Chemometrics-based process analytical technology (PAT) tools: applications and adaptation in pharmaceutical and biopharmaceutical industries.

Science.gov (United States)

Challa, Shruthi; Potumarthi, Ravichandra

2013-01-01

Process analytical technology (PAT) is used to monitor and control critical process parameters in raw materials and in-process products to maintain the critical quality attributes and build quality into the product. Process analytical technology can be successfully implemented in pharmaceutical and biopharmaceutical industries not only to impart quality into the products but also to prevent out-of-specifications and improve the productivity. PAT implementation eliminates the drawbacks of traditional methods which involves excessive sampling and facilitates rapid testing through direct sampling without any destruction of sample. However, to successfully adapt PAT tools into pharmaceutical and biopharmaceutical environment, thorough understanding of the process is needed along with mathematical and statistical tools to analyze large multidimensional spectral data generated by PAT tools. Chemometrics is a chemical discipline which incorporates both statistical and mathematical methods to obtain and analyze relevant information from PAT spectral tools. Applications of commonly used PAT tools in combination with appropriate chemometric method along with their advantages and working principle are discussed. Finally, systematic application of PAT tools in biopharmaceutical environment to control critical process parameters for achieving product quality is diagrammatically represented.

Process analytical technology (PAT) tools for the cultivation step in biopharmaceutical production

NARCIS (Netherlands)

Streefland, M.; Martens, D.E.; Beuvery, E.C.; Wijffels, R.H.

2013-01-01

The process analytical technology (PAT) initiative is now 10 years old. This has resulted in the development of many tools and software packages dedicated to PAT application on pharmaceutical processes. However, most applications are restricted to small molecule drugs, mainly for the relatively

PAT-1 safety analysis report addendum.

Energy Technology Data Exchange (ETDEWEB)

Weiner, Ruth F.; Schmale, David T.; Kalan, Robert J.; Akin, Lili A.; Miller, David Russell; Knorovsky, Gerald Albert; Yoshimura, Richard Hiroyuki; Lopez, Carlos; Harding, David Cameron; Jones, Perry L.; Morrow, Charles W.

2010-09-01

The Plutonium Air Transportable Package, Model PAT-1, is certified under Title 10, Code of Federal Regulations Part 71 by the U.S. Nuclear Regulatory Commission (NRC) per Certificate of Compliance (CoC) USA/0361B(U)F-96 (currently Revision 9). The purpose of this SAR Addendum is to incorporate plutonium (Pu) metal as a new payload for the PAT-1 package. The Pu metal is packed in an inner container (designated the T-Ampoule) that replaces the PC-1 inner container. The documentation and results from analysis contained in this addendum demonstrate that the replacement of the PC-1 and associated packaging material with the T-Ampoule and associated packaging with the addition of the plutonium metal content are not significant with respect to the design, operating characteristics, or safe performance of the containment system and prevention of criticality when the package is subjected to the tests specified in 10 CFR 71.71, 71.73 and 71.74.

Spatial variation of transit service quality preferences in Dar-es-Salaam

NARCIS (Netherlands)

Nkurunziza, A.; Zuidgeest, M.H.P.; Brussel, M.J.G.; van den Bosch, F.H.M.; van den Bosch, Frans

2012-01-01

Commuter preferences for transit service quality are of great importance to transit service providers and regulatory agencies. The point of view of potential passengers is fundamental for evaluating transit service quality as they are envisaged to be the real consumers of the planned services and

iPat: intelligent prediction and association tool for genomic research.

Science.gov (United States)

Chen, Chunpeng James; Zhang, Zhiwu

2018-06-01

The ultimate goal of genomic research is to effectively predict phenotypes from genotypes so that medical management can improve human health and molecular breeding can increase agricultural production. Genomic prediction or selection (GS) plays a complementary role to genome-wide association studies (GWAS), which is the primary method to identify genes underlying phenotypes. Unfortunately, most computing tools cannot perform data analyses for both GWAS and GS. Furthermore, the majority of these tools are executed through a command-line interface (CLI), which requires programming skills. Non-programmers struggle to use them efficiently because of the steep learning curves and zero tolerance for data formats and mistakes when inputting keywords and parameters. To address these problems, this study developed a software package, named the Intelligent Prediction and Association Tool (iPat), with a user-friendly graphical user interface. With iPat, GWAS or GS can be performed using a pointing device to simply drag and/or click on graphical elements to specify input data files, choose input parameters and select analytical models. Models available to users include those implemented in third party CLI packages such as GAPIT, PLINK, FarmCPU, BLINK, rrBLUP and BGLR. Users can choose any data format and conduct analyses with any of these packages. File conversions are automatically conducted for specified input data and selected packages. A GWAS-assisted genomic prediction method was implemented to perform genomic prediction using any GWAS method such as FarmCPU. iPat was written in Java for adaptation to multiple operating systems including Windows, Mac and Linux. The iPat executable file, user manual, tutorials and example datasets are freely available at http://zzlab.net/iPat. zhiwu.zhang@wsu.edu.

PAT-2 (Plutonium Air Transportable Model 2)

International Nuclear Information System (INIS)

Anderson, J.

1981-01-01

The PAT-2 (Plutonium Air Transportable Model 2) package is designed for the safe transport of plutonium and/or uranium in small quantities, especially as used in international safeguards activities, and especially as transported by air. The PAT-2 package is resistant to severe accidents, including that of a high-speed jet aircraft crash, and is designed to withstand such environments as extreme impact, crushing, puncturing and slashing loads, severe hydrocarbon-fueled fires, and deep underwater immersion, with no escape of contents. The accident environments may be imposed upon the package singly or seqentially. The package meets the requirements of 10 CFR 71 for Fissile Class I packages with a cargo of 15 grams of Pu-239, or other isotopic forms described herein, not to exceed 2 watts of thermal activity. Packaging, operational features, and contents of package, are discussed

Enhancing success in transition service coordinators: use of transformational leadership.

Science.gov (United States)

Rearick, Ellen

2007-01-01

The lifespan of children with special healthcare needs has been extended because of improved technology and medical advances. Successful transition to the adult arena of healthcare, social services, and education by adolescents with special healthcare needs (ASHCN) is lacking. The transition service coordinator (TSC) is a multifaceted role of advanced practice nursing that provides highly specialized transition services to adolescents with special healthcare needs. The use of key concepts from the transformational leadership theory may improve healthcare outcomes. This article applies to pediatric and adult primary care and case management services that serve adolescents with special healthcare needs. Employing key concepts of transformational leadership theory will enhance the success of the TSC to improve both collaboration among stakeholders in the transitional team and young adults' transition to the world of adult services. Enhanced communication resulting in improved sharing of information, understanding of the stakeholder roles, and provision of formal linkages between pediatric and adult medical providers is a significant outcome affecting the ASHCN. Improved collaboration will produce a smooth transition for the ASHCN to the world of adult social services education, and employment. Incorporating the transformational leadership dimensions of idealized influence, inspirational motivation intellectual stimulation, and individualized consideration will enhance the ability of the TSC to improve collaboration among stakeholders in the transitional team and the quality of services for the ASHCN.

Best practices in transit service planning : final report, March 2009.

Science.gov (United States)

2009-03-01

The provision of cost efficient and effective bus transit service is the basic premise upon which transit service is developed and the goal that all public transportations agencies strive to achieve. To attain this goal, public transit agencies must ...

Processing of baby food using pressure-assisted thermal sterilization (PATS) and comparison with thermal treatment

Science.gov (United States)

Wang, Yubin; Ismail, Marliya; Farid, Mohammed

2017-10-01

Currently baby food is sterilized using retort processing that gives an extended shelf life. However, this type of heat processing leads to reduction of organoleptic and nutrition value. Alternatively, the combination of pressure and heat could be used to achieve sterilization at reduced temperatures. This study investigates the potential of pressure-assisted thermal sterilization (PATS) technology for baby food sterilization. Here, baby food (apple puree), inoculated with Bacillus subtilis spores was treated using PATS at different operating temperatures, pressures and times and was compared with thermal only treatment. The results revealed that the decimal reduction time of B. subtilis in PATS treatment was lower than that of thermal only treatment. At a similar spore inactivation, the retention of ascorbic acid of PATS-treated sample was higher than that of thermally treated sample. The results indicated that PATS could be a potential technology for baby food processing while minimizing quality deterioration.

Evaluation of the EndoPAT as a Tool to Assess Endothelial Function

Directory of Open Access Journals (Sweden)

M. Moerland

2012-01-01

Endothelial function was stable over a longer period of time in renally impaired patients (coefficient of variation 13%. Endothelial function in renally impaired and type 2 diabetic patients was not decreased compared to healthy volunteers (2.9±1.4 and 1.8±0.3, resp., versus 1.8±0.5, P>0.05. The EndoPAT did not detect an effect of robust interventions on endothelial function in healthy volunteers (glucose load: change from baseline 0.08±0.50, 95% confidence interval −0.44 to 0.60; smoking: change from baseline 0.49±0.92, 95% confidence interval −0.47 to 1.46. This suggests that at present the EndoPAT might not be suitable to assess (changes in endothelial function in early-phase clinical pharmacology studies. Endothelial function as measured by the EndoPAT could be physiologically different from endothelial function as measured by conventional techniques. This should be investigated carefully before the EndoPAT can be considered a useful tool in drug development or clinical practice.

14 CFR 375.50 - Transit flights; scheduled international air service operations.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Transit flights; scheduled international... WITHIN THE UNITED STATES Transit Flights § 375.50 Transit flights; scheduled international air service... to the International Air Services Transit Agreement in transit across the United States may not be...

绚丽秀美，气势迫人 Pat Metheny/Brad Mehldau 《Metheny Mehldau》

Institute of Scientific and Technical Information of China (English)

马其发

2007-01-01

<正>爵士吉他高手Pat Metheny的作品通常"兵分两路",一是以Pat Metheny Group集体创作出碟,玩Crossover Jazz或Fusjon为主;另一是以Pat Metheny名义与一些乐坛名宿合作,玩Contemporary Jazz、Folk Jazz和

Quality-by-Design (QbD): An integrated process analytical technology (PAT) approach for a dynamic pharmaceutical co-precipitation process characterization and process design space development.

Science.gov (United States)

Wu, Huiquan; White, Maury; Khan, Mansoor A

2011-02-28

The aim of this work was to develop an integrated process analytical technology (PAT) approach for a dynamic pharmaceutical co-precipitation process characterization and design space development. A dynamic co-precipitation process by gradually introducing water to the ternary system of naproxen-Eudragit L100-alcohol was monitored at real-time in situ via Lasentec FBRM and PVM. 3D map of count-time-chord length revealed three distinguishable process stages: incubation, transition, and steady-state. The effects of high risk process variables (slurry temperature, stirring rate, and water addition rate) on both derived co-precipitation process rates and final chord-length-distribution were evaluated systematically using a 3(3) full factorial design. Critical process variables were identified via ANOVA for both transition and steady state. General linear models (GLM) were then used for parameter estimation for each critical variable. Clear trends about effects of each critical variable during transition and steady state were found by GLM and were interpreted using fundamental process principles and Nyvlt's transfer model. Neural network models were able to link process variables with response variables at transition and steady state with R(2) of 0.88-0.98. PVM images evidenced nucleation and crystal growth. Contour plots illustrated design space via critical process variables' ranges. It demonstrated the utility of integrated PAT approach for QbD development. Published by Elsevier B.V.

Quantifying Beetle-Mediated Effects on Gas Fluxes from Dung Pats

Science.gov (United States)

Penttilä, Atte; Slade, Eleanor M.; Simojoki, Asko; Riutta, Terhi; Minkkinen, Kari; Roslin, Tomas

2013-01-01

Agriculture is one of the largest contributors of the anthropogenic greenhouse gases (GHGs) responsible for global warming. Measurements of gas fluxes from dung pats suggest that dung is a source of GHGs, but whether these emissions are modified by arthropods has not been studied. A closed chamber system was used to measure the fluxes of carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O) from dung pats with and without dung beetles on a grass sward. The presence of dung beetles significantly affected the fluxes of GHGs from dung pats. Most importantly, fresh dung pats emitted higher amounts of CO2 and lower amounts of CH4 per day in the presence than absence of beetles. Emissions of N2O showed a distinct peak three weeks after the start of the experiment – a pattern detected only in the presence of beetles. When summed over the main grazing season (June–July), total emissions of CH4 proved significantly lower, and total emissions of N2O significantly higher in the presence than absence of beetles. While clearly conditional on the experimental conditions, the patterns observed here reveal a potential impact of dung beetles on gas fluxes realized at a small spatial scale, and thereby suggest that arthropods may have an overall effect on gas fluxes from agriculture. Dissecting the exact mechanisms behind these effects, mapping out the range of conditions under which they occur, and quantifying effect sizes under variable environmental conditions emerge as key priorities for further research. PMID:23940758

Jobs within a 30-minute transit ride - Service

Data.gov (United States)

U.S. Environmental Protection Agency — This mapping service summarizes the total number of jobs that can be reached within 30 minutes by transit. EPA modeled accessibility via transit by calculating total...

Toward Higher QA: From Parametric Release of Sterile Parenteral Products to PAT for Other Pharmaceutical Dosage Forms.

Science.gov (United States)

Hock, Sia Chong; Constance, Neo Xue Rui; Wah, Chan Lai

2012-01-01

Pharmaceutical products are generally subjected to end-product batch testing as a means of quality control. Due to the inherent limitations of conventional batch testing, this is not the most ideal approach for determining the pharmaceutical quality of the finished dosage form. In the case of terminally sterilized parenteral products, the limitations of conventional batch testing have been successfully addressed with the application of parametric release (the release of a product based on control of process parameters instead of batch sterility testing at the end of the manufacturing process). Consequently, there has been an increasing interest in applying parametric release to other pharmaceutical dosage forms, beyond terminally sterilized parenteral products. For parametric release to be possible, manufacturers must be capable of designing quality into the product, monitoring the manufacturing processes, and controlling the quality of intermediates and finished products in real-time. Process analytical technology (PAT) has been thought to be capable of contributing to these prerequisites. It is believed that the appropriate use of PAT tools can eventually lead to the possibility of real-time release of other pharmaceutical dosage forms, by-passing the need for end-product batch testing. Hence, this literature review attempts to present the basic principles of PAT, introduce the various PAT tools that are currently available, present their recent applications to pharmaceutical processing, and explain the potential benefits that PAT can bring to conventional ways of processing and quality assurance of pharmaceutical products. Last but not least, current regulations governing the use of PAT and the manufacturing challenges associated with PAT implementation are also discussed. Pharmaceutical products are generally subjected to end-product batch testing as a means of quality control. Due to the inherent limitations of conventional batch testing, this is not the most

Dynamics of Ecosystem Services during Forest Transitions in Reventazón, Costa Rica.

Science.gov (United States)

Vallet, Améline; Locatelli, Bruno; Levrel, Harold; Brenes Pérez, Christian; Imbach, Pablo; Estrada Carmona, Natalia; Manlay, Raphaël; Oszwald, Johan

2016-01-01

The forest transition framework describes the temporal changes of forest areas with economic development. A first phase of forest contraction is followed by a second phase of expansion once a turning point is reached. This framework does not differentiate forest types or ecosystem services, and describes forests regardless of their contribution to human well-being. For several decades, deforestation in many tropical regions has degraded ecosystem services, such as watershed regulation, while increasing provisioning services from agriculture, for example, food. Forest transitions and expansion have been observed in some countries, but their consequences for ecosystem services are often unclear. We analyzed the implications of forest cover change on ecosystem services in Costa Rica, where a forest transition has been suggested. A review of literature and secondary data on forest and ecosystem services in Costa Rica indicated that forest transition might have led to an ecosystem services transition. We modeled and mapped the changes of selected ecosystem services in the upper part of the Reventazón watershed and analyzed how supply changed over time in order to identify possible transitions in ecosystem services. The modeled changes of ecosystem services is similar to the second phase of a forest transition but no turning point was identified, probably because of the limited temporal scope of the analysis. Trends of provisioning and regulating services and their tradeoffs were opposite in different spatial subunits of our study area, which highlights the importance of scale in the analysis of ecosystem services and forest transitions. The ecosystem services transition framework proposed in this study is useful for analyzing the temporal changes of ecosystem services and linking socio-economic drivers to ecosystem services demand at different scales.

Youth experiences of transition from child mental health services to adult mental health services: a qualitative thematic synthesis.

Science.gov (United States)

Broad, Kathleen L; Sandhu, Vijay K; Sunderji, Nadiya; Charach, Alice

2017-11-28

Adolescence and young adulthood is a vulnerable time during which young people experience many development milestones, as well as an increased incidence of mental illness. During this time, youth also transition between Child and Adolescent Mental Health Services (CAMHS) to Adult Mental Health Services (AMHS). This transition puts many youth at risk of disengagement from service use; however, our understanding of this transition from the perspective of youth is limited. This systematic review aims to provide a more comprehensive understanding of youth experiences of transition from CAMHS to AMHS, through a qualitative thematic synthesis of the extant literature in this area. Published and unpublished literature was searched using keywords targeting three subject areas: Transition, Age and Mental Health. Studies were included if they qualitatively explored the perceptions and experiences of youth who received mental health services in both CAMHS and AMHS. There were no limitations on diagnosis or age of youth. Studies examining youth with chronic physical health conditions were excluded. Eighteen studies, representing 14 datasets and the experiences of 253 unique service-users were included. Youth experiences of moving from CAMHS and AMHS are influenced by concurrent life transitions and their individual preferences regarding autonomy and independence. Youth identified preparation, flexible transition timing, individualized transition plans, and informational continuity as positive factors during transition. Youth also valued joint working and relational continuity between CAMHS and AMHS. Youth experience a dramatic culture shift between CAMHS and AMHS, which can be mitigated by individualized and flexible approaches to transition. Youth have valuable perspectives to guide the intelligent design of mental health services and their perspectives should be used to inform tools to evaluate and incorporate youth perspectives into transitional service improvement

New PAT tools for assessing content uniformity, sampling error, and degree of crystallinity in pharmaceutical tablets

DEFF Research Database (Denmark)

Warnecke, Solveig

of the pharmaceutical drug, both during development and throughout the production. The usage of PAT tools is encouraged by the regulatory authorities, and therefore the interest in new and improved PAT tools is increasing. The main purpose of introducing Quality by Design (QbD) and PAT in pharmaceutical production...... practice in traditional pharmaceutical industry. In this thesis, three spectroscopic PAT tools are investigated, near-infrared-, terahertz-, and fluorescence-spectroscopy. These techniques have been evaluated with chemometrics and theory of sampling. The first study focused on the critical but rather...... overlooked sampling uncertainty that exist in all analytical measurements. The sampling error was studied using an example involving near infrared transmission (NIT) spectroscopy to study content of uniformity of five batches of escitalopram tablets, produced at different active pharmaceutical ingredients...

THz spectroscopy: An emerging technology for pharmaceutical development and pharmaceutical Process Analytical Technology (PAT) applications

Science.gov (United States)

Wu, Huiquan; Khan, Mansoor

2012-08-01

As an emerging technology, THz spectroscopy has gained increasing attention in the pharmaceutical area during the last decade. This attention is due to the fact that (1) it provides a promising alternative approach for in-depth understanding of both intermolecular interaction among pharmaceutical molecules and pharmaceutical product quality attributes; (2) it provides a promising alternative approach for enhanced process understanding of certain pharmaceutical manufacturing processes; and (3) the FDA pharmaceutical quality initiatives, most noticeably, the Process Analytical Technology (PAT) initiative. In this work, the current status and progress made so far on using THz spectroscopy for pharmaceutical development and pharmaceutical PAT applications are reviewed. In the spirit of demonstrating the utility of first principles modeling approach for addressing model validation challenge and reducing unnecessary model validation "burden" for facilitating THz pharmaceutical PAT applications, two scientific case studies based on published THz spectroscopy measurement results are created and discussed. Furthermore, other technical challenges and opportunities associated with adapting THz spectroscopy as a pharmaceutical PAT tool are highlighted.

Comparison of Different Approaches to Predict the Performance of Pumps As Turbines (PATs

Directory of Open Access Journals (Sweden)

Mauro Venturini

2018-04-01

Full Text Available This paper deals with the comparison of different methods which can be used for the prediction of the performance curves of pumps as turbines (PATs. The considered approaches are four, i.e., one physics-based simulation model (“white box” model, two “gray box” models, which integrate theory on turbomachines with specific data correlations, and one “black box” model. More in detail, the modeling approaches are: (1 a physics-based simulation model developed by the same authors, which includes the equations for estimating head, power, and efficiency and uses loss coefficients and specific parameters; (2 a model developed by Derakhshan and Nourbakhsh, which first predicts the best efficiency point of a PAT and then reconstructs their complete characteristic curves by means of two ad hoc equations; (3 the prediction model developed by Singh and Nestmann, which predicts the complete turbine characteristics based on pump shape and size; (4 an Evolutionary Polynomial Regression model, which represents a data-driven hybrid scheme which can be used for identifying the explicit mathematical relationship between PAT and pump curves. All approaches are applied to literature data, relying on both pump and PAT performance curves of head, power, and efficiency over the entire range of operation. The experimental data were provided by Derakhshan and Nourbakhsh for four different turbomachines, working in both pump and PAT mode with specific speed values in the range 1.53–5.82. This paper provides a quantitative assessment of the predictions made by means of the considered approaches and also analyzes consistency from a physical point of view. Advantages and drawbacks of each method are also analyzed and discussed.

Amino acid derivatives are substrates or non-transported inhibitors of the amino acid transporter PAT2 (slc36a2).

Science.gov (United States)

Edwards, Noel; Anderson, Catriona M H; Gatfield, Kelly M; Jevons, Mark P; Ganapathy, Vadivel; Thwaites, David T

2011-01-01

The H(+)-coupled amino acid transporter PAT2 (SLC36A2) transports the amino acids proline, glycine, alanine and hydroxyproline. A physiological role played by PAT2 in amino acid reabsorption in the renal proximal tubule is demonstrated by mutations in SLC36A2 that lead to an iminoglycinuric phenotype (imino acid and glycine uria) in humans. A number of proline, GABA and tryptophan derivatives were examined to determine if they function either as transported substrates or non-transported inhibitors of PAT2. The compounds were investigated following heterologous expression of rat PAT2 in Xenopus laevis oocytes. PAT2 function was characterised by: radiotracer uptake and competition (cis-inhibition) studies; radiotracer efflux and trans-stimulation; and measurement of substrate-induced positive inward current by two-electrode voltage-clamp. In general, the proline derivatives appeared to be transported substrates and the relative ability to induce current flow was closely related to the inhibitory effects on PAT2-mediated l-[(3)H]proline uptake. In contrast, certain heterocyclic GABA derivatives (e.g. l-pipecolic acid) were translocated only slowly. Finally, the tryptophan derivatives inhibited PAT2 function but did not undergo transport. l-Proline uptake was inhibited by 5-hydroxy-l-tryptophan (IC(50) 1.6±0.4mM), α-methyl-d,l-tryptophan (3.5±1.5mM), l-tryptophan, 1-methyl-l-tryptophan and indole-3-propionic acid. Although neither 5-hydroxy-l-tryptophan nor α-methyl-d,l-tryptophan were able to elicit inward current in PAT2-expressing oocytes both reduced the current evoked by l-proline. 5-Hydroxy-l-tryptophan and α-methyl-d,l-tryptophan were unable to trans-stimulate l-proline efflux from PAT2-expressing oocytes, confirming that the two compounds act as non-transported blockers of PAT2. These two tryptophan derivatives should prove valuable experimental tools in future investigations of the physiological roles of PAT2. Copyright © 2010 Elsevier B.V. All rights

PAT-2 (Plutonium Air-Transportable Model 2) safety analysis report

International Nuclear Information System (INIS)

Andersen, J.A.; Davis, E.J.; Duffey, T.A.; Dupree, S.A.; George, O.L. Jr.; Ortiz, Z.

1981-07-01

The PAT-2 package is designed for the safe transport of plutonium and/or uranium in small quantities. The PAT-2 package is resistant to severe accidents, including that of a high-speed jet aircraft crash, and is designed to withstand such environments as extreme impact, crushing, puncturing and slashing loads, severe hydrocarbon-fueled fires, and deep underwater immersion, with no escape of contents. The package meets the requirements of 10 CFR 71 for Fissile Class I packages with a cargo of 15 grams of Pu-239, or other isotopic forms described herein, not to exceed 2 watts of thermal activity. This SAR presents design and oprational information including evaluations and analyses, test results, operating procedures, maintenance, and quality assurance information

PAT-2 (Plutonium Air-Transportable Model 2) safety analysis report

Energy Technology Data Exchange (ETDEWEB)

Andersen, J.A.; Davis, E.J.; Duffey, T.A.; Dupree, S.A.; George, O.L. Jr.; Ortiz, Z.

1981-07-01

The PAT-2 package is designed for the safe transport of plutonium and/or uranium in small quantities. The PAT-2 package is resistant to severe accidents, including that of a high-speed jet aircraft crash, and is designed to withstand such environments as extreme impact, crushing, puncturing and slashing loads, severe hydrocarbon-fueled fires, and deep underwater immersion, with no escape of contents. The package meets the requirements of 10 CFR 71 for Fissile Class I packages with a cargo of 15 grams of Pu-239, or other isotopic forms described herein, not to exceed 2 watts of thermal activity. This SAR presents design and oprational information including evaluations and analyses, test results, operating procedures, maintenance, and quality assurance information.

Transitions between child and adult mental health services: service design, philosophy and meaning at uncertain times.

Science.gov (United States)

Murcott, W J

2014-09-01

A young person's transition of care from child and adolescent mental health services to adult mental health services can be an uncertain and distressing event that can have serious ramifications for their recovery. Recognition of this across many countries and recent UK media interest in the dangers of mental health services failing young people has led practitioners to question the existing processes. This paper reviews the current theories and research into potential failings of services and encourages exploration for a deeper understanding of when and how care should be managed in the transition process for young people. Mental health nurses can play a vital role in this process and, by adopting the assumptions of this paradigm, look at transition from this unique perspective. By reviewing the current ideas related to age boundaries, service thresholds, service philosophy and service design, it is argued that the importance of the therapeutic relationship, the understanding of the cultural context of the young person and the placing of the young person in a position of autonomy and control should be central to any decision and process of transfer between two mental health services. © 2014 John Wiley & Sons Ltd.

The effects of PAT on the Savannah River ecosystem, particularly fisheries

Energy Technology Data Exchange (ETDEWEB)

Patrick, R.

1994-03-01

The main purpose of this study was to determine whether or not the pre-startup activities at K-Reactor, i.e., Power Ascension Testing (PAT), have caused damage because of temperature rises in the Savannah River. Therefore, the biological studies were mainly aimed at providing information as to changes that might cause the damage of the fish population, and to other important organisms in the ecosystem. To determine if deleterious effects had occurred, one had to review the past studies to determine the condition and diversity of aquatic life before these PAT studies started. Therefore old reports were reviewed and a current study made in 1992.

Service Learning as a Transition into Foundation Field

Directory of Open Access Journals (Sweden)

Nancy P. Kropf

2002-05-01

Full Text Available Service learning is a pedagogical method to bridge classroom and community experiences for students. Although social work education has historically emphasized this connection through internship experiences, service learning can fill a different function within the curriculum. This article proposes a service learning experience to assist graduate students with the transition into their foundation field placement. Beneficial outcomes of using service learning as an educational bridge are discussed for students, faculty, and the social work program.

Photon activated therapy (PAT) using monochromatic synchrotron X-rays and iron oxide nanoparticles in a mouse tumor model: feasibility study of PAT for the treatment of superficial malignancy.

Science.gov (United States)

Choi, Gi-Hwan; Seo, Seung-Jun; Kim, Ki-Hong; Kim, Hong-Tae; Park, Sung-Hwan; Lim, Jae-Hong; Kim, Jong-Ki

2012-10-31

X-rays are known to interact with metallic nanoparticles, producing photoelectric species as radiosensitizing effects, and have been exploited in vivo mainly with gold nanoparticles. The purpose of this study was to investigate the potential of sensitizing effect of iron oxide nanoparticles for photon activated therapy. X-rays photon activated therapy (PAT) was studied by treating CT26 tumor cells and CT26 tumor-bearing mice loaded with 13-nm diameter FeO NP, and irradiating them at 7.1 keV near the Fe K-edge using synchrotron x-rays radiation. Survival of cells was determined by MTT assay, and tumor regression assay was performed for in vivo model experiment. The results of PAT treated groups were compared with x-rays alone control groups. A more significant reduction in viability and damage was observed in the FeO NP-treated irradiated cells, compared to the radiation alone group (p X-rays. Since 7.1 keV X-rays is attenuated very sharply in the tissue, FeO NP-PAT may have promise as a potent treatment option for superficial malignancies in the skin, like chest wall recurrence of breast cancer.

Promoting School Psychologist Participation in Transition Services Using the TPIE Model

Science.gov (United States)

Talapatra, Devadrita; Roach, Andrew T.; Varjas, Kris; Houchins, David E.; Crimmins, Daniel B.

2018-01-01

Transition services can be used to forge family, school, and community partnerships and foster a successful shift to adult life for students with intellectual disabilities (ID). School psychologists can play a valuable additive role in supporting the transition process due to their graduate training in interpersonal skills; consultation services;…

Ion Storage Tests with the High Performance Antimatter Trap (HiPAT)

Science.gov (United States)

Martin, James J.; Lewis, Raymond A.; Chakrabarti, Suman; Pearson, Boise; Schafer, Charles (Technical Monitor)

2002-01-01

The NASA/Marshall Space Flight Centers (NASA/MSFC) Propulsion Research Center (PRC) is evaluating an antiproton storage system, referred to as the High Performance Antiproton Trap (HiPAT). This interest stems from the sheer energy represented by matter/antimatter annihilation process with has an energy density approximately 10 order of magnitude above that of chemical propellants. In other terms, one gram of antiprotons contains the equivalent energy of approximately 23 space shuttle external tanks or ET's (each ET contains roughly 740,000 kgs of fuel and oxidizer). This incredible source of stored energy, if harnessed, would be an enabling technology for deep space mission where both spacecraft weight and propulsion performance are key to satisfying aggressive mission requirements. The HiPAT hardware consists of a 4 Tesla superconductor system, an ultra high vacuum test section (vacuum approaching 10(exp -12) torr), and a high voltage confinement electrode system (up to 20 kvolts operation). The current laboratory layout is illustrated. The HiPAT designed objectives included storage of up to 1 trillion antiprotons with corresponding lifetimes approaching 18 days. To date, testing has centered on the storage of positive hydrogen ions produced in situ by a stream of high-energy electrons that passes through the trapping region. However, due to space charge issues and electron beam compression as it passes through the HiPAT central field, current ion production is limited to less then 50,000 ions. Ion lifetime was determined by counting particle populations at the end of various storage time intervals. Particle detection was accomplished by destructively expelling the ions against a micro-channel plate located just outside the traps magnetic field. The effect of radio frequency (RF) stabilization on the lifetime of trapped particles was also examined. This technique, referred to as a rotating wall, made use of a segmented electrode located near the center of the trap

Expression of PAT and NPT II proteins during the developmental stages of a genetically modified pepper developed in Korea.

Science.gov (United States)

Kim, Hyo Jin; Lee, Si Myung; Kim, Jae Kwang; Ryu, Tae Hun; Suh, Seok Cheol; Cho, Hyun Suk

2010-10-27

Estimation of the protein levels introduced in a biotechnology-derived product is conducted as part of an overall safety assessment. An enzyme-linked immunosorbent assay (ELISA) was used to analyze phosphinothricin acetyltransferase (PAT) and neomycin phosphotransferase II (NPT II) protein expression in a genetically modified (GM) pepper plant developed in Korea. PAT and NPT II expression levels, based on both dry weight and fresh weight, were variable among different plant generations and plant sections from isolated genetically modified organism (GMO) fields at four developmental stages. PAT expression was highest in leaves at anthesis (11.44 μg/gdw and 2.17 μg/gfw) and lowest in roots (0.12 μg/gdw and 0.01 μg/gfw). NPT II expression was also highest in leaves at anthesis (17.31 μg/gdw and 3.41 μg/gfw) and lowest in red pepper (0.65 μg/gdw and 0.12 μg/gfw). In pollen, PAT expression was 0.59-0.62 μg/gdw, while NPT II was not detected. Both PAT and NPT II showed a general pattern of decreased expression with progression of the growing season. As expected, PAT and NPT II protein expression was not detectable in control pepper plants.

Patērētāju attieksme pret zīmolu "IKEA"

OpenAIRE

Aleksejenko, Dana

2014-01-01

Tēma ir “Patērētāju attieksme pret zīmolu “IKEA””.Pētījuma mērķis ir noskaidrot Latvijas iedzīvotāju, “IKEA” zīmola patērētāju un mazumtirgotāju viedokli, attieksmi un vērtējumu par zīmolu “IKEA”.Radošā daļa ir pamatota ar teorētisko daļu par:zīmola jēdzienu, patērētāju uzvedību, mārketinga komunikāciju un uzņēmumu internetā. Apakašnodaļās ir aprakstīta zīmola identitāte un zīmola vērtība, korporatīvais zīmols un korporatīvā identitāte.Metodoloģija ir izstrādāta vairākās pakāpēs,katras pakāpe...

Pharmacist Advancement of Transitions of Care to Home (PATCH) Service.

Science.gov (United States)

Trang, Joseph; Martinez, Amanda; Aslam, Sadaf; Duong, Minh-Tri

2015-11-01

There is a paucity of literature on a well-defined role of a pharmacist in different aspects of transition of care service (TCS). Although health care institutions have specific details on the discharge process, there is a need for a sustainable TCS with a well-defined role of pharmacists. To describe the impact of a pharmacist-led TCS on acute health care utilization, clinic quality indicators, and identification and resolution of medication-related problems (MRPs). A pharmacist-managed TCS service, referred to as the Pharmacist Advancement of Transitions of Care to Home (PATCH) service, was established at an academic medical center, where high-risk patients received a postdischarge phone call from a pharmacist followed by a face-to-face meeting with the pharmacist and the patient's primary care provider (PCP). In a prospective transitions of care group (n = 74), outcomes of patients such as acute health care utilization (an emergency department visit or an inpatient readmission, within 30 days post discharge), clinic quality indicators, and identification and resolution of MRPs were compared to a retrospective control group (n = 87) who received the standard of care. Utilization of acute health care services was significantly lower in the prospective group compared to the retrospective control group (23% vs 41.4%; P = .013). A total of 49 MRPs were discovered in patients who received the TCS. Pharmacists play an integral role in improving the transitions of care to reduce acute health care utilization. In addition, they may improve care transitions by optimizing clinic quality indicators and by identifying and resolving MRPs.

Multivariate PAT solutions for biopharmaceutical cultivation: current progress and limitations

NARCIS (Netherlands)

Mercier, S.M.; Diepenbroek, B.; Wijffels, R.H.; Streefland, M.

2014-01-01

Increasingly elaborate and voluminous datasets are generated by the (bio)pharmaceutical industry and are a major challenge for application of PAT and QbD principles. Multivariate data analysis (MVDA) is required to delineate relevant process information from large multi-factorial and multi-collinear

PATs Operating in Water Networks under Unsteady Flow Conditions: Control Valve Manoeuvre and Overspeed Effect

Directory of Open Access Journals (Sweden)

Modesto Pérez-Sánchez

2018-04-01

Full Text Available The knowledge of transient conditions in water pressurized networks equipped with pump as turbines (PATs is of the utmost importance and necessary for the design and correct implementation of these new renewable solutions. This research characterizes the water hammer phenomenon in the design of PAT systems, emphasizing the transient events that can occur during a normal operation. This is based on project concerns towards a stable and efficient operation associated with the normal dynamic behaviour of flow control valve closure or by the induced overspeed effect. Basic concepts of mathematical modelling, characterization of control valve behaviour, damping effects in the wave propagation and runaway conditions of PATs are currently related to an inadequate design. The precise evaluation of basic operating rules depends upon the system and component type, as well as the required safety level during each operation.

Greenhouse gas emissions from dung pats vary with dung beetle species and with assemblage composition.

Directory of Open Access Journals (Sweden)

Irene Piccini

Full Text Available Cattle farming is a major source of greenhouse gases (GHGs. Recent research suggests that GHG fluxes from dung pats could be affected by biotic interactions involving dung beetles. Whether and how these effects vary among beetle species and with assemblage composition is yet to be established. To examine the link between GHGs and different dung beetle species assemblages, we used a closed chamber system to measure fluxes of carbon dioxide (CO2, methane (CH4 and nitrous oxide (N2O from cattle dung pats. Targeting a total of four dung beetle species (a pat-dwelling species, a roller of dung balls, a large and a small tunnelling species, we ran six experimental treatments (four monospecific and two mixed and two controls (one with dung but without beetles, and one with neither dung nor beetles. In this setting, the overall presence of beetles significantly affected the gas fluxes, but different species contributed unequally to GHG emissions. When compared to the control with dung, we detected an overall reduction in the total cumulative CO2 flux from all treatments with beetles and a reduction in N2O flux from the treatments with the three most abundant dung beetle species. These reductions can be seen as beneficial ecosystem services. Nonetheless, we also observed a disservice provided by the large tunneler, Copris lunaris, which significantly increased the CH4 flux-an effect potentially traceable to the species' nesting strategy involving the construction of large brood balls. When fluxes were summed into CO2-equivalents across individual GHG compounds, dung with beetles proved to emit less GHGs than did beetle-free dung, with the mix of the three most abundant species providing the highest reduction (-32%. As the mix of multiple species proved the most effective in reducing CO2-equivalents, the conservation of diverse assemblages of dung beetles emerges as a priority in agro-pastoral ecosystems.

Transit's leading edge : innovations in service and technology : issue paper 7

Energy Technology Data Exchange (ETDEWEB)

NONE

2003-11-01

The Canadian Urban Transit Association is committed to raising awareness of the social, environmental and economic benefits of mass transit systems. Innovation is needed to address the challenges of attracting new riders, resolving fiscal imbalances, and meeting environmental concerns. This issue paper presents examples of how Canada's transit industry has used innovation to address the issue of climate change and fight smog. It includes a brief description of some of the ways that Canadian transit suppliers and transit systems are going green: Canada's bus builders are developing hybrid buses; Grand River Transit is improving air quality with clean diesel; Montreal's Transit Society is reducing emissions with biodiesel buses; Saskatoon Transit Service is using biodiesel buses; Laval's Transit Society is listening to customer complaints in an effort to reduce response times and improve customer service; Canadian Urban Transit Association is improving customer service; Transit Windsor is promoting a smog solution; Winnipeg Transit is working with employers to boost ridership; Trapeze Software Group is providing customers with quick and accurate trip itineraries; St. John's Transportation Commission has added solar-powered, light emitting diode illumination to bus stops; the City of Ottawa has an established transit priority measures; and, Infodev EDI Inc. has supplied automated high-technology solutions for passenger counting and vehicle location tracking to several Canadian transit systems. refs., figs.

Service Design Outcomes in Finnish Book Industry : From Transition to Transformation

OpenAIRE

Nousiainen, Anu K.

2013-01-01

Service Design Outcomes in Finnish Book Industry - From Transition to Transformation Book industry is in transition especially due to technology advancements, converging operational environment and evolving consumer values and practices in the digital context. Simultaneously, the post-industrial paradigm shift from products to services, systems and experiences highlights the intangibles-driven economy, where existing value chain members need to find new directions and new business oppo...

Patógenos introducidos al Perú en post larvas de Litopenaeus vannamei importadas

Directory of Open Access Journals (Sweden)

Mervin Guevara

2012-11-01

Full Text Available El comercio internacional de animales acuáticos es uno de los factores más importantes en la introducción involuntaria de patógenos a una región libre de estos. Los patógenos introducidos han sido causa de enormes pérdidas económicas en organismos bajo cultivo y daños ecológicos en poblaciones silvestres. En este trabajo, utilizando la técnica de la PCR se analizaron postlarvas de Litopenaeus vannamei importadas desde Ecuador para ser utilizada en los cultivos de langostinos en Tumbes. La finalidad fue detectar patógenos como el virus de la mancha blanca (WSV, virus de la cabeza amarilla (YHV, virus de la necrosis hipodérmica y hematopoyética infecciosa (IHHNV, Baculovirus penaei (BP, virus del síndrome de Taura (TSV y la bacteria de la hepatopancreatitis necrotizante (NHPB. Se analizaron 177 muestras de postlarvas en el año 2009 y 274 en el 2010. En el año 2009 se encontraron cuatro patógenos infecciosos en las postlarvas analizadas, siendo más frecuente el IHHNV (9,60%. En el año 2010 la frecuencia de aparición de postlarvas infectadas con IHHNV fue mayor (16,79%. Tanto en el 2009 como en el 2010 se encontraron postlarvas positivas a NHPB, BP y TSV

Remote sensing, geographical information systems, and spatial modeling for analyzing public transit services

Science.gov (United States)

Wu, Changshan

Public transit service is a promising transportation mode because of its potential to address urban sustainability. Current ridership of public transit, however, is very low in most urban regions, particularly those in the United States. This woeful transit ridership can be attributed to many factors, among which poor service quality is key. Given this, there is a need for transit planning and analysis to improve service quality. Traditionally, spatially aggregate data are utilized in transit analysis and planning. Examples include data associated with the census, zip codes, states, etc. Few studies, however, address the influences of spatially aggregate data on transit planning results. In this research, previous studies in transit planning that use spatially aggregate data are reviewed. Next, problems associated with the utilization of aggregate data, the so-called modifiable areal unit problem (MAUP), are detailed and the need for fine resolution data to support public transit planning is argued. Fine resolution data is generated using intelligent interpolation techniques with the help of remote sensing imagery. In particular, impervious surface fraction, an important socio-economic indicator, is estimated through a fully constrained linear spectral mixture model using Landsat Enhanced Thematic Mapper Plus (ETM+) data within the metropolitan area of Columbus, Ohio in the United States. Four endmembers, low albedo, high albedo, vegetation, and soil are selected to model heterogeneous urban land cover. Impervious surface fraction is estimated by analyzing low and high albedo endmembers. With the derived impervious surface fraction, three spatial interpolation methods, spatial regression, dasymetric mapping, and cokriging, are developed to interpolate detailed population density. Results suggest that cokriging applied to impervious surface is a better alternative for estimating fine resolution population density. With the derived fine resolution data, a multiple

Improving care planning and coordination for service users with medical co-morbidity transitioning between tertiary medical and primary care services.

Science.gov (United States)

Cranwell, K; Polacsek, M; McCann, T V

2017-08-01

WHAT IS KNOWN ON THE SUBJECT?: Mental health service users with medical co-morbidity frequently experience difficulties accessing and receiving appropriate treatment in emergency departments. Service users frequently experience fragmented care planning and coordinating between tertiary medical and primary care services. Little is known about mental health nurses' perspectives about how to address these problems. WHAT THIS PAPER ADDS TO EXISTING KNOWLEDGE?: Emergency department clinicians' poor communication and negative attitudes have adverse effects on service users and the quality of care they receive. The findings contribute to the international evidence about mental health nurses' perspectives of service users feeling confused and frustrated in this situation, and improving coordination and continuity of care, facilitating transitions and increasing family and caregiver participation. Intervention studies are needed to evaluate if adoption of these measures leads to sustainable improvements in care planning and coordination, and how service users with medical co-morbidity are treated in emergency departments in particular. WHAT ARE THE IMPLICATIONS FOR PRACTICE?: Effective planning and coordination of care are essential to enable smooth transitions between tertiary medical (emergency departments in particular) and primary care services for service users with medical co-morbidity. Ongoing professional development education and support is needed for emergency department clinicians. There is also a need to develop an organized and systemic approach to improving service users' experience in emergency departments. Introduction Mental health service users with medical co-morbidity frequently experience difficulties accessing appropriate treatment in medical hospitals, and often there is poor collaboration within and between services. Little is known about mental health nurses' perspectives on how to address these problems. Aim To explore mental health nurses

'Mind the gap'--mapping services for young people with ADHD transitioning from child to adult mental health services.

Science.gov (United States)

Hall, Charlotte L; Newell, Karen; Taylor, John; Sayal, Kapil; Swift, Katie D; Hollis, Chris

2013-07-10

Once considered to be a disorder restricted to childhood, Attention Deficit/Hyperactivity Disorder (ADHD) is now recognised to persist into adult life. However, service provision for adults with ADHD is limited. Additionally, there is little guidance or research on how best to transition young people with ADHD from child to adult services. We report the findings of a survey of 96 healthcare professionals working in children's (Child and Adolescent Mental Health Services and Community Paediatrics) and adult services across five NHS Trusts within the East Midlands region of England to gain a better understanding of the current provision of services for young people with ADHD transitioning into adult mental health services. Our findings indicate a lack of structured guidelines on transitioning and little communication between child and adult services. Child and adult services had differing opinions on what they felt adult services should provide for ADHD cases. Adult services reported feeling ill-prepared to deal with ADHD patients, with clinicians in these services citing a lack of specific knowledge of ADHD and a paucity of resources to deal with such cases. We discuss suggestions for further research, including the need to map the national provision of services for adults with ADHD, and provide recommendations for commissioned adult ADHD services. We specifically advocate an increase in ADHD-specific training for clinicians in adult services, the development of specialist adult ADHD clinics and greater involvement of Primary Care to support the work of generic adult mental health services in adult ADHD management.

Intestinal drug transport via the proton-coupled amino acid transporter PAT1 (SLC36A1) is inhibited by Gly-X(aa) dipeptides

DEFF Research Database (Denmark)

Frølund, Sidsel; Langthaler, Louise; Kall, Morten A

2012-01-01

-Sar as substrates of the amino acid transporter PAT1. The aim of the present study is to investigate if other Gly-containing dipeptides interact with PAT1, and whether they can inhibit PAT1 mediated drug absorption, in vitro and in vivo. The in vitro methods included two-electrode voltage clamp measurements on h...... of different dipeptides. The in vivo part consisted of a pharmacokinetic study in rats following oral administration of gaboxadol and preadministration of 200 mg/kg dipeptide. The results showed that in hPAT1 expressing oocytes Gly-Tyr, Gly-Pro, and Gly-Phe inhibited currents induced by drug substances......, the present study identifies selected dipeptides as inhibitors of PAT1 mediated drug absorption in various in vitro models....

PAT1 (SLC36A1) shows nuclear localization and affect growth of smooth muscle cells from rats

DEFF Research Database (Denmark)

Jensen, Anne; Figueiredo-Larsen, Evan Manuel; Holm, René

2014-01-01

The proton-coupled amino acid transporter 1 (PAT1) is a transporter of amino acids in small intestinal enterocytes. PAT1 is, however, also capable of regulating cell growth and sensing the availability of amino acids in other cell types. The aim of the present study was to investigate the localiz...

Austenitic stainless steel-to-ferritic steel transition joint welding for elevated temperature service

International Nuclear Information System (INIS)

King, J.F.; Goodwin, G.M.; Slaughter, G.M.

1978-01-01

Transition weld joints between ferritic steels and austenitic stainless steels are required for fossil-fired power plants and proposed nuclear plants. The experience with these dissimilar-metal transition joints has been generally satisfactory, but an increasing number of failures of these joints is occurring prematurely in service. These concerns with transition joint service history prompted a program to develop more reliable joints for application in proposed nuclear power plants

PAT portable appliance testing

CERN Document Server

2011-01-01

The Electricity at Work Regulations 1989 require any electrical system to be constructed, maintained and used in such a manner as to prevent danger. This means that inspection and testing of systems, including portable appliances, is needed in order to determine if maintenance is required.This book explains in clear language what needs to be done and includes expert advice on legislation as well as actual testing. The book contains an appendix providing the electrical fundamentals needed by non-specialists and also has sample questions (with answers) for the C&G 2377 exam that anyone who conducts this work is required to take by law.It is an affordable and handy reference for electricians who administer PAT. It is also an ideal refesher and revision guide for the non-specialist, such as maintenance staff, caretakers and charity shop volunteers who carry out these tasks part-time, alongside their many other duties.Brian Scaddan, I Eng, MIET, is a consultant for and an Honorary Member of City & Guilds. ...

Cobre antimicrobiano contra patógenos intrahospitalarios en Perú

Directory of Open Access Journals (Sweden)

Edwin Neciosup

2015-01-01

Full Text Available Introducción: Las infecciones intrahospitalarias (IIH constituyen un problema de salud pública que generan grandes gastos por parte de los gobiernos, debido a que los patógenos causantes de IIH presentan resistencia a fármacos y generan una mayor permanencia de los pacientes, pues la infraestructura hospitalaria constituye un reservorio favorable para los patógenos. Las superficies de cobre surgen como opción sanitaria y efectiva para controlar el crecimiento y propagación de estos patógenos. Objetivos: Evaluar la actividad bactericida de las superficies de cobre contra los principales bacterias patógenas causantes de IIH (Escherichia coli, Pseudomonas aeruginosa y Staphylococcus aureus. Diseño: Estudio experimental con muestreo no probabilístico. Lugar: Hospital Regional Docente las Mercedes (HRDLM y Hospital Provincial Docente Belén (HPDB, Lambayeque, Perú. Materiales: Nueve cepas bacterianas, 3 de E. coli , 3 de P. aeruginosa y 3 de S. aureus; superficies metálicas (1 cm² de cobre y acero inoxidable (control . Intervenciones: Las 9 cepas bacterianas fueron proporcionadas por los hospitales HRDLM (4 cepas y HPDB (5 cepas. Los análisis de ANOVA y de Tukey fueron aplicados para evaluar la actividad bactericida de las superficies de cobre y acero inoxidable contra las 9 cepas causantes de IIH, usando los programas estadísticos Minitab y Sigmaplot, respectivamente. Principales medidas de resultados: Diferencias en el crecimiento bacteriano sobre superficies de cobre o acero inoxidable, con respecto al tiempo de exposición. Resultados: Las 9 cepas -3 de P. aeruginosa, 3 de E. coli y 3 de S. aureus - expuestas a superficies de cobre fueron eliminadas en 10, 15 y 60 minutos, respectivamente. La carga bacteriana de las células expuestas en superficies de acero inoxidable permaneció constante y viable por periodos mayores a 60 minutos. Además, las superficies de cobre eliminaron más rápido a las bacterias Gram negativas (P

At-line process analytical technology (PAT) for more efficient scale up of biopharmaceutical microfiltration unit operations.

Science.gov (United States)

Watson, Douglas S; Kerchner, Kristi R; Gant, Sean S; Pedersen, Joseph W; Hamburger, James B; Ortigosa, Allison D; Potgieter, Thomas I

2016-01-01

Tangential flow microfiltration (MF) is a cost-effective and robust bioprocess separation technique, but successful full scale implementation is hindered by the empirical, trial-and-error nature of scale-up. We present an integrated approach leveraging at-line process analytical technology (PAT) and mass balance based modeling to de-risk MF scale-up. Chromatography-based PAT was employed to improve the consistency of an MF step that had been a bottleneck in the process used to manufacture a therapeutic protein. A 10-min reverse phase ultra high performance liquid chromatography (RP-UPLC) assay was developed to provide at-line monitoring of protein concentration. The method was successfully validated and method performance was comparable to previously validated methods. The PAT tool revealed areas of divergence from a mass balance-based model, highlighting specific opportunities for process improvement. Adjustment of appropriate process controls led to improved operability and significantly increased yield, providing a successful example of PAT deployment in the downstream purification of a therapeutic protein. The general approach presented here should be broadly applicable to reduce risk during scale-up of filtration processes and should be suitable for feed-forward and feed-back process control. © 2015 American Institute of Chemical Engineers.

The relationship between young people's transit use and their perceptions of equity concepts in transit service provision

DEFF Research Database (Denmark)

Kaplan, Sigal; de Abreu e Silva, João; Di Ciommo, Floridea

2014-01-01

This study investigates the effect of price and travel mode fairness and spatial equity in transit provision on the perceived transit service quality, willingness to pay, and habitual frequency of use. Based on the theory of planned behavior, we developed a web-based questionnaire for revealed...

Youth with special health care needs: transition to adult health care services.

