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Sample records for treatments equally effective

  1. Steroid Treatments Equally Effective Against Sudden Deafness

    Science.gov (United States)

    ... NIGMS NIMH NIMHD NINDS NINR NLM CC CIT CSR FIC NCATS NCCIH OD About NIH Who We ... with sudden deafness should discuss the risks and benefits of both treatments with their doctor.” Related Links ...

  2. Equal treatment of shareholders

    Directory of Open Access Journals (Sweden)

    Arsić Zoran

    2014-01-01

    Full Text Available Equal treatment of shareholders is regulated in Art.269 of Company Act (2011 of Republic of Serbia. Equal treatment of shareholders means that all shareholders are to be treated equally under same circumstances. Obligation to treat all shareholders equally rests on all company bodies, predominantly general meeting. The standard whether an action violates the principle of equal treatment of all shareholders regarding the main rights of shareholders (such as voting right etc. is the nominal value of shares, or the equal treatment per person regarding ancillary rights (such as right to speak in shareholders' meeting etc.. Any action deviating from this standard is unlawful if the unequal treatment is not justified on the facts. If the principle of equal treatment is violated by general meeting resolution, such resolution may be annulled by the court.

  3. Minority Adolescents in Ethnically Diverse Schools: Perceptions of Equal Treatment Buffer Threat Effects

    Science.gov (United States)

    Baysu, Gülseli; Celeste, Laura; Brown, Rupert; Verschueren, Karine; Phalet, Karen

    2016-01-01

    Can perceptions of equal treatment buffer the negative effects of threat on the school success of minority students? Focusing on minority adolescents from Turkish and Moroccan heritage in Belgium (M[subscript age] = 14.5; N = 735 in 47 ethnically diverse schools), multilevel mediated moderation analyses showed: (a) perceived discrimination at…

  4. Equal Work Require Equal Salary” – Part of the Principle of Equality Treatment between Men and Women

    Directory of Open Access Journals (Sweden)

    Carla Carmina Spiridon

    2009-12-01

    Full Text Available Enlarging the provisions of Universal Declaration of Human Rights, The Convention no. 111 from 1958 regarding discrimination in the field of employing manpower and practicing profession, , has pointed out the effect of discrimination: to suppress or to prejudice the equal opportunities or treatment in the field of employing manpower and practicing profession.

  5. realising equality in access to hiv treatment for vulnerable

    African Journals Online (AJOL)

    UOVS

    been recognised that equality is tantamount to non-discrimination. .... HIV/AIDS), sexual orientation, and civil, political, social or other status which has ... ensuring equal HIV treatment for children, sex workers and men who have sex with.

  6. Political Liberalism, Linguistic Diversity and Equal Treatment

    Science.gov (United States)

    Bonotti, Matteo

    2017-01-01

    This article explores the implications of John Rawls' political liberalism for linguistic diversity and language policy, by focusing on the following question: what kind(s) of equality between speakers of different languages and with different linguistic identities should the state guarantee under political liberalism? The article makes three…

  7. Smokers with ST-segment elevation myocardial infarction and short time to treatment have equal effects of PCI and fibrinolysis

    DEFF Research Database (Denmark)

    Rasmussen, Thomas; Kelbæk, Henning Skov; Madsen, Jan Kyst

    2012-01-01

    The purpose of this study was to examine the effect of primary percutaneous coronary intervention (PCI) compared to fibrinolysis in smokers and non-smokers with ST-segment elevation myocardial infarction (STEMI). Smokers seem to have less atherosclerosis but are more prone to thrombotic disease....... Compared to non-smokers, they have higher rates of early, complete reperfusion when treated with fibrinolysis for MI....

  8. Realising Equality in Access to HIV Treatment for Vulnerable and ...

    African Journals Online (AJOL)

    This article examines the relevance of the concept of equality in improving access to HIV treatment for vulnerable and marginalised groups in Africa. The article argues that though modest achievements have been made in expanding access to HIV treatment for those in need in Africa, this expansion has concentrated on the ...

  9. Multiculturalism and Equal Treatment: Scope and Limits of the ...

    African Journals Online (AJOL)

    In this paper, I examine the scope and limits of Brian Barry's uniform treatment approach to cultural differences through a critical assessment of its two main arguments. The first maintains that under a regime of institutions serving legitimate public purposes, equal opportunity is an objective state of affairs, and religious or ...

  10. The ESTRO European assurance programme for radiation treatments (EQUAL Network)

    International Nuclear Information System (INIS)

    Ferreira, I.H.; Dutreix, A.; Bridier, A.; Svensson, H.

    2002-01-01

    The European Society for Therapeutic Radiology and Oncology (ESTRO) Quality Assurance network for radiotherapy (EQUAL) has been set up in 1998 for European countries. This TLD postal dose assurance service addresses to photon and electron beam checks in reference and non-reference conditions and is successful with more than 440 radiotherapy centres and 1,656 beams checked. Dosimetric problems in the beam calibration, errors in beam data used as input to the treatment planning system (TPS), or uncertainties in the algorithms used in the TPS can be detected in the EQUAL audit. The EQUAL reference dosimetry is linked to the IAEA dosimetry laboratory and to the Radiological Physics Center (RPC) dosimetry laboratory by periodic intercomparisons. The absorbed doses to water in photon and electron beams, measured with the ionization chambers, are determined following the procedure described in the new IAEA TRS-398 International Code of Practice for dosimetry based on standards of absorbed dose to water. The participating centres are instructed to irradiate the TLD (LiF) capsules to a dose of 2 Gy according to the calculations given by the Treatment Planning System used in clinical routine. For photon beams, the EQUAL checks four dosimetric parameters: the reference beam output, the percentage depth doses, the beam output variation for open and wedged fields and the wedge transmission factor. In electron TLD audits, beam outputs are checked for 4 different field sizes. EQUAL has checked 440 radiotherapy centres corresponding to 1,656 beams (1009 photon beams and 574 electrons beams and 73 photon beams shaped by multileaf collimators). The results from measurements at the reference point are very good both for photon and electron beams. For photons, the rates of deviation (vertical bar d vertical bar D measured- D stated ) x 100 / D stated ) larger than 5% which have been observed are respectively of 2.6% for the beam output variation and 3.5% for the wedge transmission

  11. Analysis of covariance with pre-treatment measurements in randomized trials: comparison of equal and unequal slopes.

    Science.gov (United States)

    Funatogawa, Ikuko; Funatogawa, Takashi

    2011-09-01

    In randomized trials, an analysis of covariance (ANCOVA) is often used to analyze post-treatment measurements with pre-treatment measurements as a covariate to compare two treatment groups. Random allocation guarantees only equal variances of pre-treatment measurements. We hence consider data with unequal covariances and variances of post-treatment measurements without assuming normality. Recently, we showed that the actual type I error rate of the usual ANCOVA assuming equal slopes and equal residual variances is asymptotically at a nominal level under equal sample sizes, and that of the ANCOVA with unequal variances is asymptotically at a nominal level, even under unequal sample sizes. In this paper, we investigated the asymptotic properties of the ANCOVA with unequal slopes for such data. The estimators of the treatment effect at the observed mean are identical between equal and unequal variance assumptions, and these are asymptotically normal estimators for the treatment effect at the true mean. However, the variances of these estimators based on standard formulas are biased, and the actual type I error rates are not at a nominal level, irrespective of variance assumptions. In equal sample sizes, the efficiency of the usual ANCOVA assuming equal slopes and equal variances is asymptotically the same as those of the ANCOVA with unequal slopes and higher than that of the ANCOVA with equal slopes and unequal variances. Therefore, the use of the usual ANCOVA is appropriate in equal sample sizes. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Test Equality between Three Treatments under an Incomplete Block Crossover Design.

    Science.gov (United States)

    Lui, Kung-Jong

    2015-01-01

    Under a random effects linear additive risk model, we compare two experimental treatments with a placebo in continuous data under an incomplete block crossover trial. We develop three test procedures for simultaneously testing equality between two experimental treatments and a placebo, as well as interval estimators for the mean difference between treatments. We apply Monte Carlo simulations to evaluate the performance of these test procedures and interval estimators in a variety of situations. We note that the bivariate test procedure accounting for the dependence structure based on the F-test is preferable to the other two procedures when there is only one of the two experimental treatments has a non-zero effect vs. the placebo. We note further that when the effects of the two experimental treatments vs. a placebo are in the same relative directions and are approximately of equal magnitude, the summary test procedure based on a simple average of two weighted-least-squares (WLS) estimators can outperform the other two procedures with respect to power. When one of the two experimental treatments has a relatively large effect vs. the placebo, the univariate test procedure with using Bonferroni's equality can be still of use. Finally, we use the data about the forced expiratory volume in 1 s (FEV1) readings taken from a double-blind crossover trial comparing two different doses of formoterol with a placebo to illustrate the use of test procedures and interval estimators proposed here.

  13. Custom LSI plus hybrid equals cost effectiveness

    Science.gov (United States)

    Friedman, S. N.

    The possibility to combine various technologies, such as Bi-Polar linear and CMOS/Digital makes it feasible to create systems with a tailored performance not available on a single monolithic circuit. The custom LSI 'BLOCK', especially if it is universal in nature, is proving to be a cost effective way for the developer to improve his product. The custom LSI represents a low price part in contrast to the discrete components it will replace. In addition, the hybrid assembly can realize a savings in labor as a result of the reduced parts handling and associated wire bonds. The possibility of the use of automated system manufacturing techniques leads to greater reliability as the human factor is partly eliminated. Attention is given to reliability predictions, cost considerations, and a product comparison study.

  14. EQUAL TREATMENT AND NON DISCRIMINATION ON GENDER CRITERIUM IN ROMANIAN LAW

    Directory of Open Access Journals (Sweden)

    TOFAN Mihaela

    2012-06-01

    Full Text Available There have been important changes in Romanian legal framework in the past two decades. Concepts as liberty, equality and equity evolved from declarative level to effective values applied into reality. Romanian Constitution, adopted in 1991 and considerably reviewed in 2003, started the process of adapting the Romanian legal framework to the European law. Fundamental principles, such as liberty, equal treatment and equality between all individuals have been ruled and are in force, as they are included in the constitutional texts. In order to confer stronger guaranties for respecting these principles, there have been adopted laws, ordinances and regulations. Although the separation of the power is ruled on constitutional level, the Romanian govern has the power to adopt ordinances, when the parliament is not able to act. This power is not used properly, the process of ruling through ordinances being the prior method and not the exception, as it should be. So, the equal treatment and the non-discrimination principles are insured by ordinance, many of the aspects being criticized. The constant, systematic and concentrated promotion of the equal opportunity principle for men and women, as it is known today, represents a relatively new worry for the international community, even though legal aspects about equality between men and women have been evoked ever since 1948 in the Universal Declaration of Human Rights. In the European Union, the preoccupation for the promotion of the equal opportunity and treatment for men and women was officially recognized as a necessity starting with the European Treaty from Maastricht (1993, and subsidiary through the adopted Directives for this purpose and not least through the jurisprudence of Luxembourg’s Court of Law. On institutional level, there have been founded some private and also public bodies to carry out the mission of protecting the equal treatment and non-discrimination principles. An important role is

  15. Equal but different: Effects of equality/inclusion and cultural pluralism on intergroup outcomes in multiethnic classrooms.

    Science.gov (United States)

    Schwarzenthal, Miriam; Schachner, Maja K; van de Vijver, Fons J R; Juang, Linda P

    2018-04-01

    Integrating research on intergroup contact and intercultural relations, we investigated effects of 2 types of cultural diversity norms (equality/inclusion and cultural pluralism) on outgroup orientation and perceived discrimination among students of immigrant and nonimmigrant background. Our sample comprised 1,975 6th graders (M age = 11.53, SD age = 0.69, 47% female) in Germany, of whom 1,213 (61%) were of immigrant background, defined as having at least 1 parent born in a different country. A total of 83 countries of origin were represented. We applied a multilevel framework to assess the impact of individual-level and class-level predictors on intergroup outcomes, controlling for the classroom ethnic composition, school track, and individual-level covariates. Immigrant background was treated as a moderator. The 2 types of cultural diversity norms were generally associated with more positive intergroup outcomes. Some of the associations differed in strength between students of immigrant and nonimmigrant background. There were stronger associations of equality/inclusion with higher outgroup orientation among students of nonimmigrant background and with lower perceived discrimination among students of immigrant background. Ethnic composition, as well as the classroom-aggregated diversity norms (diversity climate) showed weaker relations with the outcome variables. Equality/inclusion norms and cultural pluralism norms can make complementary contributions to positive relations between students of immigrant and nonimmigrant background. Equality/inclusion norms foster positive contact and equal treatment, while cultural pluralism norms emphasize that it is also important to value diversity.¹ (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  16. [Are all diuretics equal for the treatment of hypertensive patients?].

    Science.gov (United States)

    Waeber, B; Feihl, F

    2012-09-12

    Thiazide (hydrochlorothiazide,...) and thiazide-like (chlortalidone, indapamide,...) diuretics are widely used to treat hypertensive patients. There is growing evidence that these diuretics are not interchangeable and that it might be preferable to choose a thiazide-like diuretic whenever the use of a diuretic is considered. This is in order to prevent optimally the development of cardiovascular complications and the occurrence of metabolic side effects, in particular diabetes.

  17. Treatment Effects

    DEFF Research Database (Denmark)

    Heckman, James J.; Lopes, Hedibert F.; Piatek, Rémi

    2014-01-01

    This paper contributes to the emerging Bayesian literature on treatment effects. It derives treatment parameters in the framework of a potential outcomes model with a treatment choice equation, where the correlation between the unobservable components of the model is driven by a low-dimensional v......This paper contributes to the emerging Bayesian literature on treatment effects. It derives treatment parameters in the framework of a potential outcomes model with a treatment choice equation, where the correlation between the unobservable components of the model is driven by a low...... to observe the same person in both the treated and untreated states, but it also turns out to be straightforward to implement. Formulae are provided to compute mean treatment effects as well as their distributional versions. A Monte Carlo simulation study is carried out to illustrate how the methodology can...

  18. Observations and actions to ensure equal treatment of all candidates by the European Research Council

    Science.gov (United States)

    Rydin, Claudia Alves de Jesus; Farina Busto, Luis; El Mjiyad, Nadia; Kota, Jhansi; Thelen, Lionel

    2017-04-01

    The European Research Council (ERC), Europe's premiere funding agency for frontier research, views equality of opportunities as an important challenge. The ERC monitors closely gender figures on every call and has taken actions to tackle imbalances and potential unconscious biases. The ERC talk is focused on efforts made to understand and ensure equal treatment of all candidates, with particular focus on gender balance and with specific attention to geosciences. Data and statistics collected in running highly competitive and internationally recognised funding schemes are presented. Recent initiatives to tackle geographical imbalances will also be presented.

  19. The Effect of Gender Equality on International Soccer Performance

    DEFF Research Database (Denmark)

    Bredtmann, Julia; Crede, Carsten J.; Otten, Sebastian

    2014-01-01

    In this paper, we propose a new estimation strategy that uses the variation in success between the male and the female national soccer team within a country to identify the causal impact of gender equality on women’s soccer performance. In particular, we analyze whether within-country variations...... in labor force participation rates and life expectancies between the genders, which serve as measures for the country’s gender equality, are able to explain diff erences in the international success of male and female national soccer teams. Our results reveal that diff erences in male and female labor...... force participation rates and life expectancies are able to explain the international soccer performance of female teams, but not that of male teams, suggesting that gender equality is an important driver of female sport success....

  20. Pre-treatment with antibiotics and Escherichia coli to equalize the gut microbiota in conventional mice.

    Science.gov (United States)

    Linninge, Caroline; Ahrné, Siv; Molin, Göran

    2015-01-01

    The composition of the gut microbiota can vary widely between individual mice of the same batch and thereby affect the resulting outcome in experimental studies. Therefore, an efficient method is needed to equalize the gut microbiota prior to the start of critical experiments. In order to minimize variations in gut microbiota between animals and provide the animals with a Gram-negative flora exposing lipopolysaccharides in the cell-walls, C57BL/6 mice were given a mixture of ampicillin, metronidazole and clindamycin in the drinking water for 3 days and then Escherichia coli for two additional days. Treatment with antibiotics alone or with antibiotics in combination with E. coli was well tolerated by all animals. Body weight and liver weight were not affected, although higher hepatic fat content was found in treated animals (p antibiotics and antibiotics in combination with E. coli (p < 0.01), without affecting the total amount of bacteria. Cloned and sequenced 16S rRNA genes showed high presence of Enterobacteriaceae and Porphymonadaceae in the treated animals. Analysis with Principal Component Analysis gave a clear separation of the composition in microbiota between different treatment groups. The described treatment efficiently equalized the gut microbiota and provided the animals with a strong abundance of Enterobacteriaceae without changing the total load of bacteria. This is a straightforward, lenient and efficient method of pre-treatment to equalize the gut microbiota of mice as a starting procedure of animal studies.

  1. TOIB Study. Are topical or oral ibuprofen equally effective for the treatment of chronic knee pain presenting in primary care: a randomised controlled trial with patient preference study. [ISRCTN79353052

    Directory of Open Access Journals (Sweden)

    Parsons Suzanne

    2005-11-01

    Full Text Available Abstract Background Many older people have chronic knee pain. Both topical and oral non- steroidal anti-inflammatory drugs (NSAIDs are commonly used to treat this. Oral NSAIDS are effective, at least in the short term, but can have severe adverse effects. Topical NSAIDs also appear to be effective, at least in the short term. One might expect topical NSAIDs both to be less effective and to have fewer adverse effects than oral NSAIDs. If topical NSAIDs have fewer adverse effects this may outweigh both the reduction in effectiveness and the higher cost of topical compared to oral treatment. Patient preferences may influence the comparative effectiveness of drugs delivered via different routes. Methods TOIB is a randomised trial comparing topical and oral ibuprofen, with a parallel patient preference study. We are recruiting people aged 50 or over with chronic knee pain, from 27 MRC General Practice Research Framework practices across the UK. We are seeking to recruit 283 participants to the RCT and 379 to the PPS. Participants will be followed up for up to two years (with the majority reaching one year. Outcomes will be assessed by postal questionnaire, nurse examination, laboratory tests and medical record searches at one and two years or the end of the study. Discussion This study will provide new evidence on the overall costs and benefits of treating chronic knee pain with either oral or topical ibuprofen. The use of a patient preference design is unusual, but will allow us to explore how preference influences response to a medication. In addition, it will provide more information on adverse events. This study will provide evidence to inform primary care practitioners, and possibly influence practice.

  2. Older and Younger Workers: The Equalling Effects of Health

    Science.gov (United States)

    Beck, Vanessa; Quinn, Martin

    2012-01-01

    Purpose: The purpose of this paper is to consider the statistical evidence on the effects that ill health has on labour market participation and opportunities for younger and older workers in the East Midlands (UK). Design/methodology/approach: A statistical analysis of Labour Force Survey data was undertaken to demonstrate that health issues…

  3. Equality judgments cannot distinguish between attention effects on appearance and criterion: a reply to Schneider (2011).

    Science.gov (United States)

    Anton-Erxleben, Katharina; Abrams, Jared; Carrasco, Marisa

    2011-01-01

    Whether attention modulates the appearance of stimulus features is debated. Whereas many previous studies using a comparative judgment have found evidence for such an effect, two recent studies using an equality judgment have not. Critically, these studies have relied on the assumption that the equality paradigm yields bias-free PSE estimates and is as sensitive as the comparative judgment, without testing these assumptions. Anton-Erxleben, Abrams, and Carrasco (2010) compared comparative judgments and equality judgments with and without the manipulation of attention. They demonstrated that the equality paradigm is less sensitive than the comparative judgment and also bias-prone. Furthermore, they reported an effect of attention on the PSE using both paradigms. Schneider (2011) questions the validity of the latter finding, stating that the data in the equality experiment are corrupted because of skew in the response distributions. Notably, this argument supports the original conclusion by Anton-Erxleben et al.: that the equality paradigm is bias-prone. Additionally, the necessary analyses to show that the attention effect observed in Anton-Erxleben et al. was due to skew in the data were not conducted. Here, we provide these analyses and show that although the equality judgment is bias-prone, the effects we observe are consistent with an increase of apparent contrast by attention.

  4. The effect of centralization of health care services on travel time and its equality.

    Science.gov (United States)

    Kobayashi, Daisuke; Otsubo, Tetsuya; Imanaka, Yuichi

    2015-03-01

    To analyze the regional variations in travel time between patient residences and medical facilities for the treatment of ischemic heart disease and breast cancer, and to simulate the effects of health care services centralization on travel time and equality of access. We used medical insurance claims data for inpatients and outpatients for the two target diseases that had been filed between September 2008 and May 2009 in Kyoto Prefecture, Japan. Using a geographical information system, patient travel times were calculated based on the driving distance between patient residences and hospitals via highways and toll roads. Locations of residences and hospital locations were identified using postal codes. We then conducted a simulation analysis of centralization of health care services to designated regional core hospitals. The simulated changes in potential spatial access to care were examined. Inequalities in access to care were examined using Gini coefficients, which ranged from 0.4109 to 0.4574. Simulations of health care services centralization showed reduced travel time for most patients and overall improvements in equality of access, except in breast cancer outpatients. Our findings may contribute to the decision-making process in policies aimed at improving the potential spatial access to health care services. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  5. Effects of stimulus order on discrimination processes in comparative and equality judgements: data and models.

    Science.gov (United States)

    Dyjas, Oliver; Ulrich, Rolf

    2014-01-01

    In typical discrimination experiments, participants are presented with a constant standard and a variable comparison stimulus and their task is to judge which of these two stimuli is larger (comparative judgement). In these experiments, discrimination sensitivity depends on the temporal order of these stimuli (Type B effect) and is usually higher when the standard precedes rather than follows the comparison. Here, we outline how two models of stimulus discrimination can account for the Type B effect, namely the weighted difference model (or basic Sensation Weighting model) and the Internal Reference Model. For both models, the predicted psychometric functions for comparative judgements as well as for equality judgements, in which participants indicate whether they perceived the two stimuli to be equal or not equal, are derived and it is shown that the models also predict a Type B effect for equality judgements. In the empirical part, the models' predictions are evaluated. To this end, participants performed a duration discrimination task with comparative judgements and with equality judgements. In line with the models' predictions, a Type B effect was observed for both judgement types. In addition, a time-order error, as indicated by shifts of the psychometric functions, and differences in response times were observed only for the equality judgement. Since both models entail distinct additional predictions, it seems worthwhile for future research to unite the two models into one conceptual framework.

  6. Tests of equal effect per fraction in microcolony assays of survival after fractionated irradiations

    International Nuclear Information System (INIS)

    Taylor, J.M.G.

    1985-01-01

    H.D Thames, Jr. and H.R. Withers propose a test of an equal effect per fraction in microcolony assays after fractionated radiation, in which the total effect is measured by counting microcolonies derived from surviving cells in a tissue. The factors considered to influence the cytocidal effect per fraction are incomplete repair, repopulation, and synchrony. The statistics used in the method are criticized and conditions are given under which the test should not be used. An alternative method of testing for an equal effect per fraction is proposed. The pros and cons of each test are discussed and compared using some mouse jejunal crypt cell survival data

  7. From equality to 'equality'

    Directory of Open Access Journals (Sweden)

    Panov Slobodan

    2009-01-01

    Full Text Available Pursuant to lucid statement of a Serbian academician that the ideals of mankind have always been justice, freedom, virtues and that life was less noble, the work analyses whether there is both 'equality', as morosofo exist (stupid wise men, profitable altruists and evil humanists and admirers of freedom of monistic thinking. Is there a dialectics: from equality to 'equality'? At the time of profitable altruists, evil humanists and excellent actors of virtues, it is worthwhile to remember Nietzsche's attitude about the pose of morality: subordination to morality may be slavish, proud, sordid, and resigned. In theological literature it is said that both patriarchate and matriarchate are the same denial of thankful supplemental gifts to a man and a woman. There is no love and sacrifice in government. There is no fortune in slavery, but there is no happiness in mastery either. Can a 'hymn' of individualism, with empty concepts and legal formulations that encourage and sharpen the conflict of family members be an introductory tact of the dictatorship ballade? Is the projection of conflicts into a family and micro-environment a project against emotional solidarity, strength, independence, courage and will for freedom? If we cannot rely upon family are we strong enough to confront totalitarian in democratic?.

  8. Incomplete equalization

    DEFF Research Database (Denmark)

    Holm, Anders; Jæger, Mads Meier; Karlson, Kristian Bernt

    2013-01-01

    improve access to lower-tier higher education for low-SES students. These findings point to an interesting paradox in that tracking has adverse effects at the micro-level but equalizes educational opportunities at the macro-level. We also discuss whether similar mechanisms might exist in other educational...

  9. Equal treatment for new renewable heating and power; Likebehandling av ny fornybar varme og kraft

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-12-20

    If a system of electric certificates is established in Norway, adjustments in the conditions of competition will need to be made for green heating production, assuring that green heating does not lose in the competition with green electricity (el). To ensure that the terms of competition are as equal as possible the most efficient policy instrument is to include heating in a common certificate system for el and heating. If it is not possible to establish a common system of certificates, the best policy instrument will be to ensure equal conditions of competition.

  10. Improving models of democracy: the example of lagged effects of economic development, education, and gender equality.

    Science.gov (United States)

    Balaev, Mikhail

    2014-07-01

    The author examines how time delayed effects of economic development, education, and gender equality influence political democracy. Literature review shows inadequate understanding of lagged effects, which raises methodological and theoretical issues with the current quantitative studies of democracy. Using country-years as a unit of analysis, the author estimates a series of OLS PCSE models for each predictor with a systematic analysis of the distributions of the lagged effects. The second set of multiple OLS PCSE regressions are estimated including all three independent variables. The results show that economic development, education, and gender have three unique trajectories of the time-delayed effects: Economic development has long-term effects, education produces continuous effects regardless of the timing, and gender equality has the most prominent immediate and short term effects. The results call for the reassessment of model specifications and theoretical setups in the quantitative studies of democracy. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. Are there biologic differences between male and female breast cancer explaining inferior outcome of men despite equal stage and treatment?

    International Nuclear Information System (INIS)

    Mueller, A.C.; Gani, C.; Rehm, H.M.E.; Eckert, F.; Bamberg, M.; Weinmann, M.; Hehr, T.

    2012-01-01

    Background: Reasons for inferior outcome of male compared to female breast cancer are still under debate. Therefore, we retrospectively analyzed male breast cancer cases to figure out possible treatment- and gender-related differences. Patients and methods: A total of 40 men (median age 62 years) were curatively treated with mastectomy and postoperative radiotherapy from 1982-2007. They presented predominantly in stages II and IIIb. Postoperative radiotherapy was applied with doses of 1.8-2.5 Gy to a median of 50 Gy including regional lymphatics in 22 patients. Adjuvant systemic treatment consisted of chemotherapy (22.5%) and antihormonal treatment (55%). For reasons of comparison, we estimated outcome of a virtual female matched cohort for no/equal to men/optimal adjuvant treatment with the Adjuvant.Online registered 8.0 algorithm. Results: After a median follow-up of 47 months, the estimated 5-year local control rate was 97%, disease-free and distant metastasis-free survival rates reached 79% and 82%, respectively. With update of survival data by tumor registry, mean overall survival reached 120 months with 5- and 10-year overall survival rates of 66% and 43%, respectively. Predominant prognostic factor was T-stage for overall survival (T1/2 vs. T4: > 80% vs. 30%). The generated virtual matched cohorts of women with equal characteristics reached superior 10-year-overall survival for no/equal to men/optimal adjuvant treatment with 55/59/68%. Conclusion: Compared to historical and virtual matched cohorts of women, male breast cancer patients had inferior outcome despite of equal stage and treatment which indicates that biological differences (of tumor or population) may contribute to worse prognosis. (orig.)

  12. Are there biologic differences between male and female breast cancer explaining inferior outcome of men despite equal stage and treatment?.

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, A.C.; Gani, C.; Rehm, H.M.E.; Eckert, F.; Bamberg, M.; Weinmann, M. [Tuebingen Univ. (Germany). Dept. of Radiooncology; Hehr, T. [Marienhospital Stuttgart (Germany). Dept. of Radiooncology

    2012-09-15

    Background: Reasons for inferior outcome of male compared to female breast cancer are still under debate. Therefore, we retrospectively analyzed male breast cancer cases to figure out possible treatment- and gender-related differences. Patients and methods: A total of 40 men (median age 62 years) were curatively treated with mastectomy and postoperative radiotherapy from 1982-2007. They presented predominantly in stages II and IIIb. Postoperative radiotherapy was applied with doses of 1.8-2.5 Gy to a median of 50 Gy including regional lymphatics in 22 patients. Adjuvant systemic treatment consisted of chemotherapy (22.5%) and antihormonal treatment (55%). For reasons of comparison, we estimated outcome of a virtual female matched cohort for no/equal to men/optimal adjuvant treatment with the Adjuvant.Online {sup registered} 8.0 algorithm. Results: After a median follow-up of 47 months, the estimated 5-year local control rate was 97%, disease-free and distant metastasis-free survival rates reached 79% and 82%, respectively. With update of survival data by tumor registry, mean overall survival reached 120 months with 5- and 10-year overall survival rates of 66% and 43%, respectively. Predominant prognostic factor was T-stage for overall survival (T1/2 vs. T4: > 80% vs. 30%). The generated virtual matched cohorts of women with equal characteristics reached superior 10-year-overall survival for no/equal to men/optimal adjuvant treatment with 55/59/68%. Conclusion: Compared to historical and virtual matched cohorts of women, male breast cancer patients had inferior outcome despite of equal stage and treatment which indicates that biological differences (of tumor or population) may contribute to worse prognosis. (orig.)

  13. School Segregation and Its Effects on Educational Equality and Efficiency in 16 OECD Comprehensive School Systems

    Science.gov (United States)

    Benito, Ricard; Alegre, Miquel Àngel; Gonzàlez-Balletbò, Isaac

    2014-01-01

    Using PISA data for 16 Western OECD countries having comprehensive school systems, we explore the conditions under which the socioeconomic composition of schools affects educational efficiency and equality, to a greater or lesser extent. First, a multilevel analysis is applied to examine and compare the effect of school socioeconomic composition…

  14. Social justice and equal treatment for pregnant women in the workplace

    OpenAIRE

    2012-01-01

    LL.D. This thesis critically evaluates the position of pregnant women (and women who have recently given birth) in the context of South African Labour Law and social security law, from both a comparative and a South African perspective. The fact that women fall pregnant and give birth to children, while men do not, raises issues of theoretical and practical importance in regard to equality issues. Pregnancy has historically been both the cause of and the occasion for the exclusion of many ...

  15. Therapeutic effect of turquoise versus blue light with equal irradiance in preterm infants with jaundice

    DEFF Research Database (Denmark)

    Ebbesen, Finn; Madsen, Poul; Støvring, Søren

    2007-01-01

    AIM: To compare the efficiency of turquoise light with that of TL52 blue in treatment of preterm infants with jaundice at the same level of body irradiance. METHODS: Infants with gestational age 28-37 weeks and non-haemolytic hyperbilirubinemia were treated for 24 h with either turquoise light (O......,Z-bilirubin and lumirubin, in infants under turquoise light. This suggests, given equal irradiances, that light in the turquoise spectral range is preferable to the TL52 blue in treatment of newborn jaundiced infants....

  16. Scientific Evidence in the Study and Treatment of Addictive Behaviours in Psychosocial Intervention. Journal on Equality and Quality of Life

    Directory of Open Access Journals (Sweden)

    Itziar Iruarrizaga Díez

    2010-02-01

    Full Text Available In Spain, the importance and relevance of substance dependence and other addictive behaviours has generated great interest among the scientific community. Since its creation in 1992, Psychosocial Intervention. Journal on Equality and Quality of Life has transmitted the needs and training demands of psychologists, paying special attention to those aspects related to prevention, health outcomes and psychosocial factors involved in the onset and maintenance of drug addiction, psychosocial intervention and the treatment of addictive behaviours. As an introduction to this report on the Scientific evidence in the study and treatment of addictive behaviours, all topics covered by this journal throughout the years will be addressed.

  17. Treatment of corneal astigmatism with the new small-incision lenticule extraction (SMILE) laser technique: Is treatment of high degree astigmatism equally accurate, stable and safe as treatment of low degree astigmatism?

    DEFF Research Database (Denmark)

    Hansen, Rasmus Søgaard; Lyhne, Niels; Grauslund, Jakob

    .6%) treated for low astigmatism and four eyes (3.2%) treated for high astigmatism (P=0.02) had lost two or more lines of BSCVA after three months. Conclusion: This study is the first of its kind, and our results indicate that SMILE treatment of high degree astigmatism is equally accurate and stable...... as treatment of low degree astigmatism. More eyes treated for high degree astigmatism lose two or more lines of BSCVA up to three months after surgery. Keywords Refractive surgery, astigmatism, SMILE......Field: Ophthalmology Introduction: SMILE has proven effective in treatment of myopia and low degrees of astigmatism (less than 2 dioptres (D)), but there are no studies on treatment of high degrees of astigmatism (2 or more D). The aim of this study was to compare results after SMILE treatment...

  18. Treatment Trends for Stage I Testicular Seminoma in an Equal-Access Medical System.

    Science.gov (United States)

    Wingate, Jonathan T; Etzioni, Ruth; Macdonald, Dusten M; Brand, Timothy C

    2016-10-01

    The practice patterns for adjuvant therapies for stage I seminoma are rapidly evolving, and surveillance is currently preferred. How these recommendations have affected contemporary practice in an equal-access US population is unknown. A total of 436 men diagnosed with clinical stage IA-IB seminoma from 2001 to 2011 were identified in the Automated Central Tumor Registry (ACTUR). The ACTUR is the cancer registry system for the Department of Defense. Logistic regression models analyzed the association between patient characteristics and adjuvant therapy. Overall and recurrence-free survival were determined from Kaplan-Meier analysis. The use of adjuvant radiotherapy in this population decreased significantly from 2001 to 2011. In 2001, 83.9% of patients received radiotherapy compared with only 24.0% in 2011. During that period, a concomitant increase occurred in the use of chemotherapy from 0% to 38.0%. A later year of diagnosis was significantly associated with a greater rate of receiving chemotherapy relative to radiotherapy (P associated with the receipt of surveillance (P = .412 for 2006-2011 vs. 2001-2005; odds ratio, 0.83; 95% CI, 0.54-1.29). Black race or age was not significantly associated with adjuvant therapy. With a median follow-up period of 4.7 years, the 5-year overall and recurrence-free survival rates were 98.0% and 77.0%, respectively. The use of adjuvant radiotherapy has been replaced by chemotherapy for clinical stage I testicular seminoma in an equal-access system. The lack of an increase in active surveillance in our cohort might represent overtreatment of the population. Published by Elsevier Inc.

  19. Low and high acetate amendments are equally as effective at promoting complete dechlorination of trichloroethylene (TCE).

    Science.gov (United States)

    Wei, Na; Finneran, Kevin T

    2013-06-01

    Experiments with trichloroethylene-contaminated aquifer material demonstrated that TCE, cis-DCE, and VC were completely degraded with concurrent Fe(III) or Fe(III) and sulfate reduction when acetate was amended at stoichiometric concentration; competing TEAPs did not inhibit ethene production. Adding 10× more acetate did not increase the rate or extent of TCE reduction, but only increased methane production. Enrichment cultures demonstrated that ~90 μM TCE or ~22 μM VC was degraded primarily to ethene within 20 days with concurrent Fe(III) or Fe(III) + sulfate reduction. The dechlorination rates were comparable between the low and high acetate concentrations (0.36 vs 0.34 day(-1), respectively), with a slightly slower rate in the 10× acetate amended incubations. Methane accumulated to 13.5 (±0.5) μmol/tube in the TCE-degrading incubations with 10× acetate, and only 1.4 (±0.1) μmol/tube with low acetate concentration. Methane accumulated to 16 (±1.5) μmol/tube in VC-degrading enrichment with 10× acetate and 2 (±0.1) μmol/tube with stoichiometric acetate. The estimated fraction of electrons distributed to methanogenesis increased substantially when excessive acetate was added. Quantitative PCR analysis indicated that 10× acetate did not enhance Dehalococcoides biomass but rather increased the methanogen abundance by nearly one order of magnitude compared to that with stoichiometric acetate. The data suggest that adding low levels of substrate may be equally if not more effective as high concentrations, without producing excessive methane. This has implications for field remediation efforts, in that adding excess electron donor may not benefit the reactions of interest, which in turn will increase treatment costs without direct benefit to the stakeholders.

  20. Characterization of an acidification and equalization tank (AET operating as a primary treatment of swine liquid effluent

    Directory of Open Access Journals (Sweden)

    Fabrício Motteran

    2013-06-01

    Full Text Available This work evaluated the potential of the acidification equalization tank (AET used as a primary treatment unit, treating the hog farming wastewater. The treatment system consisted of a degritter with a triangular-notch weir, for measuring the flow, a static sieve, and an acidification and equalization tank (AET, an anaerobic baffled reactor (ABR, an upflow anaerobic sludge blanket (UASB reactor, a settling tank, a greenhouse for fertirrigation and two infiltration ponds. The AET had a net capacity of 8,000 liters, internally covered with asphalt blanket, worked based on surface loading rates application. The unit operated continuously, with its flow varying from 0.1 to 10 L s-1. To determine the efficiency, the following parameters were measured: pH; COD; BOD; volatile and fixed solids; settleable solids; total, intermediate and partial alkalinity and total acidity. The COD removal varied from 5 to 20%. The average pH was 7.3 and the total, intermediate and partial alkalinity in the effluent, were 1919, 846, 1197 mg L-1, respectively. The total acidity in the effluent was 34 mg L-1. The influent and effluent total BOD and oil & grease concentrations were 3436 and 3443 mg L-1, and 415 and 668 mg L-1, respectively. It was found that the AET worked properly concerning the acidification, equalization and sedimentation processes, confirming low cost of implementation and easy operation, when compared to other traditional decanters.

  1. The white (male) effect and risk perception: can equality make a difference?

    Science.gov (United States)

    Olofsson, Anna; Rashid, Saman

    2011-06-01

    Previous research has shown that white males have a relatively low perception of risks, known as the "white male effect" (WME). Many of the explanations of this effect refer to the privileged position of this particular demographic group in society, adducing white males' socio-economic resources, sense of control, worldviews, etc. It can thus be argued that inequality leads women and ethnic minorities to have higher risk perception than men and the ethnic majority. Therefore, the aim of this study is to investigate the WME in a gender-equal country, Sweden, to see if the pattern is similar to previous studies from the comparably less gender-equal United States. The empirical analyses are based on a national survey (n= 1,472) on the perception of risk conducted in Sweden in the winter of 2005. The results show that in Sweden there is no significant difference between men and women in risk perception, while people with foreign backgrounds perceive risks higher than native people. The chief finding is that there is no WME in Sweden, which we concluded results from the relative equality between the sexes in the country. On the other hand, ethnicity serves as a marker of inequality and discrimination in Sweden. Consequently, ethnicity, in terms of foreign background, mediates inequality, resulting in high risk perception. Equality therefore seems to be a fruitful concept with which to examine differences in risk perception between groups in society, and we propose that the "societal inequality effect" is a more proper description than the "WME." © 2011 Society for Risk Analysis.

  2. Equal opportunities in diversity

    CERN Multimedia

    Laëtitia Pedroso

    2010-01-01

    Promoting equal opportunities at CERN and advising the Director-General on all related matters is the task of the Equal Opportunities Officer, Doris Chromek-Burckhart, and Tim Smith, chair of the Equal Opportunities Advisory Panel. Changes are being introduced: in future, the focus of their work will be broadened to cover all aspects of diversity promotion.   The term "equal opportunities" has always been broader in scope than the equal treatment of men and women but this is what it has traditionally been confined to in practice. "We wanted to change how people see our mission", explains Doris Chromek-Burckhart. The word "diversity" has much wider connotations than "equal opportunities" and makes it clearer that we are also dealing with differences in nationality, religion, age, culture and physical ability”. Getting away from the old clichés is vital to ensuring equal treatment for everyone. The diversit...

  3. Naloxone and epinephrine are equally effective for cardiopulmonary resuscitation in a rat asphyxia model.

    Science.gov (United States)

    Chen, M-H; Xie, L; Liu, T-W; Song, F-Q; He, T

    2006-10-01

    It is not known whether naloxone is as efficacious as epinephrine during cardiopulmonary resuscitation (CPR). The aim of the study was to compare the effects of naloxone and epinephrine on the outcomes of CPR following asphyxial cardiac arrest in rats. Cardiac arrest was induced with asphyxia by clamping the tracheal tubes. Twenty-four Sprague-Dawley rats were randomized prospectively into a saline group (treated with normal saline, 1 ml intravenously, n = 8), an epinephrine group (treated with epinephrine, 0.04 mg/kg intravenously, n = 8) or a naloxone group (treated with naloxone, 1 mg/kg intravenously, n = 8) in a blind fashion during resuscitation after asphyxial cardiac arrest. After 5 min of untreated cardiac arrest, conventional manual CPR was started and each drug was administered at the same time. The rates of restoration of spontaneous circulation (ROSC) were one of eight (12.5%), seven of eight (87.5%) and seven of eight (87.5%) in the saline, epinephrine and naloxone groups, respectively. The rates of ROSC in the epinephrine and naloxone groups were equal and significantly greater than that in the saline group (P = 0.01 and P = 0.01, respectively). The administration of naloxone or epinephrine alone may increase the resuscitation rate, and both drugs are equally effective for CPR in a rat asphyxia model. However, the mechanism by which naloxone produces its efficacy during CPR remains unclear and further experimentation will be necessary.

  4. Not All Education is Equally Liberal: The Effects of Science Education on Political Attitudes

    Directory of Open Access Journals (Sweden)

    Christine Ma-Kellams

    2014-07-01

    Full Text Available Education stands as a potent predictor of political attitudes; however, the underlying mechanisms and moderators of this relationship are not well-understood. We hypothesize that the liberalizing effect of education is moderated by discipline, and that the scientific ethos that serves to guide empirical inquiries facilitates the development of more liberal political attitudes via concerns about fairness and equality. As predicted, being educated in a science-related discipline, as opposed to a non-science discipline, was associated with greater political liberalism; importantly, this effect could not be accounted for by self-selection (Study 1. Furthermore, concerns about fairness and equality, as captured by an individual’s social dominance orientation, mediated the relationship between studying science and political liberalism (Study 2. Study 3 replicated these findings and attest to their generalizability. Study 4 directly assessed the underlying mechanism, endorsement of the scientific ethos, and replicated the mediational model; those who endorsed the scientific ethos more strongly reported more liberal political attitudes, and this was mediated by their lower social dominance orientation.

  5. Equality = Inequality

    DEFF Research Database (Denmark)

    Khaled, Rilla

    2011-01-01

    A number of design and development methods, including participatory design and agile software development, are premised on an underlying assumption of equality amongst relevant stakeholders such as designers, developers, product owners, and end users. Equality, however, is not a straightforwardly...... an ethnography conducted during the workshop, including location, cultural and classroom hierarchies, gender, “girl games”, stakeholders and boundaries, and risk mitigation....

  6. The effectiveness of stuttering treatments in Germany.

    Science.gov (United States)

    Euler, Harald A; Lange, Benjamin P; Schroeder, Sascha; Neumann, Katrin

    2014-03-01

    Persons who stutter (PWS) should be referred to the most effective treatments available, locally or regionally. A prospective comparison of the effects of the most common stuttering treatments in Germany is not available. Therefore, a retrospective evaluation by clients of stuttering treatments was carried out. The five most common German stuttering treatments (231 single treatment cases) were rated as to their perceived effectiveness, using a structured questionnaire, by 88 PWS recruited through various sources. The participants had received between 1 and 7 treatments for stuttering. Two stuttering treatments (stuttering modification, fluency shaping) showed favorable and three treatments (breathing therapy, hypnosis, unspecified logopedic treatment) showed unsatisfactory effectiveness ratings. The effectiveness ratings of stuttering modification and fluency shaping did not differ significantly. The three other treatments were equally ineffective. The differences between the effective and ineffective treatments were of large effect sizes. The typical therapy biography begins in childhood with an unspecified logopedic treatment administered extensively in single and individual sessions. Available comparisons showed intensive or interval treatments to be superior to extensive treatments, and group treatments to be superior to single client treatments. The stuttering treatment most often prescribed in Germany, namely a weekly session of individual treatment by a speech-language pathologist, usually with an assorted package of mostly unknown components, is of limited effectiveness. Better effectiveness can be expected from fluency shaping or stuttering modification approaches, preferably with an intensive time schedule and with group sessions. Readers will be able to: (a) discuss the five most prevalent stuttering treatments in Germany; (b) summarize the effectiveness of these treatments; and (c) describe structural treatment components that seem to be preferable

  7. Effect of friction stirring on microstructure in equal channel angular pressed aluminum alloys

    Energy Technology Data Exchange (ETDEWEB)

    Sato, Y.S.; Urata, M.; Kokawa, H.; Ikeda, K. [Dept. of Materials Processing, Graduate School of Engineering, Tohoku Univ., Aoba-yama, Sendai (Japan)

    2003-07-01

    Friction stir welding (FSW) was applied to equal channel angular (ECA) pressed aluminum (Al) alloys with high strength and toughness, and the effect of FSW on microstructure and the hardness profile in ECA-pressed alloys was examined. In the weld of ECA-pressed Al alloy 1050 and 5083, the stir zone had roughly the same hardness as the ECA-pressed material, while the hardness was slightly reduced in the thermo-mechanically affected zone (TMAZ). The reduction of hardness in the TMAZ was due to dynamic recovery of dislocation cells of the ECA-pressed material. The addition of Zr to Al suppressed the reduction of hardness in the TMAZ. Consequently, friction stir (FS) weld of Al-Zr alloy retained the hardness of the ECA-pressed material throughout the weld. (orig.)

  8. Effect of equal channel angular pressing on the strength and ductility of an AZ80 alloy

    International Nuclear Information System (INIS)

    Pereira, T S; Chung, C W; Ding, R; Chiu, Y L

    2009-01-01

    Equal channel angular pressing (ECAP) was applied to an extruded AZ80 Mg alloy in order to refine microstructure and enhance mechanical properties. The results show that the initial grain size of 20 μm of the as-extruded samples has been reduced by 75% after the first pass of ECAP, down to about 5 μm. Also as a result of the severe plastic deformation, the intermetallic compound Mg 17 Al 12 , which was distributed along grain boundaries and forms networks before the ECAP, has been re-arranged into a more homogeneous distribution and with a more spherical shape after the ECAP. Although no strengthening effect has been observed, the grain refinement and precipitate fragmentation caused by the ECAP has resulted in a 28% increase in the elongation to failure in tensile tests. Fractography observation and texture measurement have also been carried out.

  9. Effect of area x-ray beam equalization on image quality and dose in digital mammography

    Energy Technology Data Exchange (ETDEWEB)

    Wong, Jerry; Xu Tong; Husain, Adeel; Le, Huy; Molloi, Sabee [Department of Radiological Sciences, University of California, Irvine, CA 92697 (United States)

    2004-08-21

    In mammography, thick or dense breast regions persistently suffer from reduced contrast-to-noise ratio (CNR) because of degraded contrast from large scatter intensities and relatively high noise. Area x-ray beam equalization can improve image quality by increasing the x-ray exposure to under-penetrated regions without increasing the exposure to other breast regions. Optimal equalization parameters with respect to image quality and patient dose were determined through computer simulations and validated with experimental observations on a step phantom and an anthropomorphic breast phantom. Three parameters important in equalization digital mammography were considered: attenuator material (Z = 13-92), beam energy (22-34 kVp) and equalization level. A Mo/Mo digital mammography system was used for image acquisition. A prototype 16 x 16 piston driven equalization system was used for preparing patient-specific equalization masks. Simulation studies showed that a molybdenum attenuator and an equalization level of 20 were optimal for improving contrast, CNR and figure of merit (FOM = CNR{sup 2}/dose). Experimental measurements using these parameters showed significant improvements in contrast, CNR and FOM. Moreover, equalized images of a breast phantom showed improved image quality. These results indicate that area beam equalization can improve image quality in digital mammography.

  10. ECONOMIC EQUALITY OR JUSTICE

    Directory of Open Access Journals (Sweden)

    Ekrem Tufan

    2017-12-01

    Full Text Available From the beginning of economic life, equality has been a matter for human. Intrinsically human has two legs: Selfish and Groupish. Our selfish side does not care equality while Groupish side cares. What about the justice? Does human wants justice more than equalities in economic life? In this research, we have applied a questionnaire to find these two questions answer. As a result we can report that respondents prefer equality rather than justice in negative outcomes. On the other hand, they tend to prefer justice if there is possibility for positive outcomes. We cannot give evidence about gender, education and age differences effect on equality and justice preference.

  11. Are all placebo effects equal? Placebo pills, sham acupuncture, cue conditioning and their association.

    Directory of Open Access Journals (Sweden)

    Jian Kong

    Full Text Available Placebo treatments and healing rituals have been used to treat pain throughout history. The present within-subject crossover study examines the variability in individual responses to placebo treatment with verbal suggestion and visual cue conditioning by investigating whether responses to different types of placebo treatment, as well as conditioning responses, correlate with one another. Secondarily, this study also examines whether responses to sham acupuncture correlate with responses to genuine acupuncture. Healthy subjects were recruited to participate in two sequential experiments. Experiment one is a five-session crossover study. In each session, subjects received one of four treatments: placebo pills (described as Tylenol, sham acupuncture, genuine acupuncture, or no treatment rest control condition. Before and after each treatment, paired with a verbal suggestion of positive effect, each subject's pain threshold, pain tolerance, and pain ratings to calibrated heat pain were measured. At least 14 days after completing experiment one, all subjects were invited to participate in experiment two, during which their analgesic responses to conditioned visual cues were tested. Forty-eight healthy subjects completed experiment one, and 45 completed experiment two. The results showed significantly different effects of genuine acupuncture, placebo pill and rest control on pain threshold. There was no significant association between placebo pills, sham acupuncture and cue conditioning effects, indicating that individuals may respond to unique healing rituals in different ways. This outcome suggests that placebo response may be a complex behavioral phenomenon that has properties that comprise a state, rather than a trait characteristic. This could explain the difficulty of detecting a signature for "placebo responders." However, a significant association was found between the genuine and sham acupuncture treatments, implying that the non

  12. Pioneers and laggards - is the effect of gender equality on health dependent on context?

    Science.gov (United States)

    Backhans, Mona Christina; Burström, Bo; Lindholm, Lars; Månsdotter, Anna

    2009-04-01

    This study combines data at individual and area level to examine interactions between equality within couples and gender equality in the municipality in which individuals live. The research question is whether the context impacts on the association between gender equality and health. The material consists of data on 37,423 men and 37,616 women in 279 Swedish municipalities, who had their first child in 1978. The couples were classified according to indicators of their level of gender equality in 1980 in the public sphere (occupation and income) and private sphere (child care leave and parental leave) compared to that of their municipality. The health outcome is compensated days from sickness insurance during 1986-1999 with a cut-off at the 85% percentile. Data were analysed using logistic regression with the overall odds as reference. The results concerning gender equality in the private sphere show that among fathers, those who are equal in an equal municipality have lower levels of sick leave than the average while laggards (less equal than their municipality) and modest laggards have higher levels. In the public sphere, pioneers (more equal t han their municipality) fare better than the average while laggards fare worse. For mothers, those who are traditional in their roles in the public sphere are protected from high levels of sick leave, while the reverse is true for those who are equal. Traditional mothers in a traditional municipality have the lowest level of sick leave and pioneers the highest. These results show that there are distinct benefits as well as disadvantages to being a gender pioneer and/or a laggard in comparison to your municipality. The associations are markedly different for men and women.

  13. Effect of equal channel angular pressing on in vitro degradation of LAE442 magnesium alloy

    Energy Technology Data Exchange (ETDEWEB)

    Minárik, Peter, E-mail: peter.minarik@mff.cuni.cz [Department of Physics of Materials, Faculty of Mathematics and Physics, Charles University, Ke Karlovu 5, 121 16 Prague 2 (Czech Republic); Jablonská, Eva [Department of Biochemistry and Microbiology, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague 6 (Czech Republic); Král, Robert [Department of Physics of Materials, Faculty of Mathematics and Physics, Charles University, Ke Karlovu 5, 121 16 Prague 2 (Czech Republic); Lipov, Jan; Ruml, Tomáš [Department of Biochemistry and Microbiology, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague 6 (Czech Republic); Blawert, Carsten [Helmholtz-Zentrum Geesthacht, Zentrum für Material- und Küstenforschung GmbH, Institut für Werkstoffforschung, Max-Planck-Straße 1, Geesthacht (Germany); Hadzima, Branislav [University of Žilina, Univerzitná 8215/1, 010 26 Žilina (Slovakia); Chmelík, František [Department of Physics of Materials, Faculty of Mathematics and Physics, Charles University, Ke Karlovu 5, 121 16 Prague 2 (Czech Republic)

    2017-04-01

    Effect of processing by equal channel angular pressing (ECAP) on the degradation behaviour of extruded LAE442 magnesium alloy was investigated in a 0.1 M NaCl solution, Kirkland's biocorrosion medium (KBM) and Minimum Essential Medium (MEM), both with and without 10% of foetal bovine serum (FBS). Uniform degradation of as extruded and ECAP processed samples in NaCl solution was observed, nevertheless higher corrosion resistance was found in the latter material. The increase of corrosion resistance due to ECAP was observed also after 14-days immersion in all media used. Higher compactness of the corrosion layer formed on the samples after ECAP was responsible for the observed decrease of corrosion resistance, which was proven by scanning electron microscope investigation. Lower corrosion rate in media with FBS was observed and was explained by additional effect of protein incorporation on the corrosion layer stability. A cytotoxicity test using L929 cells was carried out to investigate possible effect of processing on the cell viability. Sufficient cytocompatibility of the extruded samples was observed with no adverse effects of the subsequent ECAP processing. In conclusion, this in vitro study proved that the degradation behaviour of the LAE442 alloy could be improved by subsequent ECAP processing and this material is a good candidate for future in vivo investigation. - Highlights: • ECAP processing decelerates the corrosion rate of the LAE442 magnesium alloy. • Corrosion layers formed on the samples after ECAP have higher compactness. • No cytotoxic effect of extracts prepared from LAE442 after both types of processing was observed.

  14. Effect of equal channel angular pressing on in vitro degradation of LAE442 magnesium alloy

    International Nuclear Information System (INIS)

    Minárik, Peter; Jablonská, Eva; Král, Robert; Lipov, Jan; Ruml, Tomáš; Blawert, Carsten; Hadzima, Branislav; Chmelík, František

    2017-01-01

    Effect of processing by equal channel angular pressing (ECAP) on the degradation behaviour of extruded LAE442 magnesium alloy was investigated in a 0.1 M NaCl solution, Kirkland's biocorrosion medium (KBM) and Minimum Essential Medium (MEM), both with and without 10% of foetal bovine serum (FBS). Uniform degradation of as extruded and ECAP processed samples in NaCl solution was observed, nevertheless higher corrosion resistance was found in the latter material. The increase of corrosion resistance due to ECAP was observed also after 14-days immersion in all media used. Higher compactness of the corrosion layer formed on the samples after ECAP was responsible for the observed decrease of corrosion resistance, which was proven by scanning electron microscope investigation. Lower corrosion rate in media with FBS was observed and was explained by additional effect of protein incorporation on the corrosion layer stability. A cytotoxicity test using L929 cells was carried out to investigate possible effect of processing on the cell viability. Sufficient cytocompatibility of the extruded samples was observed with no adverse effects of the subsequent ECAP processing. In conclusion, this in vitro study proved that the degradation behaviour of the LAE442 alloy could be improved by subsequent ECAP processing and this material is a good candidate for future in vivo investigation. - Highlights: • ECAP processing decelerates the corrosion rate of the LAE442 magnesium alloy. • Corrosion layers formed on the samples after ECAP have higher compactness. • No cytotoxic effect of extracts prepared from LAE442 after both types of processing was observed.

  15. The effect of gender equality on happiness: Statistical modeling and analysis.

    Science.gov (United States)

    Qian, Ge

    2017-02-01

    In this article, the researcher presents linear regression models that describe how five gender-equality indexes affect individuals' perceptions of well-being and happiness, controlling for their economic income and weighed by the population of the countries that contribute to the models. The logical premise of this study is that gender equality is not only favorable for women, but it is also conducive to fostering the greatest level of happiness for all people. The researcher believes that most findings confirmed this assumption and the opinion of John Stuart Mill regarding gender equality, while two exceptions are explained by social quality theory and the male breadwinner model.

  16. The Effects of Discrimination on Job Satisfaction in the Military: Comparing Evidence from the Armed Forces Equal Opportunity Survey and the Military Equal Opportunity Climate Survey

    National Research Council Canada - National Science Library

    Stewart, James

    2001-01-01

    ...) are analyzed separately. Comparison of the two analyses confirms positive relations among racial/ethnic groups or, more generally, a healthy climate for equal opportunity is associated with higher levels of satisfaction...

  17. A comparative study on the efficacy of 10% hypertonic saline and equal volume of 20% mannitol in the treatment of experimentally induced cerebral edema in adult rats

    Directory of Open Access Journals (Sweden)

    Fang Ming

    2010-12-01

    Full Text Available Abstract Background Hypertonic saline and mannitol are commonly used in the treatment of cerebral edema and elevated intracranial pressure (ICP at present. In this connection, 10% hypertonic saline (HS alleviates cerebral edema more effectively than the equal volume of 20% mannitol. However, the exact underlying mechanism for this remains obscure. This study aimed to explore the possible mechanism whereby 10% hypertonic saline can ameliorate cerebral edema more effectively than mannitol. Results Adult male Sprague-Dawley (SD rats were subjected to permanent right-sided middle cerebral artery occlusion (MCAO and treated with a continuous intravenous infusion of 10% HS, 20% mannitol or D-[1-3H(N]-mannitol. Brain water content (BWC as analyzed by wet-to-dry ratios in the ischemic hemisphere of SD rats decreased more significantly after 10% HS treatment compared with 20% mannitol. Concentration of serum Na+ and plasma crystal osmotic pressure of the 10% HS group at 2, 6, 12 and 18 h following permanent MCAO increased significantly when compared with 20% mannitol treated group. Moreover, there was negative correlation between the BWC of the ipsilateral ischemic hemisphere and concentration of serum Na+, plasma crystal osmotic pressure and difference value of concentration of serum Na+ and concentration of brain Na+ in ipsilateral ischemic hemisphere in the 10% HS group at the various time points after MCAO. A remarkable finding was the progressive accumulation of mannitol in the ischemic brain tissue. Conclusions We conclude that 10% HS is more effective in alleviating cerebral edema than the equal volume of 20% mannitol. This is because 10% HS contributes to establish a higher osmotic gradient across BBB and, furthermore, the progressive accumulation of mannitol in the ischemic brain tissue counteracts its therapeutic efficacy on cerebral edema.

