a f t e r 12 weeks o f recreational activities.

  18. Risk assessment of K basin twelve-inch drain valve failure from a postulated seismic initiating event

    Energy Technology Data Exchange (ETDEWEB)

    MORGAN, R.G.


    The Spent Nuclear Fuel (SNF) Project will transfer metallic SNF from the Hanford 105 K-East and 105 K-West Basins to safe interim storage in the Canister Storage Building in the 200 Area. The initial basis for design, fabrication, installation, and operation of the fuel removal systems was that the basin leak rates which could result from a postulated accident condition would not be excessive relative to reasonable recovery operations. However, an additional potential K Basin water leak path is through the K Basin drain valves. Three twelve-inch drain valves are located in the main basin bays along the north wall. The sumps containing the valves are filled with concrete which covers the drain valve body. Visual observations suggest that only the valve's bonnet and stem are exposed above the basin concrete floor. It was recognized, however, that damage of the drain valve bonnet or stem during a seismic initiating event could provide a potential K Basin water leak path. The objectives of this activity are to: (1) evaluate the risk of damaging the three twelve-inch drain valves located along the north wall of the main basin from a seismic initiating event, and (2) determine the associated potential leak rate from a damaged valve.

  19. Risk assessment of K basin twelve-inch drain valve failure from a postulated seismic initiating event

    Energy Technology Data Exchange (ETDEWEB)

    MORGAN, R.G.


    The Spent Nuclear Fuel (SNF) Project will transfer metallic SNF from the Hanford 105 K-East and 105 K-West Basins to safe interim storage in the Canister Storage Building in the 200 Area. The initial basis for design, fabrication, installation, and operation of the fuel removal systems was that the basin leak rates which could result from a postulated accident condition would not be excessive relative to reasonable recovery operations. However, an additional potential K Basin water leak path is through the K Basin drain valves. Three twelve-inch drain valves are located in the main basin bays along the north wall. The sumps containing the valves are filled with concrete which covers the drain valve body. Visual observations suggest that only the valve's bonnet and stem are exposed above the basin concrete floor. It was recognized, however, that damage of the drain valve bonnet or stem during a seismic initiating event could provide a potential K Basin water leak path. The objectives of this activity are to: (1) evaluate the risk of damaging the three twelve-inch drain valves located along the north wall of the main basin from a seismic initiating event, and (2) determine the associated potential leak rate from a damaged valve.

  20. Twelve tips to support the development of clinical reasoning skills using virtual patient cases. (United States)

    Posel, Nancy; Mcgee, James B; Fleiszer, David M


    Clinical reasoning is a critical core competency in medical education. Strategies to support the development of clinical reasoning skills have focused on methodologies used in traditional settings, including lectures, small groups, activities within Simulation Centers and the clinical arena. However, the evolving role and growing utilization of virtual patients (VPs) in undergraduate medical education; as well as an increased emphasis on blended learning, multi-modal models that include VPs in core curricula; suggest a growing requirement for strategies or guidelines that directly focus on VPs. The authors have developed 12 practical tips that can be used in VP cases to support the development of clinical reasoning. These are based on teaching strategies and principles of instructional design and pedagogy, already used to teach and assess clinical reasoning in other settings. Their application within VPs will support educators who author or use VP cases that promote the development of clinical reasoning.

  1. Twelve tips for teaching in a provincially distributed medical education program. (United States)

    Wong, Roger Y; Chen, Luke; Dhadwal, Gurbir; Fok, Mark C; Harder, Ken; Huynh, Hanh; Lunge, Ryan; Mackenzie, Mark; Mckinney, James; Ovalle, William; Rauniyar, Pooja; Tse, Luke; Villanyi, Diane


    As distributed undergraduate and postgraduate medical education becomes more common, the challenges with the teaching and learning process also increase. To collaboratively engage front line teachers in improving teaching in a distributed medical program. We recently conducted a contest on teaching tips in a provincially distributed medical education program and received entries from faculty and resident teachers. Tips that are helpful for teaching around clinical cases at distributed teaching sites include: ask "what if" questions to maximize clinical teaching opportunities, try the 5-min short snapper, multitask to allow direct observation, create dedicated time for feedback, there are really no stupid questions, and work with heterogeneous group of learners. Tips that are helpful for multi-site classroom teaching include: promote teacher-learner connectivity, optimize the long distance working relationship, use the reality television show model to maximize retention and captivate learners, include less teaching content if possible, tell learners what you are teaching and make it relevant and turn on the technology tap to fill the knowledge gap. Overall, the above-mentioned tips offered by front line teachers can be helpful in distributed medical education.

  2. Stress, burnout and doctors' attitudes to work are determined by personality and learning style: a twelve year longitudinal study of UK medical graduates. (United States)

    McManus, I C; Keeling, A; Paice, E


    The study investigated the extent to which approaches to work, workplace climate, stress, burnout and satisfaction with medicine as a career in doctors aged about thirty are predicted by measures of learning style and personality measured five to twelve years earlier when the doctors were applicants to medical school or were medical students. Prospective study of a large cohort of doctors. The participants were first studied when they applied to any of five UK medical schools in 1990. Postal questionnaires were sent to all doctors with a traceable address on the current or a previous Medical Register. The current questionnaire included measures of Approaches to Work, Workplace Climate, stress (General Health Questionnaire), burnout (Maslach Burnout Inventory), and satisfaction with medicine as a career and personality (Big Five). Previous questionnaires had included measures of learning style (Study Process Questionnaire) and personality. Doctors' approaches to work were predicted by study habits and learning styles, both at application to medical school and in the final year. How doctors perceive their workplace climate and workload is predicted both by approaches to work and by measures of stress, burnout and satisfaction with medicine. These characteristics are partially predicted by trait measures of personality taken five years earlier. Stress, burnout and satisfaction also correlate with trait measures of personality taken five years earlier. Differences in approach to work and perceived workplace climate seem mainly to reflect stable, long-term individual differences in doctors themselves, reflected in measures of personality and learning style.

  3. A class III archaeological survey of twelve region wide fencing upgrade locations in Eagle, Grand, Gunnison, Jackson, Moffat, Pitkin, and Routt counties, Colorado (United States)

    US Fish and Wildlife Service, Department of the Interior — The Colorado Department of Transportation proposes to upgrade existing right-of-way fencing along roadways at twelve separate locations in northwestern Colorado. To...

  4. Biodiversity conservation including uncharismatic species

    DEFF Research Database (Denmark)

    Muñoz, Joaquin


    Recent papers mention ideas on the topics of biodiversity conservation strategies and priorities (Redford et al. 2003; Lamoreux et al. 2006; Rodrı´guez et al. 2006), the current status of biodiversity (Loreau et al. 2006), the obligations of conservation biologists regarding management policies...... (Chapron 2006; Schwartz 2006), and the main threats to biodiversity (including invasive species) (Bawa 2006). I suggest, however, that these articles do not really deal with biodiversity. Rather, they all focus on a few obviously charismatic groups (mammals, birds, some plants, fishes, human culture...

  5. FLUXNET2015 Dataset: Batteries included (United States)

    Pastorello, G.; Papale, D.; Agarwal, D.; Trotta, C.; Chu, H.; Canfora, E.; Torn, M. S.; Baldocchi, D. D.


    The synthesis datasets have become one of the signature products of the FLUXNET global network. They are composed from contributions of individual site teams to regional networks, being then compiled into uniform data products - now used in a wide variety of research efforts: from plant-scale microbiology to global-scale climate change. The FLUXNET Marconi Dataset in 2000 was the first in the series, followed by the FLUXNET LaThuile Dataset in 2007, with significant additions of data products and coverage, solidifying the adoption of the datasets as a research tool. The FLUXNET2015 Dataset counts with another round of substantial improvements, including extended quality control processes and checks, use of downscaled reanalysis data for filling long gaps in micrometeorological variables, multiple methods for USTAR threshold estimation and flux partitioning, and uncertainty estimates - all of which accompanied by auxiliary flags. This "batteries included" approach provides a lot of information for someone who wants to explore the data (and the processing methods) in detail. This inevitably leads to a large number of data variables. Although dealing with all these variables might seem overwhelming at first, especially to someone looking at eddy covariance data for the first time, there is method to our madness. In this work we describe the data products and variables that are part of the FLUXNET2015 Dataset, and the rationale behind the organization of the dataset, covering the simplified version (labeled SUBSET), the complete version (labeled FULLSET), and the auxiliary products in the dataset.

  6. Twelve months follow-up after retrograde recanalization of superficial femoral artery chronic total occlusion

    Directory of Open Access Journals (Sweden)

    Joanna Wojtasik-Bakalarz


    Full Text Available Introduction : Fifty percent of cases of peripheral artery disease are caused by chronic total occlusion (CTO of the superficial femoral artery (SFA. Ten–fifteen percent of percutaneous SFA recanalization procedures are unsuccessful. In those cases the retrograde technique can increase the success rate of the procedure, but the long-term follow-up of such procedures is still unknown. Aim : To assess the efficacy and clinical outcomes during long-term follow-up after retrograde recanalization of the SFA. Material and methods: We included patients after at least one unsuccessful percutaneous antegrade recanalization of the SFA. Patients were evaluated for the procedural and clinical follow-up of mean time 13.9 months. Results: The study included 17 patients (7 females, 10 males who underwent percutaneous retrograde recanalization of the SFA from June 2011 to June 2015. The mean age of patients was 63 ±7 years. Retrograde puncture of the distal SFA was successful in all cases. A retrograde procedure was performed immediately after antegrade failure in 4 (23.5% patients and after a previously failed attempt in 13 (76.5% patients. The procedure was successful in 15 (88.2% patients, and unsuccessful in 2 (11.8% patients. Periprocedural complications included 1 peripheral distal embolization (successfully treated with aspiration thrombectomy, 1 bleeding event from the puncture site and 7 puncture site hematomas. During follow-up the all-cause mortality rate was 5.8% (1 patient, non-cardiac death. The primary patency rate at 12 months was 88.2% and secondary patency 100%. Conclusions : The retrograde SFA puncture seems to be a safe and successful technique for CTO recanalization and is associated with a low rate of perioperative and long-term follow-up complications.

  7. Twelve tips for getting started using mixed methods in medical education research. (United States)

    Lavelle, Ellen; Vuk, Jasna; Barber, Carolyn


    Mixed methods research, which is gaining popularity in medical education, provides a new and comprehensive approach for addressing teaching, learning, and evaluation issues in the field. The aim of this article is to provide medical education researchers with 12 tips, based on consideration of current literature in the health professions and in educational research, for conducting and disseminating mixed methods research. Engaging in mixed methods research requires consideration of several major components: the mixed methods paradigm, types of problems, mixed method designs, collaboration, and developing or extending theory. Mixed methods is an ideal tool for addressing a full range of problems in medical education to include development of theory and improving practice.

  8. Algorithms and their Impact on Integrated Vehicle Health Management - Chapter 7 (United States)

    National Aeronautics and Space Administration — This chapter discussed some of the algorithmic choices one encounters when designing an IVHM system. While it would be generally desirable to be able to pick a...

  9. 22 CFR Appendix A to Chapter Xiv - Current Addresses and Geographic Jurisdictions (United States)


    ... DISPUTES PANEL Ch. XIV, App. A Appendix A to Chapter XIV—Current Addresses and Geographic Jurisdictions (a... Boston New Jersey New York New Mexico Dallas New York Boston/New York 2 North Carolina Atlanta North...

  10. Mapping Citation Patterns of Book Chapters in the Book Citation Index

    CERN Document Server

    Torres-Salinas, Daniel; Robinson-Garcia, Nicolas; Fdez-Valdivia, J; García, J A; 10.1016/j.joi.2013.01.004


    In this paper we provide the reader with a visual representation of relationships among the impact of book chapters indexed in the Book Citation Index using information gain values and published by different academic publishers in specific disciplines. The impact of book chapters can be characterized statistically by citations histograms. For instance, we can compute the probability of occurrence of book chapters with a number of citations in different intervals for each academic publisher. We predict the similarity between two citation histograms based on the amount of relative information between such characterizations. We observe that the citation patterns of book chapters follow a Lotkaian distribution. This paper describes the structure of the Book Citation Index using 'heliocentric clockwise maps' which allow the reader not only to determine the grade of similarity of a given academic publisher indexed in the Book Citation Index with a specific discipline according to their citation distribution, but al...

  11. Master plan study - District heating Sillamaee municipality. Estonia. Final report. Appendices for chapter 9

    Energy Technology Data Exchange (ETDEWEB)



    The appendices to the final report on the master plan study on district heating in the municipality in Estonia, chapter nine, gives data related to general economic assumptions for financial and economic calculations, fuel consumption, financing, prices, fuel consumption. (ARW)

  12. Compensatory Education: Chapter 1's Comparability of Services Provision. United States General Accounting Office Report to the Secretary of Education. (United States)

    General Accounting Office, Washington, DC. Div. of Human Resources.

    Chapter 1 was created from its predecessor, Title 1, in order to give more flexibility to states and local school districts. Many of the requirements and criteria of Title 1 were relaxed in 1981 when Chapter 1 began. Districts are now required to submit written plans of their new Chapter 1 organization assuring the comparability of services…

  13. The Extension of The Twelve-Point Sphere Theorem for a Tetrahedron%四面体的十二点二次曲面

    Institute of Scientific and Technical Information of China (English)

    王奇志; 王东生


    垂心四面体中四条高的垂足,四个面的重心及从各顶点与四面体的垂心连线的三等分点,共十二个点共球.试图把垂心改为四面体内的任意点,相应地把四条高线改换为过该点与每个顶点连线的共点直线组时,则将把垂心四面体的十二点球有趣地推广为四面体的十二点二次曲面.%The four feet of four altitudes for an orthocenter tetrahedron, the centers of gravity of the four faces, the trisection of the line segments from the orthocenter to four summits, total twelve points lie on same sphere, which is known as twelve-point sphere. If the orthocenter can be changed into any point within a tetrahedron in this paper, and corresponding the four perpendiculars also can be changed into the four lines segment passing through the given point to the summits of the tetrahedron, the twelve-point sphere can be changed into twelve-point quadric surface. Twelve point sphere of an orthocenter tetrahedron can be generalized to the twelve-point quadratic surface of a tetrahedron.

  14. Families classification including multiopposition asteroids (United States)

    Milani, Andrea; Spoto, Federica; Knežević, Zoran; Novaković, Bojan; Tsirvoulis, Georgios


    In this paper we present the results of our new classification of asteroid families, upgraded by using catalog with > 500,000 asteroids. We discuss the outcome of the most recent update of the family list and of their membership. We found enough evidence to perform 9 mergers of the previously independent families. By introducing an improved method of estimation of the expected family growth in the less populous regions (e.g. at high inclination) we were able to reliably decide on rejection of one tiny group as a probable statistical fluke. Thus we reduced our current list to 115 families. We also present newly determined ages for 6 families, including complex 135 and 221, improving also our understanding of the dynamical vs. collisional families relationship. We conclude with some recommendations for the future work and for the family name problem.

