WorldWideScience

Sample records for traditional research approaches

  1. A Quantitative Proteomics Approach to Clinical Research with Non-Traditional Samples

    Directory of Open Access Journals (Sweden)

    Rígel Licier

    2016-10-01

    Full Text Available The proper handling of samples to be analyzed by mass spectrometry (MS can guarantee excellent results and a greater depth of analysis when working in quantitative proteomics. This is critical when trying to assess non-traditional sources such as ear wax, saliva, vitreous humor, aqueous humor, tears, nipple aspirate fluid, breast milk/colostrum, cervical-vaginal fluid, nasal secretions, bronco-alveolar lavage fluid, and stools. We intend to provide the investigator with relevant aspects of quantitative proteomics and to recognize the most recent clinical research work conducted with atypical samples and analyzed by quantitative proteomics. Having as reference the most recent and different approaches used with non-traditional sources allows us to compare new strategies in the development of novel experimental models. On the other hand, these references help us to contribute significantly to the understanding of the proportions of proteins in different proteomes of clinical interest and may lead to potential advances in the emerging field of precision medicine.

  2. A Quantitative Proteomics Approach to Clinical Research with Non-Traditional Samples.

    Science.gov (United States)

    Licier, Rígel; Miranda, Eric; Serrano, Horacio

    2016-10-17

    The proper handling of samples to be analyzed by mass spectrometry (MS) can guarantee excellent results and a greater depth of analysis when working in quantitative proteomics. This is critical when trying to assess non-traditional sources such as ear wax, saliva, vitreous humor, aqueous humor, tears, nipple aspirate fluid, breast milk/colostrum, cervical-vaginal fluid, nasal secretions, bronco-alveolar lavage fluid, and stools. We intend to provide the investigator with relevant aspects of quantitative proteomics and to recognize the most recent clinical research work conducted with atypical samples and analyzed by quantitative proteomics. Having as reference the most recent and different approaches used with non-traditional sources allows us to compare new strategies in the development of novel experimental models. On the other hand, these references help us to contribute significantly to the understanding of the proportions of proteins in different proteomes of clinical interest and may lead to potential advances in the emerging field of precision medicine.

  3. Comparing Two Survey Research Approaches: E-Mail and Web-Based Technology versus Traditional Mail.

    Science.gov (United States)

    Howes, Colleen M.; Mailloux, Mark R.

    2001-01-01

    Contrasted two survey methodologies: e-mail-Web and traditional mail. Found that: (1) e-mail-Web respondents were proportionately more likely to be male and enrolled in school full-time; (2) more individual question non-response was present for the e-mail-Web sample; and (3) e-mail-Web respondents value different aspects of graduate school. (EV)

  4. Infusing Qualitative Traditions in Counseling Research Designs

    Science.gov (United States)

    Hays, Danica G.; Wood, Chris

    2011-01-01

    Research traditions serve as a blueprint or guide for a variety of design decisions throughout qualitative inquiry. This article presents 6 qualitative research traditions: grounded theory, phenomenology, consensual qualitative research, ethnography, narratology, and participatory action research. For each tradition, the authors describe its…

  5. A systems approach to traditional oriental medicine

    DEFF Research Database (Denmark)

    Kim, Hyun Uk; Ryu, Jae Yong; Lee, Jong Ok

    2015-01-01

    Analyzing structural similarities between compounds derived from traditional oriental medicine and human metabolites is a systems-based approach that can help identify mechanisms of action and suggest approaches to reduce toxicity.......Analyzing structural similarities between compounds derived from traditional oriental medicine and human metabolites is a systems-based approach that can help identify mechanisms of action and suggest approaches to reduce toxicity....

  6. Staff competence in dealing with traditional approaches

    DEFF Research Database (Denmark)

    Kastrup, M.

    2008-01-01

    backgrounds of patients there is a need for mental health professionals to recognize the existence of traditional approaches and be aware of the parallel systems of care. Competent treatment of such patients requires that mental health professionals are aware of this and exhibit a willingness and ability...... to bridge between the more traditional and the Western approaches to treatment. The delineations and various aspects of the concept cultural competence and its dimensions will be discussed from a clinical perspective. Comparative studies of the various Western and the traditional approaches respectively...

  7. Benevolent Paradox: Integrating Community-Based Empowerment and Transdisciplinary Research Approaches into Traditional Frameworks to Increase Funding and Long-Term Sustainability of Chicano-Community Research Programs

    Science.gov (United States)

    de la Torre, Adela

    2014-01-01

    Niños Sanos, Familia Sana (NSFS) is a 5-year multi-intervention study aimed at preventing childhood obesity among Mexican-origin children in rural California. Using a transdisciplinary approach and community-based participatory research (CBPR) methodology, NSFS's development included a diversely trained team working in collaboration with community…

  8. Genetic Bases of Bicuspid Aortic Valve: The Contribution of Traditional and High-Throughput Sequencing Approaches on Research and Diagnosis.

    Science.gov (United States)

    Giusti, Betti; Sticchi, Elena; De Cario, Rosina; Magi, Alberto; Nistri, Stefano; Pepe, Guglielmina

    2017-01-01

    development of "BigData" analysis methods improving their interpretation and integration with clinical data represents a promising opportunity to increase the disease knowledge and diagnosis in monogenic and multifactorial complex traits. This review summarized the main knowledge on the BAV genetic bases, the role of genetic diagnosis in BAV patient managements and the crucial challenges for the comprehension of genetics of BAV in research and diagnosis.

  9. Genetic Bases of Bicuspid Aortic Valve: The Contribution of Traditional and High-Throughput Sequencing Approaches on Research and Diagnosis

    Directory of Open Access Journals (Sweden)

    Betti Giusti

    2017-08-01

    the development of “BigData” analysis methods improving their interpretation and integration with clinical data represents a promising opportunity to increase the disease knowledge and diagnosis in monogenic and multifactorial complex traits. This review summarized the main knowledge on the BAV genetic bases, the role of genetic diagnosis in BAV patient managements and the crucial challenges for the comprehension of genetics of BAV in research and diagnosis.

  10. Demystifying traditional herbal medicine with modern approach.

    Science.gov (United States)

    Li, Fu-Shuang; Weng, Jing-Ke

    2017-07-31

    Plants have long been recognized for their therapeutic properties. For centuries, indigenous cultures around the world have used traditional herbal medicine to treat a myriad of maladies. By contrast, the rise of the modern pharmaceutical industry in the past century has been based on exploiting individual active compounds with precise modes of action. This surge has yielded highly effective drugs that are widely used in the clinic, including many plant natural products and analogues derived from these products, but has fallen short of delivering effective cures for complex human diseases with complicated causes, such as cancer, diabetes, autoimmune disorders and degenerative diseases. While the plant kingdom continues to serve as an important source for chemical entities supporting drug discovery, the rich traditions of herbal medicine developed by trial and error on human subjects over thousands of years contain invaluable biomedical information just waiting to be uncovered using modern scientific approaches. Here we provide an evolutionary and historical perspective on why plants are of particular significance as medicines for humans. We highlight several plant natural products that are either in the clinic or currently under active research and clinical development, with particular emphasis on their mechanisms of action. Recent efforts in developing modern multi-herb prescriptions through rigorous molecular-level investigations and standardized clinical trials are also discussed. Emerging technologies, such as genomics and synthetic biology, are enabling new ways for discovering and utilizing the medicinal properties of plants. We are entering an exciting era where the ancient wisdom distilled into the world's traditional herbal medicines can be reinterpreted and exploited through the lens of modern science.

  11. Traditional machining processes research advances

    CERN Document Server

    2015-01-01

    This book collects several examples of research in machining processes. Chapter 1 provides information on polycrystalline diamond tool material and its emerging applications. Chapter 2 is dedicated to the analysis of orthogonal cutting experiments using diamond-coated tools with force and temperature measurements. Chapter 3 describes the estimation of cutting forces and tool wear using modified mechanistic models in high performance turning. Chapter 4 contains information on cutting under gas shields for industrial applications. Chapter 5 is dedicated to the machinability of magnesium and its alloys. Chapter 6 provides information on grinding science. Finally, chapter 7 is dedicated to flexible integration of shape and functional modelling of machine tool spindles in a design framework.    

  12. Comparison of Traditional and Constructivist Teaching Approaches ...

    African Journals Online (AJOL)

    The second section of students had 47 students and was taught using traditional teaching approach. Learning strategy inventory questionnaire which was adapted from strategy inventory for language learning (SILL) L2 students of English, (Oxford, 1990) was employed before and after students were taught using two ...

  13. The ethics of improving African traditional medical practice: scientific or African traditional research methods?

    Science.gov (United States)

    Nyika, Aceme

    2009-11-01

    The disease burden in Africa, which is relatively very large compared with developed countries, has been attributed to various factors that include poverty, food shortages, inadequate access to health care and unaffordability of Western medicines to the majority of African populations. Although for 'old diseases' knowledge about the right African traditional medicines to treat or cure the diseases has been passed from generation to generation, knowledge about traditional medicines to treat newly emerging diseases has to be generated in one way or another. In addition, the existing traditional medicines have to be continuously improved, which is also the case with Western scientific medicines. Whereas one school of thought supports the idea of improving medicines, be they traditional or Western, through scientific research, an opposing school of thought argues that subjecting African traditional medicines to scientific research would be tantamount to some form of colonization and imperialism. This paper argues that continuing to use African traditional medicines for old and new diseases without making concerted efforts to improve their efficacy and safety is unethical since the disease burden affecting Africa may continue to rise in spite of the availability and accessibility of the traditional medicines. Most importantly, the paper commends efforts being made in some African countries to improve African traditional medicine through a combination of different mechanisms that include the controversial approach of scientific research on traditional medicines.

  14. Research traditions and evolutionary explanations in medicine.

    Science.gov (United States)

    Méthot, Pierre-Olivier

    2011-02-01

    In this article, I argue that distinguishing 'evolutionary' from 'Darwinian' medicine will help us assess the variety of roles that evolutionary explanations can play in a number of medical contexts. Because the boundaries of evolutionary and Darwinian medicine overlap to some extent, however, they are best described as distinct 'research traditions' rather than as competing paradigms. But while evolutionary medicine does not stand out as a new scientific field of its own, Darwinian medicine is united by a number of distinctive theoretical and methodological claims. For example, evolutionary medicine and Darwinian medicine can be distinguished with respect to the styles of evolutionary explanations they employ. While the former primarily involves 'forward looking' explanations, the latter depends mostly on 'backward looking' explanations. A forward looking explanation tries to predict the effects of ongoing evolutionary processes on human health and disease in contemporary environments (e.g., hospitals). In contrast, a backward looking explanation typically applies evolutionary principles from the vantage point of humans' distant biological past in order to assess present states of health and disease. Both approaches, however, are concerned with the prevention and control of human diseases. In conclusion, I raise some concerns about the claim that 'nothing in medicine makes sense except in the light of evolution'.

  15. Populism in Lithuania: defining the research tradition

    OpenAIRE

    Aleknonis, Gintaras; Matkevičienė, Renata

    2016-01-01

    The research on populism and populist political communication in Lithuania is rather limited, regardless of the fact that populist movements and politicians are influential on national and local political levels; they also receive sufficient support from a significant share of the population. Because the Western European research tradition is concentrated on the challenges of right-wing populism, Lithuanian political scientists distinguish right-wing populism as more significant in comparison...

  16. Populism in Lithuania: Defining the Research Tradition

    Directory of Open Access Journals (Sweden)

    Aleknonis Gintaras

    2016-06-01

    Full Text Available The research on populism and populist political communication in Lithuania is rather limited, regardless of the fact that populist movements and politicians are influential on national and local political levels; they also receive sufficient support from a significant share of the population. Because the Western European research tradition is concentrated on the challenges of right-wing populism, Lithuanian political scientists distinguish right-wing populism as more significant in comparison to left-wing populism. Although Lithuanian researchers note, that in the balance of the left-right wing populists, Lithuania stands out with the majority of left-wing populists, in comparison to the popularity and number of right-wing populists in neighbouring countries.

  17. Ethnobotanical approaches of traditional medicine studies: some experiences from Asia.

    Science.gov (United States)

    Sheng-Ji, P

    2001-01-01

    Ethnobotany, as a research field of science, has been widely used for the documentation of indigenous knowledge on the use of plants and for providing an inventory of useful plants from local flora in Asian countries. Plants that are used for traditional herbal medicine in different countries are an important part of these studies. However, in some countries in recent years, ethnobotanical studies have been used for the discovery of new drugs and new drug development. In general, experiences gained from ethnobotanical approaches of traditional medicinal studies in China and Himalayan countries have helped drug production and new drug development. At the same time, in many cases, over-harvesting, degradation of medical plants, and loss of traditional medical knowledge in local communities are common problems in these resource areas. Issues of indigenous knowledge, intellectual property rights, and uncontrolled transboundary trade in medicinal plants occur frequently in the region. This paper discusses ethnobotanical approaches of traditional medicinal studies, in reference to experiences from China and Himalayan countries, with an emphasis on the conservation of traditional medical knowledge and medical plant resources.

  18. Chinese Traditional Philosophy and Indigenous Management Research

    DEFF Research Database (Denmark)

    Li, Xin

    2013-01-01

    This paper focuses on three key notions of Chinese traditional philosophy, i.e., Zhongyong, Yin Yang, and Wu, pointing out the possible mistakes in Prof. Peter Ping Li's arguments as well as some questions that are often neglected and taken for granted. The author posits, Chinese traditional...... philosophy is a system of thought distinct from the Western philosophy; while the Western philosophy is mainly concerned about the True, i.e., the objective knowledge of the world, the aim of Chinese traditional philosophy is the pursuit of the Good, i.e., the unification of heaven and human....

  19. Feminist Critiques Against Traditional Approaches to Security

    NARCIS (Netherlands)

    Petrus Kanisius Farneubun, P.

    Feminists claim that national security is a model of masculinity domination, which hardly disputed This essay addresses feminists critique on notion of conventional security and provides feminists own definition. It shows that feminists adopt comprehensive approach in relation to security. They tend

  20. Tradition

    DEFF Research Database (Denmark)

    Otto, Ton

    2016-01-01

    : beliefs, practices, institutions, and also things. In this sense, the meaning of the term in social research is very close to its usage in common language and is not always theoretically well developed (see Shils, 1971: 123). But the concept of tradition has also been central to major theoretical debates...... on the nature of social change, especially in connection with the notion of modernity. Here tradition is linked to various forms of agency as a factor of both stability and intentional change....

  1. Traditional, complementary, and alternative medicine: Focusing on research into traditional Tibetan medicine in China.

    Science.gov (United States)

    Song, Peipei; Xia, Jufeng; Rezeng, Caidan; Tong, Li; Tang, Wei

    2016-07-19

    As a form of traditional, complementary, and alternative medicine (TCAM), traditional Tibetan medicine has developed into a mainstay of medical care in Tibet and has spread from there to China and then to the rest of the world. Thus far, research on traditional Tibetan medicine has focused on the study of the plant and animal sources of traditional medicines, study of the histology of those plants and animals, chemical analysis of traditional medicines, pharmacological study of those medicines, and evaluation of the clinical efficacy of those medicines. A number of papers on traditional Tibetan medicines have been published, providing some evidence of the efficacy of traditional Tibetan medicine. However, many traditional Tibetan medicines have unknown active ingredients, hampering the establishment of drug quality standards, the development of new medicines, commercial production of medicines, and market availability of those medicines. Traditional Tibetan medicine must take several steps to modernize and spread to the rest of the world: the pharmacodynamics of traditional Tibetan medicines need to be determined, the clinical efficacy of those medicines needs to be verified, criteria to evaluate the efficacy of those medicines need to be established in order to guide their clinical use, and efficacious medicines need to be acknowledged by the pharmaceutical market. The components of traditional Tibetan medicine should be studied, traditional Tibetan medicines should be screened for their active ingredients, and techniques should be devised to prepare and manufacture those medicines.

  2. Herbal Medicines: from Traditional Medicine to Modern Experimental Approaches

    Directory of Open Access Journals (Sweden)

    Bahram Rasoulian

    2017-03-01

    Full Text Available Academic writings indicate that the medicinal use of plants dates back to 4000 - 5000 B.C. (1. Utilization of medicinal herbs has indeed a long history not only in human's life, but also in animals and there are some interesting evidences about the animals' self-medication, in both the prevention and treatment of diseases (2-5. The World Health Organization (WHO has recognized the importance of traditional medicines and created strategies, guidelines and standards for botanical medicines (6, 7. A significant part of those traditional text dealing with medicine, which were appreciated by ancient scientific communities worldwide, such as The Canon of Medicine by Persian physician–philosopher Ibn Sina (or Avicenna, 980 to 1032 AD, is allocated to herbal medicines. The Canon explores nearly 500 medicinal plants and herbal drugs. It should be noted that this book was used as a medical textbook in Europe until the 17th century AD (8, 9. Although there are important evidences about using some kinds of experimental approaches in traditional medicine (8, the efficacy of such approaches is in doubt because it is generally agreed that they might have been part of physicians' personal experiences. Not only the demand for herbal drugs is growing in developing countries, but also there are some evidences that consumers in developed countries are becoming disillusioned with modern healthcare; hence, the demand for traditional alternatives including herbal medicines is increasing in developing countries (10. On the one hand, the increased interest in herbal medicines throughout the world (10, 11, on the other hand, the need for direct empirical evidence about the effectiveness of herbal medicines in the proper statistical society with the appropriate number and method, denote the significance of new studies about medicinal plants and publishing their results. Herbal Medicines Journal (eISSN: 2538-2144 reports valuable research results for researchers all

  3. Home Economics Archive: Research, Tradition and History (HEARTH)

    Science.gov (United States)

    Click here to go to the Mann Library Home Page Click here to return to the HEARTH Home Page Click , Tradition and History HEARTH is a core electronic collection of books and journals in Home Economics and Archive: Research, Tradition and History (HEARTH). Ithaca, NY: Albert R. Mann Library, Cornell University

  4. A statistical approach to traditional Vietnamese medical diagnoses standardization

    International Nuclear Information System (INIS)

    Nguyen Hoang Phuong; Nguyen Quang Hoa; Le Dinh Long

    1990-12-01

    In this paper the first results of the statistical approach for Cold-Heat diagnosis standardization as a first work in the ''eight rules diagnoses'' standardization of Traditional Vietnamese Medicine are briefly described. Some conclusions and suggestions for further work are given. 3 refs, 2 tabs

  5. Blending Online Learning with Traditional Approaches: Changing Practices

    Science.gov (United States)

    Condie, Rae; Livingston, Kay

    2007-01-01

    Considerable claims have been made for the development of e-learning, either as stand-alone programmes or alongside more traditional approaches to teaching and learning, for students across school and tertiary education. National initiatives have improved the position of schools in terms of access to hardware and electronic networking, software…

  6. A Comparison of HPT and Traditional Training Approaches.

    Science.gov (United States)

    Kretz, Richard

    2002-01-01

    Focuses on the comparative use of training from human performance technology (HPT) and traditional training perspectives, based on taxonomy. Concludes that the primary difference is a holistic systems performance improvement approach by eliminating barriers with HPT versus reaction or response to a set of business objectives in traditional…

  7. Facilities upgrade for natural forces: traditional vs. realistic approach

    International Nuclear Information System (INIS)

    Terkun, V.

    1985-01-01

    The traditional method utilized for upgrading existing buildings and equipment involves the following steps: performs structural study using finite element analysis and some in situ testing; compare predicted member forces/stresses to material code allowables; determine strengthening schemes for those structural members judged to be weak; estimate cost for required upgrades. This approach will result in structural modifications that are not only conservative but very expensive as well. The realistic structural evaluation approach uses traditional data to predict structural weaknesses as a final step. Next, using considerable information now available for buildings and equipment exposed to natural hazards, engineering judgments about structures being evaluated can be made with a great deal of confidence. This approach does not eliminate conservatism entirely, but it does reduce it to a reasonable and realistic level. As a result, the upgrade cost goes down without compromising the low risk necessary for vital facilities

  8. Research Approaches in the Study of Religion

    Directory of Open Access Journals (Sweden)

    Szocik Konrad

    2015-02-01

    Full Text Available Despite development of secular ideas and concepts in the Western world, we can observe increasing interest in the study of religion. However, this popularity of the study of religion and different research approaches has caused that in some sense scholars that were studying religion came to a dead point. Here I show that the most optimal research approach in the study of religion is pluralistic, integral paradigm which connects old traditional methods with naturalistic, cognitive and sometimes experimental approach.

  9. The Traditional Centralized Model of Institutional Research: Its Derivation & Evolution at One College.

    Science.gov (United States)

    Slark, Julie

    A description is provided of Rancho Santiago College's institutional research program, which uses a traditional centralized research model, augmented with alternative, decentralized approaches. First, background information is presented on the college and the role of the research office in management, decision-making, and educational support.…

  10. A non-traditional multinational approach to construction inspection program

    International Nuclear Information System (INIS)

    Ram, Srinivasan; Smith, M.E.; Walker, T.F.

    2007-01-01

    The next generation of nuclear plants would be fabricated, constructed and licensed in markedly different ways than the present light water reactors. Non-traditional commercial nuclear industry suppliers, shipyards in Usa and international fabricators, would be a source to supply major components and subsystems. The codes of construction may vary depending upon the prevailing codes and standards used by the respective supplier. Such codes and standards need to be reconciled with the applicable regulations (e.g., 10 CFR 52). A Construction Inspection Program is an integral part of the Quality Assurance Measures required during the Construction Phase of the power plant. In order to achieve the stated cost and schedule goals of the new build plants, a nontraditional multi-national approach would be required. In lieu of the traditional approach of individual utility inspecting the quality of fabrication and construction, a multi-utility team approach is a method that will be discussed. Likewise, a multinational cooperative licensing approach is suggested taking advantage of inspectors of the regulatory authority where the component would be built. The multi-national approach proposed here is based on the principle of forming teaming agreements between the utilities, vendors and the regulators. For instance, rather than sending Country A's inspectors all over the world, inspectors of the regulator in Country B where a particular component is being fabricated would in fact be performing the required inspections for Country A's regulator. Similarly teaming arrangements could be set up between utilities and vendors in different countries. The required oversight for the utility or the vendor could be performed by their counterparts in the country where a particular item is being fabricated

  11. A Comparison of Student Academic Performance with Traditional, Online, and Flipped Instructional Approaches in a C# Programming Course

    Science.gov (United States)

    Sharp, Jason H.; Sharp, Laurie A.

    2017-01-01

    Aim/Purpose: Compared student academic performance on specific course requirements in a C# programming course across three instructional approaches: traditional, online, and flipped. Background: Addressed the following research question--When compared to the online and traditional instructional approaches, does the flipped instructional approach…

  12. [Application of Delphi method in traditional Chinese medicine clinical research].

    Science.gov (United States)

    Bi, Ying-fei; Mao, Jing-yuan

    2012-03-01

    In recent years, Delphi method has been widely applied in traditional Chinese medicine (TCM) clinical research. This article analyzed the present application situation of Delphi method in TCM clinical research, and discussed some problems presented in the choice of evaluation method, classification of observation indexes and selection of survey items. On the basis of present application of Delphi method, the author analyzed the method on questionnaire making, selection of experts, evaluation of observation indexes and selection of survey items. Furthermore, the author summarized the steps of application of Delphi method in TCM clinical research.

  13. Approach to Health Supporting System Using Traditional Chinese Medicine

    Science.gov (United States)

    Watsuji, Tadashi; Shinohara, Shoji; Arita, Seizaburo

    The primary prevention of disease related to the lifestyle is an essential theme in medical research. Preventing before it arises is the important concept in traditional Chinese medicine (TCM). Since TCM, which emphasizes individual physical condition in medical treatment, has recently attracted considerable attention globally, objective diagnostic methods in TCM have been investigated in this work. Firstly, the fuzzy theory was applied to develop a tongue diagnosis supporting system based on the tongue diagnosis in TCM. Secondly, the usefulness of TCM health questionnaire was examined to identify individual physical condition. Our results suggest that the TCM health questionnaire is useful in the construction of a health supporting system based on TCM.

  14. Traditions and Transitions in Quantitative Societal Culture Research in Organization Studies

    DEFF Research Database (Denmark)

    Peterson, Mark, F.; Søndergaard, Mikael

    2011-01-01

    Quantitative societal culture research (QSCR) in organization studies crystallizes a configuration of social science perspectives and methods that became prominent in the 1970s. We consider the qualities of and boundaries around cultural groups that this tradition emphasizes, and other...... characteristics of cultural groups that it does not emphasize. Current debates surrounding this tradition reflect both recent social science innovations and rediscoveries of early social science perspectives. Our analysis of quantitative cross-cultural societal research in organization studies considers...... this process of crystallization, innovation and rediscovery. We suggest ways to address current controversies and promote conversations with other research approaches....

  15. [Genomic research of traditional Chinese medicines in vivo metabolism].

    Science.gov (United States)

    Xiao, Shui-Ming; Bai, Rui; Zhang, Xiao-Yan

    2016-11-01

    Gene is the base of in vivo metabolism and effectiveness for traditional Chinese medicines (TCM), and the gene expression, regulation and modification are used as the research directions to perform the TCM multi-component, multi-link and multi-target in vivo metabolism studies, which will improve the research on TCM metabolic proecess, effect target and molecular mechanism. Humans are superorganisms with 1% genes inherited from parents and 99% genes from various parts of the human body, mainly coming from the microorganisms in intestinal flora. These indicate that genetically inherited human genome and "second genome" could affect the TCM in vivo metabolism from inheritance and "environmental" aspects respectively. In the present paper, typical case study was used to discuss related TCM in vivo metabolic genomics research, mainly including TCM genomics research and gut metagenomics research, as well as the personalized medicine evoked from the individual difference of above genomics (metagenomics). Copyright© by the Chinese Pharmaceutical Association.

  16. Antioxidant Capacity of Beetroot: Traditional vs Novel Approaches.

    Science.gov (United States)

    Carrillo, Celia; Rey, Raquel; Hendrickx, Marc; Del Mar Cavia, María; Alonso-Torre, Sara

    2017-09-01

    Red beetroot has been ranked among the 10 most potent antioxidant vegetables, although only extraction-based methods have been used to evaluate its total antioxidant capacity. Therefore, the present study aims at comparing the traditional extraction-based method with two more recent approaches (QUENCHER -QUick, Easy, New, CHEap and Reproducible- and GAR -global antioxidant response method), in order to establish their suitability in the case of beetroot. Our results indicate that the total antioxidant capacity of beetroot would be underestimated when using extraction-based procedures, since both QUENCHER and GAR methods resulted in a higher total antioxidant capacity. The effect of a thermal treatment on the total antioxidant capacity of beetroot varies among the methods evaluated and our findings suggest different compounds responsible for the total antioxidant capacity detected in each pre-processing method. Remarkably, the present study demonstrates that the traditional extraction-based method seems useful to screen for (changes in) the "bioavailable" antioxidant potential of the root.

  17. Comparison of Quantitative and Qualitative Research Traditions: Epistemological, Theoretical, and Methodological Differences

    Science.gov (United States)

    Yilmaz, Kaya

    2013-01-01

    There has been much discussion about quantitative and qualitative approaches to research in different disciplines. In the behavioural and social sciences, these two paradigms are compared to reveal their relative strengths and weaknesses. But the debate about both traditions has commonly taken place in academic books. It is hard to find an article…

  18. A Declarative Design Approach to Modeling Traditional and Non-Traditional Space Systems

    Science.gov (United States)

    Hoag, Lucy M.

    The space system design process is known to be laborious, complex, and computationally demanding. It is highly multi-disciplinary, involving several interdependent subsystems that must be both highly optimized and reliable due to the high cost of launch. Satellites must also be capable of operating in harsh and unpredictable environments, so integrating high-fidelity analysis is important. To address each of these concerns, a holistic design approach is necessary. However, while the sophistication of space systems has evolved significantly in the last 60 years, improvements in the design process have been comparatively stagnant. Space systems continue to be designed using a procedural, subsystem-by-subsystem approach. This method is inadequate since it generally requires extensive iteration and limited or heuristic-based search, which can be slow, labor-intensive, and inaccurate. The use of a declarative design approach can potentially address these inadequacies. In the declarative programming style, the focus of a problem is placed on what the objective is, and not necessarily how it should be achieved. In the context of design, this entails knowledge expressed as a declaration of statements that are true about the desired artifact instead of explicit instructions on how to implement it. A well-known technique is through constraint-based reasoning, where a design problem is represented as a network of rules and constraints that are reasoned across by a solver to dynamically discover the optimal candidate(s). This enables implicit instantiation of the tradespace and allows for automatic generation of all feasible design candidates. As such, this approach also appears to be well-suited to modeling adaptable space systems, which generally have large tradespaces and possess configurations that are not well-known a priori. This research applied a declarative design approach to holistic satellite design and to tradespace exploration for adaptable space systems. The

  19. Current application of chemometrics in traditional Chinese herbal medicine research.

    Science.gov (United States)

    Huang, Yipeng; Wu, Zhenwei; Su, Rihui; Ruan, Guihua; Du, Fuyou; Li, Gongke

    2016-07-15

    Traditional Chinese herbal medicines (TCHMs) are promising approach for the treatment of various diseases which have attracted increasing attention all over the world. Chemometrics in quality control of TCHMs are great useful tools that harnessing mathematics, statistics and other methods to acquire information maximally from the data obtained from various analytical approaches. This feature article focuses on the recent studies which evaluating the pharmacological efficacy and quality of TCHMs by determining, identifying and discriminating the bioactive or marker components in different samples with the help of chemometric techniques. In this work, the application of chemometric techniques in the classification of TCHMs based on their efficacy and usage was introduced. The recent advances of chemometrics applied in the chemical analysis of TCHMs were reviewed in detail. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Traditional Chinese medicine research and education in Canada.

    Science.gov (United States)

    Ghayur, Muhammad Nabeel

    2009-06-01

    Abstract Traditional Chinese Medicine (TCM) is one of the oldest forms of medicine in the world. There has been a growing interest in TCM in Canada in terms of consumers and also among the research community. To cater for this interest, the Canadian Institute of Chinese Medicinal Research (CICMR) was established in 2004. Since its formation, CICMR has been organizing annual meetings. In 2008, the CICMR meeting, jointly organized with the Ontario Ginseng Innovation Research Centre, was held from October 16th to 19th, in London, Ontario, Canada. The meeting saw a number of participants and speakers from many countries who discussed TCM in a Canadian perspective. The talks and presentations focused on TCM practices in Asia and Canada; analytical techniques for unravelling the science behind TCM; basic and clinical research findings in the areas of cancer and cardiovascular diseases; safety and quality control issues; the regulatory and educational framework of TCM in Canada; and the latest findings in agricultural, chemical, and pharmacological research on ginseng from all over the world. The meeting successfully provided a platform for constructive discussions on TCM practices and research and education in Canada and the world.

  1. Mineralogy: a modern approach to teaching a traditional discipline

    Science.gov (United States)

    Cook, G. W.

    2011-12-01

    Mineralogy has traditionally been a primary component in undergraduate geoscience curriculum. In recent years, there has been a trend in which mineralogy and petrology have been combined into Earth Materials courses. This is unfortunate as these disciplines each have much to offer students, and content once considered essential is eliminated out of necessity. Mineralogy is still fundamental to students' understanding of the Earth and Earth processes. Using a modern approach to time-honored concepts, I teach a quarter-long Introductory Mineralogy class offered through the Scripps Institution of Oceanography at the University of California, San Diego. Student evaluations of this course unequivocally indicate a high degree of learning and interest in the material, confirming that mineralogy continues to be a valuable class into the 21st century. While much of the content remains similar to what has been taught over the last century, my strategy involves a well-balanced approach to old and new. The first third of the course is background including the relevance of mineralogy, crystal chemistry, and crystallography; the second third of the course is systematic mineralogy using the Dana system; the last third of the course is devoted to understanding optical mineralogy, using modern analytical equipment such as XRD and SEM, and learning to use the petrographic microscope. Throughout the quarter, a strong emphasis is placed on the importance of hand-sample identification. Field work, traditionally not emphasized in mineralogy courses, has been re-introduced to the curriculum. I use modern technology to facilitate and support student learning. A lecture-based approach is employed with carefully crafted and organized PowerPoint presentations. PowerPoint lectures can be effective and highly engaging. The key is to ensure that the lectures are not overly reliant on text, instead relying on diagrams, charts, photos, and embedded media such as 3-D animations (ex. to teach

  2. Towards Multi-Method Research Approach in Empirical Software Engineering

    Science.gov (United States)

    Mandić, Vladimir; Markkula, Jouni; Oivo, Markku

    This paper presents results of a literature analysis on Empirical Research Approaches in Software Engineering (SE). The analysis explores reasons why traditional methods, such as statistical hypothesis testing and experiment replication are weakly utilized in the field of SE. It appears that basic assumptions and preconditions of the traditional methods are contradicting the actual situation in the SE. Furthermore, we have identified main issues that should be considered by the researcher when selecting the research approach. In virtue of reasons for weak utilization of traditional methods we propose stronger use of Multi-Method approach with Pragmatism as the philosophical standpoint.

  3. Target identification of natural and traditional medicines with quantitative chemical proteomics approaches.

    Science.gov (United States)

    Wang, Jigang; Gao, Liqian; Lee, Yew Mun; Kalesh, Karunakaran A; Ong, Yong Siang; Lim, Jaehong; Jee, Joo-Eun; Sun, Hongyan; Lee, Su Seong; Hua, Zi-Chun; Lin, Qingsong

    2016-06-01

    Natural and traditional medicines, being a great source of drugs and drug leads, have regained wide interests due to the limited success of high-throughput screening of compound libraries in the past few decades and the recent technology advancement. Many drugs/bioactive compounds exert their functions through interaction with their protein targets, with more and more drugs showing their ability to target multiple proteins, thus target identification has an important role in drug discovery and biomedical research fields. Identifying drug targets not only furthers the understanding of the mechanism of action (MOA) of a drug but also reveals its potential therapeutic applications and adverse side effects. Chemical proteomics makes use of affinity chromatography approaches coupled with mass spectrometry to systematically identify small molecule-protein interactions. Although traditional affinity-based chemical proteomics approaches have made great progress in the identification of cellular targets and elucidation of MOAs of many bioactive molecules, nonspecific binding remains a major issue which may reduce the accuracy of target identification and may hamper the drug development process. Recently, quantitative proteomics approaches, namely, metabolic labeling, chemical labeling, or label-free approaches, have been implemented in target identification to overcome such limitations. In this review, we will summarize and discuss the recent advances in the application of various quantitative chemical proteomics approaches for the identification of targets of natural and traditional medicines. Copyright © 2016. Published by Elsevier Inc.

  4. Research advances in traditional Chinese medicine syndromes in cancer patients.

    Science.gov (United States)

    Ji, Qing; Luo, Yun-quan; Wang, Wen-hai; Liu, Xuan; Li, Qi; Su, Shi-bing

    2016-01-01

    Traditional Chinese medicine (TCM) syndrome, also known as TCM ZHENG or TCM pattern, is an integral and essential part of TCM theory that helps to guide the design of individualized treatments. A TCM syndrome, in essence, is a characteristic profile of all clinical manifestations in one patient that can be readily identified by a TCM practitioner. In this article, the authors reviewed the presentations of TCM syndromes in seven common malignancies (liver, lung, gastric, breast, colorectal, pancreatic and esophageal cancers), the objectivity and the standardization of TCM syndrome differentiation, the evaluation of TCM syndrome modeling in cancer research, and syndrome differentiation-guided TCM treatment of cancers. A better understanding of TCM syndrome theory, as well as its potential biological basis, may contribute greatly to the clinical TCM diagnosis and the treatment of cancer.

  5. Clinical research of traditional Chinese medicine in big data era.

    Science.gov (United States)

    Zhang, Junhua; Zhang, Boli

    2014-09-01

    With the advent of big data era, our thinking, technology and methodology are being transformed. Data-intensive scientific discovery based on big data, named "The Fourth Paradigm," has become a new paradigm of scientific research. Along with the development and application of the Internet information technology in the field of healthcare, individual health records, clinical data of diagnosis and treatment, and genomic data have been accumulated dramatically, which generates big data in medical field for clinical research and assessment. With the support of big data, the defects and weakness may be overcome in the methodology of the conventional clinical evaluation based on sampling. Our research target shifts from the "causality inference" to "correlativity analysis." This not only facilitates the evaluation of individualized treatment, disease prediction, prevention and prognosis, but also is suitable for the practice of preventive healthcare and symptom pattern differentiation for treatment in terms of traditional Chinese medicine (TCM), and for the post-marketing evaluation of Chinese patent medicines. To conduct clinical studies involved in big data in TCM domain, top level design is needed and should be performed orderly. The fundamental construction and innovation studies should be strengthened in the sections of data platform creation, data analysis technology and big-data professionals fostering and training.