  18. Effect of Equal-Channel Angular Pressing on Pitting Corrosion of Pure Aluminum

    Directory of Open Access Journals (Sweden)

    Injoon Son

    2012-01-01

    Full Text Available The effect of equal-channel angular pressing (ECAP on the pitting corrosion of pure Al was investigated using electrochemical techniques in solutions containing 0.1 m mol·dm−3 of Na2SO4 and 8.46 mol·dm−3 of NaCl (300 ppm Cl− and followed by surface analysis. The potential for pitting corrosion of pure Al was clearly shifted in the noble direction by the ECAP process indicating that this process improves resistance to pitting corrosion. The time dependence of corrosion potential and the anodic potential at 1 A·m−2 revealed that the rate of formation of Al oxide films increased due to a decrease in the grain size of the Al after ECAP. Since there exists a negligible amount of impurity precipitates in pure Al, the improvement in pitting corrosion resistance of pure Al by ECAP appears to be attributable to an increase in the rate of formation of Al oxide films.

  19. Unjust Equalities

    DEFF Research Database (Denmark)

    Albertsen, Andreas; Midtgaard, Søren Flinch

    2014-01-01

    In the luck egalitarian literature, one influential formulation of luck egalitarianism does not specify whether equalities that do not reflect people’s equivalent exercises of responsibility are bad with regard to inequality. This equivocation gives rise to two competing versions of luck egalitar......In the luck egalitarian literature, one influential formulation of luck egalitarianism does not specify whether equalities that do not reflect people’s equivalent exercises of responsibility are bad with regard to inequality. This equivocation gives rise to two competing versions of luck....... The symmetrical view, we argue, is by far the more compelling, both by internal luck egalitarian standards and in light of the external rightist emphasis on choice and responsibility to which luck egalitarianism may partly be seen as a response. Our main case for the symmetrical view is that when some people...

  20. Test of equal effect per fraction and estimation of initial clonogen number in microcolony assays of survival after fractionated irradiation

    International Nuclear Information System (INIS)

    Thames, H.D.; Withers, H.R.

    1980-01-01

    In the use of multifraction microcolony assays to infer the low-dose response of in situ renewal systems such as intestinal crypts, the assumption of equal effect per dose fraction is required. Moreover, the construction of a cell-survival curve requires knowledge of the initial count of cells capable of repopulating each renewal structure. We describe a method of designing fractionation protocols which provides a regression estimate of the initial number of clonogens per renewal structure and a test of the hypothesis of equal effect per fraction. The essential factor in the experimental design is the use of common dose fractions (use of the same dose per fraction in series with different numbers of fractions). Applications of the method to data for which the assumption of equal effect per fraction holds (four-hour fractionation interval murine testis study) and does not hold (one-hour fractionation interval murine jejunal crypt study) are presented. (author)

  1. Cross-national variation in the size of sex differences in values: effects of gender equality.

    Science.gov (United States)

    Schwartz, Shalom H; Rubel-Lifschitz, Tammy

    2009-07-01

    How does gender equality relate to men's and women's value priorities? It is hypothesized that, for both sexes, the importance of benevolence, universalism, stimulation, hedonism, and self-direction values increases with greater gender equality, whereas the importance of power, achievement, security, and tradition values decreases. Of particular relevance to the present study, increased gender equality should also permit both sexes to pursue more freely the values they inherently care about more. Drawing on evolutionary and role theories, the authors postulate that women inherently value benevolence and universalism more than men do, whereas men inherently value power, achievement, and stimulation more than women do. Thus, as gender equality increases, sex differences in these values should increase, whereas sex differences in other values should not be affected by increases in gender equality. Studies of 25 representative national samples and of students from 68 countries confirmed the hypotheses except for tradition values. Implications for cross-cultural research on sex differences in values and traits are discussed. (PsycINFO Database Record (c) 2009 APA, all rights reserved).

  2. Photochemical internalization (PCI) of bleomycin is equally effective in two dissimilar leiomyosarcoma xenografts in athymic mice.

    Science.gov (United States)

    Sellevold, Simen; Peng, Qian; Fremstedal, Ane Sofie Viset; Berg, Kristian

    2017-12-01

    Photochemical internalization (PCI) is a novel technique for delivery of active macromolecules into cancerous cells, via light activation of a specific photosensitizer and a low dose systemic drug. Numerous pre-clinical studies and one clinical trial have confirmed the treatment potential in carcinomas. Soft tissue sarcomas are rare and generally resistant to radio- and chemotherapy. Due to treatment resistance and surgical morbidity in sarcoma care, we seek to increase knowledge on PCI effects in sarcomas by studying two different, but closely related leiomyosarcomas. MES-SA and SK-LMS-1 tumours were established in the leg muscles of athymic mice. Treatment effects after AlPcS 2a -PCI of bleomycin, PCI with no drug (photodynamic therapy, PDT) and control groups were evaluated by: 1) assessment of tumour growth, 2) uptake of contrast agent during MRI and 3) histopathology. PCI of bleomycin induced a similar and significant increase in time to reach the end point in both tumour models, while neither responded to AlPcS 2a -PDT. In the MES-SA tumours PCI reduced the growth rate, while in the SK-LMS-1 tumours the growth was blocked for 12days followed by exponential growth close to that of untreated tumours. SK-LMS-1 tumours were more homogenously and better vascularized than MES-SA. After PCI the vascular shutdown was more complete in the SK-LMS-1 tumours than in the MES-SA tumours. AlPcS2a-based PCI, but not PDT, induced significant tumour growth delay in the evaluated sarcomas. Cellular responsiveness to bleomycin and tumour vascularity are identified as predictive markers for PCI treatment effects. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Outcome for stage II and III rectal and colon cancer equally good after treatment improvement over three decades.

    Science.gov (United States)

    Fischer, Joern; Joern, Fischer; Hellmich, Gunter; Gunter, Hellmich; Jackisch, Thomas; Thomas, Jackisch; Puffer, Erik; Erik, Puffer; Zimmer, Jörg; Jörg, Zimmer; Bleyl, Dorothea; Dorothea, Bleyl; Kittner, Thomas; Thomas, Kittner; Witzigmann, Helmut; Helmut, Witzigmann; Stelzner, Sigmar; Sigmar, Stelzner

    2015-06-01

    This study aimed to investigate the outcome for stage II and III rectal cancer patients compared to stage II and III colonic cancer patients with regard to 5-year cause-specific survival (CSS), overall survival, and local and combined recurrence rates over time. This prospective cohort study identified 3,355 consecutive patients with adenocarcinoma of the colon or rectum and treated in our colorectal unit between 1981 and 2011, for investigation. The study was restricted to International Union Against Cancer (UICC) stages II and III. Postoperative mortality and histological incomplete resection were excluded, which left 995 patients with colonic cancer and 726 patients with rectal cancer for further analysis. Five-year CSS rates improved for colonic cancer from 65.0% for patients treated between 1981 and 1986 to 88.1% for patients treated between 2007 and 2011. For rectal cancer patients, the respective 5-year CSS rates improved from 53.4% in the first observation period to 89.8% in the second one. The local recurrence rate for rectal cancer dropped from 34.2% in the years 1981-1986 to 2.1% in the years 2007-2011. In the last decade of observation, prognosis for rectal cancer was equal to that for colon cancer (CSS 88.6 vs. 86.7%, p = 0.409). Survival of patients with colon and rectal cancer has continued to improve over the last three decades. After major changes in treatment strategy including introduction of total mesorectal excision and neoadjuvant (radio)chemotherapy, prognosis for stage II and III rectal cancer is at least as good as for stage II and III colonic cancer.

  4. Early Understanding of Equality

    Science.gov (United States)

    Leavy, Aisling; Hourigan, Mairéad; McMahon, Áine

    2013-01-01

    Quite a bit of the arithmetic in elementary school contains elements of algebraic reasoning. After researching and testing a number of instructional strategies with Irish third graders, these authors found effective methods for cultivating a relational concept of equality in third-grade students. Understanding equality is fundamental to algebraic…

  5. Equal Opportunities Questionnaire

    CERN Multimedia

    2007-01-01

    The initiative to promote Equal Opportunities at CERN started in 1993. The first Equal Opportunities Officer was appointed in 1996 followed by the creation of the Equal Opportunities Advisory Panel in 1998. Initially the concern was mainly the fair treatment of women in the work-place. Today the emphasis has evolved to ensuring that diversity is used to increase creativity and productivity in the work-place. In order to ensure that all aspects of Equal Opportunities and Diversity are covered, CERN’s Equal Opportunities team has prepared a survey to obtain your input. Your answers are confidential and will only be used for generating statistics. The questionnaire is on-line and can be accessed via: https://espace.cern.ch/EOQ. We hope that you will take a few minutes of your time to give your input and would be grateful if you could reply before 15/10/07. For further information about Equal Opportunities at CERN see: http://cern.ch/equal-opportunities The Equal Opportuni...

  6. Effect of equal-channel angular pressing on the creep resistance of precipitation-strengthened alloys

    Czech Academy of Sciences Publication Activity Database

    Sklenička, Václav; Král, Petr; Dvořák, Jiří; Kvapilová, Marie; Kawasaki, M.; Langdon, T. G.

    667-669, - (2011), s. 897-902 ISSN 0255-5476. [NanoSPD5 - International Conference on Nanomaterials by Severe Plastic Deformation /5./. Nanjing, 21.03.2011-25.03.2011] Institutional research plan: CEZ:AV0Z20410507 Keywords : creep * equal-channel angular pressing * precipitation- strength ened alloys * creep damage Subject RIV: JG - Metallurgy

  7. Effects of equal channel angular extrusion on microstructure, strength and ballistic performance of AA5754 plates

    DEFF Research Database (Denmark)

    Mishin, Oleg; Hong, Chuanshi; Toftegaard, Helmuth Langmaack

    2014-01-01

    The microstructure, hardness, tensile properties and ballistic performance have been investigated in thick plates of the AA5754 alloy both in a coarse-grained as-received condition and after 4 passes of equal channel angular extrusion (ECAE) conducted at elevated temperatures. It is found that ECAE...

  8. Dietary Wheat Bran Oil Is Equally as Effective as Rice Bran Oil in Reducing Plasma Cholesterol.

    Science.gov (United States)

    Lei, Lin; Chen, Jingnan; Liu, Yuwei; Wang, Lijun; Zhao, Guohua; Chen, Zhen-Yu

    2018-03-21

    Rice bran oil (RBO) possesses a plasma cholesterol-lowering activity, while effect of wheat bran oil (WBO) on plasma cholesterol remains unknown. The present study compared the cholesterol-lowering activity of WBO with that of RBO in hamsters. Fifty-four male hamsters were divided into seven groups fed either a noncholesterol diet (NCD) or one of six high-cholesterol diets, namely HCD diet (0.2% cholesterol +9.5% lard), HCD+C diet (0.2% cholesterol +9.5% lard +0.5% cholestyramine), WL diet (0.2% cholesterol +4.8% Lard +4.8% WBO), WH diet (0.2% cholesterol +9.5% WBO), RL diet (0.2% cholesterol +4.8% Lard +4.8% RBO), and RH diet (0.2% cholesterol +9.5% RBO). Plasma total cholesterol (TC) in HCD group was 327.4 ± 31.8 mg/dL, while plasma TC in two WBO and two RBO groups was 242.2 ± 20.8, 243.1 ± 31.7, 257.1 ± 16.3, and 243.4 ± 46.0 mg/dL, respectively, leading to a decrease in plasma TC by 22-26% ( P cholesterol-lowering potency was seen between WBO and RBO. Plasma cholesterol-lowering activity of WBO and RBO was accompanied by down-regulation of hepatic 3-hydroxy-3-methylglutaryl-CoA reductase and fatty acid synthase, while up-regulation of cholesterol-7α-hydroxylase. WL, WH, RL, and RH diets increased the fecal excretion of total neutral sterols by 72.8%, 106.9%, 5.4%, and 36.8% ( P cholesterol absorption via down-regulation of intestinal Niemann-Pick C1 like 1 protein, acyl CoA:cholesterol acyltransferase 2, and ATP binding cassette transporter 5. In summary, WBO was equally effective as RBO in decreasing plasma cholesterol in hypercholesterolemia hamsters.

  9. The Counter-Normative Effects of Service-Learning: Fostering Attitudes toward Social Equality through Contact and Autonomy

    Science.gov (United States)

    Brown, Margaret A.; Wymer, Jared D.; Cooper, Cierra S.

    2016-01-01

    Power dynamics are implicated in intergroup prosocial behavior (Nadler & Halabi, 2015). This research investigated two factors that influence the effect of intergroup prosocial behavior on views of social equality: amount of direct intergroup contact and type of helping. Students in a social psychology course (N = 93) were randomly assigned to…

  10. Equal Opportunities Questionnaire

    CERN Multimedia

    2007-01-01

    The initiative to promote Equal Opportunities at CERN started in 1993. The first Equal Opportunities Officer was appointed in 1996, which was followed by the creation of the Equal Opportunities Advisory Panel in 1998. Initially the concern was mainly the fair treatment of women in the work-place. Today the emphasis has evolved to ensuring that diversity is used to increase creativity and productivity in the work-place. In order to ensure that all aspects of Equal Opportunities and Diversity are covered, CERN’s Equal Opportunities team has prepared a survey to obtain your input. Your answers are confidential and will only be used for generating statistics. The questionnaire is on-line and can be accessed via: https://espace.cern.ch/EOQ. We hope that you will take a few minutes of your time to give your input and would be grateful if you could reply before 15/10/07. For further information about Equal Opportunities at CERN see: http://cern.ch/equal-opportunities The Equa...

  11. THE EFFECTS OF HOSPITAL QUALITY OF CARE ON PATIENT BELONGING: STRUCTURAL EQUALITY MODEL AND MEDIATION

    Directory of Open Access Journals (Sweden)

    Ali Rıza FİRUZAN

    2017-09-01

    Full Text Available The aim of the study is to measure the effects of perceived and expected service quality levels on patient loyalty. In total, 370 patients participated in this research. The Structural Equation Modeling (SEM method to test the causal relationship model. The corresponding model in the study emerged as acceptable fit with the model. The result of the study indicate that perceived service quality and patient loyalty are statistically significant and positively related to each other. Additionally, perceived service quality has found to be an important mediator between expected service quality and patient loyalty. After patients have treatment in corresponding hospital, they have been affected by service quality as mush as cost of medication. As patient satisfaction increases, their loyalty increases. It is suggested to hospital management that they might course of action to patients for improving Reliability and Assurance SERVQUAL factors

  12. Effects of pulvinar inactivation on spatial decision-making between equal and asymmetric reward options.

    Science.gov (United States)

    Wilke, Melanie; Kagan, Igor; Andersen, Richard A

    2013-08-01

    The ability to selectively process visual inputs and to decide between multiple movement options in an adaptive manner is critical for survival. Such decisions are known to be influenced by factors such as reward expectation and visual saliency. The dorsal pulvinar connects to a multitude of cortical areas that are involved in visuospatial memory and integrate information about upcoming eye movements with expected reward values. However, it is unclear whether the dorsal pulvinar is critically involved in spatial memory and reward-based oculomotor decision behavior. To examine this, we reversibly inactivated the dorsal portion of the pulvinar while monkeys performed a delayed memory saccade task that included choices between equally or unequally rewarded options. Pulvinar inactivation resulted in a delay of saccade initiation toward memorized contralesional targets but did not affect spatial memory. Furthermore, pulvinar inactivation caused a pronounced choice bias toward the ipsilesional hemifield when the reward value in the two hemifields was equal. However, this choice bias could be alleviated by placing a high reward target into the contralesional hemifield. The bias was less affected by the manipulation of relative visual saliency between the two competing targets. These results suggest that the dorsal pulvinar is involved in determining the behavioral desirability of movement goals while being less critical for spatial memory and reward processing.

  13. Effect of regimes of equal-channel angular pressing on the superplasticity of aluminium alloy 1420

    International Nuclear Information System (INIS)

    Islamgaliev, R.K.; Yunusova, N.F.; Valiev, R.Z.

    2002-01-01

    Investigation results on the influence of conditions of equal-channel angular pressing (EAP) on structure and superplasticity of aluminium alloy 1420 (Al-5.5%Mg-2.2%Li-0.12%Zr) are reported. It is revealed that the superplasticity of alloy 1420 is determined not only by fine grains (less than 1 μm), but its structural and phase state as well. The structural phase state is shown to be greatly dependent on EAP conditions. In particular, the structure of specimens prepared using the optimal EAP conditions is characterized by a mean grain size (0.8 μm) of the matrix with predominantly high-angle disorientations as well as by presence of secondary phase Al 2 MgLi and AlLi particles with of 0.3 μm and 0.4 μm size respectively. It is shown that the rods with an optimal structural phase state exhibit record-breaking for the alloy elongation to fracture equal to 1620% at 400 Deg C and at strain rate of 10 -2 s -1 [ru

  14. Estimating scaled treatment effects with multiple outcomes.

    Science.gov (United States)

    Kennedy, Edward H; Kangovi, Shreya; Mitra, Nandita

    2017-01-01

    In classical study designs, the aim is often to learn about the effects of a treatment or intervention on a single outcome; in many modern studies, however, data on multiple outcomes are collected and it is of interest to explore effects on multiple outcomes simultaneously. Such designs can be particularly useful in patient-centered research, where different outcomes might be more or less important to different patients. In this paper, we propose scaled effect measures (via potential outcomes) that translate effects on multiple outcomes to a common scale, using mean-variance and median-interquartile range based standardizations. We present efficient, nonparametric, doubly robust methods for estimating these scaled effects (and weighted average summary measures), and for testing the null hypothesis that treatment affects all outcomes equally. We also discuss methods for exploring how treatment effects depend on covariates (i.e., effect modification). In addition to describing efficiency theory for our estimands and the asymptotic behavior of our estimators, we illustrate the methods in a simulation study and a data analysis. Importantly, and in contrast to much of the literature concerning effects on multiple outcomes, our methods are nonparametric and can be used not only in randomized trials to yield increased efficiency, but also in observational studies with high-dimensional covariates to reduce confounding bias.

  15. Notes on testing equality and interval estimation in Poisson frequency data under a three-treatment three-period crossover trial.

    Science.gov (United States)

    Lui, Kung-Jong; Chang, Kuang-Chao

    2016-10-01

    When the frequency of event occurrences follows a Poisson distribution, we develop procedures for testing equality of treatments and interval estimators for the ratio of mean frequencies between treatments under a three-treatment three-period crossover design. Using Monte Carlo simulations, we evaluate the performance of these test procedures and interval estimators in various situations. We note that all test procedures developed here can perform well with respect to Type I error even when the number of patients per group is moderate. We further note that the two weighted-least-squares (WLS) test procedures derived here are generally preferable to the other two commonly used test procedures in the contingency table analysis. We also demonstrate that both interval estimators based on the WLS method and interval estimators based on Mantel-Haenszel (MH) approach can perform well, and are essentially of equal precision with respect to the average length. We use a double-blind randomized three-treatment three-period crossover trial comparing salbutamol and salmeterol with a placebo with respect to the number of exacerbations of asthma to illustrate the use of these test procedures and estimators. © The Author(s) 2014.

  16. Cognitive behavioural therapy and mindfulness based stress reduction may be equally effective in reducing anxiety and depression in adults with autism spectrum disorders.

    Science.gov (United States)

    Sizoo, Bram B; Kuiper, Erik

    2017-05-01

    Anxiety and depression co-occur in 50-70% of adults with autism spectrum disorder (ASD) but treatment methods for these comorbid problems have not been systematically studied. Recently, two ASD-tailored protocols were published: mindfulness based stress reduction (MBSR) and cognitive behavioural therapy (CBT). We wanted to investigate if both methods are equally effective in reducing anxiety and depression symptoms among adults with ASD. 59 adults with ASD and anxiety or depression scores above 7 on the Hospital Anxiety and Depression Scale, gave informed consent to participate; 27 followed the CBT protocol, and 32 the MBSR treatment protocol. Anxiety and depression scores, autism symptoms, rumination, and global mood were registered at the start, at the end of the 13-week treatment period, and at 3-months follow-up. Irrational beliefs and mindful attention awareness were used as process measures during treatment and at follow-up. Results indicate that both MBSR and CBT are associated with a reduction in anxiety and depressive symptoms among adults with ASD, with a sustained effect at follow-up, but without a main effect for treatment group. A similar pattern was seen for the reduction of autistic symptoms, rumination and the improvement in global mood. There are some indications that MBSR may be preferred over CBT with respect to the treatment effect on anxiety when the scores on measures of irrational beliefs or positive global mood at baseline are high. Mindfulness and cognitive behavioral therapies are both promising treatment methods for reducing comorbid anxiety and depression in adults with ASD. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. A note on discriminating equally optimal semi-Latin squares for sixteen treatments in blocks of size four

    International Nuclear Information System (INIS)

    Chigbu, P.E.

    2004-08-01

    A semi-Latin square for sixteen treatments in blocks of size four is like a 4x4 Latin square except that there exist four treatments in each cell and each of the sixteen treatments occurs once in each row and once in each column. In the literature, three of this class of squares has been found to be A-, D- and E-optimal while an analytic approach has been adopted to further distinguish these optimal ones with the view of identifying the best for experimentation. With this analytic approach the 'best' square was identified - however, it neither provided a common basis for the discrimination of the three squares nor the further classification of the other two good squares. In this paper, therefore, a numerical approach, which basically involves the computation of the generalized inverses of the information matrices of these squares, is adopted. Each of the generalized inverses satisfies the Moore-Penrose inverse properties. Thereafter, a square is considered most preferable among others if it has the maximum number of minimum variance of simple treatment contrasts as well as the minimum number of distinct pairwise treatment variances. Above all, a mini-league table for the three squares is ascertained. (author)

  18. All framing effects are not created equal: Low convergent validity between two classic measurements of framing.

    Science.gov (United States)

    Zhen, Shanshan; Yu, Rongjun

    2016-07-20

    Human risk-taking attitudes can be influenced by two logically equivalent but descriptively different frames, termed the framing effect. The classic hypothetical vignette-based task (Asian disease problem) and a recently developed reward-based gambling task have been widely used to assess individual differences in the framing effect. Previous studies treat framing bias as a stable trait that has genetic basis. However, these two paradigms differ in terms of task domain (loss vs. gain) and task context (vignette-based vs. reward-based) and the convergent validity of these measurements remains unknown. Here, we developed a vignette-based task and a gambling task in both gain and loss domains and tested correlations of the framing effect among these tasks in 159 young adults. Our results revealed no significant correlation between the vignette-based task in the loss domain and the gambling task in the gain domain, indicating low convergent validity. The current findings raise the question of how to measure the framing effect precisely, especially in individual difference studies using large samples and expensive neuroscience methods. Our results suggest that the framing effect is influenced by both task domain and task context and future research should be cautious about the operationalization of the framing effect.

  19. Low-intensity blue-enriched white light (750 lux) and standard bright light (10,000 lux) are equally effective in treating SAD. A randomized controlled study.

    Science.gov (United States)

    Meesters, Ybe; Dekker, Vera; Schlangen, Luc J M; Bos, Elske H; Ruiter, Martine J

    2011-01-28

    Photoreceptor cells containing melanopsin play a role in the phase-shifting effects of short-wavelength light. In a previous study, we compared the standard light treatment (SLT) of SAD with treatment using short-wavelength blue-enriched white light (BLT). Both treatments used the same illuminance (10,000 lux) and were equally highly effective. It is still possible, however, that neither the newly-discovered photoreceptor cells, nor the biological clock play a major role in the therapeutic effects of light on SAD. Alternatively, these effects may at least be partly mediated by these receptor cells, which may have become saturated as a result of the high illuminances used in the therapy. This randomized controlled study compares the effects of low-intensity BLT to those of high-intensity SLT. In a 22-day design, 22 patients suffering from a major depression with a seasonal pattern (SAD) were given light treatment (10,000 lux) for two weeks on workdays. Subjects were randomly assigned to either of the two conditions, with gender and age evenly distributed over the groups. Light treatment either consisted of 30 minutes SLT (5000 °K) with the EnergyLight® (Philips, Consumer Lifestyle) with a vertical illuminance of 10,000 lux at eye position or BLT (17,000 °K) with a vertical illuminance of 750 lux using a prototype of the EnergyLight® which emitted a higher proportion of short-wavelengths. All participants completed questionnaires concerning mood, activation and sleep quality on a daily basis. Mood and energy levels were also assessed on a weekly basis by means of the SIGH-SAD and other assessment tools. On day 22, SIGH-SAD ratings were significantly lower than on day 1 (SLT 65.2% and BLT 76.4%). On the basis of all assessments no statistically significant differences were found between the two conditions. With sample size being small, conclusions can only be preliminary. Both treatment conditions were found to be highly effective. The therapeutic effects of low

  20. Low-intensity blue-enriched white light (750 lux and standard bright light (10 000 lux are equally effective in treating SAD. A randomized controlled study

    Directory of Open Access Journals (Sweden)

    Bos Elske H

    2011-01-01

    Full Text Available Abstract Background Photoreceptor cells containing melanopsin play a role in the phase-shifting effects of short-wavelength light. In a previous study, we compared the standard light treatment (SLT of SAD with treatment using short-wavelength blue-enriched white light (BLT. Both treatments used the same illuminance (10 000 lux and were equally highly effective. It is still possible, however, that neither the newly-discovered photoreceptor cells, nor the biological clock play a major role in the therapeutic effects of light on SAD. Alternatively, these effects may at least be partly mediated by these receptor cells, which may have become saturated as a result of the high illuminances used in the therapy. This randomized controlled study compares the effects of low-intensity BLT to those of high-intensity SLT. Method In a 22-day design, 22 patients suffering from a major depression with a seasonal pattern (SAD were given light treatment (10 000 lux for two weeks on workdays. Subjects were randomly assigned to either of the two conditions, with gender and age evenly distributed over the groups. Light treatment either consisted of 30 minutes SLT (5000°K with the EnergyLight® (Philips, Consumer Lifestyle with a vertical illuminance of 10 000 lux at eye position or BLT (17 000°K with a vertical illuminance of 750 lux using a prototype of the EnergyLight® which emitted a higher proportion of short-wavelengths. All participants completed questionnaires concerning mood, activation and sleep quality on a daily basis. Mood and energy levels were also assessed on a weekly basis by means of the SIGH-SAD and other assessment tools. Results On day 22, SIGH-SAD ratings were significantly lower than on day 1 (SLT 65.2% and BLT 76.4%. On the basis of all assessments no statistically significant differences were found between the two conditions. Conclusion With sample size being small, conclusions can only be preliminary. Both treatment conditions were found

  1. Exercise and 24-h Glycemic Control: Equal Effects for All Type 2 Diabetes Patients?

    NARCIS (Netherlands)

    van Dijk, J.W.; Manders, R.J.F.; Canfora, E.E.; van Mechelen, W.; Hartgens, F.; Stehouwer, C.D.A.; van Loon, L.J.C.

    2013-01-01

    Purpose: We assessed the effect of a single bout of moderate-intensity exercise on subsequent 24-h glycemic control in 60 type 2 diabetes patients. Moreover, we examined whether individual responses to exercise were related to subjects' baseline characteristics, including age, body mass index,

  2. The Equal Pay Act: Higher Education and the Court's View.

    Science.gov (United States)

    Greenlaw, Paul S.; Swanson, Austin D.

    1994-01-01

    Effects of the Equal Pay Act of 1963 for college and university employees are reviewed through an examination of trends in court decisions and legal treatment of the issues. It is concluded that case law has been evolutionary, with concepts of "equal,""work," and others not altered drastically by the courts in recent years.…

  3. SEA effectiveness criteria-equally valid in all countries? The case of Italy

    International Nuclear Information System (INIS)

    Fischer, Thomas B.; Gazzola, Paola

    2006-01-01

    Recent years have seen the introduction of various sets of strategic environmental assessment (SEA) effectiveness criteria in the professional international literature. Content analysis of key international SEA publications suggest that these have been developed based on the experiences of a selected number of countries only, and to date, the question whether they are fully valid in all systems and countries world-wide has not been addressed sufficiently, yet. In this context, the paper discusses the validity of effectiveness criteria for Italy, a country from which authors have only contributed to a very limited extent to the international SEA literature. It is concluded that, particularly in the light of experiences with a 'flexible', but ineffective EIA system, in Italy SEA needs to be applied in a systematic and rigorous manner, aided by strong enforcement mechanisms

  4. Not all nutrition claims are perceived equal: anchoring effects and moderating mechanisms in food advertising.

    Science.gov (United States)

    Paek, Hye-Jin; Yoon, Hye Jin; Hove, Thomas

    2011-03-01

    Despite the increased use of health claims in food advertising, few studies have investigated how specific nutrition claims have differential effects depending on how they are presented. In this context, the current study tests the anchoring hypothesis. Anchoring refers to a common human tendency to evaluate information differently depending on the presence or absence of a numerical "anchor" or reference point. Two (pilot and main) experimental studies explore anchoring effects on audience response to food advertising both directly and moderated by cognitive, motivational, and message factors. The pilot study finds that food product ads employing nutrition claims with an anchor rather than without an anchor generate two results: First, participants perceive the product to have lower fat/lower calorie contents (anchoring hypothesis); second, they prefer the messages with an anchor over those without an anchor. The main study reports that when anchoring is successfully evoked, it produces favorable attitudes toward the ad, favorable attitudes toward the brand, and purchase intention-but only when moderated by health orientation, claim believability, and nutrition knowledge. Practical implications are provided with respect to regulatory guidelines and effective communication strategies for promoting low-fat and low-calorie products in food advertising.

  5. Single- and Dual-Task Balance Training Are Equally Effective in Youth.

    Science.gov (United States)

    Lüder, Benjamin; Kiss, Rainer; Granacher, Urs

    2018-01-01

    Due to maturation of the postural control system and secular declines in motor performance, adolescents experience deficits in postural control during standing and walking while concurrently performing cognitive interference tasks. Thus, adequately designed balance training programs may help to counteract these deficits. While the general effectiveness of youth balance training is well-documented, there is hardly any information available on the specific effects of single-task (ST) versus dual-task (DT) balance training. Therefore, the objectives of this study were (i) to examine static/dynamic balance performance under ST and DT conditions in adolescents and (ii) to study the effects of ST versus DT balance training on static/dynamic balance under ST and DT conditions in adolescents. Twenty-eight healthy girls and boys aged 12-13 years were randomly assigned to either 8 weeks of ST or DT balance training. Before and after training, postural sway and spatio-temporal gait parameters were registered under ST (standing/walking only) and DT conditions (standing/walking while concurrently performing an arithmetic task). At baseline, significantly slower gait speed ( p 0.05, d = 0-0.1) in DT costs for all parameters of secondary task performance during standing and walking. Training produced significant pre-post increases ( p = 0.001; d = 1.47) in secondary task performance while sitting. The observed increase was significantly greater for the ST training group ( p = 0.04; d = 0.81). For standing, no significant changes were found over time irrespective of the experimental group. We conclude that adolescents showed impaired DT compared to ST walking but not standing. ST and DT balance training resulted in significant and similar changes in DT costs during walking. Thus, there appears to be no preference for either ST or DT balance training in adolescents.

  6. Sunk costs equal sunk boats? The effect of entry costs in a transboundary sequential fishery

    DEFF Research Database (Denmark)

    Punt, M. J.

    2017-01-01

    that for other fisheries substantial sunk investments are needed. In this paper I investigate the effect of such sunk entry costs in a sequential fisheries. I model the uncertainty as a shock to the stock dependent fishing costs, in a two player game, where one of the players faces sunk entry costs. I find that......, depending on parameters, sunk costs can i) increase the competitive pressure on the fish stock compared to a game where entry is free ii) act as a deterrence mechanism and iii) act as a commitment device. I conclude that entry costs can play a crucial role because they can change the outcome of the game...

  7. Equal Graph Partitioning on Estimated Infection Network as an Effective Epidemic Mitigation Measure

    Science.gov (United States)

    Hadidjojo, Jeremy; Cheong, Siew Ann

    2011-01-01

    Controlling severe outbreaks remains the most important problem in infectious disease area. With time, this problem will only become more severe as population density in urban centers grows. Social interactions play a very important role in determining how infectious diseases spread, and organization of people along social lines gives rise to non-spatial networks in which the infections spread. Infection networks are different for diseases with different transmission modes, but are likely to be identical or highly similar for diseases that spread the same way. Hence, infection networks estimated from common infections can be useful to contain epidemics of a more severe disease with the same transmission mode. Here we present a proof-of-concept study demonstrating the effectiveness of epidemic mitigation based on such estimated infection networks. We first generate artificial social networks of different sizes and average degrees, but with roughly the same clustering characteristic. We then start SIR epidemics on these networks, censor the simulated incidences, and use them to reconstruct the infection network. We then efficiently fragment the estimated network by removing the smallest number of nodes identified by a graph partitioning algorithm. Finally, we demonstrate the effectiveness of this targeted strategy, by comparing it against traditional untargeted strategies, in slowing down and reducing the size of advancing epidemics. PMID:21799777

  8. Pioglitazone is equally effective for diabetes prevention in older versus younger adults with impaired glucose tolerance.

    Science.gov (United States)

    Espinoza, Sara E; Wang, Chen-Pin; Tripathy, Devjit; Clement, Stephen C; Schwenke, Dawn C; Banerji, Mary Ann; Bray, George A; Buchanan, Thomas A; Henry, Robert R; Kitabchi, Abbas E; Mudaliar, Sunder; Stentz, Frankie B; Reaven, Peter D; DeFronzo, Ralph A; Musi, Nicolas

    2016-12-01

    To determine the efficacy of pioglitazone to prevent type 2 diabetes in older compared to younger adults with pre-diabetes. Six hundred two participants with impaired glucose tolerance (IGT) were randomized in double blind fashion to placebo or pioglitazone for diabetes prevention in the ACT NOW study (NEJM 364:1104-1115, 2011). Cox proportional hazard regression was used to compare time to development of diabetes over a mean of 2 years between older (≥61 years) and younger participants. We compared effects of pioglitazone versus placebo on metabolic profiles, inflammatory markers, adipokines, β cell function (disposition index), insulin sensitivity (Matsuda index), and body composition by ANOVA. Diabetes incidence was reduced by 85 % in older and 69 % in younger subjects (p = 0.41). β cell function (disposition index) increased by 35.0 % in the older and 26.7 % in younger subjects (p = 0.83). Insulin sensitivity (Matsuda index) increased by 3.07 (5.2-fold) in older and by 2.54 (3.8-fold) in younger participants (p = 0.58). Pioglitazone more effectively increased adiponectin in older versus younger subjects (22.9 ± 3.2 μg/mL [2.7-fold] vs. 12.7 ± 1.4 μg/mL [2.2-fold], respectively; p = 0.04). Younger subjects tended to have a greater increase in whole body fat mass compared to older subjects (3.6 vs. 3.1 kg; p = 0.061). Younger and older subjects had similar decreases in bone mineral density (0.018 ± 0.0071 vs. 0.0138 ± 0.021 g/cm 2 ). Younger and older pre-diabetic adults taking pioglitazone had similar reductions in conversion to diabetes and older adults had similar or greater improvements in metabolic risk factors, demonstrating that pioglitazone is useful in preventing diabetes in older adults.

  9. Web-based versus traditional lecture: are they equally effective as a flexible bronchoscopy teaching method?

    Science.gov (United States)

    Mata, Caio Augusto Sterse; Ota, Luiz Hirotoshi; Suzuki, Iunis; Telles, Adriana; Miotto, Andre; Leão, Luiz Eduardo Vilaça

    2012-01-01

    This study compares the traditional live lecture to a web-based approach in the teaching of bronchoscopy and evaluates the positive and negative aspects of both methods. We developed a web-based bronchoscopy curriculum, which integrates texts, images and animations. It was applied to first-year interns, who were later administered a multiple-choice test. Another group of eight first-year interns received the traditional teaching method and the same test. The two groups were compared using the Student's t-test. The mean scores (± SD) of students who used the website were 14.63 ± 1.41 (range 13-17). The test scores of the other group had the same range, with a mean score of 14.75 ± 1. The Student's t-test showed no difference between the test results. The common positive point noted was the presence of multimedia content. The web group cited as positive the ability to review the pages, and the other one the role of the teacher. Web-based bronchoscopy education showed results similar to the traditional live lecture in effectiveness.

  10. Effects of pressing temperature and initial microstructure on the equal channel angular pressing of Ti-6Al-4V alloy

    International Nuclear Information System (INIS)

    Ko, Y.G.; Lee, Y.H.; Jung, W.S.; Shin, D.H.; Lee, C.S.

    2003-01-01

    The effects of pressing temperature and initial microstructure on the equal channel angular (ECA) pressing of Ti-6Al-4V alloy were investigated in this study. The ECA pressing was carried out isothermally with route C at 500 C, 600 C and 700 C for two typical microstructures, i.e., the Widmanstaetten microstructure and the equiaxed microstructure. The results showed that ECA pressing at 600 C and 700 C was successful without producing any noticeable segment at the specimen surfaces, while a large amount of surface segments were produced at 500 C. After 1 pass pressing at 600 C, the equiaxed microstructure showed more uniform material flow at the surface than the Widmanstaetten microstructure. However, this microstructural influence was diminished with increase of the number of the ECA pressing. A flow-localization parameter that quantifies the flow non-uniform tendency in case of flow softening materials was used to explain the different results in each microstructure. (orig.)

  11. Equalizing effect of the fluctuation in areal irradiance; Chiikinai ni okeru shugo nissha no hendo yokusei koka

    Energy Technology Data Exchange (ETDEWEB)

    Minowa, J; Kurokawa, K [Tokyo University of Agriculture and Technology, Tokyo (Japan); Otani, K; Tsuda, I; Sakuta, K [Electrotechnical Laboratory, Tsukuba (Japan)

    1997-11-25

    Aggravation in electric power quality is concerned because of irregular output power caused by a large number of photovoltaic power generation systems connected with the power grids. However, averaging of the irregularity may be expected in a wide area due to time-based shift in cloud movements. In order to identify this effect, insolation data were measured in terms of planes at multiple points in the city of Tsukuba to discuss the fluctuation equalizing effect. The system is composed of nine instruments to measure insolation plane characteristics, nine terminal station units, and a base station unit. The insolation data express the horizontal plane insolation intensity at a sampling interval of one minute. Insolation fluctuation (standard deviation of insolation fluctuation components) was defined as an index of the insolation fluctuation. Based on the index, an averaging effect when the photovoltaic systems are installed in a number of locations was considered by using statistic estimation. As a result, the averaging effect was obtained even in an area with a radius of several kilometers. In addition, the measurement data revealed that there is an upper limit in the effect depending on the number of system installation. It was also made clear that the data are affected by distances to connect the photovoltaic power generation systems with each other and by climatic conditions. 3 refs., 6 figs.

  12. Not all epidermal growth factor receptor mutations in lung cancer are created equal: Perspectives for individualized treatment strategy.

    Science.gov (United States)

    Kobayashi, Yoshihisa; Mitsudomi, Tetsuya

    2016-09-01

    Somatic mutations in the epidermal growth factor receptor (EGFR) gene are present in approximately 20% (in Caucasians) to 40% (in East Asians) of adenocarcinomas of the lung. Targeted therapy for these lung cancers has been established based on evidence regarding mainly common mutations; that is, exon 19 deletions (Del19) and L858R. EGFR-tyrosine kinase inhibitors (TKI), gefitinib, erlotinib or afatinib showed high objective response rates (ORR) of approximately 60%. Several studies suggested that Del19 might be more sensitive to EGFR-TKI than L858R. On the other hand, it has been difficult to establish evidence for other less common mutations, accounting for 12% of all EGFR mutations, because there are many variants and many studies have excluded patients with these uncommon mutations. However, recent studies revealed that these rare genotypes could be targetable if appropriate TKI are selected. For example, G719X (X denotes A, S, C and so on), Del18, E709K, insertions in exon 19 (Ins19), S768I or L861Q showed moderate sensitivities to gefitinib or erlotinb with ORR of 30%-50%. However, afatinib appeared to be especially effective for these tumors. Although Ins20s (except for insFQEA) have been regarded as resistant mutations, osimertinib may be effective for rare subtypes of them and nazartinib (EGF816) is promising for the majority of them. For the further development of targeted therapy in all EGFR mutations, it is important to precisely detect targetable mutations, to select the most appropriate TKI for each mutation, and to continue investigating in vitro studies and collecting clinical data on even rare mutations. © 2016 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

  13. Effect of nitric acid for equal stabilization and sensitivity of different selenium species in electrothermal atomic absorption spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Sahin, Feyime [Department of Chemistry, Middle East Technical University, 06531 Ankara (Turkey); Volkan, Muervet [Department of Chemistry, Middle East Technical University, 06531 Ankara (Turkey); Ataman, O. Yavuz [Department of Chemistry, Middle East Technical University, 06531 Ankara (Turkey)]. E-mail: ataman@metu.edu.tr

    2005-08-15

    Determination of selenium by electrothermal atomic absorption spectrometry (ETAAS) is complicated by the presence of different species of this analyte. The presence of different oxidation states (-II, IV and VI) may result in different sensitivities obtained for each species rendering impossible the use of a single species for calibration. These species also exhibit different behaviours regarding thermal stabilities; the temperature program must be provided to conform to this problem. Chemical modifiers are commonly used for thermal stabilization of selenium species. In this study, experiments were carried out to demonstrate the effect of nitric acid in the presence of chemical modifiers. Nickel and palladium + magnesium were selected as the most commonly used chemical modifiers. Using both aqueous and human serum solutions it has been demonstrated that although chemical modifiers provide thermal stabilization of species so that higher ashing temperatures can be used, equal sensitivities cannot be achieved unless nitric acid is also present. Selenite, selenate, selenomethionine and selenocystine were used in experiments. When equal sensitivities for all these species are achieved, determination of total selenium by ETAAS can be performed by using a single species as the standard; selenite was used in this study. Precision was 5.0% or better using peak height signals. There was no significant difference in detection limits (3s) when Ni or Pd + Mg(NO{sub 3}){sub 2} was used as chemical modifier; 37 and 35 pg of selenium were found to be the detection limits for Ni and Pd + Mg(NO{sub 3}){sub 2} chemical modifiers, respectively. For chemical modifications, either 5 {mu}g of Ni or 0.5 {mu}g of Pd and 5 {mu}g of Mg(NO{sub 3}){sub 2} were used; final solutions contained 2.5% HNO{sub 3}. In serum analyses, 10 {mu}g of Ni was used in presence of 2.5% HNO{sub 3}.

  14. Medical Need, Equality, and Uncertainty.

    Science.gov (United States)

    Horne, L Chad

    2016-10-01

    Many hold that distributing healthcare according to medical need is a requirement of equality. Most egalitarians believe, however, that people ought to be equal on the whole, by some overall measure of well-being or life-prospects; it would be a massive coincidence if distributing healthcare according to medical need turned out to be an effective way of promoting equality overall. I argue that distributing healthcare according to medical need is important for reducing individuals' uncertainty surrounding their future medical needs. In other words, distributing healthcare according to medical need is a natural feature of healthcare insurance; it is about indemnity, not equality. © 2016 John Wiley & Sons Ltd.

  15. Differential effectiveness of placebo treatments

    DEFF Research Database (Denmark)

    Meissner, Karin; Fässler, Margrit; Rücker, Gerta

    2013-01-01

    IMPORTANCE When analyzing results of randomized clinical trials, the treatment with the greatest specific effect compared with its placebo control is considered to be the most effective one. Although systematic variations of improvements in placebo control groups would have important implications...... relevant sources through February 2012 and contacted the authors to identify randomized clinical trials on the prophylaxis of migraine with an observation period of at least 8 weeks after randomization that compared an experimental treatment with a placebo control group. We calculated pooled random-effects...... and sham surgery are associated with higher responder ratios than oral pharmacological placebos. Clinicians who treat patients with migraine should be aware that a relevant part of the overall effect they observe in practice might be due to nonspecific effects and that the size of such effects might differ...

  16. Effect of Equal Channel Angular Pressing on the Surface Roughness of Solid State Recycled Aluminum Alloy 6061 Chips

    Directory of Open Access Journals (Sweden)

    Adel Taha Abbas

    2017-01-01

    Full Text Available Solid state recycling through hot extrusion is a promising technique to recycle machining chips without remelting. Furthermore, equal channel angular pressing (ECAP technique coupled with the extruded recycled billet is introduced to enhance the mechanical properties of recycled samples. In this paper, the surface roughness of solid state recycled aluminum alloy 6061 turning chips was investigated. Aluminum chips were cold compacted and hot extruded under an extrusion ratio (ER of 5.2 at an extrusion temperature (ET of 425°C. In order to improve the properties of the extruded samples, they were subjected to ECAP up to three passes at room temperature using an ECAP die with a channel die angle (Φ of 90°. Surface roughness (Ra and Rz of the processed recycled billets machined by turning was investigated. Box-Behnken experimental design was used to investigate the effect of three machining parameters (cutting speed, feed rate, and depth of cut on the surface roughness of the machined specimens for four materials conditions, namely, extruded billet and postextrusion ECAP processed billets to one, two, and three passes. Quadratic models were developed to relate the machining parameters to surface roughness, and a multiobjective optimization scheme was conducted to maximize material removal rate while maintaining the roughness below a preset practical value.

  17. Describing treatment effects to patients.

    Science.gov (United States)

    Moxey, Annette; O'Connell, Dianne; McGettigan, Patricia; Henry, David

    2003-11-01

    To examine the impact of different presentations of equivalent information (framing) on treatment decisions faced by patients. A systematic review of the published literature was conducted. English language publications allocating participants to different frames were retrieved using electronic and bibliographic searches. Two reviewers examined each article for inclusion, and assessed methodological quality. Study characteristics were tabulated and where possible, relative risks (RR; 95% confidence intervals) were calculated to estimate intervention effects. Thirty-seven articles, yielding 40 experimental studies, were included. Studies examined treatment (N = 24), immunization (N = 5), or health behavior scenarios (N = 11). Overall, active treatments were preferred when outcomes were described in terms of relative rather than absolute risk reductions or number needed to treat. Surgery was preferred to other treatments when treatment efficacy was presented in a positive frame (survival) rather than a negative frame (mortality) (relative risk [RR] = 1.51, 95% confidence interval [CI], 1.39 to 1.64). Framing effects were less obvious for immunization and health behavior scenarios. Those with little interest in the behavior at baseline were influenced by framing, particularly when information was presented as gains. In studies judged to be of good methodological quality and/or examining actual decisions, the framing effect, although still evident, was less convincing compared to the results of all included studies. Framing effects varied with the type of scenario, responder characteristics, scenario manipulations, and study quality. When describing treatment effects to patients, expressing the information in more than one way may present a balanced view to patients and enable them to make informed decisions.

  18. Fertility effects of cancer treatment.

    Science.gov (United States)

    Marsden, Donald E; Hacker, Neville

    2003-01-01

    Cancer sufferers are a subfertile group, and most treatments have the potential to adversely affect gonadal function. As cancer treatment becomes more effective and survival rates improve there are more cancer survivors in the reproductive age group for whom parenting is an important consideration. This article outlines the effects on fertility of cancer treatments and techniques to minimise the risk of infertility. The overall prospects for younger cancer sufferers to either retain their fertility or have genetic offspring is now better than ever before, due to advances in assisted reproductive technology, the appropriate use of fertility sparing surgery and other techniques to reduce the toxicity of therapy on the reproductive organs. These advances raise new moral and ethical concerns that must be considered before advising cancer sufferers of the options for preserving reproductive capacity.

  19. Are interventions to promote healthy eating equally effective for all? Systematic review of socioeconomic inequalities in impact.

    Science.gov (United States)

    McGill, Rory; Anwar, Elspeth; Orton, Lois; Bromley, Helen; Lloyd-Williams, Ffion; O'Flaherty, Martin; Taylor-Robinson, David; Guzman-Castillo, Maria; Gillespie, Duncan; Moreira, Patricia; Allen, Kirk; Hyseni, Lirije; Calder, Nicola; Petticrew, Mark; White, Martin; Whitehead, Margaret; Capewell, Simon

    2015-05-02

    Interventions to promote healthy eating make a potentially powerful contribution to the primary prevention of non communicable diseases. It is not known whether healthy eating interventions are equally effective among all sections of the population, nor whether they narrow or widen the health gap between rich and poor. We undertook a systematic review of interventions to promote healthy eating to identify whether impacts differ by socioeconomic position (SEP). We searched five bibliographic databases using a pre-piloted search strategy. Retrieved articles were screened independently by two reviewers. Healthier diets were defined as the reduced intake of salt, sugar, trans-fats, saturated fat, total fat, or total calories, or increased consumption of fruit, vegetables and wholegrain. Studies were only included if quantitative results were presented by a measure of SEP. Extracted data were categorised with a modified version of the "4Ps" marketing mix, expanded to 6 "Ps": "Price, Place, Product, Prescriptive, Promotion, and Person". Our search identified 31,887 articles. Following screening, 36 studies were included: 18 "Price" interventions, 6 "Place" interventions, 1 "Product" intervention, zero "Prescriptive" interventions, 4 "Promotion" interventions, and 18 "Person" interventions. "Price" interventions were most effective in groups with lower SEP, and may therefore appear likely to reduce inequalities. All interventions that combined taxes and subsidies consistently decreased inequalities. Conversely, interventions categorised as "Person" had a greater impact with increasing SEP, and may therefore appear likely to reduce inequalities. All four dietary counselling interventions appear likely to widen inequalities. We did not find any "Prescriptive" interventions and only one "Product" intervention that presented differential results and had no impact by SEP. More "Place" interventions were identified and none of these interventions were judged as likely to widen

  20. Applying the Equal Pay Act to State and Local Governments: The Effect of National League of Cities v. Usery

    Science.gov (United States)

    University of Pennsylvania Law Review, 1977

    1977-01-01

    The constitutionality of the Equal Pay Act is examined as an exercise of Congress' power under the enforcement clause of the fourteenth amendment and it is concluded that application of the Act to public employees in both traditional and nontraditional governmental functions is a constitutional exercise of that congressional power. (LBH)

  1. Electricity's effect on gender equality in rural Zanzibar, Tanzania : case study for Gender and Energy World Development Report Background Paper

    NARCIS (Netherlands)

    Winther, Tanja

    2012-01-01

    This anthropological case study on the introduction of electricity in rural Zanzibar around 1990 discusses to what extent and how women became empowered in the process. What factors contributed to increased gender equality during the uptake of electricity and related appliances – and what were the

  2. Effect of Annealing on the Pitting Corrosion Resistance of Anodized Aluminum-Magnesium Alloy Processed by Equal Channel Angular Pressing

    Energy Technology Data Exchange (ETDEWEB)

    Son, In Joon; Nakano, Hiroaki; Oue, Satoshi; Fukushima, Hisaaki; Horita, Zenji [Kyushu University, Fukuoka (Japan); Kobayashi, Shigeo [Kyushu Sangyo University, Fukuoka (Japan)

    2007-12-15

    The effect of annealing on the pitting corrosion resistance of anodized Al-Mg alloy (AA5052) processed by equal-channel angular pressing (ECAP) was investigated by electrochemical techniques in a solution containing 0.2 mol/L of AlCl{sub 3} and also by surface analysis. The Al-Mg alloy was annealed at a fixed temperature between 473 and 573 K for 120 min in air after ECAP. Anodizing was conducted for 40 min at 100-400 A/m{sup 2} at 293 K in a solution containing 1.53 mol/L of H{sub 2}SO{sub 4} and 0.0185 mol/L of Al{sub 2}(SO{sub 4}){sub 3}. The internal stress generated in anodic oxide films during anodization was measured with a strain gauge to clarify the effect of ECAP on the pitting corrosion resistance of anodized Al-Mg alloy. The time required to initiate the pitting corrosion of anodized Al-Mg alloy was shorter in samples subjected to ECAP, indicating that ECAP decreased the pitting corrosion resistance. however, the pitting corrosion resistance was greatly improved by annealing after ECAP. The time required to initiate pitting corrosion increased with increasing annealing temperature. The strain gauge attached to Al-Mg alloy revealed that the internal stress present in the anodic oxide films was compressive stress, and that the stress was larger with ECAP than without. The compressive internal stress gradually decreased with increasing annealing temperature. Scanning electron microscopy showed that cracks occurred in the anodic oxide film on Al-Mg alloy during initial corrosion and that the cracks were larger with ECAP than without. The ECAP process of severe plastic deformation produces large internal stresses in the Al-Mg alloy: the stresses remain in the anodic oxide films, increasing the likelihood of cracks. it is assumed that the pitting corrosion is promoted by these cracks as a result of the higher internal stress resulting from ECAP. The improvement in the pitting corrosion resistance of anodized AlMg alloy as a result of annealing appears to be

  3. Effect of Annealing on the Pitting Corrosion Resistance of Anodized Aluminum-Magnesium Alloy Processed by Equal Channel Angular Pressing

    International Nuclear Information System (INIS)

    Son, In Joon; Nakano, Hiroaki; Oue, Satoshi; Fukushima, Hisaaki; Horita, Zenji; Kobayashi, Shigeo

    2007-01-01

    The effect of annealing on the pitting corrosion resistance of anodized Al-Mg alloy (AA5052) processed by equal-channel angular pressing (ECAP) was investigated by electrochemical techniques in a solution containing 0.2 mol/L of AlCl 3 and also by surface analysis. The Al-Mg alloy was annealed at a fixed temperature between 473 and 573 K for 120 min in air after ECAP. Anodizing was conducted for 40 min at 100-400 A/m 2 at 293 K in a solution containing 1.53 mol/L of H 2 SO 4 and 0.0185 mol/L of Al 2 (SO 4 ) 3 . The internal stress generated in anodic oxide films during anodization was measured with a strain gauge to clarify the effect of ECAP on the pitting corrosion resistance of anodized Al-Mg alloy. The time required to initiate the pitting corrosion of anodized Al-Mg alloy was shorter in samples subjected to ECAP, indicating that ECAP decreased the pitting corrosion resistance. however, the pitting corrosion resistance was greatly improved by annealing after ECAP. The time required to initiate pitting corrosion increased with increasing annealing temperature. The strain gauge attached to Al-Mg alloy revealed that the internal stress present in the anodic oxide films was compressive stress, and that the stress was larger with ECAP than without. The compressive internal stress gradually decreased with increasing annealing temperature. Scanning electron microscopy showed that cracks occurred in the anodic oxide film on Al-Mg alloy during initial corrosion and that the cracks were larger with ECAP than without. The ECAP process of severe plastic deformation produces large internal stresses in the Al-Mg alloy: the stresses remain in the anodic oxide films, increasing the likelihood of cracks. it is assumed that the pitting corrosion is promoted by these cracks as a result of the higher internal stress resulting from ECAP. The improvement in the pitting corrosion resistance of anodized AlMg alloy as a result of annealing appears to be attributable to a decrease in

  4. Effects of exposure equalization on image signal-to-noise ratios in digital mammography: A simulation study with an anthropomorphic breast phantom

    Energy Technology Data Exchange (ETDEWEB)

    Liu Xinming; Lai Chaojen; Whitman, Gary J.; Geiser, William R.; Shen Youtao; Yi Ying; Shaw, Chris C. [Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, Texas 77030-4009 (United States); Department of Diagnostic Radiology, University of Texas MD Anderson Cancer Center, Houston, Texas 77030-4009 (United States); Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, Texas 77030-4009 (United States)

    2011-12-15

    Purpose: The scan equalization digital mammography (SEDM) technique combines slot scanning and exposure equalization to improve low-contrast performance of digital mammography in dense tissue areas. In this study, full-field digital mammography (FFDM) images of an anthropomorphic breast phantom acquired with an anti-scatter grid at various exposure levels were superimposed to simulate SEDM images and investigate the improvement of low-contrast performance as quantified by primary signal-to-noise ratios (PSNRs). Methods: We imaged an anthropomorphic breast phantom (Gammex 169 ''Rachel,'' Gammex RMI, Middleton, WI) at various exposure levels using a FFDM system (Senographe 2000D, GE Medical Systems, Milwaukee, WI). The exposure equalization factors were computed based on a standard FFDM image acquired in the automatic exposure control (AEC) mode. The equalized image was simulated and constructed by superimposing a selected set of FFDM images acquired at 2, 1, 1/2, 1/4, 1/8, 1/16, and 1/32 times of exposure levels to the standard AEC timed technique (125 mAs) using the equalization factors computed for each region. Finally, the equalized image was renormalized regionally with the exposure equalization factors to result in an appearance similar to that with standard digital mammography. Two sets of FFDM images were acquired to allow for two identically, but independently, formed equalized images to be subtracted from each other to estimate the noise levels. Similarly, two identically but independently acquired standard FFDM images were subtracted to estimate the noise levels. Corrections were applied to remove the excess system noise accumulated during image superimposition in forming the equalized image. PSNRs over the compressed area of breast phantom were computed and used to quantitatively study the effects of exposure equalization on low-contrast performance in digital mammography. Results: We found that the highest achievable PSNR improvement

  5. Effects of exposure equalization on image signal-to-noise ratios in digital mammography: A simulation study with an anthropomorphic breast phantom

    International Nuclear Information System (INIS)

    Liu Xinming; Lai Chaojen; Whitman, Gary J.; Geiser, William R.; Shen Youtao; Yi Ying; Shaw, Chris C.

    2011-01-01

    Purpose: The scan equalization digital mammography (SEDM) technique combines slot scanning and exposure equalization to improve low-contrast performance of digital mammography in dense tissue areas. In this study, full-field digital mammography (FFDM) images of an anthropomorphic breast phantom acquired with an anti-scatter grid at various exposure levels were superimposed to simulate SEDM images and investigate the improvement of low-contrast performance as quantified by primary signal-to-noise ratios (PSNRs). Methods: We imaged an anthropomorphic breast phantom (Gammex 169 ''Rachel,'' Gammex RMI, Middleton, WI) at various exposure levels using a FFDM system (Senographe 2000D, GE Medical Systems, Milwaukee, WI). The exposure equalization factors were computed based on a standard FFDM image acquired in the automatic exposure control (AEC) mode. The equalized image was simulated and constructed by superimposing a selected set of FFDM images acquired at 2, 1, 1/2, 1/4, 1/8, 1/16, and 1/32 times of exposure levels to the standard AEC timed technique (125 mAs) using the equalization factors computed for each region. Finally, the equalized image was renormalized regionally with the exposure equalization factors to result in an appearance similar to that with standard digital mammography. Two sets of FFDM images were acquired to allow for two identically, but independently, formed equalized images to be subtracted from each other to estimate the noise levels. Similarly, two identically but independently acquired standard FFDM images were subtracted to estimate the noise levels. Corrections were applied to remove the excess system noise accumulated during image superimposition in forming the equalized image. PSNRs over the compressed area of breast phantom were computed and used to quantitatively study the effects of exposure equalization on low-contrast performance in digital mammography. Results: We found that the highest achievable PSNR improvement factor was 1.89 for

  6. Some Equalities Are More Equal Than Others: Quality Equality Emerges Later Than Numerical Equality.

    Science.gov (United States)

    Sheskin, Mark; Nadal, Amber; Croom, Adam; Mayer, Tanya; Nissel, Jenny; Bloom, Paul

    2016-09-01

    By age 6, children typically share an equal number of resources between themselves and others. However, fairness involves not merely that each person receive an equal number of resources ("numerical equality") but also that each person receive equal quality resources ("quality equality"). In Study 1, children (N = 87, 3-10 years) typically split four resources "two each" by age 6, but typically monopolized the better two resources until age 10. In Study 2, a new group of 6- to 8-year-olds (N = 32) allocated resources to third parties according to quality equality, indicating that children in this age group understand that fairness requires both types of equality. © 2016 The Authors. Child Development © 2016 Society for Research in Child Development, Inc.

