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Sample records for transportation underwriting systematic

  1. Cross-selling lending and underwriting : scope economies and incentives

    OpenAIRE

    Laux, Christian; Walz, Uwe

    2009-01-01

    We highlight the implications of combining underwriting services and lending for the choice of underwriters and for competition in the underwriting business. We show that cross-selling can increase underwriters' incentives, and we explain three phenomena: first, that cross-selling is important for universal banks to enter the investment banking business; second, that cross-selling is particularly attractive for highly leveraged borrowers; third, that less-than-market rates are no prerequisite...

  2. PENGARUH REPUTASI UNDERWRITER DAN REPUTASI AUDITOR TERHADAP UNDERPRICING

    Directory of Open Access Journals (Sweden)

    Nurfauziah Nurfauziah

    2015-11-01

    Full Text Available AbstractStock prices in the primary market are set by agreement between the issuer with the underwriter. Underwriters have more information to the request of the issuer's shares, so the information can be used to obtain optimal agreement with the issuer is to minimize the risk of having to buy shares that are not sold cheaply. With that reputation, share price offered in the primary market is lower than expected after stocks entered in the secondary market or did not happen underpricing. Auditors are also able to influence the level of underpricing. Auditor reputation of quality and professionalism demonstrated auditors audited the financial statements of the company. Using auditors of reputation will reduce the opportunities for issuers to cheat in presenting inaccurate information to the market. For this reason, it is needed; a study examines the effect of Underwriter Reputation and Auditor Reputation on Underpricng. The research was carried out on companies that experience underpricing at initial public offering in 2007 until 2009. Based on examining 42 companies that have been underpricing showing no effect of both underwriter and auditor reputation toward underpricing individually as well as all together.Keywords: IPO, underwriter, auditor, underpricing.AbstrakHarga saham di pasar perdana ditetapkan berdasarkan kesepakatan antara emiten dengan underwriter. Underwriter memiliki informasi yang lebih banyak terhadap permintaan saham-saham emiten, sehingga informasi tersebut dapat digunakan untuk memperoleh kesepakatan optimal dengan emiten yaitu dengan memperkecil risiko keharusan membeli saham yang tidak laku terjual dengan harga murah. Dengan reputasinya itu, harga saham yang ditawarkan di pasar perdana diharapkan tidak lebih rendah dibandingkan setelah saham masuk di pasar sekunder atau tidak terjadi underpricing. Auditor juga mampu mempengaruhi tingkat underpricing. Reputasi auditor menunjukkan kualitas dan profesionalisme auditor yang

  3. The underwriting process of liability insurance in South Africa

    Directory of Open Access Journals (Sweden)

    Anderson, S. E.

    2014-03-01

    Full Text Available Liability risks may embody far-reaching financial consequences for individuals, business enterprises and professional people. This paper focuses on the underwriting process which should be taken into consideration by short-term insurers when they are underwriting the main types of liability insurance, which include employer’s, householder’s, personal, product, professional and public liability insurance. The improvement of financial decision-making by short-term insurers when underwriting liability insurance represents the objective of this research. A study of secondary data was done to identify the existing literature, which formed the basis for compiling a questionnaire to obtain primary data. The top 10 short-term insurers which are the market leaders of liability insurance in South Africa and who received more than 85% of the annual gross written premiums for liability insurance in South Africa, represented the sample of the empirical study. This paper highlights the importance of the underwriting factors concerning liability insurance, how often the stipulations of insurance policies should be adjusted by the short-term insurers to account for the underwriting factors, as well as the problem areas which the underwriters may experience when they are underwriting liability insurance. Possible solutions to solve the problem areas were also addressed

  4. Structured settlement annuities, part 1: overview and the underwriting process.

    Science.gov (United States)

    Schmidt, C J; Singer, R B

    2000-01-01

    Structured settlement underwriting is the underwriting of medically impaired lives for the purchase of an annuity to fund the settlement. Other than risk assessment, structured settlement (SS) underwriting has little in common with traditional life insurance underwriting. Most noteworthy of these differences is the relative lack of actuarial data on which to base decisions about mortality and the necessity for prospective thinking about risk assessment. The purpose of this paper is to provide a foundation for understanding the structured settlement business and to contrast the underwriting of structured settlements with that of traditional life insurance. This is the first part of a two-part article on SS annuities. Part 2 deals with the mortality experience in SS annuitants and the life-table methodology used to calculate life expectancy for annuitants at increased mortality risk.

  5. 13 CFR 115.15 - Underwriting and servicing standards.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Underwriting and servicing standards. 115.15 Section 115.15 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SURETY BOND... underwriting and the Surety's principles and practices on unguaranteed bonds. The Principal must satisfy the...

  6. 12 CFR 528.2a - Nondiscriminatory appraisal and underwriting.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Nondiscriminatory appraisal and underwriting. 528.2a Section 528.2a Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY NONDISCRIMINATION REQUIREMENTS § 528.2a Nondiscriminatory appraisal and underwriting. (a) Appraisal. No savings...

  7. THE EFFECT OF MULTINATIONAL UNDERWRITING FIRMS ON INTELLECTUAL CAPITAL DISCLOCURE IN INDONESIAN IPO PROSPECTUSES

    Directory of Open Access Journals (Sweden)

    Dezie L. Warganegara

    2017-03-01

    Full Text Available The objective of this study was to investigate the effects of multinational underwriters on intellectual capitaldisclosure in Indonesian IPO prospectuses. Intellectual capital disclosure practices were driven by the adviceof underwriters. Multinational underwriters had a greater capacity to produce more relevant information so itreduced the information gap for IPO market participants. The information included IC disclosure practices inIPO prospectuses. This study found that the nationality of underwriting firms positively affected the extent ofintellectual capital disclosure in Indonesian IPO prospectuses. Exposure to IPOs in other countries and theability to combine dispersed knowledge across their international branches seemed to have a positive effect onmulti-national underwriting firms in as much as it led to a higher standard of disclosure of intellectual capitalthan that of local underwriting firms.

  8. Accruals quality, underwriter reputation, and corporate bond underpricing: Evidence from China

    Directory of Open Access Journals (Sweden)

    Si Xu

    2017-12-01

    Full Text Available This study examines the relationship between accruals quality and the underpricing of corporate bonds in China and how underwriter reputation affects this relationship. We find that (1 accruals quality is negatively associated with the magnitude of bond underpricing and (2 the impact of low accruals quality on underpricing is partially offset by hiring reputable underwriters. A path analysis shows that approximately 11% of the effect of accruals quality on underpricing is attributable to the indirect path through reputable underwriters, suggesting that accruals quality is more effective than reputable underwriters in lowering bond underpricing. These findings are significant for initial bond offerings, but not for secondary bond offerings. We also find that low accruals quality is associated with more restrictive non-price contract terms such as greater collateral requirements and stricter covenants.

  9. Predictive medical information and underwriting.

    Science.gov (United States)

    Dodge, John H

    2007-01-01

    Medical underwriting involves the application of actuarial science by analyzing medical information to predict the future risk of a claim. The objective is that individuals with like risk are treated in a like manner so that the premium paid is proportional to the risk of future claim.

  10. 17 CFR 250.4 - Exemption of certain brokers, dealers and underwriters.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Exemption of certain brokers... and General Exemptions § 250.4 Exemption of certain brokers, dealers and underwriters. (a) General exemption. Subject to the provision of § 250.6, any broker, dealer or underwriter, as defined in paragraph...

  11. 78 FR 46295 - Enterprise Underwriting Standards

    Science.gov (United States)

    2013-07-31

    ... 2590-AA53 Enterprise Underwriting Standards AGENCY: Federal Housing Finance Agency. ACTION: Proposed...), (together, the Enterprises) relating to mortgage assets affected by Property Assessed Clean Energy (PACE... that were encumbered by this retrofit lending program that created a priority ahead of the Enterprise...

  12. The Value of Bond Underwriter Relationships

    DEFF Research Database (Denmark)

    Daetz, Stine Louise; Dick-Nielsen, Jens; Nielsen, Mads Stenbo

    and lower underpricing. However, if the underwriter becomes distressed, this spills over to the issuer's credit risk, because it weakens the relationship and increases the risk of involuntary relationship termination. The credit risk spillover is more pronounced for risky, opaque issuers with high rollover...

  13. Prosedur Underwriting Bancassurance dan Asuransi Jiwa Syariah pada PT Asuransi Takaful Keluarga

    Directory of Open Access Journals (Sweden)

    Ella Patriana

    2015-10-01

    Full Text Available This study explains the comparative risk selection (of underwriting in bancassurance products and Islamic life insurance products at PT Family Takaful Insurance. The result revealed that the underwriting procedures of each product are different based on their characteristics. Full protection is designed as a simple of underwriting product only with age provisions and administrative requirements. Financing takaful products cover all financing from the banj. Thus, bank which does the insurance process will make these data as basic information about insurance customers. Since the bank is insured and apply risk selection process as risky selection process at most insurance companiesDOI: 10.15408/aiq.v4i1.2093

  14. Dealing with risk: Underwriting sovereign bond issues in London 1870-1914

    OpenAIRE

    Mikkelsen, Anders L.

    2014-01-01

    Using the records of several leading 19th century issuing houses, this paper analyses the transformation of underwriting practices in London's primary sovereign bond market from 1870 to 1914. It shows how underwriting risk developed from being a liability, which market intermediaries sought to avoid, to becoming a valuable financial commodity. The impetus for this development was increased competition in the loan business from the 1880s onwards, which weakened the negotiating position of issu...

  15. The shape of uncertainty: underwriting decisions in the face of catastrophic risk

    International Nuclear Information System (INIS)

    Keykhah, M.

    1998-01-01

    This paper will explore how insurance and re-insurance underwriters price catastrophe risk from natural perils. It will first describe the theoretical nature of pricing risk, and outline studies of underwriting that propose analyzing decision making from a more behavioral than rational choice perspective. The paper then argues that in order to provide the appropriate context for probability (which is the focus of the studies on decision making under uncertainty), it may be helpful to look at the nature of choice within a market and organizational context. Moreover, the nature of probability itself is explored with a review to construct a broader analysis. Finally, it will be argued that the causal framework of the underwriter, in addition to inductive reasoning, provides a shape to uncertainty. (author)

  16. PROSEDUR UNDERWRITING BANCASSURANCE DAN ASURANSI JIWA SYARIAH PADA PT. ASURANSI TAKÂFUL KELUARGA

    Directory of Open Access Journals (Sweden)

    Ella Patriana

    2016-02-01

    Full Text Available This study explains the comparative risk selection (of underwriting in bancassurance products and Islamic life insurance products at PT. Family Takaful Insurance. The result revealed that the underwriting procedures of each product are different based on their characteristics. Full protection is designed as a simple of underwriting product only with age provisions and administrative requirements. Financing takâful products cover all financing from the bank. Thus, bank which does the insurance process will make these data as basic information about insurance customers. Since the bank is insured, and apply risk selection process as risky selection process at most insurance companies.DOI: 10.15408/aiq.v4i1.2543

  17. How do underwriters value initial public offerings? An empirical analysis of the french IPO market

    NARCIS (Netherlands)

    P.G.J. Roosenboom (Peter)

    2007-01-01

    textabstractThis paper investigates how French underwriters value the stocks of companies they bring public. Underwriters often use several valuation methods to determine their fair value estimate of the initial public offering (IPO) firm's equity. We investigate five of these valuation methods:

  18. Medical Underwriting In Long-Term Care Insurance: Market Conditions Limit Options For Higher-Risk Consumers.

    Science.gov (United States)

    Cornell, Portia Y; Grabowski, David C; Cohen, Marc; Shi, Xiaomei; Stevenson, David G

    2016-08-01

    A key feature of private long-term care insurance is that medical underwriters screen out would-be buyers who have health conditions that portend near-term physical or cognitive disability. We applied common underwriting criteria based on data from two long-term care insurers to a nationally representative sample of individuals in the target age range (50-71 years) for long-term care insurance. The screening criteria put upper bounds on the current proportion of Americans who could gain coverage in the individual market without changes to medical underwriting practice. Specifically, our simulations show that in the target age range, approximately 30 percent of those whose wealth meets minimum industry standards for suitability for long-term care insurance would have their application for such insurance rejected at the underwriting stage. Among the general population-without considering financial suitability-we estimated that 40 percent would have their applications rejected. The predicted rejection rates are substantially higher than the rejection rates of about 20-25 percent of applicants in the actual market. In evaluating reforms for long-term care financing and their potential to increase private insurance rates, as well as to reduce financial pressure on public safety-net programs, policy makers need to consider the role of underwriting in the market for long-term care insurance. Project HOPE—The People-to-People Health Foundation, Inc.

  19. 12 CFR 211.605 - Permissible underwriting activities of foreign banks.

    Science.gov (United States)

    2010-01-01

    ... foreign company that directly underwrites, sells or distributes securities in the United States (emphasis... financial and managerial requirements in order to be able to engage in these activities in the United States...

  20. The Added Value of Medical Testing in Underwriting Life Insurance

    NARCIS (Netherlands)

    Bronsema, J.; Brouwer, S.; de Boer, M.R.; Groothoff, J.W.

    2015-01-01

    Background In present-day life-insurance medical underwriting practice the risk assessment starts with a standard health declaration (SHD). Indication for additional medical screening depends predominantly on age and amount of insured capital. From a medical perspective it is questionable whether

  1. 46 CFR 308.8 - War risk insurance underwriting agency agreement.

    Science.gov (United States)

    2010-10-01

    ... companies or groups of domestic insurance companies authorized to do a marine insurance business in any States of the United States, appointing such companies or groups of companies as Underwriting Agents to... performance, indemnification effective date, amendment and termination, and nondiscrimination. ...

  2. The Impact of Policy Incentives on Long-Term Care Insurance and Medicaid Costs: Does Underwriting Matter?

    Science.gov (United States)

    Cornell, Portia Y; Grabowski, David C

    2018-05-16

    To test whether underwriting modifies the effect of state-based incentives on individuals' purchase of long-term care insurance. Health and Retirement Study (HRS), 1996-2012. We estimated difference-in-difference regression models with an interaction of state policy indicators with individuals' probabilities of being approved for long-term care insurance. We imputed probabilities of underwriting approval for respondents in the HRS using a model developed with underwriting decisions from two U.S. insurance firms. We measured the elasticity response to long-term care insurance price using changes in simulated after-tax price as an instrumental variable for premium price. Tax incentives and Partnership programs increased insurance purchase by 3.62 percentage points and 1.8 percentage points, respectively, among those with the lowest risk (highest approval probability). Neither had any statistically significant effects among the highest risk individuals. We show that ignoring the effects of underwriting may lead to biased estimates of the potential state budget savings of long-term care insurance tax incentives. If the private market is to play a role in financing long-term care, policies need to address the underlying adverse selection problems. © Health Research and Educational Trust.

  3. 12 CFR 614.4150 - Lending policies and loan underwriting standards.

    Science.gov (United States)

    2010-01-01

    ... determining that an applicant has the operational, financial, and management resources necessary to repay the debt from cashflow (2) That are appropriate for each loan program and the institution's risk-bearing... loan underwriting standards. Under the policies of its board, each institution shall adopt written...

  4. 20 CFR 726.202 - Who may underwrite an operator's liability.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Who may underwrite an operator's liability. 726.202 Section 726.202 Employees' Benefits EMPLOYMENT STANDARDS ADMINISTRATION, DEPARTMENT OF LABOR FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969, AS AMENDED BLACK LUNG BENEFITS; REQUIREMENTS FOR COAL...

  5. 12 CFR 616.6300 - Leasing policies, procedures, and underwriting standards.

    Science.gov (United States)

    2010-01-01

    ... property and associated risks; (e) Property tax and sales tax reporting; (f) Title and ownership of leased... engaged in lease underwriting must adopt a written policy (or policies). Management, at the direction of the board, must develop procedures that reflect lease practices that control risk and comply with all...

  6. 26 CFR 1.823-6 - Determination of statutory underwriting income or loss.

    Science.gov (United States)

    2010-04-01

    ... TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Mutual Insurance Companies (other Than Life and Certain Marine Insurance Companies and Other Than Fire Or Flood Insurance Companies Which Operate on Basis... statutory underwriting income or loss for the taxable year, a mutual insurance company subject to the tax...

  7. The Added Value of Medical Testing in Underwriting Life Insurance.

    Directory of Open Access Journals (Sweden)

    Jan Bronsema

    Full Text Available In present-day life-insurance medical underwriting practice the risk assessment starts with a standard health declaration (SHD. Indication for additional medical screening depends predominantly on age and amount of insured capital. From a medical perspective it is questionable whether there is an association between the level of insured capital and medical risk in terms of mortality. The aim of the study is to examine the prognostic value of parameters from the health declaration and application form on extra mortality based on results from additional medical testing.A history register-based cohort study was conducted including about 15.000 application files accepted between 2007 and 2010. Blood pressure, lipids, cotinine and glucose levels were used as dependent variables in logistic regression models. Resampling validation was applied using 250 bootstrap samples to calculate area under the curves (AUC's. The AUC was used to discriminate between persons with and without at least 25% extra mortality.BMI and the overall assessment of the health declaration by an insurance physician or medical underwriter showed the strongest discrimination in multivariable analysis. Including all variables at minimum cut-off levels resulted in an AUC of 0.710 while by using a model with BMI, the assessment of the health declaration and gender, the AUC was 0.708. Including all variables at maximum cut-off levels lead to an AUC of 0.743 while a model with BMI, the assessment of the health declaration and age resulted in an AUC of 0.741.The outcome of this study shows that BMI and the overall assessment of the health declaration were the dominant variables to discriminate between applicants for life-insurance with and without at least 25 percent extra mortality. The variable insured capital set by insurers as factor for additional medical testing could not be established in this study population. The indication for additional medical testing at underwriting life

  8. 24 CFR 573.5 - Underwriting standards and availability of loan guarantee assistance.

    Science.gov (United States)

    2010-04-01

    ... acceptable financial risk under HUD's generally applicable loan underwriting standards based on the following: (1) The Borrower's ability to pay debt service; and (2) The value of the collateral assigned or... insufficient to make the guarantee an acceptable financial risk, or if the proposed interest rates or fees are...

  9. 7 CFR 4290.825 - Purchasing securities from an underwriter or other third party.

    Science.gov (United States)

    2010-01-01

    ... (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE RURAL BUSINESS INVESTMENT COMPANY (âRBICâ) PROGRAM Financing of Enterprises by RBICs Structuring Rbic Financing of Eligible Enterprises-Types of Financings § 4290.825 Purchasing securities from an underwriter or...

  10. 78 FR 75238 - Federal Housing Administration (FHA) Risk Management Initiatives: New Manual Underwriting...

    Science.gov (United States)

    2013-12-11

    ...-AJ07 Federal Housing Administration (FHA) Risk Management Initiatives: New Manual Underwriting... case numbers assigned on or after a date to be established by Mortgagee Letter following publication of... constrained. FHA played this role in the recent housing crisis, and the volume of FHA insurance increased...

  11. 75 FR 60171 - Proposed Information Collection (Credit Underwriting Standards and Procedures for Processing VA...

    Science.gov (United States)

    2010-09-29

    ... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-0521] Proposed Information Collection (Credit Underwriting Standards and Procedures for Processing VA Guaranteed Loans) Activity: Comment Request AGENCY... comment on the proposed collection of certain information by the agency. Under the Paperwork Reduction Act...

  12. 78 FR 60379 - Proposed Information Collection (Credit Underwriting Standards and Procedures for Processing VA...

    Science.gov (United States)

    2013-10-01

    ... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-0521] Proposed Information Collection (Credit Underwriting Standards and Procedures for Processing VA Guaranteed Loans) Activity: Comment Request AGENCY... comment on the proposed collection of certain information by the agency. Under the Paperwork Reduction Act...

  13. Capacity in the energy underwriting market - an overview

    International Nuclear Information System (INIS)

    Mulhall, L.

    1992-01-01

    It is important to clarify the different definitions of capacity, and in the insurance business this work has two distinct interpretations. The capacity of a Lloyd's syndicate is described by its ability to write premium income. Of more interest is the maximum ability and willingness of an underwriter, whether Lloyds's or Company, to commit itself to catastrophe loss policies. Or put more simply, what is the size of their line? It is this capacity for covering high value catastrophic exposure or Target Risks that will be discussed using the definition that capacity in this case is: ''The ability of insurance markets to cover any single maximum loss''. (Author)

  14. PROSEDUR UNDERWRITING PRODUK ASURANSI KESEHATAN KUMPULAN PADA PT. ASURANSI TAKAFUL KELUARGA

    Directory of Open Access Journals (Sweden)

    Miftahul Ulum

    2016-02-01

    Full Text Available Risiko adalah sesuatu yang dapat mengancam aktifitas perusahaan dan dapat menyebabkan gagalnya tujuan. Bagi perusahaan asuransi, risiko adalah ketika terjadi klaim dari peserta. Dengan adanya klaim maka perusahaan akan mengeluarkan sejumlah dana untuk pembayaran klaim tersebut sesuai dengan manfaat yang dijanjikan. Untuk itu, Proses underwriting harus dilakukan dengan cermat dan akurat agar tidak menimbulkan kerugian bagi perusahaan.DOI: 10.15408/aiq.v2i1.2476

  15. 75 FR 76082 - Agency Information Collection (Credit Underwriting Standards and Procedures for Processing VA...

    Science.gov (United States)

    2010-12-07

    ... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-0521] Agency Information Collection (Credit Underwriting Standards and Procedures for Processing VA Guaranteed Loans) Activity Under OMB Review AGENCY... information abstracted below to the Office of Management and Budget (OMB) for review and comment. The PRA...

  16. 78 FR 4159 - Notice of Proposed Information Collection: Comment Request; Direct Endorsement Underwriter/HUD...

    Science.gov (United States)

    2013-01-18

    ... lender's analysis of the appraisal report, identify areas of weakness for future training, and removing lenders that consistently exhibits careless underwriting and subsequently affect the risk to the... information collected is used by FHA to monitor the quality of the lender's analysis of the appraisal report...

  17. A Quantitative Approach to Credit Risk Management in the Underwriting Process for the Retail Portfolio

    Directory of Open Access Journals (Sweden)

    Andreea Costea

    2017-03-01

    Full Text Available The core of this paper encloses a mathematical approach of credit risk management, based on a scorecard model used in the bank’s underwriting process. The main purpose of this paper is to present how to develop, validate and apply a rating model in practice. Using 21568 loan applications provided by one of the largest banks from Romania, a scorecard is built for the underwriting purposes. The customer data used in the modeling is based on socio-demographic characteristics. The model is developed according to a set of statistical methods for parameter estimation. A real-life example of how to use such a model in the strategic decisions of a bank is presented. The cut-off score for the acceptance of the applications is calibrated to a potential risk appetite of the main four banks in Romania. From an evaluative perspective, this paper is compatible with an exploratory approach to quantitative research methodology.

  18. 17 CFR 270.27d-1 - Reserve requirements for principal underwriters and depositors to carry out the obligations to...

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Reserve requirements for....27d-1 Reserve requirements for principal underwriters and depositors to carry out the obligations to... reserve and as security for the purpose of assuring the refund of charges required by sections 27(d) and...

  19. Membrane Transporters for Bilirubin and Its Conjugates: A Systematic Review

    Directory of Open Access Journals (Sweden)

    Jovana Čvorović

    2017-12-01

    Full Text Available Background: Bilirubin is a highly-hydrophobic tetrapyrrole which binds to plasma albumin. It is conjugated in the liver to glucuronic acid, and the water-soluble glucuronides are excreted in urine and bile. The membrane transporters of bilirubin diglucuronide are well-known. Still undefined are however the transporters performing the uptake of bilirubin from the blood into the liver, a process known to be fast and not rate-limited. The biological importance of this process may be appraised by considering that in normal adults 200–300 mg of bilirubin are produced daily, as a result of the physiologic turnover of hemoglobin and cellular cytochromes. Nevertheless, research in this field has yielded controversial and contradicting results. We have undertaken a systematic review of the literature, believing in its utility to improve the existing knowledge and promote further advancements.Methods: We have sourced the PubMed database until 30 June 2017 by applying 5 sequential searches. Screening and eligibility criteria were applied to retain research articles reporting results obtained by using bilirubin molecules in membrane transport assays in vitro or by assessing serum bilirubin levels in in vivo experiments.Results: We have identified 311 articles, retaining 44, reporting data on experimental models having 6 incremental increases of complexity (isolated proteins, membrane vesicles, cells, organ fragments, in vivo rodents, and human studies, demonstrating the function of 19 membrane transporters, encoded by either SLCO or ABC genes. Three other bilirubin transporters have no gene, though one, i.e., bilitranslocase, is annotated in the Transporter Classification Database.Conclusions: This is the first review that has systematically examined the membrane transporters for bilirubin and its conjugates. Paradoxically, the remarkable advancements in the field of membrane transport of bilirubin have pointed to the elusive mechanism(s enabling

  20. A systematic review of interventions for promoting active transportation to school.

    Science.gov (United States)

    Chillón, Palma; Evenson, Kelly R; Vaughn, Amber; Ward, Dianne S

    2011-02-14

    Active transportation to school is an important contributor to the total physical activity of children and adolescents. However, active school travel has declined over time, and interventions are needed to reverse this trend. The purpose of this paper is to review intervention studies related to active school transportation to guide future intervention research. A systematic review was conducted to identify intervention studies of active transportation to school published in the scientific literature through January 2010. Five electronic databases and a manual search were conducted. Detailed information was extracted, including a quantitative assessment comparing the effect sizes, and a qualitative assessment using an established evaluation tool. We identified 14 interventions that focused on active transportation to school. These interventions mainly focused on primary school children in the United States, Australia, and the United Kingdom. Almost all the interventions used quasi-experimental designs (10/14), and most of the interventions reported a small effect size on active transportation (6/14). More research with higher quality study designs and measures should be conducted to further evaluate interventions and to determine the most successful strategies for increasing active transportation to school. © 2011 Chillón P et al; licensee BioMed Central Ltd.

  1. Scaling analysis in modeling transport and reaction processes a systematic approach to model building and the art of approximation

    CERN Document Server

    Krantz, William B

    2007-01-01

    This book is unique as the first effort to expound on the subject of systematic scaling analysis. Not written for a specific discipline, the book targets any reader interested in transport phenomena and reaction processes. The book is logically divided into chapters on the use of systematic scaling analysis in fluid dynamics, heat transfer, mass transfer, and reaction processes. An integrating chapter is included that considers more complex problems involving combined transport phenomena. Each chapter includes several problems that are explained in considerable detail. These are followed by several worked examples for which the general outline for the scaling is given. Each chapter also includes many practice problems. This book is based on recognizing the value of systematic scaling analysis as a pedagogical method for teaching transport and reaction processes and as a research tool for developing and solving models and in designing experiments. Thus, the book can serve as both a textbook and a reference boo...

  2. A Quantitative and Systematic Methodology to Investigate Energy Consumption Issues in Multimodal Intercity Transportation Systems

    Directory of Open Access Journals (Sweden)

    Lili Du

    2015-09-01

    Full Text Available Energy issues in transportation systems have garnered increasing attention recently. This study proposes a systematic methodology for policy-makers to minimize energy consumption in multimodal intercity transportation systems considering suppliers’ operational constraints and travelers’ mobility requirements. A bi-level optimization model is developed for this purpose and considers the air, rail, private auto, and transit modes. The upper-level model is a mixed integer nonlinear program aiming to minimize energy consumption subject to transportation suppliers’ operational constraints and traffic demand distribution to paths resulting from the lower-level model. The lower-level model is a linear program seeking to maximize the trip utilities of travelers. The interactions between the multimodal transportation suppliers and intercity traffic demand are considered under the goal of minimizing system energy consumption. The proposed bi-level mixed integer model is relaxed and transformed into a mathematical program with complementarity constraints, and solved using a customized branch-and-bound algorithm. Numerical experiments, conducted using multimodal travel options between Lafayette, Indiana and Washington, D.C. reiterate that shifting traffic demand from private cars to the transit and rail modes significantly reduce energy consumption. Moreover, the proposed methodology provides tools to quantitatively analyze system energy consumption and traffic demand distribution among transportation modes under specific policy instruments. The results illustrate the need to systematically incorporate the interactions among traveler preferences, network structure, and supplier operational schemes to provide policy-makers insights for developing traffic demand shift mechanisms to minimize system energy consumption. Hence, the proposed methodology provide policy-makers the capability to analyze energy consumption in the transportation sector by a

  3. Cross-continental comparison of the association between the physical environment and active transportation in children: a systematic review.

    Science.gov (United States)

    D'Haese, Sara; Vanwolleghem, Griet; Hinckson, Erica; De Bourdeaudhuij, Ilse; Deforche, Benedicte; Van Dyck, Delfien; Cardon, Greet

    2015-11-26

    The purpose of this systematic review was to determine the relationship between a wide range of physical environmental characteristics and different contexts of active transportation in 6- to 12-year-old children across different continents. A systematic search was conducted in six databases (Pubmed, Web of Science, Cinahl, SportDiscus, TRIS and Cochrane) resulting in 65 papers, eligible for inclusion. The investigated physical environmental variables were grouped into six categories: walkability, accessibility, walk/cycle facilities, aesthetics, safety, recreation facilities. The majority of the studies were conducted in North America (n = 35), Europe (n = 17) and Australia (n = 11). Active transportation to school (walking or cycling) was positively associated with walkability. Walking to school was positively associated with walkability, density and accessibility. Evidence for a possible association was found for traffic safety and all forms of active transportation to school. No convincing evidence was found for associations between the physical environment and active transportation during leisure. General safety and traffic safety were associated with active transportation to school in North America and Australia but not associated with active transportation to school in Europe. The physical environment was mainly associated with active transportation to school. Continent specific associations were found, indicating that safety measures were most important in relation to active commuting to school in North America and Australia. There is a need for longitudinal studies and studies conducted in Asia, Africa and South-America and studies focusing specifically on active transportation during leisure.

  4. The roles of transportation and transportation hubs in the propagation of influenza and coronaviruses: a systematic review.

    Science.gov (United States)

    Browne, Annie; Ahmad, Sacha St-Onge; Beck, Charles R; Nguyen-Van-Tam, Jonathan S

    2016-01-01

    Respiratory viruses spread in humans across wide geographical areas in short periods of time, resulting in high levels of morbidity and mortality. We undertook a systematic review to assess the evidence that air, ground and sea mass transportation systems or hubs are associated with propagating influenza and coronaviruses. Healthcare databases and sources of grey literature were searched using pre-defined criteria between April and June 2014. Two reviewers screened all identified records against the protocol, undertook risk of bias assessments and extracted data using a piloted form. Results were analysed using a narrative synthesis. Forty-one studies met the eligibility criteria. Risk of bias was high in the observational studies, moderate to high in the reviews and moderate to low in the modelling studies. In-flight influenza transmission was identified substantively on five flights with up to four confirmed and six suspected secondary cases per affected flight. Five studies highlighted the role of air travel in accelerating influenza spread to new areas. Influenza outbreaks aboard cruise ships affect 2-7% of passengers. Influenza transmission events have been observed aboard ground transport vehicles. High heterogeneity between studies and the inability to exclude other sources of infection means that the risk of influenza transmission from an index case to other passengers cannot be accurately quantified. A paucity of evidence was identified describing severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus transmission events associated with transportation systems or hubs. Air transportation appears important in accelerating and amplifying influenza propagation. Transmission occurs aboard aeroplanes, at the destination and possibly at airports. Control measures to prevent influenza transmission on cruise ships are needed to reduce morbidity and mortality. There is no recent evidence of sea transport accelerating influenza

  5. Objectively measured walkability and active transport and weight-related outcomes in adults: a systematic review.

    Science.gov (United States)

    Grasser, Gerlinde; Van Dyck, Delfien; Titze, Sylvia; Stronegger, Willibald

    2013-08-01

    The aim of this study was to investigate which GIS-based measures of walkability (density, land-use mix, connectivity and walkability indexes) in urban and suburban neighbourhoods are used in research and which of them are consistently associated with walking and cycling for transport, overall active transportation and weight-related measures in adults. A systematic review of English publications using PubMed, Science Direct, Active Living Research Literature Database, the Transportation Research Information Service and reference lists was conducted. The search terms utilised were synonyms for GIS in combination with synonyms for the outcomes. Thirty-four publications based on 19 different studies were eligible. Walkability measures such as gross population density, intersection density and walkability indexes most consistently correlated with measures of physical activity for transport. Results on weight-related measures were inconsistent. More research is needed to determine whether walkability is an appropriate measure for predicting weight-related measures and overall active transportation. As most of the consistent correlates, gross population density, intersection density and the walkability indexes have the potential to be used in planning and monitoring.

  6. Levels of ambient air pollution according to mode of transport: a systematic review.

    Science.gov (United States)

    Cepeda, Magda; Schoufour, Josje; Freak-Poli, Rosanne; Koolhaas, Chantal M; Dhana, Klodian; Bramer, Wichor M; Franco, Oscar H

    2017-01-01

    Controversy exists about the differences in air pollution exposure and inhalation dose between mode of transport. We aimed to review air pollution exposure and inhaled dose according to mode of transport and pollutant and their effect in terms of years of life expectancy (YLE). In this systematic review, we searched ten online databases from inception to April 13, 2016, without language or temporal restrictions, for cohort, cross-sectional, and experimental studies that compared exposure to carbon monoxide, black carbon, nitrogen dioxide, and fine and coarse particles in active commuters (pedestrian or cyclist) and commuters using motorised transport (car, motorcycle, bus, or massive motorised transport [MMT-ie, train, subway, or metro]). We excluded studies that measured air pollution exposure exclusively with biomarkers or on the basis of simulated data, reviews, comments, consensuses, editorials, guidelines, in-vitro studies, meta-analyses, ecological studies, and protocols. We extracted average exposure and commuting time per mode of transport and pollutant to calculate inhaled doses. We calculated exposure and inhaled dose ratios using active commuters as the reference and summarised them with medians and IQRs. We also calculated differences in YLE due to fine particle inhaled dose and physical activity. We identified 4037 studies, of which 39 were included in the systematic review. Overall, car commuters had higher exposure to all pollutants than did active commuters in 30 (71%) of 42 comparisons (median ratio 1·22 [IQR 0·90-1·76]), followed by those who commuted by bus in 57 (52%) of 109 (1·0 [0·79-1·41]), by motorcycle in 16 (50%) of 32 (0·99 [0·86-1·38]), by a car with controlled ventilation settings in 39 (45%) of 86 (0·95 [0·66-1·54]), and by MMT in 21 (38%) of 55 (0·67 [0·49-1·13]). Overall, active commuters had higher inhalation doses than did commuters using motorised transport (median ratio car with controlled ventilation settings 0

  7. Modelling freight transport

    NARCIS (Netherlands)

    Tavasszy, L.A.; Jong, G. de

    2014-01-01

    Freight Transport Modelling is a unique new reference book that provides insight into the state-of-the-art of freight modelling. Focusing on models used to support public transport policy analysis, Freight Transport Modelling systematically introduces the latest freight transport modelling

  8. A systematic review of factors affecting driving and public transportation among youth and young adults with acquired brain injury.

    Science.gov (United States)

    Lindsay, Sally; Stoica, Andrei

    2017-01-01

    Although many people with an acquired brain injury (ABI) encounter difficulties with executive functioning and memory which could negatively affect driving, few people are assessed for fitness to drive after injury. The purpose of this systematic review was to synthesize the literature on factors affecting driving and public transportation among youth and young adults with ABI, post injury. Seven databases were systematically searched for articles from 1980 to 2016. Studies were screened independently by two researchers who performed the data extraction. Study quality was appraised using the Standard Quality Assessment Criteria (Kmet) for evaluating primary research from a variety of fields. Of the 6577 studies identified in the search, 25 met the inclusion criteria, which involved 1527 participants with ABI (mean age = 25.1) across eight countries. Six studies focused on driving assessment and fitness to drive, ten on driving performance or risk of accidents and nine studies explored issues related to accessing or navigating public transportation. Quality assessment of the included studies ranged from 0.60 to 0.95. Our findings highlight several gaps in clinical practice and research along with a critical need for enhanced fitness to drive assessments and transportation-related training for young people with ABI.

  9. Colorado River sediment transport: 2. Systematic bed‐elevation and grain‐size effects of sand supply limitation

    Science.gov (United States)

    Topping, David J.; Rubin, David M.; Nelson, Jonathan M.; Kinzel, Paul J.; Corson, Ingrid C.

    2000-01-01

    The Colorado River in Marble and Grand Canyons displays evidence of annual supply limitation with respect to sand both prior to [Topping et al, this issue] and after the closure of Glen Canyon Dam in 1963. Systematic changes in bed elevation and systematic coupled changes in suspended‐sand concentration and grain size result from this supply limitation. During floods, sand supply limitation either causes or modifies a lag between the time of maximum discharge and the time of either maximum or minimum (depending on reach geometry) bed elevation. If, at a cross section where the bed aggrades with increasing flow, the maximum bed elevation is observed to lead the peak or the receding limb of a flood, then this observed response of the bed is due to sand supply limitation. Sand supply limitation also leads to the systematic evolution of sand grain size (both on the bed and in suspension) in the Colorado River. Sand input during a tributary flood travels down the Colorado River as an elongating sediment wave, with the finest sizes (because of their lower settling velocities) traveling the fastest. As the fine front of a sediment wave arrives at a given location, the bed fines and suspended‐sand concentrations increase in response to the enhanced upstream supply of finer sand. Then, as the front of the sediment wave passes that location, the bed is winnowed and suspended‐sand concentrations decrease in response to the depletion of the upstream supply of finer sand. The grain‐size effects of depletion of the upstream sand supply are most obvious during periods of higher dam releases (e.g., the 1996 flood experiment and the 1997 test flow). Because of substantial changes in the grain‐size distribution of the bed, stable relationships between the discharge of water and sand‐transport rates (i.e., stable sand rating curves) are precluded. Sand budgets in a supply‐limited river like the Colorado River can only be constructed through inclusion of the physical

  10. Gender differences in walking (for leisure, transport and in total) across adult life: a systematic review.

    Science.gov (United States)

    Pollard, Tessa M; Wagnild, Janelle M

    2017-04-20

    The aim of this systematic review was to examine gender differences in walking for leisure, transport and in total in adults living in high-income countries, and to assess whether gender differences in walking practices change across the life-course. A systematic literature search was conducted of publications dated 1995 to 2015. Papers providing quantitative data on participation in walking of both men and women aged at least 18 years in a high-income country were screened for the quality of the data on gender differences in walking. Data were extracted and results were synthesised using forest plots and narrative summary. Thirty-six studies were included in the review: 18 reported on walking for leisure, 16 on walking for transport (in total, or for particular purposes), and 14 on total walking. Most (33) studies provided data comparing the proportion of men and women who walked (at all or for a minimum duration) over a defined period, usually one week. There was consistent evidence that more women than men walk for leisure, although effect sizes were small. However, this effect varies by age: more younger women than younger men walk for leisure, but the gender difference diminishes with age and appears to reverse in the oldest age groups. Taking all ages together, there was no consistent gender difference in walking for transport or in total walking, although the small number of studies reporting on walking to undertake errands suggested that more women than men walk for this purpose. While there is little evidence that levels of total walking consistently vary by gender, our findings suggest that there are consistent gender differences in participation in walking for some purposes, including for leisure, and that there are gender differences in the impact of age on walking. We conclude that more research is needed to improve our understanding of how walking fits into the lives of women and men across the life-course, especially in relation to gender

  11. Advanced transport modeling of toroidal plasmas with transport barriers

    International Nuclear Information System (INIS)

    Fukuyama, A.; Murakami, S.; Honda, M.; Izumi, Y.; Yagi, M.; Nakajima, N.; Nakamura, Y.; Ozeki, T.

    2005-01-01

    Transport modeling of toroidal plasmas is one of the most important issue to predict time evolution of burning plasmas and to develop control schemes in reactor plasmas. In order to describe the plasma rotation and rapid transition self-consistently, we have developed an advanced scheme of transport modeling based on dynamical transport equation and applied it to the analysis of transport barrier formation. First we propose a new transport model and examine its behavior by the use of conventional diffusive transport equation. This model includes the electrostatic toroidal ITG mode and the electromagnetic ballooning mode and successfully describes the formation of internal transport barriers. Then the dynamical transport equation is introduced to describe the plasma rotation and the radial electric field self-consistently. The formation of edge transport barriers is systematically studied and compared with experimental observations. The possibility of kinetic transport modeling in velocity space is also examined. Finally the modular structure of integrated modeling code for tokamaks and helical systems is discussed. (author)

  12. Association of manual or engine-driven glide path preparation with canal centring and apical transportation: a systematic review.

    Science.gov (United States)

    Hartmann, R C; Peters, O A; de Figueiredo, J A P; Rossi-Fedele, G

    2018-04-28

    The role and effect of glide path preparation in root canal treatment remain controversial. This systematic review aims to compare apical transportation and canal centring of different glide path preparation techniques, with or without subsequent engine-driven root canal preparation. A database search in PubMed, PubMed Central, Embase, Scopus, EBSCO Dentistry & Oral Sciences Source and Virtual Health Library was conducted, using appropriate key words to identify the effect of glide path preparation (or its absence) on apical transportation and canal centring. An assessment for the risk of bias in included studies was carried out. Amongst 2146 studies, 18 satisfied the inclusion criteria. Nine studies assessed glide path preparation per se, comparing apical transportation and canal centring of rotary systems and/or manual files; eleven further investigations examined the efficacy of the glide path prior to final canal preparation with different engine-driven systems. Risk of bias and other study design features with potential influence on study outcomes and clinical implications were assessed. Based on the available evidence, and within the limitation of the studies included, preparation of a glide path using rotary sequences performs similarly (in most of the component studies) or significantly better than manual preparation when assessing apical transportation or canal centring. When compared to the absence of a glide path, canal shaping following glide path preparation was of similar, or significantly better quality, in regard to apical transportation or canal centring. © 2018 International Endodontic Journal. Published by John Wiley & Sons Ltd.

  13. Contributions of systematic tile drainage to watershed-scale phosphorus transport.

    Science.gov (United States)

    King, Kevin W; Williams, Mark R; Fausey, Norman R

    2015-03-01

    Phosphorus (P) transport from agricultural fields continues to be a focal point for addressing harmful algal blooms and nuisance algae in freshwater systems throughout the world. In humid, poorly drained regions, attention has turned to P delivery through subsurface tile drainage. However, research on the contributions of tile drainage to watershed-scale P losses is limited. The objective of this study was to evaluate long-term P movement through tile drainage and its manifestation at the watershed outlet. Discharge data and associated P concentrations were collected for 8 yr (2005-2012) from six tile drains and from the watershed outlet of a headwater watershed within the Upper Big Walnut Creek watershed in central Ohio. Results showed that tile drainage accounted for 47% of the discharge, 48% of the dissolved P, and 40% of the total P exported from the watershed. Average annual total P loss from the watershed was 0.98 kg ha, and annual total P loss from the six tile drains was 0.48 kg ha. Phosphorus loads in tile and watershed discharge tended to be greater in the winter, spring, and fall, whereas P concentrations were greatest in the summer. Over the 8-yr study, P transported in tile drains represented 90% of all measured concentrations exceeded recommended levels (0.03 mg L) for minimizing harmful algal blooms and nuisance algae. Thus, the results of this study show that in systematically tile-drained headwater watersheds, the amount of P delivered to surface waters via tile drains cannot be dismissed. Given the amount of P loss relative to typical application rates, development and implementation of best management practices (BMPs) must jointly consider economic and environmental benefits. Specifically, implementation of BMPs should focus on late fall, winter, and early spring seasons when most P loading occurs. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  14. Systematic Experimental and Computational Investigation of Ion Transport in Novel Polyether Electrolytes

    Science.gov (United States)

    Pesko, Danielle; Webb, Michael; Jung, Yukyung; Zheng, Qi; Miller, Thomas, III; Coates, Geoffrey; Balsara, Nitash

    Polyethers, such as poly(ethylene oxide) (PEO), are considered to be the most promising polymer electrolyte materials due to their high ionic conductivity and electrochemical stability, both essential for battery applications. To gain a fundamental understanding of the transport properties of polyether systems, we design a systematic set of linear PEO-like polymers to explore the effect of adding carbon spacers to the backbone of the chain. Ac impedance spectroscopy is employed to measure the ionic conductivity of polyether/lithium salt electrolytes; the results elucidate tradeoffs between lowering the glass transition temperature and diluting the polar groups on the polymer chain. Molecular-level insight is provided by molecular dynamics simulations of the polyether electrolytes. We define the useful and intuitive metric of ``connectivity'', a parameter calculated from simulations which describes the physical arrangements of solvation sites in a polymer melt. Direct comparison of experiment and theory allows us to determine the relationship between connectivity and conductivity. The comparison provides insight regarding the factors that control conductivity, and highlights considerations that must be taken when designing new ion-conducting polymers.

  15. Active Transport to School and Children's Body Weight: A Systematic Review

    Directory of Open Access Journals (Sweden)

    Houshmand E. Masoumi

    2017-04-01

    Full Text Available Because of decreasing physical activity of children, they are becoming more obese. Moreover, commuting to school has become more passive during the past decades. The objective was to update the previous systematic reviews by narrowing down the topic to body mass index of children (3-12 years as a representative of body composition.  Applying search terms such as active transport to school, body mass index, childhood obesity, and so on in four online databases: PubMed, ScienceDirect, WorldCat, and Google Scholar. Peer-reviewed English journal papers published between 2005 and 2015 presenting empirical quantitative studies were eligible studies to be reviewed. 310 journal papers were screened, 27 of which were reviewed by studying the full text. The final 13 papers were limited to those that focused only on active commuting to school and body mass index of children and adolescents. Out of 13 final studies, 3 found conclusive associations, three indicate partial associations in subgroups or societal or geographical limitations, and seven show no correlations. The existing literature are still inconsistent, so this study suggests conducting surveys with larger samples on less-studied contexts and applying more complex statistical methods for adjusting some of the variables. It is also argued that this topic can be culturally and contextually specific.

  16. Corruption, Political Connections, and Municipal Finance

    OpenAIRE

    Alexander W. Butler; Larry Fauver; Sandra Mortal

    2009-01-01

    We show that state corruption and political connections have strong effects on municipal bond sales and underwriting. Higher state corruption is associated with greater credit risk and higher bond yields. Corrupt states can eliminate the corruption yield penalty by purchasing credit enhancements. Underwriting fees were significantly higher during an era when underwriters made political contributions to win underwriting business. This pay-to-play underwriting fee premium exists only for negoti...

  17. Systematic literature review of built environment effects on physical activity and active transport - an update and new findings on health equity.

    Science.gov (United States)

    Smith, Melody; Hosking, Jamie; Woodward, Alistair; Witten, Karen; MacMillan, Alexandra; Field, Adrian; Baas, Peter; Mackie, Hamish

    2017-11-16

    Evidence is mounting to suggest a causal relationship between the built environment and people's physical activity behaviours, particularly active transport. The evidence base has been hindered to date by restricted consideration of cost and economic factors associated with built environment interventions, investigation of socioeconomic or ethnic differences in intervention effects, and an inability to isolate the effect of the built environment from other intervention types. The aims of this systematic review were to identify which environmental interventions increase physical activity in residents at the local level, and to build on the evidence base by considering intervention cost, and the differential effects of interventions by ethnicity and socioeconomic status. A systematic database search was conducted in June 2015. Articles were eligible if they reported a quantitative empirical study (natural experiment or a prospective, retrospective, experimental, or longitudinal research) investigating the relationship between objectively measured built environment feature(s) and physical activity and/or travel behaviours in children or adults. Quality assessment was conducted and data on intervention cost and whether the effect of the built environment differed by ethnicity or socioeconomic status were extracted. Twenty-eight studies were included in the review. Findings showed a positive effect of walkability components, provision of quality parks and playgrounds, and installation of or improvements in active transport infrastructure on active transport, physical activity, and visits or use of settings. There was some indication that infrastructure improvements may predominantly benefit socioeconomically advantaged groups. Studies were commonly limited by selection bias and insufficient controlling for confounders. Heterogeneity in study design and reporting limited comparability across studies or any clear conclusions to be made regarding intervention cost

  18. Transport policies related to climate change mitigation

    DEFF Research Database (Denmark)

    Mathiesen, Brian Vad; Kappel, Jannik

    and their results are introduced as well. To provide an overview of current trends, related scientific projects and other analyses on climate change mitigation and transport are given in the report. The references used in this report can also serve as a source of data and inspiration for the reader. This report......This report presents the Danish national policies on reducing the emissions of greenhouse gasses and reducing Denmark’s dependency on fossil fuels in the transport sector, as well as some of the results of the policies. Systematic focus on efficient transport and climate mitigation started in 2008...... challenges for the transport sectors, which has not yet been systematically analysed from any Governmental body. In this report we list projects which have done so. The first chapter describes policies and initiatives of international relevance within climate mitigation. The following chapters explain...

  19. Work-related posttraumatic stress disorder (PTSD) and other emotional diseases as consequence of traumatic events in public transportation: a systematic review.

    Science.gov (United States)

    Clarner, Annika; Graessel, Elmar; Scholz, Johanna; Niedermeier, Alexander; Uter, Wolfgang; Drexler, Hans

    2015-07-01

    Drivers in public transportation are at risk of experiencing potential traumatic events such as accidents involving persons, collisions, or suicides. In this context, the question arises to what extent psychological traumatization and posttraumatic diseases occur. The aim of this systematic review was to describe the frequency and nature of work-related posttraumatic disorders, to analyze risk and prognostic factors after potentially traumatic events (accidents resulting in damage to property and/or in injury or death), and address sick leave after such events in the realm of public transportation, based on the available literature. Systematic review based on four databases (PubMed, PSYNDEX/MEDLINE, ScienceDirect, PILOTS) between 1980 and June 2013. We identified seven studies (four longitudinal, three cross-sectional) that examine employees after person under train (PUT) events. PTSD prevalences varied broadly between 0.7 and 17 %. The same applies to dysthymia/neurotic depression (1-26 %). However, similarly low prevalences of major depression (1.3-2.8 %) and panic disorder (0.5-1.3 %) have been observed. Risk factors of PTSD comprised individual, work-related, event-related, and prognostic aspects. Following the traumatic event, a total of 69-81 % of the drivers were absent, and if sick leave occurs, this was on average 3-19 days. It became evident that drivers in public transportation run a high risk of sick leave. It was also striking that despite the immense impact of PUT and high number of suicides, only an infinitesimal number of studies exists. Due to various differences (period of follow-up, instrument of measurement and study period), it turned out that the comparability of the results of the studies is limited. For various reasons, further research is urgently needed, as from an occupational health point of view the issue of posttraumatic diseases and implications for fitness for service should be addressed.

  20. 76 FR 77865 - Self-Regulatory Organizations; Municipal Securities Rulemaking Board; Order Instituting...

    Science.gov (United States)

    2011-12-14

    ... instead require underwriters to have actual knowledge whether an official has the power to bind the issuer... bind the issuer by contract with the underwriter and that, to the knowledge of the underwriter, is not... knowledge to perform the proposed underwriting as of the time the proposal is submitted and must not contain...

  1. Safety as a management concept in the air transport sector: A systematic literature review

    Directory of Open Access Journals (Sweden)

    Fernando Campa-Planas

    2017-01-01

    Full Text Available Purpose: The main purpose of the present study is to conduct a literature review of the contribution made by safety in air transport, based on the existing international academic literature in the field of the social sciences. It primarily attempts to examine and verify the relationship between safety-related concepts (co-occurrence, the link between the different authors (co-authorship and the corresponding citations (co-citations. Methodology: To achieve the established objectives, a systematic literature review (SLR has been conducted using the Scopus database between the years 1990 and 2016, identifying international academic papers related to the research topic of the present study. Findings: It has been verified, on the one hand, that safety in the air transport sector is a field of growing interest, as the number of papers has increased considerably in recent years, thus demonstrating the importance that this topic has acquired over time. On the other hand, however, it must be mentioned that the total quantity of papers related to the topic is low in terms of absolute numbers. The results of the co-occurrence analysis show that the most important aspect of safety is safety management, while the strongest link is between safety management and aircraft accidents, a fact that is foreseeable a priori.  Originality/value: The approach used allows a better view of the academic contribution made in relation to safety; this serves as the link among the different elements of the concept studied, and it demonstrates the growing interest in this area.

  2. Improving road transport operations through lean thinking: A case study

    OpenAIRE

    Villarreal, B.; Garza-Reyes, J. A.; Kumar, V.; Lim, M. K.

    2017-01-01

    Traditionally, logistics and transportation problems have been addressed through mathematical modelling, operations research, and simulation methods. This paper documents a case study where the road transport operations of a leading Mexican brewery organisation have been improved through lean thinking and waste reduction. Two lean-based principles and tools were combined; the Seven Transportation Extended Wastes (STEWs) and Transportation Value Stream Mapping (TVSM), and three systematic step...

  3. GIS measured environmental correlates of active school transport: A systematic review of 14 studies

    Directory of Open Access Journals (Sweden)

    Faulkner Guy

    2011-05-01

    Full Text Available Abstract Background Emerging frameworks to examine active school transportation (AST commonly emphasize the built environment (BE as having an influence on travel mode decisions. Objective measures of BE attributes have been recommended for advancing knowledge about the influence of the BE on school travel mode choice. An updated systematic review on the relationships between GIS-measured BE attributes and AST is required to inform future research in this area. The objectives of this review are: i to examine and summarize the relationships between objectively measured BE features and AST in children and adolescents and ii to critically discuss GIS methodologies used in this context. Methods Six electronic databases, and websites were systematically searched, and reference lists were searched and screened to identify studies examining AST in students aged five to 18 and reporting GIS as an environmental measurement tool. Fourteen cross-sectional studies were identified. The analyses were classified in terms of density, diversity, and design and further differentiated by the measures used or environmental condition examined. Results Only distance was consistently found to be negatively associated with AST. Consistent findings of positive or negative associations were not found for land use mix, residential density, and intersection density. Potential modifiers of any relationship between these attributes and AST included age, school travel mode, route direction (e.g., to/from school, and trip-end (home or school. Methodological limitations included inconsistencies in geocoding, selection of study sites, buffer methods and the shape of zones (Modifiable Areal Unit Problem [MAUP], the quality of road and pedestrian infrastructure data, and school route estimation. Conclusions The inconsistent use of spatial concepts limits the ability to draw conclusions about the relationship between objectively measured environmental attributes and AST. Future

  4. Human transporter database: comprehensive knowledge and discovery tools in the human transporter genes.

    Directory of Open Access Journals (Sweden)

    Adam Y Ye

    Full Text Available Transporters are essential in homeostatic exchange of endogenous and exogenous substances at the systematic, organic, cellular, and subcellular levels. Gene mutations of transporters are often related to pharmacogenetics traits. Recent developments in high throughput technologies on genomics, transcriptomics and proteomics allow in depth studies of transporter genes in normal cellular processes and diverse disease conditions. The flood of high throughput data have resulted in urgent need for an updated knowledgebase with curated, organized, and annotated human transporters in an easily accessible way. Using a pipeline with the combination of automated keywords query, sequence similarity search and manual curation on transporters, we collected 1,555 human non-redundant transporter genes to develop the Human Transporter Database (HTD (http://htd.cbi.pku.edu.cn. Based on the extensive annotations, global properties of the transporter genes were illustrated, such as expression patterns and polymorphisms in relationships with their ligands. We noted that the human transporters were enriched in many fundamental biological processes such as oxidative phosphorylation and cardiac muscle contraction, and significantly associated with Mendelian and complex diseases such as epilepsy and sudden infant death syndrome. Overall, HTD provides a well-organized interface to facilitate research communities to search detailed molecular and genetic information of transporters for development of personalized medicine.

  5. Valuing and pricing IPOs

    NARCIS (Netherlands)

    P.G.J. Roosenboom (Peter)

    2012-01-01

    textabstractThis paper investigates how underwriters set the IPO firm’s fair value, an ex-ante estimate of the market value, using a unique dataset of 228 reports from French underwriters. These reports are issued before the IPO shares start trading on the stock market and detail how underwriters

  6. 12 CFR 563b.200 - What actions may OTS take on my application?

    Science.gov (United States)

    2010-01-01

    ... appraiser may serve as an underwriter or selling agent, if you ensure that the appraiser is separate from the underwriter or selling agent affiliate and the underwriter or selling agent affiliate does not... convenience and needs of your communities after the conversion. (1) Based on this review, OTS may approve your...

  7. Institutional issues affecting transportation of nuclear materials

    International Nuclear Information System (INIS)

    Reese, R.T.; Luna, R.E.

    1980-01-01

    The institutional issues affecting transportation of nuclear materials in the United States represent significant barriers to meeting future needs in the transport of radioactive waste materials to their ultimate repository. While technological problems which must be overcome to perform such movements seem to be within the state-of-the-art, the timely resolution of these institutional issues seems less assured. However, the definition of these issues, as attempted in this paper, together with systematic analysis of cause and possible solutions are the essential elements of the Transportation Technology Center's Institutional Issues Program

  8. Verification of consumers' experiences and perceptions of genetic discrimination and its impact on utilization of genetic testing.

    Science.gov (United States)

    Barlow-Stewart, Kristine; Taylor, Sandra D; Treloar, Susan A; Stranger, Mark; Otlowski, Margaret

    2009-03-01

    To undertake a systematic process of verification of consumer accounts of alleged genetic discrimination. Verification of incidents reported in life insurance and other contexts that met the criteria of genetic discrimination, and the impact of fear of such treatment, was determined, with consent, through interview, document analysis and where appropriate, direct contact with the third party involved. The process comprised obtaining evidence that the alleged incident was accurately reported and determining whether the decision or action seemed to be justifiable and/or ethical. Reported incidents of genetic discrimination were verified in life insurance access, underwriting and coercion (9), applications for worker's compensation (1) and early release from prison (1) and in two cases of fear of discrimination impacting on access to genetic testing. Relevant conditions were inherited cancer susceptibility (8), Huntington disease (3), hereditary hemochromatosis (1), and polycystic kidney disease (1). In two cases, the reversal of an adverse underwriting decision to standard rate after intervention with insurers by genetics health professionals was verified. The mismatch between consumer and third party accounts in three life insurance incidents involved miscommunication or lack of information provision by financial advisers. These first cases of verified genetic discrimination make it essential for policies and guidelines to be developed and implemented to ensure appropriate use of genetic test results in insurance underwriting, to promote education and training in the financial industry, and to provide support for consumers and health professionals undertaking challenges of adverse decisions.

  9. Plasma transport in stochastic magnetic fields. I. General considerations and test particle transport

    International Nuclear Information System (INIS)

    Krommes, J.A.; Kleva, R.G.; Oberman, C.

    1978-05-01

    A systematic theory is developed for the computation of electron transport in stochastic magnetic fields. Small scale magnetic perturbations arising, for example, from finite-β micro-instabilities are assumed to destroy the flux surfaces of a standard tokamak equilibrium. Because the magnetic lines then wander in a volume, electron radial flux is enhanced due to the rapid particle transport along as well as across the lines. By treating the magnetic lines as random variables, it is possible to develop a kinetic equation for the electron distribution function. This is solved approximately to yield the diffusion coefficient

  10. Plasma transport in stochastic magnetic fields. I. General considerations and test particle transport

    Energy Technology Data Exchange (ETDEWEB)

    Krommes, J.A.; Kleva, R.G.; Oberman, C.

    1978-05-01

    A systematic theory is developed for the computation of electron transport in stochastic magnetic fields. Small scale magnetic perturbations arising, for example, from finite-..beta.. micro-instabilities are assumed to destroy the flux surfaces of a standard tokamak equilibrium. Because the magnetic lines then wander in a volume, electron radial flux is enhanced due to the rapid particle transport along as well as across the lines. By treating the magnetic lines as random variables, it is possible to develop a kinetic equation for the electron distribution function. This is solved approximately to yield the diffusion coefficient.

  11. Overview of toroidal momentum transport

    International Nuclear Information System (INIS)

    Peeters, A.G.; Hornsby, W.A.; Angioni, C.; Hein, T.; Kluy, N.; Strintzi, D.; Tardini, G.; Bortolon, A.; Camenen, Y.; Casson, F.J.; Snodin, A.P.; Szepesi, G.; Duval, B.; Fiederspiel, L.; Idomura, Y.; Mantica, P.; Parra, F.I.; Tala, T.; De Vries, P.; Weiland, J.

    2011-01-01

    Toroidal momentum transport mechanisms are reviewed and put in a broader perspective. The generation of a finite momentum flux is closely related to the breaking of symmetry (parity) along the field. The symmetry argument allows for the systematic identification of possible transport mechanisms. Those that appear to lowest order in the normalized Larmor radius (the diagonal part, Coriolis pinch, E x B shearing, particle flux, and up-down asymmetric equilibria) are reasonably well understood. At higher order, expected to be of importance in the plasma edge, the theory is still under development.

  12. Designing for transportation management and operations : a primer.

    Science.gov (United States)

    2013-02-01

    This primer is focused on the collaborative and systematic consideration of management and operations during transportation : project design and development. This is termed designing for operations. Effectively designing for operations involves...

  13. Resolution and systematic limitations in beam based alignment

    Energy Technology Data Exchange (ETDEWEB)

    Tenenbaum, P.G.

    2000-03-15

    Beam based alignment of quadrupoles by variation of quadrupole strength is a widely-used technique in accelerators today. The authors describe the dominant systematic limitation of this technique, which arises from the change in the center position of the quadrupole as the strength is varied, and derive expressions for the resulting error. In addition, the authors derive an expression for the statistical resolution of such techniques in a periodic transport line, given knowledge of the line's transport matrices, the resolution of the beam position monitor system, and the details of the strength variation procedure. These results are applied to the Next Linear Collider main linear accelerator, an 11 kilometer accelerator containing 750 quadrupoles and 5,000 accelerator structures. The authors find that in principle a statistical resolution of 1 micron is easily achievable but the systematic error due to variation of the magnetic centers could be several times larger.

  14. Genetic discrimination in health insurance: current legal protections and industry practices.

    Science.gov (United States)

    Pollitz, Karen; Peshkin, Beth N; Bangit, Eliza; Lucia, Kevin

    2007-01-01

    Most states have enacted genetic nondiscrimination laws in health insurance, and federal legislation is pending in Congress. Scientists worry fear of discrimination discourages some patients from participating in clinical trials and hampers important medical research. This paper describes a study of medical underwriting practices in the individual health insurance market related to genetic information. Underwriters from 23 companies participated in a survey that asked them to underwrite four pairs of hypothetical applicants for health insurance. One person in each pair had received a positive genetic test result indicating increased risk of a future health condition--breast cancer, hemochromatosis, or heart disease--for a total of 92 underwriting decisions on applications involving genetic information. In seven of these 92 applications, underwriters said they would deny coverage, place a surcharge on premiums,or limit covered benefits based on an applicant's genetic information.

  15. Sediment transport via needle ice: a new method for diffusive transport on laboratory-scale hillslopes

    Science.gov (United States)

    Sweeney, K. E.; Roering, J. J.; Rempel, A. W.

    2012-12-01

    controlled by systematically varying the frequency and/or duration of temperature perturbations. The rate of sediment transport on soil mantled hillslopes depends on topographic slope and transport occurs in an "active layer", i.e., the soil mantle. We show that needle ice transports sediment diffusively and has great potential as a method for laboratory simulation of a soil-mantled hillslope since transport is confined to a layer only a few millimeters from the surface. Furthermore, while past experiments are limited to modeling landscape response to precipitation or uplift, our method to systematically control the vigor of hillslope processes will enable us to model potential climate-driven changes in hillslope transport efficiency.

  16. Quality assurance in the transport of radiography sources

    International Nuclear Information System (INIS)

    Parihar, Manju; Singh, R.K.; Upadhyay, K.C.; Agarwal, S.P.

    2001-01-01

    One of the applications of radioisotopes in industry is non destructive testing (NDT) where the industrial radiography sources are often transported in public domain for site radiography. About 1100 cameras are deployed in our country. This transport of the sources can lead to significant radiological impact in case of accidents unless all precautions are taken. It is, therefore, required to have a systematic programme of controls and inspections in the transport of radioactive source. In this paper, we discuss the quality assurance programme that should be applied in various stages of the transport of radioactive sources to ensure a safe transport and prompt delivery of the radioactive consignment at its destination. (author)

  17. WHO Environmental Noise Guidelines for the European Region: A Systematic Review of Transport Noise Interventions and Their Impacts on Health.