  6. Intellectual property rights, benefit-sharing and development of "improved traditional medicines": A new approach.

    Science.gov (United States)

    Willcox, Merlin; Diallo, Drissa; Sanogo, Rokia; Giani, Sergio; Graz, Bertrand; Falquet, Jacques; Bodeker, Gerard

    2015-12-24

    Protection of intellectual property rights and benefit-sharing are key issues for all ethnopharmacological research. The International Society of Ethnobiology has produced helpful guidelines on access and benefit-sharing which are widely viewed as a "gold standard" but the question remains how best to apply these guidelines in practice. Difficult questions include ownership of traditional knowledge, making appropriate agreements, and how appropriately to share benefits. We present the case study of the development of an "improved traditional medicine" for malaria in Mali and we report how benefit-sharing was applied in this case. The knowledge about the selected plant came independently from several families and traditional healers. The IPR approach was to recognise that this traditional knowledge belongs to the people of Mali and was used for their benefit in developing a new "improved traditional medicine" (ITM). The traditional healer whose method of preparation was used, and who collaborated in clinical trials, did not request any financial reward but asked for the ITM to be named after him. The most sustainable benefit for the community was sharing the results of which preparation of which medicinal plant seemed to be the most effective for treating malaria. Attempts at providing a health centre and training a health worker for the village did not prove to be sustainable. Respect for intellectual property rights and benefit-sharing are possible even in a context where the knowledge is not owned by a clearly identified person or group of people. The most sustainable benefits are intangible rather than material: namely recognition, improved knowledge about which traditional treatment is the best and how to prepare and take it. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  7. Reaching the Non-Traditional Stopout Population: A Segmentation Approach

    Science.gov (United States)

    Schatzel, Kim; Callahan, Thomas; Scott, Crystal J.; Davis, Timothy

    2011-01-01

    An estimated 21% of 25-34-year-olds in the United States, about eight million individuals, have attended college and quit before completing a degree. These non-traditional students may or may not return to college. Those who return to college are referred to as stopouts, whereas those who do not return are referred to as stayouts. In the face of…

  8. Functional dyspepsia: A new approach from traditional Persian medicine

    Directory of Open Access Journals (Sweden)

    Mehdi Pasalar

    2016-03-01

    Full Text Available Objective: One of the most common global disorders is related to gastrointestinal system. Functional dyspepsia (FD defined as upper abdominal pain and discomfort in the absence of organic ailments is a prevalent disease without any confirmed medication. The purpose of this study was to find gastric disorders which might be coincidental to FD based on traditional Persian medicine (TPM. Materials and Methods: We searched the main textbooks of TPM including Al-Havi (by Rhazes, Canon of medicine (by Avicenna, ZakhireKhawrazmshahi (by Ismail Jorjani, Moalijat-e Aghili and Makhzan Al-adviya (by Mohammad Hosein AghiliShirazi, and ExirAzam (by Hakim Azam Khan. Also, we searched Pubmed, Scopus, Science Direct, Medline, scientific information database (SID, Iranmedex and Google Scholar from 1980 to 1 August 2014 for dyspepsia, gastrointestinal disease, traditional Persian medicine, and gastric dystemperaments. Results: There is no equivalent term for FD in traditional Persian medicine although similar signs and symptoms are visible in terms like simple cold dystemperament of stomach, indigestion, and digestion debility in TPM sources. Some treatments mentioned in TPM have shown promising results in the current experimental tests. Conclusion: Finding these similarities in complementary and alternative medicine (CAM textbooks may lead to discovering new remedies for this widespread disease.

  9. Functional dyspepsia: A new approach from traditional Persian medicine

    Science.gov (United States)

    Pasalar, Mehdi; Nimrouzi, Majid; Choopani, Rasool; Mosaddegh, Mahmoud; Kamalinejad, Mohammad; Mohagheghzadeh, Abdolali; Bagheri Lankarani, Kamran

    2016-01-01

    Objective: One of the most common global disorders is related to gastrointestinal system. Functional dyspepsia (FD) defined as upper abdominal pain and discomfort in the absence of organic ailments is a prevalent disease without any confirmed medication. The purpose of this study was to find gastric disorders which might be coincidental to FD based on traditional Persian medicine (TPM). Materials and Methods: We searched the main textbooks of TPM including Al-Havi (by Rhazes), Canon of medicine (by Avicenna), ZakhireKhawrazmshahi (by Ismail Jorjani), Moalijat-e Aghili and Makhzan Al-adviya (by Mohammad Hosein AghiliShirazi), and ExirAzam (by Hakim Azam Khan). Also, we searched Pubmed, Scopus, Science Direct, Medline, scientific information database (SID), Iranmedex and Google Scholar from 1980 to 1 August 2014 for dyspepsia, gastrointestinal disease, traditional Persian medicine, and gastric dystemperaments. Results: There is no equivalent term for FD in traditional Persian medicine although similar signs and symptoms are visible in terms like simple cold dystemperament of stomach, indigestion, and digestion debility in TPM sources. Some treatments mentioned in TPM have shown promising results in the current experimental tests. Conclusion: Finding these similarities in complementary and alternative medicine (CAM) textbooks may lead to discovering new remedies for this widespread disease. PMID:27222829

  10. The Use of Omic Technologies Applied to Traditional Chinese Medicine Research

    Directory of Open Access Journals (Sweden)

    Dalinda Isabel Sánchez-Vidaña

    2017-01-01

    Full Text Available Natural products represent one of the most important reservoirs of structural and chemical diversity for the generation of leads in the drug development process. A growing number of researchers have shown interest in the development of drugs based on Chinese herbs. In this review, the use and potential of omic technologies as powerful tools in the modernization of traditional Chinese medicine are discussed. The analytical combination from each omic approach is crucial for understanding the working mechanisms of cells, tissues, organs, and organisms as well as the mechanisms of disease. Gradually, omic approaches have been introduced in every stage of the drug development process to generate high-quality Chinese medicine-based drugs. Finally, the future picture of the use of omic technologies is a promising tool and arena for further improvement in the modernization of traditional Chinese medicine.

  11. Research Capacity at Traditional Chinese Medicine (TCM) Centers in China: A Survey of Clinical Investigators.

    Science.gov (United States)

    Feng, Shuo; Han, Mei; Lai, Lily; Wang, Si-Cheng; Liu, Jian-Ping

    2017-01-01

    Background. The development of an evidence-based approach to traditional Chinese medicine (TCM), which depends on the generation of good quality evidence, requires an adequate workforce. However, the research capacity of TCM investigators is not known. Study Design. This cross-sectional study was conducted to describe the research capacity of TCM clinical investigators in China. Participants. A total of 584 participants from TCM hospitals and research centers were included. They were asked about the academic and research characteristics, needs for research capacity building, and barriers to clinical research. Results. The majority (80.82%) were qualified to at least a Master's degree, whilst a smaller proportion (40.24%) held a senior professional title. We found that academic outputs were low with the majority (62.16%) authoring less than five publications in total. The most pressing needs for building research capacity identified were training in research methodology (97.43%) and identification of research questions (86.81%), whilst the highest ranking barriers to conducting research were limited motivation, funding (40.72%), and time (37.15%). Conclusion. The methodology training, along with investment in the research workforce, needs to be urgently addressed to improve investigators' research capacity and the development of an evidence-based approach of TCM.

  12. Research Capacity at Traditional Chinese Medicine (TCM Centers in China: A Survey of Clinical Investigators

    Directory of Open Access Journals (Sweden)

    Shuo Feng

    2017-01-01

    Full Text Available Background. The development of an evidence-based approach to traditional Chinese medicine (TCM, which depends on the generation of good quality evidence, requires an adequate workforce. However, the research capacity of TCM investigators is not known. Study Design. This cross-sectional study was conducted to describe the research capacity of TCM clinical investigators in China. Participants. A total of 584 participants from TCM hospitals and research centers were included. They were asked about the academic and research characteristics, needs for research capacity building, and barriers to clinical research. Results. The majority (80.82% were qualified to at least a Master’s degree, whilst a smaller proportion (40.24% held a senior professional title. We found that academic outputs were low with the majority (62.16% authoring less than five publications in total. The most pressing needs for building research capacity identified were training in research methodology (97.43% and identification of research questions (86.81%, whilst the highest ranking barriers to conducting research were limited motivation, funding (40.72%, and time (37.15%. Conclusion. The methodology training, along with investment in the research workforce, needs to be urgently addressed to improve investigators’ research capacity and the development of an evidence-based approach of TCM.

  13. [Investigation, collation and research of traditional Dai medicine of China].

    Science.gov (United States)

    Zhang, Li-Xia; Zhang, Zhong-Lian; Li, Hai-Tao; Niu, Ying-Fen; Guan, Yan-Hong; Ma, Xiao-Jun

    2016-08-01

    In order to find out the composition, characteristics and traditional utilization characteristics of Dai medicine and promote the rational protection, inheritance and utilization of the resources and traditional knowledge of Dai medicine in China, the resources of traditional Dai medicine have been investigated systematically and the traditional knowledge of Dai medicine have been analyzed in the article. We found out that there were altogether 1 077 kinds of traditional Dai medicine in China and among which 272 were the first time recorded in the condition of Dai folk medical uses. There were 1 053 plant medicines which belong to 169 family and 694 genus. These plant medicines mainly distributed in the southern, west southern and east southern area of Yunnan province, the southern area of Guangxi, Guangdong, Guizhou, Sichuan, Fujian province and tropical, subtropical district as Taiwan, and more than 94.49% plant medicines could be found in Yunnan province. From the point of plant life form, they were major herbaceous or shrubby plants; When it is used as medicinal part, root and rhizome of plants account for the highest proportion, the next were whole plant and leaves. From nature, flavor and channel tropism points of view, the largest proportion of Dai medicines were cool, bitter-tasted and possesses water element. In terms of treatment of disease types, most of the drugs can treat gastrointestinal diseases, next were drugs that could be used to treat upper respiratory infection, traumatological and rheumatic diseases, urinary infection, gynecological diseases, hepatopathy, puerperium fever and diseases caused by poisonous insects and beast of prey bite. The study revealed that the resources of traditional Dai medicine and traditional knowledge of application were abundant in China, but the resources of traditional Dai medicine and traditional knowledge of application were faced with the risk of gradually reduce and loss. The article suggested that we should

  14. Comparison of a Traditional Probabilistic Risk Assessment Approach with Advanced Safety Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Curtis L; Mandelli, Diego; Zhegang Ma

    2014-11-01

    As part of the Light Water Sustainability Program (LWRS) [1], the purpose of the Risk Informed Safety Margin Characterization (RISMC) [2] Pathway research and development (R&D) is to support plant decisions for risk-informed margin management with the aim to improve economics, reliability, and sustain safety of current NPPs. In this paper, we describe the RISMC analysis process illustrating how mechanistic and probabilistic approaches are combined in order to estimate a safety margin. We use the scenario of a “station blackout” (SBO) wherein offsite power and onsite power is lost, thereby causing a challenge to plant safety systems. We describe the RISMC approach, illustrate the station blackout modeling, and contrast this with traditional risk analysis modeling for this type of accident scenario. We also describe our approach we are using to represent advanced flooding analysis.

  15. Traditional and non-traditional approaches to the prediction of natural disasters

    Science.gov (United States)

    Sapunov, Valentin; Glazyrina, Tatiana

    2016-04-01

    information in space and in time - from the past or the future, however, a diffuse form. The less significant by energy event is, the farther it is remote in time, the less accurate it becomes the transmitted information. Hence: 1. Create in addition to traditional monitoring system for monitoring the behavior of animals that can anticipate disasters natural and anthropogenic genesis based on the properties proscopy. 2. Carry out laboratory investigations of the physical properties of time based on the ideas Kozyrev and other Russian scientists. 3. Some known devices may be used to predict the existing, such as torsion balance. 4. To develop a theoretical framework of proscopy is actual field of both theoretical and applied science.

  16. An ergonomic approach for designing indian traditional vegetable cutter.

    Science.gov (United States)

    Dhara, Prakash C; De, Sujaya; Sengupta, Piyali; Maity, Payel; Pal, Amitava

    2015-01-01

    In India varieties of hand tools have been used to cut the vegetables. Traditional vegetable cutter is a commonly used hand tool which has been used for years in the kitchen. The tool may have some design related problems. The present study was undertaken to reduce those problems. The study objective was to evaluate a new design of traditional vegetable cutters for use in the Indian kitchen. One hundred and fifty Indian women who regularly used a vegetable cutter for cooking purposes participated in this study. The design of the vegetable cutter was modified based on the postural preference of the users and other anthropometric factors including the blade angle, length, breadth and width of the sitting area. The prevalence of musculoskeletal disorders was assessed by means of a questionnaire for subjects' feedback. New concepts of the design were proposed and a few prototypes were made and were tested by paired comparison using the EMG system. A large number of subjects (61%) used the vegetable cutter while sitting on the floor with folded knees and the prevalence of MSD in most of the body parts was comparatively lower in this posture than that in squatting posture. In the new design, a broad platform was suggested to provide a more comfortable sitting when a subject sits on it with folded knees. For the vegetable cutter, the blade angle was made at 120° with a broad folded wooden base as the final prototype of the cutter. The length, breadth, and thickness of the base were selected based on the results of the anthropometric measurements among the prototypes of the cutters. The selected vegetable cutter showed the least myoelectric activity among the prototypes during cutting vegetables. The modified vegetable cutter appeared to be ergonomically effective, less prone to muscular stress, and compatible for preferred posture of the users.

  17. Research on the Application of Traditional Embroidery Technology in Modern Jewelry Creation

    Directory of Open Access Journals (Sweden)

    Min Li

    2017-10-01

    Full Text Available Tradition and modernity are the eternal topics of art, especially in the age of information.Efficient mechanical production methods to improve the traditional jewelry production process, which achieved the demand for mass production of jewelry.However, with the development of society and the progress of science and technology,  many traditional arts and crafts are lost.From the traditional culture, this paper analyzes the work of embroidery jewelry by studying the traditional Chinese embroidery culture and technique, summarizes the traditional embroidery technology and modern jewelry design techniques combined approach to guide the creative practice.On the basis of studying the theoretical method of combining traditional embroidery technology with modern jewelry, this paper focuses on the application of traditional embroidery techniques in jewelry creation, inspire the potential of traditional craft, to provide reference for modern jewelry design rich Chinese characteristics and attract the attention of  Chinese jewelry industry and inherit the traditional arts.

  18. Updating the CS Curriculum: Traditional vs. Market-Driven Approaches

    Directory of Open Access Journals (Sweden)

    Nedzad Mehic

    1999-01-01

    Full Text Available The paper describes a method of updating a curriculum of a typical computer science department. The suggested approach promotes the role of a university as an academic environment, targeting excellence in teaching degree programs, as well as a qualified partner in partnership with businesses, especially with industry, in sharing knowledge and skills, supporting the concept of a quality process and quality products. Cooperation with industry firms, through real problem solving approaches and using emerging technologies that might drive the best demand in future markets, will prepare students to take advantage of opportunities, gain experience, and make an impact immediately. As a case study, the paper describes how this approach is applied to Computer Science Department at University of Bahrain.

  19. Socio-cultural Tradition: From Theory to Research | Magut | Journal ...

    African Journals Online (AJOL)

    There are many theories that try to understand the broad nature of communication and how it applies to the individual or society but because of the complex nature of the topic, traditions are formed to help organize and explain different viewpoints and concepts. Robert Craig developed a model that labelled and separated ...

  20. A Comparison of Student Academic Performance with Traditional, Online, And Flipped Instructional Approaches in a C# Programming Course

    Directory of Open Access Journals (Sweden)

    Jason H. Sharp

    2017-08-01

    Full Text Available Aim/Purpose: Compared student academic performance on specific course requirements in a C# programming course across three instructional approaches: traditional, online, and flipped. Background: Addressed the following research question: When compared to the online and traditional instructional approaches, does the flipped instructional approach have a greater impact on student academic performance with specific course requirements in a C# programming course? Methodology: Quantitative research design conducted over eight 16-week semesters among a total of 271 participants who were undergraduate students en-rolled in a C# programming course. Data collected were grades earned from specific course requirements and were analyzed with the nonparametric Kruskal Wallis H-Test using IBM SPSS Statistics, Version 23. Contribution: Provides empirical findings related to the impact that different instructional approaches have on student academic performance in a C# programming course. Also describes implications and recommendations for instructors of programming courses regarding instructional approaches that facilitate active learning, student engagement, and self-regulation. Findings: Resulted in four statistically significant findings, indicating that the online and flipped instructional approaches had a greater impact on student academic performance than the traditional approach. Recommendations for Practitioners: Implement instructional approaches such as online, flipped, or blended which foster active learning, student engagement, and self-regulation to increase student academic performance. Recommendation for Researchers: Build upon this study and others similar to it to include factors such as gender, age, ethnicity, and previous academic history. Impact on Society: Acknowledge the growing influence of technology on society as a whole. Higher education coursework and programs are evolving to encompass more digitally-based learning contexts, thus

  1. Negative pressure dressing combined with a traditional approach for ...

    African Journals Online (AJOL)

    2011-07-21

    Jul 21, 2011 ... Deep burns of the calvarium due to high-voltage electrical current present serious therapeutic challenges in the healing. In this study, as an alternative approach to the treatment of burned skull, negative pressure dressing is used to facilitate separation of the necrotic bones from healthy margins of the ...

  2. A Modern Clinical Approach of the Traditional Korean Saam Acupuncture

    Directory of Open Access Journals (Sweden)

    Manyong Park

    2015-01-01

    Full Text Available Saam acupuncture is one of the original therapeutic modalities representing traditional Korean medicine. It was originally described in a manuscript that is estimated to be published at some point between 1644 and 1742, in the middle of the Cho Sun dynasty, by a Korean Buddhist monk whose name is unknown. The principle of combining five shu points is based on the theory of Nan-jing. The treatment and diagnosis concepts in Saam acupuncture were mainly influenced by Dongeuibogam and Chimgoogyeong-heombang. The basic characteristic of combining five shu points in Saam acupuncture is the selection of the tonification and sedation points along the self-meridian and other meridians based on creation and governor relationships. Saam acupuncture clinical studies have mainly focused on musculoskeletal pain and autonomic nervous system regulation. From a neurophysiological perspective, Saam acupuncture, which involves five shu points as the main treatment aspect, has the advantage of increasing parasympathetic nerve activation and adjusting the balance of the autonomic nervous system. Inserting a needle into the skin layer while considering the respiratory phase and stimulating the needle gently and lightly could maximize the effect of Saam acupuncture. The specific Saam acupuncture prescribed should be identified on the basis of the neurobiological perspective.

  3. Holistic approach to functional constipation: Perspective of traditional Persian medicine.

    Science.gov (United States)

    Nimrouzi, Majid; Zarshenas, Mohammad M

    2015-11-23

    Traditional Persian medicine (TPM) proposes a different viewpoint to the chronic diseases. Diagnosis and implemented treatment are based on individual differences among patients. Constipation or Ea'teghal-e-batn is a condition in which the patient develops difficult or painful defecation. Based on TPM concepts, the fifirst digestion step starts from halq (oral cavity), and ends via defecation from the maq'ad (anus). Avicenna believed that four faculties, ha'zemeh (digestive), ja'zebeh (absorptive), ma'sekeh (retentive) and da'fe'eh (propulsive), are involved in the process of digestion and absorption of the ingested food and expelling the waste materials. The bowel movement and appearance of the stool is a measure for evaluating the gastrointestinal healthy function. Defecation should be with no pain and fecal material should have no burning and acuity. Low food intake or foods with dry temperament, dryness of gastrointestinal tract, diaphoresis and heavy exercise as well as intestine sensory loss were discussed as main causes of constipation. Management of constipation in TPM includes dietary schemes, oil massages and subsequently simple herbal medicines. According to TPM theories, the fifirst step in treating a disease is the elimination of disease causes (asbabe- maraz) and also providing the causes of health (asbab-e-sehhat). Health care providers should know the proper condition which the herbal medicines should be administered in and be able to guide the patients about the benefifits and hazards of herbal remedies, commonly used in their living origin.

  4. Mineralogical characterization of beach sand minerals: traditional and modern approaches

    International Nuclear Information System (INIS)

    Krishnamurthy, P.

    2016-01-01

    Precise identification of beach sand minerals is an essential prerequisite for the reserve estimation of a given deposit and also in the subsequent evaluation of the process flow sheet for its optimal recovery. Traditional methods that are used for the identification of the beach sand minerals such as magnetite, hematite, ilmenite, rutile, anatase, zircon, garnet, sillimanite, monazite, quartz and others include heavy liquid separation (bromoform and methylene iodide) and studying the optical properties of the grains from different fractions so as to identify the specific phases in a sample. Grain counting of specific minerals from a given sievefraction under a petrological microscope to estimate the mode and their subsequent conversion in to weight percent fractions forms the critical second stage that is followed by the reserve estimates. These methodologies are tedious and time consuming often involving a few days for a single sample. The paper introduces the numerous instrumental methods (XRF, XRD - Rietveld and CCSEM) of mineral speciation and their qualification in with case studies from the west coast deposits in India

  5. Research on Influence of Cloud Environment on Traditional Network Security

    Science.gov (United States)

    Ming, Xiaobo; Guo, Jinhua

    2018-02-01

    Cloud computing is a symbol of the progress of modern information network, cloud computing provides a lot of convenience to the Internet users, but it also brings a lot of risk to the Internet users. Second, one of the main reasons for Internet users to choose cloud computing is that the network security performance is great, it also is the cornerstone of cloud computing applications. This paper briefly explores the impact on cloud environment on traditional cybersecurity, and puts forward corresponding solutions.

  6. Non-traditional approaches to teaching GPS online

    Science.gov (United States)

    Matias, A.; Wolf, D. F., II

    2009-12-01

    Students are increasingly turning to the web for quality education that fits into their lives. Nonetheless, online learning brings challenges as well as a fresh opportunity for exploring pedagogical practices not present on traditional higher education programs, particularly in the sciences. A team of two dozen Empire State College-State University of New York instructional designers, faculty, and other staff are working on making science relevant to non-majors who may initially have anxiety about general education science courses. One of these courses, GPS and the New Geography, focuses on how Global Positioning System (GPS) technology provides a base for inquiry and scientific discovery from a range of environmental issues with local, regional, and global scope. GPS and the New Geography is an introductory level course developed under a grant supported by the Charitable Leadership Foundation. Taking advantage of the proliferation of tools currently available for online learning management systems, we explore current trends in Web 2.0 applications to aggregate and leverage data to create a nontraditional, interactive learning environment. Using our best practices to promote on-line discussion and interaction, these tools help engage students and foster deep learning. During the 15-week term students learn through case studies, problem-based exercises, and the use of scientific data; thus, expanding their spatial literacy and gain experience using real spatial technology tools to enhance their understanding of real-world issues. In particular, we present how the use of Mapblogs an in-house developed blogging platform that uses GIS interplaying with GPS units, interactive data presentations, intuitive visual working environments, harnessing RSS feeds, and other nontraditional Web 2.0 technology has successfully promoted active learning in the virtual learning environment.

  7. Research Note: Yavirau: A traditional Fijian fish drive as an example of culturally embedded community development

    Directory of Open Access Journals (Sweden)

    Fink, Michael

    2012-09-01

    Full Text Available A yavirau (traditional Fijian fish drive is an ancient Fijian custom which has been adapted to today’s needs. Implemented and organised by a village community without external assistance, this highly this culturally specific custom is an example of development on a local level. According to theorists and practitioners working on development issues, such a strategy for Community Development (CD is promising because it seizes current approaches as it fosters local, decentralised, cultural specific development and aims at a high level of local participation. This research note analyses a yavirau as an example of CD, showing its advantages as well as its limitations.

  8. Current dichotomy between traditional molecular biological and omic research in cancer biology and pharmacology.

    Science.gov (United States)

    Reinhold, William C

    2015-12-10

    There is currently a split within the cancer research community between traditional molecular biological hypothesis-driven and the more recent "omic" forms or research. While the molecular biological approach employs the tried and true single alteration-single response formulations of experimentation, the omic employs broad-based assay or sample collection approaches that generate large volumes of data. How to integrate the benefits of these two approaches in an efficient and productive fashion remains an outstanding issue. Ideally, one would merge the understandability, exactness, simplicity, and testability of the molecular biological approach, with the larger amounts of data, simultaneous consideration of multiple alterations, consideration of genes both of known interest along with the novel, cross-sample comparisons among cell lines and patient samples, and consideration of directed questions while simultaneously gaining exposure to the novel provided by the omic approach. While at the current time integration of the two disciplines remains problematic, attempts to do so are ongoing, and will be necessary for the understanding of the large cell line screens including the Developmental Therapeutics Program's NCI-60, the Broad Institute's Cancer Cell Line Encyclopedia, and the Wellcome Trust Sanger Institute's Cancer Genome Project, as well as the the Cancer Genome Atlas clinical samples project. Going forward there is significant benefit to be had from the integration of the molecular biological and the omic forms or research, with the desired goal being improved translational understanding and application.

  9. Reflections on Conventional and Traditional Methodology in Transnational Community Research

    DEFF Research Database (Denmark)

    Farah, Abdulkadir Osman

    2017-01-01

    Cultivating Pathways of Creative Research: New Horizons of Transformative Practice and Collaborative Imagination strives to cultivate new pathways of research and engagement in social sciences and humanities where cultivation is linked to cross-fertilization of creative theorizing...... pathways of creative research. They help us go beyond formalism of method and cultivate new pathways of research in social sciences and humanities, especially in sociology, anthropology, education, art and literature. The volume, second in the trilogy of Creative Research, which follows Pathways...... of Creative Research: Towards a Festival of Dialogues and is followed by Research as Realization: Science, Spirituality and Harmony is not only a pioneering contribution to the world research but also to rethinking and regenerating self, culture, society and the human condition....

  10. Business Process Management – A Traditional Approach Versus a Knowledge Based Approach

    Directory of Open Access Journals (Sweden)

    Roberto Paiano

    2015-12-01

    Full Text Available The enterprise management represents a heterogeneous aggregate of both resources and assets that need to be coordinated and orchestrated in order to reach the goals related to the business mission. Influences and forces that may influence this process, and also for that they should be considered, are not concentrated in the business environment, but they are related to the entireoperational context of a company. For this reason, business processes must be the most versatile and flexible with respect to the changes that occur within the whole operational context of a company.Considering the supportive role that information systems play in favour of Business Process Management - BPM, it is also essential to implement a constant, continuous and quick mechanism for the information system alignment with respect to the evolution followed by business processes.In particular, such mechanism must intervene on BPM systems in order to keep them aligned and compliant with respect to both the context changes and the regulations. In order to facilitate this alignment mechanism, companies are already referring to the support offered by specific solutions, such as knowledge bases. In this context, a possible solution might be the approach we propose, which is based on a specific framework called Process Management System. Our methodology implements a knowledge base support for business experts, which is not limited to the BPM operating phases, but includes also the engineering and prototyping activities of the corresponding information system. This paper aims to compare and evaluate a traditional BPM approach with respect to theapproach we propose. In effect, such analysis aims to emphasize the lack of traditional methodology especially with respect to the alignment between business processes and information systems, along with their compliance with context domain and regulations.

  11. Researches on Transcriptome Sequencing in the Study of Traditional Chinese Medicine

    Science.gov (United States)

    Xin, Jie; Zhang, Rong-chao; Wang, Lei

    2017-01-01

    Due to its incomparable advantages, the application of transcriptome sequencing in the study of traditional Chinese medicine attracts more and more attention of researchers, which greatly promote the development of traditional Chinese medicine. In this paper, the applications of transcriptome sequencing in traditional Chinese medicine were summarized by reviewing recent related papers. PMID:28900463

  12. Parental Involvement in the Musical Education of Violin Students: Suzuki and "Traditional" Approaches Compared

    Science.gov (United States)

    Bugeja, Clare

    2009-01-01

    This article investigates parental involvement in the musical education of violin students and the changing role of the parents' across the learning process. Two contexts were compared, one emphasising the Suzuki methodology and the other a "traditional" approach. Students learning "traditionally" are typically taught note reading from the…

  13. Research on Lahu’s traditional sports culture from the perspective of cultural ecology

    OpenAIRE

    Wang Youfeng

    2016-01-01

    This paper mainly researches Lahu’s traditional sports culture from the perspective of cultural ecology and analyzes the characteristics of Lahu’s traditional sports culture, and analyzes the characteristics of Lahu’s traditional sports culture from three aspects: natural ecological environment, social ecological environment and spiritual ecology. What’ more, Lahu’ traditional sports culture is not only a concrete expression of Lahu’s production form and life style or a symbol of Lahu’s relig...

  14. COMPARISON OF THE TRADITIONAL STRENGTH OF MATERIALS APPROACH TO DESIGN WITH THE FRACTURE MECHANICS APPROACH

    International Nuclear Information System (INIS)

    Z. Ceylan

    2002-01-01

    The objective of this activity is to show that the use of the traditional strength of materials approach to the drip shield and the waste package (WP) designs is bounding and appropriate when compared to the fracture mechanics approach. The scope of this activity is limited to determining the failure assessment diagrams for the two materials at issue: Ti-7 and Alloy 22. This calculation is intended for use in support of the license application design of the drip shield and the WP. This activity is associated with the drip shield and the WP designs. The activity evaluation for work package number P32 12234F2, included in ''Technical Work Plan for: Waste Package Design Description for LA'' (Ref. 1, p. A-6), has determined that the development of this document is subject to ''Quality Assurance Requirements and Description'' requirements. The control of the electronic management of data is accomplished in accordance with the methods specified in Reference 1, Section 10. AP-3.124, ''Design Calculations and Analysis'' (Ref. 2), is used to develop and document the calculation

  15. Internet research: improving traditional community analysis before launching a practice.

    Science.gov (United States)

    Barresi, B; Scott, C

    2000-01-01

    Optometric practice management experts have always recommended that optometrists thoroughly research the communities in which they are considering practicing. Until the Internet came along, demographic research was possible but often daunting. Today, say these authors, it's becoming quite a bit easier ... and they show us how.

  16. The Costs and Risks of Maturing Technologies, Traditionally vs. Evolutionary Approaches

    National Research Council Canada - National Science Library

    Pennock, Michael J; Rouse, William B

    2008-01-01

    .... This results in more frequent, smaller increments of deployed capability. In theory, evolutionary acquisition could be more cost effective than traditional acquisition approaches because it avoids most of the risk inherent...

  17. Bobath and traditional approaches in post-stroke gait rehabilitation in adults

    Directory of Open Access Journals (Sweden)

    Mikołajewska Emilia

    2017-02-01

    Full Text Available Study aim: The aim of this study was to compare the outcomes of a study of post-stroke gait reeducation using the Bobath neuro‑developmental treatment (NDT-Bobath method and the traditional approach.

  18. Bobath and traditional approaches in post-stroke gait rehabilitation in adults

    OpenAIRE

    Mikołajewska Emilia

    2017-01-01

    Study aim: The aim of this study was to compare the outcomes of a study of post-stroke gait reeducation using the Bobath neuro‑developmental treatment (NDT-Bobath) method and the traditional approach.

  19. General principles of researching the lexicon of traditional material culture

    Directory of Open Access Journals (Sweden)

    Nedeljkov Ljiljana

    2009-01-01

    Full Text Available The paper discusses a linguistic research of terminological systems connected with basic fields of human life and work which, in modern conditions, are either transformed into contemporary modern forms or gradually disappear due to changes in the way of life and work. The lexicon of material culture of native inhabitants of Vojvodina is examined, resulting in monographs on the terminologies of fishing, cartwrighting, shepherding and houses and furniture, all of which have in common the fact that the starting point was the research of the lexicon in question by semantic fields. The paper shows the lexicological and lexicographical procedures used while researching these terminological systems.

  20. Organizational Effectiveness = Corporate Performance? Why and How Two Research Traditions Need to be Merged

    NARCIS (Netherlands)

    Glunk, U.; Wilderom, C.P.M.

    1996-01-01

    Organizational effectiveness and corporate performance research seem to deal with the same core construct: organizational effectiveness/performance.However, both research traditions have produced separate bodies of literature and have developed different strengths and weaknesses.Organizational

  1. The effect of three different educational approaches on children's drawing ability: Steiner, Montessori and traditional.

    Science.gov (United States)

    Cox, M V; Rowlands, A

    2000-12-01

    Although there is a national curriculum for art education in the UK there are also alternative approaches in the private sector. This paper addresses the issue of the effect of these approaches on children's drawing ability. To compare the drawing ability in three drawing tasks of children in Steiner, Montessori and traditional schools. The participants were 60 school children between the ages of 5;11 and 7;2. Twenty children were tested in each type of school. Each child completed three drawings: a free drawing, a scene and an observational drawing. As predicted, the free and scene drawings of children in the Steiner school were rated more highly than those of children in Montessori and traditional schools. Steiner children's use of colour was also rated more highly, although they did not use more colours than the other children. Steiner children used significantly more fantasy topics in their free drawings. Further observation indicated that the Steiner children were better at using the whole page and organising their drawings into a scene; their drawings were also more detailed. Contrary to previous research Montessori children did not draw more inanimate objects and geometrical shapes or fewer people than other children. Also, contrary to the prediction, Steiner children were significantly better rather than worse than other children at observational drawing. The results suggest that the approach to art education in Steiner schools is conducive not only to more highly rated imaginative drawings in terms of general drawing ability and use of colour but also to more accurate and detailed observational drawings.

  2. Beyond traditional advertisements: leveraging Facebook's social structures for research recruitment.

    Science.gov (United States)

    Valdez, Rupa S; Guterbock, Thomas M; Thompson, Morgan J; Reilly, Jeremiah D; Menefee, Hannah K; Bennici, Maria S; Williams, Ishan C; Rexrode, Deborah L

    2014-10-27

    Obtaining access to a demographically and geographically diverse sample for health-related research can be costly and time consuming. Previous studies have reported mixed results regarding the potential of using social media-based advertisements to overcome these challenges. Our aim was to develop and assess the feasibility, benefits, and challenges of recruiting for research studies related to consumer health information technology (IT) by leveraging the social structures embedded in the social networking platform, Facebook. Two recruitment strategies that involved direct communication with existing Facebook groups and pages were developed and implemented in two distinct populations. The first recruitment strategy involved posting a survey link directly to consenting groups and pages and was used to recruit Filipino-Americans to a study assessing the perceptions, use of, and preferences for consumer health IT. This study took place between August and December 2013. The second recruitment strategy targeted individuals with type 2 diabetes and involved creating a study-related Facebook group and asking administrators of other groups and pages to publicize our group to their members. Group members were then directly invited to participate in an online pre-study survey. This portion of a larger study to understand existing health management practices as a foundation for consumer health IT design took place between May and June 2014. In executing both recruitment strategies, efforts were made to establish trust and transparency. Recruitment rate, cost, content of interaction, and characteristics of the sample obtained were used to assess the recruitment methods. The two recruitment methods yielded 87 and 79 complete responses, respectively. The first recruitment method yielded a rate of study completion proportionate to that of the rate of posts made, whereas recruitment successes of the second recruitment method seemed to follow directly from the actions of a subset

  3. Online marketing and advertising research: Traditional Theories Revisited

    OpenAIRE

    Yudhistira, Titah

    2016-01-01

    Online marketing and advertising instruments—and the ways in which consumers react to them—are always evolving, which results in ongoing gaps in knowledge. This dissertation aims to fill some of these gaps by providing a greater understanding of how the Internet impacts online marketing and advertising research. The first study in this dissertation describes how banner exposure characteristics, such as the number of exposures, spacing, and delay, impact consumer memory. The findings of this s...

  4. Transformative Learning: The Role of Research in Traditional Clinical Disciplines

    Science.gov (United States)

    Tims, Michael

    2014-01-01

    One of an educator’s main tasks is to develop the intellectual openness of students that is necessary for transformative learning to take place. An initial step in removing the constraint of assumption is to employ the process of unlearning in the classroom. Unlearning in its simplest form can be described as the process through which the student learns to ask questions about a subject on which they are passionate, and through critical reflection, to construct and validate a new understanding based on observations and information generated by the original questions. Developing the ability to improvise and innovate are clear and positive indications that unlearning has occurred, and the Maryland University of Integrative Health’s (MUIH’s) educators have found that integrating research methods into class and group projects can accelerate the unlearning process. MUIH promotes students’ effort to solve interesting problems using the community found within the classroom. The natural state of relativism found in group processes lends itself to making explicit the assumptions each individual brings to the process. MUIH’s methods include engaging students in visual deconstruction of research data found in graphs, tables, and images; having students identify the end point of a line of inquiry; and evaluating a previously accumulated body of evidence to determine if it supports a product’s claims (eg, claims about general health, structure-function, or therapeutic value). The ultimate aim in asking students to take part in research embedded in coursework is to provide an assessment of their abilities that is more closely linked to discipline-specific experience. MUIH’s method of ingraining a culture of inquiry into both classroom and independent research serves to enhance students’ self-awareness about the constraints of their own a priori thinking and to nurture a deeper trust in their own informed intuition. PMID:26770105

  5. [Research progress on potential liver toxic components in traditional Chinese medicine].

    Science.gov (United States)

    Wu, Hao; Zhong, Rong-Ling; Xia, Zhi; Huang, Hou-Cai; Zhong, Qing-Xiang; Feng, Liang; Song, Jie; Jia, Xiao-Bin

    2016-09-01

    In recent years, the proportion of traditional Chinese medicine in scientific research and its clinical use increased gradually. The research result also becomes more and more valuable, but in the process of using traditional Chinese medicine, it also needs to pay more attention. With the gradual deepening of the toxicity of traditional Chinese medicine, some traditional Chinese medicines have also been found to have the potential toxicity, with the exception of some traditional toxicity Chinese medicine. Traditional Chinese medicine in the growth, processing, processing, transportation and other aspects of pollution or deterioration will also cause the side effects to the body. Clinical practice should be based on the theory of traditional Chinese medicine to guide rational drug use and follow the symptomatic medication, the principle of proper compatibility. The constitution of the patients are different, except for a few varieties of traditional Chinese medicines are natural herbs with hepatotoxicity, liver toxicity of most of the traditional Chinese medicine has idiosyncratic features. The liver plays an important role in drug metabolism. It is easy to be damaged by drugs. Therefore, the study of traditional Chinese medicine potential liver toxicity and its toxic components has become one of the basic areas of traditional Chinese medicine research. Based on the review of the literatures, this paper summarizes the clinical classification of liver toxicity, the pathogenesis of target cell injury, and systematically summarizes the mechanism of liver toxicity and toxic mechanism of traditional Chinese medicine. This paper provided ideas for the study of potential liver toxicity of traditional Chinese medicine and protection for clinical safety of traditional Chinese medicine. Copyright© by the Chinese Pharmaceutical Association.

  6. Genetic programming based models in plant tissue culture: An addendum to traditional statistical approach.

    Science.gov (United States)

    Mridula, Meenu R; Nair, Ashalatha S; Kumar, K Satheesh

    2018-02-01

    In this paper, we compared the efficacy of observation based modeling approach using a genetic algorithm with the regular statistical analysis as an alternative methodology in plant research. Preliminary experimental data on in vitro rooting was taken for this study with an aim to understand the effect of charcoal and naphthalene acetic acid (NAA) on successful rooting and also to optimize the two variables for maximum result. Observation-based modelling, as well as traditional approach, could identify NAA as a critical factor in rooting of the plantlets under the experimental conditions employed. Symbolic regression analysis using the software deployed here optimised the treatments studied and was successful in identifying the complex non-linear interaction among the variables, with minimalistic preliminary data. The presence of charcoal in the culture medium has a significant impact on root generation by reducing basal callus mass formation. Such an approach is advantageous for establishing in vitro culture protocols as these models will have significant potential for saving time and expenditure in plant tissue culture laboratories, and it further reduces the need for specialised background.

