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Sample records for tu man dotu

  1. Manûtu ša Bābili = the Babylonian subdivision of the mina

    NARCIS (Netherlands)

    van der Spek, R.J.

    A new interpretation of the term Manûtu ša Bābili is presented here. It is not the exchange rate between shekels and drachmas, as was generally assumed, but it is the Babylonian subdivision ("counting") of the mina as opposed to the Greek mina. A Babylonian mina counts 30 staters, a Greek mina 25

  2. DotU and VgrG, core components of type VI secretion systems, are essential for Francisella LVS pathogenicity.

    Directory of Open Access Journals (Sweden)

    Jeanette E Bröms

    Full Text Available The Gram-negative bacterium Francisella tularensis causes tularemia, a disease which requires bacterial escape from phagosomes of infected macrophages. Once in the cytosol, the bacterium rapidly multiplies, inhibits activation of the inflammasome and ultimately causes death of the host cell. Of importance for these processes is a 33-kb gene cluster, the Francisella pathogenicity island (FPI, which is believed to encode a type VI secretion system (T6SS. In this study, we analyzed the role of the FPI-encoded proteins VgrG and DotU, which are conserved components of type VI secretion (T6S clusters. We demonstrate that in F. tularensis LVS, VgrG was shown to form multimers, consistent with its suggested role as a trimeric membrane puncturing device in T6SSs, while the inner membrane protein DotU was shown to stabilize PdpB/IcmF, another T6SS core component. Upon infection of J774 cells, both ΔvgrG and ΔdotU mutants did not escape from phagosomes, and subsequently, did not multiply or cause cytopathogenicity. They also showed impaired activation of the inflammasome and marked attenuation in the mouse model. Moreover, all of the DotU-dependent functions investigated here required the presence of three residues that are essentially conserved among all DotU homologues. Thus, in agreement with a core function in T6S clusters, VgrG and DotU play key roles for modulation of the intracellular host response as well as for the virulence of F. tularensis.

  3. Tu nos aposte protege

    DEFF Research Database (Denmark)

    Frederiksen, Britta Olrik

    2007-01-01

    Aspirationen af p, t og k i dansk er stedmoderligt behandlet af den gren af den historiske sprogforskning der bygger på skriftligt kildemateriale. Skrivemåden tu nos aposte protege for tu nos ab hoste protege 'bekyt du os mod fjenden' i en tilskrift fra anden halvdel af 1300-tallet i...

  4. Leerstoel Installaties TU Delft

    NARCIS (Netherlands)

    Luscuere, P.G.; Zeiler, W.; Cauberg, J.J.M.; van der Linden, A.C.; Dobbelsteen, A.A.J.F.

    2007-01-01

    De leerstoel Installaties aan de TU Delft heeft een lange geschiedenis. De laatste decennia heeft Peter Luscuere de leerstoel in deeltijd bezet en zo een belangrijke bijdrage geleverd aan de koppeling van Onderzoek, Onderwijs en Ondernemen. Het artikel start met een korte beschrijving van de huidige

  5. Tu proyecto de vida

    OpenAIRE

    Ramos, Georgina

    2012-01-01

    - Párrafo Inicial - Conociendo a Liliana N. - La intervención de la psicóloga Adriana - Tu proyecto de vida - Referencias - Notas de enseñanza o Resumen o Objetivos o Temas relacionados o Plan de aplicación para el aprendizaje o Análisis o Epílogo

  6. Core TuLiP

    NARCIS (Netherlands)

    Czenko, M.R.; Etalle, Sandro

    2007-01-01

    We propose CoreTuLiP - the core of a trust management language based on Logic Programming. CoreTuLiP is based on a subset of moded logic programming, but enjoys the features of TM languages such as RT; in particular clauses are issued by different authorities and stored in a distributed manner. We

  7. TU electric reactor model verification

    International Nuclear Information System (INIS)

    Willingham, C.E.; Killgore, M.R.

    1989-01-01

    Power reactor benchmark calculations using the code package CASMO-3/SIMULATE-3 have been performed for six cycles of Prairie Island Unit 1. The reload fuel designs for the selected cycles include gadolinia as a burnable absorber, natural uranium axial blankets, and increased water-to-fuel ratio. The calculated results for both low-power physics tests (boron end points, control rod worths, and isothermal temperature coefficients) and full-power operation (power distributions and boron letdown) are compared to measured plant data. These comparisons show that the TU Electric reactor physics models accurately predict important physics parameters for power reactors

  8. Modelling man-made ground to link the above- and below- ground urban domains

    NARCIS (Netherlands)

    Schokker, J.

    2017-01-01

    This report describes the results of STSM TU1206-36204. During a visit to GEUS (DK) between 23 and 27 January 2017, Jeroen Schokker (TNO-GSN, NL) has focussed on the modelling of man-made ground as a linking pin between the above- and below-ground urban domains. Key results include: • Man-made

  9. The gammaTuRC Nanomachine Mechanism and Future Applications

    Science.gov (United States)

    Riehlman, Timothy D.

    The complexity and precision of the eukaryotic cell's cytoskeletal network is unrivaled by any man-made systems, perfected by billions of years of evolution, mastering elegant processes of self-assembly, error correction, and self-repair. Understanding the capabilities of these networks will have important and far reaching applications in human medicine by aiding our understanding of developmental processes, cellular division, and disease mechanisms, and through biomimicry will provide insights for biosynthetic manufacturing at the nanoscale and across scales. My research utilizes cross species techniques from Human to the model organism of Fission Yeast to investigate the structure and mechanisms of the g-tubulin ring complex (gTuRC). The gTuRC is a highly conserved eukaryotic multiprotein complex serving as a microtubule organizing center (MTOC) responsible for microtubule nucleation through templating, regulation of dynamics, and establishment of microtubule polarity. Microtubules are 25 nm diameter dynamic flexible polymers of a/b-tubulin heterodimers that function as scaffolds, force generators, distributors, and intracellular highways. The microtubule cytoskeleton is essential for numerous fundamental cellular processes such as mitotic division of chromosomes and cell division, organelle distribution within the cell, cell signaling, and cell shape. This incredible diversity in functions is made possible in part due to molecular motor Kinesin-like proteins (Klps), which allow expansion into more specialized neural, immune, and ciliated cell functions. Combined, the MTOC, microtubules, and Klps represent ideal microtubule cytoskeleton protein (MCP) modular components for in vitro biomimicry towards generation of adaptable patterned networks for human designed applications. My research investigates the hypothesis that a mechanistic understanding of conserved MTOC gTuRC mechanisms will help us understand dynamic cellular nanomachines and their ability to self

  10. Need for Different Cutoff Values for Reading Mantoux Test with 2TU and 5TU PPD.

    Science.gov (United States)

    Ramaraj, Savitha M; Nagendra, K; Gopal, Girish; Majgi, Sumanth Mallikarjuna

    2017-09-01

    To compare the tuberculin reaction of 2 tuberculin unit (TU) with 5TU purified protein derivative (PPD) (both calibrated against RT 23) in healthy children. This was a cross sectional study done in the pediatric outpatient department of a tertiary care teaching hospital. Seventy healthy siblings of the children attending pediatric outpatient department in the age group of 1 to 12 y were enrolled. The exclusion criteria included previously diagnosed tuberculosis patients, malnutrition diagnosed according to the WHO classification, history of drug intake like steroids, recent history of measles, any skin lesions over forearm, history of fever, contact with tuberculosis and previous mantoux testing. The study was conducted wherein each child was subjected to simultaneous testing with 2TU and 5TU by standard technique. The reactions to both the tests was read at 48-72 h. Children with induration ≥10 mm were evaluated for tuberculosis by taking chest x-ray, gastric lavage or sputum smear examination for acid fast bacilli (AFB). Considering ≥10 mm induration as positive, subjects positive with 5TU were 7 (10%) and 2TU was 1(p value = 0.031); thus, there is no agreement between the two methods (McNemar's test). Comparing the mean diameter of induration of 2TU and 5TU (p PPD is not comparable to that of 5TU PPD.

  11. man theerasilp

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. MAN THEERASILP. Articles written in Bulletin of Materials Science. Volume 41 Issue 2 April 2018 pp 42. Synthesis and characterization of SPIO-loaded PEG- b -PS micelles as contrast agent for long-term nanoparticle-based MRI phantom · MAN THEERASILP WITAYA ...

  12. Unit Manning

    National Research Council Canada - National Science Library

    McGinniss, Mike

    2003-01-01

    .... This decision combines two crucial initiatives: first, transforming the Army from an individual soldier replacement system to a unit manning system that enhances cohesion and keeps trained soldiers, leaders, and commanders together longer, thereby...

  13. One-step purification of E. coli elongation factor Tu

    DEFF Research Database (Denmark)

    Knudsen, Charlotte Rohde; Clark, Brian F. C.; Degn, B

    1993-01-01

    The tuf A gene, encoding the E. coli elongation factor Tu, was cloned in the pGEX gene fusion system. Upon expression EF-Tu is fused to glutathione-S-transferase serving as a purification handle with affinity for glutathione immobilised on agarose. This allows purification of EF-Tu in a one...

  14. Teaching Tu Fu on the Night Shift.

    Science.gov (United States)

    Brady, Philip

    1995-01-01

    Describes a teacher's unsuccessful attempt to introduce the poetry of Tu Fu, a wayward bureaucrat of the T'ang dynasty, to a class of part-time students. Uses his students' resistance to this poetry as an occasion to discuss the importance of personal responses to poetry, as opposed to "correct" academic responses. (TB)

  15. Core TuLiP - Logic Programming for Trust Management

    NARCIS (Netherlands)

    Czenko, M.R.; Etalle, Sandro; Dahl, V.; Niemelä, I.

    2007-01-01

    We propose CoreTuLiP - the core of a trust management language based on Logic Programming. CoreTuLiP is based on a subset of moded logic programming, but enjoys the features of TM languages such as RT; in particular clauses are issued by different authorities and stored in a distributed manner. We

  16. Characterization of Elongation Factor Tu of Mycoplasma ovipneumoniae

    Directory of Open Access Journals (Sweden)

    Xuan Zhang, Yue-feng Chu, Ping Zhao, Peng-cheng Gao, Ying He, Nu Wang and Zhong-xin Lu*

    2013-11-01

    Full Text Available Mycoplasma ovipneumoniae is considered as an important pathogen of small ruminants, but its antigenic proteins are not well known so far. In this study, we cloned the EF-Tu gene of M. ovipneumoniae and analyzed the molecular features of the gene and its coding protein for the first time. The gene was then expressed in E.coli and the antigenicity of the coding protein was evaluated as well. The EF-Tu gene of M. ovipneumoniae is 1209 bp in length, encodes 402 amino acids, and shares the highest DNA sequence identity of 87.5% and deduced amino acid sequence identity of 97.8% with those of M. hyopneumoniae, respectively. The recombinant EF-Tu protein can react with the polyclonal antiserum of M. ovipneumoniae and can induce humoral immune responses in mice, which indicated that the EF-Tu may be used as a candidate protein in developing the technologies to control the disease.

  17. Man's Evolutionary Future

    Science.gov (United States)

    Dobzhansky, Theodosius

    1972-01-01

    Man can aspire to control his evolution and direct it towards goals which he finds good, salutary, worth living for....The one most 'natural' thing for man is to modify nature by means of his knowledge." (Author/AL)

  18. Immunocytochemical localization of the elongation factor Tu in E. coli cells

    NARCIS (Netherlands)

    Slot, J.W.; Schilstra, M.J.; Meide, P.H. van der; Posthuma, G.; Cremers, A.F.M.; Bosch, L.

    1984-01-01

    The localization of the elongation factor Tu (EF-Tu) in ultrathin cryosections of E. coli cells was determined with the electron microscope using a highly specific immunological labellin technique. EF-Tu is distributed almost homogeneously throughout the cytoplasm. Although it has often been

  19. Functional studies of elongation factor Tu from Escherichia coli : Site-directed mutagenesis and antibiotic action

    NARCIS (Netherlands)

    Krab, Ivo Maarten

    2001-01-01

    This PhD thesis describes several studies into the structure and function of Escherichia coli Elongation Factor Tu (EF-Tu). EF-Tu plays a central role in the bacterial protein synthesis machinery as the carrier of "coded building blocks" for protein synthesis, aminoacylated tRNA (aa-tRNA). Without

  20. Trust Management in P2P systems using Standard TuLiP

    NARCIS (Netherlands)

    Czenko, M.R.; Doumen, J.M.; Etalle, Sandro

    2008-01-01

    In this paper we introduce Standard TuLiP - a new logic based Trust Management system. In Standard TuLiP, security decisions are based on security credentials, which can be issued by different entities and stored at different locations. Standard TuLiP directly supports the distributed credential

  1. Trust management in P2P systems using standard TuLiP

    NARCIS (Netherlands)

    Czenko, M.; Doumen, J.M.; Etalle, S.; Karabulut, Y.; Mitchell, J.C.; Herrmann, P.; Jensen, C.D.

    2008-01-01

    In this paper we introduce Standard TuLiP - a new logic based Trust Management system. In Standard TuLiP, security decisions are based on security credentials, which can be issued by different entities and stored at different locations. Standard TuLiP directly supports the distributed credential

  2. Trust Management in P2P Systems Using Standard TuLiP

    NARCIS (Netherlands)

    Czenko, M.R.; Doumen, J.M.; Etalle, Sandro

    2008-01-01

    In this paper we introduce Standard TuLiP - a new logic based Trust Management system. In Standard TuLiP, security decisions are based on security credentials, which can be issued by different entities and stored at different locations. Standard TuLiP directly supports the distributed credential

  3. TU PATERE LEGEM QUAM IPSE FECISTI

    CERN Multimedia

    Association du personnel

    2010-01-01

    In two judgments of February 2009, the ILO Administrative Tribunal (hereafter ILOAT) upheld CERN’s contract policy. In another case having given rise to a recent judgment (3 February 2010), the same problems, in essence, were raised concerning the illegal injustice which could result from the implementation of the policy in question. This time, the Tribunal decided in favour of our colleague, basing itself on the Latin maxim tu patere legem quam ipse fecisti, according to which any authority is bound by its own rules, as long as such rules have not been amended or abrogated. In fact, the Administration had informed the complainant that his application for a long-term contract would be examined for six slots, when in fact it was examined for only one. This judgment represents a victory for the complainant, for the Staff Association and its perseverance, and also for the principle according to which any organisation must keep its word and act in good faith. It shows that, without reversing its jud...

  4. Reconstitution of Qbeta RNA replicase from a covalently bonded elongation factor Tu-Ts complex

    DEFF Research Database (Denmark)

    Brown, S; Blumenthal, T

    1976-01-01

    of these polypeptides, protein synthesis elongation factors EF-Tu and EF-Ts, can be covalently crosslinked with dimethyl suberimidate to form a complex which lacks the ability to catalyze the known host functions catalyzed by the individual elongation factors. Using a previously developed reconstitution system we have...... examined the effects of crosslinking the EF-Tu-Ts complex on reconstituted replicase activity. Renaturation is significantly more efficient when exogenously added native EF-Tu-Ts is crosslinked than when it is not. Crosslinked EF-Tu-Ts can be purified from a crude crosslinked postribosomal supernatant...... by its ability to replace EF-Tu and EF-Ts in the renaturation of denatured Qbeta replicase. A sample of Qbeta replicase with crosslinked EF-Tu-Ts replacing the individual elongation factors was prepared. Although it lacked EF-Tu and EF-Ts activities, it could initiate transcription of both poly...

  5. Purification, characterization, and sequencing of novel antimicrobial peptides, Tu-AMP 1 and Tu-AMP 2, from bulbs of tulip (Tulipa gesneriana L.).

    Science.gov (United States)

    Fujimura, Masatoshi; Ideguchi, Mineo; Minami, Yuji; Watanabe, Keiichi; Tadera, Kenjiro

    2004-03-01

    Novel antimicrobial peptides (AMP), designated Tu-AMP 1 and Tu-AMP 2, were purified from the bulbs of tulip (Tulipa gesneriana L.) by chitin affinity chromatography and reverse-phase high-performance liquid chromatography (HPLC). They bind to chitin in a reversible way. They were basic peptides having isoelectric points of over 12. Tu-AMP 1 and Tu-AMP 2 had molecular masses of 4,988 Da and 5,006 Da on MALDI-TOF MS analysis, and their extinction coefficients of 1% aqueous solutions at 280 nm were 3.3 and 3.4, respectively. Half of all amino acid residues of Tu-AMP 1 and Tu-AMP 2 were occupied by cysteine, arginine, lysine, and proline. The concentrations of peptides required for 50% inhibition (IC(50)) of the growth of plant pathogenic bacteria and fungi were 2 to 20 microg/ml. The structural characteristics of Tu-AMP 1 and Tu-AMP 2 indicated that they were novel thionin-like antimicrobial peptides, though Tu-AMP 2 was a heterodimer composes of two short peptides joined with disulfide bonds.

  6. The oldest man ever?

    DEFF Research Database (Denmark)

    Wilmoth, J; Skytthe, A; Friou, D

    1996-01-01

    This article summarizes recent findings in a case study of exceptional longevity. CM, a resident of San Rafael, California, was 114 years old in August 1996. He is the first properly verified case of a 114-year-old man in human history (although a few women have been known to live longer). Our...... is accurate. Based on the available information, it also seems a reasonable conjecture that he may be the oldest man alive today and perhaps the oldest man who has ever lived. This study documents an extreme example of human longevity and records characteristics of the man's life that may provide clues about...

  7. 1-concave basis for TU games and the library game

    NARCIS (Netherlands)

    Driessen, Theo; Khmelnitskaya, Anna Borisovna; Sales, J.

    2012-01-01

    The study of 1-convex/1-concave TU games possessing a nonempty core and for which the nucleolus is linear was initiated by Driessen and Tijs (Methods Oper. Res. 46:395–406, 1983) and Driessen (OR Spectrum 7:19–26, 1985). However, until recently appealing abstract and practical examples of these

  8. Evaluating the TU/e Lupo EL BEV performance

    NARCIS (Netherlands)

    Besselink, I.J.M.; Wang, J.; Nijmeijer, H.

    2013-01-01

    The TU/e has developed a battery electric vehicle (BEV) using a VW Lupo 3L as donor platform. The differences between the initial design calculations and actual vehicle performance are analysed. Battery charging and discharging efficiency, acceleration performance and top speed are as expected. The

  9. Whole building energy performance anomaly detection at TU/e

    NARCIS (Netherlands)

    Hensen, J.L.M.; Bynum, J.D.

    2013-01-01

    Existing buildings account for the majority of energy consumption in the building sector. Surveys of existing buildings have found an estimated 10-20% reduction in energy consumption may be feasible. Research at the Eindhoven University of Technology (TU/e) is seeking to realize this potential in

  10. A note on the nucleolus for 2-convex TU games

    NARCIS (Netherlands)

    Driessen, Theo; Hou, D.

    For 2-convex n-person cooperative TU games, the nucleolus is determined as some type of constrained equal award rule. Its proof is based on Maschler, Peleg, and Shapley’s geometrical characterization for the intersection of the prekernel with the core. Pairwise bargaining ranges within the core are

  11. Defining a Pedagogical Model: The TU Delft Online Learning Experience

    NARCIS (Netherlands)

    Ribeiro Jorge, N.; Dopper, S.M.; van Valkenburg, W.F.

    2015-01-01

    In early 2014, the Delft University of Technology (TU Delft) started an innovation program with the aim to respond even more effectively to recent developments in open and online education. Drawing on the fields of Distance Education research and the university’s vision of the “engineer of the

  12. "Det man siger er man selv..."

    DEFF Research Database (Denmark)

    Næsby, Torben; Nørgaard, Britta; Uddholm, Mats

    forhold, der er hermeneutisk, strukturelt og relationelt bestemt. Praksisviden kan ikke være objektiv i gængs forstand, men det behøver ikke at diskvalificere denne viden. Forståelse er altid knyttet til den sag og bundet til den situation man står overfor og i som professionel og som menneske....

  13. Roles of Protein Synthesis Elongation Factor EF-Tu in Heat Tolerance in Plants

    Directory of Open Access Journals (Sweden)

    Jianming Fu

    2012-01-01

    Full Text Available EF-Tu proteins of plastids, mitochondria, and the cytosolic counterpart EF-1α in plants, as well as EF-Tu proteins of bacteria, are highly conserved and multifunctional. The functions of EF-Tu include transporting the aminoacyl-tRNA complex to the A site of the ribosome during protein biosynthesis; chaperone activity in protecting other proteins from aggregation caused by environmental stresses, facilitating renaturation of proteins when conditions return to normal; displaying a protein disulfide isomerase activity; participating in the degradation of N-terminally blocked proteins by the proteasome; eliciting innate immunity and triggering resistance to pathogenic bacteria in plants; participating in transcription when an E. coli host is infected with phages. EF-Tu genes are upregulated by abiotic stresses in plants, and EF-Tu plays important role in stress responses. Expression of a plant EF-Tu gene confers heat tolerance in E. coli, maize knock-out EF-Tu null mutants are heat susceptible, and over-expression of an EF-Tu gene improves heat tolerance in crop plants. This review paper summarizes the current knowledge of EF-Tu proteins in stress responses in plants and progress on application of EF-Tu for developing crop varieties tolerant to abiotic stresses, such as high temperatures.

  14. Man of Fire.

    Science.gov (United States)

    Phipps, Helene Juarez

    1993-01-01

    The themes of Jose Clemente Orozco's murals, several of which are found on U.S. college campuses, are as relevant today as they were during the Mexican Revolution. Orozco (1883-1949) painted the world as he saw it, portraying corruption, violence, and man's inhumanity to man. (LP)

  15. N K Man

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. N K Man. Articles written in Bulletin of Materials Science. Volume 37 Issue 1 February 2014 pp 19-25. Influence of preparation conditions on superconducting properties of Bi-2223 thin films · N T Mua A Sundaresan N K Man D D Dung · More Details Abstract Fulltext PDF.

  16. The Green Man

    Science.gov (United States)

    Watson-Newlin, Karen

    2010-01-01

    The Jolly Green Giant. Robin Hood. The Bamberg Cathedral. Tales of King Arthur. Ecology. What do they have in common? What legends and ancient myths are shrouded in the tales of the Green Man? Most often perceived as an ancient Celtic symbol as the god of spring and summer, the Green Man disappears and returns year after year, century after…

  17. Planets for Man

    National Research Council Canada - National Science Library

    Dole, Stephen; Asimov, Isaac

    2007-01-01

    "Planets for Man" was written at the height of the space race, a few years before the first moon landing, when it was assumed that in the not-too-distant future human beings "will be able to travel...

  18. Manned Flight Simulator (MFS)

    Data.gov (United States)

    Federal Laboratory Consortium — The Aircraft Simulation Division, home to the Manned Flight Simulator (MFS), provides real-time, high fidelity, hardware-in-the-loop flight simulation capabilities...

  19. Rekordhind Man Ray eest

    Index Scriptorium Estoniae

    1998-01-01

    Ameerika sürrealistliku fotograafi Man Ray 1926. a. Pariisis pildistatud foto 'Must ja valge, Pariis (positiiv ja negatiiv)', mis kujutab Ray armukese Kiki de Montparnasse'i portreed, maksis New Yorgi fotooksjonil 7, 3 miljonit Eesti krooni

  20. Genetics and Man

    Science.gov (United States)

    Carter, C. O.

    1973-01-01

    Can genetic evolution be controlled by man in a manner which does not violate a civilized, humane, and democratic ethos? The genetics of health and illhealth and of normal variation are discussed with respect to this question. (PEB)

  1. Trust Management in P2P systems using Standard TuLiP

    OpenAIRE

    Czenko, M.R.; Doumen, J.M.; Etalle, Sandro

    2008-01-01

    In this paper we introduce Standard TuLiP - a new logic based Trust Management system. In Standard TuLiP, security decisions are based on security credentials, which can be issued by different entities and stored at different locations. Standard TuLiP directly supports the distributed credential storage by providing a sound and complete Lookup and Inference AlgoRithm (LIAR). In this paper we focus on (a) the language of Standard TuLiP and (b) on the practical considerations which arise when d...

  2. Det man hører, er man selv

    DEFF Research Database (Denmark)

    Svømmekjær, Heidi Frank

    2012-01-01

    Katalog til udstillingen "Det man hører, er man selv" på Mediemuseet i Odense 7. september 2012 - 15. januar 2013.......Katalog til udstillingen "Det man hører, er man selv" på Mediemuseet i Odense 7. september 2012 - 15. januar 2013....

  3. Reference Japanese man

    International Nuclear Information System (INIS)

    Tanaka, Giichiro

    1985-01-01

    To make real and accurate dose assessment method so far, it is necessitated to provide ''Reference Japanese Man'' based on anotomical, physiological and biochemical data of Japanese people instead of the Reference Man presented in ICRP Publications 23 and 30. This review describes present status of researched for the purpose of establishing of Reference Japanese Man. The Reference Japanese Man is defined as a male or female adult who lives in Japan with a Japanese life-style and food custom. His stature and body weight, and the other data was decided as mean values of male or female people of Japan. As for food custom, Japanese people take significantly smaller amount of meat and milk products than Western people, while larger intake amount of cereals and marine products such as fish or seaweeds. Weight of organs is a principal factor for internal dose assessment and mean values for living Japanese adult has been investigated and the value employable for dose assessment for organs and tissues are shown. To employ these values of Reference Japanese Man, it should be taken into account of age. Metabolic parameters should also be considered. Iodine metabolism in Japanese is quite different from that of Western people. The above-mentioned data are now tentatively employing in modification of table of MIRD method and others. (Takagi, S.)

  4. Mutation of the conserved Gly83 and Gly94 in Escherichia coli elongation factor Tu. Indication of structural pivots

    DEFF Research Database (Denmark)

    Kjaersgård, I V; Knudsen, Charlotte Rohde; Wiborg, O

    1995-01-01

    Elongation factor Tu from Escherichia coli cycles between an active conformation where GTP is bound, and an inactive conformation where GDP is bound. Between the two conformations, elongation factor Tu undergoes major structural changes. The aim of this work has been to reveal the role of two ver...... is an important pivot point in elongation factor-Tu. Udgivelsesdato: 1995-Feb-15...

  5. Symbolism in prehistoric man.

    Science.gov (United States)

    Facchini, F

    2000-12-01

    The aptitude for symbolization, characteristic of man, is revealed not only in artistic representations and funerary practices. It is exhibited by every manifestation of human activity or representation of natural phenomena that assumes or refers to a meaning. We can recognize functional symbolism (tool-making, habitative or food technology), social symbolism, (language and social communication) and spiritual symbolism (funerary practices and artistic expressions). On the basis of these concepts, research into symbolism in prehistoric man allows us to recognize forms of symbolism already in the manifestations of the most ancient humans, starting with Homo habilis (or rudolfensis). Toolmaking, social organization and organization of the territory are oriented toward survival and the life of the family group. They attest to symbolic behaviors and constitute symbolic systems by means of which man expresses himself, lives and transmits his symbolic world. The diverse forms of symbolism are discussed with reference to the different phases of prehistoric humanity.

  6. Bulletproof Black Man

    DEFF Research Database (Denmark)

    Højer, Henrik

    2016-01-01

    Netflix’ kommende serie om den sorte Marvel-helt Luke Cage lander snart – midt i de aktuelle racekonflikter i USA. I GIF-anatomien "Bulletproof Black Man" sætter Henrik Højer serien ind i dens amerikanske kontekst.......Netflix’ kommende serie om den sorte Marvel-helt Luke Cage lander snart – midt i de aktuelle racekonflikter i USA. I GIF-anatomien "Bulletproof Black Man" sætter Henrik Højer serien ind i dens amerikanske kontekst....

  7. Man - Machine Communication

    CERN Document Server

    Petersen, Peter; Nielsen, Henning

    1984-01-01

    This report describes a Man-to-Machine Communication module which together with a STAC can take care of all operator inputs from the touch-screen, tracker balls and mechanical buttons. The MMC module can also contain a G64 card which could be a GPIB driver but many other G64 cards could be used. The soft-ware services the input devices and makes the results accessible from the CAMAC bus. NODAL functions for the Man Machine Communication is implemented in the STAC and in the ICC.

  8. Transportvaneundersøgelsen - Variabeldeklaration : TU 2006-11, version 1

    DEFF Research Database (Denmark)

    Christiansen, Hjalmar

    Dette notat dokumenterer de leverede data i datasættet TU 2006-11 version 1, som omfatter data fra perioden maj 2006 til 31. december 2011. For den mest opdaterede dokumentation af nyeste TU-data henvises til vores hjemmeside. Nærværende notat følger såvidt muligt datasættet og opdateres ikke...

  9. Transportvaneundersøgelsen - Variabeldeklaration : TU 2006-12, version 1

    DEFF Research Database (Denmark)

    Christiansen, Hjalmar; Skougaard, Britt Zoëga

    Dette notat dokumenterer de leverede data i datasættet TU 2006-12 version 1, som omfatter data fra perioden maj 2006 til 31. december 2012. For den mest opdaterede dokumentation af nyeste TU-data henvises til vores hjemmeside. Nærværende notat følger så vidt muligt datasættet og opdateres ikke...

  10. Transportvaneundersøgelsen - Variabeldeklaration: TU 2006-13 version 2

    DEFF Research Database (Denmark)

    Christiansen, Hjalmar; Skougaard, Britt Zoëga

    Dette notat dokumenterer de leverede data i datasættet TU 2006-13 version 2, som omfatter data fra perioden maj 2006 til 30. april 2014. For den mest opdaterede dokumentation af nyeste TU-data henvises til vores hjemmeside. Nærværende notat følger så vidt muligt datasættet og opdateres ikke...

  11. The Danish National Travel Survey - declaration of variables : TU 2006-10, version 2

    DEFF Research Database (Denmark)

    Christiansen, Hjalmar; Haunstrup, Brian

    This record documents the reported data in the data set TU 2006-10 version 1 covering data from the period May 2006 until 30 April 2011. Please refer to our website for the most up-to-date documentation of the latest TU data. This record follows, where possible, the data set and is not updated...

  12. The Danish National Travel Survey - declaration of variables : TU 2006-13, version 2

    DEFF Research Database (Denmark)

    Christiansen, Hjalmar; Skougaard, Britt Zoëga

    This record documents the reported data in the data set TU 2006-13 version 2 covering data from the period May 2006 until 30. April 2014. Please refer to our website for the most up-to-date documentation of the latest TU data. This record follows, where possible, the data set and is not updated...

  13. Transportvaneundersøgelsen - Variabeldeklaration: TU 2006-14 version 1

    DEFF Research Database (Denmark)

    Christiansen, Hjalmar; Skougaard, Britt Zoëga

    Dette notat dokumenterer de leverede data i datasættet TU 2006-14 version 1, som omfatter data fra perioden maj 2006 til 31. december 2014. For den mest opdaterede dokumentation af nyeste TU-data henvises til vores hjemmeside. Nærværende notat følger så vidt muligt datasættet og opdateres ikke...

  14. Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis

    DEFF Research Database (Denmark)

    Villa, Elizabeth; Sengupta, Jayati; Trabuco, Leonard G.

    2009-01-01

    In translation, elongation factor Tu (EF-Tu) molecules deliver aminoacyl-tRNAs to the mRNA-programmed ribosome. The GTPase activity of EF-Tu is triggered by ribosome-induced conformational changes of the factor that play a pivotal role in the selection of the cognate aminoacyl-tRNAs. We present a 6.......7-A cryo-electron microscopy map of the aminoacyl-tRNA x EF-Tu x GDP x kirromycin-bound Escherichia coli ribosome, together with an atomic model of the complex obtained through molecular dynamics flexible fitting. The model reveals the conformational changes in the conserved GTPase switch regions...... of EF-Tu that trigger hydrolysis of GTP, along with key interactions, including those between the sarcin-ricin loop and the P loop of EF-Tu, and between the effector loop of EF-Tu and a conserved region of the 16S rRNA. Our data suggest that GTP hydrolysis on EF-Tu is controlled through a hydrophobic...

  15. The Danish National Travel Survey - declaration of variables : TU 2006-12, version 1

    DEFF Research Database (Denmark)

    Christiansen, Hjalmar; Skougaard, Britt Zoëga

    This record documents the reported data in the data set TU 2006-12 version 1 covering data from the period May 2006 until 31. December 2012. Please refer to our website for the most up-to-date documentation of the latest TU data. This record follows, where possible, the data set and is not updated...

  16. Transportvaneundersøgelsen - Variabeldeklaration : TU 2006-10, version 1

    DEFF Research Database (Denmark)

    Christiansen, Hjalmar

    Dette notat dokumenterer de leverede data i datasættet TU 2006-10 version 1, som omfatter data fra perioden maj 2006 til 31. december 2010. For den mest opdaterede dokumentation af nyeste TU-data henvises til vores hjemmeside. Nærværende notat følger såvidt muligt datasættet og opdateres ikke...

  17. The Danish National Travel Survey - declaration of variables TU 2006-12, version 2 : Documentation note

    DEFF Research Database (Denmark)

    Christiansen, Hjalmar; Skougaard, Britt Zoëga

    This record documents the reported data in the data set TU 2006-12 version 1 covering data from the period May 2006 until 3o April 2013. Please refer to our website for the most up-to-date documentation of the latest TU data. This record follows, where possible, the data set and is not updated...

  18. The Danish National Travel Survey - declaration of variables TU 2006-11, version 1

    DEFF Research Database (Denmark)

    Christiansen, Hjalmar

    This record documents the reported data in the data set TU 2006-11 version 1 covering data from the period May 2006 until 31 December 2011. Please refer to our website for the most up-to-date documentation of the latest TU data. This record follows, where possible, the data set and is not updated...

  19. The Danish National Travel Survey - declaration of variables TU 2006-11, version 2

    DEFF Research Database (Denmark)

    Christiansen, Hjalmar

    This record documents the reported data in the data set TU 2006-11 version 2 covering data from the period May 2006 until 30. April 2012. Please refer to our website for the most up-to-date documentation of the latest TU data. This record follows, where possible, the data set and is not updated...

  20. The role of Glu259 in Escherichia coli elongation factor Tu in ternary complex formation

    DEFF Research Database (Denmark)

    Nautrup Pedersen, Gitte; Rattenborg, Thomas; Knudsen, Charlotte Rohde

    1998-01-01

    Determination of the crystal structure of the ternary complex formed between elongation factor Tu:GTP and aminoacylated tRNA revealed three regions of interaction between elongation factor Tu and tRNA. The structure indicates that the conserved glutamic acid at position 271 in Thermus aquaticus EF-Tu...... could be involved in the binding of the 3' CCA-Phe end of the aminoacylated tRNA. Therefore, the corresponding residue, Glu259, of Escherichia coli EF-Tu was mutated into alanine, aspartic acid, glutamine and tyrosine, in order to substantiate the crystallographic structural evidence and to obtain...... of interaction with tRNA, while mutation to tyrosine abolished completely the interaction with tRNA. Finally, mutation to glutamine resulted in an elongation factor Tu variant behaving like the wild type. In conclusion, the environment around the site binding the CCA-Phe end of the tRNA is very restricted...

  1. Johri, Prof. Man Mohan

    Indian Academy of Sciences (India)

    Elected: 1983 Section: General Biology. Johri, Prof. Man Mohan Ph.D. (Delhi), FNA. Date of birth: 15 September 1940. Specialization: Plant Biochemistry, Molecular Biology of Plants and Genetic Engineering Address: Flat No. 32, New Cosmos CHSL, Juhu-Versova Link Road, Andheri (W), Mumbai 400 053, Maharashtra

  2. Improving Enlisted Fleet Manning

    Science.gov (United States)

    2014-07-01

    and FY totals) by rating, program, and gender for active and reserve accessions. Each quarter, the Navy holds a quarterly demand planning confer...The CS E-7, E-8, and E-9 his- torically have been undermanned at sea, but in FY 2014 the CS E-7 sea manning rate reached parity . Figure 55

  3. Man as a Species.

    Science.gov (United States)

    Solem, Alan; And Others

    Written in 1964, the document represents experimental material of the Anthropology Curriculum Study Project. The objectives of the project were to discuss the evolution of man as distinguished from the evolution of other species and as related to culture, and to emphasize human diversity. Three brief essays are presented. The first, "The…

  4. TU Electric reactor physics model verification: Power reactor benchmark

    International Nuclear Information System (INIS)

    Willingham, C.E.; Killgore, M.R.

    1988-01-01

    Power reactor benchmark calculations using the advanced code package CASMO-3/SIMULATE-3 have been performed for six cycles of Prairie Island Unit 1. The reload fuel designs for the selected cycles included gadolinia as a burnable absorber, natural uranium axial blankets and increased water-to-fuel ratio. The calculated results for both startup reactor physics tests (boron endpoints, control rod worths, and isothermal temperature coefficients) and full power depletion results were compared to measured plant data. These comparisons show that the TU Electric reactor physics models accurately predict important measured parameters for power reactors

  5. The Measure your World / Mide tu Mundo Project

    Science.gov (United States)

    Hojman, S.; Johnson, R. M.; Meymaris, K. K.; Ward, D. L.; Russell, R.; Genyuk, J.; Lagrave, M.; Henderson, S.; Ostrosky, J.; Martinez, M.

    2007-12-01

    Over 22 centuries ago Erathostenes devised a method to determine the Earth radius. Measure your World / Mide tu Mundo is a joint venture lead by Windows to the Universe/Ventanas al Universo in the United States of America, EducaRed in Chile and RedEscolar in Mexico seeking to partner teams of students, teachers and parents from the three countries in a collaborative effort to determine the Earth circumference by sharing the results of their measurements, and exchanging cultural information. Data are collected from September 29 through October 7, 2007. A report of the whole experience will be presented.

  6. The End of Man

    OpenAIRE

    Martinon, Jean-Paul

    2013-01-01

    Masculinity? This book attempts to answer this one-word question by revisiting key philosophical concepts in the construction of masculinity, not in order to re-write or debunk them again, but in order to provide a radically new departure to what masculinity means today. This new departure focuses on an understanding of sexuality and gender that is neither structured in oppositional terms (masculine-feminine, male-female, man-woman) nor in performative terms (for which the opposition remains ...

  7. Man Is a Paradox

    Institute of Scientific and Technical Information of China (English)

    王茂娟

    2009-01-01

    In the poem "Always", the author Pablo Neruda employs the first person narration to incisively reveal the paradoxical traits in human nature by exploring man in relation to love. "I" play a role shifting from a calm narrator to a furious one, and the last recovering to a mild one, which offers a multiple visual angle to observe humanity. In sum, by means of continuous changes of my inner feelings in the poem, Pablo Neruda reveals the paradoxical humanity .

  8. Man and radiation effects

    International Nuclear Information System (INIS)

    Rausch, L.

    1982-01-01

    The book describes the effects of ionizing radiation on man in a simple, popular, detailed and generally valid manner and gives a comprehensive picture of the concepts, elements, principles of function, and perspectives of medical radiobiology. Radiobiology in general is explained, and its application in research on the causes of radiolesions and radiation diseases as well as a radiotherapy and radiation protection is discussed in popular form. (orig./MG) [de

  9. Man in Society

    Institute of Scientific and Technical Information of China (English)

    单祝堂

    1994-01-01

    Men usually want to have their own way.They want to thinkand act as they like.No one,however,can have his own way all thetime.A man cannot live in society without considering the interestsof others as well as his own interests.’Society’ means a groupof people with the same laws and the same way of life.People in

  10. Reference Japanese man

    International Nuclear Information System (INIS)

    Tanaka, G.-I.; Kawamura, H.; Nakahara, Y.

    1979-01-01

    The weight of organs from autopsy cases of normal Japanese adults, children, and infants is presented for the purpose of approaching a Reference Japanese Man. The skeletal content and the daily intake of alkaline earth elements are given. A lower rate of transfer (K 2 ) to the thyroid gland of ingested radioiodine, as well as a remarkably shorter biological half-life than the data adopted by ICRP, is also proved as a result of this study. (author)

  11. Man and computer

    International Nuclear Information System (INIS)

    Fischbach, K.F.

    1981-01-01

    The discussion of cultural and sociological consequences of computer evolution is hindered by human prejudice. For example the sentence 'a computer is at best as intelligent as its programmer' veils actual developments. Theoretical limits of computer intelligence are the limits of intelligence in general. Modern computer systems replace not only human labour, but also human decision making and thereby human responsibility. The historical situation is unique. Human head-work is being automated and man is loosing function. (orig.) [de

  12. Typhoon Man-Yi

    Science.gov (United States)

    2007-01-01

    Typhoon Man-Yi was pummeling the Japanese island of Okinawa with winds between 230 and 295 kilometers per hour (125-160 knots, 144-184 miles per hour) and heavy rain on the morning of July 13, 2007, when the Moderate Resolution Imaging Spectroradiometer (MODIS) on NASA's Terra satellite captured this image. The immense storm covered hundreds of kilometers with spiraling bands of thunderstorms, though it had lost the distinctive cloud-free eye it exhibited the day before. Typhoons are common in Japan, but powerful typhoons usually strike the island nation later in the year. The Japan Meteorological Agency said that Man-Yi is the fourth typhoon of the 2007 season and may be the most powerful ever observed in the northwest Pacific in July, reported Kyodo News. The Joint Typhoon Warning Center expected the typhoon to strike Kyushu, a southern Japanese island, on July 14, and then curve northeast along the eastern shore of Japan. By the time the storm reaches Tokyo on July 15, it should be degraded to a tropical storm. As of July 13, Typhoon Man-Yi had injured eight and flooded twenty houses in Okinawa, and forced airlines to cancel hundreds of flights, said Kyodo News. The storm was expected to bring heavy rain to Japan's Pacific coast. NASA image created by Jesse Allen, using data provided courtesy of the MODIS Rapid Response team.

  13. Man-machine supervision

    International Nuclear Information System (INIS)

    Montmain, J.

    2005-01-01

    Today's complexity of systems where man is involved has led to the development of more and more sophisticated information processing systems where decision making has become more and more difficult. The operator task has moved from operation to supervision and the production tool has become indissociable from its numerical instrumentation and control system. The integration of more and more numerous and sophisticated control indicators in the control room does not necessary fulfill the expectations of the operation team. It is preferable to develop cooperative information systems which are real situation understanding aids. The stake is not the automation of operators' cognitive tasks but the supply of a reasoning help. One of the challenges of interactive information systems is the selection, organisation and dynamical display of information. The efficiency of the whole man-machine system depends on the communication interface efficiency. This article presents the principles and specificities of man-machine supervision systems: 1 - principle: operator's role in control room, operator and automation, monitoring and diagnosis, characteristics of useful models for supervision; 2 - qualitative reasoning: origin, trends, evolutions; 3 - causal reasoning: causality, causal graph representation, causal and diagnostic graph; 4 - multi-points of view reasoning: multi flow modeling method, Sagace method; 5 - approximate reasoning: the symbolic numerical interface, the multi-criteria decision; 6 - example of application: supervision in a spent-fuel reprocessing facility. (J.S.)

  14. ROMANO-WARD SYNDROME ASSOCIATED WITH TU ELECTRICAL ALTERNANS

    Directory of Open Access Journals (Sweden)

    DJAWAN

    1981-05-01

    Full Text Available A case o f the electrical alternans of t he TU wave and peri odic nega t ive U wave associated with c l ini cal symptoms , e lectrocardi ographic a nd postmortem findi ng s o f Romano- Ward Syndrome has been pres ented. No e lec ~ r o l y te d ist urbance was found t o be r esponsible for t his exceptional l y rare situation . Changes i n A-V conduct i on and left bu n• d Ie branch block could be a t tributed to the d i f f use c or onary s clero sis and s ubs equent i schemia in the myocardial c onduction t.issues . The e lectrical alternans of t he U wave or TU complex of the e lectrocardiogram i s an exceeding ly r are s i t uation without any clearly known mechanism for i ts appea rance . A case of thi s phenome no~ i n as soc iation with RomanoWard Syndrome has been presented whe rein an abnorma l ity i n A-V conduction and left bund le branch block cou ld be encountered .

  15. Doc toxin is a kinase that inactivates elongation factor Tu.

    Science.gov (United States)

    Cruz, Jonathan W; Rothenbacher, Francesca P; Maehigashi, Tatsuya; Lane, William S; Dunham, Christine M; Woychik, Nancy A

    2014-03-14

    The Doc toxin from bacteriophage P1 (of the phd-doc toxin-antitoxin system) has served as a model for the family of Doc toxins, many of which are harbored in the genomes of pathogens. We have shown previously that the mode of action of this toxin is distinct from the majority derived from toxin-antitoxin systems: it does not cleave RNA; in fact P1 Doc expression leads to mRNA stabilization. However, the molecular triggers that lead to translation arrest are not understood. The presence of a Fic domain, albeit slightly altered in length and at the catalytic site, provided a clue to the mechanism of P1 Doc action, as most proteins with this conserved domain inactivate GTPases through addition of an adenylyl group (also referred to as AMPylation). We demonstrated that P1 Doc added a single phosphate group to the essential translation elongation factor and GTPase, elongation factor (EF)-Tu. The phosphorylation site was at a highly conserved threonine, Thr-382, which was blocked when EF-Tu was treated with the antibiotic kirromycin. Therefore, we have established that Fic domain proteins can function as kinases. This distinct enzymatic activity exhibited by P1 Doc also solves the mystery of the degenerate Fic motif unique to the Doc family of toxins. Moreover, we have established that all characterized Fic domain proteins, even those that phosphorylate, target pivotal GTPases for inactivation through a post-translational modification at a single functionally critical acceptor site.

  16. Doc Toxin Is a Kinase That Inactivates Elongation Factor Tu*

    Science.gov (United States)

    Cruz, Jonathan W.; Rothenbacher, Francesca P.; Maehigashi, Tatsuya; Lane, William S.; Dunham, Christine M.; Woychik, Nancy A.

    2014-01-01

    The Doc toxin from bacteriophage P1 (of the phd-doc toxin-antitoxin system) has served as a model for the family of Doc toxins, many of which are harbored in the genomes of pathogens. We have shown previously that the mode of action of this toxin is distinct from the majority derived from toxin-antitoxin systems: it does not cleave RNA; in fact P1 Doc expression leads to mRNA stabilization. However, the molecular triggers that lead to translation arrest are not understood. The presence of a Fic domain, albeit slightly altered in length and at the catalytic site, provided a clue to the mechanism of P1 Doc action, as most proteins with this conserved domain inactivate GTPases through addition of an adenylyl group (also referred to as AMPylation). We demonstrated that P1 Doc added a single phosphate group to the essential translation elongation factor and GTPase, elongation factor (EF)-Tu. The phosphorylation site was at a highly conserved threonine, Thr-382, which was blocked when EF-Tu was treated with the antibiotic kirromycin. Therefore, we have established that Fic domain proteins can function as kinases. This distinct enzymatic activity exhibited by P1 Doc also solves the mystery of the degenerate Fic motif unique to the Doc family of toxins. Moreover, we have established that all characterized Fic domain proteins, even those that phosphorylate, target pivotal GTPases for inactivation through a post-translational modification at a single functionally critical acceptor site. PMID:24448800

  17. Man and electrotechnics today

    Energy Technology Data Exchange (ETDEWEB)

    1980-12-01

    Man and electrotechnique today - this topic was discussed by experts of the VDE (Society of German Electrotechnicians) during a podium discussion directed by the TV-journalist Ruediger Proske. The discussion was centred on the popular questions of energy supply, electronics and the technical communication systems. What are the technologies' influences on our society, how can the social results for the places of employment be estimated and what role is played here by the technicians, the industry and by economy. In the debate which was partly very heated the members showed their anxiety of the negative attitude which society has been developing towards technique to cause big problems for the future.

  18. Man and electrotechnics today

    International Nuclear Information System (INIS)

    Anon.

    1980-01-01

    Man and electrotechnique today - this topic was discussed by experts of the VDE (Society of German Electrotechnicians) during a podium discussion directed by the TV-journalist Ruediger Proske. The discussion was centred on the popular questions of energy supply, electronics and the technical communication systems. What are the technologies' influences on our society, how can the social results for the places of employment be estimated and what role is played here by the technicians, the industry and by economy. In the debate which was partly very heated the members showed their anxiety of the negative attitude which society has been developing towards technique to cause big problems for the future. (orig.) [de

  19. Constructing EuroMan

    DEFF Research Database (Denmark)

    Sandberg, Marie; Andersen, Dorte

    2008-01-01

    the regional periphery in dynamic state-centred economies. In the course of the 1980s, however, interest has shifted towards regions as motors of growth, thereby making the region an actor in its own right rather than a passive receiver of subsidies. The shift in focus can be regarded a result of so...... and approaches. Eurman is possessing the ability and will to pursue rational-strategic goals and he appears in the form of an economic agent as well as a participant in political processes. Regionalisation, identity-formation and the key characteristics of EuroMan unite in EU regional policies and New...

  20. Time and man

    CERN Document Server

    Elton, L. R. B

    1978-01-01

    Time and Man focuses on the endeavors of humans to probe the mysteries of time and to elucidate its properties. The discussions are both philosophical and factual in nature and encompass science as well as the physical sciences, biology and related disciplines (for example, evolution), and the humanities (for example, religion). Factual information is presented to help the reader gain a better understanding of the concepts associated with time.Comprised of nine chapters, this volume first considers the passage of time and the experiences which humans associate with the concept of time before r

  1. Pathways to man

    International Nuclear Information System (INIS)

    Harley, J.H.

    1980-01-01

    The study of radionuclide pathways leading to man generally has the goal of allowing us to predict human exposure from measurements of the radionuclide concentration in some segment of the environment. This modelling process provides a valuable tool in both the regulatory and health protection fields. However, most of the models in the regulatory field and in the health physics profession were designed to maximize exposure estimates. It is preferable to have scientifically defensible estimates and to add suitable safety factors at the end. Thus we are still faced with the development and validation of suitable models for many of the radionuclides of interest. The most useful models will include means of assessing variability and uncertainty. In this case variability might be considered as the differences in behavior due to age, sex or other factors in animals or man and those differences among plant species or animal species that determine their uptake factors. The uncertainty, on the other hand, would be the estimate of possible error in the experimental measurements. Model parameters would always have some variability even for site-specific cases and broad averages for population groups would have to include a factor expressing the possible variabilty and uncertainity. Thus any exposure calculation would have to be expressed with some range and valid assessments of this range are required

  2. Ecology and man's environment

    Energy Technology Data Exchange (ETDEWEB)

    Al-Naqeeb, R

    1975-01-01

    A new and exciting discipline of human ecology is in the making. It has not, perhaps fortunately, found its bearings yet and remains to date overly dependent upon the limitations of sociology, biology, engineering and the sciences for its general theory, approaches, and philosophy. A new discipline with a world view and focussed on the human being and his habitat will hopefully emerge from a rich dialectic among scientists, humanists and policy makers educated and experienced in a variety of fields and committed to man's welfare. This new discipline and its practitioner must always be open to the revelations their knowledge will bring to man through the environmental processes. The implications of public policy, science and technology of industrial and post-industrial nations are all in need of considered re-examination by us all. Since their early application in these western societies we have witnessed the general downgrading of the world's environment. An ungrading in social priorities for the development of adequate housing, jobs, medical care and education which is almost always lower in rank than they should be is needed. The role of local groups, involving a well-informed and participating citizenship, in this process of changing priorities will always remain of prime importance, but no long-range goal in a rapidly-changing landscape is possible without broad national and local planning which contains ways and means of implementation.