    Science.gov (United States)

    Brown, Alan Lex; van Kamp, Irene

    2017-08-03

    This paper describes a systematic review (1980-2014) of evidence on effects of transport noise interventions on human health. The sources are road traffic, railways, and air traffic. Health outcomes include sleep disturbance, annoyance, cognitive impairment of children and cardiovascular diseases. A conceptual framework to classify noise interventions and health effects was developed. Evidence was thinly spread across source types, outcomes, and intervention types. Further, diverse intervention study designs, methods of analyses, exposure levels, and changes in exposure do not allow a meta-analysis of the association between changes in noise level and health outcomes, and risk of bias in most studies was high. However, 43 individual transport noise intervention studies were examined (33 road traffic; 7 air traffic; 3 rail) as to whether the intervention was associated with a change in health outcome. Results showed that many of the interventions were associated with changes in health outcomes irrespective of the source type, the outcome or intervention type (source, path or infrastructure). For road traffic sources and the annoyance outcome, the expected effect-size can be estimated from an appropriate exposure-response function, though the change in annoyance in most studies was larger than could be expected based on noise level change.

  18. Investment Banking and Analyst Objectivity: Evidence from Forecasts and Recommendations of Analysts Affiliated with M&A Advisors

    OpenAIRE

    Kolasinski, Adam; Kothari, S.P.

    2004-01-01

    Previous research finds some evidence that analysts affiliated with equity underwriters issue more optimistic earnings growth forecasts and optimistic recommendations of client stock than unaffiliated analysts. Unfortunately, these studies are unable to discriminate between three competing hypotheses for the apparent optimism. Under the bribery hypothesis, underwriting clients, with the promise of underwriting fees, coax analysts to compromise their objectivity. The execution-related conflict...

  19. Optimal transport on supply-demand networks.

    Science.gov (United States)

    Chen, Yu-Han; Wang, Bing-Hong; Zhao, Li-Chao; Zhou, Changsong; Zhou, Tao

    2010-06-01

    In the literature, transport networks are usually treated as homogeneous networks, that is, every node has the same function, simultaneously providing and requiring resources. However, some real networks, such as power grids and supply chain networks, show a far different scenario in which nodes are classified into two categories: supply nodes provide some kinds of services, while demand nodes require them. In this paper, we propose a general transport model for these supply-demand networks, associated with a criterion to quantify their transport capacities. In a supply-demand network with heterogeneous degree distribution, its transport capacity strongly depends on the locations of supply nodes. We therefore design a simulated annealing algorithm to find the near optimal configuration of supply nodes, which remarkably enhances the transport capacity compared with a random configuration and outperforms the degree target algorithm, the betweenness target algorithm, and the greedy method. This work provides a start point for systematically analyzing and optimizing transport dynamics on supply-demand networks.

  20. Predicting long-range transport: a systematic evaluation of two multimedia transport models.

    Science.gov (United States)

    Bennett, D H; Scheringer, M; McKone, T E; Hungerbühler, K

    2001-03-15

    The United Nations Environment Program has recently developed criteria to identify and restrict chemicals with a potential for persistence and long-range transport (persistent organic pollutants or POPs). There are many stakeholders involved, and the issues are not only scientific but also include social, economic, and political factors. This work focuses on one aspect of the POPs debate, the criteria for determining the potential for long-range transport (LRT). Our goal is to determine if current models are reliable enough to support decisions that classify a chemical based on the LRT potential. We examine the robustness of two multimedia fate models for determining the relative ranking and absolute spatial range of various chemicals in the environment. We also consider the effect of parameter uncertainties and the model uncertainty associated with the selection of an algorithm for gas-particle partitioning on the model results. Given the same chemical properties, both models give virtually the same ranking. However, when chemical parameter uncertainties and model uncertainties such as particle partitioning are considered, the spatial range distributions obtained for the individual chemicals overlap, preventing a distinct rank order. The absolute values obtained for the predicted spatial range or travel distance differ significantly between the two models for the uncertainties evaluated. We find that to evaluate a chemical when large and unresolved uncertainties exist, it is more informative to use two or more models and include multiple types of uncertainty. Model differences and uncertainties must be explicitly confronted to determine how the limitations of scientific knowledge impact predictions in the decision-making process.

  1. Purchasing a General Ticket for Public Transport - A Means-End Approach

    OpenAIRE

    Wittmer, Andreas; Riegler, Barbara

    2014-01-01

    Switzerland offers a dense network of public transport means. The Swiss General Ticket (GT) is a popular travel pass, which allows the use of most of the public transport facilities in Switzerland. The buying behavior for public transport general tickets underlies a complex decision process. Public transport customers can deal with the complexity in two ways: either one decides on choice heuristics according to ones rather emotional beliefs or decides systematically based on a rational price ...

  2. Electrolyte solution transport in electropolar nanotubes

    International Nuclear Information System (INIS)

    Zhao Jianbing; Culligan, Patricia J; Chen Xi; Qiao Yu; Zhou Qulan; Li Yibing; Tak, Moonho; Park, Taehyo

    2010-01-01

    Electrolyte transport in nanochannels plays an important role in a number of emerging areas. Using non-equilibrium molecular dynamics (NEMD) simulations, the fundamental transport behavior of an electrolyte/water solution in a confined model nanoenvironment is systematically investigated by varying the nanochannel dimension, solid phase, electrolyte phase, ion concentration and transport rate. It is found that the shear resistance encountered by the nanofluid strongly depends on these material/system parameters; furthermore, several effects are coupled. The mechanisms of the nanofluidic transport characteristics are explained by considering the unique molecular/ion structure formed inside the nanochannel. The lower shear resistance observed in some of the systems studies could be beneficial for nanoconductors, while the higher shear resistance (or higher effective viscosity) observed in other systems might enhance the performance of energy dissipation devices.

  3. Guidelines for developing transportation management plans in Virginia.

    Science.gov (United States)

    2005-01-01

    A transportation management plan (TMP) is a comprehensive program of traffic control, communication, operation, and demand management strategies designed to maintain acceptable levels of traffic flow in work zones. A systematic procedure and/or check...

  4. Transportation Business Plan: strategy options document

    International Nuclear Information System (INIS)

    1984-10-01

    This document provides the framework for development of a business plan for establishing and operating the transportation system necessary to support a repository. Section I contains introductory material and defines the plan in terms of policy basis, purpose, and scope of business activities. Section II discusses the evolving strategy that will direct the Department's business actions and describes various strategy options that are under consideration. Also discussed in Section II is a process for the systematic development and acquisition of the transportation system. This process is based on a phased development approach with business activities divided into four stages: system definition; engineering development and certification; cask fleet procurement and carrier negotiations; and transportation operations. 8 figures, 2 tables

  5. Transport Coefficients from Large Deviation Functions

    Directory of Open Access Journals (Sweden)

    Chloe Ya Gao

    2017-10-01

    Full Text Available We describe a method for computing transport coefficients from the direct evaluation of large deviation functions. This method is general, relying on only equilibrium fluctuations, and is statistically efficient, employing trajectory based importance sampling. Equilibrium fluctuations of molecular currents are characterized by their large deviation functions, which are scaled cumulant generating functions analogous to the free energies. A diffusion Monte Carlo algorithm is used to evaluate the large deviation functions, from which arbitrary transport coefficients are derivable. We find significant statistical improvement over traditional Green–Kubo based calculations. The systematic and statistical errors of this method are analyzed in the context of specific transport coefficient calculations, including the shear viscosity, interfacial friction coefficient, and thermal conductivity.

  6. Transport Coefficients from Large Deviation Functions

    Science.gov (United States)

    Gao, Chloe; Limmer, David

    2017-10-01

    We describe a method for computing transport coefficients from the direct evaluation of large deviation function. This method is general, relying on only equilibrium fluctuations, and is statistically efficient, employing trajectory based importance sampling. Equilibrium fluctuations of molecular currents are characterized by their large deviation functions, which is a scaled cumulant generating function analogous to the free energy. A diffusion Monte Carlo algorithm is used to evaluate the large deviation functions, from which arbitrary transport coefficients are derivable. We find significant statistical improvement over traditional Green-Kubo based calculations. The systematic and statistical errors of this method are analyzed in the context of specific transport coefficient calculations, including the shear viscosity, interfacial friction coefficient, and thermal conductivity.

  7. Dry Port Development: A Systematic Review

    Directory of Open Access Journals (Sweden)

    Fatimazahra BENTALEB

    2015-12-01

    Full Text Available Studies on dry ports as nodes in multimodal transport have been expanded to decrease the mounting congestion on seaports. The principal objective of this study is to inspect how dry port researches have been conducted from different perspective. This paper tries to recap the existing researches that aimed to study dry port concept via a systematic review, to present a general overview of the researches on our relevant region and propose a classification for these researches. This paper present a systematic review of dry port that looks to illustrate the progress of researches on this area between 1986 and 2015, collecting researches on dry port concept and analyzing the main characteristics of the dry port development and their contribution to the multimodal transport. The results indicated that most dry port studies considerate the strategic level and concentrate in the Asian continent. Studies regarding other decision levels and continents have to be developed in further researches. Although the existing studies make a contribution in dry port concept, they allow gaps in terms of operational and tactical decision levels considering their limited geographical region.

  8. The concept of and factors affecting transport accessibility of seaports

    Directory of Open Access Journals (Sweden)

    Janusz Dąbrowski

    2012-03-01

    Full Text Available Transport accessibility of seaports is a frequently studied area in economic research. In practice, port operators and authorities use it to promote their services and compete in the market. Up to this day, theoretical basis of seaports transport accessibility has not been properly described. The article attempts to systematize and expend the knowledge in this field. New definitions of transport availability from wider and narrower perspectives were suggested; different types of accessibility and their mutual relations were explained. These ideas were complemented by introducing classification of factors affecting transport accessibility of seaports.

  9. Medicago truncatula transporter database: a comprehensive database resource for M. truncatula transporters

    Directory of Open Access Journals (Sweden)

    Miao Zhenyan

    2012-02-01

    Full Text Available Abstract Background Medicago truncatula has been chosen as a model species for genomic studies. It is closely related to an important legume, alfalfa. Transporters are a large group of membrane-spanning proteins. They deliver essential nutrients, eject waste products, and assist the cell in sensing environmental conditions by forming a complex system of pumps and channels. Although studies have effectively characterized individual M. truncatula transporters in several databases, until now there has been no available systematic database that includes all transporters in M. truncatula. Description The M. truncatula transporter database (MTDB contains comprehensive information on the transporters in M. truncatula. Based on the TransportTP method, we have presented a novel prediction pipeline. A total of 3,665 putative transporters have been annotated based on International Medicago Genome Annotated Group (IMGAG V3.5 V3 and the M. truncatula Gene Index (MTGI V10.0 releases and assigned to 162 families according to the transporter classification system. These families were further classified into seven types according to their transport mode and energy coupling mechanism. Extensive annotations referring to each protein were generated, including basic protein function, expressed sequence tag (EST mapping, genome locus, three-dimensional template prediction, transmembrane segment, and domain annotation. A chromosome distribution map and text-based Basic Local Alignment Search Tools were also created. In addition, we have provided a way to explore the expression of putative M. truncatula transporter genes under stress treatments. Conclusions In summary, the MTDB enables the exploration and comparative analysis of putative transporters in M. truncatula. A user-friendly web interface and regular updates make MTDB valuable to researchers in related fields. The MTDB is freely available now to all users at http://bioinformatics.cau.edu.cn/MtTransporter/.

  10. MODERN AND PERSPECTIVE ON-BOARD NTELLECTUAL TRANSPORT SYSTEMS

    Directory of Open Access Journals (Sweden)

    V. Topalidi

    2011-01-01

    Full Text Available For the purpose of systematization of modern and perspective intellectual transport sides systems (ITВS it is suggested their classification and planning of new ITВS for realization of safety control of vehicle technical condition.

  11. Spatial politics and infrastructure development: Analysis of historical transportation data in Gauteng - South Africa (1975–2003

    Directory of Open Access Journals (Sweden)

    McKay Tracey

    2017-03-01

    Full Text Available If South Africa’s Gauteng Province is to become a more ‘sustainable’, urbanised region, attention needs to be paid to building a transportation network that aligns with sustainable development principles. Currently, public transport passenger levels are low, whilst the geographical area it serves is large and becoming larger. This study analysed the long term, historical transportation trends of Gauteng by comparing four transport studies undertaken between 1975 and 2003. It reveals that an adherence to the ‘predict and provide’ transportation planning model has systematically enhanced road infrastructure over rail, and private over public transport. Effective, efficient and low cost public transport has been systematically under-provisioned; while a reliance on private vehicles is now entrenched and systemic. Racial segregation, spatial apartheid and weak urban land use planning, has resulted in an entrenched, low-density urban sprawl. Lastly, there is the need to collect comparable, longitudinal transportation data, if the successes and failures of policies are to be monitored.

  12. Ion transport in stellarators

    International Nuclear Information System (INIS)

    Ho, D.D.M.; Kulsrud, R.M.

    1985-09-01

    Stellarator ion transport in the low-collisionality regime with a radial electric field is calculated by a systematic expansion of the drift-Boltzmann equation. The shape of the helical well is taken into account in this calculation. It is found that the barely trapped ions with three to four times the thermal energy give the dominant contribution to the diffusion. Expressions for the ion particle and energy fluxes are derived

  13. Transport Emissions and Energy Consumption Impacts of Private Capital Investment in Public Transport

    Directory of Open Access Journals (Sweden)

    Yunqiang Xue

    2017-10-01

    Full Text Available Introducing private capital into the public transport system for its sustainable development has been increasing around the world. However, previous research ignores emissions and energy consumption impacts, which are important for private capital investment policy-making. To address this problem, the system dynamic (SD approach was used to quantitatively analyze the cumulative effects of different private capital investment models in public transport from the environmental perspective. The SD model validity was verified in the case study of Jinan public traffic. Simulation results show that the fuel consumption and emission reductions are obvious when the private capital considering passenger value invests in public transport compared with the no private capital investment and traditional investment models. There are obvious cumulative reductions for fuel consumption, CO2, CO, SO2, and PM10 emissions for 100 months compared with no private capital investment. This research verifies the superiority of the passenger value investment model in public transport from the environmental point of view, and supplies a theoretical tool for administrators to evaluate the private capital investment effects systematically.

  14. Applications of a systematic homogenization theory for nodal diffusion methods

    International Nuclear Information System (INIS)

    Zhang, Hong-bin; Dorning, J.J.

    1992-01-01

    The authors recently have developed a self-consistent and systematic lattice cell and fuel bundle homogenization theory based on a multiple spatial scales asymptotic expansion of the transport equation in the ratio of the mean free path to the reactor characteristics dimension for use with nodal diffusion methods. The mathematical development leads naturally to self-consistent analytical expressions for homogenized diffusion coefficients and cross sections and flux discontinuity factors to be used in nodal diffusion calculations. The expressions for the homogenized nuclear parameters that follow from the systematic homogenization theory (SHT) are different from those for the traditional flux and volume-weighted (FVW) parameters. The calculations summarized here show that the systematic homogenization theory developed recently for nodal diffusion methods yields accurate values for k eff and assembly powers even when compared with the results of a fine mesh transport calculation. Thus, it provides a practical alternative to equivalence theory and GET (Ref. 3) and to simplified equivalence theory, which requires auxiliary fine-mesh calculations for assemblies embedded in a typical environment to determine the discontinuity factors and the equivalent diffusion coefficient for a homogenized assembly

  15. Lack of association between the Serotonin Transporter Promoter Polymorphism (5-HTTLPR and Panic Disorder: a systematic review and meta-analysis

    Directory of Open Access Journals (Sweden)

    Manfro Gisele G

    2007-08-01

    Full Text Available Abstract Background The aim of this study is to assess the association between the Serotonin Transporter Promoter Polymorphism (5-HTTLPR and Panic Disorder (PD. Methods This is a systematic review and meta-analysis of case-control studies with unrelated individuals of any ethnic origin examining the role of the 5-HTTLPR in PD according to standard diagnostic criteria (DSM or ICD. Articles published in any language between January 1996 and April 2007 were eligible. The electronic databases searched included PubMed, PsychInfo, Lilacs and ISI. Two separate analyses were performed: an analysis by alleles and a stratified analysis separating studies by the quality of control groups. Asymptotic DerSimonian and Laird's Q test were used to assess heterogeneity. Results of individual studies were combined using the fixed effect model with respective 95% confidence intervals. Results Nineteen potential articles were identified, and 10 studies were included in this meta-analysis. No statistically significant association between 5-HTTLPR and PD was found, OR = 0.91 (CI95% 0.80 to 1.03, p = 0.14. Three sub-analyses divided by ethnicity, control group quality and Agoraphobia comorbidity also failed to find any significant association. No evidence of heterogeneity was found between studies in the analyses. Conclusion Results from this systematic review do not provide evidence to support an association between 5-HTTLPR and PD. However, more studies are needed in different ethnic populations in order to evaluate a possible minor effect.

  16. Advanced transport systems analysis, modeling, and evaluation of performances

    CERN Document Server

    Janić, Milan

    2014-01-01

    This book provides a systematic analysis, modeling and evaluation of the performance of advanced transport systems. It offers an innovative approach by presenting a multidimensional examination of the performance of advanced transport systems and transport modes, useful for both theoretical and practical purposes. Advanced transport systems for the twenty-first century are characterized by the superiority of one or several of their infrastructural, technical/technological, operational, economic, environmental, social, and policy performances as compared to their conventional counterparts. The advanced transport systems considered include: Bus Rapid Transit (BRT) and Personal Rapid Transit (PRT) systems in urban area(s), electric and fuel cell passenger cars, high speed tilting trains, High Speed Rail (HSR), Trans Rapid Maglev (TRM), Evacuated Tube Transport system (ETT), advanced commercial subsonic and Supersonic Transport Aircraft (STA), conventionally- and Liquid Hydrogen (LH2)-fuelled commercial air trans...

  17. Influence of 3D printing on transport : a theory and experts judgment based conceptual model

    NARCIS (Netherlands)

    Boon, Wouter; Van Wee, Bert

    2017-01-01

    Consumer 3D printing is on the rise and has the potential to significantly change the transport and logistics sector. Current literature on 3D printing and transport studies does not provide a systematic model of the impact of 3D printing on transport and related (policy relevant) areas, such as

  18. Kinetic theory and transport phenomena

    CERN Document Server

    Soto, Rodrigo

    2016-01-01

    This textbook presents kinetic theory, which is a systematic approach to describing nonequilibrium systems. The text is balanced between the fundamental concepts of kinetic theory (irreversibility, transport processes, separation of time scales, conservations, coarse graining, distribution functions, etc.) and the results and predictions of the theory, where the relevant properties of different systems are computed. The book is organised in thematic chapters where different paradigmatic systems are studied. The specific features of these systems are described, building and analysing the appropriate kinetic equations. Specifically, the book considers the classical transport of charges, the dynamics of classical gases, Brownian motion, plasmas, and self-gravitating systems, quantum gases, the electronic transport in solids and, finally, semiconductors. Besides these systems that are studied in detail, concepts are applied to some modern examples including the quark–gluon plasma, the motion of bacterial suspen...

  19. Two-echelon transportation optimisation: a meta-narrative analysis

    Directory of Open Access Journals (Sweden)

    Jesus Gonzalez-Feliu

    2011-02-01

    Full Text Available Freight transportation constitutes one of the main activities that influences economy and society, as it assures a vital link between suppliers and customers and it represents a major source of employment. Multi-echelon distribution is one of the most common strategies adopted by the transportation companies in an aim of cost reduction. Although vehicle routing problems are very common in operational research, they are essentially related to single-echelon cases. This paper presents the main concepts of multi-echelon distribution with cross-docks and a unified notation for two-chelon transportation cost optimization. A systematic review is also presented, in order to list the main issues and methods that can be helpful for scientists and transportation practitioners.

  20. Salt Repository Project transportation program plan

    International Nuclear Information System (INIS)

    Fisher, R.L.; Greenberg, A.H.; Anderson, T.L.; Yates, K.R.

    1987-01-01

    The Salt Repository Project (SRP) has the responsibility to develop a comprehensive transportation program plan (TrPP) that treats the transportation of workers, supplies, and high-level radioactive waste to the site and the transportation of salt, low-level, and transuranic wastes from the site. The TrPP has developed a systematic approach to transportation which is directed towards satisfying statutes, regulations, and directives and is guided by a hierarchy of specific functional requirements, strategies, plans, and reports. The TrPP identifies and develops the planning process for transportation-related studies and provides guidance to staff in performing and documenting these activities. The TrPP also includes an explanation of the responsibilities of the organizational elements involved in these transportation studies. Several of the report chapters relate to identifying routes for transporting nuclear waste to the site. These include a chapter on identifying an access corridor for a new rail route leading to the site, identifying and evaluating emergency-response preparedness capabilities along candidate routes in the state, and identifying alternative routes from the state border, ports, or in-state reactors to the site. The TrPP also includes plans for identifying salt disposal routes and a discussion of repository/transportation interface requirements. 89 refs., 6 figs

  1. Tritium source-related systematic uncertainties of the KATRIN experiment

    Energy Technology Data Exchange (ETDEWEB)

    Seitz-Moskaliuk, Hendrik [Karlsruher Institut fuer Technologie, Institut fuer experimentelle Kernphysik, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany); Collaboration: KATRIN-Collaboration

    2016-07-01

    KATRIN will perform a direct, kinematics-based measurement of the neutrino mass with a sensitivity of 200 meV (90 % C. L.) reached after 3 years of measurement time. The neutrino mass is obtained by determining the shape of the spectrum of tritium β decay electrons close to the endpoint of 18.6 keV with a spectrometer of MAC-E filter type. To achieve the planned sensitivity, the systematic measurement uncertainties have to be carefully controlled and evaluated. Main sources of systematics are the MAC-E filter on the one hand and the source and transport section (STS) on the other hand. Most of the operational parameters of KATRIN have to be stable at or even below the per mille level and have to meet further strict requirements. This talk reviews the KATRIN systematics with a special focus on the STS. Early commissioning measurements to determine the main systematics are introduced.

  2. DIRECTION OF MODERNIZATION OF THE ARCTIC MARINE TRANSPORTATION SYSTEM

    Directory of Open Access Journals (Sweden)

    N. I. Komkov

    2014-01-01

    Full Text Available The article deals with the modern processes of formation and development of the marine transportation system in the Russian Arctic, analyzes its problem areas and reserves growth. Shows the status and prospects of development of cargo specialized fl eet of ice-class and icebreakers. Particular attention is paid to infrastructure, port management, port The possibility of creating special economic zones. Systematized direction of modernization of the Arctic marine transportation system.

  3. 17 CFR 229.508 - (Item 508) Plan of distribution.

    Science.gov (United States)

    2010-04-01

    ... business function of such underwriter(s) will be to sell the securities to be registered, or that the... acquisition, reorganization, readjustment or succession, describe briefly the general effect of the plan and...

  4. Nonlocal transport in hot plasma. Part I

    International Nuclear Information System (INIS)

    Brantov, A. V.; Bychenkov, V. Yu.

    2013-01-01

    The problem of describing charged particle transport in hot plasma under the conditions in which the ratio of the electron mean free path to the gradient length is not too small is one of the key problems of plasma physics. However, up to now, there was a deficit of the systematic interpretation of the current state of this problem, which, in most studies, is formulated as the problem of nonlocal transport. In this review, we fill this gap by presenting a self-consistent linear theory of nonlocal transport for small plasma perturbations and an arbitrary collisionality from the classical highly collisional hydrodynamic regime to the collisionless regime. We describe a number of nonlinear transport models and demonstrate the application of the nonclassical transport theory to the solution of some problems of plasma physics, first of all for plasmas produced by nanosecond laser pulses with intensities of 10 13 –10 16 W/cm 2

  5. Securities regulation and implicit penalties

    Directory of Open Access Journals (Sweden)

    Donghua Chen

    2011-06-01

    Full Text Available The extant literature offers extensive support for the significant role played by institutions in financial markets, but implicit regulation and monitoring have yet to be examined. This study fills this void in the literature by employing unique Chinese datasets to explore the implicit regulation and penalties imposed by the Chinese government in regulating the initial public offering (IPO market. Of particular interest are the economic consequences of underwriting IPO deals for client firms that violate regulatory rules in China’s capital market. We provide evidence to show that the associated underwriters’ reputations are impaired and their market share declines. We further explore whether such negative consequences result from a market disciplinary mechanism or a penalty imposed by the government. To analyze the possibility of a market disciplinary mechanism at work, we investigate (1 the market reaction to other client firms whose IPO deals were underwritten by underwriters associated with a violation at the time the violation was publicly disclosed and (2 the under-pricing of IPO deals undertaken by these underwriters after such disclosure. To analyze whether the government imposes an implicit penalty, we examine the application processing time for future IPO deals underwritten by the associated underwriters and find it to be significantly longer than for IPO deals underwritten by other underwriters. Overall, there is little evidence to suggest that the market penalizes underwriters for the rule-violating behavior of their client firms in China. Instead, the Chinese government implicitly penalizes them by imposing more stringent criteria on and lengthening the processing time of the IPO deals they subsequently underwrite.

  6. Indicators and beyond: Assessing the sustainability of transport projects

    DEFF Research Database (Denmark)

    Cornet, Yannick

    2016-01-01

    on the topic of sustainable transport indicator frameworks. Case study work draws upon extensive desktop-based analysis of impact assessment reports and other publically available material about real cases of large transport infrastructure appraisals. The HS2 high-speed rail (HSR) project appraisal in the UK......Credibly demonstrating actual progress towards a genuinely sustainable transport situation remains a challenge. A key problem is that the incorporation of sustainability in transport policy and planning at present is not systematic. A motivating assumption behind this thesis is that a transition...... toward a sustainable transport system will require strong support from decision-support processes and assessment tools that do not only adopt the language of sustainability, but fully integrate an explicit notion of sustainability in all of their conceptual, operational and procedural approaches...

  7. [Concrete pain prevention measures regarding hospital internal transport in a cancer center].

    Science.gov (United States)

    Nebbak, Jean-Marie; Vignozzi, Annick; Bussy, Catherine; Charleux, Diane; Laplanche, Agnès; Mathivon, Delphine; Di Palma, Mario

    2013-01-01

    Iatrogenic pain is a common problem for cancer patients, including those due to hospital internal transport. An original prospective study conducted in 2006 allowed risk factor identification, and from 2007, a pluri-annual progress plan was implemented. Its actions were systematically evaluated and all phases of transportation reconsidered: preparation, patient transport to and care in medicotechnical units. Measures applied to anticipate these pains help improve the quality of hospital care. All professionals involved in the patient transportation system need to be made aware of this and not only hospital porters.

  8. Prioritising transport infrastructure projects: Towards a multi-criterion ...

    African Journals Online (AJOL)

    Southern African Business Review ... systematic framework for the appraisal of transport infrastructure projects of the type 'budget cycle projects with local ... Cost/benefit analysis, when applied in a classic sense, is not suitable for this purpose, given its ... (optimal allocation of resources), equity (impact distribution aspects),

  9. Application of radiation protection programmes to transport of radioactive material

    International Nuclear Information System (INIS)

    Lopez Vietri, Jorge; Capadona, Nancy; Barenghi, Leonardo

    2008-01-01

    Full text: The principles for implementing radiation protection programmes (RPP) are detailed in the draft IAEA safety guide TS-G-1.5 'Radiation protection programmes for transport of radioactive material'. The document is described in this paper and analysis is made for typical applications to current operations carried out by consignors, carriers and consignees. Systematic establishment and application of RPPs is a way to control radiological protection during different steps of transport activity. The most widely transported packages in the world are radiopharmaceuticals by road. It is described an application of RPP for an organization involved in road transport of Type A packages containing radiopharmaceuticals. Considerations based on the radionuclides, quantities and activities transported are the basis to design and establish the scope of the RPP for the organizations involved in transport. Next stage is the determination of roles and responsibilities for each activity related to transport of radioactive materials. An approach to the dose received by workers is evaluated considering the type, category and quantity of packages, the radionuclides, the frequency of consignments and how long are the storages. The average of transports made in the last years must be taken into account and special measures intended to optimize the protection are evaluated. Tasks like monitoring, control of surface contamination and segregation measures, are designed based on the dose evaluation and optimization. The RPP also indicates main measures to follow in case of emergency during transport taking account of radionuclides, activities and category of packages for different accident scenarios. Basis for training personnel involved in handling of radioactive materials to insure they have appropriate knowledge about preparing packages, measuring dose rates, calculating transport index, labelling, marking and placarding, transport documents, etc, are considered. The RPP is a part

  10. Socioeconomic inequalities in occupational, leisure-time, and transport related physical activity among European adults: A systematic review

    NARCIS (Netherlands)

    M.A. Beenackers (Marielle); C.B.M. Kamphuis (Carlijn); K. Giskes (Katrina); J. Brug (Hans); A.E. Kunst (Anton); A. Burdorf (Alex); F.J. van Lenthe (Frank)

    2012-01-01

    textabstractBackground: This study systematically reviewed the evidence pertaining to socioeconomic inequalities in different domains of physical activity (PA) by European region.Methods: Studies conducted between January 2000 and December 2010 were identified by a systematic search in Pubmed,

  11. Socioeconomic inequalities in occupational, leisure-time, and transport related physical activity among European adults: A systematic review

    NARCIS (Netherlands)

    Beenackers, Marielle A.; Kamphuis, Carlijn B. M.; Giskes, Katrina; Brug, Johannes; Kunst, Anton E.; Burdorf, Alex; van Lenthe, Frank J.

    2012-01-01

    Background: This study systematically reviewed the evidence pertaining to socioeconomic inequalities in different domains of physical activity (PA) by European region. Methods: Studies conducted between January 2000 and December 2010 were identified by a systematic search in Pubmed, Embase, Web of

  12. New organic photorefractive material composed of a charge-transporting dendrimer and a stilbene chromophore

    Science.gov (United States)

    Bai, Jaeil; Ducharme, Stephen; Leonov, Alexei G.; Lu, Liu; Takacs, James M.

    1999-10-01

    In this report, we introduce new organic photorefractive composites consisting of charge transporting den-drimers highly doped with a stilbene nonlinear optic chromophore, The purpose of making these composites is to improve charge transport, by reducing inhomogeneity when compared to ordinary polymer-based systems. Because the structure of this material gives us freedom to control the orientation of charge transport agents synthetically, we can study the charge transport mechanism more systematically than in polymers. We discuss this point and present the characterization results for this material.

  13. The consumption, production and transportation of methanol in China: A review

    International Nuclear Information System (INIS)

    Su, Li-Wang; Li, Xiang-Rong; Sun, Zuo-Yu

    2013-01-01

    Methanol is considered as one of the potential materials for fossil-based fuels because of its available applications in the fields of fuels and chemical materials. China has become the biggest methanol production country since 2006; hence, analysing the consumption, production and transportation of methanol in China has great importance. In the present article, the current status of methanol from production to consumption in China has been systematically described. Chinese industry and statistics data are introduced to analyse and discuss the total and segmental methanol amount in both production and consumption. In China, most of the methanol is primarily consumed in the synthesis of formaldehyde, alternative fuels and acetic acid, with the corresponding percentages of 35.0%, 33.0% and 8.0%. In 2011, about 22.27 million tons of methanol was generated on site, of which, 63.7%, 23.0% and 11.3% were produced by coal, natural gas and coke-oven gas, respectively. As regards transportation, approximately 82.6% of methanol was transported by overland freight, 9.0% by sea and the rest 8.4% by train. - Highlights: • The consumption of methanol in China has been reviewed in detail. • The production of methanol in China has been reviewed in detail. • The transportation of methanol in China has been systematically reviewed

  14. Challenges in Governing the Digital Transportation Ecosystem in Jakarta: A Research Direction in Smart City Frameworks

    Directory of Open Access Journals (Sweden)

    Iqbal Yulizar Mukti

    2018-03-01

    Full Text Available Mobility is one of the most difficult domains of the smart city to face. In fact, most large cities in the world are still facing urban mobility problems, especially traffic congestion. Particularly, in Jakarta, Indonesia, traffic congestion is a major issue that negatively affects productivity and the overall living quality of the citizens. Along with the development of the information communication and technology (ICT, the transportation domain in Jakarta has formed a digital transportation ecosystem, shown by the emergence of innovative digital-based transportation services. In line with this current condition, this paper hopes to contribute to the improvement of urban traffic in Jakarta by proposing research directions to govern the digital transportation ecosystem within a smart city framework. The significance of the research directions is reviewed using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA methodology in a systematic review of previous studies. Ultimately, the research directions proposed in this paper lead to the necessity for an architectural perspective and relevant big data analytical tools to improve the digital transportation ecosystem in Jakarta.

  15. The Logistical Aspects of Freight Transportation and Forwarding

    Directory of Open Access Journals (Sweden)

    Zimina Anna I.

    2017-04-01

    Full Text Available The article substantiates the theoretical and practical aspects of freight transportation and forwarding services based on the principles of logistics. The indicators of dynamics of freight transportation in Ukraine compared to last year and the structure by types of transport have been provided. The indicators of the foreign trade performance of Ukraine have been presented, including the counter-current export and import flows, as well as the external trade balance, which directly impacts the volume and dynamics of freight transportation and forwarding services. The main parameters of the transportation and forwarding logistics system were systematized, taking into consideration the technical and operational characteristics of the rolling stock, the route of communication, and the terminals. The role and features of the functions of the inter/multimodal transportation operators – freight forwarders of the «tonnage customers» have been considered. The article determines principles for the organization of work of freight forwarders, as well as the terms of agreement of the parties when the freight forwarding contract is concluded. The conditions for developing a logistics approach to the implementation of freight transportation and forwarding services have been generalized.

  16. HZETRN radiation transport validation using balloon-based experimental data

    Science.gov (United States)

    Warner, James E.; Norman, Ryan B.; Blattnig, Steve R.

    2018-05-01

    The deterministic radiation transport code HZETRN (High charge (Z) and Energy TRaNsport) was developed by NASA to study the effects of cosmic radiation on astronauts and instrumentation shielded by various materials. This work presents an analysis of computed differential flux from HZETRN compared with measurement data from three balloon-based experiments over a range of atmospheric depths, particle types, and energies. Model uncertainties were quantified using an interval-based validation metric that takes into account measurement uncertainty both in the flux and the energy at which it was measured. Average uncertainty metrics were computed for the entire dataset as well as subsets of the measurements (by experiment, particle type, energy, etc.) to reveal any specific trends of systematic over- or under-prediction by HZETRN. The distribution of individual model uncertainties was also investigated to study the range and dispersion of errors beyond just single scalar and interval metrics. The differential fluxes from HZETRN were generally well-correlated with balloon-based measurements; the median relative model difference across the entire dataset was determined to be 30%. The distribution of model uncertainties, however, revealed that the range of errors was relatively broad, with approximately 30% of the uncertainties exceeding ± 40%. The distribution also indicated that HZETRN systematically under-predicts the measurement dataset as a whole, with approximately 80% of the relative uncertainties having negative values. Instances of systematic bias for subsets of the data were also observed, including a significant underestimation of alpha particles and protons for energies below 2.5 GeV/u. Muons were found to be systematically over-predicted at atmospheric depths deeper than 50 g/cm2 but under-predicted for shallower depths. Furthermore, a systematic under-prediction of alpha particles and protons was observed below the geomagnetic cutoff, suggesting that

  17. Changes in the Trade and Promotion of Passenger Air Transport

    Directory of Open Access Journals (Sweden)

    Cornelia Petroman

    2010-10-01

    Full Text Available Passenger air carriers will be able to systematically overbook transport capacities on certain aerial routes due to the quick adaptation to modern trading means, to the modern promotion of services and to the modern means of information of potential travellers. Though ticket booking in aerial transport made its debut as a simple process of automation of ticket sale, it soon turned into a strong marketing instrument with unexpected effects on competitiveness on the market of tourism aerial transport. The use of modern ways of operating Computer Reservation Systems and Billing Settlement Plans by passenger air companies and by tour operators improves service standards.

  18. Theory of ion heat transport in tokamaks

    International Nuclear Information System (INIS)

    Gott, Y.V.; Yurchenko, E.I.

    1987-01-01

    Experiments which have been carried out in several tokamaks to determine the ion thermal conductivity show that it is several times the value predicted by the neoclassical theory. A possible explanation for this discrepancy is proposed. When the finite width of a banana is taken into account, there are substantial increases in the heat fluxes which stem from the important contribution of superthermal ions to the transport. If the electron diffusive flux is zero, a systematic account of the ions with E>T leads to an ion heat flux with a finite banana width which is two to four times the neoclassical prediction. The effect of the anomalous nature of the electron flux on the ion heat transport is analyzed. An expression is derived for calculating the ion heat transport over the entire range of collision rates

  19. 77 FR 21991 - Federal Housing Administration (FHA): Multifamily Accelerated Processing (MAP)-Lender and...

    Science.gov (United States)

    2012-04-12

    .... This practice would mitigate risk, since MAP lenders and underwriters will now be approved at a tier... Administration (FHA): Multifamily Accelerated Processing (MAP)--Lender and Underwriter Eligibility Criteria and Credit Watch for MAP Lenders AGENCY: Office of the Assistant Secretary for Housing--Federal Housing...

  20. Rail transport systems approach

    CERN Document Server

    2017-01-01

    This book shows how the systems approach is employed by scientists in various countries to solve specific problems concerning railway transport. In particular, the book describes the experiences of scientists from Romania, Germany, the Czech Republic, the UK, Russia, Ukraine, Lithuania and Poland. For many of these countries there is a problem with the historical differences between the railways. In particular, there are railways with different rail gauges, with different signaling and communication systems, with different energy supplies and, finally, with different political systems, which are reflected in the different approaches to the management of railway economies. The book’s content is divided into two main parts, the first of which provides a systematic analysis of individual means of providing and maintaining rail transport. In turn, the second part addresses infrastructure and management development, with particular attention to security issues. Though primarily written for professionals involved...

  1. Axonal collateral-collateral transport of tract tracers in brain neurons: false anterograde labelling and useful tool.

    Science.gov (United States)

    Chen, S; Aston-Jones, G

    1998-02-01

    It is well established that some neuroanatomical tracers may be taken up by local axonal terminals and transported to distant axonal collaterals (e.g., transganglionic transport in dorsal root ganglion cells). However, such collateral-collateral transport of tracers has not been systematically examined in the central nervous system. We addressed this issue with four neuronal tracers--biocytin, biotinylated dextran amine, cholera toxin B subunit, and Phaseolus vulgaris-leucoagglutinin--in the cerebellar cortex. Labelling of distant axonal collaterals in the cerebellar cortex (indication of collateral-collateral transport) was seen after focal iontophoretic microinjections of each of the four tracers. However, collateral-collateral transport properties differed among these tracers. Injection of biocytin or Phaseolus vulgaris-leucoagglutinin in the cerebellar cortex yielded distant collateral labelling only in parallel fibres. In contrast, injection of biotinylated dextran amine or cholera toxin B subunit produced distant collateral labelling of climbing fibres and mossy fibres, as well as parallel fibres. The present study is the first systematic examination of collateral-collateral transport following injection of anterograde tracers in brain. Such collateral-collateral transport may produce false-positive conclusions regarding neural connections when using these tracers for anterograde transport. However, this property may also be used as a tool to determine areas that are innervated by common distant afferents. In addition, these results may indicate a novel mode of chemical communication in the nervous system.

  2. Segmental transports for posttraumatic lower extremity bone defects: are femoral bone transports safer than tibial?

    Science.gov (United States)

    Liodakis, Emmanouil; Kenawey, Mohamed; Krettek, Christian; Ettinger, Max; Jagodzinski, Michael; Hankemeier, Stefan

    2011-02-01

    The long-term outcomes following femoral and tibial segment transports are not well documented. Purpose of the study is to compare the complication rates and life quality scores of femoral and tibial transports in order to find what are the complication rates of femoral and tibial monorail bone transports and if they are different? We retrospectively analyzed the medical records of 8 femoral and 14 tibial consecutive segment transports performed with the monorail technique between 2001 and 2008 in our institution. Mean follow-up was 5.1 ± 2.1 years with a minimum follow-up of 2 years. Aetiology of the defects was posttraumatic in all cases. Four femoral (50%) and nine tibial (64%) fractures were open. The Short Form-36 (SF-36) health survey was used to compare the life quality after femoral and tibial bone transports. The Mann-Whiney U test, Fisher exact test, and the Student's two tailed t-test were used for statistical analysis. P ≤ 0.05 was considered to be statistically significant. The tibial transport was associated with higher rates of severe complications and additional procedures (1.5 ± 0.9 vs. 3.4 ± 2.7, p = 0.048). Three patients of the tibial group were amputated because of recurrent infections and one developed a complete regenerate insufficiency that was treated with partial diaphyseal tibial replacement. Contrary to that none of patients of the femoral group developed a complete regenerate insufficiency or was amputated. Tibial bone transports have a higher rate of complete and incomplete regenerate insufficiency and can more often end in an amputation. The authors suggest systematic weekly controls of the CRP value and of the callus formation in patients with posttraumatic tibia bone transports. Further comparative studies comparing the results of bone transports with and without intramedullary implants are necessary.

  3. Vibronic coupling effect on the electron transport through molecules

    Science.gov (United States)

    Tsukada, Masaru; Mitsutake, Kunihiro

    2007-03-01

    Electron transport through molecular bridges or molecular layers connected to nano-electrodes is determined by the combination of coherent and dissipative processes, controlled by the electron-vibron coupling, transfer integrals between the molecular orbitals, applied electric field and temperature. We propose a novel theoretical approach, which combines ab initio molecular orbital method with analytical many-boson model. As a case study, the long chain model of the thiophene oligomer is solved by a variation approach. Mixed states of moderately extended molecular orbital states mediated and localised by dress of vibron cloud are found as eigen-states. All the excited states accompanied by multiple quanta of vibration can be solved, and the overall carrier transport properties including the conductance, mobility, dissipation spectra are analyzed by solving the master equation with the transition rates estimated by the golden rule. We clarify obtained in a uniform systematic way, how the transport mode changes from a dominantly coherent transport to the dissipative hopping transport.

  4. 76 FR 38891 - Companies Holding Certificates of Authority as Acceptable Sureties on Federal Bonds and as...

    Science.gov (United States)

    2011-07-01

    ...) BUSINESS ADDRESS: 333 S. WABASH AVE, CHICAGO, IL 60604. PHONE: (312) 822-5000. UNDERWRITING LIMITATION b... IN: Indiana. American Fire and Casualty Company (NAIC 24066) BUSINESS ADDRESS: 9450 Seward Road... ADDRESS: 333 S. WABASH AVE, CHICAGO, IL 60604. PHONE: (312) 822-5000. UNDERWRITING LIMITATION b/: $795,783...

  5. Chemical vapour transport of pyrite (FeS 2) with halogen (Cl, Br, I)

    Science.gov (United States)

    Fiechter, S.; Mai, J.; Ennaoui, A.; Szacki, W.

    1986-12-01

    A systematic study of chemical vapour transport (CVT) of pyrite with halogen, hydrogen halides and ammonium halides as transporting agents has shown that the transport with chlorine and bromine in a temperature gradient Δ T = 920-820 K yields the highest transport rates (˜6 mg/h) with crystals up to 5 mm edge length. Computing thermochemical equilibria and flux functions in the system Fe-S-Hal (Hal = Cl, Br, I) it has been confirmed that the transport velocity of pyrite is limited by the concentration of FeHal 2 in the vapour phase, the equilibrium position between FeHal 2(g) and FeHal 3(g) and the flux directions of the iron gas species.

  6. Unstirred Water Layers and the Kinetics of Organic Cation Transport

    Science.gov (United States)

    Shibayama, Takahiro; Morales, Mark; Zhang, Xiaohong; Martinez, Lucy; Berteloot, Alfred; Secomb, Timothy W.; Wright, Stephen H.

    2015-01-01

    Purpose Unstirred water layers (UWLs) present an unavoidable complication in the measurement of transport kinetics in cultured cells and the high rates of transport achieved by overexpressing heterologous transporters exacerbate the UWL effect. This study examined the correlation between measured Jmax and Kt values and the effect of manipulating UWL thickness or transport Jmax on the accuracy of experimentally determined kinetics of the multidrug transporters, OCT2 and MATE1. Methods Transport of TEA and MPP was measured in CHO cells that stably expressed human OCT2 or MATE1. UWL thickness was manipulated by vigorous reciprocal shaking. Several methods were used to manipulate maximal transport rates. Results Vigorous stirring stimulated uptake of OCT2-mediated transport by decreasing apparent Kt (Ktapp) values. Systematic reduction in transport rates was correlated with reduction in Ktapp values. The slope of these relationships indicated a 1500 µm UWL in multiwell plates. Reducing the influence of UWLs (by decreasing either their thickness or the Jmax of substrate transport) reduced Ktapp by 2-fold to >10-fold. Conclusions Failure to take into account the presence of UWLs in experiments using cultured cells to measure transport kinetics can result in significant underestimates of the affinity of multidrug transporters for substrates. PMID:25791216

  7. Mathematical modeling of solute transport in the subsurface

    International Nuclear Information System (INIS)

    Naymik, T.G.

    1987-01-01

    A review of key works on solute transport models indicates that solute transport processes with the exception of advection are still poorly understood. Solute transport models generally do a good job when they are used to test scientific concepts and hypotheses, investigate natural processes, systematically store and manage data, and simulate mass balance of solutes under certain natural conditions. Solute transport models generally are not good for predicting future conditions with a high degree of certainty, or for determining concentrations precisely. The mathematical treatment of solute transport far surpasses their understanding of the process. Investigations of the extent of groundwater contamination and methods to remedy existing problems show the along-term nature of the hazard. Industrial organic compounds may be immiscible in water, highly volatile, or complexed with inorganic as well as other organic compounds; many remain stable in nature almost indefinitely. In the worst case, future disposal of hazardous waste may be restricted to deep burial, as is proposed for radioactive wastes. For investigations pertinent to transport of radionuclides from a geologic repository, the process cannot be fully understood without adequate thermodynamic and kinetic data bases

  8. Transport policies related to climate change mitigation: the case of Denmark

    Energy Technology Data Exchange (ETDEWEB)

    Vad Mathiesen, B.; Kappel, J.

    2013-03-15

    This report presents the Danish national policies on reducing the emissions of greenhouse gasses and reducing Denmark's dependency on fossil fuels in the transport sector, as well as some of the results of the policies. Systematic focus on efficient transport and climate mitigation started in 2008 and 2009 with a change - not only in the wording and in the political visions - but also in the actual prioritisation of investments and policies to a very large extent. In March 2012 another milestone was set by the Government, to have Denmark based on 100% renewable energy in 2050. This entails large challenges for the transport sectors, which has not yet been systematically analysed from any Governmental body. In this report we list projects which have done so. The first chapter describes policies and initiatives of international relevance within climate mitigation. The following chapters explain in further debt these policies and their effects as well as a number of additional policies and initiatives related to climate mitigation and transport. The private sector and local government has proven important in connection with an efficient transport sector. Hence selected local and regional projects and their results are introduced as well. To provide an overview of current trends, related scientific projects and other analyses on climate change mitigation and transport are given in the report. The references used in this report can also serve as a source of data and inspiration for the reader. This report is prepared as one of many inputs to the analyses conducted in The Swedish Government's Commission on fossil-free road transport. The task of this Commission is to: ''review alternative developments of fuels and vehicles for fossil-free road transport, to consider measures and policy options that would enable the Swedish road transport system to become climate neutral by 2050, and to propose intermediate emission reduction targets for years such as

  9. 75 FR 81679 - Proposed Collection; Comment Request

    Science.gov (United States)

    2010-12-28

    ... entitled ``Accounting of Segregated Trust Account.'' Rule 27d-1 requires the depositor or principal... investment companies. Rule 27d-1(j) directs depositors and principal underwriters to make an accounting of... certain financial criteria; and (iii) the depositor or principal underwriter must file as an exhibit to...

  10. Personality and risk perception in transport.

    Science.gov (United States)

    Fyhri, Aslak; Backer-Grøndahl, Agathe

    2012-11-01

    Within research on individual variations in risk perception, personality has been suggested as one important factor. In the present study, personality traits (44 items from the Big Five inventory) were investigated in relation to risk perception in transport and transport behavioural adaptations. In a sample of 312 participants, we found that the personality trait 'emotional stability versus neuroticism' was negatively correlated with risk perception (operationalised as "thinking about the possibility") of an accident (-0.38) and an unpleasant incident, such as crime, violence, robbery (-0.25). 'Agreeableness' was also negatively related to risk perception, however first and foremost in relation to perceived risk for unpleasant incidents on transport modes in which one interacts with other people (0.25). Moreover, regression analyses showed that 'emotional stability' was a significant predictor of behavioural adaptations on bus. Regression analyses explained between 17 and 26 percent of variance in behavioural adaptations. The results show that different groups of people vary systematically in their perception of risk in transport. Furthermore, these differences are manifest as a difference in risk-preventive behaviour at a strategic level, i.e. as decisions about avoiding risky situations. Copyright © 2012 Elsevier Ltd. All rights reserved.

  11. The effects of sodium-glucose co-transporter 2 inhibitors in patients with type 2 diabetes

    DEFF Research Database (Denmark)

    Storgaard, Heidi; Gluud, Lise Lotte; Christensen, Mikkel

    2014-01-01

    INTRODUCTION: Sodium-glucose co-transporter 2 inhibitors (SGLT-2i) increase urinary glucose excretion through a reduced renal glucose reabsorption. We plan to perform a systematic review of SGLT-2i for treatment of type 2 diabetes. METHODS AND ANALYSIS: A systematic review with meta-analyses of r......INTRODUCTION: Sodium-glucose co-transporter 2 inhibitors (SGLT-2i) increase urinary glucose excretion through a reduced renal glucose reabsorption. We plan to perform a systematic review of SGLT-2i for treatment of type 2 diabetes. METHODS AND ANALYSIS: A systematic review with meta......-analyses of randomised clinical trials on SGLT-2i versus placebo, other oral glucose lowering drugs or insulin for patients with type 2 diabetes will be performed. The primary end point will be the glycated haemoglobin. Secondary end points will include changes in body weight, body mass index, fasting plasma glucose......, plasma cholesterol, kidney and liver blood tests, blood pressure and adverse events. Electronic (the Cochrane Library, MEDLINE, EMBASE and the Science Citation Index) and manual searches will be performed. Meta-analyses will be performed and the results presented as mean differences for continuous...

  12. Reinventing the Wheel: The Economic Benefits of Wheeled Transportation in Early British Colonial West Africa

    OpenAIRE

    Isaías N. Chaves; Stanley L. Engerman; James A. Robinson

    2013-01-01

    One of the great puzzles of Sub-Saharan African economic history is that wheeled transportation was barely used prior to the colonial period. Instead, head porterage was the main method of transportation. The consensus among historians is that this was a rational adaption to the underlying conditions and factor endowments. In this paper we undertake the first systematic investigation of the relative costs of the different forms of wheeled transportation in Africa. We focus on calculating the ...

  13. Transport of radioactive materials

    International Nuclear Information System (INIS)

    Huck, W.

    1992-01-01

    The book presents a systematic survey of the legal provisions governing the transport of radioactive materials, placing emphasis on the nuclear licensing provisions of sections 4, 4b of the Atomic Energy, Act (AtG) and sections 8-10 of the Radiation Protection Ordinance (StrlSchV), also considering the provisions of the traffic law governing the carriage of hazardous goods. The author's goal is to establish a systematic basis by comparative analysis of the licensing regulations under atomic energy law, for the purpose of formulating a proposed amendment to the law, for the sake of clarity. The author furthermore looks for and develops criteria that can be of help in distinguishing the regulations governing the carriage of hazardous goods from the nuclear regulatory provisions. He also examines whether such a differentiation is detectable, particularly in those amendments to the StrlSchV which came after the Act on Carriage of Hazardous Goods. The regulations governing the transport of radioactive materials under the AtG meet with the problem of different classification systems being applied, to radioactive materials in the supervisory regulations on the one hand, and to nuclear materials in Annex 1 to the AtG on the other hand. A classification of natural, non-nuclear grade uranium e.g. by the financial security provisions is difficult as a result of these differences in the laws. The author shows that the transport regulations of the StrlSchV represent an isolated supervisory instrument that has no connecting factor to the sections 28 ff StrlSchV, as radiation protection is provided for by the regulations of the Act on Carriage of Hazardous Goods. The author suggests an amendment of existing law incorporating the legal intent of sections 8-10 StrlSchV and of sections 4, 4b AtG into two sections, and abolishing the supervisory provisions of the StrlSchV altogether. (orig./HP) [de

  14. Policy Incentives and the Extension of Mortgage Credit: Increasing Market Discipline for Subprime Lending

    Science.gov (United States)

    An, Xudong; Bostic, Raphael W.

    2009-01-01

    The lax underwriting in non-prime mortgage markets is widely perceived as one cause of the recent difficulties in the housing market. Policymakers are currently considering moves such as enforcing more careful underwriting to provide additional discipline to mortgage markets. This research explores the possibility of another approach to supplement…

  15. Nonequilibrium Green function techniques applied to hot electron quantum transport

    International Nuclear Information System (INIS)

    Jauho, A.P.

    1989-01-01

    During the last few years considerable effort has been devoted to deriving quantum transport equations for semiconductors under extreme conditions (high electric fields, spatial quantization in one or two directions). Here we review the results obtained with nonequilibrium Green function techniques as formulated by Baym and Kadanoff, or by Keldysh. In particular, the following topics will be discussed: (i) Systematic approaches to reduce the transport equation governing the correlation function to a transport equation for the Wigner function; (ii) Approximations reducing the nonmarkovian quantum transport equation to a numerically tractable form, and results for model semiconductors; (iii) Recent progress in extending the formalism to inhomogeneous systems; and (iv) Nonequilibrium screening. In all sections we try to direct the reader's attention to points where the present understanding is (at best) incomplete, and indicate possible lines for future work. (orig.)

  16. Direct measurement of superdiffusive energy transport in disordered granular chains.

    Science.gov (United States)

    Kim, Eunho; Martínez, Alejandro J; Phenisee, Sean E; Kevrekidis, P G; Porter, Mason A; Yang, Jinkyu

    2018-02-13

    Energy transport properties in heterogeneous materials have attracted scientific interest for more than half of a century, and they continue to offer fundamental and rich questions. One of the outstanding challenges is to extend Anderson theory for uncorrelated and fully disordered lattices in condensed-matter systems to physical settings in which additional effects compete with disorder. Here we present the first systematic experimental study of energy transport and localization properties in simultaneously disordered and nonlinear granular crystals. In line with prior theoretical studies, we observe in our experiments that disorder and nonlinearity-which individually favor energy localization-can effectively cancel each other out, resulting in the destruction of wave localization. We also show that the combined effect of disorder and nonlinearity can enable manipulation of energy transport speed in granular crystals. Specifically, we experimentally demonstrate superdiffusive transport. Furthermore, our numerical computations suggest that subdiffusive transport should be attainable by controlling the strength of the system's external precompression force.

  17. Utilisation of helicopter emergency medical services in the early medical response to major incidents: a systematic literature review.

    Science.gov (United States)

    Johnsen, Anne Siri; Fattah, Sabina; Sollid, Stephen J M; Rehn, Marius

    2016-02-09

    This systematic review identifies, describes and appraises the literature describing the utilisation of helicopter emergency medical services (HEMS) in the early medical response to major incidents. Early prehospital phase of a major incident. Systematic literature review performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, the Web of Science, PsycINFO, Scopus, Cinahl, Bibsys Ask, Norart, Svemed and UpToDate were searched using phrases that combined HEMS and 'major incidents' to identify when and how HEMS was utilised. The identified studies were subjected to data extraction and appraisal. The database search identified 4948 articles. Based on the title and abstract, the full text of 96 articles was obtained; of these, 37 articles were included in the review, and an additional five were identified by searching the reference lists of the 37 articles. HEMS was used to transport medical and rescue personnel to the incident and to transport patients to the hospital, especially when the infrastructure was damaged. Insufficient air traffic control, weather conditions, inadequate landing sites and failing communication were described as challenging in some incidents. HEMS was used mainly for patient treatment and to transport patients, personnel and equipment in the early medical management of major incidents, but the optimal utilisation of this specialised resource remains unclear. This review identified operational areas with improvement potential. A lack of systematic indexing, heterogeneous data reporting and weak methodological design, complicated the identification and comparison of incidents, and more systematic reporting is needed. CRD42013004473. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  18. Quality of systematic reviews in pediatric oncology--a systematic review.

    Science.gov (United States)

    Lundh, Andreas; Knijnenburg, Sebastiaan L; Jørgensen, Anders W; van Dalen, Elvira C; Kremer, Leontien C M

    2009-12-01

    To ensure evidence-based decision making in pediatric oncology systematic reviews are necessary. The objective of our study was to evaluate the methodological quality of all currently existing systematic reviews in pediatric oncology. We identified eligible systematic reviews through a systematic search of the literature. Data on clinical and methodological characteristics of the included systematic reviews were extracted. The methodological quality of the included systematic reviews was assessed using the overview quality assessment questionnaire, a validated 10-item quality assessment tool. We compared the methodological quality of systematic reviews published in regular journals with that of Cochrane systematic reviews. We included 117 systematic reviews, 99 systematic reviews published in regular journals and 18 Cochrane systematic reviews. The average methodological quality of systematic reviews was low for all ten items, but the quality of Cochrane systematic reviews was significantly higher than systematic reviews published in regular journals. On a 1-7 scale, the median overall quality score for all systematic reviews was 2 (range 1-7), with a score of 1 (range 1-7) for systematic reviews in regular journals compared to 6 (range 3-7) in Cochrane systematic reviews (pmethodological flaws leading to a high risk of bias. While Cochrane systematic reviews were of higher methodological quality than systematic reviews in regular journals, some of them also had methodological problems. Therefore, the methodology of each individual systematic review should be scrutinized before accepting its results.

  19. Transport processes in space physics and astrophysics

    CERN Document Server

    Zank, Gary P

    2014-01-01

    Transport Processes in Space Physics and Astrophysics' is aimed at graduate level students to provide the necessary mathematical and physics background to understand the transport of gases, charged particle gases, energetic charged particles, turbulence, and radiation in an astrophysical and space physics context. Subjects emphasized in the work include collisional and collisionless processes in gases (neutral or plasma), analogous processes in turbulence fields and radiation fields, and allows for a simplified treatment of the statistical description of the system. A systematic study that addresses the common tools at a graduate level allows students to progress to a point where they can begin their research in a variety of fields within space physics and astrophysics. This book is for graduate students who expect to complete their research in an area of plasma space physics or plasma astrophysics. By providing a broad synthesis in several areas of transport theory and modeling, the work also benefits resear...

  20. A systematic study of wave conditions and sediment transport near Mormugao harbour

    Digital Repository Service at National Institute of Oceanography (India)

    Reddy, M.P.M.

    Wave conditions and the nature of sediment transport in the Mormugao Harbour area have been evaluated in view of the proposed development project of this harbour It has been found from this study that generally high waves will be experienced...

  1. Discrete nodal integral transport-theory method for multidimensional reactor physics and shielding calculations

    International Nuclear Information System (INIS)

    Lawrence, R.D.; Dorning, J.J.

    1980-01-01

    A coarse-mesh discrete nodal integral transport theory method has been developed for the efficient numerical solution of multidimensional transport problems of interest in reactor physics and shielding applications. The method, which is the discrete transport theory analogue and logical extension of the nodal Green's function method previously developed for multidimensional neutron diffusion problems, utilizes the same transverse integration procedure to reduce the multidimensional equations to coupled one-dimensional equations. This is followed by the conversion of the differential equations to local, one-dimensional, in-node integral equations by integrating back along neutron flight paths. One-dimensional and two-dimensional transport theory test problems have been systematically studied to verify the superior computational efficiency of the new method

  2. Quality assurance inspections in the transportation packaging supplier industry

    International Nuclear Information System (INIS)

    Jankovich, J.P.

    1991-01-01

    In this paper the quality assurance inspections of the transportation packaging supplier industry, conducted by the U.S. Nuclear Regulatory Commission (NRC) on a routine basis since 1989 are discussed. The term supplier is used to include designers, fabricators, and distributors that hold NRC approved Quality Assurance Programs and Certificates of Compliance for packagings to transport radioactive materials. The objective of the inspections is to provide assurance that transportation packagings are fabricated and procured in accordance with 10 CFR Parts 21 and 71 requirements. The inspections are conducted in a systematic and comprehensive manner, utilizing uniform inspection techniques in order to assure uniformity and comparability. During the April 1989 and May 1991 period approximately 21 inspections were conducted by the Transportation Branch, Office of Nuclear Material Safety and Safeguards of the NRC. The majority of the findings were identified in the areas of quality assurance procedures, control of special processes (e.g. welding, radiography), and maintenance of QA records

  3. Binding proteins enhance specific uptake rate by increasing the substrate-transporter encounter rate.

    Science.gov (United States)

    Bosdriesz, Evert; Magnúsdóttir, Stefanía; Bruggeman, Frank J; Teusink, Bas; Molenaar, Douwe

    2015-06-01

    Microorganisms rely on binding-protein assisted, active transport systems to scavenge for scarce nutrients. Several advantages of using binding proteins in such uptake systems have been proposed. However, a systematic, rigorous and quantitative analysis of the function of binding proteins is lacking. By combining knowledge of selection pressure and physiochemical constraints, we derive kinetic, thermodynamic, and stoichiometric properties of binding-protein dependent transport systems that enable a maximal import activity per amount of transporter. Under the hypothesis that this maximal specific activity of the transport complex is the selection objective, binding protein concentrations should exceed the concentration of both the scarce nutrient and the transporter. This increases the encounter rate of transporter with loaded binding protein at low substrate concentrations, thereby enhancing the affinity and specific uptake rate. These predictions are experimentally testable, and a number of observations confirm them. © 2015 FEBS.

  4. 46 CFR 249.8 - Limitation on risk.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Limitation on risk. 249.8 Section 249.8 Shipping... OPERATORS APPROVAL OF UNDERWRITERS FOR MARINE HULL INSURANCE § 249.8 Limitation on risk. (a) Underwriters may take a line on any single risk in excess of five percent of its Policyholders' Surplus only with...

  5. Test and evaluation of Fern Engineering Company, Incorporated, solar heating and hot water system. [structural design criteria and system effectiveness

    Science.gov (United States)

    1979-01-01

    Tests, test results, examination and evaluation by Underwriters Laboratory, Inc., of a single family solar heating and hot water system consisting of collector, storage, control, transport, and data acquisition are presented. The structural characteristics of the solar flat plate collectors were evaluated according to snow and wind loads indicated in various building codes to determine their suitability for use both Michigan and Pennsylvania where prototype systems were installed. The flame spread classification of the thermal insulation is discussed and the fire tests conducted on components are described. The operation and dielectrics withstand tests of the energy transport module indicate the module is capable of rated air delivery. Tests of the control panel indicate the relay coil temperatures exceed the temperature limits allowed for the insulating materials involved.

  6. Relationship between particle and heat transport in JT-60U plasmas with internal transport barrier

    International Nuclear Information System (INIS)

    Takenaga, H.

    2002-01-01

    Relationship between particle and heat transport in an internal transport barrier (ITB) has been systematically investigated for the first time in reversed shear (RS) and high-β p ELMy H-mode (weak positive shear) plasmas of JT-60U for understanding of compatibility of improved energy confinement and effective particle control such as exhaust of helium ash and reduction in impurity contamination. In the RS plasma, no helium and carbon accumulation inside the ITB is observed even with highly improved energy confinement. In the high-β p plasma, both helium and carbon density profiles are flat. As the ion temperature profile changes from parabolic- to box-type, the helium diffusivity decreases by a factor of about 2 as well as the ion thermal diffusivity in the RS plasma. The measured soft X-ray profile is more peaked than that calculated by assuming the same n AR profile as the n e profile in the Ar injected RS plasma with the box-type profile, suggesting accumulation of Ar inside the ITB. Particle transport is improved with no change of ion temperature in the RS plasma, when density fluctuation is drastically reduced by a pellet injection. (author)

  7. Quality of systematic reviews in pediatric oncology--a systematic review

    DEFF Research Database (Denmark)

    Lundh, Andreas; Knijnenburg, Sebastiaan L; Jørgensen, Anders W

    2009-01-01

    BACKGROUND: To ensure evidence-based decision making in pediatric oncology systematic reviews are necessary. The objective of our study was to evaluate the methodological quality of all currently existing systematic reviews in pediatric oncology. METHODS: We identified eligible systematic reviews...... through a systematic search of the literature. Data on clinical and methodological characteristics of the included systematic reviews were extracted. The methodological quality of the included systematic reviews was assessed using the overview quality assessment questionnaire, a validated 10-item quality...... assessment tool. We compared the methodological quality of systematic reviews published in regular journals with that of Cochrane systematic reviews. RESULTS: We included 117 systematic reviews, 99 systematic reviews published in regular journals and 18 Cochrane systematic reviews. The average methodological...