  7. Comparison of traditional and recent approaches in the promotion of balance and strength in older adults.

    Science.gov (United States)

    Granacher, Urs; Muehlbauer, Thomas; Zahner, Lukas; Gollhofer, Albert; Kressig, Reto W

    2011-05-01

    Demographic change in industrialized countries produced an increase in the proportion of elderly people in our society, resulting in specific healthcare challenges. One such challenge is how to effectively deal with the increased risk of sustaining a fall and fall-related injuries in old age. Deficits in postural control and muscle strength represent important intrinsic fall risk factors. Thus, adequate training regimens need to be designed and applied that have the potential to reduce the rate of falling in older adults by countering these factors. Therefore, the purpose of this review is to compare traditional and recent approaches in the promotion of balance and strength in older adults. Traditionally, balance and resistance training programmes proved to be effective in improving balance and strength, and in reducing the number of falls. Yet, it was argued that these training protocols are not specific enough to induce adaptations in neuromuscular capacities that are specifically needed in actual balance-threatening situations (e.g. abilities to recover balance and to produce force explosively). Recent studies indicated that perturbation-based or multitask balance training and power/high-velocity resistance training have the potential to improve these specific capacities because they comply with the principle of training specificity. In fact, there is evidence that these specifically tailored training programmes are more effective in improving balance recovery mechanisms and muscle power than traditional training protocols. A few pilot studies have even shown that these recently designed training protocols have an impact on the reduction of fall incidence rate in older adults. Further research is needed to confirm these results and to elucidate the underlying mechanisms responsible for the adaptive processes.

  8. Practical Skills Training in Agricultural Education--A Comparison between Traditional and Blended Approaches

    Science.gov (United States)

    Deegan, Donna; Wims, Padraig; Pettit, Tony

    2016-01-01

    Purpose: In this article the use of blended learning multimedia materials as an education tool was compared with the traditional approach for skills training. Design/Methodology/Approach: This study was conducted in Ireland using a pre-test, post-test experimental design. All students were instructed on how to complete two skills using either a…

  9. A Holistic Approach to Evaluating Research

    International Development Research Centre (IDRC) Digital Library (Canada)

    production are demonstrating that the traditional view that science ... the two are entangled. .... Produces multi-, inter- or transdisciplinary research, sometimes across disparate fields. ..... provocative, color coding (“traffic lights”) may serve as a.

  10. [Research progress in phytoestrogens of traditional Chinese medicine].

    Science.gov (United States)

    Zhao, Yuan; Zheng, Hong-Xia; Xu, Ying; Lin, Na

    2017-09-01

    Phytoestrogens are plant-derived compounds, which have a similarity in structure with human endogenous estrogen 17-β-estradiol. Structural likeness enables phytoestrogens to interact with estrogen receptors, not simply mimicking the effects of human steroidal estrogen but also exhibiting similar and divergent actions. The global literature relating to phytoestrogen in recent years was systematically summarized in this paper. Chemical compositions of phytoestrogens were mainly flavonoids, coumarins, lignans, terpenoids, steroids, etc., with a character of prevention and treatment of perimenopausal syndrome, osteoporosis, cardiovascular disease, metabolic diseases, cancer, regulation of brain function and other pharmacological effects. The mechanisms of action mainly included classical estrogen receptor pathway, epigenetic effect, activation of 5'-adenosyl-phospho-activated protein kinase, inhibition of kinase, activation of peroxisome proliferator-activated receptor, regulation of apoptosis-related proteins, inhibition of nuclear factor κB signaling pathway and so on. According to their efficacy classification, phytoestrogens were mainly distributed in the tonifying medicines, blood-activating and stasis-resolving medicines and heat-clearing medicines. The classical prescriptions with estrogen activity included tonifying formula, Qi-regulating formula and harmonizing formula, etc. This review was aimed at providing a certain reference for the further study of phytoestrogens by researchers and clinicians. Copyright© by the Chinese Pharmaceutical Association.

  11. Research Notes ~ Selecting Research Areas and Research Design Approaches in Distance Education: Process Issues

    Directory of Open Access Journals (Sweden)

    Sudarshan Mishra

    2004-11-01

    Full Text Available The purpose of this paper is to study the process used for selecting research areas and methodological approaches in distance education in India. Experts from the field of distance education in India were interviewed at length, with the aim of collecting qualitative data on opinions on process-issues for selecting areas for research, research design, and appropriate methodological approaches in distance education. Data collected from these interviews were subjected to content analysis; triangulation and peer consultation techniques were used for cross-checking and data verification. While the findings and recommendations of this study have limited application in that they can only be used in the specific context outlined in this paper, respondents in this study nonetheless revealed the pressing need for more process-oriented research in examining media and technology, learners and learning, and distance learning evaluation processes. Our research, which yielded interesting empirical findings, also determined that a mixed approach – one that involves both quantitative and qualitative methods – is more appropriate for conducting research in distance education in India. Qualitative evidence from our research also indicates that respondents interviewed felt that emphasis should be placed on interdisciplinary and systemic research, over that of traditional disciplinary research. Research methods such as student self-reporting, extensive and highly targeted interviews, conversation and discourse analysis, were determined to as useful for data collection for this study.

  12. Functional vs. Traditional Analysis in Biomechanical Gait Data: An Alternative Statistical Approach.

    Science.gov (United States)

    Park, Jihong; Seeley, Matthew K; Francom, Devin; Reese, C Shane; Hopkins, J Ty

    2017-12-01

    In human motion studies, discrete points such as peak or average kinematic values are commonly selected to test hypotheses. The purpose of this study was to describe a functional data analysis and describe the advantages of using functional data analyses when compared with a traditional analysis of variance (ANOVA) approach. Nineteen healthy participants (age: 22 ± 2 yrs, body height: 1.7 ± 0.1 m, body mass: 73 ± 16 kg) walked under two different conditions: control and pain+effusion. Pain+effusion was induced by injection of sterile saline into the joint capsule and hypertonic saline into the infrapatellar fat pad. Sagittal-plane ankle, knee, and hip joint kinematics were recorded and compared following injections using 2×2 mixed model ANOVAs and FANOVAs. The results of ANOVAs detected a condition × time interaction for the peak ankle (F1,18 = 8.56, p = 0.01) and hip joint angle (F1,18 = 5.77, p = 0.03), but did not for the knee joint angle (F1,18 = 0.36, p = 0.56). The functional data analysis, however, found several differences at initial contact (ankle and knee joint), in the mid-stance (each joint) and at toe off (ankle). Although a traditional ANOVA is often appropriate for discrete or summary data, in biomechanical applications, the functional data analysis could be a beneficial alternative. When using the functional data analysis approach, a researcher can (1) evaluate the entire data as a function, and (2) detect the location and magnitude of differences within the evaluated function.

  13. Functional vs. Traditional Analysis in Biomechanical Gait Data: An Alternative Statistical Approach

    Directory of Open Access Journals (Sweden)

    Park Jihong

    2017-12-01

    Full Text Available In human motion studies, discrete points such as peak or average kinematic values are commonly selected to test hypotheses. The purpose of this study was to describe a functional data analysis and describe the advantages of using functional data analyses when compared with a traditional analysis of variance (ANOVA approach. Nineteen healthy participants (age: 22 ± 2 yrs, body height: 1.7 ± 0.1 m, body mass: 73 ± 16 kg walked under two different conditions: control and pain+effusion. Pain+effusion was induced by injection of sterile saline into the joint capsule and hypertonic saline into the infrapatellar fat pad. Sagittal-plane ankle, knee, and hip joint kinematics were recorded and compared following injections using 2×2 mixed model ANOVAs and FANOVAs. The results of ANOVAs detected a condition × time interaction for the peak ankle (F1,18 = 8.56, p = 0.01 and hip joint angle (F1,18 = 5.77, p = 0.03, but did not for the knee joint angle (F1,18 = 0.36, p = 0.56. The functional data analysis, however, found several differences at initial contact (ankle and knee joint, in the mid-stance (each joint and at toe off (ankle. Although a traditional ANOVA is often appropriate for discrete or summary data, in biomechanical applications, the functional data analysis could be a beneficial alternative. When using the functional data analysis approach, a researcher can (1 evaluate the entire data as a function, and (2 detect the location and magnitude of differences within the evaluated function.

  14. Traditional Agroforestry Systems and Food Supply under the Food Sovereignty Approach

    Directory of Open Access Journals (Sweden)

    Mariana Yazzur Hernández

    2017-12-01

    Full Text Available Intensive production systems have damaged many natural ecosystems and have altered their capacity to provide ecosystem services such as climate regulation, soil fertility, and vector-borne disease control. Therefore, these agroecosystems are unsustainable and poorly resilient. However, traditional agroforestry systems (TAS contribute to the conservation of biodiversity and to the provision of inputs for the maintenance of local populations. The objective of this study was to evaluate the contribution of the TAS in the food supply under the food sovereignty (FSv approach in three different ethnic groups. The study was conducted in three communities of different origin in the State of Campeche, one Maya Tseltal-Chol, the other Mestizo, and the third Yucatec Mayan. The theoretical-methodological framework of this research was based on agroecology. Ethnographic methods and participatory research activities were carried out to describe and analyze the factors that strengthen FSv using five indicators. Our results present a description and analysis of resource access, current production models, patterns of consumption and food security, commercialization and participation in decision-making of these communities. Traditional agroecological management practices are still preserved and native species are still being cultivated. Farmers obtain about 55% of their food from TAS. The consumption of food is influenced by the culture, the purchasing power linked to economic activities and government support. TAS have played a strategic role for the survival of families but to ensure their contribution to FSv, it is necessary to articulate the actions of the sectors that share the same objective and encourage the active participation of communities in agricultural policies.

  15. Teaching Research in the Traditional Classroom: Why Make Graduate Students Wait?

    Science.gov (United States)

    Carr, Lincoln D.

    2016-05-01

    Physics graduate programs tend to divide the degree into two parts: (1) theory, taught in classes, almost totally divorced from the lab setting; and (2) research, taught in a research group through hands-on lab experience and mentorship. As we come to understand from undergraduate physics education research that modifying our teaching can rather easily produce quantifiably better results, it is reasonable to ask if we can make similar improvements at the graduate level. In this talk I will present the results of beginning research instruction in the classroom in the very first semester of graduate school, in the most traditional of classes - classical mechanics. In this approach, students build their knowledge from hands-on projects. They get immediately certified and experienced in the machine shop and electronics lab. There are no formal lectures. Students develop and present their own problems, and teach and challenge each other in the classroom. In contrast to polished lectures, both the instructor and the students together learn from their many public mistakes. Students give conference-style presentations instead of exams. As a result, students not only excel in analytical skills, but they also learn to tie theory to measurement, identify statistical and systematic errors, simulate computationally and model theoretically, and design their own experiments. Funded by NSF.

  16. Cross-National Prevalence of Traditional Bullying, Traditional Victimization, Cyberbullying and Cyber-Victimization: Comparing Single-Item and Multiple-Item Approaches of Measurement

    Science.gov (United States)

    Yanagida, Takuya; Gradinger, Petra; Strohmeier, Dagmar; Solomontos-Kountouri, Olga; Trip, Simona; Bora, Carmen

    2016-01-01

    Many large-scale cross-national studies rely on a single-item measurement when comparing prevalence rates of traditional bullying, traditional victimization, cyberbullying, and cyber-victimization between countries. However, the reliability and validity of single-item measurement approaches are highly problematic and might be biased. Data from…

  17. Participatory Research: New Approaches to the Research to Practice Dilemma.

    Science.gov (United States)

    Meyer, Luanna H.; Park, Hyun-Sook; Grenot-Scheyer, Marquita; Schwartz, Ilene; Harry, Beth

    1998-01-01

    This article presents a rationale for incorporating elements of participatory research approaches into intervention research intended to improve practice. After an overview of the research-to-practice problem, it illustrates how the incorporation of participatory research approaches applied to various decision points can enhance the construction…

  18. Traditional, complementary, and alternative medicine approaches to mental health care and psychological wellbeing in India and China.

    Science.gov (United States)

    Thirthalli, Jagadisha; Zhou, Liang; Kumar, Kishore; Gao, Jie; Vaid, Henna; Liu, Huiming; Hankey, Alex; Wang, Guojun; Gangadhar, Bangalore N; Nie, Jing-Bao; Nichter, Mark

    2016-07-01

    India and China face the same challenge of having too few trained psychiatric personnel to manage effectively the substantial burden of mental illness within their population. At the same time, both countries have many practitioners of traditional, complementary, and alternative medicine who are a potential resource for delivery of mental health care. In our paper, part of The Lancet and Lancet Psychiatry's Series about the China-India Mental Health Alliance, we describe and compare types of traditional, complementary, and alternative medicine in India and China. Further, we provide a systematic overview of evidence assessing the effectiveness of these alternative approaches for mental illness and discuss challenges in research. We suggest how practitioners of traditional, complementary, and alternative medicine and mental health professionals might forge collaborative relationships to provide more accessible, affordable, and acceptable mental health care in India and China. A substantial proportion of individuals with mental illness use traditional, complementary, and alternative medicine, either exclusively or with biomedicine, for reasons ranging from faith and cultural congruence to accessibility, cost, and belief that these approaches are safe. Systematic reviews of the effectiveness of traditional, complementary, and alternative medicine find several approaches to be promising for treatment of mental illness, but most clinical trials included in these systematic reviews have methodological limitations. Contemporary methods to establish efficacy and safety-typically through randomised controlled trials-need to be complemented by other means. The community of practice built on collaborative relationships between practitioners of traditional, complementary, and alternative medicine and providers of mental health care holds promise in bridging the treatment gap in mental health care in India and China. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Traditional and Flipped Classroom Approaches Delivered by Two Different Teachers: The Student Perspective

    Science.gov (United States)

    Limniou, Maria; Schermbrucker, Ian; Lyons, Minna

    2018-01-01

    The aim of this investigation was for students to express their views on teaching approaches delivered by two teachers under the perspectives of Higher Order Thinking Skills (HOTS) development, their preferences on learning material and learning activities. First year psychology students followed both the traditional and a flipped classroom…

  20. Surgery-first orthognathic approach vs traditional orthognathic approach: Oral health-related quality of life assessed with 2 questionnaires.

    Science.gov (United States)

    Pelo, Sandro; Gasparini, Giulio; Garagiola, Umberto; Cordaro, Massimo; Di Nardo, Francesco; Staderini, Edoardo; Patini, Romeo; de Angelis, Paolo; D'Amato, Giuseppe; Saponaro, Gianmarco; Moro, Alessandro

    2017-08-01

    The purposes of the study were to investigate and evaluate the differences detected by the patients between the traditional orthognathic approach and the surgery-first one in terms of level of satisfaction and quality of life. A total of 30 patients who underwent orthognathic surgery for correction of malocclusions were selected and included in this study. Fifteen patients were treated with the conventional orthognathic surgery approach, and 15 patients with the surgery-first approach. Variables were assessed through the Orthognathic Quality of Life Questionnaire and the Oral Health Impact Profile questionnaire and analyzed with 2-way repeated-measures analysis of variance. The results showed significant differences in terms of the Orthognathic Quality of Life Questionnaire (P surgery in the surgery-first group and an initial worsening during orthodontic treatment in the traditional approach group followed by postoperative improvement. This study showed that the worsening of the facial profile during the traditional orthognathic surgery approach decompensation phase has a negative impact on the perception of patients' quality of life. Surgeons should consider the possibility of a surgery-first approach to prevent this occurrence. Copyright © 2017 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  1. Research Methodology: A Practitioner Approach

    Science.gov (United States)

    Singh, Sukhpal; Chana, Inderveer; Singh, Maninder

    2015-01-01

    The ultimate goal of scientific research is publication so as to showcase the research outcomes. Scientists, starting as graduate students, are measured primarily not by their dexterity in laboratory manipulations, not by their innate knowledge of either broad or narrow scientific subjects, and certainly not by their wit or charm; they are…

  2. [Applications of mathematical statistics methods on compatibility researches of traditional Chinese medicines formulae].

    Science.gov (United States)

    Mai, Lan-Yin; Li, Yi-Xuan; Chen, Yong; Xie, Zhen; Li, Jie; Zhong, Ming-Yu

    2014-05-01

    The compatibility of traditional Chinese medicines (TCMs) formulae containing enormous information, is a complex component system. Applications of mathematical statistics methods on the compatibility researches of traditional Chinese medicines formulae have great significance for promoting the modernization of traditional Chinese medicines and improving clinical efficacies and optimizations of formulae. As a tool for quantitative analysis, data inference and exploring inherent rules of substances, the mathematical statistics method can be used to reveal the working mechanisms of the compatibility of traditional Chinese medicines formulae in qualitatively and quantitatively. By reviewing studies based on the applications of mathematical statistics methods, this paper were summarized from perspective of dosages optimization, efficacies and changes of chemical components as well as the rules of incompatibility and contraindication of formulae, will provide the references for further studying and revealing the working mechanisms and the connotations of traditional Chinese medicines.

  3. A Comparison of Traditional Book Reviews and Amazon.com Book Reviews of Fiction Using a Content Analysis Approach

    Directory of Open Access Journals (Sweden)

    Christy Sich

    2017-03-01

    Full Text Available Objective - This study compared the quality and helpfulness of traditional book review sources with the online user rating system in Amazon.com in order to determine if one mode is superior to the other and should be used by library selectors to assist in making purchasing decisions. Methods - For this study, 228 reviews of 7 different novels were analyzed using a content analysis approach. Of these, 127 reviews came from traditional review sources and 101 reviews were published on Amazon.com. Results - Using a checklist developed for this study, a significant difference in the quality of reviews was discovered. Reviews from traditional sources scored significantly higher than reviews from Amazon.com. The researcher also looked at review length. On average, Amazon.com reviews are shorter than reviews from traditional sources. Review rating—favourable, unfavourable, or mixed/neutral—also showed a lack of consistency between the two modes of reviews. Conclusion - Although Amazon.com provides multiple reviews of a book on one convenient site, traditional sources of professionally written reviews would most likely save librarians more time in making purchasing decisions, given the higher quality of the review assessment.

  4. Semantic ambiguity effects on traditional Chinese character naming: A corpus-based approach.

    Science.gov (United States)

    Chang, Ya-Ning; Lee, Chia-Ying

    2017-11-09

    Words are considered semantically ambiguous if they have more than one meaning and can be used in multiple contexts. A number of recent studies have provided objective ambiguity measures by using a corpus-based approach and have demonstrated ambiguity advantages in both naming and lexical decision tasks. Although the predictive power of objective ambiguity measures has been examined in several alphabetic language systems, the effects in logographic languages remain unclear. Moreover, most ambiguity measures do not explicitly address how the various contexts associated with a given word relate to each other. To explore these issues, we computed the contextual diversity (Adelman, Brown, & Quesada, Psychological Science, 17; 814-823, 2006) and semantic ambiguity (Hoffman, Lambon Ralph, & Rogers, Behavior Research Methods, 45; 718-730, 2013) of traditional Chinese single-character words based on the Academia Sinica Balanced Corpus, where contextual diversity was used to evaluate the present semantic space. We then derived a novel ambiguity measure, namely semantic variability, by computing the distance properties of the distinct clusters grouped by the contexts that contained a given word. We demonstrated that semantic variability was superior to semantic diversity in accounting for the variance in naming response times, suggesting that considering the substructure of the various contexts associated with a given word can provide a relatively fine scale of ambiguity information for a word. All of the context and ambiguity measures for 2,418 Chinese single-character words are provided as supplementary materials.

  5. Hormesis as a mechanistic approach to understanding herbal treatments in traditional Chinese medicine.

    Science.gov (United States)

    Wang, Dali; Calabrese, Edward J; Lian, Baoling; Lin, Zhifen; Calabrese, Vittorio

    2018-04-01

    Traditional Chinese medicine (TCM) has been long practiced and is becoming ever more widely recognized as providing curative and/or healing treatments for a number of diseases and physiological conditions. This paper posits that herbal medicines used in TCM treatments may act through hormetic dose-response mechanisms. It is proposed that the stimulatory (i.e., low dose) and inhibitory (i.e., high dose) components of the hormetic dose response correspond to respective "regulating" and "curing" aspects of TCM herbal treatments. Specifically, the "regulating" functions promote adaptive or preventive responses, while "curing" treatments alleviate the clinical symptoms. Patterns of hormetic responses are described, and the applicability of these processes to herbal medicines of TCM are explicated. It is noted that a research agenda aimed at elucidating these mechanisms and patterns would be expansive and complex. However, we argue its value, in that hormesis may afford something akin to a Rosetta Stone with which to interpret, translate, and explain TCM herbology in ways that are aligned with biomedical perspectives that could enable a more integrative approach to medicine. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Parametric model measurement: reframing traditional measurement ideas in neuropsychological practice and research.

    Science.gov (United States)

    Brown, Gregory G; Thomas, Michael L; Patt, Virginie

    Neuropsychology is an applied measurement field with its psychometric work primarily built upon classical test theory (CTT). We describe a series of psychometric models to supplement the use of CTT in neuropsychological research and test development. We introduce increasingly complex psychometric models as measurement algebras, which include model parameters that represent abilities and item properties. Within this framework of parametric model measurement (PMM), neuropsychological assessment involves the estimation of model parameters with ability parameter values assuming the role of test 'scores'. Moreover, the traditional notion of measurement error is replaced by the notion of parameter estimation error, and the definition of reliability becomes linked to notions of item and test information. The more complex PMM approaches incorporate into the assessment of neuropsychological performance formal parametric models of behavior validated in the experimental psychology literature, along with item parameters. These PMM approaches endorse the use of experimental manipulations of model parameters to assess a test's construct representation. Strengths and weaknesses of these models are evaluated by their implications for measurement error conditional upon ability level, sensitivity to sample characteristics, computational challenges to parameter estimation, and construct validity. A family of parametric psychometric models can be used to assess latent processes of interest to neuropsychologists. By modeling latent abilities at the item level, psychometric studies in neuropsychology can investigate construct validity and measurement precision within a single framework and contribute to a unification of statistical methods within the framework of generalized latent variable modeling.

  7. Videoethnographic approaches to audience research

    DEFF Research Database (Denmark)

    Wildermuth, Norbert

    recordings in doing mediaethnographic audience research. Moreover, I will discuss the use and potentials of hypermedia in presenting the results of ethnographic audience research. Based on recent conceptualisations and theories of hypermodality and multimodal ethnography (Lemke, 2002; Idema, 2003; Dicks......  In my paper I will explore the methodological uses and epistemological consequences of videoethnography in audience studies. With reference to research done on young people and their media appropriations in Recife (Brazil), in December 2005, I will argue for the creative integration of video......'. Finally, considerations regarding a planned hypermediated presentation of my research project in Recife, will be related to the experiences made with video as tool of mediaethnographic investigation and analysis. How the potential of non-sequentiality enshrined in hypermedia applications can...

  8. [Application of digital earth technology in research of traditional Chinese medicine resources].

    Science.gov (United States)

    Liu, Jinxin; Liu, Xinxin; Gao, Lu; Wei, Yingqin; Meng, Fanyun; Wang, Yongyan

    2011-02-01

    This paper describes the digital earth technology and its core technology-"3S" integration technology. The advance and promotion of the "3S" technology provide more favorable means and technical support for Chinese medicine resources survey, evaluation and appropriate zoning. Grid is a mature and popular technology that can connect all kinds of information resources. The author sums up the application of digital earth technology in the research of traditional Chinese medicine resources in recent years, and proposes the new method and technical route of investigation in traditional Chinese medicine resources, traditional Chinese medicine zoning and suitability assessment by combining the digital earth technology and grid.

  9. Institutions’ Research: an Interdisciplinary Approach

    Directory of Open Access Journals (Sweden)

    Natalia Petrovna Ryzhova

    2014-12-01

    Full Text Available The paper brings together study by economists and anthropologists and aims at a critical investigation of the competing theoretical explanation of the role of violence and beliefs in economic, social and political development. By reconstructing discussion in neo-institutional economic theory over the role of history and culture in current economic performance of under-developed countries, the paper claims that scholars must today pay attention on violence and beliefs. Although economists recently confirmed that these two factors played crucial role in the different development of nations, when some of them accumulate power and wealth, while others fail, the paper argues that more complicated approach is needed. In particular, economists use too simplistic conception of power and violence and refuse to pay attention on beliefs of ordinary people. Social anthropology could suggest both sophisticated approaches to violence and precise attention to ordinary people beliefs. That the reason why anthropological knowledge should be incorporated in neoinstitutional economic theory

  10. Actively Teaching Research Methods with a Process Oriented Guided Inquiry Learning Approach

    Science.gov (United States)

    Mullins, Mary H.

    2017-01-01

    Active learning approaches have shown to improve student learning outcomes and improve the experience of students in the classroom. This article compares a Process Oriented Guided Inquiry Learning style approach to a more traditional teaching method in an undergraduate research methods course. Moving from a more traditional learning environment to…

  11. A Comparison of Classification Approaches for Cyberbullying and Traditional Bullying Using Data from Six European Countries

    Science.gov (United States)

    Schultze-Krumbholz, Anja; Göbel, Kristin; Scheithauer, Herbert; Brighi, Antonella; Guarini, Annalisa; Tsorbatzoudis, Haralambos; Barkoukis, Vassilis; Pyzalski, Jacek; Plichta, Piotr; Del Rey, Rosario; Casas, José A.; Thompson, Fran; Smith, Peter K.

    2015-01-01

    In recently published studies on cyberbullying, students are frequently categorized into distinct (cyber)bully and (cyber)victim clusters based on theoretical assumptions and arbitrary cut-off scores adapted from traditional bullying research. The present study identified involvement classes empirically using latent class analysis (LCA), to…

  12. Blended Design Approach of Long Span Structure and Malay Traditional Architecture

    Science.gov (United States)

    Sundari, Titin

    2017-12-01

    The growing population in the world is so fast, which is followed by the increasing need of some new and large activities. Architects face the problem on how to facilitate buildings with various activities such as for large meeting, conference, indoors gymnasium and sports, and many others. The long span structure of building is one of the solutions to solve that problem. Generally, large buildings which implemented this structure will look as a technological, modern and futuristic ones or even neo futuristic performance. But on the other hand, many people still want to enjoy the specific and unique senses of local traditional architecture. So is the Malay people who want an easy pleasant large facilities which can be fulfilled by implementing modern long span building structure technology. In the same time, their unique sense of Malay traditional architecture can still be maintained. To overcome this double problems of design, it needs a blended design approach of long span structure and Malay Traditional Architecture.

  13. Traditional Chinese medicine research in the post-genomic era: good practice, priorities, challenges and opportunities.

    Science.gov (United States)

    Uzuner, Halil; Bauer, Rudolf; Fan, Tai-Ping; Guo, De-An; Dias, Alberto; El-Nezami, Hani; Efferth, Thomas; Williamson, Elizabeth M; Heinrich, Michael; Robinson, Nicola; Hylands, Peter J; Hendry, Bruce M; Cheng, Yung-Chi; Xu, Qihe

    2012-04-10

    GP-TCM is the 1st EU-funded Coordination Action consortium dedicated to traditional Chinese medicine (TCM) research. This paper aims to summarise the objectives, structure and activities of the consortium and introduces the position of the consortium regarding good practice, priorities, challenges and opportunities in TCM research. Serving as the introductory paper for the GP-TCM Journal of Ethnopharmacology special issue, this paper describes the roadmap of this special issue and reports how the main outputs of the ten GP-TCM work packages are integrated, and have led to consortium-wide conclusions. Literature studies, opinion polls and discussions among consortium members and stakeholders. By January 2012, through 3 years of team building, the GP-TCM consortium had grown into a large collaborative network involving ∼200 scientists from 24 countries and 107 institutions. Consortium members had worked closely to address good practice issues related to various aspects of Chinese herbal medicine (CHM) and acupuncture research, the focus of this Journal of Ethnopharmacology special issue, leading to state-of-the-art reports, guidelines and consensus on the application of omics technologies in TCM research. In addition, through an online survey open to GP-TCM members and non-members, we polled opinions on grand priorities, challenges and opportunities in TCM research. Based on the poll, although consortium members and non-members had diverse opinions on the major challenges in the field, both groups agreed that high-quality efficacy/effectiveness and mechanistic studies are grand priorities and that the TCM legacy in general and its management of chronic diseases in particular represent grand opportunities. Consortium members cast their votes of confidence in omics and systems biology approaches to TCM research and believed that quality and pharmacovigilance of TCM products are not only grand priorities, but also grand challenges. Non-members, however, gave priority

  14. Teaching medical students a clinical approach to altered mental status: simulation enhances traditional curriculum

    Directory of Open Access Journals (Sweden)

    Jeremy D. Sperling

    2013-04-01

    Full Text Available Introduction: Simulation-based medical education (SBME is increasingly being utilized for teaching clinical skills in undergraduate medical education. Studies have evaluated the impact of adding SBME to third- and fourth-year curriculum; however, very little research has assessed its efficacy for teaching clinical skills in pre-clerkship coursework. To measure the impact of a simulation exercise during a pre-clinical curriculum, a simulation session was added to a pre-clerkship course at our medical school where the clinical approach to altered mental status (AMS is traditionally taught using a lecture and an interactive case-based session in a small group format. The objective was to measure simulation's impact on students’ knowledge acquisition, comfort, and perceived competence with regards to the AMS patient. Methods: AMS simulation exercises were added to the lecture and small group case sessions in June 2010 and 2011. Simulation sessions consisted of two clinical cases using a high-fidelity full-body simulator followed by a faculty debriefing after each case. Student participation in a simulation session was voluntary. Students who did and did not participate in a simulation session completed a post-test to assess knowledge and a survey to understand comfort and perceived competence in their approach to AMS. Results: A total of 154 students completed the post-test and survey and 65 (42% attended a simulation session. Post-test scores were higher in students who attended a simulation session compared to those who did not (p<0.001. Students who participated in a simulation session were more comfortable in their overall approach to treating AMS patients (p=0.05. They were also more likely to state that they could articulate a differential diagnosis (p=0.03, know what initial diagnostic tests are needed (p=0.01, and understand what interventions are useful in the first few minutes (p=0.003. Students who participated in a simulation session

  15. Empirical Phenomenology: A Qualitative Research Approach (The ...

    African Journals Online (AJOL)

    Empirical Phenomenology: A Qualitative Research Approach (The Cologne Seminars) ... and practical application of empirical phenomenology in social research. ... and considers its implications for qualitative methods such as interviewing ...

  16. [Research progress of Chinese herbal medicine and traditional Chinese medicine resulting in liver injury].

    Science.gov (United States)

    Wang, Jingli; Zhou, Chaofan

    2011-12-01

    The adverse reactions caused by Chinese herbal medicine and traditional Chinese medicine are reported increased in recent years, among which the acute liver injury caused by Chinese herbal medicine accounts for 21.5% of total liver injuries. Despite the misuse of traditional Chinese medicine not in accordance with differentiation of symptoms and signs, the adverse reaction of Chinese herbal medicine itself can't be little to these adverse events. The paper summarizes the most common categories of traditional Chinese medicine resulting in liver injury, the mechanism, pathological characteristics, clinical symptom of liver injury, the reasons of the reaction and how to prevent. The research aims to enhance the clinical physician recognition of liver injury caused by Chinese herbal medicine, in order to ensure the safe and rational usage of traditional Chinese medicine.

  17. Design science research as research approach in doctoral studies

    CSIR Research Space (South Africa)

    Kotzé, P

    2015-08-01

    Full Text Available Since the use of design science research (DSR) gained momentum as a research approach in information systems (IS), the adoption of a DSR approach in postgraduate studies became more acceptable. This paper reflects on a study to investigate how a...

  18. Application of metabonomic analytical techniques in the modernization and toxicology research of traditional Chinese medicine.

    Science.gov (United States)

    Lao, Yong-Min; Jiang, Jian-Guo; Yan, Lu

    2009-08-01

    In the recent years, a wide range of metabonomic analytical techniques are widely used in the modern research of traditional Chinese medicine (TCM). At the same time, the international community has attached increasing importance to TCM toxicity problems. Thus, many studies have been implemented to investigate the toxicity mechanisms of TCM. Among these studies, many metabonomic-based methods have been implemented to facilitate TCM toxicity investigation. At present, the most prevailing methods for TCM toxicity research are mainly single analysis techniques using only one analytical means. These techniques include nuclear magnetic resonance (NMR), gas chromatography-mass spectrometry (GC-MS), and liquid chromatography-mass spectrometry (LC-MS), etc.; with these techniques, some favourable outcomes have been gained in the toxic reaction studies of TCM, such as the action target organs assay, the establishment of action pattern, the elucidation of action mechanism and the exploration of action material foundation. However, every analytical technique has its advantages and drawbacks, no existing analytical technique can be versatile. Multi-analysed techniques can partially overcome the shortcomings of single-analysed techniques. Combination of GC-MS and LC-MS metabolic profiling approaches has unravelled the pathological outcomes of aristolochic acid-induced nephrotoxicity, which can not be achieved by single-analysed techniques. It is believed that with the further development of metabonomic analytical techniques, especially multi-analysed techniques, metabonomics will greatly promote TCM toxicity research and be beneficial to the modernization of TCM in terms of extending the application of modern means in the TCM safety assessment, assisting the formulation of TCM safety norms and establishing the international standards indicators.

  19. Experimental design research approaches, perspectives, applications

    CERN Document Server

    Stanković, Tino; Štorga, Mario

    2016-01-01

    This book presents a new, multidisciplinary perspective on and paradigm for integrative experimental design research. It addresses various perspectives on methods, analysis and overall research approach, and how they can be synthesized to advance understanding of design. It explores the foundations of experimental approaches and their utility in this domain, and brings together analytical approaches to promote an integrated understanding. The book also investigates where these approaches lead to and how they link design research more fully with other disciplines (e.g. psychology, cognition, sociology, computer science, management). Above all, the book emphasizes the integrative nature of design research in terms of the methods, theories, and units of study—from the individual to the organizational level. Although this approach offers many advantages, it has inherently led to a situation in current research practice where methods are diverging and integration between individual, team and organizational under...

  20. Crocodile years: the traditional image of science and physical scientists' participation in weapons research

    Energy Technology Data Exchange (ETDEWEB)

    Crews, R.J.

    1985-01-01

    This thesis examines one dimension of the relationship between science and the arms race. More specifically, it develops and empirically examines a theoretical model of the relationship between the social demand for defense-related and weapons research, traditional scientific values related to the worldview of classical physics, and differential participation by physical scientists in such research. The theoretical model suggests that an antiquated traditional image of science exists, and that it may explain, in part, participation by physical scientists in defense-related or weapons research. Two major hypotheses are suggested by the model: first, that a constellation of values representing a traditional image of science obtains today among young physical scientists; and second, that those who currently engage (or are willing to engage) in defense-related or weapons research are more likely to agree with the values implicit in the traditional image of science than those who do not (or would not) engage in such research. The theoretical model is located within the sociologies of knowledge and science. This study includes chapters that provide an overview of the literature of these subdisciplines. This investigation concludes with an empirical examination of the model and hypotheses.

  1. Evidence based practice in traditional & complementary medicine: An agenda for policy, practice, education and research.

    Science.gov (United States)

    Leach, Matthew J; Canaway, Rachel; Hunter, Jennifer

    2018-05-01

    To develop a policy, practice, education and research agenda for evidence-based practice (EBP) in traditional and complementary medicine (T&CM). The study was a secondary analysis of qualitative data, using the method of roundtable discussion. The sample comprised seventeen experts in EBP and T&CM. The discussion was audio-recorded, and the transcript analysed using thematic analysis. Four central themes emerged from the data; understanding evidence and EBP, drivers of change, interpersonal interaction, and moving forward. Captured within these themes were fifteen sub-themes. These themes/sub-themes translated into three broad calls to action: (1) defining terminology, (2) defining the EBP approach, and (3) fostering social movement. These calls to action formed the framework of the agenda. This analysis presents a potential framework for an agenda to improve EBP implementation in T&CM. The fundamental elements of this action plan seek clarification, leadership and unification on the issue of EBP in T&CM. Copyright © 2018 Elsevier Ltd. All rights reserved.