  3. 1958 : Manning wants markets

    International Nuclear Information System (INIS)

    Anon.

    2008-01-01

    This article described the 2 opposing views in 1958 regarding how the big Montreal refinery market should be served. While the president of Imperial Oil expressed that Montreal refineries should not be forced to use domestic feedstocks, Alberta Premier Ernest Manning urged the Borden Commission to take immediate measures to expand the market for Canadian crude oil into Montreal. Manning argued that the dependence on Venezuelan crude in the Montreal refining market would pose a danger to the stability and development of the oil industry; loss of revenue for municipal, provincial and federal governments; and, an adverse effect on Canada's trade balance with the United States. The Premier suggested that these problems could be avoided by expanding the market for Canadian crude in Ontario and Quebec, in the U.S. Midwest, and in the Pacific Northwest. In 1958, the Canadian oil industry was divided on the Montreal market issue. Other key events in 1958 were listed. Waterton was characterized as Canada's biggest gas field, with reserves of 3 trillion cubic feet. A gas discovery at Berland River was considered the largest single-well exploration find in the world, flowing 27 million cubic feet per day on 1 drillstem. Two new refineries near Vancouver and Toronto were built to raise Canadian refining capacity to 813,000 barrels per day. 1 tab., 1 fig

  4. TU Berlin Rover Family for Terrestrial Testing of Complex Planetary Mission Scenarios

    Science.gov (United States)

    Kryza, L.; Brieß, K.

    2018-04-01

    The TU Berlin has developed a family of planetary rovers for educational use and research activities. The paper will introduce these cost-effective systems, which can be used for analogue mission demonstration on Earth.

  5. Cloning and Characterization of EF-Tu and EF-Ts from Pseudomonas aeruginosa

    Directory of Open Access Journals (Sweden)

    Stephanie O. Palmer

    2013-01-01

    Full Text Available We have cloned genes encoding elongation factors EF-Tu and EF-Ts from Pseudomonas aeruginosa and expressed and purified the proteins to greater than 95% homogeneity. Sequence analysis indicated that P. aeruginosa EF-Tu and EF-Ts are 84% and 55% identical to E. coli counterparts, respectively. P. aeruginosa EF-Tu was active when assayed in GDP exchange assays. Kinetic parameters for the interaction of EF-Tu with GDP in the absence of EF-Ts were observed to be = 33 μM, = 0.003 s−1, and the specificity constant was  s−1 μM−1. In the presence of EF-Ts, these values were shifted to = 2 μM, = 0.005 s−1, and the specificity constant was  s−1 μM−1. The equilibrium dissociation constants governing the binding of EF-Tu to GDP ( were 30–75 nM and to GTP ( were 125–200 nM. EF-Ts stimulated the exchange of GDP by EF-Tu 10-fold. P. aeruginosa EF-Tu was active in forming a ternary complex with GTP and aminoacylated tRNA and was functional in poly(U-dependent binding of Phe-tRNAPhe at the A-site of P. aeruginosa ribosomes. P. aeruginosa EF-Tu was active in poly(U-programmed polyphenylalanine protein synthesis system composed of all P. aeruginosa components.

  6. A generalized Tu formula and Hamiltonian structures of fractional AKNS hierarchy

    International Nuclear Information System (INIS)

    Wu, Guo-cheng; Zhang, Sheng

    2011-01-01

    In this Letter, a generalized Tu formula is firstly presented to construct Hamiltonian structures of fractional soliton equations. The obtained results can be reduced to the classical Hamiltonian hierarchy of AKNS in ordinary calculus. -- Highlights: → A generalized Tu formula is first established based on the fractional variational theory for non-differentiable functions. → Hamiltonian structures of fractional AKNS hierarchy are obtained. → The classical AKNS hierarchy is just a special case of the fractional hierarchy.

  7. A generalized Tu formula and Hamiltonian structures of fractional AKNS hierarchy

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Guo-cheng, E-mail: wuguocheng2002@yahoo.com.cn [Key Laboratory of Numerical Simulation of Sichuan Province, Neijiang, Sichuan 641112 (China); College of Mathematics and Information Science, Neijiang Normal University, Neijiang, Sichuan 641112 (China); Zhang, Sheng, E-mail: zhshaeng@yahoo.com.cn [School of Mathematical Sciences, Dalian University of Technology, Dalian 116024 (China)

    2011-10-03

    In this Letter, a generalized Tu formula is firstly presented to construct Hamiltonian structures of fractional soliton equations. The obtained results can be reduced to the classical Hamiltonian hierarchy of AKNS in ordinary calculus. -- Highlights: → A generalized Tu formula is first established based on the fractional variational theory for non-differentiable functions. → Hamiltonian structures of fractional AKNS hierarchy are obtained. → The classical AKNS hierarchy is just a special case of the fractional hierarchy.

  8. Transportvaneundersøgelsen - Variabeldeklaration : TU 2006-11, version 2

    DEFF Research Database (Denmark)

    Christiansen, Hjalmar

    Dette notat dokumenterer de leverede data i datasættet TU 2006-11 version 2, som omfatter data fra perioden maj 2006 til 30. April 2012. For den mest opdaterede dokumentation af nyeste TU-data henvises til vores hjemmeside. Nærværende notat følger såvidt muligt datasættet og opdateres ikke herefter....

  9. Transportvaneundersøgelsen - Variabeldeklaration : TU 2006-12, version 2

    DEFF Research Database (Denmark)

    Christiansen, Hjalmar; Skougaard, Britt Zoëga

    Dette notat dokumenterer de leverede data i datasættet TU 2006-12 version 2, som omfatter data fra perioden maj 2006 til 30. april 2012. For den mest opdaterede dokumentation af nyeste TU-data henvises til vores hjemmeside. Nærværende notat følger såvidt muligt datasættet og opdateres ikke herefter....

  10. The intensive DT neutron generator of TU Dresden

    Science.gov (United States)

    Klix, Axel; DÖring, Toralf; Domula, Alexander; Zuber, Kai

    2018-01-01

    TU Dresden operates an accelerator-based intensive DT neutron generator. Experimental activities comprise investigation into material activation and decay, neutron and photon transport in matter and R&D work on radiation detectors for harsh environments. The intense DT neutron generator is capable to produce a maximum of 1012 n/s. The neutron source is a solid-type water-cooled tritium target based on a titanium matrix on a copper carrier. The neutron yield at a typical deuteron beam current of 1 mA is of the order of 1011 n/s in 4Π. A pneumatic sample transport system is available for short-time irradiations and connected to wo high-purity germanium detector spectrometers for the measurement of induced activities. The overall design of the experimental hall with the neutron generator allows a flexible setup of experiments including the possibility of investigating larger structures and cooled samples or samples at high temperatures.

  11. The Nature of Man and Its Implications.

    Science.gov (United States)

    Pedrini, D. T.; Gregory, Lura N.

    The many problems presented by the nature of man and in studying man are the focus of this paper which attempts to place these problems in perspective in terms of the past and future. The enigma facing man, that man must study man, is related in an introduction. Freud's, Adler's, and Jung's developments in the study of the nature of man are…

  12. Play the Man!

    DEFF Research Database (Denmark)

    Edelberg, Peter

    . Men's bodies experienced a new form of interest in interwar Britain as physical training was becoming a general pursuit and sexual reformers and conservatives tried to come to terms with a post-Victorian society. The interwar period saw a strong tendency away from the ideal of men and women......This book investigates ideas of men and masculinities in interwar Britain in three different areas: psychology, physical education and sex. Using a broad range of sources from different walks of life it explores how men and masculinities were constructed in different ways for different purposes...... as opposites towards a heterosexual matrimonial ideal wherein men could try to establish a masculine identity. This tendency created new frontiers where homosexuals, 'perverts', 'misfits' and 'freaks' were seen as opposites of the 'real man' in the symbolic world of the early twentieth century....

  13. The 'poor man's laryngogram'

    International Nuclear Information System (INIS)

    Bartelt, D.

    1991-01-01

    This paper is reassessment of an old method improved by well-directed application of well-known maneuvers of laryngo-pharyngeal function. Although not as visually attractive as a dedicated laryngogram (now hardly ever requested), it does render similarly reliable diagnostic information, which, supported, as occasionally necessary, by conventional tomography, can even surpass that given by the older technique. Its main advantage lies in providing cheap, quick, noninvasive studies with minimal descomfort for the patient. Should further investigation be necessary, for analysis of deep extension, modern cross-sectional imaging methods (especially MR) far surpass even dedicated laryngography in diagnostic value and can be based adequately on 'poor mans's laryngography'. Ways in which this method may be optimised, especially those involving laryngopharyngeal function, are briefly presented - with emphasis on relevant practical aspects - as are normal and abnormal findings. (orig.) [de

  14. A neutron scattering study of the ternary complex EF-Tu.GTP-valyl-tRNAVal1A

    DEFF Research Database (Denmark)

    Österberg, R.; Elias, P.; Kjems, Jørgen

    1986-01-01

    The complex formation between elongation factor Tu (EF-Tu), GTP, and valyl-tRNAVal1A has been investigated in a hepes buffer of "pH" 7.4 and 0.2 M ionic strength using the small-angle neutron scattering method at concentrations of D2O where EF-Tu (42% D2O) and tRNA (71% D2O) are successively...

  15. Time-, Sex-, and Dose-Dependent Alterations of the Gut Microbiota by Consumption of Dietary Daikenchuto (TU-100

    Directory of Open Access Journals (Sweden)

    Jun Miyoshi

    2018-01-01

    Full Text Available Medications or dietary components can affect both the host and the host’s gut microbiota. Changes in the microbiota may influence medication efficacy and interactions. Daikenchuto (TU-100, a herbal medication, comprised of ginger, ginseng, and Japanese pepper, is widely used in Japanese traditional Kampo medicine for intestinal motility and postoperative paralytic ileus. We previously showed in mice that consumption of TU-100 for 4 weeks changed the gut microbiota and increased bioavailability of bacterial ginsenoside metabolites. Since TU-100 is prescribed in humans for months to years, we examined the time- and sex-dependent effects of TU-100 on mouse gut microbiota. Oral administration of 1.5% TU-100 for 24 weeks caused more pronounced changes in gut microbiota in female than in male mice. Changes in both sexes largely reverted to baseline upon TU-100 withdrawal. Effects were time and dose dependent. The microbial profiles reverted to baseline within 4 weeks after withdrawal of 0.75% TU-100 but were sustained after withdrawal of 3% TU-100. In summary, dietary TU-100 changed mouse microbiota in a time-, sex-, and dose-dependent manner. These findings may be taken into consideration when determining optimizing dose for conditions of human health and disease with the consideration of differences in composition and response of the human intestinal microbiota.

  16. Rich Man, Poor Man: Developmental Differences in Attributions and Perceptions

    Science.gov (United States)

    Sigelman, Carol K.

    2012-01-01

    In an examination guided by cognitive developmental and attribution theory of how explanations of wealth and poverty and perceptions of rich and poor people change with age and are interrelated, 6-, 10-, and 14-year-olds (N = 88) were asked for their causal attributions and trait judgments concerning a rich man and a poor man. First graders, like…

  17. Man Machine Systems in Education.

    Science.gov (United States)

    Sall, Malkit S.

    This review of the research literature on the interaction between humans and computers discusses how man machine systems can be utilized effectively in the learning-teaching process, especially in secondary education. Beginning with a definition of man machine systems and comments on the poor quality of much of the computer-based learning material…

  18. REMO poor man's reanalysis

    Science.gov (United States)

    Ries, H.; Moseley, C.; Haensler, A.

    2012-04-01

    Reanalyses depict the state of the atmosphere as a best fit in space and time of many atmospheric observations in a physically consistent way. By essentially solving the data assimilation problem in a very accurate manner, reanalysis results can be used as reference for model evaluation procedures and as forcing data sets for different model applications. However, the spatial resolution of the most common and accepted reanalysis data sets (e.g. JRA25, ERA-Interim) ranges from approximately 124 km to 80 km. This resolution is too coarse to simulate certain small scale processes often associated with extreme events. In addition, many models need higher resolved forcing data ( e.g. land-surface models, tools for identifying and assessing hydrological extremes). Therefore we downscaled the ERA-Interim reanalysis over the EURO-CORDEX-Domain for the time period 1989 to 2008 to a horizontal resolution of approximately 12 km. The downscaling is performed by nudging REMO-simulations to lower and lateral boundary conditions of the reanalysis, and by re-initializing the model every 24 hours ("REMO in forecast mode"). In this study the three following questions will be addressed: 1.) Does the REMO poor man's reanalysis meet the needs (accuracy, extreme value distribution) in validation and forcing? 2.) What lessons can be learned about the model used for downscaling? As REMO is used as a pure downscaling procedure, any systematic deviations from ERA-Interim result from poor process modelling but not from predictability limitations. 3.) How much small scale information generated by the downscaling model is lost with frequent initializations? A comparison to a simulation that is performed in climate mode will be presented.

  19. The intensive DT neutron generator of TU Dresden

    Directory of Open Access Journals (Sweden)

    Klix Axel

    2018-01-01

    Full Text Available TU Dresden operates an accelerator-based intensive DT neutron generator. Experimental activities comprise investigation into material activation and decay, neutron and photon transport in matter and R&D work on radiation detectors for harsh environments. The intense DT neutron generator is capable to produce a maximum of 1012 n/s. The neutron source is a solid-type water-cooled tritium target based on a titanium matrix on a copper carrier. The neutron yield at a typical deuteron beam current of 1 mA is of the order of 1011 n/s in 4Π. A pneumatic sample transport system is available for short-time irradiations and connected to wo high-purity germanium detector spectrometers for the measurement of induced activities. The overall design of the experimental hall with the neutron generator allows a flexible setup of experiments including the possibility of investigating larger structures and cooled samples or samples at high temperatures.

  20. Bacterial translation elongation factor EF-Tu interacts and colocalizes with actin-like MreB protein.

    Science.gov (United States)

    Defeu Soufo, Hervé Joël; Reimold, Christian; Linne, Uwe; Knust, Tobias; Gescher, Johannes; Graumann, Peter L

    2010-02-16

    We show that translation initiation factor EF-Tu plays a second important role in cell shape maintenance in the bacterium Bacillus subtilis. EF-Tu localizes in a helical pattern underneath the cell membrane and colocalizes with MreB, an actin-like cytoskeletal element setting up rod cell shape. The localization of MreB and of EF-Tu is interdependent, but in contrast to the dynamic MreB filaments, EF-Tu structures are more static and may serve as tracks for MreB filaments. In agreement with this idea, EF-Tu and MreB interact in vivo and in vitro. Lowering of the EF-Tu levels had a minor effect on translation but a strong effect on cell shape and on the localization of MreB, and blocking of the function of EF-Tu in translation did not interfere with the localization of MreB, showing that, directly or indirectly, EF-Tu affects the cytoskeletal MreB structure and thus serves two important functions in a bacterium.

  1. The YvfTU Two-component System is involved in plcR expression in Bacillus cereus

    Directory of Open Access Journals (Sweden)

    Nguyen-the Christophe

    2008-10-01

    Full Text Available Abstract Background Most extracellular virulence factors produced by Bacillus cereus are regulated by the pleiotropic transcriptional activator PlcR. Among strains belonging to the B. cereus group, the plcR gene is always located in the vicinity of genes encoding the YvfTU two-component system. The putative role of YvfTU in the expression of the PlcR regulon was therefore investigated. Results Expression of the plcR gene was monitored using a transcriptional fusion with a lacZ reporter gene in a yvfTU mutant and in its B. cereus ATCC 14579 parental strain. Two hours after the onset of the stationary phase, a stage at which the PlcR regulon is highly expressed, the plcR expression in the yvfTU mutant was only 50% of that of its parental strain. In addition to the reduced plcR expression in the yvfTU mutant, a few members of the PlcR regulon showed a differential expression, as revealed by transcriptomic and proteomic analyses. The virulence of the yvfTU mutant in a Galleria mellonella insect model was slightly lower than that of the parental strain. Conclusion The YvfTU two-component system is not required for the expression of most of the virulence factors belonging to the PlcR regulon. However, YvfTU is involved in expression of plcR, a major regulator of virulence in B. cereus.

  2. "Det man hører, er man selv"

    DEFF Research Database (Denmark)

    Bonde, Lars Ole

    2015-01-01

    ”Det man hører, er man selv” er Danmarks Radios P3s yderst velkendte slogan. Det dukkede op i begyndelsen af (20)00erne som opfindsom og populær afspejling af en moderne forståelse af den rolle musik og medieforbrug spiller for den voksne dansker. Denne artikel handler ikke om P3 som musikkanal...

  3. Japanese reference man 1988, 3

    International Nuclear Information System (INIS)

    Tanaka, Gi-ichiro

    1988-01-01

    Quantitative description of physical properties and other characteristics of the human body is one of the basic data for estimating dose equivalent and calculating Annual Limit on Intake of radionuclides. The exact mass weight of organs and tissues are measured from about 1000 autopsy cases of normal Japanese adults and physical properties are obtained from recent Japanese Government publications. Japanese (Asian) Reference Man is completed by establishing the Normal Japanese, harmonizing with Caucasian Reference Man and coinciding with the ICRP Reference Man Task Group members concept. (author)

  4. Dose-to-man studies

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    Dose-to-Man Studies focused on developing computer data handling and computer modules which permit easy, rapid assessment of the dose to southeastern United States populations from routine or accidental releases of radionuclides to atmospheric and stream systems

  5. Harmonization of sound insulation descriptors and classification schemes in Europe: COST Action TU0901

    DEFF Research Database (Denmark)

    Rasmussen, Birgit

    -in-Chief. Handbook of noise and vibration control, USA: Wiley and Son; 2007 [Ch. 114]. [4] COST Action TU0901 “Integrating and Harmonizing Sound Insulation Aspects in Sustainable Urban Housing Constructions”, 2009-2013, www.cost.eu/index.php?id=240&action_number=tu0901 (public information at COST website) or http...... insulation requirements seems unrealistic. However, by preparing a harmonized European classification scheme with a number of quality classes, member states could select a "harmonized" class fitting the national needs and conditions. A joint European Action, COST Action TU0901 "Integrating and Harmonizing...... on good workmanship. The paper will summarize the background, discuss the present situation in Europe and describe the joint efforts to reduce the diversity in Europe, thus supporting and initiating – where needed – improvement of sound insulation of new and existing dwellings in Europe to the benefit...

  6. Ar cinku aizvietotu hidroksilapatītu pētījumi

    OpenAIRE

    Komarovska, Laura

    2013-01-01

    Darbā apkopota informācija par hidroksilapatītu īpašībām, to sintēzes iespējām un izmantošanu. Apkopota informācija arī par izmantotajām darba un analīzes metodēm. Eksperimentālajā daļā veikta ar cinku, cēriju un cinku - cēriju aizvietotu hidroksilapatītu sintēze, izmantojot hidrotermisko metodi, kā sākotnējo izejvielu izmantojot amorfas vai kristāliskas fāzes hidroksilapatītu. Iegūtie pulveri raksturoti izmantojot pulvera rentgendifraktometriju un Furjē transformācijas infrasarkano spektrosk...

  7. Mapping Escherichia coli elongation factor Tu residues involved in binding of aminoacyl-tRNA

    DEFF Research Database (Denmark)

    Wiborg, Ove; Andersen, C; Knudsen, Charlotte Rohde

    1996-01-01

    Two residues of Escherichia coli elongation factor Tu involved in binding of aminoacyl-tRNA were identified and subjected to mutational analysis. Lys-89 and Asn-90 were each replaced by either Ala or Glu. The four single mutants were denoted K89A, K89E, N90A, and N90E, respectively. The mutants...... were characterized with respect to thermal and chemical stability, GTPase activity, tRNA affinity, and activity in an in vitro translation assay. Most conspicuously tRNA affinities were reduced for all mutants. The results verify our structural analysis of elongation factor Tu in complex with aminoacyl....... Their functional roles are discussed in relation to the structure of elongation factor Tu in complex with aminoacyl-tRNA. Udgivelsesdato: 1996-Aug-23...

  8. Towards an understanding of structure-function relationships of elongation factor Tu

    DEFF Research Database (Denmark)

    Wiborg, O; Andersen, C; Knudsen, Charlotte Rohde

    1994-01-01

    In light of the recently determined structure of elongation factor Tu, and taking into account chemical studies mapping functional sites, a number of residues have been selected for site-directed mutagenesis studies. Gly94, Gly126, His66, His118, Lys89 and Asp90 have each been point-mutated. Prel......In light of the recently determined structure of elongation factor Tu, and taking into account chemical studies mapping functional sites, a number of residues have been selected for site-directed mutagenesis studies. Gly94, Gly126, His66, His118, Lys89 and Asp90 have each been point...

  9. 46 CFR 151.45-3 - Manning.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Manning. 151.45-3 Section 151.45-3 Shipping COAST GUARD... HAZARDOUS MATERIAL CARGOES Operations § 151.45-3 Manning. Except as provided for in this section, barges need not be manned unless in the judgment of the Officer in Charge, Marine Inspection, such manning is...

  10. The Black Man in American Society.

    Science.gov (United States)

    Framingham Public Schools, MA.

    GRADE OR AGES: Junior high school. SUBJECT MATTER: The black man in American society. ORGANIZATION AND PHYSICAL APPEARANCE: There are four major parts each with an overview. The four parts concern a) the African heritage of the black man, b) the American exploitation of the black man, c) the black man's contribution to American society, d) the…

  11. An efficient algorithm for nucleolus and prekernel computation in some classes of TU-games

    NARCIS (Netherlands)

    Faigle, U.; Kern, Walter; Kuipers, J.

    1998-01-01

    We consider classes of TU-games. We show that we can efficiently compute an allocation in the intersection of the prekernel and the least core of the game if we can efficiently compute the minimum excess for any given allocation. In the case where the prekernel of the game contains exactly one core

  12. Darboux transformation and soliton solutions for the Boiti-Pempinelli-Tu (BPT) hierarchy

    International Nuclear Information System (INIS)

    Wang Jiong

    2005-01-01

    Starting from a spectral problem, we derive the well-known Boiti-Pempinelli-Tu (BPT) hierarchy. An explicit and universal Darboux transformation for the whole hierarchy is constructed. The soliton solutions for the BPT hierarchy are obtained by applying the Darboux transformation

  13. Comparison of Plasma Tu-M2-PK and CA19-9 in Pancreatic Cancer

    DEFF Research Database (Denmark)

    Joergensen, Maiken Thyregod; Heegaard, Niels H H; Schaffalitzky de Muckadell, Ove B

    2009-01-01

    because of suspicion of pancreatic cancer. Of these, 51 patients had their conditions diagnosed as PDAC, whereas this diagnosis was ruled out in 52 after 12 months of follow-up. The performance of Tu-M2-PK was compared with that of CA19-9 using cutoff values 15 and 37 U/mL, respectively. RESULTS...

  14. The Fic protein Doc uses an inverted substrate to phosphorylate and inactivate EF-Tu.

    Science.gov (United States)

    Castro-Roa, Daniel; Garcia-Pino, Abel; De Gieter, Steven; van Nuland, Nico A J; Loris, Remy; Zenkin, Nikolay

    2013-12-01

    Fic proteins are ubiquitous in all of the domains of life and have critical roles in multiple cellular processes through AMPylation of (transfer of AMP to) target proteins. Doc from the doc-phd toxin-antitoxin module is a member of the Fic family and inhibits bacterial translation by an unknown mechanism. Here we show that, in contrast to having AMPylating activity, Doc is a new type of kinase that inhibits bacterial translation by phosphorylating the conserved threonine (Thr382) of the translation elongation factor EF-Tu, rendering EF-Tu unable to bind aminoacylated tRNAs. We provide evidence that EF-Tu phosphorylation diverged from AMPylation by antiparallel binding of the NTP relative to the catalytic residues of the conserved Fic catalytic core of Doc. The results bring insights into the mechanism and role of phosphorylation of EF-Tu in bacterial physiology as well as represent an example of the catalytic plasticity of enzymes and a mechanism for the evolution of new enzymatic activities.

  15. Všechno už tu bylo. Jenom trochu menší.

    Czech Academy of Sciences Publication Activity Database

    Mikuláš, Radek

    2016-01-01

    Roč. 95, č. 3 (2016), s. 154-157 ISSN 0042-4544 Institutional support: RVO:67985831 Keywords : geology * geological history of the Earth * historical geology * geological eras * Anthropocene * paleontology * ichnology * fossils * trace fossils * fossil animals * sediments Subject RIV: DB - Geology ; Mineralogy http://casopis.vesmir.cz/clanek/vsechno-uz-tu-bylo

  16. CWI and TU Delft at TREC 2013: Contextual Suggestion, Federated Web Search, KBA, and Web Tracks

    NARCIS (Netherlands)

    A. Bellogín Kouki (Alejandro); G.G. Gebremeskel (Gebre); J. He (Jiyin); J.J.P. Lin (Jimmy); A. Said (Alan); T. Samar (Thaer); A.P. de Vries (Arjen); J.B.P. Vuurens (Jeroen)

    2014-01-01

    htmlabstractThis paper provides an overview of the work done at the Centrum Wiskunde & Informatica (CWI) and Delft University of Technology (TU Delft) for different tracks of TREC 2013. We participated in the Contextual Suggestion Track, the Federated Web Search Track, the Knowledge Base

  17. RESULTS OF AIRPLANE TU-204-300 OPERATED BY "VLADIVOSTOK AVIA" COMPANY FUEL FLOW MONITIRING

    Directory of Open Access Journals (Sweden)

    G. E. Maslennikova

    2014-01-01

    Full Text Available This article describes the results obtained from continuous monitoring of fuel flow on the airplanes Tu-204-300, operated by the aircompany "Vladivostok Avia". The reasons for the change in the cost of each copy of airplane and changes in fuel characteristics due to pilots manner of flying.

  18. Česká literatura a kultura za protektorátu

    Czech Academy of Sciences Publication Activity Database

    Piorecký, Karel

    2017-01-01

    Roč. 65, č. 3 (2017), s. 482-485 ISSN 0009-0468. [Česká literatura a kultura za protektorátu. Ostrava, 24.11.2016-25.11.2016] Institutional support: RVO:68378068 Keywords : Czech literature * 1938-1945 Subject RIV: AJ - Letters, Mass-media, Audiovision

  19. On the Potentials for Synergy Between COST Action TU1406 and the JCSS

    DEFF Research Database (Denmark)

    Nielsen, Michael Havbro Faber

    On of the main challenges of COST Action TU1406 is to identify, categorize and to the extent possible represent performance indicators of roadway bridges in a manner supporting decision making for their service life integrity management. This calls for an information consistent approach accounting...

  20. Economic man as model man: Ideal types, idealization and caricatures

    NARCIS (Netherlands)

    Morgan, M.S.

    2006-01-01

    Economics revolves around a central character: "economic man." As historians, we are all familiar with various episodes in the history of this character, and we appreciate his ever-changing aspect even while many of our colleagues in economics think the rational economic agent of neoclassical

  1. Establishment of Filipino standard man

    International Nuclear Information System (INIS)

    Natera, E.; San Jose, V.; Napenas, D.

    1984-01-01

    The initial data gathered on measurements of total body weight and weights of specific organs from autopsy cases of normal Filipinos are reported. Comparison of the above data with the Reference Man data of ICRP which was based primarily on Caucasians suggests some differences in the average weight and height of whole body and in the weights of some organs. Hence there appears to be a need for the establishment of Filipino standard man which can be used in the estimation of internal dose commitment of the Filipinos. (author)

  2. Establishment of Filipino standard man

    Energy Technology Data Exchange (ETDEWEB)

    Natera, E.; San Jose, V.; Napenas, D.

    The initial data gathered on measurements of total body weight and weights of specific organs from autopsy cases of normal Filipinos are reported. Comparison of the above data with the Reference Man data of ICRP which was based primarily on Caucasians suggests some differences in the average weight and height of whole body and in the weights of some organs. Hence there appears to be a need for the establishment of Filipino standard man which can be used in the estimation of internal dose commitment of the Filipinos.

  3. Mutational analysis of Escherichia coli elongation factor Tu in search of a role for the N-terminal region

    DEFF Research Database (Denmark)

    Mansilla, Francisco; Knudsen, Charlotte Rohde; Laurberg, M

    1998-01-01

    We have mutated lysine 2 and arginine 7 in elongation factor Tu from Escherichia coli separately either to alanine or glutamic acid. The aim of the work was to reveal the possible interactions between the conserved N-terminal part of the molecule, which is rich in basic residues and aminoacyl...... this activity. Furthermore, arginine 7 seems to play a role in regulating the binding of GTP. The three-dimensional structure of the ternary complex, EF-Tu:GTP:Phe-tRNAPhe, involving Thermus aquaticus EF-Tu and yeast Phe-tRNA(Phe), shows that Arg7 is in a position which permits salt bridge formation with Asp284...

  4. The rights of man and animal experimentation.

    OpenAIRE

    Martin, J

    1990-01-01

    Since emotions give contradictory signals about animal experimentation in medical science, man's relationship to animals must be based upon reason. Thomas Aquinas argues that man is essentially different from animals because man's intellectual processes show evidence of an abstract mechanism not possessed by animals. Man's rights arise in association with this essential difference. The consequence is that only man possesses true rights by Aquinas's definition; animals have them only by analog...

  5. Nonrandom γ-TuNA-dependent spatial pattern of microtubule nucleation at the Golgi.

    Science.gov (United States)

    Sanders, Anna A W M; Chang, Kevin; Zhu, Xiaodong; Thoppil, Roslin J; Holmes, William R; Kaverina, Irina

    2017-11-07

    Noncentrosomal microtubule (MT) nucleation at the Golgi generates MT network asymmetry in motile vertebrate cells. Investigating the Golgi-derived MT (GDMT) distribution, we find that MT asymmetry arises from nonrandom nucleation sites at the Golgi (hotspots). Using computational simulations, we propose two plausible mechanistic models of GDMT nucleation leading to this phenotype. In the "cooperativity" model, formation of a single GDMT promotes further nucleation at the same site. In the "heterogeneous Golgi" model, MT nucleation is dramatically up-regulated at discrete and sparse locations within the Golgi. While MT clustering in hotspots is equally well described by both models, simulating MT length distributions within the cooperativity model fits the data better. Investigating the molecular mechanism underlying hotspot formation, we have found that hotspots are significantly smaller than a Golgi subdomain positive for scaffolding protein AKAP450, which is thought to recruit GDMT nucleation factors. We have further probed potential roles of known GDMT-promoting molecules, including γ-TuRC-mediated nucleation activator (γ-TuNA) domain-containing proteins and MT stabilizer CLASPs. While both γ-TuNA inhibition and lack of CLASPs resulted in drastically decreased GDMT nucleation, computational modeling revealed that only γ-TuNA inhibition suppressed hotspot formation. We conclude that hotspots require γ-TuNA activity, which facilitates clustered GDMT nucleation at distinct Golgi sites. © 2017 Sanders et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  6. The Turkism Idea in Kızıl Tuğ Novel

    Directory of Open Access Journals (Sweden)

    Ahmet İhsan KAYA

    2016-06-01

    Full Text Available Kızıl Tuğ is the first and most important novel by Abdullah Ziya Kozanoğlu, who was a writer of history novels. The novel, published in 1927, was among the best seller until 1980s. Kızıl Tuğ, the important history adventure novels of the Turkish Literature, was also the first history novel of the Republican Period of Turkish Literature. It acted as a source for comic books newly entering the Turkish Literature and as a Pioneer for Yeşilçam movies narrating heroic figures in The Turkish history the novel influenced the following history novelists in this respect. In addition to its popularity among the youth and the children, this work of literature still has effects on contemporary intellectuals and politicians. Kızıl Tuğ narrates the Middle Asian Turkish history in the first quarter of 1200s. The author focuses on the importance of the Turkish Union while narrating the war between Genghis Khan and China. Kızıl Tuğ was written under the idea of nation-state, and it was fictionalized to express the sovereignty of The Turkish nation and the origins of The Turkish people. Kızıl Tuğ, which has an important place in Turkish culture and literature, is of great importance in Turkish Literature since it reflects A. Ziya Kozanoğlu’s perspective on Turkish nation and his concept of Turkism

  7. Man and the Pongolo floodplain

    CSIR Research Space (South Africa)

    Heeg, J

    1982-06-01

    Full Text Available This report comprises a synthesis of contributions to a workshop on Man and the Pongolo held at the University of Natal, Pietermaritzburg in February 1978. Studies on the ecology of the Pongolo floodplain, encompassing its fauna, flora and human...

  8. The Man Who Knew Infinity

    Indian Academy of Sciences (India)

    his work. Ramanujan did mathematics for its own sake, for the thrill that he got in seeing and discovering ... in those times led to a frantic search for a job to earn an income. .... mathematics, a man whose career seems full of paradoxes and ...

  9. Man...An Endangered Species?

    Science.gov (United States)

    Department of the Interior, Washington, DC.

    The general theme of this 1968 yearbook is that man is a threatened species, facing overpopulation and unbridled technology - both self induced. The presentation is broad, relating to many aspects of conservation and natural resources in the United States in a descriptive, non-technical style. The yearbook is divided into major topics: Land…

  10. The half-yellow man

    African Journals Online (AJOL)

    The half-yellow man. BJ Merwitza* and FJ Raala. aFaculty of Health Sciences, Carbohydrate and Lipid Metabolism Research Unit, University of the Witswaterand, Johannesburg, South Africa. *Corresponding author, emails: bmerwitz@hotmail.com, brad.merwitz@gmail.com. Keywords: diffuse normolipaemic planar ...

  11. Man and Machines: Three Criticisms.

    Science.gov (United States)

    Schneider, Edward F.

    As machines have become a more common part of daily life through the passage of time, the idea that the line separating man and machine is slowly fading has become more popular as well. This paper examines three critics of change through their most famous works. One of the most popular views of Mary Shelley's "Frankenstein" is that it is a…

  12. Man-Made Climatic Changes

    Science.gov (United States)

    Landsberg, Helmut E.

    1970-01-01

    Reviews environmental studies which show that national climatic fluctuations vary over a wide range. Solar radiation, earth temperatures, precipitation, atmospheric gases and suspended particulates are discussed in relation to urban and extraurban effects. Local weather modifications and attempts at climate control by man seem to have substantial…

  13. Man, Controller of the Universe

    Science.gov (United States)

    Olowin, R. P.

    2011-06-01

    The Man, Controller of the Universe painted by the renowned Mexican artist Diego Rivera in the gigantic mural of the Palace of Fine Arts in Mexico City is overlooked by a telescope. We acknowledge this instrument as the Plaskett Telescope at the Dominion Astrophysical Observatory in Victoria, Canada.

  14. Man-machine design integration

    Energy Technology Data Exchange (ETDEWEB)

    Carrera, J.P. [Westinghouse Electric Corp., Monroeville, PA (United States). Nuclear Technology Div.; Haentjens, J. [Westinghouse Electric Corp., Brussels (Belgium). Nuclear Technology Div.

    1995-12-31

    The presentation overviews the bases for Man-Machine Interface (MMI) designs that are part of three other presentations during the same conference: Advanced Alarm Management System, Functional Displays and System for Emergency Procedure Execution Monitoring. The MMD group history, team and goals are summarized to give some context to the core of the MMD philosophy and integration. (10 refs., 5 figs.).

  15. Function and structure in phage Qbeta RNA replicase. Association of EF-Tu-Ts with the other enzyme subunits

    DEFF Research Database (Denmark)

    Blumenthal, T; Young, R A; Brown, S

    1976-01-01

    alters its quaternary structure: the EF-Tu-Ts cannot be covalently attached to the other enzyme subunits with bifunctional cross-linking reagents in the presence of RNA. This conformational change is not influenced by ionic strength. The addition of Qbeta RNA to the enzyme, does not result in the release...... for one another increases with increasing ionic strength. The enzyme is capable of initiation of RNA synthesis with synthetic templates only when in the low ionic strength conformation. Elongation of initiated polynucleotide chains is not affectedby ionic strength. Addition of Qbeta RNA to the enzyme also...... of EF-Tu-Ts from the other enzyme subunits: whereas free EF-Tu-Ts binds GDP independently of salt concentration, this binding by Qbeta replicase is sensitive to high ionic strength and remains so in the presence of Qbeta RNA. Furthermore, RNA does not allow the release of EF-Ts from EF-Tu by GTP...

  16. Duplication of Drosophila melanogaster mitochondrial EF-Tu: pre-adaptation to T-arm truncation and exclusion of bulky aminoacyl residues.

    Science.gov (United States)

    Sato, Aya; Suematsu, Takuma; Aihara, Koh-Ki; Kita, Kiyoshi; Suzuki, Tsutomu; Watanabe, Kimitsuna; Ohtsuki, Takashi; Watanabe, Yoh-Ichi

    2017-03-07

    Translation elongation factor Tu (EF-Tu) delivers aminoacyl-tRNA (aa-tRNA) to ribosomes in protein synthesis. EF-Tu generally recognizes aminoacyl moieties and acceptor- and T-stems of aa-tRNAs. However, nematode mitochondrial (mt) tRNAs frequently lack all or part of the T-arm that is recognized by canonical EF-Tu. We previously reported that two distinct EF-Tu species, EF-Tu1 and EF-Tu2, respectively, recognize mt tRNAs lacking T-arms and D-arms in the mitochondria of the chromadorean nematode Caenorhabditis elegans C. elegans EF-Tu2 specifically recognizes the seryl moiety of serylated D-armless tRNAs. Mitochondria of the enoplean nematode Trichinella possess three structural types of tRNAs: T-armless tRNAs, D-armless tRNAs, and cloverleaf tRNAs with a short T-arm. Trichinella mt EF-Tu1 binds to all three types and EF-Tu2 binds only to D-armless Ser-tRNAs, showing an evolutionary intermediate state from canonical EF-Tu to chromadorean nematode (e.g. C. elegans ) EF-Tu species. We report here that two EF-Tu species also participate in Drosophila melanogaster mitochondria. Both D. melanogaster EF-Tu1 and EF-Tu2 bound to cloverleaf and D-armless tRNAs. D. melanogaster EF-Tu1 has the ability to recognize T-armless tRNAs that do not evidently exist in D. melanogaster mitochondria, but do exist in related arthropod species. In addition, D. melanogaster EF-Tu2 preferentially bound to aa-tRNAs carrying small amino acids, but not to aa-tRNAs carrying bulky amino acids. These results suggest that the Drosophila mt translation system could be another intermediate state between the canonical and nematode mitochondria-type translation systems. © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society.

  17. Translation elongation factor EF-Tu modulates filament formation of actin-like MreB protein in vitro.

    Science.gov (United States)

    Defeu Soufo, Hervé Joël; Reimold, Christian; Breddermann, Hannes; Mannherz, Hans G; Graumann, Peter L

    2015-04-24

    EF-Tu has been shown to interact with actin-like protein MreB and to affect its localization in Escherichia coli and in Bacillus subtilis cells. We have purified YFP-MreB in an active form, which forms filaments on glass slides in vitro and was active in dynamic light-scattering assays, polymerizing in milliseconds after addition of magnesium. Purified EF-Tu enhanced the amount of MreB filaments, as seen by sedimentation assays, the speed of filament formation and the length of MreB filaments in vitro. EF-Tu had the strongest impact on MreB filaments in a 1:1 ratio, and EF-Tu co-sedimented with MreB filaments, revealing a stoichiometric interaction between both proteins. This was supported by cross-linking assays where 1:1 species were well detectable. When expressed in E. coli cells, B. subtilis MreB formed filaments and induced the formation of co-localizing B. subtilis EF-Tu structures, indicating that MreB can direct the positioning of EF-Tu structures in a heterologous cell system. Fluorescence recovery after photobleaching analysis showed that MreB filaments have a higher turnover in B. subtilis cells than in E. coli cells, indicating different filament kinetics in homologous or heterologous cell systems. The data show that MreB can direct the localization of EF-Tu in vivo, which in turn positively affects the formation and dynamics of MreB filaments. Thus, EF-Tu is a modulator of the activity of a bacterial actin-like protein. Copyright © 2015. Published by Elsevier Ltd.

  18. Comparative measurement of sup(99m)Tc-thyroid-uptake (TcTU) using two different methods of data analysis

    International Nuclear Information System (INIS)

    Hotze, L.A.; Schmitz, R.

    1982-01-01

    A new program for automatic measurement of TcTU was developed and compared with a standard interactive method of data analysis. The new program fullfils the requirements for correct calculation of TcTU. The advantages are: reduced working load for the technician and a diminished frequency of erroneous results by improving automatisation of data handling and procedure of activity measurement as well as detailed informative dialogue with the computer without any need for special knowledge of data processing. (orig.) [de

  19. The DIAN-TU Next Generation Alzheimer’s prevention trial: adaptive design and disease progression model

    Science.gov (United States)

    Bateman, Randall J.; Benzinger, Tammie L.; Berry, Scott; Clifford, David B.; Duggan, Cynthia; Fagan, Anne M.; Fanning, Kathleen; Farlow, Martin R.; Hassenstab, Jason; McDade, Eric M.; Mills, Susan; Paumier, Katrina; Quintana, Melanie; Salloway, Stephen P.; Santacruz, Anna; Schneider, Lon S.; Wang, Guoqiao; Xiong, Chengjie

    2016-01-01

    INTRODUCTION The Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) trial is an adaptive platform trial testing multiple drugs to slow or prevent the progression of Alzheimer’s disease in autosomal dominant Alzheimer’s disease (ADAD) families. With completion of enrollment of the first two drug arms, the DIAN-TU now plans to add new drugs to the platform, designated as the Next Generation Prevention Trial (NexGen). METHODS In collaboration with ADAD families, philanthropic organizations, academic leaders, the DIAN-TU Pharma Consortium, the NIH, and regulatory colleagues, the DIAN-TU developed innovative clinical study designs for the DIAN-TU NexGen trial. RESULTS Our expanded trials toolbox consists of a Disease Progression Model for ADAD, primary endpoint DIAN-TU cognitive performance composite, biomarker development, self-administered cognitive assessments, adaptive dose adjustments, and blinded data collection through the last participant completion. CONCLUSION These steps represent elements to improve efficacy of the adaptive platform trial and a continued effort to optimize prevention and treatment trials in ADAD. PMID:27583651

  20. Teleoperators: Man's Machine Partners

    Energy Technology Data Exchange (ETDEWEB)

    Corliss, William R.

    1972-01-01

    This booklet is about teleoperators, a class of machines that augment man rather than replace him. Teleoperators have the ability to add to man's strength, his reach, and his ability to work in hostile environments.

  1. Töötu laevamehhaanik õppis seitsme kuuga kokaks / Agne Narusk

    Index Scriptorium Estoniae

    Narusk, Agne, 1971-

    2004-01-01

    Töötu Jevgeni Solovjov õppis OÜ-s Isabella kokaks, ettevõte on üks 54 koolitajast, kellelt Tallinna tööhõiveamet teenust ostab. 2004. aastaks oli Tallinna tööhõiveametil tööotsijate koolitamiseks 7 mln krooni, millest jätkus pooleks aastaks. Lisa: Tööandjad saavad küsitluslehed

  2. Bacterial elongation factors EF-Tu, their mutants, chimeric forms, and domains: isolation and purification

    Czech Academy of Sciences Publication Activity Database

    Jonák, Jiří

    2007-01-01

    Roč. 849, 1-2 (2007), s. 141-153 ISSN 1570-0232 R&D Projects: GA AV ČR IAA5052206; GA AV ČR KJB500520503; GA MŠk 2B06065 Institutional research plan: CEZ:AV0Z50520514 Keywords : bacterial elongation factors EF-Tu, , G-domain * recombinant EF-Tus * preparation Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 2.935, year: 2007

  3. 77 FR 23806 - Manning Rail, Inc.-Acquisition and Operation Exemption-Manning Grain Company

    Science.gov (United States)

    2012-04-20

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35607] Manning Rail, Inc.--Acquisition and Operation Exemption--Manning Grain Company Manning Rail, Inc. (MRI), a noncarrier, has filed a verified notice of exemption \\1\\ under 49 CFR 1150.31 to acquire from Manning Grain Company (MGC) and...

  4. Kinetic study of the substitution of [Tc(tu)6]3+ by polyaminocarboxylic acids

    International Nuclear Information System (INIS)

    Torres, J.; Gonalez, R.; Kremer, C.; Kremer, E.; Leon, A.

    1997-01-01

    Substitution route has been traditionally proposed for the synthesis of new Tc complexes. In particular, Tc(III) coordination compounds can be successfully prepared by substitution on [Tc(tu) 6 ] 3+ (tu = thiourea). In this substitution reaction, TcO 2 is a side product that should be minimized. The success of these synthetic procedures is based on controlling the reaction conditions in order that pure substitution could be faster enough compared to decomposition. In this work, the substitution of [Tc(tu) 6 ] 3+ by polycarboxylic acids (ethylenediaminetetraacetate (edta), diethylenetriaminepentaacetate (dtpa), N-tris(2-amino-ethyl)amin N', N', N '' , N '' , N ''' , N ''' -hexaacetate (ttaha) and 3-bromo-2,4,6-trimethylacetanilideiminodiacetate (mebrofenin)) is kinetically studied in order to obtain the best conditions for preparing Tc(III) complexes. As a general conclusion, substitution constants are strongly dependent on the pH. k obs values fall in the range 0.1-13 x 10 -2 M -1 s -1 , depending on the pH value and the temperature. No strong differences are found with different incoming ligands. For the four ligands (L), a straight line is obtained when plotting log k obs /([L m- ]) vs. pH. This is consistent with a rate constant k obs = {k 0 + Σk n [H + ] n /K n }[L m- ], where n represents the charge of the incoming ligand and m is the maximum value of n. (orig.)

  5. Arabidopsis EF-Tu receptor enhances bacterial disease resistance in transgenic wheat.

    Science.gov (United States)

    Schoonbeek, Henk-Jan; Wang, Hsi-Hua; Stefanato, Francesca L; Craze, Melanie; Bowden, Sarah; Wallington, Emma; Zipfel, Cyril; Ridout, Christopher J

    2015-04-01

    Perception of pathogen (or microbe)-associated molecular patterns (PAMPs/MAMPs) by pattern recognition receptors (PRRs) is a key component of plant innate immunity. The Arabidopsis PRR EF-Tu receptor (EFR) recognizes the bacterial PAMP elongation factor Tu (EF-Tu) and its derived peptide elf18. Previous work revealed that transgenic expression of AtEFR in Solanaceae confers elf18 responsiveness and broad-spectrum bacterial disease resistance. In this study, we developed a set of bioassays to study the activation of PAMP-triggered immunity (PTI) in wheat. We generated transgenic wheat (Triticum aestivum) plants expressing AtEFR driven by the constitutive rice actin promoter and tested their response to elf18. We show that transgenic expression of AtEFR in wheat confers recognition of elf18, as measured by the induction of immune marker genes and callose deposition. When challenged with the cereal bacterial pathogen Pseudomonas syringae pv. oryzae, transgenic EFR wheat lines had reduced lesion size and bacterial multiplication. These results demonstrate that AtEFR can be transferred successfully from dicot to monocot species, further revealing that immune signalling pathways are conserved across these distant phyla. As novel PRRs are identified, their transfer between plant families represents a useful strategy for enhancing resistance to pathogens in crops. © 2015 The Authors. New Phytologist © 2015 New Phytologist Trust.

  6. Kant and the practical man

    DEFF Research Database (Denmark)

    Nielsen, Carsten Fogh

    2017-01-01

    The Appendix to Kant’s Toward perpetual peace is commonly viewed as an explication of the systematic relations between political practice and normative political theory. This paper provides an alternative interpretation to Kant’s main aim in the Apendix which is to provide an argument against...... that Kant’s argument against the practical man is based on a proto-phenomenological analysis of moral experience. The practical man’s attempt to describe political practice in purely non-normative terms is, Kant believes, necessarily self-undermining because it denies one of the most basic aspects of human...

  7. Man - Environment - Knowledge. 2. ed.

    International Nuclear Information System (INIS)

    Fritsch, B.

    1991-01-01

    The book brings together certain facts which were collated and processed on the subject of ''Man-Environment-Knowledge'' within the scope of a tutorial function of the same name organised and held by the ''ETH'' (the Swiss Federal Institute of Technology in Zurich). Starting off from certain important fundamental facts which reproduce the current state of our planet in the form of data, it goes on to illustrate those interconnections and processes that are important for the understanding of the world in which we live. figs., tabs., [800 refs.

  8. Effects of radiation on man

    International Nuclear Information System (INIS)

    Saunders, P.A.H.

    1981-01-01

    The available evidence on the effects of radiation on man and the predictions that have been made of possible low level effects are reviewed. Data from United Nations Scientific Committee of the Effects of Atomic Radiation (UNSCEAR) and the committee on the Biological Effects of Ionising Radiation (BEIR) is used to illustrate the acute, delayed and hereditary effects of high dose levels. The effects of low dose levels are discussed on the assumption that both somatic and hereditary effects can be predicted on the basis of linear extrapolation from high dose effects. (U.K.)

  9. Chinese Manned Space Utility Project

    Science.gov (United States)

    Gu, Y.

    Since 1992 China has been carrying out a conspicuous manned space mission A utility project has been defined and created during the same period The Utility Project of the Chinese Manned Space Mission involves wide science areas such as earth observation life science micro-gravity fluid physics and material science astronomy space environment etc In the earth observation area it is focused on the changes of global environments and relevant exploration technologies A Middle Revolution Image Spectrometer and a Multi-model Micro-wave Remote Sensor have been developed The detectors for cirrostratus distribution solar constant earth emission budget earth-atmosphere ultra-violet spectrum and flux have been manufactured and tested All of above equipment was engaged in orbital experiments on-board the Shenzhou series spacecrafts Space life science biotechnologies and micro-gravity science were much concerned with the project A series of experiments has been made both in ground laboratories and spacecraft capsules The environmental effect in different biological bodies in space protein crystallization electrical cell-fusion animal cells cultural research on separation by using free-low electrophoresis a liquid drop Marangoni migration experiment under micro-gravity as well as a set of crystal growth and metal processing was successfully operated in space The Gamma-ray burst and high-energy emission from solar flares have been explored A set of particle detectors and a mass spectrometer measured

  10. Man-machine interactions 3

    CERN Document Server

    Czachórski, Tadeusz; Kozielski, Stanisław

    2014-01-01

    Man-Machine Interaction is an interdisciplinary field of research that covers many aspects of science focused on a human and machine in conjunction.  Basic goal of the study is to improve and invent new ways of communication between users and computers, and many different subjects are involved to reach the long-term research objective of an intuitive, natural and multimodal way of interaction with machines.  The rapid evolution of the methods by which humans interact with computers is observed nowadays and new approaches allow using computing technologies to support people on the daily basis, making computers more usable and receptive to the user's needs.   This monograph is the third edition in the series and presents important ideas, current trends and innovations in  the man-machine interactions area.  The aim of this book is to introduce not only hardware and software interfacing concepts, but also to give insights into the related theoretical background. Reader is provided with a compilation of high...

  11. [The man on the portrait].

