Jaanus Truu : ruumi on ainult nishiärile / Jaanus Truu ; interv. Jaana Pikalev
Truu, Jaanus
2008-01-01
Ilmunud ka: Ilmunud ka: Delovõje Vedomosti : Logistika i Transport 28. mai lk. 6. Ewals Cargo Care OÜ tegevjuht Jaanus Truu vastab küsimustele, mis puudutavad tema seotust logistikaga, senist karjääri ning logistika arengut Eestis ja mujal maailmas. Lisa: Kes on kes
DOE contractor vulnerability analysis: DPA or MAIT
International Nuclear Information System (INIS)
Six, D.E.; Nichols, D.H.
1980-01-01
Two vulnerability analysis techniques, Diversion Path Analysis (DPA) and Matrix Analysis of the Insider Threat (MAIT), were applied by EG and G Idaho, Inc. Safeguards and Security to the same item accountable SNM storage area at INEL. Technical and cost data for each methodology were collected and compared. A recommendation that MAIT be utilized for future vulnerability analyses of item accountable SNM storage and use areas operated by EG and G Idaho for DOE-ID resulted. Unclassified results of the two techniques and MAIT/DPA technical and cost comparisons will be presented which show that MAIT can be used for vulnerability analyses to comply with Department of Energy (DOE) requirements
Stepwise development of MAIT cells in mouse and human.
Directory of Open Access Journals (Sweden)
Emmanuel Martin
2009-03-01
Full Text Available Mucosal-associated invariant T (MAIT cells display two evolutionarily conserved features: an invariant T cell receptor (TCRalpha (iTCRalpha chain and restriction by the nonpolymorphic class Ib major histocompatibility complex (MHC molecule, MHC-related molecule 1 (MR1. MR1 expression on thymus epithelial cells is not necessary for MAIT cell development but their accumulation in the gut requires MR1 expressing B cells and commensal flora. MAIT cell development is poorly known, as these cells have not been found in the thymus so far. Herein, complementary human and mouse experiments using an anti-humanValpha7.2 antibody and MAIT cell-specific iTCRalpha and TCRbeta transgenic mice in different genetic backgrounds show that MAIT cell development is a stepwise process, with an intra-thymic selection followed by peripheral expansion. Mouse MAIT cells are selected in an MR1-dependent manner both in fetal thymic organ culture and in double iTCRalpha and TCRbeta transgenic RAG knockout mice. In the latter mice, MAIT cells do not expand in the periphery unless B cells are added back by adoptive transfer, showing that B cells are not required for the initial thymic selection step but for the peripheral accumulation. In humans, contrary to natural killer T (NKT cells, MAIT cells display a naïve phenotype in the thymus as well as in cord blood where they are in low numbers. After birth, MAIT cells acquire a memory phenotype and expand dramatically, up to 1%-4% of blood T cells. Finally, in contrast with NKT cells, human MAIT cell development is independent of the molecular adaptor SAP. Interestingly, mouse MAIT cells display a naïve phenotype and do not express the ZBTB16 transcription factor, which, in contrast, is expressed by NKT cells and the memory human MAIT cells found in the periphery after birth. In conclusion, MAIT cells are selected by MR1 in the thymus on a non-B non-T hematopoietic cell, and acquire a memory phenotype and expand in the
Mait Laas : see oli intrigeeriv eksperiment / Mait Laas
Laas, Mait, 1970-
2006-01-01
Kinos Sõprus on ekraanil Ida-Euroopa kuue noore režissööri filmiprojekt "Kaotatud ja leitud" ("Lost and Found"), mille seob tervikuks Mait Laasi nukufilm "Gene+Ratio". Režissöör räägib projektist lähemalt
1999-01-01
Arhitektid V. Künnapu ja M. Truu, sisearhitektid I.-E. Schneider, E. Olle ja M. Peri ning kinnisvaraarendaja A. Aavik vastavad küsimustele, millises ülikoolis nad omandaksid eriala, kui nad oleksi praegu tudengid, Eestis saadava hariduse konkurentsivõimelisuse kohta maailmas, mida nad tahaksid praegu enda täiendamiseks õppida?
MAIT cells are activated in acute Dengue virus infection and after in vitro Zika virus infection.
Directory of Open Access Journals (Sweden)
Dominic Paquin-Proulx
2018-01-01
Full Text Available Dengue virus (DENV and Zika virus (ZIKV are members of the Flaviviridae and are predominantly transmitted via mosquito bites. Both viruses are responsible for a growing number of infections in tropical and subtropical regions. DENV infection can cause lethargy with severe morbidity and dengue shock syndrome leading to death in some cases. ZIKV is now linked with Guillain-Barré syndrome and fetal malformations including microcephaly and developmental disorders (congenital Zika syndrome. The protective and pathogenic roles played by the immune response in these infections is unknown. Mucosal-associated invariant T (MAIT cells are a population of innate T cells with potent anti-bacterial activity. MAIT cells have also been postulated to play a role in the immune response to viral infections. In this study, we evaluated MAIT cell frequency, phenotype, and function in samples from subjects with acute and convalescent DENV infection. We found that in acute DENV infection, MAIT cells had elevated co-expression of the activation markers CD38 and HLA-DR and had a poor IFNγ response following bacterial stimulation. Furthermore, we found that MAIT cells can produce IFNγ in response to in vitro infection with ZIKV. This MAIT cell response was independent of MR1, but dependent on IL-12 and IL-18. Our results suggest that MAIT cells may play an important role in the immune response to Flavivirus infections.
Paquin-Proulx, Dominic; Greenspun, Benjamin C; Costa, Emanuela A S; Segurado, Aluisio C; Kallas, Esper G; Nixon, Douglas F; Leal, Fabio E
2017-01-01
HTLV-1 infection is associated with several inflammatory disorders, including the neurodegenerative condition HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). It is unclear why a minority of infected subjects develop HAM/TSP. The cellular immune response has been implicated in the development of inflammatory alterations in these patients; however the pathogenic mechanisms for disease progression remain unclear. Furthermore, HTLV-1-infected individuals have an increase incidence of Mycobacterium tuberculosis (Mtb) infection, suggesting that immunological defect are associated with HTLV-1 infection. Evidence suggests an important role for Mucosal-associated invariant T (MAIT) cells in the early control of Mtb infection. Chronic viral infections like HIV and HCV have been associated with decreased frequency and functionality of MAIT cells. We hypothesized that HTLV-1 infection is associated with similar perturbations in MAIT cells. We investigated MAIT cell frequency, phenotype, and function by flow cytometry in a cohort of 10 asymptomatic and 10 HAM/TSP HTLV-1 infected patients. We found that MAIT cells from HTLV-1-infected subjects were reduced and showed high co-expression of the activation markers CD38 and HLA-DR but normal levels of CCR6 and CD127. MAIT cells had a lower expression of the transcription factor PLZF in HAM/TSP patients. Unlike Tax-specific CD8+T cells, which are hyperfunctional, MAIT cells from HTLV-1-infected subjects had a poor IFNγ response following antigen stimulation. MAIT cell perturbations in HTLV-1 infection were not associated with HTLV-1 proviral load and MAIT cells were not infected by HTLV-1 in vivo. Rather, MAIT cells loss was associated with immune activation. Overall, our results do not support a role for MAIT cells in HAM/TSP pathogenesis but reduced numbers of MAIT cells, together with their poor functionality, could contribute to the increased susceptibility of HTLV-1-infected individuals to other infectious
Directory of Open Access Journals (Sweden)
Dominic Paquin-Proulx
Full Text Available HTLV-1 infection is associated with several inflammatory disorders, including the neurodegenerative condition HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP. It is unclear why a minority of infected subjects develop HAM/TSP. The cellular immune response has been implicated in the development of inflammatory alterations in these patients; however the pathogenic mechanisms for disease progression remain unclear. Furthermore, HTLV-1-infected individuals have an increase incidence of Mycobacterium tuberculosis (Mtb infection, suggesting that immunological defect are associated with HTLV-1 infection. Evidence suggests an important role for Mucosal-associated invariant T (MAIT cells in the early control of Mtb infection. Chronic viral infections like HIV and HCV have been associated with decreased frequency and functionality of MAIT cells. We hypothesized that HTLV-1 infection is associated with similar perturbations in MAIT cells. We investigated MAIT cell frequency, phenotype, and function by flow cytometry in a cohort of 10 asymptomatic and 10 HAM/TSP HTLV-1 infected patients. We found that MAIT cells from HTLV-1-infected subjects were reduced and showed high co-expression of the activation markers CD38 and HLA-DR but normal levels of CCR6 and CD127. MAIT cells had a lower expression of the transcription factor PLZF in HAM/TSP patients. Unlike Tax-specific CD8+T cells, which are hyperfunctional, MAIT cells from HTLV-1-infected subjects had a poor IFNγ response following antigen stimulation. MAIT cell perturbations in HTLV-1 infection were not associated with HTLV-1 proviral load and MAIT cells were not infected by HTLV-1 in vivo. Rather, MAIT cells loss was associated with immune activation. Overall, our results do not support a role for MAIT cells in HAM/TSP pathogenesis but reduced numbers of MAIT cells, together with their poor functionality, could contribute to the increased susceptibility of HTLV-1-infected individuals to
Directory of Open Access Journals (Sweden)
Johanna Maria Eberhard
Full Text Available Mucosal-associated invariant T (MAIT cells are characterized by the combined expression of the semi-invariant T cell receptor (TCR Vα7.2, the lectin receptor CD161, as well as IL-18R, and play an important role in antibacterial host defense of the gut. The current study characterized CD161(+ MAIT and CD161-TCRVα7.2(+ T cell subsets within a large cohort of HIV patients with emphasis on patients with slow disease progression and elite controllers. Mononuclear cells from blood and lymph node samples as well as plasma from 63 patients and 26 healthy donors were analyzed by multicolor flow cytometry and ELISA for IL-18, sCD14 and sCD163. Additionally, MAIT cells were analyzed after in vitro stimulation with different cytokines and/or fixed E.coli. Reduced numbers of CD161(+ MAIT cells during HIV infection were detectable in the blood and lymph nodes of all patient groups, including elite controllers. CD161+ MAIT cell numbers did not recover even after successful antiretroviral treatment. The loss of CD161(+ MAIT cells was correlated with higher levels of MAIT cell activation; an increased frequency of the CD161-TCRVα7.2(+T cell subset in HIV infection was observed. In vitro stimulation of MAIT cells with IL-18 and IL-12, IL-7 and fixed E.coli also resulted in a rapid and additive reduction of the MAIT cell frequency defined by CD161, IL-18R and CCR6. In summary, the irreversible reduction of the CD161(+ MAIT cell subset seems to be an early event in HIV infection that is independent of later stages of the disease. This loss appears to be at least partially due to the distinctive vulnerability of MAIT cells to the pronounced stimulation by microbial products and cytokines during HIV-infection.
DEFF Research Database (Denmark)
Gold, Marielle C.; McLaren, James E.; Reistetter, Joseph A.
2014-01-01
Mucosal-associated invariant T (MAIT) cells express a semi-invariant T cell receptor (TCR) that detects microbial metabolites presented by the nonpolymorphic major histocompatibility complex (MHC)-like molecule MR1. The highly conserved nature of MR1 in conjunction with biased MAIT TCRα chain usa...
DEFF Research Database (Denmark)
Gold, Marielle C.; McLaren, James E.; Reistetter, Joseph A.
2015-01-01
with this interpretation, MAIT cell clones with distinct TCRs responded differentially to a riboflavin metabolite. These results suggest that MAIT cells can discriminate between pathogen-derived ligands in a clonotype-dependent manner, providing a basis for adaptive memory via recruitment of specific repertoires shaped...
Hobusega kiirrongi ei püüa / Mait Klaassen
Klaassen, Mait, 1955-
2002-01-01
Ilmunud ka: Pärnu Postimees, Virumaa Teataja, Sakala, Vooremaa, Põhjarannik, Severnoje Poberezhje, Võrumaa Teataja, Valgamaalane, Koit, Lääne Elu 12. nov. lk. 7;4;4;3;5;5;3;4;3;2. Võru maavanem Mait Klaassen loodab, et liitumisel EL-iga läheb Eestil korda jõuda jõukale järjele ja samas säilitada iseseisvus
MAIT application to the analysis of commercial power plants
International Nuclear Information System (INIS)
Goldman, L.A.; McDaniel, T.L.; Chapman, L.D.; Stack, D.
1981-01-01
This paper discusses a study which was conducted for the U.S. Nuclear Regulatory Commission (NRC) to determine the applicability of the Matrix Analysis of the Insider Threat (MAIT) code to the analysis of sabotage vulnerabilities of commercial power reactors. The sabotage of concern was the initiation of a release of radioactivity in excess of 10 CFR 100 guidelines. 5 refs
Mondot, Stanislas; Boudinot, Pierre; Lantz, Olivier
2016-08-01
MAIT cells express an invariant TCR that recognizes non-peptidic microbial antigens presented by the non-polymorphic MHCI-like molecule, MR1. We briefly describe how the antigens recognized by MAIT cells are generated from an unstable precursor of the riboflavin (Vitamin B2) biosynthesis pathway, as well as the main features of MAIT cells in comparison with other related T cell subsets. In silico analysis of bacterial genomes shows that the riboflavin biosynthesis pathway is highly prevalent in all groups of Prokaryotes with, however, notable exceptions. We discuss the putative functions and the evolution of the MAIT/MR1 couple: it appeared in the ancestors of mammals and is highly conserved across this group, but was independently lost in three orders. We describe the four instances of known invariant TCR and MHC-I-like molecules encountered in Vertebrates. Both T cells bearing semi-invariant TCR and the associated, evolutionarily conserved MHC-I related molecules have been found in mammals or in amphibians, which suggests that other MHC1-like/invariant TCR couples might be present in other classes of Vertebrates to detect generic microbial compounds. This allows us to discuss how the recognition of riboflavin precursor derivatives by the MAIT TCR may be a way to detect invasive microbes in specific organs, and may epitomize other invariant T cell systems across vertebrates.
Märt Agu käib isa Mait Agu jälgedes / Heili Sibrits
Sibrits, Heili, 1977-
2001-01-01
Koreograafi ja tantsupedagoogi Mait Agu poeg Märt Agu on Eesti Tantsuagentuuri tantsija ja Pedagoogilise Instituudi tantsujuhtimise viimase kursuse üliõpilane, kes esineb revüüteatris "Bel-⁹tage"
Mahtra muuseumis ja Juuru vallas käisid auväärsed külalised / Tiia Truu
Truu, Tiia, 1948-
2009-01-01
1. juulil 2009 külastasid Mahtra talurahvamuuseumi Mahtra sõja mälestusmärgi looja Johannes Tuti lesk Leili Tutt ja nende poeg Mait Tutt Rootsist ning tütar Eha Dascenzo USA-st Swanscast, nendega koos oli J. Tuti vennatütar Maie Vikat
Taifuun nimega Valimised on möödas / Mait Klaassen
Klaassen, Mait, 1955-
2005-01-01
Ilmunud ka: Põhjarannik 20. okt., lk. 2, Severnoje Poberezhje 20. okt., lk. 2, Meie Maa 20. okt., lk. 2, Sakala 21. okt., lk. 2, Vali Uudised 21. okt. lk. 2, Koit, Järva Teataja 22. okt. lk. 6,2, Lääne Elu 25. okt., lk. 2, Harjumaa 25. okt. lk. 2, Vooremaa 27. okt. lk. 2. Parlamendisaadik, Reformierakonna liige Mait Klaassen teeb kokkuvõtte lõppenud kohalikest valimistest
DEFF Research Database (Denmark)
Wong, E. B.; Xulu, B.; Prakadan, S.
2016-01-01
Tuberculosis remains the leading cause of death in HIV-positive people. A better understanding of the impact of HIV on lung immunity may lead to novel immunotherapeutic interventions. MAIT cells are tissue-homing donor-unrestricted T cells with broad anti-microbial activity. HIV infection causes ...... to determine the mechanisms underlying the altered phenotypes of lung-resident MAITs and whether these can be targeted to improve anti-microbial lung immunity in people living with HIV....
Directory of Open Access Journals (Sweden)
Christopher R Shaler
2017-06-01
Full Text Available Superantigens (SAgs are potent exotoxins secreted by Staphylococcus aureus and Streptococcus pyogenes. They target a large fraction of T cell pools to set in motion a "cytokine storm" with severe and sometimes life-threatening consequences typically encountered in toxic shock syndrome (TSS. Given the rapidity with which TSS develops, designing timely and truly targeted therapies for this syndrome requires identification of key mediators of the cytokine storm's initial wave. Equally important, early host responses to SAgs can be accompanied or followed by a state of immunosuppression, which in turn jeopardizes the host's ability to combat and clear infections. Unlike in mouse models, the mechanisms underlying SAg-associated immunosuppression in humans are ill-defined. In this work, we have identified a population of innate-like T cells, called mucosa-associated invariant T (MAIT cells, as the most powerful source of pro-inflammatory cytokines after exposure to SAgs. We have utilized primary human peripheral blood and hepatic mononuclear cells, mouse MAIT hybridoma lines, HLA-DR4-transgenic mice, MAIThighHLA-DR4+ bone marrow chimeras, and humanized NOD-scid IL-2Rγnull mice to demonstrate for the first time that: i mouse and human MAIT cells are hyperresponsive to SAgs, typified by staphylococcal enterotoxin B (SEB; ii the human MAIT cell response to SEB is rapid and far greater in magnitude than that launched by unfractionated conventional T, invariant natural killer T (iNKT or γδ T cells, and is characterized by production of interferon (IFN-γ, tumor necrosis factor (TNF-α and interleukin (IL-2, but not IL-17A; iii high-affinity MHC class II interaction with SAgs, but not MHC-related protein 1 (MR1 participation, is required for MAIT cell activation; iv MAIT cell responses to SEB can occur in a T cell receptor (TCR Vβ-specific manner but are largely contributed by IL-12 and IL-18; v as MAIT cells are primed by SAgs, they also begin to
Isepäine modernist Toomas Rein / Toomas Rein ; intervjueerinud Mait Väljas ja Reet Varblane
Rein, Toomas, 1940-
2010-01-01
23. aprillil avatakse Eesti Arhitektuurimuuseumis arhitekt Toomas Reinu 70. sünnipäevale pühendatud näitus. Kataloogi ja näituse on koostanud Toomas Rein ja Mait Väljas, kujundanud Tiit Jürna. Toomas Rein endast, oma loomingust, eeskujudest, näitusest, nõukogude perioodi hoonete olukorrast, viimase aja töödest, koostööst teiste arhitektidega, teostamata projektidest
Held, Kathrin; Beltrán, Eduardo; Moser, Markus; Hohlfeld, Reinhard; Dornmair, Klaus
2015-09-01
Mucosal-associated invariant T (MAIT) cells are a T-cell subset that expresses a conserved TRAV1-2 (Vα7.2) T-cell receptor (TCR) chain and the surface marker CD161. They are involved in the defence against microbes as they recognise small organic molecules of microbial origin that are presented by the non-classical MHC molecule 1 (MR1). MAIT cells express a semi-restricted TCR α chain with TRAV1-2 preferentially linked to TRAJ33, TRAJ12, or TRAJ20 which pairs with a limited set of β chains. To investigate the TCR repertoire of human CD161(hi)TRAV1-2(+) T cells in depth we analysed the α and β chains of this T-cell subset by next generation sequencing. Concomitantly we analysed 132 paired α and β chains from single cells to assess the αβ pairing preferences. We found that the CD161(hi)TRAV1-2(+) TCR repertoire in addition to the typical MAIT TCRs further contains polyclonal elements reminiscent of classical αβ T cells. Copyright © 2015 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.
Raava, Mait
2006-01-01
Pro Konsultatsioonide juhtimiskonsultant Mait Raava, Bank Saint Petersburgi nõukogu esimees Indrek Neivelt, Euroopa Komisjoni innovatsiooni ja väikeettevõtluse üksuse direktor Maive Rute vastavad küsimustele, mis puudutavad Eesti juhtide mainet ning töötamist välisriikides
Tähed disainiöös / Mait Summatavet, Risto Räägel, Per Mollerup...[jt.] ; interv. Karin Paulus
2007-01-01
Disainiöö raames avati Arhitektuuri- ja Disainigaleriis näitus "Kokkupandavad asjad" ning kuulutati välja konkursi võitjad. Peapreemia võitis läti disaineri Elina Bushmane kokkupandav teelaud, teise koha Jaana Päeva tekstiilist kott, kolmanda koha Ingrem Floreni käekott. Ära märgiti Veiko Liisi kilepiima vutlar. Disainiöö üritustest ning konkursitöödest räägivad Mait Summatavet, Per Mollerup, Simo Heikkilä, Risto Räägel
Kwon, Yong-Soo; Cho, Young-Nan; Kim, Moon-Ju; Jin, Hye-Mi; Jung, Hyun-Ju; Kang, Jeong-Hwa; Park, Ki-Jeong; Kim, Tae-Jong; Kee, Hae Jin; Kim, Nacksung; Kee, Seung-Jung; Park, Yong-Wook
2015-05-01
Mucosal-associated invariant T (MAIT) cells contribute to protection against certain microorganism infections. The aims of this study were to examine the levels of MAIT cells in pulmonary tuberculosis (TB) and nontuberculous mycobacteria (NTM) lung disease patients, to evaluate the clinical relevance of MAIT cell levels, and to investigate the functions of MAIT cells. Patients with pulmonary TB (n = 35), NTM (n = 29), and healthy controls (n = 75) were enrolled in the study. MAIT cell levels and functions were measured by flow cytometry. Circluating MAIT cell levels were found to be reduced in TB and NTM patients. MAIT cell deficiency reflects a variety of clinical conditions. In particular, MAIT cell numbers were significantly correlated with sputum AFB positivity, extent of disease, hemoglobin levels, lymphocyte counts, CRP and ESR levels. MAIT cells in TB patients failed to produce interferon-γ irrespective of the mode of stimulation, whereas NTM patients displayed a defect in MR1-dependent signaling pathway. Notably, an elevated expression of programmed death-1 was also associated with MAIT cell deficiency in TB. This study shows that MAIT cells are numerically and functionally deficient in TB and NTM patients and these deficiencies could contribute to immune system dysreguation in mycobacterial infection. Copyright © 2015 Elsevier Ltd. All rights reserved.