  15. Manhattan Project Technical Series The Chemistry of Uranium (I) Chapters 1-10

    Energy Technology Data Exchange (ETDEWEB)

    Rabinowitch, E. I. [Argonne National Laboratory (ANL), Argonne, IL (United States); Katz, J. J. [Argonne National Laboratory (ANL), Argonne, IL (United States)


    This constitutes Chapters 1 through 10. inclusive, of The Survey Volume on Uranium Chemistry prepared for the Manhattan Project Technical Series. Chapters are titled: Nuclear Properties of Uranium; Properties of the Uranium Atom; Uranium in Nature; Extraction of Uranium from Ores and Preparation of Uranium Metal; Physical Properties of Uranium Metal; Chemical Properties of Uranium Metal; Intermetallic Compounds and Alloy systems of Uranium; the Uranium-Hydrogen System; Uranium Borides, Carbides, and Silicides; Uranium Nitrides, Phosphides, Arsenides, and Antimonides.

  16. Teaching molecular genetics: Chapter 1--Background principles and methods of molecular biology. (United States)

    Knoers, Nine V A M; Monnens, Leo A H


    In this first chapter of the series "Teaching molecular genetics," an introduction to molecular genetics is presented. We describe the structure of DNA and genes and explain in detail the central dogma of molecular biology, that is, the flow of genetic information from DNA via RNA to polypeptide (protein). In addition, several basic and frequently used general molecular tools, such as restriction enzymes, Southern blotting, DNA amplification and sequencing are discussed, in order to lay the foundations for the forthcoming chapters.

  17. Impacts on integrated spatial and infrastructure planning (Chapter18)

    CSIR Research Space (South Africa)

    Van Huyssteen, Elsona


    Full Text Available fracturing (“fracking”)), however, require proper access, usually along unpaved access roads. During exploration movement (Paige- Green, 2015; 2016) activities include regular movement of staff, equipment, fuel and provisions and maintenance vehicles...

  18. Twelve tips for the construction of ethical dilemma case-based assessment. (United States)

    Tsai, Tsuen-Chiuan


    Ethical dilemma case-based examination (ethics Script Concordance Test, eSCT) is a written examination that can be delivered to a large group of examinees for the purpose of measuring high-level thinking. As it accommodates for diverse responses from experts, ethics SCT allows partial credits. The framework of ethics SCT includes a vignette with an ethical dilemma and a leading question, which asks the examinee to "agree" or "disagree", plus the shifts of prior decision by adding new information. In this article, the following tips for constructing this type of examination are provided: use "true" dilemmas, select an appropriate ethical issue, target high-level cognitive tasks, list key components, keep a single central theme, device quality scoring system, be important and plausible, be clear, select quality experts, validate, know the limitation, and be familiar with test materials. The use of eSCT to measure ethical reasoning ability appears to be both viable and desirable.

  19. Twelve tips for applying the science of learning to health professions education. (United States)

    Gooding, H C; Mann, K; Armstrong, E


    Findings from the science of learning have clear implications for those responsible for teaching and curricular design. However, this data has been historically siloed from educators in practice, including those in health professions education. In this article, we aim to bring practical tips from the science of learning to health professions educators. We have chosen to organize the tips into six themes, highlighting strategies for 1) improving the processing of information, 2) promoting effortful learning for greater retention of knowledge over time, 3) applying learned information to new and varied contexts, 4) promoting the development of expertise, 5) harnessing the power of emotion for learning, and 6) teaching and learning in social contexts. We conclude with the importance of attending to metacognition in our learners and ourselves. Health professions education can be strengthened by incorporating these evidence-based techniques.

  20. The OCCASO survey: Presentation and radial velocities of twelve Milky Way Open Clusters

    CERN Document Server

    Casamiquela, L; Jordi, C; Balaguer-Núñez, L; Pancino, E; Hidalgo, S L; Martínez-Vázquez, C E; Murabito, S; del Pino, A; Aparicio, A; Blanco-Cuaresma, S; Gallart, C


    Open clusters (OCs) are crucial for studying the formation and evolution of the Galactic disc. However, the lack of a large number of OCs analyzed homogeneously hampers the investigations about chemical patterns and the existence of Galactocentric radial and vertical gradients, or an age-metallicity relation. To overcome this, we have designed the Open Cluster Chemical Abundances from Spanish Observatories survey (OCCASO). We aim to provide homogeneous radial velocities, physical parameters and individual chemical abundances of six or more Red Clump stars for a sample of 25 old and intermediate-age OCs visible from the Northern hemisphere. To do so, we use high resolution spectroscopic facilities (R> 62,000) available at Spanish observatories. We present the motivation, design and current status of the survey, together with the first data release of radial velocities for 77 stars in 12 OCs, which represents about 50% of the survey. We include clusters never studied with high-resolution spectroscopy before (NG...

  1. Twelve thousand laser-AO observations: first results from the Robo-AO large surveys (United States)

    Law, Nicholas M.; Baranec, Christoph; Riddle, Reed L.


    Robo-AO is the first AO system which can feasibly perform surveys of thousands of targets. The system has been operating in a fully robotic mode on the Palomar 1.5m telescope for almost two years. Robo-AO has completed nearly 12,000 high-angular-resolution observations in almost 20 separate science programs including exoplanet characterization, field star binarity, young star binarity and solar system observations. We summarize the Robo-AO surveys and the observations completed to date. We also describe the data-reduction pipeline we developed for Robo-AO—the first fully-automated AO data-reduction, point-spread-function subtraction and companion-search pipeline.

  2. Predictors of the change in bilirubin levels over twelve weeks of treatment with atazanavir

    LENUS (Irish Health Repository)

    Cotter, Aoife G


    AbstractObjectiveTo determine the factors associated with change in bilirubin concentration 12 weeks after the initiation of an atazanavir (ATV)-containing antiretroviral regimen.MethodsWe performed a retrospective case note review of all patients prescribed ATV between January 2004 and October 2007 in a cohort of HIV infected subjects. Data collected included baseline demographics, hepatitis B and C serology, current antiretroviral therapy, baseline and week 12 routine bloods. The primary endpoint was the change in bilirubin concentration at 12 weeks after start of ATV. Multvariable linear regression was performed to assess the relationships between the change in bilirubin and variables of interest. Results: Eighty-three ATV-treated patients were included in the analysis of whom 46 (60.5%) were hepatitis C antibody positive. The median (interquartile range) change in bilirubin by week 12 was 16 (4, 22) umol\\/L; only 1 patient developed grade 4 hyperbilirubinaemia at week 12. After controlling for baseline bilirubin levels, HCV seropositivity and baseline ALP were associated with a smaller change in bilirubin over the 12 weeks with a trend towards lower increases in those receiving tenofovir. Sensitivity analyses reported similar associations with methadone use and injection drug use, when these variables replaced HCV sero-positivity in the model. Conclusion: Patients with hepatitis C co-infection experience smaller changes in bilirubin upon exposure to ATV. Although the underlying mechanism for this association remains unclear, these data support the safe use of this drug in this patient setting. Further research into the clinical predictors of ATV-related hyperbilirubinaemia is warranted.

  3. A move-step analysis of the concluding chapters in computer science PhD theses

    Directory of Open Access Journals (Sweden)

    Carmen Soler-Monreal


    Full Text Available This paper describes how computer science doctoral writers construct the closing chapters of their PhD theses. The data are drawn from the chapters playing a concluding role of 48 PhD theses defended at the University of Glasgow from 2008 to 2014. The analysis applied a qualitative-quantitative approach. The titles of the concluding chapters of the theses were first examined and also their divisions into sections and sub-sections. Then the chapters were subjected to a move-step analysis: Move 1 (M1 “Revisiting the study”; Move 2 (M2 “Consolidating research space”; Move 3 (M3 “Proposing practical applications and implications”, Move 4 (M4 “Recommending future work” and Move 5 (M5 “Recapitulating the study”. The results revealed that most of the computer science PhD theses have one final concluding chapter with three main moves: M1, M2 and M4. The most frequent steps are “reviewing the work carried out” and “summarizing the specific work reported in every thesis chapter” in M1, “presenting results and contributions”, “answering the initial research questions or hypotheses”, and “making claims” in M2, and “acknowledging limitations” and “suggesting further research” in M4. Movestep patterns appear in recurrent cycles throughout the concluding chapters. Several suggestions for pedagogical purposes are provided.

  4. Including Magnetostriction in Micromagnetic Models (United States)

    Conbhuí, Pádraig Ó.; Williams, Wyn; Fabian, Karl; Nagy, Lesleis


    The magnetic anomalies that identify crustal spreading are predominantly recorded by basalts formed at the mid-ocean ridges, whose magnetic signals are dominated by iron-titanium-oxides (Fe3-xTixO4), so called "titanomagnetites", of which the Fe2.4Ti0.6O4 (TM60) phase is the most common. With sufficient quantities of titanium present, these minerals exhibit strong magnetostriction. To date, models of these grains in the pseudo-single domain (PSD) range have failed to accurately account for this effect. In particular, a popular analytic treatment provided by Kittel (1949) for describing the magnetostrictive energy as an effective increase of the anisotropy constant can produce unphysical strains for non-uniform magnetizations. I will present a rigorous approach based on work by Brown (1966) and by Kroner (1958) for including magnetostriction in micromagnetic codes which is suitable for modelling hysteresis loops and finding remanent states in the PSD regime. Preliminary results suggest the more rigorously defined micromagnetic models exhibit higher coercivities and extended single domain ranges when compared to more simplistic approaches.

  5. Evaluation of Anomaly Detection Capability for Ground-Based Pre-Launch Shuttle Operations. Chapter 8 (United States)

    Martin, Rodney Alexander


    This chapter will provide a thorough end-to-end description of the process for evaluation of three different data-driven algorithms for anomaly detection to select the best candidate for deployment as part of a suite of IVHM (Integrated Vehicle Health Management) technologies. These algorithms were deemed to be sufficiently mature enough to be considered viable candidates for deployment in support of the maiden launch of Ares I-X, the successor to the Space Shuttle for NASA's Constellation program. Data-driven algorithms are just one of three different types being deployed. The other two types of algorithms being deployed include a "nile-based" expert system, and a "model-based" system. Within these two categories, the deployable candidates have already been selected based upon qualitative factors such as flight heritage. For the rule-based system, SHINE (Spacecraft High-speed Inference Engine) has been selected for deployment, which is a component of BEAM (Beacon-based Exception Analysis for Multimissions), a patented technology developed at NASA's JPL (Jet Propulsion Laboratory) and serves to aid in the management and identification of operational modes. For the "model-based" system, a commercially available package developed by QSI (Qualtech Systems, Inc.), TEAMS (Testability Engineering and Maintenance System) has been selected for deployment to aid in diagnosis. In the context of this particular deployment, distinctions among the use of the terms "data-driven," "rule-based," and "model-based," can be found in. Although there are three different categories of algorithms that have been selected for deployment, our main focus in this chapter will be on the evaluation of three candidates for data-driven anomaly detection. These algorithms will be evaluated upon their capability for robustly detecting incipient faults or failures in the ground-based phase of pre-launch space shuttle operations, rather than based oil heritage as performed in previous studies. Robust

  6. Introduction to Radiation Issues for International Space Station Extravehicular Activities. Chapter 1 (United States)

    Shavers, M. R.; Saganti, P. B.; Miller, J.; Cucinotta, F. A.


    The International Space Station (ISS) provides significant challenges for radiation protection of the crew due to a combination of circumstances including: the extended duration of missions for many crewmembers, the exceptionally dynamic nature of the radiation environment in ISS orbit, and the necessity for numerous planned extravehicular activities (EVA) for station construction and maintenance. Radiation protection requires accurate radiation dose measurements and precise risk modeling of the transmission of high fluxes of energetic electrons and protons through the relatively thin shielding provided by the space suits worn during EVA. Experiments and analyses have been performed due to the necessity to assure complete radiation safety for the EVA crew and thereby ensure mission success. The detailed characterization described of the material and topological properties of the ISS space suits can be used as a basis for design of space suits used in future exploration missions. In radiation protection practices, risk from exposure to ionizing radiation is determined analytically by the level of exposure, the detrimental quality of the radiation field, the inherent radiosensitivity of the tissues or organs irradiated, and the age and gender of the person at the time of exposure. During low Earth orbit (LEO) EVA, the relatively high fluxes of low-energy electrons and protons lead to large variations in exposure of the skin, lens of the eye, and tissues in other shallow anatomical locations. The technical papers in this publication describe a number of ground-based experiments that precisely measure the thickness of the NASA extravehicular mobility unit (EMU) and Russian Zvezda Orlan-M suits using medical computerized tomography (CT) X-ray analysis, and particle accelerator experiments that measure the minimum kinetic energy required by electrons and photons to penetrate major components of the suits. These studies provide information necessary for improving the

  7. Birth, growth and progresses through the last twelve years of a regional scale landslide warning system (United States)

    Fanti, Riccardo; Segoni, Samuele; Rosi, Ascanio; Lagomarsino, Daniela; Catani, Filippo


    recordings and landslides occurred) and to use them to define more robust relationships between rainfalls and landslide triggering, with the final aim to increase the forecasting effectiveness of the warning system. The updated rainfall and landslide database were used to periodically perform a quantitative validation and to analyze the errors affecting the system forecasts. The errors characterization was used to implement a continuous process of updating and modification of SIGMA, that included: - Main model upgrades (generalization from a pilot test site to the whole Emilia Romagna region; calibration against well documented landslide events to define specific σ levels for each territorial units; definition of different alert levels according to the number of expected - Ordinary updates (periodically, the new landslide and rainfall data were used to re-calibrate the thresholds, taking into account a more robust sample). - Model tuning (set up of the optimal version of the decisional algorithm, including different definitions of "long" and "short" periods; selection of the optimal reference rain gauge for each Territorial Unit; modification of the boundaries of some territorial - Additional features (definition of a module that takes into account the effect of snow melt and snow accumulation; coupling with a landslide susceptibility model to improve the spatial accuracy of the model). - Various performance tests (including the comparison with alternate versions of SIGMA or with thresholds based on rainfall intensity and duration). This process has led to an evolution of the warning system and to a documented improvement of its forecasting effectiveness. Landslide forecasting at regional scale is a very complex task, but as time passes by and with the systematic gathering of new substantial data and the continuous progresses of research, uncertainties can be progressively reduced and a warning system can be set that increases its performances and reliability with time.

