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Sample records for truu mait kriipsalu

  1. Mait Laas : see oli intrigeeriv eksperiment / Mait Laas

    Index Scriptorium Estoniae

    Laas, Mait, 1970-

    2006-01-01

    Kinos Sõprus on ekraanil Ida-Euroopa kuue noore režissööri filmiprojekt "Kaotatud ja leitud" ("Lost and Found"), mille seob tervikuks Mait Laasi nukufilm "Gene+Ratio". Režissöör räägib projektist lähemalt

  2. DOE contractor vulnerability analysis: DPA or MAIT

    International Nuclear Information System (INIS)

    Six, D.E.; Nichols, D.H.

    1980-01-01

    Two vulnerability analysis techniques, Diversion Path Analysis (DPA) and Matrix Analysis of the Insider Threat (MAIT), were applied by EG and G Idaho, Inc. Safeguards and Security to the same item accountable SNM storage area at INEL. Technical and cost data for each methodology were collected and compared. A recommendation that MAIT be utilized for future vulnerability analyses of item accountable SNM storage and use areas operated by EG and G Idaho for DOE-ID resulted. Unclassified results of the two techniques and MAIT/DPA technical and cost comparisons will be presented which show that MAIT can be used for vulnerability analyses to comply with Department of Energy (DOE) requirements

  3. Saku Suurhall Rocca Al Mares / Esa Viitanen, Andres Kariste, Meeli Truu...[jt.

    Index Scriptorium Estoniae

    2001-01-01

    5 joon.: asendiplaan, I, II korruse plaan, vaade läänest, transformeeritav saal ; 5 fotot, värv.: 2 välisvaadet, 3 sisevaadet ; peaprojekteerija, detailplaneering: Nord Projekt AS ; arhitektid E. Viitanen, A. Kariste, kaastöö: M. Truu, L. Raudsepp ; sisekujundus: ARS Interjöörprojekt

  4. Stepwise development of MAIT cells in mouse and human.

    Directory of Open Access Journals (Sweden)

    Emmanuel Martin

    2009-03-01

    Full Text Available Mucosal-associated invariant T (MAIT cells display two evolutionarily conserved features: an invariant T cell receptor (TCRalpha (iTCRalpha chain and restriction by the nonpolymorphic class Ib major histocompatibility complex (MHC molecule, MHC-related molecule 1 (MR1. MR1 expression on thymus epithelial cells is not necessary for MAIT cell development but their accumulation in the gut requires MR1 expressing B cells and commensal flora. MAIT cell development is poorly known, as these cells have not been found in the thymus so far. Herein, complementary human and mouse experiments using an anti-humanValpha7.2 antibody and MAIT cell-specific iTCRalpha and TCRbeta transgenic mice in different genetic backgrounds show that MAIT cell development is a stepwise process, with an intra-thymic selection followed by peripheral expansion. Mouse MAIT cells are selected in an MR1-dependent manner both in fetal thymic organ culture and in double iTCRalpha and TCRbeta transgenic RAG knockout mice. In the latter mice, MAIT cells do not expand in the periphery unless B cells are added back by adoptive transfer, showing that B cells are not required for the initial thymic selection step but for the peripheral accumulation. In humans, contrary to natural killer T (NKT cells, MAIT cells display a naïve phenotype in the thymus as well as in cord blood where they are in low numbers. After birth, MAIT cells acquire a memory phenotype and expand dramatically, up to 1%-4% of blood T cells. Finally, in contrast with NKT cells, human MAIT cell development is independent of the molecular adaptor SAP. Interestingly, mouse MAIT cells display a naïve phenotype and do not express the ZBTB16 transcription factor, which, in contrast, is expressed by NKT cells and the memory human MAIT cells found in the periphery after birth. In conclusion, MAIT cells are selected by MR1 in the thymus on a non-B non-T hematopoietic cell, and acquire a memory phenotype and expand in the

  5. Mait Agu nimelise tantsustipendiumi saab Janek Savolainen / Angela Arraste

    Index Scriptorium Estoniae

    Arraste, Angela, 1953-

    2000-01-01

    Mait Agu nim. tantsustipendium loodi 1999.a. Tallinna Pedagoogikaülikooli kultuuriteaduskonna koreograafia õppetooli ettepanekul. Stipendium antakse üliõpilasele, kes on eelneva aasta jooksul olnud edukas õppetöös ning osa võtnud erinevatest tantsulistest projektidest

  6. Kunstiülikool on nagu pioneeride palee kunstiring / Vilen Künnapu, Meeli Truu, Eerik Olle...[jt.] ; interv. Gea Velthut-Sokka

    Index Scriptorium Estoniae

    1999-01-01

    Arhitektid V. Künnapu ja M. Truu, sisearhitektid I.-E. Schneider, E. Olle ja M. Peri ning kinnisvaraarendaja A. Aavik vastavad küsimustele, millises ülikoolis nad omandaksid eriala, kui nad oleksi praegu tudengid, Eestis saadava hariduse konkurentsivõimelisuse kohta maailmas, mida nad tahaksid praegu enda täiendamiseks õppida?

  7. Conservation of mucosal associated invariant T (MAIT) cells and the MR1 restriction element in ruminants, and abundance of MAIT cells in spleen.

    Science.gov (United States)

    Goldfinch, Nick; Reinink, Peter; Connelley, Timothy; Koets, Ad; Morrison, Ivan; Van Rhijn, Ildiko

    2010-01-01

    MHC-related protein 1 (MR1) is a highly conserved MHC class I-like molecule. Human and murine mucosal associated invariant T (MAIT) cells are restricted by MR1 and express an invariant T cell receptor. Even though MR1 protein expression on the cell surface has not been demonstrated in vivo or ex vivo, it is assumed that MR1 presents a bacterial antigen from the intestinal lumen to MAIT cells because MAIT cells are present in the lamina propria and their expansion is dependent on the presence of intestinal micro flora. The existence of bovine MAIT cells and MR1 has been demonstrated recently although ovine MAIT cells and MR1 have not yet been described. We cloned bovine and ovine MR1 transcripts, including splice variants, and identified an anti human MR1 antibody that recognizes cells transfected with the bovine homolog. Using this antibody, no MR1 staining was detected using cells freshly isolated from blood, thymus, spleen, colon, ileum, and lymph node. MAIT cells are known to be enriched in the CD4/CD8 double negative peripheral blood T cell population, but their relative abundance in different tissues is not known. Comparison of the amount of MAIT cell-specific TCR transcript to the amount of constant alpha chain transcript revealed that numbers of MAIT cells are low in neonates and increase by 3-weeks of age. In 3-month old animals, MAIT cells are abundant in spleen and less so in ileum, peripheral blood, lymph node, colon, and thymus. © The authors, published by INRA/EDP Sciences, 2010.

  8. MAIT cells are activated in acute Dengue virus infection and after in vitro Zika virus infection.

    Science.gov (United States)

    Paquin-Proulx, Dominic; Avelino-Silva, Vivian I; Santos, Bianca A N; Silveira Barsotti, Nathália; Siroma, Fabiana; Fernandes Ramos, Jessica; Coracini Tonacio, Adriana; Song, Alice; Maestri, Alvino; Barros Cerqueira, Natalia; Felix, Alvina Clara; Levi, José Eduardo; Greenspun, Benjamin C; de Mulder Rougvie, Miguel; Rosenberg, Michael G; Nixon, Douglas F; Kallas, Esper G

    2018-01-01

    Dengue virus (DENV) and Zika virus (ZIKV) are members of the Flaviviridae and are predominantly transmitted via mosquito bites. Both viruses are responsible for a growing number of infections in tropical and subtropical regions. DENV infection can cause lethargy with severe morbidity and dengue shock syndrome leading to death in some cases. ZIKV is now linked with Guillain-Barré syndrome and fetal malformations including microcephaly and developmental disorders (congenital Zika syndrome). The protective and pathogenic roles played by the immune response in these infections is unknown. Mucosal-associated invariant T (MAIT) cells are a population of innate T cells with potent anti-bacterial activity. MAIT cells have also been postulated to play a role in the immune response to viral infections. In this study, we evaluated MAIT cell frequency, phenotype, and function in samples from subjects with acute and convalescent DENV infection. We found that in acute DENV infection, MAIT cells had elevated co-expression of the activation markers CD38 and HLA-DR and had a poor IFNγ response following bacterial stimulation. Furthermore, we found that MAIT cells can produce IFNγ in response to in vitro infection with ZIKV. This MAIT cell response was independent of MR1, but dependent on IL-12 and IL-18. Our results suggest that MAIT cells may play an important role in the immune response to Flavivirus infections.

  9. MAIT cells are activated in acute Dengue virus infection and after in vitro Zika virus infection.

    Directory of Open Access Journals (Sweden)

    Dominic Paquin-Proulx

    2018-01-01

    Full Text Available Dengue virus (DENV and Zika virus (ZIKV are members of the Flaviviridae and are predominantly transmitted via mosquito bites. Both viruses are responsible for a growing number of infections in tropical and subtropical regions. DENV infection can cause lethargy with severe morbidity and dengue shock syndrome leading to death in some cases. ZIKV is now linked with Guillain-Barré syndrome and fetal malformations including microcephaly and developmental disorders (congenital Zika syndrome. The protective and pathogenic roles played by the immune response in these infections is unknown. Mucosal-associated invariant T (MAIT cells are a population of innate T cells with potent anti-bacterial activity. MAIT cells have also been postulated to play a role in the immune response to viral infections. In this study, we evaluated MAIT cell frequency, phenotype, and function in samples from subjects with acute and convalescent DENV infection. We found that in acute DENV infection, MAIT cells had elevated co-expression of the activation markers CD38 and HLA-DR and had a poor IFNγ response following bacterial stimulation. Furthermore, we found that MAIT cells can produce IFNγ in response to in vitro infection with ZIKV. This MAIT cell response was independent of MR1, but dependent on IL-12 and IL-18. Our results suggest that MAIT cells may play an important role in the immune response to Flavivirus infections.

  10. MAIT cell clonal expansion and TCR repertoire shaping in human volunteers challenged with Salmonella Paratyphi A

    OpenAIRE

    Howson, Lauren J.; Napolitani, Giorgio; Shepherd, Dawn; Ghadbane, Hemza; Kurupati, Prathiba; Preciado-Llanes, Lorena; Rei, Margarida; Dobinson, Hazel C.; Gibani, Malick M.; Teng, Karen Wei Weng; Newell, Evan W.; Veerapen, Natacha; Besra, Gurdyal S.; Pollard, Andrew J.; Cerundolo, Vincenzo

    2018-01-01

    Mucosal-associated invariant T (MAIT) cells are innate-like T cells that can detect bacteria-derived metabolites presented on MR1. Here we show, using a controlled infection of humans with live Salmonella enterica serovar Paratyphi A, that MAIT cells are activated during infection, an effect maintained even after antibiotic treatment. At the peak of infection MAIT cell T-cell receptor (TCR)β clonotypes that are over-represented prior to infection transiently contract. Select MAIT cell TCRβ cl...

  11. MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage

    DEFF Research Database (Denmark)

    Gold, Marielle C.; McLaren, James E.; Reistetter, Joseph A.

    2015-01-01

    with this interpretation, MAIT cell clones with distinct TCRs responded differentially to a riboflavin metabolite. These results suggest that MAIT cells can discriminate between pathogen-derived ligands in a clonotype-dependent manner, providing a basis for adaptive memory via recruitment of specific repertoires shaped...

  12. MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage

    DEFF Research Database (Denmark)

    Gold, Marielle C.; McLaren, James E.; Reistetter, Joseph A.

    2014-01-01

    with this interpretation, MAIT cell clones with distinct TCRs responded differentially to a riboflavin metabolite. These results suggest that MAIT cells can discriminate between pathogen-derived ligands in a clonotype-dependent manner, providing a basis for adaptive memory via recruitment of specific repertoires shaped...

  13. Mait Agu nimelise stipendiumi pälvivad aastal 2013 Eliisa Sokk ja Ene Jakobson

    Index Scriptorium Estoniae

    2013-01-01

    Tallinna Ülikooli koreograafia osakond annab Mait Agu nimelist stipendiumi välja viieteistkümnendat korda. Stipendiumi saavad TLÜ koreograafia osakonna 3. kursuse tudeng Eliisa Sokk ja TLÜ koreograafia eriala 2. lennu lõpetaja, tantsuansambli "Sõleke" looja ning juht Ene Jakobson

  14. Taifuun nimega Valimised on möödas / Mait Klaassen

    Index Scriptorium Estoniae

    Klaassen, Mait, 1955-

    2005-01-01

    Ilmunud ka: Põhjarannik 20. okt., lk. 2, Severnoje Poberezhje 20. okt., lk. 2, Meie Maa 20. okt., lk. 2, Sakala 21. okt., lk. 2, Vali Uudised 21. okt. lk. 2, Koit, Järva Teataja 22. okt. lk. 6,2, Lääne Elu 25. okt., lk. 2, Harjumaa 25. okt. lk. 2, Vooremaa 27. okt. lk. 2. Parlamendisaadik, Reformierakonna liige Mait Klaassen teeb kokkuvõtte lõppenud kohalikest valimistest

  15. Programmeerimise alused / Ahto Truu

    Index Scriptorium Estoniae

    Truu, Ahto, 1972-

    2007-01-01

    Arvutiprogrammide koostamise põhimõtetest ja -võtetest. Järgneb nr. 2, lk. 52-53, nr. 3, lk. 50-52, nr. 4, lk. 50-52, nr. 5, lk. 52-53, nr. 6, lk. 52-53 ; 2008 nr. 1, lk. 50-52, nr. 2, lk. 52-53, nr. 3, lk. 47-49, nr. 4, lk. 47-49, nr. 5, lk. 48-49, nr. 6, lk. 48-49. Artiklid on erinevate pealkirjadega

  16. HIV infection is associated with preservation of MAIT cells in the lungs but alteration of their phenotype and T cell receptor repertoire

    DEFF Research Database (Denmark)

    Wong, E. B.; Xulu, B.; Prakadan, S.

    2016-01-01

    Tuberculosis remains the leading cause of death in HIV-positive people. A better understanding of the impact of HIV on lung immunity may lead to novel immunotherapeutic interventions. MAIT cells are tissue-homing donor-unrestricted T cells with broad anti-microbial activity. HIV infection causes...... early and irreversible depletion of MAIT cells in the peripheral circulation, but the effect of HIV on MAIT cells in the lungs is unknown. These researchers report, for the first time, that MAIT cells in the lungs are numerically preserved but phenotypically and clonotypically altered by HIV infection...... to determine the mechanisms underlying the altered phenotypes of lung-resident MAITs and whether these can be targeted to improve anti-microbial lung immunity in people living with HIV....

  17. Endosomal MR1 Trafficking Plays a Key Role in Presentation of Mycobacterium tuberculosis Ligands to MAIT Cells.

    Directory of Open Access Journals (Sweden)

    Melanie J Harriff

    2016-03-01

    Full Text Available Mucosal-Associated Invariant T (MAIT cells, present in high frequency in airway and other mucosal tissues, have Th1 effector capacity positioning them to play a critical role in the early immune response to intracellular pathogens, including Mycobacterium tuberculosis (Mtb. MR1 is a highly conserved Class I-like molecule that presents vitamin B metabolites to MAIT cells. The mechanisms for loading these ubiquitous small molecules are likely to be tightly regulated to prevent inappropriate MAIT cell activation. To define the intracellular localization of MR1, we analyzed the distribution of an MR1-GFP fusion protein in antigen presenting cells. We found that MR1 localized to endosomes and was translocated to the cell surface upon addition of 6-formyl pterin (6-FP. To understand the mechanisms by which MR1 antigens are presented, we used a lentiviral shRNA screen to identify trafficking molecules that are required for the presentation of Mtb antigen to HLA-diverse T cells. We identified Stx18, VAMP4, and Rab6 as trafficking molecules regulating MR1-dependent MAIT cell recognition of Mtb-infected cells. Stx18 but not VAMP4 or Rab6 knockdown also resulted in decreased 6-FP-dependent surface translocation of MR1 suggesting distinct pathways for loading of exogenous ligands and intracellular mycobacterially-derived ligands. We postulate that endosome-mediated trafficking of MR1 allows for selective sampling of the intracellular environment.

  18. Isepäine modernist Toomas Rein / Toomas Rein ; intervjueerinud Mait Väljas ja Reet Varblane

    Index Scriptorium Estoniae

    Rein, Toomas, 1940-

    2010-01-01

    23. aprillil avatakse Eesti Arhitektuurimuuseumis arhitekt Toomas Reinu 70. sünnipäevale pühendatud näitus. Kataloogi ja näituse on koostanud Toomas Rein ja Mait Väljas, kujundanud Tiit Jürna. Toomas Rein endast, oma loomingust, eeskujudest, näitusest, nõukogude perioodi hoonete olukorrast, viimase aja töödest, koostööst teiste arhitektidega, teostamata projektidest

  19. MAIT, MR1, microbes and riboflavin: a paradigm for the co-evolution of invariant TCRs and restricting MHCI-like molecules?

    Science.gov (United States)

    Mondot, Stanislas; Boudinot, Pierre; Lantz, Olivier

    2016-08-01

    MAIT cells express an invariant TCR that recognizes non-peptidic microbial antigens presented by the non-polymorphic MHCI-like molecule, MR1. We briefly describe how the antigens recognized by MAIT cells are generated from an unstable precursor of the riboflavin (Vitamin B2) biosynthesis pathway, as well as the main features of MAIT cells in comparison with other related T cell subsets. In silico analysis of bacterial genomes shows that the riboflavin biosynthesis pathway is highly prevalent in all groups of Prokaryotes with, however, notable exceptions. We discuss the putative functions and the evolution of the MAIT/MR1 couple: it appeared in the ancestors of mammals and is highly conserved across this group, but was independently lost in three orders. We describe the four instances of known invariant TCR and MHC-I-like molecules encountered in Vertebrates. Both T cells bearing semi-invariant TCR and the associated, evolutionarily conserved MHC-I related molecules have been found in mammals or in amphibians, which suggests that other MHC1-like/invariant TCR couples might be present in other classes of Vertebrates to detect generic microbial compounds. This allows us to discuss how the recognition of riboflavin precursor derivatives by the MAIT TCR may be a way to detect invasive microbes in specific organs, and may epitomize other invariant T cell systems across vertebrates.

  20. Tähed disainiöös / Mait Summatavet, Risto Räägel, Per Mollerup...[jt.] ; interv. Karin Paulus

    Index Scriptorium Estoniae

    2007-01-01

    Disainiöö raames avati Arhitektuuri- ja Disainigaleriis näitus "Kokkupandavad asjad" ning kuulutati välja konkursi võitjad. Peapreemia võitis läti disaineri Elina Bushmane kokkupandav teelaud, teise koha Jaana Päeva tekstiilist kott, kolmanda koha Ingrem Floreni käekott. Ära märgiti Veiko Liisi kilepiima vutlar. Disainiöö üritustest ning konkursitöödest räägivad Mait Summatavet, Per Mollerup, Simo Heikkilä, Risto Räägel

  1. MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression.

    Directory of Open Access Journals (Sweden)

    Christopher R Shaler

    2017-06-01

    Full Text Available Superantigens (SAgs are potent exotoxins secreted by Staphylococcus aureus and Streptococcus pyogenes. They target a large fraction of T cell pools to set in motion a "cytokine storm" with severe and sometimes life-threatening consequences typically encountered in toxic shock syndrome (TSS. Given the rapidity with which TSS develops, designing timely and truly targeted therapies for this syndrome requires identification of key mediators of the cytokine storm's initial wave. Equally important, early host responses to SAgs can be accompanied or followed by a state of immunosuppression, which in turn jeopardizes the host's ability to combat and clear infections. Unlike in mouse models, the mechanisms underlying SAg-associated immunosuppression in humans are ill-defined. In this work, we have identified a population of innate-like T cells, called mucosa-associated invariant T (MAIT cells, as the most powerful source of pro-inflammatory cytokines after exposure to SAgs. We have utilized primary human peripheral blood and hepatic mononuclear cells, mouse MAIT hybridoma lines, HLA-DR4-transgenic mice, MAIThighHLA-DR4+ bone marrow chimeras, and humanized NOD-scid IL-2Rγnull mice to demonstrate for the first time that: i mouse and human MAIT cells are hyperresponsive to SAgs, typified by staphylococcal enterotoxin B (SEB; ii the human MAIT cell response to SEB is rapid and far greater in magnitude than that launched by unfractionated conventional T, invariant natural killer T (iNKT or γδ T cells, and is characterized by production of interferon (IFN-γ, tumor necrosis factor (TNF-α and interleukin (IL-2, but not IL-17A; iii high-affinity MHC class II interaction with SAgs, but not MHC-related protein 1 (MR1 participation, is required for MAIT cell activation; iv MAIT cell responses to SEB can occur in a T cell receptor (TCR Vβ-specific manner but are largely contributed by IL-12 and IL-18; v as MAIT cells are primed by SAgs, they also begin to

  2. Truu armastuse võimalikkusest / Jaan Ruus

    Index Scriptorium Estoniae

    Ruus, Jaan, 1938-2017

    2005-01-01

    Mängufilm "Madisoni maakonna sillad" ("The Bridges of Madison County") : stsenarist Robert James Walleri romaani põhjal Richard LaGravenese : režissöör ja peaosatäitja Clint Eastwood : Ameerika Ühendriigid 1995

  3. Plaadid / Mait Eelrand

    Index Scriptorium Estoniae

    Eelrand, Mait, 1950-

    2006-01-01

    Uutest heliplaatidest JJ CAle & Eric Clapton "The Road To escondido", Fergie "The Dutchess", Cosmoskva "Juniper", "The Devil Wears Prada", Peaches "Impeach My Bush", Ludacris "Release Therapy", Milburn "Well Well Well"

  4. Increased Tryptophan Catabolism is Associated with Increased Frequency of CD161+Tc17/MAIT Cells, and Lower CD4+ T cell Count in HIV-1 infected Patients on cART after Two Years of Follow-up

    DEFF Research Database (Denmark)

    Gaardbo, Julie Christine; Trøseid, Marius; Stiksrud, Birgitte

    2015-01-01

    of KTR on CD4+ T cell recovery in HIV-infected patients on cART after two years of follow-up was investigated. METHODS: Forty-one HIV-infected individuals treated with cART for a minimum of two years were included. Tregs, CD161+Tc17/MAIT cells, naïve cells, immune activation, senescence and apoptosis...... divided in two groups defined by high vs. low KTR. The CD4+ T cell count was determined at inclusion and after two years of follow-up. RESULTS: The KTR decreased following cART initiation. Patients on cART with high KTR displayed an immunological profile with high sCD14, high percentage Tregs, low...... percentage CD161+Tc17/MAIT cells, low percentage naïve cells, low CD4/CD8 ratio and poor immune reconstitution after two years of follow-up compared to patients with low KTR. CONCLUSIONS: Our results support the hypothesis that tryptophan catabolism, Indoleamine 2,3-dioxygenase 1 (IDO1) activation, microbial...

  5. Eesti taluperenaine kolhooside maal / A. Tenson ; refereerinud Tiia Truu

    Index Scriptorium Estoniae

    Tenson, A.

    2009-01-01

    Kolhooside asutamisest, elust ja tööst kolhoosis Venemaal eestlase silmade läbi. Jõukamate talupidajate hulka kuulunud Venemaal elanud eestlaste ja nende talude saatusest, endise taluperenaise elust kolhoosis, koolidest. Vastuhakanute elust sunnitööl

  6. Tõeline arhitektuur kolis linnast Juuru valda / Tiia Truu

    Index Scriptorium Estoniae

    Truu, Tiia, 1948-

    2005-01-01

    Arhitektuurivõistlusest, mille eesmärgiks oli saada parim lahendus Mahtra muuseumi laiendamiseks. Esimene preemia - märgusõna "Heinamaa", Tomomi Hayashi ja Hanno Grossschmidt arhitektuuribüroost HG Arhitektuur. Teine preemia - märgusõna "Talgud", Andres Lember ja Tarmo Maiste arhitektuuribüroost Male Arhitektid. Kolmas preemia - märgusõna "Pärand", arhitekt Liina Jaanus

  7. Birma - otsekui retk minevikku / Mait Talts

    Index Scriptorium Estoniae

    Talts, Mait, 1964-

    2011-01-01

    Reisist Birmasse, tänapäevase nimega Myanmari, mida Eestiga seovad sinna maetud "Eestimaa budistlikud peapiiskopid" Karl A.M. Tõnisson-Tennisons (Vend Vahindra, 1883-1962) ja Friedrich Voldemar Lustig (Ashin Ananda, 1912-1989)

  8. Valitsemise ilu ja valu / Mait Klaassen

    Index Scriptorium Estoniae

    Klaassen, Mait, 1955-

    2005-01-01

    Ilmunud ka: Severnoje Poberezhje 26. apr., lk. 2, Lääne Elu 26. apr., lk. 2, Vali Uudised 27. apr., lk. 2, Meie Maa 27. apr. lk. 2, Nädaline, Koit 28. apr. lk. 4,6, Türi Rahvaleht 29. apr., lk. 4, Hiiu Leht 29. apr., lk. 2, Harjumaa 29. apr. lk. 2, Valgamaalane 3. mai lk. 2, Sakala 6. mai lk. 2, Pärnu Postimees 7. mai lk. 19, Paremad Uudised mai nr. 4 lk. 7. Uue valitsuse koalitsioonileppest

  9. Raske tervisekahjustuse tekitamise katse. Riigikohtu kriminaalkolleegiumi otsus asjas 3-1-1-111-16 / Mario Truu

    Index Scriptorium Estoniae

    Truu, Mario, 1989-

    2017-01-01

    Riigikohtu kriminaalkolleegiumi otsusest asjas 3-1-1-111-16, teo toimepanija tahtlusest raske tervisekahjustuse tekitamise katse korral. Tervisekahjustuse liigi ja raskuse tuvastamisest kriminaalkohtumenetluses

  10. Kes räägib tõtt, kes ebatõtt? / Elmar Truu

    Index Scriptorium Estoniae

    Truu, Elmar-Johannes, 1942-

    2001-01-01

    Ilmunud ka: Sakala, 27. nov. 2001, lk. 2; Meie Maa, 28. nov. 2001, lk. 2; Valgamaalane, 27. nov, 2001, lk. 2; Virumaa Teataja, 28. nov. 2001, lk. 7; Nädaline, 29. nov. 2001, lk. 4; ERL Teataja, dets. 2001, nr. 12, lk. 4. Riigikogu 14. nov. infotunnis pöördumisest sotsiaalministri Eiki Nestori poole küsimustega ravimite hinna järjekindlast tõstmisest. Autor: ERL. Parlamendisaadik

  11. Ellen Aitsam - õpetaja kõige paremas mõttes / Tiia Truu

    Index Scriptorium Estoniae

    Truu, Tiia

    2007-01-01

    Persoonilugu 33 aastat Vigalas keemia-, biloogia- ja geograafiaõpetajana töötanud Ellen Aitsamist. Mare Mursak-Ülemaante; Jaan Moor; Evi Tikerpalu-Andrejev; Elme Tiits-Moor: Mis meenub õpetaja Ellen Aitsamist?

