A community translational research pilot grants program to facilitate community--academic partnerships: lessons from Colorado's clinical translational science awards.

Science.gov (United States)

Main, Deborah S; Felzien, Maret C; Magid, David J; Calonge, B Ned; O'Brien, Ruth A; Kempe, Allison; Nearing, Kathryn

2012-01-01

National growth in translational research has increased the need for practical tools to improve how academic institutions engage communities in research. One used by the Colorado Clinical and Translational Sciences Institute (CCTSI) to target investments in community-based translational research on health disparities is a Community Engagement (CE) Pilot Grants program. Innovative in design, the program accepts proposals from either community or academic applicants, requires that at least half of requested grant funds go to the community partner, and offers two funding tracks: One to develop new community-academic partnerships (up to $10,000), the other to strengthen existing partnerships through community translational research projects (up to $30,000). We have seen early success in both traditional and capacity building metrics: the initial investment of $272,742 in our first cycle led to over $2.8 million dollars in additional grant funding, with grantees reporting strengthening capacity of their community- academic partnerships and the rigor and relevance of their research.

Research Networking Systems: The State of Adoption at Institutions Aiming to Augment Translational Research Infrastructure.

Science.gov (United States)

Obeid, Jihad S; Johnson, Layne M; Stallings, Sarah; Eichmann, David

Fostering collaborations across multiple disciplines within and across institutional boundaries is becoming increasingly important with the growing emphasis on translational research. As a result, Research Networking Systems that facilitate discovery of potential collaborators have received significant attention by institutions aiming to augment their research infrastructure. We have conducted a survey to assess the state of adoption of these new tools at the Clinical and Translational Science Award (CTSA) funded institutions. Survey results demonstrate that most CTSA funded institutions have either already adopted or were planning to adopt one of several available research networking systems. Moreover a good number of these institutions have exposed or plan to expose the data on research expertise using linked open data, an established approach to semantic web services. Preliminary exploration of these publically-available data shows promising utility in assessing cross-institutional collaborations. Further adoption of these technologies and analysis of the data are needed, however, before their impact on cross-institutional collaboration in research can be appreciated and measured.

Review: Current Approaches to Business and Institutional Translation. Proceedings of the International Conference on Economic, Business, Financial and Institutional Translation

Directory of Open Access Journals (Sweden)

Miguel Tolosa Igualada

2016-08-01

Full Text Available Daniel Gallego-Hernández (ed.. Current Approaches to Business and Institutional Translation. Proceedings of the International Conference on Economic, Business, Financial and Institutional Translation / Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suíça: Peter Lang, 2015, 254 páginas. ISBN 978-3-0343-1656-9.

Translational science: past, present, and future.

Science.gov (United States)

Curry, Stephen H

2008-02-01

The concept of translational science is at least 15 years old. However, in its most recent incarnation, it represents the identification of a funding category designed to encourage academic participation in a critical stage of the drug discovery and product development process. It is hoped that this will make the process both shorter and more efficient. In this review, the author first considers the historical development of the pharmaceutical R&D process. The place of translational science in the process, the scientific techniques involved, and aspects of the business environment necessary for its success are then considered. Translational science does not displace preclinical development. Both concepts are relevant to the paramount importance of successfully and expeditiously bridging the gap between preclinical science and clinical testing, "from bench to bedside." Translational science is particularly likely to stimulate biomarker research in the universities and related business community and will probably give a modest boost to early clinical testing and commercialization of discoveries within the academic setting. Whether there will be a consequent improvement in the quality and efficiency of the overall process remains to be seen.

National Heart, Lung, and Blood Institute and the translation of cardiovascular discoveries into therapeutic approaches.

Science.gov (United States)

Galis, Zorina S; Black, Jodi B; Skarlatos, Sonia I

2013-04-26

The molecular causes of ≈4000 medical conditions have been described, yet only 5% have associated therapies. For decades, the average time for drug development through approval has taken 10 to 20 years. In recent years, the serious challenges that confront the private sector have made it difficult to capitalize on new opportunities presented by advances in genomics and cellular therapies. Current trends are disturbing. Pharmaceutical companies are reducing their investments in research, and biotechnology companies are struggling to obtain venture funds. To support early-stage translation of the discoveries in basic science, the National Institutes of Health and the National Heart, Lung, and Blood Institute have developed new approaches to facilitating the translation of basic discoveries into clinical applications and will continue to develop a variety of programs that create teams of academic investigators and industry partners. The goal of these programs is to maximize the public benefit of investment of taxpayer dollars in biomedical research and to lessen the risk required for industry partners to make substantial investments. This article highlights several examples of National Heart, Lung, and Blood Institute-initiated translational programs and National Institutes of Health translational resources designed to catalyze and enable the earliest stages of the biomedical product development process. The translation of latest discoveries into therapeutic approaches depends on continued federal funding to enhance the early stages of the product development process and to stimulate and catalyze partnerships between academia, industry, and other sources of capital.

Reengineering the National Clinical and Translational Research Enterprise: The Strategic Plan of the National Clinical and Translational Science Awards Consortium

Science.gov (United States)

Reis, Steven E.; Berglund, Lars; Bernard, Gordon R.; Califf, Robert M.; FitzGerald, Garret A.; Johnson, Peter C.

2009-01-01

Advances in human health require the efficient and rapid translation of scientific discoveries into effective clinical treatments; this process in turn depends upon observational data gathered from patients, communities, and public-health research that can be used to guide basic scientific investigation. Such bidirectional translational science, however, faces unprecedented challenges due to the rapid pace of scientific and technological development, as well as the difficulties of negotiating increasingly complex regulatory and commercial environments that overlap the research domain. Further, numerous barriers to translational science have emerged among the nation’s academic research centers, including basic structural and cultural impediments to innovation and collaboration, shortages of trained investigators, and inadequate funding. To address these serious and systemic problems, in 2006, the National Institutes of Health created the Clinical and Translational Science Awards (CTSA) program, which aims to catalyze the transformation of biomedical research at a national level, speeding the discovery and development of therapies, fostering collaboration, engaging communities, and training succeeding generations of clinical and translational researchers. The authors report in detail on the planning process, begun in 2008, that was used to engage stakeholders and to identify, refine, and ultimately implement the CTSA program’s overarching strategic goals. They also discuss the implications and likely impact of this strategic planning process as it is applied among the nation’s academic health centers. PMID:20182119

Strengthening the career development of clinical translational scientist trainees: a consensus statement of the Clinical Translational Science Award (CTSA) Research Education and Career Development Committees.

Science.gov (United States)

Meyers, Frederick J; Begg, Melissa D; Fleming, Michael; Merchant, Carol

2012-04-01

The challenges for scholars committed to successful careers in clinical and translational science are increasingly well recognized. The Education and Career Development (EdCD) of the national Clinical and Translational Science Award consortium gathered thought leaders to propose sustainable solutions and an agenda for future studies that would strengthen the infrastructure across the spectrum of pre- and postdoctoral, MD and PhD, scholars. Six consensus statements were prepared that include: (1) the requirement for career development of a qualitatively different investigator; (2) the implications of interdisciplinary science for career advancement including institutional promotion and tenure actions that were developed for discipline-specific accomplishments; (3) the need for long-term commitment of institutions to scholars; (4) discipline-specific curricula are still required but curricula designed to promote team work and interdisciplinary training will promote innovation; (5) PhD trainees have many pathways to career satisfaction and success; and (6) a centralized infrastructure to enhance and reward mentoring is required. Several themes cut across all of the recommendations including team science, innovation, and sustained institutional commitment. Implied themes include an effective and diverse job force and the requirement for a well-crafted public policy that supports continued investments in science education. © 2012 Wiley Periodicals, Inc.

Translation Meets Cognitive Science: The Imprint of Translation on Cognitive Processing

Science.gov (United States)

Rojo, Ana

2015-01-01

Translation has long played a role in linguistic and literary studies research. More recently, the theoretical and methodological concerns of process research have given translation an additional role in cognitive science. The interest in the cognitive aspects of translation has led scholars to turn to disciplines such as cognitive linguistics,…

Translating Dominant Institutional Logics in Practice

DEFF Research Database (Denmark)

Agger Nielsen, Jeppe; Jensen, Tina Blegind

In this paper we examine the proliferation of a new mobile technology in a structured setting of home care in Denmark, focusing on how actions at multiple levels interact to enable technology diffusion and institutionalization. The case study shows how a dominating field level logic...... that combining an institutional logic perspective with a translation perspective furthers our understanding of the malleability of institutional logics....

Translational science matters: forging partnerships between biomedical and behavioral science to advance the public's health.

Science.gov (United States)

Mensah, George A; Czajkowski, Susan M

2018-03-29

The prevention and effective treatment of many chronic diseases such as cardiovascular disease, cancer and diabetes are dependent on behaviors such as not smoking, adopting a physically-active lifestyle, eating a healthy diet, and adhering to prescribed medical and behavioral regimens. Yet adoption and maintenance of these behaviors pose major challenges for individuals, their families and communities, as well as clinicians and health care systems. These challenges can best be met through the integration of the biomedical and behavioral sciences that is achieved by the formation of strategic partnerships between researchers and practitioners in these disciplines to address pressing clinical and public health problems. The National Institutes of Health has supported a number of clinical trials and research initiatives that demonstrate the value of biomedical and behavioral science partnerships in translating fundamental discoveries into significant improvements in health outcomes. We review several such examples of collaborations between biomedical and behavioral researchers, describe key initiatives focused on advancing a transdisciplinary translational perspective, and outline areas which require insights, tools and findings from both the biomedical and behavioral sciences to advance the public's health.

Instituto Nacional de Ciência e Tecnologia em Medicina Translacional (INCT-TM: abordagens metodológicas National Science and Technology Institute for Translational Medicine (INCT-TM: advancing the field of translational medicine and mental health

Directory of Open Access Journals (Sweden)

Jaime E. C. Hallak

2010-03-01

, translational research offers an opportunity for applying the findings obtained from basic research to every-day clinical applications. The National Science and Technology Institute for Translational Medicine is comprised of six member institutions (Universidade Federal do Rio Grande do Sul, Universidade de São Paulo-Ribeirão Preto, Universidade Federal do Rio de Janeiro, Pontifícia Universidade Católica do Rio Grande do Sul, Universidade Estadual de Santa Catarina and a core facility that serves all centers. The objectives of the project are divided into four areas: Institutional, Research, Human Resources and Technology for the Community and Productive Sector. METHOD: In this manuscript, we describe some of the approaches used to attain the main objectives of the National Science and Technology Institute for Translational Medicine, which include the development of 1 animal models for bipolar disorder; 2 strategies to investigate neurobehavioral function and cognitive dysfunction associated with brain disorders; 3 experimental models of brain function and behavior, neuropsychiatric disorders, cell proliferation, and cancer; 4 Simulated Public Speaking and 5 Virtual reality simulation for inducing panic disorder and agoraphobia. CONCLUSION: The main focus of the National Science and Technology Institute for Translational Medicine is the development of more useful methods that allow for a better application of basic research-based knowledge to the medical field.

Training the next generation of research mentors: the University of California, San Francisco, Clinical & Translational Science Institute Mentor Development Program.

Science.gov (United States)

Feldman, Mitchell D; Huang, Laurence; Guglielmo, B Joseph; Jordan, Richard; Kahn, James; Creasman, Jennifer M; Wiener-Kronish, Jeanine P; Lee, Kathryn A; Tehrani, Ariane; Yaffe, Kristine; Brown, Jeanette S

2009-06-01

Mentoring is a critical component of career development and success for clinical translational science research faculty. Yet few programs train faculty in mentoring skills. We describe outcomes from the first two faculty cohorts who completed a Mentor Development Program (MDP) at UCSF. Eligibility includes having dedicated research time, expertise in a scientific area and a desire to be a lead research mentor. A post-MDP survey measured the program's impact on enhancement of five key mentoring skills, change in the Mentors-in-Training (MIT) self-rated importance of being a mentor to their career satisfaction, and overall confidence in their mentoring skills. Since 2007, 29 MITs participated in and 26 completed the MDP. Only 15% of the MITs reported any previous mentor training. Overall, 96% of MITs felt that participation in the MDP helped them to become better mentors. A majority reported a significant increase in confidence in mentoring skills and most reported an increased understanding of important mentoring issues at UCSF. MITs reported increased confidence in overall and specific mentoring skills after completion of the MDP. The MDP can serve as a model for other institutions to develop the next generation of clinical-translational research mentors.

78 FR 28601 - National Center for Advancing Translational Sciences; Request for Comment on Proposed Methods for...

Science.gov (United States)

2013-05-15

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Center for... resources that leverage basic research in support of translational science; and by developing partnerships...-newsletter, distribution of emails to NCATS stakeholder listservs, and announcements on NCATS Facebook page...

Translational medicine: science or wishful thinking?

Directory of Open Access Journals (Sweden)

Wehling Martin

2008-06-01

Full Text Available Abstract "Translational medicine" as a fashionable term is being increasingly used to describe the wish of biomedical researchers to ultimately help patients. Despite increased efforts and investments into R&D, the output of novel medicines has been declining dramatically over the past years. Improvement of translation is thought to become a remedy as one of the reasons for this widening gap between input and output is the difficult transition between preclinical ("basic" and clinical stages in the R&D process. Animal experiments, test tube analyses and early human trials do simply not reflect the patient situation well enough to reliably predict efficacy and safety of a novel compound or device. This goal, however, can only be achieved if the translational processes are scientifically backed up by robust methods some of which still need to be developed. This mainly relates to biomarker development and predictivity assessment, biostatistical methods, smart and accelerated early human study designs and decision algorithms among other features. It is therefore claimed that a new science needs to be developed called 'translational science in medicine'.

Multi-Dimensional Impact of the Public-Private Center for Translational Molecular Medicine (CTMM) in the Netherlands: Understanding New 21(st) Century Institutional Designs to Support Innovation-in-Society.

Science.gov (United States)

Steuten, Lotte M

2016-05-01

Knowledge translation is at the epicenter of 21st century life sciences and integrative biology. Several innovative institutional designs have been formulated to cultivate knowledge translation. One of these organizational innovations has been the Center for Translational Molecular Medicine (CTMM), a multi-million public-private partnership in the Netherlands. The CTMM aims to accelerate molecular diagnostics and imaging technologies to forecast disease susceptibilities in healthy populations and early diagnosis and personalized treatment of patients. This research evaluated CTMM's impact on scientific, translational, clinical, and economic dimensions. A pragmatic, operationally-defined process indicators approach was used. Data were gathered from CTMM administrations, through a CTMM-wide survey (n = 167) and group interviews. We found that the CTMM focused on disease areas with high human, clinical, and economic burden to society (i.e., oncology, cardiovascular, neurologic, infection, and immunity diseases). CTMM displayed a robust scientific impact that rests 15%-80% above international reference values regarding publication volume and impact. Technology translation to the clinic was accelerated, with >50% of projects progressing from pre-clinical development to clinical testing within 5 years. Furthermore, CTMM has generated nearly 1500 Full Time Equivalent (FTE) of translational R&D capacity. Its positive impact on translational, (future) clinical, and economic aspects is recognized across all surveyed stakeholders. As organizational innovation is increasingly considered critical to forge linkages between life sciences discoveries and innovation-in-society, lessons learned from this study may inform other institutions with similar objectives such as the Clinical and Translational Science Awards (CTSA) Program of the National Institutes of Health (NIH) in the United States.

Stimulating translational research

DEFF Research Database (Denmark)

Bentires-Alj, Mohamed; Rajan, Abinaya; van Harten, Wim

2015-01-01

Translational research leaves no-one indifferent and everyone expects a particular benefit. We as EU-LIFE (www.eu-life.eu), an alliance of 13 research institutes in European life sciences, would like to share our experience in an attempt to identify measures to promote translational research with...... without undermining basic exploratory research and academic freedom....

Science Translational Medicine – improving human health care worldwide by providing an interdisciplinary forum for idea exchange between basic scientists and clinical research practitioners

Directory of Open Access Journals (Sweden)

Forsythe, Katherine

2010-09-01

Full Text Available Science Translational Medicine’s mission is to improve human health care worldwide by providing a forum for communication and interdisciplinary idea exchange between basic scientists and clinical research practitioners from all relevant established and emerging disciplines. The weekly journal debuted in October 2009 and is published by the American Association for the Advancement of Science (AAAS, the publisher of Science and Science Signaling. The journal features peer-reviewed research articles, perspectives and commentary, and is guided by an international Advisory Board, led by Chief Scientific Adviser, Elias A. Zerhouni, M.D., former Director of the National Institutes of Health, and Senior Scientific Adviser, Elazer R. Edelman, M.D., Ph.D., Thomas D. and Virginia W. Cabot Professor of Health Sciences and Technology, Massachusetts Institute of Technology. The Science Translational Medicine editorial team is led by Katrina L. Kelner, Ph.D., AAAS. A profound transition is required for the science of translational medicine. Despite 50 years of advances in our fundamental understanding of human biology and the emergence of powerful new technologies, the rapid transformation of this knowledge into effective health measures is not keeping pace with the challenges of global health care. Creative experimental approaches, novel technologies, and new ways of conducting scientific explorations at the interface of established and emerging disciplines are now required to an unprecedented degree if real progress is to be made. To aid in this reinvention, Science and AAAS have created a new interdisciplinary journal, Science Translational Medicine. The following interview exemplefies the pioneering content found in Science Translational Medicine. It is an excerpt from a Podcast interview with Dr. Samuel Broder, former director of the National Cancer Institute and current Chief Medical Officer at Celera. The Podcast was produced in tangent with Dr

Assessment of and Response to Data Needs of Clinical and Translational Science Researchers and Beyond

Directory of Open Access Journals (Sweden)

Hannah F. Norton

2016-04-01

Full Text Available Objective and Setting: As universities and libraries grapple with data management and “big data,” the need for data management solutions across disciplines is particularly relevant in clinical and translational science (CTS research, which is designed to traverse disciplinary and institutional boundaries. At the University of Florida Health Science Center Library, a team of librarians undertook an assessment of the research data management needs of CTS researchers, including an online assessment and follow-up one-on-one interviews. Design and Methods: The 20-question online assessment was distributed to all investigators affiliated with UF’s Clinical and Translational Science Institute (CTSI and 59 investigators responded. Follow-up in-depth interviews were conducted with nine faculty and staff members. Results: Results indicate that UF’s CTS researchers have diverse data management needs that are often specific to their discipline or current research project and span the data lifecycle. A common theme in responses was the need for consistent data management training, particularly for graduate students; this led to localized training within the Health Science Center and CTSI, as well as campus-wide training. Another campus-wide outcome was the creation of an action-oriented Data Management/Curation Task Force, led by the libraries and with participation from Research Computing and the Office of Research. Conclusions: Initiating conversations with affected stakeholders and campus leadership about best practices in data management and implications for institutional policy shows the library’s proactive leadership and furthers our goal to provide concrete guidance to our users in this area.

Integrating Bioethics into Clinical and Translational Science Research: A Roadmap

Science.gov (United States)

Shapiro, Robyn S.; Layde, Peter M.

2008-01-01

Abstract Recent initiatives to improve human health emphasize the need to effectively and appropriately translate new knowledge gleaned from basic biomedical and behavioral research to clinical and community application. To maximize the beneficial impact of scientific advances in clinical practice and community health, and to guard against potential deleterious medical and societal consequences of such advances, incorporation of bioethics at each stage of clinical and translational science research is essential. At the earliest stage, bioethics input is critical to address issues such as whether to limit certain areas of scientific inquiry. Subsequently, bioethics input is important to assure not only that human subjects trials are conducted and reported responsibly, but also that results are incorporated into clinical and community practices in a way that promotes and protects bioethical principles. At the final stage of clinical and translational science research, bioethics helps to identify the need and approach for refining clinical practices when safety or other concerns arise. The framework we present depicts how bioethics interfaces with each stage of clinical and translational science research, and suggests an important research agenda for systematically and comprehensively assuring bioethics input into clinical and translational science initiatives. PMID:20443821

Polish Academy of Sciences. Institute of Biochemistry and Biophysics. Research Report 1998-1999

International Nuclear Information System (INIS)

2000-01-01

The report presented research activities of the Institute of Biochemistry and Biophysics, Polish Academy of Sciences, in 1998-1999. Research interests focus on: replication, mutagenesis and repair of DNA, regulation of gene expression, biosynthesis and post-translational modifications of proteins, gene sequencing and functional gene analysis, structure and function of enzymes, conformation of proteins and peptides, modeling of structures and prediction of function of proteins

Polish Academy of Sciences. Institute of Biochemistry and Biophysics. Research Report 1998-1999

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-07-01

The report presented research activities of the Institute of Biochemistry and Biophysics, Polish Academy of Sciences, in 1998-1999. Research interests focus on: replication, mutagenesis and repair of DNA, regulation of gene expression, biosynthesis and post-translational modifications of proteins, gene sequencing and functional gene analysis, structure and function of enzymes, conformation of proteins and peptides, modeling of structures and prediction of function of proteins.

Regulation of dynamin family proteins by post-translational

Indian Academy of Sciences (India)

2017-04-22

Apr 22, 2017 ... School of Biological Sciences, National Institute of Science Education and Research-. Bhubaneswar .... translational modifications provides the cell a dynamic and ..... Drp1 which confers cellular protection from mitochondrial.

How US institutional review boards decide when researchers need to translate studies.

Science.gov (United States)

Klitzman, Robert

2014-03-01

Informed consent is crucial in research, but potential participants may not all speak the same language, posing questions that have not been examined concerning decisions by institutional review boards (IRBs) and research ethics committees' (RECs) about the need for researchers to translate consent forms and other study materials. Sixty US IRBs (every fourth one in the list of the top 240 institutions by The National Institutes of Health funding) were contacted, and leaders (eg, chairs) from 34 (response rate=57%) and an additional 12 members and administrators were interviewed. IRBs face a range of problems about translation of informed consent documents, questionnaires and manuals-what, when and how to translate (eg, for how many or what proportion of potential subjects), why to do so and how to decide. Difficulties can arise about translation of specific words and of broader cultural concepts regarding processes of informed consent and research, especially in the developing world. In these decisions, IRBs weigh the need for autonomy (through informed consent) and justice (to ensure fair distribution of benefits and burdens of research) against practical concerns about costs to researchers. At times IRBs may have to compromise between these competing goals. These data, the first to examine when and how IRBs/RECs require researchers to translate materials, thus highlight a range of problems with which these committees struggle, suggesting a need for further normative and empirical investigation of these domains, and consideration of guidelines to help IRBs deal with these tensions.

Characteristics of Biostatistics, Epidemiology, and Research Design Programs in Institutions With Clinical and Translational Science Awards.

Science.gov (United States)

Rahbar, Mohammad H; Dickerson, Aisha S; Ahn, Chul; Carter, Rickey E; Hessabi, Manouchehr; Lindsell, Christopher J; Nietert, Paul J; Oster, Robert A; Pollock, Brad H; Welty, Leah J

2017-02-01

To learn the size, composition, and scholarly output of biostatistics, epidemiology, and research design (BERD) units in U.S. academic health centers (AHCs). Each year for four years, the authors surveyed all BERD units in U.S. AHCs that were members of the Clinical and Translational Science Award (CTSA) Consortium. In 2010, 46 BERD units were surveyed; in 2011, 55; in 2012, 60; and in 2013, 61. Response rates to the 2010, 2011, 2012, and 2013 surveys were 93.5%, 98.2%, 98.3%, and 86.9%, respectively. Overall, the size of BERD units ranged from 3 to 86 individuals. The median FTE in BERD units remained similar and ranged from 3.0 to 3.5 FTEs over the years. BERD units reported more availability of doctoral-level biostatisticians than doctoral-level epidemiologists. In 2011, 2012, and 2013, more than a third of BERD units provided consulting support on 101 to 200 projects. A majority of BERD units reported that between 25% and 75% (in 2011) and 31% to 70% (in 2012) of their consulting was to junior investigators. More than two-thirds of BERD units reported their contributions to the submission of 20 or more non-BERD grant or contract applications annually. Nearly half of BERD units reported 1 to 10 manuscripts submitted annually with a BERD practitioner as the first or corresponding author. The findings regarding BERD units provide a benchmark against which to compare BERD resources and may be particularly useful for institutions planning to develop new units to support programs such as the CTSA.

New associates | Announcements | Indian Academy of Sciences

Indian Academy of Sciences (India)

Translational Health Science and Technology Institute, Faridabad. Praveen Kumar Indian Institute of Science, Bengaluru. S Mishra Sabyashachi Mishra Indian Institute of Technology, Kharagpur. Jagannath Mondal TIFR Centre for Interdisciplinary Sciences, Hyderabad. Samrat Mondal Wildlife Institute of India, Dehradun.

OneFlorida Clinical Research Consortium: Linking a Clinical and Translational Science Institute With a Community-Based Distributive Medical Education Model.

Science.gov (United States)

Shenkman, Elizabeth; Hurt, Myra; Hogan, William; Carrasquillo, Olveen; Smith, Steven; Brickman, Andrew; Nelson, David

2018-03-01

Developing a national pragmatic clinical trial infrastructure is central to understanding the effectiveness of interventions applied under usual conditions and where people receive health care. To address this challenge, three Florida universities-the University of Florida Clinical and Translational Science Institute, Florida State University (with its community-based distributive medical education model), and the University of Miami-created (2010-2013) a statewide consortium, the OneFlorida Clinical Research Consortium, to support the conduct of pragmatic clinical trials and provide mentored research experiences for medical and graduate students in real-world practice settings. OneFlorida has four programs, which report to a steering committee with membership from each partner, community members, and the state Medicaid agency and Department of Health to ensure shared governance. The Clinical Research Program provides support to conduct research in the network and uses champions to engage community clinicians. The Citizen Scientist Program has community members who provide input on health topics of importance to them, study design, recruitment and retention strategies, and the interpretation of findings. The Data Trust Program contains electronic health record and health care claims data for 10.6 million Floridians. The Minority Education Program, in collaboration with three historically black colleges and universities, offers minority junior faculty mentoring in pragmatic clinical trials and implementation science. OneFlorida has implemented 27 studies with diverse patient populations and in diverse community practice settings. To identify evidence-based best practices from the clinical trials conducted in the network, foster their implementation, and expand research training opportunities.

NUCOR Institute for Life Sciences

International Nuclear Information System (INIS)

Anon.

1984-01-01

The article discusses the Nucor Institute for Life Sciences. The institute was previously part of Nucor, but is now an autonomous institute of the University of Pretoria. The task of the institute is to promote the application of radioisotopes and radiation techniques in medicine and biology. Research projects of the institute are shortly discussed

Knowledge Translation: Moving Proteomics Science to Innovation in Society.

Science.gov (United States)

Holmes, Christina; McDonald, Fiona; Jones, Mavis; Graham, Janice

2016-06-01

Proteomics is one of the pivotal next-generation biotechnologies in the current "postgenomics" era. Little is known about the ways in which innovative proteomics science is navigating the complex socio-political space between laboratory and society. It cannot be assumed that the trajectory between proteomics laboratory and society is linear and unidirectional. Concerned about public accountability and hopes for knowledge-based innovations, funding agencies and citizens increasingly expect that emerging science and technologies, such as proteomics, are effectively translated and disseminated as innovation in society. Here, we describe translation strategies promoted in the knowledge translation (KT) and science communication literatures and examine the use of these strategies within the field of proteomics. Drawing on data generated from qualitative interviews with proteomics scientists and ethnographic observation of international proteomics conferences over a 5-year period, we found that proteomics science incorporates a variety of KT strategies to reach knowledge users outside the field. To attain the full benefit of KT, however, proteomics scientists must challenge their own normative assumptions and approaches to innovation dissemination-beyond the current paradigm relying primarily on publication for one's scientific peers within one's field-and embrace the value of broader (interdisciplinary) KT strategies in promoting the uptake of their research. Notably, the Human Proteome Organization (HUPO) is paying increasing attention to a broader range of KT strategies, including targeted dissemination, integrated KT, and public outreach. We suggest that increasing the variety of KT strategies employed by proteomics scientists is timely and would serve well the omics system sciences community.

[Translational/regulatory science researches of NIHS for regenerative medicine and cellular therapy products].

Science.gov (United States)

Sato, Yoji

2014-01-01

In 2013, the Japanese Diet passed the Regenerative Medicine Promotion Act and the revisions to the Pharmaceutical Affairs Act, which was also renamed as the Therapeutic Products Act (TPA). One of the aims of the new/revised Acts is to promote the development and translation of and access to regenerative/cellular therapies. In the TPA, a product derived from processing cells is categorized as a subgroup of "regenerative medicine, cellular therapy and gene therapy products" (RCGPs), products distinct from pharmaceuticals and medical devices, allowing RCGPs to obtain a conditional and time- limited marketing authorization much earlier than that under the conventional system. To foster not only RCGPs, but also innovative pharmaceuticals and medical devices, the Ministry of Health, Labour and Welfare recently launched Translational Research Program for Innovative Pharmaceuticals, Medical Devices and RCGPs. This mini-review introduces contributions of the National Institute of Health Sciences (NIHS) to research projects on RCGPs in the Program.

The art of translating nutritional science into dietary guidance: history and evolution of the Dietary Guidelines for Americans.

Science.gov (United States)

Watts, Mary Lee; Hager, Mary H; Toner, Cheryl D; Weber, Jennifer A

2011-07-01

The United States government has published official Dietary Guidelines for Americans (DGA) since 1980 and has recently released the 2010 version. Serving as a foundational cornerstone for federal nutrition policy, the DGA embrace current nutritional science and translate it into practical guidance to enhance the overall health of Americans. This article reviews the history and process for developing the DGA, including the incorporation of sophisticated and systematic techniques for reviewing emerging evidence. It also explores issues related to implementation of the guidelines through federal policy, the food supply, and consumer knowledge and behavior. © 2011 International Life Sciences Institute.

Science, Science Signaling, and Science Translational Medicine – AAAS Special Collection on Cancer Research, March 2011

Directory of Open Access Journals (Sweden)

Forsythe, Katherine H.

2011-10-01

Full Text Available The National Cancer Act, signed in 1971, aimed to eliminate cancer deaths through a massive increase in research funding. The American Association for the Advancement of Science, the publisher of Science, Science Signaling, and Science Translational Medicine, observed the 40th anniversary of the Cancer Act in 2011, with special research articles and features, found in all three journals, on the state of cancer research 40 years later. This collection of articles explores both breakthroughs and the challenges in cancer research over the last four decades, and lets us know what we might expect in the future.

Online Localization of "Zooniverse" Citizen Science Projects--On the Use of Translation Platforms as Tools for Translator Education

Science.gov (United States)

Michalak, Krzysztof

2015-01-01

This paper aims at describing the way in which online translation platforms can facilitate the process of training translators. "Zooniverse," a website hosting a variety of citizen science projects in which everyone can take part, was used as an example of such a concept. The first section of this paper is focused on the history, idea…

Grounding new institutional theory on a micro-sociological and practice-based foundation - exploring models of translation

DEFF Research Database (Denmark)

Scheuer, John Damm

interested in explaining how and why ideas travel in and out of organizations and become institutionalized in organizational fields. More specifically the paper focuses on the way actor-network theory and the concept of translation have been translated by researchers trying to understand institutionalization......Institutional and more practice-based perspectives on organizing and change are increasingly being combined in order to understand the micro-processes on which institutional "orders" are built and changed. The aim of this paper is to analyze how this work is done in practice by researchers...... processes related to ideas that travel from one place in time and space to another. The paper suggests that combining the concept of translation and theories about institutional change will make it possible to ground macro-sociological claims about how ideas travel and become institutionalized...

What is the role of culture, diversity, and community engagement in transdisciplinary translational science?

Science.gov (United States)

Graham, Phillip W; Kim, Mimi M; Clinton-Sherrod, A Monique; Yaros, Anna; Richmond, Alan N; Jackson, Melvin; Corbie-Smith, Giselle

2016-03-01

Concepts of culture and diversity are necessary considerations in the scientific application of theory generation and developmental processes of preventive interventions; yet, culture and/or diversity are often overlooked until later stages (e.g., adaptation [T3] and dissemination [T4]) of the translational science process. Here, we present a conceptual framework focused on the seamless incorporation of culture and diversity throughout the various stages of the translational science process (T1-T5). Informed by a community-engaged research approach, this framework guides integration of cultural and diversity considerations at each phase with emphasis on the importance and value of "citizen scientists" being research partners to promote ecological validity. The integrated partnership covers the first phase of intervention development through final phases that ultimately facilitate more global, universal translation of changes in attitudes, norms, and systems. Our comprehensive model for incorporating culture and diversity into translational research provides a basis for further discussion and translational science development.

Translating biotechnology to knowledge-based innovation, peace, and development? Deploy a Science Peace Corps--an open letter to world leaders.

Science.gov (United States)

Hekim, Nezih; Coşkun, Yavuz; Sınav, Ahmet; Abou-Zeid, Alaa H; Ağırbaşlı, Mehmet; Akintola, Simisola O; Aynacıoğlu, Şükrü; Bayram, Mustafa; Bragazzi, Nicola Luigi; Dandara, Collet; Dereli, Türkay; Dove, Edward S; Elbeyli, Levent; Endrenyi, Laszlo; Erciyas, Kamile; Faris, Jack; Ferguson, Lynnette R; Göğüş, Fahrettin; Güngör, Kıvanç; Gürsoy, Mervi; Gürsoy, Ulvi K; Karaömerlioğlu, M Asım; Kickbusch, Ilona; Kılıç, Türker; Kılınç, Metin; Kocagöz, Tanıl; Lin, Biaoyang; LLerena, Adrián; Manolopoulos, Vangelis G; Nair, Bipin; Özkan, Bülent; Pang, Tikki; Sardaş, Şemra; Srivastava, Sanjeeva; Toraman, Cengiz; Üstün, Kemal; Warnich, Louise; Wonkam, Ambroise; Yakıcıer, Mustafa Cengiz; Yaşar, Ümit; Özdemir, Vural

2014-07-01

all men can stand adversity, but if you want to test a man's character, give him power." We therefore petition President Barack Obama, other world leaders, and international development agencies in positions of power around the globe, to consider deploying a Science Peace Corps to cultivate the essential (and presently missing) ties among life sciences, foreign policy, development, and peace agendas. A Science Peace Corps requires support by a credible and independent intergovernmental organization or development agency for funding, and arbitration in the course of volunteer work when the global versus local (glocal) value-based priorities and human rights intersect in synergy or conflict. In all, Science Peace Corps is an invitation to a new pathway for competence in 21(st) century science that is locally productive and globally competitive. It can open up scientific institutions to broader considerations and broader inputs, and thus cultivate vital translational science in a world sorely in need of solidarity and sustainable responses to the challenges of 21(st) century science and society.

The effects of a professional development geoscience education institute upon secondary school science teachers in Puerto Rico

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Llerandi Roman, Pablo Antonio

The geographic and geologic settings of Puerto Rico served as the context to develop a mixed methods investigation on: (1) the effects of a five-day long constructivist and field-based earth science education professional development institute upon 26 secondary school science teachers' earth science conceptual knowledge, perceptions of fieldwork, and beliefs about teaching earth science; and (2) the implementation of participants' newly acquired knowledge and experience in their science lessons at school. Qualitative data included questionnaires, semi-structured interviews, reflective journals, pre-post concept maps, and pre-post lesson plans. The Geoscience Concept Inventory and the Science Outdoor Learning Environment Inventory were translated into Spanish and culturally validated to collect quantitative data. Data was analyzed through a constructivist grounded theory methodology, descriptive statistics, and non-parametric methods. Participants came to the institute with serious deficiencies in earth science conceptual understanding, negative earth science teaching perspectives, and inadequate earth science teaching methodologies. The institute helped participants to improve their understanding of earth science concepts, content, and processes mostly related to the study of rocks, the Earth's structure, plate tectonics, maps, and the geology of Puerto Rico. Participants also improved their earth science teaching beliefs, perceptions on field-based education, and reflected on their environmental awareness and social responsibility. Participants greatly benefited from the field-based learning environment, inquiry-based teaching approaches modeled, the attention given to their affective domain, and reflections on their teaching practice as part of the institute's activities. The constructivist learning environment and the institute's contextualized and meaningful learning conceptual model were effective in generating interest and confidence in earth science teaching

Louis Figuier translated in Brazil: science popularizers in the last quarter of 19th century

Directory of Open Access Journals (Sweden)

Kaori Kodama

2017-06-01

Full Text Available This article aims to address aspects of the history of the divulgation of sciences in Brazil in the nineteenth century, through the analysis of the circulation of some translations into Portuguese of the works of French popularizer of science, Louis Figuier. His works, which were translated to different languages, received editions in Brazil and Portugal since late 1860. During this period, a model of popularization of science for non-specialists - working class, women and youth - with emphasis on applied science was gaining terrain. However, this model was also marked by limitations and discontinuities that reflect social issues in the passage to the twentieth century. This paper attempts to highlight the role of translators and editors, understood as mediators of science, whose projects of social reform was primarily focused in popular instruction.

Scientific Retreats with ‘Speed Dating’: Networking to Stimulate New Interdisciplinary Translational Research Collaborations and Team Science

Science.gov (United States)

Alberg, Anthony J.; Brady, Kathleen T.; Obeid, Jihad S.; Davis, Randal; Halushka, Perry V.

2016-01-01

To stimulate the formation of new interdisciplinary translational research teams and innovative pilot projects, the South Carolina Clinical & Translational Research (SCTR) Institute (South Carolina Clinical and Translational Science Award, CTSA) initiated biannual scientific retreats with “speed dating” networking sessions. Retreat themes were prioritized based on the following criteria; cross-cutting topic, unmet medical need, generation of novel technologies and methodologies. Each retreat commences with an external keynote speaker followed by a series of brief research presentations by local researchers focused on the retreat theme, articulating potential areas for new collaborations. After each session of presentations, there is a 30 minute scientific “speed dating” period during which the presenters meet with interested attendees to exchange ideas and discuss collaborations. Retreat attendees are eligible to compete for pilot project funds on the topic of the retreat theme. The 10 retreats held have had a total of 1004 participants, resulted in 61 pilot projects with new interdisciplinary teams, and 14 funded projects. The retreat format has been a successful mechanism to stimulate novel interdisciplinary research teams and innovative translational research projects. Future retreats will continue to target topics of cross-cutting importance to biomedical and public health research. PMID:27807146

Knowledge in motion: The cultural politics of modern science translations in Arabic.

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Elshakry, Marwa S

2008-12-01

This essay looks at the problem of the global circulation of modem scientific knowledge by looking at science translations in modern Arabic. In the commercial centers of the late Ottoman Empire, emerging transnational networks lay behind the development of new communities of knowledge, many of which sought to break with old linguistic and literary norms to redefine the basis of their authority. Far from acting as neutral purveyors of "universal truths," scientific translations thus served as key instruments in this ongoing process of sociopolitical and epistemological transformation and mediation. Fierce debates over translators' linguistic strategies and choices involved deliberations over the character of language and the nature of "science" itself. They were also crucially shaped by such geopolitical factors as the rise of European imperialism and anticolonial nationalism in the region. The essay concludes by arguing for the need for greater attention to the local factors involved in the translation of scientific concepts across borders.

The Tanenbaum Open Science Institute: Leading a Paradigm Shift at the Montreal Neurological Institute.

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Poupon, Viviane; Seyller, Annabel; Rouleau, Guy A

2017-08-30

The Montreal Neurological Institute is adopting an Open Science Policy that will be enacted by the Tanenbaum Open Science Institute. The aim is to accelerate the generation of knowledge and novel effective treatments for brain disorders by freeing science. Copyright © 2017 Elsevier Inc. All rights reserved.

Scientific retreats with 'speed dating': networking to stimulate new interdisciplinary translational research collaborations and team science.

Science.gov (United States)

Ranwala, Damayanthi; Alberg, Anthony J; Brady, Kathleen T; Obeid, Jihad S; Davis, Randal; Halushka, Perry V

2017-02-01

To stimulate the formation of new interdisciplinary translational research teams and innovative pilot projects, the South Carolina Clinical and Translational Research (SCTR) Institute (South Carolina Clinical and Translational Science Award, CTSA) initiated biannual scientific retreats with 'speed dating' networking sessions. Retreat themes were prioritized based on the following criteria; cross-cutting topic, unmet medical need, generation of novel technologies and methodologies. Each retreat begins with an external keynote speaker followed by a series of brief research presentations by local researchers focused on the retreat theme, articulating potential areas for new collaborations. After each session of presentations, there is a 30 min scientific 'speed dating' period during which the presenters meet with interested attendees to exchange ideas and discuss collaborations. Retreat attendees are eligible to compete for pilot project funds on the topic of the retreat theme. The 10 retreats held have had a total of 1004 participants, resulted in 61 pilot projects with new interdisciplinary teams, and 14 funded projects. The retreat format has been a successful mechanism to stimulate novel interdisciplinary research teams and innovative translational research projects. Future retreats will continue to target topics of cross-cutting importance to biomedical and public health research. Copyright © 2016 American Federation for Medical Research.

Do clinical and translational science graduate students understand linear regression? Development and early validation of the REGRESS quiz.

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Enders, Felicity

2013-12-01

Although regression is widely used for reading and publishing in the medical literature, no instruments were previously available to assess students' understanding. The goal of this study was to design and assess such an instrument for graduate students in Clinical and Translational Science and Public Health. A 27-item REsearch on Global Regression Expectations in StatisticS (REGRESS) quiz was developed through an iterative process. Consenting students taking a course on linear regression in a Clinical and Translational Science program completed the quiz pre- and postcourse. Student results were compared to practicing statisticians with a master's or doctoral degree in statistics or a closely related field. Fifty-two students responded precourse, 59 postcourse , and 22 practicing statisticians completed the quiz. The mean (SD) score was 9.3 (4.3) for students precourse and 19.0 (3.5) postcourse (P REGRESS quiz was internally reliable (Cronbach's alpha 0.89). The initial validation is quite promising with statistically significant and meaningful differences across time and study populations. Further work is needed to validate the quiz across multiple institutions. © 2013 Wiley Periodicals, Inc.

Ebola: translational science considerations.

Science.gov (United States)

Chiappelli, Francesco; Bakhordarian, Andre; Thames, April D; Du, Angela M; Jan, Allison L; Nahcivan, Melissa; Nguyen, Mia T; Sama, Nateli; Manfrini, Ercolano; Piva, Francesco; Rocha, Rafael Malagoli; Maida, Carl A

2015-01-16

and the disease from global translational science perspective.

National Institutes of Health addresses the science of diversity

Science.gov (United States)

Valantine, Hannah A.; Collins, Francis S.

2015-01-01

The US biomedical research workforce does not currently mirror the nation’s population demographically, despite numerous attempts to increase diversity. This imbalance is limiting the promise of our biomedical enterprise for building knowledge and improving the nation’s health. Beyond ensuring fairness in scientific workforce representation, recruiting and retaining a diverse set of minds and approaches is vital to harnessing the complete intellectual capital of the nation. The complexity inherent in diversifying the research workforce underscores the need for a rigorous scientific approach, consistent with the ways we address the challenges of science discovery and translation to human health. Herein, we identify four cross-cutting diversity challenges ripe for scientific exploration and opportunity: research evidence for diversity’s impact on the quality and outputs of science; evidence-based approaches to recruitment and training; individual and institutional barriers to workforce diversity; and a national strategy for eliminating barriers to career transition, with scientifically based approaches for scaling and dissemination. Evidence-based data for each of these challenges should provide an integrated, stepwise approach to programs that enhance diversity rapidly within the biomedical research workforce. PMID:26392553

National Institute of General Medical Sciences

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... Over Navigation Links National Institute of General Medical Sciences Site Map Staff Search My Order Search the ... NIGMS Website Research Funding Research Training News & Meetings Science Education About NIGMS Feature Slides View All Slides ...

Translating Nutrition Science into Policy as Witness and Actor

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The sustained effort to witness and participate in the targeted translation of nutritional science and policy forms the structure of this narrative. The memoir starts with an early career-directing experience with nutrition and cholera and proceeds with a long thread of interest in folic acid malabs...

Translational Research from an Informatics Perspective

Science.gov (United States)

Bernstam, Elmer; Meric-Bernstam, Funda; Johnson-Throop, Kathy A.; Turley, James P.; Smith, Jack W.

2007-01-01

Clinical and translational research (CTR) is an essential part of a sustainable global health system. Informatics is now recognized as an important en-abler of CTR and informaticians are increasingly called upon to help CTR efforts. The US National Institutes of Health mandated biomedical informatics activity as part of its new national CTR grant initiative, the Clinical and Translational Science Award (CTSA). Traditionally, translational re-search was defined as the translation of laboratory discoveries to patient care (bench to bedside). We argue, however, that there are many other kinds of translational research. Indeed, translational re-search requires the translation of knowledge dis-covered in one domain to another domain and is therefore an information-based activity. In this panel, we will expand upon this view of translational research and present three different examples of translation to illustrate the point: 1) bench to bedside, 2) Earth to space and 3) academia to community. We will conclude with a discussion of our local translational research efforts that draw on each of the three examples.

