WorldWideScience

Sample records for transportation federal motor

  1. 49 CFR 397.2 - Compliance with Federal motor carrier safety regulations.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Compliance with Federal motor carrier safety...) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS TRANSPORTATION OF HAZARDOUS MATERIALS; DRIVING AND PARKING RULES General § 397.2 Compliance with...

  2. Forecasting of Energy and Petroleum Consumption by Motor Transport in the Regions of the Russian Federation

    Directory of Open Access Journals (Sweden)

    Leontiy Viktorovich Eder

    2017-09-01

    Full Text Available The paper offers the directions for the improvement of methodological approach to forecasting the energy consumption in transport, taking into account special features of Russian regions. The authors developed a multivariate model allowing to predict the motor vehicle rate specified for the regions of the Russian Federation depending on the economic, social and institutional features. We formalized the dynamic (trend model for predicting the effectiveness of energy consumption per unit of the vehicle in Russia with details on Federal districts. In the study, in predicting the number of motor transport, the authors applied the methods of economic and mathematical simulation modelling based on the results of the econometric analysis for the calculation of the population having motor transport. In determining the potential specific energy consumption, we have aggregated trending patterns and convergence. The study has shown that by 2040, the number of passenger cars in Russia will grow to 57.1 million, and the total number of all types of road transport will grow by 14.9 million units to 66.2 million. The highest growth rates are predicted in the Central regions of Russia and in some areas of Siberia. The smallest growth rates are expected in the Chukotka Autonomous District, Kamchatka and Primorsky regions. Energy efficiency in transport and active introduction of alternative motor fuels, primarily methane, will reduce the consumption of gasoline and diesel fuel by motor transport. Thus, in the forecast period of 2018–2040, the consumption of petroleum products by motor transport will be reduced by 8.9 million tons: from 61,9 million tons of oil to 51.7 million tons of oil. The results of the study can be applied for the formulation of proposals on the creation of scientific and methodological apparatus to predict the development of transport sector and oil products supply in of the regions of Russia.

  3. 77 FR 54836 - Federal Motor Vehicle Safety Standards

    Science.gov (United States)

    2012-09-06

    ... DEPARTMENT OF TRANSPORTATION National Highway Traffic Safety Administration 49 CFR Part 571 Federal Motor Vehicle Safety Standards CFR Correction 0 In Title 49 of the Code of Federal Regulations... read as follows: Sec. 571.119 Standard No. 119; New pneumatic tires for motor vehicles with a GVWR of...

  4. 77 FR 65765 - Petition for Exemption From the Federal Motor Vehicle Motor Theft Prevention Standard; General...

    Science.gov (United States)

    2012-10-30

    ... the vehicle. The antenna module translates the radio frequency signal received from the key into a... DEPARTMENT OF TRANSPORTATION National Highway Traffic Safety Administration Petition for Exemption From the Federal Motor Vehicle Motor Theft Prevention Standard; General Motors Corporation AGENCY...

  5. 77 FR 25534 - Petition for Exemption From the Federal Motor Vehicle Motor Theft Prevention Standard; General...

    Science.gov (United States)

    2012-04-30

    ... response back to the vehicle. The antenna module translates the radio frequency signal received from the... DEPARTMENT OF TRANSPORTATION National Highway Traffic Safety Administration Petition for Exemption From the Federal Motor Vehicle Motor Theft Prevention Standard; General Motors Corporation AGENCY...

  6. 78 FR 77790 - Petition for Exemption From the Federal Motor Vehicle Theft Prevention Standard; General Motors...

    Science.gov (United States)

    2013-12-24

    ... vehicle. The antenna module translates the radio frequency signal received from the key into a digital... DEPARTMENT OF TRANSPORTATION National Highway Traffic Safety Administration Petition for Exemption From the Federal Motor Vehicle Theft Prevention Standard; General Motors Corporation AGENCY: National...

  7. 78 FR 4193 - Petition for Exemption From the Federal Motor Vehicle Motor Theft Prevention Standard; Volvo

    Science.gov (United States)

    2013-01-18

    ... DEPARTMENT OF TRANSPORTATION National Highway Traffic Safety Administration Petition for Exemption From the Federal Motor Vehicle Motor Theft Prevention Standard; Volvo AGENCY: National Highway Traffic... transponder is not identified, the CEM will not send an approved key signal to the IAU and the vehicle will be...

  8. 77 FR 20558 - Federal Motor Vehicle Safety Standards; Platform Lifts for Motor Vehicles; Platform Lift...

    Science.gov (United States)

    2012-04-05

    ... unrelated to the barrier's safety. Lift-U also questioned the agency's statement that it could be difficult... DEPARTMENT OF TRANSPORTATION National Highway Traffic Safety Administration 49 CFR Part 571 [Docket No. NHTSA-2012-0039] RIN 2127-AJ93 Federal Motor Vehicle Safety Standards; Platform Lifts for...

  9. 19 CFR 12.80 - Federal motor vehicle safety standards.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Federal motor vehicle safety standards. 12.80...; DEPARTMENT OF THE TREASURY SPECIAL CLASSES OF MERCHANDISE Motor Vehicles and Motor Vehicle Equipment Manufactured on Or After January 1, 1968 § 12.80 Federal motor vehicle safety standards. (a) Standards...

  10. 77 FR 22383 - Petition for Exemption From the Federal Motor Vehicle Motor Theft Prevention Standard; TESLA

    Science.gov (United States)

    2012-04-13

    ... From the Federal Motor Vehicle Motor Theft Prevention Standard; TESLA AGENCY: National Highway Traffic... exemption. SUMMARY: This document grants in full the petition of Tesla Motors Inc's. (Tesla) for an... 49 CFR Part 541, Federal Motor Vehicle Theft Prevention Standard. Tesla requested confidential...

  11. 49 CFR 383.91 - Commercial motor vehicle groups.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Commercial motor vehicle groups. 383.91 Section 383.91 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS COMMERCIAL...

  12. 49 CFR 397.67 - Motor carrier responsibility for routing.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Motor carrier responsibility for routing. 397.67 Section 397.67 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS...

  13. 49 CFR 373.101 - Motor carrier bills of lading.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Motor carrier bills of lading. 373.101 Section 373.101 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS RECEIPTS AND...

  14. 76 FR 76622 - Federal Management Regulation; Motor Vehicle Management

    Science.gov (United States)

    2011-12-08

    ...; Docket 2011-0011; Sequence 2] RIN 3090-AJ14 Federal Management Regulation; Motor Vehicle Management... Administration is amending the Federal Management Regulation (FMR) by revising current policy on the definitions... CONTACT: For clarification of content, contact Mr. James Vogelsinger, Director, Motor Vehicle Management...

  15. 76 FR 55825 - Federal Motor Vehicle Safety Standards, Child Restraint Systems

    Science.gov (United States)

    2011-09-09

    ... [Docket No. NHTSA-2011-0139] RIN 2127-AJ44 Federal Motor Vehicle Safety Standards, Child Restraint Systems..., amends a provision in Federal Motor Vehicle Safety Standard No. 213, ``Child restraint systems,'' that... provision: When a motor vehicle safety standard is in effect under this chapter, a State or a political...

  16. 75 FR 22317 - Federal Motor Vehicle Safety Standards; Small Business Impacts of Motor Vehicle Safety

    Science.gov (United States)

    2010-04-28

    ... 1300 [Docket No. NHTSA-2010-0054] Federal Motor Vehicle Safety Standards; Small Business Impacts of Motor Vehicle Safety AGENCY: National Highway Traffic Safety Administration (NHTSA), Department of..., multipurpose passenger vehicles, trucks, buses, trailers, incomplete vehicles, motorcycles, and motor vehicle...

  17. 49 CFR 385.303 - How does a motor carrier register with the FMCSA?

    Science.gov (United States)

    2010-10-01

    ... Washington, DC headquarters by mail at, Federal Motor Carrier Safety Administration, 1200 New Jersey Ave., SE... 49 Transportation 5 2010-10-01 2010-10-01 false How does a motor carrier register with the FMCSA...) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY...

  18. 76 FR 12792 - Petition for Exemption From the Federal Motor Vehicle Motor Theft Prevention Standard; General...

    Science.gov (United States)

    2011-03-08

    ... From the Federal Motor Vehicle Motor Theft Prevention Standard; General Motors Corporation AGENCY..., Exemption from the Theft Prevention Standard. This petition is granted because the agency has determined... in reducing and deterring motor vehicle theft as compliance with the parts-marking requirements of...

  19. 49 CFR 229.91 - Motors and generators.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Motors and generators. 229.91 Section 229.91 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION....91 Motors and generators. A motor or a generator may not have any of the following conditions: (a) Be...

  20. 75 FR 15620 - Federal Motor Vehicle Safety Standards; Air Brake Systems

    Science.gov (United States)

    2010-03-30

    ... fully develop improved brake systems and also to ensure vehicle control and stability while braking... [Docket No. NHTSA 2009-0175] RIN 2127-AK62 Federal Motor Vehicle Safety Standards; Air Brake Systems... Federal motor vehicle safety standard for air brake systems by requiring substantial improvements in...

  1. 78 FR 9623 - Federal Motor Vehicle Safety Standards; Air Brake Systems

    Science.gov (United States)

    2013-02-11

    ... initial speeds, vehicle manufacturers will need to develop unique or complicated braking systems to comply... [Docket No. NHTSA-2013-0011] RIN 2127-AL11 Federal Motor Vehicle Safety Standards; Air Brake Systems... rule that amended the Federal motor vehicle safety standard for air brake systems by requiring...

  2. 76 FR 44829 - Federal Motor Vehicle Safety Standards; Air Brake Systems

    Science.gov (United States)

    2011-07-27

    ... [Docket No. NHTSA-2009-0175] RIN 2127-AK84 Federal Motor Vehicle Safety Standards; Air Brake Systems... final rule that amended the Federal motor vehicle safety standard for air brake systems by requiring... between Bendix Commercial Vehicle Systems and Dana Corporation; and ArvinMeritor. The agency received four...

  3. 78 FR 66801 - Motor Carrier Safety Advisory Committee; Charter Renewal

    Science.gov (United States)

    2013-11-06

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2006-26367] Motor Carrier Safety Advisory Committee; Charter Renewal AGENCY: Federal Motor Carrier Safety... and recommendations on motor carrier safety programs and motor carrier safety regulations through a...

  4. 78 FR 3081 - Petition for Exemption From the Federal Motor Vehicle Motor Theft Prevention Standard; Toyota

    Science.gov (United States)

    2013-01-15

    ... From the Federal Motor Vehicle Motor Theft Prevention Standard; Toyota AGENCY: National Highway Traffic.... SUMMARY: This document grants in full Toyota Motor North America, Inc.'s (Toyota) petition for an... a petition dated October 16, 2012, Toyota requested an exemption from the parts-marking requirements...

  5. 76 FR 12221 - Petition for Exemption From the Federal Motor Vehicle Motor Theft Prevention Standard; Toyota

    Science.gov (United States)

    2011-03-04

    ... From the Federal Motor Vehicle Motor Theft Prevention Standard; Toyota AGENCY: National Highway Traffic.... SUMMARY: This document grants in full the petition of Toyota Motor North America, Inc's., (Toyota... INFORMATION: In a petition dated January 24, 2011, Toyota requested an exemption from the parts-marking...

  6. 77 FR 29752 - Petition for Exemption From the Federal Motor Vehicle Motor Theft Prevention Standard; Jaguar...

    Science.gov (United States)

    2012-05-18

    ... From the Federal Motor Vehicle Motor Theft Prevention Standard; Jaguar Land Rover AGENCY: National... part 543, Exemption from the Theft Prevention Standard. This petition is granted, because the agency... be as effective in reducing and deterring motor vehicle theft as compliance with the parts-marking...

  7. 76 FR 12220 - Petition for Exemption From the Federal Motor Vehicle Motor Theft Prevention Standard; Jaguar...

    Science.gov (United States)

    2011-03-04

    ... From the Federal Motor Vehicle Motor Theft Prevention Standard; Jaguar Land Rover AGENCY: National... 543, Exemption from the Theft Prevention Standard. This petition is granted because the agency has... effective in reducing and deterring motor vehicle theft as compliance with the parts-marking requirements of...

  8. 76 FR 23255 - Federal Motor Vehicle Safety Standards; Lamps, Reflective Devices, and Associated Equipment

    Science.gov (United States)

    2011-04-26

    ... petitions for reconsideration from Harley-Davidson Motor Company (January 18, 2008) and Ford Motor Company... [Docket No. NHTSA-2007-28322] Federal Motor Vehicle Safety Standards; Lamps, Reflective Devices, and... part, the petitions for reconsideration of the December 4, 2007, final rule reorganizing Federal Motor...

  9. 77 FR 4396 - Petition for Exemption From the Federal Motor Vehicle Motor Theft Prevention Standard; Toyota

    Science.gov (United States)

    2012-01-27

    ... From the Federal Motor Vehicle Motor Theft Prevention Standard; Toyota AGENCY: National Highway Traffic... exemption. SUMMARY: This document grants in full the petition of Toyota Motor North America, Inc's., (Toyota.... SUPPLEMENTARY INFORMATION: In a petition dated September 30, 2011, Toyota requested an exemption from the parts...

  10. 76 FR 32390 - Motor Carrier Safety Advisory Committee Public Meeting

    Science.gov (United States)

    2011-06-06

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2006-26367] Motor Carrier Safety Advisory Committee Public Meeting AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of Motor Carrier Safety Advisory Committee (MCSAC) Meeting. SUMMARY...

  11. 77 FR 46555 - Motor Carrier Safety Advisory Committee: Public Meeting

    Science.gov (United States)

    2012-08-03

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2006-26367] Motor Carrier Safety Advisory Committee: Public Meeting AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of meeting of Motor Carrier Safety Advisory Committee (MCSAC...

  12. 75 FR 2923 - Motor Carrier Safety Advisory Committee Public Meeting

    Science.gov (United States)

    2010-01-19

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2006-26367] Motor Carrier Safety Advisory Committee Public Meeting AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of Motor Carrier Safety Advisory Committee Meeting. SUMMARY: FMCSA...

  13. 75 FR 29384 - Motor Carrier Safety Advisory Committee Public Meeting

    Science.gov (United States)

    2010-05-25

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2010-0143] Motor Carrier Safety Advisory Committee Public Meeting AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of Motor Carrier Safety Advisory Committee meeting. SUMMARY: FMCSA...

  14. 75 FR 72863 - Motor Carrier Safety Advisory Committee Public Meeting

    Science.gov (United States)

    2010-11-26

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2006-26367] Motor Carrier Safety Advisory Committee Public Meeting AGENCY: Federal Motor Carrier Safety Administration, DOT. ACTION: Notice of Motor Carrier Safety Advisory Committee Meeting. SUMMARY: FMCSA announces...

  15. 75 FR 50797 - Motor Carrier Safety Advisory Committee Public Meeting

    Science.gov (United States)

    2010-08-17

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2010-0143] Motor Carrier Safety Advisory Committee Public Meeting AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of Motor Carrier Safety Advisory Committee Meeting. SUMMARY: FMCSA...

  16. 75 FR 76692 - Federal Motor Vehicle Safety Standards; Small Business Impacts of Motor Vehicle Safety

    Science.gov (United States)

    2010-12-09

    ..., 510, 511, 512, 520, 523, 525, 526, and 571 [Docket No. NHTSA-2010-0159] Federal Motor Vehicle Safety Standards; Small Business Impacts of Motor Vehicle Safety AGENCY: National Highway Traffic Safety... that specifically relate to passenger cars, multipurpose passenger vehicles, trucks, buses, trailers...

  17. 76 FR 24402 - Federal Motor Vehicle Theft Prevention Standard

    Science.gov (United States)

    2011-05-02

    ... [Docket No. NHTSA-2009-0069] RIN 2127-AK81 Federal Motor Vehicle Theft Prevention Standard AGENCY... address for submission, and the procedure to submit designation of target areas on high theft major parts... the Theft Prevention Standard, manufacturers of high theft passenger motor vehicle lines subject to...

  18. Review of the Federal Motor Carrier Safety Regulations for Automated Commercial Vehicles: Preliminary Assessment of Interpretation and Enforcement Challenges, Questions, and Gaps

    Science.gov (United States)

    2018-03-01

    The Volpe National Transportation Systems Center (Volpe) reviewed the Federal Motor Carrier Safety Regulations (FMCSRs) to identify compliance and enforcement challenges related to the operation of automated commercial vehicles (CMVs) in interstate c...

  19. 49 CFR 541.5 - Requirements for passenger motor vehicles.

    Science.gov (United States)

    2010-10-01

    ... TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR VEHICLE THEFT PREVENTION STANDARD § 541.5 Requirements for passenger motor vehicles. (a) Each passenger motor vehicle subject to... 49 Transportation 6 2010-10-01 2010-10-01 false Requirements for passenger motor vehicles. 541.5...

  20. 76 FR 31545 - Federal Management Regulation; Motor Vehicle Management

    Science.gov (United States)

    2011-06-01

    ...; Sequence 1] RIN 3090-AJ14 Federal Management Regulation; Motor Vehicle Management AGENCY: Office of... Services Administration is proposing to amend the Federal Management Regulation (FMR) by revising current....C. 553(a)(2) because it applies to agency management. However, this proposed rule is being published...

  1. 76 FR 5424 - Motor Carrier Safety Advisory Committee; Request for Nominations

    Science.gov (United States)

    2011-01-31

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2006-26367] Motor Carrier Safety Advisory Committee; Request for Nominations AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Request for Nominations to the Motor Carrier Safety Advisory...

  2. Research and technology in the Federal Motor Carrier Safety Administration

    Science.gov (United States)

    2002-01-01

    As the Federal Government's chief commercial vehicle safety agency, the Federal Motor Carrier Safety Administration's (FMCSA), Office of Research and Technology (R&T) focuses on saving lives and reducing injuries by helping to prevent crashes involvi...

  3. METHODS OF DIAGNOSTIC EFFECTIVENESS ORGANIZATIONAL CHANGES IN CARGO MOTOR TRANSPORTATION ORGANIZATIONS

    Directory of Open Access Journals (Sweden)

    Denis Sergeevich Antipov

    2017-03-01

    Full Text Available The article propose methods of diagnostic effectiveness organizational changes in cargo motor transportation organizations. The article contain the main results approbation of the developed methods of diagnostic effectiveness organizational changes in cargo motor transportation organizations in 37 cargo motor transportation organizations of Saint-Petersburg and the Leningrad Region. Constructed diagrams of conformity specific weights resulting from organizational changes in cargo motor transportation organizations. Presents diagrams effectiveness organizational changes in cargo motor transportation organizations at every stages of the life cycle. The goal of the present paper is to development methods of diagnostic effectiveness organizational changes in cargo motor transportation organizations.

  4. 77 FR 15351 - Federal Motor Vehicle Safety Standards; Theft Protection and Rollaway Prevention

    Science.gov (United States)

    2012-03-15

    ... [Docket No. NHTSA-2011-0174] RIN 2127-AK88 Federal Motor Vehicle Safety Standards; Theft Protection and... (NPRM) to amend Federal Motor Vehicle Safety Standard (FMVSS) No. 114, Theft Protection and Rollaway... requesting that certain information, including vehicle owner questionnaires (VOQs) referenced in the NPRM, be...

  5. 75 FR 57191 - Compliance With Interstate Motor Carrier Noise Emission Standards: Exhaust Systems

    Science.gov (United States)

    2010-09-20

    ... 28, 1975, the Federal Highway Administration (FHWA)'s Bureau of Motor Carrier Safety published in the... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration 49 CFR Part 325 [Docket...: Exhaust Systems AGENCY: Federal Motor Carrier Safety Administration, DOT. ACTION: Direct final rule...

  6. 41 CFR 109-38.903-50 - Reporting DOE motor vehicle data.

    Science.gov (United States)

    2010-07-01

    ... AVIATION, TRANSPORTATION, AND MOTOR VEHICLES 38-MOTOR EQUIPMENT MANAGEMENT 38.9-Federal Motor Vehicle Fleet... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Reporting DOE motor vehicle data. 109-38.903-50 Section 109-38.903-50 Public Contracts and Property Management Federal...

  7. 78 FR 5243 - Motor Carrier Safety Advisory Committee (MCSAC): Public Meeting of Subcommittees

    Science.gov (United States)

    2013-01-24

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2006-26367] Motor Carrier Safety Advisory Committee (MCSAC): Public Meeting of Subcommittees AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of meeting of Motor Carrier Safety...

  8. 77 FR 60507 - Motor Carrier Safety Advisory Committee (MCSAC): Public Subcommittee Meeting

    Science.gov (United States)

    2012-10-03

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2006-26367] Motor Carrier Safety Advisory Committee (MCSAC): Public Subcommittee Meeting AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of Meeting of Compliance, Safety...

  9. 78 FR 21850 - Federal Motor Vehicle Safety Standards; Matters Incorporated by Reference

    Science.gov (United States)

    2013-04-12

    ... to the 1985 Annual Book of ASTM Standards, Vol. 05.04, ``Test Methods for Rating Motor, Diesel... for Rating Motor, Diesel, Aviation Fuels, A2. Reference Materials and Blending Accessories, (``ASTM... [Docket No. NHTSA-2011-0185] RIN 2127-AL25 Federal Motor Vehicle Safety Standards; Matters Incorporated by...

  10. 75 FR 6123 - Federal Motor Vehicle Safety Standards; Occupant Crash Protection

    Science.gov (United States)

    2010-02-08

    ... motor vehicle safety standard is in effect under this chapter, a State or a political subdivision of a... [Docket No. NHTSA-2009-0156] RIN 2127-AK57 Federal Motor Vehicle Safety Standards; Occupant Crash...'s response to petitions for reconsideration of a November 12, 2008 final rule that amended the child...

  11. 75 FR 2589 - Petition for Exemption From the Federal Motor Vehicle Theft Prevention Standard; Chrysler

    Science.gov (United States)

    2010-01-15

    ... From the Federal Motor Vehicle Theft Prevention Standard; Chrysler AGENCY: National Highway Traffic... Jeep Patriot vehicle line in accordance with 49 CFR Part 543, Exemption from Vehicle Theft Prevention... vehicle theft as compliance with the parts-marking requirements of 49 CFR Part 541, Federal Motor Vehicle...

  12. 75 FR 53375 - Petition for Exemption From the Federal Motor Vehicle Theft Prevention Standard; Chrysler

    Science.gov (United States)

    2010-08-31

    ... From the Federal Motor Vehicle Theft Prevention Standard; Chrysler AGENCY: National Highway Traffic... the Fiat 500 vehicle line in accordance with 49 CFR Part 543, Exemption From Vehicle Theft Prevention... vehicle theft as compliance with the parts-marking requirements of 49 CFR Part 541, Federal Motor Vehicle...

  13. A simplified tether model for molecular motor transporting cargo

    International Nuclear Information System (INIS)

    Fang-Zhen, Li; Li-Chun, Jiang

    2010-01-01

    Molecular motors are proteins or protein complexes which function as transporting engines in biological cells. This paper models the tether between motor and its cargo as a symmetric linear potential. Different from Elston and Peskin's work for which performance of the system was discussed only in some limiting cases, this study produces analytic solutions of the problem for general cases by simplifying the transport system into two physical states, which makes it possible to discuss the dynamics of the motor–cargo system in detail. It turns out that the tether strength between motor and cargo should be greater than a threshold or the motor will fail to transport the cargo, which was not discussed by former researchers yet. Value of the threshold depends on the diffusion coefficients of cargo and motor and also on the strength of the Brownian ratchets dragging the system. The threshold approaches a finite constant when the strength of the ratchet tends to infinity. (general)

  14. 77 FR 44673 - Meeting of the Department of Justice National Motor Vehicle Title Information System Federal...

    Science.gov (United States)

    2012-07-30

    ... Department of Justice National Motor Vehicle Title Information System Federal Advisory Committee AGENCY... a meeting of Department of Justice's (DOJ's) National Motor Vehicle Title Information System (NMVTIS...., Washington, DC 20531. FOR FURTHER INFORMATION CONTACT: Todd Brighton, Designated Federal Employee (DFE...

  15. Estimating Price Elasticity of Demand for Motor Fuel in the Transport Sectors

    Directory of Open Access Journals (Sweden)

    Olga Vasilyevna Mazurova

    2015-03-01

    Full Text Available Modeling of long-term forecasts of prices and demand on regional energy markets requires accounting for the future changes in the interactions between the greater economy and its energy sector, along with the possible emergence of new factors and specific regional features determining those interactions. The proposed approach allows the study of a correlation between demand and prices for motor fuel, taking into account the competition of energy carriers, the dynamics of energy prices, resource constraints, the use of new technologies and the uncertainty of input data. The main feature of the proposed approach is the combined estimation of the price elasticity of demand for motor fuel with optimization of fuel supply in the region. Thus the author determined elasticity of demand based on the comparison of economic efficiency of the use of different fuels. The study includes results of experimental calculations and forecasted price according to demand for motor fuel in freight transportation for the expected development conditions of the Far Eastern federal district

  16. Economical motor transport operations

    Energy Technology Data Exchange (ETDEWEB)

    Cooke, P

    1979-09-01

    Motor transport is one area in a company where energy conservation is a function primarily of operative education and motivation rather than mechanical or technical control and monitoring. Unless the driver wants to save energy by proper operation of the vehicle, there is nothing the company can do to force him, whatever equipment it fits to the vehicles, or incentives it offers. This article gives an overview of the use of energy in road transport and examines a number of actions that can be taken to conserve energy. It discusses the question of the cost-effectiveness of transport energy conservation in the light of the complex issues involved. The problems and opportunities of implementing energy-saving programs are examined. (MCW)

  17. Motor Carrier Crash Data -

    Data.gov (United States)

    Department of Transportation — Contains data on large trucks and buses involved in Federally reportable crashes as per Title 49 U.S.C. Part 390.5 (crashes involving a commercial motor vehicle, and...

  18. 36 CFR 13.1316 - Commercial transport of passengers by motor vehicles.

    Science.gov (United States)

    2010-07-01

    ... passengers by motor vehicles. 13.1316 Section 13.1316 Parks, Forests, and Public Property NATIONAL PARK... National Park General Provisions § 13.1316 Commercial transport of passengers by motor vehicles. Commercial transport of passengers by motor vehicles on Exit Glacier Road is allowed without a written permit. However...

  19. Robust transport by multiple motors with nonlinear force–velocity relations and stochastic load sharing

    International Nuclear Information System (INIS)

    Kunwar, Ambarish; Mogilner, Alexander

    2010-01-01

    Transport by processive molecular motors plays an important role in many cell biological phenomena. In many cases, motors work together to transport cargos in the cell, so it is important to understand the mechanics of the multiple motors. Based on earlier modeling efforts, here we study effects of nonlinear force–velocity relations and stochastic load sharing on multiple motor transport. We find that when two or three motors transport the cargo, then the nonlinear and stochastic effects compensate so that the mechanical properties of the transport are robust. Similarly, the transport is insensitive to compliance of the cargo-motor links. Furthermore, the rate of movement against moderate loads is not improved by increasing the small number of motors. When the motor number is greater than 4, correlations between the motors become negligible, and the earlier analytical mean-field theory of the multiple motor transport holds. We predict that the effective diffusion of the cargo driven by the multiple motors under load increases by an order of magnitude compared to that for the single motor. Finally, our simulations predict that the stochastic effects are responsible for a significant dispersion of velocities generated by the 'tug-of-war' of the multiple opposing motors

  20. Bidirectional transport of organelles: unity and struggle of opposing motors.

    Science.gov (United States)

    Bryantseva, Sofiya A; Zhapparova, Olga N

    2012-01-01

    Bidirectional transport along microtubules is ensured by opposing motor proteins: cytoplasmic dynein that drives cargo to the minus-ends and various kinesins that generally move to the plus-ends of microtubules. Regulation of motor proteins that are simultaneously bound to the same organelle is required to maintain directional transport and prevent pausing of cargo pulled away by motors of opposite polarity. Debates of the recent decade have been focused on two possible mechanisms of such regulation: (i) coordination, which implies that only one type of motors is active at a given time, and (ii) tug-of-war, which assumes that both motors are active at the same time and that direction of transport depends on the outcome of motor's confrontation. The initial idea of coordination has been challenged by observations of simultaneous activity of plus- and minus-end-directed motors applied to the same cargo. Analysis of the available data indicates that coordination and tug-of-war theories rather complement than contradict each other: cargo interacts with two teams of active motors, the resulting direction and the winner team are determined by coordination complexes, but the activity of the loser team is never completely inhibited and remains at some background level. Such persisting activity might enhance the overall efficiency of transport by increasing processivity or helping to overcome the obstacles on microtubule track. © The Author(s) Journal compilation © 2012 Portland Press Limited

  1. 41 CFR 109-38.204-50 - Records of exempted motor vehicles.

    Science.gov (United States)

    2010-07-01

    ... motor vehicles. 109-38.204-50 Section 109-38.204-50 Public Contracts and Property Management Federal... AVIATION, TRANSPORTATION, AND MOTOR VEHICLES 38-MOTOR EQUIPMENT MANAGEMENT 38.2-Registration, Identification, and Exemptions § 109-38.204-50 Records of exempted motor vehicles. The Director, Office of...

  2. System of business-processes management at motor-transport enterprise

    OpenAIRE

    Коgut, Y.

    2010-01-01

    The place of the system of business-processes management at motor-transport enterprise in the general system of management of the enterprise has been substantiated. The subsystems of strategic management, business-processes management of strategic orientation and current activity, processes of enterprise functioning management have been marked out. The system of motor-transport enterprise business-processes management has been formed, which, unlike the existing ones, is based on the system-cy...

  3. 48 CFR 52.246-14 - Inspection of Transportation.

    Science.gov (United States)

    2010-10-01

    ... Transportation. 52.246-14 Section 52.246-14 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION....246-14 Inspection of Transportation. As prescribed in 46.314, insert the following clause in solicitations and contracts for freight transportation services (including local drayage) by rail, motor...

  4. 77 FR 48105 - Federal Motor Vehicle Safety Standards; Motorcycle Helmets

    Science.gov (United States)

    2012-08-13

    ... [Docket No. NHTSA-2012-0112] Federal Motor Vehicle Safety Standards; Motorcycle Helmets AGENCY: National... Vehicle Safety Standard for motorcycle helmets. Specifically, the final rule amended the helmet labeling... compliance test procedures of FMVSS No. 218, Motorcycle helmets, in order to make it more difficult to...

  5. 75 FR 71648 - Federal Motor Vehicle Safety Standards, Child Restraint Systems; Hybrid III 10-Year-Old Child...

    Science.gov (United States)

    2010-11-24

    ... No. NHTSA-2010-0158 Regulation Identifier No. (RIN) 2127-AJ44 Federal Motor Vehicle Safety Standards, Child Restraint Systems; Hybrid III 10-Year-Old Child Test Dummy AGENCY: National Highway Traffic Safety... (SNPRM). SUMMARY: This document proposes to amend Federal Motor Vehicle Safety Standard (FMVSS) No. 213...

  6. Intracellular transport driven by cytoskeletal motors: General mechanisms and defects

    Science.gov (United States)

    Appert-Rolland, C.; Ebbinghaus, M.; Santen, L.

    2015-09-01

    Cells are the elementary units of living organisms, which are able to carry out many vital functions. These functions rely on active processes on a microscopic scale. Therefore, they are strongly out-of-equilibrium systems, which are driven by continuous energy supply. The tasks that have to be performed in order to maintain the cell alive require transportation of various ingredients, some being small, others being large. Intracellular transport processes are able to induce concentration gradients and to carry objects to specific targets. These processes cannot be carried out only by diffusion, as cells may be crowded, and quite elongated on molecular scales. Therefore active transport has to be organized. The cytoskeleton, which is composed of three types of filaments (microtubules, actin and intermediate filaments), determines the shape of the cell, and plays a role in cell motion. It also serves as a road network for a special kind of vehicles, namely the cytoskeletal motors. These molecules can attach to a cytoskeletal filament, perform directed motion, possibly carrying along some cargo, and then detach. It is a central issue to understand how intracellular transport driven by molecular motors is regulated. The interest for this type of question was enhanced when it was discovered that intracellular transport breakdown is one of the signatures of some neuronal diseases like the Alzheimer. We give a survey of the current knowledge on microtubule based intracellular transport. Our review includes on the one hand an overview of biological facts, obtained from experiments, and on the other hand a presentation of some modeling attempts based on cellular automata. We present some background knowledge on the original and variants of the TASEP (Totally Asymmetric Simple Exclusion Process), before turning to more application oriented models. After addressing microtubule based transport in general, with a focus on in vitro experiments, and on cooperative effects in the

  7. 41 CFR 101-39.203-1 - Obtaining motor vehicles while on temporary duty (TDY) travel.

    Science.gov (United States)

    2010-07-01

    ... Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS AVIATION, TRANSPORTATION, AND MOTOR VEHICLES 39-INTERAGENCY FLEET MANAGEMENT SYSTEMS 39.2-GSA Interagency Fleet Management... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Obtaining motor vehicles...

  8. Dynein is the motor for retrograde axonal transport of organelles

    International Nuclear Information System (INIS)

    Schnapp, B.J.; Reese, T.S.

    1989-01-01

    Vesicular organelles in axons of nerve cells are transported along microtubules either toward their plus ends (fast anterograde transport) or toward their minus ends (retrograde transport). Two microtubule-based motors were previously identified by examining plastic beads induced to move along microtubules by cytosol fractions from the squid giant axon: (i) an anterograde motor, kinesin, and (ii) a retrograde motor, which is characterized here. The retrograde motor, a cytosolic protein previously termed HMW1, was purified from optic lobes and extruded axoplasm by nucleotide-dependent microtubule affinity and release; microtubule gliding was used as the assay of motor activity. The following properties of the retrograde motor suggest that it is cytoplasmic dynein: (i) sedimentation at 20-22 S with a heavy chain of Mr greater than 200,000 that coelectrophoreses with the alpha and beta subunits of axonemal dynein, (ii) cleavage by UV irradiation in the presence of ATP and vanadate, and (iii) a molecular structure resembling two-headed dynein from axonemes. Furthermore, bead movement toward the minus end of microtubules was blocked when axoplasmic supernatants were treated with UV/vanadate. Treatment of axoplasmic supernatant with UV/vanadate also blocks the retrograde movement of purified organelles in vitro without changing the number of anterograde moving organelles, indicating that dynein interacts specifically with a subgroup of organelles programmed to move toward the cell body. However, purified optic lobe dynein, like purified kinesin, does not by itself promote the movement of purified organelles along microtubules, suggesting that additional axoplasmic factors are necessary for retrograde as well as anterograde transport

  9. 41 CFR 101-25.110-3 - Tires accompanying new motor vehicles.

    Science.gov (United States)

    2010-07-01

    ... motor vehicles. 101-25.110-3 Section 101-25.110-3 Public Contracts and Property Management Federal...-GENERAL 25.1-General Policies § 101-25.110-3 Tires accompanying new motor vehicles. The tire identifications and recordkeeping regulations issued by the Department of Transportation require each motor...

  10. NanoShuttles: Harnessing Motor Proteins to Transport Cargo in Synthetic Environments

    Science.gov (United States)

    Vogel, V.; Hess, H.

    Motors have become a crucial commodity in our daily lives, from transportation to driving conveyor belts that enable the sequential assembly of cars and other industrial machines. For the sequential assembly of building blocks at the nanoscale that would not assemble spontaneously into larger functional systems, however, active transport systems are not yet available. In contrast, cells have evolved sophisticated molecular machinery that drives movement and active transport. Driven by the conversion of chemical into mechanical energy, namely through hydrolysis of the biological fuel ATP, molecular motors enable cells to operate far away from equilibrium by transporting organelles and molecules to designated locations within the cell, often against concentration gradients. Inspired by the biological concept of active transport, major efforts are underway to learn how to build nanoscale transport systems that are driven by molecular motors. Emerging engineering principles are discussed of how to build tracks and junctions to guide such nanoshuttles, how to load them with cargo and control their speed, how to use active transport to assemble mesoscopic structures that would otherwise not assemble spontaneously and what polymeric materials to choose to integrate motors into MEMS and other biohybrid devices. Finally, two applications that exploit the physical properties of microtubules are discussed, surface imaging by a swarm of microtubules and a self-assembled picoNewton force meter to probe receptor-ligand interactions.

  11. Motor Fuel Excise Taxes

    Energy Technology Data Exchange (ETDEWEB)

    2015-09-01

    A new report from the National Renewable Energy Laboratory (NREL) explores the role of alternative fuels and energy efficient vehicles in motor fuel taxes. Throughout the United States, it is common practice for federal, state, and local governments to tax motor fuels on a per gallon basis to fund construction and maintenance of our transportation infrastructure. In recent years, however, expenses have outpaced revenues creating substantial funding shortfalls that have required supplemental funding sources. While rising infrastructure costs and the decreasing purchasing power of the gas tax are significant factors contributing to the shortfall, the increased use of alternative fuels and more stringent fuel economy standards are also exacerbating revenue shortfalls. The current dynamic places vehicle efficiency and petroleum use reduction polices at direct odds with policies promoting robust transportation infrastructure. Understanding the energy, transportation, and environmental tradeoffs of motor fuel tax policies can be complicated, but recent experiences at the state level are helping policymakers align their energy and environmental priorities with highway funding requirements.

  12. Molecular motor transport through hollow nanowires

    DEFF Research Database (Denmark)

    Lard, Mercy; Ten Siethoff, Lasse; Generosi, Johanna

    2014-01-01

    -driven motion of fluorescent probes (actin filaments) through 80 nm wide, Al2O 3 hollow nanowires of micrometer length. The motor-driven transport is orders of magnitude faster than would be possible by passive diffusion. The system represents a necessary element for advanced devices based on gliding assays...

  13. 77 FR 22637 - Federal Motor Vehicle Safety Standards; Accelerator Control Systems

    Science.gov (United States)

    2012-04-16

    ... revise the Federal Motor Vehicle Safety Standard for accelerator control systems (ACS) in two ways. First... Standard (FMVSS) No. 124, Accelerator Control Systems,\\2\\ in two ways. First, we are proposing to update... February 2011 final report ``Technical Assessment of Toyota Electronic Throttle Control Systems,'' the...

  14. 76 FR 41181 - Federal Motor Vehicle Safety Standards; Lamps, Reflective Devices, and Associated Equipment

    Science.gov (United States)

    2011-07-13

    ... to restore the blue and green color boundaries to Federal Motor Vehicle Safety Standard (FMVSS) No... number in the heading of this document, by any of the following methods: Federal eRulemaking Portal: Go... comment, if submitted on behalf of an association, business, labor union, etc.). You may review DOT's...

  15. 76 FR 53660 - Federal Motor Vehicle Safety Standards; Seat Belt Assemblies

    Science.gov (United States)

    2011-08-29

    ... Traffic Safety Administration 49 CFR Part 571 [Docket No. NHTSA-2011-0078] Federal Motor Vehicle Safety... integration of electrical signals from vehicle crash sensors would work with the requested mechanical seat... (350,000) of the vehicles were stopped in the traffic lane prior to the crash event (pg. 22, Table 7...