  8. Total Water Vapor Transport Observed in Twelve Atmospheric Rivers over the Northeastern Pacific Ocean Using Dropsondes (United States)

    Ralph, F. M.; Iacobellis, S.; Neiman, P. J.; Cordeira, J. M.; Spackman, J. R.; Waliser, D. E.; Wick, G. A.; White, A. B.; Fairall, C. W.


    Demory et al (2013) recently showed that the global water cycle in climate models, including the magnitude of water vapor transport, is strongly influenced by the model's spatial resolution. The lack of offshore observations is noted as a serious limitation in determining the correct amount of transport. Due to the key role of atmospheric rivers (ARs) in determining the global distribution of water vapor, quantifying transport from ARs is a high priority. This forms a foundation of the CalWater-2 experiment aimed at sampling many ARs during 2014-2018. In February 2014, an "early-start" deployment of the NOAA G-IV research aircraft sampled 10 ARs over the northeast Pacific Ocean. On six of these flights, dropsondes were deployed in a line crossing the AR so as to robustly sample the total water vapor transport (TVT). The TVT is defined here as the sum of the vertically integrated horizontal water vapor transport (IVT) in the AR using a baseline that stretches from its warm southern (or eastern) edge to its cool northern (or western) edge. TVT includes both AR-parallel and AR-perpendicular transport. These data double the overall number of such cross-AR airborne samples suitable for calculating TVT. Analysis of TVT for these six new samples, in combination with the six previous samples from the preceding 16 years (from CalJet, WISPAR, and a Hawaii-based campaign), will be shown. A comparison will be made of the AR width and TVT determined using the well-established integrated water vapor (IWV) threshold of 2 cm, versus an IVT threshold of 250 kg m-1 s-1. Finally, the data from a well sampled case on 13 February 2014 (23 sondes with 75-100 km spacing) will be used to assess the sensitivity of TVT to dropsonde horizontal spacing and vertical resolution. This sensitivity analysis is of practical importance for the upcoming CalWater-2 field campaign where the G-IV will be used to sample many additional AR events, due to the relatively high cost of the dropsondes.

  9. Academic style and format of doctoral theses: The case of the disappearing discussion chapter

    Directory of Open Access Journals (Sweden)

    Elaine Hewitt


    Full Text Available This article describes work carried out within the sphere of analysis of university academic discourse that possibly contains an intercultural comparative element. A hypothesis was put forward that when Spanish doctoral students crafted their theses, they would pass over the Discussion chapter and progress directly on to the Conclusions. The propensity for Spanish doctoral students to miss out discussion of the results in their doctoral theses was noticed by the first author, while supervising her own doctoral students’ empirical Ph.D. theses in the field of English Studies in Spain. It was thought that this oversight may indicate intercultural variation in the preferences of format for different writing cultures. The initial corpus consisted of sixteen theses from the field of English Studies. At a second stage, an additional corpus of thirty-nine theses in the field of Spanish Studies was included. Both corpora had been defended in these two areas in Spanish universities over the last 10 years and were full-text theses from a Spanish national data base: Dialnet. The results confirmed the hypothesis in both corpora with students in Spanish universities. Nevertheless, curiously, a number of further intervening variables were also found to be essential. For the theses from the area of Spanish Studies less divergence was encountered but, on the other hand, evidence was found that may even point to a lingering influence of national or educational rhetoric.

  10. The science, information, and engineering needed to manage water availability and quality in 2050: Chapter 23 (United States)

    Hirsch, Robert M.


    This chapter explores four water resources issues: 1) hydrologic variability, hazards, water supply and ecosystem preservation; 2) urban landscape design; 3) non-point source water quality, and 4) climate change, resiliency, and nonstationarity. It also considers what science, technology, and engineering practice may be needed in the coming decades to sustain water supplies and ecosystems in the face of increasing stresses from a growing demand for water. Dealing with these four water resource issues in the highly uncertain future would will demand predictive models that are rooted in real-world data. In a non-stationary world, continuity of observations is crucial. All watersheds are influenced by human actions through changes in land use, water use, and climate. The focus of water planning and management between today and 2050 will depend more than ever on collection and analysis of long-term data to learn about the evolving state of the system, understanding ecosystem processes in the water and on the landscape, and finding innovative ways to manage water as a shared resource. This includes sharing water with our neighbors on the landscape, sharing with the other species that depend on water, and sharing with future generations.

  11. Chapter 5: Modulation Excitation Spectroscopy with Phase-Sensitive Detection for Surface Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Shulda, Sarah; Richards, Ryan M.


    Advancements in in situ spectroscopic techniques have led to significant progress being made in elucidating heterogeneous reaction mechanisms. The potential of these progressive methods is often limited only by the complexity of the system and noise in the data. Short-lived intermediates can be challenging, if not impossible, to identify with conventional spectra analysis means. Often equally difficult is separating signals that arise from active and inactive species. Modulation excitation spectroscopy combined with phase-sensitive detection analysis is a powerful tool for removing noise from the data while simultaneously revealing the underlying kinetics of the reaction. A stimulus is applied at a constant frequency to the reaction system, for example, a reactant cycled with an inert phase. Through mathematical manipulation of the data, any signal contributing to the overall spectra but not oscillating with the same frequency as the stimulus will be dampened or removed. With phase-sensitive detection, signals oscillating with the stimulus frequency but with various lag times are amplified providing valuable kinetic information. In this chapter, some examples are provided from the literature that have successfully used modulation excitation spectroscopy with phase-sensitive detection to uncover previously unobserved reaction intermediates and kinetics. Examples from a broad range of spectroscopic methods are included to provide perspective to the reader.

  12. Shrews, rats, and a polecat in "the pardoner’s tale": Chapter 3 (United States)

    Feinstein, Sandy; Woodman, Neal; Van Dyke, Carolynn


    While historically existing animals and literary animal characters inform allegorical and metaphorical characterization in The Canterbury Tales, figurative usage does not erase recognition of the material animal. "The Pardoner's Tale," for one, challenges the terms of conventional animal metaphors by refocusing attention on common animals as common animals and common human creatures as something worse than vermin. Most attention has been paid to the larger animals-goat, hare, and horse-that constitute the physical portrait of Chaucer's Pardoner in the "General Prologue" and in the prologue to his tale.! Like these animals, rats and a polecat, together with rhetorical shrews, appear in this tale as well as in other literature, including bestiaries and natural histories. Equally to the purpose, these animals could be physically observed as constituents of both urban and rural landscapes in fourteenth-century England.2 In the Middle Ages, animals were part of the environment as well as part of the culture: they lived inside as well as outside the city gates, priory walls, and even domestic spaces; a rat in the street or the garden might not be any less welcome or uncommon than encountering someone's horses and goats nibbling vegetation or blocking a passage. Not being out of the ordinary, though, such animals could (and can) be overlooked or dismissed as com­mon, too familiar to register. This chapter reveals why readers and listeners should pay close attention to the things they think they know and what they hear about what they think they know.

  13. A new chapter in pharmaceutical manufacturing: 3D-printed drug products. (United States)

    Norman, James; Madurawe, Rapti D; Moore, Christine M V; Khan, Mansoor A; Khairuzzaman, Akm


    FDA recently approved a 3D-printed drug product in August 2015, which is indicative of a new chapter for pharmaceutical manufacturing. This review article summarizes progress with 3D printed drug products and discusses process development for solid oral dosage forms. 3D printing is a layer-by-layer process capable of producing 3D drug products from digital designs. Traditional pharmaceutical processes, such as tablet compression, have been used for decades with established regulatory pathways. These processes are well understood, but antiquated in terms of process capability and manufacturing flexibility. 3D printing, as a platform technology, has competitive advantages for complex products, personalized products, and products made on-demand. These advantages create opportunities for improving the safety, efficacy, and accessibility of medicines. Although 3D printing differs from traditional manufacturing processes for solid oral dosage forms, risk-based process development is feasible. This review highlights how product and process understanding can facilitate the development of a control strategy for different 3D printing methods. Overall, the authors believe that the recent approval of a 3D printed drug product will stimulate continual innovation in pharmaceutical manufacturing technology. FDA encourages the development of advanced manufacturing technologies, including 3D-printing, using science- and risk-based approaches. Published by Elsevier B.V.

  14. Non-melanoma Skin Cancer in Canada Chapter 1: Introduction to the Guidelines. (United States)

    Guenther, Lyn C; Barber, Kirk; Searles, Gordon E; Lynde, Charles W; Janiszewski, Peter; Ashkenas, John


    Non-melanoma skin cancer (NMSC), including basal and squamous cell carcinoma, represents the most common malignancy. The aim of this document is to provide guidance to Canadian health care practitioners on NMSC management. After conducting a literature review, the group developed recommendations for prevention, management, and treatment of basal cell carcinomas, squamous cell carcinomas, and actinic keratoses. These tumour types are considered separately in the accompanying articles. The Grading of Recommendations Assessment, Development and Evaluation system was used to assign strength to each recommendation. This introduction describes the scope and structure of the guidelines and the methods used to develop them. The epidemiology of NMSC is reviewed, as are the pathophysiologic changes occurring with damage to the skin, which lead to the formation of actinic keratoses and invasive squamous or basal cell carcinomas. This introduction describes the need for primary prevention and offers an overview of treatment options that are discussed in later chapters of the guidelines. © The Author(s) 2015.

  15. Review of Pasteurella Multocida Infections over a Twelve-Year Period in a Tertiary Care Hospital

    Directory of Open Access Journals (Sweden)

    Athanasia Christidou


    Full Text Available The aim of this study was to present the epidemiological, clinical and microbiological data, as well as the management and the outcome of 13 patients with documented Pasteurella multocida infections, diagnosed in the University hospital of Crete, Greece, between 1993 and 2004. Most patients (62% were >70 years of age. Respiratory tract infections were most commonly encountered (61.5%, followed by soft-tissue infections (30.8% and septicemia (7.7 %. Underlying diseases included malignancies, bullous pemphigoid, mitral valve stenosis, coronary disease, chronic obstructive pulmonary disease and intracranial hemorrhage. Antibiotic sensitivity testing showed that all P. multocida isolates were susceptible to beta-lactams, quinolones, chloramphenicol, tetracycline and trimethoprim/sulfamethoxazole. Antibiotics were administered to all 13 patients and a clinical response was observed in 77% of them. The overall mortality rate was 23% (3/13 but only 15.4% (2/13 died from the infection. Although rare, P. multocida infections should be suspected in patients reporting animal exposure, particularly in those with chronic underlying diseases.

  16. Mechanical analysis of twelve toggle suture constructs for stabilization of coxofemoral luxations. (United States)

    Jha, Shantibhushan; Kowaleski, Michael P


    To compare the mechanical performance of 12 commonly used toggle suture constructs (TSCs). In vitro biomechanical study. Toggle suture constructs (n = 136). TSC evaluated included #5 OrthoFiber, double strand of 5 Ethibond sutures (polyethylene terephthalate suture), 80 lb monofilament nylon, or #5 FiberWire, combined with Piermattei toggle (3/32" Steinmann pin), modified Piermattei toggle (0.045" Kirschner wire), and 1/8" Securos toggle rod for a total of 12 test groups. Acute and cyclic testing were performed using a servohydraulic testing machine and load at failure and cycles to failure were determined. In acute testing, modified Piermattei TSCs failed by toggle deformation and Piermattei and Securos TSCs failed by suture breakage at the eyelet. Mean failure load of Piermattei-#5 OrthoFiber TSC (1416 ± 74 N) was significantly greater than that of Piermattei-#5 Ethibond (883 ± 38 N); both were significantly greater than all other TSCs. Only the Piermattei TSC with #5 OrthoFiber, #5 Ethibond, and 80 lb monofilament nylon did not fail during cyclic testing. A combination of the Piermattei toggle and #5 OrthoFiber or #5 Ethibond achieved a higher load at failure than all other groups, and resisted the greatest number of cycles to failure. Long-term mechanical testing of these TSCs are warranted to further define their durability. © Copyright 2012 by The American College of Veterinary Surgeons.

  17. Weight growth of triplet infants from birth to twelve years of age. (United States)

    Yokoyama, Yoshie; Pitkäniemi, Janne; Kaprio, Jaakko; Silventoinen, Karri


    We analyzed the characteristics associated with the growth in weight of Japanese triplets from birth to 12 years of age. The study included 376 mothers and their 1,128 triplet children, who were born between 1978 and 2006. Data were collected through a mailed questionnaire sent to the mothers asking for information recorded in medical records. For these births, data on triplets' weight growth, gestational age, sex, parity, maternal age at delivery, maternal height, and maternal body mass index were obtained from records in the Maternal and Child Health Handbooks and records in the school where children receive health check-ups. The weight deficit of the triplets compared to the general population of Japan remained between 10% and 17% until 12 years of age. Moreover, at 12 years of age, the differences of weight between the general population and triplets were approximately -4.75 kg for boys and -6.00 kg for girls. Very low birth weight had the strongest contribution to body weight until 8 years of age. After 8 years of age, maternal body mass index was a significant factor affecting the weight of triplets until 12 years of age.

  18. Nonperturbative beta function of twelve-flavor SU(3) gauge theory

    CERN Document Server

    Hasenfratz, Anna


    We study the discrete beta function of SU(3) gauge theory with Nf=12 massless fermions in the fundamental representation. Using an nHYP-smeared staggered lattice action and an improved gradient flow running coupling $\\tilde g_c^2(L)$ we determine the continuum-extrapolated discrete beta function up to $g_c^2 \\approx 8.2$. We observe an IR fixed point at $g_{\\star}^2 = 7.3\\left(_{-2}^{+3}\\right)$ in the $c = \\sqrt{8t} / L = 0.25$ scheme, and $g_{\\star}^2 = 7.3\\left(_{-3}^{+5}\\right)$ with c=0.3, combining statistical and systematic uncertainties in quadrature. The systematic effects we investigate include the stability of the $(a / L) \\to 0$ extrapolations, the interpolation of $\\tilde g_c^2(L)$ as a function of the bare coupling, the improvement of the gradient flow running coupling, and the discretization of the energy density. We observe that the resulting systematic errors increase dramatically upon combining smaller $c \\lesssim 0.2$ with smaller $L \\leq 12$. At the IR fixed point we measure the leading ir...

  19. Nanosurgery of cells and chromosomes using near-infrared twelve-femtosecond laser pulses. (United States)

    Uchugonova, Aisada; Lessel, Matthias; Nietzsche, Sander; Zeitz, Christian; Jacobs, Karin; Lemke, Cornelius; König, Karsten


    ABSTRACT. Laser-assisted surgery based on multiphoton absorption of near-infrared laser light has great potential for high precision surgery at various depths within the cells and tissues. Clinical applications include refractive surgery (fs-LASIK). The non-contact laser method also supports contamination-free cell nanosurgery. In this paper we describe usage of an ultrashort femtosecond laser scanning microscope for sub-100 nm surgery of human cells and metaphase chromosomes. A mode-locked 85 MHz Ti:Sapphire laser with an M-shaped ultrabroad band spectrum (maxima: 770  nm/830  nm) and an in situ pulse duration at the target ranging from 12 fs up to 3 ps was employed. The effects of laser nanoprocessing in cells and chromosomes have been quantified by atomic force microscopy. These studies demonstrate the potential of extreme ultrashort femtosecond laser pulses at low mean milliwatt powers for sub-100 nm surgery of cells and cellular organelles.