Science.gov (United States)

Oswald, Donald P; Gilles, Donna L; Cannady, Mariel S; Wenzel, Donna B; Willis, Janet H; Bodurtha, Joann N

2013-12-01

Transition to adult services for children and youth with special health care needs (CYSHCN) has emerged as an important event in the life course of individuals with disabilities. Issues that interfere with efficient transition to adult health care include the perspectives of stakeholders, age limits on pediatric service, complexity of health conditions, a lack of experienced healthcare professionals in the adult arena, and health care financing for chronic and complex conditions. The purposes of this study were to develop a definition of successful transition and to identify determinants that were associated with a successful transition. The 2007 Survey of Adult Transition and Health dataset was used to select variables to be considered for defining success and for identifying predictors of success. The results showed that a small percentage of young adults who participated in the 2007 survey had experienced a successful transition from their pediatric care.

PAT and SEM study of porous silicon formed by anodization methods

International Nuclear Information System (INIS)

Liu Jian; Wei Long; Wang Huiyao; Ma Chuangxin; Wang Baoyi

2000-01-01

The porous silicon formed by anodization of crystal silicon was studied by positron annihilation technique (PAT) and scanning electron microscopy (SEM). The PAT experiments showed that the mean life and vacancy defects increased with the increasing anodization time. While the intensities of the longest lifetime, several ns-tens ns (ortho-positronium) dropped down. Small single-crystal Si spheres with mean radius of a few μm were observed by SEM after anodization. Pits with mean radius of a few μm from the divorcement of single-crystal spheres were also observed after further anodization. The increases of vacancy defects might be that the extension of structures of porous silicon towards inner layer with anodization time and caused more vacancy defects in inner layer. The SEM observation presented another possibility of the increase of density of vacancy defects in surface layer induced by the change of structures

Changes in Service and Associated Ridership Impacts near a New Light Rail Transit Line

Directory of Open Access Journals (Sweden)

Jeongwoo Lee

2017-10-01

Full Text Available Los Angeles (LA, for many years a city with limited rail transit, is substantially expanding its public transit system. This paradigm change in transportation policy and investment creates new requirements for monitoring. One area needing evaluation is whether new, high quality transit options, such as light rail, near existing transit services increase sustainable transportation mode shares and reduce car travel. Few studies have explored light rail’s role as a catalyst to increase overall transit use and achieve sustainability goals within an auto-oriented city like LA. Metro’s data show that trips taken on its bus and rail system dropped overall by 10.5% between 2009 and 2016, but its rail ridership grew 21% during the same period due to the debut of the Gold Line and Expo Line extensions. We analyze changes to bus service and associated ridership impacts that resulted from the opening of these two LRT lines in LA. The immediate effect of the city’s bus service changes along the Gold Line light rail extension appear to be associated with a net “bus plus rail” ridership decline in that corridor. In contrast, the Expo Line corridor experienced an initial increase in ridership during the two years immediately after its opening, possibly because the bus service was not reduced by the same magnitude as along the Gold Line extension. Our findings indicate that changes in bus service made to coincide with the introduction of new light rail transit (LRT can negatively affect the overall transit ridership in the corridor. Planners and policy makers should closely monitor changes in bus service and ridership associated with new rail transit to ensure investments results in an overall net increase in more sustainable travel.

Mecanismos de defensa en las interacciones planta-patógeno

DEFF Research Database (Denmark)

Madriz-Ordeñana, Kenneth

1998-01-01

ésto. Las in- teracciones planta-patógeno pueden presentar varios tipos de asociaciones, que dependen en gran parte del contenido genético de cada organismo. La resistencia inducida es una forma de defensa activa que involucra la expresión diferencial de genes y cambios metabólicos que ocurren como...

The modest environmental relief resulting from the transition to a service economy

International Nuclear Information System (INIS)

Henriques, Sofia Teives; Kander, Astrid

2010-01-01

A service transition is supposed to lead to the decline of energy intensity (energy/GDP). We argue that this interpretation is overly optimistic because the shift to a service economy is somewhat of an illusion in terms of real production. Several recent studies of structural effects on energy intensity have made the error of using sector shares in current prices, combined with GDP in constant prices, which is inconsistent and ignores the different behaviour of prices across sectors. We use the more correct method of sector shares in constant prices, and make an attempt to single out the effect from the real service transition by using two complementary methods: shift share analyses in current and constant prices, and Logarithmic Mean Divisia Index (LMDI) for 10 developed and 3 emerging economies. A service transition is rather modest in real terms. The major driver of the decline in energy intensity rests within the manufacturing sector. Meanwhile, the transition to a service sector had a small downward impact on energy intensity in 7 of the developed countries (and no impact in the others). For emerging economies like Brazil, Mexico and India, it is the residential sector that drives energy intensity down because of the declining share of this sector as the formal economy grows, and as a consequence of switching to more efficient fuels. (author)

Assessing Transition Service for Handicapped Youth: A Cooperative Interagency Approach.

Science.gov (United States)

Stodden, Robert A.; Boone, Rosalie

1987-01-01

The article presents a cooperative interagency approach for assessing effectiveness of programs and services to facilitate the transition of handicapped students from school to adult community living. Features of the model include cooperative planning at the policy level, implementation level, and direct service level; and collaboration by state…

Genetic mental services for retardation. patIents with seve.re

African Journals Online (AJOL)

1982-01-04

Jan 4, 1982 ... Care of Mentally Deficient Persons in the RSA (1967) dermed persons with mental .... hensive genetic service for patients with mental retardation and ..... servIces. There are numerous homes and institutions for the mentally.

Crystallization and preliminary X-ray diffraction analysis of PAT, an acetyltransferase from Sulfolobus solfataricus

International Nuclear Information System (INIS)

Cho, Ching-Chang; Luo, Ching-Wei; Hsu, Chun-Hua

2008-01-01

PAT, an acetyltransferase from the archaeon S. solfataricus that specifically acetylates the chromatin protein Alba, was expressed, purified and crystallized. PAT is an acetyltransferase from the archaeon Sulfolobus solfataricus that specifically acetylates the chromatin protein Alba. The enzyme was expressed, purified and subsequently crystallized using the sitting-drop vapour-diffusion technique. Native diffraction data were collected to 1.70 Å resolution on the BL13C1 beamline of NSRRC from a flash-frozen crystal at 100 K. The crystals belonged to space group P2 1 2 1 2 1 , with unit-cell parameters a = 44.30, b = 46.59, c = 68.39 Å

CFD Modelling of a Pump as Turbine (PAT with Rounded Leading Edge Impellers for Micro Hydro Systems

Directory of Open Access Journals (Sweden)

Ismail Mohd Azlan

2017-01-01

Full Text Available A Pump as Turbine (PAT is one of micro hydro system components that is used to substitute a commercially available turbine due to its wide availability and low acquisition cost. However, PAT have high hydraulic losses due to differences in pump-turbine operation and hydraulic design. The fluid flowing inside the PAT is subjected to hydraulic losses due to the longer flow passage and unmatched fluid flow within the wall boundaries. This paper presents the effect of rounding the impeller leading edges of the pump on turbine performance. A CFD model of a PAT was designed to simulate virtual performance for the analysis. The aim of this study is to observe the internal hydraulic performance resulting from the changes in the performance characteristics. Highest efficiency was recorded at 17.0 l/s, an increase of 0.18%. The simulation results reveal that there is an improvement in hydraulic performance at overflow operation. The velocity vector visualization shows that there is a reduction in wake and consequently less flow separation along impeller flow passages. However, adjusting the sensitive impeller inlet geometry will also alter the velocity inlet vector and consequently change the velocity triangles for the turbo machinery system.

Mr. Pat McDonald, Director of "Key Business Technologies", Department of Trade and Industry, United Kingdom

CERN Multimedia

Maximilien Brice

2002-01-01

Photos 01,02: Mr Pat McDonald, Director of "Key Business Technologies", Department of Trade and Industry, UK (third from left, front) in front of the ATLAS End-Cap Toroid vacuum vessel in the ATLAS assembly hall with, from left to right, Fred Wickens, Chris Jones, Peter Fletcher, Ray Browne, Neil Geddes, Jim Fleming, Anne Trefethen, Jim Wilson, Edwin Towndrow, Sharon Bonfield, Guy Rickett, Ken Smith, Peter Jenni. Photo 03: Mr Pat McDonald, Director of "Key Business Technologies", Department of Trade and Industry, UK (fifth from left) visiting ATLAS assembly hall with, from left to right, Jim Wilson, Peter Jenni, Ken Smith, Edwin Towndrow, Ray Brown, Chris Jones, Neil Geddes, Sharon Bonfield, Anne Trefethen, Jim Fleming, Fred Wickens. Photo 04: Mr Pat McDonald, Director of "Key Business Technologies", Department of Trade and Industry, UK (fourth from right) in front of the ATLAS Barrel Toroid coil casing in the ATLAS assembly hall with, from left to right, Peter Jenni, Jim Wilson, Guy Rickett, Anne Trefethen, ...

School-to-Work Transition Services for Students with Disabilities in Malaysia: Organisations' Views on Policy and Practices

Science.gov (United States)

Abdullah, Melissa Ng Lee Yen; Mey, See Ching; Eng, Tan Kok; Othman, Rosly; Omar, Ahmad Fairuz

2013-01-01

Transition services are required by law for students with disabilities in many developed countries. In Malaysia, however, there is still no specific legislation mandating that school-to-work transition planning and services be provided to students with disabilities. This study investigated the state of the transition services provided by…

AISLAMIENTO Y CARACTERIZACIÓN MORFOLÓGICA DE Rosellinia pepo Pat. EN PLANTAS DE MACADAMIA ISOLATION AND MORPHOLOGICAL CHARACTERIZATION OF Rosellinia pepo Pat. IN MACADAMIA PLANTS

Directory of Open Access Journals (Sweden)

Carmen Eliana Realpe Ortiz

2006-12-01

Full Text Available El hongo Rosellinia pepo Pat., causante de la llaga estrellada, se considera uno de los principales problemas fitosanitarios de la macadamia por ocasionar la muerte de la planta en su etapa productiva. Debido a que no existe una metodología de aislamiento confiable que asegure la recuperación del hongo con un porcentaje mínimo de contaminación y los estudios relacionados con este patógeno son escasos se planteó una investigación con el fin de perfeccionar una metodología de aislamiento y realizar algunas caracterizaciones morfológicas de este patógeno. La nueva metodología permitió obtener aislamientos con un 91,26% de pureza del hongo. La tasa de crecimiento fue de 4,68 mm día-1. Las colonias son de color blanco y apariencia algodonosa en su inicio, pero a medida que envejece el micelio toma un color café o negro y su apariencia se torna quebradiza. La observación de micelio blanco en forma de estrella en el lado interior del medio sintético permite diferenciarlo de otras especies como R. bunodes. Las mediciones microscópicas de los hinchamientos piriformes presentaron en promedio 106,4mm de largo y 75,3mm de ancho. Este trabajo también permitió determinar el nivel de inóculo infectivo.The fungus Rosellinia pepo Pat, the causal agent of star gall, is considered to be a main phytosanitary problem to the Macademia tree by causing the death of the tree while in its productive stage. Because no reliable isolation method exists that assures recovery of the mushroom with a minimum percentage of contamination and studies of this pathogen are scarce. This study was conducted to perfect an isolation methodology and permit some morphological characterizations of this pathogen. The new methodology allowed isolations with 91,26% purity of mushroom to be obtained. The rate of growth was 4,68 mm day-1. The colonies were of white color and cottony appearance in the beginning, but as the micelio aged it assumed a brown or black color and a

Health care transition for adolescents with special health care needs: a report on the development and use of a clinical transition service.

Science.gov (United States)

McLaughlin, Suzanne; Bowering, Nancy; Crosby, Barbara; Neukirch, Jodie; Gollub, Eliza; Garneau, Deborah

2013-04-01

A growing population of adolescents with special healthcare needs is aging into adulthood. These emerging adults face the transition challenges of their healthy peers but also potentially heightened risks and challenges related to their conditions. We describe the process of developing a pilot program to support healthcare services for emerging adults with chronic conditions and present preliminary data on utilization. An outpatient multidisciplinary consult model was developed based on patient, family and physician feedback. Patients with diverse conditions were equally referred from primary care, subspecialists and families and community agencies. Services provided included needs assessments (100%), referral to adult physicians (77%), care coordination (52%) and referrals to adult community services (10%). Clinical billing did not fully support the cost of providing services. The pilot program offered multidisciplinary transition services that were utilized by a diverse patient population. Local and national resources for health care transition are provided.

Annex 2: performance audit tool PAT

Energy Technology Data Exchange (ETDEWEB)

Kaldorf, S.; Gruber, P.

2000-10-15

This annex to the report takes a look at experience gained with one of two expert systems used for error-detection and diagnosis in existing buildings. The Performance Audit Tool PAT is based on an expert system for the detection and diagnosis of under-performance. Its aim is to assist the system's operator. It was developed as a stand-alone system which periodically runs a remote detection and diagnosis check. The various types of under-performance that the system can detect are discussed. The first objective of this study was to present the structure of the tool and describe its application to two types of system: a central air-handling unit and individual zones. The second objective was to discuss experience gained with this type of tool.

El sistema ubicuitina/proteasoma en la interacción planta-patógeno

Directory of Open Access Journals (Sweden)

Mario Rocha-Sosa

2013-01-01

Full Text Available La ubicuitina (Ub es una proteína pequeña la cual es utilizada por los organismos eucariontes para marcar proteínas, en la mayoría de los casos para que éstas sean posteriormente degradadas. La ubicuitinación ocurre en tres pasos sucesivos los cuales requieren de la acción de una enzima activadora, una enzima conjugadora y una ligasa de Ub. Una vez ubicuitinada la proteína seguirá un destino diferente de acuerdo a la topología de la ubicuitinación. Muchas de las proteínas marcadas por ubicuitinación serán degradadas por un complejo proteínico de 2.5 Mda conocido como el proteasoma 26S. Las plantas emplean ampliamente este mecanismo de degradación regulada de proteínas para modular procesos de crecimiento y desarrollo o bien, para responder ante situaciones adversas como puede ser una baja disponibilidad de agua o el ataque por patógenos. Durante la evolución las plantas han desarrollado diversas estrategias para defenderse ante la agresión por patógenos, sin embargo, estos organismos han logrado implementar herramientas que les permiten contrarrestar los mecanismos de defensa de las plantas, entre otras formas, los patógenos han logrado manipular el sistema Ub/proteasoma para poder infectarlas eficientemente.

Older adults’ home- and community-based care service use and residential transitions: a longitudinal study

Directory of Open Access Journals (Sweden)

Chen Ya-Mei

2012-08-01

Full Text Available Abstract Background As Home-and Community-Based Services (HCBS, such as skilled nursing services or personal care services, have become increasingly available, it has become clear that older adults transit through different residential statuses over time. Older adults may transit through different residential statuses as the various services meet their needs. The purpose of this exploratory study was to better understand the interplay between community-dwelling older adults’ use of home- and community-based services and their residential transitions. Methods The study compared HCBS service-use patterns and residential transitions of 3,085 older adults from the Second Longitudinal Study of Aging. Based on older adults’ residential status at the three follow-up interviews, four residential transitions were tracked: (1 Community-Community-Community (CCC: Resided in community during the entire study period; (2 Community-Institution-Community (CIC: Resided in community at T1, had lived in an institution at some time between T1 and T2, then had returned to community by T3; (3 Community-Community-Institution (CCI: Resided in community between at T1, and betweenT1 and T2, including at T2, but had used institutional services between T2 and T3; (4 Community-Institution-Institution (CII: Resided in community at T1 but in an institution at some time between T1 and T2, and at some time between T2 and T3.. Results Older adults’ use of nondiscretionary and discretionary services differed significantly among the four groups, and the patterns of HCBS use among these groups were also different. Older adults’ use of nondiscretionary services, such as skilled nursing care, may help them to return to communities from institutions. Personal care services (PCS and senior center services may be the key to either support elders to stay in communities longer or help elders to return to their communities from institutions. Different combinations of PCS with other

Combining two open source tools for neural computation (BioPatRec and Netlab) improves movement classification for prosthetic control.

Science.gov (United States)

Prahm, Cosima; Eckstein, Korbinian; Ortiz-Catalan, Max; Dorffner, Georg; Kaniusas, Eugenijus; Aszmann, Oskar C

2016-08-31

Controlling a myoelectric prosthesis for upper limbs is increasingly challenging for the user as more electrodes and joints become available. Motion classification based on pattern recognition with a multi-electrode array allows multiple joints to be controlled simultaneously. Previous pattern recognition studies are difficult to compare, because individual research groups use their own data sets. To resolve this shortcoming and to facilitate comparisons, open access data sets were analysed using components of BioPatRec and Netlab pattern recognition models. Performances of the artificial neural networks, linear models, and training program components were compared. Evaluation took place within the BioPatRec environment, a Matlab-based open source platform that provides feature extraction, processing and motion classification algorithms for prosthetic control. The algorithms were applied to myoelectric signals for individual and simultaneous classification of movements, with the aim of finding the best performing algorithm and network model. Evaluation criteria included classification accuracy and training time. Results in both the linear and the artificial neural network models demonstrated that Netlab's implementation using scaled conjugate training algorithm reached significantly higher accuracies than BioPatRec. It is concluded that the best movement classification performance would be achieved through integrating Netlab training algorithms in the BioPatRec environment so that future prosthesis training can be shortened and control made more reliable. Netlab was therefore included into the newest release of BioPatRec (v4.0).

Impacto do Programa Água para Todos (PAT sobre a morbi-mortalidade por diarreia em crianças do Estado da Bahia, Brasil Impacto del Programa Agua para Todos (PAT sobre la morbimortalidad por diarrea en niños del Estado de Bahía, Brasil Impact of the Water for All Program (PAT on childhood morbidity and mortality from diarrhea in the Bahia State, Brazil

Directory of Open Access Journals (Sweden)

Davide Rasella

2013-01-01

Full Text Available O objetivo do presente estudo foi avaliar o impacto do Programa Água para Todos (PAT, implantado no Estado da Bahia, Brasil, por ampliar a cobertura do saneamento básico em áreas de maior vulnerabilidade. Foram selecionados 224 municípios com informações vitais adequadas. Foi utilizado um desenho de estudo antes-e-depois controlado, efetuando uma análise de regressão multivariada para dados em painel com resposta binomial negativa a efeitos fixos do ano 2005 até 2008. A cobertura do PAT, como variável contínua, esteve associada negativamente (p El objetivo del presente estudio fue evaluar el impacto del Programa Agua para Todos (PAT, implantado en el Estado de Bahía, Brasil, para ampliar la cobertura del saneamiento básico en áreas de mayor vulnerabilidad. Fueron seleccionados 224 municipios con información vital adecuada. Se utilizó un diseño de estudio antes-después controlado, efectuando un análisis de regresión multivariada para los datos en panel con respuesta binomial negativa, a efectos fijos del año 2005 hasta el 2008. La cobertura del PAT, como variable continua, estuvo asociada negativamente (p This study aimed to evaluate the impact of the Water for All Program (PAT, launched in Bahia State, Brazil, with the objective of expanding coverage of the water supply and sanitation in areas with high vulnerability to waterborne diseases. A total of 224 municipalities (counties with adequate vital statistics were selected. A controlled before-and-after study design was used, performing analyses with multivariate negative binomial regression with fixed effects, from 2005 to 2008. PAT coverage - as a continuous variable - was negatively associated (p < 0.01 with the under-five mortality rate. Municipalities with coverage ≥ 10% showed a reduction of 39% (p < 0.05 in mortality from diarrhea, under-five mortality of 14% (p < 0.01, and hospitalizations from diarrhea of 6% (p < 0.05 when compared to municipalities without PAT

Inline monitoring and a PAT strategy for pharmaceutical hot melt extrusion.

Science.gov (United States)

Wahl, Patrick R; Treffer, Daniel; Mohr, Stefan; Roblegg, Eva; Koscher, Gerold; Khinast, Johannes G

2013-10-15

Implementation of continuous manufacturing in the pharmaceutical industry requires tight process control. This study focuses on a PAT strategy for hot melt extrusion of vegetable calcium stearate (CaSt) as matrix carrier and paracetamol as active pharmaceutical ingredient (API). The extrusion was monitored using in-line near-infrared (NIR) spectroscopy. A NIR probe was located in the section between the extrusion screws and the die, using a novel design of the die channel. A chemometric model was developed based on premixes at defined concentrations and was implemented in SIPAT for real time API concentration monitoring. Subsequently, step experiments were performed for different API concentrations, screw speeds and screw designs. The predicted API concentration was in good agreement with the pre-set concentrations. The transition from one API plateau to another was a smooth curve due to the mixing behaviour of the extruder. The accuracy of the model was confirmed via offline HPLC analysis. The screw design was determined as the main influential factor on content uniformity (CU). Additionally the influence of multiple feeders had a significant impact on CU. The results demonstrate that in-line NIR measurements is a powerful tool for process development (e.g., mixing characterization), monitoring and further control strategies. Copyright © 2013. Published by Elsevier B.V.

X-PAT: a multiplatform patient referral data management system for small healthcare institution requirements.

Science.gov (United States)

Masseroli, Marco; Marchente, Mario

2008-07-01

We present X-PAT, a platform-independent software prototype that is able to manage patient referral multimedia data in an intranet network scenario according to the specific control procedures of a healthcare institution. It is a self-developed storage framework based on a file system, implemented in eXtensible Markup Language (XML) and PHP Hypertext Preprocessor Language, and addressed to the requirements of limited-dimension healthcare entities (small hospitals, private medical centers, outpatient clinics, and laboratories). In X-PAT, healthcare data descriptions, stored in a novel Referral Base Management System (RBMS) according to Health Level 7 Clinical Document Architecture Release 2 (CDA R2) standard, can be easily applied to the specific data and organizational procedures of a particular healthcare working environment thanks also to the use of standard clinical terminology. Managed data, centralized on a server, are structured in the RBMS schema using a flexible patient record and CDA healthcare referral document structures based on XML technology. A novel search engine allows defining and performing queries on stored data, whose rapid execution is ensured by expandable RBMS indexing structures. Healthcare personnel can interface the X-PAT system, according to applied state-of-the-art privacy and security measures, through friendly and intuitive Web pages that facilitate user acceptance.

A Service Member's Self in Transition : A Longitudinal Case Study Analysis

NARCIS (Netherlands)

Grimell, Jan

2017-01-01

Adopting a narrative approach with a dialogical framework, a longitudinal case study is presented that describes a service member's self in transition from active service into the civilian population. An analysis and interpretation of the case study leads to the hypothesis that if a dominant

Transitions of Care from Child and Adolescent Mental Health Services to Adult Mental Health Services (TRACK Study: A study of protocols in Greater London

Directory of Open Access Journals (Sweden)

Ford Tamsin

2008-06-01

Full Text Available Abstract Background Although young people's transition from Child and Adolescent Mental Health Services (CAMHS to Adult Mental Health Services (AMHS in England is a significant health issue for service users, commissioners and providers, there is little evidence available to guide service development. The TRACK study aims to identify factors which facilitate or impede effective transition from CAHMS to AMHS. This paper presents findings from a survey of transition protocols in Greater London. Methods A questionnaire survey (Jan-April 2005 of Greater London CAMHS to identify transition protocols and collect data on team size, structure, transition protocols, population served and referral rates to AMHS. Identified transition protocols were subjected to content analysis. Results Forty two of the 65 teams contacted (65% responded to the survey. Teams varied in type (generic/targeted/in-patient, catchment area (locality-based, wider or national and transition boundaries with AMHS. Estimated annual average number of cases considered suitable for transfer to AMHS, per CAMHS team (mean 12.3, range 0–70, SD 14.5, n = 37 was greater than the annual average number of cases actually accepted by AMHS (mean 8.3, range 0–50, SD 9.5, n = 33. In April 2005, there were 13 active and 2 draft protocols in Greater London. Protocols were largely similar in stated aims and policies, but differed in key procedural details, such as joint working between CAHMS and AMHS and whether protocols were shared at Trust or locality level. While the centrality of service users' involvement in the transition process was identified, no protocol specified how users should be prepared for transition. A major omission from protocols was procedures to ensure continuity of care for patients not accepted by AMHS. Conclusion At least 13 transition protocols were in operation in Greater London in April 2005. Not all protocols meet all requirements set by government policy. Variation in

The slow search for solutions: Lessons from historical energy transitions by sector and service

International Nuclear Information System (INIS)

Fouquet, Roger

2010-01-01

This paper reviews past energy transitions by sector and service to identify features that may be useful for future transitions. Although often considered a single event, the transition from traditional energy sources to fossil fuels involved numerous services and sectors at different times between 1500 and 1920. The main economic drivers identified for energy transitions were the opportunities to produce cheaper or better energy services. The existence of a niche market willing to pay more for these characteristics enabled new energy sources and technologies to be refined gradually until they could compete with the incumbent energy source. Nevertheless, this implied that, on average, the whole innovation chain took more than 100 years and the diffusion phase nearly 50 years. In the same way, low-carbon energy sources and technologies offer an additional characteristic (i.e. low carbon impact), which might be able to develop gradually in a niche market until they can compete with fossil fuels. However, because of consumers' tendency to free-ride, a successful transition will need governments to provide protection of this niche market-possibly for decades. Based on past experiences, a complete transition to a low carbon economy is likely to be very slow.

77 FR 5252 - Federal Travel Regulation; GSA E-Gov Travel Service (ETS) Transition to E-Gov Travel Service 2...

Science.gov (United States)

2012-02-02

... Travel Regulation; GSA E-Gov Travel Service (ETS) Transition to E-Gov Travel Service 2 (ETS2) AGENCY..., ETS Program Manager Center for Travel Management (QMCD), Office of Travel and Transportation Services (QMC), at [email protected] or (703) 605-2151. SUPPLEMENTARY INFORMATION: The Federal Travel...

Dispatching demand response transit service maximizing productivity and service quality guidebook : final report, March 2009.

Science.gov (United States)

2009-03-01

The ability of transit agencies to staff dispatch effectively and use technology to its full advantage is critical : in responding proactively as service changes occur and in making sound routing decisions. Sound routing : decisions result in improve...

Dual RNA Processing Roles of Pat1b via Cytoplasmic Lsm1-7 and Nuclear Lsm2-8 Complexes

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Caroline Vindry

2017-08-01

Full Text Available Pat1 RNA-binding proteins, enriched in processing bodies (P bodies, are key players in cytoplasmic 5′ to 3′ mRNA decay, activating decapping of mRNA in complex with the Lsm1-7 heptamer. Using co-immunoprecipitation and immunofluorescence approaches coupled with RNAi, we provide evidence for a nuclear complex of Pat1b with the Lsm2-8 heptamer, which binds to the spliceosomal U6 small nuclear RNA (snRNA. Furthermore, we establish the set of interactions connecting Pat1b/Lsm2-8/U6 snRNA/SART3 and additional U4/U6.U5 tri-small nuclear ribonucleoprotein particle (tri-snRNP components in Cajal bodies, the site of snRNP biogenesis. RNA sequencing following Pat1b depletion revealed the preferential upregulation of mRNAs normally found in P bodies and enriched in 3′ UTR AU-rich elements. Changes in >180 alternative splicing events were also observed, characterized by skipping of regulated exons with weak donor sites. Our data demonstrate the dual role of a decapping enhancer in pre-mRNA processing as well as in mRNA decay via distinct nuclear and cytoplasmic Lsm complexes.

An Assessment of Future Demands for and Benefits of Public Transit Services in Tennessee

Energy Technology Data Exchange (ETDEWEB)

Southworth, F.

2003-06-10

This report documents results from a study carried out by Oak Ridge National Laboratory and the University of Tennessee at Knoxville for the Office of Public Transportation, Tennessee Department of Transportation. The study team was tasked with developing a process and a supporting methodology for estimating the benefits accruing to the State from the operation of state supported public transit services. The team was also tasked with developing forecasts of the future demands for these State supported transit services at five year intervals through the year 2020, broken down where possible to the local transit system level. Separate ridership benefits and forecasts were also requested for the State's urban and rural transit operations. Tennessee's public transit systems are subsidized to a degree by taxpayers. It is therefore in the public interest that assessments of the benefits of such systems be carried out at intervals, to determine how they are contributing to the well-being of the state's population. For some population groups within the State of Tennessee these transit services have become essential as a means of gaining access to workplaces and job training centers, to educational and health care facilities, as well as to shops, social functions and recreational sites.

Dāvināšana kā patērēšanas kultūras iezīme. Parfimērijas iegādes ietekmējošie faktori

OpenAIRE

Liepiņa, Krista

2016-01-01

Bakalaura darba “Dāvināšana kā patērēšanas kultūras iezīme. Parfimērijas iegādes ietekmējošie faktori” mērķis ir izpētīt, kas ir patērēšana un kas ietekmē patērētāju uzvedību ikdienā, kā arī svētku laikā, lēmuma pieņemšanas procesā, izvēloties preces dāvināšanas mērķim, nevis personīgai lietošanai. Darba teorētiskajā daļā apskatītas tādu jēdzienu teorētiskie aspekti kā patērēšana un patērniecība, patērēšanas kultūra, patērētāju uzvedība, patērētāju identitāte, kā arī tiek apskatīta dāvanu dāv...

Transition to School from Pacific Islands Early Childhood Services.

Science.gov (United States)

Sauvao, Le'autuli'ilagi M.; Mapa, Lia; Podmore, Valerie N.

Noting the need for additional information on the transition of children from Pacific Islands early childhood services to primary school, this exploratory study was designed to provide an account of the experiences of children, parents, and teachers, focusing on language and other aspects of children's move from Pacific Islands early childhood…

Protocol for a cohort study of adolescent mental health service users with a nested cluster randomised controlled trial to assess the clinical and cost-effectiveness of managed transition in improving transitions from child to adult mental health services (the MILESTONE study)

NARCIS (Netherlands)

Singh, S.P. (Swaran P.); Tuomainen, H. (Helena); Girolamo, G.D. (Giovanni De); A. Maras (Athanasios); P. Santosh (Paramala); McNicholas, F. (Fiona); Schulze, U. (Ulrike); Purper-Ouakil, D. (Diane); Tremmery, S. (Sabine); Franić, T. (Tomislav); Madan, J. (Jason); Paul, M. (Moli); F.C. Verhulst (Frank); G.C. Dieleman (Gwen); Warwick, J. (Jane); Wolke, D. (Dieter); Street, C. (Cathy); Daffern, C. (Claire); Tah, P. (Priya); Griffin, J. (James); Canaway, A. (Alastair); Signorini, G. (Giulia); Gerritsen, S. (Suzanne); Adams, L. (Laura); O'Hara, L. (Lesley); Aslan, S. (Sonja); Russet, F. (Frédérick); Davidović, N. (Nikolina); Tuffrey, A. (Amanda); Wilson, A. (Anna); Gatherer, C. (Charlotte); Walker, L. (Leanne)

2017-01-01

textabstractIntroduction Disruption of care during transition from child and adolescent mental health services (CAMHS) to adult mental health services may adversely affect the health and well-being of service users. The MILESTONE (Managing the Link and Strengthening Transition from Child to Adult

Teacher's PAT? Multiple-Role Principal-Agent Theory, Education Politics, and Bureaucrat Power

Science.gov (United States)

Vanhuysse, Pieter; Sulitzeanu-Kenan, Raanan

2009-01-01

This article aims to contribute to current debates about political power and agency relationships in education and other public sectors. In a recent clarion call for a major redirection of political principal-agent theories (PAT), Terry Moe has argued that standard information asymmetries ought no longer to be regarded as the sole foundation of…

Unintended greenhouse gas consequences of lowering level of service in urban transit systems

International Nuclear Information System (INIS)

Griswold, Julia B; Cheng, Han; Madanat, Samer; Horvath, Arpad

2014-01-01

Public transit is often touted as a ‘green’ transportation option and a way for users to reduce their environmental footprint by avoiding automobile emissions, but that may not be the case when systems run well below passenger capacity. In previous work, we explored an approach to optimizing the design and operations of transit systems for both costs and emissions, using continuum approximation models and assuming fixed demand. In this letter, we expand upon our previous work to explore how the level of service for users impacts emissions. We incorporate travel time elasticities into the optimization to account for demand shifts from transit to cars, resulting from increases in transit travel time. We find that emissions reductions are moderated, but not eliminated, for relatively inelastic users. We consider two scenarios: the first is where only the agency faces an emissions budget; the second is where the entire city faces an emissions budget. In the latter scenario, the emissions reductions resulting from reductions in transit level of service are mitigated as users switch to automobile. (letter)

Mark report satellite tags (mrPATs) to detail large-scale horizontal movements of deep water species: First results for the Greenland shark (Somniosus microcephalus)

Science.gov (United States)

Hussey, Nigel E.; Orr, Jack; Fisk, Aaron T.; Hedges, Kevin J.; Ferguson, Steven H.; Barkley, Amanda N.

2018-04-01

The deep-sea is increasingly viewed as a lucrative environment for the growth of resource extraction industries. To date, our ability to study deep-sea species lags behind that of those inhabiting the photic zone limiting scientific data available for management. In particular, knowledge of horizontal movements is restricted to two locations; capture and recapture, with no temporal information on absolute animal locations between endpoints. To elucidate the horizontal movements of a large deep-sea fish, a novel tagging approach was adopted using the smallest available prototype satellite tag - the mark-report pop-up archival tag (mrPAT). Five Greenland sharks (Somniosus microcephalus) were equipped with multiple mrPATs as well as a standard archival satellite tag (miniPAT) that were programmed to release in sequence at 8-10 day intervals. The performance of the mrPATs was quantified. The tagging approach provided multiple locations per individual and revealed a previously unknown directed migration of Greenland sharks from the Canadian high Arctic to Northwest Greenland. All tags reported locations, however, the accuracy and time from expected release were variable among tags (average time to an accurate location from expected release = 30.8 h, range: 4.9-227.6 h). Average mrPAT drift rate estimated from best quality messages (LQ1,2,3) was 0.37 ± 0.09 m/s indicating tags were on average 41.1 ± 63.4 km (range: 6.5-303.1 km) from the location of the animal when they transmitted. mrPATs provided daily temperature values that were highly correlated among tags and with the miniPAT (70.8% of tag pairs were significant). In contrast, daily tilt sensor data were variable among tags on the same animal (12.5% of tag pairs were significant). Tracking large-scale movements of deep-sea fish has historically been limited by the remote environment they inhabit. The current study provides a new approach to document reliable coarse scale horizontal movements to understand

The role of service design practices in enabling and embedding the servitization transition

NARCIS (Netherlands)

Calabretta, G.; de Lille, C.S.H.; Beck, Caroline; Bohemia, E.; de Bont, C.; Svengren Holm, L.

2017-01-01

An increasing number of companies are embracing the transition from a product focus to a service focus in their offering in order to face the challenges of the experience economy. However such transition (i.e., servitization) is challenging, since it requires companies to change both their processes

Eliminación de patógenos en biosólidos por estabilización alcalina

Directory of Open Access Journals (Sweden)

Silva Leal Jorge Antonio

2009-09-01

Full Text Available La Planta de Tratamiento de Aguas Residuales de Cañaveralejo –PTAR-C de Cali– Colombia, produce alrededor de 100 t/día de biosólidos que, aunque no tienen restricción por metales pesados, son clase B por el nivel de microorganismos patógenos y parásitos. En un diseño completamente al azar, conformado por seis tratamientos con su respectivo duplicado, se evaluó la estabilización alcalina con dosis del 9% peso a peso de cal viva e hidratada, aplicada a pilas de 0.5 t de biosólidos húmedos (66.5% y secos a temperatura ambiente (25 - 31°C durante 72 h (humedad 50.1%. Con la estabilización alcalina el pH aumentó a valores superiores a 12 unidades durante el tiempo suficiente para garantizar la reducción de patógenos y parásitos, alcanzando un material clase A; sin embargo, el biosólido seco facilitó la formación de grumos que dificultaron las labores de homogenización del sustrato con los alcalinizantes, factor indeseable para la eficiente reducción de patógenos.

Eliminación de patógenos en biosólidos por estabilización alcalina

Directory of Open Access Journals (Sweden)

Patricia Torres Lozada

2009-07-01

Full Text Available La Planta de Tratamiento de Aguas Residuales de Cañaveralejo -PTAR-C de Cali- Colombia, produce alrededor de 100 t/día de biosólidos que, aunque no tienen restricción por metales pesados, son clase B por el nivel de microorganismos patógenos y parásitos. En un diseño completamente al azar, conformado por seis tratamientos con su respectivo duplicado, se evaluó la estabilización alcalina con dosis del 9% peso a peso de cal viva e hidratada, aplicada a pilas de 0.5 t de biosólidos húmedos (66.5% y secos a temperatura ambiente (25 - 31°C durante 72 h (humedad 50.1%. Con la estabilización alcalina el pH aumentó a valores superiores a 12 unidades durante el tiempo suficiente para garantizar la reducción de patógenos y parásitos, alcanzando un material clase A; sin embargo, el biosólido seco facilitó la formación de grumos que dificultaron las labores de homogenización del sustrato con los alcalinizantes, factor indeseable para la eficiente reducción de patógenos.

Examination of Regional Transit Service Under Contracting : A Case Study in the Greater New Orleans Region

Science.gov (United States)

2011-04-01

Many local governments and transit agencies in the United States face financial difficulties in providing adequate public transit service in individual systems, and in providing sufficient regional coordination to accommodate transit trips involving ...

Safety evaluation of the phosphinothricin acetyltransferase proteins encoded by the pat and bar sequences that confer tolerance to glufosinate-ammonium herbicide in transgenic plants.

Science.gov (United States)

Hérouet, Corinne; Esdaile, David J; Mallyon, Bryan A; Debruyne, Eric; Schulz, Arno; Currier, Thomas; Hendrickx, Koen; van der Klis, Robert-Jan; Rouan, Dominique

2005-03-01

Transgenic plant varieties, which are tolerant to glufosinate-ammonium, were developed. The herbicide tolerance is based upon the presence of either the bar or the pat gene, which encode for two homologous phosphinothricin acetyltransferases (PAT), in the plant genome. Based on both a review of published literature and experimental studies, the safety assessment reviews the first step of a two-step-approach for the evaluation of the safety of the proteins expressed in plants. It can be used to support the safety of food or feed products derived from any crop that contains and expresses these PAT proteins. The safety evaluation supports the conclusion that the genes and the donor microorganisms (Streptomyces) are innocuous. The PAT enzymes are highly specific and do not possess the characteristics associated with food toxins or allergens, i.e., they have no sequence homology with any known allergens or toxins, they have no N-glycosylation sites, they are rapidly degraded in gastric and intestinal fluids, and they are devoid of adverse effects in mice after intravenous administration at a high dose level. In conclusion, there is a reasonable certainty of no harm resulting from the inclusion of the PAT proteins in human food or in animal feed.

Utilisation and Satisfaction with Rehabilitation Services in Children with Primary Language Impairment Transitioning to School: Parents' Perspective

Science.gov (United States)

Mazer, Barbara; Dion, Karyne; Moryoussef, Aguy

2017-01-01

Children with disabilities require coordinated services to optimise transition into school. This study compared type, frequency and approach to service utilisation for children with primary language impairment transitioning from rehabilitation to the educational system, and examined parent satisfaction. Parents responded to a telephone…

Microorganismos patógenos y potencialmente patógenos en secreciones genitales de gestantes a término asociados a complicaciones posnatales

Directory of Open Access Journals (Sweden)

Tania Castellanos Medina

2013-09-01

Full Text Available Introducción: tanto las infecciones puerperales como las neonatales precoces reflejan probablemente los microorganismos que están presentes en la vagina en el período cercano al parto. Objetivo: establecer la relación entre los microorganismos identificados en las secreciones genitales de las gestantes a término y el desarrollo de sepsis neonatal y puerperal, así como vincular dichas complicaciones con los agentes diagnosticados. Métodos: se realizó un estudio longitudinal y prospectivo en los servicios de microbiología, obstetricia, perinatología y neonatología del Hospital General Docente "Dr. "Juan Bruno Zayas Alfonso", de Santiago de Cuba, desde julio de 2009 hasta marzo de 2010. Se identificaron microorganismos en 179 muestras cervicovaginales, las cuales fueron procesadas en el laboratorio de microbiología según las normas vigentes. Resultados: los microorganismos más identificados resultaron los géneros Mycoplasmas y Chlamydias (78,2 y 69,3%, respectivamente y fueron los que con mayor frecuencia se asociaron. Un porcentaje elevado de las gestantes (67,0 %, tenía más de un agente en sus secreciones genitales. Después del parto hubo un hallazgo mayor de infecciones en el producto de la concepción (21,8 % que en las puérperas (3,9% y la mayoría de estas complicaciones se relacionaron con la presencia de 2 o más microorganismos. Conclusiones: las asociaciones de microorganismos patógenos o potencialmente patógenos en las secreciones genitales de embarazadas a término, aumentan el riesgo de complicaciones posnatales.

Pump Application as Hydraulic Turbine – Pump as Turbine (PaT)

OpenAIRE

Rusovs, D

2009-01-01

The paper considers pump operation as hydraulic turbine with purpose to produce mechanical power from liquid flow. The Francis hydraulic turbine was selected for comparison with centrifugal pump in reverse operation. Turbine and centrifugal pump velocity triangles were considered with purpose to evaluate PaT efficiency. Shape of impeller blades for turbine and pumps was analysed. Specific speed calculation is carried out with purpose to obtain similarity in pump and turbine description. For ...

Martin Luther King, Jr. East Busway in Pittsburgh, PA

Science.gov (United States)

1987-10-01

The Port Authority of Allegheny County (PAT), the primary public transit operator in Pittsburgh, PA, built an exclusive roadway for buses which opened for service in February 1983. The two-lane, 6.8-mile facility serves the eastern suburbs via a righ...

Sociālo tīklu un platformas "Facebook" ietekme uz patērētāja pirkuma lēmuma pieņemšanas procesu.

OpenAIRE

Ķiksis, Kristiāns

2017-01-01

Bakalaura darba tēma ir “Sociālo tīklu un platformas “Facebook” ietekme uz patērētāja pirkuma lēmuma pieņemšanas procesu”. Veiktā darba mērķis ir izskaidrot, kāpēc, kad un kā sociālie mediji ir ietekmējuši patērētāju lēmumu pieņemšanas procesu. Teorētiskā daļa sastāv no 4 sadaļām- patērētāju uzvedība, sociālie mediji, sociālo mediju ietekme uz patērētājiem, kā arī platformas “Facebook” iespējas. Darbs ietver 4 nodaļas. Bakalaura darba teorētiskajā daļā apkopoti materiāli par patērētāju uzvedī...

Longitudinal Evaluation of Transition Services (“LETS Study”: Protocol for outcome evaluation

Directory of Open Access Journals (Sweden)

Tsybina Irina

2012-05-01

Full Text Available Abstract Background Because of advances in medical treatment, most children with physical disabilities can expect to achieve near normal life spans. Typically, coordinated teams of health care providers in specialized pediatric settings care for these children. As these children reach adulthood, however, the availability of services and expertise changes because the adult health care system has different processes designed to meet their specialized needs. Gaps in continuity of care during the transition from pediatric to adult services, and associated poor health outcomes are well documented. In response, new models of care are being introduced to address the complex process of health care transition. This paper describes a study protocol of a client-centred, prospective, longitudinal, mixed-method evaluation of linked model of health care across the lifespan (the LIFEspan Model, offered by a pediatric rehabilitation centre and an adult rehabilitation centre. Method This project will include a process and an outcome evaluation of the LIFEspan Model. The process evaluation will detail the specific service delivery that occurs with respect to preparation for transition and transfer of care through chart audits of pediatric medical records and qualitative interviews with LIFEspan staff. The outcome evaluation will measure the effect of the model on: 1 maintaining continuity within the health care system from pediatric to adult care; and 2 secondary outcomes related to health, well-being, social participation, transition readiness, and health care utilization of youth with cerebral palsy and acquired brain injury. Standardized instruments will include Health Utilities Inventory, Assessment of Life Habits, Arc’s Self-Determination, Assessment of Health-Related Quality of Life, Partners in Health Questionnaire, Social Support Questionnaire, and Self-Efficacy for Managing Chronic Disease. Discussion The LETS study will be original in its undertaking

Development of Process Analytical Technology (PAT) methods for controlled release pellet coating.

Science.gov (United States)

Avalle, P; Pollitt, M J; Bradley, K; Cooper, B; Pearce, G; Djemai, A; Fitzpatrick, S

2014-07-01

This work focused on the control of the manufacturing process for a controlled release (CR) pellet product, within a Quality by Design (QbD) framework. The manufacturing process was Wurster coating: firstly layering active pharmaceutical ingredient (API) onto sugar pellet cores and secondly a controlled release (CR) coating. For each of these two steps, development of a Process Analytical Technology (PAT) method is discussed and also a novel application of automated microscopy as the reference method. Ultimately, PAT methods should link to product performance and the two key Critical Quality Attributes (CQAs) for this CR product are assay and release rate, linked to the API and CR coating steps respectively. In this work, the link between near infra-red (NIR) spectra and those attributes was explored by chemometrics over the course of the coating process in a pilot scale industrial environment. Correlations were built between the NIR spectra and coating weight (for API amount), CR coating thickness and dissolution performance. These correlations allow the coating process to be monitored at-line and so better control of the product performance in line with QbD requirements. Copyright © 2014 Elsevier B.V. All rights reserved.

Unpacking Pat Parker: Intersections and Revolutions in "Movement in Black".

Science.gov (United States)

Washburn, Amy

2015-01-01

This article explores Pat Parker's poem "Movement in Black." It examines the ways in which she emblematizes intersectionality and simultaneity as forms of revolution in struggles of self and society. It begins with a theoretical and historical apparatus to contextualize Parker as an artist and activist. Then it offers a literary analysis of the poem, focusing on themes of time and space, marginalization and movement, difference and power, visibility and invisibility, and history and memory. It argues that Parker uses autobiographical writing to fuse personal and political sites of resistance.

Inline UV/Vis spectroscopy as PAT tool for hot-melt extrusion.

Science.gov (United States)

Wesholowski, Jens; Prill, Sebastian; Berghaus, Andreas; Thommes, Markus

2018-01-11

Hot-melt extrusion on co-rotating twin screw extruders is a focused technology for the production of pharmaceuticals in the context of Quality by Design. Since it is a continuous process, the potential for minimizing product quality fluctuation is enhanced. A typical application of hot-melt extrusion is the production of solid dispersions, where an active pharmaceutical ingredient (API) is distributed within a polymer matrix carrier. For this dosage form, the product quality is related amongst others to the drug content. This can be monitored on- or inline as critical quality attribute by a process analytical technology (PAT) in order to meet the specific requirements of Quality by Design. In this study, an inline UV/Vis spectrometer from ColVisTec was implemented in an early development twin screw extruder and the performance tested in accordance to the ICH Q2 guideline. Therefore, two API (carbamazepine and theophylline) and one polymer matrix (copovidone) were considered with the main focus on the quantification of the drug load. The obtained results revealed the suitability of the implemented PAT tool to quantify the drug load in a typical range for pharmaceutical applications. The effort for data evaluation was minimal due to univariate data analysis, and in combination with a measurement frequency of 1 Hz, the system is sufficient for real-time data acquisition.

Investigating Trauma in Narrating World War I: A Psychoanalytical Reading of Pat Barker's "Regeneration"

Science.gov (United States)

Sadjadi, Bakhtiar; Esmkhani, Farnaz

2016-01-01

The present paper seeks to critically read Pat Barker's "Regeneration" in terms of Cathy Caruth's psychoanalytic study of trauma. This analysis attempts to trace the concepts of latency, post-traumatic stress disorders, traumatic memory, and trauma in Barker's novel in order to explore how trauma and history are interrelated in the…

Systematic management of sealed source and nucleonic counting system in field service

International Nuclear Information System (INIS)

Mahadi Mustapha; Mohd Fitri Abdul Rahman; Jaafar Abdullah

2005-01-01

PAT group have received a lot of service from the oil and gas plant. All the services use sealed source and nucleonic counting system. This paper described the detail of management before going to the field service. This management is important to make sure the job is smoothly done and safe to the radiation worker and public. Furthermore this management in line with the regulation from LPTA. (Author)

Parents in transition: Experiences of parents of young people with a liver transplant transferring to adult services.

Science.gov (United States)

Wright, J; Elwell, L; McDonagh, J E; Kelly, D A; Wray, J

2017-02-01

Predictors of successful transition from pediatric to adult services include ability to self-manage and engage with healthcare services. Parents have a key role in healthcare management throughout childhood and adolescence including encouraging development of self-management skills in their children. Transition to adult services can be challenging for parents and young people, yet parents' views regarding transition remain largely unexplored. Nine parents of pediatric liver transplant recipients (15.2-25.1 yr) participated in semistructured interviews. Interviews were analyzed using IPA. Analysis revealed three key themes: "emotional impact of transplantation," "protection vs. independence," and "ending relationships and changing roles." Parents expressed the dichotomous nature of the desire to promote independence in their child while still maintaining control and protection, and discussed how changing roles and relationships were difficult to navigate. Parents are important facilitators of young people's development of self-management skills for successful transfer to adult services. Parents should be supported to move from a "managerial" to a "supervisory" role during transition to help young people engage independently with the healthcare team. Findings support the development of interventions for parents to emphasize their role in transition and guide the transfer of self-management skills from parent to young person. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Genética de la resistencia de la papa (Solanum tuberosum a patógenos. Estado de arte

Directory of Open Access Journals (Sweden)

Mosquera Teresa

2008-04-01

Full Text Available

Este artículo presenta una revisión de la resistencia en papa a patógenos, en cuanto a genes mapeados y clonados, y loci de rasgos cuantitativos (QTL mapeados, en la que se resaltan las relaciones entre resistencia cuantitativa y cualitativa en el caso P. infestans. El conocimiento logrado ha permitido generar un mapa funcional sobre el cual se localizan QTL para resistencia a patógenos. Se han mapeado 20 genes R de resistencia a virus, hongos, nematodos y oomicetos, utilizando marcadores moleculares. La mayoría de estos genes R fueron introducidos de especies silvestres. Catorce de ellos se encuentran en hot spots para resistencia y confieren resistencia a varios patógenos. A la fecha se han identificado cinco clusters de resistencia. La resistencia monogénica envuelve dos procesos básicos: percepción del ataque del patógeno, seguida de una respuesta para limitar la enfermedad. La percepción implica receptores específicos para cepas patogénicas, que son decodificadas por genes de resistencia. En una planta se encuentra un gran repertorio de genes de resistencia R, ubicados en diferentes sitios del genoma. Estos genes expresan diferentes proteínas que pueden ser agrupadas en varias familias. La mayoría de proteínas R contienen repeticiones en grupos, ricas en leucina (LRR. Se plantea la colocalización de genes R y QTL en diferentes cromosomas. Una hipótesis señala que los QTL son variantes alélicas con efecto menos extremo que los genes R y una segunda hipótesis plantea que los QTL de resistencia mapean en regiones del genoma que contienen genes de función conocida involucrados en la respuesta general al ataque de patógenos.

The Effects of Parent Training on Knowledge of Transition Services for Students with Disabilities

Science.gov (United States)

Young, John; Morgan, Robert L.; Callow-Heusser, Catherine A.; Lindstrom, Lauren

2016-01-01

This study examined effects of two parent-training approaches to increase knowledge of transition resources by (a) giving parents a brochure describing local transition services or (b) providing the same brochure plus 60 min of small-group training. We randomly assigned parents to groups who completed pre- and posttests on knowledge of transition…

Process synthesis for natural products from plants based on PAT methodology

DEFF Research Database (Denmark)

Malwade, Chandrakant Ramkrishna; Qu, Haiyan; Rong, Ben-Guang

2017-01-01

(QbD) approach, has been included at various steps to obtain molecular level information of process streams and thereby, support the rational decision making. The formulated methodology has been used to isolate and purify artemisinin, an antimalarial drug, from dried leaves of the plant Artemisia...... generates different process flowsheet alternatives consisting of multiple separation techniques. Decision making is supported by heuristics as well as basic process information already available from previous studies. In addition, process analytical technology (PAT) framework, a part of Quality by Design...