  8. Transportable Optical Lattice Clock with 7×10^{-17} Uncertainty.

    Science.gov (United States)

    Koller, S B; Grotti, J; Vogt, St; Al-Masoudi, A; Dörscher, S; Häfner, S; Sterr, U; Lisdat, Ch

    2017-02-17

    We present a transportable optical clock (TOC) with ^{87}Sr. Its complete characterization against a stationary lattice clock resulted in a systematic uncertainty of 7.4×10^{-17}, which is currently limited by the statistics of the determination of the residual lattice light shift, and an instability of 1.3×10^{-15}/sqrt[τ] with an averaging time τ in seconds. Measurements confirm that the systematic uncertainty can be reduced to below the design goal of 1×10^{-17}. To our knowledge, these are the best uncertainties and instabilities reported for any transportable clock to date. For autonomous operation, the TOC has been installed in an air-conditioned car trailer. It is suitable for chronometric leveling with submeter resolution as well as for intercontinental cross-linking of optical clocks, which is essential for a redefinition of the International System of Units (SI) second. In addition, the TOC will be used for high precision experiments for fundamental science that are commonly tied to precise frequency measurements and its development is an important step to space-borne optical clocks.

  9. Transportable Optical Lattice Clock with 7 ×10-17 Uncertainty

    Science.gov (United States)

    Koller, S. B.; Grotti, J.; Vogt, St.; Al-Masoudi, A.; Dörscher, S.; Häfner, S.; Sterr, U.; Lisdat, Ch.

    2017-02-01

    We present a transportable optical clock (TOC) with Sr 87 . Its complete characterization against a stationary lattice clock resulted in a systematic uncertainty of 7.4 ×10-17, which is currently limited by the statistics of the determination of the residual lattice light shift, and an instability of 1.3 ×10-15/√{τ } with an averaging time τ in seconds. Measurements confirm that the systematic uncertainty can be reduced to below the design goal of 1 ×10-17. To our knowledge, these are the best uncertainties and instabilities reported for any transportable clock to date. For autonomous operation, the TOC has been installed in an air-conditioned car trailer. It is suitable for chronometric leveling with submeter resolution as well as for intercontinental cross-linking of optical clocks, which is essential for a redefinition of the International System of Units (SI) second. In addition, the TOC will be used for high precision experiments for fundamental science that are commonly tied to precise frequency measurements and its development is an important step to space-borne optical clocks.

  10. Range of validity of transport equations

    International Nuclear Information System (INIS)

    Berges, Juergen; Borsanyi, Szabolcs

    2006-01-01

    Transport equations can be derived from quantum field theory assuming a loss of information about the details of the initial state and a gradient expansion. While the latter can be systematically improved, the assumption about a memory loss is not known to be controlled by a small expansion parameter. We determine the range of validity of transport equations for the example of a scalar g 2 Φ 4 theory. We solve the nonequilibrium time evolution using the three-loop 2PI effective action. The approximation includes off-shell and memory effects and assumes no gradient expansion. This is compared to transport equations to lowest order (LO) and beyond (NLO). We find that the earliest time for the validity of transport equations is set by the characteristic relaxation time scale t damp =-2ω/Σ ρ (eq) , where -Σ ρ (eq) /2 denotes the on-shell imaginary-part of the self-energy. This time scale agrees with the characteristic time for partial memory loss, but is much shorter than thermal equilibration times. For times larger than about t damp the gradient expansion to NLO is found to describe the full results rather well for g 2 (less-or-similar sign)1

  11. Analyzing the influence of ‘knowledge technologies’ in transport planning

    DEFF Research Database (Denmark)

    Gudmundsson, Henrik

    , but models also share with other knowledge technologies the fate of being sometimes used politically, rather than analytically, perhaps even distortively rather than supportively, or not being used at all. The ‘actual’ influence that transport models and other tools exert over planning processes and outcomes...... to characterize and analyze the use and influence of ‘knowledge technologies’ in the transport sector. The paper is not primarily about models per se or particular model applications, but will try to situate simulation models in a wider ‘use and influence’ landscape of transport planning knowledge technologies...... of the paper is thus to seek is to systematize previous research on ‘knowledge use’, discuss its applicability to context of transport policy and planning technologies, and critically reflect on ways to research the use and influence ‘pathways’ of knowledge technologies - such as models - in this sector. • One...

  12. On the Langevin approach to particle transport

    International Nuclear Information System (INIS)

    Bringuier, Eric

    2006-01-01

    In the Langevin description of Brownian motion, the action of the surrounding medium upon the Brownian particle is split up into a systematic friction force of Stokes type and a randomly fluctuating force, alternatively termed noise. That simple description accounts for several basic features of particle transport in a medium, making it attractive to teach at the undergraduate level, but its range of applicability is limited. The limitation is illustrated here by showing that the Langevin description fails to account realistically for the transport of a charged particle in a medium under crossed electric and magnetic fields and the ensuing Hall effect. That particular failure is rooted in the concept of the friction force rather than in the accompanying random force. It is then shown that the framework of kinetic theory offers a better account of the Hall effect. It is concluded that the Langevin description is nothing but an extension of Drude's transport model subsuming diffusion, and so it inherits basic limitations from that model. This paper thus describes the interrelationship of the Langevin approach, the Drude model and kinetic theory, in a specific transport problem of physical interest

  13. Mathematical modeling plasma transport in tokamaks

    Energy Technology Data Exchange (ETDEWEB)

    Quiang, Ji [Univ. of Illinois, Urbana-Champaign, IL (United States)

    1997-01-01

    In this work, the author applied a systematic calibration, validation and application procedure based on the methodology of mathematical modeling to international thermonuclear experimental reactor (ITER) ignition studies. The multi-mode plasma transport model used here includes a linear combination of drift wave branch and ballooning branch instabilities with two a priori uncertain constants to account for anomalous plasma transport in tokamaks. A Bayesian parameter estimation method is used including experimental calibration error/model offsets and error bar rescaling factors to determine the two uncertain constants in the transport model with quantitative confidence level estimates for the calibrated parameters, which gives two saturation levels of instabilities. This method is first tested using a gyroBohm multi-mode transport model with a pair of DIII-D discharge experimental data, and then applied to calibrating a nominal multi-mode transport model against a broad database using twelve discharges from seven different tokamaks. The calibrated transport model is then validated on five discharges from JT-60 with no adjustable constants. The results are in a good agreement with experimental data. Finally, the resulting class of multi-mode tokamak plasma transport models is applied to the transport analysis of the ignition probability in a next generation machine, ITER. A reference simulation of basic ITER engineering design activity (EDA) parameters shows that a self-sustained thermonuclear burn with 1.5 GW output power can be achieved provided that impurity control makes radiative losses sufficiently small at an average plasma density of 1.2 X 1020/m3 with 50 MW auxiliary heating. The ignition probability of ITER for the EDA parameters, can be formally as high as 99.9% in the present context. The same probability for concept design activity (CDA) parameters of ITER, which has smaller size and lower current, is only 62.6%.

  14. Mathematical modeling plasma transport in tokamaks

    International Nuclear Information System (INIS)

    Quiang, Ji

    1995-01-01

    In this work, the author applied a systematic calibration, validation and application procedure based on the methodology of mathematical modeling to international thermonuclear experimental reactor (ITER) ignition studies. The multi-mode plasma transport model used here includes a linear combination of drift wave branch and ballooning branch instabilities with two a priori uncertain constants to account for anomalous plasma transport in tokamaks. A Bayesian parameter estimation method is used including experimental calibration error/model offsets and error bar rescaling factors to determine the two uncertain constants in the transport model with quantitative confidence level estimates for the calibrated parameters, which gives two saturation levels of instabilities. This method is first tested using a gyroBohm multi-mode transport model with a pair of DIII-D discharge experimental data, and then applied to calibrating a nominal multi-mode transport model against a broad database using twelve discharges from seven different tokamaks. The calibrated transport model is then validated on five discharges from JT-60 with no adjustable constants. The results are in a good agreement with experimental data. Finally, the resulting class of multi-mode tokamak plasma transport models is applied to the transport analysis of the ignition probability in a next generation machine, ITER. A reference simulation of basic ITER engineering design activity (EDA) parameters shows that a self-sustained thermonuclear burn with 1.5 GW output power can be achieved provided that impurity control makes radiative losses sufficiently small at an average plasma density of 1.2 X 10 20 /m 3 with 50 MW auxiliary heating. The ignition probability of ITER for the EDA parameters, can be formally as high as 99.9% in the present context. The same probability for concept design activity (CDA) parameters of ITER, which has smaller size and lower current, is only 62.6%

  15. Mass transport thermodynamics in nonisothermal molecular liquid mixtures

    Energy Technology Data Exchange (ETDEWEB)

    Semenov, Semen N [Institute for Biochemical Physics, Russian Academy of Sciences, Moscow (Russian Federation); Schimpf, M E [Department of Chemistry and Biochemistry, Boise State University, Boise, ID (United States)

    2009-10-31

    Mass transport in a nonisothermal binary molecular mixture is systematically discussed in terms of nonequilibrium thermodynamics, which for the first time allows a consistent and unambiguous description of the process. The thermodynamic and hydrodynamic approaches are compared, revealing that nonequilibrium thermodynamics and physicochemical hydrodynamics yield essentially the same results for molecular systems. The applicability limits for the proposed version of the thermodynamic approach are determined for large particles. (methodological notes)

  16. The systematic error of temperature noise correlation measurement method and self-calibration

    International Nuclear Information System (INIS)

    Tian Hong; Tong Yunxian

    1993-04-01

    The turbulent transport behavior of fluid noise and the nature of noise affect on the velocity measurement system have been studied. The systematic error of velocity measurement system is analyzed. A theoretical calibration method is proposed, which makes the velocity measurement of time-correlation as an absolute measurement method. The theoretical results are in good agreement with experiments

  17. Theoretical approaches to determining the financial provision of public transportation

    Directory of Open Access Journals (Sweden)

    O.A. Vygovska

    2018-03-01

    Full Text Available The work is devoted to the improvement of theoretical approaches in determining the financial provision of transportation by public transport at the regional level. The author summarizes the concept of the «financial security» and defines the main difference from the term «financing». The systematization of key differences in the financial provision of a transport company from other financial entities of the economic sector at the national and regional levels is carried out. The disadvantages and advantages of sources of financial support are analyzed. The purpose of the article is to study theoretical approaches in determining the financial provision of transportation by public transport at the regional level. The prospects for further scientific research are the need to identify new scientific approaches and techniques to substantiate and elaborate the concept of the «financial provision of transportation by public transport». The practical application of the research should be formed in a detailed analysis of cash flow streams in the system of «state – regional authority – economic entity». The financial provision of transportation by public transport at the regional level has not been given the sufficient attention in the scientific research within the country. This fact confirms the need for a thorough analysis of the transport industry as a whole.

  18. Heat and damp transport in cavity bricks. Waerme- und Feuchtetransport in Hochlochziegeln

    Energy Technology Data Exchange (ETDEWEB)

    Elsner, M

    1987-11-19

    The aim of this work is a systematic measurement of the structural effect of cavity bricks on the thermal insulation and thermal storage values depending on the material values of the bricks and the mortar. The arrangement and orientation of the hollow spaces and their dimensions should be varied. Brick shapes with socalled handle slots, which give more convenient handling, and with mortar pockets instead of mortar gaps, should be taken into account in the investigation. Special attention should be paid to the heat transport mechanism in the hollow spaces, where thermal conduction, thermal radiation and convection heat transport are superimposed on one another. The second main aim of the work is the calculation of the coupled heat and damp transport in hollow bricks. The heat and damp transport is described by a coupled system of differential equations, where the decisive transport coefficients should be shown as a function of the variables determining the transport processes. (orig./MM).

  19. Comparison of low confinement mode transport simulations using the mixed Bohm/gyro-Bohm and the Multi-Mode-95 transport model

    International Nuclear Information System (INIS)

    Onjun, Thawatchai; Bateman, Glenn; Kritz, Arnold H.; Hannum, David

    2001-01-01

    Predictive transport simulations using the mixed Bohm/gyro-Bohm (JET) transport model [M. Erba , Plasma Phys. Controlled Fusion 39, 261 (1997)] are compared with simulations using the Multi-Mode-95 (MMM95) transport model [G. Bateman , Phys. Plasmas 5, 1793 (1998)]. Temperature and density profiles from these simulations are compared with experimental data for 13 low confinement mode (L-mode) discharges from the Doublet III-D Tokamak (DIII-D) [J. L. Luxon and L. G. Davis, Fusion Technol. 8, 441 (1985)] and the Tokamak Fusion Test Reactor (TFTR) [D. Grove and D. M. Meade, Nucl. Fusion 25, 1167 (1985)]. The selected discharges include systematic scans over gyro-radius, plasma power, current, and density. It is found that simulations using the two models match experimental data equally well, in spite of the fact that the JET model has predominantly Bohm scaling (proportional to gyro-radius) while the MMM95 model has a purely gyro-Bohm scaling (proportional to gyro-radius squared)

  20. Systematic and reliable multiscale modelling of lithium batteries

    Science.gov (United States)

    Atalay, Selcuk; Schmuck, Markus

    2017-11-01

    Motivated by the increasing interest in lithium batteries as energy storage devices (e.g. cars/bycicles/public transport, social robot companions, mobile phones, and tablets), we investigate three basic cells: (i) a single intercalation host; (ii) a periodic arrangement of intercalation hosts; and (iii) a rigorously upscaled formulation of (ii) as initiated in. By systematically accounting for Li transport and interfacial reactions in (i)-(iii), we compute the associated chracteristic current-voltage curves and power densities. Finally, we discuss the influence of how the intercalation particles are arranged. Our findings are expected to improve the understanding of how microscopic properties affect the battery behaviour observed on the macroscale and at the same time, the upscaled formulation (iii) serves as an efficient computational tool. This work has been supported by EPSRC, UK, through the Grant No. EP/P011713/1.

  1. Enhancing the design of in situ chemical barriers with multicomponent reactive transport modeling

    International Nuclear Information System (INIS)

    Sevougian, S.D.; Steefel, C.I.; Yabusaki, S.B.

    1994-11-01

    This paper addresses the need for systematic control of field-scale performance in the emplacement and operation of in situ chemical treatment barriers; in particular, it addresses the issue of how the local coupling of reaction kinetics and material heterogeneities at the laboratory or bench scale can be accurately upscaled to the field. The authors have recently developed modeling analysis tools that can explicitly account for all relevant chemical reactions that accompany the transport of reagents and contaminants through a chemically and physically heterogeneous subsurface rock or soil matrix. These tools are incorporated into an enhanced design methodology for in situ chemical treatment technologies, and the new methodology is demonstrated in the ongoing design of a field experiment for the In Situ Redox Manipulation (ISRM) project at the U.S. Department of Energy (DOE) Hanford Site. The ISRM design approach, which systematically integrates bench-scale and site characterization information, provides an ideal test for the new reactive transport techniques. The need for the enhanced chemistry capability is demonstrated by an example that shows how intra-aqueous redox kinetics can affect the transport of reactive solutes. Simulations are carried out on massively parallel computer architectures to resolve the influence of multiscale heterogeneities on multicomponent, multidimensional reactive transport. The technology will soon be available to design larger-scale remediation schemes

  2. Fostering child-centred approaches to transport research, planning and policy development: a pilot methodology

    CSIR Research Space (South Africa)

    Mashiri, M

    2007-01-01

    Full Text Available countries, this is a surprising oversight. Much of our knowledge of children and transport is gleaned from observation and anecdotal evidence. There has been little systematic study of the issues. Children are not seriously considered stakeholders...

  3. Two decades' experience with interfacility transport on extracorporeal membrane oxygenation.

    Science.gov (United States)

    Bryner, Benjamin; Cooley, Elaine; Copenhaver, William; Brierley, Kristin; Teman, Nicholas; Landis, Denise; Rycus, Peter; Hemmila, Mark; Napolitano, Lena M; Haft, Jonathan; Park, Pauline K; Bartlett, Robert H

    2014-10-01

    Interfacility transport of patients on extracorporeal membrane oxygenation (ECMO) has been performed in large numbers at only a few programs. Limited data are available on outcomes after ECMO transport to justify expanding or discontinuing these programs. This was a retrospective review of a 20-year, single-institution experience with interhospital ECMO transport as well as a systematic review of reports of transfers of patients on ECMO. Results of both were compared with historical data from the international registry of the Extracorporeal Life Support Organization (ELSO). Between 1990 and 2012, ECMO was used to facilitate transport of 221 patients to our institution, and 135 (62%) survived to discharge. Review of an additional 27 case series describing ECMO transport of 643 patients showed an overall survival of 61%. After stratifying by age and primary indication for ECMO, survival of transported patients was not significantly different compared with all ECMO patients in the ELSO registry, with the exception of pediatric patients treated for respiratory failure (transported patients in this category had higher survival than those in the ELSO registry). Interfacility transport on ECMO is feasible and can be accomplished safely in the critically ill. Survival of transported patients is comparable to age-matched and treatment-matched ECMO patients at large. Copyright © 2014 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  4. Flux-based transport enhancement as a plausible unifying mechanism for auxin transport in meristem development.

    Directory of Open Access Journals (Sweden)

    Szymon Stoma

    2008-10-01

    Full Text Available Plants continuously generate new organs through the activity of populations of stem cells called meristems. The shoot apical meristem initiates leaves, flowers, and lateral meristems in highly ordered, spiralled, or whorled patterns via a process called phyllotaxis. It is commonly accepted that the active transport of the plant hormone auxin plays a major role in this process. Current hypotheses propose that cellular hormone transporters of the PIN family would create local auxin maxima at precise positions, which in turn would lead to organ initiation. To explain how auxin transporters could create hormone fluxes to distinct regions within the plant, different concepts have been proposed. A major hypothesis, canalization, proposes that the auxin transporters act by amplifying and stabilizing existing fluxes, which could be initiated, for example, by local diffusion. This convincingly explains the organised auxin fluxes during vein formation, but for the shoot apical meristem a second hypothesis was proposed, where the hormone would be systematically transported towards the areas with the highest concentrations. This implies the coexistence of two radically different mechanisms for PIN allocation in the membrane, one based on flux sensing and the other on local concentration sensing. Because these patterning processes require the interaction of hundreds of cells, it is impossible to estimate on a purely intuitive basis if a particular scenario is plausible or not. Therefore, computational modelling provides a powerful means to test this type of complex hypothesis. Here, using a dedicated computer simulation tool, we show that a flux-based polarization hypothesis is able to explain auxin transport at the shoot meristem as well, thus providing a unifying concept for the control of auxin distribution in the plant. Further experiments are now required to distinguish between flux-based polarization and other hypotheses.

  5. Charge transport in conjugated polymers: a multiscale picture

    Science.gov (United States)

    Ruehle, Victor; Kirkpatrick, James; Kremer, Kurt; Andrienko, Denis

    2009-03-01

    A framework to study charge transport in conjugated polymers using realistic morphologies is developed. First, the atomistic force field is refined using first-principles calculations. Systematic coarse graining is then performed to extend simulation times and system sizes accessible to molecular dynamics simulations. Material morphologies are generated using the coarse grained and atomistic models. Finally, the charge mobility is obtained using temperature activated hopping picture for charge transport [1]. The framework is tested on neutral and oxidized polypyrrole with different structural ordering [2]. [4pt] [1] J. Kirkpatrick, V. Marcon, J. Nelson, K. Kremer, D. Andrienko, Phys. Rev. Lett. 98, 227402 (2007)[0pt] [2] V. Ruehle, J. Kirkpatrick, K. Kremer, D. Andrienko, Phys. Stat. Solidi B, 245, 844 (2008)

  6. Reducing transport costs and improving sustainability simultaneously through horizontal logistics collaboration: a case study

    OpenAIRE

    Van Lier, Tom; Macharis, Cathy; Caris, An; Vrenken, Huub

    2010-01-01

    In this paper the potential of a more systematic bundling of the outbound freight flows out of three neighboring distribution centers (DCs) of the same company, each specialized in a specific product category and each using a separate planning system, is investigated. Most of the outbound flows are currently still transported by truck, so one way to simultaneously achieve lower transport costs and more sustainable logistics is through supply chain collaboration in outbound logistics. This pap...

  7. A high mitochondrial transport rate characterizes CNS neurons with high axonal regeneration capacity.

    Directory of Open Access Journals (Sweden)

    Romain Cartoni

    Full Text Available Improving axonal transport in the injured and diseased central nervous system has been proposed as a promising strategy to improve neuronal repair. However, the contribution of each cargo to the repair mechanism is unknown. DRG neurons globally increase axonal transport during regeneration. Because the transport of specific cargos after axonal insult has not been examined systematically in a model of enhanced regenerative capacity, it is unknown whether the transport of all cargos would be modulated equally in injured central nervous system neurons. Here, using a microfluidic culture system we compared neurons co-deleted for PTEN and SOCS3, an established model of high axonal regeneration capacity, to control neurons. We measured the axonal transport of three cargos (mitochondria, synaptic vesicles and late endosomes in regenerating axons and found that the transport of mitochondria, but not the other cargos, was increased in PTEN/SOCS3 co-deleted axons relative to controls. The results reported here suggest a pivotal role for this organelle during axonal regeneration.

  8. Transport lattice models of heat transport in skin with spatially heterogeneous, temperature-dependent perfusion

    Directory of Open Access Journals (Sweden)

    Martin Gregory T

    2004-11-01

    skin was solved by exploiting the mathematical analogy between local thermal models and local electrical (charge transport models, thereby allowing robust, circuit simulation software to obtain solutions to Kirchhoff's laws for the system model. Transport lattices allow systematic introduction of realistic geometry and spatially heterogeneous heat transport mechanisms. Local representations for both simple, passive functions and more complex local models can be easily and intuitively included into the system model of a tissue.

  9. Systematic trends in the design and study of new organic conductors

    International Nuclear Information System (INIS)

    Cowan, D.O.; Bailey, A.B.; Duan, H.; Fortkort, J.A.; Liu, C.Y.; Mays, M.D.; McCullough, R.D.; Bryden, W.A.; Poehler, T.O.; Kistenmacher, T.J.

    1989-01-01

    The recent synthesis of tetratellurafulvalene (TTeF) makes it possible to examine in a more systematic fashion how structural modification affect the ionization potential, polarizability, on-site Coulomb repulsion, bandwidths (in sack dp-π orbital overlap), dimensionality (between stack dp-π and σ orbital overlap) and how these factors influence the electrical transport and magnetic susceptibility of mixed valence salts derived from sulfur, selenium, and tellurium π-donors

  10. Can lignocellulosic hydrocarbon liquids rival lignocellulose-derived ethanol as a future transport fuel?

    Directory of Open Access Journals (Sweden)

    Yao Ding

    2012-11-01

    Full Text Available Although transport fuels are currently obtained mainly from petroleum, alternative fuels derived from lignocellulosic biomass (LB have drawn much attention in recent years in light of the limited reserves of crude oil and the associated environmental issues. Lignocellulosic ethanol (LE and lignocellulosic hydrocarbons (LH are two typical representatives of the LB-derived transport fuels. This editorial systematically compares LE and LB from production to their application in transport fuels. It can be demonstrated that LH has many advantages over LE relative to such uses. However, most recent studies on the production of the LB-derived transport fuels have focused on LE production. Hence, it is strongly recommended that more research should be aimed at developing an efficient and economically viable process for industrial LH production.

  11. Comparison of diffusion and transport theory analysis with experimental results in fast breeder test reactor

    International Nuclear Information System (INIS)

    Sathyabama, N.; Mohanakrishnan, P.; Lee, S.M.

    1994-01-01

    A systematic analysis has been performed by 3 dimensional diffusion and transport methods to calculate the measured control rod worths and subassembly wise power distribution in fast breeder test reactor. Geometry corrections (rectangular to hexagonal and diffusion to transport corrections are estimated for multiplication factors and control rod worths. Calculated control rod worths by diffusion and transport theory are nearly the same and 10% above measured values. Power distribution in the core periphery is over predicted (15%) by diffusion theory. But, this over prediction reduces to 8% by use of the S N method. (authors). 9 refs., 4 tabs., 3 fig

  12. Bounded rational choice behaviour: applications in transport

    DEFF Research Database (Denmark)

    Jensen, Anders Fjendbo

    2016-01-01

    Even though the theory of rational behaviour has been challenged for almost 100 years, the dominant approach within the field of transport has been based upon the assumptions of neoclassical economics that we live in a world of rational decision makers who always have perfect knowledge and aim...... rational choice behaviour focuses on how the latter approach can be seriously taken into account within transport applications. As the editors discuss in the introduction, a true optimal choice can only be made if an individual has full and perfect information of all relevant attributes in his/her choice...... set. An individual is said to demonstrate bounded rational behaviour if he/she does not systematically consider all attributes deemed relevant for the decision problem at hand, does not consider all choice options and/or does not choose the best choice alternative. Such simplified representation...

  13. Access to and use of infertility services in the United States: framing the challenges.

    Science.gov (United States)

    Adashi, Eli Y; Dean, Laura A

    2016-05-01

    An overview of access to and use of general infertility and assisted reproductive technology (ART) services in the United States (U.S.) shows a declining trend for the ever-use of infertility services. Moreover, the use of ART services lags relative to other member nations of the Organization for Economic Co-operation and Development (OECD). Access to and use of general infertility and ART services is primarily undermined by a severely constrained underwriting universe dominated by self-insured employers and by a finite number of state infertility insurance mandates. The contribution of traditional public and private payers to the underwriting of ART is limited. As compared with OECD member nations wherein the access to and underwriting of general infertility and ART services is universal, the current status quo in the U.S. can only be characterized as dismal. Further, the current state of affairs is socially unjust in that the right to build a family in the face of infertility appears to have become a function of economic prowess. Given the dominance of the self-insured employers as underwriters of general infertility and ART services, advocacy directed at this interest group is likely to prove most productive. Improving the state of underwriting of general infertility and ART services in the U.S. must be embraced as a central moral imperative and as an unwavering strategic goal of the professional societies entrusted with the reproductive health of women and men. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  14. A Systematic Transport and Thermodynamic Study of Heavy Transition Metal Oxides with Hexagonal Structure

    Science.gov (United States)

    Butrouna, Kamal

    There is no apparent, dominant interaction in heavy transition metal oxides (TMO), especially in 5d-TMO, where all relevant interactions are of comparable energy scales, and therefore strongly compete. In particular, the spin-orbit interaction (SOI) strongly competes with the electron-lattice and on-site Coulomb interaction (U). Therefore, any tool that allows one to tune the relative strengths of SOI and U is expected to offer an opportunity for the discovery and study of novel materials. BaIrO3 is a magnetic insulator driven by SOI, whereas the isostructural BaRuO3 is a paramagnetic metal. The contrasting ground states have been shown to result from the critical role of SOI in the iridate. This dissertation thoroughly examines a wide array of newly observed novel phenomena induced by adjusting the relative strengths of SOI and U via a systematic chemical substitution of the Ru4+(4d 4) ions for Ir4+(5d5) ions in BaIrO3, i.e., in high quality single crystals of BaIr1--x RuxO3(0.0 ≤ x ≤ 1.0). Our investigation of structural, magnetic, transport and thermal properties reveals that Ru substitution directly rebalances the competing energies so profoundly that it generates a rich phase diagram for BaIr 1--xRuxO 3 featuring two major effects: (1) Light Ru doping (0 ≤ x ≤ 0.15) prompts a simultaneous and precipitous drop in both the magnetic ordering temperature TC and the electrical resistivity, which exhibits metal-insulator transition at around TC. (2) Heavier Ru doping (0.41 ≤ x ≤ 0.82) induces a robust metallic and spin frustration state. For comparison and contrast, we also substituted Rh4+(4d 5) ions for Ir4+(5d5) ions in BaIrO3, i.e. in BaIr1--xRhxO 3(0.0 ≤ x ≤ 0.1), where Rh only reduces the SOI, but without altering the band filling. Hence, this system remains tuned at the Mott instability and is very susceptible to disorder scattering which gives rise to Anderson localization. KEYWORDS: spin-orbit interaction, heavy transition metal oxides

  15. Modeling in transport phenomena a conceptual approach

    CERN Document Server

    Tosun, Ismail

    2007-01-01

    Modeling in Transport Phenomena, Second Edition presents and clearly explains with example problems the basic concepts and their applications to fluid flow, heat transfer, mass transfer, chemical reaction engineering and thermodynamics. A balanced approach is presented between analysis and synthesis, students will understand how to use the solution in engineering analysis. Systematic derivations of the equations and the physical significance of each term are given in detail, for students to easily understand and follow up the material. There is a strong incentive in science and engineering to

  16. Dissemination bias in systematic reviews of animal research: a systematic review.

    Directory of Open Access Journals (Sweden)

    Katharina F Mueller

    Full Text Available Systematic reviews of preclinical studies, in vivo animal experiments in particular, can influence clinical research and thus even clinical care. Dissemination bias, selective dissemination of positive or significant results, is one of the major threats to validity in systematic reviews also in the realm of animal studies. We conducted a systematic review to determine the number of published systematic reviews of animal studies until present, to investigate their methodological features especially with respect to assessment of dissemination bias, and to investigate the citation of preclinical systematic reviews on clinical research.Eligible studies for this systematic review constitute systematic reviews that summarize in vivo animal experiments whose results could be interpreted as applicable to clinical care. We systematically searched Ovid Medline, Embase, ToxNet, and ScienceDirect from 1st January 2009 to 9th January 2013 for eligible systematic reviews without language restrictions. Furthermore we included articles from two previous systematic reviews by Peters et al. and Korevaar et al.The literature search and screening process resulted in 512 included full text articles. We found an increasing number of published preclinical systematic reviews over time. The methodological quality of preclinical systematic reviews was low. The majority of preclinical systematic reviews did not assess methodological quality of the included studies (71%, nor did they assess heterogeneity (81% or dissemination bias (87%. Statistics quantifying the importance of clinical research citing systematic reviews of animal studies showed that clinical studies referred to the preclinical research mainly to justify their study or a future study (76%.Preclinical systematic reviews may have an influence on clinical research but their methodological quality frequently remains low. Therefore, systematic reviews of animal research should be critically appraised before

  17. Commercial Consolidation Model Applied to Transport Infrastructure

    Energy Technology Data Exchange (ETDEWEB)

    Guilherme de Aragão, J.J.; Santos Fontes Pereira, L. dos; Yamashita, Y.

    2016-07-01

    Since the 1990s, transport concessions, including public-private partnerships (PPPs), have been increasingly adopted by governments as an alternative for financing and operations in public investments, especially in transport infrastructure. The advantage pointed out by proponents of these models lies in merging the expertise and capital of the private sector to the public interest. Several arrangements are possible and have been employed in different cases. After the duration of the first PPP contracts in transportation, many authors have analyzed the success and failure factors of partnerships. The occurrence of failures in some stages of the process can greatly encumber the public administration, incurring losses to the fiscal responsibility of the competent bodies. This article aims to propose a new commercial consolidation model applied to transport infrastructure to ensure fiscal sustainability and overcome the weaknesses of current models. Initially, a systematic review of the literature covering studies on transport concessions between 1990 and 2015 is offered, where the different approaches between various countries are compared and the critical success factors indicated in the studies are identified. In the subsequent part of the paper, an approach for the commercial consolidation of the infrastructure concessions is presented, where the concessionary is paid following a finalistic performance model, which includes the overall fiscal balance of regional growth. Finally, the papers analyses the usefulness of the model in coping with the critical success factors explained before. (Author)

  18. Modeling the fate transport of cesium in crushed granite

    International Nuclear Information System (INIS)

    Lee, C.B.; Kuo, Y.M.; Hsu, C.N.; Li, M.H.; Cheng, H.P.; Teng, S.P.

    2005-01-01

    Full text of publication follows: In order to assess the safety of a underground radwaste repository, reactive transport models suitable for evaluating the fate and transport of radionuclides need to be established based on experimental observation and analysis. The goal of this study is to construct adequate models simulating the reactive transport of cesium (Cs) in crushed granite through a systematic analysis, where synthetic groundwater (SGW) and synthetic seawater (SSW) were employed as the liquid phase. To build such models, this study applied N 2 -BET, x-ray diffraction (XRD), polar-microscopy/ auto-radiography, and solid-phase digestion for the analysis of granite, kinetic batch tests for the characterization of sorption/desorption of Cs, and multi-stage advection-dispersion column tests for the determination of major transport processes and the calibration/validation of hypothesized reactive transport models. Based on the results of solid phase analysis and batch tests, a two-site Langmuir kinetic model has been determined capable of appropriately describing Cs sorption/desorption under test conditions. From the results of non-reactive HTO column tests, a mobile/immobile transport model was proposed to capture the major transport processes in our column system. However, the combination of the two-site Langmuir model and the mobile/immobile transport model failed to provide numerical breakthrough curves matching the Cs experimental breakthroughs. It implied that our model needs to be further refined. To achieve this, the setup of our column test needs to be modified first to reduce the volume of column connecting space, so that the effect of extra diffusion/dispersion on breakthroughs would be minimized and major transport characteristics can be clearly revealed. Moreover, more investigations on the reaction mechanisms and transport processes of the reactive transport system must be conducted. (authors)

  19. Dynamics of intermodal logistical systems on containerisation and road transportation in Durban, South Africa

    Directory of Open Access Journals (Sweden)

    Nerissa Govender

    2014-12-01

    Full Text Available The underlying port operations in Durban, South Africa, epitomise intense global competitiveness in the intermodal logistics chain. The link between containerisation and theroad transport network can falter as a result of the dynamics of the logistics system. The main objective of the study was to establish the extent of the intermodal challenges of logistical systems on containerisation to which the role of intermodal sea–road freight transportation enhances the logistical competitiveness. It further examined the intermodal relationship on containerised freight between the challenges of containerisation processes and the effects on road freight transport mode. The impact of containerisation on intermodalism, the sea–road freight transport network and the technological attributes of security-based systems and logistical tracking protocols influence the systematic movement of containers on Durban’s public roads.

  20. Carbon Footprint Linked to transport infrastructures; La huella de carbono en las infraestructuras de transporte

    Energy Technology Data Exchange (ETDEWEB)

    Crespo Garcia, L.; Jimenez Arroyo, F.

    2013-06-01

    Quantification of emissions of greenhouse effect gases associated to transport infrastructures has been addressed in different ways. The first tools for this purpose appeared with the application of ISO 14040 standards (Life cycle analysis) that, applied to the particular case of energetic resources, led to a new concept known as carbon footprint. There is a specific standard for this quantification (ISO 14064) according to which, for the case of infrastructures, emissions and environmental effects linked to the whole life cycle are assessed taking into account all the stages: building, exploitation, maintenance and dismantling. the key point to perform this analysis is the accurate definition of a calculation methodology to be applied to the inventory of activities covered, in order to avoid information lacks, overlaps or redundancies. Quantification tools for emissions are effectively a reality, but social and political will, supported by strong economical reasons recognizing energy as a vital resource, is necessary for these tools to be developed, enhanced and used in a systematic way as a key decision element to choice among different transport alternatives. (Author) 23 refs.

  1. Generalized diffusion theory for calculating the neutron transport scalar flux

    International Nuclear Information System (INIS)

    Alcouffe, R.E.

    1975-01-01

    A generalization of the neutron diffusion equation is introduced, the solution of which is an accurate approximation to the transport scalar flux. In this generalization the auxiliary transport calculations of the system of interest are utilized to compute an accurate, pointwise diffusion coefficient. A procedure is specified to generate and improve this auxiliary information in a systematic way, leading to improvement in the calculated diffusion scalar flux. This improvement is shown to be contingent upon satisfying the condition of positive calculated-diffusion coefficients, and an algorithm that ensures this positivity is presented. The generalized diffusion theory is also shown to be compatible with conventional diffusion theory in the sense that the same methods and codes can be used to calculate a solution for both. The accuracy of the method compared to reference S/sub N/ transport calculations is demonstrated for a wide variety of examples. (U.S.)

  2. Transport-induced shifts in condensate dew-point and composition in multicomponent systems with chemical reaction

    Science.gov (United States)

    Rosner, D. E.; Nagarajan, R.

    1985-01-01

    Partial heterogeneous condensation phenomena in multicomponent reacting systems are analyzed taking into consideration the chemical element transport phenomena. It is demonstrated that the dew-point surface temperature in chemically reactive systems is not a purely thermodynamic quantity, but is influenced by the multicomponent diffusion and Soret-mass diffusion phenomena. Several distinct dew-points are shown to exist in such systems and, as a result of transport constraints, the 'sharp' locus between two chemically distinct condensates is systematically moved to a difference mainstream composition.

  3. Transport Statistics - Transport - UNECE

    Science.gov (United States)

    Sustainable Energy Statistics Trade Transport Themes UNECE and the SDGs Climate Change Gender Ideas 4 Change UNECE Weekly Videos UNECE Transport Areas of Work Transport Statistics Transport Transport Statistics About us Terms of Reference Meetings and Events Meetings Working Party on Transport Statistics (WP.6

  4. Analytic approach to auroral electron transport and energy degradation

    International Nuclear Information System (INIS)

    Stamnes, K.

    1980-01-01

    The interaction of a beam of auroral electrons with the atmosphere is described by the linear transport equation, encompassing discrete energy loss, multiple scattering, and secondary electrons. A solution to the transport equation provides the electron intensity as a function of altitude, pitch angle (with respect to the geomagnetic field) and energy. A multi-stream (discrete ordinate) approximation to the transport equation is developed. An analytic solution is obtained in this approximation. The computational scheme obtained by combining the present transport code with the energy degradation method of Swartz (1979) conserves energy identically. The theory provides a framework within which angular distributions can be easily calculated and interpreted. Thus, a detailed study of the angular distributions of 'non-absorbed' electrons (i.e., electrons that have lost just a small fraction of their incident energy) reveals a systematic variation with incident angle and energy, and with penetration depth. The present approach also gives simple yet accurate solutions in low order multi-stream approximations. The accuracy of the four-stream approximation is generally within a few per cent, whereas two-stream results for backscattered mean intensities and fluxes are accurate to within 10-15%. (author)

  5. Optimum MRS site location to minimize spent fuel transportation impacts

    International Nuclear Information System (INIS)

    Hoskins, R.E.

    1987-01-01

    A range of spent fuel transportation system parameters are examined in terms of attributes important to minimizing transportation impacts as a basis for identifying geographic regions best suited for siting a monitored retrievable storage (MRS) facility. Transportation system parameters within existing transport cask design and transportation mode capabilities were systematically analyzed. The optimum MRS location was found to be very sensitive to transportation system assumptions particularly with regard to the relative efficiencies of the reactor-to-MRS and MRS-to-repository components of the system. Moreover, dramatic improvements in the reactor-to-MRS component can be made through use of multiple cask shipment of the largest practical casks by dedicated train compared to the traditional single cask rail (70%) and truck (30%) shipments assumed the Department of Energy in their studies that defined the optimum MRS location in the vicinity of Tennessee. It is important to develop and utilize an efficient transportation system irrespective of whether or not an MRS is in the system. Assuming reasonably achievable efficiency in reactor-to-MRS spent fuel transportation and assigning equal probabilities to the three western sites selected for characterization of being the repository site, the optimum MRS location would be in the far-mid-western states. Based on various geographic criteria including barge access and location in a nuclear service area, the State of Tennessee ranks any place from 12th to the 25th at a penalty of about 30% over the minimum achievable impacts. While minimizing transportation impacts is an important factor, other criteria should also be considered in selecting an MRS site

  6. ASIMETRI INFORMASI DAN UNDERPRICING

    Directory of Open Access Journals (Sweden)

    Tety Anggita Safitri

    2013-03-01

    Full Text Available Tujuan penelitian ini adalah untuk menguji pengaruh asimetri informasi terhadap underpricing. Penelitian ini menggunakan sampel 63 perusahaan yang melakukan penawaran umum perdana di Bursa Efek Indonesia dalam kurun waktu 2005-2010. Analisis data menggunakan regresi linier berganda, yaitu menguji proksi asimetri informasi yang terdiri atas ukuran perusahaan, umur perusahaan, proporsi saham yang ditawarkan kepada masyarakat, reputasi underwriter dan reputasi auditor terhadap underpricing. Hasil penelitian ini mengindikasikan bahwa reputasi underwriter dan reputasi auditor berpengaruh terhadap underpricing. Ukuran perusahaan, umur perusahaan dan proporsi saham yang ditawarkan tidak berpengaruh terhadap underpricing.The aim of this research is to examine the effect of assymetric information on underpricing. This research used a sample of 63 companies that make initial public offering on the Indonesia Stock Exchange in the period of 2005-2010. The data analysis is using multiple linear regression, which is testing the proxy of asymmetric information which consists of the firm size, the firm age, the proportion of shares offered to the public, underwriter reputation and auditor reputation on underpricing. This research indicates that underwriter reputation and auditor reputation have a significant effect on underpricing. The firm size, the firm age and the proportion of shares offered to the public have no significant effect on underpricing.

  7. Traffic improvement and transportation pollution control in Xiamen

    Energy Technology Data Exchange (ETDEWEB)

    Dongxing Yuan; Zilin, Wu

    1996-12-31

    in this paper, the urban traffic improvement and transportation control in Xiamen are highlighted. Xiamen is a port city and an economical special zone of China. As the economy grows, the transportation is developing dramatically and becoming the key for further economic development. The air quality is threatened by the rapid growth of the vehicles in the city. The most urgent task in improving urban traffic is to establish a sound traffic system. The municipal government takes great effort to improve the traffic condition, as well as to reduce green house gases and protect air environment. Some management and technical measures are carried out. Those management measures are mainly as follows: (1) systematic planning of the city arrangement and city functional division, and integrated planning of the urban roads system, (2) putting great emphasis on tail gas monitoring and management, and (3) establishing optimized utilization of motor vehicles. Those included in the main technical measures are (1) making the roads clear, (2) enlarging traffic capacity, and (3) developing the public transport. The most urgent task in improving urban traffic is to establish a sound traffic system. The city municipal government and Transportation Management Bureau plan to make a series of reforms to improve the urban traffic condition, such as building high quality road around the city, reducing the number of one way roads and replacing gasoline buses with electric buses. An optimized traffic system of Xiamen, taking public transport as the main means, is the key to meet the needs of both traffic improvement and urban transportation pollution control.

  8. The Choice between Rights-Preserving Issue Methods: Regulatory and Financial Aspects of Issuing Seasoned Equity in the UK

    OpenAIRE

    Korteweg, A.G.; Renneboog, L.D.R.

    2002-01-01

    This paper examines the choice between two rights-preserving issue methods of seasoned equity offers in the UK as well as the factors determining the offer price and stock market announcement reactions.Firstly, equity issues in the UK are underwritten for different reasons than in other countries.Only severely financially distressed companies choose not to underwrite their share offer. Second, the average announcement reaction to non-underwritten issues is much more negative than to underwrit...

  9. Transportation Accessibility and Location Choice of Japanese-Funded Electronic Information Manufacturing Firms in Shanghai

    Directory of Open Access Journals (Sweden)

    Haining Jiang

    2018-02-01

    Full Text Available With the rapid development of globalization, information communication and transportation, it is argued that the effect of transportation accessibility in the location choice of manufacturing firms has diminished. However, comprehensive and systematic research on the impact of transportation accessibility on firm location choice in cities remains scarce. Taking Shanghai as the research area, this paper uses a catalog of Japanese-funded electronic information manufacturing firms to explore the influence of transportation accessibility on their location choice. The paper first describes firm distribution using the nuclear density estimation method. The Poisson regression model is then used to estimate the significance of transportation accessibility in influencing firm location. The empirical results show that most of the firms are concentrated in the inner suburbs of Shanghai, with only a small number in the outer suburban areas. The spatial coupling relationship between firm distribution and transportation accessibility is significant. These firms tend to choose areas with good accessibility to transportation infrastructure, and, in particular, the effect of airport accessibility is significant. Compared with the joint venture enterprises, wholly-owned Japanese enterprises are more inclined to be in areas with better transportation accessibility.

  10. Transport parameter estimation from lymph measurements and the Patlak equation.

    Science.gov (United States)

    Watson, P D; Wolf, M B

    1992-01-01

    Two methods of estimating protein transport parameters for plasma-to-lymph transport data are presented. Both use IBM-compatible computers to obtain least-squares parameters for the solvent drag reflection coefficient and the permeability-surface area product using the Patlak equation. A matrix search approach is described, and the speed and convenience of this are compared with a commercially available gradient method. The results from both of these methods were different from those of a method reported by Reed, Townsley, and Taylor [Am. J. Physiol. 257 (Heart Circ. Physiol. 26): H1037-H1041, 1989]. It is shown that the Reed et al. method contains a systematic error. It is also shown that diffusion always plays an important role for transmembrane transport at the exit end of a membrane channel under all conditions of lymph flow rate and that the statement that diffusion becomes zero at high lymph flow rate depends on a mathematical definition of diffusion.

  11. Transport of solar electrons in the turbulent interplanetary magnetic field

    Energy Technology Data Exchange (ETDEWEB)

    Ablaßmayer, J.; Tautz, R. C., E-mail: robert.c.tautz@gmail.com [Zentrum für Astronomie und Astrophysik, Technische Universität Berlin, Hardenbergstraße 36, D-10623 Berlin (Germany); Dresing, N., E-mail: dresing@physik.uni-kiel.de [Institut für Experimentelle und Angewandte Physik, Christian-Albrechts-Universität zu Kiel, Leibnizstraße 11, D-24118 Kiel (Germany)

    2016-01-15

    The turbulent transport of solar energetic electrons in the interplanetary magnetic field is investigated by means of a test-particle Monte-Carlo simulation. The magnetic fields are modeled as a combination of the Parker field and a turbulent component. In combination with the direct calculation of diffusion coefficients via the mean-square displacements, this approach allows one to analyze the effect of the initial ballistic transport phase. In that sense, the model complements the main other approach in which a transport equation is solved. The major advancement is that, by recording the flux of particles arriving at virtual detectors, intensity and anisotropy-time profiles can be obtained. Observational indications for a longitudinal asymmetry can thus be explained by tracing the diffusive spread of the particle distribution. The approach may be of future help for the systematic interpretation of observations for instance by the solar terrestrial relations observatory (STEREO) and advanced composition explorer (ACE) spacecrafts.

  12. Chemical Evidence for Vertical Transport from Magma Chambers to the Surface During Mid-Ocean Ridge Volcanic Eruptions

    Science.gov (United States)

    Sinton, J. M.; Rubin, K. H.

    2009-12-01

    Many mid-ocean ridge eruptions show significant internal chemical heterogeneity; in general, the amount of chemical heterogeneity within eruptions scales with erupted volume. These variations reflect magmatic processes occurring in magma reservoirs prior to or possibly during eruption. For example, systematic variations in Mg# with along-axis distance in the early 90’s Aldo-Kihi (S. EPR near 17.5°S), 1996 N. Gorda, 1993 Co-Axial (Juan de Fuca Ridge), and 1991-2 and 2005-6 9°50’N EPR eruptions is unlikely to be related to fractionation during emplacement, and rather reflects variations in sub-axial magma reservoirs prior to eruption. Such variations are inconsistent with well-mixed sub-axial reservoirs and, in some cases, require relatively long-lived, systematic variations in reservoir temperatures along axis. Chemical heterogeneity within the Aldo-Kihi eruption preserves spatial variations in mantle-derived isotopic and trace element ratios with implications for the temporal and spatial scales of magma injections to the crust and along-axis mixing within shallow reservoirs. These spatial variations are difficult to reconcile with significant (> ~1 km) along-axis magma transport, as are striking correlations of chemical compositions with surface geological discontinuities or seismically imaged sub-axial magma chamber reflectors in the S. Hump (S. EPR), 9°50’N EPR, N. Gorda and 1975-1984 Krafla (N. Iceland) eruptive units. Rather, spatial correlations between surface lava compositions and sub-axial magma chamber properties or long-lived axial morphology suggest that most of the erupted magma was transported nearly vertically from the underlying reservoirs to the surface during these eruptions. In the case of the Krafla eruption, coincident deformation suggests a component of lateral melt migration at depth, despite chemical evidence for vertical transport of erupted lava from more than one chemical reservoir. In addition, along-ridge movement of earthquake

  13. Human engineering analysis for the high speed civil transport flight deck

    Science.gov (United States)

    Regal, David M.; Alter, Keith W.

    1993-01-01

    The Boeing Company is investigating the feasibility of building a second generation supersonic transport. If current studies support its viability, this airplane, known as the High Speed Civil Transport (HSCT), could be launched early in the next century. The HSCT will cruise at Mach 2.4, be over 300 feet long, have an initial range of between 5000 and 6000 NM, and carry approximately 300 passengers. We are presently involved in developing an advanced flight deck for the HSCT. As part of this effort we are undertaking a human engineering analysis that involves a top-down, mission driven approach that will allow a systematic determination of flight deck functional and information requirements. The present paper describes this work.

  14. Quality of systematic reviews in pediatric oncology - A systematic review

    NARCIS (Netherlands)

    Lundh, Andreas; Knijnenburg, Sebastiaan L.; Jørgensen, Anders W.; van Dalen, Elvira C.; Kremer, Leontien C. M.

    2009-01-01

    Background: To ensure evidence-based decision making in pediatric oncology systematic reviews are necessary. The objective of our study was to evaluate the methodological quality of all currently existing systematic reviews in pediatric oncology. Methods: We identified eligible systematic reviews

  15. Spin transport in oxygen adsorbed graphene nanoribbon

    Science.gov (United States)

    Kumar, Vipin

    2018-04-01

    The spin transport properties of pristine graphene nanoribbons (GNRs) have been most widely studied using theoretical and experimental tools. The possibilities of oxidation of fabricated graphene based nano electronic devices may change the device characteristics, which motivates to further explore the properties of graphene oxide nanoribbons (GONRs). Therefore, we present a systematic computational study on the spin polarized transport in surface oxidized GNR in antiferromagnetic (AFM) spin configuration using density functional theory combined with non-equilibrium Green's function (NEGF) method. It is found that the conductance in oxidized GNRs is significantly suppressed in the valance band and the conduction band. A further reduction in the conductance profile is seen in presence of two oxygen atoms on the ribbon plane. This change in the conductance may be attributed to change in the surface topology of the ribbon basal plane due to presence of the oxygen adatoms, where the charge transfer take place between the ribbon basal plane and the oxygen atoms.

  16. Heterojunction PbS nanocrystal solar cells with oxide charge-transport layers.

    Science.gov (United States)

    Hyun, Byung-Ryool; Choi, Joshua J; Seyler, Kyle L; Hanrath, Tobias; Wise, Frank W

    2013-12-23

    Oxides are commonly employed as electron-transport layers in optoelectronic devices based on semiconductor nanocrystals, but are relatively rare as hole-transport layers. We report studies of NiO hole-transport layers in PbS nanocrystal photovoltaic structures. Transient fluorescence experiments are used to verify the relevant energy levels for hole transfer. On the basis of these results, planar heterojunction devices with ZnO as the photoanode and NiO as the photocathode were fabricated and characterized. Solution-processed devices were used to systematically study the dependence on nanocrystal size and achieve conversion efficiency as high as 2.5%. Optical modeling indicates that optimum performance should be obtained with thinner oxide layers than can be produced reliably by solution casting. Room-temperature sputtering allows deposition of oxide layers as thin as 10 nm, which enables optimization of device performance with respect to the thickness of the charge-transport layers. The best devices achieve an open-circuit voltage of 0.72 V and efficiency of 5.3% while eliminating most organic material from the structure and being compatible with tandem structures.

  17. Local transport analysis of L-mode plasmas in JT-60 tokamak

    International Nuclear Information System (INIS)

    Hirayama, Toshio; Kikuchi, Mitsuru; Shirai, Hiroshi; Shimizu, Katsuhiro; Yagi, Masatoshi; Koide, Yoshihiko; Ishida, Shinichi; Azumi, Masafumi.

    1991-03-01

    Local heat transport has been studied in auxiliary heated JT-60 plasmas with emphasis on understanding the deteriorated confinement observed in L-mode plasmas. The systematic experiment and analysis have been carried out in L-mode phase of divertor (single null, lower X-point), and limiter discharges with hydrogen neutral beam heating into hydrogen plasmas, based on sets of consistent experimental data including ion temperature profiles from CXR measurements. The deterioration in the energy confinement time with increasing the auxiliary heating power, so-called the power scaling, is mainly due to the degradation in ion energy transport. The confinement improvement as the plasma current increases is followed by both improvement in ion and electron transport properties. It is found that the ion thermal diffusivity has an approval dependence on the density. High ion temperature (T i (0) ≤ 12 keV) L-mode plasmas are attained at high β p up to 3.5. The centrally peaked ion temperature is significantly due to the improvement in ion transport property, which is reduced to the level of the electron thermal diffusivities. (author)

  18. Investigation of Beam Emittance and Beam Transport Line Optics on Polarization

    Energy Technology Data Exchange (ETDEWEB)

    Fiedler, Andrew [Northern Illinois U.; Syphers, Michael [Fermilab

    2017-10-06

    Effects of beam emittance, energy spread, optical parameters and magnet misalignment on beam polarization through particle transport systems are investigated. Particular emphasis will be placed on the beam lines being used at Fermilab for the development of the muon beam for the Muon g-2 experiment, including comparisons with the natural polarization resulting from pion decay, and comments on the development of systematic correlations among phase space variables.

  19. Anisotropic bias dependent transport property of defective phosphorene layer

    Science.gov (United States)

    Umar Farooq, M.; Hashmi, Arqum; Hong, Jisang

    2015-01-01

    Phosphorene is receiving great research interests because of its peculiar physical properties. Nonetheless, no systematic studies on the transport properties modified due to defects have been performed. Here, we present the electronic band structure, defect formation energy and bias dependent transport property of various defective systems. We found that the defect formation energy is much less than that in graphene. The defect configuration strongly affects the electronic structure. The band gap vanishes in single vacancy layers, but the band gap reappears in divacancy layers. Interestingly, a single vacancy defect behaves like a p-type impurity for transport property. Unlike the common belief, we observe that the vacancy defect can contribute to greatly increasing the current. Along the zigzag direction, the current in the most stable single vacancy structure was significantly increased as compared with that found in the pristine layer. In addition, the current along the armchair direction was always greater than along the zigzag direction and we observed a strong anisotropic current ratio of armchair to zigzag direction. PMID:26198318

  20. Carbon Footprint Linked to transport infrastructures

    International Nuclear Information System (INIS)

    Crespo Garcia, L.; Jimenez Arroyo, F.

    2013-01-01

    Quantification of emissions of greenhouse effect gases associated to transport infrastructures has been addressed in different ways. The first tools for this purpose appeared with the application of ISO 14040 standards (Life cycle analysis) that, applied to the particular case of energetic resources, led to a new concept known as carbon footprint. There is a specific standard for this quantification (ISO 14064) according to which, for the case of infrastructures, emissions and environmental effects linked to the whole life cycle are assessed taking into account all the stages: building, exploitation, maintenance and dismantling. the key point to perform this analysis is the accurate definition of a calculation methodology to be applied to the inventory of activities covered, in order to avoid information lacks, overlaps or redundancies. Quantification tools for emissions are effectively a reality, but social and political will, supported by strong economical reasons recognizing energy as a vital resource, is necessary for these tools to be developed, enhanced and used in a systematic way as a key decision element to choice among different transport alternatives. (Author) 23 refs.

  1. Bantam: A Systematic Approach to Reusable Launch Vehicle Technology Development

    Science.gov (United States)

    Griner, Carolyn; Lyles, Garry

    1999-01-01

    The Bantam technology project is focused on providing a low cost launch capability for very small (100 kilogram) NASA and University science payloads. The cost goal has been set at one million dollars per launch. The Bantam project, however, represents much more than a small payload launch capability. Bantam represents a unique, systematic approach to reusable launch vehicle technology development. This technology maturation approach will enable future highly reusable launch concepts in any payload class. These launch vehicle concepts of the future could deliver payloads for hundreds of dollars per pound, enabling dramatic growth in civil and commercial space enterprise. The National Aeronautics and Space Administration (NASA) has demonstrated a better, faster, and cheaper approach to science discovery in recent years. This approach is exemplified by the successful Mars Exploration Program lead by the Jet Propulsion Laboratory (JPL) for the NASA Space Science Enterprise. The Bantam project represents an approach to space transportation technology maturation that is very similar to the Mars Exploration Program. The NASA Advanced Space Transportation Program (ASTP) and Future X Pathfinder Program will combine to systematically mature reusable space transportation technology from low technology readiness to system level flight demonstration. New reusable space transportation capability will be demonstrated at a small (Bantam) scale approximately every two years. Each flight demonstration will build on the knowledge derived from the previous flight tests. The Bantam scale flight demonstrations will begin with the flights of the X-34. The X-34 will demonstrate reusable launch vehicle technologies including; flight regimes up to Mach 8 and 250,000 feet, autonomous flight operations, all weather operations, twenty-five flights in one year with a surge capability of two flights in less than twenty-four hours and safe abort. The Bantam project will build on this initial

  2. Investigating the effects of ABC transporter-based acquired drug resistance mechanisms at the cellular and tissue scale.

    Science.gov (United States)

    Liu, Cong; Krishnan, J; Xu, Xiao Yun

    2013-03-01

    In this paper we systematically investigate the effects of acquired drug resistance at the cellular and tissue scale, with a specific focus on ATP-binding cassette (ABC) transporter-based mechanisms and contrast this with other representative intracellular resistance mechanisms. This is done by developing in silico models wherein the drug resistance mechanism is overlaid on a coarse-grained description of apoptosis; these cellular models are coupled with interstitial drug transport, allowing for a transparent examination of the effect of acquired drug resistances at the tissue level. While ABC transporter-mediated resistance mechanisms counteract drug effect at the cellular level, its tissue-level effect is more complicated, revealing unexpected trends in tissue response as drug stimuli are systematically varied. Qualitatively different behaviour is observed in other drug resistance mechanisms. Overall the paper (i) provides insight into the tissue level functioning of a particular resistance mechanism, (ii) shows that this is very different from other resistance mechanisms of an apparently similar type, and (iii) demonstrates a concrete instance of how the functioning of a negative feedback based cellular adaptive mechanism can have unexpected higher scale effects.

  3. Particle and heavy ion transport code system; PHITS

    International Nuclear Information System (INIS)

    Niita, Koji

    2004-01-01

    Intermediate and high energy nuclear data are strongly required in design study of many facilities such as accelerator-driven systems, intense pulse spallation neutron sources, and also in medical and space technology. There is, however, few evaluated nuclear data of intermediate and high energy nuclear reactions. Therefore, we have to use some models or systematics for the cross sections, which are essential ingredients of high energy particle and heavy ion transport code to estimate neutron yield, heat deposition and many other quantities of the transport phenomena in materials. We have developed general purpose particle and heavy ion transport Monte Carlo code system, PHITS (Particle and Heavy Ion Transport code System), based on the NMTC/JAM code by the collaboration of Tohoku University, JAERI and RIST. The PHITS has three important ingredients which enable us to calculate (1) high energy nuclear reactions up to 200 GeV, (2) heavy ion collision and its transport in material, (3) low energy neutron transport based on the evaluated nuclear data. In the PHITS, the cross sections of high energy nuclear reactions are obtained by JAM model. JAM (Jet AA Microscopic Transport Model) is a hadronic cascade model, which explicitly treats all established hadronic states including resonances and all hadron-hadron cross sections parametrized based on the resonance model and string model by fitting the available experimental data. The PHITS can describe the transport of heavy ions and their collisions by making use of JQMD and SPAR code. The JQMD (JAERI Quantum Molecular Dynamics) is a simulation code for nucleus nucleus collisions based on the molecular dynamics. The SPAR code is widely used to calculate the stopping powers and ranges for charged particles and heavy ions. The PHITS has included some part of MCNP4C code, by which the transport of low energy neutron, photon and electron based on the evaluated nuclear data can be described. Furthermore, the high energy nuclear

  4. Mixing induced reactive transport in fractured crystalline rocks

    International Nuclear Information System (INIS)

    Martinez-Landa, Lurdes; Carrera, Jesus; Dentz, Marco; Fernàndez-Garcia, Daniel; Nardí, Albert; Saaltink, Maarten W.

    2012-01-01

    In this paper the solute retention properties of crystalline fractured rocks due to mixing-induced geochemical reactions are studied. While fractured media exhibit paths of fast flow and transport and thus short residence times for conservative solutes, at the same time they promote mixing and dilution due to strong heterogeneity, which leads to sharp concentration contrasts. Enhanced mixing and dilution have a double effect that favors crystalline fractured media as a possible host medium for nuclear waste disposal. Firstly, peak radionuclide concentrations are attenuated and, secondly, mixing-induced precipitation reactions are enhanced significantly, which leads to radionuclide immobilization. An integrated framework is presented for the effective modeling of these flow, transport and reaction phenomena, and the interaction between them. In a simple case study, the enhanced dilution and precipitation potential of fractured crystalline rocks are systematically studied and quantified and contrasted it to retention and attenuation in an equivalent homogeneous formation.

  5. Three dimensions transport calculations for PWR core; Calcul de coeur R.E.P. en transport 3D

    Energy Technology Data Exchange (ETDEWEB)

    Richebois, E

    2000-07-01

    The objective of this work is to define improved 3-D core calculation methods based on the transport theory. These methods can be particularly useful and lead to more precise computations in areas of the core where anisotropy and steep flux gradients occur, especially near interface and boundary conditions and in regions of high heterogeneity (bundle with absorbent rods). In order to apply the transport theory a new method for calculating reflector constants has been developed, since traditional methods were only suited for 2-group diffusion core calculations and could not be extrapolated to transport calculations. In this thesis work, the new method for obtaining reflector constants is derived regardless of the number of energy groups and of the operator used. The core calculations results using the reflector constants thereof obtained have been validated on the EDF's power reactor Saint Laurent B1 with MOX loading. The advantages of a 3-D core transport calculation scheme have been highlighted as opposed to diffusion methods; there are a considerable number of significant effects and potential advantages to be gained in rod worth calculations for instance. These preliminary results obtained with on particular cycle will have to be confirmed by more systematic analysis. Accidents like MSLB (main steam line break) and LOCA (loss of coolant accident) should also be investigated and constitute challenging situations where anisotropy is high and/or flux gradients are steep. This method is now being validated for others EDF's PWRs' reactors, as well as for experimental reactors and other types of commercial reactors. (author)

  6. Three dimensions transport calculations for PWR core; Calcul de coeur R.E.P. en transport 3D

    Energy Technology Data Exchange (ETDEWEB)

    Richebois, E

    2000-07-01

    The objective of this work is to define improved 3-D core calculation methods based on the transport theory. These methods can be particularly useful and lead to more precise computations in areas of the core where anisotropy and steep flux gradients occur, especially near interface and boundary conditions and in regions of high heterogeneity (bundle with absorbent rods). In order to apply the transport theory a new method for calculating reflector constants has been developed, since traditional methods were only suited for 2-group diffusion core calculations and could not be extrapolated to transport calculations. In this thesis work, the new method for obtaining reflector constants is derived regardless of the number of energy groups and of the operator used. The core calculations results using the reflector constants thereof obtained have been validated on the EDF's power reactor Saint Laurent B1 with MOX loading. The advantages of a 3-D core transport calculation scheme have been highlighted as opposed to diffusion methods; there are a considerable number of significant effects and potential advantages to be gained in rod worth calculations for instance. These preliminary results obtained with on particular cycle will have to be confirmed by more systematic analysis. Accidents like MSLB (main steam line break) and LOCA (loss of coolant accident) should also be investigated and constitute challenging situations where anisotropy is high and/or flux gradients are steep. This method is now being validated for others EDF's PWRs' reactors, as well as for experimental reactors and other types of commercial reactors. (author)

  7. Efficacy of behavioural interventions for transport behaviour change: systematic review, meta-analysis and intervention coding.

    Science.gov (United States)

    Arnott, Bronia; Rehackova, Lucia; Errington, Linda; Sniehotta, Falko F; Roberts, Jennifer; Araujo-Soares, Vera

    2014-11-28

    Reducing reliance on motorised transport and increasing use of more physically active modes of travel may offer an opportunity to address physical inactivity. This review evaluates the evidence for the effects of behavioural interventions to reduce car use for journeys made by adults and codes intervention development and content. The review follows the procedure stated in the registration protocol published in the PROSPERO database (registration number CRD42011001797). Controlled studies evaluating behavioural interventions to reduce car use compared with no interventions or alternative interventions on outcome measures of transport behaviours taken in adult participants are included in this review. Searches were conducted on all records in Applied Social Sciences Index and Abstracts (ASSIA), Ovid Embase, Ovid Medline, Ovid PsycInfo, Scopus, Sociological Abstracts, Transportation Research Information Service (TRIS), Transportation Research International Documentation (TRID), and Web of Science databases. Peer reviewed publications in English language meeting the inclusion criteria are eligible. Methodological quality is assessed using the Cochrane Risk of Bias Tool. Interventions are categorised in terms of behavioural frameworks, theories and techniques. 15 full text articles are included, representing 13 unique studies, with 4895 participants and 27 intervention arms. Risk of bias across the review is appraised as considerable due to the unclear methodological quality of individual studies. Heterogeneity of included studies is considerable. Meta-analyses reveal no significant effect on reduction of frequency of car use or on increasing the proportion of journeys by alternative, more active modes of transport. There is insufficient data relating to alternative outcomes such as distance and duration which may have important health implications. Interventions were top-down but could not be described as theory-based. Intervention efficacy was associated with the use

  8. Reactive transport of aqueous protons in porous media

    KAUST Repository

    McNeece, Colin J.