Kang, Seung-Ji; Jin, Hye-Mi; Won, Eun Jeong; Cho, Young-Nan; Jung, Hyun-Ju; Kwon, Yong-Soo; Kee, Hae Jin; Ju, Jae Kyun; Kim, Jung-Chul; Kim, Uh Jin; Jang, Hee-Chang; Jung, Sook-In; Kee, Seung-Jung; Park, Yong-Wook
2016-07-01
Mucosal-associated invariant T (MAIT) cells contribute to protection against certain microorganism infections. However, little is known about the role of MAIT cells in Orientia tsutsugamushi infection. Hence, the aims of this study were to examine the level and function of MAIT cells in patients with scrub typhus and to evaluate the clinical relevance of MAIT cell levels. Thirty-eight patients with scrub typhus and 53 health control subjects were enrolled in the study. The patients were further divided into subgroups according to disease severity. MAIT cell level and function in the peripheral blood were measured by flow cytometry. Circulating MAIT cell levels were found to be significantly reduced in scrub typhus patients. MAIT cell deficiency reflects a variety of clinical conditions. In particular, MAT cell levels reflect disease severity. MAIT cells in scrub typhus patients displayed impaired tumor necrosis factor (TNF)-α production, which was restored during the remission phase. In addition, the impaired production of TNF-α by MAIT cells was associated with elevated CD69 expression. This study shows that circulating MAIT cells are activated, numerically deficient, and functionally impaired in TNF-α production in patients with scrub typhus. These abnormalities possibly contribute to immune system dysregulation in scrub typhus infection.
Hanson, Erik D; Danson, Eli; Nguyen-Robertson, Catriona V; Fyfe, Jackson J; Stepto, Nigel K; Bartlett, David B; Sakkal, Samy
2017-11-01
Mucosal associated invariant T (MAIT) cells have properties of the innate and acquired immune systems. While the response to vigorous exercise has been established for most leukocytes, MAIT cells have not been investigated. Therefore, the purpose was to determine if MAIT cell lymphocytosis occurs with acute maximal aerobic exercise and if this response is influenced by exercise duration, cardiovascular fitness, or body composition. Twenty healthy young males with moderate fitness levels performed an extended graded exercise test until volitional fatigue. Peripheral blood mononuclear cells were isolated from venous blood obtained prior and immediately after exercise and were labeled to identify specific T cell populations using flow cytometry. The percentage of MAIT cells relative to total T cells significantly increased from 3.0 to 3.8% and absolute MAIT cell counts increased by 2.2-fold following maximal exercise. MAIT cell subpopulation proportions were unchanged with exercise. Within cytotoxic T lymphocytes (CTL), MAIT cells consisted of 8% of these cells and this remained constant after exercise. MAIT cell counts and changes with exercise were not affected by body composition, VO 2peak , or exercise duration. Maximal exercise doubled MAIT cell numbers and showed preferential mobilization within total T cells but the response was not influenced by fitness levels, exercise duration, or body composition. These results suggest that acute exercise could be used to offset MAIT cell deficiencies observed with certain pathologies. MAIT cells also make up a substantial proportion of CTLs, which may have implications for cytotoxicity assays using these cells.
Directory of Open Access Journals (Sweden)
Yean K. Yong
2018-03-01
Full Text Available Mucosal-associated invariant T (MAIT cells, defined as CD161++TCR iVα7.2+ T cells, play an important role in the innate defense against bacterial infections, and their functionality is impaired in chronic viral infections. Here, we investigated the frequency and functional role of MAIT cells in chronic hepatitis B virus (HBV infection. The peripheral CD3+CD161++TCR iVα7.2+ MAIT cells in chronic HBV-infected patients and healthy controls were phenotypically characterized based on CD57, PD-1, TIM-3, and CTLA-4, as well as HLA-DR and CD38 expression. The frequency of MAIT cells was significantly decreased among chronic HBV-infected individuals as compared to controls. Expression of CD57, PD-1, CTLA-4, as well as HLA-DR and CD38 on MAIT cells was significantly elevated in chronic HBV-infected individuals relative to controls. The percentage of T cell receptor (TCR iVα7.2+ CD161+ MAIT cells did not correlate with HBV viral load but inversely with HLA-DR on CD4+ T cells and MAIT cells and with CD57 on CD8+ T cells suggesting that decrease of MAIT cells may not be attributed to direct infection by HBV but driven by HBV-induced chronic immune activation. The percentage and expression levels of PD-1 as well as CTLA-4 on MAIT cells inversely correlated with plasma HBV-DNA levels, which may suggest either a role for MAIT cells in the control of HBV infection or the effect of HBV replication in the liver on MAIT cell phenotype. We report that decrease of TCR iVα7.2+ MAIT cells in the peripheral blood and their functions were seemingly impaired in chronic HBV-infected patients likely because of the increased expression of PD-1.
Kesklinna politseihoone = The Central Tallinn Police Department / Margit Mutso
Mutso, Margit, 1966-
2010-01-01
Tallinnas Kolde pst. 65 asuva Kesklinna politseihoone arhitektuursest lahendusest. Arhitekt, sisearhitekt Meeli Truu, kaasautor Gersti Siimon (AS Nord Projekt). Žürii liikme Kalle Komissarovi hinnang kultuurkapitali aastapreemiale esitatud hoonele
Wannabe - Ameerika ja Postkontor 2 / Karin Paulus
Paulus, Karin, 1975-
2008-01-01
Uued hotellid Tallinna kesklinnas: Kaksiktornid (arhitektuuribüroo Nord Projekt, Meeli Truu, sisekujundaja Meelis Press); Forumi hotell (arhitektuuribüroo Pluss, Indrek Allmann, sisekujundajad Kaire Kemp-Tishler ja Ea Andla)
Restoran Cha Dao = Restaurant Cha Dao
2012-01-01
Tallinnas Suur-Patarei 2 asuva Hiina restorani Cha Dao sisekujundusest. Restorani mööbel, v.a toolid, projekteeriti eritellimusena. Sisearhitekt Dmitri Pisarenko (DM3 OÜ), loetletud tema töid. Arhitekt Meeli Truu
Jänes, Liina, 1977-
2000-01-01
Eesti kolhoosikeskuste arhitektuurist. Vaadeldakse aastail 1957-1990 ehitatud 24 keskusehoonet. Arhitektid Nikolai Kusmin, Harri Kingo, Toomas Rein, Vilen Künnapu, Ain Padrik, Maara Metsal, Meeli Truu jt. 17 välisvaadet, 3 joon., kaart
Vedurimehed võivad rongiliikluse kolmeks päevaks seisata / Matis Song
Song, Matis, 1978-
2004-01-01
Ametiühing nõuab vedurimeestele 15-protsendilist palgatõusu tagasiulatuvalt selle aasta 1. märtsist, kusjuures peab säilima kehtiv töötasustamise süsteem. Vt. samas: Tiia Truu. Nõudmised ei ole ebaõiglased
Directory of Open Access Journals (Sweden)
Yutaka Saito
Full Text Available Mucosal-associated invariant T cells (MAITs are innate-like T cells that play a pivotal role in the host defense against infectious diseases, and are also implicated in autoimmune diseases, metabolic diseases, and cancer. Recent studies have shown that induced pluripotent stem cells (iPSCs derived from MAITs selectively redifferentiate into MAITs without altering their antigen specificity. Such a selective differentiation is a prerequisite for the use of MAITs in cell therapy and/or regenerative medicine. However, the molecular mechanisms underlying this phenomenon remain unclear. Here, we performed methylome and transcriptome analyses of MAITs during the course of differentiation from iPSCs. Our multi-omics analyses revealed that recombination-activating genes (RAG1 and RAG2 and DNA nucleotidylexotransferase (DNTT were highly methylated with their expression being repressed throughout differentiation. Since these genes are essential for V(DJ recombination of the T cell receptor (TCR locus, this indicates that nascent MAITs are kept from further rearrangement that may alter their antigen specificity. Importantly, we found that the repression of RAGs was assured in two layers: one by the modulation of transcription factors for RAGs, and the other by DNA methylation at the RAG loci. Together, our study provides a possible explanation for the unaltered antigen specificity in the selective differentiation of MAITs from iPSCs.
Mucosal-Associated Invariant T Cells: New Insights into Antigen Recognition and Activation
Directory of Open Access Journals (Sweden)
Xingxing Xiao
2017-11-01
Full Text Available Mucosal-associated invariant T (MAIT cells, a novel subpopulation of innate-like T cells that express an invariant T cell receptor (TCRα chain and a diverse TCRβ chain, can recognize a distinct set of small molecules, vitamin B metabolites, derived from some bacteria, fungi but not viruses, in the context of an evolutionarily conserved major histocompatibility complex-related molecule 1 (MR1. This implies that MAIT cells may play unique and important roles in host immunity. Although viral antigens are not recognized by this limited TCR repertoire, MAIT cells are known to be activated in a TCR-independent mechanism during some viral infections, such as hepatitis C virus and influenza virus. In this article, we will review recent works in MAIT cell antigen recognition, activation and the role MAIT cells may play in the process of bacterial and viral infections and pathogenesis of non-infectious diseases.
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Liana Ghazarian
2017-12-01
Full Text Available Mucosal-associated invariant T (MAIT cells are unconventional CD3+CD161high T lymphocytes that recognize vitamin B2 (riboflavin biosynthesis precursor derivatives presented by the MHC-I related protein, MR1. In humans, their T cell receptor is composed of a Vα7.2-Jα33/20/12 chain, combined with a restricted set of Vβ chains. MAIT cells are very abundant in the liver (up to 40% of resident T cells and in mucosal tissues, such as the lung and gut. In adult peripheral blood, they represent up to 10% of circulating T cells, whereas they are very few in cord blood. This large number of MAIT cells in the adult likely results from their gradual expansion with age following repeated encounters with riboflavin-producing microbes. Upon recognition of MR1 ligands, MAIT cells have the capacity to rapidly eliminate bacterially infected cells through the production of inflammatory cytokines (IFNγ, TNFα, and IL-17 and cytotoxic effector molecules (perforin and granzyme B. Thus, MAIT cells may play a crucial role in antimicrobial defense, in particular at mucosal sites. In addition, MAIT cells have been implicated in diseases of non-microbial etiology, including autoimmunity and other inflammatory diseases. Although their participation in various clinical settings has received increased attention in adults, data in children are scarce. Due to their innate-like characteristics, MAIT cells might be particularly important to control microbial infections in the young age, when long-term protective adaptive immunity is not fully developed. Herein, we review the data showing how MAIT cells may control microbial infections and how they discriminate pathogens from commensals, with a focus on models relevant for childhood infections.
Mucosa-associated invariant T cells in malignancies: a faithful friend or formidable foe?
Haeryfar, S M Mansour; Shaler, Christopher R; Rudak, Patrick T
2018-02-22
Mucosa-associated invariant T (MAIT) cells are a subset of innate-like T lymphocytes known for their ability to respond to MHC-related protein 1 (MR1)-restricted stimuli and select cytokine signals. They are abundant in humans and especially enriched in mucosal layers, common sites of neoplastic transformation. MAIT cells have been found within primary and metastatic tumors. However, whether they promote malignancy or contribute to anticancer immunity is unclear. On the one hand, MAIT cells produce IL-17A in certain locations and under certain circumstances, which could in turn facilitate neoangiogenesis, intratumoral accumulation of immunosuppressive cell populations, and cancer progression. On the other hand, they can express a potent arsenal of cytotoxic effector molecules, NKG2D and IFN-γ, all of which have established roles in cancer immune surveillance. In this review, we highlight MAIT cells' characteristics as they might pertain to cancer initiation, progression, or control. We discuss recent findings, including our own, that link MAIT cells to cancer, with a focus on colorectal carcinoma, as well as some of the outstanding questions in this active area of research. Finally, we provide a hypothetical picture in which MAIT cells constitute attractive targets in cancer immunotherapy.
Bolte, Fabian J; O'Keefe, Ashley C; Webb, Lauren M; Serti, Elisavet; Rivera, Elenita; Liang, T Jake; Ghany, Marc; Rehermann, Barbara
2017-11-01
Chronic hepatitis affects phenotypes of innate and adaptive immune cells. Mucosal-associated invariant T (MAIT) cells are enriched in the liver as compared with the blood, respond to intra-hepatic cytokines, and (via the semi-invariant T-cell receptor) to bacteria translocated from the gut. Little is known about the role of MAIT cells in livers of patients with chronic hepatitis C virus (HCV) infection and their fate after antiviral therapy. We collected blood samples from 42 patients with chronic HCV infection who achieved a sustained virologic response after 12 weeks of treatment with sofosbuvir and velpatasvir. Mononuclear cells were isolated from blood before treatment, at weeks 4 and 12 during treatment, and 24 weeks after the end of treatment. Liver biopsies were collected from 37 of the patients prior to and at week 4 of treatment. Mononuclear cells from 56 blood donors and 10 livers that were not suitable for transplantation were used as controls. Liver samples were assessed histologically for inflammation and fibrosis. Mononuclear cells from liver and blood were studied by flow cytometry and analyzed for responses to cytokine and bacterial stimulation. The frequency of MAIT cells among T cells was significantly lower in blood and liver samples of patients with HCV infection than of controls (median, 1.31% vs 2.32% for blood samples, P = .0048; and median, 4.34% vs 13.40% for liver samples, P = .001). There was an inverse correlation between the frequency of MAIT cells in the liver and histologically determined levels of liver inflammation (r = -.5437, P = .0006) and fibrosis (r = -.5829, P = .0002). MAIT cells from the liver had higher levels of activation and cytotoxicity than MAIT cells from blood (P liver inflammation and MAIT cell activation and cytotoxicity, and increased the MAIT cell frequency among intra-hepatic but not blood T cells. The MAIT cell response to T-cell receptor-mediated stimulation did not change during the 12 weeks of
Armastus on teinud jälle imet / Virve Liivanõmm
Liivanõmm, Virve
2011-01-01
Tallinna Linnamäe vene lütseumist, õpetaja Alla Belenkovast ja tema kirjutatud baltlastest lütseistidele pühendatud monograafiast "Святому братству верен я" ("Pühale vennaskonnale olen truu", kirjastus SE&JS)
Mida loodavad poliitikud? / Urmas Lauri
Lauri, Urmas, 1956-
1998-01-01
Vastavad T. Jürgenson, S. Ivanov, A. Rüütel, A. Haug, O. Anton, Pärnoja, M. Kubo, S. Kallas, K. Kilvet, M. Treial, E. Truu. Järgneb 20. jaan. 1998, lk. 2; 22. jaan. 1998, lk. 2; 27. jaan. 1998, lk. 2. Ilmunud ka: Hiiu Leht, 20. jaan. 1998, lk. 3
Saku Suurhall Rocca al Mares = Saku Suurhall in Rocca al Mare / Inga Raukas
Raukas, Inga, 1967-
2001-01-01
Peaprojekteerija, detailplaneering: Nord Projekt AS. Arhitektid Esa Viitanen (Soome), Andres Kariste, kaastöö: Meeli Truu, Loomet Raudsepp. Sisekujundus: Eero Jürgenson, Maarja Valk-Falk, Tambet Pedak, ARS Interjöörprojekt. Konstruktsioonid: Kaido Kuusiku, Tiit Arumäe, Aive Sau, Jaan Port. Projekteerimise projektijuht Andres Mikker. Projekt 1999-2001, valmis 2001. 9 ill
Ühe novelli lugu : subjektiivne kirjanduslooline etüüd / Aivar Kull
Kull, Aivar, 1955-
2015-01-01
Mait Metsanurga pikemast novellist "Dora Praats", mis ilmus 1943. a. vene keeles; avaldatud ka 16-osalise järjejutuna Toronto ajalehes "Vaba Eestlane" (8. veebr. - 2. aprill 1958) ning Mait Metsanurga novellikogumikus "Kreeps" (Tallinn : Eesti Raamat, 2005)
Reflections on 35 years with Applied Optics: outgoing editorial.
Mait, Joseph N
2014-10-20
Applied Optics' Editor-in-Chief, Joseph N. Mait reflects on his experience as a reader, author, reviewer and eventual editor of the journal. Dr. Mait also introduces the incoming Editor-in-Chief, Ronald G. Driggers and acknowledges outgoing Division Editor, T.-C. Poon.
Mõõdulindiga õnne ja edu kallal / Anneli Aasmäe
Aasmäe, Anneli, 1973-
2000-01-01
Juhtimiskonsultant Mait Raava kinnitusel on edukus 70 protsenti kaasasündinud omadus, Eesti edukatel on tegutsemisvajadus veres, nad võivad toetuda Iisraeli päritolu juhtimisteoreetiku Eliyahu M. Goldratti õpetusele, mitte eduretsepte ja õnnevalemeid pakkuvaile autorite rivile Dale Carnegie'st Ben Furmanini. Kommentaarid: Aune Past, Mait Raava
25 kaadrit sekundis / Liis Auväärt
Auväärt, Liis
2009-01-01
Nukufilmis käib töö filmiga "Lisa Limone & Maroc Orange", režissöör Mait Laas, animaatorid Triin Sarapik-Kivi, Märt Kivi, operaator Ragnar Neljandi, nukumeistrid Heigo Eeriksoo, Taivo Müürsep, Ene Mellow ja Kreeta Käeri. Dekoratsioonimeistrid Mait Erik ja Roman Kuznetsov
Märt Agu: "Isa vari käib mul kogu aeg kannul" / Märt Agu ; interv. Aigi Viira
Agu, Märt
2006-01-01
1. okt. tähistas oma 30-aastast sünnipäeva ja oma ellukutsuja Mait Agu 55-sünniaastapäeva Tallinna Ülikooli koreograafiaosakond. Sel puhul esitati Estonias Mait Agu tantsulavastus "Kodalased ja kaasaegsed", mille seadis uuesti lavale Märt Agu oma isa loodud koreograafia põhjal
Truu armastuse võimalikkusest / Jaan Ruus
Ruus, Jaan, 1938-2017
2005-01-01
Mängufilm "Madisoni maakonna sillad" ("The Bridges of Madison County") : stsenarist Robert James Walleri romaani põhjal Richard LaGravenese : režissöör ja peaosatäitja Clint Eastwood : Ameerika Ühendriigid 1995
Tallinna teekond mereni / Triin Ojari
Ojari, Triin, 1974-
2006-01-01
Tallinna sadamaala arendamise ajaloost 1990-ndatel aastatel ja 21. sajandi algul. Eraldi projektidest: Kalasadama ümbruse planeering (M. Truu, A. Andres, Nord Projekt, 2000-2006), elamukvartal Logi t. 8, 10 (M. Aunin, M. Melioranski, I. Melioranski, 2005), sadamaala detailplaneeringu eskiis (Tallinna Linnaplaneerimise Amet, 2005), hotell-konverentsikeskus-spaa (Ü. Mark, I. Tiigi, Urban Mark), Admiraliteedi kvartali planeeringu eskiis (Chapman Taylor, London, K-Projekt), Holiday City Tallinn (Evata, Soome), hotell "Merikaru" (M. Schuurman), Lootsi kvartali planeeringu ideeprojekt (Kosmos)
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Nicholas M. Provine
2018-04-01
Full Text Available Mucosal-associated invariant T (MAIT cells are innate-like T cells abundant in humans that can be activated in a TCR-independent manner by inflammatory and antiviral cytokines. In humans, the capacity for TCR-independent activation is functionally linked to a transcriptional program that can be identified by the expression of the C-type lectin receptor, CD161. In addition to MAIT cells, it has been demonstrated that a subset of γδT cells expresses CD161 and can be activated by TCR-independent cytokine stimulation. In this study, we sought to clarify the nature of cytokine-responsive human γδT cells. We could link CD161 expression on Vδ2+ versus Vδ1+ γδT cells to the observation that Vδ2+ γδT cells, but not Vδ1+ γδT cells, robustly produced IFN-γ upon stimulation with a variety of cytokine combinations. Interestingly, both CD161+ and CD161− Vδ2+ γδT cells responded to these stimuli, with increased functionality within the CD161+ subset. This innate-like responsiveness corresponded to high expression of PLZF and IL-18Rα, analogous to MAIT cells. Vδ2+ γδT cells in human duodenum and liver maintained a CD161+ IL-18Rα+ phenotype and produced IFN-γ in response to IL-12 and IL-18 stimulation. In contrast to MAIT cells, we could not detect IL-17A production but observed higher steady-state expression of Granzyme B by Vδ2+ γδT cells. Finally, we investigated the frequency and functionality of γδT cells in the context of chronic hepatitis C virus infection, as MAIT cells are reduced in frequency in this disease. By contrast, Vδ2+ γδT cells were maintained in frequency and displayed unimpaired IFN-γ production in response to cytokine stimulation. In sum, human Vδ2+ γδT cells are a functionally distinct population of cytokine-responsive innate-like T cells that is abundant in blood and tissues with similarities to human MAIT cells.
Salerno-Goncalves, Ros?ngela; Luo, David; Fresnay, Stephanie; Magder, Laurence; Darton, Thomas C.; Jones, Claire; Waddington, Claire S.; Blohmke, Christoph J.; Angus, Brian; Levine, Myron M.; Pollard, Andrew J.; Sztein, Marcelo B.
2017-01-01
Gastrointestinal infections by Salmonella enterica serovar Typhi (S. Typhi) are rare in industrialized countries. However, they remain a major public health problem in the developing world with an estimated 26.9 million new cases annually and significant mortality when untreated. Recently, we provided the first direct evidence that CD8(+) MAIT cells are activated and have the potential to kill cells exposed to S. Typhi, and that these responses are dependent on bacterial load. However, MAIT c...