    Science.gov (United States)

    Bergstrand, A

    1996-01-01

    Marie Curie was awarded the Nobel Prize in chemistry 1911. During the preceding year a rumour had circulated in Stockholm that she had had an affaire with one of her assistants. She received a letter, in which she was told that there had been strong opposition to her election not on scientific but moral grounds, and that she should not go to Stockholm, because nobody could forsee what reactions her appearance at the prize ceremony could evoke. Emil Kleen, a man of violent temper and radical opinions, reacted strongly to these rumours. He wrote a paper, with a violent attack on Gustaf Retzius, previous professor of Histology at Karolinska Institutet. Rightly or wrongly he suspected him to be the author of the infamous letter. Retzius is described as a dilletant in scientific matters, as a "sexual hyena" and a garroulus old man. This portrait of Retzius is of course most unfair, but the portrait of Emil Kleen by the famous swedish artist Bruno Liljefors is a masterpiece and one of the most valuable of the Swedish Medical Association.

  12. Simultaneous Binding of Multiple EF-Tu Copies to Translating Ribosomes in Live Escherichia coli.

    Science.gov (United States)

    Mustafi, Mainak; Weisshaar, James C

    2018-01-16

    In bacteria, elongation factor Tu is a translational cofactor that forms ternary complexes with aminoacyl-tRNA (aa-tRNA) and GTP. Binding of a ternary complex to one of four flexible L7/L12 units on the ribosome tethers a charged tRNA in close proximity to the ribosomal A site. Two sequential tests for a match between the aa-tRNA anticodon and the current mRNA codon then follow. Because one elongation cycle can occur in as little as 50 ms and the vast majority of aa-tRNA copies are not cognate with the current mRNA codon, this testing must occur rapidly. We present a single-molecule localization and tracking study of fluorescently labeled EF-Tu in live Escherichia coli Imaging at 2 ms/frame distinguishes 60% slowly diffusing EF-Tu copies (assigned as transiently bound to translating ribosome) from 40% rapidly diffusing copies (assigned as a mixture of free ternary complexes and free EF-Tu). Combining these percentages with copy number estimates, we infer that the four L7/L12 sites are essentially saturated with ternary complexes in vivo. The results corroborate an earlier inference that all four sites can simultaneously tether ternary complexes near the A site, creating a high local concentration that may greatly enhance the rate of testing of aa-tRNAs. Our data and a combinatorial argument both suggest that the initial recognition test for a codon-anticodon match occurs in less than 1 to 2 ms per aa-tRNA copy. The results refute a recent study (A. Plochowietz, I. Farrell, Z. Smilansky, B. S. Cooperman, and A. N. Kapanidis, Nucleic Acids Res 45:926-937, 2016, https://doi.org/10.1093/nar/gkw787) of tRNA diffusion in E. coli that inferred that aa-tRNAs arrive at the ribosomal A site as bare monomers, not as ternary complexes. IMPORTANCE Ribosomes catalyze translation of the mRNA codon sequence into the corresponding sequence of amino acids within the nascent polypeptide chain. Polypeptide elongation can be as fast as 50 ms per added amino acid. Each amino acid

  13. The rights of man and animal experimentation.

    Science.gov (United States)

    Martin, J

    1990-01-01

    Since emotions give contradictory signals about animal experimentation in medical science, man's relationship to animals must be based upon reason. Thomas Aquinas argues that man is essentially different from animals because man's intellectual processes show evidence of an abstract mechanism not possessed by animals. Man's rights arise in association with this essential difference. The consequence is that only man possesses true rights by Aquinas's definition; animals have them only by analogy. However, cruelty to animals is illicit and they should be protected, principally not because they have rights, but because he who is cruel to animals is more likely to be cruel to his fellowman. If there is a need for animal experimentation in science for the good of man, this approach gives philosophical justification for experimentation, since man's well-being must come before that of animals because of his unique possession of rights. However, those experiments should be carried out in the kindest way possible, to promote kindness towards man. To see man as solely part of a biological continuum in competition for rights with those beings close to him biologically, detracts from man's dignity. PMID:2135948

  14. Enhancement of innate immune system in monocot rice by transferring the dicotyledonous elongation factor Tu receptor EFR

    Institute of Scientific and Technical Information of China (English)

    Fen Lu; Huiqin Wang; Shanzhi Wang; Wendi Jiang; Changlin Shan; Bin Li; Jun Yang; Shiyong Zhang; Wenxian Sun

    2015-01-01

    The elongation factor Tu (EF-Tu) receptor (EFR) in cruciferous plants specifical y recognizes the N-terminal acetylated elf18 region of bacterial EF-Tu and thereby activates plant immunity. It has been demonstrated that Arabidopsis EFR confers broad-spectrum bacterial resistance in the EFR transgenic solanaceous plants. Here, the transgenic rice plants (Oryza sativa L. ssp. japonica cv. Zhonghua 17) and cel cultures with constitutive expression of AtEFR were developed to investigate whether AtEFR senses EF-Tu and thus enhances bacterial resistance in the monocot plants. We demonstrated that the Xanthomonas oryzae-derived elf18 peptide induced oxidative burst and mitogen-activated protein kinase activa-tion in the AtEFR transgenic rice cel s and plants, respectively. Pathogenesis-related genes, such as OsPBZ1, were upregulated dramatical y in transgenic rice plant and cel lines in response to elf18 stimulation. Importantly, pretreatment with elf18 trig-gered strong resistance to X. oryzae pv. oryzae in the transgenic plants, which was largely dependent on the AtEFR expression level. These plants also exhibited enhanced resistance to rice bacterial brown stripe, but not to rice fungal blast. Col ectively, the results indicate that the rice plants with heterologous expression of AtEFR recognize bacterial EF-Tu and exhibit enhanced broad-spectrum bacterial disease resistance and that pattern recognition receptor-mediated immunity may be manipulated across the two plant classes, dicots and monocots.

  15. Tööotsija töötuks tunnistamise ning töötu abiraha määramise ja maksmise ajutise juhendi kinnitamise kohta

    Index Scriptorium Estoniae

    1991-01-01

    Kehtib 1. aprillist 1991. Lisatud ajutine juhend: töö vahendamine tööotsijale, töötule, töötu abiraha määramine ja maksmine Lisatud: töötu abiraha arvutamine. Muudatus: RT I 1992 nr. 27 art. 362

  16. Site-directed mutagenesis of Arg58 and Asp86 of elongation factor Tu from Escherichia coli: effects on the GTPase reaction and aminoacyl-tRNA binding

    DEFF Research Database (Denmark)

    Knudsen, Charlotte Rohde; Clark, Brian F. C.

    1996-01-01

    Elongation factor Tu from Escherichia coli was mutated separately at positions Asp86 and Arg58, in order to shed light both on the GTPase mechanism of elongation factor Tu and on the binding of aminoacyl-tRNA. In addition, the binding of guanine nucleotides was investigated by determination...

  17. Elongation factor Ts directly facilitates the formation and disassembly of the Escherichia coli elongation factor Tu·GTP·aminoacyl-tRNA ternary complex.

    Science.gov (United States)

    Burnett, Benjamin J; Altman, Roger B; Ferrao, Ryan; Alejo, Jose L; Kaur, Navdep; Kanji, Joshua; Blanchard, Scott C

    2013-05-10

    Aminoacyl-tRNA (aa-tRNA) enters the ribosome in a ternary complex with the G-protein elongation factor Tu (EF-Tu) and GTP. EF-Tu·GTP·aa-tRNA ternary complex formation and decay rates are accelerated in the presence of the nucleotide exchange factor elongation factor Ts (EF-Ts). EF-Ts directly facilitates the formation and disassociation of ternary complex. This system demonstrates a novel function of EF-Ts. Aminoacyl-tRNA enters the translating ribosome in a ternary complex with elongation factor Tu (EF-Tu) and GTP. Here, we describe bulk steady state and pre-steady state fluorescence methods that enabled us to quantitatively explore the kinetic features of Escherichia coli ternary complex formation and decay. The data obtained suggest that both processes are controlled by a nucleotide-dependent, rate-determining conformational change in EF-Tu. Unexpectedly, we found that this conformational change is accelerated by elongation factor Ts (EF-Ts), the guanosine nucleotide exchange factor for EF-Tu. Notably, EF-Ts attenuates the affinity of EF-Tu for GTP and destabilizes ternary complex in the presence of non-hydrolyzable GTP analogs. These results suggest that EF-Ts serves an unanticipated role in the cell of actively regulating the abundance and stability of ternary complex in a manner that contributes to rapid and faithful protein synthesis.

  18. Tesla man out of time

    CERN Document Server

    Cheney, Margaret

    1981-01-01

    Called a madman by some, a genius by others, and an enigma by nearly everyone, Nikola Tesla created astonishing, world-transforming devises that were virtually without theoretical precedent. Tesla not only discovered the rotating magnetic field, the basis of most alternating current machinery, but also introduced the fundamentals of robotry, computers, and missile science and helped pave the way for such technologies as satellites, microwaves, beam weapons, and nuclear fusion. Almost supernaturally gifted, Tesla was also unusually erratic, flamboyant, and neurotic. He was J. P. Morgan's client, counted Mark Twain as a friend, and considered Thomas Edison an enemy. But above all, he was the hero and mentor to many of the last century's most famous scientists. In a meticulously researched, engagingly written biography, Margaret Cheney presents the many different dimensions of this extraordinary man, capturing his human qualities and quirks as she chronicles a lifetime of discoveries that continue to alter our ...

  19. Deformation of Man Made Objects

    KAUST Repository

    Ibrahim, Mohamed

    2012-07-01

    We introduce a framework for 3D object deformation with primary focus on man-made objects. Our framework enables a user to deform a model while preserving its defining characteristics. Moreover, our framework enables a user to set constraints on a model to keep its most significant features intact after the deformation process. Our framework supports a semi-automatic constraint setting environment, where some constraints could be automatically set by the framework while others are left for the user to specify. Our framework has several advantages over some state of the art deformation techniques in that it enables a user to add new features to the deformed model while keeping its general look similar to the input model. In addition, our framework enables the rotation and extrusion of different parts of a model.

  20. Man's limitations. The Catholic view.

    Science.gov (United States)

    Bacani, T

    1993-10-27

    The Assistant Bishop of Manila, Philippines, comments on Pope John Paul II teachings and former Pope Paul VI's Humanae Vitae. The Roman Catholic Church over the past twenty five years has not accepted modern contraception. Lay Catholics are confused over the appropriate behavior regarding family planning, are ignorant of the Church's teachings, or have followed their conscience. Critics say that the teachings are obsolete and unheeded. Church officials respond that the Church is run by divine inspiration and not majority rule. The Church position is based on reason and on God himself, who prohibits man-made contraception. Paul VI revealed that the conjugal act was the link between unitive and procreative meanings, and man did not have the right to break the link on his own initiative. John Paul II reaffirms this position by stating that human beings do not have "absolute dominion over the conjugal act" and are not the final arbiters of the creation of life. Humans are servants of the creation of new life as collaborators and procreators. Humans act like Gods when they deprive the conjugal act of procreative meaning through contraceptive use. Natural family planning does not violate this divine prerogative. The Pope's teachings are verified. There is evidence of declines in conjugal infidelity, the lowering of moral standards, increased abortion, and the demise of demographic imperialism. The Church recognizes the problem of overpopulation, and the Catholic Bishops Conference of the Philippines acknowledges the responsibility of all sectors of society to solve the problem. Catholics in the Philippines are opposed to the Ramos' administration's aggressive birth control program. The opposition is due to the government's lack of provision of sufficient information about the side effects of modern contraceptives and the neglect of natural family planning, which is the only morally legitimate form of contraception sanctioned by Roman Catholics. Freedom of choice means

  1. Biosafety in manned space flight

    International Nuclear Information System (INIS)

    De Boever, P.

    2006-01-01

    The main goal of manned exploration is to achieve a prolonged stay in space, for example in an orbital station (such as the International Space Station (ISS)) or in planetary bases on the Moon and/or Mars. It goes without saying that such missions can only be realized when the astronaut's health and well-being is secured. In this respect, the characterization of the microbiological contamination on board spacecraft and orbital stations and the influence of cosmic radiation and microgravity are of paramount importance. Microbial contamination may originate from different sources and includes the initial contamination of space flight materials during manufacturing and assembly, the delivery of supplies to the orbital station, the supplies themselves, secondary contamination during the lifetime of the orbital station, the crew and any other biological material on board e.g. animals, plants, micro-organisms used in scientific experiments. Although most microorganisms do not threaten human health, it has been reported that in a confined environment, such as a space cabin, microorganisms may produce adverse effects on the optimal performance of the space crew and the integrity of the spacecraft or habitat. These effects range from infections, allergies, and toxicities to degradation of air and water supplies. Biodegradation of critical materials may result in system failure and this may jeopardize the crew. The research aims at monitoring the biological airborne and surface contamination during manned space flight. The ISS has been selected as primary test bed for this study. The majority of the investigations are being done by the Russian Institute of Biomedical Problems (IBMP), which is responsible for monitoring the biological contamination in the habitable compartments of the ISS for safety and hygienic reasons. Within the frame of a collaboration between IBMP and the European Space Agency (ESA), SCK-CEN is able to participate in the analyses

  2. Mutation of the conserved Gly94 and Gly126 in elongation factor Tu from Escherichia coli. Elucidation of their structural and functional roles

    DEFF Research Database (Denmark)

    Knudsen, Charlotte Rohde; Kjaersgård, I V; Wiborg, O

    1995-01-01

    All guanine-nucleotide-binding proteins cycle between an inactive, GDP-bound and an active, GTP-bound conformation whereby they function as molecular switches. Elongation factor Tu from Escherichia coli is used as a model for defining residues important in the switch mechanism. Gly94 and Gly126...... were separately mutated to alanine residues to study their role in the switch mechanism. The mutant proteins are denoted [G94A]EF-Tu and [G126A]EF-Tu, respectively. Both mutations affect the affinities for guanine nucleotides considerably, resulting in a decrease in the characteristic preference...... for GDP over GTP. Furthermore the [G94A]EF-Tu mutant possesses an increased GTPase activity. The aminoacyl-tRNA affinity is much reduced for [G94A]EF-Tu, as reflected in an increase of the dissociation rate constant for the ternary complex by a factor of 40. Surprisingly, however, both mutants...

  3. Elongation Factor Ts Directly Facilitates the Formation and Disassembly of the Escherichia coli Elongation Factor Tu·GTP·Aminoacyl-tRNA Ternary Complex*

    Science.gov (United States)

    Burnett, Benjamin J.; Altman, Roger B.; Ferrao, Ryan; Alejo, Jose L.; Kaur, Navdep; Kanji, Joshua; Blanchard, Scott C.

    2013-01-01

    Aminoacyl-tRNA enters the translating ribosome in a ternary complex with elongation factor Tu (EF-Tu) and GTP. Here, we describe bulk steady state and pre-steady state fluorescence methods that enabled us to quantitatively explore the kinetic features of Escherichia coli ternary complex formation and decay. The data obtained suggest that both processes are controlled by a nucleotide-dependent, rate-determining conformational change in EF-Tu. Unexpectedly, we found that this conformational change is accelerated by elongation factor Ts (EF-Ts), the guanosine nucleotide exchange factor for EF-Tu. Notably, EF-Ts attenuates the affinity of EF-Tu for GTP and destabilizes ternary complex in the presence of non-hydrolyzable GTP analogs. These results suggest that EF-Ts serves an unanticipated role in the cell of actively regulating the abundance and stability of ternary complex in a manner that contributes to rapid and faithful protein synthesis. PMID:23539628

  4. Kreativitāte un sajūtu meklēšana jauniešiem

    OpenAIRE

    Tarhanova, Jekaterina

    2013-01-01

    Pētījuma mērķis bija izpētīt kreativitāti (radošumu) un sajūtu meklēšanu jauniešu populācijā. Sakarā ar to, ka pētījumu veica, lai iegūtu bakalaura grādu psiholoģijā, izlases apjoms bija tikai 75 cilvēki. Izlase tika veidota no studentiem vecumā no 18 līdz 23 gadiem. Cilvēki izpildīja Sajūtu Meklēšanas Skalas (Sensation Seeking Scale) MVU modificēto variantu un radošuma testu Zīmējumu pabeigšana (Complete Figures), kas ir Torensa Kreatīvās Domāšanas Testa (Torrance Test of Creative Thin...

  5. Molecular insight into γ-γ tubulin lateral interactions within the γ-tubulin ring complex (γ-TuRC)

    Science.gov (United States)

    Suri, Charu; Hendrickson, Triscia W.; Joshi, Harish C.; Naik, Pradeep Kumar

    2014-09-01

    γ-tubulin is essential for the nucleation and organization of mitotic microtubules in dividing cells. It is localized at the microtubule organizing centers and mitotic spindle fibres. The most well accepted hypothesis for the initiation of microtubule polymerization is that α/β-tubulin dimers add onto a γ-tubulin ring complex (γTuRC), in which adjacent γ-tubulin subunits bind to the underlying non-tubulin components of the γTuRC. This template thus determines the resulting microtubule lattice. In this study we use molecular modelling and molecular dynamics simulations, combined with computational MM-PBSA/MM-GBSA methods, to determine the extent of the lateral atomic interaction between two adjacent γ-tubulins within the γTuRC. To do this we simulated a γ-γ homodimer for 10 ns and calculated the ensemble average of binding free energies of -107.76 kcal/mol by the MM-PBSA method and of -87.12 kcal/mol by the MM-GBSA method. These highly favourable binding free energy values imply robust lateral interactions between adjacent γ-tubulin subunits in addition to their end-interactions longitudinally with other proteins of γTuRC. Although the functional reconstitution of γ-TuRC subunits and their stepwise in vitro assembly from purified components is not yet feasible, we nevertheless wanted to recognize hotspot amino acids responsible for key γ-γ interactions. Our free energy decomposition data from converting a compendium of amino acid residues identified an array of hotspot amino acids. A subset of such mutants can be expressed in vivo in living yeast. Because γTuRC is important for the growth of yeast, we could test whether this subset of the hotspot mutations support growth of yeast. Consistent with our model, γ-tubulin mutants that fall into our identified hotspot do not support yeast growth.

  6. The man and the hill

    Science.gov (United States)

    Leopold, Luna Bergere

    1962-01-01

    He was sitting on a large slab of rock. As he looked at the cloud of dust hanging hazily on the horizon, the piece of antler and the block of flint he held in his hand hung as if they were suspended from their previous rapid motion. The man gazed intently across the swaying grass which rose in wave-like billows across the distant hills. What was that dust - a herd of buffalo, a band of hunters, or were coyotes chasing the antelope again? After watching for a while he started again to chip the flint with a rapid twisting motion of the bone in his right hand. The little chips of flint fell in the grass before him. It is the same hill but the scene has changed. Seated on the same rock, holding the reins of a saddle horse, a man dressed in buckskin took the fur cap off his head and wiped his brow. He was looking intently across a brown and desolate landscape at a cloud of dust on the far horizon. Was it the hostile tribe of Indians? It could be buffalo. Nervously he kicked at the ground with the deerhide moccasin, pushing the flint chips out of the way. He wiped the dust from his long rifle. What a terrible place - no water, practically no grass, everything bare and brown. Now at sunset, slanting across the hills green with springtime, a cowman sits on a big rock, pushes his sombrero back on his head, and looks across the valley at a large but quiet herd of stock, moving slowly as each steer walks from one lush patch of grass to another, nibbling. Suddenly he stood up. Far on the horizon some dark objects were moving. Is it the sheepmen? Could it be the stage coach from Baggs to the Sweetwater Crossing?Same hill - a gray truck was grinding slowly toward the summit. It pulled up near a small fenced enclosure where there were some instruments painted a bright silver color. A man stepped out of the truck and turned to his younger companion, "You've never found an arrowhead? Maybe you have never thought about it correctly. If you want to find where an Indian camped long

  7. Transportvaneundersøgelsen - Variabeldeklaration : TU 2006-09, version 2

    DEFF Research Database (Denmark)

    Christiansen, Hjalmar

    , eller anden årsag. Undervejs omtales en række vigtige detaljer ved spørgeskemaet, men dette notat har ikke til formål at give en udtømmende beskrivelse af hvilke spørgsmål, der er stillet til hvem og hvornår. Her kan det være til stor nytte at besøge testspørgeskemaet på http://tu2010.dk/dev/starttest.php...

  8. The man and the universe

    Science.gov (United States)

    Kolodziejska, Magdalena

    2016-04-01

    The universe has always aroused people's curiosity. It fascinates and at the same time scares in its vastness. Encourages us to reflect of the meaning of human life. This begs the questions: whether there is a life beyond Earth? Whether is it possible that the man is alone in such a large space? These questions still remain unanswered, and topics concerning "the cosmos" constantly evoke many emotions. It is especially fascinating for the youngest students. Quite often, preschoolers can flawlessly name the planets according to their order of appearance in relation to the sun. They are happy to take the fun inspired by journeys into space. Teaching through action is extremely important for the development of the child-man* (Piaget, 2006). The thinking originates primarily from the action. Therefore, students should undertake independent research activities, perform experiments and conduct observations and thus raise questions about the world, looking for meanings and solutions. Adults (a teacher, a person with a passion) are to be the support in the search for knowledge, its processing and cleaning. Its role is to ensure a proper development of environment that is conducive to research activity. The answer to these requirements was to create in the oldest technical school in Poland (Railway Technical College, now Technical College No. 7) the astronomical observatory, which can be used by pupils of Warsaw's kindergartens and schools. There are organized activities for children and youth in this school, as well as trainings for teachers. Younger students during such an interdisciplinary courses are, among others, the opportunity to get acquainted with the construction of the telescope, they can build their own rockets and organize their racing or create your own star constellations. Older students as a result of observations and experiments may confirm or refute the hypothesis that the universe is within each of us. The classes are enriched using applications on

  9. 33 CFR 143.407 - Manning.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Manning. 143.407 Section 143.407 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES DESIGN AND EQUIPMENT Standby Vessels § 143.407 Manning. Standby vessels must be crewed...

  10. Alternative Frameworks for the Study of Man.

    Science.gov (United States)

    Markova, Ivana

    1979-01-01

    Two frameworks for the study of man are discussed. The Cartesian model views man as a physical object. A dialectic framework, with the emphasis on the self, grew out of nineteenth century romanticism and reflects the theories of Hegel. Both models have had an effect on social psychology and the study of interpersonal communication. (BH)

  11. A methodology for costing man-rem

    International Nuclear Information System (INIS)

    Bieber, C.

    1976-03-01

    An attempt is made to provide a methodology for costing man-rem in a way that can be applied to station conditions, based on 1974 Pickering G.S. data. Factors taken into account were social costs, exposure costs (dose accounting, training, dosimetry) temporary labour costs, and permanent replacement labour costs. A figure of $620/ man-rem was derived. (LL)

  12. Marihuana in Man: Three Years Later

    Science.gov (United States)

    Hollister, Leo E.

    1971-01-01

    Reviews three years of research on the effects of marihuana in man. Previously known clinical mental and physical effects have been confirmed. Causes and mechanisms of these effects generally remain undetermined in man and animals. Social implications and long term effects require additional study, although usage appears detrimental. (JM)

  13. Human Behaviour and the Origin of Man

    Science.gov (United States)

    Raleigh, M. J.; Washburn, S. L.

    1973-01-01

    The study of origin and evolution of man gives new perspective for understanding his behavior. Physical behaviors such as walking and throwing are results of biological evolution which has not kept pace with sociocultural evolution. Irrational decisions by man in social, cultural, and political fields are results of this brain activity. (PS)

  14. Human factors and man-machine-interaction

    International Nuclear Information System (INIS)

    Bohr-Bruckmayr, E.

    1985-01-01

    Definitions of the man-machine-interface concept are given. The importance of ergonomics in planning, construction, start-up and operation of a nuclear power plant is highlighted. A comprehensive task analysis is the basis of man-machine-interaction. Personnel performance, work shaping and security are discussed

  15. The Aging of Iron Man

    Directory of Open Access Journals (Sweden)

    Azhaar Ashraf

    2018-03-01

    Full Text Available Brain iron is tightly regulated by a multitude of proteins to ensure homeostasis. Iron dyshomeostasis has become a molecular signature associated with aging which is accompanied by progressive decline in cognitive processes. A common theme in neurodegenerative diseases where age is the major risk factor, iron dyshomeostasis coincides with neuroinflammation, abnormal protein aggregation, neurodegeneration, and neurobehavioral deficits. There is a great need to determine the mechanisms governing perturbations in iron metabolism, in particular to distinguish between physiological and pathological aging to generate fruitful therapeutic targets for neurodegenerative diseases. The aim of the present review is to focus on the age-related alterations in brain iron metabolism from a cellular and molecular biology perspective, alongside genetics, and neuroimaging aspects in man and rodent models, with respect to normal aging and neurodegeneration. In particular, the relationship between iron dyshomeostasis and neuroinflammation will be evaluated, as well as the effects of systemic iron overload on the brain. Based on the evidence discussed here, we suggest a synergistic use of iron-chelators and anti-inflammatories as putative anti-brain aging therapies to counteract pathological aging in neurodegenerative diseases.

  16. Transuranic element pathways to man

    International Nuclear Information System (INIS)

    Bennett, B.G.

    1976-01-01

    Transfer to man of transuranic element contamination may occur by the inhalation or ingestion pathways. The measurements of globally dispersed fall-out radioactivity have provided pertinent data on the environmental behaviour of plutonium. Additional data may eventually become available for americium. From the measured and inferred concentrations of fall-out plutonium, the inhalation intake has been determined and the ICRP Task Group lung model used to estimate deposition in the lung and transfer to other body organs. The computed body burden reached a maximum of 4pCi in 1964 and is currently about 2.5pCi. A complete diet sampling has been conducted to determine ingestion intake. Plutonium concentration in food ranged from 0.01pCi/kg in shellfish to undetected (less than 0.0003pCi/kg) in milk. Annual intake in total diet is estimated to have been 1.6pCi in 1972. Low uptake by the gastrointestinal tract makes contribution to organ burdens from ingestion negligible. Long-term pathway considerations include plant uptake from the cumulative deposit in soil and resuspension. Downward movement in soil may limit the significance of these long-term pathway components. (author)

  17. The Aging of Iron Man.

    Science.gov (United States)

    Ashraf, Azhaar; Clark, Maryam; So, Po-Wah

    2018-01-01

    Brain iron is tightly regulated by a multitude of proteins to ensure homeostasis. Iron dyshomeostasis has become a molecular signature associated with aging which is accompanied by progressive decline in cognitive processes. A common theme in neurodegenerative diseases where age is the major risk factor, iron dyshomeostasis coincides with neuroinflammation, abnormal protein aggregation, neurodegeneration, and neurobehavioral deficits. There is a great need to determine the mechanisms governing perturbations in iron metabolism, in particular to distinguish between physiological and pathological aging to generate fruitful therapeutic targets for neurodegenerative diseases. The aim of the present review is to focus on the age-related alterations in brain iron metabolism from a cellular and molecular biology perspective, alongside genetics, and neuroimaging aspects in man and rodent models, with respect to normal aging and neurodegeneration. In particular, the relationship between iron dyshomeostasis and neuroinflammation will be evaluated, as well as the effects of systemic iron overload on the brain. Based on the evidence discussed here, we suggest a synergistic use of iron-chelators and anti-inflammatories as putative anti-brain aging therapies to counteract pathological aging in neurodegenerative diseases.

  18. Manned spacecraft electrical power systems

    Science.gov (United States)

    Simon, William E.; Nored, Donald L.

    1987-01-01

    A brief history of the development of electrical power systems from the earliest manned space flights illustrates a natural trend toward a growth of electrical power requirements and operational lifetimes with each succeeding space program. A review of the design philosophy and development experience associated with the Space Shuttle Orbiter electrical power system is presented, beginning with the state of technology at the conclusion of the Apollo Program. A discussion of prototype, verification, and qualification hardware is included, and several design improvements following the first Orbiter flight are described. The problems encountered, the scientific and engineering approaches used to meet the technological challenges, and the results obtained are stressed. Major technology barriers and their solutions are discussed, and a brief Orbiter flight experience summary of early Space Shuttle missions is included. A description of projected Space Station power requirements and candidate system concepts which could satisfy these anticipated needs is presented. Significant challenges different from Space Shuttle, innovative concepts and ideas, and station growth considerations are discussed. The Phase B Advanced Development hardware program is summarized and a status of Phase B preliminary tradeoff studies is presented.

  19. Cosmic evolution, life and man

    International Nuclear Information System (INIS)

    Oro, J.

    1995-01-01

    Among the most basic problems confronting science are those regarding the origin of the universe, the origin of life and the origin of man. This general overview starts (1) with a brief introduction addressed primarily to the Cyril Ponnamperuma Memorial. Then, the thesis is presented that the appearance of life and intelligence on our planet can be understood as the result of a number of cosmic and biological evolutionary processes, including (2) the stellar thermonuclear synthesis of the biogenic elements other than hydrogen (C, N, O, P and S), their dispersal into space, and their combination into circumstellar and interstellar molecules. (3) The formation of the Solar System and the Earth-Moon System. (4) The role of comets and carbonaceous chondrites in contributing organic matter to the primitive Earth. (5) The prebiotics synthesis of amino acids, purines, pyrimidines, fatty acids, and other biochemical monomers. (6) The prebiotic condensation reactions leading to the synthesis of oligomers such as oligonucleotides and oligopeptides, with replicative and catalytic activities. (7) The synthesis of amphiphilic lipids, and their self-assembly into liposomes with bi-layered membranes. (8) The formation of protocellular structures. (9) The activation of protocells into a functioning Darwin's ancestral cell. (10) Early evolution of life. (11) The K-T boundary event and the disappearance of dinosaurs. (12) Evolution of hominids leading to Homo sapiens. (13) The rapid development of civilization. (14) The exploration of the Solar System. (15) Life beyond our planetary system. (16) Epilogue. Peace from cosmic evolution? (Abstract only)

  20. Cosmic evolution, life and man

    Energy Technology Data Exchange (ETDEWEB)

    Oro, J [Houston Univ., Houston, TX (United States). Dept. of Biochemical and Biophysical Sciences

    1995-08-01

    Among the most basic problems confronting science are those regarding the origin of the universe, the origin of life and the origin of man. This general overview starts (1) with a brief introduction addressed primarily to the Cyril Ponnamperuma Memorial. Then, the thesis is presented that the appearance of life and intelligence on our planet can be understood as the result of a number of cosmic and biological evolutionary processes, including (2) the stellar thermonuclear synthesis of the biogenic elements other than hydrogen (C, N, O, P and S), their dispersal into space, and their combination into circumstellar and interstellar molecules. (3) The formation of the Solar System and the Earth-Moon System. (4) The role of comets and carbonaceous chondrites in contributing organic matter to the primitive Earth. (5) The prebiotics synthesis of amino acids, purines, pyrimidines, fatty acids, and other biochemical monomers. (6) The prebiotic condensation reactions leading to the synthesis of oligomers such as oligonucleotides and oligopeptides, with replicative and catalytic activities. (7) The synthesis of amphiphilic lipids, and their self-assembly into liposomes with bi-layered membranes. (8) The formation of protocellular structures. (9) The activation of protocells into a functioning Darwin`s ancestral cell. (10) Early evolution of life. (11) The K-T boundary event and the disappearance of dinosaurs. (12) Evolution of hominids leading to Homo sapiens. (13) The rapid development of civilization. (14) The exploration of the Solar System. (15) Life beyond our planetary system. (16) Epilogue. Peace from cosmic evolution? (Abstract only).

  1. Human capabilities in space. [man machine interaction

    Science.gov (United States)

    Nicogossian, A. E.

    1984-01-01

    Man's ability to live and perform useful work in space was demonstrated throughout the history of manned space flight. Current planning envisions a multi-functional space station. Man's unique abilities to respond to the unforeseen and to operate at a level of complexity exceeding any reasonable amount of previous planning distinguish him from present day machines. His limitations, however, include his inherent inability to survive without protection, his limited strength, and his propensity to make mistakes when performing repetitive and monotonous tasks. By contrast, an automated system does routine and delicate tasks, exerts force smoothly and precisely, stores, and recalls large amounts of data, and performs deductive reasoning while maintaining a relative insensitivity to the environment. The establishment of a permanent presence of man in space demands that man and machines be appropriately combined in spaceborne systems. To achieve this optimal combination, research is needed in such diverse fields as artificial intelligence, robotics, behavioral psychology, economics, and human factors engineering.

  2. Preventive Effect of TU-100 on a Type-2 Model of Colitis in Mice: Possible Involvement of Enhancing Adrenomedullin in Intestinal Epithelial Cells

    Directory of Open Access Journals (Sweden)

    Atsushi Kaneko

    2013-01-01

    Full Text Available Purpose. Crohn's disease (CD and ulcerative colitis (UC, the two major forms of inflammatory bowel disease (IBD, have histopathologically and immunologically different characteristics. We previously reported that a traditional Japanese medicine, daikenchuto (TU-100, ameliorated a trinitrobenzenesulfonic acid- (TNBS- induced type-1 model colitis exhibiting histopathological features of CD through adrenomedullin (ADM enhancement. Our current aims were to examine whether TU-100 ameliorates a type-2 model colitis that histologically resembles UC and identify the active ingredients. Methods. TU-100 was administered orally to mice with oxazolone- (OXN- induced type-2 model colitis. The morbidity was evaluated by body weight loss and the macroscopic score of colonic lesions. ADM was quantified using an EIA kit. Results. TU-100 prevented weight loss and colon ulceration. ADM production by intestinal epithelial cells was increased by TU-100 addition. Screening to identify active ingredients showed that [6]-shogaol and hydroxy α-sanshool enhanced ADM production. Conclusions. TU-100 exerted a protective effect in OXN-induced type-2 model colitis, indicating that TU-100 may be a beneficial agent for treatment of UC.

  3. An improved method for determining the purity of jet fuels in a POZ-TU instrument

    Energy Technology Data Exchange (ETDEWEB)

    Zrelov, V N; Fedotkin, B I; Krasnaya, L V; Nikitin, L V; Postinkova, N G

    1983-01-01

    The possibility is studied of real time testing for the content of mechanical impurities (Cm.t.) in jet fuels (RT) in a POZ-TU instrument. Based on the obtained data, a four point scale of gray standards is developed for determining the mechanical impurity content, which is four rounded, gray stamps of different intensity, which corresponds to a mechanical impurity content of 0.5; 1.0; 2.0 and 3.0 milligrams per liter. A white indicator filtering element is built into the POZ-TU for determining the mechanical impurity content, and 50 cubic centimeters of the jet fuel are pumped through it over the course of several seconds. The mechanical impurities are placed on the indicator element, forming an imprint, the intensity of the color of which corresponds to the content of mechanical impurities in the jet fuel. The indicator element is extracted from the instrument and the prints are compared with the scale of gray standards, from which the content of the mechanical impurities is determined.

  4. The "Da Ming Hunyi Tu": Repurposing a Ming Map in Sino-African Diplomacy

    Directory of Open Access Journals (Sweden)

    Alexander Akin

    2016-12-01

    Full Text Available In 2002, an exhibition at South Africa’s parliament included a reproduction of the Da Ming Hunyi Tu (Amalgamated map of the Great Ming, citing it as the earliest world map to depict the entire African continent. As part of its broader efforts to shape a narrative of long-standing and peaceful international relations with Africa, the People’s Republic of China formally presented a replica of this map as a gift to the South African government in conjunction with the exhibition. In official statements and popular media coverage alike, the map was described as evidence of a distinctly Chinese approach to global relations, based on benevolence and mutual respect. In particular, the map was ahistorically intertwined with the legacy of Zheng He’s diplomatic expeditions, which reached the East African coast in the early 1400s. To the cartographic historian, however, the depiction of Africa in the Da Ming Hunyi Tu is clearly derived from non-Chinese sources that predate Zheng He’s expeditions. This article examines the ways in which the map has been divorced from its original context to suit modern needs, exemplifying the deployment of cartography to deflect anxieties about the nature of Chinese economic influence in South Africa.

  5. TuBaFrost 5: multifunctional central database application for a European tumor bank.

    Science.gov (United States)

    Isabelle, M; Teodorovic, I; Morente, M M; Jaminé, D; Passioukov, A; Lejeune, S; Therasse, P; Dinjens, W N M; Oosterhuis, J W; Lam, K H; Oomen, M H A; Spatz, A; Ratcliffe, C; Knox, K; Mager, R; Kerr, D; Pezzella, F; van de Vijver, M; van Boven, H; Alonso, S; Kerjaschki, D; Pammer, J; Lopez-Guerrero, J A; Llombart Bosch, A; Carbone, A; Gloghini, A; van Veen, E-B; van Damme, B; Riegman, P H J

    2006-12-01

    Developing a tissue bank database has become more than just logically arranging data in tables combined with a search engine. Current demand for high quality samples and data, and the ever-changing legal and ethical regulations mean that the application must reflect TuBaFrost rules and protocols for the collection, exchange and use of tissue. To ensure continuation and extension of the TuBaFrost European tissue bank, the custodianship of the samples, and hence the decision over whether to issue samples to requestors, remains with the local collecting centre. The database application described in this article has been developed to facilitate this open structure virtual tissue bank model serving a large group. It encompasses many key tasks, without the requirement for personnel, hence minimising operational costs. The Internet-accessible database application enables search, selection and request submission for requestors, whereas collectors can upload and edit their collection. Communication between requestor and involved collectors is started with automatically generated e-mails.

  6. An Interbacterial NAD(P)+ Glycohydrolase Toxin Requires Elongation Factor Tu for Delivery to Target Cells

    Energy Technology Data Exchange (ETDEWEB)

    Whitney, John C.; Quentin, Dennis; Sawai, Shin; LeRoux, Michele; Harding, Brittany N.; Ledvina, Hannah E.; Tran, Bao Q.; Robinson, Howard; Goo, Young Ah; Goodlett, David R.; Raunser, Stefan; Mougous, Joseph D.

    2015-10-08

    Type VI secretion (T6S) influences the composition of microbial communities by catalyzing the delivery of toxins between adjacent bacterial cells. Here, we demonstrate that a T6S integral membrane toxin from Pseudomonas aeruginosa, Tse6, acts on target cells by degrading the universally essential dinucleotides NAD+ and NADP+. Structural analyses of Tse6 show that it resembles mono-ADP-ribosyltransferase proteins, such as diphtheria toxin, with the exception of a unique loop that both excludes proteinaceous ADP-ribose acceptors and contributes to hydrolysis. We find that entry of Tse6 into target cells requires its binding to an essential housekeeping protein, translation elongation factor Tu (EF-Tu). These proteins participate in a larger assembly that additionally directs toxin export and provides chaperone activity. Visualization of this complex by electron microscopy defines the architecture of a toxin-loaded T6S apparatus and provides mechanistic insight into intercellular membrane protein delivery between bacteria.

  7. On the identity of Dorylaimus robustus de Man

    NARCIS (Netherlands)

    Loof, P.A.A.

    1961-01-01

    The taxonomic position of Dorylaimus robustus de Man, 1876 is fully discussed. It is concluded that D. robustus de Man, 1876 is a synonym of D. stagnalis Dujardin, 1845; also included in this synonymy are D. robustus apud de Man, 1880, apud de Man, 1884 (male, partim) and Labronema robustum (de Man,

  8. The YvfTU Two-component System is involved in plcR expression in Bacillus cereus

    NARCIS (Netherlands)

    Brillard, Julien; Susanna, Kim; Michaud, Caroline; Dargaignaratz, Claire; Gohar, Michel; Nielsen-Leroux, Christina; Ramarao, Nalini; Kolsto, Anne-Brit; Nguyen-The, Christophe; Lereclus, Didier; Broussolle, Veronique

    2008-01-01

    Background: Most extracellular virulence factors produced by Bacillus cereus are regulated by the pleiotropic transcriptional activator PlcR. Among strains belonging to the B. cereus group, the plcR gene is always located in the vicinity of genes encoding the YvfTU two-component system. The putative

  9. Crosslinking of tRNA containing a long extra arm to elongation factor Tu by trans-diamminedichloroplatinum(II)

    DEFF Research Database (Denmark)

    Rasmussen, Nils-Jørgen; Wikman, Friedrik; Clark, Brian F. C.

    1990-01-01

    A tRNA containing a long extra arm, namely E. coli tRNA1Leu has been crosslinked to elongation factor Tu, with the crosslinking reagent trans-diamminedichloroplatinum(II). The nucleotide involved in the crosslinking was identified to be a guanosine in the variable region at position 47F or 47G....

  10. Mitochondrial translation factors of Trypanosoma brucei: elongation factor-Tu has a unique subdomain that is essential for its function

    Czech Academy of Sciences Publication Activity Database

    Cristodero, M.; Mani, J.; Oeljeklaus, S.; Aeberhard, L.; Hashimi, Hassan; Ramrath, D.J.F.; Lukeš, Julius; Warscheid, B.; Schneider, A.

    2013-01-01

    Roč. 90, č. 4 (2013), s. 744-755 ISSN 0950-382X R&D Projects: GA ČR GAP305/12/2261 Institutional support: RVO:60077344 Keywords : mitochondrial translation * Trypanosoma brucei * EF-Tu Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 5.026, year: 2013

  11. The surface-associated elongation factor Tu is concealed for antibody binding on viable pneumococci and meningococci

    Czech Academy of Sciences Publication Activity Database

    Kolberg, J.; Hammerschmidt, S.; Frank, R.; Jonák, Jiří; Šanderová, Hana; Aase, A.

    2008-01-01

    Roč. 53, č. 2 (2008), s. 222-230 ISSN 0928-8244 R&D Projects: GA AV ČR KJB500520503 Institutional research plan: CEZ:AV0Z50520514; CEZ:AV0Z50200510 Keywords : Streptococcus pneumoniae * Neisseria meningitidis * elongation factor EF-Tu Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 1.972, year: 2008

  12. Rodents from the Upper Miocene Tuğlu Formation (Çankırı Basin, Central Anatolia, Turkey)

    NARCIS (Netherlands)

    Joniak, Peter; de Bruijn, Hans

    2015-01-01

    The upper Miocene assemblages of rodents collected from two layers of the type section of the Tuğlu Formation (Çankırı Basin, Central Anatolia, Turkey) are described. The assemblage from the lower level is considerably less diverse than that from the upper level. It contains Progonomys together with

  13. Understanding Spider-Man: Your Everyday Superhero

    OpenAIRE

    Falk, Nicklas; Blomsterberg, Sofie Amalie; Suciu, Alice Sabrina; Pedersen, Mads Peter; Lucas, Vilhelm

    2014-01-01

    This project focuses on the understanding of Spider-Man, and the morals and ethics that lie behind the choices he makes. Through the Dimensions Philosophy & Science/Text & Sign, this understanding is concluded by looking at ethical theories and comic book analysis. Based on the Ultimate Spider-Man comic book series, the aim is to clarify who Spider-Man is and what causes him to act in certain ways; before and after his realization of power. Some theories used to investigate these area...

  14. Man-made gemstones; Jinko hoseki

    Energy Technology Data Exchange (ETDEWEB)

    Isogami, M. [Kyocera Corp., Kyoto (Japan)

    2000-01-01

    Birth and development of the man-made gemstones in the 20th century are outlined. Manufacturing gemstones was initiated by the invention of corundum production, followed by production of rubies and sapphires. In 1950 GE Co. synthesized diamonds, after that, most gemstones were manufactured consequently by progress of technologies of single crystal growing and ceramic manufacturing. In the 21st century, steep growth in demand is not expected but it seems to keep steady growth and the importance and necessity of man-made gemstones may be increased because of global environmental issues. Man-made gemstones seem to have both personality and variety of characteristics. (NEDO)

  15. Laser Pyro System Standardization and Man Rating

    Science.gov (United States)

    Brown, Christopher W.

    2004-01-01

    This viewgraph presentation reviews an X-38 laser pyro system standardization system designed for a new manned rated program. The plans to approve this laser initiation system and preliminary ideas for this system are also provided.

  16. Man-made climate change: an overview

    Energy Technology Data Exchange (ETDEWEB)

    Holopainen, E [Helsinki Univ. (Finland). Dept. of Meteorology

    1996-12-31

    The first major man-made environmental problem was the soil acidification, caused primarily by the massive industrial emissions of sulphur dioxide. Then came the problem of ozone depletion, caused by the emissions of man-made halocarbons. More recently, the possibility of man-made climate change has received a lot of attention. These three man-made problems are interconnected in fundamental ways and require for their solution interdisciplinary and international approach. Narrowing of the scientific uncertainties connected with the problems mentioned above can be expected through international `Global Change` programmes such as the World Climate Research Programme (WCRP) and the International Geosphere-Biosphere Programme (IGBP). Periodic assessments of the type produced by the IPCC will clearly be needed. Also in the future such assessments should form the scientific basis for international negotiations and conventions on the climate change issue

  17. Don't Trust the Big Man

    National Research Council Canada - National Science Library

    Coerr, Stanton S

    2008-01-01

    .... A full-length analysis of the Democratic Republic of the Congo and its full-scale insurgencies since 1960 -- at the hands of Big Man leaders Lumumba, Mobutu, and Kabila -- provide object lessons...

  18. Synergistic Man: Outcome Model for Counselors

    Science.gov (United States)

    Rousseve, Ronald J.

    1973-01-01

    Drawing on the insights of Ruth Benedict and Abraham Maslow in their search for an ethical gauge by which to rate personal-social health, this article proposes synergistic man'' as the desired outcome model for counselors. (Author)

  19. Nuclear fuel: the thinking man's alternative

    International Nuclear Information System (INIS)

    Chamberlain, N.

    1989-01-01

    'Nuclear Fuel ' The Thinking Man's Alternative' is the title of the 55th Melchett Lecture given by Neville Chamberlain, Chief Executive of British Nuclear Fuels plc. This article is based on the address, the essence of which is that the case for nuclear power should be based upon an appreciation of the totality and sophistication of man's handling of his energy needs - not on a glib catch-phase or on a simple political dogma or on an economic argument. Arguments in favour of nuclear power were discussed. The conclusion was that nuclear energy is the thinking man's alternative because only thinking man could have and can develop it; secondly, only thinking men should be authorized to exploit and control it; thirdly, a thinking person will appreciate that, properly thought out and controlled, it must be the most important source of future energy for the benefit of mankind. (author)

  20. Long term effects of radiation in man

    International Nuclear Information System (INIS)

    Tso Chih Ping; Idris Besar

    1984-01-01

    An overview of the long term effects of radiation in man is presented, categorizing into somatic effects, genetic effects and teratogenic effects, and including an indication of the problems that arise in their determination. (author)

  1. Environmental Education: The Whole Man Revisited

    Science.gov (United States)

    Kormondy, Edward J.

    1971-01-01

    Environmental education is seen as an interdisciplinary study of the ecology of man, viewed in his totality, in all his dimensions. Biology is not considered the central discipline in this study. (Author/AL)

  2. A report on reference Japanese man

    International Nuclear Information System (INIS)

    1979-01-01

    In connection with the reference Japanese man for evaluation of accurate exposure doses considering the various characteristics, survey data of organs etc. weights and dimensions are given: renal glands, brains, kidneys, liver, lungs, womb, thyroid glands, gallbladder, stomach. (Mori, K.)

  3. Pet Therapy: Man's Best Friend as Healer

    Science.gov (United States)

    ... psychological and physiological health of critically ill patients. Dimensions of Critical Care Nursing. 2010;29:211. Cangelosi PR, et al. Walking for therapy with man's best friend. Journal of Psychosocial Nursing and Mental ...

  4. Man-made climate change: an overview

    Energy Technology Data Exchange (ETDEWEB)

    Holopainen, E. [Helsinki Univ. (Finland). Dept. of Meteorology

    1995-12-31

    The first major man-made environmental problem was the soil acidification, caused primarily by the massive industrial emissions of sulphur dioxide. Then came the problem of ozone depletion, caused by the emissions of man-made halocarbons. More recently, the possibility of man-made climate change has received a lot of attention. These three man-made problems are interconnected in fundamental ways and require for their solution interdisciplinary and international approach. Narrowing of the scientific uncertainties connected with the problems mentioned above can be expected through international `Global Change` programmes such as the World Climate Research Programme (WCRP) and the International Geosphere-Biosphere Programme (IGBP). Periodic assessments of the type produced by the IPCC will clearly be needed. Also in the future such assessments should form the scientific basis for international negotiations and conventions on the climate change issue

  5. İnternet ve Tuğla-Harç Mağazalarına İlişkin Müşteri Düşünceleri ve Değişen Müşteri Davranışları

    Directory of Open Access Journals (Sweden)

    Abdolrazagh MADAHI

    2014-09-01

    Full Text Available Bu çalışma Malezya’da internette faaliyet gösteren tuğla harç mağazalarına ilişkin müşteri düşüncelerini ve müşterilerin değişen kanal eğilimlerini analiz etmeyi amaçlamaktadır. Çalışmaya ilişkin veriler Klang Vadisi ve Penang Bölgesi’nde 497 kişinin katılımıyla gerçekleştirilen anketlerin neticesinde elde edilmiştir. Çalışmada yapısal bağlamda PLS Modeli ve data analizi bağlamında ise SEM Modeli kullanılmıştır. Yapılan 497 anketin neticesinde, çalışmanın verileri, uygunluk ve zorluk bağlamında internetten tuğla ve harç mağazalara doğru değişen bir eğilim olduğunu göstermiştir. Bulgular benzer şekilde cinsiyet ve niyetin de müşterilerin kanal değiştirmesinde etkin unsurlar olduğunu ortaya koymuştur.

  6. Crisis and Man: Literary Responses Across Cultures

    OpenAIRE

    Krishnaswami, Mallika

    2012-01-01

    Myth of Sisyphus exemplifies the situation man finds himself in irrespective of his ethnic and geographical background. Art and cultural forms gave expression to this situation and the intensity of the expression depended upon the political and social dimensions. War or peace, man is always condemned to struggle with his problems, moral or otherwise. Post war English writers focused on the social problems the British society found itself in and its helplessness in dealing with them. It was th...

  7. Woman Position In Iron Man Movies

    OpenAIRE

    ANINDITHA, ANNISA

    2014-01-01

    Aninditha, Annisa. 2014. Woman Position in Iron Man movies. Study Program ofEnglish, Department of Language and Literature, Faculty of Cultural Studies,Universitas Brawijaya, Malang. Supervisor: Fariska Pujiyanti. Co Supervisor: NurulLaily Nadhifah. Keywords: Movie, Patriarchal, Iron Man. Movie is one of literary works and electronic media. Movie becomes the best strategy to communicate and deliver message about what happens in this world. The movie makers or directors can express critics, co...

  8. Hvornår er man ung?

    DEFF Research Database (Denmark)

    Gundelach, Peter; Nørregård-Nielsen, Esther C.

    2002-01-01

    Hvornår er man ung, og hvornår er man voksen? Er der forskelle i befolkningens værdier i forhold til arbejde og politik, når det undersøges ud fra henholdsvis et alders- eller generationsperspektiv? Baseret på data fra den danske del af den internationale værdiundersøgelse vises at der er så store...

  9. The future of oil and hydrocarbon man

    CERN Document Server

    Campbell, Colin

    1999-01-01

    Man appeared on the planet about four million years ago, and by 1850 numbered about one billion Ten came Hydrocarbon man. World population has since increased six-fold. After the oil price shocks of the 1970s, people asked "when will production peak?". It is not easy to answer this question because of the very poor database. Reserves and the many different hydrocarbon categories are poorly defined, reporting practices are ambiguous, revisions are not backdated...