  12. Segarühm Kehtna Noored sündis soovist tantsida / Tiia Truu, Heino Laiapea

    Index Scriptorium Estoniae

    Truu, Tiia, 1948-

    2009-01-01

    Tänavusel laulu- ja tantsupeol ÜhesHingamine osalevate kollektiivide tutvustus. Rahvatantsurühmast Kehtna Noored (juhendaja Mall Niinemets), Valtu põhikooli võimlejatest (juhendaja Kadi Saks), rahvatantsurühmast Kärutajad (juhendaja Valdo Rebane), Kehtna segakoorist (dirigent Ülle Eerik), Kehtna valla lastekoorist (dirigendid Lea Karjane ja Ea Hark)

  13. Plaadid / Mait Eelrand, Toomas Puna, Veiko Pesur...[jt.

    Index Scriptorium Estoniae

    2007-01-01

    Uutest heliplaatidest Wolf & Cub "Vessels", Karl MAdis & Karavan "Taevalik meloodia ئ Nat King Cole'i laule", Sophie Ellis-Bextor "Trip The Light Fantastic", Him "Uneasy Listening 1&2", Kognito "Muutuv"

  14. Põhjamaade põlisvähemuste omakeelsest meediast / Mait Talts

    Index Scriptorium Estoniae

    Talts Mait, 1964-

    2009-01-01

    Artikkel jätkab Läänemere-äärsete etniliste vähemuskultuuride käsitlust. Vt. ka Haridus 5/6 2008, "Põlisvähemuskultuuride meediamaastikult" (latgalite, liivlaste, karaiimide, väikeleedulaste, kašuubide jt. omakeelse meedia hetkeolukorrast ja arenguperspektiividest)

  15. Teadusmõtte ja teaduse mineviku lood / Mait Talts

    Index Scriptorium Estoniae

    Talts, Mait, 1964-

    2011-01-01

    Arvustus: Baltic Journal of European Studies. Selected papers of the 24th International Baltic Conference on the history of science and the follow-up seminar (2011, nr. 1). Tallinn : Tallinn University of Technology, 2011

  16. Rotermanni soolalao urbanistliku pargi ideekonkurss / Mait Väljas

    Index Scriptorium Estoniae

    Väljas, Mait

    2009-01-01

    Eesti Arhitektuurimuuseumi korraldatud avalikust konkursist, Ignar Fjuki koostatud võistlustingimustest, premeeritud töödest. 1. preemia sai töö "Piazza", autor Villem Tomiste, (AB Kosmos)), 2. preemia töö "Muesuum", autor Ott Kadarik, (AB Kosmos), 3. preemia töö "Arhitektuuri allee", autor Jürgen Lepper, (AB Dimensioon). Anti välja üks ergutuspreemia, ära märgiti kaks tööd

  17. Wallenbergide Investor jätkab kasvustrateegiat / Olev Mait Makk

    Index Scriptorium Estoniae

    Makk, Olev Mait

    2001-01-01

    Wallenbergide kontrollitavast Rootsi investeerimisfirmast Investor, mille omanduses olevad firmad moodustavad kokku Euroopa suurima tööandja erasektoris. Investori gruppi kuuluvast ettevõttest SEB. Tabel: Investori portfellis olevad aktsiad; investori teenused tütarettevõtetele

  18. Finskii grafitsheskii beton teper takzhe i v Estonii / Mait Eelrand

    Index Scriptorium Estoniae

    Eelrand, Mait

    2007-01-01

    Graafilise betooni meetodi arendas 1990. aastate lõpul välja soome sisearhitekt Samuli Naamanka, tehnoloogia on patenteerinud tema asutatud firma Graphic Concrete Oy. AS E-Betoonelement kasutas graafilise betooni tehnoloogiat esimesena Rakveres büroohoone fassaadi kujundamiseks. Kommenteerivad Graphic Concrete Oy tegevdirektor H. Lanningu ja K. Meus AS-st E-Betoonelement

  19. Arhitektuurivõistlused 2008 / Mait Väljas

    Index Scriptorium Estoniae

    Väljas, Mait

    2008-01-01

    Võistluste tulemused: Pekingi saatkonnahoone: I preemia - A. Põime, L. Põime, L. Vaimel; Riia saatkonnahoone: I - L.-K. Stöör, Ü.-T. Stöör, H. Urb; Eesti Kunstiakadeemia uus õppehoone: I - SEA + Effekt (Taani); Eesti Maaülikooli Kreutzwaldi 5 õppehoone juurdeehitis: I - P. Loo, J. Skolimowski, L. Vene, K. Kruuse (KAMP Arhitektid); TÜ Viljandi Kultuuriakadeemia loomeinkubaatori ja lavakunstide õppehoone: I - S. Vallner, H. Urb, I. Peil, H. Lass, S.-M. Mändmaa (Kavakava); Tamula järve ranna-ala mahuline planeering: I - K. Enno, L. Luhse, M. Zeleznova, R. Ailt (K. Enno Arhitektuuribüroo); Tartu pärmivabriku kvartali arhitektuurivõistlus: võidutöö - Atelier Thomas Pucher / Bramberger Architects (Austria); Paldiski mnt. 50 kinnistu ja lähiala: I-II - T. Laigu, K. Ojaliiv, M. Rass, A. Uukado (QP Arhitektid); maastikuarhitektuuri võistlus "Eesti Maaülikooli Tähtvere linnaku välialad": I - H. Runnel, T. Ong; Tartu rahu tähisala kujundus: I - M. Kinks, K. Süda; Veneetsia XI rahvusvahelise arhitektuuribiennaali ideekavandi võistlus: I - M. Kask, R. Lõoke, N. Külm; aasta betoonehitis 2007 - Puurmani kaarsild, konstruktorid S. Idnurm, J. Idnurm; Eesti parim puitehitis 2008: eramu Loobul - R. Vaiksoo; võistluse "Eramu 2006-2007" peapreemia: villa Paldiskis - S. Vallner, I. Peil

  20. The singing revolution : part II-III / Mait Ando Raun

    Index Scriptorium Estoniae

    Raun, Mait, 1963-

    2000-01-01

    Tartu rahu ja vabariigi aastapäeva tähistamisest 1988. aastal; Sündmused veebruarist aprillini 1988: üliõpilaste demonstratsioonist veebruaris, Loominguliste Liitude ühispleenumist, Rahvarinde loomisest ja Tartu muinsuskaitsepäevadest aprillis. Järg nr.4, lk.70-73

  1. Katse portreteerida nõukogude kosmosemaja / Mait Väljas

    Index Scriptorium Estoniae

    Väljas, Mait

    2011-01-01

    Prantsuse fotograafist Frédéric Chaubinist, kes pildistas NSV Liidus 1975.-1990. a. ehitatud eripäraseid hooneid, korraldas fotonäitusi. F. Chaubini raamatust "СССР : cosmic communist constructions photographed" (Köln : Taschen, 2011), raamatusse jõudnud eesti arhitektuurist

  2. Tornimäe kaksiktornid Tallinnas. Konkursi "Aasta betoonehitis 2007" nominent / Meeli Truu, Juhan Idnurm, Jaan Port...[jt.

    Index Scriptorium Estoniae

    2008-01-01

    AS Nord Projekt; konstruktorid: Juhan Idnurm, Jaan Port, Kaido Kuusiku (Nord Projekt AS), Indrek Heinloo (E-Inseneribüroo OÜ), Matis Teeäär (Neoprojekt OÜ), Kaido Pärl (TAA-Konsult); ehitajad: Lemminkäinen Eesti AS, AS Merko Ehitus; betooni ja betoonelementide tarnijad: AS Rudus Eesti, AS Betoneks

  3. Mait-Väinu Sooäär : soigumist ma pole ära õppinud / Mait-Väinu Sooäär ; interv. Heli Salong

    Index Scriptorium Estoniae

    Sooäär, Mait-Väinu

    2006-01-01

    Endine KEK-i tippjuht, Kingissepa Rajooni Täitevkomitee esimehe ja Saare maavanema asetäitja, ärimees, kes praegu projekteerib reoveepuhasteid ja annab konsultatsioone vastab küsimustele oma karjäärist, õpingutest ja eraelust

  4. Üliõpilaste teadustööde konkurss / Anu Taprimäe

    Index Scriptorium Estoniae

    Taprimäe, Anu

    2000-01-01

    Tallinna Pedagoogikaülikooli üliõpilaste teadustööde konkursil said preemiad humanitaarteaduste komisjonilt: peapreemia Priit Ratassepp bakalaureusetöö "A.H.Tammsaare "Põrgupõhja uus Vanapagan" narratiivi teksti ja seda moodustavate kõnetegude analüüs" eest. Preemiad said veel Sergei Dotsenko, Mait Laas, Tiiu Männiste, Heidi Meier, Risto Paju, Margit Peenoja, Dimitri Mironov, Janek Innos, Kairi Reiter ja Maria Erss. Tallinna Pedagoogikaülikooli üliõpilaste teadustööde konkursil said preemiad geo- ja bioteaduste komisjonilt: Helen Orav, Reimo Rivis, Kaire Torn, Egle Hollman, Krister Põllupüü, Allan Lorents, Merle Kerde, Hele Kiimann, Hannes Tõnisson, Roland Müür; täppisteaduste komisjonilt: Astrid Haljas, Tambet Lember, Tiina Sard, Svetlana Malahhova, Moonika Veimer, Marge Lõuke, Margo Engel, Kadri Kalm, Kersti Truu; sotsiaalteaduste komisjonilt: Endel Põder, Erik Juzykain, Ly Kästik, Kadri Kütt, Kristiina Uriko, Teele Kaldoja, Marika Asberg, Riina Raun, Birgit Villa, Larissa Kus, Kristi Klaasmägi; kasvatusteaduste komisjonilt: Aina Haljaste, Triin Jaanisk, Reelika Rannala, Ermo Soobik, Moonika Nerman, Liina Tamm, Aet Soosaar, Kadri Ummus; sporditeaduste komisjonilt: Rain Rosin, Kristin Randver, Indrek Rannama

  5. Kulu- ja turupõhisest hinnakujundamise strateegiast turunduses / Mait Miljan, Kalev Kaarna

    Index Scriptorium Estoniae

    Miljan, Mait

    2005-01-01

    Tänapäevases ärikeskkonnas soovitavad autorid kasutada kombineeritud mudelit, milles rakendatakse kulu- ja turupõhist strateegiat lähtuvalt ettevõtte turusituatsioonist, tegevusvaldkonnast ning püütakse liikuda ühtse hinnakujundamiseni tarneahelas kui tervikus. Skeemid

  6. Tagasisidet peab töötajale vahendama ülemus / Mait Raava

    Index Scriptorium Estoniae

    Raava, Mait

    2004-01-01

    Autor teeb lühiülevaate 360ʻ ja teiste tagasiside meetodite rakendamisest maailmas alates 1950ndatest aastatest ning juhib tähelepanu vigadele, mida meetodi rakendamisel on tehtud. Kommenteerib Irene Metsis. Skeem: Juht saab tagasiside nelja kanali kaudu. Vt. samas: Rollist tulenevalt on tagasiside erinev

  7. Turuanalüüs - eduka turunduse juhtimise üks võtmetegur / Mait Miljan

    Index Scriptorium Estoniae

    Miljan, Mait

    2002-01-01

    Ettevõtte turunägemuse kujundamisel puutub kokku selliste mõistetega nagu turu definitsioon, turu arenguindeks (Market - MDI), turupotentsiaal, turunõudlus, turuosa arenguindeks (Share Development Index - SDI). Diagrammid

  8. NOMAD on the ExoMars TGO 2016 mission: MAIT and characterisation testing

    Science.gov (United States)

    Vandaele, Ann C.; Neefs, Eddy; Lopez-Moreno, J. J.; Rodriguez Gomez, Julio; Drummond, Rachel; Patel, Manish; Thomas, Ian; Gissot, Samuel; Depiesse, Cedric; Ben Moussa, Ali; Giordanengo, Boris; Bellucci, Giancarlo

    NOMAD, the “Nadir and Occultation for MArs Discovery” spectrometer suite has been selected by ESA and NASA to be part of the payload of the ExoMars Trace Gas Orbiter mission 2016. This instrument suite will conduct a spectroscopic survey of Mars’ atmosphere in the UV, visible and IR regions covering the 0.2-0.65 and 2.2-4.3 μm spectral ranges. NOMAD’s observation modes include solar occultation, nadir and limb observations. The NOMAD instrument is composed of 3 channels: a solar occultation only channel (SO) operating in the infrared wavelength domain, a second infrared channel capable of observing nadir, solar occultation and limb observations (LNO), and an ultraviolet/visible channel (UVIS) that can work in all observation modes. The spectral resolution of SO and LNO surpasses previous surveys in the infrared by more than one order of magnitude. NOMAD offers an integrated instrument combination of a flight-proven concept (SO is a copy of SOIR on Venus Express), and innovations based on existing and proven instrumentation (LNO is based on SOIR/VEX and UVIS has heritage from the ExoMars lander), that will provide mapping and vertical profile information at high spatio-temporal resolution. The three channels have each their own ILS and optical bench, but share the same single interface to the S/C. The NOMAD flight model is due for delivery to ESA in January 2015. We will present results so far of the manufacturing, assembly and especially testing of the various components. The UV CCDs have been characterised in thermal-vacuum; optical fibres have been studied with UV exposure to look at transmission degradation; the IR AOTFs have been tested for their transfer functions; lifetime and vibration testing has been carried out on the flip mirror mechanism. These are all vital inputs to the scientific results from NOMAD. Acknowledgements - The research program was supported by the Belgian Federal Science Policy Office and the European Space Agency (ESA PRODEX program). IAA participation is funded by MICIIN through Plan Nacional Ref. AYA2009-08190. UVIS support provided by the Open University and partly by STFC. Italian participants acknowledge the support from ASI.

  9. MAIT cells are activated in acute Dengue virus infection and after in vitro Zika virus infection

    OpenAIRE

    Paquin-Proulx, Dominic; Avelino-Silva, Vivian I.; Santos, Bianca A. N.; Silveira Barsotti, Nathália; Siroma, Fabiana; Fernandes Ramos, Jessica; Coracini Tonacio, Adriana; Song, Alice; Maestri, Alvino; Barros Cerqueira, Natalia; Felix, Alvina Clara; Levi, José Eduardo; Greenspun, Benjamin C.; de Mulder Rougvie, Miguel; Rosenberg, Michael G.

    2018-01-01

    Dengue virus (DENV) and Zika virus (ZIKV) are members of the Flaviviridae and are predominantly transmitted via mosquito bites. Both viruses are responsible for a growing number of infections in tropical and subtropical regions. DENV infection can cause lethargy with severe morbidity and dengue shock syndrome leading to death in some cases. ZIKV is now linked with Guillain-Barré syndrome and fetal malformations including microcephaly and developmental disorders (congenital Zika syndrome). The...

  10. MAIT cells are activated in acute Dengue virus infection and after in vitro Zika virus infection.

    OpenAIRE

    Dominic Paquin-Proulx; Vivian I Avelino-Silva; Bianca A N Santos; Nathália Silveira Barsotti; Fabiana Siroma; Jessica Fernandes Ramos; Adriana Coracini Tonacio; Alice Song; Alvino Maestri; Natalia Barros Cerqueira; Alvina Clara Felix; José Eduardo Levi; Benjamin C Greenspun; Miguel de Mulder Rougvie; Michael G Rosenberg

    2018-01-01

    Dengue virus (DENV) and Zika virus (ZIKV) are members of the Flaviviridae and are predominantly transmitted via mosquito bites. Both viruses are responsible for a growing number of infections in tropical and subtropical regions. DENV infection can cause lethargy with severe morbidity and dengue shock syndrome leading to death in some cases. ZIKV is now linked with Guillain-Barré syndrome and fetal malformations including microcephaly and developmental disorders (congenital Zika syndrome). The...

  11. Meduus Riia rannas / Galina Timtšenko ; intervjueerinud Mihhail Trunin ; tõlkinud Mait Eelrand

    Index Scriptorium Estoniae

    Timtšenko, Galina

    2016-01-01

    Intervjuu veebiväljaande Lenta.ru endise peatoimetaja, portaali Meduza looja ja peadirektori Galina Timtšenkoga veebilehest Meduza, ajakirjanduse arengusuundadest ning Baltimaades tegutsevate venekeelsete massiteabevahendite iseärasustest

  12. Oluline teatmeteos, mis võinuks olla veelgi parem / Mait Talts

    Index Scriptorium Estoniae

    Talts, Mait, 1964-

    2010-01-01

    Arvustus: Eesti perioodika 1941-1944 = Estnische Periodika 1941-1944 = Periodicals in Estonia 1941-1944 = Эстонская периодика 1941-1944 / Eesti Rahvusraamatukogu ; koostanud Külli Kaunissaar. Tallinn, 2009. (Eesti retrospektiivne rahvusbibliograafia)

  13. Eesti - oma juhtide peegel / Ari Vatanen ; tõlk. Mait Eelrand

    Index Scriptorium Estoniae

    Vatanen, Ari

    2008-01-01

    Euroopa Parlamendi liige toob president Toomas Hendrik Ilvest eeskujuks samuti sotsiaaldemokraatlikust erakonnast pärinevale Soome presidendile Tarja Halonenile. Autor kritiseerib president T. Haloneni seisukohti julgeolekupoliitika ja NATOga liitumise küsimustes ning tõstab esile president T. H. Ilvese jõulisi seisukohavõtte inimõiguste, demokraatia ja õigusriigi kaitsel. Lisatud Hillar Metsa karikatuur presidentidest Lennart Merist ja Toomas Hendrik Ilvesest. Vt. ka: Kaalukas Eesti. Päevaleht Online'i kommentaatorite vastukajad artiklile 22. mai 2008 Eesti Päevalehes lk. 2. Ilmunud ka: Vaba Eesti Sõna 22. mai 2008, lk. 3, 10

  14. Soomlaste graafiline betoon nüüd ka Eestis / Mait Eelrand

    Index Scriptorium Estoniae

    Eelrand, Mait

    2007-01-01

    Graafilise betooni meetodi arendas 1990. aastate lõpul välja soome sisearhitekt Samuli Naamanka, tehnoloogia on patenteerinud tema asutatud firma Graphic Concrete Oy. AS E-Betoonelement kasutas graafilise betooni tehnoloogiat esimesena Rakveres büroohoone fassaadi kujundamiseks. Kommenteerivad Graphic Concrete Oy tegevdirektor H. Lanningu ja K. Meus AS-st E-Betoonelement

  15. Hea võistluse saladus ehk 12 vakka tangusoola / Mait Tõnisson

    Index Scriptorium Estoniae

    Tõnisson, Mait, 1973-

    2010-01-01

    EOL üldkogul Eesti 2009. aasta parimaks orienteerumisvõistluseks valitud LSF Pronoking Teaḿi ja Rakvere OK poolt 03.-04. oktoobril 2009 Kuusalus toimunud XXII(!) [p.o XXI] Suunto Gameśi korraldamisest ja ettevalmistamisest

  16. Protsessid, mitte objekid : arhitektuurilõpetajad'07 / Mait Väljas

    Index Scriptorium Estoniae

    Väljas, Mait

    2007-01-01

    2007. a. Eesti Kunstiakadeemia arhitektuuri ja linnaplaneerimise eriala magistritöödest (Rene Sauemägi kavandatud Tallinna uus raekoda Admiraliteedi basseini ääres, Villu Scheleri kavandatud TÜ tehnoloogialinnakus Tartus, Kai Kuusiku "Valglinna avalik ruum", Ülo-Tarmo Stööri "Võimaluste linn", Hannes Koppeli Keilasse planeeritavat uut maanteelahendust vaatlev töö, Pelle-Sten Viiburgi "Tabasalu planeering", Sander Aasa "Pakri saare koloniseerimine", Margit Kärneri "Meremaastikud. Mereplaneerimisest ja inimtegevuse võimalikkusest veel")

  17. Majad ja muutumised marsruudil JPN-USA-EST / Tomomi Hayashi ; intervjueerinud Mait Väljas

    Index Scriptorium Estoniae

    Hayashi, Tomomi, 1971-

    2011-01-01

    Intervjuu Jaapanis Toyamas sündinud ning Eestis elava ja töötava arhitekti Tomomi Hayashiga, kes aastast 2004 on HG Arhitektuur OÜ arhitekt ja partner. Endast, tööst New Yorgis Rafael Viñoly büroos, Eestisse tulekust, oma tööpõhimõtetest, lemmikarhitektidest, järgmisest ehitusbuumist jm. Loetletud T. Hayashi töid, preemiad

  18. Applying theory of constraints in tactical and strategic management / Kalev Kaarna, Mait Miljan

    Index Scriptorium Estoniae

    Kaarna, Kalev

    2002-01-01

    Bibliogr. lk. 86-87. - Kokkuvõte eesti keeles lk. 87. Piirangute teooria kasutamise vajadusest ja võimalustest. Piirangute juhtimisest pikas perspektiivis ning sellel põhinevast strateegilisest juhtimisest. Tabelid

  19. Hermann Namsing pühendus ühistegevusele / Mait Talts

    Index Scriptorium Estoniae

    Talts, Mait, 1964-

    2003-01-01

    Viljandis sündinud ning ühistegevuse, ajakirjanduse, rahvahariduse ja lastekirjandusega tegelenud Hermann Namsingust (1878-1924). Rahumäe kalmistul oleva Herman Namsingu hauamonumendi autor on Jaan Koort

  20. Grand Prix' võitis reklaamfilmistuudio Division / Mait Laas, Jaak Lõhmus, Ants Vist...[jt.] ; interv. Tiiu Leis

    Index Scriptorium Estoniae

    1998-01-01

    Pärnu filmipäevadel 'Do Re Vi' võitis Grand Prix ehk skulptuuri 'Oskar & Ella' reklaamistuudio 'Division', kullatud videokassetid said 'Polarfilm' (dok. film), Martin Pedanik (video) ja Edith Sepp ('Tingimustega Tallinnas'); osalejate M. Laasi, J. Lõhmuse, A. Visti ja I. Raagi kommentaare ürituse kohta;

  1. Kangelane ja kaabakas: kuulsad kuningad muistse LähisIda ja Kreeka pärimustes / Mait Kõiv

    Index Scriptorium Estoniae

    Kõiv, Mait, 1961-

    2015-01-01

    Mesopotaamia, Pärsia ja Vana-Kreeka kolmest olulisest dünastiast. Akkadi kuningatest - Sargon'ist ja Naram-Sin'ist, Pärsia kuningatest Kyros'est ja Kambyses'est. Korintose türannidest Kypselos'est ja Periandros'est. Pärimuse tagamaadest: müütidest, propagandast ja reaalsusest. Dünastia rajaja kujutamisest kangelasena ja dünastia viimase esindaja demoniseerimisest

  2. 2013. aasta preemiate žürii kommentaar = Comments from 2013 annual prize panel of judges / Mait Väljas

    Index Scriptorium Estoniae

    Väljas, Mait

    2015-01-01

    Eesti kultuurkapitali aastapreemia 2013 Tartu Ülikooli Narva Kolledžile. Arhitektuuri sihtkapitali arhitektuuripreemia Viljandi Riigigümnaasiumile, arhitektuuri eripreemia Kukemõisa karjamõisale, sisearhitektuuripreemia Tallinna Ülikooli BFMi õppehoonele, maastikuarhitektuuripreemia Eesti Ajaloomuuseumi väliekspositsioonile "Klooga laager ja holokaust", innovatsioonipreemia Passion House moodulmajale, arhitektuurialase tegevuse preemia Triin Ojarile ja disainipreemia Matti Õunapuule roller Stigo eest