    2016-10-09

    The sorption of protons determines the surface charge of natural media and is therefore a first-order control on contaminant transport. Significant effort has been extended to develop chemical models that quantify the sorption of protons at the mineral surface. To compare these models’ effect on predicted proton transport, we present analytic solutions for column experiments through silica sand. Reaction front morphology is controlled by the functional relationship between the total sorbed and total aqueous proton concentrations. An inflection point in this function near neutral pH leads to a reversal in the classic front formation mechanism under basic conditions, such that proton desorption leads to a self-sharpening front, while adsorption leads to a spreading front. A composite reaction front comprising both a spreading and self-sharpening segment can occur when the injected and initial concentrations straddle the inflection point. This behavior is unique in single component reactive transport and arises due to the auto-ionization of water rather than electrostatic interactions at the mineral surface. We derive a regime diagram illustrating conditions under which different fronts occur, highlighting areas where model predictions diverge. Chemical models are then compared and validated against a systematic set of column experiments.

  9. High energy particle transport code NMTC/JAM

    International Nuclear Information System (INIS)

    Niita, Koji; Meigo, Shin-ichiro; Takada, Hiroshi; Ikeda, Yujiro

    2001-03-01

    We have developed a high energy particle transport code NMTC/JAM, which is an upgraded version of NMTC/JAERI97. The applicable energy range of NMTC/JAM is extended in principle up to 200 GeV for nucleons and mesons by introducing the high energy nuclear reaction code JAM for the intra-nuclear cascade part. For the evaporation and fission process, we have also implemented a new model, GEM, by which the light nucleus production from the excited residual nucleus can be described. According to the extension of the applicable energy, we have upgraded the nucleon-nucleus non-elastic, elastic and differential elastic cross section data by employing new systematics. In addition, the particle transport in a magnetic field has been implemented for the beam transport calculations. In this upgrade, some new tally functions are added and the format of input of data has been improved very much in a user friendly manner. Due to the implementation of these new calculation functions and utilities, consequently, NMTC/JAM enables us to carry out reliable neutronics study of a large scale target system with complex geometry more accurately and easily than before. This report serves as a user manual of the code. (author)

  10. Blue emitting 1,8-naphthalimides with electron transport properties for organic light emitting diode applications

    Science.gov (United States)

    Ulla, Hidayath; Kiran, M. Raveendra; Garudachari, B.; Ahipa, T. N.; Tarafder, Kartick; Adhikari, Airody Vasudeva; Umesh, G.; Satyanarayan, M. N.

    2017-09-01

    In this article, the synthesis, characterization and use of two novel naphthalimides as electron-transporting emitter materials for organic light emitting diode (OLED) applications are reported. The molecules were obtained by substituting electron donating chloro-phenoxy group at the C-4 position. A detailed optical, thermal, electrochemical and related properties were systematically studied. Furthermore, theoretical calculations (DFT) were performed to get a better understanding of the electronic structures. The synthesized molecules were used as electron transporters and emitters in OLEDs with three different device configurations. The devices with the molecules showed blue emission with efficiencies of 1.89 cdA-1, 0.98 lmW-1, 0.71% at 100 cdm-2. The phosphorescent devices with naphthalimides as electron transport materials displayed better performance in comparison to the device without any electron transporting material and were analogous with the device using standard electron transporting material, Alq3. The results demonstrate that the naphthalimides could play a significant part in the progress of OLEDs.

  11. On the theory of transport in fractured media for the safety analysis of a nuclear waste repository

    International Nuclear Information System (INIS)

    Mukhopadhyay, N.C.

    1982-10-01

    This report aims at developing a systematic theory of the role of fractures in the transport of radionuclides by groundwater, through fractured rocks from a deep-lying nuclear waste repository to the biosphere. Fractures are grouped into four 'irreducible' types: joints, nodes, shear zones and fracture zones, and the physical characteristics which influence radionuclide transport are expressed in mathematical terms. The question of radioactivity retention is then studied for various fracture types, using idealized geometries to model natural forms. Fundamental transport equations are derived for the fracture-pore complex, taking into consideration the special physical characteristics of fractures and the effects of sorption therein. (author)

  12. The transport of zinc and manganese tracers across the Magela Creek system, Northern Territory

    International Nuclear Information System (INIS)

    Airey, P.L.; Calf, G.E.; Davison, A.; Easey, J.F.; Morley, A.

    1983-01-01

    A study has been made of the transport of 54 Mn and 65 Zn released into Magela Creek near Jabiru and into the Leichhardt Billabong on the Magela Plains. Near Jabiru, both isotopes were systematically removed from the surface water by adsorption on the bottom sediments. The 54 Mn was preferentially removed initially; the 65 Zn adsorption became relatively more significant further downstream. Systematic differences are thought to reflect the time-dependent evolution of the species distribution in fresh water systems. The heavy metal tracers injected into the Leichhardt Billabong were non-selectively removed by the vegetation as the radioactive plume crossed onto the shallow flood plain

  13. Research of noise emission sources in railway transport and effective ways of their reduction

    Directory of Open Access Journals (Sweden)

    Zvolenský Peter

    2017-01-01

    Full Text Available In the EU conditions attention is systematically paid to noise reduction on the railways. Because TSI rules systematically tighten limits for noise emissions from railway vehicles, noise research must be addressed by all Member States, as the main technical solutions for railway vehicles and construction technological aspects of railway operations can result in lower noise exposure of affected areas or objects. The paper focuses on theoretical investigation of sources and paths of sound propagation, possibilities of noise reduction both on vehicles and by infrastructure and experimental measurements of the situation in transport practice. Methodology for reducing railway noise around tracks has been presented, too.

  14. A comprehensive, consistent and systematic mathematical model of PEM fuel cells

    International Nuclear Information System (INIS)

    Baschuk, J.J.; Li Xianguo

    2009-01-01

    This paper presents a comprehensive, consistent and systematic mathematical model for PEM fuel cells that can be used as the general formulation for the simulation and analysis of PEM fuel cells. As an illustration, the model is applied to an isothermal, steady state, two-dimensional PEM fuel cell. Water is assumed to be in either the gas phase or as a liquid phase in the pores of the polymer electrolyte. The model includes the transport of gas in the gas flow channels, electrode backing and catalyst layers; the transport of water and hydronium in the polymer electrolyte of the catalyst and polymer electrolyte layers; and the transport of electrical current in the solid phase. Water and ion transport in the polymer electrolyte was modeled using the generalized Stefan-Maxwell equations, based on non-equilibrium thermodynamics. Model simulations show that the bulk, convective gas velocity facilitates hydrogen transport from the gas flow channels to the anode catalyst layers, but inhibits oxygen transport. While some of the water required by the anode is supplied by the water produced in the cathode, the majority of water must be supplied by the anode gas phase, making operation with fully humidified reactants necessary. The length of the gas flow channel has a significant effect on the current production of the PEM fuel cell, with a longer channel length having a lower performance relative to a shorter channel length. This lower performance is caused by a greater variation in water content within the longer channel length

  15. Compliance assurance in the safe transport of radioactive materials in Switzerland

    International Nuclear Information System (INIS)

    Smith, L.

    1994-01-01

    Quality Assurance in the transport of radioactive materials (RAM) has been a legal requirement in Switzerland since 1 January 1990. Some four years later, Switzerland is well on the way to having a comprehensive system of Compliance Assurance covering the transport of RAM. By the end of 1994 Compliance Assurance will be fully operational with regard to nuclear fuel cycle shipments which account for over 90% of all radioactivity transported in Switzerland. Compliance Assurance has been delayed in Switzerland for non-fuel-cycle radioactive material shipments. This has been due to the need to modify the legal infrastructure for the relevant supervisory authorities. Nevertheless, it is hoped to have Compliance Assurance related to Radiation Units (large sources in Type B packages) operational before the end of 1994. Systematic progress is being made regarding Compliance Assurance relating to the movement of smaller sources. This involves a very large number of smaller organisations and will take some time to become routine. (author)

  16. ATP-binding cassette transporters in reproduction: a new frontier

    Science.gov (United States)

    Bloise, E.; Ortiga-Carvalho, T.M.; Reis, F.M.; Lye, S.J.; Gibb, W.; Matthews, S.G.

    2016-01-01

    BACKGROUND The transmembrane ATP-binding cassette (ABC) transporters actively efflux an array of clinically relevant compounds across biological barriers, and modulate biodistribution of many physiological and pharmacological factors. To date, over 48 ABC transporters have been identified and shown to be directly and indirectly involved in peri-implantation events and fetal/placental development. They efflux cholesterol, steroid hormones, vitamins, cytokines, chemokines, prostaglandins, diverse xenobiotics and environmental toxins, playing a critical role in regulating drug disposition, immunological responses and lipid trafficking, as well as preventing fetal accumulation of drugs and environmental toxins. METHODS This review examines ABC transporters as important mediators of placental barrier functions and key reproductive processes. Expression, localization and function of all identified ABC transporters were systematically reviewed using PubMed and Google Scholar websites to identify relevant studies examining ABC transporters in reproductive tissues in physiological and pathophysiological states. Only reports written in English were incorporated with no restriction on year of publication. While a major focus has been placed on the human, extensive evidence from animal studies is utilized to describe current understanding of the regulation and function of ABC transporters relevant to human reproduction. RESULTS ABC transporters are modulators of steroidogenesis, fertilization, implantation, nutrient transport and immunological responses, and function as ‘gatekeepers’ at various barrier sites (i.e. blood-testes barrier and placenta) against potentially harmful xenobiotic factors, including drugs and environmental toxins. These roles appear to be species dependent and change as a function of gestation and development. The best-described ABC transporters in reproductive tissues (primarily in the placenta) are the multidrug transporters p-glycoprotein and

  17. Dopant controlled trap-filling and conductivity enhancement in an electron-transport polymer

    Energy Technology Data Exchange (ETDEWEB)

    Higgins, Andrew, E-mail: aehiggin@princeton.edu, E-mail: kahn@princeton.edu; Kahn, Antoine, E-mail: aehiggin@princeton.edu, E-mail: kahn@princeton.edu [Department of Electrical Engineering, Princeton University, Princeton, New Jersey 08544-5263 (United States); Mohapatra, Swagat K.; Barlow, Stephen; Marder, Seth R. [Center for Organic Photonics and Electronics and School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332-0400 (United States)

    2015-04-20

    Charge transport in organic semiconductors is often inhibited by the presence of tail states that extend into the band gap of a material and act as traps for charge carriers. This work demonstrates the passivation of acceptor tail states by solution processing of ultra-low concentrations of a strongly reducing air-stable organometallic dimer, the pentamethylrhodocene dimer, [RhCp*Cp]{sub 2}, into the electron transport polymer poly([N,N′-bis(2-octyldodecyl)-naphthalene-1,4,5,8-bis(dicarboximide) -2,6-diyl]-alt-5,5′-(2,2′-bithiophene)), P(NDI{sub 2}OD-T{sub 2}). Variable-temperature current-voltage measurements of n-doped P(NDI{sub 2}OD-T{sub 2}) are presented with doping concentration varied through two orders of magnitude. Systematic variation of the doping parameter is shown to lower the activation energy for hopping transport and enhance film conductivity and electron mobility.

  18. Relationship between particle and heat transport in JT-60U plasmas with internal transport barrier

    International Nuclear Information System (INIS)

    Takenaga, Hidenobu; Higashijima, S.; Oyama, N.

    2003-01-01

    The relationship between particle and heat transport in an internal transport barrier (ITB) has been systematically investigated in reversed shear (RS) and high β p ELMy H-mode plasmas in JT-60U. No helium and carbon accumulation inside the ITB is observed even with ion heat transport reduced to a neoclassical level. On the other hand, the heavy impurity argon is accumulated inside the ITB. The argon density profile estimated from the soft x-ray profile is more peaked, by a factor of 2-4 in the RS plasma and of 1.6 in the high β p mode plasma, than the electron density profile. The helium diffusivity (D He ) and the ion thermal diffusivity (χ i ) are at an anomalous level in the high β p mode plasma, where D He and χ i are higher by a factor of 5-10 than the neoclassical value. In the RS plasma, D He is reduced from the anomalous to the neoclassical level, together with χ i . The carbon and argon density profiles calculated using the transport coefficients reduced to the neoclassical level only in the ITB are more peaked than the measured profiles, even when χ i is reduced to the neoclassical level. Argon exhaust from the inside of the ITB is demonstrated by applying ECH in the high β p mode plasma, where both electron and argon density profiles become flatter. The reduction of the neoclassical inward velocity for argon due to the reduction of density gradient is consistent with the experimental observation. In the RS plasma, the density gradient is not decreased by ECH and argon is not exhausted. These results suggest the importance of density control to suppress heavy impurity accumulation. (author)

  19. Relationship between particle and heat transport in JT-60U plasmas with internal transport barrier

    International Nuclear Information System (INIS)

    Takenaga, H.; Higashijima, S.; Oyama, N.

    2003-01-01

    The relationship between particle and heat transport in an internal transport barrier (ITB) has been systematically investigated in reversed shear (RS) and high β p ELMy H-mode plasmas in JT-60U. No helium and carbon accumulation inside the ITB is observed even with ion heat transport reduced to a neoclassical level. On the other hand, the heavy impurity argon is accumulated inside the ITB. The argon density profile estimated from the soft x-ray profile is more peaked, by a factor of 2-4 in the RS plasma and of 1.6 in the high β p mode plasma, than the electron density profile. The helium diffusivity (D He ) and the ion thermal diffusivity (χ i ) are at an anomalous level in the high β p mode plasma, where D He and χ i are higher by a factor of 5-10 than the neoclassical value. In the RS plasma, D He is reduced from the anomalous to the neoclassical level, together with χ i . The carbon and argon density profiles calculated using the transport coefficients reduced to the neoclassical level only in the ITB are more peaked than the measured profiles, even when χ i is reduced to the neoclassical level. Argon exhaust from the inside of the ITB is demonstrated by applying ECH in the high β p mode plasma, where both electron and argon density profiles become flatter. The reduction of the neoclassical inward velocity for argon due to the reduction of density gradient is consistent with the experimental observation. In the RS plasma, the density gradient is not decreased by ECH and argon is not exhausted. These results suggest the importance of density gradient control to suppress heavy impurity accumulation. (author)

  20. Systematic review

    DEFF Research Database (Denmark)

    Enggaard, Helle

    Title: Systematic review a method to promote nursing students skills in Evidence Based Practice Background: Department of nursing educate students to practice Evidence Based Practice (EBP), where clinical decisions is based on the best available evidence, patient preference, clinical experience...... and resources available. In order to incorporate evidence in clinical decisions, nursing students need to learn how to transfer knowledge in order to utilize evidence in clinical decisions. The method of systematic review can be one approach to achieve this in nursing education. Method: As an associate lecturer...... I have taken a Comprehensive Systematic Review Training course provide by Center of Clinical Guidelines in Denmark and Jonna Briggs Institute (JBI) and practice in developing a systematic review on how patients with ischemic heart disease experiences peer support. This insight and experience...

  1. IFPEN Transports Energy Carnot Institute. Annual report 2016. Innovating mobility

    International Nuclear Information System (INIS)

    2017-01-01

    Under the authority of IFP Energies nouvelles, the IFPEN Transports Energie Carnot Institute develops efficient, clean and sustainable technological innovations in the fields of power-train and propulsion systems, energy sectors and industrial thermal processes with CO_2 capture. IFPEN Transports Energie Carnot Institute is a R and D center serving industry, leader in the fields of transport and energy: - Innovative solutions to address technological challenges and market needs (high-efficiency, low-emission power-trains, power-train electrification, energy optimization and onboard control, alternative fuels with low CO_2 emissions, energy generation based on chemical looping combustion); - High-performance experimental resources and digital tools resulting in innovations with reduced costs and development times; - A proactive industrial protection policy; - Support for industrial sectors, covering a very broad range of technological readiness levels; - Transfer of R and D results via joint product development with licensing out operations, strategic partnerships and collaborative research agreements; - An innovation support policy, aimed particularly at micro-companies, SMEs and intermediate-sized companies. IFPEN Transports Energie Carnot Institute has close ties with industry: from micro-companies, SMEs and intermediate-sized companies to major industrial groups; A strong commitment within competitiveness clusters (Mov'eo, LUTB, Systematic, Astech, etc.); A leadership of the automobile sector and the Transport Alliance within the Carnot Institutes; A synergy with networks of academic partners and R and D laboratories with an international influence

  2. Cost-effectiveness of greenhouse gas mitigation in transport: A review of methodological approaches and their impact

    International Nuclear Information System (INIS)

    Kok, Robert; Annema, Jan Anne; Wee, Bert van

    2011-01-01

    A review is given of methodological practices for ex ante cost-effectiveness analysis (CEA) of transport greenhouse gas (GHG) mitigation measures, e.g. fuel economy and CO 2 standards for road vehicles in the US and EU. Besides the fundamental differences between different types of policies and abatement options which inherently result in different CEA outcomes, differences in methodological choices and assumptions are another important source of variation in CEA outcomes. Fourteen methodological issues clustered into six groups are identified on which thirty-three selected studies are systematically reviewed. The potential variation between lower and upper cost-effectiveness estimates for GHG mitigation measures in transport, resulting from different methodological choices and assumptions, lies in the order of $400 per tonne CO 2 -eq. The practise of using CEA for policy-making could improve considerably by clearly indicating the specific purpose of the CEA and its strengths and limitations for policy decisions. Another improvement is related to the dominant approach in transport GHG mitigation studies: the bottom-up financial technical approach which assesses isolated effects, implying considerable limitations for policy-making. A shift to welfare-economic approaches using a hybrid model has the potential to establish an improved assessment of transport GHG mitigation measures based on realistic market responses and behavioural change. - Highlights: ► We identify fourteen important methodological issues clustered into six groups. ► We systematically review thirty-three selected transport GHG mitigation studies. ► Methodological choices can lead to a difference by up to $400 per tonne CO 2 -eq. ► The dominant bottom-up approach has limitations for policy-making. ► Welfare-economic approaches could improve cost-effectiveness analysis.

  3. Metal impurity transport control in JET H-mode plasmas with central ion cyclotron radiofrequency power injection

    DEFF Research Database (Denmark)

    Valisa, M.; Carraro, L.; Predebon, I.

    2011-01-01

    The scan of ion cyclotron resonant heating (ICRH) power has been used to systematically study the pump out effect of central electron heating on impurities such as Ni and Mo in H-mode low collisionality discharges in JET. The transport parameters of Ni and Mo have been measured by introducing...

  4. Aging management assessment of type B transportation packages

    International Nuclear Information System (INIS)

    Sullivan, G.J.; Stahmer, U.; Freeman, E.L.

    2004-01-01

    The condition of a physical system such as a radioactive materials transportation package can change as it ages. The degree to which aging effects are identified, prevented or mitigated will depend on the types of inspections and maintenance performed on the critical components of the system. Routine inspections and maintenance may not address degradation mechanisms that are difficult to observe and can act over long periods of time. Aging management is a systematic effort to ensure that the system performs as designed over its entire service life and that degradation mechanisms do not prematurely end the service life. The Nuclear Waste Management Division (NWMD) of Ontario Power Generation (OPG) has developed an Aging Management Procedure and began performing aging management assessments on its Type B(U) packages. This paper discusses the Procedure and briefly describes the aging management assessment performed on the Roadrunner Transportation Package to demonstrate a practical application of the aging management process

  5. Lithium-ion transport in inorganic solid state electrolyte

    International Nuclear Information System (INIS)

    Gao Jian; Li Hong; Zhao Yu-Sheng; Shi Si-Qi

    2016-01-01

    An overview of ion transport in lithium-ion inorganic solid state electrolytes is presented, aimed at exploring and designing better electrolyte materials. Ionic conductivity is one of the most important indices of the performance of inorganic solid state electrolytes. The general definition of solid state electrolytes is presented in terms of their role in a working cell (to convey ions while isolate electrons), and the history of solid electrolyte development is briefly summarized. Ways of using the available theoretical models and experimental methods to characterize lithium-ion transport in solid state electrolytes are systematically introduced. Then the various factors that affect ionic conductivity are itemized, including mainly structural disorder, composite materials and interface effects between a solid electrolyte and an electrode. Finally, strategies for future material systems, for synthesis and characterization methods, and for theory and calculation are proposed, aiming to help accelerate the design and development of new solid electrolytes. (topical review)

  6. Accelerator and transport line survey and alignment

    International Nuclear Information System (INIS)

    Ruland, R.E.

    1991-10-01

    This paper summarizes the survey and alignment processes of accelerators and transport lines and discusses the propagation of errors associated with these processes. The major geodetic principles governing the survey and alignment measurement space are introduced and their relationship to a lattice coordinate system shown. The paper continues with a broad overview about the activities involved in the step sequence from initial absolute alignment to final smoothing. Emphasis is given to the relative alignment of components, in particular to the importance of incorporating methods to remove residual systematic effects in surveying and alignment operations. Various approaches to smoothing used at major laboratories are discussed. 47 refs., 19 figs., 1 tab

  7. Heterojunction PbS Nanocrystal Solar Cells with Oxide Charge-Transport Layers

    KAUST Repository

    Hyun, Byung-Ryool

    2013-12-23

    Oxides are commonly employed as electron-transport layers in optoelectronic devices based on semiconductor nanocrystals, but are relatively rare as hole-transport layers. We report studies of NiO hole-transport layers in PbS nanocrystal photovoltaic structures. Transient fluorescence experiments are used to verify the relevant energy levels for hole transfer. On the basis of these results, planar heterojunction devices with ZnO as the photoanode and NiO as the photocathode were fabricated and characterized. Solution-processed devices were used to systematically study the dependence on nanocrystal size and achieve conversion efficiency as high as 2.5%. Optical modeling indicates that optimum performance should be obtained with thinner oxide layers than can be produced reliably by solution casting. Roomerature sputtering allows deposition of oxide layers as thin as 10 nm, which enables optimization of device performance with respect to the thickness of the charge-transport layers. The best devices achieve an open-circuit voltage of 0.72 V and efficiency of 5.3% while eliminating most organic material from the structure and being compatible with tandem structures. © 2013 American Chemical Society.

  8. Oriented Morphology and Anisotropic Transport in Uniaxially Stretched Perfluorosulfonate Ionomer Membranes

    Energy Technology Data Exchange (ETDEWEB)

    J Park; J Li; G Divoux; L Madsen; R Moore

    2011-12-31

    Relations between morphology and transport sensitively govern proton conductivity in perfluorsulfonate ionomers (PFSIs) and thus determine useful properties of these technologically important materials. In order to understand such relations, we have conducted a broad systematic study of H{sup +}-form PFSI membranes over a range of uniaxial extensions and water uptakes. On the basis of small-angle X-ray scattering (SAXS) and {sup 2}H NMR spectroscopy, uniaxial deformation induces a strong alignment of ionic domains along the stretching direction. We correlate ionic domain orientation to transport using pulsed-field-gradient {sup 1}H NMR measurements of water diffusion coefficients along the three orthogonal membrane directions. Intriguingly, we observe that uniaxial deformation enhances water transport in one direction (parallel-to-draw direction) while reducing it in the other two directions (two orthogonal directions relative to the stretching direction). We evaluate another important transport parameter, proton conductivity, along two orthogonal in-plane directions. In agreement with water diffusion experiments, orientation of ionic channels increases proton conduction along the stretching direction while decreasing it in the perpendicular direction. These findings provide valuable fodder for optimal application of PFSI membranes as well as for the design of next generation polymer electrolyte membranes.

  9. Automated transport and sorting system in a large reference laboratory: part 1. Evaluation of needs and alternatives and development of a plan.

    Science.gov (United States)

    Hawker, Charles D; Garr, Susan B; Hamilton, Leslie T; Penrose, John R; Ashwood, Edward R; Weiss, Ronald L

    2002-10-01

    Our laboratory, a large, commercial, esoteric reference laboratory, sought some form of total laboratory automation to keep pace with rapid growth of specimen volumes as well as to meet competitive demands for cost reduction and improved turnaround time. We conducted a systematic evaluation of our needs, which led to the development of a plan to implement an automated transport and sorting system. We systematically analyzed and studied our specimen containers, test submission requirements and temperatures, and the workflow and movement of people, specimens, and information throughout the laboratory. We performed an intricate timing study that identified bottlenecks in our manual handling processes. We also evaluated various automation options. The automation alternative viewed to best meet our needs was a transport and sorting system from MDS AutoLab. Our comprehensive plan also included a new standardized transport tube; a centralized automated core laboratory for higher volume tests; a new "automation-friendly" software system for order entry, tracking, and process control; a complete reengineering of our order-entry, handling, and tracking processes; and remodeling of our laboratory facility and specimen processing area. The scope of this project and its potential impact on overall laboratory operations and performance justified the extensive time we invested (nearly 4 years) in a systematic approach to the evaluation, design, and planning of this project.

  10. Electron transport in unipolar InGaN/GaN multiple quantum well structures grown by NH3 molecular beam epitaxy

    KAUST Repository

    Browne, David A.; Mazumder, Baishakhi; Wu, Yuh-Renn; Speck, James S.

    2015-01-01

    on electron transport through quantum well active regions. These unipolar structures served as a test vehicle to test our 2D model of the effect of compositional fluctuations on polarization-induced barriers. Variables that were systematically studied included

  11. Numerical study of the systematic error in Monte Carlo schemes for semiconductors

    Energy Technology Data Exchange (ETDEWEB)

    Muscato, Orazio [Univ. degli Studi di Catania (Italy). Dipt. di Matematica e Informatica; Di Stefano, Vincenza [Univ. degli Studi di Messina (Italy). Dipt. di Matematica; Wagner, Wolfgang [Weierstrass-Institut fuer Angewandte Analysis und Stochastik (WIAS) im Forschungsverbund Berlin e.V. (Germany)

    2008-07-01

    The paper studies the convergence behavior of Monte Carlo schemes for semiconductors. A detailed analysis of the systematic error with respect to numerical parameters is performed. Different sources of systematic error are pointed out and illustrated in a spatially one-dimensional test case. The error with respect to the number of simulation particles occurs during the calculation of the internal electric field. The time step error, which is related to the splitting of transport and electric field calculations, vanishes sufficiently fast. The error due to the approximation of the trajectories of particles depends on the ODE solver used in the algorithm. It is negligible compared to the other sources of time step error, when a second order Runge-Kutta solver is used. The error related to the approximate scattering mechanism is the most significant source of error with respect to the time step. (orig.)

  12. On the theory of transport in fractured media for the safety analysis of a nuclear waste repository

    International Nuclear Information System (INIS)

    Mukhopadhyay, N.C.

    1982-10-01

    This paper aims at developing a systematic theory of the role of fractures in the transport of radionuclides in the fractured rocks by groundwater, from the nuclear waste repository to be built in the deep geological formations, to the biosphere. Fractures are grouped into four 'irreducible' types: joints, nodes, shear zones and fracture zones, and their physical characteristics, having bearings on radionuclide transport, are expressed in mathematical terms. The question of radioactivity retention is then carefully studied for various fracture types, using idealized geometries to mimic natural forms. Fundamental transport equations are derived for the fracture-pore complex, taking into consideration the special physical characteristics of fractures and the effects of sorption therein

  13. Three dimensions transport calculations for PWR core

    International Nuclear Information System (INIS)

    Richebois, E.

    2000-01-01

    The objective of this work is to define improved 3-D core calculation methods based on the transport theory. These methods can be particularly useful and lead to more precise computations in areas of the core where anisotropy and steep flux gradients occur, especially near interface and boundary conditions and in regions of high heterogeneity (bundle with absorbent rods). In order to apply the transport theory a new method for calculating reflector constants has been developed, since traditional methods were only suited for 2-group diffusion core calculations and could not be extrapolated to transport calculations. In this thesis work, the new method for obtaining reflector constants is derived regardless of the number of energy groups and of the operator used. The core calculations results using the reflector constants thereof obtained have been validated on the EDF's power reactor Saint Laurent B1 with MOX loading. The advantages of a 3-D core transport calculation scheme have been highlighted as opposed to diffusion methods; there are a considerable number of significant effects and potential advantages to be gained in rod worth calculations for instance. These preliminary results obtained with on particular cycle will have to be confirmed by more systematic analysis. Accidents like MSLB (main steam line break) and LOCA (loss of coolant accident) should also be investigated and constitute challenging situations where anisotropy is high and/or flux gradients are steep. This method is now being validated for others EDF's PWRs' reactors, as well as for experimental reactors and other types of commercial reactors. (author)

  14. Electronic and optical properties of families of polycyclic aromatic hydrocarbons: A systematic (time-dependent) density functional theory study

    International Nuclear Information System (INIS)

    Malloci, G.; Cappellini, G.; Mulas, G.; Mattoni, A.

    2011-01-01

    Graphical abstract: Electronic absorption spectra of the neutral molecules of the four PAH classes considered, as computed using the real-time real-space TD-DFT. Highlights: →We present a systematic comparative study of families of PAHs. → We computed electronic, optical, and transport properties as a function of size. → We considered oligoacenes, phenacenes, circumacenes, and oligorylenes. → Circumacenes have the best transport properties compared to the other classes. → Oligorylenes are much more efficient in absorbing low-energy photons. - Abstract: Homologous classes of polycyclic aromatic hydrocarbons (PAHs) in their crystalline state are among the most promising materials for organic opto-electronics. Following previous works on oligoacenes we present a systematic comparative study of the electronic, optical, and transport properties of oligoacenes, phenacenes, circumacenes, and oligorylenes. Using density functional theory (DFT) and time-dependent DFT we computed: (i) electron affinities and first ionization energies; (ii) quasiparticle correction to the highest occupied molecular orbital (HOMO)-lowest unoccupied molecular orbital (LUMO) gap; (iii) molecular reorganization energies and (iv) electronic absorption spectra of neutral and ±1 charged systems. The excitonic effects are estimated by comparing the optical gap and the quasiparticle corrected HOMO-LUMO energy gap. For each molecular property computed, general trends as a function of molecular size and charge state are discussed. Overall, we find that circumacenes have the best transport properties, displaying a steeper decrease of the molecular reorganization energy at increasing sizes, while oligorylenes are much more efficient in absorbing low-energy photons in comparison to the other classes.

  15. Time course of ongoing activity during neuritis and following axonal transport disruption.

    Science.gov (United States)

    Satkeviciute, Ieva; Goodwin, George; Bove, Geoffrey M; Dilley, Andrew

    2018-05-01

    Local nerve inflammation (neuritis) leads to ongoing activity and axonal mechanical sensitivity (AMS) along intact nociceptor axons and disrupts axonal transport. This phenomenon forms the most feasible cause of radiating pain, such as sciatica. We have previously shown that axonal transport disruption without inflammation or degeneration also leads to AMS but does not cause ongoing activity at the time point when AMS occurs, despite causing cutaneous hypersensitivity. However, there have been no systematic studies of ongoing activity during neuritis or noninflammatory axonal transport disruption. In this study, we present the time course of ongoing activity from primary sensory neurons following neuritis and vinblastine-induced axonal transport disruption. Whereas 24% of C/slow Aδ-fiber neurons had ongoing activity during neuritis, few (disruption of axonal transport without inflammation does not lead to ongoing activity in sensory neurons, including nociceptors, but does cause a rapid and transient development of AMS. Because it is proposed that AMS underlies mechanically induced radiating pain, and a transient disruption of axonal transport (as previously reported) leads to transient AMS, it follows that processes that disrupt axonal transport, such as neuritis, must persist to maintain AMS and the associated symptoms. NEW & NOTEWORTHY Many patients with radiating pain lack signs of nerve injury on clinical examination but may have neuritis, which disrupts axonal transport. We have shown that axonal transport disruption does not induce ongoing activity in primary sensory neurons but does cause transient axonal mechanical sensitivity. The present data complete a profile of key axonal sensitivities following axonal transport disruption. Collectively, this profile supports that an active peripheral process is necessary for maintained axonal sensitivities.

  16. Systematic review automation technologies

    Science.gov (United States)

    2014-01-01

    Systematic reviews, a cornerstone of evidence-based medicine, are not produced quickly enough to support clinical practice. The cost of production, availability of the requisite expertise and timeliness are often quoted as major contributors for the delay. This detailed survey of the state of the art of information systems designed to support or automate individual tasks in the systematic review, and in particular systematic reviews of randomized controlled clinical trials, reveals trends that see the convergence of several parallel research projects. We surveyed literature describing informatics systems that support or automate the processes of systematic review or each of the tasks of the systematic review. Several projects focus on automating, simplifying and/or streamlining specific tasks of the systematic review. Some tasks are already fully automated while others are still largely manual. In this review, we describe each task and the effect that its automation would have on the entire systematic review process, summarize the existing information system support for each task, and highlight where further research is needed for realizing automation for the task. Integration of the systems that automate systematic review tasks may lead to a revised systematic review workflow. We envisage the optimized workflow will lead to system in which each systematic review is described as a computer program that automatically retrieves relevant trials, appraises them, extracts and synthesizes data, evaluates the risk of bias, performs meta-analysis calculations, and produces a report in real time. PMID:25005128

  17. Statistical properties of turbulent transport and fluctuations in tokamak and stellarator devices

    Energy Technology Data Exchange (ETDEWEB)

    Hidalgo, C; Pedrosa, M A; Milligen, B Van; Sanchez, E; Balbin, R; Garcia-Cortes, I [Euratom-CIEMAT Association, Madrid (Spain); Bleuel, J; Giannone, L.; Niedermeyer, H [Euratom-IPP Association, Garching (Germany)

    1997-05-01

    The statistical properties of fluctuations and turbulent transport have been studied in the plasma boundary region of stellarator (TJ-IU, W7-AS) and tokamak (TJ-I) devices. The local flux probability distribution function shows the bursty character of the flux and presents a systematic change as a function of the radial location. There exist large amplitude transport bursts that account for a significant part of the total flux. There is a strong similarity between the statistical properties of the turbulent fluxes in different devices. The value of the radial coherence associated with fluctuations and turbulent transport is strongly intermittent. This result emphasizes the importance of measurements with time resolution in understanding the interplay between the edge and the core regions in the plasma. For measurements in the plasma edge region of the TJ-IU torsatron, the turbulent flux does not, in general, show a larger radial coherence than the one associated with the fluctuations. (author). 14 refs, 6 figs.

  18. Interplay of Drug-Metabolizing Enzymes and Transporters in Drug Absorption and Disposition.

    Science.gov (United States)

    Shi, Shaojun; Li, Yunqiao

    2014-01-01

    In recent years, the functional interplay between drug-metabolizing enzymes (DMEs) and drug transporters (DTs) in drug absorption and disposition, as well as the complex drug interactions (DIs), has become an intriguing contention, which has also been termed the "transport-metabolism interplay". The current mechanistic understanding for this interplay is first discussed. In the present article, studies investigating the interplay between cytochrome P450 enzymes (CYPs) and efflux transporters have been systematically reviewed in vitro, in situ, in silico, in animals and humans, followed by CYPs-uptake transporters, CYPs-uptake transporters-efflux transporters, and phase II metabolic enzymes-transporters interplay studies. Although several cellular, isolated organ and whole animal studies, in conjunction with simulation and modelling, have addressed the issue that DMEs and DTs can work cooperatively to affect the bioavailability of shared substrate drugs, convincing evidences in human studies are still lacking. Furthermore, the functional interplay between DMEs and DTs will be highly substrate- and dose- dependent. Additionally, we review recent studies to evaluate the influence of genetic variations in the interplay between DMEs and DTs, which might be helpful for the prediction of pharmacokinetics (PK) and possible DIs in human more correctly. There is strong evidence of coordinately regulated DEMs and DTs gene expression and protein activity (e.g. nuclear receptors). Taken together, further investigations and analysis are urgently needed to explore the functional interplay of DMEs and DTs and to delineate the underlying mechanisms.

  19. National Space Transportation System (NSTS) technology needs

    Science.gov (United States)

    Winterhalter, David L.; Ulrich, Kimberly K.

    1990-01-01

    The National Space Transportation System (NSTS) is one of the Nation's most valuable resources, providing manned transportation to and from space in support of payloads and scientific research. The NSTS program is currently faced with the problem of hardware obsolescence, which could result in unacceptable schedule and cost impacts to the flight program. Obsolescence problems occur because certain components are no longer being manufactured or repair turnaround time is excessive. In order to achieve a long-term, reliable transportation system that can support manned access to space through 2010 and beyond, NASA must develop a strategic plan for a phased implementation of enhancements which will satisfy this long-term goal. The NSTS program has initiated the Assured Shuttle Availability (ASA) project with the following objectives: eliminate hardware obsolescence in critical areas, increase reliability and safety of the vehicle, decrease operational costs and turnaround time, and improve operational capability. The strategy for ASA will be to first meet the mandatory needs - keep the Shuttle flying. Non-mandatory changes that will improve operational capability and enhance performance will then be considered if funding is adequate. Upgrade packages should be developed to install within designated inspection periods, grouped in a systematic approach to reduce cost and schedule impacts, and allow the capability to provide a Block 2 Shuttle (Phase 3).

  20. On the theory of transport of fluids in fractured media for the safety analysis of a nuclear waste repository

    International Nuclear Information System (INIS)

    Mukhopadhyay, N.C.

    1983-01-01

    A systematic theory is developed of the role of fractures in the transport of radionuclides by groundwater through fractured rocks from the nuclear waste repository to be built in deep geologic formations to the biosphere. Fractures are grouped into four ''irreducible'' types: joints, nodes, shear zones, and fracture zones, and their geometrical and sorption characteristics, having bearings on radionuclide transport, are expressed in mathematical terms. The question of radioactivity retention in various fracture types is then carefully studied using idealized geometries to mimic natural forms. Fundamental transport equations are derived for the fracture-pore complex, taking into consideration the special physical characteristics of fractures and the effects of sorption therein

  1. Modeling field scale unsaturated flow and transport processes

    International Nuclear Information System (INIS)

    Gelhar, L.W.; Celia, M.A.; McLaughlin, D.

    1994-08-01

    The scales of concern in subsurface transport of contaminants from low-level radioactive waste disposal facilities are in the range of 1 to 1,000 m. Natural geologic materials generally show very substantial spatial variability in hydraulic properties over this range of scales. Such heterogeneity can significantly influence the migration of contaminants. It is also envisioned that complex earth structures will be constructed to isolate the waste and minimize infiltration of water into the facility. The flow of water and gases through such facilities must also be a concern. A stochastic theory describing unsaturated flow and contamination transport in naturally heterogeneous soils has been enhanced by adopting a more realistic characterization of soil variability. The enhanced theory is used to predict field-scale effective properties and variances of tension and moisture content. Applications illustrate the important effects of small-scale heterogeneity on large-scale anisotropy and hysteresis and demonstrate the feasibility of simulating two-dimensional flow systems at time and space scales of interest in radioactive waste disposal investigations. Numerical algorithms for predicting field scale unsaturated flow and contaminant transport have been improved by requiring them to respect fundamental physical principles such as mass conservation. These algorithms are able to provide realistic simulations of systems with very dry initial conditions and high degrees of heterogeneity. Numerical simulation of the movement of water and air in unsaturated soils has demonstrated the importance of air pathways for contaminant transport. The stochastic flow and transport theory has been used to develop a systematic approach to performance assessment and site characterization. Hypothesis-testing techniques have been used to determine whether model predictions are consistent with observed data

  2. [Risk assessment expanded accident insurance for children].

    Science.gov (United States)

    Sittaro, N A

    1998-08-01

    Disability is a well known and tragic event for children. While adults are an established group for specific disability insurance cover, children were often neglected in the past. Although parents, organizations and paediatricans are aware of the risk, children specific incidence rates for disability are hardly available. The only sufficient source for some statistical data are the accident statistics because they represent a substantial group of specific cause related disability for children. Incidence rates for disease related chronic severe impairment or disability in children are either derived by single disease research or actuarial calculation of the German Social Disability Registration. Based on this statistical background, an extended accident insurance for children was introduced in Germany covering both accidents and disabling diseases. The key limitation for all variations of this insurance are exclusion clauses for congential diseases and mental disorders. This insurance requires a new approach in underwriting of the health risks. Because of the substantial number of impaired children, a simple decline of substandard cases are unacceptable. The early experience or medical underwriting shows predominantly health impairments of the following types: allergies, bronchial asthma, ectopic eczema (neurodermitis), disorders of speech and articulation, vision disorders and mental impairments. The suggested solution for underwriting of substandard risks is the predetermination of the possible future maximum degree of disability. The need for underwriting guidelines is supported by the market impact of the new disability cover with thousands of insurance policies issued in the first month after introduction.

  3. Experimental and analytical study of interfacial area transport phenomena in a vertical two-phase flow

    International Nuclear Information System (INIS)

    Huh, Byung-Gil; Euh, Dong-Jin; Yun, Byong-Jo; Youn, Young-Jung; Yoon, Han-Yeong; Song, Chul-Hwa

    2005-03-01

    The number density transport equations for various bubble groups are used to predict the void fraction and the interfacial area concentration. As the closure relations for number density transport equation, the coalescence due to random collisions and the breakup due to the impact of turbulent eddies is modified based on the previous studies and the bubble expansion term due to the pressure reduction is considered. Also, the coalescence due to a wake entrainment is modeled newly to apply to the number density transport equation. In order to predict the local experimental data, the code is developed that the two-fluid model is coupled systematically with the number density transport equation for each bubble group. As for the results of the numerical analysis, the void fraction and interfacial area concentration are predicted well by the developed code and models although some deviations exist in the values between the prediction and experiment, especially, for the high void fraction conditions

  4. Experimental and analytical study of interfacial area transport phenomena in a vertical two-phase flow

    Energy Technology Data Exchange (ETDEWEB)

    Huh, Byung-Gil; Euh, Dong-Jin; Yun, Byong-Jo; Youn, Young-Jung; Yoon, Han-Yeong; Song, Chul-Hwa

    2005-03-01

    The number density transport equations for various bubble groups are used to predict the void fraction and the interfacial area concentration. As the closure relations for number density transport equation, the coalescence due to random collisions and the breakup due to the impact of turbulent eddies is modified based on the previous studies and the bubble expansion term due to the pressure reduction is considered. Also, the coalescence due to a wake entrainment is modeled newly to apply to the number density transport equation. In order to predict the local experimental data, the code is developed that the two-fluid model is coupled systematically with the number density transport equation for each bubble group. As for the results of the numerical analysis, the void fraction and interfacial area concentration are predicted well by the developed code and models although some deviations exist in the values between the prediction and experiment, especially, for the high void fraction conditions.

  5. Systematic Multi‐Scale Model Development Strategy for the Fragrance Spraying Process and Transport

    DEFF Research Database (Denmark)

    Heitzig, M.; Rong, Y.; Gregson, C.

    2012-01-01

    The fast and efficient development and application of reliable models with appropriate degree of detail to predict the behavior of fragrance aerosols are challenging problems of high interest to the related industries. A generic modeling template for the systematic derivation of specific fragrance......‐aided modeling framework, which is structured based on workflows for different general modeling tasks. The benefits of the fragrance spraying template are highlighted by a case study related to the derivation of a fragrance aerosol model that is able to reflect measured dynamic droplet size distribution profiles...... aerosol models is proposed. The main benefits of the fragrance spraying template are the speed‐up of the model development/derivation process, the increase in model quality, and the provision of structured domain knowledge where needed. The fragrance spraying template is integrated in a generic computer...

  6. Land use and transport relationships: A perspective from the United States

    Energy Technology Data Exchange (ETDEWEB)

    Seskin, S.N.

    1995-12-31

    As transportation and land use planners and policy makers world wide grapple with the increasingly challenging consequences of automobile use, there is a growing need to communicate globally about both the knowledge of interactions between transport and land use and the ability to analyze these relationships in a systematic manner. As the world`s largest consumer of energy in general and petroleum in particular, the United States continues to conduct research and innovate in integrated transportation and land use policy issues. The need for improving the state of knowledge and practice, however, is more compelling in developing nations, such as Chile and Thailand, from which, despite their transportation and environmental problems, the United States in fact has much to learn. Nevertheless it is instructive to take a long and broad look at the way the United States is planning and building urban environments. This paper focuses on four aspects of that effort. The first is the state of knowledge on the relationships between land use and travel demand. The second is the analytic tools used to evaluate these relationships. Third is the array of approaches used by government to integrate transport and land use. The last is the ways in which individuals and organizations outside of the formal structure of government participate in metropolitan planning and development.

  7. Improving charge transport property and energy transfer with carbon quantum dots in inverted polymer solar cells

    International Nuclear Information System (INIS)

    Liu, Chunyu; Chang, Kaiwen; Guo, Wenbin; Li, Hao; Shen, Liang; Chen, Weiyou; Yan, Dawei

    2014-01-01

    Carbon quantum dots (Cdots) are synthesized by a simple method and introduced into active layer of polymer solar cells (PSCs). The performance of doped devices was apparently improved, and the highest power conversion efficiency of 7.05% was obtained, corresponding to a 28.2% enhancement compared with that of the contrast device. The charge transport properties, resistance, impedance, and transient absorption spectrum are systematically investigated to explore how the Cdots affect on PSCs performance. This study reveals the importance of Cdots in enhancing the efficiency of PSCs and gives insight into the mechanism of charge transport improvement.

  8. Optimizing Bus Passenger Complaint Service through Big Data Analysis: Systematized Analysis for Improved Public Sector Management

    Directory of Open Access Journals (Sweden)

    Weng-Kun Liu

    2016-12-01

    Full Text Available With the advances in industry and commerce, passengers have become more accepting of environmental sustainability issues; thus, more people now choose to travel by bus. Government administration constitutes an important part of bus transportation services as the government gives the right-of-way to transportation companies allowing them to provide services. When these services are of poor quality, passengers may lodge complaints. The increase in consumer awareness and developments in wireless communication technologies have made it possible for passengers to easily and immediately submit complaints about transportation companies to government institutions, which has brought drastic changes to the supply–demand chain comprised of the public sector, transportation companies, and passengers. This study proposed the use of big data analysis technology including systematized case assignment and data visualization to improve management processes in the public sector and optimize customer complaint services. Taichung City, Taiwan, was selected as the research area. There, the customer complaint management process in public sector was improved, effectively solving such issues as station-skipping, allowing the public sector to fully grasp the service level of transportation companies, improving the sustainability of bus operations, and supporting the sustainable development of the public sector–transportation company–passenger supply chain.

  9. Earth's portfolio of extreme sediment transport events

    Science.gov (United States)

    Korup, Oliver

    2012-05-01

    Quantitative estimates of sediment flux and the global cycling of sediments from hillslopes to rivers, estuaries, deltas, continental shelves, and deep-sea basins have a long research tradition. In this context, extremely large and commensurately rare sediment transport events have so far eluded a systematic analysis. To start filling this knowledge gap I review some of the highest reported sediment yields in mountain rivers impacted by volcanic eruptions, earthquake- and storm-triggered landslide episodes, and catastrophic dam breaks. Extreme specific yields, defined here as those exceeding the 95th percentile of compiled data, are ~ 104 t km- 2 yr- 1 if averaged over 1 yr. These extreme yields vary by eight orders of magnitude, but systematically decay with reference intervals from minutes to millennia such that yields vary by three orders of magnitude for a given reference interval. Sediment delivery from natural dam breaks and pyroclastic eruptions dominate these yields for a given reference interval. Even if averaged over 102-103 yr, the contribution of individual disturbances may remain elevated above corresponding catchment denudation rates. I further estimate rates of sediment (re-)mobilisation by individual giant terrestrial and submarine mass movements. Less than 50 postglacial submarine mass movements have involved an equivalent of ~ 10% of the contemporary annual global flux of fluvial sediment to Earth's oceans, while mobilisation rates by individual events rival the decadal-scale sediment discharge from tectonically active orogens such as Taiwan or New Zealand. Sediment flushing associated with catastrophic natural dam breaks is non-stationary and shows a distinct kink at the last glacial-interglacial transition, owing to the drainage of very large late Pleistocene ice-marginal lakes. Besides emphasising the contribution of high-magnitude and low-frequency events to the global sediment cascade, these findings stress the importance of sediment storage

  10. Lift truck safety review

    Energy Technology Data Exchange (ETDEWEB)

    Cadwallader, L.C.

    1997-03-01

    This report presents safety information about powered industrial trucks. The basic lift truck, the counterbalanced sit down rider truck, is the primary focus of the report. Lift truck engineering is briefly described, then a hazard analysis is performed on the lift truck. Case histories and accident statistics are also given. Rules and regulations about lift trucks, such as the US Occupational Safety an Health Administration laws and the Underwriter`s Laboratories standards, are discussed. Safety issues with lift trucks are reviewed, and lift truck safety and reliability are discussed. Some quantitative reliability values are given.

  11. Spin-dependent tunneling transport in a lateral magnetic diode

    International Nuclear Information System (INIS)

    Wang, Yu; Shi, Ying

    2012-01-01

    Based on the gate-tunable two-dimensional electron gas, we have constructed laterally a double-barrier resonant tunneling structure by employing a peculiar triple-gate configuration, namely a ferromagnetic gate sandwiched closely by a pair of Schottky gates. Because of the in-plane stray field of ferromagnetic gate, the resulting bound spin state in well gives rise to the remarkable resonant spin polarization following the spin-dependent resonant tunneling regime. Importantly, by aligning the bound spin state through surface gate-voltage configuration, this resonant spin polarization can be externally manipulated, showing the desirable features for the spin-logic device applications. -- Highlights: ► A lateral spin-RTD was proposed by applying triple-gate modulated 2DEG. ► Spin-dependent resonant tunneling transport and large resonant spin polarization has been clarified from the systematic simulation. ► Both electric and/or magnetic strategies can be employed to modulate the system spin transport, providing the essential features for the spin-logic application.

  12. The systematization of practice

    DEFF Research Database (Denmark)

    Vidal, Rene Victor Valqui

    2002-01-01

    this paper presents an approach for the systematization of practical experiences whitin Operations Research, Community work, Systems Sciences, Action Research, etc. A case study is presented: the systematization of the activities of a development center in Denmark.......this paper presents an approach for the systematization of practical experiences whitin Operations Research, Community work, Systems Sciences, Action Research, etc. A case study is presented: the systematization of the activities of a development center in Denmark....

  13. Factores que condicionan el rendimiento del transporte

    Directory of Open Access Journals (Sweden)

    Mediavilla, A.

    1963-09-01

    Full Text Available The efficiency of motor transport depends on the rational and precise coordination of the various factors which affect movement by motor vehicles, namely: Correct space and time planning. Speed, by using suitable material and exploiting effectively the power and the capacity of the drivers. Continuity of performance, due to a systematic and efficient maintenance service and intelligent traffic control. Flexibility to introduce modifications in the existing schedules, without interrupting the flow of traffic. By applying effectively the above principles it will be possible to organise transport in the best possible manner. Briefly the above requirements can be summarised thus: «to place, rapidly and regularly, at the preappointed places, all the necessary material for the execution of a particular project».El rendimiento del transporte efectuado por vehículos automóviles, depende de la coordinación racional y armónica de los principios que rigen los movimientos motorizados: Ordenación en tiempo y espacio. Rapidez, mediante el uso del adecuado material y el aprovechamiento de su potencia y de la capacidad de los conductores. Continuidad, merced a un entretenimiento constante y eficaz y a tina inteligente regulación del tráfico. Flexibilidad para introducir, en los movimientos, las modificaciones que se estimen convenientes, sin interrumpir los desplazamientos. Con la aplicación acertada de estos principios se logrará cumplir, en condiciones óptimas, la misión del transporte, la cual puede ser definida como: «situar, con rapidez y regularidad en los lugares prefijados, todos los elementos precisos para el normal desarrollo y ejecución de un plan».

  14. "Assessing the methodological quality of systematic reviews in radiation oncology: A systematic review".

    Science.gov (United States)

    Hasan, Haroon; Muhammed, Taaha; Yu, Jennifer; Taguchi, Kelsi; Samargandi, Osama A; Howard, A Fuchsia; Lo, Andrea C; Olson, Robert; Goddard, Karen

    2017-10-01

    The objective of our study was to evaluate the methodological quality of systematic reviews and meta-analyses in Radiation Oncology. A systematic literature search was conducted for all eligible systematic reviews and meta-analyses in Radiation Oncology from 1966 to 2015. Methodological characteristics were abstracted from all works that satisfied the inclusion criteria and quality was assessed using the critical appraisal tool, AMSTAR. Regression analyses were performed to determine factors associated with a higher score of quality. Following exclusion based on a priori criteria, 410 studies (157 systematic reviews and 253 meta-analyses) satisfied the inclusion criteria. Meta-analyses were found to be of fair to good quality while systematic reviews were found to be of less than fair quality. Factors associated with higher scores of quality in the multivariable analysis were including primary studies consisting of randomized control trials, performing a meta-analysis, and applying a recommended guideline related to establishing a systematic review protocol and/or reporting. Systematic reviews and meta-analyses may introduce a high risk of bias if applied to inform decision-making based on AMSTAR. We recommend that decision-makers in Radiation Oncology scrutinize the methodological quality of systematic reviews and meta-analyses prior to assessing their utility to inform evidence-based medicine and researchers adhere to methodological standards outlined in validated guidelines when embarking on a systematic review. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Atomistic Force Field for Pyridinium-Based Ionic Liquids: Reliable Transport Properties

    DEFF Research Database (Denmark)

    Voroshylova, I. V.; Chaban, V. V.

    2014-01-01

    Reliable force field (FF) is a central issue in successful prediction of physical chemical properties via computer simulations. This work introduces refined FF parameters for six popular ionic liquids (ILs) of the pyridinium family (butylpyridinium tetrafluoroborate, bis(trifluoromethanesulfonyl)......Reliable force field (FF) is a central issue in successful prediction of physical chemical properties via computer simulations. This work introduces refined FF parameters for six popular ionic liquids (ILs) of the pyridinium family (butylpyridinium tetrafluoroborate, bis......(trifluoromethanesulfonyl)imide, dicyanamide, hexafluorophosphate, triflate, chloride). We elaborate a systematic procedure, which allows accounting for specific cationanion interactions in the liquid phase. Once these interactions are described accurately, all experimentally determined transport properties can be reproduced. We prove...... and elevated temperature. The developed atomistic models provide a systematic refinement upon the well-known Canongia LopesPadua (CL&P) FF. Together with the original CL&P parameters the present models foster a computational investigation of ionic liquids....

  16. Influence of coupling phenomena on the transport through compacted clays

    Energy Technology Data Exchange (ETDEWEB)

    Rosanne, M.; Koudina, N.; Adler, P.M. [IPGP, Paris (France); Tevissen, E. [ANDRA, Dept. Etude-Experimentation et Calcul, Chatenay Malabry (France)

    2001-07-01

    Our principal motivation was to study the influence of the coupling phenomena on transport through compacted clays. Coupled transports may occur when a pressure gradient {nabla}P, and electrical field E and a concentration gradient {nabla}C interact. These three gradients induce three fluxes. A flow is generated characterized by the seepage velocity U; a solute flux J{sub L} and a current density I are generated. Close to equilibrium, when the gradients are not to large, the problem is linear and the fluxes are linear functions of the gradients. A first series of experiments was performed with argillite to determine the diagonal properties, i.e., permeability, conductivity, and diffusion coefficient. In a second series of experiments, the voltage resulting from an imposed concentration gradient between two reservoirs separated by a clay sample was systematically measured; this corresponds to the coefficient L{sub 13}. (orig.)

  17. Transport properties through graphene grain boundaries: strain effects versus lattice symmetry

    Science.gov (United States)

    Hung Nguyen, V.; Hoang, Trinh X.; Dollfus, P.; Charlier, J.-C.

    2016-06-01

    As most materials available at the macroscopic scale, graphene samples usually appear in a polycrystalline form and thus contain grain boundaries. In the present work, the effect of uniaxial strain on the electronic transport properties through graphene grain boundaries is investigated using atomistic simulations. A systematic picture of transport properties with respect to the strain and lattice symmetry of graphene domains on both sides of the boundary is provided. In particular, it is shown that strain engineering can be used to open a finite transport gap in all graphene systems where the two domains are arranged in different orientations. This gap value is found to depend on the strain magnitude, on the strain direction and on the lattice symmetry of graphene domains. By choosing appropriately the strain direction, a large transport gap of a few hundred meV can be achieved when applying a small strain of only a few percents. For a specific class of graphene grain boundary systems, strain engineering can also be used to reduce the scattering on defects and thus to significantly enhance the conductance. With a large strain-induced gap, these graphene heterostructures are proposed to be promising candidates for highly sensitive strain sensors, flexible electronic devices and p-n junctions with non-linear I-V characteristics.

  18. Systematics of coal acquisition in Companhia Siderurgica de Tubarao; Sistematica de aquisicao de carvoes na Companhia Siderurgica de Tubarao

    Energy Technology Data Exchange (ETDEWEB)

    Gouvea, Sandra Regina; Gallupi, Paulo Roberto; Vargas, Geraldo A. [Companhia Siderurgica Tubarao, ES (Brazil)

    1993-12-31

    This work presents the systematics adopted by several Brazilian metallurgic companies for the the acquisition and transportation of imported coal. The cooperation among the companies resulted in better prices and quality. Special aspects concerning the negotiation and technical issues are presented. Special emphasis is giving to the system adopted at Companhia Siderurgica de Tubarao 8 figs.

  19. Systematics of coal acquisition in Companhia Siderurgica de Tubarao; Sistematica de aquisicao de carvoes na Companhia Siderurgica de Tubarao

    Energy Technology Data Exchange (ETDEWEB)

    Gouvea, Sandra Regina; Gallupi, Paulo Roberto; Vargas, Geraldo A [Companhia Siderurgica Tubarao, ES (Brazil)

    1994-12-31

    This work presents the systematics adopted by several Brazilian metallurgic companies for the the acquisition and transportation of imported coal. The cooperation among the companies resulted in better prices and quality. Special aspects concerning the negotiation and technical issues are presented. Special emphasis is giving to the system adopted at Companhia Siderurgica de Tubarao 8 figs.

  20. Systematic classification of civil society contributions to nuclear safeguards

    Energy Technology Data Exchange (ETDEWEB)

    Kalinowski, Martin B. [Universitaet Hamburg, Carl Friedrich von Weizsaecker, Centre for Science and Peace Research (ZNF) Hamburg (Germany)

    2012-06-15

    Civil Society is increasingly involved in the policy area of international arms control. Their opportunities are very limited for compliance control in the nuclear nonproliferation regime due to its particular sensitivity. The severe gaps of nuclear safeguards with respect to the capabilities to detect clandestine facilities render marginal civil society contributions highly influential and controversial. More and more data get available for the civil society that can be used to expose potential violations of the NPT. A systematic framework is presented to classify civil society contributions that allows for a systematic study. This classification uses the two parameters (a) affected safeguards stage and (b) degree of integration with the official procedures. These parameters may have the following defined values: (a) The affected safeguards stage can be i. Development and demonstration of new methodologies and technologies ii. Fact finding and data gathering iii. Sharing and publication of data and information iv. Technical analysis of data and information v. Determination of non-compliance vi. Political interpretation (b) The degree of integration can be i. Without a relation ii. Indirect connection iii. Informal interaction iv. Official contribution or mandate. A prominent example for civil society contributions is the increasing availability and capability to acquire and analyze satellite images. An emerging field is environmental sampling, analysis and related atmospheric transport simulation. These and other opportunities are put in the systematic framework to discuss their demonstrated and potential impact. In particular, possible contributions that civil society may offer for improving the detectability of unreported facilities and activities are considered with their chances and risks.

  1. Comparison of search strategies in systematic reviews of adverse effects to other systematic reviews.

    Science.gov (United States)

    Golder, Su; Loke, Yoon K; Zorzela, Liliane

    2014-06-01

    Research indicates that the methods used to identify data for systematic reviews of adverse effects may need to differ from other systematic reviews. To compare search methods in systematic reviews of adverse effects with other reviews. The search methodologies in 849 systematic reviews of adverse effects were compared with other reviews. Poor reporting of search strategies is apparent in both systematic reviews of adverse effects and other types of systematic reviews. Systematic reviews of adverse effects are less likely to restrict their searches to MEDLINE or include only randomised controlled trials (RCTs). The use of other databases is largely dependent on the topic area and the year the review was conducted, with more databases searched in more recent reviews. Adverse effects search terms are used by 72% of reviews and despite recommendations only two reviews report using floating subheadings. The poor reporting of search strategies in systematic reviews is universal, as is the dominance of searching MEDLINE. However, reviews of adverse effects are more likely to include a range of study designs (not just RCTs) and search beyond MEDLINE. © 2014 Crown Copyright.

  2. Systematic assembly homogenization and local flux reconstruction for nodal method calculations of fast reactor power distributions

    International Nuclear Information System (INIS)

    Dorning, J.J.

    1991-01-01

    A simultaneous pin lattice cell and fuel bundle homogenization theory has been developed for use with nodal diffusion calculations of practical reactors. The theoretical development of the homogenization theory, which is based on multiple-scales asymptotic expansion methods carried out through fourth order in a small parameter, starts from the transport equation and systematically yields: a cell-homogenized bundled diffusion equation with self-consistent expressions for the cell-homogenized cross sections and diffusion tensor elements; and a bundle-homogenized global reactor diffusion equation with self-consistent expressions for the bundle-homogenized cross sections and diffusion tensor elements. The continuity of the angular flux at cell and bundle interfaces also systematically yields jump conditions for the scaler flux or so-called flux discontinuity factors on the cell and bundle interfaces in terms of the two adjacent cell or bundle eigenfunctions. The expressions required for the reconstruction of the angular flux or the 'de-homogenization' theory were obtained as an integral part of the development; hence the leading order transport theory angular flux is easily reconstructed throughout the reactor including the regions in the interior of the fuel bundles or computational nodes and in the interiors of the pin lattice cells. The theoretical development shows that the exact transport theory angular flux is obtained to first order from the whole-reactor nodal diffusion calculations, done using the homogenized nuclear data and discontinuity factors, is a product of three computed quantities: a ''cell shape function''; a ''bundle shape function''; and a ''global shape function''. 10 refs

  3. Current-based detection of nonlocal spin transport in graphene for spin-based logic applications

    Science.gov (United States)

    Wen, Hua; Zhu, Tiancong; Luo, Yunqiu Kelly; Amamou, Walid; Kawakami, Roland K.

    2014-05-01

    Graphene has been proposed for novel spintronic devices due to its robust and efficient spin transport properties at room temperature. Some of the most promising proposals require current-based readout for integration purposes, but the current-based detection of spin accumulation has not yet been developed. In this work, we demonstrate current-based detection of spin transport in graphene using a modified nonlocal geometry. By adding a variable shunt resistor in parallel to the nonlocal voltmeter, we are able to systematically cross over from the conventional voltage-based detection to current-based detection. As the shunt resistor is reduced, the output current from the spin accumulation increases as the shunt resistance drops below a characteristic value R*. We analyze this behavior using a one-dimensional drift-diffusion model, which accounts well for the observed behavior. These results provide the experimental and theoretical foundation for current-based detection of nonlocal spin transport.

  4. Spent nuclear fuel and high level radioactive waste transportation. White paper

    International Nuclear Information System (INIS)

    1985-06-01

    The High-Level Radioactive Waste Committee of the Western Interstate Energy Board has been involved in a year-long cooperative project with the US Department of Energy (DOE) to develop an information base on the transportation of spent nuclear fuel and high-level radioactive waste (HLW) so that western states can be constructive and informed participants in the repository program under the Nuclear Waste Policy Act (NWPA). The historical safety record of transportation of HLW and spent fuel is excellent; no release of these radioactive materials has ever occurred during transportation. Projected shipments under the NWPA will, however, greatly exceed current shipments in the US. For example, over the past five years, 119 metric tons of civilian spent fuel have been shipped in this country, while shipments to the first and second repository are each expected to peak at 3000 metric tons per year. The Committee believes that the successful development and operation of a national HLW/spent fuel transportation system can best be accomplished through an open process based on the common sense approach of taking all reasonable measures to minimize public risk and performing whatever actions are reasonably required to promote public acceptance. Therefore, the Committee recommends that the Department of Energy further the goals of the NWPA by developing a Comprehensive Transportation Plan which adopts a systematic, comprehensive, and integrated approach to resolving all spent fuel and HLW transportation issues in a timely manner. The suggested scope of such a plan is discussed in this White paper. Many of the suggested elements of such a plan are similar to those being developed by the Department of energy for inclusion in the Department's Transportation Institutional Plan

  5. In-Plane Magnetic Field Effect on the Transport Properties in a Quasi-3D Quantum Well Structure

    International Nuclear Information System (INIS)

    Brooks, J.; Clark, R.; Lumpkin, N.; O'Brien, J.; Reno, J.; Simmons, J.; Wang, Z.; Zhang, B.