  7. Particle-number fluctuations and neutron-proton pairing effects on proton and neutron radii of even-even N Almost-Equal-To Z nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Douici, M.; Allal, N. H.; Fellah, M.; Benhamouda, N.; Oudih, M. R. [Laboratoire de Physique Theorique, Faculte de Physique, USTHB BP 32 El-Alia, 16111 Bab-Ezzouar, Alger (Algeria) and Institut des Sciences et Technologie, Centre Universitaire de Khemis Miliana, Route de Theniet-El-Had, 44225 Khemis-Milia (Algeria); Laboratoire de Physique Theorique, Faculte de Physique, USTHB BP 32 El-Alia, 16111 Bab-Ezzouar, Alger (Algeria) and Centre de Recherche Nucleaire d' Alger, COMENA, BP399 Alger-Gare, Alger (Algeria); Laboratoire de Physique Theorique, Faculte de Physique, USTHB BP 32 El-Alia, 16111 Bab-Ezzouar, Alger (Algeria)

    2012-10-20

    The particle-number fluctuation effect on the root-mean-square (rms) proton and neutron radii of even-even N Almost-Equal-To Z nuclei is studied in the isovector neutron-proton (np) pairing case using an exact particle-number projection method and the Woods-Saxon model.

  8. Equality of Opportunity and Equality of Outcome

    Science.gov (United States)

    Kodelja, Zdenko

    2016-01-01

    The report on the findings of extensive empirical research on equality of educational opportunities carried out in the United States on a very large sample of public schools by Coleman and his colleagues has had a major impact on education policy and has given rise to a large amount of research and various interpretations. However, as some…

  9. Ethical Perspectives of Equal Opportunities

    Directory of Open Access Journals (Sweden)

    Traian PALADE

    2016-07-01

    Full Text Available This paper focuses on the analysis of the fair equality of the concept of opportunity from the perspective of the moral and reasonable justifications brought to support positive discrimination. Although contemporary democratic societies guarantee the absence of discrimination by securing the formal equality of opportunity, this seems to be insufficient to balance opportunities. The Rawlsian model has gained ground, by advancing a redistribution of the resources to support the disadvantaged ones, which is implemented through special measures. The compulsory quotas for admission to higher education or public institutions, addressed to some disadvantaged groups, are one of the effective means of implementing fairness. As this system has shattered the principle of reward judging by one‟s merits, and ending up as a form of inverse discrimination of the majority groups, it is necessary that we analyse the arguments and the boomerang effects of the special measures. The undertaking proposed by the present paper is structured around highlighting the ethical aspects, as well as the consequences resulting from the arguments in favour of positive discrimination. Do we have the moral obligation to make up for the past inequalities suffered by some groups? Does preferential treatment really ensure the genuine integration of such groups? Do special measures contribute in creating social justice? Without the claim of having responded definitively and exhaustively to these questions, this paper attempts to emphasise the ethical dilemma that raises when special measures favour one group or another, when a group is protected judging by only one criterion, or when only an implementation area is selected.

  10. Equality versus equity bases pay systems and their effects on rational altruism motivation in teams: wicked masked altruism

    OpenAIRE

    Javier García Bernal; Marisa Ramírez Alesón

    2007-01-01

    This paper analyses the design of optimal incentives in teams both with and without rational altruism. The main contribution of the paper is to study the influence of the incentive function on the altruism parameter chosen by team members. We find that optimal incentive is independent of the presence of rational altruism. Secondly, we compare the welfare loss of equal sharing rules versus second best optimal sharing rules (based on equity). Finally, we distinguish between two sources of ratio...

  11. Immunological and virological response to antiretroviral treatment in migrant and native men and women in Western Europe; is benefit equal for all?

    Science.gov (United States)

    2018-01-01

    The aim of the study was to evaluate differences in immunovirological response to combination antiretroviral therapy (cART) in migrant and native men and women within a European collaboration of HIV cohorts Collaboration of Observational HIV Epidemiological Research in Europ (COHERE) in EuroCoord, 2004-2013. Migrants were defined as those with geographical origin (GO) different from the reporting country and were grouped as originating from Western Europe and Western Countries (WEWC), Eastern Europe (EE), North Africa and the Middle East (NAME), sub-Saharan Africa (SSA), Latin America (LA), Caribbean (CRB) and Asia/Oceania (ASIA/OCE). Native (NAT) individuals were defined as those originating from the reporting country. CD4 cell counts were modelled using piecewise linear mixed-effects models with two slopes, whereas models to estimate subdistribution hazard ratios (sHRs) were used for time to virological response (VR) (i.e. time from cART initiation to the first of two successive HIV RNA measurements response to cART in Western Europe varies by GO and sex of patients. ART benefits are not equal for all, underlining the point that efforts need to prioritize those most in need. © 2017 British HIV Association.

  12. Gender equality and meritocracy

    OpenAIRE

    Powell, Stina

    2016-01-01

    This thesis examines how gender equality measures and discourses are reconciled with notions of merit in academia. Gender equality is often defined as equal rights for women and men and has become a widely accepted political goal and vision. Meritocratic principles build on the assumption that everyone, regardless of gender, class, race and sexuality, has the same opportunities to advance provided they are sufficiently hardworking and intelligent. Meritocratic principles thus build on the ass...

  13. Dis-Equality: Exploring the Juxtaposition of Disability and Equality

    Directory of Open Access Journals (Sweden)

    Bronagh Byrne

    2018-03-01

    Full Text Available The (inequality issues facing disabled people are extensive and long-enduring. The way(s in which equality is conceptualised has important consequences for understandings of disability. The ambiguity of what I call dis-equality theory is two-fold; the apparent failure of mainstream equality theorising in, firstly, embracing disability concepts at all, and secondly, in fully incorporating the logistics of disability, particularly in relation to the social construction of such. Practices of institutional and more complex forms of discrimination are part of those deeper structures of domination and oppression which maintain disabled people in positions of disadvantage. Everyday practices, in the ‘ordinary order of things’ (Bourdieu, 2000, continue to be misrecognised as natural and taken for granted. This article critically explores the complexity of dis-equality theorising utilising a Bourdieusian lens which explicitly incorporates complex and subtle forms of discrimination, and by examining the UN Convention on the Rights of Persons with Disabilities’ approach to equality. I argue that the way forward for dis-equality theorising in today’s rights based era must be one that considers the nuances of the ‘rules of the game’ (Young, 1990 if it is to be effective in challenging the inequalities to which disabled people have long been subject.

  14. Asynchronous LMS adaptive equalization

    NARCIS (Netherlands)

    Bergmans, J.W.M.; Lin, M.Y.; Modrie, D.; Otte, R.

    2005-01-01

    Digital data receivers often operate at a fixed sampling rate 1/Ts that is asynchronous to the baud rate 1/T. A digital equalizer that processes the incoming signal will also operate in the asynchronous clock domain. Existing adaptation techniques for this equalizer involve an error sequence ek that

  15. Is Equality Fair?

    Directory of Open Access Journals (Sweden)

    Arthur Tarasov

    2015-11-01

    Full Text Available This paper attempts to answer the question whether people consider decisions that lead to equal outcomes fair. I find that this is not always the case. In an experiment where subjects are given equal opportunities to choose how to divide money between each other in a two-player game, any strategy is perceived to be fair more than half the time, including the profit-maximizing strategy. The equal divisions that lead to equal outcomes are sometimes considered unfair by both players. Moreover, players frequently punished the others, whose decisions led to equal outcomes. I hypothesize that such punishments occur because people have different conceptions of what a fair outcome and fair punishment are

  16. Loudspeaker Equalization with Post-Processing

    Directory of Open Access Journals (Sweden)

    Ser Wee

    2002-01-01

    Full Text Available Loudspeaker equalization is an essential technique in audio system design. A well-known equalization scheme is based on the deconvolution of the desired equalized response with the measured impulse response of the loudspeaker. In this paper, a post-processing scheme is combined with the deconvolution-based algorithm to provide a better equalization effect. Computer simulation results are given to demonstrate the significant improvement that can be achieved using this method.

  17. Preventive and Regenerative Foam Rolling are Equally Effective in Reducing Fatigue-Related Impairments of Muscle Function following Exercise

    Directory of Open Access Journals (Sweden)

    Johannes Fleckenstein, Jan Wilke, Lutz Vogt, Winfried Banzer

    2017-12-01

    Full Text Available Objectives of the study were to compare the effects of a single bout of preventive or regenerative foam rolling (FR on exercise-induced neuromuscular exhaustion. Single-centre randomised-controlled study was designed. Forty-five healthy adults (22 female; 25±2 yrs were allocated to three groups: 1 FR of the lower limb muscles prior to induction of fatigue, 2 FR after induction of fatigue, 3 no-treatment control. Neuromuscular exhaustion was provoked using a standardized and validated functional agility short-term fatigue protocol. Main outcome measure was the maximal isometric voluntary force of the knee extensors (MIVF. Secondary outcomes included pain and reactive strength (RSI. Preventive (-16% and regenerative FR (-12% resulted in a decreased loss in MIVF compared to control (-21%; p 0.8, p < 0.1. Differences over time (p < 0.001 between groups regarding pain and RSI did not turn out to be clinically meaningful. A single bout of foam rolling reduces neuromuscular exhaustion with reference to maximal force production. Regenerative rather than preventive foam rolling seems sufficient to prevent further fatigue.

  18. The Europeanisation of gender equality

    DEFF Research Database (Denmark)

    Martinsen, Dorte Sindbjerg

    2007-01-01

    The paper examines the extent to which member states control the impact of European Union (EU) policies. It does so through an historical study of what is considered to be the ‘least likely case’ – the Europeanization of Danish gender equality. The analytical findings identify various and diverse...... effects of European integration over time on national policy, politics and law. Historically, the EU has had a major role in furthering and putting into effect equality rights – even in the ‘least likely’ case of Denmark. From a theoretical perspective, the paper argues that the study of Europeanization...

  19. The Treatment Effectiveness Assessment (TEA

    Directory of Open Access Journals (Sweden)

    Ling W

    2013-09-01

    Full Text Available Walter Ling,1 David Farabee,1 Dagmar Liepa,2 Li-Tzy Wu3 1Integrated Substance Abuse Programs, University of California, Los Angeles, CA, 2Valley Care Medical Center, Panorama City, CA, 3Department of Psychiatry and Behavioral Sciences, School of Medicine, Duke University Medical Center, Durham, NC, USA We have been surprised and gratified by the readers’ responses to our article, The Treatment Effectiveness Assessment (TEA: an efficient, patient-centered instrument for evaluating progress in recovery from addiction, which was published in December 2012.1 In the six months since that time, we have received numerous questions and observations about the article, and about the TEA instrument. Respondents were clinicians: physicians, counselors, therapists, nurses; as well as administrators and policy makers.  View original paper by Ling W, Farabee D, Liepa D, Wu LT. 

  20. Investigation of the equality constraint effect on the reduction of the rotational ambiguity in three-component system using a novel grid search method.

    Science.gov (United States)

    Beyramysoltan, Samira; Rajkó, Róbert; Abdollahi, Hamid

    2013-08-12

    The obtained results by soft modeling multivariate curve resolution methods often are not unique and are questionable because of rotational ambiguity. It means a range of feasible solutions equally fit experimental data and fulfill the constraints. Regarding to chemometric literature, a survey of useful constraints for the reduction of the rotational ambiguity is a big challenge for chemometrician. It is worth to study the effects of applying constraints on the reduction of rotational ambiguity, since it can help us to choose the useful constraints in order to impose in multivariate curve resolution methods for analyzing data sets. In this work, we have investigated the effect of equality constraint on decreasing of the rotational ambiguity. For calculation of all feasible solutions corresponding with known spectrum, a novel systematic grid search method based on Species-based Particle Swarm Optimization is proposed in a three-component system. Copyright © 2013 Elsevier B.V. All rights reserved.

  1. Effect of equal-channel angular pressing and aging on the microstructure and mechanical properties of an Al-Cu-Mg-Si alloy

    Science.gov (United States)

    Gazizov, M. R.; Dubina, A. V.; Zhemchuzhnikova, D. A.; Kaibyshev, R. O.

    2015-07-01

    The effect of intermediate equal-channel angular pressing (ECAP) and final aging at 170°C on the mechanical properties and microstructure of aluminum alloy belonging to Al-Cu-Mg-Si system stress with a Cu/Mg ratio (AA2014) is considered. After quenching and aging (treatment T6), the yield stress (σ0.2) and ultimate tensile strength (σu) are ˜415 and ˜450 MPa, respectively; the elongation to fracture (δ) is 4.2%. The precipitation strengthening is reached due to the precipitation of θ″-, θ'-, β″-, and Q'/ C-phase particles. After intermediate ECAP and subsequent aging for 0.5 h, σ0.2 and σu increase to 470 and 535 MPa, respectively; δ increases to ˜9.5%. The plastic deformation leads to the formation of a microstructure that consists of deformation bands characterized by a high density of dislocations. During aging for 0.5 h, the partial decomposition of supersaturated solid solution and formation of segregations within grains and at dislocations and precipitation of the Guinier-Preston zones and β″ phase also occur; all of this ensure the maximum increase in the strength of the AA2014 alloy. As the aging time increases to 8 h, the slight decrease in both σ0.2 and σu to 465 and 515 MPa and δ to ˜6% takes place. It has been shown that the intermediate ECAP does not affect the sequence of the precipitation of main strengthening θ″ and θ' phases during aging. However, in this case, the volume fraction of strengthening particles decreases significantly and their dispersivity increases.

  2. Coping with Cosmetic Effects of Cancer Treatment

    Science.gov (United States)

    ... Search English Español Coping With Cosmetic Effects of Cancer Treatment KidsHealth / For Parents / Coping With Cosmetic Effects of Cancer Treatment What's in this article? Hair Loss Skin Problems ...

  3. Trust, Welfare States and Income Equality

    DEFF Research Database (Denmark)

    Bergh, Andreas; Bjørnskov, Christian

    2014-01-01

    The cross-country correlation between social trust and income equality is well documented, but few studies examine the direction of causality. We show theoretically that by facilitating cooperation, trust may lead to more equal outcomes, while the feedback from inequality to trust is ambiguous....... Using a structural equation model estimated on a large country sample, we find that trust has a positive effect on both market and net income equality. Larger welfare states lead to higher net equality but neither net income equality nor welfare state size seems to have a causal effect on trust. We...

  4. TAXATION. FAIRNESS. EQUALITY

    Directory of Open Access Journals (Sweden)

    Morar Ioan Dan

    2014-12-01

    Full Text Available The issue of taxation is a phenomenon long past barriers fiscal regulations and procedures, as in the contemporary period is a phenomenon with multiple implications of economic, social and political. Tax procedures also were upgraded and complicated that not only specialists but also taxpayers need the jurisdictional knowledge, informatics and especially in the economic field. Dealing over the jurisdictional and procedural measure, it seems that the other side of the relationship between tax authorities and taxpayers, the economic and psycho-behavioral was neglected. Tax authorities as part of the administrative system, whose main objective attracting tax revenues to the Exchequer in terms of data legislation, legislation that reflects the vision of the governments policy in operation. One must ask if the official fiscal policies, take into account the coordinates of the report psychobehavioral tax? The answer to this question and some comments to address this issue, this paper covered together. The tax will not ever paid with pleasure, but it is known that fiscal equity confers a degree of acceptance by payers of the tax burden. Modern fiscal policies are marked by complicated structure of tax systems, more sophisticated procedures and rush image of politicians that do not retain as little detriment to promote populism reality. Another problem is the invasion of of social security, namely the objective is also looking to be promoted on account of fiscal policy without taking into account the fact that the two policies, the fiscal and social security are still their primary objective. The combination of the two types of , the purely fiscal and social, administrative approach is undoubtedly affected, and the effectiveness of the two policies may be affected taxpayers reactions is recognized in the literature are controversial. Taxpayers are vexed not only the size of the tax burden but also its structure, especially the way the official division

  5. Valuing Equal Protection in Aviation Security Screening.

    Science.gov (United States)

    Nguyen, Kenneth D; Rosoff, Heather; John, Richard S

    2017-12-01

    The growing number of anti-terrorism policies has elevated public concerns about discrimination. Within the context of airport security screening, the current study examines how American travelers value the principle of equal protection by quantifying the "equity premium" that they are willing to sacrifice to avoid screening procedures that result in differential treatments. In addition, we applied the notion of procedural justice to explore the effect of alternative selective screening procedures on the value of equal protection. Two-hundred and twenty-two respondents were randomly assigned to one of three selective screening procedures: (1) randomly, (2) using behavioral indicators, or (3) based on demographic characteristics. They were asked to choose between airlines using either an equal or a discriminatory screening procedure. While the former requires all passengers to be screened in the same manner, the latter mandates all passengers undergo a quick primary screening and, in addition, some passengers are selected for a secondary screening based on a predetermined selection criterion. Equity premiums were quantified in terms of monetary cost, wait time, convenience, and safety compromise. Results show that equity premiums varied greatly across respondents, with many indicating little willingness to sacrifice to avoid inequitable screening, and a smaller minority willing to sacrifice anything to avoid the discriminatory screening. The selective screening manipulation was effective in that equity premiums were greater under selection by demographic characteristics compared to the other two procedures. © 2017 Society for Risk Analysis.

  6. Effect of equal channel angular pressing on the microstructure and mechanical properties of Al-10Zn-2Mg alloy

    Science.gov (United States)

    Manjunath, G. K.; Kumar, G. V. Preetham; Bhat, K. Udaya

    2018-04-01

    The current investigation is focused on evaluating the mechanical properties and the microstructure of cast Al-10Zn-2Mg alloy processed through equal channel angular pressing (ECAP). The ECAP processing was attempted at minimum possible processing temperature. Microstructural characterization was carried out in optical microscopy, scanning electron microscopy, transmission electron microscopy and X-ray diffraction analysis. Hardness measurement and tensile tests were employed to estimate the mechanical properties. Experimental results showed that, ECAP processing leads to noticeable grain refinement in the alloy. Reasonable amount of dislocations were observed in the ECAP processed material. After ECAP processing, precipitates nucleation in the material was detected in the XRD analysis. ECAP leads to considerable enhancement in the mechanical properties of the material. After ECAP processing, microhardness of the material is increased from 144 Hv to 216 Hv. Also, after ECAP processing the UTS of the material is increased from 140 MPa to 302 MPa. The increase in the mechanical properties of the alloy after ECAP processing is due to the dislocation strengthening and grain refinement strengthening. Finally, fracture surface morphology of the tensile test samples also studied.

  7. The uneasy marriage between Law and Equality

    NARCIS (Netherlands)

    Westerman, Pauline C.

    2015-01-01

    There are two ways in which the social ideal of equality has found expression in the law: in the principle of equal treatment and in the principle of non-discrimination. In this article the meaning of these two legal principles is analysed, in order to answer the question to what extent they can be

  8. Effects of three warm-up regimens of equal distance on VO2 kinetics during supramaximal exercise in Thoroughbred horses.

    Science.gov (United States)

    Mukai, K; Hiraga, A; Takahashi, T; Ohmura, H; Jones, J H

    2010-11-01

    Several studies have indicated that even low-intensity warm-up increases O(2) transport kinetics and that high-intensity warm-up may not be needed in horses. However, conventional warm-up exercise for Thoroughbred races is more intense than those utilised in previous studies of equine warm-up responses. To test the hypothesis that warm-up exercise at different intensities alters the kinetics and total contribution of aerobic power to total metabolic power in subsequent supramaximal (sprint) exercise in Thoroughbred horses. Nine well-trained Thoroughbreds ran until fatigue at 115% of maximal oxygen consumption (VO2max) 10 min after warming-up under each of 3 protocols of equal running distance: 400 s at 30% VO2max (LoWU), 200 s at 60% VO2max (MoWU) and 120 s at 100% VO2max (HiWU). Variables measured during exercise were rates of O(2) and CO(2) consumption/production (VO2,VO2), respiratory exchange ratio (RER), heart rate, blood lactate concentration and accumulation rate and blood gas variables. VO2 was significantly higher in HiWU than in LoWU at the onset of the sprint exercise and HR was significantly higher in HiWU than in LoWU throughout the sprint. Accumulation of blood lactate, RER, P(a)CO(2) and PvCO2 in the first 60 s were significantly lower in HiWU than in LoWU and MoWU. There were no significant differences in stroke volume, run time or arterial-mixed venous O(2) concentration. These results suggest HiWU accelerates kinetics and reduces reliance on net anaerobic power compared with LoWU at the onset of the subsequent sprint. © 2010 EVJ Ltd.

  9. Low-intensity blue-enriched white light (750 lux) and standard bright light (10 000 lux) are equally effective in treating SAD. A randomized controlled study

    NARCIS (Netherlands)

    Meesters, Ybe; Dekker, Vera; Schlangen, Luc J. M.; Bos, Elske H.; Ruiter, Martine J.

    2011-01-01

    Background: Photoreceptor cells containing melanopsin play a role in the phase-shifting effects of short-wavelength light. In a previous study, we compared the standard light treatment (SLT) of SAD with treatment using short-wavelength blue-enriched white light (BLT). Both treatments used the same

  10. The Uneasy Marriage between Law and Equality

    Directory of Open Access Journals (Sweden)

    Pauline C. Westerman

    2015-02-01

    Full Text Available There are two ways in which the social ideal of equality has found expression in the law: in the principle of equal treatment and in the principle of non-discrimination. In this article the meaning of these two legal principles is analysed, in order to answer the question to what extent they can be said to contribute to equality in the sense of an equal distribution of collective resources. It is argued that whereas the first just requires decision-making to be rule-based, the second principle demands that rules should be based on sound categorical distinctions. Neither of the two can, however, sensibly be linked to equality as equal distribution. The article concludes that the only way to establish such a link is by adding to the principle of non-discrimination “financial resources” as a suspect ground.

  11. Coaxial transmission line - Equalization

    International Nuclear Information System (INIS)

    Bonnerue, J.L.; Fremont, Jacques; Haubtmann, Jack; Pillon, Gerard.

    1981-09-01

    The transmission of electrical signal through a coaxial line is not perfect and signal distortions are increased as much as the frequency spectrum is extended. We have designed and achieved passive filters (named equalizers) with transfer functions which are inverse of coaxial transfer functions. Doing so our attempt is to avoid definitive loss of information in the recorded data. The main feature of our equalization method lies in the fact it could be either an electrical or a numerical correction or both of them. Some examples in the use of this technique are also proposed [fr

  12. Gender equality revisited:

    DEFF Research Database (Denmark)

    Rostgaard, Tine; B. Eydal, G.

    2011-01-01

    The Nordic childcare policy model is often reviewed and even recommended internationally for its contribution to gender equality, high female labour force participation and, perhaps more indirectly, to a high fertility rate. Nordic childcare services and parental leave schemes have thus been...... portrayed in the literature as policies which have managed to facilitate a work–family model of dual earners and dual carers. However, the recent introduction of cash-for-care schemes seems to go against the Nordic dual earner/dual carer model and ideals of gender equality, in supporting parental (maternal...

  13. Beyond the treatment effect: Evaluating the effects of patient preferences in randomised trials.

    Science.gov (United States)

    Walter, S D; Turner, R; Macaskill, P; McCaffery, K J; Irwig, L

    2017-02-01

    The treatments under comparison in a randomised trial should ideally have equal value and acceptability - a position of equipoise - to study participants. However, it is unlikely that true equipoise exists in practice, because at least some participants may have preferences for one treatment or the other, for a variety of reasons. These preferences may be related to study outcomes, and hence affect the estimation of the treatment effect. Furthermore, the effects of preferences can sometimes be substantial, and may even be larger than the direct effect of treatment. Preference effects are of interest in their own right, but they cannot be assessed in the standard parallel group design for a randomised trial. In this paper, we describe a model to represent the impact of preferences on trial outcomes, in addition to the usual treatment effect. In particular, we describe how outcomes might differ between participants who would choose one treatment or the other, if they were free to do so. Additionally, we investigate the difference in outcomes depending on whether or not a participant receives his or her preferred treatment, which we characterise through a so-called preference effect. We then discuss several study designs that have been proposed to measure and exploit data on preferences, and which constitute alternatives to the conventional parallel group design. Based on the model framework, we determine which of the various preference effects can or cannot be estimated with each design. We also illustrate these ideas with some examples of preference designs from the literature.

  14. Entrepreneur for Equality

    DEFF Research Database (Denmark)

    Duncan, Russell

    Focuses on the first Republican Governor of the state of Georgia during the period of race adjustment and national reconstruction after the American Civil War. Bullock led the way to business connections in creating a New South, but he was best known for his steadfast efforts at human equality fo...

  15. Equal Educational Opportunity?

    Science.gov (United States)

    Morris, Lorenzo

    1980-01-01

    Holds that the "Bakke" decision simply reaffirmed an insufficient commitment to equal opportunities for Blacks in higher education. Reviews several studies, including research conducted at the Institute for the Study of Educational Policy (ISEP) that has focused on the social and economic context of educational discrimination. (GC)

  16. Fight For Equality

    Science.gov (United States)

    Mink, Patsy T.

    1973-01-01

    In this presentation to the annual conventions of the NAWDAC and the ACPA (Cleveland 1973) the author, a Congresswoman from Hawaii, deplores the practice of some counselors of directing women students into traditional women's courses. She urges college counselors and personnel workers to join in the struggle to achieve equal educational and…

  17. Equal Rights Monitor

    NARCIS (Netherlands)

    Saskia Keuzenkamp; Ko Oudhof

    2000-01-01

    Original title: Emancipatiemonitor 2000. How is the emancipation process of women in the Netherlands progressing? What has been achieved? Have women already achieved equality, and have men accepted the sharing of power and responsibility? Was the emancipation process mainly a phenomenon of

  18. Not All Promotions are Made Equal: From the Effects of a Price War to Cross-chain Cannibalization

    NARCIS (Netherlands)

    F. Sotgiu (Francesca)

    2010-01-01

    textabstractDespite the huge amount of money allocated every year to sales promotions, brand managers still do not know how often and in what circumstances promotions are truly effective. This dissertation proposes an approach that allows managers to assess the impact of individual promotion events

  19. Annealing behavior and shape memory effect in NiTi alloy processed by equal-channel angular pressing at room temperature

    International Nuclear Information System (INIS)

    Shahmir, Hamed; Nili-Ahmadabadi, Mahmoud; Wang, Chuan Ting; Jung, Jai Myun; Kim, Hyoung Seop; Langdon, Terence G.

    2015-01-01

    A martensitic NiTi shape memory alloy was processed successfully by equal-channel angular pressing (ECAP) for one pass at room temperature using a core–sheath billet design. The annealing behavior and shape memory effect of the ECAP specimens were studied followed by post-deformation annealing (PDA) at 673 K for various times. The recrystallization and structural evolution during annealing were investigated by differential scanning calorimetry, dilatometry, X-ray diffraction, transmission electron microscopy and microhardness measurements. The results indicate that the shape memory effect improves by PDA after ECAP processing. Annealing for 10 min gives a good shape memory effect which leads to a maximum in recoverable strain of 6.9 pct upon heating where this is more than a 25 pct improvement compared with the initial state

  20. Effecting change in primary care management of respiratory conditions: a global scoping exercise and literature review of educational interventions to inform the IPCRG's E-Quality initiative.

    Science.gov (United States)

    McDonnell, Juliet; Williams, Siân; Chavannes, Niels H; Correia de Sousa, Jaime; Fardy, H John; Fletcher, Monica; Stout, James; Tomlins, Ron; Yusuf, Osman M; Pinnock, Hilary

    2012-12-01

    This discussion paper describes a scoping exercise and literature review commissioned by the International Primary Care Respiratory Group (IPCRG) to inform their E-Quality programme which seeks to support small-scale educational projects to improve respiratory management in primary care. Our narrative review synthesises information from three sources: publications concerning the global context and health systems development; a literature search of Medline, CINAHL and Cochrane databases; and a series of eight interviews conducted with members of the IPCRG faculty. Educational interventions sit within complex healthcare, economic, and policy contexts. It is essential that any development project considers the local circumstances in terms of economic resources, political circumstances, organisation and administrative capacities, as well as the specific quality issue to be addressed. There is limited evidence (in terms of changed clinician behaviour and/or improved health outcomes) regarding the merits of different educational and quality improvement approaches. Features of educational interventions that were most likely to show some evidence of effectiveness included being carefully designed, multifaceted, engaged health professionals in their learning, provided ongoing support, were sensitive to local circumstances, and delivered in combination with other quality improvement strategies. To be effective, educational interventions must consider the complex healthcare systems within which they operate. The criteria for the IPCRG E-Quality awards thus require applicants not only to describe their proposed educational initiative but also to consider the practical and local barriers to successful implementation, and to propose a robust evaluation in terms of changed clinician behaviour or improved health outcomes.

  1. Education as the (not so) great equalizer : new evidence based on a parental fixed effect analysis for Spain

    OpenAIRE

    BERNARDI, Fabrizio; ARES, Macarena

    2017-01-01

    We investigate whether coming from a higher socio-economic background is associated with greater labour market success, net of own achieved education. We replicate previous analyses on the direct effect of social origin, net of education, for Spain using a more recent and larger dataset that consists of the merged monthly barometer surveys by the Centro de Investigaciones Sociológicas. Compared to previous studies, we use a more refined classification for the respondent’s education and perfor...

  2. Basic and Advanced EMS Providers Are Equally Effective in Naloxone Administration for Opioid Overdose in Northern New England.

    Science.gov (United States)

    Gulec, Nazey; Lahey, Joseph; Suozzi, James C; Sholl, Matthew; MacLean, Charles D; Wolfson, Daniel L

    2018-01-01

    Overdose mortality from illicit and prescription opioids has reached epidemic proportions in the United States, especially in rural areas. Naloxone is a safe and effective agent that has been shown to successfully reverse the effects of opioid overdose in the prehospital setting. The National EMS Scope of Practice Model currently only recommends advanced life support (ALS) providers to administer naloxone; however, some individual states have expanded this scope of practice to include intranasal (IN) administration of naloxone by basic life support (BLS) providers, including the Northern New England states. This study compares the effectiveness and appropriateness of naloxone administration between BLS and ALS providers. All Vermont, New Hampshire, and Maine EMS patient encounters between April 1, 2014 and December 31, 2016 where naloxone was administered were examined and 3,219 patients were identified. The proportion of successful reversals of opioid overdose, based on improvement in the Glasgow Coma Scale (GCS), respiratory rate (RR), and provider global assessment (GA) of response to medication was compared between BLS and ALS providers using a Chi-Squared statistic, Fisher's exact or Wilcoxon rank-sum test. There was no significant difference in the percent improvement in GCS between BLS and ALS (64% and 64% P = 0.94). There was no significant difference in the percentage of improvement in RR between BLS and ALS (45% and 48% P = 0.43). There was a significant difference in the percentage of improvement of GA between BLS and ALS (80% and 67% P < 0.001). There was no significant difference in determining appropriate cases to administer naloxone where RR < 12 and GCS < 15 between BLS and ALS (42% and 43% P = 0.94). BLS providers were as effective as ALS providers in improving patient outcome measures after naloxone administration and in identifying patients for whom administration of naloxone is appropriate. These findings support expanding the National EMS Scope

  3. Light equalization radiography

    International Nuclear Information System (INIS)

    Kruger, R.A.; Reinecke, D.R.; Power, R.L.

    1989-01-01

    An electro-optical, radiographic film dodging technique has been developed that can restore lost image contrast on underexposed regions of radiographs. The device consists of a low-resolution x-ray camera and a scanning, light-exposure array. Both are controlled by a microcomputer. The theory of operation has been developed, and technical requirements for implementing light-equalization radiogrpahy have been defined. Initial clinical results with a prototype have been analyzed and compared with results of conventional films

  4. THE EQUALITY PRINCIPLE REQUIREMENTS

    Directory of Open Access Journals (Sweden)

    CLAUDIA ANDRIŢOI

    2013-05-01

    Full Text Available The problem premises and the objectives followed: the idea of inserting the equality principle between the freedom and the justice principles is manifested in positive law in two stages, as a general idea of all judicial norms and as requirement of the owner of a subjective right of the applicants of an objective law. Equality in face of the law and of public authorities can not involve the idea of standardization, of uniformity, of enlisting of all citizens under the mark of the same judicial regime, regardless of their natural or socio-professional situation. Through the Beijing Platform and the position documents of the European Commission we have defined the integrative approach of equality as representing an active and visible integration of the gender perspective in all sectors and at all levels. The research methods used are: the conceptualist method, the logical method and the intuitive method necessary as means of reasoning in order to argue our demonstration. We have to underline the fact that the system analysis of the research methods of the judicial phenomenon doesn’t agree with “value ranking”, because one value cannot be generalized in rapport to another. At the same time, we must fight against a methodological extremism. The final purpose of this study is represented by the reaching of the perfecting/excellence stage by all individuals through the promotion of equality and freedom. This supposes the fact that the existence of a non-discrimination favourable frame (fairness represents a means and a condition of self-determination, and the state of perfection/excellency is a result of this self-determination, the condition necessary for the obtaining of this nondiscrimination frame for all of us and in conditions of freedom for all individuals, represents the same condition that promotes the state of perfection/excellency. In conclusion we may state the fact that the equality principle represents a true catalyst of the

  5. The effect of encoding condition on free recall in Parkinson's disease: incidental and intentional memory are equally affected.

    Science.gov (United States)

    Ellfolk, Ulla; Huurinainen, Salla; Joutsa, Juho; Karrasch, Mira

    2012-01-01

    Free recall memory deficits are common at early stages of Parkinson's disease (PD). As most studies have used intentional memory tasks, there is little information on how non-intentional, incidental encoding conditions affect memory performance in PD. We studied possible differences between PD patients and controls on free recall using incidental and intentional visual memory tasks. Free recall was examined in relation to attentive/executive functioning and subjective memory complaints. A total of 29 non-demented, medicated PD patients (age 60, disease duration 19 months) and 29 healthy controls (age 61) participated in the study. Incidental free recall was studied using a memory-modification of the Boston naming test (Memo-BNT) and intentional free recall with the 20 Objects test. There was a significant main effect for group due to worse free recall performances in the PD group. No statistically significant interaction between group and encoding condition was observed. The free recall deficit in the PD group was related to cognitive/psychomotor slowing, but not to attentive/executive task demands, or to subjective memory complaints. The results indicate that PD patients are impaired on free recall irrespective of encoding condition.

  6. Nearly equal β* at CESR

    International Nuclear Information System (INIS)

    Bagley, P.; Billing, M.; Krishnagopal, S.; Rubin, D.; Siemann, R.; Welch, J.

    1991-01-01

    Simulations suggest that in e + e - storage rings collisions of round beams (equal emittances and equal β * ) can produce tune shifts of 0.1 and very large luminosities. Further simulations show the same large vertical tune shifts even with very different horizontal and vertical emittances. Using a special CESR lattice with β h * = 32 cm, β v * = 20 cm, and zero horizontal and vertical dispersion at the interaction point, the author authors collided beams with horizontal emittance of 136 nm · rad and vertical emittance of about 9 nm · rad and vertical emittance of about 9 nm · rad. There were experimental complications involving the damping partition numbers, a near miss at a parasitic crossing point, and small orbit offsets at the main collision point. They have done a detailed analysis of these complications and discuss their effects on the observed saturated tune shift of 0.045 ± 0.010

  7. Why the Equal Rights Amendment?

    Science.gov (United States)

    Denmark, Florence L.

    The Equal Rights Amendment proposes to ensure constitutional protection against all legislative sex discrimination. "Separate but Equal" standards, be they legal, social or psychological, are inevitably incompatable with equal protection under the law and act as a barrier to each individual's freedom for self determination. Equal rights,…

  8. Midwives, gender equality and feminism.

    Science.gov (United States)

    Walsh, Denis

    2016-03-01

    Gender inequality and the harmful effects of patriarchy are sustaining the wide spread oppression of women across the world and this is also having an impact on maternity services with unacceptable rates of maternal mortality, the continued under investment in the midwifery profession and the limiting of women's place of birth options. However alongside these effects, the current zeitgeist is affirming an alignment of feminism and gender equality such that both have a high profile in public discourse. This presents a once in a generation opportunity for midwives to self-declare as feminists and commit to righting the wrongs of this most pernicious form of discrimination.

  9. Positive Action in EU Gender Equality Law: promoting more women in corporate decision making?

    NARCIS (Netherlands)

    Ramos Martín, N.E.

    2013-01-01

    Equality is a broad and complex concept with various meanings (equal treatment, equal opportunities, formal equality, and substantive or de facto equality). Although there are strong similarities in the definition of key concepts related to equality, the EU and other international organisation have

  10. No beneficial effect of Polidocanol treatment in Achilles tendinopathy

    DEFF Research Database (Denmark)

    Ebbesen, B H; Mølgaard, C M; Olesen, J L

    2017-01-01

    PURPOSE: Polidocanol injections have been used to treat chronic Achilles tendinopathy in clinical settings, but the few studies published show inconsistent results. The aim of this study was to evaluate the mid-term effect of Polidocanol in patients with chronic Achilles tendinopathy. It was hypo......PURPOSE: Polidocanol injections have been used to treat chronic Achilles tendinopathy in clinical settings, but the few studies published show inconsistent results. The aim of this study was to evaluate the mid-term effect of Polidocanol in patients with chronic Achilles tendinopathy...... of Achilles tendinopathy for at least 3 months and with neovascularisation demonstrated by ultrasonography was included. A minimum of 3 months of eccentric exercise treatment was required before participating. The patients were allocated to a maximum of two injection of either Polidocanol or Lidocaine...... an improvement at 3- and 6-month follow-up, but no mid-term differences between the groups were seen. An equal number of patients in the two groups were satisfied with the treatment at follow-up. CONCLUSIONS: The results indicate that Polidocanol is a safe treatment, but the mid-term effects are the same...

  11. The effectiveness of hypnotherapy in the treatment of subjective tinnitus

    Directory of Open Access Journals (Sweden)

    Shirin Moghtaderi

    2012-12-01

    Full Text Available Background and Aim: Tinnitus is an annoying disease cause major problems including insomnia, impaired concentration, and reduced quality of life. This study aimed to investigate the effectiveness of hypnotherapy in the treatment of subjective tinnitus.Methods: This was a pilot experimental study with pre- and post-test method. 20 people suffered from subjective tinnitus were divided equally in two groups of experimental and control. The two groups were matched according to age and severity of tinnitus. They completed tinnitus clinical questionnaires before and after the test and the severity of their tinnitus was recorded by a number from one to ten. Experimental group went under hypnotherapy for 10 sessions. The control group did not perform any psychological treatment. The gathered data were statistically analyzed using Student's t-test (independent and dependent.Results: There were significant differences between the pre-test and post-test scores of each group and also, between the post-test scores of experimental and control groups (p = 0.001 for all.Conclusion: The results showed that hypnotherapy could effectively reduce the seventy of tinnitus in patients in the experimental group; in other words, the results confirm the effectiveness of medical hypnosis in the treatment of subjective tinnitus.

  12. Cost-Effective Fuel Treatment Planning

    Science.gov (United States)

    Kreitler, J.; Thompson, M.; Vaillant, N.

    2014-12-01

    The cost of fighting large wildland fires in the western United States has grown dramatically over the past decade. This trend will likely continue with growth of the WUI into fire prone ecosystems, dangerous fuel conditions from decades of fire suppression, and a potentially increasing effect from prolonged drought and climate change. Fuel treatments are often considered the primary pre-fire mechanism to reduce the exposure of values at risk to wildland fire, and a growing suite of fire models and tools are employed to prioritize where treatments could mitigate wildland fire damages. Assessments using the likelihood and consequence of fire are critical because funds are insufficient to reduce risk on all lands needing treatment, therefore prioritization is required to maximize the effectiveness of fuel treatment budgets. Cost-effectiveness, doing the most good per dollar, would seem to be an important fuel treatment metric, yet studies or plans that prioritize fuel treatments using costs or cost-effectiveness measures are absent from the literature. Therefore, to explore the effect of using costs in fuel treatment planning we test four prioritization algorithms designed to reduce risk in a case study examining fuel treatments on the Sisters Ranger District of central Oregon. For benefits we model sediment retention and standing biomass, and measure the effectiveness of each algorithm by comparing the differences among treatment and no treat alternative scenarios. Our objective is to maximize the averted loss of net benefits subject to a representative fuel treatment budget. We model costs across the study landscape using the My Fuel Treatment Planner software, tree list data, local mill prices, and GIS-measured site characteristics. We use fire simulations to generate burn probabilities, and estimate fire intensity as conditional flame length at each pixel. Two prioritization algorithms target treatments based on cost-effectiveness and show improvements over those

  13. Impact of Treatment Integrity on Intervention Effectiveness

    Science.gov (United States)

    Fryling, Mitch J.; Wallace, Michele D.; Yassine, Jordan N.

    2012-01-01

    Treatment integrity has cogent implications for intervention effectiveness. Understanding these implications is an important, but often neglected, undertaking in behavior analysis. This paper reviews current research on treatment integrity in applied behavior analysis. Specifically, we review research evaluating the relation between integrity…

  14. Medium-chain triglyceride-rich enteral nutrition is more effective than low-fat enteral nutrition in rat colitis, but is equal in enteritis.

    Science.gov (United States)

    Tsujikawa, T; Ohta, N; Nakamura, T; Yasuoka, T; Satoh, J; Fukunaga, T; Itohi, A; Uda, K; Ihara, T; Andoh, A; Sasaki, M; Fujiyama, Y; Bamba, T

    2001-10-01

    Although enteral nutrition (EN) therapy for Crohn's disease has been confirmed to be as effective as steroid therapy, the precise mechanism responsible for the effects of EN remains unclear, although some of the therapeutic effects of EN are believed to be due to a low dietary fat content. In order to elucidate the influence of fat in EN, it is important to investigate not only the quantity of fat, but also the source of the fat. We compared two enteral nutritional formulae: Elental (Ajinomoto) (elemental diet; ED), which contains only 1.5% fat, provided as long-chain triglycerides (LCT), versus Twinline (Snow Brand Milk Products) (TL), which contains a high percentage of fat (20.4%), provided mainly as medium-chain triglycerides (MCT). These formulae were tested on rat enteritis and rat colitis induced by trinitrobenzene sulfonic acid (TNBS). Both ED and TL reduced the manifestations of enteritis. TL had a stronger anti-inflammatory effect than ED for colitis. TL also had nutritional advantages as compared with ED, as shown by the total serum protein in the TL group being significantly higher than that in the ED group. The results indicate that intraluminal MCT is suitable as a fat energy source during intestinal inflammation in rats. We suggest that Twinline may be more useful to improve nutritional status and to reduce the mucosal inflammation in rat colitis, but that Twinline is equal in effect to Elental for rat enteritis.

  15. Understanding placebo, nocebo, and iatrogenic treatment effects.

    Science.gov (United States)

    Bootzin, Richard R; Bailey, Elaine T

    2005-07-01

    Placebo and nonplacebo treatments have both positive and negative effects on patient outcomes. To better understand the patterning of treatment effects, three specific interventions will be discussed that are reported to produce more harm than benefit: critical incident stress debriefing, group therapy for adolescents with conduct disorders, and psychotherapy for dissociative identity disorder. In each case, there is an interaction between mechanisms thought to underlie both placebo and specific treatment effects. Mechanisms hypothesized to underlie placebo and nocebo effects include patient expectancy, self-focused attention to symptoms, motivation to change, and sociocultural role-enactment cues. In the three treatments discussed, specific mechanisms interact with nonspecific mechanisms to produce iatrogenic effects. To advance knowledge, it is important both to specify the theory of treatment and its expected outcomes and to put the theory to test. Only with attention to the empirical findings from programmatic research of specific and nonspecific effects and their interaction is it possible to improve the outcomes of treatment beyond the status quo.

  16. The effects of two equal-volume training protocols upon strength, body composition and salivary hormones in male rugby union players

    Directory of Open Access Journals (Sweden)

    BT Crewther

    2016-04-01

    Full Text Available This study examined the effects of two equal-volume resistance-training protocols upon strength, body composition and salivary hormones in male rugby union players. Using a crossover design, 24 male rugby players completed a 4-week full-body (FB and split-body (SB training protocol of equal volume during the competitive season. One repetition maximum (1RM strength, body composition via skinfold measurements and salivary testosterone (T and cortisol (C concentrations were assessed pre and post training. The FB and SB protocols improved upper (7.3% and 7.4% and lower body 1RM strength (7.4% and 5.4%, whilst reducing body fat (-0.9% and -0.4% and fat mass (-5.7% and -2.1%, respectively (all p ≤ 0.021. The SB protocol elevated T (21% and C (50% concentrations with a higher T/C ratio (28% after FB training (all p ≤ 0.039. The strength changes were similar, but the body composition and hormonal results differed by protocol. Slope testing on the individual responses identified positive associations (p ≤ 0.05 between T and C concentrations and absolute 1RM strength in stronger (squat 1RM = 150.5 kg, but not weaker (squat 1RM = 117.4 kg, men. A short window of training involving FB or SB protocols can improve strength and body composition in rugby players. The similar strength gains highlight training volume as a key adaptive stimulus, although the programme structure (i.e. FB or SB did influence the body composition and hormonal outcomes. It also appears that 1RM strength is associated with individual hormonal changes and baseline strength.

  17. The effects of two equal-volume training protocols upon strength, body composition and salivary hormones in male rugby union players

    Science.gov (United States)

    Heke, TOL; Keogh, JWL

    2016-01-01

    This study examined the effects of two equal-volume resistance-training protocols upon strength, body composition and salivary hormones in male rugby union players. Using a crossover design, 24 male rugby players completed a 4-week full-body (FB) and split-body (SB) training protocol of equal volume during the competitive season. One repetition maximum (1RM) strength, body composition via skinfold measurements and salivary testosterone (T) and cortisol (C) concentrations were assessed pre and post training. The FB and SB protocols improved upper (7.3% and 7.4%) and lower body 1RM strength (7.4% and 5.4%), whilst reducing body fat (-0.9% and -0.4%) and fat mass (-5.7% and -2.1%), respectively (all p ≤ 0.021). The SB protocol elevated T (21%) and C (50%) concentrations with a higher T/C ratio (28%) after FB training (all p ≤ 0.039). The strength changes were similar, but the body composition and hormonal results differed by protocol. Slope testing on the individual responses identified positive associations (p ≤ 0.05) between T and C concentrations and absolute 1RM strength in stronger (squat 1RM = 150.5 kg), but not weaker (squat 1RM = 117.4 kg), men. A short window of training involving FB or SB protocols can improve strength and body composition in rugby players. The similar strength gains highlight training volume as a key adaptive stimulus, although the programme structure (i.e. FB or SB) did influence the body composition and hormonal outcomes. It also appears that 1RM strength is associated with individual hormonal changes and baseline strength. PMID:27274103

  18. Equality Matters: The Critical Implications of Precisely Defining Equality

    Science.gov (United States)

    Faulkner, Valerie; Walkowiak, Temple; Cain, Chris; Lee, Carrie

    2016-01-01

    Equality is such an important concept for children to develop. In this article it is argued that a precise definition is needed to ensure that students are provided with a consistent "picture" of what it is that equality really means.

  19. Infiltrative local anesthesia with articaine is equally as effective as inferior alveolar nerve block with lidocaine for the removal of erupted molars.

    Science.gov (United States)

    Venkat Narayanan, J; Gurram, Prashanthi; Krishnan, Radhika; Muthusubramanian, Veerabahu; Sadesh Kannan, V

    2017-09-01

    The aim of this study is to assess the efficacy of 4% articaine with 1:100,000 adrenaline given as buccal and lingual infiltration in adult patients undergoing erupted mandibular first and second molar teeth extraction versus inferior alveolar nerve block technique using 2% lignocaine with 1:80,000 adrenaline. A total of 100 patients undergoing extraction of mandibular posterior teeth were divided into two equally matched groups for the study, out of which 50 patients were given 4% articaine with 1:100,000 adrenaline as buccal and lingual infiltration and 50 patients were given 2% lignocaine with 1:80,000 adrenaline using classic direct inferior alveolar nerve block with lingual and buccal nerve block. Efficacy of anesthesia was determined using a numeric analog scale (NAS) ranging from 0 indicating no pain to 10 indicating the worst pain imaginable. The NAS was taken by a different operator to avoid bias. The pain scores in both groups were analyzed using the Mann-Whitney U test, and a p value of 0.338 was obtained which is not statistically significant. Hence, no significant difference in the pain score was established between both groups. The adverse effects of both the local anesthetics if any were noted. From this study, we concluded that the use of 4% articaine with 1:100,000 adrenaline is as effective as inferior alveolar nerve block with lignocaine but without the risk of attendant adverse effects of inferior alveolar nerve block technique.

  20. Economic growth and gender equality | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    And conversely, does gender equality impact economic growth? ... change and growth in the economy on women's employment opportunities and the type ... sectors and their overall effect on development outcomes, such as economic growth ...

  1. Adaptive histogram equalization and its variations

    NARCIS (Netherlands)

    Pizer, S.M.; Amburn, E.P.; Austin, J.D.; Cromartie, R.; Geselowitz, A.; Greer, Trey; Haar Romenij, ter B.M.; Zimmerman, J.B.; Zuiderveld, K.J.

    1987-01-01

    Adaptive histogram equalization (ahe) is a contrast enhancement method designed to be broadly applicable and having demonstrated effectiveness. However, slow speed and the overenhancement of noise it produces in relatively homogeneous regions are two problems. We report algorithms designed to

  2. Gender Summit 2011: Equality Research and Innovation Through Equality

    Czech Academy of Sciences Publication Activity Database

    Tenglerová, Hana

    2011-01-01

    Roč. 19, č. 2 (2011), s. 72-74 ISSN 1210-6658. [European Gender Summit 2011: Equality Research and Innovation Through Equality . Brusel, 07.11.2011-08.11.2011] R&D Projects: GA MŠk OK08007 Institutional research plan: CEZ:AV0Z70280505 Keywords : gender equality * science * policy Subject RIV: AO - Sociology, Demography

  3. 36 CFR 254.12 - Value equalization; cash equalization waiver.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Value equalization; cash... AGRICULTURE LANDOWNERSHIP ADJUSTMENTS Land Exchanges § 254.12 Value equalization; cash equalization waiver. (a..., either with or without adjustments of relative values as compensation for various costs, the parties to...

  4. Getting to Equal : Promoting Gender Equality through Human Development

    OpenAIRE

    World Bank

    2011-01-01

    To achieve gender equality and empower women, it is essential to invest in human development. The World Development Report 2012: Gender Equality and Development (hereafter WDR 2012) brings the best global evidence to bear on the relationship between gender equality and development. A central theme running through the report is how investments and outcomes in human development namely health...

  5. Advances in surface treatments: Technology, applications, effects

    International Nuclear Information System (INIS)

    Niku-Lari, A.

    1987-01-01

    An international handbook has been produced to include all aspects of residual stresses, including the theoretical background, effects of residual stresses, measurement and calculation and quantitative assessment of residual stress effects. Techniques for altering residual stresses, particularly surface treatments, are discussed. Up to date information on the state of the art is presented. (UK)

  6. Internationalisation and Equality

    Directory of Open Access Journals (Sweden)

    Louise Ackers

    2010-12-01

    Full Text Available This paper examines the “tension” in the debate around human resources in science between the promotion of internationalisation and mobility, on the one hand, and the promotion of equality and work-life balance, on the other. In an attempt to move away from the current polarity of mobility-immobility and understand the importance of viewing mobility as a continuum, the paper emphasises the contribution of new forms of mobility and particularly of short stays to the internationalisation process that has become so critical to career progression. It illustrates the specific opportunities that certain forms of short-stay mobility present both in terms of optimizing knowledge exchange processes and “internationalisation” but also to “potentially mobile” women and men with personal and caring obligations. Attention to the “far end” of the continuum draws attention to the role that “business visits” and on-going “travel” play in career enhancement. Migration research has rather neglected these forms of movement. Recent research on business travel would suggest that these forms of movement are highly gendered and present unique challenges to people with personal and caring responsibilities.

  7. Gender equality in primary immunisation

    Directory of Open Access Journals (Sweden)

    Deepak S Khismatrao

    2015-01-01

    Full Text Available Context: Immunization, a well-known and effective method of preventing childhood illnesses is basic service under primary health care. Most surveys in India measure primary immunization coverage and quality, but no "Gender Equality." Aims: Assess "Gender Equality" in primary immunization with reference to coverage, quality, and place of immunization. Settings and Design: Cross-sectional survey in a primary health center, Pune, Maharashtra using World Health Organization 30-cluster sampling method with 14 beneficiaries (7 girls and 7 boys to be selected from each cluster. Instead of 420 children, data collected for 345 children, as requisite numbers of children were not available in low population villages and also children whose mothers were not present during survey were excluded. Materials and Methods: Vaccination data collected from either records and/or history by mother. Children born on or between 13-09-2009 and 13-09-2010, were included. Statistical Analysis Used: SPSS 14.01 version with Chi-square as test of significance. Results: Of the study population, 171 (49.6% were females and 174 (50.4% males. A total of 64.1% children had immunization records with female proportion 69.0% and males 59.2%. Primary immunization coverage was 80.0%, with female proportion 82.5% and males 77.6%. One male child was completely unimmunized and remaining partially immunized, with unaware of schedule and illness of child being major reasons for partial immunization. There was no gender wise statistically significant difference observed in Primary Immunization with reference to coverage, quality, and place of immunization. Conclusions: Immunization coverage is nearing 85% benchmark with major contribution from Universal Immunization Program. Gender Equality observed in primary immunization. Preservation of immunization records by community and timely vaccinations are areas for improvement.

  8. SARS: systematic review of treatment effects.

    Directory of Open Access Journals (Sweden)

    Lauren J Stockman

    2006-09-01

    Full Text Available BACKGROUND: The SARS outbreak of 2002-2003 presented clinicians with a new, life-threatening disease for which they had no experience in treating and no research on the effectiveness of treatment options. The World Health Organization (WHO expert panel on SARS treatment requested a systematic review and comprehensive summary of treatments used for SARS-infected patients in order to guide future treatment and identify priorities for research. METHODS AND FINDINGS: In response to the WHO request we conducted a systematic review of the published literature on ribavirin, corticosteroids, lopinavir and ritonavir (LPV/r, type I interferon (IFN, intravenous immunoglobulin (IVIG, and SARS convalescent plasma from both in vitro studies and in SARS patients. We also searched for clinical trial evidence of treatment for acute respiratory distress syndrome. Sources of data were the literature databases MEDLINE, EMBASE, BIOSIS, and the Cochrane Central Register of Controlled Trials (CENTRAL up to February 2005. Data from publications were extracted and evidence within studies was classified using predefined criteria. In total, 54 SARS treatment studies, 15 in vitro studies, and three acute respiratory distress syndrome studies met our inclusion criteria. Within in vitro studies, ribavirin, lopinavir, and type I IFN showed inhibition of SARS-CoV in tissue culture. In SARS-infected patient reports on ribavirin, 26 studies were classified as inconclusive, and four showed possible harm. Seven studies of convalescent plasma or IVIG, three of IFN type I, and two of LPV/r were inconclusive. In 29 studies of steroid use, 25 were inconclusive and four were classified as causing possible harm. CONCLUSIONS: Despite an extensive literature reporting on SARS treatments, it was not possible to determine whether treatments benefited patients during the SARS outbreak. Some may have been harmful. Clinical trials should be designed to validate a standard protocol for dosage

  9. Musical hallucinations: review of treatment effects

    Directory of Open Access Journals (Sweden)

    Jan eCoebergh

    2015-06-01

    Full Text Available AbstractBackground: Despite an increased scientific interest in musical hallucinations throughout the past 25 years, treatment protocols are still lacking. This may well be due to the fact that musical hallucinations have multiple causes, and that published cases are relatively rare.Objective: To review the effects of published treatment methods for musical hallucinations.Methods: A literature search yielded 175 articles discussing a total number of 516 cases, of which 147 articles discussed treatment in 276 individuals. We analysed the treatment results in relation to the aetiological factor considered responsible for the mediation of the musical hallucinations, i.e., idiopathic/hypoacusis, psychiatric disorder, brain lesion and other pathology, epilepsy or intoxication.Results: Musical hallucinations can disappear without intervention. When hallucinations are bearable, patients can be reassured without any other treatment. However, in other patients musical hallucinations are so disturbing that treatment is indicated. Distinct aetiological groups appear to respond differently to treatment. In the hypoacusis group, treating the hearing impairment can yield significant improvement and coping strategies (e.g. more acoustic stimulation are frequently helpful. Pharmacological treatment methods can also be successful, with antidepressants being more helpful than antiepileptics (which are still better than antipsychotics. The limited use of acetylcholinesterase inhibitors has looked promising. Musical hallucinations occurring as part of a psychiatric disorder tend to respond well to psychopharmacological treatments targeting the underlying disorder. Musical hallucinations experienced in the context of brain injuries and epilepsy tend to respond well to antiepileptics, but their natural course is often benign, irrespective of any pharmacological treatment. When intoxication is the main aetiological factor, it is important to stop or switch the

  10. Gender equality and women empowerment.

    Science.gov (United States)

    Dargan, R

    1996-01-01

    This article lists 11 suggestions for empowering women that the government of India should take, if it has a sincere commitment to gender equality and women's empowerment grounded in social change and not just rhetoric: 1) education should be made compulsory for all female children and places held on a 50/50 basis in all technical institutions; 2) a uniform civil code should be adopted for all citizens regardless of cast, creed, and religion; 3) women should have an equal right to own property and receive inheritance; 4) the National Women's Commission should be enlarged, representative of diversity, and effective in making policy decisions related to welfare, education, recruitment, and promotion; 5) a State Women's Commission should be established with affiliates at the block, district, and division levels; 6) the National and State Women's Commission should be established as a Statutory Body with binding decisions mandating government action; 7) the National and State Women's Commissions should have transparent functions, be regulatory, and offer workshops and seminars for women; 8) state governments should not interfere in the functions of National and State Women's Commissions; 9) women should fill 50% of all Center and State government service posts and concessions should be made on minimum academic qualifications and completed years of service, until all positions are filled; 10) 50% of the seats of Parliament should be reserved for women in both the State Legislature, Council of Ministry Boards, Corporations, Committees, and Commissions; and 11) the Constitution should provide for women judges in courts of law.