  10. 2009 Navy ManTech Project Book

    Science.gov (United States)

    2009-01-01

    build a hybrid laser / GMAW system that combined deep keyhole penetration of laser welding with the high metal deposition rate of GMAW, enabling...committed to the successful outcome of the ManTech project. In addition, this close working relationship between the parties provides ManTech with a longer...the cost and time to build and repair Navy ships. The Center works closely with the Navy’s acquisition community and the shipbuilding industry to

  11. A guidelines handbook for GPR surveys in tunnels: a COST Action TU1208 contribution

    Science.gov (United States)

    Bianchini Ciampoli, Luca; Alani, Amir M.; Pajewski, Lara; Benedetto, Andrea; Loizos, Andreas; Tosti, Fabio

    2016-04-01

    A significant open issue concerning the reliability of geophysical methods and in particular of ground penetrating radar (GPR), both in research and professional context, is a general lack of international standards. This is a major problem to be faced, in order to gain scientific strictness for the GPR practices, and to easily extend to the international community the results achieved within the area of single virtuous countries. Producing international guidelines can represent an important step forward, in this sense. In the memorandum of understanding of the COST Action TU1208 is clearly stated that one of the main purposes of the Action is the "development of innovative protocols and guidelines which will be published in a handbook and constitute a basis for European Standards, for an effective GPR application in CE tasks; safety, economic and financial criteria will be integrated within the protocols". Of course this is not a simple task to be accomplished. Firstly, survey procedures are highly dependent on the objective of the survey itself. On the basis of the objective of each geophysical test, the GPR system, the antenna configuration, and even the processing procedures may change. Besides, these procedures are also influenced by the environmental conditions in which the tests are performed. This affects several aspects spanning from hardware to software, but including, for instance, also safety issues. Due to these reasons, one of the main goal of the COST Action TU1208 is the development of several guidelines related to the main applications of GPR in the field of civil engineering. In this work, the structure of a guidelines handbook for GPR activities in tunnels is outlined. In the first sections, the principal references in the field are provided, and the most common GPR equipment and complementary technologies are described. Subsequently, the survey methodologies are explained. Particular attention is paid to the preliminary activities to be carried

  12. DNA Barcoding for Identification of "Candidatus Phytoplasmas" Using a Fragment of the Elongation Factor Tu Gene

    DEFF Research Database (Denmark)

    Makarova, Olga; Contaldo, Nicoletta; Paltrinieri, Samanta

    2012-01-01

    Background Phytoplasmas are bacterial phytopathogens responsible for significant losses in agricultural production worldwide. Several molecular markers are available for identification of groups or strains of phytoplasmas. However, they often cannot be used for identification of phytoplasmas from...... different groups simultaneously or are too long for routine diagnostics. DNA barcoding recently emerged as a convenient tool for species identification. Here, the development of a universal DNA barcode based on the elongation factor Tu (tuf) gene for phytoplasma identification is reported. Methodology....../Principal Findings We designed a new set of primers and amplified a 420–444 bp fragment of tuf from all 91 phytoplasmas strains tested (16S rRNA groups -I through -VII, -IX through -XII, -XV, and -XX). Comparison of NJ trees constructed from the tuf barcode and a 1.2 kbp fragment of the 16S ribosomal gene revealed...

  13. “En tu casa o en la mía’: the interview as infotainment

    Directory of Open Access Journals (Sweden)

    Marián Alonso González

    2016-11-01

    Full Text Available The fight for viewers has led to a spectacular range of television content on offer where boundaries of genres have disappeared giving rise to new formats of hybrid television programmes. This has given a new lease of life to interviews as a genre of infotainment. The present article analyses the programme ‘En tu casa o en la mía’, a new type of interview of famous personalities which combines information and entertainment with elements that are very similar to the info-show. We shall embark on a study of this media product, its narrative, treatment, structure and the technique used so as to describe the elements that make it an example of gender hybridization in today’s television programmes.

  14. Joint efforts to harmonize sound insulation descriptors and classification schemes in Europe (COST TU0901)

    DEFF Research Database (Denmark)

    Rasmussen, Birgit

    2010-01-01

    Sound insulation descriptors, regulatory requirements and classification schemes in Europe represent a high degree of diversity. One implication is very little exchange of experience of housing design and construction details for different levels of sound insulation; another is trade barriers...... for building systems and products. Unfortunately, there is evidence for a development in the "wrong" direction. For example, sound classification schemes for dwellings exist in nine countries. There is no sign on increasing harmonization, rather the contrary, as more countries are preparing proposals with new......, new housing must meet the needs of the people and offer comfort. Also for existing housing, sound insulation aspects should be taken into account, when renovating housing; otherwise the renovation is not “sustainable”. A joint European Action, COST TU0901 "Integrating and Harmonizing Sound Insulation...

  15. Housing for the poor: Implementation and impact of Tu Casa program in Tijuana

    Directory of Open Access Journals (Sweden)

    Ana Elizabeth Jardón Hernández

    2009-01-01

    Full Text Available This study assesses the operation and some major results of most important federal housing program focus on households in poverty situation, with particular emphasis on their instrumentation process and impacts in Tijuana’s housing problem for poor families. The exam aims to analyses the design changes of the program that forced its transformation from Vivah to Tu Casa, and the operational difficulties for a proper implementation in an urban context, as well as its limited impact for solving popular housing needs. It also seeks to weigh the importance of government subsidies to acquire or improve housing, in their progressive modality, as an alternative for social segments excluded from any other public or private financing option.

  16. Some consideration of Japanese standard man value

    International Nuclear Information System (INIS)

    Yoshizawa, Yasuo; Kusama, Tomoko

    1976-01-01

    Numerical values of standard man or reference man is important problem in the field of radiation protection and safety. The standard man values given by ICRP were obtained from European and North American adult data. For that reason, there are some theoretical problems in the application of standard man values to Japanese. The purpose of the present paper is to consider the difference of values between Japanese and standard man. The standard man values are divided into three categories. The first category is the size and weight of the body or organ, the second is the values of elementary composition, and the third is the numerical factors related to metabolic kinetics. It is natural that some values of the second and the third categories have little difference between Japanese and European. On the other hand, there are some differences in the value of the first category, but the differences can calculation in proportional allotment to the body weight. The values concerning the thyroid gland and iodine metabolism are important for radiation protection. It has been foreseen that these values of Japanese are significantly different from standard man. A survey of past reports was carried out with a view to search for normal values of the weight, iodine content, and iodine uptake rate of the thyroid of Japanese. The result of the survey showed that the weight of thyroid are about 19g for adult male and 17g for adult female and that the iodine contents are 12-22mg and iodine uptake rate (fw) is about 0.2. (auth.)

  17. A avaliação da concordância verbal com o pronome tu em Florianópolis

    Directory of Open Access Journals (Sweden)

    Christiane Maria Nunes de Souza

    2015-09-01

    Full Text Available http://dx.doi.org/10.5007/1984-8420.2015v16n1p170 Neste artigo, com base nos pressupostos da Sociolinguística Variacionista (WEINREICH, LABOV, HERZOG, 1968; LABOV, 1972, 1982, 1994, 2001, 2010, buscamos indícios de como o fenômeno variável de concordância verbal com o pronome tu (tu/Ø falas ~ tu/Ø fala, tu/Ø  falaste ~ tu/Ø falasse ~ tu/Ø falou é avaliado na cidade de Florianópolis. Com essa finalidade, aplicamos um teste de avaliação a 22 alunos do curso de Economia da Universidade Federal de Santa Catarina (UFSC. Os resultados evidenciam uma correlação entre a diminuição das taxas percentuais de concordância verificada em Florianópolis (LOREGIAN-PENKAL, 2004; DAVET, 2013 e uma avaliação positiva/neutra da não marcação da concordância.

  18. Man and technology in the future

    International Nuclear Information System (INIS)

    1993-01-01

    The Royal Swedish Academy of Engineering Sciences has set up a committee known as The Committee of Man, Technology and Society. The members of this committee form an interdisciplinary group for the study of the interaction between scientific and technological advances and the way in which society evolves. Most of the committees activities have focused on the present relationship between man, technology and society. Attempts have been made to assess the future influence on society of key developments in biotechnology, electronic communication and systems analysis. In order to pursue this path still further, the committee decided to arrange an international symposium on the topic Man and Technology in the Future at the village of Forsmark on the Baltic coast of Sweden. The proceedings consists of 13 lectures centered on energy systems - and the connected waste problems, biotechnology, and telecommunications. Separate abstracts were prepared for 5 of the lectures in this volume

  19. Oedipus king: preparing man for the polis

    Directory of Open Access Journals (Sweden)

    José Joaquim Pereira Melo

    2013-09-01

    Full Text Available Having Sophoclean play Oedipus King as a frame of reference, the purpose of this paper is to discuss the educative proposal conceived to the Greek Man as preparation for life in the polis. Although not intentionally, Sophocles pointed out an ideal of Man which, in his perspective, would fulfill Greek societal demands of that time. Such society was divided between myth and rationality and, as a result, Man found Himself in conflict and lacking direction for His life. Given that, Oedipus’ character represented the ideal behavior of that society, and it also made it possible for citizens to reflect and to discuss social, economic and political transformations taking place at that period. Thus Sophocles came up with a hero who was an educational model and a citizen’s as well. Furthermore, such hero differed from that one of the archaic Greek thought.

  20. Progress of the COST Action TU1402 on the Quantification of the Value of Structural Health Monitoring

    DEFF Research Database (Denmark)

    Thöns, Sebastian; Limongelli, Maria Pina; Ivankovic, Ana Mandic

    2017-01-01

    This paper summarizes the development of Value of Structural Health Monitoring (SHM) Information analyses and introduces the development, objectives and approaches of the COST Action TU1402 on this topic. SHM research and engineering has been focused on the extraction of loading, degradation...... for its quantification. This challenge can be met with Value of SHM Information analyses facilitating that the SHM contribution to substantial benefits for life safety, economy and beyond can be may be quantified, demonstrated and utilized. However, Value of SHM Information analyses involve complex models...... encompassing the infrastructure and the SHM systems, their functionality and thus require the interaction of several research disciplines. For progressing on these points, a scientific networking and dissemination project namely the COST Action TU1402 has been initiated....

  1. Man-machine dialogue design and challenges

    CERN Document Server

    Landragin, Frederic

    2013-01-01

    This book summarizes the main problems posed by the design of a man-machine dialogue system and offers ideas on how to continue along the path towards efficient, realistic and fluid communication between humans and machines. A culmination of ten years of research, it is based on the author's development, investigation and experimentation covering a multitude of fields, including artificial intelligence, automated language processing, man-machine interfaces and notably multimodal or multimedia interfaces. Contents Part 1. Historical and Methodological Landmarks 1. An Assessment of the Evolution

  2. Ocular bacillary angiomatosis in an immunocompromised man.

    Science.gov (United States)

    Murray, Meltzer A; Zamecki, Katherine J; Paskowski, Joseph; Lelli, Gary J

    2010-01-01

    An immunocompromised man presented with an inflammatory eyelid lesion. Biopsy was performed; histopathology and special staining confirmed a diagnosis of bacillary angiomatosis. The man was treated with oral erythromycin, and the lesion resolved. The etiologic agents of bacillary angiomatosis are Bartonella henselae and Bartonella quintana, Gram-negative coccobacilli. The organisms stain positively with the Warthin-Starry silver stain. Lesions can be cutaneous or visceral and have been commonly described in immunocompromised patients. Histopathologic examination of lesions reveals angiogenesis and cellular proliferation. Bacillary angiomatosis can be treated with oral antibiotics.

  3. Sådan bygger man en kvantecomputer

    DEFF Research Database (Denmark)

    Mølmer, Klaus

    2009-01-01

    KRONIK: Professor Klaus Mølmer forklarer, hvordan man kan konstruere en kvantecomputer. Det kræver en brudebuket, der både er der og ikke er der, og som kan kastes til alle gæsterne ved et bryllup på samme tid.......KRONIK: Professor Klaus Mølmer forklarer, hvordan man kan konstruere en kvantecomputer. Det kræver en brudebuket, der både er der og ikke er der, og som kan kastes til alle gæsterne ved et bryllup på samme tid....

  4. Quantum Man: Richard Feynman's Life in Science

    CERN Document Server

    CERN. Geneva

    2011-01-01

    It took a man who was willing to break all the rules to tame a theory that breaks all the rules. This talk will be based on my new book Quantum Man: Richard Feynman's life in science. I will try and present a scientific overview of the contributions of Richard Feynman, as seen through the arc of his fascinating life. From Quantum Mechanics to Antiparticles, from Rio de Janeiro to Los Alamos, a whirlwind tour will provide insights into the character, life and accomplishments of one of the 20th centuries most important scientists, and provide an object lesson in scientific integrity.

  5. Homo Tangens, or Man Touching and Tangible

    OpenAIRE

    J Mizinska

    2011-01-01

    The article is devoted to the analysis of the concept sense of touch, which is considered in all its aspects and dimensions. The author's aim is to determine what is touch in terms of philosophy, what types it has and what traditional functions (i.e. prior to the emergence of virtual reality) each of these functions performed. The conducted research allows the author to make a conclusion about the importance of perceiving the role and significance of man as a homo tangens - man touching and t...

  6. Homo Tangens, or Man Touching and Tangible

    Directory of Open Access Journals (Sweden)

    J Mizinska

    2011-09-01

    Full Text Available The article is devoted to the analysis of the concept sense of touch, which is considered in all its aspects and dimensions. The author's aim is to determine what is touch in terms of philosophy, what types it has and what traditional functions (i.e. prior to the emergence of virtual reality each of these functions performed. The conducted research allows the author to make a conclusion about the importance of perceiving the role and significance of man as a homo tangens - man touching and tangible.

  7. An integrable coupling family of Merola-Ragnisco-Tu lattice systems, its Hamiltonian structure and related nonisospectral integrable lattice family

    Energy Technology Data Exchange (ETDEWEB)

    Xu Xixiang, E-mail: xu_xixiang@hotmail.co [College of Science, Shandong University of Science and Technology, Qingdao, 266510 (China)

    2010-01-04

    An integrable coupling family of Merola-Ragnisco-Tu lattice systems is derived from a four-by-four matrix spectral problem. The Hamiltonian structure of the resulting integrable coupling family is established by the discrete variational identity. Each lattice system in the resulting integrable coupling family is proved to be integrable discrete Hamiltonian system in Liouville sense. Ultimately, a nonisospectral integrable lattice family associated with the resulting integrable lattice family is constructed through discrete zero curvature representation.

  8. Performance of the TU/e 2.6 Cell Rf-photogun in the 'Pancake' Regime

    NARCIS (Netherlands)

    Geer, van der S.B.; Loos, de M.J.; Luiten, O.J.; Brussaard, G.J.H.; Wiel, van der M.J.; Pöplau, G.

    2004-01-01

    The 2.6 cell rf-photogun currently in operation at Eindhoven University of Technology has been designed as a booster for a 2 MeV semi-DC accelerator with a field of 1 GV/m. In this paper we present GPT simulation results of the TU/e gun, operated without its pre-accelerator, in the low-charge

  9. Thermostability of Multidomain Proteins: Elongation Factors EF-Tu from Escherichia coli and Bacillus stearothermophilus and Their Chimeric Forms

    Czech Academy of Sciences Publication Activity Database

    Šanderová, Hana; Hůlková, Marta; Maloň, Petr; Kepková, M.; Jonák, Jiří

    2004-01-01

    Roč. 13, č. 1 (2004), s. 89-99 ISSN 0961-8368 R&D Projects: GA AV ČR IPP1050128; GA ČR GA204/98/0863; GA ČR GA303/02/0689 Institutional research plan: CEZ:AV0Z4055905; CEZ:AV0Z5052915 Keywords : elongation factor EF-Tu, thermostability, chimeric protein Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.116, year: 2004

  10. An integrable coupling family of Merola-Ragnisco-Tu lattice systems, its Hamiltonian structure and related nonisospectral integrable lattice family

    International Nuclear Information System (INIS)

    Xu Xixiang

    2010-01-01

    An integrable coupling family of Merola-Ragnisco-Tu lattice systems is derived from a four-by-four matrix spectral problem. The Hamiltonian structure of the resulting integrable coupling family is established by the discrete variational identity. Each lattice system in the resulting integrable coupling family is proved to be integrable discrete Hamiltonian system in Liouville sense. Ultimately, a nonisospectral integrable lattice family associated with the resulting integrable lattice family is constructed through discrete zero curvature representation.

  11. Behaviour of hormone parameters and equivalent iodide clearance (TcTu) on suppressive T4 treatment of enthyroid struma

    International Nuclear Information System (INIS)

    Greis, W.

    1978-01-01

    84 patients with euthyroid diffuse struma were stabilised at the individually necessary thyroxine dose by means of TcTU, T 4 , and NTR. As long-term medication, 100μg l-thyroxin were required in 143% of the patients, 150 μg in 83.3% of the patients, and 200 μg in 2.4% of the patients. After 8 to 12 weeks of therapy, the TcTU as an estimate of the iodide clearance was suppressed to 0.1 to 3.5 ( x +- s). T 4 and NTR values were near the upper limit of the normal at a normal T 3 level. After administration of 150 μg thyroxine per day for 12 weeks and 200μg thyroxine for 4 weeks, TcTU is suppressed to a comparable extent while the weaker suppressive effect of a 12 weeks' medication with 100μg thyroxine could not be improved even by a prolonged therapy. After one year of treatment, calculations of the thyroid surface in scintiscans showed a successful therapy in 82% of the patients while the circumference of the neck had become smaller only in 60% of the patients. Therapy was generally less successful in patients over 18 years of age. (orig.) [de

  12. On Being an Angry Black Man

    Science.gov (United States)

    Quaye, Stephen John

    2017-01-01

    Black men are often seen as problems, threats, and thugs. The mere existence of a Black body is often met with fear. Using autoethnographic mystory, I blend personal stories, poetry, song lyrics, and analysis to subvert the angry Black man mantra and explore the productive use of anger to stimulate change.

  13. Ergonomic ship brigde design supports minimum manning

    NARCIS (Netherlands)

    Punte, P.A.J.; Post, W.M.

    2001-01-01

    The Royal Netherlands Navy is planning to design a hydrographic survey vessel to replace the currently used vessels in order to extend the tasks of an Officer by reducing require manning. The design includes the arrangements of workspace and the detailed design of workplaces. Digital human models

  14. Plutonium in domestic animals and man

    International Nuclear Information System (INIS)

    Coughtrey, P.J.; Jackson, D.; Jones, C.H.; Kane, P.; Thorne, M.C.

    1984-01-01

    This chapter deals with plutonium adsorption, retention and translocation rates in lungs, the gastrointestinal tract, liver and in body tissues of domestic animals and man. Urinary and faecal excretion of plutonium is discussed. Transfer rates to eggs, milk, foetus and newborn are considered. Of all these subjects, data are presented extracted from literature and cast in tables

  15. Man-influenced vegetation of North Korea

    Czech Academy of Sciences Publication Activity Database

    Kolbek, Jiří; Jarolímek, I.

    2008-01-01

    Roč. 40, č. 1 (2008), s. 381-404 ISSN 0253-116X R&D Projects: GA ČR(CZ) GA206/05/0119 Institutional research plan: CEZ:AV0Z60050516 Keywords : vegetation classification * weed communities * man-depending vegetation Subject RIV: EF - Botanics

  16. [Albert Schweitzer. The man as a symbol].

    Science.gov (United States)

    Urdaneta-Carruyo, Eliexer

    2007-01-01

    Albert Schweitzer, the great missionary physician from the XXth century, had a versatile personality that integrated multiple talents, leading to the slightly frequent conjunction of the thinker with the man of action, and the humanist with the scientist and the artist. He studied all these disciplines in a brilliant manner: Philosophy, Theology, Music and Medicine; he was also a great scholar of Bach's work, Jesus Christ and the civilization history. In his maturity, this great man renounced to the fame and glory gained as intellectual and musician, to dedicate his life as a physician for the forgotten African natives. His deeply religious spirit allowed him to penetrate into the most recondite of the human soul; in his personality, he expressed in its entire dimension the eternally unsatisfied desire of the solitary man, against the immensity of the universe. His philosophy, based on the respect for life, was realized throughout the practice of the medical profession. His noble character and personality was based on the man as symbol, since it was not so much what he did helping people but what people could do to others due to him. His singular example represented a moral force in the world, superior to millions of men armed for a war. In 1953, he received the Nobel Peace Prize for his philanthropic work in Africa during more that fifty years, and for his deep love to the living beings. He was transformed in a perennial legend as the Lambaréné doctor.

  17. [Dipylidium caninum, a rare parasite in man].

    Science.gov (United States)

    Brandstetter, W; Auer, H

    1994-01-01

    Dipylidium caninum, the dog tapeworm, is a common cosmopolitan parasite of dogs and cats. Infestations of man are observed only sporadically. We report the case of a 22 months-old child living in Upper Austria with dipylidiasis. The parasite is briefly outlined with respect to biology, epidemiology, clinical features, diagnosis, therapy and prevention.

  18. The ancestry and affiliations of Kennewick Man

    DEFF Research Database (Denmark)

    Rasmussen, Morten; Sikora, Martin; Albrechtsen, Anders

    2015-01-01

    Kennewick Man, referred to as the Ancient One by Native Americans, is a male human skeleton discovered in Washington state (USA) in 1996 and initially radiocarbon dated to 8,340-9,200 calibrated years before present (BP). His population affinities have been the subject of scientific debate and le...

  19. Menkes' disease in Mottled mice and man

    International Nuclear Information System (INIS)

    Hamer, C.J.A. van den; Prins, H.W.; Nooijen, J.L.

    1979-01-01

    Biochemically the defect of the Brindled allelic mutant of the Mottled mouse and of Menkes' disease in man are very similar if not identical. A modification of a normal Cu-binding protein or an unrestrained synthesis of a Cu-binding protein that normally is present only in small amounts is proposed as the basis of this disease

  20. Man's Search: English, Mythology. 5112.22.

    Science.gov (United States)

    Gundersheimer, Lenore C.

    A course which is an exploration of man's eternal search to understand himself and his world through the study of the mythology of the world is presented. Performance objectives include: (1) Students will recognize the content of the myths studied; (2) Students will identify the specific characteristics of the civilization studied; (3) Students…

  1. The Language of Man. Book 6.

    Science.gov (United States)

    Littell, Joseph Fletcher, Ed.

    This textbook, book 6 of "The Language of Man" series, covers semantics, the language of politics, language and race, the language of advertising, and the origins and growth of the English language. The material analyzed comes from many sources (advertisements, newspaper articles, poems, parodies) and attempts to demonstrate the effect of the…

  2. Dosimetric system for prolonged manned flights

    International Nuclear Information System (INIS)

    Akatov, Yu.A.; Kovalev, E.E.; Sakovich, V.A.; Deme, Sh.; Fekher, I.; Nguen, V.D.

    1991-01-01

    Comments for the All-Union state standard 25645.202-83 named Radiation safety of a spacecraft crew during space flight. Requirements for personnel dosimetric control, are given. Devices for the dosimetric control used in manned space flights nowadays are reviewed. The performance principle and structure of the FEDOR dosimetric complex under development are discussed

  3. Genetic Engineering: The Modification of Man

    Science.gov (United States)

    Sinsheimer, Robert L.

    1970-01-01

    Describes somatic and genetic manipulations of individual genotypes, using diabetes control as an example of the first mode that is potentially realizable be derepression or viral transduction of genes. Advocates the use of genetic engineering of the second mode to remove man from his biological limitations, but offers maxims to ensure the…

  4. Elementary particles in the service of man

    CERN Multimedia

    1966-01-01

    This article was prepared by the Atomic Energy Research Establishment, Harwell, and the Rutherford Laboratory in the U.K., for a Physics Exhibition in March of this year and is reproduced here with acknowledgement. It is an account of how some of the knowledge gained in the previous generation of our research has already been applied 'in the service of man'.

  5. The effects of radiation on man

    International Nuclear Information System (INIS)

    Saunders, P.

    1981-01-01

    Available evidence on the effects of high levels of radiation on man and the predictions which have been made on possible low level effects, by extrapolation of the high level data, are summarised. The factors which influence the biological effects of radiation are examined and acute, delayed, somatic and hereditary effects as reported in the literature, are discussed. (U.K.)

  6. Man-machine communication at Forsmark 3

    International Nuclear Information System (INIS)

    Hultquist, Goeran; Norberg, Soeren

    1984-01-01

    The design of Forsmark 3 began in 1976 and the control room layout and equipment were discussed right from the start. Susequent evolution and events in other nuclear power plants have, however, radically changed the direction of the development of the man-machine functions. (author)

  7. Man, Technology and the Natural Holism.

    Science.gov (United States)

    Murthy, K. K.

    1980-01-01

    Indicates that the affluence brought about by the impact of science and technology on society now threatens mankind's further course. Asserts that the answer to this predicament lies neither with technological optimists nor with cultural pessimists, but in the resolution of basic value questions related to man's place in nature. (Author/GS)

  8. Estimator's electrical man-hour manual

    CERN Document Server

    Page, John S

    1999-01-01

    This manual's latest edition continues to be the best source available for making accurate, reliable man-hour estimates for electrical installation. This new edition is revised and expanded to include installation of electrical instrumentation, which is used in monitoring various process systems.

  9. Man machine interface and its implementation

    International Nuclear Information System (INIS)

    Hills, B.G.; Boettcher, D.B.; Reed, R.

    1992-01-01

    Sizewell B is the latest nuclear power station to be constructed in the United Kingdom: its Man-Machine Interfaces are therefore, by definition, the state-of-the-art. This paper discusses the principal Man-Machine Interfaces used in the operation of the station, and the systems that implement them. The Man-Machine Interface facilities discussed are: in the Main Control Room, which is used for normal operation and shutdown of the plant: in the Auxiliary Shutdown Room, which allows shutdown of the reactor if evacuation of the main Control Room is necessary: and in the Technical Support Centre, which is used for remote monitoring of the plant. The Man-Machine Interfaces that are described are parts of a station-wide group of interlinked computer systems called the Data Processing and Control System. This system collects data from the plant and displays it to the operators via discrete devices and on graphical computer displays. It also acquires control inputs from the operators via switches, which are then used to provide remote manual control, modulating control and sequence control. The computer system that handles the plant process data and alarm information displays uses a windowing interface with keyboard and trackerball navigation to allow easy retrieval and viewing of information. It is this system that is the main topic of this paper. (author)

  10. Emblem for the first manned Skylab mission

    Science.gov (United States)

    1972-01-01

    This is the emblem for the first manned Skylab mission. It wil be a mission of up to 28 days. The patch, designed by artist Kelly Freas, shows the Skylab silhouetted against the earth's globe, which in turn is eclipsing the Sun - showing the brilliant signet-ring pattern of the instant before total eclipse.

  11. Collaboration of the Dutch research program for radioactive waste disposal (OPERA) and TU Delft

    Energy Technology Data Exchange (ETDEWEB)

    Bykov, D.M.; Kloosterman, J.L. [TU Delft (Netherlands). Reactor Inst. Delft; Neeft, E.A.C.; Verhoef, E.V. [COVRA N.V., Nieuwdorp (Netherlands)

    2015-07-01

    awarded research proposals available at www.covra.nl/downloads/o pera. Building up competences and knowledge on radioactive waste management and geological disposal is an important goal of OPERA. To this end OPERA collaborates with TU Delft to develop an academic curriculum for the chair Chemistry of the Nuclear Fuel Cycle in the Master of Science Engineering. Furthermore, the results obtained in OPERA will be presented at a Summer School which is planned to be organized at the end of the Program. TU Delft educates young specialists, bachelor and master students, by research projects on geological disposal at the new actinide laboratory (U and Th). For such purpose the knowledge transfer from other OPERA partners is also foreseen, including students internships and visits of the research facilities. Reactor Institute Delft (RID) is part of the Applied Sciences faculty of TU Delft and houses the Radiation Science and Technology (RST) department. RID operates the Hoger Onderwijs Reactor (HOR), a 2 MW pool- type research reactor in an academic setting. The reactor is used as a source of neutrons and positrons for research purposes, including those of OPERA. It also provides neutrons to a variety of facilities for radioisotope production and neutron activation analysis. OPERA is financed by the Dutch Ministry of Economic Affairs and the public limited liability company Elektriciteits-Produktiemaatschappij Zuid-Nederland (EPZ) and coordinated by COVRA.

  12. Collaboration of the Dutch research program for radioactive waste disposal (OPERA) and TU Delft

    International Nuclear Information System (INIS)

    Bykov, D.M.; Kloosterman, J.L.

    2015-01-01

    awarded research proposals available at www.covra.nl/downloads/o pera. Building up competences and knowledge on radioactive waste management and geological disposal is an important goal of OPERA. To this end OPERA collaborates with TU Delft to develop an academic curriculum for the chair Chemistry of the Nuclear Fuel Cycle in the Master of Science Engineering. Furthermore, the results obtained in OPERA will be presented at a Summer School which is planned to be organized at the end of the Program. TU Delft educates young specialists, bachelor and master students, by research projects on geological disposal at the new actinide laboratory (U and Th). For such purpose the knowledge transfer from other OPERA partners is also foreseen, including students internships and visits of the research facilities. Reactor Institute Delft (RID) is part of the Applied Sciences faculty of TU Delft and houses the Radiation Science and Technology (RST) department. RID operates the Hoger Onderwijs Reactor (HOR), a 2 MW pool- type research reactor in an academic setting. The reactor is used as a source of neutrons and positrons for research purposes, including those of OPERA. It also provides neutrons to a variety of facilities for radioisotope production and neutron activation analysis. OPERA is financed by the Dutch Ministry of Economic Affairs and the public limited liability company Elektriciteits-Produktiemaatschappij Zuid-Nederland (EPZ) and coordinated by COVRA.

  13. Development of SAP-DoA techniques for GPR data processing within COST Action TU1208

    Science.gov (United States)

    Meschino, Simone; Pajewski, Lara; Marciniak, Marian

    2016-04-01

    This work focuses on the use of Sub-Array Processing (SAP) and Direction of Arrival (DoA) approaches for the processing of Ground-Penetrating Radar data, with the purpose of locating metal scatterers embedded in concrete or buried in the ground. Research activities have been carried out during two Short-Term Scientific Missions (STSMs) funded by the COST (European COoperation in Science and Technology) Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar" in May 2015 and January 2016. In applications involving smart antennas and in the presence of several transmitters operating simultaneously, it is important for a receiving array to be able to estimate the Direction of Arrival (DoA) of the incoming signals, in order to decipher how many emitters are present and predict their positions. A number of methods have been devised for DoA estimation: the MUltiple SIgnal Classification (MUSIC) and Estimation of Signal Parameters via Rotational Invariance Technique (ESPRIT) are amongst the most popular ones [1]. In the scenario considered by us, the electromagnetic sources are the currents induced on metal elements embedded in concrete or buried in the ground. GPR radargrams are processed, to estimate the DoAs of the electric field back-scattered by the sought targets. In order to work in near-field conditions, a sub-array processing (SAP) approach is adopted: the radargram is partitioned in sub-radargrams composed of few A-scans each, the dominant DoA is predicted for each sub-radargram. The estimated angles are triangulated, obtaining a set of crossings with intersections condensed around object locations. This pattern is filtered, in order to remove a noisy background of unwanted crossings, and is processed by applying the statistical procedure described in [2]. We tested our approach on synthetic GPR radargrams, obtained by using the freeware simulator gprMax implementing the Finite-Difference Time-Domain method [3]. In particular, we worked with

  14. From the rights of man to the human rights: Man - nation - humanity

    Directory of Open Access Journals (Sweden)

    Zaharijević Adriana

    2008-01-01

    Full Text Available The insistence on the fact that human rights and the rights of man (codified in The Universal Declaration of Human Rights and Declaration of the Rights of Man and of the Citizen, respectively are not one and the same, which could be deduced from the notion of man common to both terms, is the key thesis of this text. By developing this motive, I try to determine the following: that the notion of man, by definition inclusive and abstractly non-discriminative term, is in fact established on tacit exclusions in the time of its inception (Enlightenment revolutinary era, and it was only upon these exclusions that the term man could have signified "the free and equal". Although the parallel or simultaneous evolution and implementation of the rights of man and national rights might seem contradictory, I seek to demonstrate that this paradox is only ostensible, arguing that the notion of man is itself limited and exclusionary, and is therefore compatible with the exclusivity which is the conditio sine qua non of nation. The consequences of nationalism - World Wars, primarily - proved that the conception of liberty and equality, based on the conception of fraternity of men (white European males, and of partial democracy pretending to be universal, cannot be maintained any further. Codification of universal human rights represents a reaction to this internal discrepancy inasmuch as it is a reaction to the destructiveness of all kinds of nationalisms. The notion of life, developed in this text, corresponds to the fundamental requirement for the right to life (as the first and the most basic of all human rights, which no longer belongs to "man", but to everyone.

  15. "TuNa-saving" endoscopic medial maxillectomy: a surgical technique for maxillary inverted papilloma.

    Science.gov (United States)

    Pagella, Fabio; Pusateri, Alessandro; Matti, Elina; Avato, Irene; Zaccari, Dario; Emanuelli, Enzo; Volo, Tiziana; Cazzador, Diego; Citraro, Leonardo; Ricci, Giampiero; Tomacelli, Giovanni Leo

    2017-07-01

    The maxillary sinus is the most common site of sinonasal inverted papilloma. Endoscopic sinus surgery, in particular endoscopic medial maxillectomy, is currently the gold standard for treatment of maxillary sinus papilloma. Although a common technique, complications such as stenosis of the lacrimal pathway and consequent development of epiphora are still possible. To avoid these problems, we propose a modification of this surgical technique that preserves the head of the inferior turbinate and the nasolacrimal duct. A retrospective analysis was performed on patients treated for maxillary inverted papilloma in three tertiary medical centres between 2006 and 2014. Pedicle-oriented endoscopic surgery principles were applied and, in select cases where the tumour pedicle was located on the anterior wall, a modified endoscopic medial maxillectomy was carried out as described in this paper. From 2006 to 2014 a total of 84 patients were treated. A standard endoscopic medial maxillectomy was performed in 55 patients (65.4%), while the remaining 29 (34.6%) had a modified technique performed. Three recurrences (3/84; 3.6%) were observed after a minimum follow-up of 24 months. A new surgical approach for select cases of maxillary sinus inverted papilloma is proposed in this paper. In this technique, the endoscopic medial maxillectomy was performed while preserving the head of the inferior turbinate and the nasolacrimal duct ("TuNa-saving"). This technique allowed for good visualization of the maxillary sinus, good oncological control and a reduction in the rate of complications.

  16. DeitY-TU face database: its design, multiple camera capturing, characteristics, and evaluation

    Science.gov (United States)

    Bhowmik, Mrinal Kanti; Saha, Kankan; Saha, Priya; Bhattacharjee, Debotosh

    2014-10-01

    The development of the latest face databases is providing researchers different and realistic problems that play an important role in the development of efficient algorithms for solving the difficulties during automatic recognition of human faces. This paper presents the creation of a new visual face database, named the Department of Electronics and Information Technology-Tripura University (DeitY-TU) face database. It contains face images of 524 persons belonging to different nontribes and Mongolian tribes of north-east India, with their anthropometric measurements for identification. Database images are captured within a room with controlled variations in illumination, expression, and pose along with variability in age, gender, accessories, make-up, and partial occlusion. Each image contains the combined primary challenges of face recognition, i.e., illumination, expression, and pose. This database also represents some new features: soft biometric traits such as mole, freckle, scar, etc., and facial anthropometric variations that may be helpful for researchers for biometric recognition. It also gives an equivalent study of the existing two-dimensional face image databases. The database has been tested using two baseline algorithms: linear discriminant analysis and principal component analysis, which may be used by other researchers as the control algorithm performance score.

  17. Electromagnetic simulators for Ground Penetrating Radar applications developed in COST Action TU1208

    Science.gov (United States)

    Pajewski, Lara; Giannopoulos, Antonios; Warren, Craig; Antonijevic, Sinisa; Doric, Vicko; Poljak, Dragan

    2017-04-01

    Founded in 1971, COST (European COoperation in Science and Technology) is the first and widest European framework for the transnational coordination of research activities. It operates through Actions, science and technology networks with a duration of four years. The main objective of the COST Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar" (4 April 2013 - 3 October 2017) is to exchange and increase knowledge and experience on Ground-Penetrating Radar (GPR) techniques in civil engineering, whilst promoting in Europe a wider use of this technique. Research activities carried out in TU1208 include all aspects of the GPR technology and methodology: design, realization and testing of radar systems and antennas; development and testing of surveying procedures for the monitoring and inspection of structures; integration of GPR with other non-destructive testing approaches; advancement of electromagnetic-modelling, inversion and data-processing techniques for radargram analysis and interpretation. GPR radargrams often have no resemblance to the subsurface or structures over which the profiles were recorded. Various factors, including the innate design of the survey equipment and the complexity of electromagnetic propagation in composite scenarios, can disguise complex structures recorded on reflection profiles. Electromagnetic simulators can help to understand how target structures get translated into radargrams. They can show the limitations of GPR technique, highlight its capabilities, and support the user in understanding where and in what environment GPR can be effectively used. Furthermore, electromagnetic modelling can aid the choice of the most proper GPR equipment for a survey, facilitate the interpretation of complex datasets and be used for the design of new antennas. Electromagnetic simulators can be employed to produce synthetic radargrams with the purposes of testing new data-processing, imaging and inversion algorithms, or assess

  18. Understanding and modelling Man-Machine Interaction

    International Nuclear Information System (INIS)

    Cacciabue, P.C.

    1991-01-01

    This paper gives an overview of the current state of the art in man machine systems interaction studies, focusing on the problems derived from highly automated working environments and the role of humans in the control loop. In particular, it is argued that there is a need for sound approaches to design and analysis of Man-Machine Interaction (MMI), which stem from the contribution of three expertises in interfacing domains, namely engineering, computer science and psychology: engineering for understanding and modelling plants and their material and energy conservation principles; psychology for understanding and modelling humans and their cognitive behaviours; computer science for converting models in sound simulations running in appropriate computer architectures. (author)

  19. The Somerton man : an unsolved history

    Directory of Open Access Journals (Sweden)

    Balint, Ruth

    2010-01-01

    Full Text Available The case of the unknown man who died mysteriously at Somerton Beach in South Australia in 1948 remains an open police investigation, although the trail today has grown fairly cold. Revisiting the case, and the responses the mystery of his person have elicited, enables a special historical insight into Australia’s postwar society, and the ways in which the past is continually reshaped by the subjectivities of the present. Further, an unsolved case such as this provides for a unique kind of historical project. The limitations of a history without a coherent centre are myriad, yet so are the possibilities. In this article, I explore the possibilities of an ‘unsolved history’, a history of dead ends, and argue that it is the very unknowable-ness of the Somerton Man that allows for a perception of history as multi-dimensional and complex.

  20. The Somerton Man: An Unsolved History

    Directory of Open Access Journals (Sweden)

    Ruth Balint

    2010-09-01

    Full Text Available The case of the unknown man who died mysteriously at Somerton Beach in South Australia in 1948 remains an open police investigation, although the trail today has grown fairly cold. Revisiting the case, and the responses the mystery of his person have elicited, enables a special historical insight into Australia’s postwar society, and the ways in which the past is continually reshaped by the subjectivities of the present. Further, an unsolved case such as this provides for a unique kind of historical project. The limitations of a history without a coherent centre are myriad, yet so are the possibilities.  In this article, I explore the possibilities of an ‘unsolved history’, a history of dead ends, and argue that it is the very unknowable-ness of the Somerton Man that allows for a perception of history as multi-dimensional and complex.

  1. Recent developments in man-machine systems

    International Nuclear Information System (INIS)

    Johannsen, G.

    1987-01-01

    The field of man-machine systems is introduced with its subareas and a short outline of its history of 45 years. Three current lines of development in university and industrial research are emphasized. Today, the human problem solving activities are experimentally investigated and analytically described more vigorously than the control activities. Further, improved information presentations and decision support are made possible through new technologies of computer graphics and expert systems. At last, work on a general design methodology for man-machine systems is in progress. The aim is to better support human operators of dynamic technological systems as well as designers of graphics for visual display units and of dialogue styles. Thereby, safety and availability of the complete system can be increased. (orig.) [de

  2. Understanding and modelling man-machine interaction

    International Nuclear Information System (INIS)

    Cacciabue, P.C.

    1996-01-01

    This paper gives an overview of the current state of the art in man-machine system interaction studies, focusing on the problems derived from highly automated working environments and the role of humans in the control loop. In particular, it is argued that there is a need for sound approaches to the design and analysis of man-machine interaction (MMI), which stem from the contribution of three expertises in interfacing domains, namely engineering, computer science and psychology: engineering for understanding and modelling plants and their material and energy conservation principles; psychology for understanding and modelling humans an their cognitive behaviours; computer science for converting models in sound simulations running in appropriate computer architectures. (orig.)

  3. [Man's place and anthropology in bioethics].

    Science.gov (United States)

    Tomar Romero, Francisca

    2013-01-01

    From the analysis of its epistemological status, the article focuses on the philosophical fundament of bioethics, stressing the need for an authentic anthropology as a reference or starting point. Being an applied ethics, the first fundament of bioethics is in ethics. It shows how only personalistic ethics, which takes as reference the nature or essence of man, can offer objective and universal criteria. Philosophical anthropology studies man as a whole, in an integral manner, from the perspective of its nature or fundamental aspects of his being. It analyzes the distinction and relationship between the philosophical anthropology and the positive anthropologies, as well as with the physical, human and social sciences. Finally, it reflects on the current anthropological crisis and its ethical consequences.

  4. Man-midwifery history: 1730-1930.

    Science.gov (United States)

    Shelton, D C

    2012-11-01

    This paper seeks to determine whether the man-midwives William Smellie and William Hunter deserve continuing approbation as 'Founding Fathers' of the obstetrics profession. Scrutiny of their careers reveals their involvement in murders for dissection. In addition, the man-midwifery initiative of delivery in lying-in hospitals resulted in around 1 million more deaths in Britain and Ireland between 1730 and 1930, than would have occurred had home-births remained as the norm. While some may still credit Smellie and Hunter with obstetric discoveries, their knowledge was obtained by murder-for-dissection. That indictment, together with the lying-in hospital legacy, far outweighs their discoveries. The paper invites further constructive discussion and debate, but concludes the accolade of Founding Fathers is undeserved. Any continuing endorsement of Smellie and Hunter effectively demeans the high ethical standards and reputation of current obstetric professionals.

  5. The shipping man adventures in ship finance

    CERN Document Server

    McCleery, Matthew

    2013-01-01

    When restless New York City hedge fund manager Robert Fairchild watches the Baltic Dry Cargo Index plunge 97%, registering an all-time high and a 25-year low within the span of just six months, he decides to buy a ship. Immediately fantasizing about naming a vessel after his wife, carrying a string of worry beads and being able to introduce himself as a "shipowner" at his upcoming college reunion, Fairchild immediately embarks on an odyssey into the most exclusive, glamorous and high stakes business in the world. From pirates off the coast of Somalia and on Wall Street to Greek and Norwegian shipping magnates, the education of Robert Fairchild is an expensive one. In the end, he loses his hedge fund, but he gains a life - as a Shipping Man. Part fast paced financial thriller, part ship finance text book, The Shipping Man is 310 pages of required reading for anyone with an interest in capital formation for shipping.

  6. The Somerton Man: An Unsolved History

    OpenAIRE

    Balint, Ruth

    2010-01-01

    The case of the unknown man who died mysteriously at Somerton Beach in South Australia in 1948 remains an open police investigation, although the trail today has grown fairly cold. Revisiting the case, and the responses the mystery of his person have elicited, enables a special historical insight into Australia’s postwar society, and the ways in which the past is continually reshaped by the subjectivities of the present. Further, an unsolved case such as this provides for a unique kind ...

  7. Don’t Trust the Big Man

    Science.gov (United States)

    2008-06-06

    on the scholar questioned, these entities began as either natural alliances of people already united by colocation, culture , ethnicity, religion and...anger to provide a channel for the pent-up anger at a failing government. This is where the tribal culture becomes interesting. The Big Man can find...Zulu, Dinka, and Maasai; the Shona and Yoruba and Somali - militates against the very idea of borders drawn through tribal and nomadic areas by the

  8. Bobby Fong: Man on a Mission

    Science.gov (United States)

    Fong, Colin

    2014-01-01

    Bobby Fong, was president of Ursinus College until his death in September 2014 and is the only person to have served twice as chair of the AAC&U Board of Directors. In this article, his son Collin presents remarks made at the memorial service for his father. Collin describes his father as a man with a mission, and that mission was to make the…

  9. Project Mercury: NASA's first manned space programme

    Science.gov (United States)

    Catchpole, John

    Project Mercury will offer a developmental resume of the first American manned spaceflight programme and its associated infrastructure, including accounts of space launch vehicles. The book highlights the differences in Redstone/Atlas technology, drawing similar comparisons between ballistic capsules and alternative types of spacecraft. The book also covers astronaut selection and training, as well as tracking systems, flight control, basic principles of spaceflight and detailed accounts of individual flights.

  10. The conception of man in Honorio Delgado

    OpenAIRE

    Chiappo, Leopoldo

    1992-01-01

    ​Honorio Delgado is still the most eminent authority in the history of psychiatric and psychopathological study in Peru and the spanish-speaking world. This article is an attempt to extract from the multi-faceted work of Honorario Delgado, not only in psychiatry, psychopathology, psychology, neurology, biology, ecology and medicine, bu also in philosophy, education, literary and biographical studies, and humanities as a whole, what one might call the “honorian” vision of the man, the explicit...

  11. Design of man-machine-communication-systems

    International Nuclear Information System (INIS)

    Zimmermann, R.

    1975-04-01

    This paper shows some fundamentals of man-machine-communication and deduces demands and recommendations for the design of communication systems. The main points are the directives for the design of optic display systems with details for visual perception and resolution, luminance and contrast, as well as discernibility and coding of displayed information. The most important rules are recommendations for acoustic information systems, control devices and for design of consoles are also given. (orig.) [de

  12. 2.1 Man: subject of protection

    International Nuclear Information System (INIS)

    2004-01-01

    This second chapter 'Man and environment' of the 7th state of the environment report of Austria describes the current situation of the protection of human health in terms of the European environmental policy and the main subjects of high relevance to it, such as air pollutants, water pollution, noise pollution, dangerous chemicals, food contamination, radiation protection, effects of climate change, plants, animal and habitats. (nevyjel)

  13. The Manned Spacecraft Center and medical technology

    Science.gov (United States)

    Johnston, R. S.; Pool, S. L.

    1974-01-01

    A number of medically oriented research and hardware development programs in support of manned space flights have been sponsored by NASA. Blood pressure measuring systems for use in spacecraft are considered. In some cases, complete new bioinstrumentation systems were necessary to accomplish a specific physiological study. Plans for medical research during the Skylab program are discussed along with general questions regarding space-borne health service systems and details concerning the Health Services Support Control Center.

  14. The Man-in-the-Middle Defence

    Science.gov (United States)

    Anderson, Ross; Bond, Mike

    Eliminating middlemen from security protocols helps less than one would think. EMV electronic payments, for example, can be made fairer by adding an electronic attorney - a middleman which mediates access to a customer’s card. We compare middlemen in crypto protocols and APIs with those in the real world, and show that a man-in-the-middle defence is helpful in many circumstances. We suggest that the middleman has been unfairly demonised.

  15. Malaysia : the lucky man of Asia?

    OpenAIRE

    Kind, Hans Jarle; Ismail, Mohd Nazari

    2001-01-01

    Malaysia has been labelled the Lucky Man of Asia due to its wealth of natural resources, such as tin, rubber, palm oil, pepper, tropical timber, petroleum and a very fertile soil. There is no doubt that this richness has helped Malaysia to achieve impressive growth rates over the last decades, but history has taught us that large endowments of natural resources by far are sufficient to generate development. Since the early 1970s Malaysia has led a relatively successful racial integration poli...

  16. Rodent management: the man/environment interface

    International Nuclear Information System (INIS)

    Jackson, W.B.

    1978-01-01

    Rodents which interact with man generally are regarded as undesirable. Attempts at eliminating such rodents by increasing predation (including traps, microbiological agents, toxicants) have been relatively unsuccessful. Management by environmental manipulation must be basic. This then can be supplemented with predation at critical points where public health, use practices, or imperfections in the system demand. Society mores, practices, and economic considerations also have significant impact on the management system

  17. Magnetic field and its influence on man

    International Nuclear Information System (INIS)

    Golovin, N.I.; Kurik, M.V.

    2001-01-01

    Positive effects of the Earth magnetic field (MF) on bacteria and animals are demonstrated. The same beneficial effect was found for man: screening of MF leads to blood vessel contraction and violation of exchange processes in organism. Effects of MF are considered as similar to that of catalysts. A correlation between MF values and various human diseases was found. Different methods of magnetotherapy are proposed

  18. Man-machine interface requirements - advanced technology

    Science.gov (United States)

    Remington, R. W.; Wiener, E. L.

    1984-01-01

    Research issues and areas are identified where increased understanding of the human operator and the interaction between the operator and the avionics could lead to improvements in the performance of current and proposed helicopters. Both current and advanced helicopter systems and avionics are considered. Areas critical to man-machine interface requirements include: (1) artificial intelligence; (2) visual displays; (3) voice technology; (4) cockpit integration; and (5) pilot work loads and performance.

  19. The effects of ionizing radiation on man

    International Nuclear Information System (INIS)

    Watson, G.M.

    1975-08-01

    This paper describes the major effects of ionizing radiation on man and the relationship between such effects and radiation dose, with the conclusion that standards of radiological safety must be based on the carcinogenetic and mutagenic properties of ionizing radiation. Man is exposed to radiation from natural sources and from man-made sources. Exposure from the latter should be regulated but, since there is little observational or experimental evidence for predicting the effects of the very small doses likely to be required for adequate standards of safety, it is necessary to infer them from what is seen at high doses. Because the formal relationship between dose and effect is not fully understood, simplifying assumptions are necessary to estimate the effects of low doses. Two such assumptions are conventionally used; that there is a linear relationship between dose and effect at all levels of dose, and that the rate at which a dose of radiation is given does not alter the magnitude of the effect. These assumptions are thought to be conservative, that is they will not lead to an underestimation of the effects of small radiation doses although they may give an over-estimate. (author)

  20. Man-machine interface for the MFTF

    International Nuclear Information System (INIS)

    Speckert, G.C.

    1979-01-01

    In any complex system, the interesting problems occur at the interface of dissimilar subsystems. Control of the Mirror Fusion Test Facility (MFTF) begins with the US Congress, which controls the dollars, which control the people, who control the nine top-level minicomputers, which control the 65 microprocessors, which control the hardware that controls the physics experiment. There are many interesting boundaries across which control must pass, and the one that this paper addresses is the man-machine one. For the MFTF, the man-machine interface consists of a system of seven control consoles, each allowing one operator to communicate with one minicomputer. These consoles are arranged in a hierarchical manner, and both hardware and software were designed in a top-down fashion. This paper describes the requirements and the design of the console system as a whole, as well as the design and operation of the hardware and software of each console, and examines the possible form of a future man-machine interface

  1. Pathways of evolution for man and machine

    Science.gov (United States)

    Mclaughlin, W. I.

    1983-01-01

    A simplified model of the future is introduced in order to examine the relations between man, machine, and extraterrestrial intelligence. The observed lack of extraterrestrials on earth is used as a boundary condition for the model. Two exobiological conclusions are obtained: (1) advanced extraterrestrials exist but are difficult to observe or to distinguish from natural phenomena, (2) lower level, man-like extraterrestrials, which are potentially observable, are rare in the Universe because they are rapidly replaced in the evolutinary sequence by the intelligent machines which they create. The decline of man is inferred and may take place as soon as 100 years from now or as long as 100,000 years from the present time. Thus, we are a short-lived species, having a life expectancy of only a million years. A note is appended on the rationale and methods of the search for extraterrestrial intelligence in light of the above calculations. The Tau Ceti and Epsilon Eridani systems present favourable opportunities for a radio-search experiment in 1987 and 1988, respectively.