    1999-01-01

    The transport properties of a quasi-three-dimensional, 200 layer quantum well structure are investigated at integer filling in the quantum Hall state. We find that the transverse magnetoresistance R xx , the Hall resistance R xy , and the vertical resistance R zz all follow a similar behavior with both temperature and in-plane magnetic field. A general feature of the influence of increasing in-plane field B in is that the Hall conductance quantization first improves, but above a characteristic value B C in , the quantization is systematically removed. We consider the interplay of the chid edge state transport and the bulk (quantum Hall) transport properties. This mechanism may arise from the competition of the cyclotron energy with the superlattice band structure energies. A comparison of the resuIts with existing theories of the chiral edge state transport with in-plane field is also discussed

  6. Investigating water transport through the xylem network in vascular plants.

    Science.gov (United States)

    Kim, Hae Koo; Park, Joonghyuk; Hwang, Ildoo

    2014-04-01

    Our understanding of physical and physiological mechanisms depends on the development of advanced technologies and tools to prove or re-evaluate established theories, and test new hypotheses. Water flow in land plants is a fascinating phenomenon, a vital component of the water cycle, and essential for life on Earth. The cohesion-tension theory (CTT), formulated more than a century ago and based on the physical properties of water, laid the foundation for our understanding of water transport in vascular plants. Numerous experimental tools have since been developed to evaluate various aspects of the CTT, such as the existence of negative hydrostatic pressure. This review focuses on the evolution of the experimental methods used to study water transport in plants, and summarizes the different ways to investigate the diversity of the xylem network structure and sap flow dynamics in various species. As water transport is documented at different scales, from the level of single conduits to entire plants, it is critical that new results be subjected to systematic cross-validation and that findings based on different organs be integrated at the whole-plant level. We also discuss the functional trade-offs between optimizing hydraulic efficiency and maintaining the safety of the entire transport system. Furthermore, we evaluate future directions in sap flow research and highlight the importance of integrating the combined effects of various levels of hydraulic regulation.

  7. Transport properties in a monolayer graphene modulated by the realistic magnetic field and the Schottky metal stripe

    Science.gov (United States)

    Lu, Jian-Duo; Li, Yun-Bao; Liu, Hong-Yu; Peng, Shun-Jin; Zhao, Fei-Xiang

    2016-09-01

    Based on the transfer-matrix method, a systematic investigation of electron transport properties is done in a monolayer graphene modulated by the realistic magnetic field and the Schottky metal stripe. The strong dependence of the electron transmission and the conductance on the incident angle of carriers is clearly seen. The height, position as well as width of the barrier also play an important role on the electron transport properties. These interesting results are very useful for understanding the tunneling mechanism in the monolayer graphene and helpful for designing the graphene-based electrical device modulated by the realistic magnetic field and the electrical barrier.

  8. Transport and Retention of Carboxymethylcellulose-Modified Carbon Nanotube-Magnetite Nanohybrids in Water-Saturated Porous Media

    Science.gov (United States)

    Wang, D.; Su, C.

    2017-12-01

    Carbon-metal oxide nanohybrids (NHs) are increasingly recognized as the next-generation, promising group of nanomaterials for solving emerging environmental issues and challenges. This research, for the first time, systematically explored the transport and retention of the multifunctional carbon nanotube-magnetite (CNT-Fe3O4) NHs in water-saturated porous media under environmentally relevant physicochemical conditions. An environment-benign macromolecule, carboxymethylcellulose (CMC), was employed to stabilize the NHs. Classical Derjaguin-Landau-Verwey-Overbeek (DLVO) theory and colloid transport model were used to describe the transport and retention of the NHs. Our results showed that transport of the magnetic CNT-Fe3O4 NHs was lower than that of the parent CNT due to greater aggregation (induced by magnetic attraction) during transport. The DLVO theory well-interpreted the NHs' transport; and secondary minimum played dominant roles in NHs' retention. A novel transport feature, an initial low and following sharp peaks occurred frequently in the NHs' breakthrough curves; and the magnitude and location of both transport peaks varied with different experimental conditions due to the interplay between variability of the fluid viscosity and aggregation-dispersion nature of the NHs. Very promisingly, the estimated maximum transport distance of NHs using the Tufenkji-Elimelech equation ranged between 0.38-46 m, supporting the feasibility of employing the magnetically recyclable CNT-Fe3O4 NHs for in-situ nanoremediation of contaminated soils, sediment aquifers, and groundwater.

  9. The iFlow modelling framework v2.4 : A modular idealized process-based model for flow and transport in estuaries

    NARCIS (Netherlands)

    Dijkstra, Y.M.; Brouwer, R.L.; Schuttelaars, H.M.; Schramkowski, G.P.

    2017-01-01

    The iFlow modelling framework is a width-averaged model for the systematic analysis of the water motion and sediment transport processes in estuaries and tidal rivers. The distinctive solution method, a mathematical perturbation method, used in the model allows for identification of the effect of

  10. Systematic study of transport via surface and bulk states in Bi2Te3 topological insulator

    Science.gov (United States)

    de Castro, S.; Peres, M. L.; Chitta, V. A.; Gratens, X.; Soares, D. A. W.; Fornari, C. I.; Rappl, P. H. O.; Abramof, E.; Oliveira, N. F., Jr.

    2016-07-01

    We performed magnetoresistance measurements on Bi2Te3 thin film in the temperature range of T = 1.2-4.0 K and for magnetic fields up to 2 T. The curves exhibited anomalous behavior for temperatures below 4.0 K. Different temperature intervals revealed electrical transport through different conductive channels with clear signatures of weak antilocalization. The magnetoresistance curves were explained using the Hikami-Larkin-Nagaoka model and the 2D Dirac modified model. The comparison between the parameters obtained from the two models revealed the transport via topological surface states and bulk states. In addition, a superconductive like transition is observed for the lowest temperatures and we suggest that this effect can be originated from the misfit dislocations caused by strain, giving rise to a superconductive channel between the interface of the film and the substrate.

  11. Information management and collection for U.S. DOE's packaging and transportation needs in the '90's

    International Nuclear Information System (INIS)

    Wheeler, T.A.; Luna, R.E.; McClure, J.D.; Quinn, G.

    1993-01-01

    The Transportation Assessment and Integration (TRAIN) Project (US DOE 1992) was established to provide a systematic approach to identify the problems and needs that will affect the capability of the United States Department of Energy (US DOE) to provide itself with cost-effective, efficient, and coordinated transportation services during the 1990s. Eight issue areas were identified to be included in the TRAIN Project, with one principal investigator assigned to each. The eight areas are as follows: 1) Packaging and Transportation Needs (PATN) in the 1990s; 2) Institutional and Outreach Programs; 3) Regulatory Impacts on Transportation Management; 4) Traffic and Packaging Operations; 5) Research and Development Requirements; 6) Training Support; 7) Emergency Preparedness Requirements; and 8) US DOE-EM 561 Roles and Responsibilities. This paper focuses on the results of the PATN activity of TRAIN. The objective of PATN is to prepare the US DOE, in general, and US DOE-EM 561 (Environmental Restoration and Waste Management (EM), Office of Technology Development, Transportation) in particular, to respond to the transportation needs of program elements in the Department. One of the first tasks in evaluating these needs was to formulate the potential for transportation of radioactive materials in the next decade. (J.P.N.)

  12. Electric dipole moment in KH{sub 2}PO{sub 4} systematically modified by proton irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Jin Kweon, Jung; Lee, Cheol Eui [Department of Physics and Institute for Nano Science, Korea University, Seoul 136-713 (Korea, Republic of); Noh, S. J.; Kim, H. S. [Department of Applied Physics, Dankook University, Yongin 448-701 (Korea, Republic of)

    2012-01-01

    We have carried out an impedance spectroscopy study on a series of proton-irradiated KH{sub 2}PO{sub 4} (KDP) systems. A systematic modification was observed in the transverse dipole moment of the proton-irradiated KDP systems, associated with hydrogen-ion displacements, as obtained from dielectric constant measurements by using a mean-field approximation. Besides, intercorrelation of the charge transport with the dielectric properties was revealed, both having closely to do with the hydrogen-bond modification.

  13. Changes of peritoneal transport parameters with time on dialysis: assessment with sequential peritoneal equilibration test.

    Science.gov (United States)

    Waniewski, Jacek; Antosiewicz, Stefan; Baczynski, Daniel; Poleszczuk, Jan; Pietribiasi, Mauro; Lindholm, Bengt; Wankowicz, Zofia

    2017-10-27

    Sequential peritoneal equilibration test (sPET) is based on the consecutive performance of the peritoneal equilibration test (PET, 4-hour, glucose 2.27%) and the mini-PET (1-hour, glucose 3.86%), and the estimation of peritoneal transport parameters with the 2-pore model. It enables the assessment of the functional transport barrier for fluid and small solutes. The objective of this study was to check whether the estimated model parameters can serve as better and earlier indicators of the changes in the peritoneal transport characteristics than directly measured transport indices that depend on several transport processes. 17 patients were examined using sPET twice with the interval of about 8 months (230 ± 60 days). There was no difference between the observational parameters measured in the 2 examinations. The indices for solute transport, but not net UF, were well correlated between the examinations. Among the estimated parameters, a significant decrease between the 2 examinations was found only for hydraulic permeability LpS, and osmotic conductance for glucose, whereas the other parameters remained unchanged. These fluid transport parameters did not correlate with D/P for creatinine, although the decrease in LpS values between the examinations was observed mostly for patients with low D/P for creatinine. We conclude that changes in fluid transport parameters, hydraulic permeability and osmotic conductance for glucose, as assessed by the pore model, may precede the changes in small solute transport. The systematic assessment of fluid transport status needs specific clinical and mathematical tools beside the standard PET tests.

  14. Potential spin-polarized transport in gold-doped armchair graphene nanoribbons

    Energy Technology Data Exchange (ETDEWEB)

    Srivastava, Pankaj, E-mail: pankajs@iiitm.ac.in [Nanomaterials Research Group, ABV-Indian Institute of Information Technology and Management (IIITM), Gwalior 474015, MP (India); Dhar, Subhra [Nanomaterials Research Group, ABV-Indian Institute of Information Technology and Management (IIITM), Gwalior 474015, MP (India); Jaiswal, Neeraj K. [Discipline of Physics, PDPM-Indian Institute of Information Technology, Design and Manufacturing (IIITDM), Jabalpur 482005 (India)

    2015-04-17

    Based on NEGF-DFT computations, systematic investigation of electronic, magnetic and transport properties of AGNRs are done by employing Au through different doping mechanisms. Remarkable Au–AGNR bonding is observed in case of substitution due to the presence of impurity at the edges. Both substitution and adsorption of Au on AGNR surface induce significant changes in the electronic spin transport of the sp{sup 2} hybridized carbon sheets. AGNRs are semiconducting with lower total energy for the FM configuration, and the I–V characteristics reveal semiconductor to metal transition of Au-doped AGNR. The spin injection is voltage controlled in all the investigated Au-doped AGNRs. - Highlights: • Edge Au-substitution promotes semiconductor–metal transition in AGNR. • NDR due to bias-dependent transmission in Au-substituted AGNRs. • Voltage controlled spin injection in all investigated Au-doped AGNRs. • Strong spin polarization occurs at 0.5 V in Au-hole adsorbed AGNRs.

  15. An overview of systematic review.

    Science.gov (United States)

    Baker, Kathy A; Weeks, Susan Mace

    2014-12-01

    Systematic review is an invaluable tool for the practicing clinician. A well-designed systematic review represents the latest and most complete information available on a particular topic or intervention. This article highlights the key elements of systematic review, what it is and is not, and provides an overview of several reputable organizations supporting the methodological development and conduct of systematic review. Important aspects for evaluating the quality of a systematic review are also included. Copyright © 2014 American Society of PeriAnesthesia Nurses. Published by Elsevier Inc. All rights reserved.

  16. Comprehensive understandings of energy confinement in LHD plasmas through extensive application of the integrated transport analysis suite

    International Nuclear Information System (INIS)

    Yokoyama, M.; Seki, R.; Suzuki, C.; Ida, K.; Osakabe, M.; Satake, S.; Yamada, H.; Murakami, S.

    2014-10-01

    The integrated transport analysis suite, TASK3D-a, has enhanced energy transport analyses in LHD. It has clearly elucidated (1) the systematic dependence of ion and electron energy confinement on wide variation of plasma parameters, and (2) statistically-derived fitting expressions for the ion and electron heat diffusivities (χ i and χ e ), separately, taking also those radial-profile information into account. In particular, the latter approach can outstrip the conventional scaling laws for the global confinement time (τ E ) in terms of its considerations on profiles (temperature, density, heating depositions etc.). This has been made possible with the analysis database accumulated by the extensive application of the integrated transport analysis suite to experiment data. In this proceeding, TASK3D-a analysis-database for high-ion-temperature (high-T i ) plasmas in LHD (Large Helical Device) are exemplified. This approach should be applicable to any other combinations of integrated transport analysis suites and fusion experiments. (author)

  17. Study of quiet turbofan STOL aircraft for short haul transportation

    Science.gov (United States)

    Higgins, T. P.; Stout, E. G.; Sweet, H. S.

    1973-01-01

    Conceptual designs of Quiet Turbofan STOL Short-Haul Transport Aircraft for the mid-1980 time period are developed and analyzed to determine their technical, operational, and economic feasibility. A matrix of aircraft using various high-lift systems and design parameters are considered. Variations in aircraft characteristics, airport geometry and location, and operational techniques are analyzed systematically to determine their effects on the market, operating economics, and community acceptance. In these studies, the total systems approach is considered to be critically important in analyzing the potential of STOL aircraft to reduce noise pollution and alleviate the increasing air corridor and airport congestion.

  18. Charge transport in amorphous organic semiconductors

    Energy Technology Data Exchange (ETDEWEB)

    Lukyanov, Alexander

    2011-03-15

    Organic semiconductors with the unique combination of electronic and mechanical properties may offer cost-effective ways of realizing many electronic applications, e. g. large-area flexible displays, printed integrated circuits and plastic solar cells. In order to facilitate the rational compound design of organic semiconductors, it is essential to understand relevant physical properties e. g. charge transport. This, however, is not straightforward, since physical models operating on different time and length scales need to be combined. First, the material morphology has to be known at an atomistic scale. For this atomistic molecular dynamics simulations can be employed, provided that an atomistic force field is available. Otherwise it has to be developed based on the existing force fields and first principle calculations. However, atomistic simulations are typically limited to the nanometer length- and nanosecond time-scales. To overcome these limitations, systematic coarse-graining techniques can be used. In the first part of this thesis, it is demonstrated how a force field can be parameterized for a typical organic molecule. Then different coarse-graining approaches are introduced together with the analysis of their advantages and problems. When atomistic morphology is available, charge transport can be studied by combining the high-temperature Marcus theory with kinetic Monte Carlo simulations. The approach is applied to the hole transport in amorphous films of tris(8- hydroxyquinoline)aluminium (Alq{sub 3}). First the influence of the force field parameters and the corresponding morphological changes on charge transport is studied. It is shown that the energetic disorder plays an important role for amorphous Alq{sub 3}, defining charge carrier dynamics. Its spatial correlations govern the Poole-Frenkel behavior of the charge carrier mobility. It is found that hole transport is dispersive for system sizes accessible to simulations, meaning that calculated

  19. A Bingham-plastic model for fluid mud transport under waves and currents

    Science.gov (United States)

    Liu, Chun-rong; Wu, Bo; Huhe, Ao-de

    2014-04-01

    Simplified equations of fluid mud motion, which is described as Bingham-Plastic model under waves and currents, are presented by order analysis. The simplified equations are non-linear ordinary differential equations which are solved by hybrid numerical-analytical technique. As the computational cost is very low, the effects of wave current parameters and fluid mud properties on the transportation velocity of the fluid mud are studied systematically. It is found that the fluid mud can move toward one direction even if the shear stress acting on the fluid mud bed is much smaller than the fluid mud yield stress under the condition of wave and current coexistence. Experiments of the fluid mud motion under current with fluctuation water surface are carried out. The fluid mud transportation velocity predicted by the presented mathematical model can roughly match that measured in experiments.

  20. Polarization-induced transport in organic field-effect transistors: the role of ferroelectric dielectrics

    Science.gov (United States)

    Guha, Suchismita; Laudari, Amrit

    2017-08-01

    The ferroelectric nature of polymer ferroelectrics such as poly(vinylidene fluoride) (PVDF) has been known for over 45 years. However, its role in interfacial transport in organic/polymeric field-effect transistors (FETs) is not that well understood. Dielectrics based on PVDF and its copolymers are a perfect test-bed for conducting transport studies where a systematic tuning of the dielectric constant with temperature may be achieved. The charge transport mechanism in an organic semiconductor often occurs at the intersection of band-like coherent motion and incoherent hopping through localized states. By choosing two small molecule organic semiconductors - pentacene and 6,13 bis(triisopropylsilylethynyl)pentacene (TIPS-pentacene) - along with a copolymer of PVDF (PVDF-TrFe) as the dielectric layer, the transistor characteristics are monitored as a function of temperature. A negative coefficient of carrier mobility is observed in TIPS-pentacene upwards of 200 K with the ferroelectric dielectric. In contrast, TIPS-pentacene FETs show an activated transport with non-ferroelectric dielectrics. Pentacene FETs, on the other hand, show a weak temperature dependence of the charge carrier mobility in the ferroelectric phase of PVDF-TrFE, which is attributed to polarization fluctuation driven transport resulting from a coupling of the charge carriers to the surface phonons of the dielectric layer. Further, we show that there is a strong correlation between the nature of traps in the organic semiconductor and interfacial transport in organic FETs, especially in the presence of a ferroelectric dielectric.

  1. Relating transport modeling to nanofiltration membrane fabrication: Navigating the permeability-selectivity trade-off in desalination pretreatment

    OpenAIRE

    Labban, Omar; Lienhard, John H

    2018-01-01

    Faced with a pressing need for membranes with a higher permeability and selectivity, the field of membrane technology can benefit from a systematic framework for designing membranes with the necessary physical characteristics. In this work, we present an approach through which transport modeling is employed in fabricating specialized nanofiltration membranes, that experimentally demonstrate enhanced selectivity. Specifically, the Donnan-Steric Pore Model with dielectric exclusion (DSPM-DE) is...

  2. Systematic Reviews in Sports Medicine.

    Science.gov (United States)

    DiSilvestro, Kevin J; Tjoumakaris, Fotios P; Maltenfort, Mitchell G; Spindler, Kurt P; Freedman, Kevin B

    2016-02-01

    The number of systematic reviews published in the orthopaedic literature has increased, and these reviews can help guide clinical decision making. However, the quality of these reviews can affect the reader's ability to use the data to arrive at accurate conclusions and make clinical decisions. To evaluate the methodological and reporting quality of systematic reviews and meta-analyses in the sports medicine literature to determine whether such reviews should be used to guide treatment decisions. The hypothesis was that many systematic reviews in the orthopaedic sports medicine literature may not follow the appropriate reporting guidelines or methodological criteria recommended for systematic reviews. Systematic review. All clinical sports medicine systematic reviews and meta-analyses from 2009 to 2013 published in The American Journal of Sports Medicine (AJSM), The Journal of Bone and Joint Surgery (JBJS), Arthroscopy, Sports Health, and Knee Surgery, Sports Traumatology, Arthroscopy (KSSTA) were reviewed and evaluated for level of evidence according to the guidelines from the Oxford Centre for Evidence-Based Medicine, for reporting quality according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, and for methodological quality according to the Assessment of Multiple Systematic Reviews (AMSTAR) tool. Analysis was performed by year and journal of publication, and the levels of evidence included in the systematic reviews were also analyzed. A total of 200 systematic reviews and meta-analyses were identified over the study period. Of these, 53% included evidence levels 4 and 5 in their analyses, with just 32% including evidence levels 1 and 2 only. There were significant differences in the proportion of articles with high levels of evidence (P Systematic reviews and meta-analyses in orthopaedics sports medicine literature relied on evidence levels 4 and 5 in 53% of studies over the 5-year study period. Overall, PRISMA and

  3. A systematic review of systematic reviews of homeopathy

    Science.gov (United States)

    Ernst, E

    2002-01-01

    Homeopathy remains one of the most controversial subjects in therapeutics. This article is an attempt to clarify its effectiveness based on recent systematic reviews. Electronic databases were searched for systematic reviews/meta-analysis on the subject. Seventeen articles fulfilled the inclusion/exclusion criteria. Six of them related to re-analyses of one landmark meta-analysis. Collectively they implied that the overall positive result of this meta-analysis is not supported by a critical analysis of the data. Eleven independent systematic reviews were located. Collectively they failed to provide strong evidence in favour of homeopathy. In particular, there was no condition which responds convincingly better to homeopathic treatment than to placebo or other control interventions. Similarly, there was no homeopathic remedy that was demonstrated to yield clinical effects that are convincingly different from placebo. It is concluded that the best clinical evidence for homeopathy available to date does not warrant positive recommendations for its use in clinical practice. PMID:12492603

  4. NMTC/JAM, Simulates High Energy Nuclear Reactions and Nuclear-Meson Transport Processes

    International Nuclear Information System (INIS)

    Furihata, Shiori

    2002-01-01

    1 - Description of program or function: NMTC/JAM is an upgraded version of the code system NMTC/JAERI97. NMTC/JAERI97 simulates high energy nuclear reactions and nucleon-meson transport processes. It implements an intra-nuclear cascade model taking account of the in-medium nuclear effects and the pre-equilibrium calculation model based on the exciton one. For treating the nucleon transport process, the nucleon-nucleus cross sections are revised to those derived by the systematics of Pearlstein. Moreover, the level density parameter derived by Ignatyuk is included as a new option for particle evaporation calculation. A geometry package based on the Combinatorial Geometry with multi-array system and the importance sampling technique is implemented in the code. Tally function is also employed for obtaining such physical quantities as neutron energy spectra, heat deposition and nuclide yield without editing a history file. The code can simulate both the primary spallation reaction and the secondary particle transport in the intermediate energy region from 20 MeV to 3.5 GeV by the use of the Monte Carlo technique. The code has been employed in combination with the neutron-photon transport codes available to the energy region below 20 MeV for neutronics calculation of accelerator-based subcritical reactors, analyses of thick target spallation experimented and so on. 2 - Methods: High energy nuclear reactions induced by incident high energy protons, neutrons and pions are simulated with the Monte Carlo Method by the intra-nuclear nucleon-nucleon reaction probabilities based on an intra-nuclear nucleon cascade model followed by the particle evaporation including high energy fission process. Jet-Aa Microscopic transport model (JAM) is employed to simulate high energy nuclear reactions in the energy range of GeV. All reaction channels are taken into account in the JAM calculation. An intra-nuclear cascade model (ISOBAR code) taking account of the in-medium nuclear effects

  5. Transport of radioactive substances; Der Transport radioaktiver Stoffe

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2014-12-15

    The report on the transport of radioactive substances covers the following topics: facts on radioactive materials transport, safety of the transport of radioactive substances, legal regulations and guidelines: a multiform but consistent system, transport of nuclear fuels, safety during the transport of nuclear fuel, future transport of spent fuel elements and high-level radioactive wastes in Germany.

  6. Sediment transport by runoff on debris-mantled dryland hillslopes

    Science.gov (United States)

    Michaelides, Katerina; Martin, Gareth J.

    2012-09-01

    Hillslopes supply sediment to river channels, and therefore impact drainage basin functioning and evolution. The relationship between hillslope attributes and sediment flux forms the basis of geomorphic transport laws used to model the long-term topographic evolution of drainage basins, but their specific interactions during individual storm events are not well understood. Runoff-driven erosion of coarse particles, prevalent in dryland environments, presents a particular set of conditions for sediment transport that is poorly resolved in current models. In order to address this gap, we developed a particle-based, force-balance model for sheetwash sediment transport on coarse, debris-mantled hillslopes within a rainfall-runoff model. We use the model to examine how the interplay between hillslope attributes (gradient, length and grain size distribution) and runoff characteristics affects sediment transport, grain-size changes on the hillslope, and sediment supply to the slope base. The relationship between sediment flux and hillslope gradient was found to transition from linear above a threshold to sigmoidal depending on hillslope length, initial grain sizes, and runoff characteristics. Grain sizes supplied to the slope base vary in a complex manner with hillslope attributes but an overall coarsening of the hillslopes is found to occur with increasing gradient, corroborating previous findings from field measurements. Intense, short duration storms result in within-hillslope sediment redistribution and equifinality in sediment supply for different hillslope characteristics, which explain the lack of field evidence for any systematic relationships. Our model findings provide insights into hillslope responses to climatic forcing and have theoretical implications for modeling hillslope evolution in dry lands.

  7. Building waste management core indicators through Spatial Material Flow Analysis: Net recovery and transport intensity indexes

    International Nuclear Information System (INIS)

    Font Vivanco, David; Puig Ventosa, Ignasi; Gabarrell Durany, Xavier

    2012-01-01

    Highlights: ► Sustainability and proximity principles have a key role in waste management. ► Core indicators are needed in order to quantify and evaluate them. ► A systematic, step-by-step approach is developed in this study for their development. ► Transport may play a significant role in terms of environmental and economic costs. ► Policy action is required in order to advance in the consecution of these principles. - Abstract: In this paper, the material and spatial characterization of the flows within a municipal solid waste (MSW) management system are combined through a Network-Based Spatial Material Flow Analysis. Using this information, two core indicators are developed for the bio-waste fraction, the Net Recovery Index (NRI) and the Transport Intensity Index (TII), which are aimed at assessing progress towards policy-related sustainable MSW management strategies and objectives. The NRI approaches the capacity of a MSW management system for converting waste into resources through a systematic metabolic approach, whereas the TII addresses efficiency in terms of the transport requirements to manage a specific waste flow throughout the entire MSW management life cycle. Therefore, both indicators could be useful in assessing key MSW management policy strategies, such as the consecution of higher recycling levels (sustainability principle) or the minimization of transport by locating treatment facilities closer to generation sources (proximity principle). To apply this methodological approach, the bio-waste management system of the region of Catalonia (Spain) has been chosen as a case study. Results show the adequacy of both indicators for identifying those points within the system with higher capacity to compromise its environmental, economic and social performance and therefore establishing clear targets for policy prioritization. Moreover, this methodological approach permits scenario building, which could be useful in assessing the outcomes of

  8. Michigan transportation facts & figures : public transportation

    Science.gov (United States)

    2002-08-16

    This on-line document is part of a series, Transportation Facts & Figures, by the Michigan Department of Transportation (MDOT). The Public Transit section of Transportation Facts & Figures cover such topics as intercity bus service, intercity rail se...

  9. Vertical Charge Transport and Negative Transconductance in Multilayer Molybdenum Disulfides.

    Science.gov (United States)

    Liu, Yuan; Guo, Jian; He, Qiyuan; Wu, Hao; Cheng, Hung-Chieh; Ding, Mengning; Shakir, Imran; Gambin, Vincent; Huang, Yu; Duan, Xiangfeng

    2017-09-13

    Negative transconductance (NTC) devices have been heavily investigated for their potential in low power logical circuit, memory, oscillating, and high-speed switching applications. Previous NTC devices are largely attributed to two working mechanisms: quantum mechanical tunneling, and mobility degradation at high electrical field. Herein we report a systematic investigation of charge transport in multilayer two-dimensional semiconductors (2DSCs) with optimized van der Waals contact and for the first time demonstrate NTC and antibipolar characteristics in multilayer 2DSCs (such as MoS 2 , WSe 2 ). By varying the measurement temperature, bias voltage, and body thickness, we found the NTC behavior can be attributed to a vertical potential barrier in the multilayer 2DSCs and the competing mechanisms between intralayer lateral transport and interlayer vertical transport, thus representing a new working mechanism for NTC operation. Importantly, this vertical potential barrier arises from inhomogeneous carrier distribution in 2DSC from the near-substrate region to the bulk region, which is in contrast to conventional semiconductors with homogeneous doping defined by bulk dopants. We further show that the unique NTC behavior can be explored for creating frequency doublers and phase shift keying circuits with only one transistor, greatly simplifying the circuit design compared to conventional technology.

  10. Comparing Collision Avoidance Systems of Different Type of Transportation Mode

    Directory of Open Access Journals (Sweden)

    Serkan ÖZDEMİR

    2016-11-01

    Full Text Available Different modes of transportation are often used in our daily lives. Therefore, how safe these modes are commonly researched by researchers. Many models and methods are developed to avoid collision with the development of technology. This development is aimed to improving the safety of life and property. The technological developments also aim to reduce the minimum level of the human error. Technological devices developed to prevent collision are applied in systematic way according to type of transportation mode. When comparatively examined, it is similar to each other technology used in different modes. In this respect, proposed model and methods are similar in general. These approaches are generally based on position of vehicles relative to each other and also rules have been developed taking into consideration the possibilities that may occur. Real-time sensors used to avoid collision in vehicles reduce risk of collision and provide significant achievements on behalf of avoiding collision. Besides this, it has been considered important a communication network between vehicles. As a result, the importance of the technological devices developed to ensure collision avoidance is increasing in our life. Thus, the study aims to explain and compare the methods, models and techniques used in the different transportation modes so as to avoid collision.

  11. Chamber transport

    International Nuclear Information System (INIS)

    Olson, Craig L.

    2001-01-01

    Heavy ion beam transport through the containment chamber plays a crucial role in all heavy ion fusion (HIF) scenarios. Here, several parameters are used to characterize the operating space for HIF beams; transport modes are assessed in relation to evolving target/accelerator requirements; results of recent relevant experiments and simulations of HIF transport are summarized; and relevant instabilities are reviewed. All transport options still exist, including (1) vacuum ballistic transport, (2) neutralized ballistic transport, and (3) channel-like transport. Presently, the European HIF program favors vacuum ballistic transport, while the US HIF program favors neutralized ballistic transport with channel-like transport as an alternate approach. Further transport research is needed to clearly guide selection of the most attractive, integrated HIF system

  12. Systematic text condensation

    DEFF Research Database (Denmark)

    Malterud, Kirsti

    2012-01-01

    To present background, principles, and procedures for a strategy for qualitative analysis called systematic text condensation and discuss this approach compared with related strategies.......To present background, principles, and procedures for a strategy for qualitative analysis called systematic text condensation and discuss this approach compared with related strategies....

  13. A diffusive ink transport model for lipid dip-pen nanolithography

    Science.gov (United States)

    Urtizberea, A.; Hirtz, M.

    2015-09-01

    Despite diverse applications, phospholipid membrane stacks generated by dip-pen nanolithography (DPN) still lack a thorough and systematic characterization that elucidates the whole ink transport process from writing to surface spreading, with the aim of better controlling the resulting feature size and resolution. We report a quantitative analysis and modeling of the dependence of lipid DPN features (area, height and volume) on dwell time and relative humidity. The ink flow rate increases with humidity in agreement with meniscus size growth, determining the overall feature size. The observed time dependence indicates the existence of a balance between surface spreading and the ink flow rate that promotes differences in concentration at the meniscus/substrate interface. Feature shape is controlled by the substrate surface energy. The results are analyzed within a modified model for the ink transport of diffusive inks. At any humidity the dependence of the area spread on the dwell time shows two diffusion regimes: at short dwell times growth is controlled by meniscus diffusion while at long dwell times surface diffusion governs the process. The critical point for the switch of regime depends on the humidity.Despite diverse applications, phospholipid membrane stacks generated by dip-pen nanolithography (DPN) still lack a thorough and systematic characterization that elucidates the whole ink transport process from writing to surface spreading, with the aim of better controlling the resulting feature size and resolution. We report a quantitative analysis and modeling of the dependence of lipid DPN features (area, height and volume) on dwell time and relative humidity. The ink flow rate increases with humidity in agreement with meniscus size growth, determining the overall feature size. The observed time dependence indicates the existence of a balance between surface spreading and the ink flow rate that promotes differences in concentration at the meniscus

  14. Common mental disorders in public transportation drivers in Lima, Peru.

    Science.gov (United States)

    Ruiz-Grosso, Paulo; Ramos, Mariana; Samalvides, Frine; Vega-Dienstmaier, Johann; Kruger, Hever

    2014-01-01

    Traffic related injuries are leading contributors to burden of disease worldwide. In developing countries a high proportion of them can be attributed to public transportation vehicles. Several mental disorders including alcohol and drug abuse, psychotic disorders, mental stress, productivity pressure, and low monetary income were found predictors of high rates of traffic related injuries in public transportation drivers. The goal of this study was to estimate the prevalence of common mental disorders in the population of public transportation drivers of buses and rickshaws in Lima, Peru. Cross sectional study. A sample of bus and rickshaw drivers was systematically selected from formal public transportation companies using a snowball approach. Participants completed self-administered questionnaires for assessing major depressive episode, anxiety symptoms, alcohol abuse, and burnout syndrome. Socio demographic information was also collected. The analyses consisted of descriptive measurement of outcomes taking into account both between and within cluster standard deviation (BCSD and WCSD). A total of 278 bus and 227 rickshaw drivers out of 25 companies agreed to participate in the study. BCSD for major depressive episode, anxiety symptoms and burnout syndrome was not found significant (p>0.05). The estimated prevalence of each variable was 13.7% (IC95%: 10.7-16.6%), 24.1% (IC95%: 19.4-28.8%) and 14.1% (IC95%: 10.8-17.4%) respectively. The estimated prevalence of alcohol abuse was 75.4% (IC95%: 69-81.7%, BCSD = 12.2%, WCSD = 41.9%, intra class correlation (ICC): 7.8%). Common mental disorders such as alcohol abuse, major depressive episode, anxiety symptoms and burnout syndrome presented higher rates in public transportation drivers than general population.

  15. Uniform Gauss-Weight Quadratures for Discrete Ordinate Transport Calculations

    International Nuclear Information System (INIS)

    Carew, John F.; Hu, Kai; Zamonsky, Gabriel

    2000-01-01

    Recently, a uniform equal-weight quadrature set, UE n , and a uniform Gauss-weight quadrature set, UG n , have been derived. These quadratures have the advantage over the standard level-symmetric LQ n quadrature sets in that the weights are positive for all orders,and the transport solution may be systematically converged by increasing the order of the quadrature set. As the order of the quadrature is increased,the points approach a uniform continuous distribution on the unit sphere,and the quadrature is invariant with respect to spatial rotations. The numerical integrals converge for continuous functions as the order of the quadrature is increased.The numerical characteristics of the UE n quadrature set have been investigated previously. In this paper, numerical calculations are performed to evaluate the application of the UG n quadrature set in typical transport analyses. A series of DORT transport calculations of the >1-MeV neutron flux have been performed for a set of pressure-vessel fluence benchmark problems. These calculations employed the UG n (n = 8, 12, 16, 24, and 32) quadratures and indicate that the UG n solutions have converged to within ∼0.25%. The converged UG n solutions are found to be comparable to the UE n results and are more accurate than the level-symmetric S 16 predictions

  16. Electron transport in gold colloidal nanoparticle-based strain gauges

    Science.gov (United States)

    Moreira, Helena; Grisolia, Jérémie; Sangeetha, Neralagatta M.; Decorde, Nicolas; Farcau, Cosmin; Viallet, Benoit; Chen, Ke; Viau, Guillaume; Ressier, Laurence

    2013-03-01

    A systematic approach for understanding the electron transport mechanisms in resistive strain gauges based on assemblies of gold colloidal nanoparticles (NPs) protected by organic ligands is described. The strain gauges were fabricated from parallel micrometer wide wires made of 14 nm gold (Au) colloidal NPs on polyethylene terephthalate substrates, elaborated by convective self-assembly. Electron transport in such devices occurs by inter-particle electron tunneling through the tunnel barrier imposed by the organic ligands protecting the NPs. This tunnel barrier was varied by changing the nature of organic ligands coating the nanoparticles: citrate (CIT), phosphines (BSPP, TDSP) and thiols (MPA, MUDA). Electro-mechanical tests indicate that only the gold NPs protected by phosphine and thiol ligands yield high gauge sensitivity. Temperature-dependent resistance measurements are explained using the ‘regular island array model’ that extracts transport parameters, i.e., the tunneling decay constant β and the Coulomb charging energy EC. This reveals that the Au@CIT nanoparticle assemblies exhibit a behavior characteristic of a strong-coupling regime, whereas those of Au@BSPP, Au@TDSP, Au@MPA and Au@MUDA nanoparticles manifest a weak-coupling regime. A comparison of the parameters extracted from the two methods indicates that the most sensitive gauges in the weak-coupling regime feature the highest β. Moreover, the EC values of these 14 nm NPs cannot be neglected in determining the β values.

  17. ORGANIZATION OF FREIGHT TRANSPORTATION IN UKRAINE IN THE REFORMATION CONDTIONS

    Directory of Open Access Journals (Sweden)

    L. V. Martseniuk

    2014-04-01

    Full Text Available Purpose. Each country of the former Soviet Union carries out railroad industry reformation according to different models depending on orienting points and the goals it establishes. All railway administrations have faced the problem of considerable reduction of freight and passenger transportation volumes, aging of main assets, lack of investments for their renovation. The purpose of the paper is the development of optimal management structure of freight cars in conditions of railway transport reformation. Methodology. The theoretical and methodological basis for research is a systematic analysis of problems of providing the competitiveness of the transport industry in the field of freight railway transportations, theoretical principles of economics in the production efficiency, market economics transformation and management of the national economy. Findings. The author has developed an improved mechanism for freight traffic management, which differs from the existing one by its adaptation to the conditions of industry being reformed and the organization of management companies. These companies together with the Ukrainian transport and logistics center centralize management of all freight cars of both domestic and foreign operating companies. Originality. Author presents the theoretical generalization and new solution of the scientific problem. It appears in the development of theoretical and methodological approaches to the management structure of the freight cars by operating companies in conditions of railway transport reforming through the management companies organization in Ukraine. The above mentioned companies will combine two types of activity – the commercial one and the cars repair of different property, it will reduce car turnover, stay time of rolling stock in the inoperative park and thereby improve the efficiency of freight transportations. Particularly, they will lease and have the right to dispose universal cars of domestic

  18. South Atlantic meridional transports from NEMO-based simulations and reanalyses

    Science.gov (United States)

    Mignac, Davi; Ferreira, David; Haines, Keith

    2018-02-01

    The meridional heat transport (MHT) of the South Atlantic plays a key role in the global heat budget: it is the only equatorward basin-scale ocean heat transport and it sets the northward direction of the global cross-equatorial transport. Its strength and variability, however, are not well known. The South Atlantic transports are evaluated for four state-of-the-art global ocean reanalyses (ORAs) and two free-running models (FRMs) in the period 1997-2010. All products employ the Nucleus for European Modelling of the Oceans (NEMO) model, and the ORAs share very similar configurations. Very few previous works have looked at ocean circulation patterns in reanalysis products, but here we show that the ORA basin interior transports are consistently improved by the assimilated in situ and satellite observations relative to the FRMs, especially in the Argo period. The ORAs also exhibit systematically higher meridional transports than the FRMs, which is in closer agreement with observational estimates at 35 and 11° S. However, the data assimilation impact on the meridional transports still greatly varies among the ORAs, leading to differences up to ˜ 8 Sv and 0.4 PW in the South Atlantic Meridional Overturning Circulation and the MHTs, respectively. We narrow this down to large inter-product discrepancies in the western boundary currents (WBCs) at both upper and deep levels explaining up to ˜ 85 % of the inter-product differences in MHT. We show that meridional velocity differences, rather than temperature differences, in the WBCs drive ˜ 83 % of this MHT spread. These findings show that the present ocean observation network and data assimilation schemes can be used to consistently constrain the South Atlantic interior circulation but not the overturning component, which is dominated by the narrow western boundary currents. This will likely limit the effectiveness of ORA products for climate or decadal prediction studies.

  19. Study of the exposures received by the persons involved in the transportation of radioactive materials

    International Nuclear Information System (INIS)

    Hamard, J.; Sousselier, Y.

    1983-01-01

    An important step in the optimization process applied to exposures in the field of the transport of radioactive materials is an accurate inventory of the exposures actually received by the workers. The results of this study underlines that nearly all the doses received are well below the threshold values for the classification of the workers as occasionally exposed and a fortiori as professionally exposed and consequently no personal monitoring should be necessary for them. Thus the inventory of exposures is somewhat difficult as the workers implied in the transport process are not classified as exposed workers and not subject to personnal or collective dosimetry. Therefore a good knowledge of the exposures received during the transport of irradiated fuels should require a systematic follow up of this kind of transport all along their route including a careful dosimetric monitoring of the workers taking part in the transport. On the other hand, the reduction of the doses obtained by increasing the mechanization involves very high monetary costs as compared to the reduction of the detriment. Perhaps a more important reduction of the exposures could be attained by a better protection in the cars or lorries used for the transport of categories A and B packages. But it seems that in the case of the transports, the optimization is applied mainly during the conception and the testing of the packages and only little progress will be possible without involving disproportionated monetary costs. 4 references, 10 tables

  20. Systematic study of the elliptic flow parameter using a transport approach

    International Nuclear Information System (INIS)

    Nasim, Md.; Mohanty, B.

    2015-01-01

    Elliptic flow parameter, v 2 is considered as a sensitive probe for early dynamics of the heavy-ion collision. In this work, we have discussed the effect of detector efficiency, procedure of centrality determination, effect of resonance decay and the procedure to correct event plane resolution on the measured v 2 by standard event plane method within the framework of a transport model. The measured value of v 2 depends on the efficiency in particle number counting by the detector. The effect of centrality determination is found to be negligible. The new method of event plane resolution correction for wide centrality bin yields results in v 2 values closer to the true value of the v 2 . The contributions from the resonance decay seems to decrease the value of v 2 of π and K within the ultra relativistic Quantum Molecular Dynamics (UrQMD) model based calculation. We also propose a procedure to correct for an event bias effect on v 2 arising while comparing the minimum bias collision centrality v 2 values for different multi-strange hadrons. Finally, we have presented a model based confirmation of the recently proposed relation between v 2 obtained using event plane method and scalar product method to the true value of v 2 . (author)

  1. An Electron-Transporting Thiazole-Based Polymer Synthesized Through Direct (Hetero)Arylation Polymerization.

    Science.gov (United States)

    Chávez, Patricia; Bulut, Ibrahim; Fall, Sadiara; Ibraikulov, Olzhas A; Chochos, Christos L; Bartringer, Jérémy; Heiser, Thomas; Lévêque, Patrick; Leclerc, Nicolas

    2018-05-25

    In this work, a new n -type polymer based on a thiazole-diketopyrrolopyrrole unit has been synthesized through direct (hetero)arylation polycondensation. The molar mass has been optimized by systematic variation of the the monomer concentration. Optical and electrochemical properties have been studied. They clearly suggested that this polymer possess a high electron affinity together with a very interesting absorption band, making it a good non-fullerene acceptor candidate. As a consequence, its charge transport and photovoltaic properties in a blend with the usual P3HT electron-donating polymer have been investigated.

  2. An Electron-Transporting Thiazole-Based Polymer Synthesized Through Direct (HeteroArylation Polymerization

    Directory of Open Access Journals (Sweden)

    Patricia Chávez

    2018-05-01

    Full Text Available In this work, a new n-type polymer based on a thiazole-diketopyrrolopyrrole unit has been synthesized through direct (heteroarylation polycondensation. The molar mass has been optimized by systematic variation of the the monomer concentration. Optical and electrochemical properties have been studied. They clearly suggested that this polymer possess a high electron affinity together with a very interesting absorption band, making it a good non-fullerene acceptor candidate. As a consequence, its charge transport and photovoltaic properties in a blend with the usual P3HT electron-donating polymer have been investigated.

  3. Transport container storage. Pt. 2

    International Nuclear Information System (INIS)

    Guenther, B.; Kuehn, H.D.; Schulz, E.

    1987-01-01

    In connection with mandatory licensing procedures and in the framework of quality control for serially produced containers from spheroidal graphite cast iron of quality grade GGG 40, destined to be used in the transport and storage of radioactive materials, each prototype and each production sample of a design is subjected to comprehensive destructive and non-destructive material tests. The data obtained are needed on the one hand to check whether specified, representative material characteristics are observed; on the other hand they are systematically evaluated to update knowledge and technical standards. The Federal Institute of Materials Research and Testing (BAM) has so far examined 528 individual containers (513 production samples and 15 prototypes) of wall thicknesses from 80 millimetres to 500 millimetres in this connection. It has turned out that the measures for quality assurance and quality control as substantiated by a concept of expertise definitely confirm the validity of component test results for production samples. (orig.) [de

  4. Do evidence summaries increase policy-makers' use of evidence from systematic reviews: A systematic review protocol.

    Science.gov (United States)

    Petkovic, Jennifer; Welch, Vivian; Tugwell, Peter

    2015-09-28

    Systematic reviews are important for decision-makers. They offer many potential benefits but are often written in technical language, are too long, and do not contain contextual details which makes them hard to use for decision-making. There are many organizations that develop and disseminate derivative products, such as evidence summaries, from systematic reviews for different populations or subsets of decision-makers. This systematic review will assess the effectiveness of systematic review summaries on increasing policymakers' use of systematic review evidence and to identify the components or features of these summaries that are most effective. We will include studies of policy-makers at all levels as well as health-system managers. We will include studies examining any type of "evidence summary," "policy brief," or other products derived from systematic reviews that present evidence in a summarized form. The primary outcomes are the following: (1) use of systematic review summaries decision-making (e.g., self-reported use of the evidence in policy-making, decision-making) and (2) policy-maker understanding, knowledge, and/or beliefs (e.g., changes in knowledge scores about the topic included in the summary). We will conduct a systematic review of randomized controlled trials (RCTs), non-randomized controlled trials (NRCTs), controlled before-after studies (CBA), and interrupted time series (ITS) studies. The results of this review will inform the development of future systematic review summaries to ensure that systematic review evidence is accessible to and used by policy-makers making health-related decisions.

  5. A Systematic Summary of Systematic Reviews on the Topic of the Anterior Cruciate Ligament

    Science.gov (United States)

    Anderson, Michael J.; Browning, William M.; Urband, Christopher E.; Kluczynski, Melissa A.; Bisson, Leslie J.

    2016-01-01

    Background: There has been a substantial increase in the amount of systematic reviews and meta-analyses published on the anterior cruciate ligament (ACL). Purpose: To quantify the number of systematic reviews and meta-analyses published on the ACL in the past decade and to provide an overall summary of this literature. Study Design: Systematic review; Level of evidence, 4. Methods: A systematic review of all ACL-related systematic reviews and meta-analyses published between January 2004 and September 2014 was performed using PubMed, MEDLINE, and the Cochrane Database. Narrative reviews and non-English articles were excluded. Results: A total of 1031 articles were found, of which 240 met the inclusion criteria. Included articles were summarized and divided into 17 topics: anatomy, epidemiology, prevention, associated injuries, diagnosis, operative versus nonoperative management, graft choice, surgical technique, fixation methods, computer-assisted surgery, platelet-rich plasma, rehabilitation, return to play, outcomes assessment, arthritis, complications, and miscellaneous. Conclusion: A summary of systematic reviews on the ACL can supply the surgeon with a single source for the most up-to-date synthesis of the literature. PMID:27047983

  6. Supplementary insurance as a switching cost for basic health insurance: Empirical results from the Netherlands.

    Science.gov (United States)

    Willemse-Duijmelinck, Daniëlle M I D; van de Ven, Wynand P M M; Mosca, Ilaria

    2017-10-01

    Nearly everyone with a supplementary insurance (SI) in the Netherlands takes out the voluntary SI and the mandatory basic insurance (BI) from the same health insurer. Previous studies show that many high-risks perceive SI as a switching cost for BI. Because consumers' current insurer provides them with a guaranteed renewability, SI is a switching cost if insurers apply selective underwriting to new applicants. Several changes in the Dutch health insurance market increased insurers' incentives to counteract adverse selection for SI. Tools to do so are not only selective underwriting, but also risk rating and product differentiation. If all insurers use the latter tools without selective underwriting, SI is not a switching cost for BI. We investigated to what extent insurers used these tools in the periods 2006-2009 and 2014-2015. Only a few insurers applied selective underwriting: in 2015, 86% of insurers used open enrolment for all their SI products, and the other 14% did use open enrolment for their most common SI products. As measured by our indicators, the proportion of insurers applying risk rating or product differentiation did not increase in the periods considered. Due to the fear of reputation loss insurers may have used 'less visible' tools to counteract adverse selection that are indirect forms of risk rating and product differentiation and do not result in switching costs. So, although many high-risks perceive SI as a switching cost, most insurers apply open enrolment for SI. By providing information to high-risks about their switching opportunities, the government could increase consumer choice and thereby insurers' incentives to invest in high-quality care for high-risks. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Analytic Theology as Systematic Theology

    OpenAIRE

    Crisp Oliver D.

    2017-01-01

    It is often said that analytic theology is not really systematic theology; it is something else entirely. However, specifying what this “something else” amounts to has proven a little more difficult. In this article I argue that analytic theology may be a species of systematic theology. I show that there is no agreed view on the nature of systematic theology amongst several leading practitioners of systematic theology by comparing the work of John Webster, Brian Gerrish, and Gordon Kaufman. I...

  8. Evaluation of criticality criteria for fissile class II packages in transportation

    International Nuclear Information System (INIS)

    Thomas, J.T.

    1976-01-01

    The nuclear criticality safety of packages in transportation is explored systematically by a surface density representation of reflected array criticality of air-spaced units. Typical perturbations to arrays are shown to be related analytically to the corresponding reactivity changes they produce. The reactivity change associated with the removal of three reflecting surfaces from a totally water reflected array is shown to depend upon the fissile material loading of the packages. For U(93.2) metal, the expected reactivity loss can range from 2 to 21%. Replacement of a three-sided reflector of water on a critical array by one of concrete results in a reactivity increase ranging from 0 to 6%. Mass limits established by criticality data for reflected arrays of air-spaced units can provide a minimum, uniform margin of safety, expressible in terms of reactivity, to more reliably specify subcriticality in transport. Mass limits less than those defined by air-spaced units in water-reflected arrays are unnecessary for Fissile Class II packages. (author)

  9. A low proportion of systematic reviews in physical therapy are registered: a survey of 150 published systematic reviews.

    Science.gov (United States)

    Oliveira, Crystian B; Elkins, Mark R; Lemes, Ítalo Ribeiro; de Oliveira Silva, Danilo; Briani, Ronaldo V; Monteiro, Henrique Luiz; Azevedo, Fábio Mícolis de; Pinto, Rafael Zambelli

    Systematic reviews provide the best evidence about the effectiveness of healthcare interventions. Although systematic reviews are conducted with explicit and transparent methods, discrepancies might occur between the protocol and the publication. To estimate the proportion of systematic reviews of physical therapy interventions that are registered, the methodological quality of (un)registered systematic reviews and the prevalence of outcome reporting bias in registered systematic reviews. A random sample of 150 systematic reviews published in 2015 indexed on the PEDro database. We included systematic reviews written in English, Italian, Portuguese and Spanish. A checklist for assessing the methodological quality of systematic reviews tool was used. Relative risk was calculated to explore the association between meta-analysis results and the changes in the outcomes. Twenty-nine (19%) systematic reviews were registered. Funding and publication in a journal with an impact factor higher than 5.0 were associated with registration. Registered systematic reviews demonstrated significantly higher methodological quality (median=8) than unregistered systematic reviews (median=5). Nine (31%) registered systematic reviews demonstrated discrepancies between protocol and publication with no evidence that such discrepancies were applied to favor the statistical significance of the intervention (RR=1.16; 95% CI: 0.63-2.12). A low proportion of systematic reviews in the physical therapy field are registered. The registered systematic reviews showed high methodological quality without evidence of outcome reporting bias. Further strategies should be implemented to encourage registration. Copyright © 2017 Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia. Publicado por Elsevier Editora Ltda. All rights reserved.

  10. Intelligent Transport Systems in the Management of Road Transportation

    Science.gov (United States)

    Kalupová, Blanka; Hlavoň, Ivan

    2016-11-01

    Extension of European Union causes increase of free transfer of people and goods. At the same time they raised the problems associated with the transport, e.g. congestion and related accidents on roads, air traffic delays and more. To increase the efficiency and safety of transport, the European Commission supports the introduction of intelligent transport systems and services in all transport sectors. Implementation of intelligent transport systems and services in the road transport reduces accident frequency, increases the capacity of existing infrastructure and reduces congestions. Use of toll systems provides resources needed for the construction and operation of a new road network, improves public transport, cycling transport and walking transport, and also their multimodal integration with individual car transport.

  11. ANALYISIS OF TRANSPORTATION SYSTEMS AND TRANSPORTATION POLICIES IN TURKEY

    Directory of Open Access Journals (Sweden)

    Ali Payıdar AKGÜNGÖR

    2004-03-01

    Full Text Available Transportation systems have to be considered and analysed as a whole while transportation demand, becoming as a natural outcome of socioeconomic and socio-cultural structure, is being evaluated. It is desired that transportation system, which will be selected for both passenger and freight transport, should be rapid, economic, safe, causing least harm to environment and appropriate for the conditions of a country. However, it is difficult for a transportation system to have all these properties. Every transportation system has advantages and disadvantages over each other. Therefore, comprehensive plans for future periods have to be prepared and how the sources of the country should be reasonably distributed among transportation systems must be investigated. Also, transportation plans have to be prepared to get coordinated operations among transportation systems while great investments are instituted in the entire country. There is no doubt that it is possible with combined transportation instead of concentration on one transportation system. Transportation policies in Turkey should be questioned since the level of highway transportation usage reaches to 95 % and level of sea transportation usage drops to less than 1 % in spite of being surrounded with sea in three sides of our land. In this paper, transportation systems and transportation policies in Turkey are evaluated in general and problems are analysed. Proposals are presented for the solutions of these problems.

  12. Investigating Systematic Errors of the Interstellar Flow Longitude Derived from the Pickup Ion Cutoff

    Science.gov (United States)

    Taut, A.; Berger, L.; Drews, C.; Bower, J.; Keilbach, D.; Lee, M. A.; Moebius, E.; Wimmer-Schweingruber, R. F.

    2017-12-01

    Complementary to the direct neutral particle measurements performed by e.g. IBEX, the measurement of PickUp Ions (PUIs) constitutes a diagnostic tool to investigate the local interstellar medium. PUIs are former neutral particles that have been ionized in the inner heliosphere. Subsequently, they are picked up by the solar wind and its frozen-in magnetic field. Due to this process, a characteristic Velocity Distribution Function (VDF) with a sharp cutoff evolves, which carries information about the PUI's injection speed and thus the former neutral particle velocity. The symmetry of the injection speed about the interstellar flow vector is used to derive the interstellar flow longitude from PUI measurements. Using He PUI data obtained by the PLASTIC sensor on STEREO A, we investigate how this concept may be affected by systematic errors. The PUI VDF strongly depends on the orientation of the local interplanetary magnetic field. Recently injected PUIs with speeds just below the cutoff speed typically form a highly anisotropic torus distribution in velocity space, which leads to a longitudinal transport for certain magnetic field orientation. Therefore, we investigate how the selection of magnetic field configurations in the data affects the result for the interstellar flow longitude that we derive from the PUI cutoff. Indeed, we find that the results follow a systematic trend with the filtered magnetic field angles that can lead to a shift of the result up to 5°. In turn, this means that every value for the interstellar flow longitude derived from the PUI cutoff is affected by a systematic error depending on the utilized magnetic field orientations. Here, we present our observations, discuss possible reasons for the systematic trend we discovered, and indicate selections that may minimize the systematic errors.

  13. Emergency transportation interventions for reducing adverse pregnancy outcomes in low- and middle-income countries: a systematic review protocol.

    Science.gov (United States)

    Ehiri, John; Alaofè, Halimatou; Asaolu, Ibitola; Chebet, Joy; Esu, Ekpereonne; Meremikwu, Martin

    2018-04-25

    Transportation interventions seek to decrease delay in reaching a health facility for emergency obstetric care and are, thus, believed to contribute to reductions in such adverse pregnancy and childbirth outcomes as maternal deaths, stillbirths, and neonatal mortality in low- and middle-income countries (LMICs). However, there is limited empirical evidence to support this hypothesis. The objective of the proposed review is to summarize and critically appraise evidence regarding the effect of emergency transportation interventions on outcomes of labor and delivery in LMICs. The following databases will be searched from inception to March 31, 2018: MEDLINE/PubMed, EMBASE, Web of Science, EBSCO (PsycINFO and CINAHL), the Cochrane Pregnancy and Child Birth Group's Specialized Register, and the Cochrane Central Register of Controlled Trials. We will search for studies in the grey literature through Google and Google Scholar. We will solicit unpublished reports from such relevant agencies as United Nations Fund for Population Activities (UNFPA), the World Health Organization (WHO), the United Nations Children's Fund (UNICEF), the United States Agency for International Development (USAID), and the United Kingdom Department for International Development (DfID) among others. Data generated from the search will be managed using Endnote Version 7. We will perform quantitative data synthesis if studies are homogenous in characteristics and provide adequate outcome data for meta-analysis. Otherwise, data will be synthesized, using the narrative synthesis approach. Among the many barriers that women in LMICs face in accessing life-saving interventions during labor and delivery, lack of access to emergency transportation is particularly important. This review will provide a critical summary of evidence regarding the impact of transportation interventions on outcomes of pregnancy and childbirth in LMICs. PROSPERO CRD42017080092.

  14. Survey and alignment of high energy physics accelerators and transport lines

    International Nuclear Information System (INIS)

    Ruland, R.E.

    1992-11-01

    This talk summarizes the survey and alignment processes of accelerators and transport lines and discusses the propagation of errors associated with these processes. The major geodetic principles governing the survey and alignment measurement space are revisited and their relationship to a lattice coordinate system shown. The paper continues with a broad overview about the activities involved in the step by step sequence from initial absolute alignment to final smoothing. Emphasis is given to the relative alignment of components, in particular to the importance of incorporating methods to remove residual systematic effects in surveying and alignment operations

  15. Guidelines for Computing Longitudinal Dynamic Stability Characteristics of a Subsonic Transport

    Science.gov (United States)

    Thompson, Joseph R.; Frank, Neal T.; Murphy, Patrick C.

    2010-01-01

    A systematic study is presented to guide the selection of a numerical solution strategy for URANS computation of a subsonic transport configuration undergoing simulated forced oscillation about its pitch axis. Forced oscillation is central to the prevalent wind tunnel methodology for quantifying aircraft dynamic stability derivatives from force and moment coefficients, which is the ultimate goal for the computational simulations. Extensive computations are performed that lead in key insights of the critical numerical parameters affecting solution convergence. A preliminary linear harmonic analysis is included to demonstrate the potential of extracting dynamic stability derivatives from computational solutions.

  16. Drug disposition and drug-drug interaction data in 2013 FDA new drug applications: a systematic review.

    Science.gov (United States)

    Yu, Jingjing; Ritchie, Tasha K; Mulgaonkar, Aditi; Ragueneau-Majlessi, Isabelle

    2014-12-01

    The aim of the present work was to perform a systematic review of drug metabolism, transport, pharmacokinetics, and DDI data available in the NDAs approved by the FDA in 2013, using the University of Washington Drug Interaction Database, and to highlight significant findings. Among 27 NMEs approved, 22 (81%) were well characterized with regard to drug metabolism, transport, or organ impairment, in accordance with the FDA drug interaction guidance (2012) and were fully analyzed in this review. In vitro, a majority of the NMEs were found to be substrates or inhibitors/inducers of at least one drug metabolizing enzyme or transporter. However, in vivo, only half (n = 11) showed clinically relevant drug interactions, with most related to the NMEs as victim drugs and CYP3A being the most affected enzyme. As perpetrators, the overall effects for NMEs were much less pronounced, compared with when they served as victims. In addition, the pharmacokinetic evaluation in patients with hepatic or renal impairment provided useful information for further understanding of the drugs' disposition. Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics.

  17. Experimental study on interfacial area transport in downward two-phase flow

    Science.gov (United States)

    Wang, Guanyi

    In view of the importance of two group interfacial area transport equations and lack of corresponding accurate downward flow database that can reveal two group interfacial area transport, a systematic database for adiabatic, air-water, vertically downward two-phase flow in a round pipe with inner diameter of 25.4 mm was collected to gain an insight of interfacial structure and provide benchmarking data for two-group interfacial area transport models. A four-sensor conductivity probe was used to measure the local two phase flow parameters and data was collected with data sampling frequency much higher than conventional data sampling frequency to ensure the accuracy. Axial development of local flow parameter profiles including void fraction, interfacial area concentration, and Sauter mean diameter were presented. Drastic inter-group transfer of void fraction and interfacial area was observed at bubbly to slug transition flow. And the wall peaked interfacial area concentration profiles were observed in churn-turbulent flow. The importance of local data about these phenomenon on flow structure prediction and interfacial area transport equation benchmark was analyzed. Bedsides, in order to investigate the effect of inlet conditions, all experiments were repeated after installing the flow straightening facility, and the results were briefly analyzed. In order to check the accuracy of current data, the experiment results were cross-checked with rotameter measurement as well as drift-flux model prediction, the averaged error is less than 15%. Current models for two-group interfacial area transport equation were evaluated using these data. The results show that two-group interfacial area transport equations with current models can predict most flow conditions with error less than 20%, except some bubbly to slug transition flow conditions and some churn-turbulent flow conditions. The disagreement between models and experiments could result from underestimate of inter

  18. Optimation of Operation System Integration between Main and Feeder Public Transport (Case Study: Trans Jakarta-Kopaja Bus Services)

    Science.gov (United States)

    Miharja, M.; Priadi, Y. N.

    2018-05-01

    Promoting a better public transport is a key strategy to cope with urban transport problems which are mostly caused by a huge private vehicle usage. A better public transport service quality not only focuses on one type of public transport mode, but also concerns on inter modes service integration. Fragmented inter mode public transport service leads to a longer trip chain as well as average travel time which would result in its failure to compete with a private vehicle. This paper examines the optimation process of operation system integration between Trans Jakarta Bus as the main public transport mode and Kopaja Bus as feeder public transport service in Jakarta. Using scoring-interview method combined with standard parameters in operation system integration, this paper identifies the key factors that determine the success of the two public transport operation system integrations. The study found that some key integration parameters, such as the cancellation of “system setoran”, passenger get in-get out at official stop points, and systematic payment, positively contribute to a better service integration. However, some parameters such as fine system, time and changing point reliability, and information system reliability are among those which need improvement. These findings are very useful for the authority to set the right strategy to improve operation system integration between Trans Jakarta and Kopaja Bus services.

  19. Impacts of urbanization on national transport and road energy use: Evidence from low, middle and high income countries

    International Nuclear Information System (INIS)

    Poumanyvong, Phetkeo; Kaneko, Shinji; Dhakal, Shobhakar

    2012-01-01

    Few attempts have been made to investigate quantitatively and systematically the impact of urbanization on transport energy use for countries of different stages of economic development. This paper examines the influence of urbanization on national transport and road energy use for low, middle and high income countries during 1975–2005, using the Stochastic Impacts by Regression on Population, Affluence and Technology (STIRPAT) model. After controlling for population size, income per capita and the share of services in the economy, the main results suggest that urbanization influences national transport and road energy use positively. However, the magnitude of its influence varies among the three income groups. Changes in urbanization appear to have a greater impact on transport and road energy use in the high income group than in the other groups. Surprisingly, the urbanization elasticities of transport and road energy use in the middle income group are smaller than those of the low income group. This study not only sheds further light on the existing literature, but also provides policy makers with insightful information on the link between urbanization and transport energy use at the three different stages of development. - Highlights: ► Overall, urbanization increases national transport and road energy use. ► Urbanization elasticities of transport energy use differ across development stages. ► Urbanization elasticities in high-income group are higher than in other groups.

  20. Computational aspects of systematic biology.

    Science.gov (United States)

    Lilburn, Timothy G; Harrison, Scott H; Cole, James R; Garrity, George M

    2006-06-01

    We review the resources available to systematic biologists who wish to use computers to build classifications. Algorithm development is in an early stage, and only a few examples of integrated applications for systematic biology are available. The availability of data is crucial if systematic biology is to enter the computer age.