  16. 75 FR 59103 - Defense Federal Acquisition Regulation Supplement; Motor Carrier Fuel Surcharge (DFARS Case 2008...

    Science.gov (United States)

    2010-09-27

    ...-AG30 Defense Federal Acquisition Regulation Supplement; Motor Carrier Fuel Surcharge (DFARS Case 2008... comments is provided below: 1. Comment. One respondent stated that it is customary in the motor carrier freight industry to assume a fixed cost of diesel fuel with a cost recovery mechanism (fuel surcharge) for...

  17. 75 FR 51392 - Federal Management Regulation; Transportation Management

    Science.gov (United States)

    2010-08-20

    ...; Docket Number 2010-0011, sequence 1] RIN 3090-AJ03 Federal Management Regulation; Transportation Management AGENCY: Office of Governmentwide Policy, General Services Administration (GSA). ACTION: Final rule. SUMMARY: The General Services Administration (GSA) is amending the Federal Management Regulation (FMR) by...

  18. Long-range cargo transport on crowded microtubules: The motor jamming mechanism

    Science.gov (United States)

    Rossi, Lucas W.; Radtke, Paul K.; Goldman, Carla

    2014-05-01

    The hopping model for cargo transport by molecular motors introduced in Goldman and Sena (2009), Goldman (2010) is extended here in order to incorporate the movement of cargo-motor complexes (C-MC). Hopping processes in this context express the possibility for cargo to be exchanged between neighboring motors at a microtubule where the transport takes place. Jamming of motors is essential for cargos to execute long-range movement in this way. Results from computer simulations accompanied by a mean-field analysis of the extended model confirm our previous analytical results and suggests that an interplay between cargo hopping and the movement of the C-MC’s would control the efficiency of cargo transfer and cargo delivery in these model systems.

  19. Motor carrier evaluation program plan

    International Nuclear Information System (INIS)

    Portsmouth, J.H.; Maxwell, J.E.; Boness, G.O.; Rice, L.E.

    1991-04-01

    The US Department of Energy (DOE) Transportation Management Program (TMP) has established a program to assist the DOE field offices and their contractors in evaluating the motor carriers used to transport DOE-owned hazardous and radioactive materials. This program was initiated to provide the DOE field offices with the tools necessary to help ensure, during this period of motor carrier deregulation, that only highly qualified carriers transport radioactive and hazardous commodities for the DOE. This program will assist DOE in maintaining their excellent performance record in the safe transportation of hazardous commodities. The program was also developed in response to public concern surrounding the transportation of hazardous materials. Representatives of other federal agencies, states, and tribal governments, as well as the news media, have expressed concern about the selection and qualification of carriers engaged in the transportation of Highway Route-Controlled Quantities (HRCQ) and Truckload (TL) quantities of radioactive material for the DOE. 8 refs

  20. 78 FR 16189 - Transportation of Agricultural Commodities

    Science.gov (United States)

    2013-03-14

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration 49 CFR Parts 382, 383, 390, 391, 395, 396 [Docket No. FMCSA-2012-0378] RIN 2126-AB58 Transportation of Agricultural...: FMCSA promulgates the regulatory exemptions for the ``transportation of agricultural commodities and...

  1. Transportation of drug–gold nanocomposites by actinomyosin motor system

    International Nuclear Information System (INIS)

    Kaur, Harsimran; Chaudhary, Archana; Kaur, Inderpreet; Singh, Kashmir; Bharadwaj, Lalit M.

    2011-01-01

    Nanotechnology is playing an important role in drug delivery to overcome limitations of conventional drug delivery systems in terms of solubility, in vivo stability, pharmacokinetics, and bio-distribution. The controlled transportation of drug into the cell and within the cell is a major challenge to be addressed. Cellular molecular motors have been exploited for their cargo carrying capacity for various applications including engineering and health care. Combination of nanotechnology and biomolecular motors can address some of the challenges in drug delivery. In the present study, transportation of drug nanocomposites has been demonstrated. Nanocomposites of 6-mercaptopurine and levodopa drugs (cancer and Parkinson’s disease, respectively) were prepared with gold nanoparticles (GNPs) by covalent attachment and these nanocomposites were attached to actin filaments. These nanocomposites were in-turn transported by actin filaments on myosin tracks. Characterization of drug nanocomposites formation was done by UV–Vis spectroscopy, field emission scanning electron microscopy, transmission electron microscopy, and confocal microscopy. GNP composites of 6-mercaptopurine and levodopa were formed by sulfide and amide bond formation, respectively. Average velocity of actin filament attached to nanocomposites was found to be 3.17 and 3.89 μm/s for levodopa and 6-mercaptopurine, respectively, as compared to actin filaments with velocity of 4.0–6.0 μm/s. Three concepts have been proposed for the study of drug transportation into the cell based on polycationic complex formation, interaction of actin with cellular myosin and Biomolecular Adaptor for Retrograde Transport (BART) technology. The aspects of this study heads toward the development of an approach to utilize molecular motors for nanoscale transportation endogenously.

  2. Transportation of drug-gold nanocomposites by actinomyosin motor system

    Science.gov (United States)

    Kaur, Harsimran; Chaudhary, Archana; Kaur, Inderpreet; Singh, Kashmir; Bharadwaj, Lalit M.

    2011-06-01

    Nanotechnology is playing an important role in drug delivery to overcome limitations of conventional drug delivery systems in terms of solubility, in vivo stability, pharmacokinetics, and bio-distribution. The controlled transportation of drug into the cell and within the cell is a major challenge to be addressed. Cellular molecular motors have been exploited for their cargo carrying capacity for various applications including engineering and health care. Combination of nanotechnology and biomolecular motors can address some of the challenges in drug delivery. In the present study, transportation of drug nanocomposites has been demonstrated. Nanocomposites of 6-mercaptopurine and levodopa drugs (cancer and Parkinson's disease, respectively) were prepared with gold nanoparticles (GNPs) by covalent attachment and these nanocomposites were attached to actin filaments. These nanocomposites were in-turn transported by actin filaments on myosin tracks. Characterization of drug nanocomposites formation was done by UV-Vis spectroscopy, field emission scanning electron microscopy, transmission electron microscopy, and confocal microscopy. GNP composites of 6-mercaptopurine and levodopa were formed by sulfide and amide bond formation, respectively. Average velocity of actin filament attached to nanocomposites was found to be 3.17 and 3.89 μm/s for levodopa and 6-mercaptopurine, respectively, as compared to actin filaments with velocity of 4.0-6.0 μm/s. Three concepts have been proposed for the study of drug transportation into the cell based on polycationic complex formation, interaction of actin with cellular myosin and Biomolecular Adaptor for Retrograde Transport (BART) technology. The aspects of this study heads toward the development of an approach to utilize molecular motors for nanoscale transportation endogenously.

  3. Transportation of drug-gold nanocomposites by actinomyosin motor system

    Energy Technology Data Exchange (ETDEWEB)

    Kaur, Harsimran, E-mail: microsimbac@gmail.com; Chaudhary, Archana; Kaur, Inderpreet [Council of Scientific and Industrial Research (CSIR), Biomolecular Electronics and Nanotechnology Division (BEND), Central Scientific Instruments Organization - CSIO (India); Singh, Kashmir [Panjab University, Department of Biotechnology (India); Bharadwaj, Lalit M. [Council of Scientific and Industrial Research (CSIR), Biomolecular Electronics and Nanotechnology Division (BEND), Central Scientific Instruments Organization - CSIO (India)

    2011-06-15

    Nanotechnology is playing an important role in drug delivery to overcome limitations of conventional drug delivery systems in terms of solubility, in vivo stability, pharmacokinetics, and bio-distribution. The controlled transportation of drug into the cell and within the cell is a major challenge to be addressed. Cellular molecular motors have been exploited for their cargo carrying capacity for various applications including engineering and health care. Combination of nanotechnology and biomolecular motors can address some of the challenges in drug delivery. In the present study, transportation of drug nanocomposites has been demonstrated. Nanocomposites of 6-mercaptopurine and levodopa drugs (cancer and Parkinson's disease, respectively) were prepared with gold nanoparticles (GNPs) by covalent attachment and these nanocomposites were attached to actin filaments. These nanocomposites were in-turn transported by actin filaments on myosin tracks. Characterization of drug nanocomposites formation was done by UV-Vis spectroscopy, field emission scanning electron microscopy, transmission electron microscopy, and confocal microscopy. GNP composites of 6-mercaptopurine and levodopa were formed by sulfide and amide bond formation, respectively. Average velocity of actin filament attached to nanocomposites was found to be 3.17 and 3.89 {mu}m/s for levodopa and 6-mercaptopurine, respectively, as compared to actin filaments with velocity of 4.0-6.0 {mu}m/s. Three concepts have been proposed for the study of drug transportation into the cell based on polycationic complex formation, interaction of actin with cellular myosin and Biomolecular Adaptor for Retrograde Transport (BART) technology. The aspects of this study heads toward the development of an approach to utilize molecular motors for nanoscale transportation endogenously.

  4. 75 FR 6253 - Petition for Exemption From the Federal Motor Vehicle Theft Prevention Standard; Hyundia-Kia...

    Science.gov (United States)

    2010-02-08

    ... From the Federal Motor Vehicle Theft Prevention Standard; Hyundia-Kia America Technical Center, Inc..., Exemption from Vehicle Theft Prevention Standard. This petition is granted because the agency has determined... in reducing and deterring motor vehicle theft as compliance with the parts-marking requirements of 49...

  5. An exact approach for studying cargo transport by an ensemble of molecular motors

    International Nuclear Information System (INIS)

    Materassi, Donatello; Roychowdhury, Subhrajit; Hays, Thomas; Salapaka, Murti

    2013-01-01

    Intracellular transport is crucial for many cellular processes where a large fraction of the cargo is transferred by motor-proteins over a network of microtubules. Malfunctions in the transport mechanism underlie a number of medical maladies. Existing methods for studying how motor-proteins coordinate the transfer of a shared cargo over a microtubule are either analytical or are based on Monte-Carlo simulations. Approaches that yield analytical results, while providing unique insights into transport mechanism, make simplifying assumptions, where a detailed characterization of important transport modalities is difficult to reach. On the other hand, Monte-Carlo based simulations can incorporate detailed characteristics of the transport mechanism; however, the quality of the results depend on the number and quality of simulation runs used in arriving at results. Here, for example, it is difficult to simulate and study rare-events that can trigger abnormalities in transport. In this article, a semi-analytical methodology that determines the probability distribution function of motor-protein behavior in an exact manner is developed. The method utilizes a finite-dimensional projection of the underlying infinite-dimensional Markov model, which retains the Markov property, and enables the detailed and exact determination of motor configurations, from which meaningful inferences on transport characteristics of the original model can be derived. Under this novel probabilistic approach new insights about the mechanisms of action of these proteins are found, suggesting hypothesis about their behavior and driving the design and realization of new experiments. The advantages provided in accuracy and efficiency make it possible to detect rare events in the motor protein dynamics, that could otherwise pass undetected using standard simulation methods. In this respect, the model has allowed to provide a possible explanation for possible mechanisms under which motor proteins could

  6. 78 FR 67213 - Petition for Exemption From the Federal Motor Vehicle Theft Prevention Standard; Porsche Cars...

    Science.gov (United States)

    2013-11-08

    ... From the Federal Motor Vehicle Theft Prevention Standard; Porsche Cars North America, Inc. AGENCY... From Vehicle Theft Prevention Standard. This petition is granted because the agency has determined that... reducing and deterring motor vehicle theft as compliance with the parts-marking requirements of the 49 CFR...

  7. 75 FR 60036 - Federal Motor Vehicle Safety Standards; New Pneumatic Tires for Motor Vehicles With a GVWR of...

    Science.gov (United States)

    2010-09-29

    ... evaluates resistance to heat buildup when the tire is run at stepped-up loads at or near its rated load... that involves a tire running on the roadwheel under specified conditions to allow for tire growth. The... [Docket No. NHTSA-2010-0132] RIN 2127-AK17 Federal Motor Vehicle Safety Standards; New Pneumatic Tires for...

  8. Mechanical coupling of microtubule-dependent motor teams during peroxisome transport in Drosophila S2 cells.

    Science.gov (United States)

    De Rossi, María Cecilia; Wetzler, Diana E; Benseñor, Lorena; De Rossi, María Emilia; Sued, Mariela; Rodríguez, Daniela; Gelfand, Vladimir; Bruno, Luciana; Levi, Valeria

    2017-12-01

    Intracellular transport requires molecular motors that step along cytoskeletal filaments actively dragging cargoes through the crowded cytoplasm. Here, we explore the interplay of the opposed polarity motors kinesin-1 and cytoplasmic dynein during peroxisome transport along microtubules in Drosophila S2 cells. We used single particle tracking with nanometer accuracy and millisecond time resolution to extract quantitative information on the bidirectional motion of organelles. The transport performance was studied in cells expressing a slow chimeric plus-end directed motor or the kinesin heavy chain. We also analyzed the influence of peroxisomes membrane fluidity in methyl-β-ciclodextrin treated cells. The experimental data was also confronted with numerical simulations of two well-established tug of war scenarios. The velocity distributions of retrograde and anterograde peroxisomes showed a multimodal pattern suggesting that multiple motor teams drive transport in either direction. The chimeric motors interfered with the performance of anterograde transport and also reduced the speed of the slowest retrograde team. In addition, increasing the fluidity of peroxisomes membrane decreased the speed of the slowest anterograde and retrograde teams. Our results support the existence of a crosstalk between opposed-polarity motor teams. Moreover, the slowest teams seem to mechanically communicate with each other through the membrane to trigger transport. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Growth of motorized mobility and strategies for road safety. Paper to be published in Transport Miesjki (Public Transport), 1993, No. 9 (Polish).

    NARCIS (Netherlands)

    Koornstra, M.J.

    2012-01-01

    Free market economies have shown the dominating utility of motorized transport, both for passenger and goods transport. One negative side of motorization is the lack of road safety. Although it is shown that air, water and rail transport are much safer, the individual and company utility of

  10. 78 FR 2797 - Federal Motor Vehicle Safety Standards; Minimum Sound Requirements for Hybrid and Electric Vehicles

    Science.gov (United States)

    2013-01-14

    ... Sound Requirements for Hybrid and Electric Vehicles; Draft Environmental Assessment for Rulemaking To Establish Minimum Sound Requirements for Hybrid and Electric Vehicles; Proposed Rules #0;#0;Federal Register...-0148] RIN 2127-AK93 Federal Motor Vehicle Safety Standards; Minimum Sound Requirements for Hybrid and...

  11. Intracellular Transport: How Do Motors Work Together?

    Science.gov (United States)

    Mallik, Roop; Gross, Steven P.

    2010-01-01

    How many motors move cargos on microtubules inside a cell, and how do they work together to achieve regulated transport? A new study uses an optical trap to investigate the motion of protein-bound beads on the surface of flagella to address these questions and comes up with some intriguing answers. PMID:19467211

  12. 78 FR 15920 - Federal Motor Vehicle Safety Standards; Tire Selection and Rims

    Science.gov (United States)

    2013-03-13

    ... [Docket No. NHTSA-2013-0030] RIN 2127-AL24 Federal Motor Vehicle Safety Standards; Tire Selection and Rims... Safety Standard (FMVSS) No. 110 to make it clear that special trailer (ST) tires are permitted to be... also proposes to exclude these trailers from a vehicle testing requirement that a tire must be retained...

  13. 41 CFR 102-34.250 - Do Federal employees in Government motor vehicles have to use all safety devices and follow all...

    Science.gov (United States)

    2010-07-01

    ... safety devices and follow all safety guidelines? Yes, Federal employees in Government motor vehicles have... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Do Federal employees in Government motor vehicles have to use all safety devices and follow all safety guidelines? 102-34.250 Section...

  14. Efficacy of Web-Based Instruction to Provide Training on Federal Motor Carrier Safety Regulations

    Science.gov (United States)

    2011-05-01

    This report presents an evaluation of the current state-of-the-art Web-based instruction (WBI), reviews the current computer platforms of potential users of WBI, reviews the current status of WBI applications for Federal Motor Carrier Safety Administ...

  15. Alternative Transportation System Demand Estimation for Federal Land Management Agencies.

    Science.gov (United States)

    2011-09-30

    Estimating travel demand for alternative transportation systems (ATS) is challenging in any context, but is even more daunting for Federal Land Management Agencies (FLMAs). Federal public land sites vary widely in their characteristics. Moreover, tra...

  16. A projection of motor fuel tax revenue and analysis of alternative revenue sources in Georgia.

    Science.gov (United States)

    2012-05-01

    Motor fuel tax revenue currently supplies the majority of funding for : transportation agencies at the state and federal level. Georgia uses excise and sales taxes : to generate revenue for the Georgia Department of Transportation (GDOT). Inflation a...

  17. 40 CFR 80.583 - What alternative sampling and testing requirements apply to importers who transport motor vehicle...

    Science.gov (United States)

    2010-07-01

    ... requirements apply to importers who transport motor vehicle diesel fuel, NRLM diesel fuel, or ECA marine fuel... (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Motor Vehicle Diesel Fuel... alternative sampling and testing requirements apply to importers who transport motor vehicle diesel fuel, NRLM...

  18. 41 CFR 109-40.103-3 - International transportation.

    Science.gov (United States)

    2010-07-01

    ... transportation. 109-40.103-3 Section 109-40.103-3 Public Contracts and Property Management Federal Property..., TRANSPORTATION, AND MOTOR VEHICLES 40-TRANSPORTATION AND TRAFFIC MANAGEMENT 40.1-General Provision § 109-40.103-3 International transportation. See 4 CFR 52.2 for a certificate required in nonuse of U.S. flag vessels or U.S...

  19. How molecular motors are arranged on a cargo is important for vesicular transport.

    Directory of Open Access Journals (Sweden)

    Robert P Erickson

    2011-05-01

    Full Text Available The spatial organization of the cell depends upon intracellular trafficking of cargos hauled along microtubules and actin filaments by the molecular motor proteins kinesin, dynein, and myosin. Although much is known about how single motors function, there is significant evidence that cargos in vivo are carried by multiple motors. While some aspects of multiple motor function have received attention, how the cargo itself--and motor organization on the cargo--affects transport has not been considered. To address this, we have developed a three-dimensional Monte Carlo simulation of motors transporting a spherical cargo, subject to thermal fluctuations that produce both rotational and translational diffusion. We found that these fluctuations could exert a load on the motor(s, significantly decreasing the mean travel distance and velocity of large cargos, especially at large viscosities. In addition, the presence of the cargo could dramatically help the motor to bind productively to the microtubule: the relatively slow translational and rotational diffusion of moderately sized cargos gave the motors ample opportunity to bind to a microtubule before the motor/cargo ensemble diffuses out of range of that microtubule. For rapidly diffusing cargos, the probability of their binding to a microtubule was high if there were nearby microtubules that they could easily reach by translational diffusion. Our simulations found that one reason why motors may be approximately 100 nm long is to improve their 'on' rates when attached to comparably sized cargos. Finally, our results suggested that to efficiently regulate the number of active motors, motors should be clustered together rather than spread randomly over the surface of the cargo. While our simulation uses the specific parameters for kinesin, these effects result from generic properties of the motors, cargos, and filaments, so they should apply to other motors as well.

  20. Local synaptic signaling enhances the stochastic transport of motor-driven cargo in neurons

    KAUST Repository

    Newby, Jay; Bressloff, Paul C

    2010-01-01

    The tug-of-war model of motor-driven cargo transport is formulated as an intermittent trapping process. An immobile trap, representing the cellular machinery that sequesters a motor-driven cargo for eventual use, is located somewhere within a

  1. Primer on Motor Fuel Excise Taxes and the Role of Alternative Fuels and Energy Efficient Vehicles

    Energy Technology Data Exchange (ETDEWEB)

    Schroeder, Alex [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2015-08-26

    Motor fuel taxes were established to finance our nation’s transportation infrastructure, yet evolving economic, political, and technological influences are constraining this ability. At the federal level, the Highway Trust Fund (HTF), which is primarily funded by motor fuel taxes, has become increasingly dependent on general fund contributions and short-term reauthorizations to prevent insolvency. As a result, there are discussions at both the federal and state levels in which stakeholders are examining the future of motor fuel excise taxes as well as the role of electric and alternative fuel vehicles in that future. On July 1, 2015, six states increased their motor fuel tax rates.

  2. Evidence report : psychiatric disorders and commercial motor vehicle driver safety.

    Science.gov (United States)

    2008-08-29

    This report was prepared by ECRI Institute under subcontract to MANILA Consulting Group, Inc., which holds prime GS-10F-0177N/DTMC75-06-F-00039 with the Department of Transportations Federal Motor Carrier Safety Administration. ECRI Institute is a...

  3. 75 FR 10267 - Federal Acquisition Regulation; Submission for OMB Review; Contractor Use of Interagency Motor...

    Science.gov (United States)

    2010-03-05

    ... ADMINISTRATION [OMB Control No. 9000-0032] Federal Acquisition Regulation; Submission for OMB Review; Contractor... previously approved information collection requirement concerning contractor use of interagency motor pool... contracting officer may authorize cost-reimbursement contractors to obtain, for official purposes only...

  4. 76 FR 78 - Federal Motor Vehicle Safety Standard; Engine Control Module Speed Limiter Device

    Science.gov (United States)

    2011-01-03

    ... [Docket No. NHTSA-2007-26851] Federal Motor Vehicle Safety Standard; Engine Control Module Speed Limiter... occupants. IIHS stated that on-board electronic engine control modules (ECM) will maintain the desired speed... be equipped with an electronic control module (ECM) that is capable of limiting the maximum speed of...

  5. 77 FR 17105 - Identification of Interstate Motor Vehicles: City of Chicago, IL Registration Emblem Requirement...

    Science.gov (United States)

    2012-03-23

    ... section 31704; (2) Under the International Fuel Tax Agreement under section 31705 or under an applicable... through the International Fuel Tax Agreement; (3) Under a State law regarding motor vehicle license plates... Chicago Ground Transportation Tax is preempted by Federal law. Federal law prohibits States and their...

  6. 76 FR 49532 - Federal Motor Vehicle Safety Standards; Electronic Stability Control; Technical Report on the...

    Science.gov (United States)

    2011-08-10

    ...-0112] Federal Motor Vehicle Safety Standards; Electronic Stability Control; Technical Report on the Effectiveness of Electronic Stability Control Systems for Cars and LTVs AGENCY: National Highway Traffic Safety..., Electronic Stability Control Systems. The report's title is: Crash Prevention Effectiveness in Light-Vehicle...

  7. Compendium of federal and state radioactive materials transportation laws and regulations: Transportation Legislative Database (TLDB)

    International Nuclear Information System (INIS)

    1989-10-01

    The Transportation Legislative Database (TLDB) is an on-line information service containing detailed information on legislation and regulations regarding the transportation of radioactive materials in the United States. The system is dedicated to serving the legislative and regulatory information needs of the US Department of Energy and other federal agencies; state, tribal, and local governments; the hazardous materials transportation industry; and interested members of the general public. In addition to the on-line information service, quarterly and annual Legal Developments Reports are produced using information from the TLDB. These reports summarize important changes in federal and state legislation, regulations, administrative agency rulings, and judicial decisions over the reporting period. Information on significant legal developments at the tribal and local levels is also included on an as-available basis. Battelle's Office of Transportation Systems and Planning (OTSP) will also perform customized searches of the TLDB and produce formatted printouts in response to specific information requests

  8. Toward a federal/state/local partnership in hazardous materials transportation safety

    International Nuclear Information System (INIS)

    1982-09-01

    In recognition of the federal government's responsibility for initiating a national strategy for hazardous materials transportation safety, the Materials Transportation Bureau (MTB) prepared an internal strategy paper for creating a federal/state/local partnership in hazardous materials transportation safety in August 1981. The paper outlined the scope of the hazardous materials transportation problem and established MTB's approach for creating an intergovernmental partnership for its resolution. This paper represents an update and refinement of the original plan, and is designed to chart the direction of the emerging federal/state/local relationship. The cornerstone of the plan remains the establishment of a single national set of safety regulations. It is on achievement of this objective that MTB's plan for development of enforcement, training, and emergency response capabilities at all levels of government is based. Chapter I introduces the problem with a desription of the economic importance of hazardous materials and discusses its implications for public safety. Chapter II defines the appropriate role for each level of government in the areas of rulemaking, enforcement, emergency response, and education. Chapter III demonstrates the need for uniform national safety standards and describes the economic and safety benefits of this approach. Chapter IV contains a detailed description of MTB's program for developing a successful intergovernmental partnership in hazardous materials transportation safety

  9. Application of quasi-steady state methods to molecular motor transport on microtubules in fungal hyphae.

    Science.gov (United States)

    Dauvergne, Duncan; Edelstein-Keshet, Leah

    2015-08-21

    We consider bidirectional transport of cargo by molecular motors dynein and kinesin that walk along microtubules, and/or diffuse in the cell. The motors compete to transport cargo in opposite directions with respect to microtubule polarity (towards the plus or minus end of the microtubule). In recent work, Gou et al. (2014) used a hierarchical set of models, each consisting of continuum transport equations to track the evolution of motors and their cargo (early endosomes) in the specific case of the fungus Ustilago maydis. We complement their work using a framework of quasi-steady state analysis developed by Newby and Bressloff (2010) and Bressloff and Newby (2013) to reduce the models to an approximating steady state Fokker-Plank equation. This analysis allows us to find analytic approximations to the steady state solutions in many cases where the full models are not easily solved. Consequently, we can make predictions about parameter dependence of the resulting spatial distributions. We also characterize the overall rates of bulk transport and diffusion, and how these are related to state transition parameters, motor speeds, microtubule polarity distribution, and specific assumptions made. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Federal legal constraints on state and local regulation of radioactive materials transportation

    International Nuclear Information System (INIS)

    Reese, R.T.; Morris, F.A.; Welles, B.W.

    1980-01-01

    Within the last five years, the transportation of nuclear materials has experienced a rapid growth of state/local regulations. The federal government is responding to develop a legal basis for declaring these state/local regulations inconsistent and has proceeded to declare certain state regulations invalid. This paper summarizes the relevant legal doctrines, places these doctrines in the context of the federal regulatory framework and reaches conclusions about what forms of state and local regulation may be subject to possible preemptive initiatives and what regulations are unlikely candidates for federal actions. This paper also discusses an example of a preemptive initiative and a federal action. The initiative is contained in DOT's proposed rule on Highway Routing of Radioactive Materials. DOT's first general preemptive action under the Hazardous Materials Transportation Act is described with respect to decisions on Rhode Island's regulations regarding transportation of liquified natural and petroleum gases. There are still some issues that have not been clarified - the role of the federal government in the development and support of emergency response capabilities for nuclear and other hazardous materials, detailed shipment information, and state requirements for prenotifications

  11. Assessing the Impact of Electrostatic Drag on Processive Molecular Motor Transport.

    Science.gov (United States)

    Smith, J Darby; McKinley, Scott A

    2018-06-04

    The bidirectional movement of intracellular cargo is usually described as a tug-of-war among opposite-directed families of molecular motors. While tug-of-war models have enjoyed some success, recent evidence suggests underlying motor interactions are more complex than previously understood. For example, these tug-of-war models fail to predict the counterintuitive phenomenon that inhibiting one family of motors can decrease the functionality of opposite-directed transport. In this paper, we use a stochastic differential equations modeling framework to explore one proposed physical mechanism, called microtubule tethering, that could play a role in this "co-dependence" among antagonistic motors. This hypothesis includes the possibility of a trade-off: weakly bound trailing molecular motors can serve as tethers for cargoes and processing motors, thereby enhancing motor-cargo run lengths along microtubules; however, this introduces a cost of processing at a lower mean velocity. By computing the small- and large-time mean-squared displacement of our theoretical model and comparing our results to experimental observations of dynein and its "helper protein" dynactin, we find some supporting evidence for microtubule tethering interactions. We extrapolate these findings to predict how dynein-dynactin might interact with the opposite-directed kinesin motors and introduce a criterion for when the trade-off is beneficial in simple systems.

  12. 49 CFR 1.73 - Delegation to the Administrator of the Federal Motor Carrier Safety Administration.

    Science.gov (United States)

    2010-10-01

    ... to remove, to the maximum extent practicable, a worst case discharge, the review and approval of... movie production sites; (9) Section 4134 relating to the grant program for persons to train operators of...; section (b)(1) relating to a review of Canadian and Mexican compliance with Federal motor vehicles safety...

  13. 48 CFR 970.5223-6 - Executive Order 13423, Strengthening Federal Environmental, Energy, and Transportation Management.

    Science.gov (United States)

    2010-10-01

    ..., Strengthening Federal Environmental, Energy, and Transportation Management. 970.5223-6 Section 970.5223-6... FEDERAL ENVIRONMENTAL, ENERGY, AND TRANSPORTATION MANAGEMENT (OCT 2010) Since this contract involves... MANAGEMENT AND OPERATING CONTRACTS Solicitation Provisions and Contract Clauses for Management and Operating...

  14. 75 FR 51521 - Federal Motor Vehicle Safety Standards; Air Brake Systems; Technical Report on the Effectiveness...

    Science.gov (United States)

    2010-08-20

    ....121) mandates antilock braking systems (ABS) on all new air-braked vehicles with a GVWR of 10,000...-0116] Federal Motor Vehicle Safety Standards; Air Brake Systems; Technical Report on the Effectiveness of Antilock Braking Systems in Heavy Truck Tractors and Trailers AGENCY: National Highway Traffic...

  15. Equivalent mechanical parameters of oscillating rotary motors used in transport equipment

    Directory of Open Access Journals (Sweden)

    A. Andziulis

    2006-12-01

    Full Text Available In various appliances and equipment of sundry transport means there is a lot of diverse mechanisms of periodical movement. So, the various piston or membrane pumps of fuel feeding and lubrication systems, circulation pumps, air and refrigerating coolant compressors, etc. are the typical examples of innovative and well promising application of the oscillating motors. In these cases the moving part of a motor can be directly connected to the working body of driven mechanism without the additional gears. Consequently, the drive can be simplified in design and improved in efficiency and reliability. Application of the oscillating rotary motors, if used in the aforesaid devices, strictly depends on specific properties of mechanical system of a motor aggregated with the driven mechanism and considered as the one-piece unit on the whole. So, this study analyses how the properties of mechanical system, comprised of two moving parts interconnected eccentrically or centrically, can be evaluated by the equivalent rotational inertia, equivalent mass and by equivalent mechanical power factor which, in turn, determine the operating characteristics and basic possibilities of the motor.

  16. 76 FR 11415 - Federal Motor Vehicle Safety Standards; Power-Operated Window, Partition, and Roof Panel Systems

    Science.gov (United States)

    2011-03-02

    ... [Docket No. NHTSA-2011-0027] RIN 2127-AK52 Federal Motor Vehicle Safety Standards; Power-Operated Window, Partition, and Roof Panel Systems AGENCY: National Highway Traffic Safety Administration (NHTSA), Department... automatic reversal systems (ARS) for power windows and to make a final decision. The agency has decided not...

  17. Exercise-induced expression of monocarboxylate transporter 2 in the cerebellum and its contribution to motor performance.

    Science.gov (United States)

    Hoshino, Daisuke; Setogawa, Susumu; Kitaoka, Yu; Masuda, Hiroyuki; Tamura, Yuki; Hatta, Hideo; Yanagihara, Dai

    2016-10-28

    Monocarboxylate transporter 2 (MCT2) is an important component of the lactate transport system in neurons of the adult brain. Purkinje cells in the cerebellum have been shown to have high levels of MCT2, suggesting that this protein has a key function in energy metabolism and neuronal activities in these cells. However, it is not known whether inhibition of lactate transport via MCT2 in the cerebellum affects motor performance. To address this question, we examined motor performance in mice following the inhibition of lactate transport via MCT2 in the cerebellum using α-cyano-4-hydroxycinnamate (4-CIN). 4-CIN or saline was injected into the subarachnoidal space of the cerebellum of mice and motor performance was analyzed by a rotarod test both before and after injection. 4-CIN injection reduced retention time in the rotarod test by approximately 80% at 1h post-injection compared with pre-injection. No effect was observed at 2h post-injection or in mice treated with the vehicle control. Because we observed that MCT2 plays an important role in motor performance, we next investigated the effects of acute exercise on MCT2 transcription and protein levels in mice sampled pre-exercise and at 0 and 5h after 2h of treadmill running. We found a significant increase in MCT2 mRNA levels, but not of protein levels, in the cerebellum at 5h after exercise. Our results indicate that lactate transport via MCT2 in the cerebellum may play an important role in motor performance and that exercise can increase MCT2 expression at the transcriptional level. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  18. Evidence Report : 2010 update, diabetes and commercial motor vehicle driver safety : May 27, 2011.

    Science.gov (United States)

    2011-05-27

    This report was prepared by MANILA Consulting Group, Inc. under Contract No. GS-10F-0177N; Order No. DTMC75-10-F-00013, entitled Medical Programs Research and Analysis Panels Project, with the Department of Transportations Federal Motor Carrier...

  19. 78 FR 36723 - Federal Management Regulation (FMR); Restrictions on International Transportation of Freight and...

    Science.gov (United States)

    2013-06-19

    ..., Sequence 1] RIN 3090-AJ34 Federal Management Regulation (FMR); Restrictions on International Transportation... Administration (GSA). ACTION: Proposed rule. SUMMARY: GSA is proposing to amend the Federal Management Regulation... Federal Management Regulation (FMR) to state clearly that this part applies to all agencies and wholly...

  20. 77 FR 42548 - Privacy Act of 1974; Department of Transportation, Federal Motor Carrier Safety Administration...

    Science.gov (United States)

    2012-07-19

    ... motor carrier business models which may include the use of industry service providers to directly hire... in secure facilities. Electronic records may be stored on magnetic disc, tape, digital media, and CD...

  1. 75 FR 38168 - Federal Motor Vehicle Theft Prevention Standard; Final Listing of 2011 Light Duty Truck Lines...

    Science.gov (United States)

    2010-07-01

    ... Theft Prevention Standard; Final Listing of 2011 Light Duty Truck Lines Subject to the Requirements of... light-duty truck lines subject to the requirements of the Federal motor vehicle theft prevention... exemption from the parts marking requirements of the Theft Prevention Standard for the Jaguar XJ vehicle...

  2. Motorized Transportation, Social Status, and Adiposity The China Health and Nutrition Survey

    NARCIS (Netherlands)

    Qin, Li; Stolk, Ronald P.; Corpeleijn, Eva

    Background: Increased dependence on motorized transportation may contribute to obesity. Countries in rapid socioeconomic transitions, such as China, provide an opportunity to investigate such an association. Purpose: The aim of the study was to examine the hypotheses that increased dependence on

  3. Forecastable and Guidable Bubble-Propelled Microplate Motors for Cell Transport.

    Science.gov (United States)

    Hu, Narisu; Zhang, Bin; Gai, Meiyu; Zheng, Ce; Frueh, Johannes; He, Qiang

    2017-06-01

    Cell transport is important to renew body functions and organs with stem cells, or to attack cancer cells with immune cells. The main hindrances of this method are the lack of understanding of cell motion as well as proper transport systems. In this publication, bubble-propelled polyelectrolyte microplates are used for controlled transport and guidance of HeLa cells. Cells survive attachment on the microplates and up to 22 min in 5% hydrogen peroxide solution. They can be guided by a magnetic field whereby increased friction of cells attached to microplates decreases the speed by 90% compared to pristine microplates. The motion direction of the cell-motor system is easier to predict due to the cell being opposite to the bubbles. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. 76 FR 647 - Energy Conservation Program: Test Procedures for Electric Motors and Small Electric Motors

    Science.gov (United States)

    2011-01-05

    ... Electric Motors and Small Electric Motors; Proposed Rule #0;#0;Federal Register / Vol. 76, No. 3... Motors and Small Electric Motors AGENCY: Office of Energy Efficiency and Renewable Energy, Department of... motors and small electric motors, clarify the scope of energy conservation standards for electric motors...

  5. Federal Fleet Report

    Data.gov (United States)

    General Services Administration — Annual report of Federal agencies' motor vehicle fleet data collected in the Federal Automotive Statistical Tool (FAST), a web-based reporting tool cosponsored by...

  6. Random intermittent search and the tug-of-war model of motor-driven transport

    International Nuclear Information System (INIS)

    Newby, Jay; Bressloff, Paul C

    2010-01-01

    We formulate the 'tug-of-war' model of microtubule cargo transport by multiple molecular motors as an intermittent random search for a hidden target. A motor complex consisting of multiple molecular motors with opposing directional preference is modeled using a discrete Markov process. The motors randomly pull each other off of the microtubule so that the state of the motor complex is determined by the number of bound motors. The tug-of-war model prescribes the state transition rates and corresponding cargo velocities in terms of experimentally measured physical parameters. We add space to the resulting Chapman–Kolmogorov (CK) equation so that we can consider delivery of the cargo to a hidden target at an unknown location along the microtubule track. The target represents some subcellular compartment such as a synapse in a neuron's dendrites, and target delivery is modeled as a simple absorption process. Using a quasi-steady-state (QSS) reduction technique we calculate analytical approximations of the mean first passage time (MFPT) to find the target. We show that there exists an optimal adenosine triphosphate (ATP) concentration that minimizes the MFPT for two different cases: (i) the motor complex is composed of equal numbers of kinesin motors bound to two different microtubules (symmetric tug-of-war model) and (ii) the motor complex is composed of different numbers of kinesin and dynein motors bound to a single microtubule (asymmetric tug-of-war model)

  7. Random intermittent search and the tug-of-war model of motor-driven transport

    Science.gov (United States)

    Newby, Jay; Bressloff, Paul C.

    2010-04-01

    We formulate the 'tug-of-war' model of microtubule cargo transport by multiple molecular motors as an intermittent random search for a hidden target. A motor complex consisting of multiple molecular motors with opposing directional preference is modeled using a discrete Markov process. The motors randomly pull each other off of the microtubule so that the state of the motor complex is determined by the number of bound motors. The tug-of-war model prescribes the state transition rates and corresponding cargo velocities in terms of experimentally measured physical parameters. We add space to the resulting Chapman-Kolmogorov (CK) equation so that we can consider delivery of the cargo to a hidden target at an unknown location along the microtubule track. The target represents some subcellular compartment such as a synapse in a neuron's dendrites, and target delivery is modeled as a simple absorption process. Using a quasi-steady-state (QSS) reduction technique we calculate analytical approximations of the mean first passage time (MFPT) to find the target. We show that there exists an optimal adenosine triphosphate (ATP) concentration that minimizes the MFPT for two different cases: (i) the motor complex is composed of equal numbers of kinesin motors bound to two different microtubules (symmetric tug-of-war model) and (ii) the motor complex is composed of different numbers of kinesin and dynein motors bound to a single microtubule (asymmetric tug-of-war model).