  2. Man-machine interface for the MFTF

    Energy Technology Data Exchange (ETDEWEB)

    Speckert, G.C.

    1979-11-09

    In any complex system, the interesting problems occur at the interface of dissimilar subsystems. Control of the Mirror Fusion Test Facility (MFTF) begins with the US Congress, which controls the dollars, which control the people, who control the nine top-level minicomputers, which control the 65 microprocessors, which control the hardware that controls the physics experiment. There are many interesting boundaries across which control must pass, and the one that this paper addresses is the man-machine one. For the MFTF, the man-machine interface consists of a system of seven control consoles, each allowing one operator to communicate with one minicomputer. These consoles are arranged in a hierarchical manner, and both hardware and software were designed in a top-down fashion. This paper describes the requirements and the design of the console system as a whole, as well as the design and operation of the hardware and software of each console, and examines the possible form of a future man-machine interface.

  3. Manned spaceflight log II—2006–2012

    CERN Document Server

    Shayler, David J

    2013-01-01

    April 12, 1961 "Attention! This is Radio Moscow speaking...The world's first satellite spaceship, Vostock, with a man aboard, was put into orbit round the Earth." Soviet Union cosmonaut Yuri A. Gagarin becomes the first person to fly in space, completing one orbit in 108 minutes. April 5, 2001 As NASA prepares to fly the final Shuttle missions to the International Space Station, Russia launches Soyuz TMA 21 (code-named 'Yuri Gagarin') with the 28th ISS Expedition crew aboard, celebrating 50 years of manned spaceflight. Meanwhile, in China, preparations continue for launching the nation's first Space Station (called Tiangong 1 - or Heavenly Palace 1) later in the year. The sixth decade of manned spaceflight orbital operations has truly began. At this point in the history of human space exploration, it is timely to review the first five decades of adventure and look forward to the next decade and what it might bring. Several notable anniversaries celebrated in 2011 make it the right time to reflect and pay homa...

  4. Man in the middle attacks on SSL/TLS

    OpenAIRE

    Caro Alonso-Rodríguez, Antonio Jesús

    2013-01-01

    El proyecto estudia un tipo concreto de ataque sobre el protocolo SSL/TLS llamado "Man in the middle". El projecte estudia un tipus concret d'atac sobre el protocol SSL/TLS anomenat "Man in the middle".

  5. 29 CFR 780.305 - 500 man-day provision.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false 500 man-day provision. 780.305 Section 780.305 Labor...) Statutory Provisions § 780.305 500 man-day provision. (a) Section 3(u) of the Act defines man-day to mean “any day during which an employee performs agricultural labor for not less than 1 hour.” 500 man-days...

  6. Effector region of the translation elongation factor EF-Tu.GTP complex stabilizes an orthoester acid intermediate structure of aminoacyl-tRNA in a ternary complex.

    Science.gov (United States)

    Förster, C; Limmer, S; Zeidler, W; Sprinzl, M

    1994-01-01

    tRNA(Val) from Escherichia coli was aminoacylated with [1-13C]valine and its complex with Thermus thermophilus elongation factor EF-Tu.GTP was analyzed by 13C NMR spectroscopy. The results suggest that the aminoacyl residue of the valyl-tRNA in ternary complex with bacterial EF-Tu and GTP is not attached to tRNA by a regular ester bond to either a 2'- or 3'-hydroxyl group; instead, an intermediate orthoester acid structure with covalent linkage to both vicinal hydroxyls of the terminal adenosine-76 is formed. Mutation of arginine-59 located in the effector region of EF-Tu, a conserved residue in protein elongation factors and the alpha subunits of heterotrimeric guanine nucleotide-binding regulatory proteins (G proteins), abolishes the stabilization of the orthoester acid structure of aminoacyl-tRNA. PMID:8183898

  7. TaxMan: a taxonomic database manager

    Directory of Open Access Journals (Sweden)

    Blaxter Mark

    2006-12-01

    Full Text Available Abstract Background Phylogenetic analysis of large, multiple-gene datasets, assembled from public sequence databases, is rapidly becoming a popular way to approach difficult phylogenetic problems. Supermatrices (concatenated multiple sequence alignments of multiple genes can yield more phylogenetic signal than individual genes. However, manually assembling such datasets for a large taxonomic group is time-consuming and error-prone. Additionally, sequence curation, alignment and assessment of the results of phylogenetic analysis are made particularly difficult by the potential for a given gene in a given species to be unrepresented, or to be represented by multiple or partial sequences. We have developed a software package, TaxMan, that largely automates the processes of sequence acquisition, consensus building, alignment and taxon selection to facilitate this type of phylogenetic study. Results TaxMan uses freely available tools to allow rapid assembly, storage and analysis of large, aligned DNA and protein sequence datasets for user-defined sets of species and genes. The user provides GenBank format files and a list of gene names and synonyms for the loci to analyse. Sequences are extracted from the GenBank files on the basis of annotation and sequence similarity. Consensus sequences are built automatically. Alignment is carried out (where possible, at the protein level and aligned sequences are stored in a database. TaxMan can automatically determine the best subset of taxa to examine phylogeny at a given taxonomic level. By using the stored aligned sequences, large concatenated multiple sequence alignments can be generated rapidly for a subset and output in analysis-ready file formats. Trees resulting from phylogenetic analysis can be stored and compared with a reference taxonomy. Conclusion TaxMan allows rapid automated assembly of a multigene datasets of aligned sequences for large taxonomic groups. By extracting sequences on the basis of

  8. 29 CFR 780.317 - Man-day exclusion.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Man-day exclusion. 780.317 Section 780.317 Labor...) Statutory Provisions § 780.317 Man-day exclusion. Section 3(e)(2) specifically excludes from the employer's man-day total (as defined in section 3(u)) employees who qualify for exemption under section 13(a)(6...

  9. 29 CFR 780.309 - Man-day exclusion.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Man-day exclusion. 780.309 Section 780.309 Labor...) Statutory Provisions § 780.309 Man-day exclusion. Section 3(e)(1) specifically excludes from the employer's man-day total (as defined in section 3(u)) employees who qualify for exemption under section 13(a)(6...

  10. The Modern Igbo Man and Quest for Freedom | Ogugua | AFRREV ...

    African Journals Online (AJOL)

    The modern Igbo man has through the decades been beset with one type of problem or the other. He has known multi-quam problems: poverty, ignorance, marginalization, genocide, betrayal, war etc. It is the onus of this paper to examine our operative concepts, Igbo man.s set of unfreedoms, and the shades of Igboman.s ...

  11. Plasmodium Infection In Man: A Review | Ekpenyong | Animal ...

    African Journals Online (AJOL)

    Plasmodium infection in man is caused by the bite of an infected female Anopheles mosquito. This results in the disease, malaria. Malaria has serious debilitating effects on man. It adversely affectsman's health, strength and productivity. Here, a review of Plasmodium infection in man including the life cycle transmisson, ...

  12. 32 CFR 707.2 - Man overboard lights.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Man overboard lights. 707.2 Section 707.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY NAVIGATION SPECIAL RULES WITH RESPECT TO ADDITIONAL STATION AND SIGNAL LIGHTS § 707.2 Man overboard lights. Naval vessels may display, as a means of indicating man overboard, two...

  13. Man bhawan - new chrysanthemum cultivar induced by gamma irradiation

    International Nuclear Information System (INIS)

    Datta, S.K.

    1987-01-01

    Attempts were made to find out the biochemical difference between two gamma ray induced chrysanthemum cultivars, 'Flirt' and 'Man Bhawan' by thin layer chromatographic and spectrophotometric analysis of pigments. The analysis were done from florets extracts of original cv., 'Flirt' and mutant 'Man Bhawan' at full bloom stage and also at fading of 'Man Bhawan'. (author)

  14. Man-systems distributed system for Space Station Freedom

    Science.gov (United States)

    Lewis, J. L.

    1990-01-01

    Viewgraphs on man-systems distributed system for Space Station Freedom are presented. Topics addressed include: description of man-systems (definition, requirements, scope, subsystems, and topologies); implementation (approach, tools); man-systems interfaces (system to element and system to system); prime/supporting development relationship; selected accomplishments; and technical challenges.

  15. Grounding the RPA Force: Why Machine Needs Man

    Science.gov (United States)

    2016-06-01

    AU/ACSC/2016 AIR COMMAND AND STAFF COLLEGE AIR UNIVERSITY GROUNDING THE RPA FORCE: WHY MACHINE NEEDS MAN by Charles M. Washuk, Major, USAF (MBA...6 CHALLENGES OF MANNED FLIGHT...tactics will still require the presence of an operator, or “ man .” This paper focuses on the need for the Air Force to address the 18X career field and

  16. The Ideal Man and Woman According to University Students

    Science.gov (United States)

    Weinstein, Lawrence; Laverghetta, Antonio V.; Peterson, Scott A.

    2009-01-01

    The present study determined if the ideal man has changed over the years and who and what the ideal woman is. We asked students at Cameron University to rate the importance of character traits that define the ideal man and woman. Subjects also provided examples of famous people exemplifying the ideal, good, average, and inferior man and woman. We…

  17. Elongation Factor Tu and Heat Shock Protein 70 Are Membrane-Associated Proteins from Mycoplasma ovipneumoniae Capable of Inducing Strong Immune Response in Mice.

    Directory of Open Access Journals (Sweden)

    Fei Jiang

    Full Text Available Chronic non-progressive pneumonia, a disease that has become a worldwide epidemic has caused considerable loss to sheep industry. Mycoplasma ovipneumoniae (M. ovipneumoniae is the causative agent of interstitial pneumonia in sheep, goat and bighorn. We here have identified by immunogold and immunoblotting that elongation factor Tu (EF-Tu and heat shock protein 70 (HSP 70 are membrane-associated proteins on M. ovipneumonaiea. We have evaluated the humoral and cellular immune responses in vivo by immunizing BALB/c mice with both purified recombinant proteins rEF-Tu and rHSP70. The sera of both rEF-Tu and rHSP70 treated BALB/c mice demonstrated increased levels of IgG, IFN-γ, TNF-α, IL-12(p70, IL-4, IL-5 and IL-6. In addition, ELISPOT assay showed significant increase in IFN-γ+ secreting lymphocytes in the rHSP70 group when compared to other groups. Collectively our study reveals that rHSP70 induces a significantly better cellular immune response in mice, and may act as a Th1 cytokine-like adjuvant in immune response induction. Finally, growth inhibition test (GIT of M. ovipneumoniae strain Y98 showed that sera from rHSP70 or rEF-Tu-immunized mice inhibited in vitro growth of M. ovipneumoniae. Our data strongly suggest that EF-Tu and HSP70 of M. ovipneumoniae are membrane-associated proteins capable of inducing antibody production, and cytokine secretion. Therefore, these two proteins may be potential candidates for vaccine development against M. ovipneumoniae infection in sheep.

  18. Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses vasculogenic mimicry and proliferation of highly aggressive pancreatic cancer PaTu8988 cells

    International Nuclear Information System (INIS)

    Xu, Xing-dong; Yang, Lan; Zheng, Li-yun; Pan, Yan-yan; Cao, Zhi-fei; Zhang, Zhi-qing; Zhou, Quan-sheng; Yang, Bo; Cao, Cong

    2014-01-01

    Pancreatic cancer is one of the most aggressive human malignancies with a extremely low 5-year survival rate. Hence, the search for more effective anti-pancreatic cancer agents is urgent. PaTu8988 pancreatic cancer cells were treated with different concentrations of suberoylanilide hydroxamic acid (SAHA), cell survival, proliferation, migration and vasculogenic mimicry (VM) were analyzed. Associated signaling changes were also analyzed by RT-PCR and Western blots. Here, we reported that SAHA, a histone deacetylase inhibitor (HDACi), exerted significant inhibitory efficiency against pancreatic cancer cell survival, proliferation, migration and VM. SAHA dose-dependently inhibited PaTu8988 pancreatic cancer cell growth with the IC-50 of 3.4 ± 0. 7 μM. Meanwhile, SAHA suppressed PaTu8988 cell cycle progression through inducing G2/M arrest, which was associated with cyclin-dependent kinase 1 (CDK-1)/cyclin-B1 degradation and p21/p27 upregulation. Further, SAHA induced both apoptotic and non-apoptotic death of PaTu8988 cells. Significantly, SAHA suppressed PaTu8988 cell in vitro migration and cell-dominant tube formation or VM, which was accompanied by semaphorin-4D (Sema-4D) and integrin-β5 down-regulation. Our evidences showed that Akt activation might be important for Sema-4D expression in PaTu8988 cells, and SAHA-induced Sema-4D down-regulation might be associated with Akt inhibition. This study is among the first to report the VM formation in cultured human pancreatic cancer cells. And we provided strong evidence to suggest that SAHA executes significant anti-VM efficiency in the progressive pancreatic cancer cells. Thus, SAHA could be further investigated as a promising anti-pancreatic cancer agent

  19. COST Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar": ongoing research activities and third-year results

    Science.gov (United States)

    Pajewski, Lara; Benedetto, Andrea; Loizos, Andreas; Tosti, Fabio

    2016-04-01

    This work aims at disseminating the ongoing research activities and third-year results of the COST (European COoperation in Science and Technology) Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar." About 350 experts are participating to the Action, from 28 COST Countries (Austria, Belgium, Croatia, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Ireland, Italy, Latvia, Malta, Macedonia, The Netherlands, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Turkey, United Kingdom), and from Albania, Armenia, Australia, Colombia, Egypt, Hong Kong, Jordan, Israel, Philippines, Russia, Rwanda, Ukraine, and United States of America. In September 2014, TU1208 has been recognised among the running Actions as "COST Success Story" ("The Cities of Tomorrow: The Challenges of Horizon 2020," September 17-19, 2014, Torino, IT - A COST strategic workshop on the development and needs of the European cities). The principal goal of the COST Action TU1208 is to exchange and increase scientific-technical knowledge and experience of GPR techniques in civil engineering, whilst simultaneously promoting throughout Europe the effective use of this safe and non-destructive technique in the monitoring of infrastructures and structures. Moreover, the Action is oriented to the following specific objectives and expected deliverables: (i) coordinating European scientists to highlight problems, merits and limits of current GPR systems; (ii) developing innovative protocols and guidelines, which will be published in a handbook and constitute a basis for European standards, for an effective GPR application in civil- engineering tasks; safety, economic and financial criteria will be integrated within the protocols; (iii) integrating competences for the improvement and merging of electromagnetic scattering techniques and of data- processing techniques; this will lead to a novel freeware tool for the localization of

  20. Genetic dissection of the resistance to nine anthracnose races in the common bean differential cultivars MDRK and TU.

    Science.gov (United States)

    Campa, Ana; Giraldez, Ramón; Ferreira, Juan José

    2009-06-01

    Resistance to nine races of the pathogenic fungus Colletotrichum lindemuthianum, causal agent of anthracnose, was evaluated in F(3) families derived from the cross between the anthracnose differential bean cultivars TU (resistant to races, 3, 6, 7, 31, 38, 39, 102, and 449) and MDRK (resistant to races, 449, and 1545). Molecular marker analyses were carried out in the F(2) individuals in order to map and characterize the anthracnose resistance genes or gene clusters present in these two differential cultivars. The results of the combined segregation indicate that at least three independent loci conferring resistance to anthracnose are present in TU. One of them, corresponding to the previously described anthracnose resistance locus Co-5, is located in linkage group B7, and is formed by a cluster of different genes conferring specific resistance to races, 3, 6, 7, 31, 38, 39, 102, and 449. Evidence of intra-cluster recombination between these specific resistance genes was found. The second locus present in TU confers specific resistance to races 31 and 102, and the third locus confers specific resistance to race 102, the location of these two loci remains unknown. The resistance to race 1545 present in MDRK is due to two independent dominant genes. The results of the combined segregation of two F(4) families showing monogenic segregation for resistance to race 1545 indicates that one of these two genes is linked to marker OF10(530), located in linkage group B1, and corresponds to the previously described anthracnose resistance locus Co-1. The second gene conferring resistance to race 1545 in MDRK is linked to marker Pv-ctt001, located in linkage group B4, and corresponds to the Co-3/Co-9 cluster. The resistance to race 449 present in MDRK is conferred by a single gene, located in linkage group B4, probably included in the same Co-3/Co-9 cluster.

  1. COST Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar:" ongoing research activities and mid-term results

    Science.gov (United States)

    Pajewski, Lara; Benedetto, Andrea; Loizos, Andreas; Slob, Evert; Tosti, Fabio

    2015-04-01

    This work aims at presenting the ongoing activities and mid-term results of the COST (European COoperation in Science and Technology) Action TU1208 'Civil Engineering Applications of Ground Penetrating Radar.' Almost three hundreds experts are participating to the Action, from 28 COST Countries (Austria, Belgium, Croatia, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Ireland, Italy, Latvia, Malta, Macedonia, The Netherlands, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Turkey, United Kingdom), and from Albania, Armenia, Australia, Egypt, Hong Kong, Jordan, Israel, Philippines, Russia, Rwanda, Ukraine, and United States of America. In September 2014, TU1208 has been praised among the running Actions as 'COST Success Story' ('The Cities of Tomorrow: The Challenges of Horizon 2020,' September 17-19, 2014, Torino, IT - A COST strategic workshop on the development and needs of the European cities). The principal goal of the COST Action TU1208 is to exchange and increase scientific-technical knowledge and experience of GPR techniques in civil engineering, whilst simultaneously promoting throughout Europe the effective use of this safe and non-destructive technique in the monitoring of infrastructures and structures. Moreover, the Action is oriented to the following specific objectives and expected deliverables: (i) coordinating European scientists to highlight problems, merits and limits of current GPR systems; (ii) developing innovative protocols and guidelines, which will be published in a handbook and constitute a basis for European standards, for an effective GPR application in civil- engineering tasks; safety, economic and financial criteria will be integrated within the protocols; (iii) integrating competences for the improvement and merging of electromagnetic scattering techniques and of data- processing techniques; this will lead to a novel freeware tool for the localization of buried objects

  2. Rodents from the Upper Miocene Tuğlu Formation (Çankırı Basin, Central Anatolia, Turkey)

    OpenAIRE

    Joniak, Peter; de Bruijn, Hans

    2015-01-01

    The upper Miocene assemblages of rodents collected from two layers of the type section of the Tuğlu Formation (Çankırı Basin, Central Anatolia, Turkey) are described. The assemblage from the lower level is considerably less diverse than that from the upper level. It contains Progonomys together with Megacricetodon, which is a very unusual association. The assemblage from the upper layer shows a relatively high diversity with four species of Gliridae instead of only one in the lower layer. Apa...

  3. Combination of GPR with other NDT techniques in different fields of application - COST Action TU1208

    Science.gov (United States)

    Solla, Mercedes; Pérez-Gracia, Vega; Fontul, Simona; Santos-Assunçao, Sonia; Kucukdemirci, Melda

    2017-04-01

    common geophysical methods used for archaeological prospection (GPR and magnetometry). Regarding cultural heritage, an example in Barcelona (Spain) of the assessment of masonry structural elements, with embedded metallic targets, is included. Seismic tomography and 3D GPR imaging are applied, both supported with endoscopy. The results highlight the most affected areas of the structure and the existence of corroded metallic elements as consequence of humidity. Finally, two case studies support the importance of combining data in geological applications. Firstly, GPR and Electrical Resistivity Tomography (ERT) were combined for the analysis of the littoral drift and the tidal range affecting the transport of sediments in costal environments, and more particularly in O Adro Beach, in Vigo (Spain) that had been subjected to extension activities during the last decades. Secondly, the combination Multibeam Sonar and GPR data is presented for the study of a lake, which is an abandoned kaolin mine. Thus, it was possible to analyze the column of water in all the extension of the lake, while differentiating layers of lacustrine deposits and kaolin rock formations in subsurface. This work represents a contribution to the COST (European Cooperation in Science and Technology) Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar". The authors thank COST for funding the Action TU1208.

  4. Construction-man hour estimation for nuclear power plants

    International Nuclear Information System (INIS)

    Paek, J.H.

    1987-01-01

    This study centers on a statistical analysis of the preliminary construction time, main construction time, and total construction man hours of nuclear power plants. The use of these econometric techniques allows the major man hour driving variables to be identified through multivariate analysis of time-series data on over 80 United States nuclear power plants. The analysis made in this study provides a clearer picture of the dynamic changes that have occurred in the man hours of these plants when compared to engineering estimates of man hours, and produces a tool that can be used to project nuclear power plant man hours

  5. DNA barcoding for identification of 'Candidatus Phytoplasmas' using a fragment of the elongation factor Tu gene.

    Directory of Open Access Journals (Sweden)

    Olga Makarova

    Full Text Available Phytoplasmas are bacterial phytopathogens responsible for significant losses in agricultural production worldwide. Several molecular markers are available for identification of groups or strains of phytoplasmas. However, they often cannot be used for identification of phytoplasmas from different groups simultaneously or are too long for routine diagnostics. DNA barcoding recently emerged as a convenient tool for species identification. Here, the development of a universal DNA barcode based on the elongation factor Tu (tuf gene for phytoplasma identification is reported.We designed a new set of primers and amplified a 420-444 bp fragment of tuf from all 91 phytoplasmas strains tested (16S rRNA groups -I through -VII, -IX through -XII, -XV, and -XX. Comparison of NJ trees constructed from the tuf barcode and a 1.2 kbp fragment of the 16S ribosomal gene revealed that the tuf tree is highly congruent with the 16S rRNA tree and had higher inter- and intra- group sequence divergence. Mean K2P inter-/intra- group divergences of the tuf barcode did not overlap and had approximately one order of magnitude difference for most groups, suggesting the presence of a DNA barcoding gap. The use of the tuf barcode allowed separation of main ribosomal groups and most of their subgroups. Phytoplasma tuf barcodes were deposited in the NCBI GenBank and Q-bank databases.This study demonstrates that DNA barcoding principles can be applied for identification of phytoplasmas. Our findings suggest that the tuf barcode performs as well or better than a 1.2 kbp fragment of the 16S rRNA gene and thus provides an easy procedure for phytoplasma identification. The obtained sequences were used to create a publicly available reference database that can be used by plant health services and researchers for online phytoplasma identification.

  6. Bacillus anthracis Prolyl 4-Hydroxylase Interacts with and Modifies Elongation Factor Tu

    Energy Technology Data Exchange (ETDEWEB)

    Schnicker, Nicholas J. [Department; Razzaghi, Mortezaali [Department; Guha Thakurta, Sanjukta [Department; Chakravarthy, Srinivas [Biophysics; Dey, Mishtu [Department

    2017-10-17

    Prolyl hydroxylation is a very common post-translational modification and plays many roles in eukaryotes such as collagen stabilization, hypoxia sensing, and controlling protein transcription and translation. There is a growing body of evidence that suggests that prokaryotes contain prolyl 4-hydroxylases (P4Hs) homologous to the hypoxia-inducible factor (HIF) prolyl hydroxylase domain (PHD) enzymes that act on elongation factor Tu (EFTu) and are likely involved in the regulation of bacterial translation. Recent biochemical and structural studies with a PHD from Pseudomonas putida (PPHD) determined that it forms a complex with EFTu and hydroxylates a prolyl residue of EFTu. Moreover, while animal, plant, and viral P4Hs act on peptidyl proline, most prokaryotic P4Hs have been known to target free l-proline; the exceptions include PPHD and a P4H from Bacillus anthracis (BaP4H) that modifies collagen-like proline-rich peptides. Here we use biophysical and mass spectrometric methods to demonstrate that BaP4H recognizes full-length BaEFTu and a BaEFTu 9-mer peptide for site-specific proline hydroxylation. Using size-exclusion chromatography coupled small-angle X-ray scattering (SEC–SAXS) and binding studies, we determined that BaP4H forms a 1:1 heterodimeric complex with BaEFTu. The SEC–SAXS studies reveal dissociation of BaP4H dimeric subunits upon interaction with BaEFTu. While BaP4H is unusual within bacteria in that it is structurally and functionally similar to the animal PHDs and collagen P4Hs, respectively, this work provides further evidence of its promiscuous substrate recognition. It is possible that the enzyme might have evolved to hydroxylate a universally conserved protein in prokaryotes, similar to the PHDs, and implies a functional role in B. anthracis.

  7. Modular programming for tuberculosis control, the "AuTuMN" platform.

    Science.gov (United States)

    Trauer, James McCracken; Ragonnet, Romain; Doan, Tan Nhut; McBryde, Emma Sue

    2017-08-07

    Tuberculosis (TB) is now the world's leading infectious killer and major programmatic advances will be needed if we are to meet the ambitious new End TB Targets. Although mathematical models are powerful tools for TB control, such models must be flexible enough to capture the complexity and heterogeneity of the global TB epidemic. This includes simulating a disease that affects age groups and other risk groups differently, has varying levels of infectiousness depending upon the organ involved and varying outcomes from treatment depending on the drug resistance pattern of the infecting strain. We adopted sound basic principles of software engineering to develop a modular software platform for simulation of TB control interventions ("AuTuMN"). These included object-oriented programming, logical linkage between modules and consistency of code syntax and variable naming. The underlying transmission dynamic model incorporates optional stratification by age, risk group, strain and organ involvement, while our approach to simulating time-variant programmatic parameters better captures the historical progression of the epidemic. An economic model is overlaid upon this epidemiological model which facilitates comparison between new and existing technologies. A "Model runner" module allows for predictions of future disease burden trajectories under alternative scenario situations, as well as uncertainty, automatic calibration, cost-effectiveness and optimisation. The model has now been used to guide TB control strategies across a range of settings and countries, with our modular approach enabling repeated application of the tool without the need for extensive modification for each application. The modular construction of the platform minimises errors, enhances readability and collaboration between multiple programmers and enables rapid adaptation to answer questions in a broad range of contexts without the need for extensive re-programming. Such features are particularly

  8. Civil Engineering Applications of Ground Penetrating Radar: Research Perspectives in COST Action TU1208

    Science.gov (United States)

    Pajewski, Lara; Benedetto, Andrea; Loizos, Andreas; Slob, Evert; Tosti, Fabio

    2013-04-01

    can be used by GPR operators to identify the signatures generated by uncommon targets or by composite structures. Repeated evaluations of the electromagnetic field scattered by known targets can be performed by a forward solver, in order to estimate - through comparison with measured data - the physics and geometry of the region investigated by the GPR. It is possible to identify three main areas, in the GPR field, that have to be addressed in order to promote the use of this technology in the civil engineering. These are: a) increase of the system sensitivity to enable the usability in a wider range of conditions; b) research novel data processing algorithms/analysis tools for the interpretation of GPR results; c) contribute to the development of new standards and guidelines and to training of end users, that will also help to increase the awareness of operators. In this framework, the COST Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar", proposed by Lara Pajewski, "Roma Tre" University, Rome, Italy, has been approved in November 2012 and is going to start in April 2013. It is a 4-years ambitious project already involving 17 European Countries (AT, BE, CH, CZ, DE, EL, ES, FI, FR, HR, IT, NL, NO, PL, PT, TR, UK), as well as Australia and U.S.A. The project will be developed within the frame of a unique approach based on the integrated contribution of University researchers, software developers, geophysics experts, Non-Destructive Testing equipment designers and producers, end users from private companies and public agencies. The main objective of the COST Action TU1208 is to exchange and increase scientific-technical knowledge and experience of GPR techniques in civil engineering, whilst promoting the effective use of this safe and non-destructive technique in the monitoring of systems. In this interdisciplinary Action, advantages and limitations of GPR will be highlighted, leading to the identification of gaps in knowledge and technology

  9. Hvor må man gå?

    DEFF Research Database (Denmark)

    Baaner, Lasse

    2014-01-01

    færdsel på anden mands grund kan også have hjemmel i en servitut. Reglerne giver anledning til en masse stridigheder og er vanskelige at følge for de fleste af os. I Sverige og Norge har man allemandsret, men ikke i Danmark. Her skal man som mountainbiker, hundelufter, nøgenbader eller kajakroer følge...... nogle ret detaljerede regler, når man færdes på veje og afveje i Guds natur. For at vurdere, om man må færdes på et givent areal, skal man bruge en række informationer. Nogle af dem fi ndes ude i landskabet, mens andre fi ndes ved computeren. Kan man lave en adgangs-app, så man kan se, hvor man må...... færdes? Eller bare en app, som giver en mulighed for at vurderee, hvor man må færdes? Hvilke informationer kan man se on location og hvilke online? Kan der skabes online adgang til den nødvendige information, eller må man skilte sig ud af problemerne? Reglerne er jo – ligesom hastighedsbegrænsninger på...

  10. "A Is A": Spider-Man, Ayn Rand, and What Man Ought to Be

    OpenAIRE

    Brühwiler, Claudia Franziska

    2014-01-01

    In 1979, writer Tom DeFalco was paired with artist and cocreator of Spider-Man, Steve Ditko, to work on an issue of Machine Man, one of the many superheroes populating the universe of Marvel Comics. Instead of the usual introduction and business chatter, Ditko challenged DeFalco during a first conversation: "Are you Tom? What gives you the right to write about heroes?" (Tucker 2012). By the time of this exchange, Ditko had not only (co-) created and continued numerous superhero stories, rangi...

  11. The new V8 diesel engine from MAN; Der neue V8-Dieselmotor von MAN

    Energy Technology Data Exchange (ETDEWEB)

    Oehler, Georg; Vogel, Werner; Moeller, Inge; Tuerk, Jens [MAN Nutzfahrzeuge Motorenwerk Nuernberg AG, Nuernberg (Germany); Raup, Markus [MAN Nutzfahrzeuge, Steyr (Austria)

    2008-09-15

    MAN has developed a new V8 engine for the 16-l class with an output of 500 kW and 3,000 Nm of torque for its TGX and TGS ranges of heavy trucks. To reduce NO{sub x}, MAN has applied an SCR system with AdBlue injection. This article describes the engine concept, the design of the main components, the development of vehicle-specific add-on parts and the work carried out to optimise the combustion system and exhaust aftertreatment. (orig.)

  12. Design and Construction of Manned Lunar Base

    Science.gov (United States)

    Li, Zhijie

    2016-07-01

    Building manned lunar base is one of the core aims of human lunar exploration project, which is also an important way to carry out the exploitation and utilization of lunar in situ resources. The most important part of manned lunar base is the design and construction of living habitation and many factors should be considered including science objective and site selection. Through investigating and research, the scientific goals of manned lunar base should be status and characteristics ascertainment of lunar available in situ resources, then developing necessary scientific experiments and utilization of lunar in situ resources by using special environment conditions of lunar surface. The site selection strategy of manned lunar base should rely on scientific goals according to special lunar surface environment and engineering capacity constraints, meanwhile, consulting the landing sites of foreign unmanned and manned lunar exploration, and choosing different typical regions of lunar surface and analyzing the landform and physiognomy, reachability, thermal environment, sunlight condition, micro meteoroids protection and utilization of in situ resources, after these steps, a logical lunar living habitation site should be confirmed. This paper brings out and compares three kinds of configurations with fabricating processes of manned lunar base, including rigid module, flexible and construction module manned lunar base. 1.The rigid habitation module is usually made by metal materials. The design and fabrication may consult the experience of space station, hence with mature technique. Because this configuration cannot be folded or deployed, which not only afford limit working and living room for astronauts, but also needs repetitious cargo transit between earth and moon for lunar base extending. 2. The flexible module habitation can be folded in fairing while launching. When deploying on moon, the configuration can be inflatable or mechanically-deployed, which means under

  13. The Walk-Man Robot Software Architecture

    OpenAIRE

    Mirko Ferrati; Alessandro Settimi; Alessandro Settimi; Luca Muratore; Alberto Cardellino; Alessio Rocchi; Enrico Mingo Hoffman; Corrado Pavan; Dimitrios Kanoulas; Nikos G. Tsagarakis; Lorenzo Natale; Lucia Pallottino

    2016-01-01

    A software and control architecture for a humanoid robot is a complex and large project, which involves a team of developers/researchers to be coordinated and requires many hard design choices. If such project has to be done in a very limited time, i.e., less than 1 year, more constraints are added and concepts, such as modular design, code reusability, and API definition, need to be used as much as possible. In this work, we describe the software architecture developed for Walk-Man, a robot ...

  14. First exposure in man: toxicological considerations

    DEFF Research Database (Denmark)

    Spindler, Per; Sjöberg, P; Knudsen, Lisbeth E.

    2000-01-01

    The safety of a volunteer/patient who participate in the very first human trial relies on data from animal experimentation and on the design of the trial. Recommendations on the type and extent of preclinical safety studies that should be conducted prior to first dose in man have been developed...... for preclinical testing have had an important impact on the documented impressive safety record of phase I clinical trials. In this spirit we extend our warmest and sincerest thanks to Professor Jens S. Schou for his long and deep engagement in European and International harmonisation of preclinical test...

  15. Genetic effects of ionising radiation in man

    International Nuclear Information System (INIS)

    Sankaranarayanan, K.

    1991-01-01

    A review is given of genetic risk estimation in man. Topics covered include the methods used, the germ cell stages and radiation conditions relevant for genetic risk estimation, doubling dose estimates, the classification and prevalence of naturally-occurring genetic disorders, the source of data used in the direct method of risk estimation, the genetic risk estimates from the mid-1970s to the present, the estimates of genetic risk used in ICRP 26 in 1977 and ICRP's current assessment of genetic risks. (UK)

  16. Pantex Falling Man - Independent Review Panel Report.

    Energy Technology Data Exchange (ETDEWEB)

    Brannon, Nathan Gregory; L. Bertolini, N. Brannon, J. Olsen, B. Price, M. Steinzig, R. Wardle, & M. Winfield

    2014-11-01

    Consolidated Nuclear Security (CNS) Pantex took the initiative to organize a Review Panel of subject matter experts to independently assess the adequacy of the Pantex Tripping Man Analysis methodology. The purpose of this report is to capture the details of the assessment including the scope, approach, results, and detailed Appendices. Along with the assessment of the analysis methodology, the panel evaluated the adequacy with which the methodology was applied as well as congruence with Department of Energy (DOE) standards 3009 and 3016. The approach included the review of relevant documentation, interactive discussion with Pantex staff, and the iterative process of evaluating critical lines of inquiry.

  17. Nuclear propulsion tradeoffs for manned Mars missions

    International Nuclear Information System (INIS)

    Walton, L.A.; Malloy, J.D.

    1991-01-01

    A conjunction class split/sprint manned Mars exploration mission was studied to evaluate tradeoffs in performance characteristics of nuclear thermal rockets. A Particle Bed Reactor-based nuclear thermal rocket was found to offer a 38% to 52% total mass savings compared with a NERVA-based nuclear thermal rocket for this mission. This advantage is primarily due to the higher thrust-to-weight ratio of the Particle Bed Reactor nuclear rocket. The mission is enabled by nuclear thermal rockets. It cannot be performed practically using chemical propulsion

  18. Nuclear power, man, and the environment

    Energy Technology Data Exchange (ETDEWEB)

    Pentreath, R J

    1980-01-01

    Nuclear power is accepted as a reality in this description of the nature of radioactivity, its presence in the operation of a nuclear reactor, how and why some of the radioactivity is introduced into the environment in a controlled manner, and how these processes should be judged. The didactic approach makes the account an informative one rather than argumentative. The basic properties of radioactivity and its interaction with matter are described in the first chapter. Subsequent chapters deal with the radiation background, radiation and man, nuclear reactors and their fuel cycles, radioactive wastes and the public, environmental behavior and effects, and the acceptability of future discharges. 10 references, 41 figures, 57 tables. (DCK)

  19. Indirect evidence of calcitonin secretion in man.

    Science.gov (United States)

    Caniggia, A; Gennari, C; Vattimo, A; Nardi, P; Nuti, R

    1976-09-01

    1. The effect of calcitonin, a large amount of calcium given orally, pentagastrin and glucagon on plasma 47Ca radioactivity curves in subjects pretreated with 47Ca was examined. 2. A sudden increase of plasma radioactivity after intravenous administration of calcitonin and pentagastrin and after the oral calcium load was observed in normal subjects; the intravenous infusion of glucagon was less effective. 3. Two thyroparathyroidectomized patients who responded to the calcitonin infusion did not respond to the oral calcium load. 4. These data may be considered to offer indirect evidence of endogenous calcitonin secretion in man.

  20. Gastrointestinal absorption of uranium in man

    International Nuclear Information System (INIS)

    Larsen, R.P.; Orlandini, K.A.

    1984-01-01

    A method has been established for determining the fractional absorption of uranium directly in man. Measurements are made of the urinary excretion rates of uranium for individuals whose drinking water has a high 234 U to 238 U activity ratio and is the primary source of 234 U in their diets. For two individuals, the values obtained for the fractional absorption of 234 U were 0.004 and 0.006. The values obtained for the fractional absorption of 238 U, using a literature value for the 238 U intake from food, were 0.008 and 0.015. The present ICRP value is 0.20. 7 references, 1 table

  1. Monitoring man's impact in the coastal zone

    International Nuclear Information System (INIS)

    Benton, A.R. Jr.; Snell, W.W.

    1979-01-01

    The paper examines the monitoring of man's impact in the coastal zone. Color infrared photography shows destroyed or degraded wetlands or beaches, and makes possible relevant linear or aerial measurements with aerial photography. It can also categorize the environmental impacts which have accrued as the result of completion of water development projects. Aerial photography of the Texas coastal zone illustrates the nature and degree of damage likely to occur as a result of construction or maintenance projects. It is concluded that the method of assigning realistic values to unit areas of wetlands and beaches will make it feasible to incorporate the cost of estuarine damages into the cost estimates of water development schemes

  2. Man machine interface based on speech recognition

    International Nuclear Information System (INIS)

    Jorge, Carlos A.F.; Aghina, Mauricio A.C.; Mol, Antonio C.A.; Pereira, Claudio M.N.A.

    2007-01-01

    This work reports the development of a Man Machine Interface based on speech recognition. The system must recognize spoken commands, and execute the desired tasks, without manual interventions of operators. The range of applications goes from the execution of commands in an industrial plant's control room, to navigation and interaction in virtual environments. Results are reported for isolated word recognition, the isolated words corresponding to the spoken commands. For the pre-processing stage, relevant parameters are extracted from the speech signals, using the cepstral analysis technique, that are used for isolated word recognition, and corresponds to the inputs of an artificial neural network, that performs recognition tasks. (author)

  3. Man-caused seismicity of Kuzbass

    Science.gov (United States)

    Emanov, Alexandr; Emanov, Alexey; Leskova, Ekaterina; Fateyev, Alexandr

    2010-05-01

    A natural seismicity of Kuznetsk Basin is confined in the main to mountain frame of Kuznetsk hollow. In this paper materials of experimental work with local station networks within sediment basin are presented. Two types of seismicity display within Kuznetsk hollow have been understood: first, man-caused seismic processes, confined to mine working and concentrated on depths up to one and a half of km; secondly, seismic activations on depths of 2-56 km, not coordinated in plan with coal mines. Every of studied seismic activations consists of large quantity of earthquakes of small powers (Ms=1-3). From one to first tens of earthquakes were recorded in a day. The earthquakes near mine working shift in space along with mine working, and seismic process become stronger at the instant a coal-plough machine is operated, and slacken at the instant the preventive works are executed. The seismic processes near three lavas in Kuznetsk Basin have been studied in detail. Uplift is the most typical focal mechanism. Activated zone near mine working reach in diameter 1-1,5 km. Seismic activations not linked with mine working testify that the subsoil of Kuznetsk hollow remain in stress state in whole. The most probable causes of man-caused action on hollow are processes, coupled with change of physical state of rocks at loss of methane from large volume or change by mine working of rock watering in large volume. In this case condensed rocks, lost gas and water, can press out upwards, realizing the reverse fault mechanism of earthquakes. A combination of stress state of hollow with man-caused action at deep mining may account for incipient activations in Kuznetsk Basin. Today earthquakes happen mainly under mine workings, though damages of workings themselves do not happen, but intensive shaking on surface calls for intent study of so dangerous phenomena. In 2009 replicates of the experiment on research of seismic activations in area of before investigated lavas have been conducted

  4. Man - safety risk for nuclear power plants?

    International Nuclear Information System (INIS)

    Muehle, R.P.

    1991-01-01

    Analysis methods based on theories for action regulation provide essential information about the origin of operators' failures. Preventive measures based on this are adaptive training and pinpointed support by computer-aided information and calculation systems. Such systems do not meet their purpose by the fact that they employ high-performance equipment and there are some displays in the control room but only if they are substantially oriented towards man - subordinate to his thought and action structures. Some proposals are given with regard to those problems. (orig.) [de

  5. Adrenal Ewing's Sarcoma in an Elderly Man.

    Science.gov (United States)

    Toda, Kazuyoshi; Ishii, Sumiyasu; Yasuoka, Hidetoshi; Nishioka, Masaki; Kobayashi, Takayuki; Horiguchi, Kazuhiko; Tomaru, Takuya; Ozawa, Atsushi; Shibusawa, Nobuyuki; Satoh, Tetsurou; Koshi, Hiromi; Segawa, Atsuki; Shimizu, Shin-Ichi; Oyama, Tetsunari; Yamada, Masanobu

    2018-02-15

    Ewing's sarcoma usually arises in the bones of children and adolescents. We herein report a 74-year-old man with Ewing's sarcoma in the adrenal gland. The diagnosis was confirmed by a genetic test, pathological studies, and several imaging studies. He already had multiple liver metastases when he was transferred to our hospital and died on the 37th day. The diagnosis was further confirmed by autopsy studies. Adrenal Ewing's sarcoma is very rare, and our patient was older than other reported cases. Ewing's sarcoma should be considered even in elderly patients with adrenal tumors.

  6. Overview and comparative study of GPR international standards and guidelines - COST Action TU1208

    Science.gov (United States)

    Pajewski, Lara; Marciniak, Marian; Benedetto, Andrea; Tosti, Fabio

    2016-04-01

    Ground Penetrating Radar (GPR) can be effectively used for non-destructive testing of composite structures and diagnostics affecting the whole life-cycle of civil engineering works. Nevertheless, few recognised international standards exist in this field and inhomogeneous recommendations are present in different countries. Moreover, the levels of knowledge, awareness and experience regarding the use of GPR in civil engineering vary strongly across different European areas. The COST Action TU1208 is working hard on leveraging these differences, by sharing and disseminating knowledge and experience, as well as by developing guidelines and protocols for a safe and effective use of GPR in civil engineering. GPR users need to know which is the best way to conduct GPR measurements and what the quality level for the results should be. The TU1208 guidelines will ensure a higher efficiency and quality of GPR services and they will constitute a scientific basis for the introduction of European Standards on the application of GPR in civil engineering. The aim of this contribution is to present an in-depth overview and critical analysis of the existing GPR international and national standards and guidelines. The main documents considered in our work are listed and briefly described in the following. Three standards are provided by the American Society for Testing and Materials (ASTM), to guide the GPR use for subsurface investigation, evaluation of asphalt-covered concrete bridge decks, and determination of pavement-layer thickness: 1. ASTM D6432-11, Standard Guide for Using the Surface Ground Penetrating Radar Method for Subsurface Investigation, ASTM International, West Conshohocken, PA, 2011, www.astm.org, DOI: 10.1520/D6432-11. 2. ASTM D6087-08, Standard Test Method for Evaluating Asphalt-Covered Concrete Bridge Decks Using Ground Penetrating Radar, ASTM International, West Conshohocken, PA, 2008, www.astm.org, DOI: 10.1520/D6087-08. 3. ASTM D4748-10, Standard Test Method

  7. [A Listeria breast abscess in a man].

    Science.gov (United States)

    Marsaudon, E; Berthy, J; Mamoune, S; Deniel, A; Ksiyer, S; Tiuca, D

    2018-03-01

    Listeriosis is a food-borne illness leading to bacteriemia or central nervous system infection especially in pregnant women or high-risk patients. It is rarely a localized infection. Breast contamination has rarely been reported in lactating women. We report a breast abscess in man. A 80 year old man, hypertensive and arrhythmic, was explored for weakness and dehydration. Type 2 diabetes and chronic lymphocytic leukemia were diagnosed. Clinical examination disclosed a breast abcess related to L monocytogenes infection. Histopathological study also revealed a breast subcutaneous infiltration by chronic lymphocytic leukemia. Listeriosis sometimes uncover an unknown immunosuppression, especially in the elderly. Breast is a non-sterile tissue containing a stable microbiome partly from digestive origin. It can thereby be contaminated by Listeria. The specific cutaneous infiltrate of chronic lymphocytic leukemia can create the conditions for a local infection. Copyright © 2017 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier SAS. All rights reserved.

  8. Airborne radiation monitoring using a manned helicopter

    International Nuclear Information System (INIS)

    Sanada, Yukihisa; Nishizawa, Yukiyasu; Ishizaki, Azusa; Urabe, Yoshimi

    2017-01-01

    The Great East Japan Earthquake that occurred on 11 March 2011 generated a series of large tsunami waves that caused serious damage to the Fukushima Dai-ichi Nuclear Power Station, following which a large amount of radioactive material was discharged from the nuclear power plant into the environment. Airborne radiation measurements using a manned helicopter were applied to measure the radiation distribution immediately after accident as technique to quickly measure the radiation distribution over a wide area. In Japan, this technique was researched and developed in the 1980s. However, this technique and system were not applied immediately after the accident because standardization of analysis was not established and the Japanese system became deteriorated. This technique is important for post-accident studies at a nuclear facility. We summarized the methods of the airborne radiation measurement using a manned helicopter. In addition, measurement results of the dose rate distribution at the Fukushima Dai-ichi Nuclear Power Station are given in this paper. (author)

  9. Protection of man: the exposed individual

    Energy Technology Data Exchange (ETDEWEB)

    Bohnstedt, A.; Knebel, J.U. [Programme Nuclear Safety Research, Karlsruhe Institute of Technology, Herrmann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany); Breustedt, B. [Institute for Radiation Research, Karlsruhe Institute of Technology, Herrmann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany)

    2010-07-01

    Present methods for quantifying radiation exposure rely on a standardized reference man (75 kg) with defined average anatomical and physiological data. But individual person actually exposed differs from this idealized standard man. Therefore the focus of investigations at the Institute for Radiation Research (Institut fuer Strahlenforschung, ISF) which was founded at Karlsruhe Institute of Technology (Karlsruher Institut fuer Technologie, KIT) in 2009 is based on the vision to place the exposed individual with its anatomical and physiological particularities, under consideration of age, gender, body height, body shape and environment, in the centre of an individual-related quantification of the external and internal radiation exposure. Research work at the ISF is aiming at quantifying radiation exposure by improved determination of doses essentially caused by external radiation fields and the intake of radionuclides into the body. The three main topics of the institute are - external dosimetry (e.g. using a (voxel) model of the hand to simulate skin dose distribution); - internal dosimetry (e.g. body size related efficiency calibration of in-vivo counting equipment); - numerical methods/modeling (e.g. development of a mathematical/voxel-hybrid model of the human body). (authors)

  10. Climate and man in the Arctic

    International Nuclear Information System (INIS)

    1997-01-01

    The ever-changing climate shapes the Arctic landscape, influences life conditions for plants and animals and alters the availability of the living resources that play such and important part in the economy of Arctic peoples. It is essential that we try to understand the nature of climatic change and its effects on man and his environment. Only this way can we hope to be able to predict future changes that may have great consequences for the well-being of northern residents. In recent years many research projects have been addressing the subject and important advances have been made. At the same time it has become increasingly evident that the complexity of the whole issue calls for an integration of scientific approaches and for interdisciplinary collaboration. The seminar 'Climate and Man in the Arctic' provided an opportunity both to highlight important areas of climate related research and to discuss more general aspects of arctic research. Eight papers presented at the seminar are published in this volume. (au) 22 refs

  11. Adaptive myelination from fish to man.

    Science.gov (United States)

    Baraban, Marion; Mensch, Sigrid; Lyons, David A

    2016-06-15

    Myelinated axons with nodes of Ranvier are an evolutionary elaboration common to essentially all jawed vertebrates. Myelin made by Schwann cells in our peripheral nervous system and oligodendrocytes in our central nervous system has been long known to facilitate rapid energy efficient nerve impulse propagation. However, it is now also clear, particularly in the central nervous system, that myelin is not a simple static insulator but that it is dynamically regulated throughout development and life. New myelin sheaths can be made by newly differentiating oligodendrocytes, and mature myelin sheaths can be stimulated to grow again in the adult. Furthermore, numerous studies in models from fish to man indicate that neuronal activity can affect distinct stages of oligodendrocyte development and the process of myelination itself. This begs questions as to how these effects of activity are mediated at a cellular and molecular level and whether activity-driven adaptive myelination is a feature common to all myelinated axons, or indeed all oligodendrocytes, or is specific to cells or circuits with particular functions. Here we review the recent literature on this topic, elaborate on the key outstanding questions in the field, and look forward to future studies that incorporate investigations in systems from fish to man that will provide further insight into this fundamental aspect of nervous system plasticity. This article is part of a Special Issue entitled SI: Myelin Evolution. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

  12. Abstraction of man-made shapes

    KAUST Repository

    Mehra, Ravish; Zhou, Qingnan; Long, Jeremy; Sheffer, Alla; Gooch, Amy Ashurst; Mitra, Niloy J.

    2009-01-01

    Man-made objects are ubiquitous in the real world and in virtual environments. While such objects can be very detailed, capturing every small feature, they are often identified and characterized by a small set of defining curves. Compact, abstracted shape descriptions based on such curves are often visually more appealing than the original models, which can appear to be visually cluttered. We introduce a novel algorithm for abstracting three-dimensional geometric models using characteristic curves or contours as building blocks for the abstraction. Our method robustly handles models with poor connectivity, including the extreme cases of polygon soups, common in models of man-made objects taken from online repositories. In our algorithm, we use a two-step procedure that first approximates the input model using a manifold, closed envelope surface and then extracts from it a hierarchical abstraction curve network along with suitable normal information. The constructed curve networks form a compact, yet powerful, representation for the input shapes, retaining their key shape characteristics while discarding minor details and irregularities. © 2009 ACM.

  13. Online Mendelian Inheritance in Man (OMIM).

    Science.gov (United States)

    Hamosh, A; Scott, A F; Amberger, J; Valle, D; McKusick, V A

    2000-01-01

    Online Mendelian Inheritance In Man (OMIM) is a public database of bibliographic information about human genes and genetic disorders. Begun by Dr. Victor McKusick as the authoritative reference Mendelian Inheritance in Man, it is now distributed electronically by the National Center for Biotechnology Information (NCBI). Material in OMIM is derived from the biomedical literature and is written by Dr. McKusick and his colleagues at Johns Hopkins University and elsewhere. Each OMIM entry has a full text summary of a genetic phenotype and/or gene and has copious links to other genetic resources such as DNA and protein sequence, PubMed references, mutation databases, approved gene nomenclature, and more. In addition, NCBI's neighboring feature allows users to identify related articles from PubMed selected on the basis of key words in the OMIM entry. Through its many features, OMIM is increasingly becoming a major gateway for clinicians, students, and basic researchers to the ever-growing literature and resources of human genetics. Copyright 2000 Wiley-Liss, Inc.