A distributed model: redefining a robust research subject advocacy program at the Harvard Clinical and Translational Science Center.

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Winkler, Sabune J; Cagliero, Enrico; Witte, Elizabeth; Bierer, Barbara E

2014-08-01

The Harvard Clinical and Translational Science Center ("Harvard Catalyst") Research Subject Advocacy (RSA) Program has reengineered subject advocacy, distributing the delivery of advocacy functions through a multi-institutional, central platform rather than vesting these roles and responsibilities in a single individual functioning as a subject advocate. The program is process-oriented and output-driven, drawing on the strengths of participating institutions to engage local stakeholders both in the protection of research subjects and in advocacy for subjects' rights. The program engages stakeholder communities in the collaborative development and distributed delivery of accessible and applicable educational programming and resources. The Harvard Catalyst RSA Program identifies, develops, and supports the sharing and distribution of expertise, education, and resources for the benefit of all institutions, with a particular focus on the frontline: research subjects, researchers, research coordinators, and research nurses. © 2014 Wiley Periodicals, Inc.

Translating Institutional Templates: A Historical Account of the Consequences of Importing Policing Models into Argentina

Directory of Open Access Journals (Sweden)

Matías Dewey

2017-01-01

Full Text Available This article focuses on the translation of the French and English law enforcement models into Argentina and analyzes its consequences in terms of social order. Whereas in the former two models the judiciary and police institutions originated in large-scale processes of historical consolidation, in the latter these institutions were implanted without the antecedents present in their countries of origin. The empirical references are Argentine police institutions, particularly the police of the Buenos Aires Province, observed at two moments in which the institutional import was particularly intense: towards the end of the nineteenth and beginning of the twentieth centuries, and at the end of the twentieth century. By way of tracing these processes of police constitution and reform, we show how new models of law enforcement and policing interacted with indigenous political structures and cultural frames, as well as how this constellation produced a social order in which legality and illegality are closely interwoven. The article is an attempt to go beyond the common observations regarding how an imported model failed; instead, it dissects the effects the translation actually produced and how the translated models transform into resources that reshape the new social order. A crucial element, the article shows, is that these resources can be instrumentalized according to »idiosyncrasies«, interests, and quotas of power.

Charting the Publication and Citation Impact of the NIH Clinical and Translational Science Awards (CTSA) Program From 2006 Through 2016.

Science.gov (United States)

Llewellyn, Nicole; Carter, Dorothy R; Rollins, Latrice; Nehl, Eric J

2018-01-02

The authors evaluated publication and citation patterns for articles supported by Clinical and Translational Science Awards (CTSA) hub investment over the first decade of the CTSA program. The aim was to elucidate a pivotal step in the translational process by providing an account of how time, hub maturity, and hub attributes were related to productivity and influence in the academic literature. In early 2017, the authors collected bibliometric data from PubMed, Web of Science InCites, and NIH iCite for articles citing any CTSA hub grants published from hub inception through 2016. They compiled data on publication and citation rates, and indices of relative citation impact aggregated by hub funding year cohort. They compared hub-level bibliometric activity by multi- versus single-institution structure and total monetary award sums, compiled from NIH RePORTER. From 2006-2016, CTSA hubs supported over 66,000 publications, with publication rates accelerating as hubs matured. These publications accumulated over 1.2 million citations, with some articles cited over 1,000 times. Indices of relative citation impact indicated that CTSA-supported publications were cited more than twice as often as expected for articles of their publication years and disciplines. Multi-institutional hubs and those awarded higher grant sums exhibited significantly higher publication and citation activity. The CTSA program is yielding a robust and growing body of influential research findings with consistently high indices of relative citation impact. Preliminary evidence suggests multi-institutional collaborations and more monetary resources are associated with elevated bibliometric activity, and therefore, may be worth their investment.

Science education in a bilingual class: problematising a translational practice

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Ünsal, Zeynep; Jakobson, Britt; Molander, Bengt-Olov; Wickman, Per-Olof

2016-10-01

In this article we examine how bilingual students construe relations between everyday language and the language of science. Studies concerning bilingual students language use in science class have mainly been conducted in settings where both the teacher and the students speak the same minority language. In this study data was collected in a class consisting of students aged 13-14. All students had Turkish as their minority language, whereas the teacher's minority language was Bosnian. The class was observed when they were working with acids and bases. In addition, the students were interviewed in groups. They were asked about how they use their languages during science lessons and then asked to describe and explain scientific phenomena and processes that had been a part of the observed lessons. For the analysis, practical epistemology analysis and the theory of translanguaging were used. The results show how the students' everyday language repertoire may limit their possibilities to make meaning of science. In particular, the teacher's practice of facilitating and supporting students' understanding of science content by relating it to concrete examples took another direction since the everyday words he used were not a part of the students' language repertoire. The study also shows how the students used their minority language as a resource to translate words from Swedish to Turkish in order to proceed with the science activities. However, translating scientific concepts was problematic and led to the students' descriptions of the concepts not being in line with how they are viewed in science. Finally, the study also demonstrates how monolingual exams may limit bilingual students' achievements in science. The study contributes by presenting and discussing circumstances that need to be taken into consideration when planning and conducting science lessons in classes where the teacher and the student do not share the same minority language.

Translational nutrition research at UC-Davis – the key role of the clinical and translational science center

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To better understand the facility and equipment needs for human clinical nutrition research the New York Academy of Sciences presented a symposium. This paper is the result of that symposium and provides information into how clinical nutrition research is conducted at the Clinical and Translational ...

The Ethics of Translational Science: Imagining Public Benefit in Gene-Environment Interaction Research

Directory of Open Access Journals (Sweden)

Sara L. Ackerman

2017-06-01

Full Text Available Biomedical research is increasingly informed by expectations of “translation,” which call for the production of scientific knowledge that can be used to create services and products that improve health outcomes. In this paper, we ask how translation, in particular the idea of social responsibility, is understood and enacted in the post-genomic life sciences. Drawing on theories examining what constitutes “good science,” and interviews with 35 investigators who study the role of gene-environment interactions in the etiology of cancer, diabetes, and cardiovascular disease, we describe the dynamic and unsettled ethics of translational science through which the expected social value of scientific knowledge about complex disease causation is negotiated. To describe how this ethics is formed, we first discuss the politics of knowledge production in interdisciplinary research collectives. Researchers described a commitment to working across disciplines to examine a wide range of possible causes of disease, but they also pointed to persistent disciplinary and ontological divisions that rest on the dominance of molecular conceptions of disease risk. The privileging of molecular-level causation shapes and constrains the kinds of knowledge that can be created about gene-environment interactions. We then turn to scientists’ ideas about how this knowledge should be used, including personalized prevention strategies, targeted therapeutics, and public policy interventions. Consensus about the relative value of these anticipated translations was elusive, and many scientists agreed that gene-environment interaction research is part of a shift in biomedical research away from considering important social, economic, political and historical causes of disease and disease disparities. We conclude by urging more explicit engagement with questions about the ethics of translational science in the post-genomic life sciences. This would include a consideration

Data Science for Institutional and Organizational Economics

NARCIS (Netherlands)

Prüfer, Jens; Prüfer, Patricia

2018-01-01

To which extent can data science methods – such as machine learning, text analysis, or sentiment analysis – push the research frontier in the social sciences? This essay briefly describes the most prominent data science techniques that lend themselves to analyses of institutional and organizational

Information Science Research Institute. Quarterly progress report

Energy Technology Data Exchange (ETDEWEB)

Nartker, T.A.

1994-06-30

This is a second quarter 1194 progress report on the UNLV Information Science Research Institute. Included is symposium activity; staff activity; document analysis program; text retrieval program; institute activity; and goals.

A mentor development program for clinical translational science faculty leads to sustained, improved confidence in mentoring skills.

Science.gov (United States)

Feldman, Mitchell D; Steinauer, Jody E; Khalili, Mandana; Huang, Laurence; Kahn, James S; Lee, Kathryn A; Creasman, Jennifer; Brown, Jeanette S

2012-08-01

Mentorship is crucial for academic productivity and advancement for clinical and translational (CT) science faculty. However, little is known about the long-term effects of mentor training programs. The University of California, San Francisco (UCSF), Clinical and Translational Science Institute launched a Mentor Development Program (MDP) in 2007 for CT faculty. We report on an evaluation of the first three cohorts of graduates from the MDP. In 2010, all Mentors in Training (MITs) who completed the MDP from 2007 to 2009 (n= 38) were asked to complete an evaluation of their mentoring skills and knowledge; all MITs (100%) completed the evaluation. Two-thirds of MDP graduates reported that they often apply knowledge, attitudes, or skills obtained in the MDP to their mentoring. Nearly all graduates (97%) considered being a mentor important to their career satisfaction. Graduates were also asked about the MDP's impact on specific mentoring skills; 95% agreed that the MDP helped them to become a better mentor and to focus their mentoring goals. We also describe a number of new initiatives to support mentoring at UCSF that have evolved from the MDP. To our knowledge, this is the first evaluation of the long-term impact of a mentor training program for CT researchers. © 2012 Wiley Periodicals, Inc.

Translation Theory 'Translated'

DEFF Research Database (Denmark)

Wæraas, Arild; Nielsen, Jeppe

2016-01-01

Translation theory has proved to be a versatile analytical lens used by scholars working from different traditions. On the basis of a systematic literature review, this study adds to our understanding of the ‘translations’ of translation theory by identifying the distinguishing features of the most...... common theoretical approaches to translation within the organization and management discipline: actor-network theory, knowledge-based theory, and Scandinavian institutionalism. Although each of these approaches already has borne much fruit in research, the literature is diverse and somewhat fragmented......, but also overlapping. We discuss the ways in which the three versions of translation theory may be combined and enrich each other so as to inform future research, thereby offering a more complete understanding of translation in and across organizational settings....

Translating Biotechnology to Knowledge-Based Innovation, Peace, and Development? Deploy a Science Peace Corps—An Open Letter to World Leaders

Science.gov (United States)

Abou-Zeid, Alaa H.; Ağırbaşlı, Mehmet; Akintola, Simisola O.; Aynacıoğlu, Şükrü; Bayram, Mustafa; Bragazzi, Nicola Luigi; Dandara, Collet; Dereli, Türkay; Dove, Edward S.; Elbeyli, Levent; Endrenyi, Laszlo; Erciyas, Kamile; Faris, Jack; Ferguson, Lynnette R.; Göğüş, Fahrettin; Güngör, Kıvanç; Gürsoy, Mervi; Gürsoy, Ulvi K.; Karaömerlioğlu, M. Asım; Kickbusch, Ilona; Kılıç, Türker; Kılınç, Metin; Kocagöz, Tanıl; Lin, Biaoyang; LLerena, Adrián; Manolopoulos, Vangelis G.; Nair, Bipin; Özkan, Bülent; Pang, Tikki; Şardaş, Semra; Srivastava, Sanjeeva; Toraman, Cengiz; Üstün, Kemal; Warnich, Louise; Wonkam, Ambroise; Yakıcıer, Mustafa Cengiz; Yaşar, Ümit

2014-01-01

, “nearly all men can stand adversity, but if you want to test a man's character, give him power.” We therefore petition President Barack Obama, other world leaders, and international development agencies in positions of power around the globe, to consider deploying a Science Peace Corps to cultivate the essential (and presently missing) ties among life sciences, foreign policy, development, and peace agendas. A Science Peace Corps requires support by a credible and independent intergovernmental organization or development agency for funding, and arbitration in the course of volunteer work when the global versus local (glocal) value-based priorities and human rights intersect in synergy or conflict. In all, Science Peace Corps is an invitation to a new pathway for competence in 21st century science that is locally productive and globally competitive. It can open up scientific institutions to broader considerations and broader inputs, and thus cultivate vital translational science in a world sorely in need of solidarity and sustainable responses to the challenges of 21st century science and society. “Let me say in conclusion, this University is not maintained by its alumni, or by the state, merely to help its graduates have an economic advantage in the life struggle. There is certainly a greater purpose, and I'm sure you recognize it. Therefore, I do not apologize for asking for your support in this campaign.” President John F. Kennedy On the occasion of the Peace Corps Campaign, On the steps of the University of Michigan Union PMID:24955641

Translating Current Science into Materials for High School via a Scientist-Teacher Partnership

Science.gov (United States)

Brown, Julie C.; Bokor, Julie R.; Crippen, Kent J.; Koroly, Mary Jo

2014-01-01

Scientist-teacher partnerships are a unique form of professional development that can assist teachers in translating current science into classroom instruction by involving them in meaningful collaborations with university researchers. However, few reported models aim to directly alter science teachers' practices by supporting them in the…

Translating Behavioral Science into Practice: A Framework to Determine Science Quality and Applicability for Police Organizations.

Science.gov (United States)

McClure, Kimberley A; McGuire, Katherine L; Chapan, Denis M

2018-05-07

Policy on officer-involved shootings is critically reviewed and errors in applying scientific knowledge identified. Identifying and evaluating the most relevant science to a field-based problem is challenging. Law enforcement administrators with a clear understanding of valid science and application are in a better position to utilize scientific knowledge for the benefit of their organizations and officers. A recommended framework is proposed for considering the validity of science and its application. Valid science emerges via hypothesis testing, replication, extension and marked by peer review, known error rates, and general acceptance in its field of origin. Valid application of behavioral science requires an understanding of the methodology employed, measures used, and participants recruited to determine whether the science is ready for application. Fostering a science-practitioner partnership and an organizational culture that embraces quality, empirically based policy, and practices improves science-to-practice translation. © 2018 American Academy of Forensic Sciences.

Building a Science Software Institute: Synthesizing the Lessons Learned from the ISEES and WSSI Software Institute Conceptualization Efforts

Science.gov (United States)

Idaszak, R.; Lenhardt, W. C.; Jones, M. B.; Ahalt, S.; Schildhauer, M.; Hampton, S. E.

2014-12-01

The NSF, in an effort to support the creation of sustainable science software, funded 16 science software institute conceptualization efforts. The goal of these conceptualization efforts is to explore approaches to creating the institutional, sociological, and physical infrastructures to support sustainable science software. This paper will present the lessons learned from two of these conceptualization efforts, the Institute for Sustainable Earth and Environmental Software (ISEES - http://isees.nceas.ucsb.edu) and the Water Science Software Institute (WSSI - http://waters2i2.org). ISEES is a multi-partner effort led by National Center for Ecological Analysis and Synthesis (NCEAS). WSSI, also a multi-partner effort, is led by the Renaissance Computing Institute (RENCI). The two conceptualization efforts have been collaborating due to the complementarity of their approaches and given the potential synergies of their science focus. ISEES and WSSI have engaged in a number of activities to address the challenges of science software such as workshops, hackathons, and coding efforts. More recently, the two institutes have also collaborated on joint activities including training, proposals, and papers. In addition to presenting lessons learned, this paper will synthesize across the two efforts to project a unified vision for a science software institute.

Developing a translational ecology workforce

Science.gov (United States)

Schwartz, Mark W.; Hiers, J. Kevin; Davis, Frank W.; Garfin, Gregg; Jackson, Stephen T.; Terando, Adam J.; Woodhouse, Connie A.; Morelli, Toni; Williamson, Matthew A.; Brunson, Mark W.

2017-01-01

We define a translational ecologist as a professional ecologist with diverse disciplinary expertise and skill sets, as well as a suitable personal disposition, who engages across social, professional, and disciplinary boundaries to partner with decision makers to achieve practical environmental solutions. Becoming a translational ecologist requires specific attention to obtaining critical non‐scientific disciplinary breadth and skills that are not typically gained through graduate‐level education. Here, we outline a need for individuals with broad training in interdisciplinary skills, use our personal experiences as a basis for assessing the types of interdisciplinary skills that would benefit potential translational ecologists, and present steps that interested ecologists may take toward becoming translational. Skills relevant to translational ecologists may be garnered through personal experiences, informal training, short courses, fellowships, and graduate programs, among others. We argue that a translational ecology workforce is needed to bridge the gap between science and natural resource decisions. Furthermore, we argue that this task is a cooperative responsibility of individuals interested in pursuing these careers, educational institutions interested in training scientists for professional roles outside of academia, and employers seeking to hire skilled workers who can foster stakeholder‐engaged decision making.

The Metropolitan Studies Institute at USC Upstate: Translational Research that Drives Community Decision-Making

Science.gov (United States)

Brady, Kathleen

2012-01-01

The Metropolitan Studies Institute (MSI) at the University of South Carolina Upstate (USC Upstate) demonstrates a robust and unique record of community impact through community indicators research and other translational research. The MSI's work drives programmatic priorities and funding decisions, generates revenue, and increases the community's…

Summer Institute for Physical Science Teachers

Science.gov (United States)

Maheswaranathan, Ponn; Calloway, Cliff

2007-04-01

A summer institute for physical science teachers was conducted at Winthrop University, June 19-29, 2006. Ninth grade physical science teachers at schools within a 50-mile radius from Winthrop were targeted. We developed a graduate level physics professional development course covering selected topics from both the physics and chemistry content areas of the South Carolina Science Standards. Delivery of the material included traditional lectures and the following new approaches in science teaching: hands-on experiments, group activities, computer based data collection, computer modeling, with group discussions & presentations. Two experienced master teachers assisted us during the delivery of the course. The institute was funded by the South Carolina Department of Education. The requested funds were used for the following: faculty salaries, the University contract course fee, some of the participants' room and board, startup equipment for each teacher, and indirect costs to Winthrop University. Startup equipment included a Pasco stand-alone, portable Xplorer GLX interface with sensors (temperature, voltage, pH, pressure, motion, and sound), and modeling software (Wavefunction's Spartan Student and Odyssey). What we learned and ideas for future K-12 teacher preparation initiatives will be presented.

Bridging the Divide: Translating Landsat Research Into Usable Science

Science.gov (United States)

Rocchio, L. E.; Davis, A. L.

2006-12-01

Science has long served humankind. Breakthroughs in medicine have increased longevity and advances in technology have made modern-day conveniences possible. Yet, social benefits begotten by the environmental sciences, although critical for the survival of humanity, have not always been as widely recognized or used. To benefit today's rapidly growing population, the divides between environmental research, applied environmental science, and use of this information by decision makers must be bridged. Lessons about the translation from research to usable science can be learned from the four decades of Landsat history, and these lessons can serve as useful models for bridging the gaps between new technology, scientific research, and the use of that research and technology in real-world problem solving. In 1965, William Pecora, then-director of the U.S. Geological Survey, proposed the idea of a remote sensing satellite program to gather facts about natural resources of Earth. For the next seven years, an intense campaign showing the depth and diversity of satellite imagery applications was waged. This led to the 1972 launch of the first civilian land-observing satellite, Landsat 1. By 1975, successful application research based on Landsat 1 imagery prompted then-NASA Administrator Dr. James Fletcher to proclaim that if one space age development would save the world, it would be Landsat and its successor satellites. Thirty-four years of continual Landsat imaging and related-research has lead to the implementation of many socially beneficial applications, such as improved water management techniques, crop insurance fraud reduction, illicit crop inventories, natural disaster relief planning, continent-scale carbon estimates, and extensive cartographic advances. Despite these successes, the challenge of translating Landsat research into realized social benefits remains. Even in this geospatially-savvy era, the utility of Landsat largely escapes policymakers. Here, in an

Toward enhanced learning of science: An educational scheme for informal science institutions

Science.gov (United States)

Suzuki, Midori

Current educational operation for informal science institutions tend to be based on the staff's experience and intuition rather than on educational theories or research findings. This status study sought research evidence for an educational scheme to give informal science institutions. Evidence for this scheme came from surveys to determine specific circumstances of educational operations and visitor behaviors. The Provus discrepancy model, seeking gaps between the actual and desired states, guided this investigation of how informal science education institution staff view the nature and status of educational operations. Another investigation sought visitors' views of the effectiveness of the main idea for exhibit understanding (n=68 for each group of with the main idea and without the main idea), effective labels (n=68), expectations toward on-site lessons(n=22 and 65 for student groups, and n=2 for teachers), and possibilities for assessments of museum operations. Institutional data were collected via a web portal, with a separate site created for administrators (n=41), exhibit developers (n=21), and program planners (n=35). The survey asked about actual and desired states in terms of goals and roles of staff, contents of exhibits and programs, assessment, and professional development. The four visitor surveys were administered individually at the North Carolina Museum of Natural Sciences. The institutional survey found that most institutions focus on attitudinal reinforcement rather than visitor learning, do not overtly value research or long-term assessment, and value partnerships with K-12 schools more than other groups. It is also clarified that the staff do not have a clear vision of the nature or function of an operations manuals. Large gaps were found between the actual and desired states in terms of assessment (administrators, exhibit developers, and program planners), professional development (exhibit developers and program planners), and partnerships

On using ethical principles of community-engaged research in translational science.

Science.gov (United States)

Khodyakov, Dmitry; Mikesell, Lisa; Schraiber, Ron; Booth, Marika; Bromley, Elizabeth

2016-05-01

The transfer of new discoveries into both clinical practice and the wider community calls for reliance on interdisciplinary translational teams that include researchers with different areas of expertise, representatives of health care systems and community organizations, and patients. Engaging new stakeholders in research, however, calls for a reconsideration or expansion of the meaning of ethics in translational research. We explored expert opinion on the applicability of ethical principles commonly practiced in community-engaged research (CEnR) to translational research. To do so, we conducted 2 online, modified-Delphi panels with 63 expert stakeholders who iteratively rated and discussed 9 ethical principles commonly used in CEnR in terms of their importance and feasibility for use in translational research. The RAND/UCLA appropriateness method was used to analyze the data and determine agreement and disagreement among participating experts. Both panels agreed that ethical translational research should be "grounded in trust." Although the academic panel endorsed "culturally appropriate" and "forthcoming with community about study risks and benefits," the mixed academic-community panel endorsed "scientifically valid" and "ready to involve community in interpretation and dissemination" as important and feasible principles of ethical translational research. These findings suggest that in addition to protecting human subjects, contemporary translational science models need to account for the interests of, and owe ethical obligations to, members of the investigative team and the community at large. Copyright © 2016 Elsevier Inc. All rights reserved.

Translational Science Project Team Managers: Qualitative Insights and Implications from Current and Previous Postdoctoral Experiences.

Science.gov (United States)

Wooten, Kevin C; Dann, Sara M; Finnerty, Celeste C; Kotarba, Joseph A

2014-07-01

The development of leadership and project management skills is increasingly important to the evolution of translational science and team-based endeavors. Team science is dependent upon individuals at various stages in their careers, inclusive of postdocs. Data from case histories, as well as from interviews with current and former postdocs, and those supervising postdocs, indicate six essential tasks required of project managers in multidisciplinary translational teams, along with eight skill-related themes critical to their success. To optimize the opportunities available and to ensure sequential development of team project management skills, a life cycle model for the development of translational team skills is proposed, ranging from graduate trainees, postdocs, assistant professors, and finally to mature scientists. Specific goals, challenges and project management roles and tasks are recommended for each stage for the life cycle.

UNLV Information Science Research Institute. Quarterly progress report

International Nuclear Information System (INIS)

Nartker, T.A.

1994-01-01

This document summarizes the activities and progress for the 1994 Fall quarter for the UNLV Information Science Research Institute. Areas covered include: Symposium activity, Staff activity, Document analysis program, Text-retrieval program, and Institute activity

UNLV Information Science Research Institute. Quarterly progress report

Energy Technology Data Exchange (ETDEWEB)

Nartker, T.A.

1994-12-31

This document summarizes the activities and progress for the 1994 Fall quarter for the UNLV Information Science Research Institute. Areas covered include: Symposium activity, Staff activity, Document analysis program, Text-retrieval program, and Institute activity.

Lost in Translation

Science.gov (United States)

Lass, Wiebke; Reusswig, Fritz

2014-05-01

Lost in Translation? Introducing Planetary Boundaries into Social Systems. Fritz Reusswig, Wiebke Lass Potsdam Institute for Climate Impact Research, Potsdam, Germany Identifying and quantifying planetary boundaries by interdisciplinary science efforts is a challenging task—and a risky one, as the 1972 Limits to Growth publication has shown. Even if we may be assured that scientific understanding of underlying processes of the Earth system has significantly improved since then, the challenge of translating these findings into the social systems of the planet remains crucial for any kind of action, and in many respects far more challenging. We would like to conceptualize what could also be termed a problem of coupling social and natural systems as a nested set of social translation processes, well aware of the limited applicability of the language-related translation metaphor. Societies must, first, perceive these boundaries, and they have to understand their relevance. This includes, among many other things, the organization of transdisciplinary scientific cooperation. They will then have to translate this understood perception into possible actions, i.e. strategies for different local bodies, actors, and institutional settings. This implies a lot of 'internal' translation processes, e.g. from the scientific subsystem to the mass media, the political and the economic subsystem. And it implies to develop subsystem-specific schemes of evaluation for these alternatives, e.g. convincing narratives, cost-benefit analyses, or ethical legitimacy considerations. And, finally, societies do have to translate chosen action alternatives into monitoring and evaluation schemes, e.g. for agricultural production or renewable energies. This process includes the continuation of observing and re-analyzing the planetary boundary concept itself, as a re-adjustment of these boundaries in the light of new scientific insights cannot be excluded. Taken all together, societies may well

Translation and Cross-Cultural Adaptation of the Danish Version: Wheelchair Users Shoulder Pain Index (WUSPI)

DEFF Research Database (Denmark)

Larsen, Camilla Marie; Hansen, Sabrina S.; Hansen, Line S.

Translation and Cross-Cultural Adaptation of the Danish Version: Wheelchair Users Shoulder Pain Index (WUSPI). Larsen CM1,2; Hansen SS2; Hansen LH2; Bruun P1; Juul-Kristensen B1,3. 1Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark. 2Health Sciences Research...

Health Extension and Clinical and Translational Science: An Innovative Strategy for Community Engagement.

Science.gov (United States)

Kaufman, Arthur; Rhyne, Robert L; Anastasoff, Juliana; Ronquillo, Francisco; Nixon, Marnie; Mishra, Shiraz; Poola, Charlene; Page-Reeves, Janet; Nkouaga, Carolina; Cordova, Carla; Larson, Richard S

Health Extension Regional Officers (HEROs) through the University of New Mexico Health Sciences Center (UNMHSC) help to facilitate university-community engagement throughout New Mexico. HEROs, based in communities across the state, link priority community health needs with university resources in education, service, and research. Researchers' studies are usually aligned with federal funding priorities rather than with health priorities expressed by communities. To help overcome this misalignment, the UNM Clinical and Translational Science Center (CTSC) provides partial funding for HEROs to bridge the divide between research priorities of UNMHSC and health priorities of the state's communities. A bidirectional partnership between HEROs and CTSC researchers was established, which led to: 1) increased community engaged studies through the CTSC, 2) the HERO model itself as a subject of research, 3) a HERO-driven increase in local capacity in scholarship and grant writing, and 4) development of training modules for investigators and community stakeholders on community-engaged research. As a result, 5 grants were submitted, 4 of which were funded, totaling $7,409,002.00, and 3 research articles were published. Health extension can serve as a university-funded, community-based bridge between community health needs and Clinical and Translational Science Award (CTSA) research capacity, opening avenues for translational research. © Copyright 2017 by the American Board of Family Medicine.

Teaching Translational Research to Medical Students: The New York University School of Medicine's Master's of Science in Clinical Investigation Dual‐Degree Program

Science.gov (United States)

Pillinger, Michael; Plottel, Claudia S.; Galeano, Claudia; Maddalo, Scott; Hochman, Judith S.; Cronstein, Bruce N.; Gold‐von Simson, Gabrielle

2015-01-01

Abstract To develop the next generation of translational investigators, New York University School of Medicine (NYUSOM) and the NYU‐NYC Health and Hospitals Corporation Clinical and Translational Science Institute (NYU‐HHC CTSI) developed the Master's of Science in Clinical Investigation dual‐degree (MD/MSCI) program. This 5‐year program dedicates 1 year to coursework and biomedical research, followed by a medical school/research overlap year, to prepare students for academic research careers. This paper details the MD/MSCI program's curriculum and approach to mentorship, describes the research/professional interests of students, and reports student productivity. In the first 4 years of the program (2010–2014) 20 students were matriculated; 7 (35%) were women, and 12 (60%) research projects were in surgical specialties. To date, 14 students have applied to residency, and half pursued surgical residency programs. Our students have produced 68 accepted abstracts, 15 abstracts in submission, 38 accepted papers, and 24 papers in submission. Despite the time‐limited nature of this program, additional training in research design and implementation has promoted a high level of productivity. We conclude that dual‐degree training in medicine and translational research is feasible for medical students and allows for meaningful participation in valuable projects. Follow‐up is warranted to evaluate the academic trajectory of these students. PMID:26365704

Teaching Translational Research to Medical Students: The New York University School of Medicine's Master's of Science in Clinical Investigation Dual-Degree Program.

Science.gov (United States)

Gillman, Jennifer; Pillinger, Michael; Plottel, Claudia S; Galeano, Claudia; Maddalo, Scott; Hochman, Judith S; Cronstein, Bruce N; Gold-von Simson, Gabrielle

2015-12-01

To develop the next generation of translational investigators, New York University School of Medicine (NYUSOM) and the NYU-NYC Health and Hospitals Corporation Clinical and Translational Science Institute (NYU-HHC CTSI) developed the Master's of Science in Clinical Investigation dual-degree (MD/MSCI) program. This 5-year program dedicates 1 year to coursework and biomedical research, followed by a medical school/research overlap year, to prepare students for academic research careers. This paper details the MD/MSCI program's curriculum and approach to mentorship, describes the research/professional interests of students, and reports student productivity. In the first 4 years of the program (2010-2014) 20 students were matriculated; 7 (35%) were women, and 12 (60%) research projects were in surgical specialties. To date, 14 students have applied to residency, and half pursued surgical residency programs. Our students have produced 68 accepted abstracts, 15 abstracts in submission, 38 accepted papers, and 24 papers in submission. Despite the time-limited nature of this program, additional training in research design and implementation has promoted a high level of productivity. We conclude that dual-degree training in medicine and translational research is feasible for medical students and allows for meaningful participation in valuable projects. Follow-up is warranted to evaluate the academic trajectory of these students. © 2015 Wiley Periodicals, Inc.

Translational Epidemiology in Psychiatry

Science.gov (United States)

Weissman, Myrna M.; Brown, Alan S.; Talati, Ardesheer

2012-01-01

Translational research generally refers to the application of knowledge generated by advances in basic sciences research translated into new approaches for diagnosis, prevention, and treatment of disease. This direction is called bench-to-bedside. Psychiatry has similarly emphasized the basic sciences as the starting point of translational research. This article introduces the term translational epidemiology for psychiatry research as a bidirectional concept in which the knowledge generated from the bedside or the population can also be translated to the benches of laboratory science. Epidemiologic studies are primarily observational but can generate representative samples, novel designs, and hypotheses that can be translated into more tractable experimental approaches in the clinical and basic sciences. This bedside-to-bench concept has not been explicated in psychiatry, although there are an increasing number of examples in the research literature. This article describes selected epidemiologic designs, providing examples and opportunities for translational research from community surveys and prospective, birth cohort, and family-based designs. Rapid developments in informatics, emphases on large sample collection for genetic and biomarker studies, and interest in personalized medicine—which requires information on relative and absolute risk factors—make this topic timely. The approach described has implications for providing fresh metaphors to communicate complex issues in interdisciplinary collaborations and for training in epidemiology and other sciences in psychiatry. PMID:21646577

Understanding Career Success and Its Contributing Factors for Clinical and Translational Investigators

Science.gov (United States)

Robinson, Georgeanna F.W.B.; Schwartz, Lisa S.; DiMeglio, Linda A.; Ahluwalia, Jasjit S.; Gabrilove, Janice L.

2015-01-01

Purpose To understand the factors that facilitate career success for career development awardees in clinical and translational science and to reconceptualize understanding of career success for this population. Method In 2013–2014, the authors conducted semi-structured interviews with former NIH KL2 or K12 scholars from nine Clinical and Translational Science Award-funded institutions. Participants either had or had not secured independent funding at least two years after the end of their last K award. Questions covered the factors that facilitate or hinder junior investigators’ transition to independent funding. Interviews were recorded and transcribed and the transcripts analyzed thematically. Results Forty individuals participated, with equal representation by men and women and by independently and not independently funded investigators. Personal factors that facilitated success included: networks, persistence and resilience, initiative, autonomy, and personal and professional balance. Organizational factors included: appropriate mentorship, protected research time, and institutional resources and support. Even independently funded participants described challenges regarding career direction. Five participants without independent funding modeled a broad spectrum of successful career paths, having assumed leadership positions not reliant on grant funding. Alternative definitions of career success included: improving public health, enjoying work, seeing mentees succeed, and receiving external acknowledgement of successes. Conclusions Awareness of the factors that facilitate or hinder career success can help junior faculty, mentors, and institutional leaders support career development in clinical and translational science. New definitions of career success are needed, as are career paths for faculty who want to engage in research in roles other than principal investigator. PMID:26509600

Behavioral and Social Sciences at the National Institutes of Health: adoption of research findings in health research and practice as a scientific priority.

Science.gov (United States)

Riley, William T

2017-06-01

The National Institutes of Health's Office of Behavioral and Social Sciences Research (OBSSR) recently released its Strategic Plan for 2017 to 2021. This plan highlights three scientific priorities: (1) improve the synergy of basic and applied behavioral and social sciences research, (2) enhance and promote the research infrastructure, methods, and measures needed to support a more cumulative and integrated approach to behavioral and social sciences research, and (3) facilitate the adoption of behavioral and social sciences research findings in health research and in practice. This commentary focuses on the challenges and opportunities to facilitate the adoption of research findings in health research and in practice. In addition to the ongoing NIH support for dissemination and implementation (D&I) research, we must address transformative challenges and opportunities such as better disseminating and implementing D&I research, merging research and practice, adopting more rigorous and diverse methods and measures for both D&I and clinical trials research, evaluating technological-based delivery of interventions, and transitioning from minimally adaptable intervention packages to planned adaptations rooted in behavior change principles. Beyond translation into practice and policy, the OBSSR Strategic Plan also highlights the need for translation of behavioral and social science findings into the broader biomedical research enterprise.

Translational plant proteomics: A perspective

NARCIS (Netherlands)

Agrawal, G.K.; Pedreschi, R.; Barkla, B.J.; Bindschedler, L.V.; Cramer, R.; Sarkar, A.; Renaut, J.; Job, D.; Rakwal, R.

2012-01-01

Translational proteomics is an emerging sub-discipline of the proteomics field in the biological sciences. Translational plant proteomics aims to integrate knowledge from basic sciences to translate it into field applications to solve issues related but not limited to the recreational and economic

7th International Summer Institute in Surface Science

CERN Document Server

Howe, Russell

1986-01-01

This volume contains review articles which were written by the invited speak­ ers of the seventh International Summer Institute in Surface Science (ISISS), held at the University of Wisconsin - Milwaukee in July 1985. The form of ISISS is a set of tutorial review lectures presented over a one-week period by internationally recognized experts on various aspects of surface science. Each speaker is asked, in addition, to write a review article on his lecture topic. No single volume in the series Chemistry and Physics of Solid Surfaces can possibly cover the entire field of modern surface science. However, the series as a whole is intended to provide experts and students alike with a comprehensive set of reviews and literature references, particularly empha­ sizing the gas-solid interface. The collected articles from previous Summer Institutes have been published under the following titles: Surface Science: Recent Progress and Perspectives, Crit. Rev. Solid State Sci. 4, 125-559 (1974) Chemistry and Physics of ...

Institute for Computer Applications in Science and Engineering (ICASE)

Science.gov (United States)

1984-01-01

Research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics, numerical analysis and computer science during the period April 1, 1983 through September 30, 1983 is summarized.

Translational ecology for hydrogeology.

Science.gov (United States)

Schlesinger, William H

2013-01-01

Translational ecology--a special discipline aimed to improve the accessibility of science to policy makers--will help hydrogeologists contribute to the solution of pressing environmental problems. Patterned after translational medicine, translational ecology is a partnership to ensure that the right science gets done in a timely fashion, so that it can be communicated to those who need it. © 2013, National Ground Water Association.

Petroleum Science and Technology Institute with the TeXas Earth and Space Science (TXESS) Revolution

Science.gov (United States)

Olson, H. C.; Olson, J. E.; Bryant, S. L.; Lake, L. W.; Bommer, P.; Torres-Verdin, C.; Jablonowski, C.; Willis, M.

2009-12-01

The TeXas Earth and Space Science (TXESS) Revolution, a professional development program for 8th- thru 12th-grade Earth Science teachers, presented a one-week Petroleum Science and Technology Institute at The University of Texas at Austin campus. The summer program was a joint effort between the Jackson School of Geosciences and the Department of Petroleum and Geosystems Engineering. The goal of the institute was to focus on the STEM components involved in the petroleum industry and to introduce teachers to the larger energy resources theme. The institute kicked off with a welcoming event and tour of a green, energy-efficient home (LEED Platinum certified) owned by one of the petroleum engineering faculty. Tours of the home included an introduction to rainwater harvesting, solar energy, sustainable building materials and other topics on energy efficiency. Classroom topics included drilling technology (including a simulator lab and an overview of the history of the technology), energy use and petroleum geology, well-logging technology and interpretation, reservoir engineering and volumetrics (including numerous labs combining chemistry and physics), risk assessment and economics, carbon capture and storage (CO2 sequestration technology) and hydraulic fracturing. A mid-week field trip included visiting the Ocean Star offshore platform in Galveston, the Weiss Energy Hall at the Houston Museum of Science and Schlumberger (to view 3-D visualization technology) in Houston. Teachers remarked that they really appreciated the focused nature of the institute and especially found the increased use of mathematics both a tool for professional growth, as well as a challenge for them to use more math in their science classes. STEM integration was an important feature of the summer institute, and teachers found the integration of science (earth sciences, geophysics), technology, engineering (petroleum, chemical and reservoir) and mathematics particularly valuable. Pre

The Francis Crick Institute.

Science.gov (United States)

Peters, Keith; Smith, Jim

2017-04-01

The Francis Crick Institute Laboratory, opened in 2016, is supported by the Medical Research Council, Cancer Research UK, the Wellcome Trust, and University College London, King's College London and Imperial College London. The emphasis on research training and early independence of gifted scientists in a multidisciplinary environment provides unique opportunities for UK medical science, including clinical and translational research. © Royal College of Physicians 2017. All rights reserved.

Translational Environmental Research: Improving the Usefulness and Usability of Research Results

Science.gov (United States)

Garfin, G.

2008-12-01

policy changes and improve general health. Parallels in environmental sciences might be TER1 (translational environmental research 1), basic insights regarding environmental processes and relationships between environmental changes and their causes. TER2, applied environmental research, development of best practices, and development of decision support tools. TER3, might include usability and impact evaluation, effective outreach and implementation of best practices, and application of research insights to public policy and institutional change. According to the medical literature, and in anecdotal evidence from end-to-end environmental science, decision-maker and public involvement in these various forms of engaged research decreases the lag between scientific discovery and implementation of discoveries in operational practices, information tools, and organizational and public policies.

Political Science Careers at Comprehensive Universities: Building Balanced Careers at "Greedy" Institutions

Science.gov (United States)

Hendrickson, Ryan C.; Mueller, Melinda A.; Strand, Jonathan R.

2011-01-01

A considerable amount of research exists about political science careers at community colleges and liberal arts institutions, as well as about training and hiring practices across different types of institutions. However, there is virtually no commentary available on political science careers at comprehensive institutions, where a significant…

Multidirectional Translation of Environmental Health Science in Community Settings: The Case of Oxidative Stress Pathways.

Science.gov (United States)

Sampson, Natalie R; Tetteh, Myra M; Schulz, Amy J; Ramirez, Erminia; Wilkins, Donele; de Majo, Ricardo; Mentz, Graciela; Johnson-Lawrence, Vicki

2016-01-01

Translation of environmental health science in vulnerable communities is particularly important to promote public health and reduce health inequities. We describe a structured, multidirectional process used to develop a suite of health promotion tools (e.g., fact sheets, video, maps) documenting patterning of local air pollution sources and availability of antioxidant-rich foods in Detroit, Michigan as factors that jointly affect oxidative stress (OS). OS underlies many pathological processes associated with air pollution, including asthma, metabolic syndrome, cancer, diabetes, and obesity. This translational effort involved a 2-year dialogue among representatives from community-based and environmental organizations, health service providers, and academic researchers. This dialogue led to development of tools, as well as new opportunities to inform related policies and research. Through this example, we highlight how collaborative partnerships can enhance multidirectional dialogue to inform translation of environmental health science by promoting consideration of multilevel risk factors, local priorities and context, and diverse audiences.

76 FR 7225 - National Institute of Environmental Health Sciences; Notice of Meetings

Science.gov (United States)

2011-02-09

... Environmental Health Sciences; Notice of Meetings Pursuant to section 10(a) of the Federal Advisory Committee..., National Institute of Environmental Health Sciences, 615 Davis Dr., KEY615/3112, Research Triangle Park, NC..., National Institute of Environmental Health Sciences, 615 Davis Dr., KEY615/3112, Research Triangle Park, NC...

Pluripotent stem cells in translation: a Food and Drug Administration-National Institutes of Health collaboration.

Science.gov (United States)

Kleitman, Naomi; Rao, Mahendra S; Owens, David F

2013-07-01

Recently, the U.S. Food and Drug Administration (FDA), the U.S. National Institutes of Health, and the stem cell research community have collaborated on a series of workshops that address moving pluripotent stem cell therapies into the clinic. The first two workshops in the series focused on preclinical science, and a third, future workshop will focus on clinical trials. This summary addresses major points from both of the recent preclinically focused meetings. When entering into a therapeutics developmental program based on pluripotent cells, investigators must make decisions at the very early stages that will have major ramifications during later phases of development. Presentations and discussions from both invited participants and FDA staff described the need to characterize and document the quality, variability, and suitability of the cells and commercial reagents used at every translational stage. This requires consideration of future regulatory requirements, ranging from donor eligibility of the original source material to the late-stage manufacturing protocols. Federal, industrial, and academic participants agreed that planning backward is the best way to anticipate what evidence will be needed to justify human testing of novel therapeutics and to eliminate wasted efforts.

Toward actionable science: Empowering ecologists to engage in the process of translation through decision-maker and stakeholder partnerships

Science.gov (United States)

Enquist, C.; Jackson, S. T.; Garfin, G. M.

2017-12-01

Translational ecology is an approach by which ecologists, stakeholders, and decision-makers work collaboratively to develop and deliver ecological research that, ideally, results in actionable science that leads to improved environmental decision-making. We analyzed a diverse array of real-world case studies and distilled six principles that characterize the practice of translational ecology: communication, commitment, collaboration, engagement, process, and decision-framing. In this talk, we highlight a subset of the case studies that illustrate these principles. Notably, we found that translational ecology is distinct from both basic and applied ecological research. As a practice, the approach deliberately extends research beyond theory or opportunistic applications, motivated by a search for outcomes that directly serve the needs of natural resource managers and decision-makers. Translational ecology is also distinct from knowledge co-production in that it does not require deep engagement between collaborators, although incorporating differing modes of co-production relative to the decision context, associated time frame, and available financial resources can greatly enhance the translational approach. Although there is a need for incentives to pursue in this type of work, we found that the creativity and context-specific knowledge of resource managers, practitioners, and decision-makers informs and enriches the scientific process, helping shape actionable science. Moreover, the process of addressing research questions arising from on-the-ground management issues, rather than from the top-down or expert-oriented perspectives of traditional science, can foster the long-term trust and commitment that is critical for long-term, sustained engagement between partners. Now, perhaps more than ever, the climate and environmental issues facing society are complex, often politicized, and value-laden. We argue that ecological science should play a key role in informing

The applicability of Lean and Six Sigma techniques to clinical and translational research.

Science.gov (United States)

Schweikhart, Sharon A; Dembe, Allard E

2009-10-01

Lean and Six Sigma are business management strategies commonly used in production industries to improve process efficiency and quality. During the past decade, these process improvement techniques increasingly have been applied outside the manufacturing sector, for example, in health care and in software development. This article concerns the potential use of Lean and Six Sigma in improving the processes involved in clinical and translational research. Improving quality, avoiding delays and errors, and speeding up the time to implementation of biomedical discoveries are prime objectives of the National Institutes of Health (NIH) Roadmap for Medical Research and the NIH's Clinical and Translational Science Award program. This article presents a description of the main principles, practices, and methods used in Lean and Six Sigma. Available literature involving applications of Lean and Six Sigma to health care, laboratory science, and clinical and translational research is reviewed. Specific issues concerning the use of these techniques in different phases of translational research are identified. Examples of Lean and Six Sigma applications that are being planned at a current Clinical and Translational Science Award site are provided, which could potentially be replicated elsewhere. We describe how different process improvement approaches are best adapted for particular translational research phases. Lean and Six Sigma process improvement methods are well suited to help achieve NIH's goal of making clinical and translational research more efficient and cost-effective, enhancing the quality of the research, and facilitating the successful adoption of biomedical research findings into practice.