  8. Random intermittent search and the tug-of-war model of motor-driven transport

    KAUST Repository

    Newby, Jay

    2010-04-16

    We formulate the \\'tug-of-war\\' model of microtubule cargo transport by multiple molecular motors as an intermittent random search for a hidden target. A motor complex consisting of multiple molecular motors with opposing directional preference is modeled using a discrete Markov process. The motors randomly pull each other off of the microtubule so that the state of the motor complex is determined by the number of bound motors. The tug-of-war model prescribes the state transition rates and corresponding cargo velocities in terms of experimentally measured physical parameters. We add space to the resulting Chapman-Kolmogorov (CK) equation so that we can consider delivery of the cargo to a hidden target at an unknown location along the microtubule track. The target represents some subcellular compartment such as a synapse in a neuron\\'s dendrites, and target delivery is modeled as a simple absorption process. Using a quasi-steady-state (QSS) reduction technique we calculate analytical approximations of the mean first passage time (MFPT) to find the target. We show that there exists an optimal adenosine triphosphate (ATP) concentration that minimizes the MFPT for two different cases: (i) the motor complex is composed of equal numbers of kinesin motors bound to two different microtubules (symmetric tug-of-war model) and (ii) the motor complex is composed of different numbers of kinesin and dynein motors bound to a single microtubule (asymmetric tug-of-war model). © 2010 IOP Publishing Ltd.

  9. Random intermittent search and the tug-of-war model of motor-driven transport

    KAUST Repository

    Newby, Jay; Bressloff, Paul C

    2010-01-01

    We formulate the 'tug-of-war' model of microtubule cargo transport by multiple molecular motors as an intermittent random search for a hidden target. A motor complex consisting of multiple molecular motors with opposing directional preference is modeled using a discrete Markov process. The motors randomly pull each other off of the microtubule so that the state of the motor complex is determined by the number of bound motors. The tug-of-war model prescribes the state transition rates and corresponding cargo velocities in terms of experimentally measured physical parameters. We add space to the resulting Chapman-Kolmogorov (CK) equation so that we can consider delivery of the cargo to a hidden target at an unknown location along the microtubule track. The target represents some subcellular compartment such as a synapse in a neuron's dendrites, and target delivery is modeled as a simple absorption process. Using a quasi-steady-state (QSS) reduction technique we calculate analytical approximations of the mean first passage time (MFPT) to find the target. We show that there exists an optimal adenosine triphosphate (ATP) concentration that minimizes the MFPT for two different cases: (i) the motor complex is composed of equal numbers of kinesin motors bound to two different microtubules (symmetric tug-of-war model) and (ii) the motor complex is composed of different numbers of kinesin and dynein motors bound to a single microtubule (asymmetric tug-of-war model). © 2010 IOP Publishing Ltd.

  10. 77 FR 26607 - Energy Conservation Program: Test Procedures for Electric Motors and Small Electric Motors

    Science.gov (United States)

    2012-05-04

    ... Conservation Program: Test Procedures for Electric Motors and Small Electric Motors; Final Rules #0;#0;Federal... Procedures for Electric Motors and Small Electric Motors AGENCY: Office of Energy Efficiency and Renewable... electric motors and small electric motors. That supplemental proposal, along with an earlier proposal from...

  11. Models for microtubule cargo transport coupling the Langevin equation to stochastic stepping motor dynamics: Caring about fluctuations.

    Science.gov (United States)

    Bouzat, Sebastián

    2016-01-01

    One-dimensional models coupling a Langevin equation for the cargo position to stochastic stepping dynamics for the motors constitute a relevant framework for analyzing multiple-motor microtubule transport. In this work we explore the consistence of these models focusing on the effects of the thermal noise. We study how to define consistent stepping and detachment rates for the motors as functions of the local forces acting on them in such a way that the cargo velocity and run-time match previously specified functions of the external load, which are set on the base of experimental results. We show that due to the influence of the thermal fluctuations this is not a trivial problem, even for the single-motor case. As a solution, we propose a motor stepping dynamics which considers memory on the motor force. This model leads to better results for single-motor transport than the approaches previously considered in the literature. Moreover, it gives a much better prediction for the stall force of the two-motor case, highly compatible with the experimental findings. We also analyze the fast fluctuations of the cargo position and the influence of the viscosity, comparing the proposed model to the standard one, and we show how the differences on the single-motor dynamics propagate to the multiple motor situations. Finally, we find that the one-dimensional character of the models impede an appropriate description of the fast fluctuations of the cargo position at small loads. We show how this problem can be solved by considering two-dimensional models.

  12. Status and future aspects of nuclear fuel cycle transports in the Federal Republic of Germany

    International Nuclear Information System (INIS)

    Blechschmidt, M.; Keese, H.

    1977-01-01

    The transport practices in the Federal Republic of Germany for materials of the nuclear fuel cycle are discussed. Particularly containers and modes of transport for UF 6 , fresh and spent fuel elements, plutonium and radwaste are described, with main emphasis on transport to reprocessing and waste storage facilities. In most cases nuclear materials have to be shipped across the borders because at present neither an enrichment nor an industrial reprocessing plant exists in the Federal Republic of Germany. Transports are therefore carried out according to international standards, such as the IAEA recommendations laid down in legal traffic regulations. Control and physical protection are being exercised on the basis of national regulations. The paper summarizes the experience gained in performing quite a number of various shipments and deals with the application of the relevant transport regulations. It also gives a brief outlook on future aspects, such as the increasing transport volume, and transport problems related to decommissioning and the operation of a nuclear fuel cycle center

  13. Targeted evidence report : cochlear implants and commercial motor vehicle driver safety : October 29, 2010, revised January 14, 2011.

    Science.gov (United States)

    2011-01-14

    This report was prepared by MANILA Consulting Group, Inc. under Contract No. GS-10F-0177N; Order No. DTMC75-10-F-00013, entitled Medical Programs Research and Analysis Panels Project, with the Department of Transportations Federal Motor Carrier...

  14. 'Motor challenge' pilot programme; Motor Challenge Pilotprogramm. Schweizer Teilnahme im SAVE-Programm: pilot actions for motor systems industrial energy use challenge

    Energy Technology Data Exchange (ETDEWEB)

    Nipkow, J.

    2003-07-01

    This final report for the Swiss Federal Office of Energy (SFOE) presents the results of a pilot project associated with the Motor Challenge Programme (MCP) initiated by the European Commission (Transport and Energy Committee). The programme is briefly described, which aims to improve the efficiency of electrical motors used in industrial compressed-air, pump and ventilator systems as well as in comprehensive motor driven systems. Switzerland's participation in this pilot project is examined, which was concluded after a period of two years when the Motor Challenge Programme itself was launched in February 2003. The mechanisms of the programme are described, whereby companies may become involved in the programme either as partners (users of drive systems) or as endorsers (suppliers, planners, etc., of such systems). Experience gained with two companies in Switzerland - a food processing group and a major chemical pulp producer - who participated in the programme is presented. Efficiency potentials of around 3 GWh/a were identified; these represent a high proportion of the estimated total of 18 GWh/a in the overall programme. A follow-up project is proposed that is to provide detailed information and initiate further efficiency projects in order to encourage other companies to participate in the MCP programme.

  15. 49 CFR 567.4 - Requirements for manufacturers of motor vehicles.

    Science.gov (United States)

    2010-10-01

    ... applicable Federal motor vehicle safety, bumper, and theft prevention standards in effect on the date of... statement: “This vehicle conforms to all applicable Federal motor vehicle safety and theft prevention... conforms to the applicable Federal motor vehicle theft prevention standard in effect on the date of...

  16. Targeted evidence report : cochlear implants and commercial motor vehicle driver safety : draft, October 29, 2010, revised January 14, 2011.

    Science.gov (United States)

    2011-01-14

    This report was prepared by MANILA Consulting Group, Inc. under Contract No. GS-10F-0177N; Order No. DTMC75-10-F-00013, entitled Medical Programs Research and Analysis Panels Project, with the Department of Transportations Federal Motor Carrier...

  17. General Approaches and Requirements on Safety and Security of Radioactive Materials Transport in Russian Federation

    International Nuclear Information System (INIS)

    Ershov, V.N.; Buchel'nikov, A.E.; Komarov, S.V.

    2016-01-01

    Development and implementation of safety and security requirements for transport of radioactive materials in the Russian Federation are addressed. At the outset it is worth noting that the transport safety requirements implemented are in full accordance with the IAEA's ''Regulations for the Safe Transport of Radioactive Material (2009 Edition)''. However, with respect to security requirements for radioactive material transport in some cases the Russian Federation requirements for nuclear material are more stringent compared to IAEA recommendations. The fundamental principles of safety and security of RM managements, recommended by IAEA documents (publications No. SF-1 and GOV/41/2001) are compared. Its correlation and differences concerning transport matters, the current level and the possibility of harmonization are analysed. In addition a reflection of the general approaches and concrete transport requirements is being evaluated. Problems of compliance assessment, including administrative and state control problems for safety and security provided at internal and international shipments are considered and compared. (author)

  18. 48 CFR 908.7101 - Motor vehicles.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Motor vehicles. 908.7101 Section 908.7101 Federal Acquisition Regulations System DEPARTMENT OF ENERGY COMPETITION ACQUISITION PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES Acquisition of Special Items 908.7101 Motor vehicles. ...

  19. 76 FR 38267 - The Federal Motor Carrier Safety Administration's 2011-2016 Strategic Plan: Raising the Safety Bar

    Science.gov (United States)

    2011-06-29

    ... Federal Docket Management System (FDMS) address: http://www.regulations.gov . Fax: 202-493-2251. Mail: Docket Management Facility (M-30), U.S. Department of Transportation, West Building Ground Floor, Room... transport and logistics supply chain in improving CMV safety factors. This is a holistic view of safety that...

  20. Developing a Rubric and Best Practices for Conducting Counts of Non-Motorized Transportation Users

    Science.gov (United States)

    2016-01-01

    Over the past five years non-motorized modes of transportation have become ever more prevalent on Utahs roadways. Historically, these modes have not been included in traffic counts nor are they accurately represented in the long range planning mod...

  1. 75 FR 24434 - Federal Travel Regulation (FTR); Transportation in Conjunction With Official Travel and Relocation

    Science.gov (United States)

    2010-05-05

    ...-0010, sequence 1] RIN 3090-AJ02 Federal Travel Regulation (FTR); Transportation in Conjunction With Official Travel and Relocation AGENCY: Office of Governmentwide Policy, General Services Administration (GSA). ACTION: Final rule. SUMMARY: This final rule amends the Federal Travel Regulation (FTR), by...

  2. 75 FR 59105 - Procedures for Transportation Workplace Drug and Alcohol Testing Programs: Federal Drug Testing...

    Science.gov (United States)

    2010-09-27

    ... 2105-AE03 Procedures for Transportation Workplace Drug and Alcohol Testing Programs: Federal Drug... the Federal workplace drug testing program but also pointed out that ``* * * the Department of.... Executive Order 12866 and Regulatory Flexibility Act This Interim Final Rule is not significant for purposes...

  3. Quantitative measurements and modeling of cargo–motor interactions during fast transport in the living axon

    International Nuclear Information System (INIS)

    Seamster, Pamela E; Loewenberg, Michael; Pascal, Jennifer; Chauviere, Arnaud; Gonzales, Aaron; Cristini, Vittorio; Bearer, Elaine L

    2012-01-01

    The kinesins have long been known to drive microtubule-based transport of sub-cellular components, yet the mechanisms of their attachment to cargo remain a mystery. Several different cargo-receptors have been proposed based on their in vitro binding affinities to kinesin-1. Only two of these—phosphatidyl inositol, a negatively charged lipid, and the carboxyl terminus of the amyloid precursor protein (APP-C), a trans-membrane protein—have been reported to mediate motility in living systems. A major question is how these many different cargo, receptors and motors interact to produce the complex choreography of vesicular transport within living cells. Here we describe an experimental assay that identifies cargo–motor receptors by their ability to recruit active motors and drive transport of exogenous cargo towards the synapse in living axons. Cargo is engineered by derivatizing the surface of polystyrene fluorescent nanospheres (100 nm diameter) with charged residues or with synthetic peptides derived from candidate motor receptor proteins, all designed to display a terminal COOH group. After injection into the squid giant axon, particle movements are imaged by laser-scanning confocal time-lapse microscopy. In this report we compare the motility of negatively charged beads with APP-C beads in the presence of glycine-conjugated non-motile beads using new strategies to measure bead movements. The ensuing quantitative analysis of time-lapse digital sequences reveals detailed information about bead movements: instantaneous and maximum velocities, run lengths, pause frequencies and pause durations. These measurements provide parameters for a mathematical model that predicts the spatiotemporal evolution of distribution of the two different types of bead cargo in the axon. The results reveal that negatively charged beads differ from APP-C beads in velocity and dispersion, and predict that at long time points APP-C will achieve greater progress towards the presynaptic

  4. 49 CFR 392.16 - Use of seat belts.

    Science.gov (United States)

    2010-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS DRIVING OF COMMERCIAL MOTOR VEHICLES Driving of Commercial Motor Vehicles § 392.16 Use of seat belts. A commercial motor vehicle which...

  5. Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons.

    Directory of Open Access Journals (Sweden)

    Laura Restani

    2012-12-01

    Full Text Available The striking differences between the clinical symptoms of tetanus and botulism have been ascribed to the different fate of the parental neurotoxins once internalised in motor neurons. Tetanus toxin (TeNT is known to undergo transcytosis into inhibitory interneurons and block the release of inhibitory neurotransmitters in the spinal cord, causing a spastic paralysis. In contrast, botulinum neurotoxins (BoNTs block acetylcholine release at the neuromuscular junction, therefore inducing a flaccid paralysis. Whilst overt experimental evidence supports the sorting of TeNT to the axonal retrograde transport pathway, recent findings challenge the established view that BoNT trafficking is restricted to the neuromuscular junction by highlighting central effects caused by these neurotoxins. These results suggest a more complex scenario whereby BoNTs also engage long-range trafficking mechanisms. However, the intracellular pathways underlying this process remain unclear. We sought to fill this gap by using primary motor neurons either in mass culture or differentiated in microfluidic devices to directly monitor the endocytosis and axonal transport of full length BoNT/A and BoNT/E and their recombinant binding fragments. We show that BoNT/A and BoNT/E are internalised by spinal cord motor neurons and undergo fast axonal retrograde transport. BoNT/A and BoNT/E are internalised in non-acidic axonal carriers that partially overlap with those containing TeNT, following a process that is largely independent of stimulated synaptic vesicle endo-exocytosis. Following intramuscular injection in vivo, BoNT/A and TeNT displayed central effects with a similar time course. Central actions paralleled the peripheral spastic paralysis for TeNT, but lagged behind the onset of flaccid paralysis for BoNT/A. These results suggest that the fast axonal retrograde transport compartment is composed of multifunctional trafficking organelles orchestrating the simultaneous transfer

  6. Legal precedents regarding use and defensibility of risk assessment in Federal transportation of SNF and HLW

    International Nuclear Information System (INIS)

    Bentz, E.J. Jr.; Bentz, C.B.; O'Hora, T.D.; Chen, S.Y.

    1997-01-01

    Risk assessment has become an increasingly important and essential tool in support of Federal decision-making regarding the handling, storage, disposal, and transportation of spent nuclear fuel (SNF) and high-level radioactive waste (HLW). This paper analyzes the current statutory and regulatory framework and related legal precedents with regard to SNF and HLW transportation. The authors identify key scientific and technical issues regarding the use and defensibility of risk assessment in Federal decision-making regarding anticipated shipments

  7. 77 FR 48460 - Transportation of Household Goods in Interstate Commerce; Consumer Protection Regulations

    Science.gov (United States)

    2012-08-14

    ..., direct final rule concerning household goods consumer protection. The direct final rule amended the... No. FMCSA-2012-0119] RIN 2126-AB52 Transportation of Household Goods in Interstate Commerce; Consumer Protection Regulations AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Direct final...

  8. Mathematical interpretation of Brownian motor model: Limit cycles and directed transport phenomena

    Science.gov (United States)

    Yang, Jianqiang; Ma, Hong; Zhong, Suchuang

    2018-03-01

    In this article, we first suggest that the attractor of Brownian motor model is one of the reasons for the directed transport phenomenon of Brownian particle. We take the classical Smoluchowski-Feynman (SF) ratchet model as an example to investigate the relationship between limit cycles and directed transport phenomenon of the Brownian particle. We study the existence and variation rule of limit cycles of SF ratchet model at changing parameters through mathematical methods. The influences of these parameters on the directed transport phenomenon of a Brownian particle are then analyzed through numerical simulations. Reasonable mathematical explanations for the directed transport phenomenon of Brownian particle in SF ratchet model are also formulated on the basis of the existence and variation rule of the limit cycles and numerical simulations. These mathematical explanations provide a theoretical basis for applying these theories in physics, biology, chemistry, and engineering.

  9. 49 CFR 392.12-392.13 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS DRIVING OF COMMERCIAL MOTOR VEHICLES Driving of Commercial Motor Vehicles §§ 392.12-392.13 [Reserved] ...

  10. Federal, state, and local regulation of radioactive-waste transportation: Progress toward a definition of regulatory authority

    International Nuclear Information System (INIS)

    Livingston-Behan, E.A.

    1986-01-01

    The supremacy clause, the commerce clause, and the equal-protection guarantees of the U.S. Constitution establish the basic framework for defining the authority of Federal, State, and local governments to regulate the transportation of radioactive waste. Court decisions and advisory rulings of the U.S. Department of Transportation (DOT) suggest that State and local regulation of the transportation of spent nuclear fuel and high-level radioactive waste is precluded under supremacy-clause principles to the extent that such regulation addresses nuclear safety or aspects of transportation that are already specifically regulated by the Federal government. Even where State and local requirements are found to be valid under the supremacy clause, they must still satisfy constitutional requirements under the commerce and equal-protection clauses. Despite stringent standards of review, State and local transportation requirements have been upheld where directly related to the traditional exercise of police powers in the area of transportation. Legitimate State and local police-power activities identified to date by the DOT and the courts include inspection and enforcement, immediate accident reporting, local regulation of traffic, and certain time-of-day curfews. The extent to which State and local permitting requirements and license fees may be determined valid by the DOT and the courts remains unclear. Continued clarification by the DOT and the courts as to the validity of permits and fees will serve to further define the appropriate balance for Federal, State, and local regulation of radioactive-waste transportation

  11. Models of expert assessments and their study in problems of choice and decision-making in management of motor transport processes

    Science.gov (United States)

    Belokurov, V. P.; Belokurov, S. V.; Korablev, R. A.; Shtepa, A. A.

    2018-05-01

    The article deals with decision making concerning transport tasks on search iterations in the management of motor transport processes. An optimal selection of the best option for specific situations is suggested in the management of complex multi-criteria transport processes.

  12. Upgrades for truck transportation of SNM in the Russian Federation

    International Nuclear Information System (INIS)

    Gardner, B.H.; Kornilovich, E.

    1998-01-01

    The goal of this project is the rapid reduction of risk to truck transportation of SNM in Russia. Enhanced protection is being accomplished by cooperation between the US Department of Energy, MINATOM of Russia, the Russian Ministry of Defense, and various Russian Institutes. This program provides an integrated program of specialized trucks that are equipped with hardened overpack (SNM vault) containers, alarm and communications systems, and armored cabs. Armored escort vehicles are also provided to increase the survivability of the guards escorting convoys. Only indigenous Russian equipment, modified and/or manufactured by Designing Bureau for Motor Vehicle Transport Equipment (KBATO), is provided under this program. The US will not provide assistance in the truck transportation arena without a commitment from the Russian facility to provide heavily armed escorts for SNM movement. Each site conducts a detailed transportation needs assessment study that is used as the basis for prioritizing assistance. The Siberian Chemical Combine (Tomsk-7) was the initial site of cooperation. The designs used at Tomsk-7 are serving as the baseline for all future vehicles modified under this program. In FY98, many vehicles systems have been ordered for various institutes. Many additional systems will be ordered in FY99

  13. Win-Win transportation solutions price reforms with multiple benefits

    International Nuclear Information System (INIS)

    Litman, T.

    2001-01-01

    Reform strategies in the transportation market, such as the Win-Win Transportation Solutions, can provide several economic, social and environmental benefits. The strategies are cost effective, technically feasible reforms based on market principles which help create a more equitable and efficient transportation system that supports sustainable economic development. The benefits they provide include reduced traffic congestion, road and parking facility savings, consumer savings, equity, safety and environmental protection. They also increase economic productivity. If fully implemented, they could reduce motor vehicle impacts by 15 to 30 per cent and could help achieve the Kyoto emission reduction targets. Examples of Win-Win strategies at the federal level include: (1) removal of subsidies to oil production and internalized costs, and (2) tax exempt employer provided transfer benefits. Examples of Win-Win strategies at the state/provincial level include: (1) distance-based vehicle insurance and registration fees, (2) least-coast transportation planning and funding, (3) revenue-neutral tax shifting, (4) road pricing, (5) reform motor carrier regulations for competition and efficiency, (6) local and regional transportation demand management programs, (7) more efficient land use, (8) more flexible zoning requirements, (9) parking cash out, (10) transportation management associations, (11) location-efficient housing and mortgages, (12) school and campus trip management, (13) car sharing, (14) non-motorized transport improvements, and (15) traffic calming. It was noted that any market reform that leads to more efficient use of existing transportation systems can provide better economic development benefits. 9 refs., 1 tab., 1 fig

  14. 48 CFR 970.2307-1 - Motor vehicle fleet operations.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Motor vehicle fleet..., Renewable Energy Technologies, Occupational Safety and Drug-Free Work Place 970.2307-1 Motor vehicle fleet... that the Federal motor vehicle fleet will serve as an example and provide a leadership role in the...

  15. Motor fuel prices in Turkey

    International Nuclear Information System (INIS)

    Erdogdu, Erkan

    2014-01-01

    The world's most expensive motor fuel (gasoline, diesel and LPG) is sold most likely in the Republic of Turkey. This paper investigates the key issues related to the motor fuel prices in Turkey. First of all, the paper analyses the main reason behind high prices, namely motor fuel taxes in Turkey. Then, it estimates the elasticity of motor fuel demand in Turkey using an econometric analysis. The findings indicate that motor fuel demand in Turkey is quite inelastic and, therefore, not responsive to price increases caused by an increase in either pre-tax prices or taxes. Therefore, fuel market in Turkey is open to opportunistic behavior by firms (through excessive profits) and the government (through excessive taxes). Besides, the paper focuses on the impact of high motor fuel prices on road transport associated activities, including the pattern of passenger transportation, motorization rate, fuel use, total kilometers traveled and CO 2 emissions from road transportation. The impact of motor fuel prices on income distribution in Turkey and Turkish public opinion about high motor fuel prices are also among the subjects investigated in the course of the study. - Highlights: • The key issues (e.g. taxes) related to motor fuel prices in Turkey are explored. • Their impact on transport activities and income distribution is also investigated. • An econometric analysis is performed to estimate motor fuel demand in Turkey. • Motor fuel demand in Turkey is found to be quite inelastic. • Turkish fuel market is open to opportunistic behavior by firms and the government

  16. 75 FR 55711 - Federal Implementation Plans To Reduce Interstate Transport of Fine Particulate Matter and Ozone...

    Science.gov (United States)

    2010-09-14

    ...: (919) 541-0824; e-mail address: [email protected] . SUPPLEMENTARY INFORMATION: The proposed Transport... (i.e., section V.D.4.a (75 FR 45307-9)) that discusses in detail the proposed Transport Rule trading...-9201-6] RIN 2060-AP50 Federal Implementation Plans To Reduce Interstate Transport of Fine Particulate...

  17. Small-sized linear accelerator of 2.5 MeV electrons with a local radiation shield for custom examination of freight transported by motor transport

    International Nuclear Information System (INIS)

    Baklanov, A.V.; Gavrish, Yu.N.; Klinov, A.P.; Krest'yaninov, A.S.; Nikolaev, V.M.; Fomin, L.P.; Linkenbach, H.A.; Geus, G.; Knospel, W.

    2001-01-01

    A new development of a small-sized linear accelerator of 2.5 MeV electrons with a local radiation protection is described. The accelerator is intended for movable facilities of radiation custom of the freight transported by motor transport. Main constructive solutions, mass and dimension characteristics and results of preliminary tests of the accelerator parameters and characteristics of radiation protection are presented [ru

  18. Scintigraphic quantitation of gastrointestinal motor activity and transport: Oesophagus and stomach

    International Nuclear Information System (INIS)

    Stacher, G.; Bergmann, H.

    1992-01-01

    For the recognition and characterisation of oesophageal motor disorders, manometry represents the most reliable tool but yields no information on bolus transport. The transport can be quantitated by radionuclide techniques. The patient is positioned supine beneath a gamma-camera and instructed to swallow a radiolabelled bolus in a single gulp. Using a marker over the cricoid and the activity in the stomach as landmarks, regions of interest are drawn representing the upper, middle and lower third of the oesophagus and the gastric fundus. Activity-time curves enable one to recognise the clearance patterns in these regions. In combination, manometric and radionuclide transit studies recognise a higher number of motor disorders than either procedure alone. Radionuclide methods also are the most reliable and sensitive to quantitate gastric emptying. Procedure, meal size and composition as well as patient position must be standardised and correction techniques applied. The emptying of solid and liquid meal constituents can be evaluated concomitantly. Solids start to empty only after a lag phase of varying extent. With semi-solid meals, which are emptied at the same rate as solid meals of identical composition in the postlag phase, the recording time can be considerably shorter. Besides gastric emptying, the amplitude, frequency and propagation velocity of antral contractions can be recorded using serial images of short frame time and specially devised analytic techniques. (orig.)

  19. Scintigraphic quantitation of gastrointestinal motor activity and transport: Oesophagus and stomach

    Energy Technology Data Exchange (ETDEWEB)

    Stacher, G.; Bergmann, H. (Vienna Univ. (Austria). Psychiatrische Klinik Vienna Univ. (Austria). 1. Chirurgische Klinik Ludwig-Boltzmann-Institut fuer Nuklearmedizin, Vienna (Austria))

    1992-09-01

    For the recognition and characterisation of oesophageal motor disorders, manometry represents the most reliable tool but yields no information on bolus transport. The transport can be quantitated by radionuclide techniques. The patient is positioned supine beneath a gamma-camera and instructed to swallow a radiolabelled bolus in a single gulp. Using a marker over the cricoid and the activity in the stomach as landmarks, regions of interest are drawn representing the upper, middle and lower third of the oesophagus and the gastric fundus. Activity-time curves enable one to recognise the clearance patterns in these regions. In combination, manometric and radionuclide transit studies recognise a higher number of motor disorders than either procedure alone. Radionuclide methods also are the most reliable and sensitive to quantitate gastric emptying. Procedure, meal size and composition as well as patient position must be standardised and correction techniques applied. The emptying of solid and liquid meal constituents can be evaluated concomitantly. Solids start to empty only after a lag phase of varying extent. With semi-solid meals, which are emptied at the same rate as solid meals of identical composition in the postlag phase, the recording time can be considerably shorter. Besides gastric emptying, the amplitude, frequency and propagation velocity of antral contractions can be recorded using serial images of short frame time and specially devised analytic techniques. (orig.).

  20. 49 CFR 399.201 - Purpose and scope.

    Science.gov (United States)

    2010-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS EMPLOYEE SAFETY AND HEALTH... requirements are intended to enhance the safety of motor carrier employees. ...

  1. Federal and state regulatory schemes affecting liability for high-level waste transportation incidents: opportunities for clarification and amendment

    International Nuclear Information System (INIS)

    Friel, L.E.; Livingston-Behan, E.A.

    1985-01-01

    The Price-Anderson Act of 1957 provides extensive public liability coverage in the event of a serious accident involving the transportation of nuclear materials to or from certain federally-licensed, or federal contractor-operated facilities. While actual liability for a nuclear incident and the extent of damages are usually determined by state law, the Act establishes a comprehensive system for the payment of such damages. Despite the federally-mandated scheme for liability coverage several aspects of the Act's application to transportation to a permanent repository have not yet been settled and are open to various interpretations. Some areas of uncertainty apply not only to future waste transport to a repository, but also to current transportation activities, and include: coverage for emergency response and clean-up costs; coverage for precautionary evacuations; and the federal government's financial liability. The need to address liability issues is also increasingly recognized at the state level. The state laws which are used to determine liability and the extent of damages in the event of a transportation accident vary widely among states and significantly affect the compensation that an injured person will receive under the provisions of the Price-Anderson Act. Areas of state law deserving special attention include: standards for determining liability; statutes of limitations; standards for proof of causation; state sovereign immunity statutes; and recovery of unique emergency response costs

  2. 49 CFR 392.15 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS DRIVING OF COMMERCIAL MOTOR VEHICLES Driving of Commercial Motor Vehicles § 392.15 [Reserved] ...

  3. 49 CFR 392.18 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS DRIVING OF COMMERCIAL MOTOR VEHICLES Driving of Commercial Motor Vehicles § 392.18 [Reserved] ...

  4. The Federal Air Pollution Program.

    Science.gov (United States)

    National Air Pollution Control Administration (DHEW), Washington, DC.

    Described is the Federal air pollution program as it was in 1967. The booklet is divided into these major topics: History of the Federal Program; Research; Assistance to State and Local Governments; Abatement and Prevention of Air Pollution; Control of Motor Vehicle Pollution; Information and Education; and Conclusion. Federal legislation has…

  5. Transportation Security : federal action needed to enhance security efforts : statement of Peter Guerrero, Director, Physical Infrastructure Issues

    Science.gov (United States)

    2003-09-09

    Mr. Guerrero's testimony examines (1) challenges in securing the nation's transportation system; (2) actions transportation operators, as well as state and local governments, have taken since September 11 to enhance security; (3) the federal role in ...

  6. 49 CFR 372.103 - Motor vehicles employed solely in transporting school children and teachers to or from school.

    Science.gov (United States)

    2010-10-01

    ... school children and teachers to or from school. 372.103 Section 372.103 Transportation Other Regulations... Exemptions § 372.103 Motor vehicles employed solely in transporting school children and teachers to or from school. The exemption set forth in 49 U.S.C. 13506(a)(1) shall not be construed as being inapplicable to...

  7. Experimental measurement of efficiency and transport coherence of a cold-atom Brownian motor in optical lattices.

    Science.gov (United States)

    Zelan, M; Hagman, H; Labaigt, G; Jonsell, S; Dion, C M

    2011-02-01

    The rectification of noise into directed movement or useful energy is utilized by many different systems. The peculiar nature of the energy source and conceptual differences between such Brownian motor systems makes a characterization of the performance far from straightforward. In this work, where the Brownian motor consists of atoms interacting with dissipative optical lattices, we adopt existing theory and present experimental measurements for both the efficiency and the transport coherence. We achieve up to 0.3% for the efficiency and 0.01 for the Péclet number.

  8. Road transport of LWR spent fuel in the Federal Republic of Germany

    International Nuclear Information System (INIS)

    Bach, R.

    1987-01-01

    Since 1967, when fuel from LWRs was first transported by road from the Kahl reactor in the Federal Republic of Germany to the Eurochemic reprocessing plant in Belgium, a total of more than 400 road transports have been performed without any adverse effect on the environment. In the beginning, road transport was the dominant mode. However, in recent years large capacity rail flasks with a weight ranging from 80 to 110 tonnes have been put into service in order to cope with the increasing demand of transport services and to replace existing smaller flasks designed primarily for road transport. Therefore, the number of spent fuel transports by road has declined. However, road transport of heavy flasks from reactor sites without a direct rail link to a nearby rail terminal has become an important task and a number of special problems have had to be solved. The following items are discussed, with special emphasis placed on heavy load transports by road from the reactor to a nearby rail terminal: design of road transport equipment to meet the requirements of the national traffic law; application of technical and administrative procedures to meet the IAEA Regulations; transport restrictions due to overload/oversize; transfer of the flask from the reactor to the transport vehicle; handling of the flask at the rail terminal; turn-around inspection and periodic maintenance of equipment to ensure safe performance of transport; and physical protection during transport and handling at rail terminals. (author). 4 figs

  9. 75 FR 54388 - General Motors Company Formerly Known as General Motors Corporation, Orion Assembly Plant...

    Science.gov (United States)

    2010-09-07

    ... Formerly Known as General Motors Corporation, Orion Assembly Plant Including On-Site Leased Workers From Aerotek Automotive Lake Orion, MI; Amended Certification Regarding Eligibility To Apply for Worker... Motors Corporation, Orion Assembly Plant, Lake Orion, Michigan. The notice was published in the Federal...

  10. Regulation of motor proteins, axonal transport deficits and adult-onset neurodegenerative diseases.

    Science.gov (United States)

    Brady, Scott T; Morfini, Gerardo A

    2017-09-01

    Neurons affected in a wide variety of unrelated adult-onset neurodegenerative diseases (AONDs) typically exhibit a "dying back" pattern of degeneration, which is characterized by early deficits in synaptic function and neuritic pathology long before neuronal cell death. Consistent with this observation, multiple unrelated AONDs including Alzheimer's disease, Parkinson's disease, Huntington's disease, and several motor neuron diseases feature early alterations in kinase-based signaling pathways associated with deficits in axonal transport (AT), a complex cellular process involving multiple intracellular trafficking events powered by microtubule-based motor proteins. These pathogenic events have important therapeutic implications, suggesting that a focus on preservation of neuronal connections may be more effective to treat AONDs than addressing neuronal cell death. While the molecular mechanisms underlying AT abnormalities in AONDs are still being analyzed, evidence has accumulated linking those to a well-established pathological hallmark of multiple AONDs: altered patterns of neuronal protein phosphorylation. Here, we present a short overview on the biochemical heterogeneity of major motor proteins for AT, their regulation by protein kinases, and evidence revealing cell type-specific AT specializations. When considered together, these findings may help explain how independent pathogenic pathways can affect AT differentially in the context of each AOND. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Ohio Department of Transportation State Infrastructure Bank Annual Financial Report : Federal Fiscal Year 2009

    Science.gov (United States)

    2009-01-01

    The Ohio Department of Transportation is pleased to present the Federal : Fiscal Year (FFY) 2009 State Infrastructure Bank (SIB) Annual Financial : Report. : The portfolio of the FFY 2009 SIB had a total of nine loans totaling $9.0 : million and one ...

  12. Review of Federal Motor Vehicle Safety Standards (FMVSS) for Automated Vehicles : Identifying Potential Barriers and Challenges for the Certification of Automated Vehicles Using Existing FMVSS

    Science.gov (United States)

    2016-03-11

    The purpose of this work is to identify instances where the existing Federal Motor Vehicle Safety Standards may pose challenges to the introduction of automated vehicles. It identifies standards requiring further review - both to ensure that existing...

  13. 78 FR 9771 - Federal Highway Administration

    Science.gov (United States)

    2013-02-11

    ... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Notice of Final Federal Agency Action on Proposed Transportation Project in Illinois and Indiana AGENCY: Federal Highway Administration...., Acting Division Administrator, Federal Highway Administration, 3250 Executive Park Drive, Springfield...

  14. Ohio Department of Transportation State Infrastructure Bank Annual Financial Report : Federal Fiscal Year 2004

    Science.gov (United States)

    2004-01-01

    The Ohio Department of Transportation is pleased to present the Federal Fiscal : Year 2004 State Infrastructure Bank (SIB) Annual Financial Report. The portfolio of : the FFY 04 SIB had a total of nineteen loans in the amount of $47,340,891. : A comp...

  15. Ohio Department of Transportation State Infrastructure Bank Annual Financial Report : Federal Fiscal Year 2008

    Science.gov (United States)

    2008-01-01

    The Ohio Department of Transportation is pleased to present the Federal Fiscal Year (FFY) 2008 State Infrastructure Bank (SIB) Annual Financial Report. The portfolio of the FFY 2008 SIB had a total of five loans totaling $22.1 million. Since the begi...

  16. Ohio Department of Transportation State Infrastructure Bank Annual Financial Report : Federal Fiscal Year 2007

    Science.gov (United States)

    2007-01-01

    The Ohio Department of Transportation is pleased to present the Federal : Fiscal Year (FFY) 2007 State Infrastructure Bank (SIB) Annual Financial : Report. : The portfolio of the FFY 2007 SIB had a total of 13 loans and 1 bond in the : amount of $17....

  17. 41 CFR 101-25.402 - Motor vehicles.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Motor vehicles. 101-25.402 Section 101-25.402 Public Contracts and Property Management Federal Property Management... Standards § 101-25.402 Motor vehicles. Replacement of motor vehicles shall be in accordance with the...

  18. 49 CFR 372.225 - Lexington-Fayette Urban County, KY.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Lexington-Fayette Urban County, KY. 372.225 Section 372.225 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS...

  19. Improving commercial motor vehicle safety in Oregon.

    Science.gov (United States)

    2010-08-01

    This study addressed the primary functions of the Oregon Department of Transportations (ODOTs) Motor Carrier Safety Assistance Program (MCSAP), which is administered by the Motor Carrier Transportation Division (MCTD). The study first documente...

  20. Importance of anisotropy in detachment rates for force production and cargo transport by a team of motor proteins.

    Science.gov (United States)

    Takshak, Anjneya; Kunwar, Ambarish

    2016-05-01

    Many cellular processes are driven by collective forces generated by a team consisting of multiple molecular motor proteins. One aspect that has received less attention is the detachment rate of molecular motors under mechanical force/load. While detachment rate of kinesin motors measured under backward force increases rapidly for forces beyond stall-force; this scenario is just reversed for non-yeast dynein motors where detachment rate from microtubule decreases, exhibiting a catch-bond type behavior. It has been shown recently that yeast dynein responds anisotropically to applied load, i.e. detachment rates are different under forward and backward pulling. Here, we use computational modeling to show that these anisotropic detachment rates might help yeast dynein motors to improve their collective force generation in the absence of catch-bond behavior. We further show that the travel distance of cargos would be longer if detachment rates are anisotropic. Our results suggest that anisotropic detachment rates could be an alternative strategy for motors to improve the transport properties and force production by the team. © 2016 The Protein Society.

  1. 49 CFR 371.13 - Accounting.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Accounting. 371.13 Section 371.13 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS BROKERS OF PROPERTY § 371.13 Accounting...

  2. Comparison of adult physical activity levels in three Swiss alpine communities with varying access to motorized transportation.

    Science.gov (United States)

    Dombois, Oliver Thommen; Braun-Fahrländer, Charlotte; Martin-Diener, Eva

    2007-09-01

    To compare physical activity levels of residents of three Swiss alpine communities with varying access to motorized transport and to investigate whether socio-demographic factors, the settlement structure or means of transport affect these levels. Between January and February 2004 a computer assisted telephone interview was conducted with 901 randomly selected adults aged 18 years or older living in three Swiss alpine communities. In particular, information on moderate and vigorous intensity physical activities and on transport behaviour was collected. Respondents were categorized as 'sufficiently active' or 'insufficiently active' according to self-reported physical activity. People living in community 1 without access to motorized traffic were significantly more likely to be sufficiently active (Sex- and age-adjusted prevalences of sufficient total physical activity, 43.9% 95% CI: 38.3%-49.8%) compared to individuals living in the other two communities (community 2: 35.9%, 95% CI: 30.6%-41.6%, community 3: 32.7%, 95% CI: 27.5%-38.3%). The differences were due to higher levels of moderate physical activities. Vigorous physical activity levels did not differ between the communities. Community differences were explained by passive means of transport to work and for leisure time activities. Although the environment encountered in the three alpine communities is generally conducive to physical activity the majority of the participants did not achieve recommended activity levels. Passive mode of transport to work and during leisure time was strongly associated with insufficient total physical activity. Walking and cycling for transportation is thus a promising approach to promote health enhancing physical activity.