  3. Sloveenia arhitektuurist / Andrej Hrausky, Aljoša Dekleva, Tina Gregorič ; intervjueerinud Mait Väljas

    Index Scriptorium Estoniae

    Hrausky, Andrej

    2011-01-01

    Sloveenia kaasaegse arhitektuuri näitus Eesti Arhitektuurimuuseumis 21. aug.-ni 2011. Eksponeeritud 36 objekti on valminud vahemikus 1999-2009. Näituse kuraatorid: Andrej Hrausky, Maja Ivanič. 7. juulil andis arhitekt Andrej Hrausky ülevaate Sloveenia 20. sajandi arhitektuurist, Aljoša Dekleva ja Tina Gregorič tutvustasid oma loomingut. Intervjuu arhitektidega, ka nende muljeid eesti arhitektuurist

  4. Audentese Ülikooli Toimetiste ajaloolistele küsimustele pühendatud number / Mait Talts

    Index Scriptorium Estoniae

    Talts, Mait, 1964-

    2007-01-01

    Valdavalt ajaloole pühendatud alaseeria "Poliitika, riigiteadus ja rahvusvahelised suhted" kaheksandast numbrist. Lähemalt Jaak Lensmendi esseest "Liberaalne Euroopa ja tema moslemid", Paul Goble'i artiklist "Venemaa impeeriumi ja rahvusriigi vahel" ning Eduard Raska artiklist "Kriminaalpoliitika müüdid ja tegelikkus"

  5. Selles töös oli kaks õudust : vangla ja tants / Mait Malmsten ; interv. Tiina Ansip

    Index Scriptorium Estoniae

    Malmsten, Mait

    2005-01-01

    Näitleja räägib oma tööst ja rollist rahvusvahelises ühistöös valminud tantsufilmis "Teine" ("Another") : režissöör Rene Vilbre : koreograaf ja peaoaline Helena Jonsdottir. Filmi võtted toimusid Tartu vanglas

  6. Eesti otsib globaalsel kinnisvaraturul oma kohta. Kas Tallinn on naabritest parim? / Olev Mait Makk ; intervjueerinud Lemmi Kann

    Index Scriptorium Estoniae

    Makk, Olev Mait

    2011-01-01

    Intervjuu Cannes'is globaalsel kinnisvaramessil ja konverentsil MIPIM 2011 viibinud Seven Real Estate Advisors partneri, investeeringute ja nõustamisvaldkonna juhiga. Kinnisvara puhul on välisinvestorite poolt eelistatud sihtriik nn. uue Euroopa riikide seas Poola. Välisinvestorite suurim huvi Eestis on stabiilset rahavoogu tootvate büroo- ja kaubanduskeskuste vastu

  7. Kas kõik üliõpilaskohad peaksid olema tasulised? / Mart Susi, Talis Bachmann, Mait Arvisto ... [jt.

    Index Scriptorium Estoniae

    2000-01-01

    Vastavad Concordia Ülikooli, Õigusinstituudi, Tallinna Pedagoogikaülikooli, EPMÜ, Humanitaarinstituudi, Tartu Ülikooli, Eesti Mereakadeemia, Eesti Kunstiakadeemia, Eesti Muusikaakadeemia ja Tallinna Tehnikaülikooli rektorid

  8. Kesklinna politseihoone = The Central Tallinn Police Department / Margit Mutso

    Index Scriptorium Estoniae

    Mutso, Margit, 1966-

    2010-01-01

    Tallinnas Kolde pst. 65 asuva Kesklinna politseihoone arhitektuursest lahendusest. Arhitekt, sisearhitekt Meeli Truu, kaasautor Gersti Siimon (AS Nord Projekt). Žürii liikme Kalle Komissarovi hinnang kultuurkapitali aastapreemiale esitatud hoonele

  9. Restoran Cha Dao = Restaurant Cha Dao

    Index Scriptorium Estoniae

    2012-01-01

    Tallinnas Suur-Patarei 2 asuva Hiina restorani Cha Dao sisekujundusest. Restorani mööbel, v.a toolid, projekteeriti eritellimusena. Sisearhitekt Dmitri Pisarenko (DM3 OÜ), loetletud tema töid. Arhitekt Meeli Truu

  10. Projekteerijad kujundasid endale sobiva büroomaja / Aivo Vahemets

    Index Scriptorium Estoniae

    Vahemets, Aivo

    2005-01-01

    Projekteerimisfirma Nord Projekti ja ehitusettevõtte NCC Ehituse büroohoonest Tallinnas. Arhitektid Meeli Truu ja Andres Kariste Nord Projektist, sisekujundaja Kadri Tarbe. Ehitas NCC Ehitus. Rõhku pandi tööruumide mugavusele ja avarusele

  11. Kolhoosikeskus - oma ja võõras = Collective farm centre - familiar and alien / Liina Jänes ; tõlk. Liisi Ojamaa

    Index Scriptorium Estoniae

    Jänes, Liina, 1977-

    2000-01-01

    Eesti kolhoosikeskuste arhitektuurist. Vaadeldakse aastail 1957-1990 ehitatud 24 keskusehoonet. Arhitektid Nikolai Kusmin, Harri Kingo, Toomas Rein, Vilen Künnapu, Ain Padrik, Maara Metsal, Meeli Truu jt. 17 välisvaadet, 3 joon., kaart

  12. Näitlejad ühes mullis, esietendus ukse ees / Hendrik Toompere jr. jr., Liisa Pulk, Mait Joorits ... [jt.] ; intervjueerinud Liisi Seil ; kommenteerinud Helle Leppik

    Index Scriptorium Estoniae

    2010-01-01

    Vestlus Eesti muusika- ja teatriakadeemia lavakunstikooli XXIV lennu tudengitega, kelle lõputöö Tom Stoppardi näidend "Arkaadia" etendub Ugala laval. Lisatud Ugala teatri kirjandustoimetaja arvamus

  13. Tasakaalus tulemuskaardi sage viga on vääralt määratud näitajad / Mait Raava

    Index Scriptorium Estoniae

    Raava, Mait

    2003-01-01

    Tasakaalus tulemuskaart väljendab strateegiliste tulemusnäitajate põhjuslik-tagajärjelisi seoseid, kuid viga tuleb sageli nende tegurite määratlemisel, kirjutab autor. Skeem. Kommenteerib Sven Heil

  14. Smoking reduces circulating CD26hi CD161hi MAIT cells in healthy individuals and patients with multiple sclerosis

    DEFF Research Database (Denmark)

    Ammitzbøll, Cecilie; Börnsen, Lars; Romme Christensen, Jeppe

    2017-01-01

    Upon chronic cigarette smoke exposure, inhaled antigens and irritants cause altered lung immune homeostasis. Circulating immune cells are affected, and smoking is associated with an increased risk of developing various disorders, including multiple sclerosis (MS). This study was conducted...

  15. Hyper-Expression of PD-1 Is Associated with the Levels of Exhausted and Dysfunctional Phenotypes of Circulating CD161++TCR iVα7.2+ Mucosal-Associated Invariant T Cells in Chronic Hepatitis B Virus Infection

    Directory of Open Access Journals (Sweden)

    Yean K. Yong

    2018-03-01

    Full Text Available Mucosal-associated invariant T (MAIT cells, defined as CD161++TCR iVα7.2+ T cells, play an important role in the innate defense against bacterial infections, and their functionality is impaired in chronic viral infections. Here, we investigated the frequency and functional role of MAIT cells in chronic hepatitis B virus (HBV infection. The peripheral CD3+CD161++TCR iVα7.2+ MAIT cells in chronic HBV-infected patients and healthy controls were phenotypically characterized based on CD57, PD-1, TIM-3, and CTLA-4, as well as HLA-DR and CD38 expression. The frequency of MAIT cells was significantly decreased among chronic HBV-infected individuals as compared to controls. Expression of CD57, PD-1, CTLA-4, as well as HLA-DR and CD38 on MAIT cells was significantly elevated in chronic HBV-infected individuals relative to controls. The percentage of T cell receptor (TCR iVα7.2+ CD161+ MAIT cells did not correlate with HBV viral load but inversely with HLA-DR on CD4+ T cells and MAIT cells and with CD57 on CD8+ T cells suggesting that decrease of MAIT cells may not be attributed to direct infection by HBV but driven by HBV-induced chronic immune activation. The percentage and expression levels of PD-1 as well as CTLA-4 on MAIT cells inversely correlated with plasma HBV-DNA levels, which may suggest either a role for MAIT cells in the control of HBV infection or the effect of HBV replication in the liver on MAIT cell phenotype. We report that decrease of TCR iVα7.2+ MAIT cells in the peripheral blood and their functions were seemingly impaired in chronic HBV-infected patients likely because of the increased expression of PD-1.

  16. Armastus on teinud jälle imet / Virve Liivanõmm

    Index Scriptorium Estoniae

    Liivanõmm, Virve

    2011-01-01

    Tallinna Linnamäe vene lütseumist, õpetaja Alla Belenkovast ja tema kirjutatud baltlastest lütseistidele pühendatud monograafiast "Святому братству верен я" ("Pühale vennaskonnale olen truu", kirjastus SE&JS)

  17. Vedurimehed võivad rongiliikluse kolmeks päevaks seisata / Matis Song

    Index Scriptorium Estoniae

    Song, Matis, 1978-

    2004-01-01

    Ametiühing nõuab vedurimeestele 15-protsendilist palgatõusu tagasiulatuvalt selle aasta 1. märtsist, kusjuures peab säilima kehtiv töötasustamise süsteem. Vt. samas: Tiia Truu. Nõudmised ei ole ebaõiglased

  18. Uued kõrghooned Rocca al Mares / Harri Treial

    Index Scriptorium Estoniae

    Treial, Harri

    2003-01-01

    Arhitektuuribüroo Künnapu & Padrik projekteeritud viiest hoonest Vabaõhumuuseumi tee 4 on esimesed valmis.Vabaõhumuuseumi tee 5 kerkib kaks 12-korruselist elamut, mille autoriks on AS Nord Projekt arhitekt Meeli Truu. Sisekujundaja Eerik Olle. 3 ill

  19. Saku Suurhall Rocca al Mares = Saku Suurhall in Rocca al Mare / Inga Raukas

    Index Scriptorium Estoniae

    Raukas, Inga, 1967-

    2001-01-01

    Peaprojekteerija, detailplaneering: Nord Projekt AS. Arhitektid Esa Viitanen (Soome), Andres Kariste, kaastöö: Meeli Truu, Loomet Raudsepp. Sisekujundus: Eero Jürgenson, Maarja Valk-Falk, Tambet Pedak, ARS Interjöörprojekt. Konstruktsioonid: Kaido Kuusiku, Tiit Arumäe, Aive Sau, Jaan Port. Projekteerimise projektijuht Andres Mikker. Projekt 1999-2001, valmis 2001. 9 ill

  20. Mida loodavad poliitikud? / Urmas Lauri

    Index Scriptorium Estoniae

    Lauri, Urmas, 1956-

    1998-01-01

    Vastavad T. Jürgenson, S. Ivanov, A. Rüütel, A. Haug, O. Anton, Pärnoja, M. Kubo, S. Kallas, K. Kilvet, M. Treial, E. Truu. Järgneb 20. jaan. 1998, lk. 2; 22. jaan. 1998, lk. 2; 27. jaan. 1998, lk. 2. Ilmunud ka: Hiiu Leht, 20. jaan. 1998, lk. 3

  1. MR1-restricted mucosal-associated invariant T cells and their activation during infectious diseases

    Directory of Open Access Journals (Sweden)

    Lauren J. Howson

    2015-06-01

    Full Text Available MR1-restricted MAIT cells recognize vitamin B metabolites, which are generated by a broad range of bacteria, from Escherichia coli to Mycobacterium tuberculosis and BCG. MAIT cells have been described as innate sensors of infection as they accumulate early in infected tissues. MAIT cells maintain an activated phenotype throughout the course of infections, secrete inflammatory cytokines and have the potential to directly kill infected cells, playing an important role in shaping the host response. In this review, we will discuss the current knowledge regarding the molecular mechanisms that underline MAIT cells activation in sterile and non-sterile inflammatory conditions.

  2. Muusikalil "Fantoom" ei ole seost Webberi "Ooperifantoomiga" / Andri Maimets

    Index Scriptorium Estoniae

    Maimets, Andri, 1979-

    2007-01-01

    Muusikaliteatri uuest kavandatavast muusikalist "Fantoom" (helilooja Maury Yeston), mille esietendus on 16. novembril Tallinna linnahallis. 20. juunil esietenduvast lavastusest "Tutvumiskuulutus", lavastaja Mait Malmstein

  3. Euroopa Inimõiguste Kohtu (suurkoja) otsus asjas Kononov vs. Läti (kaebus nr 36376/04) / Lauri Mälksoo ; inglise keelest tõlkinud Mait Laaring

    Index Scriptorium Estoniae

    Mälksoo, Lauri, 1975-

    2011-01-01

    17. mail 2010 tegi Euroopa Inimõiguste Kohtu suurkoda otsuse asjas Kononov vs. Läti, otsustades, et Läti ei rikkunud Euroopa inimõiguste ja põhivabaduste kaitse konventsiooni artiklit 7, kui mõistis Vassili Kononovi süüdi Teise maailmasõja ajal Lätis toimepandud sõjakuriteos

  4. Omandi sundvõõrandamise instituut Eesti Vabariigi ja Saksamaa Liitvabariigi õiguskordades : (võrdlev käsitlus) : [bakalaureusetöö] / Mait Laaring ; Tartu Ülikool, õigusteaduskond ; juhendaja: Kalle Merusk

    Index Scriptorium Estoniae

    Laaring, Mait, 1979-

    2003-01-01

    Sundvõõrandamise instituudi ajaloolisest arengust, mõistest, omandigarantii olemusest, sundvõõrandamisest ja sotsialiseerimisest (natsionaliseerimisest), sundvõõrandamise õiguspärasuse eeldustest, tagajärgedest, kohtulikust vaidlustamisest

  5. Neuropathologic, phenotypic and functional analyses of Mucosal Associated Invariant T cells in Multiple Sclerosis.

    Science.gov (United States)

    Salou, Marion; Nicol, Bryan; Garcia, Alexandra; Baron, Daniel; Michel, Laure; Elong-Ngono, Annie; Hulin, Philippe; Nedellec, Steven; Jacq-Foucher, Marylène; Le Frère, Fabienne; Jousset, Natacha; Bourreille, Arnaud; Wiertlewski, Sandrine; Soulillou, Jean-Paul; Brouard, Sophie; Nicot, Arnaud B; Degauque, Nicolas; Laplaud, David-Axel

    2016-05-01

    The involvement of Mucosal Associated Invariant T (MAIT) cells, which are anti-microbial semi-invariant T cells, remains elusive in Multiple Sclerosis (MS). Deciphering the potential involvement of MAIT cells in the MS inflammatory process. By flow cytometry, blood MAIT cells from similar cohorts of MS patients and healthy volunteers (HV) were compared for frequency, phenotype, activation potential after in vitro TCR engagement by bacterial ligands and transmigration abilities through an in vitro model of blood-brain barrier. MS CNS samples were also studied by immunofluorescent staining and quantitative PCR. Blood MAIT cells from relapsing-remitting MS patients and HV presented similar frequency, ex vivo effector phenotype and activation abilities. MAIT cells represented 0.5% of the total infiltrating T cells on 39 MS CNS lesions. This is low as compared to blood frequency (p<0.001), but consistent with their low transmigration rate. Finally, transcriptional over-expression of MR1 - which presents cognate antigens to MAIT cells - and of the activating cytokines IL-18 and IL-23 was evidenced in MS lesions, suggesting that the CNS microenvironment is suited to activate the few infiltrating MAIT cells. Taken together, these data place MAIT cells from MS patients as minor components of the inflammatory pathological process. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Kodalased tähistasid Eesti tantsuõpetuse järjepidevust / Kristiina Garancis

    Index Scriptorium Estoniae

    Garancis, Kristiina, 1969-

    2006-01-01

    1. okt. tähistas oma 30-aastast sünnipäeva ja oma ellukutsuja Mait Agu 55-sünniaastapäeva Tallinna Ülikooli koreograafiaosakond. Sel puhul esitati Estonias Mait Agu tantsulavastus "Kodalased ja kaasaegsed", mille seadis uuesti lavale Märt Agu oma isa loodud koreograafia põhjal

  7. 25 kaadrit sekundis / Liis Auväärt

    Index Scriptorium Estoniae

    Auväärt, Liis

    2009-01-01

    Nukufilmis käib töö filmiga "Lisa Limone & Maroc Orange", režissöör Mait Laas, animaatorid Triin Sarapik-Kivi, Märt Kivi, operaator Ragnar Neljandi, nukumeistrid Heigo Eeriksoo, Taivo Müürsep, Ene Mellow ja Kreeta Käeri. Dekoratsioonimeistrid Mait Erik ja Roman Kuznetsov

  8. Mucosal-Associated Invariant T Cells: New Insights into Antigen Recognition and Activation

    Directory of Open Access Journals (Sweden)

    Xingxing Xiao

    2017-11-01

    Full Text Available Mucosal-associated invariant T (MAIT cells, a novel subpopulation of innate-like T cells that express an invariant T cell receptor (TCRα chain and a diverse TCRβ chain, can recognize a distinct set of small molecules, vitamin B metabolites, derived from some bacteria, fungi but not viruses, in the context of an evolutionarily conserved major histocompatibility complex-related molecule 1 (MR1. This implies that MAIT cells may play unique and important roles in host immunity. Although viral antigens are not recognized by this limited TCR repertoire, MAIT cells are known to be activated in a TCR-independent mechanism during some viral infections, such as hepatitis C virus and influenza virus. In this article, we will review recent works in MAIT cell antigen recognition, activation and the role MAIT cells may play in the process of bacterial and viral infections and pathogenesis of non-infectious diseases.

  9. Mucosal-associated invariant T-cell frequency and function in blood and liver of HCV mono- and HCV/HIV co-infected patients with advanced fibrosis.

    Science.gov (United States)

    Beudeker, Boris J B; van Oord, Gertine W; Arends, Joop E; Schulze Zur Wiesch, Julian; van der Heide, Marieke S; de Knegt, Robert J; Verbon, Annelies; Boonstra, Andre; Claassen, Mark A A

    2018-03-01

    Mucosal-associated invariant T (MAIT) cells are important innate T cells with antimicrobial and immunoregulatory activity, recently found to be depleted in blood of patients with HIV and HCV mono-infections. In this study, we assessed the impact of HIV, HCV and HCV/HIV co-infection on circulating and intrahepatic MAIT-cells and correlations with liver fibrosis. In this cross-sectional study, nine healthy subjects, nine HIV, 20 HCV and 22 HCV/HIV co-infected patients were included. Blood and liver fine needle aspirate biopsies were studied using flowcytometry for CD3 + CD161 + Vα7.2 + MAIT-cell frequency, phenotype and function in HCV mono-infected and HCV/HIV co-infected patients without or with mild fibrosis (Metavir-score F0-F1) or severe fibrosis to cirrhosis (Metavir-score F3-F4). Circulating MAIT-cells were decreased in blood of HCV, HIV and HCV/HIV patients with F0-F1. In HCV/HIV co-infected individuals with severe fibrosis to cirrhosis, the frequency of circulating MAIT-cells was even further depleted, whereas their function was comparable to HCV/HIV co-infected patients with low or absent fibrosis. In contrast, in HCV mono-infected patients, MAIT-cell frequencies were not related to fibrosis severity; however, MAIT-cell function was impaired in mono-infected patients with more fibrosis. More advanced liver fibrosis in HCV or HCV/HIV-infected patients was not reflected by increased accumulation of MAIT-cells in the affected liver. Severe liver fibrosis is associated with dysfunctional MAIT-cells in blood of HCV mono-infected patients, and lower MAIT frequencies in blood of HCV/HIV co-infected patients, without evidence for accumulation in the liver. © 2017 The Authors. Liver International Published by John Wiley & Sons Ltd.

  10. Epigenetic silencing of V(DJ recombination is a major determinant for selective differentiation of mucosal-associated invariant t cells from induced pluripotent stem cells.

    Directory of Open Access Journals (Sweden)

    Yutaka Saito

    Full Text Available Mucosal-associated invariant T cells (MAITs are innate-like T cells that play a pivotal role in the host defense against infectious diseases, and are also implicated in autoimmune diseases, metabolic diseases, and cancer. Recent studies have shown that induced pluripotent stem cells (iPSCs derived from MAITs selectively redifferentiate into MAITs without altering their antigen specificity. Such a selective differentiation is a prerequisite for the use of MAITs in cell therapy and/or regenerative medicine. However, the molecular mechanisms underlying this phenomenon remain unclear. Here, we performed methylome and transcriptome analyses of MAITs during the course of differentiation from iPSCs. Our multi-omics analyses revealed that recombination-activating genes (RAG1 and RAG2 and DNA nucleotidylexotransferase (DNTT were highly methylated with their expression being repressed throughout differentiation. Since these genes are essential for V(DJ recombination of the T cell receptor (TCR locus, this indicates that nascent MAITs are kept from further rearrangement that may alter their antigen specificity. Importantly, we found that the repression of RAGs was assured in two layers: one by the modulation of transcription factors for RAGs, and the other by DNA methylation at the RAG loci. Together, our study provides a possible explanation for the unaltered antigen specificity in the selective differentiation of MAITs from iPSCs.

  11. Eesti edukaimad arhitektid / Karin Paulus

    Index Scriptorium Estoniae

    Paulus, Karin, 1975-

    2008-01-01

    Edukaimad Eesti arhitektuuribürood ärikasumi järgi: 1. Nord Projekt; 2. AB Kalle Rõõmus; 3. RTG Projektbüroo. Arhitektuuribüroo Nord Projekt tegevust tutvustavad Andres Saar ja Meeli Truu. AB Kalle Rõõmus arhitektuuribüroo tähtsamaid töid tutvustab Kalle Rõõmus. RTG Projektbüroo tegevust tutvustab Sander Nurk

  12. Tallinna teekond mereni / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2006-01-01

    Tallinna sadamaala arendamise ajaloost 1990-ndatel aastatel ja 21. sajandi algul. Eraldi projektidest: Kalasadama ümbruse planeering (M. Truu, A. Andres, Nord Projekt, 2000-2006), elamukvartal Logi t. 8, 10 (M. Aunin, M. Melioranski, I. Melioranski, 2005), sadamaala detailplaneeringu eskiis (Tallinna Linnaplaneerimise Amet, 2005), hotell-konverentsikeskus-spaa (Ü. Mark, I. Tiigi, Urban Mark), Admiraliteedi kvartali planeeringu eskiis (Chapman Taylor, London, K-Projekt), Holiday City Tallinn (Evata, Soome), hotell "Merikaru" (M. Schuurman), Lootsi kvartali planeeringu ideeprojekt (Kosmos)

  13. Aasta filmi nominendid

    Index Scriptorium Estoniae

    2008-01-01

    Eesti Filmiajakirjanike Ühing (EFÜ) nimetas 2008.a. filmi auhinna nominendid : Mait Laasi "Aja meistrid", Priit ja Olga Pärna "Elu ilma Gabriella Ferrita", Kadri Kõusaare "Magnus", Priit Pääsukese "Must Peeter", Marko Raadi "Toomiku film"

  14. Vene Kultuurikeskus = The Russian Culture Centre / Margit Mutso

    Index Scriptorium Estoniae

    Mutso, Margit, 1966-

    2010-01-01

    Tallinnas Mere puiestee 5 asuva hoone (arhitekt A. Kuznetsov, 1954) restaureerimisest. Arhitekt Niina Mäger, sisearhitekt Anne Tamverk. Ajaloolane Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud hoonele

  15. Ilmafilosoofia ilma filosoofiata / Jüri Rato

    Index Scriptorium Estoniae

    Rato, Jüri

    2000-01-01

    Arvustus: Hoff, Benjamin. Puhh ja Tao / tlk. Mait Talts. Tln. : Olympia, 1998 ; Hoff, Benjamin. Notsu ja Te / tlk. Paavo Kivine. Tln.: Olympia, 1999 ; Allen, Roger E. ; Allen, Stephen D. Puhh lahendab probleeme / tlk. Paavo Kivine. Tallinn : Olympia, 2000

  16. Kanadas auhinnati Pikkovi "Bermudat"

    Index Scriptorium Estoniae

    pPIK mare 2010

    1999-01-01

    Ottawas 21.-24.okt. toimunud tudengite rahvusvahelisel animafilmide festivalil sai Ülo Pikkovi "Bermuda" festivali direktori auhinna ja žürii eripreemia helikujunduse eest. Osalesid veel eesti filmid "Päevavalgus" (Mait Laas) ja "Kaerajaan" (Mikk Rand)

  17. Akna varastamine : eesti Y-kirjandus / Berk Vaher

    Index Scriptorium Estoniae

    Vaher, Berk, 1975-

    2014-01-01

    Valdur Mikita, Erkki Luuk'i, Kiwa, Kaspari ja kirjanike rühmituse “14 NÜ” (Mait Laas, Paavo Matsin, Marko Mägi, Erkki Kadarik, Marianne Ravi, Maarja Vaino, Trip Jarvis, Johannes Üksi) loomingust

  18. Veider nelik jätkab!

    Index Scriptorium Estoniae

    2008-01-01

    Arvutiga animeeritud USA koguperefilmist "Madagaskar 2" (lavastanud Tim McGrath ja Eric Darnell, eesti keeles loevad teksti Karol Kuntsel, Andero Ermel, Evelin Pang, Argo Aadli, Mait Malmsten, Raivo E. Tamm, Andrus Vaarik, Anne Reemann jt)

  19. Juutide uurimine tõi tunnustuse : eesti teadlaste artikkel jõudis maailma tippajakirja / Marju Himma

    Index Scriptorium Estoniae

    Himma, Marju

    2010-01-01

    Juutide erinevate kogukondade genotüübilistele erinevuste uurimisrühma juhtideks olid Tartu Ülikooli ja Eesti Biokeskuse teadlased Doron M. Behar, Bayazit Yunusbayev, Mait Metspalu ja Richard Villems. Artikkel ilmus teadusajakirjas Nature

  20. Eesti animafilmid võitsid Raumas

    Index Scriptorium Estoniae

    pPIK mare 2010

    1999-01-01

    VI Sinise Mere filmifestivalil Raumas jagasid A-sarjas esikohta Mait Laasi "Päevavalgus" ja Peep Pedmansoni "Just Märried", teiseks jäi Märt Sildvee "Guardian Angel" ja kolmandaks Riho Undi - Hardi Volmeri "Primavera"

  1. Tri gorsti za Tsentralnõi rõnok / Arvi Tapver

    Index Scriptorium Estoniae

    Tapver, Arvi

    1999-01-01

    Mõrvatud endise abilinnapea Mait Metsamaa keskturu erastajatest kaaskond kahlustas tunnistaja sõnul topeltmängu, kui Metsamaa vanale sõbrale ja allilmas kardetavale Meelis Laole erastamisest loobumise eest hüvitist pakkus

  2. Endine turujuht end süüdi ei tunnistanud / Hannes Krause

    Index Scriptorium Estoniae

    Krause, Hannes

    2005-01-01

    Vadim Polishtshuk, keda süüdistatakse koos kahe kaaslasega Mait Metsamaa mõrvaprotsessi peamise tunnistaja ähvardamise ja mõjutamise katses, ei tunnistanud end 19. septembril Tallinna linnakohtus alanud protsessil süüdi

  3. Tallinna Loomeinkubaator = Creative Incubator in Tallinn / Margit Mutso

    Index Scriptorium Estoniae

    Mutso, Margit, 1966-

    2010-01-01

    Tallinnas Veerenni 24C asuva Tallinna Loomeinkubaatori sisekujundusest. Sisearhitektid Raul Tiitus, Tarmo Piirmets (Pink OÜ), graafiline kujundus: Kaarel Vahtramäe (Velvet Studio). Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud sisekujundusele

  4. Vana kaader järel-eesti ajal võimalusi proovimas / Maie Kalda

    Index Scriptorium Estoniae

    Kalda, Maie, 1929-2013

    2001-01-01

    Artikkel põhineb konverentsil "Kohandumise märgid" (20. apr. 2001) peetud ettekandel. Kirjanike elu- ja loominguloost a-tel 1944-1948, lähemalt Mait Metsanurgast, Hugo Raudsepast, Friedebert Tuglasest ja Oskar Lutsust

  5. 9. VI avati Y-galeriis TÜ kunstide osakonna II kursuse maalinäitus "Teised välja!"