Evidence-Based Scholarly Communication: Information Professionals Unlocking Translational Research

OpenAIRE

Philip J. Kroth; Holly E. Phillips; Jonathan D. Eldredge

2010-01-01

The Evidence-Based Scholarly Communication Conference (EBSCC) was held March 11-12, 2010 in Albuquerque, NM. The conference addressed the perceived gap in knowledge and training for scholarly communication principles in the National Institutes of Health (NIH) Clinical and Translational Science Award (CTSA) Program. The EBSCC brought together librarians and information specialists to share evidence based strategies for developing effective local scholarly communication support and training and...

Homi Bhabha Centre for Science Education, Tata Institute of ...

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 22; Issue 2. Homi Bhabha Centre for Science Education, Tata Institute of Fundamental Research (A Deemed University). Information and Announcements Volume 22 Issue 2 February 2017 pp 189-189 ...

The Natural Science Institute for Teachers of Minority Students: Performance report

Energy Technology Data Exchange (ETDEWEB)

Ervin, C.J.

1995-02-01

The purpose of the Natural Science Institute for Teachers of Minority Students is to enhance the science knowledge and skills of grades four through twelve science teachers in the District of Columbia Public Schools. The Institute brings school teachers together with practicing scientists and experienced science educators who are currently doing or involved in research and publication, especially in the area of global change. Special emphasis is placed on the interdisciplinary nature of science and the part played by the understanding and teaching about the dynamics of the environment and global change. In addition to these goals, teachers will learn a number of successful alternate strategies for teaching science to minority, disabled and non-English speaking students.

Hurdles in Basic Science Translation

Directory of Open Access Journals (Sweden)

Christina J. Perry

2017-07-01

Full Text Available In the past century there have been incredible advances in the field of medical research, but what hinders translation of this knowledge into effective treatment for human disease? There is an increasing focus on the failure of many research breakthroughs to be translated through the clinical trial process and into medical practice. In this mini review, we will consider some of the reasons that findings in basic medical research fail to become translated through clinical trials and into basic medical practices. We focus in particular on the way that human disease is modeled, the understanding we have of how our targets behave in vivo, and also some of the issues surrounding reproducibility of basic research findings. We will also look at some of the ways that have been proposed for overcoming these issues. It appears that there needs to be a cultural shift in the way we fund, publish and recognize quality control in scientific research. Although this is a daunting proposition, we hope that with increasing awareness and focus on research translation and the hurdles that impede it, the field of medical research will continue to inform and improve medical practice across the world.

[An introduction of the Translational Medical Science Committee (TMSC) of the Japanese Society of Neuropsychopharmacology].

Science.gov (United States)

Ishigooka, Jun

2014-06-01

The Japanese Society of Neuropsychopharmacology (NP) has established a Translational Medical Science Committee (TMSC), which is introduced in this article. In this century, the Japanese Government has made great effort to establish highly organized supporting systems for translational research (TR); however, clinical developments for psychotropic drugs in Japan are facing stagnation. TMSC will provide advisory activities from an academic point of view in this field, which will be result in the improvement of people's health.

76 FR 11500 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

Science.gov (United States)

2011-03-02

... Environmental Health Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory... Administrator, Nat. Institute of Environmental Health Sciences, Office of Program Operations, Scientific Review... . Name of Committee: National Institute of Environmental Health Sciences Special Emphasis Panel; Novel...

Policies, activities, and structures supporting research mentoring: a national survey of academic health centers with clinical and translational science awards.

Science.gov (United States)

Tillman, Robert E; Jang, Susan; Abedin, Zainab; Richards, Boyd F; Spaeth-Rublee, Brigitta; Pincus, Harold Alan

2013-01-01

To document the frequency of policies and activities in support of mentoring practices at institutions receiving a U.S. National Institutes of Health's Clinical and Translational Science Award (CTSA). The study consisted of a 69-item survey with questions about the inclusion (formal or informal) of policies, activities, and structures supporting mentoring within CTSA-sponsored research (i.e., KL2 programs) and, more broadly, in the CTSA's home institution. The survey, conducted from November 2010 through January 2011, was sent to the 55 institutions awarded CTSAs at the time of the survey. Follow-up phone interviews were conducted to clarify responses as needed. Fifty-one of 55 (92%) institutions completed the survey for institutional programs and 53 of 55 (96%) for KL2 programs. Responses regarding policies and activities involving mentor criteria, mentor-mentee relationship, incentives, and evaluative mechanisms revealed considerable variability between KL2 and institutional programs in some areas, such as having mentor qualification criteria and processes to evaluate mentors. The survey also identified areas, such as training and women and minority mentoring programs, where there was frequent sharing of activities between the institutional and KL2 programs. KL2 programs and institutional programs tend to have different preferences for policies versus activities to optimize qualification of mentors, the mentor-mentee relationship, incentives, and evaluation mechanisms. Frequently, these elements are informal. Individuals in charge of implementing and maintaining mentoring initiatives can use the results of the study to consider their current mentoring policies, structures, and activities by comparing them with national patterns within CTSA institutions.

Synthesizing Marketing, Community Engagement, and Systems Science Approaches for Advancing Translational Research.

Science.gov (United States)

Kneipp, Shawn M; Leeman, Jennifer; McCall, Pamela; Hassmiller-Lich, Kristen; Bobashev, Georgiy; Schwartz, Todd A; Gilmore, Robert; Riggan, Scott; Gil, Benjamin

2015-01-01

The adoption and implementation of evidence-based interventions (EBIs) are the goals of translational research; however, potential end-users' perceptions of an EBI value have contributed to low rates of adoption. In this article, we describe our application of emerging dissemination and implementation science theoretical perspectives, community engagement, and systems science principles to develop a novel EBI dissemination approach. Using consumer-driven, graphics-rich simulation, the approach demonstrates predicted implementation effects on health and employment outcomes for socioeconomically disadvantaged women at the local level and is designed to increase adoption interest of county program managers accountable for improving these outcomes in their communities.

NIH's National Institute of General Medical Sciences celebrates 45 years of Discovery for Health

Science.gov (United States)

... Alison Davis NIH's National Institute of General Medical Sciences celebrates 45 years of Discovery for Health The National Institute of General Medical Sciences (NIGMS) is the NIH institute that primarily supports ...

8th International Summer Institute in Surface Science

CERN Document Server

Howe, Russell

1988-01-01

This volume contains review articles written by the invited speakers at the eighth International Summer Institute in Surface Science (ISISS 1987), held at the University of Wisconsin-Milwaukee in August of 1987. During the course of ISISS, invited speakers, all internationally recognized experts in the various fields of surface science, present tutorial review lectures. In addition, these experts are asked to write review articles on their lecture topic. Former ISISS speakers serve as advisors concerning the selection of speakers and lecture topics. Em­ phasis is given to those areas which have not been covered in depth by recent Summer Institutes, as well as to areas which have recently gained in significance and in which important progress has been made. Because of space limitations, no individual volume of Chemistry and Physics of Solid Surfaces can possibly cover the whole area of modem surface science, or even give a complete survey of recent pro­ gress in the field. However, an attempt is made to pres...

78 FR 32259 - National Institute of Environmental Health Sciences; Amended Notice of Meeting

Science.gov (United States)

2013-05-29

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Environmental Health Sciences; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Institute of Environmental Health Sciences Special Emphasis Panel, July 15, 2013, 8:00 a...

Timelines of translational science: From technology initiation to FDA approval.

Directory of Open Access Journals (Sweden)

Laura M McNamee

Full Text Available While timelines for clinical development have been extensively studied, there is little data on the broader path from initiation of research on novel drug targets, to approval of drugs based on this research. We examined timelines of translational science for 138 drugs and biologicals approved by the FDA from 2010-2014 using an analytical model of technology maturation. Research on targets for 102 products exhibited a characteristic (S-curve maturation pattern with exponential growth between statistically defined technology initiation and established points. The median initiation was 1974, with a median of 25 years to the established point, 28 years to first clinical trials, and 36 years to FDA approval. No products were approved before the established point, and development timelines were significantly longer when the clinical trials began before this point (11.5 vs 8.5 years, p<0.0005. Technological maturation represents the longest stage of translation, and significantly impacts the efficiency of drug development.

Translational research in medicine

Directory of Open Access Journals (Sweden)

Bakir Mehić

2011-05-01

Full Text Available Translational medicine is a medical practice based on interventional epidemiology. It is regarded by its proponents as a natural progression from Evidence-Based Medicine. It integrates research from the basic sciences, social sciences and political sciences with the aim of optimizing patient care and preventive measures which may extend beyond healthcare services. In short, it is the process of turning appropriate biological discoveries into drugs and medical devices that can be used in the treatment of patients.[1]Scientific research and the development of modern powerful techniques are crucial for improving patient care in a society that is increasingly demanding the highest quality health services.[2] Indeed, effective patient care requires the continuous improvement of knowledge on the pathophysiology of the diseases, diagnostic procedures and therapeutic tools available. To this end, development of both clinical and basic research in health sciences is required. However, what is most effective in improving medical knowledge, and hence patient care, is the cross-fertilization between basic and clinical science. This has been specifically highlighted in recent years with the coining of the term “translational research”.[3] Translational research is of great importance in all medical specialties.Translational Research is the basis for Translational Medicine. It is the process which leads from evidence based medicine to sustainable solutions for public health problems.[4] It aims to improve the health and longevity of the world’s populations and depends on developing broad-based teams of scientists and scholars who are able to focus their efforts to link basic scientific discoveries with the arena of clinical investigation, and translating the results of clinical trials into changes in clinical practice, informed by evidence from the social and political sciences. Clinical science and ecological support from effective policies can�

77 FR 22793 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

Science.gov (United States)

2012-04-17

... Environmental Health Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory.... Institute of Environmental Health Sciences, P.O. Box 12233, MD EC-30, Research Triangle Park, NC 27709, (919....D., Scientific Review Administrator, Nat. Institute of Environmental Health Sciences, Office of...

77 FR 16844 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

Science.gov (United States)

2012-03-22

... Environmental Health Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory.... Institute Environmental Health Sciences, P.O. Box 12233, MD EC-30, Research Triangle Park, NC 27709, (919) 541-1307, [email protected] . Name of Committee: National Institute of Environmental Health Sciences...

Institute for Nuclear Research and Nuclear Energy and Nuclear Science

International Nuclear Information System (INIS)

Stamenov, J.

2004-01-01

The Institute for Nuclear Research and Nuclear Energy (INRNE) of the Bulgarian Academy of Sciences is the leading Bulgarian Institute for scientific investigations and applications of nuclear science. The main Institute's activities in the field of elementary particles and nuclear physics, high energy physics and nuclear energy, radiochemistry, radioecology, radioactive wastes treatment, monitoring of the environment, nuclear instruments development ect. are briefly described. Several examples for: environmental radiation monitoring; monitoring of the radioactivity and heavy metals in aerosols, 99m Tc clinical use, Boron Neutron Capture Therapy application of IRT-2000 Research Reactor, neutron fluence for reactor vessel embrittlement, NPP safety analysis, nuclear fuel modelling are also presented

78 FR 32672 - National Institute of Environmental Health Sciences (NIEHS); Notice of Meeting

Science.gov (United States)

2013-05-31

... Environmental Health Sciences (NIEHS); Notice of Meeting Pursuant to the NIH Reform Act of 2006 (42 U.S.C. 281 (d)(4)), notice is hereby given that the National Institute of Environmental Health Sciences (NIEHS... Popovich, National Institute of Environmental Health Sciences, Division of Extramural Research and Training...

77 FR 37423 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

Science.gov (United States)

2012-06-21

... Environmental Health Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory..., [email protected] . Name of Committee: National Institute of Environmental Health Sciences Special... Research and Training, Nat. Institute of Environmental Health Science, P.O. Box 12233, MD EC-30/Room 3170 B...

Translational Educational Research

Science.gov (United States)

Issenberg, S. Barry; Cohen, Elaine R.; Barsuk, Jeffrey H.; Wayne, Diane B.

2012-01-01

Medical education research contributes to translational science (TS) when its outcomes not only impact educational settings, but also downstream results, including better patient-care practices and improved patient outcomes. Simulation-based medical education (SBME) has demonstrated its role in achieving such distal results. Effective TS also encompasses implementation science, the science of health-care delivery. Educational, clinical, quality, and safety goals can only be achieved by thematic, sustained, and cumulative research programs, not isolated studies. Components of an SBME TS research program include motivated learners, curriculum grounded in evidence-based learning theory, educational resources, evaluation of downstream results, a productive research team, rigorous research methods, research resources, and health-care system acceptance and implementation. National research priorities are served from translational educational research. National funding priorities should endorse the contribution and value of translational education research. PMID:23138127

Making On-line Science Course Materials Easily Translatable and Accessible Worldwide: Challenges and Solutions

Science.gov (United States)

Adams, Wendy K.; Alhadlaq, Hisham; Malley, Christopher V.; Perkins, Katherine K.; Olson, Jonathan; Alshaya, Fahad; Alabdulkareem, Saleh; Wieman, Carl E.

2012-02-01

The PhET Interactive Simulations Project partnered with the Excellence Research Center of Science and Mathematics Education at King Saud University with the joint goal of making simulations useable worldwide. One of the main challenges of this partnership is to make PhET simulations and the website easily translatable into any language. The PhET project team overcame this challenge by creating the Translation Utility. This tool allows a person fluent in both English and another language to easily translate any of the PhET simulations and requires minimal computer expertise. In this paper we discuss the technical issues involved in this software solution, as well as the issues involved in obtaining accurate translations. We share our solutions to many of the unexpected problems we encountered that would apply generally to making on-line scientific course materials available in many different languages, including working with: languages written right-to-left, different character sets, and different conventions for expressing equations, variables, units and scientific notation.

76 FR 58521 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

Science.gov (United States)

2011-09-21

... Environmental Health Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory... and Training, Nat. Institute of Environmental Health Science, P. O. Box 12233, MD EC-30/Room 3170 B... Extramural Research and Training, Nat. Institute of Environmental Health Sciences, P. O. Box 12233, MD EC-30...

What can organisational theory offer knowledge translation in healthcare? A thematic and lexical analysis.

Science.gov (United States)

Dadich, Ann; Doloswala, Navin

2018-05-10

Despite the relative abundance of frameworks and models to guide implementation science, the explicit use of theory is limited. Bringing together two seemingly disparate fields of research, this article asks, what can organisational theory offer implementation science? This is examined by applying a theoretical lens that incorporates agency, institutional, and situated change theories to understand the implementation of healthcare knowledge into practice. Interviews were conducted with 20 general practitioners (GPs) before and after using a resource to facilitate evidence-based sexual healthcare. Research material was analysed using two approaches - researcher-driven thematic coding and lexical analysis, which was relatively less researcher-driven. The theoretical lens elucidated the complex pathways of knowledge translation. More specifically, agency theory revealed tensions between the GP as agent and their organisations and patients as principals. Institutional theory highlighted the importance of GP-embeddedness within their chosen specialty of general practice; their medical profession; and the practice in which they worked. Situated change theory exposed the role of localised adaptations over time - a metamorphosis. This study has theoretical, methodological, and practical implications. Theoretically, it is the first to examine knowledge translation using a lens premised on agency, institutional, and situated change theories. Methodologically, the study highlights the complementary value of researcher-driven and researcher-guided analysis of qualitative research material. Practically, this study signposts opportunities to facilitate knowledge translation - more specifically, it suggests that efforts to shape clinician practices should accommodate the interrelated influence of the agent and the institution, and recognise that change can be ever so subtle.

The ICNP BaT - from translation tool to translation web service.

Science.gov (United States)

Schrader, Ulrich

2009-01-01

The ICNP BaT has been developed as a web application to support the collaborative translation of different versions of the ICNP into different languages. A prototype of a web service is described that could reuse the translations in the database of the ICNP BaT to provide automatic translations of nursing content based on the ICNP terminology globally. The translation web service is based on a service-oriented architecture making it easy to interoperate with different applications. Such a global translation server would free individual institutions from the maintenance costs of realizing their own translation services.

Translational science by public biotechnology companies in the IPO "class of 2000": the impact of technological maturity.

Science.gov (United States)

McNamee, Laura; Ledley, Fred

2013-01-01

The biotechnology industry plays a central role in the translation of nascent biomedical science into both products that offer material health benefits and creating capital growth. This study examines the relationship between the maturity of technologies in a characteristic life cycle and value creation by biotechnology companies. We examined the core technology, product development pipelines, and capitalization for a cohort of biotechnology companies that completed an IPO in 2000. Each of these companies was well financed and had core technologies on the leading edge of biological science. We found that companies with the least mature technologies had significantly higher valuations at IPO, but failed to develop products based on these technologies over the ensuing decade, and created less capital growth than companies with more mature technologies at IPO. The observation that this cohort of recently public biotechnology companies was not effective in creating value from nascent science suggests the need for new, evidence-based business strategies for translational science.

76 FR 11765 - Education Research and Special Education Research Grant Programs; Institute of Education Sciences...

Science.gov (United States)

2011-03-03

... DEPARTMENT OF EDUCATION Education Research and Special Education Research Grant Programs; Institute of Education Sciences; Overview Information; Education Research and Special Education Research.... SUMMARY: The Director of the Institute of Education Sciences (Institute) announces the Institute's FY 2012...

University of Washington's eScience Institute Promotes New Training and Career Pathways in Data Science

Science.gov (United States)

Stone, S.; Parker, M. S.; Howe, B.; Lazowska, E.

2015-12-01

Rapid advances in technology are transforming nearly every field from "data-poor" to "data-rich." The ability to extract knowledge from this abundance of data is the cornerstone of 21st century discovery. At the University of Washington eScience Institute, our mission is to engage researchers across disciplines in developing and applying advanced computational methods and tools to real world problems in data-intensive discovery. Our research team consists of individuals with diverse backgrounds in domain sciences such as astronomy, oceanography and geology, with complementary expertise in advanced statistical and computational techniques such as data management, visualization, and machine learning. Two key elements are necessary to foster careers in data science: individuals with cross-disciplinary training in both method and domain sciences, and career paths emphasizing alternative metrics for advancement. We see persistent and deep-rooted challenges for the career paths of people whose skills, activities and work patterns don't fit neatly into the traditional roles and success metrics of academia. To address these challenges the eScience Institute has developed training programs and established new career opportunities for data-intensive research in academia. Our graduate students and post-docs have mentors in both a methodology and an application field. They also participate in coursework and tutorials to advance technical skill and foster community. Professional Data Scientist positions were created to support research independence while encouraging the development and adoption of domain-specific tools and techniques. The eScience Institute also supports the appointment of faculty who are innovators in developing and applying data science methodologies to advance their field of discovery. Our ultimate goal is to create a supportive environment for data science in academia and to establish global recognition for data-intensive discovery across all fields.

Local knowledge, science, and institutional change: the case of desertification control in Northern China.

Science.gov (United States)

Yang, Lihua

2015-03-01

This article studies the influence of local knowledge on the impact of science on institutional change in ecological and environmental management. Based on an empirical study on desertification control in 12 counties in north China, the study found the following major results: (1) although there was a cubic relationship between the extent and effect of local knowledge, local knowledge significantly influenced the impact of science on institutional change; (2) local knowledge took effect mainly through affecting formal laws and regulations, major actors, and methods of desertification control in institutional change but had no significant impact on the types of property rights; and (3) local knowledge enhanced the impact of science on the results of desertification control through affecting the impact of science on institutional change. These findings provide a reference for researchers, policy makers, and practitioners, both in China and in other regions of the world, to further explore the influence of local knowledge on the impact of science on institutional change and the roles of local knowledge or knowledge in institutional change and governance.

Annual report of national institute of radiological sciences

International Nuclear Information System (INIS)

1993-07-01

This annual report is a compilation of the research activities and achievement in the National Institute of Radiological Sciences (NIRS) in Japan during the fiscal year 1992 (from April 1992 through March 1993). Construction of the Heavy Ion Medical Accelerator in Chiba (HIMAC) has reached semi-final stage. The research covers a wide range of radiological sciences from molecular biology to environmental studies and medicine including engineering for heavy ion therapy of cancer. Topics consists of physics, chemistry, biomedical science, clinical research, and environmental sciences, covering a total of 84 titles. A list of publications by staff members, activities of research divisions, and organization chart of the NIRS are given in Appendix. (J.P.N.) 78 refs

Overview of the Inland California Translational Consortium

Science.gov (United States)

Malkas, Linda H.

2017-05-01

The mission of the Inland California Translational Consortium (ICTC), an independent research consortium comprising a unique hub of regional institutions (City of Hope [COH], California Institute of Technology [Caltech], Jet Propulsion Laboratory [JPL], University of California Riverside [UCR], and Claremont Colleges Keck Graduate Institute [KGI], is to institute a new paradigm within the academic culture to accelerate translation of innovative biomedical discoveries into clinical applications that positively affect human health and life. The ICTC actively supports clinical translational research as well as the implementation and advancement of novel education and training models for the translation of basic discoveries into workable products and practices that preserve and improve human health while training and educating at all levels of the workforce using innovative forward-thinking approaches.

Modeling timelines for translational science in cancer; the impact of technological maturation

OpenAIRE

McNamee, Laura M.; Ledley, Fred D.

2017-01-01

This work examines translational science in cancer based on theories of innovation that posit a relationship between the maturation of technologies and their capacity to generate successful products. We examined the growth of technologies associated with 138 anticancer drugs using an analytical model that identifies the point of initiation of exponential growth and the point at which growth slows as the technology becomes established. Approval of targeted and biological products corresponded ...

Inspiring hope-A physician's responsibility, translating the science into clinical practice.

Science.gov (United States)

Temple, Walley J

2018-03-01

Giving hope to patients is our responsibility. It is the essence of a meaningful practice in medicine. Science now allows us to understand this complex and multidimensional human dynamic, and translate it into clinical practice. Quantitative research has shown hope is strong even in terminal illness. Through qualitative methodology hope fostering strategies and hope hindering behaviors have been identified. This exciting new knowledge facilitates the challenging task of disclosure of bad news while enabling hope. © 2017 Wiley Periodicals, Inc.

Sociology, systems and (patient) safety: knowledge translations in healthcare policy.

Science.gov (United States)

Jensen, Casper Bruun

2008-03-01

In 2000 the American Institute of Medicine, adviser to the federal government on policy matters relating to the health of the public, published the report To Err is Human: Building a Safer Health System, which was to become a call to arms for improving patient safety across the Western world. By re-conceiving healthcare as a system, it was argued that it was possible to transform the current culture of blame, which made individuals take defensive precautions against being assigned responsibility for error - notably by not reporting adverse events, into a culture of safety. The IOM report draws on several prominent social scientists in accomplishing this re-conceptualisation. But the analyses of these authors are not immediately relevant for health policy. It requires knowledge translation to make them so. This paper analyses the process of translation. The discussion is especially pertinent due to a certain looping effect between social science research and policy concerns. The case here presented is thus doubly illustrative: exemplifying first how social science is translated into health policy and secondly how the transformation required for this to function is taken as an analytical improvement that can in turn be redeployed in social research.

Information actions in science and technology: institutionalities, agencies and subjects

Directory of Open Access Journals (Sweden)

Rodrigo Rabello

Full Text Available Considering the influence of new agency forms - intervention and interaction among subjects - in the context of information intermediation, we aim to approach information actions in Science and Technology (S&T taking into consideration the institutionalities involved. For such, we assume there is an influence of a theoretical model emerging in Information Science (IS regarding current inventive and interactive form propitiated by the Web. The text is structured in two central topics bringing: i theoretical and epistemic constructions of the "information action" concept; and ii a certain interpretation oriented by the "informational action in S&T" construct, taking as its object the actions performed by IBICT (Brazilian Institute for Information in Science and Technology, directed towards excellence in information. Finally, we discuss how limitations of the "systemic model" propitiate the construction of new study objects in the model emerging in IS from theoretical innovations and counterpoints thoughts facing the diverse forms of information action, considering, for instance, the action of subjects on what concerns the validation of information in the current scenery of institutional intermediation.

Activities of the Institute for Computer Applications in Science and Engineering

Science.gov (United States)

1985-01-01

Research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics, numerical analysis, and computer science during the period April 1, 1985 through October 2, 1985 is summarized.

The impact of institutional ethics on academic health sciences library leadership: a survey of academic health sciences library directors.

Science.gov (United States)

Tooey, Mary Joan M J; Arnold, Gretchen N

2014-10-01

Ethical behavior in libraries goes beyond service to users. Academic health sciences library directors may need to adhere to the ethical guidelines and rules of their institutions. Does the unique environment of an academic health center imply different ethical considerations? Do the ethical policies of institutions affect these library leaders? Do their personal ethical considerations have an impact as well? In December 2013, a survey regarding the impact of institutional ethics was sent to the director members of the Association of Academic Health Sciences Libraries. The objective was to determine the impact of institutional ethics on these leaders, whether through personal conviction or institutional imperative.

A Matrix Mentoring Model That Effectively Supports Clinical and Translational Scientists and Increases Inclusion in Biomedical Research: Lessons From the University of Utah.

Science.gov (United States)

Byington, Carrie L; Keenan, Heather; Phillips, John D; Childs, Rebecca; Wachs, Erin; Berzins, Mary Anne; Clark, Kim; Torres, Maria K; Abramson, Jan; Lee, Vivian; Clark, Edward B

2016-04-01

Physician-scientists and scientists in all the health professions are vital members of the U.S. biomedical workforce, but their numbers at academic health centers are declining. Mentorship has been identified as a key component in retention of faculty members at academic health centers. Effective mentoring may promote the retention of clinician-scientists in the biomedical workforce. The authors describe a holistic institutional mentoring program to support junior faculty members engaged in clinical and translational science at the University of Utah. The clinical and translational scholars (CATS) program leverages the resources of the institution, including the Center for Clinical and Translational Science, to augment departmental resources to support junior faculty investigators and uses a multilevel mentoring matrix that includes self, senior, scientific, peer, and staff mentorship. Begun in the Department of Pediatrics, the program was expanded in 2013 to include all departments in the school of medicine and the health sciences. During the two-year program, scholars learn management essentials and have leadership training designed to develop principal investigators. Of the 86 program participants since fiscal year 2008, 92% have received extramural awards, 99% remain in academic medicine, and 95% remain at the University of Utah. The CATS program has also been associated with increased inclusion of women and underrepresented minorities in the institutional research enterprise. The CATS program manifests institutional collaboration and coordination of resources, which have benefited faculty members and the institution. The model can be applied to other academic health centers to support and sustain the biomedical workforce.

Modeling timelines for translational science in cancer; the impact of technological maturation.

Directory of Open Access Journals (Sweden)

Laura M McNamee

Full Text Available This work examines translational science in cancer based on theories of innovation that posit a relationship between the maturation of technologies and their capacity to generate successful products. We examined the growth of technologies associated with 138 anticancer drugs using an analytical model that identifies the point of initiation of exponential growth and the point at which growth slows as the technology becomes established. Approval of targeted and biological products corresponded with technological maturation, with first approval averaging 14 years after the established point and 44 years after initiation of associated technologies. The lag in cancer drug approvals after the increases in cancer funding and dramatic scientific advances of the 1970s thus reflects predictable timelines of technology maturation. Analytical models of technological maturation may be used for technological forecasting to guide more efficient translation of scientific discoveries into cures.

Translating Alcohol Research

Science.gov (United States)

Batman, Angela M.; Miles, Michael F.

2015-01-01

Alcohol use disorder (AUD) and its sequelae impose a major burden on the public health of the United States, and adequate long-term control of this disorder has not been achieved. Molecular and behavioral basic science research findings are providing the groundwork for understanding the mechanisms underlying AUD and have identified multiple candidate targets for ongoing clinical trials. However, the translation of basic research or clinical findings into improved therapeutic approaches for AUD must become more efficient. Translational research is a multistage process of streamlining the movement of basic biomedical research findings into clinical research and then to the clinical target populations. This process demands efficient bidirectional communication across basic, applied, and clinical science as well as with clinical practitioners. Ongoing work suggests rapid progress is being made with an evolving translational framework within the alcohol research field. This is helped by multiple interdisciplinary collaborative research structures that have been developed to advance translational work on AUD. Moreover, the integration of systems biology approaches with collaborative clinical studies may yield novel insights for future translational success. Finally, appreciation of genetic variation in pharmacological or behavioral treatment responses and optimal communication from bench to bedside and back may strengthen the success of translational research applications to AUD. PMID:26259085

Networking of institutions in India to promote research and education in nuclear science and engineering

International Nuclear Information System (INIS)

Puri, R.R.

2007-01-01

will pool together the strength of each of its CI to accelerate the pace of basic research and its translation in to technology development. It would provide unique opportunity to students to learn from, and work with people having hands-on experience in the environment of highly advanced research facilities hardly available elsewhere in the country. It would promote interdisciplinary research essential for development of nuclear science and technology. The setting-up of HBNI is expected to attract those talented youngsters to nuclear science and engineering who are looking for intellectual challenges and recognition of their efforts in terms of formal degrees. The networking of the DAE Institutes under the umbrella of HBNI is a unique experiment to promote research and education in nuclear science and engineering in India. In the years to come, admission to HBNI may be opened to students from other countries. (author)

Expanding the knowledge translation metaphor.

Science.gov (United States)

Engebretsen, Eivind; Sandset, Tony Joakim; Ødemark, John

2017-03-13

Knowledge translation (KT) is a buzzword in modern medical science. However, there has been little theoretical reflection on translation as a process of meaning production in KT. In this paper, we argue that KT will benefit from the incorporation of a more theoretical notion of translation as an entangled material, textual and cultural process. We discuss and challenge fundamental assumptions in KT, drawing on theories of translation from the human sciences. We show that the current construal of KT as separate from and secondary to the original scientific message is close to the now deeply compromised literary view of translation as the simple act of copying the original. Inspired by recent theories of translation, we claim that KT can be more adequately understood in terms of a 'double supplement' - on the one hand, KT offers new approaches to the communication of scientific knowledge to different groups in the healthcare system with the aim of supplementing a lack of knowledge among clinicians (and patients). On the other, it demonstrates that a textual and cultural supplement, namely a concern with target audiences (clinicians and patients), is inevitable in the creation of an 'autonomous' science. Hence, the division between science and its translation is unproductive and impossible to maintain. We discuss some possible implications of our suggested shift in concept by drawing on pharmaceutical interventions for the prevention of HIV as a case. We argue that such interventions are based on a supplementary and paradoxical relation to the target audiences, both presupposing and denying their existence. More sophisticated theories of translation can lay the foundation for an expanded model of KT that incorporates a more adequate and reflective description of the interdependency of scientific, cultural, textual and material practices.

Pioneering the Transdisciplinary Team Science Approach: Lessons Learned from National Cancer Institute Grantees.

Science.gov (United States)

Vogel, Amanda L; Stipelman, Brooke A; Hall, Kara L; Nebeling, Linda; Stokols, Daniel; Spruijt-Metz, Donna

2014-01-01

The National Cancer Institute has been a leader in supporting transdisciplinary (TD) team science. From 2005-2010, the NCI supported Transdisciplinary Research on Energetic and Cancer I (TREC I), a center initiative fostering the TD integration of social, behavioral, and biological sciences to examine the relationships among obesity, nutrition, physical activity and cancer. In the final year of TREC I, we conducted qualitative in-depth-interviews with 31 participating investigators and trainees to learn more about their experiences with TD team science, including challenges, facilitating factors, strategies for success, and impacts. Five main challenges emerged: (1) limited published guidance for how to engage in TD team science, when TREC I was implemented; (2) conceptual and scientific challenges inherent to efforts to achieve TD integration; (3) discipline-based differences in values, terminology, methods, and work styles; (4) project management challenges involved in TD team science; and (5) traditional incentive and reward systems that do not recognize or reward TD team science. Four main facilitating factors and strategies for success emerged: (1) beneficial attitudes and beliefs about TD research and team science; (2) effective team processes; (3) brokering and bridge-building activities by individuals holding particular roles in a research center; and (4) funding initiative characteristics that support TD team science. Broad impacts of participating in TD team science in the context of TREC I included: (1) new positive attitudes about TD research and team science; (2) new boundary-crossing collaborations; (3) scientific advances related to research approaches, findings, and dissemination; (4) institutional culture change and resource creation in support of TD team science; and (5) career advancement. Funding agencies, academic institutions, and scholarly journals can help to foster TD team science through funding opportunities, institutional policies on

D1-3: Marshfield Dictionary of Clinical and Translational Science (MD-CTS): An Online Reference for Clinical and Translational Science Terminology

Science.gov (United States)

Finamore, Joe; Ray, William; Kadolph, Chris; Rastegar-Mojarad, Majid; Ye, Zhan; Jacqueline, Bohne; Tachinardi, Umberto; Mendonça, Eneida; Finnegan, Brian; Bartkowiak, Barbara; Weichelt, Bryan; Lin, Simon

2014-01-01

Background/Aims New terms are rapidly appearing in the literature and practice of clinical medicine and translational research. To catalog real-world usage of medical terms, we report the first construction of an online dictionary of clinical and translational medicinal terms, which are computationally generated in near real-time using a big data approach. This project is NIH CTSA-funded and developed by the Marshfield Clinic Research Foundation in conjunction with University of Wisconsin - Madison. Currently titled Marshfield Dictionary of Clinical and Translational Science (MD-CTS), this application is a Google-like word search tool. By entering a term into the search bar, MD-CTS will display that term’s definition, usage examples, contextual terms, related images, and ontological information. A prototype is available for public viewing at http://spellchecker.mfldclin.edu/. Methods We programmatically derived the lexicon for MD-CTS from scholarly communications by parsing through 15,156,745 MEDLINE abstracts and extracting all of the unique words found therein. We then ran this list through several filters in order to remove words that were not relevant for searching, such as common English words and numeric expressions. We then loaded the resulting 1,795,769 terms into SQL tables. Each term is cross-referenced with every occurrence in all abstracts in which it was found. Additional information is aggregated from Wiktionary, Bioportal, and Wikipedia in real-time and displayed on-screen. From this lexicon we created a supplemental dictionary resource (updated quarterly) to be used in Microsoft Office® products. Results We evaluated the utility of MD-CTS by creating a list of 100 words derived from recent clinical and translational medicine publications in the week of July 22, 2013. We then performed comparative searches for each term with Taber’s Cyclopedic Medical Dictionary, Stedman’s Medical Dictionary, Dorland’s Illustrated Medical Dictionary, Medical

Translational Geoscience: Converting Geoscience Innovation into Societal Impacts

Science.gov (United States)

Schiffries, C. M.

2015-12-01

Translational geoscience — which involves the conversion of geoscience discovery into societal, economic, and environmental impacts — has significant potential to generate large benefits but has received little systematic attention or resources. In contrast, translational medicine — which focuses on the conversion of scientific discovery into health improvement — has grown enormously in the past decade and provides useful models for other fields. Elias Zerhouni [1] developed a "new vision" for translational science to "ensure that extraordinary scientific advances of the past decade will be rapidly captured, translated, and disseminated for the benefit of all Americans." According to Francis Collins, "Opportunities to advance the discipline of translational science have never been better. We must move forward now. Science and society cannot afford to do otherwise." On 9 July 2015, the White House issued a memorandum directing U.S. federal agencies to focus on translating research into broader impacts, including commercial products and decision-making frameworks [3]. Natural hazards mitigation is one of many geoscience topics that would benefit from advances in translational science. This paper demonstrates that natural hazards mitigation can benefit from advances in translational science that address such topics as improving emergency preparedness, communicating life-saving information to government officials and citizens, explaining false positives and false negatives, working with multiple stakeholders and organizations across all sectors of the economy and all levels of government, and collaborating across a broad range of disciplines. [1] Zerhouni, EA (2005) New England Journal of Medicine 353(15):1621-1623. [2] Collins, FS (2011) Science Translational Medicine 3(90):1-6. [3] Donovan, S and Holdren, JP (2015) Multi-agency science and technology priorities for the FY 2017 budget. Executive Office of the President of the United States, 5 pp.

Environmental Aspects of Tritium Around the Vinca Institute of Nuclear Sciences

International Nuclear Information System (INIS)

Miljevic, N.; Sipka, V.

1995-01-01

An overview of environmental distribution of tritium around the Institute of Nuclear Sciences Vinca during the period 1988-1994 is presented. Temporal and local variations of the specific tritium variations in precipitation (Usek, Zeleno Brdo), river waters (the Danube, the Sava and Mlaka Creek) as well as atmospheric water vapor are given. Estimates based on precipitation measurements have shown that 6.3 TBq of tritium activity should be released annually into the atmosphere from the Vinca Institute of Nuclear Sciences. (author)

78 FR 47715 - National Institute of Environmental Health Sciences; Amended Notice of Meeting

Science.gov (United States)

2013-08-06

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Environmental Health Sciences; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the Environmental Health Sciences Review Committee, July 24, 2013, 08:00 a.m. to July 26, 2013, 02:00...

Annual report of National Institute of Radiological Science, April 1995 -March 1996

International Nuclear Information System (INIS)

1997-03-01

This annual report presents a brief summary of the research activities and the achievements in the Institute for fiscal year 1995 (from April 1995 to March 1996). The clinical trial of cancer therapy using heavy ion beams is making progress with successful results. Various kinds of basic researches using the same heavy ion beams are also growing up gradually in an open use system available to many researchers not only inside but also outside the Institute. Studies of newly assembled research groups are also going to appear. The Institute is covering a very wide area of comprehensive radiological sciences including physics, chemistry, biomedical sciences, clinical research and environmental science. The recent publications, list of keywords, author index, and organization and staff are included in this report. (M.N.)

Annual report of National Institute of Radiological Science, April 1995 - March 1996

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-03-01

This annual report presents a brief summary of the research activities and the achievements in the Institute for fiscal year 1995 (from April 1995 to March 1996). The clinical trial of cancer therapy using heavy ion beams is making progress with successful results. Various kinds of basic researches using the same heavy ion beams are also growing up gradually in an open use system available to many researchers not only inside but also outside the Institute. Studies of newly assembled research groups are also going to appear. The Institute is covering a very wide area of comprehensive radiological sciences including physics, chemistry, biomedical sciences, clinical research and environmental science. The recent publications, list of keywords, author index, and organization and staff are included in this report. (M.N.)

e-Science platform for translational biomedical imaging research: running, statistics, and analysis

Science.gov (United States)

Wang, Tusheng; Yang, Yuanyuan; Zhang, Kai; Wang, Mingqing; Zhao, Jun; Xu, Lisa; Zhang, Jianguo

2015-03-01

In order to enable multiple disciplines of medical researchers, clinical physicians and biomedical engineers working together in a secured, efficient, and transparent cooperative environment, we had designed an e-Science platform for biomedical imaging research and application cross multiple academic institutions and hospitals in Shanghai and presented this work in SPIE Medical Imaging conference held in San Diego in 2012. In past the two-years, we implemented a biomedical image chain including communication, storage, cooperation and computing based on this e-Science platform. In this presentation, we presented the operating status of this system in supporting biomedical imaging research, analyzed and discussed results of this system in supporting multi-disciplines collaboration cross-multiple institutions.

Developing institutional repository at National Institute for Materials Science : Researchers directory service “SAMURAI” and Research Collection Library

Science.gov (United States)

Takaku, Masao; Tanifuji, Mikiko

National Institute for Materials Science (NIMS) has developed an institutional repository “NIMS eSciDoc” since 2008. eSciDoc is an open source repository software made in Germany, and provides E-Science infrastructures through its flexible data model and rich Web APIs. NIMS eScidoc makes use of eSciDoc functions to benefit for NIMS situations. This article also focuses on researchers directory service “SAMURAI” in addition to NIMS eSciDoc. Successfully launched in October 2010, SAMURAI provides approximately 500 researchers' profile and publication information.

76 FR 50235 - National Institute of Environmental Health Sciences; Notice of Meetings

Science.gov (United States)

2011-08-12

... Environmental Health Sciences; Notice of Meetings Pursuant to section 10(a) of the Federal Advisory Committee... (DERT), Nat. Inst. of Environmental Health Sciences, National Institutes of Health, 615 Davis Dr... of Extramural Research and Training (DERT), Nat. Inst. of Environmental Health Sciences, National...

La fabrique des sciences des institutions aux pratiques

CERN Document Server

Benninghoff, Martin; Crettaz von Roten, Fabienne; Merz, Martina

2006-01-01

Aujourd'hui, les façons de produire, d'organiser, d'évaluer et d'utiliser les savoirs sont en profond débat. De plus en plus, l'Etat, la société civile et l'économie tentent d'influencer les activités des universités et des laboratoires de recherche. Ces développements mettent à l'épreuve tout à la fois les fondements des systèmes d'enseignement supérieur et de recherche, l'autonomie des institutions scientifiques, la définition des frontières des savoirs et l'acceptation des sciences. Dans des contextes suisses et européens, cet ouvrage s'intéresse aux manières dont les sciences et les technologies sont fabriquées, en analysant leurs institutions et les pratiques. A partir d'une approche relationnelle, les sciences et les technologies sont conçues comme des phénomènes profondément sociaux, culturels et politiques. Une telle démarche déstabilise les visions parfois idéalisées et stéréotypées de la construction des savoirs. Des études de cas détaillées décrivent des phénomè...

76 FR 7572 - National Institute of Environmental Health Sciences; Notice of Meetings

Science.gov (United States)

2011-02-10

... Environmental Health Sciences; Notice of Meetings Pursuant to section 10(a) of the Federal Advisory Committee..., Director, Division of Extramural Research and Training, National Institute of Environmental Health Sciences... of Environmental Health Sciences, 615 Davis Dr., KEY615/3112, Research Triangle Park, NC 27709, (919...

76 FR 77239 - National Institute of Environmental Health Sciences; Notice of Meeting

Science.gov (United States)

2011-12-12

... Environmental Health Sciences; Notice of Meeting Pursuant to section 10(a) of the Federal Advisory Committee Act.../boards/ibcercc/ . Place: National Institute of Environmental Health Sciences, Building 101, Rodbell... and Education; 93.894, Resources and Manpower Development in the Environmental Health Sciences; 93.113...

77 FR 66853 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

Science.gov (United States)

2012-11-07

... Environmental Health Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory... Health Sciences Special Emphasis Panel Career Grants in the Environmental Health Sciences. Date: November...., Scientific Review Administrator, Nat. Institute of Environmental Health Sciences, Office of Program...

76 FR 80954 - National Institute of Environmental Health Sciences; Notice of Meeting

Science.gov (United States)

2011-12-27

... Environmental Health Sciences; Notice of Meeting Pursuant to section 10(a) of the Federal Advisory Committee Act.../boards/ibcercc/ . Place: Nat. Inst. of Environmental Health Sciences, Building 101, Rodbell Auditorium... Environmental Health Sciences, National Institutes of Health, 615 Davis Dr., KEY615/3112, Research Triangle Park...

77 FR 39688 - Notice of Proposed Information Collection Requests; Institute of Education Sciences; FAFSA...

Science.gov (United States)

2012-07-05

... DEPARTMENT OF EDUCATION Notice of Proposed Information Collection Requests; Institute of Education Sciences; FAFSA Completion Project Evaluation SUMMARY: The Institute of Education Sciences (IES) at the U.S. Department of Education (ED) is conducting a rigorous study of the Free Application for Federal Student Aid...

Science for Society Workshop Summary Report

Energy Technology Data Exchange (ETDEWEB)

Wolfe, Amy K [ORNL; Bjornstad, David J [ORNL; Lenhardt, W Christopher [ORNL; Shumpert, Barry L [ORNL; Wang, Stephanie [ORNL

2012-02-01

science mission and the translation of that science for use; and (3) ORNL should design its commitments and actions for helping move science from the Laboratory toward use to align with one another and should integrate them into its institutional culture in such a way as to elevate research translation and application to coequal status with scientific excellence. Participants made several actionable recommendations for enhancing research translation at ORNL, some of which were particular to specific S and T domains. Among the recommendations that participants agreed apply Lab-wide are to: align metrics and incentives with research translation goals; manage risks and conflicts of interest instead of avoiding them; and create programs (e.g., entrepreneurial leave) that promote interactions between key ORNL staff and industry in ways that complement careers at ORNL.