  3. 48 CFR 945.570-8 - Reporting motor vehicle data.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Reporting motor vehicle... Reporting motor vehicle data. (a) Contractors conducting motor vehicle operations shall forward annually (on or before December 1) to the contracting officer their plan for acquisition of motor vehicles for the...

  4. 49 CFR 375.207 - What items must be in my advertisements?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false What items must be in my advertisements? 375.207 Section 375.207 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS TRANSPORTATION OF HOUSEHOLD GOODS IN INTERSTATE...

  5. 49 CFR 397.13 - Smoking.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Smoking. 397.13 Section 397.13 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS TRANSPORTATION OF HAZARDOUS MATERIALS; DRIVING AND PARKING RULES General § 397.13...

  6. TRANSPORTATION INDUSTRY EFFECTIVE MANAGEMENT CONDITIONS

    Directory of Open Access Journals (Sweden)

    V. I. Kuznetsov

    2011-01-01

    Full Text Available Main aspects that determine conditions of transportation industry effective management and decrease of transportation expenses are discussed. Theoretical concepts making it possible to solve the problem of scientific management of the whole country’s goods transportation costs are provided for. Main approaches are presented to the solution of motor transport operation ecological optimization problem as well as to the rise of motor transport workers’ labor productivity, to the increase of transportation vehicles use efficiency and to determine functional capacity of the motor transport complex.

  7. 48 CFR 908.7101-4 - Replacement of motor vehicles.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Replacement of motor....7101-4 Replacement of motor vehicles. (a) The replacement of motor vehicles shall be in accordance with... Heads of Contracting Activities may arrange to sell, as exchange sales, used motor vehicles being...

  8. Energy-saving motor; Energiesparmotor

    Energy Technology Data Exchange (ETDEWEB)

    Lindegger, M.

    2002-07-01

    This report for the Swiss Federal Office of Energy (SFOE) describes the development and testing of an advanced electrical motor using a permanent-magnet rotor. The aims of the project - to study the technical feasibility and market potential of the Eco-Motor - are discussed and the three phases of the project described. These include the calculation and realisation of a 250-watt prototype operating at 230 V, the measurement of the motor's characteristics as well as those of a comparable asynchronous motor on the test bed at the University of Applied Science in Lucerne, Switzerland, and a market study to establish if the Eco-Motor and its controller can compete against normal asynchronous motors. Also, the results of an analysis of the energy-savings potential is made, should such Eco-Motors be used. Detailed results of the three phases of the project are presented and the prospects of producing such motors in Switzerland for home use as well as for export are examined.

  9. 49 CFR 385.107 - The safety audit.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false The safety audit. 385.107 Section 385.107 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS SAFETY FITNESS PROCEDURES Safety Monitoring System for Mexico-Domicile...

  10. 76 FR 42163 - Pilot Program on the North American Free Trade Agreement (NAFTA) Long-Haul Trucking Provisions...

    Science.gov (United States)

    2011-07-18

    ...; Correction AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice; correction. SUMMARY: The Federal Motor Carrier Safety Administration published a document in the Federal Register of... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2011...

  11. 78 FR 17282 - Agency Information Collection Activities; Approval of a Currently Approved Information Collection...

    Science.gov (United States)

    2013-03-20

    ...; Correction AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice; correction. SUMMARY: The Federal Motor Carrier Safety Administration published a document in the Federal Register of... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2012...

  12. 48 CFR 945.570-7 - Disposition of motor vehicles.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Disposition of motor... Disposition of motor vehicles. (a) The contractor shall dispose of DOE-owned motor vehicles as directed by the contracting officer. (b) DOE-owned motor vehicles may be disposed of as exchange/sale items when directed by...

  13. Principais fatores associados à ocorrência de acidentes de trânsito na BR 163, Mato Grosso, Brasil, 2004 Main factors associated with motor vehicle accidents on Federal Highway 163, Mato Grosso State, Brazil, 2004

    Directory of Open Access Journals (Sweden)

    Lívia Victório de Carvalho Almeida

    2009-02-01

    Full Text Available O transporte é essencial para o desenvolvimento econômico de Mato Grosso, Brasil, sendo a BR 163 a principal rodovia de escoamento da produção agropecuária da região. Uma das conseqüências desta atividade é a ocorrência de acidentes de trânsito. Com o objetivo de analisar e categorizar os principais fatores associados à ocorrência de acidentes nesta rodovia, foram utilizados dados da Superintendência de Polícia Rodoviária Federal referentes ao ano de 2004. Nos resultados, destacaram-se como fatores associados à maior chance de ocorrência de acidentes com vítimas (com significância estatística: a condição de rolamento regular (OR = 1,89; IC: 1,32-2,70; os acidentes do tipo colisão frontal (OR = 14,14; IC: 8,96-22,32 e atropelamento de pedestre (OR = 35,95; IC: 8,10-159,52; e os fatores contribuintes defeito na via (OR = 4,35; IC: 1,94-9,75 e desobediência à sinalização (OR = 5,69; IC: 2,01-16,12. Conclui-se que para reduzir o problema dos acidentes nesta rodovia é preciso estabelecer medidas de intervenção de caráter global, não focalizando ações somente na modificação do comportamento do condutor e na fiscalização, mas considerando questões regionais e suas dimensões econômicas, sociais e culturais.Transportation is essential to the economic development of Mato Grosso State, Brazil, and Federal Highway 163 is the main route for marketing regional agricultural produce. One unfortunate consequence of this activity is the occurrence of motor vehicle accidents. With the aim of analyzing and categorizing the main factors associated with motor vehicle accidents on this highway, the current study used data from the Mato Grosso State Division of the Brazilian Federal Highway Patrol for the year 2004. Factors significantly associated with accidents involving casualties were: substandard paving (OR = 1.89; CI: 1.32-2.70; front-end collisions (OR = 14.14; CI: 8.96-22.32; and running over pedestrians (OR = 35.95; CI

  14. 49 CFR 571.221 - Standard No. 221, School bus body joint strength.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Standard No. 221, School bus body joint strength. 571.221 Section 571.221 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR VEHICLE SAFETY STANDARDS Federal Motor Vehicle Safety Standard...

  15. Beznau nuclear power plant: comments of the Federal Department of Transport, Communications and Energy on the reproaches of Greenpeace

    International Nuclear Information System (INIS)

    Ogi, A.

    1995-01-01

    Answer of the chairman of the EVED (Federal Department of Transport, Communications and Energy) to the open letter in which Greenpeace Switzerland made massive accusations against the nuclear power plant Beznau and the HSK (Federal Nuclear Safety Inspectorate). All the charges are rebutted in this answer

  16. 78 FR 59082 - Privacy Act of 1974; Department of Transportation, Federal Motor Carrier Safety Administration...

    Science.gov (United States)

    2013-09-25

    ..., [email protected] . For privacy issues please contact: Claire W. Barrett, Departmental Chief... DEPARTMENT OF TRANSPORTATION Office of the Secretary [Docket No. FMCSA-2013-0306] Privacy Act of... Administration (FMCSA), DOT. ACTION: Notice to amend a system of records. SUMMARY: In accordance with the Privacy...

  17. 78 FR 41183 - Federal Aviation Administration

    Science.gov (United States)

    2013-07-09

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Meeting: RTCA Program Management Committee AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION... Operations Group, Federal Aviation Administration. [FR Doc. 2013-16464 Filed 7-8-13; 8:45 am] BILLING CODE...

  18. 49 CFR 173.33 - Hazardous materials in cargo tank motor vehicles.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Hazardous materials in cargo tank motor vehicles... Transportation § 173.33 Hazardous materials in cargo tank motor vehicles. (a) General requirements. (1) No person may offer or accept a hazardous material for transportation in a cargo tank motor vehicle except as...

  19. Motor proteins and molecular motors: how to operate machines at the nanoscale

    International Nuclear Information System (INIS)

    Kolomeisky, Anatoly B

    2013-01-01

    Several classes of biological molecules that transform chemical energy into mechanical work are known as motor proteins or molecular motors. These nanometer-sized machines operate in noisy stochastic isothermal environments, strongly supporting fundamental cellular processes such as the transfer of genetic information, transport, organization and functioning. In the past two decades motor proteins have become a subject of intense research efforts, aimed at uncovering the fundamental principles and mechanisms of molecular motor dynamics. In this review, we critically discuss recent progress in experimental and theoretical studies on motor proteins. Our focus is on analyzing fundamental concepts and ideas that have been utilized to explain the non-equilibrium nature and mechanisms of molecular motors. (topical review)

  20. 49 CFR 389.23 - Consideration of comments received.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Consideration of comments received. 389.23 Section 389.23 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER... PROCEDURES-FEDERAL MOTOR CARRIER SAFETY REGULATIONS Procedures for Adoption of Rules § 389.23 Consideration...

  1. The motorization of peoples' transportation in China. Between economic growth and sustainability; La motorisation du transport de personnes en Chine. Entre croissance economique et soutenabilite

    Energy Technology Data Exchange (ETDEWEB)

    Allaire, J.

    2004-01-01

    This paper aims at presenting the origin of the boom of motorized individual transport in China, its already palpable consequences, and the adaptations of the government. The first part shows how the expansion of the automotive industry has been organized by the government. The second part presents the negative externalities linked with motorization: consumption of the urban space, social costs, local and global environmental costs, geo-strategical risks. Finally, the third part explains how the Chinese decision makers try to reduce the problems generated by the shift from a bicycle civilization to an automobile civilization. (J.S.)

  2. 76 FR 38209 - Meeting of the Department of Justice's (DOJ's) National Motor Vehicle Title Information System...

    Science.gov (United States)

    2011-06-29

    ... Department of Justice's (DOJ's) National Motor Vehicle Title Information System (NMVTIS) Federal Advisory... announcement of a meeting of DOJ's National Motor Vehicle Title Information System (NMVTIS) Federal Advisory... FURTHER INFORMATION CONTACT: Alissa Huntoon, Designated Federal Employee (DFE), Bureau of Justice...

  3. 77 FR 10573 - Meeting of the Department of Justice's (DOJ's) National Motor Vehicle Title Information System...

    Science.gov (United States)

    2012-02-22

    ... Department of Justice's (DOJ's) National Motor Vehicle Title Information System (NMVTIS) Federal Advisory... announcement of a meeting of DOJ's National Motor Vehicle Title Information System (NMVTIS) Federal Advisory.... FOR FURTHER INFORMATION CONTACT: Todd Brighton, Designated Federal Employee (DFE), Bureau of Justice...

  4. 78 FR 51747 - Meeting of the Department of Justice's (DOJ's) National Motor Vehicle Title Information System...

    Science.gov (United States)

    2013-08-21

    ... Department of Justice's (DOJ's) National Motor Vehicle Title Information System (NMVTIS) Federal Advisory... announcement of a meeting of DOJ's National Motor Vehicle Title Information System (NMVTIS) Federal Advisory.... FOR FURTHER INFORMATION CONTACT: Todd Brighton, Designated Federal Employee (DFE), Bureau of Justice...

  5. The potential application of military fleet scheduling tools to the Federal Waste Management System Transportation System

    International Nuclear Information System (INIS)

    Harrison, I.G.; Pope, R.B.; Kraemer, R.D.; Hilliard, M.R.

    1991-01-01

    This paper discusses the feasibility of adapting concepts and tools that were developed for the US military's transportation management systems to the management of the Federal Waste Management System's (FWMS) Transportation System. Many of the lessons in the development of the planning and scheduling software for the US military are applicable to the development of similar software for the FWMS Transportation System. The resulting system would be invaluable to the US Department of Energy's (DOE) Office of Civilian Radioactive Waste Management (OCRWM), both initially, for long-range planning, and later, in day-to-day scheduling and management activities

  6. 49 CFR 178.348 - Specification DOT 412; cargo tank motor vehicle.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Specification DOT 412; cargo tank motor vehicle... SPECIFICATIONS FOR PACKAGINGS Specifications for Containers for Motor Vehicle Transportation § 178.348 Specification DOT 412; cargo tank motor vehicle. ...

  7. 49 CFR 178.347 - Specification DOT 407; cargo tank motor vehicle.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Specification DOT 407; cargo tank motor vehicle... SPECIFICATIONS FOR PACKAGINGS Specifications for Containers for Motor Vehicle Transportation § 178.347 Specification DOT 407; cargo tank motor vehicle. ...

  8. 49 CFR 178.346 - Specification DOT 406; cargo tank motor vehicle.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Specification DOT 406; cargo tank motor vehicle... SPECIFICATIONS FOR PACKAGINGS Specifications for Containers for Motor Vehicle Transportation § 178.346 Specification DOT 406; cargo tank motor vehicle. ...

  9. 78 FR 75961 - Energy Conservation Program: Test Procedures for Electric Motors

    Science.gov (United States)

    2013-12-13

    ... Conservation Program: Test Procedures for Electric Motors; Final Rule #0;#0;Federal Register / Vol. 78 , No... Procedures for Electric Motors AGENCY: Office of Energy Efficiency and Renewable Energy, Department of Energy... procedures for electric motors to allow currently unregulated motors to be tested by clarifying the test...

  10. Mathematical modeling of molecular motors

    OpenAIRE

    Keller, Peter

    2013-01-01

    Amongst the many complex processes taking place in living cells, transport of cargoes across the cytosceleton is fundamental to cell viability and activity. To move cargoes between the different cell parts, cells employ Molecular Motors. The motors operate by transporting cargoes along the so-called cellular micro-tubules, namely rope-like structures that connect, for instance, the cell-nucleus and outer membrane. We introduce a new Markov Chain, the killed Quasi-Random-Walk, for such transpo...

  11. Motor carrier evaluation program

    International Nuclear Information System (INIS)

    Portsmouth, James

    1992-01-01

    The U.S. Department of Energy-Headquarters (DOE-HQ), Transportation Management Program (TMP) has the overall responsibility to provide a well-managed transportation program for the safe, efficient, and economical transportation of DOE-owned materials. The DOE-TMP has established an excellent safety record in the transportation of hazardous materials including radioactive materials and radioactive wastes. This safety record can be maintained only through continued diligence and sustained effort on the part of the DOE-TMP, its field offices, and the contractors' organizations. Key elements in the DOE'S effective hazardous and radioactive materials shipping program are (1) integrity of packages, (2) strict adherence to regulations and procedures, (3) trained personnel, (4) complete management support, and (5) use of the best commercial carriers. The DOE Motor Carrier Evaluation Program was developed to better define the criteria and methodology needed to identify motor carriers for use in the transportation of Highway Route Controlled Quantities (HRCQ), Truck Load (TL) quantities of radioactive materials, hazardous materials and waste. (author)

  12. 78 FR 68748 - Federal Motor Vehicle Safety Standards; Designated Seating Positions

    Science.gov (United States)

    2013-11-15

    ... Justice (AAJ), Safety Research and Strategies (SRS), Toyota Motor North America (Toyota), Mitsubishi Motors R&D of America (Mitsubishi), and Public Citizen.\\2\\ Toyota also expressed its support for the Alliance's petition. The petitions filed by SAE International and Toyota were styled both as requests for...

  13. 76 FR 52880 - Federal Motor Vehicle Safety Standards; Side Impact Protection

    Science.gov (United States)

    2011-08-24

    ..., Mercedes-Benz USA, Mitsubishi Motors, Porsche, Toyota, and Volkswagen. III. Response to Petition a... various levels of government.'' NHTSA rules can preempt in two ways. First, the National Traffic and Motor... way that NHTSA rules can preempt is dependent upon there being an actual conflict between an FMVSS and...

  14. A Lifecycle Emissions Model (LEM): Lifecycle Emissions from Transportation Fuels, Motor Vehicles, Transportation Modes, Electricity Use, Heating and Cooking Fuels, and Materials, APPENDIX A: Energy Use and Emissions from the Lifecycle of Diesel-Like Fuels Derived From Biomass

    OpenAIRE

    Delucchi, Mark; Lipman, Timothy

    2003-01-01

    An Appendix to the Report, “A Lifecycle Emissions Model (LEM): Lifecycle Emissions From Transportation Fuels, Motor Vehicles, Transportation Modes, Electricity Use, Heating and Cooking Fuels, and Materialsâ€

  15. Local synaptic signaling enhances the stochastic transport of motor-driven cargo in neurons

    KAUST Repository

    Newby, Jay

    2010-08-23

    The tug-of-war model of motor-driven cargo transport is formulated as an intermittent trapping process. An immobile trap, representing the cellular machinery that sequesters a motor-driven cargo for eventual use, is located somewhere within a microtubule track. A particle representing a motor-driven cargo that moves randomly with a forward bias is introduced at the beginning of the track. The particle switches randomly between a fast moving phase and a slow moving phase. When in the slow moving phase, the particle can be captured by the trap. To account for the possibility that the particle avoids the trap, an absorbing boundary is placed at the end of the track. Two local signaling mechanisms-intended to improve the chances of capturing the target-are considered by allowing the trap to affect the tug-of-war parameters within a small region around itself. The first is based on a localized adenosine triphosphate (ATP) concentration gradient surrounding a synapse, and the second is based on a concentration of tau-a microtubule-associated protein involved in Alzheimer\\'s disease-coating the microtubule near the synapse. It is shown that both mechanisms can lead to dramatic improvements in the capture probability, with a minimal increase in the mean capture time. The analysis also shows that tau can cause a cargo to undergo random oscillations, which could explain some experimental observations. © 2010 IOP Publishing Ltd.

  16. 41 CFR 109-38.5103 - Motor vehicle utilization standards.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Motor vehicle... AVIATION, TRANSPORTATION, AND MOTOR VEHICLES 38-MOTOR EQUIPMENT MANAGEMENT 38.51-Utilization of Motor Equipment § 109-38.5103 Motor vehicle utilization standards. (a) The following average utilization standards...

  17. Transport and Sustainability

    DEFF Research Database (Denmark)

    Jørgensen, Kaj

    1997-01-01

    Ph.D. study of the scope for sustainable transport in Denmark, and particularly of the role of the motor vehicle in this context. The distribution of groceries is used as case study of the introduction of the motor vehicle in Denmark, concluding that this has resulted in increases of the transport...

  18. 76 FR 77302 - Federal Transit Administration

    Science.gov (United States)

    2011-12-12

    ... DEPARTMENT OF TRANSPORTATION Federal Transit Administration FY 2011 Discretionary Sustainability... Administration (FTA), DOT. ACTION: FTA Sustainability Program Funds: Announcement of Project Selections. SUMMARY: The U.S. Department of Transportation's (DOT) Federal Transit Administration (FTA) announces the...

  19. 49 CFR 389.19 - Petitions for extension of time to comment.

    Science.gov (United States)

    2010-10-01

    ... CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS RULEMAKING PROCEDURES-FEDERAL MOTOR CARRIER SAFETY REGULATIONS Procedures for Adoption of Rules § 389.19... published in the Federal Register. ...

  20. El rol del transporte público alternativo motorizado en la ciudad / The role of motorized paratransit in the city

    Directory of Open Access Journals (Sweden)

    Rosa Isabel Amorós Zurita

    2013-01-01

    Full Text Available ResumenEl trabajo de investigación presenta una aproximación global sobre las diversas pautas de comportamiento del transporte público alternativo. Es decir, se pretende, a través de la realización de una investigación meramente descriptiva, identificar las diferentes características físicas y de operación de este tipo de transporte en la ciudad. Su estructura incluye el análisis de conceptos y clasificaciones relacionados al transporte público alternativo, la presentación de dos experiencias distintas sobre la utilización de la motocicleta a tres ruedas, uno de los principales tipos de transporte público alternativo motorizado, y finalmente los principales efectos positivos y negativos que causa su circulación a nivel urbano, ambiental, social y económico. Los resultados obtenidos permiten a las instituciones relacionadas con el transporte reflexionar sobre la posibilidad fortalecer esta propuesta de movilidad, necesaria especialmente en países en vías de desarrollo.Palabras claveTransporte público alternativo, ciudad, movilidad.AbstractThis research work presents a new global approach on various paratransit’s behavior patterns in the city. That is to say, through a descriptive research, to allow identifying the physical and operational characteristics of motorized paratransit in the city. The research structure includes the analysis of paratransit’s concepts and classifications, the exposure of two different experiences based on the three-wheeled motorcycle use, one of the main motorized paratransit’s types, and finally its main positive and negative effects in an urban, environmental, social and economic level. The results that were obtained allow transport institutions to reflect on the possibility of strengthen this mobility proposal, required especially in developing countries.KeywordsParatransit, city, mobility.

  1. Double-temperature ratchet model and current reversal of coupled Brownian motors

    Science.gov (United States)

    Li, Chen-Pu; Chen, Hong-Bin; Zheng, Zhi-Gang

    2017-12-01

    On the basis of the transport features and experimental phenomena observed in studies of molecular motors, we propose a double-temperature ratchet model of coupled motors to reveal the dynamical mechanism of cooperative transport of motors with two heads, where the interactions and asynchrony between two motor heads are taken into account. We investigate the collective unidirectional transport of coupled system and find that the direction of motion can be reversed under certain conditions. Reverse motion can be achieved by modulating the coupling strength, coupling free length, and asymmetric coefficient of the periodic potential, which is understood in terms of the effective potential theory. The dependence of the directed current on various parameters is studied systematically. Directed transport of coupled Brownian motors can be manipulated and optimized by adjusting the pulsation period or the phase shift of the pulsation temperature.

  2. Cargo distributions differentiate pathological axonal transport impairments.

    Science.gov (United States)

    Mitchell, Cassie S; Lee, Robert H

    2012-05-07

    Axonal transport is an essential process in neurons, analogous to shipping goods, by which energetic and cellular building supplies are carried downstream (anterogradely) and wastes are carried upstream (retrogradely) by molecular motors, which act as cargo porters. Impairments in axonal transport have been linked to devastating and often lethal neurodegenerative diseases, such as Amyotrophic Lateral Sclerosis, Huntington's, and Alzheimer's. Axonal transport impairment types include a decrease in available motors for cargo transport (motor depletion), the presence of defective or non-functional motors (motor dilution), and the presence of increased or larger cargos (protein aggregation). An impediment to potential treatment identification has been the inability to determine what type(s) of axonal transport impairment candidates that could be present in a given disease. In this study, we utilize a computational model and common axonal transport experimental metrics to reveal the axonal transport impairment general characteristics or "signatures" that result from three general defect types of motor depletion, motor dilution, and protein aggregation. Our results not only provide a means to discern these general impairments types, they also reveal key dynamic and emergent features of axonal transport, which potentially underlie multiple impairment types. The identified characteristics, as well as the analytical method, can be used to help elucidate the axonal transport impairments observed in experimental and clinical data. For example, using the model-predicted defect signatures, we identify the defect candidates, which are most likely to be responsible for the axonal transport impairments in the G93A SOD1 mouse model of ALS. Copyright © 2012 Elsevier Ltd. All rights reserved.

  3. 49 CFR 384.221 - Out-of-service regulations (intoxicating beverage).

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Out-of-service regulations (intoxicating beverage...) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY... Compliance by States § 384.221 Out-of-service regulations (intoxicating beverage). The State shall adopt, and...

  4. The contribution of transport to the overall risk of nuclear energy

    International Nuclear Information System (INIS)

    Huebenthal, K.

    1985-01-01

    The overall risk of nuclear energy is minute as compared with other natural and civilization-effected risks. The contribution of the transport of radioactive materials to this overall risk is not significant. The paper touches the following subjects: Project Safety Studies of Waste Management (PSE), System Studies Alternative Waste Disposal Technologies (PAE), Motor Columbus and the Federal Gazette 10/2160 of October 1984. Collective doses of the population are given for the fuel cycle with various waste management technologies. (DG) [de

  5. 49 CFR 268.7 - Federal/State share and restrictions on the uses of Federal Maglev Funds.

    Science.gov (United States)

    2010-10-01

    ... of Federal Maglev Funds. 268.7 Section 268.7 Transportation Other Regulations Relating to... Federal Maglev Funds. (a) Federal share. The Federal share of Full Projects Costs shall be not more than 2...) Restrictions on the uses of Federal Maglev Funds. (1) Federal Maglev Funds may be applied only to Eligible...

  6. Superresolution imaging of dynamic MreB filaments in B. subtilis--a multiple-motor-driven transport?

    Science.gov (United States)

    Olshausen, Philipp V; Defeu Soufo, Hervé Joël; Wicker, Kai; Heintzmann, Rainer; Graumann, Peter L; Rohrbach, Alexander

    2013-09-03

    The cytoskeletal protein MreB is an essential component of the bacterial cell-shape generation system. Using a superresolution variant of total internal reflection microscopy with structured illumination, as well as three-dimensional stacks of deconvolved epifluorescence microscopy, we found that inside living Bacillus subtilis cells, MreB forms filamentous structures of variable lengths, typically not longer than 1 μm. These filaments move along their orientation and mainly perpendicular to the long bacterial axis, revealing a maximal velocity at an intermediate length and a decreasing velocity with increasing filament length. Filaments move along straight trajectories but can reverse or alter their direction of propagation. Based on our measurements, we provide a mechanistic model that is consistent with all observations. In this model, MreB filaments mechanically couple several motors that putatively synthesize the cell wall, whereas the filaments' traces mirror the trajectories of the motors. On the basis of our mechanistic model, we developed a mathematical model that can explain the nonlinear velocity length dependence. We deduce that the coupling of cell wall synthesis motors determines the MreB filament transport velocity, and the filament mechanically controls a concerted synthesis of parallel peptidoglycan strands to improve cell wall stability. Copyright © 2013 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  7. Driving forces: Motor vehicle trends and their implications for global warming, energy strategies, and transportation planning

    International Nuclear Information System (INIS)

    MacKenzie, J.J.; Walsh, M.P.

    1990-01-01

    Cars, trucks, and other vehicles have long been linked to smog and other urban pollution, but the part they play in the larger complex of atmospheric and energy ills that we now face is often overlooked. In Driving Forces: Motor Vehicle Trends and Their Implications for Global Warming, Energy Strategies, and Transportation Planning, James J. MacKenzie, senior associate in World Resources Institute's Program in Climate, Energy, and Pollution, and Michael P. Walsh, an international consultant on transportation and environmental issues, fill in this knowledge gap with new data and analyses. They spell out four policy shifts that can help hold the line on global warming: improve new-vehicle efficiency; make transportation more efficient; cut other greenhouse gas emissions; create the green car of the future. The report focuses especially on the US, which pioneered the automotive revolution and leads the world in oil imports and emissions

  8. Federal Motor Vehicle Safety Standards Interpretations

    Data.gov (United States)

    Department of Transportation — NHTSA's Chief Counsel interprets the statutes that the agency administers and the regulations that it promulgates. The Chief Counsel's interpretations, issued in the...

  9. 41 CFR 109-38.5105 - Motor vehicle local use objectives.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Motor vehicle local use..., TRANSPORTATION, AND MOTOR VEHICLES 38-MOTOR EQUIPMENT MANAGEMENT 38.51-Utilization of Motor Equipment § 109-38.5105 Motor vehicle local use objectives. (a) Individual motor vehicle utilization cannot always be...

  10. Transport of radioactive materials in the Federal Republic of Germany (FRG) since 3. October 1990

    International Nuclear Information System (INIS)

    Alter, U.; Collin, F.W.; Fasten, C.

    1993-01-01

    The paper presents a survey on the transport of radioactive materials in the FRG. For shipments of nuclear material and large sources in the FRG - and also in the former German Democratic Republic - a license from the Federal Office for Radiation Protection (the competent authority in the FRG) due to the Atomic law and Radiological Protection Requirements are necessary. (J.P.N.)

  11. 41 CFR 109-38.5104 - Other motor equipment utilization standards.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Other motor equipment... AVIATION, TRANSPORTATION, AND MOTOR VEHICLES 38-MOTOR EQUIPMENT MANAGEMENT 38.51-Utilization of Motor Equipment § 109-38.5104 Other motor equipment utilization standards. No utilization standards are...

  12. 48 CFR 970.5223-5 - DOE motor vehicle fleet fuel efficiency.

    Science.gov (United States)

    2010-10-01

    ... and Contract Clauses for Management and Operating Contracts 970.5223-5 DOE motor vehicle fleet fuel..., insert the following clause in contracts providing for Contractor management of the motor vehicle fleet... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false DOE motor vehicle fleet...

  13. Educational and technical assistance to CMV drivers and motor carriers

    Science.gov (United States)

    1999-07-01

    The Peer Exchange is a process adopted by the Office of Motor Carrier and Highway Safety in which teams of professionals, representing state and federal government and private industry, identify effective commercial motor vehicle safety findings for ...

  14. 49 CFR 574.9 - Requirements for motor vehicle dealers.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Requirements for motor vehicle dealers. 574.9... RECORDKEEPING § 574.9 Requirements for motor vehicle dealers. (a) Each motor vehicle dealer who sells a used motor vehicle for purposes other than resale, who leases a motor vehicle for more than 60 days, that is...

  15. 14 CFR 25.1365 - Electrical appliances, motors, and transformers.

    Science.gov (United States)

    2010-01-01

    ... Equipment § 25.1365 Electrical appliances, motors, and transformers. (a) Domestic appliances must be... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Electrical appliances, motors, and transformers. 25.1365 Section 25.1365 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF...

  16. Transportation safety training

    International Nuclear Information System (INIS)

    Jones, E.

    1990-01-01

    Over the past 25 years extensive federal legislation involving the handling and transport of hazardous materials/waste has been passed that has resulted in numerous overlapping regulations administered and enforced by different federal agencies. The handling and transport of hazardous materials/waste involves a significant number of workers who are subject to a varying degree of risk should an accident occur during handling or transport. Effective transportation training can help workers address these risks and mitigate them, and at the same time enable ORNL to comply with the federal regulations concerning the transport of hazardous materials/waste. This presentation will outline how the Environmental and Health Protection Division's Technical Resources and Training Section at the Oak Ridge National Laboratory, working with transportation and waste disposal personnel, have developed and implemented a comprehensive transportation safety training program to meet the needs of our workers while satisfying appropriate federal regulations. 8 refs., 3 tabs

  17. 75 FR 31815 - Meeting of the Department of Justice's (DOJ's) National Motor Vehicle Title Information System...

    Science.gov (United States)

    2010-06-04

    ... Department of Justice's (DOJ's) National Motor Vehicle Title Information System (NMVTIS) Federal Advisory... announcement of a meeting of DOJ's National Motor Vehicle Title Information System (NMVTIS) Federal Advisory... 7th Street, NW., Washington, DC 20531; Phone: (202) 305-1661. FOR FURTHER INFORMATION CONTACT: Alissa...

  18. 76 FR 8778 - Meeting of the Department of Justice's (DOJ's) National Motor Vehicle Title Information System...

    Science.gov (United States)

    2011-02-15

    ... Department of Justice's (DOJ's) National Motor Vehicle Title Information System (NMVTIS) Federal Advisory... announcement of a meeting of DOJ's National Motor Vehicle Title Information System (NMVTIS) Federal Advisory... 7th Street, NW., Washington, DC 20531; Phone: (202) 305-1661. FOR FURTHER INFORMATION CONTACT: Alissa...

  19. The Molecular Motor KIF1A Transports the TrkA Neurotrophin Receptor and Is Essential for Sensory Neuron Survival and Function.

    Science.gov (United States)

    Tanaka, Yosuke; Niwa, Shinsuke; Dong, Ming; Farkhondeh, Atena; Wang, Li; Zhou, Ruyun; Hirokawa, Nobutaka

    2016-06-15

    KIF1A is a major axonal transport motor protein, but its functional significance remains elusive. Here we show that KIF1A-haploinsufficient mice developed sensory neuropathy. We found progressive loss of TrkA(+) sensory neurons in Kif1a(+/-) dorsal root ganglia (DRGs). Moreover, axonal transport of TrkA was significantly disrupted in Kif1a(+/-) neurons. Live imaging and immunoprecipitation assays revealed that KIF1A bound to TrkA-containing vesicles through the adaptor GTP-Rab3, suggesting that TrkA is a cargo of the KIF1A motor. Physiological measurements revealed a weaker capsaicin response in Kif1a(+/-) DRG neurons. Moreover, these neurons were hyposensitive to nerve growth factor, which could explain the reduced neuronal survival and the functional deficiency of the pain receptor TRPV1. Because phosphatidylinositol 3-kinase (PI3K) signaling significantly rescued these phenotypes and also increased Kif1a mRNA, we propose that KIF1A is essential for the survival and function of sensory neurons because of the TrkA transport and its synergistic support of the NGF/TrkA/PI3K signaling pathway. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Correlations and symmetry of interactions influence collective dynamics of molecular motors

    International Nuclear Information System (INIS)

    Celis-Garza, Daniel; Teimouri, Hamid; Kolomeisky, Anatoly B

    2015-01-01

    Enzymatic molecules that actively support many cellular processes, including transport, cell division and cell motility, are known as motor proteins or molecular motors. Experimental studies indicate that they interact with each other and they frequently work together in large groups. To understand the mechanisms of collective behavior of motor proteins we study the effect of interactions in the transport of molecular motors along linear filaments. It is done by analyzing a recently introduced class of totally asymmetric exclusion processes that takes into account the intermolecular interactions via thermodynamically consistent approach. We develop a new theoretical method that allows us to compute analytically all dynamic properties of the system. Our analysis shows that correlations play important role in dynamics of interacting molecular motors. Surprisingly, we find that the correlations for repulsive interactions are weaker and more short-range than the correlations for the attractive interactions. In addition, it is shown that symmetry of interactions affect dynamic properties of molecular motors. The implications of these findings for motor proteins transport are discussed. Our theoretical predictions are tested by extensive Monte Carlo computer simulations. (paper)

  1. 78 FR 26106 - Pilot Program on NAFTA Trucking Provisions

    Science.gov (United States)

    2013-05-03

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No FMCSA-2011-0097] Pilot Program on NAFTA Trucking Provisions AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice; correction. SUMMARY: The FMCSA published a document in the Federal Register of...

  2. Superresolution Imaging of Dynamic MreB Filaments in B. subtilis—A Multiple-Motor-Driven Transport?

    Science.gov (United States)

    Olshausen, Philipp v.; Defeu Soufo, Hervé Joël; Wicker, Kai; Heintzmann, Rainer; Graumann, Peter L.; Rohrbach, Alexander

    2013-01-01

    The cytoskeletal protein MreB is an essential component of the bacterial cell-shape generation system. Using a superresolution variant of total internal reflection microscopy with structured illumination, as well as three-dimensional stacks of deconvolved epifluorescence microscopy, we found that inside living Bacillus subtilis cells, MreB forms filamentous structures of variable lengths, typically not longer than 1 μm. These filaments move along their orientation and mainly perpendicular to the long bacterial axis, revealing a maximal velocity at an intermediate length and a decreasing velocity with increasing filament length. Filaments move along straight trajectories but can reverse or alter their direction of propagation. Based on our measurements, we provide a mechanistic model that is consistent with all observations. In this model, MreB filaments mechanically couple several motors that putatively synthesize the cell wall, whereas the filaments’ traces mirror the trajectories of the motors. On the basis of our mechanistic model, we developed a mathematical model that can explain the nonlinear velocity length dependence. We deduce that the coupling of cell wall synthesis motors determines the MreB filament transport velocity, and the filament mechanically controls a concerted synthesis of parallel peptidoglycan strands to improve cell wall stability. PMID:24010660

  3. 49 CFR 393.17 - Lamps and reflectors-combinations in driveaway-towaway operation.

    Science.gov (United States)

    2010-10-01

    ... motor vehicles engaged in driveaway-towaway operation must be equipped with operative lamps and... used off road for dwelling or commercial purposes. (1) When the vehicle is operated in accordance with... (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER...

  4. 49 CFR 591.1 - Scope.

    Science.gov (United States)

    2010-10-01

    ... OF TRANSPORTATION (CONTINUED) IMPORTATION OF VEHICLES AND EQUIPMENT SUBJECT TO FEDERAL SAFETY, BUMPER AND THEFT PREVENTION STANDARDS § 591.1 Scope. This part establishes procedures governing the importation of motor vehicles and motor vehicle equipment subject to the Federal motor vehicle safety, bumper...

  5. All Internal Segmental Bone Transport and Optional Lengthening With a Newly Developed Universal Cylinder-Kombi-Tube Module for Motorized Nails-Description of a Surgical Technique.

    Science.gov (United States)

    Krettek, Christian; El Naga, Ashraf

    2017-10-01

    Segmental transport is an effective method of treatment for segmental defects, but the need for external fixation during the transport phase is a disadvantage. To avoid external fixation, we have developed a Cylinder-Kombi-Tube Segmental Transport (CKTST) module for combination with a commercially available motorized lengthening nail. This CKTST module allows for an all-internal segmental bone transport and also allows for optional lengthening if needed. The concept and surgical technique of CKTST are described and illustrated with a clinical case.

  6. Controllable molecular motors engineered from myosin and RNA

    Science.gov (United States)

    Omabegho, Tosan; Gurel, Pinar S.; Cheng, Clarence Y.; Kim, Laura Y.; Ruijgrok, Paul V.; Das, Rhiju; Alushin, Gregory M.; Bryant, Zev

    2018-01-01

    Engineering biomolecular motors can provide direct tests of structure-function relationships and customized components for controlling molecular transport in artificial systems1 or in living cells2. Previously, synthetic nucleic acid motors3-5 and modified natural protein motors6-10 have been developed in separate complementary strategies to achieve tunable and controllable motor function. Integrating protein and nucleic-acid components to form engineered nucleoprotein motors may enable additional sophisticated functionalities. However, this potential has only begun to be explored in pioneering work harnessing DNA scaffolds to dictate the spacing, number and composition of tethered protein motors11-15. Here, we describe myosin motors that incorporate RNA lever arms, forming hybrid assemblies in which conformational changes in the protein motor domain are amplified and redirected by nucleic acid structures. The RNA lever arm geometry determines the speed and direction of motor transport and can be dynamically controlled using programmed transitions in the lever arm structure7,9. We have characterized the hybrid motors using in vitro motility assays, single-molecule tracking, cryo-electron microscopy and structural probing16. Our designs include nucleoprotein motors that reversibly change direction in response to oligonucleotides that drive strand-displacement17 reactions. In multimeric assemblies, the controllable motors walk processively along actin filaments at speeds of 10-20 nm s-1. Finally, to illustrate the potential for multiplexed addressable control, we demonstrate sequence-specific responses of RNA variants to oligonucleotide signals.

  7. Vision and commercial motor vehicle driver safety : vol. 1 : evidence report

    Science.gov (United States)

    2008-06-06

    The purpose of this evidence report is to address several key questions posed by the Federal Motor Carrier Safety Administration (FMCSA) that pertain to vision and commercial motor vehicle (CMV) driver safety. Each of these key questions was develope...

  8. 78 FR 39057 - Hours of Service of Drivers; Renewal and Expansion of American Pyrotechnics Association Exemption...