  20. Community Energy Systems and the Law of Public Utilities. Volume Twelve. Georgia

    Energy Technology Data Exchange (ETDEWEB)

    Feurer, D A; Weaver, C L


    A detailed description of the laws and programs of the State of Georgia governing the regulation of public energy utilities, the siting of energy generating and transmission facilities, the municipal franchising of public energy utilities, and the prescription of rates to be charged by utilities including attendant problems of cost allocations, rate base and operating expense determinations, and rate of return allowances. These laws and programs are analyzed to identify impediments which they may present to the implementation of Integrated Community Energy Systems (ICES). This report is one of fifty-one separate volumes which describe such regulatory programs at the Federal level and in each state as background to the report entitled Community Energy Systems and the Law of Public Utilities - Volume One: An Overview. This report also contains a summary of a strategy described in Volume One - An Overview for overcoming these impediments by working within the existing regulatory framework and by making changes in the regulatory programs to enhance the likelihood of ICES implementation.

  1. Twelve years of the Brazilian External Quality Assessment Program in Immunohematology: benefits of the program. (United States)

    Melo, Laércio; Pellegrino, Jordão; Bianco, Celso; Castilho, Lilian


    The Brazilian External Quality Assessment Program in Immunohematology (BEQAPI) was introduced with the objective of evaluating the quality of diagnosis in immunohematology. From 1992 to 2003, proficiency tests for ABO grouping, Rh (D, C, c, E, e), K phenotyping, direct antiglobulin testing (DAT), antibody screening (AS), and antibody identification (AI) were performed. A total of 41 evaluations were carried out in 223 institutions. Over the period of 12 years, the program included 8,014 ABO typing, 8,000 RhD typing, 5,193 Rh typing (C, c, E, e), 5,101 K phenotyping, 7,939 AS, 4,533 AI, and 7,912 DATs. Erroneous responses were classified as clerical, technical, or undetermined. A substantial proportion of erroneous responses due to clerical errors occurred in ABO typing (76/76 errors), RhD typing (34/58 errors), and Rh phenotyping (50/73 errors). Technical errors occurred predominantly for weak D (91/95 errors), AS (252/301 errors), and AI (321/335 errors). Based on these results, since 1996, participants have received "Questions and Case Studies" in Immunohematology as an incentive for training and education. The results of the present study show an improvement in the performance of participants in the course of the program. We found that a well-organized external proficiency program can contribute to the improvement of quality of testing in Immunohematology.

  2. Twelve years of global observation of formaldehyde in the troposphere using GOME and SCIAMACHY sensors

    Directory of Open Access Journals (Sweden)

    I. De Smedt


    Full Text Available This work presents global tropospheric formaldehyde columns retrieved from near-UV radiance measurements performed by the GOME instrument onboard ERS-2 since 1995, and by SCIAMACHY, in operation on ENVISAT since the end of 2002. A special effort has been made to ensure the coherence and quality of the CH2O dataset covering the period 1996–2007. Optimised DOAS settings are proposed in order to reduce the impact of two important sources of error in the derivation of slant columns, namely, the polarisation anomaly affecting the SCIAMACHY spectra around 350 nm, and a major absorption band of the O4 collision complex centred near 360 nm. The air mass factors are determined from scattering weights generated using radiative transfer calculation taking into account the cloud fraction, the cloud height and the ground albedo. Vertical profile shapes of CH2O are provided by the global CTM IMAGES based on an up-to-date representation of emissions, atmospheric transport and photochemistry. A comprehensive error analysis is presented. This includes errors on the slant columns retrieval and errors on the air mass factors which are mainly due to uncertainties in the a priori profile and in the cloud properties. The major features of the retrieved formaldehyde column distribution are discussed and compared with previous CH2O datasets over the major emission regions.

  3. Detection of Potential Transit Signals in the First Twelve Quarters of Kepler Mission Data

    CERN Document Server

    Tenenbaum, Peter; Seader, Shawn; Burke, Christopher J; Christiansen, Jessie L; Rowe, Jason F; Caldwell, Douglas A; Clarke, Bruce D; Li, Jie; Quintana, Elisa V; Smith, Jeffrey C; Thompson, Susan E; Twicken, Joseph D; Borucki, William J; Batalha, Natalie M; Cote, Miles T; Haas, Michael R; Sanderfer, Dwight T; Girouard, Forrest R; Hall, Jennifer R; Ibrahim, Khadeejah; Klaus, Todd C; McCauliff, Sean D; Middour, Christopher K; Sabale, Anima; Uddin, Akm Kamal; Wohler, Bill; Barclay, Thomas; Still, Martin


    We present the results of a search for potential transit signals in the first three years of photometry data acquired by the Kepler Mission. The targets of the search include 112,321 targets which were observed over the full interval and an additional 79,992 targets which were observed for a subset of the full interval. From this set of targets we find a total of 11,087 targets which contain at least one signal which meets the Kepler detection criteria: those criteria are periodicity of the signal, an acceptable signal-to-noise ratio, and three tests which reject false positives. Each target containing at least one detected signal is then searched repeatedly for additional signals, which represent multi-planet systems of transiting planets. When targets with multiple detections are considered, a total of 18,406 potential transiting planet signals are found in the Kepler Mission dataset. The detected signals are dominated by events with relatively low signal-to-noise ratios and by events with relatively short ...

  4. Twelve tips for academic role and institutional change in distance learning. (United States)

    Delgaty, Laura


    With the uptake of distance learning (DL), which has been marginal for most clinical academics, teaching contexts, traditional power structures and relationships have changed, leaving lecturers potentially disenfranchised. DL has caused a distinct change in academic roles, but academic and institutional routines have remained unchanged. Information surrounding the changes is confusing and lacks clear guidance. To provide a pragmatic outline of roles, responsibilities, obstacles and solutions for clinical academics involved in DL. A two-year action research project was carried out examining the academic role when developing and delivering a 20 credit post graduate DL module in Clinical Education at Newcastle University. It entailed three strands which were "active" for two weeks at a time in which all activities had to be completed. Sixteen students participated in the module consisting of independent activities, facilitated discussion forums, wikis, required reading, individual and group tasks. Pedagogically, it was based on heavily on Garrison's (2012) and Salmon's (2008) work on constructivism and online communities. Institutions need a clear plan and a change of culture. Roles have emerged including: administrator, manager, team leader knowledge expert, moderator and facilitator. Universities struggle to engage staff with DL due to its unrecognised and (many academics believe) unsustainable workload. These 12 tips provide academics and managers involved in clinical education with clear guidance surrounding strategies that inform practice. New roles have emerged, work habits must be revolutionised and changes in routine must be addressed.

  5. Altered Lipid Metabolism in Recovered SARS Patients Twelve Years after Infection. (United States)

    Wu, Qi; Zhou, Lina; Sun, Xin; Yan, Zhongfang; Hu, Chunxiu; Wu, Junping; Xu, Long; Li, Xue; Liu, Huiling; Yin, Peiyuan; Li, Kuan; Zhao, Jieyu; Li, Yanli; Wang, Xiaolin; Li, Yu; Zhang, Qiuyang; Xu, Guowang; Chen, Huaiyong


    Severe acute respiratory syndrome-coronavirus (SARS-CoV) and SARS-like coronavirus are a potential threat to global health. However, reviews of the long-term effects of clinical treatments in SARS patients are lacking. Here a total of 25 recovered SARS patients were recruited 12 years after infection. Clinical questionnaire responses and examination findings indicated that the patients had experienced various diseases, including lung susceptibility to infections, tumors, cardiovascular disorders, and abnormal glucose metabolism. As compared to healthy controls, metabolomic analyses identified significant differences in the serum metabolomes of SARS survivors. The most significant metabolic disruptions were the comprehensive increase of phosphatidylinositol and lysophospha tidylinositol levels in recovered SARS patients, which coincided with the effect of methylprednisolone administration investigated further in the steroid treated non-SARS patients with severe pneumonia. These results suggested that high-dose pulses of methylprednisolone might cause long-term systemic damage associated with serum metabolic alterations. The present study provided information for an improved understanding of coronavirus-associated pathologies, which might permit further optimization of clinical treatments.

  6. Twelve Years Since Importance of Cross-Cultural Competency Recognized: Where Are We Now? (United States)

    Kessler, Remi A.; Coates, Wendy C.; Chanmugam, Arjun


    Introduction The objective of this study was to analyze the content and volume of literature that has been written on cultural competency in emergency medicine (EM) since its educational imperative was first described by the Institute of Medicine in 2002. Methods We conducted a comprehensive literature search through the PubMed portal in January 2015 to identify all articles and reviews that addressed cultural competency in EM. Articles were included in the review if cultural competency was described or if its impact on healthcare disparities or curriculum development was described. Two reviewers independently investigated all relevant articles. These articles were then summarized. Results Of the 73 abstracts identified in the initial search, only 10 met criteria for inclusion. A common theme found among these 10 articles is that cultural competency in EM is essential to reducing healthcare disparities and improving patient care. These articles were consistent in their support for cross-cultural educational advancements in the EM curriculum. Conclusion Despite the documented importance of cultural competency education in medicine, there appears to be only 10 articles over the past 12 years regarding its development and implementation in EM. This comprehensive literature review underscores the relative dearth of publications related to cultural competency in EM. The limited number of articles found is striking when compared to the growth of EM research over the same time period and can serve as a stimulus for further research in this significant area of EM education.

  7. Phenolic Composition and Antioxidant and Antiproliferative Activities of the Extracts of Twelve Common Bean (Phaseolus vulgaris L. Endemic Ecotypes of Southern Italy before and after Cooking

    Directory of Open Access Journals (Sweden)

    Maria Neve Ombra


    Full Text Available Beans are important dietary components with versatile health benefits. We analysed the extracts of twelve ecotypes of Phaseolus vulgaris in order to determine their phenolic profiles, antioxidant activity, and the in vitro antiproliferative activity. Ultra-performance liquid chromatography with diode array detector (UPLC-DAD admitted us to detect and quantify some known polyphenols, such as gallic acid, chlorogenic acid, epicatechin, myricetin, formononetin, caffeic acid, and kaempferol. The antioxidant activity (AA ranged from 1.568 ± 0.041 to 66.572 ± 3.197 mg necessary to inhibit the activity of the 2,2-diphenyl-1-picrylhydrazyl (DPPH radical by 50% (EC50. The extracts, except those obtained from the nonpigmented samples, were capable of inhibiting the proliferation of the human epithelial colorectal adenocarcinoma (Caco-2 cells, human breast cancer cells MCF-7, and A549 NSCLC cell line. Cultivars differed in composition and concentration of polyphenols including anthocyanins; cooking affected the antioxidant activity only marginally. Qualitative and quantitative differences in phenolic composition between the groups of beans influenced the biological activities; on the other hand, we did not find significant differences on the biological activities within the same variety, before and after cooking.

  8. Transfer of eleven species of the genus Burkholderia to the genus Paraburkholderia and proposal of Caballeronia gen. nov. to accommodate twelve species of the genera Burkholderia and Paraburkholderia. (United States)

    Dobritsa, Anatoly P; Samadpour, Mansour


    It has been proposed to split the genus Burkholderia into two genera according to phylogenetic clustering: (1) a genus retaining this name and consisting mainly of animal and plant pathogens and (2) the genus Paraburkholderia including so-called environmental bacteria. The latter genus name has been validly published recently. During the period between the effective and valid publications of the genus name Paraburkholderia, 16 novel species of the genus Burkholderiawere described, but only two of them can be classified as members of this genus based on the emended genus description. Analysis of traits and phylogenetic positions of the other 11 species shows that they belong to the genus Paraburkholderia, and we propose to transfer them to this genus. The reclassified species names are proposed as Paraburkholderia dipogonis comb. nov., Paraburkholderia ginsengiterrae comb. nov., Paraburkholderia humisilvae comb. nov., Paraburkholderia insulsa comb. nov., Paraburkholderia kirstenboschensis comb. nov., Paraburkholderia metalliresistens comb. nov., Paraburkholderia monticola comb. nov., Paraburkholderia panaciterrae comb. nov., Paraburkholderia rhizosphaerae comb. nov., Paraburkholderia solisilvae comb. nov. and Paraburkholderia susongensis comb. nov. The remaining three species are transferred to the new genus Caballeronia gen. nov. proposed to accommodate twelve species of the genera Burkholderia and Paraburkholderia forming a distinctive clade in phylogenetic trees. The new genus members are Caballeronia choica comb. nov., Caballeronia cordobensis comb. nov., Caballeronia glathei comb. nov., Caballeronia grimmiae comb. nov., Caballeronia humi comb. nov., Caballeronia megalochromosomata comb. nov., Caballeronia jiangsuensis comb. nov., Caballeronia sordidicola comb. nov., Caballeronia telluris comb. nov., Caballeronia terrestris comb. nov., Caballeronia udeis comb. nov., and Caballeronia zhejiangensis comb. nov.

  9. Phenolic Composition and Antioxidant and Antiproliferative Activities of the Extracts of Twelve Common Bean (Phaseolus vulgaris L.) Endemic Ecotypes of Southern Italy before and after Cooking. (United States)

    Ombra, Maria Neve; d'Acierno, Antonio; Nazzaro, Filomena; Riccardi, Riccardo; Spigno, Patrizia; Zaccardelli, Massimo; Pane, Catello; Maione, Mena; Fratianni, Florinda


    Beans are important dietary components with versatile health benefits. We analysed the extracts of twelve ecotypes of Phaseolus vulgaris in order to determine their phenolic profiles, antioxidant activity, and the in vitro antiproliferative activity. Ultra-performance liquid chromatography with diode array detector (UPLC-DAD) admitted us to detect and quantify some known polyphenols, such as gallic acid, chlorogenic acid, epicatechin, myricetin, formononetin, caffeic acid, and kaempferol. The antioxidant activity (AA) ranged from 1.568 ± 0.041 to 66.572 ± 3.197 mg necessary to inhibit the activity of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical by 50% (EC50). The extracts, except those obtained from the nonpigmented samples, were capable of inhibiting the proliferation of the human epithelial colorectal adenocarcinoma (Caco-2) cells, human breast cancer cells MCF-7, and A549 NSCLC cell line. Cultivars differed in composition and concentration of polyphenols including anthocyanins; cooking affected the antioxidant activity only marginally. Qualitative and quantitative differences in phenolic composition between the groups of beans influenced the biological activities; on the other hand, we did not find significant differences on the biological activities within the same variety, before and after cooking.