  11. Treatment Effect on Recidivism for Juveniles Who Have Sexually Offended: a Multilevel Meta-Analysis.

    Science.gov (United States)

    Ter Beek, Ellis; Spruit, Anouk; Kuiper, Chris H Z; van der Rijken, Rachel E A; Hendriks, Jan; Stams, Geert Jan J M

    2018-04-01

    The current study investigated the effect on recidivism of treatment aimed at juveniles who have sexually offended. It also assessed the potential moderating effect of type of recidivism, and several treatment, participant and study characteristics. In total, 14 published and unpublished primary studies, making use of a comparison group and reporting on official recidivism rates, were included in a multilevel meta-analysis. This resulted in the use of 77 effect sizes, and 1726 participants. A three-level meta-analytic model was used to calculate the combined effect sizes (Cohens d) and to perform moderator analyses. Study quality was assessed with the EPHPP Quality Assessment Tool for Quantitative Studies. A moderate effect size was found (d = 0.37), indicating that the treatment groups achieved an estimated relative reduction in recidivism of 20.5% as compared to comparison groups. However, after controlling for publication bias, a significant treatment effect was no longer found. Type of recidivism did not moderate the effect of treatment, indicating that treatment groups were equally effective for all types of recidivism. Also, no moderating effects of participant or treatment characteristics were found. Regarding study characteristics, a shorter follow up time showed a trend for larger effect sizes, and the effect size calculation based on proportions yielded larger effect sizes than calculation via mean frequency of offending. Implications for future research and clinical practice are discussed.

  12. Neurocognitive Effects of Treatment for Childhood Cancer

    Science.gov (United States)

    Butler, Robert W.; Haser, Jennifer K.

    2006-01-01

    We review research on the neuropsychological effects that central nervous system (CNS) cancer treatments have on the cognitive abilities of children and adolescents. The authors focus on the two most common malignancies of childhood: leukemias and brain tumors. The literature review is structured so as to separate out earlier studies, generally…

  13. Evaluating the Effectiveness Of Postfire Rehabilitation Treatments

    Science.gov (United States)

    Peter R. Robichaud; Jan L. Beyers; Daniel G. Neary

    2000-01-01

    Spending on postfire emergency watershed rehabilitation has increased during the past decade. A west-wide evaluation of USDA Forest Service burned area emergency rehabilitation (BAER) treatment effectiveness was undertaken as a joint project by USDA Forest Service Research and National Forest System staffs. This evaluation covers 470 fires and 321 BAER projects, from...

  14. Effect of equal-channel angular pressing and annealing conditions on the texture, microstructure, and deformability of an MA2-1 alloy

    Science.gov (United States)

    Serebryany, V. N.; Ivanova, T. M.; Kopylov, V. I.; Dobatkin, S. V.; Pozdnyakova, N. N.; Pimenov, V. A.; Savelova, T. I.

    2010-07-01

    Equal-channel angular pressing (ECAP) of am MA2-1 alloy according to routes A and Bc is used to study the possibility of increasing the low-temperature deformability of the alloy due to grain refinement and a change in its texture. To separate the grain refinement effect from the effect of texture on the deformability of the alloy, samples after ECAP are subjected to recrystallization annealing that provides grain growth to the grain size characteristic of the initial state (IS) of the alloy. Upon ECAP, the average grain size is found to decrease to 2-2.4 μm and the initial sharp axial texture changes substantially (it decomposes into several scattered orientations). The type of orientations and the degree of their scattering depend on the type of ECAP routes. The detected change in the texture is accompanied by an increase in the deformability parameters (normal plastic anisotropy coefficient R, strain-hardening exponent n, relative uniform elongation δu) determined upon tensile tests at 20°C for the states of the alloy formed in the IS-4A-4Bc and IS-4Ao-4BcO sequences. The experimental values of R agree with the values calculated in terms of the Taylor model of plastic deformation in the Bishop-Hill approximation using quantitative texture data in the form of orientation distribution function coefficients with allowance for the activation of prismatic slip, especially for ECAP routes 4Bc and 4BcO. When the simulation results, the Hall-Petch relation, and the generalized Schmid factors are taken into account, a correlation is detected between the deformability parameter, the Hall-Petch coefficient, and the ratio of the critical shear stresses on prismatic and basal planes.

  15. An investigation into the effect of equal channel angular extrusion process on mechanical and microstructural properties of middle layer in copper clad aluminum composite

    International Nuclear Information System (INIS)

    Tolaminejad, B.; Karimi Taheri, A.; Arabi, H.; Shahmiri, M.

    2009-01-01

    Equal channel angular extrusion is a promising technique for production of ultra fine-grain materials of few hundred nanometers size. In this research, the grain refinement of aluminium strip is accelerated by sandwiching it between two copper strips and then subjecting the three strips to Equal channel angular extrusion process simultaneously. The loosely packed copper-aluminium-copper laminated billet was passed through Equal channel angular extrusion die up to 8 passes using the Bc route. Then, tensile properties and some microstructural characteristics of the aluminium layer were evaluated. The scanning and transmission electron microscopes, and X-ray diffraction were used to characterize the microstructure. The results show that the yield stress of middle layer (Al) is increased significantly by about four times after application of Equal channel angular extrusion throughout the four consecutive passes and then it is slightly decreased when more Equal channel angular extrusion passes are applied. An ultra fine grain within the range of 500 to 600 nm was obtained in the Al layer by increasing the thickness of the copper layers. lt was observed that the reduction of grain size in the aluminium layer is nearly 55% more than that of a equal channel angular-extruded single layer aluminium billet, i.e. extruding a single aluminium strip or a billet without any clad for the same amount of deformation. This behaviour was attributed to the higher rates of dislocations interaction and cell formation and texture development during the Equal channel angular extrusion of the laminated composite compared to those of a single billet.

  16. THE CONSTITUTIONAL PRINCIPLE OF EQUALITY - LEGAL SIGNIFICANCE AND SOCIAL IMPLICATIONS -

    Directory of Open Access Journals (Sweden)

    Marius ANDREESCU

    2017-12-01

    Full Text Available The equality in human rights and obligations, the equality of citizens before the law are fundamental categories of the theories on social democracy but also conditions of the lawful state, without which constitutional democracy cannot be conceived. In Romanian Constitution, this principle is consecrated in the form of equality of the citizens before the law and public authorities. There are also particular aspects of this principle consecrated in the Constitution. The constitutional principle of equality requires that equal treatment be applied to equal situations. This social and legal reality implies numerous interferences between the principle of equality and other constitutional principles. In this study, by using theoretical and jurisprudential arguments, we intend to demonstrate that, in relation to contemporary social reality, equality, as a constitutional principle, is a particular aspect of the principle of proportionality. The latter one expresses in essence the ideas of: fairness, justice, reasonableness and fair appropriateness of state decisions to the facts and legitimate aims proposed.

  17. Side effects of endobronchial laser treatment

    Energy Technology Data Exchange (ETDEWEB)

    Dierkesmann, R.; Huzly, A.

    1985-03-01

    Side effects that have occurred in over 250 endobronchial laser treatments are reported. The laser has been used in severe tracheal and in bronchial obstructions. In two cases significant bleeding had to be treated with tamponade. In one patient an emphysema of the mediastinum developed, in 2 further patients a small pneumothorax. Perforation of the airway was not detected and no special treatment was necessary. Three patients with life-threatening tracheal stenoses and one patient with severe stenosis of both the mainstem bronchi due to metastasis in the bifurcation lymph node had a large defect in the tracheal or bronchial wall with a deep necrosis five to twelve weeks after laser treatment; all these patients had extensive radiotherapy in addition. One patient died due to severe respiratory insufficiency, probably caused by smoke intoxication. After the laser treatment, rubber-like fibrin-rich plaques may develop, which can lead to life-threatening obstructions of the airway. It is recommended that laser bronchoscopy should be performed with the rigid bronchoscope. After treatment of tracheal lesion an endoscopic check must be performed within 24 hours. The combination of laser treatment and radiotherapy seems to involve a certain risk of large defects in the bronchial wall due to necrosis of the tumor.

  18. CAPN1, CAST, and DGAT1 genetic effects on preweaning performance, carcass quality traits, and residual variance of tenderness in a beef cattle population selected for haplotype and allele equalization

    Science.gov (United States)

    Genetic marker effects and type of inheritance are estimated with poor precision when minor marker allele frequencies are low. A stable composite population (MARC III) was subjected to marker assisted selection for multiple years to equalize specific marker frequencies to 1) estimate effect size an...

  19. Algorithms for adaptive histogram equalization

    International Nuclear Information System (INIS)

    Pizer, S.M.; Austin, J.D.; Cromartie, R.; Geselowitz, A.; Ter Haar Romeny, B.; Zimmerman, J.B.; Zuiderveld, K.

    1986-01-01

    Adaptive histogram equalization (ahe) is a contrast enhancement method designed to be broadly applicable and having demonstrated effectiveness [Zimmerman, 1985]. However, slow speed and the overenhancement of noise it produces in relatively homogeneous regions are two problems. The authors summarize algorithms designed to overcome these and other concerns. These algorithms include interpolated ahe, to speed up the method on general purpose computers; a version of interpolated ahe designed to run in a few seconds on feedback processors; a version of full ahe designed to run in under one second on custom VLSI hardware; and clipped ahe, designed to overcome the problem of overenhancement of noise contrast. The authors conclude that clipped ahe should become a method of choice in medical imaging and probably also in other areas of digital imaging, and that clipped ahe can be made adequately fast to be routinely applied in the normal display sequence

  20. Toxic Stress: Effects, Prevention and Treatment

    Directory of Open Access Journals (Sweden)

    Hillary A. Franke

    2014-11-01

    Full Text Available Children who experience early life toxic stress are at risk of long-term adverse health effects that may not manifest until adulthood. This article briefly summarizes the findings in recent studies on toxic stress and childhood adversity following the publication of the American Academy of Pediatrics (AAP Policy Report on the effects of toxic stress. A review of toxic stress and its effects is described, including factors of vulnerability, resilience, and the relaxation response. An integrative approach to the prevention and treatment of toxic stress necessitates individual, community and national focus.

  1. Reforming Equalization: Balancing Efficiency, Entitlement and Ownership

    Directory of Open Access Journals (Sweden)

    Bev Dahlby

    2014-08-01

    Full Text Available In this paper, we provide an overview of the equalization grant system in Canada and the issues that have been raised concerning the reform of the fiscal transfer system. Any reforms to the equalization grant system have to balance three concerns — “efficiency” effects that arise through federal financing of transfers, and the incentive effects on provincial fiscal policies, “entitlement” to reasonably comparable public services at reasonably comparable levels of taxation, and “ownership” of resources and independence of fiscal policies by provincial governments. Five proposals for reform of the equalization system are discussed. With regard to the inclusion rate for resource revenues in equalization formula, we argue that the rate should be reduced from 50 per cent to 25 per cent and that ceiling on total equalization payments should be eliminated. We argue against the proposal to exempt from the calculation of equalization entitlements that are deposited in provincial sovereign wealth funds because this would not reduce total equalization entitlements in present value terms, it would be complex to implement if it extended to all forms of savings by provinces (such as debt reduction, and it would not alter the resource rich provinces’ incentives to save more of their resource revenues. We argue against a proposal to reduce CHT and CST to provinces with above average fiscal capacities because this would reduce their incentive to develop and tax their resources, and it would be counter to the purpose of these block grants, which is to reduce the vertical fiscal imbalance between the federal and the provincial governments. We review the Gusen (2012a proto-type model for incorporating variations in costs and needs in the computation of the equalization entitlements and argue that this procedure seems feasible and merits further analysis.

  2. Gender equality and equal opportunity mechanisms in Italy

    Directory of Open Access Journals (Sweden)

    Mršević Zorica

    2007-01-01

    Full Text Available As a country of Southern European mentality Italy may be taken as the nearest-to-the-Balkans model of the gender equality mechanisms and necessity of their existence. Italy also might be taken as a model of domain and methods of functioning of the gender equality mechanisms as well as their connections with the EU development funds. Besides the Italian Ministry for Rights and Equal opportunities and the National Committee, the attention was paid to the whole range of local mechanisms and legal regulations dealing with advancement of women’s employment and counteracting discrimination on the labor market. In the text are analyzed through the five chapters the Italian mechanisms/institutions for gender equality as located within the European institutional environment but also within the context of Italian recent history of struggle against gender based discrimination. It was stressed that the essence of the accumulated European institutional wisdom is in diversity of the gender equality bodies rather then in their uniformity. Although the Italian mechanisms for gender equality are part of the European institutional environment their aim is to meet the internal needs for advancement of gender equality. Besides, the mechanisms also meet the demands of the international standards comprised in the documents issued by the UN and the EU. In European countries these mechanisms are frequently established and function in the domains of the labor and employment regulations, but also are located within the human rights portfolios while somewhere are connected with the minority rights and equal opportunity implementation.

  3. Reframing Inclusive Education: Educational Equality as Capability Equality

    Science.gov (United States)

    Terzi, Lorella

    2014-01-01

    In this paper, I argue that rethinking questions of inclusive education in the light of the value of educational equality--specifically conceived as capability equality, or genuine opportunities to achieve educational functionings--adds some important insights to the current debate on inclusive education. First, it provides a cohesive value…

  4. Resistance Training with Single vs. Multi-joint Exercises at Equal Total Load Volume: Effects on Body Composition, Cardiorespiratory Fitness, and Muscle Strength.

    Science.gov (United States)

    Paoli, Antonio; Gentil, Paulo; Moro, Tatiana; Marcolin, Giuseppe; Bianco, Antonino

    2017-01-01

    The present study aimed to compare the effects of equal-volume resistance training performed with single-joint (SJ) or multi-joint exercises (MJ) on VO 2 max, muscle strength and body composition in physically active males. Thirty-six participants were divided in two groups: SJ group ( n = 18, 182.1 ± 5.2, 80.03 ± 2.78 kg, 23.5 ± 2.7 years) exercised with only SJ exercises (e.g., dumbbell fly, knee extension, etc.) and MJ group ( n = 18, 185.3 ± 3.6 cm, 80.69 ± 2.98 kg, 25.5 ± 3.8 years) with only MJ exercises (e.g., bench press, squat, etc.). The total work volume (repetitions × sets × load) was equated between groups. Training was performed three times a week for 8 weeks. Before and after the training period, participants were tested for VO 2 max, body composition, 1 RM on the bench press, knee extension and squat. Analysis of covariance (ANCOVA) was used to compare post training values between groups, using baseline values as covariates. According to the results, both groups decreased body fat and increased fat free mass with no difference between them. Whilst both groups significantly increased cardiorespiratory fitness and maximal strength, the improvements in MJ group were higher than for SJ in VO 2 max (5.1 and 12.5% for SJ and MJ), bench press 1 RM (8.1 and 10.9% for SJ and MJ), knee extension 1 RM (12.4 and 18.9% for SJ and MJ) and squat 1 RM (8.3 and 13.8% for SJ and MJ). In conclusion, when total work volume was equated, RT programs involving MJ exercises appear to be more efficient for improving muscle strength and maximal oxygen consumption than programs involving SJ exercises, but no differences were found for body composition.

  5. Americans misperceive racial economic equality.

    Science.gov (United States)

    Kraus, Michael W; Rucker, Julian M; Richeson, Jennifer A

    2017-09-26

    The present research documents the widespread misperception of race-based economic equality in the United States. Across four studies ( n = 1,377) sampling White and Black Americans from the top and bottom of the national income distribution, participants overestimated progress toward Black-White economic equality, largely driven by estimates of greater current equality than actually exists according to national statistics. Overestimates of current levels of racial economic equality, on average, outstripped reality by roughly 25% and were predicted by greater belief in a just world and social network racial diversity (among Black participants). Whereas high-income White respondents tended to overestimate racial economic equality in the past, Black respondents, on average, underestimated the degree of past racial economic equality. Two follow-up experiments further revealed that making societal racial discrimination salient increased the accuracy of Whites' estimates of Black-White economic equality, whereas encouraging Whites to anchor their estimates on their own circumstances increased their tendency to overestimate current racial economic equality. Overall, these findings suggest a profound misperception of and unfounded optimism regarding societal race-based economic equality-a misperception that is likely to have any number of important policy implications.

  6. Are all hands-on activities equally effective? Effect of using plastic models, organ dissections, and virtual dissections on student learning and perceptions.

    Science.gov (United States)

    Lombardi, Sara A; Hicks, Reimi E; Thompson, Katerina V; Marbach-Ad, Gili

    2014-03-01

    This study investigated the impact of three commonly used cardiovascular model-assisted activities on student learning and student attitudes and perspectives about science. College students enrolled in a Human Anatomy and Physiology course were randomly assigned to one of three experimental groups (organ dissections, virtual dissections, or plastic models). Each group received a 15-min lecture followed by a 45-min activity with one of the treatments. Immediately after the lesson and then 2 mo later, students were tested on anatomy and physiology knowledge and completed an attitude survey. Students who used plastic models achieved significantly higher overall scores on both the initial and followup exams than students who performed organ or virtual dissections. On the initial exam, students in the plastic model and organ dissection treatments scored higher on anatomy questions than students who performed virtual dissections. Students in the plastic model group scored higher than students who performed organ dissections on physiology questions. On the followup exam, when asked anatomy questions, students in the plastic model group scored higher than dissection students and virtual dissection students. On attitude surveys, organ dissections had higher perceived value and were requested for inclusion in curricula twice as often as any other activity. Students who performed organ dissections were more likely than the other treatment groups to agree with the statement that "science is fun," suggesting that organ dissections may promote positive attitudes toward science. The findings of this study provide evidence for the importance of multiple types of hands-on activities in anatomy laboratory courses.

  7. Effective treatment strategies against Ebola virus

    Directory of Open Access Journals (Sweden)

    Amina Yaqoob

    2015-08-01

    Full Text Available Ebola virus (EBOV, a member of order Mononegavirales is most famous for causing the endemics of hemorrhagic fever in different countries of the world. Various effective treatment for EBOV are available presently but different clinical trials and experimental studies on animal models are ongoing for this purpose. Results from different studies showed that selective vaccines and therapeutic drugs have potential to interfere the viral life events within host cell in order to inhibit its replication. Various pre-clinical trials in this regard are proved successful on non-human primates (NHPs and found to be significant in inhibiting EBOV infections. It is the need of hour to develop effective vaccines against Ebola virus to combat this problem as soon as possible. The present article is a brief review on potential treatment strategies against Ebola virus.

  8. Residual stress and its effect on the mechanical properties of Y-doped Mg alloy fabricated via back-pressure assisted equal channel angular pressing (ECAP-BP)

    Czech Academy of Sciences Publication Activity Database

    Shen, J.; Gärtnerová, Viera; Kecskes, L.J.; Kondoh, K.; Jäger, Aleš; Wei, Q.

    2016-01-01

    Roč. 669, Jul (2016), s. 110-117 ISSN 0921-5093 R&D Projects: GA ČR GBP108/12/G043 Institutional support: RVO:68378271 Keywords : magnesium * equal channel angular pressing * ECAP * rare earth Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 3.094, year: 2016

  9. Equality in Sport for Women.

    Science.gov (United States)

    Geadelmann, Patricia L.; And Others

    The subject of equal rights and opportunities for women in the field of physical education is discussed in nine articles. The major emphasis is on the legal aspects of sex discrimination. Defining equality, knowing the laws regarding enforcement, understanding the court procedures, and realizing the avenues for change are the essential tools…

  10. Governing Equality: Mathematics for All?

    Science.gov (United States)

    Diaz, Jennifer D.

    2013-01-01

    With the notion of governmentality, this article considers how the equal sign (=) in the U.S. math curriculum organizes knowledge of equality and inscribes cultural rules for thinking, acting, and seeing in the world. Situating the discussion within contemporary math reforms aimed at teaching mathematics for all, I draw attention to how the…

  11. Luck, Choice, and Educational Equality

    Science.gov (United States)

    Calvert, John

    2015-01-01

    Harry Brighouse discusses two conceptions of educational equality. The first is a type of equality of opportunity, heavily influenced by the work of John Rawls, which he calls the meritocratic conception. According to this conception, an individual's educational prospects should not be influenced by factors such as their social class background.…

  12. Turbo Equalization for Digital Coherent Receivers

    DEFF Research Database (Denmark)

    Arlunno, Valeria; Caballero Jambrina, Antonio; Borkowski, Robert

    2014-01-01

    . In this paper, it is demonstrated that Turbo Equalization routines can be used to mitigate performance degradations stemming from optical fiber propagation effects both in optical fiber dispersion managed and unmanaged coherent detection links. The effectiveness of this solution is analyzed both numerically...

  13. An Analysis of Citizenship and Democracy Education Text Book in the Context of Gender Equality and Determining Students' Perceptions on Gender Equality

    Science.gov (United States)

    Kalayci, Nurdan; Hayirsever, Fahriye

    2014-01-01

    Gender equality has been explained as both the equal treatment of women and men before the law and women's and men's equal usage of resources, opportunities, and services within the family and society. Today, although the conditions that support gender inequality have relatively decreased, gender discrimination still persists. Gender equality is…

  14. Psoriasis: characteristics, psychosocial effects and treatment options.

    LENUS (Irish Health Repository)

    Ryan, Sheila

    2012-02-01

    Psoriasis is a complex chronic non-infectious inflammatory skin disease with a variety of different presentations. The classic presentation is of well-defined red plaques with silver scale. The characteristic scale makes the disorder highly visible and intrusive on the patient\\'s lifestyle. The visible nature of the disease ensures that psoriasis has both physical and psychosocial effects. In normal skin, epidermal cell reproduction and proliferation takes 28 days. In psoriasis this process is considerably accelerated to approximately 4 days, resulting in the deposit of immature cells on the skin. While the exact cause of this process is unknown, certain environmental and genetic factors are known to be triggers. Disease management depends on disease severity, psychosocial effects and the patient\\'s lifestyle. To effectively treat this disease the nurse must be skilled in psoriasis management, and in patient education and motivation. This article reviews the characteristics, aetiology, psychosocial effects and treatment strategies of psoriasis.

  15. Interaction Effects between Exposure to Sexually Explicit Online Materials and Individual, Family, and Extrafamilial Factors on Hong Kong High School Students' Beliefs about Gender Role Equality and Body-Centered Sexuality

    Science.gov (United States)

    To, Siu-ming; Kan, Siu-mee Iu; Ngai, Steven Sek-yum

    2015-01-01

    This study examined the interaction effects between Hong Kong adolescents' exposure to sexually explicit online materials (SEOM) and individual, family, peer, and cultural factors on their beliefs about gender role equality and body-centered sexuality. Based on a survey design with a sample of 503 high school students in Hong Kong, the results…

  16. Resistance Training with Single vs. Multi-joint Exercises at Equal Total Load Volume: Effects on Body Composition, Cardiorespiratory Fitness, and Muscle Strength

    Directory of Open Access Journals (Sweden)

    Antonio Paoli

    2017-12-01

    Full Text Available The present study aimed to compare the effects of equal-volume resistance training performed with single-joint (SJ or multi-joint exercises (MJ on VO2max, muscle strength and body composition in physically active males. Thirty-six participants were divided in two groups: SJ group (n = 18, 182.1 ± 5.2, 80.03 ± 2.78 kg, 23.5 ± 2.7 years exercised with only SJ exercises (e.g., dumbbell fly, knee extension, etc. and MJ group (n = 18, 185.3 ± 3.6 cm, 80.69 ± 2.98 kg, 25.5 ± 3.8 years with only MJ exercises (e.g., bench press, squat, etc.. The total work volume (repetitions × sets × load was equated between groups. Training was performed three times a week for 8 weeks. Before and after the training period, participants were tested for VO2max, body composition, 1 RM on the bench press, knee extension and squat. Analysis of covariance (ANCOVA was used to compare post training values between groups, using baseline values as covariates. According to the results, both groups decreased body fat and increased fat free mass with no difference between them. Whilst both groups significantly increased cardiorespiratory fitness and maximal strength, the improvements in MJ group were higher than for SJ in VO2max (5.1 and 12.5% for SJ and MJ, bench press 1 RM (8.1 and 10.9% for SJ and MJ, knee extension 1 RM (12.4 and 18.9% for SJ and MJ and squat 1 RM (8.3 and 13.8% for SJ and MJ. In conclusion, when total work volume was equated, RT programs involving MJ exercises appear to be more efficient for improving muscle strength and maximal oxygen consumption than programs involving SJ exercises, but no differences were found for body composition.

  17. Equal opportunities group. His mission : accelerating equal opportunities at CERN

    CERN Multimedia

    Patrice Loïez

    2000-01-01

    L. to r.: Michel Mayoud, Christine Petit-Jean-Genaz, the Equal Opportunities Officer Sudeshna Datta-Cockerill, Elena Wildner, Anne-Sylvie Cerne, Karl-Heinz Kissler, the Chairman John Ellis and Eva-Maria Groniger-Voss

  18. Equal pay by gender and by nationality: a comparative analysis of Switzerland's unequal equal pay policy regimes across time

    OpenAIRE

    Erne, Roland; Imboden, Natalie

    2017-01-01

    What explains the adoption of two different policies on equal pay by gender (EPG) and by nationality (EPN) in Switzerland? And why is the liberal, litigation-based, equal pay policy regime set up by the Gender Equality Act of 1996 much less effective than the neocorporatist ‘accompanying measures’ to the Bilateral European Union–Switzerland Agreement on Free Movement of Persons adopted in 1999 to ensure equal pay for workers of different national origins? The formation of two different policy...

  19. Equal Pay for Equal Work in Academic Obstetrics and Gynecology.

    Science.gov (United States)

    Eichelberger, Kacey Y

    2018-02-01

    The most compelling data suggest women in academic obstetrics and gynecology earn approximately $36,000 less than male colleagues per year in regression models correcting for commonly cited explanatory variables. Although residual confounding may exist, academic departments in the United States should consider rigorous examination of their own internal metrics around salary to ensure gender-neutral compensation, commonly referred to as equal pay for equal work.

  20. Evaluation of treatment effects by ranking

    DEFF Research Database (Denmark)

    Halekoh, U; Kristensen, K

    2008-01-01

    In crop experiments measurements are often made by a judge evaluating the crops' conditions after treatment. In the present paper an analysis is proposed for experiments where plots of crops treated differently are mutually ranked. In the experimental layout the crops are treated on consecutive...... plots usually placed side by side in one or more rows. In the proposed method a judge ranks several neighbouring plots, say three, by ranking them from best to worst. For the next observation the judge moves on by no more than two plots, such that up to two plots will be re-evaluated again...... in a comparison with the new plot(s). Data from studies using this set-up were analysed by a Thurstonian random utility model, which assumed that the judge's rankings were obtained by comparing latent continuous utilities or treatment effects. For the latent utilities a variance component model was considered...

  1. PROMOTING GENDER EQUALITY TROUGH EQUAL LIFE STANDARD IN EU COUNTRIES

    Directory of Open Access Journals (Sweden)

    Aleksandar Dashtevski

    2018-06-01

    Full Text Available After the World War II, especially in the early fifties there is an expansion of gender rights. Women are massively employed all over the world in all sectors of social life, contributing to an increase in both their own standard of living and the standard in their own countries. As the importance and role of women grows, this is achieved with increasing respect for its rights. Gender means elimination of inequality and promote equality between women and men in all areas of social life. If we want to achieve gender equality as a whole, it is inevitable to achieve an economic consolidation of the two sexes. Economic strengthening is possible trough equal pay. Experience shows that payments are not equal when it comes to wages for men and women. Therefore, the EU is constantly working to regulate this area, with special regulations, which are mandatory for the member states, but should also be respected by countries that would like to join the union. This led to the promotion of gender equality through an equal life.

  2. CNS effects following the treatment of malignancy

    International Nuclear Information System (INIS)

    Rane, N.; Quaghebeur, G.

    2012-01-01

    Corporeal and central nervous system (CNS) axis chemotherapy and radiotherapy have long been used for the effective treatment and prophylaxis of CNS, body malignancies, and leukaemias. However, they are not without their problems. Following the proliferation of magnetic resonance neuroimaging in recent years it has become clear that the spectrum of toxicity that these therapies produce ranges from subclinical white matter changes to overt brain necrosis. The effects are both direct and indirect and via different pathological mechanisms. Chronic and progressive changes can be detected many years after the initial intervention. In addition to leucoencephalopathic changes, grey matter changes are now well described. Changes may be difficult to distinguish from tumour recurrence, though may be reversible and remediable, and are thus very important to differentiate. In this review toxic effects are classified and their imaging appearances discussed, with reference to specific syndromes.

  3. The effect of high hydrostatic pressure on creep behaviour of pure Al and a Cu-0.2 wt% Zr alloy processed by equal-channel angular pressing

    Czech Academy of Sciences Publication Activity Database

    Dvořák, Jiří; Sklenička, Václav; Betekhtin, V. I.; Kadomtsev, A. G.; Král, Petr; Kvapilová, Marie; Svoboda, Milan

    2013-01-01

    Roč. 584, NOV (2013), s. 103-113 ISSN 0921-5093 R&D Projects: GA ČR(CZ) GAP108/11/2260; GA MŠk(CZ) ED1.1.00/02.0068 Institutional support: RVO:68081723 Keywords : Equal-channel angular processing * Nanostructured materials * Mechanical characterization * Electron microscopy * Grain boundaries Subject RIV: JG - Metallurgy Impact factor: 2.409, year: 2013

  4. Certifying Equality With Limited Interaction

    DEFF Research Database (Denmark)

    Brody, Joshua Eric; Chakrabarti, Amit; McGregor, Andrew

    2012-01-01

    The \\textsc{equality} problem is usually one's first encounter with communication complexity and is one of the most fundamental problems in the field. Although its deterministic and randomized communication complexity were settled decades ago, we find several new things to say about the problem...... cost bounds, we obtain new bounded-round randomized lower bounds for the \\textsc{or-equality} problem that have a direct-sum flavor. Such lower bounds were previously known only for deterministic protocols or one-round randomized protocols. The \\textsc{or-equality} problem is in turn closely related...

  5. A Cost-Effectiveness Analysis of Seminatural Wetlands and Activated Sludge Wastewater-Treatment Systems

    Science.gov (United States)

    Mannino, Ilda; Franco, Daniel; Piccioni, Enrico; Favero, Laura; Mattiuzzo, Erika; Zanetto, Gabriele

    2008-01-01

    A cost-effectiveness analysis was performed to evaluate the competitiveness of seminatural Free Water Surface (FWS) wetlands compared to traditional wastewater-treatment plants. Six scenarios of the service costs of three FWS wetlands and three different wastewater-treatment plants based on active sludge processes were compared. The six scenarios were all equally effective in their wastewater-treatment capacity. The service costs were estimated using real accounting data from an experimental wetland and by means of a market survey. Some assumptions had to be made to perform the analysis. A reference wastewater situation was established to solve the problem of the different levels of dilution that characterize the inflow water of the different systems; the land purchase cost was excluded from the analysis, considering the use of public land as shared social services, and an equal life span for both seminatural and traditional wastewater-treatment plants was set. The results suggest that seminatural systems are competitive with traditional biotechnological systems, with an average service cost improvement of 2.1-fold to 8-fold, according to the specific solution and discount rate. The main improvement factor was the lower maintenance cost of the seminatural systems, due to the self-regulating, low artificial energy inputs and the absence of waste to be disposed. In this work, only the waste-treatment capacity of wetlands was considered as a parameter for the economic competitiveness analysis. Other goods/services and environmental benefits provided by FWS wetlands were not considered.

  6. Curative effect of moisturizing eye decoction combined with artificial tears in treatment on ophthalmoxerosis

    Directory of Open Access Journals (Sweden)

    Yu-Ping Ren

    2017-08-01

    Full Text Available AIM: To observe the clinical effects of moisturizing eye decoction combined with artificial tears in the treatment of ophthalmoxerosis.METHODS: A randomized controlled clinical research method was employed. One hundred-sixty patients diagnosed with ophthalmoxerosis were equally divided into a treatment group and a control group. In the treatment group, patients were given one dose per day of the moisturizing eye decoction as well as artificial tear drops three times a day. The patients in the control group were treated with artificial tears drops three times a day. The course of treatment was 3mo. Dry-eye symptoms, tear break-up time(BUTby the slit lamp, the time of tear secretion(Schirmers Ⅰ test, corneal fluorescein staining(FL, and curative effects were observed before treatment as well as in the first and third months after treatment.RESULTS: There were no significant differences between the two groups in terms of BUT, SⅠt, and FL before treatment(P>0.05. After treatment in the first and the third months, the BUT, SⅠt, FL, and curative effects were significantly different between the two groups(PCONCLUSION: Moisturizing eye decoction combined with artificial tears in the treatment of ophthalmoxerosis can improve efficacy.

  7. Non-equal-time Poisson brackets

    OpenAIRE

    Nikolic, H.

    1998-01-01

    The standard definition of the Poisson brackets is generalized to the non-equal-time Poisson brackets. Their relationship to the equal-time Poisson brackets, as well as to the equal- and non-equal-time commutators, is discussed.

  8. The Nordic Gender Equality Model

    OpenAIRE

    Teigen, Mari; Skjeie, Hege

    2017-01-01

    In this chapter, we investigate the descriptive premises involved in portrayals of a Nordic model of gender equality. Mainly, we focus on the equality dimensions that form the baseline in comparative welfare state research and research on political participation. We outline these dimensions as norms for economic equity and democratic parity. First, we examine whether and how descriptive statistics that assess these two dimensions currently rank Nordic countries compared with other European co...

  9. The Paradox of Equal Opportunities

    Directory of Open Access Journals (Sweden)

    Mitja Sardoč

    2014-06-01

    Full Text Available The basic assumption of the idea of equal opportunities is based on the assertion that all individuals competing for an advantaged social position should have equal opportunities, i.e., that each and every one of them should have fair opportunities to achieve a particular goal. Despite the fact that equal opportunities is one of the basic mechanisms for a just distribution of advantageous social positions, the idea of fair equality of opportunity remains divided between different competing political projects, e.g., egalitarian liberalism, libertarian political theory, multiculturalism, etc. This paper examines two basic dimensions of equal opportunities to which existing conceptions fail to offer a unanimous answer, i.e., a the issue of fairness and b the issue of the currency of fairness. The concluding part of this paper presents two basic paradoxes that determine both the direction of the discussion as well as the possible solutions to the achievement of fair equal opportunities as part of any process for competing for advantageous social positions.

  10. Incentives, health promotion and equality.

    Science.gov (United States)

    Voigt, Kristin

    2012-07-01

    The use of incentives to encourage individuals to adopt 'healthier' behaviours is an increasingly popular instrument in health policy. Much of the literature has been critical of 'negative' incentives, often due to concerns about equality; 'positive' incentives, however, have largely been welcomed as an instrument for the improvement of population health and possibly the reduction of health inequalities. The aim of this paper is to provide a more systematic assessment of the use of incentives from the perspective of equality. The paper begins with an overview of existing and proposed incentive schemes. I then suggest that the distinction between 'positive' and 'negative' incentives - or 'carrots' and 'sticks' - is of limited use in distinguishing those incentive schemes that raise concerns of equality from those that do not. The paper assesses incentive schemes with respect to two important considerations of equality: equality of access and equality of outcomes. While our assessment of incentive schemes will, ultimately, depend on various empirical facts, the paper aims to advance the debate by identifying some of the empirical questions we need to ask. The paper concludes by considering a number of trade-offs and caveats relevant to the assessment of incentive schemes.

  11. [Silvicultural treatments and their selection effects].

    Science.gov (United States)

    Vincent, G

    1973-01-01

    Selection can be defined in terms of its observable consequences as the non random differential reproduction of genotypes (Lerner 1958). In the forest stands we are selecting during the improvements-fellings and reproduction treatments the individuals surpassing in growth or in production of first-class timber. However the silvicultural treatments taken in forest stands guarantee a permanent increase of forest production only in such cases, if they have been taken with respect to the principles of directional (dynamic) selection. These principles require that the trees determined for further growing and for forest regeneration are selected by their hereditary properties, i.e. by their genotypes.For making this selection feasible, our study deals with the genetic parameters and gives some examples of the application of the response, the selection differential, the heritability in the narrow and in the broad sense, as well as of the genetic and genotypic gain. On the strength of this parameter we have the possibility to estimate the economic success of several silvicultural treatments in forest stands.The mentioned examples demonstrate that the selection measures of a higher intensity will be manifested in a higher selection differential, in a higher genetic and genotypic gain and that the mentioned measures show more distinct effects in the variable populations - in natural forest - than in the population characteristic by a smaller variability, e.g. in many uniform artificially established stands.The examples of influences of different selection on the genotypes composition of population prove that genetics instructs us to differentiate the different genotypes of the same species and gives us at the same time a new criterions for evaluating selectional treatments. These criterions from economic point of view is necessary to consider in silviculture as advantageous even for the reason that we can judge from these criterions the genetical composition of forest stands

  12. Domestic gender equality and childbearing in Sweden

    Directory of Open Access Journals (Sweden)

    Frances Goldscheider

    2013-12-01

    Full Text Available Background: Sweden, which is among the most gender-equal societies in the world, combines 'modern' family patterns such as unmarried cohabitation, delayed parenthood, high maternal labor force participation, and high break-up rates - all usually linked with low birth rates - with relatively high fertility. Sweden also has a high level of shared parental responsibility for home and children. Objective: After decades of late 20th century research showing that increasing gender equality in the workplace was linked with lower fertility, might gender equality in the home increase fertility? Methods: Using data from the Swedish Young Adult Panel Study (YAPS, we use Cox regression to examine the effects on first, second, and third births of 1 holding attitudes about sharing equally in the care of the home and children, and 2 actual sharing in these domestic tasks. Results: Our analysis shows that, measuring attitudes before the transition to parenthood and actual practice four years later, it is inconsistency between sharing attitudes and the actual division of housework that reduces the likelihood of continued childbearing, especially on second births among women. Conclusions: As women are most likely to confront an inconsistent situation, with egalitarian ideals in a household without equal sharing, it is clear that having a partner who does not share housework is depressing Swedish fertility.

  13. Gender Equality Policies and Higher Education Careers

    Science.gov (United States)

    Berggren, Caroline

    2011-01-01

    Gender equality policies regulate the Swedish labour market, including higher education. This study analyses and discusses the career development of postgraduate students in the light of labour market influences. The principle of gender separation is used to understand these effects. Swedish register data encompassing information on 585…

  14. Leaky Zero-Forcing Adaptive Equalization

    NARCIS (Netherlands)

    Bergmans, J.W.M.; Lin, M.Y.

    2004-01-01

    Zero-forcing equalizer adaptation schemes are attractive because of their simplicity. We study their steady-state solution, and find that it is more poorly conditioned than that of least mean-square adaptation schemes. A simple yet effective solution to this problem, based on tap leakage, is

  15. Channel Equalization Using Multilayer Perceptron Networks

    Directory of Open Access Journals (Sweden)

    Saba Baloch

    2012-07-01

    Full Text Available In most digital communication systems, bandwidth limited channel along with multipath propagation causes ISI (Inter Symbol Interference to occur. This phenomenon causes distortion of the given transmitted symbol due to other transmitted symbols. With the help of equalization ISI can be reduced. This paper presents a solution to the ISI problem by performing blind equalization using ANN (Artificial Neural Networks. The simulated network is a multilayer feedforward Perceptron ANN, which has been trained by utilizing the error back-propagation algorithm. The weights of the network are updated in accordance with training of the network. This paper presents a very effective method for blind channel equalization, being more efficient than the pre-existing algorithms. The obtained results show a visible reduction in the noise content.

  16. TROUBLING GENDER EQUALITY: REVISITING GENDER EQUALITY WORK IN THE FAMOUS NORDIC MODEL COUNTRIES

    Directory of Open Access Journals (Sweden)

    Charlotta Edström

    2016-06-01

    Full Text Available This article concerns gender equality work, that is, those educational and workplace activities that involve the promotion of gender equality. It is based on research conducted in Sweden and Finland, and focuses on the period during which the public sector has become more market-oriented and project-based all over the Nordic countries. The consequences of this development on gender equality work have not yet been thoroughly analysed. Our joint empirical analysis is based on discourse-analytic methodology and two previous empirical studies. By analysing interviews conducted with people involved in gender equality work, this article emphasises the effects of market-oriented and project-based gender equality work in education and working life in Sweden and in Finland. The findings highlight an alliance between projectisation and heteronormativity that acts to regulate how gender equality ought to be talked about in order for its issues to be heard. A persistently constructed ‘remedy’ to ‘the gender equality problem’ is that girls and women are positioned as ‘needing’ to change more than boys and men, by adopting more traditionally ‘masculine manners’ and choosing to work in more ‘masculine sectors’. The findings also show that the constitutive forces of these discourses provide little leeway for critical perspectives.

  17. 40 CFR 35.935-6 - Equal employment opportunity.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Equal employment opportunity. 35.935-6 Section 35.935-6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act § 35.935-6 Equal employment opportunity. Contracts...

  18. The perceptions of students on gender equality | Nkosi | Gender and ...

    African Journals Online (AJOL)

    The study is about the perceptions of University of Venda students regarding gender equality. South Africa has made significant strides in relation to gender mainstreaming. In addition to the constitution, there are many policies that have been developed and adopted to ensure fair and equal treatment of women. However ...

  19. Improved nonhuman animal welfare is related more to income equality than it is to income.

    Science.gov (United States)

    Morris, Michael C

    2013-01-01

    The link between nonhuman animal welfare, income, and income inequality (Gini coefficient) was tested using consumption of animal products, laws protecting animals on the farm from the worst abuses, and animals used in experimentation as indicators. Experimentation on all animals and on rodents significantly increased in high-income European countries, although there was some evidence that the increase in experimentation on cats and dogs started to flatten out for the highest income countries. Consumption of all flesh products in high-income countries declined in more equal societies. More equal high-income countries also had stricter regulations protecting animals, although the same correlation was not seen between U.S. states. In New Zealand, there was some evidence that testing on cats and dogs declined during years when equality was improving. The results provide little evidence for a Kuznets effect of income on animal welfare, with the possible exception of companion animal treatment. They do, however, suggest that greater equality can be a predictor for better treatment of animals. Previous research has strongly suggested that social conditions for humans improve with greater equality. The same may be true for nonhuman animals. Alternatively, conditions conducive to improving human income equality may also lead to better animal welfare outcomes.

  20. Preconditioning by light-load eccentric exercise is equally effective as low-level laser therapy in attenuating exercise-induced muscle damage in collegiate men

    Directory of Open Access Journals (Sweden)

    Nausheen S

    2017-09-01

    similar protection over time.Conclusion: This study indicated that light-load eccentric exercise confers similar protective effect against subsequent maximal eccentric exercise as LLLT. Both the treatments could be used reciprocally based on the patient preference, costs, and feasibility of the equipment. Keywords: delayed onset muscle soreness, isometric strength, elbow flexors, repeated bout effect, lactate dehydrogenase, creatine kinase

  1. The fallacy of "equal treatment" in Brazil's bill of rights for internet users A falácia da "igualdade de tratamento" na carta brasileira de direitos dos usuários da internet

    Directory of Open Access Journals (Sweden)

    J. Gregory Sidak

    2012-12-01

    Full Text Available The "Brazilian bill of rights for internet users," or "marco civil," has been under consideration at the brazilian congress since 2011. Marco civil's provisions for network neutrality have been particularly controversial. Proponents of network neutrality in Brazil advocate for the "equal treatment" of all data packets, including banning internet service providers from offering to content providers the option to purchase enhanced quality of service in the delivery of data packets. These network neutrality rules conflict with the other goals and principles of marco civil-particularly goals to promote internet access, to foster innovation, and to protect the constitutional right of freedom of speech and the free flow of information.A "carta Brasileira de direitos dos usuários da internet," ou "marco civil," tramita no congresso Brasileiro desde 2011. As disposições do marco civil relativas à neutralidade de rede são particularmente controversas. Os defensores da neutralidade de rede no Brasil advogam pela "igualdade de tratamento" de todos os pacotes de dados, inclusive proibindo que provedores de serviço de acesso à internet ofereçam aos provedores de conteúdo a opção de adquirir uma melhor qualidade de serviço na entrega de pacotes de dados. Essas disposições relativas à neutralidade de rede conflitam com outros objetivos e princípios do marco civil - especialmente os objetivos de promover o acesso à internet, promover a inovação, e garantir o direito constitucional de liberdade de expressão e informação.

  2. Drug Repositioning for Effective Prostate Cancer Treatment.

    Science.gov (United States)

    Turanli, Beste; Grøtli, Morten; Boren, Jan; Nielsen, Jens; Uhlen, Mathias; Arga, Kazim Y; Mardinoglu, Adil

    2018-01-01

    Drug repositioning has gained attention from both academia and pharmaceutical companies as an auxiliary process to conventional drug discovery. Chemotherapeutic agents have notorious adverse effects that drastically reduce the life quality of cancer patients so drug repositioning is a promising strategy to identify non-cancer drugs which have anti-cancer activity as well as tolerable adverse effects for human health. There are various strategies for discovery and validation of repurposed drugs. In this review, 25 repurposed drug candidates are presented as result of different strategies, 15 of which are already under clinical investigation for treatment of prostate cancer (PCa). To date, zoledronic acid is the only repurposed, clinically used, and approved non-cancer drug for PCa. Anti-cancer activities of existing drugs presented in this review cover diverse and also known mechanisms such as inhibition of mTOR and VEGFR2 signaling, inhibition of PI3K/Akt signaling, COX and selective COX-2 inhibition, NF-κB inhibition, Wnt/β-Catenin pathway inhibition, DNMT1 inhibition, and GSK-3β inhibition. In addition to monotherapy option, combination therapy with current anti-cancer drugs may also increase drug efficacy and reduce adverse effects. Thus, drug repositioning may become a key approach for drug discovery in terms of time- and cost-efficiency comparing to conventional drug discovery and development process.

  3. Analytical treatment of the runaway-effect

    International Nuclear Information System (INIS)

    Kaeppeler, H.J.

    1980-09-01

    In the analytical treatment of the runaway-effect there appear the integrals Isub(m)(α). For m = 1, 2 and 3, series expansions for these integrals can be found in the literature. Furthermore, asymptotic solutions for Isub(m)(α) are known. It is shown here that the solutions for Isub(m)(α) can be approximated by the modified Bessel Function Ksub(n)(αsup(ν)) in such a way that for α → 0 the exact limiting value for Isub(m)(α) follows and that for α → infinite essentially the known asymptotic solutions for Isub(m)(α) follow. The maximum error for this approximation in the order of percent is considered justifiable for the application considered. (orig.)

  4. Perceptions of gender equality and attitudes toward equal ...

    African Journals Online (AJOL)

    The aim of this study was to explain consciousness of gender inequality in school sport and predict pro-equality attitudes among 1580 respondents (934 girls and 646 boys) from 45 Botswana secondary schools. Results of separate multiple regression models indicate that girls' sport participation is negatively correlated with ...

  5. Distributive Equality, Relational Equality and Preferences about Higher Education

    Science.gov (United States)

    Voigt, Kristin

    2017-01-01

    Are scenarios in which disadvantaged students prefer not to attend (certain) universities a concern from the perspective of an egalitarian theory of justice? I consider this question from the respective perspectives of two prominent approaches to equality: distributive theories, which focus on the fairness of inequalities in outcomes, and…

  6. Oesophageal heat exchangers with a diameter of 11mm or 14.7mm are equally effective and safe for targeted temperature management.

    Directory of Open Access Journals (Sweden)

    Daniel C Schroeder

    Full Text Available Targeted temperature management (TTM is widely used in critical care settings for conditions including hepatic encephalopathy, hypoxic ischemic encephalopathy, meningitis, myocardial infarction, paediatric cardiac arrest, spinal cord injury, traumatic brain injury, ischemic stroke and sepsis. Furthermore, TTM is a key treatment for patients after out-of-hospital cardiac-arrest (OHCA. However, the optimal cooling method, which is quick, safe and cost-effective still remains controversial. Since the oesophagus is adjacent to heart and aorta, fast heat-convection to the central blood-stream could be achieved with a minimally invasive oesophageal heat exchanger (OHE. To date, the optimal diameter of an OHE is still unknown. While larger diameters may cause thermal- or pressure-related tissue damage after long-term exposure to the oesophageal wall, smaller diameter (e.g., gastric tubes, up to 11mm may not provide effective cooling rates. Thus, the objective of the study was to compare OHE-diameters of 11mm (OHE11 and 14.7mm (OHE14.7 and their effects on tissue and cooling capability.Pigs were randomized to OHE11 (N = 8 or OHE14.7 (N = 8. After cooling, pigs were maintained at 33°C for 1 hour. After 10h rewarming, oesophagi were analyzed by means of histopathology. The oesophagus of four animals from a separate study that underwent exactly the identical preparation and cooling protocol described above but received a maintenance period of 24h were used as histopathological controls.Mean cooling rates were 2.8±0.4°C°C/h (OHE11 and 3.0±0.3°C °C/h (OHE14.7; p = 0.20. Occasional mild acute inflammatory transepithelial infiltrates were found in the cranial segment of the oesophagus in all groups including controls. Deviations from target temperature were 0.1±0.4°C (OHE11 and 0±0.1°C (OHE14.7; p = 0.91. Rewarming rates were 0.19±0.07°C °C/h (OHE11 and 0.20±0.05°C °C/h (OHE14.7; p = 0.75.OHE with diameters of 11 mm and 14.7 mm achieve

  7. Are all first-generation antipsychotics equally effective in treating schizophrenia? A meta-analysis of randomised, haloperidol-controlled trials.

    Science.gov (United States)

    Dold, Markus; Tardy, Magdolna; Samara, Myrto T; Li, Chunbo; Kasper, Siegfried; Leucht, Stefan

    2016-04-01

    Narrative, unsystematic reviews revealed no differences in efficacy between the various first-generation antipsychotics (FGAs) resulting in the psychopharmacological assumption of comparable efficacy between the different FGAs. We sought to determine if the assumption of comparable efficacy of all FGAs can be regarded as evidence-based using meta-analytic statistics. A systematic literature survey (Cochrane Schizophrenia Group trial register) was applied to identify all RCTs that compared oral haloperidol with another oral FGA in schizophrenia. Primary outcome was dichotomous treatment response. Secondary outcomes were symptom severity measured by rating scales, discontinuation rates, and specific adverse effects. Altogether, 79 RCTs with 4343 participants published between 1962 and 1999 were included. We found a significant between-group difference only between haloperidol and nemonapride, but not for the remaining 19 investigated FGAs. There were no significant differences for discontinuation rates. As most of the single meta-analytic comparisons can be regarded as underpowered, the evidence for the assumption of comparable efficacy of all FGAs is inconclusive. We therefore cannot confirm or reject the statements of previous narrative, unsystematic reviews in this regard. Our findings were limited by the small sample size in the individual comparisons and the low methodological quality in many included studies.

  8. Democracy, property rights, income equality, and corruption

    OpenAIRE

    Dong, Bin; Torgler, Benno

    2011-01-01

    This paper presents theoretical and empirical evidence on the nexus between corruption and democracy. We establish a political economy model where the effect of democracy on corruption is conditional on income distribution and property rights protection. Our empirical analysis with cross-national panel data provides evidence that is consistent with the theoretical prediction. Moreover, the effect of democratization on corruption depends on the protection of property rights and income equality...

  9. Women, gender equality, and diabetes.

    Science.gov (United States)

    Hannan, Carolyn

    2009-03-01

    Discussion of women, gender equality, and diabetes should be placed in the context of United Nations mandates on women's health which highlight the need for equal access to information, prevention activities, services, and care across the life cycle. Gender differences and inequalities have been identified in relation to causes and consequences of diabetes and access to services and support between women and men, and among different groups of women. Appropriate gender-sensitive policy responses, including research and data collection, need to be developed. The recent United Nations resolution on diabetes provides an opportunity to strengthen the focus on women and diabetes.

  10. Late effects after treatment for Hodgkin lymphoma

    NARCIS (Netherlands)

    Daniëls, Laurien Aletta

    2014-01-01

    Although modern treatment strategies have made Hodgkin Lymphoma (HL) a highly curable disease, there is a life-long increased risk of morbidity and mortality due to treatment. Over time it has become increasingly evident that the historically used extensive treatment fields can potentially lead to

  11. STEM Equality and Diversity Toolkit

    Science.gov (United States)

    Collins, Jill

    2011-01-01

    In 2008, the Centre for Science Education at Sheffield Hallam University teamed up with VT Enterprise (now Babcock International) in their submission of a successful bid to deliver the national STEM (Science, Technology, Engineering and Maths) Subject Choice and Careers Project. An integral part of the bid was the promotion of equality and…

  12. Equal Potential: A Collective Fraud.

    Science.gov (United States)

    Gottfredson, Linda S.

    2000-01-01

    Critiques the College Board's report, "Reaching the Top," asserting that it illustrates collective fraud in the social sciences, which sustains an egalitarian fiction that intelligence is clustered equally across all human populations. Suggests that while the report omits certain popular falsehoods, it also omits crucial truths about…

  13. Equalizing Teachers' Pay in Louisiana

    Science.gov (United States)

    Cassimere, Raphael Jr.

    1977-01-01

    Suggests that the struggle for teacher salary equalization in Louisiana ended in success, but it was one chapter in a long struggle to gain the full citizenship that black teachers and their pupils dreamed would one day be theirs. (Author/AM)

  14. Equalization equations in reactant resolution

    Indian Academy of Sciences (India)

    Unknown

    given partitioning of the system in physical or functional space. The most frequently ... Then, the inter-reactant equilibrium is considered. The ... Global equilibrium. Even though the chemical potential in the case of global equilibrium is equalized by definition (see (1)), we repeat here the proof, for the current needs, using.

  15. Omalizumab Is Equally Effective in Persistent Allergic Oral Corticosteroid-Dependent Asthma Caused by Either Seasonal or Perennial Allergens: A Pilot Study.

    Science.gov (United States)

    Domingo, Christian; Pomares, Xavier; Navarro, Albert; Rudi, Núria; Sogo, Ana; Dávila, Ignacio; Mirapeix, Rosa M

    2017-02-28

    Omalizumab is marketed for chronic severe asthma patients who are allergic to perennial allergens. Our purpose was to investigate whether omalizumab is also effective in persistent severe asthma due to seasonal allergens. Thirty patients with oral corticosteroid-dependent asthma were treated with Omalizumab according to the dosing table. For each patient with asthma due to seasonal allergens, we recruited the next two consecutive patients with asthma due to perennial allergens. The dose of oral methyl prednisolone was tapered at a rate of 2 mg every two weeks after the start of treatment with omalizumab depending on tolerance. At each monthly visit, a forced spirometry and fractional exhaled nitric oxide (FeNO) measurement were performed and the accumulated monthly methyl prednisolone dose was calculated. At entry, there were no differences between groups in terms of gender, body mass index or obesity, year exacerbation rate, monthly dose of methyl-prednisolone (MP), FeNO and blood immunoglobuline E (IgE) MP, FeNO and IgE values, or spirometry (perennial: FVC: 76%; FEV₁: 62%; seasonal: FVC: 79%; FEV₁: 70%). The follow-up lasted 76 weeks. One patient in each group was considered a non-responder. Spirometry did not worsen in either group. There was a significant intragroup reduction in annual exacerbation rate and methyl prednisolone consumption but no differences were detected in the intergroup comparison. Omalizumab offered the same clinical benefits in the two cohorts regardless of whether the asthma was caused by a seasonal or a perennial allergen. These results strongly suggest that allergens are the trigger in chronic asthma but that it is the persistent exposure to IgE that causes the chronicity.

  16. Omalizumab Is Equally Effective in Persistent Allergic Oral Corticosteroid-Dependent Asthma Caused by Either Seasonal or Perennial Allergens: A Pilot Study

    Directory of Open Access Journals (Sweden)

    Christian Domingo

    2017-02-01

    Full Text Available Omalizumab is marketed for chronic severe asthma patients who are allergic to perennial allergens. Our purpose was to investigate whether omalizumab is also effective in persistent severe asthma due to seasonal allergens. Thirty patients with oral corticosteroid-dependent asthma were treated with Omalizumab according to the dosing table. For each patient with asthma due to seasonal allergens, we recruited the next two consecutive patients with asthma due to perennial allergens. The dose of oral methyl prednisolone (MP was tapered at a rate of 2 mg every two weeks after the start of treatment with omalizumab depending on tolerance. At each monthly visit, a forced spirometry and fractional exhaled nitric oxide (FeNO measurement were performed and the accumulated monthly MP dose was calculated. At entry, there were no differences between groups in terms of gender, body mass index or obesity, year exacerbation rate, monthly dose of MP, FeNO and blood immunoglobuline E (IgE values, or spirometry (perennial: FVC: 76%; FEV1: 62%; seasonal: FVC: 79%; FEV1: 70%. The follow-up lasted 76 weeks. One patient in each group was considered a non-responder. Spirometry did not worsen in either group. There was a significant intragroup reduction in annual exacerbation rate and MP consumption but no differences were detected in the intergroup comparison. Omalizumab offered the same clinical benefits in the two cohorts regardless of whether the asthma was caused by a seasonal or a perennial allergen. These results strongly suggest that allergens are the trigger in chronic asthma but that it is the persistent exposure to IgE that causes the chronicity.

  17. Energy prices, equalization and federalism

    Energy Technology Data Exchange (ETDEWEB)

    Courchene, T.J. [Queen' s Univ., Kingston, ON (Canada). School of Policy Studies

    2005-10-01

    A rise in oil prices over the last 30 years has shaped the debate on the equalization formula as well as the nature of fiscal federalism. The oil shocks of 1973 and 1979 contributed to the creation of the National Energy Program (NEP) in 1980 and the Energy Pricing and Taxation Agreement (EPTA) between Ottawa and Alberta in 1981. The current surge in oil prices, to recent highs of $70 a barrel has resulted in a new debate on energy pricing, equalization and fiscal frameworks. This article presented a review of the history of oil and federalism, and proposed a remedy to the horizontal fiscal imbalance by allocating the fixed equalization pool in accordance with fiscal capacity disparities relating to non-resource revenues. An interprovincial revenue-sharing pool was suggested for resource revenues, agreed to and operated by the provinces. It was suggested that after the price spike in 1973 in which the price of oil tripled, a key part of the rationale for imposing export taxes on oil equal to the difference between domestic and world prices was that the federal government could subsidize oil imports into eastern Canada and maintain a uniform domestic price across the country. By continuing to subsidize imports and maintaining a domestic price below the world price, the government has been diverting potential energy revenues from energy-rich provinces and transferring them directly to Canadians in terms of subsidized energy prices. It was noted that energy price surges cannot send equalization payments soaring as they did before because of the 2004 Framework Agreement, in which the overall equalization will be increased to $10.9 billion. A 2-tier approach to equalization was presented, in which it was suggested that the $10.9 billion pool should be allocated with fiscal capacity disparities relating to non-resource revenues. The creation of a revenue sharing pool for resource revenues was recommended. It was suggested that the 2 approaches will result in a strategic

  18. Energy prices, equalization and federalism

    International Nuclear Information System (INIS)

    Courchene, T.J.