    Science.gov (United States)

    2013-06-28

    ... any traffic laws, or motor carrier safety regulations, and i. The total driving time and the total on... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2007... From the 14-Hour Rule During Independence Day Celebrations AGENCY: Federal Motor Carrier Safety...

  9. 49 CFR 374.503 - Authority.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Authority. 374.503 Section 374.503 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION... Incidental Charter Rights § 374.503 Authority. Motor carriers transporting passengers, in interstate or...

  10. 75 FR 38423 - Minimum Levels of Financial Responsibility for Motor Carriers

    Science.gov (United States)

    2010-07-02

    ... Canada-domiciled motor carriers and freight forwarders to maintain, as acceptable evidence of financial... Superintendent of Financial Institutions PAU--Power of Attorney and Undertaking PACICC--Property and Casualty... subject to FMCSA's current Federal motor carrier financial responsibility rules. Canada requested that...

  11. 40 CFR 93.118 - Criteria and procedures: Motor vehicle emissions budget.

    Science.gov (United States)

    2010-07-01

    ... emissions budget. 93.118 Section 93.118 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... and procedures: Motor vehicle emissions budget. (a) The transportation plan, TIP, and project not from a conforming transportation plan and TIP must be consistent with the motor vehicle emissions budget...

  12. 76 FR 78966 - Federal Aviation Administration

    Science.gov (United States)

    2011-12-20

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Approval of Noise Compatibility Program for Kona International Airport at Keahole, Keahole, North Kona, HI AGENCY: Federal Aviation Administration, DOT. ACTION: Notice. SUMMARY: The Federal Aviation Administration (FAA) announces its findings on...

  13. 75 FR 6433 - Federal Aviation Administration

    Science.gov (United States)

    2010-02-09

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of Availability of a Draft... 9, West Chicago, IL AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of... Surveillance Radar, Model 9, West Chicago, Illinois. SUMMARY: The Federal Aviation Administration (FAA...

  14. 75 FR 12809 - Federal Aviation Administration

    Science.gov (United States)

    2010-03-17

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of Intent To Rule on Request...: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Request to Release Airport Property. SUMMARY... Nicely, Manager, Federal Aviation Administration, Southwest Region, Airports Division, Texas Airports...

  15. 75 FR 18014 - Federal Highway Administration

    Science.gov (United States)

    2010-04-08

    ... DEPARTMENT OF TRANSPORTATION Federal Highway Administration AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice of Availability regarding a Finding of No Significant Impact (FONSI): U.S.... FOR FURTHER INFORMATION CONTACT: Federal Highway Administration, Kentucky Division: Mr. Greg Rawlings...

  16. Cryogenic Electric Motor Tested

    Science.gov (United States)

    Brown, Gerald V.

    2004-01-01

    Technology for pollution-free "electric flight" is being evaluated in a number of NASA Glenn Research Center programs. One approach is to drive propulsive fans or propellers with electric motors powered by fuel cells running on hydrogen. For large transport aircraft, conventional electric motors are far too heavy to be feasible. However, since hydrogen fuel would almost surely be carried as liquid, a propulsive electric motor could be cooled to near liquid hydrogen temperature (-423 F) by using the fuel for cooling before it goes to the fuel cells. Motor windings could be either superconducting or high purity normal copper or aluminum. The electrical resistance of pure metals can drop to 1/100th or less of their room-temperature resistance at liquid hydrogen temperature. In either case, super or normal, much higher current density is possible in motor windings. This leads to more compact motors that are projected to produce 20 hp/lb or more in large sizes, in comparison to on the order of 2 hp/lb for large conventional motors. High power density is the major goal. To support cryogenic motor development, we have designed and built in-house a small motor (7-in. outside diameter) for operation in liquid nitrogen.

  17. Electric motor-transformer aggregate in hermetic objects of transport vehicles

    Science.gov (United States)

    Zabora, Igor

    2017-10-01

    The construction and features of operation for new electrical unit - electric motor-transformer aggregate (DTA) are considered. Induction motors are intended for operation in hermetic plants with extreme conditions surrounding gas, steam-to-gas and liquid environment at a high temperature (to several hundred of degrees). Main objective of spent researches is the substantiation of possibility reliable and effective electric power transform with electric machine means directly in hermetic objects with extreme conditions environment by means of new DTA. The principle and job analysis of new disk induction motors of block-module type are observed.

  18. 46 CFR 151.50-6 - Motor fuel antiknock compounds.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Motor fuel antiknock compounds. 151.50-6 Section 151.50... BARGES CARRYING BULK LIQUID HAZARDOUS MATERIAL CARGOES Special Requirements § 151.50-6 Motor fuel antiknock compounds. When transporting motor fuel antiknock compounds containing tetraethyl lead and...

  19. 49 CFR 1325.3 - Federal office.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Federal office. 1325.3 Section 1325.3... FEDERAL OFFICE OR THEIR REPRESENTATIVES § 1325.3 Federal office. For the purposes of this section, Federal office means the office of President or Vice President of the United States; or of Senator or...

  20. 78 FR 25524 - Federal Aviation Administration

    Science.gov (United States)

    2013-05-01

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of Request To Release Airport Property AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Intent to Rule on Request to... address: Lynn D. Martin, Airports Compliance Specialist, Federal Aviation Administration, Airports...

  1. 77 FR 64837 - Federal Aviation Administration

    Science.gov (United States)

    2012-10-23

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Fourth Meeting: RTCA Special Committee 227, Standards of Navigation Performance AGENCY: Federal Aviation Administration (FAA), U.S... Operations Group, Federal Aviation Administration. [FR Doc. 2012-26034 Filed 10-22-12; 8:45 am] BILLING CODE...

  2. 78 FR 13395 - Federal Aviation Administration

    Science.gov (United States)

    2013-02-27

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of Availability of Draft...: Federal Aviation Administration (FAA), DOT. ACTION: Notice of availability and request for comments... 4. U.S. Mail: Leslie Grey--AAL-614, Federal Aviation Administration, Airports Division, 222 West 7th...

  3. 49 CFR 41.117 - Buildings built with Federal assistance.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Buildings built with Federal assistance. 41.117 Section 41.117 Transportation Office of the Secretary of Transportation SEISMIC SAFETY § 41.117 Buildings built with Federal assistance. (a) Each DOT Operating Administration assisting in the financing, through...

  4. 41 CFR 101-26.501 - Purchase of new motor vehicles.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Purchase of new motor vehicles. 101-26.501 Section 101-26.501 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 26-PROCUREMENT...

  5. Transportation and air quality

    International Nuclear Information System (INIS)

    Roseland, M.

    1992-01-01

    In the greater Vancouver regional district (GVRD), some 80% of the annual production of 600,000 tonnes of air pollutants come from motor vehicles. Three critical air quality issues in the GVRD are discussed: local air pollution, ozone layer depletion, and greenhouse gas emissions, all of which are fundamentally linked to transportation. Overall air quality in the GVRD has been judged acceptable by current federal standards, but ground-level ozone has exceeded maximum tolerable levels at some locations and concentrations of suspended particulates are above maximum acceptable levels. Serious deterioration in air quality has been predicted unless a concerted effort is made to manage air quality on an airshed-wide basis. The GVRD is developing Canada's first Air Management Plan with the goal of halving atmospheric emissions by 2000. GVRD transportation priorities stress public transit, walking, cycling, car pooling, and reducing of travel demand; however, the viability of such strategies depends on decisions made outside the transportation sector. Restricted authority and jurisdiction also hinder GVRD goals; the regional level of government has no authority over highways or transit and only has authority for pollution control in some parts of the Fraser Valley. Airshed quality management, using the Los Angeles example, is seen as a possible direction for future GVRD policymaking in the transportation sector. A single regional planning agency with responsibility for transportation, land use, and air quality management appears as the best option for an integrated approach to solve multiple problems. 19 refs

  6. Safety And Promotion in the Federal Aviation Administration- Enabling Safe and Successful Commercial Space Transportation

    Science.gov (United States)

    Repcheck, Randall J.

    2010-09-01

    The United States Federal Aviation Administration’s Office of Commercial Space Transportation(AST) authorizes the launch and reentry of expendable and reusable launch vehicles and the operation of launch and reentry sites by United States citizens or within the United States. It authorizes these activities consistent with public health and safety, the safety of property, and the national security and foreign policy interests of the United States. In addition to its safety role, AST has the role to encourage, facilitate, and promote commercial space launches and reentries by the private sector. AST’s promotional role includes, among other things, the development of information of interest to industry, the sharing of information of interest through a variety of methods, and serving as an advocate for Commercial Space Transportation within the United States government. This dual safety and promotion role is viewed by some as conflicting. AST views these two roles as complementary, and important for the current state of commercial space transportation. This paper discusses how maintaining a sound safety decision-making process, maintaining a strong safety culture, and taking steps to avoid complacency can together enable safe and successful commercial space transportation.

  7. Louisiana SIP: LAC 33:III Ch. 14 Subchap B, 1431 to 1434--Conformity to State or Federal Implementation Plans of Transportation Plans, Programs, and Projects Developed, Funded, or Approved Under Title 23 U.S.C. or the Federal Transit Laws

    Science.gov (United States)

    Louisiana SIP: LAC 33:III Ch. 14 Subchap B, 1431 to 1434--Conformity to State or Federal Implementation Plans of Transportation Plans, Programs, and Projects Developed, Funded, or Approved Under Title 23 U.S.C. or the Federal Transit Laws

  8. 49 CFR 177.823 - Movement of motor vehicles in emergency situations.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Movement of motor vehicles in emergency situations... CARRIAGE BY PUBLIC HIGHWAY General Information and Regulations § 177.823 Movement of motor vehicles in... government; (2) The carrier has permission from the Department; or (3) Movement of the transport vehicle is...

  9. 76 FR 37682 - Airworthiness Directives; Teledyne Continental Motors (TCM) and Rolls-Royce Motors Ltd. (R-RM...

    Science.gov (United States)

    2011-06-28

    ... holidays. For service information identified in this AD, contact Teledyne Continental Motors, Inc., PO Box... Friday, except Federal holidays. The AD docket contains this proposed AD, the regulatory evaluation, any... applicability listed magneto S/Ns of 99110001 through 9912999 inclusive. This proposed AD supersedure would...

  10. Energy, Pollutant Emissions and Other Negative Externality Savings from Curbing Individual Motorized Transportation (IMT: A Low Cost, Low Technology Scenario Analysis in Brazilian Urban Areas

    Directory of Open Access Journals (Sweden)

    Ursula Maruyama

    2012-03-01

    Full Text Available This article examines the inefficient use of resources in the Brazilian transportation system. The energy use growth and external cost generation in this essential economic sector are considerable, and the trend is towards an increasing problem in the coming years. The continued expansion of Brazilian cities and the increase in demand for mobility is a result of a substantial growth in the number of road transport users, as increased earnings enable lower income groups to acquire and use individual motorized means of transport. The aim of this paper is to estimate the potential gains from reducing individual motorized transport by the year 2020. This investigation concludes that in a conservationist scenario, by prioritizing low cost, low technology public policies—which include operation of Bus Rapid Transit systems, walking and cycling facilities and congestion charges, among others—it should be possible to save over USD 30 billion and USD 26 billion in external transportation and infrastructure costs, respectively, up to 2020. In addition, these public policies can save more than 35 million Tons of Oil Equivalents in energy consumption and avoid almost 4,000 thousand tons of local pollution emissions and 37,500 thousand tons of GHG emissions in the same period.

  11. 41 CFR 109-38.301-1.53 - Responsibilities of motor vehicle operators.

    Science.gov (United States)

    2010-07-01

    ... motor vehicle operators. 109-38.301-1.53 Section 109-38.301-1.53 Public Contracts and Property... MANAGEMENT REGULATIONS AVIATION, TRANSPORTATION, AND MOTOR VEHICLES 38-MOTOR EQUIPMENT MANAGEMENT 38.3-Official Use of Government Motor Vehicles § 109-38.301-1.53 Responsibilities of motor vehicle operators...

  12. 75 FR 61552 - Federal Railroad Administration

    Science.gov (United States)

    2010-10-05

    ... DEPARTMENT OF TRANSPORTATION Federal Railroad Administration Notice of Informational Filing In accordance with Section 236.913 of Title 49 of the Code of Federal Regulations (CFR), notice is hereby given that the Federal Railroad Administration (FRA) has received an informational filing from the Northeast...

  13. 41 CFR 109-38.204-4 - Report of exempted motor vehicles.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Report of exempted motor..., TRANSPORTATION, AND MOTOR VEHICLES 38-MOTOR EQUIPMENT MANAGEMENT 38.2-Registration, Identification, and Exemptions § 109-38.204-4 Report of exempted motor vehicles. DOE offices shall provide upon request the...

  14. Study on occupational and nonoccupational risk factors and health of motor transport workers

    Directory of Open Access Journals (Sweden)

    V. Obelenis

    2003-08-01

    Full Text Available The study on work conditions, lifestyle, psychosocial factors and health was carried out in three different urban motor transport companies. 788 workers of the main occupations were interviewed using a questionnaire. The main occupational hazards are low air temperature, draughts, exposure to diesel fuel, cooling oil, noise, vibration, musculoskeletal exertion. Workers do not lead a healthy lifestyle: 46,0 % - are smokers, 83,0% - use alcohol, 53,0 % are physically inactive, 82,0 % lead a malnutrition regimen, 27,0 % experience stressful situations at work every day. Musculoskeletal disorders make up 46,2 %, respiratory 22,2 %, gastrointestinal 17,3 % and central nervous system dysfunction 32,2 %. Musculoskeletal disorders are related to poor ergonomic and workplace design, long working hours, senior age and long professional work experience (p<0,05-0,002.

  15. Industry agreement on efficient electrical motors

    International Nuclear Information System (INIS)

    Schnyder, G.

    2004-01-01

    This comprehensive final report presents the results of a project carried out on behalf of the Swiss Federal Office of Energy (SFOE) and the Swiss Automation Pool (SAP) concerning the efficiency of electrical drives. The main goal of the project was to conclude a target agreement between the federal government and the Swiss electric motors/drives industry. This involves the promotion of the highest, 'eff1' energy-efficiency category of the three categories defined by the European Committee of Manufacturers of Electrical Machines and Power Electronics (CEMP). The report presents the findings of the project and recommends the banning of the use of motors in the lowest, 'eff3' category. Comparisons are made between the CEMP standards and further standards and promotion programmes in the USA and in Great Britain. Associated measures to be taken to aid the promotion of the drive standard are discussed

  16. 29 CFR 1926.902 - Surface transportation of explosives.

    Science.gov (United States)

    2010-07-01

    ... electric) shall not be transported in the same vehicle with other explosives. (e) Vehicles used for... prevent contact with containers of explosives. (h) Every motor vehicle or conveyance used for transporting... Carriers. (b) Motor vehicles or conveyances transporting explosives shall only be driven by, and be in the...

  17. 49 CFR 325.73 - Microphone distance correction factors. 1

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Microphone distance correction factors. 1 325.73 Section 325.73 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR... MOTOR CARRIER NOISE EMISSION STANDARDS Correction Factors § 325.73 Microphone distance correction...

  18. In vivo control mechanisms of motor-cargo movement on microtubules

    Science.gov (United States)

    Gunawardena, Shermali

    2014-03-01

    Within axons, molecular motors transport essential components required for neuronal growth and viability. Although many levels of regulation must exist for proper anterograde and retrograde transport of vital proteins, little is known about these mechanisms. Previous work suggested that the amyloid precursor protein (APP) functions as a kinesin-1 receptor during transport. However, how APP vesicle motility is regulated is unclear. Using genetics and in vivo imaging in Drosophila we showed that reduction of presenilin (PS) substantially increased anterograde and retrograde APP vesicle velocities. Strikingly, PS deficiency had no effect on an unrelated cargo vesicle containing synaptotagmin, which is powered by a different kinesin motor. Increased PS-mediated velocities required functional kinesin-1 and dynein motors. We also found that these PS-mediated effects on motor protein function were mediated via a pathway that involves glycogen synthase kinase-3 β (GSK-3 β) . PS genetically interacted with GSK-3 β in an activity dependent manner. Excess of active GSK-3 β perturbed transport by causing axonal blockages, which were enhanced by reduction of kinesin-1 or dynein, while excess of non-functional GSK-3 β had no effect. Strikingly, GSK-3 β-activity dependent transport defects were enhanced by reduction of PS. Collectively, our findings suggest that PS and GSK-3 β are required for normal motor protein function, and we propose a model in which PS likely regulates GSK-3 β activity during transport. These findings have important implications for our understanding of the complex regulatory machinery that must exist in vivo and how this system is coordinated during vesicle motility on microtubules.

  19. 78 FR 20881 - Control of Air Pollution From Motor Vehicles: Tier 3 Motor Vehicle Emission and Fuel Standards...

    Science.gov (United States)

    2013-04-08

    ...The EPA is announcing two public hearings to be held for the proposed rule ``Control of Air Pollution from Motor Vehicles: Tier 3 Motor Vehicle Emission and Fuel Standards'' (the proposed rule is hereinafter referred to as ``Tier 3''), which will be published separately in the Federal Register. The hearings will be held in Philadelphia, PA on April 24, 2013 and in Chicago, IL on April 29, 2013. The comment period for the proposed rulemaking will end on June 13, 2013.

  20. Electrodynamic ratchet motor.

    Science.gov (United States)

    Lim, Jiufu; Sader, John E; Mulvaney, Paul

    2009-03-01

    Brownian ratchets produce directed motion through rectification of thermal fluctuations and have been used for separation processes and colloidal transport. We propose a flashing ratchet motor that enables the transduction of electrical energy into rotary micromechanical work. This is achieved through torque generation provided by boundary shaping of equipotential surfaces. The present device contrasts to previous implementations that focus on translational motion. Stochastic simulations elucidate the performance characteristics of this device as a function of its geometry. Miniaturization to nanoscale dimensions yields rotational speeds in excess of 1 kHz, which is comparable to biomolecular motors of similar size.

  1. Air pollution from motor vehicle emissions

    International Nuclear Information System (INIS)

    Petrushevska, Ljubica

    1996-01-01

    This paper presents some aspects of air pollution from motor vehicle emissions as: characteristic primary and secondary pollutants, dependence of the motor vehicle emission from the engine type; the relationship of typical engine emission and performance to air-fuel ratio, transport of pollutants from mobile sources of emissions, as well as some world experiences in the control approaches for exhaust emissions. (author)

  2. Analysis of FMCSA civil penalty enforcement cases, 2010–14 : analysis brief.

    Science.gov (United States)

    2016-01-01

    The Federal Motor Carrier Safety Administration (FMCSA) is responsible for ensuring that all truck and bus companies, drivers and other entities regulated by the U.S. Department of Transportation (USDOT) comply with all Federal Motor Carrier Safety R...

  3. Stochastic models of intracellular transport

    KAUST Repository

    Bressloff, Paul C.; Newby, Jay M.

    2013-01-01

    mechanisms for intracellular transport: passive diffusion and motor-driven active transport. Diffusive transport can be formulated in terms of the motion of an overdamped Brownian particle. On the other hand, active transport requires chemical energy, usually

  4. 49 CFR 231.22 - Operation of track motor cars.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Operation of track motor cars. 231.22 Section 231... motor cars. On and after August 1, 1963, it shall be unlawful for any railroad subject to the requirements of the Safety Appliance Acts to operate or permit to be operated on its line track motor cars to...

  5. 76 FR 39240 - Federal Acquisition Regulation; Encouraging Contractor Policies To Ban Text Messaging While Driving

    Science.gov (United States)

    2011-07-05

    ... Executive Order (E.O.) 13513, dated October 1, 2009, entitled ``Federal Leadership on Reducing Text..., entitled ``Federal Leadership on Reducing Text Messaging while Driving.'' The rule requires Government... modified to include the Federal Motor Carrier Safety Administration (FMCSA) definitions of electronic...

  6. 49 CFR 381.330 - What am I required to do if the FMCSA grants my application for an exemption?

    Science.gov (United States)

    2010-10-01

    ... Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL... (3) Continuation of the exemption is determined by the FMCSA to be inconsistent with the goals and objectives of the FMCSRs. ...

  7. 75 FR 36779 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-06-28

    ... deficiency for 3 years. Recent driving performance is especially important in evaluating future safety... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-1999... AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of final disposition...

  8. Striatal Dopamine Depletion Patterns and Early Non-Motor Burden in Parkinsons Disease.

    Directory of Open Access Journals (Sweden)

    Su Jin Chung

    Full Text Available The mechanism underlying non-motor symptoms in Parkinson's disease has not yet been elucidated. In this study, we hypothesized that Parkinson patients with more non-motor symptoms have a different pattern of striatal dopamine depletion, particularly in areas other than the sensorimotor striatum, compared to those with fewer non-motor symptoms.We conducted a prospective survey of the degree of non-motor symptoms (using the Korean version of the Non-Motor Symptoms Scale; K-NMSS in 151 patients with early-stage Parkinson's disease who had undergone a dopamine transporter PET scan as an initial diagnostic procedure. We classified the patients into two groups; high non-motor patients (HNM-PD; K-NMSS score ≥ 41 and low non-motor patients (LNM-PD.Patients in the HNM-PD group (n = 71 were older, had longer symptom duration, exhibited more severe motor deficits, and had been prescribed higher levodopa-equivalent doses at follow-up than those in the LNM-PD group. However, dopamine transporter binding to the striatal sub-regions and inter-sub-regional binding ratios were comparable between the two groups. A general linear model showed that the HNM-PD group had significantly more severe motor deficits than the LNM-PD group after controlling for age, gender, symptom duration, and dopamine transporter binding to the sensorimotor striatum.This study demonstrated that the pattern of striatal dopamine depletion does not contribute to early non-motor burden in Parkinson's disease. Our results suggest that LNM-PD patients may have a more benign course of motor symptom progression than HNM-PD patients.

  9. 41 CFR 101-26.501-9 - Centralized motor vehicle leasing program.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Centralized motor vehicle leasing program. 101-26.501-9 Section 101-26.501-9 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 26...

  10. 78 FR 25337 - Federal Aviation Administration

    Science.gov (United States)

    2013-04-30

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Agency Information Collection Activities: Requests for Comments; Clearance of Renewed Approval of Information Collection: Operations Specifications AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice and request for comments...

  11. 49 CFR 387.321 - Operations in foreign commerce.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Operations in foreign commerce. 387.321 Section 387.321 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER... Carriers and Property Brokers § 387.321 Operations in foreign commerce. No motor carrier may operate in the...

  12. 76 FR 80760 - Federal Implementation Plans for Iowa, Michigan, Missouri, Oklahoma, and Wisconsin and...

    Science.gov (United States)

    2011-12-27

    ... Determination for Kansas Regarding Interstate Transport of Ozone AGENCY: Environmental Protection Agency (EPA... Transport Rule (Federal Implementation Plans to Reduce Interstate Transport of Fine Particulate Matter and... in final rule: CFR Code of Federal Regulations EGU Electric Generating Unit FIP Federal...

  13. 49 CFR 583.10 - Outside suppliers of passenger motor vehicle equipment.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Outside suppliers of passenger motor vehicle... CONTENT LABELING § 583.10 Outside suppliers of passenger motor vehicle equipment. (a) For each unique type of passenger motor vehicle equipment for which a manufacturer or allied supplier requests information...

  14. 75 FR 35515 - Commercial Driver's License (CDL) Standards: Granting of Exemption; Volvo Trucks North America

    Science.gov (United States)

    2010-06-22

    ... Lundgren's driving under this exemption will maintain a level of safety equivalent to the level of safety... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2006... AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of final disposition...

  15. 77 FR 17105 - Commercial Driver's License (CDL) Standards; Rotel North American Tours, LLC; Application for...

    Science.gov (United States)

    2012-03-23

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2008... Renewal of Exemption; Correction AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION..., Rotel Tours, Das Rollende Hotel, through Georg Hoeltl GmBh & Co.Kg, Tittling, or George Hoeltl GmbH...

  16. 75 FR 30900 - Sunshine Act Meetings; Unified Carrier Registration Plan Board of Directors

    Science.gov (United States)

    2010-06-02

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration Sunshine Act Meetings; Unified Carrier Registration Plan Board of Directors AGENCY: Federal Motor Carrier Safety Administration... at the Hotel Park City, 2001 Park Avenue, Park City, UT 84060. Any interested person may call Mr...

  17. 76 FR 82179 - Drivers of CMVs: Restricting the Use of Cellular Phones

    Science.gov (United States)

    2011-12-30

    ... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration 49 CFR Part 390 Drivers of CMVs: Restricting the Use of Cellular Phones AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Final rule; correction. SUMMARY: FMCSA is correcting a Final Rule that appeared in...

  18. Riluzole increases the rate of glucose transport in L6 myotubes and NSC-34 motor neuron-like cells via AMPK pathway activation.

    Science.gov (United States)

    Daniel, Bareket; Green, Omer; Viskind, Olga; Gruzman, Arie

    2013-09-01

    Riluzole is the only approved ALS drug. Riluzole influences several cellular pathways, but its exact mechanism of action remains unclear. Our goal was to study the drug's influence on the glucose transport rate in two ALS relevant cell types, neurons and myotubes. Stably transfected wild-type or mutant G93A human SOD1 NSC-34 motor neuron-like cells and rat L6 myotubes were exposed to riluzole. The rate of glucose uptake, translocation of glucose transporters to the cell's plasma membrane and the main glucose transport regulatory proteins' phosphorylation levels were measured. We found that riluzole increases the glucose transport rate and up-regulates the translocation of glucose transporters to plasma membrane in both types of cells. Riluzole leads to AMPK phosphorylation and to the phosphorylation of its downstream target, AS-160. In conclusion, increasing the glucose transport rate in ALS affected cells might be one of the mechanisms of riluzole's therapeutic effect. These findings can be used to rationally design and synthesize novel anti-ALS drugs that modulate glucose transport in neurons and skeletal muscles.

  19. 49 CFR 396.5 - Lubrication.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS INSPECTION, REPAIR, AND MAINTENANCE § 396.5 Lubrication. Every motor carrier shall ensure that each motor vehicle subject to its control is...

  20. The role of transportation control measures in California's air pollution control strategy

    International Nuclear Information System (INIS)

    Guensler, R.; Burmich, P.; Geraghty, A.

    1992-01-01

    In California, significant progress has been made to control emissions from industrial sources as well as from motor vehicles. Nonetheless, policy analysts still debate over whether it makes sense to control motor vehicle emissions through legislated reductions in vehicle use, especially when new vehicle emission standards are becoming even more stringent in California. In this paper, the emission reduction benefits of California's new low-emission vehicles and clean fuels program are reviewed. The air quality management plans of three major metropolitan areas in California are examined, to identify emission reductions needed to meet federal and state air quality standards. For each of these three areas, emission reductions expected from transportation control measure implementation are presented. Then, the extent to which the reductions are open-quotes significantclose quotes and relied upon in each of the local attainment efforts is analyzed. The emission reductions expected from the stringent exhaust emission standards of California's new low-emission vehicles and clean fuels program will not be sufficient to meet mandated clean air standards in the study areas. Based upon our review, transportation control measures appear to be necessary components of the air quality management plans in California's major metropolitan areas. The paper concludes that cost-effective transportation control measures (TCMs) will be needed as a complementary strategy to California's stringent tail-pipe standards in moderate to extreme nonattainment areas

  1. Market Analysis and Consumer Impacts Source Document. Part II. Review of Motor Vehicle Market and Consumer Expenditures on Motor Vehicle Transportation

    Science.gov (United States)

    1980-12-01

    This source document on motor vehicle market analysis and consumer impacts consists of three parts. Part II consists of studies and review on: motor vehicle sales trends; motor vehicle fleet life and fleet composition; car buying patterns of the busi...

  2. 49 CFR 565.14 - Motor vehicles imported into the United States.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Motor vehicles imported into the United States...) REQUIREMENTS VIN Requirements § 565.14 Motor vehicles imported into the United States. (a) Importers shall utilize the VIN assigned by the original manufacturer of the motor vehicle. (b) All passenger cars...

  3. 49 CFR 583.11 - Allied suppliers of passenger motor vehicle equipment.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Allied suppliers of passenger motor vehicle... CONTENT LABELING § 583.11 Allied suppliers of passenger motor vehicle equipment. (a) For each unique type of passenger motor vehicle equipment which an allied supplier supplies to the manufacturer with which...

  4. 76 FR 48009 - Federal Motor Vehicle Safety Standards; Lamps, Reflective Devices, and Associated Equipment

    Science.gov (United States)

    2011-08-08

    ... (AAM), Ford Motor Company (Ford), Nissan North America (Nissan), Toyota Motor North America (Toyota... ``* * * of multiple compartment lamps or * * *''. Toyota requested that paragraph S14.3.1 be modified to use... photometric requirements of DRLs. Valeo claimed that there is no way to reconcile Table 1 of SAE J222 (DEC...

  5. 76 FR 2745 - Federal Aviation Administration

    Science.gov (United States)

    2011-01-14

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Eighty-Fourth Meeting: RTCA Special Committee 159: Global Positioning System (GPS) AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 159 meeting: Global Positioning System (GPS). SUMMARY: The FAA is...

  6. Purchasing motors under consideration of full-cost pricing

    International Nuclear Information System (INIS)

    Mauchle, P.; Ritz, Ch.

    2007-01-01

    This final report for the Swiss Federal Office of Energy (SFOE) takes a look at how full-cost pricing should be considered when purchasing electric motors. The authors consider it essential that the overall life-cycle costs are carefully considered. This also guarantees economical operation and enables users to avoid unexpected costs throughout the service life of the motor. The aim of this project was to provide industrial companies with suitable tools for calculating the overall life-cycle costs of motors at the time of their acquisition. These tools take the form of a sample 'Call for Tender' for motors along with software for calculating life-cycle costs. The factors involved, such as investment, installation costs, energy and environmental costs as well as operational, maintenance and disposal costs are examined.

  7. Motor protein traffic regulation by supply–demand balance of resources

    International Nuclear Information System (INIS)

    Ciandrini, Luca; Dauloudet, Olivier; Parmeggiani, Andrea; Neri, Izaak; Walter, Jean Charles

    2014-01-01

    In cells and in in vitro assays the number of motor proteins involved in biological transport processes is far from being unlimited. The cytoskeletal binding sites are in contact with the same finite reservoir of motors (either the cytosol or the flow chamber) and hence compete for recruiting the available motors, potentially depleting the reservoir and affecting cytoskeletal transport. In this work we provide a theoretical framework in which to study, analytically and numerically, how motor density profiles and crowding along cytoskeletal filaments depend on the competition of motors for their binding sites. We propose two models in which finite processive motor proteins actively advance along cytoskeletal filaments and are continuously exchanged with the motor pool. We first look at homogeneous reservoirs and then examine the effects of free motor diffusion in the surrounding medium. We consider as a reference situation recent in vitro experimental setups of kinesin-8 motors binding and moving along microtubule filaments in a flow chamber. We investigate how the crowding of linear motor proteins moving on a filament can be regulated by the balance between supply (concentration of motor proteins in the flow chamber) and demand (total number of polymerized tubulin heterodimers). We present analytical results for the density profiles of bound motors and the reservoir depletion, and propose novel phase diagrams that present the formation of jams of motor proteins on the filament as a function of two tuneable experimental parameters: the motor protein concentration and the concentration of tubulins polymerized into cytoskeletal filaments. Extensive numerical simulations corroborate the analytical results for parameters in the experimental range and also address the effects of diffusion of motor proteins in the reservoir. We then propose experiments for validating our models and discuss how the ‘supply–demand’ effects can regulate motor traffic also in in vivo

  8. 49 CFR 571.125 - Standard No. 125; Warning devices.

    Science.gov (United States)

    2010-10-01

    ... TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR VEHICLE SAFETY STANDARDS Federal... in motor vehicles and used to warn approaching traffic of the presence of a stopped vehicle, except... the driver activate the vehicular hazard warning signal lamps before leaving the vehicle to erect the...

  9. Engineering solutions of traffic safety problems of road transport

    Directory of Open Access Journals (Sweden)

    M. Bogdevičius

    2004-02-01

    Full Text Available The authors of this paper focus on the simulation of the motor vehicle movement (taking into consideration motor vehicle dynamics, motor vehicle hydraulic brake system influence on motor vehicle movement, interaction between its wheels with road pavements, road guardrail characteristics, interaction between motor vehicle and road guardrail on a certain road section and propose their specific solution of this problem. The presented results, illustrating the motor vehicle movement trajectories (motor vehicle braking and interaction between motor vehicle and road guardrail at various initial conditions and at various certain pavement surface of the road section under investigation and work of a motor vehicle hydraulic brake system. Taking into consideration the presented general mathematical model and computer aided test results it is possible to investigate various road transport traffic situations as well as to investigate various transport traffic safety problems.

  10. Lateralization of cortical negative motor areas.

    Science.gov (United States)

    Borggraefe, Ingo; Catarino, Claudia B; Rémi, Jan; Vollmar, Christian; Peraud, Aurelia; Winkler, Peter A; Noachtar, Soheyl

    2016-10-01

    The lateral and mesial aspects of the central and frontal cortex were studied by direct electrical stimulation of the cortex in epilepsy surgery candidates in order to determine the localization of unilateral and bilateral negative motor responses. Results of electrical cortical stimulation were examined in epilepsy surgery candidates in whom invasive electrodes were implanted. The exact localization of subdural electrodes was defined by fusion of 3-dimensional reconstructed MRI and CT images in 13 patients and by analysis of plane skull X-rays and intraoperative visual localization of the electrodes in another 7 patients. Results of electrical stimulation of the cortex were evaluated in a total of 128 patients in whom invasive electrodes were implanted for planning resective epilepsy surgery. Twenty patients, in whom negative motor responses were obtained, were included in the study. Bilateral upper limb negative motor responses were more often elicited from stimulation of the mesial frontal cortex whereas stimulation of the lateral central cortex leads to contralateral upper limb negative motor responses (pfrontal gyrus whereas contralateral negative motor responses localized predominantly in the anterior part of the precentral gyrus (pgyrus and the mesial fronto-central cortex showing functional differences with regard to unilateral and bilateral upper limb representation. The lateral fronto-central negative motor area serves predominantly contralateral upper limb motor control whereas the mesial frontal negative motor area represents bilateral upper limb movement control. Copyright © 2016 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  11. 23 CFR 710.601 - Federal land transfer.

    Science.gov (United States)

    2010-04-01

    ... FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT RIGHT-OF-WAY AND REAL ESTATE Federal Assistance Programs § 710.601 Federal land transfer. (a) The provisions of this... agency will be notified and a right-of-entry requested. The land-owning agency shall have a period of...

  12. Alternatives to traditional transportation fuels: An overview

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    This report presents the first compilation by the Energy Information Administration (EIA) of information on alternatives to gasoline and diesel fuel. The purpose of the report is: (1) to provide background information on alternative transportation fuels and replacement fuels compared with gasoline and diesel fuel, and (2) to furnish preliminary estimates of alternative transportation fuels and alternative fueled vehicles as required by the Energy Policy Act of 1992 (EPACT), Title V, Section 503, ``Replacement Fuel Demand Estimates and Supply Information.`` Specifically, Section 503 requires the EIA to report annually on: (1) the number and type of alternative fueled vehicles in existence the previous year and expected to be in use the following year, (2) the geographic distribution of these vehicles, (3) the amounts and types of replacement fuels consumed, and (4) the greenhouse gas emissions likely to result from replacement fuel use. Alternative fueled vehicles are defined in this report as motorized vehicles licensed for on-road use, which may consume alternative transportation fuels. (Alternative fueled vehicles may use either an alternative transportation fuel or a replacement fuel.) The intended audience for the first section of this report includes the Secretary of Energy, the Congress, Federal and State agencies, the automobile manufacturing industry, the transportation fuel manufacturing and distribution industries, and the general public. The second section is designed primarily for persons desiring a more technical explanation of and background for the issues surrounding alternative transportation fuels.

  13. 49 CFR 565.24 - Motor vehicles imported into the United States.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Motor vehicles imported into the United States...) REQUIREMENTS Alternative VIN Requirements In Effect for Limited Period § 565.24 Motor vehicles imported into... motor vehicle. (b) A passenger car certified by a Registered Importer under 49 CFR part 592 shall have a...

  14. Fault diagnosis of induction motors

    CERN Document Server

    Faiz, Jawad; Joksimović, Gojko

    2017-01-01

    This book is a comprehensive, structural approach to fault diagnosis strategy. The different fault types, signal processing techniques, and loss characterisation are addressed in the book. This is essential reading for work with induction motors for transportation and energy.

  15. 49 CFR 374.317 - Identification-bus and driver.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Identification-bus and driver. 374.317 Section 374... SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS PASSENGER CARRIER REGULATIONS Adequacy of Intercity Motor Common Carrier Passenger Service § 374.317 Identification...

  16. 77 FR 14482 - Petroleum Reduction and Alternative Fuel Consumption Requirements for Federal Fleets

    Science.gov (United States)

    2012-03-12

    ...-road or non-road vehicle. \\2\\ The definition of the term ``low-speed electric vehicle,'' as used... alternative fuel used in Federal fleet motor vehicles. This report also would include the alternative fuel...-- (1) a motor vehicle that operates solely on alternative fuel; or (2) a low-speed electric vehicle. (g...

  17. Guide to federal intelligent transportation system (ITS) research.

    Science.gov (United States)

    2013-01-01

    The U.S. Department of Transportations (USDOT) Intelligent Transportation System (ITS) Program aims to bring connectivity to transportation through the use of advanced wireless technologies powerful technologies that enable transformative chan...

  18. 49 CFR 592.9 - Forfeiture of bond.

    Science.gov (United States)

    2010-10-01

    ... Federal motor vehicle safety, bumper, and theft prevention standard in effect at the time the vehicle was... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) REGISTERED IMPORTERS OF VEHICLES NOT ORIGINALLY MANUFACTURED TO CONFORM TO THE FEDERAL MOTOR VEHICLE SAFETY STANDARDS § 592.9 Forfeiture of bond. A Registered...

  19. Synchronous motor with HTS-2G wires

    Science.gov (United States)

    Dezhin, D.; Ilyasov, R.; Kozub, S.; Kovalev, K.; Verzhbitsky, L.

    2014-05-01

    One of the applications of new high-temperature superconductor materials (HTS) is field coils for synchronous electrical machines. The use of YBCO 2G HTS tapes (HTS-2G) allows increasing of magnetic flux density in the air gap, which will increase the output power and reduce the dimensions of the motor. Such motors with improved characteristics can be successfully used in transportation as traction motor. In MAI-based "Center of Superconducting machines and devices" with the support of "Rosatom" has been designed and tested a prototype of the 50 kW synchronous motor with radial magnetic flux from a field-coils based on HTS-2G tapes. The experimental and theoretical results are presented.

  20. 23 CFR 772.13 - Federal participation.

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Federal participation. 772.13 Section 772.13 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT PROCEDURES FOR... noise barriers (including landscaping for aesthetic purposes) whether within or outside the highway...