Perancangan Tata Kelola Layanan Teknologi Informasi Menggunakan ITIL versi 3 Domain Service Transition Dan Service Operation Di Pemerintah Kota Bandung

Directory of Open Access Journals (Sweden)

Luki Aisha Kusuma Wardani

2016-10-01

Full Text Available Nowadays, Information Technology plays an important role in an organization, and not only as a support equipment. Bandung City Government, as a government agency, make IT into one of the visions that need to be achieved. To achieve good governance based on Minister Regulation Number 41 in 2007, IT Governance is needed to ensure that the investment of IT can add value and align with institution’s objective. Bandung City Government currently doesn’t have policies and procedure that regulate about IT Service Management. Therefore, this study was conducted with the aim to create a guidance for Office of Communications and Information Technology of Bandung (Diskominfo to optimize the service provided. This study also aims to make Service Management governance so that the management of IT service have certain quality and meet the needs of business customers, and improve the quality as the agreement with the customers. This study was conducted using ITIL v3 with Service Operation and Service Transition domain. ITIL is IT Service Management best practice to improve the efficiency of IT operational. ISO 15504 was conducted to asses Capability Level of ITIL Process. Capability Level of Service Transition is 24.5% and Capability Level of Service Operation is 23%. Because of the inadequacy of the primary data, the assessment was also carried out by mapping the objective of institution with the risks related to the lack of ITIL processes. The results of the design are the governance policies and procedures related to the ITIL processes needed by the institution.

47 CFR 101.85 - Transition of the 18.3-19.3 GHz band from the terrestrial fixed services to the fixed-satellite...

Science.gov (United States)

2010-10-01

... terrestrial fixed services to the fixed-satellite service (FSS). 101.85 Section 101.85 Telecommunication... Transition of the 18.3-19.3 GHz band from the terrestrial fixed services to the fixed-satellite service (FSS...-satellite service (FSS). The rules in this section provide for a transition period during which FSS...

Review of the High Performance Antiproton Trap (HiPAT) Experiment at the Marshall Space Flight Center

Science.gov (United States)

Pearson, J. B.; Sims, Herb; Martin, James; Chakrabarti, Suman; Lewis, Raymond; Fant, Wallace

2003-01-01

The significant energy density of matter-antimatter annihilation is attractive to the designers of future space propulsion systems, with the potential to offer a highly compact source of power. Many propulsion concepts exist that could take advantage of matter-antimatter reactions, and current antiproton production rates are sufficient to support basic proof-of-principle evaluation of technology associated with antimatter- derived propulsion. One enabling technology for such experiments is portable storage of low energy antiprotons, allowing antiprotons to be trapped, stored, and transported for use at an experimental facility. To address this need, the Marshall Space Flight Center's Propulsion Research Center is developing a storage system referred to as the High Performance Antiproton Trap (HiPAT) with a design goal of containing 10(exp 12) particles for up to 18 days. The HiPAT makes use of an electromagnetic system (Penning- Malmberg design) consisting of a 4 Telsa superconductor, high voltage electrode structure, radio frequency (RF) network, and ultra high vacuum system. To evaluate the system normal matter sources (both electron guns and ion sources) are used to generate charged particles. The electron beams ionize gas within the trapping region producing ions in situ, whereas the ion sources produce the particles external to the trapping region and required dynamic capture. A wide range of experiments has been performed examining factors such as ion storage lifetimes, effect of RF energy on storage lifetime, and ability to routinely perform dynamic ion capture. Current efforts have been focused on improving the FW rotating wall system to permit longer storage times and non-destructive diagnostics of stored ions. Typical particle detection is performed by extracting trapped ions from HiPAT and destructively colliding them with a micro-channel plate detector (providing number and energy information). This improved RF system has been used to detect various

Técnicas moleculares para la detección e identificación de patógenos en alimentos: ventajas y limitaciones

OpenAIRE

Palomino-Camargo, Carolina; González-Muñoz, Yuniesky

2014-01-01

Las enfermedades transmitidas por alimentos, ocasionadas por microorganismos patógenos, constituyen un grave problema de salud pública a nivel mundial. Los métodos microbiológicos utilizados comúnmente en la detección de estos patógenos, de origen alimentario, son laboriosos y consume mucho tiempo. Esta situación, aunada a la demanda por resultados inmediatos y a los avances tecnológicos, ha conducido al desarrollo de una amplia gama de métodos rápidos en las últimas décadas. En base a esto, ...

Scheduling Additional Train Unit Services on Rail Transit Lines

OpenAIRE

Zhibin Jiang; Yuyan Tan; Özgür Yalçınkaya

2014-01-01

This paper deals with the problem of scheduling additional train unit (TU) services in a double parallel rail transit line, and a mixed integer programming (MIP) model is formulated for integration strategies of new trains connected by TUs with the objective of obtaining higher frequencies in some special sections and special time periods due to mass passenger volumes. We took timetable scheduling and TUs scheduling as an integrated optimization model with two objectives: minimizing travel ti...

Designing Robust Process Analytical Technology (PAT) Systems for Crystallization Processes: A Potassium Dichromate Crystallization Case Study

DEFF Research Database (Denmark)

Abdul Samad, Noor Asma Fazli Bin; Sin, Gürkan

2013-01-01

The objective of this study is to test and validate a Process Analytical Technology (PAT) system design on a potassium dichromate crystallization process in the presence of input uncertainties using uncertainty and sensitivity analysis. To this end a systematic framework for managing uncertaintie...

Individual and Synergetic Effects of Transit Service Improvement Strategies : Simulation and Validation

NARCIS (Netherlands)

West, J; Cats, O.

2017-01-01

Assessment of transit service improvements such as bus lanes, allowing boarding through all doors, and headway-based holding control requires detailed simulation capabilities. However, because the usage of models advanced enough to simultaneously analyze physical and operational measures has been

Process Analytical Technology (PAT): batch-to-batch reproducibility of fermentation processes by robust process operational design and control.

Science.gov (United States)

Gnoth, S; Jenzsch, M; Simutis, R; Lübbert, A

2007-10-31

The Process Analytical Technology (PAT) initiative of the FDA is a reaction on the increasing discrepancy between current possibilities in process supervision and control of pharmaceutical production processes and its current application in industrial manufacturing processes. With rigid approval practices based on standard operational procedures, adaptations of production reactors towards the state of the art were more or less inhibited for long years. Now PAT paves the way for continuous process and product improvements through improved process supervision based on knowledge-based data analysis, "Quality-by-Design"-concepts, and, finally, through feedback control. Examples of up-to-date implementations of this concept are presented. They are taken from one key group of processes in recombinant pharmaceutical protein manufacturing, the cultivations of genetically modified Escherichia coli bacteria.

Linking ecosystem services with state-and-transition models to evaluate rangeland management decisions

Science.gov (United States)

Lohani, S.; Heilman, P.; deSteiguer, J. E.; Guertin, D. P.; Wissler, C.; McClaran, M. P.

2014-12-01

Quantifying ecosystem services is a crucial topic for land management decision making. However, market prices are usually not able to capture all the ecosystem services and disservices. Ecosystem services from rangelands, that cover 70% of the world's land area, are even less well-understood since knowledge of rangelands is limited. This study generated a management framework for rangelands that uses remote sensing to generate state and transition models (STMs) for a large area and a linear programming (LP) model that uses ecosystem services to evaluate natural and/or management induced transitions as described in the STM. The LP optimization model determines the best management plan for a plot of semi-arid land in the Empire Ranch in southeastern Arizona. The model allocated land among management activities (do nothing, grazing, fire, and brush removal) to optimize net benefits and determined the impact of monetizing environmental services and disservices on net benefits, acreage allocation and production output. The ecosystem services under study were forage production (AUM/ac/yr), sediment (lbs/ac/yr), water runoff (inches/yr), soil loss (lbs/ac/yr) and recreation (thousands of number of visitors/ac/yr). The optimization model was run for three different scenarios - private rancher, public rancher including environmental services and excluding disservices, and public rancher including both services and disservices. The net benefit was the highest for the public rancher excluding the disservices. A result from the study is a constrained optimization model that incorporates ecosystem services to analyze investments on conservation and management activities. Rangeland managers can use this model to understand and explain, not prescribe, the tradeoffs of management investments.

PAT challenges routine techniques on defect spectroscopy in material science

International Nuclear Information System (INIS)

Badawi, E.A.

2005-01-01

Atomic or Point Defects are the most simple defects in solids. Due to the small size their direct observation by the routine techniques is not possible. A single type of defects (thermal defect) was observed in the quenching process. Using the Arrhenius method and threshold method we recommended the accurate both method of treatments. The calculated values for formation enthalpies and self-diffusion using positron lifetime and Doppler broadening in a good agreement in (A356.0) and (A413.1). Specifically it is show how PAT detect defect concentrations, (formation- migration) enthalpies and grain size for the material under investigation. Most of the these data are reported

Plutonium air transportable package Model PAT-1. Safety analysis report

International Nuclear Information System (INIS)

1978-02-01

The document is a Safety Analysis Report for the Plutonium Air Transportable Package, Model PAT-1, which was developed by Sandia Laboratories under contract to the Nuclear Regulatory Commission (NRC). The document describes the engineering tests and evaluations that the NRC staff used as a basis to determine that the package design meets the requirements specified in the NRC ''Qualification Criteria to Certify a Package for Air Transport of Plutonium'' (NUREG-0360). By virtue of its ability to meet the NRC Qualification Criteria, the package design is capable of safely withstanding severe aircraft accidents. The document also includes engineering drawings and specifications for the package. 92 figs, 29 tables

Gérmenes patógenos aislados en niños con infecciones respiratorias a repetición

Directory of Open Access Journals (Sweden)

Yoenny Peña García

2015-01-01

Full Text Available Las infecciones respiratorias agudas son la causa más frecuente de morbilidad y de elevada mortalidad en el mundo, particularmente en los países en desarrollo. Se realizó un estudio descriptivo de corte transversal, para caracterizar a los niños con infecciones respiratorias a repetición, según los gérmenes patógenos aislados, en el círculo infantil “Flores de la Vida” del municipio de Puerto Padre, en el período de abril a mayo de 2014. Se trabajó con los niños de los salones de segundo, tercero y cuarto año de vida, distribuidos según edad y sexo, a los que se les identificaron los gérmenes patógenos aislados en exudados nasofaríngeos. La información se obtuvo del departamento de microbiología del Centro Municipal de Higiene y Epidemiología. Se obtuvieron los siguientes resultados: el grupo de edad más frecuente fue el de dos años, que representó el 45 % de la muestra y se correspondió con la media de la edad. El 62,5 % de la muestra de estudio correspondió al sexo masculino. Los gérmenes patógenos aislados con mayor frecuencia fueron: el Streptococcus pneumoneae, para un 83,9 %, el Streptococcus B hemolítico, para un 7,1 % y el Haemophillus inflienzae para un 5,4 %

Design and Fabrication of Cryostat Interface and Electronics for High Performance Antimatter Trap (HI-PAT)

Science.gov (United States)

Smith, Gerald A.

1999-01-01

Included in Appendix I to this report is a complete set of design and assembly schematics for the high vacuum inner trap assembly, cryostat interfaces and electronic components for the MSFC HI-PAT. Also included in the final report are summaries of vacuum tests, and electronic tests performed upon completion of the assembly.

UN_PAT: a software for calculating transient grounding potential

Directory of Open Access Journals (Sweden)

Johny Hernán Montaña

2006-09-01

Full Text Available This paper presents results from work done at the National University of Colombia and from a PhD thesis written there. This work was aimed at implementing software for analysing the transient behaviour of any configuration of grounding system buried in lineal, homogeneous and isotropic soil. The hybrid electromagnetic model (HEM was used because it presents high versatility and low computation time. The UN_PAT software was written in C++; it used free libraries with the aim of being free software so that it could be modified and improved in future work. The software results were validated with other software, with results from another analysis model and experimental results; some of these comparisons are given in this paper.

Characteristics of Patients Accepting and Declining Participation in a Transition of Care Service Provided by a Community Pharmacy

Directory of Open Access Journals (Sweden)

Julianne M Kowalski, PharmD

2017-02-01

Full Text Available Objectives: To identify characteristics of patients who accepted or declined an appointment for a transition of care service provided by an independent community pharmacist and identify the most common reasons patients declined the service. Methods: A transition of care service was offered by a community pharmacy to patients discharged to home from the cardiac unit of a local hospital. The community pharmacist approached patients prior to discharge for recruitment into the service. Outcomes included service acceptance rate, LACE score at discharge, readmission risk category, age, gender, geographic home location, and reason for refusing the service. Descriptive statistics and logistic regression were used to compare characteristics between those who accepted or declined the service. Reasons for decline were assessed using content analysis. Results: Of the 87 patients that were included in the analysis, 21 patients received the transitions of care service (24.1%. None of the characteristics were found to be statistically significant between patients who received or declined the service. Patients at a moderate risk for readmission seemed more likely to accept the pharmacist-run appointment than those at high risk (27.9% vs 15.3%; P = 0.29. Of the 66 patients who declined, 51 gave a reason (77.3%. Thirty-nine patients saw no benefit (76.5%, five patients had perceived barriers (10%, and seven patients gave reasons that fell into both categories (13.5%. Conclusions: This evaluation did not find a statistically significant difference in characteristics between those patients who accepted or declined participation in a pharmacist-run transition of care service. Patients may be less likely to accept pharmacist-run transition of care appointments primarily due to no perceived benefits. To increase participation, we need to understand the patient’s health beliefs, educate patients on pharmacy services, and implement changes to recruit potential

Within-person analysis of welfare transitions in a longitudinal panel survey reveals change in mental health service use.

Science.gov (United States)

Pymont, C; Schofield, T P; Butterworth, P

2017-12-01

While international research shows that receipt of welfare benefits is associated with poor mental health, less is known about the relationship between welfare receipt and mental health service use. We investigate whether within-person change in welfare recipient status is associated with change in mental health service use. Analysis of two waves of data from an Australian national household survey. Random- and fixed-effect models considered the effect of change in welfare receipt status, and assessed whether change in mental health service use differed by type of welfare benefit or the direction of welfare transition. Individuals were more likely to report greater mental health service use at times of welfare receipt. These associations were attenuated, but remained significant, after adjusting for mental health. Increased health service use was not tied to specific types of welfare benefits. The increase in mental health service use associated with a transition onto welfare benefits was much greater than the decline in service use associated with the transition off benefits. Within individuals, welfare receipt is associated with greater mental health service use. While this does reflect poorer mental health at the time of welfare receipt, other factors seem to facilitate health service use. © The Author 2016. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Transition from children's to adult services for young adults with life-limiting conditions: A realist review of the literature.

Science.gov (United States)

Kerr, Helen; Price, Jayne; Nicholl, Honor; O'Halloran, Peter

2017-11-01

Improvements in care and treatment have led to more young adults with life-limiting conditions living beyond childhood, which means they must make the transition from children's to adult services. This has proved a challenging process for both young adults and service providers, with complex transition interventions interacting in unpredictable ways with local contexts. To explain how intervention processes interact with contextual factors to help transition from children's to adult services for young adults with life-limiting conditions. Systematic realist review of the literature. Literature was sourced from four electronic databases: Embase, MEDLINE, Science Direct and Cochrane Library from January 1995 to April 2016. This was supplemented with a search in Google Scholar and articles sourced from reference lists of included papers. Data were extracted using an adapted standardised data extraction tool which included identifying information related to interventions, mechanisms, contextual influences and outcomes. Two reviewers assessed the relevance of papers based on the inclusion criteria. Methodological rigor was assessed using the relevant Critical Appraisal Skills Programme tools. 78 articles were included in the review. Six interventions were identified related to an effective transition to adult services. Contextual factors include the need for children's service providers to collaborate with adult service providers to prepare an environment with knowledgeable staff and adequate resources. Mechanisms triggered by the interventions include a sense of empowerment and agency amongst all stakeholders. Early planning, collaboration between children's and adult service providers, and a focus on increasing the young adults' confidence in decision-making and engaging with adult services, are vital to a successful transition. Interventions should be tailored to their context and focused not only on organisational procedures but on equipping young adults, parents

Exploring the need for Transition Readiness Scales within cystic fibrosis services: A qualitative descriptive study.

Science.gov (United States)

Bourke, Mary; Houghton, Catherine

2018-07-01

To explore healthcare professionals' and patients' perceptions of the potential use of a Transition Readiness Scale in cystic fibrosis care. This included an examination of barriers and facilitators to its implementation along with the identification of key items to include in a Transition Readiness Scale. Due to increasing life expectancy and improved quality of life, more adolescents with cystic fibrosis are transitioning from paediatric to adult health care. To assess and correctly manage this transition, a more structured approach to transition is advocated. This can be achieved using a Transition Readiness Scale to potentially identify or target areas of care in which the adolescent may have poor knowledge. These key items include education, developmental readiness taking into account relationships, reproduction, future plans and self-management skills. Existing tools to gauge readiness concentrate mainly on education and self-care needs assessment as their key items. Currently, there is no specific cystic fibrosis Transition Readiness Scale in use in Ireland or internationally. The study used a descriptive qualitative design. Data were collected using semi-structured interviews (n = 8) and analysed using a thematic approach. The findings identified the potential benefits of this tool and second the resources which need to be in place before its development and implementation into cystic fibrosis services. Transition Readiness Scales have substantial relevance with cystic fibrosis services emphasising the importance of establishing the necessary resources prior to its implementation. These were identified as more staff, a dedicated private space and staff training and education. Significant resources are needed to fully integrate Transition Readiness Scales in practice. The study findings suggest multidisciplinary collaborations, and patient engagement is pivotal in planning and easing the transition process for adolescents with cystic fibrosis. © 2018 The

NeuPAT: an intranet database supporting translational research in neuroblastic tumors.

Science.gov (United States)

Villamón, Eva; Piqueras, Marta; Meseguer, Javier; Blanquer, Ignacio; Berbegall, Ana P; Tadeo, Irene; Hernández, Vicente; Navarro, Samuel; Noguera, Rosa

2013-03-01

Translational research in oncology is directed mainly towards establishing a better risk stratification and searching for appropriate therapeutic targets. This research generates a tremendous amount of complex clinical and biological data needing speedy and effective management. The authors describe the design, implementation and early experiences of a computer-aided system for the integration and management of data for neuroblastoma patients. NeuPAT facilitates clinical and translational research, minimizes the workload in consolidating the information, reduces errors and increases correlation of data through extensive coding. This design can also be applied to other tumor types. Copyright © 2012 Elsevier Ltd. All rights reserved.

The LIFEspan model of transitional rehabilitative care for youth with disabilities: healthcare professionals' perspectives on service delivery.

Science.gov (United States)

Hamdani, Yani; Proulx, Meghann; Kingsnorth, Shauna; Lindsay, Sally; Maxwell, Joanne; Colantonio, Angela; Macarthur, Colin; Bayley, Mark

2014-01-01

LIFEspan is a service delivery model of continuous coordinated care developed and implemented by a cross-organization partnership between a pediatric and an adult rehabilitation hospital. Previous work explored enablers and barriers to establishing the partnership service. This paper examines healthcare professionals' (HCPs') experiences of 'real world' service delivery aimed at supporting transitional rehabilitative care for youth with disabilities. This qualitative study - part of an ongoing mixed method longitudinal study - elicited HCPs' perspectives on their experiences of LIFEspan service delivery through in-depth interviews. Data were categorized into themes of service delivery activities, then interpreted from the lens of a service integration/coordination framework. Five main service delivery themes were identified: 1) addressing youth's transition readiness and capacities; 2) shifting responsibility for healthcare management from parents to youth; 3) determining services based on organizational resources; 4) linking between pediatric and adult rehabilitation services; and, 5) linking with multi-sector services. LIFEspan contributed to service delivery activities that coordinated care for youth and families and integrated inter-hospital services. However, gaps in service integration with primary care, education, social, and community services limited coordinated care to the rehabilitation sector. Recommendations are made to enhance service delivery using a systems/sector-based approach.

The proton-coupled amino acid transporter hPAT1 is the main transporter involved in vigabatrin uptake in intestinal Caco-2 cells

DEFF Research Database (Denmark)

Nøhr, Martha Kampp; Hansen, Steen Honore'; Brodin, Birger

2012-01-01

transporter hPAT1. The aim of the project was to identify if transporters are involved in cellular uptake of vigabatrin in Caco-2 cells. Methods: The uptake rate of vigabatrin was measured in Caco-2 cells at pH 6.0 or 7.4 for 15 min after application of 0.1 – 25.0 mM vigabatrin. The inhibitory effect...... of selected amino acids and -derivatives on the apical vigabatrin uptake in Caco-2 cells was investigated. Vigabatrin samples were analyzed using liquid chromatography (LC) coupled to a mass selective detector (MSD). Results: The uptake rate of vigabatrin in Caco-2 cells was pH-dependent. The uptake...... of vigabatrin was saturable at pH 6.0 with a Michaelis constant, Km of 12.7 ± 3.7 mM and a maximal flux, Jmax of 3.7 ± 0.5 nmol•min-1•cm-2. The presences of hPAT1 ligands significantly inhibited the uptake of vigabatrin in Caco-2 cells at pH 6.0, whereas hPAT1 non-ligands did not. Discussion: The saturability...

Latent transition analysis of pre-service teachers' efficacy in mathematics and science

Science.gov (United States)

Ward, Elizabeth Kennedy

This study modeled changes in pre-service teacher efficacy in mathematics and science over the course of the final year of teacher preparation using latent transition analysis (LTA), a longitudinal form of analysis that builds on two modeling traditions (latent class analysis (LCA) and auto-regressive modeling). Data were collected using the STEBI-B, MTEBI-r, and the ABNTMS instruments. The findings suggest that LTA is a viable technique for use in teacher efficacy research. Teacher efficacy is modeled as a construct with two dimensions: personal teaching efficacy (PTE) and outcome expectancy (OE). Findings suggest that the mathematics and science teaching efficacy (PTE) of pre-service teachers is a multi-class phenomena. The analyses revealed a four-class model of PTE at the beginning and end of the final year of teacher training. Results indicate that when pre-service teachers transition between classes, they tend to move from a lower efficacy class into a higher efficacy class. In addition, the findings suggest that time-varying variables (attitudes and beliefs) and time-invariant variables (previous coursework, previous experiences, and teacher perceptions) are statistically significant predictors of efficacy class membership. Further, analyses suggest that the measures used to assess outcome expectancy are not suitable for LCA and LTA procedures.

Overview of PAT process analysers applicable in monitoring of film coating unit operations for manufacturing of solid oral dosage forms.

Science.gov (United States)

Korasa, Klemen; Vrečer, Franc

2018-01-01

Over the last two decades, regulatory agencies have demanded better understanding of pharmaceutical products and processes by implementing new technological approaches, such as process analytical technology (PAT). Process analysers present a key PAT tool, which enables effective process monitoring, and thus improved process control of medicinal product manufacturing. Process analysers applicable in pharmaceutical coating unit operations are comprehensibly described in the present article. The review is focused on monitoring of solid oral dosage forms during film coating in two most commonly used coating systems, i.e. pan and fluid bed coaters. Brief theoretical background and critical overview of process analysers used for real-time or near real-time (in-, on-, at- line) monitoring of critical quality attributes of film coated dosage forms are presented. Besides well recognized spectroscopic methods (NIR and Raman spectroscopy), other techniques, which have made a significant breakthrough in recent years, are discussed (terahertz pulsed imaging (TPI), chord length distribution (CLD) analysis, and image analysis). Last part of the review is dedicated to novel techniques with high potential to become valuable PAT tools in the future (optical coherence tomography (OCT), acoustic emission (AE), microwave resonance (MR), and laser induced breakdown spectroscopy (LIBS)). Copyright © 2017 Elsevier B.V. All rights reserved.

Evaluation of Outcomes in Adolescent Inflammatory Bowel Disease Patients Following Transfer From Pediatric to Adult Health Care Services: Case for Transition.

Science.gov (United States)

Cole, Rebecca; Ashok, Dhandapani; Razack, Abdul; Azaz, Amer; Sebastian, Shaji

2015-08-01

We aimed to evaluate the impact of a transition service on clinical and developmental outcomes in adolescent Inflammatory Bowel Disease (IBD) patients on transfer to adult health care services. We reviewed the records of IBD patients diagnosed in pediatric care following their transfer/attendance to the adult IBD service. The data on patients who attended the transition service were compared with those who did not pass through the transition service. Seventy-two patients were included in the study 41M and 31F. Forty-four patients went through the transition system (Group A), and 28 had no formalized transition arrangement before transfer (Group B). A significantly higher number of Group B patients needed surgery within 2 years of transfer when compared with patients in Group A (46% vs. 25%, p = .01). Sixty-one percent of patients in Group B needed at least one admission within 2 years of transfer when compared with 29% of Group A patients (p = .002). Nonattendance at clinics was higher in Group B patients with 78% having at least one nonattendance, whereas 29% of Group A failed to attend at least one appointment (p = .001). In addition, drug compliance rates were higher in the transition group when compared with Group B (89% and 46%, respectively; p = .002). A higher proportion of transitioned patients achieved their estimated maximum growth potential when completing adolescence. There was a trend toward higher dependence on opiates and smoking in Group B patients. In adolescent IBD patients, transition care is associated with better disease specific and developmental outcomes. Prospective studies of different models of transition care in IBD are needed. Copyright © 2015 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

Reklāmas ietekme uz patērētāju izvēles veikšanā

OpenAIRE

Asejevs, Aleksandrs

2012-01-01

Bakalaura darba tēma izvēlēta „Reklāmas ietekme uz patērētāju izvēles veikšanā”. Pastiprinoties konkurencei valstu iekšzemes tirgū, uzņēmumi savas preces un pakalpojumus virza globālajā tirgū. Starptautiskajā mārketingā reklāma tiek izmantota kā viens no mārketinga komunikācijas līdzekļiem, ar kura palīdzību uzņēmumi patērētajiem virzītu savas preces un pakalpojumus. Darba mērķis: balstoties uz veiktās aptaujas rezultātiem, izstrādāt priekšlikumus reklāmas pilnveidošanai Latvijā. Lai...

Strategic funding priorities in the pharmaceutical sciences allied to Quality by Design (QbD) and Process Analytical Technology (PAT)

DEFF Research Database (Denmark)

Aksu, Buket; De Beer, Thomas; Folestad, Staffan

2012-01-01

however have the potential to provide considerable challenges to the establishment of cost effective and robust supply chains. To guarantee product quality and surety of supply for essential medicines it is necessary that manufacturing science keeps pace with advances in pharmaceutical R......Substantial changes in Pharmaceutical R&D strategy are required to address existing issues of low productivity, imminent patent expirations and pressures on pricing. Moves towards personalized healthcare and increasing diversity in the nature of portfolios including the rise of biopharmaceuticals......&D. In this position paper, the EUFEPS QbD and PAT Sciences network make recommendations that European industry, academia and health agencies focus attention on delivering step changes in science and technology in a number of key themes. These subject areas, all underpinned by the sciences allied to QbD and PAT...

Service provider perceptions of transitioning from audio to video capability in a telehealth system: a qualitative evaluation

OpenAIRE

Clay-Williams, Robyn; Baysari, Melissa; Taylor, Natalie; Zalitis, Dianne; Georgiou, Andrew; Robinson, Maureen; Braithwaite, Jeffrey; Westbrook, Johanna

2017-01-01

Background Telephone consultation and triage services are increasingly being used to deliver health advice. Availability of high speed internet services in remote areas allows healthcare providers to move from telephone to video telehealth services. Current approaches for assessing video services have limitations. This study aimed to identify the challenges for service providers associated with transitioning from audio to video technology. Methods Using a mixed-method, qualitative approach, w...

Interactions between Upf1 and the decapping factors Edc3 and Pat1 in Saccharomyces cerevisiae.

Directory of Open Access Journals (Sweden)

Kylie D Swisher

Full Text Available In Saccharomyces cerevisiae, mRNA transcripts with premature termination codons are targeted for deadenylation independent decapping and 5' to 3' decay in a quality control pathway termed nonsense-mediated decay (NMD. Critical factors in NMD include Upf1, Upf2, and Upf3, as well as the decapping enzyme, Dcp2/Dcp1. Loss of Upf2 or Upf3 leads to the accumulation of not only Upf1 and Dcp2 in P-bodies, but also of the decapping-activators Pat1, Dhh1, and Lsm1. An interaction between Upf1 and Dcp2 has been identified, which might recruit Dcp2 to the NMD decapping complex. To determine the nature and significance of the Dcp2-Upf1 interaction, we utilized the yeast two-hybrid assay to assess Upf1 interactions with various mRNA decapping factors. We find that although Dcp2 can interact with Upf1, this interaction is indirect and is largely dependent on the Edc3 protein, which interacts with the N-terminal domain of Upf1 at an overlapping, but not identical, site as Upf2. We also found that Pat1 has an independent two-hybrid interaction with the N-terminus of Upf1. Assessment of both reporter and endogenous NMD transcripts suggest that the decapping stimulators, including Edc3 and Pat1, as well as Edc1 and Edc2, are not essential for NMD under normal conditions. This work defines a larger decapping complex involved in NMD, but indicates that components of that complex are not required for general NMD and might either regulate a subset of NMD transcripts or be essential for proper NMD under different environmental conditions.

The medical libraries of Vietnam--a service in transition.

Science.gov (United States)

Brennen, P W

1992-07-01

The medical libraries of Vietnam maintain high profiles within their institutions and are recognized by health care professionals and administrators as an important part of the health care system. Despite the multitude of problems in providing even a minimal level of medical library services, librarians, clinicians, and researchers nevertheless are determined that enhanced services be made available. Currently, services can be described as basic and unsophisticated, yet viable and surprisingly well organized. The lack of hard western currency required to buy materials and the lack of library technology will be major obstacles to improving information services. Vietnam, like many developing nations, is about to enter a period of technological upheaval, which ultimately will result in a transition from the traditional library limited by walls to a national resource that will rely increasingly on electronic access to international knowledge networks. Technology such as CD-ROM, Integrated Services Digital Network (ISDN), and satellite telecommunication networks such as Internet can provide the technical backbone to provide access to remote and widely distributed electronic databases to support the information needs of the health care community. Over the long term, access to such databases likely will be cost-effective, in contrast to the assuredly astronomical cost of building a comparable domestic print collection. The advent of new, low-cost electronic technologies probably will revolutionize health care information services in developing nations. However, for the immediate future, the medical libraries of Vietnam will require ongoing sustained support from the international community, so that minimal levels of resources will be available to support the information needs of the health care community. It is remarkable, and a credit to the determination of Vietnam's librarians that, in a country with a legacy of war, economic deprivation, and international isolation

Organising Sustainable Transition: Understanding the Product, Project and Service Domain of the Built Environment

DEFF Research Database (Denmark)

Thuesen, Christian; Koch-Ørvad, Nina; Maslesa, Esmir

2016-01-01

of three generic domains - the Project, Product and Service domain - with widely different markets, companies, business models and regulation. Besides identifying the characteristics of the different domains, the findings show that these domains are interdependent, but largely live their own lives......Sustainable transition of the built environment con struction industry is challenging the existing construction practices and business models. This article presents a framework for understanding and facilitating sustainable transition in the built environment. The framework was developed through...

Técnicas moleculares para la detección e identificación de patógenos en alimentos: ventajas y limitaciones

Directory of Open Access Journals (Sweden)

Carolina Palomino-Camargo

2014-09-01

Full Text Available Las enfermedades transmitidas por alimentos, ocasionadas por microorganismos patógenos, constituyen un grave problema de salud pública a nivel mundial. Los métodos microbiológicos utilizados comúnmente en la detección de estos patógenos, de origen alimentario, son laboriosos y consume mucho tiempo. Esta situación, aunada a la demanda por resultados inmediatos y a los avances tecnológicos, ha conducido al desarrollo de una amplia gama de métodos rápidos en las últimas décadas. En base a esto, la presente revisión describe las ventajas y limitaciones de los principales métodos moleculares utilizados en la detección e identificación de microorganismos patógenos transmitidos por alimentos. Para ello, se consideró la actualidad de la información consultada, el análisis objetivo de la temática y su alcance. La literatura reciente reporta un número significativo de técnicas moleculares, alternativas, sensibles y selectivas para la detección, enumeración e identificación de microorganismos patógenos en alimentos, siendo la reacción en cadena de la polimerasa (PCR la plataforma más popular, mientras que la secuenciación de alto rendimiento se perfila como una técnica de gran aplicabilidad a futuro. Sin embargo, aun con todas las ventajas que ofrecen estas novedosas metodologías, no se deben pasar por alto sus limitaciones. Así, por ejemplo, los métodos moleculares no constituyen protocolos estandarizados, lo que dificulta su utilización en algunos casos. Por esta razón se debe trabajar arduamente para superar tales limitaciones y mejorar la aplicación de estas técnicas en matrices tan complejas como los sistemas alimenticios.

Transition from an asylum seeker-specific health service to mainstream primary care for community-based asylum seekers: a qualitative interview study.

Science.gov (United States)

Fair, Genevieve L; Harris, Mark F; Smith, Mitchell M

2018-03-15

Transition of asylum seekers from special-purpose health services to mainstream primary care is both necessary and difficult. This study explores the issues encountered by asylum seekers undergoing this transition in Sydney, Australia. Qualitative semistructured interviews were conducted with nine asylum seeker patients and nine staff working in the sector. Asylum seekers faced significant challenges in the transition to mainstream primary care. Contributing factors included the complexity of health and immigration systems, the way in which asylum seeker-specific services provide care, lack of understanding and accommodation by mainstream general practioner (GP) services, asylum seekers' own lack of understanding of the health system, mental illness, and social and financial pressures. There is a need for better preparation of asylum seekers for the transition to mainstream primary care. Mainstream GPs and other providers need more education and support so that they can better accommodate the needs of asylum seeker patients. This is an important role for Australia's refugee health services and Primary Health Networks.

Introducing uncertainty analysis of nucleation and crystal growth models in Process Analytical Technology (PAT) system design of crystallization processes.

Science.gov (United States)

Samad, Noor Asma Fazli Abdul; Sin, Gürkan; Gernaey, Krist V; Gani, Rafiqul

2013-11-01

This paper presents the application of uncertainty and sensitivity analysis as part of a systematic model-based process monitoring and control (PAT) system design framework for crystallization processes. For the uncertainty analysis, the Monte Carlo procedure is used to propagate input uncertainty, while for sensitivity analysis, global methods including the standardized regression coefficients (SRC) and Morris screening are used to identify the most significant parameters. The potassium dihydrogen phosphate (KDP) crystallization process is used as a case study, both in open-loop and closed-loop operation. In the uncertainty analysis, the impact on the predicted output of uncertain parameters related to the nucleation and the crystal growth model has been investigated for both a one- and two-dimensional crystal size distribution (CSD). The open-loop results show that the input uncertainties lead to significant uncertainties on the CSD, with appearance of a secondary peak due to secondary nucleation for both cases. The sensitivity analysis indicated that the most important parameters affecting the CSDs are nucleation order and growth order constants. In the proposed PAT system design (closed-loop), the target CSD variability was successfully reduced compared to the open-loop case, also when considering uncertainty in nucleation and crystal growth model parameters. The latter forms a strong indication of the robustness of the proposed PAT system design in achieving the target CSD and encourages its transfer to full-scale implementation. Copyright © 2013 Elsevier B.V. All rights reserved.

The Effects of Organizational Culture on Mental Health Service Engagement of Transition Age Youth.

Science.gov (United States)

Kim, HyunSoo; Tracy, Elizabeth M; Biegel, David E; Min, Meeyoung O; Munson, Michelle R

2015-10-01

Nationwide, there is a growing concern in understanding mental health service engagement among transition age youth. The ecological perspective suggests that there are multiple barriers to service engagement which exist on varying levels of the ecosystem. Based on the socio-technical theory and organizational culture theory, this study examined the impact of organization-level characteristics on perceived service engagement and the moderating role of organizational culture on practitioner-level characteristics affecting youth service engagement. A cross-sectional survey research design was used to address the research questions. The data were collected from 279 practitioners from 27 mental health service organizations representing three major metropolitan areas in Ohio. Hierarchical linear modeling was used to address a nested structure. Findings revealed that location of organization, service setting, and organizational culture had significant effects on the continuation of services. In addition, the relationship between service coordination and resource knowledge and service engagement was moderated by organizational culture.

Gender Differences in Vocational Rehabilitation Service Predictors of Successful Competitive Employment for Transition-Aged Individuals with Autism

Science.gov (United States)

Sung, Connie; Sánchez, Jennifer; Kuo, Hung-Jen; Wang, Chia-Chiang; Leahy, Michael J.

2015-01-01

As males and females with autism spectrum disorder (ASD) experience different symptomology, their needs for vocational rehabilitation (VR) are unique as they transition into adulthood. This study examined the effects of gender differences in VR service predictors on employment outcomes for transition-aged individuals with ASD. A total of 1696…

Online transit trip planner for small agencies using Google Transit : final deployment package.

Science.gov (United States)

2011-09-01

Google Transit is a public transportation trip planner that enables travelers to obtain information regarding available transit services between a : given origin and given destination. While transit agencies can publish their service information onto...

Introducing uncertainty analysis of nucleation and crystal growth models in Process Analytical Technology (PAT) system design of crystallization processes

DEFF Research Database (Denmark)

Abdul Samad, Noor Asma Fazli Bin; Sin, Gürkan; Gernaey, Krist

2013-01-01

This paper presents the application of uncertainty and sensitivity analysis as part of a systematic modelbased process monitoring and control (PAT) system design framework for crystallization processes. For the uncertainty analysis, the Monte Carlo procedure is used to propagate input uncertainty...

Transition from an asylum seeker–specific health service to mainstream primary care for community-based asylum seekers: a qualitative interview study

Directory of Open Access Journals (Sweden)

Genevieve L Fair

2018-03-01

Full Text Available Background and aim: Transition of asylum seekers from special-purpose health services to mainstream primary care is both necessary and difficult. This study explores the issues encountered by asylum seekers undergoing this transition in Sydney, Australia. Methods: Qualitative semistructured interviews were conducted with nine asylum seeker patients and nine staff working in the sector. Results: Asylum seekers faced significant challenges in the transition to mainstream primary care. Contributing factors included the complexity of health and immigration systems, the way in which asylum seeker–specific services provide care, lack of understanding and accommodation by mainstream general practioner (GP services, asylum seekers’ own lack of understanding of the health system, mental illness, and social and financial pressures. Conclusions: There is a need for better preparation of asylum seekers for the transition to mainstream primary care. Mainstream GPs and other providers need more education and support so that they can better accommodate the needs of asylum seeker patients. This is an important role for Australia’s refugee health services and Primary Health Networks.

Human induced discharge diversion in a tropical delta and its environmental implications: The Patía River, Colombia

Science.gov (United States)

Restrepo, Juan D.; Kettner, Albert

2012-03-01

SummaryThe Patía River, the number one in terms of sediment yield ˜1500 t km-2 yr-1 draining the western South America, has the most extensive and well developed delta on the Pacific coast, measuring 1700 km2. During the Holocene, nature forced the Patía delta to the south; however, a major water diversion, starting in 1972, diverted the Patía flow to the Sanguianga River, the latter, a small stream draining internal lakes from the Pacific lowlands. This human induced discharge diversion shifted the active delta plain back to the north and changed the northern estuarine system into an active delta plain. Overall, major environmental consequences of this discharge diversion in terms of morphological changes along the delta coast and distributary channels, are evidenced by: (1) coastal retreat along the abandoned delta lobe; 63% of the southern shoreline is retreating at maximum rates of 7 m yr-1, with a corresponding coastal land loss of 106 m yr-1; (2) transgressive barrier islands with exposed peat soils in the surf zone; (3) abandonment of former active distributaries in the southern delta plain with associated closing of inlets and formation of ebb tidal deltas; (4) breaching events on barrier islands; and (5) distributary channel accretion in the northern delta plain by morphological processes such as sedimentation (also in crevasses), overbank flow, increasing width of levees, interdistributary channel fill, and colonization of pioneer mangrove. The Sanguianga Mangrove National Park (SMNP), the largest mangrove reserve in Colombia, measuring 800 km2, lies in this former estuary, where major hydrologic and sedimentation changes are occurring. Observed environmental changes in the SMNP, include (1) seaward advance of the sub-aqueous delta front at the Sanquianga inlet evidenced by an increase in tidal flat area from 5.4 Mm2 in 1986 to 14 Mm2 in 2001; (2) freshening conditions in the Sanguianga distributary channel, a hydrologic change that has shifted the

An Application of X-ray Fluorescence as Process Analytical Technology (PAT) to Monitor Particle Coating Processes.

Science.gov (United States)

Nakano, Yoshio; Katakuse, Yoshimitsu; Azechi, Yasutaka

2018-03-30

An attempt to apply X-ray Fluorescence (XRF) analysis to evaluate small particle coating process as a Process Analytical Technologies (PAT) was made. The XRF analysis was used to monitor coating level in small particle coating process with at-line manner. The small particle coating process usually consists of multiple coating processes. This study was conducted by a simple coating particles prepared by first coating of a model compound (DL-methionine) and second coating by talc on spherical microcrystalline cellulose cores. The particles with two layered coating are enough to demonstrate the small particle coating process. From the result by the small particle coating process, it was found that the XRF signal played different roles, resulting that XRF signals by first coating (layering) and second coating (mask coating) could demonstrate the extent with different mechanisms for the coating process. Furthermore, the particle coating of the different particle size has also been investigated to evaluate size effect of these coating processes. From these results, it was concluded that the XRF could be used as a PAT in monitoring particle coating processes and become powerful tool in pharmaceutical manufacturing.

[The transition process from paediatric to adult services: A perspective from hospitalised adolescent sufferers of chronic diseases].

Science.gov (United States)

Inostroza Quezada, Carolina; Correa Venegas, María Loreto; Besoain Arrau, Carolina; Reinoso Medinelli, Alejandro; Velarde Lizama, Macarena; Valenzuela Mujica, María Teresa; Bedregal García, Paula; Zubarew Gurtchin, Tamara

2016-01-01

Chronic illnesses during adolescence are a big challenge for the patient, his or her family, and health care providers. The transition from paediatric health services to adult health services involves a programmed and planned transfer process of adolescent sufferers of chronic illnesses, in order to maintain a high quality of life and bio-psycho-social development. There is currently no transition model. The objective of the study is to understand the transition process from the perspective of hospitalised adolescents to collaborate towards the design of a model that meets the needs studied. Semi-structured interviews with 13 adolescent sufferers of chronic illnesses, hospitalised in two healthcare centres in Santiago, Chile, in one analytical-relational study, supported by qualitative methodology. In the analysis, 5 major themes stand out: experience of living with the illness, the importance of the doctor-patient relationship, the concept of limited autonomy to the pharmacology, the absence of the transition process as such, and the identification of barriers and needs for an adequate transition. This study is new in Chile in that it explores the phenomenom of the transition of adolescents with chronic illnesses. It emphasises the need to reinforce the concept of self-care and autonomy from early stages of care, and the importance of early planning of a healthy transition process, in accordance to the detected needs of the adolescents themselves. Copyright © 2015. Publicado por Elsevier España, S.L.U.

Zīmola vērtība no patērētāju perspektīvas sporta apģerbu un apavu tirgū.

OpenAIRE

Kadakovska, Agnese

2017-01-01

Bakalaura darba tēma ir “Zīmola vērtība no patērētāju perspektīvas sporta apģērbu un apavu tirgū”. Bakalaura darba mērķis ir pamatojoties uz izpētīto teorētisko informāciju par zīmola vērtības no patērētāju perspektīvas veidošanu, identificēt patērētāju skatījumā vērtīgākos sporta apģērbu un apavu tirgus zīmolus Latvijā un izstrādāt priekšlikumus to vērtības palielināšanai. Bakalaura darbs sastāv no ievada, 3 nodaļām, secinājumiem un priekšlikumiem, izmantotās literatūras saraksta un pielikum...

An Investigation of Incorporating Dialogical Argumentation into Peer Instruction (PI for Pre-Service Teacher Learning of Current Electricity

Directory of Open Access Journals (Sweden)

Aina Jacob Kola

2017-05-01

Full Text Available The study is a quasi-experimental research employing the pretest-posttest design. 52 pre-service teachers from a college of education were sampled with 26 pre-service teachers in both the control group (CG and experimental group (EG. The instruments used to collect data were Physics Achievement Test (PAT, Peer Instruction Dialogical Argumentation Questionnaire (PIDAQ, and Adopted Physics ConcepTest (APC for teaching the experimental group. The instruments were validated by experts in science education and physics. The reliability of the PAT, based on a pilot test conducted, shows that the Cronbach’s alpha coefficient is 0.876. The data obtained were analyzed using t-test, Analysis of Covariance (ANCOVA, and descriptive statistics. Findings revealed that the incorporation of DA into PI has an impact on the students’ learning of current electricity. The study considered some implications of the findings on the teaching and learning of physics.

How can integrated valuation of ecosystem services help understanding and steering agroecological transitions?

Directory of Open Access Journals (Sweden)

Nicolas Dendoncker

2018-03-01

Full Text Available Agroecology has been proposed as a promising concept to foster the resilience and sustainability of agroecosystems and rural territories. Agroecological practices are based on optimizing ecosystem services (ES at the landscape, farm, and parcel scales. Recent progress in research on designing agroecological transitions highlights the necessity for coconstructed processes that draw on various sources of knowledge based on shared concepts. But despite the sense of urgency linked to agroecological transitions, feedbacks from real-world implementation remain patchy. The ability of integrated and participatory ES assessments to support this transition remains largely underexplored, although their potential to enhance learning processes and to build a shared territorial perspective is widely recognized. The overarching question that will be asked in this paper is thus: what is the potential of the ES framework to support the understanding and steering of agroecological transitions? We argue that conducting collaborative and integrated assessments of ES bundles can (i increase our understanding of the ecological and social drivers that support a transition toward agroecological systems, and (ii help design agroecological systems based on ES delivery and effectively accompany transition management based on shared knowledge, codesigned future objectives, and actual on-the-ground implementation. In this paper, we discuss this question and propose a four-step integrated ES assessment framework specifically targeted at understanding and steering agricultural transitions that is generic enough to be applied in different contexts.

The utilization of induction generators working with PATs (pumps working as turbines) in electric energy generation; A utilizacao de geradores de inducao acionados por BFTs (bombas funcionando como turbinas) na geracao de energia eletrica

Energy Technology Data Exchange (ETDEWEB)

Viana, Augusto Nelson Carvalho; Rezek, Angelo Jose Junqueira; Medeiros, Daniel de Macedo [Universidade Federal de Itajuba (UNIFEI), MG (Brazil). Programa de Pos-graduacao em Engenharia da Energia], e-mail: augusto@unifei.edu.br, e-mail: rezek@iee.efei.br, e-mail: macedo@unifei.edu.br

2004-07-01

The utilization of the Pumps working as Turbines (PATs) in micro hydro-energy resources to replace the conventional turbines as Pelton, Francis and Propeller have been used in countries as USA, Germany and France. In the mean time, in Brazil this practice and the utilization of induction generators working with PATs is still in the scope of the laboratory experiments. This work, based on experimental results carried on in Laboratory of Hydromechanics for Small Hydro Power Plants (Laboratorio Hidromecanico para Pequenas Centrais Hidroeletricas - LHPCH - UNIFEI), (VIANA, 1987), (VIANA e NOGUEIRA, 1990), propose the utilization of asynchronous generator groups operating with PATs. To show the investment cost decrease in micro hydro power plants (MHPs), is showed the Boa Esperanca MPH example, in which is presented a comparison between the synchronous generator group cost working with a Michell-Banki turbine and a asynchronous generator group operating with a PAT. (author)

Avaliação da estabilidade e da qualidade do patê de presunto, adicionado de globina bovina e de caseinato de sódio, como agente emulsionante Stability and quality of ham paté added of bovine globin and sodium caseinate as emulsifiers

Directory of Open Access Journals (Sweden)

Janaína Guernica Silva

2003-04-01

Full Text Available Este trabalho foi conduzido para avaliar o efeito da incorporação das globinas bovina extraída pelo método da acetona acidificada (GT e pelo da carboximetilcelulose (GCMC e do caseinato de sódio (CA sobre a composição química e as qualidades microbiológica e sensorial do patê de presunto. Foi, ainda, avaliada a estabilidade do produto durante os 45 dias de estocagem sob refrigeração, por meio das determinações de pH e do grau de oxidação lipídica. De acordo com os resultados obtidos, pôde-se verificar que a adição dessas proteínas elevou o teor protéico das amostras analisadas. Além disso, observou-se que apenas a GT provocou uma queda do pH e uma elevação de substâncias reativas ao ácido 2-tiobarbitúrico (thiobarbiuric acid reactive substances - TBARS. Com relação à qualidade microbiológica dos produtos, não foram observadas alterações após a incorporação das proteínas e, pela análise sensorial, foram identificadas diferenças significativas entre as duas formulações de patê avaliadas (PCA e PGCMC.This study evaluated the effect of the use of bovine globin extracted by acidified acetone method (GT, bovine globin extracted by carboxymethyl cellulose method (GCMC and sodium caseinate (CA on the chemical composition and on microbiological and sensorial qualities of the ham paté. Also, the stability of this meat product was studied during the storage for 45 days under refrigeration, on the pH and on the lipid oxidation measurements. An increase of the protein contents was observed in all samples. Moreover, only the incorporation of GT produced a significant decrease of pH and an increasing of thiobarbiuric acid reactive substances (TBARS values during storage. No microbial effects were observed while some significant differences were observed between PCA and PGCMC added patés.

Developing a Natural Gas-Powered Bus Rapid Transit Service: A Case Study

Energy Technology Data Exchange (ETDEWEB)

Mitchell, G.

2015-11-03

The Roaring Fork Transit Authority (RFTA) and its VelociRFTA Bus Rapid Transit (BRT) program are unique in many ways. For example, VelociRFTA was the first rural BRT system in the United States and the operational environment of the VelociRFTA BRT is one of the most severe in the country, with extreme winter temperatures and altitudes close to 8,000 feet. RFTA viewed high altitude operation as the most challenging characteristic when it began considering the use of natural gas. RFTA is the second-largest public transit system in Colorado behind Denver's Regional Transportation District (RTD), and it is one of the largest rural public transit systems in the country. In 2013, RFTA accepted delivery of 22 new compressed natural gas (CNG) buses that went into service after completion of maintenance and refueling facilities earlier that year. This paper examines the lessons learned from RFTA's experience of investigating--and ultimately choosing--CNG for their new BRT program and focuses on the unique environment of RFTA's BRT application; the decision process to include CNG fueling in the project; unforeseen difficulties encountered in the operation of CNG buses; public perception; cost comparison to competing fuels; and considerations for indoor fueling facilities and project funding.

Developing a Natural Gas-Powered Bus Rapid Transit Service. A Case Study

Energy Technology Data Exchange (ETDEWEB)

Mitchell, George [National Renewable Energy Lab. (NREL), Golden, CO (United States)

2015-11-01

The Roaring Fork Transit Authority (RFTA) and its VelociRFTA Bus Rapid Transit (BRT) program are unique in many ways. For example, VelociRFTA was the first rural BRT system in the United States and the operational environment of the VelociRFTA BRT is one of the most severe in the country, with extreme winter temperatures and altitudes close to 8,000 feet. RFTA viewed high altitude operation as the most challenging characteristic when it began considering the use of natural gas. RFTA is the second-largest public transit system in Colorado behind Denver's Regional Transportation District (RTD), and it is one of the largest rural public transit systems in the country. In 2013, RFTA accepted delivery of 22 new compressed natural gas (CNG) buses that went into service after completion of maintenance and refueling facilities earlier that year. This paper examines the lessons learned from RFTA's experience of investigating--and ultimately choosing--CNG for their new BRT program and focuses on the unique environment of RFTA's BRT application; the decision process to include CNG fueling in the project; unforeseen difficulties encountered in the operation of CNG buses; public perception; cost comparison to competing fuels; and considerations for indoor fueling facilities and project funding.

El colapso ambiental en el río Patía, Colombia: variaciones morfológicas y alteraciones en los ecosistemas de manglar

Directory of Open Access Journals (Sweden)

Adriana S Parra

2014-03-01

Full Text Available El delta del Patía ha experimentado grandes variaciones morfológicas en las últimas cuatro décadas debido a presiones antrópicas. El transvase del río Patía al río Sanquianga, debido a la construcción del canal Naranjo en 1973, y la posterior formación del brazo Patianga, han derivado en complejas problemáticas ambientales que se evidencian en la reactivación del lóbulo norte del delta y el abandono de la anterior desembocadura en el lóbulo sur. En este artículo se analizan las principales alteraciones que se presentan en el delta del Patía como producto del desvío del río y las consecuentes variaciones en el aporte fluvial y de sedimentos. Estas alteraciones se reflejan en: (1 cambios drásticos en la línea de costa, con tasas de erosión de hasta 70 m año-1; (2 dulcificación de los estuarios del lóbulo norte del delta, cambio hidrológico que ha ocasionando la migración de la zona alta estuarina (salinidad <1 15 km aguas abajo; y (3 alteraciones en la cobertura vegetal del Parque Nacional Natural Sanquianga, con incrementos en la vegetación de agua dulce de hasta 42%, y disminución en la cobertura de manglar de hasta 31% en un período de 15 años. Las condiciones actuales del delta del Patía son ejemplo de la importancia de las actividades humanas como agentes de cambio dentro de la evolución de los sistemas deltaicos, y revelan la necesidad de profundizar el estudio de este delta para establecer estrategias adecuadas de manejo y conservación.