    Index Scriptorium Estoniae

    2005-01-01

    Kuraator Anne Parmasto. Näitusel esinevad maalikunsti eriala põhiõppe üliõpilased Marie Kõljalg ja Riho Pärn ning teiste erialade üliõpilased Andrus Raag, Janek Ruus, Eva Lobotkin ja Mait Metspalu

  6. Inimesed ja mesilased / Rein Tootmaa

    Index Scriptorium Estoniae

    Tootmaa, Rein

    2005-01-01

    Nukufilm "Gene+ratio" : stsenarist, kunstnik ja režissöör Mait Laas : konsultant Paavo Matsin : operaatorid Ragnar Neljandi, Raivo Möllits : helilooja Tiit Kikas : Nukufilm OÜ - Icon Film (Saksamaa) 2005

  7. Nukufilm lasi käiku pooletunnise 3D-seiklusfilmi / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2009-01-01

    Stuudios Nukufilm algasid pooletunnise 3D-nukufilmi "Lisa Limone ja Maroc Orange'i tormakas armulugu" võtted. Filmi režissöör on Mait Laas, stsenaristid Kati Kovacs ja Peep Pedmanson, produtsent Arvo Nuut

  8. Taani muinasjutt inimestest ja ehitatud keskkonnast (väikese eesti vimkaga) / Yoko Alender

    Index Scriptorium Estoniae

    Alender, Yoko, 1979-

    2013-01-01

    2013. a. aprillis Taanis toimunud konverentsist "Dedicated to Architecture", mille eesmärk oli arutleda teemal "Arhitektuuriinstitutsioonid kui muutuste mootorid". Eestist osalesid Ülar Mark, Raul Järg, Mait Väljas ja Yoko Alender

  9. "Mina olin siin", võib vastu hambaid saada / Andres Keil

    Index Scriptorium Estoniae

    Keil, Andres, 1974-

    2007-01-01

    Noortefilmi "Mina olin siin" võtetel. Filmi aluseks on Sass Henno romaan "Mina olin siin. Esimene arest", stsenaariumi kirjutas Ilmar Raag, lavastab Rene Vilbre, operaator on Mait Mäekivi, peaosas Rasmus Kaljujärv, produtsendiks Riina Sildos

  10. Esilinastus väge täis "Mina olin siin" / Kutt Kommel

    Index Scriptorium Estoniae

    Kommel, Kutt

    2008-01-01

    Rene Vilbre noortefilm "Mina olin siin", mille aluseks on Sass Henno romaan "Mina olin siin. Esimene arest" : operaator Mait Mäekivi : osades Rasmus Kaljujärv, Hele Kõre jt : Amrion Productions - Helsinki-filmi OY 2008

  11. Mucosal-Associated Invariant T Cell Interactions with Commensal and Pathogenic Bacteria: Potential Role in Antimicrobial Immunity in the Child

    Directory of Open Access Journals (Sweden)

    Liana Ghazarian

    2017-12-01

    Full Text Available Mucosal-associated invariant T (MAIT cells are unconventional CD3+CD161high T lymphocytes that recognize vitamin B2 (riboflavin biosynthesis precursor derivatives presented by the MHC-I related protein, MR1. In humans, their T cell receptor is composed of a Vα7.2-Jα33/20/12 chain, combined with a restricted set of Vβ chains. MAIT cells are very abundant in the liver (up to 40% of resident T cells and in mucosal tissues, such as the lung and gut. In adult peripheral blood, they represent up to 10% of circulating T cells, whereas they are very few in cord blood. This large number of MAIT cells in the adult likely results from their gradual expansion with age following repeated encounters with riboflavin-producing microbes. Upon recognition of MR1 ligands, MAIT cells have the capacity to rapidly eliminate bacterially infected cells through the production of inflammatory cytokines (IFNγ, TNFα, and IL-17 and cytotoxic effector molecules (perforin and granzyme B. Thus, MAIT cells may play a crucial role in antimicrobial defense, in particular at mucosal sites. In addition, MAIT cells have been implicated in diseases of non-microbial etiology, including autoimmunity and other inflammatory diseases. Although their participation in various clinical settings has received increased attention in adults, data in children are scarce. Due to their innate-like characteristics, MAIT cells might be particularly important to control microbial infections in the young age, when long-term protective adaptive immunity is not fully developed. Herein, we review the data showing how MAIT cells may control microbial infections and how they discriminate pathogens from commensals, with a focus on models relevant for childhood infections.

  12. Intra-Hepatic Depletion of Mucosal-Associated Invariant T Cells in Hepatitis C Virus-Induced Liver Inflammation.

    Science.gov (United States)

    Bolte, Fabian J; O'Keefe, Ashley C; Webb, Lauren M; Serti, Elisavet; Rivera, Elenita; Liang, T Jake; Ghany, Marc; Rehermann, Barbara

    2017-11-01

    Chronic hepatitis affects phenotypes of innate and adaptive immune cells. Mucosal-associated invariant T (MAIT) cells are enriched in the liver as compared with the blood, respond to intra-hepatic cytokines, and (via the semi-invariant T-cell receptor) to bacteria translocated from the gut. Little is known about the role of MAIT cells in livers of patients with chronic hepatitis C virus (HCV) infection and their fate after antiviral therapy. We collected blood samples from 42 patients with chronic HCV infection who achieved a sustained virologic response after 12 weeks of treatment with sofosbuvir and velpatasvir. Mononuclear cells were isolated from blood before treatment, at weeks 4 and 12 during treatment, and 24 weeks after the end of treatment. Liver biopsies were collected from 37 of the patients prior to and at week 4 of treatment. Mononuclear cells from 56 blood donors and 10 livers that were not suitable for transplantation were used as controls. Liver samples were assessed histologically for inflammation and fibrosis. Mononuclear cells from liver and blood were studied by flow cytometry and analyzed for responses to cytokine and bacterial stimulation. The frequency of MAIT cells among T cells was significantly lower in blood and liver samples of patients with HCV infection than of controls (median, 1.31% vs 2.32% for blood samples, P = .0048; and median, 4.34% vs 13.40% for liver samples, P = .001). There was an inverse correlation between the frequency of MAIT cells in the liver and histologically determined levels of liver inflammation (r = -.5437, P = .0006) and fibrosis (r = -.5829, P = .0002). MAIT cells from the liver had higher levels of activation and cytotoxicity than MAIT cells from blood (P liver inflammation and MAIT cell activation and cytotoxicity, and increased the MAIT cell frequency among intra-hepatic but not blood T cells. The MAIT cell response to T-cell receptor-mediated stimulation did not change during the 12 weeks of

  13. Synthesis, stabilization, and characterization of the MR1 ligand precursor 5-amino-6-D-ribitylaminouracil (5-A-RU.

    Directory of Open Access Journals (Sweden)

    Kelin Li

    Full Text Available Mucosal-associated invariant T (MAIT cells are an abundant class of innate T cells restricted by the MHC I-related molecule MR1. MAIT cells can recognize bacterially-derived metabolic intermediates from the riboflavin pathway presented by MR1 and are postulated to play a role in innate antibacterial immunity through production of cytokines and direct bacterial killing. MR1 tetramers, typically stabilized by the adduct of 5-amino-6-D-ribitylaminouracil (5-A-RU and methylglyoxal (MeG, are important tools for the study of MAIT cells. A long-standing problem with 5-A-RU is that it is unstable upon storage. Herein we report an efficient synthetic approach to the HCl salt of this ligand, which has improved stability during storage. We also show that synthetic 5-A-RU•HCl produced by this method may be used in protocols for the stimulation of human MAIT cells and production of both human and mouse MR1 tetramers for MAIT cell identification.

  14. STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function

    Science.gov (United States)

    Wilson, Robert P.; Ives, Megan L.; Rao, Geetha; Lau, Anthony; Payne, Kathryn; Kobayashi, Masao; Arkwright, Peter D.; Peake, Jane; Wong, Melanie; Adelstein, Stephen; Smart, Joanne M.; French, Martyn A.; Fulcher, David A.; Picard, Capucine; Bustamante, Jacinta; Boisson-Dupuis, Stephanie; Gray, Paul; Stepensky, Polina; Warnatz, Klaus; Freeman, Alexandra F.; Rossjohn, Jamie; McCluskey, James; Holland, Steven M.; Casanova, Jean-Laurent; Uzel, Gulbu; Ma, Cindy S.

    2015-01-01

    Unconventional T cells such as γδ T cells, natural killer T cells (NKT cells) and mucosal-associated invariant T cells (MAIT cells) are a major component of the immune system; however, the cytokine signaling pathways that control their development and function in humans are unknown. Primary immunodeficiencies caused by single gene mutations provide a unique opportunity to investigate the role of specific molecules in regulating human lymphocyte development and function. We found that individuals with loss-of-function mutations in STAT3 had reduced numbers of peripheral blood MAIT and NKT but not γδ T cells. Analysis of STAT3 mosaic individuals revealed that this effect was cell intrinsic. Surprisingly, the residual STAT3-deficient MAIT cells expressed normal levels of the transcription factor RORγt. Despite this, they displayed a deficiency in secretion of IL-17A and IL-17F, but were able to secrete normal levels of cytokines such as IFNγ and TNF. The deficiency in MAIT and NKT cells in STAT3-deficient patients was mirrored by loss-of-function mutations in IL12RB1 and IL21R, respectively. Thus, these results reveal for the first time the essential role of STAT3 signaling downstream of IL-23R and IL-21R in controlling human MAIT and NKT cell numbers. PMID:25941256

  15. Nirvaana, susla ja internet / Tarmo Teder

    Index Scriptorium Estoniae

    Teder, Tarmo, 1958-

    2000-01-01

    Kolm stuudio Nukufilm uut nukufilmi : "Saamueli Internet" : Stsenarist Andrus Kivirähk : režissöör ja kunstnik Riho Unt; "Teekond Nirvaanasse" : Stsenarist, režissöör ja kunstnik Mait Laas; "Eilne vedur" : režissöörid Mikk Rand ja Kalju Kivi

  16. May anomalous X chromosome methylation be responsible for the ...

    Indian Academy of Sciences (India)

    ria Bonilla-Henao was a research fellow supported by Servicio An- daluz de Salud. We are grateful to Manuel Lacalle for detailed infor- mation about the abortion and to Maite Vargas for the chorionic-villi preparations. References. Avner P. H. and Heard E. 2001 X-chromosome inactivation: count- ing, choice and initiation.

  17. Improviseeritud lugu ja zhanriga mäng / Donald Tomberg

    Index Scriptorium Estoniae

    Tomberg, Donald

    2003-01-01

    Eesti komöödiafilm "Vanad ja kobedad saavad jalad alla" : režissöör Rando Pettai : operaator Mait Mäekivi : näitlejad Henrik Normann, Madis Milling, Robert Gutman jt. : muusika - ansambel Genialistid : Ruut Pictures 2003

  18. Kuidas tuua Eestisse Tiger Woods / Raul Ranne

    Index Scriptorium Estoniae

    Ranne, Raul

    2008-01-01

    Reaalselt arvestades on tõenäosus, et Eestit väisab golfistaar Tiger Woods, muidugi olematu. Teoreetiliselt on see siiski võimalik. Vestlusest Jõelähtme golfiväljakut opereeriv Estonian Golf Country Clubi presidendi Mait Schmidtiga

  19. Eesti disain Berliinis / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2004-01-01

    Näitus "Light. Things" Eesti saatkonnas Berliinis. Osalejad: Tõnis Vellamaa (kuraator), Tarmo Luisk, Mait Summatavet, Kaido Kivi, Pent Talvet, Kristjan Sisa, Andres Labi, Merike Rehepapp, Mehis Tiitsar, Kalli Sein, Gabriel Verilaskja, Annike Laigo, Mare Kelpman, Monika Järg, Eva-Liisa Kriis, Elna Kaasik jt.

  20. Kuus uut Eesti filmi korraga ekraanil / Tarmo Teder

    Index Scriptorium Estoniae

    Teder, Tarmo

    1998-01-01

    21. mail esilinastuvad kinos Sõprus 'Just märried', rezh. Peep Pedmanson; 'Päevavalgus', rezh. Mait Laas; 'Primavera', rezh. Riho Unt ja Hardi Volmer; 'Vares ja hiired', rezh. Priit Tender ja Mikk Rand; 'Bermuda', rezh. Ülo Pikkov; 'Tom ja Fluffy', rezh. Janno Põldma ja Heiki Ernits

  1. Animaalselt ja humaanselt / Karlo Funk

    Index Scriptorium Estoniae

    Funk, Karlo, 1971-

    1998-01-01

    Esilinastus 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer

  2. Aimdusi tsivilisatsioonist / Tarmo Teder

    Index Scriptorium Estoniae

    Teder, Tarmo, 1958-

    1998-01-01

    Esilinastus 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer

  3. Eesti animafilme igale maitsele / Sulev Teinemaa

    Index Scriptorium Estoniae

    Teinemaa, Sulev, 1947-

    1998-01-01

    Esilinastus 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer

  4. Multifilm kui tõsine asi / Marko Mägi

    Index Scriptorium Estoniae

    Mägi, Marko

    1998-01-01

    Esilinastus 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer

  5. Delta Plaza kohvik = The Delta Plaza Café / Margit Mutso

    Index Scriptorium Estoniae

    Mutso, Margit, 1966-

    2010-01-01

    Tallinnas Pärnu mnt. 141 asuva kohviku Delta Plaza sisekujundusest. Sisearhitektid Tiiu Truus ja Marja Viltrop (Stuudio Truus OÜ). Hoone arhitektid Jüri Okas ja Marika Lõoke (AB J. Okas & M. Lõoke). Žürii liikme Mait Summataveti arvamus kohvikust

  6. Tartu kalendritootja investeeris uude tehasesse 100 miljonit / Kadrin Karner

    Index Scriptorium Estoniae

    Karner, Kadrin

    2008-01-01

    Ilmunud ka: Delovõje Vedomosti 24. sept. lk. 5. Tartus avatud Ajasto Diary Groupi kalendritehasesse investeeriti üle 100 miljoni krooni, mille tasuvuspiiriks loeb ettevõte umbes kümme aastat. Vt. samas: Mis on mis: Ajasto Diary Group; Kommenteerivad: Mait Puusepp, Andras Metsa, Kadrin Karner

  7. Vilma lõpetab leivateo / Marko Suurmägi

    Index Scriptorium Estoniae

    Suurmägi, Marko, 1975-

    2008-01-01

    Vilma emafirma Kalev Chocolate Factory juhatuse liikme Mait Nilsoni sõnul jagab Kalev jahutoodete tegemise Jõhvi ja Viljandi ettevõtte vahel nii, et leiba ja saia hakatakse küpsetama Jõhvis ning Viljandisse koondub tortide, kookide ja jahusegude valmistamine. Lisa: Ajalugu

  8. Meie mees Berliinis / Lauri Kärk

    Index Scriptorium Estoniae

    Kärk, Lauri, 1954-

    2005-01-01

    Berliini 55. filmifestivalist : Eesti filmist festivalil (Euroopa noorte režissööride lühifilmidest koosnevat projekti "Kaotatud ja leitud" raamib Mait Laasi nukufilm "Gener+atio"), inglaseDavid MacKenzie mängufilmist "Pelgupaik" ("Asylum")

  9. Lastemuuseum Miia-Milla-Manda = The Miia-Milla-Manda Children's Museum / Margit Mutso

    Index Scriptorium Estoniae

    Mutso, Margit, 1966-

    2010-01-01

    Tallinnas Koidula 21A asuva hoone restaureerimisest, lastemuuseumi sisekujundusest. Kadrioru Lastepargi paviljoni (arhitekt Villem Seidra, 1937) renoveerimisprojekti tegi arhitekt Katrin Etverk, sisearhitektid ja ekspositsiooni kujundus: Maile Grünberg, Eliina Grünberg (Grünberg oü). Ajaloolane Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud hoonele

  10. Sodom i Gomorra v glamurnoi miniatjure / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2006-01-01

    Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions

  11. Absurd on igihaljas / Vaapo Vaher

    Index Scriptorium Estoniae

    Vaher, Vaapo, 1945-

    2006-01-01

    Tutvustus: Camus, Albert. Õnnelik surm / tõlkinud Tanel Lepsoo. Tallinn : Varrak, 2005 ; Metsanurk, Mait. Kreeps / koost. Maire Liivamets. Tallinn : Eesti Raamat, 2005. (Eesti novellivara). Järg: 23. veebr., lk. 27, sisaldab Aivar Kulli kriitikakogu "Kulli pilk" (Ilmamaa, 2005) tutvustust

  12. Eesti teadlaste artikkel juutide põlvnemisest jõudis tippajakirja / Marju Himma

    Index Scriptorium Estoniae

    Himma, Marju

    2010-01-01

    Eesti ja Iisraeli teadlaste rühm uuris juutide geneetilist sarnasust üle maailma. Artikkel avaldati rahvusvahelises teadusajakirjas Nature. Uurimisrühma juhtideks olid Tartu Ülikooli ja Eesti Biokeskuse teadlased Doron M. Behar, Bayazit Yunusbayevi, Mait Metspalu ja Richard Villems

  13. Põlvas näeb Ove Mustingu filmi / Tiia Allas

    Index Scriptorium Estoniae

    Allas, Tiia

    2006-01-01

    8. jaan. linastub Põlva kultuurikeskuses lühimängufilm "Vanameeste paradiis" : stsenaristid Ove Musting (ka idee autor), Urmas Lennuk : režissöör Ove Musting : operaator Mait Mäekivi : helilooja Arian Levin : kunstnik Eva-Marina Gramanovski : näitlejad Tõnu Aav, Aleksander Eelmaa, Tõnu Oja, Ants Ander, Henry Kõrvits : Downtown Pictures 2005

  14. Ilma tahtmata ja teadmata paradiisi ehk Arhetüüp eesti moodi / Rein Tootma

    Index Scriptorium Estoniae

    Tootma, Rein

    2006-01-01

    Lühimängufilm "Vanameeste paradiis" : stsenaristid Ove Musting (ka idee autor), Urmas Lennuk : režissöör Ove Musting : operaator Mait Mäekivi : helilooja Arian Levin : kunstnik Eva-Marina Gramanovski : näitlejad Tõnu Aav, Aleksander Eelmaa, Tõnu Oja, Ants Ander, Henry Kõrvits : Downtown Pictures 2005

  15. Eesti osaleb suurejoonelises filmiprojektis

    Index Scriptorium Estoniae

    pPIK mare 2010

    2004-01-01

    Filmiprojekt tööpealkirjaga "Generation", mis on plaanitud täispikaks mängufilmilaadseks filmiks. Tegemisse on kaasatud kuus noort režissööri Ida-Euroopast. Eestit esindab animafilmide režissöör Mait Laas, kes teeb valmivale filmile raamjutustuse

  16. Nick Park pani Wallace'ile ja Gromitile libaküüliku needuse / Mart Rummo

    Index Scriptorium Estoniae

    Rummo, Mart

    2005-01-01

    Uus animafilm "Wallace ja Gromit : Libaküüliku needus" ("Wallace & Gromit : The Curse of the Were-Rabbit") : režissöör Nick Park : Suurbritannia 2005. Selle loojast ja tema loometeest. Lisatud : Nick Park (filmograafia, auhindu), "Teised Nick Parkist" (Lauri Kaare, Mait Laas, Riho Unt)

  17. Sada aastat kutselist müüdiloometööstust / Madis Kolk

    Index Scriptorium Estoniae

    Kolk, Madis

    2006-01-01

    Müüdiloomest rahvusliku dramaturgia näol - A. Kitzbergi "Tuulte pöörises", Mait Metsanurga "Päikese tõusul", A. Kivirähki "Eesti matus", "Adolf Rühka lühikene elu", Teatriparadiis", "Sürrealistid"

  18. Wow! Tallinn! / Jaak Rand

    Index Scriptorium Estoniae

    Rand, Jaak

    2006-01-01

    Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions. Lisatud Jüri Sillarti filmograafia lk. 83

  19. 432 püksipaari Riia kongresside palee fassaadil / Lauri Kärk

    Index Scriptorium Estoniae

    Kärk, Lauri, 1954-

    2000-01-01

    Filmifestivalil "Arsenals" sai parima režissööri kujukese Mait Laas nukufilmi "Teekond Nirvaanasse" eest, teise koha preemia Valentin Kuigi mängufilm "Lurjus" ja Riho Undi nukufilm "Saamuel internetis". Peaauhinna andis loos shoti naisrežissööri Lynne Ramsay mängufilmile "Rotipüüdja" ("Ratcatcher")

  20. Chaque chose est une prison / Jaan J. Leppik

    Index Scriptorium Estoniae

    Leppik, Jaan J.