  1. Dollar Summary of Federal Supply Classification and Service Category by Company, FY83, Part 1 (1005-5811).

    Science.gov (United States)

    1983-01-01

    E STATE TOTAL 590 LEAR S b1 . . . . • I . i I I I . DEPARTMENT OF DEFENSE PAGE 381 PRIME CONTRACTS OVER $25. 000 BY FEDERAL STOCK CLASSIFICATION...MOTOR VEHICLE MAINTENANCE EQUIPMENT 94 RONAN & KUNZL INC MICHIGAN ARMY MOTOR VEHICLE MAINTENANCE EQUIPMENT C9 RUGBY INDUSTRIES INC MINNESOTA ARMY MOTOR

  2. Cytoskeleton Molecular Motors: Structures and Their Functions in Neuron.

    Science.gov (United States)

    Xiao, Qingpin; Hu, Xiaohui; Wei, Zhiyi; Tam, Kin Yip

    2016-01-01

    Cells make use of molecular motors to transport small molecules, macromolecules and cellular organelles to target region to execute biological functions, which is utmost important for polarized cells, such as neurons. In particular, cytoskeleton motors play fundamental roles in neuron polarization, extension, shape and neurotransmission. Cytoskeleton motors comprise of myosin, kinesin and cytoplasmic dynein. F-actin filaments act as myosin track, while kinesin and cytoplasmic dynein move on microtubules. Cytoskeleton motors work together to build a highly polarized and regulated system in neuronal cells via different molecular mechanisms and functional regulations. This review discusses the structures and working mechanisms of the cytoskeleton motors in neurons.

  3. Using in-depth investigations to identify transportation safety issues for wheelchair-seated occupants of motor vehicles.

    Science.gov (United States)

    Schneider, Lawrence W; Klinich, Kathleen D; Moore, Jamie L; MacWilliams, Joel B

    2010-04-01

    In-depth investigations of motor-vehicle crashes involve detailed inspection, measurement, and photodocumentation of vehicle exterior and interior damage, evidence of belt-restraint use, and evidence of occupant contacts with the vehicle interior. Results of in-depth investigations thereby provide the most objective way to identify current and emerging injury problems and issues in occupant safety and crash protection, and provide important feedback on the real-world performance of the latest restraint-system and vehicle crashworthiness technologies. To provide an objective understanding of real-world transportation safety issues for wheelchair-seated travelers, the University of Michigan Transportation Research Institute (UMTRI) has been conducting and assembling data from in-depth investigations of motor-vehicle crashes and non-crash adverse moving-vehicle incidents, such as emergency vehicle braking, turning, and swerving, in which there was at least one vehicle occupant sitting in a wheelchair. The results of 39 investigations involving 42 wheelchair-seated occupants have been assembled and entered into a wheelchair-occupant crash/injury database. In addition, a biomechanical analysis of each case has been performed to identify key safety issues for wheelchair-seated travelers. The wheelchairs of 34 of the 42 occupants who were seated in wheelchairs while traveling in motor vehicles were effectively secured by either a four-point, strap-type tiedown system or a docking securement device, and all but one of these properly secured wheelchairs remained in place during the crash or non-collision event. However, 30 of the 42 occupants were improperly restrained, either because of non-use or incomplete use of available belt restraints, or because the belt restraints were improperly positioned on the occupant's body. Twenty-six of the 42 occupants sustained significant injuries and 10 of these occupants died as a direct result of injuries sustained, or from

  4. National Motor Vehicle Crash Causation Survey (NMVCCS)

    Data.gov (United States)

    Department of Transportation — The National Motor Vehicle Crash Causation Survey (NMVVCS) was a nationwide survey of crashes involving light passenger vehicles, with a focus on the factors related...

  5. 49 CFR 392.11 - Railroad grade crossings; slowing down required.

    Science.gov (United States)

    2010-10-01

    ... MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS DRIVING OF COMMERCIAL MOTOR VEHICLES Driving of Commercial Motor Vehicles § 392.11 Railroad grade..., upon approaching a railroad grade crossing, be driven at a rate of speed which will permit said...

  6. 49 CFR Appendix A to Part 604 - Listing of Human Service Federal Financial Assistance Programs

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Listing of Human Service Federal Financial... (Continued) FEDERAL TRANSIT ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CHARTER SERVICE Pt. 604, App. A Appendix A to Part 604—Listing of Human Service Federal Financial Assistance Programs Federal Programs...

  7. A novel linear switched reluctance motor for railway transportation systems

    International Nuclear Information System (INIS)

    Daldaban, Ferhat; Ustkoyuncu, Nurettin

    2010-01-01

    This paper presents the design and realization of a new linear switched reluctance motor (LSRM) structure, especially suitable for high-speed railway systems. The new model has a double active stator configuration and provides high force for many applications with low cost. The characteristics of the LSRM are obtained by using finite element analysis (FEA) and analytical calculations. The results of the FEA and analytical calculations are presented, and compared with experimental results. In addition, a classical double-sided LSRM (DSLSRM) is modeled with the same specifications of the new motor structure and the results are compared.

  8. The effect of outsourcing and situational characteristics on physical distribution transportation efficiency

    OpenAIRE

    Bienstock, Carol C

    1994-01-01

    This research examined the outsourcing decision for the logistics function of motor carrier transportation. A full factorial design was executed on a simulated transportation network to investigate how the efficiency of motor carrier transportation was affected by how it was structured (private/leased fleet versus contract carrier transportation) and the characteristics of the transportation activities. Transaction Cost Analysis (TCA) offered a useful theoretical framework for consideration o...

  9. 14 CFR 1204.1600 - Issuance of motor vehicle for home-to-work.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Issuance of motor vehicle for home-to-work... ADMINISTRATIVE AUTHORITY AND POLICY Temporary Duty Travel-Issuance of Motor Vehicle for Home-to-Work Transportation § 1204.1600 Issuance of motor vehicle for home-to-work. When a NASA employee on temporary duty...

  10. 77 FR 20486 - Petition for Exemption From the Vehicle Theft Prevention Standard; Mitsubishi Motors

    Science.gov (United States)

    2012-04-04

    ... From the Vehicle Theft Prevention Standard; Mitsubishi Motors AGENCY: National Highway Traffic Safety... exemption of the Mitsubishi i-MiEV vehicle line in accordance with 49 CFR part 543, Exemption From the Theft... motor vehicle theft as compliance with the parts-marking requirements of the 49 CFR part 541, Federal...

  11. 49 CFR 172.701 - Federal-State relationship.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Federal-State relationship. 172.701 Section 172... TABLE, SPECIAL PROVISIONS, HAZARDOUS MATERIALS COMMUNICATIONS, EMERGENCY RESPONSE INFORMATION, TRAINING REQUIREMENTS, AND SECURITY PLANS Training § 172.701 Federal-State relationship. This subpart and the parts...

  12. 48 CFR 47.306-2 - Lowest overall transportation costs.

    Science.gov (United States)

    2010-10-01

    ... transportation costs. 47.306-2 Section 47.306-2 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TRANSPORTATION Transportation in Supply Contracts 47.306-2 Lowest overall transportation costs. (a) For the evaluation of offers, the transportation officer shall give to the contracting...

  13. 77 FR 29247 - Federal Motor Vehicle Safety Standards; Occupant Crash Protection

    Science.gov (United States)

    2012-05-17

    ...). On January 25, 2005, we received a request for interpretation from Toyota Motor North America, Inc. (Toyota) concerning S4.5.1(e).\\5\\ Toyota's concern was that S4.5.1(e)(1) makes an exception for S4.5.1(e... vehicles certified to meet certain advanced air bag requirements on or after December 1, 2003. Toyota...

  14. Energy transport corridors: the potential role of Federal lands in states identified by the Energy Policy Act of 2005, section 368(b).

    Energy Technology Data Exchange (ETDEWEB)

    Krummel, J.; Hlohowskyj, I.; Kuiper, J.; Kolpa, R.; Moore, R.; May, J.; VanKuiken, J.C.; Kavicky, J.A.; McLamore, M.R.; Shamsuddin, S. (Decision and Information Sciences); ( EVS)

    2011-09-01

    On August 8, 2005, the President signed the Energy Policy Act of 2005 (EPAct) into law. In Subtitle F of EPAct, Congress set forth various provisions that would change the way certain federal agencies (Agencies) coordinate to authorize the use of land for a variety of energy-related purposes. As part of Subtitle F of EPAct, Section 368 addresses the issue of energy transportation corridors on federal land for oil, gas, and hydrogen pipelines, as well as electricity transmission and distribution facilities. Because of the critical importance of improving the nation's electrical transmission grid, Congress recognized that electricity transmission issues should receive added attention when the Agencies address corridor location and analysis issues. In Section 368, Congress specifically directed the Agencies to consider the need for upgraded and new facilities to deliver electricity: In carrying out [Section 368], the Secretaries shall take into account the need for upgraded and new electricity transmission and distribution facilities to (1) improve reliability; (2) relieve congestion; and (3) enhance capability of the national grid to deliver electricity. Section 368 does not require the Agencies to consider or approve specific projects, applications for rights-of-way (ROWs), or other permits within designated energy corridors. Importantly, Section 368 does not direct, license, or otherwise permit any on-the-ground activity of any sort. If an applicant is interested in obtaining an authorization to develop a project within any corridor designated under Section 368, the applicant would have to apply for a ROW authorization and applicable permits. The Agencies would consider each application by applying appropriate project-specific reviews under requirements of laws and related regulations, including, but not limited to, the National Environmental Policy Act (NEPA), the Clean Water Act, the Clean Air Act, Section 7 of the Endangered Species Act (ESA), and Section

  15. US military expenditures to protect the use of Persian Gulf oil for motor vehicles

    International Nuclear Information System (INIS)

    Delucchi, Mark A.; Murphy, James J.

    2008-01-01

    Analyses of the full social cost of motor vehicle use in the US often estimate an 'oil import premium' that includes the military cost of defending oil supplies from the Persian Gulf. Estimates of this cost have ranged from essentially zero to upwards of a $1 per gallon (about $0.25 per liter). In this paper, we attempt to narrow this range, by carefully answering the question: 'If the US highway transportation sector did not use oil, how much would the US federal government reduce its military commitment in the Persian Gulf?' We work towards our answer in five steps, accounting for interests not related to oil, the interests of other oil-consuming countries, the interests of producers apart from the interests of consumers, and the interests of non-highway users of oil. We estimate that were there no oil in the Persian Gulf, then US combined peacetime and wartime defense expenditures might be reduced in the long run by roughly $27-$73 billion per year (in 2004 dollars), of which roughly $6-$25 billion annually ($0.03-$0.15 per gallon or $0.01-$0.04 per liter) is attributable to motor-vehicle use

  16. Motor unit number estimation in the quantitative assessment of severity and progression of motor unit loss in Hirayama disease.

    Science.gov (United States)

    Zheng, Chaojun; Zhu, Yu; Zhu, Dongqing; Lu, Feizhou; Xia, Xinlei; Jiang, Jianyuan; Ma, Xiaosheng

    2017-06-01

    To investigate motor unit number estimation (MUNE) as a method to quantitatively evaluate severity and progression of motor unit loss in Hirayama disease (HD). Multipoint incremental MUNE was performed bilaterally on both abductor digiti minimi and abductor pollicis brevis muscles in 46 patients with HD and 32 controls, along with handgrip strength examination. MUNE was re-evaluated approximately 1year after initial examination in 17 patients with HD. The MUNE values were significantly lower in all the tested muscles in the HD group (Pdisease duration (Pmotor unit loss in patients with HD within approximately 1year (P4years. A reduction in the functioning motor units was found in patients with HD compared with that in controls, even in the early asymptomatic stages. Moreover, the motor unit loss in HD progresses gradually as the disease advances. These results have provided evidence for the application of MUNE in estimating the reduction of motor unit in HD and confirming the validity of MUNE for tracking the progression of HD in a clinical setting. Copyright © 2017 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.

  17. 49 CFR 545.3 - Applicability.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR VEHICLE THEFT PREVENTION STANDARD PHASE-IN AND SMALL-VOLUME LINE REPORTING REQUIREMENTS § 545.3 Applicability. This subpart applies to manufacturers of motor vehicles. ...

  18. Chemical and thermal modulation of molecular motor activities

    Science.gov (United States)

    Hong, Weili

    Molecular motors of kinesin and dynein families are responsible for various intracellular activities, from long distance movement of organelles, vesicles, protein complexes, and mRNAs to powering mitotic processes. They can take nanometer steps using chemical energy from the hydrolysis of ATP (adenosine triphosphate), and their dysfunction is involved in many neurodegenerative diseases that require long distance transport of cargos. Here I report on the study of the properties of molecular motors at a single-molecule level using optical trappings. I first studied the inhibition properties of kinesin motors by marine natural compound adociasulfates. I showed that adociasulfates compete with microtubules for binding to kinesins and thus inhibit kinesins' activity. Although adociasulfates are a strong inhibitor for all kinesin members, they show a much higher inhibition effect for conventional kinesins than for mitotic kinesins. Thus adociasulfates can be used to specifically inhibit conventional kinesins. By comparing the inhibition of kinesins by two structurally similar adociasulfates, one can see that the negatively charged sulfate residue of adociasulfates can be replaced by other negative residues and thus make it possible for adociasulfate-derived compounds to be more cell permeable. Kinesins and dyneins move cargos towards opposite directions along a microtubule. Cargos with both kinesins and dyneins attached often move bidirectionally due to undergoing a tug-of-war between the oppositely moving kinesin and dynein motors. Here I studied the effect of temperature on microtubule-based kinesin and dynein motor transport. While kinesins' and dyneins' velocities are closely matched above 15 °C, below this temperature the dyneins' velocity decreases much faster than the kinesins'. The kinesins' and dyneins' forces do not measurably change with temperature. The results suggest that temperature has significant effects on bidirectional transport and can be used to

  19. Continuous growth of the motor system in the axolotl

    International Nuclear Information System (INIS)

    Holder, N.; Clarke, J.D.; Stephens, N.; Wilson, S.W.; Orsi, C.; Bloomer, T.; Tonge, D.A.

    1991-01-01

    During growth of the axolotl, motor neurons, and muscle fibres are added to the motor system. By double labelling neurons with tritiated thymidine and retrogradely transported HRP, we show that some motor neurons are born at postembryonic stages. Further analysis of motor neurons with the aid of HRP reveals this population of newly born cells relatively frequently in small (5-7 cm long) axolotls, but only rarely in large (7-13 cm long) axolotls. Evidence is presented that suggests that these immature cells are in the process of migrating from close to the ependyma out to the ventral horn. HRP transport also reveals growth cones of advancing axons within spinal nerves in animals up to 6 cm in length. Cell counts by light and electron microscopic methods show that muscle fibres are generated throughout larval life in the iliotibialis, a typical limb muscle. This analysis provides data consistent with the notion that new muscle fibres are added from a localised growth zone situated at the superficial edge of the muscle. These results are discussed in terms of the correlation between continuous growth of the motor system and the ability of the axolotl to functionally repair lesions to the peripheral nervous system

  20. High-order motor cortex in rats receives somatosensory inputs from the primary motor cortex via cortico-cortical pathways.

    Science.gov (United States)

    Kunori, Nobuo; Takashima, Ichiro

    2016-12-01

    The motor cortex of rats contains two forelimb motor areas; the caudal forelimb area (CFA) and the rostral forelimb area (RFA). Although the RFA is thought to correspond to the premotor and/or supplementary motor cortices of primates, which are higher-order motor areas that receive somatosensory inputs, it is unknown whether the RFA of rats receives somatosensory inputs in the same manner. To investigate this issue, voltage-sensitive dye (VSD) imaging was used to assess the motor cortex in rats following a brief electrical stimulation of the forelimb. This procedure was followed by intracortical microstimulation (ICMS) mapping to identify the motor representations in the imaged cortex. The combined use of VSD imaging and ICMS revealed that both the CFA and RFA received excitatory synaptic inputs after forelimb stimulation. Further evaluation of the sensory input pathway to the RFA revealed that the forelimb-evoked RFA response was abolished either by the pharmacological inactivation of the CFA or a cortical transection between the CFA and RFA. These results suggest that forelimb-related sensory inputs would be transmitted to the RFA from the CFA via the cortico-cortical pathway. Thus, the present findings imply that sensory information processed in the RFA may be used for the generation of coordinated forelimb movements, which would be similar to the function of the higher-order motor cortex in primates. © 2016 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  1. Electrical energy saving in motors and frequency variators; Ahorro de energia electrica en motores y variadores de frecuencia

    Energy Technology Data Exchange (ETDEWEB)

    Garcia Neri, Roger [Comision Federal de Electricidad (CFE) (Mexico)

    2005-07-01

    The necessity of saving energy is urgent and undeniable. We must already begin with the rational use of energy. Which is obtaining the maximum benefit of the consumed energy and of the necessary facilities for its generation, transmission and use. Guaranteeing at the same time an operation free of interferences or interruptions for the users. The electricity in alternating current does not allow its storage, reason why it is necessary to generate and distribute it at the precise moment when it is required. This forces to determine the proportions of the generation facilities, to be able to feed the periods of maximum demand called {sup p}eaks{sup .} It is this very point where the problem of the inappropriate use of the electrical energy starts. The energy waste is self-evident during the periods of low demand because of the low efficiency of the sub-utilized facilities. Electrical motors of the induction type use approximately more than 60% of the energy in the industry. If we use high efficiency motors instead of standard motors, a better advantage of the energy demanded from Comision Federal de Electricidad (CFE) is obtained. [Spanish] Es impostergable e innegable la necesidad de ahorrar energia. Tenemos que empezar ya con el uso racional de la energia: Obtener el maximo beneficio de la energia consumida y de las instalaciones necesarias para su generacion, transmision y utilizacion. Garantizando a los usuarios un funcionamiento sin interferencias o interrupciones. La electricidad en corriente alterna no permite su almacenamiento, por lo que es necesario generarla y distribuirla en el momento preciso en que es requerida. Esto obliga a dimensionar las instalaciones de generacion, para poder alimentar los periodos de maxima demanda llamados pico. Desde esta parte inicia el problema de la mala utilizacion de la energia electrica. Ya que en los periodos de baja demanda, las instalaciones se encuentran subutilizadas y si su eficiencia es muy baja, el desperdicio de

  2. 77 FR 66501 - General Motors, LLC, Receipt of Petition for Decision of Inconsequential Noncompliance

    Science.gov (United States)

    2012-11-05

    ... motor vehicle safety for the following reasons: (1) The functionality of all braking systems, including... paragraph S5.2.1 of Federal Motor Vehicle Safety Standard (FMVSS) No. 101, Controls and Displays and paragraphs S5.5.5 of FMVSS No. 135, Light Vehicle Brake Systems. GM has filed an appropriate report pursuant...

  3. Neurofeedback training of alpha-band coherence enhances motor performance.

    Science.gov (United States)

    Mottaz, Anais; Solcà, Marco; Magnin, Cécile; Corbet, Tiffany; Schnider, Armin; Guggisberg, Adrian G

    2015-09-01

    Neurofeedback training of motor cortex activations with brain-computer interface systems can enhance recovery in stroke patients. Here we propose a new approach which trains resting-state functional connectivity associated with motor performance instead of activations related to movements. Ten healthy subjects and one stroke patient trained alpha-band coherence between their hand motor area and the rest of the brain using neurofeedback with source functional connectivity analysis and visual feedback. Seven out of ten healthy subjects were able to increase alpha-band coherence between the hand motor cortex and the rest of the brain in a single session. The patient with chronic stroke learned to enhance alpha-band coherence of his affected primary motor cortex in 7 neurofeedback sessions applied over one month. Coherence increased specifically in the targeted motor cortex and in alpha frequencies. This increase was associated with clinically meaningful and lasting improvement of motor function after stroke. These results provide proof of concept that neurofeedback training of alpha-band coherence is feasible and behaviorally useful. The study presents evidence for a role of alpha-band coherence in motor learning and may lead to new strategies for rehabilitation. Copyright © 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  4. 48 CFR 847.306-70 - Transportation payment and audit.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Transportation payment and audit. 847.306-70 Section 847.306-70 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS CONTRACT MANAGEMENT TRANSPORTATION Transportation in Supply Contracts 847.306-70 Transportation payment and audit. Transportation payments ar...

  5. Mechanical design of translocating motor proteins.

    Science.gov (United States)

    Hwang, Wonmuk; Lang, Matthew J

    2009-01-01

    Translocating motors generate force and move along a biofilament track to achieve diverse functions including gene transcription, translation, intracellular cargo transport, protein degradation, and muscle contraction. Advances in single molecule manipulation experiments, structural biology, and computational analysis are making it possible to consider common mechanical design principles of these diverse families of motors. Here, we propose a mechanical parts list that include track, energy conversion machinery, and moving parts. Energy is supplied not just by burning of a fuel molecule, but there are other sources or sinks of free energy, by binding and release of a fuel or products, or similarly between the motor and the track. Dynamic conformational changes of the motor domain can be regarded as controlling the flow of free energy to and from the surrounding heat reservoir. Multiple motor domains are organized in distinct ways to achieve motility under imposed physical constraints. Transcending amino acid sequence and structure, physically and functionally similar mechanical parts may have evolved as nature's design strategy for these molecular engines.

  6. 76 FR 42160 - Commercial Space Transportation Advisory Committee-Public Teleconference

    Science.gov (United States)

    2011-07-18

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Commercial Space Transportation Advisory Committee--Public Teleconference AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Space Transportation Operations Working Group of the Commercial Space Transportation Advisory...

  7. Environment issues and the future of the transport industry

    Energy Technology Data Exchange (ETDEWEB)

    Shiller, J W [Ford Motor Company, Dearborn, MI (USA)

    1992-01-01

    The motor vehicle industry must make the necessary investment in products and technology to meet the competitive and environmental challenges of the future. Discussion is presented of: the history of motor vehicles, the relationship of motor vehicles to the environment, the state of climate change knowledge, future economic development and the transport sector, the changing structure of the motor vehicle fleet, traffic congestion, alternative fuels, investments in transport, the European Energy Charter, The US Energy Strategy, the North American free trade agreement, and the economics of the automobile industry in Japan/South East Asia and the developing countries. 61 refs., 29 figs., 28 tabs.

  8. Series hybrid vehicle system analysis using an in-wheel motor design

    NARCIS (Netherlands)

    Paulides, J.J.H.; Kazmin, Evgeny; Gysen, B.L.J.; Lomonova, E.

    2008-01-01

    Hybrid vehicles, which employ a technology combining gasoline and electric motors, are a hot item these days for transporters looking for ways to cut their fuel bills. To date, commercial systems implement diesel assisted electrical drives. As such the electrical motor is placed in a series or

  9. Sustainability Aspects of Energy Conversion in Modern High-Speed Trains with Traction Induction Motors

    OpenAIRE

    Marc A. Rosen; Doru A. Nicola; Cornelia A. Bulucea; Daniel C. Cismaru

    2015-01-01

    Some aspects are illustrated of energy conversion processes during the operation of electric railway vehicles with traction induction motors, in order to support transport systems’ sustainability. Increasing efforts are being expended to enhance the sustainability of transportation technologies and systems. Since electric drive systems are used with variable voltage variable frequency (VVVF) inverters and traction induction motors, these machines with appropriate controls can realize both tra...

  10. 49 CFR 835.10 - Testimony in Federal, State, or local criminal investigations and other proceedings.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Testimony in Federal, State, or local criminal investigations and other proceedings. 835.10 Section 835.10 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL TRANSPORTATION SAFETY BOARD TESTIMONY OF BOARD EMPLOYEES § 835.10 Testimony in Federal, State, or local crimina...

  11. 41 CFR 102-34.300 - How do we dispose of a domestic fleet motor vehicle?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false How do we dispose of a domestic fleet motor vehicle? 102-34.300 Section 102-34.300 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION PERSONAL PROPERTY...

  12. A Bayesian reliability study on motorized valves for the emergency core cooling, heat transport isolation and shutdown cooling systems at Gentilly-2 Nuclear Generating Station

    International Nuclear Information System (INIS)

    Smith, J.E.; Rennick, D.F.; Nainer, A.

    1996-01-01

    The objective of this is to examine operational data on 32 motorized valves in the emergency core cooling, shutdown cooling and heat transport isolation systems and determine if the evidence would support a reduction in testing frequency of these valves. The methodology used is to examine the data which has accumulated on motorized valve failures since Gentilly-2 first entered service, compare these data with similar data from other sources, and determine whether the evidence indicate that demand-based, wear out type failure mechanisms play a significant role in the recorded failures. The statistical data are then updated, using a Bayesian updating procedure, to obtain revised time based failure rates and demand based probabilities of failure on demand for the motorized valves. The revised failure rates and probabilities are then applied to the fault tree models for the systems of interest to determine what effects there would be, with the current test intervals and with extended test intervals, on the probability of failure of the systems. (author)

  13. 77 FR 71474 - Commercial Space Transportation Advisory Committee-Charter Renewal

    Science.gov (United States)

    2012-11-30

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Commercial Space Transportation... Transportation (DOT). ACTION: Announcement of Charter Renewal of the Commercial Space Transportation Advisory... Administrator of the Federal Aviation Administration (FAA) on the critical matters facing the U.S. commercial...

  14. Use of unmanned aerial vehicles for medical product transport.

    Science.gov (United States)

    Thiels, Cornelius A; Aho, Johnathon M; Zietlow, Scott P; Jenkins, Donald H

    2015-01-01

    Advances in technology and decreasing costs have led to an increased use of unmanned aerial vehicles (UAVs) by the military and civilian sectors. The use of UAVs in commerce is restricted by US Federal Aviation Administration (FAA) regulations, but the FAA is drafting new regulations that are expected to expand commercial applications. Currently, the transportation of medical goods in times of critical need is limited to wheeled motor vehicles and manned aircraft, options that can be costly and slow. This article explores the demand for, feasibility of, and risks associated with the use of UAVs to deliver medical products, including blood derivatives and pharmaceuticals, to hospitals, mass casualty scenes, and offshore vessels in times of critical demand. Copyright © 2015 Air Medical Journal Associates. Published by Elsevier Inc. All rights reserved.

  15. Saxton Transportation Operations Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Saxton Transportation Operations Laboratory (Saxton Laboratory) is a state-of-the-art facility for conducting transportation operations research. The laboratory...

  16. Handbook of high-level radioactive waste transportation

    International Nuclear Information System (INIS)

    Sattler, L.R.

    1992-10-01

    The High-Level Radioactive Waste Transportation Handbook serves as a reference to which state officials and members of the general public may turn for information on radioactive waste transportation and on the federal government's system for transporting this waste under the Civilian Radioactive Waste Management Program. The Handbook condenses and updates information contained in the Midwestern High-Level Radioactive Waste Transportation Primer. It is intended primarily to assist legislators who, in the future, may be called upon to enact legislation pertaining to the transportation of radioactive waste through their jurisdictions. The Handbook is divided into two sections. The first section places the federal government's program for transporting radioactive waste in context. It provides background information on nuclear waste production in the United States and traces the emergence of federal policy for disposing of radioactive waste. The second section covers the history of radioactive waste transportation; summarizes major pieces of legislation pertaining to the transportation of radioactive waste; and provides an overview of the radioactive waste transportation program developed by the US Department of Energy (DOE). To supplement this information, a summary of pertinent federal and state legislation and a glossary of terms are included as appendices, as is a list of publications produced by the Midwestern Office of The Council of State Governments (CSG-MW) as part of the Midwestern High-Level Radioactive Waste Transportation Project

  17. Synaptic Democracy and Vesicular Transport in Axons

    Science.gov (United States)

    Bressloff, Paul C.; Levien, Ethan

    2015-04-01

    Synaptic democracy concerns the general problem of how regions of an axon or dendrite far from the cell body (soma) of a neuron can play an effective role in neuronal function. For example, stimulated synapses far from the soma are unlikely to influence the firing of a neuron unless some sort of active dendritic processing occurs. Analogously, the motor-driven transport of newly synthesized proteins from the soma to presynaptic targets along the axon tends to favor the delivery of resources to proximal synapses. Both of these phenomena reflect fundamental limitations of transport processes based on a localized source. In this Letter, we show that a more democratic distribution of proteins along an axon can be achieved by making the transport process less efficient. This involves two components: bidirectional or "stop-and-go" motor transport (which can be modeled in terms of advection-diffusion), and reversible interactions between motor-cargo complexes and synaptic targets. Both of these features have recently been observed experimentally. Our model suggests that, just as in human societies, there needs to be a balance between "efficiency" and "equality".

  18. Primary motor and premotor cortex in implicit sequence learning--evidence for competition between implicit and explicit human motor memory systems.

    Science.gov (United States)

    Kantak, Shailesh S; Mummidisetty, Chaithanya K; Stinear, James W

    2012-09-01

    Implicit and explicit memory systems for motor skills compete with each other during and after motor practice. Primary motor cortex (M1) is known to be engaged during implicit motor learning, while dorsal premotor cortex (PMd) is critical for explicit learning. To elucidate the neural substrates underlying the interaction between implicit and explicit memory systems, adults underwent a randomized crossover experiment of anodal transcranial direct current stimulation (AtDCS) applied over M1, PMd or sham stimulation during implicit motor sequence (serial reaction time task, SRTT) practice. We hypothesized that M1-AtDCS during practice will enhance online performance and offline learning of the implicit motor sequence. In contrast, we also hypothesized that PMd-AtDCS will attenuate performance and retention of the implicit motor sequence. Implicit sequence performance was assessed at baseline, at the end of acquisition (EoA), and 24 h after practice (retention test, RET). M1-AtDCS during practice significantly improved practice performance and supported offline stabilization compared with Sham tDCS. Performance change from EoA to RET revealed that PMd-AtDCS during practice attenuated offline stabilization compared with M1-AtDCS and sham stimulation. The results support the role of M1 in implementing online performance gains and offline stabilization for implicit motor sequence learning. In contrast, enhancing the activity within explicit motor memory network nodes such as the PMd during practice may be detrimental to offline stabilization of the learned implicit motor sequence. These results support the notion of competition between implicit and explicit motor memory systems and identify underlying neural substrates that are engaged in this competition. © 2012 The Authors. European Journal of Neuroscience © 2012 Federation of European Neuroscience Societies and Blackwell Publishing Ltd.

  19. 49 CFR 396.13 - Driver inspection.

    Science.gov (United States)

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS INSPECTION, REPAIR, AND MAINTENANCE § 396.13 Driver inspection. Before driving a motor vehicle, the driver shall: (a) Be satisfied that the motor vehicle is in safe operating condition; (b) Review the last driver vehicle inspection...

  20. Intelligent transportation systems field operational test cross-cutting study : advanced traveler information systems

    Science.gov (United States)

    1998-09-01

    Approximately 2 million roadside inspections of commercial motor vehicles (CMVs) are conducted annually, primarily through the joint Federal and State Motor Carrier Safety Assistance Program (MCSAP). Vehicles and drivers with serious safety problems ...

  1. Non-contact transportation using near-field acoustic levitation

    Science.gov (United States)

    Ueha; Hashimoto; Koike

    2000-03-01

    Near-field acoustic levitation, where planar objects 10 kg in weight can levitate stably near the vibrating plate, is successfully applied both to non-contact transportation of objects and to a non-contact ultrasonic motor. Transporting apparatuses and an ultrasonic motor have been fabricated and their characteristics measured. The theory of near-field acoustic levitation both for a piston-like sound source and a flexural vibration source is also briefly described.

  2. 49 CFR 1.51 - Delegations to Federal Transit Administrator.

    Science.gov (United States)

    2010-10-01

    ... Plan No. 2 of 1968 (5 U.S.C. app. 1). (c) Section 10 of the Urban Mass Transportation Assistance Act of... 49 Transportation 1 2010-10-01 2010-10-01 false Delegations to Federal Transit Administrator. 1.51 Section 1.51 Transportation Office of the Secretary of Transportation ORGANIZATION AND DELEGATION OF...

  3. 76 FR 12211 - Commercial Space Transportation Advisory Committee-Public Teleconference

    Science.gov (United States)

    2011-03-04

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Commercial Space Transportation Advisory Committee--Public Teleconference AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Commercial Space Transportation Advisory Committee Teleconference (COMSTAC). SUMMARY: Pursuant...

  4. Keeping Order: Motor-Car Regulation and the Defeat of Victoria's 1905 Motor-Car Bill

    Directory of Open Access Journals (Sweden)

    Rick Clapton

    2004-10-01

    Full Text Available At the turn of the twentieth century some upper-class Victorians became motorists; consequently, for the first time ever, regulation and policing intersected with this class of society. By 1905 so many concerns had been raised about compromised public order and safety that the Victorian State Government attempted to implement a Motor Car Bill based on its English predecessor (1903. Wealthy motorists possessed power and influence, however, which contributed to the postponement of legislation until 1910. Additionally, parliamentarians were drawn from the same social class as motorists, and, in creating regulation, they were potentially regulating their peers, colleagues and friends. The private motor-car also brought with it new issues of civil liberty and responsibility. Finding a balance between the two continued to be a problem, as private transport gradually became affordable for middle- and working-class people, and both the number of regulations and the power of the motoring lobby increased.

  5. 76 FR 82031 - Commercial Space Transportation Advisory Committee; Public Teleconference

    Science.gov (United States)

    2011-12-29

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Commercial Space Transportation Advisory Committee; Public Teleconference AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Commercial Space Transportation Advisory Committee Risk Management Working Group Teleconference...

  6. 76 FR 4743 - Commercial Space Transportation Advisory Committee-Public Teleconference

    Science.gov (United States)

    2011-01-26

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Commercial Space Transportation Advisory Committee--Public Teleconference AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Commercial Space Transportation Advisory Committee Teleconference. SUMMARY: Pursuant to Section...

  7. 75 FR 51332 - Commercial Space Transportation Advisory Committee-Public Teleconference

    Science.gov (United States)

    2010-08-19

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Commercial Space Transportation Advisory Committee--Public Teleconference AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Commercial Space Transportation Advisory Committee Teleconference. SUMMARY: Pursuant to Section...

  8. 77 FR 48585 - Commercial Space Transportation Advisory Committee-Public Teleconference

    Science.gov (United States)

    2012-08-14

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Commercial Space Transportation Advisory Committee--Public Teleconference AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Commercial Space Transportation Advisory Committee Teleconference. SUMMARY: Pursuant to Section...

  9. 78 FR 53496 - Commercial Space Transportation Advisory Committee; Public Teleconference

    Science.gov (United States)

    2013-08-29

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Commercial Space Transportation Advisory Committee; Public Teleconference AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Commercial Space Transportation Advisory Committee Teleconference. SUMMARY: Pursuant to Section...

  10. 76 FR 15041 - Commercial Space Transportation Advisory Committee-Public Teleconference

    Science.gov (United States)

    2011-03-18

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Commercial Space Transportation Advisory Committee--Public Teleconference AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Commercial Space Transportation Advisory Committee Teleconference. SUMMARY: Pursuant to Section...

  11. 76 FR 67018 - Commercial Space Transportation Advisory Committee-Public Teleconference

    Science.gov (United States)

    2011-10-28

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Commercial Space Transportation Advisory Committee--Public Teleconference AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Commercial Space Transportation Advisory Committee Teleconference. SUMMARY: Pursuant to Section...

  12. 75 FR 38866 - Commercial Space Transportation Advisory Committee-Public Teleconference

    Science.gov (United States)

    2010-07-06

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Commercial Space Transportation Advisory Committee--Public Teleconference AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Commercial Space Transportation Advisory Committee Teleconference. SUMMARY: Pursuant to Section...

  13. 78 FR 14401 - Commercial Space Transportation Advisory Committee; Public Teleconference

    Science.gov (United States)

    2013-03-05

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Commercial Space Transportation Advisory Committee; Public Teleconference AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Commercial Space Transportation Advisory Committee Teleconference. SUMMARY: Pursuant to Section...

  14. 77 FR 35102 - Commercial Space Transportation Advisory Committee; Public Teleconference

    Science.gov (United States)

    2012-06-12

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Commercial Space Transportation Advisory Committee; Public Teleconference AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Commercial Space Transportation Advisory Committee Teleconference. SUMMARY: Pursuant to Section...

  15. 77 FR 65443 - Commercial Space Transportation Advisory Committee-Public Teleconference

    Science.gov (United States)

    2012-10-26

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Commercial Space Transportation Advisory Committee--Public Teleconference AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Commercial Space Transportation Advisory Committee Teleconference. SUMMARY: Pursuant to Section...

  16. Thermophilic P-loop transport ATPases : Enzyme function and energetics at high temperature

    NARCIS (Netherlands)

    Pretz, Monika Gyöngyi

    2007-01-01

    Primary transport ATPases are divided into several superfamilies; amongst others including ATPases of the ABC transporter superfamily, the F-ATPase superfamily or the motor ATPases of the General Secretory (Sec) pathway. Motor proteins from these superfamilies show a low sequence similarity, except

  17. FMCSA safety program effectiveness measurement : carrier intervention effectiveness model, version 1.0, summary report for fiscal years 2009, 2010, 2011.

    Science.gov (United States)

    2015-01-01

    The Federal Motor Carrier Safety Administration (FMCSA), in cooperation with the John A. Volpe National : Transportation Systems Center (Volpe), has developed a quantitative model to measure the effectiveness of motor : carrier interventions in terms...

  18. 76 FR 54932 - Revisions and Additions to Motor Vehicle Fuel Economy Label; Correction

    Science.gov (United States)

    2011-09-06

    ...-AK73 Revisions and Additions to Motor Vehicle Fuel Economy Label; Correction AGENCY: Environmental... regarding labeling of cars and trucks with fuel economy and environmental information in the Federal...

  19. Voltage directive drive with claw pole motor and control without rotor position indicator

    Science.gov (United States)

    Stroenisch, Volker Ewald

    Design and testing of a voltage directive drive for synchronous variable speed claw pole motor and control without rotor position indicator is described. Economic analysis of the designed regulation is performed. Computations of stationary and dynamic behavior are given and experimental operational behavior is determined. The motors can be used for electric transportation vehicles, diesel motors, and electric railway engines.

  20. Regional disparity of urban passenger transport associated GHG (greenhouse gas) emissions in China: A review

    International Nuclear Information System (INIS)

    Hao, Han; Geng, Yong; Wang, Hewu; Ouyang, Minggao

    2014-01-01

    With China’s urbanization and motorization, greenhouse gas (GHG) emissions from urban passenger transport increased rapidly over recent years. As we estimated, China’s urban passenger transport associated motorized travel, energy consumption and lifecycle GHG emissions reached 2815 billion passenger kilometers (pkm), 77 million tons of oil equivalent (toe) and 335 million ton CO 2 equivalent in 2010, over half of which were located in eastern provinces. Over national level, GHG emissions by private passenger vehicles, business passenger vehicles, taxis, motorcycles, E-bikes, transit buses and urban rails accounted for 57.7%, 13.0%, 7.7%, 8.6%, 1.8%, 10.5% and 0.7% of the total. Significant regional disparity was observed. The province-level per capita GHG emissions ranged from 285 kg/capita in Guizhou to 1273 kg/capita in Beijing, with national average of 486 kg/capita. Depending on province context and local policy orientation, the motorization pathways of China’s several highest motorized provinces are quite diverse. We concluded that motorization rate and transport structure were the substantial factors determining urban passenger transport associated GHG emissions. Considering the great potential of urban passenger transport growth in China, policies guiding the optimization of transport structure should be in place with priority in eastern provinces. - Highlights: • Province-leveled motorized travel, energy consumption and GHG emissions in China were studied. • Significant regional disparities on urban passenger transport were observed. • Region-specific sustainable transport energy policies were discussed

  1. 75 FR 52058 - Commercial Space Transportation Advisory Committee-Public Teleconference

    Science.gov (United States)

    2010-08-24

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Commercial Space Transportation Advisory Committee-Public Teleconference AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Commercial Space Transportation Advisory Committee Teleconference. SUMMARY: Pursuant to Section 10...