76 FR 13197 - National Institute of Environmental Health Sciences Strategic Planning

Science.gov (United States)

2011-03-10

... parties. The goal of this strategic planning process is to define an overarching Vision Statement... this planning process, visit the NIEHS Strategic Planning Web site at Request for Visionary Ideas The... Environmental Health Sciences Strategic Planning AGENCY: National Institutes of Health (NIH), National Institute...

Activities of the Institute for Computer Applications in Science and Engineering (ICASE)

Science.gov (United States)

1988-01-01

This report summarizes research conducted at the Institute for Computer Applications Science and Engineering in applied mathematics, numerical analysis, and computer science during the period October 2, 1987 through March 31, 1988.

[Research Conducted at the Institute for Computer Applications in Science and Engineering

Science.gov (United States)

1997-01-01

This report summarizes research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics, fluid mechanics, and computer science during the period 1 Oct. 1996 - 31 Mar. 1997.

Annual report of the National Institute of Radiological Sciences. April 2000-March 2001

International Nuclear Information System (INIS)

2001-10-01

This report contains all of accomplishments of National Institute of Radiological Sciences (NIRS), including research and investigations, medical practice, training and technology assistance the institute performed during the given year. Actually, the content covers NIRS activity results in the fields of physics (6 presentations), chemistry (3), bio-medical sciences, clinical research (7), environmental science (15) and space science (5). The third involves fields of biochemistry and biophysics (6), cell biology (6), immunology and hematology (1), pathology and physiology (5), genetics (8) and radiotoxicology (1). Topical issues are clinical trials of heavy-ion radiotherapy for cancer; researches of radiation-sensitive genes and gene-expression profiles; and activities for various accidents after the turning point of the JCO criticality accident in Tokai. NIRS was reborn as an independent corporative body as a result of the national administrative reform and this report is the final one as that from the national institute. (N.I.)

A GRAMMATICAL ADJUSTMENT ANALYSIS OF STATISTICAL MACHINE TRANSLATION METHOD USED BY GOOGLE TRANSLATE COMPARED TO HUMAN TRANSLATION IN TRANSLATING ENGLISH TEXT TO INDONESIAN

Directory of Open Access Journals (Sweden)

Eko Pujianto

2017-04-01

Full Text Available Google translate is a program which provides fast, free and effortless translating service. This service uses a unique method to translate. The system is called ―Statistical Machine Translation‖, the newest method in automatic translation. Machine translation (MT is an area of many kinds of different subjects of study and technique from linguistics, computers science, artificial intelligent (AI, translation theory, and statistics. SMT works by using statistical methods and mathematics to process the training data. The training data is corpus-based. It is a compilation of sentences and words of the languages (SL and TL from translation done by human. By using this method, Google let their machine discovers the rules for themselves. They do this by analyzing millions of documents that have already been translated by human translators and then generate the result based on the corpus/training data. However, questions arise when the results of the automatic translation prove to be unreliable in some extent. This paper questions the dependability of Google translate in comparison with grammatical adjustment that naturally characterizes human translators' specific advantage. The attempt is manifested through the analysis of the TL of some texts translated by the SMT. It is expected that by using the sample of TL produced by SMT we can learn the potential flaws of the translation. If such exists, the partial of more substantial undependability of SMT may open more windows to the debates of whether this service may suffice the users‘ need.

Technological Devices Improving System of Translating Languages: What About their Usefulness on the Applicability in Medicine and Health Sciences?

Directory of Open Access Journals (Sweden)

Adilia Maria Pires Sciarra

2015-12-01

Full Text Available ABSTRACT INTRODUCTION: In a world in which global communication is becoming ever more important and in which English is increasingly positioned as the pre-eminent international language, that is, English as a Lingua Franca refers to the use of English as a medium of communication between peoples of different languages. It is important to highlight the positive advances in communication in health, provided by technology. OBJECTIVE: To present an overview on some technological devices of translating languages provided by the Web as well as to point out some advantages and disadvantages specially using Google Translate in Medicine and Health Sciences. METHODS: A bibliographical survey was performed to provide an overview on the usefulness of online translators for applicability using written and spoken languages. RESULTS: As we have to consider this question to be further surely answered, this study could present some advantages and disadvantages in using translating online devices. CONCLUSION: Considering Medicine and Health Sciences as expressive into the human scientific knowledge to be spread worldwidely; technological devices available on communication should be used to overcome some language barriers either written or spoken, but with some caution depending on the context of their applicability.

Technological Devices Improving System of Translating Languages: What About their Usefulness on the Applicability in Medicine and Health Sciences?

Science.gov (United States)

Sciarra, Adilia Maria Pires; Batigália, Fernando; Oliveira, Marcos Aurélio Barboza de

2015-01-01

In a world in which global communication is becoming ever more important and in which English is increasingly positioned as the pre-eminent international language, that is, English as a Lingua Franca refers to the use of English as a medium of communication between peoples of different languages. It is important to highlight the positive advances in communication in health, provided by technology. To present an overview on some technological devices of translating languages provided by the Web as well as to point out some advantages and disadvantages specially using Google Translate in Medicine and Health Sciences. A bibliographical survey was performed to provide an overview on the usefulness of online translators for applicability using written and spoken languages. As we have to consider this question to be further surely answered, this study could present some advantages and disadvantages in using translating online devices. Considering Medicine and Health Sciences as expressive into the human scientific knowledge to be spread worldwidely; technological devices available on communication should be used to overcome some language barriers either written or spoken, but with some caution depending on the context of their applicability.

76 FR 71046 - National Institute of Environmental Health Sciences; Notice of Meeting

Science.gov (United States)

2011-11-16

... Environmental Health Sciences; Notice of Meeting Pursuant to section 10(a) of the Federal Advisory Committee Act... Environmental Health Sciences, National Institutes of Health, 615 Davis Dr., KEY615/3112, Research Triangle Park... and Education; 93.894, Resources and Manpower Development in the Environmental Health Sciences; 93.113...

Translational genomics

Directory of Open Access Journals (Sweden)

Martin Kussmann

2014-09-01

Full Text Available The term “Translational Genomics” reflects both title and mission of this new journal. “Translational” has traditionally been understood as “applied research” or “development”, different from or even opposed to “basic research”. Recent scientific and societal developments have triggered a re-assessment of the connotation that “translational” and “basic” are either/or activities: translational research nowadays aims at feeding the best science into applications and solutions for human society. We therefore argue here basic science to be challenged and leveraged for its relevance to human health and societal benefits. This more recent approach and attitude are catalyzed by four trends or developments: evidence-based solutions; large-scale, high dimensional data; consumer/patient empowerment; and systems-level understanding.

NASA's Solar System Exploration Research Virtual Institute: Science and Technology for Lunar Exploration

Science.gov (United States)

Schmidt, Greg; Bailey, Brad; Gibbs, Kristina

2015-01-01

The NASA Solar System Exploration Research Virtual Institute (SSERVI) is a virtual institute focused on research at the intersection of science and exploration, training the next generation of lunar scientists, and development and support of the international community. As part of its mission, SSERVI acts as a hub for opportunities that engage the larger scientific and exploration communities in order to form new interdisciplinary, research-focused collaborations. The nine domestic SSERVI teams that comprise the U.S. complement of the Institute engage with the international science and exploration communities through workshops, conferences, online seminars and classes, student exchange programs and internships. SSERVI represents a close collaboration between science, technology and exploration enabling a deeper, integrated understanding of the Moon and other airless bodies as human exploration moves beyond low Earth orbit. SSERVI centers on the scientific aspects of exploration as they pertain to the Moon, Near Earth Asteroids (NEAs) and the moons of Mars, with additional aspects of related technology development, including a major focus on human exploration-enabling efforts such as resolving Strategic Knowledge Gaps (SKGs). The Institute focuses on interdisciplinary, exploration-related science focused on airless bodies targeted as potential human destinations. Areas of study represent the broad spectrum of lunar, NEA, and Martian moon sciences encompassing investigations of the surface, interior, exosphere, and near-space environments as well as science uniquely enabled from these bodies. This research profile integrates investigations of plasma physics, geology/geochemistry, technology integration, solar system origins/evolution, regolith geotechnical properties, analogues, volatiles, ISRU and exploration potential of the target bodies. New opportunities for both domestic and international partnerships are continually generated through these research and

Translation, Cultural Translation and the Hegemonic English

Directory of Open Access Journals (Sweden)

Roman Horak

2015-01-01

Full Text Available This brief chapter problematizes the hegemonic position of the English language in Cultural Studies, which, in the author's view, can be understood as a moment that stands against a true internationalisation of the project. Following an argu-ment referring to the necessary 'translation' process (here seen as 're-articulation', 'transcoding' or 'transculturation' Stuart Hall has put forward almost two decades ago, the essay, firstly, turns to the notion of 'linguistic translations', and deals, secondly, with what has been coined 'cultural translation'. Discussing approaches developed by Walter Benjamin, Umberto Eco and Homi Bhabha, the complex relationship between the two terms is being investigated. Finally, in a modest attempt to throw some light on this hegemonic structure, central aspects of the output of three important journals (European Journal of Cultural Studies, International Journal of Cultural Studies, Cultural Studies, i. e. an analysis of the linguistic and institutional backgrounds of the authors of the ten most-read and most-cited essays, are presented. Based on these findings I argue that it is not simply the addition of the discursive field (language to the academic space (institution that defines the mecha-nism of exclusion and inclusion. Rather, it is the articulation of both moments, i.e. that of language and that of the institution, which - in various contexts (but in their own very definite ways - can help to develop that structure which at present is still hindering a further, more profound internationalisation of the project that is Cultural Studies.

Exploring How Second Grade Elementary Teachers Translate Their Nature of Science Views into Classroom Practice After a Graduate Level Nature of Science Course

Science.gov (United States)

Deniz, Hasan; Adibelli, Elif

2015-12-01

The main purpose of this study was to explore the factors mediating the translation of second grade teachers' nature of science (NOS) views into classroom practice after completing a graduate level NOS course. Four second grade in-service elementary teachers comprised the sample of this study. Data were collected from several sources during the course of this study. The primary data sources were (a) assessment of the elementary teachers' NOS views before and after the graduate level NOS course using the Views of Nature of Science Questionnaire Version B (VNOS-B) (Lederman et al., 2002) coupled with interviews, and (b) a classroom observation and videotaped recording of the elementary teachers' best NOS lessons coupled with interview. We identified three distinct but related factors that mediated the translation of NOS views into classroom practice: the teachers' perspectives about the developmental appropriateness of the NOS aspect, the teachers' selection of target NOS aspects, and the relative importance placed by teachers on each NOS aspect.

Translational plant proteomics: a perspective.

Science.gov (United States)

Agrawal, Ganesh Kumar; Pedreschi, Romina; Barkla, Bronwyn J; Bindschedler, Laurence Veronique; Cramer, Rainer; Sarkar, Abhijit; Renaut, Jenny; Job, Dominique; Rakwal, Randeep

2012-08-03

Translational proteomics is an emerging sub-discipline of the proteomics field in the biological sciences. Translational plant proteomics aims to integrate knowledge from basic sciences to translate it into field applications to solve issues related but not limited to the recreational and economic values of plants, food security and safety, and energy sustainability. In this review, we highlight the substantial progress reached in plant proteomics during the past decade which has paved the way for translational plant proteomics. Increasing proteomics knowledge in plants is not limited to model and non-model plants, proteogenomics, crop improvement, and food analysis, safety, and nutrition but to many more potential applications. Given the wealth of information generated and to some extent applied, there is the need for more efficient and broader channels to freely disseminate the information to the scientific community. This article is part of a Special Issue entitled: Translational Proteomics. Copyright © 2012 Elsevier B.V. All rights reserved.

Translational neural engineering: multiple perspectives on bringing benchtop research into the clinical domain.

Science.gov (United States)

Rousche, Patrick; Schneeweis, David M; Perreault, Eric J; Jensen, Winnie

2008-03-01

strongly encouraged open industrial-academic partnerships as an efficient path forward in the translational process. Joe Pancrazio, PhD, a Program Director at NIH's National Institute of Neurological Disorders and Stroke, emphasized that NIH funding for translational research was aimed at breaking down scientific barriers to clinic entrance. Vivian Weil, PhD, (Director of Center for the Study of Ethics in the Professions at the Illinois Institute of Technology) a specialist on ethics in science and engineering, spoke of the usefulness of developing a code of ethics for addressing ethical aspects of translation from the bench to clinical implementation and of translation across disciplines in multi-disciplinary projects. Finally, the patient perspective was represented by Mr Jesse Sullivan. A double-arm amputee and patient of Dr Kuiken's, Mr Sullivan demonstrated the critically important role of the patient in successful translational neural engineering research.

LATIN AND SCIENCE: PERSPECTIVES ON TRANSLATION OF THE NEO-LATIN ON SCIENCE

Directory of Open Access Journals (Sweden)

Leonardo Ferreira Kaltner

2014-07-01

Full Text Available This paper consists in a study of interdisciplinary perspectives that arise in the translation of scientific texts, from the Translation Studies, Linguistics, Textlinguistik (Text Linguistic and Latin Language. Here is the translation of an excerpt from Historia Naturalis Palmarum (Natural History of Palms, written in the nineteenth century by the botanist Carl Friedrich Philipp von Martius (1794-1868, a pioneer in the description of the Brazilian flora.

77 FR 33472 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2012-06-06

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Health Sciences Special Emphasis Panel International Collaborations in Environmental Health. Date: June....D., Scientific Review Administrator, Nat. Institute of Environmental Health Sciences, Office of...

78 FR 14562 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2013-03-06

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Health Sciences Special Emphasis Panel; Studies on Environmental Health Concerns from Superstorm Sandy... Administrator, National Institute of Environmental Health Sciences, Office of Program Operations, Scientific...

Translation teaching in Macao’s polytechnic education

Directory of Open Access Journals (Sweden)

Maria de Lurdes Nogueira Escaleira

2013-03-01

Full Text Available This article "Translation teaching in Higher Education in Macau at the Polytechnic" aims to discuss the issues around teaching and learning of Chinese / Portuguese Translation in Macau, and the role played by the Macau Polytechnic Institute in translators training. For more than four centuries, Macau has been a place of intercultural contact where the Portuguese and the Chinese, now the current official languages, have coexisted and implied constant translation efforts; today, Macau is seen as an important platform between the People's Republic of China and Portuguese Speaking Countries, which has stressed the importance of translation professionals. Despite several attempts, Macau’s public higher education was only established in 1991, as well as a translation degree program; until then, and for more than a century, the translators training was held by a government department. We will discuss several curricular structures implemented over the years in the Macao Polytechnic Institute for training translators who can intermediate between Chinese and Portuguese languages and cultures growingly expanding in Macau, given the significant increase in the demand for properly trained translators/interpreters

The Community Mentorship Program: Providing Community-Engagement Opportunities for Early-Stage Clinical and Translational Scientists to Facilitate Research Translation.

Science.gov (United States)

Patino, Cecilia M; Kubicek, Katrina; Robles, Marisela; Kiger, Holly; Dzekov, Jeanne

2017-02-01

A goal of the Southern California Clinical and Translational Science Institute (SC-CTSI) at the University of Southern California and Children's Hospital Los Angeles is to train early-stage clinical and translational scientists (CTSs) to conduct research that improves the health of diverse communities. This goal aligns well with the Institute of Medicine's recommendations emphasizing community engagement in biomedical research that facilitates research translation. The Community Mentorship Program (CMP), created to complement community-engaged research didactics, matches CTSs with community mentors who help them identify and complete community-engaged experiences that inform their research. The CMP was piloted in 2013-2015 by the SC-CTSI Workforce Development and Community Engagement cores. The CMP team matched three CTSs (assistant professors pursuing mentored career development awards) with mentors at community-based organizations (CBOs) aligned with their research interests. Each mentor-mentee pair signed a memorandum of understanding. The CMP team checked in regularly, monitoring progress and addressing challenges in CTSs' completion of their community-engaged experience. Each pair completed at least one community-engaged activity informing the CTS's research. In exit interviews, the CTSs and CBO mentors expressed satisfaction with the program and stated that they would continue to work together. The CTSs reported that the program provided opportunities to develop networks outside academia, build trust within the community, and receive feedback and learn from individuals in communities affected by their research. The CMP will be expanded to include all eligible early-career CTSs and promoted for use in similar settings outside the SC-CTSI.

78 FR 12369 - United States Government Policy for Institutional Oversight of Life Sciences Dual Use Research of...

Science.gov (United States)

2013-02-22

... Oversight of Life Sciences Dual Use Research of Concern AGENCY: Office of Science and Technology Policy... comments on the proposed United States Government Policy for Institutional Oversight of Life Sciences Dual... requirements for certain categories of life sciences research at institutions that accept Federal funding for...

76 FR 31620 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

Science.gov (United States)

2011-06-01

... Health Sciences Special Emphasis Panel, Research on Ethics and Integrity of Human and or Animal Subjects... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of..., DVM, Chief, Scientific Review Branch, Division of Extramural Research and Training, National Institute...

Annual report of National Institute of Radiological Sciences, April 1993 - March 1994

International Nuclear Information System (INIS)

1995-03-01

This report summarized briefly the research activities and achievements in the Institute for fiscal year 1993 (from April 1993 through March 1994). At the end of this period, the construction of HIMAC has been completed and preparatory experiments of physical and biological studies necessary to the clinical trial have started by use of the heavy ion beams of HIMAC itself. The Institute is covering a wide range of comprehensive radiological sciences from molecular biology to environmental studies and medicine including engineering for heavy ion therapy of cancer. Therefore, the topics collected in the main part have been classified into five categories (physics, chemistry, bio-medical sciences, clinical research and environmental sciences). (J.P.N.)

Annual report of National Institute of Radiological Sciences, April 1993 - March 1994

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-03-01

This report summarized briefly the research activities and achievements in the Institute for fiscal year 1993 (from April 1993 through March 1994). At the end of this period, the construction of HIMAC has been completed and preparatory experiments of physical and biological studies necessary to the clinical trial have started by use of the heavy ion beams of HIMAC itself. The Institute is covering a wide range of comprehensive radiological sciences from molecular biology to environmental studies and medicine including engineering for heavy ion therapy of cancer. Therefore, the topics collected in the main part have been classified into five categories (physics, chemistry, bio-medical sciences, clinical research and environmental sciences). (J.P.N.).

75 FR 34147 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2010-06-16

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Review Branch, Division of Extramural Research and Training, Nat. Institute Environmental Health Sciences... Development in the Environmental Health Sciences; 93.113, Biological Response to Environmental Health Hazards...

78 FR 51734 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2013-08-21

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory..., Nat. Institute of Environmental Health Sciences, Office of Program Operations, Scientific Review... Development in the Environmental Health Sciences; 93.113, Biological Response to Environmental Health Hazards...

75 FR 32797 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2010-06-09

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Branch, Division of Extramural Research and Training, Nat. Institute of Environmental Health Sciences, P... Manpower Development in the Environmental Health Sciences; 93.113, Biological Response to Environmental...

77 FR 61771 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

Science.gov (United States)

2012-10-11

... Environmental Health Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory... clearly unwarranted invasion of personal privacy. Name of Committee: Environmental Health Sciences Review... applications. Place: National Institute of Environmental Health Sciences, Building 101, Rodbell Auditorium, 111...

78 FR 27410 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2013-05-10

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory..., Nat. Institute of Environmental Health Sciences, Office of Program Operations, Scientific Review... the Environmental Health Sciences; 93.113, Biological Response to Environmental Health Hazards; 93.114...

Translating psychological science: Highlighting the media's contribution to contagion in mass shootings: Comment on Kaslow (2015).

Science.gov (United States)

Perrin, Paul B

2016-01-01

In her presidential address, N. J. Kaslow (see record 2015-33530-002) argued that psychologists have a responsibility to translate psychological science to the public and identifies various platforms for doing so. In this comment on her article, I advocate that psychology as a field immediately heed her call in the area of psychological science highlighting the media's contribution to contagion in mass shootings. I point out the psychological science documenting media contagion for suicide and mass shootings, the World Health Organization's (2008) guidelines for media in reporting suicide deaths to prevent that contagion, and discuss ways-based on Dr. Kaslow's suggestions-that psychologists can disseminate psychological science to prevent similar tragedies in the future. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Secondary science teachers' view toward and classroom translation of sustained professional development

Science.gov (United States)

Lewis, Elizabeth Blake

This study concerns the phenomenon of secondary science teacher learning and enacting instructional strategies learned at the Communication in Science Inquiry Project (CISIP) teacher professional development events, as well as teacher perception of, and relationship to, this year-long professional development program. The CISIP program teaches science teachers how to build scientific classroom discourse communities with their students. Some of the science teachers were previous participants in the professional development, and acted as mentor teachers. The research design employed an integrated conceptual framework of situated learning theory with an analytical lens of teachers' professional, institutional and affinity, identities. A multi-method approach was used to generate data. Throughout the 2007-2008 academic year, the teachers' fidelity to the professional development model was measured using a classroom observation instrument aligned with the professional development model. From these observation data a longitudinal model, using hierarchical linear modeling, was constructed. In addition, surveys and interview data were used to construct both whole group and case studies of two high school science teachers who taught biology at the same school. The results indicated that there was a significant difference between previous and new participants; specifically, the longer teachers had participated in the professional development, and adopted a mentorship role, the greater their fidelity of classroom instruction to the CISIP model. Additionally, the case study teacher who developed a CISIP model-aligned affinity identity implemented more of the instructional strategies than the teacher who maintained his school-based institutional identity.

Africa Centre for Systematic Reviews and Knowledge Translation ...

International Development Research Centre (IDRC) Digital Library (Canada)

Africa Centre for Systematic Reviews and Knowledge Translation ... It will also establish greater self-reliance for evidence synthesis and knowledge translation to bridge the gaps between research and health policy. ... Institution. Makerere University. Pays d' institution. Uganda. Site internet. http://www.makerere.ac.ug ...

(CEPTSA) — Translating and Explanatory Dictionaries

African Journals Online (AJOL)

The phases of the project, consisting of different translating and explanatory versions, are discussed. ... already published, namely the Dictionary category of the South African Translators' Institute (SATI) (2003), ... AJOL African Journals Online.

Research in Institutional Economics in Management Science

DEFF Research Database (Denmark)

Foss, Kirsten; Foss, Nicolai Juul

This report maps research in institutional economics in management science in the European Union for the 1995 to 2002 period. The reports applies Internet search based on a university listing, search on journal databases, key informants and an internet-based survey. 195 researchers are identified....... In (sub-)disciplinary terms, organization, strategy, corporate governance, and international business are the major areas of application of institutional economics ideas. In terms of countries, the EU strongholds are Holland, Denmark, UK, and Germany. There is apparently no or very little relevant...... research in Ireland, Portugal, Luxembourg and Greece. Based on the findings of the report, it seems warranted to characterize the EU research effort in the field as being rather dispersed and uncoordinated. Thus, there are no specialized journals, associations or PhD courses. This state of affairs...

75 FR 63843 - National Institute of General Medical Sciences; Notice of Closed Meeting

Science.gov (United States)

2010-10-18

... Sciences Special Emphasis Panel; Review of Minority Biomedical Research Neuro Grant Applications. Date... General Medical Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... of General Medical Sciences, National Institutes of Health, Natcher Building, Room 3AN18J, Bethesda...

78 FR 25754 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2013-05-02

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... of Extramural Research and Training, Nat. Institute of Environmental Health Science, P.O. Box 12233... Health Sciences; 93.113, Biological Response to Environmental Health Hazards; 93.114, Applied...

76 FR 52672 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2011-08-23

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory.... of Environmental Health Sciences, Keystone Building, 530 Davis Drive, Research Triangle Park, NC..., Division of Extramural Research and Training, Nat. Institute of Environmental Health Sciences, P.O. Box...

78 FR 39739 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2013-07-02

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... clearly unwarranted invasion of personal privacy. Name of Committee: Environmental Health Sciences Review... Research and Training, National Institute of Environmental Health Sciences, P.O. Box 12233, MD EC-30...

78 FR 14312 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

Science.gov (United States)

2013-03-05

... Environmental Health Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory... Health Sciences Special Emphasis Panel; Understanding Environmental Control of Epigenetic/Mechanisms... Extramural Research and Training, Nat. Institute of Environmental Health Sciences, P.O. Box 12233, MD EC-30...

75 FR 61765 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

Science.gov (United States)

2010-10-06

... Environmental Health Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory... Environmental Health Sciences Special Emphasis Panel, Superfund Research and Training Program. Date: October 26...-Tilotta, PhD, Scientific Review Officer, Nat. Institute of Environmental Health Sciences, Office of...

77 FR 30019 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2012-05-21

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... of Extramural Research and Training, Nat. Institute of Environmental Health Science, P.O. Box 12233... Health Sciences; 93.113, Biological Response to Environmental Health Hazards; 93.114, Applied...

Development of a replicable process for translating science into practical health education messages.

Science.gov (United States)

Tyus, Nadra C; Freeman, Randall J; Gibbons, M Christopher

2006-09-01

There has been considerable discussion about translating science into practical messages, especially among urban minority and "hard-to-reach" populations. Unfortunately, many research findings rarely make it back in useful format to the general public. Few innovative techniques have been established that provide researchers with a systematic process for developing health awareness and prevention messages for priority populations. The purpose of this paper is to describe the early development and experience of a unique community-based participatory process used to develop health promotion messages for a predominantly low-income, black and African-American community in Baltimore, MD. Scientific research findings from peer-reviewed literature were identified by academic researchers. Researchers then taught the science to graphic design students and faculty. The graphic design students and faculty then worked with both community residents and researchers to transform this information into evidence-based public health education messages. The final products were culturally and educationally appropriate, health promotion messages reflecting urban imagery that were eagerly desired by the community. This early outcome is in contrast to many previously developed messages and materials created through processes with limited community involvement and by individuals with limited practical knowledge of local community culture or expertise in marketing or mass communication. This process may potentially be utilized as a community-based participatory approach to enhance the translation of scientific research into desirable and appropriate health education messages.

75 FR 65363 - National Institute of General Medical Sciences; Notice of Closed Meeting

Science.gov (United States)

2010-10-22

... Sciences Special Emphasis Panel; Review of Minority Biomedical Research Neuro Grant Applications. Date... General Medical Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... General Medical Sciences, National Institutes of Health, Natcher Building, Room 3AN18J, Bethesda, MD 20892...

78 FR 18359 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

Science.gov (United States)

2013-03-26

... Environmental Health Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory... Training, Nat. Institute of Environmental Health Sciences, P.O. Box 12233, MD EC-30, Research Triangle Park... Environmental Health Sciences Special Emphasis Panel; Research Careers in Emerging Technologies. Date: April 30...

77 FR 60445 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

Science.gov (United States)

2012-10-03

... Environmental Health Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory... Research and Training, National Institute of Environmental Health Science, P.O. Box 12233, MD EC-30/Room... Environmental Health Sciences Special Emphasis Panel; Support for Conferences and Scientific Meetings. Date...

78 FR 8156 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2013-02-05

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Environmental Health Sciences Special Emphasis Panel; Studies of Environmental Agents to Induce Immunotoxicity... Research and Training, Nat. Institute of Environmental Health Sciences, P.O. Box 12233, MD EC-30, Research...

76 FR 13650 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

Science.gov (United States)

2011-03-14

... Environmental Health Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory... Training, Nat. Institute of Environmental Health Sciences, P.O. Box 12233, MD EC-30/Room 3171, Research... Environmental Health Sciences Special Emphasis Panel; Review of Educational Grants with an Environmental Health...

76 FR 62080 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2011-10-06

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... clearly unwarranted invasion of personal privacy. Name of Committee: Environmental Health Sciences Review... Extramural Research and Training, Nat'l Institute of Environmental Health Sciences, P.O. Box 12233, MD EC-30...

75 FR 10293 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2010-03-05

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory.... Institute Environmental Health Sciences, P. O. Box 12233, MD EC-30, Research Triangle Park, NC 27709, (919... Health Sciences; 93.113, Biological Response to Environmental Health Hazards; 93.114, Applied...

Translating Health Services Research into Practice in the Safety Net.

Science.gov (United States)

Moore, Susan L; Fischer, Ilana; Havranek, Edward P

2016-02-01

To summarize research relating to health services research translation in the safety net through analysis of the literature and case study of a safety net system. Literature review and key informant interviews at an integrated safety net hospital. This paper describes the results of a comprehensive literature review of translational science literature as applied to health care paired with qualitative analysis of five key informant interviews conducted with senior-level management at Denver Health and Hospital Authority. Results from the literature suggest that implementing innovation may be more difficult in the safety net due to multiple factors, including financial and organizational constraints. Results from key informant interviews confirmed the reality of financial barriers to innovation implementation but also implied that factors, including institutional respect for data, organizational attitudes, and leadership support, could compensate for disadvantages. Translating research into practice is of critical importance to safety net providers, which are under increased pressure to improve patient care and satisfaction. Results suggest that translational research done in the safety net can better illuminate the special challenges of this setting; more such research is needed. © Health Research and Educational Trust.

Annual report of National Institute of Radiological Sciences, 2004

International Nuclear Information System (INIS)

2005-10-01

The fiscal year 2004 was the 4th year since the National Institute of Radiological Sciences (NIRS) reformed as an Independent Administrative Institution (IAI) in April 2001. The main items of this report, being the same as the previous year's, are: the summary of NIRS activities; research and development including studies of important project, fundamental research, fundamental and frontier research, contract research and fact-finding; management; organization/budget/finance; and appendix. Important projects are radiological studies in advanced medicine, on sensitivity, of effects on human and of hazard. Fundamental research concerns studies of environmental radiation, radiobiology, heavy particle ion therapy, diagnostic imaging, dose assessment and protection in medical radiation, brain function, systematic basic technology of nuclear sciences and international cooperation. Fact-finding studies are on the present situations of people exposed by nuclear experiment at Bikini Atoll in 1954 and of patients treated with thorotrast in past. Appendix cites the personnel name list, honorable events, cooperative studies, patent situation and others. (J.P.N.)

PERSPECTIVE: Translational neural engineering: multiple perspectives on bringing benchtop research into the clinical domain

Science.gov (United States)

Rousche, Patrick; Schneeweis, David M.; Perreault, Eric J.; Jensen, Winnie

2008-03-01

strongly encouraged open industrial academic partnerships as an efficient path forward in the translational process. Joe Pancrazio, PhD, a Program Director at NIH's National Institute of Neurological Disorders and Stroke, emphasized that NIH funding for translational research was aimed at breaking down scientific barriers to clinic entrance. Vivian Weil, PhD, (Director of Center for the Study of Ethics in the Professions at the Illinois Institute of Technology) a specialist on ethics in science and engineering, spoke of the usefulness of developing a code of ethics for addressing ethical aspects of translation from the bench to clinical implementation and of translation across disciplines in multi-disciplinary projects. Finally, the patient perspective was represented by Mr Jesse Sullivan. A double-arm amputee and patient of Dr Kuiken's, Mr Sullivan demonstrated the critically important role of the patient in successful translational neural engineering research.

75 FR 45133 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2010-08-02

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory.... Institute of Environmental Health Science, P.O. Box 12233, MD EC-30/Room 3170 B, Research Triangle Park, NC... Manpower Development in the Environmental Health Sciences; 93.113, Biological Response to Environmental...

77 FR 61613 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

Science.gov (United States)

2012-10-10

... Environmental Health Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory... Environmental Health Sciences, P. O. Box 12233, MD EC-30, Research Triangle Park, NC 27709, (919) 541-1307, [email protected] . Name of Committee: National Institute of Environmental Health Sciences Special Emphasis...

75 FR 68367 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2010-11-05

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Research and Training, Nat. Institute of Environmental Health Science, P.O. Box 12233, MD EC-30/Room 3170 B... Sciences; 93.113, Biological Response to Environmental Health Hazards; 93.114, Applied Toxicological...

76 FR 26311 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2011-05-06

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory.... Institute of Environmental Health Sciences, P.O. Box 12233, MD EC-30/Room 3171, Research Triangle Park, NC... and Education; 93.894, Resources and Manpower Development in the Environmental Health Sciences; 93.113...

Energy balance at a crossroads: translating the science into action.

Science.gov (United States)

Manore, Melinda M; Brown, Katie; Houtkooper, Linda; Jakicic, John; Peters, John C; Smith Edge, Marianne; Steiber, Alison; Going, Scott; Gable, Lisa Guillermin; Krautheim, Ann Marie

2014-07-01

One of the major challenges facing the United States is the high number of overweight and obese adults and the growing number of overweight and unfit children and youth. To improve the nation's health, young people must move into adulthood without the burden of obesity and its associated chronic diseases. To address these issues, the American College of Sports Medicine, the Academy of Nutrition and Dietetics, and the US Department of Agriculture/Agriculture Research Service convened an expert panel meeting in October 2012 titled "Energy Balance at a Crossroads: Translating the Science into Action." Experts in the fields of nutrition and exercise science came together to identify the biological, lifestyle, and environmental changes that will most successfully help children and families attain and manage energy balance and tip the scale toward healthier weights. Two goals were addressed: 1) professional training and 2) consumer/community education. The training goal focused on developing a comprehensive strategy to facilitate the integration of nutrition and physical activity (PA) using a dynamic energy balance approach for regulating weight into the training of undergraduate and graduate students in dietetics/nutrition science, exercise science/PA, and pre-K-12 teacher preparation programs and in training existing cooperative extension faculty. The education goal focused on developing strategies for integrating dynamic energy balance into nutrition and PA educational programs for the public, especially programs funded by federal/state agencies. The meeting expert presenters and participants addressed three key areas: 1) biological and lifestyle factors that affect energy balance, 2) undergraduate/graduate educational and training issues, and 3) best practices associated with educating the public about dynamic energy balance. Specific consensus recommendations were developed for each goal.

Research in progress at the Institute for Computer Applications in Science and Engineering

Science.gov (United States)

1987-01-01

This report summarizes research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics, numerical analysis, and computer science during the period April 1, 1987 through October 1, 1987.

New FINESSE Faculty Institutes for NASA Earth and Space Science Education

Science.gov (United States)

Slater, Timothy F.; Slater, Stephanie; Marshall, Sunette Sophia; Stork, Debra; Pomeroy, J. Richard R

2014-06-01

In a systematic effort to improve the preparation of future science teachers, scholars coordinated by the CAPER Center for Astronomy & Physics Education Research are providing a series of high-quality, 2-day professional development workshops, with year-round follow-up support, for college and university professors who prepare future science teachers to work with highly diverse student populations. These workshops focus on reforming and revitalizing undergraduate science teaching methods courses and Earth and Space science content courses that future teachers most often take to reflect contemporary pedagogies and data-rich problem-based learning approaches steeped in authentic scientific inquiry, which consistently demonstrate effectiveness with diverse students. Participants themselves conduct science data-rich research projects during the institutes using highly regarded approaches to inquiry using proven models. In addition, the Institute allocates significant time to illustrating best practices for working with diverse students. Moreover, participants leave with a well-formulated action plan to reform their courses targeting future teachers to include more data-rich scientific inquiry lessons and to be better focused on improving science education for a wide diversity of students. Through these workshops faculty use a backwards faded scaffolding mechanism for working inquiry into a deeper understanding of science by using existing on-line data to develop and research astronomy, progressing from creating a valid and easily testable question, to simple data analysis, arriving at a conclusion, and finally presenting and supporting that conclusion in the classroom. An updated schedule is available at FINESSEProgram.org

Earth Institute at Columbia University ADVANCE Program: Addressing Needs for Women in Earth and Environmental Sciences

Science.gov (United States)

Bell, R. E.; Cane, M.; Mutter, J.; Miller, R.; Pfirman, S.; Laird, J.

2004-12-01

The Earth Institute has received a major NSF ADVANCE grant targeted at increasing the participation and advancement of women scientists and engineers in the Academy through institutional transformation. The Earth Institute at Columbia University includes 9 research institutes including Lamont-Doherty Earth Observatory, Center for Environmental Research and Conservation (CERC), Center for International Earth Science Information Network (CIESIN), International Research Institute (IRI) for Climate Prediction, Earth Engineering Center, NASA-Goddard Institute for Space Studies, Center for Risks and Hazards, Center for Globalization and Sustainable Development, and Center for Global Health and Economic Development and six academic departments including Ecology, Evolution and Environmental Biology (E3B, School of Arts and Sciences), Earth and Environmental Engineering (DEEE, School of Engineering and Applied Sciences), Department of Environmental Health (School of Public Health), Department of Earth and Environmental Sciences (DEES, School of Arts and Sciences), Department of International and Public Affairs (School of International and Policy Affairs), and Barnard College Department of Environmental Science. The Earth Institute at Columbia University's ADVANCE program is based both on a study of the status of women at Columbia and research on the progression of women in science elsewhere. The five major targets of the Columbia ADVANCE program are to (1) change the demographics of the faculty through intelligent hiring practices, (2) provide support to women scientists through difficult life transitions including elder care and adoption or birth of a child, (3) enhance mentoring and networking opportunities, (4) implement transparent promotion procedures and policies, and (5) conduct an institutional self study. The Earth Institute ADVANCE program is unique in that it addresses issues that tend to manifest themselves in the earth and environmental fields, such as extended

Reconceptualising translation in agricultural innovation

NARCIS (Netherlands)

Ingram, Julie; Dwyer, Janet; Gaskell, Peter; Mills, Jane; Wolf, de Pieter

2018-01-01

Scientific research continues to play a significant role in meeting the multiple innovation challenges in agriculture. If this role is to be fulfilled, provision needs to be made for effective translation of research outputs, where translation is understood to be the process whereby science becomes

Google Wave: Have CTSA-Minded Institutions Caught It?

OpenAIRE

Amy Donahue

2010-01-01

Background - Google Wave was touted as the next big communication tool—combining e-mail, social networking, and chat within a single “wave”—with the potential to create a new world for collaboration. Information professionals who are knowledgeable of this tool and its capabilities could become uniquely situated to use it, evaluate it, and teach it. This seemed especially true for those working within Clinical and Translational Science Award (CTSA)-minded institutions, given the promise of int...

76 FR 62422 - National Institute of Environmental Health Sciences; Cancellation of Meeting

Science.gov (United States)

2011-10-07

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Environmental Health Sciences; Cancellation of Meeting Notice is hereby given of the cancellation of the Interagency Breast Cancer and Environmental Research Coordinating Committee, October 12, 2011, 1 p.m. to 3 p.m...

The Brave New Researcher of Doctoral Integrity Training in the Heath Sciences

DEFF Research Database (Denmark)

Sarauw, Laura Louise

2018-01-01

as points of reference for an overall discussion of the implied ideas about the ideal researcher in a comparative cross-faculty perspective: 1) Translations between international/national/institutional and local/faculty ideas about what problems the integrity training is expected to solve, 2) Translations......The presented material is a part of a wider, comparative ethnography in which we study the emerging integrity training for PhD fellows provided by four different faculties: Science, Humanities, Social Science and Business, and Health. The comparison comprises the following themes that will serve...... between standardisations of curriculum and content, local development and ideas about what problems integrity training is expected to solve. 3) Translations between ideas about adequate pedagogies and ideas about what problems integrity training is expected to solve...

78 FR 59944 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2013-09-30

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Institute of Environmental Health Sciences, P.O. Box 12233, MD EC-30, Research Triangle Park, NC 27709, (919... [[Page 59945

Ghana Space Science and Technology Institute (GSSTI) - Annual Report 2015

International Nuclear Information System (INIS)

2015-01-01

The Ghana Space Science and Technology Institute (GSSTI) of the Ghana Atomic Energy Commission was established to exploit space science and technology for socio-economic development of Ghana. The report gives the structure of GSSTI and the detailed activities of the year. Various activities include: training and seminars, projects and workshops. Publications and their abstracts are also listed. The report also highlights some of the challenges, provides some recommendations and points to some expectation for the following year.

Polish Academy of Sciences Institute of Biochemistry and Biophysics research report 1994-1995

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-12-31

Scientific interests of Institute of Biochemistry and Biophysics Polish Academy of Sciences are focused on DNA replication and repair, gene expression, gene sequencing and molecular biophysics. The work reviews research projects of the Institute in 1994-1995.

Polish Academy of Sciences Institute of Biochemistry and Biophysics research report 1994-1995

International Nuclear Information System (INIS)

1996-01-01

Scientific interests of Institute of Biochemistry and Biophysics Polish Academy of Sciences are focused on DNA replication and repair, gene expression, gene sequencing and molecular biophysics. The work reviews research projects of the Institute in 1994-1995

Polish Academy of Sciences Institute of Biochemistry and Biophysics research report 1994-1995

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-12-31

Scientific interests of Institute of Biochemistry and Biophysics Polish Academy of Sciences are focused on DNA replication and repair, gene expression, gene sequencing and molecular biophysics. The work reviews research projects of the Institute in 1994-1995.

A university system's approach to enhancing the educational mission of health science schools and institutions: the University of Texas Academy of Health Science Education

Directory of Open Access Journals (Sweden)

L. Maximilian Buja

2013-03-01

Full Text Available Background: The academy movement developed in the United States as an important approach to enhance the educational mission and facilitate the recognition and work of educators at medical schools and health science institutions. Objectives: Academies initially formed at individual medical schools. Educators and leaders in The University of Texas System (the UT System, UTS recognized the academy movement as a means both to address special challenges and pursue opportunities for advancing the educational mission of academic health sciences institutions. Methods: The UTS academy process was started by the appointment of a Chancellor's Health Fellow for Education in 2004. Subsequently, the University of Texas Academy of Health Science Education (UTAHSE was formed by bringing together esteemed faculty educators from the six UTS health science institutions. Results: Currently, the UTAHSE has 132 voting members who were selected through a rigorous, system-wide peer review and who represent multiple professional backgrounds and all six campuses. With support from the UTS, the UTAHSE has developed and sustained an annual Innovations in Health Science Education conference, a small grants program and an Innovations in Health Science Education Award, among other UTS health science educational activities. The UTAHSE represents one university system's innovative approach to enhancing its educational mission through multi- and interdisciplinary as well as inter-institutional collaboration. Conclusions: The UTAHSE is presented as a model for the development of other consortia-type academies that could involve several components of a university system or coalitions of several institutions.

The interplay of post-translational modification and gene therapy

Directory of Open Access Journals (Sweden)

Osamor VC

2016-02-01

Full Text Available Victor Chukwudi Osamor,1–3 Shalom N Chinedu,3,4 Dominic E Azuh,3,5 Emeka Joshua Iweala,3,4 Olubanke Olujoke Ogunlana3,4 1Covenant University Bioinformatics Research (CUBRe Unit, Department of Computer and Information Sciences, College of Science and Technology (CST, Covenant University, Ota, Ogun State, Nigeria; 2Institute of Informatics (Computational biology and Bioinformatics, Faculty of Mathematics, Informatics and Mechanics, University of Warsaw (Uniwersytet Warszawski, Warszawa, Poland; 3Covenant University Public Health and Well-being Research Group (CUPHWERG, Covenant University, 4Biochemistry and Molecular Biology Unit, Department of Biological Sciences, College of Science and Technology, Covenant University, Canaan Land, 5Department of Economics and Development Studies, Covenant University, Ota, Ogun State, Nigeria Abstract: Several proteins interact either to activate or repress the expression of other genes during transcription. Based on the impact of these activities, the proteins can be classified into readers, modifier writers, and modifier erasers depending on whether histone marks are read, added, or removed, respectively, from a specific amino acid. Transcription is controlled by dynamic epigenetic marks with serious health implications in certain complex diseases, whose understanding may be useful in gene therapy. This work highlights traditional and current advances in post-translational modifications with relevance to gene therapy delivery. We report that enhanced understanding of epigenetic machinery provides clues to functional implication of certain genes/gene products and may facilitate transition toward revision of our clinical treatment procedure with effective fortification of gene therapy delivery. Keywords: post-translational modification, gene therapy, epigenetics, histone, methylation

Radiological and Medical Sciences Research Institute (RAMSRI) - Annual Report 2015

International Nuclear Information System (INIS)

2015-01-01

The Radiological and Medical Sciences Research Institute (RAMSRI) is the fourth Research and Development Institute of the Ghana Atomic Energy Commission (GAEC), undertaking research in human health and nutrition. This annual report covers the major activities undertaken by RAMSRI for the year 2015. The activities are grouped under the following headings: Establishment; Personnel and Organisation; Major Activities of Centres; Ongoing IAEA TC Projects; Human Resource Development; IAEA Coordinated Meetings Hosted; Publications; Achievements; Challenges; Projections for the Year 2016; and Recommendations.

Management information system of research institute supported by ministry of science and technology

International Nuclear Information System (INIS)

1992-12-01

This book mentions development strategy of MIS. This book contains development strategy of MIS research institute supported by government, computerization of administrative work of research institute, library computer system, methodology on system development, LAN build of ministry science and technology, ocean data base energy data base, computerization of research data management case of construction and analysis for chemical DB, information system of life science, electronic data interchange, queueing theory, biotechnology and computer, comprehensive weather information system, special equipment of data and data processing of oil-hunt operation.