Ishimori, Ayako; Harada, Norihiro; Chiba, Asako; Harada, Sonoko; Matsuno, Kei; Makino, Fumihiko; Ito, Jun; Ohta, Shoichiro; Ono, Junya; Atsuta, Ryo; Izuhara, Kenji; Takahashi, Kazuhisa; Miyake, Sachiko
2017-04-01
A variety of innate subsets of lymphoid cells such as natural killer (NK) cells, several populations of innate lymphoid cells (ILCs), and mucosal-associated invariant T (MAIT) cells as innate-like T lymphocytes are involved in asthma and may have important effector functions in asthmatic immune responses. In the present study, we investigated whether NK cells, ILCs, and MAIT cells in the peripheral blood of patients with asthma would be associated with clinical asthma parameters. We recruited 75 adult patients with mild to severe asthma. The peripheral blood mononuclear cells in peripheral venous blood samples from the patients were purified and stained with different combinations of appropriate antibodies. The cells were analyzed by flow cytometry. The percentage of activated (i.e., CD69 + ) NK cells in the total NK cell population was negatively correlated with FEV 1 % which is calculated by the forced expiratory volume in 1 s (FEV 1 )/the forced vital capacity (FVC). The percentages of CD69 + ILC1s and ILC2s were negatively correlated with FEV 1 % and %FEV 1 . The percentage of CD69 + ILC3s was positively correlated with BMI, and the percentage of CD69 + MAIT cells was negatively correlated with FEV 1 %. Moreover, the percentage of CD69 + NK cells, ILC1s, ILC2s, ILC3s, and MAIT cells were positively correlated with each other. For the first time, our data showed that activated NK cells, ILC1s, ILC2s, ILC3s, and MAIT cells were positively correlated with each other and may be associated with airflow limitation in patients with asthma. Copyright © 2016 Japanese Society of Allergology. Production and hosting by Elsevier B.V. All rights reserved.
Eelrand, Mait, 1950-
2006-01-01
Uutest heliplaatidest JJ CAle & Eric Clapton "The Road To escondido", Fergie "The Dutchess", Cosmoskva "Juniper", "The Devil Wears Prada", Peaches "Impeach My Bush", Ludacris "Release Therapy", Milburn "Well Well Well"
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Chie Sugimoto
Full Text Available Fibromyalgia (FM is defined as a widely distributed pain. While many rheumatologists and pain physicians have considered it to be a pain disorder, psychiatry, psychology, and general medicine have deemed it to be a syndrome (FMS or psychosomatic disorder. The lack of concrete structural and/or pathological evidence has made patients suffer prejudice that FMS is a medically unexplained symptom, implying inauthenticity. Furthermore, FMS often exhibits comorbidity with rheumatoid arthritis (RA or spondyloarthritis (SpA, both of which show similar indications. In this study, disease specific biomarkers were sought in blood samples from patients to facilitate objective diagnoses of FMS, and distinguish it from RA and SpA.Peripheral blood mononuclear cells (PBMCs from patients and healthy donors (HD were subjected to multicolor flow cytometric analysis. The percentage of mucosal-associated invariant T (MAIT cells in PBMCs and the mean fluorescent intensity (MFI of cell surface antigen expression in MAIT cells were analyzed.There was a decrease in the MAIT cell population in FMS, RA, and SpA compared with HD. Among the cell surface antigens in MAIT cells, three chemokine receptors, CCR4, CCR7, and CXCR1, a natural killer (NK receptor, NKp80, a signaling lymphocyte associated molecule (SLAM family, CD150, a degrunulation marker, CD107a, and a coreceptor, CD8β emerged as potential biomarkers for FMS to distinguish from HD. Additionally, a memory marker, CD44 and an inflammatory chemokine receptor, CXCR1 appeared possible markers for RA, while a homeostatic chemokine receptor, CXCR4 deserved for SpA to differentiate from FMS. Furthermore, the drug treatment interruption resulted in alternation of the expression of CCR4, CCR5, CXCR4, CD27, CD28, inducible costimulatory molecule (ICOS, CD127 (IL-7 receptor α, CD94, NKp80, an activation marker, CD69, an integrin family member, CD49d, and a dipeptidase, CD26, in FMS.Combined with the currently available
Sugimoto, Chie; Konno, Takahiko; Wakao, Rika; Fujita, Hiroko; Fujita, Hiroyoshi; Wakao, Hiroshi
2015-01-01
Fibromyalgia (FM) is defined as a widely distributed pain. While many rheumatologists and pain physicians have considered it to be a pain disorder, psychiatry, psychology, and general medicine have deemed it to be a syndrome (FMS) or psychosomatic disorder. The lack of concrete structural and/or pathological evidence has made patients suffer prejudice that FMS is a medically unexplained symptom, implying inauthenticity. Furthermore, FMS often exhibits comorbidity with rheumatoid arthritis (RA) or spondyloarthritis (SpA), both of which show similar indications. In this study, disease specific biomarkers were sought in blood samples from patients to facilitate objective diagnoses of FMS, and distinguish it from RA and SpA. Peripheral blood mononuclear cells (PBMCs) from patients and healthy donors (HD) were subjected to multicolor flow cytometric analysis. The percentage of mucosal-associated invariant T (MAIT) cells in PBMCs and the mean fluorescent intensity (MFI) of cell surface antigen expression in MAIT cells were analyzed. There was a decrease in the MAIT cell population in FMS, RA, and SpA compared with HD. Among the cell surface antigens in MAIT cells, three chemokine receptors, CCR4, CCR7, and CXCR1, a natural killer (NK) receptor, NKp80, a signaling lymphocyte associated molecule (SLAM) family, CD150, a degrunulation marker, CD107a, and a coreceptor, CD8β emerged as potential biomarkers for FMS to distinguish from HD. Additionally, a memory marker, CD44 and an inflammatory chemokine receptor, CXCR1 appeared possible markers for RA, while a homeostatic chemokine receptor, CXCR4 deserved for SpA to differentiate from FMS. Furthermore, the drug treatment interruption resulted in alternation of the expression of CCR4, CCR5, CXCR4, CD27, CD28, inducible costimulatory molecule (ICOS), CD127 (IL-7 receptor α), CD94, NKp80, an activation marker, CD69, an integrin family member, CD49d, and a dipeptidase, CD26, in FMS. Combined with the currently available
Tõeline arhitektuur kolis linnast Juuru valda / Tiia Truu
Truu, Tiia, 1948-
2005-01-01
Arhitektuurivõistlusest, mille eesmärgiks oli saada parim lahendus Mahtra muuseumi laiendamiseks. Esimene preemia - märgusõna "Heinamaa", Tomomi Hayashi ja Hanno Grossschmidt arhitektuuribüroost HG Arhitektuur. Teine preemia - märgusõna "Talgud", Andres Lember ja Tarmo Maiste arhitektuuribüroost Male Arhitektid. Kolmas preemia - märgusõna "Pärand", arhitekt Liina Jaanus
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Martin Solders
2017-01-01
Full Text Available The maternal part of the placenta, the decidua, consists of maternal immune cells, decidual stromal cells, and extravillous fetal trophoblasts. In a successful pregnancy, these cell compartments interact to provide an intricate balance between fetal tolerance and antimicrobial defense. These processes are still poorly characterized in the two anatomically different decidual tissues, basalis and parietalis. We examined immune cells from decidua basalis and parietalis from term placentas (n=15 with flow cytometry. By using multivariate discriminant analysis, we found a clear separation between the two decidual compartments based on the 81 investigated parameters. Decidua parietalis lymphocytes displayed a more activated phenotype with a higher expression of coinhibitory markers than those isolated from basalis and contained higher frequencies of T regulatory cells. Decidua basalis contained higher proportions of monocytes, B cells, and mucosal-associated invariant T (MAIT cells. The basalis B cells were more immature, and parietalis MAIT cells showed a more activated phenotype. Conventional T cells, NK cells, and MAIT cells from both compartments potently responded with the production of interferon-γ and/or cytotoxic molecules in response to stimulation. To conclude, leukocytes in decidua basalis and parietalis displayed remarkable phenotypic disparities, indicating that the corresponding stromal microenvironments provide different immunoregulatory signals.
Mentorklubi süstib väikeettevõtjale tegutsemiskindlust / Teeli Remmelg
Remmelg, Teeli
2005-01-01
Tallinna Mentorklubi tegevusest, kus väikeettevõtjad õpivad üksteise vigadest ja õnnestumistest. Kommenteerivad EASi mentorprogrammi koordinaator Liina Võrkaed ja Pro Konsultatsioonid, Tallinna Mentorklubi mentor Mait Raava
Kaebus sunnib teatreid suitsetamise osas aru pidama
2009-01-01
Draamateatri külastaja kaebuse peale - etenduses "Pedro Páramo" suitsetas näitleja Mait Malmsten kogu esimese vaatuse - arutab Eesti Etendusasutuste Liit peagi laval suitsetamisega seotud küsimusi
Role of non-conventional T lymphocytes in respiratory infections: the case of the pneumococcus.
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Stoyan Ivanov
2014-10-01
Full Text Available Non-conventional T lymphocytes constitute a special arm of the immune system and act as sentinels against pathogens at mucosal surfaces. These non-conventional T cells (including mucosal-associated invariant T [MAIT] cells, gamma delta [γδ] T cells, and natural killer T [NKT] cells display several innate cell-like features and are rapidly activated by the recognition of conserved, stress-induced, self, and microbial ligands. Here, we review the role of non-conventional T cells during respiratory infections, with a particular focus on the encapsulated extracellular pathogen Streptococcus pneumoniae, the leading cause of bacterial pneumonia worldwide. We consider whether MAIT cells, γδ T cells, and NKT cells might offer opportunities for preventing and/or treating human pneumococcus infections.
Vene Kultuurikeskus = The Russian Culture Centre / Margit Mutso
Mutso, Margit, 1966-
2010-01-01
Tallinnas Mere puiestee 5 asuva hoone (arhitekt A. Kuznetsov, 1954) restaureerimisest. Arhitekt Niina Mäger, sisearhitekt Anne Tamverk. Ajaloolane Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud hoonele
Inimesed ja mesilased / Rein Tootmaa
Tootmaa, Rein
2005-01-01
Nukufilm "Gene+ratio" : stsenarist, kunstnik ja režissöör Mait Laas : konsultant Paavo Matsin : operaatorid Ragnar Neljandi, Raivo Möllits : helilooja Tiit Kikas : Nukufilm OÜ - Icon Film (Saksamaa) 2005
Tri gorsti za Tsentralnõi rõnok / Arvi Tapver
Tapver, Arvi
1999-01-01
Mõrvatud endise abilinnapea Mait Metsamaa keskturu erastajatest kaaskond kahlustas tunnistaja sõnul topeltmängu, kui Metsamaa vanale sõbrale ja allilmas kardetavale Meelis Laole erastamisest loobumise eest hüvitist pakkus
Vana kaader järel-eesti ajal võimalusi proovimas / Maie Kalda
Kalda, Maie, 1929-2013
2001-01-01
Artikkel põhineb konverentsil "Kohandumise märgid" (20. apr. 2001) peetud ettekandel. Kirjanike elu- ja loominguloost a-tel 1944-1948, lähemalt Mait Metsanurgast, Hugo Raudsepast, Friedebert Tuglasest ja Oskar Lutsust
Tallinna Loomeinkubaator = Creative Incubator in Tallinn / Margit Mutso
Mutso, Margit, 1966-
2010-01-01
Tallinnas Veerenni 24C asuva Tallinna Loomeinkubaatori sisekujundusest. Sisearhitektid Raul Tiitus, Tarmo Piirmets (Pink OÜ), graafiline kujundus: Kaarel Vahtramäe (Velvet Studio). Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud sisekujundusele
Juutide uurimine tõi tunnustuse : eesti teadlaste artikkel jõudis maailma tippajakirja / Marju Himma
Himma, Marju
2010-01-01
Juutide erinevate kogukondade genotüübilistele erinevuste uurimisrühma juhtideks olid Tartu Ülikooli ja Eesti Biokeskuse teadlased Doron M. Behar, Bayazit Yunusbayev, Mait Metspalu ja Richard Villems. Artikkel ilmus teadusajakirjas Nature
Esilinastus väge täis "Mina olin siin" / Kutt Kommel
Kommel, Kutt
2008-01-01
Rene Vilbre noortefilm "Mina olin siin", mille aluseks on Sass Henno romaan "Mina olin siin. Esimene arest" : operaator Mait Mäekivi : osades Rasmus Kaljujärv, Hele Kõre jt : Amrion Productions - Helsinki-filmi OY 2008
2008-01-01
Arvutiga animeeritud USA koguperefilmist "Madagaskar 2" (lavastanud Tim McGrath ja Eric Darnell, eesti keeles loevad teksti Karol Kuntsel, Andero Ermel, Evelin Pang, Argo Aadli, Mait Malmsten, Raivo E. Tamm, Andrus Vaarik, Anne Reemann jt)
Endine turujuht end süüdi ei tunnistanud / Hannes Krause
Krause, Hannes
2005-01-01
Vadim Polishtshuk, keda süüdistatakse koos kahe kaaslasega Mait Metsamaa mõrvaprotsessi peamise tunnistaja ähvardamise ja mõjutamise katses, ei tunnistanud end 19. septembril Tallinna linnakohtus alanud protsessil süüdi
Akna varastamine : eesti Y-kirjandus / Berk Vaher
Vaher, Berk, 1975-
2014-01-01
Valdur Mikita, Erkki Luuk'i, Kiwa, Kaspari ja kirjanike rühmituse “14 NÜ” (Mait Laas, Paavo Matsin, Marko Mägi, Erkki Kadarik, Marianne Ravi, Maarja Vaino, Trip Jarvis, Johannes Üksi) loomingust
Eesti animafilmid võitsid Raumas
pPIK mare 2010
1999-01-01
VI Sinise Mere filmifestivalil Raumas jagasid A-sarjas esikohta Mait Laasi "Päevavalgus" ja Peep Pedmansoni "Just Märried", teiseks jäi Märt Sildvee "Guardian Angel" ja kolmandaks Riho Undi - Hardi Volmeri "Primavera"
Nukufilm lasi käiku pooletunnise 3D-seiklusfilmi / Tiit Tuumalu
Tuumalu, Tiit, 1971-
2009-01-01
Stuudios Nukufilm algasid pooletunnise 3D-nukufilmi "Lisa Limone ja Maroc Orange'i tormakas armulugu" võtted. Filmi režissöör on Mait Laas, stsenaristid Kati Kovacs ja Peep Pedmanson, produtsent Arvo Nuut
Inimkatse blondi eesti naise peibutustest Egiptuses / Liivi Shein
Šein, Liivi
2006-01-01
ETVs esilinastus 23. nov. "Eesti lugude" sarjas valminud "1001 öö muinasjutt ehk eesti naiste imelised seiklused Egiptuses" : režissöör Elo Selirand : toimetaja Anne-Mari Neider : operaator Mait Mäekivi : Osakond OÜ 2006
"Mina olin siin", võib vastu hambaid saada / Andres Keil
Keil, Andres, 1974-
2007-01-01
Noortefilmi "Mina olin siin" võtetel. Filmi aluseks on Sass Henno romaan "Mina olin siin. Esimene arest", stsenaariumi kirjutas Ilmar Raag, lavastab Rene Vilbre, operaator on Mait Mäekivi, peaosas Rasmus Kaljujärv, produtsendiks Riina Sildos
Meie mees Berliinis / Lauri Kärk
Kärk, Lauri, 1954-
2005-01-01
Berliini 55. filmifestivalist : Eesti filmist festivalil (Euroopa noorte režissööride lühifilmidest koosnevat projekti "Kaotatud ja leitud" raamib Mait Laasi nukufilm "Gener+atio"), inglaseDavid MacKenzie mängufilmist "Pelgupaik" ("Asylum")
Kirjandus ja vabamüürlus / Paavo Matsin
Matsin, Paavo, 1970-
2009-01-01
Loetletakse vabamüürlastest kirjanikke (pikemalt Jules Verne'ist, Gustav Meyrinkist, Rudyard Kiplingist ja Mait Metsanurgast) ning vabamüürlikke tegelasi või motiive kasutanud kirjanikke (Lev Tolstoi, Fjodor Dostojevski, Mihhail Bulgakov, Edgar Allan Poe)
Kuidas tuua Eestisse Tiger Woods / Raul Ranne
Ranne, Raul
2008-01-01
Reaalselt arvestades on tõenäosus, et Eestit väisab golfistaar Tiger Woods, muidugi olematu. Teoreetiliselt on see siiski võimalik. Vestlusest Jõelähtme golfiväljakut opereeriv Estonian Golf Country Clubi presidendi Mait Schmidtiga
Ilmafilosoofia ilma filosoofiata / Jüri Rato
Rato, Jüri
2000-01-01
Arvustus: Hoff, Benjamin. Puhh ja Tao / tlk. Mait Talts. Tln. : Olympia, 1998 ; Hoff, Benjamin. Notsu ja Te / tlk. Paavo Kivine. Tln.: Olympia, 1999 ; Allen, Roger E. ; Allen, Stephen D. Puhh lahendab probleeme / tlk. Paavo Kivine. Tallinn : Olympia, 2000
Armastuse anatoomia / Peeter Laurits
Laurits, Peeter, 1962-
2007-01-01
Mängufilmist "Nuga" Peeter Sauteri ja Vaino Vahingu jutustuste motiividel : režissöör Marko Raat : peaosas Mait Malmsten : Allfilm, 2007. Samuti ka M. Raadi hiljuti valminud dokumentaalfilmist "F.F.F.F. läheb laiali"
Algasid Henno "Mina olin siin" järgi tehtava filmi võtted
2007-01-01
Eile algasid noortefilmi "Mina olin siin" võtted. Filmi aluseks on Sass Henno romaan "Mina olin siin. Esimene arest", stsenaariumi kirjutas Ilmar Raag, lavastab Rene Vilbre, operaator on Mait Mäekivi, peaosas Rasmus Kaljujärv, produtsendiks Riina Sildos
Improviseeritud lugu ja zhanriga mäng / Donald Tomberg
Tomberg, Donald
2003-01-01
Eesti komöödiafilm "Vanad ja kobedad saavad jalad alla" : režissöör Rando Pettai : operaator Mait Mäekivi : näitlejad Henrik Normann, Madis Milling, Robert Gutman jt. : muusika - ansambel Genialistid : Ruut Pictures 2003
2008-01-01
Küsimusele vastab Räpina aianduskooli direktor Heino Luiga, Järvamaa kutsehariduskeskuse põllumajanduse erialade juhtiv õpetaja Vello Vilu, Eesti talupidajate keskliidu peadirektor Kaul Nurm, Olustvere teenindus- ja maamajanduskooli direktor Arnold Pastak ning maaülikooli rektor Mait Klaassen
Keskmiselt kobe vaatamine / Küllike Rooväli
Rooväli, Küllike, 1969-
2004-01-01
Eesti komöödiafilm "Vanad ja kobedad saavad jalad alla" : režissöör Rando Pettai : operaator Mait Mäekivi : näitlejad Henrik Normann, Madis Milling, Robert Gutman jt. : muusika - ansambel Genialistid : Ruut Pictures 2003
Directory of Open Access Journals (Sweden)
Ayako Ishimori
2017-04-01
Conclusions: For the first time, our data showed that activated NK cells, ILC1s, ILC2s, ILC3s, and MAIT cells were positively correlated with each other and may be associated with airflow limitation in patients with asthma.
Poolsajandi õnnesoovid Jaak Aaviksoole / Ain Heinaru, Jaak Kangilaski, Tõnu Lehtsaar...[jt.
2004-01-01
Mõtteid Tartu Ülikooli rektorist tema 50. sünnipäeva puhul : Ain Heinaru, Jaak Kangilaski, Tõnu Lehtsaar, Indrek Reimand, Toomas Kiho, Leelo Kriisa, Peeter Olesk, Risto Tammelo, Birute Klaas, Peeter Saari, Andrus Ansip, Mait Klaassen, Marika Kullamaa, Kaupo Bend
Lihtsamatele töödele napib ladudes ja terminalides tööjõudu / Rivo Sarapik
Sarapik, Rivo, 1981-
2005-01-01
Ilmunud ka: Delovõje Vedomosti 2. nov. lk. 17. Teravnemas on terminali- ja laotööliste puudus, sest lihttöödele on keeruline töötajaid leida. Kommenteerivad: Andres Leht, Annika Lootus, Mait Miller ja Margus Tammaru
Absurd on igihaljas / Vaapo Vaher
Vaher, Vaapo, 1945-
2006-01-01
Tutvustus: Camus, Albert. Õnnelik surm / tõlkinud Tanel Lepsoo. Tallinn : Varrak, 2005 ; Metsanurk, Mait. Kreeps / koost. Maire Liivamets. Tallinn : Eesti Raamat, 2005. (Eesti novellivara). Järg: 23. veebr., lk. 27, sisaldab Aivar Kulli kriitikakogu "Kulli pilk" (Ilmamaa, 2005) tutvustust
Sodom i Gomorra v glamurnoi miniatjure / Boris Tuch
Tuch, Boris, 1946-
2006-01-01
Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions
Kas kõik poisid tahavad endale koju Barbit? / Andris Feldmanis
Feldmanis, Andris, 1982-
2006-01-01
Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions
Geishade kataloog "Kuldrannakesel" / Kati Murutar
Murutar, Kati, 1967-
2006-01-01
Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions
Vääritu film / Linnar Priimägi
Priimägi, Linnar, 1954-
2006-01-01
Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions
Lihtsameelsed päästavad maailma / Urve Eslas
Eslas, Urve, 1972-
2006-01-01
Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions
Homme esilinastuv uus Eesti film "Kuldrannake" flirdib terrorismiteemaga / Andris Feldmanis
Feldmanis, Andris, 1982-
2006-01-01
Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions
Ruus, Jaan, 1938-2017
2006-01-01
Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions
Vilma lõpetab leivateo / Marko Suurmägi
Suurmägi, Marko, 1975-
2008-01-01
Vilma emafirma Kalev Chocolate Factory juhatuse liikme Mait Nilsoni sõnul jagab Kalev jahutoodete tegemise Jõhvi ja Viljandi ettevõtte vahel nii, et leiba ja saia hakatakse küpsetama Jõhvis ning Viljandisse koondub tortide, kookide ja jahusegude valmistamine. Lisa: Ajalugu
Eesti teadlaste artikkel juutide põlvnemisest jõudis tippajakirja / Marju Himma
Himma, Marju
2010-01-01
Eesti ja Iisraeli teadlaste rühm uuris juutide geneetilist sarnasust üle maailma. Artikkel avaldati rahvusvahelises teadusajakirjas Nature. Uurimisrühma juhtideks olid Tartu Ülikooli ja Eesti Biokeskuse teadlased Doron M. Behar, Bayazit Yunusbayevi, Mait Metspalu ja Richard Villems
Delta Plaza kohvik = The Delta Plaza Café / Margit Mutso
Mutso, Margit, 1966-
2010-01-01
Tallinnas Pärnu mnt. 141 asuva kohviku Delta Plaza sisekujundusest. Sisearhitektid Tiiu Truus ja Marja Viltrop (Stuudio Truus OÜ). Hoone arhitektid Jüri Okas ja Marika Lõoke (AB J. Okas & M. Lõoke). Žürii liikme Mait Summataveti arvamus kohvikust
Ellen Aitsam - õpetaja kõige paremas mõttes / Tiia Truu
Truu, Tiia
2007-01-01
Persoonilugu 33 aastat Vigalas keemia-, biloogia- ja geograafiaõpetajana töötanud Ellen Aitsamist. Mare Mursak-Ülemaante; Jaan Moor; Evi Tikerpalu-Andrejev; Elme Tiits-Moor: Mis meenub õpetaja Ellen Aitsamist?