  2. PREDICTION OF AIR POLLUTION FROM MOTOR TRANSPORT ON CITY STREETS AND DISTRICTS

    Directory of Open Access Journals (Sweden)

    T. I. Rusakova

    2013-11-01

    Full Text Available Purpose. Development of applied numerical model for prediction of atmospheric pollution rate on streets and districts of a city taking into account chemical transformations of pollutants. Methodology. To solve hydrodynamic task of determining velocity field of wind flow in street the method of discrete vortices was used, in the city district – the method of separation flows vortex of ideal incompressible fluid, for solution equation of pollutant transfer - alternating triangular implicit difference scheme. Findings.An efficient numerical model using the type of «street canyons»for prediction of air quality on city streets and districts with emissions from motor transport considering chemical transformations of pollutants was designed in the work. Originality.The numerical model, which allows taking into account impact of buildings on pollutants dispersion and requiring a small consumption of computer time during practical realization was created. The advantage of the model is the possibility of rapid calculation of emissions dispersion in the street with considering the chemical reactions of pollutants. Practical value. The developed numerical model can be used in practice during the planning of new highways in new urban areas or in the renovation of old ones, for a series of calculations that require search of different variants for arrangement of buildings, highways, under certain weather conditions.

  3. 49 CFR 392.14 - Hazardous conditions; extreme caution.

    Science.gov (United States)

    2010-10-01

    ... CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS DRIVING OF COMMERCIAL MOTOR VEHICLES Driving of Commercial Motor Vehicles § 392.14 Hazardous conditions... nearest point at which the safety of passengers is assured. [33 FR 19732, Dec. 25, 1968, as amended at 60...

  4. Cooperative Threat Reduction: Solid Rocket Motor Disposition Facility Project (D-2003-131)

    National Research Council Canada - National Science Library

    2003-01-01

    .... DoD contracted with Lockheed Martin Advanced Environmental Systems for $52.4 million to design, develop, fabricate, and test a closed burn, solid rocket motor disposition facility for the Russian Federation in April 1997...

  5. Engineering controllable bidirectional molecular motors based on myosin

    Science.gov (United States)

    Chen, Lu; Nakamura, Muneaki; Schindler, Tony D.; Parker, David; Bryant, Zev

    2012-04-01

    Cytoskeletal motors drive the transport of organelles and molecular cargoes within cells and have potential applications in molecular detection and diagnostic devices. Engineering molecular motors with controllable properties will allow selective perturbation of mechanical processes in living cells and provide optimized device components for tasks such as molecular sorting and directed assembly. Biological motors have previously been modified by introducing activation/deactivation switches that respond to metal ions and other signals. Here, we show that myosin motors can be engineered to reversibly change their direction of motion in response to a calcium signal. Building on previous protein engineering studies and guided by a structural model for the redirected power stroke of myosin VI, we have constructed bidirectional myosins through the rigid recombination of structural modules. The performance of the motors was confirmed using gliding filament assays and single fluorophore tracking. Our strategy, in which external signals trigger changes in the geometry and mechanics of myosin lever arms, should make it possible to achieve spatiotemporal control over a range of motor properties including processivity, stride size and branchpoint turning.

  6. 41 CFR 109-26.501 - Purchase of new motor vehicles.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Purchase of new motor vehicles. 109-26.501 Section 109-26.501 Public Contracts and Property Management Federal Property Management Regulations System (Continued) DEPARTMENT OF ENERGY PROPERTY MANAGEMENT REGULATIONS SUPPLY AND...

  7. FMCSA Safety Program Effectiveness Measurement: Carrier Intervention Effectiveness Model (CIEM), Version 1.1 Report for Fiscal Year 2014 Interventions

    Science.gov (United States)

    2018-04-01

    The Federal Motor Carrier Safety Administration (FMCSA), in cooperation with the John A. Volpe National Transportation Systems Center (Volpe), has developed a quantitative model to measure the effectiveness of motor carrier interventions in terms of ...

  8. FMCSA safety program effectiveness measurement : Carrier Intervention Effectiveness Model (CIEM), Version 1.1, report for fiscal year 2013 interventions.

    Science.gov (United States)

    2017-04-01

    The Federal Motor Carrier Safety Administration (FMCSA), in cooperation with the John A. Volpe National Transportation Systems Center (Volpe), has developed a quantitative model to measure the effectiveness of motor carrier interventions in terms of ...

  9. Reactor coolant pump transportation incident

    International Nuclear Information System (INIS)

    Noce, D.

    1992-01-01

    This paper reports on an incident, which occurred on August 27, 1991, in which a Reactor Coolant Pump motor en route from Surry Power Station to Westinghouse repair facilities struck the overpass at the junction of Interstate 64 and Jefferson Avenue in Newport News, Virginia. The transport container that housed the reactor coolant pump motor failed to clear the overpass. The force of the impact dislodged the container and motor from the truck bed, and it landed on the acceleration land and road shoulder. Upon impact, the container broke open and exposed the reactor coolant pump motor. Incidental radioactively contaminated water that remained in the motor coolers drained onto the road, contaminating the aggregate as well as the underlying gravel

  10. An examination of the Hazardous Materials Transportation Uniform Safety Act (HMTUSA): A southern perspective

    International Nuclear Information System (INIS)

    1992-03-01

    On November 16,1990, President Bush signed into law the most comprehensive amendments to the Hazardous Materials Transportation Act (HMTA) in 15 years. The Hazardous Materials Transportation Uniform Safety Act of 1990 (HMTUSA) was created by Congress in an effort to strengthen and clarify the HMTA. This paper will discuss the act's provisions as they affect shipments of spent fuel and high-level radioactive materials as well as the impact of those provisions on routing and emergency response issues in the southern region. HMTUSA consists of seven key provisions that affect radioactive materials: clarification of regulatory jurisdiction; highway routing standards; broadened industry registration; safety permits for motor carriers of high risk materials; expanded nuclear transportation requirements; new provisions for emergency response training and planning; and a public process for assessing the feasibility of a federally operated central reporting system and data center. In addition to amending various HMTA provisions, the new HMTUSA act provides appropriations to carry out the specific goals of the legislation. The act authorizes appropriations for the 1991, 1992 and 1993 fiscal years

  11. 21 CFR 890.5150 - Powered patient transport.

    Science.gov (United States)

    2010-04-01

    ...) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Therapeutic Devices § 890.5150 Powered patient transport. (a) Identification. A powered patient transport is a motorized device intended for medical... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Powered patient transport. 890.5150 Section 890...

  12. Transportation Improvement Program of the Mid-Ohio Regional Planning Commission

    Science.gov (United States)

    1996-06-20

    The MORPC Transportation Improvement program (TIP) is a staged, multi-year schedule of regionally significant transportation improvements in the Columbus area. The Federal-aid Highway Act of 1962 and the federal Urban Mass Transportation Act of 1964 ...

  13. Bicaudal-D: Switching motors, cargo and direction

    NARCIS (Netherlands)

    G.D. Splinter (Daniël)

    2008-01-01

    textabstractScope of this thesis Transport of vesicles and organelles is an essential cellular process. Proteins like Rab GTPases, specialized adaptor proteins and motor proteins are involved in targeting and movement of cargos to their destination. This thesis describes the function of the

  14. US military expenditures to protect the use of Persian Gulf oil for motor vehicles

    Energy Technology Data Exchange (ETDEWEB)

    Delucchi, Mark A. [Institute of Transportation Studies, University of California, Davis, CA 95616 (United States); Murphy, James J. [Department of Economics, University of Alaska-Anchorage, Anchorage, AK 99501 (United States)

    2008-06-15

    Analyses of the full social cost of motor vehicle use in the US often estimate an 'oil import premium' that includes the military cost of defending oil supplies from the Persian Gulf. Estimates of this cost have ranged from essentially zero to upwards of a $1 per gallon (about $0.25 per liter). In this paper, we attempt to narrow this range, by carefully answering the question: ''If the US highway transportation sector did not use oil, how much would the US federal government reduce its military commitment in the Persian Gulf?'' We work towards our answer in five steps, accounting for interests not related to oil, the interests of other oil-consuming countries, the interests of producers apart from the interests of consumers, and the interests of non-highway users of oil. We estimate that were there no oil in the Persian Gulf, then US combined peacetime and wartime defense expenditures might be reduced in the long run by roughly $27-$73 billion per year (in 2004 dollars), of which roughly $6-$25 billion annually ($0.03-$0.15 per gallon or $0.01-$0.04 per liter) is attributable to motor-vehicle use. (author)

  15. Transportation legislative data base : state radioactive materials transportation statute compilation, 1989-1993

    Science.gov (United States)

    1994-04-30

    The Transportation Legislative Data Base (TLDB) is a computer-based information service containing summaries of federal, state and certain local government statutes and regulations relating to the transportation of radioactive materials in the United...

  16. Elevated mRNA-levels of distinct mitochondrial and plasma membrane Ca2+ transporters in individual hypoglossal motor neurons of endstage SOD1 transgenic mice.

    Directory of Open Access Journals (Sweden)

    Tobias eMühling

    2014-11-01

    Full Text Available Disturbances in Ca2+ homeostasis and mitochondrial dysfunction have emerged as major pathogenic features in familial and sporadic forms of Amyotrophic Lateral Sclerosis (ALS, a fatal degenerative motor neuron disease. However, the distinct molecular ALS-pathology remains unclear. Recently, an activity-dependent Ca2+ homeostasis deficit, selectively in highly vulnerable cholinergic motor neurons in the hypoglossal nucleus (hMNs from a common ALS mouse model, endstage superoxide dismutase SOD1G93A transgenic mice, was described. This functional deficit was defined by a reduced hMN mitochondrial Ca2+ uptake capacity and elevated Ca2+ extrusion across the plasma membrane. To address the underlying molecular mechanisms, here we quantified mRNA-levels of respective potential mitochondrial and plasma membrane Ca2+ transporters in individual, choline-acetyltransferase (ChAT positive hMNs from wildtype (WT and endstage SOD1G93A mice, by combining UV laser microdissection with RT-qPCR techniques, and specific data normalization. As ChAT cDNA levels as well as cDNA and genomic DNA levels of the mitochondrially encoded NADH dehydrogenase ND1 were not different between hMNs from WT and endstage SOD1G93A mice, these genes were used to normalize hMN-specific mRNA-levels of plasma membrane and mitochondrial Ca2+ transporters, respectively. We detected about 2-fold higher levels of the mitochondrial Ca2+ transporters MCU/MICU1, Letm1 and UCP2 in remaining hMNs from endstage SOD1G93A mice. These higher expression-levels of mitochondrial Ca2+ transporters in individual hMNs were not associated with a respective increase in number of mitochondrial genomes, as evident from hMN specific ND1 DNA quantification. Normalized mRNA-levels for the plasma membrane Na2+/Ca2+exchanger NCX1 was also about 2-fold higher in hMNs from SOD1G93A mice. Thus, pharmacological stimulation of Ca2+ transporters in highly vulnerable hMNs might offer a novel neuroprotective strategy for ALS.

  17. Motorized transport in the city area of Besancon and its impact on energy consumption; Les deplacements motorises dans l`agglomeration bisontine et leurs consequences energetiques

    Energy Technology Data Exchange (ETDEWEB)

    Abram, G.

    1995-12-31

    Energy consumption, pollutant emissions and environmental burdens due to motor traffic in the city area of Besancon has been determined by statistics, counting and sample surveys. A computer model has been developed to simulate the impact of different elements and policy measures as the development of public transport systems, traffic regulation, limiting the accessibility of certain areas and car pooling. (C.B.) 101 refs.

  18. Motorized transport in the city area of Besancon and its impact on energy consumption; Les deplacements motorises dans l`agglomeration bisontine et leurs consequences energetiques

    Energy Technology Data Exchange (ETDEWEB)

    Abram, G

    1996-12-31

    Energy consumption, pollutant emissions and environmental burdens due to motor traffic in the city area of Besancon has been determined by statistics, counting and sample surveys. A computer model has been developed to simulate the impact of different elements and policy measures as the development of public transport systems, traffic regulation, limiting the accessibility of certain areas and car pooling. (C.B.) 101 refs.

  19. 48 CFR 47.105 - Transportation assistance.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Transportation assistance... MANAGEMENT TRANSPORTATION General 47.105 Transportation assistance. (a) Civilian Government activities that do not have transportation officers, or otherwise need assistance on transportation matters, shall...

  20. 49 CFR 396.7 - Unsafe operations forbidden.

    Science.gov (United States)

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS INSPECTION, REPAIR, AND MAINTENANCE § 396.7 Unsafe operations forbidden. (a) General. A motor vehicle shall not be operated in such a condition as to likely cause an accident or a breakdown of the vehicle. (b) Exemption. Any motor vehicle...

  1. Electric drive motors for industrial robots

    Science.gov (United States)

    Fichtner, K.

    1985-04-01

    In robotized industrial plants it is possible to use electric motors in the technological process and also for control, assembly, transport, testing, and measurements. Particularly suitable for these applications are permanent-magnet d.c. motors. A new special series was developed for industrial robots with hinge joints in kinematic pairs. The complete drive includes thyristors or transistor controls with regulators and, if necessary, a line transformer as well as a servomotor with tachometer and odometer for speed, current, and position control. The drive is coupled to a robot tong through mechanical torque and force converters. In addition to a 0 to 4000 rpm speed regulation, without wobble at low speeds, and a high torque-to-weight ratio for repetitive short-time heavy duty, these low-inertia motors develop high starting and accelerating torques over the entire speed range. They operate from a 1 to O 220 V a.c. line through a rectifier. The motors are totally enclosed, or of open construction for better ventilation. Their windings have class F insulation for operation at ambient temperatures up to 40 C.

  2. Federal databases

    International Nuclear Information System (INIS)

    Welch, M.J.; Welles, B.W.

    1988-01-01

    Accident statistics on all modes of transportation are available as risk assessment analytical tools through several federal agencies. This paper reports on the examination of the accident databases by personal contact with the federal staff responsible for administration of the database programs. This activity, sponsored by the Department of Energy through Sandia National Laboratories, is an overview of the national accident data on highway, rail, air, and marine shipping. For each mode, the definition or reporting requirements of an accident are determined and the method of entering the accident data into the database is established. Availability of the database to others, ease of access, costs, and who to contact were prime questions to each of the database program managers. Additionally, how the agency uses the accident data was of major interest

  3. 76 FR 7560 - Agency Information Collection Activities; Proposed Collection; Comment Request; Transportation...

    Science.gov (United States)

    2011-02-10

    ... Activities; Proposed Collection; Comment Request; Transportation Conformity Determinations for Federally... federally supported transportation activities are consistent with (``conform to'') the purpose of the state air quality implementation plan (SIP). Transportation activities include transportation plans...

  4. 49 CFR 541.2 - Purpose.

    Science.gov (United States)

    2010-10-01

    ... OF TRANSPORTATION FEDERAL MOTOR VEHICLE THEFT PREVENTION STANDARD § 541.2 Purpose. The purpose of this standard is to reduce the incidence of motor vehicle thefts by facilitating the tracing and recovery of parts from stolen vehicles. ...

  5. Integration of Flex Nozzle System and Electro Hydraulic Actuators to Solid Rocket Motors

    Science.gov (United States)

    Nayani, Kishore Nath; Bajaj, Dinesh Kumar

    2017-10-01

    A rocket motor assembly comprised of solid rocket motor and flex nozzle system. Integration of flex nozzle system and hydraulic actuators to the solid rocket motors are done after transportation to the required place where integration occurred. The flex nozzle system is integrated to the rocket motor in horizontal condition and the electro hydraulic actuators are assembled to the flex nozzle systems. The electro hydraulic actuators are connected to the hydraulic power pack to operate the actuators. The nozzle-motor critical interface are insulation diametrical compression, inhibition resin-28, insulation facial compression, shaft seal `O' ring compression and face seal `O' ring compression.

  6. 49 CFR 385.14 - Motor carriers, brokers, and freight forwarders delinquent in paying civil penalties: prohibition...

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Motor carriers, brokers, and freight forwarders....14 Motor carriers, brokers, and freight forwarders delinquent in paying civil penalties: prohibition... commerce under 49 CFR 386.83. (b) A broker, freight forwarder, or for-hire motor carrier that has failed to...

  7. Transportation training: Focusing on movement of hazardous substances and wastes

    International Nuclear Information System (INIS)

    Jones, E.; Moreland, W.M.

    1988-01-01

    Over the past 25 years extensive federal legislation involving the handling and transport of hazardous materials/waste has been passed that has resulted in numerous overlapping regulations administered and enforced by different federal agencies. The handling and transport of hazardous materials/waste involves a significant number of workers who are subject to a varying degree of risk should an accident occur during handling or transport. Effective transportation training can help workers address these risks and mitigate them, and at the same time enable ORNL to comply with the federal regulations concerning the transport of hazardous materials/waste. This presentation will outline how the Environmental and Health Protection Division's Technical Resources and Training Program at the Oak Ridge National Laboratory, working with transportation and waste disposal personnel, are developing and implementing a comprehensive transportation safety training program to meet the needs of our workers while satisfying appropriate federal regulations. 8 refs., 5 figs., 3 tabs

  8. 78 FR 41852 - Hours of Service for Commercial Motor Vehicle Drivers; Regulatory Guidance Concerning Off-Duty Time

    Science.gov (United States)

    2013-07-12

    ... provided: 1. The driver is relieved of all duty and responsibility for the care and custody of the vehicle... Service for Commercial Motor Vehicle Drivers; Regulatory Guidance Concerning Off-Duty Time AGENCY: Federal... motor vehicle (CMV) driver to record meal and other routine stops made during a work shift as off-duty...

  9. SmartPark Technology Demonstration Project, Phase II: Final Report : Technology Brief

    Science.gov (United States)

    2018-05-01

    In 2000, the National Transportation Safety Board recommended that the Federal Motor Carrier Safety Administration (FMCSA) create a guide to inform truck drivers about locations and availability of parking. In 2002, the Federal Highway Administration...

  10. 41 CFR 102-118.10 - What is a transportation audit?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What is a transportation audit? 102-118.10 Section 102-118.10 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION TRANSPORTATION 118-TRANSPORTATION...

  11. 41 CFR 102-118.15 - What is a transportation payment?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What is a transportation payment? 102-118.15 Section 102-118.15 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION TRANSPORTATION 118-TRANSPORTATION...

  12. 49 CFR 22.15 - Delinquency on Federal, State, or Municipality Debt.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Delinquency on Federal, State, or Municipality... PROGRAM (STLP) Policies Applying to STLP Loans § 22.15 Delinquency on Federal, State, or Municipality Debt... appropriate Federal and State databases. (b) If any delinquencies are determined during the application...

  13. Behavioral Phenotyping of Dopamine Transporter Knockout Rats: Compulsive Traits, Motor Stereotypies, and Anhedonia

    Directory of Open Access Journals (Sweden)

    Stefano Cinque

    2018-02-01

    Full Text Available Alterations in dopamine neurotransmission are generally associated with diseases such as attention-deficit/hyperactivity disorder (ADHD and obsessive-compulsive disorder (OCD. Such diseases typically feature poor decision making and lack of control on executive functions and have been studied through the years using many animal models. Dopamine transporter (DAT knockout (KO and heterozygous (HET mice, in particular, have been widely used to study ADHD. Recently, a strain of DAT KO rats has been developed (1. Here, we provide a phenotypic characterization of reward sensitivity and compulsive choice by adult rats born from DAT–HET dams bred with DAT–HET males, in order to further validate DAT KO rats as an animal model for preclinical research. We first tested DAT KO rats’ sensitivity to rewarding stimuli, provided by highly appetitive food or sweet water; then, we tested their choice behavior with an Intolerance-to-Delay Task (IDT. During these tests, DAT KO rats appeared less sensitive to rewarding stimuli than wild-type (WT and HET rats: they also showed a prominent hyperactive behavior with a rigid choice pattern and a wide number of compulsive stereotypies. Moreover, during the IDT, we tested the effects of amphetamine (AMPH and RO-5203648, a trace amine-associated receptor 1 (TAAR1 partial agonist. AMPH accentuated impulsive behaviors in WT and HET rats, while it had no effect in DAT KO rats. Finally, we measured the levels of tyrosine hydroxylase, dopamine receptor 2 (D2, serotonin transporter, and TAAR1 mRNA transcripts in samples of ventral striatum, finding no significant differences between WT and KO genotypes. Throughout this study, DAT KO rats showed alterations in decision-making processes and in motivational states, as well as prominent motor and oral stereotypies: more studies are warranted to fully characterize and efficiently use them in preclinical research.

  14. 78 FR 27284 - Public Transportation on Indian Reservations Program; Tribal Transit Program

    Science.gov (United States)

    2013-05-09

    ... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Public Transportation on Indian... Federal Register Notice (77 FR 67439) Fiscal Year 2013 Public Transportation on Indian Reservation Program... formula apportionment to eligible Indian tribes providing public transportation on tribal lands. FTA...

  15. 49 CFR 555.7 - Processing of applications.

    Science.gov (United States)

    2010-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TEMPORARY EXEMPTION FROM MOTOR VEHICLE SAFETY AND BUMPER STANDARDS General § 555.7 Processing of applications. (a) The NHTSA publishes in the Federal Register, affording...

  16. 41 CFR 109-40.103-1 - Domestic transportation.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Domestic transportation... Regulations System (Continued) DEPARTMENT OF ENERGY PROPERTY MANAGEMENT REGULATIONS AVIATION, TRANSPORTATION, AND MOTOR VEHICLES 40-TRANSPORTATION AND TRAFFIC MANAGEMENT 40.1-General Provision § 109-40.103-1...

  17. Engineering controllable bidirectional molecular motors based on myosin

    Science.gov (United States)

    Chen, Lu; Nakamura, Muneaki; Schindler, Tony D.; Parker, David; Bryant, Zev

    2012-01-01

    Cytoskeletal motors drive the transport of organelles and molecular cargoes within cells1, and have potential applications in molecular detection and diagnostic devices2,3. Engineering molecular motors with dynamically controllable properties will allow selective perturbation of mechanical processes in living cells, and yield optimized device components for complex tasks such as molecular sorting and directed assembly3. Biological motors have previously been modified by introducing activation/deactivation switches that respond to metal ions4,5 and other signals6. Here we show that myosin motors can be engineered to reversibly change their direction of motion in response to a calcium signal. Building on previous protein engineering studies7–11 and guided by a structural model12 for the redirected power stroke of myosin VI, we constructed bidirectional myosins through the rigid recombination of structural modules. The performance of the motors was confirmed using gliding filament assays and single fluorophore tracking. Our general strategy, in which external signals trigger changes in the geometry and mechanics of myosin lever arms, should enable spatiotemporal control over a range of motor properties including processivity, stride size13, and branchpoint turning14. PMID:22343382

  18. The commercial vehicle information systems and networks program, 2014.

    Science.gov (United States)

    2015-05-01

    The Federal Motor Carrier Safety Administration (FMCSA) was created as an operating administration within the U.S. Department of Transportation (USDOT) by the Motor Carrier Safety Improvement Act of 1999. The primary mission of the FMCSA is to reduce...

  19. APC binds the Miro/Milton motor complex to stimulate transport of mitochondria to the plasma membrane.

    Science.gov (United States)

    Mills, Kate M; Brocardo, Mariana G; Henderson, Beric R

    2016-02-01

    Mutations in adenomatous polyposis coli (APC) disrupt regulation of Wnt signaling, mitosis, and the cytoskeleton. We describe a new role for APC in the transport of mitochondria. Silencing of wild-type APC by small interfering RNA caused mitochondria to redistribute from the cell periphery to the perinuclear region. We identified novel APC interactions with the mitochondrial kinesin-motor complex Miro/Milton that were mediated by the APC C-terminus. Truncating mutations in APC abolished its ability to bind Miro/Milton and reduced formation of the Miro/Milton complex, correlating with disrupted mitochondrial distribution in colorectal cancer cells that could be recovered by reconstitution of wild-type APC. Using proximity ligation assays, we identified endogenous APC-Miro/Milton complexes at mitochondria, and live-cell imaging showed that loss of APC slowed the frequency of anterograde mitochondrial transport to the membrane. We propose that APC helps drive mitochondria to the membrane to supply energy for cellular processes such as directed cell migration, a process disrupted by cancer mutations. © 2016 Mills et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  20. Abnormal mitochondrial transport and morphology as early pathological changes in human models of spinal muscular atrophy

    Directory of Open Access Journals (Sweden)

    Chong-Chong Xu

    2016-01-01

    Full Text Available Spinal muscular atrophy (SMA, characterized by specific degeneration of spinal motor neurons, is caused by mutations in the survival of motor neuron 1, telomeric (SMN1 gene and subsequent decreased levels of functional SMN. How the deficiency of SMN, a ubiquitously expressed protein, leads to spinal motor neuron-specific degeneration in individuals affected by SMA remains unknown. In this study, we examined the role of SMN in mitochondrial axonal transport and morphology in human motor neurons by generating SMA type 1 patient-specific induced pluripotent stem cells (iPSCs and differentiating these cells into spinal motor neurons. The initial specification of spinal motor neurons was not affected, but these SMA spinal motor neurons specifically degenerated following long-term culture. Moreover, at an early stage in SMA spinal motor neurons, but not in SMA forebrain neurons, the number of mitochondria, mitochondrial area and mitochondrial transport were significantly reduced in axons. Knocking down of SMN expression led to similar mitochondrial defects in spinal motor neurons derived from human embryonic stem cells, confirming that SMN deficiency results in impaired mitochondrial dynamics. Finally, the application of N-acetylcysteine (NAC mitigated the impairment in mitochondrial transport and morphology and rescued motor neuron degeneration in SMA long-term cultures. Furthermore, NAC ameliorated the reduction in mitochondrial membrane potential in SMA spinal motor neurons, suggesting that NAC might rescue apoptosis and motor neuron degeneration by improving mitochondrial health. Overall, our data demonstrate that SMN deficiency results in abnormal mitochondrial transport and morphology and a subsequent reduction in mitochondrial health, which are implicated in the specific degeneration of spinal motor neurons in SMA.

  1. 77 FR 71717 - Federal Motor Vehicle Safety Standards; Lamps, Reflective Devices, and Associated Equipment

    Science.gov (United States)

    2012-12-04

    ... compliance strategies, potentially imposing costs on manufacturers while not improving safety. V. Regulatory... tort cause of action is impliedly preempted. See Geier v. American Honda Motor Co., 529 U.S. 861 (2000...

  2. 49 CFR 665.25 - Transportation of vehicle.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Transportation of vehicle. 665.25 Section 665.25 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BUS TESTING Operations § 665.25 Transportation of vehicle. A manufacturer shall...

  3. OPAL extension for permanent-magnet motors; OPAL-Erweiterung fuer Permanentmagnet-Motoren - Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Tanner, R

    2008-07-01

    This final report for the Swiss Federal Office of Energy (SFOE) takes a look at an extension to the OPAL software that is concerned with the energy-efficient design of pump and fan systems that use induction motors. This software has been extended by a module for permanent magnet motors which directly addresses the question of how much energy and cost can be saved through the use of this type of motors compared to ASM standard motors. However, it is noted that certain parameters of permanent magnet motors necessary to make use of this new design feature must be available, which is currently not the case. In order to make this design application available to a wider group of users, a web-based user interface has been developed. New Web-2.0 features that have been included to provide improved usability are discussed. In addition, it is noted that the software has now been adapted to support German, English and French versions. Also, the EuroDEEM database has been integrated, thus giving access to the performance data of more than 10,000 motors.

  4. 23 CFR 140.912 - Transportation.

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Transportation. 140.912 Section 140.912 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Railroad Work § 140.912 Transportation. (a) Employees. The company's cost of necessary employee...

  5. Making choices about hydrogen: Transport issues for developing ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    12.6 Malaysian government hydrogen fuel-cell research, development and ...... Policies, promises and practices: The application of hydrogen fuel cells in the transport ... This contrasts with the internal combustion engine, whose principles were ..... through annual registration fees and taxes on motor vehicles and motor fuel.

  6. Transports and environment; Transports et environnements

    Energy Technology Data Exchange (ETDEWEB)

    Anon,

    2004-07-01

    In the framework of the greenhouse gases reduction, this study proposes many advices to control the fuel consumption of the vehicles and to change habits in the transportation sector. It presents also the alternatives to the pollutant today vehicles in the domain of the vehicles and buses fuels but also the new motors. Many Internet addresses are provided to complete the presentation. (A.L.B.)

  7. 14 CFR Special Federal Aviation... - Air Traffic Control System Emergency Operation

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Air Traffic Control System Emergency Operation Federal Special Federal Aviation Regulation No. 60 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES GENERAL OPERATING AND FLIGHT RULES Pt. 91, SFAR No. 60...

  8. Mechanistic logic underlying the axonal transport of cytosolic proteins

    Science.gov (United States)

    Scott, David A.; Das, Utpal; Tang, Yong; Roy, Subhojit

    2011-01-01

    Proteins vital to presynaptic function are synthesized in the neuronal perikarya and delivered into synapses via two modes of axonal transport. While membrane-anchoring proteins are conveyed in fast axonal transport via motor-driven vesicles, cytosolic proteins travel in slow axonal transport; via mechanisms that are poorly understood. We found that in cultured axons, populations of cytosolic proteins tagged to photoactivable-GFP (PA-GFP) move with a slow motor-dependent anterograde bias; distinct from vesicular-trafficking or diffusion of untagged PA-GFP. The overall bias is likely generated by an intricate particle-kinetics involving transient assembly and short-range vectorial spurts. In-vivo biochemical studies reveal that cytosolic proteins are organized into higher-order structures within axon-enriched fractions that are largely segregated from vesicles. Data-driven biophysical modeling best predicts a scenario where soluble molecules dynamically assemble into mobile supra-molecular structures. We propose a model where cytosolic proteins are transported by dynamically assembling into multi-protein complexes that are directly/indirectly conveyed by motors. PMID:21555071

  9. 49 CFR 372.243 - Controlling distances and population data.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Controlling distances and population data. 372.243 Section 372.243 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR... EXEMPTIONS, COMMERCIAL ZONES, AND TERMINAL AREAS Commercial Zones § 372.243 Controlling distances and...

  10. 49 CFR 393.30 - Battery installation.

    Science.gov (United States)

    2010-10-01

    ... NECESSARY FOR SAFE OPERATION Lamps, Reflective Devices, and Electrical Wiring § 393.30 Battery installation... 49 Transportation 5 2010-10-01 2010-10-01 false Battery installation. 393.30 Section 393.30 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY...

  11. 49 CFR 393.28 - Wiring systems.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Wiring systems. 393.28 Section 393.28 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY... NECESSARY FOR SAFE OPERATION Lamps, Reflective Devices, and Electrical Wiring § 393.28 Wiring systems...

  12. 49 CFR 192.65 - Transportation of pipe.

    Science.gov (United States)

    2010-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Materials § 192.65 Transportation of pipe. (a) Railroad...

  13. The pattern and extent of retrograde transsynaptic transport of WGA-Alexa 488 in the phrenic motor system is dependent upon the site of application.

    Science.gov (United States)

    Goshgarian, Harry G; Buttry, Janelle L

    2014-01-30

    The first aim of the study was to determine if WGA-Alexa 488 would undergo retrograde transsynaptic transport in the phrenic motor system as we have shown with WGA-HRP in a previous study. The advantage of using WGA-Alexa 488 is that labeled neurons could be isolated and analyzed for intracellular molecular mechanisms without exposing tissue sections to chemicals for histochemical staining. The second aim of the study was to investigate the pattern and extent of labeling that occurs when WGA-Alexa 488 is applied to the cervical phrenic nerve as compared to intradiaphragmatic injection. After injecting the hemidiaphragm ipsilateral to a C2 spinal cord hemisection, WGA-Alexa 488 presumably diffused to the contralateral hemidiaphragm and labeled the phrenic nuclei bilaterally. In all animals with hemidiaphragmatic injection, the rostral ventral respiratory group (rVRG) was also labeled bilaterally in the medulla. Thus, injection of WGA-Alexa 488 into the diaphragm results in retrograde transsynaptic transport in the phrenic motor system. After applying WGA-Alexa 488 to the ipsilateral intact cervical phrenic nerve in both C2 hemisected rats and rats with a sham hemisection, only ipsilateral phrenic neurons were labeled; there was no labeling of the rVRG or any other center in the medulla. These results suggest that WGA-Alexa 488 must be applied in the vicinity of the phrenic myoneural junction where there is a high concentration of WGA receptors in order for transsynaptic transport to occur. The present study provides investigators with a new tool to study plasticity in the respiratory system after spinal cord injury. Copyright © 2013. Published by Elsevier B.V.

  14. 18 CFR 367.3920 - Account 392, Transportation equipment.

    Science.gov (United States)

    2010-04-01

    ...) Electrical vehicles. (5) Motor trucks. (6) Motorcycles. (7) Repair cars or trucks. (8) Tractors and trailers. (9) Other transportation vehicles. .... (a) This account must include the cost of transportation vehicles used for service company purposes...

  15. Permissible state permit/fee systems for radioactive materials transportation

    International Nuclear Information System (INIS)

    Friel, L.

    1987-01-01

    Many state permit/fee systems for radioactive materials transportation have been ruled inconsistent with federal law invalidated by the courts. As the date for repository operation, and its associated transportation, draws near, more states can be expected to adopt permit/fee systems. Examination of the U.S. Department of Transportation's advisory rulings and federal court cases on previous permit/fee systems gives general guidance on the type of permit/fee systems most likely to withstand challenges. Such a system would: have a simplified permit application with minimal information requirements; address a federally-defined class of hazardous or radioactive materials; allow access to all shipments conducted in compliance with federal law; charge a fee reasonably related to the costs imposed on the state by the transportation; and minimize the potential for re-directing shipments to other jurisdictions

  16. Transportation operations functions of the federal waste management system

    International Nuclear Information System (INIS)

    Shappert, L.B.; Klimas, M.J.

    1989-01-01

    This paper documents the functions that are necessary to operate the OCRWM transportation system. OCRWM's mission is to accept and transport spent fuel and high-level waste from waste generators to FWMS facilities. The emphasis is on transportation operations and assumes that all necessary facilities are in place and equipment designs and specifications are available to permit the system to operate properly. The information reported in this paper was developed for TOPO and is compatible with the draft revision of the Waste Management System Requirements and Description (SRD). 5 refs

  17. Immobilization of Caenorhabditis elegans to Analyze Intracellular Transport in Neurons.

    Science.gov (United States)

    Niwa, Shinsuke

    2017-10-18

    Axonal transport and intraflagellar transport (IFT) are essential for axon and cilia morphogenesis and function. Kinesin superfamily proteins and dynein are molecular motors that regulate anterograde and retrograde transport, respectively. These motors use microtubule networks as rails. Caenorhabditis elegans (C. elegans) is a powerful model organism to study axonal transport and IFT in vivo. Here, I describe a protocol to observe axonal transport and IFT in living C. elegans. Transported cargo can be visualized by tagging cargo proteins using fluorescent proteins such as green fluorescent protein (GFP). C. elegans is transparent and GFP-tagged cargo proteins can be expressed in specific cells under cell-specific promoters. Living worms can be fixed by microbeads on 10% agarose gel without killing or anesthetizing the worms. Under these conditions, cargo movement can be directly observed in the axons and cilia of living C. elegans without dissection. This method can be applied to the observation of any cargo molecule in any cells by modifying the target proteins and/or the cells they are expressed in. Most basic proteins such as molecular motors and adaptor proteins that are involved in axonal transport and IFT are conserved in C. elegans. Compared to other model organisms, mutants can be obtained and maintained more easily in C. elegans. Combining this method with various C. elegans mutants can clarify the molecular mechanisms of axonal transport and IFT.

  18. 48 CFR 47.102 - Transportation insurance.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Transportation insurance... MANAGEMENT TRANSPORTATION General 47.102 Transportation insurance. (a) The Government generally (1) retains... assumed responsibility. The cost of this insurance to the carrier shall be part of the transportation cost...

  19. 75 FR 50958 - Federal Motor Vehicle Safety Standards; Motorcoach Definition; Occupant Crash Protection

    Science.gov (United States)

    2010-08-18

    ... operated over 33,000 motorcoaches, they logged nearly 750 million passenger trips, and they traveled over 1..., and Puerto Rico. To be included in FARS, a crash must involve a motor vehicle traveling on a traffic...-occupant within 30 days of the crash. Motorcoaches are identified in FARS as ``cross-country intercity...

  20. Significant Guidance Issued by the Federal Motor Carrier Safety Administration

    Data.gov (United States)

    Department of Transportation — A list of Significant Guidance documents, which include guidance document disseminated to regulated entities or the general public that may reasonably be anticipated...

  1. Sustainability Aspects of Energy Conversion in Modern High-Speed Trains with Traction Induction Motors

    Directory of Open Access Journals (Sweden)

    Marc A. Rosen

    2015-03-01

    Full Text Available Some aspects are illustrated of energy conversion processes during the operation of electric railway vehicles with traction induction motors, in order to support transport systems’ sustainability. Increasing efforts are being expended to enhance the sustainability of transportation technologies and systems. Since electric drive systems are used with variable voltage variable frequency (VVVF inverters and traction induction motors, these machines with appropriate controls can realize both traction and electric braking regimes for electric traction vehicles. In line with this idea, this paper addresses the operation sustainability of electric railway vehicles highlighting the chain of interactions among the main electric equipment on an electrically driven railway system supplied from an a.c. contact line: The contact line-side converter, the machine-side converter and the traction induction motor. The paper supports the findings that electric traction drive systems using induction motors fed by network-side converters and VVVF inverters enhance the sustainable operation of railway trains.

  2. 49 CFR 374.313 - Equipment.

    Science.gov (United States)

    2010-10-01

    .... Each bus (except in commuter service) seating more than 14 passengers (not including the driver) shall..., DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS PASSENGER CARRIER REGULATIONS Adequacy of Intercity Motor Common Carrier Passenger Service § 374.313 Equipment. (a) Temperature control. A...