Management information system of research institute supported by ministry of science and technology

Energy Technology Data Exchange (ETDEWEB)

NONE

1992-12-15

This book mentions development strategy of MIS. This book contains development strategy of MIS research institute supported by government, computerization of administrative work of research institute, library computer system, methodology on system development, LAN build of ministry science and technology, ocean data base energy data base, computerization of research data management case of construction and analysis for chemical DB, information system of life science, electronic data interchange, queueing theory, biotechnology and computer, comprehensive weather information system, special equipment of data and data processing of oil-hunt operation.

77 FR 58111 - Notice of Submission for OMB Review; Institute of Education Sciences; FAFSA Completion Project...

Science.gov (United States)

2012-09-19

... DEPARTMENT OF EDUCATION Notice of Submission for OMB Review; Institute of Education Sciences; FAFSA Completion Project Evaluation SUMMARY: The Institute of Education Sciences (IES) at the U.S. Department of Education (ED) is conducting a rigorous study of the Free Application for Federal Student Aid...

Translational research needs us to go back to basics and collaborate: interview with Lars Sundstrom.

Science.gov (United States)

Sundstrom, Lars

2016-09-01

Lars Sundstrom is Director of Enterprise and Translation at the West of England Academic Health Sciences Network [1] (UK), a Professor of Practice in Translational Medicine and Co-Director of the Elizabeth Blackwell Institute for Health Research at Bristol University [2] (UK), and an honorary Professor of Medicine at Cardiff University (UK). He has extensive experience in translational medicine and clinical neurosciences, holding positions at several eminent universities. He has also held executive and board-level positions at several SMEs, developing new therapeutics for neurological conditions and tools for drug discovery. He has also been an advisor to several UK and local government task forces and to the European Commission and the European Federation of Pharmaceutical Industry Associations. He was a founding member of the European Brain Council in Brussels, and set up the Severnside Alliance for Translational Research, developing a regional network partnership to link clinical and basic scientists. He was also involved in the creation of Health Research Wales.

Science-policy interaction in the global greenhouse. Institutional design and institutional performance in the Intergovernmental Panel on Climate Change (IPCC)

Energy Technology Data Exchange (ETDEWEB)

Skodvin, Tora

1999-08-01

This paper explores the science-policy interaction and the extent to which and how institutional arrangements may be used as instruments for enhancing the effectiveness of the dialog. The first part develops the theory. The point of departure of the analysis is the internal dynamics of science and politics in their pure forms and the nature of the dynamics that are generated when these two distinct systems of behaviour meet. On this basis, then, the question of which functions the institutional apparatus should be able to serve in order to enhance the effectiveness of science-policy dialogue is addressed. This approach is then applied to an empirical case study of the Intergovernmental Panel on Climate Change (IPCC) from its establishment in 1988 to the provision of the Second IPCC Assessment Report in 1995. 53 refs., 3 figs., 2 tabs.

Annual Report of National Institute of Radiological Sciences, April 1991 - March 1992

International Nuclear Information System (INIS)

1992-07-01

This annual report is a compilation of the research activities and achievement in the National Institute of Radiological Sciences (NIRS) in Japan during the fiscal year 1991 (from April 1991 through March 1992). The research covers a wide range of radiological sciences from molecular to environmental studies and medicine including engineering. Topics consists of physics, chemistry, biomedical science, clinical research, and environmental sciences, covering a total of 69 titles. A list of publications by staff members, activities of research divisions, and organization chart of the NIRS are given in Appendix. (J.P.N.) 64 refs

Pseudo-realia in the Romanian Translations of Various Hungarian Institutions and in the Hungarian Translations of Romanian Public Administration Terms

Directory of Open Access Journals (Sweden)

Zopus Andras

2016-12-01

Full Text Available My presentation addresses an issue translators of Romanian–Hungarian legal and economic texts encounter almost day by day. Each field of translation is special in its kind, but translating legal/economic texts requires an especially accurate knowledge of the acts, laws, and concepts of both the source and target language since this is essential for the translated text to be really a quality, professional, and – last but not least – an intelligible one to the target-language audience, i.e. the customers.

Findings of the 2014 Workshop on Statistical Machine Translation

NARCIS (Netherlands)

Bojar, O.; Buck, C.; Federmann, C.; Haddow, B.; Koehn, P.; Leveling, J.; Monz, C.; Pecina, P.; Post, M.; Saint-Amand, H.; Soricut, R.; Specia, L.; Tamchyna, A.

2014-01-01

This paper presents the results of the WMT14 shared tasks, which included a standard news translation task, a separate medical translation task, a task for run-time estimation of machine translation quality, and a metrics task. This year, 143 machine translation systems from 23 institutions were

77 FR 4572 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2012-01-30

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Development in the Environmental Health Sciences; 93.113, Biological Response to Environmental Health Hazards... clearly unwarranted invasion of personal privacy. Name of Committee: National Institute of Environmental...

75 FR 41506 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2010-07-16

... Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Sciences; 93.113, Biological Response to Environmental Health Hazards; 93.114, Applied Toxicological... clearly unwarranted invasion of personal privacy. Name of Committee: National Institute of Environmental...

Translating Regenerative Biomaterials Into Clinical Practice.

Science.gov (United States)

Stace, Edward T; Dakin, Stephanie G; Mouthuy, Pierre-Alexis; Carr, Andrew J

2016-01-01

Globally health care spending is increasing unsustainably. This is especially true of the treatment of musculoskeletal (MSK) disease where in the United States the MSK disease burden has doubled over the last 15 years. With an aging and increasingly obese population, the surge in MSK related spending is only set to worsen. Despite increased funding, research and attention to this pressing health need, little progress has been made toward novel therapies. Tissue engineering and regenerative medicine (TERM) strategies could provide the solutions required to mitigate this mounting burden. Biomaterial-based treatments in particular present a promising field of potentially cost-effective therapies. However, the translation of a scientific development to a successful treatment is fraught with difficulties. These barriers have so far limited translation of TERM science into clinical treatments. It is crucial for primary researchers to be aware of the barriers currently restricting the progression of science to treatments. Researchers need to act prospectively to ensure the clinical, financial, and regulatory hurdles which seem so far removed from laboratory science do not stall or prevent the subsequent translation of their idea into a treatment. The aim of this review is to explore the development and translation of new treatments. Increasing the understanding of these complexities and barriers among primary researchers could enhance the efficiency of biomaterial translation. © 2015 Wiley Periodicals, Inc.

Summary of research in applied mathematics, numerical analysis and computer science at the Institute for Computer Applications in Science and Engineering

Science.gov (United States)

1984-01-01

Research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics, numerical analysis and computer science during the period October 1, 1983 through March 31, 1984 is summarized.

NASA's Solar System Exploration Research Virtual Institute: Merging Science and Exploration

Science.gov (United States)

Pendleton, Y. J.; Schmidt, G. K.; Bailey, B. E.; Minafra, J. A.

2016-01-01

NASA's Solar System Exploration Research Virtual Institute (SSERVI) represents a close collaboration between science, technology and exploration, and was created to enable a deeper understanding of the Moon and other airless bodies. SSERVI is supported jointly by NASA's Science Mission Directorate and Human Exploration and Operations Mission Directorate. The institute currently focuses on the scientific aspects of exploration as they pertain to the Moon, Near Earth Asteroids (NEAs) and the moons of Mars, but the institute goals may expand, depending on NASA's needs, in the future. The 9 initial teams, selected in late 2013 and funded from 2014-2019, have expertise across the broad spectrum of lunar, NEA, and Martian moon sciences. Their research includes various aspects of the surface, interior, exosphere, near-space environments, and dynamics of these bodies. NASA anticipates a small number of additional teams to be selected within the next two years, with a Cooperative Agreement Notice (CAN) likely to be released in 2016. Calls for proposals are issued every 2-3 years to allow overlap between generations of institute teams, but the intent for each team is to provide a stable base of funding for a five year period. SSERVI's mission includes acting as a bridge between several groups, joining together researchers from: 1) scientific and exploration communities, 2) multiple disciplines across a wide range of planetary sciences, and 3) domestic and international communities and partnerships. The SSERVI central office is located at NASA Ames Research Center in Mountain View, CA. The administrative staff at the central office forms the organizational hub for the domestic and international teams and enables the virtual collaborative environment. Interactions with geographically dispersed teams across the U.S., and global partners, occur easily and frequently in a collaborative virtual environment. This poster will provide an overview of the 9 current US teams and

NASA's Solar System Exploration Research Virtual Institute: Merging Science and Exploration

Science.gov (United States)

Pendleton, Yvonne J.

2016-10-01

Established in 2013, through joint funding from the NASA Science Mission Directorate (SMD) and Human Exploration and Operations Mission Directorate (HEOMD), NASA's Solar System Exploration Research Virtual Institute (SSERVI) is focused on science at the intersection of these two enterprises. Addressing questions of value to the human exploration program that also represent important research relevant to planetary science, SSERVI creates a bridge between HEOMD and SMD. The virtual institute model reduces travel costs, but its primary virtue is the ability to join together colleagues who bring the right expertise, techniques and tools, regardless of their physical location, to address multi-faceted problems, at a deeper level than could be achieved through the typical period of smaller research grants. In addition, collaboration across team lines and international borders fosters the creation of new knowledge, especially at the intersections of disciplines that might not otherwise overlap.SSERVI teams investigate the Moon, Near-Earth Asteroids, and the moons of Mars, addressing questions fundamental to these target bodies and their near space environments. The institute is currently composed of nine U.S. teams of 30-50 members each, distributed geographically across the United States, ten international partners, and a Central Office located at NASA Ames Research Center in Silicon Valley, CA. U.S. teams are competitively selected through peer-reviewed proposals submitted to NASA every 2-3 years, in response to a Cooperative Agreement Notice (CAN). The current teams were selected under CAN-1, with funding for five years (2014-2019). A smaller, overlapping set of teams are expected to be added in 2017 in response to CAN-2, thereby providing continuity and a firm foundation for any directional changes NASA requires as the CAN-1 teams end their term. This poster describes the research areas and composition of the institute to introduce SSERVI to the broader planetary

75 FR 46950 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2010-08-04

... Health Sciences Special Emphasis Panel, Gulf Oil Spill Health Effects. Date: August 17, 2010. Time: 1 p.m...--Health Risks from Environmental Exposures; 93.142, NIEHS Hazardous Waste Worker Health and Safety... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of...

Studies on the Mental Processes in Translation Memory-assisted Translation – the State of the Art

DEFF Research Database (Denmark)

Christensen, Tina Paulsen

2011-01-01

This article reviews research on the mental translation processes involved in translation memory-assisted translation. First, based on recent developments in cognitive science the article provides a working definition of mental TM research. Next the article analyses a selection of mental TM studies...... with a view to discovering their aims, data, methods and results. In doing so, the paper attempts to find out what we know by now about the mental aspects of translation memory-assisted translation. The analysis suggests fruitful avenues for future research and concludes that particularly more research...... is needed which takes into account the recent developments within TM technology and looks into both internal and external translation processes....

Science Information Centre and Nuclear Library of 'Jozef Stefan' Institute, Ljubljana, Slovenia

International Nuclear Information System (INIS)

Stante, A.; Smuc, S.

2006-01-01

The 'Jozef Stefan' Institute Science Information Centre is the central Slovene physics library and one of the largest special libraries in Slovenia. Our collection covers the fields of physics, chemistry, biochemistry, electronics, information science, artificial intelligence, energy management, environmental science, material science, robotics etc. The Nuclear Library at the Reactor Centre Podgorica is a part of the Science Information Centre. It collects and keeps literature from the field of reactor and nuclear energy and provides information to scientists employed at the Reactor Centre and users from the Nuclear Power Plant Krsko as well as other experts dealing with nuclear science and similar fields. The orders subscribed are sent by the Science Information Centre to other libraries included in inter-library lending in Slovenia and abroad. (author)

Climate change, uncertainty, and resilient fisheries: Institutional responses through integrative science

DEFF Research Database (Denmark)

Miller, K.; Charles, A.; Barange, M.

2010-01-01

This paper explores the importance of a focus on the fundamental goals of resilience and adaptive capacity in the governance of uncertain fishery systems, particularly in the context of climate change. Climate change interacts strongly with fishery systems, and adds to the inherent uncertainty...... that understanding these aspects of fishery systems and fishery governance is valuable even in the absence of climate-induced processes of change, but that attention to climate change both reinforces the need for, and facilitates the move toward, implementation of integrative science for improved fishery governance....... and processes – to support suitable institutional responses, a broader planning perspective, and development of suitable resilience-building strategies. The paper explores how synergies between institutional change and integrative science can facilitate the development of more effective fisheries policy...

Suborganizations of Institutions in Library and Information Science Journals

Directory of Open Access Journals (Sweden)

Dalibor Fiala

2013-10-01

Full Text Available In this paper, we analyze Web of Science data records of articles published from 1991 to 2010 in library and information science (LIS journals. We focus on addresses of these articles’ authors and create citation and collaboration networks of departments which we define as the first suborganization of an institution. We present various rankings of departments (e.g., by citations, times cited, PageRank, publications, etc. and highlight the most influential of them. The correlations between the individual departments are also shown. Furthermore, we visualize the most intense citation and collaboration relationships between “LIS” departments (many of which are not genuine LIS departments but merely affiliations of authors publishing in journals covered by the specific Web of Science category and give examples of two basic research performance distributions across departments of the leading universities in the field.

U.S. Institutional Research Productivity in Major Science Education Research Journals: Top 30 for 2000's

Science.gov (United States)

Barrow, Lloyd H.; Tang, Nai-en

2013-01-01

VonAalst (2010) used Google Scholar to identify the top four science education research journals: "Journal of Research in Science Teaching," "Science Education," "International Journal of Science Education," and "Journal of Science Teacher Education." U.S. institutional productivity for 2000-2009 for the…

Inequality in societies, academic institutions and science journals: Gini and k-indices

Science.gov (United States)

Ghosh, Asim; Chattopadhyay, Nachiketa; Chakrabarti, Bikas K.

2014-09-01

Social inequality is traditionally measured by the Gini-index (g). The g-index takes values from 0 to 1 where g=0 represents complete equality and g=1 represents complete inequality. Most of the estimates of the income or wealth data indicate the g value to be widely dispersed across the countries of the world: g values typically range from 0.30 to 0.65 at a particular time (year). We estimated similarly the Gini-index for the citations earned by the yearly publications of various academic institutions and the science journals. The ISI web of science data suggests remarkably strong inequality and universality (g=0.70±0.07) across all the universities and institutions of the world, while for the journals we find g=0.65±0.15 for any typical year. We define a new inequality measure, namely the k-index, saying that the cumulative income or citations of (1-k) fraction of people or papers exceed those earned by the fraction (k) of the people or publications respectively. We find, while the k-index value for income ranges from 0.60 to 0.75 for income distributions across the world, it has a value around 0.75±0.05 for different universities and institutions across the world and around 0.77±0.10 for the science journals. Apart from above indices, we also analyze the same institution and journal citation data by measuring Pietra index and median index.

Information Retrieval Diary of an Expert Technical Translator.

Science.gov (United States)

Cremmins, Edward T.

1984-01-01

Recommends use of entries from the information retrieval diary of Ted Crump, expert technical translator at the National Institute of Health, in the construction of computer models showing how expert translators solve problems of ambiguity in language. Expert and inexpert translation systems, eponyms, abbreviations, and alphabetic solutions are…

A Model for Strengthening Collaborative Research Capacity: Illustrations from the Atlanta Clinical Translational Science Institute

Science.gov (United States)

Rodgers, Kirsten C.; Akintobi, Tabia; Thompson, Winifred Wilkins; Evans, Donoria; Escoffery, Cam; Kegler, Michelle C.

2014-01-01

Introduction: Community-engaged research is effective in addressing health disparities but may present challenges for both academic institutions and community partners. Therefore, the need to build capacity for conducting collaborative research exists. The purpose of this study is to present a model for building research capacity in…

Equity in Elementary Science Education: A Study of Institutional and Policy Factors

Science.gov (United States)

Hayes, Kathryn N.

Despite recognition that the foundation for interest in science is laid down at the elementary level (Tai, et al., 2006), in the last ten years elementary science instruction time has declined in K-6 schooling (Center on Education Policy, 2007). A lack of access to excellent science education is exacerbated for low-income students, prompting significant questions regarding inequities within the science education pipeline (Maulucci, 2010). The critical factors needed to address these inequities include teacher preparation, access to resources, and instructional leadership, as well as a supportive policy and institutional milieu. However, although the former three have been studied extensively, the role of policy and institutions in creating the conditions for equity in science education are little understood despite their likely significant role (Lemke, 2001). This mixed methods study addressed this gap by examining the role the policy and institutional milieu play in constraining or supporting equitable elementary science education. Institutional theory provides the framework for understanding how various institutional logics and regulatory pressures permeate schools and districts across contexts, influencing science education implementation (Scott, 2014). Two distinct approaches were used to first quantitatively examine the predictors of differentiation in elementary science education instructional time and methods, and second qualitatively analyze the nature and process by which these mechanisms exert influence. Data for the first two papers was derived from a case study of a purposively sampled district, including surveys of 200 teachers and embedded case studies of four schools. Analysis consisted of multi-level models of teacher attributes and school and policy factors in predicting differential distribution of science education instructional time and methods (Raudenbush & Bryk, 2002). Data for the third paper arose out of a series of principal, administrator

Cyberinfrastructure for Open Science at the Montreal Neurological Institute.

Science.gov (United States)

Das, Samir; Glatard, Tristan; Rogers, Christine; Saigle, John; Paiva, Santiago; MacIntyre, Leigh; Safi-Harab, Mouna; Rousseau, Marc-Etienne; Stirling, Jordan; Khalili-Mahani, Najmeh; MacFarlane, David; Kostopoulos, Penelope; Rioux, Pierre; Madjar, Cecile; Lecours-Boucher, Xavier; Vanamala, Sandeep; Adalat, Reza; Mohaddes, Zia; Fonov, Vladimir S; Milot, Sylvain; Leppert, Ilana; Degroot, Clotilde; Durcan, Thomas M; Campbell, Tara; Moreau, Jeremy; Dagher, Alain; Collins, D Louis; Karamchandani, Jason; Bar-Or, Amit; Fon, Edward A; Hoge, Rick; Baillet, Sylvain; Rouleau, Guy; Evans, Alan C

2016-01-01

Data sharing is becoming more of a requirement as technologies mature and as global research and communications diversify. As a result, researchers are looking for practical solutions, not only to enhance scientific collaborations, but also to acquire larger amounts of data, and to access specialized datasets. In many cases, the realities of data acquisition present a significant burden, therefore gaining access to public datasets allows for more robust analyses and broadly enriched data exploration. To answer this demand, the Montreal Neurological Institute has announced its commitment to Open Science, harnessing the power of making both clinical and research data available to the world (Owens, 2016a,b). As such, the LORIS and CBRAIN (Das et al., 2016) platforms have been tasked with the technical challenges specific to the institutional-level implementation of open data sharing, including: Comprehensive linking of multimodal data (phenotypic, clinical, neuroimaging, biobanking, and genomics, etc.)Secure database encryption, specifically designed for institutional and multi-project data sharing, ensuring subject confidentiality (using multi-tiered identifiers).Querying capabilities with multiple levels of single study and institutional permissions, allowing public data sharing for all consented and de-identified subject data.Configurable pipelines and flags to facilitate acquisition and analysis, as well as access to High Performance Computing clusters for rapid data processing and sharing of software tools.Robust Workflows and Quality Control mechanisms ensuring transparency and consistency in best practices.Long term storage (and web access) of data, reducing loss of institutional data assets.Enhanced web-based visualization of imaging, genomic, and phenotypic data, allowing for real-time viewing and manipulation of data from anywhere in the world.Numerous modules for data filtering, summary statistics, and personalized and configurable dashboards. Implementing

Annual report of national institute of radiological sciences, April 1990 - March 1991

International Nuclear Information System (INIS)

1991-07-01

This annual report is a compilation of the research activities and achievement in the National Institute of Radiological Sciences (NIRS) in Japan during the fiscal year 1990 (from April 1990 through March 1991). The research covers a wide range of radiological sciences from molecular to environmental studies and medicine including engineering. Topics consists of physics, chemistry, bio-medical science, clinical research, and environmental sciences, covering a total of 86 titles. A list of publications by staff members, activities of research divisions, and organization chart of the NIRS are given in Appendix. (J.P.N.) 102 refs

International student exchange and the medical curriculum: evaluation of a medical sciences translational physiology course in Brazil.

Science.gov (United States)

Morris, Mariana; Jones, T David; Rocha, Maria Jose Alves; Fazan, Rubens; Chapleau, Mark W; Salgado, Helio C; Johnson, Alan Kim; Irigoyen, Maria Claudia; Michelini, Lisete C; Goldstein, David L

2006-09-01

The objective of the present study was to conduct a short-term international course on translational physiology for medical students from Wright State University and the University of Iowa. The goals were to 1) provide students with an exposure to the academic, cultural, and medical environments in Brazil; 2) promote awareness of the global medical community; and 3) provide an academic course focused on translational physiology. An evaluation of the students was conducted to determine whether such a short-term course might be useful in the medical curriculum. The 2-wk course was held in the summer of 2005 at the University of São Paulo School of Medicine in Ribeirão Preto, Brazil, for 23 American students. The program included presentations of basic and clinical topics, meetings with medical students, and clinical presentations. The program finished with student attendance at a scientific meeting sponsored by the Brazilian Society of Hypertension. Student surveys evaluated issues related to perceived treatment, Brazilian medical school environment, culture and personal attributes, and career aspirations. The international Medical Sciences Translational Physiology course for medical students provided a brief, but intense, experience. It gave students a picture of the medical environment in Brazil and an appreciation for the differences and similarities in cultures. Most students reported that it was a positive experience that would be beneficial to their careers. In conclusion, a short-term international course provides an efficient means for medical students to experience aspects of global medical science.

Communicating Ocean Sciences to Informal Audiences (COSIA): Universities, Oceanographic Institutions, Science Centers and Aquariums Working Together to Improve Ocean Education and Public Outreach

Science.gov (United States)

Glenn, S.; McDonnell, J.; Halversen, C.; Zimmerman, T.; Ingram, L.

2007-12-01

Ocean observatories have already demonstrated their ability to maintain long-term time series, capture episodic events, provide context for improved shipboard sampling, and improve accessibility to a broader range of participants. Communicating Ocean Sciences, an already existing college course from COSEE-California has demonstrated its ability to teach future scientists essential communication skills. The NSF-funded Communicating Ocean Sciences to Informal Audiences (COSIA) project has leveraged these experiences and others to demonstrate a long-term model for promoting effective science communication skills and techniques applicable to diverse audiences. The COSIA effort is one of the pathfinders for ensuring that the new scientific results from the increasing U.S. investments in ocean observatories is effectively communicated to the nation, and will serve as a model for other fields. Our presentation will describe a long-term model for promoting effective science communication skills and techniques applicable to diverse audiences. COSIA established partnerships between informal science education institutions and universities nationwide to facilitate quality outreach by scientists and the delivery of rigorous, cutting edge science by informal educators while teaching future scientists (college students) essential communication skills. The COSIA model includes scientist-educator partnerships that develop and deliver a college course that teaches communication skills through the understanding of learning theory specifically related to informal learning environments and the practice of these skills at aquariums and science centers. The goals of COSIA are to: provide a model for establishing substantive, long-term partnerships between scientists and informal science education institutions to meet their respective outreach needs; provide future scientists with experiences delivering outreach and promoting the broader impact of research; and provide diverse role models

Beyond Translation

DEFF Research Database (Denmark)

Olwig, Mette Fog

2013-01-01

This article contributes to the growing scholarship on local development practitioners by re-examining conceptualizations of practitioners as ‘brokers’ strategically translating between ‘travelling’ (development institution) rationalities and ‘placed’ (recipient area) rationalities in relation...... and practice spurred by new challenges deriving from climate change anxiety, the study shows how local practitioners often make local activities fit into travelling development rationalities as a matter of habit, rather than as a conscious strategy. They may therefore cease to ‘translate’ between different...... rationalities. This is shown to have important implications for theory, research and practice concerning disaster risk reduction and climate change adaptation in which such translation is often expected....

Annual report of National Institute of Radiological Science, April 1994 -March 1995

International Nuclear Information System (INIS)

1996-03-01

This annual report summarizes briefly the research activities and the achievement in the Institute for fiscal year of 1994 (from April 1994 to March 1995). As the middle of this period, commissioning of the new clinical trial of cancer treatment was successfully started using heavy ion beams of the HIMAC (heavy ion medical accelerator in Chiba) which was completed at the end of fiscal year 1993. At the same time, various kinds of basic research projects using the same heavy ion beams were also begun in an open use system available to many facilities outside the Institute. The Institute is covering a very wide area of comprehensive radiological sciences from molecular biology to environmental studies and radiation medicine including physics and engineering related to therapy and diagnosis. Therefore, the collected topics have been classified into several categories from physics to environmental science. The appendix of this report includes recent publication in each area, list of keywords, author, index, and organization and staff. (M.N.)

Annual report of National Institute of Radiological Science, April 1994 - March 1995

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-03-01

This annual report summarizes briefly the research activities and the achievement in the Institute for fiscal year of 1994 (from April 1994 to March 1995). As the middle of this period, commissioning of the new clinical trial of cancer treatment was successfully started using heavy ion beams of the HIMAC (heavy ion medical accelerator in Chiba) which was completed at the end of fiscal year 1993. At the same time, various kinds of basic research projects using the same heavy ion beams were also begun in an open use system available to many facilities outside the Institute. The Institute is covering a very wide area of comprehensive radiological sciences from molecular biology to environmental studies and radiation medicine including physics and engineering related to therapy and diagnosis. Therefore, the collected topics have been classified into several categories from physics to environmental science. The appendix of this report includes recent publication in each area, list of keywords, author, index, and organization and staff. (M.N.)

Annual report of National Institute for Fusion Science. April 2013 - March 2014

International Nuclear Information System (INIS)

2014-01-01

This annual report summarizes achievements from research activities at the National Institute for Fusion Science (NIFS) between April 2013 and March 2014. NIFS is an inter-university research organization and conducts open collaboration research under three frameworks which are the General Collaboration Research, the Large Helical Device Collaboration Research and the Bilateral Collaboration Research. More than 500 collaborating studies were implemented during the covered period. About 2,400 collaborators studies were implemented during the covered period. About 2,400 collaborators participated in joint research from 220 external institutions. Many intensively advanced results in plasma physics, fusion science and related fields have been obtained from these studies. Not only NIFS, but also 6 university centers serve as joint research laboratories/centers under bilateral collaboration research. NIFS also organizes diversified frameworks for international collaboration through 6 bilateral agreements, 3 multi-lateral agreements and academic exchange agreements with 18 institutes abroad for the global development of the function of inter-university research organization. (J.P.N.)

Radiological and Medical Sciences Research Institute, Ghana Atomic Energy Commission: Annual Report 2014

International Nuclear Information System (INIS)

2014-01-01

The Radiological and Medical Sciences Research Institute was established in 2009, as the forth research institute of the Ghana Atomic Energy Commission. This Annual Report provides an overview of the major activities of the Institutes in the year 2014. Major items covered in the report include: Strategic objectives; Collaborations; Personnel and Organisational Structure; Facilities and Technical Services; Summary of Research and Development Projects; Human Resource Development; Publications and Technical Reports.

76 FR 19104 - National Institute of General Medical Sciences; Notice of Closed Meeting

Science.gov (United States)

2011-04-06

... General Medical Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... clearly unwarranted invasion of personal privacy. Name of Committee: National Institute of General Medical Sciences Special Emphasis Panel; 2011 NIH Director's Pioneer Awards. Date: May 2-4, 2011. Time: 7:45 a.m...

Eliminating the Neglected Tropical Diseases: Translational Science and New Technologies.

Directory of Open Access Journals (Sweden)

Peter J Hotez

2016-03-01

Full Text Available Today, the World Health Organization recognizes 17 major parasitic and related infections as the neglected tropical diseases (NTDs. Despite recent gains in the understanding of the nature and prevalence of NTDs, as well as successes in recent scaled-up preventive chemotherapy strategies and other health interventions, the NTDs continue to rank among the world's greatest global health problems. For virtually all of the NTDs (including those slated for elimination under the auspices of a 2012 London Declaration for NTDs and a 2013 World Health Assembly resolution [WHA 66.12], additional control mechanisms and tools are needed, including new NTD drugs, vaccines, diagnostics, and vector control agents and strategies. Elimination will not be possible without these new tools. Here we summarize some of the key challenges in translational science to develop and introduce these new technologies in order to ensure success in global NTD elimination efforts.

NATO Advanced Research Institute on the Application of Systems Science to Energy Policy Planning

CERN Document Server

Cherniavsky, E; Laughton, M; Ruff, L

1981-01-01

The Advanced Research Institute (ARI) on "The Application of Systems Science to Energy Policy Planning" was held under the auspices of the NATO Special Programme Panel on Systems Science in collaboration with the National Center for Analysis of Energy Sys­ tems, Brookhaven National Laboratory, USA, as a part of the NATO Science Committee's continuous effort to promote the advancement of science through international cooperation. Advanced Research Institutes are sponsored by the NATO Science Committee for the purposes of bringing together senior scientists to seek consensus on an assessment of the present state of knowl­ edge on a specific topic and to make recommendations for future research directions. Meetings are structured to encourage inten­ sive group discussion. Invitees are carefully selected so that the group as a whole will contain the experience and expertise neces­ sary to make the conclusions valid and significant. A final report is published presenting the various viewpoints and conclusions....

Synergies and Distinctions between Computational Disciplines in Biomedical Research: Perspective from the Clinical and Translational Science Award Programs

Science.gov (United States)

Bernstam, Elmer V.; Hersh, William R.; Johnson, Stephen B.; Chute, Christopher G.; Nguyen, Hien; Sim, Ida; Nahm, Meredith; Weiner, Mark; Miller, Perry; DiLaura, Robert P.; Overcash, Marc; Lehmann, Harold P.; Eichmann, David; Athey, Brian D.; Scheuermann, Richard H.; Anderson, Nick; Starren, Justin B.; Harris, Paul A.; Smith, Jack W.; Barbour, Ed; Silverstein, Jonathan C.; Krusch, David A.; Nagarajan, Rakesh; Becich, Michael J.

2010-01-01

Clinical and translational research increasingly requires computation. Projects may involve multiple computationally-oriented groups including information technology (IT) professionals, computer scientists and biomedical informaticians. However, many biomedical researchers are not aware of the distinctions among these complementary groups, leading to confusion, delays and sub-optimal results. Although written from the perspective of clinical and translational science award (CTSA) programs within academic medical centers, the paper addresses issues that extend beyond clinical and translational research. The authors describe the complementary but distinct roles of operational IT, research IT, computer science and biomedical informatics using a clinical data warehouse as a running example. In general, IT professionals focus on technology. The authors distinguish between two types of IT groups within academic medical centers: central or administrative IT (supporting the administrative computing needs of large organizations) and research IT (supporting the computing needs of researchers). Computer scientists focus on general issues of computation such as designing faster computers or more efficient algorithms, rather than specific applications. In contrast, informaticians are concerned with data, information and knowledge. Biomedical informaticians draw on a variety of tools, including but not limited to computers, to solve information problems in health care and biomedicine. The paper concludes with recommendations regarding administrative structures that can help to maximize the benefit of computation to biomedical research within academic health centers. PMID:19550198

Science Hall of Atomic Energy in Research Reactor Institute, Kyoto University

International Nuclear Information System (INIS)

Hayashi, Takeo

1979-01-01

The Science Hall of Atomic Energy was built as a subsidiary facility of the Research Reactor Institute, Kyoto University. The purpose of this facility is to accept outside demands concerning the application of the research reactor. The building is a two story building, and has the floor area of 901.47 m 2 . There are an exhibition room, a library, and a big lecture room. In the exhibition room, models of the Kyoto University Research Reactor and the Kyoto University Critical Assembly are placed. Various pictures concerning the application of the reactor are on the wall. In the library, people from outside of the Institute can use various books on science. Books for boys and girls are also stocked and used for public use. At the lecture room, various kinds of meeting can be held. (Kato, T.)

Solving the Puzzle of Recruitment and Retention-Strategies for Building a Robust Clinical and Translational Research Workforce.

Science.gov (United States)

Nearing, Kathryn A; Hunt, Cerise; Presley, Jessica H; Nuechterlein, Bridget M; Moss, Marc; Manson, Spero M

2015-10-01

This paper is the first in a five-part series on the clinical and translational science educational pipeline and presents strategies to support recruitment and retention to create diverse pathways into clinical and translational research (CTR). The strategies address multiple levels or contexts of persistence decisions and include: (1) creating a seamless pipeline by forming strategic partnerships to achieve continuity of support for scholars and collective impact; (2) providing meaningful research opportunities to support identity formation as a scientist and sustain motivation to pursue and persist in CTR careers; (3) fostering an environment for effective mentorship and peer support to promote academic and social integration; (4) advocating for institutional policies to alleviate environmental pull factors; and, (5) supporting program evaluation-particularly, the examination of longitudinal outcomes. By combining institutional policies that promote a culture and climate for diversity with quality, evidence-based programs and integrated networks of support, we can create the environment necessary for diverse scholars to progress successfully and efficiently through the pipeline to achieve National Institutes of Health's vision of a robust CTR workforce. © 2015 Wiley Periodicals, Inc.

Translating Alcohol Research: Opportunities and Challenges.

Science.gov (United States)

Batman, Angela M; Miles, Michael F

2015-01-01

Alcohol use disorder (AUD) and its sequelae impose a major burden on the public health of the United States, and adequate long-term control of this disorder has not been achieved. Molecular and behavioral basic science research findings are providing the groundwork for understanding the mechanisms underlying AUD and have identified multiple candidate targets for ongoing clinical trials. However, the translation of basic research or clinical findings into improved therapeutic approaches for AUD must become more efficient. Translational research is a multistage process of stream-lining the movement of basic biomedical research findings into clinical research and then to the clinical target populations. This process demands efficient bidirectional communication across basic, applied, and clinical science as well as with clinical practitioners. Ongoing work suggests rapid progress is being made with an evolving translational framework within the alcohol research field. This is helped by multiple interdisciplinary collaborative research structures that have been developed to advance translational work on AUD. Moreover, the integration of systems biology approaches with collaborative clinical studies may yield novel insights for future translational success. Finally, appreciation of genetic variation in pharmacological or behavioral treatment responses and optimal communication from bench to bedside and back may strengthen the success of translational research applications to AUD.

Harvard Catalyst | The Clinical Translational Science Center IND/IDE Consult Service: providing an IND/IDE consult service in a decentralized network of academic healthcare centers.

Science.gov (United States)

Kim, Min J; Winkler, Sabune J; Bierer, Barbara E; Wolf, Delia

2014-04-01

The Food and Drug Administration (FDA) regulations require sponsors of clinical investigations involving an investigational drug or device to submit an Investigational New Drug (IND) or Investigational Device Exemption (IDE) application. Strict adherence to applicable regulations is vital to the success of clinical research. Unlike most major pharmaceutical sponsors, investigator sponsors often do not fully appreciate their regulatory obligations nor have resources to ensure compliance. As a result they can place themselves and their institutions at risk. Nevertheless, investigator-initiated clinical trials are vital to the further development of innovative drugs, biologics, and medical devices. The IND/IDE Subcommittee under the Regulatory Knowledge and Support Program at Harvard Catalyst, The Harvard Clinical and Translational Science Center worked in collaboration with Harvard and Harvard affiliated institutions to create and launch an IND/IDE Consult Service in a decentralized network of collaborating Academic Healthcare Centers (AHC). The IND/IDE Consult Service offers expertise, resources, and shared experiences to assist sponsor-investigators and IRBs in meeting regulatory requirements for conducting and reviewing investigator-initiated IND/IDE studies. The scope of the services provided by the Harvard Catalyst IND/IDE Consult Service are described, including the specifics of the service, lessons learned, and challenges faced, in a scalable model that builds inter-institutional capacity. © 2014 Wiley Periodicals, Inc.

Harvard Catalyst | The Clinical Translational Science Center IND/IDE Consult Service: Providing an IND/IDE Consult Service in a Decentralized Network of Academic Healthcare Centers

Science.gov (United States)

Winkler, Sabune J.; Bierer, Barbara E.; Wolf, Delia

2014-01-01

Abstract The Food and Drug Administration (FDA) regulations require sponsors of clinical investigations involving an investigational drug or device to submit an Investigational New Drug (IND) or Investigational Device Exemption (IDE) application. Strict adherence to applicable regulations is vital to the success of clinical research. Unlike most major pharmaceutical sponsors, investigator sponsors often do not fully appreciate their regulatory obligations nor have resources to ensure compliance. As a result they can place themselves and their institutions at risk. Nevertheless, investigator‐initiated clinical trials are vital to the further development of innovative drugs, biologics, and medical devices. The IND/IDE Subcommittee under the Regulatory Knowledge and Support Program at Harvard Catalyst, The Harvard Clinical and Translational Science Center worked in collaboration with Harvard and Harvard affiliated institutions to create and launch an IND/IDE Consult Service in a decentralized network of collaborating Academic Healthcare Centers (AHC). The IND/IDE Consult Service offers expertise, resources, and shared experiences to assist sponsor‐investigators and IRBs in meeting regulatory requirements for conducting and reviewing investigator‐initiated IND/IDE studies. The scope of the services provided by the Harvard Catalyst IND/IDE Consult Service are described, including the specifics of the service, lessons learned, and challenges faced, in a scalable model that builds inter‐institutional capacity. PMID:24455986

Relationships between academic institutions and industry in the life sciences--an industry survey.

Science.gov (United States)

Blumenthal, D; Causino, N; Campbell, E; Louis, K S

1996-02-08

Despite growing acceptance of relationships between academia and industry in the life sciences, systematic, up-to-date information about their extent and the consequences for the parties involved remains scarce. We attempted to collect information about the prevalence, magnitude, commercial benefits, and potential risks of such relationships by surveying a representative sample of life-science companies in the United States to determine their relationships with academic institutions. We collected data by telephone from May through September 1994 from senior executives of 210 life-science companies (of 306 companies surveyed; response rate, 69 percent). The sample contained all Fortune 500 companies in the fields of agriculture, chemicals, and pharmaceuticals; all international pharmaceutical companies with sales volumes similar to those of the Fortune 500 companies; and a random sample of non-Fortune 500 companies in the life sciences drawn from multiple commercial and noncommercial directories. Both the survey instrument and the survey methods resembled those of our 1984 study of 106 biotechnology companies, allowing us to assess the evolution of relationships between academia and industry over the past decade. Ninety percent of companies conducting life-science research in the United States had relationships involving the life sciences with an academic institution in 1994. Fifty-nine percent supported research in such institutions, providing an estimated $1.5 billion, or approximately 11.7 percent of all research-and-development funding received that year. The agreements with universities tended to be short-term and to involve small amounts, implying that most such relationships supported applied research or development. Over 60 percent of companies providing support for life-science research in universities had received patents, products, and sales as a result of those relationships. At the same time, the companies reported that their relationships with

In Brief: Science teaching certificate

Science.gov (United States)

Showstack, Randy

2008-11-01

More than 200 educators will receive fellowships over the next 5 years to participate in NASA's Endeavor Science Teaching Certificate Project, the agency announced on 14 November. Through workshops, online and on-site graduate courses, and NASA educational materials, the project will expose educators to NASA science and engineering and support them in translating the information for use in classrooms. ``Through the program, educators will learn to deliver cutting-edge science into the classroom, promoting science, technology, engineering, and mathematics education,'' according to Joyce Winterton, assistant administrator for education at NASA Headquarters, in Washington, D. C. Project fellows will earn a certificate from Teachers College Innovations at Teachers College, Columbia University, New York, and graduate credit from other institutional partners. For more information, visit http://education.nasa.gov/home/index.html.

Psychoanalytic peregrinations. III: Confusion of tongues, psychoanalyst as translator.

Science.gov (United States)

Chessick, Richard D

2002-01-01

A variety of problems cause a confusion of tongues between the psychoanalyst and the patient. In this sense the psychoanalyst faces the same problems as the translator of a text from one language to another. Examples are given of confusion due cultural differences, confusion due translation differences among translators, confusion due translator prejudice or ignorance, confusion due ambiguous visual cues and images, and confusion due to an inherently ambiguous text. It is due to this unavoidable confusion that the humanistic sciences cannot in principle achieve the mathematical exactness of the natural sciences and should not be expected to do so or condemned because they do not.

A little something from physics for medicine (Scientific session of the Physical Sciences Division of the Russian Academy of Sciences, 23 April 2014)

International Nuclear Information System (INIS)

2014-01-01

A scientific session of the Physical Sciences Division of the Russian Academy of Sciences (RAS), entitled 'A little something from physics for medicine', was held on 23 April 2014 at the conference hall of the Lebedev Physical Institute, RAS. The agenda posted on the website of the Physical Sciences Division, RAS, http://www.gpad.ac.ru, included the following reports: (1) Rumyantsev S A (D Rogachev Federal Research and Clinical Center of Pediatric Hematology, Oncology, and Immunology, Moscow) 'Translational medicine as a basis of progress in hematology/oncology'; (2) Akulinichev S V (Institute for Nuclear Research, RAS, Moscow) 'Promising nuclear medicine research at the INR, RAS'; (3) Nikitin P P (Prokhorov General Physics Institute, RAS, Moscow) 'Biosensorics: new possibilities provided by marker-free optical methods and magnetic nanoparticles for medical diagnostics'; (4) Alimpiev S S, Nikiforov S M, Grechnikov A A (Prokhorov General Physics Institute, RAS, Moscow) 'New approaches in laser mass-spectrometry of organic objects'. The publication of the article based on the oral report No. 2 is presented below. • Promising nuclear medicine research in the Institute for Nuclear Research, Russian Academy of Sciences, V V Akulinichev Physics-Uspekhi, 2014, Volume 57, Number 12, Pages 1239–1243 (conferences and symposia)

Summary of research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics, numerical analysis and computer science

Science.gov (United States)

1989-01-01

Research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics, numerical analysis, and computer science during the period October 1, 1988 through March 31, 1989 is summarized.

The BIG Data Center: from deposition to integration to translation.

Science.gov (United States)

2017-01-04

Biological data are generated at unprecedentedly exponential rates, posing considerable challenges in big data deposition, integration and translation. The BIG Data Center, established at Beijing Institute of Genomics (BIG), Chinese Academy of Sciences, provides a suite of database resources, including (i) Genome Sequence Archive, a data repository specialized for archiving raw sequence reads, (ii) Gene Expression Nebulas, a data portal of gene expression profiles based entirely on RNA-Seq data, (iii) Genome Variation Map, a comprehensive collection of genome variations for featured species, (iv) Genome Warehouse, a centralized resource housing genome-scale data with particular focus on economically important animals and plants, (v) Methylation Bank, an integrated database of whole-genome single-base resolution methylomes and (vi) Science Wikis, a central access point for biological wikis developed for community annotations. The BIG Data Center is dedicated to constructing and maintaining biological databases through big data integration and value-added curation, conducting basic research to translate big data into big knowledge and providing freely open access to a variety of data resources in support of worldwide research activities in both academia and industry. All of these resources are publicly available and can be found at http://bigd.big.ac.cn. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

Forty years of the Institute for Nuclear Research (Scientific session of the Physical Sciences Division of the Russian Academy of Sciences, 22 December 2010)

International Nuclear Information System (INIS)

2011-01-01

On 22 December 2010, the scientific session of the Physical Sciences Division of the Russian Academy of Sciences (RAS), devoted to the 40th anniversary of the Institute for Nuclear Research, RAS, was held at the Institute for Nuclear Research, RAS in Troitsk. The agenda of the session announced on the website www.gpad.ac.ru of the RAS Physical Sciences Division listed the following reports: (1) Matveev V A (Institute for Nuclear Research, RAS, Moscow) ''Introductory word''; (2) Gavrin V N (Institute for Nuclear Research, RAS, Moscow) ''Contribution of the SAGE results to the understanding of solar physics and neutrino physics''; (3) Domogatsky G V (Institute for Nuclear Research, RAS, Moscow) ''Baikal neutrino experiment''; (4) Tkachev I I (Institute for Nuclear Research, RAS, Moscow) ''Observation of the Greisen - Zatsepin - Kuz'min effect at the Telescope Array Observatory''; (5) Kudenko Yu G (Institute for Nuclear Research, RAS, Moscow) ''Neutrino T2K experiment: the first results''; (6) Sadykov R A (Institute for Nuclear Research, RAS, Moscow) ''Fields of study of condensed media at the neutron facility at the INR, RAS''; (7) Zhuikov B L (Institute for Nuclear Research, RAS, Moscow) ''Production of isotopes at the INR, RAS: reality and prospects''. The papers written on the base of reports 1-5 and 7 are published below. In addition, the paper ''High-power diode-pumped alkali lasers'' by A M Shalagin is published. The paper is based on the report presented at the scientific session of the General Assembly of the Physical Sciences Division, RAS (13 December 2010) devoted to the 50th anniversary of the laser, the main materials of the session having been published in Usp. Fiz. Nauk 181 (8) 867 (2011) [Phys. Usp. 54 837 (2011)]. . Institute for Nuclear Research of the Russian Academy of Sciences turns 40, V A Matveev Physics-Uspekhi, 2011, Volume 54, Number 9, Pages 939-940 . The Russian-American gallium experiment SAGE, V N Gavrin Physics-Uspekhi, 2011, Volume 54

Science Production in Germany, France, Belgium, and Luxembourg: Comparing the Contributions of Research Universities and Institutes to Science, Technology, Engineering, Mathematics, and Health.