  2. The critical assessment of research traditional and new methods of evaluation

    CERN Document Server

    Bailin, Alan

    2010-01-01

    This book examines the following factors: sponsorship of research, control of the dissemination of research, effects of dominant research paradigms, financial interests of authors, publishers, and editors, role of new technologies (for example, Web 2.0).It is widely accepted among researchers and educators that the peer review process, the reputation of the publisher and examination of the author's credentials are the gold standards for assessing the quality of research and information. However, the traditional gold standards are not sufficient, and the effective evaluation of information req

  3. Natural ecosystem mimicry in traditional dryland agroecosystems: Insights from an empirical and holistic approach.

    Science.gov (United States)

    Blanco, Julien; Michon, Geneviève; Carrière, Stéphanie M

    2017-12-15

    While the aim of Ecological Intensification is to enable the design of more sustainable and productive agricultural systems, it is not suited to dryland agroecosystems that are driven by non-equilibrium dynamics and intrinsic variability. Instead, a model based on mobility and variability management has been proposed for these agroecosystems. However, this model remains under-applied in southern Morocco where there have been few studies on the functioning of traditional agroecosystems. This paper focuses on an agroecosystem in the Moroccan Saharan fringe zone that combines agriculture and pastoralism in an acacia parkland. A grounded theory approach was used over a three-year investigation period (i) to highlight how agro-pastoral activities interface with environmental variability, and (ii) to analyze the formal and informal institutions that support these activities. Results show that farmers interface with rainfall variability through (i) an opportunistic agricultural calendar, (ii) a variation of cultivated areas, and (iii) crop diversification. Herders combine macro-mobility (nomads move over long distances to track rainfall) and micro-mobility (nomadic and sedentary herds are driven on a daily basis around settlements) to optimize the exploitation of ecological heterogeneity. During droughts, they also resort to State-subsidized forage supplies. Both cultivation and pastoral activities tend to interface with ecological dynamics and to mimic nature, resulting in a human-modified parkland that could be considered as a 'green agroecosystem'. The sustainability of natural resource use relies on flexible property rights, backed up by a social and cultural norm-based regulation system, that allow crop-livestock integration and landscape collective management. Despite encouraging results, the agroecosystem appears to be threatened by current agricultural policies, rural exodus and the lack of social recognition of nomadism. Nevertheless, because ecosystem mimicry of

  4. System versus traditional approach in road traffic injury prevention. A call for action

    Directory of Open Access Journals (Sweden)

    Davoud Khorasani-Zavareh

    2011-07-01

    Full Text Available Road traffic injuries (RTIs are a major public health problem worldwide, especially in low- and middle-income countries (LMICsand require concerted efforts for effective and sustainable prevention. A variety of measures need to be considered when planning activities. This is particularly true in LMICs. Iran, for example, despite its enormous efforts in recent years in both pre-crash and post crash measures as well as social policy changes, continues to be challenged by the sheer magnitude of this major public health problem. Accordingly, stakeholders’ perceptions, the approach and the kind of preventive activities are crucial. On the whole, there are two different approaches in RTI prevention: the individual approach and the system approach.In the individual approach, there is a tendency for researchers and particularly practitioners to identify only one or a few elements, which usually can be found in many LMICs. Traditionally, in such countries many studies have focused on factors relating to driver errors, poor vehicles and the road environment instead of finding the reason for injury outcome. In many LMICs, the majority of preventive activities target road-user behaviors, which are usually tackled by means of education and enforcement. Hence the primary responsibility is assigned to the road user. However, while safe road-user behavior is one important component, changing such behavior should not simply be focused on education and enforcement. When WHO launched its call to action, it invited members of the public to be part of the solution. The initiative focused on five important courses of action for the general public including: not speeding; wearing a seat-belt; being visible on the road; wearing a helmet; and never drinking and driving. Studies on public education efficiency have revealed that a decrease in crashes due to such campaigns can occur only if they clearly target specific forms of behavior, like seat belt use or helmet

  5. A case study in serendipity: environmental researchers use of traditional and social media for dissemination.

    Science.gov (United States)

    Wilkinson, Clare; Weitkamp, Emma

    2013-01-01

    In the face of demands for researchers to engage more actively with a wider range of publics and to capture different kinds of research impacts and engagements, we explored the ways a small number of environmental researchers use traditional and social media to disseminate research. A questionnaire was developed to investigate the impact of different media as a tool to broker contact between researchers and a variety of different stakeholders (for example, publics, other researchers, policymakers, journalists) as well as how researchers perceive that their use of these media has changed over the past five years. The questionnaire was sent to 504 researchers whose work had featured in a policy-oriented e-news service. 149 valid responses were received (29%). Coverage in traditional media (newspapers, broadcast) not only brokers contact with other journalists, but is a good source of contact from other researchers (n=47, 62%) and members of the public (n=36, 26%). Although the use of social media was limited amongst our sample, it did broker contact with other researchers (n=17, 47%) and the public (n=10, 28%). Nevertheless, few environmental researchers were actively using social media to disseminate their research findings, with many continuing to rely on academic journals and face-to-face communication to reach both academic and public audiences.

  6. A case study in serendipity: environmental researchers use of traditional and social media for dissemination.

    Directory of Open Access Journals (Sweden)

    Clare Wilkinson

    Full Text Available In the face of demands for researchers to engage more actively with a wider range of publics and to capture different kinds of research impacts and engagements, we explored the ways a small number of environmental researchers use traditional and social media to disseminate research. A questionnaire was developed to investigate the impact of different media as a tool to broker contact between researchers and a variety of different stakeholders (for example, publics, other researchers, policymakers, journalists as well as how researchers perceive that their use of these media has changed over the past five years. The questionnaire was sent to 504 researchers whose work had featured in a policy-oriented e-news service. 149 valid responses were received (29%. Coverage in traditional media (newspapers, broadcast not only brokers contact with other journalists, but is a good source of contact from other researchers (n=47, 62% and members of the public (n=36, 26%. Although the use of social media was limited amongst our sample, it did broker contact with other researchers (n=17, 47% and the public (n=10, 28%. Nevertheless, few environmental researchers were actively using social media to disseminate their research findings, with many continuing to rely on academic journals and face-to-face communication to reach both academic and public audiences.

  7. Traditional Japanese Kampo Medicine: Clinical Research between Modernity and Traditional Medicine—The State of Research and Methodological Suggestions for the Future

    Directory of Open Access Journals (Sweden)

    Kenji Watanabe

    2011-01-01

    Full Text Available The Japanese traditional herbal medicine, Kampo, has gradually reemerged and 148 different formulations (mainly herbal extracts can be prescribed within the national health insurance system. The objective of this article is to introduce Kampo and to present information from previous clinical studies that tested Kampo formulae. In addition, suggestions on the design of future research will be stated. The literature search was based on a summary, up until January 2009, by the Japanese Society of Oriental Medicine and included only those trials which were also available in either Pubmed or ICHUSHI (Japan Medical Abstracts Society. We included 135 studies, half of these studies (n=68 used a standard control and 28 a placebo control. Thirty-seven trials were published in English [all randomized controlled trials (RCTs] and the remaining articles were in Japanese only. The sample size for most studies was small (two-third of the studies included less than 100 patients and the overall methodological quality appeared to be low. None of the studies used Kampo diagnosis as the basis for the treatment. In order to evaluate Kampo as a whole treatment system, certain aspects should be taken into account while designing studies. RCTs are the appropriate study design to test efficacy or effectiveness; however, within the trial the treatment could be individualized according to the Kampo diagnosis. Kampo is a complex and individualized treatment with a long tradition, and it would be appropriate for further research on Kampo medicine to take this into account.

  8. Design and Implementation of Collaborative Research Approaches

    Science.gov (United States)

    Venti, Mike W.; Berger, David E.

    2009-01-01

    This poster reviews the collarborative research approaches that NASA has been designing and implementing for the Integrated Vehicle Health Management (IVHM) Project. The inputs for the technical plan are reviewed, the Research Test and Integration Plan (RTIP) WIKI, is used to create and propose a multi-themed and multi-partner research testing opportunities. The outputs are testing opportunities.

  9. State Traditions and Language Regimes: A Historical Institutionalism Approach to Language Policy

    Directory of Open Access Journals (Sweden)

    Sonntag Selma K.

    2015-12-01

    Full Text Available This paper is an elaboration of a theoretical framework we developed in the introductory chapter of our co-edited volume, State Traditions and Language Regimes (McGill-Queen’s University Press, 2015. Using a historical institutionalism approach derived from political science, we argue that language policies need to be understood in terms of their historical and institutional context. The concept of ‘state tradition’ focuses our attention on the relative autonomy of the state in terms of its normative and institutional traditions that lead to particular path dependencies of language policy choices, subject to change at critical junctures. ‘Language regime’ is the conceptual link between state traditions and language policy choices: it allows us to analytically conceptualize how and why these choices are made and how and why they change. We suggest that our framework offers a more robust analysis of language politics than other approaches found in sociolinguistics and normative theory. It also challenges political science to become more engaged with scholarly debate on language policy and linguistic diversity.

  10. How psychology affects decisions in corporate finance: Traditional vs. behavioural approach

    OpenAIRE

    Luca Piras

    2012-01-01

    The aim of this research is to draw a theoretical line to connect on a common conceptual base, behavioural fi-nance with what is internationally known as Modern Fi-nance. The debate often involves discussions about the prevalence of rationality over irrationality. This paper will address mainly two questions: as an economist, should I propend for traditional or for behavioural finance? And, perhaps more important, are they in opposition to each other? Linking the principles upon which the tra...

  11. COMPARATIVE STUDY BETWEEN TRADITIONAL AND ENTERPRISE RISK MANAGEMENT -A THEORETICAL APPROACH

    Directory of Open Access Journals (Sweden)

    Cican Simona-Iulia

    2014-07-01

    Full Text Available The complexity, volatility and unpredictability of the current economic environment are a daily reminder that organizations face many risks. The traditional approach, according to which risk is a necessary evil which must be removed, is no longer sufficient and that is why companies nowadays are forced to spend significant resources to manage risks. Risk transparency is what one looks for; therefore, identification and management of risks within an organization become increasingly necessary for success and longevity. Risk approach has a major role in a company’s ability to avoid, reduce and turn risks into opportunities. Enterprise risk management is a new concept that revolutionizes the traditional approach and summarizes risk management in an integrated, comprehensive and strategic system. Studies use several synonyms for enterprise risk management such as integrated risk management, holistic risk management, global risk management and strategic risk management. Enterprise risk management implements at the end of the last century a new way to deal with risks: the holistic approach. This risks approach – i.e. interaction of several types of risks which become increasingly threatening and varied and may cause more damage than individual risk – brings forward the need of risk management and raises issues at the highest level of company management. For a proper view on company risks, each individual risk and the possibility of risk interaction must be understood. This is essential to establish a risk classification according to their impact on the company. Traditional approach on risk management, as a management function, is limited to only threats and losses, so relatively few organizations see risks as potential earning-generated opportunities. However, risk management process is not radically changed. Enterprise risk management is an improved version of the traditional risk management, created by expanding its scope. The new risk

  12. Research progress of traditional Chinese medicine extract for retinal ischemia-reperfusion injury

    Directory of Open Access Journals (Sweden)

    Qian-Yu Jia

    2015-05-01

    Full Text Available Retinal ischemia-reperfusion injury(RIRIis a common clinical disease, and the producing mechanism is still in research. Experimental and clinical research in recent years have showed that the mechanism of RIRI and oxygen free radicals, gene regulation, calcium overload, inflammatory cytokines and other factors are closely related. In this article, we summarized the current situation that the scholars at home and abroad study traditional Chinese medicine extract of prevention and treatment of RIRI.

  13. Prospecting for bioactive constituents from traditional medicinal plants through ethnobotanical approaches.

    Science.gov (United States)

    Gu, Ronghui; Wang, Yuehu; Long, Bo; Kennelly, Edward; Wu, Shibiao; Liu, Bo; Li, Ping; Long, Chunlin

    2014-01-01

    Pharmacologically active constituents from traditional medicinal plants have received great attention as sources of novel agents, pharmaceutical intermediates, and chemical entities for synthetic or semisynthetic drugs due to their potent pharmacological activities, low toxicity, and economic viability. Numerous components have been isolated from traditional medicinal plants, including alkaloids, flavonoids, and terpenoids, and clinical and experimental studies suggested that these components have useful pharmacological properties such as antiinfectious, antioxidative, and antiinflammatory effects. In this review, modern ethnobotanical approaches to explore folk medicinal plants as candidates for drug discovery with the greatest possibility of success are discussed. Determining the bioactive mechanisms and tracing structure-activity relationships will promote the discovery of new drugs and pharmacological agents.

  14. Comparative Analysis of Automatic Exudate Detection between Machine Learning and Traditional Approaches

    Science.gov (United States)

    Sopharak, Akara; Uyyanonvara, Bunyarit; Barman, Sarah; Williamson, Thomas

    To prevent blindness from diabetic retinopathy, periodic screening and early diagnosis are neccessary. Due to lack of expert ophthalmologists in rural area, automated early exudate (one of visible sign of diabetic retinopathy) detection could help to reduce the number of blindness in diabetic patients. Traditional automatic exudate detection methods are based on specific parameter configuration, while the machine learning approaches which seems more flexible may be computationally high cost. A comparative analysis of traditional and machine learning of exudates detection, namely, mathematical morphology, fuzzy c-means clustering, naive Bayesian classifier, Support Vector Machine and Nearest Neighbor classifier are presented. Detected exudates are validated with expert ophthalmologists' hand-drawn ground-truths. The sensitivity, specificity, precision, accuracy and time complexity of each method are also compared.

  15. USING QUALITATIVE APPROACH IN SPECIAL EDUCATION RESEARCH

    Directory of Open Access Journals (Sweden)

    Natasa GALEVSKA

    1998-04-01

    Full Text Available The text deals with some methodological problems in special education research. The limits of purely positivistic, quantitative, experimental research in the area of special education lately are overcome with the use of qualitative approach. Qualitative research are flexibly designed. The data are descriptive and collected in natural setting. Characteristics of the qualitative research make them more appropriate for investigation of the phenomena in special education, considering the small numbers of available subjects, heterogeneity, ethical and moral problems, etc.

  16. Flight Test Approach to Adaptive Control Research

    Science.gov (United States)

    Pavlock, Kate Maureen; Less, James L.; Larson, David Nils

    2011-01-01

    The National Aeronautics and Space Administration s Dryden Flight Research Center completed flight testing of adaptive controls research on a full-scale F-18 testbed. The validation of adaptive controls has the potential to enhance safety in the presence of adverse conditions such as structural damage or control surface failures. This paper describes the research interface architecture, risk mitigations, flight test approach and lessons learned of adaptive controls research.

  17. [Advances in diabetic animal models and its application in the traditional Chinese medicine research].

    Science.gov (United States)

    Cheng, Long; Shen, Zhu-fang; Sun, Gui-bo; Sun, Xiao-bo

    2015-08-01

    The high and continuing soaring incidence of diabetes may become a huge obstacle to China's development. The antidiabetic drug development is one way to solve the problem. Animal model is a powerful tool for drug development. This paper compares and analyzes the three kinds of animal models for antidiabetic drug development in replicating principle, methods and characteristic, then summarized the application in the research of traditional Chinese medicine. At the same time, the analysis of the market, application and clinical advantages of hypoglycemic medicine from traditional Chinese medicine, is given in this paper, based on the literature analysis. From the point of the clinic advantage embodiment and new drug development, this paper will provide advisory and assistance support for the anti-diabetic fighting with traditional Chinese medicine.

  18. Research progress on high altitude retinopathy and application of Traditional Chinese Medicine

    Directory of Open Access Journals (Sweden)

    Hai-Xiang Huang

    2014-11-01

    Full Text Available High altitude retinopathy(HARrefers to the body which can't adapt to the hypobaric hypoxia environment at high altitude leading to retinal diseases, which typically manifested as retinal hemorrhages, optic disc edema and cotton wool spots. With the development of high altitude medicine, HAR become a hot topic of eye research in recent years. New researches show a significantly higher incidence of HAR, and HAR has a close contact with acute mountain sickness, high altitude cerebral edema and high altitude pulmonary edema. A further study in pathogenesis and prevention measures of HAR will promote the prevention of altitude sickness. Traditional Chinese Medicine has achieved good effects in the prevention of altitude sickness, but the effect and mechanism of herbs on HAR has not been reported. Through read and summarize the relevant literatures and reports, the author will give an overview of the research advances on HAR's pathogenesis and application of Traditional Chinese Medicine.

  19. [Research on promotory effect of traditional Chinese medicine on fracture healing in cell and molecular level].

    Science.gov (United States)

    Zhang, Kun; Niu, Liang-Chen; Yuan, Fu-Jie; Liu, Shen-Peng

    2017-08-25

    Traditional Chinese medicine is widely used in the treatment of fractures, osteoporosis, other bone related diseases for thousands of years. There are many animal experiments and clinical trials demonstrating that the traditional Chinese medicine such as epimedium, Drynaria and other traditional Chinese medicine can stimulate bone regeneration and inhibit bone resorption, accelerating the fracture healing. In recent years many cell experiments have shown that these herbal ingredients up-regulated the expression of intracellular osteogenic transcription factors and osteogenic related genes, and then induced osteoblastic differentiation and stimulated the proliferation of osteoblasts, bone nodule formation and matrix mineralization. Meanwhile these herbal ingredients up-regulated the expression of intracellular osteoclastic transcription factors and osteoclast related genes, inhibited osteoclast differentiation and bone resorption of osteoclasts. In addition, intracellular signaling pathways regulated these herbal ingredients by might be involved in the above effects. We can have a conclusion that the genes expression regulated by transcription factors in pre-osteoblast and pre-osteoclast and these signaling pathways are the major molecular mechanisms and research hotspots of traditional Chinese medicine in promoting fracture healing. Based on these molecular mechanisms to review, this review provides not only the foundation for the study of traditional Chinese medicine in promoting fracture healing, but also the basis for clinical treatment of fracture. Copyright© 2017 by the China Journal of Orthopaedics and Traumatology Press.

  20. GABAA receptor binding molecules from traditional Chinese Medicine: An in silico approach

    Directory of Open Access Journals (Sweden)

    Meng Lv

    2014-12-01

    Full Text Available The advents of how anesthesia works have helped in the discovery of anesthetic target protein. One such target protein named ϒ-aminobutyric acid (GABAA, which is the chief inhibitory neurotransmitter in the mammalian central nervous system. Asparagine at 289 position of GABAA protein within TM2 is important for its anesthetic function. This study explores Traditional Chinese Medicine (TCM against ASN 289 of GABAA for novel anesthetic compounds. The in silico approach showed gastrodin out of all compounds to be the best compound to start further analysis. It is a potential anesthetic compound suitable for the development of new drug.

  1. [Traditional and modern approaches to culture of preimplantation mammalian embryos in vitro].

    Science.gov (United States)

    Brusentsev, E Iu; Igonina, T N; Amstislavskiĭ, S Ia

    2014-01-01

    This review covers the basic principles and methods of in vitro culture of preimplantation mammalian embryos. The features of in vitro development of embryos of various species of animals with allowance for the composition of nutrient media are described, with special attention paid to those species that have traditionally been consideredas laboratory (i.e., mice, rats, and hamsters). The effects of suboptimal culturing conditions of preimplantation embryos on the formation of the phenotype of individuals developed from these embryos are discussed. New approaches to optimize the conditions of the development of preimplantation mammalian embryos in vitro are analyzed.

  2. Managing and monitoring tuberculosis using web-based tools in combination with traditional approaches.

    Science.gov (United States)

    Chapman, Ann Ln; Darton, Thomas C; Foster, Rachel A

    2013-01-01

    Tuberculosis (TB) remains a global health emergency. Ongoing challenges include the coordination of national and international control programs, high levels of drug resistance in many parts of the world, and availability of accurate and rapid diagnostic tests. The increasing availability and reliability of Internet access throughout both affluent and resource-limited countries brings new opportunities to improve TB management and control through the integration of web-based technologies with traditional approaches. In this review, we explore current and potential future use of web-based tools in the areas of TB diagnosis, treatment, epidemiology, service monitoring, and teaching and training.

  3. Theoretical basis, application, reliability, and sample size estimates of a Meridian Energy Analysis Device for Traditional Chinese Medicine Research

    Directory of Open Access Journals (Sweden)

    Ming-Yen Tsai

    Full Text Available OBJECTIVES: The Meridian Energy Analysis Device is currently a popular tool in the scientific research of meridian electrophysiology. In this field, it is generally believed that measuring the electrical conductivity of meridians provides information about the balance of bioenergy or Qi-blood in the body. METHODS AND RESULTS: PubMed database based on some original articles from 1956 to 2014 and the authoŕs clinical experience. In this short communication, we provide clinical examples of Meridian Energy Analysis Device application, especially in the field of traditional Chinese medicine, discuss the reliability of the measurements, and put the values obtained into context by considering items of considerable variability and by estimating sample size. CONCLUSION: The Meridian Energy Analysis Device is making a valuable contribution to the diagnosis of Qi-blood dysfunction. It can be assessed from short-term and long-term meridian bioenergy recordings. It is one of the few methods that allow outpatient traditional Chinese medicine diagnosis, monitoring the progress, therapeutic effect and evaluation of patient prognosis. The holistic approaches underlying the practice of traditional Chinese medicine and new trends in modern medicine toward the use of objective instruments require in-depth knowledge of the mechanisms of meridian energy, and the Meridian Energy Analysis Device can feasibly be used for understanding and interpreting traditional Chinese medicine theory, especially in view of its expansion in Western countries.

  4. The Influence of Traditional Culture and the Interpersonal Psychological Theory on Suicide Research in Korea.

    Science.gov (United States)

    Park, Yeonsoo; Baik, Seung Yeon; Kim, Hyang-Sook; Lee, Seung-Hwan

    2017-11-01

    Korea has the highest suicide rate amongst the OECD countries. Yet, its research on suicidal behaviors has been primitive. While the Interpersonal Psychological Theory of Suicide has gained global attention, there has only been a few researches, which examined its applicability in Korea. In this article, we review the previous studies on suicide and examine the association between the Interpersonal Psychological Theory of Suicide and traditional Korean culture, with an emphasis on Collectivism and Confucianism. We propose that pathways to suicide might vary depending on cultural influences. Clinical implications and suggestions for future research will be discussed.

  5. Implementation of Research and Development Based on Patent Natural Ingredients and Potential Utilization of Tradition Medicine

    Directory of Open Access Journals (Sweden)

    Tommy Hendrix

    2016-12-01

    Full Text Available The results of research and development based on natural ingredients for traditional medicines become an interesting topic to discuss at this point; it’s shown from increasing number in utilization. The use of traditional medicine especially on natural ingredients at this moment becomes effective solution to increase the level of market acceptance in herbal extracts, including an affordable purchase from potential utilization of natural resources which are owned. By using Matheo Patent XE Ver 10.2 as methodology of searching, we can know potentials useful through strategy, research and development, patent analysis and patent collaboration among users in utilization of Natural Ingredient for Traditional Medicine. From the data result shows majority in the field of chemistry for human necessity related to Health; Amusement; Medical or Veterinary Science; Hygiene sectors with total patent 108, family 65. The use of patent analysis is a way to find how the development of technology and products that have been produced and how commercial processes connecting with technology users, especially in traditional medicine. From the data that exist in particular of patents, it is critical to identify the number of patents that has been registered through the innovation process development including technology dissemination is used.

  6. Ultrasonography-guided peripheral intravenous access versus traditional approaches in patients with difficult intravenous access.

    Science.gov (United States)

    Costantino, Thomas G; Parikh, Aman K; Satz, Wayne A; Fojtik, John P

    2005-11-01

    We assess the success rate of emergency physicians in placing peripheral intravenous catheters in difficult-access patients who were unsuccessfully cannulated by emergency nurses. A technique using real-time ultrasonographic guidance by 2 physicians was compared with traditional approaches using palpation and landmark guidance. This was a prospective, systematically allocated study of all patients requiring intravenous access who presented to 2 university hospitals between October 2003 and March 2004. Inclusion criterion was the inability of any available nurse to obtain intravenous access after at least 3 attempts on a subgroup of patients who had a history of difficult intravenous access because of obesity, history of intravenous drug abuse, or chronic medical problems. Exclusion criterion was the need for central venous access. Patients presenting on odd days were allocated to the ultrasonographic-guided group, and those presenting on even days were allocated to the traditional-approach group. Endpoints were successful cannulation, number of sticks, time, and patient satisfaction. Sixty patients were enrolled, 39 on odd days and 21 on even days. Success rate was greater for the ultrasonographic group (97%) versus control (33%), difference in proportions of 64% (95% confidence interval [CI] 39% to 71%). The ultrasonographic group required less overall time (13 minutes versus 30 minutes, for a difference of 17 [95% CI 0.8 to 25.6]), less time to successful cannulation from first percutaneous puncture (4 minutes versus 15 minutes, for a difference of 11 [95% CI 8.2 to 19.4]), and fewer percutaneous punctures (1.7 versus 3.7, for a difference of 2.0 [95% CI 1.27 to 2.82]) and had greater patient satisfaction (8.7 versus 5.7, for a difference of 3.0 [95% CI 1.82 to 4.29]) than the traditional landmark approach. Ultrasonographic-guided peripheral intravenous access is more successful than traditional "blind" techniques, requires less time, decreases the number of

  7. [Application of chemometrics in composition-activity relationship research of traditional Chinese medicine].

    Science.gov (United States)

    Han, Sheng-Nan

    2014-07-01

    Chemometrics is a new branch of chemistry which is widely applied to various fields of analytical chemistry. Chemometrics can use theories and methods of mathematics, statistics, computer science and other related disciplines to optimize the chemical measurement process and maximize access to acquire chemical information and other information on material systems by analyzing chemical measurement data. In recent years, traditional Chinese medicine has attracted widespread attention. In the research of traditional Chinese medicine, it has been a key problem that how to interpret the relationship between various chemical components and its efficacy, which seriously restricts the modernization of Chinese medicine. As chemometrics brings the multivariate analysis methods into the chemical research, it has been applied as an effective research tool in the composition-activity relationship research of Chinese medicine. This article reviews the applications of chemometrics methods in the composition-activity relationship research in recent years. The applications of multivariate statistical analysis methods (such as regression analysis, correlation analysis, principal component analysis, etc. ) and artificial neural network (such as back propagation artificial neural network, radical basis function neural network, support vector machine, etc. ) are summarized, including the brief fundamental principles, the research contents and the advantages and disadvantages. Finally, the existing main problems and prospects of its future researches are proposed.

  8. A novel recruiting and surveying method: Participatory research during a Pacific Islander community’s traditional cultural event

    Directory of Open Access Journals (Sweden)

    Grace Donoho

    2015-09-01

    Full Text Available Little is known about the health status of Marshallese, a Pacific Islander subpopulation living in the United States. The Marshallese have established a growing community in Northwest Arkansas, providing a unique opportunity for increasing knowledge regarding the health of this minority group. This article describes how a community-based participatory research process was used by a community and university coalition to identify and refine questionnaires and recruit study participants. Questionnaires were self-administered on computers during a one-week traditional cultural event. A total of 874 Marshallese from Arkansas completed the questionnaire, exceeding the goal of 600 respondents. Lessons learned, including the level and timing of involvement of both the leadership and the community at large, are discussed in detail. This approach enhanced communication and collaboration between the Marshallese community, service providers and researchers, resulting in higher participation and interest among the Marshallese community. Keywords: participatory research, minority populations, community health assessment, community coalition, Marshallese

  9. Persian Medicine in the World of Research; Review of Articles on Iranian Traditional Medicine.

    Science.gov (United States)

    Moeini, Reihaneh; Gorji, Narjes

    2016-05-01

    Due to negligence, Persian (Iranian) traditional medicine has had a weak presence in the world of research for a long time. However, in recent years, a variety of activates by research and faculty centers have created awareness and a platform to introduce and promote Persian medicine to the world. The aim of this study is to present and analyze scientific achievements of Persian medicine in the world of research. Articles were collected from PubMed database using keywords such as "Persian medicine", "Persian traditional medicine", "Iranian medicine", and "Iranian traditional medicine". All data were classified based on the type of research (review, intervention, case reports, etc.), the field of study (neurology, cardiovascular, metabolic, historical studies, etc.), publication year, and journal type. A total of 501 articles were identified until the end of 2015, comprising of 222 reviews and 219 interventional (108 animal, 57 clinical and 54 cellular). Most studies were on neurology (20.1%), gastroenterology (14.5%), and cardiovascular diseases (10.4%). The publications in 2015 and 2014 had the highest hit rate with 139 and 132 articles, respectively, with 1:2 publication ratio between foreign and Iranian journals. The most published articles, both foreign and Iranian, were in "Evidence-Based Complementary and Alternative Medicine" and "Iranian Red Crescent Medicine" journals. The contribution of foreign authors was 5%. The primary focus of the articles was on "Basic concepts of Persian medicine", "Healthy lifestyle according to Persian medicine", and "Historical aspects", by 3.1%, 2.9%, and 6.7%, respectively. During the last 2 years, the number of articles published in Persian (Iranian) medicine, particularly clinical studies had significant growth in comparison with the years before. The tendency of foreign researchers to use the keywords "Iranian" or "Persian" medicine is notable. This research was only based on the designated keyword and other keywords were

  10. What Are the Main Drivers of Young Consumers Purchasing Traditional Food Products? European Field Research

    Science.gov (United States)

    Kyrgiakos, Leonidas

    2018-01-01

    In this research, the attitude of European young adults (age 18 to 30 years) regarding their consumption of local and traditional products was examined. The survey was conducted on a sample of 836 consumers from seven European countries (Greece, Bulgaria, Romania, Slovenia, Croatia, Denmark and France). Data collection was made by distributing a developed questionnaire through social media and university mail services. Principal Component Analysis (PCA) was used to identify consumer perception comparing the overall sample with two subsets (consumers from Eastern and Western European countries). Six major factors were revealed: consumer behavior, uncertainty about health issues, cost, influence of media and friends and availability in store. Young adults had a positive attitude to local and traditional food products, but they expressed insecurity about health issues. Cost factor had less of an influence on interviewees from Eastern European countries than those from the overall sample (3rd and 5th factor accordingly). Influence of close environment was a different factor in Eastern countries compared to Western ones, for which it was common to see an influence from media. Females and older people (25–30 years old) have fewer doubts about Traditional Food Products, while media have a high influence on consumers’ decisions. The aim of this survey was to identify the consumer profiles of young adults and create different promotion strategies of local and traditional products among the two groups of countries. PMID:29439536

  11. What Are the Main Drivers of Young Consumers Purchasing Traditional Food Products? European Field Research

    Directory of Open Access Journals (Sweden)

    George Vlontzos

    2018-02-01

    Full Text Available In this research, the attitude of European young adults (age 18 to 30 years regarding their consumption of local and traditional products was examined. The survey was conducted on a sample of 836 consumers from seven European countries (Greece, Bulgaria, Romania, Slovenia, Croatia, Denmark and France. Data collection was made by distributing a developed questionnaire through social media and university mail services. Principal Component Analysis (PCA was used to identify consumer perception comparing the overall sample with two subsets (consumers from Eastern and Western European countries. Six major factors were revealed: consumer behavior, uncertainty about health issues, cost, influence of media and friends and availability in store. Young adults had a positive attitude to local and traditional food products, but they expressed insecurity about health issues. Cost factor had less of an influence on interviewees from Eastern European countries than those from the overall sample (3rd and 5th factor accordingly. Influence of close environment was a different factor in Eastern countries compared to Western ones, for which it was common to see an influence from media. Females and older people (25–30 years old have fewer doubts about Traditional Food Products, while media have a high influence on consumers’ decisions. The aim of this survey was to identify the consumer profiles of young adults and create different promotion strategies of local and traditional products among the two groups of countries.

  12. Conceptualizing strategic environmental assessment: Principles, approaches and research directions

    Energy Technology Data Exchange (ETDEWEB)

    Noble, Bram, E-mail: b.noble@usask.ca [Department of Geography and Planning, and School of Environment and Sustainability, University of Saskatchewan, 117 Science Place, Saskatoon, Saskatchewan S7N 5A5 (Canada); Nwanekezie, Kelechi [Department of Geography and Planning, University of Saskatchewan, 117 Science Place, Saskatoon, Saskatchewan S7N 5A5 (Canada)

    2017-01-15

    Increasing emphasis has been placed in recent years on transitioning strategic environmental assessment (SEA) away from its environmental impact assessment (EIA) roots. Scholars have argued the need to conceptualize SEA as a process designed to facilitate strategic thinking, thus enabling transitions toward sustainability. The practice of SEA, however, remains deeply rooted in the EIA tradition and scholars and practitioners often appear divided on the nature and purpose of SEA. This paper revisits the strategic principles of SEA and conceptualizes SEA as a multi-faceted and multi-dimensional assessment process. It is suggested that SEA can be conceptualized as series of approaches operating along a spectrum from less to more strategic – from impact assessment-based to strategy-based – with each approach to SEA differentiated by the specific objectives of SEA application and the extent to which strategic principles are reflected in its design and implementation. Advancing the effectiveness of SEA requires a continued research agenda focused on improving the traditional SEA approach, as a tool to assess the impacts of policies, plans and programs (PPPs). Realizing the full potential of SEA, however, requires a new research agenda — one focused on the development and testing of a deliberative governance approach to SEA that can facilitate strategic innovations in PPP formulation and drive transitions in short-term policy and initiatives based on longer-term thinking. - Highlights: • SEA facilitates strategic thinking, enabling transitions toward sustainability. • SEA is conceptualized as a spectrum of approaches, from IA-based to strategy-based. • Each approach variably emphasizes strategic principles in its design and practice. • There is no one conceptualization of SEA that is best, SEA is fit for PPP purpose. • Research is needed to advance SEA to facilitate strategic PPP transformations.

  13. Conceptualizing strategic environmental assessment: Principles, approaches and research directions

    International Nuclear Information System (INIS)

    Noble, Bram; Nwanekezie, Kelechi

    2017-01-01

    Increasing emphasis has been placed in recent years on transitioning strategic environmental assessment (SEA) away from its environmental impact assessment (EIA) roots. Scholars have argued the need to conceptualize SEA as a process designed to facilitate strategic thinking, thus enabling transitions toward sustainability. The practice of SEA, however, remains deeply rooted in the EIA tradition and scholars and practitioners often appear divided on the nature and purpose of SEA. This paper revisits the strategic principles of SEA and conceptualizes SEA as a multi-faceted and multi-dimensional assessment process. It is suggested that SEA can be conceptualized as series of approaches operating along a spectrum from less to more strategic – from impact assessment-based to strategy-based – with each approach to SEA differentiated by the specific objectives of SEA application and the extent to which strategic principles are reflected in its design and implementation. Advancing the effectiveness of SEA requires a continued research agenda focused on improving the traditional SEA approach, as a tool to assess the impacts of policies, plans and programs (PPPs). Realizing the full potential of SEA, however, requires a new research agenda — one focused on the development and testing of a deliberative governance approach to SEA that can facilitate strategic innovations in PPP formulation and drive transitions in short-term policy and initiatives based on longer-term thinking. - Highlights: • SEA facilitates strategic thinking, enabling transitions toward sustainability. • SEA is conceptualized as a spectrum of approaches, from IA-based to strategy-based. • Each approach variably emphasizes strategic principles in its design and practice. • There is no one conceptualization of SEA that is best, SEA is fit for PPP purpose. • Research is needed to advance SEA to facilitate strategic PPP transformations.

  14. How psychology affects decisions in corporate finance: Traditional vs. behavioural approach

    Directory of Open Access Journals (Sweden)

    Luca Piras

    2012-11-01

    Full Text Available The aim of this research is to draw a theoretical line to connect on a common conceptual base, behavioural fi-nance with what is internationally known as Modern Fi-nance. The debate often involves discussions about the prevalence of rationality over irrationality. This paper will address mainly two questions: as an economist, should I propend for traditional or for behavioural finance? And, perhaps more important, are they in opposition to each other? Linking the principles upon which the traditional theory of finance is based to behavioural finance appears also to be useful to better understand recent global turmoil in the world financial system. In finding such links, behavioural finance studies will help on driving research to define market models much closer to reality than they are today. Thus literature recognition will be carried out, starting from the most important contribution to fundamental analysis, value theory, going through modern portfolio theory and efficient market hypothesis to seminal contributions on behavioural finance, reaching recent findings of Neuronomics, in order to establish some common theoretical base in corporate finance studies.

  15. Current mass spectrometry approaches and challenges for the bioanalysis of traditional Chinese medicines.

    Science.gov (United States)

    Dong, Xin; Wang, Rui; Zhou, Xu; Li, Ping; Yang, Hua

    2016-07-15

    Traditional Chinese medicines (TCMs) are gaining more and more attentions all over the world. The focus of TCMs researches were gradually shifted from chemical research to the combination study of chemical and life sciences. However, obtaining precise information of TCMs process in vivo or in vitro is still a bottleneck in bioanalysis of TCMs for their chemical composition complexity. This paper reviewed the recent analytical methods especially mass spectrometry technology in the bioanalysis of TCMs, and data processing techniques in the qualitative and quantitative analyses of metabolite of TCMs. Additionally, the difficulties encountered in the analyzing biological samples in TCMs and the solutions to these problems have been mentioned. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. ETHNOGRAPHIC APPROACH TO EFL/ESL RESEARCH

    Directory of Open Access Journals (Sweden)

    Nikolaus Pasassung

    2016-10-01

    Full Text Available This article shows that ethnography, as an approach, is a very useful tool to be applied in research attempting a good understanding of EFL/ESL classrooms. With reference to work done by anthropologists and classroom researchers, the pre- sent article argues that education, including EFL/ESL classrooms, can be well un- derstood by using ethnographic  approaches.  This is done by elaborating  the rele- vance of ethnography and the classroom context in the sense that ethnographic prin- ciples are applicable in describing and understanding the culture of a classroom, and EFL/ESL teaching in particular.

  17. Clinical Research on Traditional Chinese Medicine compounds and their preparations for Amyotrophic Lateral Sclerosis.

    Science.gov (United States)

    Zhu, Jiayi; Shen, Lan; Lin, Xiao; Hong, Yanlong; Feng, Yi

    2017-12-01

    Amyotrophic lateral sclerosis (ALS) is a chronic, fatal neurodegenerative disease which leads to progressive muscle atrophy and paralysis. In order to summarize the characteristics of Traditional Chinese Medicine compounds and their preparations in the prevention and treatment of ALS through analyzing the mechanism, action site, and symptoms according to effective clinical research. We searched ALS, motor neuron disease, chemical drugs, herbal medicine, Chinese medicine, Traditional Chinese Medicine (TCM), and various combinations of these terms in databases including the PudMed, Springer, Ovid, Google, China National Knowledge Infrastructure, and Wanfang databases. It was found that the chemical drugs almost had not sufficient evidence to show their effectiveness in the treatment of ALS, except RILUZOLE. According to the characteristics of clinical symptoms of ALS, Chinese medicine practitioners believe that this disease belongs to the category of "atrophic disease". In clinical research, many Chinese herbal formulas had good clinical efficacies in the treatment of ALS with multiple targets, multiple links, and few side effects. And four kinds of dialectical treatment had been developed based on Clinical data analysis and the use of dialectical therapy: Benefiting the kidney; Declaring the lungs; Enhancing the Qi; and Dredging the meridian. In this review, we provide an overview of chemical drugs and Traditional Chinese Medicine compound and its preparations in therapy of ALS as well as how they may contribute to the ALS pathogenesis, thereby offering some clues for further studies. Copyright © 2017. Published by Elsevier Masson SAS.

  18. Identification of Potential Biomarkers from Aconitum carmichaelii, a Traditional Chinese Medicine, Using a Metabolomic Approach.