  1. Systematic errors in transport calculations of shear viscosity using the Green-Kubo formalism

    Science.gov (United States)

    Rose, J. B.; Torres-Rincon, J. M.; Oliinychenko, D.; Schäfer, A.; Petersen, H.

    2018-05-01

    The purpose of this study is to provide a reproducible framework in the use of the Green-Kubo formalism to extract transport coefficients. More specifically, in the case of shear viscosity, we investigate the limitations and technical details of fitting the auto-correlation function to a decaying exponential. This fitting procedure is found to be applicable for systems interacting both through constant and energy-dependent cross-sections, although this is only true for sufficiently dilute systems in the latter case. We find that the optimal fit technique consists in simultaneously fixing the intercept of the correlation function and use a fitting interval constrained by the relative error on the correlation function. The formalism is then applied to the full hadron gas, for which we obtain the shear viscosity to entropy ratio.

  2. Analysis of transport administrators and sustainable transport ...

    African Journals Online (AJOL)

    Analysis of transport administrators and sustainable transport development in Lagos, Ogun and Oyo States, Nigeria. ... A good transportation system planning and management is considered vital for ... EMAIL FULL TEXT EMAIL FULL TEXT

  3. Systematic Quality Work in Preschool

    Science.gov (United States)

    Sheridan, Sonja; Williams, Pia; Sandberg, Anette

    2013-01-01

    The purpose of this study was to investigate the meaning that Swedish preschool teachers ascribe to systematic quality work. In Sweden, all preschools are required to work systematically with quality issues. This involves several interdependent steps that follow each other in a specific order. Although the concept of systematic quality work might…

  4. Radiation Transport

    Energy Technology Data Exchange (ETDEWEB)

    Urbatsch, Todd James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-06-15

    We present an overview of radiation transport, covering terminology, blackbody raditation, opacities, Boltzmann transport theory, approximations to the transport equation. Next we introduce several transport methods. We present a section on Caseology, observing transport boundary layers. We briefly broach topics of software development, including verification and validation, and we close with a section on high energy-density experiments that highlight and support radiation transport.

  5. Development of micro-four-point probe in a scanning tunneling microscope for in situ electrical transport measurement.

    Science.gov (United States)

    Ge, Jian-Feng; Liu, Zhi-Long; Gao, Chun-Lei; Qian, Dong; Liu, Canhua; Jia, Jin-Feng

    2015-05-01

    Electrons at surface may behave differently from those in bulk of a material. Multi-functional tools are essential in comprehensive studies on a crystal surface. Here, we developed an in situ microscopic four-point probe (4PP) transport measurement system on the basis of a scanning tunneling microscope (STM). In particular, convenient replacement between STM tips and micro-4PPs enables systematic investigations of surface morphology, electronic structure, and electrical transport property of a same sample surface. Performances of the instrument are demonstrated with high-quality STM images, tunneling spectra, and low-noise electrical I-V characteristic curves of a single-layer FeSe film grown on a conductive SrTiO3 surface.

  6. Development of micro-four-point probe in a scanning tunneling microscope for in situ electrical transport measurement

    Energy Technology Data Exchange (ETDEWEB)

    Ge, Jian-Feng; Liu, Zhi-Long; Gao, Chun-Lei; Qian, Dong; Liu, Canhua, E-mail: canhualiu@sjtu.edu.cn, E-mail: jfjia@sjtu.edu.cn; Jia, Jin-Feng, E-mail: canhualiu@sjtu.edu.cn, E-mail: jfjia@sjtu.edu.cn [Key Laboratory of Artificial Structures and Quantum Control (Ministry of Education), Department of Physics and Astronomy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240 (China)

    2015-05-15

    Electrons at surface may behave differently from those in bulk of a material. Multi-functional tools are essential in comprehensive studies on a crystal surface. Here, we developed an in situ microscopic four-point probe (4PP) transport measurement system on the basis of a scanning tunneling microscope (STM). In particular, convenient replacement between STM tips and micro-4PPs enables systematic investigations of surface morphology, electronic structure, and electrical transport property of a same sample surface. Performances of the instrument are demonstrated with high-quality STM images, tunneling spectra, and low-noise electrical I-V characteristic curves of a single-layer FeSe film grown on a conductive SrTiO{sub 3} surface.

  7. Theoretical comparative studies on transport properties of pentacene, pentathienoacene, and 6,13-dichloropentacene.

    Science.gov (United States)

    Zhang, Xu; Yang, Xiaodi; Geng, Hua; Nan, Guangjun; Sun, Xingwen; Xi, Jinyang; Xu, Xin

    2015-05-05

    Pentacene derivative 6,13-dichloropentacene (DCP) is one of the latest additions to the family of organic semiconductors with a great potential for use in transistors. We carry out a detailed theoretical calculation for DCP, with systematical comparison to pentacene, pentathienoacene (PTA, the thiophene equivalent of pentacene), to gain insights in the theoretical design of organic transport materials. The charge transport parameters and carrier mobilities are investigated from the first-principles calculations, based on the widely used Marcus electron transfer theory and quantum nuclear tunneling model, coupled with random walk simulation. Molecular structure and the crystal packing type are essential to understand the differences in their transport behaviors. With the effect of molecule modification, significant one-dimensional π-stacks are found within the molecular layer in PTA and DCP crystals. The charge transport along the a-axis plays a dominant role for the carrier mobilities in the DCP crystal due to the strong transfer integrals within the a-axis. Pentacene shows a relatively large 3D mobility. This is attributed to the relatively uniform electronic couplings, which thus provides more transport pathways. PTA has a much smaller 3D mobility than pentacene and DCP for the obvious increase of the reorganization energy with the introduction of thiophene. It is found that PTA and DCP exhibit lower HOMO (highest occupied molecular orbital) levels and better environmental stability, indicating the potential applications in organic electronics. © 2015 Wiley Periodicals, Inc.

  8. Combinatorial theory of the semiclassical evaluation of transport moments. I. Equivalence with the random matrix approach

    Energy Technology Data Exchange (ETDEWEB)

    Berkolaiko, G., E-mail: berko@math.tamu.edu [Department of Mathematics, Texas A and M University, College Station, Texas 77843-3368 (United States); Kuipers, J., E-mail: Jack.Kuipers@physik.uni-regensburg.de [Institut für Theoretische Physik, Universität Regensburg, D-93040 Regensburg (Germany)

    2013-11-15

    To study electronic transport through chaotic quantum dots, there are two main theoretical approaches. One involves substituting the quantum system with a random scattering matrix and performing appropriate ensemble averaging. The other treats the transport in the semiclassical approximation and studies correlations among sets of classical trajectories. There are established evaluation procedures within the semiclassical evaluation that, for several linear and nonlinear transport moments to which they were applied, have always resulted in the agreement with random matrix predictions. We prove that this agreement is universal: any semiclassical evaluation within the accepted procedures is equivalent to the evaluation within random matrix theory. The equivalence is shown by developing a combinatorial interpretation of the trajectory sets as ribbon graphs (maps) with certain properties and exhibiting systematic cancellations among their contributions. Remaining trajectory sets can be identified with primitive (palindromic) factorisations whose number gives the coefficients in the corresponding expansion of the moments of random matrices. The equivalence is proved for systems with and without time reversal symmetry.

  9. The influence of sediment transport rate on the development of structure in gravel bed rivers

    Science.gov (United States)

    Ockelford, Annie; Rice, Steve; Powell, Mark; Reid, Ian; Nguyen, Thao; Tate, Nick; Wood, Jo

    2013-04-01

    Although adjustments of surface grain size are known to be strongly influenced by sediment transport rate little work has systematically explored how different transport rates can affect the development of surface structure in gravel bed rivers. Specifically, it has been well established that the transport of mixed sized sediments leads to the development of a coarser surface or armour layer which occurs over larger areas of the gravel bed. Armour layer development is known to moderate overall sediment transport rate as well as being extremely sensitive to changes in applied shear stress. However, during this armouring process a bed is created where, smaller gain scale changes, to the bed surface are also apparent such as the development of pebble clusters and imbricate structures. Although these smaller scale changes affect the overall surface grain size distribution very little their presence has the ability to significantly increase the surface stability and hence alter overall sediment transport rates. Consequently, the interplay between the moderation of transport rate as a function of surface coarsening at a larger scale and moderation of transport rate as a function of the development of structure on the bed surface at the smaller scale is complicated and warrants further investigation. During experiments a unimodal grain size distribution (σg = 1.30, D50 = 8.8mm) was exposed to 3 different levels of constant discharge that produced sediment transport conditions ranging from marginal transport to conditions approaching full mobility of all size fractions. Sediment was re-circulated during the experiments surface grain size distribution bed load and fractional transport rates were measured at a high temporal resolution such that the time evolution of the beds could be fully described. Discussion concentrates on analysing the effects of the evolving bed condition sediment transport rate (capacity) and transported grain size (competence). The outcome of this

  10. Common mental disorders in public transportation drivers in Lima, Peru.

    Directory of Open Access Journals (Sweden)

    Paulo Ruiz-Grosso

    Full Text Available BACKGROUND: Traffic related injuries are leading contributors to burden of disease worldwide. In developing countries a high proportion of them can be attributed to public transportation vehicles. Several mental disorders including alcohol and drug abuse, psychotic disorders, mental stress, productivity pressure, and low monetary income were found predictors of high rates of traffic related injuries in public transportation drivers. The goal of this study was to estimate the prevalence of common mental disorders in the population of public transportation drivers of buses and rickshaws in Lima, Peru. METHODOLOGY/PRINCIPAL FINDINGS: Cross sectional study. A sample of bus and rickshaw drivers was systematically selected from formal public transportation companies using a snowball approach. Participants completed self-administered questionnaires for assessing major depressive episode, anxiety symptoms, alcohol abuse, and burnout syndrome. Socio demographic information was also collected. The analyses consisted of descriptive measurement of outcomes taking into account both between and within cluster standard deviation (BCSD and WCSD. A total of 278 bus and 227 rickshaw drivers out of 25 companies agreed to participate in the study. BCSD for major depressive episode, anxiety symptoms and burnout syndrome was not found significant (p>0.05. The estimated prevalence of each variable was 13.7% (IC95%: 10.7-16.6%, 24.1% (IC95%: 19.4-28.8% and 14.1% (IC95%: 10.8-17.4% respectively. The estimated prevalence of alcohol abuse was 75.4% (IC95%: 69-81.7%, BCSD = 12.2%, WCSD = 41.9%, intra class correlation (ICC: 7.8%. CONCLUSION: Common mental disorders such as alcohol abuse, major depressive episode, anxiety symptoms and burnout syndrome presented higher rates in public transportation drivers than general population.

  11. Interfaces between transport and geological disposal systems for high level radioactive waste and spent nuclear fuel

    International Nuclear Information System (INIS)

    1994-09-01

    This document is an IAEA publication which identifies and discusses the interfaces and the interface requirements between high level waste, the waste transport system used for carriage of the waste to the disposal facility, and the high level waste disposal facility. The development of this document was prompted in part by the initiatives in various Member States to select, characterize and design the facilities for potential high level waste geological repositories. These initiatives have progressed to the point where an international document would be useful in calling attention to the need for establishing, in a systematic way, interfaces and interface requirements between the transport systems to be used and the waste disposal packages and geological repository. Refs, figs and tabs

  12. The IRSN experience feedback for the transport package design safety appraisals

    International Nuclear Information System (INIS)

    Sert, G.

    2007-01-01

    The activity of transportation of radioactive materials is in constant evolution; air transport of radio elements for medical use is growing rapidly as well as transport of instruments equipped with radioactive sources for inspections of buildings (controls of presence of lead in paintings) and in industry (non destructive examination of welding by gammagraphy, controls of density on building sites). Transports associated with the recycling of plutonium for the production of electricity by nuclear energy are now accomplished in routine. Globally, 900.000 packages are shipped each year in France; among them, approximately 100.000 packages belong to the category for which design approval is required. To maintain a high level of safety for this activity by limiting the probability of occurrence, the severity and consequences of the incidents and accidents, strict rules are implemented by users under the control of the Safety Authority According to the systematic approach of defence in depth, which is defined by the three principles of safety in design, of operational reliability and of effectiveness of emergency response, the robustness of the design of the package is of primary importance. It is based on regulatory requirements relating to the functions of safety (containment of radioactivity, protection against radiation and prevention of the risks of criticality) that must be ensured by the package in conditions of transport as well as in accident conditions. These rules and the way of applying them evolve with time. Indeed, on the one hand the regulation is reexamined periodically; on the other hand, the technical knowledge on the behaviour of the packages subject to the above mentioned conditions and the means of evaluation of this behaviour progress permanently

  13. Lights All Askew: Systematics in Galaxy Images from Megaparsecs to Microns

    Science.gov (United States)

    Bradshaw, Andrew Kenneth

    The stars and galaxies are not where they seem. In the process of imaging and measurement, the light from distant objects is distorted, blurred, and skewed by several physical effects on scales from megaparsecs to microns. Charge-coupled devices (CCDs) provide sensitive detection of this light, but introduce their own problems in the form of systematic biases. Images of these stars and galaxies are formed in CCDs when incoming light generates photoelectrons which are then collected in a pixel's potential well and measured as signal. However, these signal electrons can be diverted from purely parallel paths toward the pixel wells by transverse fields sourced by structural elements of the CCD, accidental imperfections in fabrication, or dynamic electric fields induced by other collected charges. These charge transport anomalies lead to measurable systematic errors in the images which bias cosmological inferences based on them. The physics of imaging therefore deserves thorough investigation, which is performed in the laboratory using a unique optical beam simulator and in computer simulations of charge transport. On top of detector systematics, there are often biases in the mathematical analysis of pixelized images; in particular, the location, shape, and orientation of stars and galaxies. Using elliptical Gaussians as a toy model for galaxies, it is demonstrated how small biases in the computed image moments lead to observable orientation patterns in modern survey data. Also presented are examples of the reduction of data and fitting of optical aberrations of images in the lab and on the sky which are modeled by physically or mathematically-motivated methods. Finally, end-to-end analysis of the weak gravitational lensing signal is presented using deep sky data as well as in N-body simulations. It is demonstrated how measured weak lens shear can be transformed by signal matched filters which aid in the detection of mass overdensities and separate signal from noise. A

  14. Recommended direct simulation Monte Carlo collision model parameters for modeling ionized air transport processes

    Energy Technology Data Exchange (ETDEWEB)

    Swaminathan-Gopalan, Krishnan; Stephani, Kelly A., E-mail: ksteph@illinois.edu [Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801 (United States)

    2016-02-15

    A systematic approach for calibrating the direct simulation Monte Carlo (DSMC) collision model parameters to achieve consistency in the transport processes is presented. The DSMC collision cross section model parameters are calibrated for high temperature atmospheric conditions by matching the collision integrals from DSMC against ab initio based collision integrals that are currently employed in the Langley Aerothermodynamic Upwind Relaxation Algorithm (LAURA) and Data Parallel Line Relaxation (DPLR) high temperature computational fluid dynamics solvers. The DSMC parameter values are computed for the widely used Variable Hard Sphere (VHS) and the Variable Soft Sphere (VSS) models using the collision-specific pairing approach. The recommended best-fit VHS/VSS parameter values are provided over a temperature range of 1000-20 000 K for a thirteen-species ionized air mixture. Use of the VSS model is necessary to achieve consistency in transport processes of ionized gases. The agreement of the VSS model transport properties with the transport properties as determined by the ab initio collision integral fits was found to be within 6% in the entire temperature range, regardless of the composition of the mixture. The recommended model parameter values can be readily applied to any gas mixture involving binary collisional interactions between the chemical species presented for the specified temperature range.

  15. The transportation institutional plan: Cooperative planning for NWPA transportation

    International Nuclear Information System (INIS)

    Denny, S.H.; Livingston-Behan, E.A.

    1987-01-01

    The Transportation Institutional Plan, published in 1986 by the U.S. Department of Energy's Office of Civilian Radioactive Waste Management (OCRWM), defines a process for effective interaction among those who may be affected by transportation activities conducted under provisions of the Nuclear Waste Policy Act of 1982 (NWPA). The Plan describes formal mechanisms for identifying, addressing, and resolving specific transportation issues. An appendix to the Plan includes detailed discussion of the following transportation issues: (1) the transportation of defense waste; (2) prenotification; (3) physical and rail shipments; (4) highway routing; (5) rail routing; (6) inspection and enforcement for highway and rail shipments; (7) emergency response; (8) liability coverage for transportation to NWPA facilities; (9) cask design and testing; (10) overweight truck shipments; (11) rail service analysis; (12) mixture of transportation modes; (13) transportation infrastructure improvements; (14) OCRWM training standards; (15) transportation operational procedures; and (16) State, Tribal, and local regulation of transportation. The OCRWM's intent is to provide an open accounting of planning, to identify opportunities for public involvement in program activities, and to foster communication and negotiation in the cooperative development of a safe, efficient, and cost-effective NWPA transportation program

  16. A Process-Based Transport-Distance Model of Aeolian Transport

    Science.gov (United States)

    Naylor, A. K.; Okin, G.; Wainwright, J.; Parsons, A. J.

    2017-12-01

    We present a new approach to modeling aeolian transport based on transport distance. Particle fluxes are based on statistical probabilities of particle detachment and distributions of transport lengths, which are functions of particle size classes. A computational saltation model is used to simulate transport distances over a variety of sizes. These are fit to an exponential distribution, which has the advantages of computational economy, concordance with current field measurements, and a meaningful relationship to theoretical assumptions about mean and median particle transport distance. This novel approach includes particle-particle interactions, which are important for sustaining aeolian transport and dust emission. Results from this model are compared with results from both bulk- and particle-sized-specific transport equations as well as empirical wind tunnel studies. The transport-distance approach has been successfully used for hydraulic processes, and extending this methodology from hydraulic to aeolian transport opens up the possibility of modeling joint transport by wind and water using consistent physics. Particularly in nutrient-limited environments, modeling the joint action of aeolian and hydraulic transport is essential for understanding the spatial distribution of biomass across landscapes and how it responds to climatic variability and change.

  17. The transport forecast - an important stage of transport management

    Science.gov (United States)

    Dragu, Vasile; Dinu, Oana; Oprea, Cristina; Alina Roman, Eugenia

    2017-10-01

    The transport system is a powerful system with varying loads in operation coming from changes in freight and passenger traffic in different time periods. The variations are due to the specific conditions of organization and development of socio-economic activities. The causes of varying loads can be included in three groups: economic, technical and organizational. The assessing of transport demand variability leads to proper forecast and development of the transport system, knowing that the market price is determined on equilibrium between supply and demand. The reduction of transport demand variability through different technical solutions, organizational, administrative, legislative leads to an increase in the efficiency and effectiveness of transport. The paper presents a new way of assessing the future needs of transport through dynamic series. Both researchers and practitioners in transport planning can benefit from the research results. This paper aims to analyze in an original approach how a good transport forecast can lead to a better management in transport, with significant effects on transport demand full meeting in quality terms. The case study shows how dynamic series of statistics can be used to identify the size of future demand addressed to the transport system.

  18. Information management and collection for US DOE's packaging and transportation needs in the '90's

    International Nuclear Information System (INIS)

    Wheeler, T.A.; Luna, R.E.; McClure, J.D.; Quinn, G.

    1992-01-01

    The Transportation Assessment and Integration (TRAIN) Project (US DOE 1992) was established to provide a systematic approach to identify the problems and needs that will affect the capability of the United States Department of Energy (US DOE) to provide itself with cost-effective, efficient, and coordinated transportation services during the 1990s. Eight issue areas were identified to be included in the TRAIN Project, with one principal investigator assigned to each. The eight areas are as follows: (1) Packaging and Transportation Needs (PATN) in the 1990s; (2) Institutional and Outreach Programs; (3) Regulatory Impacts on Transportation Management; (4) Traffic and Packaging Operations; (5) Research and Development Requirements; (6) Training Support; (7) Emergency Preparedness Requirements; and (8) US DOE-EM 561 Roles and Responsibilities. This paper focuses on the results of the PATN activity of TRAIN. The objective of PATN is to prepare the US DOE, in general, and US DOE-EM 561 (Environmental Restoration and Waste Management (EM), Office of Technology Development, Transportation) in particular, to respond to the transportation needs of program elements in the Department. One of the first tasks in evaluating these needs was to formulate the potential for transportation of radioactive materials in the next decade. The US DOE is responsible for a relatively small fraction of the national shipments of radioactive material. Nevertheless, the assessment of its packaging and transportation needs presents a problem of wide scope. Large quantities of material are shipped each year throughout the US DOE establishment as a result of its work in the various field offices, national laboratories, and contractor facilities which carry out its programs

  19. Systematics in the electron transport and magnetic properties of LnBO3 perovskites

    International Nuclear Information System (INIS)

    Ganguly, P.; Rao, C.N.R.

    1980-01-01

    Systematics in the electrical and magnetic properties of transition metal perovskites LnBO 3 (Ln = rare-earth ion, B = 3d transition metal) with the variation of Ln and B ions are reviewed. The electrical resistivity and activation energy of LnBO 3 compounds increase with the decreasing size of the Ln 3+ ion for a given B ion. The low-spin to high-spin transition temperature of Co 3+ ion in LnCoO 3 similarly increase with the decrease in size of Ln 3+ while the magnetic ordering temperatures in LnVO 3 , LnFeO 3 , LnCrO 3 and LnSrCo 2 O 6 decrease with decreasing size of the rare-earth ion. These results may be understood in terms of the increasing acidity of the rare earth ion with decreasing size and the competition between the Ln 3+ and the B 3+ ions for covalency with the oxygen ions. The effect of this competition on the metal oxygen covalency and crystal field parameter is discussed in relation to the results obtained and Goodenough's phase diagram. The possibility of d-f exchange interaction in Lasub(1-x)Lnsub(x)NiOsub(3) is also discussed in the light of ESR results. (auth.)

  20. Travel and transport

    DEFF Research Database (Denmark)

    Bill, Jan; Roesdahl, Else

    2007-01-01

    On the interrelationship between travel, transport and society; on land transport, sea and river transport, and on winter transport;  on the related technologies and their developments......On the interrelationship between travel, transport and society; on land transport, sea and river transport, and on winter transport;  on the related technologies and their developments...

  1. How to write a systematic review.

    Science.gov (United States)

    Harris, Joshua D; Quatman, Carmen E; Manring, M M; Siston, Robert A; Flanigan, David C

    2014-11-01

    The role of evidence-based medicine in sports medicine and orthopaedic surgery is rapidly growing. Systematic reviews and meta-analyses are also proliferating in the medical literature. To provide the outline necessary for a practitioner to properly understand and/or conduct a systematic review for publication in a sports medicine journal. Review. The steps of a successful systematic review include the following: identification of an unanswered answerable question; explicit definitions of the investigation's participant(s), intervention(s), comparison(s), and outcome(s); utilization of PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines and PROSPERO registration; thorough systematic data extraction; and appropriate grading of the evidence and strength of the recommendations. An outline to understand and conduct a systematic review is provided, and the difference between meta-analyses and systematic reviews is described. The steps necessary to perform a systematic review are fully explained, including the study purpose, search methodology, data extraction, reporting of results, identification of bias, and reporting of the study's main findings. Systematic reviews or meta-analyses critically appraise and formally synthesize the best existing evidence to provide a statement of conclusion that answers specific clinical questions. Readers and reviewers, however, must recognize that the quality and strength of recommendations in a review are only as strong as the quality of studies that it analyzes. Thus, great care must be used in the interpretation of bias and extrapolation of the review's findings to translation to clinical practice. Without advanced education on the topic, the reader may follow the steps discussed herein to perform a systematic review. © 2013 The Author(s).

  2. Sustainable Transportation

    DEFF Research Database (Denmark)

    Hall, Ralph P.; Gudmundsson, Henrik; Marsden, Greg

    2014-01-01

    The transportation system is the backbone of economic and social progress and the means by which humans access goods and services and connect with one another. Yet, as the scale of transportation activities has grown worldwide, so too have the negative environmental, social, and economic impacts...... that relate to the construction and maintenance of transportation infrastructure and the operation or use of the different transportation modes. The concept of sustainable transportation emerged in response to these concerns as part of the broader notion of sustainable development. Given the transportation...... sector’s significant contribution to global challenges such as climate change, it is often said that sustainable development cannot be achieved without sustainable transportation....

  3. Transport phenomena

    International Nuclear Information System (INIS)

    Kirczenow, G.; Marro, J.

    1974-01-01

    Some simple remarks on the basis of transport theory. - Entropy, dynamics and scattering theory. - Response, relaxation and fluctuation. - Fluctuating hydrodynamics and renormalization of susceptibilities and transport coefficients. - Irreversibility of the transport equations. - Ergodic theory and statistical mechanics. - Correlation functions in Heisenberg magnets. - On the Enskog hard-sphere kinetic eqquation and the transport phenomena of dense simple gases. - What can one learn from Lorentz models. - Conductivity in a magnetic field. - Transport properties in gases in presence of external fields. - Transport properties of dilute gases with internal structure. (orig.) [de

  4. Diverse anisotropy of phonon transport in two-dimensional group IV-VI compounds: A comparative study

    Science.gov (United States)

    Qin, Guangzhao; Qin, Zhenzhen; Fang, Wu-Zhang; Zhang, Li-Chuan; Yue, Sheng-Ying; Yan, Qing-Bo; Hu, Ming; Su, Gang

    2016-05-01

    New classes of two-dimensional (2D) materials beyond graphene, including layered and non-layered, and their heterostructures, are currently attracting increasing interest due to their promising applications in nanoelectronics, optoelectronics and clean energy, where thermal transport is a fundamental physical parameter. In this paper, we systematically investigated the phonon transport properties of the 2D orthorhombic group IV-VI compounds of GeS, GeSe, SnS and SnSe by solving the Boltzmann transport equation (BTE) based on first-principles calculations. Despite their similar puckered (hinge-like) structure along the armchair direction as phosphorene, the four monolayer compounds possess diverse anisotropic properties in many aspects, such as phonon group velocity, Young's modulus and lattice thermal conductivity (κ), etc. Especially, the κ along the zigzag and armchair directions of monolayer GeS shows the strongest anisotropy while monolayer SnS and SnSe show almost isotropy in phonon transport. The origin of the diverse anisotropy is fully studied and the underlying mechanism is discussed in details. With limited size, the κ could be effectively lowered, and the anisotropy could be effectively modulated by nanostructuring, which would extend the applications to nanoscale thermoelectrics and thermal management. Our study offers fundamental understanding of the anisotropic phonon transport properties of 2D materials, and would be of significance for further study, modulation and applications in emerging technologies.

  5. The Importance of Systematics

    Indian Academy of Sciences (India)

    1999-02-18

    Feb 18, 1999 ... Similarly, the work of Nathan Charles Rothschild, a taxonomic authority on flea species, was responsible for the discovery ... The use of genetic data for taxonomic purposes also brings systematics closer to realizing Darwin's desire that classification should reflect evolutionary relationships. Systematics is.

  6. Improving the uptake of systematic reviews: a systematic review of intervention effectiveness and relevance.

    LENUS (Irish Health Repository)

    Wallace, John

    2014-01-01

    Little is known about the barriers, facilitators and interventions that impact on systematic review uptake. The objective of this study was to identify how uptake of systematic reviews can be improved.

  7. Blood Sample Transportation by Pneumatic Transportation Systems

    DEFF Research Database (Denmark)

    Nybo, Mads; Lund, Merete E; Titlestad, Kjell

    2018-01-01

    BACKGROUND: Pneumatic transportation systems (PTSs) are increasingly used for transportation of blood samples to the core laboratory. Many studies have investigated the impact of these systems on different types of analyses, but to elucidate whether PTSs in general are safe for transportation...... analysis, and the hemolysis index). CONCLUSIONS: Owing to their high degree of heterogeneity, the retrieved studies were unable to supply evidence for the safety of using PTSs for blood sample transportation. In consequence, laboratories need to measure and document the actual acceleration forces...

  8. Monte Carlo Transport for Electron Thermal Transport

    Science.gov (United States)

    Chenhall, Jeffrey; Cao, Duc; Moses, Gregory

    2015-11-01

    The iSNB (implicit Schurtz Nicolai Busquet multigroup electron thermal transport method of Cao et al. is adapted into a Monte Carlo transport method in order to better model the effects of non-local behavior. The end goal is a hybrid transport-diffusion method that combines Monte Carlo Transport with a discrete diffusion Monte Carlo (DDMC). The hybrid method will combine the efficiency of a diffusion method in short mean free path regions with the accuracy of a transport method in long mean free path regions. The Monte Carlo nature of the approach allows the algorithm to be massively parallelized. Work to date on the method will be presented. This work was supported by Sandia National Laboratory - Albuquerque and the University of Rochester Laboratory for Laser Energetics.

  9. Impact of vacancy ordering on thermal transport in crystalline phase-change materials

    International Nuclear Information System (INIS)

    Siegert, K S; Lange, F R L; Sittner, E R; Volker, H; Schlockermann, C; Wuttig, M; Siegrist, T

    2015-01-01

    Controlling thermal transport in solids is of paramount importance for many applications. Often thermal management is crucial for a device's performance, as it affects both reliability and power consumption. A number of intricate concepts have been developed to address this challenge, such as diamond-like coatings to enhance the thermal conductivity or low symmetry complex super-structures to reduce it. Here, a different approach is pursued, where we explore the potential of solids with a high yet controllable degree of disorder. Recently, it has been demonstrated that an unconventionally high degree of structural disorder characterizes a number of crystalline phase-change materials (PCMs). This disorder strongly impacts electronic transport and even leads to disorder induced localization (Anderson localization). This raises the question how thermal transport is affected by such conditions. Here thermal transport in highly disordered crystalline Ge–Sb–Te (GST) based PCMs is investigated. Glass-like thermal properties are observed for several crystalline PCMs, which are attributed to strong scattering by disordered point defects. A systematic study of different compounds along the pseudo-binary line between GeTe and Sb 2 Te 3 reveals that disordered vacancies act as point defects responsible for pronounced phonon scattering. Annealing causes a gradual ordering of the vacancies and leads to a more ‘crystal-like’ thermal conductivity. While both vibrational and electronic degrees of freedom are affected by disorder, the consequences differ for different stoichiometries. This opens up a pathway to tune electrical and thermal transport by controlling the degree of disorder. Materials with tailored transport properties may not only help to improve power efficiency and scaling in upcoming phase-change memories but are also of fundamental interest in the field of thermoelectric materials. (key issues review)

  10. Impact of vacancy ordering on thermal transport in crystalline phase-change materials.

    Science.gov (United States)

    Siegert, K S; Lange, F R L; Sittner, E R; Volker, H; Schlockermann, C; Siegrist, T; Wuttig, M

    2015-01-01

    Controlling thermal transport in solids is of paramount importance for many applications. Often thermal management is crucial for a device's performance, as it affects both reliability and power consumption. A number of intricate concepts have been developed to address this challenge, such as diamond-like coatings to enhance the thermal conductivity or low symmetry complex super-structures to reduce it. Here, a different approach is pursued, where we explore the potential of solids with a high yet controllable degree of disorder. Recently, it has been demonstrated that an unconventionally high degree of structural disorder characterizes a number of crystalline phase-change materials (PCMs). This disorder strongly impacts electronic transport and even leads to disorder induced localization (Anderson localization). This raises the question how thermal transport is affected by such conditions. Here thermal transport in highly disordered crystalline Ge-Sb-Te (GST) based PCMs is investigated. Glass-like thermal properties are observed for several crystalline PCMs, which are attributed to strong scattering by disordered point defects. A systematic study of different compounds along the pseudo-binary line between GeTe and Sb2Te3 reveals that disordered vacancies act as point defects responsible for pronounced phonon scattering. Annealing causes a gradual ordering of the vacancies and leads to a more 'crystal-like' thermal conductivity. While both vibrational and electronic degrees of freedom are affected by disorder, the consequences differ for different stoichiometries. This opens up a pathway to tune electrical and thermal transport by controlling the degree of disorder. Materials with tailored transport properties may not only help to improve power efficiency and scaling in upcoming phase-change memories but are also of fundamental interest in the field of thermoelectric materials.

  11. Methodology in conducting a systematic review of systematic reviews of healthcare interventions

    LENUS (Irish Health Repository)

    Smith, Valerie

    2011-02-03

    Abstract Background Hundreds of studies of maternity care interventions have been published, too many for most people involved in providing maternity care to identify and consider when making decisions. It became apparent that systematic reviews of individual studies were required to appraise, summarise and bring together existing studies in a single place. However, decision makers are increasingly faced by a plethora of such reviews and these are likely to be of variable quality and scope, with more than one review of important topics. Systematic reviews (or overviews) of reviews are a logical and appropriate next step, allowing the findings of separate reviews to be compared and contrasted, providing clinical decision makers with the evidence they need. Methods The methods used to identify and appraise published and unpublished reviews systematically, drawing on our experiences and good practice in the conduct and reporting of systematic reviews are described. The process of identifying and appraising all published reviews allows researchers to describe the quality of this evidence base, summarise and compare the review\\'s conclusions and discuss the strength of these conclusions. Results Methodological challenges and possible solutions are described within the context of (i) sources, (ii) study selection, (iii) quality assessment (i.e. the extent of searching undertaken for the reviews, description of study selection and inclusion criteria, comparability of included studies, assessment of publication bias and assessment of heterogeneity), (iv) presentation of results, and (v) implications for practice and research. Conclusion Conducting a systematic review of reviews highlights the usefulness of bringing together a summary of reviews in one place, where there is more than one review on an important topic. The methods described here should help clinicians to review and appraise published reviews systematically, and aid evidence-based clinical decision-making.

  12. Transport and Retention of TiO2 Rutile Nanoparticles in Saturated Porous Media: Influence of Solution pH, Ionic Strength, and the Presence of Humic Acid

    Science.gov (United States)

    The influence of solution pH, ionic strength, and varying concentrations of the Suwannee River Humic Acid (SRHA) on the transport of titanium dioxide (TiO2, rutile) nanoparticle aggregates (nTiO2) in saturated porous media was investigated through systematically examining the tra...

  13. 78 FR 57162 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

    Science.gov (United States)

    2013-09-17

    ... that must be capable of verification by qualified auditors. Besides determining program reimbursement...). Insurers, underwriters, third party administrators, and self-insured/self-administered employers use the...

  14. Establishment and utilization of radiological protection programs for the transport of radioactive material; Establecimiento y utilizacion de programas de proteccion radiologica para el transporte de material radiactivo

    Energy Technology Data Exchange (ETDEWEB)

    Lopez V, J.; Capadona, N. [Autoridad Regulatoria Nuclear, Av. Del Libertador 8250 (1429) Buenos Aires, (Argentina)]. e-mail: jlvietri@sede.arn.gov.ar

    2006-07-01

    The present work has by objective to indicate rules for the establishment and the use of the Radiological Protection Programs (PPR) that are of application to the transport of radioactive materials according to that required by the Transport Regulation of the International Atomic Energy Agency (IAEA). The PPR are established and applied in systematic form for remittent, transport and addressees, to consider the measures of radiological protection and its appropriately control during the transport stages of radioactive material. In particular, in the work it is analyzed the PPR applied to the operative stage, in the one that can be considered as one of the more important documents to use since it summarizes the evaluations and the necessary controls of radiological protection. Also it is analyzed the importance that this document gets ready on the base that it converges in the the analyses, evaluations and data that have been kept in mind during the previous stages of design of bundles and production of packings, the types and quantities of involved bundles, as well as of considering the quantities of expeditions and its frequencies, the ways of transport, etc. It is included a brief description of the parts that the PPR conforms on the base of that suggested in the advanced draft of the TS-G-1.5 Guide 'Radiation Protection Programmes for Transport of Radioactive Material', of October, 2005, of the IAEA: objectives. necessity, scope, basic elements of a PPR in function of the occupational dose. assignment of functions and responsibilities for the establishment of a PPR, evaluation and dose optimization, surface contamination, segregation and other protection measures, responses in emergencies. training and administration systems for baled and transport of radioactive material. Next an example of PPR for the transport of bundles of the A Type by lorry with content of radiopharmaceuticals that are the bundles more used worldwide in the expeditions of

  15. A computationally efficient moment-preserving Monte Carlo electron transport method with implementation in Geant4

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, D.A., E-mail: ddixon@lanl.gov [Los Alamos National Laboratory, P.O. Box 1663, MS P365, Los Alamos, NM 87545 (United States); Prinja, A.K., E-mail: prinja@unm.edu [Department of Nuclear Engineering, MSC01 1120, 1 University of New Mexico, Albuquerque, NM 87131-0001 (United States); Franke, B.C., E-mail: bcfrank@sandia.gov [Sandia National Laboratories, Albuquerque, NM 87123 (United States)

    2015-09-15

    This paper presents the theoretical development and numerical demonstration of a moment-preserving Monte Carlo electron transport method. Foremost, a full implementation of the moment-preserving (MP) method within the Geant4 particle simulation toolkit is demonstrated. Beyond implementation details, it is shown that the MP method is a viable alternative to the condensed history (CH) method for inclusion in current and future generation transport codes through demonstration of the key features of the method including: systematically controllable accuracy, computational efficiency, mathematical robustness, and versatility. A wide variety of results common to electron transport are presented illustrating the key features of the MP method. In particular, it is possible to achieve accuracy that is statistically indistinguishable from analog Monte Carlo, while remaining up to three orders of magnitude more efficient than analog Monte Carlo simulations. Finally, it is shown that the MP method can be generalized to any applicable analog scattering DCS model by extending previous work on the MP method beyond analytical DCSs to the partial-wave (PW) elastic tabulated DCS data.

  16. 77 FR 41107 - Enterprise Underwriting Standards

    Science.gov (United States)

    2012-07-12

    [email protected] . Please include ``RIN 2590- AA53'' in the subject line of the message. U.S. Mail, United Parcel Service, Federal Express, or Other Mail Service: The mailing address for comments is: Alfred M...

  17. 77 FR 36085 - Enterprise Underwriting Standards

    Science.gov (United States)

    2012-06-15

    ... of Environmental Entrepreneurs asserted that ``PACE can further reduce risk to existing lenders by... energy efficient product purchases, a dramatic reduction in energy prices likely would make it easier for...

  18. Thermal transport in oblique finned microminichannels

    CERN Document Server

    Fan, Yan; Singh, Pawan Kumar; Lee, Yong Jiun

    2015-01-01

    The main aim of this book is to introduce and give an overview of a novel, easy, and highly effective heat transfer augmentation technique for single-phase micro/minichannel heat sink. The specific objectives of the volume are to: Introduce a novel planar oblique fin microchannel and cylindrical oblique fin minichannel heat sink design using passive heat transfer enhancement techniques  Investigate the thermal transport in both planar and cylindrical oblique fin structures through numerical simulation and systematic experimental studies. Evaluate the feasibility of employing the proposed solution in cooling non-uniform heat fluxes and hotspot suppression Conduct the similarity analysis and parametric study to obtain empirical correlations to evaluate the total heat transfer rate of the oblique fin heat sink Investigate the flow mechanism and optimize the dimensions of cylindrical oblique fin heat sink Investigate the influence of edge effect on flow and temperature uniformity in these oblique fin chan...

  19. Building waste management core indicators through Spatial Material Flow Analysis: Net recovery and transport intensity indexes

    Energy Technology Data Exchange (ETDEWEB)

    Font Vivanco, David, E-mail: font@cml.leidenuniv.nl [Institut de Ciencia i Tecnologia Ambientals (ICTA), Departament d' Enginyeria Quimica, Universitat Autonoma de Barcelona (UAB), 08193 Bellaterra, Barcelona (Spain); Institute of Environmental Sciences (CML), Leiden University, P.O. Box 9518, 2300 RA Leiden (Netherlands); Puig Ventosa, Ignasi [ENT Environment and Management, Carrer Sant Joan 39, First Floor, 08800 Vilanova i la Geltru, Barcelona (Spain); Gabarrell Durany, Xavier [Institut de Ciencia i Tecnologia Ambientals (ICTA), Departament d' Enginyeria Quimica, Universitat Autonoma de Barcelona (UAB), 08193 Bellaterra, Barcelona (Spain)

    2012-12-15

    Highlights: Black-Right-Pointing-Pointer Sustainability and proximity principles have a key role in waste management. Black-Right-Pointing-Pointer Core indicators are needed in order to quantify and evaluate them. Black-Right-Pointing-Pointer A systematic, step-by-step approach is developed in this study for their development. Black-Right-Pointing-Pointer Transport may play a significant role in terms of environmental and economic costs. Black-Right-Pointing-Pointer Policy action is required in order to advance in the consecution of these principles. - Abstract: In this paper, the material and spatial characterization of the flows within a municipal solid waste (MSW) management system are combined through a Network-Based Spatial Material Flow Analysis. Using this information, two core indicators are developed for the bio-waste fraction, the Net Recovery Index (NRI) and the Transport Intensity Index (TII), which are aimed at assessing progress towards policy-related sustainable MSW management strategies and objectives. The NRI approaches the capacity of a MSW management system for converting waste into resources through a systematic metabolic approach, whereas the TII addresses efficiency in terms of the transport requirements to manage a specific waste flow throughout the entire MSW management life cycle. Therefore, both indicators could be useful in assessing key MSW management policy strategies, such as the consecution of higher recycling levels (sustainability principle) or the minimization of transport by locating treatment facilities closer to generation sources (proximity principle). To apply this methodological approach, the bio-waste management system of the region of Catalonia (Spain) has been chosen as a case study. Results show the adequacy of both indicators for identifying those points within the system with higher capacity to compromise its environmental, economic and social performance and therefore establishing clear targets for policy

  20. Boron transport in plants: co-ordinated regulation of transporters

    Science.gov (United States)

    Miwa, Kyoko; Fujiwara, Toru

    2010-01-01

    Background The essentiality of boron (B) for plant growth was established >85 years ago. In the last decade, it has been revealed that one of the physiological roles of B is cross-linking the pectic polysaccharide rhamnogalacturonan II in primary cell walls. Borate cross-linking of pectic networks serves both for physical strength of cell walls and for cell adhesion. On the other hand, high concentrations of B are toxic to plant growth. To avoid deficiency and toxicity problems, it is important for plants to maintain their tissue B concentrations within an optimum range by regulating transport processes. Boron transport was long believed to be a passive, unregulated process, but the identification of B transporters has suggested that plants sense and respond to the B conditions and regulate transporters to maintain B homeostasis. Scope Transporters responsible for efficient B uptake by roots, xylem loading and B distribution among leaves have been described. These transporters are required under B limitation for efficient acquisition and utilization of B. Transporters important for tolerating high B levels in the environment have also been identified, and these transporters export B from roots back to the soil. Two types of transporters are involved in these processes: NIPs (nodulin-26-like intrinsic proteins), boric acid channels, and BORs, B exporters. It is demonstrated that the expression of genes encoding these transporters is finely regulated in response to B availability in the environment to ensure tissue B homeostasis. Furthermore, plants tolerant to stress produced by low B or high B in the environment can be generated through altered expression of these transporters. Conclusions The identification of the first B transporter led to the discovery that B transport was a process mediated not only by passive diffusion but also by transporters whose activity was regulated in response to B conditions. Now it is evident that plants sense internal and external B

  1. Approach for systematic evaluation of transuranic waste management alternatives

    International Nuclear Information System (INIS)

    Hong, K.; Koebnick, B.; Kotek, T.

    1994-01-01

    This paper describes an approach for systematic evaluation of management alternatives that are being considered for the treatment, storage, and disposal of transuranic waste (TRUW) at U.S. Department of Energy sites. The approach, which is currently under development, would apply WASTE-MGMT, a database application model developed at Argonne National Laboratory, to estimate projected environmental releases and would evaluate impact measures such as health risk and costs associated with each of the waste management alternatives. The customized application would combine site-specific TRUW inventory and characterization data with treatment and transportation parameters to estimate the quantities and characteristics of the wastes to be treated, emissions of hazardous substances from the treatment facilities, and the quantities and characteristics of the wastes to be shipped between sites. These data would then be used to estimate for several TRUW management scenarios the costs and health risks of constructing and operating the required treatment facilities and of transporting TRUW for treatment and final disposal. Treatment, storage, and disposal of TRUW at DOE sites is composed of many variables and options at each stage. The approach described in this paper would provide for efficient consideration of all of these facets when evaluating potentially feasible TRUW management alternatives. By expanding existing databases, this model could eventually be adapted to accommodate the introduction of new treatment technologies, updated TRUW characterization data, and/or revised waste acceptance criteria

  2. Cost-effectiveness of lung cancer screening and treatment methods: a systematic review of systematic reviews.

    Science.gov (United States)

    Azar, Farbod Ebadifard; Azami-Aghdash, Saber; Pournaghi-Azar, Fatemeh; Mazdaki, Alireza; Rezapour, Aziz; Ebrahimi, Parvin; Yousefzadeh, Negar

    2017-06-19

    Due to extensive literature in the field of lung cancer and their heterogeneous results, the aim of this study was to systematically review of systematic reviews studies which reviewed the cost-effectiveness of various lung cancer screening and treatment methods. In this systematic review of systematic reviews study, required data were collected searching the following key words which selected from Mesh: "lung cancer", "lung oncology", "lung Carcinoma", "lung neoplasm", "lung tumors", "cost- effectiveness", "systematic review" and "Meta-analysis". The following databases were searched: PubMed, Cochrane Library electronic databases, Google Scholar, and Scopus. Two reviewers (RA and A-AS) evaluated the articles according to the checklist of "assessment of multiple systematic reviews" (AMSTAR) tool. Overall, information of 110 papers was discussed in eight systematic reviews. Authors focused on cost-effectiveness of lung cancer treatments in five systematic reviews. Targeted therapy options (bevacizumab, Erlotinib and Crizotinib) show an acceptable cost-effectiveness. Results of three studies failed to show cost-effectiveness of screening methods. None of the studies had used the meta-analysis method. The Quality of Health Economic Studies (QHES) tool and Drummond checklist were mostly used in assessing the quality of articles. Most perspective was related to the Payer (64 times) and the lowest was related to Social (11times). Most cases referred to Incremental analysis (82%) and also the lowest point of referral was related to Discounting (in 49% of the cases). The average quality score of included studies was calculated 9.2% from 11. Targeted therapy can be an option for the treatment of lung cancer. Evaluation of the cost-effectiveness of computerized tomographic colonography (CTC) in lung cancer screening is recommended. The perspective of the community should be more taken into consideration in studies of cost-effectiveness. Paying more attention to the topic of

  3. Transport relaxation measurements and glassy state effects in superconducting MgB2

    International Nuclear Information System (INIS)

    Olutas, M.; Yetis, H.; Altinkok, A.; Kilic, A.; Kilic, K.

    2008-01-01

    Time dependent effects in superconducting MgB 2 have been studied systematically for the first time by transport relaxation measurements (V-t curves) as a function of transport current (I), temperature (T) and external magnetic field (H). At very low dissipation levels (below ∼1 μV), it was observed that the sample voltage grows up smoothly in time by exhibiting the details of initial stage of relaxation process. At high dissipation levels, steady state corresponding to constant flow rate is maintained within a very short time and monitoring of details of flux dynamic evolving along sample becomes difficult on long time scales. Another interesting behavior is the appearance of voltage peak when the transport current was reduced to a finite value. After peak, it was observed that the sample voltage relaxes smoothly by leveling off within a very short time. The evolution of V-t curves suggests that formation of resistive flow channels along sample develops easily, which is quite similar to that of obtained for the superconducting ceramic samples whose grain boundaries are improved. Time dependent effects were also observed in magnetovoltage measurements (V-H curves) as the field sweep rate (dH/dt) varies. The observations were interpreted mainly in terms of flux trapping in grains

  4. Transport of Escherichia coli phage through saturated porous media considering managed aquifer recharge.

    Science.gov (United States)

    Zhang, Wenjing; Li, Shuo; Wang, Shuang; Lei, Liancheng; Yu, Xipeng; Ma, Tianyi

    2018-03-01

    Virus is one of the most potentially harmful microorganisms in groundwater. In this paper, the effects of hydrodynamic and hydrogeochemical conditions on the transportation of the colloidal virus considering managed aquifer recharge were systematically investigated. Escherichia coli phage, vB_EcoM-ep3, has a broad host range and was able to lyse pathogenic Escherichia coli. Bacteriophage with low risk to infect human has been found extensively in the groundwater environment, so it is considered as a representative model of groundwater viruses. Laboratory studies were carried out to analyze the transport of the Escherichia coli phage under varying conditions of pH, ionic strength, cation valence, flow rate, porous media, and phosphate buffer concentration. The results indicated that decreasing the pH will increase the adsorption of Escherichia coli phage. Increasing the ionic strength, either Na + or Ca 2+ , will form negative condition for the migration of Escherichia coli phage. A comparison of different cation valence tests indicated that changes in transport and deposition were more pronounced with divalent Ca 2+ than monovalent Na + . As the flow rate increases, the release of Escherichia coli phage increases and the retention of Escherichia coli phage in the aquifer medium reduces. Changes in porous media had a significant effect on Escherichia coli phage migration. With increase of phosphate buffer concentration, the suspension stability and migration ability of Escherichia coli phage are both increased. Based on laboratory-scale column experiments, a one-dimensional transport model was established to quantitatively describe the virus transport in saturated porous medium.

  5. The effects of sodium-glucose co-transporter 2 inhibitors in patients with type 2 diabetes

    DEFF Research Database (Denmark)

    Storgaard, Heidi; Gluud, Lise Lotte; Christensen, Mikkel

    2014-01-01

    INTRODUCTION: Sodium-glucose co-transporter 2 inhibitors (SGLT-2i) increase urinary glucose excretion through a reduced renal glucose reabsorption. We plan to perform a systematic review of SGLT-2i for treatment of type 2 diabetes. METHODS AND ANALYSIS: A systematic review with meta......-analyses of randomised clinical trials on SGLT-2i versus placebo, other oral glucose lowering drugs or insulin for patients with type 2 diabetes will be performed. The primary end point will be the glycated haemoglobin. Secondary end points will include changes in body weight, body mass index, fasting plasma glucose...... to the knowledge regarding the beneficial and harmful effects of SGLT-2i in patients with type 2 diabetes. We plan to publish the study irrespective of the results. RESULTS: The study will be disseminated by peer-review publication and conference presentation. TRIAL REGISTRATION NUMBER: PROSPERO CRD42014008960...

  6. Study of the charge transport characteristics of dendrimer molecular thin films

    Energy Technology Data Exchange (ETDEWEB)

    Li, J.C., E-mail: jcli@mail.neu.edu.cn; Han, N.; Wang, S.S.; Ba, D.C.

    2011-05-31

    In this work, we systematically studied the electrical characteristics of two types of dendritic arylamine thin film devices. We observed that, for devices with different interfacial structures, their charge injection barriers and transport properties are obviously different. The smallest charge injection barrier is observed in dendrimer devices without charge-transfer interfacial layers. The Richardson-Schottky thermionic emission model can be well used to fit the experimental current-voltage characteristics at a lower voltage region. The charge injection barrier increases about 0.4 eV and 0.5 eV when a 1-decanethiol self-assembly layer and -CN terminated dendrimer thin films are inserted as the interfacial layer, respectively. It is shown that the molecule/electrode charge-transfer interfaces can largely affect the device charge injection/transport process and consequently change the device performance. In this case, the space charge limited conduction theory is more applicable to simulate the device conduction mechanism. Owing to its ultra-thin thickness, the self-assembly monolayer technique is proved to be an efficient approach in engineering the interfacial electronic structures of dendrimer thin film devices.

  7. Study of the charge transport characteristics of dendrimer molecular thin films

    International Nuclear Information System (INIS)

    Li, J.C.; Han, N.; Wang, S.S.; Ba, D.C.

    2011-01-01

    In this work, we systematically studied the electrical characteristics of two types of dendritic arylamine thin film devices. We observed that, for devices with different interfacial structures, their charge injection barriers and transport properties are obviously different. The smallest charge injection barrier is observed in dendrimer devices without charge-transfer interfacial layers. The Richardson-Schottky thermionic emission model can be well used to fit the experimental current-voltage characteristics at a lower voltage region. The charge injection barrier increases about 0.4 eV and 0.5 eV when a 1-decanethiol self-assembly layer and -CN terminated dendrimer thin films are inserted as the interfacial layer, respectively. It is shown that the molecule/electrode charge-transfer interfaces can largely affect the device charge injection/transport process and consequently change the device performance. In this case, the space charge limited conduction theory is more applicable to simulate the device conduction mechanism. Owing to its ultra-thin thickness, the self-assembly monolayer technique is proved to be an efficient approach in engineering the interfacial electronic structures of dendrimer thin film devices.

  8. ANALYISIS OF TRANSPORTATION SYSTEMS AND TRANSPORTATION POLICIES IN TURKEY

    OpenAIRE

    Ali Payıdar AKGÜNGÖR; Abdulmuttalip DEMİREL

    2004-01-01

    Transportation systems have to be considered and analysed as a whole while transportation demand, becoming as a natural outcome of socioeconomic and socio-cultural structure, is being evaluated. It is desired that transportation system, which will be selected for both passenger and freight transport, should be rapid, economic, safe, causing least harm to environment and appropriate for the conditions of a country. However, it is difficult for a transportation system to have all these properti...

  9. Nonlocal transport in the presence of transport barriers

    Science.gov (United States)

    Del-Castillo-Negrete, D.

    2013-10-01

    There is experimental, numerical, and theoretical evidence that transport in plasmas can, under certain circumstances, depart from the standard local, diffusive description. Examples include fast pulse propagation phenomena in perturbative experiments, non-diffusive scaling in L-mode plasmas, and non-Gaussian statistics of fluctuations. From the theoretical perspective, non-diffusive transport descriptions follow from the relaxation of the restrictive assumptions (locality, scale separation, and Gaussian/Markovian statistics) at the foundation of diffusive models. We discuss an alternative class of models able to capture some of the observed non-diffusive transport phenomenology. The models are based on a class of nonlocal, integro-differential operators that provide a unifying framework to describe non- Fickian scale-free transport, and non-Markovian (memory) effects. We study the interplay between nonlocality and internal transport barriers (ITBs) in perturbative transport including cold edge pulses and power modulation. Of particular interest in the nonlocal ``tunnelling'' of perturbations through ITBs. Also, flux-gradient diagrams are discussed as diagnostics to detect nonlocal transport processes in numerical simulations and experiments. Work supported by the US Department of Energy.

  10. The quality of systematic reviews about interventions for refractive error can be improved: a review of systematic reviews.

    Science.gov (United States)

    Mayo-Wilson, Evan; Ng, Sueko Matsumura; Chuck, Roy S; Li, Tianjing

    2017-09-05

    Systematic reviews should inform American Academy of Ophthalmology (AAO) Preferred Practice Pattern® (PPP) guidelines. The quality of systematic reviews related to the forthcoming Preferred Practice Pattern® guideline (PPP) Refractive Errors & Refractive Surgery is unknown. We sought to identify reliable systematic reviews to assist the AAO Refractive Errors & Refractive Surgery PPP. Systematic reviews were eligible if they evaluated the effectiveness or safety of interventions included in the 2012 PPP Refractive Errors & Refractive Surgery. To identify potentially eligible systematic reviews, we searched the Cochrane Eyes and Vision United States Satellite database of systematic reviews. Two authors identified eligible reviews and abstracted information about the characteristics and quality of the reviews independently using the Systematic Review Data Repository. We classified systematic reviews as "reliable" when they (1) defined criteria for the selection of studies, (2) conducted comprehensive literature searches for eligible studies, (3) assessed the methodological quality (risk of bias) of the included studies, (4) used appropriate methods for meta-analyses (which we assessed only when meta-analyses were reported), (5) presented conclusions that were supported by the evidence provided in the review. We identified 124 systematic reviews related to refractive error; 39 met our eligibility criteria, of which we classified 11 to be reliable. Systematic reviews classified as unreliable did not define the criteria for selecting studies (5; 13%), did not assess methodological rigor (10; 26%), did not conduct comprehensive searches (17; 44%), or used inappropriate quantitative methods (3; 8%). The 11 reliable reviews were published between 2002 and 2016. They included 0 to 23 studies (median = 9) and analyzed 0 to 4696 participants (median = 666). Seven reliable reviews (64%) assessed surgical interventions. Most systematic reviews of interventions for

  11. Plant Transporter Identification

    DEFF Research Database (Denmark)

    Larsen, Bo

    Membrane transport proteins (transporters) play a critical role for numerous biological processes, by controlling the movements of ions and molecules in and out of cells. In plants, transporters thus function as gatekeepers between the plant and its surrounding environment and between organs......, tissues, cells and intracellular compartments. Since plants are highly compartmentalized organisms with complex transportation infrastructures, they consequently have many transporters. However, the vast majority of predicted transporters have not yet been experimentally verified to have transport...... activity. This project contains a review of the implemented methods, which have led to plant transporter identification, and present our progress on creating a high-throughput functional genomics transporter identification platform....

  12. 75 FR 53727 - Self-Regulatory Organizations; NASDAQ OMX PHLX, Inc.; Order Approving Proposed Rule Change, as...

    Science.gov (United States)

    2010-09-01

    ... underwritings; (ii) supervision of market making commitments; (iii) final approval of advertisements as these... designed to prevent fraudulent and manipulative acts and practices, to promote just and equitable...

  13. Effect of interfaces on electron transport properties of MoS2-Au Contacts

    Science.gov (United States)

    Aminpour, Maral; Hapala, Prokop; Le, Duy; Jelinek, Pavel; Rahman, Talat S.; Rahman's Group Collaboration; Nanosurf Lab Collaboration

    2014-03-01

    Single layer MoS2 is a promising material for future electronic devices such as transistors since it has good transport characteristics with mobility greater than 200 cm-1V-1s-1 and on-off current ratios up to 108. However, before MoS2 can become a mainstream electronic material for the semiconductor industry, the design of low resistive metal-semiconductor junctions as contacts of the electronic devices needs to be addressed and studied systematically. We have examined the effect of Au contacts on the electronic transport properties of single layer MoS2 using density functional theory in combination with the non-equilibrium Green's function method. The Schottky barrier between Au contact and MoS2, transmission spectra, and I-V curves will be reported and discussed as a function of MoS2 and Au interfaces of varying geometry. This work is supported in part by the US Department of Energy under grant DE-FG02-07ER15842.

  14. Transport coefficients for carbon, hydrogen, and the organic mixture C2H3

    International Nuclear Information System (INIS)

    Rinker, G.

    1986-02-01

    Electrical and thermal transport coefficients are calculated for amorphous elemental carbon and hydrogen, using the best available systematic theoretical methods. The density range considered is 10 -3 g/cm 3 less than or equal to rho less than or equal to 10 6 g/cm 3 for carbon, and 10 -4 g/cm 3 less than or equal to rho less than or equal to 10 5 g/cm 3 for hydrogen. The temperature range considered is 10 -2 eV less than or equal to kT less than or equal to 10 4 eV. Calculational methods include relativistic partial-wave analysis of the extended Ziman theory, and nonrelativistic plane-wave analysis (Born approximation) of the original Ziman theory. Physical models include relativistic Dirac-Fock-Slater and nonrelativistic Thomas-Fermi-Dirac electron-ion potentials, and one-component-plasma ion-ion structure factors. A mixing algorithm is used to obtain approximate transport coefficients for the atomic ratio C 2 H 3 . 10 refs., 31 figs

  15. A vadose zone Transport Processes Investigation within the glacial till at the Fernald Environmental Management Project

    International Nuclear Information System (INIS)

    Schwing, J.; Roepke, Craig Senninger; Brainard, James Robert; Glass, Robert John Jr.; Mann, Michael J.A.; Holt, Robert M..; Kriel, Kelly

    2007-01-01

    This report describes a model Transport Processes Investigation (TPI) where field-scale vadose zone flow and transport processes are identified and verified through a systematic field investigation at a contaminated DOE site. The objective of the TPI is to help with formulating accurate conceptual models and aid in implementing rational and cost effective site specific characterization strategies at contaminated sites with diverse hydrogeologic settings. Central to the TPI are Transport Processes Characterization (TPC) tests that incorporate field surveys and large-scale infiltration experiments. Hypotheses are formulated based on observed pedogenic and hydrogeologic features as well as information provided by literature searches. The field and literature information is then used to optimize the design of one or more infiltration experiments to field test the hypothesis. Findings from the field surveys and infiltration experiments are then synthesized to formulate accurate flow and transport conceptual models. Here we document a TPI implemented in the glacial till vadose zone at the Fernald Environmental Management Project (FEMP) in Fernald, Ohio, a US Department of Energy (DOE) uranium processing site. As a result of this TPI, the flow and transport mechanisms were identified through visualization of dye stain within extensive macro pore and fracture networks which provided the means for the infiltrate to bypass potential aquatards. Such mechanisms are not addressed in current vadose zone modeling and are generally missed by classical characterization methods

  16. Usefulness of systematic review search strategies in finding child health systematic reviews in MEDLINE

    NARCIS (Netherlands)

    Boluyt, Nicole; Tjosvold, Lisa; Lefebvre, Carol; Klassen, Terry P.; Offringa, Martin

    2008-01-01

    OBJECTIVE: To determine the sensitivity and precision of existing search strategies for retrieving child health systematic reviews in MEDLINE using PubMed. DESIGN: Filter (diagnostic) accuracy study. We identified existing search strategies for systematic reviews, combined them with a filter that

  17. Water-transporting proteins

    DEFF Research Database (Denmark)

    Zeuthen, Thomas

    2010-01-01

    . In the K(+)/Cl(-) and the Na(+)/K(+)/2Cl(-) cotransporters, water is entirely cotransported, while water transport in glucose uniporters and Na(+)-coupled transporters of nutrients and neurotransmitters takes place by both osmosis and cotransport. The molecular mechanism behind cotransport of water...... transport. Epithelial water transport is energized by the movements of ions, but how the coupling takes place is uncertain. All epithelia can transport water uphill against an osmotic gradient, which is hard to explain by simple osmosis. Furthermore, genetic removal of aquaporins has not given support...... to osmosis as the exclusive mode of transport. Water cotransport can explain the coupling between ion and water transport, a major fraction of transepithelial water transport and uphill water transport. Aquaporins enhance water transport by utilizing osmotic gradients and cause the osmolarity...

  18. SMART CITY SERVICES DRIVEN BY IOT: A SYSTEMATIC REVIEW

    Directory of Open Access Journals (Sweden)

    Marko Mijac

    2017-09-01

    Full Text Available The central role in development of information society is taken by smart cities and their novel services through the use of modern technology and smart solutions. The key enabler and driver of smart cities is Internet of Things (IoT. In this paper, we have conducted a systematic literature review in order to investigate proposed smart city services driven by IoT. We have formulated the review protocol to define the research question/s, search strategy, selection criteria, study quality assessment, and data extraction strategy. We have defined the following main research question: What are the reported applications of Internet of Things in the development of smart city services? The papers were categorized by the smart city services they proposed or described. We have recognized the following categories: traffic and transport; environment monitoring; accessibility & healthcare; waste management; public lighting; energy management; city infrastructure; and other.

  19. Using text mining for study identification in systematic reviews: a systematic review of current approaches

    OpenAIRE

    O?Mara-Eves, Alison; Thomas, James; McNaught, John; Miwa, Makoto; Ananiadou, Sophia

    2015-01-01

    Background The large and growing number of published studies, and their increasing rate of publication, makes the task of identifying relevant studies in an unbiased way for inclusion in systematic reviews both complex and time consuming. Text mining has been offered as a potential solution: through automating some of the screening process, reviewer time can be saved. The evidence base around the use of text mining for screening has not yet been pulled together systematically; this systematic...

  20. Transporter taxonomy - a comparison of different transport protein classification schemes.

    Science.gov (United States)

    Viereck, Michael; Gaulton, Anna; Digles, Daniela; Ecker, Gerhard F

    2014-06-01

    Currently, there are more than 800 well characterized human membrane transport proteins (including channels and transporters) and there are estimates that about 10% (approx. 2000) of all human genes are related to transport. Membrane transport proteins are of interest as potential drug targets, for drug delivery, and as a cause of side effects and drug–drug interactions. In light of the development of Open PHACTS, which provides an open pharmacological space, we analyzed selected membrane transport protein classification schemes (Transporter Classification Database, ChEMBL, IUPHAR/BPS Guide to Pharmacology, and Gene Ontology) for their ability to serve as a basis for pharmacology driven protein classification. A comparison of these membrane transport protein classification schemes by using a set of clinically relevant transporters as use-case reveals the strengths and weaknesses of the different taxonomy approaches.