Science.gov (United States)

Powell, Justin J W; Dusdal, Jennifer

2017-01-01

Charting significant growth in science production over the 20th century in four European Union member states, this neo-institutional analysis describes the development and current state of universities and research institutes that bolster Europe's position as a key region in global science. On-going internationalization and Europeanization of higher education and science has been accompanied by increasing competition as well as collaboration. Despite the policy goals to foster innovation and further expand research capacity, in cross-national and historical comparison neither the level of R&D investments nor country size accounts completely for the differential growth of scientific productivity. Based on a comprehensive historical database from 1900 to 2010, this analysis uncovers both stable and dynamic patterns of production and productivity in Germany, France, Belgium, and Luxembourg. Measured in peer-reviewed research articles collected in Thomson Reuters' Science Citation Index Expanded, which includes journals in the fields of Science, Technology, Engineering, Mathematics, and Health, we show the varying contributions of different organizational forms, especially research universities and research institutes. Comparing the institutionalization pathways that created the conditions necessary for continuous and strong growth in scientific productivity in the European center of global science emphasizes that the research university is the key organizational form across countries.

Recent fusion research in the National Institute for Fusion Science

International Nuclear Information System (INIS)

Komori, Akio; Sakakibara, Satoru; Sagara, Akio; Horiuchi, Ritoku; Yamada, Hiroshi; Takeiri, Yasuhiko

2011-01-01

The National Institute for Fusion Science (NIFS), which was established in 1989, promotes academic approaches toward the exploration of fusion science for steady-state helical reactor and realizes the establishment of a comprehensive understanding of toroidal plasmas as an inter-university research organization and a key center of worldwide fusion research. The Large Helical Device (LHD) Project, the Numerical Simulation Science Project, and the Fusion Engineering Project are organized for early realization of net current free fusion reactor, and their recent activities are described in this paper. The LHD has been producing high-performance plasmas comparable to those of large tokamaks, and several new findings with regard to plasma physics have been obtained. The numerical simulation science project contributes understanding and systemization of the physical mechanisms of plasma confinement in fusion plasmas and explores complexity science of a plasma for realization of the numerical test reactor. In the fusion engineering project, the design of the helical fusion reactor has progressed based on the development of superconducting coils, the blanket, fusion materials and tritium handling. (author)

Translation initiation factors eIF3 and HCR1 control translation termination and stop codon read-through in yeast cells

Czech Academy of Sciences Publication Activity Database

Beznosková, P.; Cuchalová, Lucie; Wagner, S.; Shoemaker, Ch. J.; Gunišová, S.; von der Haar, T.; Valášek, L. S.

2013-01-01

Roč. 9, č. 11 (2013), e1003962_1-e1003962_17 ISSN 1553-7404 Institutional support: RVO:61389013 Keywords : translation initiation * translation termination * eIF3 Subject RIV: CD - Macromolecular Chemistry Impact factor: 8.167, year: 2013

Radioactive waste treatment at the Boris Kidric Institute of nuclear sciences

International Nuclear Information System (INIS)

Vukovic, Z.

1989-01-01

The results of many years work on the problems of treatment and interim storage of radioactive waste at the Boris Kidric Institute of nuclear sciences are presented. The main R/D work based on chemical treatment, solidification and pressing is described (author)

Radioactive waste treatment at the Boris Kidric Institute of nuclear sciences

Energy Technology Data Exchange (ETDEWEB)

Vukovic, Z [Institute of Nuclear Sciences Boris Kidric, Vinca, Beograd (Serbia and Montenegro)

1989-07-01

The results of many years work on the problems of treatment and interim storage of radioactive waste at the Boris Kidric Institute of nuclear sciences are presented. The main R/D work based on chemical treatment, solidification and pressing is described (author)

Science for education: a new model of translational research applied to education

Directory of Open Access Journals (Sweden)

Roberto Lent

2017-07-01

Full Text Available A great advance in the last transition of centuries has been the consolidation of the concept of translational research, applied with success in Health and Engineering in practically all countries of medium/high GDP. Intriguingly, this has not occurred with Education. It is yet not perceived that Science can already understand how people learn, which are the mechanisms that accelerate learning and teaching, and how this would impact on the economy and the social progress of nations. It is also not perceived that innovations can be validated with populational studies to rationalize and scale novel teaching initiatives, nor which socioemotional competences should future citizens possess to work in companies more and more automatized and informatized. Perhaps because of this omission, the progress of Brazilian educational indicators has been so modest. In Health, public policies not only invest in material improvements (sanitation, hospital attendance, nutritional coverture, etc, but also on Science and Innovation capable of creating new options in the international scenario (therapies for degenerative diseases, vaccines for infectious diseases, etc. Differently, on Education investment has focused exclusively on material improvements (more schools, better salaries for teachers, etc, necessary but insufficient to accelerate growth of our indicators at faster and more competitive rates. This scenario opens to us a window of opportunity to create a new Science policy aiming at Education. To give concreteness to this possibility, the proposal on discussion is that the new initiatives of support and funding by public and private agencies should have Science for Education as its structurant axis.

The effects of integrating service learning into computer science: an inter-institutional longitudinal study

Science.gov (United States)

Payton, Jamie; Barnes, Tiffany; Buch, Kim; Rorrer, Audrey; Zuo, Huifang

2015-07-01

This study is a follow-up to one published in computer science education in 2010 that reported preliminary results showing a positive impact of service learning on student attitudes associated with success and retention in computer science. That paper described how service learning was incorporated into a computer science course in the context of the Students & Technology in Academia, Research, and Service (STARS) Alliance, an NSF-supported broadening participation in computing initiative that aims to diversify the computer science pipeline through innovative pedagogy and inter-institutional partnerships. The current paper describes how the STARS Alliance has expanded to diverse institutions, all using service learning as a vehicle for broadening participation in computing and enhancing attitudes and behaviors associated with student success. Results supported the STARS model of service learning for enhancing computing efficacy and computing commitment and for providing diverse students with many personal and professional development benefits.

SEMANTIC REPRESENTATION AND THE TRANSLATION OF ...

African Journals Online (AJOL)

process, making use of current advances in cognitive science, artificial intelligence and text linguistics, basing .... type of translation - a translator will endeavour to preserve the polyvalent quality of the poem as in the ... plays some part in the life of the text and brings a different background to it. ... of human beliefs, actions,.

Building a translational science on children and youth affected by political violence and armed conflict: A commentary.

Science.gov (United States)

Masten, Ann S

2017-02-01

Articles in this timely Special Section represent an important milestone in the developmental science on children and youth involved in political violence and armed conflict. With millions of children worldwide affected by past and present wars and conflicts, there is an urgent and growing need for research to inform efforts to understand, prevent, and mitigate the possible harm of such violence to individual children, families, communities, and societies, for present as well as future generations. The four programs of research highlighted in this Special Section illustrate key advances and challenges in contemporary development research on young people growing up in the midst or aftermath of political violence. These studies are longitudinal, methodologically sophisticated, and grounded in socioecological systems models that align well with current models of risk and resilience in developmental psychopathology. These studies collectively mark a critically important shift to process-focused research that holds great promise for translational applications. Nonetheless, given the scope of the international crisis of children and youth affected by political violence and its sequelae, there is an urgent global need for greater mobilization of resources to support translational science and effective evidence-based action.

New institutional mechanisms to bridge the information gap between climate science and public policy decisions

Science.gov (United States)

Rogers, W.; Gulledge, J. M.

2010-12-01

Many decision makers lack actionable scientific information needed to prepare for future challenges associated with climate change. Although the scope and quality of available scientific information has increased dramatically in recent years, this information does not always reach - or is not presented in a form that is useful to - decision makers who need it. The producer (i.e. scientists) community tends to be stovepiped, even though consumers (i.e. decision makers) often need interdisciplinary science and analysis. Consumers, who may also be stovepiped in various agencies or subject areas, may lack familiarity with or access to these separate communities, as well as the tools or time to navigate scientific information and disciplines. Closing the communication gap between these communities could be facilitated by institutionalizing processes designed for this purpose. We recommend a variety of mainstreaming policies within the consumer community, as well as mechanisms to generate a strong demand signal that will resonate more strongly with the producer community. We also recommend institutional reforms and methods of incentivizing policy-oriented scientific analysis within the producer community. Our recommendations focus on improving information flow to national security and foreign policy decision makers, but many are relevant to public policy writ large. Recommendations for Producers 1. The scientific community should formally encourage collaborations between natural and social scientists and reward publications in interdisciplinary outlets Incentives could include research funding and honorary awards recognizing service to public policy. 2. Academic merit review should reward research grants and publications targeted at interdisciplinary and/or policy-oriented audiences. Reforms of merit review may require new policies and engaged institutional leadership. Recommendations for Consumers 1. Congress should amend Title VI of the National Defense Education Act

78 FR 56902 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2013-09-16

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Environmental Health Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meeting. The meeting will be closed to the public in accordance...

78 FR 64221 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

Science.gov (United States)

2013-10-28

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Environmental Health Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance...

Health Narratives in the Greek Translated Press

Directory of Open Access Journals (Sweden)

Themis Panagiotis Kaniklidou

2016-08-01

Full Text Available This paper looks see how meaning is constructed in translated news texts about health and science and awards a narrative potential to unforced translation shifts, moving along the theoretical lines of Baker's Narrative Theory (2006. The thematic thread of health zooms in on “emotional frames” (Nabi, 2003 of risk and fear of human health that is narrated as being 'under attack’ by potentially dangerous diseases. Themes also orbit around schemas that promote hope and optimism about science represented as coming to the rescue of man from fear of the disease. The data consists of 21 pairs of English-Greek health news articles culled from the Greek newspapers I Kathimerini, To Vima and Ta Nea. Findings point towards translation as a process that employs lexicogrammatical and intrasentential configurations to a give emphasis to the risk or hope dimensions underlying a heath or science story, b enable the reflection or emergence of a cascade of public, conceptual and master narratives.

Aryabhatta Research Institute of Observational Sciences: reincarnation of a 50 year old State Observatory of Nainital

Science.gov (United States)

Sagar, Ram

2006-03-01

The fifty year old State Observatory, well known as U.P. State Observatory till the formation of Uttaranchal in November 2000, was reincarnated on March 22, 2004 as Aryabhatta Research Institute of Observational Sciences with acronym ARIES, an autonomous institute, under the Department of Science & Technology, Government of India. The growth of academic and technical activities and new mandate of the Institute are briefly described. In early 60's, the Institute was one of the 12 centres established by the Smithsonian Astrophysical Observatory, USA, all over the globe but the only centre in India for imaging artificial earth satellites. Commensurating with its observing capabilities, the Institute started a number of front-line research programmes during the last decade, e.g., optical follow up observations of GRB afterglows, radio and space borne astronomical resources, intra-night optical variability in active galactic nuclei as well as gravitational microlensing and milli-magnitude variations in the rapidly oscillating peculiar A type stars. As a part of atmospheric studies, characterisation of aerosol at an altitude of about 2 km is going on since 2002. ARIES has plans for establishing modern observing facilities equipped with latest backend instruments in the area of both astrophysics and atmospheric science. Formation of ARIES, therefore augurs well for the overall development of astrophysics and atmospheric science in India.

Correlation of Translation and Other Language Activities

Science.gov (United States)

Belenkova, Nataliya; Davtyan, Victoria

2016-01-01

International cooperation in all professional settings makes translation a very important tool of interpersonal and professional relations of specialists in different domains. Training of undergraduates and graduates' translation skills in a special setting is included in the curriculum of non-linguistic higher education institutions and studied…

Engineering in translational medicine

CERN Document Server

2014-01-01

This book covers a broad area of engineering research in translational medicine. Leaders in academic institutions around the world contributed focused chapters on a broad array of topics such as: cell and tissue engineering (6 chapters), genetic and protein engineering (10 chapters), nanoengineering (10 chapters), biomedical instrumentation (4 chapters), and theranostics and other novel approaches (4 chapters). Each chapter is a stand-alone review that summarizes the state-of-the-art of the specific research area. Engineering in Translational Medicine gives readers a comprehensive and in-depth overview of a broad array of related research areas, making this an excellent reference book for scientists and students both new to engineering/translational medicine and currently working in this area.

Annual report-2011. Institute for Nuclear Research National Academy of Sciences of Ukraine

International Nuclear Information System (INIS)

Iivanyuk, F.O.

2012-01-01

Annual report contains information on the fundamental, scientific and applied investigations carried out in the Institute for Nuclear Research of the National Academy of Sciences of Ukraine in the year 2010. The report contains abstracts of research works in the fields of nuclear physics, atomic energy, radiation physics and radiation material science, physics of plasma, radiation ecology and biology.

78 FR 66947 - National Institute of General Medical Sciences; Notice of Closed Meeting

Science.gov (United States)

2013-11-07

... Person: Robert Horowits, Ph.D., Senior Investigator, National Institute of General Medical Sciences..., Pharmacology, Physiology, and Biological Chemistry Research; 93.862, Genetics and Developmental Biology...

75 FR 14565 - NIST Summer Institute for Middle School Science Teachers; Availability of Funds

Science.gov (United States)

2010-03-26

... areas of science, technology, engineering and mathematics (STEM) at the middle school level (grades 6-8... encourage them to inspire students to pursue careers in STEM fields. DATES: Proposals must be received at... educational institutions that are teaching students in the areas of Science, Technology, Engineering and...

Developing your Career in an Age of Team-Science

Science.gov (United States)

Zucker, Deborah

2013-01-01

Academic institutions and researchers are becoming increasingly involved in translational research to spur innovation in addressing many complex biomedical and societal problems, and in response to the focus of the NIH and other funders. One approach to translational research is to development interdisciplinary research teams. By bringing together collaborators with diverse research backgrounds and perspectives, these teams seek to blend their science and the workings of the scientists to push beyond the limits of current research. While team-science promises individual and team benefits in creating and implementing innovations, its increased complexity poses challenges. In particular, since academic career advancement commonly focuses on individual achievement, team-science might differentially impact early stage researchers. This need to be recognized for individual accomplishments in order to move forward in an academic career may give rise to research-team conflicts. Raising awareness to career-related aspects of team science will help individuals (particularly trainees and junior faculty) take steps to align their excitement and participation with the success of both the team and their personal career advancement. PMID:22525235

Lecture 10: The European Bioinformatics Institute - "Big data" for biomedical sciences

CERN Multimedia

CERN. Geneva; Dana, Jose

2013-01-01

Part 1: Big data for biomedical sciences (Tom Hancocks) Ten years ago witnessed the completion of the first international 'Big Biology' project that sequenced the human genome. In the years since biological sciences, have seen a vast growth in data. In the coming years advances will come from integration of experimental approaches and the translation into applied technologies is the hospital, clinic and even at home. This talk will examine the development of infrastructure, physical and virtual, that will allow millions of life scientists across Europe better access to biological data Tom studied Human Genetics at the University of Leeds and McMaster University, before completing an MSc in Analytical Genomics at the University of Birmingham. He has worked for the UK National Health Service in diagnostic genetics and in training healthcare scientists and clinicians in bioinformatics. Tom joined the EBI in 2012 and is responsible for the scientific development and delivery of training for the BioMedBridges pr...

75 FR 5771 - Institute of Education Sciences; Overview Information; Education Research and Special Education...

Science.gov (United States)

2010-02-04

... DEPARTMENT OF EDUCATION Institute of Education Sciences; Overview Information; Education Research and Special Education Research Grant Programs; Notice Inviting Applications for New Awards for Fiscal....305D, 84.305E, 84.324A, 84.324B, and 84.324C. Summary: The Director of the Institute of Education...

Translational Research for Occupational Therapy: Using SPRE in Hippotherapy for Children with Developmental Disabilities.

Science.gov (United States)

Weissman-Miller, Deborah; Miller, Rosalie J; Shotwell, Mary P

2017-01-01

Translational research is redefined in this paper using a combination of methods in statistics and data science to enhance the understanding of outcomes and practice in occupational therapy. These new methods are applied, using larger data and smaller single-subject data, to a study in hippotherapy for children with developmental disabilities (DD). The Centers for Disease Control and Prevention estimates DD affects nearly 10 million children, aged 2-19, where diagnoses may be comorbid. Hippotherapy is defined here as a treatment strategy in occupational therapy using equine movement to achieve functional outcomes. Semiparametric ratio estimator (SPRE), a single-subject statistical and small data science model, is used to derive a "change point" indicating where the participant adapts to treatment, from which predictions are made. Data analyzed here is from an institutional review board approved pilot study using the Hippotherapy Evaluation and Assessment Tool measure, where outcomes are given separately for each of four measured domains and the total scores of each participant. Analysis with SPRE, using statistical methods to predict a "change point" and data science graphical interpretations of data, shows the translational comparisons between results from larger mean values and the very different results from smaller values for each HEAT domain in terms of relationships and statistical probabilities.

Translational Research for Occupational Therapy: Using SPRE in Hippotherapy for Children with Developmental Disabilities

Science.gov (United States)

Miller, Rosalie J.; Shotwell, Mary P.

2017-01-01

Translational research is redefined in this paper using a combination of methods in statistics and data science to enhance the understanding of outcomes and practice in occupational therapy. These new methods are applied, using larger data and smaller single-subject data, to a study in hippotherapy for children with developmental disabilities (DD). The Centers for Disease Control and Prevention estimates DD affects nearly 10 million children, aged 2–19, where diagnoses may be comorbid. Hippotherapy is defined here as a treatment strategy in occupational therapy using equine movement to achieve functional outcomes. Semiparametric ratio estimator (SPRE), a single-subject statistical and small data science model, is used to derive a “change point” indicating where the participant adapts to treatment, from which predictions are made. Data analyzed here is from an institutional review board approved pilot study using the Hippotherapy Evaluation and Assessment Tool measure, where outcomes are given separately for each of four measured domains and the total scores of each participant. Analysis with SPRE, using statistical methods to predict a “change point” and data science graphical interpretations of data, shows the translational comparisons between results from larger mean values and the very different results from smaller values for each HEAT domain in terms of relationships and statistical probabilities. PMID:29097962

Translational Research for Occupational Therapy: Using SPRE in Hippotherapy for Children with Developmental Disabilities

Directory of Open Access Journals (Sweden)

Deborah Weissman-Miller

2017-01-01

Full Text Available Translational research is redefined in this paper using a combination of methods in statistics and data science to enhance the understanding of outcomes and practice in occupational therapy. These new methods are applied, using larger data and smaller single-subject data, to a study in hippotherapy for children with developmental disabilities (DD. The Centers for Disease Control and Prevention estimates DD affects nearly 10 million children, aged 2–19, where diagnoses may be comorbid. Hippotherapy is defined here as a treatment strategy in occupational therapy using equine movement to achieve functional outcomes. Semiparametric ratio estimator (SPRE, a single-subject statistical and small data science model, is used to derive a “change point” indicating where the participant adapts to treatment, from which predictions are made. Data analyzed here is from an institutional review board approved pilot study using the Hippotherapy Evaluation and Assessment Tool measure, where outcomes are given separately for each of four measured domains and the total scores of each participant. Analysis with SPRE, using statistical methods to predict a “change point” and data science graphical interpretations of data, shows the translational comparisons between results from larger mean values and the very different results from smaller values for each HEAT domain in terms of relationships and statistical probabilities.

Institute of Biochemistry and Biophysics. Research Report 1996-1997

International Nuclear Information System (INIS)

1998-01-01

Scientific interests of the Institute of Biochemistry and Biophysics of the Polish Academy of Sciences have evolved from classical biochemistry, biophysics and physiological chemistry to up-to-date molecular biology. Research interests are focussed on replication, mutagenesis and repair of DNA; regulation of gene expression at various levels; biosynthesis and post-translational modifications of proteins; gene sequencing and functional analysis of open reading frames; structure, function and regulation of enzymes; conformation of proteins and peptides; modelling of structures and prediction of functions of proteins; mechanisms of electron transfer in polypeptides

Institute of Biochemistry and Biophysics. Research Report 1996-1997

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-07-01

Scientific interests of the Institute of Biochemistry and Biophysics of the Polish Academy of Sciences have evolved from classical biochemistry, biophysics and physiological chemistry to up-to-date molecular biology. Research interests are focussed on replication, mutagenesis and repair of DNA; regulation of gene expression at various levels; biosynthesis and post-translational modifications of proteins; gene sequencing and functional analysis of open reading frames; structure, function and regulation of enzymes; conformation of proteins and peptides; modelling of structures and prediction of functions of proteins; mechanisms of electron transfer in polypeptides.

Potential Ambiguity Translation Performances within Legal Language Institutional Nomenclature

Directory of Open Access Journals (Sweden)

Oţăt Diana

2015-12-01

Full Text Available Motivated by a paradoxical corollary of ambiguities in legal documents and especially in contract texts, the current paper underpins a dichotomy approach to unintended ambiguities aiming to establish a referential framework for the occurrence rate of translation ambiguities within the legal language nomenclature. The research focus is on a twofold situation since ambiguities may. on the one hand, arise dining the translation process, generated by the translator’s lack of competence, i.e. inadequate use of English regarding the special nature of legal language, or. on the other hand, they may be simply transferred from the source language into the target language without even noticing the potential ambiguous situation, i.e. culture-bound ambiguities. Hence, the paper proposes a contrastive analysis in order to localize the occurrence of lexical, structural, and socio-cultural ambiguities triggered by the use of the term performance and its Romanian equivalents in a number of sales contracts.

Precise machine translation of computer science study

CSIR Research Space (South Africa)

Marais, L

2015-07-01

Full Text Available mobile (Android) application for translating discrete mathematics definitions between English and Afrikaans. The main component of the system is a Grammatical Framework (GF) application grammar which produces syntactically and semantically accurate...

Core competencies in the science and practice of knowledge translation: description of a Canadian strategic training initiative.

Science.gov (United States)

Straus, Sharon E; Brouwers, Melissa; Johnson, David; Lavis, John N; Légaré, France; Majumdar, Sumit R; McKibbon, K Ann; Sales, Anne E; Stacey, Dawn; Klein, Gail; Grimshaw, Jeremy

2011-12-09

Globally, healthcare systems are attempting to optimize quality of care. This challenge has resulted in the development of implementation science or knowledge translation (KT) and the resulting need to build capacity in both the science and practice of KT. We are attempting to meet these challenges through the creation of a national training initiative in KT. We have identified core competencies in this field and have developed a series of educational courses and materials for three training streams. We report the outline for this approach and the progress to date. We have prepared a strategy to develop, implement, and evaluate a national training initiative to build capacity in the science and practice of KT. Ultimately through this initiative, we hope to meet the capacity demand for KT researchers and practitioners in Canada that will lead to improved care and a strengthened healthcare system.

Annual report of National Institute for Fusion Science. April 2011 - March 2012

International Nuclear Information System (INIS)

2012-01-01

This annual report summarizes the research activities at NIFS (the National Institute for Fusion Science) between April 2011 and March 2012. NIFS is pursuing the integration of science and technology to realize a fusion power plant. The systematization of plasma physics, and research and development of reactor relevant engineering are key elements in our strategy. NIFS has been exploiting its role as an inter-university research organization and executing a variety of excellent collaborating studies together with universities and research institutes abroad as well as in Japan. The major projects of NIFS are the Large Helical Device (LHD) Project, the Numerical Simulation Research Project, the Fusion Engineering Research Project and the Coordination Research Project. These major projects are accompanied by unique supporting research. Advanced engineering and fusion reactor design studies are strongly promoted. (J.P.N.)

Annual report of National Institute for Fusion Science. April 2009 - March 2010

International Nuclear Information System (INIS)

2010-01-01

This annual report summarizes the research activities at NIFS (the National Institute for Fusion Science) between April 2009 and March 2010. NIFS is pursuing the integration of science and technology to realize a fusion power plant. The systematization of plasma physics, and research and development of reactor relevant engineering are key elements in our strategy. NIFS has been exploiting its role as an inter-university research organization and executing a variety of excellent collaborating studies together with universities and research institutes abroad as well as in Japan. The major projects of NIFS are the Large Helical Device (LHD) Project, the Numerical Simulation Research Project, the Fusion Engineering Research Project and the Coordination Research Project. These major projects are accompanied by unique supporting research. Advanced engineering and fusion reactor design studies are strongly promoted. (J.P.N.)

Annual report of National Institute for Fusion Science. April 2012 - March 2013

International Nuclear Information System (INIS)

2013-01-01

This annual report summarizes the research activities at NIFS (the National Institute for Fusion Science) between April 2012 and March 2013. NIFS is pursuing the integration of science and technology to realize a fusion power plant. The systematization of plasma physics, and research and development of reactor relevant engineering are key elements in our strategy. NIFS has been exploiting its role as an inter-university research organization and executing a variety of excellent collaborating studies together with universities and research institutes abroad as well as in Japan. The major projects of NIFS are the Large Helical Device (LHD) Project, the Numerical Simulation Research Project, the Fusion Engineering Research Project and the Coordination Research Project. These major projects are accompanied by unique supporting research. Advanced engineering and fusion reactor design studies are strongly promoted. (J.P.N.)

Translational nanomedicine: status assessment and opportunities.

Science.gov (United States)

Murday, James S; Siegel, Richard W; Stein, Judith; Wright, J Fraser

2009-09-01

Nano-enabled technologies hold great promise for medicine and health. The rapid progress by the physical sciences/engineering communities in synthesizing nanostructures and characterizing their properties must be rapidly exploited in medicine and health toward reducing mortality rate, morbidity an illness imposes on a patient, disease prevalence, and general societal burden. A National Science Foundation-funded workshop, "Re-Engineering Basic and Clinical Research to Catalyze Translational Nanoscience," was held 16-19 March 2008 at the University of Southern California. Based on that workshop and literature review, this article briefly explores scientific, economic, and societal drivers for nanomedicine initiatives; examines the science, engineering, and medical research needs; succinctly reviews the US federal investment directly germane to medicine and health, with brief mention of the European Union (EU) effort; and presents recommendations to accelerate the translation of nano-enabled technologies from laboratory discovery into clinical practice. An excellent review paper based on the NSF funded workshop "Re-Engineering Basic and Clinical Research to Catalyze Translational Nanoscience" (16-19 March 2008) and extensive literature search, this paper briefly explores the current state and future perspectives of nanomedicine.

Activities of the Research Institute for Advanced Computer Science

Science.gov (United States)

Oliger, Joseph

1994-01-01

The Research Institute for Advanced Computer Science (RIACS) was established by the Universities Space Research Association (USRA) at the NASA Ames Research Center (ARC) on June 6, 1983. RIACS is privately operated by USRA, a consortium of universities with research programs in the aerospace sciences, under contract with NASA. The primary mission of RIACS is to provide research and expertise in computer science and scientific computing to support the scientific missions of NASA ARC. The research carried out at RIACS must change its emphasis from year to year in response to NASA ARC's changing needs and technological opportunities. Research at RIACS is currently being done in the following areas: (1) parallel computing; (2) advanced methods for scientific computing; (3) high performance networks; and (4) learning systems. RIACS technical reports are usually preprints of manuscripts that have been submitted to research journals or conference proceedings. A list of these reports for the period January 1, 1994 through December 31, 1994 is in the Reports and Abstracts section of this report.

Understanding the performance and impact of public knowledge translation funding interventions: protocol for an evaluation of Canadian Institutes of Health Research knowledge translation funding programs.

Science.gov (United States)

McLean, Robert K D; Graham, Ian D; Bosompra, Kwadwo; Choudhry, Yumna; Coen, Stephanie E; Macleod, Martha; Manuel, Christopher; McCarthy, Ryan; Mota, Adrian; Peckham, David; Tetroe, Jacqueline M; Tucker, Joanne

2012-06-22

The Canadian Institutes of Health Research (CIHR) has defined knowledge translation (KT) as a dynamic and iterative process that includes the synthesis, dissemination, exchange, and ethically-sound application of knowledge to improve the health of Canadians, provide more effective health services and products, and strengthen the healthcare system. CIHR, the national health research funding agency in Canada, has undertaken to advance this concept through direct research funding opportunities in KT. Because CIHR is recognized within Canada and internationally for leading and funding the advancement of KT science and practice, it is essential and timely to evaluate this intervention, and specifically, these funding opportunities. The study will employ a novel method of participatory, utilization-focused evaluation inspired by the principles of integrated KT. It will use a mixed methods approach, drawing on both quantitative and qualitative data, and will elicit participation from CIHR funded researchers, knowledge users, KT experts, as well as other health research funding agencies. Lines of inquiry will include an international environmental scan, document/data reviews, in-depth interviews, targeted surveys, case studies, and an expert review panel. The study will investigate how efficiently and effectively the CIHR model of KT funding programs operates, what immediate outcomes these funding mechanisms have produced, and what impact these programs have had on the broader state of health research, health research uptake, and health improvement. The protocol and results of this evaluation will be of interest to those engaged in the theory, practice, and evaluation of KT. The dissemination of the study protocol and results to both practitioners and theorists will help to fill a gap in knowledge in three areas: the role of a public research funding agency in facilitating KT, the outcomes and impacts KT funding interventions, and how KT can best be evaluated.

Livestock models in translational medicine.

Science.gov (United States)

Roth, James A; Tuggle, Christopher K

2015-01-01

This issue of the ILAR Journal focuses on livestock models in translational medicine. Livestock models of selected human diseases present important advantages as compared with rodent models for translating fundamental breakthroughs in biology to useful preventatives and therapeutics for humans. Livestock reflect the complexity of applying medical advances in an outbred species. In many cases, the pathogenesis of infectious, metabolic, genetic, and neoplastic diseases in livestock species more closely resembles that in humans than does the pathogenesis of rodent models. Livestock models also provide the advantage of similar organ size and function and the ability to serially sample an animal throughout the study period. Research using livestock models for human disease often benefits not only human health but animal health and food production as well. This issue of the ILAR Journal presents information on translational research using livestock models in two broad areas: microbiology and infectious disease (transmissible spongiform encephalopathies, mycobacterial infections, influenza A virus infection, vaccine development and testing, the human microbiota) and metabolic, neoplastic, and genetic disorders (stem cell therapy, male germ line cell biology, pulmonary adenocarcinoma, muscular dystrophy, wound healing). In addition, there is a manuscript devoted to Institutional Animal Care and Use Committees' responsibilities for reviewing research using livestock models. Conducting translational research using livestock models requires special facilities and researchers with expertise in livestock. There are many institutions in the world with experienced researchers and facilities designed for livestock research; primarily associated with colleges of agriculture and veterinary medicine or government laboratories. © The Author 2015. Published by Oxford University Press on behalf of the Institute for Laboratory Animal Research. All rights reserved. For permissions

Effective knowledge management in translational medicine.

Science.gov (United States)

Szalma, Sándor; Koka, Venkata; Khasanova, Tatiana; Perakslis, Eric D

2010-07-19

The growing consensus that most valuable data source for biomedical discoveries is derived from human samples is clearly reflected in the growing number of translational medicine and translational sciences departments across pharma as well as academic and government supported initiatives such as Clinical and Translational Science Awards (CTSA) in the US and the Seventh Framework Programme (FP7) of EU with emphasis on translating research for human health. The pharmaceutical companies of Johnson and Johnson have established translational and biomarker departments and implemented an effective knowledge management framework including building a data warehouse and the associated data mining applications. The implemented resource is built from open source systems such as i2b2 and GenePattern. The system has been deployed across multiple therapeutic areas within the pharmaceutical companies of Johnson and Johnsons and being used actively to integrate and mine internal and public data to support drug discovery and development decisions such as indication selection and trial design in a translational medicine setting. Our results show that the established system allows scientist to quickly re-validate hypotheses or generate new ones with the use of an intuitive graphical interface. The implemented resource can serve as the basis of precompetitive sharing and mining of studies involving samples from human subjects thus enhancing our understanding of human biology and pathophysiology and ultimately leading to more effective treatment of diseases which represent unmet medical needs.

Effective knowledge management in translational medicine

Directory of Open Access Journals (Sweden)

Khasanova Tatiana

2010-07-01

Full Text Available Abstract Background The growing consensus that most valuable data source for biomedical discoveries is derived from human samples is clearly reflected in the growing number of translational medicine and translational sciences departments across pharma as well as academic and government supported initiatives such as Clinical and Translational Science Awards (CTSA in the US and the Seventh Framework Programme (FP7 of EU with emphasis on translating research for human health. Methods The pharmaceutical companies of Johnson and Johnson have established translational and biomarker departments and implemented an effective knowledge management framework including building a data warehouse and the associated data mining applications. The implemented resource is built from open source systems such as i2b2 and GenePattern. Results The system has been deployed across multiple therapeutic areas within the pharmaceutical companies of Johnson and Johnsons and being used actively to integrate and mine internal and public data to support drug discovery and development decisions such as indication selection and trial design in a translational medicine setting. Our results show that the established system allows scientist to quickly re-validate hypotheses or generate new ones with the use of an intuitive graphical interface. Conclusions The implemented resource can serve as the basis of precompetitive sharing and mining of studies involving samples from human subjects thus enhancing our understanding of human biology and pathophysiology and ultimately leading to more effective treatment of diseases which represent unmet medical needs.

Nuclear and Energy Research Institute (1956-2000). A case study under the science, technology and brazilian culture history

International Nuclear Information System (INIS)

Gordon, Ana Maria Pinho Leite

2003-01-01

We analysed a period of the contemporary Brazilian history with the aim to discuss the inter-relationship between science, technology (S and T) and culture in a developing country, showing as a background for a case of study the history of the 'Instituto de Pesquisas Energeticas e Nucleares'. The history of Science and Technology, as a result of the human brain ability of innovate using the resources offered by nature, it is not only the description of successive findings carried out by talented men. It is a reflex of determined age of history as a consequence of accumulated knowledge connected also to human and cultural relationships, which together leads to the scientific and technological progress. In fact, the human brain and society march along together and can not be separated in this journey. In our study we recovered the initial steps of IPEN's outbreak; inserted its achievements in the context of the national policy for nuclear technology and evaluated how this policy was a reply of the governmental organizations to the worldwide situation. Finally, we spread the scientific ideas and technological findings of this institution, who has translate much of the life style and culture of our society. For this purposes, we analysed internal technical report series elaborated by several researchers and few testimonies. The Institution developed the fuel cycle technology, supplied radioisotopes for medical diagnosis and treatment purposes, generating economic resources for our country. The nuclear techniques are a relevant tool for researchers of this Institution applied for several purposes, including the assessment of the radioactivity levels in the environment, radioprotection, etc. Besides those applications, other techniques including the laser technology, the fuel cell, corrosion studies, etc, were implemented as a result of the improved capabilities and skills acquired during the almost 50 years of the Institute's existence. We make evident two strong

COLLABORATING WITH THE COMMUNITY: THE EXTRA-TERRITORIAL TRANSLATIONAL RESEARCH TEAM.

Science.gov (United States)

Kotarba, Joseph A; Croisant, Sharon A; Elferink, Cornelis; Scott, Lauren E

2014-12-05

The purpose of the present study is to suggest a revision of the team science concept to the more inclusive extra-territorial research team (ETRT). Translational thinking is largely marked by the perception of the team as a thing-like structure at the center of the scientific activity. Collaboration accordingly involves bringing external others (e.g., scientists, community members, and clinicians) into the team through limited or dependent participation. We suggest that a promising and innovative way to see the team is as an idea : a schema for assembling and managing relationships among otherwise disparate individuals with vested interests in the problem at hand. Thus, the ETRT can be seen as a process as well as an object . We provide a case study derived from a qualitative analysis of the impact of the logic of translational science on a team assessment of environmental health following an off-coast oil disaster. The ETRT in question displayed the following principles of constructive relationship management: a high sense of adventure given the quick pace and timeliness given the relevance of the oil spill to all team members; regular meetings in the community to avoid the appearance of academic hegemony; open access by lay as well as institutional scientists; integration of emergency management coordinators into the group; and the languages of public health, environmental pharmacology/toxicology and coastal culture seamlessly interwoven in discussion. The ETRT model is an appropriate strategy for mobilizing and integrating the knowledge and skills needed for comprehensive science and service responses, especially during crisis.

Model for bridging the translational "valleys of death" in spinal cord injury research

Directory of Open Access Journals (Sweden)

Barrable B

2014-04-01

Full Text Available Bill Barrable,1 Nancy Thorogood,1 Vanessa Noonan,1,2 Jocelyn Tomkinson,1 Phalgun Joshi,1 Ken Stephenson,1 John Barclay,1 Katharina Kovacs Burns3 1Rick Hansen Institute, 2Division of Spine, Department of Orthopaedics, University of British Columbia, Vancouver, BC, 3Health Sciences Council, University of Alberta, Edmonton, AB, Canada Abstract: To improve health care outcomes with cost-effective treatments and prevention initiatives, basic health research must be translated into clinical application and studied during implementation, a process commonly referred to as translational research. It is estimated that only 14% of health-related scientific discoveries enter into medical practice and that it takes an average of 17 years for them to do so. The transition from basic research to clinical knowledge and from clinical knowledge to practice or implementation is so fraught with obstacles that these transitions are often referred to as “valleys of death”. The Rick Hansen Institute has developed a unique praxis model for translational research in the field of spinal cord injury (SCI. The praxis model involves three components. The first is a coordinated program strategy of cure, care, consumer engagement, and commercialization. The second is a knowledge cycle that consists of four phases, ie, environmental scanning, knowledge generation and synthesis, knowledge validation, and implementation. The third is the provision of relevant resources and infrastructure to overcome obstacles in the “valleys of death”, ie, funding, clinical research operations, informatics, clinical research and best practice implementation, consumer engagement, collaborative networks, and strategic partnerships. This model, which is to be independently evaluated in 2018 to determine its strengths and limitations, has been used to advance treatments for pressure ulcers in SCI. The Rick Hansen Institute has developed an innovative solution to move knowledge into action by

Transparency and translation of science in a modern world.

Science.gov (United States)

Grandjean, Philippe; Ozonoff, David

2013-08-27

The co-Editors-in-Chief of Environmental Health respond to an unusual initiative taken by editors of 14 toxicology journals to influence pending decisions by the European Commission to establish a framework for regulating chemicals that pose a hazard to normal function of the endocrine system. This initiative is also the subject of this Commentary in this journal by authors who recently reviewed the subject and who point out inaccuracies in the toxicology editors' critique. The dispute is about potential public policy development, rather than on science translation and research opportunities and priorities. The toxicology journal editors recommend that chemicals be examined in depth one by one, ignoring modern achievements in biomedical research that would allow new understanding of the effects of classes of toxic substances in complex biological systems. Concerns about policy positions framed as scientific ones are especially important in a time with shrinking public support for biomedical research affects priorities. In such a setting, conflict of interest declarations are important, especially in research publications that address issues of public concern and where financial and other interests may play a role. Science relies on trust, and reasonable disclosure of financial or other potential conflicts is therefore essential. This need has been emphasized by recent discoveries of hidden financial conflicts in publications in toxicology journals, thus misleading readers and the public about the safety of particular industrial products. The transparency provided by Environmental Health includes open access and open peer review, with reader access to reviews, including the identity of reviewers and their statements on possible conflicts of interest. However, the editors of the 14 toxicology journals did not provide any information on potential conflicts of interest, an oversight that needs to be corrected.

[The role of Hunayn, physician and translator].

Science.gov (United States)

Habbi, J

1994-01-01

Hunayn ibn Ishāq is one of the most important translators of scientific and medical texts in the 'abbāsid era. He played a fundamental role in the transmission of Greek medical science to the Arab world, because of his deep knowledge of the Syriac, Arabic and Persian languages. He translated about 300 texts, especially medical ones, and he founded a school in which many disciples were instructed in the art of translation, like his son Ishāq and his nephew Hubays. Hunayn composed a lexicon of scientific terminology, using a new method of translation which represents his great innovation.

Science self-efficacy of African Americans enrolled in freshman level physical science courses in two historically black institutions

Science.gov (United States)

Prihoda, Belinda Ann

2011-12-01

Science education must be a priority for citizens to function and be productive in a global, technological society. African Americans receive fewer science degrees in proportion to the Caucasian population. The primary purposes of this study were to determine the difference between the pretest and posttest science self-efficacy scores of African-American nonscience majors, the difference between the pretest and posttest science self-efficacy scores of African-American science majors, the relationship between science self-efficacy and course grade, the relationship between gender and science self-efficacy score, and the relationship between science self-efficacy score and course withdrawal. This study utilized a Likert survey instrument. All participants were enrolled in freshman level courses in the physical sciences at a historically black institution: a college or university. Participants completed the pretest survey within two weeks after the 12th class day of the semester. Initially, 458 participants completed the pretest survey. The posttest was administered within two weeks before the final exam. Only 245 participants completed the posttest survey. Results indicate that there is a difference in science self-efficacy of science majors and nonscience majors. There was no significant difference between the pretest and posttest science self-efficacy scores of African-American science majors and nonscience majors. There was no significant relationship between science self-efficacy and course grade, gender and science self-efficacy score, and course withdrawal and science self-efficacy score.

Core competencies in the science and practice of knowledge translation: description of a Canadian strategic training initiative

Directory of Open Access Journals (Sweden)

Straus Sharon E

2011-12-01

Full Text Available Abstract Background Globally, healthcare systems are attempting to optimize quality of care. This challenge has resulted in the development of implementation science or knowledge translation (KT and the resulting need to build capacity in both the science and practice of KT. Findings We are attempting to meet these challenges through the creation of a national training initiative in KT. We have identified core competencies in this field and have developed a series of educational courses and materials for three training streams. We report the outline for this approach and the progress to date. Conclusions We have prepared a strategy to develop, implement, and evaluate a national training initiative to build capacity in the science and practice of KT. Ultimately through this initiative, we hope to meet the capacity demand for KT researchers and practitioners in Canada that will lead to improved care and a strengthened healthcare system.

Central Scientific and Research Institute of Nuclear Information as the branch centre of information on nuclear science and engineering

International Nuclear Information System (INIS)

Arkhangel'skij, I.A.; Sokolov, D.D.; Kalinin, V.F.; Nikiforov, V.S.

1982-01-01

The main tasks are considered in the scope of the Central Scientific-Research Institute for Information and Technological and Economic Studies on Nuclear Science and Technology. (TsNIIAtominform). The institute coordinates scientific research and information activity of information agencies of all the USSR organizations engaged in nuclear science and technology, excercises a centralized completion of their libraries, develops and puts into practice the most progressive methods for the information servicing. The institute is a national INIS center of the USSR. Here a system for the automatic information dissemination has been successfully elaborated and employed. Much of the institute activity is given to the estimation and analysis of information and to the determination of tendencies in the nuclear science and technology development. A conclusion is drawn to the effect that TsNIIAtominform, within 15 years of its existence, has formed as a center ensuring functioning of the system of scientific and technical information on nuclear science and technology

Science on the net: an analysis of the websites of the European public research institutions

Directory of Open Access Journals (Sweden)

Laura Massoli

2007-09-01

Full Text Available This article introduces a study on the websites of several European public research institutions that aims at identifying the science communication model chosen and implemented online with the purpose of reaching different target publics. The analytical approach takes into account a number of indicators: from the institutional identity to the scientific features, from the interactive services to the internationalisation level, in order to evaluate whether the web provides an added value in the adopted communication model and in building a relation with the users. Lights and shades emerge from this study in which good practices side examples of a much weaker science communication approach, outlining a general context where a public research institution website has been still used as a presentation tool and its interactive opportunities have not been capitalised.

Knowledge of healthy foods does not translate to healthy snack consumption among exercise science undergraduates.