101 riigikogulast said valijalt ehmatava liputervituse / Tuuli Koch
Koch, Tuuli
2006-01-01
Ilmunud ka: Postimees : na russkom jazõke 4. sept. lk. 4. Valija Tiina Talts saatis presidendivalimiste esimese päeva hommikul parlamendiliikmetele kirja, mille juurde oli ümber disainitud Eesti lipp. Vastused saatsid neli saadikut, nende hulgas Mait Klaassen, Jaak Allik, Janno Reiljan
Nõmme Lunastaja kirik = The Saviour's Lutheran Church in Nõmme / Margit Mutso
Mutso, Margit, 1966-
2010-01-01
Tallinnas Õie 10 asuva kirikuhoone (arhitekt Robert Natus, 1932) restaureerimisest. Arhitekt Fredi-Armand Tomps, sisearhitekt Anne Koppel, ehitusjärelevalve: Rein Joller, ajaloolane Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang EK arhitektuuri sihtkapitali 2009. a. restaureerimispreemia pälvinud hoonele
Toompea komandandimaja = The Commandant's House in Toompea / Margit Mutso
Mutso, Margit, 1966-
2010-01-01
Tallinnas Toompea 1 asuva hoone restaureerimisest. Arhitekt Raul Vaiksoo, kaasautor Kristo Vaiksoo (Raul Vaiksoo Arhitektuuribüroo), sisearhitektid Priit Põldme, Rita Rahu (SAB Joonprojekt), Raul Vaiksoo, ajaloolased Raul Vaiksoo, Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud hoonele
Võtme ja riiviga tantsufilm / Kristiina Garancis
Garancis, Kristiina, 1969-
2005-01-01
Rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov : Eesti - Island 2005
Rohkem kui lihtsalt tantsufilm / Tiit Tuumalu
Tuumalu, Tiit, 1971-
2005-01-01
Rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov : Eesti - Island 2005
Paugub püstol, lendavad kilud / Olev Remsu
Remsu, Olev, 1947-
2006-01-01
Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions. Pikemalt stsenaariumist
Superorgaaniline animatsioon / Jan Kaus
Kaus, Jan, 1971-
2006-01-01
Eesti uuemast animafilmist. Põhjalikumalt on käsitletud 2005.a. eesti animatsioonikunsti tippteosena Mait Laasi filmi "Generatio". Lisatud lühiandmed M. Laasi kohta, samuti kuue riigi koostööfilmi "Kaotatud ja leitud" kohta, mille lühifilmid seob tervikuks "Generatio"
Meie näitekirjandus aastal 1931 / Ants Oras
Oras, Ants, 1900-1982
2009-01-01
Ülevaade 1931. aasta eesti näitekirjandusest. Pikemalt käsitletakse: Mait Metsanurk "Mässuvaim, ehk, Agulirahvas läheb ajalukku", Hugo Raudsepp "Põrunud aru õnnistus", Agnes Taar "Emake maamuld", Aleksander Antson "Töölise tütar", Artur Adson "Neli kuningat"
Näitleja Anti Reinthal : "Kui sa just surnud ei ole, siis mängid lõpuni!" / Katrin Rohtla
Rohtla, Katrin, 1966-
2007-01-01
Viinistu kunstimuuseumis etenduva Eesti Draamateatri suvelavastuse "Sürrealistid" 30. juuni etenduses vigastas näitleja raskelt oma reielihast kuid mängis lõpuni. Lisaks Mait Malmsteni kommentaar "Malmsten : "Esimene vaatus mängiti fantaasia abil" ja vaataja arvamus : "Publiku pettis ära"
Arhitektuurivõistlused 2008 / Mait Väljas
Väljas, Mait
2008-01-01
Võistluste tulemused: Pekingi saatkonnahoone: I preemia - A. Põime, L. Põime, L. Vaimel; Riia saatkonnahoone: I - L.-K. Stöör, Ü.-T. Stöör, H. Urb; Eesti Kunstiakadeemia uus õppehoone: I - SEA + Effekt (Taani); Eesti Maaülikooli Kreutzwaldi 5 õppehoone juurdeehitis: I - P. Loo, J. Skolimowski, L. Vene, K. Kruuse (KAMP Arhitektid); TÜ Viljandi Kultuuriakadeemia loomeinkubaatori ja lavakunstide õppehoone: I - S. Vallner, H. Urb, I. Peil, H. Lass, S.-M. Mändmaa (Kavakava); Tamula järve ranna-ala mahuline planeering: I - K. Enno, L. Luhse, M. Zeleznova, R. Ailt (K. Enno Arhitektuuribüroo); Tartu pärmivabriku kvartali arhitektuurivõistlus: võidutöö - Atelier Thomas Pucher / Bramberger Architects (Austria); Paldiski mnt. 50 kinnistu ja lähiala: I-II - T. Laigu, K. Ojaliiv, M. Rass, A. Uukado (QP Arhitektid); maastikuarhitektuuri võistlus "Eesti Maaülikooli Tähtvere linnaku välialad": I - H. Runnel, T. Ong; Tartu rahu tähisala kujundus: I - M. Kinks, K. Süda; Veneetsia XI rahvusvahelise arhitektuuribiennaali ideekavandi võistlus: I - M. Kask, R. Lõoke, N. Külm; aasta betoonehitis 2007 - Puurmani kaarsild, konstruktorid S. Idnurm, J. Idnurm; Eesti parim puitehitis 2008: eramu Loobul - R. Vaiksoo; võistluse "Eramu 2006-2007" peapreemia: villa Paldiskis - S. Vallner, I. Peil
Birma - otsekui retk minevikku / Mait Talts
Talts, Mait, 1964-
2011-01-01
Reisist Birmasse, tänapäevase nimega Myanmari, mida Eestiga seovad sinna maetud "Eestimaa budistlikud peapiiskopid" Karl A.M. Tõnisson-Tennisons (Vend Vahindra, 1883-1962) ja Friedrich Voldemar Lustig (Ashin Ananda, 1912-1989)
Baltika büroo = The Baltika Offices / Margit Mutso
Mutso, Margit, 1966-
2010-01-01
Tallinnas Veerenni 24 asuvast Baltika büroost. Arhitektuur, bürooruumide kujundus: AB Studio 3, Kolm Pluss Üks Arhitektid. Žürii liige Mait Summatavet žürii hinnangust EK arhitektuuri sihtkapitali 2009. a. sisearhitektuuri preemia pälvinud bürooruumidele
Jüri Sillart alustab uue mängufilmi võtteid / Mart Rummo
Rummo, Mart
2005-01-01
J. Sillart alustas Maardu mõisas uues mängufilmi "Kuldrannake" võtteid. Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik sen oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsent Kristian Taska, tootjafirmaks Taska Productions
Kuldrannakese virvatuled / Tarmo Teder
Teder, Tarmo, 1958-
2006-01-01
Jüri Sillarti mängufilmi "Kuldrannake" eilse esilinastuse puhul. Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik sen oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions
Eesti osaleb suurejoonelises filmiprojektis
pPIK mare 2010
2004-01-01
Filmiprojekt tööpealkirjaga "Generation", mis on plaanitud täispikaks mängufilmilaadseks filmiks. Tegemisse on kaasatud kuus noort režissööri Ida-Euroopast. Eestit esindab animafilmide režissöör Mait Laas, kes teeb valmivale filmile raamjutustuse
Loomad räägivad sel korral eesti keeles / Jaanus Noormets
Noormets, Jaanus
2008-01-01
Arvutiga animeeritud USA koguperefilmist "Madagaskar 2" (Madagascar: Escape 2 Africa), mis jõuab Eesti kinodesse erinevalt filmisarja esimesest osast eesti keelde dubleerituna (loomtegelastele on oma hääle laenanud Karol Kuntsel, Andero Ermel, Evelin Pang, Mait Malmsten, Raivo E. Tamm, Andrus Vaarik jt)
Vanglamüüride vahel võeti üles tantsufilmi / Villu Päärt
Päärt, Villu, 1972-
2005-01-01
ETV-l valmib koos EFS-i ja Estinfilmiga kultuurikanali ARTE tellimusel tantsufilm "Teine" : režissöör Rene Vilbre : stsenarist Teet Kask : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov. Filmi võtetest Tartu vanglas
Jõgeva bussijaam sai liimpuidu kasutamise eripreemia
2009-01-01
Konkursil Eesti Parim Puitehitis 2009 sai liimpuidu kasutamise eripreemia Jõgeva bussijaam, arhitektid Andres Lunge ja Mait Lauri firmast Lunge & Co OÜst. Peapreemia pälvis suvila Jõelähtmel, arhitekt Sten Ader büroost SKAD Arhitektid. Loetletud ka teisi auhinnalistele kohtadele tulnud töid
Tartu kalendritootja investeeris uude tehasesse 100 miljonit / Kadrin Karner
Karner, Kadrin
2008-01-01
Ilmunud ka: Delovõje Vedomosti 24. sept. lk. 5. Tartus avatud Ajasto Diary Groupi kalendritehasesse investeeriti üle 100 miljoni krooni, mille tasuvuspiiriks loeb ettevõte umbes kümme aastat. Vt. samas: Mis on mis: Ajasto Diary Group; Kommenteerivad: Mait Puusepp, Andras Metsa, Kadrin Karner
Vanglarahvas tantsib Euroopasse / Andres Laasik
Laasik, Andres, 1960-2016
2005-01-01
Rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov. Filmi võtted toimusid Tartu vanglas
Tantsuime: märjaks nutetud Märt Agu saab 8000 uut sõpra / Märt Agu ; intervjueerinud Rein Sikk
Agu, Märt, 1980-
2011-01-01
11. Noorte tantsupeo "Maa ja ilm" üldjuht ja Tallinna Tantsuakadeemia kunstiline juht Märt Agu Tallinna lauluväljakul toimuvast tantsupeost, ülevaatustest, eesti meeste rahvatantsust, oma isast Mait Agust, tema tantsust "Põhjamaa", tantsuõpetaja elukutsest, eesti tantsust, Tallinna Tantsuakadeemiast. Andmeid Märt Agu loomingu kohta
Võigas ja seletamatu tsirkus : kaasaja ja alateadvuse pained "Agent Sinikaelas" / Sven Vabar
Vabar, Sven
2002-01-01
Mängufilm "Agent Sinikael" : stsenaristid Marko Raat ja Andres Maimik : režissöör Marko Raat : operaator Arko Okk : helilooja Janek Murd : kunstnikud Margus Tammik ja Jaana Jüris : nimiosas Mait Malmsten : produtsendid Peeter Urbla ja Veiko Õunapuu : Exitfilm ja Suhkur Film, 2002
Vikergallup : eesti kirjandus 2012 / Vahur Afanasjev, Joanna Ellmann, Peeter Helme ... [jt.
2013-01-01
Erinevate kriitikute arvamus 2012. aastal Eestis ilmunud nüüdiskirjandusest. Aasta parimaks uudisteoseks nimetati Peeter Sauteri "Märkmeid vaeste kirjanike majast", parimaks debüüdiks Mait Vaigu luulekogu "Kõigil on alati õigus", parimaks tõlkeraamatuks Georges Pereci romaan "Elu, kasutusjuhend" ja Pentti Saarikoski koondkogu "Luuletused"
Nick Park pani Wallace'ile ja Gromitile libaküüliku needuse / Mart Rummo
Rummo, Mart
2005-01-01
Uus animafilm "Wallace ja Gromit : Libaküüliku needus" ("Wallace & Gromit : The Curse of the Were-Rabbit") : režissöör Nick Park : Suurbritannia 2005. Selle loojast ja tema loometeest. Lisatud : Nick Park (filmograafia, auhindu), "Teised Nick Parkist" (Lauri Kaare, Mait Laas, Riho Unt)
Kuus uut Eesti filmi korraga ekraanil / Tarmo Teder
Teder, Tarmo
1998-01-01
21. mail esilinastuvad kinos Sõprus 'Just märried', rezh. Peep Pedmanson; 'Päevavalgus', rezh. Mait Laas; 'Primavera', rezh. Riho Unt ja Hardi Volmer; 'Vares ja hiired', rezh. Priit Tender ja Mikk Rand; 'Bermuda', rezh. Ülo Pikkov; 'Tom ja Fluffy', rezh. Janno Põldma ja Heiki Ernits
Sõpruses esilinastub Eesti-Islandi tantsufilm
2005-01-01
10. novembril esilinastub rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov. Filmi võtted toimusid Tartu vanglas
Rand, Jaak
2006-01-01
Jüri Sillarti mängufilm "Kuldrannake". Kunagise retrobändi kokkutulekut kujutava filmi stsenarist on Hans Luik oma näidendi "Tõe hetk" põhjal, operaator on Mait Mäekivi, produtsendid Kristian Taska ja Hans H. Luik, tootjafirmaks Taska Productions. Lisatud Jüri Sillarti filmograafia lk. 83
Nirvaana, susla ja internet / Tarmo Teder
Teder, Tarmo, 1958-
2000-01-01
Kolm stuudio Nukufilm uut nukufilmi : "Saamueli Internet" : Stsenarist Andrus Kivirähk : režissöör ja kunstnik Riho Unt; "Teekond Nirvaanasse" : Stsenarist, režissöör ja kunstnik Mait Laas; "Eilne vedur" : režissöörid Mikk Rand ja Kalju Kivi
Ilma tahtmata ja teadmata paradiisi ehk Arhetüüp eesti moodi / Rein Tootma
Tootma, Rein
2006-01-01
Lühimängufilm "Vanameeste paradiis" : stsenaristid Ove Musting (ka idee autor), Urmas Lennuk : režissöör Ove Musting : operaator Mait Mäekivi : helilooja Arian Levin : kunstnik Eva-Marina Gramanovski : näitlejad Tõnu Aav, Aleksander Eelmaa, Tõnu Oja, Ants Ander, Henry Kõrvits : Downtown Pictures 2005
Ära kosi Pikka: Pikk läheb pingile magama / Meelis Oidsalu
Oidsalu, Meelis, 1978-
2010-01-01
Kevadel lavakunstikooli lõpetavate tudengite lavastusest "Pikk pink" , mis koosneb kuuest lühiloost - Mait Jooritsa "Kantani padi", Kristjan Üksküla "Jääger" ja "Albioni tütar", Roland Laosi "Genees ja katastroof", Hendrik Toompere jun. "Karupoeg Puhh" ja Kerttu Moppeli " Leib!". Esietendus 23. nov. Hobuveskis
Lavaka lõpetajate pink on pikk / Tiiu Laks
Laks, Tiiu, 1984-
2009-01-01
Kevadel lavakunstikooli lõpetavate tudengite lavastusest "Pikk pink" , mis koosneb kuuest lühiloost - Mait Jooritsa "Kantani padi", Kristjan Üksküla "Jääger" ja "Albioni tütar", Roland Laosi "Genees ja katastroof", Hendrik Toompere jun. jun. "Karupoeg Puhh" ja Kerttu Moppeli " Leib!". Etendused toimuvad Hobuveskis
Eesti animafilmid Ottawas / M. L.
M. L.
2006-01-01
Ottawa rahvusvahelisel animafilmifestivalil 20.-24. sept. võistlesid Eesti poolt Mati Küti "Une instituut" ja "Vulcain.Cricet", Priit Tenderi "Sõnum naabritele", Ülo Pikkovi "Elu maitse" ja Mait Laasi "Generatsioon". Eesti auhindu ei saanud. Peaauhind täispika animatsiooni eest läks inglasele Phil Mulloy'le filmi "Christied" eest
"Riigikogu hoone 90" = "Estonian parliament building 90" / Janno Roos, Andres Labi
Roos, Janno, 1976-
2013-01-01
Eesti Sisearhitektide Liidu 2012. aasta näituse kujunduse preemia pälvinud näitusest (Lossiplats 1A). Kujunduse autorid Janno Roos ja Andres Labi (Ruumilabor). Kuraator Mait Väljas. Graafiline disain: Identity. Sisearhitekti ja ESLi aastapreemiate žürii liikme Mari Kurismaa ning arhitektuuriajaloolase Leele Välja arvamused
2009-01-01
Tutvustatakse Tallinna Tehnikakõrgkooli Arhitektuuri Instituudi arhitektuuri eriala üliõpilaste töid teemal "Väikeelamine suureks - normaalpere konteinersüsteemis". Idee: rahuldada ühesuuruste "konteinerite" baasil ehitatud torn- või ridamajadega väikekorterite nõudlust. Juhendaja: sisearhitekt Mait Summatavet (lk. 60 andmeid M. Summataveti elu ja loomingu kohta)
2005-01-01
Täna on ETV-s rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre : stsenaristid Rene Vilbre, Teet Kask, Helena Jonsdottir : produtsent Heidi Pruuli : koreograaf ja peaoaline Helena Jonsdottir : osatäitjad Mait Malmsten, Ruslan Stepanov. Filmi võtted toimusid Tartu vanglas
Paariselamu Luccas = Duplex House in Lucca / Indrek Allmann
Allmann, Indrek, 1972-
2001-01-01
Projekteerija: Arhitektuuribüroo Kolde Grupp. Arhitekt Indrek Allmann, konstruktorid Andres Läänesaar, Aldur Parts, Valdo Jaanisoo, Mait Mets. Hoone asub panga ülemise tasandi kõrgusel õhus, pangapealsega on ühendatud terrassi abil, ligipääs alumisel tasandil. Projekt 1999, valmis 2001. 5 ill.: põhiplaan, vaated
The Utility of the Metacognitive Awareness Inventory for Teachers among In-Service Teachers
Kallio, Heli; Virta, Kalle; Kallio, Manne; Virta, Arja; Hjardemaal, Finn Rudolf; Sandven, Jostein
2017-01-01
The purpose of the present study is to explore the utility of the compressed version of the Metacognitive Awareness Inventory for Teachers (MAIT-18) among in-service teachers. Knowledge of teachers' awareness of metacognition is required to support students' self-regulation, with the aim of establishing modern learning methods and life-long…
432 püksipaari Riia kongresside palee fassaadil / Lauri Kärk
Kärk, Lauri, 1954-
2000-01-01
Filmifestivalil "Arsenals" sai parima režissööri kujukese Mait Laas nukufilmi "Teekond Nirvaanasse" eest, teise koha preemia Valentin Kuigi mängufilm "Lurjus" ja Riho Undi nukufilm "Saamuel internetis". Peaauhinna andis loos shoti naisrežissööri Lynne Ramsay mängufilmile "Rotipüüdja" ("Ratcatcher")
Sinikael jätab jälgi / Tristan Priimägi
Priimägi, Tristan, 1976-
2002-01-01
Mängufilm "Agent Sinikael" : stsenaristid Marko Raat ja Andres Maimik : režissöör Marko Raat : operaator Arko Okk : helilooja Janek Murd : kunstnikud Margus Tammik ja Jaana Jüris : nimiosas Mait Malmsten : produtsendid Peeter Urbla ja Veiko Õunapuu : Exitfilm ja Suhkur Film, 2002. Lisatud Marko Raati filmograafia lk. 103
Lastemuuseum Miia-Milla-Manda = The Miia-Milla-Manda Children's Museum / Margit Mutso
Mutso, Margit, 1966-
2010-01-01
Tallinnas Koidula 21A asuva hoone restaureerimisest, lastemuuseumi sisekujundusest. Kadrioru Lastepargi paviljoni (arhitekt Villem Seidra, 1937) renoveerimisprojekti tegi arhitekt Katrin Etverk, sisearhitektid ja ekspositsiooni kujundus: Maile Grünberg, Eliina Grünberg (Grünberg oü). Ajaloolane Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud hoonele
Tudengite nappus seab kõrgkoolid raskustesse / Madis Filippov
Filippov, Madis
2008-01-01
Gümnasistide arvu vähenemine nõuab kõrgkoolide töö ümberhindamist. Arvamust avaldavad Tallinna Ülikooli rektor Rein Raud, Tartu Ülikooli rektor Alar Karis, Eesti Maaülikooli rektor Mait Klaassen, Euroülikooli rektor Jüri Martin, Estonian Business Schooli rektor Peeter Kross ja haridusminister Tõnis Lukas
Karmid mängud / Kristel Raesaar
Raesaar, Kristel
2000-01-01
Tüli puiduärimehega maksis Hansapangale üle 100 miljoni. Lisa: ühed faktid, mitu tõlgendust - Hansapanga kreedidirektor Aivar Rehe, ECT tegevjuhi Arvi Schilfi ja laenu varjamises süüdistatud Hansapanga endise väliskaubanduse finantseerimise osak. juhataja Mait Kolditsa nägemus ECT laenuraha kadumisega seotud sündmustest
Paulus, Karin, 1975-
1998-01-01
Eesti valgustikujundajatest ja valgustitest. Kas eesti disaineritel on õnnestunud leida oma nišš lambiletil. Tootjatest : OÜ "Raunto", AS "Titanus" (disaineriks Eestis elav rootslane Renni Par)-, Norrast pärineva kontserni "Glamox" tehasest Keilas, "Estoplastist" (disainerid Martin Pärn, Raido Laasing), AS "Steel Line". Valgustikujundajatest Tarmo Luisust, Aleksander Jakovlevist, Raivo Pristolist, Mait Summatavetist, Tõnis Vellamast
Põlvas näeb Ove Mustingu filmi / Tiia Allas
Allas, Tiia
2006-01-01
8. jaan. linastub Põlva kultuurikeskuses lühimängufilm "Vanameeste paradiis" : stsenaristid Ove Musting (ka idee autor), Urmas Lennuk : režissöör Ove Musting : operaator Mait Mäekivi : helilooja Arian Levin : kunstnik Eva-Marina Gramanovski : näitlejad Tõnu Aav, Aleksander Eelmaa, Tõnu Oja, Ants Ander, Henry Kõrvits : Downtown Pictures 2005
Multifilm kui tõsine asi / Marko Mägi
Mägi, Marko
1998-01-01
Esilinastus 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer
Eesti animafilme igale maitsele / Sulev Teinemaa
Teinemaa, Sulev, 1947-
1998-01-01
Esilinastus 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer
Aimdusi tsivilisatsioonist / Tarmo Teder
Teder, Tarmo, 1958-
1998-01-01
Esilinastus 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer
Animaalselt ja humaanselt / Karlo Funk
Funk, Karlo, 1971-
1998-01-01
Esilinastus 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer
Herbert Johansoni eeskujulikud koolimajad / Mait Väljas
Väljas, Mait
2010-01-01
Eesti arhitektuurimuuseumis eksponeeritava Herbert Johansoni (1884–1964) ja Eugen Habermanni (1884–1944) juubelinäituse taustal on kohane rääkida koolimajadest. Johansoni kontol on suur osa Tallinna sõdadevahelistest koolimajadest, kaks lasteaeda ja üks kutsekool
MAIT cells: new guardians of the liver
Kurioka, Ayako; Walker, Lucy J; Klenerman, Paul; Willberg, Christian B
2016-01-01
The liver is an important immunological organ that remains sterile and tolerogenic in homeostasis, despite continual exposure to non-self food and microbial-derived products from the gut. However, where intestinal mucosal defenses are breached or in the presence of a systemic infection, the liver acts as a second 'firewall', because of its enrichment with innate effector cells able to rapidly respond to infections or tissue dysregulation. One of the largest populations of T cells within the h...