    Science.gov (United States)

    Zhao, Dake; Shi, Yana; Zhu, Xinyan; Liu, Li; Ji, Pengzhang; Long, Chunlin; Shen, Yong; Kennelly, Edward J

    2018-04-01

    Despite their well-known toxicity, Aconitum species are important traditional medicines worldwide. Aconitum carmichaelii , known in Chinese as (fuzi), is an officially recognized traditional Chinese medicine with characteristic analgesic and anti-inflammatory activities, whose principal pharmacological ingredients are considered as aconitine-type diterpene alkaloids. Notwithstanding the long-recorded use of A. carmichaelii in traditional Chinese medicine, no single-entity aconitum alkaloid drug has been developed for clinical use. UPLC-Q-TOF-MS was used to investigate the marker compounds that can be used to differentiate A. carmichaelii from seven other Aconitum species collected in Yunnan Province. Nontargeted principle component analysis scores plots found that all the tested Aconitum species clustered into three distinct groups, and A. carmichaelii was significantly different chemically than the other seven species. Furthermore, the primary and lateral roots of A. carmichaelii also showed significant differences. Using orthogonal partial least squares discriminate analysis analysis, eight marker compounds were identified, including 14-acetylkarakoline, aconitine, carmichaeline, fuziline, hypaconitine, mesaconitine, neoline, and talatisamine. Four of these aconitum alkaloids, fuziline, hypaconitine, mesaconitine, and neoline, showed significant analgesic activity in a dose-dependent manner compared to the negative and positive controls. However, hypaconitine, mesaconitine, and neoline exhibited significant acute toxicity activity, while fuziline showed no acute toxicity in mice, suggesting the relative safety of this alkaloid. This study provides a good example of how to differentiate an authentic medicinal plant from common adulterants using a metabolomics approach, and to identify compounds that may be developed into new drugs. Georg Thieme Verlag KG Stuttgart · New York.

  19. Proteomic approaches in research of cyanobacterial photosynthesis.

    Science.gov (United States)

    Battchikova, Natalia; Angeleri, Martina; Aro, Eva-Mari

    2015-10-01

    Oxygenic photosynthesis in cyanobacteria, algae, and plants is carried out by a fabulous pigment-protein machinery that is amazingly complicated in structure and function. Many different approaches have been undertaken to characterize the most important aspects of photosynthesis, and proteomics has become the essential component in this research. Here we describe various methods which have been used in proteomic research of cyanobacteria, and demonstrate how proteomics is implemented into on-going studies of photosynthesis in cyanobacterial cells.

  20. A partnership approach to research data management

    OpenAIRE

    Brown, Mark L.; White, Wendy

    2013-01-01

    This outlines developments to support and enhance research data management policy and practice at the University of Southampton. It details a research-led approach to identify institutional challenges and priorities and use of this evidence-base to inform the creation of a 10 year roadmap and policy framework. The particular issues relating to workflow, storage, security and archiving are discussed and examples are given of both pilot and embedded services including data management planning s...

  1. Managing and monitoring tuberculosis using web-based tools in combination with traditional approaches

    Directory of Open Access Journals (Sweden)

    Chapman AL

    2013-11-01

    Full Text Available Ann LN Chapman,1 Thomas C Darton,2 Rachel A Foster11Department of Infection and Tropical Medicine, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, 2Oxford Vaccine Group, Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UKAbstract: Tuberculosis (TB remains a global health emergency. Ongoing challenges include the coordination of national and international control programs, high levels of drug resistance in many parts of the world, and availability of accurate and rapid diagnostic tests. The increasing availability and reliability of Internet access throughout both affluent and resource-limited countries brings new opportunities to improve TB management and control through the integration of web-based technologies with traditional approaches. In this review, we explore current and potential future use of web-based tools in the areas of TB diagnosis, treatment, epidemiology, service monitoring, and teaching and training.Keywords: tuberculosis, information communication technology, Internet

  2. Nurses' maths: researching a practical approach.

    Science.gov (United States)

    Wilson, Ann

    To compare a new practical maths test with a written maths test. The tests were undertaken by qualified nurses training for intravenous drug administration, a skill dependent on maths accuracy. The literature showed that the higher education institutes (HEIs) that provide nurse training use traditional maths tests, a practical way of testing maths had not been described. Fifty five nurses undertook two maths tests based on intravenous drug calculations. One was a traditional written test. The second was a new type of test using a simulated clinical environment. All participants were also interviewed one week later to ascertain their thoughts and feelings about the tests. There was a significant improvement in maths test scores for those nurses who took the practical maths test first. It is suggested that this is because it improved their conceptualisation skills and thus helped them to achieve accuracy in their calculations. Written maths tests are not the best way to help and support nurses in acquiring and improving their maths skills and should be replaced by a more practical approach.

  3. The Ethics of Traditional Chinese and Western Herbal Medicine Research: Views of Researchers and Human Ethics Committees in Australia

    Directory of Open Access Journals (Sweden)

    Caroline A. Smith

    2011-01-01

    Full Text Available Despite the growth of traditional Chinese medicine (TCM and western herbal medicine (WHM research in Australia, little is known about how ethics committees (HRECs assess the ethics of TCM or WHM research. The objectives of this study were to examine the experiences of TCM and WHM researchers and HRECs with the evaluation of ethics applications. Two cross-sectional surveys were undertaken of HRECs and TCM and WHM researchers in Australia. Anonymous self-completion questionnaires were administered to 224 HRECs and 117 researchers. A response confirming involvement in TCM or WHM research applications was received from 20 HRECs and 42 researchers. The most frequent ethical issues identified by HRECs related to herbal products including information gaps relating to mode of action of herbal medicines and safety when combining herbal ingredients. Researchers concurred that they were frequently requested to provide additional information on multiple aspects including safety relating to the side effects of herbs and herb-drug interactions. Overall adherence with the principles of ethical conduct was high among TCM and WHM researchers although our study did identify the need for additional information regarding assessment of risk and risk management.

  4. DNA barcoding and traditional taxonomy: an integrated approach for biodiversity conservation.

    Science.gov (United States)

    Sheth, Bhavisha P; Thaker, Vrinda S

    2017-07-01

    Biological diversity is depleting at an alarming rate. Additionally, a vast amount of biodiversity still remains undiscovered. Taxonomy has been serving the purpose of describing, naming, and classifying species for more than 250 years. DNA taxonomy and barcoding have accelerated the rate of this process, thereby providing a tool for conservation practice. DNA barcoding and traditional taxonomy have their own inherent merits and demerits. The synergistic use of both methods, in the form of integrative taxonomy, has the potential to contribute to biodiversity conservation in a pragmatic timeframe and overcome their individual drawbacks. In this review, we discuss the basics of both these methods of biological identification (traditional taxonomy and DNA barcoding), the technical advances in integrative taxonomy, and future trends. We also present a comprehensive compilation of published examples of integrative taxonomy that refer to nine topics within biodiversity conservation. Morphological and molecular species limits were observed to be congruent in ∼41% of the 58 source studies. The majority of the studies highlighted the description of cryptic diversity through the use of molecular data, whereas research areas like endemism, biological invasion, and threatened species were less discussed in the literature.

  5. Expert knowledge maps for knowledge management: a case study in Traditional Chinese Medicine research.

    Science.gov (United States)

    Cui, Meng; Yang, Shuo; Yu, Tong; Yang, Ce; Gao, Yonghong; Zhu, Haiyan

    2013-10-01

    To design a model to capture information on the state and trends of knowledge creation, at both an individual and an organizational level, in order to enhance knowledge management. We designed a graph-theoretic knowledge model, the expert knowledge map (EKM), based on literature-based annotation. A case study in the domain of Traditional Chinese Medicine research was used to illustrate the usefulness of the model. The EKM successfully captured various aspects of knowledge and enhanced knowledge management within the case-study organization through the provision of knowledge graphs, expert graphs, and expert-knowledge biography. Our model could help to reveal the hot topics, trends, and products of the research done by an organization. It can potentially be used to facilitate knowledge learning, sharing and decision-making among researchers, academicians, students, and administrators of organizations.

  6. The Rise and Tide of the Minangkabau Traditional Trading in Kuala Lumpur: A Preliminary Research

    Directory of Open Access Journals (Sweden)

    Sismudjito .

    2015-06-01

    Full Text Available This article is discussing on how the rise and tide of Minangkabau traditional trading occur in Kuala Lumpur. The research focused on four areas in Kuala Lumpur, Chow Kit, Kampung Baru, Kampung Dato’ Keramat and Mesjid India area, reveals that there are some small stalls of Minangkabau  traditional trading are now owned by another Indonesian ethnicity such as Acehenese and Boyanese tribe. Meanwhile, some of the businesses are still possessed by Minangkabau tribe such as Nasi Padang and textile trading. The phenomenon is affected by the lack of business innovation, capital, local competitor and the fact that they are unable to follow the trend in business. Even though,  there are some of well-developed traditional business run by Minangkabau people in Kuala Lumpur due to the existence of marketing creativity, innovative items, and the conducive partnership with another Minangkabau entrepreneurs in the textile merchant  in form of kiosk or  arcade in Mesjid India area that has connection with another counterpart of the  nationwide  including Sabah and Sarawak.

  7. Research advances in the treatment of Alzheimer's disease with polysaccharides from traditional Chinese medicine.

    Science.gov (United States)

    Liu, Qin; Wang, Shun-Chun; Ding, Kan

    2017-09-01

    Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the loss of patients' memory and their cognitive abilities and the mechanism is not completely clear. Although a variety of drugs have been approved for the AD treatment, substances which can prevent and cure AD are still in great need. The effect of polysaccharides from traditional Chinese medicine (TCM) on anti-AD has gained great progress and attained more and more attention in recent years. In this review, research advances in TCM-polysaccharides on AD made in this decade are summarized. Copyright © 2017 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.

  8. NITARP: Bridging the Gap Between the Traditional Science Classroom and Authentic Research

    Science.gov (United States)

    Stalnaker, Olivia K.; Evans, Sam; Rutherford, Thomas; Taylor, John; Rebull, Luisa

    2018-01-01

    In this poster, the differences between what occurs in the traditional secondary science classroom and what happens in the actual research world is examined. Secondary classroom teachers generally have limited, if any, research experience beyond what is presented through their undergraduate college lab coursework. A disparity exists between classroom laboratory work and professional research. Opportunities like NITARP provide research elements that bridge this gap. NITARP teams are in a unique situation, joining a small team working alongside Caltech researchers on cutting edge investigations in astrophysics. In this poster it is shown how the NITARP program provides key components and experiences to expand the skill sets that teachers bring to their classrooms, bridging the gap between the typical secondary classroom and the world of the professional researcher. The NASA/IPAC program immerses participating teachers into a year-long training experience via online and face-to-face learning that translates into enhanced instruction at the secondary level. This work was made possible through the NASA/IPAC Teacher Archive Research Program (NITARP) and was funded by NASA Astrophysics Data Program.

  9. Temari Reiki: a new hands-off approach to traditional Reiki.

    Science.gov (United States)

    Townsend, Jane Stewart

    2013-04-01

    This paper encapsulates the history of Reiki, an ancient healing art, from its origins in Japan to current practice in the United States. It defines Reiki therapy and discusses the development of a new Reiki method called Temari Reiki and the use of two additional chakras. Lastly, sample clients scenarios are provided. Because of the success of Temari Reiki in my practice, recommendations include that it be integrated as therapy to augment traditional Western medicine-based patient care plans for patients with cancer, pain, stress and other disabling health issues. Also, additional research using randomized clinical trials is recommended to examine the benefits of Temari Reiki for improving patients' well-being in mind, body and spirit. © 2013 Wiley Publishing Asia Pty Ltd.

  10. New approach of a traditional analysis for predicting near-exit jet liquid instabilities

    Science.gov (United States)

    Jaramillo, Guillermo; Collicott, Steven

    2015-11-01

    Traditional linear instability theory for round liquid jets requires an exit-plane velocity profile be assumed so as to derive the characteristic growth rates and wavelengths of instabilities. This requires solving an eigenvalue problem for the Rayleigh Equation. In this new approach, a hyperbolic tangent velocity profile is assumed at the exit-plane of a round jet and a comparison is made with a hyperbolic secant profile. Temporal and Spatial Stability Analysis (TSA and SSA respectively) are the employed analytical tools to compare results of predicted most-unstable wavelengths from the given analytical velocity profiles and from previous experimental work. The local relevance of the velocity profile in the near-exit region of a liquid jet and the validity of an inviscid formulation through the Rayleigh equation are discussed as well. A comparison of numerical accuracy is made between two different mathematical approaches for the hyperbolic tangent profile with and without the Ricatti transformation. Reynolds number based on the momentum thickness of the boundary layer at the exit plane non-dimensionalizes the problem and, the Re range, based on measurements by Portillo in 2011, is 185 to 600. Wavelength measurements are taken from Portillo's experiment. School of Mechanical Engineering at Universidad del Valle, supported by a grant from Fulbright and Colciencias. Ph.D. student at the School of Aeronautics and Astronautics Purdue University.

  11. Risk assessment of nanomaterials and nanoproducts – adaptation of traditional approaches

    International Nuclear Information System (INIS)

    Jahnel, J; Fleischer, T; Seitz, S B

    2013-01-01

    Different approaches have been adopted for assessing the potential risks of conventional chemicals and products for human health. In general, the traditional paradigm is a toxicological-driven chemical-by-chemical approach, focusing on single toxic endpoints. Scope and responsibilities for the development and implementation of a risk assessment concept vary across sectors and areas and depends on the specific regulatory environment and the specific protection goals. Thus, risk assessment implication is a complex task based not only on science based knowledge but also on the regulatory context involving different parties and stakeholders. Questions have been raised whether standard paradigms for conventional chemicals would be applicable and adequate for new materials, products and applications of nanotechnology. Most scientists and stakeholders assume that current standard methods are in principle applicable to nanomaterials, but specific aspects require further development. The paper presents additional technical improvements like the complementary use of the life cycle methodology and the support of risk-based classification systems. But also aspects improving the utility of risk assessment with regard to societal impacts on risk governance are discussed.

  12. Analyzing Constructions of Polytheistic and Monotheistic Religious Traditions: A Critical Multicultural Approach to Textbooks in Quebec

    Science.gov (United States)

    Abdou, Ehaab D.; Chan, W. Y. Alice

    2017-01-01

    How are religious traditions and exchanges between them constructed in textbooks used in Quebec? Through a critical discourse analysis of History and Citizenship Education, and Ethics and Religious Culture textbooks, we find that the Abrahamic monotheistic tradition is valorized, while non-Abrahamic monotheistic traditions and polytheism are…

  13. Research-based approaches to nuclear education

    Energy Technology Data Exchange (ETDEWEB)

    Donev, J.M.K.C., E-mail: jason.donev@ucalgary.ca [Univ. of Calgary, Calgary, AB (Canada); Carpenter, Y., E-mail: ycarpenter@gmail.com [Univ.ty of Colorado at Boulder, Boulder, CO (United States)

    2014-07-01

    Teaching nuclear power requires an expert to communicate a significant number of abstract concepts from diverse disciplines, and assemble these into a larger intellectual framework for the students. Scholarly education research, particularly in individual science disciplines, has provided significant advances in teaching core subject material by breaking away from traditional lecturing. Thus far, however,little work has applied these results to introductory nuclear power classes. This paper explores a method of engaging introductory nuclear students deeply by using a combination of Socratic and mastery methods of teaching. Students develop conceptual understanding of the material through the group work and the use of diverse resources, including textbooks, online references, and computer models that encourage free exploration of these concepts. Marks have improved considerably, and students engage with the material at a significantly deeper level than in previous lecture-based iterations of this course. (author)

  14. Research-based approaches to nuclear education

    International Nuclear Information System (INIS)

    Donev, J.M.K.C.; Carpenter, Y.

    2014-01-01

    Teaching nuclear power requires an expert to communicate a significant number of abstract concepts from diverse disciplines, and assemble these into a larger intellectual framework for the students. Scholarly education research, particularly in individual science disciplines, has provided significant advances in teaching core subject material by breaking away from traditional lecturing. Thus far, however,little work has applied these results to introductory nuclear power classes. This paper explores a method of engaging introductory nuclear students deeply by using a combination of Socratic and mastery methods of teaching. Students develop conceptual understanding of the material through the group work and the use of diverse resources, including textbooks, online references, and computer models that encourage free exploration of these concepts. Marks have improved considerably, and students engage with the material at a significantly deeper level than in previous lecture-based iterations of this course. (author)

  15. Assessing Health Promotion Interventions: Limitations of Traditional Research Methods in Community-Based Studies.

    Science.gov (United States)

    Dressel, Anne; Schneider, Robert; DeNomie, Melissa; Kusch, Jennifer; Welch, Whitney; Sosa, Mirtha; Yeldell, Sally; Maida, Tatiana; Wineberg, Jessica; Holt, Keith; Bernstein, Rebecca

    2017-09-01

    Most low-income Americans fail to meet physical activity recommendations. Inactivity and poor diet contribute to obesity, a risk factor for multiple chronic diseases. Health promotion activities have the potential to improve health outcomes for low-income populations. Measuring the effectiveness of these activities, however, can be challenging in community settings. A "Biking for Health" study tested the impact of a bicycling intervention on overweight or obese low-income Latino and African American adults to reduce barriers to cycling and increase physical activity and fitness. A randomized controlled trial was conducted in Milwaukee, Wisconsin, in summer 2015. A 12-week bicycling intervention was implemented at two sites with low-income, overweight, or obese Latino and African American adults. We found that randomized controlled trial methodology was suboptimal for use in this small pilot study and that it negatively affected participation. More discussion is needed about the effectiveness of using traditional research methods in community settings to assess the effectiveness of health promotion interventions. Modifications or alternative methods may yield better results. The aim of this article is to discuss the effectiveness and feasibility of using traditional research methods to assess health promotion interventions in community-based settings.

  16. [Research advance in metabolism of effective ingredients from traditional Chinese medicines by probiotics].

    Science.gov (United States)

    Dai, Cheng-En; Li, Hai-Long; He, Xiao-Ping; Zheng, Fen-Fen; Zhu, Hua-Liu; Liu, Liang-Feng; Du, Wei

    2018-01-01

    The pharmacological activity of active ingredients from Chinese medicine depends greatly on the microecological environment of probiotics in the human body. After effective ingredients from traditional Chinese medicines are metabolized or biotransformed by probiotics, their metabolites can increase pharmacological activity, and can be absorbed more easily to improve the bioavailability. Therefore, the combination of Chinese medicines with probiotics is the innovation point in R&D of functional food and Chinese medicines, and also a new thinking for the modernization of Chinese medicine.This review summarizes and analyses the research progress on metabolism effects of gut microbiota on Chinese medicines components, the regulating effect of effective ingredients from Chinese medicine on intestinal probiotics, the application status of probiotics in traditional Chinese medicines, and the main problems and prospects in the research and development of Chinese medicines products with probiotic, aiming to provide theoretical guidance and practical value for the fermentation engineering of Chinese herbal medicine. Copyright© by the Chinese Pharmaceutical Association.

  17. Risk management in medical product development process using traditional FMEA and fuzzy linguistic approach: a case study

    Science.gov (United States)

    Kirkire, Milind Shrikant; Rane, Santosh B.; Jadhav, Jagdish Rajaram

    2015-12-01

    Medical product development (MPD) process is highly multidisciplinary in nature, which increases the complexity and the associated risks. Managing the risks during MPD process is very crucial. The objective of this research is to explore risks during MPD in a dental product manufacturing company and propose a model for risk mitigation during MPD process to minimize failure events. A case study approach is employed. The existing MPD process is mapped with five phases of the customized phase gate process. The activities during each phase of development and risks associated with each activity are identified and categorized based on the source of occurrence. The risks are analyzed using traditional Failure mode and effect analysis (FMEA) and fuzzy FMEA. The results of two methods when compared show that fuzzy approach avoids the duplication of RPNs and helps more to convert cognition of experts into information to get values of risk factors. The critical, moderate, low level and negligible risks are identified based on criticality; risk treatments and mitigation model are proposed. During initial phases of MPD, the risks are less severe, but as the process progresses the severity of risks goes on increasing. The MPD process should be critically designed and simulated to minimize the number of risk events and their severity. To successfully develop the products/devices within the manufacturing companies, the process risk management is very essential. A systematic approach to manage risks during MPD process will lead to the development of medical products with expected quality and reliability. This is the first research of its kind having focus on MPD process risks and its management. The methodology adopted in this paper will help the developers, managers and researchers to have a competitive edge over the other companies by managing the risks during the development process.

  18. The method of quality marker research and quality evaluation of traditional Chinese medicine based on drug properties and effect characteristics.

    Science.gov (United States)

    Zhang, Tiejun; Bai, Gang; Han, Yanqi; Xu, Jun; Gong, Suxiao; Li, Yazhuo; Zhang, Hongbing; Liu, Changxiao

    2018-05-15

    Quality of traditional Chinese medicine (TCM) plays a critical role in industry of TCM. Rapid development of TCM pharmaceutical areas is, however, greatly limited, since there are many issues not been resolved, concerning the quality study of TCM. Core concept of TCM quality as well as the characteristics of TCM was discussed, in order to guide the quality research and evaluation of TCM, further improve the level of TCM quality control. In this review, on the basis of systematic analysis of fundamental property and features of TCM in clinical application, the approaches and methods of quality marker (Q-marker) study were proposed through combination of transitivity and traceability of essentials of quality, correlation between chemical ingredients and drug property/efficacy, as well as analysis of endemicity of ingredients sharing similar pharmacophylogenetic and biosynthetic approaches. The approaches and methods of Q-marker study were proposed and the novel integrated pattern for quality assessment and control of TCM was established. The core concept of Q-marker has helped to break through the bottleneck of the current fragmented quality research of TCM and improved the scientificity, integrity and systematicness of quality control. Copyright © 2018 Elsevier GmbH. All rights reserved.

  19. CONFERENCE CHEVREUL Nutrition research: the industrial approach

    Directory of Open Access Journals (Sweden)

    Korver Onno

    2000-01-01

    Full Text Available The goal of nutrition research in an industrial setting is the marketing of products. Since consumers cannot see from the product whether it is healthy, communication to the consumer about the nutritional and health values of the products is essential. Industrial nutrition research therefore has to provide the scientific dossier to underpin the claims and other communication on and around the product as well as the scientific basis for the communication. These two lines are illustrated in figure 1. For scientific audiences the steps to collect the scientific evidence are obvious: first screening for new ideas on the basis of scientific developments and business options, then identifying ingredients that can deliver the health benefit, followed by mechanistic and bioavailability studies and finally human intervention trials. The communication line is less obvious for most scientifically oriented audiences. Experience has shown that an information cascade has to be followed: during the execution of the research work close contact with academic experts (a true dialogue is essential, when the research data are available information of a wide selection of health professionals (e.g. physicians, dieticians, science journalists is taking place and only after this step communication to the consumer starts. The communication with the scientific experts (the first step of the cascade obviously has to be in the hands of the nutrition research group of the industry involved. In Unilever this is the Unilever Nutrition Centre based in Vlaardingen in the Netherlands. Their role in the scientific dialogue is outlined in figure 2. The fact that the “Medaille Chevreul” has been awarded twice to members of the Unilever Nutrition Centre in the last two decades, illustrates that the UNC is considered to be a group with a truly scientific tradition.

  20. Citizen Hydrology - Tradeoffs between Traditional Continuous Approaches and Temporally Discrete Hydrologic Monitoring

    Science.gov (United States)

    Davids, Jeffrey; Rutten, Martine; van de Giesen, Nick; Mehl, Steffen; Norris, James

    2016-04-01

    Traditional approaches to hydrologic data collection rely on permanent installations of sophisticated and relatively accurate but expensive monitoring equipment at limited numbers of sites. Consequently, the spatial coverage of the data is limited and the cost is high. Moreover, achieving adequate maintenance of the sophisticated equipment often exceeds local technical and resource capacity, and experience has shown that permanently deployed monitoring equipment is susceptible to vandalism, theft, and other hazards. Rather than using expensive, vulnerable installations at a few points, SmartPhones4Water (S4W), a form of citizen science, leverages widely available mobile technology to gather hydrologic data at many sites in a manner that is highly repeatable and scalable. The tradeoff for increased spatial resolution, however, is reduced observation frequency. As a first step towards evaluating the tradeoffs between the traditional continuous monitoring approach and emerging citizen science methods, 50 U.S. Geological Survey (USGS) streamflow gages were randomly selected from the population of roughly 350 USGS gages operated in California. Gaging station metadata and historical 15 minute flow data for the period from 01/10/2007 through 31/12/2014 were compiled for each of the selected gages. Historical 15 minute flow data were then used to develop daily, monthly, and yearly determinations of average, minimum, maximum streamflow, cumulative runoff, and streamflow distribution. These statistics were then compared to similar statistics developed from randomly selected daily and weekly spot measurements of streamflow. Cumulative runoff calculated from daily and weekly observations were within 10 percent of actual runoff calculated from 15 minute data for 75 percent and 46 percent of sites respectively. As anticipated, larger watersheds with less dynamic temporal variability compared more favorably for all statistics evaluated than smaller watersheds. Based on the

  1. [Moderation-integrated-balance presupposition of Chinese medicine compound and pharmacological problems in traditional Chinese drug research].

    Science.gov (United States)

    Zhao, Jun-Ning

    2017-03-01

    The moderation-integrated-balance presupposition (MIBP) of Chinese medicine compound was first proposed in this paper based on the review of function characteristics and action principles of Chinese medicine compound. Furthermore, the pharmacological problems of traditional Chinese drug research were discussed in details. The results were of important value in accelerating the transformation of traditional Chinese medicine compound, and constructing the new drug innovation and review system for traditional Chinese medicine. Copyright© by the Chinese Pharmaceutical Association.

  2. Research Quality Plus (RQ+) A Holistic Approach to Evaluating Research

    Energy Technology Data Exchange (ETDEWEB)

    McLean, R.K.D.; Feinstein, O.N.

    2016-07-01

    The International Development Research Centre (IDRC) strives to fund excellence in research - defining excellence as, {sup m}ethodologically sound, evidence-based, and scientifically robust{sup .} But how is the concept of excellence identified and evaluated across the diverse range of research the IDRC supports? The Research Quality Plus (RQ+) Assessment Framework was developed in order to address these complex issues. It provides a systems-informed approach to defining and evaluating the quality of research, and its positioning for use and impact. It allows tailoring to context, values, mandate and purpose, and can support planning, management and learning processes at any stage in the lifetime of a research project, program or grants portfolio. This paper presents: 1) the rationale for RQ+ creation, 2) the RQ+ Assessment Framework, and how it can be adapted and used, 3) our early experiences applying it in a series of extenal evaluations of research quality. The paper is presented by an RQ+ designer and an external user. (Author)

  3. International development of traditional medicine / complementary and alternative medicine research--what can Europe learn?

    Science.gov (United States)

    Hök, Johanna; Lewith, George; Weidenhammer, Wolfgang; Santos-Rey, Koldo; Fønnebø, Vinjar; Wiesener, Solveig; Falkenberg, Torkel

    2012-01-01

    The aim of this study was to analyse global research and development (R&D) strategies for traditional medicine (TM) and complementary and alternative medicine (CAM) across the world to learn from previous and on-going activities. 52 representatives within CAMbrella nominated 43 key international stakeholders (individuals and organisations) and 15 of these were prioritised. Information from policy documents including mission statements, R&D strategies and R&D activities were collected in combination with personal interviews. Data were analysed using the principles of content analysis. Key stakeholders vary greatly in terms of capacity, mission and funding source (private/public). They ranged from only providing research funding to having a comprehensive R&D and communication agenda. A common shift in R&D strategy was noted; whereas 10 years ago research focused mainly on exploring efficacy and mechanisms, today the majority of stakeholders emphasise the importance of a broad spectrum of research, including methodologies exploring context, safety and comparative effectiveness. The scarce public investment in this field in Europe stands in stark contrast to the large investments found in Australia, Asia and North America. There is an emerging global trend supporting a broad research repertoire, including qualitative and comparative effectiveness research. This trend should be considered by the EU given the experience and the substantial research funding committed by the included stakeholders. To facilitate international collaborative efforts and minimise the risk of investment failure, we recommend the formation of a centralised EU CAM research centre fostering a broad CAM R&D agenda with the responsibility for implementing the relevant findings of CAMbrella.

  4. A common sense approach to nursing research.

    Science.gov (United States)

    Styles, M M

    1990-01-01

    Two events conspired to force me to develop and then articulate a political or power perspective on nursing research. During my term as president of the American Nurses' Association (ANA) experience taught me that knowledge is the currency of politics--politics defined broadly as governance by the institution, by the profession, by the industry or by the Congress. Data describe. Data explain. Data persuade. And, where the mind is made up, data justify. The second event was the June 1988 meeting in Jerusalem of the Workshop of European Nurse Researchers (WERN) where I was invited to speak on The Power of Knowledge: The Knowledge of Power. This was the challenge to put into words what I had learned on this subject throughout a career as academician topped with a tour in professional politics. The result is a common sense approach to nursing research that I would like to present to the nursing community for further debate.

  5. Approaches to establish Q-markers for the quality standards of traditional Chinese medicines.

    Science.gov (United States)

    Yang, Wenzhi; Zhang, Yibei; Wu, Wanying; Huang, Luqi; Guo, Dean; Liu, Changxiao

    2017-07-01

    Traditional Chinese medicine (TCM) has played a pivotal role in maintaining the health of Chinese people and is now gaining increasing acceptance around the global scope. However, TCM is confronting more and more concerns with respect to its quality. The intrinsic "multicomponent and multitarget" feature of TCM necessitates the establishment of a unique quality and bioactivity evaluation system, which is different from that of the Western medicine. However, TCM is investigated essentially as "herbal medicine" or "natural product", and the pharmacopoeia quality monographs are actually chemical-markers-based, which can ensure the consistency only in the assigned chemical markers, but, to some extent, have deviated from the basic TCM theory. A concept of "quality marker" (Q-marker), following the "property-effect-component" theory, is proposed. The establishment of Q-marker integrates multidisciplinary technologies like natural products chemistry, analytical chemistry, bionics, chemometrics, pharmacology, systems biology, and pharmacodynamics, etc. Q-marker-based fingerprint and multicomponent determination conduce to the construction of more scientific quality control system of TCM. This review delineates the background, definition, and properties of Q-marker, and the associated technologies applied for its establishment. Strategies and approaches for establishing Q-marker-based TCM quality control system are presented and highlighted with a few TCM examples.

  6. Mitigating global warming: traditional versus alternative approaches in a planning versus a market context

    Energy Technology Data Exchange (ETDEWEB)

    Olerup, Brita [Royal Inst. of Technology, Dept. of Industrial Economics and Management, Stockholm (Sweden)

    2002-06-01

    Economic efficiency tends to be an important argument when different means of environmental control are assessed and suggested. Considering that the most cost-efficient means are not the ones most frequently chosen and used, some other qualities seem to play an equally important role. I use findings from organisational theory and negotiation theory to better understand what is concealed in the black-box of decision-making and implementation. My empirical material consists of case studies of four different means of environmental control used in Sweden during the 1990s to mitigate the threat of global warming. These are an environmental tax, a licensing trial, municipal energy planning, and technology procurement. Each represents a particular discipline (economic, legal, physical planning, or technological) in which a context (planning or market) and an approach (traditional relay race or alternative process-oriented) are combined. Although each means has its particular niche, some qualities stand out as superior. Such means need to be divisible in space as well as in time. It is then easier to get started. Since it is just as easy to deviate from, rather than adhere to, the predetermined course after a while, some incentive must be given to the person in charge of implementation. In other words, the classic proverb of using sticks and carrots is still valid although it is not always taken to heart and practised. (Author)

  7. [Big data approaches in psychiatry: examples in depression research].

    Science.gov (United States)

    Bzdok, D; Karrer, T M; Habel, U; Schneider, F

    2017-11-29

    The exploration and therapy of depression is aggravated by heterogeneous etiological mechanisms and various comorbidities. With the growing trend towards big data in psychiatry, research and therapy can increasingly target the individual patient. This novel objective requires special methods of analysis. The possibilities and challenges of the application of big data approaches in depression are examined in closer detail. Examples are given to illustrate the possibilities of big data approaches in depression research. Modern machine learning methods are compared to traditional statistical methods in terms of their potential in applications to depression. Big data approaches are particularly suited to the analysis of detailed observational data, the prediction of single data points or several clinical variables and the identification of endophenotypes. A current challenge lies in the transfer of results into the clinical treatment of patients with depression. Big data approaches enable biological subtypes in depression to be identified and predictions in individual patients to be made. They have enormous potential for prevention, early diagnosis, treatment choice and prognosis of depression as well as for treatment development.

  8. Optimization of a Non-traditional Unsupervised Classification Approach for Land Cover Analysis

    Science.gov (United States)

    Boyd, R. K.; Brumfield, J. O.; Campbell, W. J.

    1982-01-01

    The conditions under which a hybrid of clustering and canonical analysis for image classification produce optimum results were analyzed. The approach involves generation of classes by clustering for input to canonical analysis. The importance of the number of clusters input and the effect of other parameters of the clustering algorithm (ISOCLS) were examined. The approach derives its final result by clustering the canonically transformed data. Therefore the importance of number of clusters requested in this final stage was also examined. The effect of these variables were studied in terms of the average separability (as measured by transformed divergence) of the final clusters, the transformation matrices resulting from different numbers of input classes, and the accuracy of the final classifications. The research was performed with LANDSAT MSS data over the Hazleton/Berwick Pennsylvania area. Final classifications were compared pixel by pixel with an existing geographic information system to provide an indication of their accuracy.

  9. Evaluation of a 'virtual' approach to commissioning health research.

    Science.gov (United States)

    McCourt, Christine A; Morgan, Philip A; Youll, Penny

    2006-10-18

    The objective of this study was to evaluate the implementation of a 'virtual' (computer-mediated) approach to health research commissioning. This had been introduced experimentally in a DOH programme--the 'Health of Londoners Programme'--in order to assess whether is could enhance the accessibility, transparency and effectiveness of commissioning health research. The study described here was commissioned to evaluate this novel approach, addressing these key questions. A naturalistic-experimental approach was combined with principles of action research. The different commissioning groups within the programme were randomly allocated to either the traditional face-to-face mode or the novel 'virtual' mode. Mainly qualitative data were gathered including observation of all (virtual and face-to-face) commissioning meetings; semi-structured interviews with a purposive sample of participants (n = 32/66); structured questionnaires and interviews with lead researchers of early commissioned projects. All members of the commissioning groups were invited to participate in collaborative enquiry groups which participated actively in the analysis process. The virtual process functioned as intended, reaching timely and relatively transparent decisions that participants had confidence in. Despite the potential for greater access using a virtual approach, few differences were found in practice. Key advantages included physical access, a more flexible and extended time period for discussion, reflection and information gathering and a more transparent decision-making process. Key challenges were the reduction of social cues available in a computer-mediated medium that require novel ways of ensuring appropriate dialogue, feedback and interaction. However, in both modes, the process was influenced by a range of factors and was not technology driven. There is potential for using computer-mediated communication within the research commissioning process. This may enhance access

  10. Evaluation of a 'virtual' approach to commissioning health research

    Directory of Open Access Journals (Sweden)

    Morgan Philip A

    2006-10-01

    Full Text Available Abstract Background The objective of this study was to evaluate the implementation of a 'virtual' (computer-mediated approach to health research commissioning. This had been introduced experimentally in a DOH programme – the 'Health of Londoners Programme' – in order to assess whether is could enhance the accessibility, transparency and effectiveness of commissioning health research. The study described here was commissioned to evaluate this novel approach, addressing these key questions. Methods A naturalistic-experimental approach was combined with principles of action research. The different commissioning groups within the programme were randomly allocated to either the traditional face-to-face mode or the novel 'virtual' mode. Mainly qualitative data were gathered including observation of all (virtual and face-to-face commissioning meetings; semi-structured interviews with a purposive sample of participants (n = 32/66; structured questionnaires and interviews with lead researchers of early commissioned projects. All members of the commissioning groups were invited to participate in collaborative enquiry groups which participated actively in the analysis process. Results The virtual process functioned as intended, reaching timely and relatively transparent decisions that participants had confidence in. Despite the potential for greater access using a virtual approach, few differences were found in practice. Key advantages included physical access, a more flexible and extended time period for discussion, reflection and information gathering and a more transparent decision-making process. Key challenges were the reduction of social cues available in a computer-mediated medium that require novel ways of ensuring appropriate dialogue, feedback and interaction. However, in both modes, the process was influenced by a range of factors and was not technology driven. Conclusion There is potential for using computer-mediated communication within

  11. Discovery of Intermetallic Compounds from Traditional to Machine-Learning Approaches.

    Science.gov (United States)

    Oliynyk, Anton O; Mar, Arthur

    2018-01-16

    Intermetallic compounds are bestowed by diverse compositions, complex structures, and useful properties for many materials applications. How metallic elements react to form these compounds and what structures they adopt remain challenging questions that defy predictability. Traditional approaches offer some rational strategies to prepare specific classes of intermetallics, such as targeting members within a modular homologous series, manipulating building blocks to assemble new structures, and filling interstitial sites to create stuffed variants. Because these strategies rely on precedent, they cannot foresee surprising results, by definition. Exploratory synthesis, whether through systematic phase diagram investigations or serendipity, is still essential for expanding our knowledge base. Eventually, the relationships may become too complex for the pattern recognition skills to be reliably or practically performed by humans. Complementing these traditional approaches, new machine-learning approaches may be a viable alternative for materials discovery, not only among intermetallics but also more generally to other chemical compounds. In this Account, we survey our own efforts to discover new intermetallic compounds, encompassing gallides, germanides, phosphides, arsenides, and others. We apply various machine-learning methods (such as support vector machine and random forest algorithms) to confront two significant questions in solid state chemistry. First, what crystal structures are adopted by a compound given an arbitrary composition? Initial efforts have focused on binary equiatomic phases AB, ternary equiatomic phases ABC, and full Heusler phases AB 2 C. Our analysis emphasizes the use of real experimental data and places special value on confirming predictions through experiment. Chemical descriptors are carefully chosen through a rigorous procedure called cluster resolution feature selection. Predictions for crystal structures are quantified by evaluating

  12. Translational research in behavior analysis: historical traditions and imperative for the future.

    Science.gov (United States)

    Mace, F Charles; Critchfield, Thomas S

    2010-05-01

    "Pure basic" science can become detached from the natural world that it is supposed to explain. "Pure applied" work can become detached from fundamental processes that shape the world it is supposed to improve. Neither demands the intellectual support of a broad scholarly community or the material support of society. Translational research can do better by seeking innovation in theory or practice through the synthesis of basic and applied questions, literatures, and methods. Although translational thinking has always occurred in behavior analysis, progress often has been constrained by a functional separation of basic and applied communities. A review of translational traditions in behavior analysis suggests that innovation is most likely when individuals with basic and applied expertise collaborate. Such innovation may have to accelerate for behavior analysis to be taken seriously as a general-purpose science of behavior. We discuss the need for better coordination between the basic and applied sectors, and argue that such coordination compromises neither while benefiting both.