  10. Challenge of goodness: twelve humanitarian proposals based on the experience of 1991-1995 wars in Croatia and Bosnia and Herzegovina. (United States)

    Lang, S


    Based on the 1991-1995 war experience of peoples of Croatia and Bosnia and Herzegovina, I made twelve proposals regarding the following aspects of health, humanitarian work, and human rights: 1. Broadening of the WHO definition of health by including spiritual well-being (absence of hatred) in it, 2. Inclusion of the term genocide into the Index Medicus (MeSH), 3. Establishment of concepts of prevention of hate, 4. Right to a home, 5. Right of civilians to participate in defense and renewal, 6. Right to deliberation from enslavement and right to find out the fate of missing persons, 7. Global hospital, 8. Monitoring of prisoner-of-war camps, 9. Refugee camps, 10. Providing of care for the abandoned - a new category of people suffering in war, 11. Introduction of the Helping Hand concept, 12. Organization of the Red Cross Forum after the cessation of hostilities. The fundamental objective was to establish the legitimacy of honesty in practice, regulative social mechanisms, and science.

  11. Vital Signs Predict Rapid-Response Team Activation within Twelve Hours of Emergency Department Admission

    Directory of Open Access Journals (Sweden)

    James M. Walston


    Full Text Available Introduction: Rapid-response teams (RRTs are interdisciplinary groups created to rapidly assess and treat patients with unexpected clinical deterioration marked by decline in vital signs. Traditionally emergency department (ED disposition is partially based on the patients’ vital signs (VS at the time of hospital admission. We aimed to identify which patients will have RRT activation within 12 hours of admission based on their ED VS, and if their outcomes differed. Methods: We conducted a case-control study of patients presenting from January 2009 to December 2012 to a tertiary ED who subsequently had RRT activations within 12 hours of admission (early RRT activations. The medical records of patients 18 years and older admitted to a non-intensive care unit (ICU setting were reviewed to obtain VS at the time of ED arrival and departure, age, gender and diagnoses. Controls were matched 1:1 on age, gender, and diagnosis. We evaluated VS using cut points (lowest 10%, middle 80% and highest 10% based on the distribution of VS for all patients. Our study adheres to the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology guidelines for reporting observational studies. Results: A total of 948 patients were included (474 cases and 474 controls. Patients who had RRT activations were more likely to be tachycardic (odds ratio [OR] 2.02, 95% CI [1.25-3.27], tachypneic (OR 2.92, 95% CI [1.73-4.92], and had lower oxygen saturations (OR 2.25, 95% CI [1.42-3.56] upon arrival to the ED. Patients who had RRT activations were more likely to be tachycardic at the time of disposition from the ED (OR 2.76, 95% CI [1.65-4.60], more likely to have extremes of systolic blood pressure (BP (OR 1.72, 95% CI [1.08-2.72] for low BP and OR 1.82, 95% CI [1.19-2.80] for high BP, higher respiratory rate (OR 4.15, 95% CI [2.44-7.07] and lower oxygen saturation (OR 2.29, 95% CI [1.43-3.67]. Early RRT activation was associated with increased healthcare

  12. Geothermal elastomeric materials. Twelve-months progress report, October 1, 1976--September 30, 1977

    Energy Technology Data Exchange (ETDEWEB)

    Hirasuna, A.R.; Bilyeu, G.D.; Davis, D.L.; Stephens, C.A.; Veal, G.R.


    Progress is reported on efforts to develop elastomers for packer seal element applications which will survive downhole geothermal well chemistry at 260/sup 0/C (500/sup 0/F) for 24 hours. To achieve this development, a three level elastomer testing and evaluation program was established. The first level Screening Tests is a broad screening of potential candidates and with the end objective to filter out the more promising candidates for more expensive subsequent testing. The battery of tests include standard ASTM tests and a special test developed to test extrusion resistance using specimens all made from sheet stock. The second level or Simulation Tests provide a laboratory equivalent of downhole conditions using synthetic geothermal fluid. Full scale packer seals are tested under simulated operational conditions by a test fixture. The third level or In-Situ Tests which are currently in the planning, provide for testing the most favored materials in-situ in the geothermal well. A test module provides for testing of the specimen without interfacing with the well casing. A test module freely hanging on a wireline has much lower probability of causing a problem, such as becoming lodged in the well, as compared to an operational casing packer. This maximizes the number of wells (hence geothermal environments) where access can be gained and In-Situ Testing performed. During this period commercially available polymers were investigated. Most of the work centered around formulating peroxide cured Vitons and some on EPDMs, butyls, and resin cured Vitons. Of the formulations tested to date the EPDMs appear most promising and the peroxide cured Vitons next most promising. However, data is too sparse to make any firm conclusions at this time. Minor tasks were performed evaluating current commercially available elastomers used in oil tools and conceptualization of casing packer for the geothermal application.

  13. Retention and Effectiveness of Dental Sealant After Twelve Months in Iranian Children

    Directory of Open Access Journals (Sweden)



    Full Text Available Background Pit-and-fissure sealants are safe and effective ways to prevent dental caries and are considered as a part of an overall caries-preventive strategy. Dental caries are a public health problem and the most common intraoral disease affecting mankind. It is an infectious transmissible disease, with the child patient being at the highest risk. Objectives The purpose of this study was to evaluate the retention rates and effectiveness of occlusal sealants in children in Hamadan, Iran. Materials and Methods A total of 118 sealed first permanent molar teeth in 52 students (mean age, 8 years;male, 48% were evaluated for fissure sealant retention and occlusal caries status. All teeth were examined 12 months after application of sealants. Data were collected and evaluated by survival analyses methods for age at placement, patient sex, decayed/missing/filled teeth (DMFT index, fluoride history, toothbrush, tooth position in arch, and refer to dentistry. Results The overall success rate with pit-and-fissure sealant was 68.6%; in addition, 38.9% of the seals were completely retained, 38.9% partially lost, and 10.2% completely lost. There were no signs of carious lesions in 69.6% of the teeth. The factors associated with an increased risk of failure included female sex (P = 0.001 and no history of fluoride use (P < 0.01. There were no significant association between the results and patient age, tooth position in the arch, DMFT index, toothbrush, and refer to dentistry. Conclusions Although pit-and-fissure sealants are effective methods for preventing tooth caries, the low success rate of fissure sealants in current study indicated that dental sealant need to be implemented more carefully and follow-up programs are advisable.

  14. Twelve reasons to refuse the nuclear in the MDP; Douze raisons pour refuser le nucleaire dans le MDP

    Energy Technology Data Exchange (ETDEWEB)

    Bonduelle, A


    The author presents twelve reasons which show that the nuclear energy has not a place in the MDP Mechanism of Clean Development: a main loophole for the developed countries, the doubtful ''additionality'' of the nuclear, the treaty ratification is more difficult with the nuclear, the domestic energy conservation is more efficient in Europe than the nuclear development, the nuclear white elephants facing the South debts, the technology transfers are doubtful, the developing countries and the sustainable development policies are evicted from the MDP, some options are more powerful in the South, the reactors and transport networks size are unsuited, the absence of democratic control, the nuclear proliferation, the nuclear safety and the wastes. (A.L.B.)

  15. Twelve positions in a β-lactamase that can expand its substrate spectrum with a single amino acid substitution.

    Directory of Open Access Journals (Sweden)

    Hyojeong Yi

    Full Text Available The continuous evolution of β-lactamases resulting in bacterial resistance to β-lactam antibiotics is a major concern in public health, and yet the underlying molecular basis or the pattern of such evolution is largely unknown. We investigated the mechanics of the substrate fspectrum expansion of the class A β-lactamase using PenA of Burkholderia thailandensis as a model. By analyzing 516 mutated enzymes that acquired the ceftazidime-hydrolyzing activity, we found twelve positions with single amino acid substitutions (altogether twenty-nine different substitutions, co-localized at the active-site pocket area. The ceftazidime MIC (minimum inhibitory concentration levels and the relative frequency in the occurrence of substitutions did not correlate well with each other, and the latter appeared be largely influenced by the intrinsic mutational biases present in bacteria. Simulation studies suggested that all substitutions caused a congruent effect, expanding the space in a conserved structure called the omega loop, which in turn increased flexibility at the active site. A second phase of selection, in which the mutants were placed under increased antibiotic pressure, did not result in a second mutation in the coding region, but a mutation that increased gene expression arose in the promoter. This result suggests that the twelve amino acid positions and their specific substitutions in PenA may represent a comprehensive repertoire of the enzyme's adaptability to a new substrate. These mapped substitutions represent a comprehensive set of general mechanical paths to substrate spectrum expansion in class A β-lactamases that all share a functional evolutionary mechanism using common conserved residues.

  16. Changes in channel morphology over human time scales [Chapter 32 (United States)

    John M. Buffington


    Rivers are exposed to changing environmental conditions over multiple spatial and temporal scales, with the imposed environmental conditions and response potential of the river modulated to varying degrees by human activity and our exploitation of natural resources. Watershed features that control river morphology include topography (valley slope and channel...

  17. Asian Creativity, Chapter One: Creativity across Three Chinese Societies (United States)

    Wu, Jing-Jyi; Albanese, Dale


    This commentary looks at the contributions and future research implications of the four articles in this Special Issue of "Thinking Skills and Creativity" to the fields of creativity and creativity education, both in culture-specific and culture-general terms. The articles included in this Special Issue draw attention to issues of…

  18. [Herzberge - a chapter in the history of psychiatry in Berlin]. (United States)

    Walter, V


    This paper gives an outline of the work done at the insane asylum at Herzberge, Berlin, from 1893, the year when the asylum was established, through to World War 1. The then concept of therapy includes many basic principles that are now embraced in the term sociotherapy.

  19. DCAA Contract Audit Manual. Volume 1, Chapters 1 - 11 (United States)


    Systems Resident Office Hoffer, Ellen M. Sunnyvale Branch Office Hoffman, Janet A. Central Indiana Branch Office Hohmann, Ronald W. Santa Barbara Branch...CAM Production Team members for this edition included: William H. Carper , Linda Ebersbach, David Eck, Peggy Garand, Samuel J. Harker, Janice Mabey

  20. Hydrology and landscape connectivity of vernal pools. Chapter 3. (United States)

    Scott G. Liebowitz; Robert T. Brooks


    Hydrology is fundamental to wetland establishment and maintenance of wetland processes (Cole et al. 2002). Hydrology has been shown to affect, if not control, many aspects of wetland ecology, including litter decomposition and the accumulation of organic matter and sediment (Barlocher et al. 1978), the composition and productivity of pool fauna (Paton and Couch 2002),...

  1. Chapter 6. Genetic Resources: Collection, Characterization, Conservation and Documentation (United States)

    Conservation of Lens germplasm is almost entirely ex situ as seed, from wild and domestic annuals and also the wild perennials. ICARDA has the global mandate for research on lentil improvement and thus houses the world collection of Lens of 10,800 accessions and other major collections include thos...

  2. RMP Guidance for Warehouses - Chapter 9: Risk Management Plan (United States)

    Submit one RMP, including offsite consequence analysis, for all of your covered processes using the web-based RMP*eSubmit. Your RMP is then stored on EPA's Central Data Exchange (CDX) where you can access it and make changes or corrections.

  3. Twelve years of clinical practice guideline development, dissemination and evaluation in Canada (1994 to 2005

    Directory of Open Access Journals (Sweden)

    Bai Nan


    Full Text Available Abstract Background Despite the growing availability of clinical practice guidelines since the early 1990's, little is known about how guideline development and dissemination may have changed over time in Canada. This study compares Canadian guideline development, dissemination, and evaluation in two six year periods from 1994–1999 and 2000–2005. Methods Survey of guideline developers who submitted their clinical practice guidelines to the Canadian Medical Association Infobase (a Canadian guideline repository between 1994 and 2005. Survey items included information about the developers, aspects of guideline development, and dissemination and evaluation activities. Results Surveys were sent to the developers of 2341 guidelines in the CMA Infobase over the 12 year period, 1664 surveys were returned (response rate 71%. Of these, 730 unique guidelines were released from 1994–1999, and 630 were released from 2000–2005. Compared to the earlier period, more recent guidelines were being produced in English only. There has been little change in the type of organizations developing guidelines with most developed by provincial and national organizations. In the recent period, developers were more likely to report using computerized search strategies (94% versus 88%, publishing the search strategy (42% versus 34%, reaching consensus using open discussion (95% versus 78%, and evaluating effectiveness of the dissemination strategies (12% versus 6% and the impact of the CPGs on health outcomes (24% versus 5%. Recent guidelines were less likely to be based on literature reviews (94% versus 99.6% and were disseminated using fewer strategies (mean 4.78 versus 4.12. Conclusion Given that guideline development processes have improved in some areas over the past 12 years yet not in others, ongoing monitoring of guideline quality is required. Guidelines produced more recently in Canada are less likely to be based on a review of the evidence and only about

  4. Twelve thousand years of dust: the Holocene global dust cycle constrained by natural archives

    Directory of Open Access Journals (Sweden)

    S. Albani


    Full Text Available Mineral dust plays an important role in the climate system by interacting with radiation, clouds, and biogeochemical cycles. In addition, natural archives show that the dust cycle experienced variability in the past in response to global and local climate change. The compilation of the DIRTMAP paleodust datasets in the last two decades provided a target for paleoclimate models that include the dust cycle, following a time slice approach. We propose an innovative framework to organize a paleodust dataset that moves on from the positive experience of DIRTMAP and takes into account new scientific challenges, by providing a concise and accessible dataset of temporally resolved records of dust mass accumulation rates and particle grain-size distributions. We consider data from ice cores, marine sediments, loess/paleosol sequences, lake sediments, and peat bogs for this compilation, with a temporal focus on the Holocene period. This global compilation allows investigation of the potential, uncertainties and confidence level of dust mass accumulation rates reconstructions, and highlights the importance of dust particle size information for accurate and quantitative reconstructions of the dust cycle. After applying criteria that help to establish that the data considered represent changes in dust deposition, 43 paleodust records have been identified, with the highest density of dust deposition data occurring in the North Atlantic region. Although the temporal evolution of dust in the North Atlantic appears consistent across several cores and suggest that minimum dust fluxes are likely observed during the Early to mid-Holocene period (6000–8000 years ago, the magnitude of dust fluxes in these observations is not fully consistent, suggesting that more work needs to be done to synthesize datasets for the Holocene. Based on the data compilation, we used the Community Earth System Model to estimate the mass balance and variability of the global dust cycle

  5. 十二金钗判词和《红楼梦曲》悲剧意蕴的五个层次%On Levels of Tragic Implications in Verdicts to“Twelve Beauties”and in Melody of A Dream of Red Mansions

    Institute of Scientific and Technical Information of China (English)



    文章就《红楼梦》十二金钗判词及《红楼梦曲》怎样将读者引入到悲剧意蕴的情境、读者的悲剧意识怎样产生等问题,结合第五回场景营造,从十二金钗判词的文本角度进行分析,来剖析其悲剧意蕴产生的过程。%A Dream of Red Mansions is one of the four Chinese famous classical literature and a successful trag-ic novel in which the verdicts to“Twelve Beauties”in Chapter Five of the book and the melody of A Dream of Red Mansions predict the tragic fate of the female characters in the story. The paper tends to analyze the pro-cess of the tragedy from the verdict language together with the scenes in the fifth chapter of the book.