The Killer Will Remain Free: On Pat Parker and the Poetics of Madness.

Science.gov (United States)

Ali, Kazim

2015-01-01

Poet and scholar Kazim Ali reads Pat Parker's Movement in Black intimately, one poet to another, uncovering the shadow-fact of the lives of most people of color: not only the anger that is somehow sublimated into every part of our lives but also the issue that carrying this feeling around has on our mental health itself-that "anger" and "madness" might have sources in one another. Ali concludes that Parker offers a brutal and clear-eyed and ultimately hopeful assessment of the conditions that were faced at the time, and even now, by communities of color.

'Talking a different language': an exploration of the influence of organizational cultures and working practices on transition from child to adult mental health services.

Science.gov (United States)

McLaren, Susan; Belling, Ruth; Paul, Moli; Ford, Tamsin; Kramer, Tami; Weaver, Tim; Hovish, Kimberly; Islam, Zoebia; White, Sarah; Singh, Swaran P

2013-07-03

Organizational culture is manifest in patterns of behaviour underpinned by beliefs, values, attitudes and assumptions, which can influence working practices. Cultural factors and working practices have been suggested to influence the transition of young people moving from child to adult mental health services. Failure to manage and integrate transitional care effectively can lead to young people losing contact with health and social care systems, resulting in adverse effects on health, well-being and potential. The study aim was to identify the organisational factors which facilitate or impede transition of young people from child and adolescent mental health services (CAMHS) to adult mental health services (AMHS) from the perspective of health professionals and representatives of voluntary organisations. Specific objectives were (i) to explore organizational cultures, structures, processes and resources which influence transition from child to adult mental health services; (ii) identify factors which constitute barriers and facilitators to transition and continuity of care and (iii) make recommendations for service improvements. Within an exploratory, qualitative design thirty four semi-structured interviews were conducted with health and social care professionals working in CAMHS and AMHS in four NHS Mental Health Trusts and four voluntary organizations, in England. A cultural divide appears to exist between CAMHS and AMHS, characterized by different beliefs, attitudes, mutual misperceptions and a lack of understanding of different service structures. This is exacerbated by working practices relating to communication and information transfer which could impact negatively on transition, relational, informational and cross boundary continuity of care. There is also evidence of a cultural shift, with some positive approaches to collaborative working across services and agencies, involving joint posts, parallel working, shared clinics and joint meetings. Cultural

What factors are associated with state performance on provision of transition services to CSHCN?

Science.gov (United States)

Kane, Debra J; Kasehagen, Laurin; Punyko, Judy; Carle, Adam C; Penziner, Andy; Thorson, Sarah

2009-12-01

To examine whether individual, condition-related, and system-related characteristics are associated with state performance (high, medium, low) on the provision of transition services to children with special health care needs (CSHCN). We conducted descriptive, bivariate, and multivariable analyses of 16876 children aged 12 to 17 years by using data from the 2005-2006 National Survey of Children With Special Health Care Needs. Polytomous logistic regression was used to compare the characteristics of CSHCN residing within high-, medium-, and low-performance states, with low-performance states serving as the reference group. Compared with non-Hispanic white CSHCN, Hispanic (adjusted odds ratio [aOR]: 0.25 [95% confidence interval (CI): 0.17-0.37]) and non-Hispanic black (aOR: 0.44 [95% CI: 0.30-0.62]) CSHCN were less likely to reside in a high-performance than in a low-performance state. Compared with CSHCN who had a medical home or adequate insurance coverage, CSHCN who did not have a medical home or adequate insurance coverage were less likely to reside in a high-performance than in a low-performance state (aOR: 0.73 [95% CI: 0.57-0.95]; aOR: 0.73 [95% CI: 0.58-0.93], respectively). Key factors found to be important in a state's performance on provision of transition services to CSHCN were race/ethnicity and having a medical home and adequate insurance coverage. Efforts to support the Maternal and Child Health Bureau's integration of system-level factors in quality-improvement activities, particularly establishing a medical home and attaining and maintaining adequate insurance, are likely to help states improve their performance on provision of transition services.

Enabling Bus Transit Service Quality Co-Monitoring Through Smartphone-Based Platform

DEFF Research Database (Denmark)

Li, Corinna; Zegras, P. Christopher; Zhao, Fang

2017-01-01

’ word, meaning “agencies using public feedback to supplement official monitoring and regulation.”] bus service quality. The pilot project adapted a smartphone-based travel survey system, Future Mobility Sensing, to collect real-time customer feedback and objective operational measurements on specific...... monitoring through a more real-time, customer-centric perspective. The pilot project operated publicly for 3 months on the Silver Line bus rapid transit in Boston, Massachusetts. Seventy-six participants completed the entrance survey; half of them actively participated and completed more than 500...

Mass-spectrometry analysis of histone post-translational modifications in pathology tissue using the PAT-H-MS approach

Directory of Open Access Journals (Sweden)

Roberta Noberini

2016-06-01

Full Text Available Aberrant histone post-translational modifications (hPTMs have been implicated with various pathologies, including cancer, and may represent useful epigenetic biomarkers. The data described here provide a mass spectrometry-based quantitative analysis of hPTMs from formalin-fixed paraffin-embedded (FFPE tissues, from which histones were extracted through the recently developed PAT-H-MS method. First, we analyzed FFPE samples from mouse spleen and liver or human breast cancer up to six years old, together with their corresponding fresh frozen tissue. We then combined the PAT-H-MS approach with a histone-focused version of the super-SILAC strategy-using a mix of histones from four breast cancer cell lines as a spike-in standard- to accurately quantify hPTMs from breast cancer specimens belonging to different subtypes. The data, which are associated with a recent publication (Pathology tissue-quantitative mass spectrometry analysis to profile histone post-translational modification patterns in patient samples (Noberini, 2015 [1], are deposited at the ProteomeXchange Consortium via the PRIDE partner repository with the dataset identifier http://www.ebi.ac.uk/pride/archive/projects/PXD002669.

Project PAT (Pumps Working as Turbines)/IG (Induction Generators): a new concept for generation of electric power through micro scale hydroelectric power plants; Projeto BFT (Bombas Funcionado como Turbinas)/GI (Geradores de Inducao): um novo conceito para geracao de energia eletrica atraves de microcentrais hidreletricas

Energy Technology Data Exchange (ETDEWEB)

Viana, Augusto Nelson Carvalho [Universidade Federal de Itajuba (UNIFEI), Itajuba, MG (Brazil). Inst. de Recursos Naturais. Programa de Pos-graduacao em Engenharia da Energia; Medeiros, Daniel de Macedo; Ricardo, Mateus [Universidade Federal de Itajuba (UNIFEI), Itajuba, MG (Brazil). Inst. de Recursos Naturais], Emails: augusto@unifei.edu.br, macedo@unifei.edu.br, mathidr@yahoo.com.br

2006-07-01

The present work has as objective to present the main bases of 'PAT/IG Project', accomplished in Boa Esperanca Farm (Delfim Moreira - MG), by an accord between Itajuba's Federal University and Mines and Energy Ministry. In a moment that the look for sustainable development is the law in Brazil, low costs and environmental impact alternatives must be prioritized. By this way, the PAT/IG Project continuous the Viana's (1987) works, that developed all Brazilian theoretical bases for using Pumps Working as Turbine (PAT). Besides that, the application of induction motors operating as induction generators will be evaluated, as the velocity control system of the PAT/IG group will be developed. The existing Boa Esperanca Farm's micro power plant will be rebuild ed, to receive a new generating group formed for a PAT and a IG, that will be used as natural sized test workbench of Itajuba's Federal University. At the ending of the project, there will be enough subsidies to prove, in practice, the feasibility presented in laboratorial tests by PAT/IG groups as conventional turbines replacer in micro powerplants. (author)

La Riḥla de Omar Patún: el viaje de peregrinación a la Meca de un musulmán de Ávila a finales del siglo XV (1491–1495 = Omar Patún’s Riḥla : The Journey of the Pilgrimage to Mecca of a Muslim from Ávila at the End of the Fifteenth Century (1491–1495

Directory of Open Access Journals (Sweden)

Xavier Casassas Canals

2015-06-01

Full Text Available En este artículo presentamos la Riḥla de Omar Patún, un relato de viaje y de peregrinación desde Ávila a la Meca realizado por un musulmán castellano a finales del siglo XV. Se trata de un manuscrito inédito hallado en Calanda y conservado en la Biblioteca de Las Cortes de Aragón. Publicamos una selección de textos mostrando las principales etapas del viaje, las circunstancias del mismo y la descripción de algunas de las principales ciudades que visitó Omar Patún. A partir de algunas noticias y referencias, directas e indirectas, a acontecimientos históricos determinamos la fecha exacta del viaje de Omar Patún (1491–1495 y establecemos la cronología de las diferentes etapas y escalas. Ponemos así en conocimiento un documento fundamental para todos aquellos interesados en el estudio de la comunidad musulmana de época mudéjar, que aporta datos novedosos que habrá de tener en cuenta a partir de ahora cuando se hable de la religiosidad de los mudéjares castellanos y de los desplazamientos de éstos a Oriente y en especial a la Meca.This article presents Omar Patún’s Riḥla, an itinerary of the pilgrimage from Ávila to Mecca undertaken by a Castilian Muslim at the end of the fifteenth century. This is an unpublished manuscript found in Calanda and preserved in the Library of the Cortes de Aragón. The selection of texts offered here will identify the most important stages of the journey, its circumstances and the description of some of the cities visited by Patún. Certain news and references in the text to historical events, both direct and indirect, help to date Omar Patún’s journey between 1491–1495, and to establish the chronology of the different stages of the trip and stops on the way. We bring to light an outstanding source for those interested in the Islamic community in Mudejar times as it provides new insights into the religiosity of Castilian Mudejars and their journeys to the Middle

Coordination of IVI and transit signal priority on transit evacuations.

Science.gov (United States)

2011-02-01

During an emergency evacuation, execution time is always critical to the evacuees who are : transit dependent. Transit Signal Priority (TSP) can speed up the transit services by prioritizing : the approaching bus at a signalized intersection. With th...

The impact of transitional care programs on health services utilization in community-dwelling older adults: a systematic review.

Science.gov (United States)

Weeks, Lori E; Macdonald, Marilyn; Martin-Misener, Ruth; Helwig, Melissa; Bishop, Andrea; Iduye, Damilola F; Moody, Elaine

2018-02-01

The objective was to identify and synthesize the best available evidence on the impact of transitional care programs on various forms of health services utilization in community-dwelling older adults. There is growing evidence that transitional care programs can help address important challenges facing health care systems and our increasing older adult population in many countries by reducing unnecessary health service utilization. There is a need for a systematic review of the research evaluating the impact of transitional care programs on hospital and other health service usage. The review included studies on community-dwelling adults age 60 and over with at least one medical diagnosis, and which evaluated the outcomes of transitional care programs on health system utilization of older adults. The outcomes for this review were hospital usage including admissions and readmissions, emergency department usage, primary care/physician usage, nursing home usage, and home health care usage. The review considered experimental and epidemiological study designs including randomized controlled trials, non-randomized controlled trials, quasi-experimental studies, before and after studies, prospective and retrospective cohort studies, and case-control studies. A three-step search was utilized to find published and unpublished studies conducted in any country but reported in English. Six electronic databases were searched from inception of the database to May, 2016. A search for unpublished studies was also conducted. Methodological quality was assessed independently by two reviewers using the Joanna Briggs Institute critical appraisal checklist for systematic reviews and research synthesis. Quantitative data were extracted from included studies independently by the two reviewers using the standardized Joanna Briggs Institute data extraction tools. Due to the methodological heterogeneity of the included studies, a comprehensive meta-analysis for all outcomes was not possible

Contemporary methods of emergency repair works on transit pipelines. Repair works on in-service pipelines

International Nuclear Information System (INIS)

Olma, T.; Winckowski, J.

2007-01-01

The paper presents modern methods and relevant technologies of pipeline failure repairs, basing on TD Williamson technique for hermetic plugging of gas pipelines without interrupting service. Rules for management of emergency situations on the Polish Section of Yamal - Europe Transit Gas Pipeline are being discussed as well. (author)

Transitioning from child and adolescent mental health services with attention-deficit hyperactivity disorder in Ireland: Case note review.

Science.gov (United States)

Tatlow-Golden, Mimi; Gavin, Blanaid; McNamara, Niamh; Singh, Swaran; Ford, Tamsin; Paul, Moli; Cullen, Walter; McNicholas, Fiona

2018-06-01

In a context of international concern about early adult mental health service provision, this study identifies characteristics and service outcomes of young people with attention-deficit hyperactivity disorder (ADHD) reaching the child and adolescent mental health service (CAMHS) transition boundary (TB) in Ireland. The iTRACK study invited all 60 CAMHS teams in Ireland to participate; 8 teams retrospectively identified clinical case files for 62 eligible young people reaching the CAMHS TB in all 4 Health Service Executive Regions. A secondary case note analysis identified characteristics, co-morbidities, referral and service outcomes for iTRACK cases with ADHD (n = 20). Two-thirds of young people with ADHD were on psychotropic medication and half had mental health co-morbidities, yet none was directly transferred to public adult mental health services (AMHS) at the TB. Nearly half were retained in CAMHS, for an average of over a year; most either disengaged from services (40%) and/or actively refused transfer to AMHS (35%) at or after the TB. There was a perception by CAMHS clinicians that adult services did not accept ADHD cases or lacked relevant service/expertise. Despite high rates of medication use and co-morbid mental health difficulties, there appears to be a complete absence of referral to publicly available AMHS for ADHD youth transitioning from CAMHS in Ireland. More understanding of obstacles and optimum service configuration is essential to ensure that care is both available and accessible to young people with ADHD. © 2017 John Wiley & Sons Australia, Ltd.

Staphylococcus aureus, evolución de un viejo patógeno

Directory of Open Access Journals (Sweden)

Ileana Álvarez Lam

2012-12-01

Full Text Available El Staphylococcus aureus está considerado uno de los microorganismos más importantes en la práctica médica diaria. Es capaz de provocar una amplia gama de enfermedades, ya sea por acción directa o mediante la acción de sus toxinas. El tratamiento de estas infecciones se ha convertido en algo extraordinariamente complejo en la época actual como consecuencia de la aparición en la comunidad de cepas de S. aureus, resistentes a la meticillina, que provocan infecciones en pacientes sin factores de riesgo, fundamentalmente niños y adolescentes. En este artículo se hace una revisión, que va desde los cambios en la epidemiología de este patógeno, hasta las implicaciones que para el tratamiento médico presupone este fenómeno.

Transition Services: An Investigation of the Knowledge, Confidence, and Practice of Special Education Teachers in District of Columbia Public Charter High Schools

Science.gov (United States)

Henry, Wallace R., III

2015-01-01

This study was intended to enhance the limited research on the knowledge and confidence of special education teachers in public education regarding transition services and the quality of transition plans they develop. The key variables examined in this study are knowledge, confidence, and the quality of student transition plans. The sample…

Project PAT (Pumps Working as Turbines)/IG (Induction Generators): a new concept for generation of electric power through micro scale hydroelectric power plants; Projeto BFT (Bombas Funcionado como Turbinas)/GI (Geradores de Inducao): um novo conceito para geracao de energia eletrica atraves de microcentrais hidreletricas

Energy Technology Data Exchange (ETDEWEB)

Viana, Augusto Nelson Carvalho [Universidade Federal de Itajuba (UNIFEI), Itajuba, MG (Brazil). Inst. de Recursos Naturais. Programa de Pos-graduacao em Engenharia da Energia; Medeiros, Daniel de Macedo; Ricardo, Mateus [Universidade Federal de Itajuba (UNIFEI), Itajuba, MG (Brazil). Inst. de Recursos Naturais], Emails: augusto@unifei.edu.br, macedo@unifei.edu.br, mathidr@yahoo.com.br

2006-07-01

The present work has as objective to present the main bases of 'PAT/IG Project', accomplished in Boa Esperanca Farm (Delfim Moreira - MG), by an accord between Itajuba's Federal University and Mines and Energy Ministry. In a moment that the look for sustainable development is the law in Brazil, low costs and environmental impact alternatives must be prioritized. By this way, the PAT/IG Project continuous the Viana's (1987) works, that developed all Brazilian theoretical bases for using Pumps Working as Turbine (PAT). Besides that, the application of induction motors operating as induction generators will be evaluated, as the velocity control system of the PAT/IG group will be developed. The existing Boa Esperanca Farm's micro power plant will be rebuild ed, to receive a new generating group formed for a PAT and a IG, that will be used as natural sized test workbench of Itajuba's Federal University. At the ending of the project, there will be enough subsidies to prove, in practice, the feasibility presented in laboratorial tests by PAT/IG groups as conventional turbines replacer in micro powerplants. (author)

Integration of Community Pharmacists in Transition of Care (TOC) Services: Current Trends and Pharmacist Perceptions.

Science.gov (United States)

Zeleznikar, Elizabeth A; Kroehl, Miranda E; Perica, Katharine M; Thompson, Angela M; Trinkley, Katy E

2017-01-01

Barriers exist for patients transitioning from one health-care setting to another, or to home, and health-care systems are falling short of meeting patient needs during this time. Community pharmacist incorporation poses a solution to the current communication breakdown and high rates of medication errors during transitions of care (TOC). The purpose of this study was to determine community pharmacists' involvement in and perceptions of TOC services. Cross-sectional study using electronic surveys nationwide to pharmacists employed by a community pharmacy chain. Of 7236 pharmacists surveyed, 546 (7.5%) responded. Only 33 (6%) pharmacists reported their pharmacy participates in TOC services. Most pharmacists (81.5%) reported receiving discharge medication lists. The most common reported barrier to TOC participation is lack of electronic integration with surrounding hospitals (51.1%). Most pharmacists agreed that (1) it is valuable to receive discharge medication lists (83.3%), (2) receiving discharge medication lists is beneficial for patients' health (89.1%), (3) discharge medication list receipt improves medication safety (88.8%). Most pharmacists reported receiving discharge medication lists and reported discharge medication lists are beneficial, but less than half purposefully used medication lists. To close TOC gaps, health-care providers must collaborate to overcome barriers for successful TOC services.

Regeneration de Pat Barker (1991 : la gestion des maux/mots de la Grande Guerre par l’institution psychiatrique

Directory of Open Access Journals (Sweden)

Isabelle Gérardin

2011-04-01

Full Text Available Cet article se propose d’étudier une œuvre publiée en 1991 par la romancière anglaise Pat Barker : Regeneration. Ce roman, qui a pour toile de fond la Grande Guerre, ne dépeint ni combats ni scènes de la vie des tranchées. Barker préfère représenter toute la dimension agonistique de ce conflit mondial à travers la question de la prise en charge des traumatismes de guerre des soldats par l’institution psychiatrique. Ces traumatismes, ayant diverses manifestations psychosomatiques, témoignent d’une forte tension entre une profonde aversion de l’individu pour l’extrême violence des affrontements et un appel à se conformer à une certaine culture de guerre collective fondée sur un idéal fort de virilité martiale et patriotique. Face à ces traumatismes, ainsi que Pat Barker le met en lumière, la psychiatrie de guerre se révèle souvent fort ambiguë. En effet, l’institution psychiatrique œuvre en continuité avec l’institution militaire, désirant imposer un contrôle sur les âmes autant que sur les corps. Regeneration nous invite donc à lire combien les maux/mots de la Grande Guerre ont eu grand peine à se faire entendre.This article deals with a novel, entitled Regeneration, published in 1991 by the English female author Pat Barker. This novel, although set against the backdrop of World War One, depicts neither battles nor scenes of everyday life in the trenches. Instead, the agonistic dimension of this world conflict is tackled by Pat Barker through the prism of the way the psychiatric institution dealt with war traumas endured by soldiers, traumas of the body and of the mind. These traumas, causing a variety of psychosomatic symptoms, reveal a powerful tension between a deep individual aversion to the extreme violence of combat and an appeal to conform to some collective culture of war rooted in a strong ideal of soldierly and patriotic manliness. Wartime psychiatry, as Barker highlights, often turns out to

Transitioning adolescent and young adults with chronic disease and/or disabilities from paediatric to adult care services - an integrative review.

Science.gov (United States)

Zhou, Huaqiong; Roberts, Pamela; Dhaliwal, Satvinder; Della, Phillip

2016-11-01

This paper aims to provide an updated comprehensive review of the research-based evidence related to the transitions of care process for adolescents and young adults with chronic illness/disabilities since 2010. Transitioning adolescent and young adults with chronic disease and/or disabilities to adult care services is a complex process, which requires coordination and continuity of health care. The quality of the transition process not only impacts on special health care needs of the patients, but also their psychosocial development. Inconsistent evidence was found regarding the process of transitioning adolescent and young adults. An integrative review was conducted using a five-stage process: problem identification, literature search, data evaluation, data analysis and presentation. A search was carried out using the EBSCOhost, Embase, MEDLINE, PsycINFO, and AustHealth, from 2010 to 31 October 2014. The key search terms were (adolescent or young adult) AND (chronic disease or long-term illness/conditions or disability) AND (transition to adult care or continuity of patient care or transfer or transition). A total of 5719 records were initially identified. After applying the inclusion criteria a final 61 studies were included. Six main categories derived from the data synthesis process are Timing of transition; Perceptions of the transition; Preparation for the transition; Patients' outcomes post-transition; Barriers to the transition; and Facilitating factors to the transition. A further 15 subcategories also surfaced. In the last five years, there has been improvement in health outcomes of adolescent and young adults post-transition by applying a structured multidisciplinary transition programme, especially for patients with cystic fibrosis and diabetes. However, overall patients' outcomes after being transited to adult health care services, if recorded, have remained poor both physically and psychosocially. An accurate tracking mechanism needs to be

The Importance of Role Modeling in Mentoring Women: Lessons from Pat Summitt Legacy

Directory of Open Access Journals (Sweden)

Picariello Manuela

2016-10-01

Full Text Available The role of mentoring for women in sports industry has gathered attention among researchers in the past years (Bower, 2009; Bower, & Hums 2009, 2014; Weaver, & Chelladurai, 1999, 2002. Since few women are in leadership positions (Acosta, & Carpenter, 2014, cross-gender mentoring relationships are more likely to happen (Hopkins et al., 2008. However, according to Kram (1985, cross-gender mentoring relationships are more complex in terms of individual development and quality of the developmental relationship. In particular, role modeling function is limited (Kram, 1985. Therefore, the purpose of this study was to examine the functions of the same gender mentoring relationships looking at coach Pat Summitt, the winningest coach in NCAA Division I basketball history and a woman in leadership position (Becker & Wrisberg, 2008. Due to the exploratory nature of the study and the huge impact of Pat Summitt on sport (Janssen, & Dale, 2002, De Marco, & Mccullick, 1997, a single case study design to analyze her relationships from the staff and players’ perspectives was utilized as the method for data collection. This study collected data published on American news sites located using Internet search engines Google News (http://www.google.com for 7 days. The dataset included content published through national and regional online news media, radio, television and entertainment websites and blogs. Texts were qualitatively reviewed with a content analysis and coded (Patton, 2002. This study identified career and psychosocial functions that were important in developing an effective mentoring relationships. In particular, the psychosocial functions of “role modeling” was identified as the most important for the relationship. In fact a female mentor as a role model can be perceived as a woman that has successfully overcome discriminatory barriers to career advancement.

Transport of amino acids and GABA analogues via the human proton-coupled amino acid transporter, hPAT1

DEFF Research Database (Denmark)

Larsen, Mie; Larsen, Birger Brodin; Frølund, Bente

2008-01-01

The objective of this study was to investigate transepithelial amino acid transport as a function of Caco-2 cell culture time. Furthermore, the objective was to investigate apical uptake characteristics of hPAT1-mediated transport under various experimental conditions. Apical amino acid uptake......, which has been shown to function as a carboxylic acid bioisostere for substrates of the GABA receptor and transport systems....

French gas industry in transition: breach in the public service model

International Nuclear Information System (INIS)

Finon, D.

2001-08-01

France is generally viewed as the European country that most vigorously resists the pressure to liberalize its national gas markets. The moderate reform which has resulted from the transcription of the European gas directive was voted in 2002 after much delay. The main reason is the robustness of the French public service-model which has shaped the gas industry organisation in the same way as most of the network industries. To explain the institutional stability of the French gas industry, this document analyses its institutional trajectory shaped by the public service model and its strong institutional path dependency, marked by the resistance to change. The central hypothesis of the analysis is that, as long as this model demonstrates economic and social efficiency in the development of gas supply in relation to public services obligation and in the control of the import dependence risk in the gas sector, no reform can be brought about by endogenous factors. The analysis of the French gas industry transition consists of four sections. After a survey of its historical development, the author presents its organisation and regulation under the public service model and its performances in terms of social and economic efficiency. In the third section, the minimalist reform for transcribing the European Directive in the French law is presented, in order to identify its potential effects in terms of competition development and public service erosion. Finally, in the fourth section, the industrial policy option to preserve the existence of a French mono-energy company and its consequences in terms of strategic adaptation are discussed. (A.L.B.)

Petroleum and Oil Fuel Lines (Apra Harbor through Antonio B. Won Pat Intl Airport to Tanguisson Power Plant), Guam, 2016, US EPA Region 9

Data.gov (United States)

U.S. Environmental Protection Agency — This is a line feature dataset showing the track of petroleum and oil fuel lines that transport hazardous fluids from Apra Harbor through the Antonio B. Won Pat...

Transition from an asylum seeker–specific health service to mainstream primary care for community-based asylum seekers: a qualitative interview study

OpenAIRE

Genevieve L Fair; Mark F Harris; Mitchell M Smith

2018-01-01

Background and aim: Transition of asylum seekers from special-purpose health services to mainstream primary care is both necessary and difficult. This study explores the issues encountered by asylum seekers undergoing this transition in Sydney, Australia. Methods: Qualitative semistructured interviews were conducted with nine asylum seeker patients and nine staff working in the sector. Results: Asylum seekers faced significant challenges in the transition to mainstream primary care. C...

Prevenção da transmissão de patógenos por manipuladores de alimentos

Directory of Open Access Journals (Sweden)

Mirza de Souza Conceição

2015-03-01

Full Text Available O objetivo desta pesquisa foi investigar as formas de prevenção da transmissão de patógeno por manipuladores de alimentos. Este trabalho utilizou uma abordagem qualitativa, mediante uma pesquisa bibliográfica, utilizando dados secundários oriundos de publicações e resultados de pesquisas específicas sobre o assunto realizando uma síntese explicativa sobre a prevenção da transmissão de patógenos por manipuladores de alimentos. As doenças transmitidas por alimentos é uma preocupação de saúde pública a nível mundial. E dentre agentes mais frequentes causadores de DTA’s estão os microrganismos de origem bacteriana como, a Salmonella spp, Escherichia coli, Staphylococcus aureus, Shigella spp, Bacillus cereus e Clostridium perfringens e destacam-se os alimentos de origem animal. Cabe destacar que a maioria dos manipuladores de alimentos necessita de maiores informações relacionadas à qualidade higiênica sanitária durante a fabricação dos produtos, e uma das maneiras de fornecer alimentos seguros é a realização de programas de educação continuada para esses profissionais. Conclui-se que o treinamento dos manipuladores de alimentos ainda é a melhor forma de contribuir para que estas pessoas se conscientizem sobre a sua responsabilidade e tenham cuidado no processamento do alimento.

Public Transit Stations

Data.gov (United States)

Department of Homeland Security — fixed rail transit stations within the Continental United States, Alaska, Hawaii, the District of Columbia, and Puerto Rico. The modes of transit that are serviced...

From Wireless Sensor Networks to Wireless Body Area Networks: Formal Modeling and Verification on Security Using PAT

Directory of Open Access Journals (Sweden)

Tieming Chen

2016-01-01

Full Text Available Model checking has successfully been applied on verification of security protocols, but the modeling process is always tedious and proficient knowledge of formal method is also needed although the final verification could be automatic depending on specific tools. At the same time, due to the appearance of novel kind of networks, such as wireless sensor networks (WSN and wireless body area networks (WBAN, formal modeling and verification for these domain-specific systems are quite challenging. In this paper, a specific and novel formal modeling and verification method is proposed and implemented using an expandable tool called PAT to do WSN-specific security verification. At first, an abstract modeling data structure for CSP#, which is built in PAT, is developed to support the node mobility related specification for modeling location-based node activity. Then, the traditional Dolev-Yao model is redefined to facilitate modeling of location-specific attack behaviors on security mechanism. A throughout formal verification application on a location-based security protocol in WSN is described in detail to show the usability and effectiveness of the proposed methodology. Furthermore, also a novel location-based authentication security protocol in WBAN can be successfully modeled and verified directly using our method, which is, to the best of our knowledge, the first effort on employing model checking for automatic analysis of authentication protocol for WBAN.

From public to private and back again: sustaining a high service-delivery level during transition of management authority: a Cambodia case study.

Science.gov (United States)

Jacobs, Bart; Thomé, Jean-Marc; Overtoom, Rob; Sam, Sam Oeun; Indermühle, Lorenz; Price, Neil

2010-05-01

Contracting non-governmental organizations (NGOs) has been shown to increase health service delivery output considerably over relatively short time frames in low-income countries, especially when applying performance-related pay as a stimulus. A key concern is how to manage the transition back to government-operated systems while maintaining health service delivery output levels. In this paper we describe and analyse the transition from NGO-managed to government-managed health services over a 3-year period in a health district in Cambodia with a focus on the level of health service delivery. Data are derived from four sources, including cross-sectional surveys and health management and financial information systems. The transition was achieved by focusing on all the building blocks of the health care system and ensuring an acceptable financial remuneration for the staff members of contracted health facilities. The latter was attained through performance subsidies derived from financial commitment by the central government, and revenue from user fees. Performance management had a crucial role in the gradual handover of responsibilities. Not all responsibilities were handed back to government over the case study period-notably the development of performance indicators and targets and the performance monitoring.

The Avahan Transition: Effects of Transition Readiness on Program Institutionalization and Sustained Outcomes.

Directory of Open Access Journals (Sweden)

Sachiko Ozawa

Full Text Available With declines in development assistance for health and growing interest in country ownership, donors are increasingly faced with the task of transitioning health programs to local actors towards a path to sustainability. Yet there is little available guidance on how to measure and evaluate the success of a transition and its subsequent effects. This study assesses the transition of the Avahan HIV/AIDS prevention program in India to investigate how preparations for transition affected continuation of program activities post-transition.Two rounds of two surveys were conducted and supplemented by data from government and Avahan Computerized Management Information Systems (CMIS. Exploratory factor analysis was used to develop two measures: 1 transition readiness pre-transition, and 2 institutionalization (i.e. integration of initial program systems into organizational procedures and behaviors post-transition. A fixed effects model was built to examine changes in key program delivery outcomes over time. An ordinary least square regression was used to assess the relationship between transition readiness and sustainability of service outcomes both directly, and indirectly through institutionalization.Transition readiness data revealed 3 factors (capacity, alignment and communication, on a 15-item scale with adequate internal consistency (alpha 0.73. Institutionalization was modeled as a unidimensional construct, and a 12-item scale demonstrated moderate internal consistency (alpha 0.60. Coverage of key populations and condom distribution were sustained compared to pre-transition levels (p<0.01. Transition readiness, but not institutionalization, predicted sustained outcomes post-transition. Transition readiness did not necessarily lead to institutionalization of key program elements one year after transition.Greater preparedness prior to transition is important to achieve better service delivery outcomes post-transition. This paper illustrates a

Evaluación de patógenos en clones de lulo (Solanum quitoense Lam.

Directory of Open Access Journals (Sweden)

Consuelo Montes Rojas

2010-04-01

Full Text Available En el noroccidente de Popayán, Colombia, se evaluó la presencia de plagas causadas por patógenos en 42 clones de lulo (Solanum quitoense Lam.. Los clones fueron plantados en bolsas plásticas, donde se desarrollaron por 3 semanas antes de ser trasplantados al campo. Se utilizó un diseño de bloques completos al azar con cuatro repeticiones, la parcela útil estuvo conformada por 6 plantas, las cuales se sembraron a ‘tresbolillo’ a 2.5 m entre surcos y 2 m entre plantas. Para determinar el efecto de las plagas en el cultivo, se calculó el porcentaje de incidencia y severidad del ataque. La incidencia se evaluó como porcentaje de plantas afectadas, y la severidad como porcentaje de tejido afectado por el patógeno. Las enfermedades más limitantes para los 42 clones fueron: gota (Phytophthora infestans que provocó una mortalidad de plantas superior a 40%; fusarium (Fusarium oxysporum que se presentó en 12 de los clones evaluados; antracnosis (Colletotrichum sp. que afectó 21 clones, los cuales se clasificaron entre tolerantes y medianamente tolerantes; y mancha clorótica (Cladosporium sp. que afectó 21 clones, clasificados como susceptibles. Los clones PL19, PL24, PL11, PL35 fueron medianamente tolerantes. Se seleccionaron por supervivencia los clones: JY E1 (52.2%, PH E 1 (45.8%, VM E2 (45.8%; por supervivencia y por tolerancia a Fusarium oxysporum los clones PL35, PL11, PL24, PL8, PL19, 120052, 120043, ORE1, AGE1. Los clones SER 7, SER 15, SER 9, SEC 31, SEC 27 presentaron alta mortalidad pero se seleccionaron por ser medianamente tolerantes a gota, tolerantes a antracnosis y medianamente resistentes a nematodos, con buen vigor y producción.

Vīrieša tēls patērētāju priekšstatos: žurnāla "Klubs" 2014. gada reklāmu analīze

OpenAIRE

Blumberga, Lelde

2015-01-01

Bakalaura darba ”Vīriešu tēls patērētāju priekšstatos: žurnāla „Klubs” 2014. gada reklāmu analīze” mērķis ir noskaidrot, kāds vīrieša tēls tiek veidots vīriešu žurnālu reklāmas un tā patērētāja priekšstatos. Darba pētnieciskā problēma paredz, ka vīriešu tēls vīriešu žurnālos tiek pasniegts kā spilgts, veiksmīgs un ietekmīgs, kas var atstāt iespaidu uz patērētāja apziņu. Darbs sastāv no trīs daļām – teorētiskās, metodoloģiskās un empīriskās. Darba teorētiskajā daļā tiks apskatīta teorij...

Zīmola nozīme patērētāju lēmuma pieņemšanā mēbeļu mazumtirdzniecībā.

OpenAIRE

Pētersons, Miks

2013-01-01

Maģistra darba temats ir „Zīmola nozīme patērētāju lēmuma pieņemšanā mēbeļu mazumtirdzniecībā”. Darba mērķis ir teorētiski analizēt un praktiski noskaidrot zīmola nozīmi patērētāja lēmuma pieņemšanā par mēbeļu iegādi. Temats ir aktuāls un darbā apkopotie rezultāti var būt saistoši Latvijas mēbeļu nozares dalībniekiem. 1. nodaļā autors izvērtē patērētāju uzvedību noteicošos faktorus, kā arī zīmola nozīme lēmuma pieņemšanā. 2. nodaļā analizēta mēbeļu ražošanas nozare Latvijā, veikta uzņēm...

PAT: From Western solid dosage forms to Chinese materia medica preparations using NIR-CI.

Science.gov (United States)

Zhou, Luwei; Xu, Manfei; Wu, Zhisheng; Shi, Xinyuan; Qiao, Yanjiang

2016-01-01

Near-infrared chemical imaging (NIR-CI) is an emerging technology that combines traditional near-infrared spectroscopy with chemical imaging. Therefore, NIR-CI can extract spectral information from pharmaceutical products and simultaneously visualize the spatial distribution of chemical components. The rapid and non-destructive features of NIR-CI make it an attractive process analytical technology (PAT) for identifying and monitoring critical control parameters during the pharmaceutical manufacturing process. This review mainly focuses on the pharmaceutical applications of NIR-CI in each unit operation during the manufacturing processes, from the Western solid dosage forms to the Chinese materia medica preparations. Finally, future applications of chemical imaging in the pharmaceutical industry are discussed. Copyright © 2015 John Wiley & Sons, Ltd.

Caracterização fenotípica e molecular de genitores de feijão tipo carioca quanto à resistência a patógenos Phenotypic and molecular characterization of genitors of carioca-type common bean regarding their resistance to pathogens

Directory of Open Access Journals (Sweden)

Carlos Lasaro Pereira de Melo

2008-04-01

Full Text Available O objetivo deste estudo foi a caracterização fenotípica e molecular de 31 genótipos de feijão do tipo carioca, quanto à resistência aos patógenos da antracnose, ferrugem e mancha-angular. Foram realizadas inoculações com 13 patótipos de Colletotrichum lindemuthianum, dois de Uromyces appendiculatus e sete de Pseudocercospora griseola. Na caracterização molecular, foram utilizados cinco marcadores moleculares previamente identificados, ligados a diferentes alelos de resistência aos patógenos. Sete genótipos apresentaram resistência a 12 patótipos de C. lindemuthianum. Nove genótipos apresentaram resistência a cinco patótipos de P. griseola. Dez genótipos foram resistentes aos patótipos de U. appendiculatus. As linhagens VC 2, VC 3 e VC 5, além da Rudá-R (linhagem piramidada com cinco genes que conferem resistência a alguns patótipos de antracnose, ferrugem e mancha-angular, foram as que se destacaram quanto à resistência múltipla aos patógenos acima citados. Foi detectado polimorfismo molecular entre a maioria dos genótipos com a Rudá-R, o que indica a possibilidade de uso dos marcadores moleculares SCARF10, SCARY20, SCARAZ20, SCARH13 e OPX11.The present study aimed at the phenotypic and molecular characterization of 31 genotypes of the carioca-type common bean regarding the resistance to anthracnose, rust and angular leaf spot (ALS pathogens. Thirteen pathotypes of Colletotrichum lindemuthianum, two of Uromyces appendiculatus and seven of Pseudocercospora griseola were inoculated. In the molecular characterization, five molecular markers, identified in advance, and linked to the different alleles of pathogens' resistance, were used. Seven genotypes showed resistance to 12 pathotypes of C. lindemuthianum. Nine genotypes presented resistance to five pathotypes of P. griseola. Ten genotypes were resistant to the pathotypes of U. appendiculatus. The lines VC 2, VC 3 and VC 5, besides Rudá-R (line pyramided with five

Good Modeling Practice for PAT Applications: Propagation of Input Uncertainty and Sensitivity Analysis

DEFF Research Database (Denmark)

Sin, Gürkan; Gernaey, Krist; Eliasson Lantz, Anna

2009-01-01

The uncertainty and sensitivity analysis are evaluated for their usefulness as part of the model-building within Process Analytical Technology applications. A mechanistic model describing a batch cultivation of Streptomyces coelicolor for antibiotic production was used as case study. The input...... compared to the large uncertainty observed in the antibiotic and off-gas CO2 predictions. The output uncertainty was observed to be lower during the exponential growth phase, while higher in the stationary and death phases - meaning the model describes some periods better than others. To understand which...... promising for helping to build reliable mechanistic models and to interpret the model outputs properly. These tools make part of good modeling practice, which can contribute to successful PAT applications for increased process understanding, operation and control purposes. © 2009 American Institute...

Veterans transitioning from isolation to integration: a look at veteran/service dog partnerships.

Science.gov (United States)

Crowe, Terry K; Sánchez, Victoria; Howard, Alyse; Western, Brenna; Barger, Stephanie

2017-08-13

This study explored the dynamics of veteran/service dog partnerships by gathering the perspectives of veterans with a history of post-traumatic stress disorder and/or traumatic brain injury. Exploratory qualitative methods (focus groups and individual interviews) were used to investigate veteran/service dog relationships related to community involvement, family and friend relationships, self-care, work, and leisure. Nine male veterans, Paws, and Stripes program graduates participated. Data were audio recorded and transcribed by two research team members who used qualitative analytic software to manage and code the data. The full research team discussed themes and reached consensus on the themes that emerged from analysis. Five themes emerged about the perceived benefit of veteran/service dog relationship: Secluded but Seeking Society (moving from isolation to reconnection); Opening Opportunities (navigating daily life); Bridging the Gap (facilitating social opportunities); and Reclaiming Life (transforming sense of worth and purpose). An overarching theme, Calming Catalyst, connected the other four themes. Veterans in this study reported that their goal was to reclaim and develop key aspects of their lives and they perceived service dogs as a support in their transition from isolation to reintegration. This study found that service dogs supported the veterans to meet their goal. Implications for rehabilitation There are a significant number of veterans with post-traumatic stress disorder and/or traumatic brain injury who are facing life challenges including self-care, securing work, participating in leisure activities, and integrating into the community. Service dogs are an emerging intervention used to assist veterans with reintegration into civilian life. There is a need for professionals to be aware of potential benefits of service dog/veteran partnerships. Based on our findings, veterans could benefit from being paired with a service dog to facilitate their

Escherichia coli O157:H7- patógeno alimentar emergente / Escherichia coli O157:H7 - emerging food pathogen

Directory of Open Access Journals (Sweden)

Cheila Minéia Daniel de Paula

2014-11-01

Full Text Available Segundo a Organização Mundial da Saúde, cerca de 2,2 milhões de pessoas morrem anualmente em função de doenças hídricas ou alimentares, a maioria dos quais são crianças. Estas doenças são causadas por patógenos já conhecidos, emergentes ou reemergentes, principalmente bactérias. A globalização tem contribuído na disseminação de patógenos de origem alimentar, aumentando o desafio relacionado à identificação da origem desses agentes e à elaboração de regulamentação e fiscalização adequadas. O cenário das Doenças Transmitidas por Alimentos (DTA muda constantemente e a prevalência de determinada doença varia de época para época, assim como os agentes etiológicos destas. Dentre os principais patógenos emergentes em nível mundial, E. coli O157:H7 tem ganhado grande destaque nos últimos 20 anos, devido à severidade de seus surtos. Até pouco tempo, o Brasil era considerado livre desse patógeno, porém a bibliografia científica e registros epidemiológicos demonstram o contrário. Em vista disso, o presente artigo objetiva realizar uma revisão integrativa da literatura, enfocando as características, os métodos de isolamento e detecção e os dados epidemiológicos da E. coli O157:H7 no Brasil e no mundo. =============================================== According to the World Health Organization, about 2.2 million people, most of whom are children, die each year due to water and foodborne illnesses. These illnesses are caused by known, emerging, or reemerging pathogens, mainly bacteria. Globalization has contributed to the spread of foodborne pathogens, increasing the challenge of identifying the origin of these agents and of developing appropriate regulation and monitoring. The scenario of Foodborne Illnesses (FI constantly changes and the prevalence of a particular illnesses as well as its etiological agents, vary from season to season. Among the major emerging pathogens at a global level, E. coli O157:H7

Alaska Community Transit

Science.gov (United States)

Grant Information Human Services Funding 5310 5316 (Repealed) 5317 (Repealed) Alaska Mental Health Trust Department of Transportation & Public Facilities/ Alaska Community Transit Search DOT&PF State of Alaska Photo banner DOT&PF> Program Development > Alaska Community Transit Home About Us

Pre-Service Primary Science Teachers' Understandings of the Effect of Temperature and Pressure on Solid-Liquid Phase Transition of Water

Science.gov (United States)

Yalcin, Fatma Aggul

2012-01-01

The aim of this study was to explore pre-service primary teachers' understandings of the effect of temperature and pressure on the solid-liquid phase transition of water. In the study a survey approach was used, and the sample consisted of one-hundred and three, third year pre-service primary science teachers. As a tool for data collection, a test…

Patērētāju uzvedības pētījums par ēdienu piegādes portālu Hungryhouse.co.uk kā e-komercijas dalībnieku.

OpenAIRE

Dembovska, Gerda

2013-01-01

Darba tēma -patērētāju uzvedības pētījums par ēdienu piegādes portālu Hungryhouse.co.uk kā e-komercijas dalībnieku. Autore apraksta patērētāja uzvedības izpētes un e-komercijas teorētiskos aspektus,analizē uzņēmuma Hungryhouse.co.uk. darbību Lielbritānijā,veic aptauju par Hungryhouse.co.uk.pastāvēšanas iespējām Latvijā. Darba mērķis -pamatojoties uz patērētāju uzvedības un e-komercijas teorētiskām atziņām,kā arī uz iedzīvotāju aptaujas rezultātiem, izpētīt ēdiena piegādes portāla Hungryho...

Health Trajectories of Family Caregivers: Associations With Care Transitions and Adult Day Service Use

Science.gov (United States)

Liu, Yin; Kim, Kyungmin; Zarit, Steven H.

2017-01-01

Objective The study examines family caregivers’ health changes over 1 year on four health dimensions and explores the association of differential health trajectories with adult day service (ADS) use and caregiving transitions. Method The participants were 153 primary caregivers of individuals with dementia (IWDs) who provided information on care situations and their own health at baseline, 6-month, and 12-month interviews. Results Caregivers showed increasing functional limitations and decreasing bodily pain over time, whereas role limitation and general health perception remained stable. Furthermore, caregivers’ trajectories of functional limitation were associated with their extent of ADS use at baseline and their relatives’ placement. Discussion Health is multidimensional; all dimensions of caregiver health do not change in a uniform manner. The findings underscore the importance of the association of caregiving transitions and caregiver health and the potential health benefits of ADS use for family caregivers. PMID:25348275

47 CFR 101.4 - Transition plan.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false Transition plan. 101.4 Section 101.4 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Applications and Licenses General Filing Requirements § 101.4 Transition plan. (a) All systems...

Spin-flip tunneling in quantum dots

Energy Technology Data Exchange (ETDEWEB)

Schreiber, Lars; Braakman, Floris; Meunier, Tristan; Calado, Victor; Vandersypen, Lieven [Kavli Institute of NanoScience, Delft (Netherlands); Wegscheider, Werner [Institute for Experimental and Applied Physics, University of Regensburg (Germany)

2010-07-01

Electron spins in a gate-defined double quantum dot formed in a GaAs/(Al,Ga)As 2DEG are promising candidates for quantum information processing as coherent single spin rotation and spin swap has been demonstrated recently. In this system we investigate the two-electron spin dynamics in the presence of microwaves (5.20 GHz) applied to one side gate. During microwave excitation we observe characteristic photon assisted tunneling (PAT) peaks at the (1,1) to (0,2) charge transition. Some of the PAT peaks are attributed to photon tunneling events between the singlet S(0,2) and the singlet S(1,1) states, a spin-conserving transition. Surprisingly, other PAT peaks stand out by their different external magnetic field dependence. They correspond to tunneling involving a spin-flip, from the (0,2) singlet to a (1,1) triplet. The full spectrum of the observed PAT lines is captured by simulations. This process offers novel possibilities for 2-electron spin manipulation and read-out.

Intensive care survivors' experiences of ward-based care: Meleis' theory of nursing transitions and role development among critical care outreach services.

Science.gov (United States)

Ramsay, Pam; Huby, Guro; Thompson, Andrew; Walsh, Tim

2014-03-01

To explore the psychosocial needs of patients discharged from intensive care, the extent to which they are captured using existing theory on transitions in care and the potential role development of critical care outreach, follow-up and liaison services. Intensive care patients are at an increased risk of adverse events, deterioration or death following ward transfer. Nurse-led critical care outreach, follow-up or liaison services have been adopted internationally to prevent these potentially avoidable sequelae. The need to provide patients with psychosocial support during the transition to ward-based care has also been identified, but the evidence base for role development is currently limited. Twenty participants were invited to discuss their experiences of ward-based care as part of a broader study on recovery following prolonged critical illness. Psychosocial distress was a prominent feature of their accounts, prompting secondary data analysis using Meleis et al.'s mid-range theory on experiencing transitions. Participants described a sense of disconnection in relation to profound debilitation and dependency and were often distressed by a perceived lack of understanding, indifference or insensitivity among ward staff to their basic care needs. Negotiating the transition between dependence and independence was identified as a significant source of distress following ward transfer. Participants varied in the extent to which they were able to express their needs and negotiate recovery within professionally mediated boundaries. These data provide new insights into the putative origins of the psychosocial distress that patients experience following ward transfer. Meleis et al.'s work has resonance in terms of explicating intensive care patients' experiences of psychosocial distress throughout the transition to general ward-based care, such that the future role development of critical care outreach, follow-up and liaison services may be more theoretically informed

Improving the seniors' transition from hospital to the community: a case for intensive geriatric service workers.

Science.gov (United States)

McAiney, Carrie A; Hillier, Loretta M; Paul, Janice; McKinnon Wilson, Jane; Tersigni Phelan, Anna; Wagner, Fred; O'Connor, Sheli

2017-01-01

Limited continuity of care, poor communication between healthcare providers, and ineffective self-management are barriers to recovery as seniors transition back to the community following an Emergency Department (ED) visit or hospitalization. The intensive geriatric service worker (IGSW) role is a new service developed in southern Ontario, Canada to address gaps for seniors transitioning home from acute care to prevent rehospitalization and premature institutionalization through the provision of intensive support and follow-up to ensure adherence to care plans, facilitate communication with care providers, and promote self-management. This study describes the IGSW role and provides preliminary evidence of its impact on clients, caregivers and the broader health system. This mixed methods evaluation included a chart audit of all clients served, tracking of the achievement of goals for IGSW involvement, and interviews with clients and caregivers and other key informants. During the study period, 632 clients were served. Rates of goal achievement ranged from 25%-87% and in cases where achieved, the extent of IGSW involvement mostly exceeded recommendations. IGSWs were credited with improving adherence with treatment recommendations, increasing awareness and use of community services, and improving self-management, which potentially reduced ED visits and hospitalizations and delayed institutionalization. The IGSW role has the potential to improve supports for seniors and facilitate more appropriate use of health system resources, and represents a promising mechanism for improving the integration and coordination of care across health sectors.

Profiling the initial 1st Year cohort of patients utilizing a tertiary hospital-based geriatric mental health-care service using the “Service Evaluation Framework”

Directory of Open Access Journals (Sweden)

Subhash Das

2018-01-01

Full Text Available Background: Increase in life expectancy of Indians will require revamping the health-care infrastructure for the elderly. In India, either there are not too many specialized geriatric mental health services available across the country or those that are available have problems of resources and quality. With this perspective, the Department of Psychiatry, Government Medical College and Hospital, Chandigarh, developed the Geriatric Mental Health Clinic (GMHC for the elderly residing in and around Chandigarh. The aim of the study was to study the initial 1-year cohort and assess their satisfaction levels as well as to see whether their functioning improves with the intervention so provided. Materials and Methods: Using the “service evaluation framework,” the patients and caregivers who attended the GMHC over a period of 1 year were evaluated using tools such as Hindi Mental State Examination (HMSE, Everyday Abilities Scale for India (EASI, Global Assessment of Function (GAF scale, World Health Organization quality of life-BREF (WHO-QoL-BREF-Hindi version, and Patient Satisfaction Scale (PAT-SAT. In addition, sociodemographic and clinical profile data of the service users were compiled. Results: A total of 105 cases formed the cohort under study, wherein 70% had functional psychiatric illness and almost more than half of the cases had comorbid physical illness, hypertension being the most common. GAF score of 45.42 and WHO-QoL-BREF score of 78.7 at the time of follow-up suggested that there was “slight impairment in socio-occupational functioning” and “poor QoL,” respectively. However, GAF and HMSE scores were significantly decreased in those with organicity. Overall service users reported good service-cum-clinician satisfaction scores on PAT-SAT; there was also significant reduction of EASI score from that of baseline, suggesting improvement in functioning. Conclusions: Findings show that the newly started GMHC, even though in its

A Nationwide Survey of Disability Support Personnel regarding Transition and Services for Postsecondary Students with Autism Spectrum Disorder

Science.gov (United States)

Muenke, Raychel C.