  13. Assessing Pictograph Recognition: A Comparison of Crowdsourcing and Traditional Survey Approaches.

    Science.gov (United States)

    Kuang, Jinqiu; Argo, Lauren; Stoddard, Greg; Bray, Bruce E; Zeng-Treitler, Qing

    2015-12-17

    Compared to traditional methods of participant recruitment, online crowdsourcing platforms provide a fast and low-cost alternative. Amazon Mechanical Turk (MTurk) is a large and well-known crowdsourcing service. It has developed into the leading platform for crowdsourcing recruitment. To explore the application of online crowdsourcing for health informatics research, specifically the testing of medical pictographs. A set of pictographs created for cardiovascular hospital discharge instructions was tested for recognition. This set of illustrations (n=486) was first tested through an in-person survey in a hospital setting (n=150) and then using online MTurk participants (n=150). We analyzed these survey results to determine their comparability. Both the demographics and the pictograph recognition rates of online participants were different from those of the in-person participants. In the multivariable linear regression model comparing the 2 groups, the MTurk group scored significantly higher than the hospital sample after adjusting for potential demographic characteristics (adjusted mean difference 0.18, 95% CI 0.08-0.28, Ptraditional in-person surveys, but it cannot replace them.

  14. A Modern Approach to the Traditional Textbook: Bringing Introductory Geology Courses into the 21st Century

    Science.gov (United States)

    Workman Ford, K.; Ford, K. R.

    2013-12-01

    Undergraduate introductory geology courses are required in many colleges nationwide as part of the general education requirement. As a result, a large portion of those students are non-majors and most are not science majors. Textbooks used in these courses are often extensive with respect to the amount of material covered which tends to be overwhelming to the average student. Thus, students often purchase the pricey textbook but turn to their smartphones, notebooks, and laptops for answers. Before the development of the internet, students spent many hours in libraries and with their textbooks organizing and retrieving information. However, new technologies in the 21st century have essentially replaced traditional textbooks with students turning to online search engines, such as Google, to study and to complete homework assignments. Presently, online search engines may be more intuitive, but what's going on in the background isn't intuitive at all, and few students have a clear understanding of how search engines operate. Effectively this leads to students without the conception of how to build an adequate search strategy independent of search engines. Often, students are directed to online encyclopedias that may have erroneous information. Here, we employ an alternative to traditional textbooks and online search engines by implementing a guidebook with electronic resources for online activities and homework assignments. The proposed guidebook is roughly modeled after the American Geosciences Institute's Geoscience Handbook: AGI Data Sheets 4th, revised edition, and will include diagrams, graphs, charts, and pictures of basic geologic principles, processes, and earth materials. Along with the information, each topic will have online resources including sites for general reading, specific assignments that require visiting scientifically sound websites (i.e., USGS, GSA, AGU, Science, Nature), online self-assessment activities, and Google Earth activities. In addition

  15. Influence of Social Media on the Dissemination of a Traditional Surgical Research Article.

    Science.gov (United States)

    Buckarma, EeeLN H; Thiels, Cornelius A; Gas, Becca L; Cabrera, Daniel; Bingener-Casey, Juliane; Farley, David R

    Many institutions use social media to share research with the general public. However, the influence of social media on the dissemination of a surgical research article itself is unknown. Our objective was to determine whether a blog post highlighting the findings of a surgical research article would lead to increased dissemination of the article itself. We prospectively followed the online page views of an article that was published online in Surgery in May 2015 and published in print in August 2015. The authors subsequently released a blog post in October 2015 to promote the research. The number of article page views from the journal's website was obtained before and after the blog post, along with the page views from the blog post itself. Social media influence data were collected, including social activity in the form of mentions on social media sites, scholarly activity in online libraries, and scholarly commentary. The article's online activity peaked in the first month after online publication (475 page views). Online activity plateaued by 4 months after publication, with 118 monthly page views, and a blog post was subsequently published. The blog post was viewed by 1566 readers, and readers spent a mean of 2.5 minutes on the page. When compared to the projected trend, the page views increased by 33% in the month after the blog post. The blog post resulted in a 9% increase in the social media influence score and a 5% absolute increase in total article page views. Social media is an important tool for sharing surgical research. Our data suggest that social media can increase distribution of an article's message and also potentially increase dissemination of the article itself. We believe that authors should consider using social media to increase the dissemination of traditionally published articles. Copyright © 2016 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  16. Investigation of Liver Injury of Polygonum multiflorum Thunb. in Rats by Metabolomics and Traditional Approaches

    Directory of Open Access Journals (Sweden)

    Yun-Xia Li

    2017-11-01

    Full Text Available Liver injury induced by Polygonum multiflorum Thunb. (PM have been reported since 2006, which aroused widespread concern. However, the toxicity mechanism of PM liver injury remained unclear. In this study, the mechanism of liver injury induced by different doses of PM after long-term administration was investigated in rats by metabolomics and traditional approaches. Rats were randomly divided into control group and PM groups. PM groups were oral administered PM of low (10 g/kg, medium (20 g/kg, high (40 g/kg dose, while control group was administered distilled water. After 28 days of continuous administration, the serum biochemical indexes in the control and three PM groups were measured and the liver histopathology were analyzed. Also, UPLC-Q-TOF-MS with untargeted metabolomics was performed to identify the possible metabolites and pathway of liver injury caused by PM. Compared with the control group, the serum levels of ALT, AST, ALP, TG, and TBA in middle and high dose PM groups were significantly increased. And the serum contents of T-Bil, D-Bil, TC, TP were significantly decreased. However, there was no significant difference between the low dose group of PM and the control group except serum AST, TG, T-Bil, and D-Bil. Nine biomarkers were identified based on biomarkers analysis. And the pathway analysis indicated that fat metabolism, amino acid metabolism and bile acid metabolism were involved in PM liver injury. Based on the biomarker pathway analysis, PM changed the lipid metabolism, amino acid metabolism and bile acid metabolism and excretion in a dose-dependent manner which was related to the mechanism of liver injury.

  17. Human dissection: an approach to interweaving the traditional and humanistic goals of medical education.

    Science.gov (United States)

    Rizzolo, Lawrence J

    2002-12-15

    Anatomy remains one of the core courses of medical school, but the time devoted to it is decreasing. To accommodate the explosion of medical knowledge, educators search to streamline the curriculum. Because it is time-consuming, dissection comes under increased scrutiny. Even in the face of these pressures to reduce course hours, I would like to propose broadening, not reducing, the responsibilities of the anatomy instructor. Anatomy instructors can play a crucial role in helping medical schools meet the critical need to cultivate humanistic values, especially in the arena of end-of-life care. Anatomy can--and should--play an important role in a curriculum-wide effort to address this issue. Just as dissection remains an essential technique to teach three-dimensional concepts, the cadaver dissection lab is an ideal place to introduce concepts of humanistic care. The lab evokes the students' memories, speculations, and fears about serious illness in themselves, their families, and loved ones. Some programs address these reactions with supplemental activities, such as journaling, essay writing, and small group discussion. Valuable as these activities may be, anatomy instructors can achieve more by recognizing their role as a mentor, who can integrate humanistic values into traditional course objectives in a way that adds little time to the curriculum. The attitude of the instructor in ministering to the students' needs as they undertake the emotionally charged task of dissection can provide a model for how the students will respond, in turn, to the hopes and fears of their patients-and to their own reactions to dying. This approach will allow students to implement and practice humanistic values immediately, laying a foundation for their clinical training. Copyright 2002 Wiley-Liss, Inc.

  18. Decolonizing Qualitative Research: Non-traditional Reporting Forms in the Academy

    Directory of Open Access Journals (Sweden)

    Elsa M. González y González

    2006-09-01

    Full Text Available Qualitative researchers have assumed that cross-cultural work required deep understanding of the culture being reported on. Even earlier, cross-cultural work focused on "receiving contexts," and on end-users who were primarily Western. The utility of such studies is severely limited, however, in a globalized world, and studies undertaken now must serve the interests of not only Western scholars, but also the needs of nationals and locals (or indigenous peoples. Research conducted in different languages, non-Western contexts and different cultures becomes more problematic and understanding intrinsic issues more urgent with the increasing number of reports (such as dissertations conducted by international scholars and thus bear potential for decolonizing the academy. Conducting and reporting cross-cultural qualitative data focuses on understanding at least five major ideas: working with bilingual data, considering non-Western cultural traditions, multiple perspectives, multi-vocal & multi-lingual texts, and technical issues to insure accessibility. URN: urn:nbn:de:0114-fqs060418

  19. Mapping the Iranian Research Literature in the Field of Traditional Medicine in Scopus Database 2010-2014.

    Science.gov (United States)

    GhaedAmini, Hossein; Okhovati, Maryam; Zare, Morteza; Saghafi, Zahra; Bazrafshan, Azam; GhaedAmini, Alireza; GhaedAmini, Mohammadreza

    2016-05-01

    The aim of this study was to provide research and collaboration overview of Iranian research efforts in the field of traditional medicine during 2010-2014. This is a bibliometric study using the Scopus database as data source, using search affiliation address relevant to traditional medicine and Iran as the search strategy. Subject and geographical overlay maps were also applied to visualize the network activities of the Iranian authors. Highly cited articles (citations >10) were further explored to highlight the impact of research domains more specifically. About 3,683 articles were published by Iranian authors in Scopus database. The compound annual growth rate of Iranian publications was 0.14% during 2010-2014. Tehran University of Medical Sciences (932 articles), Shiraz University of Medical Sciences (404 articles) and Tabriz Islamic Medical University (391 articles), were the leading institutions in the field of traditional medicine. Medicinal plants (72%), digestive system's disease (21%), basics of traditional medicine (13%), mental disorders (8%) were the major research topics. United States (7%), Netherlands (3%), and Canada (2.6%) were the most important collaborators of Iranian authors. Iranian research efforts in the field of traditional medicine have been increased slightly over the last years. Yet, joint multi-disciplinary collaborations are needed to cover inadequately described areas of traditional medicine in the country.

  20. Comparing Hybrid Learning with Traditional Approaches on Learning the Microsoft Office Power Point 2003 Program in Tertiary Education

    Science.gov (United States)

    Vernadakis, Nikolaos; Antoniou, Panagiotis; Giannousi, Maria; Zetou, Eleni; Kioumourtzoglou, Efthimis

    2011-01-01

    The purpose of this study was to determine the effectiveness of a hybrid learning approach to deliver a computer science course concerning the Microsoft office PowerPoint 2003 program in comparison to delivering the same course content in the form of traditional lectures. A hundred and seventy-two first year university students were randomly…

  1. Evaluating Views of Lecturers on the Consistency of Teaching Content with Teaching Approach: Traditional versus Reform Calculus

    Science.gov (United States)

    Sevimli, Eyup

    2016-01-01

    This study aims to evaluate the consistency of teaching content with teaching approaches in calculus on the basis of lecturers' views. In this sense, the structures of the examples given in two commonly used calculus textbooks, both in traditional and reform classrooms, are compared. The content analysis findings show that the examples in both…

  2. On Chalk and Cheese, Babies and Bathwater and Squared Circles: Can Traditional and Communicative Approaches Be Reconciled?

    Science.gov (United States)

    Maley, Alan

    Many second language teachers in the People's Republic of China, upon encountering the communicative approach, reject it as both unworkable and unnecessary in China, where traditional instruction produces the expected results. However, the educational system is such that students who get to the university are highly motivated and talented, but the…

  3. Actual versus Implied Physics Students: How Students from Traditional Physics Classrooms Related to an Innovative Approach to Quantum Physics

    Science.gov (United States)

    Bøe, Maria Vetleseter; Henriksen, Ellen Karoline; Angell, Carl

    2018-01-01

    Calls for renewal of physics education include more varied learning activities and increased focus on qualitative understanding and history and philosophy of science (HPS) aspects. We have studied an innovative approach implementing such features in quantum physics in traditional upper secondary physics classrooms in Norway. Data consists of 11…

  4. Sociotechnical approaches to workplace safety: Research needs and opportunities

    Science.gov (United States)

    Robertson, Michelle M.; Hettinger, Lawrence J.; Waterson, Patrick E.; Ian Noy, Y.; Dainoff, Marvin J.; Leveson, Nancy G.; Carayon, Pascale; Courtney, Theodore K.

    2015-01-01

    The sociotechnical systems perspective offers intriguing and potentially valuable insights into problems associated with workplace safety. While formal sociotechnical systems thinking originated in the 1950s, its application to the analysis and design of sustainable, safe working environments has not been fully developed. To that end, a Hopkinton Conference was organised to review and summarise the state of knowledge in the area and to identify research priorities. A group of 26 international experts produced collaborative articles for this special issue of Ergonomics, and each focused on examining a key conceptual, methodological and/or theoretical issue associated with sociotechnical systems and safety. In this concluding paper, we describe the major conference themes and recommendations. These are organised into six topic areas: (1) Concepts, definitions and frameworks, (2) defining research methodologies, (3) modelling and simulation, (4) communications and decision-making, (5) sociotechnical attributes of safe and unsafe systems and (6) potential future research directions for sociotechnical systems research. Practitioner Summary: Sociotechnical complexity, a characteristic of many contemporary work environments, presents potential safety risks that traditional approaches to workplace safety may not adequately address. In this paper, we summarise the investigations of a group of international researchers into questions associated with the application of sociotechnical systems thinking to improve worker safety. PMID:25728246

  5. The Interpretative Phenomenological Analysis (IPA: A Guide to a Good Qualitative Research Approach

    Directory of Open Access Journals (Sweden)

    Abayomi Alase

    2017-04-01

    Full Text Available As a research methodology, qualitative research method infuses an added advantage to the exploratory capability that researchers need to explore and investigate their research studies. Qualitative methodology allows researchers to advance and apply their interpersonal and subjectivity skills to their research exploratory processes. However, in a study with an interpretative phenomenological analysis (IPA approach, the advantageous elements of the study quadruple because of the bonding relationship that the approach allows for the researchers to develop with their research participants. Furthermore, as a qualitative research approach, IPA gives researchers the best opportunity to understand the innermost deliberation of the ‘lived experiences’ of research participants. As an approach that is ‘participant-oriented’, interpretative phenomenological analysis approach allows the interviewees (research participants to express themselves and their ‘lived experience’ stories the way they see fit without any distortion and/or prosecution. Therefore, utilizing the IPA approach in a qualitative research study reiterates the fact that its main objective and essence are to explore the ‘lived experiences’ of the research participants and allow them to narrate the research findings through their ‘lived experiences’. As such, this paper discusses the historical background of phenomenology as both a theory and a qualitative research approach, an approach that has transitioned into an interpretative analytical tradition. Furthermore, as a resource tool to novice qualitative researchers, this paper provides a step-by-step comprehensive guide to help prepare and equip researchers with ways to utilize and apply the IPA approach in their qualitative research studies.  More importantly, this paper also provides an advanced in-depth analysis and usability application for the IPA approach in a qualitatively conducted research study. As such, this

  6. [Research on medical speciality of traditional Chinese medicines using dot-immunoblotting method based on polyclonal antibody prepared from traditional Chinese medicines with hot/cold nature].

    Science.gov (United States)

    Wang, Houwei; Dou, Yanling; Tian, Jingzhen; Li, Feng; Wang, Shijun; Wang, Zhenguo

    2009-02-01

    To research on the substantial foundation of the medical speciality of Chinese traditional medicines from immunogenicity. Control antigen with hot nature was prepared from the mixture of the aqueous extracts of three Chinese traditional medicines with three typical hot nature of Alpinia officinarum, Cinnamomum cassia and Curculigo orchioides, while that with cold nature prepared with Rheum palmatum, Anemarrhena asphodeloides, Coptis chinensis, and polyclonal antibody was prepared by immunizing rabbit with control antigen. Dot blotting was performed between the polyclonal antibody of control antigen and the aqueous extracts of nine Chinese traditional medicines on a piece of PVDF membrane, and the blotting signals were analyzed by the software of Quantity One. Blotting signals with hot control antigen of nine Chinese traditional medicines in descending were Zingiber officinale, Aconitum carmichaeli, Eucommia ulmoides, Fraxinus rhynchophylla, Lonicera japonica, Anemarrhena asphodeloides, Coptis chinensis, Rheum palmatum and Phellodendron chinense, which degree of similarity to control antigen in peak value were 57.33%, 43.56 %, 34.16%, 30.2%, 28.81%, 26.53%, 21.68%, 17.62% and 14.85%, respectively. Blotting signals with cold control antigen were Rheum palmatum, Anemarrhena asphodeloides, Coptis chinensis, Phellodendron chinense, Zingiber officinale, Lonicera japonica, Fraxinus rhynchophylla, Eucommia ulmoides and Aconitum carmichaeli in descending, of which degree of similarity to cold control antigen in peak value were 55.22%, 54.23%, 46.72%, 34.08%, 30.3%, 24.48%, 24.33%, 20.35% and 15.17%, respectively. Results of cluster analysis with Wistar's method showed that nine medicines were classified into two groups, one group included Phellodendron chinense, Anemarrhena asphodeloides, Coptis chinensis, Rheum palmatum, another was Zingiber officinale, Aconitum carmichaeli, Eucommia ulmoides, Fraxinus rhynchophylla, Lonicera japonica. Blotting signals of nine medicines

  7. Molecular biology approaches in bioadhesion research

    Directory of Open Access Journals (Sweden)

    Marcelo Rodrigues

    2014-07-01

    Full Text Available The use of molecular biology tools in the field of bioadhesion is still in its infancy. For new research groups who are considering taking a molecular approach, the techniques presented here are essential to unravelling the sequence of a gene, its expression and its biological function. Here we provide an outline for addressing adhesion-related genes in diverse organisms. We show how to gradually narrow down the number of candidate transcripts that are involved in adhesion by (1 generating a transcriptome and a differentially expressed cDNA list enriched for adhesion-related transcripts, (2 setting up a BLAST search facility, (3 perform an in situ hybridization screen, and (4 functional analyses of selected genes by using RNA interference knock-down. Furthermore, latest developments in genome-editing are presented as new tools to study gene function. By using this iterative multi-technologies approach, the identification, isolation, expression and function of adhesion-related genes can be studied in most organisms. These tools will improve our understanding of the diversity of molecules used for adhesion in different organisms and these findings will help to develop innovative bio-inspired adhesives.

  8. Comparsion analysis of data mining models applied to clinical research in traditional Chinese medicine.

    Science.gov (United States)

    Zhao, Yufeng; Xie, Qi; He, Liyun; Liu, Baoyan; Li, Kun; Zhang, Xiang; Bai, Wenjing; Luo, Lin; Jing, Xianghong; Huo, Ruili

    2014-10-01

    To help researchers selecting appropriate data mining models to provide better evidence for the clinical practice of Traditional Chinese Medicine (TCM) diagnosis and therapy. Clinical issues based on data mining models were comprehensively summarized from four significant elements of the clinical studies: symptoms, symptom patterns, herbs, and efficacy. Existing problems were further generalized to determine the relevant factors of the performance of data mining models, e.g. data type, samples, parameters, variable labels. Combining these relevant factors, the TCM clinical data features were compared with regards to statistical characters and informatics properties. Data models were compared simultaneously from the view of applied conditions and suitable scopes. The main application problems were the inconsistent data type and the small samples for the used data mining models, which caused the inappropriate results, even the mistake results. These features, i.e. advantages, disadvantages, satisfied data types, tasks of data mining, and the TCM issues, were summarized and compared. By aiming at the special features of different data mining models, the clinical doctors could select the suitable data mining models to resolve the TCM problem.

  9. Alternative approaches to research in physical therapy: positivism and phenomenology.

    Science.gov (United States)

    Shepard, K F; Jensen, G M; Schmoll, B J; Hack, L M; Gwyer, J

    1993-02-01

    This article presents philosophical approaches to research in physical therapy. A comparison is made to demonstrate how the research purpose, research design, research methods, and research data differ when one approaches research from the philosophical perspective of positivism (predominantly quantitative) as compared with the philosophical perspective of phenomenology (predominantly qualitative). Differences between the two approaches are highlighted by examples from research articles published in Physical Therapy. The authors urge physical therapy researchers to become familiar with the tenets, rigor, and knowledge gained from the use of both approaches in order to increase their options in conducting research relevant to the practice of physical therapy.

  10. An Effective Approach to Violence Prevention: Traditional Martial Arts in Middle School.

    Science.gov (United States)

    Zivin, Gail; Hassan, Nimr R.; DePaula, Geraldine F.; Monti, Daniel A.; Harlan, Carmen; Hossain, Kashfia D.; Patterson, Ksai

    2001-01-01

    Replicated and extended the design and outcome measures of several small studies. In these studies, juveniles at high risk for violence and delinquency showed decreased violence and positive changes in psychological risk factors after being required to take a school-linked course in traditional martial arts. (Author)

  11. The Impact of Nintendo Wii to Physical Education Students' Balance Compared to the Traditional Approaches

    Science.gov (United States)

    Vernadakis, Nikolaos; Gioftsidou, Asimenia; Antoniou, Panagiotis; Ioannidis, Dionysis; Giannousi, Maria

    2012-01-01

    The purpose of this study was to determine whether there is a difference between an exergame-based and a traditional balance training program, in undergraduate Physical Education students. Thirty two third-year undergraduate students at the Democritus University of Thrace were randomly divided into two training program groups of 16 students each,…

  12. A Comparative Meta-Analysis of 5E and Traditional Approaches in Turkey

    Science.gov (United States)

    Anil, Özgür; Batdi, Veli

    2015-01-01

    The aim of this study is to compare the 5E learning model with traditional learning methods in terms of their effect on students' academic achievement, retention and attitude scores. In this context, the meta-analytic method known as the "analysis of analyses" was used and a review undertaken of the studies and theses (N = 14) executed…

  13. Factors Affecting Students' Satisfaction in Engineering Disciplines: Traditional vs. Blended Approaches

    Science.gov (United States)

    Martinez-Caro, Eva; Campuzano-Bolarin, Francisco

    2011-01-01

    In this paper a two-year field study was carried out to analyse how satisfaction differs across the traditional and blended learning methods. Altogether, 21 courses for graduate and postgraduate engineering students were evaluated. Several variables and their relationship with student satisfaction in the first year, with all courses delivered in…

  14. The tradition algorithm approach underestimates the prevalence of serodiagnosis of syphilis in HIV-infected individuals.

    Directory of Open Access Journals (Sweden)

    Bin Chen

    2017-07-01

    Full Text Available Currently, there are three algorithms for screening of syphilis: traditional algorithm, reverse algorithm and European Centre for Disease Prevention and Control (ECDC algorithm. To date, there is not a generally recognized diagnostic algorithm. When syphilis meets HIV, the situation is even more complex. To evaluate their screening performance and impact on the seroprevalence of syphilis in HIV-infected individuals, we conducted a cross-sectional study included 865 serum samples from HIV-infected patients in a tertiary hospital. Every sample (one per patient was tested with toluidine red unheated serum test (TRUST, T. pallidum particle agglutination assay (TPPA, and Treponema pallidum enzyme immunoassay (TP-EIA according to the manufacturer's instructions. The results of syphilis serological testing were interpreted following different algorithms respectively. We directly compared the traditional syphilis screening algorithm with the reverse syphilis screening algorithm in this unique population. The reverse algorithm achieved remarkable higher seroprevalence of syphilis than the traditional algorithm (24.9% vs. 14.2%, p < 0.0001. Compared to the reverse algorithm, the traditional algorithm also had a missed serodiagnosis rate of 42.8%. The total percentages of agreement and corresponding kappa values of tradition and ECDC algorithm compared with those of reverse algorithm were as follows: 89.4%,0.668; 99.8%, 0.994. There was a very good strength of agreement between the reverse and the ECDC algorithm. Our results supported the reverse (or ECDC algorithm in screening of syphilis in HIV-infected populations. In addition, our study demonstrated that screening of HIV-populations using different algorithms may result in a statistically different seroprevalence of syphilis.

  15. The tradition algorithm approach underestimates the prevalence of serodiagnosis of syphilis in HIV-infected individuals.

    Science.gov (United States)

    Chen, Bin; Peng, Xiuming; Xie, Tiansheng; Jin, Changzhong; Liu, Fumin; Wu, Nanping

    2017-07-01

    Currently, there are three algorithms for screening of syphilis: traditional algorithm, reverse algorithm and European Centre for Disease Prevention and Control (ECDC) algorithm. To date, there is not a generally recognized diagnostic algorithm. When syphilis meets HIV, the situation is even more complex. To evaluate their screening performance and impact on the seroprevalence of syphilis in HIV-infected individuals, we conducted a cross-sectional study included 865 serum samples from HIV-infected patients in a tertiary hospital. Every sample (one per patient) was tested with toluidine red unheated serum test (TRUST), T. pallidum particle agglutination assay (TPPA), and Treponema pallidum enzyme immunoassay (TP-EIA) according to the manufacturer's instructions. The results of syphilis serological testing were interpreted following different algorithms respectively. We directly compared the traditional syphilis screening algorithm with the reverse syphilis screening algorithm in this unique population. The reverse algorithm achieved remarkable higher seroprevalence of syphilis than the traditional algorithm (24.9% vs. 14.2%, p algorithm, the traditional algorithm also had a missed serodiagnosis rate of 42.8%. The total percentages of agreement and corresponding kappa values of tradition and ECDC algorithm compared with those of reverse algorithm were as follows: 89.4%,0.668; 99.8%, 0.994. There was a very good strength of agreement between the reverse and the ECDC algorithm. Our results supported the reverse (or ECDC) algorithm in screening of syphilis in HIV-infected populations. In addition, our study demonstrated that screening of HIV-populations using different algorithms may result in a statistically different seroprevalence of syphilis.

  16. Implementing a Tactical Approach through Action Research

    Science.gov (United States)

    Gubacs-Collins, Klara

    2007-01-01

    Background: Influenced by the original observations of Bunker and Thorpe, physical education theorists began to question the effectiveness of a traditional model for teaching games and have increasingly begun to believe that concentrating only on specific motor responses (techniques) fails to take into account the contextual nature of games. Games…

  17. Methodological approaches in the research of organizational culture

    Directory of Open Access Journals (Sweden)

    Janićijević Nebojša

    2011-01-01

    Full Text Available In the thirty-years-long research of organizational culture, two mutually opposed methodological approaches have emerged: objectivistic quantitative and subjectivistic-qualitative. These two approaches are based on opposite ontological and epistemological assumptions: they include different types of research, and use opposite, quantitative vs. qualitative, methods of research. Each of the methodological approaches has its advantages and disadvantages. For this reason a hybrid approach emerges as a legitimate choice in organizational culture research methodology. It combines elements of both subjectivistic and objectivistic methodological approaches, according to the goals, content, and context of the research and preferences of the researcher himself/herself. Since it is possible to combine the two principal methodological approaches in various ways, there are several possible hybrid methodologies in organizational culture research. After the review of objectivistic quantitative and subjectivistic-qualitative methodological approaches, one of possible hybrid approaches in the research of organizational culture is presented in this paper.

  18. Research on the localization method of protecting traditional village landscape: a case study on Tangyin

    Directory of Open Access Journals (Sweden)

    W. Li

    2015-08-01

    Full Text Available China has over 271 million villages and less than the number in ten years ago in which there are 363 million villages. New rural construction indeed do some good for common villages but still destroy hundreds and thousands traditional village which contain great cultural, science, artistic values. In addition, traditional villages can't meet the increasing needs in more convenient and comfortable living conditions. Increasing population also makes traditional villages out of control in construction. With the background of this, we have to set up in traditional village protection. This article put forward an idea in protection which make use of landscape localization to pursue the sustainable development and vernacular landscape protection. Tangyin Town is a famous trade center in history and left many cultural heritage, especially historical buildings. Take Tangyin as a case study to apply the localization method which could guide other similar villages to achieve same goals.

  19. 21st century natural product research and drug development and traditional medicines.

    Science.gov (United States)

    Ngo, Linh T; Okogun, Joseph I; Folk, William R

    2013-04-01

    Natural products and related structures are essential sources of new pharmaceuticals, because of the immense variety of functionally relevant secondary metabolites of microbial and plant species. Furthermore, the development of powerful analytical tools based upon genomics, proteomics, metabolomics, bioinformatics and other 21st century technologies are greatly expediting identification and characterization of these natural products. Here we discuss the synergistic and reciprocal benefits of linking these 'omics technologies with robust ethnobotanical and ethnomedical studies of traditional medicines, to provide critically needed improved medicines and treatments that are inexpensive, accessible, safe and reliable. However, careless application of modern technologies can challenge traditional knowledge and biodiversity that are the foundation of traditional medicines. To address such challenges while fulfilling the need for improved (and new) medicines, we encourage the development of Regional Centres of 'omics Technologies functionally linked with Regional Centres of Genetic Resources, especially in regions of the world where use of traditional medicines is prevalent and essential for health.

  20. LIS Practitioner-focused Research Trends Toward Open Access Journals, Academic-focused Research Toward Traditional Journals

    Directory of Open Access Journals (Sweden)

    Richard Hayman

    2018-03-01

    Full Text Available A Review of: Chang, Y-W. (2017. Comparative study of characteristics of authors between open access and non-open access journals in library and information science. Library & Information Science Research, 39(1, 8-15. http://dx.doi.org/10.1016/j.lisr.2017.01.002   Abstract  Objective – To examine the occupational characteristics and publication habits of library and information science (LIS authors regarding traditional journals and open access journals. Design – Content analysis. Setting – English language research articles published in open access (OA journals and non-open access (non-OA journals from 2008 to 2013 that are indexed in LIS databases. Subjects – The authorship characteristics for 3,472 peer-reviewed articles. Methods – This researcher identified 33 total journals meeting the inclusion criteria by using the LIS categories within 2012 Journal Citation Reports (JCR to find 13 appropriate non-OA journals, and within the Directory of Open Access Journals (DOAJ to identify 20 appropriate OA journals. They found 1,665 articles by 3,186 authors published in the non-OA journals, and another 1,807 articles by 3,446 authors within the OA journals. The researcher used author affiliation to determine article authors’ occupations using information included in the articles themselves or by looking for information on the Internet, and excluded articles when occupational information could not be located. Authors were categorized into four occupational categories: Librarians (practitioners, Academics (faculty and researchers, Students (graduate or undergraduate, and Others. Using these categories, the author identified 10 different types of collaborations for co-authored articles. Main Results – This research involves three primary research questions. The first examined the occupational differences between authors publishing in OA journals versus non-OA journals. Academics (faculty and researchers more commonly published in non

  1. Systems Pharmacology-Based Approach of Connecting Disease Genes in Genome-Wide Association Studies with Traditional Chinese Medicine.

    Science.gov (United States)

    Kim, Jihye; Yoo, Minjae; Shin, Jimin; Kim, Hyunmin; Kang, Jaewoo; Tan, Aik Choon

    2018-01-01

    Traditional Chinese medicine (TCM) originated in ancient China has been practiced over thousands of years for treating various symptoms and diseases. However, the molecular mechanisms of TCM in treating these diseases remain unknown. In this study, we employ a systems pharmacology-based approach for connecting GWAS diseases with TCM for potential drug repurposing and repositioning. We studied 102 TCM components and their target genes by analyzing microarray gene expression experiments. We constructed disease-gene networks from 2558 GWAS studies. We applied a systems pharmacology approach to prioritize disease-target genes. Using this bioinformatics approach, we analyzed 14,713 GWAS disease-TCM-target gene pairs and identified 115 disease-gene pairs with q value < 0.2. We validated several of these GWAS disease-TCM-target gene pairs with literature evidence, demonstrating that this computational approach could reveal novel indications for TCM. We also develop TCM-Disease web application to facilitate the traditional Chinese medicine drug repurposing efforts. Systems pharmacology is a promising approach for connecting GWAS diseases with TCM for potential drug repurposing and repositioning. The computational approaches described in this study could be easily expandable to other disease-gene network analysis.

  2. Microbiological Research on the Traditional Alcoholic Fermented Milk“Airag”in Mongolia

    OpenAIRE

    宮本, 拓

    2015-01-01

     Airag, a traditional fermented milk well loved by Mongolians, has been drunk habitually sinceancient times as a unique drink. It is produced from cow, mare and camel milk by a traditional method using indigenous starter cultures containing lactic acid bacteria, yeasts and other fermentative microorganisms. Spontaneously fermented milk products have for centuries been consumed for their therapeutic value in promoting health and well-being, especially among the pastoral communities in Mongolia...

  3. An integrated approach project for the revaluation of a traditional sourdough bread production chain

    OpenAIRE

    Piazza, C.; Giudici, P.; Corbellini, M.; Gianinetti, A.; Morcia, C.; Terzi, V.

    2008-01-01

    The influence of organic and conventional farming systems on the performance of a panel of old and modern Italian bread wheat varieties has been evaluated, with the aim to individuate an agronomic protocol suitable for the production of a sourdough bread traditionally prepared in a hill zone of Emilia-Romagna. The agronomic and technological characterisation of the wheat samples obtained in organic and conventional farming conditions has been done and the sensorial qualities of the sourdough ...

  4. Metagenomic approach reveals microbial diversity and predictive microbial metabolic pathways in Yucha, a traditional Li fermented food

    OpenAIRE

    Zhang, Jiachao; Wang, Xiaoru; Huo, Dongxue; Li, Wu; Hu, Qisong; Xu, Chuanbiao; Liu, Sixin; Li, Congfa

    2016-01-01

    Yucha is a typical traditional fermented food of the Li population in the Hainan province of China, and it is made up of cooked rice and fresh fish. In the present study, metagenomic approach and culture-dependent technology were applied to describe the diversity of microbiota and identify beneficial microbes in the Yucha. At the genus level, Lactobacillus was the most abundant genus (43.82% of the total reads), followed by Lactococcus, Enterococcus, Vibrio, Weissella, Pediococcus, Enterobact...

  5. 11. Traditional and Innovative Methods in Approaching Music Styles. Pedagogical Implications

    Directory of Open Access Journals (Sweden)

    Iaţeşen Loredana Viorica

    2016-03-01

    Full Text Available The approach to music styles entails an in-depth musicological analysis aimed at synthesizing numerous bibliographical sources belonging to different fields and directions of research. A chronological overview of studies (Jean Molino, Fait musical et sémiologie de la musique, 1975; Jean Jaques Nattiez, Quelques reflexions du style, 1993; R. J. Pascall, Style, in The New Grove Dictionary of Music and Musicians, 1994; Jean Jaques Nattiez, La musique de l’avenir, in Musique. Une Encyclopédie pour le XXI siècle, 2003; Mario Baroni, Stil şi mutaţii stilistice în tradiţia muzicală europeană, in Musique Une encyclopédie pour le XXI siècle, 2006 and of universal (Leonard Meyer, Explaining Music, 1973; Charles Rosen, Le style classique: Haydn. Mozart, Beethoven, 1978; Leonard B. Meyer, Style and Music. Theory, History and Ideology, 1989; and Romanian specialised literature (Cornel Ţăranu, Elemente de stilistică muzicală (sec. XX, 1981; Edgar Papu, Despre stiluri, 1986; Valentina Sandu-Dediu, Alegeri Atitudini Afecte, 2010; Vasile Iliuţ, O carte a stilurilor muzicale, 2011; Valentin Timaru, Stilistică muzicală, 2014 from the late 20th century and the beginning of the 21st century, reveal the different and, more often than not, contrasting views of historians, analysts, aestheticians, philosophers, scholars and educators, starting from the meaning of the very idea of style, to the reception of this phenomenon in contemporaneity. On these grounds, this study proposes a systematization of the most relevant landmarks in documentation to date, for the purpose of applying them from a didactic perspective.

  6. Traditional vs. Modern Approaches in Business English Teaching in the Economic Field

    OpenAIRE

    Adriana Teodorescu

    2013-01-01

    This paper aims to examine different techniques and approaches used in teaching and learning business English in the economic field. Besides applying the already well-known methods used in second language acquisition, we also tried to incorporate computer-mediated communication into the communicative approach. At all times, the choice of the methods and approaches used in teaching business English has focused on our students' needs in their vocation or job. We worked with two groups of studen...

  7. An experimental detrending approach to attributing change of pan evaporation in comparison with the traditional partial differential method

    Science.gov (United States)

    Wang, Tingting; Sun, Fubao; Xia, Jun; Liu, Wenbin; Sang, Yanfang

    2017-04-01

    In predicting how droughts and hydrological cycles would change in a warming climate, change of atmospheric evaporative demand measured by pan evaporation (Epan) is one crucial element to be understood. Over the last decade, the derived partial differential (PD) form of the PenPan equation is a prevailing attribution approach to attributing changes to Epan worldwide. However, the independency among climatic variables required by the PD approach cannot be met using long term observations. Here we designed a series of numerical experiments to attribute changes of Epan over China by detrending each climatic variable, i.e., an experimental detrending approach, to address the inter-correlation among climate variables, and made comparison with the traditional PD method. The results show that the detrending approach is superior not only to a complicate system with multi-variables and mixing algorithm like aerodynamic component (Ep,A) and Epan, but also to a simple case like radiative component (Ep,R), when compared with traditional PD method. The major reason for this is the strong and significant inter-correlation of input meteorological forcing. Very similar and fine attributing results have been achieved based on detrending approach and PD method after eliminating the inter-correlation of input through a randomize approach. The contribution of Rh and Ta in net radiation and thus Ep,R, which has been overlooked based on the PD method but successfully detected by detrending approach, provides some explanation to the comparing results. We adopted the control run from the detrending approach and applied it to made adjustment of PD method. Much improvement has been made and thus proven this adjustment an effective way in attributing changes to Epan. Hence, the detrending approach and the adjusted PD method are well recommended in attributing changes in hydrological models to better understand and predict water and energy cycle.