Journal of Genetics | Indian Academy of Sciences
Indian Academy of Sciences (India)
TIMP2 gene polymorphisms are associated with hypertension in patients with myocardial infarction. José Manuel Rodríguez-Pérez Nancy Martínez-Rodríguez Gilberto Vargas-Alarcón Maite Vallejo Irma Eloisa Monroy-Muñoz Carlos Posadas-Romero Eric Kimura-Hayama Teresa Juárez-Cedillo José Manuel Fragoso ...
Nukufilmi erootika / Jaan Ruus
Ruus, Jaan, 1938-2017
2005-01-01
Kaks eesti nukufilmi - "Laud" : autorid Jelena Girlin ning Mari-Liis Bassovskaja : operaator ja kaasrežissöör Urmas Jõemees : helilooja Malle Maltis : Nukufilm OÜ 2004 ja "Generatio" : stsenarist, kunstnik ja režissöör Mait Laas : konsultant Paavo Matsin : operaatorid Ragnar Neljandi, Raivo Möllits : helilooja Tiit Kikas : Nukufilm OÜ - Icon Film (Saksamaa) 2005
Animatsiooni vastu ei saa ükski / Mikk Rand
Rand, Mikk, 1970-
1998-01-01
21.5. esilinastuvad kinos "Sõprus" 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer
Esilinastuvad eesti animafilmid
1998-01-01
21.5. esilinastuvad kinos "Sõprus" 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer
Kuus uut Eesti filmi korraga ekraanil / Tarmo Teder
Teder, Tarmo, 1958-
1998-01-01
21.5. esilinastuvad kinos "Sõprus" 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer
Short outlines of books by Estonian authors : [annotations] / Rutt Hinrikus, Janika Kronberg
Hinrikus, Rutt, 1946-
1999-01-01
Ehin, Andres. Seljatas sada meest; Ilmet, Peep. Tuuldunud luule; Kaplinski, Jaan. Öölinnud. Öömõtted; Kender, Kaur. Iseseisvuspäev; Kesküla, Kalev. Vabariigi laulud; Luik, Viivi. Maa taevas; Nõu, Helga. Hundi silmas; Raun, Mait. Wake up; Remsu, Olev. Haapsalu tragöödia; Sauter, Peeter. Kogu moos; Undusk, Jaan. Maagiline müstiline keel; Vint, Toomas. Kunstnikuromaan
Kodumaine multifilm õilmitseb / Mart Rummo
Rummo, Mart
2001-01-01
Tähistamaks eesti animafilmi 70. aastapäeva näidatakse täna Kinomajas kuut uut multifilmi : 13-osaline lamenukkfilm "Tulelaeva kulid" (režissöör Mait Laas), Ülo Pikkovi kaks joonisfilmi "Superlove" ja "Peata ratsanik", Priit Tenderi joonisfilm "Mont Blanc", Kaspar Jancise joonisfilm "Romanss" ja Janno Põldma - Heiki Ernitsa laste joonisfilmiseriaali "Lepatriinude jõulud" 5-min. trailer
Vabaduse väljak = The first design stage of Freedom Square / Margit Mutso
Mutso, Margit, 1966-
2010-01-01
Tallinna Vabaduse väljakust, mis pälvis Eesti Kultuurkapitali 2009. aasta aastapreemia uue kvaliteedi eest Eesti linnaehituses ja avaliku ruumi loomisel. Arhitektid: Andres Alver, Veljo Kaasik, Tiit Trummal, kaasautorid Indrek Rünkla, Tarmo Laht, Sven Koppel, Ulla Saar, Toomas Tammis (Alver Arhitektid OÜ). Ajaloolane Rein Zobel. Žürii liikmete Kalle Komissarovi ja Mait Summataveti hinnang väljakule
Tjoplõi dozhd v zale suda / Boris Tuch
Tuch, Boris, 1946-
2006-01-01
Mängufilm "Meeletu" : stsenaristid Jaan Tätte, Elmo Nüganen : režissöör Elmo Nüganen : operaator Mait Mäekivi : produtsent Kristian Taska : helilooja Jaak Jürisson : peaosas Rain Simmul : Taska Film - Eesti Televisioon 2006. Võrreldakse näidendi lavastust ja filmi. Arvustuses on Jüri osatäitjaks ekslikult nimetatud lavastuse osatäitjat Allan Noormetsa ( tegelikult Aivar Tommingas)
1998-01-01
21.5. esilinastuvad kinos "Sõprus" 6 animafilmi : "Vares ja hiired", autorid Priit Tender ja Mikk Rand; "Just märried", autor Peep Pedmanson; "Päevavalgus", autor Mait Laas; "Tom ja Fluffy", režissöörid Janno Põldma ja Heiki Ernits; "Bermuda", autor Ülo Pikkov; "Primavera", režissöörid Riho Unt ja Hardi Volmer. Aut. : M.R
Kes räägib tõtt, kes ebatõtt? / Elmar Truu
Truu, Elmar-Johannes, 1942-
2001-01-01
Ilmunud ka: Sakala, 27. nov. 2001, lk. 2; Meie Maa, 28. nov. 2001, lk. 2; Valgamaalane, 27. nov, 2001, lk. 2; Virumaa Teataja, 28. nov. 2001, lk. 7; Nädaline, 29. nov. 2001, lk. 4; ERL Teataja, dets. 2001, nr. 12, lk. 4. Riigikogu 14. nov. infotunnis pöördumisest sotsiaalministri Eiki Nestori poole küsimustega ravimite hinna järjekindlast tõstmisest. Autor: ERL. Parlamendisaadik
Plaadid / Mait Eelrand, Toomas Puna, Veiko Pesur...[jt.
2007-01-01
Uutest heliplaatidest Wolf & Cub "Vessels", Karl MAdis & Karavan "Taevalik meloodia ئ Nat King Cole'i laule", Sophie Ellis-Bextor "Trip The Light Fantastic", Him "Uneasy Listening 1&2", Kognito "Muutuv"
Katse portreteerida nõukogude kosmosemaja / Mait Väljas
Väljas, Mait
2011-01-01
Prantsuse fotograafist Frédéric Chaubinist, kes pildistas NSV Liidus 1975.-1990. a. ehitatud eripäraseid hooneid, korraldas fotonäitusi. F. Chaubini raamatust "СССР : cosmic communist constructions photographed" (Köln : Taschen, 2011), raamatusse jõudnud eesti arhitektuurist
Rotermanni soolalao urbanistliku pargi ideekonkurss / Mait Väljas
Väljas, Mait
2009-01-01
Eesti Arhitektuurimuuseumi korraldatud avalikust konkursist, Ignar Fjuki koostatud võistlustingimustest, premeeritud töödest. 1. preemia sai töö "Piazza", autor Villem Tomiste, (AB Kosmos)), 2. preemia töö "Muesuum", autor Ott Kadarik, (AB Kosmos), 3. preemia töö "Arhitektuuri allee", autor Jürgen Lepper, (AB Dimensioon). Anti välja üks ergutuspreemia, ära märgiti kaks tööd
Teadusmõtte ja teaduse mineviku lood / Mait Talts
Talts, Mait, 1964-
2011-01-01
Arvustus: Baltic Journal of European Studies. Selected papers of the 24th International Baltic Conference on the history of science and the follow-up seminar (2011, nr. 1). Tallinn : Tallinn University of Technology, 2011
Karl Menningu (ja iseenese) päästmiseks / Ants Hein
Hein, Ants, 1952-
2008-01-01
Vastuseks Karin Hallas-Murula arvustusele "Maja, mis on sümbol" (Sirp, 2007, 5. X, lk. 13) ja Mait Väljase arvustusele "Iseolemise algus arhitektuuris" (Maja, 2008, nr. 1, lk. 86-87) oma 2007. a. ilmunud raamatust "Maja kui sümbol : Eesti Üliõpilaste Seltsi hoone Tartus" kohta. Georg Hellati ja Karl Menningu osalusest EÜS-i hoone sünniloos. Frank Lloyd Wrightist kui võimalikust eeskujuandjast
La persona feliz : personalidad, bienestar psicológico subjetivo y variables predictoras
Martín Martín, Carla
2015-01-01
El propósito de este trabajo es realizar una réplica del estudio de Maite Garaigordobil, Jone Aliri e Iraide Fontaneda, titulado “Bienestar Psicológico Subjetivo: diferencias de sexo, relaciones con dimensiones de personalidad y variables predictoras”(2009). En dicho trabajo, analizan diferentes variables en relación al bienestar psicológico subjetivo, exploran las relaciones del bienestar psicológico y el material con las dime...
Epner, Pille
2013-01-01
Arhitektuurikonkursist, võidutööst "Fiat Lux" (arhitektid Risto Parve, Kai Süda, Martin Kinks, Margit Valma, arhitektuuriteadlane Mait Väljas, Karisma Arhitektid), 2. koha pälvinud tööst "Õhuke Koht" (Pille Noole, Üllar Ambos, Kaisa Lasner, Kerttu Karjust, Jiannis Lykouras, Arhitektuurinurk), 3. koha pälvinud tööst "Tee" (Villem Tomiste, Stuudio Tallinn). Loetletud ostupreemia ja kolm tunnustuse pälvinud võistlustööd
Barbarid, plastiliinijänes, Miriam ja Frank Muller / Annika Koppel
Koppel, Annika
2003-01-01
Nukufilm näitab 4 uut filmi : "Barbarid" (stsenaristid Andrus Kivirähk ja Hardi Volmer, režissöör H. Volmer), "Porgand" (stsenarist Peep Pedmanson, režissöör Pärtel Tall), "Miriami jõulupäkapikk" (stsenaristid Leelo Tungal ja Peep Pedmanson, režissöör Mait Laas), "Kuuvaatleja" (reklaamitreiler Frank Mulleri kellafirmale ; stsenarist, režissöör, kunstnik Mati Kütt)
Modernistlik ruumikontseptsioon ja nõukogude ideoloogia kohtuvad Viru hotellis / Karen Jagodin
Jagodin, Karen, 1982-
2006-01-01
Ajavahemikul 1964-1968 arhitektide Henno Sepmanni ja Mart Pordi poolt projekteeritud ning 1972. a. valminud Viru hotellist Tallinnas, põhjalikum ülevaade hoone interjöörist. Sisearhitektid Väino Tamm, Vello Asi, Taevo Gans, Mait Summatavet ja Loomet Raudsepp. II korruse naiste juuksuri ruumid kujundas Kirsti Laanemaa. II korruse banketisaalis oli Mari Adamsoni gobelään "Tare", suures restoranisaalis Aet Andresma-Tamme ja Mare Soovik-Lobjakase klaaskompositsioon "Pilved", Viru väljakul Edgar Viiese skulptuur "Merepiiga" (1981)
Põhjamaade põlisvähemuste omakeelsest meediast / Mait Talts
Talts Mait, 1964-
2009-01-01
Artikkel jätkab Läänemere-äärsete etniliste vähemuskultuuride käsitlust. Vt. ka Haridus 5/6 2008, "Põlisvähemuskultuuride meediamaastikult" (latgalite, liivlaste, karaiimide, väikeleedulaste, kašuubide jt. omakeelse meedia hetkeolukorrast ja arenguperspektiividest)
Wallenbergide Investor jätkab kasvustrateegiat / Olev Mait Makk
Makk, Olev Mait
2001-01-01
Wallenbergide kontrollitavast Rootsi investeerimisfirmast Investor, mille omanduses olevad firmad moodustavad kokku Euroopa suurima tööandja erasektoris. Investori gruppi kuuluvast ettevõttest SEB. Tabel: Investori portfellis olevad aktsiad; investori teenused tütarettevõtetele
The singing revolution : part II-III / Mait Ando Raun
Raun, Mait, 1963-
2000-01-01
Tartu rahu ja vabariigi aastapäeva tähistamisest 1988. aastal; Sündmused veebruarist aprillini 1988: üliõpilaste demonstratsioonist veebruaris, Loominguliste Liitude ühispleenumist, Rahvarinde loomisest ja Tartu muinsuskaitsepäevadest aprillis. Järg nr.4, lk.70-73
Ma olen Turist, ma elan siin / Mait Väljas
Väljas, Mait
2006-01-01
Endise valuutapoe, praeguse klubi "Parlament" lammutamisplaanist Tallinnas Tartu mnt. 17. Arhitektid Peep Jänes ja Henno Sepmann, sisearhitekt Toivo Gans, sisekujundaja Aulo Padar. Ehitamisel osalesid ka soome arhitektid Kalle-Heiki Narinen ja Tapio Hänninen. Kommentaar Peep Jäneselt ja Aulo Padarilt
1987-04-01
Is Defense, en alant au-doll de ce qua peut apporter un simple repertoire, commae celul du DTIC aux Etats-Unis (5). ii counvient donc de dhvelopper...en consultation mais devront etre exclus du prit. Maits touts laide qua h’on apportersa Al’utilisaeur, celul -ci perdra besucoup do tampa I cee...mains quoun systme do guichat ivolui. come celul dont il a iti question plus haut, soit jug& prifirable. 8-5 2.3. Sources primaires. Touts information
Olulised on kokkulepped Euroopa vaesema ja rikkama osa vahel / Viktor Sartakov ; interv. Tiia Truu
Sartakov, Viktor, 1947-
2002-01-01
Eestimaa Tootjate Keskliidu juhatuse esimees Viktor Sartakov osalemisest Kopenhaagenis EL-i Põllumajandusorganisatsioonide Komitee (COPA) ja Põllumajandusühistute Peakomitee (COGECA) toimkondade töös, EL-i liikmesmaade suhtumisest kandidaatriikidesse, EL-iga liitumise kasust, ohtudest
Hogg, Robert; Hogg, Robert; Hart, Trevor; Tan, Darrell; Hart, Trevor; Tan, Darrell; Boily-Larouche, Genevi?ve; Lajoie, Julie; Omollo, Kenneth O; Cheruiyot, Julianna; Njoki, Jane; Kimani, Makubo; Oyugi, Julius; Kimani, Joshua; Fowke, Keith R
2015-01-01
BACKGROUND: The C-type lectin CD161 is expressed by CD4+ and CD8+ T cells sharing conserved transcriptional and functional signature. CD4+ T cells with type-17 profiles derived from CD161+ precursors and CD161-expressing CD8+ T cells share the same differentiation profile and include the unique anti-bacterial CD161++ mucosal-associated invariant T cells (MAIT) expressing invariant TCR V?7.2. During HIV infection, circulating cells harbouring the signature of CD161+ cells are impaired in blood...
Eesti teatri aastaauhinnad 2001
2002-01-01
Lavastajaauhind Hendrik Toompere, meesnäitleja Mait Malmsten, naisnäitleja Kersti Kreismann, meeskõrvalosatäitja Sulev Teppart, naiskõrvalosatäitja Kersti Tombak, kunstnikupreemia Ene-Liis Semper, eriauhind Marko Matvere, tantsulavastuse auhind Age Oks, Toomas Edur, Katrin Essenson, kriitikuauhind Reet Neimar ja Lea Tormis, Ants Lauteri preemia Katariina Lauk-Tamm ja Andres Raag, Salme Reegi auhind VAT Teater, Priit Põldroosi preemia Ingo Normet, Aleksander Kurtna preemia Tõnu Oja ja Villu Kangur, Georg Otsa preemia Pille Lill, muusikalavastuse auhind Mati Palm, muusikalavastuse eriauhind Teo Maiste
Finskii grafitsheskii beton teper takzhe i v Estonii / Mait Eelrand
Eelrand, Mait
2007-01-01
Graafilise betooni meetodi arendas 1990. aastate lõpul välja soome sisearhitekt Samuli Naamanka, tehnoloogia on patenteerinud tema asutatud firma Graphic Concrete Oy. AS E-Betoonelement kasutas graafilise betooni tehnoloogiat esimesena Rakveres büroohoone fassaadi kujundamiseks. Kommenteerivad Graphic Concrete Oy tegevdirektor H. Lanningu ja K. Meus AS-st E-Betoonelement
Oluline teatmeteos, mis võinuks olla veelgi parem / Mait Talts
Talts, Mait, 1964-
2010-01-01
Arvustus: Eesti perioodika 1941-1944 = Estnische Periodika 1941-1944 = Periodicals in Estonia 1941-1944 = Эстонская периодика 1941-1944 / Eesti Rahvusraamatukogu ; koostanud Külli Kaunissaar. Tallinn, 2009. (Eesti retrospektiivne rahvusbibliograafia)
Truu, Mario, 1989-
2017-01-01
Riigikohtu kriminaalkolleegiumi otsusest asjas 3-1-1-111-16, teo toimepanija tahtlusest raske tervisekahjustuse tekitamise katse korral. Tervisekahjustuse liigi ja raskuse tuvastamisest kriminaalkohtumenetluses
Üheksa ametit kindlasti, aga kümnes nälg ei ole / Tiia Truu
Truu, Tiia, 1948-
2009-01-01
Raplamaa käsitööseltsingu "Süstik" juhatuse esimehest Ivi Sargast ja tema tegemistest. Ivi Sark on lõpetanud Tartu Ülikooli kehakultuuriteaduskonna, tegeleb lapitööga, on tuntud laatade ja teiste ürituste korraldajana, 2007. aastast on Järvakandi gümnaasiumis käsitöö- ja võimlemisõpetaja
Presidendi taluehitaja mängib võlausaldajatega peitust / Ingvar Bärenklau
Bärenklau, Ingvar, 1967-
2007-01-01
President Toomas Hendrik Ilvese ja proua Evelin Ilvese Ärma talus ehitustöid korraldanud ning alltöövõtjatele võlgu jäänud Aus Invest OÜ omanikud Aivar ja Mait Aus on läinud võlausaldajate eest peitu Norrasse ning kirjutanud oma vara teiste isikute nimele. Vt. samas: Presidenditalu rahavaidlus. Aus Invest on jätnud tasumata maaparandus- ja pinnasetöödefirmale AS Nuia Melior ja Pärnu puidutööstusele AS Puit. Proua Evelin Ilvese kinnitusel on Ärma talu omanikfirma Ermamaa Aus Investile kui peatöövõtjale kõik arved tasunud
Soomlaste graafiline betoon nüüd ka Eestis / Mait Eelrand
Eelrand, Mait
2007-01-01
Graafilise betooni meetodi arendas 1990. aastate lõpul välja soome sisearhitekt Samuli Naamanka, tehnoloogia on patenteerinud tema asutatud firma Graphic Concrete Oy. AS E-Betoonelement kasutas graafilise betooni tehnoloogiat esimesena Rakveres büroohoone fassaadi kujundamiseks. Kommenteerivad Graphic Concrete Oy tegevdirektor H. Lanningu ja K. Meus AS-st E-Betoonelement
Mait Müntel lahendab teaduse suurt ristsõna / intervjueerinud Kristi Helme
Müntel, Mait
2010-01-01
Intervjuu keemilise ja bioloogilise füüsika instituudi noore teadlasega, kes pälvis Vabariigi Presidendi Kultuurirahastu noore teadlase preemia. Ta on kaitsnud doktoritöö teemal „Topeltlaetud Higgsi bosoni detekteerimine CMS-i detektoril”
Ettevõtte konkurentsieelis inimeste analüüsi abil / Mait Raava
Raava, Mait
2015-01-01
Ettevõtte töötajate analüüsimisest, analüütika tulemuste rakendamisest juhtivates ettevõttes. Viiest sambast, millel põhineb inimeste analüüsi edukas rakendamine, analüütika rakendamise etapid
Tagasisidet peab töötajale vahendama ülemus / Mait Raava
Raava, Mait
2004-01-01
Autor teeb lühiülevaate 360ʻ ja teiste tagasiside meetodite rakendamisest maailmas alates 1950ndatest aastatest ning juhib tähelepanu vigadele, mida meetodi rakendamisel on tehtud. Kommenteerib Irene Metsis. Skeem: Juht saab tagasiside nelja kanali kaudu. Vt. samas: Rollist tulenevalt on tagasiside erinev
Kulu- ja turupõhisest hinnakujundamise strateegiast turunduses / Mait Miljan, Kalev Kaarna
Miljan, Mait
2005-01-01
Tänapäevases ärikeskkonnas soovitavad autorid kasutada kombineeritud mudelit, milles rakendatakse kulu- ja turupõhist strateegiat lähtuvalt ettevõtte turusituatsioonist, tegevusvaldkonnast ning püütakse liikuda ühtse hinnakujundamiseni tarneahelas kui tervikus. Skeemid
300 MWe Burner Core Design with two Enrichment Zoning
International Nuclear Information System (INIS)
Song, Hoon; Kim, Sang Ji; Kim, Yeong Il
2008-01-01
KAERI has been developing the KALIMER-600 core design with a breakeven fissile conversion ratio. The core is loaded with a ternary metallic fuel (TRU-U-10Zr), and the breakeven characteristics are achieved without any blanket assembly. As an alternative plan, a KALIMER-600 burner core design has been also performed. In the early stage of the development of a fast reactor, the main purpose is an economical use of a uranium resource but nowadays in addition to the maximum utilization of a uranium resource, the burning of a high level radioactive waste is taken as an additional interest for the harmony of the environment. In way of constructing the commercial size reactor which has the power level ranging from 800 MWe to 1600 MWe, the demonstration reactor which has the power level ranging from 200 MWe to 600 MWe was usually constructed for the midterm stage to commercial size reactor. In this paper, a 300 MWe burner core design was performed with purpose of demonstration reactor for KALIMER-600 burner of 600 MWe. As a means to flatten the power distribution, instead of a single fuel enrichment scheme adapted in design of KALIMER-600 burner, the 2 enrichment zoning approach was adapted
Gaudenzi, P.; Atek, S.; Cardini, V.; Eugeni, M.; Graterol Nisi, G.; Lampani, L.; Pasquali, M.; Pollice, L.