2011-01-01

The purpose of this exploratory study was to analyze the perceptions (through survey data) of Disability Support Services (DSS) personnel regarding the transition process for students with Autism Spectrum Disorder (ASD) from secondary to postsecondary institutions. Participants from 408 postsecondary institutions completed the survey with 60.4%…

The sensory acceptability of a tilapia (Oreochromis niloticus mechanically separated meat-based spread Aceitabilidade de patê à base de carne de tilápia (Oreochromis niloticus mecanicamente separada

Directory of Open Access Journals (Sweden)

Daniela De Grandi Castro Freitas

2012-06-01

Full Text Available Mechanically Separated Meat (MSM is an alternative for the diversification of new fish-based products and also as a solution for the use of waste from the filleting industries. Tilapia MSM was used in this study for the formulation of a fish spread aimed at investigating its acceptability by consumers. Two spread formulations were prepared with different types of commercial salt: seasoned salt (A and common salt (B. The consumers (112 evaluated their acceptance with respect to overall impression, spreadability, appearance and flavour acceptability on a 9-point hedonic scale. A microbiological analysis of the Tilapia MSM was also carried out and the chemical composition of the Tilapia MSM-based spread determined. When considering the acceptance of all the consumers, the overall impression, appearance and flavour were significantly (P A carne mecanicamente separada (CMS é uma alternativa para a diversificação de novos produtos à base de pescado e também se mostra como um destino para os resíduos da indústria de filetagem. A carne mecanicamente separada de tilápia foi utilizada, neste estudo, na formulação de patê, com o objetivo de investigar a aceitabilidade desse produto pelos consumidores. Duas formulações de patê foram preparadas, com diferentes tipos de sais comerciais: sal temperado (A e sal comum (B. Consumidores (112 avaliaram a aceitação em relação à impressão global, à espalhabilidade, à aparência e ao sabor em escala hedônica de nove pontos. A análise microbiológica da carne mecanicamente separada de tilápia e a composição química da formulação de patê de tilápia também foram determinadas. Quando a aceitação de todos os consumidores foi considerada, a impressão global, a aparência e o sabor foram significativamente (p < 0,05 inferiores para o patê de tilápia com sal comum (B. No entanto, três diferentes grupos de consumidores foram encontrados a partir da aceitabilidade da impressão global do

Transition: Preschool to Kindergarten

Science.gov (United States)

Arizona Department of Education, 2007

2007-01-01

Transition is movement or change without interruption. It should be a smooth flow from one place or condition to another. While the transition plan for a student receiving special education services is designed to prepare him or her for life after high school, transition can start when a child enters preschool. The second of six distinct stages of…

34 CFR 300.43 - Transition services.

Science.gov (United States)

2010-07-01

..., including postsecondary education, vocational education, integrated employment (including supported...; (2) Is based on the individual child's needs, taking into account the child's strengths, preferences..., acquisition of daily living skills and provision of a functional vocational evaluation. (b) Transition...

Improving parent-child interactions for families of children with developmental disabilities.

Science.gov (United States)

Harrold, M; Lutzker, J R; Campbell, R V; Touchette, P E

1992-06-01

Child Management Training (CMT) involves compliance training with a focus on consistent use of antecedents and consequences. Planned Activities Training (PAT) focuses on teaching parents to plan for and engage in activities with their children. A multiple probe design counterbalancing PAT and CMT showed that PAT and CMT were about equally effective in improving mother-child interactions in four families with children with developmental disabilities. Responses to a social validation questionnaire indicated that parents were satisfied with the services received, and that PAT was the slightly preferred treatment. Prior research demonstrated that PAT enhanced the results of CMT. The practical advantages of PAT over CMT are discussed.

An Ordered Regression Model to Predict Transit Passengers’ Behavioural Intentions

Energy Technology Data Exchange (ETDEWEB)

Oña, J. de; Oña, R. de; Eboli, L.; Forciniti, C.; Mazzulla, G.

2016-07-01

Passengers’ behavioural intentions after experiencing transit services can be viewed as signals that show if a customer continues to utilise a company’s service. Users’ behavioural intentions can depend on a series of aspects that are difficult to measure directly. More recently, transit passengers’ behavioural intentions have been just considered together with the concepts of service quality and customer satisfaction. Due to the characteristics of the ways for evaluating passengers’ behavioural intentions, service quality and customer satisfaction, we retain that this kind of issue could be analysed also by applying ordered regression models. This work aims to propose just an ordered probit model for analysing service quality factors that can influence passengers’ behavioural intentions towards the use of transit services. The case study is the LRT of Seville (Spain), where a survey was conducted in order to collect the opinions of the passengers about the existing transit service, and to have a measure of the aspects that can influence the intentions of the users to continue using the transit service in the future. (Author)

2008 Enterprise Transition Plan (ETP)

National Research Council Canada - National Science Library

England, Gordon

2008-01-01

The Enterprise Transition Plan (ETP) is the Department of Defense's integrated business transformation plan, which incorporates the transition plans of the Military Services, Components and the DoD Enterprise...

Test of a sample container for shipment of small size plutonium samples with PAT-2

International Nuclear Information System (INIS)

Kuhn, E.; Aigner, H.; Deron, S.

1981-11-01

A light-weight container for the air transport of plutonium, to be designated PAT-2, has been developed in the USA and is presently undergoing licensing. The very limited effective space for bearing plutonium required the design of small size sample canisters to meet the needs of international safeguards for the shipment of plutonium samples. The applicability of a small canister for the sampling of small size powder and solution samples has been tested in an intralaboratory experiment. The results of the experiment, based on the concept of pre-weighed samples, show that the tested canister can successfully be used for the sampling of small size PuO 2 -powder samples of homogeneous source material, as well as for dried aliquands of plutonium nitrate solutions. (author)

The role of primary health care services to better meet the needs of Aboriginal Australians transitioning from prison to the community.

Science.gov (United States)

Lloyd, Jane E; Delaney-Thiele, Dea; Abbott, Penny; Baldry, Eileen; McEntyre, Elizabeth; Reath, Jennifer; Indig, Devon; Sherwood, Juanita; Harris, Mark F

2015-07-22

Aboriginal Australians are more likely than other Australians to cycle in and out of prison on remand or by serving multiple short sentences-a form of serial incarceration and institutionalisation. This cycle contributes to the over-representation of Aboriginal Australians in prison and higher rates of recidivism. Our research examined how primary health care can better meet the health care and social support needs of Aboriginal Australians transitioning from prison to the community. Purposive sampling was used to identify 30 interviewees. Twelve interviews were with Aboriginal people who had been in prison; ten were with family members and eight with community service providers who worked with former inmates. Thematic analysis was conducted on the interviewees' description of their experience of services provided to prisoners both during incarceration and on transition to the community. Interviewees believed that effective access to primary health care on release and during transition was positively influenced by providing appropriate healthcare to inmates in custody and by properly planning for their release. Further, interviewees felt that poor communication between health care providers in custody and in the community prior to an inmate's release, contributed to a lack of comprehensive management of chronic conditions. System level barriers to timely communication between in-custody and community providers included inmates being placed on remand which contributed to uncertainty regarding release dates and therefore difficulties planning for release, cycling in and out of prison on short sentences and being released to freedom without access to support services. For Aboriginal former inmates and family members, release from prison was a period of significant emotional stress and commonly involved managing complex needs. To support their transition into the community, Aboriginal former inmates would benefit from immediate access to culturally- responsive

Federal and state benefits for transition age youth.

Science.gov (United States)

Altman, Stephanie; O'Connor, Sarah; Anapolsky, Ellyce; Sexton, Laura

2014-01-01

While all children face challenges as they become adults, children with chronic medical conditions or disabilities face unique barriers in their transition to adulthood. Children, especially those who are low income and have special needs, are eligible for a range of supports including income supports, health care coverage, vocational and educational supports. These supports are critical to sound health because they ensure access to necessary medical services, while also offsetting the social determinants that negatively affect health. Unfortunately, as children transition into adulthood, eligibility for these benefits can change abruptly or even end entirely. If medical providers have a better understanding of five transition key dates, they can positively impact their patients' health by ensuring continuous coverage through the transition to adulthood. The key dates are as follows: (1) transition services for students with an Individualized Education Program (IEP) must begin by age 16 (in some states such as Illinois, these services must be in place by age 14 1/2); (2) at age 18, eligibility for income supports may change; (3) at age 19, eligibility for Medicaid may change; (4) at graduation, eligibility for educational supports will end unless steps are taken to extend those benefits until age 22; and (5) when individuals prepare to enter the workforce, they will become eligible for vocational rehabilitation services. With an understanding of these key transition dates and how to partner with social services and advocacy organizations on behalf of their patients, medical providers can help to ensure that transition-age patients retain the holistic social services and supports they need to protect their health.

Short-term effects of a dung pat on N₂ fixation and total N uptake in a perennial ryegrass/white clover mixture

DEFF Research Database (Denmark)

Jørgensen, F.V.; Jensen, E.S.

1997-01-01

The short-term effects of a simulated cattle dung pat on N-2 fixation and total uptake of N in a perennial ryegrass/white clover mixture was studied in a container experiment using sheep faeces mixed with water to a DM content of 13%. We used a new N-15 cross-labelling technique to determine...

Transitioning a home telehealth project into a sustainable, large-scale service: a qualitative study.

Science.gov (United States)

Wade, Victoria A; Taylor, Alan D; Kidd, Michael R; Carati, Colin

2016-05-16

This study was a component of the Flinders Telehealth in the Home project, which tested adding home telehealth to existing rehabilitation, palliative care and geriatric outreach services. Due to the known difficulty of transitioning telehealth projects services, a qualitative study was conducted to produce a preferred implementation approach for sustainable and large-scale operations, and a process model that offers practical advice for achieving this goal. Initially, semi-structured interviews were conducted with senior clinicians, health service managers and policy makers, and a thematic analysis of the interview transcripts was undertaken to identify the range of options for ongoing operations, plus the factors affecting sustainability. Subsequently, the interviewees and other decision makers attended a deliberative forum in which participants were asked to select a preferred model for future implementation. Finally, all data from the study was synthesised by the researchers to produce a process model. 19 interviews with senior clinicians, managers, and service development staff were conducted, finding strong support for home telehealth but a wide diversity of views on governance, models of clinical care, technical infrastructure operations, and data management. The deliberative forum worked through these options and recommended a collaborative consortium approach for large-scale implementation. The process model proposes that the key factor for large-scale implementation is leadership support, which is enabled by 1) showing solutions to the problems of service demand, budgetary pressure and the relationship between hospital and primary care, 2) demonstrating how home telehealth aligns with health service policies, and 3) achieving clinician acceptance through providing evidence of benefit and developing new models of clinical care. Two key actions to enable change were marketing telehealth to patients, clinicians and policy-makers, and building a community of

[The Patient Rights Act (PatRG)--part 1: legislative procedure, treatment contract, contracting parties and their obligations to cooperate and inform].

Science.gov (United States)

Parzeller, Markus; Zedler, Barbara

2013-01-01

The article deals with the new regulations in the German Civil Code (BGB) which came into effect in Germany on 26 Feb 2013 as the Patient Rights Act (PatRG). In Part I, the legislative procedure, the treatment contract and the contracting parties (Section 630a Civil Code), the applicable regulations (Section 630b Civil Code) and the obligations to cooperate and inform (Section 630c Civil Code) are discussed and critically analysed.

Simultaneous enrichment of cysteine-containing peptides and phosphopeptides using a cysteine-specific phosphonate adaptable tag (CysPAT) in combination with titanium dioxide (TiO2) chromatography

DEFF Research Database (Denmark)

Huang, Honggang; Pedersen, Martin Haar; Ibañez-Vea, Maria

2016-01-01

to selectively label cysteine-containing peptides (Cys peptides) followed by their enrichment with titanium dioxide (TiO2) and subsequent mass spectrometric analysis. The CysPAT strategy was developed using a synthetic peptide, a standard protein and subsequently the strategy was applied to protein lysates from...

Real-time subway information for improving transit ridership.

Science.gov (United States)

2016-08-01

In recent years, the standardization of transit schedule information has yielded a dramatic increase in the accessibility of computerized transit schedules and given rise to real-time service schedules. Two such real-time service schedules are the Ge...

Effects of tunnel and station size on the costs and service of subway transit systems

Science.gov (United States)

Dayman, B., Jr.

1979-01-01

The feasibility of less spacious, less costly underground rail mass transit system designs is studied. The major cost saving expected from alternative tunnel designs results from using precast concrete segment liners in place of steel. The saying expected for a two-foot decrease in the diameter of twin, single track tunnels is about two million dollars per route mile from 13 million dollars for precast concrete segment liners (a saving of about 16%). The cost per route-mile of a double track tunnel appears to be 15 to 25% higher than for the twin, single track tunnels. The effective cost saving expected from stations with four-car train capability instead of the usual eight-car trains is nearly 25% or seven million dollars per route mile. The saving in station costs can be obtained while improving service to the user (lower transit time and less waiting for trains) up to a capacity of 36,000 riders per hour in each direction.

Evaluación de patógenos en clones de lulo (Solanum quitoense Lam.

Directory of Open Access Journals (Sweden)

Montes Rojas Consuelo

2010-06-01

Full Text Available

En el noroccidente de Popayán, Colombia, se evaluó la presencia de plagas causadas por patógenos en 42 clones de lulo (Solanum quitoense Lam.. Los clones fueron plantados en bolsas plásticas, donde se desarrollaron por 3 semanas antes de ser trasplantados al campo. Se utilizó un diseño de bloques completos al azar con cuatro repeticiones, la parcela útil estuvo conformada por 6 plantas, las cuales se sembraron a 'tresbolillo' a 2.5 m entre surcos y 2 m entre plantas. Para determinar el efecto de las plagas en el cultivo, se calculó el porcentaje de incidencia y severidad del ataque. La incidencia se evaluó como porcentaje de plantas afectadas, y la severidad como porcentaje de tejido afectado por el patógeno. Las enfermedades más limitantes para los 42 clones fueron: gota (Phytophthora infestans que provocó una mortalidad de plantas superior a 40%; fusarium (Fusarium oxysporum que se presentó en 12 de los clones evaluados; antracnosis (Colletotrichum sp. que afectó 21 clones, los cuales se clasificaron entre tolerantes y medianamente tolerantes; y mancha clorótica (Cladosporium sp. que afectó 21 clones, clasificados como susceptibles. Los clones PL19, PL24, PL11, PL35 fueron medianamente tolerantes. Se seleccionaron por supervivencia los clones: JY E1 (52.2%, PH E 1 (45.8%, VM E2 (45.8%; por supervivencia y por tolerancia a Fusarium oxysporum los clones PL35, PL11, PL24, PL8, PL19, 120052, 120043, ORE1, AGE1. Los clones SER 7, SER 15, SER 9, SEC 31, SEC 27 presentaron alta mortalidad pero se seleccionaron por ser medianamente tolerantes a gota, tolerantes a antracnosis y medianamente resistentes a nematodos, con buen vigor y producción.

Implementation of an advanced hybrid MPC-PID control system using PAT tools into a direct compaction continuous pharmaceutical tablet manufacturing pilot plant.

Science.gov (United States)

Singh, Ravendra; Sahay, Abhishek; Karry, Krizia M; Muzzio, Fernando; Ierapetritou, Marianthi; Ramachandran, Rohit

2014-10-01

It is desirable for a pharmaceutical final dosage form to be manufactured through a quality by design (QbD)-based approach rather than a quality by testing (QbT) approach. An automatic feedback control system coupled with PAT tools that is part of the QbD paradigm shift, has the potential to ensure that the pre-defined end product quality attributes are met in a time and cost efficient manner. In this work, an advanced hybrid MPC-PID control architecture coupled with real time inline/online monitoring tools and principal components analysis (PCA) based additional supervisory control layer has been proposed for a continuous direct compaction tablet manufacturing process. The advantages of both MPC and PID have been utilized in a hybrid scheme. The control hardware and software integration and implementation of the control system has been demonstrated using feeders and blending unit operation of a continuous tablet manufacturing pilot plant and an NIR based PAT tool. The advanced hybrid MPC-PID control scheme leads to enhanced control loop performance of the critical quality attributes in comparison to a regulatory (e.g. PID) control scheme indicating its potential to improve pharmaceutical product quality. Copyright © 2014 Elsevier B.V. All rights reserved.

CaMKII-MEDIATED PHOSPHORYLATION OF THE BOMBYX MORI LIPID STORAGE DROPLET PROTEIN-1 (BmLsd1), AN INSECT PAT FAMILY PROTEIN, IS ESSENTIAL FOR SILKMOTH SEX PHEROMONE BIOSYNTHESIS

Science.gov (United States)

The structurally-related members of the PAT family of proteins, which are so name based on similarity amongst perilipin, adipophilin/adipocyte differentiation-related protein (ADRP), and tail-interacting protein of 47 kilodaltons (TIP47), are cytoplasmic lipid droplet (LD)-associated proteins charac...

Transitioning a Large Scale HIV/AIDS Prevention Program to Local Stakeholders: Findings from the Avahan Transition Evaluation.

Directory of Open Access Journals (Sweden)

Sara Bennett

Full Text Available Between 2009-2013 the Bill and Melinda Gates Foundation transitioned its HIV/AIDS prevention initiative in India from being a stand-alone program outside of government, to being fully government funded and implemented. We present an independent prospective evaluation of the transition.The evaluation drew upon (1 a structured survey of transition readiness in a sample of 80 targeted HIV prevention programs prior to transition; (2 a structured survey assessing institutionalization of program features in a sample of 70 targeted intervention (TI programs, one year post-transition; and (3 case studies of 15 TI programs.Transition was conducted in 3 rounds. While the 2009 transition round was problematic, subsequent rounds were implemented more smoothly. In the 2011 and 2012 transition rounds, Avahan programs were well prepared for transition with the large majority of TI program staff trained for transition, high alignment with government clinical, financial and managerial norms, and strong government commitment to the program. One year post transition there were significant program changes, but these were largely perceived positively. Notable negative changes were: limited flexibility in program management, delays in funding, commodity stock outs, and community member perceptions of a narrowing in program focus. Service coverage outcomes were sustained at least six months post-transition.The study suggests that significant investments in transition preparation contributed to a smooth transition and sustained service coverage. Notwithstanding, there were substantive program changes post-transition. Five key lessons for transition design and implementation are identified.

Rethinking Healthcare Transitions and Policies: Changing and Expanding Roles in Transitional Care

Science.gov (United States)

Moreño, Patricienn K.

2014-01-01

The breakdown of care transitions between various healthcare facilities, providers, and services is a major issue in healthcare, and accounts for over US$15 billion in healthcare expenditures annually. The transition between inpatient care and home care is a very delicate period where, too often, chronically ill patients get worse and wind up back…

Can the Medical Home eliminate racial and ethnic disparities for transition services among Youth with Special Health Care Needs?

Science.gov (United States)

Richmond, Nicole E; Tran, Tri; Berry, Susan

2012-05-01

The Medical Home (MH) is shown to improve health outcomes for Youth with Special Health Care Needs (YSHCN). Some MH services involve Transition from pediatric to adult providers to ensure YSHCN have continuous care. Studies indicate racial/ethnic disparities for Transition, whereas the MH is shown to reduce health disparities. This study aims to (1) Determine the Transition rate for YSHCN with a MH (MH Transition) nationally, and by race/ethnicity (2) Identify which characteristics are associated with MH Transition (3) Determine if racial/ethnic disparities exist after controlling for associated characteristics, and (4) Identify which characteristics are uniquely associated with each race/ethnic group. National survey data were used. YSCHN with a MH were grouped as receiving Transition or not. Characteristics included race, ethnicity (Non-Hispanic (NH), Hispanic), sex, health condition effect, five special health care need categories, education, poverty, adequate insurance, and urban/rural residence. Frequencies, chi-square, and logistic regression were used to calculate rates and define associations. Alpha was set to 0.05. About 57.0% of YSHCN received MH Transition. Rates by race/ethnicity were 59.0, 45.5, 60.2, 41.9, and 44.6% for NH-White, NH-Black, NH-Multiple race, NH-Other, and Hispanic YSHCN, respectively. Disparities remained between NH-White and NH-Black YSHCN. All characteristics except urban/rural status were associated. Adequate insurance was associated for all race/ethnic groups, except NH-Black YSHCN. Almost 57.0% of YSHCN received MH Transition. Disparities remained. Rates and associated characteristics differed by race/ethnic group. Culturally tailored interventions incorporating universal factors to improve MH Transition outcomes are warranted.

A Process Analytical Technology (PAT) approach to control a new API manufacturing process: development, validation and implementation.

Science.gov (United States)

Schaefer, Cédric; Clicq, David; Lecomte, Clémence; Merschaert, Alain; Norrant, Edith; Fotiadu, Frédéric

2014-03-01

Pharmaceutical companies are progressively adopting and introducing Process Analytical Technology (PAT) and Quality-by-Design (QbD) concepts promoted by the regulatory agencies, aiming the building of the quality directly into the product by combining thorough scientific understanding and quality risk management. An analytical method based on near infrared (NIR) spectroscopy was developed as a PAT tool to control on-line an API (active pharmaceutical ingredient) manufacturing crystallization step during which the API and residual solvent contents need to be precisely determined to reach the predefined seeding point. An original methodology based on the QbD principles was designed to conduct the development and validation of the NIR method and to ensure that it is fitted for its intended use. On this basis, Partial least squares (PLS) models were developed and optimized using chemometrics methods. The method was fully validated according to the ICH Q2(R1) guideline and using the accuracy profile approach. The dosing ranges were evaluated to 9.0-12.0% w/w for the API and 0.18-1.50% w/w for the residual methanol. As by nature the variability of the sampling method and the reference method are included in the variability obtained for the NIR method during the validation phase, a real-time process monitoring exercise was performed to prove its fit for purpose. The implementation of this in-process control (IPC) method on the industrial plant from the launch of the new API synthesis process will enable automatic control of the final crystallization step in order to ensure a predefined quality level of the API. In addition, several valuable benefits are expected including reduction of the process time, suppression of a rather difficult sampling and tedious off-line analyses. © 2013 Published by Elsevier B.V.

Strategic framework for education and training in Quality by Design (QbD) and process analytical technology (PAT).

Science.gov (United States)

de Matas, Marcel; De Beer, Thomas; Folestad, Staffan; Ketolainen, Jarkko; Lindén, Hans; Lopes, João Almeida; Oostra, Wim; Weimer, Marco; Öhrngren, Per; Rantanen, Jukka

2016-07-30

The regulatory and technical landscape of the pharmaceutical field is rapidly evolving from one focused predominantly on development of small molecules, using well established manufacturing technologies towards an environment in which biologicals and complex modalities are being developed using advanced science and technology coupled with the application of modern Quality by Design (QbD) principles. In order that Europe keeps pace with these changes and sustains its position as major player in the development and commercialization of medicines, it is essential that measures are put in place to maintain a highly skilled workforce. A number of challenges however exist to equipping academic, industrial and health agency staff with the requisite knowledge, skills and experience to develop the next generation of medicines. In this regard, the EUFEPS QbD and PAT Sciences Network has proposed a structured framework for education, training and continued professional development, which comprises a number of pillars covering the fundamental principles of modern pharmaceutical development including the underpinning aspects of science, engineering and technology innovation. The framework is not prescriptive and is not aimed at describing specific course content in detail. It should however be used as a point of reference for those institutions delivering pharmaceutical based educational courses, to ensure that the necessary skills, knowledge and experience for successful pharmaceutical development are maintained. A positive start has been made and a number of examples of formal higher education courses and short training programs containing elements of this framework have been described. The ultimate vision for this framework however, is to see widespread adoption and proliferation of this curriculum with it forming the backbone of QbD and PAT science based skills development. Copyright © 2016 Elsevier B.V. All rights reserved.

Ocorrência de patógenos em cultivos de melancia e abóbora no sertão da Paraíba

Directory of Open Access Journals (Sweden)

M. G. F. O. Soares

2016-01-01

Full Text Available Por constituírem uma importante fonte de alimento, plantações de melancia e abóbora são comumente cultivadas no sertão paraibano, porém pouco se sabe sobre a ocorrência de patógenos causadores de doenças, os quais limitam a sua produtividade e renda aos produtores. Visando obter informações sobre a ocorrência dos patógenos virais e fúngicos em cultivos de abóbora e melancia situados em municípios produtores no sertão da Paraíba, amostras coletadas com sintomas de mosaico e deformação foliar, típicos de doenças virais foram analisadas pela técnica sorológica “enzime linked immuno sorbentassay” (Elisa indireto para Papaya ring spot virus, type watermelon (PRSV-W, Watermelon mosaic virus (WMV, Zucchini yellow mosaic virus (ZYMV e Cucumber mosaic virus (CMV. O teste de dupla difusão em Agar foi utilizado para verificar a presença de Squash mosaic virus (SqMV. Em contrapartida, amostras coletadas com sintomas de doenças fúngicas foram analisadas pelo isolamento do patógeno e visualização de suas características morfológicas em microscópio óptico. Em abóbora, houve prevalência dos vírus ZYMV e PRSV-W em infecções simples e mistas, e maior incidência dos fungos Cladosporium spp., e Alternaria spp. Em melancia detectou-se infecção simples e mistas das espécies PRSV-W, WMV e ZYMV, e maior freqüência de Fusarium spp. e Alternaria spp.. Não foram detectados os vírus CMV e SqMV. Os resultados obtidos revelam a ocorrência de vários patógenos fúngicos e viróticos em cultivos de abóbora e melancia situados no sertão da Paraíba e ressaltam a importância da utilização de estratégias de manejo que reduzem os danos ocasionados por esses patógenos.Occurrence of pathogens in watermelon and pumpkin crops in the State of ParaibaAbstract: By constitute an important food source, watermelon and pumpkin plantations are commonly grown on Paraíba backlands, but little is known about the occurrence of disease

Assessing the implementation of a bedside service handoff on an academic hospitalist service.

Science.gov (United States)

Wray, Charlie M; Arora, Vineet M; Hedeker, Donald; Meltzer, David O

2018-06-01

Inpatient service handoffs are a vulnerable transition during a patients' hospitalization. We hypothesized that performing the service handoff at the patients' bedside may be one mechanism to more efficiently transfer patient information between physicians, while further integrating the patient into their hospital care. We performed a 6-month prospective study of performing a bedside handoff (BHO) at the service transition on a non-teaching hospitalist service. On a weekly basis, transitioning hospitalists co-rounded at patient's bedsides. Post-handoff surveys assessed for completeness of handoff, communication, missed information, and adverse events. A control group who performed the handoff via email, phone or face-to-face was also surveyed. Chi-square and item-response theory (IRT) analysis assessed for differences between BHO and control groups. Narrative responses were elicited to qualitatively describe the BHO. In total, 21/31 (67%) scheduled BHOs were performed. On average, 4 out of 6 eligible patients experienced a BHO, with a total of 90 patients experiencing a BHO. Of those asked to perform the BHO, 52% stated the service transition took 31-60 min compared to 24% in the control group. Controlling for the nesting of observations within physicians, IRT analysis found that BHO respondents had statistically significant greater odds of: reporting increased patient awareness of the service handoff, more certainty in the plan for each patient, less discovery of missed information, and less time needed to learn about the patient on the first day compared to control methods. Narrative responses described a more patient-centered handoff with improved communication that was time-consuming and often logistically difficult to implement. Despite its time-intensive nature, performing the service handoff at the patient's bedside may lead to a more complete and efficient service transition. Published by Elsevier Inc.

Transicion de la Escuela a la Vida Adulta Manual de Informacion para la Provision de Servicios de Transicion a los Jovenes con Impedimentos (Transition from School to Adult Life. Manual of Information for the Provision of Transitional Services for Youth with Disabilities).

Science.gov (United States)

Puerto Rico State Dept. of Education, Hato Rey. Office of Special Education.

This manual has been prepared to orient school personnel in the development of programs for the transition of students with disabilities from school to adult life so that they can fulfill their responsibilities in planning and providing services. The laws under which such services are required are reviewed, and the services and planning are…

Business models for Serious Games developers - transition from a product centric to a service centric approach

DEFF Research Database (Denmark)

Hauge, Jannicke Baalsrud; Wiesner, Stefan; Sanchez, Rosa Garcia

2014-01-01

In the context of the serious games industry, up to now the most commonly used business models (BM) among developers representing small and medium enterprises (SMEs) consists in offering an individual product to the customer, based on tailored one-of a kind production. Such production has high...... application fields of SG, before it presents two examples of a successful transition towards a service oriented BM within the same fields Based on this, it finally discusses the opportunities and the threats of using such BMs for SG developers....

Pediatric Renal Transplantation: Focus on Current Transition Care and Proposal of the "RISE to Transition" Protocol.

Science.gov (United States)

Raina, Rupesh; Wang, Joseph; Krishnappa, Vinod; Ferris, Maria

2018-01-16

The transition from pediatric to adult medical services is an important time in the life of an adolescent or young adult with a renal transplant. Failure of proper transition can lead to medical non-adherence and subsequent loss of graft and/or return to dialysis. The aim of this study was to conduct a systematic review and survey to assess the challenges and existing practices in transition of renal transplant recipient children to adult services, and to develop a transition protocol. We conducted a literature review and performed a survey of pediatric nephrologists across the United States to examine the current state of transition care. A structured transition protocol was developed based on these results. Our literature review revealed that a transition program has a positive impact on decline in renal function and acute rejection episodes, and may improve long-term graft outcomes in pediatric kidney transplant patients. With a response rate of 40% (60/150) from nephrologists in 56% (49/87) of centers, our survey shows inconsistent use of validated tools despite their availability, inefficient communication between teams, and lack of use of dedicated clinics. To address these issues, we developed the "RISE to Transition" protocol, which relies on 4 competency areas: Recognition, Insight, Self-reliance, and Establishment of healthy habits. The transition program decreases acute graft rejection episodes, and the main challenges in transition care are the communication gap between health care providers and inconsistent use of transition tools. Our RISE to transition protocol incorporates transition tools, defines personnel, and aims to improve communication between teams.

Transition: New Challenge for Special Education.

Science.gov (United States)

Dildy, Dennis R.

Special education students who graduate or age-out of school are often not successful in making the transition from school to work. Transition services in Texas are grounded in federal civil rights legislation and a Texas Senate concurrent resolution which calls for preparing and supporting the successful transition of handicapped students to the…

Transit experience with hydrogen fueled hybrid electric buses

International Nuclear Information System (INIS)

Scott, P.B.; Mazaika, D.M.; Levin, J.; Edwards, T.

2006-01-01

Both AC Transit and SunLine Transit operate hybrid electric hydrogen fueled buses in their transit service. ACT presently operates three fuel cell buses in daily revenue service, and SunLine operates a fuel cell bus and a HHICE (Hybrid Hydrogen Internal Combustion Engine) bus. All these buses use similar electric drive train and electric accessories, although the detailed design differs notably between the fuel cell and the hybrid ICE buses. The fuel cell buses use a 120kW UTC fuel cell and a Van Hool Chassis, whereas the HHICE bus uses a turbocharged Ford engine which is capable of 140kW generator output in a New Flyer Chassis. The HHICE bus was the first in service, and has been subjected to both winter testing in Manitoba, Canada and summer testing in the Palm Springs, CA region. The winter testing included passenger sampling using questionnaires to ascertain passenger response. The fuel cell buses were introduced to service at the start of 2006. All five buses are in daily revenue service use. The paper will describe the buses and the experience of the transit properties in operating the buses. (author)

FTA real-time transit information assessment : white paper on literature review of real-time transit information systems.

Science.gov (United States)

Real-time transit information systems are key technology applications within the transit industry designed to provide better customer service by disseminating timely and accurate information. Riders use this information to make various decisions abou...

An Overview of Quality Programs that Support Transition-Aged Youth

Directory of Open Access Journals (Sweden)

Christopher M. Kalinyak

2016-12-01

Full Text Available This article provides a concise overview of several programs that deliver services to transition-aged youth, ages 14–29. Included are family support, the Assisting Unaccompanied Children and Youth program, the Substance Abuse and Mental Health Services Administration services, the wraparound approach, intensive home-based treatment, multisystemic therapy, foster care, independent living, mentoring, the Steps to Success program, the Jump on Board for Success program, the Options program, the Positive Action program, the Transition to Success model, and the Transition to Independence Program. Primary focus is placed upon the usefulness of each of the programs in facilitating successful outcomes for transition-aged youth.

Integrating a health information exchange into a community pharmacy transitions of care service.

Science.gov (United States)

Fanizza, Frank A; Ruisinger, Janelle F; Prohaska, Emily S; Melton, Brittany L

2018-04-03

To describe the incorporation of a state health information exchange (HIE) into a community pharmacy transitions of care (TOC) service and to assess its impact on 30-day readmission rates. Three suburban community pharmacies in Olathe, Kansas. Balls Food Stores is a grocery store chain which operates 21 supermarket community pharmacies in the Kansas City metropolitan area. Balls Food Stores launched a pharmacist-led self-referral TOC study in which a state HIE was utilized to collect discharge information from patients' electronic medical records (EMRs) to facilitate TOC comprehensive medication reviews (CMRs). Descriptive statistics were used to assess types and outcomes of identified drug therapy problems and the ability to access Kansas Health Information Network EMRs. A chi-square test was used to assess 30-day readmissions between patients who accepted and declined the service. Forty patients were identified for inclusion and 18 elected to participate in the service. The majority of participants were white females with a median age of 64.5 years. Out of 40 study patients, 85% had an EMR available; 12.5% of patients had a medication list included in their EMR hospitalization documentation. Participants who underwent the service had a statistically significantly lower rate of overall 30-day hospital readmission than those who declined (11.1% vs 36.4%, P = 0.032). Among the 18 TOC CMRs performed, 90 drug therapy problems were identified and 77 were resolved in collaboration with a patient, caregiver, or physician. Incorporation of a state HIE into a community pharmacist-led TOC service is a novel strategy for collecting patient data. During the study, no TOC participants were readmitted within 30 days. However, pharmacists found HIE data alone was insufficient to perform TOC CMRs for the majority of participants. In order to expand state HIE utilization, more health systems will need to upload a minimum standard data set to help facilitate care. Copyright © 2018

BC Transit Fuel Cell Bus Project: Evaluation Results Report

Energy Technology Data Exchange (ETDEWEB)

Eudy, L. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Post, M. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

2014-02-01

This report evaluates a fuel cell electric bus demonstration led by British Columbia Transit (BC Transit) in Whistler, Canada. BC Transit is collaborating with the California Air Resources Board and the U.S. Department of Energy's National Renewable Energy Laboratory to evaluate the buses in revenue service. This evaluation report covers two years of revenue service data on the buses from April 2011 through March 2013.

Final report : Calgary Transit customer satisfaction survey 2005

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-02-15

This survey was conducted to measure the customer satisfaction of Calgary Transit users and gather information for further service improvements. The survey was conducted by telephone with a total of 500 current customers, and results were compared with previous surveys. The average number of trips per week among regular customers was 7.6, the lowest over the past 6 years. Twenty-six per cent of customers used the service more frequently due to higher gas prices, lack of a vehicle and the higher frequency of services. While most customers used buses, there was an increase in train usage in 2005, which was attributed to an increase in service frequency. Customers typically reported travelling during rush hour periods. Transit customers assigned a global score of 8.2 for service quality satisfaction and loyalty, which was consistent with previous scores. Seventy-two per cent of customers rated service quality as excellent or good. Approximately 1 in 5 customers perceived Calgary Transit to have improved over the previous year. Nearly half of the customers identified themselves as committed users of the service compared to other transportation methods, and most customers stated that having more service during peak hours and in new communities should be priorities. Sixty-four per cent of respondents supported fare increases to fund service additions. It was concluded that there was a significant increase in overall transit use in 2005, which may have been due to its perceived convenience and the influence of economic factors. It was noted that the increase has not affected customers' perceptions of service performance. 8 tabs., 9 figs.

Corynebacterium striatum infecting a malignant cutaneous lesion: the emergence of an opportunistic pathogen Corynebacterium striatum infectando lesão cutânea maligna: a emergência de um patógeno oportunista

Directory of Open Access Journals (Sweden)

Silvana Vargas Superti

2009-04-01

Full Text Available We described a case of a 27-year old male patient with skin and soft tissue infection of a neoplastic lesion caused by Corynebacterium striatum, an organism which has been rarely described as a human pathogen. Identification was confirmed by DNA sequencing. Successful treatment with penicillin was achieved. The role of the C. striatum as an emerging opportunistic pathogen is discussed.Descrevemos infecção de lesão neoplásica em paciente masculino de 27 anos, envolvendo pele e partes moles, causada por Corynebacterium striatum, um microrganismo raramente descrito como patógeno humano. A identificação foi confirmada por seqüenciamento de DNA. O paciente foi tratado com penicilina, com sucesso. O papel do C. striatum como patógeno oportunista é discutido.

Anotaciones sobre el Clima de los Bosques de Guandal del Delta del Río Patía

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Del Valle Arango Jorge Ignacio

1994-09-01

Full Text Available Este ensayo intenta describir el clima del litoral Pacifico sur colombiano de una manera más precisa y empleando un cúmulo mayor de registros que en otros trabajos anteriores. Con esta base se realiza una clasificación bioclimática para los bosques de guandal del delta del río Patía. En cuanto a la lluvia se hace énfasis no sólo en los promedios mensuales y anuales sino en su oscilación y desviaciones estándar con el fin de evidenciar lo variable de tan importante factor climático. Finalmente se elaboran isoyetas para la región las cuales consideramos consistentes con la información disponible.

Bridging the Transition Gap

Science.gov (United States)

2013-05-23

period and provide recommendations to guide future research and policy development. 4 DEFINING THE TRANSITIONAL SECURITY GAP There have been...BRIDGING THE TRANSITION GAP A Monograph by MAJ J.D. Hansen United States Army School of Advanced Military Studies United States Army...suggestions for reducing this burden to Department of Defense, Washington Headquarters Services, Directorate for Information Operations and Reports (0704

Leaving the Parental Nest: Adjustment Problems, Attachment Representations, and Social Support during the Transition from High School to Military Service

Science.gov (United States)

Scharf, Miri; Mayseless, Ofra; Kivenson-Baron, Inbal

2011-01-01

Adjustment to the transition from high school to military service in Israel was examined in a longitudinal study with a sample of 120 late-adolescent girls. During their senior year in high school (Time 1) the young women were administered the Adult Attachment Interview. Their coping and adjustment to the new environment were assessed (at two…

Eliminación de patógenos en biosólidos por estabilización alcalina Eliminating pathogens in biosolids by alkaline stabilization

Directory of Open Access Journals (Sweden)

Patricia Torres Lozada

2009-07-01

Full Text Available La Planta de Tratamiento de Aguas Residuales de Cañaveralejo -PTAR-C de Cali- Colombia, produce alrededor de 100 t/día de biosólidos que, aunque no tienen restricción por metales pesados, son clase B por el nivel de microorganismos patógenos y parásitos. En un diseño completamente al azar, conformado por seis tratamientos con su respectivo duplicado, se evaluó la estabilización alcalina con dosis del 9% peso a peso de cal viva e hidratada, aplicada a pilas de 0.5 t de biosólidos húmedos (66.5% y secos a temperatura ambiente (25 - 31°C durante 72 h (humedad 50.1%. Con la estabilización alcalina el pH aumentó a valores superiores a 12 unidades durante el tiempo suficiente para garantizar la reducción de patógenos y parásitos, alcanzando un material clase A; sin embargo, el biosólido seco facilitó la formación de grumos que dificultaron las labores de homogenización del sustrato con los alcalinizantes, factor indeseable para la eficiente reducción de patógenos.The Cañaveralejo wastewater treatment plant (PTAR-C based in Cali-Colombia, produces almost 100 t-day-1 of biosolids. Although do not have heavy metals restrictions, it is class B for high contents of pathogens microorganisms and parasites. The alkali stabilization was done with a 9% of dose (w/w of quicklime and hydrated lime applied to different 0.5 ton piles of wet biosolids (66.5% humidity and dry biosolids an environmental temperature (25-31°C for 72 hours (50.1% humidity. The experiment had a completely randomized design and it was composed by 6 treatments with their respective duplicated. With the alkali stabilization, the pH increments above 12 units during enough time to assure pathogens and parasites reduction in order to achieve a class A material level. On the other hand, the dry biosolids facilitate the conditions for lumps formation that reduce the homogenization of the substrate with the alkali material, which it is and undesirable factor for pathogen

Protocol for a cohort study of adolescent mental health service users with a nested cluster randomised controlled trial to assess the clinical and cost-effectiveness of managed transition in improving transitions from child to adult mental health services (the MILESTONE study)

DEFF Research Database (Denmark)

Singh, Swaran P.; Tuomainen, Helena; Girolamo, Giovanni De

2017-01-01

of 840 participants randomised in a 1:2 intervention to control are required, providing 89% power to detect a difference in HoNOSCA score of 0.30 SD. The addition of 210 recruits for the cohort study ensures sufficient power for studying predictors, resulting in 1050 participants and an approximate 1...... Healthcare) study evaluates the longitudinal course and outcomes of adolescents approaching the transition boundary (TB) of their CAMHS and determines the effectiveness of the model of managed transition in improving outcomes, compared with usual care. Methods and analysis This is a cohort study......:3 randomisation. Ethics and dissemination The study protocol was approved by the UK National Research Ethics Service (15/WM/0052) and equivalent ethics boards in participating countries. Results will be reported at conferences, in peer-reviewed publications and to all relevant stakeholder groups. Trial...

A Novel Trip Coverage Index for Transit Accessibility Assessment Using Mobile Phone Data

Directory of Open Access Journals (Sweden)

Zhengyi Cai

2017-01-01

Full Text Available Transit accessibility is an important measure on the service performance of transit systems. To assess whether the public transit service is well accessible for trips of specific origins, destinations, and origin-destination (OD pairs, a novel measure, the Trip Coverage Index (TCI, is proposed in this paper. TCI considers both the transit trip coverage and spatial distribution of individual travel demands. Massive trips between cellular base stations are estimated by using over four-million mobile phone users. An easy-to-implement method is also developed to extract the transit information and driving routes for millions of requests. Then the trip coverage of each OD pair is calculated. For demonstrative purposes, TCI is applied to the transit network of Hangzhou, China. The results show that TCI represents the better transit trip coverage and provides a more powerful assessment tool of transit quality of service. Since the calculation is based on trips of all modes, but not only the transit trips, TCI offers an overall accessibility for the transit system performance. It enables decision makers to assess transit accessibility in a finer-grained manner on the individual trip level and can be well transformed to measure transit services of other cities.

Tout cela est bien quelque chose: Digital Preservation Today: how European Commission programmes and policy have brought us here: Festschrift for Patricia (Pat Manson

Directory of Open Access Journals (Sweden)

Janet Delve

2017-05-01

Full Text Available Patricia (Pat Manson worked with the European Commission's (EC’s research programmes from the early 1990s, initially as project officer (December 1991-March 2003 and then as Head of Unit (April 2003-2011 for Cultural Heritage and Technology Enhanced Learning which was part of the Directorate General Information Society and Media. The unit focused primarily on research in digital libraries, digital preservation, and in the use of ICTs for improving learning, but was also involved in the development of the i2010 digital libraries policies and actions. Prior to joining the Commission, she worked in the UK providing a national advisory and market watch service to libraries on the use of new technologies. She is now Head of the Inclusion, Skills & Youth Unit of the EC’s Directorate General for Communication Networks, Content and Technology (DG CONNECT, where the unit’s goal is to ensure that citizens, especially youth and those at risk of exclusion, are best able to benefit from the Internet and have the necessary skills so to do. This article sets out Pat’s leadership of EC-funded Digital Preservation, and examines her legacy in terms of lasting best practices, contributions to standardisation activities etc.

Perfiles de resistencia a antibióticos y metales pesados en Pseudomonas aeruginosa potencialmente patógenas aisladas de agua de uso agrícola

Directory of Open Access Journals (Sweden)

Oscar G. Gutiérrez Cárdenas

2017-01-01

Full Text Available El 70% de l agua a nivel mundial se destina principalmente para las actividades agrícolas. Sin embargo, debido al crecimiento descontrolado de los asentamientos urbanos se ha acentuado la escasez y contaminación de los cuerpos de agua superficiales, de tal forma que cada vez este líquido de buena calidad es más escaso para la agricultura. Uno de los pri n cipa les contaminantes son las bacterias potencialmente patógenas resistentes a los antibiót i cos. Pseudomonas aeruginosa es una bacteria que se encuentra normalmente en el agua y suelo, es patógeno de animales y plantas. Esta bacteria se ha considerado un fenóm eno de resistencia debido a la diversidad de mecanismos que posee, por lo cual representa un rie s go potencial para la p o blación. Método : Se colectaron muestras de agua de uso agrícola, a partir de las cuales se aislaron e identificaron a nivel bioquímico y molecular P. aeruginosa . En estas bacterias se determinó la distribución de 6 genes de virulencia por PCR. Mediante ensayos de difusión en disco y m i crodilución se analizó la resistencia a 20 antibióticos. Además mediante ensayos de microd i lución se dete rminó la resistencia a metales pesados. Resultados : Se identificaron a nivel bioquímico y molecular 46 aislados de P. aeruginosa, éstas son potencialmente patógenas ya que en ellas se detectó la presencia de los genes de virule n cia algD y toxA (100%, las B (97.8%, plcH (95.6%, plcN (91.3% y exoS (89.1%. Dichas bacterias presentaron altos índices de resistencia a ampicilina, ceftriaxona, cloranfen i col, cefalotina, cefotaxima, nitrofurantoína, kanamicina , estreptomicina y tetraciclina. De igual forma fue ron muy susceptibles a ceftazidima, gentamicina, imipenem, ticarcilina, a z treonam, levofloxacina, netilmicina y carbenicilina. Todas las bacterias fueron multirresiste n tes ya que toleraron entre 8 y 11 antibióticos. De acuerdo a los patrones de resistencia obse r vados, las bacterias se

Occupational therapy in transitioning adolescents to post-secondary activities.

Science.gov (United States)

Spencer, Janet E; Emery, Lynnda J; Schneck, Colleen M

2003-01-01

The purpose of this study was to examine the perceptions of special education directors on the current role of occupational therapy in high school transition programs for adolescent students with disabilities. Additionally, barriers to providing occupational therapy services and perceptions about new occupational therapy services were examined. A mailed questionnaire was administered to all special education directors in a rural state in the United States. One hundred and four (57.5%) responses were received. Descriptive statistics were generated with an emphasis on percentages to examine current occupational therapy services in high school transition programs and barriers to service delivery. In this study, occupational therapists provided less than one fifth of transition services in high schools for students with disabilities. They provided more assistive technology consults (30.3%), task or environmental modification (25.8%), and Individualized Education Plan (IEP) and Individualized Transition Plan (ITP) planning (20%) than other providers. Barriers to occupational therapy use included funding, lack of inter-agency planning, and lack of parent participation. About 35% of special education directors suggested that additional occupational therapy services were needed for adolescents with cognitive disabilities and for job performance and related work skills programming. Occupational therapists in this study provided ancillary services to high school students with disabilities with greater emphasis on technology, task or environmental modification, and IEP or ITP planning, as perceived by special evaluation directors.

Using connectivity for measuring equity in transit provision

DEFF Research Database (Denmark)

Kaplan, Sigal; Popoks, Dmitrijs; Prato, Carlo Giacomo

2014-01-01

. In addition, transit connectivity weighs the impedance components according to their relative importance to travelers. The assessment of equity was performed for the multi-modal transit system in the Greater Copenhagen Area, renowned for its transit-oriented finger-plan. The assessment method used a GIS...... representation of the network (i.e., service lines, timetables, metro stations, train stations, and bus stops), and transit assignment results (i.e., level-of-service times, passenger flows). The assessment method proved effective in calculating location-based and potential-accessibility measures and Gini...... coefficients of inequality in the Greater Copenhagen Area. Results show that the transit-oriented development contributes to spatial equity with high connectivity in densely populated zones, vertical equity with comparable connectivity in high income and low income zones, inter-generational equity with good...

Performance of Urban Transit in Jordan

OpenAIRE

Dr. Hashem R. Al-Masaeid; Amir Shtayat

2016-01-01

Urban public transit has essential and active role for sustainable and balanced socio-economic and environmental development. This study investigated the performance of urban public transit services in three major cities in Jordan, including Amman, Irbid, and Zarqa. Accessibility, mobility, productivity, punctuality, waiting time and comfort of public transit were investigated in the study. Data were obtained from Land Transport RegulatoryCommission of Jordan, municipalities, and ...

National Fuel Cell Bus Program: Accelerated Testing Evaluation Report and Appendices, Alameda-Contra Costa Transit District (AC Transit)

Energy Technology Data Exchange (ETDEWEB)

Chandler, K.; Eudy, L.

2009-01-01

This is an evaluation of hydrogen fuel cell transit buses operating at AC Transit in revenue service since March 20, 2006 compared to similar diesel buses operating from the same depot. This evaluation report includes results from November 2007 through October 2008. Evaluation results include implementation experience, fueling station operation, fuel cell bus operations at Golden Gate Transit, and evaluation results at AC Transit (bus usage, availability, fuel economy, maintenance costs, and roadcalls).

Transit Car Performance Comparison, State-of-the-Art Car vs. PATCO Transit Car, NYCTA R-46, MBTA Silverbirds

Science.gov (United States)

1978-02-01

The first phase of this contract authorized the design, development, and demonstration of two State-Of-The-Art Cars (SOAC). This document reports on the gathering of comparative test data on existing in-service transit cars. The three transit cars se...

Dermatófitos: interação patógeno-hospedeiro e resistência a antifúngicos Dermatophytes: host-pathogen interaction and antifungal resistance

Directory of Open Access Journals (Sweden)

Nalu Teixera de Aguiar Peres

2010-10-01

Full Text Available As micoses cutâneas estão entre as infecções mais comuns em humanos e se tornaram um importante problema de saúde pública, principalmente por causarem infecções invasivas em pacientes imunodeprimidos. Durante a infecção, a interação dermatófito-hospedeiro desencadeia adaptações metabólicas específicas que permitem aos patógenos aderirem e penetrarem no tecido, remodelando seu metabolismo para captar nutrientes e superar os mecanismos de defesa do hospedeiro. Esse remodelamento metabólico e a inter-relação entre metabolismo, morfogênese e resposta ao estresse são importantes fatores que estão sendo intensamente avaliados em diversos patógenos. As células do hospedeiro também respondem aos estímulos do patógeno, ativando vias de sinalização intracelular que culminam no desencadeamento de uma resposta imune contra o agente infeccioso. O entendimento molecular dessas respostas metabólicas pode ajudar no estabelecimento de novas estratégias terapêuticas. Nesta revisão, são abordados diferentes aspectos da biologia dos dermatófitos, com ênfase na interação dermatófito-hospedeiro e nos mecanismos de resistência a antifúngicos.Cutaneous mycoses are among the most common infections in humans and have become an important public health issue because they cause invasive infections in immunocompromised patients. During the infectious process, dermatophyte-host interactions trigger specific metabolic adaptations that allow the pathogen to adhere to and penetrate the host tissue, scavenge nutrients, and overcome the host defense mechanisms. This metabolic shift and the interplay between metabolism, morphogenesis and stress response are important factors that have been extensively studied in several pathogens. Host cells also respond to the pathogen stimuli by activating intracellular signaling pathways that trigger the immune response against the infectious agent. The comprehension of the molecular aspects of these

The transition of young adults with lifelong urological needs from pediatric to adult services: An international children's continence society position statement.