  8. Recasting a traditional laboratory practical as a "Design-your-own protocol" to teach a universal research skill.

    Science.gov (United States)

    Whitworth, David E

    2016-07-08

    Laboratory-based practical classes are a common feature of life science teaching, during which students learn how to perform experiments and generate/interpret data. Practical classes are typically instructional, concentrating on providing topic- and technique-specific skills, however to produce research-capable graduates it is also important to develop generic practical skills. To provide an opportunity for students to develop the skills needed to create bespoke protocols for experimental benchwork, a traditional practical was repurposed. Students were given a list of available resources and an experimental goal, and directed to create a bench protocol to achieve the aim (measuring the iron in hemoglobin). In a series of teaching events students received feedback from staff, and peers prototyped the protocols, before protocols were finally implemented. Graduates highlighted this exercise as one of the most important of their degrees, primarily because of the clear relevance of the skills acquired to professional practice. The exercise exemplifies a range of pedagogic principles, but arguably its most important innovation is that it repurposed a pre-existing practical. This had the benefits of automatically providing scaffolding to direct the students' thought processes, while retaining the advantages of a "discovery learning" exercise, and allowing facile adoption of the approach across the sector. © 2016 by The International Union of Biochemistry and Molecular Biology, 44(4):377-380, 2016. © 2016 The International Union of Biochemistry and Molecular Biology.

  9. A targetted intervention research on traditional healer perspectives of sexually transmitted illnesses in urban Zambia. Current research.

    Science.gov (United States)

    Masauso Nzima, M; Romano, K; Anyangwe, S; Wiseman, J; Macwan'gi, M; Kendall, C; Green, E C

    1996-07-01

    Interviews with 81 traditional healers from 4 Copperbelt towns in Zambia (Chililabombwe, Chingola, Luanshya, and Mufulira) investigated healers' understanding of, attitudes toward, and management of sexually transmitted diseases (STDs). In general, Zambian traditional healers had detailed constructs of the physiology and infective processes underlying syphilis, gonorrhea, chancroid, and AIDS. STDs were considered to be caused by "dirt" or contamination residing in sperm or vaginal fluids and were closely linked to violations of moral codes. Healers shared complex nosologies based on distinctions between symptoms of different STD pathologies that were more inclusive than biomedical categories. Although condom use was not promoted, healers understood the importance of preventing an infective agent from passing from one person to another. Except for AIDS, STDs were considered curable by expelling the dirt through purgatives or emetics. Modern medicine was perceived as treating only STD symptoms, not curing. Most traditional healers insisted that the infected partner bring the other partner for consultation or treatment was withheld. Since these findings identified some areas of compatibility between indigenous and biomedical models of STDs, the Traditional Medicine Unit of the Ministry of Health and the HIV/AIDS Prevention Project of the Morehouse School of Medicine (Lusaka) established a program in which traditional healers receive AIDS training and learn to counsel clients on safer sex behaviors. Follow-up entails monthly meetings between health professionals and traditional healers. Since program initiation in June 1994, 800 traditional healers and 70 health professionals have participated. Traditional healers now sell condoms to their clients through a social marketing program.

  10. An Inquiry-Based Approach of Traditional "Step-by-Step" Experiments

    Science.gov (United States)

    Szalay, L.; Tóth, Z.

    2016-01-01

    This is the start of a road map for the effective introduction of inquiry-based learning in chemistry. Advantages of inquiry-based approaches to the development of scientific literacy are widely discussed in the literature. However, unless chemistry educators take account of teachers' reservations and identified disadvantages such approaches will…

  11. String figures as mathematics? an anthropological approach to string figure-making in oral tradition societies

    CERN Document Server

    Vandendriessche, Eric

    2015-01-01

    This book addresses the mathematical rationality contained in the making of string figures. It does so by using interdisciplinary methods borrowed from anthropology, mathematics, history and philosophy of mathematics. The practice of string figure-making has long been carried out in many societies, and particularly in those of oral tradition. It consists in applying a succession of operations to a string (knotted into a loop), mostly using the fingers and sometimes the feet, the wrists or the mouth. This succession of operations is intended to generate a final figure. The book explores differ

  12. New approach to high-risk pregnancy begins far earlier than traditional programs.

    Science.gov (United States)

    2002-10-01

    Why? Because traditional programs that focus on women as soon as they become pregnant are not making any headway against the incidence of low and very low birth weight (LBW) babies. As a result, while more of these babies are surviving, a significant number have disabilities that will impact them for life while costing the health care system dearly. Experts at Emory University in Atlanta believe there must be a better way to curb the incidence of poor birth outcomes, and they are putting their theories to work in a new program focused on "interpregnancy" care.

  13. Bat Species Comparisons Based on External Morphology: A Test of Traditional versus Geometric Morphometric Approaches.

    Science.gov (United States)

    Schmieder, Daniela A; Benítez, Hugo A; Borissov, Ivailo M; Fruciano, Carmelo

    2015-01-01

    External morphology is commonly used to identify bats as well as to investigate flight and foraging behavior, typically relying on simple length and area measures or ratios. However, geometric morphometrics is increasingly used in the biological sciences to analyse variation in shape and discriminate among species and populations. Here we compare the ability of traditional versus geometric morphometric methods in discriminating between closely related bat species--in this case European horseshoe bats (Rhinolophidae, Chiroptera)--based on morphology of the wing, body and tail. In addition to comparing morphometric methods, we used geometric morphometrics to detect interspecies differences as shape changes. Geometric morphometrics yielded improved species discrimination relative to traditional methods. The predicted shape for the variation along the between group principal components revealed that the largest differences between species lay in the extent to which the wing reaches in the direction of the head. This strong trend in interspecific shape variation is associated with size, which we interpret as an evolutionary allometry pattern.

  14. Bat Species Comparisons Based on External Morphology: A Test of Traditional versus Geometric Morphometric Approaches.

    Directory of Open Access Journals (Sweden)

    Daniela A Schmieder

    Full Text Available External morphology is commonly used to identify bats as well as to investigate flight and foraging behavior, typically relying on simple length and area measures or ratios. However, geometric morphometrics is increasingly used in the biological sciences to analyse variation in shape and discriminate among species and populations. Here we compare the ability of traditional versus geometric morphometric methods in discriminating between closely related bat species--in this case European horseshoe bats (Rhinolophidae, Chiroptera--based on morphology of the wing, body and tail. In addition to comparing morphometric methods, we used geometric morphometrics to detect interspecies differences as shape changes. Geometric morphometrics yielded improved species discrimination relative to traditional methods. The predicted shape for the variation along the between group principal components revealed that the largest differences between species lay in the extent to which the wing reaches in the direction of the head. This strong trend in interspecific shape variation is associated with size, which we interpret as an evolutionary allometry pattern.

  15. Qualitative methods: a research approach worth considering

    African Journals Online (AJOL)

    Qualitative research forms part of the classical cycle of research. ... putting aside any preconceived ideas and “intuiting”- focusing on the ... that is, no new information is obtained. ... and communication with the scientific community are adhered.

  16. Reconciling scientific approaches for organic farming research

    NARCIS (Netherlands)

    Baars, T.

    2002-01-01

    Part I : Reflection on research methods in organic grassland and animal production at the Louis Bolk Institute, The Netherlands

    Key words: organic agriculture, anthroposophy, methodology, research strategy, experiential science,

  17. Reaching Urban Poor Hypertensive Patients: A Novel Model of Chronic Disease Care Versus a Traditional Fee-for-Service Approach.

    Science.gov (United States)

    Sanders, Jim; Guse, Clare E

    2016-08-09

    There is a significant disparity in hypertensive treatment rates between those with and without health insurance. If left untreated, hypertension leads to significant morbidity and mortality. The uninsured face numerous barriers to access chronic disease care. We developed the Community-based Chronic Disease Management (CCDM) clinics specifically for the uninsured with hypertension utilizing nurse-led teams, community-based locations, and evidence-based clinical protocols. All services, including laboratory and medications, are provided on-site and free of charge. In order to ascertain if the CCDM model of care was as effective as traditional models of care in achieving blood pressure goals, we compared CCDM clinics' hypertensive care outcomes with 2 traditional fee-for-service physician-led clinics. All the clinics are located near one another in poor urban neighborhoods of Milwaukee, Wisconsin. Patients seen at the CCDM clinics and at 1 of the 2 traditional clinics showed a statistically significant improvement in reaching blood pressure goal at 6 months (P fee-for-service clinics when compared with the CCDM clinics. The CCDM model of care is at least as effective in controlling hypertension as more traditional fee-for-service models caring for the same population. The CCDM model of care to treat hypertension may offer another approach for engaging the urban poor in chronic disease care. © The Author(s) 2016.

  18. Environmental futures research: experiences, approaches, and opportunities

    Science.gov (United States)

    David N., comp. Bengston

    2012-01-01

    These papers, presented in a special session at the International Symposium on Society and Resource Management in June 2011, explore the transdisciplinary field of futures research and its application to long-range environmental analysis, planning, and policy. Futures research began in the post-World War II era and has emerged as a mature research field. Although the...

  19. The Research Journey: A "Lonely Planet" Approach

    Science.gov (United States)

    Mackenzie, Noella M.; Ling, Lorraine M.

    2009-01-01

    In this article the authors discuss the impact of research on a neophyte researcher and the research supervisor. The methodology which is applied throughout this article is autoethnographic narrative. It represents retrospective reflection on the part of the authors and thus to some extent is about retrospective meaning making. It centres upon the…

  20. Methodological Approaches in the Research of Organizational Culture

    OpenAIRE

    Nebojša Janićijević

    2011-01-01

    In the thirty-years-long research of organizational culture, two mutually opposed methodological approaches have emerged: objectivistic quantitative and subjectivistic-qualitative. These two approaches are based on opposite ontological and epistemological assumptions: they include different types of research, and use opposite, quantitative vs. qualitative, methods of research. Each of the methodological approaches has its advantages and disadvantages. For this reason a hybrid approach e...

  1. Detection of consensuses and treatment principles of diabetic nephropathy in traditional Chinese medicine: A new approach

    Directory of Open Access Journals (Sweden)

    Xu Tong

    2015-10-01

    Conclusion: The results suggest that the community detection-based approach is useful and feasible for uncovering consensuses and treatment principles of DN treatment in TCM, and could be used to address other similar problems in TCM.

  2. [Overview of research projects funding in traditional Chinese medicine oncology field supported by National Natural Science Foundation of China].

    Science.gov (United States)

    Tang, Dong-Xin; Chen, Lian-Yu; Guo, Shu-Zhen; Han, Li-Wei; Zhang, Feng-Zhu

    2017-05-01

    In this paper, the funding situation of traditional Chinese medicine oncology research projects supported by National Natural Science Fund from 1986-2016 was reviewed. The characteristics of funded projects were summarized from funding amount, funding expenses, funding category, and the main research contents of projects, etc. At the same time, the main problems in the projects were analyzed in this paper, in order to provide reference for the relevant fund applicants. Copyright© by the Chinese Pharmaceutical Association.

  3. [Research on collaborative innovation in traditional Chinese medicine of China based on patent cooperation network].

    Science.gov (United States)

    Li, Bei; Chen, Xiang-dong

    2015-03-01

    In the situation of global completion, collaborative innovation is becoming increasingly important because its advantage in risk avoiding and innovation efficiency. In order to explore the model of collaborative innovation and its evolution in traditional Chinese medicine of China, the cooperation in traditional Chinese medicine patents of China from 1985 to 2013 has been analyzed by using the method of scientometrics and social network analysis. It is proved that, though the number of grated cooperative patents has increased sharply during the last thirty years, the degree of cooperation innovation in traditional Chinese medicine of China is still not high. Moreover, in spite of the individual subject' s leading role in the past domestic collaborative innovation in traditional Chinese medicine of China, the institutions have been more and more powerful and achieved great improvement. At last, core institutions, represented by universities have played an important role in the collaborative innovation of domestic institutions, because they are key links between many institutions and promote the transferring and diffusion of knowledge.

  4. The qualities of the Machiya : An architectural research of a traditional house in Japan

    NARCIS (Netherlands)

    Jurgenhake, B.

    2011-01-01

    The Machiya, a traditional wooden house in the city of Kyoto, were demolished by thousands up to the nineties because of the lack of modern comfort these houses offer. In the last twenty years the consciousness of cultural heritage has grown and the city realizes that these old houses must have had

  5. Traditional Lecture Versus an Activity Approach for Teaching Statistics: A Comparison of Outcomes

    OpenAIRE

    Loveland, Jennifer L.

    2014-01-01

    Many educational researchers have proposed teaching statistics with less lecture and more active learning methods. However, there are only a few comparative studies that have taught one section of statistics with lectures and one section with activity-based methods; of those studies, the results are contradictory. To address the need for more research on the actual effectiveness of active learning methods in introductory statistics, this research study was undertaken. An introductory, univ...

  6. Comparison of Student Performance in Video Game Format vs. Traditional Approach in Introductory Astronomy Classes

    Science.gov (United States)

    Barringer, Daniel; Kregenow, Julia M.; Palma, Christopher; Plummer, Julia

    2015-01-01

    In Spring of 2014, Penn State debuted an online Introductory Astronomy (AST 001) section that was designed as a video game. Previous studies have shown that well-designed games help learners to build accurate understanding of embedded concepts and processes and aid learner motivation, which strongly contributes to a student's willingness to learn. We start by presenting the learning gains as measured with the Test of Astronomy Standards (TOAST) from this new course design. We further compare the learning gains from the video game section with learning gains measured from more traditional online formats and in-person lecture sections of AST 001 taught at Penn State over the last five years to evaluate the extent to which this new medium for online Astronomy education supports student learning.

  7. Participatory conservation approaches for satoyama, the traditional forest and agricultural landscape of Japan.

    Science.gov (United States)

    Kobori, Hiromi; Primack, Richard B

    2003-06-01

    The traditional agricultural landscape of Japan, known as satoyama, consists of a mixture of forests, wet rice paddy fields, grasslands, and villages. This landscape supports a great diversity of plant and animal species, many of which are significant to the Japanese culture. The satoyama landscape is currently being rapidly converted to residential and industrial uses in Japan's expanding metropolitan areas, with the local loss of many species. Only 7% of the land in the Yokohama area remains as satoyama. City residents and older farmers have become key participants in programs to protect examples of satoyama. Many urban residents value the experience of participating in agricultural and conservation activities once they are made aware of the threat faced by the satoyama landscape. In one particularly successful program, conservation efforts and fund-raising are linked to "Totoro", an imaginary forest animal featured in a popular animated film.

  8. A new interdisciplinary approach to the study of the origins of traditional polyphony

    Directory of Open Access Journals (Sweden)

    Jordania Joseph

    2015-01-01

    Full Text Available The article discusses a new model of the origins of choral singing in the context of human evolutionary history. Hominid interaction with predators is seen as a crucial force in the evolution of human morphology and behaviour. Group singing and dancing, with body painting and the use of masks, are perceived as critical elements of the strategy to deter predators and to put hominids into an altered state of consciousness. In this state, humans do not feel fear and pain and are ready to sacrifice their lives for the common goal. This psychological condition is still important to many human group activities, particularly in religion and the military. The mosaic distribution of polyphonic traditions is discussed in the context of the origins of language and articulated speech.

  9. Complexity and interdisciplinary approaches to environmental research

    Science.gov (United States)

    Kammen, Daniel M.

    2013-03-01

    The launch of volume 8 of Environmental Research Letters (ERL) comes at a critical time in terms of innovations and exciting areas of science, but particularly in the areas linking environmental research and action. The most recent climate change Conference of the Parties meeting (COP), in Doha in December 2012, has now come and gone. As has been dissected in the press, very little was accomplished. Some will see this as a failure, as I do, and others will reasonably enough note that this meeting, the 18th such COP was1 never intended to be a milestone moment. The current plan, in fact, is for a 'post-Kyoto' international climate agreement to be adopted only at the COP20 summit in December 2015. As we lead up to COP20, and potentially other regional or national approaches to climate protection, innovations in science, innovations in policy tools, and political commitment must come together. The science of climate change only continues to get clearer and clearer, and bleaker [1]. Later this year the IPCC will release its Fifth Assessment Report, AR5. The draft versions are out for review now. ERL has published a number of papers on climate change science, mitigation and adaptation, but one area where the world needs a particular focus is on the nexus of science and action. A summary of the Intergovernmental Panel on Climate Change's findings from the first assessment report (FAR; 1990) to the latest report is presented in figure 1. This graphic is specifically not about the scientific record alone. What is most important about this figure is the juxtaposition of the language of science and the language of ... language. Figure 1. Figure 1. A superposition of the state of climate science in three key data sets, and the dates of the first, second, third and fourth assessment reports (FAR, SAR, TAR, and AR4, respectively) plotted as vertical lines. On the right are the key statements from each of these reports, along with the conclusion of the Special Report on

  10. Moving Beyond the Systems Approach in SCM and Logistics Research

    DEFF Research Database (Denmark)

    Nilsson, Fredrik; Gammelgaard, Britta

    2012-01-01

    Purpose – The purpose of this paper is to provide a paradigmatic reflection on theoretical approaches recently identified in logistics and supply chain management (SCM); namely complex adaptive systems and complexity thinking, and to compare it to the dominant approach in logistics and SCM research...... for research results. This paper provides both a framework for and an analysis of such reflection which contributes to the further development of SCM and logistics research. Future research is needed to empirically provide insights on how complexity approaches can advance the area of SCM and logistics......, namely the systems approach. By analyzing the basic assumptions of the three approaches, SCM and logistics researchers are guided in their choice of research approaches which increases their awareness of the consequences different approaches have on theory and practice. Design...

  11. Moving Beyond the Systems Approach in SCM and Logistics Research

    DEFF Research Database (Denmark)

    Nilsson, Fredrik; Gammelgaard, Britta

    2012-01-01

    Purpose – The purpose of this paper is to provide a paradigmatic reflection on theoretical approaches recently identified in logistics and supply chain management (SCM); namely complex adaptive systems and complexity thinking, and to compare it to the dominant approach in logistics and SCM research......, namely the systems approach. By analyzing the basic assumptions of the three approaches, SCM and logistics researchers are guided in their choice of research approaches which increases their awareness of the consequences different approaches have on theory and practice. Design...... to the dominant approach in SCM and logistics research, the systems approach, it is concluded that the underlying assumptions of complex adaptive systems and complexity thinking are more appropriate than systems approach for contemporary challenges of organizational complexity in SCM and logistics. It is found...

  12. From ancient to avant-garde: a review of traditional and modern multimodal approaches to surgical anatomy education.

    Science.gov (United States)

    Hu, Minhao; Wattchow, David; de Fontgalland, Dayan

    2018-03-01

    The landscape of surgical anatomy education is progressively changing. Traditional methods, such as cadaveric dissection and didacticism are being increasingly phased out in undergraduate courses for multimodal approaches incorporating problem-based learning, radiology and computer-based simulations. Although effective at clinically contextualizing and integrating anatomical information, these approaches may be a poor substitute for fostering a grasp of foundational 'pure' anatomy. Dissection is ideal for this purpose and hence remains the cornerstone of anatomical education. However, novel methods and technological advancements continually give way to adjuncts such as cadaveric surgery, three-dimensional printing, virtual simulation and live surgical streaming, which have demonstrated significant efficacy alone or alongside dissection. Therefore, although divergent paradigms of 'new versus old' approaches have engulfed and divided the community, educators should seek to integrate the ancient and avant-garde to comprehensively satisfy all of the modern anatomy learner's educational needs. © 2017 Royal Australasian College of Surgeons.

  13. Assessing approaches for dissemination of research information to ...

    African Journals Online (AJOL)

    Mo

    Assessing approaches for dissemination of research information to farmers within their ... to soil improvement, NAADS had a wide scope that included animal husbandry. Farmers .... the Problem Solving Approach that involves defining the approach ..... Assessing the Quality of Participation in Farmers' Research Groups.

  14. Traditional Indigenous Approaches to Healing and the modern welfare of Traditional Knowledge, Spirituality and Lands: A critical reflection on practices and policies taken from the Canadian Indigenous Example

    Directory of Open Access Journals (Sweden)

    Julian A. Robbins

    2011-10-01

    Full Text Available In order for traditional knowledge to be maintained and to develop, it has to be practiced. Traditional healing provides a vehicle for this to occur. In Canada, the spiritual revitalization of Indigenous communities and individuals often involves the use numerous components of traditional healing. These elements are reflectedmost clearly at the grassroots level, however, current Indigenous programs delivered by Indigenous and governmental agencies have made some accommodating efforts as well. Perhaps most importantly, traditional knowledge and Indigenous spirituality hinges on the maintenance and renewal of relationships to the land.Indigenous land bases and the environment as a whole remain vitally important to the practice of traditional healing.A focus on Indigenous healing, when discussing Indigenous knowledge systems and spirituality, is paramount today due to the large scale suppression of Indigenous cultural expressions during the process of colonization. With respect to policy, there appears to be a historical progression of perception or attitude towards Indigenous traditional healing in Canada from one of disfavour to one favour. There are nevertheless continuing challenges for traditional healing. Mainstream perceptions and subsequent policy implementations sometimes still reflect attitudes that were formulated during the decline of traditional healing practice during colonization processes. As a consequence the ability for particular communities to maintain and use their specific understandings ofIndigenous knowledge continues encounter obstacles. Indigenous Knowledge systems are living entities and not relics of the past. Today, these knowledge systems are still greatly being applied to help Indigenous communities and Indigenous people recover fromintergenerational pain and suffering endured during the colonization process. Future policy development and implementation should aim to support Indigenous peoples and communities when

  15. Barriers to Research Utilization among Registered Nurses in Traditional Chinese Medicine Hospitals: A Cross-Sectional Survey in China

    Directory of Open Access Journals (Sweden)

    Fen Zhou

    2015-01-01

    Full Text Available Background. As there might be relevant differences with regard to research utilization in the general hospitals, we aimed to study research utilization among registered nurses working in traditional Chinese medicine hospitals. Methods. A total of 648 registered nurses from 4 tertiary-level hospitals in China were recruited for participation. A modified BARRIERS Scale and self-designed questionnaires were used for data collection. Data were analyzed with descriptive statistics, t-tests, and one-way ANOVAs and Spearman correlation analysis. Results. Overall, items which belong to the subscale “Research” were identified as the most important barriers. Among the individual items, the lack of time on the job was ranked as the top barrier, followed by the lack of knowledgeable colleagues and by overwhelming research publications. Clinical experience, working pressure, job satisfaction, and research experience could be identified as associated factors for barriers to research utilization. Conclusions. Registered nurses in traditional Chinese medicine hospitals felt high barriers to research utilization. Reducing registered nurses’ working pressure, promoting their positive attitude to nursing, and improving research training might be helpful for increasing research utilization. Close cooperation between clinical and nursing schools or academic research centres might facilitate the necessary change in nursing education and routine.

  16. A Novel Interactive Online Module in a Traditional Curriculum through a Blended Learning Approach

    Science.gov (United States)

    Gibbard, Leslie Laing; Salajan, Florin

    2009-01-01

    A unique approach was planned and implemented for undergraduate dental students that would reinforce the principles of removable partial denture (RPD) design. 162 students were grouped according to their year of dental studies (66 second-year students and 96 third-year students) within the Discipline of Prosthodontics at the Faculty of Dentistry,…

  17. Modern versus Tradition: Are There Two Different Approaches to Reading of the Confucian Classics?

    Science.gov (United States)

    Cheng, Chung-yi

    2016-01-01

    How to read the Confucian Classics today? Scholars with philosophical training usually emphasize that the philosophical approach, in comparison with the classicist and historical ones, is the best way to read the Confucian Classics, for it can dig out as much intellectual resources as possible from the classical texts in order to show their modern…

  18. Origins of Life Research: a Bibliometric Approach

    Science.gov (United States)

    Aydinoglu, Arsev Umur; Taşkın, Zehra

    2018-03-01

    This study explores the collaborative nature and interdisciplinarity of the origin(s) of life (OoL) research community. Although OoL research is one of the oldest topics in philosophy, religion, and science; to date there has been no review of the field utilizing bibliometric measures. A dataset of 5647 publications that are tagged as OoL, astrobiology, exobiology, and prebiotic chemistry is analyzed. The most prolific authors (Raulin, Ehrenfreund, McKay, Cleaves, Cockell, Lazcano, etc.), most cited scholars and their articles (Miller 1953, Gilbert 1986, Chyba & Sagan 1992, Wolchtershauser 1988, etc.), and popular journals ( Origins of Life and Evolution of Biospheres and Astrobiology) for OoL research are identified. Moreover, interdisciplinary research conducted through research networks, institutions (NASA, Caltech, University of Arizona, University of Washington, CNRS, etc.), and keywords & concepts (astrobiology, life, Mars, amino acid, prebiotic chemistry, evolution, RNA) are explored.

  19. [Current topics on cancer biology and research strategies for anti-cancer traditional Chinese medicine].

    Science.gov (United States)

    Chen, Xiu-ping; Tang, Zheng-hai; Shi, Zhe; Lu, Jin-jian; Su, Huan-xing; Chen, Xin; Wang, Yi-tao

    2015-09-01

    Cancer, an abnormal cell proliferation resulted from multi-factors,has the highest morbidity and mortality among all the serious diseases. Considerable progress has been made in cancer biology in recent years. Tumor immunology, cancer stem cells (CSCs), autophagy, and epithelial-mesenchymal transition (EMT) have become hot topics of interests in this area. Detailed dissection of these biological processes will provide novel directions, targets, and strategies for the pharmacological evaluation, mechanism elucidation, and new drug development of traditional Chinese medicine.

  20. Researching health inequalities with Community Researchers: practical, methodological and ethical challenges of an 'inclusive' research approach.

    Science.gov (United States)

    Salway, Sarah; Chowbey, Punita; Such, Elizabeth; Ferguson, Beverly

    2015-01-01

    Public health research sometimes uses members of communities as researchers. These are called Community Researchers. The advantage of using Community Researchers is that it enables people who live in communities to participate in research by designing the research, gathering data and being involved in analysis. This 'participatory' approach also has the potential to reach communities that might otherwise not be included in research. There are few studies that report the experiences of Community Researchers who take part in such research. This study helps fill this gap by exploring the issues and challenges faced by Community Researchers involved in a study of health and poverty in ethnically mixed areas of east London, UK. Through the accounts of 12 researchers, the study reveals that being a community 'insider' had advantages: many felt they had been able to gain the trust of respondents and access people for the research that would have otherwise been missed. The role of Community Researcher was, however, difficult to manage with some researchers feeling burdened by their role and the increased knowledge they had about the lives of those in their community. In addition to the personal challenges for the Community Researchers, the findings raise various ethical and methodological issues that need consideration in participatory research. Background Inclusive research approaches are increasingly employed by public health researchers. Recent methodological development includes the engagement of Community Researchers (CRs), who use their knowledge and networks to facilitate research with the community with which they identify. Few studies have explored the experiences of CRs in the research process, an important element of any comprehensive assessment of the pros and cons of such research endeavours. We report here on the experiences of CRs engaged in a study of health inequalities and poverty in ethnically diverse and disadvantaged areas of London, UK. Methods We

  1. Case Studies Approach in Tourism Destination Branding Research

    OpenAIRE

    Adeyinka-Ojo S.F.; Nair V.; Khoo-Lattimore C.

    2014-01-01

    A review of literature indicates that there are different types of qualitative research methods such as action research, content analysis, ethnography, grounded theory, historical analysis, phenomenology and case study. However, which approach is to be used depends on several factors such as the nature and objectives of the research. The aim of this paper is to focus on the research methodology aspects of applying case study as a research approach and its relevance in tourism destination bran...

  2. Fish crackers development from minced fish and starch: an innovative approach to a traditional product

    Directory of Open Access Journals (Sweden)

    Cristiane Rodrigues Pinheiro Neiva

    2011-12-01

    Full Text Available This study aimed to develop sensory acceptable, high nutritional value fish crackers that could be kept at room temperature for 180 days. Minced fish of different low-value species was the raw material employed to produce two types of fish crackers: a the traditional keropok cracker, which was expanded by deep frying; and b a low-fat fish cracker, expanded by microwave cooking. The protein content of the fried fish crackers (FFCs and that of the microwaved fish crackers (MFCs were high (10.86 and 14.70%, respectively. The essential amino acid contents of the two types of fish cracker were above the FAO requirements for adults, and the lysine content was above the requirements for children. Sensory analysis, performed by adult panelists, resulted in a general level of acceptability of 90% for the MFCs and of 97% for the FFCs. Vacuum packaging maintained microbiological and physicochemical properties for a storage period of 180 days at room temperature.

  3. Virtual surgery simulation versus traditional approaches in training of residents in cervical pedicle screw placement.

    Science.gov (United States)

    Hou, Yang; Shi, Jiangang; Lin, Yanping; Chen, Huajiang; Yuan, Wen

    2018-06-01

    The cervical screw placement is one of the most difficult procedures in spine surgery, which often needs a long period of repeated practices and could cause screw placement-related complications. We performed this cadaver study to investigate the effectiveness of virtual surgical training system (VSTS) on cervical pedicle screw instrumentation for residents. A total of ten novice residents were randomly assigned to two groups: the simulation training (ST) group (n = 5) and control group (n = 5). The ST group received a surgical training of cervical pedicle screw placement on VSTS and the control group was given an introductory teaching session before cadaver test. Ten fresh adult spine specimens including 6 males and 4 females were collected, and were randomly allocated to the two groups. The bilateral C3-C6 pedicle screw instrumentation was performed in the specimens of the two groups, respectively. After instrumentation, screw positions of the two groups were evaluated by image examinations. There was significantly statistical difference in screw penetration rates between the ST (10%) and control group (62.5%, P VSTS as an advanced training tool exhibited promising effects on improving performance of novice residents in cervical pedicle screw placement compared with the traditional teaching methods.

  4. A HUMANISING ECONOMIC APPROACH ON COMPETITION POLICY OR HOW THE BEHAVIORAL ECONOMICS BLENDS WITH “TRADITIONAL ECONOMICS”

    Directory of Open Access Journals (Sweden)

    Liviana Andreea Niminet

    2015-07-01

    Full Text Available Behavioral are crucial for understanding both the consumer’s attitude and firms’ attitude as well as for understanding the market outcomes. The past ten years brought a lot of attention from researchers and policy-makers on the behavioral economics issue. Classical, traditional economic models rely on the assumptions of rationality and ordered preferences. Behavioral economics explores interactions between demand and supply including information framing, the use of heuristics in decision-making and time-inconsistent preferences. The research on behavioral economics has led to an extensive debate about the relative merits of both traditional and behavioral economics. First of all we propose to highlight the advantages and disadvantages of behavioral economics versus traditional economics on a very sensitive issue: the competition policy. Then we address market issues that can be solved by means of behavioral economics afterwards turning out attention to the remedies of behavioral economics and ,last but not least, the United Kingdom successful model on the matter of competition policy.

  5. Nuclear medical approaches to clinical research

    International Nuclear Information System (INIS)

    Otte, Andreas; Nguyen, Tristan

    2009-01-01

    In the frame of the master course Clinical research management at the scientific college Lahr in cooperation with the Albert-Ludwigs-University Freiburg three contributions are presented: Functional imaging - supported clinical studies in the sleep research. A comparison of NMR imaging versus SPECT and PET (advantages and disadvantages). Clinical studies with ionizing radiation and the radiation fear of the public. The new radioimmunotherapeutic agent Zevalin and the challenges at the market.

  6. Employing a Qualitative Description Approach in Health Care Research

    Science.gov (United States)

    Bradshaw, Carmel; Atkinson, Sandra; Doody, Owen

    2017-01-01

    A qualitative description design is particularly relevant where information is required directly from those experiencing the phenomenon under investigation and where time and resources are limited. Nurses and midwives often have clinical questions suitable to a qualitative approach but little time to develop an exhaustive comprehension of qualitative methodological approaches. Qualitative description research is sometimes considered a less sophisticated approach for epistemological reasons. Another challenge when considering qualitative description design is differentiating qualitative description from other qualitative approaches. This article provides a systematic and robust journey through the philosophical, ontological, and epistemological perspectives, which evidences the purpose of qualitative description research. Methods and rigor issues underpinning qualitative description research are also appraised to provide the researcher with a systematic approach to conduct research utilizing this approach. The key attributes and value of qualitative description research in the health care professions will be highlighted with the aim of extending its usage. PMID:29204457

  7. Employing a Qualitative Description Approach in Health Care Research.

    Science.gov (United States)

    Bradshaw, Carmel; Atkinson, Sandra; Doody, Owen

    2017-01-01

    A qualitative description design is particularly relevant where information is required directly from those experiencing the phenomenon under investigation and where time and resources are limited. Nurses and midwives often have clinical questions suitable to a qualitative approach but little time to develop an exhaustive comprehension of qualitative methodological approaches. Qualitative description research is sometimes considered a less sophisticated approach for epistemological reasons. Another challenge when considering qualitative description design is differentiating qualitative description from other qualitative approaches. This article provides a systematic and robust journey through the philosophical, ontological, and epistemological perspectives, which evidences the purpose of qualitative description research. Methods and rigor issues underpinning qualitative description research are also appraised to provide the researcher with a systematic approach to conduct research utilizing this approach. The key attributes and value of qualitative description research in the health care professions will be highlighted with the aim of extending its usage.

  8. Using a Guided Inquiry Approach in the Traditional Vertebrate Anatomy Laboratory

    Science.gov (United States)

    Meuler, Debra

    2008-01-01

    A central theme of the "National Science Education Standards" is teaching science as an inquiry process, allowing students to explore an authentic problem using the tools and skills of the discipline. Research indicates that more active participation by the student, which usually requires higher-order thinking skills, results in deeper learning.…

  9. Fluorescent Protein Approaches in Alpha Herpesvirus Research

    Directory of Open Access Journals (Sweden)

    Ian B. Hogue

    2015-11-01

    Full Text Available In the nearly two decades since the popularization of green fluorescent protein (GFP, fluorescent protein-based methodologies have revolutionized molecular and cell biology, allowing us to literally see biological processes as never before. Naturally, this revolution has extended to virology in general, and to the study of alpha herpesviruses in particular. In this review, we provide a compendium of reported fluorescent protein fusions to herpes simplex virus 1 (HSV-1 and pseudorabies virus (PRV structural proteins, discuss the underappreciated challenges of fluorescent protein-based approaches in the context of a replicating virus, and describe general strategies and best practices for creating new fluorescent fusions. We compare fluorescent protein methods to alternative approaches, and review two instructive examples of the caveats associated with fluorescent protein fusions, including describing several improved fluorescent capsid fusions in PRV. Finally, we present our future perspectives on the types of powerful experiments these tools now offer.

  10. Frame by frame stop motion non-traditional approaches to stop motion animation

    CERN Document Server

    Gasek, Tom

    2011-01-01

    In a world that is dominated by computer images, alternative stop motion techniques like pixilation, time-lapse photography and down-shooting techniques combined with new technologies offer a new, tangible and exciting approach to animation. With over 25 years professional experience, industry veteran, Tom Gasek presents a comprehensive guide to stop motion animation without the focus on puppetry or model animation. With tips, tricks and hands-on exercises, Frame by Frame will help both experienced and novice filmmakers get the most effective results from this underutilized branch of animation

  11. Maintaining research traditions on place: diversity of thought and scientific progress

    Science.gov (United States)

    Michael E. Patterson; Daniel R. Williams

    2005-01-01

    Since the 1990s, numerous authors have expressed concerns about lack of conceptual clarity in research on place. Some authors suggest that place research has failed to evolve into a systematic and coherent body of knowledge. We believe recent critiques do not adequately characterize the state of knowledge in place research, but responding to the issues raised requires...

  12. Gratitude in Workplace Research: A Rossian Approach

    Science.gov (United States)

    Gibbs, Paul

    2009-01-01

    Workplace learning is complex in form. It is explorative, social and creative enquiry, and because it is carried out in the socio-political domain of the workplace, it is potentially exploitative of all who contribute. This paper suggests that the workplace researcher might conceptualise the contributions of participants as benefits and/or gifts,…

  13. A dynamic discourse approach to classroom research

    NARCIS (Netherlands)

    Bannink, A.; Van Dam, J.

    2006-01-01

    In this paper we propose a theoretical reassessment of the discourse-analytic tools that are used in classroom research and of the data that are addressed. To that end we present in-depth analyses of 1) an IRE structure in a first English (EFL) lesson in a Dutch secondary school; 2) episodes from

  14. Comparative Study Between the Two Experimental Design Approaches Taguchi and Traditional in Presence of Control by Control Interactions

    Directory of Open Access Journals (Sweden)

    Arias-Nava Elías Heriberto

    2015-03-01

    Full Text Available Design of experiments plays an important role in the field of creating and innovating process and products directly in manufacturing and improving areas. There are several areas into designs of experiments; robust design is one of them. Robust parameter design is a principle that emphasize in products creation through a correct selection of values called “control” which make a product robust to the variability by the noise introducing by another factors known as “noise” factors. This article aims for a comparative study between two well-known robust design methodologies, making a special emphasis in the control by control interaction effects over optimal operating conditions. The results showed that Taguchi´s crossed arrays are unable to estimate all significant terms in a model. The optimizations result concludes that the Taguchi´s approach is less efficient than the traditional approach in both; maximization and minimization.

  15. Towards Principles-Based Approaches to Governance of Health-related Research using Personal Data.

    Science.gov (United States)

    Laurie, Graeme; Sethi, Nayha

    2013-01-01

    Technological advances in the quality, availability and linkage potential of health data for research make the need to develop robust and effective information governance mechanisms more pressing than ever before; they also lead us to question the utility of governance devices used hitherto such as consent and anonymisation. This article assesses and advocates a principles-based approach, contrasting this with traditional rule-based approaches, and proposes a model of principled proportionate governance . It is suggested that the approach not only serves as the basis for good governance in contemporary data linkage but also that it provides a platform to assess legal reforms such as the draft Data Protection Regulation.