  3. Transportation Energy Futures: Freight Transportation Modal Shares: Scenarios for a Low-Carbon Future

    Energy Technology Data Exchange (ETDEWEB)

    Brogan, J. J. [Cambridge Systematics Inc., Cambridge, MA (United States); Aeppli, A. E. [Cambridge Systematics Inc., Cambridge, MA (United States); Brown, D. F. [Cambridge Systematics Inc., Cambridge, MA (United States); Fischer, M. J. [Cambridge Systematics Inc., Cambridge, MA (United States); Grenzeback, L. R. [Cambridge Systematics Inc., Cambridge, MA (United States); McKenzie, E. [Cambridge Systematics Inc., Cambridge, MA (United States); Vimmerstedt, L. [Cambridge Systematics Inc., Cambridge, MA (United States); Vyas, A. D. [Cambridge Systematics Inc., Cambridge, MA (United States); Witzke, E. [Cambridge Systematics Inc., Cambridge, MA (United States)

    2013-03-01

    Freight transportation modes—truck, rail, water, air, and pipeline—each serve a distinct share of the freight transportation market. A variety of factors influence the modes chosen by shippers, carriers, and others involved in freight supply chains. Analytical methods can be used to project future modal shares, and federal policy actions could influence future freight mode choices. This report considers how these topics have been addressed in existing literature and offers insights on federal policy decisions with the potential to prompt mode choices that reduce energy use and greenhouse gas emissions.

  4. 49 CFR 325.9 - Measurement tolerances.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Measurement tolerances. 325.9 Section 325.9 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY... allowed to take into account the effects of the following factors: (1) The consensus standard practice of...

  5. 78 FR 26112 - Limitation on Claims Against Proposed Public Transportation Projects; Correction

    Science.gov (United States)

    2013-05-03

    ... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Limitation on Claims Against Proposed Public Transportation Projects; Correction AGENCY: Federal Transit Administration (FTA), DOT. ACTION... Register on April 22, 2013, concerning a limitation on claims for certain specified public transportation...

  6. 42 CFR 9.11 - Animal transport.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Animal transport. 9.11 Section 9.11 Public Health... CHIMPANZEES HELD IN THE FEDERALLY SUPPORTED SANCTUARY SYSTEM § 9.11 Animal transport. The transportation of... and Regulations and the International Air Transport Association (IATA) Live Animal Regulations and...

  7. Predictors of employment for young adults with developmental motor disabilities.

    Science.gov (United States)

    Magill-Evans, Joyce; Galambos, Nancy; Darrah, Johanna; Nickerson, Christy

    2008-01-01

    To identify the personal, family, and community factors that facilitate or hinder employment for young adults with developmental motor disabilities. Quantitative methods with an embedded qualitative component were used. Seventy-six persons between the ages of 20 and 30 years of age (Mean = 25, SD = 3.1) with a diagnosis of either cerebral palsy or spina bifida completed questionnaires addressing factors such as depression, and participated in a semi-structured interview that allowed participants to describe their experiences with education, employment, transportation, and other services. Almost half of the participants (n = 35) were not currently employed. Hierarchical regression analyses indicated that gender (females were less likely to be employed), IQ (lower IQ associated with unemployment), and transportation dependence accounted for 42% of the variance in employment. Themes emerging from content analysis of the interviews supported the findings related to transportation barriers. Social reactions to disability limited employment opportunities, and participants often felt stuck in terms of employment options with limited opportunities for advancement. Transportation is a significant barrier to employment and innovative solutions are needed. Issues related to gender need to be considered when addressing employment inequities for persons with primarily motor disabilities.

  8. U.S. international trade in transportation-related goods

    Science.gov (United States)

    2003-06-01

    Trade in motor vehicles and parts makes up three : of every four dollars that the U.S. trades in : transportation-related goods. : Canada is the United States' leading trade partner : in transportation-related goods, followed by : Japan and Mexic...

  9. NASA Glenn Research Center Program in High Power Density Motors for Aeropropulsion

    Science.gov (United States)

    Brown, Gerald V.; Kascak, Albert F.; Ebihara, Ben; Johnson, Dexter; Choi, Benjamin; Siebert, Mark; Buccieri, Carl

    2005-01-01

    Electric drive of transport-sized aircraft propulsors, with electric power generated by fuel cells or turbo-generators, will require electric motors with much higher power density than conventional room-temperature machines. Cryogenic cooling of the motor windings by the liquid hydrogen fuel offers a possible solution, enabling motors with higher power density than turbine engines. Some context on weights of various systems, which is required to assess the problem, is presented. This context includes a survey of turbine engine weights over a considerable size range, a correlation of gear box weights and some examples of conventional and advanced electric motor weights. The NASA Glenn Research Center program for high power density motors is outlined and some technical results to date are presented. These results include current densities of 5,000 A per square centimeter current density achieved in cryogenic coils, finite element predictions compared to measurements of torque production in a switched reluctance motor, and initial tests of a cryogenic switched reluctance motor.

  10. Split-phase motor running as capacitor starts motor and as capacitor run motor

    Directory of Open Access Journals (Sweden)

    Yahaya Asizehi ENESI

    2016-07-01

    Full Text Available In this paper, the input parameters of a single phase split-phase induction motor is taken to investigate and to study the output performance characteristics of capacitor start and capacitor run induction motor. The value of these input parameters are used in the design characteristics of capacitor run and capacitor start motor with each motor connected to rated or standard capacitor in series with auxiliary winding or starting winding respectively for the normal operational condition. The magnitude of capacitor that will develop maximum torque in capacitor start motor and capacitor run motor are investigated and determined by simulation. Each of these capacitors is connected to the auxiliary winding of split-phase motor thereby transforming it into capacitor start or capacitor run motor. The starting current and starting torque of the split-phase motor (SPM, capacitor run motor (CRM and capacitor star motor (CSM are compared for their suitability in their operational performance and applications.

  11. Variation in motor output and motor performance in a centrally generated motor pattern

    Science.gov (United States)

    Norris, Brian J.; Doloc-Mihu, Anca; Calabrese, Ronald L.

    2014-01-01

    Central pattern generators (CPGs) produce motor patterns that ultimately drive motor outputs. We studied how functional motor performance is achieved, specifically, whether the variation seen in motor patterns is reflected in motor performance and whether fictive motor patterns differ from those in vivo. We used the leech heartbeat system in which a bilaterally symmetrical CPG coordinates segmental heart motor neurons and two segmented heart tubes into two mutually exclusive coordination modes: rear-to-front peristaltic on one side and nearly synchronous on the other, with regular side-to-side switches. We assessed individual variability of the motor pattern and the beat pattern in vivo. To quantify the beat pattern we imaged intact adults. To quantify the phase relations between motor neurons and heart constrictions we recorded extracellularly from two heart motor neurons and movement from the corresponding heart segments in minimally dissected leeches. Variation in the motor pattern was reflected in motor performance only in the peristaltic mode, where larger intersegmental phase differences in the motor neurons resulted in larger phase differences between heart constrictions. Fictive motor patterns differed from those in vivo only in the synchronous mode, where intersegmental phase differences in vivo had a larger front-to-rear bias and were more constrained. Additionally, load-influenced constriction timing might explain the amplification of the phase differences between heart segments in the peristaltic mode and the higher variability in motor output due to body shape assumed in this soft-bodied animal. The motor pattern determines the beat pattern, peristaltic or synchronous, but heart mechanics influence the phase relations achieved. PMID:24717348

  12. Development of Maglev and linear drive technology for transportation in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Masada, Eisuke [Tokyo Univ. (Germany)

    1996-12-31

    In order to realise guided ground transportation systems with superspeed, better riding comforts and environmental effects two types of maglev transports, JR-Maglev and HSST have been developed since 20 years in Japan. JR-Maglev is bases on a electro-dynamic suspension system and driven by long-stator linear synchronous motors. HSST is an electromagnetic suspension system with short-stator linear induction motor. Both systems are presented. (HW)

  13. 19 CFR 12.73 - Motor vehicle and engine compliance with Federal antipollution emission requirements.

    Science.gov (United States)

    2010-04-01

    ... requirements. This section is ancillary to the regulations of the U.S. Environmental Protection Agency (EPA.... Those regulations should be consulted for more detailed information concerning EPA emission requirements... and exclusions from emission requirements based on age of vehicle. The following motor vehicles...

  14. Assessment of the upper motor neuron in amyotrophic lateral sclerosis.

    Science.gov (United States)

    Huynh, William; Simon, Neil G; Grosskreutz, Julian; Turner, Martin R; Vucic, Steve; Kiernan, Matthew C

    2016-07-01

    Clinical signs of upper motor neuron (UMN) involvement are an important component in supporting the diagnosis of amyotrophic lateral sclerosis (ALS), but are often not easily appreciated in a limb that is concurrently affected by muscle wasting and lower motor neuron degeneration, particularly in the early symptomatic stages of ALS. Whilst recent criteria have been proposed to facilitate improved detection of lower motor neuron impairment through electrophysiological features that have improved diagnostic sensitivity, assessment of upper motor neuron involvement remains essentially clinical. As a result, there is often a significant diagnostic delay that in turn may impact institution of disease-modifying therapy and access to other optimal patient management. Biomarkers of pathological UMN involvement are also required to ensure patients with suspected ALS have timely access to appropriate therapeutic trials. The present review provides an analysis of current and recently developed assessment techniques, including novel imaging and electrophysiological approaches used to study corticomotoneuronal pathology in ALS. Copyright © 2016 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  15. 49 CFR 591.2 - Purpose.

    Science.gov (United States)

    2010-10-01

    ... OF TRANSPORTATION (CONTINUED) IMPORTATION OF VEHICLES AND EQUIPMENT SUBJECT TO FEDERAL SAFETY, BUMPER AND THEFT PREVENTION STANDARDS § 591.2 Purpose. The purpose of this part is to ensure that motor vehicles and motor vehicle equipment permanently imported into the United States conform with theft...

  16. 41 CFR 102-34.335 - How do I submit information to the General Services Administration (GSA) for the Federal Fleet...

    Science.gov (United States)

    2010-07-01

    ... (Continued) FEDERAL MANAGEMENT REGULATION PERSONAL PROPERTY 34-MOTOR VEHICLE MANAGEMENT Federal Fleet Report... Orders. In addition, the Office of Management and Budget (OMB) requires agency Fleet Managers and budget... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false How do I submit...

  17. National Motor Vehicle Crash Causation Survey (NMVCCS) - NMVCCS XML Case Viewer

    Data.gov (United States)

    Department of Transportation — The National Motor Vehicle Crash Causation Survey (NMVVCS) was a nationwide survey of crashes involving light passenger vehicles, with a focus on the factors related...

  18. 38 CFR 3.1606 - Transportation items.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Transportation items. 3... Burial Benefits § 3.1606 Transportation items. The transportation costs of those persons who come within... shipment. (6) Cost of transportation by common carrier including amounts paid as Federal taxes. (7) Cost of...

  19. MATHEMATICAL MODELING OF AC ELECTRIC POINT MOTOR

    Directory of Open Access Journals (Sweden)

    S. YU. Buryak

    2014-03-01

    Full Text Available Purpose. In order to ensure reliability, security, and the most important the continuity of the transportation process, it is necessary to develop, implement, and then improve the automated methods of diagnostic mechanisms, devices and rail transport systems. Only systems that operate in real time mode and transmit data on the instantaneous state of the control objects can timely detect any faults and thus provide additional time for their correction by railway employees. Turnouts are one of the most important and responsible components, and therefore require the development and implementation of such diagnostics system.Methodology. Achieving the goal of monitoring and control of railway automation objects in real time is possible only with the use of an automated process of the objects state diagnosing. For this we need to know the diagnostic features of a control object, which determine its state at any given time. The most rational way of remote diagnostics is the shape and current spectrum analysis that flows in the power circuits of railway automatics. Turnouts include electric motors, which are powered by electric circuits, and the shape of the current curve depends on both the condition of the electric motor, and the conditions of the turnout maintenance. Findings. For the research and analysis of AC electric point motor it was developed its mathematical model. The calculation of parameters and interdependencies between the main factors affecting the operation of the asynchronous machine was conducted. The results of the model operation in the form of time dependences of the waveform curves of current on the load on engine shaft were obtained. Originality. During simulation the model of AC electric point motor, which satisfies the conditions of adequacy was built. Practical value. On the basis of the constructed model we can study the AC motor in various mode of operation, record and analyze current curve, as a response to various changes

  20. Online Systems for Oversize and Overweight Freight Permitting and Motor Carrier Credentialing : Transportation Research Synthesis.

    Science.gov (United States)

    2017-09-01

    MnDOT uses two online systems implemented in the 1990s to issue and manage permits for oversize/overweight (OS/OW) freight and motor carrier credentials: - RouteBuilder, an OS/OW permitting system with a routing component. - Motor Carrier Information...

  1. 49 CFR 268.5 - Federal funding sources for the Maglev Deployment Program.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Federal funding sources for the Maglev Deployment... TECHNOLOGY DEPLOYMENT PROGRAM Overview § 268.5 Federal funding sources for the Maglev Deployment Program. (a) Federal Maglev Funds. Section 322 of Title 23 provides for the following funds for the Maglev Deployment...

  2. Motor control for a brushless DC motor

    Science.gov (United States)

    Peterson, William J. (Inventor); Faulkner, Dennis T. (Inventor)

    1985-01-01

    This invention relates to a motor control system for a brushless DC motor having an inverter responsively coupled to the motor control system and in power transmitting relationship to the motor. The motor control system includes a motor rotor speed detecting unit that provides a pulsed waveform signal proportional to rotor speed. This pulsed waveform signal is delivered to the inverter to thereby cause an inverter fundamental current waveform output to the motor to be switched at a rate proportional to said rotor speed. In addition, the fundamental current waveform is also pulse width modulated at a rate proportional to the rotor speed. A fundamental current waveform phase advance circuit is controllingly coupled to the inverter. The phase advance circuit is coupled to receive the pulsed waveform signal from the motor rotor speed detecting unit and phase advance the pulsed waveform signal as a predetermined function of motor speed to thereby cause the fundamental current waveform to be advanced and thereby compensate for fundamental current waveform lag due to motor winding reactance which allows the motor to operate at higher speeds than the motor is rated while providing optimal torque and therefore increased efficiency.

  3. 49 CFR 370.9 - Disposition of claims.

    Science.gov (United States)

    2010-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY... delay to property transported shall pay, decline, or make a firm compromise settlement offer in writing... the lost or damaged item as a base to apply a depreciation factor to arrive at the current actual...

  4. 49 CFR 384.214 - Reciprocity.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Reciprocity. 384.214 Section 384.214 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY... Reciprocity. The State shall allow any person to operate a CMV in the State who is not disqualified from...

  5. Selected legal and regulatory concerns affecting domestic energy transportation systems

    International Nuclear Information System (INIS)

    Schuller, C.R.

    1979-07-01

    This report provides assessments of eight legal and regulatory concerns that may affect energy material transportation in the US during the rest of the century: state authority to regulate nuclear materials transport, divestiture of petroleum pipelines from major integrated oil companies, problems affecting the natural gas transportation system, capabilities of energy transportation systems during emergencies, Federal coal pipeline legislation, ability of Federal agencies to anticipate railroad difficulties, abandonment of uneconomic railroad lines, and impact of the Panama Canal treaty upon US energy transportation

  6. Reduction of motor fuel consumption - Which recipes does the state have at its disposal?; Absenkung des Treibstoffverbrauchs: Welche Rezepte hat der Staat?

    Energy Technology Data Exchange (ETDEWEB)

    Volken, T.

    2008-07-01

    This presentation made at the Swiss 2008 research conference on traffic by Thomas Volken from the Energy Policy Section of the Swiss Federal Office of Energy SFOE takes a look at how motor-fuel consumption can be reduced. First of all, the present situation with regard to heating oil and motor fuels is examined and the gap between actual CO{sub 2} emissions from motor fuels and the target aimed for is discussed. Various legal and economical measures available are examined as are the promotion of technical innovation and motivational measures. The federal energy efficiency action plan and bonus/malus schemes are discussed and the environment label for cars is examined. Further, the situation in the European Union is discussed.

  7. 78 FR 3843 - Federal Motor Vehicle Safety Standards; New Pneumatic and Certain Specialty Tires

    Science.gov (United States)

    2013-01-17

    ... Approval Handbook for Japanese Certification, Safety Regulations for Road Vehicles, Technical Standards For... Technology Transfer and Advancement Act Section 12(d) of the National Technology Transfer and Advancement Act... vehicle safety, Motor vehicles, Rubber and rubber products, and Tires. In consideration of the foregoing...

  8. Executive Summary: EPA's Waiver Decision on California's Greenhouse Gas Emission Standards for New Motor Vehicles

    Science.gov (United States)

    This letter from EPA Administrator Stephen Johnson to Governor Schwarzenegger denies California's request for a waiver of Federal preemption for motor vehicle greenhouse gas emission standards submitted by the California Air Resources Board (CARB).

  9. Interplay of upper and lower motor neuron degeneration in amyotrophic lateral sclerosis.

    Science.gov (United States)

    de Carvalho, Mamede; Poliakov, Artiom; Tavares, Cristiano; Swash, Michael

    2017-11-01

    We studied motor unit recruitment to test a new method to identify motor unit firing rate (FR) variability. We studied 68 ALS patients, with and without upper neuron signs (UMN) in lower limbs, 24 patients with primary lateral sclerosis (PLS), 13 patients with spinal cord lesion and 39 normal subjects. All recordings were made from tibialis anterior muscles of normal strength. Subjects performed a very slight contraction in order to activate 2 motor units in each recording. 5-7 motor unit pairs were recorded in each subject. Mean consecutive differences (MCD) were calculated for each pair of potentials. The mean MCD for each muscle was estimated as the mean from the total number of pairs recorded. Ap valuemotor unit in a pair of units was markedly reduced in PLS, and in subjects with spinal cord lesions. These results support a lower threshold and reduced FR fluctuation in spinal motor neurons of spastic patients. This method can be developed for detection of UMN lesions. Copyright © 2017 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.

  10. 49 CFR 593.9 - Effect of affirmative determinations; lists.

    Science.gov (United States)

    2010-10-01

    ... TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) DETERMINATIONS THAT A VEHICLE NOT ORIGINALLY MANUFACTURED TO CONFORM TO THE FEDERAL MOTOR VEHICLE SAFETY STANDARDS IS ELIGIBLE FOR IMPORTATION... grant. (b) The Administrator publishes annually in the Federal Register a list of determinations made...

  11. Probing intracellular motor protein activity using an inducible cargo trafficking assay.

    Science.gov (United States)

    Kapitein, Lukas C; Schlager, Max A; van der Zwan, Wouter A; Wulf, Phebe S; Keijzer, Nanda; Hoogenraad, Casper C

    2010-10-06

    Although purified cytoskeletal motor proteins have been studied extensively with the use of in vitro approaches, a generic approach to selectively probe actin and microtubule-based motor protein activity inside living cells is lacking. To examine specific motor activity inside living cells, we utilized the FKBP-rapalog-FRB heterodimerization system to develop an in vivo peroxisomal trafficking assay that allows inducible recruitment of exogenous and endogenous kinesin, dynein, and myosin motors to drive specific cargo transport. We demonstrate that cargo rapidly redistributes with distinct dynamics for each respective motor, and that combined (antagonistic) actions of more complex motor combinations can also be probed. Of importance, robust cargo redistribution is readily achieved by one type of motor protein and does not require the presence of opposite-polarity motors. Simultaneous live-cell imaging of microtubules and kinesin or dynein-propelled peroxisomes, combined with high-resolution particle tracking, revealed that peroxisomes frequently pause at microtubule intersections. Titration and washout experiments furthermore revealed that motor recruitment by rapalog-induced heterodimerization is dose-dependent but irreversible. Our assay directly demonstrates that robust cargo motility does not require the presence of opposite-polarity motors, and can therefore be used to characterize the motile properties of specific types of motor proteins. Copyright © 2010 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  12. CO{sub 2} emissions reduction in the transport sector in Germany. Possible measures and their reduction potential. A status report by the Federal Environment Agency. Summary; CO{sub 2}-Emissionsminderung im Verkehr in Deutschland. Moegliche Massnahmen und ihre Minderungspotenziale. Ein Sachstandsbericht des Umweltbundesamtes

    Energy Technology Data Exchange (ETDEWEB)

    Rodt, Stefan; Georgi, Birgit; Huckestein, Burkhard; Moench, Lars; Herbener, Reinhard; Jahn, Helge; Koppe, Katharina; Lindmaier, Joern

    2010-03-15

    The Federal Environment Agency is therefore proposing a multitude of measures which have the potential to significantly reduce the CO{sub 2} emissions caused by transport and to thus achieve the German Federal Government's climate protection objectives. The measures target both freight and passenger transport and cover all transport modes (heavy goods vehicles, passenger cars, inland waterways, rail, air, pedestrians and bicycles). The Federal Environment Agency suggests a range of complementary measures in the following fields: - Traffic avoidance: Influencing / reducing transport demand and shortening distances. - Modal shift: Shifting transport to more environmentally friendly modes. - Optimising transport: Better utilisation of existing transport capacities. - Economic measures and - direct emission reduction on vehicles. In line with this, the measures and instruments proposed focus on the following areas: - Traffic-reducing through town planning and transport planning - Promoting environmentally friendly transport modes - Economic measures - Measures to improve vehicle and fleet efficiency - Consumer information and driving behaviour in road traffic The table below provides an overview of the measures and their reduction potential for the years 2020 and 2030. The calculated CO{sub 2} savings result from the divergence from the trend scenario which was calculated using the ''TREMOD'' model and is based on measures for the transport sector which have already been adopted. The potentials from the various individual measures proposed by the Federal Environment Agency cannot simply be added up, since the measures may be mutually reinforcing or reducing each others effect. For instance, if fewer heavy goods vehicles are on the road because of a switch to rail, this reduces the absolute reduction that could be achieved by the HGV fleet through e.g. the use of low-friction oils and low-rolling-resistance tyres. (orig.)

  13. CO{sub 2} emissions reduction in the transport sector in Germany. Possible measures and their reduction potential. A status report by the Federal Environment Agency. Summary; CO{sub 2}-Emissionsminderung im Verkehr in Deutschland. Moegliche Massnahmen und ihre Minderungspotenziale. Ein Sachstandsbericht des Umweltbundesamtes

    Energy Technology Data Exchange (ETDEWEB)

    Rodt, Stefan; Georgi, Birgit; Huckestein, Burkhard; Moench, Lars; Herbener, Reinhard; Jahn, Helge; Koppe, Katharina; Lindmaier, Joern

    2010-03-15

    The Federal Environment Agency is therefore proposing a multitude of measures which have the potential to significantly reduce the CO{sub 2} emissions caused by transport and to thus achieve the German Federal Government's climate protection objectives. The measures target both freight and passenger transport and cover all transport modes (heavy goods vehicles, passenger cars, inland waterways, rail, air, pedestrians and bicycles). The Federal Environment Agency suggests a range of complementary measures in the following fields: - Traffic avoidance: Influencing / reducing transport demand and shortening distances. - Modal shift: Shifting transport to more environmentally friendly modes. - Optimising transport: Better utilisation of existing transport capacities. - Economic measures and - direct emission reduction on vehicles. In line with this, the measures and instruments proposed focus on the following areas: - Traffic-reducing through town planning and transport planning - Promoting environmentally friendly transport modes - Economic measures - Measures to improve vehicle and fleet efficiency - Consumer information and driving behaviour in road traffic The table below provides an overview of the measures and their reduction potential for the years 2020 and 2030. The calculated CO{sub 2} savings result from the divergence from the trend scenario which was calculated using the ''TREMOD'' model and is based on measures for the transport sector which have already been adopted. The potentials from the various individual measures proposed by the Federal Environment Agency cannot simply be added up, since the measures may be mutually reinforcing or reducing each others effect. For instance, if fewer heavy goods vehicles are on the road because of a switch to rail, this reduces the absolute reduction that could be achieved by the HGV fleet through e.g. the use of low-friction oils and low-rolling-resistance tyres. (orig.)

  14. 23 CFR 970.214 - Federal lands congestion management system (CMS).

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Federal lands congestion management system (CMS). 970....214 Federal lands congestion management system (CMS). (a) For purposes of this section, congestion...) Develop criteria to determine when a CMS is to be implemented for a specific transportation system; and (2...

  15. 23 CFR 972.214 - Federal lands congestion management system (CMS).

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Federal lands congestion management system (CMS). 972... § 972.214 Federal lands congestion management system (CMS). (a) For purposes of this section, congestion... interference. For those FWS transportation systems that require a CMS, in both metropolitan and non...

  16. 48 CFR 247.370 - DD Form 1384, Transportation Control and Movement Document.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false DD Form 1384, Transportation Control and Movement Document. 247.370 Section 247.370 Federal Acquisition Regulations System... Transportation in Supply Contracts 247.370 DD Form 1384, Transportation Control and Movement Document. The...

  17. Using GPS-derived speed patterns for recognition of transport modes in adults.

    Science.gov (United States)

    Huss, Anke; Beekhuizen, Johan; Kromhout, Hans; Vermeulen, Roel

    2014-10-11

    Identification of active or sedentary modes of transport is of relevance for studies assessing physical activity or addressing exposure assessment. We assessed in a proof-of-principle study if speed as logged by GPSs could be used to identify modes of transport (walking, bicycling, and motorized transport: car, bus or train). 12 persons commuting to work walking, bicycling or with motorized transport carried GPSs for two commutes and recorded their mode of transport. We evaluated seven speed metrics: mean, 95th percentile of speed, standard deviation of the mean, rate-of-change, standardized-rate-of-change, acceleration and deceleration. We assessed which speed metric would best identify the transport mode using discriminant analyses. We applied cross validation and calculated agreement (Cohen's Kappa) between actual and derived modes of transport. Mode of transport was reliably classified whenever a person used a mode of transport for longer than one minute. Best results were observed when using the 95th percentile of speed, acceleration and deceleration (kappa 0.73). When we combined all motorized traffic into one category, kappa increased to 0.95. GPS-measured speed enable the identification of modes of transport. Given the current low costs of GPS devices and the built-in capacity of GPS tracking in most smartphones, the use of such devices in large epidemiological studies may facilitate the assessment of physical activity related to transport modes, or improve exposure assessment using automated travel mode detection.

  18. 48 CFR 46.314 - Transportation contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Transportation contracts... MANAGEMENT QUALITY ASSURANCE Contract Clauses 46.314 Transportation contracts. The contracting officer shall insert the clause at 52.246-14, Inspection of Transportation, in solicitations and contracts for freight...

  19. 23 CFR 710.511 - Transportation enhancements.

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Transportation enhancements. 710.511 Section 710.511 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT RIGHT-OF-WAY AND REAL ESTATE Property Acquisition Alternatives § 710.511 Transportation enhancements. (a...

  20. Unmasking the linear behaviour of slow motor adaptation to prolonged convergence.

    Science.gov (United States)

    Erkelens, Ian M; Thompson, Benjamin; Bobier, William R

    2016-06-01

    Adaptation to changing environmental demands is central to maintaining optimal motor system function. Current theories suggest that adaptation in both the skeletal-motor and oculomotor systems involves a combination of fast (reflexive) and slow (recalibration) mechanisms. Here we used the oculomotor vergence system as a model to investigate the mechanisms underlying slow motor adaptation. Unlike reaching with the upper limbs, vergence is less susceptible to changes in cognitive strategy that can affect the behaviour of motor adaptation. We tested the hypothesis that mechanisms of slow motor adaptation reflect early neural processing by assessing the linearity of adaptive responses over a large range of stimuli. Using varied disparity stimuli in conflict with accommodation, the slow adaptation of tonic vergence was found to exhibit a linear response whereby the rate (R(2)  = 0.85, P < 0.0001) and amplitude (R(2)  = 0.65, P < 0.0001) of the adaptive effects increased proportionally with stimulus amplitude. These results suggest that this slow adaptive mechanism is an early neural process, implying a fundamental physiological nature that is potentially dominated by subcortical and cerebellar substrates. © 2016 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  1. 49 CFR 591.3 - Applicability.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION (CONTINUED) IMPORTATION OF VEHICLES AND EQUIPMENT SUBJECT TO FEDERAL SAFETY, BUMPER AND THEFT PREVENTION STANDARDS § 591.3 Applicability. This part applies to any person offering a motor vehicle or item of motor vehicle equipment for importation into the United States. [55 FR 11378...

  2. 77 FR 33331 - Regulatory Guidance on the Applicability of Property-Carrier Hours-of-Service Rules to the...

    Science.gov (United States)

    2012-06-06

    ... manufacturer's facilities; (2) between a vehicle manufacturer and a dealership or purchaser; (3) between a dealership, or other entity selling or leasing the vehicle, and a purchaser or lessee; (4) to a motor carrier... Operation of Vehicles Designed to Transport Passengers AGENCY: Federal Motor Carrier Safety Administration...

  3. Padrões motores de escolares de oito a nove anos de idade da cidade de Santa Rosa, RS

    OpenAIRE

    Loi, Luiz Serafim de Mello

    1999-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Desportos. O desenvolvimento motor é um assunto que necessita maiores estudos, haja vista a importância cada vez maior do desenvolvimento pleno da criança, desde os primeiros anos de vida. Este estudo utilizando como Marco Referencial Teórico (MRT) o modelo de desenvolvimento motor de Gallahue & Ozmun (1998) teve por objetivo verificar o perfil motor de escolares de oito e nove anos de idade, da cidade de Santa Rosa...

  4. 49 CFR 393.90 - Buses, standee line or bar.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Buses, standee line or bar. 393.90 Section 393.90 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY... NECESSARY FOR SAFE OPERATION Miscellaneous Parts and Accessories § 393.90 Buses, standee line or bar. Except...

  5. 76 FR 46357 - Notice of Limitation on Claims Against Proposed Public Transportation Projects

    Science.gov (United States)

    2011-08-02

    ... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Notice of Limitation on Claims Against Proposed Public Transportation Projects AGENCY: Federal Transit Administration (FTA), DOT. ACTION: Notice... that FTA has taken final agency actions by issuing certain approvals for the public transportation...

  6. 48 CFR 47.403-2 - Air transport agreements between the United States and foreign governments.

    Science.gov (United States)

    2010-10-01

    ... Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TRANSPORTATION Air Transportation by U.S... attend, the use of a foreign-flag air carrier that provides transportation under an air transport... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Air transport agreements...

  7. NEW VECTORS OF THE MOTOR INSURANCE DEVELOPMENT IN UKRAINE

    Directory of Open Access Journals (Sweden)

    N. Prikazyuk

    2015-04-01

    Full Text Available The essence and features of different forms of motor insurance are studied. As investigated, the motor insurance is one of the most popular types of insurance in many countries, and continues its further quality development. It is stated that the following new vectors of development has been recently observed in developed countries: Internet sales are getting significantly prevalent along with the traditional channels of insurance distribution; insurers’ websites provide a wide range of online features in motor insurance; innovations in motor insurance based on the use of telematics, particularly the usage-based insurance, are widely spread. Basic types of motor insurance, which represent the domestic market, are analyzed. It was found that the share of motor insurance in the insurance market of Ukraine is significant. As established, the proportion of net premiums of motor insurance is decreasing, because its development is significantly influenced by economic factors. Measures, applied by insurance companies in the domestic market of motor insurance to attract new customers and retain the existing ones, are defined. In particular, insurers are trying to develop the implementation of insurance services online, and use possibilities offered by mobile technologies. It was found that the domestic market of motor insurance is characterized by a high level of fraud, that is why some innovative measures in the domestic and international motor insurance agreements are taken to decrease it, such as the introduction of mandatory registration of insurance agents, who have the right to perform mediatory activity in compulsory civil liability insurance of owners of motor vehicles (CCLIOMV, and procedures for contracting the international insurance “Green Card” agreements with simultaneous entering the information on concluded agreement into a unified centralized database of Motor (transport insurance bureau of Ukraine using the “Green Card online

  8. 41 CFR 102-34.290 - What forms do I use to report a crash involving a domestic fleet motor vehicle?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What forms do I use to report a crash involving a domestic fleet motor vehicle? 102-34.290 Section 102-34.290 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT...

  9. 49 CFR 30.15 - Restrictions on Federal public works projects.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Restrictions on Federal public works projects. 30... CONTRACTS TO SUPPLIERS OF GOODS AND SERVICES OF COUNTRIES THAT DENY PROCUREMENT MARKET ACCESS TO U.S. CONTRACTORS § 30.15 Restrictions on Federal public works projects. The contracting officer shall insert the...

  10. Optogenetically enhanced axon regeneration: motor versus sensory neuron-specific stimulation.

    Science.gov (United States)

    Ward, Patricia J; Clanton, Scott L; English, Arthur W

    2018-02-01

    Brief neuronal activation in injured peripheral nerves is both necessary and sufficient to enhance motor axon regeneration, and this effect is specific to the activated motoneurons. It is less clear whether sensory neurons respond in a similar manner to neuronal activation following peripheral axotomy. Further, it is unknown to what extent enhancement of axon regeneration with increased neuronal activity relies on a reflexive interaction within the spinal circuitry. We used mouse genetics and optical tools to evaluate the precision and selectivity of system-specific neuronal activation to enhance axon regeneration in a mixed nerve. We evaluated sensory and motor axon regeneration in two different mouse models expressing the light-sensitive cation channel, channelrhodopsin (ChR2). We selectively activated either sensory or motor axons using light stimulation combined with transection and repair of the sciatic nerve. Regardless of genotype, the number of ChR2-positive neurons whose axons had regenerated successfully was greater following system-specific optical treatment, with no effect on the number of ChR2-negative neurons (whether motor or sensory neurons). We conclude that acute system-specific neuronal activation is sufficient to enhance both motor and sensory axon regeneration. This regeneration-enhancing effect is likely cell autonomous. © 2018 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  11. Urban Road Transportation in Nigeria From 1960 To 2006 ...

    African Journals Online (AJOL)

    It was discovered that urban road transport system in Nigeria is inefficient and grossly inadequate even after 46 years of becoming independent from Colonial Rule. The paper suggested the construction of more motor-able roads within cities in order to increase the network; encourage increased public and private ...

  12. Draft evidence report : traumatic brain injury and commercial motor vehicle driver safety (comprehensive review).

    Science.gov (United States)

    2009-03-30

    Purpose of this evidence report is to address several key questions posed by the Federal Motor Carrier Safety Administration : Key question 1: What is the impact of traumatic brain injury on crash risk/driving performance? Key question 2: What factor...

  13. 49 CFR 392.1 - Scope of the rules in this part.

    Science.gov (United States)

    2010-10-01

    ... SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS DRIVING OF..., agents, representatives, and employees responsible for the management, maintenance, operation, or driving...

  14. 77 FR 31632 - Intent To Request Approval From OMB of One New Public Collection of Information: Highway Baseline...

    Science.gov (United States)

    2012-05-29

    ... and assets owned and operated by state departments of education and transportation. The Highway BASE... Transportation (DOT), Federal Motor Carrier Safety Administration (FMCSA), school bus, motorcoach companies... consistent road map for highway systems to address security and emergency program vulnerabilities. In...

  15. 41 CFR 101-39.200 - Scope.

    Science.gov (United States)

    2010-07-01

    ... FEDERAL PROPERTY MANAGEMENT REGULATIONS AVIATION, TRANSPORTATION, AND MOTOR VEHICLES 39-INTERAGENCY FLEET MANAGEMENT SYSTEMS 39.2-GSA Interagency Fleet Management System Services § 101-39.200 Scope. This subpart... Administration (GSA) Interagency Fleet Management System (IFMS). Local transportation services for Government...

  16. Automated processing of data on the use of motor vehicles in the Serbian Armed Forces

    Directory of Open Access Journals (Sweden)

    Nikola S. Osmokrović

    2012-10-01

    Full Text Available The main aim of introducing information technology into the armed forces is the automation of the management process. The management in movement and transport (M&T in our armed forces has been included in the process of automation from the beginning. For that reason, today we can speak about the automated processing of data on road traffic safety and on the use of motor vehicles. With regard to the overall development of the information system of the movement and transport service, the paper presents an information system of the M&T service for the processing of data on the use of motor vehicles. The main features, components and functions of the 'Vozila' application, which was specially developed for the automated processing of data on motor vehicle use, are explained in particular.

  17. 48 CFR 47.305-14 - Mode of transportation.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Mode of transportation. 47... CONTRACT MANAGEMENT TRANSPORTATION Transportation in Supply Contracts 47.305-14 Mode of transportation. Generally, solicitations shall not specify a particular mode of transportation or a particular carrier. If...

  18. 77 FR 26818 - Notice of Limitation on Claims Against Proposed Public Transportation Projects

    Science.gov (United States)

    2012-05-07

    ... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Notice of Limitation on Claims Against Proposed Public Transportation Projects AGENCY: Federal Transit Administration (FTA), DOT. ACTION: Notice... public transportation projects listed below. The actions on these projects, as well as the laws under...

  19. Motor contagion during human-human and human-robot interaction.

    Directory of Open Access Journals (Sweden)

    Ambra Bisio

    Full Text Available Motor resonance mechanisms are known to affect humans' ability to interact with others, yielding the kind of "mutual understanding" that is the basis of social interaction. However, it remains unclear how the partner's action features combine or compete to promote or prevent motor resonance during interaction. To clarify this point, the present study tested whether and how the nature of the visual stimulus and the properties of the observed actions influence observer's motor response, being motor contagion one of the behavioral manifestations of motor resonance. Participants observed a humanoid robot and a human agent move their hands into a pre-specified final position or put an object into a container at various velocities. Their movements, both in the object- and non-object- directed conditions, were characterized by either a smooth/curvilinear or a jerky/segmented trajectory. These trajectories were covered with biological or non-biological kinematics (the latter only by the humanoid robot. After action observation, participants were requested to either reach the indicated final position or to transport a similar object into another container. Results showed that motor contagion appeared for both the interactive partner except when the humanoid robot violated the biological laws of motion. These findings suggest that the observer may transiently match his/her own motor repertoire to that of the observed agent. This matching might mediate the activation of motor resonance, and modulate the spontaneity and the pleasantness of the interaction, whatever the nature of the communication partner.

  20. Motor contagion during human-human and human-robot interaction.

    Science.gov (United States)

    Bisio, Ambra; Sciutti, Alessandra; Nori, Francesco; Metta, Giorgio; Fadiga, Luciano; Sandini, Giulio; Pozzo, Thierry

    2014-01-01

    Motor resonance mechanisms are known to affect humans' ability to interact with others, yielding the kind of "mutual understanding" that is the basis of social interaction. However, it remains unclear how the partner's action features combine or compete to promote or prevent motor resonance during interaction. To clarify this point, the present study tested whether and how the nature of the visual stimulus and the properties of the observed actions influence observer's motor response, being motor contagion one of the behavioral manifestations of motor resonance. Participants observed a humanoid robot and a human agent move their hands into a pre-specified final position or put an object into a container at various velocities. Their movements, both in the object- and non-object- directed conditions, were characterized by either a smooth/curvilinear or a jerky/segmented trajectory. These trajectories were covered with biological or non-biological kinematics (the latter only by the humanoid robot). After action observation, participants were requested to either reach the indicated final position or to transport a similar object into another container. Results showed that motor contagion appeared for both the interactive partner except when the humanoid robot violated the biological laws of motion. These findings suggest that the observer may transiently match his/her own motor repertoire to that of the observed agent. This matching might mediate the activation of motor resonance, and modulate the spontaneity and the pleasantness of the interaction, whatever the nature of the communication partner.