Science.gov (United States)

McArthur, Laura H; Valentino, Antonette; Holbert, Donald

2017-06-01

This cross-sectional survey study compared the on- and off-campus snack choices and related correlates of convenience samples of exercise science (ES) ( n = 165, M = 45%, F = 55%) and non-exercise science (NES) ( n =160, M = 43%, F = 57%) undergraduates. The hypothesis posed was that knowledge of healthy foods will not translate to healthier snack consumption by the ES students, and that the snack choices and related correlates of ES and NES students will be similar. Data were collected using self-administered questionnaires completed in classrooms (ES sample) and at high-traffic locations on-campus (NES sample). Chi-square and t-test analyses compared ES and NES students on snack correlates. Snacks consumed most often by the ES and NES students on-campus were health bars/squares ( n = 56 vs. n = 48) and savory snacks ( n = 55 vs. n = 71), and off-campus were savory snacks ( n = 60 vs. n = 71) and fruits ( n = 41 vs. n = 34). Over half of both samples believed their snack choices were a mix of unhealthy and healthy. Fruits were considered healthier snacks and chips less healthy by both samples, and fruits were the most often recommended snack. About 20% believed these choices would impact their health unfavorably, and about two thirds self-classified in the action stages for healthy snacking. Since knowledge about healthy food choices did not translate to healthy snack selection, these students would benefit from interventions that teach selection and preparation of healthy snacks on a restricted budget.

Towards Strategic Actorhood? The Execution of Institutional Positioning Strategies at Finnish Universities of Applied Sciences

Science.gov (United States)

Vuori, Johanna

2016-01-01

Given the emerging interest in institutional positioning and to augment the small number of empirical studies in this field, this paper presents discussion about how Finnish universities of applied sciences implement their profiling strategies. The analysis is based on an examination of documents recently submitted by these institutions when…

"Wow! Look at That!": Discourse as a Means to Improve Teachers' Science Content Learning in Informal Science Institutions

Science.gov (United States)

Holliday, Gary M.; Lederman, Judith S.; Lederman, Norman G.

2014-01-01

Currently, it is not clear whether professional development staff at Informal Science Institutions (ISIs) are considering the way exhibits contribute to the social aspects of learning as described by the contextual model of learning (CML) (Falk & Dierking in "The museum experience." Whalesback, Washington, 1992; "Learning from…

The media of sociology: tight or loose translations?

Science.gov (United States)

Guggenheim, Michael

2015-06-01

Sociologists have increasingly come to recognize that the discipline has unduly privileged textual representations, but efforts to incorporate visual and other media are still only in their beginning. This paper develops an analysis of the ways objects of knowledge are translated into other media, in order to understand the visual practices of sociology and to point out unused possibilities. I argue that the discourse on visual sociology, by assuming that photographs are less objective than text, is based on an asymmetric media-determinism and on a misleading notion of objectivity. Instead, I suggest to analyse media with the concept of translations. I introduce several kinds of translations, most centrally the distinction between tight and loose ones. I show that many sciences, such as biology, focus on tight translations, using a variety of media and manipulating both research objects and representations. Sociology, in contrast, uses both tight and loose translations, but uses the latter only for texts. For visuals, sociology restricts itself to what I call 'the documentary': focusing on mechanical recording technologies without manipulating either the object of research or the representation. I conclude by discussing three rare examples of what is largely excluded in sociology: visual loose translations, visual tight translations based on non-mechanical recording technologies, and visual tight translations based on mechanical recording technologies that include the manipulation of both object and representation. © London School of Economics and Political Science 2015.

Annual report of Nuclear Science Research Institute, JFY2005

International Nuclear Information System (INIS)

2007-04-01

Japan Atomic Energy Agency (JAEA) was inaugurated on October 1st, 2005. Works for the operation and maintenance of various research facilities as well as safety management, radiation protection, and radioactive wastes management, which have been undertaken by departments in Tokai Research Establishment of Japan Atomic Energy Research Institute (JAERI), were inherited by newly established departments of Nuclear Science Research Institute (NSRI). The NSRI is composed of Planning and Coordination Office and seven departments such as Department of Operational Safety Administration, Department of Radiation Protection, Department of Research Reactor and Tandem Accelerator, Department of Hot Laboratories and Facilities, Department of Criticality and Fuel Cycle Research Facilities, Department of Decommissioning and Waste Management, and Engineering Services Department. This annual report of JFY 2005 summarizes the activities of NSRI and is expected to be referred to and utilized by R and D departments and project promotion sectors at NSRI site for the enhancement of their own research and management activities to attain their goals according to Middle-term Plan' successfully and effectively. In chapter 1, outline of organization and administrative activities of NSRI is described. In chapter 2, the following activities made by the departments in NSRI are summarized, i.e., (1) operation and maintenance of research reactors (JRR-3, JRR-4, NSRR), criticality assemblies (STACY, TRACY, FCA, TCA), hot laboratories, (BECKY, Reactor Fuel Examination Facility, WASTEF, Research Laboratory 4, Plutonium Research Laboratory 1, Tokai Hot Laboratory, etc), and large-scale facilities (Tandem accelerator, LSTF, THYNC, TPTF, etc), and (2) safety management, radiation protection, management of radioactive wastes, decommissioning of nuclear facilities, engineering services, utilities and maintenance, etc, all of which are indispensable for the stable and safe operation and utilization of the

Development of atomic spectroscopy methods in geological institutes of Faculty of Natural Sciences Comenius University and Slovak Academy of Science

International Nuclear Information System (INIS)

Medved, E.

1998-01-01

Development of atomic spectrochemistry methods in Geological Institute of Faculty of Natural Sciences, Comenius University (GI FNS CU) is connected with its establishment in 1957. Its instrumental equipment and location resulted from the already existing Laboratory in the Chair for Mineralogy and Crystallography of FNS CU. In Geological Institute of Slovak Academy of Science (GI SAS) the development of atomic spectroscopy methods started later, only since 1963, when the Member of Academy, Prof. RNDr. B. Cambel, DrSc. became its director. In both institutes the methods of atomic emission spectrography were used as first. A new quality in the development started since 1969 when the Institutes moved to common buildings in Petrzalka (Bratislava), the first atomic absorption spectrometers were acquired and the Institutes were 'strengthened' by coming of Prof. Ing. E. Plsko, DrSc. In the following years the Institutes started to collaborate with some other organisations which were equipped with new facilities, e.g. in 1975 with X-ray fluorescence spectrometer, electron microprobe and in 1985 with inductively coupled plasma atomic emission spectrometer. This enabled to improve essentially the quality of research activities of both institutes in the chemical characterisation of geological materials, as well as in pedagogical work (students practice, diploma works and dissertations). In the present time characterized by new economic conditions a reduction of GI SAS laboratory activities has been realised. The laboratories of the GI FNS CU have, thanks to their director Ing. V. Stresko, PhD. shown also hence-forward a rich research, pedagogical and society activities what can be documented by numerous publications, citations, obtained awards, representations in professional societies and commissions, local and foreign advisory boards, accreditation boards etc. (author)

Aspen Global Change Institute Summer Science Sessions

Energy Technology Data Exchange (ETDEWEB)

Katzenberger, John; Kaye, Jack A

2006-10-01

The Aspen Global Change Institute (AGCI) successfully organized and convened six interdisciplinary meetings over the course of award NNG04GA21G. The topics of the meetings were consistent with a range of issues, goals and objectives as described within the NASA Earth Science Enterprise Strategic Plan and more broadly by the US Global Change Research Program/Our Changing Planet, the more recent Climate Change Program Strategic Plan and the NSF Pathways report. The meetings were chaired by two or more leaders from within the disciplinary focus of each session. 222 scholars for a total of 1097 participants-days were convened under the auspices of this award. The overall goal of each AGCI session is to further the understanding of Earth system science and global environmental change through interdisciplinary dialog. The format and structure of the meetings allows for presentation by each participant, in-depth discussion by the whole group, and smaller working group and synthesis activities. The size of the group is important in terms of the group dynamics and interaction, and the ability for each participant's work to be adequately presented and discussed within the duration of the meeting, while still allowing time for synthesis

ILLC-UvA translation system for EMNLP-WMT 2011

NARCIS (Netherlands)

Khalilov, M.; Sima'an, K.

2011-01-01

In this paper we describe the Institute for Logic, Language and Computation (University of Amsterdam) phrase-based statistical machine translation system for Englishto- German translation proposed within the EMNLP-WMT 2011 shared task. The main novelty of the submitted system is a syntaxdriven

Bridging the Gap in Neurotherapeutic Discovery and Development: The Role of the National Institute of Neurological Disorders and Stroke in Translational Neuroscience.

Science.gov (United States)

Mott, Meghan; Koroshetz, Walter

2015-07-01

The mission of the National Institute of Neurological Disorders and Stroke (NINDS) is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease. NINDS supports early- and late-stage therapy development funding programs to accelerate preclinical discovery and the development of new therapeutic interventions for neurological disorders. The NINDS Office of Translational Research facilitates and funds the movement of discoveries from the laboratory to patients. Its grantees include academics, often with partnerships with the private sector, as well as small businesses, which, by Congressional mandate, receive > 3% of the NINDS budget for small business innovation research. This article provides an overview of NINDS-funded therapy development programs offered by the NINDS Office of Translational Research.

Annual report of National Institute of Radiological Sciences, April 1989 - March 1990

International Nuclear Information System (INIS)

1990-07-01

This annual report is a compilation of the research activities and achievement in the National Institute of Radiological Sciences (NIRS) in Japan during the fiscal year 1990 (from April 1989 through March 1990). Efforts at the NIRS are particularly aimed at three long term projects: 'risk due to low level radiation exposure to the general population', 'assessment of radiation exposure of the public to radioactivities as related to the environment', and 'food chain and medical use of accelerated heavy ions'. The research covers a wide range of radiological sciences from molecular to environmental studies and medicine including engineering. Topics consists of physics, chemistry, bio-medical science, clinical research, and environmental sciences, covering a total of 80 titles. A list of publications by staff members, activities of research divisions, and organization chart of the NIRS are given in Appendix. (N.K.)

Developing institutional collaboration between Wageningen University and the Chinese Academy of Agricultural Sciences

OpenAIRE

Bonnema, A.B.; Lin, Zhai; Qu, Liang; Jacobsen, E.

2006-01-01

Scientific co-operation between the Chinese Academy of Agricultural Sciences (CAAS) and Wageningen University (WU) has been underway since 1990, especially in the field of plant sciences. In 2001, CAAS and WU initiated a formal joint PhD training programme to further structure their co-operation. The goals of this co-operation are to: (1) initiate long-term institutional collaboration through capacity building; (2) jointly establish a modern laboratory; (3) jointly develop a cross-cultural sc...

FutureTox III: Bridges for Translation | Science Inventory | US ...

Science.gov (United States)

The present document describes key discussion points and outcomes of a Society of Toxicology (SOT) Contemporary Concepts in Toxicology (CCT) Workshop, entitled FutureTox III1,2 that was held in Crystal City, Virginia, November 19-20, 2015. The workshop built on the many lessons learned from the first 10 years of TT21 and the first two workshops in the FutureTox series (for summary of FutureTox II see (Knudsen et al., 2015); for summary of FutureTox I see (Rowlands et al., 2014)). FutureTox III was attended in person and via webcast by more than 300 scientists from government research and regulatory agencies, research institutes, academia, and the chemical and pharmaceutical industries in Europe, Canada, and the United States. The meeting materials for FutureTox III, currently available to meeting registrants at http://www.toxicology.org/events/shm/cct/meetings.asp#upcoming-pnl-open, will be open to the public on November 29, 2016. At this workshop, participants reviewed and discussed the state of the science in toxicology and human risk and exposure assessment with a focus on moving TT21 science into the arena of regulatory decision-making. This manuscript describes the outcome of the FutureTox III 'contemporary concepts in toxicology' conference of the Society Toxicology, held November 2015 in Crystal City VA.

Exploring the Potential of Corpus Use in Translation Training

DEFF Research Database (Denmark)

Laursen, Anne Lise; Pellón, Ismael Arinas

2014-01-01

translators only allows for teaching the students methods that they can apply systematically to several professional tasks. The chapter illustrates how the traditional translation training strategies can be combined with the use of concordancing software to cope with translations.......The chapter describes the corpus analysis strategies used with the translation master’s students at the Department of Business Communication at the Faculty of Business and Social Sciences (formerly Aarhus School of Business or ASB). The short time available for the training of specialized...

Translational educational research: a necessity for effective health-care improvement.

Science.gov (United States)

McGaghie, William C; Issenberg, S Barry; Cohen, Elaine R; Barsuk, Jeffrey H; Wayne, Diane B

2012-11-01

Medical education research contributes to translational science (TS) when its outcomes not only impact educational settings, but also downstream results, including better patient-care practices and improved patient outcomes. Simulation-based medical education (SBME) has demonstrated its role in achieving such distal results. Effective TS also encompasses implementation science, the science of health-care delivery. Educational, clinical, quality, and safety goals can only be achieved by thematic, sustained, and cumulative research programs, not isolated studies. Components of an SBME TS research program include motivated learners, curriculum grounded in evidence-based learning theory, educational resources, evaluation of downstream results, a productive research team, rigorous research methods, research resources, and health-care system acceptance and implementation. National research priorities are served from translational educational research. National funding priorities should endorse the contribution and value of translational education research.

Waste management in the Institute for Nuclear Sciences 'Vinca' - Belgrade

International Nuclear Information System (INIS)

Raicevic, J.; Avramovic, I.; Plecas, I.; Mandic, M.; Goldammer, W.

2004-01-01

The Vinca Institute of Nuclear Sciences served for many years as the only Yugoslav (Serbia and Montenegro) nuclear institute. Therefore, it acted for many years as national storage facility for the radioactive waste from all institutional (medical, military, etc.) activities. The interim storage was situated within the Vinca Institute historically at several different places. The main fraction of the wastes is stored in two metallic hangars. In addition, underground stainless steel tanks in concrete shields have been constructed to accept all processed liquid waste from the research reactor RA. The current situation of the interim storage facilities is not satisfactory. However, the principle limitation for improvements of the waste management at the Vinca Institute lies in the fact that long-term solutions cannot be addressed at the moment. Plans for a final repository for radioactive waste do not exist yet in the Serbia and Montenegro. Consequently, waste management can only address an interim solution. In order to conduct all waste management activities in a safe manner, an overall strategy and study for improvement/rearrangement of radioactive waste storage facilities was developed which addresses all wastes and their management. The IAEA is providing assistance to these activities. This support includes a project which has been initiated by the IAEA to improve the waste management at the Vinca Institute. This paper describes the current status of the development of this overall strategy and study for improvement/rearrangement of radioactive waste storage facilities. The information available and the current status of the development of concepts for the processing and storage of the waste are summarised. (author)

Annual report of National Institute of Radiological Sciences, 2001

International Nuclear Information System (INIS)

2002-10-01

From this year, National Institute of Radiological Sciences (NIRS) started as an administrative corporation independent of the Government and concomitant internal re-organization was conducted: Three major Centers for Radiation safety, Radiation Emergency Medicine and Charged Particle Therapy were made. This report contains the summary of NIRS activities; research and development including studies of important project, fundamental research, fundamental and frontier research, contract research and fact-finding; management; organization/budget/finance; and appendix. Important projects are radiological studies in advanced medicine, on sensitivity, of effects on human and of hazard. Fundamental research concerns studies of environmental radiation, radiobiology, heavy particle ion therapy, diagnostic imaging, dose assessment and protection in medical radiation, brain function, systematic basic technology of nuclear sciences and international cooperation. Fact-finding studies are on the present situations of people exposed by nuclear experiment at Bikini Atoll in 1954 and of patients treated with thorotrast in past. Appendix cites the personnel name list, honorable events, cooperative studies, patent situation and others. (N.I.)

Estimating Return on Investment in Translational Research: Methods and Protocols

Science.gov (United States)

Trochim, William; Dilts, David M.; Kirk, Rosalind

2014-01-01

Assessing the value of clinical and translational research funding on accelerating the translation of scientific knowledge is a fundamental issue faced by the National Institutes of Health and its Clinical and Translational Awards (CTSA). To address this issue, the authors propose a model for measuring the return on investment (ROI) of one key CTSA program, the clinical research unit (CRU). By estimating the economic and social inputs and outputs of this program, this model produces multiple levels of ROI: investigator, program and institutional estimates. A methodology, or evaluation protocol, is proposed to assess the value of this CTSA function, with specific objectives, methods, descriptions of the data to be collected, and how data are to be filtered, analyzed, and evaluated. This paper provides an approach CTSAs could use to assess the economic and social returns on NIH and institutional investments in these critical activities. PMID:23925706

Estimating return on investment in translational research: methods and protocols.

Science.gov (United States)

Grazier, Kyle L; Trochim, William M; Dilts, David M; Kirk, Rosalind

2013-12-01

Assessing the value of clinical and translational research funding on accelerating the translation of scientific knowledge is a fundamental issue faced by the National Institutes of Health (NIH) and its Clinical and Translational Awards (CTSAs). To address this issue, the authors propose a model for measuring the return on investment (ROI) of one key CTSA program, the clinical research unit (CRU). By estimating the economic and social inputs and outputs of this program, this model produces multiple levels of ROI: investigator, program, and institutional estimates. A methodology, or evaluation protocol, is proposed to assess the value of this CTSA function, with specific objectives, methods, descriptions of the data to be collected, and how data are to be filtered, analyzed, and evaluated. This article provides an approach CTSAs could use to assess the economic and social returns on NIH and institutional investments in these critical activities.

Toward a Framework for Translational Research in School Psychology

Science.gov (United States)

Edwards, Oliver W.

2017-01-01

This article addresses a translational research framework for school psychology. Translational research uses outcomes of basic and applied science to enhance the overall well-being of persons. This transdisciplinary framework connects disciplines and uses their resources, capacities, systems, and procedures to advance prevention, intervention, and…

Pioneer Valley Life Sciences Institute Translational Biomedical Research

Energy Technology Data Exchange (ETDEWEB)

Schneider, Sallie; Shao, Rong; Schwartz, Lawrence; Jerry, D Joseph

2012-09-20

1. Analysis of angiogenic factors in breast cancer angiogenesis. Determine whether Acheron and YKL-40 were elevated in subsets of primary breast cancers and if they participated directly in determining the behavior of tumors. 2. Use of polymers for chemotherapeutic delivery to breast cancer tumors. The experiments were designed to define the utility of biocompatible polymers for addressing certain limitations and establish a flexible platform for delivery of diverse compound.

Section 7033 of the America COMPETES Act: Hispanic-Serving Institutions and Science, Technology, Engineering and Mathematics (STEM)

Science.gov (United States)

Gartrell, Sandra

2009-01-01

On March 1, 2009 from 2 pm to 5 pm at the Madison Hotel in Washington, DC, the National Science Foundation hosted a listening session, requesting input on Section 7033 of the America COMPETES (Creating Opportunities to Meaningfully Promote Excellence in Technology, Education, and Science) Act regarding Hispanic-serving institutions and science,…

Collective intelligence for translational medicine: Crowdsourcing insights and innovation from an interdisciplinary biomedical research community.

Science.gov (United States)

Budge, Eleanor Jane; Tsoti, Sandra Maria; Howgate, Daniel James; Sivakumar, Shivan; Jalali, Morteza

2015-01-01

Translational medicine bridges the gap between discoveries in biomedical science and their safe and effective clinical application. Despite the gross opportunity afforded by modern research for unparalleled advances in this field, the process of translation remains protracted. Efforts to expedite science translation have included the facilitation of interdisciplinary collaboration within both academic and clinical environments in order to generate integrated working platforms fuelling the sharing of knowledge, expertise, and tools to align biomedical research with clinical need. However, barriers to scientific translation remain, and further progress is urgently required. Collective intelligence and crowdsourcing applications offer the potential for global online networks, allowing connection and collaboration between a wide variety of fields. This would drive the alignment of biomedical science with biotechnology, clinical need, and patient experience, in order to deliver evidence-based innovation which can revolutionize medical care worldwide. Here we discuss the critical steps towards implementing collective intelligence in translational medicine using the experience of those in other fields of science and public health.

Member Perceptions of Informal Science Institution Graduate Certificate Program: Case Study of a Community of Practice

Science.gov (United States)

Ball, Lois A.

This research attempted to understand the experiences of a cohort of informal and formal science educators and informal science institution (ISI) community representatives during and after completion of a pilot graduate certificate program. Informal science educators (ISEs) find limited opportunities for professional development and support which influence their contributions to America's science literacy and school science education. This emergent design nested case study described how an innovative program provided professional development and enabled growth in participants' abilities to contribute to science literacy. Data were collected through interviews, participant observations, and class artifacts. The program by design and constituency was the overarching entity that accounted for members' experiences. Three principal aspects of the ISI certificate program and cohort which influenced perceptions and reported positive outcomes were (1) the cohort's composition and their collaborative activities which established a vigorous community of practice and fostered community building, mentoring, and networking, (2) long term program design and implementation which promoted experiential learning in a generative classroom, and (3) ability of some members who were able to be independent or autonomous learners to embrace science education reform strategies for greater self-efficacy and career advancement. This research extends the limited literature base for professional development of informal science educators and may benefit informal science institutions, informal and formal science educators, science education reform efforts, and public education and science-technology-society understanding. The study may raise awareness of the need to establish more professional development opportunities for ISEs and to fund professional development. Further, recognizing and appreciating informal science educators as a diverse committed community of professionals who positively

Translating public diplomacy and nation branding in Scandinavia

DEFF Research Database (Denmark)

Cassinger, Cecilia; Merkelsen, Henrik; Eksell, Jörgen

2016-01-01

Nation branding has been criticised for leading to the homogenisation and depoliticisation of national interest and identity. This study examines the politics of nation branding in relation to its configuration with public diplomacy and the institutional policy context in which they are embedded....... Informed by Scandinavian institutionalism and the analytical concept of translation, the study reveals that the way that nation branding relates to public diplomacy within an institutional context sets the frame for its politicisation. Translation enables the understanding of nation branding as a dynamic...... process of becoming that unfolds in relation to time and place. The research contributes to a more nuanced view on nation branding in presenting its toolbox practices as less determined by a corporate marketing logic. Despite the uniformity that allegedly characterises nation branding practices...

Synthetic Biology and the Translational Imperative.

Science.gov (United States)

Heidari Feidt, Raheleh; Ienca, Marcello; Elger, Bernice Simone; Folcher, Marc

2017-12-18

Advances at the interface between the biological sciences and engineering are giving rise to emerging research fields such as synthetic biology. Harnessing the potential of synthetic biology requires timely and adequate translation into clinical practice. However, the translational research enterprise is currently facing fundamental obstacles that slow down the transition of scientific discoveries from the laboratory to the patient bedside. These obstacles including scarce financial resources and deficiency of organizational and logistic settings are widely discussed as primary impediments to translational research. In addition, a number of socio-ethical considerations inherent in translational research need to be addressed. As the translational capacity of synthetic biology is tightly linked to its social acceptance and ethical approval, ethical limitations may-together with financial and organizational problems-be co-determinants of suboptimal translation. Therefore, an early assessment of such limitations will contribute to proactively favor successful translation and prevent the promising potential of synthetic biology from remaining under-expressed. Through the discussion of two case-specific inventions in synthetic biology and their associated ethical implications, we illustrate the socio-ethical challenges ahead in the process of implementing synthetic biology into clinical practice. Since reducing the translational lag is essential for delivering the benefits of basic biomedical research to society at large and promoting global health, we advocate a moral obligation to accelerating translational research: the "translational imperative."

New Developments At The Science Archives Of The NASA Exoplanet Science Institute

Science.gov (United States)

Berriman, G. Bruce

2018-06-01

The NASA Exoplanet Science Institute (NExScI) at Caltech/IPAC is the science center for NASA's Exoplanet Exploration Program and as such, NExScI operates three scientific archives: the NASA Exoplanet Archive (NEA) and Exoplanet Follow-up Observation Program Website (ExoFOP), and the Keck Observatory Archive (KOA).The NASA Exoplanet Archive supports research and mission planning by the exoplanet community by operating a service that provides confirmed and candidate planets, numerous project and contributed data sets and integrated analysis tools. The ExoFOP provides an environment for exoplanet observers to share and exchange data, observing notes, and information regarding the Kepler, K2, and TESS candidates. KOA serves all raw science and calibration observations acquired by all active and decommissioned instruments at the W. M. Keck Observatory, as well as reduced data sets contributed by Keck observers.In the coming years, the NExScI archives will support a series of major endeavours allowing flexible, interactive analysis of the data available at the archives. These endeavours exploit a common infrastructure based upon modern interfaces such as JuypterLab and Python. The first service will enable reduction and analysis of precision radial velocity data from the HIRES Keck instrument. The Exoplanet Archive is developing a JuypterLab environment based on the HIRES PRV interactive environment. Additionally, KOA is supporting an Observatory initiative to develop modern, Python based pipelines, and as part of this work, it has delivered a NIRSPEC reduction pipeline. The ensemble of pipelines will be accessible through the same environments.

78 FR 7794 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

Science.gov (United States)

2013-02-04

... Health Sciences Special Emphasis Panel, Sentinel Animal Study for Public Health. Date: February 27, 2013... from Environmental Exposures; 93.142, NIEHS Hazardous Waste Worker Health and Safety Training; 93.143...; 93.114, Applied Toxicological Research and Testing, National Institutes of Health, HHS) Dated...

Agricultural terminology in Russian language on the Institute of field and vegetable crops example

Directory of Open Access Journals (Sweden)

Savin Dragana

2014-01-01

Full Text Available Contemporary science demands that scientists are following domestic and foreign scientific and technical achievements through conference attendances and scientific and professional literature. Agricultural science is based on practical data, field experiments, but nevertheless it is essential to be up to date with the work of foreign researchers, scientific centers and institutions through their publications. The aim of this paper was to present a part of the agricultural lexicon (with the accent on the plant species names, as well as the general scientific and organizational terms with the equivalents in Russian - Serbian and Serbian - Russian, which is of the great importance in activities of Institute of Field and Vegetable Crops, presented through perennial practices of translation. Those terms are recognized as important and frequent, without wishing to go into professional divisions in agriculture as science. This paper is dedicated to the scientists who posses basic linguistic knowledge of Russian language and are starting to use Russian scientific and professional literature in agriculture, as well as students of Russian language for the purpose of establishing and widening linguistic fund.

Working with corpora in the translation classroom

Directory of Open Access Journals (Sweden)

Ralph Krüger

2012-10-01

Full Text Available This article sets out to illustrate possible applications of electronic corpora in the translation classroom. Starting with a survey of corpus use within corpus-based translation studies, the didactic value of corpora in the translation classroom and their epistemic value in translation teaching and practice will be elaborated. A typology of translation practice-oriented corpora will be presented, and the use of corpora in translation will be positioned within two general models of translation competence. Special consideration will then be given to the design and application of so-called Do-it-yourself (DIY corpora, which are compiled ad hoc with the aim of completing a specific translation task. In this context, possible sources for retrieving corpus texts will be presented and evaluated and it will be argued that, owing to time and availability constraints in real-life translation, the Internet should be used as a major source of corpus data. After a brief discussion of possible Internet research techniques for targeted and quality-focused corpus compilation, the possible use of the Internet itself as a macro-corpus will be elaborated. The article concludes with a brief presentation of corpus use in translation teaching in the MA in Specialised Translation Programme offered at Cologne University of Applied Sciences, Germany.

Science at Hampton Normal and Agricultural Institute, 1868-1893

Science.gov (United States)

Tucker, Linda Bart

Science had a variety of uses at Hampton Normal and Agricultural Institute, a private, missionary school supported by northern whites and Virginia's black land grant school from 1872 to 1920. Samuel Chapman Armstrong, principal for the first twenty-five years (1868-1893), advocated not classical but scientific studies, primarily as applied science to improve lives and "civilize" blacks and Indians. Agriculture and mechanics were practiced in Hampton's industries, where students worked their way through school. They were organized for production rather than instruction, though Armstrong claimed that labor had a moral value and that practical experience was valuable learning. In contrast to works by James D. Anderson and Donald Spivey, this study stresses the pragmatic, business purposes of Hampton's industries rather than any ideological agenda. Problems with providing specialized facilities, apparatus, and teachers made it difficult for Hampton to provide rigorous, graded science instruction. Students learned of practical applications of science in agricultural lectures and in such classes as physiology. However, the curriculum was designed for teacher training, using broad, elementary science for general knowledge, to train minds, and to make adult remedial language lessons more effective. Not surprisingly, very few graduates pursued careers which required more than general science studies. Besides the utilitarian and disciplinary purposes, Hampton used science to discourage superstitious ideas in religion. Armstrong also argued for racially distinctive education for blacks and Indians on the basis of scientific ideas about cultural evolution and inheritance of the experience of past generations. In practice, however, Hampton teachers adapted mainstream tools and methods of instruction. Not all teachers shared Armstrong's racial views, and several demonstrated concern for students, confidence in their ability, and professional interest in advancing them as

The Nuclear Security Science and Policy Institute at Texas A&M University

Directory of Open Access Journals (Sweden)

Claudio A. Gariazzo

2015-07-01

Full Text Available The Nuclear Security Science and Policy Institute (NSSPI is a multidisciplinary organization at Texas A&M University and was the first U.S. academic institution focused on technical graduate education, research, and service related to the safeguarding of nuclear materials and the reduction of nuclear threats. NSSPI employs science, engineering, and policy expertise to: (1 conduct research and development to help detect, prevent, and reverse nuclear and radiological proliferation and guard against nuclear terrorism; (2 educate the next generation of nuclear security and nuclear nonproliferation leaders; (3 analyze the interrelationships between policy and technology in the field of nuclear security; and (4 serve as a public resource for knowledge and skills to reduce nuclear threats. Since 2006, over 31 Doctoral and 73 Master degrees were awarded through NSSPI-sponsored research. Forty-one of those degrees are Master of Science in Nuclear Engineering with a specialization in Nuclear Nonproliferation and 16 were Doctorate of Philosophy degrees with a specific focus on nuclear nonproliferation. Over 200 students from both technical and policy backgrounds have taken classes provided by NSSPI at Texas A&M. The model for creating safeguards and security experts, which has in large part been replicated worldwide, was established at Texas A&M by NSSPI faculty and staff. In addition to conventional classroom lectures, NSSPI faculty have provided practical experiences; advised students on valuable research projects that have contributed substantially to the overall nuclear nonproliferation, safeguards and security arenas; and engaged several similar academic and research institutes around the world in activities and research for the benefit of Texas A&M students. NSSPI has had an enormous impact on the nuclear nonproliferation workforce (across the international community in the past 8 years, and this paper is an attempt to summarize the activities

Annual report of National Institute of Radiological Sciences, April 1988 - March 1989

International Nuclear Information System (INIS)

1989-07-01

The Annual Report of April 1988 - March 1989 provides the information on up-to-date research activities of the National Institute of Radiological Sciences (NIRS) in Japan. Researches undertaken in the NIRS aim at promoting medical application of radiation and at investigating health effects of radiation and radiation protection. The research scope is therefore widely ranging from physics to genetics and from environmental science to clinical medicine. In addition to basic researches carried out by 14 research divisions. This volume is divided into the following scientific categories for ease of reader's understanding: physics, chemistry, biochemistry and biophysics, cell biology, immunology and hematology, pathology and physiology, genetics, clinical research, and environmental science, covering a total of 84 titles. Activities of each research division and organization of the NIRS are given in appendix. (J.P.N.)

Computer Science Research Institute 2004 annual report of activities.

Energy Technology Data Exchange (ETDEWEB)

DeLap, Barbara J.; Womble, David Eugene; Ceballos, Deanna Rose

2006-03-01

This report summarizes the activities of the Computer Science Research Institute (CSRI) at Sandia National Laboratories during the period January 1, 2004 to December 31, 2004. During this period the CSRI hosted 166 visitors representing 81 universities, companies and laboratories. Of these 65 were summer students or faculty. The CSRI partially sponsored 2 workshops and also organized and was the primary host for 4 workshops. These 4 CSRI sponsored workshops had 140 participants--74 from universities, companies and laboratories, and 66 from Sandia. Finally, the CSRI sponsored 14 long-term collaborative research projects and 5 Sabbaticals.

Computer Science Research Institute 2003 annual report of activities.

Energy Technology Data Exchange (ETDEWEB)

DeLap, Barbara J.; Womble, David Eugene; Ceballos, Deanna Rose

2006-03-01

This report summarizes the activities of the Computer Science Research Institute (CSRI) at Sandia National Laboratories during the period January 1, 2003 to December 31, 2003. During this period the CSRI hosted 164 visitors representing 78 universities, companies and laboratories. Of these 78 were summer students or faculty members. The CSRI partially sponsored 5 workshops and also organized and was the primary host for 3 workshops. These 3 CSRI sponsored workshops had 178 participants--137 from universities, companies and laboratories, and 41 from Sandia. Finally, the CSRI sponsored 18 long-term collaborative research projects and 5 Sabbaticals.

Computer Science Research Institute 2005 annual report of activities.

Energy Technology Data Exchange (ETDEWEB)

Watts, Bernadette M.; Collis, Samuel Scott; Ceballos, Deanna Rose; Womble, David Eugene

2008-04-01

This report summarizes the activities of the Computer Science Research Institute (CSRI) at Sandia National Laboratories during the period January 1, 2005 to December 31, 2005. During this period, the CSRI hosted 182 visitors representing 83 universities, companies and laboratories. Of these, 60 were summer students or faculty. The CSRI partially sponsored 2 workshops and also organized and was the primary host for 3 workshops. These 3 CSRI sponsored workshops had 105 participants, 78 from universities, companies and laboratories, and 27 from Sandia. Finally, the CSRI sponsored 12 long-term collaborative research projects and 3 Sabbaticals.

What science for what kind of society? Reflecting the development of big science

CERN Multimedia

CERN. Geneva

2014-01-01

Lecture will be in English– Translation available in French Without any doubt, CERN can be described as being among the most ambitious scientific enterprises ever undertaken. For 60 years, the Member States have not only invested considerable financial means into this institution, but have also supported the creation of a highly visionary research programme. And this has led to a change in the way science is done, as captured by the idea of "big science". Yet this naturally also raises a number of quite fundamental questions: How did the meaning of "doing science" change? What justifies societal engagement with and support for such a cost-intensive long-term scientific undertaking? And finally, in what ways does (and did) this research enterprise contribute to the development of contemporary societies? By focusing on some key examples, the talk will thus explore how the ways of doing research and scientific and societal relations have undergone change over the ...

Translating Strategies of Boundary Spanners within an MNC

DEFF Research Database (Denmark)

Huerter O, Gabriela Gutierrez; Gold, Stefan; Moon, Jeremy

2016-01-01

Based on an embedded multiple case study of a UK-based MNC, informed by 27 semi-structured interviews and 20 follow-up interviews, this paper studies the translation of corporate social responsibility reporting (CSRR) within an MNC following its transfer from the HQ. Drawing from the Scandinavian...... institutionalism, with particular attention to Boxenbaum’s (2006b) three-dimensional framework of translation, the article conceptualises subsidiary translators as boundary spanners within the MNC and investigates the interplay of translators’ individual preferences, strategic framing and local grounding across...

Foreign Science and Engineering Presence in U.S. Institutions and the Labor Force

Science.gov (United States)

2008-07-23

United States, Washington, DC, May 2005, pp. 17-65. 8 Center for Immigration Studies, Davis, Donald R. and David E. Weinstein , United States Technological...Academy of Sciences, Wm. A. Wulf, President, National Academy of Engineering, and Harvey Fineberg, President, Institute of Medicine, December 13, 2002

Status of ion sources at National Institute of Radiological Sciences.

Science.gov (United States)

Kitagawa, A; Fujita, T; Goto, A; Hattori, T; Hamano, T; Hojo, S; Honma, T; Imaseki, H; Katagiri, K; Muramatsu, M; Sakamoto, Y; Sekiguchi, M; Suda, M; Sugiura, A; Suya, N

2012-02-01

The National Institute of Radiological Sciences (NIRS) maintains various ion accelerators in order to study the effects of radiation of the human body and medical uses of radiation. Two electrostatic tandem accelerators and three cyclotrons delivered by commercial companies have offered various life science tools; these include proton-induced x-ray emission analysis (PIXE), micro beam irradiation, neutron exposure, and radioisotope tracers and probes. A duoplasmatron, a multicusp ion source, a penning ion source (PIG), and an electron cyclotron resonance ion source (ECRIS) are in operation for these purposes. The Heavy-Ion Medical Accelerator in Chiba (HIMAC) is an accelerator complex for heavy-ion radiotherapy, fully developed by NIRS. HIMAC is utilized not only for daily treatment with the carbon beam but also for fundamental experiments. Several ECRISs and a PIG at HIMAC satisfy various research and clinical requirements.

Annual report of National Institute of Radiological Science in 1997

International Nuclear Information System (INIS)

1999-03-01

The research activities of National Institute of Radiological Science (NIRS) in 1997 are described, being divided into 14 categories: (1) heavy ion project research, (2) group research, (3) special research, (4) designated research, (5) ordinary research, (6) safety analysis research, (7) actual situation investigation, (8) accepted research, (9) general technology research for nuclear energy, (10) radioactivity investigation and research, (11) research for science and technology promotion, (12) international research cooperation, (13) safety evaluation for radioactive liquid waste reprocessing test, (14) human brain function research. The heavy ion project research is divided into 5 categories, further; (1) clinical research, (2) medical treatment research, (3) diagnosis research, (4) biological research, (5) physics and engineering research. A great number of research papers published are listed. Organization, personnel, budget and accounts of the NIRS are also mentioned in the report. (M. Suetake)

Developing Earth System Science Courses and Programs at Minority Serving Institutions

Science.gov (United States)

Johnson, D. R.; Jackson, C.; Ruzek, M.

2004-12-01

In the current NASA/USRA ESSE21 Program, emphasis is placed on the development of Earth System Science courses and degree offerings in Minority Serving Institutions (MSIs). Of the 18 colleges/universities being supported by NASA through USRA, 10 colleges/universities are MSIs. While there is recognition of the need for Earth system science courses, minors and degree programs by NASA and other agencies, within MSIs, a central challenge is how to provide a vision of the future opportunities in ESS and STEM disciplines that attracts and motivates students to these studies. Students need career guidance, role models and mentoring to encourage entry into STEM in general, and Earth system science in particular. Then there is the question of how to bring interested faculty together in institutions to form a critical mass that would forego the breadth and depth of disciplinary interests to undertake the development of multi/cross and interdisciplinary courses, minors and degree programs in ESS. Within the ESSE21 Diversity Working Group, the question has been raised as to how will MSIs ever be mainstream participants in ESS without teaching and engaging in research in remote sensing, modeling of the Earth's climate system and other like endeavors. Two other related questions raised within the Working Group are what are the long-term objectives of MSI adoption of ESS and what course corrections are needed to make ESS viable at MSIs. Within these considerations there are unresolved questions concerning the need and availability of resources from NASA, other agencies and local institutions. Apart from these larger considerations, efforts are underway within the ESSE21 Program that provide for sharing of resources among participants, organization of and access to materials that already exist, online resources, course outlines and successful listings for online resources by topics for particular courses and subject areas. The Lesson Learned Working Group, as well as the program

Sustaining the Clinical and Translational Research Workforce: Training and Empowering the Next Generation of Investigators.

Science.gov (United States)

Yin, Helen L; Gabrilove, Janice; Jackson, Rebecca; Sweeney, Carol; Fair, Alecia M; Toto, Robert

2015-07-01

There is mounting concern that clinician-scientists are a vanishing species and that the pipeline for clinical and translational research (CTR) investigators is in jeopardy. For the majority of current junior CTR investigators, the career path involves first obtaining a National Institutes of Health (NIH)-funded K-type career development award, particularly K08 and K23, and subsequently an NIH R01. This transition, popularly referred to as K2R, is a major hurdle with a low success rate and gaps in funding. In this Perspective, the authors identify factors that facilitate K2R transition and important aspects of increasing and sustaining the pipeline of CTR investigators. They also highlight significant differences in success rates of women and those underrepresented in biomedical research. Early career exposure to research methodology, protected time, multidisciplinary mentoring, and institutional "culture shift" are important for fostering and rewarding team science. Mentoring is the single most important contributor to K2R success, and emerging evidence suggests that formal mentor training and team mentoring are effective. Leadership training can empower junior investigators to thrive as independent CTR investigators. Future research should focus on delineating the difference between essential and supplemental factors to achieve this transition, and mentoring methods that foster success, including those that promote K2R transition of women and those underrepresented in biomedical research. The Clinical and Translational Science Awards National Consortium is well positioned to test existing models aimed at shortening the time frame, increasing the rate of K2R transition, and identifying strategies that improve success.

Community Advisory Boards Guiding Engaged Research Efforts within a Clinical Translational Sciences Award: Key Contextual Factors Explored.

Science.gov (United States)

Halladay, Jacqueline R; Donahue, Katrina E; Sleath, Betsy; Reuland, Dan; Black, Adina; Mitchell, C Madeline; Breland, Carol E; Coyne-Beasley, Tamera; Mottus, Kathleen; Watson, Sable Noelle; Lewis, Virginia; Wynn, Mysha; Corbie-Smith, Giselle

2017-01-01

Engaging stakeholders in research carries the promise of enhancing the research relevance, transparency, and speed of getting findings into practice. By describing the context and functional aspects of stakeholder groups, like those working as community advisory boards (CABs), others can learn from these experiences and operationalize their own CABs. Our objective is to describe our experiences with diverse CABs affiliated with our community engagement group within our institution's Clinical Translational Sciences Award (CTSA). We identify key contextual elements that are important to administering CABs. A group of investigators, staff, and community members engaged in a 6-month collaboration to describe their experiences of working with six research CABs. We identified the key contextual domains that illustrate how CABS are developed and sustained. Two lead authors, with experience with CABs and identifying contextual domains in other work, led a team of 13 through the process. Additionally, we devised a list of key tips to consider when devising CABs. The final domains include (1) aligned missions among stakeholders (2) resources/support, (3) defined operational processes/shared power, (4) well-described member roles, and (5) understanding and mitigating challenges. The tips are a set of actions that support the domains. Identifying key contextual domains was relatively easy, despite differences in the respective CAB's condition of focus, overall mission, or patient demographics represented. By contextualizing these five domains, other research and community partners can take an informed approach to move forward with CAB planning and engaged research.

Museum Institutions in Monuments - Positive and Negative Aspects of Adaptation: The New Amber Museum and Museum of Science in Gdansk, Poland

Science.gov (United States)

Piatkowska, Ksenia

2017-10-01

The issue of the creation and location of new museums is a current topic. The decision of where and how to create new museum facilities will impact successful function in the future. Museums are either located in newly designed buildings or in existing buildings. In general, existing buildings adapted for museum use are either formally under conservational protection or not. With regard to museum location in preserved monuments, the author notes that the true impact on authentic monumental building structure still needs intense research. The adaptation of the Great Mill and St. Catherine’s Church - two preserved medieval objects located in the historical city center of Gdansk - provide case studies to investigate positive and negative aspects. In both cases, the author carried out architectural projects for the functional purposes of museums: The New Amber Museum and Museum of Science. The author concludes that mutual benefits of adaptation result from: the financial means of the museum institution to invest long-term; the institutional respect of the museum towards heritage, which translates into respect for conservational protection; and the competitive advantage created by the monumental features of the building and the privileged location in a well-established, branded space. Negative aspects result from: space limitations of monuments that disable the museum from extending its exposition and thus prevent institutional development; the overly restrictive requirements of restoration that take priority over the museum mission; and the lack of technically functional space required for contemporary museum technologies, which forces unconventional engineering solutions that are more expensive than the location of the museum in a newly constructed building.

The Hermeneutical Approach in Translation Studies

Directory of Open Access Journals (Sweden)

Bernd Stefanink

2017-09-01

Full Text Available Our aim is to convince the reader of the validity of the hermeneutical approach in translation studies. In a first part, we will show that this validity is based on the fact that the hermeneutical approach integrates factors like subjectivity, intuition, corporeality and creativity in its theoretical reflection, being thus close to the reality of the translation process. In a second part, we will situate this approach in the context of the development of modern translation studies since the 1950s, and show that this development was characterized by a dominating tendency that led from an atomistic to a more and more holistic view of the translation unit, legitimating the holistic approach, which is fundamental in translational hermeneutics. Our third part relates the history of philosophical hermeneutics as the legitimate foundation of translational hermeneutics. In a fourth part, devoted to the “outcoming perspectives”, we will try to reinforce the legitimacy of the hermeneutical approach by showing how it is supported by recent results of research in cognitive science. In order to foster further research in translational hermeneutics we also offer a methodology based on hermeneutic principles to study the translation process. Finally, we give an example of legitimation of a creative problemsolving based on a hermeneutical approach of a translation problem which finds its validation in the results of cognitive research.