  1. A diffusive ink transport model for lipid dip-pen nanolithography.

    Science.gov (United States)

    Urtizberea, A; Hirtz, M

    2015-10-14

    Despite diverse applications, phospholipid membrane stacks generated by dip-pen nanolithography (DPN) still lack a thorough and systematic characterization that elucidates the whole ink transport process from writing to surface spreading, with the aim of better controlling the resulting feature size and resolution. We report a quantitative analysis and modeling of the dependence of lipid DPN features (area, height and volume) on dwell time and relative humidity. The ink flow rate increases with humidity in agreement with meniscus size growth, determining the overall feature size. The observed time dependence indicates the existence of a balance between surface spreading and the ink flow rate that promotes differences in concentration at the meniscus/substrate interface. Feature shape is controlled by the substrate surface energy. The results are analyzed within a modified model for the ink transport of diffusive inks. At any humidity the dependence of the area spread on the dwell time shows two diffusion regimes: at short dwell times growth is controlled by meniscus diffusion while at long dwell times surface diffusion governs the process. The critical point for the switch of regime depends on the humidity.

  2. The Emergence of Systematic Review in Toxicology.

    Science.gov (United States)

    Stephens, Martin L; Betts, Kellyn; Beck, Nancy B; Cogliano, Vincent; Dickersin, Kay; Fitzpatrick, Suzanne; Freeman, James; Gray, George; Hartung, Thomas; McPartland, Jennifer; Rooney, Andrew A; Scherer, Roberta W; Verloo, Didier; Hoffmann, Sebastian

    2016-07-01

    The Evidence-based Toxicology Collaboration hosted a workshop on "The Emergence of Systematic Review and Related Evidence-based Approaches in Toxicology," on November 21, 2014 in Baltimore, Maryland. The workshop featured speakers from agencies and organizations applying systematic review approaches to questions in toxicology, speakers with experience in conducting systematic reviews in medicine and healthcare, and stakeholders in industry, government, academia, and non-governmental organizations. Based on the workshop presentations and discussion, here we address the state of systematic review methods in toxicology, historical antecedents in both medicine and toxicology, challenges to the translation of systematic review from medicine to toxicology, and thoughts on the way forward. We conclude with a recommendation that as various agencies and organizations adapt systematic review methods, they continue to work together to ensure that there is a harmonized process for how the basic elements of systematic review methods are applied in toxicology. © The Author 2016. Published by Oxford University Press on behalf of the Society of Toxicology.

  3. Chemical transport reactions

    CERN Document Server

    Schäfer, Harald

    2013-01-01

    Chemical Transport Reactions focuses on the processes and reactions involved in the transport of solid or liquid substances to form vapor phase reaction products. The publication first offers information on experimental and theoretical principles and the transport of solid substances and its special applications. Discussions focus on calculation of the transport effect of heterogeneous equilibria for a gas motion between equilibrium spaces; transport effect and the thermodynamic quantities of the transport reaction; separation and purification of substances by means of material transport; and

  4. Uncertainty and sensitivity analysis of environmental transport models

    International Nuclear Information System (INIS)

    Margulies, T.S.; Lancaster, L.E.

    1985-01-01

    An uncertainty and sensitivity analysis has been made of the CRAC-2 (Calculations of Reactor Accident Consequences) atmospheric transport and deposition models. Robustness and uncertainty aspects of air and ground deposited material and the relative contribution of input and model parameters were systematically studied. The underlying data structures were investigated using a multiway layout of factors over specified ranges generated via a Latin hypercube sampling scheme. The variables selected in our analysis include: weather bin, dry deposition velocity, rain washout coefficient/rain intensity, duration of release, heat content, sigma-z (vertical) plume dispersion parameter, sigma-y (crosswind) plume dispersion parameter, and mixing height. To determine the contributors to the output variability (versus distance from the site) step-wise regression analyses were performed on transformations of the spatial concentration patterns simulated. 27 references, 2 figures, 3 tables

  5. Charge transport in electrically doped amorphous organic semiconductors.

    Science.gov (United States)

    Yoo, Seung-Jun; Kim, Jang-Joo

    2015-06-01

    This article reviews recent progress on charge generation by doping and its influence on the carrier mobility in organic semiconductors (OSs). The doping induced charge generation efficiency is generally low in OSs which was explained by the integer charge transfer model and the hybrid charge transfer model. The ionized dopants formed by charge transfer between hosts and dopants can act as Coulomb traps for mobile charges, and the presence of Coulomb traps in OSs broadens the density of states (DOS) in doped organic films. The Coulomb traps strongly reduce the carrier hopping rate and thereby change the carrier mobility, which was confirmed by experiments in recent years. In order to fully understand the doping mechanism in OSs, further quantitative and systematic analyses of charge transport characteristics must be accomplished. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Nuclear fuel transport and particularly spent fuel transport

    International Nuclear Information System (INIS)

    Lenail, B.

    1986-01-01

    Nuclear material transport is an essential activity for COGEMA linking the different steps of the fuel cycle transport systems have to be safe and reliable. Spent fuel transport is more particularly examined in this paper because the development of reprocessing plant. Industrial, techmical and economical aspects are reviewed [fr

  7. Effectiveness of Pilates exercise in treating people with chronic low back pain: a systematic review of systematic reviews

    Directory of Open Access Journals (Sweden)

    Wells Cherie

    2013-01-01

    Full Text Available Abstract Background Systematic reviews provide clinical practice recommendations that are based on evaluation of primary evidence. When systematic reviews with the same aims have different conclusions, it is difficult to ascertain which review reported the most credible and robust findings. Methods This study examined five systematic reviews that have investigated the effectiveness of Pilates exercise in people with chronic low back pain. A four-stage process was used to interpret findings of the reviews. This process included comparison of research questions, included primary studies, and the level and quality of evidence of systematic reviews. Two independent reviewers assessed the level of evidence and the methodological quality of systematic reviews, using the National Health and Medical Research Council hierarchy of evidence, and the Revised Assessment of Multiple Systematic Reviews respectively. Any disagreements were resolved by a third researcher. Results A high level of consensus was achieved between the reviewers. Conflicting findings were reported by the five systematic reviews regarding the effectiveness of Pilates in reducing pain and disability in people with chronic low back pain. Authors of the systematic reviews included primary studies that did not match their questions in relation to treatment or population characteristics. A total of ten primary studies were identified across five systematic reviews. Only two of the primary studies were included in all of the reviews due to different inclusion criteria relating to publication date and status, definition of Pilates, and methodological quality. The level of evidence of reviews was low due to the methodological design of the primary studies. The methodological quality of reviews varied. Those which conducted a meta-analysis obtained higher scores. Conclusion There is inconclusive evidence that Pilates is effective in reducing pain and disability in people with chronic low back

  8. Effectiveness of Pilates exercise in treating people with chronic low back pain: a systematic review of systematic reviews

    Science.gov (United States)

    2013-01-01

    Background Systematic reviews provide clinical practice recommendations that are based on evaluation of primary evidence. When systematic reviews with the same aims have different conclusions, it is difficult to ascertain which review reported the most credible and robust findings. Methods This study examined five systematic reviews that have investigated the effectiveness of Pilates exercise in people with chronic low back pain. A four-stage process was used to interpret findings of the reviews. This process included comparison of research questions, included primary studies, and the level and quality of evidence of systematic reviews. Two independent reviewers assessed the level of evidence and the methodological quality of systematic reviews, using the National Health and Medical Research Council hierarchy of evidence, and the Revised Assessment of Multiple Systematic Reviews respectively. Any disagreements were resolved by a third researcher. Results A high level of consensus was achieved between the reviewers. Conflicting findings were reported by the five systematic reviews regarding the effectiveness of Pilates in reducing pain and disability in people with chronic low back pain. Authors of the systematic reviews included primary studies that did not match their questions in relation to treatment or population characteristics. A total of ten primary studies were identified across five systematic reviews. Only two of the primary studies were included in all of the reviews due to different inclusion criteria relating to publication date and status, definition of Pilates, and methodological quality. The level of evidence of reviews was low due to the methodological design of the primary studies. The methodological quality of reviews varied. Those which conducted a meta-analysis obtained higher scores. Conclusion There is inconclusive evidence that Pilates is effective in reducing pain and disability in people with chronic low back pain. This is due to the small

  9. Effectiveness of Pilates exercise in treating people with chronic low back pain: a systematic review of systematic reviews.

    Science.gov (United States)

    Wells, Cherie; Kolt, Gregory S; Marshall, Paul; Hill, Bridget; Bialocerkowski, Andrea

    2013-01-19

    Systematic reviews provide clinical practice recommendations that are based on evaluation of primary evidence. When systematic reviews with the same aims have different conclusions, it is difficult to ascertain which review reported the most credible and robust findings. This study examined five systematic reviews that have investigated the effectiveness of Pilates exercise in people with chronic low back pain. A four-stage process was used to interpret findings of the reviews. This process included comparison of research questions, included primary studies, and the level and quality of evidence of systematic reviews. Two independent reviewers assessed the level of evidence and the methodological quality of systematic reviews, using the National Health and Medical Research Council hierarchy of evidence, and the Revised Assessment of Multiple Systematic Reviews respectively. Any disagreements were resolved by a third researcher. A high level of consensus was achieved between the reviewers. Conflicting findings were reported by the five systematic reviews regarding the effectiveness of Pilates in reducing pain and disability in people with chronic low back pain. Authors of the systematic reviews included primary studies that did not match their questions in relation to treatment or population characteristics. A total of ten primary studies were identified across five systematic reviews. Only two of the primary studies were included in all of the reviews due to different inclusion criteria relating to publication date and status, definition of Pilates, and methodological quality. The level of evidence of reviews was low due to the methodological design of the primary studies. The methodological quality of reviews varied. Those which conducted a meta-analysis obtained higher scores. There is inconclusive evidence that Pilates is effective in reducing pain and disability in people with chronic low back pain. This is due to the small number and poor methodological

  10. What do we know about preventing school violence? A systematic review of systematic reviews.

    Science.gov (United States)

    Lester, Soraya; Lawrence, Cayleigh; Ward, Catherine L

    2017-03-01

    Many children across the world are exposed to school violence, which undermines their right to education and adversely affects their development. Studies of interventions for school violence suggest that it can be prevented. However, this evidence base is challenging to navigate. We completed a systematic review of interventions to reduce four types of school violence: (a) peer violence; (b) corporal punishment; (c) student-on-teacher violence and (d) teacher-on-student violence. Reviewers independently searched databases and journals. Included studies were published between 2005 and 2015; in English; considered school-based interventions for children and measured violence as an outcome. Many systematic reviews were found, thus we completed a systematic review of systematic reviews. Only systematic reviews on interventions for intimate partner violence (IPV) and peer aggression were found. These reviews were generally of moderate quality. Research on both types of violence was largely completed in North America. Only a handful of programmes demonstrate promise in preventing IPV. Cognitive behavioral, social-emotional and peer mentoring/mediation programmes showed promise in reducing the levels of perpetration of peer aggression. Further research needs to determine the long-term effects of interventions, potential moderators and mediators of program effects, program effects across different contexts and key intervention components.

  11. Enhanced flux pinning in MOCVD-YBCO films through Zr additions: systematic feasibility studies

    International Nuclear Information System (INIS)

    Aytug, T; Paranthaman, M; Specht, E D; Zhang, Y; Kim, K; Zuev, Y L; Cantoni, C; Goyal, A; Christen, D K; Maroni, V A; Chen, Y; Selvamanickam, V

    2010-01-01

    Systematic effects of Zr additions on the structural and flux pinning properties of YBa 2 Cu 3 O 7-δ (YBCO) films deposited by metal-organic chemical vapor deposition (MOCVD) have been investigated. Detailed characterization, conducted by coordinated transport, x-ray diffraction, scanning and transmission electron microscopy analyses, and imaging Raman microscopy have revealed trends in the resulting property/performance correlations of these films with respect to varying mole percentages (mol%) of added Zr. For compositions ≤7.5 mol%, Zr additions lead to improved in-field critical current density, as well as extra correlated pinning along the c-axis direction of the YBCO films via the formation of columnar, self-assembled stacks of BaZrO 3 nanodots.

  12. Predictions of the near edge transport shortfall in DIII-D L-mode plasmas using the trapped gyro-Landau-fluid model

    Energy Technology Data Exchange (ETDEWEB)

    Kinsey, J. E. [CompX, P.O. Box 2672, Del Mar, California 92014 (United States); Staebler, G. M.; Candy, J.; Petty, C. C.; Waltz, R. E. [General Atomics, P.O. Box 85608, San Diego, California 92186-5608 (United States); Rhodes, T. L. [Physics Department and PSTI, University of California, Los Angeles, California 90095 (United States)

    2015-01-15

    Previous studies of DIII-D L-mode plasmas have shown that a transport shortfall exists in that our current models of turbulent transport can significantly underestimate the energy transport in the near edge region. In this paper, the Trapped Gyro-Landau-Fluid (TGLF) drift wave transport model is used to simulate the near edge transport in a DIII-D L-mode experiment designed to explore the impact of varying the safety factor on the shortfall. We find that the shortfall systematically increases with increasing safety factor and is more pronounced for the electrons than for the ions. Within the shortfall dataset, a single high current case has been found where no transport shortfall is predicted. Reduced neutral beam injection power has been identified as the key parameter separating this discharge from other discharges exhibiting a shortfall. Further analysis shows that the energy transport in the L-mode near edge region is not stiff according to TGLF. Unlike the H-mode core region, the predicted temperature profiles are relatively more responsive to changes in auxiliary heating power. In testing the fidelity of TGLF for the near edge region, we find that a recalibration of the collision model is warranted. A recalibration improves agreement between TGLF and nonlinear gyrokinetic simulations performed using the GYRO code with electron-ion collisions. The recalibration only slightly impacts the predicted shortfall.

  13. The need for performance governance to reach sustainable transport

    DEFF Research Database (Denmark)

    Gudmundsson, Henrik

    The objective to set transport on a course towards sustainability is a complex and long term aspiration that is likely to meet, and have already met, several market and governance failures. While many market failures can be countered through careful design of appropriate policy instruments......, the governance failures need a ‘second order’ approach; an approach that involves the re-design of processes and institutional frameworks for anticipation, decision making, implementation, and learning; in short a framework for performance governance. According to the policy scientists Bouckaert and Halligan......, ‘Performance governance’ is what they call the most advanced form of public performance management. In simple models a government collects only sporadic information on performance to satisfy internal reporting. In the performance governance model, performance management is systematic, continuous...

  14. Nanoscale thermal transport. II. 2003-2012

    Science.gov (United States)

    Cahill, David G.; Braun, Paul V.; Chen, Gang; Clarke, David R.; Fan, Shanhui; Goodson, Kenneth E.; Keblinski, Pawel; King, William P.; Mahan, Gerald D.; Majumdar, Arun; Maris, Humphrey J.; Phillpot, Simon R.; Pop, Eric; Shi, Li

    2014-03-01

    A diverse spectrum of technology drivers such as improved thermal barriers, higher efficiency thermoelectric energy conversion, phase-change memory, heat-assisted magnetic recording, thermal management of nanoscale electronics, and nanoparticles for thermal medical therapies are motivating studies of the applied physics of thermal transport at the nanoscale. This review emphasizes developments in experiment, theory, and computation in the past ten years and summarizes the present status of the field. Interfaces become increasingly important on small length scales. Research during the past decade has extended studies of interfaces between simple metals and inorganic crystals to interfaces with molecular materials and liquids with systematic control of interface chemistry and physics. At separations on the order of ˜ 1 nm , the science of radiative transport through nanoscale gaps overlaps with thermal conduction by the coupling of electronic and vibrational excitations across weakly bonded or rough interfaces between materials. Major advances in the physics of phonons include first principles calculation of the phonon lifetimes of simple crystals and application of the predicted scattering rates in parameter-free calculations of the thermal conductivity. Progress in the control of thermal transport at the nanoscale is critical to continued advances in the density of information that can be stored in phase change memory devices and new generations of magnetic storage that will use highly localized heat sources to reduce the coercivity of magnetic media. Ultralow thermal conductivity—thermal conductivity below the conventionally predicted minimum thermal conductivity—has been observed in nanolaminates and disordered crystals with strong anisotropy. Advances in metrology by time-domain thermoreflectance have made measurements of the thermal conductivity of a thin layer with micron-scale spatial resolution relatively routine. Scanning thermal microscopy and thermal

  15. 78 FR 36562 - 30-Day Notice of Proposed Information Collection: Home Equity Conversion Mortgage (HECM...

    Science.gov (United States)

    2013-06-18

    ... with hearing or speech impairments may access this number through TTY by calling the toll-free Federal... analysis, underwriting analysis, and collection of mortgage insurance premiums for loans that meet...

  16. Heuristic Optimization Approach to Selecting a Transport Connection in City Public Transport

    Directory of Open Access Journals (Sweden)

    Kul’ka Jozef

    2017-02-01

    Full Text Available The article presents a heuristic optimization approach to select a suitable transport connection in the framework of a city public transport. This methodology was applied on a part of the public transport in Košice, because it is the second largest city in the Slovak Republic and its network of the public transport creates a complex transport system, which consists of three different transport modes, namely from the bus transport, tram transport and trolley-bus transport. This solution focused on examining the individual transport services and their interconnection in relevant interchange points.

  17. Analyzing the Potential for High-speed Rail as Part of the Multimodal Transportation System in the United States' Midwest Corridor

    Directory of Open Access Journals (Sweden)

    Jeffrey C. Peters

    2014-06-01

    Full Text Available With increasing demand and rising fuel costs, both travel time and cost of current intercity passenger transportation modes are becoming increasingly relevant. Around the world, highspeed rail (HSR is seen as a way to alleviate demand on highways and at airports. Ridership is the critical element in determining the viability of a large capital, long-term transportation investment. This paper provides a systematic, consistent methodology for analyzing systemwide modal ridership with and without a proposed HSR network and analyzes the potential for highspeed rail as part of the existing multimodal transportation system in a region in terms of ridership. Considerations of capital investment (e.g., network design and HSR speed, along with exogenous demographic, technological, economic, and policy trends in the long-term, are used to project ridership over time. This study represents an important step toward a consistent, comprehensive economic analysis of HSR in the United States.

  18. Diffusive charge transport in graphene on SiO 2

    Science.gov (United States)

    Chen, J.-H.; Jang, C.; Ishigami, M.; Xiao, S.; Cullen, W. G.; Williams, E. D.; Fuhrer, M. S.

    2009-07-01

    We review our recent work on the physical mechanisms limiting the mobility of graphene on SiO 2. We have used intentional addition of charged scattering impurities and systematic variation of the dielectric environment to differentiate the effects of charged impurities and short-range scatterers. The results show that charged impurities indeed lead to a conductivity linear in density ( σ(n)∝n) in graphene, with a scattering magnitude that agrees quantitatively with theoretical estimates; increased dielectric screening reduces the scattering from charged impurities, but increases the scattering from short-range scatterers. We evaluate the effects of the corrugations (ripples) of graphene on SiO 2 on transport by measuring the height-height correlation function. The results show that the corrugations cannot mimic long-range (charged impurity) scattering effects, and have too small an amplitude-to-wavelength ratio to significantly affect the observed mobility via short-range scattering. Temperature-dependent measurements show that longitudinal acoustic phonons in graphene produce a resistivity that is linear in temperature and independent of carrier density; at higher temperatures, polar optical phonons of the SiO 2 substrate give rise to an activated, carrier density-dependent resistivity. Together the results paint a complete picture of charge carrier transport in graphene on SiO 2 in the diffusive regime.

  19. Dust Transport and Deposition Observed from the Terra-Moderate Image Spectrometer (MODIS) Space Observations

    Science.gov (United States)

    Kaufman, Y.

    2004-01-01

    Meteorological observations, in situ data and satellite images of dust episodes were used already in the 1970s to estimate that 100 tg of dust are transported from Africa over the Atlantic Ocean every year between June and August and deposited in the Atlantic Ocean and the Americas. Desert dust is a main source of nutrients to oceanic biota and the Amazon forest, but deteriorates air quality and caries pathogens as shown for Florida. Dust affects the Earth radiation budget, thus participating in climate change and feedback mechanisms. There is an urgent need for new tools for quantitative evaluation of the dust distribution, transport and deposition. The Terra spacecraft launched at the dawn of the last millennium provides first systematic well calibrated multispectral measurements from the MODIS instrument, for daily global analysis of aerosol. MODIS data are used here to distinguish dust from smoke and maritime aerosols and evaluate the African dust column concentration, transport and deposition. We found that 230 plus or minus 80 tg of dust are transported annually from Africa to the Atlantic Ocean, 30 tg return to Africa and Europe, 70 tg reach the Caribbean, 45 tg fertilize the Amazon Basin, 4 times as previous estimates thus explaining a paradox regarding the source of nutrition to the Amazon forest, and 120 plus or minus 40 tg are deposited in the Atlantic Ocean. The results are compared favorably with dust transport models for particle radius less than or equal to 12 microns. This study is a first example of quantitative use of MODIS aerosol for a geophysical study.

  20. Including non-public data and studies in systematic reviews and systematic maps.

    Science.gov (United States)

    Haddaway, Neal R; Collins, Alexandra M; Coughlin, Deborah; Kohl, Christian

    2017-02-01

    Systematic reviews and maps should be based on the best available evidence, and reviewers should make all reasonable efforts to source and include potentially relevant studies. However, reviewers may not be able to consider all existing evidence, since some data and studies may not be publicly available. Including non-public studies in reviews provides a valuable opportunity to increase systematic review/map comprehensiveness, potentially mitigating negative impacts of publication bias. Studies may be non-public for many reasons: some may still be in the process of being published (publication can take a long time); some may not be published due to author/publisher restrictions; publication bias may make it difficult to publish non-significant or negative results. Here, we consider what forms these non-public studies may take and the implications of including them in systematic reviews and maps. Reviewers should carefully consider the advantages and disadvantages of including non-public studies, weighing risks of bias against benefits of increased comprehensiveness. As with all systematic reviews and maps, reviewers must be transparent about methods used to obtain data and avoid risks of bias in their synthesis. We make tentative suggestions for reviewers in situations where non-public data may be present in an evidence base. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Transport relaxation measurements and glassy state effects in superconducting MgB{sub 2}

    Energy Technology Data Exchange (ETDEWEB)

    Olutas, M. [Abant Izzet Baysal University, Department of Physics, Turgut Gulez Research Laboratory, 14280 Bolu (Turkey)], E-mail: olutas_m@ibu.edu.tr; Yetis, H.; Altinkok, A.; Kilic, A.; Kilic, K. [Abant Izzet Baysal University, Department of Physics, Turgut Gulez Research Laboratory, 14280 Bolu (Turkey)

    2008-09-15

    Time dependent effects in superconducting MgB{sub 2} have been studied systematically for the first time by transport relaxation measurements (V-t curves) as a function of transport current (I), temperature (T) and external magnetic field (H). At very low dissipation levels (below {approx}1 {mu}V), it was observed that the sample voltage grows up smoothly in time by exhibiting the details of initial stage of relaxation process. At high dissipation levels, steady state corresponding to constant flow rate is maintained within a very short time and monitoring of details of flux dynamic evolving along sample becomes difficult on long time scales. Another interesting behavior is the appearance of voltage peak when the transport current was reduced to a finite value. After peak, it was observed that the sample voltage relaxes smoothly by leveling off within a very short time. The evolution of V-t curves suggests that formation of resistive flow channels along sample develops easily, which is quite similar to that of obtained for the superconducting ceramic samples whose grain boundaries are improved. Time dependent effects were also observed in magnetovoltage measurements (V-H curves) as the field sweep rate (dH/dt) varies. The observations were interpreted mainly in terms of flux trapping in grains.

  2. Multiscale pore structure and its effect on gas transport in organic-rich shale

    Science.gov (United States)

    Wu, Tianhao; Li, Xiang; Zhao, Junliang; Zhang, Dongxiao

    2017-07-01

    A systematic investigation of multiscale pore structure in organic-rich shale by means of the combination of various imaging techniques is presented, including the state-of-the-art Helium-Ion-Microscope (HIM). The study achieves insight into the major features at each scale and suggests the affordable techniques for specific objectives from the aspects of resolution, dimension, and cost. The pores, which appear to be isolated, are connected by smaller pores resolved by higher-resolution imaging. This observation provides valuable information, from the microscopic perspective of pore structure, for understanding how gas accumulates and transports from where it is generated. A comprehensive workflow is proposed based on the characteristics acquired from the multiscale pore structure analysis to simulate the gas transport process. The simulations are completed with three levels: the microscopic mechanisms should be taken into consideration at level I; the spatial distribution features of organic matter, inorganic matter, and macropores constitute the major issue at level II; and the microfracture orientation and topological structure are dominant factors at level III. The results of apparent permeability from simulations agree well with the values acquired from experiments. By means of the workflow, the impact of various gas transport mechanisms at different scales can be investigated more individually and precisely than conventional experiments.

  3. Intrinsic errors in transporting a single-spin qubit through a double quantum dot

    Science.gov (United States)

    Li, Xiao; Barnes, Edwin; Kestner, J. P.; Das Sarma, S.

    2017-07-01

    Coherent spatial transport or shuttling of a single electron spin through semiconductor nanostructures is an important ingredient in many spintronic and quantum computing applications. In this work we analyze the possible errors in solid-state quantum computation due to leakage in transporting a single-spin qubit through a semiconductor double quantum dot. In particular, we consider three possible sources of leakage errors associated with such transport: finite ramping times, spin-dependent tunneling rates between quantum dots induced by finite spin-orbit couplings, and the presence of multiple valley states. In each case we present quantitative estimates of the leakage errors, and discuss how they can be minimized. The emphasis of this work is on how to deal with the errors intrinsic to the ideal semiconductor structure, such as leakage due to spin-orbit couplings, rather than on errors due to defects or noise sources. In particular, we show that in order to minimize leakage errors induced by spin-dependent tunnelings, it is necessary to apply pulses to perform certain carefully designed spin rotations. We further develop a formalism that allows one to systematically derive constraints on the pulse shapes and present a few examples to highlight the advantage of such an approach.

  4. Falsifications and corroborations: Karl Popper's influence on systematics.

    Science.gov (United States)

    Helfenbein, Kevin G; DeSalle, Rob

    2005-04-01

    Over the last three decades, the philosophy of Karl Raimund Popper has had a strong influence on the field of systematic biology. Unequivocally, no other philosopher's work has had such an influence during this formative period in systematics. Much, but not all, of the early discourse on Popper and systematics dealt with the philosophical basis of systematics as a science. More recently Popper's work has been discussed in the systematics literature in relation to specific methodologies such as parsimony and maximum likelihood. In this paper, we provide the reader with a concise summary of Popper's ideas relevant to systematics, review the systematic literature invoking or declining Popper's importance to the field, and make a recommendation for the future course of philosophical thinking in systematics. We try to make clear various authors' interpretations of Popper's work and how those interpretations have impacted systematic thought. Although the reader may come away from this review with a clearer idea of Popper's relevance or lack thereof, our primary hope is that the reader will be compelled to question him- or herself about the philosophical basis of the systematic work that he or she does, and to delve into the literature herein cited. We begin by presenting a synopsis of Popper's philosophical views to allow those views to be placed in the context of systematics.

  5. Paleoclassical transport explains electron transport barriers in RTP and TEXTOR

    NARCIS (Netherlands)

    Hogeweij, G. M. D.; Callen, J.D.

    2008-01-01

    The recently developed paleoclassical transport model sets the minimum level of electron thermal transport in a tokamak. This transport level has proven to be in good agreement with experimental observations in many cases when fluctuation-induced anomalous transport is small, i.e. in (near-) ohmic

  6. ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI UNDERPRICING SAHAM PADA PENAWARAN SAHAM PERDANA DI BURSA EFEK INDONESIA

    Directory of Open Access Journals (Sweden)

    Reza Widhar Pahlevi

    2016-01-01

    Full Text Available Penelitian empiris ini dimaksudkan untuk mengetahui pengaruh Reputasi Underwriter, Reputasi Auditor, Persentase Saham yang ditawarkan ke Publik, Financial Leverage, Profitabilitas (ROA, Profitabilitas (NPM, Current Ratio, Ukuran Perusahaan, Umur Perusahaan, dan Jenis Industri terhadap Underpricing saham pada penawaran saham perdana di Bursa Efek Indonesia tahun 2000-2012. Berdasarkan hasil analisis data, pengujian secara parsial menunjukkan variabelvariabel Reputasi Underwriter, Reputasi Auditor, Persentase Saham yang ditawarkan ke Publik, dan Jenis Industri tidak mempunyai pengaruh yang signifikan terhadap Underpricing, Variabel Financial Leverage berpengaruh positif dan signifikan terhadap Underpricing. Sedangkan Variabel Profitabilitas (ROA, Profitabilitas (NPM, Current Ratio, Ukuran Perusahaan, dan Umur Perusahaan berpengaruh negatif dan signifikan terhadap Underpricing saham pada penawaran saham perdana di Bursa Efek Indonesia.Kata kunci : Initial Public Offering, Initial Return dan Underpricing

  7. Computational Studies of Drug Release, Transport and Absorption in the Human Intestines

    Science.gov (United States)

    Behafarid, Farhad; Brasseur, J. G.; Vijayakumar, G.; Jayaraman, B.; Wang, Y.

    2016-11-01

    Following disintegration of a drug tablet, a cloud of particles 10-200 μm in diameter enters the small intestine where drug molecules are absorbed into the blood. Drug release rate depends on particle size, solubility and hydrodynamic enhancements driven by gut motility. To quantify the interrelationships among dissolution, transport and wall permeability, we apply lattice Boltzmann method to simulate the drug concentration field in the 3D gut released from polydisperse distributions of drug particles in the "fasting" vs. "fed" motility states. Generalized boundary conditions allow for both solubility and gut wall permeability to be systematically varied. We apply a local 'quasi-steady state' approximation for drug dissolution using a mathematical model generalized for hydrodynamic enhancements and heterogeneity in drug release rate. We observe fundamental differences resulting from the interplay among release, transport and absorption in relationship to particle size distribution, luminal volume, motility, solubility and permeability. For example, whereas smaller volume encourages higher bulk concentrations and reduced release rate, it also encourages higher absorption rate, making it difficult to generalize predictions. Supported by FDA.

  8. Surveying the transportation of radioactive material (STORM) in the U.S.A

    International Nuclear Information System (INIS)

    McClure, J.D.; Hopkins, D.

    1992-01-01

    In 1988, a Technical Committee (TC-556.2) was convened by the International Atomic Energy Agency (IAEA) to advise the Agency on the collection of transport data as a means of assessing the radiological effects of radioactive material (RAM) transport. There is value in gathering such data because, from this information, Member States and the IAEA can develop environmental impact studies which demonstrate the efficacy of the packaging and transport regulations. In addition, guidance for emergency response operations can be obtained from an examination of RAM shipment patterns. Finally, there is considerable public information value to developing a compilation of the magnitude of RAM shipments on a national and international basis. This paper describes a new program, STORM, in the US to acquire RAM transport shipment data. There is presently no US national system that periodically evaluates the numbers and characteristics of RAM shipments in the United States. There have been two occasions where estimates of these numbers and characteristics have been made. These two studies estimated that there were 2.5 - 2.8 million packages shipped on an annual basis. The present data collection effort under the STORM project involves two phases. The product of Phase 1 of the STORM project is a developed survey plan to systematically update parts of the shipment data base on a periodic basis so that: (a) as much data as possible will be obtained from sources which have already collected the data for other purposes (e.g., waste burial grounds) rather than from a tedious surveying system; (b) licensees and the Federal Government can anticipate the periodic collection of data and can adjust their systems (of records, budgets, and contracts) to best accommodate that collection; (c) the shipment data base will always be reasonably up-to-date for those tasks required for continuation of the relatively free transport of radioactive material

  9. Polar transport in plants mediated by membrane transporters: focus on mechanisms of polar auxin transport.

    Science.gov (United States)

    Naramoto, Satoshi

    2017-12-01

    Directional cell-to-cell transport of functional molecules, called polar transport, enables plants to sense and respond to developmental and environmental signals. Transporters that localize to plasma membranes (PMs) in a polar manner are key components of these systems. PIN-FORMED (PIN) auxin efflux carriers, which are the most studied polar-localized PM proteins, are implicated in the polar transport of auxin that in turn regulates plant development and tropic growth. In this review, the regulatory mechanisms underlying polar localization of PINs, control of auxin efflux activity, and PIN abundance at PMs are considered. Up to date information on polar-localized nutrient transporters that regulate directional nutrient movement from soil into the root vasculature is also discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Energy policy in transport and transport policy

    International Nuclear Information System (INIS)

    Van Dender, Kurt

    2009-01-01

    Explanations for, and indirect evidence of, imperfections in the market for private passenger vehicle fuel economy suggest there is a reasonable case for combining fuel economy standards and fuel or carbon taxes to contribute to an energy policy that aims to reduce greenhouse gas emissions and improve energy security. Estimates of key elasticities, including the rebound effect, indicate that the positive and negative side-effects of fuel economy measures on transport activities and external costs are limited. However, an energy policy for transport does not replace a transport policy that aims to manage the main transport externalities including congestion and local pollution. Conventional marginal cost estimates and standard cost-benefit reasoning suggest that policies that address congestion and local pollution likely bring benefits at least as large as those from fuel economy measures. But the large uncertainty on the possible effects of greenhouse gas emissions constitutes a strong challenge for standard cost-benefit reasoning. Emerging results from methods to cope with this uncertainty suggest that policies to stimulate the widespread adoption of low-carbon technologies in transport are justified.

  11. Energy policy in transport and transport policy

    Energy Technology Data Exchange (ETDEWEB)

    Van Dender, Kurt [Joint Transport Research Centre of the International Transport Forum and the OECD, 2 rue Andre Pascale, F-75775 Paris Cedex 16 (France)

    2009-10-15

    Explanations for, and indirect evidence of, imperfections in the market for private passenger vehicle fuel economy suggest there is a reasonable case for combining fuel economy standards and fuel or carbon taxes to contribute to an energy policy that aims to reduce greenhouse gas emissions and improve energy security. Estimates of key elasticities, including the rebound effect, indicate that the positive and negative side-effects of fuel economy measures on transport activities and external costs are limited. However, an energy policy for transport does not replace a transport policy that aims to manage the main transport externalities including congestion and local pollution. Conventional marginal cost estimates and standard cost-benefit reasoning suggest that policies that address congestion and local pollution likely bring benefits at least as large as those from fuel economy measures. But the large uncertainty on the possible effects of greenhouse gas emissions constitutes a strong challenge for standard cost-benefit reasoning. Emerging results from methods to cope with this uncertainty suggest that policies to stimulate the widespread adoption of low-carbon technologies in transport are justified. (author)

  12. 25 CFR 175.23 - Customer responsibilities.

    Science.gov (United States)

    2010-04-01

    ... National Electrical Code of the National Board of Fire Underwriters for Electric Wiring and Apparatus as they apply to the installation and operation of customer-owned equipment; (b) Be responsible for...

  13. 12 CFR 1.1 - Authority, purpose, scope, and reservation of authority.

    Science.gov (United States)

    2010-01-01

    ... connection with purchasing, selling, dealing in, and underwriting securities and stock. In addition to... international activities and invest in securities pursuant to 12 CFR part 211. (d) Reservation of authority. The...

  14. SOME SYSTEMATIC SAMPLING STRATEGIES USING MULTIPLE RANDOM STARTS

    OpenAIRE

    Sampath Sundaram; Ammani Sivaraman

    2010-01-01

    In this paper an attempt is made to extend linear systematic sampling using multiple random starts due to Gautschi(1957)for various types of systematic sampling schemes available in literature, namely(i)  Balanced Systematic Sampling (BSS) of  Sethi (1965) and (ii) Modified Systematic Sampling (MSS) of Singh, Jindal, and Garg  (1968). Further, the proposed methods were compared with Yates corrected estimator developed with reference to Gautschi’s Linear systematic samplin...

  15. The Place of Railway Transport in Romania’s Transport System

    OpenAIRE

    Dãneci-Pãtrãu Daniel; Coca Carmen Elena

    2012-01-01

    The transport activity in all its forms represents one of the most complex sections of an economy, but also an important factor of influence over the quality of life, that is why current preoccupations of international organisms are oriented towards measures meant to develop performing transport systems and compatible with the environment. In the article the main activities and resources of Romania’s railway transport system are presented , the place of the railway transport in the transport ...

  16. Surrogate model approach for improving the performance of reactive transport simulations

    Science.gov (United States)

    Jatnieks, Janis; De Lucia, Marco; Sips, Mike; Dransch, Doris

    2016-04-01

    (MARS) method provides the best trade-off between speed and accuracy. This proof-of-concept forms an essential step towards building an interactive visual analytics system to enable user-driven systematic creation of geochemical surrogate models. Such a system shall enable reactive transport simulations with unprecedented spatial and temporal detail to become possible. References: Kolditz, O., Görke, U.J., Shao, H. and Wang, W., 2012. Thermo-hydro-mechanical-chemical processes in porous media: benchmarks and examples (Vol. 86). Springer Science & Business Media.

  17. On the relation between neoclassical transport and turbulent transport

    International Nuclear Information System (INIS)

    Shaing, K.C.

    2005-01-01

    It is demonstrated through the flux-force relationship in the neoclassical theory that when neoclassical transport fluxes are improved, the damping rate of the radial electric field of the zonal flow is reduced. This, in turn, leads to improved turbulent transport fluxes. Thus, two seemingly unrelated transport fluxes are intimately connected through the momentum equation, and the neoclassical flux-force relation. This also implies a method to improve turbulent transport by improving neoclassical fluxes

  18. Assessing systematic errors in GOSAT CO2 retrievals by comparing assimilated fields to independent CO2 data

    Science.gov (United States)

    Baker, D. F.; Oda, T.; O'Dell, C.; Wunch, D.; Jacobson, A. R.; Yoshida, Y.; Partners, T.

    2012-12-01

    Measurements of column CO2 concentration from space are now being taken at a spatial and temporal density that permits regional CO2 sources and sinks to be estimated. Systematic errors in the satellite retrievals must be minimized for these estimates to be useful, however. CO2 retrievals from the TANSO instrument aboard the GOSAT satellite are compared to similar column retrievals from the Total Carbon Column Observing Network (TCCON) as the primary method of validation; while this is a powerful approach, it can only be done for overflights of 10-20 locations and has not, for example, permitted validation of GOSAT data over the oceans or deserts. Here we present a complementary approach that uses a global atmospheric transport model and flux inversion method to compare different types of CO2 measurements (GOSAT, TCCON, surface in situ, and aircraft) at different locations, at the cost of added transport error. The measurements from any single type of data are used in a variational carbon data assimilation method to optimize surface CO2 fluxes (with a CarbonTracker prior), then the corresponding optimized CO2 concentration fields are compared to those data types not inverted, using the appropriate vertical weighting. With this approach, we find that GOSAT column CO2 retrievals from the ACOS project (version 2.9 and 2.10) contain systematic errors that make the modeled fit to the independent data worse. However, we find that the differences between the GOSAT data and our prior model are correlated with certain physical variables (aerosol amount, surface albedo, correction to total column mass) that are likely driving errors in the retrievals, independent of CO2 concentration. If we correct the GOSAT data using a fit to these variables, then we find the GOSAT data to improve the fit to independent CO2 data, which suggests that the useful information in the measurements outweighs the negative impact of the remaining systematic errors. With this assurance, we compare

  19. Neurotransmitter transporters

    DEFF Research Database (Denmark)

    Gether, Ulrik; Andersen, Peter H; Larsson, Orla M

    2006-01-01

    The concentration of neurotransmitters in the extracellular space is tightly controlled by distinct classes of membrane transport proteins. This review focuses on the molecular function of two major classes of neurotransmitter transporter that are present in the cell membrane of neurons and....... Recent research has provided substantial insight into the structure and function of these transporters. In particular, the recent crystallizations of bacterial homologs are of the utmost importance, enabling the first reliable structural models of the mammalian neurotransmitter transporters...

  20. Local systematic differences in 2MASS positions

    Science.gov (United States)

    Bustos Fierro, I. H.; Calderón, J. H.

    2018-01-01

    We have found that positions in the 2MASS All-sky Catalog of Point Sources show local systematic differences with characteristic length-scales of ˜ 5 to ˜ 8 arcminutes when compared with several catalogs. We have observed that when 2MASS positions are used in the computation of proper motions, the mentioned systematic differences cause systematic errors in the resulting proper motions. We have developed a method to locally rectify 2MASS with respect to UCAC4 in order to diminish the systematic differences between these catalogs. The rectified 2MASS catalog with the proposed method can be regarded as an extension of UCAC4 for astrometry with accuracy ˜ 90 mas in its positions, with negligible systematic errors. Also we show that the use of these rectified positions removes the observed systematic pattern in proper motions derived from original 2MASS positions.

  1. Secure Transportation Management

    International Nuclear Information System (INIS)

    Gibbs, P. W.

    2014-01-01

    Secure Transport Management Course (STMC) course provides managers with information related to procedures and equipment used to successfully transport special nuclear material. This workshop outlines these procedures and reinforces the information presented with the aid of numerous practical examples. The course focuses on understanding the regulatory framework for secure transportation of special nuclear materials, identifying the insider and outsider threat(s) to secure transportation, organization of a secure transportation unit, management and supervision of secure transportation units, equipment and facilities required, training and qualification needed.

  2. A systemic study of stepwise chlorination-chemical vapor transport characteristics of pure rare earth oxides from Sc2O3 to Lu2O3 mediated by alkaline chlorides as complex former

    International Nuclear Information System (INIS)

    Sun Yanhui; He Peng; Chen Huani

    2007-01-01

    A systematic study has been carried out for the stepwise chlorination-chemical vapor transport (SC-CVT) characteristics of pure rare earth oxides from Sc 2 O 3 to Lu 2 O 3 mediated by the vapor complexes KLnCl 4 and NaLnCl 4 (Ln = Sc, Y and La-Lu) used NaCl and KCl as complex former, respectively. The results showed that the SC-CVT characteristics are similarly for NaCl and KCl as complex former, the main deposition temperature of the rare earth chlorides LnCl 3 is in the increasing order ScCl 3 3 3 , and then with a systematically decreasing trend from the early lanthanide chlorides to the end one. The results also showed that the total transported amount of the produced chlorides is YCl 3 > ScCl 3 , and they are much higher than that of most lanthanoid chlorides. For lanthanoids, the total transported amount of chloride increases systematically from the early lanthanoid chlorides to the end one except for EuCl 3 and GdCl 3 mediated by KCl and NaCl as complex former, respectively, which showed the divergence effect of Gd in the total transport efficiency. But there are some differences in SC-CVT characteristics of pure rare earth oxide mediated by KCl and NaCl as complex former, that is the main deposition temperature region for the same rare earth element was lower for KCl than that for NaCl as complex former except for LaCl 3 , CeCl 3 , YbCl 3 and LuCl 3 , while the total transport amount of rare earth chloride for KCl as complex former is higher than that for NaCl except for LaCl 3 and EuCl 3 . More over, the discussion was carried out for Sc and Y on the one hand and the lanthanides contain 4f electron as another hand based on the 4f electron hybridization assumption. Further more, the transport characteristics of rare earth oxides with alkaline chlorides as complex former in this study were compared to that with AlCl 3 as complex former

  3. Perspectives of transport logistics in the railway transport enterprises

    OpenAIRE

    Elagin, Yu; Obruch, A.

    2014-01-01

    In this paper, the authors study the main directions of development of transport logistics. Identified as the main types of general transport logistics, as well as the rail sector, in which logistics acquires a dominant role in terms of reform. Also highlights the main features of transport logistics for railway transport enterprises and proved the importance of integrating function in modern conditions of development. The authors noted that to ensure the effective development of railway tran...

  4. Effectiveness of two interventions in preventing traffic accidents: a systematic review.

    Science.gov (United States)

    Porchia, B R; Baldasseroni, A; Dellisanti, C; Lorini, C; Bonaccorsi, G

    2014-01-01

    The prevention of road traffic accidents should be considered a serious public health concern, since they are the eighth leading cause of death globally and the main cause of death for young people aged 15-29. Evidences from many countries show that successes in preventing road traffic injuries can be achieved through concerted efforts at national level. The aim of our study was to assess the effectiveness of two interventions to prevent road traffic accidents: the introduction of graduated driver licensing (GDL) and the interventions to improve pedestrian and cyclist visibility. Our search started with a scoping review on the interventions to prevent road traffic accidents to allow the development of a logical framework of traffic accidents. Specific and answerable questions formulated according to PICO scheme and combinations of keywords were used to perform a systematic search in the following databases: Pubmed, Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects (DARE), Health Evidence, Transport Research International Documentation (TRID) and Google. References of selected papers were searched. Only systematic reviews and meta-analyses were eligible. No temporal limits or linguistic filters were applied. 160 systematic reviews and meta-analyses were found for the question of the introduction of GDL program and 188 on the improvement of visibility in cyclists and pedestrians. After selection, four papers were included in qualitative synthesis for each question. All included studies underwent quality evaluation. GDL programs seem to be effective in reducing crash rates among young drivers, in particular in 16 year-old. Programs with more restrictions seem also to reduce fatal events. To improve visibility of pedestrians and cyclists, street lighting has been suggested as an intervention able to improve driver's visual capabilities and ability to detect roadway hazards and to prevent car crashes. Visibility aids (fluorescent

  5. Can Communicating Personalised Disease Risk Promote Healthy Behaviour Change? A Systematic Review of Systematic Reviews.

    Science.gov (United States)

    French, David P; Cameron, Elaine; Benton, Jack S; Deaton, Christi; Harvie, Michelle

    2017-10-01

    The assessment and communication of disease risk that is personalised to the individual is widespread in healthcare contexts. Despite several systematic reviews of RCTs, it is unclear under what circumstances that personalised risk estimates promotes change in four key health-related behaviours: smoking, physical activity, diet and alcohol consumption. The present research aims to systematically identify, evaluate and synthesise the findings of existing systematic reviews. This systematic review of systematic reviews followed published guidance. A search of four databases and two-stage screening procedure with good reliability identified nine eligible systematic reviews. The nine reviews each included between three and 15 primary studies, containing 36 unique studies. Methods of personalising risk feedback included imaging/visual feedback, genetic testing, and numerical estimation from risk algorithms. The reviews were generally high quality. For a broad range of methods of estimating and communicating risk, the reviews found no evidence that risk information had strong or consistent effects on health-related behaviours. The most promising effects came from interventions using visual or imaging techniques and with smoking cessation and dietary behaviour as outcomes, but with inconsistent results. Few interventions explicitly used theory, few targeted self-efficacy or response efficacy, and a limited range of Behaviour Change Techniques were used. Presenting risk information on its own, even when highly personalised, does not produce strong effects on health-related behaviours or changes which are sustained. Future research in this area should build on the existing knowledge base about increasing the effects of risk communication on behaviour.

  6. Magnetic type transportation system

    International Nuclear Information System (INIS)

    Kobama, Masao.

    1981-01-01

    Purpose: To enable automatic transportation of nuclear substances with optional setting for the transportation distance, even for a long distance, facilitating the automation of the transportation and decreasing the space for the installation of a direction converging section of the transporting path. Constitution: A transporting vehicle having a pair of permanent magnets or ferromagnetic bodies mounted with a predetermined gap to each other along the transporting direction is provided in the transporting path including a bent direction change section for transporting specimens such as nuclear materials, and a plurality of driving vehicles having permanent magnets or ferromagnetic bodies for magnetically attracting the transporting vehicle from outside of the transporting path are arranged to the outside of the transporting path. At least one of the driving vehicles is made to run along the transporting direction of the transporting path by a driving mechanism incorporating running section such as an endless chain to drive the transportation vehicle, and the transporting vehicle is successively driven by each of the driving mechanisms. (Kawakami, Y.)

  7. The GPI transportation accounts : sustainable transportation in Halifax Regional Municipality

    Energy Technology Data Exchange (ETDEWEB)

    Savelson, A.; Colman, R.; Martin, W. [GPI Atlantic, Halifax, NS (Canada)

    2008-03-15

    The Halifax Regional Municipality (HRM) approved its first municipal planning strategy (MPS), in June 2006 that set the general framework for planning decisions over the next 20 years. The major objectives of this initiative are to manage a moderate level of population growth, minimize the environmental impact of that growth, and use it as a catalyst to make HRM more sustainable in all of its activities. Due to the dispersed nature of HRM and the diverse mix of its urban, suburban, and rural areas, the links between communities become a key focal point for sustainability measures. Transportation issues are central to many of HRM's current planning decisions and are a key component of the MPS. This report summarized the portion of the MPS that related to the development of functional transportation plans for HRM. The report also presented findings for eight key indicator categories that could be utilized to assess the sustainability of HRM's transportation system. These indicator categories include transport activity; energy consumption; greenhouse gas emissions; transportation emissions of air pollutants; land use and transportation; access to basic services; access to public transportation; neighbourhood quality of life; and household spending on transportation. The report also provided a quantitative assessment of the economic costs of passenger road transportation in HRM. The costing section provided estimates for 15 cost categories, many of which go unexamined in standard transportation accounting mechanisms. Last, a set of data and policy recommendations outlining ways to improve transportation monitoring in HRM as well as to advance the sustainability of HRM's transportation system as a whole were presented. Recommendations included: establishing settlement patterns and pedestrian or cycling-oriented infrastructure where more people could walk or cycle to work and amenities; increasing ridership by making transit accessible to a wider

  8. Systematic reviews in context: highlighting systematic reviews relevant to Africa in the Pan African Medical Journal.

    Science.gov (United States)

    Wiysonge, Charles Shey; Kamadjeu, Raoul; Tsague, Landry

    2016-01-01

    Health research serves to answer questions concerning health and to accumulate facts (evidence) required to guide healthcare policy and practice. However, research designs vary and different types of healthcare questions are best answered by different study designs. For example, qualitative studies are best suited for answering questions about experiences and meaning; cross-sectional studies for questions concerning prevalence; cohort studies for questions regarding incidence and prognosis; and randomised controlled trials for questions on prevention and treatment. In each case, one study would rarely yield sufficient evidence on which to reliably base a healthcare decision. An unbiased and transparent summary of all existing studies on a given question (i.e. a systematic review) tells a better story than any one of the included studies taken separately. A systematic review enables producers and users of research to gauge what a new study has contributed to knowledge by setting the study's findings in the context of all previous studies investigating the same question. It is therefore inappropriate to initiate a new study without first conducting a systematic review to find out what can be learnt from existing studies. There is nothing new in taking account of earlier studies in either the design or interpretation of new studies. For example, in the 18th century James Lind conducted a clinical trial followed by a systematic review of contemporary treatments for scurvy; which showed fruits to be an effective treatment for the disease. However, surveys of the peer-reviewed literature continue to provide empirical evidence that systematic reviews are seldom used in the design and interpretation of the findings of new studies. Such indifference to systematic reviews as a research function is unethical, unscientific, and uneconomical. Without systematic reviews, limited resources are very likely to be squandered on ill-conceived research and policies. In order to

  9. Identification of placental nutrient transporters associated with intrauterine growth restriction and pre-eclampsia.

    Science.gov (United States)

    Huang, Xiao; Anderle, Pascale; Hostettler, Lu; Baumann, Marc U; Surbek, Daniel V; Ontsouka, Edgar C; Albrecht, Christiane

    2018-03-02

    , molecular biological experiments and mathematical diagramming, this study has demonstrated systematic alterations of nutrient transporter expressions in IUGR/PE. Among 46 initially targeted transporters, three significantly regulated genes were further investigated based on the severity and the disease specificity for IUGR and PE. Confirmed by mRNA and protein expression, the amino acid transporters SLC7A7 and SLC38A5 showed marked differences between controls and IUGR/PE and were regulated by both diseases. In contrast, ABCA1 may play an exclusive role in the development of PE.

  10. Establishment and utilization of radiological protection programs for the transport of radioactive material

    International Nuclear Information System (INIS)

    Lopez V, J.; Capadona, N.

    2006-01-01

    The present work has by objective to indicate rules for the establishment and the use of the Radiological Protection Programs (PPR) that are of application to the transport of radioactive materials according to that required by the Transport Regulation of the International Atomic Energy Agency (IAEA). The PPR are established and applied in systematic form for remittent, transport and addressees, to consider the measures of radiological protection and its appropriately control during the transport stages of radioactive material. In particular, in the work it is analyzed the PPR applied to the operative stage, in the one that can be considered as one of the more important documents to use since it summarizes the evaluations and the necessary controls of radiological protection. Also it is analyzed the importance that this document gets ready on the base that it converges in the the analyses, evaluations and data that have been kept in mind during the previous stages of design of bundles and production of packings, the types and quantities of involved bundles, as well as of considering the quantities of expeditions and its frequencies, the ways of transport, etc. It is included a brief description of the parts that the PPR conforms on the base of that suggested in the advanced draft of the TS-G-1.5 Guide 'Radiation Protection Programmes for Transport of Radioactive Material', of October, 2005, of the IAEA: objectives. necessity, scope, basic elements of a PPR in function of the occupational dose. assignment of functions and responsibilities for the establishment of a PPR, evaluation and dose optimization, surface contamination, segregation and other protection measures, responses in emergencies. training and administration systems for baled and transport of radioactive material. Next an example of PPR for the transport of bundles of the A Type by lorry with content of radiopharmaceuticals that are the bundles more used worldwide in the expeditions of radioactive

  11. Studies on transport properties of copper doped tungsten diselenide single crystals

    Science.gov (United States)

    Deshpande, M. P.; Parmar, M. N.; Pandya, Nilesh N.; Chaki, Sunil; Bhatt, Sandip V.

    2012-02-01

    During recent years, transition metal dichalcogenides of groups IVB, VB and VIB have received considerable attention because of the great diversity in their transport properties. 2H-WSe 2 (Tungsten diselenide) is an interesting member of the transition metal dichalcogenide (TMDC's) family and known to be a semiconductor useful for photovoltaic and optoelectronic applications. The anisotropy usually observed in this diamagnetic semiconductor material is a result of the sandwich structure of Se-W-Se layers interacting with each other, loosely bonded by the weak Van der Waals forces. Recent efforts in studying the influence of the anisotropic electrical and optical properties of this layered-type transition metal dichalcogenides have been implemented by doping the samples with different alkali group elements. Unfortunately, little work is reported on doping of metals in WSe 2. Therefore, it is proposed in this work to carry out a systematic growth of single crystals of WSe 2 by doping it with copper in different proportions i.e. Cu xWSe 2 ( x=0, 0.5, 1.0) by direct vapour transport technique. Transport properties like low and high temperature resistivity measurements, high pressure resistivity, Seebeck coefficient measurements at low temperature and Hall Effect at room temperature were studied in detail on all these samples. These measurements show that tungsten diselenide single crystals are p-type whereas doped with copper makes it n-type in nature. The results obtained and their implications are discussed in this paper.

  12. Stakeholder involvement in systematic reviews: a protocol for a systematic review of methods, outcomes and effects.

    Science.gov (United States)

    Pollock, Alex; Campbell, Pauline; Struthers, Caroline; Synnot, Anneliese; Nunn, Jack; Hill, Sophie; Goodare, Heather; Watts, Chris; Morley, Richard

    2017-01-01

    Researchers are expected to actively involve stakeholders (including patients, the public, health professionals, and others) in their research. Although researchers increasingly recognise that this is good practice, there is limited practical guidance about how to involve stakeholders. Systematic reviews are a research method in which international literature is brought together, using carefully designed and rigorous methods to answer a specified question about healthcare. We want to investigate how researchers have involved stakeholders in systematic reviews, and how involvement has potentially affected the quality and impact of reviews. We plan to bring this information together by searching and reviewing the literature for reports of stakeholder involvement in systematic reviews. This paper describes in detail the methods that we plan to use to do this. After carrying out comprehensive searches for literature, we will: 1. Provide an overview of identified reports, describing key information such as types of stakeholders involved, and how. 2. Pick out reports of involvement which include detailed descriptions of how researchers involved people in a systematic review and summarise the methods they used. We will consider who was involved, how people were recruited, and how the involvement was organised and managed. 3. Bring together any reports which have explored the effect, or impact, of involving stakeholders in a systematic review. We will assess the quality of these reports, and summarise their findings. Once completed, our review will be used to produce training resources aimed at helping researchers to improve ways of involving stakeholders in systematic reviews. Background There is an expectation for stakeholders (including patients, the public, health professionals, and others) to be involved in research. Researchers are increasingly recognising that it is good practice to involve stakeholders in systematic reviews. There is currently a lack of evidence

  13. Transportation-Related Consumer Preference Data | Transportation Research |

    Science.gov (United States)

    NREL Transportation-Related Consumer Preference Data Transportation-Related Consumer Preference Data Photo of reporters test driving Toyota prototype electric and fuel cell vehicles. Consumer for the development and implementation of these technologies. NREL collects, analyzes, and reports on

  14. Resolving the mystery of transport within internal transport barriers

    Energy Technology Data Exchange (ETDEWEB)

    Staebler, G. M.; Belli, E. A.; Candy, J.; Waltz, R. E.; Greenfield, C. M.; Lao, L. L.; Smith, S. P. [General Atomics, P.O. Box 85608, San Diego, California 92186-5608 (United States); Kinsey, J. E. [CompX, P.O. Box 2672, Del Mar, California 92014-5672 (United States); Grierson, B. A. [Princeton Plasma Physics Laboratory, P.O. Box 451, Princeton, New Jersey 08543-0451 (United States); Chrystal, C. [University of California-San Diego, 9500 Gilman Dr., La Jolla, California 92093-0417 (United States)

    2014-05-15

    The Trapped Gyro-Landau Fluid (TGLF) quasi-linear model [G. M. Staebler, et al., Phys. Plasmas 12, 102508 (2005)], which is calibrated to nonlinear gyrokinetic turbulence simulations, is now able to predict the electron density, electron and ion temperatures, and ion toroidal rotation simultaneously for internal transport barrier (ITB) discharges. This is a strong validation of gyrokinetic theory of ITBs, requiring multiple instabilities responsible for transport in different channels at different scales. The mystery of transport inside the ITB is that momentum and particle transport is far above the predicted neoclassical levels in apparent contradiction with the expectation from the theory of suppression of turbulence by E×B velocity shear. The success of TGLF in predicting ITB transport is due to the inclusion of ion gyro-radius scale modes that become dominant at high E×B velocity shear and to improvements to TGLF that allow momentum transport from gyrokinetic turbulence to be faithfully modeled.

  15. Excessive sleepiness prevalence in public transportation drivers of a developing country.

    Science.gov (United States)

    Risco, Jorge; Ruiz, Paulo; Mariños, Alejandro; Juarez, Alan; Ramos, Mariana; Salmavides, Frine; Vega, Johann; Kruger, Hever; Vizcarra, Darwin

    2013-01-01

    To determine the prevalence of excessive sleepiness (ES) in bus and auto-rickshaw drivers from Lima, Peru. We conducted a cross-sectional study of Lima's bus and auto-rickshaw drivers to estimate ES prevalence in this population. Survey sites were private transportation companies, systematically selected with a snowball approach. ES was assessed with the Spanish-validated version of the Epworth sleep questionnaire (ESQ) with a cutoff score >10. We obtained relevant demographic information. Four hundred and thirty-four bus and auto-rickshaw drivers were eligible for analysis. The overall ES prevalence was 32.7 percent (95% confidence interval [CI]: 28-37.2). ES prevalence was higher in bus drivers than in auto-rickshaw drivers, 38 percent (95% CI: 31.7-44.2) and 26.9 percent (95% CI: 20.6-33.1), respectively (P = .01). We used data from all subjects to obtain regression equations for ESQ score with several predictors. Being a bus driver, working additional nighttime hours per week, having depression or anxiety, and alcohol abuse had small but significant associations with ESQ scores. ES prevalence in Lima's public transportation drivers is in a medium range as suggested by previous regional studies.

  16. Canadian pipeline transportation system : transportation assessment

    International Nuclear Information System (INIS)

    2009-07-01

    In addition to regulating the construction and operation of 70,000 km of oil and natural gas pipelines in Canada, the National Energy Board (NEB) regulates the trade of natural gas, oil and natural gas liquids. This report provided an assessment of the Canadian hydrocarbon transportation system in relation to its ability to provide a robust energy infrastructure. Data was collected from NEB-regulated pipeline companies and a range of publicly available sources to determine if adequate pipeline capacity is in place to transport products to consumers. The NEB also used throughput and capacity information received from pipeline operators as well as members of the investment community. The study examined price differentials compared with firm service tolls for transportation paths, as well as capacity utilization on pipelines and the degree of apportionment on major oil pipelines. This review indicated that in general, the Canadian pipeline transportation system continues to work effectively, with adequate pipeline capacity in place to move products to consumers who need them. 9 tabs., 30 figs., 3 appendices.

  17. Animal Transports

    Directory of Open Access Journals (Sweden)

    Diana Ludrovcová

    2016-08-01

    Full Text Available Purpose and Originality: The research is aimed to the animal transports issue, from two points of view – first is the animal cruelty and second is the policy and economic consideration. The goal is to acquaint the readers with the transports risks and its cruelty and evaluation of the economic, political aspects for he involved countries. The study is oriented on more points of view, what is rare in works with a similar theme. Method: This paper examines many issues and examinations from different authors and subsequently summarized the findings with authors own knowledge to one expanded unit. Results: Results proves, that livestock transports have negative impact on animal´s health, environment. Number of transported animals is rising every year. Society: Research familiarize the society with the animal transports, cruelty against animals during them, and influence of transports on some countries, their economy, policy. People get better informed and can form their own opinion on this topic. They may start acting, undertaking some steps to improve the present situation, what could help a lot to animals and environment. Limitations / further research: Future research could show progress and improvement of transports, quality of food supply and economics.

  18. Quality Assurance Plan for Transportation Management Division Transportation Training Programs

    International Nuclear Information System (INIS)

    1994-10-01

    The U.S. Department of Transportation (DOT) implemented new rules requiring minimum levels of training for certain key individuals who handle, package, transport, or otherwise prepare hazardous materials for transportation. In response to these rules, the U.S. Department of Energy (DOE), Transportation Management Division (TMD), has developed a transportation safety training program. This program supplies designed instructional methodology and course materials to provide basic levels of DOT training to personnel for whom training has become mandatory. In addition, this program provides advanced hazardous waste and radioactive material packaging and transportation training to help personnel achieve proficiency and/or certification as hazardous waste and radioactive material shippers. This training program does not include site-specific or task-specific training beyond DOT requirements

  19. Influence of gravity on transport and retention of representative engineered nanoparticles in quartz sand.

    Science.gov (United States)

    Cai, Li; Zhu, Jinghan; Hou, Yanglong; Tong, Meiping; Kim, Hyunjung

    2015-10-01

    Four types of NPs: carbon nanotubes and graphene oxide (carbon-based NPs), titanium dioxide and zinc oxide metal-oxide NPs, were utilized to systematically determine the influence of gravity on the transport of NPs in porous media. Packed column experiments for two types of carbon-based NPs were performed under unfavorable conditions in both up-flow (gravity-negative) and down-flow (gravity-positive) orientations, while for two types of metal-oxide NPs, experiments were performed under both unfavorable and favorable conditions in both up-flow and down-flow orientations. Both breakthrough curves and retained profiles of two types of carbon-based NPs in up-flow orientation were equivalent to those in down-flow orientation, indicating that gravity had negligible effect on the transport and retention of carbon-based NPs under unfavorable conditions. In contrast, under both unfavorable and favorable conditions, the breakthrough curves for two types of metal-oxide NPs in down-flow orientation were lower relative to those in up-flow orientation, indicating that gravity could decrease the transport of metal-oxide NPs in porous media. The distinct effect of gravity on the transport and retention of carbon-based and metal-oxide NPs was mainly attributed to the contribution of gravity to the force balance on the NPs in quartz sand. The contribution of gravity was determined by the interplay of the density and sizes of NP aggregates under examined solution conditions. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Simulation of contaminated sediment transport in White Oak Creek basin

    International Nuclear Information System (INIS)

    Bao, Y.; Clapp, R.B.; Brenkert, A.L.; Moore, T.D.; Fontaine, T.A.