    2007-01-01

    Rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov : Eesti - Island - Saksamaa - Soome - Sloveenia, 2005

  1. Aasta esimene Tuna / Vello Helk

    Index Scriptorium Estoniae

    Helk, Vello, 1923-2014

    2009-01-01

    ajakiri Tuna, 2009, nr. 1 sisust: Mait Kõivu Trooja sõja aineline essee, Tiina Kala Saare-Lääne piiskopi Johannes Kiveli ametissepühitsemine 1515. aastal, Jaan Rossi artikkel teadlaste panusest muusikasse, Riho Saardi Eesti Kirikute Nõukogu sünnilugu, Vello Salo 1924. aasta 1. detsembri lööksalkade juhtkonnast

  2. Baltika büroo = The Baltika Offices / Margit Mutso

    Index Scriptorium Estoniae

    Mutso, Margit, 1966-

    2010-01-01

    Tallinnas Veerenni 24 asuvast Baltika büroost. Arhitektuur, bürooruumide kujundus: AB Studio 3, Kolm Pluss Üks Arhitektid. Žürii liige Mait Summatavet žürii hinnangust EK arhitektuuri sihtkapitali 2009. a. sisearhitektuuri preemia pälvinud bürooruumidele

  3. Karmid mängud / Kristel Raesaar

    Index Scriptorium Estoniae

    Raesaar, Kristel

    2000-01-01

    Tüli puiduärimehega maksis Hansapangale üle 100 miljoni. Lisa: ühed faktid, mitu tõlgendust - Hansapanga kreedidirektor Aivar Rehe, ECT tegevjuhi Arvi Schilfi ja laenu varjamises süüdistatud Hansapanga endise väliskaubanduse finantseerimise osak. juhataja Mait Kolditsa nägemus ECT laenuraha kadumisega seotud sündmustest

  4. Loomad räägivad sel korral eesti keeles / Jaanus Noormets

    Index Scriptorium Estoniae

    Noormets, Jaanus

    2008-01-01

    Arvutiga animeeritud USA koguperefilmist "Madagaskar 2" (Madagascar: Escape 2 Africa), mis jõuab Eesti kinodesse erinevalt filmisarja esimesest osast eesti keelde dubleerituna (loomtegelastele on oma hääle laenanud Karol Kuntsel, Andero Ermel, Evelin Pang, Mait Malmsten, Raivo E. Tamm, Andrus Vaarik jt)

  5. Lavaka lõpetajate pink on pikk / Tiiu Laks

    Index Scriptorium Estoniae

    Laks, Tiiu, 1984-

    2009-01-01

    Kevadel lavakunstikooli lõpetavate tudengite lavastusest "Pikk pink" , mis koosneb kuuest lühiloost - Mait Jooritsa "Kantani padi", Kristjan Üksküla "Jääger" ja "Albioni tütar", Roland Laosi "Genees ja katastroof", Hendrik Toompere jun. jun. "Karupoeg Puhh" ja Kerttu Moppeli " Leib!". Etendused toimuvad Hobuveskis

  6. Ära kosi Pikka: Pikk läheb pingile magama / Meelis Oidsalu

    Index Scriptorium Estoniae

    Oidsalu, Meelis, 1978-

    2010-01-01

    Kevadel lavakunstikooli lõpetavate tudengite lavastusest "Pikk pink" , mis koosneb kuuest lühiloost - Mait Jooritsa "Kantani padi", Kristjan Üksküla "Jääger" ja "Albioni tütar", Roland Laosi "Genees ja katastroof", Hendrik Toompere jun. "Karupoeg Puhh" ja Kerttu Moppeli " Leib!". Esietendus 23. nov. Hobuveskis

  7. Eesti animafilmid Ottawas / M. L.

    Index Scriptorium Estoniae

    M. L.

    2006-01-01

    Ottawa rahvusvahelisel animafilmifestivalil 20.-24. sept. võistlesid Eesti poolt Mati Küti "Une instituut" ja "Vulcain.Cricet", Priit Tenderi "Sõnum naabritele", Ülo Pikkovi "Elu maitse" ja Mait Laasi "Generatsioon". Eesti auhindu ei saanud. Peaauhind täispika animatsiooni eest läks inglasele Phil Mulloy'le filmi "Christied" eest

  8. Nõmme Lunastaja kirik = The Saviour's Lutheran Church in Nõmme / Margit Mutso

    Index Scriptorium Estoniae

    Mutso, Margit, 1966-

    2010-01-01

    Tallinnas Õie 10 asuva kirikuhoone (arhitekt Robert Natus, 1932) restaureerimisest. Arhitekt Fredi-Armand Tomps, sisearhitekt Anne Koppel, ehitusjärelevalve: Rein Joller, ajaloolane Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang EK arhitektuuri sihtkapitali 2009. a. restaureerimispreemia pälvinud hoonele

  9. Toompea komandandimaja = The Commandant's House in Toompea / Margit Mutso

    Index Scriptorium Estoniae

    Mutso, Margit, 1966-

    2010-01-01

    Tallinnas Toompea 1 asuva hoone restaureerimisest. Arhitekt Raul Vaiksoo, kaasautor Kristo Vaiksoo (Raul Vaiksoo Arhitektuuribüroo), sisearhitektid Priit Põldme, Rita Rahu (SAB Joonprojekt), Raul Vaiksoo, ajaloolased Raul Vaiksoo, Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud hoonele

  10. Keskmiselt kobe vaatamine / Küllike Rooväli

    Index Scriptorium Estoniae

    Rooväli, Küllike, 1969-

    2004-01-01

    Eesti komöödiafilm "Vanad ja kobedad saavad jalad alla" : režissöör Rando Pettai : operaator Mait Mäekivi : näitlejad Henrik Normann, Madis Milling, Robert Gutman jt. : muusika - ansambel Genialistid : Ruut Pictures 2003

  11. Superorgaaniline animatsioon / Jan Kaus

    Index Scriptorium Estoniae

    Kaus, Jan, 1971-

    2006-01-01

    Eesti uuemast animafilmist. Põhjalikumalt on käsitletud 2005.a. eesti animatsioonikunsti tippteosena Mait Laasi filmi "Generatio". Lisatud lühiandmed M. Laasi kohta, samuti kuue riigi koostööfilmi "Kaotatud ja leitud" kohta, mille lühifilmid seob tervikuks "Generatio"

  12. Nukufilmi erootika / Jaan Ruus

    Index Scriptorium Estoniae

    Ruus, Jaan, 1938-2017

    2005-01-01

    Kaks eesti nukufilmi - "Laud" : autorid Jelena Girlin ning Mari-Liis Bassovskaja : operaator ja kaasrežissöör Urmas Jõemees : helilooja Malle Maltis : Nukufilm OÜ 2004 ja "Generatio" : stsenarist, kunstnik ja režissöör Mait Laas : konsultant Paavo Matsin : operaatorid Ragnar Neljandi, Raivo Möllits : helilooja Tiit Kikas : Nukufilm OÜ - Icon Film (Saksamaa) 2005

  13. Valijad ootavad rektorilt kõhklematuid otsuseid / Andres Koppel, Einar Orgmets, Jaak Jaaniste, Margus Arak ; küsitlenud Kerttu Jänese

    Index Scriptorium Estoniae

    2007-01-01

    Küsimusele, kuidas jäite rahule valimistulemustega ja millised on esimesed sammud, mida uuelt rektorilt Mait Klaassenilt ootate, vastavad Eesti Maaülikooli valimiskogu liikmed teadusprorektor Andres Koppel, veterinaarmeditsiini instituudi õppedirektor Einar Orgmets, tehnikainstituudi dotsent Jaak Jaaniste ja valimiskomisjoni liige Margus Arak

  14. Kirjandus ja vabamüürlus / Paavo Matsin

    Index Scriptorium Estoniae

    Matsin, Paavo, 1970-

    2009-01-01

    Loetletakse vabamüürlastest kirjanikke (pikemalt Jules Verne'ist, Gustav Meyrinkist, Rudyard Kiplingist ja Mait Metsanurgast) ning vabamüürlikke tegelasi või motiive kasutanud kirjanikke (Lev Tolstoi, Fjodor Dostojevski, Mihhail Bulgakov, Edgar Allan Poe)

  15. Poolsajandi õnnesoovid Jaak Aaviksoole / Ain Heinaru, Jaak Kangilaski, Tõnu Lehtsaar...[jt.

    Index Scriptorium Estoniae

    2004-01-01

    Mõtteid Tartu Ülikooli rektorist tema 50. sünnipäeva puhul : Ain Heinaru, Jaak Kangilaski, Tõnu Lehtsaar, Indrek Reimand, Toomas Kiho, Leelo Kriisa, Peeter Olesk, Risto Tammelo, Birute Klaas, Peeter Saari, Andrus Ansip, Mait Klaassen, Marika Kullamaa, Kaupo Bend

  16. Maie, Valdur ja Silvi teevad Eesti filmiajalugu / Neeme Korv

    Index Scriptorium Estoniae

    Korv, Neeme, 1974-

    2002-01-01

    Alustati täispika rahvakomöödia "Vanad ja kobedad saavad jalad alla" või "Seiklusjutte maalt" võtteid, mis tehakse täies mahus digitaalkaameraga. Režissöör on Rando Pettai, operaator Mait Mäekivi, stsenarist Peep Pedmanson

  17. Sinikael jätab jälgi / Tristan Priimägi

    Index Scriptorium Estoniae

    Priimägi, Tristan, 1976-

    2002-01-01

    Mängufilm "Agent Sinikael" : stsenaristid Marko Raat ja Andres Maimik : režissöör Marko Raat : operaator Arko Okk : helilooja Janek Murd : kunstnikud Margus Tammik ja Jaana Jüris : nimiosas Mait Malmsten : produtsendid Peeter Urbla ja Veiko Õunapuu : Exitfilm ja Suhkur Film, 2002. Lisatud Marko Raati filmograafia lk. 103

  18. Võigas ja seletamatu tsirkus : kaasaja ja alateadvuse pained "Agent Sinikaelas" / Sven Vabar

    Index Scriptorium Estoniae

    Vabar, Sven

    2002-01-01

    Mängufilm "Agent Sinikael" : stsenaristid Marko Raat ja Andres Maimik : režissöör Marko Raat : operaator Arko Okk : helilooja Janek Murd : kunstnikud Margus Tammik ja Jaana Jüris : nimiosas Mait Malmsten : produtsendid Peeter Urbla ja Veiko Õunapuu : Exitfilm ja Suhkur Film, 2002

  19. Veerandsada aastat punast teatrimaja / Rannar Raba

    Index Scriptorium Estoniae

    Raba, Rannar, 1979-

    2006-01-01

    Viljandi uue teatrimaja sünnilugu. Arhitektuurivõistluse võitsid Irina Raud ja Inga Ring (nüüd Orav). Sisekujunduse tegi Mait Summatavet. Ehitas Viljandi MEK. Avati 29. detsembril 1981. Meenutavad Ülo Stöör ja Irina Raud

  20. Näitleja Anti Reinthal : "Kui sa just surnud ei ole, siis mängid lõpuni!" / Katrin Rohtla

    Index Scriptorium Estoniae

    Rohtla, Katrin, 1966-

    2007-01-01

    Viinistu kunstimuuseumis etenduva Eesti Draamateatri suvelavastuse "Sürrealistid" 30. juuni etenduses vigastas näitleja raskelt oma reielihast kuid mängis lõpuni. Lisaks Mait Malmsteni kommentaar "Malmsten : "Esimene vaatus mängiti fantaasia abil" ja vaataja arvamus : "Publiku pettis ära"

  1. Sõpruses esilinastub Eesti-Islandi tantsufilm

    Index Scriptorium Estoniae

    2005-01-01

    10. novembril esilinastub rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov. Filmi võtted toimusid Tartu vanglas

  2. Rohkem kui lihtsalt tantsufilm / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2005-01-01

    Rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov : Eesti - Island 2005

  3. Vanglamüüride vahel võeti üles tantsufilmi / Villu Päärt

    Index Scriptorium Estoniae

    Päärt, Villu, 1972-

    2005-01-01

    ETV-l valmib koos EFS-i ja Estinfilmiga kultuurikanali ARTE tellimusel tantsufilm "Teine" : režissöör Rene Vilbre : stsenarist Teet Kask : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov. Filmi võtetest Tartu vanglas

  4. Tantsufilm "Teine" ETV-s

    Index Scriptorium Estoniae

    2005-01-01

    Täna on ETV-s rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov. Filmi võtted toimusid Tartu vanglas

  5. Vanglarahvas tantsib Euroopasse / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2005-01-01

    Rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov. Filmi võtted toimusid Tartu vanglas

  6. Võtme ja riiviga tantsufilm / Kristiina Garancis

    Index Scriptorium Estoniae

    Garancis, Kristiina, 1969-

    2005-01-01

    Rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov : Eesti - Island 2005

  7. Saagu valgus / Karin Tarto

    Index Scriptorium Estoniae

    Paulus, Karin, 1975-

    1998-01-01

    Eesti valgustikujundajatest ja valgustitest. Kas eesti disaineritel on õnnestunud leida oma nišš lambiletil. Tootjatest : OÜ "Raunto", AS "Titanus" (disaineriks Eestis elav rootslane Renni Par)-, Norrast pärineva kontserni "Glamox" tehasest Keilas, "Estoplastist" (disainerid Martin Pärn, Raido Laasing), AS "Steel Line". Valgustikujundajatest Tarmo Luisust, Aleksander Jakovlevist, Raivo Pristolist, Mait Summatavetist, Tõnis Vellamast

  8. Paariselamu Luccas = Duplex House in Lucca / Indrek Allmann

    Index Scriptorium Estoniae

    Allmann, Indrek, 1972-

    2001-01-01

    Projekteerija: Arhitektuuribüroo Kolde Grupp. Arhitekt Indrek Allmann, konstruktorid Andres Läänesaar, Aldur Parts, Valdo Jaanisoo, Mait Mets. Hoone asub panga ülemise tasandi kõrgusel õhus, pangapealsega on ühendatud terrassi abil, ligipääs alumisel tasandil. Projekt 1999, valmis 2001. 5 ill.: põhiplaan, vaated

  9. Väikeelamine suureks - normaalpere konteinersüsteemis = Small living space made bigger - container system for a typical family

    Index Scriptorium Estoniae

    2009-01-01

    Tutvustatakse Tallinna Tehnikakõrgkooli Arhitektuuri Instituudi arhitektuuri eriala üliõpilaste töid teemal "Väikeelamine suureks - normaalpere konteinersüsteemis". Idee: rahuldada ühesuuruste "konteinerite" baasil ehitatud torn- või ridamajadega väikekorterite nõudlust. Juhendaja: sisearhitekt Mait Summatavet (lk. 60 andmeid M. Summataveti elu ja loomingu kohta)

  10. Jõgeva bussijaam sai liimpuidu kasutamise eripreemia

    Index Scriptorium Estoniae

    2009-01-01

    Konkursil Eesti Parim Puitehitis 2009 sai liimpuidu kasutamise eripreemia Jõgeva bussijaam, arhitektid Andres Lunge ja Mait Lauri firmast Lunge & Co OÜst. Peapreemia pälvis suvila Jõelähtmel, arhitekt Sten Ader büroost SKAD Arhitektid. Loetletud ka teisi auhinnalistele kohtadele tulnud töid

  11. "Riigikogu hoone 90" = "Estonian parliament building 90" / Janno Roos, Andres Labi

    Index Scriptorium Estoniae

    Roos, Janno, 1976-

    2013-01-01

    Eesti Sisearhitektide Liidu 2012. aasta näituse kujunduse preemia pälvinud näitusest (Lossiplats 1A). Kujunduse autorid Janno Roos ja Andres Labi (Ruumilabor). Kuraator Mait Väljas. Graafiline disain: Identity. Sisearhitekti ja ESLi aastapreemiate žürii liikme Mari Kurismaa ning arhitektuuriajaloolase Leele Välja arvamused

  12. The Utility of the Metacognitive Awareness Inventory for Teachers among In-Service Teachers

    Science.gov (United States)

    Kallio, Heli; Virta, Kalle; Kallio, Manne; Virta, Arja; Hjardemaal, Finn Rudolf; Sandven, Jostein

    2017-01-01

    The purpose of the present study is to explore the utility of the compressed version of the Metacognitive Awareness Inventory for Teachers (MAIT-18) among in-service teachers. Knowledge of teachers' awareness of metacognition is required to support students' self-regulation, with the aim of establishing modern learning methods and life-long…

  13. Circulating activated innate lymphoid cells and mucosal-associated invariant T cells are associated with airflow limitation in patients with asthma

    Directory of Open Access Journals (Sweden)

    Ayako Ishimori

    2017-04-01

    Conclusions: For the first time, our data showed that activated NK cells, ILC1s, ILC2s, ILC3s, and MAIT cells were positively correlated with each other and may be associated with airflow limitation in patients with asthma.

  14. Balkanist Baltimaadeni. Mis nägu on postkommunistliku Euroopa film? / Annika Koppel

    Index Scriptorium Estoniae

    Koppel, Annika

    2005-01-01

    Muljeid Wiesbadenis toimunud festivalilt "goEast" (Festival of Central and Eastern European Film). Pikemalt kuue noore režissööri rahvusvahelisest filmiprojektist "Kaotatud ja leitud", mille sidus kokku Mait Laasi nukufilm "Generatio". Lisatud auhinnatud filmide nimekiri ning nimekiri "Eesti filmid Wiesbadenis"

  15. Kogunevad kõrghariduse võrgu korrastamise komisjonid / Merike Määrits

    Index Scriptorium Estoniae

    Määrits, Merike

    2000-01-01

    Moodustati Tallinna ja Tartu ekspertkomisjonid, et kujundada seisukohad kõrgkoolide võrgu võimalikeks institutsionaalseteks muutusteks. Komisjoni kuuluvad : Jüri Allik, Arvi Altmäe, Mait Arviso, Talis Bachmann, Leif Kalev, Marge Kõiva, Mikko Lagerspetz, Ott Lumi, Mart Susi, Jüri Tanner, Rein Vaikmäe

  16. Algasid Henno "Mina olin siin" järgi tehtava filmi võtted

    Index Scriptorium Estoniae

    2007-01-01

    Eile algasid noortefilmi "Mina olin siin" võtted. Filmi aluseks on Sass Henno romaan "Mina olin siin. Esimene arest", stsenaariumi kirjutas Ilmar Raag, lavastab Rene Vilbre, operaator on Mait Mäekivi, peaosas Rasmus Kaljujärv, produtsendiks Riina Sildos

  17. Unique and Common Features of Innate-Like Human Vδ2+ γδT Cells and Mucosal-Associated Invariant T Cells

    Directory of Open Access Journals (Sweden)

    Nicholas M. Provine

    2018-04-01

    Full Text Available Mucosal-associated invariant T (MAIT cells are innate-like T cells abundant in humans that can be activated in a TCR-independent manner by inflammatory and antiviral cytokines. In humans, the capacity for TCR-independent activation is functionally linked to a transcriptional program that can be identified by the expression of the C-type lectin receptor, CD161. In addition to MAIT cells, it has been demonstrated that a subset of γδT cells expresses CD161 and can be activated by TCR-independent cytokine stimulation. In this study, we sought to clarify the nature of cytokine-responsive human γδT cells. We could link CD161 expression on Vδ2+ versus Vδ1+ γδT cells to the observation that Vδ2+ γδT cells, but not Vδ1+ γδT cells, robustly produced IFN-γ upon stimulation with a variety of cytokine combinations. Interestingly, both CD161+ and CD161− Vδ2+ γδT cells responded to these stimuli, with increased functionality within the CD161+ subset. This innate-like responsiveness corresponded to high expression of PLZF and IL-18Rα, analogous to MAIT cells. Vδ2+ γδT cells in human duodenum and liver maintained a CD161+ IL-18Rα+ phenotype and produced IFN-γ in response to IL-12 and IL-18 stimulation. In contrast to MAIT cells, we could not detect IL-17A production but observed higher steady-state expression of Granzyme B by Vδ2+ γδT cells. Finally, we investigated the frequency and functionality of γδT cells in the context of chronic hepatitis C virus infection, as MAIT cells are reduced in frequency in this disease. By contrast, Vδ2+ γδT cells were maintained in frequency and displayed unimpaired IFN-γ production in response to cytokine stimulation. In sum, human Vδ2+ γδT cells are a functionally distinct population of cytokine-responsive innate-like T cells that is abundant in blood and tissues with similarities to human MAIT cells.

  18. La persona feliz : personalidad, bienestar psicológico subjetivo y variables predictoras

    OpenAIRE

    Martín Martín, Carla

    2015-01-01

    El propósito de este trabajo es realizar una réplica del estudio de Maite Garaigordobil, Jone Aliri e Iraide Fontaneda, titulado “Bienestar Psicológico Subjetivo: diferencias de sexo, relaciones con dimensiones de personalidad y variables predictoras”(2009). En dicho trabajo, analizan diferentes variables en relación al bienestar psicológico subjetivo, exploran las relaciones del bienestar psicológico y el material con las dime...

  19. Eesti televisioon tähistab üleilmset tantsupäeva erikavaga / Andri Maimets

    Index Scriptorium Estoniae

    Maimets, Andri, 1979-

    2006-01-01

    Rahvusvahelisel tantsupäeval 29. aprillil on ETV eetris kolm tantsufilmi : rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov ; Mozarti muusikale loodud "Suur missa" : koreograaf Uwe Scholz : Austria - Saksamaa ja inglise tantsufilm "Elu hind" : koreograaf Lloyd Newson

  20. Vabaduse väljak = The first design stage of Freedom Square / Margit Mutso

    Index Scriptorium Estoniae

    Mutso, Margit, 1966-

    2010-01-01

    Tallinna Vabaduse väljakust, mis pälvis Eesti Kultuurkapitali 2009. aasta aastapreemia uue kvaliteedi eest Eesti linnaehituses ja avaliku ruumi loomisel. Arhitektid: Andres Alver, Veljo Kaasik, Tiit Trummal, kaasautorid Indrek Rünkla, Tarmo Laht, Sven Koppel, Ulla Saar, Toomas Tammis (Alver Arhitektid OÜ). Ajaloolane Rein Zobel. Žürii liikmete Kalle Komissarovi ja Mait Summataveti hinnang väljakule

  1. Suur esilinastamine

    Index Scriptorium Estoniae

    1998-01-01

    21.5. esilinastuvad kinos "Sõprus" 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer. Aut. : M.R

  2. Esilinastuvad eesti animafilmid

    Index Scriptorium Estoniae

    1998-01-01

    21.5. esilinastuvad kinos "Sõprus" 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer

  3. Animatsiooni vastu ei saa ükski / Mikk Rand

    Index Scriptorium Estoniae

    Rand, Mikk, 1970-

    1998-01-01

    21.5. esilinastuvad kinos "Sõprus" 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer

  4. Kuus uut Eesti filmi korraga ekraanil / Tarmo Teder

    Index Scriptorium Estoniae

    Teder, Tarmo, 1958-

    1998-01-01

    21.5. esilinastuvad kinos "Sõprus" 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer

  5. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    TIMP2 gene polymorphisms are associated with hypertension in patients with myocardial infarction. José Manuel Rodríguez-Pérez Nancy Martínez-Rodríguez Gilberto Vargas-Alarcón Maite Vallejo Irma Eloisa Monroy-Muñoz Carlos Posadas-Romero Eric Kimura-Hayama Teresa Juárez-Cedillo José Manuel Fragoso ...

  6. Karl Menningu (ja iseenese) päästmiseks / Ants Hein

    Index Scriptorium Estoniae

    Hein, Ants, 1952-

    2008-01-01

    Vastuseks Karin Hallas-Murula arvustusele "Maja, mis on sümbol" (Sirp, 2007, 5. X, lk. 13) ja Mait Väljase arvustusele "Iseolemise algus arhitektuuris" (Maja, 2008, nr. 1, lk. 86-87) oma 2007. a. ilmunud raamatust "Maja kui sümbol : Eesti Üliõpilaste Seltsi hoone Tartus" kohta. Georg Hellati ja Karl Menningu osalusest EÜS-i hoone sünniloos. Frank Lloyd Wrightist kui võimalikust eeskujuandjast

  7. Short outlines of books by Estonian authors : [annotations] / Rutt Hinrikus, Janika Kronberg

    Index Scriptorium Estoniae

    Hinrikus, Rutt, 1946-

    1999-01-01

    Ehin, Andres. Seljatas sada meest; Ilmet, Peep. Tuuldunud luule; Kaplinski, Jaan. Öölinnud. Öömõtted; Kender, Kaur. Iseseisvuspäev; Kesküla, Kalev. Vabariigi laulud; Luik, Viivi. Maa taevas; Nõu, Helga. Hundi silmas; Raun, Mait. Wake up; Remsu, Olev. Haapsalu tragöödia; Sauter, Peeter. Kogu moos; Undusk, Jaan. Maagiline müstiline keel; Vint, Toomas. Kunstnikuromaan

  8. Kodumaine multifilm õilmitseb / Mart Rummo

    Index Scriptorium Estoniae

    Rummo, Mart

    2001-01-01

    Tähistamaks eesti animafilmi 70. aastapäeva näidatakse täna Kinomajas kuut uut multifilmi : 13-osaline lamenukkfilm "Tulelaeva kulid" (režissöör Mait Laas), Ülo Pikkovi kaks joonisfilmi "Superlove" ja "Peata ratsanik", Priit Tenderi joonisfilm "Mont Blanc", Kaspar Jancise joonisfilm "Romanss" ja Janno Põldma - Heiki Ernitsa laste joonisfilmiseriaali "Lepatriinude jõulud" 5-min. trailer

  9. Tjoplõi dozhd v zale suda / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2006-01-01

    Mängufilm "Meeletu" : stsenaristid Jaan Tätte, Elmo Nüganen : režissöör Elmo Nüganen : operaator Mait Mäekivi : produtsent Kristian Taska : helilooja Jaak Jürisson : peaosas Rain Simmul : Taska Film - Eesti Televisioon 2006. Võrreldakse näidendi lavastust ja filmi. Arvustuses on Jüri osatäitjaks ekslikult nimetatud lavastuse osatäitjat Allan Noormetsa ( tegelikult Aivar Tommingas)

  10. Barbarid, plastiliinijänes, Miriam ja Frank Muller / Annika Koppel

    Index Scriptorium Estoniae

    Koppel, Annika

    2003-01-01

    Nukufilm näitab 4 uut filmi : "Barbarid" (stsenaristid Andrus Kivirähk ja Hardi Volmer, režissöör H. Volmer), "Porgand" (stsenarist Peep Pedmanson, režissöör Pärtel Tall), "Miriami jõulupäkapikk" (stsenaristid Leelo Tungal ja Peep Pedmanson, režissöör Mait Laas), "Kuuvaatleja" (reklaamitreiler Frank Mulleri kellafirmale ; stsenarist, režissöör, kunstnik Mati Kütt)

  11. Human lung epithelial cells contain Mycobacterium tuberculosis in a late endosomal vacuole and are efficiently recognized by CD8⁺ T cells.

    Directory of Open Access Journals (Sweden)

    Melanie J Harriff

    Full Text Available Mycobacterium tuberculosis (Mtb is transmitted via inhalation of aerosolized particles. While alveolar macrophages are thought to play a central role in the acquisition and control of this infection, Mtb also has ample opportunity to interact with the airway epithelium. In this regard, we have recently shown that the upper airways are enriched with a population of non-classical, MR1-restricted, Mtb-reactive CD8⁺ T cells (MAIT cells. Additionally, we have demonstrated that Mtb-infected epithelial cells lining the upper airways are capable of stimulating IFNγ production by MAIT cells. In this study, we demonstrate that airway epithelial cells efficiently stimulate IFNγ release by MAIT cells as well as HLA-B45 and HLA-E restricted T cell clones. Characterization of the intracellular localization of Mtb in epithelial cells indicates that the vacuole occupied by Mtb in epithelial cells is distinct from DC in that it acquires Rab7 molecules and does not retain markers of early endosomes such as Rab5. The Mtb vacuole is also heterogeneous as there is a varying degree of association with Lamp1 and HLA-I. Although the Mtb vacuole shares markers associated with the late endosome, it does not acidify, and the bacteria are able to replicate within the cell. This work demonstrates that Mtb infected lung epithelial cells are surprisingly efficient at stimulating IFNγ release by CD8⁺ T cells.