2018-05-01
In this paper the AM-induced evolution of the design process for small satellites is investigated, leading to the identification of optimal design strategies and the definition of a new MAIT concept. A review of the open literature is presented and some introductory concepts are exposed to highlight the effect of the introduction of AM technologies in the development of new satellites systems. In particular, an innovative structural configuration for the CubeSat class of satellites is proposed, with the ultimate goal of minimizing system complexity via parts reduction and the integration of subsystems through an innovative assembly configuration, as an example to be considered for larger satellites.
2008-01-01
AS Nord Projekt; konstruktorid: Juhan Idnurm, Jaan Port, Kaido Kuusiku (Nord Projekt AS), Indrek Heinloo (E-Inseneribüroo OÜ), Matis Teeäär (Neoprojekt OÜ), Kaido Pärl (TAA-Konsult); ehitajad: Lemminkäinen Eesti AS, AS Merko Ehitus; betooni ja betoonelementide tarnijad: AS Rudus Eesti, AS Betoneks
NOMAD on the ExoMars TGO 2016 mission: MAIT and characterisation testing
Vandaele, Ann C.; Neefs, Eddy; Lopez-Moreno, J. J.; Rodriguez Gomez, Julio; Drummond, Rachel; Patel, Manish; Thomas, Ian; Gissot, Samuel; Depiesse, Cedric; Ben Moussa, Ali; Giordanengo, Boris; Bellucci, Giancarlo
NOMAD, the “Nadir and Occultation for MArs Discovery” spectrometer suite has been selected by ESA and NASA to be part of the payload of the ExoMars Trace Gas Orbiter mission 2016. This instrument suite will conduct a spectroscopic survey of Mars’ atmosphere in the UV, visible and IR regions covering the 0.2-0.65 and 2.2-4.3 μm spectral ranges. NOMAD’s observation modes include solar occultation, nadir and limb observations. The NOMAD instrument is composed of 3 channels: a solar occultation only channel (SO) operating in the infrared wavelength domain, a second infrared channel capable of observing nadir, solar occultation and limb observations (LNO), and an ultraviolet/visible channel (UVIS) that can work in all observation modes. The spectral resolution of SO and LNO surpasses previous surveys in the infrared by more than one order of magnitude. NOMAD offers an integrated instrument combination of a flight-proven concept (SO is a copy of SOIR on Venus Express), and innovations based on existing and proven instrumentation (LNO is based on SOIR/VEX and UVIS has heritage from the ExoMars lander), that will provide mapping and vertical profile information at high spatio-temporal resolution. The three channels have each their own ILS and optical bench, but share the same single interface to the S/C. The NOMAD flight model is due for delivery to ESA in January 2015. We will present results so far of the manufacturing, assembly and especially testing of the various components. The UV CCDs have been characterised in thermal-vacuum; optical fibres have been studied with UV exposure to look at transmission degradation; the IR AOTFs have been tested for their transfer functions; lifetime and vibration testing has been carried out on the flip mirror mechanism. These are all vital inputs to the scientific results from NOMAD. Acknowledgements - The research program was supported by the Belgian Federal Science Policy Office and the European Space Agency (ESA PRODEX program). IAA participation is funded by MICIIN through Plan Nacional Ref. AYA2009-08190. UVIS support provided by the Open University and partly by STFC. Italian participants acknowledge the support from ASI.
Kunstide sünesteesia. Tasapinnalise visuaali ja muusika suhted / Einike Leppik
Leppik, Einike
2010-01-01
Uuritakse ja analüüsitakse kunstide sünesteesia printsiipe, ajaloolist kujunemist ja seoseid kujutava kunsti ja muusika loomisel. Lähtutud on 20. sajandil alguse saanud ja tänapäevani kestvatest arengutest kunstis - kunsti piiride hägustumisest, laienemisest ning nähtustest, mis nende arengutega kaasas on käinud 1890-1960-ndateni. Tõmmatakse paralleele Kandinsky abstraktsete impressioonide ja Schönbergi atonaalse helikeele, Claude Monet' maalide ja Claude Debussy muusika vahel, Čiurlionise kui kunstniku ja muusiku fuugamaastike, Eric Satie sünesteetilise kunsti ja John Cage'i jt. loomingu vahel. Praktilise tööna on 33 joonistusest kokku pandud installatsioon "Joon", mille põhjal komponeeris muusika EMTA tudeng Mait Jüriado
Détection des symptômes anxieux et dépressifs en médecine générale
Bertin Persichini, Caroline
2015-01-01
Contexte : L’anxiété et la dépression sont des problèmes de santé publique. Ces troubles sont fréquents et il est indispensable de les diagnostiquer. Le diagnostic se fait principalement par les médecins généralistes et se base sur leur intuition.Objectif : L’objectif principal était d’établir la sensibilité et la spécificité des médecins généralistes dans la détection de l’anxiété et de la dépression, quelque soit le motif de consultation.Méthodes : Les médecins participants étaient des mait...
Türkei, Jüri
2016-01-01
Niguliste 6 on Tallinna vanalinnale omane mitmes järgus ehitatud kaupmeheelamu. 2015. aasta uuringute käigus avati uuesti kõik huvipakkuvad piikonnad. Taasavastati dornse paarisakna sillust toetanud paesammas, millel on voluutidest välja kasvav kuradinägu
Applying theory of constraints in tactical and strategic management / Kalev Kaarna, Mait Miljan
Kaarna, Kalev
2002-01-01
Bibliogr. lk. 86-87. - Kokkuvõte eesti keeles lk. 87. Piirangute teooria kasutamise vajadusest ja võimalustest. Piirangute juhtimisest pikas perspektiivis ning sellel põhinevast strateegilisest juhtimisest. Tabelid
Majad ja muutumised marsruudil JPN-USA-EST / Tomomi Hayashi ; intervjueerinud Mait Väljas
Hayashi, Tomomi, 1971-
2011-01-01
Intervjuu Jaapanis Toyamas sündinud ning Eestis elava ja töötava arhitekti Tomomi Hayashiga, kes aastast 2004 on HG Arhitektuur OÜ arhitekt ja partner. Endast, tööst New Yorgis Rafael Viñoly büroos, Eestisse tulekust, oma tööpõhimõtetest, lemmikarhitektidest, järgmisest ehitusbuumist jm. Loetletud T. Hayashi töid, preemiad
Turuanalüüs - eduka turunduse juhtimise üks võtmetegur / Mait Miljan
Miljan, Mait
2002-01-01
Ettevõtte turunägemuse kujundamisel puutub kokku selliste mõistetega nagu turu definitsioon, turu arenguindeks (Market - MDI), turupotentsiaal, turunõudlus, turuosa arenguindeks (Share Development Index - SDI). Diagrammid
Ärma talu ehitanud Aus Invest müüdi Panama riiulifirmale maha / Kadri Paas
Paas, Kadri, 1982-
2007-01-01
Ärma talu ehitanud Aus Invest OÜ ei ole maksnud tööde eest kõigile alltöövõtjatele. Proua Evelin Ilvese sõnul on Ermamaa peatöövõtjale kõigi kokkulepitud tööde eest maksnud. 2007. a. mais müüsid Aivar Aus ja Mait Aus Tartu maakohtu registriosakonna andmetel Aus Invest OÜ Panamal registreeritud riiulifirmale Arliana Enterprises Corp. Vt. samas: Nõunik sekkus presidendi teleintervjuusse. Kui telekanali TV3 Lõuna-Eesti reporter Valgamaal visiidil viibivalt Toomas Hendrik Ilveselt ja proua Evelin Ilveselt Ärma talu ehitusega kaasnenud võlgade kohta aru päris, sekkus kõnelusse presidendi avalike suhete nõunik Toomas Sildam. Vt. ka lk. 10: Urmo Soonvald. Ärma triibulised. Ajakirjanik ootab Ärma talu probleemidega seoses suuremat avalikustamist
Meduus Riia rannas / Galina Timtšenko ; intervjueerinud Mihhail Trunin ; tõlkinud Mait Eelrand
Timtšenko, Galina
2016-01-01
Intervjuu veebiväljaande Lenta.ru endise peatoimetaja, portaali Meduza looja ja peadirektori Galina Timtšenkoga veebilehest Meduza, ajakirjanduse arengusuundadest ning Baltimaades tegutsevate venekeelsete massiteabevahendite iseärasustest
Procedure for obtaining visas for Switzerland and France - Signature rights
2016-01-01
In accordance with the Status Agreements with CERN, Switzerland and France facilitate the entry of members of the Organization’s personnel on to their territories. Where relevant, detailed procedures for obtaining visas apply. Within the framework of those procedures, only the following individuals are authorised to initiate the Note verbale procedure as well as to sign the Official Invitation Letters and the Conventions d’accueil. Kirsti ASPOLA (EP – CMO) Maite BARROSO LOPEZ (IT – DI) Catherine BRANDT (DG – DI) Michelle CONNOR (TH – GS) Gaëlle DUPERRIER (EP – AGS) Patrick FASSNACHT (EP – ADO) Fernando FERNANDEZ SAVORGNANO (HR – TA) Nathalie GRÜB (EP – AGS) Laurie HEMERY (BE – ASR) Cécile NOELS (ATS – DO) Tania PARDO (EP – AGS) Maria QUINTAS (HR – TA) Kate RICHARDSON (EP – AGS) Jeanne ROSTANT (TH – GS)...
Tugeva kultuuriga firmas võetakse vastutust, nõrgas süüdistatakse teisi / Mait Raava
Raava, Mait
2005-01-01
Ilmunud ka: Delovõje Vedomosti 12. okt. lk. 39; Juhi ideelaegas. - Tallinn, 2006, lk. 10-13. Tugev organisatsioonikultuur suunab töötajaid raskuste korral pingutama, nõrk firmakultuur aga iseenda tagalat kindlustama ja teisi süüdistama
Overview of the M.A.I.T. analysis system (machine analysis of the internal threat)
International Nuclear Information System (INIS)
NiCastro, J.R.
1978-01-01
The problem of the internal threat epitomized by the tactics of collusion and illicit use of access has been structured into a data processing format. The format procedures and analysis are objective; the flexibility of the method allows the security analyst to input his judgment and opinions into the code. By so doing he can interact and determine the effects of interacting with the safeguard system
Kotas, Maya E; Locksley, Richard M
2018-06-19
Innate lymphoid cells (ILCs) are positioned in tissues perinatally, constitutively express receptors responsive to their organ microenvironments, and perform an arsenal of effector functions that overlap those of adaptive CD4 + T cells. Based on knowledge regarding subsets of invariant-like lymphocytes (e.g., natural killer T [NKT] cells, γδ T cells, mucosal-associated invariant T [MAIT] cells, etc.) and fetally derived macrophages, we hypothesize that immune cells established during the perinatal period-including, but not limited to, ILCs-serve intimate roles in tissue that go beyond classical understanding of the immune system in microbial host defense. In this Perspective, we propose mechanisms by which the establishment of ILCs and the tissue lymphoid niche during early development may have consequences much later in life. Although definitive answers require better tools, efforts to achieve deeper understanding of ILC biology across the mammalian lifespan have the potential to lift the veil on the unknown breadth of immune cell functions. Copyright © 2018 Elsevier Inc. All rights reserved.
DEFF Research Database (Denmark)
Vadstrup, Kasper; Bendtsen, Flemming
2017-01-01
with a wide range of cell types and proteins involved. Natural Killer Group 2D (NKG2D) is an activating receptor constitutively expressed on human Natural Killer (NK), γδ T, mucosal-associated invariant T (MAIT), CD56⁺ T, and CD8⁺ T cells. Activation of NKG2D triggers cellular proliferation, cytokine...... production, and target cell killing. Research into the NKG2D mechanism of action has primarily been focused on cancer and viral infections where cytotoxicity evasion is a concern. In human inflammatory bowel disease (IBD) this system is less characterized, but the ligands have been shown to be highly...... expressed during intestinal inflammation and the following receptor activation may contribute to tissue degeneration. A recent phase II clinical trial showed that an antibody against NKG2D induced clinical remission of CD in some patients, suggesting NKG2D and its ligands to be of importance...
1998-01-01
Pärnu filmipäevadel 'Do Re Vi' võitis Grand Prix ehk skulptuuri 'Oskar & Ella' reklaamistuudio 'Division', kullatud videokassetid said 'Polarfilm' (dok. film), Martin Pedanik (video) ja Edith Sepp ('Tingimustega Tallinnas'); osalejate M. Laasi, J. Lõhmuse, A. Visti ja I. Raagi kommentaare ürituse kohta;
Kangelane ja kaabakas: kuulsad kuningad muistse LähisIda ja Kreeka pärimustes / Mait Kõiv
Kõiv, Mait, 1961-
2015-01-01
Mesopotaamia, Pärsia ja Vana-Kreeka kolmest olulisest dünastiast. Akkadi kuningatest - Sargon'ist ja Naram-Sin'ist, Pärsia kuningatest Kyros'est ja Kambyses'est. Korintose türannidest Kypselos'est ja Periandros'est. Pärimuse tagamaadest: müütidest, propagandast ja reaalsusest. Dünastia rajaja kujutamisest kangelasena ja dünastia viimase esindaja demoniseerimisest
Selles töös oli kaks õudust : vangla ja tants / Mait Malmsten ; interv. Tiina Ansip
Malmsten, Mait
2005-01-01
Näitleja räägib oma tööst ja rollist rahvusvahelises ühistöös valminud tantsufilmis "Teine" ("Another") : režissöör Rene Vilbre : koreograaf ja peaoaline Helena Jonsdottir. Filmi võtted toimusid Tartu vanglas
Propuesta de programa para una Maestría en Arte e Investigación Teatral (MAIT)
Prado Zavala, Jorge
2015-01-01
En México (y Latinoamérica) ha habido pocos intentos para instrumentar posgrados en teatro, y pocos han persistido. En el pasado en México, la UNAM ya intentó construir un programa de maestría en teatro, pero no prosperó. Algunos estudios prefieren concentrarse en la creación, como el proyecto de Maestría en Dirección Escénica de la ENAT, con un antecedente directo en el CUT. Uno de los intentos más recientes es el programa de Maestría en Teatro de la Universidad Veracruzana, la que a partir ...
Makk, Olev Mait
2011-01-01
Intervjuu Cannes'is globaalsel kinnisvaramessil ja konverentsil MIPIM 2011 viibinud Seven Real Estate Advisors partneri, investeeringute ja nõustamisvaldkonna juhiga. Kinnisvara puhul on välisinvestorite poolt eelistatud sihtriik nn. uue Euroopa riikide seas Poola. Välisinvestorite suurim huvi Eestis on stabiilset rahavoogu tootvate büroo- ja kaubanduskeskuste vastu
Role of innate T cells in anti-bacterial immunity
Directory of Open Access Journals (Sweden)
Yifang eGao
2015-06-01
Full Text Available Innate T cells are a heterogeneous group of αβ and γδ T cells that respond rapidly (<2 hours upon activation. These innate T cells also share a non MHC class I or II restriction requirement for antigen recognition. Three major populations within the innate T cell group are recognized, namely Invariant NKT cells (iNKT; Mucosal associated invariant T cells (MAIT and gamma delta T cells. These cells recognize foreign/self-lipid presented by non-classical MHC molecules, such as CD1d, MR1 and CD1a.They are activated during the early stages of bacterial infection and act as a bridge between the innate and adaptive immune systems. In this review we focus on the functional properties of these 3 innate T cell populations and how they are purposed for antimicrobial defense. Furthermore we address the mechanisms through which their effector functions are targeted for bacterial control and compare this in human and murine systems. Lastly we speculate on future roles of these cell types in therapeutic settings such as vaccination.
Directory of Open Access Journals (Sweden)
Lucy Jane Walker
2013-08-01
Full Text Available The T cell co-receptor CD8αβ enhances T cell sensitivity to antigen, however studies indicate CD8αα has the converse effect and acts as a co-repressor. Using a combination of Thymic Leukaemia antigen (TL tetramer, which directly binds CD8αα, anti-CD161 and anti-Vα7.2 antibodies we have been able for the first time to clearly define CD8αα expression on human CD8 T cells subsets. In healthy controls CD8αα is most highly expressed by CD161 bright (CD161++ mucosal associated invariant T (MAIT cells, with CD8αα expression highly restricted to the TCR Vα7.2+ cells of this subset. We also identified CD8αα-expressing populations within the CD161 mid (CD161+ and negative (CD161- non-MAIT CD8 T cell subsets and show TL-tetramer binding to correlate with expression of CD8β at low levels in the context of maintained CD8α expression (CD8α+CD8βlow. In addition, we found CD161-CD8α+CD8βlow populations to be significantly expanded in the peripheral blood of HIV-1 and hepatitis B (mean of 47% and 40% of CD161- T cells respectively infected individuals. Such CD8αα expressing T cells are an effector-memory population (CD45RA-, CCR7-, CD62L- that express markers of activation and maturation (HLA-DR+, CD28-, CD27-, CD57+ and are functionally distinct, expressing greater levels of TNF-α and IFN-γ on stimulation and perforin at rest than their CD8α+CD8βhigh counterparts. Antigen-specific T cells in HLA-B*4201+HIV-1 infected patients are found within both the CD161-CD8α+CD8βhigh and CD161-CD8α+CD8βlow populations. Overall we have clearly defined CD8αα expressing human T cell subsets using the TL-tetramer, and have demonstrated CD161-CD8α+CD8βlow populations, highly expanded in disease settings, to co-express CD8αβ and CD8αα. Co-expression of CD8αα on CD8αβ T cells may impact on their overall function in-vivo and contribute to the distinctive phenotype of highly differentiated populations in HBV and HIV-1 infection.
Väljas, Mait
2015-01-01
Eesti kultuurkapitali aastapreemia 2013 Tartu Ülikooli Narva Kolledžile. Arhitektuuri sihtkapitali arhitektuuripreemia Viljandi Riigigümnaasiumile, arhitektuuri eripreemia Kukemõisa karjamõisale, sisearhitektuuripreemia Tallinna Ülikooli BFMi õppehoonele, maastikuarhitektuuripreemia Eesti Ajaloomuuseumi väliekspositsioonile "Klooga laager ja holokaust", innovatsioonipreemia Passion House moodulmajale, arhitektuurialase tegevuse preemia Triin Ojarile ja disainipreemia Matti Õunapuule roller Stigo eest
Tasakaalus tulemuskaardi sage viga on vääralt määratud näitajad / Mait Raava
Raava, Mait
2003-01-01
Tasakaalus tulemuskaart väljendab strateegiliste tulemusnäitajate põhjuslik-tagajärjelisi seoseid, kuid viga tuleb sageli nende tegurite määratlemisel, kirjutab autor. Skeem. Kommenteerib Sven Heil
7th Symposium on Computational Statistics
Lauro, N; Rizzi, A
1986-01-01
When dealing with the design or with the application of any technical system, which is not quite simple and trivial, one has to face to the problem to determine the allowable de viations of the system functions and the optimal vector of system parameter tolerances. The need for the solution of this problem is stimulated with various serious economic and maite nance aspects, between them the tendency to reach the minimal production cost, the maximal system operation reliability are the most frequent. Suppose that we are dealing with an system S, consisting of N components represented by the system parame ters xi' i = 1, 2 . . . N, which are arranged in certain structu re so, that the K, system functions F k' k = 1, 2 . . . IG , expres sing the considered system properties, fullfil the condition F-FO~ AF, /1/ \\'Ihere F = l F k} Ie is the set of the actual system functions, FO = lFOk}~ is the set of the nominal system functions and A F = l A F k 1(;. } is the set 0 f the a 11 0 w a b 1 e s emf y s t u ...
Design of an x-ray telescope optics for XEUS
Graue, Roland; Kampf, Dirk; Wallace, Kotska; Lumb, David; Bavdaz, Marcos; Freyberg, Michael
2017-11-01
The X-ray telescope concept for XEUS is based on an innovative high performance and light weight Silicon Pore Optics technology. The XEUS telescope is segmented into 16 radial, thermostable petals providing the rigid optical bench structure of the stand alone XRay High Precision Tandem Optics. A fully representative Form Fit Function (FFF) Model of one petal is currently under development to demonstrate the outstanding lightweight telescope capabilities with high optically effective area. Starting from the envisaged system performance the related tolerance budgets were derived. These petals are made from ceramics, i.e. CeSiC. The structural and thermal performance of the petal shall be reported. The stepwise alignment and integration procedure on petal level shall be described. The functional performance and environmental test verification plan of the Form Fit Function Model and the test set ups are described in this paper. In parallel to the running development activities the programmatic and technical issues wrt. the FM telescope MAIT with currently 1488 Tandem Optics are under investigation. Remote controlled robot supported assembly, simultaneous active alignment and verification testing and decentralised time effective integration procedures shall be illustrated.
DEFF Research Database (Denmark)
Ammitzbøll, Cecilie; Börnsen, Lars; Romme Christensen, Jeppe
2017-01-01
Upon chronic cigarette smoke exposure, inhaled antigens and irritants cause altered lung immune homeostasis. Circulating immune cells are affected, and smoking is associated with an increased risk of developing various disorders, including multiple sclerosis (MS). This study was conducted......-induced proliferation and cytokine secretion in smokers and nonsmokers in a cohort of 100 healthy individuals (HI). In addition, we analyzed immune cell subsets associated with smoking in 2 independent cohorts of patients with MS. In HI smokers compared with nonsmokers, we found increased blood cell counts...... to determine the impact of smoking on circulating immune cell subsets. Furthermore, we determined whether any smoking-associated changes were related to MS. With the use of flow cytometry, CFSE assays, and ELISpot assays, we analyzed circulating immune cell phenotypes and quantified antigen...