    2005-01-01

    A rise in oil prices over the last 30 years has shaped the debate on the equalization formula as well as the nature of fiscal federalism. The oil shocks of 1973 and 1979 contributed to the creation of the National Energy Program (NEP) in 1980 and the Energy Pricing and Taxation Agreement (EPTA) between Ottawa and Alberta in 1981. The current surge in oil prices, to recent highs of $70 a barrel has resulted in a new debate on energy pricing, equalization and fiscal frameworks. This article presented a review of the history of oil and federalism, and proposed a remedy to the horizontal fiscal imbalance by allocating the fixed equalization pool in accordance with fiscal capacity disparities relating to non-resource revenues. An interprovincial revenue-sharing pool was suggested for resource revenues, agreed to and operated by the provinces. It was suggested that after the price spike in 1973 in which the price of oil tripled, a key part of the rationale for imposing export taxes on oil equal to the difference between domestic and world prices was that the federal government could subsidize oil imports into eastern Canada and maintain a uniform domestic price across the country. By continuing to subsidize imports and maintaining a domestic price below the world price, the government has been diverting potential energy revenues from energy-rich provinces and transferring them directly to Canadians in terms of subsidized energy prices. It was noted that energy price surges cannot send equalization payments soaring as they did before because of the 2004 Framework Agreement, in which the overall equalization will be increased to $10.9 billion. A 2-tier approach to equalization was presented, in which it was suggested that the $10.9 billion pool should be allocated with fiscal capacity disparities relating to non-resource revenues. The creation of a revenue sharing pool for resource revenues was recommended. It was suggested that the 2 approaches will result in a strategic

  19. Effects of heat treatment temperature on morphology and properties of opal crystal

    International Nuclear Information System (INIS)

    Duan Tao; China Academy of Engineering Physics, Mianyang; Peng Tongjiang; Chen Jiming; Tang Yongjian

    2008-01-01

    The monodispersed SiO 2 microspheres were synthesized by reactant mixed equally. The colloid crystal templates were assemblied by vertical sedimentation method in ethanol at certain temperatures, and the effects of the heat treatment temperature on the morphology and the properties of opal colloid crystals were investigated. SEM, TCr-DSC results indicate SiO 2 colloid templates should be heat treated at 700-800 degree C, enhancing the conglutination and mechanistic intensity of opal templates. UV-Vis analysis result indicates that the heat treatment process can remove the photonic band gap location of the opal colloid crystals, and with the heat treatment temperature increasing gradually, blue shift occurs and the gap narrows. (authors)

  20. Effects of radiation treatment on foodstuffs

    International Nuclear Information System (INIS)

    Dehne, L.; Boegl, W.

    1980-01-01

    The purpose of this study is to discuss and compile methods and results of irradiation experiments carried out on 54 plant and animal foodstuffs in order to obtain a survey on chemical changes, in particular as regards the reduction of nutritional value and savoriness of irradiated foodstuffs. According to this task, microbiological aspects as well as an interpretation of the experimental results as to the physiology of nutrition and toxicology were not included. The results published by the authors of the original papers were compiled in a kind of dictionary which contains all relevant information such as radiation sources, irradiation conditions, investigation methods, results of chemical or organoleptical changes etc. The most important results were summarized in tables and can be found at the end of this study. Because of the abundance of existing literature the series 'Effects of radiation treatment on foodstuffs' will be continued in Part IV, and the final discussion of the results will be published separately after further data have been included. (orig.) [de

  1. Internationalisation and Equality and Diversity in Higher Education: Merging Identities

    OpenAIRE

    Caruana, V; Ploner, J

    2010-01-01

    Summary This project arises out of Eade and Peacock’s (2009) scoping report, commissioned by Equality Challenge Unit (ECU) entitled Internationalising equality and equalising internationalisation: The intersection between internationalisation and Equality and Diversity in higher education. The principal aim of the current study is to identify the advantages of building on the intersection of Internationalisation and E and D agendas, through an exploration of the effective mechanisms for linki...

  2. Enhancement effect of inter-pass annealing during equal channel angular pressing on grain refinement and ductility of 9Cr1Mo steel

    Energy Technology Data Exchange (ETDEWEB)

    Hao, Ting, E-mail: hao.ting@issp.ac.cn [Key Laboratory of Materials Physics, Institute of Solid State Physics, Chinese Academy of Sciences, P. O. Box 1129, Hefei 230031 (China); Tangi, Haiyin [Key Laboratory of Materials Physics, Institute of Solid State Physics, Chinese Academy of Sciences, P. O. Box 1129, Hefei 230031 (China); Luo, Guangnan [Institute of Plasma Physics, Chinese Academy of Sciences, P.O. Box 1126, Hefei 230031 (China); Wang, Xianping; Liu, Changsong [Key Laboratory of Materials Physics, Institute of Solid State Physics, Chinese Academy of Sciences, P. O. Box 1129, Hefei 230031 (China); Fang, Qianfeng, E-mail: qffang@issp.ac.cn [Key Laboratory of Materials Physics, Institute of Solid State Physics, Chinese Academy of Sciences, P. O. Box 1129, Hefei 230031 (China)

    2016-06-14

    To obtain enhanced mechanical property in both the strength and the ductility, 9Cr1Mo steel (T91) was severely deformed by equal channel angular pressing (ECAP) combined with an additional inter-pass annealing. Tensile results show that the additional inter-pass annealing can significantly improve the ductility (i.e. 18% of the total elongation after four-pass extrusion with the inter-pass annealing) but slightly decrease the tensile strength comparing with the case without the inter-pass annealing (i.e. 10% of the total elongation after four-pass ECAP processing). The average grain size of the two passes ECAP-processed materials with the inter-pass annealing (~0.8 µm) is smaller than that of the sample without inter-pass annealing (~2 µm), and the fraction of the high angle grain boundaries in the samples with the inter-pass annealing (~40%) is higher than that of ~34% (two-pass ECAP) without the inter-pass annealing based on electron backscattering diffraction analysis. The crystallite size and dislocation density were evaluated by means of the modified Williamson-Hall plot based on X-ray diffraction analysis. The microstructural analysis indicates that the enhanced ductility of the ECAP processed and inter-pass annealed materials can be attributed to the relatively smaller grain sizes, larger crystallite sizes and lower dislocation densities.

  3. Enhancement effect of inter-pass annealing during equal channel angular pressing on grain refinement and ductility of 9Cr1Mo steel

    International Nuclear Information System (INIS)

    Hao, Ting; Tangi, Haiyin; Luo, Guangnan; Wang, Xianping; Liu, Changsong; Fang, Qianfeng

    2016-01-01

    To obtain enhanced mechanical property in both the strength and the ductility, 9Cr1Mo steel (T91) was severely deformed by equal channel angular pressing (ECAP) combined with an additional inter-pass annealing. Tensile results show that the additional inter-pass annealing can significantly improve the ductility (i.e. 18% of the total elongation after four-pass extrusion with the inter-pass annealing) but slightly decrease the tensile strength comparing with the case without the inter-pass annealing (i.e. 10% of the total elongation after four-pass ECAP processing). The average grain size of the two passes ECAP-processed materials with the inter-pass annealing (~0.8 µm) is smaller than that of the sample without inter-pass annealing (~2 µm), and the fraction of the high angle grain boundaries in the samples with the inter-pass annealing (~40%) is higher than that of ~34% (two-pass ECAP) without the inter-pass annealing based on electron backscattering diffraction analysis. The crystallite size and dislocation density were evaluated by means of the modified Williamson-Hall plot based on X-ray diffraction analysis. The microstructural analysis indicates that the enhanced ductility of the ECAP processed and inter-pass annealed materials can be attributed to the relatively smaller grain sizes, larger crystallite sizes and lower dislocation densities.

  4. Residual stress and its effect on the mechanical properties of Y-doped Mg alloy fabricated via back-pressure assisted equal channel angular pressing (ECAP-BP)

    Energy Technology Data Exchange (ETDEWEB)

    Shen, Jianghua, E-mail: j_shen@live.cn [Department of Mechanical Engineering, University of North Carolina at Charlotte, Charlotte, NC 28223-0001 (United States); School of Aeronautics, Northwestern Polytechnical University, Xi’an 710072 (China); Gärtnerová, Viera [Laboratory of Nanostructures and Nanomaterials, Institute of Physics of the ASCR, Na Slovance 2, CZ – 182 21, Prague 8 (Czech Republic); Kecskes, Laszlo J. [US Army Research Laboratory, Aberdeen Proving Ground, MD 21005-5069 (United States); Kondoh, Katsuyoshi [Joining and Welding Research Institute, Osaka University, 11-1 Mihogaoka, Ibaragi, Osaka 567-0047 (Japan); Jäger, Aleš, E-mail: jager@fzu.cz [Laboratory of Nanostructures and Nanomaterials, Institute of Physics of the ASCR, Na Slovance 2, CZ – 182 21, Prague 8 (Czech Republic); Wei, Qiuming [Department of Mechanical Engineering, University of North Carolina at Charlotte, Charlotte, NC 28223-0001 (United States)

    2016-07-04

    In this study, pure magnesium (Mg) and Mg-0.6 wt% yttrium (Y) binary alloy were fabricated via casting followed by room temperature equal channel angular pressing (ECAP) using an applied back pressure (BP). Microstructural examination after ECAP-BP revealed a fine-grained Mg-Y alloy with a high residual stress level, whereas, the pure Mg exhibited a well-recrystallized microstructure with uniform and equiaxed grains, but retaining very little residual stress. The Y atoms were present in the Mg matrix as solid solutes and acted as dislocation and grain boundary blockers, thus suppressing dynamic recovery and/or recrystallization during the ECAP process. The Mg-Y alloy had an average grain size of ~400 nm, approximately one order smaller than that of pure Mg. The combination of high residual stress and ultrafine grains of the Mg-Y alloy gave rise to a significant difference in its mechanical behavior from that of the pure Mg, under both quasi-static and dynamic compressive loading.

  5. Equal opportunities in the public and private sector

    Directory of Open Access Journals (Sweden)

    Anca Monica Ardeleanu

    2011-12-01

    Full Text Available Equal opportunities are a goal to achieve in Romania at the legislative and institutional/ organizational level.In terms of legislation Romania has made progress, but the institutional mechanisms of the government dealing with gender equality issues are not functioning properly, are not generating a concreate impact on the equal opportunities for women and men.For this reason there is no specific and significant political commitmentto these issue of gender equality in Romania. Gender discrimination is addressed both by anti-discrimination and equal opportunities laws.Equality,fairness and non-discrimination in the workplace environment are present as objective requirements of economic, social and ethical behavior that goes beyond the labor market. Theoretically, on the labor market , both public and private sectors do not accept direct or indirect discrimination at the workplace, espeially during the process of recruitment , training , development, promotion, establishment, payment of the salary and benefits. In practice , the legislation regarding the equal opportunities and equal treatment it is not respected by the employers all the time.Promotion of the policies at the national and organizational level, focused on ensuring equal opportunities , will enhance the social cohesion of the population that will generate economic growrh overall.

  6. Gender Equality and Economic Growth in Brazil

    OpenAIRE

    Pierre-Richard Agénor; Otaviano Canuto

    2013-01-01

    This note studies the long-run impacts of policies aimed at fostering gender equality on economic growth in Brazil. After a brief review of gender issues in Brazil, this note describes a framework for quantifying the growth effects of gender-based policies in developing economies. The analysis is based on a computable overlapping generations (OLG) model that accounts for the impact of acce...

  7. Instrumental variable estimation of treatment effects for duration outcomes

    NARCIS (Netherlands)

    G.E. Bijwaard (Govert)

    2007-01-01

    textabstractIn this article we propose and implement an instrumental variable estimation procedure to obtain treatment effects on duration outcomes. The method can handle the typical complications that arise with duration data of time-varying treatment and censoring. The treatment effect we

  8. COLOUR IMAGE ENHANCEMENT BASED ON HISTOGRAM EQUALIZATION

    OpenAIRE

    Kanika Kapoor and Shaveta Arora

    2015-01-01

    Histogram equalization is a nonlinear technique for adjusting the contrast of an image using its histogram. It increases the brightness of a gray scale image which is different from the mean brightness of the original image. There are various types of Histogram equalization techniques like Histogram Equalization, Contrast Limited Adaptive Histogram Equalization, Brightness Preserving Bi Histogram Equalization, Dualistic Sub Image Histogram Equalization, Minimum Mean Brightness Error Bi Histog...

  9. Treatment with clozapine and its effect on plasma homovanillic acid and norepinephrine concentrations in schizophrenia.

    Science.gov (United States)

    Davidson, M; Kahn, R S; Stern, R G; Hirschowitz, J; Apter, S; Knott, P; Davis, K L

    1993-02-01

    Measurement of plasma concentrations of the dopamine metabolite, homovanillic acid (pHVA), is an indirect tool to assess changes in dopamine turnover. Levels of pHVA have been reported to decrease during treatment with conventional antidopaminergic, neuroleptics, with the decrement correlating with symptomatic improvement in schizophrenic symptoms. Clozapine, an atypical neuroleptic, is the only drug proved to be effective in treatment-refractory patients. However, the mechanism mediating this unique efficacy has not been fully elucidated. This study examined the effect of clozapine on pHVA concentrations in schizophrenic patients. Since clozapine potently binds to alpha 2-adrenergic receptors, plasma norepinephrine (pNE) concentrations were also measured. Twenty-eight treatment-refractory schizophrenic patients (24 men, 4 women) were treated with clozapine (up to 600 mg/day) for 5 weeks, after a minimum 1-week drug-free period. Symptomatology and pHVA and pNE concentrations were measured at the last drug-free day and weekly for 5 weeks. Fourteen patients responded to clozapine treatment, while an equal number did not. Mean pHVA concentrations did not significantly change during treatment with clozapine. Although clozapine tended to lower pHVA concentrations in treatment responders, the effect was small and not significant. Clozapine treatment significantly raised pNE concentrations, but this did not differentiate responders from nonresponders to clozapine. These findings suggest that clozapine's effect on DA turnover is small and that clozapine may be effective in treatment-refractory schizophrenia by mechanisms other than, or in addition to, dopamine receptor blockade. However, since about one-third of NE is metabolized into HVA, the clozapine-induced increase in pNE may have overshadowed a possible lowering effect of clozapine on pHVA.

  10. Nonparametric tests for equality of psychometric functions.

    Science.gov (United States)

    García-Pérez, Miguel A; Núñez-Antón, Vicente

    2017-12-07

    Many empirical studies measure psychometric functions (curves describing how observers' performance varies with stimulus magnitude) because these functions capture the effects of experimental conditions. To assess these effects, parametric curves are often fitted to the data and comparisons are carried out by testing for equality of mean parameter estimates across conditions. This approach is parametric and, thus, vulnerable to violations of the implied assumptions. Furthermore, testing for equality of means of parameters may be misleading: Psychometric functions may vary meaningfully across conditions on an observer-by-observer basis with no effect on the mean values of the estimated parameters. Alternative approaches to assess equality of psychometric functions per se are thus needed. This paper compares three nonparametric tests that are applicable in all situations of interest: The existing generalized Mantel-Haenszel test, a generalization of the Berry-Mielke test that was developed here, and a split variant of the generalized Mantel-Haenszel test also developed here. Their statistical properties (accuracy and power) are studied via simulation and the results show that all tests are indistinguishable as to accuracy but they differ non-uniformly as to power. Empirical use of the tests is illustrated via analyses of published data sets and practical recommendations are given. The computer code in MATLAB and R to conduct these tests is available as Electronic Supplemental Material.

  11. Discrimination and Equality of Opportunity

    OpenAIRE

    J. Ignacio García-Pérez; Antonio Villar

    2009-01-01

    This paper presents a measure of social discrimination based on the principle of equality of opportunity. According to this principle we only have to care about the inequality derived from people’s differential circumstances (and not about outcome differences due to people’s diverse degree of effort). We propose approaching the measurement of group discrimination as the “welfare loss” attributed to the inequality between social groups of similar characteristics. We also provide an empirical a...

  12. Office of Equal Opportunity Programs

    Science.gov (United States)

    Chin, Jennifer L.

    2004-01-01

    The NASA Glenn Office of Equal Opportunity Programs works to provide quality service for all programs and/or to assist the Center in becoming a model workplace. During the summer of 2004, I worked with Deborah Cotleur along with other staff members to create and modify customer satisfaction surveys. This office aims to assist in developing a model workplace by providing functions as a change agent to the center by serving as an advisor to management to ensure equity throughout the Center. In addition, the office serves as a mediator for the Center in addressing issues and concerns. Lastly, the office provides assistance to employees to enable attainment of personal and organizational goals. The Office of Equal Opportunities is a staff office which reports and provides advice to the Center Director and Executive Leadership, implements laws, regulations, and presidential executive orders, and provides center wide leadership and assistance to NASA GRC employees. Some of the major responsibilities of the office include working with the discrimination complaints program, special emphasis programs (advisory groups), management support, monitoring and evaluation, contract compliance, and community outreach. During my internship in this office, my main objective was to create four customer satisfaction surveys based on EO retreats, EO observances, EO advisory boards, and EO mediation/counseling. I created these surveys after conducting research on past events and surveys as well as similar survey research created and conducted by other NASA centers, program for EO Advisory group members, leadership training sessions for supervisors, preventing sexual harassment training sessions, and observance events. I also conducted research on the style and format from feedback surveys from the Marshall Equal Opportunity website, the Goddard website, and the main NASA website. Using the material from the Office of Equal Opportunity Programs at Glenn Research Center along with my

  13. Equal is as equal does: challenging Vatican views on women.

    Science.gov (United States)

    1995-01-01

    The authors of this piece are women from the Roman Catholic tradition who are critical of the Vatican position on women's rights. The Report of the Holy See in Preparation for the Fourth World Conference on Women reveals a religious fundamentalism that misuses tradition and anthropology to limit women's roles and rights. The Vatican is itself a self-proclaimed state that offers women neither opportunities nor protections within its own organization, and there is no evidence of women's participation in the preparation of its report. The Vatican document constructs a vision of women and men in which men are normative persons, whose dignity is conferred by their humanity, and women are the variant other, defined by and granted dignity by their reproductive and mothering functions. The Vatican document is anti-feminist. It criticizes the "radical feminists" of the 1960s for trying to deny sexual differences, and accuses today's Western feminists of ignoring the needs of women in developing countries while pursuing selfish and hedonistic goals. It makes no recognition of the work of feminists to improve the lives of women worldwide. The Vatican document claims to support women's equality, but it qualifies each statement of equality with a presumption of difference. The document defines women as vulnerable without naming men as responsible for the oppression and violence to which women are vulnerable. It ridicules as feminist cant the well-documented fact that the home is the setting of most violence against women. The Vatican decries the suffering families undergo as a result of cumpulsory birth control and abortion policies, while it would deny families sex education, contraceptives, and safe abortion, thereby making pregnancy cumpulsory. A new vision of social justice is needed, one that: 1) rests on a radical equality, in which both women and men are expected to contribute to work, education, culture, morality, and reproduction; 2) accepts a "discipleship of equals

  14. Cancer treatment: fertility and sexual side effects in women

    Science.gov (United States)

    ... Cancer treatment: fertility and sexual side effects in women To use the sharing features on this page, ... Bladder cancer Types of Sexual Side Effects For women, the most common sexual side effects include: Loss ...

  15. Therapeutic effect of beta radiation on onychomycosis: An innovative treatment

    International Nuclear Information System (INIS)

    Afroz, S.; Islam, N.; Rashid, H.; Shahidullah, M.; Ali, S.; Islam, S.K.M.; Hossain, S.; Ali, N.

    2005-01-01

    griseofulvin (500 mg daily for 6 weeks). Patients were followed up for 24 weeks. Efficacy of the treatment was evaluated in all 287 patients while 43 (13.03%) cases were dropped out from the initial allocation. At the end of the follow up period (6 months after discontinuation of treatment) mycological cure rate was achieved 41 (42.70%), 36 (38.70%) and 65 (66.33%) in Group-A, Group-B and Group-C respectively. The mycological cure rate was highly significant (P=0.000) and considered to be the acceptable outcome of treatment. Clinical cure rate was considered as another way of assessment. Percentage of clinical cure rate was similar as mycological cure rate and equally significant (P=0.000). Recurrence rate of the disease was highest in griseofulvin-induced patients 21 (21.88%) and in beta radiation exposed patients was 14 (15.06%). This rate was least in combination therapy group of griseofulvin and beta radiation 4 (4.08%). Cure rate in Group C is significantly higher than Group A and B as well (P=0.000). Several known side effects causing systemic involvement of oral drugs are already being experienced, side effects like blackening of surrounding soft tissue of nail were observed which were transient and self-limiting. Further to this, all sample population underwent for biochemical and haematological tests pre and post radiation application. No significant change of tests results were observed excluding any observable radiation side affects to this particular type of radiation application. It can be concluded that the proposed new beta radiation treatment modality for onychomycosis exhibited a low risk- benefit ratio. It is well-tolerated and efficacious method to treat onychomycosis. From the observations of the present study it may be considered worthy to comment that in Group C as the cure rate is highest, recurrent rate is the lowest, duration and cost of treatment are significantly less, this modality of treatment can be considered as the more acceptable procedure for

  16. Herbal Treatment for Anxiety: Is It Effective?

    Science.gov (United States)

    ... anxiety generally need medical treatment or psychological counseling (psychotherapy) for symptoms to improve. With Brent A. Bauer, ... dietary supplements wisely. National Center for Complementary and Integrative Health. https://nccih.nih.gov/health/supplements/wiseuse. ...

  17. Treatment compliance and effectiveness in complex PTSD patients with co-morbid personality disorder undergoing stabilizing cognitive behavioral group treatment: a preliminary study

    Directory of Open Access Journals (Sweden)

    Ethy Dorrepaal

    2013-11-01

    Full Text Available Background: In the empirical and clinical literature, complex posttraumatic stress disorder (PTSD and personality disorders (PDs are suggested to be predictive of drop-out or reduced treatment effectiveness in trauma-focused PTSD treatment. Objective: In this study, we aimed to investigate if personality characteristics would predict treatment compliance and effectiveness in stabilizing complex PTSD treatment. Method: In a randomized controlled trial on a 20-week stabilizing group cognitive behavioral treatment (CBT for child-abuse-related complex PTSD, we included 71 patients of whom 38 were randomized to a psycho-educational and cognitive behavioral stabilizing group treatment. We compared the patients with few PD symptoms (adaptive (N=14 with the non-adaptive patients (N=24 as revealed by a cluster analysis. Results: We found that non-adaptive patients compared to the adaptive patients showed very low drop-out rates. Both non-adaptive patients, classified with highly different personality profiles “withdrawn” and “aggressive,” were equally compliant. With regard to symptom reduction, we found no significant differences between subtypes. Post-hoc, patients with a PD showed lower drop-out rates and higher effect sizes in terms of complex PTSD severity, especially on domains that affect regulation and interpersonal problems. Conclusion: Contrary to our expectations, these preliminary findings indicate that this treatment is well tolerated by patients with a variety of personality pathology. Larger sample sizes are needed to study effectiveness for subgroups of complex PTSD patients.

  18. Fixed Points on the Real numbers without the Equality Test

    DEFF Research Database (Denmark)

    Korovina, Margarita

    2002-01-01

    In this paper we present a study of definability properties of fixed points of effective operators on the real numbers without the equality test. In particular we prove that Gandy theorem holds for the reals without the equality test. This provides a useful tool for dealing with recursive...

  19. Fixed Points on Abstract Structures without the Equality Test

    DEFF Research Database (Denmark)

    Korovina, Margarita

    2002-01-01

    The aim of this talk is to present a study of definability properties of fixed points of effective operators on abstract structures without the equality test. The question of definability of fixed points of -operators on abstract structures with equality was first studied by Gandy, Barwise, Mosch...

  20. Fair Equality of Opportunity in Our Actual World

    Science.gov (United States)

    Sachs, Benjamin

    2016-01-01

    Fair equality of opportunity, a principle that governs the competition for desirable jobs, can seem irrelevant in our actual world, for two reasons. First, parents have broad liberty to raise their children as they see fit, which seems to undermine the fair equality of opportunity-based commitment to eliminating the effects of social circumstances…

  1. Some consequences of assuming simple patterns for the treatment effect over time in a linear mixed model.

    Science.gov (United States)

    Bamia, Christina; White, Ian R; Kenward, Michael G

    2013-07-10

    Linear mixed models are often used for the analysis of data from clinical trials with repeated quantitative outcomes. This paper considers linear mixed models where a particular form is assumed for the treatment effect, in particular constant over time or proportional to time. For simplicity, we assume no baseline covariates and complete post-baseline measures, and we model arbitrary mean responses for the control group at each time. For the variance-covariance matrix, we consider an unstructured model, a random intercepts model and a random intercepts and slopes model. We show that the treatment effect estimator can be expressed as a weighted average of the observed time-specific treatment effects, with weights depending on the covariance structure and the magnitude of the estimated variance components. For an assumed constant treatment effect, under the random intercepts model, all weights are equal, but in the random intercepts and slopes and the unstructured models, we show that some weights can be negative: thus, the estimated treatment effect can be negative, even if all time-specific treatment effects are positive. Our results suggest that particular models for the treatment effect combined with particular covariance structures may result in estimated treatment effects of unexpected magnitude and/or direction. Methods are illustrated using a Parkinson's disease trial. Copyright © 2012 John Wiley & Sons, Ltd.

  2. Ultrafine grained steels processed by equal channel angular pressing

    International Nuclear Information System (INIS)

    Shin, Dong Hyuk; Park, Kyung-Tae

    2005-01-01

    Recent development of ultrafine grained (UFG) low carbon steels by using equal channel angular pressing (ECAP) and their room temperature tensile properties are reviewed, focusing on the strategies overcoming their inherent mechanical drawbacks. In addition to ferrite grain refinement, when proper post heat treatments are imposed, carbon atom dissolution from pearlitic cementite during ECAP can be utilized for microstructural modification such as uniform distribution of nano-sized cementite particles or microalloying element carbides inside UFG ferrite grains and fabrication of UFG ferrite/martensite dual phase steel. The utilization of nano-sized particles is effective on improving thermal stability of UFG low carbon ferrite/pearlite steel but less effective on improving its tensile properties. By contrast, UFG ferrite/martensite dual phase steel exhibits an excellent combination of ultrahigh strength, large uniform elongation and extensive strain hardenability

  3. Equal pay for work of equal value in terms of the Employment Equity ...

    African Journals Online (AJOL)

    Lastly, this article seeks to ascertain whether the EEA (including the Employment Equity Regulations) provides an adequate legal framework for determining an equal pay for work of equal value claim. Keywords: Equal pay; Employment Equity Act; Equality Act; International Labour Organisation; Equal Pay Guide; Equal ...

  4. Educational Equality: Luck Egalitarian, Pluralist and Complex

    Science.gov (United States)

    Calvert, John

    2014-01-01

    The basic principle of educational equality is that each child should receive an equally good education. This sounds appealing, but is rather vague and needs substantial working out. Also, educational equality faces all the objections to equality per se, plus others specific to its subject matter. Together these have eroded confidence in the…

  5. The restructuring of the fiscal equalization system in Croatia

    Directory of Open Access Journals (Sweden)

    Marko Primorac

    2014-12-01

    Full Text Available The aim of this paper is to propose a model of fiscal equalization in Croatia. This paper tests the hypothesis of a lack of effectiveness of the existing fiscal equalization model compared to a model that would be based on alleviating the difference in the potential to collect revenue from the personal income tax and surtax. Fiscal inequalities of local government units are determined first under the current equalization system by calculating the Gini coefficients and graphically presented with Lorenz curves. Thereafter, a distribution of equalization grants is simulated based on the new (proposed model. The effectiveness of the proposed model in alleviating the fiscal inequalities is determined in relation to the effectiveness of the current equalization system. It was found that the model based on equalizing the difference in the capacity to collect revenue from the personal income tax and surtax alleviates inequalities in fiscal capacities of local government units much better than the existing system at the same cost. The main conclusion is that the fiscal equalization in Croatia should urgently be redesigned in order to improve efficiency and fairness, but also the transparency and credibility of the equalization system.

  6. Is all support equal? The moderating effects of supervisor, coworker, and organizational support on the link between emotional labor and job performance

    Directory of Open Access Journals (Sweden)

    Hyun Jeong Kim

    2017-04-01

    Full Text Available This study was designed to examine the moderating roles of perceived supervisor, coworker, and organizational support in the relationship between emotional labor and job performance in the airline service context. A sample of flight attendants working for one major airline company in South Korea participated in this study. The flight attendants’ official job performance data were provided by the airline company. For data analyses, a series of hierarchical moderated regression analyses were employed. The results showed differential moderation effects of the three sources of support at work. Specifically, the positive relationship between deep acting and job performance was strengthened by perceived supervisor and coworker support. The negative relationship between surface acting and job performance was exacerbated by perceived supervisor support, indicating the reverse buffering effect. Perceived organizational support showed only main effects on employee performance with no moderation effects.

  7. Effectiveness of propanolol for treatment of infantile haemangioma

    DEFF Research Database (Denmark)

    Andersen, Ida Gillberg; Rechnitzer, Catherine; Charabi, Birgitte

    2014-01-01

    : This study was retrospective and based on a review of children treated for IH with propranolol from the 2010-2012 period at Rigshospitalet. RESULTS: Overall, propranolol was effective in all but one child (97%). The majority of the children (84%) were treated with an initial dose of 1 mg/kg/day, which...... was considered sufficient in most cases (71%). Children who started treatment before five months of age had a significantly better response than children who started treatment at a later age. No relation was found between location of IH and the effect of treatment. There were only few and mild side effects....... CONCLUSION: Propranolol is effective in the treatment of IH and it has only few and mild side effects. In most cases, a low dose of 1 mg/kg/day was sufficient. Early initiation of treatment is recommended as the response to treatment was better in younger children and because early initiation helps prevent...

  8. Gender Equality in Agricultural Education

    Directory of Open Access Journals (Sweden)

    N. Jayakumar

    2016-05-01

    “Increased women’s enrollment in agricultural courses” as one among the strategies when addressing gender issues in the education and training components of agricultural development projects. In this context the study was carried out to ascertain the representation of women and their academic achievement in agricultural education. The study revealed that almost equal representation was found for women in agricultural course and they were also provided better quality education in their schooling, in the form of English medium education and education in private schools. Recent trends for the past four years showed a higher percentage of enrollments of women in agricultural course than men. The growth rate was also higher for the female students. Women also showed a significantly higher percentage of academic achievement than men. These positive indicators provide sufficient signals for equality of women in agricultural course and have positive implications for development of the agricultural sector in future.

  9. Effect of aspirin treatment on chondromalacia patellae.

    OpenAIRE

    Bentley, G; Leslie, I J; Fischer, D

    1981-01-01

    Twenty-nine patients (21 females and 8 males) with chondromalacia patellae diagnosed by arthroscopy were randomly allocated to receive aspirin or placebo for 3 months. Clinical and arthroscopic examination after 3 months showed no significant change in symptoms, signs, or macroscopic appearances in either group. Surgical treatment was performed in 14 patients for deteriorating symptoms.

  10. Effect of aspirin treatment on chondromalacia patellae.

    Science.gov (United States)

    Bentley, G; Leslie, I J; Fischer, D

    1981-01-01

    Twenty-nine patients (21 females and 8 males) with chondromalacia patellae diagnosed by arthroscopy were randomly allocated to receive aspirin or placebo for 3 months. Clinical and arthroscopic examination after 3 months showed no significant change in symptoms, signs, or macroscopic appearances in either group. Surgical treatment was performed in 14 patients for deteriorating symptoms. Images PMID:7008711

  11. Musical hallucinations : Review of treatment effects

    NARCIS (Netherlands)

    Coebergh, Jan A. F.; Lauw, R. F.; Bots, R.; Sommer, I. E. C.; Blom, J. D.

    2015-01-01

    Background: Despite an increased scientific interest in musical hallucinations over the past 25 years, treatment protocols are still lacking. This may well be due to the fact that musical hallucinations have multiple causes, and that published cases are relatively rare. Objective: To review the

  12. Musical hallucinations : review of treatment effects

    NARCIS (Netherlands)

    Coebergh, Jan A F; Lauw, R F; Bots, R; Sommer, I E C; Blom, J D

    2015-01-01

    BACKGROUND: Despite an increased scientific interest in musical hallucinations over the past 25 years, treatment protocols are still lacking. This may well be due to the fact that musical hallucinations have multiple causes, and that published cases are relatively rare. OBJECTIVE: To review the

  13. Effect of heat treatment temperature on microstructure

    Indian Academy of Sciences (India)

    The results of electrochemical performance measurements for the HCSs as anode material for lithium ion batteries indicate that the discharge capacity of the HCSs is improved after heat treatment at 800°C compared with the as-prepared HCSs and have a maximum value of 357 mAh/g and still retains 303 mAh/g after 40 ...

  14. Effects of plasma treatment on wounds

    NARCIS (Netherlands)

    Tipa, R.S.; Stoffels - Adamowicz, E.; Lim, C.T.; Goh, J.C.H.

    2009-01-01

    Cold plasma treatment of wounds is gaining much interest, because it will offer a non-contact, painless and harmless therapy to manage large-area lesions (burn wounds, chronic ulcerations). One of the important issues in plasma wound healing is the safety of the method. In this work we study in

  15. Effects of ecosystem-based management treatments

    Science.gov (United States)

    Michael G. Harrington; Carl E. Fiedler; Stephen F. Arno; Ward W. McCaughey; Leon J. Theroux; Clinton E. Carlson; Kristin L. Zouhar; Thomas H. DeLuca; Donald J. Bedunah; Dayna M. Ayers; Elizabeth A. Beringer; Sallie J. Hejl; Lynn Bacon; Robert E. Benson; Jane Kapler Smith; Rick Floch

    1999-01-01

    The prescribed burn treatments were applied to reduce pre-existing and new slash fuel loadings, reduce understory tree density to lower crown fire potential, stimulate vigor of decadent understory vegetation, produce mineral seedbeds for seral species establishment, and increase availability of mineral nutrients. To test the feasibility of prescribed burning under a...

  16. Nonparametric Bounds and Sensitivity Analysis of Treatment Effects

    Science.gov (United States)

    Richardson, Amy; Hudgens, Michael G.; Gilbert, Peter B.; Fine, Jason P.

    2015-01-01

    This paper considers conducting inference about the effect of a treatment (or exposure) on an outcome of interest. In the ideal setting where treatment is assigned randomly, under certain assumptions the treatment effect is identifiable from the observable data and inference is straightforward. However, in other settings such as observational studies or randomized trials with noncompliance, the treatment effect is no longer identifiable without relying on untestable assumptions. Nonetheless, the observable data often do provide some information about the effect of treatment, that is, the parameter of interest is partially identifiable. Two approaches are often employed in this setting: (i) bounds are derived for the treatment effect under minimal assumptions, or (ii) additional untestable assumptions are invoked that render the treatment effect identifiable and then sensitivity analysis is conducted to assess how inference about the treatment effect changes as the untestable assumptions are varied. Approaches (i) and (ii) are considered in various settings, including assessing principal strata effects, direct and indirect effects and effects of time-varying exposures. Methods for drawing formal inference about partially identified parameters are also discussed. PMID:25663743

  17. Cost-effectiveness analysis of treatment alternatives for beef bulls with preputial prolapse.

    Science.gov (United States)

    Kasari, T R; McGrann, J M; Hooper, R N

    1997-10-01

    To develop an economic model for comparing cost-effectiveness of medical and surgical treatment versus replacement of beef bulls with preputial prolapse. Economic analysis. Estimates determined from medical records of bulls treated for preputial prolapse at our hospital and from information about treatment of bulls published elsewhere. Annual depreciation cost for treatment (ADC(T)) and replacement (ADC(R)) were calculated. Total investment for an injured bull equaled the sum of salvage value, maintenance cost, and expected cost of the treatment option under consideration. Total investment for a replacement bull was purchase price. Net present value of cost was calculated for each year of bull use. Sensitivity analyses were constructed to determine the value that would warrant treatment of an injured bull. The decision to treat was indicated when ADC(T) was less than ADC(R). In our example, it was more cost-effective for owners to cull an injured bull. The ADC(R) was $97 less than ADC(T) for medical treatment ($365 vs $462) and $280 less than ADC(T) for surgical treatment ($365 vs $645). Likewise, net present value of cost values indicated that it was more cost-effective for owners to cull an injured bull. Sensitivity analysis indicated treatment decisions were justified on the basis of replacement value or planned number of breeding seasons remaining for the bull. The model described here can be used by practitioners to provide an objective basis to guide decision making of owners who seek advice on whether to treat or replace bulls with preputial prolapse.

  18. Estimating the effect of treatment rate changes when treatment benefits are heterogeneous: antibiotics and otitis media.

    Science.gov (United States)

    Park, Tae-Ryong; Brooks, John M; Chrischilles, Elizabeth A; Bergus, George

    2008-01-01

    Contrast methods to assess the health effects of a treatment rate change when treatment benefits are heterogeneous across patients. Antibiotic prescribing for children with otitis media (OM) in Iowa Medicaid is the empirical example. Instrumental variable (IV) and linear probability model (LPM) are used to estimate the effect of antibiotic treatments on cure probabilities for children with OM in Iowa Medicaid. Local area physician supply per capita is the instrument in the IV models. Estimates are contrasted in terms of their ability to make inferences for patients whose treatment choices may be affected by a change in population treatment rates. The instrument was positively related to the probability of being prescribed an antibiotic. LPM estimates showed a positive effect of antibiotics on OM patient cure probability while IV estimates showed no relationship between antibiotics and patient cure probability. Linear probability model estimation yields the average effects of the treatment on patients that were treated. IV estimation yields the average effects for patients whose treatment choices were affected by the instrument. As antibiotic treatment effects are heterogeneous across OM patients, our estimates from these approaches are aligned with clinical evidence and theory. The average estimate for treated patients (higher severity) from the LPM model is greater than estimates for patients whose treatment choices are affected by the instrument (lower severity) from the IV models. Based on our IV estimates it appears that lowering antibiotic use in OM patients in Iowa Medicaid did not result in lost cures.

  19. Side effects as influencers of treatment outcome.

    Science.gov (United States)

    Sharif, Zafar

    2008-01-01

    Research relative to the efficacy of a therapeutic agent commands a clinician's greatest interest, but treatment decisions are made based on optimizing efficacy and tolerability/safety considerations. Second-generation atypical antipsychotic drugs are a study in the importance of taking a careful look at the full benefit-risk profile of each drug. The disorders that atypical antipsychotics are approved to treat--schizophrenia, schizoaffective disorder, and bipolar disorder--are associated with an increased rate of certain medical comorbidities compared to the general population. Between-drug differences in efficacy are relatively modest for the atypicals, or between atypicals and conventionals, while differences in safety and tolerability are larger and more clinically relevant. The current article will provide a brief summary of safety-related issues that influence treatment outcome and choice of drug.

  20. Computational Study of Film Cooling Effectiveness for a Comparison of Cylindrical, Square and Triangular Holes of Equal Cross-Sectional Area

    Directory of Open Access Journals (Sweden)

    Fayyaz Hassan Asghar

    2010-10-01

    Full Text Available Film cooling effectiveness is studied computationally for a comparison of circular, square and two types of equilateral triangular holes with an inclination of 30o with streamwise direction. Reynolds number based on the freestream velocity and hole diameter is 10364. Length to diameter ratio of circular hole is 4, which is representative of gas turbine engines. The coolant to mainstream density ratio is 0.92. Main flow is supplied at the temperature of 293.15K and coolant is supplied at 318.15K. Centerline and laterally averaged effectiveness are presented for film cooling measurements. Current computational results for circular hole are compared with experimental results. Computational results are well in agreement with the experimental results even for high blowing ratios. Blowing ratios ranging from 0.33-2.0 have been investigated. It is observed that triangular hole having lateral straight edge on leeward side shows much higher effectiveness values than circular film cooling hole case in the near hole region and almost similar coolant jet height as that in case of circular film cooling. Also it is observed that triangular hole having lateral straight edge on windward side and converging corner on leeward side shows lesser coolant jet height and higher film cooling effectiveness in the region x/D>10, especially at blowing ratios greater than 1.0.

  1. Clinical effect of platelet rich plasma in the treatment of periodontal intrabony defects.Systematic review and meta-analysis.

    Directory of Open Access Journals (Sweden)

    Heber Arbildo

    2017-04-01

    Full Text Available Introduction: One of the consequences of periodontitis is periodontal intrabony defects (PID. Various biomaterials have been used for its treatment, but there is still no biomaterial considered as the gold standard. Current research is focused on the use of platelet-rich plasma (PRP for the treatment of PID. Objective: To determine the clinical effect of PRP in the treatment of PID through a systematic review with meta-analysis. Materials and Methods: A literature search was conducted until February 2017 in the biomedical databases: Pubmed, Embase, Scielo, Science Direct, SIGLE, LILACS, IBECS, and the Cochrane Central Register of Clinical Trials. The criteria for the selection of the studies, which were randomized clinical trials, were the following: articles or papers published in the last 5 years, reporting clinical effects, with a follow-up time equal to or greater than 6 months, and a sample size equal to or greater than 10 patients reporting the use of PRP as a treatment for PID. The methodological quality of the studies was analyzed using the Cochrane Handbook of Systematic Reviews of Interventions as a reference. Results: The search strategy yielded nine articles reporting a reduction in probing depth and gingival recession, and an increase in clinical insertion level when using PRP alone or in combination with another biomaterial. Conclusion: The reviewed literature suggests that the use of PRP in the treatment of PID has a positive clinical effect.

  2. Clinical effect of platelet rich fibrin in the treatment of periodontal intrabony defects. Systematic review and meta-analysis.

    Directory of Open Access Journals (Sweden)

    Heber Arbildo.

    2017-05-01

    Full Text Available Background: There is currently no gold standard biomaterial for the treatment of periodontal intrabony defects (PIDs. One of the current options is the use of platelet-rich fibrin (PRF. Objective: To determine the clinical effect of PRF in the treatment of PID through a systematic review and meta-analysis. Materials and Methods: A literature search was conducted up to February 2017 in the following biomedical databases: Pubmed, Embase, Scielo, Science Direct, SIGLE, LILACS and in the Cochrane Central Register of Clinical Trials. The selection criteria included: randomized clinical trials published in the last 5 years, reporting clinical effects (probing depth, clinical insertion level or gingival recession, with a follow-up time equal to or greater than 6 months, and sample size larger than or equal to 10 patients reporting the use of PRF as a treatment for PID. The methodological quality of the studies was analyzed using the Cochrane Handbook of Systematic Reviews of Interventions as a reference. Results: The search strategy yielded 20 articles. A reduction in probing depth and an increase in clinical insertion level or a reduction in gingival recession is reported, when using PRF alone or in combination with another biomaterial or substance that stimulates tissue regeneration. Conclusion: The literature suggests that the use of PRF in the treatment of PIDs has a beneficial clinical effect when compared to control treatments.

  3. Job satisfaction in terms of social gender equality in employees and its effect on the corporate reputation: The sample of ERU academicians

    OpenAIRE

    Mazıcı, Emel Tanyeri; Gölgeli, Kürşad

    2017-01-01

    Corporate reputation consists of the totalof emotions, opinions and perceptions of all the shareholders of theinstitution. Company employees, who has an important place within theseshareholders also play an effective role in success and continuity of thecompany by being affected from the activities, directly or indirectly. At thispoint, in the forming of the emotions, opinions and perceptions of employees,job satisfaction that is achieved in time has the key importance. Thus, theemployees who...

  4. Effectiveness of Acupuncture in the Treatment of Gulf War Illness

    Science.gov (United States)

    2013-01-01

    325. 7 Wigers SH, Stiles TC, Vogael PA. Effects of aerobic exercise versus stress management treatment in fibromyalgia : a 4.5 year prospective study... Treatment of Gulf War Illness PRINCIPAL INVESTIGATOR: Lisa Conboy, M.A., M.S., ScD...December 2012 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Effectiveness of Acupuncture in the Treatment of Gulf War Illness 5b. GRANT NUMBER W81XWH

  5. Klystron equalization for RF feedback

    International Nuclear Information System (INIS)

    Corredoura, P.

    1993-01-01

    The next generation of colliding beam storage rings support higher luminosities by significantly increasing the number of bunches and decreasing the spacing between respective bunches. The heavy beam loading requires large RF cavity detuning which drives several lower coupled bunch modes very strongly. One technique which has proven to be very successful in reducing the coupled bunch mode driving impedance is RF feedback around the klystron-cavity combination. The gain and bandwidth of the feedback loop is limited by the group delay around the feedback loop. Existing klystrons on the world market have not been optimized for this application and contribute a large portion of the total loop group delay. This paper describes a technique to reduce klystron group delay by adding an equalizing filter to the klystron RF drive. Such a filter was built and tested on a 500 kill klystron as part of the on going PEP-II R ampersand D effort here at SLAC

  6. The Equity-Equality Conflict

    DEFF Research Database (Denmark)

    Scheuer, Steen

    2013-01-01

    -for-performance systems) perceived as fair and when are they not? When can differences in contribution (equity) overrule the social norm of equality? Which contingent reward structure should be applied for teamwork members, if any? Which structure to motivate employees to a continuous search for smarter working......This article investigatesthe factors that determine workplace actors’ appeal to social norms of fairness in some situations and what ‘fairness’ is perceived as consisting of. When is a pay level considered as relativity fair, and when is it not? When are contingent pay systems (i.e. pay...... procedures and solutions? These are central concerns of motivation theory, where rational choice decisions are counterbalanced by endowment effectsor other fairness concerns. Management is placed in a dilemma between what is, e.g., an economically rational structure of incentives, on the one hand, and what...

  7. Treatment selection in a randomized clinical trial via covariate-specific treatment effect curves.

    Science.gov (United States)

    Ma, Yunbei; Zhou, Xiao-Hua

    2017-02-01

    For time-to-event data in a randomized clinical trial, we proposed two new methods for selecting an optimal treatment for a patient based on the covariate-specific treatment effect curve, which is used to represent the clinical utility of a predictive biomarker. To select an optimal treatment for a patient with a specific biomarker value, we proposed pointwise confidence intervals for each covariate-specific treatment effect curve and the difference between covariate-specific treatment effect curves of two treatments. Furthermore, to select an optimal treatment for a future biomarker-defined subpopulation of patients, we proposed confidence bands for each covariate-specific treatment effect curve and the difference between each pair of covariate-specific treatment effect curve over a fixed interval of biomarker values. We constructed the confidence bands based on a resampling technique. We also conducted simulation studies to evaluate finite-sample properties of the proposed estimation methods. Finally, we illustrated the application of the proposed method in a real-world data set.

  8. Cost effectiveness of Tuberculosis Treatment from the Patients ...

    African Journals Online (AJOL)

    ... Directly Observed Treatment Short course is more cost effective from the patients' point of view. DOTS needs to be re-focused out of the hospitals and clinics and made community based in view of the increasing TB caseload occasioned by HI V/AIDS. Key Words: Cost effectiveness, Tuberculosis treatment, personal cost, ...

  9. Frequency of streamflow measurements required to determine forest treatment effects

    Science.gov (United States)

    Kenneth G. Reinhart

    1964-01-01

    Most of the stream-discharge records for our experimental watersheds are taken by continuous measurements. But the question arises: are continuous measurements necessary to determine effects of forest treatments? Or could treatment effects be determined by measurement of discharge at intervals, say, once a day or once a week?

  10. Effects of Cancer Treatment on Fertility (For Parents)

    Science.gov (United States)

    ... Mind Sexual Health Food & Fitness Diseases & Conditions Infections Drugs & Alcohol School & Jobs Sports Expert Answers (Q&A) Staying Safe Videos for Educators Search English Español Effects of Cancer Treatment on Fertility KidsHealth / For Parents / Effects of Cancer Treatment on ...

  11. Adverse effects of orthodontic treatment: A clinical perspective

    Science.gov (United States)

    Talic, Nabeel F.

    2011-01-01

    Orthodontic treatment is associated with a number of adverse effects, such as root resorption, pain, pulpal changes, periodontal disease, and temporomandibular dysfunction (TMD). Orthodontists should be aware of these effects and associated risk factors. Risk factors linked to root resorption include the duration of treatment, length, and shape of the root, trauma history, habits, and genetic predisposition. PMID:24151415

  12. Equal Pay for Work of Equal Value in Terms of the Employment Equity Act 55 of 1998: Lessons from the International Labour Organisation and the United Kingdom

    Directory of Open Access Journals (Sweden)

    Shamier Ebrahim

    2016-07-01

    Full Text Available Equal pay is an area of employment law that is complex and not easily understood. This complexity is recognised by the International Labour Organisation (ILO, which notes that equal pay for work of equal value has proved to be difficult to understand, both with regard to what it entails and in its application. Amendments have been made to the Employment Equity Act 55 of 1998 (EEA to include a specific provision to regulate equal pay claims in the form of section 6(4-(5 of the EEA. The amendments were made in terms of the Employment Equity Amendment Act 47 of 2013, which came into effect on 1 August 2014 by presidential proclamation. Prior to section 6(4, the EEA did not contain a specific provision regulating equal pay claims. Claims could be brought in terms of section 6(1 of the EEA, which prohibits unfair discrimination on a number of grounds. The recent amendments to the EEA in the form of section 6(4-(5 (including the Employment Equity Regulations and the Code of Good Practice on Equal Pay for Work of Equal Value in respect of equal pay claims is a response to the ILO's criticism of South Africa's failure to include specific equal pay provisions in the EEA. Section 6(4 of the EEA provides for three causes of action in respect of equal pay. They are as follows: (a equal pay for the same work; (b equal pay for substantially the same work; and (c equal pay for work of equal value. The first two causes of action are not difficult to understand as opposed to the third cause of action, which is complex. The ILO has recognised the complexity of the third cause of action, "equal pay for work of equal value". In Mangena v Fila South Africa 2009 12 BLLR 1224 (LC, the Labour Court remarked in the context of an equal pay for work of equal value claim that it does not have expertise in job grading and in the allocation of value to particular occupations. This article will deal with the third cause of action only, "equal pay for work of equal value". The

  13. Oculomotor and neuropsychological effects of antipsychotic treatment for schizophrenia

    Directory of Open Access Journals (Sweden)

    Kristian S. Hill

    2009-04-01

    Full Text Available Cognitive enhancement has become an important target for drug therapies in schizophrenia. Treatment development in this area requires assessment approaches that are sensitive to procognitive effects of antipsychotic and adjunctive treatments. Ideally, new treatments will have translational characteristics for parallel human and animal research. Previous studies of antipsychotic effects on cognition have relied primarily on paper-and-pencil neuropsychological testing. No study has directly compared neurophysiological biomarkers and neuropsychological testing as strategies for assessing cognitive effects of antipsychotic treatment early in the course of schizophrenia. Anti psychotic-naive patients with schizophrenia were tested before treatment with risperidone and again 6 weeks later. Matched healthy participants were tested over a similar time period. Test-retest reliability, effect sizes of within-subject change, and multivariate/univariate analysis of variance were used to compare 3 neurophysiological tests (visually guided saccade, memory-guided saccade, and antisaccade with neuropsychological tests covering 4 cognitive domains (executive function, attention, memory, and manual motor function. While both measurement approaches showed robust neurocognitive impairments in patients prior to risperidone treatment, oculomotor biomarkers were more sensitive to treatment-related effects on neurocognitive function than traditional neuropsychological measures. Further, unlike the pattern of modest generalized cognitive improvement suggested by neuropsychological measures, the oculomotor findings revealed a mixed pattern of beneficial and adverse treatment related effects. These findings warrant further investigation regarding the utility of neurophysiological biomarkers for assessing cognitive outcomes of antipsychotic treatment in clinical trials and in early-phase drug development.

  14. Asymmetric inhibitory treatment effects in multilingual aphasia.

    Science.gov (United States)

    Goral, Mira; Naghibolhosseini, Maryam; Conner, Peggy S

    2013-01-01

    Findings from recent psycholinguistic studies of bilingual processing support the hypothesis that both languages of a bilingual are always active and that bilinguals continually engage in processes of language selection. This view aligns with the convergence hypothesis of bilingual language representation. Furthermore, it is hypothesized that when bilinguals perform a task in one language they need to inhibit their other, nontarget language(s) and that stronger inhibition is required when the task is performed in the weaker language than in the stronger one. The study of multilingual individuals who acquire aphasia resulting from a focal brain lesion offers a unique opportunity to test the convergence hypothesis and the inhibition asymmetry. We report on a trilingual person with chronic nonfluent aphasia who at the time of testing demonstrated greater impairment in her first acquired language (Persian) than in her third, later learned language (English). She received treatment in English followed by treatment in Persian. An examination of her connected language production revealed improvement in her grammatical skills in each language following intervention in that language, but decreased grammatical accuracy in English following treatment in Persian. The increased error rate was evident in structures that are used differently in the two languages (e.g., auxiliary verbs). The results support the prediction that greater inhibition is applied to the stronger language than to the weaker language, regardless of their age of acquisition. We interpret the findings as consistent with convergence theories that posit overlapping neuronal representation and simultaneous activation of multiple languages and with proficiency-dependent asymmetric inhibition in multilinguals.

  15. Synchronization of conference presentation sequence using delay equalization approach

    Science.gov (United States)

    Godavari, Rakesh K.; Celenk, Mehmet

    2001-11-01

    In this paper, a delay equalization approach is proposed for cohesive conference presentation with minimal screen- freezing effect. The underlying screen-freezing effect is due to varying delays in the communication channels involved in broadcasting. In turn, this poses a threat to the goal of uniform delay distribution among data packets for synchronized presentation broadcast. We wish to achieve uniformity among packet arrival times to the recipients. This objective is achieved by transforming a given input delay distribution (D) to the desired output density through a delay equalization process. Considering a general case of between packet and frame delay distributions for a given input, the desired output is obtained through a delay equalization process. In case of a specific normal delay distribution, a memory-less system g(D) is determined as an approximation to the delay equalizer such that the equalizer output O(t)equalsg[D(t)] is uniformly distributed in the allowable delay limits of (a,b) assuring the specified quality of service (QoS) parameters. The corresponding delay is added at each recipient workstation, which acts as the wait period required before it begins its designated presentation.For a zero mean normal delay density case, the equalizer transfer function can be given in a closed from solution as O(t)equalsg[D(t)[equals(b-a)]0.5+eft(-D/$RO OTR(0)))[+a, where erf(x) is the standard error function. The histogram approximation is adopted as an asymptotically delay equalization means for general cases. This technique provides a means for modifying the dynamic range of data acquired by altering it into a desired distribution. In experimentation, equalizer characteristic functions are derived for a set of selected input delays to obtain the desired output. The delay equalizer system developed here is suited for deployment in a distributed hierarchical conferencing environment. To accommodate a broadcast continuity, the multimedia presentation is

  16. Carbohydrate-restricted diets high in either monounsaturated fat or protein are equally effective at promoting fat loss and improving blood lipids.

    Science.gov (United States)

    Luscombe-Marsh, Natalie D; Noakes, Manny; Wittert, Gary A; Keogh, Jennifer B; Foster, Paul; Clifton, Peter M

    2005-04-01

    When substituted for carbohydrate in an energy-reduced diet, dietary protein enhances fat loss in women. It is unknown whether the effect is due to increased protein or reduced carbohydrate. We compared the effects of 2 isocaloric diets that differed in protein and fat content on weight loss, lipids, appetite regulation, and energy expenditure after test meals. This was a parallel, randomized study in which subjects received either a low-fat, high-protein (LF-HP) diet (29 +/- 1% fat, 34 +/- 0.8% protein) or a high-fat, standard-protein (HF-SP) diet (45 +/- 0.6% fat, 18 +/- 0.3% protein) during 12 wk of energy restriction (6 +/- 0.1 MJ/d) and 4 wk of energy balance (7.4 +/- 0.3 MJ/d). Fifty-seven overweight and obese [mean body mass index (in kg/m(2)): 33.8 +/- 0.9] volunteers with insulin concentrations >12 mU/L completed the study. Weight loss (LF-HP group, 9.7 +/- 1.1 kg; HF-SP group, 10.2 +/- 1.4 kg; P = 0.78) and fat loss were not significantly different between diet groups even though the subjects desired less to eat after the LF-HP meal (P = 0.02). The decrease in resting energy expenditure was not significantly different between diet groups (LF-HP, -342 +/- 185 kJ/d; HF-SP, -349 +/- 220 kJ/d). The decrease in the thermic effect of feeding with weight loss was smaller in the LF-HP group than in the HF-SP group (-0.3 +/- 1.0% compared with -3.6 +/- 0.7%; P = 0.014). Glucose and insulin responses to test meals improved after weight loss (P loss and the improvements in insulin resistance and cardiovascular disease risk factors did not differ significantly between the 2 diets, and neither diet had any detrimental effects on bone turnover or renal function.

  17. Lymphedema as a Cancer Treatment Side Effect

    Science.gov (United States)

    ... Considerations How Cancer is Treated Side Effects Dating, Sex, and Reproduction Advanced Cancer For Children For Teens For Young Adults For Older Adults Prevention and Healthy Living Cancer.Net Videos Coping With Cancer Research and Advocacy Survivorship Blog ...

  18. Thermo-Mechanical Calculations of Hybrid Rotary Friction Welding at Equal Diameter Copper Bars and Effects of Essential Parameters on Dependent Special Variables

    International Nuclear Information System (INIS)

    Parsa, M. H.; Davari, H.; Hadian, A. M.; Ahmadabadi, M. Nili

    2007-01-01

    Hybrid Rotary Friction Welding is a modified type of common rotary friction welding processes. In this welding method parameters such as pressure, angular velocity and time of welding control temperature, stress, strain and their variations. These dependent factors play an important rule in defining optimum process parameters combinations in order to improve the design and manufacturing of welding machines and quality of welded parts. Thermo-mechanical simulation of friction welding has been carried out and it has been shown that, simulation is an important tool for prediction of generated heat and strain at the weld interface and can be used for prediction of microstructure and evaluation of quality of welds. For simulation of Hybrid Rotary Friction Welding, a commercial finite element program has been used and the effects of pressure and rotary velocity of rotary part on temperature and strain variations have been investigated

  19. Thermo-Mechanical Calculations of Hybrid Rotary Friction Welding at Equal Diameter Copper Bars and Effects of Essential Parameters on Dependent Special Variables

    Science.gov (United States)

    Parsa, M. H.; Davari, H.; Hadian, A. M.; Ahmadabadi, M. Nili

    2007-05-01

    Hybrid Rotary Friction Welding is a modified type of common rotary friction welding processes. In this welding method parameters such as pressure, angular velocity and time of welding control temperature, stress, strain and their variations. These dependent factors play an important rule in defining optimum process parameters combinations in order to improve the design and manufacturing of welding machines and quality of welded parts. Thermo-mechanical simulation of friction welding has been carried out and it has been shown that, simulation is an important tool for prediction of generated heat and strain at the weld interface and can be used for prediction of microstructure and evaluation of quality of welds. For simulation of Hybrid Rotary Friction Welding, a commercial finite element program has been used and the effects of pressure and rotary velocity of rotary part on temperature and strain variations have been investigated.

  20. Spatio-Temporal Variation in Effects of Upwelling on the Fatty Acid Composition of Benthic Filter Feeders in the Southern Benguela Ecosystem: Not All Upwelling Is Equal.