  12. Mucosal-associated invariant T cell is a potential marker to distinguish fibromyalgia syndrome from arthritis.

    Science.gov (United States)

    Sugimoto, Chie; Konno, Takahiko; Wakao, Rika; Fujita, Hiroko; Fujita, Hiroyoshi; Wakao, Hiroshi

    2015-01-01

    Fibromyalgia (FM) is defined as a widely distributed pain. While many rheumatologists and pain physicians have considered it to be a pain disorder, psychiatry, psychology, and general medicine have deemed it to be a syndrome (FMS) or psychosomatic disorder. The lack of concrete structural and/or pathological evidence has made patients suffer prejudice that FMS is a medically unexplained symptom, implying inauthenticity. Furthermore, FMS often exhibits comorbidity with rheumatoid arthritis (RA) or spondyloarthritis (SpA), both of which show similar indications. In this study, disease specific biomarkers were sought in blood samples from patients to facilitate objective diagnoses of FMS, and distinguish it from RA and SpA. Peripheral blood mononuclear cells (PBMCs) from patients and healthy donors (HD) were subjected to multicolor flow cytometric analysis. The percentage of mucosal-associated invariant T (MAIT) cells in PBMCs and the mean fluorescent intensity (MFI) of cell surface antigen expression in MAIT cells were analyzed. There was a decrease in the MAIT cell population in FMS, RA, and SpA compared with HD. Among the cell surface antigens in MAIT cells, three chemokine receptors, CCR4, CCR7, and CXCR1, a natural killer (NK) receptor, NKp80, a signaling lymphocyte associated molecule (SLAM) family, CD150, a degrunulation marker, CD107a, and a coreceptor, CD8β emerged as potential biomarkers for FMS to distinguish from HD. Additionally, a memory marker, CD44 and an inflammatory chemokine receptor, CXCR1 appeared possible markers for RA, while a homeostatic chemokine receptor, CXCR4 deserved for SpA to differentiate from FMS. Furthermore, the drug treatment interruption resulted in alternation of the expression of CCR4, CCR5, CXCR4, CD27, CD28, inducible costimulatory molecule (ICOS), CD127 (IL-7 receptor α), CD94, NKp80, an activation marker, CD69, an integrin family member, CD49d, and a dipeptidase, CD26, in FMS. Combined with the currently available

  13. Mucosal-associated invariant T cell is a potential marker to distinguish fibromyalgia syndrome from arthritis.

    Directory of Open Access Journals (Sweden)

    Chie Sugimoto

    Full Text Available Fibromyalgia (FM is defined as a widely distributed pain. While many rheumatologists and pain physicians have considered it to be a pain disorder, psychiatry, psychology, and general medicine have deemed it to be a syndrome (FMS or psychosomatic disorder. The lack of concrete structural and/or pathological evidence has made patients suffer prejudice that FMS is a medically unexplained symptom, implying inauthenticity. Furthermore, FMS often exhibits comorbidity with rheumatoid arthritis (RA or spondyloarthritis (SpA, both of which show similar indications. In this study, disease specific biomarkers were sought in blood samples from patients to facilitate objective diagnoses of FMS, and distinguish it from RA and SpA.Peripheral blood mononuclear cells (PBMCs from patients and healthy donors (HD were subjected to multicolor flow cytometric analysis. The percentage of mucosal-associated invariant T (MAIT cells in PBMCs and the mean fluorescent intensity (MFI of cell surface antigen expression in MAIT cells were analyzed.There was a decrease in the MAIT cell population in FMS, RA, and SpA compared with HD. Among the cell surface antigens in MAIT cells, three chemokine receptors, CCR4, CCR7, and CXCR1, a natural killer (NK receptor, NKp80, a signaling lymphocyte associated molecule (SLAM family, CD150, a degrunulation marker, CD107a, and a coreceptor, CD8β emerged as potential biomarkers for FMS to distinguish from HD. Additionally, a memory marker, CD44 and an inflammatory chemokine receptor, CXCR1 appeared possible markers for RA, while a homeostatic chemokine receptor, CXCR4 deserved for SpA to differentiate from FMS. Furthermore, the drug treatment interruption resulted in alternation of the expression of CCR4, CCR5, CXCR4, CD27, CD28, inducible costimulatory molecule (ICOS, CD127 (IL-7 receptor α, CD94, NKp80, an activation marker, CD69, an integrin family member, CD49d, and a dipeptidase, CD26, in FMS.Combined with the currently available

  14. IL-17 Production from T Helper 17, Mucosal-Associated Invariant T, and γδ Cells in Tuberculosis Infection and Disease.

    Science.gov (United States)

    Coulter, Felicity; Parrish, Amy; Manning, Declan; Kampmann, Beate; Mendy, Joseph; Garand, Mathieu; Lewinsohn, David M; Riley, Eleanor M; Sutherland, Jayne S

    2017-01-01

    IL-17-producing cells have been shown to be important in the early stages of Mycobacterium tuberculosis (Mtb) infection in animal models. However, there are very little data on the role of IL-17 in human studies of tuberculosis (TB). We recruited TB patients and their highly exposed contacts who were further categorized based on results from an IFN-γ-release assay (IGRA): (1) IGRA positive (IGRA + ) at recruitment (latently TB infected), (2) IGRA negative (IGRA - ) at recruitment and 6 months [non-converters (NC)], and (3) IGRA - at recruitment and IGRA + at 6 months (converters). Whole blood was stimulated with mycobacterial antigens and analyzed using T helper (Th) 17 multiplex cytokine assays. Th17, Vγ9Vδ2 + , and CD161 ++ Vα7.2 + mucosal-associated invariant T (MAIT) cells were analyzed by flow cytometry. The majority of IL-17 was produced by CD26 + CD4 + Th17 cells (median 71%) followed by γδ T cells (6.4%) and MAIT cells (5.8%). TB patients had a significantly lower proportion of Th17 cells and CD4 + CD161 + Vα7.2 + cells producing both IL-17 and IFN-γ compared to LTBI subjects. IGRA NC had significantly lower levels of CD26 - CD4 + and CD8 + MAIT cells producing IL-17 compared to IGRA C but had significantly higher levels of IL-17A, IL-17F, IL-21, and IL-23 in ESAT-6/CFP-10-stimulated supernatants compared to IGRA C. These data provide new insights into the role of IL-17 and IL-17-producing cells at three key stages of the Mtb infection spectrum.

  15. Core Design Studies for a 300 MWe TRU Burner Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Song, Hoon; Kim, Sang Ji; Kim, Yeong Il [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2009-10-15

    KAERI has been developing the KALIMER-600 core design with a breakeven fissile conversion ratio. The core is loaded with a ternary metallic fuel (TRU-U-10Zr), and the breakeven characteristics are achieved without any blanket assembly. As an alternative plan, a KALIMER-600 burner core design has also been performed. In the early days of a fast reactor, the main purpose was an economical use of a uranium resource, but nowadays, in addition to the maximum utilization of a uranium resource, the burning of high level radioactive waste is taken as an additional interest for the harmony with the environment. In this paper, a 300 MWe burner core design is presented to demonstrate reactor performance for the reference KALIMER-600 burner. As a means to flatten the power distribution, instead of a single fuel enrichment scheme adapted in the design of the KALIMER-600 burner, the two enrichment zoning approach was adapted. Considering that the TRU fuel may not be qualified due to limited database, the uranium core was designed to permit the TRU core operation to cover after the uranium core is operated at an early stage.

  16. La escuela primaria, un lugar privilegiado para la evaluación kinesiológica.

    OpenAIRE

    Retondo, Marianela

    2010-01-01

    El presente trabajo se emprendió con el propósito de conocer la incidencia de las alteraciones posturales en los niños de 4º a 6º grado de la escuela primaria, el conocimiento de los padres sobre las mismas, y corroborar si los niños que presentaban alteraciones realizaban rehabilitación kinesiológica. La población de estudio estuvo compuesta por los niños de 4º a 6º grado que concurren a la escuela primaria Nº 22 de El Maitén provincia de Chubut. Allí se ...

  17. Entrevista a Arquímides González

    OpenAIRE

    Levi, Enrique Jaramillo

    2012-01-01

    Nació en Managua, Nicaragua en 1972. Ha publicado las novelas La muerte de Acuario en el 2002, y Qué sola estás Maité en 2007, el libro de relatos Tengo un mal presentimiento y la novela corta El fabuloso Blackwell en 2010; y en 2012 la novela Dos hombres y una pierna (UTP). Ha obtenido el iV Premio internacional sexto Continente de relato Negro en España en enero de 2011; el ii Premio Centroamericano de Novela Corta de Honduras en 2010; y fue ganador en 2009 del Certamen para Publicación de ...

  18. Simulation and Animation of the Cherry Point, North Carolina Naval Aviation Depot Proposed Engine Blade and Vane Rework Facility

    Science.gov (United States)

    1988-11-10

    mg ’ ilel Ex::;erirrent f ile is given a ",.E" e>:.-Aension. Once...selecting option KE...’:> > , or <F.>. Ecape returns the user t.,-, the Main Menu. CHERRY FOINT NAVAL AVIATION DEPOT ANIMATION MENU GD TO CINEMA MENU...t. 1~~~~~C ’.K T ’ FOE(7D;- OPT I ON?:" : MH=;:8 1 ’ jK’rgs. 1 LY’ 1 7)K: MG RE E’’ 1 71-16 MAs $ SF0R D" 1 ,(𔄁t) MtS’ $FE MAGENTA": * 47:,-; MAIt

  19. Mustamäe Maarja Magdaleena kiriku arhitektuurivõistlus = Architecture competition for Mustamäe`s Church of Mary Magdalene / Pille Epner

    Index Scriptorium Estoniae

    Epner, Pille

    2013-01-01

    Arhitektuurikonkursist, võidutööst "Fiat Lux" (arhitektid Risto Parve, Kai Süda, Martin Kinks, Margit Valma, arhitektuuriteadlane Mait Väljas, Karisma Arhitektid), 2. koha pälvinud tööst "Õhuke Koht" (Pille Noole, Üllar Ambos, Kaisa Lasner, Kerttu Karjust, Jiannis Lykouras, Arhitektuurinurk), 3. koha pälvinud tööst "Tee" (Villem Tomiste, Stuudio Tallinn). Loetletud ostupreemia ja kolm tunnustuse pälvinud võistlustööd

  20. Malting and brewing qualities of some Nigerian rice (Oryza sativa L.) varieties and some thoughts on the assessment of malts from tropical cereals.

    Science.gov (United States)

    Okafor, N; Iwouno, J

    1990-06-01

    The maiting qualities of six varieties of Nigerian rice were studied and compared with malts from sorghum and barley. A minimum of seven days was necessary for maximum yield of extract from malted rice. The beer brewed from the six rice malts were similar to each other and to those from sorghum and barley in analytical properties. The appropriateness of using methods designed for assessing barley malt should be re-examined for studying malts from tropical cereals. Meanwhile, it should be sufficient to determine the extract and the nitrogen content of the wort using the European Brewing methods to assess a tropical cereal for mall.

  1. Modernistlik ruumikontseptsioon ja nõukogude ideoloogia kohtuvad Viru hotellis / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2006-01-01

    Ajavahemikul 1964-1968 arhitektide Henno Sepmanni ja Mart Pordi poolt projekteeritud ning 1972. a. valminud Viru hotellist Tallinnas, põhjalikum ülevaade hoone interjöörist. Sisearhitektid Väino Tamm, Vello Asi, Taevo Gans, Mait Summatavet ja Loomet Raudsepp. II korruse naiste juuksuri ruumid kujundas Kirsti Laanemaa. II korruse banketisaalis oli Mari Adamsoni gobelään "Tare", suures restoranisaalis Aet Andresma-Tamme ja Mare Soovik-Lobjakase klaaskompositsioon "Pilved", Viru väljakul Edgar Viiese skulptuur "Merepiiga" (1981)

  2. 24th Annual Canadian Conference on HIV/AIDS Research/24e Congr?s Annuel Canadien de Recherche sur le VIH/sida CAHR Committees / Comit?s de l?ACRV

    OpenAIRE

    Hogg, Robert; Hogg, Robert; Hart, Trevor; Tan, Darrell; Hart, Trevor; Tan, Darrell; Boily-Larouche, Genevi?ve; Lajoie, Julie; Omollo, Kenneth O; Cheruiyot, Julianna; Njoki, Jane; Kimani, Makubo; Oyugi, Julius; Kimani, Joshua; Fowke, Keith R

    2015-01-01

    BACKGROUND: The C-type lectin CD161 is expressed by CD4+ and CD8+ T cells sharing conserved transcriptional and functional signature. CD4+ T cells with type-17 profiles derived from CD161+ precursors and CD161-expressing CD8+ T cells share the same differentiation profile and include the unique anti-bacterial CD161++ mucosal-associated invariant T cells (MAIT) expressing invariant TCR V?7.2. During HIV infection, circulating cells harbouring the signature of CD161+ cells are impaired in blood...

  3. Kõrgkoole ootab liitumine : valitsus kavatseb kuuest riigiülikoolist jätta alles kolm-neli / Eda-Liis Kann

    Index Scriptorium Estoniae

    Kann, Eda-Liis

    2000-01-01

    Ülikoolide võimalikust liitumisest, TPÜ, TTÜ ja TÜ koostööst teiste kõrgkoolidega. Kommenteerivad haridusminister Tõnis Lukas, TPÜ rektor Mait Arvisto, Eesti Kõrgema Kommertskooli rektor Madis Habakuk, Virumaa Kõrgkooli rektor Heino Türkson, TTÜ rektor Olav Aarna, Eesti Humanitaarinstituudi rektor Mikko Lagerspetz, TÜ õppeprorektor Volli Kalm, Eesti-Ameerika Ärikolledzi rektor Aleksander Lukjanov, Eraakadeemia Nord rektor Ene Grauberg, Sotsiaalteaduste Erakõrgkooli Veritas rektor Renate Talts, Tallinna Tehnikakõrgkooli rektor Arvi Altmäe, Concordia Rahvusvahelise Ülikooli rektor Mart Susi ja EPMÜ rektor Henn Elmet

  4. HERING TORRES, Max; ROJAS, Nelson A. (Eds.). Microhistorias de la transgresión. Bogotá: Universidad Nacional de Colombia, Universidad Cooperativa de Colombia, Universidad del Rosario, 2015. 483 p.

    OpenAIRE

    Yie Garzón, Soraya Maite

    2017-01-01

    HERING TORRES, Max; ROJAS, Nelson A. (Eds.). Microhistorias de la transgresión. Bogotá: Universidad Nacional de Colombia, Universidad Cooperativa de Colombia, Universidad del Rosario, 2015. 483 p.Soraya Maite Yie GarzónUniversidade Estadual de Campinas (Unicamp)Pontifícia Universidad Javeriana (PUJ/Colombia) El libro Microhistorias de la trasgresión, publicado el año pasado por las universidades Nacional de Colombia, del Rosario y Cooperativa de Colombia, y editado por los historiadores colom...

  5. Kunstide sünesteesia. Tasapinnalise visuaali ja muusika suhted / Einike Leppik

    Index Scriptorium Estoniae

    Leppik, Einike

    2010-01-01

    Uuritakse ja analüüsitakse kunstide sünesteesia printsiipe, ajaloolist kujunemist ja seoseid kujutava kunsti ja muusika loomisel. Lähtutud on 20. sajandil alguse saanud ja tänapäevani kestvatest arengutest kunstis - kunsti piiride hägustumisest, laienemisest ning nähtustest, mis nende arengutega kaasas on käinud 1890-1960-ndateni. Tõmmatakse paralleele Kandinsky abstraktsete impressioonide ja Schönbergi atonaalse helikeele, Claude Monet' maalide ja Claude Debussy muusika vahel, Čiurlionise kui kunstniku ja muusiku fuugamaastike, Eric Satie sünesteetilise kunsti ja John Cage'i jt. loomingu vahel. Praktilise tööna on 33 joonistusest kokku pandud installatsioon "Joon", mille põhjal komponeeris muusika EMTA tudeng Mait Jüriado

  6. Interactions between the microbiota and innate and innate-like lymphocytes.

    Science.gov (United States)

    Constantinides, Michael G

    2018-03-01

    The microbiota, which consists of commensal bacteria, fungi, and viruses, limits the colonization of pathogens at barrier tissues and promotes immune homeostasis. The latter is accomplished through the induction and regulation of both innate and adaptive immune responses. Innate lymphocytes, which include the type-1 innate lymphoid cell (ILC1), NK cell, type-2 innate lymphoid cell (ILC2), type-3 innate lymphoid cell (ILC3), and lymphoid tissue inducer (LTi) cell populations, and innate-like lymphocytes, such as NKT cells, mucosal-associated invariant T (MAIT) cells, and γδ T cells, are uniquely capable of responding to the microbiota due to their tissue localization and rapid primary responses. In turn, through their effector functions, these lymphocyte populations modulate the composition of the microbiota and maintain the segregation of commensals. This review will focus on how innate and innate-like lymphocytes mediate the crosstalk with the microbiome. ©2017 Society for Leukocyte Biology.

  7. Anti-NKG2D mAb

    DEFF Research Database (Denmark)

    Vadstrup, Kasper; Bendtsen, Flemming

    2017-01-01

    with a wide range of cell types and proteins involved. Natural Killer Group 2D (NKG2D) is an activating receptor constitutively expressed on human Natural Killer (NK), γδ T, mucosal-associated invariant T (MAIT), CD56⁺ T, and CD8⁺ T cells. Activation of NKG2D triggers cellular proliferation, cytokine...... production, and target cell killing. Research into the NKG2D mechanism of action has primarily been focused on cancer and viral infections where cytotoxicity evasion is a concern. In human inflammatory bowel disease (IBD) this system is less characterized, but the ligands have been shown to be highly...... expressed during intestinal inflammation and the following receptor activation may contribute to tissue degeneration. A recent phase II clinical trial showed that an antibody against NKG2D induced clinical remission of CD in some patients, suggesting NKG2D and its ligands to be of importance...

  8. Resistance as Organizational Change Dynamic:

    DEFF Research Database (Denmark)

    Plotnikof, Mie

    2017-01-01

    processes (Vangen & Winchester, 2013; Purdy, 2012; Plotnikof, 2016). Therefore, issues such as diversity management, process design and power are being investigated; however, central matters of e.g. resistance are surprisingly overseen – although resistance to political changes and welfare reform processes...... is not novel. As such, resistance is not given much attention in the governance literature, if so merely as a destructive obstacle or as lacking individual adaptability to change amongst stakeholders (Kumar et al., 2007). Contrary to this, resistance is a central theme to a stream of research on organizational...... change processes (Thomas & Davies, 2005; Ford, Ford & D’amelio, 2008; Hernes & Maitlis, 2010; Plotnikof, 2015). These studies take a discursive perspective to approach resistance and power as intertwined in change dynamics, thus offering theorizing valuable to governance studies concerning political...

  9. Therapeutic manipulation of natural killer (NK) T cells in autoimmunity: are we close to reality?

    Science.gov (United States)

    Simoni, Y; Diana, J; Ghazarian, L; Beaudoin, L; Lehuen, A

    2013-01-01

    T cells reactive to lipids and restricted by major histocompatibility complex (MHC) class I-like molecules represent more than 15% of all lymphocytes in human blood. This heterogeneous population of innate cells includes the invariant natural killer T cells (iNK T), type II NK T cells, CD1a,b,c-restricted T cells and mucosal-associated invariant T (MAIT) cells. These populations are implicated in cancer, infection and autoimmunity. In this review, we focus on the role of these cells in autoimmunity. We summarize data obtained in humans and preclinical models of autoimmune diseases such as primary biliary cirrhosis, type 1 diabetes, multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, psoriasis and atherosclerosis. We also discuss the promise of NK T cell manipulations: restoration of function, specific activation, depletion and the relevance of these treatments to human autoimmune diseases. © 2012 The Authors. Clinical and Experimental Immunology © 2012 British Society for Immunology.

  10. Procedure for obtaining visas for Switzerland and France - Signature rights

    CERN Multimedia

    2016-01-01

    In accordance with the Status Agreements with CERN, Switzerland and France facilitate the entry of members of the Organization’s personnel on to their territories. Where relevant, detailed procedures for obtaining visas apply.   Within the framework of those procedures, only the following individuals are authorised to initiate the Note verbale procedure as well as to sign the Official Invitation Letters and the Conventions d’accueil. Kirsti ASPOLA (EP – CMO) Maite BARROSO LOPEZ (IT – DI) Catherine BRANDT (DG – DI) Michelle CONNOR (TH – GS) Gaëlle DUPERRIER (EP – AGS) Patrick FASSNACHT (EP – ADO) Fernando FERNANDEZ SAVORGNANO (HR – TA) Nathalie GRÜB (EP – AGS) Laurie HEMERY (BE – ASR) Cécile NOELS (ATS – DO) Tania PARDO (EP – AGS) Maria QUINTAS (HR – TA) Kate RICHARDSON (EP –  AGS) Jeanne ROSTANT (TH – GS)...

  11. The QUIJOTE TGI cryomechanics

    Science.gov (United States)

    Sánchez-de-la-Rosa, V.; Vega-Moreno, A.; Cózar-Castellano, J.; Aguiar-González, M.; Galtress, A.; Génova-Santos, R.; Gómez-Reñasco, F.; Hoyland, R.; Martinis, L.; Melhuish, S. J.; Pérez-de Taoro, M. R.; Piccirillo, L.; Rebolo-López, R.; Rubiño-Martín, J. A.; Viera-Curbelo, T. A.

    2016-07-01

    The QUIJOTE (Q-U-I JOint Tenerife) CMB Experiment is operating at the Teide Observatory with the aim of characterizing the polarization of the CMB and other processes of Galactic and extragalactic emission in the frequency range of 10-40GHz and at large and medium angular scales. The QUIJOTE CMB experiment consists of two telescopes installed inside a single enclosure, and three instruments, the MFI (multi-frequency 10-30GHz), the TGI (26-36 GHz) and the FGI (37-47 GHz). The first QUIJOTE telescope and the MFI instrument have been in operation at the Observatory since November 2012. In this poster we present the TGI cryostat and optomechanics status, including their design, MAIT, and thermal clamp developments.

  12. Ärma talu ehitanud Aus Invest müüdi Panama riiulifirmale maha / Kadri Paas

    Index Scriptorium Estoniae

    Paas, Kadri, 1982-

    2007-01-01

    Ärma talu ehitanud Aus Invest OÜ ei ole maksnud tööde eest kõigile alltöövõtjatele. Proua Evelin Ilvese sõnul on Ermamaa peatöövõtjale kõigi kokkulepitud tööde eest maksnud. 2007. a. mais müüsid Aivar Aus ja Mait Aus Tartu maakohtu registriosakonna andmetel Aus Invest OÜ Panamal registreeritud riiulifirmale Arliana Enterprises Corp. Vt. samas: Nõunik sekkus presidendi teleintervjuusse. Kui telekanali TV3 Lõuna-Eesti reporter Valgamaal visiidil viibivalt Toomas Hendrik Ilveselt ja proua Evelin Ilveselt Ärma talu ehitusega kaasnenud võlgade kohta aru päris, sekkus kõnelusse presidendi avalike suhete nõunik Toomas Sildam. Vt. ka lk. 10: Urmo Soonvald. Ärma triibulised. Ajakirjanik ootab Ärma talu probleemidega seoses suuremat avalikustamist

  13. Raamatud

    Index Scriptorium Estoniae

    2008-01-01

    Katrin Kivimaa "Kinnitused ja vastuväited : tekste kunstist, pildikultuurist ja kirjutamisest 1995-2007" (kunst.ee, 2008, toimetanud Heie Treier, kujundanud Tõnu ja Ande Kaalep), Peeter Linnap "Fotoloogia" (Jutulind, 2008, kujundanud Atko Remmel), "Arhitektuur lõpmatuseni : Leonhard Lapini kujunemine ja olemine arhitektuuris" (Eesti Arhitektuurimuuseum, 2007, koostanud Mait Väljas, toimetanud Karin Hallas-Murula, kujundanud Tiit Jürna), "Leonhard Lapin. Koodid" (Eesti Kunstimuuseum, 2007, toimetanud Renita Raudsepp, kujundanud T. Jürna), L. Lapin "5 loengut" (Eesti Kunstiakadeemia, 2008, eessõna: Signe Kivi, kujundanud Angelika Schneider), "Kuus baltisaksa kunstnikku" (Baltisaksa Kultuuri Selts Eestis, 2008, koostanud Anne Untera, kujundanud Inga Heamägi), "Ann Audova : kumisev valgus (Eesti Kunstimuuseum, 2007, koostanud Ülle Kruus ja Enn Lillemets, kujundanud Adam Kaarma), "Paul Reeweer : väike kavandite raamat" (koostanud Helen Maran-Poll, kujundanud Anu Purre)

  14. Study on integrated TRU multi-recycling in sodium cooled fast reactor CDFR

    International Nuclear Information System (INIS)

    Hu Yun; Xu Mi; Wang Kan

    2010-01-01

    In view of recently proposed closed fuel cycle strategy which would recycle the integrated transuranics (TRU) from PWR spent fuel in the fast reactors, the neutronics characteristics of TRU recycled in China Demonstration Fast Reactor (CDFR) are studied in this paper. The results show that loading integrated TRU to substitute pure Pu as driver fuel will mainly make the influence on sodium void worth and negligible effects on other parameters, and hence TRU recycling in CDFR is feasible from viewpoint of core neutronics. If TRU is multi-recycled, the variation of TRU composition depends on fuel types and the ratio of TRU and U when recycling. It is indicated that, when TRU is multi-recycled in CDFR with MOX fuel, the minor actinides (MA) fraction in TRU will firstly decrease to ∼7.24% (minimum) within 8 TRU recycle times and then slowly increase to ∼7.7% after 20 TRU recycle times; while when TRU is multi-recycled in CDFR with metal fuel (TRU-U-10Zr), the MA fraction in TRU will gradually approach to an equilibrium state with the MA fraction of ∼3.8%, demonstrating better MA transmutation effect in metal fuel core. No matter 7.7 or 3.8%, they are both lower than ∼10% in PWR spent fuel with burnup of 45 GWd/tU, which presents satisfying effect of MA amount controlling for TRU multi-recycling strategy. On the other hand, the corresponding recycling parameters such as TRU heat release and neutron emission rate are also much lower in metal fuel than those in MOX fuel. Moreover, TRU recycled in metal fuel will bring greater fissile Pu isotopes equilibrium fraction due to better breeding capability of metal fuel. Finally, it could be summarized that integrated TRU multi-recycling in fast reactor can make contributions to both breeding and transmutation, and such strategy is a prospective closed fuel cycle manner to achieve the object of effective control of cumulated MA amount and sustainable development of nuclear energy.