  6. Impacts of Extreme Events on Human Health. Chapter 4 (United States)

    Bell, Jesse E.; Herring, Stephanie C.; Jantarasami, Lesley; Adrianopoli, Carl; Benedict, Kaitlin; Conlon, Kathryn; Escobar, Vanessa; Hess, Jeremy; Luvall, Jeffrey; Garcia-Pando, Carlos Perez; Quattrochi, Dale; Runkle, Jennifer; Schreck, Carl J., III


    Increased Exposure to Extreme Events Key Finding 1: Health impacts associated with climate-related changes in exposure to extreme events include death, injury, or illness; exacerbation of underlying medical conditions; and adverse effects on mental health[High Confidence]. Climate change will increase exposure risk in some regions of the United States due to projected increases in the frequency and/or intensity of drought, wildfires, and flooding related to extreme precipitation and hurricanes [Medium Confidence].Disruption of Essential Infrastructure Key Finding 2: Many types of extreme events related to climate change cause disruption of infrastructure, including power, water, transportation, and communication systems, that are essential to maintaining access to health care and emergency response services and safeguarding human health [High Confidence].Vulnerability to Coastal Flooding Key Finding 3: Coastal populations with greater vulnerability to health impacts from coastal flooding include persons with disabilities or other access and functional needs, certain populations of color, older adults, pregnant women and children, low-income populations, and some occupational groups [High Confidence].Climate change will increase exposure risk to coastal flooding due to increases in extreme precipitation and in hurricane intensity and rainfall rates, as well as sea level rise and the resulting increases in storm surge.

  7. Fundamentals of Physics, Extended, Chapters 1 - 45 , Enhanced Problems Version (United States)

    Halliday, David; Resnick, Robert; Walker, Jearl


    No other book on the market today can match the success of Halliday, Resnick and Walker's Fundamentals of Physics! In a breezy, easy-to-understand style the book offers a solid understanding of fundamental physics concepts, and helps readers apply this conceptual understanding to quantitative problem solving. The extended edition provides coverage of developments in Physics in the last 100 years, including: Einstein and Relativity, Bohr and others and Quantum Theory, and the more recent theoretical developments like String Theory. This book offers a unique combination of authoritative content and stimulating applications.

  8. Occurrence and abundance of ants, reptiles, and mammals: Chapter 7 (United States)


    Sagebrush (Artemisia spp.)- associated wildlife are threatened by habitat loss and fragmentation and by impacts associated with anthropogenic disturbances, including energy development. Understanding how species of concern as well as other wildlife including insects, reptiles, and mammals respond to type and spatial scale of disturbance is critical to managing future land uses and identifying sites that are important for conservation. We developed statistical models to describe species occurrence or abundance, based on area searches in 7.29-ha survey blocks, across the Wyoming Basins Ecoregional Assessment (WBEA) area for six shrub steppe-associated species: harvester ant (Pogonomyrmex spp.), thatch ant (Formica spp.), short-horned lizard (Phrynosoma hernandesi), white-tailed jackrabbit (Lepus townsendii), cottontail (Sylvilagus spp.) and least chipmunk (Tamius minimus). We modeled patterns in occupancy or abundance relative to multi-scale measures of vegetation type and pattern, abiotic site characteristics, and anthropogenic disturbance factors. Sagebrush habitat was a strong predictor of occurrence for shorthorned lizards and white-tailed jackrabbits, but weak for the other four species. Vegetation and abiotic characteristics were strong determinants of species occurrence, although the scale of response was not consistent among species. All species, with the exception of the short-horned lizard, responded to anthropogenic disturbance, although responses again varied as a function of scale and direction (negative and positive influences). Our results improve our understanding of how environmental and anthropogenic factors affect species distributions across the WBEA area and facilitate a multi-species approach to management of this sagebrush ecosystem.

  9. Chapter 8. Evolution and development in the cavefish Astyanax. (United States)

    Jeffery, William R


    The teleost Astyanax mexicanus is a single species consisting of two radically different forms: a sighted pigmented surface-dwelling form (surface fish) and a blind depigmented cave-dwelling form (cavefish). The two forms of Astyanax have favorable attributes, including descent from a common ancestor, ease of laboratory culture, and the ability to perform genetic analysis, permitting their use as a model system to explore questions in evolution and development. Here, we review current research on the molecular, cellular, and developmental mechanisms underlying the loss of eyes and pigmentation in Astyanax cavefish. Although functional eyes are lacking in adults, cavefish embryos begin to develop eye primordia, which subsequently degenerate. The major cause of eye degeneration appears to be apoptotic cell death of the lens, which prevents the growth of other optic tissues, including the retina. Ultimately, the loss of the eye is the cause of craniofacial differences between cavefish and surface fish. Lens apoptosis is induced by enhanced activity of the Hedgehog signaling system along the cavefish embryonic midline. The absence of melanin pigmentation in cavefish is due to a block in the ability of undifferentiated melanoblasts to accumulate L-tyrosine, the precursor of L-DOPA and melanin, in melanosomes. Genetic analysis has shown that this defect is caused by a hypomorphic mutation in the p/oca2 gene encoding an integral melanosomal membrane protein. We discuss how current studies of eye and pigment regression have revealed some of the mechanisms in which cavefish development has been changed during evolution.

  10. Vegetation ecogeomorphology, dynamic equilibrium, and disturbance: chapter 7 (United States)

    Hupp, Cliff R.


    Early ecologists understood the need to document geomorphic form and process to explain plant species distributions. Although this relationship has been acknowledged for over a century, with the exception of a few landmark papers, only the past few decades have experienced intensive research on this interdisciplinary topic. Here the authors provide a summary of the intimate relations between vegetation and geomorphic/process on hillslopes and fluvial systems. These relations are separated into systems (primarily fluvial) in dynamic equilibrium and those that are in nonequilibrium conditions including the impacts of various human disturbances affecting landforms, geomorphic processes, and interrelated, attendant vegetation patterns and processes. The authors conclude with a conceptual model of stream regime focusing on sediment deposition, erosion, and equilibrium that can be expanded to organize and predict vegetation patterns and life history strategies.

  11. Orthodontics in 3 millennia. Chapter 3: The professionalization of orthodontics. (United States)

    Wahl, Norman


    In the 1930s, creative thinkers in orthodontics began to more openly question the status quo. Apprenticeships had given way to formal instruction, and proprietary schools bowed to graduate university programs, including some taught or headed by women. The MD degree was gradually replaced by the MS as the focus of orthodontics zoomed out from teeth to the total patient. Angle's dogmatic stance against extraction was challenged successfully by his last disciple, Tweed, and another of Angle's pupils, Broadbent, developed that century's most important diagnostic aid, the cephalometer, which opened the door to Brodie's landmark growth studies and Downs's cephalometric analysis. Dentistry's first specialty organization, the Society of Orthodontists, was formed in 1900, and the first specialty journals appeared.

  12. Organophosphorus and carbamate pesticides. Chapter 12 in Handbook of Ecotoxicology (United States)

    Hill, Elwood F.; Hoffman, David J.; Rattner, Barnett A.; Burton, G. Allen; Cairns, John


    Organophosphorus and carbamate pesticides are used throughout the world to control a large variety of insects and other invertebrates, fungi, birds, mammals, and herbaceous plants. Over 100 different organophosphorus and carbamate chemicals are registered in the U.S. alone for use in thousands of products applied to widely diverse habitats including agricultural crops, forests, rangelands, wetlands, towns, and cities. These applications are estimated to be nearly 200 million acre-treatments (i.e., number of acres treated corrected for number of treatments) per year to control nuisance, depradating, and disease-bearing invertebrates and vertebrates, and to maintain landscape aesthetics. Except for mosquito control, most applications target terrestrial habitat. Due to drift or run-off, pesticide and degrades are inevitably detected in soils and water that are fundamental to the primary productivity of ecosystems. Thus, critical life-giving systems are frequently contaminated with organophosphorus and carbamate pesticides, however briefly, each year.

  13. Optimization of radio telemetry receiving systems: Chapter 5.2 (United States)

    Evans, Scott D.; Stevenson, John R.; Adams, Noah S.; Beeman, John W.; Eiler, John H.


    Telemetry provides a powerful and flexible tool for studying fish and other aquatic animals, and its use has become increasingly commonplace. However, telemetry is gear intensive and typically requires more specialized knowledge and training than many other field techniques. As with other scientific methods, collecting good data is dependent on an understanding of the underlying principles behind the approach, knowing how to use the equipment and techniques properly, and recognizing what to do with the data collected. This book provides a road map for using telemetry to study aquatic animals, and provides the basic information needed to plan, implement, and conduct a telemetry study under field conditions. Topics include acoustic or radio telemetry study design, tag implantation techniques, radio and acoustic telemetry principles and case studies, and data management and analysis.

  14. Decorative carving in Chapter-House of Dominican Monastery in Cracow

    Directory of Open Access Journals (Sweden)

    Marek Walczak


    Full Text Available The history of the chapter house of the Dominican Friars in Cracow is not known in greater detail. Only two medieval documents with a mention of it are known. In in capitulo fratrum ordinis Praedicatorum Cracoviae of 1244 an endowment for the Cistercian monastery in Mogiła was confirmed. In Cracovie in capitulo fratrum predicatorum of 1306 the purchase of land in Dąbie, near Cracow, was certified. Marcin Szyma estimated that these notes cannot be ascribed to one building, which means that there were two gathering places for monks, one built after the other. Szyma locates the oldest chapter-house in the site of today’s sacristy and links it with a brick wall with a biforium window and portal remains, found in the western wall of the building. The older record marks terminus ante quern, and comparative chronology and analysis of style point to 1240s as the date of extension of the house. A new chapter house was built in Szyma’s assessment at the end of that century, and certainly before 1306. The building has fairly rich decorative carving, infrequently mentioned in historical records. The portal in the western wall of the chapter house has had three preserved, if tumbledown, consoles carved in yellowish, fine-grained sandstone. The closest analogies to these decorations are to be found in edifices built for the last members of the Premyslids dynasty, especially for king Premyslav Otokar II in the third quarter of the 13th century. In works connected with the “Premyslids building school” compact, block-like shapes of caps, ‘coated’ with tiny leaves and decorative ‘crowns’ at rib base were fairly common. Consoles in a portal of the oldest fragment of Śpilberk in Brno or chapels in the castles in Bezdez, Horsovsky Tyn, Zvikov and Buchlov are of special importance for these considerations. Czech examples most often employ a variety of flora, yet, even here, in the portal caps of the monastery in Hradiśte on Jizerou (ca 1260 we

  15. Chapter 2. Vulnerability of marine turtles to climate change. (United States)

    Poloczanska, Elvira S; Limpus, Colin J; Hays, Graeme C


    Marine turtles are generally viewed as vulnerable to climate change because of the role that temperature plays in the sex determination of embryos, their long life history, long age-to-maturity and their highly migratory nature. Extant species of marine turtles probably arose during the mid-late Jurassic period (180-150 Mya) so have survived past shifts in climate, including glacial periods and warm events and therefore have some capacity for adaptation. The present-day rates of increase of atmospheric greenhouse gas concentrations, and associated temperature changes, are very rapid; the capacity of marine turtles to adapt to this rapid change may be compromised by their relatively long generation times. We consider the evidence and likely consequences of present-day trends of climate change on marine turtles. Impacts are likely to be complex and may be positive as well as negative. For example, rising sea levels and increased storm intensity will negatively impact turtle nesting beaches; however, extreme storms can also lead to coastal accretion. Alteration of wind patterns and ocean currents will have implications for juveniles and adults in the open ocean. Warming temperatures are likely to impact directly all turtle life stages, such as the sex determination of embryos in the nest and growth rates. Warming of 2 degrees C could potentially result in a large shift in sex ratios towards females at many rookeries, although some populations may be resilient to warming if female biases remain within levels where population success is not impaired. Indirectly, climate change is likely to impact turtles through changes in food availability. The highly migratory nature of turtles and their ability to move considerable distances in short periods of time should increase their resilience to climate change. However, any such resilience of marine turtles to climate change is likely to be severely compromised by other anthropogenic influences. Development of coastlines may

  16. Packaging and transportation manual. Chapter on the packaging and transportation of hazardous and radioactive waste

    Energy Technology Data Exchange (ETDEWEB)



    The purpose of this chapter is to outline the requirements that Los Alamos National Laboratory employees and contractors must follow when they package and ship hazardous and radioactive waste. This chapter is applied to on-site, intra-Laboratory, and off-site transportation of hazardous and radioactive waste. The chapter contains sections on definitions, responsibilities, written procedures, authorized packaging, quality assurance, documentation for waste shipments, loading and tiedown of waste shipments, on-site routing, packaging and transportation assessment and oversight program, nonconformance reporting, training of personnel, emergency response information, and incident and occurrence reporting. Appendices provide additional detail, references, and guidance on packaging for hazardous and radioactive waste, and guidance for the on-site transport of these wastes.

  17. Hepatology – Guidelines on Parenteral Nutrition, Chapter 16

    Directory of Open Access Journals (Sweden)

    Plauth, M.


    Full Text Available Parenteral nutrition (PN is indicated in alcoholic steatohepatitis (ASH and in cirrhotic patients with moderate or severe malnutrition. PN should be started immediately when sufficientl oral or enteral feeding is not possible. ASH and cirrhosis patients who can be sufficiently fed either orally or enterally, but who have to abstain from food over a period of more than 12 hours (including nocturnal fasting should receive basal glucose infusion (2–3 g/kg/d. Total PN is required if such fasting periods last longer than 72 h. PN in patients with higher-grade hepatic encephalopathy (HE; particularly in HE IV° with malfunction of swallowing and cough reflexes, and unprotected airways. Cirrhotic patients or patients after liver transplantation should receive early postoperative PN after surgery if they cannot be sufficiently rally or enterally nourished. No recommendation can be made on donor or organ conditioning by parenteral administration of glutamine and arginine, aiming at minimising ischemia/reperfusion damage. In acute liver failure artificial nutrition should be considered irrespective of the nutritional state and should be commenced when oral nutrition cannot be restarted within 5 to 7 days. Whenever feasible, enteral nutrition should be administered via a nasoduodenal feeding tube.