Science.gov (United States)

Bower, Wendy F; Christie, Deborah; DeGennaro, Mario; Latthe, Pallavi; Raes, Ann; Romao, Rodrigo L P; Taghizadeh, Arash; Wood, Dan; Woodhouse, Christopher R J; Bauer, Stuart B

2017-03-01

Children with urinary tract disorders managed by teams, or individual pediatricians, urologists, nephrologists, gastroenterologists, neurologists, psychologists, and nurses at some point move from child-centered to adult-centered health systems. The actual physical change is referred to as the transfer whilst the process preceding this move constitutes transition of care. Our aims are twofold: to identify management and health-service problems related to children with congenital or acquired urological conditions who advance into adulthood and the clinical implications this has for long-term health and specialist care; and, to understand the issues facing both pediatric and adult-care clinicians and to develop a systems-approach model that meets the needs of young adults, their families and the clinicians working within adult services. Information was gleaned from presentations at an International Children's Continence Society meeting with collaboration from the International Continence Society, that discussed problems of transfer and transitioning such children. Several specialists attending this conference finalized this document identifying issues and highlighting ways to ease this transition and transfer of care for both patients and practitioners. The consensus was, urological patients with congenital or other lifelong care needs, are now entering adulthood in larger numbers than previously, necessitating new planning processes for tailored transfer of management. Adult teams must become familiar with new clinical problems in multiple organ systems and anticipate issues provoked by adolescence and physical growth. During this period of transitional care the clinician or team assists young patients to build attitudes, skills and understanding of processes needed to maximize function of their urinary tract-thus taking responsibility for their own healthcare needs. Preparation must also address, negotiating adult health care systems, psychosocial, educational or

Chemical and sensory quality of sheep liver pâté prepared with ‘variety meat’Qualidade química e sensorial de patê de fígado ovino elaborado com subprodutos comestíveis

Directory of Open Access Journals (Sweden)

Deborah Amaral

2013-09-01

Full Text Available Many edible meat by-products produced from sheep slaughter are often wasted but represent excellent sources of many nutrients. The preparation of pâté may be an alternative use for this raw material and may contribute to the development of a sheep sector by offering new products to the consumer market. The objective of this work was to produce and evaluate the quality of sheep pâté made with blood, liver and trimmed meat. The pâté formulation was composed of 12% meat, 25% liver, 13% blood, 20% water and 30% fat, as well as spices and seasoning. The product had high iron content (9.0 mg/100 g. The measured levels of essential amino acids exceeded the recommended values for adults. The sheep liver pâté showed a significant percentage of linoleic acid (16.68%, which is essential to the human body. The pâté produced was in accordance with the requirements of the Brazilian legislation regarding chemical and microbiological parameters, able to be edible, and showed good sensory acceptance. This study suggests that the development of sheep liver pâté is a viable alternative to add value to edible sheep slaughter by-products by generating a product with high nutritional value. Subprodutos comestíveis produzidos a partir do abate de ovinos são muitas vezes desperdiçado, mas representam excelentes fontes de muitos nutrientes. A preparação de patê pode ser uma alternativa para utilização desta matéria-prima e pode contribuir para o desenvolvimento do setor da ovinocultura, oferecendo novos produtos para o mercado consumidor. O objetivo deste trabalho foi produzir e avaliar a qualidade de patê ovino feito com fígado, sangue e retraços de carne. A formulação do patê foi composta de 12 % de carne, 25% de fígado, 13 % de sangue, 20% de água e 30% de gordura, bem como especiarias e condimentos. O produto tinha alto teor de ferro (9,0 mg/100 g. Os níveis medidos de aminoácidos essenciais excederam os valores recomendados para

Administration of care to older patients in transition from hospital to home care services: home nursing leaders' experiences

Directory of Open Access Journals (Sweden)

Dale B

2013-10-01

Full Text Available Bjørg Dale,1 Sigrun Hvalvik21Centre for Caring Research – Southern Norway, Faculty of Health and Sport Sciences, University of Agder, Grimstad, 2Centre for Caring Research – Southern Norway, Faculty of Health and Social Studies, Telemark University College, Porsgrunn, NorwayBackground: Older persons in transition between hospital and home care services are in a particularly vulnerable situation and risk unfortunate consequences caused by organizational inefficiency. The purpose of the study reported here was to elucidate how home nursing leaders experience the administration of care to older people in transition from hospital to their own homes.Methods: A qualitative study design was used. Ten home nursing leaders in two municipalities in southern Norway participated in individual interviews. The interview texts were audio taped, transcribed verbatim and analyzed by use of a phenomenological-hermeneutic approach.Results: Three main themes and seven subthemes were deduced from the data. The first main theme was that the home nursing leaders felt challenged by the organization of home care services. Two subthemes were identified related to this. The first was that the leaders lacked involvement in the transitional process, and the second was that they were challenged by administration of care being decided at another level in the municipality. The second main theme found was that the leaders felt that they were acting in a shifting and unsettled context. Related to this, they had to adjust internal resources to external demands and expectations, and experienced lack of communication with significant others. The third main theme identified was that the leaders endeavored to deliver care in accordance with professional values. The two related subthemes were, first, that they provided for appropriate internal systems and routines, and, second, that they prioritized available professional competence, and made an effort to promote a professional

Pārdošanas veicināšana kā patērētāju uzvedības un lēmumu pieņemšanas ietekmētājs Latvijas pārtikas mazumtirdzniecības nozarē.

OpenAIRE

Afoņičeva, Oksana

2016-01-01

Maģistra darba: “Pārdošanas veicināšana kā patērētāju uzvedības un lēmumu pieņemšanas ietekmētājs Latvijas pārtikas mazumtirdzniecības nozarē” mērķis ir, izvērtējot pārdošanas veicināšanas ietekmi uz patērētāju uzvedību, lēmuma pieņemšanas procesu un uz patērētāju lojalitātes veidošanu, rast priekšlikumus pārdošanas veicināšanas iespējām pārtikas produktu zīmoliem. Darbs sastāv no četrām nodaļām- divām teorētiskajām, analītiskās un empīriskās. Pirmā izvirzītā hipotēze tiek apstiprināta, pama...

Linguistic Norms at the Crossover: The Verbal Tenses and Modes, and the Structure of the Predicate in «Libro decimosexto» from Comentarios de erudición by Bartolomé Jiménez Patón

Directory of Open Access Journals (Sweden)

Juan Miguel Monterrubio Prieto

2013-11-01

Full Text Available This study examines verb modes and tenses as well as the predicate structure in «Libro decimosexto» of Bartolomé Jiménez Patón’s Comentarios de erudición in an effort to demonstrate how the text straddles the line between Medieval and Golden Age norms. Jiménez Patón, thus, combines traits already considered archaic at the time, due perhaps to his solid training in grammar and his linguistic awareness, with those modern solutions which, towards the end of the 1500’s, were forging the new Spanish language (that of the «plain style», which he championed, one that was gradually being refined in order to take its place as the language of culture.

Network and user interface for PAT DOME virtual motion environment system

Science.gov (United States)

Worthington, J. W.; Duncan, K. M.; Crosier, W. G.

1993-01-01

The Device for Orientation and Motion Environments Preflight Adaptation Trainer (DOME PAT) provides astronauts a virtual microgravity sensory environment designed to help alleviate tye symptoms of space motion sickness (SMS). The system consists of four microcomputers networked to provide real time control, and an image generator (IG) driving a wide angle video display inside a dome structure. The spherical display demands distortion correction. The system is currently being modified with a new graphical user interface (GUI) and a new Silicon Graphics IG. This paper will concentrate on the new GUI and the networking scheme. The new GUI eliminates proprietary graphics hardware and software, and instead makes use of standard and low cost PC video (CGA) and off the shelf software (Microsoft's Quick C). Mouse selection for user input is supported. The new Silicon Graphics IG requires an Ethernet interface. The microcomputer known as the Real Time Controller (RTC), which has overall control of the system and is written in Ada, was modified to use the free public domain NCSA Telnet software for Ethernet communications with the Silicon Graphics IG. The RTC also maintains the original ARCNET communications through Novell Netware IPX with the rest of the system. The Telnet TCP/IP protocol was first used for real-time communication, but because of buffering problems the Telnet datagram (UDP) protocol needed to be implemented. Since the Telnet modules are written in C, the Adap pragma 'Interface' was used to interface with the network calls.

Vocational and Transition Interventions for Adolescents and Young Adults with Emotional or Behavioral Disorders.

Science.gov (United States)

Bullis, Michael; Cheney, Douglas

1999-01-01

This article describes characteristics of adolescents with emotional and behavioral disorders, transition outcomes for these students, model transition programs, and key transition service delivery components, including: intake and functional skill assessment, personal future planning, wraparound social services, competitive employment, flexible…

Understanding transition performance during offshore IT outsourcing

NARCIS (Netherlands)

E. Beulen (Erik); V. Tiwari (Vinay); H.W.G.M. van Heck (Eric)

2011-01-01

textabstractPurpose - Within an IT outsourcing relationship, transition represents a critical and complex phase that starts immediately after contract signing. Transition involves handing over outsourced activities from client firm to service provider firm and accompanies a new way of operating. The

Strategic framework for education and training in Quality by Design (QbD) and process analytical technology (PAT)

DEFF Research Database (Denmark)

de Matas, Marcel; De Beer, Thomas; Folestad, Staffan

2016-01-01

is not prescriptive and is not aimed at describing specific course content in detail. It should however be used as a point of reference for those institutions delivering pharmaceutical based educational courses, to ensure that the necessary skills, knowledge and experience for successful pharmaceutical development...... advanced science and technology coupled with the application of modern Quality by Design (QbD) principles. In order that Europe keeps pace with these changes and sustains its position as major player in the development and commercialization of medicines, it is essential that measures are put in place...... to maintain a highly skilled workforce. A number of challenges however exist to equipping academic, industrial and health agency staff with the requisite knowledge, skills and experience to develop the next generation of medicines. In this regard, the EUFEPS QbD and PAT Sciences Network has proposed...

NPS National Transit Inventory and Performance Report, 2016

Science.gov (United States)

2017-12-01

This document summarizes key highlights and performance measures relating to the National Park Service (NPS) 2016 National Transit Inventory, by presenting data for NPS transit systems and vehicles nationwide. These highlights and performance measure...

Hormone signaling linked to silkmoth sex pheromone biosynthesis involves Ca2+/calmodulin-dependent protein kinase II-mediated phosphorylation of the insect PAT family protein Bombyx mori lipid storage droplet protein-1(BmLsd)

Science.gov (United States)

The structurally-related members of the PAT family of proteins, which are so name based on similarity amongst perilipin, adipophilin/adipocyte differentiation-related protein (ADRP), and tail-interacting protein of 47 kilodaltons (TIP47), are cytoplasmic lipid droplet (LD)-associated proteins charac...

Estudio comparativo entre aislados clínicos y no clínicos de S. cerevisiae y su papel como patógeno emergente.

OpenAIRE

Llanos Frutos, Rosa de

2007-01-01

RESUMEN La levadura Saccharomyces cerevisiae es la especie más utilizada desde un punto de vista biotecnológico. En la industria agroalimentaria interviene en la elaboración de pan y bebidas alcohólicas como el vino y la cerveza, además se emplea como suplemento dietético y como agente probiótico bajo el nombre de S. cerevisiae var. boulardii. A pesar de sus propiedades beneficiosas, S. cerevisiae se considera actualmente una levadura patógena oportunista emergente de baja virulencia, capa...

[Status of diagnosis and treatment devices of acupuncture based on SooPAT and bibliometrics in China].

Science.gov (United States)

Bai, Lin; Ren, Yulan; Guo, Taipin; Chen, Lin; Zhou, Yumei; Feng, Shuwei; Li, Ji; Liang, Fanrong

2016-11-12

To perform a bibliometrics analysis on patent literature regarding diagnosis and treatment devices of acupuncture in China, aiming to provide references for the development of diagnosis and treatment devices of acupuncture. Based on SooPAT, a patent database, the patent literature regarding diagnosis and treatment devices of acupuncture in China was collected. With bibliometrics methods, the annual distribution of type, quantity, classification and content of diagnosis and treatment devices of acupuncture were analyzed. The number of acupuncture diagnosis and treatment devices reached its peak in 2012 and 2013 in China. The A61N in patent and utility model patent were the most, which were mainly related to electrotherapy, magnetic therapy, radioactive therapy and ultrasound therapy, etc. The main content was acupuncture treatment devices and meridian treatment devices. The 24-01 in design patent was the most, involving fixation devices used by doctors, hospitals and laboratories, etc. Currently the majority of diagnosis and treatment devices of acupuncture is therapeutic apparatus, while the acupuncture diagnosis devices are needed.

Service-Dominant Business Engineering with Base/X : Business Modeling Handbook

NARCIS (Netherlands)

Grefen, P.W.P.J.

2015-01-01

Many business domains are currently transitioning towards a service-dominant business setting. After the transition, business will be centered on the provisioning of solution-oriented, composed services to customers. The emphasis shifts from the value of the individual product or service to the

Widening energy access in Africa: Towards energy transition

International Nuclear Information System (INIS)

Sokona, Youba; Mulugetta, Yacob; Gujba, Haruna

2012-01-01

The discussion to widen access to modern energy services has been influential in shaping some of the discussions on energy at the international level. The practice of widening modern energy services access to the poor in Africa is complex, and exacerbated by the dual nature of the energy system across Sub-Saharan Africa where traditional and modern energy systems and practices co-exist. This presents major challenges for policy makers who have to contend with a fragmented energy system, which requires the mobilisation of an array of actors at cross-sectoral levels in order to develop effective institutions and implement innovative policy frameworks. This paper further argues that, the ‘energy access’ discussion needs to take place in the context of energy transitions, giving due consideration to the productive sector as an important vehicle for change. As the link between energy and development is context specific, each African country needs to chart its own energy transition pathway into the future, and there are ample lessons that they can draw from previous energy transitions. - Highlights: ► Lack of access to modern energy services in Africa is an impediment to socio-economic development. ► Widening modern energy services access to the poor in Africa is complex. ► A broader approach to address the ‘energy access’ discourse is required. ► Each African country needs to chart its own energy transition pathway. ► Both fossil and renewable energy systems would be needed for a transition to modern energy sources.

Variability among pathologists in the histological diagnosis of helicobacter pylori infection: is it a subjective diagnosis? Variabilidad entre patólogos en el diagnóstico histológico de la infección por Helicobacter pylori: ¿un diagnóstico subjetivo?

Directory of Open Access Journals (Sweden)

Luis Fernando Arias Restrepo

2006-01-01

Full Text Available Histopathologic diagnosis of Helicobacter pylori (Hp infection is not necessarily easy, and reproducibility is not perfect. Our aim was to determine differences in the frequency of Hp infection according to the pathologists interpreting gastric biopsies in Medellín (Colombia. Materials and methods: All gastric biopsy reports of eight pathologists during one year were reviewed. We excluded cases with intestinal metaplasia, atrophy, dysplasia or carcinoma. We registered patient age, positivity or negativity for H. pylori, and pathologist. We determined the percentage with H. pylori infection and the percentage of each pathologist in order to determine differences. Results: 2.023 cases were included. Each pathologist evaluated a mean of 252.9 ± 154.9 cases (range: 102-445. Patients were 43.5 ± 15.1 years-old (range: 12-90. H. pylori was diagnosed in 1.034 cases (51.1%. The range of positivity according to the pathologist was 38.8-71.1%; mean 51.1% ± 8.7% (p < 0,001. Conclusion: Among pathologists, there is a significant variability in the frequency of diagnosis of H. pylori infection. This result suggests the need to achieve greater homogeneity of concepts and criteria for the diagnosis of this infection, and of its severity. El diagnóstico histológico de la infección por Helicobacter pylori (Hp puede ser difícil, principalmente en casos con pocos microorganismos. Nuestro objetivo fue determinar si hay diferencias significativas en la frecuencia del diagnóstico de la infección por Hp entre patólogos que laboran en Medellín. Materiales y métodos: revisamos todos los informes de biopsias gástricas de ocho patólogos durante un año. Excluimos las biopsias con metaplasia, atrofia, displasia o carcinoma. Registramos la edad del paciente, la presencia o ausencia de Hp y el patólogo que estudió la biopsia. Calculamos el porcentaje de casos con la infección y el porcentaje por patólogo. Finalmente, comparamos estos porcentajes para

Multimodal approach to the international transit transport

Directory of Open Access Journals (Sweden)

D. Bazaras

2003-12-01

Full Text Available In the article not only the problems of multi-modal and inter-modal conveyances in Lithuania and the concept of transit and the transit system stimulating factors are analysed, but also the modelling of transit transport and the flows of the loads are given. The main part of the article comes to the analysis of resent situation of Lithuania. In this part the place of transport sector in the market of transit services is analysed and the transit profit for Lithuanian economy is evaluated. The conclusions and proposals are given at the end of the article.

Extratos vegetais no controle de patógenos em sementes de Pterogyne nitens Tul

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José George Ferreira Medeiros

Full Text Available A demanda por sementes florestais para reflorestamento e outras finalidades poderá se constituir em um meio de disseminação de patógenos, que podem comprometer a qualidade fisiológica das sementes. Assim, objetivou-se avaliar o efeito de extratos naturais de melão-de-são-caetano (Momordica charantia e alamanda (Allamanda blanchetti sobre a micoflora e a fisiologia de sementes de Pterogyne nitens. Os seguintes tratamentos fitossanitários foram avaliados: testemunha (sementes não tratadas; fungicida Captan® (240 g/100 kg, e extratos de melão-de-são-caetano e alamanda nas concentrações de 10, 100, 500 e 1000 ppm. No teste de germinação, avaliaram-se a porcentagem de germinação, a primeira contagem e o índice de velocidade de germinação (IVG. Os extratos vegetais de melão-de-são-caetano e alamanda reduziram a incidência de fungos e aumentaram o percentual de germinação das sementes de P. nitens.

Changes of seasonally dry forest in the Colombian Patía Valley during the early and middle Holocene and the development of a dry climatic record for the northernmost Andes

NARCIS (Netherlands)

González-Carranza, Z.; Berrío, J.C.; Hooghiemstra, H.; Duivenvoorden, J.F.; Behling, H.

2008-01-01

A 450 cm long sediment core was collected from a swamp in the dry forest ecosystem of the Patía Valley in Colombia (02°02′ N, 77° W at 750 m elevation). This core (Potrerillo-2) was analysed using pollen, lithostratigraphy and radiocarbon dates and was correlated with an already existing dataset

From products to services : reflections on the challenges in designing for services

NARCIS (Netherlands)

Bhomer, ten M.; De Lille, C. S. H.; Tomico, O.; Kleinsmann, M.S.

2013-01-01

In this paper we will point to implications for designers who support organizations in the transition process from products to services based business models. These implications are based on four important challenges when designing for services: the designerly mindset, collaboration, empathy with

Incorporating unreliability of transit in transport demand models: theoretical and practical approach

NARCIS (Netherlands)

van Oort, N.; Brands, Ties; de Romph, E.; Aceves Flores, J.

2014-01-01

Nowadays, transport demand models do not explicitly evaluate the impacts of service reliability of transit. Service reliability of transit systems is adversely experienced by users, as it causes additional travel time and unsecure arrival times. Because of this, travelers are likely to perceive a

Special Education Teacher Transition-Related Competencies and Preparation in Saudi Arabia

Science.gov (United States)

Alnahdi, Ghaleb

2014-01-01

Preparing special education teachers to engage in transition services is a critical part of their preparation. This study examined how special education teachers perceive their preparation for transition services in Riyadh, Saudi Arabia. A total of 350 teachers participated in this study. Data were analyzed using a two-way ANOVA. The findings…

Modeling Metropolitan Detroit transit.

Science.gov (United States)

2010-10-01

"The seven-county Southeast Michigan region, that encompasses the Detroit Metropolitan Area, : ranks fifth in population among top 25 regions in the nation. It also ranks among bottom five in : the transit service provided, measured in miles or hours...

Enhancing transit service in rural areas and native american tribal communities : potential mechanisms to improve funding and service.

Science.gov (United States)

2014-08-01

Primary funding for rural transit comes from federal and state Departments of Transportation (DOTs). However, through numerous : surveys, rural transit providers have cited financial constraints as a major limitation to providing adequate desired tra...

Virtual Libraries: Service Realities.

Science.gov (United States)

Novak, Jan

This paper discusses client service issues to be considered when transitioning to a virtual library situation. Themes related to the transitional nature of society in the knowledge era are presented, including: paradox and a contradictory nature; blurring of boundaries; networks, systems, and holistic thinking; process/not product, becoming/not…

Variação da contagem de células somáticas em vacas leiteiras de acordo com patógenos da mastite Somatic cell counts variation in dairy cows according to mastitis pathogens

Directory of Open Access Journals (Sweden)

G.N. Souza

2009-10-01

Full Text Available Avaliou-se o efeito de patógenos da mastite sobre a contagem de células somáticas (CCS em leite. Foram coletadas 3.987 amostras de leite de 2.657 animais oriundos de 24 rebanhos leiteiros localizados nos estados do Rio de Janeiro e Minas Gerais. As amostras de leite foram usadas para CCS e identificação de patógenos da mastite. Estatísticas descritivas, teste T para amostras independentes e modelo linear generalizado foram usados para análise dos dados. O modelo linear generalizado identificou os efeitos de rebanho, animal dentro de rebanho, ordem de parto, estação do ano e infecção intramamária causada por Streptococcus agalactiae e Streptococcus spp. que não S. agalactiae como significativos na variação da CCS. O efeito de animal dentro de rebanho foi maior que o efeito de rebanho. S. agalactiae foi o patógeno responsável pelo maior aumento da CCS em vacas e apresentou em média 1.520.000 células/mL. Foi observado efeito específico dos patógenos na variação da CCS.The influence of mastitis pathogens on variation of milk somatic cell count (SCC was evaluated. Three thousand nine hundred eighty-seven milk samples were colected from 2,657 dairy cows in 24 herds located in the states of Minas Gerais and Rio de Janeiro. The milk samples were used to SCC and identification of mastitis pathogens. Descriptive statistics, T test for independent samples, and generalized linear model were used to data analysis. The generalized linear model identified the effects of herd, animal within herd, parity, year season, intramammary infection, and infection caused by Streptococcus agalactiae and Streptococcus spp. except S. agalactiae as significant on SCC variation. The effect of animal within herd was higher than the effect of herd. S. agalactiae was the pathogen responsible for higher SCC increasing and presented the average of 1,520,000 cells/mL. The specific effect on SCC variation was observed in the study.

Radiotherapy services in countries in transition: gross national income per capita as a significant factor

International Nuclear Information System (INIS)

Levin, Victor; Tatsuzaki, Hideo

2002-01-01

Background and purpose: The acquisition of radiotherapy by countries in transition (CITs) is an evolutionary process from having no resources whatsoever, to meeting the standards adopted by well-developed countries. The influence of the economic ability of a country to acquire and sustain this technology has intuitively been accepted as a major factor but has not before been subjected to analysis for a large group of countries. This information has been analysed to provide guidance to countries commencing and expanding radiotherapy services. Material and methods: The number of linear accelerators and 60 Co megavoltage teletherapy machines in 72 CITs, those with gross national income per capita (GNI/cap) $12000 pa were expressed as machines per million population (MEV/mil) and used as an index of the ability of the country to provide a service. This figure was related to GNI/cap. The average populations of 24 further countries without radiotherapy were compared with 21 countries with radiotherapy facilities having the same range of GNI/cap. Results: The relationship log 10 MEV/mil=-2.90+0.85 log 10 GNI/cap was identified between the machines and income. Also verified was that small low income countries were less likely to have the technology than those with large populations. Conclusions: The increase in the number of teletherapy machines is closely linked to the GNI/cap of a country. Our sample of well developed countries failed to demonstrate a levelling off of equipment acquisition with income. In the lower income group, smaller countries were less likely to have radiotherapy services than those with large populations

50 CFR 14.109 - Care in transit.

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Care in transit. 14.109 Section 14.109 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR TAKING... Wild Mammals and Birds to the United States § 14.109 Care in transit. (a) During transportation to the...

50 CFR 14.133 - Care in transit.

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Care in transit. 14.133 Section 14.133 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR TAKING..., Sea Otters, Pinnipeds, and Polar Bears) § 14.133 Care in transit. (a) Any marine mammal shall be...

50 CFR 14.123 - Care in transit.

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Care in transit. 14.123 Section 14.123 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR TAKING... transit. (a) A primate shall be observed for signs of distress and given food and water according to the...

BC Transit Fuel Cell Bus Project Evaluation Results: Second Report

Energy Technology Data Exchange (ETDEWEB)

Eudy, L.; Post, M.

2014-09-01

Second report evaluating a fuel cell electric bus (FCEB) demonstration led by British Columbia Transit (BC Transit) in Whistler, Canada. BC Transit is collaborating with the California Air Resources Board and the U.S. Department of Energy's National Renewable Energy Laboratory to evaluate the buses in revenue service. NREL published its first report on the demonstration in February 2014. This report is an update to the previous report; it covers 3 full years of revenue service data on the buses from April 2011 through March 2014 and focuses on the final experiences and lessons learned.

Transition to the Cloud

DEFF Research Database (Denmark)

Hedman, Jonas; Xiao, Xiao

2016-01-01

The rising of cloud computing has dramatically changed the way software companies provide and distribute their IT product and related services over the last decades. Today, most software is bought offthe-shelf and distributed over the Internet. This transition is greatly influencing how software...... companies operate. In this paper, we present a case study of an ERP vendor for SMB (small and mediumsize business) in making a transition towards a cloud-based business model. Through the theoretical lens of ecosystem, we are able to analyze the evolution of the vendor and its business network as a whole......, and find that the relationship between vendor and Value-added-Reseller (VAR) is greatly affected. We conclude by presenting critical issues and challenges for managing such cloud transition....

Use of Mental Health Services in Transition Age Youth with Bipolar Disorder

Science.gov (United States)

Hower, Heather; Case, Brady G.; Hoeppner, Bettina; Yen, Shirley; Goldstein, Tina; Goldstein, Benjamin; Birmaher, Boris; Weinstock, Lauren; Topor, David; Hunt, Jeffrey; Strober, Michael; Ryan, Neal; Axelson, David; Gill, Mary Kay; Keller, Martin B.

2013-01-01

Objectives There is concern that treatment of serious mental illness in the United States declines precipitously following legal emancipation at age 18 years and transition from specialty youth clinical settings. We examined age transition effects on treatment utilization in a sample of youth with bipolar disorder. Methods Youth with bipolar disorder (N = 413) 7–18 years of age were assessed approximately twice per year (mean interval 8.2 months) for at least 4 years. Annual use of any individual, group, and family therapy, psychopharmacology visits, and hospitalization at each year of age, and monthly use from ages 17 through 19 years, were examined. The effect of age transition to 18 years on monthly visit probability was tested in the subsample with observed transitions (n = 204). Putative sociodemographic moderators and the influence of clinical course were assessed. Results Visit probabilities for the most common modalities—psychopharmacology, individual psychotherapy, and home-based care— generally fell from childhood to young adulthood. For example, the annual probability of at least one psychopharmacology visit was 97% at age 8, 75% at age 17, 60% at age 19, and 46% by age 22. Treatment probabilities fell in transition-age youth from age 17 through 19, but a specific transition effect at age 18 was not found. Declines did not vary based on sociodemographic characteristics and were not explained by changing severity of the bipolar illness or functioning. Conclusions Mental health treatment declined with age in this sample of youth with bipolar disorder, but reductions were not concentrated during or after the transition to age 18 years. Declines were unrelated to symptom severity or impairment. PMID:24241500

47 CFR 27.1233 - Reimbursement costs of transitioning.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false Reimbursement costs of transitioning. 27.1233 Section 27.1233 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES... Policies Governing the Transition of the 2500-2690 Mhz Band for Brs and Ebs § 27.1233 Reimbursement costs...

Three-Dimensional Service Value Creation Model Based on Multidisciplinary Framework: Service Value Transition in Flower Tourism and Robotized Music Appreciation Services

OpenAIRE

Nakamura, Kotaro; Imahori, Takahiro; Ikawa, Yasuo

2010-01-01

This paper is focused on the process of value creation in the service business and on the shift of service value created in actual service businesses. The analysis is used to demonstrate proposed models for explaining this shift. Service value is successfully created when customers enjoy the benefits of services proposed through a system of service businesses. The model visualizes the shift of service value, focusing on the three axes of width (of the place for service providing/usage in the ...

Environmental, behavioral, and psychological predictors of transit ridership: Evidence from a community intervention

Science.gov (United States)

Brown, Barbara B.; Werner, Carol M.; Smith, Ken R.; Tribby, Calvin P.; Miller, Harvey J.; Jensen, Wyatt A.; Tharp, Doug

2016-01-01

Understanding who takes advantage of new transit (public transportation) interventions is important for personal and environmental health. We examine transit ridership for residents living near a new light rail construction as part of “complete street,” pedestrian-friendly improvements. Adult residents (n=536) completed surveys and wore accelerometer and GPS units that tracked ridership before and after new transit service started. Transit riders were more physically active. Those from environments rated as more walkable were likely to be continuing transit riders. Place attachment, but not perceived physical incivilities on the path to transit, was associated with those who continued to ride or became new riders of transit. This effect was mediated through pro-city attitudes, which emphasize how the new service makes residents eager to explore areas around transit. Thus, place attachment, along with physical and health conditions, may be important predictors and promoters of transit use. PMID:27672237

Morfologia de Plântulas e Controle de Patógenos em Sementes de Cordia trichotoma

Directory of Open Access Journals (Sweden)

Álvaro Luis Pasquetti Berghetti

Full Text Available O presente trabalho tem como objetivo descrever morfologicamente o desenvolvimento das plântulas de Cordia trichotoma, determinar a influência dos tratamentos de semente e do substrato na redução da incidência de patógenos, assim como avaliar o potencial germinativo das sementes. O teste de sanidade foi realizado em esquema bifatorial 2 × 4 (dois tipos de beneficiamento e quatro tratamentos de sementes. O teste de germinação representou um esquema trifatorial 2 × 4 × 3 (dois beneficiamentos, quatro tratamentos de sementes e três substratos. O início da germinação ocorreu no 18° dia após a instalação do teste. A germinação das sementes é do tipo epígea, com plântula fanerocotiledonar. O percentual germinativo das sementes é superior quando é retirado todo o perianto, independentemente do substrato utilizado e do tratamento. O tratamento com Captan® reduziu a incidência de fungos dos gêneros Alternaria spp., Trichoderma spp., Rhizopus spp.

Veterans' Employment and Training Service

Science.gov (United States)

... Find a Job Veterans.Gov Apprenticeship Occupations and Careers Women Who Served Programs & Services Transition GPS Frequently Asked Questions Hire a Veteran Find qualified Veterans Policy & Compliance Employer Toolkit Apprenticeships HIRE Vets Medallion Program Service Providers Grants & ...

Virtual Libraries: Service Realities.

Science.gov (United States)

Novak, Jan

2002-01-01

Discussion of changes in society that have resulted from information and communication technologies focuses on changes in libraries and a new market for library services with new styles of clients. Highlights client service issues to be considered when transitioning to a virtual library situation. (Author/LRW)

[Transition from pediatric to adult health care services for adolescents with chronic diseases: Recommendations from the Adolescent Branch from Sociedad Chilena de Pediatría].

Science.gov (United States)

Zubarew, Tamara; Correa, Loreto; Bedregal, Paula; Besoain, Carolina; Reinoso, Alejandro; Velarde, Macarena; Valenzuela, María Teresa; Inostroza, Carolina

2017-01-01

The Adolescent Branch from Sociedad Chilena de Pediatría supports the implementation of planned programs for transition from child to adult health centers, oriented to adolescents with chronic diseases, in order to ensure an appropriate follow-up and a high-quality health care. Recommendations for care are set out in the FONIS and VRI PUC project carried out by the Division of Pediatrics of the Universidad Católica de Chile: “Transition process from pediatric to adult services: perspectives of adolescents with chronic diseases, caregivers and health professionals”, whose goal was to describe the experience, barriers, critical points, and facilitators in the transition process. Critical points detected in this study were: existence of a strong bond between adolescents, caregivers and the pediatric team, resistance to transition, difficulty developing autonomy and self-management among adolescents; invisibility of the process of adolescence; and lack of communication between pediatric and adult team during the transfer. According to these needs, barriers and critical points, and based on published international experiences, recommendations are made for implementation of gradual and planned transition processes, with emphasis on the design and implementation of transition policies, establishment of multidisciplinary teams and transition planning. We discuss aspects related to coordination of teams, transfer timing, self-care and autonomy, transition records, adolescent and family participation, need for emotional support, ethical aspects involved, importance of confidentiality, need for professional training, and the need for evaluation and further research on the subject.

Contaminación con bacterias patógenas de estetoscopios del personal médico en un hospital de nivel III en Lima, Perú

OpenAIRE

Oliva-Menacho, José Enrique; García-Hjarles, Marco Antonio; Oliva-Candela, José Arturo; De la Cruz-Roca, Hugo Saturnino

2016-01-01

Objetivos: Determinar el grado de contaminación bacteriana con bacterias patógenas de los estetoscopios del personal médico en un hospital general de Lima, Perú. Material y métodos: Estudio de tipo observacional, descriptivo y transversal, realizado en el Hospital Nacional Arzobispo Loayza, entre los meses de enero y juniodel 2013. Se estudiaron 124 muestras de estetoscopios del personal médico en las siguientes áreas: UCI 20; neonatología 13; quemados 3; medicina 52; emergencia 36. Se recole...

Headspace solid-phase microextraction (HS-SPME) combined with GC-MS as a process analytical technology (PAT) tool for monitoring the cultivation of C. tetani.

Science.gov (United States)

Ghader, Masoud; Shokoufi, Nader; Es-Haghi, Ali; Kargosha, Kazem

2018-04-15

Vaccine production is a biological process in which variation in time and output is inevitable. Thus, the application of Process Analytical Technologies (PAT) will be important in this regard. Headspace solid - phase microextraction (HS-SPME) coupled with GC-MS can be used as a PAT for process monitoring. This method is suitable to chemical profiling of volatile organic compounds (VOCs) emitted from microorganisms. Tetanus is a lethal disease caused by Clostridium tetani (C. tetani) bacterium and vaccination is an ultimate way to prevent this disease. In this paper, SPME fiber was used for the investigation of VOCs emerging from C. tetani during cultivation. Different types of VOCs such as sulfur-containing compounds were identified and some of them were selected as biomarkers for bioreactor monitoring during vaccine production. In the second step, the portable dynamic air sampling (PDAS) device was used as an interface for sampling VOCs by SPME fibers. The sampling procedure was optimized by face-centered central composite design (FC-CCD). The optimized sampling time and inlet gas flow rates were 10 min and 2 m L s -1 , respectively. PDAS was mounted in exhausted gas line of bioreactor and 42 samples of VOCs were prepared by SPME fibers in 7 days during incubation. Simultaneously, pH and optical density (OD) were evaluated to cultivation process which showed good correlations with the identified VOCs (>80%). This method could be used for VOCs sampling from off-gas of a bioreactor to monitoring of the cultivation process. Copyright © 2018. Published by Elsevier B.V.

An integrated process analytical technology (PAT) approach to monitoring the effect of supercooling on lyophilization product and process parameters of model monoclonal antibody formulations.

Science.gov (United States)

Awotwe Otoo, David; Agarabi, Cyrus; Khan, Mansoor A

2014-07-01

The aim of the present study was to apply an integrated process analytical technology (PAT) approach to control and monitor the effect of the degree of supercooling on critical process and product parameters of a lyophilization cycle. Two concentrations of a mAb formulation were used as models for lyophilization. ControLyo™ technology was applied to control the onset of ice nucleation, whereas tunable diode laser absorption spectroscopy (TDLAS) was utilized as a noninvasive tool for the inline monitoring of the water vapor concentration and vapor flow velocity in the spool during primary drying. The instantaneous measurements were then used to determine the effect of the degree of supercooling on critical process and product parameters. Controlled nucleation resulted in uniform nucleation at lower degrees of supercooling for both formulations, higher sublimation rates, lower mass transfer resistance, lower product temperatures at the sublimation interface, and shorter primary drying times compared with the conventional shelf-ramped freezing. Controlled nucleation also resulted in lyophilized cakes with more elegant and porous structure with no visible collapse or shrinkage, lower specific surface area, and shorter reconstitution times compared with the uncontrolled nucleation. Uncontrolled nucleation however resulted in lyophilized cakes with relatively lower residual moisture contents compared with controlled nucleation. TDLAS proved to be an efficient tool to determine the endpoint of primary drying. There was good agreement between data obtained from TDLAS-based measurements and SMART™ technology. ControLyo™ technology and TDLAS showed great potential as PAT tools to achieve enhanced process monitoring and control during lyophilization cycles. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

Field services experiences

International Nuclear Information System (INIS)

Colflesh, J.A.; Kruse, P.W.; Merluzzi, R.A.

1985-01-01

Combustion Engineering (C-E) is a large diversified manufacturer of products and services for the energy field. At this time, C-E has supplied the nuclear steam supply systems for eleven operating nuclear power plants with two additional units currently undergoing start-up testing. The focus of C-E's commitment in the nuclear power plant services area is the Nuclear Services organization within the Nuclear Power Systems Division. The Nuclear Services organization provides services on a timely cost efficient basis; and dedicates resources to developing new products and services which are truly responsive to the needs of operating power plants world wide. In the paper, C-E's capabilities and experience in the field of nuclear services are described. Highlighted are our capabilities in the areas of transition management services, operating services and engineering services

Integrating transition theory and bioecological theory: a theoretical perspective for nurses supporting the transition to adulthood for young people with medical complexity.

Science.gov (United States)

Joly, Elizabeth

2016-06-01

To present a discussion of a theoretical perspective developed through integrating Meleis' Transition Theory and Bronfenbrenner's Bioecological Theory of Human Development to inform nursing and advanced nursing practice supporting the transition to adulthood for young people with medical complexity. Theoretical perspectives to inform nursing practice in supporting successful transition are limited, yet nurses frequently encounter young people with medical complexity during the transition to adulthood. Discussion paper. A literature search of CINAHL and Medline was conducted in 2014 and included articles from 2003-2014; informal discussions with families; the author's experiences in a transition program. The integrated theoretical perspective described in this paper can inform nurses and advanced practice nurses on contextual influences, program and intervention development across spheres of influence and outcomes for the transition to adulthood for young people with medical complexity. Young people and their families require effective reciprocal interactions with individuals and services across sectors to successfully transition to adulthood and become situated in the adult world. Intervention must also extend beyond the young person to include providers, services and health and social policy. Nurses can take a leadership role in supporting the transition to adulthood for young people with medical complexity through direct care, case management, education and research. It is integral that nurses holistically consider developmental processes, complexity and contextual conditions that promote positive outcomes during and beyond the transition to adulthood. © 2016 John Wiley & Sons Ltd.

The Challenge of the GATS for Transition Economies Seeking to Join the WTO

Directory of Open Access Journals (Sweden)

J. Anthony VanDuzer

2004-02-01

Full Text Available Transition economies seeking to join the World Trade Organization (WTO face a variety of distinctive challenges relating to their prospective obligations under the General Agreement on Trade in Services (GATS. Transition economies are characterized by changing market and industry structures on the one hand, and ongoing reforms to their regulatory structures on the other. Both make it extremely difficult for transition economies to develop a position on what WTO services commitments they should undertake in their national schedules of specific commitments. Accession negotiations are further complicated by the evolving nature of GATS rules themselves and the tough negotiating stance taken by existing Members. Based on evidence from recent accessions, the effective minimum requirements relating to services for transition economies seeking to join the WTO are increasing

From admission to discharge in mental health services: a qualitative analysis of service user involvement.

Science.gov (United States)

Wright, Nicola; Rowley, Emma; Chopra, Arun; Gregoriou, Kyriakos; Waring, Justin

2016-04-01

User involvement and recovery are now widely used terms within the mental health policy, research and practice discourse. However, there is a question mark about the impact these ideas have in everyday practice. Of interest is the degree of involvement in key transitions of care. In particular, admission to and discharge from acute inpatient mental health wards. To explore the nature of service user involvement in the admission and discharge process into and out of acute inpatient mental health care. A qualitative study using focus groups. One acute, inpatient mental health ward was the focus of the study. Seven uniprofessional focus group interviews were conducted with ward staff, community staff and service users (total number of participants = 52). Conventional, thematic qualitative techniques were used to analyse the data. The data analysed and presented in this article relate to the loss of the service user voice at the key transition points into and out of acute inpatient care. Due to the lack of resources (inpatient beds and community care follow-up), the role service users could play was diminished. In their narratives, clinical staff associated the person with the process and used language which dehumanized the individual. Service users experience numerous care transitions into and out of hospital. As there is the potential for these encounters to have a lasting negative effect, the importance of ensuring service users have a voice in what is happening to them is crucial. © 2015 John Wiley & Sons Ltd.

Efficacy and Safety of Tranexamic Acid in Prehospital Traumatic Hemorrhagic Shock: Outcomes of the Cal-PAT Study

Directory of Open Access Journals (Sweden)

Michael M. Neeki

2017-04-01

Full Text Available Introduction: The California Prehospital Antifibrinolytic Therapy (Cal-PAT study seeks to assess the safety and impact on patient mortality of tranexamic acid (TXA administration in cases of trauma-induced hemorrhagic shock. The current study further aimed to assess the feasibility of prehospital TXA administration by paramedics within the framework of North American emergency medicine standards and protocols. Methods: This is an ongoing multi-centered, prospective, observational cohort study with a retrospective chart-review comparison. Trauma patients identified in the prehospital setting with signs of hemorrhagic shock by first responders were administered one gram of TXA followed by an optional second one-gram dose upon arrival to the hospital, if the patient still met inclusion criteria. Patients administered TXA make up the prehospital intervention group. Control group patients met the same inclusion criteria as TXA candidates and were matched with the prehospital intervention patients based on mechanism of injury, injury severity score, and age. The primary outcomes were mortality, measured at 24 hours, 48 hours, and 28 days. Secondary outcomes measured included the total blood products transfused and any known adverse events associated with TXA administration. Results: We included 128 patients in the prehospital intervention group and 125 in the control group. Although not statistically significant, the prehospital intervention group trended toward a lower 24-hour mortality rate (3.9% vs 7.2% for intervention and control, respectively, p=0.25, 48-hour mortality rate (6.3% vs 7.2% for intervention and control, respectively, p=0.76, and 28-day mortality rate (6.3% vs 10.4% for intervention and control, respectively, p=0.23. There was no significant difference observed in known adverse events associated with TXA administration in the prehospital intervention group and control group. A reduction in total blood product usage was observed

Alternativas tecnológicas aplicables al desarrollo y conservación de productos cárnicos cocidos (patés) durante el almacenamiento refrigerado

OpenAIRE

Terrasa, Ana María

2012-01-01

Teniendo en cuenta la relación existente entre nutrición y salud así como la demanda creciente de los consumidores de productos más saludables, en este trabajo de Tesis se han diseñado productos a base de hígado de pollo (patés o pastas de hígado) en los cuales se realizaron modificaciones de la fase grasa tanto cualitativas como cuantitativas. En ese sentido, en productos procesados elaborados con carne o vísceras, una de las estrategias utilizadas para la obtención de productos más saludabl...

Understanding social media program usage in public transit agencies

Directory of Open Access Journals (Sweden)

Jenny H. Liu

2016-10-01

Full Text Available Social media has been gaining prominence in public transit agencies in their communication strategies and daily management. This study aims to better understand recent trends in social media usage in public transit agencies, to examine which agencies use what kind of social media programs for what purposes, and how they measure their programs. A survey was conducted of the top transit agencies in the nation, and results are examined through descriptive statistical analysis, correlation analysis and regression modeling. We found that while most agencies still lack clearly-defined goals and performance metrics to guide their social media development, many are increasing their social media capacity with more structural components. Public transit service usage and the level of transit service provision are the most significant determinants of agencies’ social media programming and resource investments. In contrast, the measurement of social media usage and outcomes is more significantly related to city attributes and demographic characteristics. We anticipate an increase in the usage of social media to convey transit related stories and livability benefits, such as environmental sensitivity or safety improvements, as these programs expand. Public transit agencies’ commitment to measuring social media outcomes underscores the future research need to develop best practices for measuring the impacts and performance of social media communications and investments.

Fuel Cell Buses in U.S. Transit Fleets: Current Status 2010

Science.gov (United States)

2010-11-11

This past year has been one of transition for the introduction of fuel cell transit buses. The existing generation of fuel cell buses from Van Hool and UTC Power has continued to operate in service at three transit agencies. At the same time, a new g...

Public Transit Equity Analysis at Metropolitan and Local Scales: A Focus on Nine Large Cities in the US.

Science.gov (United States)

Griffin, Greg Phillip; Sener, Ipek Nese

2016-01-01

Recent studies on transit service through an equity lens have captured broad trends from the literature and national-level data or analyzed disaggregate data at the local level. This study integrates these methods by employing a geostatistical analysis of new transit access and income data compilations from the Environmental Protection Agency. By using a national data set, this study demonstrates a method for income-based transit equity analysis and provides results spanning nine large auto-oriented cities in the US. Results demonstrate variability among cities' transit services to low-income populations, with differing results when viewed at the regional and local levels. Regional-level analysis of transit service hides significant variation through spatial averaging, whereas the new data employed in this study demonstrates a block-group scale equity analysis that can be used on a national-scale data set. The methods used can be adapted for evaluation of transit and other modes' transportation service in areas to evaluate equity at the regional level and at the neighborhood scale while controlling for spatial autocorrelation. Transit service equity planning can be enhanced by employing local Moran's I to improve local analysis.

Etnicidad, actores y territorio : luchas de los afrodescendientes de Patía y el Valle del Chota por el acceso a tierra y agua, 1990-2010

OpenAIRE

Angulo Balanta, Diana Patricia

2013-01-01

Esta investigación trata de entender, desde el paradigma de la identidad, las transformaciones en los procesos organizativos y construcción identitarias de las poblaciones afrodescendientes del Patía y El Valle del Chota. Este análisis aborda la incursión de este grupo social en el campo político, para establecer ante el Estado y la sociedad reivindicaciones de carácter redistributivo y de reconocimiento, a partir de la construcción de significados. Lo anterior implica determinar los factores...

Implications of agricultural transitions and urbanization for ecosystem services.

Science.gov (United States)

Cumming, Graeme S; Buerkert, Andreas; Hoffmann, Ellen M; Schlecht, Eva; von Cramon-Taubadel, Stephan; Tscharntke, Teja

2014-11-06

Historically, farmers and hunter-gatherers relied directly on ecosystem services, which they both exploited and enjoyed. Urban populations still rely on ecosystems, but prioritize non-ecosystem services (socioeconomic). Population growth and densification increase the scale and change the nature of both ecosystem- and non-ecosystem-service supply and demand, weakening direct feedbacks between ecosystems and societies and potentially pushing social-ecological systems into traps that can lead to collapse. The interacting and mutually reinforcing processes of technological change, population growth and urbanization contribute to over-exploitation of ecosystems through complex feedbacks that have important implications for sustainable resource use.

PAT Design Strategy for Energy Recovery in Water Distribution Networks by Electrical Regulation

Directory of Open Access Journals (Sweden)

Helena M. Ramos

2013-01-01

Full Text Available In the management of water distribution networks, large energy savings can be yielded by exploiting the head drop due to the network pressure control strategy, i.e., for leak reductions. Hydropower in small streams is already exploited, but technical solutions combining efficiency and economic convenience are still required. In water distribution networks, an additional design problem comes out from the necessity of ensuring a required head drop under variable operating conditions, i.e., head and discharge variations. Both a hydraulic regulation (HR—via a series-parallel hydraulic circuit- and an electrical regulation (ER—via inverter- are feasible solutions. A design procedure for the selection of a production device in a series-parallel hydraulic circuit has been recently proposed. The procedure, named VOS (Variable Operating Strategy, is based on the overall plant efficiency criteria and is applied to a water distribution network where a PAT (pump as a turbine is used in order to produce energy. In the present paper the VOS design procedure has been extended to the electrical regulation and a comparison between HR and ER efficiency and flexibility within a water distribution network is shown: HR was found more flexible than ER and more efficient. Finally a preliminary economic study has been carried out in order to show the viability of both systems, and a shorter payback period of the electromechanical equipment was found for HR mode.

Comparison Between IPv4 to IPv6 Transition Techniques

OpenAIRE

Cordeiro, Edwin; Carnier, Rodrigo; Zucchi, Wagner L

2016-01-01

The IPv4 addresses exhaustion demands a protocol transition from IPv4 to IPv6. The original transition technique, the dual stack, is not widely deployed yet and it demanded the creation of new transition techniques to extend the transition period. This work makes an experimental comparison of techniques that use dual stack with a limited IPv4 address. This limited address might be a RFC 1918 address with a NAT at the Internet Service Provider (ISP) gateway, also known as Carrier Grade NAT (CG...

The Military and the Transition to Adulthood

Science.gov (United States)

Kelty, Ryan; Kleykamp, Meredith; Segal, David R.

2010-01-01

Ryan Kelty, Meredith Kleykamp, and David Segal examine the effect of military service on the transition to adulthood. They highlight changes since World War II in the role of the military in the lives of young adults, focusing especially on how the move from a conscription to an all-volunteer military has changed the way military service affects…

"Getting the Pieces Together": Negotiating the Transition from Pre-Service to In-Service Teacher

Science.gov (United States)

Pietsch, Marilyn; Williamson, John

2010-01-01

For beginning teachers to make the transition to full professional membership they need to increase their professional knowledge of the art and science of teaching. This paper explores the difference in knowledge growth between beginning teachers who commence teaching in fragmented teaching situations in the first two years of teaching, and their…

Transitioning to Government Shared Services Centres: A Systems View

DEFF Research Database (Denmark)

Tambo, Torben; Bækgaard, Lars

2014-01-01

. Services, however, tend to be more complex than the mere act of interaction or working process, and should be seen out of the cultural, organisational and managerial factors surrounding it. This chapter will use a service model consisting of execution, context and intention with an underlying claim...

77 FR 47692 - Notice of Transportation Services' Transition From Paper to Electronic Fare Media Comments...

Science.gov (United States)

2012-08-09

... and effective electronic fare media transition to its participating transit benefit agencies... New Program Distribution Methodology for Transit Benefits This section presents a summary of the..., 2012 on TRANServe's adoption of a new program distribution methodology for transit benefits and...

National Fuel Cell Bus Program : Accelerated Testing Report, AC Transit

Science.gov (United States)

2009-01-01

This is an evaluation of hydrogen fuel cell transit buses operating at AC Transit in revenue service since March 20, 2006 compared to similar diesel buses operating from the same depot. This evaluation report includes results from November 2007 throu...

The value of service reliability

OpenAIRE

Benezech , Vincent; Coulombel , Nicolas

2013-01-01

International audience; This paper studies the impact of service frequency and reliability on the choice of departure time and the travel cost of transit users. When the user has (α, β, γ) scheduling preferences, we show that the optimal head start decreases with service reliability, as expected. It does not necessarily decrease with service frequency, however. We derive the value of service headway (VoSH) and the value of service reliability (VoSR), which measure the marginal effect on the e...

From transmission to transition: lessons learnt from the Thai paediatric antiretroviral programme.

Directory of Open Access Journals (Sweden)

Olivia Tulloch

Full Text Available BACKGROUND: The Thai HIV programme is a leader in the public health approach to HIV treatment. Starting at transmission of HIV and ending with transition to adult services this paper assesses the paediatric HIV treatment continuum from three perspectives: service-user, provider and policy maker, to understand what works well and why. METHODS: A qualitative research design was used to assess and triangulate the stakeholder perspectives. Semi-structured interviews were conducted with ART service-users (n = 35, policy actors (n = 20; telephone interviews with prior caregivers of orphans (n = 10; and three focus group discussions with service-providers (hospital staff and volunteers from a district, provincial and a university hospital. FINDINGS: Children accessing HIV care were often orphaned, cared for by elderly relatives and experiencing multiple vulnerabilities. Services were divided into three stages, 1. Diagnosis and linkage: Despite strong policies there were supply and demand-side gaps in the prevention of mother-to-child transmission 'cascade' preventing early diagnosis and/or treatment. 2. Maintenance on ART - Children did well on treatment; caregivers took adherence seriously and valued the quality of services. Drug resistance, adherence and psychosocial issues were important concerns from all perspectives. 3. Adolescents and transition: Adolescent service-users faced greater complexity in their physical and emotional lives for which providers lacked skills; transition from the security of paediatric clinic was a daunting prospect. Dedicated healthcare providers felt they struggled to deliver services that met service-users' diverse needs at all stages. Child- and adolescent-specific elements of HIV policy were considered low priority. CONCLUSIONS: Using the notion of the continuum of care a number of strengths and weaknesses were identified. Features of paediatric services need to evolve alongside the changing needs of service users

Independent Living Transition Assistance for Young Adults Who Have Special Needs

Science.gov (United States)

Russell, Rhonda L.