  15. Design of an x-ray telescope optics for XEUS

    Science.gov (United States)

    Graue, Roland; Kampf, Dirk; Wallace, Kotska; Lumb, David; Bavdaz, Marcos; Freyberg, Michael

    2017-11-01

    The X-ray telescope concept for XEUS is based on an innovative high performance and light weight Silicon Pore Optics technology. The XEUS telescope is segmented into 16 radial, thermostable petals providing the rigid optical bench structure of the stand alone XRay High Precision Tandem Optics. A fully representative Form Fit Function (FFF) Model of one petal is currently under development to demonstrate the outstanding lightweight telescope capabilities with high optically effective area. Starting from the envisaged system performance the related tolerance budgets were derived. These petals are made from ceramics, i.e. CeSiC. The structural and thermal performance of the petal shall be reported. The stepwise alignment and integration procedure on petal level shall be described. The functional performance and environmental test verification plan of the Form Fit Function Model and the test set ups are described in this paper. In parallel to the running development activities the programmatic and technical issues wrt. the FM telescope MAIT with currently 1488 Tandem Optics are under investigation. Remote controlled robot supported assembly, simultaneous active alignment and verification testing and decentralised time effective integration procedures shall be illustrated.

  16. 7th Symposium on Computational Statistics

    CERN Document Server

    Lauro, N; Rizzi, A

    1986-01-01

    When dealing with the design or with the application of any technical system, which is not quite simple and trivial, one has to face to the problem to determine the allowable de­ viations of the system functions and the optimal vector of system parameter tolerances. The need for the solution of this problem is stimulated with various serious economic and maite­ nance aspects, between them the tendency to reach the minimal production cost, the maximal system operation reliability are the most frequent. Suppose that we are dealing with an system S, consisting of N components represented by the system parame­ ters xi' i = 1, 2 . . . N, which are arranged in certain structu­ re so, that the K, system functions F k' k = 1, 2 . . . IG , expres­ sing the considered system properties, fullfil the condition F-FO~ AF, /1/ \\'Ihere F = l F k} Ie is the set of the actual system functions, FO = lFOk}~ is the set of the nominal system functions and A F = l A F k 1(;. } is the set 0 f the a 11 0 w a b 1 e s emf y s t u ...

  17. Immunology in the liver--from homeostasis to disease.

    Science.gov (United States)

    Heymann, Felix; Tacke, Frank

    2016-02-01

    The liver is a central immunological organ with a high exposure to circulating antigens and endotoxins from the gut microbiota, particularly enriched for innate immune cells (macrophages, innate lymphoid cells, mucosal-associated invariant T (MAIT) cells). In homeostasis, many mechanisms ensure suppression of immune responses, resulting in tolerance. Tolerance is also relevant for chronic persistence of hepatotropic viruses or allograft acceptance after liver transplantation. The liver can rapidly activate immunity in response to infections or tissue damage. Depending on the underlying liver disease, such as viral hepatitis, cholestasis or NASH, different triggers mediate immune-cell activation. Conserved mechanisms such as molecular danger patterns (alarmins), Toll-like receptor signalling or inflammasome activation initiate inflammatory responses in the liver. The inflammatory activation of hepatic stellate and Kupffer cells results in the chemokine-mediated infiltration of neutrophils, monocytes, natural killer (NK) and natural killer T (NKT) cells. The ultimate outcome of the intrahepatic immune response (for example, fibrosis or resolution) depends on the functional diversity of macrophages and dendritic cells, but also on the balance between pro-inflammatory and anti-inflammatory T-cell populations. As reviewed here, tremendous progress has helped to understand the fine-tuning of immune responses in the liver from homeostasis to disease, indicating promising targets for future therapies in acute and chronic liver diseases.

  18. CD1 and mycobacterial lipids activate human T cells.

    Science.gov (United States)

    Van Rhijn, Ildiko; Moody, D Branch

    2015-03-01

    For decades, proteins were thought to be the sole or at least the dominant source of antigens for T cells. Studies in the 1990s demonstrated that CD1 proteins and mycobacterial lipids form specific targets of human αβ T cells. The molecular basis by which T-cell receptors (TCRs) recognize CD1-lipid complexes is now well understood. Many types of mycobacterial lipids function as antigens in the CD1 system, and new studies done with CD1 tetramers identify T-cell populations in the blood of tuberculosis patients. In human populations, a fundamental difference between the CD1 and major histocompatibility complex systems is that all humans express nearly identical CD1 proteins. Correspondingly, human CD1 responsive T cells show evidence of conserved TCRs. In addition to natural killer T cells and mucosal-associated invariant T (MAIT cells), conserved TCRs define other subsets of human T cells, including germline-encoded mycolyl-reactive (GEM) T cells. The simple immunogenetics of the CD1 system and new investigative tools to measure T-cell responses in humans now creates a situation in which known lipid antigens can be developed as immunodiagnostic and immunotherapeutic reagents for tuberculosis disease. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  19. The MUSE project from the dream toward reality

    Science.gov (United States)

    Callier, P.; Accardo, M.; Adjali, L.; Anwand, H.; Bacon, R.; Bauer, S. M.; Biswas, I.; Boudon, D.; Brau-Nogué, S.; Brotons, L.; Capoani, L.; Contini, T.; Daguisé, E.; Deiries, S.; Delabre, B.; Dubois, J.-P.; Dupieux, M.; Dupuis, C.; Fechner, T.; Fleischmann, A.; François, M.; Gallou, G.; Gharsa, T.; Glindemann, A.; Gojak, D.; Hansali, G.; Hahn, T.; Jarno, A.; Kelz, A.; Koehler, C.; Kosmalski, J.; Laurent, F.; Le Floch, M.; Lizon, J.-L.; Loupias, M.; Manescau, A.; Monstein, C.; Nicklas, H.; Olaya, J.-C.; Parès, L.; Pasquini, L.; Pécontal-Rousset, A.; Petit, C.; Popow, E.; Reiss, R.; Remillieux, A.; Renault, E.; Roth, M.; Rupprecht, G.; Serre, D.; Streicher, O.; Stuik, R.; Vernet, J.; Weilbacher, P.; Wisotzki, L.; Yerle, N.

    2010-07-01

    MUSE (Multi Unit Spectroscopic Explorer) is a second generation instrument developed for ESO (European Southern Observatory) to be installed on the VLT (Very Large Telescope) in year 2012. The MUSE project is supported by a European consortium of 7 institutes. After a successful Final Design Review the project is now facing a turning point which consist in shifting from design to manufacturing, from calculation to test, ... from dream to reality. At the start, many technical and management challenges were there as well as unknowns. They could all be derived of the same simple question: How to deal with complexity? The complexity of the instrument, of the work to de done, of the organization, of the interfaces, of financial and procurement rules, etc. This particular moment in the project life cycle is the opportunity to look back and evaluate the management methods implemented during the design phase regarding this original question. What are the lessons learn? What has been successful? What could have been done differently? Finally, we will look forward and review the main challenges of the MAIT (Manufacturing Assembly Integration and Test) phase which has just started as well as the associated new processes and evolutions needed.

  20. The Effect of Mercury Mining Activities on Oak Forest in the Almaden Area; El Encinar en el Distrito Minero de Almaden y su Afectacion por la Mineria del Mercurio

    Energy Technology Data Exchange (ETDEWEB)

    Villadoniga, M.; Sierra, M.J.; Millan, R.

    2009-07-01

    This scientific-technical report is the result of the research work carried out by Maite Villadoniga Garcia, to obtain the Master's Final Project, this has been developed at the Unit of Soil Degradation in the Department of Environment at CIEMAT. Two main reasons are important for the study of the vegetation in Almaden, firstly to ascertain the state in which they find the different landscapes surrounding the mine and secondly, it would be interesting to know the potential applications for recovery areas, degraded by this type of mining. This report presents the initial analysis of a natural area where there has not been activity related to mining of mercury, but their lithologic conditions and proximity to the mine of Almaden (within 3 km) make it a space in which they are both elevated mercury concentrations in soil (1.25 to 35.55 mg kg{sup -}1) and plant species (Quercus ilex: 0.10-2.29 mg kg{sup -}1; Pseudovernia sp. 1.10-21.06 mg kg{sup -}1). We can conclude after this study that the natural vegetation of the area if they had been affected by years of mining, although not find any obvious signs of damage to these ecosystems and that different factors affect the uptake of mercury by of different species. (Author) 37 refs.

  1. A Typical Immune T/B Subset Profile Characterizes Bicuspid Aortic Valve: In an Old Status?

    Directory of Open Access Journals (Sweden)

    Carmela R. Balistreri

    2018-01-01

    Full Text Available Bicuspid valve disease is associated with the development of thoracic aortic aneurysm. The molecular mechanisms underlying this association still need to be clarified. Here, we evaluated the circulating levels of T and B lymphocyte subsets associated with the development of vascular diseases in patients with bicuspid aortic valve or tricuspid aortic valve with and without thoracic aortic aneurysm. We unveiled that the circulating levels of the MAIT, CD4+IL−17A+, and NKT T cell subsets were significantly reduced in bicuspid valve disease cases, when compared to tricuspid aortic valve cases in either the presence or the absence of thoracic aortic aneurysm. Among patients with tricuspid aortic valve, these cells were higher in those also affected by thoracic aortic aneurysm. Similar data were obtained by examining CD19+ B cells, naïve B cells (IgD+CD27−, memory unswitched B cells (IgD+CD27+, memory switched B cells (IgD−CD27+, and double-negative B cells (DN (IgD−CD27−. These cells resulted to be lower in subjects with bicuspid valve disease with respect to patients with tricuspid aortic valve. In whole, our data indicate that patients with bicuspid valve disease show a quantitative reduction of T and B lymphocyte cell subsets. Future studies are encouraged to understand the molecular mechanisms underlying this observation and its pathophysiological significance.

  2. The Effect of Mercury Mining Activities on Oak Forest in the Almaden Area

    International Nuclear Information System (INIS)

    Villadoniga, M.; Sierra, M. J.; Millan, R.

    2009-01-01

    This scientific-technical report is the result of the research work carried out by Maite Villadoniga Garcia, to obtain the Master's Final Project, this has been developed at the Unit of Soil Degradation in the Department of Environment at CIEMAT. Two main reasons are important for the study of the vegetation in Almaden, firstly to ascertain the state in which they find the different landscapes surrounding the mine and secondly, it would be interesting to know the potential applications for recovery areas, degraded by this type of mining. This report presents the initial analysis of a natural area where there has not been activity related to mining of mercury, but their lithologic conditions and proximity to the mine of Almaden (within 3 km) make it a space in which they are both elevated mercury concentrations in soil (1.25 to 35.55 mg kg - 1) and plant species (Quercus ilex: 0.10-2.29 mg kg - 1; Pseudovernia sp. 1.10-21.06 mg kg - 1). We can conclude after this study that the natural vegetation of the area if they had been affected by years of mining, although not find any obvious signs of damage to these ecosystems and that different factors affect the uptake of mercury by of different species. (Author) 37 refs.

  3. "Kes kaunis on, peab andma vastse võsu..." : [sonetid] / William Shakespeare ; tlk. Harald Rajamets, Ants Oras

    Index Scriptorium Estoniae

    Shakespeare, William, 1564-1616

    2006-01-01

    Sisu: "Kes kaunis on, peab andma vastse võsu..." ; "Sa peeglist näed: need palgejooned nüüd..." ; "Seesama aeg, mis kunstipeenelt voolib..." ; "Miks muusika teeb nukraks sind, kes ise..." ; "Ei, armastust ei tunne sinu rind..." ; "Nii ruttu, kui sa hääbud, uueks sirgud..." ; "Kui kuulen, kuidas aega mõõdab kell..." ; "Kuid miks sa ise tõhusamal moel..." ; "Kas suvepäeva sarnaseks sind kiita?..." ; "Aeg, õgard, küüned lõvil tömbiks kääna... ; "Ei veena peegel mind, et olen vana..." ; "Just nagu näitleja, kel kinni keel..." ; "Mu silm kui taidur võttis pilti teha..." ; "Mu armu isand, kelle truu vasall..." ; "Ma reisist väsinuna heidan sängi..." ; "Kui õnnest hüljatuna nutan sala..." ; "Kui vaikse leebe mõtte kohtu ette..." ; "Ma olen näinud küll, kuis tõusev päike..." ; "Ma tunnistan, et meid on siiski kaks..." ; "Nii nagu isa, vanadusest nõrka..." ; "Kui sulen laud, mu silmad hästi näevad..." ; "Nii ränk on reisida mul tüütul teel..." ; "Mis on su olemus, mis tuum su, miks..." ; "Ei kuningate uhked marmorsambad..." ; "Arm, uuenda end, nii et öelda sust..." ; "Kui uut ei olegi, vaid kõik on sama..." ; "Nii nagu lained ulgumerelt randa..." ; "Neiks päeviks, kui kord aeg mu armsal palge..." ; "Et näen, kuis aja käsi kõike lõhub..." ; "Kui pronksi, kivi, maad ja merd võib neelda..." ; "Mu tusk on ränk, nüüd surma kutsuks küll..." ; "Kui suren, ära leina mind sa kaua..." ; "Sa minus seda aastaaega näed..." ; "Mul sinust kirjutades arg on meel..." ; "Oo hüvasti! Liig kallis mul su hind..." ; "Siis vihka mind, kui pead, ja kohe praegu..." ; "Mõnd uhkeks teeb ta kunst, mõnd sünnipära..." ; "Sust eemal olin kevadel, mu arm..." ; "Kui möödaläinud aja kroonikais..." ; "Mis on veel ajul paberile kanda..." ; "Jah, tõsi, olen käinus siin ja seal..." ; "Ma uskuda ei saa, et murda suudab..." ; "On parem olla halb kui halvaks peetud..." ; "Ei, aeg, sa ära hoople, et mind muudad..." ; "Mu muusika, kui muusikat sa teed

  4. CD8αα expression marks terminally differentiated human CD8+ T cells expanded in chronic viral infection

    Directory of Open Access Journals (Sweden)

    Lucy Jane Walker

    2013-08-01

    Full Text Available The T cell co-receptor CD8αβ enhances T cell sensitivity to antigen, however studies indicate CD8αα has the converse effect and acts as a co-repressor. Using a combination of Thymic Leukaemia antigen (TL tetramer, which directly binds CD8αα, anti-CD161 and anti-Vα7.2 antibodies we have been able for the first time to clearly define CD8αα expression on human CD8 T cells subsets. In healthy controls CD8αα is most highly expressed by CD161 bright (CD161++ mucosal associated invariant T (MAIT cells, with CD8αα expression highly restricted to the TCR Vα7.2+ cells of this subset. We also identified CD8αα-expressing populations within the CD161 mid (CD161+ and negative (CD161- non-MAIT CD8 T cell subsets and show TL-tetramer binding to correlate with expression of CD8β at low levels in the context of maintained CD8α expression (CD8α+CD8βlow. In addition, we found CD161-CD8α+CD8βlow populations to be significantly expanded in the peripheral blood of HIV-1 and hepatitis B (mean of 47% and 40% of CD161- T cells respectively infected individuals. Such CD8αα expressing T cells are an effector-memory population (CD45RA-, CCR7-, CD62L- that express markers of activation and maturation (HLA-DR+, CD28-, CD27-, CD57+ and are functionally distinct, expressing greater levels of TNF-α and IFN-γ on stimulation and perforin at rest than their CD8α+CD8βhigh counterparts. Antigen-specific T cells in HLA-B*4201+HIV-1 infected patients are found within both the CD161-CD8α+CD8βhigh and CD161-CD8α+CD8βlow populations. Overall we have clearly defined CD8αα expressing human T cell subsets using the TL-tetramer, and have demonstrated CD161-CD8α+CD8βlow populations, highly expanded in disease settings, to co-express CD8αβ and CD8αα. Co-expression of CD8αα on CD8αβ T cells may impact on their overall function in-vivo and contribute to the distinctive phenotype of highly differentiated populations in HBV and HIV-1 infection.

  5. Cuerpos desplazados. Género, deporte, y protagonismo cultural en la plaza vasca

    Directory of Open Access Journals (Sweden)

    Olatz González-Abrisketa

    2013-01-01

    Full Text Available Este artículo reflexiona acerca de la identificación metonímica que se produce entre el cuerpo masculino y la comunidad vasca y cómo dicha identificación genera una exclusión sistemática de las mujeres de los espacios de protagonismo cultural. Para ello, va a analizar cómo se escenifica dicho protagonismo en el deporte de la pelota, un deporte que ha contribuido a conformar el imaginario vasco y cuya modalidad más popular es exclusivamente masculina. La pelota ha configurado las plazas de muchas villas y pueblos del País Vasco, así como física y moralmente los cuerpos emplazados en ellas. El lugar para el juego de pelota, el frontón, es el espacio que la comunidad vasca utiliza para ubicar sus eventos más significativos. La pelota es el juego prototípico de dicho espacio. Desvelando la cadena de significantes que genera su escenificación, es posible desvelar el imaginario que impide que las mujeres devengan protagonistas en el contexto de representación cultural vasca. El artículo incopora la historia de vida de una de ellas, la pelotari navarra Maite Ruiz de Larramendi, quien fue obligada a abandonar la pelota cuando era una niña, e intenta ofrecer algunas claves para interpretar otros casos que trascienden sus límites etnográficos, como el de la atleta surafricana Caster Semenya.

  6. Žanr : suvelavastus? / Jaak Allik

    Index Scriptorium Estoniae

    Allik, Jaak, 1946-

    2007-01-01

    Kahekümnest suvisest teatriõhtust: Carlo Gozzi "Ronk" Tallinna Linnateatri lavaaugus (lavastaja Elmo Nüganen), Komöödiateatri suvetuuri lavastus "Elu parim puhkus" (lavastaja Ago-Endrik Kerge), muusikal "Tutvumiskuulutus" (lavastaja Mait Malmsten), Bernard Kangermanni laulumäng "Naabri Mari" (lavastaja Margus Vaher) ja Mara Zalite "Sirelikassid" (lavastaja Peeter Tammearu) Ugalas, Paul Barzi komöödia "Võimalik kohtumine" (lavastaja Raivo Trass) Vanemuise teatri suvelavastus Muhumaal Pädaste mõisas, muusikaline estraadietendus "Tähtede sadu", Endla "Tsirkus!!!" Paikuse-Reiu vabaõhulaval (autor ja lavastaja Tiit Palu), Andrus Kivirähki näidend "Uljas Neitsi" Laulasmaa Resort' rannametsas (lavastaja Taavi Teplenkov), Marti Kivastik "Eesti asi" (lavastaja Ingomar Vihmar) MTÜ Ühendus R.A.A.A.M. Viinistu kunstimuuseumi vabaõhulaval, Emajõe Suveteatri suvelavastus "Jumalaema kiriku kellamees" Victor Hugo romaani järgi (lavastaja Andres Dvinjaninov), "Muna EÜE ehk Viimane kava" (autor Lauri Vahtre, lavastaja Andrus Vaarik) Suure Munamäe vabaõhulaval, Aino Kalda "Reigi õpetaja" Kuressaares (lavastaja ja dramatiseerija Aare Toikka), Vana Baskini Teateris Pierre Chesnot "Kes aevastas?" (lavastaja Eino Baskin), Eduard Vilde romaani "Prohvet Maltsvet" ja vene kirjaniku Viktor Pelevini romaani aineil sündinud lavastus "Proffet" Albu vallas Kukenoosi rehealuses (lavastaja Mart Koldits), Enn Vetemaa "Roosiaed" Raasiku vallas Kiviloo mõisas (lavastaja Eva Klemets), Jim Ashilevi "Portselansuits" (lavastaja Lauri Lagle) Eesti Teatriliidu saalis, Andres Keili "Rooside sõda" Leigo Järveteatris (lavastaja Tõnu Lensment), Võru Teatriateljee suvelavastus Madis Kõivu "Castrozza ehk illusionist" (lavastaja Taago Tubin), Villu Tamme "Haned võlgu" (lavastaja ja kunstnik Jaanika Juhanson) Teatrilabor Von Krahli teatris

  7. Probiotic Lactobacilli Modulate Staphylococcus aureus-Induced Activation of Conventional and Unconventional T cells and NK cells

    Directory of Open Access Journals (Sweden)

    Maria A Johansson

    2016-07-01

    Full Text Available Lactobacilli are probiotic commensal bacteria and potent modulators of immunity. When present in the gut or supplemented as probiotics, they beneficially modulate ex vivo immune responsiveness. Further, factors derived from several lactobacilli strains act immune regulato-ry in vitro. In contrast, Staphylococcus aureus (S. aureus is known to induce excessive T cell activation. In this study we aimed to investigate S. aureus-induced activation of human muco-sal associated invariant T cells (MAIT cells, γδ T cells, NK cells, as well as of conventional CD4+ and CD8+ T cells in vitro. Further, we investigated if lactobacilli-derived factors could modulate their activation.PBMC were cultured with S. aureus 161:2 cell free supernatant (CFS, staphylococcal en-terotoxin A or CD3/CD28-beads alone or in combination with Lactobacillus rhamnosus (L. rhamnosus GG-CFS or Lactobacillus reuteri (L. reuteri DSM 17938-CFS, and activation of T and NK cells was evaluated. S. aureus-CFS induced IFN-γ and CD107a expression as well as proliferation. Co-stimulation with lactobacilli-CFS dampened lymphocyte activation in all cell types analysed. Pre-incubation with lactobacilli-CFS was enough to reduce subsequent activation and the ab-sence of APC or APC-derived IL-10 did not prevent lactobacilli-mediated dampening. Final-ly, lactate selectively dampened activation of unconventional T cells and NK cells. In summary, we show that molecules present in the lactobacilli-CFS are able to directly dampen in vitro activation of conventional and unconventional T cells and of NK cells. This study provides novel insights on the immune modulatory nature of probiotic lactobacilli and suggests a role for lactobacilli in modulation of induced T and NK cell activation.