UCLA Translational Biomarker Development Program (UTBD)

Energy Technology Data Exchange (ETDEWEB)

Czernin, Johannes [Univ. of California, Los Angeles, CA (United States)

2014-09-01

The proposed UTBD program integrates the sciences of diagnostic nuclear medicine and (radio)chemistry with tumor biology and drug development. UTBD aims to translate new PET biomarkers for personalized medicine and to provide examples for the use of PET to determine pharmacokinetic (PK) and pharmacodynamic (PD) drug properties. The program builds on an existing partnership between the Ahmanson Translational Imaging Division (ATID) and the Crump Institute of Molecular Imaging (CIMI), the UCLA Department of Chemistry and the Division of Surgical Oncology. ATID provides the nuclear medicine training program, clinical and preclinical PET/CT scanners, biochemistry and biology labs for probe and drug development, radiochemistry labs, and two cyclotrons. CIMI provides DOE and NIH-funded training programs for radio-synthesis (START) and molecular imaging (SOMI). Other participating entities at UCLA are the Department of Chemistry and Biochemistry and the Division of Surgical Oncology. The first UTBD project focuses on deoxycytidine kinase, a rate-limiting enzyme in nucleotide metabolism, which is expressed in many cancers. Deoxycytidine kinase (dCK) positive tumors can be targeted uniquely by two distinct therapies: 1) nucleoside analog prodrugs such as gemcitabine (GEM) are activated by dCK to cytotoxic antimetabolites; 2) recently developed small molecule dCK inhibitors kill tumor cells by starving them of nucleotides required for DNA replication and repair. Since dCK-specific PET probes are now available, PET imaging of tumor dCK activity could improve the use of two different classes of drugs in a wide variety of cancers.

Journal of Mind and Medical Sciences: translational and integrative mission

Directory of Open Access Journals (Sweden)

David L. Rowland

2017-04-01

Full Text Available Initiated four years ago, Journal of Mind and Medical Sciences (J Mind Med Sci. established the mission to publish papers on mental and medical topics in distinct but closely interrelated domains. The editorial policy especially encourages interdisciplinary and integrative perspectives, being equally focused on basic research and clinical investigations and short reports. The journal adheres to the philosophy that high quality, original ideas and information should be readily accessible and freely shared within and amongst the scientific community. Accordingly, J Mind Med Sci. is an online, open access, non-for-profit journal which, because of individual/ private support, has levied no charges for submission, review, and publication of articles. All published articles may be freely downloaded and used by anyone from anywhere for scientific purposes. Journal of Mind and Medical Sciences is published by ValpoScholar/ Valparaiso University using the leading institutional repository platform of Digital Commons (powered by Bepress and under the local management of Jon Bull, Library Services, Valparaiso University, which combines submission management, editorial, and peer-review tools into a unique and flexible publishing software system. These editorial and publishing norms have facilitated the journal’s evolution, now indexed and abstracted in several international respected databases. Journal visibility is wide among international academic institutions and readers, as documented by the number of downloaded articles cited in respected journals, some indexed by Thomson Reuters and having high impact factors. In addition, published authors in J Mind Med Sci. periodically receive a statistical report about views / downloads of their articles. It is a pleasure and honor to thank all those who have thus far supported the journal activity (authors, reviewers, editorial board and assistance, publishing support, and to further invite and encourage

Socorro Students Translate NRAO Web Pages Into Spanish

Science.gov (United States)

2002-07-01

Six Socorro High School students are spending their summer working at the National Radio Astronomy Observatory (NRAO) on a unique project that gives them experience in language translation, World Wide Web design, and technical communication. Under the project, called "Un puente a los cielos," the students are translating many of NRAO's Web pages on astronomy into Spanish. "These students are using their bilingual skills to help us make basic information about astronomy and radio telescopes available to the Spanish-speaking community," said Kristy Dyer, who works at NRAO as a National Science Foundation postdoctoral fellow and who developed the project and obtained funding for it from the National Aeronautics and Space Administration. The students are: Daniel Acosta, 16; Rossellys Amarante, 15; Sandra Cano, 16; Joel Gonzalez, 16; Angelica Hernandez, 16; and Cecilia Lopez, 16. The translation project, a joint effort of NRAO and the NM Tech physics department, also includes Zammaya Moreno, a teacher from Ecuador, Robyn Harrison, NRAO's education officer, and NRAO computer specialist Allan Poindexter. The students are translating NRAO Web pages aimed at the general public. These pages cover the basics of radio astronomy and frequently-asked questions about NRAO and the scientific research done with NRAO's telescopes. "Writing about science for non-technical audiences has to be done carefully. Scientific concepts must be presented in terms that are understandable to non-scientists but also that remain scientifically accurate," Dyer said. "When translating this type of writing from one language to another, we need to preserve both the understandability and the accuracy," she added. For that reason, Dyer recruited 14 Spanish-speaking astronomers from Argentina, Mexico and the U.S. to help verify the scientific accuracy of the Spanish translations. The astronomers will review the translations. The project is giving the students a broad range of experience. "They are

Knowledge translation is the use of knowledge in health care decision making.

Science.gov (United States)

Straus, Sharon E; Tetroe, Jacqueline M; Graham, Ian D

2011-01-01

To provide an overview of the science and practice of knowledge translation. Narrative review outlining what knowledge translation is and a framework for its use. Knowledge translation is defined as the use of knowledge in practice and decision making by the public, patients, health care professionals, managers, and policy makers. Failures to use research evidence to inform decision making are apparent across all these key decision maker groups. There are several proposed theories and frameworks for achieving knowledge translation. A conceptual framework developed by Graham et al., termed the knowledge-to-action cycle, provides an approach that builds on the commonalities found in an assessment of planned action theories. Review of the evidence base for the science and practice of knowledge translation has identified several gaps including the need to develop valid strategies for assessing the determinants of knowledge use and for evaluating sustainability of knowledge translation interventions. Copyright © 2011 Elsevier Inc. All rights reserved.

Understanding bureaucracy in health science ethics: toward a better institutional review board.

Science.gov (United States)

Bozeman, Barry; Slade, Catherine; Hirsch, Paul

2009-09-01

Research involving human participants continues to grow dramatically, fueled by advances in medical technology, globalization of research, and financial and professional incentives. This creates increasing opportunities for ethical errors with devastating effects. The typical professional and policy response to calamities involving human participants in research is to layer on more ethical guidelines or strictures. We used a recent case-the Johns Hopkins University/Kennedy Kreiger Institute Lead Paint Study-to examine lessons learned since the Tuskegee Syphilis Study about the role of institutionalized science ethics in the protection of human participants in research. We address the role of the institutional review board as the focal point for policy attention.

TRANSLATING ECONOMICS TEXTBOOKS: A CASE STUDY OF EPISTEMICIDE

Directory of Open Access Journals (Sweden)

KARNEDI

2015-01-01

Full Text Available As part of discourse in the social sciences, economics textbooks written in English in which knowledge has been transferred to other languages through translation have brought a certain impact on both the target language and the target culture. In terms of ideology, this article argues about the hegemonic status of the dominant language or culture that creates socalled epistemicide or the erosion of knowledge, partly due to translation strategies adopted by the translator. Investigation is done using the corpusbased approach, theories of translation strategies and the comparative model. The study reveals that the translator in the macro-level text adopts the ideology of foreignising strategy rather than domesticating strategy when translating an economics textbook from English into Indonesian. This is supported by the use of the number of the source language-orientated translation techniques leading to two translation methods (i.e. literal translation and faithful translation adopted in the micro-level text. This research strongly supports another relevant study pertaining to the globalisation of knowledge through translation and also the translation theories of equivalence (i.e. overt and covert translation. The research findings also have some pedagogical implications on teaching English for Specific Purposes in higher education.

Research on Translation Strategy of English Subtitle Television Drama for College Students based on Cultural Differences

Directory of Open Access Journals (Sweden)

Zhou Gang

2016-01-01

Full Text Available Abstract. Translation strategy is closely-tied with the translation of ESTD (English Subtitle Television Drama. The research of translation strategy is to serve translations of ESTD in earlier days. The 21 S century is the information times. The development of science and technology is quick. Quantities of ESTD grow explosively. Translations of English Subtitle Television Dramas play a significant role in the progress of Chinese science and technology. Although the quality of traditional manual translations is very good, the speed of translation is too slow. Traditional manual translations can not meet the need of translations of ESTD day by day. It is a new topic to face the new stern challenge and follow the development's steps of the times for technical translators. The paper will discuss the transformation of translation idea, and suggest carrying on translation strategy, web page translation and software translation. Finally, the author states her views on the implementation of computer assistant translation, the managements of translation projects and information-shared platform.

Liaison activities with the Institute of Physical Chemistry, Russian Academy of Sciences: FY 1997

International Nuclear Information System (INIS)

Delegard, C.H.; Elovich, R.J.

1997-09-01

The Institute of Physical Chemistry of the Russian Academy of Sciences is conducting a program of fundamental and applied research into the chemistry of the actinides and technetium in alkaline media such as are present in the Hanford Site underground waste storage tanks. This work is being coordinated and the results disseminated through a technical liaison maintained at the Pacific Northwest National Laboratory. The technical liaison is performing laboratory studies on plutonium chemistry in alkaline media. The activities at the Institute of Physical Chemistry and through the liaison are pursued to improve understanding of the chemical behavior of key long-lived radioactive elements under current operating and proposed tank waste processing conditions. Both activities are supported by the Efficient Separations and Processing Crosscutting Program under the Office of Science and Technology of the U.S. Department of Energy

Annual report of National Institute of Radiological Sciences, 2005

International Nuclear Information System (INIS)

2006-10-01

Five years have passed since the National Institute of Radiological Sciences (NIRS) was reformed as an Independent Administrative Institution (IAI) in April 2001, and this fiscal year (2005-2006) is the last year in the first Mid-term Plan of NIRS. The main items of this report, being the same as the previous year's, are: the summary of NIRS activities; research and development including studies of important project, fundamental research, fundamental and frontier research, contract research and fact-finding; management; organization/budget/finance; and appendix. Important projects are radiological studies in advanced medicine, on sensitivity, of effects on human and of hazard. Fundamental research concerns studies of environmental radiation, radiobiology, heavy particle ion therapy, diagnostic imaging, dose assessment and protection in medical radiation, brain function, development of High-Coverage Expression Profiling (HiCEP) technique and new crossover studies. Fact-finding studies are on the present situations of people exposed by nuclear experiment at Bikini Atoll in 1954 and of patients treated with thorotrast in past. Appendix cites the personnel name list, honorable events, cooperative studies, patent situation and others. (J.P.N.)

Actor or arena: contrasting translations of a law on interorganizational integration.

Science.gov (United States)

Andersson, Johanna; Löfström, Mikael; Axelsson, Susanna Bihari; Axelsson, Runo

2012-01-01

A Swedish framework law has enabled integration between public agencies in vocational rehabilitation. With the support of this law, coordination associations can be formed to fund and organize joint activities. The purpose of this study is to describe and analyze how the law has been interpreted and translated into local coordination associations and how local institutional logics have developed to guide the organization of these associations. Data was collected through observations of meetings within two coordination associations and supplemented with documents. The material was analyzed by compilation and examination of data from field notes, whereupon the most important aspects were crystallized and framed with institutional organization theory. Two different translations of the law were seen in the associations studied: the association as an independent actor, and as an arena for its member organizations. Two subsequent institutional logics have developed, influencing decisions on autonomy, objectives and rationality for initiating and organizing in the two associations and their activities. The institutional logics are circular, further enhancing the different translations creating different forms of integration. Both forms of integration are legitimate, but the different translations have created integration with different degrees of autonomy in relation to the member organizations. Only a long-term analysis can show whether one form of integration is more functional than the other. This article is based on an extensive material providing insights into a form of interorganizational integration which has been scarcely researched. The findings show how different translations can influence the integration of welfare services.

Translational medicine and drug discovery

National Research Council Canada - National Science Library

Littman, Bruce H; Krishna, Rajesh

2011-01-01

..., and examples of their application to real-life drug discovery and development. The latest thinking is presented by researchers from many of the world's leading pharmaceutical companies, including Pfizer, Merck, Eli Lilly, Abbott, and Novartis, as well as from academic institutions and public- private partnerships that support translational research...

75 FR 38100 - National Institute of Environmental Health Sciences Superfund Hazardous Substance Research and...

Science.gov (United States)

2010-07-01

...- traditional communication methods to make the significance and applicability of SRP-funded research... and Social Sciences Research, and National Institute of Biomedical Imaging and Bioengineering. [cir... Superfund Hazardous Substance Research and Training Program Strategic Plan; Request for Comments ACTION...

Workshop on translating Science to Clinics and Market

OpenAIRE

Editor

2016-01-01

The workshop on translating technology is directed to senior industry leaders High tech entrepreneurs Scientists from academia and industry Clinical researchers and Venture capitalists. The event will cover various topics including startup success stories 19 inspiring showcases about advanced drug delivery systems.

Translating Scientific Conclusions about Risk for Public Audiences

Science.gov (United States)

Bowman, T. E.

2009-12-01

uncertainty. Scientific figures tend to either include too many different messages or over-generalize, and neither approach helps non-scientists identify useful metrics and apply them to decision-making. This session will briefly illustrate each of these problematic scientific conventions and present a more effective translation of key IPCC figures in a new graphic format that help non-scientists appreciate our situation and opportunities. This translation has received positive reviews from informal learning institutions and will be useful to the broader science communication community.

Annual report of the National Institute of Radiological Sciences

Science.gov (United States)

1992-01-01

The annual report for the activities of the National Institute of Radiological Sciences in Japan in the fiscal year 1990 is presented. The activities are divided into research, technical aids, training, medical services, management affairs at the Nakaminato Laboratory Branch Office, library or editing, international cooperation, and general affairs. Research activities are described under the following sections: (1) special researches covering biological risk evaluation in public exposure and exposure assessment in the environment and the public involved in food chain, medical use of accelerated heavy ions, and survey for the demonstration of dose-response relationships in low dose irradiation; (2) five assigned researches; (3) ordinary researches concerning physics, pharmacochemistry, biology, genetics, pathology and physiology, cell biology, internal exposure, environmental science, clinical research, clinical research for radiation injuries, medical use of heavy particles, environmental radiation ecology, and aquatic radiation ecology; (4) risk estimation of radiation; (5) survey for radiation response phenomena in fish and in immunity associated with low dose irradiation; (6) actual surveys for Bikini victims, population doses of medical and occupational exposure, and thorotrast exposure; (7) project research; (8) integrated atomic energy-based technological research; (9) radioactivity survey; (10) research supported by Science and Technology Agency aids; (11) International research cooperation; and (12) government-private joint cooperative study. Appendices include the personnel list and the bibliography of articles reported by the staff.

Institutional Infrastructure for Broader Impacts Engagement - Showcasing Effective Strategies and Approaches from a Large Research Institute

Science.gov (United States)

Gold, A. U.; Sullivan, S. B.; Smith, L. K.; Lynds, S. E.

2014-12-01

The need for robust scientific and especially climate literacy is increasing. Funding agencies mandate that scientists make their findings and data publically available. Ideally, this mandate is achieved by scientists and educators working together to translate research findings into common knowledge. The Cooperative Institute for Research in Environmental Sciences (CIRES) is the largest research institute at the University of Colorado and home institute to over 500 scientists. CIRES provides an effective organizational infrastructure to support its scientists in broadening their research impact. Education specialists provide the necessary experience, connections, logistical support, and evaluation expertise to develop and conduct impactful education and outreach efforts. Outreach efforts are tailored to the project needs and the scientists' interests. They span from deep engagement efforts with a high time commitment by the scientist thus a high dosage to short presentations by the scientists that reach many people without stimulating a deep engagement and have therefore a low dosage. We use three examples of current successful programs to showcase these different engagement levels and report on their impact: i) deep transformative and time-intensive engagement through a Research Experience for Community College students program, ii) direct engagement during a teacher professional development workshop centered around a newly developed curriculum bringing authentic climate data into secondary classrooms, iii) short-time engagement through a virtual panel discussion about the state of recent climate science topics, the recordings of which were repurposed in a Massive Open Online Course (MOOC). In this presentation, we discuss the challenges and opportunities of broader impacts work. We discuss successful strategies that we developed, stress the importance of robust impact evaluation, and summarize different avenues of funding outreach efforts.

Training trainers in health and human rights: implementing curriculum change in South African health sciences institutions.

Science.gov (United States)

Ewert, Elena G; Baldwin-Ragaven, Laurel; London, Leslie

2011-07-25

The complicity of the South African health sector in apartheid and the international relevance of human rights as a professional obligation prompted moves to include human rights competencies in the curricula of health professionals in South Africa. A Train-the-Trainers course in Health and Human Rights was established in 1998 to equip faculty members from health sciences institutions nationwide with the necessary skills, attitudes and knowledge to teach human rights to their students. This study followed up participants to determine the extent of curriculum implementation, support needed as well as barriers encountered in integrating human rights into health sciences teaching and learning. A survey including both quantitative and qualitative components was distributed in 2007 to past course participants from 1998-2006 via telephone, fax and electronic communication. Out of 162 past participants, 46 (28%) completed the survey, the majority of whom were still employed in academic settings (67%). Twenty-two respondents (48%) implemented a total of 33 formal human rights courses into the curricula at their institutions. Respondents were nine times more likely (relative risk 9.26; 95% CI 5.14-16.66) to implement human rights education after completing the training. Seventy-two extracurricular activities were offered by 21 respondents, many of whom had successfully implemented formal curricula. Enabling factors for implementation included: prior teaching experience in human rights, general institutional support and the presence of allies - most commonly coworkers as well as deans. Frequently cited barriers to implementation included: budget restrictions, time constraints and perceived apathy of colleagues or students. Overall, respondents noted personal enrichment and optimism in teaching human rights. This Train-the-Trainer course provides the historical context, educational tools, and collective motivation to incorporate human rights educational initiatives at health

Training Trainers in health and human rights: Implementing curriculum change in South African health sciences institutions

Directory of Open Access Journals (Sweden)

Baldwin-Ragaven Laurel

2011-07-01

Full Text Available Abstract Background The complicity of the South African health sector in apartheid and the international relevance of human rights as a professional obligation prompted moves to include human rights competencies in the curricula of health professionals in South Africa. A Train-the-Trainers course in Health and Human Rights was established in 1998 to equip faculty members from health sciences institutions nationwide with the necessary skills, attitudes and knowledge to teach human rights to their students. This study followed up participants to determine the extent of curriculum implementation, support needed as well as barriers encountered in integrating human rights into health sciences teaching and learning. Methods A survey including both quantitative and qualitative components was distributed in 2007 to past course participants from 1998-2006 via telephone, fax and electronic communication. Results Out of 162 past participants, 46 (28% completed the survey, the majority of whom were still employed in academic settings (67%. Twenty-two respondents (48% implemented a total of 33 formal human rights courses into the curricula at their institutions. Respondents were nine times more likely (relative risk 9.26; 95% CI 5.14-16.66 to implement human rights education after completing the training. Seventy-two extracurricular activities were offered by 21 respondents, many of whom had successfully implemented formal curricula. Enabling factors for implementation included: prior teaching experience in human rights, general institutional support and the presence of allies - most commonly coworkers as well as deans. Frequently cited barriers to implementation included: budget restrictions, time constraints and perceived apathy of colleagues or students. Overall, respondents noted personal enrichment and optimism in teaching human rights. Conclusion This Train-the-Trainer course provides the historical context, educational tools, and collective motivation

The innovation scorecard for continuous improvement applied to translational science.

Science.gov (United States)

Kotarba, Joseph A; Wooten, Kevin

2017-10-01

This paper reports on the baseline stage of a qualitative evaluation of the application of the Innovative Scorecard (ISC) to the Clinical and Translational Science Award (CTSA) at the University of Texas Medical Branch (UTMB) at Galveston. The ISC is adopted from the established Balanced Scorecard system for strategic planning and performance management. In formulating the evaluation, we focused on the organizational identity literature. The initial evaluation consisted of a series of semi-structured interviews with 22 participants of the ISC Boot Camp conducted in July 2015. The logic of grounded theory pointed to the clustering of perceptions of the ISC around respondents' occupational locations at UTMB. Administrators anticipate the expansion of planning activities to include a wider range of participants under the current CTSA award period (2015-2020) than under our first CTSA approval period (2009-2014). A common viewpoint among the senior scientists was that the scientific value of their work will continue to speak for itself without requiring the language of business. Junior scientists looked forward to the ISC's emphasis on increasingly horizontal leadership that will give them more access to and more control over their work and resources. Postdocs and senior staff welcomed increased involvement in the total research process at UTMB. The report concludes with strategies for future follow-up.

Post-doctoral research work developed at the National Institute for Fusion Science - Japan

International Nuclear Information System (INIS)

Ueda, M.

1992-05-01

This is a research report report on the work developed at the National Institute for Fusion Science - Japan, involving study of Beam Emission Spectroscopy. It describes the use of a fast neutral lithium beam (8 KeV) to measure the density profile in a Compact Helical Device. (A.C.A.S.)

Gender Equality in Public Higher Education Institutions of Ethiopia: The Case of Science, Technology, Engineering, and Mathematics

Science.gov (United States)

Egne, Robsan Margo

2014-01-01

Ensuring gender equality in higher education system is high on the agenda worldwide particularly in science disciplines. This study explores the problems and prospects of gender equality in public higher education institutions of Ethiopia, especially in science, technology, engineering, and mathematics. Descriptive survey and analytical research…

The chain reaction: a golden jubilee commemorative volume on research in basic sciences at DAE Institutions. V. 1

International Nuclear Information System (INIS)

2005-01-01

This book has been chosen to metaphorically reflect how research in basic sciences in various institutions of the Department of Atomic Energy (DAE) has evolved over the years, closely mimicking what goes on in a nuclear chain reactor. Since, for harnessing atomic energy for peaceful uses, nuclear physics and atomic physics are the two core activities, work was undertaken in these areas during initial days at the Tata Institute of Fundamental Research. These activities then promoted the growth of major programmes in a number of areas, such as, reactor physics, accelerator physics, condensed matter physics and materials science, theoretical physics and mathematical physics, astronomy and astrophysics, laser and plasma physics, radiation chemistry, photochemistry, chemical dynamics, nuclear chemistry, radiation biology and health sciences, molecular and cellular biology, structural biology and biophysics, agriculture and food sciences etc. In turn, all these programmes have been fostering the growth in several other domains of science, engineering and technology

Evidence-Based Scholarly Communication: Information Professionals Unlocking Translational Research

Directory of Open Access Journals (Sweden)

Philip J. Kroth

2010-12-01

Full Text Available The Evidence-Based Scholarly Communication Conference (EBSCC was held March 11-12, 2010 in Albuquerque, NM. The conference addressed the perceived gap in knowledge and training for scholarly communication principles in the National Institutes of Health (NIH Clinical and Translational Science Award (CTSA Program. The EBSCC brought together librarians and information specialists to share evidence based strategies for developing effective local scholarly communication support and training and, it is hoped, to form new coalitions to address this topic at the local and national levels. This brief communication summarizes the need for theconference, highlights the general sessions in order of presentation, and introduces the EBSCC research papers appearing in this issue of Evidence Based Library and Information Practice (EBLIP. It also includes a description of a unique peer-review process methodology pioneered at EBSCC.

Biomedical optics centers: forty years of multidisciplinary clinical translation for improving human health

Science.gov (United States)

Tromberg, Bruce J.; Anderson, R. Rox; Birngruber, Reginald; Brinkmann, Ralf; Berns, Michael W.; Parrish, John A.; Apiou-Sbirlea, Gabriela

2016-12-01

Despite widespread government and public interest, there are significant barriers to translating basic science discoveries into clinical practice. Biophotonics and biomedical optics technologies can be used to overcome many of these hurdles, due, in part, to offering new portable, bedside, and accessible devices. The current JBO special issue highlights promising activities and examples of translational biophotonics from leading laboratories around the world. We identify common essential features of successful clinical translation by examining the origins and activities of three major international academic affiliated centers with beginnings traceable to the mid-late 1970s: The Wellman Center for Photomedicine (Mass General Hospital, USA), the Beckman Laser Institute and Medical Clinic (University of California, Irvine, USA), and the Medical Laser Center Lübeck at the University of Lübeck, Germany. Major factors driving the success of these programs include visionary founders and leadership, multidisciplinary research and training activities in light-based therapies and diagnostics, diverse funding portfolios, and a thriving entrepreneurial culture that tolerates risk. We provide a brief review of how these three programs emerged and highlight critical phases and lessons learned. Based on these observations, we identify pathways for encouraging the growth and formation of similar programs in order to more rapidly and effectively expand the impact of biophotonics and biomedical optics on human health.

Annual report of National Institute of Radiological Science, April 1996 - March 1997

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-03-01

This report presents a brief summary of the research activities and the achievements in the Institute for the fiscal year of 1996. The clinical trial of cancer therapy using heavy ion beams have been progressed with promising results. Various kinds of basic studies using the heavy ion beams have been performed in an open use system and remarkable outcomes have been derived from many collaborative researchers. The reported topics extended over several categories including physics, chemistry, biology, medicine, radiopharmacy and environmental science. As another important role of the Institute, training of personnels who are being engaged in and willing to come into the radiation-related fields such as radiation protection, nursing, emergency measures, biomedicine, etc. was carried out. This report presents a total of 91 abstracts of researches made in the institute and the list of publications in the fiscal year of 1996. (M.N.)

The Impact of Machine Translation and Computer-aided Translation on Translators

Science.gov (United States)

Peng, Hao

2018-03-01

Under the context of globalization, communications between countries and cultures are becoming increasingly frequent, which make it imperative to use some techniques to help translate. This paper is to explore the influence of computer-aided translation on translators, which is derived from the field of the computer-aided translation (CAT) and machine translation (MT). Followed by an introduction to the development of machine and computer-aided translation, it then depicts the technologies practicable to translators, which are trying to analyze the demand of designing the computer-aided translation so far in translation practice, and optimize the designation of computer-aided translation techniques, and analyze its operability in translation. The findings underline the advantages and disadvantages of MT and CAT tools, and the serviceability and future development of MT and CAT technologies. Finally, this thesis probes into the impact of these new technologies on translators in hope that more translators and translation researchers can learn to use such tools to improve their productivity.

Overview of graduate training program of John Adams Institute for Accelerator Science

Science.gov (United States)

Seryi, Andrei

The John Adams Institute for Accelerator Science is a center of excellence in the UK for advanced and novel accelerator technology, providing expertise, research, development and training in accelerator techniques, and promoting advanced accelerator applications in science and society. We work in JAI on design of novel light sources upgrades of 3-rd generation and novel FELs, on plasma acceleration and its application to industrial and medical fields, on novel energy recovery compact linacs and advanced beam diagnostics, and many other projects. The JAI is based on three universities - University of Oxford, Imperial College London and Royal Holloway University of London. Every year 6 to 10 accelerators science experts, trained via research on cutting edge projects, defend their PhD thesis in JAI partner universities. In this presentation we will overview the research and in particular the highly successful graduate training program in JAI.

A Graduate Professional Program in Translation.

Science.gov (United States)

Waldinger, Renee

1987-01-01

The City University of New York Graduate School's professional program in translation combines high-level, specialized language learning in French, German, and Spanish with related graduate work in such disciplines as international affairs, finance, banking, jurisprudence, literature, and computer science. (CB)

Implementing 'translational' biomedical research: convergence and divergence among clinical and basic scientists.

Science.gov (United States)

Morgan, Myfanwy; Barry, Christine A; Donovan, Jenny L; Sandall, Jane; Wolfe, Charles D A; Boaz, Annette

2011-10-01

Universities are increasingly regarded as key actors in the new 'knowledge economy', with requirements to produce market-oriented knowledge and engage in commercialization. This is of particular significance in the biomedical field, reflecting the perceived gap between success in terms of scientific discoveries and its transformation into products. The dominant discourse attributes this situation to 'blocks' in the translational pathway from 'bench to bedside', leading to policies to 'reengineer' the research enterprise. This study examines a pilot initiative established by the UK's Medical Research Council (MRC). This involved employing a change agent (Research Translator) supported by a small amount of translational funding to promote the culture and practice of translational research at a university/hospital site in England. An ethnographically informed case study involving semi-structured and open exploratory interviews, observation and document review, was conducted in 2008. Analysis and interpretation were informed by Bourdieu's logic of practice applied to science. The requirements of translational research promoted by the Research Translator and its sources of capital (authority, prestige etc) were largely congruent with the 'field' of clinical science. In contrast, translational research diverged from perceptions of 'legitimate' science and requirements for capital accumulation held by the majority of basic scientists who often described this research as 'high risk' and were resistant to the Research Translator's advice. However some differences in motivations and practices were identified within groups of scientists associated with career stage, work environment and specialty. We argue that there are convergent and divergent forces that influence scientists' readiness to adopt a market-oriented translational research model and in turn facilitate or constrain the effectiveness of a knowledge broker. We also identify ways in which current structures and

UCSD's Institute of Engineering in Medicine: fostering collaboration through research and education.

Science.gov (United States)

Chien, Shu

2012-07-01

The University of California, San Diego (UCSD) was established in 1961 as a new research university that emphasizes innovation, excellence, and interdisciplinary research and education. It has a School of Medicine (SOM) and the Jacobs School of Engineering (JSOE) in close proximity, and both schools have national rankings among the top 15. In 1991, with the support of the Whitaker Foundation, the Whitaker Institute of Biomedical Engineering was formed to foster collaborations in research and education. In 2008, the university extended the collaboration further by establishing the Institute of Engineering in Medicine (IEM), with the mission of accelerating the discoveries of novel science and technology to enhance health care through teamwork between engineering and medicine, and facilitating the translation of innovative technologies for delivery to the public through clinical application and commercialization.

Binary translation using peephole translation rules

Science.gov (United States)

Bansal, Sorav; Aiken, Alex

2010-05-04

An efficient binary translator uses peephole translation rules to directly translate executable code from one instruction set to another. In a preferred embodiment, the translation rules are generated using superoptimization techniques that enable the translator to automatically learn translation rules for translating code from the source to target instruction set architecture.

Linguistic Levels of Translation: A Generic Exploration of Translation Difficulties in Literary Textual Corpus

Directory of Open Access Journals (Sweden)

Magda Madkour

2016-11-01

Social Sciences (SPSS, and qualitative data depended on the software NVivo. The results of data analysis indicated a correlation between using cognitive teaching methodology and students’ performance in literary translation. The themes that emerged from the qualitative analysis referred to topics related to causes of  translation problems, including lack of experience in the field of literary translation; weakness in literary translation skills; and challenges in interpreting literary devices and eloquence. Data analysis revealed that these problems were due to using traditional teaching methods that were based on giving lectures and direct instructions, and rote learning. The emergent themes concerning ways of resolving these problems include the importance of employing cognitive methods to stimulate students’ creative abilities, and motivate them to improve their analytical and critical thinking.  The discussions, presented in the literature review of the present study, focus on five issues: the linguistics levels of literary translation; the characteristics of literary texts; the problems of translating literary texts; the main principles of the cognitive method which makes it appropriate for teaching literary translation; and the relationship between literary translation theories, cognition, and creativity. The research recommendations highlight the importance of bridging the gap between translation theory and practice to provide strategies for solving the problems of translating literary texts. The recommendations also include the procedures for integrating Newmark’s translation theory into cognitive taxonomies to enhance students’ knowledge, and help them acquire refined skills for translating literary texts efficiently.

Machine Translation - A Gentle Introduction

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 3; Issue 7. Machine Translation - A Gentle Introduction. Durgesh D Rao. General Article Volume 3 Issue 7 July 1998 pp 61-70. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/003/07/0061-0070 ...

Translating The Infinities by John Banville

OpenAIRE

Irene Abigail Piccinini

2015-01-01

Abstract - John Banville’s talent as a prose stylist is widely recognized. The polished elegance of his phrases constitutes a continuing and fascinating challenge for his translator, due to the intricacies of the source text, its manifold registers and lexical choices. In his novel The Infinities, in Italian Teoria degli Infiniti, John Banville takes cue from Kleist’s Amphytrion to devise a novel where classicality interweaves with science and science fiction through the invention of a world ...

Critical appraisal of the suitability of translational research models for performance assessment of cancer institutions

NARCIS (Netherlands)

Rajan, A.; Sullivan, R.; Bakker, S.; van Harten, Willem H.

2012-01-01

Background. Translational research is a complex cumulative process that takes time. However, the operating environment for cancer centers engaged in translational research is now financially insecure. Centers are challenged to improve results and reduce time from discovery to practice innovations.

Chinese literary works translated into Baba Malay: a bibliographical study

OpenAIRE

Yoong, S. K.; Zainab, A.N.

2002-01-01

Analyses 68 unique titles of Baba translated works published between 1889 and 1950. The titles are held in the libraries of the University of Malaya (UM), Science University Malaysia (USM), National University of Malaysia (UKM), the Dewan Bahasa dan Pustaka (DBP), National University of Singapore (NUS), National Library of Singapore (NLS) and the British Library (BL). The results reveal three periods of active publication of Baba translated works. A total of 18 works were translated before Wo...

Evaluation of the SYSTRAN Automatic Translation System. Report No. 5.

Science.gov (United States)

Chaumier, Jacques; And Others

The Commission of the European Communities has acquired an automatic translation system (SYSTRAN), which has been put into operation on an experimental basis. The system covers translation of English into French and comprises a dictionary for food science and technology containing 25,000 words or inflections and 4,500 expressions. This report…

Annual report: AEC Institute for Life Sciences, 1986

International Nuclear Information System (INIS)

1987-08-01

The AEC-Institute for life sciences research programme can be divided into four divisions: experimental nuclear medicine, radiobiology, radiopharmacy and hormone receptor studies. The experimental nuclear medicine division investigates and undertakes new developments in nuclear diagnostics with a view to clinical application, especially developments in dataprocessing techniques and radiopharmaceuticals. Physiological, biochemical and pharmacological problems are also investigated by using tracers and nuclear diagnostic techniques. The radiobiology division is concerned with the development of biochemical techniques for determining radiosensitivity amongst radiation workers as well as clinical-biochemical, diagnostic procedures for identifying exposure to ionizing types of radiation (X- or gamma radiation). The hormone receptor division is concerned with the study of the role of steroid hormone receptors, steroids and carcinogenes in the etiology of breast cancer. Research projects as well as completed and ongoing research are listed in this report

[Activities of Research Institute for Advanced Computer Science

Science.gov (United States)

Gross, Anthony R. (Technical Monitor); Leiner, Barry M.

2001-01-01

The Research Institute for Advanced Computer Science (RIACS) carries out basic research and technology development in computer science, in support of the National Aeronautics and Space Administrations missions. RIACS is located at the NASA Ames Research Center, Moffett Field, California. RIACS research focuses on the three cornerstones of IT research necessary to meet the future challenges of NASA missions: 1. Automated Reasoning for Autonomous Systems Techniques are being developed enabling spacecraft that will be self-guiding and self-correcting to the extent that they will require little or no human intervention. Such craft will be equipped to independently solve problems as they arise, and fulfill their missions with minimum direction from Earth. 2. Human-Centered Computing Many NASA missions require synergy between humans and computers, with sophisticated computational aids amplifying human cognitive and perceptual abilities. 3. High Performance Computing and Networking Advances in the performance of computing and networking continue to have major impact on a variety of NASA endeavors, ranging from modeling and simulation to analysis of large scientific datasets to collaborative engineering, planning and execution. In addition, RIACS collaborates with NASA scientists to apply IT research to a variety of NASA application domains. RIACS also engages in other activities, such as workshops, seminars, visiting scientist programs and student summer programs, designed to encourage and facilitate collaboration between the university and NASA IT research communities.

MD-CTS: An integrated terminology reference of clinical and translational medicine

Directory of Open Access Journals (Sweden)

Will Ray

2016-01-01

Full Text Available New vocabularies are rapidly evolving in the literature relative to the practice of clinical medicine and translational research. To provide integrated access to new terms, we developed a mobile and desktop online reference—Marshfield Dictionary of Clinical and Translational Science (MD-CTS. It is the first public resource that comprehensively integrates Wiktionary (word definition, BioPortal (ontology, Wiki (image reference, and Medline abstract (word usage information. MD-CTS is accessible at http://spellchecker.mfldclin.edu/. The website provides a broadened capacity for the wider clinical and translational science community to keep pace with newly emerging scientific vocabulary. An initial evaluation using 63 randomly selected biomedical words suggests that online references generally provided better coverage (73%-95% than paper-based dictionaries (57–71%.

Institutional repository in communication: the REPOSCOM project implemented in the digital libraries federation of communication science

Directory of Open Access Journals (Sweden)

Sueli Mara Soares Pinto Ferreira

2007-01-01

Full Text Available Considering the conceptualization, characterization and context of the institutional repositories (IR this paper discuss the procedures, policies and strategies delineated to the implementation of IR in a research environment. The object of discussion is the project called Reposcom - Institutional Repository of Intercom (Brazilian Society of Interdisciplinary Studies of Communication – which is part of a broader project managed by the Portcom – Information Network in Communication Sciences of Countries of Portuguese Language – and called Digital Libraries Federation in the Communication Sciences. Aiming to share the knowledge and experience acquired with the implementation of the Reposcom, this paper describes its work activities, the decisions made, the customization of the software DSpace (the technological solution and the initial results achieved with the project.

Institutional capacity for health systems research in East and Central African schools of public health: knowledge translation and effective communication.

Science.gov (United States)

Ayah, Richard; Jessani, Nasreen; Mafuta, Eric M

2014-06-02

Local health systems research (HSR) provides policymakers and practitioners with contextual, evidence-based solutions to health problems. However, producers and users of HSR rarely understand the complexities of the context within which each operates, leading to the "know-do" gap. Universities are well placed to conduct knowledge translation (KT) integrating research production with uptake. The HEALTH Alliance Africa Hub, a consortium of seven schools of public health (SPHs) in East and Central Africa, was formed to build capacity in HSR. This paper presents information on the capacity of the various SPHs to conduct KT activities. In 2011, each member of the Africa Hub undertook an institutional HSR capacity assessment using a context-adapted and modified self-assessment tool. KT capacity was measured by several indicators including the presence of a KT strategy, an organizational structure to support KT activities, KT skills, and institutional links with stakeholders and media. Respondents rated their opinions on the various indicators using a 5-point Likert scale. Averages across all respondents for each school were calculated. Thereafter, each school held a results validation workshop. A total of 123 respondents from all seven SPHs participated. Only one school had a clear KT strategy; more commonly, research was disseminated at scientific conferences and workshops. While most respondents perceived their SPH as having strong institutional ties with organizations interested in HSR as well as strong institutional leadership, the organizational structures required to support KT activities were absent. Furthermore, individual researchers indicated that they had little time or skills to conduct KT. Additionally, institutional and individual links with policymakers and media were reported as weak. Few SPHs in Africa have a clear KT strategy. Strengthening the weak KT capacity of the SPHs requires working with institutional leadership to develop KT strategies designed

Ames Life Science Data Archive: Translational Rodent Research at Ames

Science.gov (United States)

Wood, Alan E.; French, Alison J.; Ngaotheppitak, Ratana; Leung, Dorothy M.; Vargas, Roxana S.; Maese, Chris; Stewart, Helen

2014-01-01

The Life Science Data Archive (LSDA) office at Ames is responsible for collecting, curating, distributing and maintaining information pertaining to animal and plant experiments conducted in low earth orbit aboard various space vehicles from 1965 to present. The LSDA will soon be archiving data and tissues samples collected on the next generation of commercial vehicles; e.g., SpaceX & Cygnus Commercial Cargo Craft. To date over 375 rodent flight experiments with translational application have been archived by the Ames LSDA office. This knowledge base of fundamental research can be used to understand mechanisms that affect higher organisms in microgravity and help define additional research whose results could lead the way to closing gaps identified by the Human Research Program (HRP). This poster will highlight Ames contribution to the existing knowledge base and how the LSDA can be a resource to help answer the questions surrounding human health in long duration space exploration. In addition, it will illustrate how this body of knowledge was utilized to further our understanding of how space flight affects the human system and the ability to develop countermeasures that negate the deleterious effects of space flight. The Ames Life Sciences Data Archive (ALSDA) includes current descriptions of over 700 experiments conducted aboard the Shuttle, International Space Station (ISS), NASA/MIR, Bion/Cosmos, Gemini, Biosatellites, Apollo, Skylab, Russian Foton, and ground bed rest studies. Research areas cover Behavior and Performance, Bone and Calcium Physiology, Cardiovascular Physiology, Cell and Molecular Biology, Chronobiology, Developmental Biology, Endocrinology, Environmental Monitoring, Gastrointestinal Physiology, Hematology, Immunology, Life Support System, Metabolism and Nutrition, Microbiology, Muscle Physiology, Neurophysiology, Pharmacology, Plant Biology, Pulmonary Physiology, Radiation Biology, Renal, Fluid and Electrolyte Physiology, and Toxicology. These

English translations of German standards. Catalogue 1988. 24. ed.

International Nuclear Information System (INIS)

1988-01-01

The catalogue contains a list of all currently available English translations of DIN standards, and of English translations of DIN handbooks, a numerical index, an alphabetical index, and an index of DIN EN, DIN IEC, DIN ISO standards, LN and VG standards. Some useful information on standards work in Germany and on the activities of DIN Deutsches Institut fuer Normung e.V. is given. (orig./HP)

Summary of researches being performed in the Institute of Mathematics and Computer Science on computer science and information technologies

Directory of Open Access Journals (Sweden)

Artiom Alhazov

2008-07-01

Full Text Available Evolution of the informatization notion (which assumes automation of majority of human activities applying computers, computer networks, information technologies towards the notion of {\\it Global Information Society} (GIS challenges the determination of new paradigms of society: automation and intellectualization of production, new level of education and teaching, formation of new styles of work, active participation in decision making, etc. To assure transition to GIS for any society, including that from Republic of Moldova, requires both special training and broad application of progressive technologies and information systems. Methodological aspects concerning impact of GIS creation over the citizen, economic unit, national economy in the aggregate demands a profound study. Without systematic approach to these aspects the GIS creation would have confront great difficulties. Collective of researchers from the Institute of Mathematics and Computer Science (IMCS of Academy of Sciences of Moldova, which work in the field of computer science, constitutes the center of advanced researches and activates in those directions of researches of computer science which facilitate technologies and applications without of which the development of GIS cannot be assured.

Application of LSP texts in translator training

Directory of Open Access Journals (Sweden)

Larisa Ilynska

2017-06-01

Full Text Available The paper presents discussion of the results of extensive empirical research into efficient methods of educating and training translators of LSP (language for special purposes texts. The methodology is based on using popular LSP texts in the respective fields as one of the main media for translator training. The aim of the paper is to investigate the efficiency of this methodology in developing thematic, linguistic and cultural competences of the students, following Bloom’s revised taxonomy and European Master in Translation Network (EMT translator training competences. The methodology has been tested on the students of a professional Master study programme called Technical Translation implemented by the Institute of Applied Linguistics, Riga Technical University, Latvia. The group of students included representatives of different nationalities, translating from English into Latvian, Russian and French. Analysis of popular LSP texts provides an opportunity to structure student background knowledge and expand it to account for linguistic innovation. Application of popular LSP texts instead of purely technical or scientific texts characterised by neutral style and rigid genre conventions provides an opportunity for student translators to develop advanced text processing and decoding skills, to develop awareness of expressive resources of the source and target languages and to develop understanding of socio-pragmatic language use.

75 FR 36111 - Notice of Inventory Completion: Cranbrook Institute of Science, Bloomfield Hills, MI

Science.gov (United States)

2010-06-24

... the Little Traverse Bay Bands of Odawa Indians, Michigan, on behalf of the Michigan Anishnaabek..., Oakland County Medical Examiner (CIS reference 9738 and 9739). No known individuals were identified. No... to the Cranbrook Institute of Science by the Little Traverse Bay Bands of the Odawa Indians on behalf...

Machine Translation and Other Translation Technologies.

Science.gov (United States)

Melby, Alan

1996-01-01

Examines the application of linguistic theory to machine translation and translator tools, discusses the use of machine translation and translator tools in the real world of translation, and addresses the impact of translation technology on conceptions of language and other issues. Findings indicate that the human mind is flexible and linguistic…

Research in progress and other activities of the Institute for Computer Applications in Science and Engineering

Science.gov (United States)

1993-01-01

This report summarizes research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics and computer science during the period April 1, 1993 through September 30, 1993. The major categories of the current ICASE research program are: (1) applied and numerical mathematics, including numerical analysis and algorithm development; (2) theoretical and computational research in fluid mechanics in selected areas of interest to LaRC, including acoustic and combustion; (3) experimental research in transition and turbulence and aerodynamics involving LaRC facilities and scientists; and (4) computer science.

American Institute of Biological Sciences

Science.gov (United States)

... Staff Issues AIBS Position Statements Funding for the Biological Sciences Supporting Scientific Collections Advocating for Research Policy ... Public Policy Leadership Award Graduate students in the biological sciences who have demonstrated initiative and leadership in ...