  18. Complications and Monitoring – Guidelines on Parenteral Nutrition, Chapter 11

    Directory of Open Access Journals (Sweden)

    Working group for developing the guidelines for parenteral nutrition of The German Association for Nutritional Medicine


    Full Text Available Compared to enteral or hypocaloric oral nutrition, the use of PN (parenteral nutrition is not associated with increased mortality, overall frequency of complications, or longer length of hospital stay (LOS. The risk of PN complications (e.g. refeeding-syndrome, hyperglycaemia, bone demineralisation, catheter infections can be minimised by carefully monitoring patients and the use of nutrition support teams particularly during long-term PN. Occuring complications are e.g. the refeeding-syndrome in patients suffering from severe malnutrition with the initiation of refeeding or metabolic, hypertriglyceridemia, hyperglycaemia, osteomalacia and osteoporosis, and hepatic complications including fatty liver, non-alcoholic fatty liver disease, cholestasis, cholecystitis, and cholelithiasis. Efficient monitoring in all types of PN can result in reduced PN-associated complications and reduced costs. Water and electrolyte balance, blood sugar, and cardiovascular function should regularly be monitored during PN. Regular checks of serum electrolytes and triglycerides as well as additional monitoring measures are necessary in patients with altered renal function, electrolyte-free substrate intake, lipid infusions, and in intensive care patients. The metabolic monitoring of patients under long-term PN should be carried out according to standardised procedures. Monitoring metabolic determinants of bone metabolism is particularly important in patients receiving long-term PN. Markers of intermediary, electrolyte and trace element metabolism require regular checks.

  19. Biological soil crusts as soil stabilizers: Chapter 16 (United States)

    Belnap, Jayne; Buedel, Burkhard; Weber, Bettina; Buedel, Burkhard; Belnap, Jayne


    Soil erosion is of particular concern in dryland regions, as the sparse cover of vascular plants results in large interspaces unprotected from the erosive forces of wind and water. Thus, most of these soil surfaces are stabilized by physical or biological soil crusts. However, as drylands are extensively used by humans and their animals, these crusts are often disturbed, compromising their stabilizing abilities. As a result, approximately 17.5% of the global terrestrial lands are currently being degraded by wind and water erosion. All components of biocrusts stabilize soils, including green algae, cyanobacteria, fungi, lichens, and bryophytes, and as the biomass of these organisms increases, so does soil stability. In addition, as lichens and bryophytes live atop the soil surface, they provide added protection from raindrop impact that cyanobacteria and fungi, living within the soil, cannot. Much research is still needed to determine the relative ability of individual species and suites of species to stabilize soils. We also need a better understanding of why some individuals or combination of species are better than others, especially as these organisms become more frequently used in restoration efforts.

  20. A chapter a day: Association of book reading with longevity. (United States)

    Bavishi, Avni; Slade, Martin D; Levy, Becca R


    Although books can expose people to new people and places, whether books also have health benefits beyond other types of reading materials is not known. This study examined whether those who read books have a survival advantage over those who do not read books and over those who read other types of materials, and if so, whether cognition mediates this book reading effect. The cohort consisted of 3635 participants in the nationally representative Health and Retirement Study who provided information about their reading patterns at baseline. Cox proportional hazards models were based on survival information up to 12 years after baseline. A dose-response survival advantage was found for book reading by tertile (HRT2 = 0.83, p Book reading contributed to a survival advantage that was significantly greater than that observed for reading newspapers or magazines (tT2 = 90.6, p book readers, book readers had a 23-month survival advantage at the point of 80% survival in the unadjusted model. A survival advantage persisted after adjustment for all covariates (HR = .80, p book readers experienced a 20% reduction in risk of mortality over the 12 years of follow up compared to non-book readers. Cognition mediated the book reading-survival advantage (p = 0.04). These findings suggest that the benefits of reading books include a longer life in which to read them.

  1. Gastroenterology – Guidelines on Parenteral Nutrition, Chapter 15

    Directory of Open Access Journals (Sweden)

    Schulz, R. J.


    Full Text Available In patients with Crohn's disease and ulcerative colitis parenteral nutrition (PN is indicated when enteral nutrition is not possible or should be avoided for medical reasons. In Crohn's patients PN is indicated when there are signs/symptoms of ileus or subileus in the small intestine, scars or intestinal fistulae. PN requires no specific compounding for chronic inflammatory bowel diseases. In both diseases it should be composed of 55–60% carbohydrates, 25–30% lipids and 10–15% amino acids. PN helps in the correction of malnutrition, particularly the intake of energy, minerals, trace elements, deficiency of calcium, vitamin D, folic acid, vitamin B12, and zinc. Enteral nutrition is clearly superior to PN in severe, acute pancreatitis. An intolerance to enteral nutrition results in an indication for total PN in complications such as pseudocysts, intestinal and pancreatic fistulae, and pancreatic abscesses or pancreatic ascites. If enteral nutrition is not possible, PN is recommended, at the earliest, 5 days after admission to the hospital. TPN should not be routinely administered in mild acute pancreatitis or nil by moth status <7 days, due to high costs and an increased risk of infection. The energy requirements are between 25 and 35 kcal/kg body weight/day. A standard solution including lipids (monitoring triglyceride levels! can be administered in acute pancreatitis. Glucose (max. 4–5 g/kg body weight/day and amino acids (about 1.2–1.5 g/kg body weight/day should be administered and the additional enrichment of TPN with glutamine should be considered in severe, progressive forms of pancreatitis.

  2. Chapter 39: an historical overview of British neurology. (United States)

    Rose, F Clifford


    In the UK, neurology stemmed from general (internal) medicine rather than psychiatry. In 1886 the Neurological Society of London was founded, with Hughlings Jackson as its first President. After World War I, Kinnier Wilson was made Physician in Charge of the first independent department of neurology, which was at Westminster Hospital in London. Although before the 17th century there were British doctors who took an interest in diseases of the nervous system, e.g. Gilbertus Anglicus (c. 1230), who distinguished epilepsy from apoplexy, and Bartholomeus Anglicus, whose encyclopedia (c. 1260) provided the first picture of a dissection printed in English, John of Gaddesden (1280-1361) was the first in Britain to produce a manuscript on neurological disorders. Thomas Willis (1621-1675) was the founder of Neurology, being the first to use the term, and was also the leader of the first multidisciplinary team in neurological science, helping to shift attention from the chambers of the brain to the brain substance itself. He wrote seven books, all but the last in Latin, and his second one, Cerebri anatome (1664) was the first on the nervous system to include the brain, spinal cord and peripheral nerves, introducing such new terms as lentiform body, corpus striatum, optic thalamus, inferior olives and peduncles. Most of his neurology was in his fifth book, De anima brutorum (1672). Before Willis the brain was a mystery, but his work laid the foundations for neurological advances. After the 17th century of William Harvey and Thomas Sydenham and the 18th century of William Heberden and Robert Whytt there followed the 19th century of James Parkinson (1755-1824), John Cooke (1756-1838), Sir Charles Bell (1774-1842), Marshall Hall (1790-1856) and Bentley Todd (1809-1860). Besides its "Father," Hughlings Jackson, the giants who established the unique superiority of British neurology were Sir William Gowers, Sir David Ferrier, Kinnier Wilson, Sir Gordon Holmes and Sir Charles

  3. Capítulo 7 - Zigomicose Chapter 7 - Zygomycosis

    Directory of Open Access Journals (Sweden)

    Cecília Bittencourt Severo


    Full Text Available A zigomicose (mucormicose é uma infecção rara, mas altamente invasiva, causada por fungos da ordem Mucorales (gêneros Rhizopus, Mucor, Rhizomucor, Absidia, Apophysomyces, Saksenaea, Cunninghamella, Cokeromyces e Syncephalastrum. Esse tipo de infecção é usualmente associado a doenças hematológicas, cetoacidose diabética e transplante de órgãos. A apresentação clínica mais frequente é a mucormicose rinocerebral, com ou sem envolvimento pulmonar. A zigomicose pulmonar ocorre mais frequentemente em pacientes com neutropenia profunda e prolongada e pode se apresentar como infiltrado lobar ou segmentar, nódulos isolados, lesões cavitárias, hemorragia ou infarto. As manifestações clínicas e radiológicas são na maioria dos casos indistinguíveis daquelas associadas com aspergilose invasiva. Este artigo descreve as características gerais da zigomicose pulmonar, com ênfase no diagnóstico laboratorial, e ilustra a morfologia de algumas lesões.Zygomycosis (mucormycosis is a rare but highly invasive infection caused by fungi belonging to the order Mucorales, which includes the genera Rhizopus, Mucor, Rhizomucor, Absidia, Apophysomyces, Saksenaea, Cunninghamella, Cokeromyces and Syncephalastrum. This type of infection is usually associated with hematologic diseases, diabetic ketoacidosis and organ transplantation. The most common form of presentation is rhinocerebral mucormycosis, with or without pulmonary involvement. Pulmonary zygomycosis is more common in patients with profound, prolonged neutropenia and can present as segmental or lobar infiltrates, isolated nodules, cavitary lesions, hemorrhage or infarction. The clinical and radiological manifestations are often indistinguishable from those associated with invasive aspergillosis. This article describes the general characteristics of pulmonary zygomycosis, emphasizing laboratory diagnosis, and illustrates the morphology of some lesions.

  4. Conceptualizing and communicating ecological river restoration: Chapter 2 (United States)

    Jacobson, Robert B.; Berkley, Jim


    We present a general conceptual model for communicating aspects of river restoration and management. The model is generic and adaptable to most riverine settings, independent of size. The model has separate categories of natural and social-economic drivers, and management actions are envisioned as modifiers of naturally dynamic systems. The model includes a decision-making structure in which managers, stakeholders, and scientists interact to define management objectives and performance evaluation. The model depicts a stress to the riverine ecosystem as either (1) deviation in the regimes (flow, sediment, temperature, light, biogeochemical, and genetic) by altering the frequency, magnitude, duration, timing, or rate of change of the fluxes or (2) imposition of a hard structural constraint on channel form. Restoration is depicted as naturalization of those regimes or removal of the constraint. The model recognizes the importance of river history in conditioning future responses. Three hierarchical tiers of essential ecosystem characteristics (EECs) illustrate how management actions typically propagate through physical/chemical processes to habitat to biotic responses. Uncertainty and expense in modeling or measuring responses increase in moving from tiers 1 to 3. Social-economic characteristics are shown in a parallel structure that emphasizes the need to quantify trade-offs between ecological and social-economic systems. Performance measures for EECs are also hierarchical, showing that selection of measures depend on participants’ willingness to accept uncertainty. The general form is of an adaptive management loop in which the performance measures are compared to reference conditions or success criteria and the information is fed back into the decision-making process.

  5. Chapter A10. Lakes and reservoirs: Guidelines for study design and sampling (United States)

    Green, William R.; Robertson, Dale M.; Wilde, Franceska D.


    The National Field Manual for the Collection of Water-Quality Data (National Field Manual, NFM) is an online report with separately published chapters that provides the protocols and guidelines by which U.S. Geological Survey personnel obtain the data used to assess the quality of the Nation’s surface-water and groundwater resources. Chapter 10 reviews limnological principles, describes the characteristics that distinguish lakes from reservoirs, and provides guidance for developing temporal and spatial sampling strategies and data-collection approaches to be used in lake and reservoir environmental investigations.

  6. Chapter 7: Renewable Energy Options and Considerations for Net Zero Installations

    Energy Technology Data Exchange (ETDEWEB)

    Booth, Samuel


    This chapter focuses on renewable energy options for military installations. It discusses typical renewable technologies, project development, and gives examples. Renewable energy can be combined with conventional energy sources to provide part or all of the energy demand at an installation. The appropriate technology mix for an installation will depend on site-specific factors such as renewable resources, energy costs, local energy policies and incentives, available land, mission compatibility, and other factors. The objective of this chapter is to provide basic background information and resources on renewable energy options for NATO leaders and energy personnel.

  7. Colour Metallography of Cast Iron - Chapter 1: Introduction (Ⅰ

    Directory of Open Access Journals (Sweden)

    Zhou Jiyang


    Full Text Available Cast iron, as a traditional metal material, has advantages of low total cost, good castability and machinability, good wear resistance and low notch sensitivity, and is still facing tough challenge in quality, property and variety of types etc. Experts and engineers studying and producing iron castings all around world extremely concern this serious challenge. Over more than 30 years, a great of research work has been carried out on how to further improve its property, expand its application and combine cast iron technology with some hi-techs (for example, computer technology. Nevertheless, cast iron is a multi-element and multi-phase alloy and has complex and variety of structures and still has great development potential in structure and property. For further studying and developing cast iron, theoretical research work is important promise, and the study on solidification process and control mechanism of graphite morphology is fundamental for improving property of cast iron and developing new type of cast iron. Metallography of cast iron normally includes two sections: liquid phase transformation and solid phase transformation. The book, Colour Metallography of Cast Iron, uses colour metallography technique to study solidification structures of cast irons: graphite, carbides, austenite and eutectics; and focuses on solidification processes. With progress of modern solidification theory, the control of material solidification process becomes important measure for improving traditional materials and developing new materials. Solidification structure not only influences mechanical and physical properties of cast iron, but also affects its internal quality. The book uses a large amount of colour photos to describe the formation of solidification structures and their relations. Crystallization phenomena, which cannot be displayed with traditional metallography, are presented and more phase transformation information is obtained from these colour

  8. Chapter 31: Common in vitro tests for allergy and immunology. (United States)

    Makhija, Melanie; O'Gorman, Maurice R G


    Allergen-specific IgE antibody is the most commonly ordered in vitro test in the practice of allergy and is used to diagnose type I hypersensitivity reactions to foods or reactivity to aeroallergens in patients with relative contraindications to skin-prick testing such as dermatographism. The Phadebas radioallergosorbent test (RAST; Pharmacia, Uppsala, Sweden) was the first assay reported for the detection of the allergen-specific IgE antibody. In a RAST, antigen (allergen) is bound to a solid phase, such as a paper disk, and then incubated with human serum. A buffer wash removes unbound serum proteins, and radiolabeled anti-human IgE is added to detect bound IgE, if present. The results are reported in arbitrary units of IgE per milliliter of serum. The term RAST was originally a brand name but it is now often used colloquially (and incorrectly) to describe any in vitro assay for allergen-specific IgE. Total serum IgE can be measured and is helpful in determining atopic presentations such as in allergic bronchopulmonary aspergillosis or in patients with persistent asthma who are candidates for monoclonal anti-IgE antibody therapy with, omalizumab. In patients with recurrent bacterial infections of the sinopulmonary tract, the basic humoral immune system testing includes measuring quantitative immunoglobulins (IgG, IgA, and IgM) and comparing them to age-matched normal ranges. Most clinical laboratories use nephelometry to measure immunoglobulin levels quantitatively. Nephelometry detects either the rate or the end point of soluble immune complex formation (the IgG in sera complexes with an anti-IgG antibody forming a classic immunoprecipitation reaction) by monitoring the scatter of transmitted light. The most common method for the screening of cellular immunodeficiency involved the measurement of the absolute and relative representation of the major lymphocyte subsets, T-cells, T-helper cells, T-cytotoxic cells, B-cells and NK-cells.