  14. Improving containment mass and energy releases for CONTEMPT-LT/028 TU with RELAP5/MOD3

    International Nuclear Information System (INIS)

    DaSilva, H.C.; Choe, W.G.

    1996-01-01

    In order to obtain boundary conditions for RELAP5/MOD3 best estimate (BE) large break (LB) loss-of-coolant accident (LOCA) calculations, it is necessary to utilize a separate containment analysis code CONTEMPT-LT/028 TU, which in turn accepts mass and energy releases from the RELAP5/MOD3 calculation. When these boundary conditions are obtained, they are observed to be significantly lower than those reported in FSAR containment analyses. This motivates the present study, where RELAP5/MOD3 mass and energy releases are generated using the same assumptions listed in the FSAR containment calculations. Then CONTEMPT-LT/028 TU pressures and temperatures calculated with both sets of mass and energy releases are compared. It is seen that those obtained with the RELAP5/MOD3 input are still significantly lower, indicating a level of conservatism in the FSAR mass and energy releases that is even above that explicitly listed and also incorporated into the RELAP5/MOD3 calculation. An important conclusion from this finding is that Environmental Qualification (EQ) issues requiring containment re-analyses are likely to be easily resolved if new mass and energy releases are calculated with state-of-the-art LOCA codes modeling the entire reactor coolant system, even when conservative assumptions are incorporated

  15. COST Action TU1208 - Working Group 4 - Combined use of GPR and other NDT methods & GPR applications in geosciences

    Science.gov (United States)

    Pajewski, Lara; Solla, Mercedes; Fontul, Simona

    2017-04-01

    This work aims at presenting the main results achieved by Working Group (WG) 4 "Different applications of GPR and other NDT technologies in civil engineering" of the COST (European COoperation in Science and Technology) Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar" (www.GPRadar.eu, www.cost.eu). The main objective of the Action TU1208, started in April 2013 and ending in October 2017, is to exchange and increase scientific-technical knowledge and experience of Ground Penetrating Radar (GPR) techniques in civil engineering, whilst promoting in Europe the effective use of this safe non-destructive technique. The Action involves more than 150 Institutions from 28 COST Countries, a Cooperating State, 6 Near Neighbour Countries and 6 International Partner Countries. WG4 deals with the use of GPR outside from the civil engineering area, namely in archaeological prospecting and cultural heritage diagnostics, agriculture and management of water resources, investigation of polluted industrial sites, non-destructive testing of living tree trunks, planetary exploration, demining, localization of people buried under avalanches and debris, and more. Furthermore, this WG studies the integration of GPR with other Non-Destructive Testing (NDT) methods. The most relevant achievements stemming from WG4 will be presented during the 2017 EGU GA. These are: (i) The collection of thorough information on the state-of-the-art, ongoing studies, problems and future research needs on the topics of interest for this WG; (ii) The performance of a plethora of interesting case studies in important sites all over Europe, including well-known historical places such as Stonehenge (United Kingdom), Carnuntum (Austria), the Wawel Cathedral (Cracow, Poland), the Tholos Tomb of Acharnon (Athens, Greece), the Łazienki Royal Palace (Warsaw, Poland), and more; (iii) WG4 contributed to the TU1208 Education Pack, an open educational package conceived to teach GPR in University

  16. Formulations of the endophytic bacterium Bacillus subtilis Tu-100 suppress Sclerotinia sclerotiorum on oilseed rape and improve plant vigor in field trials conducted at separate locations

    Science.gov (United States)

    Sclerotinia sclerotiorum causes serious yield losses in crops in The People’s Republic of China. Two formulations of oilseed rape seed containing the endophytic bacterium Bacillus subtilis Tu-100 were evaluated for suppression of this pathogen in field trials conducted at two independent locations....

  17. :Examination of Sulfate production by CB05TU, RACM2 & RACM2 with SCI initiated SO2,oxidation in the Northern Hemisphere"

    Science.gov (United States)

    We employ the Community Multiscale Air Quality model to examine tropospheric sulfateproduction in the northern hemisphere using the Carbon Bond 2005 chemical mechanism withupdated toluene chemistry (CB05TU) and the Regional Atmospheric Chemistry Mechanism(RACM2) without and with ...

  18. Keeleuuendus ja tõlkimine Noor-Eesti kultuurilise utoopia raames : Villem Ridala tõlgitud "Süütu" näitel / Daniele Monticelli

    Index Scriptorium Estoniae

    Monticelli, Daniele

    2006-01-01

    Keeleuuenduse ja tõlketegevuse mõningastest olulistest seostest Noor-Eesti liikumisega alanud kultuurilise revolutsiooni kontekstis. Lähema lingvistilise vaatluse alla võetakse Gabriele D'Annunzio "L'Innocente" ("Süütu") Villem Ridala tõlkes. Järgneb: Keel ja Kirjandus, 2006, nr. 6, lk. 477-490

  19. Earthquake of Saint-Hilaire-de-Voust (Vendee) from February 12, 2018 (3h08 TU), Magnitude = 4,8 (Local Magnitude - CEA)

    International Nuclear Information System (INIS)

    Cushing, Edward; Provost, Ludmila

    2018-01-01

    A 3.9-4.0 magnitude superficial earthquake occurred at Saint-Hilaire-de-Voust (Vendee, France) on February 12, 2018 (3h08 TU). This brief note reviews, first, the historical and present day seismicity of the Armorican region, and then analyses the earthquake impact on the closest nuclear facilities (Pouzauges industrial irradiation facility, Chinon and Civaux NPPs)

  20. Investigation of functional aspects of the N-terminal region of elongation factor Tu from Escherichia coli using a protein engineering approach

    DEFF Research Database (Denmark)

    Laurberg, M; Mansilla, Francisco; Clark, Brian F. C.

    1998-01-01

    The function of the N-terminal region of elongation factor Tu is still unexplained. Until recently, it has not been visible in electron density maps from x-ray crystallography studies, but the presence of several well conserved basic residues suggest that this part of the molecule is of structural...

  1. Institute of place making : A project by the chair of Landscape Architecture at the TU Delft. Oerol 2013: Sense of place

    NARCIS (Netherlands)

    Pouderoijen, M.T.; Piccinini, D.

    2013-01-01

    This booklet shows the results of a project developed by TU Delft in a Master elective course offered by the chair of Landscape Architecture: Landscape Architecture ON site, being part of Oerol Festival 2013. The aim of the project was to express the landscape of Terschelling into a temporarily

  2. COST Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar": first-year activities and results

    Science.gov (United States)

    Pajewski, Lara; Benedetto, Andrea; Loizos, Andreas; Slob, Evert; Tosti, Fabio

    2014-05-01

    This work aims at presenting the first-year activities and results of COST (European COoperation in Science and Technology) Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar". This Action was launched in April 2013 and will last four years. The principal aim of COST Action TU1208 is to exchange and increase scientific-technical knowledge and experience of GPR techniques in civil engineering, whilst simultaneously promoting throughout Europe the effective use of this safe and non-destructive technique in the monitoring of infrastructures and structures. Moreover, the Action is oriented to the following specific objectives and expected deliverables: (i) coordinating European scientists to highlight problems, merits and limits of current GPR systems; (ii) developing innovative protocols and guidelines, which will be published in a handbook and constitute a basis for European standards, for an effective GPR application in civil- engineering tasks; safety, economic and financial criteria will be integrated within the protocols; (iii) integrating competences for the improvement and merging of electromagnetic scattering techniques and of data- processing techniques; this will lead to a novel freeware tool for the localization of buried objects, shape-reconstruction and estimation of geophysical parameters useful for civil engineering needs; (iv) networking for the design, realization and optimization of innovative GPR equipment; (v) comparing GPR with different NDT techniques, such as ultrasonic, radiographic, liquid-penetrant, magnetic-particle, acoustic-emission and eddy-current testing; (vi) comparing GPR technology and methodology used in civil engineering with those used in other fields; (vii) promotion of a more widespread, advanced and efficient use of GPR in civil engineering; and (viii) organization of a high-level modular training program for GPR European users. Four Working Groups (WGs) carry out the research activities. The first WG

  3. The Implementation of Madrasah-Based Management (MBM) at Man 1 and Man 2 Serang City, Banten, Indonesia--A Comparative Study

    Science.gov (United States)

    Muhajir

    2016-01-01

    This study aims to reveal how the real condition of management of Madrasah Aliyah Negeri (MAN) or Islamic Senior High School in Serang is, how the understanding of Madrasah-Based Management (MBM) for the people of MAN 2 and MAN 1 Serang is, and how the implementation of MBM in MAN 2 and MAN 1 Serang. This study has a substantial meaning, both…

  4. Nondestructive tests for railway monitoring. European Experience in COST Action TU1208

    Science.gov (United States)

    Fontul, Simona; Solla, Mercedes; Loizos, Andreas

    2016-04-01

    The railway monitoring is an important issue for a proper maintenance planning. With the increase in loads and travel speed, it is important to be able to diagnose the track defects and to plan the proper maintenance without interfering with the users. Traditionally, the maintenance actions are planned based on the geometric level parameters assessed without contact with the line, at traffic speed, by dedicated inspection vehicles. Nevertheless, the geometric condition of the line does not provide information on the defects causes. In order to complements the information on the causes, geophysics measurements can be performed in a nondestructive way. Among these later methods, Ground Penetrating Radar (GPR) is a quick and effective technique to evaluate infrastructure condition in a continuous manner, replacing or reducing the use of traditional drilling method. GPR application to railways infrastructures, during construction and monitoring phase, is relatively recent. It is based on the measuring of layers thicknesses and detection of structural changes. It also enables the assessment of materials properties that constitute the infrastructure and the evaluation of the different types of defects such as ballast pockets, fouled ballast, poor drainage, subgrade settlement and transitions problems. These deteriorations are generally the causes of vertical deviations in track geometry. Moreover, the development of new GPR systems with higher antenna frequencies, better data acquisition systems, more user friendly software and new algorithms for calculation of materials properties can lead to a regular use of GPR. A resume of the European experience in COST Action TU1208 of the application of GPR for railway monitoring and the measurement interpretation is presented in this paper. Also complementary nondestructive tests and other geophysical methods are referred, together with case studies of their application. The main troubleshooting and the needs for data analysis

  5. Inflammatory pain in experimental burns in man

    DEFF Research Database (Denmark)

    Pedersen, J L

    2000-01-01

    stimuli may be more reproducible. A methodological study also demonstrated that habituation to experimental pain developed as the study proceeded. Habituation is common in experimental pain models, and dividing analgesics and placebo evenly between the study days is one way of eliminating the effects......Human experimental pain models are important tools in pain research. The primary aims of pain research in normal man is 1) to provide insight in pain mechanisms, 2) to provide a rational basis for clinical trials of pain relieving interventions, and 3) to confirm the anti-nociceptive effects...... demonstrated in animal models. Most often clinical pain is due to tissue damage leading to acute inflammation and hyperalgesia, but only few human pain models have examined pain responses in injured tissues. Therefore, models with controlled and reversible tissue trauma are needed. The human burn model...

  6. Red man syndrome caused by vancomycin powder.

    Science.gov (United States)

    Nagahama, Yasunori; VanBeek, Marta J; Greenlee, Jeremy D W

    2018-04-01

    Red man syndrome (RMS) is a well-known hypersensitivity reaction caused by intravenous administration of vancomycin, with symptoms ranging from flushing, erythematous rash, pruritus, mild to profound hypotension, and even cardiac arrest. RMS has not previously been described from local application of vancomycin powder in a surgical wound, a technique increasingly utilized for infection prophylaxis in many surgical disciplines including neurosurgery. We describe the first reported case of RMS as a result of local intra-wound application of vancomycin powder for infection prophylaxis. A 73-year-old male with a history of Parkinson's disease underwent 2-stage deep brain stimulation implantation surgeries. Vancomycin powder was applied locally in the surgical wounds for infection prophylaxis during both of the surgeries. The patient developed a well-demarcated, geometric erythematous pruritic rash following the second surgery that was clinically diagnosed as RMS and resolved without sequelae. Copyright © 2018 Elsevier Ltd. All rights reserved.

  7. Evidence of Extrapancreatic Glucagon Secretion in Man

    DEFF Research Database (Denmark)

    Lund, Asger; Bagger, Jonatan I; Wewer Albrechtsen, Nicolai J

    2016-01-01

    . We applied novel analytical methods of plasma glucagon (sandwich enzyme-linked immunosorbent assay and mass-spectrometry-based proteomics) and show that 29-amino acid glucagon circulates in patients without a pancreas and that glucose stimulation of the gastrointestinal tract elicits significant......Glucagon is believed to be a pancreas-specific hormone and hyperglucagonemia has been shown to contribute significantly to the hyperglycemic state of patients with diabetes. This hyperglucagonemia has been thought to arise from alpha cell insensitivity to suppressive effects of glucose and insulin...... hyperglucagonemia in these patients. These findings emphasize the existence of extrapancreatic glucagon (perhaps originating from the gut) in man and suggest that it may play a role in diabetes secondary to total pancreatectomy....

  8. Quetelet, the average man and medical knowledge.

    Science.gov (United States)

    Caponi, Sandra

    2013-01-01

    Using two books by Adolphe Quetelet, I analyze his theory of the 'average man', which associates biological and social normality with the frequency with which certain characteristics appear in a population. The books are Sur l'homme et le développement de ses facultés and Du systeme social et des lois qui le régissent. Both reveal that Quetelet's ideas are permeated by explanatory strategies drawn from physics and astronomy, and also by discursive strategies drawn from theology and religion. The stability of the mean as opposed to the dispersion of individual characteristics and events provided the basis for the use of statistics in social sciences and medicine.

  9. [Quetelet, the average man and medical knowledge].

    Science.gov (United States)

    Caponi, Sandra

    2013-01-01

    Using two books by Adolphe Quetelet, I analyze his theory of the 'average man', which associates biological and social normality with the frequency with which certain characteristics appear in a population. The books are Sur l'homme et le développement de ses facultés and Du systeme social et des lois qui le régissent. Both reveal that Quetelet's ideas are permeated by explanatory strategies drawn from physics and astronomy, and also by discursive strategies drawn from theology and religion. The stability of the mean as opposed to the dispersion of individual characteristics and events provided the basis for the use of statistics in social sciences and medicine.

  10. Nuclear power, man and the environment

    International Nuclear Information System (INIS)

    Pentreath, R.J.

    1980-01-01

    This book is an attempt to describe briefly the nature of radioactivity, how it arises in the day-to-day operation of a nuclear reactor, how and why a small fraction is introduced into the environment in a controlled manner, and on what basis such judgements are made. It is an account of current practice, and an attempt to be didactic rather than polemic. As a general subject area it is one which involves many disciplines and therein lies its particular scientific interest, especially for the ecologist. It is also a subject area of continuing research and one of increasing public awareness. The chapters are entitled: radioisotopes - their characterization and interaction with matter; the radiation background; radiation and man; nuclear reactors and their fuel cycles; radioactive wastes and the public; environmental behaviour and effects; the future. (U.K.)

  11. The Preface. Reflections of a unpolitical man

    Directory of Open Access Journals (Sweden)

    Tomasz Mann

    2015-12-01

    Full Text Available “The Preface” was finished after the work on “Reflections of a unpolitical Man” and explains the reasons behind its creation. Thomas Mann decided that armed conflict between Germany and the West was the result of different perspectives. Democracy damages the world order and German values. The greatest advocate of democracy among Germans is the civilization’s man of letters. Mann undermines the value of his art and gives reasons for the disagreements with this revolutio-nary knowledge, which he calls “The new Pathos”. He develops the theory of the greatness of Germans as a nonpolitical nationality, recognizing Martin Luther as a reflection of this theory. He mentions the great minds of the 18th and 19th centuries to emphasize the most crucial differen- ces, seeing in himself a child of the 19th century. In conclusion, Mann claims that his opposition to democracy hastens its victory.

  12. A Diabetic Elderly Man with Finger Ulcer.

    Science.gov (United States)

    Mohamad, Noraini; Badrin, Salziyan; Wan Abdullah, Wan Noor Hasbee

    2018-03-01

    Fixed cutaneous sporotrichosis is a differential diagnosis that can be considered in diabetic patients who present with a poorly healing ulcer. Although its prevalence is low, it can occur in patients with immunocompromised status. Here we report a case of a 70-year-old man with diabetes mellitus who presented with a 1-month history of an unhealed ulcer over the tip of his left middle finger. He experienced a cat bite over his left middle finger 1 month prior to the appearance of the lesion. A skin biopsy revealed the presence of Sporothrix schenckii . Oral itraconazole 200 mg twice daily was started empirically and the patient showed marked improvement in the skin lesion after 2 months of therapy.

  13. Research with radioactive materials in man

    International Nuclear Information System (INIS)

    Roedler, H.D.

    1987-01-01

    In connection with the revision of the Radiation Protection Ordinance, for instance in section 41, the author - who can draw on his own experience as a referee for projects planned in the area of research with radioactive materials in man - deals with the following problems: 1. Quantifiable risk-benefit assessment as opposed to qualitative risk-benefit assessment based on medical experience. 2. Delimination of medicine and research by criteria such as application to healthy or sick persons, application of a new method or an already standardized one, application in the hope to achieve an individual benefit or without such hopes, and application with a view to obtaining results suitable to be generalized, in the course of which many borderline cases will crop up. 3. Legal requirements in section 41 of the Radiation Protection Ordinance with the demands for minimization of risks and quality assurance, and 4. application procedure and experience gathered so far. (TRV) [de

  14. The methodology of man-machine systems

    International Nuclear Information System (INIS)

    Hollnagel, E.

    1981-10-01

    This paper provides an elementary discussion of the problems of verification and validation in the context of the empirical evaluation of designs for man-machine systems. After a definition of the basic terms, a breakdown of the major parts of the process of evaluation is given, with the purpose of indicating where problems may occur. This is followed by a discussion of verification and validation, as two distinct concepts. Finally, some of the practical problems of ascertaining validity are discussed. The general conclusion is that rather than rely blindly on a well-established procedure or rule, one should pay attention to the meaningfulness of the aspects which are selected for observation, and the degree of systematism of the methods of observation and analysis. A qualitative approach is thus seen as complementary to a quantitative approach, rather than antithetical to it. (author)

  15. A young man with polyuria and lethargy.

    Science.gov (United States)

    Imtiaz, Salman; Qayyum, Shahid; Kafouri, Hala; Al Khoiter, Mohammad; Askar, Akram

    2011-07-01

    We report a 20-year-old man who presented to our emergency room with a history of polyuria, weakness, constipation, nausea, and vomiting of two months duration. History and clinical examination revealed a significant weight loss and mild hepatomegaly. Laboratory investigations revealed hypokalemia, hypernatremia, and severe metabolic acidosis and anemia. Ultra-sound of the abdomen revealed enlarged kidneys without hydronerphrosis. The patient developed paralysis due to further decline in serum potassium level, which improved after an aggressive fluid and electrolyte management. He was investigated extensively for polyuria and type of acidosis. The kidney biopsy showed interstitial leukemic infiltration. He was managed accordingly and recovered from the condition. This case demonstrates an unusual presentation of a hematological malignancy, which was a diagnostic as well as a management challenge.

  16. Calysto: Risk Management for Commercial Manned Spaceflight

    Science.gov (United States)

    Dillaman, Gary

    2012-01-01

    The Calysto: Risk Management for Commercial Manned Spaceflight study analyzes risk management in large enterprises and how to effectively communicate risks across organizations. The Calysto Risk Management tool developed by NASA's Kennedy Space Center's SharePoint team is used and referenced throughout the study. Calysto is a web-base tool built on Microsoft's SharePoint platform. The risk management process at NASA is examined and incorporated in the study. Using risk management standards from industry and specific organizations at the Kennedy Space Center, three methods of communicating and elevating risk are examined. Each method describes details of the effectiveness and plausibility of using the method in the Calysto Risk Management Tool. At the end of the study suggestions are made for future renditions of Calysto.

  17. Biomedical support of man in space

    Science.gov (United States)

    Pendergast, D. R.; Olszowka, A. J.; Rokitka, M. A.; Farhi, L. E.

    In its broadest sense, biomedical support of man in space must not be limited to assisting spacecraft crew during the mission; such support should also ensure that flight personnel be able to perform properly during landing and after leaving the craft. Man has developed mechanisms that allow him to cope with specific stresses in his normal habitat; there is indisputable evidence that, in some cases, the space environment, by relieving these stresses, has also allowed the adaptive mechanisms to lapse, causing serious problems after re-entry. Inflight biomedical support must therefore include means to simulate some of the normal stresses of the Earth environment. In the area of cardiovascular performance, we have come to rely heavily on complex feedback mechanisms to cope with two stresses, often combined: postural changes, which alter the body axis along which gravitational acceleration acts, and physical exercise, which increases the total load on the system. Unless the appropriate responses are reinforced continuously during flight, crew members may be incapacitated upon return. The first step in the support process must be a study of the way in which changes in g, even of short duration, affect these responses. In particular we should learn more about effects of g on the "on" and "off" dynamics, using a variety of approaches: increased acceleration on one hand at recumbency, immersion, lower body positive pressure, and other means of simulating some of the effects of low g, on the other. Once we understand this, we will have to determine the minimal exposure dose required to maintain the response mechanisms. Finally, we shall have to design stresses that simulate Earth environment and can be imposed in the space vehicle. Some of the information is already at hand; we know that several aspects of the response to exercise are affected by posture. Results from a current series of studies on the kinetics of tilt and on the dynamics of readjustment to exercise in

  18. Measurement of total body radioactivity in man

    International Nuclear Information System (INIS)

    Naversten, Y.

    1982-01-01

    Techniques for the determination of whole-body radioactivity in man using uncollimated NaI(Tl) detectors have been studied. Geometrical effects and photon attenuation effects due to the different shapes of humans as well as due to varying in-vivo radioactivity distributions have been evaluated particularly for scanning-bed geometries and the chair geometry. Theoretically it is shown that the attenuation effects are generally dominating, for full-energy-peak pulse-range methods. For the application in radiation protection a cheap and simple chair-geometry unit has been constructed and used at various places distantly from the home-laboratory, for studies of body activity of Cs-137 in northern Sweden. High body activities were found particularly in reindeer-breeding Lapps. The elimination rate of Cs-137 in man was studied in the stationary whole-body counter in Lund as well as with the field-system. For the study of the performances at low and high photon energies clinical applications of methods for gastro-intestinal absorption of vitamin B12 (Co-57; 122 keV) and total body potassium determination (K-40; 1.46 MeV, K-42; 1.52 MeV) have been evaluated. Theoretical and experimental results as well as experiences of applications in radiation protection and medicine show that the scanning-bed geometry effectively evens out redistributional effects. For optimum results, however, scatter-energy pulse-ranges rather than full-energy-peak ranges should be used. (Auth.)

  19. Two-Man Bobsled Push Start Analysis

    Directory of Open Access Journals (Sweden)

    Lopes Alexandre Dias

    2016-04-01

    Full Text Available The importance of push start times on bobsled performance was evidenced by some studies, but at this moment there is no article to the authors’ knowledge that describes the bobsled push start. Thus, the objectives of this study were to describe the two-man bobsled push start, analyze the differences between teams, and estimate the most important variable analyzed. We hypothesized that the pilot and brakeman athletes’ movement patterns during a bobsled pushing start can be described. The images used in this study were obtained during the men’s two-man XIV World Championship of Bobsled (2004. Fifteen best teams participating in the championship were recorded, and four start runs for each team were analyzed. The videos were captured by two digital video cameras. The pilot athletes were analyzed during the moment that they touched the lateral push bar of the sled, and the brakemen were analyzed during the first take-off and first landing. The teams were pooled in three groups of five teams using the final ranking of pushing time. We concluded that there was a distinct pattern movement for pilots and brakemen. The initial position of the majority of the pilots was localized slightly behind the bar. After touching the lateral bar, the pilots remained in a semi-squat position, pushing the sled forward in a pattern of marching movement. All brakemen used the board attached to the track as a support for both feet at the start. The brakeman gave the greatest contribution to break the inertia of the sled. There was no significant difference of movement between the three groups analyzed for the pilot and the brakeman.

  20. Analysis of transgenic wheat (Triticum aestivum L.) harboring a maize (Zea mays L.) gene for plastid EF-Tu: segregation pattern, expression and effects of the transgene.

    Science.gov (United States)

    Fu, Jianming; Ristic, Zoran

    2010-06-01

    We previously reported that transgenic wheat (Triticum aestivum L.) carrying a maize (Zea mays L.) gene (Zmeftu1) for chloroplast protein synthesis elongation factor, EF-Tu, displays reduced thermal aggregation of leaf proteins, reduced injury to photosynthetic membranes (thylakoids), and enhanced rate of CO(2) fixation following exposure to heat stress (18 h at 45 degrees C) [Fu et al. in Plant Mol Biol 68:277-288, 2008]. In the current study, we investigated the segregation pattern and expression of the transgene Zmeftu1 and determined the grain yield of transgenic plants after exposure to a brief heat stress (18 h at 45 degrees C). We also assessed thermal aggregation of soluble leaf proteins in transgenic plants, testing the hypothesis that increased levels of EF-Tu will lead to a non-specific protection of leaf proteins against thermal aggregation. The transgenic wheat displayed a single-gene pattern of segregation of Zmeftu1. Zmeftu1 was expressed, and the transgenic plants synthesized and accumulated three anti-EF-Tu cross-reacting polypeptides of similar molecular mass but different pI, suggesting the possibility of posttranslational modification of this protein. The transgenic plants also showed better grain yield after exposure to heat stress compared with their non-transgenic counterparts. Soluble leaf proteins of various molecular masses displayed lower thermal aggregation in transgenic than in non-transgenic wheat. The results suggest that overexpression of chloroplast EF-Tu can be beneficial to wheat tolerance to heat stress. Moreover, the results also support the hypothesis that EF-Tu contributes to heat tolerance by acting as a molecular chaperone and protecting heat-labile proteins from thermal aggregation in a non-specific manner.

  1. Moisture evaluation of wood material using GPR with WARR method - COST Action TU1208

    Science.gov (United States)

    Reci, Hamza; Sbart'i, Zoubir Mehdi; Pajewski, Lara; Marciniak, Marian

    2016-04-01

    This work deals with the study of the sensitivity of GPR electromagnetic waves to moisture variation in wood material in relation with the direction of fibers and polarization of Electromagnetic field. The relations between relative permittivity and moisture content and the amplitude attenuation with distance was a target study using the direct waves in Wide Angle Radar Reflection (WARR) configuration. Comparison of results measured with reflected waves and direct waves was of main importance since they have different behavior in relation with moisture variation, due to different path of propagation. This research activity has been carried out during one Short-Term Scientific Missions (STSM) funded by the COST (European Cooperation in Science and Technology) Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar" in November-December 2015. In context of durability evaluation of construction materials, several studies have been carried out by the I2M team, University of Bordeaux, using direct and reflected waves for the evaluation of water content on concrete and wood materials [1-3]. As related to the wood material there is one study carried out using the reflected waves on wood for different humidity and different wood samples, in all the direction of polarization using GPR technique ground coupled antenna at 1.5 GHz [3]. This work continued with different moisture content in order to study the behavior of direct waves as function of moisture. Results taken from those measurements are compared with them from Fixed Offset (reflected method) with one antenna (1.5GHz or 2.6GHz), realized from the previous studies from the I2M and already published [1-3]. The results taken from this work from the reflected waves, show that the effect of wood anisotropy is significant on the variation of relative permittivity with moisture content on wood sample and that is in good agreement with the previous results [3-6]. As related to the direct waves, a small

  2. Assessment of waterfront location in hardened concrete by GPR within COST Action TU1208

    Science.gov (United States)

    Rodríguez-Abad, Isabel; Klysz, Gilles; Balayssac, Jean Paul; Pajewski, Lara

    2016-04-01

    This work focuses on the analysis of the capability of Ground-Penetrating radar (GPR) technique for evaluating how the water penetrates into concrete samples by means of the assessment of the waterfront advance. Research activities have been carried out during a Short-Term Scientific Missions (STSMs) funded by the COST (European Cooperation in Science and Technology) Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar" in November 2015. The evaluation of water penetrability is crucial in most building materials, such us concrete, since, water and aggressive chemical agents dissolved therein contribute to the deterioration of the material. A number of techniques have been developed to measure their advance in concrete. Although the most common method for measuring water content is the gravimetric method by observing the change in mass, this method has a large number of disadvantages. In this context, non-destructive techniques as GPR play an interesting role. In particular, the application of GPR in the building materials area is providing very promising and interesting results regarding the building materials characterization and especially concrete deterioration evaluation [1-3]. In addition, recent experimental studies highlight the strong relation between wave propagation parameters (velocity and energy level) and water content advance [4-5]. Water content has a decisive influence on dielectric properties and those might be assessed by the study of the wave properties that are derived by using GPR. Therefore, the waterfront advance will result in a change on wave parameters. In line with this, this research is focused on the development of specific processing algorithms necessary to understand how the water penetrates and how the wave parameters will be affected regarding the location of the antenna in reference to the water absorption direction. For this purpose, concrete samples were manufactured, which after curing (90 days) and oven

  3. Innovative MAN Euro V engines without exhaust aftertreatment; Innovative MAN Euro V Motorisierung ohne Abgasnachbehandlung

    Energy Technology Data Exchange (ETDEWEB)

    Held, W.; Raab, G.; Schaller, K.V.; Gotre, W.; Lehmann, H.; Moeller, H.; Schroeppel, W. [MAN Nutzfahrzeuge AG, Muenchen (Germany); MAN Nutzfahrzeuge AG, Nuernberg (Germany); MAN Nutzfahrzeuge AG, Steyr (Austria)

    2009-07-01

    MAN Nutzfahrzeuge AG (Munich, Federal Republic of Germany) always is eager to offer products for the respective markets whereby the products are interesting for the customer under economic criteria. Additionally, the products shall not lack in the travelling comfort under consideration of the legal emission borders. Thus, a AdBlue {sup registered} free technology for all MAN series was already offered before the legal introduction of EURO IV. This technology is based on an internal-motor solution with external, cooled AGR and a PM-Cat {sup registered} -filter. This solution is esteemed highly by our customers because apart from the well-known advantages in relation to a SCR technology there were no losses with the operating cost. With EURO V which is inserted in some countries MAN Nutzfahrzeuge AG returns to a long-term experience with SCR technology. The motivation for the development of a AdBlue {sup registered} free solution was the positive feedback of our customers on the basis of MAN EURO IV AGR/PM Cat technology. With the developed EURO V AGR solution, other EURO IV solutions in line with market conditions for the 'Emerging markets' can be derived with which a technology without exhaust post-treatment can be offered worldwide for our customers. This technology presents the basis for a platform concept EURO IV/V and EURO VI. In this concept, EURO IV can be presented without subsequent treatment of exhaust gases, EURO V in connection with an Oxicat and EURO VI with a SCRT system. Here, the vehicle/engine concept presents the most important components for the individual series in particular. By means of these components, the goal EURO V was achieved internal-motor without losses of operating cost and life span in relation to SCR technologies.

  4. Operational Philosophy Concerning Manned Spacecraft Cabin Leaks

    Science.gov (United States)

    DeSimpelaere, Edward

    2011-01-01

    The last thirty years have seen the Space Shuttle as the prime United States spacecraft for manned spaceflight missions. Many lessons have been learned about spacecraft design and operation throughout these years. Over the next few decades, a large increase of manned spaceflight in the commercial sector is expected. This will result in the exposure of commercial crews and passengers to many of the same risks crews of the Space Shuttle have encountered. One of the more dire situations that can be encountered is the loss of pressure in the habitable volume of the spacecraft during on orbit operations. This is referred to as a cabin leak. This paper seeks to establish a general cabin leak response philosophy with the intent of educating future spacecraft designers and operators. After establishing a relative definition for a cabin leak, the paper covers general descriptions of detection equipment, detection methods, and general operational methods for management of a cabin leak. Subsequently, all these items are addressed from the perspective of the Space Shuttle Program, as this will be of the most value to future spacecraft due to similar operating profiles. Emphasis here is placed upon why and how these methods and philosophies have evolved to meet the Space Shuttle s needs. This includes the core ideas of: considerations of maintaining higher cabin pressures vs. lower cabin pressures, the pros and cons of a system designed to feed the leak with gas from pressurized tanks vs. using pressure suits to protect against lower cabin pressures, timeline and consumables constraints, re-entry considerations with leaks of unknown origin, and the impact the International Space Station (ISS) has had to the standard Space Shuttle cabin leak response philosophy. This last item in itself includes: procedural management differences, hardware considerations, additional capabilities due to the presence of the ISS and its resource, and ISS docking/undocking considerations with a

  5. Manned in Situ Confirmation of Lunar Ice

    Science.gov (United States)

    Gerené, S. P. B.; Hummeling, R. W. J.; Ockels, W. J.

    A study is performed to investigate the feasibility of a manned expedition to the Moon using the European Ariane-5 launcher. The primary objective of this lunar mission is to confirm the presence of water at the South-Pole craters. It is believed that these permanently shadowed craters contain water in the form of ice. Secondary objective is to perform lunar surface science and making a first step towards a lunar outpost. Early results show that a minimum of two Ariane-5 launches is required. In this `two Ariane' scenario the first launch will bring a Lunar Landing Vehicle (LLV) into low lunar orbit. The second will launch two astronauts in a Crew Transfer Vehicle into a rendez- vous trajectory with the LLV. Arrived at the Moon, the astronauts will enter the LLV, undock from the CTV and land at the designated site located near the rim of the South-Pole Shackleton crater. The transfer strategy for both spacecraft will be the so-called direct transfer, taking about four days. At arrival the LLV will start mapping the landing site at a ground resolution of one meter. As a consequence of the polar orbit, the CTV has to arrive fourteen days later and surface operations can take about twelve days, accumulating in a total mission-duration of 36 days. 32 days for the CTV and 22 days for the LLV. In case a `two Ariane' flight does not posses sufficient capabilities also a `three Ariane' scenario is developed, in which the LLV is split-up into two stages and launched separately. These two will dock at the Moon forming a descent stage and an ascent stage. The third launch will be a CTV. During surface operations, astronauts will set up a solar power unit, install the sample retrieval system and carry out surface science. Samples of the crater floor will be retrieved by means of a probe or robot guided along a cable suspended over the crater rim. Also, this paper shows the way in which European astronauts can be brought to the Moon for other future missions, like the

  6. A Whitham-Theory Sonic-Boom Analysis of the TU-144 Aircraft at a Mach Number of 2.2

    Science.gov (United States)

    Mack, Robert J.

    1999-01-01

    Officially, the Tu-144 was the first supersonic-cruise, passenger-carrying aircraft to enter commercial service. Design, construction, and testing were carried out by the Soviet Union, flight certification was by the Soviet Union, and the only regular passenger flights were scheduled and flown across the territory of the Soviet Union. Although it was not introduced to international passenger service, there were many significant engineering accomplishments achieved in the design, production, and flight of this aircraft. Development of the aircraft began with a prototype stage. Systematic testing and redesign led to a production aircraft in discrete stages that measurably improved the performance of the aircraft from the starting concept to final aircraft certification. It flew in competition with the English-French Concorde for a short time, but was withdrawn from national commercial service due to a lack of interest by airlines outside the Soviet Union. NASA became interested in the Tu- 144 aircraft when it was offered for use as a flying "testbed" in the study of operating characteristics of a supersonic-cruise commercial airplane. Since it had been in supersonic-cruise service, the Tu- 144 had operational characteris'tics similar to those anticipated in the conceptual aircraft designs being studied by the United States aircraft companies. In addition to the other operational tests being conducted on the Tu-144 aircraft, it was proposed that two sets of sonic-boom pressure signature measurements be made. The first set would be made on the ground, using techniques and devices similar to those in reference I and many other subsequent studies. A second set would be made in the air with an instrumented aircraft flying close under the Tu-144 in supersonic flight. Such in-flight measurements would require pressure gages that were capable of accurately recording the flow-field overpressures generated by the Tu- 144 at relatively close distances under the vehicle

  7. COST Action TU1208 - Working Group 2 - GPR surveying of pavements, bridges, tunnels and buildings; underground utility and void sensing

    Science.gov (United States)

    Pajewski, Lara; Benedetto, Andrea; Derobert, Xavier; Fontul, Simona; Govedarica, Miro; Gregoire, Colette; Loizos, Andreas; Perez-Gracia, Vega; Plati, Christina; Ristic, Aleksandar; Tosti, Fabio; Van Geem, Carl

    2017-04-01

    This work aims at presenting the main results achieved by Working Group (WG) 2 "GPR surveying of pavements, bridges, tunnels and buildings; underground utility and void sensing" of the COST (European COoperation in Science and Technology) Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar" (www.GPRadar.eu, www.cost.eu). The principal goal of the Action, started in April 2013 and ending in October 2017, is to exchange and increase scientific-technical knowledge and experience of Ground Penetrating Radar (GPR) techniques in civil engineering, whilst promoting throughout Europe the effective use of this safe non-destructive technique. The Action involves more than 300 Members from 28 COST Countries, a Cooperating State, 6 Near Neighbour Countries and 6 International Partner Countries. The most interesting achievements of WG2 include: 1. The state of the art on the use of GPR in civil engineering was composed and open issues were identified. The few existing international/national guidelines/protocols for GPR inspection in civil engineering were reviewed and discussed. Academic end-users, private companies and stakeholders presented their point of view and needs. 2. Guidelines for investigating flexible pavement by using GPR were prepared, with particular regard to layer-thickness assessment, moisture-content sensing, pavement-damage detection and classification, and other main GPR-based investigations in pavement engineering. 3. Guidelines for GPR sensing and mapping of underground utilities and voids were prepared, with a main focus on urban areas. 4. Guidelines for GPR assessment of concrete structures, with particular regard to inspections in bridges and tunnels, were prepared. 5. A report was composed, including a series of practical suggestions and very useful information to guide GPR users during building inspection. 6. WG2 Members carried out a plethora of case studies where GPR was used to survey roads, highways, airport runways, car

  8. Is the sup(99m)Tc-Thyroid-uptake (TcTU) a valid measure of thyroidal trapping

    International Nuclear Information System (INIS)

    Mahlstedt, J.; Hotze, L.A.; Schwedes, H.G.; Joseph, K.

    1979-01-01

    In 2067 euthyroid goitrous patients living in an iodine deficient area which is under medical service of the university of Marburg/L. (W. Germany) sup(99m)Tc-Thyroid-Uptake as a measure for thyroidal trapping has been evaluated with respect to age and sex dependance. For both sexes there is marked decrease with increasing age, the values in the female sex are always higher than in the male sex. Comparison with the relevant results of ODDIE and coworkers reveals general correspondence, the differences of a more strong age and sex dependance are to expect in a region of iodine deficiency. Thus, the study confirms the validity of TcTU as a measure of thyroidal trapping. (orig.) [de

  9. 46 CFR 131.920 - Level of manning.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Level of manning. 131.920 Section 131.920 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Miscellaneous § 131.920 Level of manning. Each vessel must carry the personnel required by the Certificate of...

  10. 77 FR 21555 - Manning, Richard W.; Notice of Filing

    Science.gov (United States)

    2012-04-10

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ID-6835-001] Manning, Richard W.; Notice of Filing Take notice that on April 2, 2012, Richard W. Manning submitted for filing... not serve to make protestants parties to the proceeding. Any person wishing to become a party must...

  11. Who is afraid of a black Spider(-Man)?

    OpenAIRE

    Ora C. McWilliams

    2013-01-01

    An Internet post asking about Spider-Man's race in a film turned into an Internet campaign about an actor that led fans to interact with each other as well as with the actor, which in turn led to the attention of media producers, which resulted in a change in Spider-Man's race in a print comic book.

  12. Who is afraid of a black Spider(-Man?

    Directory of Open Access Journals (Sweden)

    Ora C. McWilliams

    2013-06-01

    Full Text Available An Internet post asking about Spider-Man's race in a film turned into an Internet campaign about an actor that led fans to interact with each other as well as with the actor, which in turn led to the attention of media producers, which resulted in a change in Spider-Man's race in a print comic book.

  13. Life Cycle Assessment of man-made cellulose fibres

    NARCIS (Netherlands)

    Shen, L.; Patel, M.K.

    2010-01-01

    The production of textile materials has undergone dramatic changes in the last century. Man-made cellulose fibres have played an important role for more than 70 years. Today, the man-made cellulose fibre industry is the worldwide second largest biorefinery (next to the paper industry). In the last

  14. Environmental behaviour of radionuclides and transfer to man

    International Nuclear Information System (INIS)

    Smith, H.

    1982-01-01

    The environmental behaviour of the radionuclides making the major contribution to man's irradiation through diet is described. The following stages are emphasized: transfer of radionuclides to plants; transfer of radionuclides to animals; metabolism of inhaled or ingested radionuclides in animals providing food for man; transfer of radionuclides through the aquatic environment; application of food chain models. (43 references)

  15. Environmental impact assessment of man-made cellulose fibres

    NARCIS (Netherlands)

    Shen, L.; Worrell, E.; Patel, M.K.

    2010-01-01

    Man-made cellulose fibres have played an important role in the production of textile products for more than 70 years. The purpose of this study is to assess the environmental impact of man-made cellulose fibres. Life cycle assessment (LCA) was conducted for three types of fibres (i.e. Viscose, Modal

  16. The Creation of Man and Woman in Early Jewish Literature

    NARCIS (Netherlands)

    Ruiten, J.T.A.G.M. van; Luttikhuizen, G P

    2000-01-01

    J.T.A.G.M. van Ruiten, “The Creation of Man and Woman in Early Jewish Literature,” in The Creation of Man and Woman: Interpretations of the Biblical Narratives in Jewish and Christian Traditions (ed. Gerard P. Luttikhuizen; Themes in Biblical Narrative 3; Leiden, Boston, and Köln: Brill, 2000),

  17. 46 CFR 131.420 - Manning and supervision.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Manning and supervision. 131.420 Section 131.420 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Sufficiency and Supervision of Crew of Survival Craft § 131.420 Manning and supervision. (a) There must be enough trained persons aboard each survival craf...

  18. 42 CFR 84.101 - Man test 5; requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Man test 5; requirements. 84.101 Section 84.101 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.101 Man test 5; requirements....

  19. Man and SuperNature. Lecture 12, September 27, 1946

    Science.gov (United States)

    Montessori, Maria

    2015-01-01

    "Man and SuperNature" is a lyrical chapter in the 1946 London course following the emergence of Cosmic Education in Kodaikanal, India. Montessori contrasts the adaptation required of animals for their survival to conscious human adaptation. Animals exist and adapt to nature, but man can alter nature and change the environment.…

  20. 42 CFR 84.102 - Man test 6; requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Man test 6; requirements. 84.102 Section 84.102 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.102 Man test 6; requirements....

  1. 42 CFR 84.103 - Man tests; performance requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Man tests; performance requirements. 84.103 Section 84.103 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.103 Man tests;...

  2. Sexual Harassment and Manly Sports: Are They Related?

    Science.gov (United States)

    Murolo, Nancy Maurer; Schmelkin, Liora Pedhazur

    This study investigates the relationship between sexual harassment and participation in "manly" sports (i.e., football, baseball, basketball, soccer, and wrestling) at the high school level. Manly sports are defined as those sports that celebrate values of dominance, aggression, male solidarity, and female exclusion. Participants were 353 11th-…

  3. The Walk-Man Robot Software Architecture

    Directory of Open Access Journals (Sweden)

    Mirko Ferrati

    2016-05-01

    Full Text Available A software and control architecture for a humanoid robot is a complex and large project, which involves a team of developers/researchers to be coordinated and requires many hard design choices. If such project has to be done in a very limited time, i.e., less than 1 year, more constraints are added and concepts, such as modular design, code reusability, and API definition, need to be used as much as possible. In this work, we describe the software architecture developed for Walk-Man, a robot participant at the Darpa Robotics Challenge. The challenge required the robot to execute many different tasks, such as walking, driving a car, and manipulating objects. These tasks need to be solved by robotics specialists in their corresponding research field, such as humanoid walking, motion planning, or object manipulation. The proposed architecture was developed in 10 months, provided boilerplate code for most of the functionalities required to control a humanoid robot and allowed robotics researchers to produce their control modules for DRC tasks in a short time. Additional capabilities of the architecture include firmware and hardware management, mixing of different middlewares, unreliable network management, and operator control station GUI. All the source code related to the architecture and some control modules have been released as open source projects.

  4. Environmental pathways of radioactivity to man

    International Nuclear Information System (INIS)

    Johns, T.F.

    1979-12-01

    The report reviews and discusses the environmental pathways by which radioactive materials can lead to the irradiation of man, in a way that should be understood by non-specialists who have neither the time nor the knowledge to study all of the relevant literature on this subject. The role of these environmental pathways in the general structure of radiological protection is considered, and the various mechanisms which lead to the dispersion or re-concentration of radioactive materials are discussed at some length. Particular groups of radionuclides from the nuclear power industry are considered in some detail. Similarly the question of the corresponding pathways from naturally-occurring radioactive materials is covered. The doses to animals and plants resulting from the nuclear industry are examined, and it is concluded that there is no reason to expect that these doses will lead to significant harm. Finally a summary is presented, and it is noted that it has been possible to obtain a very extensive knowledge of the behaviour of radionuclides in the environment only because of the extreme sensitivity of the techniques available for their detection, identification and assay. As a result a fund of knowledge has been built up about the behaviour of radioactive materials in the environment which is far more extensive than our knowledge of the behaviour of many highly toxic chemicals which are also discharged into the environment. (UK)

  5. Radiation-induced cancers in man

    International Nuclear Information System (INIS)

    Hirose, Fumio

    1978-01-01

    Radiation-induced cancers in man were divided into three groups, a group in which cancers occurred after atomic bomb exposure, a group in which cancers occurred in radiologists and other medical specialists, and a group in which cancers occurred after exposure to diagnostic radiation, and they were summarized. In atomic bomb survivors leukemia, thyroid cancer, salivary gland cancer, lung cancer, and breast cancer occurred so frequently. In addition to them, mortality ratios by malignant lymphoma, stomach cancer, esophageal cancer, and by cancer of urinary tract were increased. The incidence of leukemia was decreased in those who treated radiation owing to the development of the protection of occupational exposure, and the incidence of radiation-induced cancers was decreased in patients owing to the improvement of therapy. However, a new problem has arisen as to the occurrence of cancers after medical exposure, such as various histological types of cancers after the treatment of skin diseases on the head, and breast cancer after the treatment of pneumothorax. Dose-to-effect relation, hereditary factors, effect of age, immunological influences and endocrine actions were also studied in each radiation-induced cancer. (Ichikawa, K.)

  6. Metabolic studies in man using stable isotopes

    International Nuclear Information System (INIS)

    Faust, H.; Jung, K.; Krumbiegel, P.

    1993-01-01

    In this project, stable isotope compounds and stable isotope pharmaceuticals were used (with emphasis on the application of 15 N) to study several aspects of nitrogen metabolism in man. Of the many methods available, the 15 N stable isotope tracer technique holds a special position because the methodology for application and nitrogen isotope analysis is proven and reliable. Valid routine methods using 15 N analysis by emission spectrometry have been demonstrated. Several methods for the preparation of biological material were developed during our participation in the Coordinated Research Programme. In these studies, direct procedures (i.e. use of diluted urine as a samples without chemical preparation) or rapid isolation methods were favoured. Within the scope of the Analytical Quality Control Service (AQCS) enriched stable isotope reference materials for medical and biological studies were prepared and are now available through the International Atomic Energy Agency. The materials are of special importance as the increasing application of stable isotopes as tracers in medical, biological and agricultural studies has focused interest on reliable measurements of biological material of different origin. 24 refs

  7. Design options for advanced manned launch systems

    Science.gov (United States)

    Freeman, Delma C.; Talay, Theodore A.; Stanley, Douglas O.; Lepsch, Roger A.; Wilhite, Alan W.

    1995-03-01

    Various concepts for advanced manned launch systems are examined for delivery missions to space station and polar orbit. Included are single-and two-stage winged systems with rocket and/or air-breathing propulsion systems. For near-term technologies, two-stage reusable rocket systems are favored over single-stage rocket or two-stage air-breathing/rocket systems. Advanced technologies enable viable single-stage-to-orbit (SSTO) concepts. Although two-stage rocket systems continue to be lighter in dry weight than SSTO vehicles, advantages in simpler operations may make SSTO vehicles more cost-effective over the life cycle. Generally, rocket systems maintain a dry-weight advantage over air-breathing systems at the advanced technology levels, but to a lesser degree than when near-term technologies are used. More detailed understanding of vehicle systems and associated ground and flight operations requirements and procedures is essential in determining quantitative discrimination between these latter concepts.

  8. When does "economic man" dominate social behavior?

    Science.gov (United States)

    Camerer, Colin F; Fehr, Ernst

    2006-01-06

    The canonical model in economics considers people to be rational and self-regarding. However, much evidence challenges this view, raising the question of when "Economic Man" dominates the outcome of social interactions, and when bounded rationality or other-regarding preferences dominate. Here we show that strategic incentives are the key to answering this question. A minority of self-regarding individuals can trigger a "noncooperative" aggregate outcome if their behavior generates incentives for the majority of other-regarding individuals to mimic the minority's behavior. Likewise, a minority of other-regarding individuals can generate a "cooperative" aggregate outcome if their behavior generates incentives for a majority of self-regarding people to behave cooperatively. Similarly, in strategic games, aggregate outcomes can be either far from or close to Nash equilibrium if players with high degrees of strategic thinking mimic or erase the effects of others who do very little strategic thinking. Recently developed theories of other-regarding preferences and bounded rationality explain these findings and provide better predictions of actual aggregate behavior than does traditional economic theory.

  9. Bladder necrosis: 'A man without a bladder'.

    Science.gov (United States)

    Bosschieter, Judith; Oudshoorn, Frederik H K; Meuleman, Eric J H; Nieuwenhuijzen, Jakko A

    2018-02-17

    Since the use of antibiotics, bladder necrosis has become a rare condition. We report a case of bladder necrosis in a 90-year-old man following urinary retention. After insertion of a transurethral catheter (TUC), 2 L of urine was evacuated. In the following days, the TUC became intermittently blocked. Adequate bladder drainage could not be obtained despite intensive rinsing and placement of a suprapubic catheter. On surgical exploration necrosis of almost the entire bladder wall, except for the trigone, was encountered. Surgical debridement of the non-viable bladder wall without opening the abdominal cavity was conducted, and a TUC was placed in the Retzius cavity to ensure evacuation of urine. Since the patient was haemodynamically unstable, construction of a urinary diversion was waived and urinary drainage of the Retzius cavity by the TUC was accepted, resulting in adequate urinary drainage without compromising renal function. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  10. NASA Laboratory Analysis for Manned Exploration Missions

    Science.gov (United States)

    Krihak, Michael K.; Shaw, Tianna E.