    Directory of Open Access Journals (Sweden)

    Eleonora Puccinelli

    Full Text Available Variability in mesoscale nearshore oceanographic conditions plays an important role in the distribution of primary production and food availability for intertidal consumers. Advection of nutrient rich waters by upwelling usually allows the proliferation of diatoms, later replaced by dinoflagellates. We examined upwelling effects on the fatty acid (FA signature of a benthic intertidal filter feeder to identify its response to pulsed variability in food availability. The study took place in two contrasting seasons and at two upwelling and two non-upwelling sites interspersed within the southern Benguela upwelling system of South Africa. We investigated the FA composition of the adductor muscles and gonads of the mussel Mytilus galloprovincialis to assess how FA are apportioned to the different tissues and whether this changes between upwelling and non-upwelling conditions. In situ temperature loggers used to identify upwelling conditions at the four sites indicated that such events occurred only at the upwelling centres and only in summer. Tissues differed strongly, with gonads presenting a higher proportion of essential FAs. This could reflect the faster turnover rate of gonad tissue or preferential retention of specific FA for reproductive purposes. FA composition did not vary as a direct function of upwelling, but there were strong dissimilarities among sites. Upwelling influenced mussel diets at one upwelling site while at the other, the expected signature of upwelling was displaced downstream of the core of upwelling. Condition Index (CI and Gonad Index (GI differed among sites and were not influenced by upwelling, with GI being comparable among sites. In addition, FA proportions were consistent among sites, indicating similar food quality and quantity over time and under upwelling and non-upwelling conditions. This suggests that the influence of upwelling on the west coast of South Africa is pervasive and diffuse, rather than discrete; while

  1. Effective operator treatment of the Lipkin model

    International Nuclear Information System (INIS)

    Abraham, K.J.; Vary, J.P.

    2004-01-01

    We analyze the Lipkin model in the strong coupling limit using effective operator techniques. We present both analytical and numerical results for low energy effective Hamiltonians. We investigate the reliability of various approximations used to simplify the nuclear many body problem, such as the cluster approximation. We demonstrate, in explicit examples, certain limits to the validity of the cluster approximation but caution that these limits may be particular to this model where the interactions are of unlimited range

  2. Strategies for maximizing clinical effectiveness in the treatment of schizophrenia.

    Science.gov (United States)

    Tandon, Rajiv; Targum, Steven D; Nasrallah, Henry A; Ross, Ruth

    2006-11-01

    The ultimate clinical objective in the treatment of schizophrenia is to enable affected individuals to lead maximally productive and personally meaningful lives. As with other chronic diseases that lack a definitive cure, the individual's service/recovery plan must include treatment interventions directed towards decreasing manifestations of the illness, rehabilitative services directed towards enhancing adaptive skills, and social support mobilization aimed at optimizing function and quality of life. In this review, we provide a conceptual framework for considering approaches for maximizing the effectiveness of the array of treatments and other services towards promoting recovery of persons with schizophrenia. We discuss pharmacological, psychological, and social strategies that decrease the burden of the disease of schizophrenia on affected individuals and their families while adding the least possible burden of treatment. In view of the multitude of treatments necessary to optimize outcomes for individuals with schizophrenia, effective coordination of these services is essential. In addition to providing best possible clinical assessment and pharmacological treatment, the psychiatrist must function as an effective leader of the treatment team. To do so, however, the psychiatrist must be knowledgeable about the range of available services, must have skills in clinical-administrative leadership, and must accept the responsibility of coordinating the planning and delivery of this multidimensional array of treatments and services. Finally, the effectiveness of providing optimal individualized treatment/rehabilitation is best gauged by measuring progress on multiple effectiveness domains. Approaches for efficient and reliable assessment are discussed.

  3. A model to describe potential effects of chemotherapy on critical radiobiological treatments

    International Nuclear Information System (INIS)

    Rodríguez-Pérez, D.; Desco, M.M.; Antoranz, J.C.

    2016-01-01

    Although chemo- and radiotherapy can annihilate tumors on their own. they are also used in coadjuvancy: improving local effects of radiotherapy using chemotherapy as a radiosensit.izer. The effects of radiotherapy are well described by current radiobiological models. The goal of this work is to describe a discrete radiotherapy model, that has been previously used describe high radiation dose response as well as unusual radio-responses of some types of tumors (e.g. prostate cancer), to obtain a model of chemo+radiotherapy that can describe how the outcome of their combination is a more efficient removal of the tumor. Our hypothesis is that, although both treatments haven different mechanisms, both affect similar key points of cell metabolism and regulation, that lead to cellular death. Hence, we will consider a discrete model where chemotherapy may affect a fraction of the same targets destroyed by radiotherapy. Although radiotherapy reaches all cells equally, chemotherapy diffuses through a tumor attaining lower concentration in its center and higher in its surface. With our simulations we study the enhanced effect of combined therapy treatment and how it depends on the tissue critical parameters (the parameters of the lion-extensive radiobiological model), the number of “targets” aimed at by chemotherapy, and the concentration and diffusion rate of the drug inside the tumor. The results show that an equivalent, cliemo-radio-dose can be computed that allows the prediction of the lower radiation dose that causes the same effect than a radio-only treatment. (paper)

  4. A model to describe potential effects of chemotherapy on critical radiobiological treatments

    Science.gov (United States)

    Rodríguez-Pérez, D.; Desco, M. M.; Antoranz, J. C.

    2016-08-01

    Although chemo- and radiotherapy can annihilate tumors on their own. they are also used in coadjuvancy: improving local effects of radiotherapy using chemotherapy as a radiosensit.izer. The effects of radiotherapy are well described by current radiobiological models. The goal of this work is to describe a discrete radiotherapy model, that has been previously used describe high radiation dose response as well as unusual radio-responses of some types of tumors (e.g. prostate cancer), to obtain a model of chemo+radiotherapy that can describe how the outcome of their combination is a more efficient removal of the tumor. Our hypothesis is that, although both treatments haven different mechanisms, both affect similar key points of cell metabolism and regulation, that lead to cellular death. Hence, we will consider a discrete model where chemotherapy may affect a fraction of the same targets destroyed by radiotherapy. Although radiotherapy reaches all cells equally, chemotherapy diffuses through a tumor attaining lower concentration in its center and higher in its surface. With our simulations we study the enhanced effect of combined therapy treatment and how it depends on the tissue critical parameters (the parameters of the lion-extensive radiobiological model), the number of “targets” aimed at by chemotherapy, and the concentration and diffusion rate of the drug inside the tumor. The results show that an equivalent, cliemo-radio-dose can be computed that allows the prediction of the lower radiation dose that causes the same effect than a radio-only treatment.

  5. Fast Adaptive Blind MMSE Equalizer for Multichannel FIR Systems

    Directory of Open Access Journals (Sweden)

    Abed-Meraim Karim

    2006-01-01

    Full Text Available We propose a new blind minimum mean square error (MMSE equalization algorithm of noisy multichannel finite impulse response (FIR systems, that relies only on second-order statistics. The proposed algorithm offers two important advantages: a low computational complexity and a relative robustness against channel order overestimation errors. Exploiting the fact that the columns of the equalizer matrix filter belong both to the signal subspace and to the kernel of truncated data covariance matrix, the proposed algorithm achieves blindly a direct estimation of the zero-delay MMSE equalizer parameters. We develop a two-step procedure to further improve the performance gain and control the equalization delay. An efficient fast adaptive implementation of our equalizer, based on the projection approximation and the shift invariance property of temporal data covariance matrix, is proposed for reducing the computational complexity from to , where is the number of emitted signals, the data vector length, and the dimension of the signal subspace. We then derive a statistical performance analysis to compare the equalization performance with that of the optimal MMSE equalizer. Finally, simulation results are provided to illustrate the effectiveness of the proposed blind equalization algorithm.

  6. Fibromyalgia Syndrome in Need of Effective Treatments

    Science.gov (United States)

    Tsilioni, Irene; Arbetman, Lauren; Panagiotidou, Smaro; Stewart, Julia M.; Gleason, Rae M.; Russell, Irwin J.

    2015-01-01

    Fibromyalgia syndrome (FMS) is a chronic, idiopathic condition of widespread musculoskeletal pain, affecting primarily women. It is clinically characterized by chronic, nonarticular pain and a heightened response to pressure along with sleep disturbances, fatigue, bowel and bladder abnormalities, and cognitive dysfunction. The diagnostic criteria have changed repeatedly, and there is neither a definitive pathogenesis nor reliable diagnostic or prognostic biomarkers. Clinical and laboratory studies have provided evidence of altered central pain pathways. Recent evidence suggests the involvement of neuroinflammation with stress peptides triggering the release of neurosenzitizing mediators. The management of FMS requires a multidimensional approach including patient education, behavioral therapy, exercise, and pain management. Here we review recent data on the pathogenesis and propose new directions for research and treatment. PMID:26306765

  7. Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects

    DEFF Research Database (Denmark)

    Vilsbøll, Tina; Krarup, Thure; Madsbad, Sten

    2003-01-01

    was to evaluate this. Eight healthy male volunteers (mean age: 23 (range 20-25) years; mean body mass index: 22.2 (range 19.3-25.4) kg/m2) participated in studies involving stepwise glucose clamping at fasting plasma glucose levels and at 6 and 7 mmol/l. Physiological amounts of either GIP (1.5 pmol/kg/min), GLP......-1(7-36)amide (0.33 pmol/kg/min) or saline were infused for three periods of 30 min at each glucose level, with 1 h "washout" between the infusions. On a separate day, a standard meal test (566 kcal) was performed. During the meal test, peak insulin concentrations were observed after 30 min...... and amounted to 223+/-27 pmol/l. Glucose+saline infusions induced only minor increases in insulin concentrations. GLP-1 and GIP infusions induced significant and similar increases at fasting glucose levels and at 6 mmol/l. At 7 mmol/l, further increases were seen, with GLP-1 effects exceeding those of GIP...

  8. The oral adverse effects of isotretinoin treatment in acne vulgaris ...

    African Journals Online (AJOL)

    Background: Isotretinoin is the most effective therapy to treat severe acne vulgaris and its systemic adverse effects have been well documented, but little is known on dental side effects over the course of treatment. Objectives: This prospective case-control study aimed to evaluate the oral adverse effects of isotretinoin in ...

  9. Effectiveness of cryotherapy treatment for cervical intraepithelial neoplasia.

    Science.gov (United States)

    Luciani, Silvana; Gonzales, Miguel; Munoz, Sergio; Jeronimo, Jose; Robles, Sylvia

    2008-05-01

    To assess the effectiveness of cryotherapy treatment delivered by general practitioners in primary care settings, as part of a screen-and-treat approach for cervical cancer prevention. Women aged between 25 and 49 years residing in San Martin, Peru, who were positive on visual inspection screening were treated, if eligible, with cryotherapy following biopsy. At 12 months post cryotherapy treatment the participants were evaluated for treatment effectiveness and examined by visual inspection and Papanicolaou test and, if positive, referred to a gynecologist for colposcopy and biopsy. Cryotherapy treatment was performed for 1398 women; of these, 531 (38%) had a histology result of cervical intraepithelial neoplasia (CIN). Cryotherapy effectively cured CIN in 418 (88%) women, including 49 (70%) women with a baseline diagnosis of CIN 3. Cryotherapy is an effective treatment for cervical precancerous lesions; it can easily be administered by general practitioners in primary care settings following visual inspection screening.

  10. Equality in sexual health promotion: a systematic review of effective interventions for black and minority ethnic men who have sex with men

    Directory of Open Access Journals (Sweden)

    Julie Fish

    2016-08-01

    Full Text Available Abstract Background Over the past decade, new diagnoses of HIV have increased eightfold among men who have sex with men (MSM of other or of mixed ethnicity in the UK. Yet there is little intervention research on HIV among black and minority ethnic (BME MSM. This article aimed to identify effective HIV and sexual health prevention strategies for BME MSM. Methods We searched three databases PubMed, Scopus and PsychInfo using a combination of search terms: MSM or men who have sex with men and women (MSMW; Black and Minority Ethnic; HIV or sexual health; and evaluation, intervention, program* or implementation. We identified a total of 19 studies to include in the review including those which used randomised control, pre/post-test and cross-sectional design; in addition, we included intervention development studies. Results A total of 12 studies reported statistically significant results in at least one of the behavioural outcomes assessed; one study reported significant increases in HIV knowledge and changes in safer sex practices. In 10 studies, reductions were reported in unprotected anal intercourse (UAI, number of sexual partners, or in both of these measures. Six out of the 13 studies reported reductions in UAI; while seven reported reductions in number of sexual partners. Seven were intervention development studies. Conclusions Research into the mechanisms and underpinnings of future sexual health interventions is urgently needed in order to reduce HIV and other sexually transmitted infection (STI among UK BME MSM. The design of interventions should be informed by the members of these groups for whom they are targeted to ensure the cultural and linguistic sensitivity of the tools and approaches generated.

  11. Alternative inactivated poliovirus vaccines adjuvanted with Quillaja brasiliensis or Quil-a saponins are equally effective in inducing specific immune responses.

    Directory of Open Access Journals (Sweden)

    Fernanda de Costa

    Full Text Available Inactivated polio vaccines (IPV have an important role at the final stages of poliomyelitis eradication programs, reducing the risks associated with the use of attenuated polio vaccine (OPV. An affordable option to enhance vaccine immunogenicity and reduce costs of IPV may be the use of an effective and renewable adjuvant. In the present study, the adjuvant activity of aqueous extract (AE and saponin fraction QB-90 from Quillaja brasiliensis using poliovirus antigen as model were analyzed and compared to a preparation adjuvanted with Quil-A, a well-known saponin-based commercial adjuvant. Experimental vaccines were prepared with viral antigen plus saline (control, Quil-A (50 µg, AE (400 µg or QB-90 (50 µg. Sera from inoculated mice were collected at days 0, 28, 42 and 56 post-inoculation of the first dose of vaccine. Serum levels of specific IgG, IgG1 and IgG2a were significantly enhanced by AE, QB-90 and Quil-A compared to control group on day 56. The magnitude of enhancement was statistically equivalent for QB-90 and Quil-A. The cellular response was evaluated through DTH and analysis of IFN-γ and IL-2 mRNA levels using in vitro reestimulated splenocytes. Results indicated that AE and QB-90 were capable of stimulating the generation of Th1 cells against the administered antigen to the same extent as Quil-A. Mucosal immune response was enhanced by the vaccine adjuvanted with QB-90 as demonstrated by increases of specific IgA titers in bile, feces and vaginal washings, yielding comparable or higher titers than Quil-A. The results obtained indicate that saponins from Q. brasiliensis are potent adjuvants of specific cellular and humoral immune responses and represent a viable option to Quil-A.

  12. When Gender Identity Doesn't Equal Sex Recorded at Birth: The Role of the Laboratory in Providing Effective Healthcare to the Transgender Community.

    Science.gov (United States)

    Goldstein, Zil; Corneil, Trevor A; Greene, Dina N

    2017-08-01

    Transgender is an umbrella term used to describe individuals who identify with a gender incongruent to or variant from their sex recorded at birth. Affirming gender identity through a variety of social, medical, and surgical interventions is critical to the mental health of transgender individuals. In recent years, awareness surrounding transgender identities has increased, which has highlighted the health disparities that parallel this demographic. These disparities are reflected in the experience of transgender patients and their providers when seeking clinical laboratory services. Little is known about the effect of gender-affirming hormone therapy and surgery on optimal laboratory test interpretation. Efforts to diminish health disparities encountered by transgender individuals and their providers can be accomplished by increasing social and clinical awareness regarding sex/gender incongruence and gaining insight into the physiological manifestations and laboratory interpretations of gender-affirming strategies. This review summarizes knowledge required to understand transgender healthcare including current clinical interventions for gender dysphoria. Particular attention is paid to the subsequent impact of these interventions on laboratory test utilization and interpretation. Common nomenclature and system barriers are also discussed. Understanding gender incongruence, the clinical changes associated with gender transition, and systemic barriers that maintain a gender/sex binary are key to providing adequate healthcare to transgender community. Transgender appropriate reference interval studies are virtually absent within the medical literature and should be explored. The laboratory has an important role in improving the physiological understanding, electronic medical system recognition, and overall social awareness of the transgender community. © 2017 American Association for Clinical Chemistry.

  13. 49 CFR 236.792 - Reservoir, equalizing.

    Science.gov (United States)

    2010-10-01

    ... Reservoir, equalizing. An air reservoir connected with and adding volume to the top portion of the equalizing piston chamber of the automatic brake valve, to provide uniform service reductions in brake pipe...

  14. Analysis 1: SDG5, gender equal fisheries

    OpenAIRE

    Williams, Meryl J.

    2017-01-01

    What are the challenges in the path of achieving gender equality in fisheries and what should our priorities be? This article tries to identify these in the context of SDG 5, the Sustainable Development Goal on gender equality.

  15. 76 FR 53807 - Women's Equality Day, 2011

    Science.gov (United States)

    2011-08-29

    ... States to celebrate the achievements of women and recommit ourselves to the goal of gender equality in... Vol. 76 Monday, No. 167 August 29, 2011 Part IV The President Proclamation 8699--Women's Equality...

  16. 77 FR 52583 - Women's Equality Day, 2012

    Science.gov (United States)

    2012-08-29

    ... celebrate the achievements of women and recommit to realizing gender equality in this country. [[Page 52586... Equality Day, 2012 #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 77 , No. 168...

  17. The neural bases for valuing social equality.

    Science.gov (United States)

    Aoki, Ryuta; Yomogida, Yukihito; Matsumoto, Kenji

    2015-01-01

    The neural basis of how humans value and pursue social equality has become a major topic in social neuroscience research. Although recent studies have identified a set of brain regions and possible mechanisms that are involved in the neural processing of equality of outcome between individuals, how the human brain processes equality of opportunity remains unknown. In this review article, first we describe the importance of the distinction between equality of outcome and equality of opportunity, which has been emphasized in philosophy and economics. Next, we discuss possible approaches for empirical characterization of human valuation of equality of opportunity vs. equality of outcome. Understanding how these two concepts are distinct and interact with each other may provide a better explanation of complex human behaviors concerning fairness and social equality. Copyright © 2014 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.

  18. Promoting Racial Equality in the Nursing Curriculum.

    Science.gov (United States)

    Foolchand, M. K.

    1995-01-01

    Equality in nursing education and the profession can be promoted in the following ways: a working policy on racism and equal opportunities; curriculum content that explores stereotypes, values, attitudes, and prejudices; and multicultural health research, education, and promotion. (SK)

  19. Equal Access Initiative HIV/AIDS Information Resources from NLM

    Energy Technology Data Exchange (ETDEWEB)

    Templin-Branner W. and N. Dancy

    2010-09-11

    The Equal Access Initiative: HIV/AIDS Information Resources from the National Library of Medicine training is designed specifically for the National Minority AIDS Council 2010 Equal Access Initiative (EAI) Computer Grants Program awardees to provide valuable health information resources from the National Library of Medicine and other reliable sources to increase awareness of the wealth of treatment information and educational materials that are available on the Internet and to improve prevention and treatment education for their clients. These resources will also meet the needs of community-based

  20. Effect of Discontinuous Ultrasonic Treatment on Mechanical Properties and Microstructure of Cast Al413-SiCnp Nanocomposites

    Directory of Open Access Journals (Sweden)

    M.R. Dehnavi

    2015-05-01

    Full Text Available Effects of discontinuous ultrasonic treatment on the microstructure, nanoparticle distribution, and mechanical properties of cast Al413-SiCnp nanocomposites were studied. The results showed that discontinuous ultrasonic treatment was more effective in improving the mechanical properties of the cast nanocomposites than the equally timed continuous treatment. The yield and ultimate tensile strengths of Al413-2%SiCnp nanocomposites discontinuously treated for two 20 minute periods increased by about 126% and 100% compared to those of the monolithic sample, respectively. These improvements were about 107% and 94% for the nanocomposites continuously treated for a single 40 minute period. The improvement in the mechanical properties was associated with severe refinement of the microstructure, removal of the remaining gas layers on the particles surfaces, more effective fragmentation of the remaining agglomerates as well as improved wettability and distribution of the reinforcing particles during the first stage of solidification.

  1. Effective physical treatment for chronic low back pain.

    Science.gov (United States)

    Maher, C G

    2004-01-01

    It is now feasible to adopt an evidence-based approach when providing physical treatment for patients with chronic LBP. A summary of the efficacy of a range of physical treatments is provided in Table 1. The evidence-based primary care options are exercise, laser, massage, and spinal manipulation; however, the latter three have small or transient effects that limit their value as therapies for chronic LBP. In contrast, exercise produces large reductions in pain and disability, a feature that suggests that exercise should play a major role in the management of chronic LBP. Physical treatments, such as acupuncture, backschool, hydrotherapy, lumbar supports, magnets, TENS, traction, ultrasound, Pilates therapy, Feldenkrais therapy, Alexander technique, and craniosacral therapy are either of unknown value or ineffective and so should not be considered. Outside of primary care, multidisciplinary treatment or functional restoration is effective; however, the high cost probably means that these programs should be reserved for patients who do not respond to cheaper treatment options for chronic LBP. Although there are now effective treatment options for chronic LBP, it needs to be acknowledged that the problem of chronic LBP is far from solved. Though treatments can provide marked improvements in the patient's condition, the available evidence suggests that the typical chronic LBP patient is left with some residual pain and disability. Developing new, more powerful treatments and refining the current group of known effective treatments is the challenge for the future.

  2. Equality in the Framework of Justice

    OpenAIRE

    Aşik, Kübra

    2015-01-01

    This thesis assesses the relation between equality and justice by exploring and identifying the relation between equality and justice in Rawls's theory of justice, Sandel's communitarian account of Justice and Sen's capability approach. And these accounts of justice are evaluated from an egalitarian point of view. The main argument defended in the thesis is that justice requires equality. Accordingly, these three accounts of justice are evaluated by taking their understanding of equality into...

  3. Recidivism after treatment in a forensic youth-psychiatric setting: the effect of treatment characteristics

    NARCIS (Netherlands)

    van der Put, C.E.; Asscher, J.J.; Stams, G.J.J.M.; van der Laan, P.H.; Breuk, R.; Jongman, E.; Doreleijers, T.

    2013-01-01

    The aim of this study was to examine the effect of treatment characteristics on recidivism in a forensic youth-psychiatric outpatient clinic. The treatment offered comprised functional family therapy (FFT), individual cognitive behavioural therapy (CBT), or CBT in combination with parent training.

  4. Effective treatment for malignant mediastinal teratoma.

    Science.gov (United States)

    Parker, D; Holford, C P; Begent, R H; Newlands, E S; Rustin, G J; Makey, A R; Bagshawe, K D

    1983-12-01

    Primary malignant mediastinal teratoma is a rare tumour previously regarded as inevitably fatal. In a series of eight male patients with a mean age of 24 years five remain alive and well. All patients showed raised serum concentrations of human chorionic gonadotrophin or alpha fetoprotein. The patients were treated with intermittent combination chemotherapy that included cisplatin. Six patients responded to chemotherapy with a fall in human chorionic gonadotrophin or alpha fetoprotein to near normal levels and they then had radical excision of the remaining tumour. Living malignant tumour was found in four of the specimens and these patients received postoperative chemotherapy. One patient died after eight months and the remaining five patients are alive and well 13-136 months after the start of treatment. The two patients who did not undergo surgery died at one month and 15 months. Intermittent combination chemotherapy and carefully timed radical excision of these tumours would appear to have produced better results than have been reported in other series.

  5. Office of Diversity Management and Equal Opportunity

    Science.gov (United States)

    Opportunity Office of Diversity Management and Equal Opportunity Home About ODMEO Leadership Documents News Skip to main content (Press Enter). Toggle navigation Office of Diversity Management and Equal Opportunity Search Search ODMEO: Search Search ODMEO: Search Office of Diversity Management and Equal

  6. Transforming equality logic to propositional logic

    NARCIS (Netherlands)

    Zantema, H.; Groote, J.F.

    2003-01-01

    Abstract We investigate and compare various ways of transforming equality formulas to propositional formulas, in order to be able to solve satisfiability in equality logic by means of satisfiability in propositional logic. We propose equality substitution as a new approach combining desirable

  7. Sex, Money and the Equal Pay Act

    Science.gov (United States)

    Feldman, Edwin B.

    1973-01-01

    Institutions who justify a wage differential between male and female custodians on the basis that women typically do the lighter work, and men the heavier, can find themselves in trouble. The Equal Pay Act of 1963 requires that men and women get the same pay for equal work -- and all custodial work is substantially equal to the Labor Department.…

  8. Does 0.999... Really Equal 1?

    Science.gov (United States)

    Norton, Anderson; Baldwin, Michael

    2012-01-01

    This article confronts the issue of why secondary and post-secondary students resist accepting the equality of 0.999... and 1, even after they have seen and understood logical arguments for the equality. In some sense, we might say that the equality holds by definition of 0.999..., but this definition depends upon accepting properties of the real…

  9. Individualized Sex Equality in Transforming Finnish Academia

    Science.gov (United States)

    Lätti, Johanna

    2017-01-01

    This article examines the equality agenda in the context of Finnish university reform in the 21st century. In Finland, the academic regime went through an organizational transformation after the Universities Act in 2009. However, little attention has been paid to the questions of sex or equality. Since the policy influences on equality in…

  10. Improved treatment of radiation effects on the skin

    International Nuclear Information System (INIS)

    Wandl, E.O.; Kaercher, K.H.; Wandl-Hainberger, I.

    1985-01-01

    The treatment concept developed by K.H. Kaercher was extended by a therapy using Elasten S cream. In the course of a highvoltage therapy using fast electrons or cobalt-60, interesting aspects in the treatment and progression of the radiation reactions of the skin were established. The dermato-therapeutic principles layed down by K.H. Kaercher with the treatment palette used hitherto, have without doubt invariably proven their value. The exclusive powder treatment, however, may be made more practical by application of the new treatment cream in accordance with the intervals in radiation treatment or as a basic treatment towards the end of therapy. Furthermore it is ideally suited for the care and after-treatment of skin, strained by radiation. It reduces considerably the remaining visible radiation reactions. The treatment with powder and emulsion has for more than 10 years proven effective. After the excellent results of the new cream during radiation treatment, additional positive effects are expected in a long-term trial which will be reported on separately. (orig.) [de

  11. Effect of blind treatment on stone disease.

    Science.gov (United States)

    Fazil Marickar, Y M; Salim, Abiya; Vijay, Adarsh

    2010-06-01

    Most of the drugs administered to stone patients appear to be inappropriate and doing more harm than good to the patients. The objective of this paper is to identify the prevalence of blind chemotherapy among the stone patients and find out the real indication for the drugs administered. Patients who attended the stone clinic for the first time were interviewed to find out what drugs they had been taking before the attendance at the stone clinic. 350 patients consuming specific drugs relevant to stone formation at least for a period of 15 days were selected for a detailed assessment. The type of drug consumed, the dose, the duration, the side effects, compliance rate and effect on stone disease were assessed. The biochemical profile of the patients was assessed to identify the role of the therapeutic modalities utilised. Conclusions regarding the utility of drugs in the process of stone formation were made. The values were compared with those of patients not on medication and considering laboratory standards. Of the 350 patients studied, 96 patients were consuming potassium citrate in different doses, 50 were consuming allopurinol, 44 cystone, 27 potassium citrate + magnesium, 25 calcury, 24 rowatinex, 21 ayurvedic drugs, 17 dystone, 17 homeopathic medicines and 17 other drugs. The longest duration of compliance was for cystone-2.5 years. All other drugs were stopped by the patients themselves due to recurrence of symptoms. As much as 93% of the patients did not feel that there was any significant relief of symptoms. The side effects which prompted the patients to stop medicine were gastro intestinal upset, particularly with potassium citrate, rowatinex and potassium citrate + magnesium combination. The relevant biochemical changes noted were increased urinary citrate levels in patients consuming potassium citrate alone or in combination with magnesium. Serum uric acid was within normal limits in patients consuming allopurinol. Urine uric acid levels were also

  12. Predicting the effect of psychoeducational group treatment for hypochondriasis.

    NARCIS (Netherlands)

    Buwalda, F.M.; Bouman, T.K.

    2008-01-01

    Both individual cognitive-behavioural therapy and short-term psychoeducational courses have shown to be effective in reducing hypochondriacal complaints. However, it is unknown which patients benefit from treatment. The aim of the present study is to explore which variables predict treatment outcome

  13. Comparative Study of Pre-Germination Treatments and their Effects ...

    African Journals Online (AJOL)

    FIRST LADY

    of leaves (10.05) respectively. Pre-germination treatments of seeds soaked in running water (SRW) for 24 hours were found to be more effective in seedlings growth and biomass production. Keywords: Tectona grandis, pre-germination treatment, seed dormancy, seedling growth. Introduction. Tectona grandis is one of the ...

  14. Moringa extracts used in sugarcane juice treatment and effects on ...

    African Journals Online (AJOL)

    The objective of this study was to evaluate the effects of sugarcane juice treatment using Moringa oleifera leaf and seeds extracts on ethanolic fermentation. The experiment was arranged in a split plot statistical design, with four replications. Main treatments were three sedimentation agents (synthetic polyelectrolyte, ...

  15. Effects of Hot Water Treatment and Temperature on Seedling ...

    African Journals Online (AJOL)

    An experiment was conducted at the Faculty of Agriculture, University of Maiduguri, to study the effect of hot water treatment and temperature on the morphological characteristics of Arabic gum. The experiment was laid out in a Randomized Complete Block Design in a factorial arrangement. The treatments included a ...

  16. Effect of physical treatment on Trichoderma reesei cells

    International Nuclear Information System (INIS)

    Kumakura, M.; Kaetsu, I.

    1984-01-01

    The effect of physical treatment such as freezing and gamma-ray irradiation on Trichoderma reesei cells was studied. The decrease phenomena of cellulase production, which was observed in the culture of the cells using wheat bran extract, was improved by physical treatment. (author)

  17. Mode-Specific Effects among Three Treatments for Depression.

    Science.gov (United States)

    Imber, Stanley D.; And Others

    1990-01-01

    Randomly assigned 250 depressed outpatients to interpersonal psychotherapy, cognitive-behavioral therapy, imipramine plus clinical management, or pill placebo plus clinical management treatments. All treatments demonstrated significant symptom reduction with few differences in general outcomes. None of the therapies produced consistent effects on…

  18. Nonthermal effects in thermal treatment applications of nonionizing irradiation

    Science.gov (United States)

    Thomsen, Sharon

    2005-04-01

    Several non-thermal factors influence the primary and secondary effects of interstitial thermal treatments using various types of non-ionizing irradiation. Recognition and understanding of the influences of these various factors are important in choice of energy source, the configuration of the application instrument and the design of treatments.

  19. Effect of heat treatment on structure and magnetic properties

    Indian Academy of Sciences (India)

    Fe46Co35Ni19/CNTs nanocomposites have been prepared by an easy two-step route including adsorption and heat treatment processes. We investigated the effect of heat treatment conditions on structure, morphology, nanoparticle sizes and magnetic properties of the Fe46Co35Ni19 alloy nanoparticles attached on the ...

  20. Effect of heat treatment temperature on binder thermal conductivities

    International Nuclear Information System (INIS)

    Wagner, P.

    1975-12-01

    The effect of heat treatment on the thermal conductivities of a pitch and a polyfurfuryl alcohol binder residue was investigated. Graphites specially prepared with these two binders were used for the experiments. Measured thermal conductivities were treated in terms of a two-component system, and the binder thermal conductivities were calculated. Both binder residues showed increased thermal conductivity with increased heat treatment temperature

  1. Effects of thermal treatments and germination on physico-chemical ...

    African Journals Online (AJOL)

    Certain physico-chemical properties including viscoelasticity, crystallinity and maltose content of corn depends on the gelatinization of starch under different treatments. Three different treatments were performed; boiling in water, steam heating, and germination. The effects of gelatinization on viscoelastic property of corn ...

  2. Effect of time on dyeing wastewater treatment

    Science.gov (United States)

    Ye, Tingjin; Chen, Xin; Xu, Zizhen; Chen, Xiaogang; Shi, Liang; He, Lingfeng; Zhang, Yongli

    2018-03-01

    The preparation of carboxymethylchitosan wrapping fly-ash adsorbent using high temperature activated fly ash and sodium carboxymethyl chitosan (CWF), as with the iron-carbon micro-electrolysis process simulation and actual printing and dyeing wastewater. The effects of mixing time and static time on decolorization ratio, COD removing rate and turbidness removing rate were investigated. The experimental results show that the wastewater stirring times on the decolorization rate and COD removal rate and turbidity removal rate influence, with increasing of the stirring time, three showed a downward trend, and reached the peak at 10 min time; wastewater time on the decolorization ratio and COD removing efficiency and turbidness removing rate influence, along with standing time increase, three who declined and reached the maximum in 30min time.

  3. The policy on gender equality in Denmark

    DEFF Research Database (Denmark)

    Agustin, Lise Rolandsen

    The briefing paper describes current Danish policies, practices and legislation within the area of gender equality. It addresses economic independence, reconciliation policies, participation in decision-making, gender-based violence and trafficking, gender stereotypes, and gender equality...... in development policies. The former liberal-conservative government (2001-2011) has focused on equal opportunities, gender equality as a means to economic growth, voluntary measures and freedom of choice. Increased attention has been paid in recent years to ethnic minorities and to men’s role in gender equality....

  4. Neuroimaging in aphasia treatment research: Standards for establishing the effects of treatment

    Science.gov (United States)

    Kiran, Swathi; Ansaldo, Ana; Bastiaanse, Roelien; Cherney, Leora R.; Howard, David; Faroqi-Shah, Yasmeen; Meinzer, Marcus; Thompson, Cynthia K

    2012-01-01

    The goal of this paper is to discuss experimental design options available for establishing the effects of treatment in studies that aim to examine the neural mechanisms associated with treatment-induced language recovery in aphasia, using functional magnetic resonance imaging (fMRI). We present both group and single-subject experimental or case-series design options for doing this and address advantages and disadvantages of each. We also discuss general components of and requirements for treatment research studies, including operational definitions of variables, criteria for defining behavioral change and treatment efficacy, and reliability of measurement. Important considerations that are unique to neuroimaging-based treatment research are addressed, pertaining to the relation between the selected treatment approach and anticipated changes in language processes/functions and how such changes are hypothesized to map onto the brain. PMID:23063559

  5. Effects of mulching, fertilizer, seeding and seedling treatments

    African Journals Online (AJOL)

    Mgina

    Mulching treatment had an effect of increasing mortality of non-woody species and selectively favoring the ... central Tanzania where former bad land use practices ... of one or a few fast growing annual or perennial ...... Food Agric. 75: 412-.

  6. Effects of certain burning treatments on veld condition in Giant's ...

    African Journals Online (AJOL)

    Effects of certain burning treatments on veld condition in Giant's Castle Game Reserve. ... Keywords: above-ground standing crop; basal cover; burning; composition change; giant's castle game reserve; natal ... AJOL African Journals Online.

  7. Effects of palm pollen on folliculogenesis process after treatment ...

    African Journals Online (AJOL)

    Effects of palm pollen on folliculogenesis process after treatment with cyclophosphamide among rats. ... Background and purpose: Palm pollen is a good source of natural antioxidants and has a high level of health ... HOW TO USE AJOL.

  8. Prolotherapy: An Effective Treatment for Low Back Pain?

    Science.gov (United States)

    ... pain? Is prolotherapy an effective treatment for chronic low back pain? Answers from Brent A. Bauer, M.D. Prolotherapy is ... reduced pain. Studies of prolotherapy in people with low back pain have had mixed results. A combination of prolotherapy ...

  9. Brine treatment, smoking and storage techniques: their effects on the ...

    African Journals Online (AJOL)

    Journal of Food Technology in Africa ... Brine treatment, smoking and storage techniques: their effects on the microbial quality of smoked mackerel. ... off odour development, softening of the fish and positively affected personal preference.

  10. Effect of thermal treatment conditions on properties of vanadium molybdenum oxide catalyst in acrolein oxidation reaction to acrylic acid

    International Nuclear Information System (INIS)

    Gorshkova, T.P.; Tarasova, D.V.; Olen'kova, I.P.; Andrushkevich, T.V.; Nikoro, T.A.

    1984-01-01

    The effect of thermal treatment conditions (temperature and gas medium) on properties of vanadium molybdenum oxide catalyst in acrolein oxidation reaction to acrylic acid is investigated. It is shown that active and selective catalysts are formed in the course of thermal decomposition of the drying product of ammonium metavanadate and paramolybdate under the conditions ensuring the vanadium ion reduction up to tetravalent state with conservation of molybdenum oxidation degree equal to 6. It is possible to realize it either by treatment of the catalyst calcinated in the air flow at 300 deg by the reaction mixture at the activation stage or by gas-reducer flow treatment at 280 deg. Thermal treatment in the reducing medium of the oxidized catalyst does not lead to complete regeneration of its properties

  11. Regulation vs. reality in Serbia: Gender equality, economy and state

    Directory of Open Access Journals (Sweden)

    Đurić-Kuzmanović Tatjana

    2010-01-01

    Full Text Available When the Law on Equality between Sexes (2009 and the National Strategy for Improving the Position of Women and Advancing Gender Equality (2009 were adopted, after a several years of obstruction of proceedings, in Serbia normative prerequisites for the implementation of the gender equality policy and for prevention and sanctioning of all kinds of gender based discrimination were created. In this paper, the author discusses the expected effect of the implementation of the Law on Equality between sexes. In addition, the key argument which restricts its implementation and potential positive effects is explained. The context of the dominate patriarchy and the prevailing human nondevelopment in Serbia does not stimulate neither women nor men, as development actors (manager, worker, trade union, state, to act in the direction to change gender regime and to take responsibility for development of the economy and society.

  12. Women and Gender Equality in Higher Education?

    Directory of Open Access Journals (Sweden)

    Miriam E. David

    2015-02-01

    Full Text Available I look at the changes in higher education (HE and women’s lives over the last 50 years, drawing on my recent book Feminism, Gender & Universities: Politics, Passion & Pedagogies which is a life history of feminism entering academe. The Robbins Report (cmnd 2154 1963 on HE was published in the same year that I went to university. It inaugurated a process of change and educational expansion that was linked to other major social transformations, including feminism. Its effects have been widely felt such that women now participate in education and employment on unprecedented levels. Indeed, it has opened up opportunities for education and employment for women including individual and social mobility. From my study I show how it opened up opportunities for women from both middle class and working class backgrounds to be first-in-the-family to go to university. I will also argue that whilst there have been very welcome changes in education, and HE especially, such that there is a gender balance of undergraduate students in HE, this does not mean that gender equality has been achieved. Patriarchy or hegemonic masculinity in HE is still strongly felt and experienced despite women’s and feminist involvements in academe over the last 50 years. The question remains about how to transform universities to achieve genuine gender equality across all students and academics in HE.

  13. Effective antihypertensive treatment postpones renal insufficiency in diabetic nephropathy

    DEFF Research Database (Denmark)

    Parving, H H; Smidt, U M; Hommel, E

    1993-01-01

    The effect of long-term, aggressive, antihypertensive treatment on kidney function in diabetic nephropathy was studied prospectively in 11 insulin-dependent diabetic patients (mean age, 30 years). Renal function was assessed every 4 months by measurement of glomerular filtration rate (GFR) (single...... infarction (GFR, 46 mL/min/1.73 m2). Effective antihypertensive treatment postpones renal insufficiency in diabetic nephropathy....

  14. Corporate equality and equity prices: Doing well while doing good?

    OpenAIRE

    Fu, Shihe; Shan, Liwei

    2009-01-01

    Two competing hypotheses, value enhancing and value discounting, state that implementing socially responsible corporate policies can have positive or negative effects on firm value. This paper tests how a specific type of social responsibility–corporate equality–affects firm value. Corporate equality is measured by the corporate equality index (CEI). This index quantifies how companies treat their gay, lesbian, bisexual, and transgender employees, consumers, and investors. Using a sample of C...

  15. GSM Channel Equalization Algorithm - Modern DSP Coprocessor Approach

    Directory of Open Access Journals (Sweden)

    M. Drutarovsky

    1999-12-01

    Full Text Available The paper presents basic equations of efficient GSM Viterbi equalizer algorithm based on approximation of GMSK modulation by linear superposition of amplitude modulated pulses. This approximation allows to use Ungerboeck form of channel equalizer with significantly reduced arithmetic complexity. Proposed algorithm can be effectively implemented on the Viterbi and Filter coprocessors of new Motorola DSP56305 digital signal processor. Short overview of coprocessor features related to the proposed algorithm is included.

  16. Topical perfluorodecalin resolves immediate whitening reactions and allows rapid effective multiple pass treatment of tattoos.

    Science.gov (United States)

    Reddy, Kavitha K; Brauer, Jeremy A; Anolik, Robert; Bernstein, Leonard; Brightman, Lori; Hale, Elizabeth; Karen, Julie; Weiss, Elliot; Geronemus, Roy G

    2013-02-01

    Laser tattoo removal using multiple passes per session, with each pass delivered after spontaneous resolution of whitening, improves tattoo fading in a 60-minute treatment time. Our objective was to evaluate the safety and efficacy of topical perfluorodecalin (PFD) in facilitating rapid effective multiple-pass tattoo removal. In a randomized, controlled study using Q-switched ruby or Nd:YAG laser, 22 previously treated tattoos were treated with 3 passes using PFD to resolve whitening after each pass ("R0 method"). In previously untreated symmetric tattoos, seven were treated over half of the tattoo with the R20 method, and the opposite half with 4 passes using PFD (R0 method); two were treated over half with a single pass and the opposite half with 4 passes using PFD (R0 method); and six treated over half with a single pass followed by PFD and the opposite half with a single pass alone. Blinded dermatologists rated tattoo fading at 1-3 months. Optical coherence tomography (OCT) imaging of whitening was performed in two tattoos. Topical PFD clinically resolved immediate whitening reactions within a mean 5 seconds (range 3-10 seconds). Tattoos treated with the R0 method demonstrated excellent fading in an average total treatment time of 5 minutes. Tattoo areas treated with the R0 method demonstrated equal fading compared to the R20 method, and improved fading compared to a single pass method. OCT imaging of whitening demonstrated epidermal and dermal hyper-reflective "bubbles" that dissipated until absent at 9-10 minutes after PFD application, and at 20 minutes without intervention. Multiple-pass tattoo removal using PFD to deliver rapid sequential passes (R0 method) appears equally effective as the R20 method, in a total treatment time averaging 5 minutes, and more effective than single pass treatment. OCT-visualized whitening-associated "bubbles," upon treatment with PFD, resolve twice as rapidly as spontaneous resolution. Copyright © 2012 Wiley

  17. Capturing the Landauer bound through the application of a detailed Jarzynski equality for entropic memory erasure.

    Science.gov (United States)

    Das, Moupriya

    2014-12-01

    The states of an overdamped Brownian particle confined in a two-dimensional bilobal enclosure are considered to correspond to two binary values: 0 (left lobe) and 1 (right lobe). An ensemble of such particles represents bits of entropic information. An external bias is applied on the particles, equally distributed in two lobes, to drive them to a particular lobe erasing one kind of bit of information. It has been shown that the average work done for the entropic memory erasure process approaches the Landauer bound for a very slow erasure cycle. Furthermore, the detailed Jarzynski equality holds to a very good extent for the erasure protocol, so that the Landauer bound may be calculated irrespective of the time period of the erasure cycle in terms of the effective free-energy change for the process. The detailed Jarzynski equality applied to two subprocesses, namely the transition from entropic memory state 0 to state 1 and the transition from entropic memory state 1 to state 1, connects the work done on the system to the probability to occupy the two states under a time-reversed process. In the entire treatment, the work appears as a boundary effect of the physical confinement of the system not having a conventional potential energy barrier. Finally, an analytical derivation of the detailed and classical Jarzynski equality for Brownian movement in confined space with varying width has been proposed. Our analytical scheme supports the numerical simulations presented in this paper.

  18. EQUAL OPPORTUNITIES IN THE ITALIAN LABOUR MARKET

    Directory of Open Access Journals (Sweden)

    Balazs-Foldi Emese

    2015-07-01

    Full Text Available The integration of persons with disabilities and with reduced work capacity in the labour market represents one of the biggest challenges for labour market policies. The non-integration of disabled people in the labour market causes huge costs for the countries’ economy. The European Union’s aim is to transform passive social support into active support by means of labor market policy measures, to help people to obtain gainful employment and to raise employment levels of people with disabilities and with reduced work capacities. Earlier this target group has to work in the sheltered employment. But it changed from the 90’s years because of the social model of disability definition. Nowadays the main goal to help this target group integrates in the open employment. The members of European Union imagine this aim on other way. The Scandinavian countries or England prefer the equal opportunities and the personalised mainstreaming programmes and services. Other European countries, as Germany, Austria or Italy prefer the rehabilitation quota system. Thus, the labor force participation and employment rates for people with disabilities and with reduced working capacities are strong differences between the European countries. But lot of other options also influence the member of countries’ policy and employment system. Since the Amsterdam Treaty the European Union has devoted exceptional attention to the equal opportunities of disabled people, the enforcement of equal treatment, and the reduction of the dangers of discrimination, as it is, a significant part of persons with disabilities and reduced work capacity do not have a full-time job, they become unemployed two or three times more frequently than their abled-counterparts, and dispose of lower salary, therefore they need the help of their family and the community. This study examines the Italian situation. It bases on statistics on the Italian target group and provides comparisons with

  19. Modelling the effects of treatment and quarantine on measles

    Science.gov (United States)

    Beay, Lazarus Kalvein

    2018-03-01

    Treatment and quarantine are efforts to cure as well as to overcome the spread of diseases including measles. The spread of measles can be expressed by mathematical modelling in the form of nonlinear dynamical systems. In this study was conducted on the spread of measles by considering the effect of treatment and quarantine on the infected individuals. By using the basic reproduction number of the model, can be analyzed the effects of treatment and quarantine to reduce the spread of measles. Basic reproduction number of models is monotonically descreasing as treatment and quarantine increasing. Numerical simulations conducted on the analysis of the results. The results showed that treatment and quarantine was given to infected individuals who were infectious has a major influence to eliminate measles from the system.

  20. Nonvolatile memory effect of tungsten nanocrystals under oxygen plasma treatments

    International Nuclear Information System (INIS)

    Chen, Shih-Cheng; Chang, Ting-Chang; Chen, Wei-Ren; Lo, Yuan-Chun; Wu, Kai-Ting; Sze, S.M.; Chen, Jason; Liao, I.H.; Yeh, Fon-Shan

    2010-01-01

    In this work, an oxygen plasma treatment was used to improve the memory effect of nonvolatile W nanocrystal memory, including memory window, retention and endurance. To investigate the role of the oxygen plasma treatment in charge storage characteristics, the X-ray photon-emission spectra (XPS) were performed to analyze the variation of chemical composition for W nanocrystal embedded oxide both with and without the oxygen plasma treatment. In addition, the transmission electron microscopy (TEM) analyses were also used to identify the microstructure in the thin film and the size and density of W nanocrystals. The device with the oxygen plasma treatment shows a significant improvement of charge storage effect, because the oxygen plasma treatment enhanced the quality of silicon oxide surrounding the W nanocrystals. Therefore, the data retention and endurance characteristics were also improved by the passivation.

  1. Patients knowledge about side effects of orthodontic treatment

    Directory of Open Access Journals (Sweden)

    Mia Amalia

    2011-07-01

    Full Text Available Disharmonious of dental arrangement can possibly create problems for the patient, such as the masticatory function, esthetical, psychosocial, and also the increased risk of trauma and periodontal disease. These are reasons for a patient to seek orthodontic treatment. The aim of this study was to know the patient’s knowledge about the side effects possibility that they receive during orthodontic treatment. The side effects include pain experience during orthodontic treatment, the possibility of soft tissue damage, email demineralization, loss of tooth vitality, periodontal problem, root resorption, temporomandibular joint disorders, and relapse. A cross-sectional study was conducted in patients who registered at Orthodontic Department, Faculty of Dentistry, Universitas Indonesia on March-June 2009. The participants of this study were 100 patients, consist of 86 women and 14 men respectively. Twenty-seven questions about the side-effects of orthodontic treatment were used to obtain the patient’s knowledge and the result was categorized into 3 groups, good, average and poor. The result of the study showed that patient’s knowledge about the side effect of pain experience during orthodontic treatment was average and the patient’s knowledge about the possibility of soft tissue damage due to orthodontic treatment was good. However, the patient’s knowledge about the possibility of email demineralization, loss of tooth vitality, periodontal problem, root resorption, temporomandibular joint disorders and relapse due to orthodontic treatment was low.

  2. Estimation of treatment preference effects in clinical trials when some participants are indifferent to treatment choice

    Directory of Open Access Journals (Sweden)

    Stephen D. Walter

    2017-02-01

    Full Text Available Abstract Background In the two-stage randomised trial design, a randomly sampled subset of study participants are permitted to choose their own treatment, while the remaining participants are randomised to treatment in the usual way. Appropriate analysis of the data from both arms of the study allows investigators to estimate the impact on study outcomes of treatment preferences that patients may have, in addition to evaluating the usual direct effect of treatment. In earlier work, we showed how to optimise this design by making a suitable choice of the proportion of participants who should be assigned to the choice arm of the trial. However, we ignored the possibility of some participants being indifferent to the treatments under study. In this paper, we extend our earlier work to consider the analysis of two-stage randomised trials when some participants have no treatment preference, even if they are assigned to the choice arm and allowed to choose. Methods We compare alternative characterisations of the response profiles of the indifferent or undecided participants, and derive estimates of the treatment and preference effects on study outcomes. We also present corresponding test statistics for these parameters. The methods are illustrated with data from a clinical trial contrasting medical and surgical interventions. Results Expressions are obtained to estimate and test the impact of treatment choices on study outcomes, as well as the impact of the actual treatment received. Contrasts are defined between patients with stated treatment preferences and those with no preference. Alternative assumptions concerning the outcomes of undecided participants are described, and an approach leading to unbiased estimation and testing is identified. Conclusions Use of the two-stage design can provide important insights into determinants of study outcomes that are not identifiable with other designs. The design can remain attractive even in the presence of

  3. Chemistry of cost effective water treatment programme in HWP (Manuguru)

    International Nuclear Information System (INIS)

    Mohapatra, C.; Laxmana Prasad, K.

    2008-01-01

    In order to develop a water treatment programme following points must be kept in mind: Effectiveness to achieve desired water quality objectives; Compliance with regulatory requirements; Cost minimization; Safety; Easy operation and protection to equipments. Heavy Water Plant (Manuguru) laboratory has developed treatment programs to treat raw water and cooling water which satisfy the above requirements and has been in use for last several years successfully without any problem. These treatment programs have been given to other plants in Heavy Water Board for implementation. This paper describes the chemistry of the treatment program and cost minimization achieved. Further these treatments have helped the plant in achieving ΦZero Discharge and indirectly reduced the production cost. The chemistry parameters are monitored regularly to ascertain the effectiveness of these treatments. The areas where significant benefits derived are raw water treatment using polyelectrolyte instead of inorganic coagulant (alum), change over of regenerant of cation exchangers from hydrochloric acid to sulfuric acid and development of in-house cooling water treatment formulation. The advantages and cost effectiveness of these treatments are discussed in detail. Further these treatments helped the plant in achieving Zero discharge and indirectly reduced production cost of heavy water. The dosage of 3 ppm of polyelectrolyte can replace 90 ppm alum at turbidity level of 300 NTU of raw water which has resulted in cost saving of Rs. 15 - 20 Lakhs in a year besides other advantages. The changeover of regenerant from HCl to H 2 SO 4 will result in cost saving of at least Rs. 1.4 Crore a year along with other advantages. The change over of proprietary formulation to in-house formulation in cooling water treatment has resulted a saving about Rs. 11 Lakhs a year. To achieve the above objectives in a sustainable way the performance results are being monitored (author)

  4. Towards a framework for treatment effectiveness in schizophrenia

    Directory of Open Access Journals (Sweden)

    Juckel G

    2014-09-01

    Full Text Available Georg Juckel,1 Andrea de Bartolomeis,2 Philip Gorwood,3 Sergey Mosolov,4 Luca Pani,5 Alessandro Rossi,6 Julio Sanjuan7 1Department of Psychiatry, LWL-University Hospital, Ruhr-University Bochum, Bochum, Germany; 2Laboratory of Molecular Psychiatry and Unit of Treatment Resistant Psychosis, University School of Medicine of Naples Federico II, Napoli, Italy; 3Groupe Hospitalier Sainte-Anne (CMME, Paris-Descartes University, Paris, France; 4Moscow Research Institute of Psychiatry, Moscow, Russia; 5Institute of Translational Pharmacology, Italian National Research Council, Rome, Italy; 6Università de L’Aquila, L’Aquila, Italy; 7Clinic Hospital, Spanish Mental Health Network (CIBERSAM, University of Valencia, Valencia, Spain Introduction: Prompt administration of antipsychotic treatment that is adhered to is essential for the optimal treatment of schizophrenia. Many patients have benefited from the advent of second-generation antipsychotics, which can offer good symptomatic control with reduced incidence of extrapyramidal symptoms, although with higher risk of metabolic side effects. It is unsurprising that accounts as to whether first- and second-generation antipsychotics differ in their efficacy vary, since treatment effectiveness is a broad notion and difficult to define. Objectives: Numerous factors may be used to gauge treatment effectiveness and, while it has largely been defined in terms of improvements in four domains (symptoms of disease, treatment burden, disease burden, and health and wellness, the real-world clinical utility of this consensus is unclear. Therefore, this article aims to provide a framework that can aid psychiatrists in making assessments about treatment effectiveness. Methods and results: A panel of 12 psychiatrists and psychopharmacologists convened to develop and propose an accessible and globally-applicable framework for assessing the effectiveness of antipsychotic treatments in patients with schizophrenia

  5. Cost-effectiveness of root caries preventive treatments.

    Science.gov (United States)

    Schwendicke, Falk; Göstemeyer, Gerd

    2017-01-01

    With a growing number of individuals retaining their teeth lifelong, often with periodontitis-induced root surface exposure, there is the need for cost-effective management strategies for root caries lesions. The present study aimed to assess the cost-effectiveness of root caries preventive treatments. Patients were simulated over 10 years using a Markov model. Four treatments were compared: No treatment, daily 225-800ppm fluoride rinses, chlorhexidine (CHX) varnish (2×/year), silver diamine fluoride (SDF) varnish (2×/year). Data from a systematic review were submitted to network meta-analysis for inferring relative efficacies of treatments. The health outcome was years of teeth being free of root caries. A mixed public-private payer perspective within 2016 German healthcare was taken, with costs being estimated from fee item catalogues or based on market prices. Populations with different numbers of teeth and tooth-level risks were modelled. Monte-Carlo microsimulations, univariate- and probabilistic sensitivity analyses were performed. In populations with 16 teeth at risk and low tooth-level risk for root caries, providing no preventive treatment was least costly, but also least effective (130 Euro, 144 years). SDF ranked next, being more costly (180 Euro), but also more effective (151 years). Payers willing to invest 8.30 Euro per root caries-free tooth-year found SDF most cost-effective. CHX varnish and fluoride rinse were not cost-effective. In populations with more teeth and high tooth-level risk, SDF was the most effective and least costly option. Root caries preventive treatments (like SDF) are effective and might even be cost-saving in high risk populations. Application of SDF can be recommended as a cost-saving treatment for prevention of root caries in patients with high risk of root caries. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Effects of heat treatment on the radiosensitivity of Salmonellae

    International Nuclear Information System (INIS)

    Choi, E.H.; Yang, J.S.; Lee, S.R.

    1978-01-01

    When the food poisoning bacteria Salmonella enteritidis and S. typhimurium were treated with radiation (cobalt-60 γ-rays) and heat (10 minutes at 45 0 C or 50 0 C), their sterilizing effect was revealed differently depending on the order of treatments. Post-irradiation heating showed a synergistic effect whereas pre-irradiation heating revealed the opposite effect and the effects differed slightly with heating temperature. (author)

  7. Counteracting 16-QAM Optical Fiber Transmission Impairments With Iterative Turbo Equalization

    DEFF Research Database (Denmark)

    Arlunno, Valeria; Caballero Jambrina, Antonio; Borkowski, Robert

    2013-01-01

    A turbo equalization (TE) scheme based on convolutional code and normalized least mean square equalizer for coherent optical communication links is proposed and experimentally demonstrated. The proposed iterative TE technique is proved effective for counteracting polarization-division-multiplexin......A turbo equalization (TE) scheme based on convolutional code and normalized least mean square equalizer for coherent optical communication links is proposed and experimentally demonstrated. The proposed iterative TE technique is proved effective for counteracting polarization...

  8. A passive acoustic monitor of treatment effectiveness during extracorporeal lithotripsy

    International Nuclear Information System (INIS)

    Fedele, F; Coleman, A J; Thomas, K; Ryves, S; Phillips, D; Leighton, T G

    2011-01-01

    Although extracorporeal shockwave lithotripsy (ESWL) has now been in the clinic for at least three decades, there has been little advance in efforts (i) to estimate the efficacy of the treatment whilst it is in progress, or (ii) to determine the end-point of a treatment session in terms of the degree of stone fragmentation achieved. Previous in vitro experimentation and clinical trials have shown that a passive acoustic monitor has the potential to provide evidence of the effectiveness and end-point of lithotripsy. The system exploits secondary emissions generated during shock-tissue interaction, whose features depend on the quality of tissue at the beam focus. This prototype was developed into the first commercially available clinical ESWL treatment monitor (Precision Acoustic Ltd, Dorchester, UK), and a unit has been acquired and tested in the clinical routine by urologists at Guy's and St Thomas NHS Trust in March 2009. This paper critically assesses the performance of the new system for the first 25 treatments monitored. The ESWL monitor correctly predicted the treatment outcome of 15 of the 18 treatments that were followed-up clinically. In addition, it was noted that the measure of treatment effectiveness provided by the monitor after 500 shocks was predictive of the final treatment outcome (p < 0.001). This suggests that the system could be used in pre-assessment; indicating if the stone is susceptible to ESWL or if the patient should be sent for surgery.

  9. A passive acoustic monitor of treatment effectiveness during extracorporeal lithotripsy

    Energy Technology Data Exchange (ETDEWEB)

    Fedele, F; Coleman, A J [Medical Physics Department, Guy' s and St Thomas NHS Foundation Trust, Westminster Bridge Road, SE1 7EH, London (United Kingdom); Thomas, K; Ryves, S; Phillips, D [Urology Department, Guy' s and St Thomas NHS Foundation Trust, Great Maze Pond, SE1 9RT, London (United Kingdom); Leighton, T G, E-mail: fiammetta.fedele@gstt.nhs.uk [Institute of Sound and Vibration Research, University of Southampton, Highfield, S017 1BJ, Southampton (United Kingdom)

    2011-02-01

    Although extracorporeal shockwave lithotripsy (ESWL) has now been in the clinic for at least three decades, there has been little advance in efforts (i) to estimate the efficacy of the treatment whilst it is in progress, or (ii) to determine the end-point of a treatment session in terms of the degree of stone fragmentation achieved. Previous in vitro experimentation and clinical trials have shown that a passive acoustic monitor has the potential to provide evidence of the effectiveness and end-point of lithotripsy. The system exploits secondary emissions generated during shock-tissue interaction, whose features depend on the quality of tissue at the beam focus. This prototype was developed into the first commercially available clinical ESWL treatment monitor (Precision Acoustic Ltd, Dorchester, UK), and a unit has been acquired and tested in the clinical routine by urologists at Guy's and St Thomas NHS Trust in March 2009. This paper critically assesses the performance of the new system for the first 25 treatments monitored. The ESWL monitor correctly predicted the treatment outcome of 15 of the 18 treatments that were followed-up clinically. In addition, it was noted that the measure of treatment effectiveness provided by the monitor after 500 shocks was predictive of the final treatment outcome (p < 0.001). This suggests that the system could be used in pre-assessment; indicating if the stone is susceptible to ESWL or if the patient should be sent for surgery.