  8. Abatement of CO{sub 2} emissions in the European Union

    Energy Technology Data Exchange (ETDEWEB)

    Lesourne, J.; Keppler, J.H.; Jaureguy-Naudin, Maite; Smeers, Yves; Bouttes, Jean-Paul; Trochet, Jean-Michel; Dassa, Francois; Neuhoff, Karsten

    2008-07-01

    This first monograph of the Ifri program on European Governance and Geopolitics of Energy is devoted to the control of carbon dioxide emissions within the European Union. Since it is almost unanimously accepted that Greenhouse Gas emissions constitute the main cause of the observed increase of the world average temperature, the system implemented by the European Union to limit and decrease the CO{sub 2} emissions is a significant pillar of the EU energy policy, the two others being the acceptance by the Member States of long-term commitments (for instance on the future share of renewable energy sources in their energy balance sheet) and the establishment of an internal market for electricity and gas. Though simple in principle, the European Union Greenhouse Gas Emission Trading Scheme (EU ETS) is in fact rather complex, and only experts really understand its merits and its deficiencies. These deficiencies are real and will have to be corrected in the future for the system to be effective. At this moment, when the 2005-2007 trial phase of the EU ETS is ending, the monograph has the purpose to stimulate the discussion between experts and to enable all those interested in the topic to understand the issues and to take part in the public debates on the subject. The monograph contains five papers: - 'An Overview of the CO{sub 2} Emission Control System in the European Union' by Jacques Lesourne and Maite Jaureguy-Naudin. - 'Description and Assessment of EU CO{sub 2} Regulations' by Yves Smeers. - 'Assessment of EU CO{sub 2} Regulations' by Jean-Paul Bouttes, Jean-Michel Trochet and Francois Dassa. - 'Investment in Low Carbon Technologies, Policies for the Power Sector' by Karsten Neuhoff. - 'Lessons Learned from the 2005-2007 Trial Phase of the EU Emission Trading System' by Jan Horst Keppler

  9. Abatement of CO2 emissions in the European Union

    International Nuclear Information System (INIS)

    Lesourne, J.; Keppler, J.H.; Jaureguy-Naudin, Maite; Smeers, Yves; Bouttes, Jean-Paul; Trochet, Jean-Michel; Dassa, Francois; Neuhoff, Karsten

    2008-01-01

    This first monograph of the Ifri program on European Governance and Geopolitics of Energy is devoted to the control of carbon dioxide emissions within the European Union. Since it is almost unanimously accepted that Greenhouse Gas emissions constitute the main cause of the observed increase of the world average temperature, the system implemented by the European Union to limit and decrease the CO 2 emissions is a significant pillar of the EU energy policy, the two others being the acceptance by the Member States of long-term commitments (for instance on the future share of renewable energy sources in their energy balance sheet) and the establishment of an internal market for electricity and gas. Though simple in principle, the European Union Greenhouse Gas Emission Trading Scheme (EU ETS) is in fact rather complex, and only experts really understand its merits and its deficiencies. These deficiencies are real and will have to be corrected in the future for the system to be effective. At this moment, when the 2005-2007 trial phase of the EU ETS is ending, the monograph has the purpose to stimulate the discussion between experts and to enable all those interested in the topic to understand the issues and to take part in the public debates on the subject. The monograph contains five papers: - 'An Overview of the CO 2 Emission Control System in the European Union' by Jacques Lesourne and Maite Jaureguy-Naudin. - 'Description and Assessment of EU CO 2 Regulations' by Yves Smeers. - 'Assessment of EU CO 2 Regulations' by Jean-Paul Bouttes, Jean-Michel Trochet and Francois Dassa. - 'Investment in Low Carbon Technologies, Policies for the Power Sector' by Karsten Neuhoff. - 'Lessons Learned from the 2005-2007 Trial Phase of the EU Emission Trading System' by Jan Horst Keppler

  10. Aasta 1998 Tallinna Pedagoogikaülikoolis : [kroonika] / koost. Merike Määrits

    Index Scriptorium Estoniae

    1999-01-01

    Ülevaateartikkel TPÜ tähtsamatest sündmustest 1998.a. ja lõpetajate nimekiri. 13. märtsil̀98 toimus filoloogiateaduskonnas emakeelepäev. 29.apr.̀98 parafraseerisid Roueni ülikool ja TPÜ koostöö põhiprintsiibid. 5. mail̀98 korraldas TPÜ rektoraat vastuvõtu Eesti meistrivõistluste II koha saanud korv- ja võrkpallinaiskonnale. 4. nov.̀98 avati TPÜ filoloogiateaduskonnas slavistika kabinet. 7., 8. mail̀98 toimus TPÜ kultuuriteaduskonna korraldusel teaduskonverents "Eesti kultuur 1940. aastate teisel poolel". 28. jaan.̀98 avati TPÜs Euroopa Ülikoolide Infokeskus. 2. sept.̀98 avati TPÜ Haapsalu Kolledž. 5. okt.̀98 tähistat TPÜ-s õpetajate päeva. EV presidendi vastuvõtul käisid 1998.a. TPÜ cum laude lõpetanud üliõpilased. 3. dets.̀98 korraldas TPÜ rektor Mait Arvisto vastuvõtu ülikooli üliõpilaste teadustööde konkursi võitjatele ja nende juhendajatele. 27. veebr.̀98, sotsiaalteaduskonna päeval anti teaduskonna õppejõududele üle õppejõupreemid. 16. okt.̀98 tähistati piduliku aktusega TPÜ 79. aastapäeva. TPÜ lõpetajad 1998. 7.-8.dets.̀98 korraldas TPÜ sotsiaaltöö osakond koostöös sotsiaalministeeriumi vanuripoliitika komisjoniga konverentsi "Ühiskond igale eale". EV haridusministeeriumi poolt korraldatud üliõpilaste teadustööde konkursil tunnistati Reimo Rivise töö ama alagrupis III preemia vääriliseks, diplomid said Krista Kalberg, Mihkel Märtin, Maris Pallas, Kaire Parts, Merle Talvik. 16. dets.̀98 avasid Prantsusmaa suursaadik Jacques Subrenat ja kultuuriatašee Catherine Suard prantsuse keele lektoraadi

  11. Lasteaia ja lõbumaja vahel : Eesti proosa 2008 / Vaapo Vaher

    Index Scriptorium Estoniae

    Vaher, Vaapo, 1945-

    2012-01-01

    Ülevaade 2008. aasta eesti proosast. Pikemalt käsitletakse järgmisi autoreid ja nende teoseid: Mihkel Raud "Musta pori näkku", Olev Remsu "Musketäride muundumised", Rein Põder "Juba olnud", Juhan Nurme "Ligimene", Jaan Tangsoo "Méduse'i parv", Esta Aksli "Tare poole tõttaja", Mari Saat "Lasnamäe lunastaja", Peeter Morgen "Sõnum", Mait Raun "Dr. Mööbi seiklused Inglismaal", Andrei Hvostov "Võõrad lood" ja "Projektijuht Posse", Chaneldior "Kontrolli alt väljas", Vahur Afanasjev "Kosmos", Egon Ilisson "Isased", Jaak Leer "Kaks kabanossi ja Maaja", Kärt Hellerma "Sinine missa", Elo Viiding "Püha Maama", Toomas Raudam "Miks ma ei taha olla kirjanik?", Mart Kivastik "Kurb raamat", Jüri Tuulik "Räim, pisike kena kala", Tarmo Teder "12 jõulujuttu", Dagmar Lamp (koostaja) "Tule, ma jutustan sulle loo", Eia Uus "Kahe näoga jumal", Barthol Lo Mejor "Popdada 2007-2008", Anti Saar "Nemad kaks", Ketlin Priilinn "Liiseli võti" ja "Vaim", Aita Kivi "Lähedal", Marje Ernits "Hoia mu kätt", Kati Murutar "Naisena sündinud : kakskümmend aastat hiljem", Tuule Lind "Pööratud tuul", Siiri Laidla "Lihtne lugu, ehk, Senta suvepuhkus", Kätlin Padesaar "Veel üks paradiis", Aimée Beekman "Proovielu", Lehte Hainslau "Kolmkõla, ehk, 3 kõla", Ira Lember "Ööviiulid", Tamur Kusnets "Hundipäikese aeg : metsiku jahi algus", Kaupo Pähkel "Ehatähe rüütel", Arvo Valton "Ülemiste vanake", Tiit Aleksejev "Palveränd", Ants Eret "Afgaanide vang", Mario Merirand "Afganistani päevik", Leo Kunnas "Gort Ashryn", Rein Raud "Vend", Peeter Sauter "Beibi bluu", Marion Andra "Pimend", Kristjan Sander "13 talvist hetke", Helga Nõu "Peaaegu geenius, ehk, Schrödingeri kassi otsimas", Tiit Sepa "Eefa hüüdnimega Siug", Kaarel ja Klaara Kivi "Varandus seinal", Merike Jürjo "Mälestusteta maja", Rein Vahisalu "Viies kabinet", Aarne Biin "Mees otsib naist", Erik Tohvri "Ümberasujad" ja "Sulasest sai peremees", Arnold Laugus "Elav maa", Jüri v. Grauberg "Selguse poole", J

  12. Lasteaia ja lõbumaja vahel : eesti proosa 2008 / Vaapo Vaher

    Index Scriptorium Estoniae

    Vaher, Vaapo, 1945-

    2009-01-01

    Ülevaade 2008. aasta eesti proosast. Pikemalt käsitletakse järgmisi autoreid ja nende teoseid: Mihkel Raud "Musta pori näkku", Olev Remsu "Musketäride muundumised", Rein Põder "Juba olnud", Juhan Nurme "Ligimene", Jaan Tangsoo "Méduse'i parv", Esta Aksli "Tare poole tõttaja", Mari Saat "Lasnamäe lunastaja", Peeter Morgen "Sõnum", Mait Raun "Dr. Mööbi seiklused Inglismaal", Andrei Hvostov "Võõrad lood" ja "Projektijuht Posse", Chaneldior "Kontrolli alt väljas", Vahur Afanasjev "Kosmos", Egon Ilisson "Isased", Jaak Leer "Kaks kabanossi ja Maaja", Kärt Hellerma "Sinine missa", Elo Viiding "Püha Maama", Toomas Raudam "Miks ma ei taha olla kirjanik?", Mart Kivastik "Kurb raamat", Jüri Tuulik "Räim, pisike kena kala", Tarmo Teder "12 jõulujuttu", Dagmar Lamp (koostaja) "Tule, ma jutustan sulle loo", Eia Uus "Kahe näoga jumal", Barthol Lo Mejor "Popdada 2007-2008", Anti Saar "Nemad kaks", Ketlin Priilinn "Liiseli võti" ja "Vaim", Aita Kivi "Lähedal", Marje Ernits "Hoia mu kätt", Kati Murutar "Naisena sündinud : kakskümmend aastat hiljem", Tuule Lind "Pööratud tuul", Siiri Laidla "Lihtne lugu, ehk, Senta suvepuhkus", Kätlin Padesaar "Veel üks paradiis", Aimée Beekman "Proovielu", Lehte Hainslau "Kolmkõla, ehk, 3 kõla", Ira Lember "Ööviiulid", Tamur Kusnets "Hundipäikese aeg : metsiku jahi algus", Kaupo Pähkel "Ehatähe rüütel", Arvo Valton "Ülemiste vanake", Tiit Aleksejev "Palveränd", Ants Eret "Afgaanide vang", Mario Merirand "Afganistani päevik", Leo Kunnas "Gort Ashryn", Rein Raud "Vend", Peeter Sauter "Beibi bluu", Marion Andra "Pimend", Kristjan Sander "13 talvist hetke", Helga Nõu "Peaaegu geenius, ehk, Schrödingeri kassi otsimas", Tiit Sepa "Eefa hüüdnimega Siug", Kaarel ja Klaara Kivi "Varandus seinal", Merike Jürjo "Mälestusteta maja", Rein Vahisalu "Viies kabinet", Aarne Biin "Mees otsib naist", Erik Tohvri "Ümberasujad" ja "Sulasest sai peremees", Arnold Laugus "Elav maa", Jüri v. Grauberg "Selguse poole", J

  13. Is it homogeneous or heterogeneous catalysis derived from [RhCp*Cl2]2? In operando XAFS, kinetic, and crucial kinetic poisoning evidence for subnanometer Rh4 cluster-based benzene hydrogenation catalysis.

    Science.gov (United States)

    Bayram, Ercan; Linehan, John C; Fulton, John L; Roberts, John A S; Szymczak, Nathaniel K; Smurthwaite, Tricia D; Özkar, Saim; Balasubramanian, Mahalingam; Finke, Richard G

    2011-11-23

    Determining the true, kinetically dominant catalytically active species, in the classic benzene hydrogenation system pioneered by Maitlis and co-workers 34 years ago starting with [RhCp*Cl(2)](2) (Cp* = [η(5)-C(5)(CH(3))(5)]), has proven to be one of the most challenging case studies in the quest to distinguish single-metal-based "homogeneous" from polymetallic, "heterogeneous" catalysis. The reason, this study will show, is the previous failure to use the proper combination of: (i) in operando spectroscopy to determine the dominant form(s) of the precatalyst's mass under catalysis (i.e., operating) conditions, and then crucially also (ii) the previous lack of the necessary kinetic studies, catalysis being a "wholly kinetic phenomenon" as J. Halpern long ago noted. An important contribution from this study will be to reveal the power of quantitiative kinetic poisoning experiments for distinguishing single-metal, or in the present case subnanometer Rh(4) cluster-based catalysis, from larger, polymetallic Rh(0)(n) nanoparticle catalysis, at least under favorable conditions. The combined in operando X-ray absorption fine structure (XAFS) spectroscopy and kinetic evidence provide a compelling case for Rh(4)-based, with average stoichiometry "Rh(4)Cp*(2.4)Cl(4)H(c)", benzene hydrogenation catalysis in 2-propanol with added Et(3)N and at 100 °C and 50 atm initial H(2) pressure. The results also reveal, however, that if even ca. 1.4% of the total soluble Rh(0)(n) had formed nanoparticles, then those Rh(0)(n) nanoparticles would have been able to account for all the observed benzene hydrogenation catalytic rate (using commercial, ca. 2 nm, polyethyleneglycol-dodecylether hydrosol stabilized Rh(0)(n) nanoparticles as a model system). The results--especially the poisoning methodology developed and employed--are of significant, broader interest since determining the nature of the true catalyst continues to be a central, often vexing issue in any and all catalytic reactions

  14. Energy in India's Future: Insights

    International Nuclear Information System (INIS)

    Lesourne, J.; Ramsay, W.C.; Jaureguy-Naudin, Maite; Boillot, Jean-Joseph; Autheman, Nicolas; Ruet, Joel; Siddiqui, Zakaria; Zaleski, C. Pierre; Cruciani, Michel

    2009-01-01

    In the decades following India's independence from British rule in 1947, the West's image of India was summarized in three simple cliches: the world's largest democracy, an impoverished continent, and economic growth hampered by a fussy bureaucracy and the caste system, all in a context of a particular religion. These cliches are perhaps one of the reasons that the success of India's green revolution was recognized so late, a revolution that allowed the country to develop its agricultural sector and to feed its population. Since the 1990's, the easing of planning constraints have liberated the Indian economy and allowed it to embark on a more significant path of growth. New cliches have begun to replace the old: India will become a second China and, lagging by 10 to 20 years, will follow the same trajectory, with its development marked more by services and the use of renewable energy. However, these trends will not prevent primary energy demand from exploding. On the contrary, India faces difficult choices on how it increases clean, secure, affordable energy to all its citizens. Many of the choices are the same as found elsewhere, but on a scale matched only by China. The IFRI European Governance and Geopolitics of Energy Project intends this study to deepen public understanding of the magnitude of India's challenges. Various aspects of the serious energy problems are studied throughout this monograph. The authors have written freely on these matters without attempting to reconcile their different viewpoints. The first chapter, by Maite Jaureguy-Naudin and Jacques Lesourne, presents an overview of India's present and future energy system. The authors follow a prudent but realistic view of India's future. The second chapter, by Jean-Joseph Boillot, a French expert on India who has published several books and articles on this subject, and Nicolas Autheman, research fellow, describes in greater detail the specifics of India's economy and the actors who are now present

  15. Prevalence of conventional risk factors and lipid profiles in patients with acute coronary syndrome and significant coronary disease

    Directory of Open Access Journals (Sweden)

    González-Pacheco H

    2014-10-01

    Full Text Available Héctor González-Pacheco,1 Jesús Vargas-Barrón,2 Maite Vallejo,2 Yigal Piña-Reyna,3 Alfredo Altamirano-Castillo,1 Pedro Sánchez-Tapia,1 Carlos Martínez-Sánchez1 1Coronary Care Unit, National Institute of Cardiology in Mexico City, Mexico City, Mexico; 2Department of Clinical Research, National Institute of Cardiology in Mexico City, Mexico City, Mexico; 3Catheterization Laboratory, National Institute of Cardiology in Mexico City, Mexico City, Mexico Background: Among patients with coronary artery disease (CAD, 80%–90% present at least one conventional risk factor. On the other hand, lipid profile modification after a cardiovascular event related to acute coronary syndrome (ACS has been recognized. The prevalence of conventional risk factors and the lipid profile at the time of admission in patients with ACS and significant CAD (stenosis ≥50% determined through coronary angiography is not well described. Methods: We studied 3,447 patients with a diagnosis of ACS and significant CAD with stenosis ≥50%, as shown on angiography. We recorded the presence of conventional risk factors, including smoking, hypertension, dyslipidemia, and diabetes. In addition, we analyzed the lipid profiles within the first 24 hours of admission. We analyzed the studied population and compared findings according to sex.Results: Most patients (81.7% were male. ST-elevation myocardial infarction was present in 51.3% of patients, and non-ST-elevation acute coronary syndrome was present in 48.7%. The most frequent risk factor was smoking, which was present in 68% of patients, followed by hypertension (57.8%, dyslipidemia (47.5%, and diabetes (37.7%. In women, the most frequent risk factors were hypertension, diabetes, and dyslipidemia, whereas in men, smoking was the most frequent. We identified at least one risk factor in 95.7% of all patients, two or three risk factors in 62%, and four risk factors in 8.6% of patients. The lipid profile analysis revealed that

  16. Enhanced Th1/Th17 Functions of CD161+ CD8+ T Cells in Mucosal Tissues of Rhesus Macaques.

    Directory of Open Access Journals (Sweden)

    Namita Rout

    Full Text Available Expression of the C-type lectin-like receptor CD161 by human T cells is associated with type-17 responses, which play critical regulatory roles in immunity and inflammation at mucosal sites. However, the functions of CD161-expressing T cells in macaques, the pre-clinical model of several human diseases, remain unknown. This study examined the phenotypic and functional characteristics of CD161+ T cells in peripheral blood, mucosal tissues and lymph nodes of rhesus macaques. Majority of CD161-expressing T cells in peripheral blood and lung/intestinal mucosal tissues of rhesus macaques were found to be CD8+CD4- in phenotype. There was a significant enrichment of CD161+CD8+ T cells in the lungs and colonic mucosa (16.1%±6.6 and 16.8%±5.7 in comparison to peripheral blood (4.2%±1.2 and mesenteric lymph nodes (1.3%±0.8. Regardless of the tissue compartment, CD161+CD8+ T cells mainly comprised of γδ T cells and TCR Vα7.2+ MAIT cells (up to 80%, and displayed Th1 and Th17 cytokine responses to mitogen stimulation. Mucosal CD161+CD8+ T cells were characterized by very high expression of CD69, a recent activation marker that is preferentially expressed on tissue resident cells. Furthermore, lung and colonic mucosal CD161+CD8+ T cells showed enhanced IFN-γ, IL-17, and Perforin production in comparison to those in blood. Thus, macaque CD161+CD8+ T cells represent mucosal tissue-homing innate-like CD8+ T-cell populations with Th1/Th17 type cytokine and cytotoxic effector functions that can potentially enhance the recruitment of adaptive immune cells and control initial pathogen burden/dissemination in tissues. Analysis of their role in early immune responses to mucosal pathogens will be valuable in the design of vaccines and therapeutics.

  17. Estudo histomorfométrico dos cardiomiócitos do ventrículo esquerdo das ratas albinas durante a prenhez Histomorphometrical study of cardiomyocytes of the left ventricular of albino rats during pregnancy

    Directory of Open Access Journals (Sweden)

    A.W. Liberatori Filho

    1999-07-01

    Full Text Available OBJETIVO. No presente estudo propusemo-nos a avaliar, por meio da microscopia de luz, os aspectos morfológicos e morfométricos dos cardiomiócitos do ventrículo esquerdo de ratas albinas durante a prenhez. MÉTODOS. Acasalamos doze ratas virgens que foram dividas ao acaso em quatro grupos, de acordo com a idade gestacional. Os animais correspondentes a cada grupo foram sacrificados ao 1o(G-A, 7o(G-B, 14o(G-C e 21o(G-D dias de prenhez, sendo coletados fragmentos do terço médio do ventrículo esquerdo, os quais após processamento apropriado, permitiram observação adequada à microscopia de luz. A cariometria foi realizada mensurando-se os diâmetros maiores e menores dos cardiomiócitos com o auxílio de um tambor rotativo modelo K 8 X adaptado a um microscópio de luz. RESULTADOS. O estudo em nível da microscopia de luz praticamente não mostrou alterações com o decorrer da prenhez. No entanto, a morfometria revelou que os volumes dos cardiomiócitos estão aumentados no 14o dia da prenhez, mostrando-se estatisticamente significante quando comparado aos demais grupos estudados. Assim, nossos resultados demonstraram haver hipertrofia ventricular esquerda durante a gestação. CONCLUSÃO. Durante a gestação há um processo dinâmico reversível de remodelação ventricular em conseqüência das alterações adaptativas gravídicas.PURPOSE. In the present study we evaluated, by light microscopy, and throughout morphometry, whether hypertrophy of cardiac striated muscular fibers of left ventricular occur in albino rat, during pregnancy. METHODS. After maiting, 12 nuliparous rats were divided into four groups with three animals for each group. The female rats corresponding to each group were killed at 1st, 7th, 14th and 21st days of pregnancy. RESULTS. Observation, on light microscopy (H.E had at one view, did not display any alterations during pregnancy. However, the morphometry revealed that nuclei of cardiomyocytes are augmented in

  18. Energy in India's Future: Insights

    Energy Technology Data Exchange (ETDEWEB)

    Lesourne, J.; Ramsay, W.C.; Jaureguy-Naudin, Maite; Boillot, Jean-Joseph; Autheman, Nicolas; Ruet, Joel; Siddiqui, Zakaria; Zaleski, C. Pierre; Cruciani, Michel

    2009-07-01

    In the decades following India's independence from British rule in 1947, the West's image of India was summarized in three simple cliches: the world's largest democracy, an impoverished continent, and economic growth hampered by a fussy bureaucracy and the caste system, all in a context of a particular religion. These cliches are perhaps one of the reasons that the success of India's green revolution was recognized so late, a revolution that allowed the country to develop its agricultural sector and to feed its population. Since the 1990's, the easing of planning constraints have liberated the Indian economy and allowed it to embark on a more significant path of growth. New cliches have begun to replace the old: India will become a second China and, lagging by 10 to 20 years, will follow the same trajectory, with its development marked more by services and the use of renewable energy. However, these trends will not prevent primary energy demand from exploding. On the contrary, India faces difficult choices on how it increases clean, secure, affordable energy to all its citizens. Many of the choices are the same as found elsewhere, but on a scale matched only by China. The IFRI European Governance and Geopolitics of Energy Project intends this study to deepen public understanding of the magnitude of India's challenges. Various aspects of the serious energy problems are studied throughout this monograph. The authors have written freely on these matters without attempting to reconcile their different viewpoints. The first chapter, by Maite Jaureguy-Naudin and Jacques Lesourne, presents an overview of India's present and future energy system. The authors follow a prudent but realistic view of India's future. The second chapter, by Jean-Joseph Boillot, a French expert on India who has published several books and articles on this subject, and Nicolas Autheman, research fellow, describes in greater detail the specifics of India

  19. Väike teatmik (Tartu paranoiakriitilise risoomi kohta / A Small Guide to the (Tartu Paranoiac-Critical Rhizome

    Directory of Open Access Journals (Sweden)

    Aare Pilv

    2013-06-01

    Full Text Available The paper gives an overview of a network of authors who have been active since the end of the 20th century, mainly (but not only in Tartu. They can be characterized as having an experimental attitude and maintaining distance from the literary mainstream, but at the same time they do not try to be consciously polemical or novatory, because partly they repeat the techniques of the 20th century avant-garde and, what is maybe more important, they sidestep the dialectics of innovating or altering the literary canon. The network is not strictly organized; it is rather a rhizome that has some denser nodes (literary journals and mailing lists. There have been different attempts to name the phenomenon: Tartu avant-garde, microcosmic literature, cognitive realism, Y-literature, "eksp" and so on. I have chosen "paranoiac-critique" as the term that best captures the common characteristics of these authors and their artistic practices (some of the authors are active not only as text writers, but also as conceptual artists.The paper then gives a list, with commentary, of the most important groups and individuals of that movement. In the role of "predecessors" are the group 14NÜ (Paavo Matsin, Mait Laas, Marianne Ravi et al., which also experimented with the format of the book, and a company in Tartu that developed a specific actionist stylistics called "mugiv" (Marko Kompus, Mehis Heinsaar, Martiini, Kaspar et al.. The sovereign figure in the experimental network is Valdur Mikita, who has also academically researched the problems of creativity; he is also a theoretician and metapoet. An important institution for the network has been the literary journal Vihik (initiator Berk Vaher; the later editor of the journal Jaak Tomberg has also participated in activities of the Tartu Theatre Laboratory (managed by Andreas W, which has experimented with "technological theatre". In the middle of the first decade of the 21st century the network has gathered around the

  20. Laps(epõlv 19. sajandi teise poole Eestis omaelulooliste tekstide näitel. Child(hood in 19th Century Estonia: a Study of Autobiographical Texts

    Directory of Open Access Journals (Sweden)

    Ave Mattheus

    2012-04-01

    Full Text Available In this article I discuss autobiographical texts which focus on children and childhood in late 19th century Estonia. Childhood memories as well as other autobiographical material became popular in Estonia in the 1920s-1930s, when most of the studied works--the memoirs by Anna Haava, Mait Metsanurk, Jaan Lattik, Jaan Vahtra, Friedebert Tuglas, August Kitzberg and Marta Sillaots--were written. Some texts come from the 19th century (e.g. Lilli Suburg’s autobiographical works or early 20th century (e.g. manuscripts by Hans Leoke, and Johannes Kõrv. Childhood as described in these autobiographical texts covers a period of circa 1850-1900, and the majority of the authors come from the families of South-Estonian peasants or manorial servants. In addition to being written in Estonian and having the same theme, they were all also written by authors of fiction for children or by people who had close contact with children, such as schoolteachers. The article offers a novel approach in the Estonian context by presenting a typology of childhood stories and looking at childhood recollections as an important part of childhood studies. The researchers of childhood investigate how society understands and values children and childhood, what children’s everyday life is like, what possibilities there are for development and if there exists a specific children’s culture in society (such as clothing, food, language, leisure activities, or independent creative work. Childhood studies as a separate discipline does not exist in Estonia, although some important works have been published by educational scholars and art historians. The autobiographical texts under discussion show that in the late 19th century, the majority of Estonian children lived in the countryside in patriarchal families, and childhood was short because children had to help their parents with farmwork quite early, at the age of six. The boundary of childhood was around the age of 10-11, when