Study on integrated TRU multi-recycling in sodium cooled fast reactor CDFR
International Nuclear Information System (INIS)
Hu Yun; Xu Mi; Wang Kan
2010-01-01
In view of recently proposed closed fuel cycle strategy which would recycle the integrated transuranics (TRU) from PWR spent fuel in the fast reactors, the neutronics characteristics of TRU recycled in China Demonstration Fast Reactor (CDFR) are studied in this paper. The results show that loading integrated TRU to substitute pure Pu as driver fuel will mainly make the influence on sodium void worth and negligible effects on other parameters, and hence TRU recycling in CDFR is feasible from viewpoint of core neutronics. If TRU is multi-recycled, the variation of TRU composition depends on fuel types and the ratio of TRU and U when recycling. It is indicated that, when TRU is multi-recycled in CDFR with MOX fuel, the minor actinides (MA) fraction in TRU will firstly decrease to ∼7.24% (minimum) within 8 TRU recycle times and then slowly increase to ∼7.7% after 20 TRU recycle times; while when TRU is multi-recycled in CDFR with metal fuel (TRU-U-10Zr), the MA fraction in TRU will gradually approach to an equilibrium state with the MA fraction of ∼3.8%, demonstrating better MA transmutation effect in metal fuel core. No matter 7.7 or 3.8%, they are both lower than ∼10% in PWR spent fuel with burnup of 45 GWd/tU, which presents satisfying effect of MA amount controlling for TRU multi-recycling strategy. On the other hand, the corresponding recycling parameters such as TRU heat release and neutron emission rate are also much lower in metal fuel than those in MOX fuel. Moreover, TRU recycled in metal fuel will bring greater fissile Pu isotopes equilibrium fraction due to better breeding capability of metal fuel. Finally, it could be summarized that integrated TRU multi-recycling in fast reactor can make contributions to both breeding and transmutation, and such strategy is a prospective closed fuel cycle manner to achieve the object of effective control of cumulated MA amount and sustainable development of nuclear energy.
International Nuclear Information System (INIS)
Stepanenko, V.A.; Shtukaturova, A.S.; Yasnij, P.V.; AN Ukrainskoj SSR, Kiev. Inst. Problem Prochnosti)
1983-01-01
Results of investigaytion have been discussed ipto the effect of certain temperature-force factors on regularities in the formation of stretch zones during the crack initiation static and transition zones at crack jumps in the process of cyclic loading. The 15Kh2NMFA pressure vessel steel has been investigated. The steel fracture toughnesKub(Ic) has been determined testing s the specimens for excentric stretching or a bending through an angle. It has been shown that transition zones in a front of fatique cracks at the jump beginning and end are formed through the shift mechanism owing to the material separation along the maximum failure zone contour, i.e. along the plastic zone contour in a crack vertex. This is the mait difference of regularities in the formation of the transition zones during fatique crack jumps from stretching zones formed through the break-away mechanism of crack vertex bluntness during its static move. It is noted that a final conclusion on the mechanism of transition zone formation during fartique crack jumps allows one to perform systematic investigation into the plastic zone configuration in a fatique crack verteX and stereofractographic measurement of two identically conjugate jump surfaces on opposite fractures of the same samples
CD1 and mycobacterial lipids activate human T cells.
Van Rhijn, Ildiko; Moody, D Branch
2015-03-01
For decades, proteins were thought to be the sole or at least the dominant source of antigens for T cells. Studies in the 1990s demonstrated that CD1 proteins and mycobacterial lipids form specific targets of human αβ T cells. The molecular basis by which T-cell receptors (TCRs) recognize CD1-lipid complexes is now well understood. Many types of mycobacterial lipids function as antigens in the CD1 system, and new studies done with CD1 tetramers identify T-cell populations in the blood of tuberculosis patients. In human populations, a fundamental difference between the CD1 and major histocompatibility complex systems is that all humans express nearly identical CD1 proteins. Correspondingly, human CD1 responsive T cells show evidence of conserved TCRs. In addition to natural killer T cells and mucosal-associated invariant T (MAIT cells), conserved TCRs define other subsets of human T cells, including germline-encoded mycolyl-reactive (GEM) T cells. The simple immunogenetics of the CD1 system and new investigative tools to measure T-cell responses in humans now creates a situation in which known lipid antigens can be developed as immunodiagnostic and immunotherapeutic reagents for tuberculosis disease. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Immunology in the liver--from homeostasis to disease.
Heymann, Felix; Tacke, Frank
2016-02-01
The liver is a central immunological organ with a high exposure to circulating antigens and endotoxins from the gut microbiota, particularly enriched for innate immune cells (macrophages, innate lymphoid cells, mucosal-associated invariant T (MAIT) cells). In homeostasis, many mechanisms ensure suppression of immune responses, resulting in tolerance. Tolerance is also relevant for chronic persistence of hepatotropic viruses or allograft acceptance after liver transplantation. The liver can rapidly activate immunity in response to infections or tissue damage. Depending on the underlying liver disease, such as viral hepatitis, cholestasis or NASH, different triggers mediate immune-cell activation. Conserved mechanisms such as molecular danger patterns (alarmins), Toll-like receptor signalling or inflammasome activation initiate inflammatory responses in the liver. The inflammatory activation of hepatic stellate and Kupffer cells results in the chemokine-mediated infiltration of neutrophils, monocytes, natural killer (NK) and natural killer T (NKT) cells. The ultimate outcome of the intrahepatic immune response (for example, fibrosis or resolution) depends on the functional diversity of macrophages and dendritic cells, but also on the balance between pro-inflammatory and anti-inflammatory T-cell populations. As reviewed here, tremendous progress has helped to understand the fine-tuning of immune responses in the liver from homeostasis to disease, indicating promising targets for future therapies in acute and chronic liver diseases.
The Effect of Mercury Mining Activities on Oak Forest in the Almaden Area
International Nuclear Information System (INIS)
Villadoniga, M.; Sierra, M. J.; Millan, R.
2009-01-01
This scientific-technical report is the result of the research work carried out by Maite Villadoniga Garcia, to obtain the Master's Final Project, this has been developed at the Unit of Soil Degradation in the Department of Environment at CIEMAT. Two main reasons are important for the study of the vegetation in Almaden, firstly to ascertain the state in which they find the different landscapes surrounding the mine and secondly, it would be interesting to know the potential applications for recovery areas, degraded by this type of mining. This report presents the initial analysis of a natural area where there has not been activity related to mining of mercury, but their lithologic conditions and proximity to the mine of Almaden (within 3 km) make it a space in which they are both elevated mercury concentrations in soil (1.25 to 35.55 mg kg - 1) and plant species (Quercus ilex: 0.10-2.29 mg kg - 1; Pseudovernia sp. 1.10-21.06 mg kg - 1). We can conclude after this study that the natural vegetation of the area if they had been affected by years of mining, although not find any obvious signs of damage to these ecosystems and that different factors affect the uptake of mercury by of different species. (Author) 37 refs.
A Typical Immune T/B Subset Profile Characterizes Bicuspid Aortic Valve: In an Old Status?
Directory of Open Access Journals (Sweden)
Carmela R. Balistreri
2018-01-01
Full Text Available Bicuspid valve disease is associated with the development of thoracic aortic aneurysm. The molecular mechanisms underlying this association still need to be clarified. Here, we evaluated the circulating levels of T and B lymphocyte subsets associated with the development of vascular diseases in patients with bicuspid aortic valve or tricuspid aortic valve with and without thoracic aortic aneurysm. We unveiled that the circulating levels of the MAIT, CD4+IL−17A+, and NKT T cell subsets were significantly reduced in bicuspid valve disease cases, when compared to tricuspid aortic valve cases in either the presence or the absence of thoracic aortic aneurysm. Among patients with tricuspid aortic valve, these cells were higher in those also affected by thoracic aortic aneurysm. Similar data were obtained by examining CD19+ B cells, naïve B cells (IgD+CD27−, memory unswitched B cells (IgD+CD27+, memory switched B cells (IgD−CD27+, and double-negative B cells (DN (IgD−CD27−. These cells resulted to be lower in subjects with bicuspid valve disease with respect to patients with tricuspid aortic valve. In whole, our data indicate that patients with bicuspid valve disease show a quantitative reduction of T and B lymphocyte cell subsets. Future studies are encouraged to understand the molecular mechanisms underlying this observation and its pathophysiological significance.
Žemaitės feminizmas. Žemaitė’s Feminism
Directory of Open Access Journals (Sweden)
Dalia Čiočytė
2009-01-01
Full Text Available The biography of Julija Beniuševičiūtė-Žymantienė – Žemaitė (1845–1921, one of the greatest Lithuanian Realists, has got a broad accent of feminist activity. Some short stories written by Žemaitė express feminist ideas with publicistic pathos (In Town, „Mieste“, 1905, Mister Zigmantas, „Ponas Zigmantas“, and others. In her short story Eve („Ieva“ Žemaitė presents an interesting ironic interpretation of the biblical archetype. Žemaitė’s best literary visions of women’s infelicity varies the topos of a quiet / silent / silenced woman and interestingly imply some gap between feminist ideology and literary meaning. In the short stories The Daughter-in-Law („Marti“, 1896, They Didn’t Have a Good Mother („Neturėjo geros motinos“, 1895 the reason of misfortunes seems to be deeper than just women being oppressed by men in the patriarchal society. The patriarchal oppression of women is constructed as a metonymy of the philosophical evil. The short story Sutkai (1897 may be interpreted as a literary vision of a feminine utopia: woman’s identity here is defined rather as wholeness than “otherness”.
Energy Technology Data Exchange (ETDEWEB)
Villadoniga, M.; Sierra, M.J.; Millan, R.
2009-07-01
This scientific-technical report is the result of the research work carried out by Maite Villadoniga Garcia, to obtain the Master's Final Project, this has been developed at the Unit of Soil Degradation in the Department of Environment at CIEMAT. Two main reasons are important for the study of the vegetation in Almaden, firstly to ascertain the state in which they find the different landscapes surrounding the mine and secondly, it would be interesting to know the potential applications for recovery areas, degraded by this type of mining. This report presents the initial analysis of a natural area where there has not been activity related to mining of mercury, but their lithologic conditions and proximity to the mine of Almaden (within 3 km) make it a space in which they are both elevated mercury concentrations in soil (1.25 to 35.55 mg kg{sup -}1) and plant species (Quercus ilex: 0.10-2.29 mg kg{sup -}1; Pseudovernia sp. 1.10-21.06 mg kg{sup -}1). We can conclude after this study that the natural vegetation of the area if they had been affected by years of mining, although not find any obvious signs of damage to these ecosystems and that different factors affect the uptake of mercury by of different species. (Author) 37 refs.
Energy Technology Data Exchange (ETDEWEB)
Villadoniga, M; Sierra, M J; Millan, R
2009-07-01
This scientific-technical report is the result of the research work carried out by Maite Villadoniga Garcia, to obtain the Master's Final Project, this has been developed at the Unit of Soil Degradation in the Department of Environment at CIEMAT. Two main reasons are important for the study of the vegetation in Almaden, firstly to ascertain the state in which they find the different landscapes surrounding the mine and secondly, it would be interesting to know the potential applications for recovery areas, degraded by this type of mining. This report presents the initial analysis of a natural area where there has not been activity related to mining of mercury, but their lithologic conditions and proximity to the mine of Almaden (within 3 km) make it a space in which they are both elevated mercury concentrations in soil (1.25 to 35.55 mg kg{sup -}1) and plant species (Quercus ilex: 0.10-2.29 mg kg{sup -}1; Pseudovernia sp. 1.10-21.06 mg kg{sup -}1). We can conclude after this study that the natural vegetation of the area if they had been affected by years of mining, although not find any obvious signs of damage to these ecosystems and that different factors affect the uptake of mercury by of different species. (Author) 37 refs.
2010-01-01
Vestlus Eesti muusika- ja teatriakadeemia lavakunstikooli XXIV lennu tudengitega, kelle lõputöö Tom Stoppardi näidend "Arkaadia" etendub Ugala laval. Lisatud Ugala teatri kirjandustoimetaja arvamus
Mälksoo, Lauri, 1975-
2011-01-01
17. mail 2010 tegi Euroopa Inimõiguste Kohtu suurkoda otsuse asjas Kononov vs. Läti, otsustades, et Läti ei rikkunud Euroopa inimõiguste ja põhivabaduste kaitse konventsiooni artiklit 7, kui mõistis Vassili Kononovi süüdi Teise maailmasõja ajal Lätis toimepandud sõjakuriteos
Žanr : suvelavastus? / Jaak Allik
Allik, Jaak, 1946-
2007-01-01
Kahekümnest suvisest teatriõhtust: Carlo Gozzi "Ronk" Tallinna Linnateatri lavaaugus (lavastaja Elmo Nüganen), Komöödiateatri suvetuuri lavastus "Elu parim puhkus" (lavastaja Ago-Endrik Kerge), muusikal "Tutvumiskuulutus" (lavastaja Mait Malmsten), Bernard Kangermanni laulumäng "Naabri Mari" (lavastaja Margus Vaher) ja Mara Zalite "Sirelikassid" (lavastaja Peeter Tammearu) Ugalas, Paul Barzi komöödia "Võimalik kohtumine" (lavastaja Raivo Trass) Vanemuise teatri suvelavastus Muhumaal Pädaste mõisas, muusikaline estraadietendus "Tähtede sadu", Endla "Tsirkus!!!" Paikuse-Reiu vabaõhulaval (autor ja lavastaja Tiit Palu), Andrus Kivirähki näidend "Uljas Neitsi" Laulasmaa Resort' rannametsas (lavastaja Taavi Teplenkov), Marti Kivastik "Eesti asi" (lavastaja Ingomar Vihmar) MTÜ Ühendus R.A.A.A.M. Viinistu kunstimuuseumi vabaõhulaval, Emajõe Suveteatri suvelavastus "Jumalaema kiriku kellamees" Victor Hugo romaani järgi (lavastaja Andres Dvinjaninov), "Muna EÜE ehk Viimane kava" (autor Lauri Vahtre, lavastaja Andrus Vaarik) Suure Munamäe vabaõhulaval, Aino Kalda "Reigi õpetaja" Kuressaares (lavastaja ja dramatiseerija Aare Toikka), Vana Baskini Teateris Pierre Chesnot "Kes aevastas?" (lavastaja Eino Baskin), Eduard Vilde romaani "Prohvet Maltsvet" ja vene kirjaniku Viktor Pelevini romaani aineil sündinud lavastus "Proffet" Albu vallas Kukenoosi rehealuses (lavastaja Mart Koldits), Enn Vetemaa "Roosiaed" Raasiku vallas Kiviloo mõisas (lavastaja Eva Klemets), Jim Ashilevi "Portselansuits" (lavastaja Lauri Lagle) Eesti Teatriliidu saalis, Andres Keili "Rooside sõda" Leigo Järveteatris (lavastaja Tõnu Lensment), Võru Teatriateljee suvelavastus Madis Kõivu "Castrozza ehk illusionist" (lavastaja Taago Tubin), Villu Tamme "Haned võlgu" (lavastaja ja kunstnik Jaanika Juhanson) Teatrilabor Von Krahli teatris
Aasta 1998 Tallinna Pedagoogikaülikoolis : [kroonika] / koost. Merike Määrits
1999-01-01
Ülevaateartikkel TPÜ tähtsamatest sündmustest 1998.a. ja lõpetajate nimekiri. 13. märtsil̀98 toimus filoloogiateaduskonnas emakeelepäev. 29.apr.̀98 parafraseerisid Roueni ülikool ja TPÜ koostöö põhiprintsiibid. 5. mail̀98 korraldas TPÜ rektoraat vastuvõtu Eesti meistrivõistluste II koha saanud korv- ja võrkpallinaiskonnale. 4. nov.̀98 avati TPÜ filoloogiateaduskonnas slavistika kabinet. 7., 8. mail̀98 toimus TPÜ kultuuriteaduskonna korraldusel teaduskonverents "Eesti kultuur 1940. aastate teisel poolel". 28. jaan.̀98 avati TPÜs Euroopa Ülikoolide Infokeskus. 2. sept.̀98 avati TPÜ Haapsalu Kolledž. 5. okt.̀98 tähistat TPÜ-s õpetajate päeva. EV presidendi vastuvõtul käisid 1998.a. TPÜ cum laude lõpetanud üliõpilased. 3. dets.̀98 korraldas TPÜ rektor Mait Arvisto vastuvõtu ülikooli üliõpilaste teadustööde konkursi võitjatele ja nende juhendajatele. 27. veebr.̀98, sotsiaalteaduskonna päeval anti teaduskonna õppejõududele üle õppejõupreemid. 16. okt.̀98 tähistati piduliku aktusega TPÜ 79. aastapäeva. TPÜ lõpetajad 1998. 7.-8.dets.̀98 korraldas TPÜ sotsiaaltöö osakond koostöös sotsiaalministeeriumi vanuripoliitika komisjoniga konverentsi "Ühiskond igale eale". EV haridusministeeriumi poolt korraldatud üliõpilaste teadustööde konkursil tunnistati Reimo Rivise töö ama alagrupis III preemia vääriliseks, diplomid said Krista Kalberg, Mihkel Märtin, Maris Pallas, Kaire Parts, Merle Talvik. 16. dets.̀98 avasid Prantsusmaa suursaadik Jacques Subrenat ja kultuuriatašee Catherine Suard prantsuse keele lektoraadi
Shakespeare, William, 1564-1616
2006-01-01
Sisu: "Kes kaunis on, peab andma vastse võsu..." ; "Sa peeglist näed: need palgejooned nüüd..." ; "Seesama aeg, mis kunstipeenelt voolib..." ; "Miks muusika teeb nukraks sind, kes ise..." ; "Ei, armastust ei tunne sinu rind..." ; "Nii ruttu, kui sa hääbud, uueks sirgud..." ; "Kui kuulen, kuidas aega mõõdab kell..." ; "Kuid miks sa ise tõhusamal moel..." ; "Kas suvepäeva sarnaseks sind kiita?..." ; "Aeg, õgard, küüned lõvil tömbiks kääna... ; "Ei veena peegel mind, et olen vana..." ; "Just nagu näitleja, kel kinni keel..." ; "Mu silm kui taidur võttis pilti teha..." ; "Mu armu isand, kelle truu vasall..." ; "Ma reisist väsinuna heidan sängi..." ; "Kui õnnest hüljatuna nutan sala..." ; "Kui vaikse leebe mõtte kohtu ette..." ; "Ma olen näinud küll, kuis tõusev päike..." ; "Ma tunnistan, et meid on siiski kaks..." ; "Nii nagu isa, vanadusest nõrka..." ; "Kui sulen laud, mu silmad hästi näevad..." ; "Nii ränk on reisida mul tüütul teel..." ; "Mis on su olemus, mis tuum su, miks..." ; "Ei kuningate uhked marmorsambad..." ; "Arm, uuenda end, nii et öelda sust..." ; "Kui uut ei olegi, vaid kõik on sama..." ; "Nii nagu lained ulgumerelt randa..." ; "Neiks päeviks, kui kord aeg mu armsal palge..." ; "Et näen, kuis aja käsi kõike lõhub..." ; "Kui pronksi, kivi, maad ja merd võib neelda..." ; "Mu tusk on ränk, nüüd surma kutsuks küll..." ; "Kui suren, ära leina mind sa kaua..." ; "Sa minus seda aastaaega näed..." ; "Mul sinust kirjutades arg on meel..." ; "Oo hüvasti! Liig kallis mul su hind..." ; "Siis vihka mind, kui pead, ja kohe praegu..." ; "Mõnd uhkeks teeb ta kunst, mõnd sünnipära..." ; "Sust eemal olin kevadel, mu arm..." ; "Kui möödaläinud aja kroonikais..." ; "Mis on veel ajul paberile kanda..." ; "Jah, tõsi, olen käinus siin ja seal..." ; "Ma uskuda ei saa, et murda suudab..." ; "On parem olla halb kui halvaks peetud..." ; "Ei, aeg, sa ära hoople, et mind muudad..." ; "Mu muusika, kui muusikat sa teed
Directory of Open Access Journals (Sweden)
Maria A Johansson
2016-07-01
Full Text Available Lactobacilli are probiotic commensal bacteria and potent modulators of immunity. When present in the gut or supplemented as probiotics, they beneficially modulate ex vivo immune responsiveness. Further, factors derived from several lactobacilli strains act immune regulato-ry in vitro. In contrast, Staphylococcus aureus (S. aureus is known to induce excessive T cell activation. In this study we aimed to investigate S. aureus-induced activation of human muco-sal associated invariant T cells (MAIT cells, γδ T cells, NK cells, as well as of conventional CD4+ and CD8+ T cells in vitro. Further, we investigated if lactobacilli-derived factors could modulate their activation.PBMC were cultured with S. aureus 161:2 cell free supernatant (CFS, staphylococcal en-terotoxin A or CD3/CD28-beads alone or in combination with Lactobacillus rhamnosus (L. rhamnosus GG-CFS or Lactobacillus reuteri (L. reuteri DSM 17938-CFS, and activation of T and NK cells was evaluated. S. aureus-CFS induced IFN-γ and CD107a expression as well as proliferation. Co-stimulation with lactobacilli-CFS dampened lymphocyte activation in all cell types analysed. Pre-incubation with lactobacilli-CFS was enough to reduce subsequent activation and the ab-sence of APC or APC-derived IL-10 did not prevent lactobacilli-mediated dampening. Final-ly, lactate selectively dampened activation of unconventional T cells and NK cells. In summary, we show that molecules present in the lactobacilli-CFS are able to directly dampen in vitro activation of conventional and unconventional T cells and of NK cells. This study provides novel insights on the immune modulatory nature of probiotic lactobacilli and suggests a role for lactobacilli in modulation of induced T and NK cell activation.