2016-01-01

This research focused on young adults who have disabilities and their transition and career planning for post-secondary life. The study sought to identify best practices in transition planning, transition planning services, and to determine the types of resources and support needed by young adults who have disabilities. For youth who have…

A Performance Prediction Method for Pumps as Turbines (PAT Using a Computational Fluid Dynamics (CFD Modeling Approach

Directory of Open Access Journals (Sweden)

Emma Frosina

2017-01-01

Full Text Available Small and micro hydropower systems represent an attractive solution for generating electricity at low cost and with low environmental impact. The pump-as-turbine (PAT approach has promise in this application due to its low purchase and maintenance costs. In this paper, a new method to predict the inverse characteristic of industrial centrifugal pumps is presented. This method is based on results of simulations performed with commercial three-dimensional Computational Fluid Dynamics (CFD software. Model results have been first validated in pumping mode using data supplied by pump manufacturers. Then, the results have been compared to experimental data for a pump running in reverse. Experimentation has been performed on a dedicated test bench installed in the Department of Civil Construction and Environmental Engineering of the University of Naples Federico II. Three different pumps, with different specific speeds, have been analyzed. Using the model results, the inverse characteristic and the best efficiency point have been evaluated. Finally, results have been compared to prediction methods available in the literature.

A PAT approach for the on-line monitoring of pharmaceutical co-crystals formation with near infrared spectroscopy.

Science.gov (United States)

Sarraguça, Mafalda C; Ribeiro, Paulo R S; Santos, Adenilson O; Silva, Marta C D; Lopes, João A

2014-08-25

Cocrystals represent a class of crystalline solids consisting of two or more molecular species usually held together by non-covalent bonds. Pharmaceutical cocrystals can alter the physicochemical properties of the active pharmaceutical ingredient to improve solubility, dissolution rate, particle properties and stability. This work presents a process analytical technology (PAT) approach to monitor on-line the cocrystallization of furosemide and adenine by solvent evaporation using near infrared spectroscopy (NIRS). Furosemide and adenine were added to a small volume of methanol in a beaker and stirred on an orbital stirring table during 8h at room temperature. The on-line monitoring was performed with a FT-NIR spectrometer fitted with a reflectance fiber optic probe. Monitoring was performed with the probe tip placed 1cm above the cocrystallization medium to avoid interference with the cocrystallization process. Cocrystals were vacuum dried to remove residual solvent and characterized off-line by NIRS, MIRS, DSC and XRPD. Results demonstrate that it was possible to follow the main cocrystallization events on-line. Copyright © 2014 Elsevier B.V. All rights reserved.

Are family-centred principles, functional goal setting and transition planning evident in therapy services for children with cerebral palsy?

Science.gov (United States)

Darrah, J; Wiart, L; Magill-Evans, J; Ray, L; Andersen, J

2012-01-01

Family-centred service, functional goal setting and co-ordination of a child's move between programmes are important concepts of rehabilitation services for children with cerebral palsy identified in the literature. We examined whether these three concepts could be objectively identified in programmes providing services to children with cerebral palsy in Alberta, Canada. Programme managers (n= 37) and occupational and physical therapists (n= 54) representing 59 programmes participated in individual 1-h semi-structured interviews. Thirty-nine parents participated in eleven focus groups or two individual interviews. Evidence of family-centred values in mission statements and advisory boards was evaluated. Therapists were asked to identify three concepts of family-centred service and to complete the Measures of Process of Care for Service Providers. Therapists also identified therapy goals for children based on clinical case scenarios. The goals were coded using the components of the International Classification of Functioning Disability and Health. Programme managers and therapists discussed the processes in their programmes for goal setting and for preparing children and their families for their transition to other programmes. Parents reflected on their experiences with their child's rehabilitation related to family-centredness, goal setting and co-ordination between programmes. All respondents expressed commitment to the three concepts, but objective indicators of family-centred processes were lacking in many programmes. In most programmes, the processes to implement the three concepts were informal rather than standardized. Both families and therapists reported limited access to general information regarding community supports. Lack of formal processes for delivery of family-centred service, goal-setting and co-ordination between children's programmes may result in inequitable opportunities for families to participate in their children's rehabilitation despite

Sound transit climate risk reduction project.

Science.gov (United States)

2013-09-01

The Climate Risk Reduction Project assessed how climate change may affect Sound Transit commuter rail, light rail, and express bus : services. The project identified potential climate change impacts on agency operations, assets, and long-term plannin...

Office of Special Services Annual Report, FY 1999.

Science.gov (United States)

Front Range Community Coll., Westminster, CO.

This report lists support services provided by the Westminster Campus Special Services Department to the Westminster, Brighton, Longmont, and North Boulder Campuses. The Special Services Department provides disability services, including interpreting for the deaf, tutoring, gender equity support, and special populations transition support.…

Smart Location Database - Service

Data.gov (United States)

U.S. Environmental Protection Agency — The Smart Location Database (SLD) summarizes over 80 demographic, built environment, transit service, and destination accessibility attributes for every census block...

Estudio geoeléctrico en el valle alto del Rio Patía

Directory of Open Access Journals (Sweden)

Pérez Cerón Rosalbina

1995-10-01

Full Text Available

The resistivity survey carried out at the upper valley of the Patía River, provided good information to define the sedimentary sequence of the area. A general sequence from top to base is described as follows: recent deposits with resistivity values between 20 and 400 Ohrn-m, fine to medium grain, sandstones with resistivity values between 20 and 70 Ohrn-m, fine grain sandstones and silstones with resistivity values between 8 and 20 Ohrn-rn, and clayli basement, with resistivity less than 20 Ohm-m. There are two kinds of aquifers; free, related to sands and gravels from alluvial fans and terraces (resistivity values between 70 and 400 Ohrn-m and thickness between 25 and 75, semi-confined related to tertiary sandstones (resistivities values between 20 and 30 Ohm-m, thickness between 35 and 150 m. The water quality of the upper aquifers is good enough with small amounts of salt content. Saline water is found at the lower aquifer.

The resistivity method was useful to locate geological discontinuities; some of them found with surface expression associated with lineaments and faults. Some of these geological features have been mapped in previous geological works on the area. In general the interpretation based on the resistivity results shows a block tectonics environment affecting cretaceous and tertiary rocks and probably the quaternary deposit.

Transition and Students with Mild Intellectual Disability: Findings From the National Longitudinal Transition Study-2

Science.gov (United States)

Bouck, Emily C.; Joshi, Gauri S.

2016-01-01

Students with intellectual disability historically struggle with post-school outcomes. However, much of the research on students with intellectual disability relative to post-school outcomes and transition services is aggregated for students with mild, moderate, and severe intellectual disability. This secondary analysis of the National…

125I-BH-8-MeO-N-PAT, a new ligand for studying 5-HT1A receptors in the central nervous system

International Nuclear Information System (INIS)

Ponchant, M.; Beaucourt, J.P.; Vanhove, A.

1988-01-01

Specific radioactive ligands are needed for studying the pharmacological properties and the regional distribution of the different classes of 5-HT 1 receptors within the central nervous system. We describe here the synthesis and some characteristics of the first iodinated specific ligand of 5-HT 1A receptors. Like its parent compound, the agonist 8-hydroxy-2-(di-n-propylamino)tetralin or 8-OH-DPAT, [ 125 I]-BH-8-MeO-N-PAT, exhibits a high affinity and excellent selectivity for 5-HT 1A sites. Its high specific radioactivity makes this ligand a useful tool for studying 5-HT 1A receptors in membranes and sections of the rat brain [fr

Estimating and Enhancing Public Transit Accessibility for People with Mobility Limitations

Science.gov (United States)

2017-06-30

This two-part study employs fine-scale performance measures and analytical techniques designed to evaluate and improve transit services for people experiencing disability. Part one puts forth a series of time-sensitive, general transit feed system (G...

Service quality attributes affecting passengers' satisfaction with ...

African Journals Online (AJOL)

Service quality and customer satisfaction are the growing concerns for business organizations throughout the world, and customer satisfaction studies have been proven to be essential tools in trying to optimize services provided to users. For transit agencies, as in other service industries, increase in customer satisfaction ...

Transition for Teenagers with Intellectual Disability: Carers' Perspectives

Science.gov (United States)

Bhaumik, Sabyasachi; Watson, Joanna; Barrett, Mary; Raju, Bala; Burton, Tracey; Forte, Jane

2011-01-01

Teenagers with intellectual disabilities (ID) have significantly more health problems than the rest of the population and many encounter difficulties accessing the services they need during the transition from children's to adult services. A multidisciplinary, interagency study was carried out in one area of the UK with the intent to estimate the…

Presencia de sistemas de secreción de patógenos en bacterias endosimbióticas aisladas de Lupinus de la península Ibérica

OpenAIRE

Pastor, Víctor; Iglesias, Ana Isabel; Duran Wendt, David Ricardo; Rey Navarro, Luis

2012-01-01

Los rizobios son bacterias endosimbióticas capaces de fijar nitrógeno en estructuras especializadas de leguminosas. Esta simbiosis es altamente específica y depende, entre otros factores, de la capacidad de los rizobios de secretar proteínas efectoras a las células vegetales. Se han descrito diferentes sistemas de secreción en patógenos animales y vegetales y posteriormente también se han encontrado en algunos rizobios. En este trabajo se presenta el estudio de varios sistemas de secreción id...

Structured Transition Protocol for Children with Cystinosis

Directory of Open Access Journals (Sweden)

Rupesh Raina

2017-08-01

Full Text Available The transition from pediatric to adult medical services has a greater impact on the care of adolescents or young adults with chronic diseases such as cystinosis. This transition period is a time of psychosocial development and new responsibilities placing these patients at increased risk of non-adherence. This can lead to serious adverse effects such as graft loss and progression of the disease. Our transition protocol will provide patients, families, physicians, and all those involved a structured guide to transitioning cystinosis patients. This structured protocol depends on four areas of competency: Recognition, Insight, Self-reliance, and Establishment of healthy habits (RISE. This protocol has not been tested and therefore challenges not realized. With a focus on medical, social, and educational/vocational aspects, we aim to improve transition for cystinosis patients in all aspects of their lives.

Total filmless digital radiology service

International Nuclear Information System (INIS)

Mun, S.K.; Goeringer, F.; Benson, H.; Horii, S.C.

1989-01-01

The completion of a comprehensive picture archiving and communication system (PACS) at Georgetown University Hospital has allowed us to identify a number of technical, administrative, personnel, and operational issues that will affect a total digital radiology service. With a hospital-wide digital imaging network system, computer simulation of communications and storage options, and economic modeling, we have developed a feasibility study and implementation strategy for the smooth transition to a nearly filmless radiology service over the next several years. This paper describes the technical and operational requirements for various database operations, workstations (used in diagnosis, review, and education), and communications. Site and installation planning, personnel training, and transition operations are discussed

Modeling and evaluation of characteristics for on-street Rapid Transit systems

DEFF Research Database (Denmark)

Andersen, Jonas Lohmann Elkjær; Landex, Alex

2012-01-01

to obtain the main objective of introducing a Rapid Transit System. to increase the number of passengers. Variations in the system characteristics have a direct impact on ridership. However, it is difficult to predict the impact of implementing or altering the characteristics. A Rapid Transit system should...... display sufficient service already in the planning phase. That is why pre-acquired knowledge of the impact of the characteristics on the system performance is valuable. Such knowledge could provide a firm basis for planning the service and operation of a Rapid Transit system. This article focuses....... It focuses on the following characteristics for Rapid Transit systems: rail factor, travel time, headway and capacity. It evaluates how the implementation and variation of these characteristics affected the ridership of a case project. It evaluates the magnitude of the impacts for the various characteristics...

Improved methods for operating public transportation services.

Science.gov (United States)

2013-03-01

In this joint project, West Virginia University and the University of Maryland collaborated in developing improved methods for analyzing and managing public transportation services. Transit travel time data were collected using GPS tracking services ...

Veterans' Transitions to Community College: A Case Study

Science.gov (United States)

Wheeler, Holly A.

2012-01-01

Veterans on college campuses are not new; however, the recent influx of veterans returning home from war-time service present challenges to the colleges they attend. The purpose of this qualitative case study was to examine the transition process experienced by veterans leaving military service and attending community college for the first time.…

Exclusive queueing model including the choice of service windows

Science.gov (United States)

Tanaka, Masahiro; Yanagisawa, Daichi; Nishinari, Katsuhiro

2018-01-01

In a queueing system involving multiple service windows, choice behavior is a significant concern. This paper incorporates the choice of service windows into a queueing model with a floor represented by discrete cells. We contrived a logit-based choice algorithm for agents considering the numbers of agents and the distances to all service windows. Simulations were conducted with various parameters of agent choice preference for these two elements and for different floor configurations, including the floor length and the number of service windows. We investigated the model from the viewpoint of transit times and entrance block rates. The influences of the parameters on these factors were surveyed in detail and we determined that there are optimum floor lengths that minimize the transit times. In addition, we observed that the transit times were determined almost entirely by the entrance block rates. The results of the presented model are relevant to understanding queueing systems including the choice of service windows and can be employed to optimize facility design and floor management.

Análisis proteómico de la resistencia inducida por micorrización al patógeno foliar Sclerotinia sclerotiorum en frijol (Phaseolus vulgaris l.)

OpenAIRE

Quintero Zamora, Edalhí

2014-01-01

En los últimos años se han reportado diversos estudios sobre la resistencia inducida por micorrización al ataque de patógenos, en éstos se han determinado los cambios de expresión de genes y proteínas que ocurren en las raíces de plantas colonizadas por hongos micorrízicos arbusculares. Recientemente, se han iniciado estudios para entender cómo afecta esta interacción a la parte aérea de la planta. En nuestro grupo de investigación se llevó a cabo el estudio del efecto de la micorrizaci...

Services Supporting the Customer

DEFF Research Database (Denmark)

Gremyr, Ida; Halldorsson, Arni; Hsuan, Juliana

2017-01-01

This paper focuses on customer and user experience of advanced service offerings, focusing mechanisms such as e.g. feedback processes as a means to utilise and learn from users’ experiences. The purpose is to understand how servitization changes the constellation of actors in aftermarket value...... creation, and what mechanisms are needed for firms to exploit the interactions in these new constellation as a basis for service improvement and development. By studying two manufacturing firms offering advanced services, this paper points to changed actor configurations (both intra- and inter......-organisational) and interaction mechanisms (existing and new) when transitioning to offering more advanced services such as “services supporting customers”....

Thailand's Work and Health Transition.

Science.gov (United States)

Kelly, Matthew; Strazdins, Lyndall; Dellora, Tarie; Khamman, Suwanee; Seubsman, Sam-Ang; Sleigh, Adrian C

2010-09-01

Thailand has experienced a rapid economic transition from agriculture to industry and services, and from informal to formal employment. It has much less state regulation and worker representation relative to developed nations, who underwent these transitions more slowly and sequentially, decades earlier. We examine the strengthening of Thai government policy and legislation affecting worker's health, responding to international norms, a new democratic constitution, fear of foreign importer embargos and several fatal workplace disasters. We identify key challenges remaining for Thai policy makers, including legislation enforcement and the measurement of impacts on worker's mental and physical health.

Port Authority of Allegheny County Transit Stops

Data.gov (United States)

Allegheny County / City of Pittsburgh / Western PA Regional Data Center — All transit stops within the Port Authority of Allegheny County's service area for the November 20, 2016 - March (TBD) 2017 schedule period.

Performance measures for public transit mobility management.

Science.gov (United States)

2011-12-01

"Mobility management is an innovative approach for managing and delivering coordinated public : transportation services that embraces the full family of public transit options. At a national level, there are : currently no industry recognized perform...

Employment outcomes of transition-aged adults with autism spectrum disorders: a state of the States report.

Science.gov (United States)

Burgess, Sloane; Cimera, Robert E

2014-01-01

The primary purpose of this study was to evaluate the employment outcomes of transition-aged adults with autism spectrum disorders (ASD) served by vocational rehabilitation services (VR) over the last 10 years by state. A secondary purpose was to compare employment outcomes of individuals with ASD to those of the overall transition-aged population served by VR for the same time period. Although there was variability both within and among states, the results of this study indicate that, over time, the number of young adults with ASD seeking VR services has increased; however, employment outcomes including the percent of adults with ASD achieving employment, the number of hours worked, and wages earned have not improved for this group. The cost to provide VR services to transition-aged adults with ASD was relatively stable over time. Transition-aged adults with ASD were more likely to become successfully employed as a result of receiving VR services than the overall population of transition-aged adults served by VR. However, the employed transition-aged adults consistently worked fewer hours and earned lower wages than those in the overall population. Factors that may influence variability within and among states, and between groups, and implications for research and practice are discussed.

Stakeholder Perspectives on Research and Practice in Autism and Transition.

Science.gov (United States)

Kuo, Alice A; Crapnell, Tara; Lau, Lynette; Anderson, Kristy A; Shattuck, Paul

2018-04-01

Individuals with autism spectrum disorder (ASD) are reported to experience significant challenges during the transition to adulthood. Although recent evidence indicates that individuals with ASD experience poor outcomes in adulthood, little is understood about the contributing factors. In this qualitative study, we investigated the barriers to and needs in research and practice in the transition to adulthood among individuals with ASD. Thirteen researchers, including service providers, family members, and an individual with ASD participated in 30- to 60-minute, semistructured, open-ended telephone interviews. Interviews were transcribed, and data were analyzed by using an inductive approach to identify themes related to barriers to and needs in the transition to adulthood for youth with ASD. Stakeholders identified the need for transition planning and preparation to begin earlier and for systems to better accommodate the interests and varying abilities of individuals with ASD. Stakeholders also felt that parent and service provider expectations and perceptions influence early opportunities and experiences offered throughout the transition process. This study reveals the multilevel barriers to and needs in the transition to adulthood and the need for interagency and multidisciplinary collaboration and research to address the varying levels of needs, abilities, and multisector challenges. Copyright © 2018 by the American Academy of Pediatrics.

Transitioning Adolescents and Young Adults With HIV Infection to Adult Care: Pilot Testing the "Movin' Out" Transitioning Protocol.

Science.gov (United States)

Maturo, Donna; Powell, Alexis; Major-Wilson, Hannah; Sanchez, Kenia; De Santis, Joseph P; Friedman, Lawrence B

2015-01-01

Advances in care and treatment of adolescents/young adults with HIV infection have made survival into adulthood possible, requiring transition to adult care. Researchers have documented that the transition process is challenging for adolescents/young adults. To ensure successful transition, a formal transition protocol is needed. Despite existing research, little quantitative evaluation of the transition process has been conducted. The purpose of the study was to pilot test the "Movin' Out" Transitioning Protocol, a formalized protocol developed to assist transition to adult care. A retrospective medical/nursing record review was conducted with 38 clients enrolled in the "Movin' Out" Transitioning Protocol at a university-based adolescent medicine clinic providing care to adolescents/young adults with HIV infection. Almost half of the participants were able to successfully transition to adult care. Reasons for failure to transition included relocation, attrition, lost to follow-up, and transfer to another adult service. Failure to transition to adult care was not related to adherence issues, X(2) (1, N=38)=2.49, p=.288; substance use, X(2) (1, N=38)=1.71, p=.474; mental health issues, X(2) (1, N=38)=2.23, p=.322; or pregnancy/childrearing, X(2) (1, N=38)=0.00, p=.627). Despite the small sample size, the "Movin' Out" Transitioning Protocol appears to be useful in guiding the transition process of adolescents/young adults with HIV infection to adult care. More research is needed with a larger sample to fully evaluate the "Movin' Out" Transitioning Protocol. Copyright © 2015 Elsevier Inc. All rights reserved.

Detroit regional transit legal structures and governance.

Science.gov (United States)

2014-03-01

Effective governance of transit systems is created through a qualified, representative, informed, diverse, and committed board of : directors that is ultimately accountable for the financial performance and quality of the service in the designated re...

The Evolution of the Shared Services Business Unit.

Science.gov (United States)

Forst, Leland

2000-01-01

Explains shared services, where common business practices are applied by a staff unit focused entirely on delivering needed services at the highest value and lowest cost to internal customers. Highlights include accountability; examples of pioneering shared services organizations; customer focus transition; relationship management; expertise…

The OPECST and the energy transition

International Nuclear Information System (INIS)

Le Deaut, Jean-Yves

2014-01-01

The OPECST is the French Parliamentary Office of Assessment of Scientific and Technological Choices. It has been created in 1983. Its activities and operational modality are presented. The next part comments OPECST activities related to energy transition, evokes some reports published on different topics: the future of the nuclear sector, the perspectives of non conventional hydrocarbons, the possibilities of the use of hydrogen for energy storage. Several aspects are notably addressed: the technical conditions to be met for a successful energy transition, the role of nuclear energy in energy transition, the extension of nuclear reactor service lifetime, the opinion of the OPECST on some prospective scenarios (ADEME and Negawatt). The improvement of buildings thermal insulation is commented as a major element in energy transition, but the complexity of regulations and problems for investors are outlined, as well as the cost of renovation for households

Review on Malaysian Rail Transit Operation and Management System: Issues and Solution in Integration

Science.gov (United States)

Masirin, Mohd Idrus Mohd; Salin, Aminah Mohd; Zainorabidin, Adnan; Martin, David; Samsuddin, Norshakina

2017-08-01

In any context, operation and management of transportation systems are key issues which may affect both life quality and economic development. In large urban agglomerations, an efficient public transportation system may help abate the negative externalities of private car use such as congestion, air and noise pollution, accident and fuel consumption, without excessively penalizing user travel times or zone accessibility. Thus, this study is conducted to appraise the Malaysian rural rail transit operation and management system, which are considered important as there are many issues and solution in integration of the services that need to be tackled more conscientiously. The purpose of this paper is to describe some of the most important issues on integration of services and rail transit system in Malaysian and how to solve or reduce these problems and conflicts. In this paper, it consists of the historical development of rail transit construction in Malaysia. This paper also attempts to identify the important issues related to rail transit services and integration in Malaysian rural rail operation and management system. Comparison is also conducted with other countries such as UK, France, and Japan. Finally, a critical analysis is presented in this paper by looking at the possible application for future Malaysian rail transit operation system and management, especially focusing on enhancing the quality of Malaysian rural rail transit. In conclusion, this paper is expected to successfully review and appraise the existing Malaysian rural rail transit operation and management system pertaining to issues & solution in integration. It is also hoped that reformation or transformation of present service delivery quality of the rail transit operation and management will enable Malaysia to succeed in transforming Malaysian transportation system to greater heights.

Using the ICF in transition research and practice? Lessons from a scoping review.

Science.gov (United States)

Nguyen, Tram; Stewart, Debra; Rosenbaum, Peter; Baptiste, Sue; Kraus de Camargo, Olaf; Gorter, Jan Willem

2018-01-01

The International Classification of Functioning, Disability and Health (ICF) and subsequent ICF-CY (child and youth version) recognize the importance of personal and environmental factors in facilitating holistic transition planning and service delivery for youth with chronic health conditions (YCHC). The objective of this scoping review is to investigate the degree to which the ICF and ICF-CY have been used in transition research and practice since its initial publication. Arksey and O'Malley's five-stage methodological framework guided the scoping review using the following databases: AMED, CINAHL, EMBASE, HealthSTAR, MEDLINE, and PsycINFO. Keywords included: 'ICF', 'ICF-CY', and 'transition', which were adapted to each database. 25 articles met final inclusion. Two key themes emerged regarding use of the ICF: 1) the ICF enhances transdisciplinary processes to inform transition planning and interventions; and 2) the ICF facilitates comprehensive and developmentally appropriate transition services over a youth's lifecourse. The strengths and limitations of the ICF in guiding the planning and delivery of transition services are discussed. Some limitations include the large number of items inherent within the ICF and a lack of clarity between the components of activity and participation. Key recommendations include: i) further explanation and development of items for quality of life and well-being, personal factors, and psychological issues; and ii) additional research to advance knowledge towards developing empirically- based evidence for the application of the ICF in clinical practice to facilitate transition. Copyright © 2017 Elsevier Ltd. All rights reserved.

Raman spectroscopy as a PAT for pharmaceutical blending: Advantages and disadvantages.

Science.gov (United States)

Riolo, Daniela; Piazza, Alessandro; Cottini, Ciro; Serafini, Margherita; Lutero, Emilio; Cuoghi, Erika; Gasparini, Lorena; Botturi, Debora; Marino, Iari Gabriel; Aliatis, Irene; Bersani, Danilo; Lottici, Pier Paolo

2018-02-05

Raman spectroscopy has been positively evaluated as a tool for the in-line and real-time monitoring of powder blending processes and it has been proved to be effective in the determination of the endpoint of the mixing, showing its potential role as process analytical technology (PAT). The aim of this study is to show advantages and disadvantages of Raman spectroscopy with respect to the most traditional HPLC analysis. The spectroscopic results, obtained directly on raw powders, sampled from a two-axis blender in real case conditions, were compared with the chromatographic data obtained on the same samples. The formulation blend used for the experiment consists of active pharmaceutical ingredient (API, concentrations 6.0% and 0.5%), lactose and magnesium stearate (as excipients). The first step of the monitoring process was selecting the appropriate wavenumber region where the Raman signal of API is maximal and interference from the spectral features of excipients is minimal. Blend profiles were created by plotting the area ratios of the Raman peak of API (A API ) at 1598cm -1 and the Raman bands of excipients (A EXC ), in the spectral range between 1560 and 1630cm -1 , as a function of mixing time: the API content can be considered homogeneous when the time-dependent dispersion of the area ratio is minimized. In order to achieve a representative sampling with Raman spectroscopy, each sample was mapped in a motorized XY stage by a defocused laser beam of a micro-Raman apparatus. Good correlation between the two techniques has been found only for the composition at 6.0% (w/w). However, standard deviation analysis, applied to both HPLC and Raman data, showed that Raman results are more substantial than HPLC ones, since Raman spectroscopy enables generating data rich blend profiles. In addition, the relative standard deviation calculated from a single map (30 points) turned out to be representative of the degree of homogeneity for that blend time. Copyright © 2017

Improving Access to Transit Through Crowdsourced Information

Science.gov (United States)

2017-11-01

The purpose of this research was to facilitate the ongoing collection of information from the public about potential areas of multimodal service and infrastructure improvements and easily share these problems with transit agencies, departments of tra...

Investigating Trauma in Narrating World War I: A Psychoanalytical Reading of Pat Barker’s Regeneration

Directory of Open Access Journals (Sweden)

Bakhtiar Sadjadi

2016-12-01

Full Text Available The present paper seeks to critically read Pat Barker’s Regeneration in terms of Cathy Caruth’s psychoanalytic study of trauma. This analysis attempts to trace the concepts of latency, post-traumatic stress disorders, traumatic memory, and trauma in Barker’s novel in order to explore how trauma and history are interrelated in the narrative of past history and, particularly, in the history of World War I. The present paper also demonstrates how Barker’s novel Regeneration acts as the narrative of trauma that vocalizes the silenced history of shell-shocked soldiers of World War I to represent British society, the history that has been concealed due to social and individual factors. The study thus investigates the dissociative disorders which are experienced by traumatized survivors of World War I as the aftermath of traumatic experiences of wartime. In addition, it argues how time moves for the traumatized victim and how the notion of latency in terms of Caruth’s theory is traceable in Barker’s novel. In Regeneration, the traumatized survivors are haunted with traumatic memory of past history; furthermore, past history constantly disrupts their present and the victims are in continuous shift from present time to past time. Time thus loses its linearity in the narrative of traumatized survivors. Keywords: Latency, post-traumatic stress disorders, traumatic memory, trauma

An Assessment of Future Demands for and Benefits of Public Transit Srevices in Tennessee

Energy Technology Data Exchange (ETDEWEB)

Southworth, F.

2004-04-29

This report documents results from a study carried out by Oak Ridge National Laboratory and the University of Tennessee at Knoxville for the Office of Public Transportation, Tennessee Department of Transportation. The study team was tasked with developing a process and a supporting methodology for estimating the benefits accruing to the State from the operation of state supported public transit services. The team was also tasked with developing forecasts of the future demands for these State supported transit services at five year intervals through the year 2020, broken down where possible to the local transit system level. Separate ridership benefits and forecasts were also requested for the State's urban and rural transit operations. Tennessee's public transit systems are subsidized to a degree by taxpayers. It is therefore in the public interest that assessments of the benefits of such systems be carried out at intervals, to determine how they are contributing to the well-being of the state's population. For some population groups within the State of Tennessee these transit services have become essential as a means of gaining access to workplaces and job training centers, to educational and health care facilities, as well as to shops, social functions and recreational sites.

Healthcare facility commissioning – the transition of clinical services

CSIR Research Space (South Africa)

Van der Watt, R

2016-07-01

Full Text Available structure of bricks and mortar into a functional facility with staff, equipment, medication, supplies, etc. ready to eventually receive patients who need care and cure. Beyond these tangible elements, there are also many intangibles which are required, e... in order for the new facility to deliver the intended clinical services. These include links to the emergency services which brings patients in need of emergency care to the facility, links to other healthcare facilities for more specialized care...

Korporatīvā sociālā atbildība: patērētāju uztveres un korporāciju komunikācijas analīze starptautiskajos tirgos uz McDonald's un Coca-Cola piemēra.

OpenAIRE

Teterins, Pāvels

2016-01-01

Korporatīvās sociālās atbildības (KSA) komunikācijas efektivitātes pamats ir pielāgošanās patērētāju prasībām. Pētījuma mērķis bija uz McDonald’s un Coca-Cola sociālo tīklu KSA komunikācijas piemēra, izvērtēt to, vai kompānijas pielāgo KSA komunikāciju patērētāju vērtējumam par atbildīgu uzņēmējdarbību, un piedāvāt optimālu KSA komunikācijas struktūru. Demogrāfisko faktoru ietekme uz Latvijas, Vācijas un Austrālijas KSA vērtējumu praktiski netika novērota. Savukārt, salīdzinot valstis savā st...

Parásitos patógenos en arena de playa y su relación con condiciones ambientales, en un balneario de Puerto Cabello, Venezuela, 2012-2013

OpenAIRE

Guerrero De Abreu, Arli Marlinet; Quiñones O, María Virginia; Sequera P, Ernesto José; Marín Franco, José Luis

2014-01-01

Venezuela, presenta una gran variedad de playas frecuentadas durante todo el año, por lo que legalmente se establece un monitoreo permanente de niveles de contaminación para su clasificación "apta" o no para bañistas. Sin embargo, esto no contempla la evaluación parasitológica en la arena de playa como criterio para la referida clasificación. Por ello, la presencia de sólo una forma parasitaria patógena indica que existe contaminación fecal dado por personas, animales o acúmulo de basura a lo...

Energy transitions research: Insights and cautionary tales

International Nuclear Information System (INIS)

Grubler, Arnulf

2012-01-01

This short essay first reviews the pioneers of energy transition research both in terms of data as well as theories. Three major insights that have emerged from this nascent research fields are summarized highlighting the importance of energy end-use and services, the lengthy process of transitions, as well as the patterns that characterize successful scale up of technologies and industries that drive historical energy transitions. The essay concludes with cautionary notes also derived from historical experience. In order to trigger a next energy transition policies and innovation efforts need to be persistent and continuous, aligned, as well as balanced. It is argued that current policy frameworks in place invariably do not meet these criteria and need to change in order to successfully trigger a next energy transition towards sustainability. - Highlights: ► Includes the first literature review of early energy transition research. ► Summarizes three major research findings from the literature. ► Reviews policy implications of recent case studies of energy technology innovation. ► Argues that current policy frameworks are deficient in view of above lessons.

STATEWIDE DATA STANDARDS TO SUPPORT CURRENT AND FUTURE STRATEGIC PUBLIC TRANSIT INVESTMENT

Science.gov (United States)

2018-04-01

Significant progress has been made in recent years in reporting and using public transit service data. With the creation and widespread use of the General Transit Feed Specification (GTFS) data standard, there has been a significant increase in the f...

Supporting graduate nurse transition to practice through a quality assurance feedback loop.

Science.gov (United States)

Phillips, Craig; Kenny, Amanda; Esterman, Adrian

2017-11-01

This mixed-method study focused on new graduate nurses and their transition to practice. Transition to practice can be a time of heightened stress and anxiety, leaving many new graduates disillusioned and dissatisfied with their work. The study explored how satisfaction levels with transition may improve during their first year, using a unique approach of a continuous quality assurance feedback loop. This assurance framework is utilised in hospitality, automotive and supply chain logistics and in health, primarily to monitor patient outcomes. However, an association with graduate nurse satisfaction has not been previously reported. Graduate nurses from two health services completed a short survey questionnaire every four weeks for 12 months. De-identified aggregated data was sent to health service management, giving them an opportunity to integrate the findings with the objective of potentially increasing graduate satisfaction ratings. Quantitative findings showed no statistical significance of graduate nurse satisfaction scores between health services, however, one health service consistently outperformed the other. Qualitative findings drawn from a seminar and interviews confirmed that one health service took a more proactive stance with the monthly reports, communicating the results to ward managers. Outcomes reflected a greater commitment of support and an overall increase of satisfaction scores. Copyright © 2017 Elsevier Ltd. All rights reserved.

Biodiesel fuel management best practices for transit

Science.gov (United States)

2007-11-27

Public transportation systems play a key role throughout the country not only in providing vital services to citizens but also in the environmental quality of our communities. Transit systems nationwide are seeking out new technologies in order to in...

A multicenter prospective quasi-experimental study on the impact of a transition-oriented generic patient education program on health service participation and quality of life in adolescents and young adults.

Science.gov (United States)

Schmidt, Silke; Herrmann-Garitz, Carsten; Bomba, Franziska; Thyen, Ute

2016-03-01

The aim of the study was to test the effects of a generic transition-oriented patient education program on adolescents' health service participation and quality of life (QoL). We conducted a controlled trial comparing participants of 29 transition workshops with treatment as usual in 274 adolescents (16.8 mean age, SD=1.76) diagnosed with type I diabetes (DM), cystic fibrosis (CF) or inflammatory bowel disease (IBD). A two-day transition workshop was carried out at 12 sites in Germany, focusing in standardized modules on adjustment to adult care settings, organization of future disease management, career choices and partnership. Study outcomes were health-related transition competence, self-efficacy, satisfaction with care, patient activation and QoL. Measures were assessed at baseline and six-month follow-up. Repeated-measurement covariance analysis using age as a covariate showed that the transition workshop significantly affected transition competence, self-efficacy and satisfaction with school care six months post intervention. The intervention did not significantly affect patient activation and QoL. However, post-hoc analysis suggested different effects across conditions. The program has a positive effect on the competence of adolescents in the transition phase. The study demonstrates that an intervention can be effective in preparing adolescents with chronic conditions for transitions. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

The interface between child/adolescent and adult mental health services: results from a European 28-country survey.

Science.gov (United States)

Signorini, Giulia; Singh, Swaran P; Marsanic, Vlatka Boricevic; Dieleman, Gwen; Dodig-Ćurković, Katarina; Franic, Tomislav; Gerritsen, Suzanne E; Griffin, James; Maras, Athanasios; McNicholas, Fiona; O'Hara, Lesley; Purper-Ouakil, Diane; Paul, Moli; Russet, Frederick; Santosh, Paramala; Schulze, Ulrike; Street, Cathy; Tremmery, Sabine; Tuomainen, Helena; Verhulst, Frank; Warwick, Jane; de Girolamo, Giovanni

2018-04-01

Transition-related discontinuity of care is a major socioeconomic and societal challenge for the EU. The current service configuration, with distinct Child and Adolescent Mental Health (CAMHS) and Adult Mental Health Services (AMHS), is considered a weak link where the care pathway needs to be most robust. Our aim was to delineate transitional policies and care across Europe and to highlight current gaps in care provision at the service interface. An online mapping survey was conducted across all 28 European Countries using a bespoke instrument: The Standardized Assessment Tool for Mental Health Transition (SATMEHT). The survey was directed at expert(s) in each of the 28 EU countries. The response rate was 100%. Country experts commonly (12/28) reported that between 25 and 49% of CAMHS service users will need transitioning to AMHS. Estimates of the percentage of AMHS users aged under 30 years who had has previous contact with CAMHS were most commonly in the region 20-30% (33% on average).Written policies for managing the interface were available in only four countries and half (14/28) indicated that no transition support services were available. This is the first survey of CAMHS transitional policies and care carried out at a European level. Policymaking on transitional care clearly needs special attention and further elaboration. The Milestone Study on transition should provide much needed data on transition processes and outcomes that could form the basis for improving policy and practice in transitional care.

The Transit/Admission Lounge study.

LENUS (Irish Health Repository)

Gilligan, P

2009-01-01

In response to persistent overcrowding of Emergency Departments in Ireland, the Department of Health and Health Service Executive provided funding for "Transit Lounge" areas to be built. These lounges were to provide a location for patients to wait in beds pending the availability of a ward bed. This research was performed to assess the impact of such a lounge on the overcrowding of the Emergency Department and on patient outcomes. The time period from the opening of the Transit Lounge was compared with the same period a year earlier. The Transit Lounge delivers a comfortable place for patients to wait. It does not reduce Emergency Department overcrowding and has been associated with an increased time waiting for a ward bed. The solution to overcrowding is the creation of real capacity in the system so that ward beds are available in acute hospitals for the "unscheduled unwell".

Recruiting for Prior Service Market

National Research Council Canada - National Science Library

Thomas, Brian A; Givens, Eric

2008-01-01

...) market based on data from: * DMDC (All services) * IRR (HRC-St. Louis) * AC/RC transition (HRC-Alexandria); 2) To recommend possible recruiting pools of applicants from the analyzed market data...

Failure Analysis for Composition of Web Services Represented as Labeled Transition Systems

Science.gov (United States)

Nadkarni, Dinanath; Basu, Samik; Honavar, Vasant; Lutz, Robyn

The Web service composition problem involves the creation of a choreographer that provides the interaction between a set of component services to realize a goal service. Several methods have been proposed and developed to address this problem. In this paper, we consider those scenarios where the composition process may fail due to incomplete specification of goal service requirements or due to the fact that the user is unaware of the functionality provided by the existing component services. In such cases, it is desirable to have a composition algorithm that can provide feedback to the user regarding the cause of failure in the composition process. Such feedback will help guide the user to re-formulate the goal service and iterate the composition process. We propose a failure analysis technique for composition algorithms that views Web service behavior as multiple sequences of input/output events. Our technique identifies the possible cause of composition failure and suggests possible recovery options to the user. We discuss our technique using a simple e-Library Web service in the context of the MoSCoE Web service composition framework.

Impacts of public transit improvements on ridership, and implications for physical activity, in a low-density Canadian city.

Science.gov (United States)

Collins, Patricia A; Agarwal, Ajay

2015-01-01

Public transit ridership offers valuable opportunities for modest amounts of daily physical activity (PA). Transit is a more feasible option for most Canadian commuters who live too far from work to walk or cycle, yet public transit usage in midsized Canadian cities has historically remained low due to inefficient transit service. The objectives of this longitudinal study were threefold: to assess whether the introduction of express transit service in the low-density city of Kingston, Ontario, has translated to greater transit use among a targeted employee group; to document the characteristics of those employees that have shifted to transit; and to examine the PA levels of employees using transit compared to other commute modes. An online survey was administered in October 2013 and October 2014 to all non-student employees at Queen's University. 1356 employees completed the survey in 2013, and 1123 in 2014; 656 of these employees completed the survey both years, constituting our longitudinal sample. Year-round transit ridership increased from 5.5% in 2013 to 8.5% in 2014 (p transit had fewer household-level opportunities to drive to work and more positive attitudes toward transit. Transit commuters accrued an average of 80 minutes/week of commute-related PA, and 50 minutes/week more total PA than those that commuted entirely passively. Kingston Transit's express service has stimulated an increase in transit ridership among one of their target employers, Queen's University. The findings from this study suggest that shifting to transit from entirely passive commuting can generate higher overall PA levels.

Transition-Focused Professional Development: An Annotated Bibliography of Essential Elements and Features of Professional Development

Science.gov (United States)

Holzberg, Debra G.; Clark, Kelly A.; Morningstar, Mary E.

2018-01-01

Transition professional development (PD) has been identified as a way to improve transition services; however, there is a dearth of literature on transition-focused PD. To learn more about the essential features of effective PD, 73 published articles were evaluated in the area of PD in both secondary transition and special education. Articles were…

Carbon outcomes of major land-cover transitions in SE Asia

DEFF Research Database (Denmark)

Ziegler, Alan D.; Phelps, Jacob; Yuen, Jia Qi

2012-01-01

Policy makers across the tropics propose that carbon finance could provide incentives for forest frontier communities to transition away from swidden agriculture (slash-and-burn or shifting cultivation) to other systems that potentially reduce emissions and/or increase carbon sequestration. However......-use regimes optimize or increase carbon sequestration. As some transitions may negatively impact other ecosystem services, food security, and local livelihoods, the entire carbon and noncarbon benefit stream should also be taken into account before prescribing transitions with ambiguous carbon benefits...

Thailand’s Work and Health Transition

Science.gov (United States)

Kelly, Matthew; Strazdins, Lyndall; Dellora, Tarie; Khamman, Suwanee; Seubsman, Sam-ang; Sleigh, Adrian C

2011-01-01

Thailand has experienced a rapid economic transition from agriculture to industry and services, and from informal to formal employment. It has much less state regulation and worker representation relative to developed nations, who underwent these transitions more slowly and sequentially, decades earlier. We examine the strengthening of Thai government policy and legislation affecting worker’s health, responding to international norms, a new democratic constitution, fear of foreign importer embargos and several fatal workplace disasters. We identify key challenges remaining for Thai policy makers, including legislation enforcement and the measurement of impacts on worker’s mental and physical health. PMID:22318916

Green synthesis and antimicrobial activity of silver nanoparticles using wild medicinal mushroom Ganoderma applanatum (Pers.) Pat. from Similipal Biosphere Reserve, Odisha, India.

Science.gov (United States)

Mohanta, Yugal Kishore; Singdevsachan, Sameer Kumar; Parida, Umesh Kumar; Panda, Sujogya Kumar; Mohanta, Tapan Kumar; Bae, Hanhong

2016-08-01

In the present study, green synthesis and cost effective approach of silver nanoparticles using wild medicinal mushroom Ganoderma applanatum (Pers.) Pat. from Similipal Biosphere Reserve, Odisha, India is reported. The biosynthesised AgNPs were characterised using UV-visible spectroscopy, particle analyser and scanning electron microscopy studies. It was found by dynamic light scattering analysis, that the average size and charges of the AgNPs were 133.0 ± 0.361 nm and -6.01 ± 5.30 mV, respectively. Moreover, the Fourier transform infrared study was also conducted to identify the biomolecules or functional groups responsible for the reduction of Ag and stabilisation of the AgNPs. The potential biomedical application with reference to antimicrobial activity of the synthesised AgNPs was investigated against some pathogenic microorganisms viz. Escherichia coli, Bacillus subtilis, Staphylococcus epidermidis, Vibrio cholerae, Staphylococcus aureus and Shigella flexneri.

Theory of Microcrediting in Transitional Economies

Directory of Open Access Journals (Sweden)

Nikola Kadoić

2009-06-01

Full Text Available In the early 1970s, Bangladeshi banker and economist Dr. Muhammad Yunus designed microcrediting – a socially sensitive and rightful system of fighting poverty and high unemployment rates. His Grameen Bank for the poorest of the poor in Bangladesh has so far lifted more than 3.2 million of individuals and their families out of poverty. After initial successes at home, microcredit was put into service for reducing unemployment and alleviating poverty in numerous countries throughout the world. This paper explores specific problems that a typical transitional country (like Croatia, is likely to face, with unemployment – the source of a vast number of related problems in a transitional society – as the focal point. The authors have attempted to incorporate particularities of a transitional economy into the original microcrediting principles. As a solution to problems afflicting the domestic economy, the authors define a global microcrediting system framework on the macroeconomic level, assuming at the same time that microcrediting of socially vulnerable groups can resolve many problems of modern transitional societies. Arising from the authors' primary intention – to consider in depth the functionality of microcrediting in general transition conditions – a transitional microcrediting system has been defined in general terms, and a corresponding financial and mathematical model developed.

‘Reaching Out’: international models for transitional care for teenage and young adult cancer patients

Directory of Open Access Journals (Sweden)

Charlotte Weston

2018-05-01

Full Text Available Background: This article will give an overview of ‘Reaching Out’, a project to identify international models of transitional care for adolescent and young adult (AYA cancer patients. Aims: •\tExplore provision of AYA cancer care in a different cultural context •\tIdentify new models of care for supporting transition between paediatric, AYA and adult care, and between acute and primary care •\tIdentify relevant resources and service designs that could be adapted for use in AYA services in the UK Methods: Three-week observational visit in a range of international healthcare settings. Findings: Similarities and differences between Australian and UK healthcare systems were observed. Models of care using a range of resources, including structured health and wellbeing programmes, were identified to support transitional care. Models of collaborative working across organisations were observed. The implementation of innovative programmes to improve efficiency of services and limit unnecessary impact on patient time and finances were identified, including the use of Skype for collaborative consultations between acute and community healthcare providers. Conclusions: Recommendations to benefit AYA patients with an improved range of supportive, holistic services and improved person-centred care include: •\tJoint AYA nursing posts between AYA centres to support transition •\tStructured AYA post-treatment health and wellbeing programme •\tProgramme of creative wellbeing projects to support transition at the end of treatment Scope use of Skype appointments within the AYA service Implications for practice: Observing service provision and healthcare practice in an international setting provides the opportunity to improve cross-cultural competence, which is essential to culturally competent care. Cross-cultural competence supports the improvement of patient care through experiential learning, sharing of ideas and connecting with others. The

Impacts of transit in a complete-streets context.

Science.gov (United States)

2012-04-01

The recent interest in smart growth, livable communities, and sustainability creates new opportunities for the adoption, expansion, and enhancement of transit services in communities across the U.S. Given that promoting livability and alternative mod...

Transit operations decision support systems (TODSS) : core functional requirements for identification of service disruptions and provision of service restoration options 1.0

Science.gov (United States)

2004-03-15

The Transit Operations Decision Support System (TODSS) Project was initiated to address concerns raised by transit agencies that have implemented and are using Automated Vehicle Location (AVL) and Computer Aided Dispatch Systems (CAD). This document ...

Assessing the health, functional characteristics, and health needs of youth attending a noncategorical transition support program.

Science.gov (United States)

Woodward, Jason F; Swigonski, Nancy L; Ciccarelli, Mary R

2012-09-01

To assess the health, functional characteristics, and health care service needs of youth and young adults with special health care needs attending a comprehensive, noncategorical transition program. A self-administered survey was developed from national health surveys and clinical experience to assess concepts identified as important for successful transition to adulthood. Surveys were mailed to 198 parents of youth and young adults with special health care needs attending the transition clinic. Parents were asked about the youth's health, functional status, and health care services needed. The clinical database provided demographic and patient health characteristics. Results were compared against the 2005-2006 National Survey of Children with Special Health Care Needs. Forty-four percent of surveys were returned. Average age of youth was 17.5 (11-22) years old and diagnoses included cerebral palsy (36%), spina bifida (10%), developmental delay or Down syndrome (17%), and autism (6%). Most youth needed assistance with personal care (69%) and routine needs (91%) and used assistive devices (59%). Compared with the 2005-2006 National Survey of Children with Special Health Care Needs, parents reported higher needs for all services except mental health care and tobacco or substance use counseling. Forty three percent reported at least one unmet health need. Few parents reported the need for counseling on substance use (1%), sexual health screening (16%), nutrition (34%), and exercise (41%). Youth attending our transition program had more functional limitations, poorer reported health status, different diagnosis distribution, and higher levels of needed health services. Few parents identified needs for other recommended adolescent preventive services. Transition programs should assess patient health characteristics and service needs to design effective patient-centered services. Copyright © 2012 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All

Inherent characteristics of sawtooth cycles can explain different glacial periodicities

NARCIS (Netherlands)

Omta, Anne Willem; Kooi, Bob W.; Voorn, van G.A.K.; Rickaby, Rosalind E.M.; Follows, Michael J.

2016-01-01

<p>At the Mid-Pleistocene Transition about 1 Ma, the dominant periodicity of the glacial-interglacial cycles shifted from ~40 to ~100 kyr. Here, we use a previously developed mathematical model to investigate the possible dynamical origin of these different periodicities. The model has two

Refocusing and Evolving Subseasonal-to-Seasonal Services in NOAA's National Weather Service

Science.gov (United States)

Timofeyeva-Livezey, M. M.; Horsfall, F. M. C.; Silva, V.; Mangan, M. R.; Meyers, J. C.; Zdrojewski, J.

2017-12-01

NOAA's National Weather Service (NWS) recently completed a reorganization to better support its goal to build a Weather-Ready Nation. As part of the reorganization, NWS streamlined its 11 national service programs, including climate services, to provide a more structured approach to supporting service delivery needs. As the American public increasingly requests information at sub-seasonal and seasonal time scales for decision making, the NWS Climate Services Program is striving to meet those needs by accelerating transition of research to operations, improving delivery of products and services, and enhancing partnerships to facilitate provision of seamless weather, water, and climate products and services at regional and local scales. Additionally, NWS forecasters are requesting more tools to be able to put severe weather and water events into a climate context to provide more effective impact-based decision support services (IDSS). This paper will describe the activities to more effectively integrate climate services into the NWS suite of environmental information, the roles of the NWS offices supporting or delivering sub-seasonal and seasonal information to the US public, and engaging NWS core and deep-core partners in provision of information on climatological risks and preparedness as a part of IDSS. We will discuss the process by which we collect user requests and/or needs and the NWS process that allows us to move these requests and needs through a formal requirements validation process and thus place the requirement on a path to identify a potential solution for implementation. The validation of a NWS climate-related requirement is also key to identify research, development, and transition mission delivery needs that are supported through the Office of Oceanic and Atmospheric Research (OAR) Climate Program Office (CPO). In addition, we will present the outcomes of key actions of the first ever NWS National Climate Services Meeting (NCSM) that was held in May

Caracterización petrográfica, geoquímica y geocronológica en rocas ígneas intrusivas de la cuenca Cauca-Patía (CCP), Departamento del Cauca, Colombia

OpenAIRE

Jerez Heredia, Edith Katherine

2012-01-01

Al sur de la Cuenca Cauca-Patía, en el departamento del Cauca, Colombia, afloran once cuerpos intrusivos neógenos cuya composición varía de diorita, granodiorita a granito. La composición química de los granitoides muestreados presenta afinidad calcoalcalina, calcoalcalina alta en potasio y toleítica, dentro del rango de los granitoides cordilleranos tipo I. Según el análisis de datos geocronológicos se infieren tres eventos plutónicos que afectaron el área durante el Oligoceno-Mioceno inferi...

Ação de herbicidas sobre mecanismos de defesa das plantas aos patógenos

Directory of Open Access Journals (Sweden)

Rizzardi Mauro Antônio

2003-01-01

Full Text Available As plantas necessitam defender-se continuamente do ataque de agentes biológicos e de estresses do ambiente. A imobilidade e a falta de sistema imunológico, como ocorre em animais, fizeram com que as plantas desenvolvessem mecanismos de defesa, em que cada célula possui tanto capacidade de defesa induzida quanto pré-formada. No entanto, esses mecanismos podem ser influenciados pelo uso de herbicidas. A presente revisão objetivou apresentar os efeitos de herbicidas em mecanismos de defesa das plantas contra patógenos, bem como analisar as possíveis conseqüências desse conhecimento no manejo de plantas daninhas e de culturas. Alguns herbicidas influenciam a severidade de doenças, induzindo ou inibindo a síntese de fitoalexinas. Herbicidas do grupo químico difeniléteres geram espécies reativas de oxigênio, as quais mediam a ativação de genes de defesa responsáveis pela síntese de fitoalexinas e também por reação de hipersensibilidade. O uso de subdoses de glyphosate ocasiona efeito contrário, diminuindo a produção de fitoalexinas e aumentando a severidade de doenças. A constatação desses efeitos requer a adoção de estratégias de manejo que minimizem seus impactos negativos ou que se beneficiem desses efeitos, como pode ocorrer quando do uso de bioherbicidas.

Collaborative Care Transitions Symposium: Insights from Participants.