    1995-01-01

    This paper presents a systematic approach to management of the contaminated sediments in the White Oak Creek watershed at Oak Ridge National Laboratory near Oak Ridge, Tennessee. The primary contaminant of concern is radioactive cesium-137 ( 137 Cs), which binds to soil and sediment particles. The key components in the approach include an intensive sampling and monitoring system for flood events; modeling of hydrological processes, sediment transport, and contaminant flux movement; and a decision framework with a detailed human health risk analysis. Emphasis is placed on modeling of watershed rainfall-runoff and contaminated sediment transport during flooding periods using the Hydrologic Simulation Program- Fortran (HSPF) model. Because a large number of parameters are required in HSPF modeling, the major effort in the modeling process is the calibration of model parameters to make simulation results and measured values agree as closely as possible. An optimization model incorporating the concepts of an expert system was developed to improve calibration results and efficiency. Over a five-year simulation period, the simulated flows match the observed values well. Simulated total amount of sediment loads at various locations during storms match with the observed values within a factor of 1.5. Simulated annual releases of 137 Cs off-site locations match the data within a factor of 2 for the five-year period. The comprehensive modeling approach can provide a valuable tool for decision makers to quantitatively analyze sediment erosion, deposition, and transport; exposure risk related to radionuclides in contaminated sediment; and various management strategies

  1. Neutron transport

    International Nuclear Information System (INIS)

    Berthoud, Georges; Ducros, Gerard; Feron, Damien; Guerin, Yannick; Latge, Christian; Limoge, Yves; Santarini, Gerard; Seiler, Jean-Marie; Vernaz, Etienne; Coste-Delclaux, Mireille; M'Backe Diop, Cheikh; Nicolas, Anne; Andrieux, Catherine; Archier, Pascal; Baudron, Anne-Marie; Bernard, David; Biaise, Patrick; Blanc-Tranchant, Patrick; Bonin, Bernard; Bouland, Olivier; Bourganel, Stephane; Calvin, Christophe; Chiron, Maurice; Damian, Frederic; Dumonteil, Eric; Fausser, Clement; Fougeras, Philippe; Gabriel, Franck; Gagnier, Emmanuel; Gallo, Daniele; Hudelot, Jean-Pascal; Hugot, Francois-Xavier; Dat Huynh, Tan; Jouanne, Cedric; Lautard, Jean-Jacques; Laye, Frederic; Lee, Yi-Kang; Lenain, Richard; Leray, Sylvie; Litaize, Olivier; Magnaud, Christine; Malvagi, Fausto; Mijuin, Dominique; Mounier, Claude; Naury, Sylvie; Nicolas, Anne; Noguere, Gilles; Palau, Jean-Marc; Le Pallec, Jean-Charles; Peneliau, Yannick; Petit, Odile; Poinot-Salanon, Christine; Raepsaet, Xavier; Reuss, Paul; Richebois, Edwige; Roque, Benedicte; Royer, Eric; Saint-Jean, Cyrille de; Santamarina, Alain; Serot, Olivier; Soldevila, Michel; Tommasi, Jean; Trama, Jean-Christophe; Tsilanizara, Aime; Behar, Christophe; Provitina, Olivier; Lecomte, Michael; Forestier, Alain; Bender, Alexandra; Parisot, Jean-Francois; Finot, Pierre

    2013-10-01

    This bibliographical note presents a reference book which addresses the study of neutron transport in matter, the study of conditions for a chain reaction and the study of modifications of matter composition due to nuclear reactions. This book presents the main nuclear data, their measurement, assessment and processing, and the spallation. It proposes an overview of methods applied for the study of neutron transport: basic equations and their derived forms, deterministic methods and Monte Carlo method of resolution of the Boltzmann equation, methods of resolution of generalized Bateman equations, methods of time resolution of space kinetics coupled equations. It presents the main calculation codes, discusses the qualification and experimental aspects, and gives an overview of neutron transport applications: neutron transport calculation of reactors, neutron transport coupled with other disciplines, physics of fuel cycle, criticality

  2. Demonstration of surface transport in a hybrid Bi2Se3/Bi2Te3 heterostructure

    OpenAIRE

    Zhao, Yanfei; Chang, Cui-Zu; Jiang, Ying; DaSilva, Ashley; Sun, Yi; Wang, Huichao; Xing, Ying; Wang, Yong; He, Ke; Ma, Xucun; Xue, Qi-Kun; Wang, Jian

    2013-01-01

    In spite of much work on topological insulators (TIs), systematic experiments for TI/TI heterostructures remain absent. We grow a high quality heterostructure containing single quintuple layer (QL) of Bi2Se3 on 19 QLs of Bi2Te3 and compare its transport properties with 20 QLs Bi2Se3 and 20 QLs Bi2Te3. All three films are grown on insulating sapphire (0001) substrates by molecular beam epitaxy (MBE). In situ angle-resolved photoemission spectroscopy (ARPES) provides direct evidence that the su...

  3. Systematic investigations of low energy Ar ion beam sputtering of Si and Ag

    Energy Technology Data Exchange (ETDEWEB)

    Feder, R., E-mail: rene.feder@iom-leipzig.de [Leibniz-Institut für Oberflächenmodifizierung, Permoserstraße 15, 04318 Leipzig (Germany); Frost, F.; Neumann, H.; Bundesmann, C.; Rauschenbach, B. [Leibniz-Institut für Oberflächenmodifizierung, Permoserstraße 15, 04318 Leipzig (Germany)

    2013-12-15

    Ion beam sputter deposition (IBD) delivers some intrinsic features influencing the growing film properties, because ion properties and geometrical process conditions generate different energy and spatial distributions of the sputtered and scattered particles. Even though IBD has been used for decades, the full capabilities are not investigated systematically and specifically used yet. Therefore, a systematic and comprehensive analysis of the correlation between the properties of the ion beam, the generated secondary particles and backscattered ions and the deposited films needs to be done. A vacuum deposition chamber has been set up which allows ion beam sputtering of different targets under variation of geometrical parameters (ion incidence angle, position of substrates and analytics in respect to the target) and of ion beam parameters (ion species, ion energy) to perform a systematic and comprehensive analysis of the correlation between the properties of the ion beam, the properties of the sputtered and scattered particles, and the properties of the deposited films. A set of samples was prepared and characterized with respect to selected film properties, such as thickness and surface topography. The experiments indicate a systematic influence of the deposition parameters on the film properties as hypothesized before. Because of this influence, the energy distribution of secondary particles was measured using an energy-selective mass spectrometer. Among others, experiments revealed a high-energetic maximum for backscattered primary ions, which shifts with increasing emission angle to higher energies. Experimental data are compared with Monte Carlo simulations done with the well-known Transport and Range of Ions in Matter, Sputtering version (TRIM.SP) code [J.P. Biersack, W. Eckstein, Appl. Phys. A: Mater. Sci. Process. 34 (1984) 73]. The thicknesses of the films are in good agreement with those calculated from simulated particle fluxes. For the positions of the

  4. 77 FR 39322 - Companies Holding Certificates of Authority as Acceptable Sureties on Federal Bonds and as...

    Science.gov (United States)

    2012-07-02

    ..., CHICAGO, IL 60604. PHONE: (312) 822-5000. UNDERWRITING LIMITATION b/: $13,107,000. SURETY LICENSES c,f... Fire and Casualty Company (NAIC 24066) BUSINESS ADDRESS: 9450 Seward Road, Fairfield, OH 45014. PHONE... 39327

  5. 46 CFR 161.006-1 - Applicable specifications.

    Science.gov (United States)

    2010-10-01

    ... Nickel Plus Chromium and Nickel Plus Chromium—161.006-4 You may obtain these standards from The American...) Underwriters' Laboratories, Inc.: Standard for flexible cord and fixture wire, third edition, October, 1935. (b...

  6. 76 FR 11542 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Order Approving...

    Science.gov (United States)

    2011-03-02

    ... Surety Association of America. Under NYSE Rule 319(a), the Stockbrokers Partnership Bond and the Brokers... disadvantage to underwriters that do not offer this type of coverage.\\26\\ The commenter further stated that...

  7. Transportation Technology: Rail Transport and Logistics

    Science.gov (United States)

    Lang, Aaron B.

    2011-01-01

    Transportation can simply be defined as the movement of goods, services, and people from one location to another. Without an efficient means to transport goods from place to place, the economy would be nothing like it is today. Throughout the history of the United States, American railroads have paved the way toward creating a nation of great…

  8. Systematic reviews in bioethics: types, challenges, and value.

    Science.gov (United States)

    McDougall, Rosalind

    2014-02-01

    There has recently been interest in applying the techniques of systematic review to bioethics literature. In this paper, I identify the three models of systematic review proposed to date in bioethics: systematic reviews of empirical bioethics research, systematic reviews of normative bioethics literature, and systematic reviews of reasons. I argue that all three types yield information useful to scholarship in bioethics, yet they also face significant challenges particularly in relation to terminology and time. Drawing on my recent experience conducting a systematic review, I suggest that complete comprehensiveness may not always be an appropriate goal of a literature review in bioethics, depending on the research question. In some cases, all the relevant ideas may be captured without capturing all the relevant literature. I conclude that systematic reviews in bioethics have an important role to play alongside the traditional broadbrush approach to reviewing literature in bioethics.

  9. First-principles study on the electronic, optical, and transport properties of monolayer α - and β -GeSe

    Science.gov (United States)

    Xu, Yuanfeng; Zhang, Hao; Shao, Hezhu; Ni, Gang; Li, Jing; Lu, Hongliang; Zhang, Rongjun; Peng, Bo; Zhu, Yongyuan; Zhu, Heyuan; Soukoulis, Costas M.

    2017-12-01

    The extraordinary properties and the novel applications of black phosphorene induce the research interest in the monolayer group-IV monochalcogenides. Here using first-principles calculations, we systematically investigate the electronic, transport, and optical properties of monolayer α - and β -GeSe, revealing a direct band gap of 1.61 eV for monolayer α -GeSe and an indirect band gap of 2.47 eV for monolayer β -GeSe. For monolayer β -GeSe, the electronic/hole transport is anisotropic, with an extremely high electron mobility of 2.93 ×104cm2/Vs along the armchair direction, comparable to that of black phosphorene. Furthermore, for β -GeSe, robust band gaps nearly independent of the applied tensile strain along the armchair direction are observed. Both monolayer α - and β -GeSe exhibit anisotropic optical absorption in the visible spectrum.

  10. Reducing uncertainty in dust monitoring to detect aeolian sediment transport responses to land cover change

    Science.gov (United States)

    Webb, N.; Chappell, A.; Van Zee, J.; Toledo, D.; Duniway, M.; Billings, B.; Tedela, N.

    2017-12-01

    Anthropogenic land use and land cover change (LULCC) influence global rates of wind erosion and dust emission, yet our understanding of the magnitude of the responses remains poor. Field measurements and monitoring provide essential data to resolve aeolian sediment transport patterns and assess the impacts of human land use and management intensity. Data collected in the field are also required for dust model calibration and testing, as models have become the primary tool for assessing LULCC-dust cycle interactions. However, there is considerable uncertainty in estimates of dust emission due to the spatial variability of sediment transport. Field sampling designs are currently rudimentary and considerable opportunities are available to reduce the uncertainty. Establishing the minimum detectable change is critical for measuring spatial and temporal patterns of sediment transport, detecting potential impacts of LULCC and land management, and for quantifying the uncertainty of dust model estimates. Here, we evaluate the effectiveness of common sampling designs (e.g., simple random sampling, systematic sampling) used to measure and monitor aeolian sediment transport rates. Using data from the US National Wind Erosion Research Network across diverse rangeland and cropland cover types, we demonstrate how only large changes in sediment mass flux (of the order 200% to 800%) can be detected when small sample sizes are used, crude sampling designs are implemented, or when the spatial variation is large. We then show how statistical rigour and the straightforward application of a sampling design can reduce the uncertainty and detect change in sediment transport over time and between land use and land cover types.

  11. Water Vapor Transport Over the Tropical Oceans During ENSO as Diagnosed from TRMM and SSM/I Data

    Science.gov (United States)

    Robertson, Franklin R.; Smith, Eric A.; Sohn, Byung-Ju

    2000-01-01

    Traditionally, large-scale water vapor transport [div Q] has been derived directly from circulation statistics in which transport processes are often depicted by mean and eddy motions. Thus detailed and accurate calculations of moisture transport terms over the globe are required. Notably, the lack of systematically spaced conventional measurements of meteorological variables over oceans has hindered understanding of the distribution and transport of water vapor. This motivates the use of indirect calculation methods in which horizontal divergence of water vapor is balanced by the evaporation minus precipitation, assuming the rate of changes of precipitable water and condensates is small over a sufficiently long time period. In order to obtain the water vapor transport, we need evaporation rate minus precipitation (E-P). Focussing on the differences in water vapor transport between El Nino and La Nina periods and their influences on atmospheric circulations, we study January, February, and March of 1998 and 1999 periods which represent El Nino and La Nina respectively. SSM/I-derived precipitation and evaporation rate from SSM/I wind and total precipitable water, in conjunction with NCEP SST and surface air temperature, are used for the calculation of the transport potential function. For the retrieval of evaporation we use a stability-dependent aerodynamic bulk scheme developed by Chou (1993). It was tested against aircraft covariance fluxes measured during cold air outbreaks over the North Atlantic Ocean. Chou et al. (1997) reported that the SSM/I retrieved latent heat flux over the western Pacific warm pool area were found to be comparable with daily mean fluxes of a ship measurements during TOGA/COARE.

  12. Optimizing literature search in systematic reviews

    DEFF Research Database (Denmark)

    Aagaard, Thomas; Lund, Hans; Juhl, Carsten Bogh

    2016-01-01

    BACKGROUND: When conducting systematic reviews, it is essential to perform a comprehensive literature search to identify all published studies relevant to the specific research question. The Cochrane Collaborations Methodological Expectations of Cochrane Intervention Reviews (MECIR) guidelines...... of musculoskeletal disorders. METHODS: Data sources were systematic reviews published by the Cochrane Musculoskeletal Review Group, including at least five RCTs, reporting a search history, searching MEDLINE, EMBASE, CENTRAL, and adding reference- and hand-searching. Additional databases were deemed eligible...... if they indexed RCTs, were in English and used in more than three of the systematic reviews. Relative recall was calculated as the number of studies identified by the literature search divided by the number of eligible studies i.e. included studies in the individual systematic reviews. Finally, cumulative median...

  13. Using Multiple Types of Studies in Systematic Reviews of Health Care Interventions – A Systematic Review

    Science.gov (United States)

    Peinemann, Frank; Tushabe, Doreen Allen; Kleijnen, Jos

    2013-01-01

    Background A systematic review may evaluate different aspects of a health care intervention. To accommodate the evaluation of various research questions, the inclusion of more than one study design may be necessary. One aim of this study is to find and describe articles on methodological issues concerning the incorporation of multiple types of study designs in systematic reviews on health care interventions. Another aim is to evaluate methods studies that have assessed whether reported effects differ by study types. Methods and Findings We searched PubMed, the Cochrane Database of Systematic Reviews, and the Cochrane Methodology Register on 31 March 2012 and identified 42 articles that reported on the integration of single or multiple study designs in systematic reviews. We summarized the contents of the articles qualitatively and assessed theoretical and empirical evidence. We found that many examples of reviews incorporating multiple types of studies exist and that every study design can serve a specific purpose. The clinical questions of a systematic review determine the types of design that are necessary or sufficient to provide the best possible answers. In a second independent search, we identified 49 studies, 31 systematic reviews and 18 trials that compared the effect sizes between randomized and nonrandomized controlled trials, which were statistically different in 35%, and not different in 53%. Twelve percent of studies reported both, different and non-different effect sizes. Conclusions Different study designs addressing the same question yielded varying results, with differences in about half of all examples. The risk of presenting uncertain results without knowing for sure the direction and magnitude of the effect holds true for both nonrandomized and randomized controlled trials. The integration of multiple study designs in systematic reviews is required if patients should be informed on the many facets of patient relevant issues of health care

  14. Enhanced flux pinning in MOCVD-YBCO films through Zr additions : systematic feasibility studies.

    Energy Technology Data Exchange (ETDEWEB)

    Aytug, T.; Paranthaman, M.; Specht, E. D.; Zhang, Y.; Kim, K.; Zuev, Y. L.; Cantoni, C.; Goyal, A.; Christen, D. K.; Maroni, V. A.; Chen, Y.; Selvamanickam, V.; ORNL; SuperPower, Inc.

    2010-01-01

    Systematic effects of Zr additions on the structural and flux pinning properties of YBa{sub 2}Cu{sub 3}O{sub 7-{delta}} (YBCO) films deposited by metal-organic chemical vapor deposition (MOCVD) have been investigated. Detailed characterization, conducted by coordinated transport, x-ray diffraction, scanning and transmission electron microscopy analyses, and imaging Raman microscopy have revealed trends in the resulting property/performance correlations of these films with respect to varying mole percentages (mol%) of added Zr. For compositions {le} 7.5 mol%, Zr additions lead to improved in-field critical current density, as well as extra correlated pinning along the c-axis direction of the YBCO films via the formation of columnar, self-assembled stacks of BaZrO{sub 3} nanodots.

  15. Enhanced flux pinning in MOCVD-YBCO films through Zr additions: systematic feasibility studies

    Energy Technology Data Exchange (ETDEWEB)

    Aytug, T; Paranthaman, M; Specht, E D; Zhang, Y; Kim, K; Zuev, Y L; Cantoni, C; Goyal, A; Christen, D K [Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States); Maroni, V A [Argonne National Laboratory, Argonne, IL 60439 (United States); Chen, Y; Selvamanickam, V, E-mail: aytugt@ornl.go [SuperPower, Incorporated, 450 Duane Avenue, Schenectady, NY 12304 (United States)

    2010-01-15

    Systematic effects of Zr additions on the structural and flux pinning properties of YBa{sub 2}Cu{sub 3}O{sub 7-{delta}} (YBCO) films deposited by metal-organic chemical vapor deposition (MOCVD) have been investigated. Detailed characterization, conducted by coordinated transport, x-ray diffraction, scanning and transmission electron microscopy analyses, and imaging Raman microscopy have revealed trends in the resulting property/performance correlations of these films with respect to varying mole percentages (mol%) of added Zr. For compositions {<=}7.5 mol%, Zr additions lead to improved in-field critical current density, as well as extra correlated pinning along the c-axis direction of the YBCO films via the formation of columnar, self-assembled stacks of BaZrO{sub 3} nanodots.

  16. Health literacy in type 2 diabetes patients: a systematic review of systematic reviews.

    Science.gov (United States)

    Caruso, Rosario; Magon, Arianna; Baroni, Irene; Dellafiore, Federica; Arrigoni, Cristina; Pittella, Francesco; Ausili, Davide

    2018-01-01

    Aim To summarize, critically review, and interpret the evidence related to the systematic reviews on health literacy (HL) amongst type 2 diabetes mellitus (T2DM). Methods The methodology for this study consisted of a systematic review of systematic reviews, using the PRISMA statement and flowchart to select studies, and searching on PubMed, CINAHL, Scopus, and Cochrane. The search covered the period between January 2006 and June 2016. Results From the 115 identified record by the queries, only six systematic reviews were included, following a quality evaluation using AMSTAR. The included systematic reviews content was analyzed by the independent work of two authors, using a narrative synthesis approach. The findings of this study (i.e., main themes) are areas of consensus and gaps in knowledge. Areas of consensus are HL definition, HL measurement tools, and the relationship between T2DM patient knowledge (or literacy) and his/her HL. The gaps in knowledge were the assessment of the relations between HL and health outcomes and self-efficacy, the gender differences, the effectiveness of interventions to improve HL, the cost-effectiveness study of interventions to improve HL, and the understanding of the influence of organizational environment on HL. Conclusion This review provides a current state of knowledge to address clinical practice and research proposals. HL could be useful to personalize patients' follow-up and it should be routinely assessed in its three dimensions (i.e. functional, interactive and critical) to enhance patients' ability to cope with clinical recommendations. Future research should be mainly aimed to test the effectiveness of evidence-based interventions to improve HL amongst T2DM patients.

  17. Instrumental systematics and weak gravitational lensing

    International Nuclear Information System (INIS)

    Mandelbaum, R.

    2015-01-01

    We present a pedagogical review of the weak gravitational lensing measurement process and its connection to major scientific questions such as dark matter and dark energy. Then we describe common ways of parametrizing systematic errors and understanding how they affect weak lensing measurements. Finally, we discuss several instrumental systematics and how they fit into this context, and conclude with some future perspective on how progress can be made in understanding the impact of instrumental systematics on weak lensing measurements

  18. Systems with a constant heat flux with applications to radiative heat transport across nanoscale gaps and layers

    Science.gov (United States)

    Budaev, Bair V.; Bogy, David B.

    2018-06-01

    We extend the statistical analysis of equilibrium systems to systems with a constant heat flux. This extension leads to natural generalizations of Maxwell-Boltzmann's and Planck's equilibrium energy distributions to energy distributions of systems with a net heat flux. This development provides a long needed foundation for addressing problems of nanoscale heat transport by a systematic method based on a few fundamental principles. As an example, we consider the computation of the radiative heat flux between narrowly spaced half-spaces maintained at different temperatures.

  19. US policies to enhance older driver safety: a systematic review of the literature.

    Science.gov (United States)

    Dugan, Elizabeth; Barton, Kelli N; Coyle, Caitlin; Lee, Chae Man

    2013-01-01

    The purpose of this study was to conduct a systematic review of the literature related to state policies concerning older drivers and to draw policy conclusions about which policies appear to work to reduce older driver crashes and to identify areas needed for further research. Specific policies examined in this paper concern medical reporting and medical review, license renewal processes, and driver testing. A study was included in the systematic review if it met the following criteria: published in English between 1991and January 2013; included data on human subjects aged 65 and older residing in the United States; included information on at least one policy related to older drivers; and had a transportation-related outcome variable (e.g., crash, fatality, renewal). A total of 29 studies met inclusion criteria. Twenty-two studies investigated license renewal and seven articles examined medical reporting. In-person license renewal requirements were associated with reduced risk for fatal crashes. Restricted licenses were associated with reduced number of miles driven per week. More intensive renewal requirements and being the subject of a medical report to the licensing authority was associated with delicensure. Given the importance of driving to mobility, quality of life, and public safety, more research is needed.

  20. The developmental effects of pentachlorophenol on zebrafish embryos during segmentation: A systematic view

    Science.gov (United States)

    Xu, Ting; Zhao, Jing; Xu, Zhifa; Pan, Ruijie; Yin, Daqiang

    2016-05-01

    Pentachlorophenol (PCP) is a typical toxicant and prevailing pollutant whose toxicity has been broadly investigated. However, previous studies did not specifically investigate the underlying mechanisms of its developmental toxicity. Here, we chose zebrafish embryos as the model, exposed them to 2 different concentrations of PCP, and sequenced their entire transcriptomes at 10 and 24 hours post-fertilization (hpf). The sequencing analysis revealed that high concentrations of PCP elicited systematic responses at both time points. By combining the enrichment terms with single genes, the results were further analyzed using three categories: metabolism, transporters, and organogenesis. Hyperactive glycolysis was the most outstanding feature of the transcriptome at 10 hpf. The entire system seemed to be hypoxic, although hypoxia-inducible factor-1α (HIF1α) may have been suppressed by the upregulation of prolyl hydroxylase domain enzymes (PHDs). At 24 hpf, PCP primarily affected somitogenesis and lens formation probably resulting from the disruption of embryonic body plan at earlier stages. The proposed underlying toxicological mechanism of PCP was based on the crosstalk between each clue. Our study attempted to describe the developmental toxicity of environmental pollutants from a systematic view. Meanwhile, some features of gene expression profiling could serve as markers of human health or ecological risk.

  1. A systematic approach for future solid waste cleanup activities at the Hanford Site

    International Nuclear Information System (INIS)

    Dirks, L.L.; Konynenbelt, H.S.; Hladek, K.L.

    1995-02-01

    This paper describes the systematic approach to the treatment, storage, and disposal system (TSD) planning and management that has been developed and implemented by Hanford's Solid Waste Program. The systematic approach includes: collecting the forecast and waste inventory data; defining Hanford's TSD system; studying and refining the TSD system by using analysis tools; and documenting analysis results. The customers responsible for planning, funding, and managing future solid waste activities have driven the evolution of the solid waste system. Currently, all treatment facilities are several years from operating. As these facilities become closer to reality, more detailed systems analysis and modeling will be necessary to successfully remediate solid waste at the Site. The tools will continue to be developed in detail to address the complexities of the system as they become better defined. The tools will help determine which facility lay-outs are most optimal, will help determine what types of equipment should be used to optimize the transport of materials to and from each TSD facility, and will be used for performing life-cycle analysis. It is envisioned that in addition to developing the tools to be adapted to the more specific facility design issues, this approach will also be used as an example for other waste installations across the DOE complex

  2. Effect of ambient on electrical transport properties of ultra-thin Au nanowires

    Science.gov (United States)

    Amin, Kazi Rafsanjani; Kundu, Subhajit; Biswas, Sangram; Roy, Ahin; Singh, Abhishek Kumar; Ravishankar, N.; Bid, Aveek

    2016-12-01

    In this letter we present systematic studies of the dynamics of surface adsorption of various chemicals on ultra-thin single crystalline gold nanowires (AuNW) through sensitive resistance fluctuation spectroscopy measurements coupled with ab initio simulations. We show that, contrary to expectations, the adsorption of common chemicals like methanol and acetone has a profound impact on the electrical transport properties of the AuNW. Our measurements and subsequent calculations establish conclusively that in AuNW, semiconductor-like sensitivity to the ambient arises because of changes induced in its local density of states by the surface adsorbed molecules. The extreme sensitivity of the resistance fluctuations of the AuNW to ambient suggests their possible use as solid-state sensors.

  3. Nuclear transport

    International Nuclear Information System (INIS)

    Anon.

    2003-01-01

    During january and february 2003, a unique event concerning nuclear transport was reported and rated 1 on the INES scale. This event concerns the absence of a maintenance operation on a shipping cask. This shipping cask was used for several years for nuclear transport inside La-hague site before being re-assigned to transport on public thoroughfare. The re-assignment of the cask should have been preceded and conditioned by a maintenance operation whose purpose is to check the efficiency of its radiation shield. During this period 2 on-site inspections concerning the transport of nuclear materials were performed. (A.C.)

  4. Systematic review

    DEFF Research Database (Denmark)

    Bager, Palle; Chauhan, Usha; Greveson, Kay

    2017-01-01

    of evidence is needed and the aim of this article was to systematically review the evidence of IBD advice lines. MATERIALS AND METHODS: A broad systematic literature search was performed to identify relevant studies addressing the effect of advice lines. The process of selection of the retrieved studies...... was undertaken in two phases. In phase one, all abstracts were review by two independent reviewers. In phase two, the full text of all included studies were independently reviewed by two reviewers. The included studies underwent quality assessment and data synthesis. RESULTS: Ten published studies and 10...... congress abstracts were included in the review. The studies were heterogeneous both in scientific quality and in the focus of the study. No rigorous evidence was found to support that advice lines improve disease activity in IBD and correspondingly no studies reported worsening in disease activity. Advice...

  5. Sediment Transport Study in Haeundae Beach using Radioisotope Labelled Compound

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jin Seop; Kim, Jong Bum; Jung, Sung Hee [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of); Lee, Jong Sup [Pukyong National Univ., Busan (Korea, Republic of)

    2005-07-01

    Haeundae beach is one of the most famous resorts in Korea and plays an important role as a special tourism district. However, the length and width of the beach are being reduced continuously, which would have bad influence on the regional economy and be the financial burden to the local authority considering that a large amount of budget is spent in the beach nourishment annually. Hence, it is necessary to understand the dynamic behavior of sediments in the coast for the systematic preservation plan of coastal environment. Lately a monitoring system using radioactive isotope as tracers is considered as a novel technique in understanding the dynamic transport of sediments. The objective of this study is to investigate the possible variations in sedimentary distribution and quantify the characteristics of sediments using radiotracer.

  6. Sediment Transport Study in Haeundae Beach using Radioisotope Labelled Compound

    International Nuclear Information System (INIS)

    Kim, Jin Seop; Kim, Jong Bum; Jung, Sung Hee; Lee, Jong Sup

    2005-01-01

    Haeundae beach is one of the most famous resorts in Korea and plays an important role as a special tourism district. However, the length and width of the beach are being reduced continuously, which would have bad influence on the regional economy and be the financial burden to the local authority considering that a large amount of budget is spent in the beach nourishment annually. Hence, it is necessary to understand the dynamic behavior of sediments in the coast for the systematic preservation plan of coastal environment. Lately a monitoring system using radioactive isotope as tracers is considered as a novel technique in understanding the dynamic transport of sediments. The objective of this study is to investigate the possible variations in sedimentary distribution and quantify the characteristics of sediments using radiotracer

  7. A Critical Review of Search Strategies Used in Recent Systematic Reviews Published in Selected Prosthodontic and Implant-Related Journals: Are Systematic Reviews Actually Systematic?

    Science.gov (United States)

    Layton, Danielle

    The aim of this study was to outline how search strategies can be systematic, to examine how the searches in recent systematic reviews in prosthodontic and implant-related journals were structured, and to determine whether the search strategies used in those articles were systematic. A total of 103 articles published as systematic reviews and indexed in Medline between January 2013 and May 2016 were identified from eight prosthodontic and implant journals and reviewed. The search strategies were considered systematic when they met the following criteria: (1) more than one electronic database was searched, (2) more than one searcher was clearly involved, (3) both text words and indexing terms were clearly included in the search strategy, (4) a hand search of selected journals or reference lists was undertaken, (5) gray research was specifically sought, and (6) the articles were published in English and at least one other language. The data were tallied and qualitatively assessed. The majority of articles reported on implants (54%), followed by tooth-supported fixed prosthodontics (13%). A total of 23 different electronic resources were consulted, including Medline (by 100% of articles), the Cochrane Library (52%), and Embase (37%). The majority consulted more than one electronic resource (71%), clearly included more than one searcher (73%), and employed a hand search of either selected journals or reference lists (86%). Less than half used both text words and indexing terms to identify articles (42%), while 15% actively sought gray research. Articles published in languages other than English were considered in 63 reviews, but only 14 had no language restrictions. Of the 103 articles, 5 completed search strategies that met all 6 criteria, and a further 12 met 5 criteria. Two articles did not fulfill any of the criteria. More than 95% of recent prosthodontic and implant review articles published in the selected journals failed to use search strategies that were

  8. An environment-dependent semi-empirical tight binding model suitable for electron transport in bulk metals, metal alloys, metallic interfaces, and metallic nanostructures. II. Application—Effect of quantum confinement and homogeneous strain on Cu conductance

    Science.gov (United States)

    Hegde, Ganesh; Povolotskyi, Michael; Kubis, Tillmann; Charles, James; Klimeck, Gerhard

    2014-03-01

    The Semi-Empirical tight binding model developed in Part I Hegde et al. [J. Appl. Phys. 115, 123703 (2014)] is applied to metal transport problems of current relevance in Part II. A systematic study of the effect of quantum confinement, transport orientation, and homogeneous strain on electronic transport properties of Cu is carried out. It is found that quantum confinement from bulk to nanowire boundary conditions leads to significant anisotropy in conductance of Cu along different transport orientations. Compressive homogeneous strain is found to reduce resistivity by increasing the density of conducting modes in Cu. The [110] transport orientation in Cu nanowires is found to be the most favorable for mitigating conductivity degradation since it shows least reduction in conductance with confinement and responds most favorably to compressive strain.

  9. An environment-dependent semi-empirical tight binding model suitable for electron transport in bulk metals, metal alloys, metallic interfaces, and metallic nanostructures. II. Application—Effect of quantum confinement and homogeneous strain on Cu conductance

    International Nuclear Information System (INIS)

    Hegde, Ganesh; Povolotskyi, Michael; Kubis, Tillmann; Charles, James; Klimeck, Gerhard

    2014-01-01

    The Semi-Empirical tight binding model developed in Part I Hegde et al. [J. Appl. Phys. 115, 123703 (2014)] is applied to metal transport problems of current relevance in Part II. A systematic study of the effect of quantum confinement, transport orientation, and homogeneous strain on electronic transport properties of Cu is carried out. It is found that quantum confinement from bulk to nanowire boundary conditions leads to significant anisotropy in conductance of Cu along different transport orientations. Compressive homogeneous strain is found to reduce resistivity by increasing the density of conducting modes in Cu. The [110] transport orientation in Cu nanowires is found to be the most favorable for mitigating conductivity degradation since it shows least reduction in conductance with confinement and responds most favorably to compressive strain

  10. An environment-dependent semi-empirical tight binding model suitable for electron transport in bulk metals, metal alloys, metallic interfaces, and metallic nanostructures. II. Application—Effect of quantum confinement and homogeneous strain on Cu conductance

    Energy Technology Data Exchange (ETDEWEB)

    Hegde, Ganesh, E-mail: ghegde@purdue.edu; Povolotskyi, Michael; Kubis, Tillmann; Charles, James; Klimeck, Gerhard, E-mail: gekco@purdue.edu [Network for Computational Nanotechnology (NCN), Department of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana 47907 (United States)

    2014-03-28

    The Semi-Empirical tight binding model developed in Part I Hegde et al. [J. Appl. Phys. 115, 123703 (2014)] is applied to metal transport problems of current relevance in Part II. A systematic study of the effect of quantum confinement, transport orientation, and homogeneous strain on electronic transport properties of Cu is carried out. It is found that quantum confinement from bulk to nanowire boundary conditions leads to significant anisotropy in conductance of Cu along different transport orientations. Compressive homogeneous strain is found to reduce resistivity by increasing the density of conducting modes in Cu. The [110] transport orientation in Cu nanowires is found to be the most favorable for mitigating conductivity degradation since it shows least reduction in conductance with confinement and responds most favorably to compressive strain.

  11. Reduced dopamine receptors and transporters but not synthesis capacity in normal aging adults: a meta-analysis.

    Science.gov (United States)

    Karrer, Teresa M; Josef, Anika K; Mata, Rui; Morris, Evan D; Samanez-Larkin, Gregory R

    2017-09-01

    Many theories of cognitive aging are based on evidence that dopamine (DA) declines with age. Here, we performed a systematic meta-analysis of cross-sectional positron emission tomography and single-photon emission-computed tomography studies on the average effects of age on distinct DA targets (receptors, transporters, or relevant enzymes) in healthy adults (N = 95 studies including 2611 participants). Results revealed significant moderate to large, negative effects of age on DA transporters and receptors. Age had a significantly larger effect on D1- than D2-like receptors. In contrast, there was no significant effect of age on DA synthesis capacity. The average age reductions across the DA system were 3.7%-14.0% per decade. A meta-regression found only DA target as a significant moderator of the age effect. This study precisely quantifies prior claims of reduced DA functionality with age. It also identifies presynaptic mechanisms (spared synthesis capacity and reduced DA transporters) that may partially account for previously unexplained phenomena whereby older adults appear to use dopaminergic resources effectively. Recommendations for future studies including minimum required samples sizes are provided. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

  12. Interventions to Reduce Adult Nursing Turnover: A Systematic Review of Systematic Reviews.

    Science.gov (United States)

    Halter, Mary; Pelone, Ferruccio; Boiko, Olga; Beighton, Carole; Harris, Ruth; Gale, Julia; Gourlay, Stephen; Drennan, Vari

    2017-01-01

    Nurse turnover is an issue of concern in health care systems internationally. Understanding which interventions are effective to reduce turnover rates is important to managers and health care organisations. Despite a plethora of reviews of such interventions, strength of evidence is hard to determine. We aimed to review literature on interventions to reduce turnover in nurses working in the adult health care services in developed economies. We conducted an overview (systematic review of systematic reviews) using the Cochrane Database of Systematic Reviews, MEDLINE, EMBASE, Applied Social Sciences Index and Abstracts, CINAHL plus and SCOPUS and forward searching. We included reviews published between 1990 and January 2015 in English. We carried out parallel blinded selection, extraction of data and assessment of bias, using the Assessment of Multiple Systematic Reviews. We carried out a narrative synthesis. Despite the large body of published reviews, only seven reviews met the inclusion criteria. These provide moderate quality review evidence, albeit from poorly controlled primary studies. They provide evidence of effect of a small number of interventions which decrease turnover or increase retention of nurses, these being preceptorship of new graduates and leadership for group cohesion. We highlight that a large body of reviews does not equate with a large body of high quality evidence. Agreement as to the measures and terminology to be used together with well-designed, funded primary research to provide robust evidence for nurse and human resource managers to base their nurse retention strategies on is urgently required.

  13. Reporting and Handling Missing Outcome Data in Mental Health: A Systematic Review of Cochrane Systematic Reviews and Meta-Analyses

    Science.gov (United States)

    Spineli, Loukia M.; Pandis, Nikolaos; Salanti, Georgia

    2015-01-01

    Objectives: The purpose of the study was to provide empirical evidence about the reporting of methodology to address missing outcome data and the acknowledgement of their impact in Cochrane systematic reviews in the mental health field. Methods: Systematic reviews published in the Cochrane Database of Systematic Reviews after January 1, 2009 by…

  14. Interventions to improve work outcomes in work-related PTSD: a systematic review

    Directory of Open Access Journals (Sweden)

    Bonato Sarah

    2011-10-01

    Full Text Available Abstract Background Posttraumatic stress disorder acquired at work can be debilitating both for workers and their employers. The disorder can result in increased sick leave, reduced productivity, and even unemployment. Furthermore, workers are especially unlikely to return to their previous place of employment after a traumatic incident at work because of the traumatic memories and symptoms of avoidance that typically accompany the disorder. Therefore, intervening in work-related PTSD becomes especially important in order to get workers back to the workplace. Methods A systematic literature search was conducted using Medline, PsycINFO, Embase, and Web of Science. The articles were independently screened based on inclusion and exclusion criteria, followed by a quality assessment of all included articles. Results The systematic search identified seven articles for inclusion in the review. These consisted of six research articles and one systematic review. The review focused specifically on interventions using real exposure techniques for anxiety disorders in the workplace. In the research articles addressed in the current review, study populations included police officers, public transportation workers, and employees injured at work. The studies examined the effectiveness of EMDR, cognitive-behavioural techniques, and an integrative therapy approach called brief eclectic psychotherapy. Interestingly, 2 of the 6 research articles addressed add-on treatments for workplace PTSD, which were designed to treat workers with PTSD who failed to respond to traditional evidence-based psychotherapy. Conclusions Results of the current review suggest that work-related interventions show promise as effective strategies for promoting return to work in employees who acquired PTSD in the workplace. Further research is needed in this area to determine how different occupational groups with specific types of traumatic exposure might respond differently to work

  15. The difficulties of systematic reviews.

    Science.gov (United States)

    Westgate, Martin J; Lindenmayer, David B

    2017-10-01

    The need for robust evidence to support conservation actions has driven the adoption of systematic approaches to research synthesis in ecology. However, applying systematic review to complex or open questions remains challenging, and this task is becoming more difficult as the quantity of scientific literature increases. We drew on the science of linguistics for guidance as to why the process of identifying and sorting information during systematic review remains so labor intensive, and to provide potential solutions. Several linguistic properties of peer-reviewed corpora-including nonrandom selection of review topics, small-world properties of semantic networks, and spatiotemporal variation in word meaning-greatly increase the effort needed to complete the systematic review process. Conversely, the resolution of these semantic complexities is a common motivation for narrative reviews, but this process is rarely enacted with the rigor applied during linguistic analysis. Therefore, linguistics provides a unifying framework for understanding some key challenges of systematic review and highlights 2 useful directions for future research. First, in cases where semantic complexity generates barriers to synthesis, ecologists should consider drawing on existing methods-such as natural language processing or the construction of research thesauri and ontologies-that provide tools for mapping and resolving that complexity. These tools could help individual researchers classify research material in a more robust manner and provide valuable guidance for future researchers on that topic. Second, a linguistic perspective highlights that scientific writing is a rich resource worthy of detailed study, an observation that can sometimes be lost during the search for data during systematic review or meta-analysis. For example, mapping semantic networks can reveal redundancy and complementarity among scientific concepts, leading to new insights and research questions. Consequently

  16. Solutions to Improve Person Transport System in the Pitesti City by Analyzing Public Transport vs. Private Transport

    Science.gov (United States)

    Mihaela, Istrate; Alexandru, Boroiu; Viorel, Nicolae; Ionel, Vieru

    2017-10-01

    One of the major problems facing the Pitesti city is the road congestion that occurs in the central area of the city during the peak hours. With all the measures taken in recent years - the widening of road arteries, increasing the number of parking spaces, the creation of overground road passages - it is obvious that the problem can only be solved by a new philosophy regarding urban mobility: it is no longer possible to continue through solutions to increase the accessibility of the central area of the city, but it is necessary, on the contrary, to promote a policy of discouraging the penetration of vehicles in the city center, coupled with a policy of improving the connection between urban public transport and county public transport. This new approach is also proposed in the new Urban Mobility Plan of Pitesti city, under development. The most convincing argument for the necessity of this new orientation in the Pitesti city mobility plan is based on the analysis of the current situation of passenger transport on the territory of Pitesti city: the analysis of “public transport versus private transport” reveals a very low occupancy rate for cars and the fact that the road surface required for a passenger (the dynamic area) is much higher in the case of private transport than in the case of public transport. Measurements of passenger flows and vehicle flows on the 6 penetration ways in the city have been made and the calculations clearly demonstrate the benefits of an urban public transport system connected by “transshipment buses” to be made at the edge of the city, to the county public transport system. In terms of inter-county transport, it will continue to be connected to the urban public transport system by existing bus Station, within the city: South Bus Station and North Bus Station. The usefulness of the paper is that it identifies the solutions for sustainable mobility in Pitesti city and proposes concrete solutions for the development of the

  17. Paleoclassical transport explains electron transport barriers in RTP and TEXTOR

    Energy Technology Data Exchange (ETDEWEB)

    Hogeweij, G M D [FOM-Institute for Plasma Physics Rijnhuizen, Association EURATOM-FOM, PO Box 1207, NL-3430 BE Nieuwegein (Netherlands); Callen, J D [University of Wisconsin, Madison, WI 53706-1609 (United States)

    2008-06-15

    The recently developed paleoclassical transport model sets the minimum level of electron thermal transport in a tokamak. This transport level has proven to be in good agreement with experimental observations in many cases when fluctuation-induced anomalous transport is small, i.e. in (near-)ohmic plasmas in small to medium size tokamaks, inside internal transport barriers (ITBs) or edge transport barriers (H-mode pedestal). In this paper predictions of the paleoclassical transport model are compared in detail with data from such kinds of discharges: ohmic discharges from the RTP tokamak, EC heated RTP discharges featuring both dynamic and shot-to-shot scans of the ECH power deposition radius and off-axis EC heated discharges from the TEXTOR tokamak. For ohmically heated RTP discharges the T{sub e} profiles predicted by the paleoclassical model are in reasonable agreement with the experimental observations, and various parametric dependences are captured satisfactorily. The electron thermal ITBs observed in steady state EC heated RTP discharges and transiently after switch-off of off-axis ECH in TEXTOR are predicted very well by the paleoclassical model.

  18. Germany: Exposure of Transport Workers During the Transport of Most Frequently Transported NORM in Germany

    International Nuclear Information System (INIS)

    2013-01-01

    The German national report to this CRP was focused on the following services according to the research agreement: (1) Status review, analysis and evaluation of the radiation exposure imposed by shipment and expected exposure of the shipment staff of the most relevant NORM in Germany; (2) Development of evaluation criteria and safety requirements to provide adequate safety standards for the transportation of NORM; (3) Development and application of procedures to determine the limits for exempt materials/consignments for transportation according to German Transport Regulations for all NORM. For the analysis and evaluation of the radiation exposure imposed by shipment of NORM for the following materials, a couple of transport scenarios were defined and the dose to transport workers was calculated. - Tantalum raw materials; - Raw phosphate; - Pipe scales and sludge from oil and gas exploitation; - Coal ash; - Waste rock material from uranium mining; - Zircon raw materials; - Titanium dioxide raw materials; - Filter gravel from waterworks

  19. FraudBuster: Reducing Fraud in an Auto Insurance Market.

    Science.gov (United States)

    Nagrecha, Saurabh; Johnson, Reid A; Chawla, Nitesh V

    2018-03-01

    Nonstandard insurers suffer from a peculiar variant of fraud wherein an overwhelming majority of claims have the semblance of fraud. We show that state-of-the-art fraud detection performs poorly when deployed at underwriting. Our proposed framework "FraudBuster" represents a new paradigm in predicting segments of fraud at underwriting in an interpretable and regulation compliant manner. We show that the most actionable and generalizable profile of fraud is represented by market segments with high confidence of fraud and high loss ratio. We show how these segments can be reported in terms of their constituent policy traits, expected loss ratios, support, and confidence of fraud. Overall, our predictive models successfully identify fraud with an area under the precision-recall curve of 0.63 and an f-1 score of 0.769.

  20. Impact of standards and certification on environmental impairment liability insurance programs

    International Nuclear Information System (INIS)

    Gulledge, W.P.

    1993-01-01

    Environmental impairment liability (EIL) insurance is available for petroleum storage tank and other environmental exposures. Recent standards and performance criteria for leak detection for underground storage tanks (USTs) and other technical standards for USTs have been both a benefit and an interference to risk-based underwriting of storage tank EIL insurance programs. Insurance underwriters and state financial responsibility program administrators are confronted with confusing information to manage these environmental risks. Standards and certification are also key issues for site assessment programs. Recent activities from ASTM and the Institute for Environmental Auditing (IEA) have addressed the need to increase the professional stature of site assessments and environmental management. Reaction and acceptance of these efforts by the users have been mixed. Ultimately, these efforts will greatly impact insurance coverage for environmental risks

  1. Systematic overview finds variation in approaches to investigating and reporting on sources of heterogeneity in systematic reviews of diagnostic studies

    NARCIS (Netherlands)

    Naaktgeboren, Christiana A.; van Enst, Wynanda A.; Ochodo, Eleanor A.; de Groot, Joris A. H.; Hooft, Lotty; Leeflang, Mariska M.; Bossuyt, Patrick M.; Moons, Karel G. M.; Reitsma, Johannes B.

    2014-01-01

    To examine how authors explore and report on sources of heterogeneity in systematic reviews of diagnostic accuracy studies. A cohort of systematic reviews of diagnostic tests was systematically identified. Data were extracted on whether an exploration of the sources of heterogeneity was undertaken,

  2. EU-US transport task force workshop on transport in fusion plasmas: transport near operational limits

    International Nuclear Information System (INIS)

    Connor, J W; Garbet, X; Giannone, L; Greenwald, M; Hidalgo, C; Loarte, A; Mantica, P

    2003-01-01

    This conference report summarizes the contributions to, and discussions at, the 9th EU-US transport task force workshop on 'transport in fusion plasmas: transport near operational limits', held in Cordoba, Spain, during 9-12 September 2002. The workshop was organized under three main headings: edge localized mode physics and confinement, profile dynamics and confinement and confinement near operational limits: density and beta limits; this report follows the same structure

  3. Transportation Business Plan

    International Nuclear Information System (INIS)

    1986-01-01

    The Transportation Business Plan is a step in the process of procuring the transportation system. It sets the context for business strategy decisions by providing pertinent background information, describing the legislation and policies governing transportation under the NWPA, and describing requirements of the transportation system. Included in the document are strategies for procuring shipping casks and transportation support services. In the spirit of the NWPA directive to utilize the private sector to the maximum extent possible, opportunities for business ventures are obvious throughout the system development cycle

  4. Electronic and magnetic phase separation in EuB{sub 6}. Fluctuation spectroscopy and nonlinear transport; Elektronische und magnetische Phasenseparation in EuB{sub 6}. Fluktuationsspektroskopie und nichtlinearer Transport

    Energy Technology Data Exchange (ETDEWEB)

    Amyan, Adham

    2013-07-09

    The main topics of this thesis are electrical, stationary, and time-resolved transport measurements on EuB{sub 6} as well as the further development of measuring methods and analysis procedures of the fluctuation spectroscopy. The first part of this thesis was dedicated to the further development of the already known measuring methods under application of a fast data-acquisition card. The second part deals with the electrical transport properties of EuB{sub 6} and the understanding of the coupling between charge and magnetic degrees of freedom. By means of resistance and nonlinear-transport measurements as well as fluctuation spectroscopy hypotheses of other scientists were systematically verified as well as new knowledge obtained. The magnetoresistance was studied as function of the temperature in small external magnetic fields between 1 mT and 700 mT. Measurements of the third harmonic resistance as function of the temperature show maxima at T{sub MI} and T{sub C}. Electrical-resistance fluctuations were measured without external magnetic field between 5 and 100 K as well in presence of a magnetic field between 18 K and 32 K. At constant temperature measurements of the spectral power density in external magnetic fields were performed in the temperature range from 18 K to 32 K. Highly resolving measurements of the thermal expansion coefficient showed a very strong coupling of the magnetic (polaronic) degrees of freedom to the crystal lattice.

  5. Transport of radioactive substances

    International Nuclear Information System (INIS)

    2014-12-01

    The report on the transport of radioactive substances covers the following topics: facts on radioactive materials transport, safety of the transport of radioactive substances, legal regulations and guidelines: a multiform but consistent system, transport of nuclear fuels, safety during the transport of nuclear fuel, future transport of spent fuel elements and high-level radioactive wastes in Germany.

  6. Pre-slaughter cattle welfare indicators for use in commercial abattoirs with voluntary monitoring systems: A systematic review.

    Science.gov (United States)

    Losada-Espinosa, Natyieli; Villarroel, Morris; María, Gustavo A; Miranda-de la Lama, Genaro C

    2018-04-01

    Animal welfare has become an important subject of public, economic and political concern, leading to the need to validate indicators that are feasible to use at abattoirs. A systematic review was carried out, which identified 72 cattle welfare indicators (CWI) that were classified into four categories (physiological, morphometric, behavioral and meat quality). Their validity and feasibility for use in abattoirs were evaluated as potential measures of cattle welfare during transportation to the abattoir and at the abattoir itself. Several highly valid indicators were identified that are useful to assess welfare at abattoirs, including body condition score, human-animal interactions, vocalizations, falling, carcass bruising, and meat pH. In addition, some intermediate valid indicators are useful and should be investigated further. Information along the food chain could be used systematically to provide a basis for a more-risk-based meat inspection. An integrated system based on the use of key indicators defined for each inspection step with the setting of alarm thresholds could be implemented. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Nanoscale thermal transport. II. 2003–2012

    International Nuclear Information System (INIS)

    Cahill, David G.; Braun, Paul V.; Chen, Gang; Clarke, David R.; Fan, Shanhui; Goodson, Kenneth E.; Keblinski, Pawel; King, William P.; Mahan, Gerald D.; Majumdar, Arun; Maris, Humphrey J.; Phillpot, Simon R.; Pop, Eric; Shi, Li

    2014-01-01

    A diverse spectrum of technology drivers such as improved thermal barriers, higher efficiency thermoelectric energy conversion, phase-change memory, heat-assisted magnetic recording, thermal management of nanoscale electronics, and nanoparticles for thermal medical therapies are motivating studies of the applied physics of thermal transport at the nanoscale. This review emphasizes developments in experiment, theory, and computation in the past ten years and summarizes the present status of the field. Interfaces become increasingly important on small length scales. Research during the past decade has extended studies of interfaces between simple metals and inorganic crystals to interfaces with molecular materials and liquids with systematic control of interface chemistry and physics. At separations on the order of ∼1 nm, the science of radiative transport through nanoscale gaps overlaps with thermal conduction by the coupling of electronic and vibrational excitations across weakly bonded or rough interfaces between materials. Major advances in the physics of phonons include first principles calculation of the phonon lifetimes of simple crystals and application of the predicted scattering rates in parameter-free calculations of the thermal conductivity. Progress in the control of thermal transport at the nanoscale is critical to continued advances in the density of information that can be stored in phase change memory devices and new generations of magnetic storage that will use highly localized heat sources to reduce the coercivity of magnetic media. Ultralow thermal conductivity—thermal conductivity below the conventionally predicted minimum thermal conductivity—has been observed in nanolaminates and disordered crystals with strong anisotropy. Advances in metrology by time-domain thermoreflectance have made measurements of the thermal conductivity of a thin layer with micron-scale spatial resolution relatively routine. Scanning thermal microscopy and

  8. Post-Golgi anterograde transport requires GARP-dependent endosome-to-TGN retrograde transport

    Science.gov (United States)

    Hirata, Tetsuya; Fujita, Morihisa; Nakamura, Shota; Gotoh, Kazuyoshi; Motooka, Daisuke; Murakami, Yoshiko; Maeda, Yusuke; Kinoshita, Taroh

    2015-01-01

    The importance of endosome-to–trans-Golgi network (TGN) retrograde transport in the anterograde transport of proteins is unclear. In this study, genome-wide screening of the factors necessary for efficient anterograde protein transport in human haploid cells identified subunits of the Golgi-associated retrograde protein (GARP) complex, a tethering factor involved in endosome-to-TGN transport. Knockout (KO) of each of the four GARP subunits, VPS51–VPS54, in HEK293 cells caused severely defective anterograde transport of both glycosylphosphatidylinositol (GPI)-anchored and transmembrane proteins from the TGN. Overexpression of VAMP4, v-SNARE, in VPS54-KO cells partially restored not only endosome-to-TGN retrograde transport, but also anterograde transport of both GPI-anchored and transmembrane proteins. Further screening for genes whose overexpression normalized the VPS54-KO phenotype identified TMEM87A, encoding an uncharacterized Golgi-resident membrane protein. Overexpression of TMEM87A or its close homologue TMEM87B in VPS54-KO cells partially restored endosome-to-TGN retrograde transport and anterograde transport. Therefore GARP- and VAMP4-dependent endosome-to-TGN retrograde transport is required for recycling of molecules critical for efficient post-Golgi anterograde transport of cell-surface integral membrane proteins. In addition, TMEM87A and TMEM87B are involved in endosome-to-TGN retrograde transport. PMID:26157166

  9. 13th EU-US Transport Task Force Workshop on transport in fusion plasmas

    DEFF Research Database (Denmark)

    Connor, J.W.; Fasoli, A.; Hidalgo, C.

    2009-01-01

    This report summarizes the contributions presented at the 13th EU-US Transport Task Force Workshop on transport in fusion plasmas, held in Copenhagen, Denmark, 1-4 September 2008. There were sessions on core heat and particle transport; core and edge momentum transport; edge and scrape-off-layer ......This report summarizes the contributions presented at the 13th EU-US Transport Task Force Workshop on transport in fusion plasmas, held in Copenhagen, Denmark, 1-4 September 2008. There were sessions on core heat and particle transport; core and edge momentum transport; edge and scrape...

  10. Compaction parameters and technologies in forest- and long- distance transportation of wood fuels; Tiivistaemisparametrit ja -tekniikat puupolttoaineiden metsae- ja kaukokuljetuksessa

    Energy Technology Data Exchange (ETDEWEB)

    Kaipainen, H [VTT Energy, Jyvaeskylae (Finland)

    1997-12-01

    The objective of the research is to increase the level of knowledge by the aid of systematic research on the timber and the compacting of the fragments of it for forest and lorry transportation. Theoretical information on the compacting phenomena, and the factors effecting on them, will be composed in the study, and the compacting techniques with different raw materials will be studied experimentally. The objective is to reduce the forest transportation costs by 10 % and those of lorry transportation by 15 - 20 % depending on the raw material to be transported. The data obtained in the researches carried out both in Finland and abroad will be investigated in the project. The data consists also of the baling and bundling of felling residues and small-diameter wood. A test equipment, by which the compacting parameters of first thinning pine and spruce felling residues will be determined under winter conditions, was constructed to serve the experimental part of the research. The compacting tests were started at the end of January 1997, so the results of the tests will be available for the final report of 1997 in March 1997. (orig.)

  11. 17 CFR 230.426 - Filing of certain prospectuses under § 230.167 in connection with certain offerings of asset...

    Science.gov (United States)

    2010-04-01

    ... intention to purchase the asset-backed securities. (2) Any ABS informational and computational material if a... issuer or an underwriter that it will purchase all or a portion of the class of asset-backed securities...

  12. Up-gradient transport in a probabilistic transport model

    DEFF Research Database (Denmark)

    Gavnholt, J.; Juul Rasmussen, J.; Garcia, O.E.

    2005-01-01

    The transport of particles or heat against the driving gradient is studied by employing a probabilistic transport model with a characteristic particle step length that depends on the local concentration or heat gradient. When this gradient is larger than a prescribed critical value, the standard....... These results supplement recent works by van Milligen [Phys. Plasmas 11, 3787 (2004)], which applied Levy distributed step sizes in the case of supercritical gradients to obtain the up-gradient transport. (c) 2005 American Institute of Physics....

  13. UFD Storage and Transportation - Transportation Working Group Report

    International Nuclear Information System (INIS)

    Maheras, Steven J.; Ross, Steven B.

    2011-01-01

    The Used Fuel Disposition (UFD) Transportation Task commenced in October 2010. As its first task, Pacific Northwest National Laboratory (PNNL) compiled a list of structures, systems, and components (SSCs) of transportation systems and their possible degradation mechanisms during extended storage. The list of SSCs and the associated degradation mechanisms (known as features, events, and processes (FEPs)) were based on the list of used nuclear fuel (UNF) storage system SSCs and degradation mechanisms developed by the UFD Storage Task (Hanson et al. 2011). Other sources of information surveyed to develop the list of SSCs and their degradation mechanisms included references such as Evaluation of the Technical Basis for Extended Dry Storage and Transportation of Used Nuclear Fuel (NWTRB 2010), Transportation, Aging and Disposal Canister System Performance Specification, Revision 1 (OCRWM 2008), Data Needs for Long-Term Storage of LWR Fuel (EPRI 1998), Technical Bases for Extended Dry Storage of Spent Nuclear Fuel (EPRI 2002), Used Fuel and High-Level Radioactive Waste Extended Storage Collaboration Program (EPRI 2010a), Industry Spent Fuel Storage Handbook (EPRI 2010b), and Transportation of Commercial Spent Nuclear Fuel, Issues Resolution (EPRI 2010c). SSCs include items such as the fuel, cladding, fuel baskets, neutron poisons, metal canisters, etc. Potential degradation mechanisms (FEPs) included mechanical, thermal, radiation and chemical stressors, such as fuel fragmentation, embrittlement of cladding by hydrogen, oxidation of cladding, metal fatigue, corrosion, etc. These degradation mechanisms are discussed in Section 2 of this report. The degradation mechanisms have been evaluated to determine if they would be influenced by extended storage or high burnup, the need for additional data, and their importance to transportation. These categories were used to identify the most significant transportation degradation mechanisms. As expected, for the most part, the

  14. Transportation Satellite Accounts : A New Way of Measuring Transportation Services in America

    Science.gov (United States)

    2011-01-01

    Transportation Satellite Accounts (TSA), produced by the Bureau of Economic Analysis and the Bureau of Transportation Statistics, provides measures of national transportation output. TSA includes both in-house and for-hire transportation services. Fo...

  15. Simulations of Electron Transport in Laser Hot Spots

    International Nuclear Information System (INIS)

    Brunner, S.; Valeo, E.

    2001-01-01

    Simulations of electron transport are carried out by solving the Fokker-Planck equation in the diffusive approximation. The system of a single laser hot spot, with open boundary conditions, is systematically studied by performing a scan over a wide range of the two relevant parameters: (1) Ratio of the stopping length over the width of the hot spot. (2) Relative importance of the heating through inverse Bremsstrahlung compared to the thermalization through self-collisions. As for uniform illumination [J.P. Matte et al., Plasma Phys. Controlled Fusion 30 (1988) 1665], the bulk of the velocity distribution functions (VDFs) present a super-Gaussian dependence. However, as a result of spatial transport, the tails are observed to be well represented by a Maxwellian. A similar dependence of the distributions is also found for multiple hot spot systems. For its relevance with respect to stimulated Raman scattering, the linear Landau damping of the electron plasma wave is estimated for such VD Fs. Finally, the nonlinear Fokker-Planck simulations of the single laser hot spot system are also compared to the results obtained with the linear non-local hydrodynamic approach [A.V. Brantov et al., Phys. Plasmas 5 (1998) 2742], thus providing a quantitative limit to the latter method: The hydrodynamic approach presents more than 10% inaccuracy in the presence of temperature variations of the order delta T/T greater than or equal to 1%, and similar levels of deformation of the Gaussian shape of the Maxwellian background

  16. Using systematic review in occupational safety and health.

    Science.gov (United States)

    Howard, John; Piacentino, John; MacMahon, Kathleen; Schulte, Paul

    2017-11-01

    Evaluation of scientific evidence is critical in developing recommendations to reduce risk. Healthcare was the first scientific field to employ a systematic review approach for synthesizing research findings to support evidence-based decision-making and it is still the largest producer and consumer of systematic reviews. Systematic reviews in the field of occupational safety and health are being conducted, but more widespread use and adoption would strengthen assessments. In 2016, NIOSH asked RAND to develop a framework for applying the traditional systematic review elements to the field of occupational safety and health. This paper describes how essential systematic review elements can be adapted for use in occupational systematic reviews to enhance their scientific quality, objectivity, transparency, reliability, utility, and acceptability. Published 2017. This article is a U.S. Government work and is in the public domain in the USA.

  17. Transportation safety training

    International Nuclear Information System (INIS)

    Jones, E.

    1990-01-01

    Over the past 25 years extensive federal legislation involving the handling and transport of hazardous materials/waste has been passed that has resulted in numerous overlapping regulations administered and enforced by different federal agencies. The handling and transport of hazardous materials/waste involves a significant number of workers who are subject to a varying degree of risk should an accident occur during handling or transport. Effective transportation training can help workers address these risks and mitigate them, and at the same time enable ORNL to comply with the federal regulations concerning the transport of hazardous materials/waste. This presentation will outline how the Environmental and Health Protection Division's Technical Resources and Training Section at the Oak Ridge National Laboratory, working with transportation and waste disposal personnel, have developed and implemented a comprehensive transportation safety training program to meet the needs of our workers while satisfying appropriate federal regulations. 8 refs., 3 tabs

  18. TRANSPORT/HANDLING REQUESTS

    CERN Multimedia

    Groupe ST/HM

    2002-01-01

    A new EDH document entitled 'Transport/Handling Request' will be in operation as of Monday, 11th February 2002, when the corresponding icon will be accessible from the EDH desktop, together with the application instructions. This EDH form will replace the paper-format transport/handling request form for all activities involving the transport of equipment and materials. However, the paper form will still be used for all vehicle-hire requests. The introduction of the EDH transport/handling request form is accompanied by the establishment of the following time limits for the various services concerned: 24 hours for the removal of office items, 48 hours for the transport of heavy items (of up to 6 metric tons and of standard road width), 5 working days for a crane operation, extra-heavy transport operation or complete removal, 5 working days for all transport operations relating to LHC installation. ST/HM Group, Logistics Section Tel: 72672 - 72202

  19. Systematics of the level density parameters

    International Nuclear Information System (INIS)

    Ignatyuk, A.V.; Istekov, K.K.; Smirenkin, G.N.

    1977-01-01

    The excitation energy dependence of nucleus energy-level density is phenomenologically systematized in terms of the Fermi gas model. The analysis has been conducted in the atomic mass number range of A(>=)150, where the collective effects are mostly pronounced. The density parameter a(U) is obtained using data on neutron resonances. To depict energy spectra of nuclear states in the Fermi gas model (1) the contributions from collective rotational and vibrational modes (2), as well as from pair correlations (3) are also taken into account. It is shown, that at excitation energies close to the neutron binding energy all three systematics of a(U) yield practically the same energy-level densities. At high energies only the (2) and (3) systematics are valid, and at energies lower than the neutron binding energy only the last systematics will be adequate

  20. Transport in Halobacterium Halobium: Light-Induced Cation-Gradients, Amino Acid Transport Kinetics, and Properties of Transport Carriers

    Science.gov (United States)

    Lanyi, Janos K.

    1977-01-01

    Cell envelope vesicles prepared from H. halobium contain bacteriorhodopsin and upon illumination protons are ejected. Coupled to the proton motive force is the efflux of Na(+). Measurements of Na-22 flux, exterior pH change, and membrane potential, Delta(psi) (with the dye 3,3'-dipentyloxadicarbocyanine) indicate that the means of Na(+) transport is sodium/proton exchange. The kinetics of the pH changes and other evidence suggests that the antiport is electrogenic (H(+)/Na(++ greater than 1). The resulting large chemical gradient for Na(+) (outside much greater than inside), as well as the membrane potential, will drive the transport of 18 amino acids. The I9th, glutamate, is unique in that its accumulation is indifferent to Delta(psi): this amino acid is transported only when a chemical gradient for Na(+) is present. Thus, when more and more NaCl is included in the vesicles glutamate transport proceeds with longer and longer lags. After illumination the gradient of H+() collapses within 1 min, while the large Na(+) gradient and glutamate transporting activity persists for 10- 15 min, indicating that proton motive force is not necessary for transport. A chemical gradient of Na(+), arranged by suspending vesicles loaded with KCl in NaCl, drives glutamate transport in the dark without other sources of energy, with V(sub max) and K(sub m) comparable to light-induced transport. These and other lines of evidence suggest that the transport of glutamate is facilitated by symport with Na(+), in an electrically neutral fashion, so that only the chemical component of the Na(+) gradient is a driving force.