  9. Introduction to the geologic and geophysical studies of Fort Irwin, California: Chapter A in Geology and geophysics applied to groundwater hydrology at Fort Irwin, California (United States)

    Buesch, David C.


    Geologic and geophysical investigations in the vicinity of Fort Irwin National Training Center, California, have been completed in support of groundwater investigations, and are presented in eight chapters of this report. A generalized surficial geologic map along with field and borehole investigations conducted during 2010–11 provide a lithostratigraphic and structural framework for the area during the Cenozoic. Electromagnetic properties of resistivity were measured in the laboratory on hand and core samples, and compared to borehole geophysical resistivity data. These data were used in conjunction with ground-based time-domain and airborne data and interpretations to provide a framework for the shallow lithologic units and structure. Gravity and aeromagnetic maps cover areas ~4 to 5 times that of Fort Irwin. Each chapter includes hydrogeologic applications of the data or model results.

  10. 5S rDNA characterization in twelve Sciaenidae fish species (Teleostei, Perciformes: depicting gene diversity and molecular markers

    Directory of Open Access Journals (Sweden)

    Fernanda A. Alves-Costa


    Full Text Available In order to extend the genetic data on the Sciaenidae fish family, the present study had the purpose to characterize PCR-generated 5S rDNA repeats of twelve species of this group through PAGE (Polyacrylamide Gel Electrophoresis analysis. The results showed the occurrence of at least two different 5S rDNA size classes in all the species. Moreover, 5S rDNA repeats of one of the studied species - Isopisthus parvipinnis - were cloned and subjected to nucleotide sequencing and Southern blot membrane hybridization analyses, which permitted to confirm the existence of two major 5S rDNA classes. Phylogenetic analysis based on the nucleotide sequences of different 5S rDNA repeats of I. parvipinnis lead to their separation into two major clusters. These results may reflect the high dynamism that rules the evolution rate of 5S rDNA repeats. The obtained data suggest that 5S rDNA can be useful in genetic analyses to identify species-specific markers and determine relationships among species of the Sciaenidae group.

  11. Uptake of radionuclide thorium by twelve native plants grown in uranium mill tailings soils from south part of China

    Energy Technology Data Exchange (ETDEWEB)

    Yan, Xun, E-mail:


    Highlights: • Screen dominant plants grown in uranium mill tailings soils. • Quantify the content of {sup 232}Th of soil samples from uranium mill tailings. • Quantify the transfer factor, bioconcentration factor and phytoremediation factor. • Screen out the plant species capable of remediating radionuclide contaminated soils. • Guide the reuse of study area in future. - Abstract: The concentrations of thorium ({sup 232}Th) in soil from a uranium mill tailings repository in South China were analyzed. The results showed that all the soil samples were acidic and the concentrations of {sup 232}Th in all the soil samples were more than the natural radionuclide content in soil of China. Through the field investigation, twelve kinds of dominant plants were discovered. The total quantity of {sup 232}Th in the whole plant is highest in rice flat sedge. We also found that Miscanthus floridulus has the greatest transfer factor (TF) for {sup 232}Th, rice flat sedge has the greatest bioconcentration factor (BF) for {sup 232}Th. At the mean time, M. floridulus has the greatest phytoremediation factor (PF) for {sup 232}Th. On the basis of the above conclusions and the definition for hyperaccumulator, rice flat sedge and M. floridulus could be the candidates of phytoremediation for radionuclide {sup 232}Th in the soil.

  12. Videofluoroscopy of the oral phase of swallowing in eight to twelve years old children with dental malocclusion. (United States)

    Junqueira, Patricia; Costa, Milton Melciades


    The objective of this study was to describe the oral phase of swallowing in individuals with dental malocclusion and to generate data that would contribute to the rehabilitation of those patients. The study was based on the evaluation of the swallowing system through videofluoroscopy on thirty-four children of both genders, aged eight to twelve years old who present with Angle Class II and III dental malocclusions. Thirteen children of similar age and gender presenting normal dental occlusion formed the control group. The results indicated that the oral phase of swallowing is different between individuals with normal occlusion and malocclusion. Dental occlusion types Angle Class II and III did not present a swallowing pattern, independently of the amount of liquid ingested. The swallowing appeared effective in the oral phase of individuals with dental malocclusion, even though adaptations were identified. The outcome, in the absence of a single pattern and the efficiency of the adapted swallowing demonstrates, first a need for additional research investigating orofacial myofunctional treatment for patients with malocclusion and second how such analyses should focus on contributing positively to the rehabilitation of these patients.

  13. Advanced LIGO Two-Stage Twelve-Axis Vibration Isolation and Positioning Platform. Part 2: Experimental Investigation and Tests Results

    CERN Document Server

    Matichard, Fabrice; Mason, Kenneth; Mittleman, Richard; Abbott, Benjamin; Abbott, Samuel; Allwine, Eric; Barnum, Samuel; Birch, Jeremy; Biscans, Sebastien; Clark, Daniel; Coyne, Dennis; DeBra, Dan; DeRosa, Ryan; Foley, Stephany; Fritschel, Peter; Giaime, Joseph A; Gray, Corey; Grabeel, Gregory; Hanson, Joe; Hillard, Michael; Kissel, Jeffrey; Kucharczyk, Christopher; Roux, Adrien Le; Lhuillier, Vincent; Macinnis, Myron; OReilly, Brian; Ottaway, David; Paris, Hugo; Puma, Michael; Radkins, Hugh; Ramet, Celine; Robinson, Mitchell; Ruet, Laurent; Sareen, Pradeep; Shoemaker, Daivid; Stein, Andy; Thomas, Jeremy; Vargas, Michael; Warner, Jimmy


    This paper presents the results of the past seven years of experimental investigation and testing done on the two-stage twelve-axis vibration isolation platform for Advanced LIGO gravity waves observatories. This five-ton two-and-half-meter wide system supports more than a 1000 kg of very sensitive equipment. It provides positioning capability and seismic isolation in all directions of translation and rotation. To meet the very stringent requirements of Advanced LIGO, the system must provide more than three orders of magnitude of isolation over a very large bandwidth. It must bring the motion below 10^(-11) m/(Hz)^0.5 at 1 Hz and 10^(-12) m/(Hz)^0.5 at 10 Hz. A prototype of this system has been built in 2006. It has been extensively tested and analyzed during the following two years. This paper shows how the experimental results obtained with the prototype were used to engineer the final design. It highlights how the engineering solutions implemented not only improved the isolation performance but also greatl...

  14. Twelve-month safety and efficacy of inhaled fluticasone propionate in children aged 1 to 3 years with recurrent wheezing

    DEFF Research Database (Denmark)

    Bisgaard, Hans; Allen, David; Milanowski, Janusz;


    : There was no significant difference in mean adjusted growth rates between the 2 groups: 84.0 mm/year in the FP group versus 86.4 mm/year in the SCG group (difference FP-SCG: -2.4 mm/year; 95% confidence interval: -6.6 to 1.8). Growth comparisons were independent of age, gender, previous use of steroid, or whether measured......, exacerbations, and requirements for oral steroid treatment and more symptom-free days and days without use of rescue treatment. CONCLUSIONS: Twelve months of treatment with inhaled FP (100 microg twice daily) in preschool children aged 1 to 3 years with recurrent wheeze has no effect on growth and no other......OBJECTIVE: Our aim was to compare the 12-month safety and efficacy of fluticasone propionate (FP) and sodium cromoglycate (SCG) in children aged 1 to 3 years with mild to moderate recurrent wheeze. METHODS: The study was a randomized, parallel-group, open-label multicenter study of 625 children...

  15. A First Assessment of Mycobacterium tuberculosis Genetic Diversity and Drug-Resistance Patterns in Twelve Caribbean Territories

    Directory of Open Access Journals (Sweden)

    Julie Millet


    Full Text Available With the exception of some French-speaking islands, data on tuberculosis (TB in the Caribbean are scarce. In this study, we report a first assessment of genetic diversity of a convenience sample of Mycobacterium tuberculosis strains received from twelve Caribbean territories by spoligotyping and describe their drug-resistance patterns. Of the 480 isolates, 40 (8.3% isolates showed resistance to at least one anti-TB drug. The proportion of drug-resistant strains was significantly higher in The Bahamas (21.4%; P=0.02, and Guyana (27.5%; P<0.0001, while it was significantly lower in Jamaica (2.4%; P=0.03 than in other countries of the present study. Regarding genetic diversity, 104 distinct spoligotype patterns were observed: 49 corresponded to clustered strains (2 to 93 strains per cluster, while 55 remained unclustered among which 16 patterns were not reported previously. Combining the study results with regional data retrieved from the international SITVIT2 database underlined a connection between frequency of certain M. tuberculosis phylogenetic lineages and the language spoken, suggesting historical (colonial and ongoing links (trade, tourism, and migratory flows with European countries with which they shared a common past.

  16. Chemical Abundances in Twelve Red Giants of the Large Magellanic Cloud from High-Resolution Infrared Spectroscopy

    CERN Document Server

    Smith, V V; Cunha, K; Plez, B; Lambert, D L; Pilachowski, C A; Barbuy, B; Melendez, J; Balachandran, S C; Bessell, M S; Geisler, D; Hesser, J E; Winge, C


    High-resolution infrared spectra (R=50,000) have been obtained for twelve red-giant members of the LMC with the Gemini South 8.3-meter telescope plus Phoenix spectrometer. Quantitative chemical abundances of carbon-12, carbon-13, nitrogen-14, and oxygen-16 were derived from molecular lines of CO, CN, and OH, while sodium, scandium, titanium, and iron abundances were derived from neutral atomic lines. The LMC giants have masses from about 1 to 4 solar masses and span a metallicity range from [Fe/H]= -1.1 to -0.3. The program red giants all show evidence of first dredge-up mixing, with low 12C/13C ratios, and low 12C correlated with high 14N abundances. Comparisons of the oxygen-to-iron ratios in the LMC and the Galaxy indicate that the trend of [O/Fe] versus [Fe/H] in the LMC falls about 0.2 dex below the Galactic trend. Such an offset can be modeled as due to an overall lower rate of supernovae per unit mass in the LMC relative to the Galaxy, as well as a slightly lower ratio of supernovae of type II to super...

  17. HLA compatibility assessment and management of highly sensitized patients under the new kidney allocation system (KAS): A 2016 status report from twelve HLA laboratories across the U.S. (United States)

    Kamoun, M; Phelan, D; Noreen, H; Marcus, N; Klingman, L; Gebel, H M


    Twelve HLA laboratories were surveyed to assess the methods and operational issues involved to define highly sensitized patients and to assess HLA compatibility under the new kidney allocation system (KAS) in the U.S. All laboratories used single antigen bead assays both pre- and post-KAS to define both broad and allele-specific HLA antibodies. The methods and threshold used to list HLA unacceptable antigens in UNet for virtual crossmatch (vXM) and the criteria used for determining HLA compatibility varied among laboratories. Laboratories reported several limitations of the current assays including the accuracy of quantifiable antibody fluorescence values, inadequate coverage of common alleles on the bead panels, and challenges in calibrating the vXM. The new KAS has resulted in a significant surge of deceased donor organ offers requiring vXM evaluation under tight time constraints. In the post-KAS period, eight of twelve laboratories (67%) indicated that their center did not proceed to transplant based on vXM without a prospective lymphocyte crossmatch. In conclusion, HLA laboratories play a critical role in deceased donor allocation for highly sensitized patients under the new KAS. Significant opportunities exist to improve the methods used in the assessment of HLA compatibility to safely transplant highly sensitized patients.

  18. 基于ADAMS的12自由度动力总成悬置系统怠速隔振分析%Idle Vibration Isolation Analysis of Twelve Degrees of Freedom Power-train Mounting System Based on ADAMS

    Institute of Scientific and Technical Information of China (English)

    张健; 杨啟梁; 胡溧; 杨胜; 杨培刚


    This paper takes a light duty bus as study object to establish ADAMS dynamic model which includes twelve degrees of freedom powertrain mounting system of two rigid bodies of powertrain and body, and presents a method to determine engine idle excitation which combines test and theoretical calculation. The paper uses this model to carry out simulation calculation and analysis of idle vibration isolation performance of powertrain mounting system. The comparison between simulation results and test results shows that these two results agree well, indicating that the established twelve degrees of freedom ADAMS model and the engine excitation are correct.%以某轻型客车为研究对象,建立了包括动力总成和车身两个刚体的12自由度动力总成悬置系统的ADAMS动力学模型,提出了一种试验与理论计算相结合确定发动机怠速激励的方法.采用该模型对动力总成悬置系统怠速隔振性能进行了仿真计算与分析.仿真结果与试验结果对比表明二者吻合较好,说明所建立的12自由度ADAMS模型和确定的发动机激励是准确的.

  19. Chapter 1 Common Data Elements and Federal Interagency Traumatic Brain Injury Research Informatics System for TBI Research. (United States)

    Thompson, Hilaire J; Vavilala, Monica S; Rivara, Frederick P


    Despite increased attention to traumatic brain injury (TBI), there remains no specific treatment and available interventions focus rather on the prevention of secondary injury. One of the reasons posited for the lack of a successful therapy is the amalgamation of various types of injuries under the same severity category in clinical trials. Informatics approaches have been suggested as a means to develop an improved classification system for TBI. As a result of federal interagency efforts, common data elements (CDEs) for TBI have now been developed. Further, the Federal Interagency Traumatic Brain Injury Research Informatics System (FITBIR) has been created and is now available for TBI researchers to both add and retrieve data. This chapter will discuss the goals, development, and evolution of the CDEs and FITBIR and discuss how these tools can be used to support TBI research. A specific exemplar using the CDEs and lessons learned from working with the CDEs and FITBIR are included to aid future researchers.

  20. The Oregon Oceanbook. An Introduction to the Pacific Ocean off Oregon Including Its Physical Setting and Living Marine Resources. (United States)

    Parmenter, Tish; Bailey, Robert

    Developed to integrate fundamental oceanographic concepts with basic research, this book presents information about the Pacific Ocean off the coast of Oregon. Characterizations and descriptions of the marine environment from the coastline to approximately 200 miles offshore are provided for the interested public. Chapter topics include: (1) marine…