    2014-01-01

    The Exploration Laboratory Analysis (ELA) project supports the Exploration Medical Capability Element under the NASA Human Research Program. ELA instrumentation is identified as an essential capability for future exploration missions to diagnose and treat evidence-based medical conditions. However, mission architecture limits the medical equipment, consumables, and procedures that will be available to treat medical conditions during human exploration missions. Allocated resources such as mass, power, volume, and crew time must be used efficiently to optimize the delivery of in-flight medical care. Although commercial instruments can provide the blood and urine based measurements required for exploration missions, these commercial-off-the-shelf devices are prohibitive for deployment in the space environment. The objective of the ELA project is to close the technology gap of current minimally invasive laboratory capabilities and analytical measurements in a manner that the mission architecture constraints impose on exploration missions. Besides micro gravity and radiation tolerances, other principal issues that generally fail to meet NASA requirements include excessive mass, volume, power and consumables, and nominal reagent shelf-life. Though manned exploration missions will not occur for nearly a decade, NASA has already taken strides towards meeting the development of ELA medical diagnostics by developing mission requirements and concepts of operations that are coupled with strategic investments and partnerships towards meeting these challenges. This paper focuses on the remote environment, its challenges, biomedical diagnostics requirements and candidate technologies that may lead to successful blood-urine chemistry and biomolecular measurements in future space exploration missions.

  11. Environmental pathways of radioactivity to man

    International Nuclear Information System (INIS)

    Johns, T.F.

    1983-01-01

    An attempt has been made to discuss environmental pathways and their significance in a way which will be understood by non-specialists. The role of these pathways in the general structure of radiological protection is explained and the more important pathways to man from releases into the air and the aquatic environment are discussed generally. The various mechanisms which lead to the dispersion or reconstruction of radioactive materials are discussed and their importance stressed. The more important pathways for particular groups of radionuclides from the nuclear power industry are dealt with in detail and information resulting from many theoretical and practical studies of the situations at particular locations summarized. There is detailed discussion about the doses to local population groups and about worldwide doses as a result of the release of certain long-lived radioactive species. The corresponding pathways and resulting doses from natural radiation are detailed to illustrate that the doses from the nuclear power industry are small in comparison, and brief consideration is given to animal and plant doses from the industry. (U.K.)

  12. Man-machine interface versus full automation

    International Nuclear Information System (INIS)

    Hatton, V.

    1984-01-01

    As accelerators grow in size and complexity of operation there is an increasing economical as well as an operational incentive for the controls and operations teams to use computers to help the man-machine interface. At first the computer network replaced the traditional controls racks filled with knobs, buttons and digital displays of voltages and potentiometer readings. The computer system provided the operator with the extension of his hands and eyes. It was quickly found that much more could be achieved. Where previously it was necessary for the human operator to decide the order of the actions to be executed by the computer as a result of a visual indication of malfunctioning of the accelerator, now the operation is becoming more and more under the direct control of the computer system. Expert knowledge is programmed into the system to help the non-specialist make decision and to safeguard the equipment. Machine physics concepts have been incorporated and critical machine parameters can be optimised easily by the physicists or operators without any detailed knowledge of the intervening medium or of the equipment being controlled. As confidence grows and reliability improves, more and more automation can be added. How far can this process of automation replace the skilled operator. Can the accelerators of tomorrow be run like the ever increasing robotic assembly plants of today. How is the role of the operator changing in this new environment

  13. Radiation-induced cancers in man

    Energy Technology Data Exchange (ETDEWEB)

    Hirose, F [Hiroshima Univ. (Japan). Research Inst. for Nuclear Medicine and Biology

    1978-07-01

    Radiation-induced cancers in man were divided into three groups, a group in which cancers occurred after atomic bomb exposure, a group in which cancers occurred in radiologists and other medical specialists, and a group in which cancers occurred after exposure to diagnostic radiation, and they were summarized. In atomic bomb survivors leukemia, thyroid cancer, salivary gland cancer, lung cancer, and breast cancer occurred so frequently. In addition to them, mortality ratios by malignant lymphoma, stomach cancer, esophageal cancer, and by cancer of urinary tract were increased. The incidence of leukemia was decreased in those who treated radiation owing to the development of the protection of occupational exposure, and the incidence of radiation-induced cancers was decreased in patients owing to the improvement of therapy. However, a new problem has arisen as to the occurrence of cancers after medical exposure, such as various histological types of cancers after the treatment of skin diseases on the head, and breast cancer after the treatment of pneumothorax. Dose-to-effect relation, hereditary factors, effect of age, immunological influences and endocrine actions were also studied in each radiation-induced cancer.

  14. Asymptomatic young man with an incidental murmur.

    Science.gov (United States)

    Shojaeifard, Maryam; Pouraliakbar, Hamid Reza; Houshmand, Golnaz

    2018-05-31

    A 32-year old man was referred to our institution for transthoracic echocardiography (TTE) following detection of an incidental murmur on physical examination before blood donation. He was asymptomatic with no significant medical history. Physical examination revealed dual heart sounds with a grade II/VI systolic murmur heard in the left sternal border. An ECG was in normal sinus rhythm. TTE was performed (figure 1A-C, online supplementary videos 1-4) followed by cardiac CT angiography (CTA) (figure 1D,E).heartjnl;heartjnl-2018-313223v1/F1F1F1Figure 1(A) Transthoracic echocardiography, parasternal left ventricular long axis view. (B) Colour Doppler of modified short axis in the mid-left ventricular level. (C) Doppler flow velocity profile. (D) Cardiac CT angiography (CTA) sagittal reconstruction. (E) Three-dimensional CTA reconstruction of the heart. What is the diagnosis?Pericardial cyst.Ventricular septal defect.Kawasaki.Anomalous left coronary artery from pulmonary artery (ALCAPA). © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  15. tu ša šarri. La « loi du roi »dans la Babylonie achéménide et séleucide dātu ša šarri, The “Law of the King” in Achaemenid and Seleucid Babylonia

    Directory of Open Access Journals (Sweden)

    Sophie Démare-Lafont

    2009-06-01

    Full Text Available Cet article examine le champ sémantique de l’expression dātu ša šarri, « loi du roi », formée sur un terme d’origine vieux-perse (data. La dizaine d’occurrences d’époques achéménide et séleucide montre que la « loi du roi »désigne un mode d’élaboration de la norme issu de la pratique judiciaire du souverain, progressivement compilée pour former un corps de règles invoquées dans les contrats. Ce procédé de création de la loi et de fabrication des recueils législatifs rappelle celui du rescrit romain.This article investigates the meaning of the formula dātu ša šarri, “law of the king”, using the akkadian dātu based on the old Persian word dāta. The ten Achaemenid and Seleucid occurrences of this formula suggest a process of creation of legal rules comparable to the Roman rescript: the legal standard dātu ša šarri derives from the judicial practice of the king, whose decisions were progressively compiled in order to create a body of regulations which were invoked in contracts.

  16. SOCIO-EDUCATIONAL ASPECTS OF THE WORKING MAN FORMATION.

    Directory of Open Access Journals (Sweden)

    Y. F. Zeyer

    2013-01-01

    Full Text Available The paper analyzes a new for the Russian anthropology concept of the «working man», introduced in the Urals along with the propagation of a social and political movement «For the Working Man Protection»; the semantic content of the «man» and «labor» notions being observed as well as the process and problems of the working man formation in the modern world.The author emphasizes the asymmetry of the socio-economic and vocational educational infrastructure, along with the contradictions between the labor market demands for the technical and technological profile workers and the existing educational qualification structure of vocational schools.In author's opinion, the disorganization of labor training in comprehensive school and deficiencies of vocational education hinder the process of the industrial working man formation. The professional orientation system is criticized for being unable to meet the demands of modern economy and provide the young people with the adequate concept of the working career.For overcoming the above problems affecting the working man formation, the paper recommends modernization of the labor training system in comprehensive schools, reformation of vocational training, and renovation of professional orientation system. The special emphasis is given to the continuing training of the working man

  17. Koherentas kustības uztvere skolas vecuma bērniem ar sašaurinātu vizuālās uztveres lauku

    OpenAIRE

    Gritāne, Andželika

    2017-01-01

    Maģistra darbs tika uzrakstīts latviešu valodā uz 40 lapām, darbs satur 24 attēlus, 8 tabulas un satur 28 atsauces uz literatūras avotiem. Darba mērķis: Noteikt koherentas kustības slieksni skolas vecuma bērniem ar sašaurinātu vizuālās uzmanības lauku. Metodika: Dalībnieki tika iedalīti divās grupās balstoties un nevārda atpazīšanas testa rezultātiem – grupa ar sašaurinātu vizuālās uztveres lauku un grupa ar attīstībai atbilstošu vizuālās uztveres lauka lielumu. Abu grupu dalībniekiem tika n...

  18. Reference man models based on normal data from human populations

    International Nuclear Information System (INIS)

    Tanaka, Gi-ichiro; Kawamura, Hisao

    2000-01-01

    Quantitative description of the physical, and metabolic parameters of the human body is the very basic for internal dosimetry. Compilation of anatomical and other types of data Asian populations for internal (and external) dosimetry is of grate significance because of the potential spread of nuclear energy use in the Asian region and the major contribution of the region to the world population (about 58%). It has been observed that some differences exist for habitat, race, body sizes and pattern of food consumption. In the early stage of revision of ICRP Reference man by the Task Group, Characteristics of the human body of non-European populations received considerable attention as well as those of the European populations of different sexes and ages. In this context, an IAEA-RCA Co-ordinated Research Program on Compilation of Anatomical, Physiological and Metabolic Characteristics for a Reference Asian Man endorsed. In later stages of reference Man revision, anatomical data for Asians was discusses together with those of European populations, presumably due to ICRP's decision of unanimous use of the Reference Man for radiation protection. Reference man models for adults and 15, 10, 5, 1, 0 year-old males and females of Asian populations were developed for use in internal and external dosimetry. Based on the concept of ICRP Reference Man (Publication 23), the reference values were derived from the normal organ mass data for Japanese and statistical data on the physique and nutrition of Japanese and Chinese. Also incorporated were variations in physical measurements, as observed in the above mentioned IAEA-RCA Co-ordinated Research Program. The work was partly carried out within the activities of the ICRP Task Group on Reference Man. The weight of the skeleton was adjusted following the revised values in Publication 70. This paper will report basic shared and non-shared characteristics of Reference Man' for Asians and ICRP Reference Man. (author)

  19. The new 6 MW industrial gas turbine from MAN; Die neue 6 MW Industriegasturbine von MAN

    Energy Technology Data Exchange (ETDEWEB)

    Beukenberg, M.; Wiedermann, A.; Orth, U.; Aschenbruck, E.; Reiss, F. [MAN Diesel und Turbo SE, Oberhausen (Germany)

    2010-07-01

    The development of a completely new series of gas turbines requires significant capital, resources and know-how. MAN Diesel and Turbo strategically decided to create a small gas turbine in the 6 MW-class. The construction of the Gas Turbine has been on the basis of opportunities in current and future markets and the positioning of the competition, this has determined the characteristics and technical parameters which have been optimised in the 6 MW design. The construction uses extremely high precision engineering so that the assembly of sub-components to modules is a smooth flowing process and can guarantee the high standards both quality and performance which MAN Diesel and Turbo are operating to. The individual components must be tested and thoroughly validated many months before actual assembly of the first machine. These include in particular the compressor of the gas turbine and the combustion chamber. The combustion system required special attention, since the emissions are strongly focused to satisfy stringent environmental requirements. The planned tests are a prerequisite for the construction of such a prototype and must be successfully completed before the Gas Turbine will be accepted into service. (orig.)

  20. A Rich Man, Poor Man Story of S-Adenosylmethionine and Cobalamin Revisited.

    Science.gov (United States)

    Bridwell-Rabb, Jennifer; Grell, Tsehai A J; Drennan, Catherine L

    2018-06-20

    S-adenosylmethionine (AdoMet) has been referred to as both "a poor man's adenosylcobalamin (AdoCbl)" and "a rich man's AdoCbl," but today, with the ever-increasing number of functions attributed to each cofactor, both appear equally rich and surprising. The recent characterization of an organometallic species in an AdoMet radical enzyme suggests that the line that differentiates them in nature will be constantly challenged. Here, we compare and contrast AdoMet and cobalamin (Cbl) and consider why Cbl-dependent AdoMet radical enzymes require two cofactors that are so similar in their reactivity. We further carry out structural comparisons employing the recently determined crystal structure of oxetanocin-A biosynthetic enzyme OxsB, the first three-dimensional structural data on a Cbl-dependent AdoMet radical enzyme. We find that the structural motifs responsible for housing the AdoMet radical machinery are largely conserved, whereas the motifs responsible for binding additional cofactors are much more varied.

  1. "Det man hører, er man selv" - musik og identitet set gennem musikforskningens briller

    Directory of Open Access Journals (Sweden)

    Lars Ole Bonde

    2015-11-01

    Full Text Available ”Det man hører, er man selv” er Danmarks Radios P3s yderst velkendte slogan. Det dukkede op i begyndelsen af (2000’erne som opfindsom og populær afspejling af en moderne forståelse af den rolle musik og medieforbrug spiller for den voksne dansker. Denne artikel handler ikke om P3 som musikkanal, men går bag om det populære slogan og undersøger hvordan musik og identitet spiller sammen. Hvilke (musikpsykologiske teorier belyser musikkens rolle i identitetsdannelsen? Hvordan forskes der i emnet, og hvilke resultater kan der peges på? Forskningen dokumenterer bl.a., at musik bruges aktivt af mange mennesker som en ressource til at konstruere selv-identitet og gruppe-identitet, og til at skabe, opretholde og regulere en mangfoldighed af følelser. Denne oversigtsartikel giver via præsentation af udvalgte teorier og konkrete undersøgelser en bred introduktion til emnet og viser, hvordan musikforskere gennem arbejde med interviews, dagbøger og (musikalske selvbiografier samt feltarbejde kan beskrive musik som en ofte meget vigtig brik i identitetsdannelsen.

  2. Queer encounters between Iron Man and Chinese boys' love fandom

    Directory of Open Access Journals (Sweden)

    John Wei

    2014-09-01

    Full Text Available Superhero fan fiction is increasingly popular in the Chinese boys' love (BL community. An exploration of the fan fic Gangtiexia: Zhongdu Yilai (Iron Man: Overly attached investigates how the Hollywood cultural icon Iron Man/Tony Stark is reimagined in Chinese BL culture and to what degree this kind of rendition both echoes and extends as well as challenges and deviates from our current insights into BL fandoms. Through the lenses of queerness and technological human transformation, I explore the fresh contribution of Iron Man fan fiction to both local BL cultures and global superhero fandoms.

  3. Graphic man-machine interface applied to nuclear reactor designs

    International Nuclear Information System (INIS)

    Pereira, Claudio M.N.A; Mol, Antonio Carlos A.

    1999-01-01

    The Man-Machine Interfaces have been of interest of many researchers in the area of nuclear human factors engineering, principally applied to monitoring systems. The clarity of information provides best adaptation of the men to the machine. This work proposes the development of a Graphic Man-Machine Interface applied to nuclear reactor designs as a tool to optimize them. Here is present a prototype of a graphic man-machine interface for the Hammer code developed for PC under the Windows environment. The results of its application are commented. (author)

  4. Dgp71WD is required for the assembly of the acentrosomal Meiosis I spindle, and is not a general targeting factor for the γ-TuRC

    Directory of Open Access Journals (Sweden)

    Richard F. Reschen

    2012-03-01

    Dgp71WD/Nedd1 proteins are essential for mitotic spindle formation. In human cells, Nedd1 targets γ-tubulin to both centrosomes and spindles, but in other organisms the function of Dgp71WD/Nedd1 is less clear. In Drosophila cells, Dgp71WD plays a major part in targeting γ-tubulin to spindles, but not centrosomes, while in Xenopus egg extracts, Nedd1 acts as a more general microtubule (MT organiser that can function independently of γ-tubulin. The interpretation of these studies, however, is complicated by the fact that some residual Dgp71WD/Nedd1 is likely present in the cells/extracts analysed. Here we generate a Dgp71WD null mutant lacking all but the last 12 nucleotides of coding sequence. The complete loss of Dgp71WD has no quantifiable effect on γ-tubulin or Centrosomin recruitment to the centrosome in larval brain cells. The recruitment of γ-tubulin to spindle MTs, however, is severely impaired, and spindle MT density is reduced in a manner that is indistinguishable from cells lacking Augmin or γ-TuRC function. In contrast, the absence of Dgp71WD leads to defects in the assembly of the acentrosomal female Meiosis I spindle that are more severe than those seen in Augmin or γ-TuRC mutants, indicating that Dgp71WD has additional functions that are independent of these complexes in oocytes. Moreover, the localisation of bicoid RNA during oogenesis, which requires γ-TuRC function, is unperturbed in Dgp71WD120 mutants. Thus, Dgp71WD is not simply a general cofactor required for γ-TuRC and/or Augmin targeting, and it appears to have a crucial role independent of these complexes in the acentrosomal Meiosis I spindle.

  5. Heterologous expression of a plastid EF-Tu reduces protein thermal aggregation and enhances CO2 fixation in wheat (Triticum aestivum) following heat stress.

    Science.gov (United States)

    Fu, Jianming; Momcilović, Ivana; Clemente, Thomas E; Nersesian, Natalya; Trick, Harold N; Ristic, Zoran

    2008-10-01

    Heat stress is a major constraint to wheat production and negatively impacts grain quality, causing tremendous economic losses, and may become a more troublesome factor due to global warming. At the cellular level, heat stress causes denaturation and aggregation of proteins and injury to membranes leading to alterations in metabolic fluxes. Protein aggregation is irreversible, and protection of proteins from thermal aggregation is a strategy a cell uses to tolerate heat stress. Here we report on the development of transgenic wheat (Triticum aestivum) events, expressing a maize gene coding for plastidal protein synthesis elongation factor (EF-Tu), which, compared to non-transgenic plants, display reduced thermal aggregation of leaf proteins, reduced heat injury to photosynthetic membranes (thylakoids), and enhanced rate of CO(2) fixation after exposure to heat stress. The results support the concept that EF-Tu ameliorates negative effects of heat stress by acting as a molecular chaperone. This is the first demonstration of the introduction of a plastidal EF-Tu in plants that leads to protection against heat injury and enhanced photosynthesis after heat stress. This is also the first demonstration that a gene other than HSP gene can be used for improvement of heat tolerance and that the improvement is possible in a species that has a complex genome, hexaploid wheat. The results strongly suggest that heat tolerance of wheat, and possibly other crop plants, can be improved by modulating expression of plastidal EF-Tu and/or by selection of genotypes with increased endogenous levels of this protein.

  6. Effects of mineral water from spring 3 in Băile Tuşnad on experimentally induced alcoholic liver disease

    Directory of Open Access Journals (Sweden)

    Gabriela Dogaru

    2017-05-01

    Full Text Available Chronic alcohol consumption leads to the development of specific disorders, particularly of the liver. In this study, we aimed to investigate by optical microscopy the hepatic changes occurring after administration of ethyl alcohol for 70 days to Wistar rats, as well as the curative effect of mineral water from spring 3 in Băile Tuşnad administered for 50 days after completion of ethyl alcohol administration. Liver fragments were harvested and histologically processed by paraffin embedding and stained with Goldner’s trichrome method. After the first 70 days of the experiment, in the liver parenchyma, fat loading of hepatocytes and mild perivascular fibrosis were identified. After another 50 days, during which some of the rats drank tap water, the pathological evolution did not seem to stop, but on the contrary, a slight aggravation could be observed, while in rats drinking Tuşnad mineral water there was an arrest of evolution and a slight regression of the described aspects. This study evidences the curative effect of mineral water from spring 3 in Băile Tuşnad on alcoholic liver disease.

  7. Ion Inculetz- Political man and scientist

    Science.gov (United States)

    Gaina, A.; Ionescu-Pallas, N. I.

    1993-06-01

    It is well known, that the president of the first Moldavian Parliament in 1918 was Ion Inculetz (borne on 5 april, 1884, Rezeni vill., Lapusna county, Basarabia - died on 19 november 1940, Bucharest, regraved in Barnova, near Iasi). On 24 January 1918 this Parliament claimed the independence of Basarabia from the Russia (The Democratic Republic of Moldova). On 27 march of the same year in a solennele session the Parliament claimed "The Democratic Republic of Moldova (Basarabia) in its borders between Prut, Dniester rivers, Black Sea, and old borders with Austria, rupted by Russia more than one hundred years from the body of old Moldova, due to the historical right and due to the right of the selfdetermination of peoples, is unifying forever with She's mother Romania ". After the Unification Ion Inculetz activated as representative of Basarabia in the Romanian Parliament. He was a man of democratic views, a partisan of social-democracy in Russia, as well as in Romania after the unification. The progress of peoples was one of His main political goals. It is less known, however, that Inculetz was a remarkable physicist. This is the subject of the conference. After the finish of the secondary studies in Chisinau, He entered to Jur'ev (actually Tartu- Estonia) University Medecine Department, but after one year of studies He moved to Sankt-Petersburg Imperial University, where He specialized in physics and mathematics. After the finish of the Physical Mathematical Department he became private-docent (Associate Professor). Concomittantly He taught methematics at one of the comercial schhols in Sankt Petersburg. In the same time he was a Scientific Secretary of the journal "Nauchnoie Obozrenie" ("Scientific Review") and a researcher at the Meteorological Observatory in Sankt-Petersburg (since 1914). Since 1912 till 1917 He published a series of papers in the fields of physics and meteorology, particularly concerned to anodic rays, Krooks tubes, radiactivity, Doppler effect

  8. Moon manned missions radiation safety analysis

    Science.gov (United States)

    Tripathi, R. K.; Wilson, J. W.; de Anlelis, G.; Badavi, F. F.

    An analysis is performed on the radiation environment found on the surface of the Moon, and applied to different possible lunar base mission scenarios. An optimization technique has been used to obtain mission scenarios minimizing the astronaut radiation exposure and at the same time controlling the effect of shielding, in terms of mass addition and material choice, as a mission cost driver. The optimization process has been realized through minimization of mass along all phases of a mission scenario, in terms of time frame (dates, transfer time length and trajectory, radiation environment), equipment (vehicles, in terms of shape, volume, onboard material choice, size and structure), location (if in space, on the surface, inside or outside a certain habitats), crew characteristics (number, gender, age, tasks) and performance required (spacecraft and habitat volumes), radiation exposure annual and career limit constraint (from NCRP 132), and implementation of the ALARA principle (shelter from the occurrence of Solar Particle Events). On the lunar surface the most important contribution to radiation exposure is given by background Galactic Cosmic Rays (GCR) particles, mostly protons, alpha particles, and some heavy ions, and by locally induced particles, mostly neutrons, created by the interaction between GCR and surface material and emerging from below the surface due to backscattering processes. In this environment manned habitats are to host future crews involved in the construction and/or in the utilization of moon based infrastructure. Three different kinds of lunar missions are considered in the analysis, Moon Base Construction Phase, during which astronauts are on the surface just to build an outpost for future resident crews, Moon Base Outpost Phase, during which astronaut crews are resident but continuing exploration and installation activities, and Moon Base Routine Phase, with long-term shifting resident crews. In each scenario various kinds of habitats

  9. Emmonsia helica Infection in HIV-Infected Man, California, USA.

    Science.gov (United States)

    Rofael, Martin; Schwartz, Ilan S; Sigler, Lynne; Kong, Li K; Nelson, Nicholas

    2018-01-01

    Emmonsia-like fungi have rarely been reported from North America. We report a fatal case of E. helica infection in a man with advanced HIV infection from California, USA, who had progressive respiratory failure and a brain abscess.

  10. Power system technologies for the manned Mars mission

    International Nuclear Information System (INIS)

    Bents, D.; Patterson, M.J.; Berkopec, F.; Myers, I.; Presler, A.

    1986-01-01

    The high impulse of electric propulsion makes it an attractive option for manned interplanetary missions such as a manned mission to Mars. This option is, however, dependent on the availability of high energy sources for propulsive power in addition to that required for the manned interplanetary transit vehicle. Two power system technologies are presented: nuclear and solar. The ion thruster technology for the interplanetary transit vehicle is described for a typical mission. The power management and distribution system components required for such a mission must be further developed beyond today's technology status. High voltage-high current technology advancements must be achieved. These advancements are described. In addition, large amounts of waste heat must be rejected to the space environment by the thermal management system. Advanced concepts such as the liquid droplet radiator are discussed as possible candidates for the manned Mars mission. These thermal management technologies have great potential for significant weight reductions over the more conventional systems

  11. IMPACT OF SCIENCE AND SCIENTIFIC WORLDVIEW ON MAN: A ...

    African Journals Online (AJOL)

    Ike Odimegwu

    outlines, therefore, the impact of science on man has moved in three stages: Physical .... of appreciation, understanding and action proper to the scientific mind. It refers ...... This has excluded chain reactions of the warheads that will follow not ...

  12. Biology as a Study of Man and Society

    Science.gov (United States)

    Hurd, Paul DeHart

    1971-01-01

    Biology ought to be taught within the context of human culture; "man" can be the "type animal." Consideration should be given to questions of race, population, food resources, environmental quality, intelligence, genetic engineering, and organ transplants. (AL)

  13. Man and Cosmos from the Christian Theology perspective

    Directory of Open Access Journals (Sweden)

    Marin BUGIULESCU

    2017-06-01

    Full Text Available The purpose of this paper is to analyse the theological reflection on the relationship between man and cosmos. The origin of the world and man is connected to God; God is the Creator and consequently the Author of them both. Unlike dualistic materialistic thinking, according to the Christian conception the whole cosmos is created by God. In search for the cosmos an important chapter was granted for man, considered to be a synthesis of the world. Man, from the theological perspective, is the personal, rational, free, and speaking being that has – through the image of God according to which he has been created –, the tension after perfection. But it pertains exclusively to the relationship with Christ in the light of Whom he really knows himself, and by knowing himself he recognizes the infinite beauty of the Archetype. This is the existential-theological truth, which the content of this paper emphasizes, according to the Bible and patristic teaching.

  14. the unsung earth: man's regeneration and rediscovery of the earth

    African Journals Online (AJOL)

    User

    position of comfortable apathy with a topic that has much relevance in ... towards man's selfishness and reckless defiance of nature that Corona channels and .... tap into their technological appliances, turn to their forgotten God more in anger ...

  15. Conference on Manned Systems Design : New Methods and Equipment

    CERN Document Server

    Kraiss, K-F

    1981-01-01

    This volume contains the proceedings of a conference held in Freiburg, West Germany, September 22-25, 1980, entitled "Manned Systems Design, New Methods and Equipment". The conference was sponsored by the Special Programme Panel on Human Factors of the Scientific Affairs Division of NATO, and supported by Panel VIII, AC/243, on "Human and Biomedical Sciences". Their sponsorship and support are gratefully acknowledged. The contributions in the book are grouped according to the main themes of the conference with special emphasis on analytical approaches, measurement of performance, and simulator design and evaluat ion. The design of manned systems covers many and highly diversified areas. Therefore, a conference under the general title of "Manned Systems Design" is rather ambitious in itself. However, scientists and engineers engaged in the design of manned systems very often are confronted with problems that can be solved only by having several disciplines working together. So it was felt that knowledge about ...

  16. Agter elke man: Onderweg na inklusiewe taalgebruik in die ...

    African Journals Online (AJOL)

    31 Mei 2016 ... Agter elke man: Onderweg na inklusiewe taalgebruik in die Afrikaanse kerklied .... reaksie van gemeentelede en opmerkings op sosiale media ..... and unstable masculinity/ies of Jesus Christ and the multiple and changing ...

  17. Branding: A Strategy for Manning an All-Volunteer Army

    National Research Council Canada - National Science Library

    Keeter, John M

    2008-01-01

    .... The ability to man the Army and realize the vision of a "quality" force is challenged not only by the impacts of a protracted war on the attitudes of the youth, and their influencers, but also...

  18. Manned Mission Space Exploration Utilizing a Flexible Universal Module

    Science.gov (United States)

    Humphries, P.; Barez, F.; Gowda, A.

    2018-02-01

    The proposed ASMS, Inc. "Flexible Universal Module" is in support of NASA's Deep Space Gateway project. The Flexible Universal Module provides a possible habitation or manufacturing environment in support of Manned Mission for Space Exploration.

  19. Modelling of glucose-insulin-glucagon pharmacodynamics in man

    DEFF Research Database (Denmark)

    Wendt, Sabrina Lyngbye; Møller, Jan Kloppenborg; Haidar, A.

    The purpose is to build a simulation model of the glucoregulatory system in man. We estimate individual human parameters of a physiological glucose-insulin-glucagon model. We report posterior probability distributions and correlations of model parameters....

  20. Meticillin-sensitive Staphylococcus aureus costochondritis in a healthy man.

    LENUS (Irish Health Repository)

    Mohammad, Ausaf F

    2009-12-01

    A 54-year-old previously healthy white man presented to hospital with fever, right parasternal pain and swelling over the right second and third costochondral joints. The symptoms had developed 1 week earlier.

  1. Global Man-made Impervious Surface (GMIS) Dataset From Landsat

    Data.gov (United States)

    National Aeronautics and Space Administration — The Global Man-made Impervious Surface (GMIS) Dataset From Landsat consists of global estimates of fractional impervious cover derived from the Global Land Survey...

  2. Man-machine interfaces analysis system based on computer simulation

    International Nuclear Information System (INIS)

    Chen Xiaoming; Gao Zuying; Zhou Zhiwei; Zhao Bingquan

    2004-01-01

    The paper depicts a software assessment system, Dynamic Interaction Analysis Support (DIAS), based on computer simulation technology for man-machine interfaces (MMI) of a control room. It employs a computer to simulate the operation procedures of operations on man-machine interfaces in a control room, provides quantified assessment, and at the same time carries out analysis on operational error rate of operators by means of techniques for human error rate prediction. The problems of placing man-machine interfaces in a control room and of arranging instruments can be detected from simulation results. DIAS system can provide good technical supports to the design and improvement of man-machine interfaces of the main control room of a nuclear power plant

  3. Magnetoshell Aerocapture for Manned Missions and Planetary Deep Space Orbiters

    Data.gov (United States)

    National Aeronautics and Space Administration — It is clear from past mission studies that a manned Mars mission, as well as deep space planetary orbiters will require aerobraking and aerocapture which use...

  4. InMotion : hybrid race car, beating F1 at LeMans

    NARCIS (Netherlands)

    Jacob, J.; Colin Navarrete, J.A.; Montemayor, H.; Sepac, D.; Trinh, H.D.; Voorderhake, S.F.; Zidkova, P.; Paulides, J.J.H.; Borisavljevic, A.; Lomonova, E.

    2013-01-01

    This paper presents the design of a hybrid electric powertrain for the InMotion IM01 race car. InMotion is a multidisciplinary project group of experienced master students, PhD students, and professors from Eindhoven University of Technology (TU/e). The authors of this paper were involved in the

  5. COST Action TU1208 - Working Group 3 - Electromagnetic modelling, inversion, imaging and data-processing techniques for Ground Penetrating Radar

    Science.gov (United States)

    Pajewski, Lara; Giannopoulos, Antonios; Sesnic, Silvestar; Randazzo, Andrea; Lambot, Sébastien; Benedetto, Francesco; Economou, Nikos

    2017-04-01

    This work aims at presenting the main results achieved by Working Group (WG) 3 "Electromagnetic methods for near-field scattering problems by buried structures; data processing techniques" of the COST (European COoperation in Science and Technology) Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar" (www.GPRadar.eu, www.cost.eu). The main objective of the Action, started in April 2013 and ending in October 2017, is to exchange and increase scientific-technical knowledge and experience of Ground Penetrating Radar (GPR) techniques in civil engineering, whilst promoting in Europe the effective use of this safe non-destructive technique. The Action involves more than 150 Institutions from 28 COST Countries, a Cooperating State, 6 Near Neighbour Countries and 6 International Partner Countries. Among the most interesting achievements of WG3, we wish to mention the following ones: (i) A new open-source version of the finite-difference time-domain simulator gprMax was developed and released. The new gprMax is written in Python and includes many advanced features such as anisotropic and dispersive-material modelling, building of realistic heterogeneous objects with rough surfaces, built-in libraries of antenna models, optimisation of parameters based on Taguchi's method - and more. (ii) A new freeware CAD was developed and released, for the construction of two-dimensional gprMax models. This tool also includes scripts easing the execution of gprMax on multi-core machines or network of computers and scripts for a basic plotting of gprMax results. (iii) A series of interesting freeware codes were developed will be released by the end of the Action, implementing differential and integral forward-scattering methods, for the solution of simple electromagnetic problems by buried objects. (iv) An open database of synthetic and experimental GPR radargrams was created, in cooperation with WG2. The idea behind this initiative is to give researchers the

  6. [Knowledge of Man Returns: Some Considerations on Spirituality and Resilience].

    Science.gov (United States)

    Kumakura, Nobuhiro

    2015-01-01

    Over the last decade,"spirituality" and "resilience" have jointly become a topic in psychiatry. The aim of this paper is to discuss the future of psychiatry suggested by this topic. It may be related to what Jaspers, K. called "Knowledge of Man (die Erkenntnis des Menschen)". Knowledge of man in psychiatry can be learned only through clinical experince: e. g., clinical observations and case studies. Modern academic psychiatry seems to be suffering a loss of knowledge of man, which returns periodically in clinical practice. Hence, I will call the re-discovery of the topic in psychiatry as "Return of Man". Since WW II, there have been three eras in which psychiatrists showed deep concern regarding knowledge of man. Firstly, psychopathology and psychotherapy widely developed, when the destructive impulses of mankind were revealed in the nuclear weapons of WW II. Secondly, in the 1970's, the reforms of psychiatric services and legal systems took place somewhat successfully, when social reforms were concerns of the younger generations. Lastly, over the last decade, the topic again returned as spirituality and resilience, when scientists seemed to be powerless in the aftermath of the West Japan Earthquake. Regarding the definition of health made by the WHO in 1946, I further discuss that "Return of Man" in psychiatry is the necessary dynamism between negative and positive health, or between disease control and health promotion. There is an underlying dynamism between "Knowledge of Man" and natural sciences, which is constantly changing. So long as any theory can exist only as a part of dynamism, the Return of Man may re-surface whenever clinical theories do not fit with clinical realities.

  7. Manned Mars mission communication and data management systems

    Science.gov (United States)

    White, Ronald E.

    1986-01-01

    A manned Mars mission will involve a small crew and many complex tasks. The productivity of the crew and the entire mission will depend significantly on effective automation of these tasks and the ease with which the crew can interface with them. The technology to support a manned Mars mission is available today; however, evolving software and electronic technology are enabling many interesting possibilities for increasing productivity and safety while reducing life cycle cost. Some of these advanced technologies are identified.

  8. Trust between man and machine in a teleoperation system

    International Nuclear Information System (INIS)

    Dassonville, I.; Jolly, D.; Desodt, A.M.

    1996-01-01

    The work we present deals with the trust of man in a teleoperation system. Trust is important because it is linked to stress which modifies human reliability. We are trying to quantify trust. In this paper, we'll present the theory of trust in relationships, and its extension for a man-machine system. Then, we explain the links between trust and human reliability. Then, we introduce our experimental process and the first results concerning selfconfidence

  9. Godt at man slipper for 2296 kommaer i "Butcher's Crossing"

    DEFF Research Database (Denmark)

    Davidsen-Nielsen, Niels

    2015-01-01

    Eftertanken. Det vækker til eftertanke at sproget i " Butcher's Crossing" takket være kommateringen flyder let derudad. Man burde have brugt samme kommatering i John Williams' første roman på dansk, " Stoner".......Eftertanken. Det vækker til eftertanke at sproget i " Butcher's Crossing" takket være kommateringen flyder let derudad. Man burde have brugt samme kommatering i John Williams' første roman på dansk, " Stoner"....

  10. 137Cs in man due to nuclear fallout

    International Nuclear Information System (INIS)

    Poulheim, K.F.

    1981-01-01

    137 Cs has been determined in man with the aid of a whole-body counter. It is shown that the specific 137 Cs content (as related to the potassium content in man) continuously decreased from 1965 through 1974. After a slight increase in 1975, possibly caused by a Chinese atmospheric nuclear test in June 1974, the 137 Cs content again decreased in the following years. (author)

  11. COST Action TU1208 - Working Group 1 - Design and realisation of Ground Penetrating Radar equipment for civil engineering applications

    Science.gov (United States)

    Pajewski, Lara; Benedetto, Andrea; D'Amico, Sebastiano; Ferrara, Vincenzo; Frezza, Fabrizio; Persico, Raffaele; Tosti, Fabio

    2017-04-01

    This work aims at presenting the main results achieved by Working Group (WG) 1 "Novel Ground Penetrating Radar instrumentation" of the COST (European COoperation in Science and Technology) Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar" (www.cost.eu, www.GPRadar.eu). The principal goal of the Action, which started in April 2013 and is ending in October 2017, is to exchange and increase scientific-technical knowledge and experience of Ground Penetrating Radar techniques in civil engineering, whilst promoting throughout Europe the effective use of this safe non-destructive technique. The Action involves more than 300 Members from 28 COST Countries, a Cooperating State, 6 Near Neighbour Countries and 6 International Partner Countries. The most interesting achievements of WG1 include: 1. The state of the art on GPR systems and antennas was composed; merits and limits of current GPR systems in civil engineering applications were highlighted and open issues were identified. 2. The Action investigated the new challenge of inferring mechanical (strength and deformation) properties of flexible pavement from electromagnetic data. A semi-empirical method was developed by an Italian research team and tested over an Italian test site: a good agreement was found between the values measured by using a light falling weight deflectometer (LFWD) and the values estimated by using the proposed semi-empirical method, thereby showing great promises for large-scale mechanical inspections of pavements using GPR. Subsequently, the method was tested on a real scale, on an Italian road in the countryside: again, a good agreement between LFWD and GPR data was achieved. As a third step, the method was tested at larger scale, over three different road sections within the districts of Madrid and Guadalajara, in Spain: GPR surveys were carried out at the speed of traffic for a total of 39 kilometers, approximately; results were collected by using different GPR antennas

  12. IMPLEMENTASI MANAJEMEN PERUBAHAN DI MAN 3 PALEMBANG SUMATERA SELATAN

    Directory of Open Access Journals (Sweden)

    Afriantoni Imran

    2014-11-01

    Full Text Available AbstractMadrasah Aliyah Negeri (MAN 3 Palembang is unique enough to be studied because since inception of Islamic religion teacher education institutions. The results of this study found that type of leadership visoner is owned by head of Man 3 Palembang oriented management of change and continues over time. Visionary leadership is the key. Head of MAN 3 Palembang has been able to create, formulate, communicate, socialize, transform, and implement the ideal thoughts coming from him and the result of social interaction between members of organization and stakeholders that are believed to achieve ideals of organization in the future. In addition, management of change has been initiated through an internal analysis of the organization by identifying four areas, namely services, finance, human resources and facilities in order to discover the strengths and weaknesses internal to the organization. All of this has been the commitment of all personnel MAN 3 Palembang to achieve my goals and success. Lastly, head of MAN 3 Palembang has been able to implement management changes, so that the organization built quality improvement-oriented leadership, teacher quality, school programs, students' final exam results, student achievement and strong school culture. Keywords: implementation, management of change, MAN 3 Palembang

  13. Physical characteristics of the Japanese in relation to reference man

    International Nuclear Information System (INIS)

    Tanaka, G.-i.; Kawamura, H.; Nomura, E.

    1980-01-01

    Quantitative description of physical and other characteristics of the human body provides basic data for the estimation of radiation risk and the establishment of dose equivalent in line with the International Commission on Radiological Protection recommendations. ICRP Reference Man is based essentially on data reported on populations in rather limited areas in the world although Committee 2 of ICRP concedes that ''it is neither feasible nor necessary to specify Reference Man as representative of a well-defined population group''. ICRP Reference Man is not necessarily based on the most recent available data. In order to be more realistic and quantitative in dose equivalent estimation in Japan, it is necessary to consider populations which are largely different from those of European and North American countries in physical dimensions and other aspects. Therefore, standard or reference values of mass and size of organs, body and organ content and metabolic parameters of some elements have been studied. These are compared with the values of ICRP Reference Man authorized up to now, with the intention of establishing ''Reference Japanese Man'' and contributing to the improvement of models of man used in radiation protection. Dose equivalent commitment and annual limit of intake have been calculated using the obtained data for the general population in Japan,for some nuclides. (H.K.)

  14. Emblem for the third manned Skylab mission - Skylab 4

    Science.gov (United States)

    1973-01-01

    This is the emblem for the third manned Skylab mission. It will be a mission of up to 56 days. The symbols in the patch refer to the three major areas of investigation proposed in the mission. The tree represents man's natural environment and relates directly to the Skylab mission objectives of advancing the study of Earth resources. The hydrogen atom, as the basic building block of the universe, represents man's exploration of the physical world, his application of knowledge, and his development of technology. Since the Sun is composed primarily of hydrogen, it is appropriate that the symbol refers to the solar physics mission objectives. The human silhouette represents mankind and the human capacity to direct technology with a wisdom tempered by regard for his natural environment. It also directly relates to the Skylab medical studies of man himself. The rainbow, adopted from the Biblical story of the flood, symbolizes the promise that is offered man. It embraces man and extends to t

  15. 40Ar/39Ar Geochronology of Supergene K-bearing Sulfate Minerals: Cenozoic Continental Weathering, Landscape Evolution and Paleoclimates in the Tu-Ha Basin, Northwestern China

    Science.gov (United States)

    Yang, J.; Zheng, D.; Chen, W.; Hough, B.; Qiu, H.; Wang, W.; Wu, Y.; Yang, L.

    2017-12-01

    40Ar/39Ar incremental-heating analyses of supergene jarosite and yavapaiite from three weathering profiles at the Hongshan, Liuhuangshan, and Caihuagou deposits in the Tu-Ha Basin, China, were carried out to provide numerical constraints on the timing and duration of weathering and derive insights into local paleoclimatic and landscape evolution. Well-constrained plateau ages and best-fitting inverse isochrons have been obtained for 11 samples, yield 40Ar/39Ar ages ranging from 33.3±0.5 Ma to 3.3±0.4 Ma (1σ). Our 40Ar/39Ar ages, combined with the published ages, indicate that the high elevations sites hosting the most complete and complex weathering profiles present. The presence of ancient weathering ages in current outcrop in the Tu-Ha Basin suggests that denudation was not homogeneous, and the landscape evolution follow a scarp retreat model. These geochronological results suggest that a protracted history of weathering and supergene enrichment and, by inference, arid-semiarid climate (with at least a moderate amount of precipitation (>10 cm/y)) favorable to intense chemical weathering emerged at 33.3 Ma, 27.7-23.3 Ma, and 16.4-14.7 Ma, and prevailed from 11-7.8 Ma. Then, a progressive change from arid-semiarid towards hyperarid conditions and predominantly hyperarid conditions may have persisted since at least ca. 3.3 Ma. The climatic implications inferred from the weathering geochronology are in agreement with the chemical parameters and isotopic compositions of the Cenozoic sedimentary sequence from the Lianmuqin section in the Tu-Ha Basin, attesting to the reliability of weathering geochronology by the 40Ar/39Ar method as an indicator of paleoclimate in arid areas. Our results suggest that the retreat of the Paratethys Sea, which would have reduced eastward water vapor transport by the westerlies to the Tu-Ha Basin, led to its aridification in the Oligocene and that increased rain shadow effects, resulting from uplift of the Tibetan Plateau and Tian Shan

  16. Transgenic Brassica rapa plants over-expressing eIF(iso)4E variants show broad-spectrum Turnip mosaic virus (TuMV) resistance.

    Science.gov (United States)

    Kim, Jinhee; Kang, Won-Hee; Hwang, Jeena; Yang, Hee-Bum; Dosun, Kim; Oh, Chang-Sik; Kang, Byoung-Cheorl

    2014-08-01

    The protein-protein interaction between VPg (viral protein genome-linked) of potyviruses and eIF4E (eukaryotic initiation factor 4E) or eIF(iso)4E of their host plants is a critical step in determining viral virulence. In this study, we evaluated the approach of engineering broad-spectrum resistance in Chinese cabbage (Brassica rapa) to Turnip mosaic virus (TuMV), which is one of the most important potyviruses, by a systematic knowledge-based approach to interrupt the interaction between TuMV VPg and B. rapa eIF(iso)4E. The seven amino acids in the cap-binding pocket of eIF(iso)4E were selected on the basis of other previous results and comparison of protein models of cap-binding pockets, and mutated. Yeast two-hybrid assay and co-immunoprecipitation analysis demonstrated that W95L, K150L and W95L/K150E amino acid mutations of B. rapa eIF(iso)4E interrupted its interaction with TuMV VPg. All eIF(iso)4E mutants were able to complement an eIF4E-knockout yeast strain, indicating that the mutated eIF(iso)4E proteins retained their function as a translational initiation factor. To determine whether these mutations could confer resistance, eIF(iso)4E W95L, W95L/K150E and eIF(iso)4E wild-type were over-expressed in a susceptible Chinese cabbage cultivar. Evaluation of the TuMV resistance of T1 and T2 transformants demonstrated that the over-expression of the eIF(iso)4E mutant forms can confer resistance to multiple TuMV strains. These data demonstrate the utility of knowledge-based approaches for the engineering of broad-spectrum resistance in Chinese cabbage. © 2014 BSPP AND JOHN WILEY & SONS LTD.

  17. I Passiuna tu Christù - Rito e teatro di una cantica popolare della Grecìa Salentina

    Directory of Open Access Journals (Sweden)

    Diana Costa

    2012-01-01

    Full Text Available Abstract – IT Questo articolo si basa sugli esiti di una ricerca di campo condotta nei paesi della Grecìa Salentina,una zona del basso Salento, dove si riscontra una peculiare modalità di esecuzione della cantica popolare grìca conosciuta come I Passiuna tu Christù (La Passione di Cristo. Attorno alla metà degli anni ´90 del ´900 la tradizione della cantica è stata oggetto di un prezioso recupero, fondato sulla memoria e disponibilità di alcuni anziani cantori, che l’ha riportata in vita dopo anni di silenzio. Lo studio si è quindi focalizzato sull'esecuzione di Zollino, uno dei comuni grecanico-salentini, dove opera l'associazione culturale "Bottega del Teatro" che per prima ha promosso il recupero di cui si è detto. Protagonista e interprete raffinato della versione zollinese è l'anziano cantore Antimo Pellegrino, la cui voce si fa teatro attraverso un uso sapiente del corpo fatto di gesti stilizzati, regolati da codici che consentono di comprendere il divenire performativo, ossia il testo in grìco, anche a chi non intende tale idioma. Abstract – EN This article is based on the results of a field research conducted in the countries of the Grecìa Salentina, an area of Salento, where there is a particular execution method of the folksong known as I Passiuna tu Christù (The Passion of the Christ. Around the mid-90s of the 20th century the tradition of this folksong has been the subject of a careful recovery, based on memory and availability of some older singers, who brought it back to life after years of silence. The study then focused on the Zollino’s execution, one of the grecanico-salentino’s common, in which works the cultural association "Bottega del Teatro", the first promoter of this recovery. The old singer Antimo Pellegrino is the player and interpreter of the Zollino’s refined version, whose voice becomes theater through a wise use of body made of stylized gestures, regulated by codes that allow you to

  18. Increasing HIV-related knowledge, communication, and testing intentions among Latinos: Protege tu Familia: Hazte la Prueba.

    Science.gov (United States)

    Rios-Ellis, Britt; Espinoza, Lilia; Bird, Mara; Garcia, Melawhy; D'Anna, Laura Hoyt; Bellamy, Laura; Scolari, Rosana

    2010-08-01

    Latinos are less likely to be aware of their HIV seropositivity than African Americans and Whites. 'Protege tu Familia: Hazte la Prueba' is a culturally and linguistically-sensitive HIV/AIDS prevention and testing program targeting Latino families. Using community-based participatory research techniques, Spanish-speaking bicultural community health workers helped develop and then used an educational flip chart and materials to conduct outreach and HIV prevention education in diverse settings. The intervention was created to increase HIV/AIDS-related knowledge, to improve communication regarding sexual risk, and to augment intentions to use condoms and test for HIV. A secondary purpose was to decrease HIV-related stigma by improving knowledge about transmission and reducing homophobia. Participants demonstrated significant increases in HIV knowledge, intention to practice safer sex and communicate sexual risk to partner(s), and intention to test for HIV. Improvements were also found in self-reported comfort levels when interacting with and caring for the HIV positive, thus decreasing HIV/AIDS-related stigma.

  19. Applications of GPR in archaeological prospecting and cultural heritage diagnostics: Research Perspectives in COST Action TU1208

    Science.gov (United States)

    Pajewski, Lara; Benedetto, Andrea; Schettini, Giuseppe; Soldovieri, Francesco

    2013-04-01

    Ground Penetrating Radar (GPR) is a safe, non-destructive and non-invasive imaging technique that can be effectively used for advanced inspection of composite structures and for diagnostics affecting the whole life-cycle of civil engineering works. GPR can also be successfully employed in archaeological prospecting and cultural heritage diagnostics. In many Countries, where the archeological patrimony is an outstanding value (as Egypt, Israel, Greece, Central and South America), GPR is usually employed both as a diagnostic tool for the preventive detection of archeological structures and as the most advanced instrument able to prospect geometry and shape of underground valuable sites. However many uncertainties persist, because of several difficulties and ambiguities due to the complexity of the image processing in heterogeneous environment. It is possible to identify three main areas, in GPR field, that have to be addressed in order to promote the use of this technology in archaeological prospecting and cultural heritage diagnostics. These are: a) increase of the system sensitivity to enable the usability in a wider range of conditions, archeological sites are often located in impervious and critical environments; b) research novel data processing algorithms/analysis tools for the interpretation of GPR results; c) contribute to the development of new standards and guidelines and to training of end users, that will also help to increase the awareness of operators. It is also important to further investigate and promote a combined use of GPR with other non-invasive advanced techniques, typically used in the archeological investigation. In this framework, the COST Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar", proposed by a research team of "Roma Tre" University, Rome, Italy, has been approved in November 2012 and is going to start in April 2013. It is a 4-years ambitious project already involving 17 European Countries (AT, BE, CH, CZ, DE

  20. Control de criaderos de Aedes aegypti con el programa Recicla por tu bienestar en Mérida, México

    Directory of Open Access Journals (Sweden)

    Mario Barrera Pérez

    2015-05-01

    Full Text Available Objetivos. Determinar la importancia de los criaderos de Ae. aegypti en Mérida; evaluar el impacto del programa Recicla or tu bienestar (RxB sobre la presencia/abundancia de éstos y la percepción de los habitantes. Material y métodos. Se calculó la importancia de los criaderos por su productividad pupal. Se realizaron muestreos pre y post RxB en colonias para cuantificar el total de recipientes/criaderos. Se aplicó una encuesta a participantes sobre la percepción sobre RxB en colonias seleccionadas. Resultados. Los botes, cubetas y diversos objetos chicos fueron los criaderos más importantes. RxB tuvo un impacto significativo en la reducción del número de recipientes (IRR=0.74, en los recipientes positivos (IRR=0.33 y en la positividad de las viviendas para Ae. aegypti (OR=0.41. Todos los entrevistados opinaron que RxB es necesario la gran mayoría piensa que es útil. Conclusiones. RxB debe ser considerada una buena práctica para el control del vector del dengue.