  10. A passive acoustic monitor of treatment effectiveness during extracorporeal lithotripsy

    Science.gov (United States)

    Fedele, F.; Thomas, K.; Leighton, T. G.; Ryves, S.; Phillips, D.; Coleman, A. J.

    2011-02-01

    Although extracorporeal shockwave lithotripsy (ESWL) has now been in the clinic for at least three decades, there has been little advance in efforts (i) to estimate the efficacy of the treatment whilst it is in progress, or (ii) to determine the end-point of a treatment session in terms of the degree of stone fragmentation achieved. Previous in vitro experimentation and clinical trials have shown that a passive acoustic monitor has the potential to provide evidence of the effectiveness and end-point of lithotripsy. The system exploits secondary emissions generated during shock-tissue interaction, whose features depend on the quality of tissue at the beam focus. This prototype was developed into the first commercially available clinical ESWL treatment monitor (Precision Acoustic Ltd, Dorchester, UK), and a unit has been acquired and tested in the clinical routine by urologists at Guy's and St Thomas NHS Trust in March 2009. This paper critically assesses the performance of the new system for the first 25 treatments monitored. The ESWL monitor correctly predicted the treatment outcome of 15 of the 18 treatments that were followed-up clinically. In addition, it was noted that the measure of treatment effectiveness provided by the monitor after 500 shocks was predictive of the final treatment outcome (p ESWL or if the patient should be sent for surgery.

  11. A passive acoustic monitor of treatment effectiveness during extracorporeal lithotripsy

    Energy Technology Data Exchange (ETDEWEB)

    Fedele, F; Coleman, A J [Medical Physics Department, Guy' s and St Thomas NHS Foundation Trust, Westminster Bridge Road, SE1 7EH, London (United Kingdom); Thomas, K; Ryves, S; Phillips, D [Urology Department, Guy' s and St Thomas NHS Foundation Trust, Great Maze Pond, SE1 9RT, London (United Kingdom); Leighton, T G, E-mail: fiammetta.fedele@gstt.nhs.uk [Institute of Sound and Vibration Research, University of Southampton, Highfield, S017 1BJ, Southampton (United Kingdom)

    2011-02-01

    Although extracorporeal shockwave lithotripsy (ESWL) has now been in the clinic for at least three decades, there has been little advance in efforts (i) to estimate the efficacy of the treatment whilst it is in progress, or (ii) to determine the end-point of a treatment session in terms of the degree of stone fragmentation achieved. Previous in vitro experimentation and clinical trials have shown that a passive acoustic monitor has the potential to provide evidence of the effectiveness and end-point of lithotripsy. The system exploits secondary emissions generated during shock-tissue interaction, whose features depend on the quality of tissue at the beam focus. This prototype was developed into the first commercially available clinical ESWL treatment monitor (Precision Acoustic Ltd, Dorchester, UK), and a unit has been acquired and tested in the clinical routine by urologists at Guy's and St Thomas NHS Trust in March 2009. This paper critically assesses the performance of the new system for the first 25 treatments monitored. The ESWL monitor correctly predicted the treatment outcome of 15 of the 18 treatments that were followed-up clinically. In addition, it was noted that the measure of treatment effectiveness provided by the monitor after 500 shocks was predictive of the final treatment outcome (p < 0.001). This suggests that the system could be used in pre-assessment; indicating if the stone is susceptible to ESWL or if the patient should be sent for surgery.

  12. Dosimetric Effects Of Different Treatment Tables During Radiotherapy

    International Nuclear Information System (INIS)

    Murkovic, M.; Grego, T.; Bibic, J.

    2015-01-01

    The aim of our study was to measure the effect of mega-voltage photon beam attenuation when treating patients through carbon fibre treatment table with and without the carbon laminate base plate on it. We also examined the ability of XiO treatment planning system in modelling this effect. Direct attenuation measurements were made for two treatment tables, Siemens TxT 550 treatment table with TT-A table top and Elekta Precise table with iBEAM evo table top. On both treatment tables we used Orfit Base Plate (32301). Measurements were taken for two photon energies (6 MV and 18 MV), at two different field sizes (5 x 5 cm 2 and 10 x 10 cm 2 ) and different gantry angles in 50 intervals using stationary water phantom and Farmer type ionization chamber. These values were compared to values calculated in XiO. In order to account for the effect of table and base plate during treatment planning in XiO, customized table and base plate templates were develop in Focal planning system. To construct these customized templates, table and base plate contours as well as respective relative electron density's to water were obtained on CT scanner. The largest attenuation effect was seen for oblique treatment angles using low energy and small field sizes, 6.6 percent for the Elekta table top and 8.4 percent for Siemens table top. In this paper we show that customized table and base plate templates introduced in the patient treatment plan can accurately model the attenuation due to their presence to within 0.3 percent. Since dose modifications due to such carbon fiber accessories can be significant, it can be concluded that introduction of customized table and base plate templates into TPS brings an important improvement to patient treatment planning, and should be included in dose calculations whenever possible. (author).

  13. Telemedicine diabetes consultations are cost-effective, and effects on essential diabetes treatment parameters are similar to conventional treatment

    DEFF Research Database (Denmark)

    Levin, Klaus; Madsen, Jette R; Petersen, Inge

    2013-01-01

    been offered expert diabetes care using teleconsultations. This article describes the impact of the telemedicine solution on essential diabetes treatment parameters, patient satisfaction, and cost-effectiveness. METHODS: Telemedicine consultations were conducted with the patient and nurse specialist...... in transportation time (7 h). Reductions in traveling costs and saved working days were the most important factors in making the telemedicine set-up economically efficient. CONCLUSION: Telemedicine consultation for remote outpatient diabetes control is feasible, and the interdisciplinary interventions achieved high...... treatment quality results in essential diabetes treatment parameters. In addition, the telemedicine set-up was associated with improved cost-effectiveness and patient satisfaction....

  14. In blind pursuit of racial equality?

    Science.gov (United States)

    Apfelbaum, Evan P; Pauker, Kristin; Sommers, Samuel R; Ambady, Nalini

    2010-11-01

    Despite receiving little empirical assessment, the color-blind approach to managing diversity has become a leading institutional strategy for promoting racial equality, across domains and scales of practice. We gauged the utility of color blindness as a means to eliminating future racial inequity--its central objective--by assessing its impact on a sample of elementary-school students. Results demonstrated that students exposed to a color-blind mind-set, as opposed to a value-diversity mind-set, were actually less likely both to detect overt instances of racial discrimination and to describe such events in a manner that would prompt intervention by certified teachers. Institutional messages of color blindness may therefore artificially depress formal reporting of racial injustice. Color-blind messages may thus appear to function effectively on the surface even as they allow explicit forms of bias to persist.

  15. Iterative Estimation in Turbo Equalization Process

    Directory of Open Access Journals (Sweden)

    MORGOS Lucian

    2014-05-01

    Full Text Available This paper presents the iterative estimation in turbo equalization process. Turbo equalization is the process of reception in which equalization and decoding are done together, not as separate processes. For the equalizer to work properly, it must receive before equalization accurate information about the value of the channel impulse response. This estimation of channel impulse response is done by transmission of a training sequence known at reception. Knowing both the transmitted and received sequence, it can be calculated estimated value of the estimated the channel impulse response using one of the well-known estimation algorithms. The estimated value can be also iterative recalculated based on the sequence data available at the output of the channel and estimated sequence data coming from turbo equalizer output, thereby refining the obtained results.

  16. Weighing the potential effectiveness of various treatments for sleep bruxism.

    Science.gov (United States)

    Huynh, Nelly; Manzini, Christiane; Rompré, Pierre H; Lavigne, Gilles J

    2007-10-01

    Sleep bruxism may lead to a variety of problems, but its pathophysiology has not been completely elucidated. As such, there is no definitive treatment, but certain preventive measures and/or drugs may be used in acute cases, particularly those involving pain. This article is intended to guide clinician scientists to the treatment most appropriate for future clinical studies. To determine the best current treatment, 2 measures were used to compare the results of 10 clinical studies on sleep bruxism, 3 involving oral devices and 7 involving pharmacologic therapy. The first measure, the number needed to treat (NNT), allows several randomized clinical studies to be compared and a general conclusion to be drawn. The second measure, effect size, allows evaluation of the impact of treatment relative to a placebo using different studies of similar design. Taking into account the NNT, the effect size and the power of each study, it can be concluded that the following treatments reduce sleep bruxism: mandibular advancement device, clonidine and occlusal splint. However, the first 2 of these have been linked to adverse effects. The occlusal splint is therefore the treatment of choice, as it reduces grinding noise and protects the teeth from premature wear with no reported adverse effects. The NNT could not be calculated for an alternative pharmacologic treatment, short-term clonazepam therapy, which had a large effect size and reduced the average bruxism index. However, the risk of dependency limits its use over long periods. Assessment of efficacy and safety of the most promising treatments will require studies with larger sample sizes over longer periods.

  17. Is desvenlafaxine effective and safe in the treatment of menopausal ...

    African Journals Online (AJOL)

    Meta-analysis was conducted by including double-blind randomized controlled studies on the effectiveness and safety of desvenlafaxine in the treatment of hot flashes. The effectiveness, safety and tolerability of desvenlafaxine were determined by standardized mean differences (SMDs) and Mantel-Haenszel odds ratio.

  18. Comparative study of the effects of treatment techniques on the ...

    African Journals Online (AJOL)

    This paper reports the effects of some fibre treatment techniques namely: mercerization, acetylation and semi-carbonisation on the performance of Kenaf fibres. The treated kenaf fibres which are considered biodegradable, cost effective, renewable and user friendly have been used as a possible base friction material for ...

  19. On the treatment of exchange effects in direct reactions

    International Nuclear Information System (INIS)

    Bencze, G.; Chandler, C.; Argonne National Lab., IL; New Mexico Univ., Albuquerque

    1985-01-01

    Exchange effects in direct reactions are investigated in the framework of the general algebraic theory of identical particle scattering. It is shown that effects due to the permutation symmetry of the system can be separated from the treatment of reaction dynamics. Dynamical aspects of the problem are investigated within the framework of the channel coupling class of N-body theories. (orig.)

  20. Gender Equality and the Corporate Sector

    OpenAIRE

    Lisa Warth

    2009-01-01

    This paper focuses on how the commitment of businesses to promote gender equality within their organisations can be strengthened. A dual approach of encouraging voluntary measures and corporate social responsibility for gender equality on the one hand, and regulating and enforcing change through legislative reforms on the other hand are reviewed, focusing mainly on the European region. There are arguments for a business case for gender equality in terms of better financial performance and com...

  1. Scandinavian Approaches to Gender Equality in Academia

    DEFF Research Database (Denmark)

    Nielsen, Mathias Wullum

    2017-01-01

    This study investigates how Denmark, Norway, and Sweden approach issues of gender equality in research differently. Based on a comparative document analysis of gender equality activities in six Scandinavian universities, together with an examination of the legislative and political frameworks...... surrounding these activities, the article provides new insights into the respective strategies for governing and promoting the advancement of women researchers. In doing so, it exposes some interesting disparities among the cases and shows how Norwegian and Swedish gender equality activities revolve around...

  2. Gender Equality, Citizenship and Human Rights

    DEFF Research Database (Denmark)

    reflect upon challenges to gender equality, citizenship, and human rights in their respective societies; it combines theoretical insights with empirically grounded studies. The volume contextualises feminist political theory in China and the Nordic countries and subsequently puts it into a global......This comparative volume examines the ways in which current controversies and political, legal, and social struggles for gender equality raise conceptual questions and challenge our thinking on political theories of equality, citizenship and human rights. Bringing together scholars and activists who...

  3. Cost effectiveness of treatment for alcohol problems: findings of the randomised UK alcohol treatment trial (UKATT).

    Science.gov (United States)

    2005-09-10

    To compare the cost effectiveness of social behaviour and network therapy, a new treatment for alcohol problems, with that of the proved motivational enhancement therapy. Cost effectiveness analysis alongside a pragmatic randomised trial. Seven treatment sites around Birmingham, Cardiff, and Leeds. 742 clients with alcohol problems; 617 (83.2%) were interviewed at 12 months and full economic data were obtained on 608 (98.5% of 617). Main economic measures Quality adjusted life years (QALYs), costs of trial treatments, and consequences for public sector resources (health care, other alcohol treatment, social services, and criminal justice services). Both therapies saved about five times as much in expenditure on health, social, and criminal justice services as they cost. Neither net savings nor cost effectiveness differed significantly between the therapies, despite the average cost of social behaviour and network therapy (221 pounds sterling; 385 dollars; 320 euros) being significantly more than that of motivational enhancement therapy (129 pounds sterling). If a QALY were worth 30,000 pounds sterling, then the motivational therapy would have 58% chance of being more cost effective than the social therapy, and the social therapy would have 42% chance of being more cost effective than the motivational therapy. Participants reported highly significant reductions in drinking and associated problems and costs. The novel social behaviour and network therapy did not differ significantly in cost effectiveness from the proved motivational enhancement therapy.

  4. Turbo Equalization Using Partial Gaussian Approximation

    DEFF Research Database (Denmark)

    Zhang, Chuanzong; Wang, Zhongyong; Manchón, Carles Navarro

    2016-01-01

    This letter deals with turbo equalization for coded data transmission over intersymbol interference (ISI) channels. We propose a message-passing algorithm that uses the expectation propagation rule to convert messages passed from the demodulator and decoder to the equalizer and computes messages...... returned by the equalizer by using a partial Gaussian approximation (PGA). We exploit the specific structure of the ISI channel model to compute the latter messages from the beliefs obtained using a Kalman smoother/equalizer. Doing so leads to a significant complexity reduction compared to the initial PGA...

  5. Equal rights as the center of democratization

    OpenAIRE

    Alan Gilbert

    2010-01-01

    Well-stated modern political or democratic theory is rights-based. Meaningful democracy rests as a precondition on the equal rights of citizens. This idea stems from Rousseau’s distinction between a general will*one which is impersonal and tends toward equality, that is, the equal basic rights of citizens*and a transitory will of all. For instance, absent equal basic rights, one might imagine a possible world in which what I have called a self-undermining series of wills of all, or the ...

  6. EQUALIZATION OF RESULTS ACCOUNTING POLICIES

    Directory of Open Access Journals (Sweden)

    Florentina MOISESCU

    2014-06-01

    Full Text Available The purpose of this paper is to demonstrate the effect that different accounting policies have on the outcome of an enterprise, this effect being represented either earnings growth or diminishing it. Deprecation policy, the policy related to inventory, policy provisions and related policy borrowing costs are some of the many other possibilities which affect the content of financial statements. Because national and international accounting standards give businesses the flexibility to choose between different policies, managers take advantage of existing loopholes and draw on creative accounting , so that it answers to the needs of the management team.

  7. A quantitative method to evaluate microbial electrolysis cell effectiveness for energy recovery and wastewater treatment

    KAUST Repository

    Ivanov, Ivan

    2013-10-01

    Microbial electrolysis cells (MECs) are potential candidates for sustainable wastewater treatment as they allow for recovery of the energy input by producing valuable chemicals such as hydrogen gas. Evaluating the effectiveness of MEC treatment for different wastewaters requires new approaches to quantify performance, and the establishment of specific procedures and parameters to characterize the outcome of fed-batch treatability tests. It is shown here that Coulombic efficiency can be used to directly calculate energy consumption relative to wastewater treatment in terms of COD removal, and that the average current, not maximum current, is a better metric to evaluate the rate of the bioelectrochemical reactions. The utility of these methods was demonstrated using simulated current profiles and actual wastewater tests. Industrial and domestic wastewaters were evaluated using small volume MECs, and different inoculation strategies. The energy needed for treatment was 2.17kWhkgCOD-1 for industrial wastewater and 2.59kWhkgCOD-1 for domestic wastewater. When these wastewaters were combined in equal amounts, the energy required was reduced to 0.63kWhkgCOD-1. Acclimation of the MEC to domestic wastewater, prior to tests with industrial wastewaters, was the easiest and most direct method to optimize MEC performance for industrial wastewater treatment. A pre-acclimated MEC accomplished the same removal (1847 ± 53 mg L-1) as reactor acclimated to only the industrial wastewater (1839 ± 57 mg L-1), but treatment was achieved in significantly less time (70 h versus 238 h). © 2013, Hydrogen Energy Publications, LLC. Published by Elsevier Ltd. All rights reserved.

  8. [Comparative effectiveness of different treatment methods of liver failure].

    Science.gov (United States)

    Kutepov, D E; Vershinina, M G; Pasechnik, I N; Sal'nikov, P S

    2014-01-01

    It was analyzed the results of treatment of 217 patients (139 men, 78 women) with chronic liver failure in case of liver cirrhosis of various etiology for study of degree of hepatic encephalopathyregression. All patients were divided into 3 groups. In the first group the drug therapy was used. In the second group additionallyplasma exchange was performed, in the third group - alsomolecular absorbent recirculating system was used (effectiveness of MARS-therapy).The results showed that the use of extracorporeal treatment techniques can effectively reduce the severity of hepatic encephalopathy in patients with liver cirrhosis. MARS-therapy improved the neurological status of patientsmore significantly in this case. It is considered that the inclusion of MARS-therapy in the combined treatment of patients leads to a significant reduction of hepatic encephalopathyseverity (1-2 points), in comparison with other methods of treatment.

  9. Cost effective water treatment program in Heavy Water Plant (Manuguru)

    International Nuclear Information System (INIS)

    Mohapatra, C.; Prasada Rao, G.

    2002-01-01

    Water treatment technology is in a state of continuous evolution. The increasing urgency to conserve water and reduce pollution has in recent years produced an enormous demand for new chemical treatment programs and technologies. Heavy water plant (Manuguru) uses water as raw material (about 3000 m 3 /hr) and its treatment and management has benefited the plant in a significant way. It is a fact that if the water treatment is not proper, it can result in deposit formation and corrosion of metals, which can finally leads to production losses. Therefore, before selecting treatment program, complying w.r.t. quality requirements, safety and pollution aspects cost effectiveness shall be examined. The areas where significant benefits are derived, are raw water treatment using polyelectrolyte instead of inorganic coagulant (alum), change over of regenerant of cation exchangers from hydrochloric acid to sulfuric acid and in-house development of cooling water treatment formulation. The advantages and cost effectiveness of these treatments are discussed in detail. Further these treatments has helped the plant in achieving zero discharge and indirectly increased cost reduction of final product (heavy water); the dosage of 3 ppm of polyelectrolyte can replace 90 ppm alum at turbidity level of 300 NTU of raw water which has resulted in cost saving of Rs. 15-20 lakhs in a year beside other advantages; the change over of regenerant from HCl to H 2 SO 4 will result in cost saving of at least Rs.1.4 crore a year besides other advantages; the change over to proprietary formulation to in-house formulation in cooling water treatment has resulted in a saving about Rs.11 lakhs a year. To achieve the above objectives in a sustainable way the performance results are being monitored. (author)

  10. Immunological effects of methylprednisolone pulse treatment in progressive multiple sclerosis

    DEFF Research Database (Denmark)

    Ratzer, R; Romme Christensen, J; Romme Nielsen, B

    2014-01-01

    phenotypes investigated, 25 changed at nominal significance from baseline to week 12 (pmultiple comparisons, we found 5 subpopulations that changed compared to baseline. No pattern were suggesting modulation of Th17 or TFH cells. CONCLUSION: Methylprednisolone pulse treatment has......OBJECTIVE: To investigate the effect of monthly oral methylprednisolone pulse treatment in progressive MS. METHODS: 30 progressive MS patients were treated with oral methylprednisolone every month. Peripheral blood mononuclear cells were analyzed by flow cytometry. RESULTS: Out of 102 leukocyte...

  11. Permutation entropy based time series analysis: Equalities in the input signal can lead to false conclusions

    Energy Technology Data Exchange (ETDEWEB)

    Zunino, Luciano, E-mail: lucianoz@ciop.unlp.edu.ar [Centro de Investigaciones Ópticas (CONICET La Plata – CIC), C.C. 3, 1897 Gonnet (Argentina); Departamento de Ciencias Básicas, Facultad de Ingeniería, Universidad Nacional de La Plata (UNLP), 1900 La Plata (Argentina); Olivares, Felipe, E-mail: olivaresfe@gmail.com [Instituto de Física, Pontificia Universidad Católica de Valparaíso (PUCV), 23-40025 Valparaíso (Chile); Scholkmann, Felix, E-mail: Felix.Scholkmann@gmail.com [Research Office for Complex Physical and Biological Systems (ROCoS), Mutschellenstr. 179, 8038 Zurich (Switzerland); Biomedical Optics Research Laboratory, Department of Neonatology, University Hospital Zurich, University of Zurich, 8091 Zurich (Switzerland); Rosso, Osvaldo A., E-mail: oarosso@gmail.com [Instituto de Física, Universidade Federal de Alagoas (UFAL), BR 104 Norte km 97, 57072-970, Maceió, Alagoas (Brazil); Instituto Tecnológico de Buenos Aires (ITBA) and CONICET, C1106ACD, Av. Eduardo Madero 399, Ciudad Autónoma de Buenos Aires (Argentina); Complex Systems Group, Facultad de Ingeniería y Ciencias Aplicadas, Universidad de los Andes, Av. Mons. Álvaro del Portillo 12.455, Las Condes, Santiago (Chile)

    2017-06-15

    A symbolic encoding scheme, based on the ordinal relation between the amplitude of neighboring values of a given data sequence, should be implemented before estimating the permutation entropy. Consequently, equalities in the analyzed signal, i.e. repeated equal values, deserve special attention and treatment. In this work, we carefully study the effect that the presence of equalities has on permutation entropy estimated values when these ties are symbolized, as it is commonly done, according to their order of appearance. On the one hand, the analysis of computer-generated time series is initially developed to understand the incidence of repeated values on permutation entropy estimations in controlled scenarios. The presence of temporal correlations is erroneously concluded when true pseudorandom time series with low amplitude resolutions are considered. On the other hand, the analysis of real-world data is included to illustrate how the presence of a significant number of equal values can give rise to false conclusions regarding the underlying temporal structures in practical contexts. - Highlights: • Impact of repeated values in a signal when estimating permutation entropy is studied. • Numerical and experimental tests are included for characterizing this limitation. • Non-negligible temporal correlations can be spuriously concluded by repeated values. • Data digitized with low amplitude resolutions could be especially affected. • Analysis with shuffled realizations can help to overcome this limitation.

  12. Effect of magnetic resonance imaging characteristics on uterine fibroid treatment

    Directory of Open Access Journals (Sweden)

    Duc NM

    2018-04-01

    Full Text Available Nguyen Minh Duc, Huynh Quang HuyDepartment of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, VietnamAbstract: Uterine fibroids are the most common gynecological benign tumors adversely affecting the quality of life of women of a reproductive age. Magnetic resonance imaging (MRI is efficient at localizing the site of lesions and characterizing uterine fibroids before treatment. Understanding the different characteristics of uterine fibroids on MRI is essential, because it not only enables prompt diagnosis, but also guides the development of suitable therapeutic methods. This pictorial review demonstrates the effect of MRI features on uterine fibroid treatment. Keywords: uterine fibroids, characteristics, magnetic resonance imaging, treatments

  13. Cost-effectiveness analysis of treatments for premenstrual dysphoric disorder.

    Science.gov (United States)

    Rendas-Baum, Regina; Yang, Min; Gricar, Joseph; Wallenstein, Gene V

    2010-01-01

    Premenstrual syndrome (PMS) is reported to affect between 13% and 31% of women. Between 3% and 8% of women are reported to meet criteria for the more severe form of PMS, premenstrual dysphoric disorder (PMDD). Although PMDD has received increased attention in recent years, the cost effectiveness of treatments for PMDD remains unknown. To evaluate the cost effectiveness of the four medications with a US FDA-approved indication for PMDD: fluoxetine, sertraline, paroxetine and drospirenone plus ethinyl estradiol (DRSP/EE). A decision-analytic model was used to evaluate both direct costs (medication and physician visits) and clinical outcomes (treatment success, failure and discontinuation). Medication costs were based on average wholesale prices of branded products; physician visit costs were obtained from a claims database study of PMDD patients and the Agency for Healthcare Research and Quality. Clinical outcome probabilities were derived from published clinical trials in PMDD. The incremental cost-effectiveness ratio (ICER) was calculated using the difference in costs and percentage of successfully treated patients at 6 months. Deterministic and probabilistic sensitivity analyses were used to assess the impact of uncertainty in parameter estimates. Threshold values where a change in the cost-effective strategy occurred were identified using a net benefit framework. Starting therapy with DRSP/EE dominated both sertraline and paroxetine, but not fluoxetine. The estimated ICER of initiating treatment with fluoxetine relative to DRSP/EE was $US4385 per treatment success (year 2007 values). Cost-effectiveness acceptability curves revealed that for ceiling ratios>or=$US3450 per treatment success, fluoxetine had the highest probability (>or=0.37) of being the most cost-effective treatment, relative to the other options. The cost-effectiveness acceptability frontier further indicated that DRSP/EE remained the option with the highest expected net monetary benefit for

  14. Neuroprotective effects of testosterone treatment in men with multiple sclerosis

    Directory of Open Access Journals (Sweden)

    Florian Kurth

    2014-01-01

    Full Text Available Multiple sclerosis (MS is an inflammatory and neurodegenerative disease of the central nervous system. While current medication reduces relapses and inflammatory activity, it has only a modest effect on long-term disability and gray matter atrophy. Here, we have characterized the potential neuroprotective effects of testosterone on cerebral gray matter in a pilot clinical trial. Ten men with relapsing–remitting MS were included in this open-label phase II trial. Subjects were observed without treatment for 6 months, followed by testosterone treatment for another 12 months. Focal gray matter loss as a marker for neurodegeneration was assessed using voxel-based morphometry. During the non-treatment phase, significant voxel-wise gray matter decreases were widespread (p≤ 0.05 corrected. However, during testosterone treatment, gray matter loss was no longer evident. In fact, a significant gray matter increase in the right frontal cortex was observed (p≤ 0.05 corrected. These observations support the potential of testosterone treatment to stall (and perhaps even reverse neurodegeneration associated with MS. Furthermore, they warrant the investigation of testosterone's neuroprotective effects in larger, placebo controlled MS trials as well as in other neurodegenerative diseases. This is the first report of gray matter increase as the result of treatment in MS.

  15. Not all Anchors Weigh Equally.

    Science.gov (United States)

    Greenstein, Michael; Velazquez, Alexandra

    2017-11-01

    The anchoring bias is a reliable effect wherein a person's judgments are affected by initially presented information, but it is unknown specifically why this effect occurs. Research examining this bias suggests that elements of both numeric and semantic priming may be involved. To examine this, the present research used a phenomenon wherein people treat numeric information presented differently in Arabic numeral or verbal formats. We presented participants with one of many forms of an anchor that represented the same value (e.g., twelve hundred or 1,200). Thus, we could examine how a concept's meaning and its absolute numeric value affect anchoring. Experiments 1 and 2 showed that people respond to Arabic and verbal anchors differently. Experiment 3 showed that these differences occurred largely because people tend to think of numbers in digit format. This suggests that one's conceptual understanding of the anchored information matters more than its strict numeric value.

  16. Comparação da eficácia de doses iguais de acetaminofeno retal e oral em crianças Comparison of antipyretic effectiveness of equal doses of rectal and oral acetaminophen in children

    Directory of Open Access Journals (Sweden)

    Sedigha Akhavan Karbasi

    2010-06-01

    Full Text Available OBJETIVO: Comparar uma dose de acetaminofeno oral e retal e avaliar a aceitabilidade do acetaminofeno retal, uma vez que o acetaminofeno oral e retal é amplamente usado como agente antipirético em crianças com febre e a eficiência comparativa dessas duas preparações não está bem estabelecida. MÉTODOS: Neste estudo prospectivo de grupos paralelos, foram incluídas 60 crianças admitidas na emergência ou clínica ambulatorial pediátrica em um hospital terciário, com idade entre 6 meses e 6 anos e com temperatura retal acima de 39 °C. Os pacientes foram distribuídos aleatoriamente em dois grupos de mesmo tamanho. O grupo 1 recebeu 15 mg/kg de acetaminofeno retal, e o grupo 2 recebeu a mesma dose oralmente. A temperatura foi registrada no tempo zero e 1 e 3 horas após administração da droga. RESULTADOS: No primeiro grupo, a redução média de temperatura, 1 e 3 horas após administração do acetaminofeno, foi de 1,07±0,16 (p 0,05. CONCLUSÃO: As preparações oral e retal de acetaminofeno têm eficácia antipirética equivalente em crianças. A via retal mostrou ser tão aceitável quanto a oral entre os pais.OBJECTIVE: To compare a dose of oral and rectal acetaminophen and to evaluate acceptability of rectal acetaminophen, since oral and rectal acetaminophen is widely used as an antipyretic agent in febrile children and the comparative effectiveness of these two preparations is not well established. METHODS: In this prospective parallel group designed study, 60 children who presented to the emergency department or outpatient pediatric clinic at a tertiary hospital and aged from 6 months to 6 years with rectal temperature over 39 °C were enrolled. Patients were randomly assigned to two equal-sized groups. Group 1 received 15 mg/kg acetaminophen rectally and group 2 received the same dose orally. Temperature was recorded at baseline and 1 and 3 hours after drug administration. RESULTS: In the first group, mean decrease in

  17. Waking self-hypnosis efficacy in cognitive-behavioral treatment for pathological gambling: an effectiveness clinical assay.

    Science.gov (United States)

    Lloret, Daniel; Montesinos, Rosa; Capafons, Antonio

    2014-01-01

    Cognitive-behavioral therapy for pathological gambling has a long-term success rate of more than 50%. This study evaluated the effect of self-hypnosis in cognitive-behavioral treatment of pathological gamblers. Forty-nine participants were assigned to 2 groups. Both groups received a cognitive-behavioral protocol, and Group 1, the no-hypnosis group, received an 11-session intervention and Group 2, the hypnosis group, received 7 sessions that included self-hypnosis. Both groups were equal in gambling chronicity, frequency, intensity, change motivation, and problems derived from gambling. All participants reported significant improvement in gambling behavior and consequences at both treatment end and 6-month follow-up. Data show no differences between the interventions in abstinence, therapeutic compliance, fulfillment, and satisfaction. Results suggest that self-hypnosis reinforces treatment and can be a supportive technique for future brief interventions.

  18. Late effects of treatment of cancer in infancy

    International Nuclear Information System (INIS)

    Pastore, G.; Antonelli, R.; Fine, W.; Li, F.P.; Sallan, S.E.

    1982-01-01

    Eighty-six children were diagnosed with cancer in infancy, followed for at lest 5 years, and assessed for late effects of disease and therapy. One child subsequently died from respiratory failure and 3 died from second primary cancers. Another patient survived second primary cancers of the skin. The high frequency of new cancers (4 observed, 0.09 expected) was attributable to host susceptibility factors and treatment effects. Kyphoscoliosis was diagnosed in 44 patients, 40 of whom had received radiotherapy to the spine. Other patients had neurologic deficits, pulmonary fibrosis, hypoplastic breasts, bowel adhesions, thyroid nodules, musculoskeletal defects, and liver fibrosis associated with tumor therapy. Sequelae of cancer were more common after treatment in infancy than in later childhood. Improved treatments and knowledge of natural history can reduce adverse effects of therapy

  19. Effects of unplanned treatment interruptions on HIV treatment failure– results from TAHOD

    Science.gov (United States)

    Jiamsakul, Awachana; Kerr, Stephen J.; Ng, Oon Tek; Lee, Man Po; Chaiwarith, Romanee; Yunihastuti, Evy; Van Nguyen, Kinh; Pham, Thuy Thanh; Kiertiburanakul, Sasisopin; Ditangco, Rossana; Saphonn, Vonthanak; Sim, Benedict L. H.; Merati, Tuti Parwati; Wong, Wingwai; Kantipong, Pacharee; Zhang, Fujie; Choi, Jun Yong; Pujari, Sanjay; Kamarulzaman, Adeeba; Oka, Shinichi; Mustafa, Mahiran; Ratanasuwan, Winai; Petersen, Boondarika; Law, Matthew; Kumarasamy, Nagalingeswaran

    2016-01-01

    Objectives Treatment interruptions (TI) of combination antiretroviral therapy (cART) are known to lead to unfavourable treatment outcomes but do still occur in resource-limited settings. We investigated the effects of TI associated with adverse events (AEs) and non-AE-related reasons, including their durations, on treatment failure after cART resumption in HIV-infected individuals in Asia. Methods Patients initiating cART between 2006-2013 were included. TI was defined as stopping cART for >1 day. Treatment failure was defined as confirmed virological, immunological or clinical failure. Time to treatment failure during cART was analysed using Cox regression, not including periods off treatment. Co-variables with p30 days were associated with failure (31-180 days HR=2.66, 95%CI (1.70-4.16); 181-365 days HR=6.22, 95%CI (3.26-11.86); and >365 days HR=9.10, 95% CI (4.27-19.38), all pfailure. If TI is unavoidable, its duration should be minimised to reduce the risk of failure after treatment resumption. PMID:26950901

  20. Cost-effectiveness analysis of optimal strategy for tumor treatment

    International Nuclear Information System (INIS)

    Pang, Liuyong; Zhao, Zhong; Song, Xinyu

    2016-01-01

    We propose and analyze an antitumor model with combined immunotherapy and chemotherapy. Firstly, we explore the treatment effects of single immunotherapy and single chemotherapy, respectively. Results indicate that neither immunotherapy nor chemotherapy alone are adequate to cure a tumor. Hence, we apply optimal theory to investigate how the combination of immunotherapy and chemotherapy should be implemented, for a certain time period, in order to reduce the number of tumor cells, while minimizing the implementation cost of the treatment strategy. Secondly, we establish the existence of the optimality system and use Pontryagin’s Maximum Principle to characterize the optimal levels of the two treatment measures. Furthermore, we calculate the incremental cost-effectiveness ratios to analyze the cost-effectiveness of all possible combinations of the two treatment measures. Finally, numerical results show that the combination of immunotherapy and chemotherapy is the most cost-effective strategy for tumor treatment, and able to eliminate the entire tumor with size 4.470 × 10"8 in a year.

  1. The treatment of late radiation effects with hyperbaric oxygenation (HBO)

    International Nuclear Information System (INIS)

    Plafki, C.; Carl, U.M.; Glag, M.; Hartmann, K.A.

    1998-01-01

    Background: Late radiation injuries may impose a negative influence on the quality of life in the affected patients. In several entities, standardized treatment protocols are lacking. Hyperbaric oxygenation (HBO) has been shown to have beneficial effects in the treatment of late radiation sequelae. Material and methods: The basic principles of HBO are reviewed as well as clinical issues. Current study protocols are presented. Results: During HBO-therapy the patient breathes pure oxygen at pressures above 100 kPa. The oxygen solubility within the fluid phase of the blood is largely increased. Biological effects include an increased oxygen diffusibility, improved collagen synthesis and neoangiogenesis as well as an enhancement of antimicrobial defenses. By decreasing the capillary filtration pressure a reduction of edema becomes possible. HBO has been shown to prevent complications following surgery in irradiated tissues. Its efficacy as an adjunct in the treatment of osteonecroses in radiation patients could be demonstrated. In addition, the loss of osseointegrated implants in the maxillofacial bones of these patients could be significantly reduced. Further indications include soft tissue necroses, hemorrhagic cystitis and proctitis in tumor patients that have been treated by radiotherapy as part of a multimodality approach. Conclusions: HBO in the treatment of late radiation effects is still subject of investigation, but remarkable results have been reported. Optimized treatment protocols need to be determined in various entities. The rate of side effects is acceptable low. (orig.) [de

  2. Domestic Equality and Marital Stability

    DEFF Research Database (Denmark)

    Steingrimsdottir, Herdis; Vardardottir, Arna

    by the father while parents who had a child before were did not get this option. This created large economic incentives for parents to involve fathers in caring for their children during their first months. In this paper we use the precise timing of the introduction of the paternal quota in Iceland to evaluate...... the causal effects of paternity leave on parents’ earnings, the gender wage gap and marital stability. The results are obtained using detailed register based panel data, comparing families who had a child just before or just after the reform. Spouses who are entitled to paternity leave are less likely...

  3. Cost-effective treatment for the couple with infertility.

    Science.gov (United States)

    Van Voorhis, B J; Syrop, C H

    2000-12-01

    Although the evaluation of cost-effective approaches to infertility treatment remains in its infancy, several important principles have emerged from the initial studies in this field. Currently, in treating couples with infertility without tubal disease or severe male-factor infertility, the most cost-effective approach is to start with IUI or superovulation-IUI treatments before resorting to IVF procedures. The woman's age and number of sperm present for insemination are significant factors influencing cost-effectiveness. The influence of certain diagnoses on the cost-effectiveness of infertility treatments requires further study. Even when accounting for the costs associated with multiple gestations and premature deliveries, the cost of IVF decreases within the range of other cost-effective medical procedures and decreases to less than the willingness to pay for these procedures. Indeed, for patients with severe tubal disease, IVF has been found to be more cost-effective than surgical repair. The cost-effectiveness of IVF will likely improve as success rates show continued improvements over the course of time. In addition, usefulness of embryo selection and practices to reduce the likelihood of high-order multiple pregnancies, without reductions in pregnancy rates, will significantly impact cost-effectiveness. The exclusion of infertility treatments from insurance plans is unfortunate and accentuates the importance of physicians understanding the economics of infertility treatment with costs that are often passed directly to the patient. The erroneous economic policies and judgments that have led to inequities in access to infertility health care should not be tolerated.

  4. Central nervous system side effects associated with zolpidem treatment.

    Science.gov (United States)

    Toner, L C; Tsambiras, B M; Catalano, G; Catalano, M C; Cooper, D S

    2000-01-01

    Zolpidem is one of the newer medications developed for the treatment of insomnia. It is an imidazopyridine agent that is an alternative to the typical sedative-hypnotic agents. Zolpidem use is gaining favor because of its efficacy and its side effect profile, which is milder and less problematic than that of the benzodiazepines and barbiturates used to treat insomnia. Still, side effects are not uncommon with zolpidem use. We report a series of cases in which the patients developed delirium, nightmares and hallucinations during treatment with zolpidem. We will review its pharmacology, discuss previous reports of central nervous system side effects, examine the impact of drug interactions with concurrent use of antidepressants, examine gender differences in susceptibility to side effects, and explore the significance of protein binding in producing side effects.

  5. Diversity, equal opportunities and human rights.

    Science.gov (United States)

    McKimm, Judy; Webb, Helen

    2010-08-01

    Equality and diversity are central to education and health services, in terms of both employment and service delivery. Clinical teachers need to be able to support students and trainees around equality issues, have the confidence to challenge discriminatory practice and provide an inclusive and safe learning and teaching environment.

  6. The Many Faces of Equal Opportunity

    Science.gov (United States)

    Temkin, Larry S.

    2016-01-01

    The ideal of equality of opportunity plays an important role in contemporary social and political discourse, and it is one of the few ideals which most people, across the political spectrum, accept. In this article, I argue that the seemingly widespread agreement about the value of equal opportunity is more apparent than real. I distinguish…

  7. Some equalities and inequalities for fusion frames

    OpenAIRE

    Guo, Qianping; Leng, Jinsong; Li, Houbiao

    2016-01-01

    Fusion frames have some properties similar to those of frames in Hilbert spaces, but not all of their properties are similar. Some authors have established some equalities and inequalities for conventional frames. In this paper, we give some equalities and inequalities for fusion frames. Our results generalize and improve the remarkable results which have been obtained by Balan, Casazza and G?vruta etc.

  8. Detroit's Fight for Equal Educational Opportunity.

    Science.gov (United States)

    Zwerdling, A. L.

    To meet the challenge of equal educational opportunity, current methods of public school finance must be revised. The present financial system, based on State equalization of local property tax valuation, is inequitable since it results in many school districts, particularly those in large cities, having inadequate resources to meet extraordinary…

  9. Vocational Education and Equality of Opportunity.

    Science.gov (United States)

    Horowitz, Benjamin; Feinberg, Walter

    1990-01-01

    Examines the concepts of equality of opportunity and equality of educational opportunity and their relationship to vocational education. Traces the history of vocational education. Delineates the distinction between training and education as enumerated in Aristotelian philosophy. Discusses the role vocational education can play in the educative…

  10. 78 FR 53231 - Women's Equality Day, 2013

    Science.gov (United States)

    2013-08-28

    ... Vol. 78 Wednesday, No. 167 August 28, 2013 Part IV The President Proclamation 9003--Women's Equality Day, 2013 Proclamation 9004--50th Anniversary of the March on Washington for Jobs and Freedom #0... 9003 of August 23, 2013 Women's Equality Day, 2013 By the President of the United States of America A...

  11. 34 CFR 108.6 - Equal access.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Equal access. 108.6 Section 108.6 Education Regulations of the Offices of the Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION EQUAL... limited to, school-related means of communication, such as bulletin board notices and literature...

  12. On heterogeneity of treatment effects and clinical freedom.

    Science.gov (United States)

    Sacristán, J A; Avendaño-Solá, C

    2015-01-01

    Three decades ago, John R Hampton announced the death of clinical freedom. Since then, evidence-based medicine has been the predominant paradigm in clinical research. By applying a population-based approach, the randomised controlled trial has become the cornerstone for demonstrating the overall effect of a treatment and for developing guidelines. The new patient-centred medicine movement is rediscovering the important implications of heterogeneity of treatment effects for clinical practice and that a better understanding of such variability can contribute to improve health outcomes for individual patients through practicing a science-based clinical freedom. © 2015 The Authors. International Journal of Clinical Practice Published by John Wiley & Sons Ltd.

  13. Cost effective treatment for wet FGD scrubber bleedoff

    Energy Technology Data Exchange (ETDEWEB)

    Janecek, K.F. [EIMCO Process Equipment Company, Salt Lake City, UT (United States); Kim, J.Y. [Samkook Corporation, Seoul (Korea, Democratic People`s Republic of)

    1994-12-31

    The dewatering of scrubber bleedoff gypsum is a thoroughly proven technology, whether for production of wallboard grade gypsum or environmentally responsible land fill. Careful review of the technology options will show which one is the most effective for the specific plant site. Likewise, a recipe for wastewater treatment for heavy metals removal can be found that will meet local regulatory limits. EIMCO has worldwide experience in FGD gypsum sludge dewatering and wastewater treatment. Contacting EIMCO can be the most important step toward a practical cost effective system for handling FGD scrubber bleed slurries.

  14. Late effects of treatment of cancer in children

    International Nuclear Information System (INIS)

    Byrd, R.L.

    1983-01-01

    Advances in surgical techniques, in chemotherapy, and in radiation therapy have led to improved survival in children treated for cancer. Children cured of cancer will soon form a significant fraction of our adult population. As we follow such survivors, we have become more aware of long-term side effects of treatment. This is not a reason to withhold therapy. Instead, careful followup of oncology patients is needed to document the late effects, to identify the etiologic agents, and to alter treatment to give the least toxic therapy without sacrificing quality or duration of survival

  15. Justifications of Gender Equality in Academia

    DEFF Research Database (Denmark)

    Nielsen, Mathias Wullum

    2014-01-01

    and Swedish universities juxtapose arguments of utility, innovation, justice, and anti-discrimination, the Danish universities primarily refer to aspects of competitiveness, utility, and innovation when justifying activities on gender equality. The article suggests that the lack of justice......Gender equality in academia is often perceived as receiving more emphasis in Norway and Sweden than in Denmark. But how do the public research institutions in the three countries approach issues of gender equality differently? This study investigates how activities related to gender equality...... are articulated and justified in the policy statements of six Scandinavian universities. The analysis reveals some interesting disparities between the countries. In short, the Danish universities seem to be reluctant to deal with gender equality on the basis of rights-based assumptions. While the Norwegian...

  16. Effect of Surface Treatment on the Properties of Wool Fabric

    Science.gov (United States)

    Kan, C. W.; Yuen, C. W. M.; Chan, C. K.; Lau, M. P.

    Wool fiber is commonly used in textile industry, however, it has some technical problems which affect the quality and performance of the finished products such as felting shrinkage, handle, lustre, pilling, and dyeability. These problems may be attributed mainly in the presence of wool scales on the fiber surface. Recently, chemical treatments such as oxidation and reduction are the commonly used descaling methods in the industry. However, as a result of the pollution caused by various chemical treatments, physical treatment such as low temperature plasma (LTP) treatment has been introduced recently because it is similarly capable of achieving a comparable descaling effect. Most of the discussions on the applications of LTP treatment on wool fiber were focused on applying this technique for improving the surface wettability and shrink resistance. Meanwhile, little discussion has been made on the mechanical properties, thermal properties, and the air permeability. In this paper, wool fabric was treated with LTP treatment with the use of a non-polymerizing gas, namely oxygen. After the LTP treatment, the fabrics low-stress mechanical properties, air permeability, and thermal properties were evaluated and discussed.

  17. [Cost effectiveness in treatment of acute myeloid leukemia].

    Science.gov (United States)

    Nordmann, P; Schaffner, A; Dazzi, H

    2000-12-23

    Although the rise in health costs is a widely debated issue, in Switzerland it was until recently taken for granted that patients are given the best available treatment regardless of cost. An example of a disease requiring costly treatment is acute myelogenous leukaemia (AML). To relate cost to benefit we calculated expenditure per life years gained. To assess costs we determined the real cost of treatment up to total remission, followed by consolidation or withdrawal of treatment or death. For survival time exceeding the 2-year observation period we used data from recent literature. The average cost of treatment ranges up to 107,592 Swiss francs (CHF). In 1997 we treated 23 leukaemia patients at Zurich University Hospital and gained a total of 210 life years. This represents an average cost of CHF 11,741 per life year gained. Chief cost items were therapy and personnel costs for nursing staff, followed by hotel business and personnel costs for doctors and diagnosis. Our results for AML treatment are far removed from the $61,500 ranging up to $166,000 discussed in the literature as the "critical" QALY (quality adjusted life years) value. This is the first time the actual costs of AML therapy have been shown for a Swiss cohort. Despite high initial treatment costs and success only in a limited number of patients, the expenditure per QALY is surprisingly low and shows clearly the effectiveness of apparently costly acute medicine.

  18. The effects of surface treatments on rapid chloride permeability tests

    KAUST Repository

    Yoon, Seyoon

    2012-08-01

    Surface treatments are commonly applied to improve the chloride resistance of concrete structures exposed to saline environments. Information on chloride ingress to surface-treated concrete is mostly provided by application of the rapid chloride permeability test (RCPT); this test is short in duration and provides rapid results. This study presents a numerical formulation, based on the extended Nernst-Plank/Poisson (NPP) equation, to model the effect of the surface treatment on a sample tested by RCPT. Predictions of the model are compared to experimental measurements. The simulations show that the results from RCPT, in terms of ionic profiles and measurement of the electric field, are dependent on the effectiveness of surface treatments. During RCPT, highly effective surface treatments cause both cations and anions to flocculate at the interface between the surface treatment and the concrete, creating a local electric field. Our numerical model includes these phenomena and presents a methodology to obtain more accurate diffusivities of the surface-treated- concrete from RCPT. © 2012 Elsevier B.V. All rights reserved.

  19. The effects of surface treatments on rapid chloride permeability tests

    KAUST Repository

    Yoon, Seyoon; Oh, Sang-gyun; Ha, Juyoung; Monteiro, Paulo M.

    2012-01-01

    Surface treatments are commonly applied to improve the chloride resistance of concrete structures exposed to saline environments. Information on chloride ingress to surface-treated concrete is mostly provided by application of the rapid chloride permeability test (RCPT); this test is short in duration and provides rapid results. This study presents a numerical formulation, based on the extended Nernst-Plank/Poisson (NPP) equation, to model the effect of the surface treatment on a sample tested by RCPT. Predictions of the model are compared to experimental measurements. The simulations show that the results from RCPT, in terms of ionic profiles and measurement of the electric field, are dependent on the effectiveness of surface treatments. During RCPT, highly effective surface treatments cause both cations and anions to flocculate at the interface between the surface treatment and the concrete, creating a local electric field. Our numerical model includes these phenomena and presents a methodology to obtain more accurate diffusivities of the surface-treated- concrete from RCPT. © 2012 Elsevier B.V. All rights reserved.

  20. Effectiveness of medication / auricular therapy / phyto-therapy combination in the treatment of hypertensive patients

    Directory of Open Access Journals (Sweden)

    José Ramón Martínez Pérez

    2015-10-01

    Full Text Available Background: hypertension is one of the main cardiovascular risk factors, so its control improves the life expectancy of patients.Objective: to assess the effects of a treatment combining medication with auricular therapy and phyto-therapy in hypertensive patients assisted at the health area of ”Romárico Oro” Polyclinic, in Puerto Padre, Las Tunas province.Methods: an intervention study was carried out in 68 hypertensive patients of the health area of “Romárico Oro” Polyclinic in Puerto Padre from April, 2013 to April, 2014. The patients were distributed at random into two equal groups; the first received medication combined with auricular therapy and phyto-therapy, while the second one received only medication. The statistical analysis was done by means of Statistic system, t-student and Chi-Square tests were used and p< or =0.05 was considered as level of statistical significance.Results: by the end of the intervention, 73, 53% of the patients of the group with the combination of drug treatment and auricular therapy and phyto-therapy were controlled. In this group, the diastolic filling pressure diminished to 2, 2 mm Hg and the systolic gradient to 3, 66 mm, regarding the group treated only with drugs. Only one patient, representing the 2, 94% showed adverse reaction to the natural and traditional treatment.Conclusions: the combination of medication with auricular therapy and phyto-therapy proved to be effective, corroborated by a significant decrease of quantity of crisis, diastolic and systolic filling pressure values and increase of number of patients with their disease controlled; the report of only one complication shows the innocuousness of the auricular therapy and phyto-therapy treatment.

  1. An equal opportunity power market

    International Nuclear Information System (INIS)

    Williams, P.L.

    1992-01-01

    As the House and Senate head to conference on the energy bill, the outlook for PUHCA reform and mandatory wholesale transmission access is excellent. During the opening months of 1991, the US Senate was debating the administration's proposal for a comprehensive national energy strategy. Reform of the Public Utilities Holding Company Act of 1935 (PUHCA) was a controversial issue in that debate. Independent energy producers and others strongly supported reform but investor-owned utilities were sharply split on the issue. The Senate refused to consider transmission access, and it was the one issue which had the potential to unite the investor-owned utility community in opposition to PUHCA reform. Now, as we approach the mid-point of 1992, the Senate and the House have passed energy bills and are headed to conference to work out their differences. There is no longer effective opposition to PUHCA reform, and although the Senate would still prefer to avoid the issue, transmission access appears likely to be included in the final energy package. Energy legislation will almost certainly be enacted before the November elections and was expected possibly as early as June. This article addresses transmission access, transmission policies, voluntary transmission, independent power producers influence, the retail wheeling juggernaut, and Public Utilities Holding Company Act reform

  2. The effect of parental presence on the child's perception and co-operation during dental treatment

    NARCIS (Netherlands)

    Boka, V.; Arapostathis, K.; Karagiannis, V.; Kotsanos, N.; van Loveren, C.; Veerkamp, J.

    2016-01-01

    Aim This was to study the influence of parental presence during dental treatment on children’s behaviour and perception. Methods Parents of 100 patients (mean age 7 ± 2.2 years) who visited the Postgraduate Paediatric Dental Clinic were randomly divided into two equal groups during one

  3. Somato-Visceral Effects in the Treatment of Dysmenorrhea: Neuromuscular Manual Therapy and Standard Pharmacological Treatment.

    Science.gov (United States)

    Barassi, Giovanni; Bellomo, Rosa Grazia; Porreca, Annamaria; Di Felice, Piera Attilia; Prosperi, Loris; Saggini, Raoul

    2018-03-01

    This study aims to verify whether neuromuscular therapy (NMT) or pharmacology therapy (PT) is more effective for reducing symptoms in women affected by primary dysmenorrhea and the effects associated with each treatment. A controlled, randomized, single-blind clinical trial within the framework of the chair of physical medicine and rehabilitation of the University "G. d'Annunzio" of Chieti-Pescara. The study was conducted on a sample of 60 women suffering from primary dysmenorrhea. Subjects were randomly divided in two groups (A and B). Group A was treated with NMT and group B with PT. Group B was given ibuprofen or naproxen because they are considered the best painkillers for this condition. Group A was treated with 8 neuromuscular manual lumbosacral and abdominal therapy sessions twice per week for 4 weeks. Results were analyzed at the beginning (T0) and end (T1) of the study with a menstrual distress questionnaire, brief pain inventory, and visual analogue scale. Twenty patients from Group A were selected for evaluation of their maintenance of the eventual improvement that was detected in T1 at follow-up (T2). Both therapies had significant short-term effects in reducing the perception and duration of pain. However, NMT appears to give more improvements in the duration of pain. NMT had a long-term effect on perception of pain because patients conserved the positive effects of treatment after 4 weeks. NMT also had a long-term effect on duration of pain because patients conserved benefits of treatment, but this improvement started to decrease after 4 weeks. In the treatment of primary dysmenorrhea, NMT represents a valid therapeutic alternative method to PT. NMT is free from potential adverse effects of analgesics, is noninvasive, and is easy to perform.

  4. Effectiveness of improved treatment of inflamatory bowel disiseases in infants

    Directory of Open Access Journals (Sweden)

    Marushko RV

    2015-01-01

    Full Text Available Actually is required to improve the treatment of chronic inflammatory bowel disease in infants on the principles of safety of therapeutic interventions and the impact on the basic pathogenetic mechanisms involved in the formation of the pathology of the bowel. Purpose — to evaluate the effectiveness of improved treatment of chronic non"specific non"ulcered colitis in infants using functional foods (pro", prebiotics, omega-3 long chain polyunsaturated fatty acids, L-carnitine, hepatoprotectors and alternative formulas. Patients and methods. A total of 114 infants (from 9 months up to 3 years of life with chronic non-specific non-ulcerated (unidentified colitis were studded. Researched the effectiveness of improved treatment using pro-, prebiotics, omega-3 long chain polyunsaturated fatty acids, L-carnitine, hepatoprotectors and semi-elemental formula of chronic non-specific non-ulcerated colitis on the basis of clinical and laboratory research methods, including bacteriological and immunological (TNF-α, ITF in serum, SIgA in coprofiltrates. Were used chronic non-specific non-ulcerated colitis activity index and the index of endoscopic changes of the intestinal mucosa during the treatment in infants. Results. It is shown that the use of functional foods as multiprobiotics, prebiotics, omega-3 polyunsaturated fatty acids and enhancing cellular energy provitamins as well as hepatoprotectors and alternative formulas in the treatment of chronic colitis in infants contributes to a significant improvement in the results of chronic non-specific non-ulcerated colitis treatment, more rapidly elimination of main symptoms and increase the number of positive results of treatment in infants with chronic non-specific non-ulcerated colitis (80.4% versus 55.2%. Conclusions. Results of the study allow us to recommend the use of elaborated improved treatment in infants with chronic non-specific non-ulcerated colitis on different levels of child healthcare.

  5. On the treatment of exchange effects in direct reactions

    International Nuclear Information System (INIS)

    Bencze, Gy.

    1984-11-01

    In the theoretical description of direct nuclear reactions the dynamic effects are combined with 'kinematical' effects due to the quantum mechanical exchange interaction caused by the Pauli principle governing the mechanics of identical particles. In the present paper it is shown that in the frame of general algebraic theory of identical particle scattering the effects of the permutational symmetry of nucleons can be separated on an exact way from the treatment of reaction dynamics. Dynamical approximations may be used only after the separation of permutational effects. (D.Gy.)

  6. Effects of surface treatments on microstructure in stainless steel

    International Nuclear Information System (INIS)

    Mabuchi, Yasuhiro; Tamako, Hiroaki; Kaneda, Junya; Yamashita, Norimichi; Miyakawa, Masahiko

    2009-01-01

    It is revealed that Stress Corrosion Cracking (SCC) on the surface of the L-grade stainless steels in Nuclear Power Plants is caused by heavily cold work of the materials. The microstructure, hardness and residual stress on the surface of the material are factors for SCC initiation. There are surface treatment methods that is effective reduction on SCC such as Flap Wheel (FW) polishing, Clean N Strip (CNS) polishing, Water Jet Peening (WJP) and Shot Peening (SP). In this paper, the characteristics of the surface cold worked layer of the L-grade stainless steels conducted by above-mentioned surface treatments are analyzed, and effects of the surface treatments on the surface layer are discussed. (author)

  7. [Undesired treatment effects in behavior group therapy: Frequency and spectrum].

    Science.gov (United States)

    Linden, M; Walter, M; Fritz, K; Muschalla, B

    2015-11-01

    Psychotherapy not only has positive but also negative effects, which is especially true for group psychotherapy due to psychodynamic and interactional processes. Using the UE-G questionnaire 71 patients who participated in cognitive behavioral group psychotherapy reported on negative experiences in the context of the group therapy. The answers were then validated in a qualitative interview. Of the patients 98.6% reported about at least one negative experience and 43.7% about severe or extremely severe negative experiences. Most prominent was the induction of hopelessness and demoralization by what patients saw and heard from other patients in the group. Burdensome and therefore undesired treatment effects are regularly seen in group psychotherapy, because of treatment or patient related factors. In any case they must be taken into account during treatment, in the training of group psychotherapists and in quality control.

  8. Effect of different treatments on breaking dormancy of Teucrium polium

    Directory of Open Access Journals (Sweden)

    alireza koochaki

    2009-06-01

    Full Text Available In order to evaluate effects of different treatments on breaking dormancy of Teucrium polium, an experiment was conducted with 3 replications in a completely randomized design. Seeds were subjected to different treatments including various levels of GA3, H2SO4, soaking with water and chilling. Germination of Teucrium polium increased with different concentrations of GA3. Percentage germination Maximum and rate was obtained at concentrations of 250, 1500 ppm (72h GA3 and combination of GA3 (1500ppm and chilling (5 ºC for a period of 14 days. GA3 (500ppm increased germination percentage but not germination rate. Soaking with water broke dormancy and induced 32% seed germination of Teucrium polium, but H2SO4, freezing (-10 ºC and combination of both treatments had no effect on dormancy.

  9. Neuroimaging the Effectiveness of Substance Use Disorder Treatments.

    Science.gov (United States)

    Cabrera, Elizabeth A; Wiers, Corinde E; Lindgren, Elsa; Miller, Gregg; Volkow, Nora D; Wang, Gene-Jack

    2016-09-01

    Neuroimaging techniques to measure the function and biochemistry of the human brain such as positron emission tomography (PET), proton magnetic resonance spectroscopy ((1)H MRS), and functional magnetic resonance imaging (fMRI), are powerful tools for assessing neurobiological mechanisms underlying the response to treatments in substance use disorders. Here, we review the neuroimaging literature on pharmacological and behavioral treatment in substance use disorder. We focus on neural effects of medications that reduce craving (e.g., naltrexone, bupropion hydrochloride, baclofen, methadone, varenicline) and that improve cognitive control (e.g., modafinil, N-acetylcysteine), of behavioral treatments for substance use disorders (e.g., cognitive bias modification training, virtual reality, motivational interventions) and neuromodulatory interventions such as neurofeedback and transcranial magnetic stimulation. A consistent finding for the effectiveness of therapeutic interventions identifies the improvement of executive control networks and the dampening of limbic activation, highlighting their values as targets for therapeutic interventions in substance use disorders.