Abatement of CO{sub 2} emissions in the European Union
Energy Technology Data Exchange (ETDEWEB)
Lesourne, J.; Keppler, J.H.; Jaureguy-Naudin, Maite; Smeers, Yves; Bouttes, Jean-Paul; Trochet, Jean-Michel; Dassa, Francois; Neuhoff, Karsten
2008-07-01
This first monograph of the Ifri program on European Governance and Geopolitics of Energy is devoted to the control of carbon dioxide emissions within the European Union. Since it is almost unanimously accepted that Greenhouse Gas emissions constitute the main cause of the observed increase of the world average temperature, the system implemented by the European Union to limit and decrease the CO{sub 2} emissions is a significant pillar of the EU energy policy, the two others being the acceptance by the Member States of long-term commitments (for instance on the future share of renewable energy sources in their energy balance sheet) and the establishment of an internal market for electricity and gas. Though simple in principle, the European Union Greenhouse Gas Emission Trading Scheme (EU ETS) is in fact rather complex, and only experts really understand its merits and its deficiencies. These deficiencies are real and will have to be corrected in the future for the system to be effective. At this moment, when the 2005-2007 trial phase of the EU ETS is ending, the monograph has the purpose to stimulate the discussion between experts and to enable all those interested in the topic to understand the issues and to take part in the public debates on the subject. The monograph contains five papers: - 'An Overview of the CO{sub 2} Emission Control System in the European Union' by Jacques Lesourne and Maite Jaureguy-Naudin. - 'Description and Assessment of EU CO{sub 2} Regulations' by Yves Smeers. - 'Assessment of EU CO{sub 2} Regulations' by Jean-Paul Bouttes, Jean-Michel Trochet and Francois Dassa. - 'Investment in Low Carbon Technologies, Policies for the Power Sector' by Karsten Neuhoff. - 'Lessons Learned from the 2005-2007 Trial Phase of the EU Emission Trading System' by Jan Horst Keppler
Abatement of CO2 emissions in the European Union
International Nuclear Information System (INIS)
Lesourne, J.; Keppler, J.H.; Jaureguy-Naudin, Maite; Smeers, Yves; Bouttes, Jean-Paul; Trochet, Jean-Michel; Dassa, Francois; Neuhoff, Karsten
2008-01-01
This first monograph of the Ifri program on European Governance and Geopolitics of Energy is devoted to the control of carbon dioxide emissions within the European Union. Since it is almost unanimously accepted that Greenhouse Gas emissions constitute the main cause of the observed increase of the world average temperature, the system implemented by the European Union to limit and decrease the CO 2 emissions is a significant pillar of the EU energy policy, the two others being the acceptance by the Member States of long-term commitments (for instance on the future share of renewable energy sources in their energy balance sheet) and the establishment of an internal market for electricity and gas. Though simple in principle, the European Union Greenhouse Gas Emission Trading Scheme (EU ETS) is in fact rather complex, and only experts really understand its merits and its deficiencies. These deficiencies are real and will have to be corrected in the future for the system to be effective. At this moment, when the 2005-2007 trial phase of the EU ETS is ending, the monograph has the purpose to stimulate the discussion between experts and to enable all those interested in the topic to understand the issues and to take part in the public debates on the subject. The monograph contains five papers: - 'An Overview of the CO 2 Emission Control System in the European Union' by Jacques Lesourne and Maite Jaureguy-Naudin. - 'Description and Assessment of EU CO 2 Regulations' by Yves Smeers. - 'Assessment of EU CO 2 Regulations' by Jean-Paul Bouttes, Jean-Michel Trochet and Francois Dassa. - 'Investment in Low Carbon Technologies, Policies for the Power Sector' by Karsten Neuhoff. - 'Lessons Learned from the 2005-2007 Trial Phase of the EU Emission Trading System' by Jan Horst Keppler
Laaring, Mait, 1979-
2003-01-01
Sundvõõrandamise instituudi ajaloolisest arengust, mõistest, omandigarantii olemusest, sundvõõrandamisest ja sotsialiseerimisest (natsionaliseerimisest), sundvõõrandamise õiguspärasuse eeldustest, tagajärgedest, kohtulikust vaidlustamisest
Lasteaia ja lõbumaja vahel : eesti proosa 2008 / Vaapo Vaher
Vaher, Vaapo, 1945-
2009-01-01
Ülevaade 2008. aasta eesti proosast. Pikemalt käsitletakse järgmisi autoreid ja nende teoseid: Mihkel Raud "Musta pori näkku", Olev Remsu "Musketäride muundumised", Rein Põder "Juba olnud", Juhan Nurme "Ligimene", Jaan Tangsoo "Méduse'i parv", Esta Aksli "Tare poole tõttaja", Mari Saat "Lasnamäe lunastaja", Peeter Morgen "Sõnum", Mait Raun "Dr. Mööbi seiklused Inglismaal", Andrei Hvostov "Võõrad lood" ja "Projektijuht Posse", Chaneldior "Kontrolli alt väljas", Vahur Afanasjev "Kosmos", Egon Ilisson "Isased", Jaak Leer "Kaks kabanossi ja Maaja", Kärt Hellerma "Sinine missa", Elo Viiding "Püha Maama", Toomas Raudam "Miks ma ei taha olla kirjanik?", Mart Kivastik "Kurb raamat", Jüri Tuulik "Räim, pisike kena kala", Tarmo Teder "12 jõulujuttu", Dagmar Lamp (koostaja) "Tule, ma jutustan sulle loo", Eia Uus "Kahe näoga jumal", Barthol Lo Mejor "Popdada 2007-2008", Anti Saar "Nemad kaks", Ketlin Priilinn "Liiseli võti" ja "Vaim", Aita Kivi "Lähedal", Marje Ernits "Hoia mu kätt", Kati Murutar "Naisena sündinud : kakskümmend aastat hiljem", Tuule Lind "Pööratud tuul", Siiri Laidla "Lihtne lugu, ehk, Senta suvepuhkus", Kätlin Padesaar "Veel üks paradiis", Aimée Beekman "Proovielu", Lehte Hainslau "Kolmkõla, ehk, 3 kõla", Ira Lember "Ööviiulid", Tamur Kusnets "Hundipäikese aeg : metsiku jahi algus", Kaupo Pähkel "Ehatähe rüütel", Arvo Valton "Ülemiste vanake", Tiit Aleksejev "Palveränd", Ants Eret "Afgaanide vang", Mario Merirand "Afganistani päevik", Leo Kunnas "Gort Ashryn", Rein Raud "Vend", Peeter Sauter "Beibi bluu", Marion Andra "Pimend", Kristjan Sander "13 talvist hetke", Helga Nõu "Peaaegu geenius, ehk, Schrödingeri kassi otsimas", Tiit Sepa "Eefa hüüdnimega Siug", Kaarel ja Klaara Kivi "Varandus seinal", Merike Jürjo "Mälestusteta maja", Rein Vahisalu "Viies kabinet", Aarne Biin "Mees otsib naist", Erik Tohvri "Ümberasujad" ja "Sulasest sai peremees", Arnold Laugus "Elav maa", Jüri v. Grauberg "Selguse poole", J
Lasteaia ja lõbumaja vahel : Eesti proosa 2008 / Vaapo Vaher
Vaher, Vaapo, 1945-
2012-01-01
Ülevaade 2008. aasta eesti proosast. Pikemalt käsitletakse järgmisi autoreid ja nende teoseid: Mihkel Raud "Musta pori näkku", Olev Remsu "Musketäride muundumised", Rein Põder "Juba olnud", Juhan Nurme "Ligimene", Jaan Tangsoo "Méduse'i parv", Esta Aksli "Tare poole tõttaja", Mari Saat "Lasnamäe lunastaja", Peeter Morgen "Sõnum", Mait Raun "Dr. Mööbi seiklused Inglismaal", Andrei Hvostov "Võõrad lood" ja "Projektijuht Posse", Chaneldior "Kontrolli alt väljas", Vahur Afanasjev "Kosmos", Egon Ilisson "Isased", Jaak Leer "Kaks kabanossi ja Maaja", Kärt Hellerma "Sinine missa", Elo Viiding "Püha Maama", Toomas Raudam "Miks ma ei taha olla kirjanik?", Mart Kivastik "Kurb raamat", Jüri Tuulik "Räim, pisike kena kala", Tarmo Teder "12 jõulujuttu", Dagmar Lamp (koostaja) "Tule, ma jutustan sulle loo", Eia Uus "Kahe näoga jumal", Barthol Lo Mejor "Popdada 2007-2008", Anti Saar "Nemad kaks", Ketlin Priilinn "Liiseli võti" ja "Vaim", Aita Kivi "Lähedal", Marje Ernits "Hoia mu kätt", Kati Murutar "Naisena sündinud : kakskümmend aastat hiljem", Tuule Lind "Pööratud tuul", Siiri Laidla "Lihtne lugu, ehk, Senta suvepuhkus", Kätlin Padesaar "Veel üks paradiis", Aimée Beekman "Proovielu", Lehte Hainslau "Kolmkõla, ehk, 3 kõla", Ira Lember "Ööviiulid", Tamur Kusnets "Hundipäikese aeg : metsiku jahi algus", Kaupo Pähkel "Ehatähe rüütel", Arvo Valton "Ülemiste vanake", Tiit Aleksejev "Palveränd", Ants Eret "Afgaanide vang", Mario Merirand "Afganistani päevik", Leo Kunnas "Gort Ashryn", Rein Raud "Vend", Peeter Sauter "Beibi bluu", Marion Andra "Pimend", Kristjan Sander "13 talvist hetke", Helga Nõu "Peaaegu geenius, ehk, Schrödingeri kassi otsimas", Tiit Sepa "Eefa hüüdnimega Siug", Kaarel ja Klaara Kivi "Varandus seinal", Merike Jürjo "Mälestusteta maja", Rein Vahisalu "Viies kabinet", Aarne Biin "Mees otsib naist", Erik Tohvri "Ümberasujad" ja "Sulasest sai peremees", Arnold Laugus "Elav maa", Jüri v. Grauberg "Selguse poole", J
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A.W. Liberatori Filho
1999-07-01
Full Text Available OBJETIVO. No presente estudo propusemo-nos a avaliar, por meio da microscopia de luz, os aspectos morfológicos e morfométricos dos cardiomiócitos do ventrículo esquerdo de ratas albinas durante a prenhez. MÉTODOS. Acasalamos doze ratas virgens que foram dividas ao acaso em quatro grupos, de acordo com a idade gestacional. Os animais correspondentes a cada grupo foram sacrificados ao 1o(G-A, 7o(G-B, 14o(G-C e 21o(G-D dias de prenhez, sendo coletados fragmentos do terço médio do ventrículo esquerdo, os quais após processamento apropriado, permitiram observação adequada à microscopia de luz. A cariometria foi realizada mensurando-se os diâmetros maiores e menores dos cardiomiócitos com o auxílio de um tambor rotativo modelo K 8 X adaptado a um microscópio de luz. RESULTADOS. O estudo em nível da microscopia de luz praticamente não mostrou alterações com o decorrer da prenhez. No entanto, a morfometria revelou que os volumes dos cardiomiócitos estão aumentados no 14o dia da prenhez, mostrando-se estatisticamente significante quando comparado aos demais grupos estudados. Assim, nossos resultados demonstraram haver hipertrofia ventricular esquerda durante a gestação. CONCLUSÃO. Durante a gestação há um processo dinâmico reversível de remodelação ventricular em conseqüência das alterações adaptativas gravídicas.PURPOSE. In the present study we evaluated, by light microscopy, and throughout morphometry, whether hypertrophy of cardiac striated muscular fibers of left ventricular occur in albino rat, during pregnancy. METHODS. After maiting, 12 nuliparous rats were divided into four groups with three animals for each group. The female rats corresponding to each group were killed at 1st, 7th, 14th and 21st days of pregnancy. RESULTS. Observation, on light microscopy (H.E had at one view, did not display any alterations during pregnancy. However, the morphometry revealed that nuclei of cardiomyocytes are augmented in
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González-Pacheco H
2014-10-01
Full Text Available Héctor González-Pacheco,1 Jesús Vargas-Barrón,2 Maite Vallejo,2 Yigal Piña-Reyna,3 Alfredo Altamirano-Castillo,1 Pedro Sánchez-Tapia,1 Carlos Martínez-Sánchez1 1Coronary Care Unit, National Institute of Cardiology in Mexico City, Mexico City, Mexico; 2Department of Clinical Research, National Institute of Cardiology in Mexico City, Mexico City, Mexico; 3Catheterization Laboratory, National Institute of Cardiology in Mexico City, Mexico City, Mexico Background: Among patients with coronary artery disease (CAD, 80%–90% present at least one conventional risk factor. On the other hand, lipid profile modification after a cardiovascular event related to acute coronary syndrome (ACS has been recognized. The prevalence of conventional risk factors and the lipid profile at the time of admission in patients with ACS and significant CAD (stenosis ≥50% determined through coronary angiography is not well described. Methods: We studied 3,447 patients with a diagnosis of ACS and significant CAD with stenosis ≥50%, as shown on angiography. We recorded the presence of conventional risk factors, including smoking, hypertension, dyslipidemia, and diabetes. In addition, we analyzed the lipid profiles within the first 24 hours of admission. We analyzed the studied population and compared findings according to sex.Results: Most patients (81.7% were male. ST-elevation myocardial infarction was present in 51.3% of patients, and non-ST-elevation acute coronary syndrome was present in 48.7%. The most frequent risk factor was smoking, which was present in 68% of patients, followed by hypertension (57.8%, dyslipidemia (47.5%, and diabetes (37.7%. In women, the most frequent risk factors were hypertension, diabetes, and dyslipidemia, whereas in men, smoking was the most frequent. We identified at least one risk factor in 95.7% of all patients, two or three risk factors in 62%, and four risk factors in 8.6% of patients. The lipid profile analysis revealed that
Energy in India's Future: Insights
International Nuclear Information System (INIS)
Lesourne, J.; Ramsay, W.C.; Jaureguy-Naudin, Maite; Boillot, Jean-Joseph; Autheman, Nicolas; Ruet, Joel; Siddiqui, Zakaria; Zaleski, C. Pierre; Cruciani, Michel
2009-01-01
In the decades following India's independence from British rule in 1947, the West's image of India was summarized in three simple cliches: the world's largest democracy, an impoverished continent, and economic growth hampered by a fussy bureaucracy and the caste system, all in a context of a particular religion. These cliches are perhaps one of the reasons that the success of India's green revolution was recognized so late, a revolution that allowed the country to develop its agricultural sector and to feed its population. Since the 1990's, the easing of planning constraints have liberated the Indian economy and allowed it to embark on a more significant path of growth. New cliches have begun to replace the old: India will become a second China and, lagging by 10 to 20 years, will follow the same trajectory, with its development marked more by services and the use of renewable energy. However, these trends will not prevent primary energy demand from exploding. On the contrary, India faces difficult choices on how it increases clean, secure, affordable energy to all its citizens. Many of the choices are the same as found elsewhere, but on a scale matched only by China. The IFRI European Governance and Geopolitics of Energy Project intends this study to deepen public understanding of the magnitude of India's challenges. Various aspects of the serious energy problems are studied throughout this monograph. The authors have written freely on these matters without attempting to reconcile their different viewpoints. The first chapter, by Maite Jaureguy-Naudin and Jacques Lesourne, presents an overview of India's present and future energy system. The authors follow a prudent but realistic view of India's future. The second chapter, by Jean-Joseph Boillot, a French expert on India who has published several books and articles on this subject, and Nicolas Autheman, research fellow, describes in greater detail the specifics of India's economy and the actors who are now present
Energy in India's Future: Insights
Energy Technology Data Exchange (ETDEWEB)
Lesourne, J.; Ramsay, W.C.; Jaureguy-Naudin, Maite; Boillot, Jean-Joseph; Autheman, Nicolas; Ruet, Joel; Siddiqui, Zakaria; Zaleski, C. Pierre; Cruciani, Michel
2009-07-01
In the decades following India's independence from British rule in 1947, the West's image of India was summarized in three simple cliches: the world's largest democracy, an impoverished continent, and economic growth hampered by a fussy bureaucracy and the caste system, all in a context of a particular religion. These cliches are perhaps one of the reasons that the success of India's green revolution was recognized so late, a revolution that allowed the country to develop its agricultural sector and to feed its population. Since the 1990's, the easing of planning constraints have liberated the Indian economy and allowed it to embark on a more significant path of growth. New cliches have begun to replace the old: India will become a second China and, lagging by 10 to 20 years, will follow the same trajectory, with its development marked more by services and the use of renewable energy. However, these trends will not prevent primary energy demand from exploding. On the contrary, India faces difficult choices on how it increases clean, secure, affordable energy to all its citizens. Many of the choices are the same as found elsewhere, but on a scale matched only by China. The IFRI European Governance and Geopolitics of Energy Project intends this study to deepen public understanding of the magnitude of India's challenges. Various aspects of the serious energy problems are studied throughout this monograph. The authors have written freely on these matters without attempting to reconcile their different viewpoints. The first chapter, by Maite Jaureguy-Naudin and Jacques Lesourne, presents an overview of India's present and future energy system. The authors follow a prudent but realistic view of India's future. The second chapter, by Jean-Joseph Boillot, a French expert on India who has published several books and articles on this subject, and Nicolas Autheman, research fellow, describes in greater detail the specifics of India
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Aare Pilv
2013-06-01
Full Text Available The paper gives an overview of a network of authors who have been active since the end of the 20th century, mainly (but not only in Tartu. They can be characterized as having an experimental attitude and maintaining distance from the literary mainstream, but at the same time they do not try to be consciously polemical or novatory, because partly they repeat the techniques of the 20th century avant-garde and, what is maybe more important, they sidestep the dialectics of innovating or altering the literary canon. The network is not strictly organized; it is rather a rhizome that has some denser nodes (literary journals and mailing lists. There have been different attempts to name the phenomenon: Tartu avant-garde, microcosmic literature, cognitive realism, Y-literature, "eksp" and so on. I have chosen "paranoiac-critique" as the term that best captures the common characteristics of these authors and their artistic practices (some of the authors are active not only as text writers, but also as conceptual artists.The paper then gives a list, with commentary, of the most important groups and individuals of that movement. In the role of "predecessors" are the group 14NÜ (Paavo Matsin, Mait Laas, Marianne Ravi et al., which also experimented with the format of the book, and a company in Tartu that developed a specific actionist stylistics called "mugiv" (Marko Kompus, Mehis Heinsaar, Martiini, Kaspar et al.. The sovereign figure in the experimental network is Valdur Mikita, who has also academically researched the problems of creativity; he is also a theoretician and metapoet. An important institution for the network has been the literary journal Vihik (initiator Berk Vaher; the later editor of the journal Jaak Tomberg has also participated in activities of the Tartu Theatre Laboratory (managed by Andreas W, which has experimented with "technological theatre". In the middle of the first decade of the 21st century the network has gathered around the
PREFACE: Loops 11: Non-Perturbative / Background Independent Quantum Gravity
Mena Marugán, Guillermo A.; Barbero G, J. Fernando; Garay, Luis J.; Villaseñor, Eduardo J. S.; Olmedo, Javier
2012-05-01
only was it a showroom for the research currently being carried out by many groups throughout the world, but there was also a permanent look towards the future. During these days, the CSIC Campus witnessed many scientific conversations triggered by the interaction amongst the people and groups that participated in LOOPS'11 Madrid and which, in many cases, will crystallise into new results and advances in the field. The conference would not have been possible without the generous help of a number of national and international institutions. The organizers would like to acknowledge the financial support provided by the Spanish Ministry of Science and Innovation (Ministerio de Ciencia e Innovación), the Spanish Research Council, CSIC (Consejo Superior de Investigaciones Cientĺficas), The BBVA Foundation (Fundación BBVA), The CONSOLIDER-CPAN project, the Spanish Society for Gravitation and Relativity (SEGRE), The Universidad Carlos III of Madrid (UC3M), and the European Science Foundation (ESF). The ESF, through the Quantum Gravity and Quantum Geometry network, provided full support for a number of young participants that have contributed to these proceedings: Dario Benedetti (Albert Einstein Institute, Potsdam, Germany), Norbert Bodendorfer (Institute for Theoretical Physics III, FAU Erlangen Nürnberg, Germany), Mariam Bouhmadi López (CENTRA, Centro Multidisciplinar de Astrofĺsica, Lisbon), Timothy Budd (Institute for Theoretical Physics, Utrecht University, The Netherlands), Miguel Campiglia (Institute for Gravitation and the Cosmos, Penn State University, USA), Gianluca Delfino (School of Mathematical Sciences, University of Nottingham, UK), Maite Dupuis (Institute for Theoretical Physics III, FAU Erlangen Nürnberg, Germany), Michał Dziendzikowski (Institute of Theoretical Physics, Warsaw University, Poland), Muxin Han (Centre de Physique Théorique de Luminy, Marseille, France), Philipp Höhn (Institute for Theoretical Physics, Utrecht University, The
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Ave Mattheus
2012-04-01
Full Text Available In this article I discuss autobiographical texts which focus on children and childhood in late 19th century Estonia. Childhood memories as well as other autobiographical material became popular in Estonia in the 1920s-1930s, when most of the studied works--the memoirs by Anna Haava, Mait Metsanurk, Jaan Lattik, Jaan Vahtra, Friedebert Tuglas, August Kitzberg and Marta Sillaots--were written. Some texts come from the 19th century (e.g. Lilli Suburg’s autobiographical works or early 20th century (e.g. manuscripts by Hans Leoke, and Johannes Kõrv. Childhood as described in these autobiographical texts covers a period of circa 1850-1900, and the majority of the authors come from the families of South-Estonian peasants or manorial servants. In addition to being written in Estonian and having the same theme, they were all also written by authors of fiction for children or by people who had close contact with children, such as schoolteachers. The article offers a novel approach in the Estonian context by presenting a typology of childhood stories and looking at childhood recollections as an important part of childhood studies. The researchers of childhood investigate how society understands and values children and childhood, what children’s everyday life is like, what possibilities there are for development and if there exists a specific children’s culture in society (such as clothing, food, language, leisure activities, or independent creative work. Childhood studies as a separate discipline does not exist in Estonia, although some important works have been published by educational scholars and art historians. The autobiographical texts under discussion show that in the late 19th century, the majority of Estonian children lived in the countryside in patriarchal families, and childhood was short because children had to help their parents with farmwork quite early, at the age of six. The boundary of childhood was around the age of 10-11, when