  1. The nuclear inclusion a (NIa protease of turnip mosaic virus (TuMV cleaves amyloid-β.

    Directory of Open Access Journals (Sweden)

    Hye-Eun Han

    Full Text Available BACKGROUND: The nuclear inclusion a (NIa protease of turnip mosaic virus (TuMV is responsible for the processing of the viral polyprotein into functional proteins. NIa was previously shown to possess a relatively strict substrate specificity with a preference for Val-Xaa-His-Gln↓, with the scissile bond located after Gln. The presence of the same consensus sequence, Val(12-His-His-Gln(15, near the presumptive α-secretase cleavage site of the amyloid-β (Aβ peptide led us to hypothesize that NIa could possess activity against Aβ. METHODOLOGY/PRINCIPAL FINDINGS: Western blotting results showed that oligomeric as well as monomeric forms of Aβ can be degraded by NIa in vitro. The specific cleavage of Aβ was further confirmed by mass spectrometry analysis. NIa was shown to exist predominantly in the cytoplasm as observed by immunofluorescence microscopy. The overexpression of NIa in B103 neuroblastoma cells resulted in a significant reduction in cell death caused by both intracellularly generated and exogenously added Aβ. Moreover, lentiviral-mediated expression of NIa in APP(sw/PS1 transgenic mice significantly reduced the levels of Aβ and plaques in the brain. CONCLUSIONS/SIGNIFICANCE: These results indicate that the degradation of Aβ in the cytoplasm could be a novel strategy to control the levels of Aβ, plaque formation, and the associated cell death.

  2. Small reactor power systems for manned planetary surface bases

    Energy Technology Data Exchange (ETDEWEB)

    Bloomfield, H.S.

    1987-12-01

    A preliminary feasibility study of the potential application of small nuclear reactor space power systems to manned planetary surface base missions was conducted. The purpose of the study was to identify and assess the technology, performance, and safety issues associated with integration of reactor power systems with an evolutionary manned planetary surface exploration scenario. The requirements and characteristics of a variety of human-rated modular reactor power system configurations selected for a range of power levels from 25 kWe to hundreds of kilowatts is described. Trade-off analyses for reactor power systems utilizing both man-made and indigenous shielding materials are provided to examine performance, installation and operational safety feasibility issues. The results of this study have confirmed the preliminary feasibility of a wide variety of small reactor power plant configurations for growth oriented manned planetary surface exploration missions. The capability for power level growth with increasing manned presence, while maintaining safe radiation levels, was favorably assessed for nominal 25 to 100 kWe modular configurations. No feasibility limitations or technical barriers were identified and the use of both distance and indigenous planetary soil material for human rated radiation shielding were shown to be viable and attractive options.

  3. Food concentrations and dietary intakes of elements for Chinese man

    International Nuclear Information System (INIS)

    Zhu Hongda; Wang Jixian; Chen Rusong

    2000-01-01

    Objective: To obtain concentrations of elements in Chinese current foods and their dietary intakes by adult man in order to provide a basis on intake parameters of Chinese Reference Man and make related hygienic evaluation. Methods: With mixed food sample method of total diet study, determination of element concentrations in constituent foods of diets for 4 areas with different diet types was carried out by using NAA, ICP-MS, ICP-AES, AAS and necessary QA measures, and estimation of their daily intakes and hygienic evaluation were also made. Results: The concentrations of 42 elements in 12 categories of foods, their intakes and hygienic evaluation for adult man were obtained. Conclusion: The data on element concentrations in Chinese foods and their dietary intakes were updated and widened. These data provided a new basis for developing the parameters of Chinese Reference Man and revealed some current hygienic problems. For example, from viewpoint of nutrition hygiene the Ca, Zn, and Cu intakes for Chinese Reference Man are insufficient, and from consideration of food hygiene the intakes of Pb,Cd and Na are excessive.. Especially, and Cd average daily intakes of Pb, Cd and Hg have been increased during recent years, those of Pb exceed their ADIs, which should be paid attention to

  4. Effect of Variable Manning Coefficients on Tsunami Inundation

    Science.gov (United States)

    Barberopoulou, A.; Rees, D.

    2017-12-01

    Numerical simulations are commonly used to help estimate tsunami hazard, improve evacuation plans, issue or cancel tsunami warnings, inform forecasting and hazard assessments and have therefore become an integral part of hazard mitigation among the tsunami community. Many numerical codes exist for simulating tsunamis, most of which have undergone extensive benchmarking and testing. Tsunami hazard or risk assessments employ these codes following a deterministic or probabilistic approach. Depending on the scope these studies may or may not consider uncertainty in the numerical simulations, the effects of tides, variable friction or estimate financial losses, none of which are necessarily trivial. Distributed manning coefficients, the roughness coefficients used in hydraulic modeling, are commonly used in simulating both riverine and pluvial flood events however, their use in tsunami hazard assessments is primarily part of limited scope studies and for the most part, not a standard practice. For this work, we investigate variations in manning coefficients and their effects on tsunami inundation extent, pattern and financial loss. To assign manning coefficients we use land use maps that come from the New Zealand Land Cover Database (LCDB) and more recent data from the Ministry of the Environment. More than 40 classes covering different types of land use are combined into major classes such as cropland, grassland and wetland representing common types of land use in New Zealand, each of which is assigned a unique manning coefficient. By utilizing different data sources for variable manning coefficients, we examine the impact of data sources and classification methodology on the accuracy of model outputs.

  5. Small reactor power systems for manned planetary surface bases

    International Nuclear Information System (INIS)

    Bloomfield, H.S.

    1987-12-01

    A preliminary feasibility study of the potential application of small nuclear reactor space power systems to manned planetary surface base missions was conducted. The purpose of the study was to identify and assess the technology, performance, and safety issues associated with integration of reactor power systems with an evolutionary manned planetary surface exploration scenario. The requirements and characteristics of a variety of human-rated modular reactor power system configurations selected for a range of power levels from 25 kWe to hundreds of kilowatts is described. Trade-off analyses for reactor power systems utilizing both man-made and indigenous shielding materials are provided to examine performance, installation and operational safety feasibility issues. The results of this study have confirmed the preliminary feasibility of a wide variety of small reactor power plant configurations for growth oriented manned planetary surface exploration missions. The capability for power level growth with increasing manned presence, while maintaining safe radiation levels, was favorably assessed for nominal 25 to 100 kWe modular configurations. No feasibility limitations or technical barriers were identified and the use of both distance and indigenous planetary soil material for human rated radiation shielding were shown to be viable and attractive options

  6. TU-E-BRD-01: President’s Symposium: The Necessity of Innovation in Medical Physics

    International Nuclear Information System (INIS)

    Bayouth, J; Siewerdsen, J; Wahl, E

    2014-01-01

    This abstract will not blow you away, but speed-painting presenter Erik Wahl will certainly make a truly unique AAPM symposium that you will not want to miss. Along with clinical director John Bayouth and scientific leader Jeff Siewerdsen, this session will highlight innovation. To avoid being button pushers and irrelevant investigators of yesterday’s science, we must innovate. This is particularly challenging in the changing landscape of declining research funding and healthcare reimbursement. But all hope is not lost, Medical Physics is a field born out of innovation. As scientists we quickly translated the man-made and natural phenomena of radiation into a tool that could diagnose broken bones, locate foreign objects imbedded within the body, and treat a spectrum of diseases. As hyperbolae surrounding the curative powers of radiation overcame society, physicists continued their systematic pursuit of a fundamental understanding of radiation and applied their knowledge to enable the diagnostic and therapeutic power of this new tool. Health economics and the decline in research funding have put the Medical Physicist in a precarious position: how do we optimally participate in medical research and advanced patient care in the face of many competing needs? Today's diagnostic imaging and therapeutic approaches are tremendously sophisticated. Researchers and commercial vendors are producing technologies at a remarkable rate; to enable their safe and effective implementation Medical Physicists must work from a fundamental understanding of these technologies. This requires all of us, clinically practicing Medical Physicists, Researchers and Educators alike, to combine our training in scientific methods with innovation. Innovation is the key to our past, a necessity for our contemporary challenges, and critical for the future of Medical Physics. The keynote speakers for the 2014 AAPM Presidential Symposium session will address the way we approach these vitally

  7. TU-E-BRD-01: President’s Symposium: The Necessity of Innovation in Medical Physics

    Energy Technology Data Exchange (ETDEWEB)

    Bayouth, J [University of Wisconsin, Madison, WI (United States); Siewerdsen, J [Johns Hopkins University, Baltimore, MD (United States); Wahl, E [Premiere Speakers Bureau, Franklin, TN (United States)

    2014-06-15

    This abstract will not blow you away, but speed-painting presenter Erik Wahl will certainly make a truly unique AAPM symposium that you will not want to miss. Along with clinical director John Bayouth and scientific leader Jeff Siewerdsen, this session will highlight innovation. To avoid being button pushers and irrelevant investigators of yesterday’s science, we must innovate. This is particularly challenging in the changing landscape of declining research funding and healthcare reimbursement. But all hope is not lost, Medical Physics is a field born out of innovation. As scientists we quickly translated the man-made and natural phenomena of radiation into a tool that could diagnose broken bones, locate foreign objects imbedded within the body, and treat a spectrum of diseases. As hyperbolae surrounding the curative powers of radiation overcame society, physicists continued their systematic pursuit of a fundamental understanding of radiation and applied their knowledge to enable the diagnostic and therapeutic power of this new tool. Health economics and the decline in research funding have put the Medical Physicist in a precarious position: how do we optimally participate in medical research and advanced patient care in the face of many competing needs? Today's diagnostic imaging and therapeutic approaches are tremendously sophisticated. Researchers and commercial vendors are producing technologies at a remarkable rate; to enable their safe and effective implementation Medical Physicists must work from a fundamental understanding of these technologies. This requires all of us, clinically practicing Medical Physicists, Researchers and Educators alike, to combine our training in scientific methods with innovation. Innovation is the key to our past, a necessity for our contemporary challenges, and critical for the future of Medical Physics. The keynote speakers for the 2014 AAPM Presidential Symposium session will address the way we approach these vitally

  8. 77 FR 20882 - Manning Grain Company; Acquisition and Operation Exemption; Fillmore Western Railway Company

    Science.gov (United States)

    2012-04-06

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35612] Manning Grain Company; Acquisition and Operation Exemption; Fillmore Western Railway Company Manning Grain Company (MGC... Docket No. FD 35607, Manning Rail, Inc.--Acquisition and Operation Exemption--Manning Grain Company...

  9. Igbo man's Belief in Prayer for the Betterment of Life | Okodo ...

    African Journals Online (AJOL)

    The Igbo man believes in Chukwu strongly. The Igbo man expects all he needs for the betterment of his life from Chukwu. He worships Chukwu traditionally. His religion, the African Traditional Religion, was existing before the white man came to the Igbo land of Nigeria with his Christianity. The Igbo man believes that he ...

  10. Evaluation of the airway of the SimMan full-scale patient simulator

    DEFF Research Database (Denmark)

    Hesselfeldt, R; Kristensen, M S; Rasmussen, L S

    2005-01-01

    SimMan is a full-scale patient simulator, capable of simulating normal and pathological airways. The performance of SimMan has never been critically evaluated.......SimMan is a full-scale patient simulator, capable of simulating normal and pathological airways. The performance of SimMan has never been critically evaluated....

  11. Propulsive options for a manned Mars transportation system

    International Nuclear Information System (INIS)

    Braun, R.D.; Blersch, D.J.

    1989-01-01

    In this investigation, five potential manned Mars transportation systems are compared. These options include: (1) a single vehicle, chemically propelled (CHEM) option, (2) a single vehicle, nuclear thermal propulsion (NTP) option, (3) a single vehicle solar electric propulsion (SEP) option, (4) a single vehicle hybrid nuclear electric propulsion (NEP)/CHEM option, and (5) a dual vehicle option (NEP cargo spacecraft and CHEM manned vehicle). In addition to utilizing the initial vehicle weight in low-earth orbit as a measure of mission feasibility, this study addresses the major technological barriers each propulsive scenario must surpass. It is shown that instead of a single clearly superior propulsion system, each means of propulsion may be favored depending upon the specified program policy and the extent of the desired manned flight time. Furthermore, the effect which aerobraking and multiple transfer cycles have upon mission feasibility is considered. 18 refs

  12. Manned underwater intervention during deep-water operations

    Energy Technology Data Exchange (ETDEWEB)

    Lothe, Mikal Sjur

    2010-07-01

    The focus for deep and remote areas operations are Remote Operated systems. Manned intervention is generally first choice when looking for intervention methods in most areas of the world. As an industry we need to focus on the most cost effective and safe method for construction, Maintenance and Repair. The focus is on advances in diving methods related to surface oriented and saturation diving, such as shallow water tie-ins of risers and umbilicals, inspection and evaluations of FPSOs including thruster change-out and wet docking. Also, the options for efficient repair scenarios utilizing man's ability to work in low visibility areas by feel etc. Finally the presentation will show new technology in Saturation Diving based on the 24 man saturation systems onboard the 3rd generation Divex systems used by Technip and Subsea 7. (Author)

  13. The strangest man. The hidden life of Paul Dirac

    International Nuclear Information System (INIS)

    Farmelo, Graham

    2016-01-01

    The Strangest Man is the Costa Biography Award-winning account of Paul Dirac, the famous physicist sometimes called the British Einstein. He was one of the leading pioneers of the greatest revolution in twentieth-century science: quantum mechanics. The youngest theoretician ever to win the Nobel Prize for Physics, he was also pathologically reticent, strangely literal-minded and legendarily unable to communicate or empathize. Through his greatest period of productivity, his postcards home contained only remarks about the weather. Based on a previously undiscovered archive of family papers, Graham Farmelo celebrates Dirac's massive scientific achievement while drawing a compassionate portrait of his life and work. Farmelo shows a man who, while hopelessly socially inept, could manage to love and sustain close friendship. The Strangest Man is an extraordinary and moving human story, as well as a study of one of the most exciting times in scientific history.

  14. The CANDU man-machine interface and simulator training

    International Nuclear Information System (INIS)

    Hinchley, E.M.; Yanofsky, N.

    1982-09-01

    The most significant features of the man-machine interface for CANDU power stations are the extensive use of computer-driven colour graphics displays and the small number of manual controls. The man-machine interface in CANDU stations is designed to present the operator with concise, easy-to-understand information. Future developments in the use of computers in safety shutdown systems, and the use of data highway technologies in plant regulating systems will present special requirements and new opportunities in the application of human factors engineering to the control room. Good man-machine interaction depends on operator training as much as on control room design. In Canada computerized training simulators, which indicate plant response to operator action, are being introducted for operator training. Such simulators support training in normal operation of all plant systems and also in the fault management tasks following malfunctions

  15. Multimedia Discovery of the Leonardo’s Vitruvian Man

    Directory of Open Access Journals (Sweden)

    Eva Savina Maliverni

    2015-07-01

    Full Text Available The dissemination and exploitation of cultural heritage milestones by using multimedia and interactive technologies continuously and quickly grows capturing the attention of academia and companies. It is necessary to adopt the state of the art technologies to present and make bi-directional the interaction of users with cultural heritage objects. In this work, we present two different applications of novel technologies applied to the Vitruvian man of Leonardo. The first application is the mirror that exploits a 3D depth sensor to compare the proportions of a user with the perfect ones of the Vitruvian man. The second application is a complex interaction between a complete novel 3D model of the Leonardo’s Vitruvian Man, sounds and image effects inside a 360-degrees hologram. These two systems are the results of interaction between academia and the 3D EVE spin-off company.

  16. New dimensions for man. [human functions in future space missions

    Science.gov (United States)

    Louviere, A. J.

    1978-01-01

    The functions of man in space have been in a state of constant change since the first manned orbital flight. Initially, the onboard crewmen performed those tasks essential to piloting and navigating the spacecraft. The time devoted to these tasks has steadily decreased and the crewman's time is being allotted to functions other than orbital operations. The evolving functions include added orbital operational capabilities, experimentation, spacecraft maintenance, and fabrication of useful end items. The new functions will include routine utilization of the crewman to extend mission life, satellite retrieval and servicing, remote manipulator systems operations, and piloting of free-flying teleoperator systems. The most demanding tasks are anticipated to be associated with construction of large space structures. The projected changes will introduce innovative designs and revitalize the concepts for utilizing man in space.

  17. Heidegger: Sense-Nonsense Dualism of Man in Technology Dimensions

    Directory of Open Access Journals (Sweden)

    Nathalia Andrea Álvarez

    2008-12-01

    Full Text Available This article tries to analyze the ontological-existential compromise that man acquires when using new technologies, in the light of theHeideggerian’ proposal. This compromise means, on the one hand, theresponsibility of forgetting the self in technology, which immerses man in a non-sense; and on the other, the will to open himself to the recognition of the ways in which his “being-in-the-world” manifests. To this end, the perils of technological “instrumentalization” will be presented, based upon the Heideggerian explanation about the essence of technology. We will present the Heideggerian concepts of anxiety1 and nothingness concepts, with which we will try to conduct the postmodern man towards the encounter with his original sense.

  18. Immunohistochemical localization of epidermal growth factor in rat and man

    DEFF Research Database (Denmark)

    Poulsen, Steen Seier; Nexø, Ebba

    1986-01-01

    Epidermal growth factor (EGF) is a peptide which stimulates cell mitotic activity and differentiation, has a cytoprotective effect on the gastroduodenal mucosa, and inhibits gastric acid secretion. The immunohistochemical localization of EGF in the Brunner's glands and the submandibular glands is...... antisera against human urinary EGF worked in rat as well as man. EGF was found only in cells with an exocrine function.......Epidermal growth factor (EGF) is a peptide which stimulates cell mitotic activity and differentiation, has a cytoprotective effect on the gastroduodenal mucosa, and inhibits gastric acid secretion. The immunohistochemical localization of EGF in the Brunner's glands and the submandibular glands...... is well documented. The localization of EGF in other tissues is still unclarified. In the present study, the immunohistochemical localization of EGF in tissues from rat, man and a 20 week human fetus were investigated. In man and rat, immunoreaction was found in the submandibular glands, the serous glands...

  19. Reference Man for Asians as well as for Europeans-A change in the ICRP concept of Reference Man

    International Nuclear Information System (INIS)

    Tanaka, Gi-ichiro

    1990-01-01

    ICRP Reference Man, according to the definition, is primarily for Caucasoid populations (Western Europeans and North Americans) that contribute only 13 per cent of the world population. A speculative world population dose will, assuming a uniform exposure all over the world at a level of 10 μSv, be 50 k man Sv in total. Of this, all regions of Caucasoid populations may contribute by 22 per cent maximum. Asian populations will share about 58 per cent (29 k man Sv) of the world population dose. About eighty per cents in total of the world population can be convered by scientific dose assessment, if Reference Man data for Asians are made available. Thus the importance of establishing Asian Reference Man should be evident. The important point of characteristics of Asians is that they are 'Vegetarians' as compared to Westerners, which suggests different pathways with respect to transfer of radionuclides from foods to the human body. Therefore it is required to determine accurate and suitable parameters relevant to dose assessment. Considering the above, contribution of Japan in science and technology to Asian countries with 'knowhows' accumulated may be of a most urgent matter. (author)

  20. Mechanical Properties of Man-Made Mineral glass fibres

    DEFF Research Database (Denmark)

    Lund, Majbritt Deichgræber; Yue, Yuanzheng

    of man made mineral wool fibres, and an improvement of the mechanical performances of man made mineral wool fibres are an evitable task for us. To do so, it is important to look into the fracture behaviour and its connection to the mechanical strength. In order to improve the understanding...... of the information gained from the mechanical tests, fracture characteristics of individual glass fibres are imaged by scanning electron microscopy. The fracture surfaces showed to fall in three groups; 1) surfaces including fracture mirror, mist and hackle, 2) bend fracture surfaces and 3) surfaces including pores...

  1. Radiocarbon dates to access the origin of the ice man

    Energy Technology Data Exchange (ETDEWEB)

    Niklaus, R. [Institute of Particle Physics, ETH Zurich, Hongerberg (Switzerland)]|[Commonwealth Scientific and Industrial Research Organisation (CSIRO), North Ryde, NSW (Australia). Div. of Exploration Geoscience; Bonani, G. [Institute of Particle Physics, ETH Zurich, Hongerberg (Switzerland); Prinoth-Fornwagner, R. [Innsbruck Univ. (Austria)

    1996-12-31

    Different samples from the Late and Final Neolithic in Northern Italy were radiocarbon dated at the AMS Facility in Zurich, Switzerland in order to determine the origin of the Ice Man from the Hauslabjoch. The cultural classification was obtained on the basis of topological studies of the cooper axe and of the flint dagger as well as studies of artefact materials (the flint or the wood of a composite arrow), while the chronological classification of the Ice Man was obtained with the help of new and old radiocarbon dates. 9 refs., 1 tab., 2 figs.

  2. Proposed man-rem reference values of occupational exposure

    International Nuclear Information System (INIS)

    Lombard, J.

    1988-04-01

    This report presents a proposal of referent collective dose (man-rem) values for occupational exposure related to operation of French pressurized water reactors. These values, permitting adequate choice of protection both at design and operation level, are dependent on the level of annual individual doses. The man-rem value, originating from annual individual doses less than 0.5 rem are estimated to 1 kf. The proposed value is 20 kf for annual individual exposures between 0.5 and 3 rem, and 90 kf for annual individual exposures between 3 and 5 rem. (author) [fr

  3. FROM PONDS TO MAN-MADE SEAS IN RUSSIA

    Directory of Open Access Journals (Sweden)

    Sergey Gorshkov

    2013-01-01

    Full Text Available Russia has more than 2200 reservoirs and large ponds. As time went by, ponds lost their importance in some aspects of human life, while newly created man-made seas impacted the nature and the people in two ways. The costs involved in designing, constructing, and operating the artificial seas, especially on the plains, have been too high to consider them as an undisputed achievement of the Soviet scientists transforming the nature. This paper discusses the problem of ponds and man-made seas in Russia.

  4. Radiocarbon dates to access the origin of the ice man

    Energy Technology Data Exchange (ETDEWEB)

    Niklaus, R [Institute of Particle Physics, ETH Zurich, Hongerberg (Switzerland); [Commonwealth Scientific and Industrial Research Organisation (CSIRO), North Ryde, NSW (Australia). Div. of Exploration Geoscience; Bonani, G [Institute of Particle Physics, ETH Zurich, Hongerberg (Switzerland); Prinoth-Fornwagner, R [Innsbruck Univ. (Austria)

    1997-12-31

    Different samples from the Late and Final Neolithic in Northern Italy were radiocarbon dated at the AMS Facility in Zurich, Switzerland in order to determine the origin of the Ice Man from the Hauslabjoch. The cultural classification was obtained on the basis of topological studies of the cooper axe and of the flint dagger as well as studies of artefact materials (the flint or the wood of a composite arrow), while the chronological classification of the Ice Man was obtained with the help of new and old radiocarbon dates. 9 refs., 1 tab., 2 figs.

  5. Low cost manned Mars mission based on indigenous propellant production

    Science.gov (United States)

    Bruckner, A. P.; Cinnamon, M.; Hamling, S.; Mahn, K.; Phillips, J.; Westmark, V.

    1993-01-01

    The paper describes a low-cost approach to the manned exploration of Mars (which involves an unmanned mission followed two years later by a manned mission) based on near-term technologies and in situ propellant production. Particular attention is given to the basic mission architecture and its major components, including the orbital analysis, the unmanned segment, the Earth Return Vehicle, the aerobrake design, life sciences, guidance, communications, power, propellant production, the surface rovers, and Mars science. Also discussed are the cost per mission over an assumed 8-yr initiative.

  6. Man-machine cooperation in remote handling for fusion plants

    International Nuclear Information System (INIS)

    Leinemann, K.

    1984-01-01

    Man-machine cooperation in remote handling for fusion plants comprises cooperation for design of equipment and planning of procedures using a CAD system, and cooperation during operation of the equipment with computer aided telemanipulation systems (CAT). This concept is presently being implemented for support of slave positioning, camera tracking, and camera alignment in the KfK manipulator test facility. The pilot implementation will be used to test various man-machine interface layouts, and to establish a set of basic buildings blocks for future implementations of advanced remote handling control systems. (author)

  7. Review on abort trajectory for manned lunar landing mission

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Abort trajectory is a passage that ensures the astronauts to return safely to the earth when an emergency occurs. Firstly,the essential elements of mission abort are analyzed entirely based on summarizing the existing studies. Then,abort trajectory requirement and rational selection for different flight phases of typical manned lunar mission are discussed specifically. Considering a trade-off between the two primary constrains of an abort,the return time of flight and energy requirement,a general optimizing method for mission abort is proposed. Finally,some suggestions are given for China’s future manned lunar landing mission.

  8. Influence map baserad Ms. Pac-Man och Ghost Kontroller

    OpenAIRE

    Svensson, Johan

    2012-01-01

    This thesis will cover the use oftheinfluence map technique applied to the retro game Ms. Pac-Man. A game thatis easy to learn but hard to master. The Ms. Pac-Man controller is implemented with five main parameters that alters the behaviour of the controller while the Ghost controller have three parameters. The experimental results of the controllers is explored to using the alterations of the parameters to find its peak of performance. The conclusion from using the influence map for this gam...

  9. Fragmented one dimensional man / El hombre unidimensional fragmentado

    Directory of Open Access Journals (Sweden)

    Juan Antonio Rodríguez del Pino

    2013-10-01

    Full Text Available Paraphrase the title of the famous essay by Herbert Marcuse, since the image has traditionally been generated of man, masculinity, has been one-dimensional. I mean, the man was characterized by traits and behaviors established and entrenched since ancient time, considering all other distinguishing signs as mere deviations from the normative improper. But observe that this undeniable reality, as analyzed various researchers through what has come to be called Men's studies, has proven to be a fallacy difficult to maintain throughout history and today turns into fallacious and ineffective against changes in our current existing corporate models.

  10. The evolution of automation and robotics in manned spaceflight

    Science.gov (United States)

    Moser, T. L.; Erickson, J. D.

    1986-01-01

    The evolution of automation on all manned spacecraft including the Space Shuttle is reviewed, and a concept for increasing automation and robotics from the current Shuttle Remote Manipulator System (RMS) to an autonomous system is presented. The requirements for robotic elements are identified for various functions on the Space Station, including extravehicular functions and functions within laboratory and habitation modules which expand man's capacity in space and allow selected teleoperation from the ground. The initial Space Station will employ a telerobot and necessary knowledge based systems as an advisory to the crew on monitoring, fault diagnosis, and short term planning and scheduling.

  11. Data base on avian mortality on man-made structures

    Energy Technology Data Exchange (ETDEWEB)

    Dailey, N. S.

    1978-01-01

    A computerized data base concerning avian mortality on man-made structures is available for searching at the Ecological Sciences Information Center of the Information Center Complex, Information Division, Oak Ridge National Laboratory. This data base, which contains entries from the available literature, provides information on avian mortality from either collision into or electrocution on man-made structures. Primary emphasis has been placed on avian collision with obstacles such as television and radio towers, airport ceilometers, transmission lines, and cooling towers. Other structures included in the studies are fences, glass walls and windows, lighthouses, telegraph and telephone wires, buildings, monuments, smokestacks, and water towers.

  12. Heidegger: Sense-Nonsense Dualism of Man in Technology Dimensions

    OpenAIRE

    Nathalia Andrea Álvarez

    2008-01-01

    This article tries to analyze the ontological-existential compromise that man acquires when using new technologies, in the light of theHeideggerian’ proposal. This compromise means, on the one hand, theresponsibility of forgetting the self in technology, which immerses man in a non-sense; and on the other, the will to open himself to the recognition of the ways in which his “being-in-the-world” manifests. To this end, the perils of technological “instrumentalization” will be presented, based ...

  13. 'Manxness': The Uses of Heritage on the Isle of Man

    Directory of Open Access Journals (Sweden)

    Elizabeth Catte

    2015-12-01

    Full Text Available This article examines how the Isle of Man, a self-governing crown dependency located in the center of the British Isles, uses heritage to create social stability among a diverse and rapidly changing population. The result of this process has been a powerful model of heritage branding through which all definitions of national identity must flow. After tracing the development of ‘Manx’ national identity from the Victorian era to the present, this article explores the benefits and limitations of the Isle of Man’s political uses of its history and shares insight from the practice of public history on the Isle of Man.

  14. A case of anorexia nervosa in an elderly man.

    Science.gov (United States)

    Malik, Fahd; Wijayatunga, Uditha; Bruxner, George M

    2014-06-01

    To explore aspects of anorexia nervosa occurring in older populations, especially men, by reviewing the literature and presenting a case study of an elderly man with unexplained vomiting and weight loss. The literature is reviewed and an illustrative case study of an elderly man with unexplained vomiting and weight loss is described. Anorexia nervosa is an uncommon cause of unexplained weight loss in the elderly, but may be under-recognized and associated with a high level of mortality. © The Royal Australian and New Zealand College of Psychiatrists 2014.

  15. TU-86. [Denmark]. TU-86; Trafikundersoegelse

    Energy Technology Data Exchange (ETDEWEB)

    1987-03-15

    An investigation of traffic conditions in Denmark limited to ownership of bicycles, autocycles and motorbikes, and to access to, and use of, cars - including car-pooling. The character of road travel in relation to journeys of over 20 km, which are not to and from the place of work, is also examined. (AB).

  16. Effects of carbonated mineral water treatment in Băile Tuşnad on chronic arterial occlusive disease – a case report

    Directory of Open Access Journals (Sweden)

    Gabriela Dogaru

    2017-05-01

    Full Text Available Introduction. Băile Tușnad spa is recognized for its role in the prevention and rehabilitation treatment of cardiovascular diseases, including chronic arterial occlusive disease, due to the presence of natural therapeutic factors: carbonated mineral waters through their peripheral vasodilator effects, natural mofettes, stimulating bioclimate. Aim. The current study aimed to assess the clinical efficiency of natural therapeutic factors in Băile Tuşnad for the continuation of rehabilitation treatment in a patient with chronic arterial occlusive disease, in order to encourage walking, reduce cardiovascular risk and improve quality of life. Material and method. Patient N.M., aged 75, with multiple cardiovascular risk factors. In 2013, he was diagnosed with lower limb peripheral ischemia syndrome stage II B Fontaine, predominantly left claudication at about 100 m, for which balloon angioplasty was performed. He attended rehabilitation treatment for 3 years in Baile Tuşnad, consisting of carbonated mineral water baths for 15 minutes, aerotherapy for 30 minutes daily for the stimulation of walking, massotherapy, kinesiotherapy, performed daily for 16 days, and in 2016, at the Rehabilitation Hospital Cluj-Napoca. He was clinically evaluated before and at the end of treatment by the Visual Analogue Scale, the 10-m walking test, adverse reactions, Doppler ultrasound. Results. At the end of treatment, an increase in the walking distance and speed, a significant improvement in the quality of gait was found; claudication occurred after 250 m, pain in the lower limbs was improved. There were no side reactions. Conclusions. Rehabilitation treatment with natural therapeutic factors influenced the clinical and functional picture, determining a significant improvement in the quality of gait and quality of life.

  17. Elongation Factor Tu Prevents Misediting of Gly-tRNA(Gly Caused by the Design Behind the Chiral Proofreading Site of D-Aminoacyl-tRNA Deacylase.

    Directory of Open Access Journals (Sweden)

    Satya Brata Routh

    2016-05-01

    Full Text Available D-aminoacyl-tRNA deacylase (DTD removes D-amino acids mischarged on tRNAs and is thus implicated in enforcing homochirality in proteins. Previously, we proposed that selective capture of D-aminoacyl-tRNA by DTD's invariant, cross-subunit Gly-cisPro motif forms the mechanistic basis for its enantioselectivity. We now show, using nuclear magnetic resonance (NMR spectroscopy-based binding studies followed by biochemical assays with both bacterial and eukaryotic systems, that DTD effectively misedits Gly-tRNAGly. High-resolution crystal structure reveals that the architecture of DTD's chiral proofreading site is completely porous to achiral glycine. Hence, L-chiral rejection is the only design principle on which DTD functions, unlike other chiral-specific enzymes such as D-amino acid oxidases, which are specific for D-enantiomers. Competition assays with elongation factor thermo unstable (EF-Tu and DTD demonstrate that EF-Tu precludes Gly-tRNAGly misediting at normal cellular concentrations. However, even slightly higher DTD levels overcome this protection conferred by EF-Tu, thus resulting in significant depletion of Gly-tRNAGly. Our in vitro observations are substantiated by cell-based studies in Escherichia coli that show that overexpression of DTD causes cellular toxicity, which is largely rescued upon glycine supplementation. Furthermore, we provide direct evidence that DTD is an RNA-based catalyst, since it uses only the terminal 2'-OH of tRNA for catalysis without the involvement of protein side chains. The study therefore provides a unique paradigm of enzyme action for substrate selection/specificity by DTD, and thus explains the underlying cause of DTD's activity on Gly-tRNAGly. It also gives a molecular and functional basis for the necessity and the observed tight regulation of DTD levels, thereby preventing cellular toxicity due to misediting.

  18. [Classes of crude drugs and its distribution of producing area in the attached illustrations in Ben cao tu jing (Illustrated Classic of Materia Medica)].

    Science.gov (United States)

    Xu, T; Peng, H S

    2016-03-01

    Ben cao tu jing (Illustrated Classic of Materia Medica) is the earliest extant atlas book of materia medica in China, with 933 attached drawings. Among them, the largest portion, amounting to 670, are herbaceous plants, mostly commonly used, with definite marks of the origin producing areas, distributed across 149 administrative divisions(prefectures and counties) of the Song Dynasty, most of them in Northern area which were distributed denser than those in Southern area. The densest ones were located in Southern Shanxi, Eastern Sichuan and Eastern Anhui. In the attached drawings, the frequency of highest occurrence appeared in this Classic are three prefectures, Chuzhou, Shizhou and Guangzhou.

  19. "I Am Chelsea Manning": Comparison of Gendered Representation of Private Manning in U.S. and International News Media.

    Science.gov (United States)

    Hackl, Andrea M; Becker, Amy B; Todd, Maureen E

    2016-01-01

    On August 22, 2013, Bradley Manning released a statement requesting to be referred to as female. In the following days, the news media discussed whether language should shift toward a female representation. Using quantitative content analysis and qualitative contextual analysis, this study analyzed whether U.S. and international newspapers (N = 197) acknowledged Manning's request to be referred to as "Chelsea" in the two weeks after the statement. Results suggest that the mainstream press was hesitant in shifting toward a female representation. A comparison of international and U.S. newspapers suggests that the U.S. press lagged behind international coverage using a female depiction.

  20. Ground-penetrating radar investigation of St. Leonard's Crypt under the Wawel Cathedral (Cracow, Poland) - COST Action TU1208

    Science.gov (United States)

    Benedetto, Andrea; Pajewski, Lara; Dimitriadis, Klisthenis; Avlonitou, Pepi; Konstantakis, Yannis; Musiela, Małgorzata; Mitka, Bartosz; Lambot, Sébastien; Żakowska, Lidia

    2016-04-01

    The Wawel ensemble, including the Royal Castle, the Wawel Cathedral and other monuments, is perched on top of the Wawel hill immediately south of the Cracow Old Town, and is by far the most important collection of buildings in Poland. St. Leonard's Crypt is located under the Wawel Cathedral of St Stanislaus BM and St Wenceslaus M. It was built in the years 1090-1117 and was the western crypt of the pre-existing Romanesque Wawel Cathedral, so-called Hermanowska. Pope John Paul II said his first Mass on the altar of St. Leonard's Crypt on November 2, 1946, one day after his priestly ordination. The interior of the crypt is divided by eight columns into three naves with vaulted ceiling and ended with one apse. The tomb of Bishop Maurus, who died in 1118, is in the middle of the crypt under the floor; an inscription "+ MAVRVS EPC MCXVIII +" indicates the burial place and was made in 1938 after the completion of archaeological works which resulted in the discovery of this tomb. Moreover, the crypt hosts the tombs of six Polish kings and heroes: Michał Korybut Wiśniowiecki (King of the Polish-Lithuanian Commonwealth), Jan III Sobieski (King of the Polish-Lithuanian Commonwealth and Commander at the Battle of Vienna), Maria Kazimiera (Queen of the Polish-Lithuanian Commonwealth and consort to Jan III Sobieski), Józef Poniatowski (Prince of Poland and Marshal of France), Tadeusz Kościuszko (Polish general, revolutionary and a Brigadier General in the American Revolutionary War) and Władysław Sikorski (Prime Minister of the Polish Government in Exile and Commander-in-Chief of the Polish Armed Forces). The adjacent six crypts and corridors host the tombs of the other Polish kings, from Sigismund the Old to Augustus II the Strong, their families and several Polish heroes. In May 2015, the COST (European COoperation in Science and Technology) Action TU1208 "Civil engineering applications of Ground Penetrating Radar" organised and offered a Training School (TS) on the

  1. Exchanging knowledge and working together in COST Action TU1208: Short-Term Scientific Missions on Ground Penetrating Radar

    Science.gov (United States)

    Santos Assuncao, Sonia; De Smedt, Philippe; Giannakis, Iraklis; Matera, Loredana; Pinel, Nicolas; Dimitriadis, Klisthenis; Giannopoulos, Antonios; Sala, Jacopo; Lambot, Sébastien; Trinks, Immo; Marciniak, Marian; Pajewski, Lara

    2015-04-01

    This work aims at presenting the scientific results stemming from six Short-Term Scientific Missions (STSMs) funded by the COST (European COoperation in Science and Technology) Action TU1208 'Civil Engineering Applications of Ground Penetrating Radar' (Action Chair: Lara Pajewski, STSM Manager: Marian Marciniak). STSMs are important means to develop linkages and scientific collaborations between participating institutions involved in a COST Action. Scientists have the possibility to go to an institution abroad, in order to undertake joint research and share techniques/equipment/infrastructures that may not be available in their own institution. STSMs are particularly intended for Early Stage Researchers (ESRs), i.e., young scientists who obtained their PhD since no more than 8 years when they started to be involved in the Action. Duration of a standard STSM can be from 5 to 90 days and the research activities carried out during this short stay shall specifically contribute to the achievement of the scientific objectives of the supporting COST Action. The first STSM was carried out by Lara Pajewski, visiting Antonis Giannopoulos at The University of Edinburgh (United Kingdom). The research activities focused on the electromagnetic modelling of Ground Penetrating Radar (GPR) responses to complex targets. A set of test scenarios was defined, to be used by research groups participating to Working Group 3 of COST Action TU1208, to test and compare different electromagnetic forward- and inverse-scattering methods; these scenarios were modelled by using the well-known finite-difference time-domain simulator GprMax. New Matlab procedures for the processing and visualization of GprMax output data were developed. During the second STSM, Iraklis Giannakis visited Lara Pajewski at Roma Tre University (Italy). The study was concerned with the numerical modelling of horn antennas for GPR. An air-coupled horn antenna was implemented in GprMax and tested in a realistically

  2. Man, Satan, and God of Mawlana (Rumi and Milton

    Directory of Open Access Journals (Sweden)

    Leila Mir Mojarabian

    2013-09-01

    Full Text Available This research is a critical analysis on the place of human and his integration with religious issues, and the subject of disobedience and rebellion. In addition, topics such as reward, punishment, redemption and salvation of mankind in two great works of literature of the world, Masnavi by Mawlana and Paradise Lost by Milton have been comparatively discussed.     Rumi's poetry and thought has been accepted by commons and special people in Iran and the world. Rumi is one of the few supreme poets in Persian language and the world. Generally, Milton has Known as the greatest English poet after Shakespeare, and his Paradise Lost as the greatest English fiction poem. This work is a the well-known epics of human-divine composed in live new languages, and comparing these two works even in one field of speech, indeed is the comparison of two thoughts, two nations, and two ancient cultures.     The author attempts to examine the similarities and contrasts of the two poems of these two great poets on the subjects of human, God, and Satan and the world, to achieve the analytical and critical comparison of them in this context. In this paper the author tries to base the Paradise Lost of Milton and compare it with the ideas of Mawlana common to imagine man's first story and his disobedience, religious approaches, and finally the end presumed for mankind.     In these two poems, contrast between "God" and "man" is derived from the fundamental relationship between "God" and "man". Milton while calls God, our Heavenly Father and refer to his role of creativity, entitles him as the dominant power, All mighty, the victorious winner, Glorious and Holy ruler, powerful king, and in one word, omnipotent. The Creator that all creatures are worshiping him, the omnipotent could be seen his capability remarks in everywhere, the unique structure of the universe beautiful is his own and the glorious ruler, sitting over the skies, sometimes invisible and sometimes

  3. Man, Satan, and God of Mawlana (Rumi and Milton

    Directory of Open Access Journals (Sweden)

    Leila Mir Mojarabian

    Full Text Available This research is a critical analysis on the place of human and his integration with religious issues, and the subject of disobedience and rebellion. In addition, topics such as reward, punishment, redemption and salvation of mankind in two great works of literature of the world, Masnavi by Mawlana and Paradise Lost by Milton have been comparatively discussed. Rumi's poetry and thought has been accepted by commons and special people in Iran and the world. Rumi is one of the few supreme poets in Persian language and the world. Generally, Milton has Known as the greatest English poet after Shakespeare, and his Paradise Lost as the greatest English fiction poem. This work is a the well-known epics of human-divine composed in live new languages, and comparing these two works even in one field of speech, indeed is the comparison of two thoughts, two nations, and two ancient cultures. The author attempts to examine the similarities and contrasts of the two poems of these two great poets on the subjects of human, God, and Satan and the world, to achieve the analytical and critical comparison of them in this context. In this paper the author tries to base the Paradise Lost of Milton and compare it with the ideas of Mawlana common to imagine man's first story and his disobedience, religious approaches, and finally the end presumed for mankind. In these two poems, contrast between "God" and "man" is derived from the fundamental relationship between "God" and "man". Milton while calls God, our Heavenly Father and refer to his role of creativity, entitles him as the dominant power, All mighty, the victorious winner, Glorious and Holy ruler, powerful king, and in one word, omnipotent. The Creator that all creatures are worshiping him, the omnipotent could be seen his capability remarks in everywhere, the unique structure of the universe beautiful is his own and the glorious ruler, sitting over the skies, sometimes invisible and sometimes visible, even

  4. Man, Satan, and God of Mawlana (Rumi and Milton

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Nasre Esfahani

    2013-08-01

    Full Text Available This research is a critical analysis on the place of human and his integration with religious issues, and the subject of disobedience and rebellion. In addition, topics such as reward, punishment, redemption and salvation of mankind in two great works of literature of the world, Masnavi by Mawlana and Paradise Lost by Milton have been comparatively discussed.     Rumi's poetry and thought has been accepted by commons and special people in Iran and the world. Rumi is one of the few supreme poets in Persian language and the world. Generally, Milton has Known as the greatest English poet after Shakespeare, and his Paradise Lost as the greatest English fiction poem. This work is a the well-known epics of human-divine composed in live new languages, and comparing these two works even in one field of speech, indeed is the comparison of two thoughts, two nations, and two ancient cultures.     The author attempts to examine the similarities and contrasts of the two poems of these two great poets on the subjects of human, God, and Satan and the world, to achieve the analytical and critical comparison of them in this context. In this paper the author tries to base the Paradise Lost of Milton and compare it with the ideas of Mawlana common to imagine man's first story and his disobedience, religious approaches, and finally the end presumed for mankind.     In these two poems, contrast between "God" and "man" is derived from the fundamental relationship between "God" and "man". Milton while calls God, our Heavenly Father and refer to his role of creativity, entitles him as the dominant power, All mighty, the victorious winner, Glorious and Holy ruler, powerful king, and in one word, omnipotent. The Creator that all creatures are worshiping him, the omnipotent could be seen his capability remarks in everywhere, the unique structure of the universe beautiful is his own and the glorious ruler, sitting over the skies, sometimes invisible and sometimes

  5. Manned-Unmanned Teaming of Aircraft - Literature Search

    Science.gov (United States)

    2013-12-01

    restricted to 2003 2013. Literature searches were conducted in eight databases Aerospace and High Technology, Scopus , NTIS, Inspec, Compendex, DTIC, Jane’si...Buddy Unmanned wingman Manned-Unmanned Teaming Dec 2013 Page 35 of 37 7.1.2 Sources Online databases • Scopus • Aerospace and High Technology

  6. Case Report: A man on antiretroviral therapy with painful thighs

    African Journals Online (AJOL)

    A 54 year old man presented with increasing pain in both thighs for three months during a follow up visit at the antiretroviral therapy (ART) clinic of Queen Elizabeth. Central Hospital. He was first seen at the same clinic three years and eight months before the current presentation, when he started. ART with ...

  7. Measurements of Man-Made Spectrum Noise Floor

    Science.gov (United States)

    Enge, Per; Akos, Dennis; Do, Juyong; Simoneau, Joel B.; Pearson, L. Wilson; Seetharam, Venkatesh; Oria, A. J. (Editor)

    2004-01-01

    This report consolidates research carried out at Clemson University and Stanford University where a series of measurements were undertaken to identify the man-made radiation present in four bands used by rather different services, namely, L1 Band (1563.42 1587.42 MHz), the Unified S-Band (2025 2110 MHz), the 2.4 GHz Industrial, Scientific and Medical (ISM) Band (2400 2482.50 MHz), and the 23.6-24.0 GHz Passive Sensing Band. Results show that there were distinctive differences in the measurement data in the frequency bands, which should be expected based on the function/regulation associated with each. The GPS L1 Band had little to none terrestrial man-made sources, but the ISM 2.4 GHz Band had a large number of man-made sources regardless of the site and the time. The Unified S Band showed mixed results depending on the sites. The Passive Sensing Band does not contain appreciable man-made radiation.

  8. Ocean Disposal of Man-Made Ice Piers

    Science.gov (United States)

    The National Science Foundation is permitted to ocean dump man-made ice piers from its base at McMurdo Sound in Antarctica under a MPRSA general permit. Information is provided about ice piers and impacts of ice pier disposal.

  9. Are you Wo(man enough to get married?

    Directory of Open Access Journals (Sweden)

    Tiurma M. P. Allagan

    2016-12-01

    Full Text Available Indonesian marriage states that marriage is physical and spiritual relationship between a man and a woman as husband and wife in order to create an eternal happy family based on the Almighty God. This definition reflects that the marriage in Indonesia must be between heterosexual couple. However, a question appears as to whether a man or a woman mentioned thereof is included a man and a woman who were, hermaphrodite, intersex, or nowadays known as person with Disorder of Sexual Development (DSD? The case of AH whereby his marriage is cancelled by the Supreme Court in 2014 for he is not considered as a man, is confirming that this question is important to value the capacity of a person to marry. This writing will apply normative research as well as literature research method upon the positive rules and regulations. The decisions of district courts upon the revision or change of gender and its legal basis will be analysed and be the topic of discussion. Comparison will be applied to compare the marriage requirements between Indonesian Law, Singapore Law and Hong Kong Law. The results of analyse and discussion will be the closure of the writing, as conclusions and advise, if any.

  10. Apraxia of speech in healthy 36-year-old man.

    Science.gov (United States)

    Ramos-Estebanez, Ciro; Gokhale, Sankalp; Goddeau, Richard; Kumar, Sandeep

    2013-08-01

    A 36-year-old healthy man presented with sudden onset speech difficulty. Thorough clinical examination revealed interesting deficits suggestive of apraxia of speech. He was found to have an infarct in his frontal region explaining the deficits. We have undertaken clinical evaluation and differential diagnoses of this condition. Copyright © 2012 Elsevier Ltd. All rights reserved.

  11. LCA single score analysis of man-made cellulose fibres

    NARCIS (Netherlands)

    Shen, L.; Patel, M.K.

    2010-01-01

    In this study, the LCA report “Life Cycle assessment of man-made cellulose fibres” [3] is extended to the single score analysis in order to provide an additional basis for decision making. The single score analysis covers 9 to 11 environmental impact categories. Three single score methods (Single

  12. Herman Charles Bosman: A Man of Profound Contradictions | Leff ...

    African Journals Online (AJOL)

    Herman Charles Bosman is best known for his humorous short stories with signature twist endings. He is less well known for his essays and journalistic writing, which illustrate another side of this enigmatic man. This essay focuses on the paradox that Bosman was (and continues to be) and aims to respond to the following ...

  13. Symmetry in the World of Man and Nature

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 6; Issue 5. Symmetry in the World of Man and Nature - Classification of Isometries. Shailesh A Shirali. General Article Volume 6 Issue 5 May 2001 pp 29-38. Fulltext. Click here to view fulltext PDF. Permanent link:

  14. Ionizing radiation causing a risk of cancer in man

    International Nuclear Information System (INIS)

    Fichardt, T.; Sandison, A.G.; Savage, D.J.

    1977-01-01

    An attempt has been made to present, in short review, the most important carcinogens that have been implicated in the development of cancer in the various organ sites of the human body and to demonstrate the relatively minor role played by ionizing radiation, especially radiotherapy, in causing a risk of cancer in man

  15. Vaccination against acute respiratory virus infections and measles in man.

    NARCIS (Netherlands)

    A.D.M.E. Osterhaus (Albert); P. de Vries (Petra)

    1992-01-01

    textabstractSeveral viruses may cause more or less severe acute respiratory infections in man, some of which are followed by systemic infection. Only for influenza and measles are licensed vaccines available at present. The protection induced by influenza vaccines, which are based on inactivated

  16. Not normally manned compression platforms for the North Sea

    International Nuclear Information System (INIS)

    Kumaran, K.S.

    1994-01-01

    Gas turbine driven gas compressors have been widely used on manned offshore facilities. Similarly unmanned gas turbine driven compressor stations have been in operation onshore with major gas transmission companies in Europe, North America and elsewhere. This paper summarizes a recent joint industry study to investigate the technical and economic feasibility of Not Normally Manned (NNM) Offshore Compression Facilities in terms of reliability, availability and maintainability. Classification of not normally manned (or unmanned) offshore facilities in the UK North Sea is in accordance with HSE Operations Notice 8. ON8 specifies criteria for offshore visits, visit hours and number of personnel on board for the operation of NNM platforms. This paper describes a typical Southern North Sea gas platform being considered for NNM compressor application. The conclusions from the study was that NNM compression is technically feasible with the facilities being able to provide an availability in excess of 98%. Life cycle costs were of the order of 70% of manned facilities thus significantly improving field development economics

  17. Simultaneous Bilateral Bell's palsy in a Nigerian man | Owolabi ...

    African Journals Online (AJOL)

    Bilateral Bellfs palsy occurring simultaneously is exceedingly rare. We report a case of a 27.year.old Nigerian man with bilateral Bellfs palsy, that occurred simultaneously, who had remarkable response to steroid and physiotherapy. We emphasized the importance of considering Bellfs palsy and the various differential ...

  18. Man and Nature | Elimimian | Lwati: A Journal of Contemporary ...

    African Journals Online (AJOL)

    An important area of Senghor's verse, which has not received any serious critical consideration among critics, centers on Man and Nature. The reason for this critical neglect is hard to fathom, especially, considering the fact that everything we have discussed about Senghor's poetics -- including Negritude, womanhood, the ...

  19. James J. Gallagher: Man in the White Hat

    Science.gov (United States)

    Jolly, Jennifer L.; Robinson, Ann

    2014-01-01

    In classic Western movies, the good guy could be frequently identified by his trademark white Stetson hat, whereas the bad guy always wore black. James J. Gallagher wore many hats during his career that spanned over six decades; he too would be known as the "man in the white hat,"--trusted to do the right thing. From 1967 to 1970,…

  20. Een man die acuut onrustig werd na contrasttoediening

    NARCIS (Netherlands)

    Tielbeek, Jeroen A. W.; de Waard, Stephanie N.; de Mol van Otterloo, Alexander

    2012-01-01

    A 63-year-old man attended the emergency room with lower back pain. An abdominal CT scan was scheduled. However, after intravenous injection of contrast, the patient became acutely agitated and his tension dropped. After a delay of two minutes the scan was performed and showed massive contrast