Science.gov (United States)

Jeffs, Lianne; Saragosa, Marianne; Zahradnik, Michelle; Maione, Maria; Hindle, Aimee; Santiago, Cecilia; Krock, Murray; Stergiopoulos, Vicky; Bulmer, Beverly; Mitchell, Kaleil; McNamee, Colleen; Ramji, Noor

2017-01-01

There are promising signs that interprofessional collaborative practice is associated with quality care transitions and improved access to patient-centred healthcare. A one-day symposium was held to increase awareness and capacity to deliver quality collaborative care transitions to interprofessional health disciplines and service users. A mixed methods study was used that included a pre-post survey design and interviews to examine the impact of the symposium on knowledge, attitudes and practice change towards care transitions and collaborative practice with symposium participants. Our survey results revealed a statistically significant increase in only a few of the scores towards care transitions and collaborative practice among post-survey respondents. Three key themes emerged from the qualitative analysis, including: (1) engaging the patient at the heart of interprofessional collaboration and co-design of care transitions; (2) having time to reach out, share and learn from each other; and (3) reflecting, reinforcing and revising practice. Further efforts that engage inter-organizational learning by exchanging knowledge and evaluating these forums are warranted. Copyright © 2017 Longwoods Publishing.

78 FR 16837 - Privacy Act of 1974; System of Records

Science.gov (United States)

2013-03-19

... uses this information to obtain customer feedback concerning their service experience and the level of... listed under ``COMMERCE/ PAT-TM-20 Customer Call Center, Assistance and Satisfaction Survey Records... through the agency's telephone support system or customer service centers. The Privacy Act notice is being...

The Dilemma for USSOCOM: Transitioning SOF-Peculiar to Service-Common

Science.gov (United States)

2012-02-15

Operations-peculiar (SO-peculiar or SOF-peculiar) to Service-common, while the third implication suggests a lack of “ advertising ”, i.e. the need for a...Portfolio Management ( CPM ) system which seeks to optimize capability investments across the defense enterprise.59 Though CPMs are charged to identify...capabilities as Service-common. Collectively though they do offer several avenues in which SOCOM can “ advertise ” them, and whereby through mutual

Transit Traffic Analysis Zone Delineating Method Based on Thiessen Polygon

Directory of Open Access Journals (Sweden)

Shuwei Wang

2014-04-01

Full Text Available A green transportation system composed of transit, busses and bicycles could be a significant in alleviating traffic congestion. However, the inaccuracy of current transit ridership forecasting methods is imposing a negative impact on the development of urban transit systems. Traffic Analysis Zone (TAZ delineating is a fundamental and essential step in ridership forecasting, existing delineating method in four-step models have some problems in reflecting the travel characteristics of urban transit. This paper aims to come up with a Transit Traffic Analysis Zone delineation method as supplement of traditional TAZs in transit service analysis. The deficiencies of current TAZ delineating methods were analyzed, and the requirements of Transit Traffic Analysis Zone (TTAZ were summarized. Considering these requirements, Thiessen Polygon was introduced into TTAZ delineating. In order to validate its feasibility, Beijing was then taken as an example to delineate TTAZs, followed by a spatial analysis of office buildings within a TTAZ and transit station departure passengers. Analysis result shows that the TTAZs based on Thiessen polygon could reflect the transit travel characteristic and is of in-depth research value.

Pediatric Provider's Perspectives on the Transition to Adult Health Care for Youth with Autism Spectrum Disorder: Current Strategies and Promising New Directions

Science.gov (United States)

Kuhlthau, Karen A.; Warfield, Marji E.; Hurson, Jill; Delahaye, Jennifer; Crossman, Morgan K.

2015-01-01

Few youth with autism spectrum disorder (ASD) nationally report receiving services to help them transition from the pediatric health care system to the adult health care system. For example, only one-fifth (21.1%) of youth with ASD receive any transition planning services. To better understand why the transition from pediatric to adult health care…

To Evaluate Zero Emission Propulsion and Support Technology for Transit Buses

Energy Technology Data Exchange (ETDEWEB)

Kevin Chandler; Leslie Eudy

2006-11-01

This report provides evaluation results for prototype fuel cell transit buses operating at Santa Clara Valley Transportation Authority (VTA) in San Jose, California, in partnership with the San Mateo County Transit District in San Carlos, California. VTA has been operating three fuel cell transit buses in extra revenue service since February 28, 2005. This report provides descriptions of the equipment used, early experiences, and evaluation results from the operation of the buses and the supporting hydrogen infrastructure from March 2005 through July 2006.

ASMATRA: Rankin g ASs Providing Transit Service to Malware Hosters

OpenAIRE

Wagner , Cynthia; François , Jérôme; State , Radu; Dulaunoy , Alexandre; Engel , Thomas; Massen , Gilles

2013-01-01

International audience; The Internet has grown into an enormous network offering a variety of services, which are spread over a multitude of domains. BGP-routing and Autonomous Systems (AS) are the key components for maintaining high connectivity in the Internet. Unfortunately, Internet Service Providers (ISPs) operating ASs do not only host normal users and content, but also malicious content used by attackers for spreading malware, hosting phishing web-sites or performing any kind of fraudu...

Transition radiation and transition scattering

International Nuclear Information System (INIS)

Ginzburg, V.L.

1982-01-01

Transition radiation is a process of a rather general character. It occurs when some source, which does not have a proper frequency (for example, a charge) moves at a constant velocity in an inhomogeneous and (or) nonstationary medium or near such a medium. The simplest type of transition radiation takes place when a charge crosses a boundary between two media (the role of one of the media may be played by vacuum). In the case of periodic variation of the medium, transition radiation possesses some specific features (resonance transition radiation or transition scattering). Transition scattering occurs, in particular, when a permittivity wave falls onto an nonmoving (fixed) charge. Transition scattering is closely connected with transition bremsstrahlung radiation. All these transition processes are essential for plasma physics. Transition radiation and transition scattering have analogues outside the framework of electrodynamics (like in the case of Vavilov-Cherenkov radiation). In the present report the corresponding range of phenomena is elucidated, as far as possible, in a generally physical aspect. (Auth.)

An Analysis of Public Transit Connectivity Index in Tehran. The Case Study: Tehran Multi-Modal Transit Network

Directory of Open Access Journals (Sweden)

Amir Reza Mamdoohi

2016-10-01

Full Text Available Public transit is a major priority in modern management of large cities and metropolitan areas in particular. Public transit systems in such cities consist of a large number of nodes and lines which are represented by a complex network. A station for public transit is a bridge between the people and public transit network, based on which, the concept of input and output power for each station can be defined. The objective of this study is the application of the transit connectivity indices to the multimodal transit network in the city of Tehran. The public transit network data employed in this study is taken from Tehran Traffic Control Company, and Tehran Urban and Suburban Railway Operation Company. The methodology for measuring transit connectivity consists of three measures: Node connectivity, Line connectivity and Regional connectivity, where activity density is applied to these measures. The results of node connectivity analysis shows that most of the node connectivity in concentrated in the city center with many nodes in the center along routes going north and south. The line connectivity analysis shows that there is a concentration of highly connected lines that are near Tehran municipality region 12 and 16. Finally, we find that areas with more metro and bus facilities with respect to the other areas, have a better regional connectivity. One of these areas includes Sadeghiyeh Metro Station which is the junction of Tehran Metro Line 2 and Tehran Metro Line 5 which have a high connectivity power. Results of this study can be used to suggest some ideas on how future investments in rail and bus should be prioritized. Particularly in Transit Oriented Development (TOD and sustainble development projects, urban planners can design transit stations with high performance to access the crucial services in poor areas.

Metaphors as Two-Way Mirrors: Illuminating Preservice to In-Service Teacher Identity Development

Science.gov (United States)

Buchanan, John

2015-01-01

The transition from pre-service to in-service can be difficult for teachers. One means of looking into the minds and hearts of such teachers is to elicit the metaphors they adopt for themselves. Previous studies have indicated that during this transition much of the confidence, idealism and optimism of teacher metaphors is displaced by bleak and…

9 CFR 3.140 - Care in transit.

Science.gov (United States)

2010-01-01

... Warmblooded Animals Other Than Dogs, Cats, Rabbits, Hamsters, Guinea Pigs, Nonhuman Primates, and Marine... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Care in transit. 3.140 Section 3.140 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL...

9 CFR 3.116 - Care in transit.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Care in transit. 3.116 Section 3.116 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Marine...

9 CFR 3.39 - Care in transit.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Care in transit. 3.39 Section 3.39 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Guinea...

9 CFR 3.17 - Care in transit.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Care in transit. 3.17 Section 3.17 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Dogs and...

9 CFR 3.64 - Care in transit.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Care in transit. 3.64 Section 3.64 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment and Transportation of Rabbits...

9 CFR 3.90 - Care in transit.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Care in transit. 3.90 Section 3.90 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Nonhuman...

Improving TOGAF ADM 9.1 Migration Planning Phase by ITIL V3 Service Transition

Science.gov (United States)

Hanum Harani, Nisa; Akhmad Arman, Arry; Maulana Awangga, Rolly

2018-04-01

Modification planning of business transformation involving technological utilization required a system of transition and migration planning process. Planning of system migration activity is the most important. The migration process is including complex elements such as business re-engineering, transition scheme mapping, data transformation, application development, individual involvement by computer and trial interaction. TOGAF ADM is the framework and method of enterprise architecture implementation. TOGAF ADM provides a manual refer to the architecture and migration planning. The planning includes an implementation solution, in this case, IT solution, but when the solution becomes an IT operational planning, TOGAF could not handle it. This paper presents a new model framework detail transitions process of integration between TOGAF and ITIL. We evaluated our models in field study inside a private university.

Avaliação da estabilidade e da qualidade do patê de presunto, adicionado de globina bovina e de caseinato de sódio, como agente emulsionante

OpenAIRE

Silva Janaína Guernica; Morais Harriman Aley; Junqueira Roberto Gonçalves; Oliveira Afonso de Liguori; Silvestre Marialice Pinto Coelho

2003-01-01

Este trabalho foi conduzido para avaliar o efeito da incorporação das globinas bovina extraída pelo método da acetona acidificada (GT) e pelo da carboximetilcelulose (GCMC) e do caseinato de sódio (CA) sobre a composição química e as qualidades microbiológica e sensorial do patê de presunto. Foi, ainda, avaliada a estabilidade do produto durante os 45 dias de estocagem sob refrigeração, por meio das determinações de pH e do grau de oxidação lipídica. De acordo com os resultados obtidos, pôde-...

Quality by design (QbD), Process Analytical Technology (PAT), and design of experiment applied to the development of multifunctional sunscreens.

Science.gov (United States)

Peres, Daniela D'Almeida; Ariede, Maira Bueno; Candido, Thalita Marcilio; de Almeida, Tania Santos; Lourenço, Felipe Rebello; Consiglieri, Vladi Olga; Kaneko, Telma Mary; Velasco, Maria Valéria Robles; Baby, André Rolim

2017-02-01

Multifunctional formulations are of great importance to ensure better skin protection from harm caused by ultraviolet radiation (UV). Despite the advantages of Quality by Design and Process Analytical Technology approaches to the development and optimization of new products, we found in the literature only a few studies concerning their applications in cosmetic product industry. Thus, in this research work, we applied the QbD and PAT approaches to the development of multifunctional sunscreens containing bemotrizinol, ethylhexyl triazone, and ferulic acid. In addition, UV transmittance method was applied to assess qualitative and quantitative critical quality attributes of sunscreens using chemometrics analyses. Linear discriminant analysis allowed classifying unknown formulations, which is useful for investigation of counterfeit and adulteration. Simultaneous quantification of ethylhexyl triazone, bemotrizinol, and ferulic acid presented at the formulations was performed using PLS regression. This design allowed us to verify the compounds in isolation and in combination and to prove that the antioxidant action of ferulic acid as well as the sunscreen actions, since the presence of this component increased 90% of antioxidant activity in vitro.

Exploring the Transition From Batch to Online

DEFF Research Database (Denmark)

Jørgensen, Anker Helms

2010-01-01

of the truly interactive use of computers known today. The transition invoked changes in a number of areas: technological, such as hybrid forms between batch and online; organisational such as decentralization; and personal as users and developers alike had to adopt new technology, shape new organizational...... structures, and acquire new skills. This work-in-progress paper extends an earlier study of the transition from batch to online, based on oral history interviews with (ex)-employees in two large Danish Service Bureaus. The paper takes the next step by ana-lyzing a particular genre: the commercial computer...

Price Elasticity of Demand and Capacity-Restraint Transit Fare Strategy: A Case Study of Bangkok Mass Transit System

Directory of Open Access Journals (Sweden)

Ackchai Sirikijpanichkul

2015-01-01

Full Text Available Traffic congestion is a chronic problem of Bangkok. Similar to other metropolises, the city perpetually seeks for alternatives to road travel. Mass rapid transit seems to be the only way out that is expected to mitigate traffic congestion in the city. However, without common fare system, travelers need to pay an initial entrance fee every time they enter each transit system. This excess cost tapers the demand and affects the efficient use of the system. This research investigates the influence of fare price on transit use which is measured by price elasticity of demand and proposes the optimum fare price if the common fare is used. The analysis is based on the findings from the stated preference survey techniques. Finally, the conclusion on fare level that encourage more patronage, maintain service quality and operator revenue is addressed.

Study of Bi-2212 phase doped Sn(Pb) by means of pat

International Nuclear Information System (INIS)

Ma Qingzhu; Huang Xiaoqian; Xiong Xiaotao

1997-01-01

Investigation on the effect of Sn/Pb-doped Bi-2212 superconductors has been carried out by the simultaneous measurements of the spectra of positron annihilation lifetime and positron Doppler broadening, together with X-ray diffraction. The results of samples with different doping level show the occupation of Sn atoms on Bi sites. At weak doping level, Sn doping results in a enhancement of cooperation between layers and increment of superconducting transition temperature. At the strong doping level, Sn atoms occupy the sites of Cu-O layers, and at the same time, the other nonsuperconducting phases appear, which results in a decline of the superconducting transition temperature

Telecommunications: Additional Federal Efforts Could Help Advance Digital Television Transition

Science.gov (United States)

2002-11-01

The transition to broadcast digital television(DTV) will provide new television services and the improved picture quality of 'high definition television'. It will also allow some portions of the radiofrequency spectrum used for broadcasting to be returned for public safety and commercial uses. The Congress set December 2006 as the target date for completing the DTV transition and turning the analog broadcast signals. However, this date can be extended if fewer than 85 percent of households in a market are able to receive the digital signals. GAO (General Accounting Office) was asked to assess issues related to the DTV transition.

Primera incursión en la obtención de curieles libre de patógenos específicos en Cuba

Directory of Open Access Journals (Sweden)

Bárbara O González Navarro

2014-01-01

Full Text Available Título corto: Primera incursión en la obtención de curieles SPF en Cuba Título en ingles: First foray into the production of specific pathogen-free guinea pigs in Cuba Resumen: Resultados confiables y económicos solo son obtenidos cuando los animales de experimentación son aislados de factores ambientales y biológicos, implantándose en el biomodelo una microbiota normal, lejos de la presencia de microorganismos patógenos. El objetivo de la investigación fue obtener curieles libre de patógenos específicos por cesárea aséptica, mantenidos en aisladores y alimentados con dietas estériles. Se realizaron 26 histerectomías. Los animales fueron alimentados con una fórmula modificada (L-477 en forma de papilla hasta los 21 días y permanentemente después la C-484 sólida y granulada, esterilizadas a 121oC/20 minutos o a 1,5Mrad. Además fueron suplementados con vitamina C y B1. El forraje o heno fue consumido a partir de la primera generación. La microbiota gastrointestinal se administró por vía oral en 0,5 ml de una dilución de 10-6/g de contenido de la porción final del íleon, ciego y principio del colon de curieles, a las 24 y 48 horas del nacimiento. Se utilizó para el monitoreo microbiológico caldo Tioglicolato, caldo Triptona Soya y caldo Saboraud incubados aeróbicamente a temperatura de 55, 37y 25oC respectivamente. Se obtuvieron 51 neonatos. La mortalidad más alta se registró entre los primeros 10 días de edad (58,8%. Se lograron 12 animales (3 machos y 9 hembras, 6 de las hembras se reprodujeron aproximadamente a los 9 meses de edad, lográndose 11 crías por parto normal. La metodología aplicada permitió obtener curieles libres de Salmonella sp, Pasteurella sp, Streptococcus del tipo A y C, Bordetella bronchiseptica, Toxoplasma gondii, Virus Sendai y parásitos internos y externos. Palabras clave: curieles, libre de patógenos específicos, aisladores, histerectomía y dietas estériles. Abstract

Patèr kaì poietés : numenio y la interpretación de Timeo 28 c 3

Directory of Open Access Journals (Sweden)

Gabriela F. Müeller

2009-09-01

Full Text Available En el célebre pasaje Timeo 28 c 3-5 leemos: “Descubrir al hacedor y padre de este universo es difícil, pero, una vez descubierto, comunicárselo a todos es imposible.” En el presente trabajo me propongo indagar la peculiar interpretación que realiza Numenio de estas líneas y el papel que dicha exégesis cumple en la conformación de su sistema metafísico. En este sentido, intentaré establecer los motivos que llevan a Numenio a invertir los términos del Timeo y a distinguir un primer dios (patér de un segundo dios (poietés, identificando a este último con el demiurgo. Para esto analizaré algunos fragmentos conservados de su obra Perì tagathoû en los que caracteriza al primer y al segundo dios, procurando poner de manifiesto en qué otros textos platónicos podría basarse esta doctrina y en qué medida ella representa una innovación en la historia de la interpretación de la filosofía de Platón realizada por los platónicos.

Using Mobile Phone Technology to Support Young Liver Transplant Recipients Moving to Adult Services.

Science.gov (United States)

Coad, Jane; Toft, Alex; Claridge, Lee; Ferguson, James; Hind, Jonathon; Jones, Rebecca; McClean, Patricia; McKiernan, Patrick; Samyn, Marianne; Taylor, Rachel

2017-06-01

The process and preparation of moving from child to adult services (transition) is a challenging period of time for young people and represents significant changes in care and support systems. The proliferation of mobile phone applications for health purposes suggests that it is an area for further investigation. The review explores the potential to use mobile phone technology to help support young liver transplant recipients moving to adult services. It represents the first review conducted in this specialism and considers a new model of support for young liver patients. A systematic rapid review of the published peer-reviewed literature. Two searches were conducted: Search 1: the use of technology to support transition to adult services (6 studies) and Search 2: how best to support liver transplant recipients during transition (6 studies). Research shows that to achieve positive transition young people need information about their condition and transition. The process needs to be guided by transition readiness, rather than the young persons' age. Although parents and support networks should be in place and are valued, transition should build upon self-management and independence. Results suggest that there appears to be scope to use mobile phone technology to support transition. This is the first time a review has explored the types of issues or concerns facing liver transplant patients and how these can be addressed through mobile phone technology.

A verification strategy for web services composition using enhanced stacked automata model.

Science.gov (United States)

Nagamouttou, Danapaquiame; Egambaram, Ilavarasan; Krishnan, Muthumanickam; Narasingam, Poonkuzhali

2015-01-01

Currently, Service-Oriented Architecture (SOA) is becoming the most popular software architecture of contemporary enterprise applications, and one crucial technique of its implementation is web services. Individual service offered by some service providers may symbolize limited business functionality; however, by composing individual services from different service providers, a composite service describing the intact business process of an enterprise can be made. Many new standards have been defined to decipher web service composition problem namely Business Process Execution Language (BPEL). BPEL provides an initial work for forming an Extended Markup Language (XML) specification language for defining and implementing business practice workflows for web services. The problems with most realistic approaches to service composition are the verification of composed web services. It has to depend on formal verification method to ensure the correctness of composed services. A few research works has been carried out in the literature survey for verification of web services for deterministic system. Moreover the existing models did not address the verification properties like dead transition, deadlock, reachability and safetyness. In this paper, a new model to verify the composed web services using Enhanced Stacked Automata Model (ESAM) has been proposed. The correctness properties of the non-deterministic system have been evaluated based on the properties like dead transition, deadlock, safetyness, liveness and reachability. Initially web services are composed using Business Process Execution Language for Web Service (BPEL4WS) and it is converted into ESAM (combination of Muller Automata (MA) and Push Down Automata (PDA)) and it is transformed into Promela language, an input language for Simple ProMeLa Interpreter (SPIN) tool. The model is verified using SPIN tool and the results revealed better recital in terms of finding dead transition and deadlock in contrast to the

Social Cognitive Career Theory as Applied to the School-to-Work Transition

Science.gov (United States)

Kelly, Mary E.

2009-01-01

The school-to-work (STW) transition occurs when young adults leave education and enter the full-time workforce. Most high school students in the United States will not graduate from a 4-year college and instead transition into the world of work, many filling positions in sales and service. Supporters of the STW movement advocate for educational…

Operational Assessment of Paralympics Transit Systems : Low-Floor Buses, Lift-Equipped Buses, and Signage

Science.gov (United States)

1997-02-01

From August 15-25, Atlanta hosted the paralympics, a world-class athletic competition for athletes with disabilities. To support the Paralympics, a specialized transit service was planned and deployed to service the travel needs of athletes, trainers...

75 FR 23254 - Office of Special Education and Rehabilitative Services; Overview Information; Training and...

Science.gov (United States)

2010-05-03

... DEPARTMENT OF EDUCATION Office of Special Education and Rehabilitative Services; Overview... special education, early intervention services, transition services, and related services; (iii... Special Education Programs' (OSEP) technical assistance and dissemination centers ( http://www.ed.gov...

Transition care for children with special health care needs.

Science.gov (United States)

Davis, Alaina M; Brown, Rebekah F; Taylor, Julie Lounds; Epstein, Richard A; McPheeters, Melissa L

2014-11-01

Approximately 750,000 children in the United States with special health care needs will transition from pediatric to adult care annually. Fewer than half receive adequate transition care. We had conversations with key informants representing clinicians who provide transition care, pediatric and adult providers of services for individuals with special health care needs, policy experts, and researchers; searched online sources for information about currently available programs and resources; and conducted a literature search to identify research on the effectiveness of transition programs. We identified 25 studies evaluating transition care programs. Most (n = 8) were conducted in populations with diabetes, with a smaller literature (n = 5) on transplant patients. We identified an additional 12 studies on a range of conditions, with no more than 2 studies on the same condition. Common components of care included use of a transition coordinator, a special clinic for young adults in transition, and provision of educational materials. The issue of how to provide transition care for children with special health care needs warrants further attention. Research needs are wide ranging, including both substantive and methodologic concerns. Although there is widespread agreement on the need for adequate transition programs, there is no accepted way to measure transition success. It will be essential to establish consistent goals to build an adequate body of literature to affect practice. Copyright © 2014 by the American Academy of Pediatrics.

System and prospects of China's intercity rail transit technology

Science.gov (United States)

Gong, Ming

2018-06-01

City clusters and metropolitan areas in China are flourishing in the midst of the deepening urbanization in the country, thereby resulting in the emergence of intercity rail transit. Intercity railways connect mainline and urban railways for an integrated regional transportation system that underpins and leads the development of city clusters and metropolitan areas. This study explores the development mode and service characteristics of intercity rail transit, as well as proposes overviews on this system and prospects of its future technology in China.

“Church trailblazer Rev Pat Storey on Weight Watchers, caffeine and how she named her dog after former New York Mayor”: News representations of the first female Anglican Bishop in the UK and Ireland

OpenAIRE

Power, Kate

2017-01-01

The first female bishop in the Anglican Church of the UK and Ireland was consecrated on November 30, 2013. For many within the Anglican Communion, the appointment of Reverend Pat Storey as Bishop of Meath and Kildare represented the opening of a longawaited new chapter in the history of Anglicanism. It is also potentially an occasion of considerable interest for both Irish historians and discourse analysts. For, although questions of gender and language have been widely considered in recent y...

Two Interlocked Triads in Pat Kinevane’s Recent Plays: Self-Soul-Conscousness and Birth-Death-Rebirth

Directory of Open Access Journals (Sweden)

Nicoleta Stanca

2017-05-01

Full Text Available Everyting conceivable, all that has ever been imagined, can be included in our minds and souls. As psyche means “breath”, “soul” and “mind”, it points to the relevance of psychology as a study of mental, emotional and spiritual processes involved in our identity make-up. One of the main organizers of our self and psychological experiences is our relationhip with death: our fear of abandonement and of being alone when conceiving our own death, the fear of the loss of the others, leading to the fear of attachment and emotional death. Pat Kinevane, a contemporary Irish playright, deals, in his 2005 play, Forgotten, with the idea of family and social abandonment of old people in nursing homes. The interconnected stories of Dora, Eucharia, Flor and Gustus, the characters in the play, aged 80-100 years old, living in separate retirement and care facilities around Ireland, reveal these fears. Mental illness in the current explosion of anxiety is also crucial to our identity. Another play by Kinevane, Silent (2010, ends with the word silent, which indicates the insanity, invisibility and ultimately the death of the protagonist, Tino McGoldring, a homeless man tormented by the suicide of his brother. His self after the loss of his brother, wife, family, job, mind is constructed in relation to the past and the imaginary world of the Italian-American icon of the film industry of the 1920s, Rudolph Valentino.

Status of Credentialing Structures Related to Secondary Transition: A State-Level Policy Analysis

Science.gov (United States)

Simonsen, Monica L.; Novak, Jeanne A.; Mazzotti, Valerie L.

2018-01-01

To understand the current status of transition-related credentialing systems in driving personnel preparation, it is necessary to identify which state education and rehabilitation services agencies are currently providing certification and licensure in the area of secondary transition. The purpose of this study was to examine the current state of…

Transition through Teamwork: Professionals Address Student Access

Science.gov (United States)

Bube, Sue Ann; Carrothers, Carol; Johnson, Cinda

2016-01-01

Prior to 2013, there was no collaboration around the transition services for deaf and hard of hearing students in Washington State. Washington had numerous agencies providing excellent support, but those agencies were not working together. It was not until January 29, 2013, when pepnet 2 hosted the Building State Capacity to Address Critical…

Older peoples experiences involving the decision to transition to an aged care home

Directory of Open Access Journals (Sweden)

Zamanzadeh Vahid

2016-08-01

Full Text Available The decision to relocate to an aged care home can is important change in older adults live but little attention has been paid to their experiences of this decision. The study explored older people’s experiences involving the decision to transition to an aged care home. Data were obtained via semi-structured interviews with 17 participants, which were content analyzed. Results: Transition motives, ambiguity, participation in decision making and decision making meaning were four themes extracted through data analysis. Conclusions: In the main, the decision to transition to an aged care home had been made without the older person’s participation. In addition, due to inadequate information about aged care home services, participants experienced a great deal of ambiguity in the decision-making process. Moreover, transition into aged care homes had different meaning for the participants. The findings suggest that far greater emphasis must be placed on having older people involved in the decision to move into residential aged care, providing them with more information about service offerings and making psychological support accessible to them prior to and following transition to the home

Transition from paediatric to adult healthcare for young people with cystic fibrosis: Parents' information needs.

Science.gov (United States)

Coyne, Imelda; Malone, Helen; Chubb, Emma; While, Alison E

2018-01-01

Parents of young people with cystic fibrosis (YPWCF) play an important role during the transition from paediatric to adult health services. There is limited evidence on parental information needs and the extent to which they are met. An online survey was conducted targeting a finite population of 190 parents of YPWCF in Ireland. Fifty-nine parents responded (31% response rate). Parents reported the need for more general preparation and timing of the transfer, more information regarding the differences between adult and child health services and how their child will self-manage his/her illness in the future. Most parents received information on the timing of transfer and new healthcare providers but reported being insufficiently informed about their legal status relating to medical confidentiality for their adult child and community resources available for their child after transition to adult health services. The findings highlight the importance of information and preparation for caregivers as well as young people to promote successful transition to adult healthcare. Providing parents with clear information and anticipatory guidance are simple changes in practice that may lead to improvements in transition experiences.

Disparities in Life Course Outcomes for Transition-Aged Youth with Disabilities.

Science.gov (United States)

Acharya, Kruti; Meza, Regina; Msall, Michael E

2017-10-01

Close to 750,000 youth with special health care needs transition to adult health care in the United States every year; however, less than one-half receive transition-planning services. Using the "F-words" organizing framework, this article explores life course outcomes and disparities in transition-aged youth with disabilities, with a special focus on youth with autism, Down syndrome, and cerebral palsy. Despite the importance of transition, a review of the available literature revealed that (1) youth with disabilities continue to have poor outcomes in all six "F-words" domains (ie, function, family, fitness, fun, friends, and future) and (2) transition outcomes vary by race/ethnicity and disability. Professionals need to adopt a holistic framework to examine transition outcomes within a broader social-ecological context, as well as implement evidence-based transition practices to help improve postsecondary outcomes of youth with disabilities. [Pediatr Ann. 2017;46(10):e371-e376.]. Copyright 2017, SLACK Incorporated.

The academic transitional experiences of masters’ students at the University of the Western Cape

Directory of Open Access Journals (Sweden)

Jeffrey C. Hoffman

2012-08-01

Full Text Available Transition has been a major focus of educational institutions. However, most of the research into student transition focuses on the challenges related the transition from high school to university. Not much emphasis has been placed on the transition from undergraduate topostgraduate studies, despite the steadily increasing postgraduate enrolment rates in higher education institutions. The discrepancy between the enrolment and completion rates is an indication that postgraduate students are facing transitional challenges when engaging with postgraduate studies. The aim of this research study was to describe the academic transitional experiences of masters’ students in the Faculty of Community Health Sciences at the University of the Western Cape. The objectives were to determine the academic preparedness of postgraduate students, to explore their primary motivations for pursuing postgraduate studies, and to assess their utilisation of the available support services at UWC.A quantitative, exploratory, descriptive research design was employed. A cross-sectional survey was conducted with masters’ students during 2009, using convenience sampling. Data was statistically analysed using the SPSS to provide descriptive statistics. The majority of the sample indicated a lack of academic preparedness, even though most of them had a bachelor’s degree. The primary reasons listed as motivation for master’s study were to improve knowledge and reaching self-actualisation. The majority is still eager to complete their studies. Most support systems were utilised and students rated these services as a positive experience that facilitates smooth academic transition. However, concerns are that not many students utilised the academic writing centre and those who did, rated the overall service as average. One of the main recommendations was that a research culture needs to be established at undergraduate level, as this would give students greater exposure to

Transition Scenarios for Young People with Learning Disabilities in Spain. Relationships and Discrepancies

Science.gov (United States)

Pallisera, Maria

2011-01-01

This paper examines transition scenarios to adult and active life in Spain from an inclusive viewpoint. For people with learning disabilities, the transition to adult life is a particularly complex process worldwide, and this is especially true in Spain. The multitude of services and professionals involved, the diversity of views regarding what…

Nursing perception of patient transitions from hospitals to home with home health.

Science.gov (United States)

Smith, Shannon Bright; Alexander, Judith W

2012-01-01

The study's purpose was to determine nurses' opinions of sending patients from the hospital to home with home health services. The study occurred in the Charleston, South Carolina, Tricounty area (Berkeley, Charleston, and Dorchester counties). Home health agencies and hospitals were invited to participate. The study used a survey design to gather information on nursing perceptions of current practices and needed changes to improve transition of patients. The population was nurses (licensed practical nurses (LPNs) and registered nurses (RNs)) employed at inpatient hospitals or home health agencies in the area. Thirty-four RNs responded with no LPNs respondents. Agency administrators/chief nursing officers agreed for their agencies to participate and distributed the survey using a Research Electronic Data Capture (REDCap) Internet-based survey tool. Using the survey results and information from a literature review, the study developed a list of propositions, which participating administrators reviewed, for improving transitions to home. Both home health and hospital nurses reported a need to improve the process of sending patients from hospital to home with home health services. This study provides hospitals and home health agencies with propositions to facilitate the establishment of a process to communicate effectively patients care needs and streamline the discharging patients from the hospital to home health care; thus, improving patient transition. Case managers and discharge planners will need interagency collaboration along with evidence-based interventions to transition patients from the hospital to home with home health services with various populations. Direct patient care nurses in both hospital and home health settings should share the same accountability as case managers to ensure successful transitions.

Beyond war and PTSD: The crucial role of transition stress in the lives of military veterans.

Science.gov (United States)

Mobbs, Meaghan C; Bonanno, George A

2018-02-01

Although only a relatively small minority of military veterans develop Posttraumatic Stress Disorder (PTSD), mental health theory and research with military veterans has focused primarily on PTSD and its treatment. By contrast, many and by some accounts most veterans experience high levels of stress during the transition to civilian life, however transition stress has received scant attention. In this paper we attempt to address this deficit by reviewing the wider range of challenges, rewards, successes, and failures that transitioning veterans might experience, as well as the factors that might moderate these experiences. To illuminate this argument, we briefly consider what it means to become a soldier (i.e., what is required to transition into military service) and more crucially what kind of stressors veterans might experience when they attempt to shed that identity (i.e., what is required to transition out of military service). We end by suggesting how an expanded research program on veteran transition stress might move forward. Copyright © 2017 Elsevier Ltd. All rights reserved.

The influence of service planning decisions on rail transit success or failure.

Science.gov (United States)

2009-06-01

Some United States metropolitan areas with rail transit systems enjoy ridership and productivity success while : others do not. This study examines the experiences of 11 U.S. metropolitan areas with between onr million and : five million persons to b...

"The Day All of the Different Parts of Me Can Come Along": Intersectionality and U.S. Third World Feminism in the Poetry of Pat Parker and Willyce Kim.

Science.gov (United States)

Van Ausdall, Mimi Iimuro

2015-01-01

This article brings to light the poetry of Pat Parker and Willyce Kim, two key figures within the 1970s and '80s women in print movement. While Parker and Kim have been rightly placed within African-American and Asian-American histories, respectively, and working-class and lesbian-feminist literary histories, their work is most fully understood within the context of U.S. Third World Feminism. Through close readings of poetic form and content in addition to engagement with current debates about intersectionality as a methodology, the article links Kim and Parker's works to central contributions of U.S. Third World Feminism such as intersectionality and power across and within difference that continue to influence feminist theory today.

Combining microwave resonance technology to multivariate data analysis as a novel PAT tool to improve process understanding in fluid bed granulation.

Science.gov (United States)

Lourenço, Vera; Herdling, Thorsten; Reich, Gabriele; Menezes, José C; Lochmann, Dirk

2011-08-01

A set of 192 fluid bed granulation batches at industrial scale were in-line monitored using microwave resonance technology (MRT) to determine moisture, temperature and density of the granules. Multivariate data analysis techniques such as multiway partial least squares (PLS), multiway principal component analysis (PCA) and multivariate batch control charts were applied onto collected batch data sets. The combination of all these techniques, along with off-line particle size measurements, led to significantly increased process understanding. A seasonality effect could be put into evidence that impacted further processing through its influence on the final granule size. Moreover, it was demonstrated by means of a PLS that a relation between the particle size and the MRT measurements can be quantitatively defined, highlighting a potential ability of the MRT sensor to predict information about the final granule size. This study has contributed to improve a fluid bed granulation process, and the process knowledge obtained shows that the product quality can be built in process design, following Quality by Design (QbD) and Process Analytical Technology (PAT) principles. Copyright © 2011. Published by Elsevier B.V.

Meeting the Needs of the Hidden Minority: Transition Planning Tips for LGBTQ Youth

Science.gov (United States)

Dykes, Frank; Thomas, Suzanne

2015-01-01

Effective transition planning requires school personnel to ascertain the preferences and interests of the student and to focus on services including instruction, related services, employment, and postschool living arrangements necessary to support postschool outcomes. While great strides have been made in meeting the needs of students with…

Functional Assessment in Transition and Rehabilitation for Adolescents and Adults with Learning Disorders.

Science.gov (United States)

Bullis, Michael, Ed.; Davis, Cheryl D., Ed.

This manual is based on a 3-year, federally funded program, Project FASTER (Functional Assessment Services for Transition, Education, and Rehabilitation), that developed functional assessment procedures and provided assessment services to adolescents and adults with learning or behavioral disorders who were involved in school-based transition…

Investigating the In-Vehicle Crowding Cost Functions for Public Transit Modes

OpenAIRE

Qin, Feifei

2014-01-01

In the densely populated metropolitan area, empirical studies have found that overcrowding inside transit vehicles has become substantially worse and worse over recent years. Chronic in-vehicle crowding is not only caused by a lack of physical infrastructure, but also triggered by inadequate service provisions. Given the prevalence of overcrowded transit vehicles, this paper conducts both quantitative and qualitative studies, especially focusing on remodeling the in-vehicle crowding cost func...

A Report on the Navy SBIR Program: Best Practices, Roadblocks and Recommendations for Technology Transition

National Research Council Canada - National Science Library

Bland, Erin; Busch, Dan; Clark, Al

2008-01-01

Over the past few years the Armed Services Committees have shown an increased interest in the DoD doing as much as possible to transition SBIR developed technologies into products or services that support the warfighter...

Multi-professional communication for older people in transitional care: a review of the literature.

Science.gov (United States)

Allen, Jacqui; Ottmann, Goetz; Roberts, Gail

2013-12-01

To synthesise research-reporting literature about multi-professional communication between health and social care professionals within transitional care for older people, with particular attention on outcomes, enabling contextual factors and constraints. Older adults experience high rates of morbidity and health care usage, and frequently transit between health services, and community and social care providers. These transition episodes place elders at increased risk of adverse incidents due to poor communication of information. Integrated multi-professional models of care built on enhanced communication have been widely promoted as a strategy to improve transitional care for older people. However, a range of findings exist in the literature to guide service providers and researchers. Comprehensive literature search and review strategies were employed to identify, describe and synthesise relevant studies. Ten databases were searched in addition to Google Scholar. Specified discharge worker roles, multi-professional care coordination teams, and information technology systems promote better service satisfaction and subjective quality of life for older people when compared with standard hospital discharge. Improved multi-professional communication reduces rates of re-admission and length of stay indicating greater cost effectiveness and efficiency for the health and social care systems. Systems of care emphasizing information exchange, education and negotiation between stakeholders facilitate communication in transitional care contexts for older adults. Conversely, lack of dialogue and lack of understanding of others' roles are barriers to communication in transitional care. Enhanced multi-professional communication, transitional pathways, and role clarity are required to improve the quality, sustainability and responsiveness of aged care into the future. Recommendations for further research include: (i) Investigation of pathways promoting person-centred care planning

Moving On: Transitions for Youth with Behavioral Disorders. Working with Behavioral Disorders: CEC Mini-Library.

Science.gov (United States)

Bullis, Michael; Gaylord-Ross, Robert

This booklet reviews the literature on transitional services for youth with behavior disorders, provides examples of successful programs and activities, and identifies key elements of successful programs. Specific sections of the monograph address the following areas: long-term life adjustment; transition studies; vocational assessment; social…

Limitations of existing web services

Indian Academy of Sciences (India)

First page Back Continue Last page Overview Graphics. Limitations of existing web services. Uploading or downloading large data. Serving too many user from single source. Difficult to provide computer intensive job. Depend on internet and its bandwidth. Security of data in transition. Maintain confidentiality of data ...

Portāla YouTube patēriņa paradumi un lietošanas motivācija vidusskolas vecuma jauniešu vidū

OpenAIRE

Krastiņa, Lāsma

2016-01-01

Bakalaura darba „Portāla Youtube patēriņa paradumi un lietošanas motivācija vidusskolas vecuma jauniešu vidū” mērķis ir veicot padziļinātās intervijas un anketēšanu noskaidrot kādām darbībām portāls Youtube galvenokārt tiek izmantots un kādi ir tā izmantošanas paradumi un motivācija Latvijas vidusskolas vecuma jauniešu vidū. Darbs sastāv no 7 nodaļām. Teorētisko daļu sastāda nodaļas par Web 2.0, portālu Youtube, lietojuma un apmierinātības teoriju, bērnu un jauniešu interneta lietojumu. Metod...

34 CFR 303.148 - Transition to preschool programs.

Science.gov (United States)

2010-07-01

... 34 Education 2 2010-07-01 2010-07-01 false Transition to preschool programs. 303.148 Section 303.148 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION EARLY INTERVENTION PROGRAM FOR INFANTS AND TODDLERS WITH DISABILITIES State...

Physicians' perceptions about the quality of primary health care services in transitional Albania

NARCIS (Netherlands)

Kellici, Neritan; Dibra, Arvin; Mihani, Joana; Kellici, Suela; Burazeri, Genc

AIM: To date, the available information regarding the quality of primary health care services in Albania is scarce. The aim of our study was to assess the quality of primary health care services in Albania based on physicians' perceptions towards the quality of the services provided to the general

Health system strategies supporting transition to adult care.

Science.gov (United States)

Hepburn, Charlotte Moore; Cohen, Eyal; Bhawra, Jasmin; Weiser, Natalie; Hayeems, Robin Z; Guttmann, Astrid

2015-06-01

The transition from paediatric to adult care is associated with poor clinical outcomes, increased costs and low patient and family satisfaction. However, little is known about health system strategies to streamline and safeguard care for youth transitioning to adult services. Moreover, the needs of children and youth are often excluded from broader health system reform discussions, leaving this population especially vulnerable to system 'disintegration'. (1) To explore the international policy profile of paediatric-to-adult care transitions, and (2) to document policy objectives, initiatives and outcomes for jurisdictions publicly committed to addressing transition issues. An international policy scoping review of all publicly available government documents detailing transition-related strategies was completed using a web-based search. Our analysis included a comparable cohort of nine wealthy Organisation for Economic Co-operation and Development (OECD) jurisdictions with Beveridge-style healthcare systems (deemed those most likely to benefit from system-level transition strategies). Few jurisdictions address transition of care issues in either health or broader social policy documents. While many jurisdictions refer to standardised practice guidelines, a few report the intention to use powerful policy levers (including physician remuneration and non-physician investments) to facilitate the uptake of best practice. Most jurisdictions do not address the policy infrastructure required to support successful transitions, and rigorous evaluations of transition strategies are rare. Despite the well-documented risks and costs associated with a poor transition from paediatric to adult care, little policy attention has been paid to this issue. We recommend that healthcare providers engage health system planners in the design and evaluation of system-level, policy-sensitive transition strategies. Published by the BMJ Publishing Group Limited. For permission to use (where not

The Search for Quality by Management in Service-Related Industry Today

Science.gov (United States)

1988-09-05

Lagaz f te touferConoirse Hotel - Los items as scalloped sevtche, avocado and torr 010 LAnele ofthrses in lelrat Safoo iith shrimp, smoked salmon...Contracts/ export orders 10M 4:00 p.m. Sales School I Presentation March 22, 1988 8:15 a.m. Pat Hanneken - Lakeside OTC Team overview (discussions on ASR

Autism spectrum disorder in adults: diagnosis, management, and health services development

Science.gov (United States)

Murphy, Clodagh M; Wilson, C Ellie; Robertson, Dene M; Ecker, Christine; Daly, Eileen M; Hammond, Neil; Galanopoulos, Anastasios; Dud, Iulia; Murphy, Declan G; McAlonan, Grainne M

2016-01-01

Autism spectrum disorder (ASD) is a common neurodevelopmental disorder characterized by pervasive difficulties since early childhood across reciprocal social communication and restricted, repetitive interests and behaviors. Although early ASD research focused primarily on children, there is increasing recognition that ASD is a lifelong neurodevelopmental disorder. However, although health and education services for children with ASD are relatively well established, service provision for adults with ASD is in its infancy. There is a lack of health services research for adults with ASD, including identification of comorbid health difficulties, rigorous treatment trials (pharmacological and psychological), development of new pharmacotherapies, investigation of transition and aging across the lifespan, and consideration of sex differences and the views of people with ASD. This article reviews available evidence regarding the etiology, legislation, diagnosis, management, and service provision for adults with ASD and considers what is needed to support adults with ASD as they age. We conclude that health services research for adults with ASD is urgently warranted. In particular, research is required to better understand the needs of adults with ASD, including health, aging, service development, transition, treatment options across the lifespan, sex, and the views of people with ASD. Additionally, the outcomes of recent international legislative efforts to raise awareness of ASD and service provision for adults with ASD are to be determined. Future research is required to identify high-quality, evidence-based, and cost-effective models of care. Furthermore, future health services research is also required at the beginning and end of adulthood, including improved transition from youth to adult health care and increased understanding of aging and health in older adults with ASD. PMID:27462160

Transition costs in the electricity industry: A summary of issues

Energy Technology Data Exchange (ETDEWEB)

Baxter, L.; Hirst, E.; Hadley, S.

1996-10-01

Progress is evident as the restructuring debate in the U.S. electricity industry completes its third year. The Federal Energy Regulatory Commission released a final rule on transmission open access-a key element to facilitate more efficient wholesale markets. The majority of states have initiated investigations or discussions on restructuring retail markets. Yet hurdles remain in formulating and implementing state-level restructuring proposals. Perhaps foremost among these hurdles is the issue of transition costs (the potential monetary losses experienced by utilities, consumers, and other economic actors as a result of government initiatives to transform electricity generation from a regulated to a competitive market). Transition costs are approximately equal to the difference between the embedded cost for generation services under traditional cost-of-service regulation and the competitive-market price for power. When government takes action to open current monopoly franchises to multiple generation providers and the competitive-market price falls below embedded generation costs, then transition costs will arise. Transition costs will include one or more of the following four classes of costs: (1) assets, primarily utility-owned power plants; (2) liabilities, primarily long-term power-purchase and fuel-supply contracts; (3) regulatory assets, including deferred expenses and costs that regulators allow utilities to place on their balance sheets; and (4) public-policy programs, such as energy efficiency, low-income programs, and research and development. What is at issue in the transition-cost debate? The debate turns on four questions: (1) How large are the potential transition costs from restructuring? (2) How are these costs estimated? (3) What, if anything, might be done to address these costs? (4) Who will ultimately pay for any remaining costs and how? This paper summarizes some of the key results from a project at ORNL that addresses these four questions.

Managing innovation systems in transition economies

OpenAIRE

Baković, Tomislav

2010-01-01

Successfully managing innovations has become the basic precondition for the development of both companies and national economies. At the national level governments are forming innovation systems whose primary goal is to create conditions at which science and technology can flourish and then transfer their findings trough private sector into new revolutionary products and services. Unfortunately not all countries have the same preconditions for creating such systems and transition economies du...

Maltreatment, family environment, and social risk factors: Determinants of the child welfare to juvenile justice transition among maltreated children and adolescents.

Science.gov (United States)

Vidal, Sarah; Prince, Dana; Connell, Christian M; Caron, Colleen M; Kaufman, Joy S; Tebes, Jacob K

2017-01-01

This study prospectively examines the transition from the child welfare system into the juvenile justice system among 10,850 maltreated children and adolescents and explores how patterns of risks, including severity and chronicity of maltreatment, adverse family environment, and social risk factors, affect service systems transition. Almost three percent of maltreated children and adolescents had their first juvenile justice adjudication within an average of approximately six years of their initial child protective services investigation (CPS). Social risk factors, including a child's age at index CPS investigation (older), gender (boys), and race/ethnicity (Black and Hispanic) significantly predicted the risk of transition into the juvenile justice system. Recurrence of maltreatment and experiencing at least one incident of neglect over the course of the study period also increased the risk of transition into the juvenile justice system. However, subtypes of maltreatment, including physical, sexual, and other types of abuse did not significantly predict the risk of juvenile justice system transition. Finally, family environment characterized by poverty also significantly increased the risk of juvenile justice system transition. These findings have important implications for developing and tailoring services for maltreated children, particularly those at-risk for transitioning into the juvenile justice system. Copyright © 2016 Elsevier Ltd. All rights reserved.

Current Challenges Facing Secondary Education and Transition Services: What Research Tells Us.

Science.gov (United States)

Johnson, David R.; Stodden, Robert A.; Emanuel, Ellen J.; Luecking, Richard; Mack, Mary

2002-01-01

The transition challenges discussed are to ensure that (1) students have access to the full range of curriculum options and learning experiences; (2) high school graduation decisions are based on meaningful indicators of learning; (3) students have access to postsecondary education, employment, and independent living options; (4) student and…

An Exploration of Transition Experiences Shaping Student Veteran Life Flow

Science.gov (United States)

Gregg, Brian Tuan

2016-01-01

Educational institutions offer transformative opportunities for veterans transitioning from military service. Veteran-specific cultural supports in educational environments offer participation in occupations and development of skills needed to complete educational goals. However, veterans experience complex life circumstances atypical from…

Multi-parameter flow cytometry as a process analytical technology (PAT) approach for the assessment of bacterial ghost production.

Science.gov (United States)

Langemann, Timo; Mayr, Ulrike Beate; Meitz, Andrea; Lubitz, Werner; Herwig, Christoph

2016-01-01

Flow cytometry (FCM) is a tool for the analysis of single-cell properties in a cell suspension. In this contribution, we present an improved FCM method for the assessment of E-lysis in Enterobacteriaceae. The result of the E-lysis process is empty bacterial envelopes-called bacterial ghosts (BGs)-that constitute potential products in the pharmaceutical field. BGs have reduced light scattering properties when compared with intact cells. In combination with viability information obtained from staining samples with the membrane potential-sensitive fluorescent dye bis-(1,3-dibutylarbituric acid) trimethine oxonol (DiBAC4(3)), the presented method allows to differentiate between populations of viable cells, dead cells, and BGs. Using a second fluorescent dye RH414 as a membrane marker, non-cellular background was excluded from the data which greatly improved the quality of the results. Using true volumetric absolute counting, the FCM data correlated well with cell count data obtained from colony-forming units (CFU) for viable populations. Applicability of the method to several Enterobacteriaceae (different Escherichia coli strains, Salmonella typhimurium, Shigella flexneri 2a) could be shown. The method was validated as a resilient process analytical technology (PAT) tool for the assessment of E-lysis and for particle counting during 20-l batch processes for the production of Escherichia coli Nissle 1917 BGs.

Rural and urban transit district benchmarking : effectiveness and efficiency guidance document.

Science.gov (United States)

2011-05-01

Rural and urban transit systems have sought ways to compare performance across agencies, : identifying successful service delivery strategies and applying these concepts to achieve : successful results within their agency. Benchmarking is a method us...

The Impact of Professional Development on the Quality of the Transition Components of IEPs

Science.gov (United States)

Flannery, K. Brigid; Lombardi, Allison; Kato, Mimi McGrath

2015-01-01

Under the Individuals With Disabilities Education Act (IDEA), transition needs and services are to be discussed as part of the Individual Education Program (IEP) planning process, and decisions based on students' future goals are to be documented in the IEP. These transition requirements were included in IDEA in order to plan with the student,…

Challenges of modern day transition care in inflammatory bowel disease: From inflammatory bowel disease to biosimilars.

Science.gov (United States)

Hakizimana, Ali; Ahmed, Iftikhar; Russell, Rachel; Wright, Mark; Afzal, Nadeem A

2017-07-07

In this article we discuss the challenges of delivering a high quality Transition care. A good understanding of the adolescent needs with good communication between Transition care physicians and the patient is essential for good continuity of care. Despite availability of several guidelines, one model doesn't fit all and any transition service development should be determined by the local need and available healthcare facilities.

Impact of the Transition to ICD-10 on Medicare Payment

Data.gov (United States)

U.S. Department of Health & Human Services — Although the transition from the ICD-9-CM to the ICD-10 version of MS-DRGs resulted in 1.68 percent of the patients being assigned to a different MS-DRG, payment...

Talent 2 - the new vehicle family for regional and rapid transit rail services; Talent 2 - Die neue Fahrzeugfamilie fuer den Regional- und S-Bahnverkehr

Energy Technology Data Exchange (ETDEWEB)

Segieth, Christian [Bombardier Transportation, Hennigsdorf (Germany)

2008-07-01

In February 2007, Deutsche Bahn AG concluded a framework contract with railway vehicle manufacturer Bombardier for the supply of 321 new-generation Talent 2 electrical multiple unit trains for regional and rapid transit rail services. In light of changing market requirements, the trains are not being delivered in predetermined numbers at predetermined dates, as used to be customary, but will be released according to need up until 2014. The contract covers the basic conditions and agreements for the overall order, which is worth some 1.2 billion of Euros. Deutsche Bahn AG has already concluded similar contracts with Bombardier for double-deck coaches. (orig.)

Technical developments in international satellite business services

Science.gov (United States)

Tan, P. P.

At the conception of International Satellite Business Services (ISBS), it was a primary objective to provide flexibility for accommodating a variety of service requirements which might be established by mutual agreement between users. The design guidelines are to ensure that the space segment is efficiently utilized, while other satellite services are protected from interference. Other considerations are related to an acceptable earth segment cost, maximum connectivity in worldwide services, the capability of growth and a reasonably smooth transition into future systems, and the maintenance of high performance objectives. Attention is given to a system overview, the characteristics of satellites for ISBS, and technological developments with some application possibilities for ISBS.

Leveraging Service Oriented Architecture to Enhance Information Sharing for Surface Transportation Security

Science.gov (United States)