  10. Effectiveness of botulinum toxin A in treatment of refractory erythromelalgia

    Directory of Open Access Journals (Sweden)

    Kuan-Hsiang Lin

    2013-05-01

    Full Text Available Erythromelalgia is characterized by intense burning pain, erythema, and heat in affected areas after precipitating factors such as warm temperature or stress. It is refractory to treatment in some situations. We describe a woman with adenosquamous cell carcinoma of the lung and medically refractory erythromelalgia. The symptoms of erythromelalgia presented as refractory to any medical treatment. Due to the unresponsive nature of her condition, botulinum toxin type A (onabotulinumtoxin A was injected over both of her cheeks, periodically for six cycles. Her symptoms responded dramatically to subcutaneous and intradermal injection of botulinum toxin type A. Repetitive injection demonstrated consistent and reproducible responses, and the efficacy was maintained for approximately 1 month. No adverse effects or complications were noted. Botulinum toxin type A might be safe and effective as an alternative treatment for refractory erythromelalgia, but further large-scale studies are required.

  11. Effect of hydrothermal treatment on some properties of Shenhua coal

    Energy Technology Data Exchange (ETDEWEB)

    Wang Zhi-cai; Shui Heng-fu; Zhang De-xiang; Gao Jin-sheng [East China University of Science and Technology, Shanghai (China). College of Resource and Environmental Engineering

    2006-10-15

    Effects of hydrothermal treatment on swelling, extraction and liquefaction behavior of Shenhua coal were studied through analyses of element content, ash content, volatile content and IR spectrum of treated coal. The results indicate that hydrogenation of coal is distinctly carried out in the process of hydrothermal pre-treatment and the hydrogen content of treated coal is more than that of raw coal. The contents of ash and volatile matters of treated coal are lower than those of raw coal. With the increase of treatment temperature the volatile content of the hydrothermal treated coal decreases and the ash content of treated coal increases. CO{sub 2} is main gas product and unvaries with the temperature changing, whereas CO and CH{sub 4} are formed when the temperature is above 250{sup o}C and increase with the temperature during hydrothermal treatment. Hydrothermal treatment is not in favor of coal swelling and the swelling ratio of treated coal decreases with the increase of treatment temperature. The swelling ratio of extraction residue by CS{sub 2}/NMP mixed solvent in NMP solvent is lower than that of the corresponding raw coal. The CS{sub 2}/NMP mixed solvent extraction yields of coal treated at appropriate temperature are higher than that of raw coal, but the extraction yields of treated coal obtained by n-hexane, toluene and THF successive Soxhelt extraction are lower. Hydrothermal treatment at 250-300{sup o}C can increase the conversion of treated coal in direct hydro-liquefaction. The gas + oil yield of treated coal is lower than that of raw coal and the preasphaltene yield of treated coal is much higher. IR spectra of treated coals show that the forms of non-covalent bonds are changed by hydrothermal treatment, and the hydrolysis of ester and ether bonds and the pyrolysis of aromatic side chains also maybe occur at high treatment temperature. 21 refs., 3 figs., 4 tabs.

  12. The Cost-Effectiveness of Treatment Modalities for Ureteral Stones

    Directory of Open Access Journals (Sweden)

    Justin Ji-Yuen Siu MD

    2016-10-01

    Full Text Available Additional intervention and medical treatment of complications may follow the primary treatment of a ureteral stone. We investigated the cost of the treatment of ureteral stone(s within 45 days after initial intervention by means of retrospective analysis of the National Health Insurance Research Database of Taiwan. All patients of ages ≥20 years diagnosed with ureteral stone(s( International Classification of Diseases, Ninth Revision, Clinical Modification/ICD-9-CM: 592.1 from January 2001 to December 2011 were enrolled. We included a comorbidity code only if the diagnosis appeared in at least 2 separate claims in a patient’s record. Treatment modalities (code included extracorporeal shock-wave lithotripsy (SWL; 98.51, ureteroscopic lithotripsy (URSL; 56.31, percutaneous nephrolithotripsy (PNL; 55.04, (open ureterolithotomy (56.20, and laparoscopy (ie, laparoscopic ureterolithotomy; 54.21. There were 28 513 patients with ureteral stones (13 848 men and 14 665 women in the randomized sample of 1 million patients. The mean cost was 526.4 ± 724.1 United States Dollar (USD. The costs of treatment were significantly increased in patients with comorbidities. The costs of treatment among each primary treatment modalities were 1212.2 ± 627.3, 1146.7 ± 816.8, 2507.4 ± 1333.5, 1533.3 ± 1137.1, 2566.4 ± 2594.3, and 209.8 ± 473.2 USD in the SWL, URSL, PNL, (open ureterolithotomy, laparoscopy (laparoscopic ureterolithotomy, and conservative treatment group, respectively. In conclusion, URSL was more cost-effective than SWL and PNL as a primary treatment modality for ureteral stone(s when the possible additional costs within 45 days after the initial operation were included in the calculation.

  13. Periodic Discordance Between Vote Equality and Representational Equality in the United States

    Directory of Open Access Journals (Sweden)

    Sarah K. Cowan

    2015-08-01

    Full Text Available American democracy has two central values that are often in tension: vote equality, that each vote has equal influence, and representational equality, that each elected official represents equal numbers of people. The electoral standard of “one person, one vote” ensures representational equality, and that often ensures vote equality. This relationship fails, however, under certain demographic conditions, namely, when a large, non-enfranchised population resides unevenly across jurisdictions. Then, representational equality is preserved and vote equality is violated. Prior to women’s suffrage, for example, western states had relatively fewer women than the remainder of the country, contributing to gross vote inequality, though rectified through extension of the franchise. Given recent high rates of immigration to some states, I ask whether the two values are in tension. I find that they are, and quantify the electoral consequences of this disjuncture at 13 House seats in 2010.

  14. EFFECTIVENESS AND SAFETY OF RECOMBINANT HUMAN GRANULOCYTIC COLONY-STIMULATING FACTOR IN TREATMENT OF GRANULOCYTOPENIA DEVELOPED DURING IMMUNOSUPPRESSIVE THERAPY IN PATIENTS WITH JUVENILE RHEUMATOID ARTHRITIS

    Directory of Open Access Journals (Sweden)

    E.I. Alexeeva

    2010-01-01

    Full Text Available Treatment of patients with severe clinical course of juvenile rheumatoid arthritis (JRA is difficult problem. During the last years genetically engineered biological drugs are used equally with traditional immunosuppressive agents in treatment of severe forms of juvenile arthritis. High effectiveness of these drugs can be accompanied with development of unfavorable effects, for example, febrile neutropenia. The article presents results of a study of effectiveness and safety of recombinant human granulocytic colony-stimulating factor — filgrastim (Leucostim — in treatment of granulocytopenia developed during immunosuppressive therapy in 16 patients with JRA. It was shown that administration of filgrastim arrests leucopenia in 100% of patients and granulocytopenia — in 93% of patients in 24 hours after first injection. High effectiveness of drug was combined with good tolerability and safety.Key words: children, treatment, granulocytopenia, filgrastim, juvenile rheumatoid arthritis.(Voprosy sovremennoi pediatrii — Current Pediatrics. – 2010;9(4:94-100

  15. Effects of sulphuric acid and hot water treatments on seed ...

    African Journals Online (AJOL)

    A study was carried out to investigate the effects of sulphuric acid and hot water treatments on the germination of Tamarind (Tamarindus indica L). Seeds were placed on moistened filter papers in 28 cm diameter Petri dishes under laboratory condition for germination. 330 seeds of T. indica (10 seeds per Petri dish) with ...

  16. The effect of different treatments on improving seed germination ...

    African Journals Online (AJOL)

    Creating optimal conditions for germination of medicinal plants seed is essential for their cultivation. Therefore, to evaluate the effect of different treatments on seed germination of two medicinal species, Descurainia sophia and Plantago ovata collected in 2009 from Tehran Province, an experiment with a factorial ...

  17. Heat treatment effect on impact strength of 40Kh steel

    International Nuclear Information System (INIS)

    Golubev, V.K.; Novikov, S.A.; Sobolev, Yu.S.; Yukina, N.A.

    1984-01-01

    The paper presents results of studies on the effect of heat treatment on strength and pattern of 40Kh steel impact failure. Loading levels corresponding to macroscopic spalling microdamage initiation in the material are determined for three initial states. Metallographic study on the spalling failure pattern for 40Kh steel in different initial states and data on microhardness measurement are presented

  18. The Effect of Hydrothermal Treatment on Olivine Nano-Silica

    NARCIS (Netherlands)

    Griend, van de M.C; Lazaro, A.; Brouwers, H.J.H.

    2012-01-01

    This paper provides an overview of the effects of ripening the olivine nano-silica to form particles with a lower specific surface area for optimal use in high performance concrete. The nano-silica was ripened using a hydrothermal treatment in a mixed batch reactor at 90 C, pH ranging from 8 to 10

  19. The effects of heat treatment on physical and technological ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-10-19

    Oct 19, 2009 ... ween 450 and 660 m altitudes in Cide-Sehdagi (Gercek et al., 1998; Dogu ... changes continue as the temperature is increased in ... Heat treatment slows water uptake and wood cell wall absorbs ...... The Effect of Boiling Time.

  20. Effect of packaging and chemical treatment on storage life and ...

    African Journals Online (AJOL)

    Fresh fruits and vegetables are inherently more liable to deterioration under tropical conditions characterized by high ambient temperatures and humidity. In determining the effects of chemical treatment on tomatoes (Lycopersicon esculentum Mill cv. Roma), fruits purchased at turning stage of ripening were packaged in low ...

  1. Effect of zinc treatment on intestinal motility in experimentally ...

    African Journals Online (AJOL)

    Effect of zinc treatment on intestinal motility in experimentally induced diarrhea in rats. ... Zinc supplementation is a critical new intervention for treating diarrheal episodes in children. Recent studies suggest that administration of zinc along with new low osmolarity oral rehydration solutions / salts (ORS) can reduce the ...

  2. Apathy in Alzheimer’s Disease: Any Effective Treatment?

    Directory of Open Access Journals (Sweden)

    Raffaele Rea

    2014-01-01

    Full Text Available Objective. This review has evaluated the effectiveness of pharmacological treatment of apathy in patients with Alzheimer’s disease (AD. Methods. A systematic literature search was conducted on published clinical trials assessing the effects of pharmacological treatment on apathy in AD over the last 10 years. Results. Fourteen studies considered of good quality were included in the analysis (4 randomized controlled trials, 9 open-label studies, and 1 retrospective analysis. Cholinesterase inhibitors were investigated in 9 studies, monoaminergic compounds such as methylphenidate and modafinil in two trials and one trial, respectively, and Ginkgo biloba (EGb 761 extract and citalopram in one study each. Cholinesterase inhibitors did not show statistical significant effect in 1 RCT study but were associated to improvement in 3 open-label studies. Methylphenidate elicited a small but significant activity accompanied by relevant side effects such as high blood pressure, cough, and osteoarticular pain. EGb 761 was well tolerated and countered apathy. Other treatments induced modest improvements or were ineffective. Conclusions. Apathy treatment remains a challenge and there is no evident advantage of any specific pharmacotherapy tested so far. The development of controlled studies according to updated guidelines for the diagnosis of apathy in patients with AD is desirable.

  3. The effects of heat treatment on physical and technological ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-10-19

    Oct 19, 2009 ... surface of wood were used to evaluate the effect of heat treatment on the surface characteristics of ... Some of the products developed by thermal treat- .... boards were stored uncontrolled condition in an unheated room for .... These results can be explained with material loses in ...... Finland-state of the art.

  4. Rapid bioassessment of the effects of repeated rotenone treatments ...

    African Journals Online (AJOL)

    The potential collateral effects of eradicating invasive fishes in streams necessitate the monitoring of invertebrate communities during treatment. In an environmental rehabilitation programme, non-native smallmouth bass were removed from the lower reaches of the Rondegat River, Western Cape, South Africa, in 2012 and ...

  5. Effects of glycyrrhizin pre-treatment on transient ischemic brain ...

    African Journals Online (AJOL)

    Effects of glycyrrhizin pre-treatment on transient ischemic brain injury in mice. ... on transient ischemic brain injury in mice. Chiyeon Lim, Sehyun Lim, Young-Jun Lee, Bokcheul Kong, Byoungho Lee, Chang-Hyun Kim, Buyeo Kim, Suin Cho ... induced brain damage. Keywords: Glycyrrhizin, licorice, stroke, apoptosis ...

  6. Effects of co-treatment of Rauwolfia vomitoria and Gongronema ...

    African Journals Online (AJOL)

    Effects of co-treatment of Rauwolfia vomitoria and Gongronema latifolium on neurobehaviour and the neurohistology of the cerebral cortex in mice. ... Light and dark field behaviour test was carried out on day 8 and the animals were immediately sacrificed. Their brains were excised and routinely processed by haematoxylin ...

  7. Effect of normabaric hyperoxia treatment on neuronal damage ...

    Indian Academy of Sciences (India)

    Traumatic brain injury (TBI) causes significant mortality in most developing countries worldwide. At present, it is imperative to identify a treatment to address the devastating post-TBI consequences. Therefore, the present study has been performed to assess the specific effect of immediate exposure to normabaric hyperoxia ...

  8. THE EFFECTS OF INTERCRITICAL HEAT TREATMENTS ON THE ...

    African Journals Online (AJOL)

    Effect of intercritical heat treatment on 0.14wt%C 0.56wt%Mn 0.13wt%Si struc- ... Table 1: Chemical composition of the steel used (wt. %) with its critical temperature (calculated). C. Mn. Si. Ni. S ... primary austenitic grain size hardening and.

  9. Effect of substrate type, dopant and thermal treatment on ...

    Indian Academy of Sciences (India)

    Effect of substrate type, dopant and thermal treatment on physicochemical properties of TiO2–SnO2 sol–gel films. I STAMBOLOVA. ∗. , V BLASKOV, S VASSILEV†, M SHIPOCHKA and A LOUKANOV‡. Institute of General and Inorganic Chemistry, †Institute of Electrochemistry and Energy Systems, BAS,. Acad. G. Bonchev ...

  10. Effect of heat treatment on polyphenol oxidase and peroxidase ...

    African Journals Online (AJOL)

    Effect of heat treatment (55°C/20 min) on polyphenol oxidase (PPO) and peroxidase (POD) activities and total phenolic compounds was investigated in Algerian dates (Deglet Nour variety) at Tamar (fully ripe) stage and in dates stored for 5 months at ambient temperature and in cold storage (10°C). Results obtained ...

  11. Effects of Mulching, Fertilizer, Seeding and Seedling Treatments on ...

    African Journals Online (AJOL)

    Effects of Mulching, Fertilizer, Seeding and Seedling Treatments on Plant Species Recovery in Kondoa Irangi Hills, Tanzania. ... There were high significant correlations of 0.85 and 0.87 between seedling recruitment and mortality in both sites, indicating that other factors, probably aridity, rather than prevailing site conditions ...

  12. The effect of atmospheric corona treatment on AA1050 aluminium

    DEFF Research Database (Denmark)

    Jariyaboon, Manthana; Møller, Per; Dunin-Borkowski, Rafal E.

    2010-01-01

    The effect of atmospheric corona discharge on AM 050 aluminium surface was investigated using electrochemical polarization, SEM-EDX, FIB-SEM. and XPS. The corona treatment was performed with varying time (1, 5, and 15 min) in atmospheric air. A 200 nm oxide layer was generated on AA1050 after...

  13. Relative Effectiveness of Three Modes of Treatment on English ...

    African Journals Online (AJOL)

    This study examined the effectiveness of Study Skill Counselling (SSC), Rational Emotive Therapy (RET), and a combined treatment of SSC & RET in improving the performance of students in English Language. Forty students in SS II class were randomly selected and assigned to the three experimental groups and control ...

  14. Effects of Video Modeling on Treatment Integrity of Behavioral Interventions

    Science.gov (United States)

    DiGennaro-Reed, Florence D.; Codding, Robin; Catania, Cynthia N.; Maguire, Helena

    2010-01-01

    We examined the effects of individualized video modeling on the accurate implementation of behavioral interventions using a multiple baseline design across 3 teachers. During video modeling, treatment integrity improved above baseline levels; however, teacher performance remained variable. The addition of verbal performance feedback increased…

  15. Effects of Acid treatment on the compression and mechanical ...

    African Journals Online (AJOL)

    This study investigated the effect of acid treatment on the compression and mechanical properties of the cellulosic fibrous residue obtained after a high proportion of starch has been removed from the peeled and rasped tuberous root of Xanthosoma sagittifolium (Family: Araceae). Powdered fibrous residues were subjected ...

  16. Impact of bovine subclinical mastitis and effect of lactational treatment

    NARCIS (Netherlands)

    van den Borne, B.H.P.|info:eu-repo/dai/nl/304836826

    2010-01-01

    This thesis aimed to quantify the impact of subclinical mastitis in dairy cattle in the Netherlands and to explore the epidemiologic and economic effects of antimicrobial treatment of recently acquired subclinical mastitis during lactation. First, the occurrence of (sub)clinical mastitis was

  17. Effects of different rhizosphere ventilation treatment on water and ...

    African Journals Online (AJOL)

    The objective of this study was to explore the effects of different rhizosphere ventilation treatment on water and nutrients absorption of maize. The pot experiment was conducted using three methods: no ventilation, two day ventilation and four day ventilation, under conditions of the different levels of irrigation methods.

  18. PERMEABLE TREATMENT WALL EFFECTIVENESS MONITORING PROJECT, NEVADA STEWART MINE

    Science.gov (United States)

    This report summarizes the results of Mine Waste Technology Program (MWTP) Activity III, Project 39, Permeable Treatment Wall Effectiveness Monitoring Project, implemented and funded by the U.S. Environmental Protection Agency (EPA) and jointly administered by EPA and the U.S. De...

  19. Effect of protein supplementation and urea treatment on utilization of ...

    African Journals Online (AJOL)

    Authorised User

    Abstract. Six Red Maasai sheep were used to investigate the effects of urea treatment and cotton seed cake supplementation of maize stover on intake, digestibility and rumen fermentation parameters. The basal feeds were Rhodes grass (Chloris gayana) hay (H), untreated maize (Zea mays) stover (US) and treated maize.

  20. Effects Of Desensitization Treatment On Core-Condition Training

    Science.gov (United States)

    Fry, P. S.

    1973-01-01

    Pre- and posttest ratings on measures of helping skills such as empathy, respect, concreteness, and genuineness were obtained in the preliminary and advanced training. A significant training effect was obtained for both groups. Desensitization treatment was a significant source of variance for the experimental subjects in training. (Author/LA)

  1. Effects of heat treatment on density, dimensional stability and color ...

    African Journals Online (AJOL)

    The purpose of this study was to evaluate the effect of heat treatment on some physical properties and color change of Pinus nigra wood which has high industrial use potential and large growing stocks in Turkey. Wood samples which comprised the material of the study were obtained from an industrial plant. Samples were ...

  2. Assessing Instructional Modalities: Individualized Treatment Effects for Personalized Learning

    Science.gov (United States)

    Beemer, Joshua; Spoon, Kelly; Fan, Juanjuan; Stronach, Jeanne; Frazee, James P.; Bohonak, Andrew J.; Levine, Richard A.

    2018-01-01

    Estimating the efficacy of different instructional modalities, techniques, and interventions is challenging because teaching style covaries with instructor, and the typical student only takes a course once. We introduce the individualized treatment effect (ITE) from analyses of personalized medicine as a means to quantify individual student…

  3. A study of the effects of internal organ motion on dose escalation in conformal prostate treatments

    International Nuclear Information System (INIS)

    Happersett, Laura; Mageras, Gig S.; Zelefsky, Michael J.; Burman, Chandra M.; Leibel, Steven A.; Chui Chen; Fuks, Zvi; Bull, Sarah; Ling, C. Clifton; Kutcher, Gerald J.

    2003-01-01

    Background and purpose: To assess the effect of internal organ motion on the dose distributions and biological indices for the target and non-target organs for three different conformal prostate treatment techniques. Materials and methods: We examined three types of treatment plans in 20 patients: (1) a six field plan, with a prescribed dose of 75.6 Gy; (2) the same six field plan to 72 Gy followed by a boost to 81 Gy; and (3) a five field plan with intensity modulated beams delivering 81 Gy. Treatment plans were designed using an initial CT data set (planning) and applied to three subsequent CT scans (treatment). The treatment CT contours were used to represent patient specific organ displacement; in addition, the dose distribution was convolved with a Gaussian distribution to model random setup error. Dose-volume histograms were calculated using an organ deformation model in which the movement between scans of individual points interior to the organs was tracked and the dose accumulated. The tumor control probability (TCP) for the prostate and proximal half of seminal vesicles (clinical target volume, CTV), normal tissue complication probability (NTCP) for the rectum and the percent volume of bladder wall receiving at least 75 Gy were calculated. Results: The patient averaged increase in the planned TCP between plan types 2 and 1 and types 3 and 1 was 9.8% (range 4.9-12.5%) for both, whereas the corresponding increases in treatment TCP were 9.0% (1.3-16%) and 8.1% (-1.3-13.8%). In all patients, plans 2 and 3 (81 Gy) exhibited equal or higher treatment TCP than plan 1 (75.6 Gy). The maximum treatment NTCP for rectum never exceeded the planning constraint and percent volume of bladder wall receiving at least 75 Gy was similar in the planning and treatment scans for all three plans. Conclusion: For plans that deliver a uniform prescribed dose to the planning target volume (PTV) (plan 1), current margins are adequate. In plans that further escalate the dose to part

  4. Modelling the cost effectiveness of antidepressant treatment in primary care.

    Science.gov (United States)

    Revicki, D A; Brown, R E; Palmer, W; Bakish, D; Rosser, W W; Anton, S F; Feeny, D

    1995-12-01

    The aim of this study was to estimate the cost effectiveness of nefazodone compared with imipramine or fluoxetine in treating women with major depressive disorder. Clinical decision analysis and a Markov state-transition model were used to estimate the lifetime health outcomes and medical costs of 3 antidepressant treatments. The model, which represents ideal primary care practice, compares treatment with nefazodone to treatment with either imipramine or fluoxetine. The economic analysis was based on the healthcare system of the Canadian province of Ontario, and considered only direct medical costs. Health outcomes were expressed as quality-adjusted life years (QALYs) and costs were in 1993 Canadian dollars ($Can; $Can1 = $US0.75, September 1995). Incremental cost-utility ratios were calculated comparing the relative lifetime discounted medical costs and QALYs associated with nefazodone with those of imipramine or fluoxetine. Data for constructing the model and estimating necessary parameters were derived from the medical literature, clinical trial data, and physician judgement. Data included information on: Ontario primary care physicians' clinical management of major depression; medical resource use and costs; probabilities of recurrence of depression; suicide rates; compliance rates; and health utilities. Estimates of utilities for depression-related hypothetical health states were obtained from patients with major depression (n = 70). Medical costs and QALYs were discounted to present value using a 5% rate. Sensitivity analyses tested the assumptions of the model by varying the discount rate, depression recurrence rates, compliance rates, and the duration of the model. The base case analysis found that nefazodone treatment costs $Can1447 less per patient than imipramine treatment (discounted lifetime medical costs were $Can50,664 vs $Can52,111) and increases the number of QALYs by 0.72 (13.90 vs 13.18). Nefazodone treatment costs $Can14 less than fluoxetine

  5. FINANCIAL EQUALIZATION TRANSFERS BETWEEN PUBLIC AUTHORITIES BUDGETS

    Directory of Open Access Journals (Sweden)

    Emilia Cornelia STOICA

    2015-07-01

    Full Text Available This paper presents financial balancing mechanisms that it is applied by the most of the states with competitive market economy, in order to ensure equity between local authorities, as well as the stability of the entire national tax and budgetary system. In this regard, it is described the concept of financial equalization and its structure according to two fundamental criteria: - equalization in accordance with the financial transfers orientation, distinguishing thus (1 horizontal equalization, which is carried out between local authorities and consists in assigning a part of the richest territorial collectivities resources to the disadvantaged ones; (2 vertical financial equalization, achieved through consolidated transfers the state / federal budget to the budgets by territorial administrative units, both for the operating budget section and for the development one; - financial equalization according to the regional or local disparities observed as a result of territorial-level analyzes: (1 financial equalization based on balancing public revenues of the administrative-territorial units, which tries to correct the differences between the financial resources of each local authority and (2 the financial balancing based on the costs, which aims to reduce differences between standard costs of public services per capita. Financial equalization mechanisms have as main objective the reduction as far as the total elimination of the regional or local disparities, which are also described in this article.

  6. Effectiveness of an intensive multidisciplinary headache treatment program.

    Science.gov (United States)

    Gunreben-Stempfle, Birgit; Griessinger, Norbert; Lang, Eberhard; Muehlhans, Barbara; Sittl, Reinhard; Ulrich, Kathrin

    2009-07-01

    To investigate if the effectiveness of a 96-hour multidisciplinary headache treatment program exceeds the effectiveness of a 20-hour program and primary care. When dealing with chronic back pain, low-intensity multidisciplinary treatment yields no significantly better results than standard care and monodisciplinary therapy; however, high-intensity treatment does. For multidisciplinary headache treatment, such comparisons are not yet available. In a previous study undertaken by our Pain Center, the outcome of a minimal multidisciplinary intervention model (20-hour) did not exceed primary care. Forty-two patients suffering from frequent headaches (20 +/- 9 headache days/month; range: 8-30) were treated and evaluated in a 96-hour group program. The results were compared with the outcomes of the previous study. Subjects who had undergone either the 20-hour multidisciplinary program or the primary care were used as historical control groups. A significant reduction in migraine days (P tension-type headache days (P tension-type headache days (P = .016), and frequency of migraine attacks (P = .016). In comparison with the 20-hour multidisciplinary program, the 96-hour program showed significantly better effects only in the reduction of migraine days (P = .037) and depression score (P = .003). The responder-rates (> or =50% improvement) in the 96-hour program were significantly higher than in the 20-hour program (migraine days, P = .008; tension-type headache days, P = .044) and primary care (migraine days, P = .007; tension-type headache days, P = .003; tension-type headache intensity, P = .037). The effect sizes were small to medium in the 96-hour program. Particularly with the reduction of migraine symptomatology, the 96-hour program performed better than the 20-hour program, which produced only negligible or small effects. Intensive multidisciplinary headache treatment is highly effective for patients with chronic headaches. Furthermore, migraine symptomatology

  7. Effectiveness of integrating individualized and generic complementary medicine treatments with standard care versus standard care alone for reducing preoperative anxiety.

    Science.gov (United States)

    Attias, Samuel; Keinan Boker, Lital; Arnon, Zahi; Ben-Arye, Eran; Bar'am, Ayala; Sroka, Gideon; Matter, Ibrahim; Somri, Mostafa; Schiff, Elad

    2016-03-01

    Preoperative anxiety is commonly reported by people undergoing surgery. A significant number of studies have found a correlation between preoperative anxiety and post-operative morbidity. Various methods of complementary and alternative medicine (CAM) were found to be effective in alleviating preoperative anxiety. This study examined the relative effectiveness of various individual and generic CAM methods combined with standard treatment (ST) in relieving preoperative anxiety, in comparison with ST alone. Randomized controlled trial. Holding room area Three hundred sixty patients. Patients were randomly divided into 6 equal-sized groups. Group 1 received the standard treatment (ST) for anxiety alleviation with anxiolytics. The five other groups received the following, together with ST (anxiolytics): Compact Disk Recording of Guided Imagery (CDRGI); acupuncture; individual guided imagery; reflexology; and individual guided imagery combined with reflexology, based on medical staff availability. Assessment of anxiety was taken upon entering the holding room area (surgery preparation room) ('pre-treatment assessment'), and following the treatment, shortly before transfer to the operating room ('post-treatment assessment'), based on the Visual Analogue Scale (VAS) questionnaire. Data processing included comparison of VAS averages in the 'pre' and 'post' stages among the various groups. Preoperatively, CAM treatments were associated with significant reduction of anxiety level (5.54-2.32, peffective than individualized CAM (Peffective than generic CDRGI. In light of the scope of preoperative anxiety and its implications for public health, integration of CAM therapies with ST should be considered for reducing preoperative anxiety. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. Equality Hypocrisy, Inconsistency, and Prejudice: The Unequal Application of the Universal Human Right to Equality

    Science.gov (United States)

    2015-01-01

    In Western culture, there appears to be widespread endorsement of Article 1 of the Universal Declaration of Human Rights (which stresses equality and freedom). But do people really apply their equality values equally, or are their principles and application systematically discrepant, resulting in equality hypocrisy? The present study, conducted with a representative national sample of adults in the United Kingdom (N = 2,895), provides the first societal test of whether people apply their value of “equality for all” similarly across multiple types of status minority (women, disabled people, people aged over 70, Blacks, Muslims, and gay people). Drawing on theories of intergroup relations and stereotyping we examined, relation to each of these groups, respondents’ judgments of how important it is to satisfy their particular wishes, whether there should be greater or reduced equality of employment opportunities, and feelings of social distance. The data revealed a clear gap between general equality values and responses to these specific measures. Respondents prioritized equality more for “paternalized” groups (targets of benevolent prejudice: women, disabled, over 70) than others (Black people, Muslims, and homosexual people), demonstrating significant inconsistency. Respondents who valued equality more, or who expressed higher internal or external motivation to control prejudice, showed greater consistency in applying equality. However, even respondents who valued equality highly showed significant divergence in their responses to paternalized versus nonpaternalized groups, revealing a degree of hypocrisy. Implications for strategies to promote equality and challenge prejudice are discussed. PMID:25914516

  9. Equality Hypocrisy, Inconsistency, and Prejudice: The Unequal Application of the Universal Human Right to Equality.

    Science.gov (United States)

    Abrams, Dominic; Houston, Diane M; Van de Vyver, Julie; Vasiljevic, Milica

    2015-02-01

    In Western culture, there appears to be widespread endorsement of Article 1 of the Universal Declaration of Human Rights (which stresses equality and freedom). But do people really apply their equality values equally, or are their principles and application systematically discrepant, resulting in equality hypocrisy? The present study, conducted with a representative national sample of adults in the United Kingdom ( N = 2,895), provides the first societal test of whether people apply their value of "equality for all" similarly across multiple types of status minority (women, disabled people, people aged over 70, Blacks, Muslims, and gay people). Drawing on theories of intergroup relations and stereotyping we examined, relation to each of these groups, respondents' judgments of how important it is to satisfy their particular wishes, whether there should be greater or reduced equality of employment opportunities, and feelings of social distance. The data revealed a clear gap between general equality values and responses to these specific measures. Respondents prioritized equality more for "paternalized" groups (targets of benevolent prejudice: women, disabled, over 70) than others (Black people, Muslims, and homosexual people), demonstrating significant inconsistency. Respondents who valued equality more, or who expressed higher internal or external motivation to control prejudice, showed greater consistency in applying equality. However, even respondents who valued equality highly showed significant divergence in their responses to paternalized versus nonpaternalized groups, revealing a degree of hypocrisy. Implications for strategies to promote equality and challenge prejudice are discussed.

  10. Land Governance, Gender Equality and Development

    DEFF Research Database (Denmark)

    Ravnborg, Helle Munk; Spichiger, Rachel; Broegaard, Rikke Brandt

    2016-01-01

    pursued in these reforms and examines the role played by donor cooperation. Despite significant progress in developing land legislation that upholds gender equality, implementation often does not follow suit, and women still face discrimination. Based on country case studies, the article identifies six......Most land governance reforms seek to enhance tenure security, encourage investments and thereby promote economic growth. Increasingly, land reforms attempt to secure women's and other vulnerable groups' access to land. This article reviews the extent to which gender equality in land tenure has been...... challenges, which should be addressed to achieve gender equality in land tenure....

  11. Effectiveness of hypnosis therapy and Gestalt therapy as depression treatments

    Directory of Open Access Journals (Sweden)

    Elizabeth González-Ramírez

    2017-03-01

    Full Text Available We analyzed the effectiveness of two psychological therapies to treat depression in the Culiacan population, Mexico. According to criteria of MINI (international Neuropsychiatric interview, 30 individuals from a total of 300 were selected and diagnosed with some kind of depression. Patients were divided in three groups: 1 treatment with hypnosis therapy, 2 treatment with Gestalt-hypnosis therapy, and 3 control group. Before and after the treatments the Beck Anxiety Inventory (BAI was applied to know the depression level of the analyzed groups. The results show that the three groups were presenting a moderated level of depression. The groups under hypnosis therapy and Gestalt-hypnosis therapy show statistical differences between pre-test and post-test. The hypnosis therapy shows significant statistic differences to treat depression with respect to the other two groups. In conclusion, the therapeutic hypnosis is an effective treatment and has relevance to treat depression, while other therapeutic treatments tend to be slow and with minor result. This study is the first of this kind carried out in Culiacan in Sinaloa, Mexico.

  12. Effect of a standardized treatment regime for infection after osteosynthesis.

    Science.gov (United States)

    Hellebrekers, Pien; Leenen, Luke P H; Hoekstra, Meriam; Hietbrink, Falco

    2017-03-09

    Infection after osteosynthesis is an important complication with significant morbidity and even mortality. These infections are often caused by biofilm-producing bacteria. Treatment algorithms dictate an aggressive approach with surgical debridement and antibiotic treatment. The aim of this study is to analyze the effect of such an aggressive standardized treatment regime with implant retention for acute, existing regime consisted of implant retention, thorough surgical debridement, and immediate antibiotic combination therapy with rifampicin. The primary outcome was success. Success was defined as consolidation of the fracture and resolved symptoms of infection. Culture and susceptibility testing were performed to identify bacteria and resistance patterns. Univariate analysis was conducted on patient-related factors in association with primary success and antibiotic resistance. Forty-nine patients were included for analysis. The primary success rate was 63% and overall success rate 88%. Factors negatively associated with primary success were the following: Gustilo classification (P = 0.023), higher number of debridements needed (P = 0.015), inability of primary closure (P = 0.017), and subsequent application of vacuum therapy (P = 0.030). Adherence to the treatment regime was positively related to primary success (P = 0.034). The described treatment protocol results in high success rates, comparable with success rates achieved in staged exchange in prosthetic joint infection treatment.

  13. Individually dosed omalizumab: an effective treatment for severe peanut allergy.

    Science.gov (United States)

    Brandström, J; Vetander, M; Lilja, G; Johansson, S G O; Sundqvist, A-C; Kalm, F; Nilsson, C; Nopp, A

    2017-04-01

    Treatment with omalizumab has shown a positive effect on food allergies, but no dosages are established. Basophil allergen threshold sensitivity (CD-sens) can be used to objectively measure omalizumab treatment efficacy and correlates with the outcome of double-blind placebo-controlled food challenge to peanut. To evaluate whether individualized omalizumab treatment monitored by CD-sens could be an effective intervention for suppression of allergic reactions to peanut. Severely peanut allergic adolescents (n = 23) were treated with omalizumab for 8 weeks, and CD-sens was analysed before and after. Based on whether CD-sens was suppressed after 8 weeks, the patients either were subject to a peanut challenge or received eight more weeks with increased dose of omalizumab, followed by peanut challenge or another 8-week cycle of omalizumab. IgE and IgE-antibodies to peanut and its components were analysed before treatment. After individualized omalizumab treatment (8-24 weeks), all patients continued with an open peanut challenge with no (n = 18) or mild (n = 5) objective allergic symptoms. Patients (n = 15) needing an elevated omalizumab dose (ED) to suppress CD-sens had significantly higher CD-sens values at baseline 1.49 (0.44-20.5) compared to those (n = 8) who managed with normal dose (ND) 0.32 (0.24-5.5) (P omalizumab, monitored by CD-sens, is an effective and safe treatment for severe peanut allergy. The ratio of IgE-ab to storage protein Ara h 2/IgE as well as CD-sens to peanut may predict the need of a higher omalizumab dose. Clinical trials numbers: EudraCT; 2012-005625-78, ClinicalTrials.gov; NCT02402231. © 2016 John Wiley & Sons Ltd.

  14. Effect of the transpalatal arch during extraction treatment.

    Science.gov (United States)

    Zablocki, Heather L; McNamara, James A; Franchi, Lorenzo; Baccetti, Tiziano

    2008-06-01

    The transpalatal arch (TPA) can be used as an adjunct during orthodontic treatment to help control the movement of the maxillary first molars in 3 dimensions, including producing molar rotation and uprighting, maintaining transverse dimensions posteriorly during treatment, and maintaining leeway spaces during the transition of the dentition. The purpose of this retrospective cephalometric study was to test an additional function of the TPA: its ability to enhance orthodontic anchorage during extraction treatment. Records consisting of pretreatment and posttreatment cephalograms were gathered from several orthodontic practices that used an .018 x .025-in preangulated appliance. All patients were white and had 4 first premolars extracted as part of their treatment protocol. Patients were treated either with or without a TPA of the soldered Goshgarian design. Patients were excluded if headgear or any other auxiliary anchorage device beside the TPA was used during treatment. Matched samples of 30 patients were identified based on sex, age at the start of treatment, treatment duration, and cervical vertebral maturation stage. Statistical comparisons were made with nonparametric statistical tests. Analysis of the changes from pretreatment to posttreatment for the TPA and the no-TPA groups showed no statistically significant differences in any of the variables examined. The net difference for both vertical and mesial movement of the maxillary first molar in relation to the maxilla between the 2 groups was 0.4 mm, with the no-TPA group in a more downward and forward position. Although the usefulness of the TPA for the abovementioned functions is not negated, it does not provide a significant effect on either the anteroposterior or the vertical position of the maxillary first molars during extraction treatment.

  15. Cost-effectiveness in Clostridium difficile treatment decision-making.

    Science.gov (United States)

    Nuijten, Mark Jc; Keller, Josbert J; Visser, Caroline E; Redekop, Ken; Claassen, Eric; Speelman, Peter; Pronk, Marja H

    2015-11-16

    To develop a framework for the clinical and health economic assessment for management of Clostridium difficile infection (CDI). CDI has vast economic consequences emphasizing the need for innovative and cost effective solutions, which were aim of this study. A guidance model was developed for coverage decisions and guideline development in CDI. The model included pharmacotherapy with oral metronidazole or oral vancomycin, which is the mainstay for pharmacological treatment of CDI and is recommended by most treatment guidelines. A design for a patient-based cost-effectiveness model was developed, which can be used to estimate the cost-effectiveness of current and future treatment strategies in CDI. Patient-based outcomes were extrapolated to the population by including factors like, e.g., person-to-person transmission, isolation precautions and closing and cleaning wards of hospitals. The proposed framework for a population-based CDI model may be used for clinical and health economic assessments of CDI guidelines and coverage decisions for emerging treatments for CDI.

  16. Fenbendazole treatment may influence lipopolysaccharide effects in rat brain.

    Science.gov (United States)

    Hunter, Randy L; Choi, Dong-Young; Kincer, Jeanie F; Cass, Wayne A; Bing, Guoying; Gash, Don M

    2007-10-01

    In evaluating discrepant results between experiments in our laboratory, we collected data that challenge the notion that anthelminthic drugs like FBZ do not alter inflammatory responses. We found that FBZ significantly modulates inflammation in F344 rats intrastriatally injected with LPS. FBZ treatment of LPS-injected rats significantly increased weight loss, microglial activation, and dopamine loss; in addition, FBZ attenuated the LPS-induced loss of astrocytes. Therefore, FBZ treatment altered the effects of LPS injection. Caution should be used in interpreting data collected from rats treated with LPS and FBZ.

  17. Gender and occupational wage gaps in Romania: from planned equality to market inequality?

    OpenAIRE

    Andrén, Daniela; Andrén, Thomas

    2008-01-01

    In Romania, the communist regime promoted an official policy of gender equality for more than 40 years, providing equal access to education and employment, and restricting pay differentiation based on gender. After its fall in December 1989, the promotion of equal opportunities and treatment for women and men did not constitute a priority for any of the governments of the 1990s. This paper analyzes both gender and occupational wage gaps before and during the first years of transition to a mar...

  18. Effect of thermal treatment on potato starch evidenced by EPR, XRD and molecular weight distribution.

    Science.gov (United States)

    Bidzińska, Ewa; Michalec, Marek; Pawcenis, Dominika

    2015-12-01

    Effect of heating of the potato starch on damages of its structure was investigated by quantitative electron paramagnetic resonance (EPR) spectroscopy, X-ray diffraction and determination of the molecular weight distribution. The measurements were performed in the temperature range commonly used for starch modifications optimizing properties important for industrial applications. Upon thermal treatment, because of breaking of the polymer chains, diminishing of the average molecular weights occurred, which significantly influences generation of radicals, evidenced by EPR. For the relatively mild conditions, with heating parameters not exceeding temperature 230 °C and time of heating equal to 30 min a moderate changes of both the number of thermally generated radicals and the mean molecular weight of the starch were observed. After more drastic thermal treatment (e.g. 2 h at 230 °C), a rapid increase in the radical amount occurred, which was accompanied by significant reduction of the starch molecular size and crystallinity. Experimentally established threshold values of heating parameters should not be exceeded in order to avoid excessive damages of the starch structure accompanied by the formation of the redundant amount of radicals. This requirement is important for industrial applications, because significant destruction of the starch matrix might annihilate the positive influence of the previously performed intentional starch modification. Copyright © 2015 John Wiley & Sons, Ltd.

  19. Parameter trajectory analysis to identify treatment effects of pharmacological interventions.

    Directory of Open Access Journals (Sweden)

    Christian A Tiemann

    Full Text Available The field of medical systems biology aims to advance understanding of molecular mechanisms that drive disease progression and to translate this knowledge into therapies to effectively treat diseases. A challenging task is the investigation of long-term effects of a (pharmacological treatment, to establish its applicability and to identify potential side effects. We present a new modeling approach, called Analysis of Dynamic Adaptations in Parameter Trajectories (ADAPT, to analyze the long-term effects of a pharmacological intervention. A concept of time-dependent evolution of model parameters is introduced to study the dynamics of molecular adaptations. The progression of these adaptations is predicted by identifying necessary dynamic changes in the model parameters to describe the transition between experimental data obtained during different stages of the treatment. The trajectories provide insight in the affected underlying biological systems and identify the molecular events that should be studied in more detail to unravel the mechanistic basis of treatment outcome. Modulating effects caused by interactions with the proteome and transcriptome levels, which are often less well understood, can be captured by the time-dependent descriptions of the parameters. ADAPT was employed to identify metabolic adaptations induced upon pharmacological activation of the liver X receptor (LXR, a potential drug target to treat or prevent atherosclerosis. The trajectories were investigated to study the cascade of adaptations. This provided a counter-intuitive insight concerning the function of scavenger receptor class B1 (SR-B1, a receptor that facilitates the hepatic uptake of cholesterol. Although activation of LXR promotes cholesterol efflux and -excretion, our computational analysis showed that the hepatic capacity to clear cholesterol was reduced upon prolonged treatment. This prediction was confirmed experimentally by immunoblotting measurements of SR-B1

  20. The EEOC's New Equal Pay Act Guidelines.

    Science.gov (United States)

    Greenlaw, Paul S.; Kohl, John P.

    1982-01-01

    Analyzes the new guidelines for enforcement of the Equal Pay Act and their implications for personnel management. Argues that there are key problem areas in the new regulations arising from considerable ambiguity and uncertainty about their interpretation. (SK)

  1. Teaching the Economics of Equal Opportunities.

    Science.gov (United States)

    Ownby, Arnola C.; Rhea, Jeanine N.

    1990-01-01

    Focuses on equal opportunities--for education, pay, and with gender bias for individuals and business organizations. Suggests that business educators can expand the implications to include ethnic-based inequalities as well. (JOW)

  2. Equal Access to Justice Act Payments

    Data.gov (United States)

    Social Security Administration — A dataset containing payment amounts made by the Social Security Administration for court-approved Equal Access to Justice Act (EAJA) payments for fiscal year 2010...

  3. Girls' Education and Gender Equality. Factsheet

    Science.gov (United States)

    Global Partnership for Education, 2016

    2016-01-01

    This brief fact sheet presents benefits of investing in gender equality, how the Global Partnership for Education (GPE) supports inclusive and equitable quality education, as well as the results it has achieved.

  4. Gender equality mainstreaming: Implications for poverty reduction ...

    African Journals Online (AJOL)

    Gender equality mainstreaming: Implications for poverty reduction and sustainable development in Abia State of Nigeria. ... Empowerment of women when pursued beyond mere rhetoric and instrumentation, it will improve their wellbeing, self esteem, resource allocation, political voice and increased productivity generally.

  5. Valuing Equality in Irish Social Care

    Directory of Open Access Journals (Sweden)

    Niall Hanlon

    2009-01-01

    Full Text Available In this article the author critiques Irish social care by presenting an equality perspective on practice. An equality perspective involves developing emancipatory practices, that is, ways of helping that provide egalitarian solutions and outcomes. Although emancipatory values are often contrasted with traditional social care values, the author seeks a pragmatic and integrated approach to emancipatory practices rather than a restatement of traditional dichotomies. Emancipatory practice begins with an appreciation of the nature and relevance of inequalities on the lives of diverse social care users. Building a commitment to equality within social care education and practice is an important step in altering many individual and institutional social care practices by focussing on equality processes and outcomes as central social care objectives. Using a well credited framework that outlines five dimensions of inequality (Baker, Lynch, Cantillon and Walsh, 2004, the author argues that social care educators and practitioners need to debate the issues raised and develop emancipatory practices.

  6. ECONOMIC GROWTH AND EQUALITY IN REDUCING POVERTY

    Directory of Open Access Journals (Sweden)

    Zaenal Muttaqin

    2016-02-01

    Full Text Available In some developing countries, the instrument to alleviate the poverty is by using the economic growth. So, the increasing in investment, infrastructure development, and macroeconomics stability always be priority from developing countries. In this article explain that economic growth is not the important factor to alleviate the poverty, because equality sometimes is more important rather than the economic growth. In this context, its measure by inequality growth trade off index (IGTI. This method is to measure the influence of economic growth to reducing the inequality, with this method every country can measure which one is better to reducing the poverty whether the economic growth or equality. With this method, Laos in 2000 show that economic growth is more important than equality, but in the same year in Thailand show that equality is more important than economic growth.DOI: 10.15408/sjie.v1i1.2592

  7. Multicultural Challenges - new gender equality dilemmas

    DEFF Research Database (Denmark)

    Siim, Birte

    In my research have been interested in exploring tensions between diversity and gender equality from a theoretical and comparative approach, looking at the Nordic welfare, citizenship and gender regimes from a cross-national European perspective. In this key-note presentation I draw on results...... and inspiration from a number of comparative research projects and networks. In the following I address three issues that have been central in academic debates: 1) The challenges from multiculturalism to gender equality, 2) gendering citizenship and migration and 3) Nordic feminist debates about diversity....... In the last section I argue that one solution to the new gender equality dilemma posed by increased diversity among women is a simultaneous re-framing of multiculturalism and gender equality....

  8. Causality, spin, and equal-time commutators

    International Nuclear Information System (INIS)

    Abdel-Rahman, A.M.

    1975-01-01

    We study the causality constraints on the structure of the Lorentz-antisymmetric component of the commutator of two conserved isovector currents between fermion states of equal momenta. We discuss the sum rules that follow from causality and scaling, using the recently introduced refined infinite-momentum technique. The complete set of sum rules is found to include the spin-dependent fixed-mass sum rules obtained from light-cone commutators. The causality and scaling restrictions on the structure of the electromagnetic equal-time commutators are discussed, and it is found, in particular, that causality requires the spin-dependent part of the matrix element for the time-space electromagnetic equal-time commutator to vanish identically. It is also shown, in comparison with the electromagnetic case, that the corresponding matrix element for the time-space isovector current equal-time commutator is required, by causality, to have isospin-antisymmetric tensor and scalar operator Schwinger terms

  9. Equality of Opportunity for Well-Being

    DEFF Research Database (Denmark)

    Mahler, Daniel Gerszon; Ramos, Xavier

    2017-01-01

    A growing literature has tried to measure the extent to which individuals have equal opportunities to acquire income. At the same time, policy makers have doubled down on efforts to go beyond income when measuring well- being. We attempt to bridge these two areas by measuring the extent to which...... individuals have equal opportunities to achieve a high level of well-being. We use the German Socio-Economic Panel to measure well-being in four different ways including incomes. This makes it possible to determine if the way well-being is measured matters for identifying who the opportunity......-deprived are and for tracking inequality of opportunity over time. We find that, regardless of how well-being is measured, the same people are opportunity-deprived and equality of opportunity has improved over the past 20 years. This suggests that going beyond income has little relevance if the objective is to provide equal...

  10. Treatment of juvenile recurrent parotitis of childhood: an analysis of effectiveness.

    Science.gov (United States)

    Roby, Brianne Barnett; Mattingly, Jameson; Jensen, Emily L; Gao, Dexiang; Chan, Kenny H

    2015-02-01

    Juvenile recurrent parotitis (JRP) is characterized by recurrent painful swelling of the parotid gland that occurs in the pediatric population. Sialendoscopy with and without ductal corticosteroid infusion (DCI) has been found to be effective in the treatment of JRP and autoimmune parotitis. To determine the utility of instrumentation vs pharmacotherapy alone for juvenile recurrent parotitis. A retrospective medical record review of pediatric patients undergoing DCI without sialendoscopy at a tertiary pediatric hospital was conducted. The medical records were reviewed to determine the frequency of parotitis events before and after treatment. A multiquestion telephone survey of patients and their parents who underwent the procedure was then conducted to determine patient satisfaction. Ductal corticosteroid infusion with hydrocortisone through catheter inserted in the parotid duct. Frequency of symptoms before and after treatment and parental satisfaction with the treatment. Twelve patients with a mean age of 6.7 years were identified. The mean duration and frequency of symptoms before the procedure were 22 months and every 2 months, respectively. Five patients had a recurrence, on average 4 months after the procedure. Four patients underwent repeated surgical procedures. All had a longer duration between episodes compared with before DCI. Eight parents participated in the survey on satisfaction with the procedure, and 75% reported improvement in their child's life postprocedure. Current literature shows sialendoscopy with corticosteroid application is successful in treating JRP, but it is unclear whether corticosteroid application alone would treat JRP equally. This study shows that DCI alone has similar results as sialendoscopy with corticosteroid application, indicating that it is the corticosteroid application and not the sialendoscopy causing improvement in symptoms. Because JRP must be differentiated from sialolithiasis, we recommend ultrasonography of the

  11. Gender Equality, Intersectionality and Diversity in Europe

    DEFF Research Database (Denmark)

    Agustin, Lise Rolandsen

    . Drawing on discursive policy analysis, it addresses the interaction between policies, institutions and civil society actors in relation to gender equality, diversity and intersectionality at the European level. Rolandsen Agustín successfully integrates the concepts of diversity and gender equality...... into a contextualized approach to analyzing transnational intersectionality. This unique approach focuses on processes of institutionalization and mobilization, which are addressed in relation to the institutional setup of the EU, its policies and policymaking structures, as well as transnational civil society...

  12. Implementation of the Midway Image Equalization

    Directory of Open Access Journals (Sweden)

    Thierry Guillemot

    2016-06-01

    Full Text Available In this paper, we present the detailed algorithm of the Midway Image Equalization giving to a pair of images the same histogram while maintaining as much as possible their previous gray dynamics. The midway equalization is primarily designed for gray level images, but can be applied channel-wise to color images. This method is easy to implement, fast to compute, fully automatic and requires no parameter.

  13. Sweden: Combining childbearing and gender equality

    Directory of Open Access Journals (Sweden)

    Eva Bernhardt

    2008-07-01

    Full Text Available Sweden is the forerunner of the Second Demographic Transition. Fertility trends have fluctuated greatly since the 1960s, and the 1990s showed both European-highest and lowest-ever-in-Sweden levels, while the cohort pattern has been relatively stable. Period fluctuations have been accompanied by a postponement of entering committed partnerships and parenthood as well as an increasing instability of family relationships. The awareness and the availability of effective contraceptives have been extensive since the mid-1970s, the year the liberal abortion law was introduced. Post-modern values are dominant in this highly secularized society, but ideal family size is among the highest in the European Union, and childlessness has remained at a relatively low level. Ethnic diversification has increased over time, with about one-fifth of the population having a 'foreign background' in the early 2000s. The level of female labor-force participation is the highest in Europe (although mothers of pre-schoolers often work part-time, and young women are just as highly educated as men. Family policies, based on the principle of equality across social groups and gender, seem to play an important role in keeping fertility relatively high. In combination with other factors, family policies also play a role in the fluctuations of fertility rates, as eligibility to parental-leave and benefits as well as the availability of public childcare are linked to parents' labor-force attachment.

  14. [Gender equality activity in the Bioimaging Society].

    Science.gov (United States)

    Suzaki, Etsuko

    2013-09-01

    Gender equality activity in the Bioimaging Society was initiated in 2005 when it joined the Japan Inter-Society Liaison Association Committee for Promoting Equal Participation of Men and Women in Science and Engineering (EPMEWSE). The Gender Equality Committee of the Bioimaging Society is acting on this issue by following the policy of the EPMEWSE, and has also been planning and conducting lectures at annual meetings of the society to gain the understanding, consents, and cooperation of the members of the society to become conscious of gender equality. Women's participation in the society has been promoted through the activities of the Gender Equality Committee, and the number of women officers in the society has since increased from two women out of 40 members in 2005 to five out of 44 in 2013. The activities of the Gender Equality Committee of the Japanese Association of Anatomists (JAA) have just started. There are more than 400 women belonging to the JAA. When these women members join together and collaborate, women's participation in the JAA will increase.

  15. Marriage equality is a mental health issue.

    Science.gov (United States)

    Kealy-Bateman, Warren; Pryor, Lisa

    2015-10-01

    We aim to review marriage equality in New Zealand and Australia and critically evaluate the health impact of such a legal change. We undertook a review of the literature using the search terms "marriage equality", "same sex marriage" and "gay marriage" in combination with "health", "wellbeing", "psych*", "mental illness" and "distress". This search included medical literature, legal literature and mass media. This review indicates that Lesbian, Gay, Bisexual, Transgender and Intersex (LGBTI) people disproportionately face negative health stressors and negative health events compared with the general population and this is related to the stress of being a stigmatised minority group. The evidence strongly supports the proposition that marriage equality is related to improved health outcomes. A diverse range of professional health groups advocate for the legislative progression to marriage equality. The authors found no evidence that marriage equality harms opposite-sex marriage. Marriage equality is still lacking in Australia and as a positive correlate of health should be strongly supported. © The Royal Australian and New Zealand College of Psychiatrists 2015.

  16. Effects of Hyperbaric Oxygen Treatment on Renal System.

    Science.gov (United States)

    Tezcan, Orhan; Caliskan, Ahmet; Demirtas, Sinan; Yavuz, Celal; Kuyumcu, Mahir; Nergiz, Yusuf; Guzel, Abdulmenap; Karahan, Oguz; Ari, Seyhmus; Soker, Sevda; Yalinkilic, Ibrahim; Turkdogan, Kenan Ahmet

    2017-01-01

    Hyperbaric oxygen (HBO) treatment is steadily increasing as a therapeutic modality for various types of diseases. Although good clinical outcomes were reported with HBO treatment for various diseases, the multisystemic effects of this modality are still unclear. This study aimed to investigate the renal effects of HBO experimentally. Fourteen New Zealand White rabbits were divided into 2 groups randomly as the control group and the study group. The study group received HBO treatment for 28 days (100% oxygen at 2.5 atmospheres for 90 minutes daily) and the control group was used to obtain normal renal tissue of the animal genus. After the intervention period, venous blood samples were obtained, and renal tissue samples were harvested for comparisons. Normal histological morphology was determined with Masson trichrome staining and periodic acid-Schiff staining in the control group. Atrophic glomerular structures, vacuolated tubule cells, and degeneration were detected in the renal samples of the study group with Masson trichrome staining. Additionally, flattening was observed on the brush borders of the proximal tubules, and tubular dilatation was visualized with periodic acid-Schiff staining. The histopathologic disruption of renal morphology was verified with detection of significantly elevated kidney function laboratory biomarkers in the study group. Our findings suggests that HBO has adverse effects on renal glomerulus and proximal tubules. However, the functional effects of this alteration should be investigated with further studies.

  17. Effects of Topic Simvastatin for the Treatment of Chronic Vascular Cutaneous Ulcers: A Pilot Study.

    Science.gov (United States)

    Raposio, Edoardo; Libondi, Guido; Bertozzi, Nicolò; Grignaffini, Eugenio; Grieco, Michele P

    2015-12-01

    Recent research suggests that statins might be useful in the process of wound healing, playing a positive immune-modulatory role, improving microvascular function and reducing oxidative stress. The aim of this pilot study was to evaluate the efficacy of topic application of Simvastatin-based cream in the treatment of chronic vascular cutaneous ulcers, comparing this type of treatment to a collagen-based dressing, proven to be effective for ulcer treatment. A total of 20 ulcers were studied in 2 Groups of randomly-chosen patients for a period of one month. In the first Group a 0.5% Simvastatin-based cream was topically administered, while the second Group (control) was treated with an absorbable type I bovine collagen-based medication. Each week, wound healing progress was observed in both Groups, and the ulcers photographed. Wound healing rate was calculated by considering the absolute change in area and by the formula "healing ratio (%) = [(Area 0 - Area t4 )/Area 0 ] × 100," both sets of data being related to the days comprised in the study in order to calculate healing rate per day. Statistical analysis was performed by Student t test. Study endpoint equaling the time-course changes of ulcer areas. At the end of the study, when considering absolute change in area, the experimental Group appeared to heal better and faster than the control Group although differences between the Groups were not statistically significant. Conversely, rates of wound healing in the experimental and control Groups were 46.88% and 64% respectively, revealing statistically significant differences. ( P topic application of a simvastatin-based cream proved to be well- tolerated but not effective in the management of vascular leg ulcers in a 4 week-period.

  18. Equalities and Inequalities in the English Education System

    Science.gov (United States)

    Scott, David; Scott, Ben

    2018-01-01

    This book is about social categories such as gender, race, dis-ability, intelligence, sexuality and class, as they are used in education. Knowledge of and about them and their effects is central to how we can understand society, equalities and inequalities within it, and educational relations. The evidence to support the claims being made in this…

  19. The Equal Pay Act: The First 30 Years.

    Science.gov (United States)

    Crampton, Suzanne M.; Hodge, John W.; Mishra, Jitendra M.

    1997-01-01

    Analysis by decade of the effects of the Equal Pay Act of 1963 shows that women's earnings relative to men's increased by 10 cents from 1960-1990. Black and Hispanic women's earnings lagged further behind. More education and experience did not help women narrow the gap. (SK)

  20. Did School Finance Equalization Increase Revenue Instability for School Districts?

    Science.gov (United States)

    Balu, Rekha

    2011-01-01

    This study uses an Interrupted Time Series analysis with a non-equivalent comparison group to estimate the causal effect of school finance equalization on district revenue instability. The author applies a microeconomic framework to an understudied problem in education finance and policy. In so doing, she illustrates how policies can sometimes…