  16. Towards Principles-Based Approaches to Governance of Health-related Research using Personal Data

    Science.gov (United States)

    Laurie, Graeme; Sethi, Nayha

    2013-01-01

    Technological advances in the quality, availability and linkage potential of health data for research make the need to develop robust and effective information governance mechanisms more pressing than ever before; they also lead us to question the utility of governance devices used hitherto such as consent and anonymisation. This article assesses and advocates a principles-based approach, contrasting this with traditional rule-based approaches, and proposes a model of principled proportionate governance. It is suggested that the approach not only serves as the basis for good governance in contemporary data linkage but also that it provides a platform to assess legal reforms such as the draft Data Protection Regulation. PMID:24416087

  17. Tackling perinatal loss, a participatory action research approach: research protocol.

    Science.gov (United States)

    Pastor-Montero, Sonia María; Romero-Sánchez, José Manuel; Paramio-Cuevas, Juan Carlos; Hueso-Montoro, César; Paloma-Castro, Olga; Lillo-Crespo, Manuel; Castro-Yuste, Cristina; Toledano-Losa, Ana Cristina; Carnicer-Fuentes, Concepción; Ortegón-Gallego, José Alejo; Frandsen, Anna J

    2012-11-01

      The aim of this study was to promote changes to improve the care provided to parents who have experienced a perinatal loss through participatory action research.   The birth of a child is a joyful event for most families, however, unfortunately some pregnancies end in loss. Perinatal loss creates a heavy emotional impact not only on parents but also on health professionals, where in most cases there is an evident lack of skills, strategies and resources to cope with these kinds of situations.   Participatory action research is the methodology proposed to achieve the purpose of this study.   Participatory action research consists of five stages: outreach and awareness, induction, interaction, implementation and systematization. The working group will include professionals from the Mother and Child Unit for patients at a tertiary level public hospital in Spain. The duration of the study will be 3 years since the approval of the protocol in January 2011. The qualitative techniques used will include group dynamics such as the SWOT analysis the nominal group technique, focus groups and brainstorming, among others that will be recorded and transcribed, generating reports throughout the evolution of the group sessions and about the consensus reached. Content analysis will be conducted on the field diaries kept by the participants and researchers. This project has been funded by the Andalusian Regional Ministry of Health.   Participatory action research is a methodological strategy that allows changes in clinical practice to conduct a comprehensive transformative action in the care process for perinatal loss. © 2012 Blackwell Publishing Ltd.

  18. A sequential mixed methods research approach to investigating HIV ...

    African Journals Online (AJOL)

    2016-09-03

    Sep 3, 2016 ... Sequential mixed methods research is an effective approach for ... show the effectiveness of the research method. ... qualitative data before quantitative datasets ..... whereby both types of data are collected simultaneously.

  19. Comparative research and the business system approach

    DEFF Research Database (Denmark)

    Rocha, Robson Silva

    2003-01-01

    This paper has two distinct aims. First, I would like to present and discuss the nationalbusiness systems (NBS) framework ( Whitley, 1992,1992a,1996,1997). NBS frameworkconcerns how national variations in economic co-ordination and control systemsfacilitate and constrain organisational change....... The NBS is not widely known in the LatinAmerica countries, and this paper intends to shortly present it The second aim is toquestion, based on the NBS approach, some of the assumptions about the diffusion of anew universal template for organising work (Lean Production) and its agent, themultinational...

  20. Surgery in biliary lithiasis: from the traditional "open" approach to laparoscopy and the "rendezvous" technique.

    Science.gov (United States)

    Tarantino, Giuseppe; Magistri, Paolo; Ballarin, Roberto; Assirati, Giacomo; Di Cataldo, Antonio; Di Benedetto, Fabrizio

    2017-12-15

    According to the current literature, biliary lithiasis is a worldwide-diffused condition that affects almost 20% of the general population. The rate of common bile duct stones (CBDS) in patients with symptomatic cholelithiasis is estimated to be 10% to 33%, depending on patient's age. Compared to stones in the gallbladder, the natural history of secondary CBDS is still not completely understood. It is not clear whether an asymptomatic choledocholithiasis requires treatment or not. For many years, open cholecystectomy with choledochotomy and/or surgical sphincterotomy and cleaning of the bile duct were the gold standard to treat both pathologies. Development of both endoscopic retrograde cholangiopancreatography (ERCP) and laparoscopic surgery, together with improvements in diagnostic procedures, influenced new approaches to the management of CBDS in association with gallstones. We decided to systematically review the literature in order to identify all the current therapeutic options for CBDS. A systematic literature search was performed independently by two authors using PubMed, EMBASE, Scopus and the Cochrane Library Central. The therapeutic approach nowadays varies greatly according to the availability of experience and expertise in each center, and includes open or laparoscopic common bile duct exploration, various combinations of laparoscopic cholecystectomy and ERCP and combined laparoendoscopic rendezvous. Although ERCP followed by laparoscopic cholecystectomy is currently preferred in the majority of hospitals worldwide, the optimal treatment for concomitant gallstones and CBDS is still under debate, and greatly varies among different centers. Copyright © 2017 The Editorial Board of Hepatobiliary & Pancreatic Diseases International. Published by Elsevier B.V. All rights reserved.

  1. Sustainability or Colonialism? Legislative obstacles to research and development of natural products and patents on traditional knowledge in Brazil

    Directory of Open Access Journals (Sweden)

    Camilo Tomazini Pedrollo

    2015-09-01

    Full Text Available ABSTRACTHistorically, developed countries have benefited from the biodiversity and traditional knowledge of developing countries. Since the Convention on Biological Diversity (CBD was approved, the world-view regarding access to biological resources has changed. This change marked the introduction of legal agreements regarding access to genetic resources, traditional knowledge and benefit sharing, seeking a fair return for owners and local communities. Unfortunately, as with most national laws, these legal devices complicated collection programs and research initiatives, and diminished the emphasis on the discovery of natural products. There remains a lack of discussion on the establishment of a fair international market value for the access to genetic resources. While Brazil still has advantages and opportunities in this arena, the issue sets barriers for research and development. The protective measures are being reviewed in the project bill 7735/2014, which brings improvements, yet it is still controversial. For this short communication we consulted journals, conference proceedings, as well as scientific and journalistic magazines to report some of the disastrous consequences of the implementation of national laws regarding CBD. We suggest a new focus for decision-making policies based on more efficient field inspections, the empowerment of traditional communities and further associated research in order to ensure the claims of CBD as well as to ratify the Nagoya Protocol.

  2. Researching media through practices: an ethnographic approach

    Directory of Open Access Journals (Sweden)

    Antoni Roig

    2009-05-01

    Full Text Available Anthropological and ethnographic research on media have been largely focused on analyzing reception of media products (television, radio, press and film and media consumption related to domestic appropriation of technologies (Rothenbuhler et al., 2005. There is also a wide body of research devoted to the study of the political dimension of alternative and indigenous media (Ginsburg, 2002. However, there has been a separation between media and internet studies, and between the analysis of media reception and practices of self-production, such as family photography or home video. Current digital media practices urge reexamination of self-produced content and media flows from a broader perspective that cuts across divisions between public and private, corporative media products and people's releases, home production and cultural industry, political activism and everyday life.

  3. Experience inheritance from famous specialists based on real-world clinical research paradigm of traditional Chinese medicine.

    Science.gov (United States)

    Song, Guanli; Wang, Yinghui; Zhang, Runshun; Liu, Baoyan; Zhou, Xuezhong; Zhou, Xiaji; Zhang, Hong; Guo, Yufeng; Xue, Yanxing; Xu, Lili

    2014-09-01

    The current modes of experience inheritance from famous specialists in traditional Chinese medicine (TCM) include master and disciple, literature review, clinical-epidemiology-based clinical research observation, and analysis and data mining via computer and database technologies. Each mode has its advantages and disadvantages. However, a scientific and instructive experience inheritance mode has not been developed. The advent of the big data era as well as the formation and practice accumulation of the TCM clinical research paradigm in the real world have provided new perspectives, techniques, and methods for inheriting experience from famous TCM specialists. Through continuous exploration and practice, the research group proposes the innovation research mode based on the real-world TCM clinical research paradigm, which involves the inheritance and innovation of the existing modes. This mode is formulated in line with its own development regularity of TCM and is expected to become the main mode of experience inheritance in the clinical field.

  4. [Application of qualitative interviews in inheritance research of famous old traditional Chinese medicine doctors: ideas and experience].

    Science.gov (United States)

    Luo, Jing; Fu, Chang-geng; Xu, Hao

    2015-04-01

    The inheritance of famous old traditional Chinese medicine (TCM) doctors plays an essential role in the fields of TCM research. Qualitative interviews allow for subjectivity and individuality within clinical experience as well as academic ideas of doctors, making it a potential appropriate research method for inheritance of famous old TCM doctors. We summarized current situations of inheritance research on famous old TCM doctors, and then discussed the feasibility of applying qualitative interviews in inheritance of famous old TCM doctors. By combining our experience in research on inheritance of famous old TCM doctors, we gave some advice on study design, interview implementation, data transcription and analyses , and report writing, providing a reference for further relevant research.

  5. Research advances in traditional Chinese medicine combined with interventional therapy for hepatocellular carcinoma

    Directory of Open Access Journals (Sweden)

    LIU Yang

    2015-01-01

    Full Text Available Interventional therapy has become the first choice of non-surgical treatment for hepatocellular carcinoma (HCC due to its advantages such as little trauma and marked local effect. However, the clinical efficiency is less than expected. One of the possibilities is the resistance of cancer cells to anti-cancer drugs. Increasing attention has been paid to the combination of traditional Chinese medicine (TCM and interventional therapy in HCC treatment. This paper reviews the progress in TCM combined with interventional therapy for HCC at animal experiment and clinical study levels in recent ten years. It is pointed out that the combination therapy with TCM and intervention for HCC has a unique advantage.

  6. Using the Pyramid Approach to Teaching Marketing Research.

    Science.gov (United States)

    Peltier, James W.; Westfall, John; Ainscough, Thomas L.

    2001-01-01

    Underscores the need for teaching marketing research skills at the secondary level and shows how marketing research fits into marketing education. Provides an example of how to use the pyramid approach to research, which involves review of secondary sources, key informant interviews, focus groups, and quantitative research. (Author/JOW)

  7. Comparison of student outcomes and preferences in a traditional vs. World Wide Web-based baccalaureate nursing research course.

    Science.gov (United States)

    Leasure, A R; Davis, L; Thievon, S L

    2000-04-01

    The purpose of this project was to compare student outcomes in an undergraduate research course taught using both World Wide Web-based distance learning technology and traditional pedagogy. Reasons given for enrolling in the traditional classroom section included the perception of increased opportunity for interaction, decreased opportunity to procrastinate, immediate feedback, and more meaningful learning activities. Reasons for selecting the Web group section included cost, convenience, and flexibility. Overall, there was no significant difference in examination scores between the two groups on the three multiple-choice examinations or for the course grades (t = -.96, P = .343). Students who reported that they were self-directed and had the ability to maintain their own pace and avoid procrastination were most suited to Web-based courses. The Web-based classes can help provide opportunities for methods of communication that are not traditionally nurtured in traditional classroom settings. Secondary benefits of the World Wide Web-based course were to increase student confidence with the computer, and introduce them to skills and opportunities they would not have had in the classroom. Additionally, over time and with practice, student's writing skills improved.

  8. Hybrid soft computing approaches research and applications

    CERN Document Server

    Dutta, Paramartha; Chakraborty, Susanta

    2016-01-01

    The book provides a platform for dealing with the flaws and failings of the soft computing paradigm through different manifestations. The different chapters highlight the necessity of the hybrid soft computing methodology in general with emphasis on several application perspectives in particular. Typical examples include (a) Study of Economic Load Dispatch by Various Hybrid Optimization Techniques, (b) An Application of Color Magnetic Resonance Brain Image Segmentation by ParaOptiMUSIG activation Function, (c) Hybrid Rough-PSO Approach in Remote Sensing Imagery Analysis,  (d) A Study and Analysis of Hybrid Intelligent Techniques for Breast Cancer Detection using Breast Thermograms, and (e) Hybridization of 2D-3D Images for Human Face Recognition. The elaborate findings of the chapters enhance the exhibition of the hybrid soft computing paradigm in the field of intelligent computing.

  9. Theoretical approaches to e-book research

    Directory of Open Access Journals (Sweden)

    Tom D Wilson

    2016-12-01

    Full Text Available The adoption and continued use of innovations by societies, organisations and individuals has been a subject of research since before the 1930s. A variety of different theories have been developed to account for the different speeds at which innovations are adopted and the factors that affect the adoption process. This paper reviews theories of the adoption of innovations with particular reference to the recent phenomenon of the e-book as a cultural innovation that is having an impact on individuals, organizations and national policy makers. The paper will suggest which theories are most appropriate for the different levels at which the innovation is employed.

  10. [Taking evaluation of post-marketing as point of cut-in to promote systematic research of traditional Chinese medicine].

    Science.gov (United States)

    Wang, Yong-yan; Wang, Zhi-fei; Xie, Yan-ming

    2014-09-01

    Research on post-marketing Chinese medicine should be the systematic study from application to mechanism. Clinical evaluation is the basis of mechanism study, we can find the clue from clinical evaluation, then make a mechanism study to find the reason, then apply the results to clinic. So it is a virtuous circle. In order to achieve it, we cannot be limited to traditional Chinese medicine, we should form multi-disciplinary team under the direction of grand science thinking, try hard to put industry-university-research institute collaboration association to use, and if necessary, explore the new model of the whole nation system. An appropriate operation mechanism is very important.

  11. The Shaping of the Scandinavian Socio-technical IS Research Tradition

    DEFF Research Database (Denmark)

    Bjørn-Andersen, Niels; Clemmensen, Torkil

    2017-01-01

    voice of the autoethnographer and the questioning voice of a younger researcher, the second author, who wants to bridge S/T into the future. The main contributions of this paper are to provide: 1) insights into career development in IS in general and in one of the Scandinavian IS pioneers in particular......This paper relates stories instrumental in shaping the career of an individual and which have also contributed to shaping of the IS field in general and the ‘Scandinavian Socio-Technical (S/T) Information Systems Research Tradition’ in particular. The method in this paper is an autoethnography......; 2) a historic account of some of the key events in the early days of S/T IS in Scandinavia; 3) an account of the experiences and the challenges in creating a new research field such as IS; and 4) a summary of Niels’s key learnings hopefully relevant to young and mid-career IS researchers....

  12. [Discussion on research and development of new traditional Chinese medicine preparation process based on idea of QbD].

    Science.gov (United States)

    Feng, Yi; Hong, Yan-Long; Xian, Jie-Chen; Du, Ruo-Fei; Zhao, Li-Jie; Shen, Lan

    2014-09-01

    Traditional processes are mostly adopted in traditional Chinese medicine (TCM) preparation production and the quality of products is mostly controlled by terminal. Potential problems of the production in the process are unpredictable and is relied on experience in most cases. Therefore, it is hard to find the key points affecting the preparation process and quality control. A pattern of research and development of traditional Chinese medicine preparation process based on the idea of Quality by Design (QbD) was proposed after introducing the latest research achievement. Basic theories of micromeritics and rheology were used to characterize the physical property of TCM raw material. TCM preparation process was designed in a more scientific and rational way by studying the correlation among enhancing physical property of raw material, preparation process and product quality of preparation. So factors affecting the quality of TCM production would be found out and problems that might occur in the pilot process could be predicted. It would be a foundation for the R&D and production of TCM preparation as well as support for the "process control" of TCMIs gradually realized in the future.

  13. Managing Cybersecurity Research and Experimental Development: The REVO Approach

    OpenAIRE

    Dan Craigen; Drew Vandeth; D’Arcy Walsh

    2013-01-01

    We present a systematic approach for managing a research and experimental development cybersecurity program that must be responsive to continuously evolving cybersecurity, and other, operational concerns. The approach will be of interest to research-program managers, academe, corporate leads, government leads, chief information officers, chief technology officers, and social and technology policy analysts. The approach is compatible with international standards and procedures published by the...

  14. [Discussion on research thinking of traditional Chinese medicine standardization system based on whole process quality control].

    Science.gov (United States)

    Dong, Ling; Sun, Yu; Pei, Wen-Xuan; Dai, Jun-Dong; Wang, Zi-Yu; Pan, Meng; Chen, Jiang-Peng; Wang, Yun

    2017-12-01

    The concept of "Quality by design" indicates that good design for the whole life cycle of pharmaceutical production enables the drug to meet the expected quality requirements. Aiming at the existing problems of the traditional Chinese medicine (TCM) industry, the TCM standardization system was put forward in this paper from the national strategic level, under the guidance by the idea of quality control in international manufacturing industry and with considerations of TCM industry's own characteristics and development status. The connotation of this strategy was to establish five interrelated systems: multi-indicators system based on tri-indicators system, quality standard and specification system of TCM herbal materials and decoction pieces, quality traceability system, data monitoring system based on whole-process quality control, and whole-process quality management system of TCM, and achieve the whole process systematic and scientific study in TCM industry through "top-level design-implement in steps-system integration" workflow. This article analyzed the correlation between the quality standards of all links, established standard operating procedures of each link and whole process, and constructed a high standard overall quality management system for TCM industry chains, in order to provide a demonstration for the establishment of TCM whole-process quality control system and provide systematic reference and basis for standardization strategy in TCM industry. Copyright© by the Chinese Pharmaceutical Association.

  15. [Modern research progress of traditional Chinese medicine based on integrative pharmacology].

    Science.gov (United States)

    Wang, Ping; Tang, Shi-Huan; Su, Jin; Zhang, Jia-Qi; Cui, Ru-Yi; Xu, Hai-Yu; Yang, Hong-Jun

    2018-04-01

    Integrative pharmacology (IP) is a discipline that studies the interaction, integration and principle of action of multiple components with the body, emphasizing the integrations of multi-level and multi-link, such as "whole and part", " in vivo and in vitro ", " in vivo process and activity evaluation". After four years of development and practice, the theory and method of IP has received extensive attention and application.In order to better promote the development of IP, this paper systematically reviews the concepts, research contents, research methods and application fields about IP. Copyright© by the Chinese Pharmaceutical Association.

  16. Research on the improvement of traditional dial instrument precision based on C8051F020.

    Science.gov (United States)

    Sun, Guiling; Liu, Yi; Lu, Li

    2006-11-01

    Two essential parameters to weigh the quality of a reinforcing steel bar are the value of its bending force and the maximum pull it can withstand, in order to measure them with higher precision, it is significant to describe the changing tendency of force with time and displacement by drawing a real-time curve directly during the process examining the quality of a bar when the pull exerted is variable continuously. Using C8051F020 as the core component, this paper improves traditional dial instruments whose precision can only reach the second level. Adopting a high precision pulling/pressing force sensor, an amplifier, a two-order Butterworth low-pass filter and a 12-bit AD converter which is in the C8051F020, the first level of precision can be obtained. A rotary encoder is used to measure the length increment of the bar during the pulling process, based on an algorithm, a force-displacement (or time) curve which is quite important for operators to control the course of experiment can be displayed on the LCD. Meanwhile, real-time experimental data can be stored in local flash, or uploaded to PC by RS-485 and stored in the center database. A real-time clock is also adopted to mark the time of each experiment that is useful to index the data. The measure system we describe here is characterized by simple structure, high precision and stabilization, and convenience operation, can be used in other actual measure systems by only changing the front sensor, so it is of great value of application and popularization.

  17. Comparison of harmonic blade versus traditional approach in canine patients undergoing spinal decompressive surgery for naturally occurring thoracolumbar disk extrusion.

    Directory of Open Access Journals (Sweden)

    Bianca F Hettlich

    Full Text Available To assess feasibility of the harmonic Osteovue blade (HOB for use in the soft tissue approach for dogs undergoing hemilaminectomy and to compare outcomes between dogs undergoing HOB or traditional approach (TRAD.A prospective randomized clinical trial was performed using 20 client-owned dogs with thoracolumbar intervertebral disk extrusion requiring hemilaminectomy. Dogs were randomly assigned to HOB or TRAD. Neurologic function and pain scores were assessed pre-operatively. Intraoperative blood loss and surgical approach time as well as postoperative pain and wound healing scores were recorded. Additionally, neurologic recovery and owner perceived quality of life were recorded at day 10 and 30 postoperative.There was no significant difference in sex distribution, weight, age, preoperative neurological grade and pain score, and perioperative outcome measures between groups. Intraoperative total blood loss was minimal for HOB and TRAD (median: 0 ml (range 0-9 and 2.2 ml (range 0-6.8, respectively; p = 0.165 and approach times were similar (median: 7 min (range 5-12 and 8 min (range 5-13, respectively; p = 0.315. While changes in wound healing scores were similar, changes in postoperative pain scores and neurological function were significantly improved in the HOB compared to the TRAD group. Postoperative complications in the HOB group consisted of automutilation of part of the incision and development of a small soft, non-painful subcutaneous swelling in 1 dog each.The HOB is a safe and effective tool for the soft tissue approach for routine spinal surgery in dogs and is associated with decreased pain and increased neurological function post-surgery.

  18. Public Administration and Public Management Research in Europe: Traditions and Trends

    NARCIS (Netherlands)

    Ongaro, E.; Thiel, S. van; Massey, A.; Pierre, J.; Wollmann, H.; Ongaro, E.; Thiel, S. van

    2018-01-01

    The chapter reviews the evolution of the state of the art of research in public administration and management in Europe since WWII. It argues that a pan-European community has developed, flanking and in many respects integrating the distinct national communities that characterised the field till the

  19. Cul-De-Sac from Diehard Traditions: The Demise of Action Research in Teacher Education

    Science.gov (United States)

    Zireva, Davison

    2017-01-01

    Reflective practice has become the global prime educational trend expected of education practitioners but some teacher educators tend to stifle its development. It is strongly believed in critical pedagogy, the theoretical framework of action research theorists that reflective practice is inherent in an introspective disposition and is developed…

  20. Systematic Approach to Research Training: Benefits for Counseling Practice.

    Science.gov (United States)

    Loughead, Teri A.; And Others

    1991-01-01

    Synthesizes developments concerning research training in graduate counselor education and presents a systematic approach for training master's and doctoral students in mental health counseling to assimilate, use, and perform research. Suggests diversity of research training strategies for implementation in counselor preparation programs.…

  1. Beyond Compliance Checking: A Situated Approach to Visual Research Ethics.

    Science.gov (United States)

    Lenette, Caroline; Botfield, Jessica R; Boydell, Katherine; Haire, Bridget; Newman, Christy E; Zwi, Anthony B

    2018-03-19

    Visual research methods like photography and digital storytelling are increasingly used in health and social sciences research as participatory approaches that benefit participants, researchers, and audiences. Visual methods involve a number of additional ethical considerations such as using identifiable content and ownership of creative outputs. As such, ethics committees should use different assessment frameworks to consider research protocols with visual methods. Here, we outline the limitations of ethics committees in assessing projects with a visual focus and highlight the sparse knowledge on how researchers respond when they encounter ethical challenges in the practice of visual research. We propose a situated approach in relation to visual methodologies that encompasses a negotiated, flexible approach, given that ethical issues usually emerge in relation to the specific contexts of individual research projects. Drawing on available literature and two case studies, we identify and reflect on nuanced ethical implications in visual research, like tensions between aesthetics and research validity. The case studies highlight strategies developed in-situ to address the challenges two researchers encountered when using visual research methods, illustrating that some practice implications are not necessarily addressed using established ethical clearance procedures. A situated approach can ensure that visual research remains ethical, engaging, and rigorous.

  2. Teaching Psychological Research Methods through a Pragmatic and Programmatic Approach

    Science.gov (United States)

    Rosenkranz, Patrick; Fielden, Amy; Tzemou, Effy

    2014-01-01

    Research methods teaching in psychology is pivotal in preparing students for the transition from student as learner to independent practitioner. We took an action research approach to re-design, implement and evaluate a module guiding students through a programmatic and pragmatic research cycle. These revisions allow students to experience how…

  3. Beyond Traditional Advertisements: Leveraging Facebook’s Social Structures for Research Recruitment

    Science.gov (United States)

    Guterbock, Thomas M; Thompson, Morgan J; Reilly, Jeremiah D; Menefee, Hannah K; Bennici, Maria S; Williams, Ishan C; Rexrode, Deborah L

    2014-01-01

    Background Obtaining access to a demographically and geographically diverse sample for health-related research can be costly and time consuming. Previous studies have reported mixed results regarding the potential of using social media-based advertisements to overcome these challenges. Objective Our aim was to develop and assess the feasibility, benefits, and challenges of recruiting for research studies related to consumer health information technology (IT) by leveraging the social structures embedded in the social networking platform, Facebook. Methods Two recruitment strategies that involved direct communication with existing Facebook groups and pages were developed and implemented in two distinct populations. The first recruitment strategy involved posting a survey link directly to consenting groups and pages and was used to recruit Filipino-Americans to a study assessing the perceptions, use of, and preferences for consumer health IT. This study took place between August and December 2013. The second recruitment strategy targeted individuals with type 2 diabetes and involved creating a study-related Facebook group and asking administrators of other groups and pages to publicize our group to their members. Group members were then directly invited to participate in an online pre-study survey. This portion of a larger study to understand existing health management practices as a foundation for consumer health IT design took place between May and June 2014. In executing both recruitment strategies, efforts were made to establish trust and transparency. Recruitment rate, cost, content of interaction, and characteristics of the sample obtained were used to assess the recruitment methods. Results The two recruitment methods yielded 87 and 79 complete responses, respectively. The first recruitment method yielded a rate of study completion proportionate to that of the rate of posts made, whereas recruitment successes of the second recruitment method seemed to follow

  4. Approach to a State of the Art of Traditional and Popular Medicinal Practices in Hispano-American

    Directory of Open Access Journals (Sweden)

    Omar Alberto Garzón Chirivi

    2015-04-01

    Full Text Available DOI: http://dx.doi.org/10.17227/01234870.41folios157.168 This article presents a state of the art of academic production concerning traditional and popular medicine in Latin America. It analyzes the relation between studies on chamanismo (the art of medicine men in indigenous communities in some Spanish-speaking countries (Colombia, Peru, Bolivia, Mexico, Spain and studies on curanderismo (the art of healers in urban contexts and evidences recurring elements of a magical, religious and medical kind in their therapeutic practices. Likewise, it shows the changes in the understanding of these systems of treatment and assistance to health and sickness, their permanence and incidence on collective practices associated to spirituality, as well as the construction of alternatives of individual and social health and the interdisciplinary character of the existing research studies. This article, too, proposes the existence of an analytical vacuum regarding gender, class and ethnic group in the studies on traditional and popular medicine.

  5. Culture of National Philosophical Communities: the Project Dedicated to the Research of Modern Ukrainian Philosophical Traditions

    Directory of Open Access Journals (Sweden)

    Lidiya Bogataya

    2018-04-01

    Full Text Available The article introduces a new Ukrainian research project related to the preparation of a collective monograph. This monograph will highlight the activities of modern Ukrainian philosophical communities. Such communities in their totality constitute a modern national philosophical culture and its study belongs to the category of macro-humanitarian research. The basis for a holistic observation of a culture is, on the one hand, digital technologies that enable technically to take into account practically all the studies that are carried out in a particular field in a certain period of time. On the other hand, new methodological developments are emerging that allow us to quickly process large text arrays. An example of such methodological innovations can be considered the study of American-Italian literary critic Franco Moretti. Moretti examines the opportunities that arise when using “distant reading.” The article emphasizes that the main advantage of “distant reading” is the possibility of taking into account the whole body of texts, and not only its canonical kernel. Introduces the idea of «compression reading» as a special kind of “rapid reading”, which allows you to get the most general idea of the text based on the analysis of the title of the text and its annotation. The development of compression reading technologies along with distant reading technologies will allow efficient and efficient processing of large array of texts. The expediency of actualization of the whole textual array formed in this or that humanitarian field of research is associated with the development of a new ethic. This ethic is the ethic of collective labor. A new understanding of the collective is considered, which is possible only with careful consideration of any manifestation of the individual

  6. Seeking Constructive Synergy: Design Science and the Constructive Research Approach

    DEFF Research Database (Denmark)

    Piirainen, Kalle; Gonzalez, Rafael A.

    2013-01-01

    Information systems research and management science create knowledge which can be applied in organizations. Design science specifically aims at applying existing knowledge to solve interesting and relevant business problems and has been steadily gaining support in information systems research....... However, design science is not the only design-oriented framework. Accordingly, this raises the question of whether it is possible to compare the results obtained from different brands of design-oriented research. This paper contributes to answering this question by comparing two research approaches......, enabling mutual learning possibilities and suggesting improvements in transparency and rigor. The objective of this paper is to compare design science research with the constructive research approach. The conclusion is that the two approaches are compatible, save for details in practical requirements...

  7. A collaborative approach for research paper recommender system.

    Science.gov (United States)

    Haruna, Khalid; Akmar Ismail, Maizatul; Damiasih, Damiasih; Sutopo, Joko; Herawan, Tutut

    2017-01-01

    Research paper recommenders emerged over the last decade to ease finding publications relating to researchers' area of interest. The challenge was not just to provide researchers with very rich publications at any time, any place and in any form but to also offer the right publication to the right researcher in the right way. Several approaches exist in handling paper recommender systems. However, these approaches assumed the availability of the whole contents of the recommending papers to be freely accessible, which is not always true due to factors such as copyright restrictions. This paper presents a collaborative approach for research paper recommender system. By leveraging the advantages of collaborative filtering approach, we utilize the publicly available contextual metadata to infer the hidden associations that exist between research papers in order to personalize recommendations. The novelty of our proposed approach is that it provides personalized recommendations regardless of the research field and regardless of the user's expertise. Using a publicly available dataset, our proposed approach has recorded a significant improvement over other baseline methods in measuring both the overall performance and the ability to return relevant and useful publications at the top of the recommendation list.

  8. Approaches to pre-formulation R and D for phytopharmaceuticals emanating from herb based traditional Ayurvedic processes

    Directory of Open Access Journals (Sweden)

    D B Anantha Narayana

    2013-01-01

    Full Text Available Botanicals constitute a large part of the drugs from the traditional medicine (TM and ethno medicine (EM known for their history of safe use (HOSU. Phytopharmaceuticals having a base of such origin offer high advantages as they come with safety profiles, and often allow extrapolation of the HOSU data, under certain circumstances. However, while current pharmaceutical technologies are being adopted by the industry to make phytopharmaceuticals with such origin, there is a need for preformulation research and development (R and D during formulation. Some suggestions for R and D studies in case of aqueous extracts known in Ayurveda, converted on an industrial scale to obtain a phytopharmaceutical, and formulated as a solid dosage form (granules, tablets, or capsules are discussed.

  9. Contributions of Indian Council of Medical Research (ICMR) in the area of Medicinal plants/Traditional medicine.

    Science.gov (United States)

    Tandon, Neeraj; Yadav, Satyapal Singh

    2017-02-02

    Medicinal plants belong to the oldest known health care products that have been used by human beings all over the world and are major components of the formulations used in indigenous system of medicine practiced in many countries. Besides, finding place as health supplements, nutraceuticals, cosmetics, herbal tea etc. there has been a global insurgence of interest, including India, leading to enormous research/activities in the area of medicinal plants. The article is aimed to provide the effort and initiatives of ICMR towards research on medicinal plants and its contributions on consolidation of Indian research on medicinal plants that are very relevant and important in the national context. The various initiatives undertaken by ICMR on research on traditional medicines/medicinal plants in the past are reviewed and documented in this article. The multi-disciplinary, multicentric research initiatives of ICMR have resulted in validation of traditional treatment Kshaarasootra (medicated Ayurvedic thread) for anal fistula, Vijayasar (heart wood of Pterocarpus marsupium Roxb.) for diabetes mellitus, encouraging micro- and macrofilaricidal activity of Shakotak (stem bark of Streblus asper Lour.) in experimental studies an iridoid glycosides fraction isolated from root/rhizomes of Picrorhiza kurroa Royle ex Benth. (designated as Picroliv) for viral hepatitis. Other developmental and compilation of research works on Indian medicinal plants have resulted in publications of the thirteen volumes of quality standards, comprising of 449 Indian medicinal plants; three volumes of 90 phytochemical reference standards; fifteen volumes of review monographs on 4167 medicinal plant species; and one publication each on perspectives of Indian medicinal plants for management of liver disorders, lymphatic filariasis and diabetes mellitus (details available at http://www.icmr.nic.in/mpsite). The ICMR efforts assume special significance in the light of multifaceted use of medicinal plants

  10. A Comparison Study: The New Extended Shelf Life Isopropyl Ester PMR Technology versus The Traditional Methyl Ester PMR Approach

    Science.gov (United States)

    Alston, William B.; Scheiman, Daniel A.; Sivko, Gloria S.

    2005-01-01

    Polymerization of Monomeric Reactants (PMR) monomer solutions and carbon cloth prepregs of PMR II-50 and VCAP-75 were prepared using both the traditional limited shelf life methanol based PMR approach and a novel extended shelf life isopropanol based PMR approach. The methyl ester and isopropyl ester based PMR monomer solutions and PMR prepregs were aged for up to four years at freezer and room temperatures. The aging products formed were monitored using high pressure liquid chromatography (HPLC). The composite processing flow characteristics and volatile contents of the aged prepregs were also correlated versus room temperature storage time. Composite processing cycles were developed and six ply cloth laminates were fabricated with prepregs after various extended room temperature storage times. The composites were then evaluated for glass transition temperature (Tg), thermal decomposition temperature (Td), initial flexural strength (FS) and modulus (FM), long term (1000 hours at 316 C) thermal oxidative stability (TOS), and retention of FS and FM after 1000 hours aging at 316 C. The results for each ester system were comparable. Freezer storage was found to prevent the formation of aging products for both ester systems. Room temperature storage of the novel isopropyl ester system increased PMR monomer solution and PMR prepreg shelf life by at least an order of magnitude while maintaining composite properties.

  11. Capitalising on multiplicity: an transdisciplinary systems approach to landscape research

    NARCIS (Netherlands)

    Tress, B.; Tress, G.

    2001-01-01

    Different disciplines have landscape as the focal point of their research. They are successful in presenting new findings about landscapes within their specialization, but collaboration - and thus, transfer of knowledge across disciplinary boundaries - is seldom realized because a common approach

  12. Conducting Research with young people and developing the MTW Approach

    DEFF Research Database (Denmark)

    Frostholm, Peter Hornbæk; Mikkelsen, Sidse Hølvig; Gravesen, David Thore

    2017-01-01

    Abstract In this article we present our qualitative mixed-methods methodology that we name the Map-Talk-Walk Approach (MTW Approach). We developed the approach to better grasp young people’s understandings of youth, normality and belonging, which make up the thematic framework of our current youth...... research. The MTW Approach is based on three phases, 1) Researcher-initiated workshops, 2) Focus group interviews, and 3) Walk-and-talks in the young people’s local environments. In the article, we discuss the ethical complications related to doing research with young people and positioning them as experts...... in their life worlds. Our ambition is to create a democratized research process that allows the participants ownership, and we find this to be a challenging task. In the closing section, after a thorough presentation of the three phases, we discuss some of the pitfalls we experienced during the process...

  13. Traditional grains boost nutrition in rural India

    International Development Research Centre (IDRC) Digital Library (Canada)

    India, particularly among vulnerable women and children. The research ... This approach will improve the quality of life for farmers, and is part of a long-term solution to rural poverty in India. ... Traditional grains boost nutrition in rural India.

  14. A META-COMPOSITE SOFTWARE DEVELOPMENT APPROACH FOR TRANSLATIONAL RESEARCH

    Science.gov (United States)

    Sadasivam, Rajani S.; Tanik, Murat M.

    2013-01-01

    Translational researchers conduct research in a highly data-intensive and continuously changing environment and need to use multiple, disparate tools to achieve their goals. These researchers would greatly benefit from meta-composite software development or the ability to continuously compose and recompose tools together in response to their ever-changing needs. However, the available tools are largely disconnected, and current software approaches are inefficient and ineffective in their support for meta-composite software development. Building on the composite services development approach, the de facto standard for developing integrated software systems, we propose a concept-map and agent-based meta-composite software development approach. A crucial step in composite services development is the modeling of users’ needs as processes, which can then be specified in an executable format for system composition. We have two key innovations. First, our approach allows researchers (who understand their needs best) instead of technicians to take a leadership role in the development of process models, reducing inefficiencies and errors. A second innovation is that our approach also allows for modeling of complex user interactions as part of the process, overcoming the technical limitations of current tools. We demonstrate the feasibility of our approach using a real-world translational research use case. We also present results of usability studies evaluating our approach for future refinements. PMID:23504436

  15. A meta-composite software development approach for translational research.

    Science.gov (United States)

    Sadasivam, Rajani S; Tanik, Murat M

    2013-06-01

    Translational researchers conduct research in a highly data-intensive and continuously changing environment and need to use multiple, disparate tools to achieve their goals. These researchers would greatly benefit from meta-composite software development or the ability to continuously compose and recompose tools together in response to their ever-changing needs. However, the available tools are largely disconnected, and current software approaches are inefficient and ineffective in their support for meta-composite software development. Building on the composite services development approach, the de facto standard for developing integrated software systems, we propose a concept-map and agent-based meta-composite software development approach. A crucial step in composite services development is the modeling of users' needs as processes, which can then be specified in an executable format for system composition. We have two key innovations. First, our approach allows researchers (who understand their needs best) instead of technicians to take a leadership role in the development of process models, reducing inefficiencies and errors. A second innovation is that our approach also allows for modeling of complex user interactions as part of the process, overcoming the technical limitations of current tools. We demonstrate the feasibility of our approach using a real-world translational research use case. We also present results of usability studies evaluating our approach for future refinements.

  16. Developing, Approving and Maintaining Qualifications: Selected International Approaches. Research Report

    Science.gov (United States)

    Misko, Josie

    2015-01-01

    There are lessons for Australia in the key approaches to the development, approval, maintenance and quality assurance of qualifications adopted in countries overseas. This research takes into account a range of approaches used in selected European Union (EU) member states (Germany, Finland and Sweden), the United Kingdom (England, Northern Ireland…

  17. Compare and Contrast Inductive and Deductive Research Approaches

    Science.gov (United States)

    Soiferman, L. Karen

    2010-01-01

    This discussion paper compares and contrasts "inductive" and "deductive" research approaches as described by Trochim (2006) and Plano Clark and Creswell (2007). It also examines the "exploratory" and "confirmatory" approaches by Onwueghuzie and Leech (2005) with respect to the assumption each holds about the nature of knowledge. The paper starts…

  18. Propensity Score Analysis: An Alternative Statistical Approach for HRD Researchers

    Science.gov (United States)

    Keiffer, Greggory L.; Lane, Forrest C.

    2016-01-01

    Purpose: This paper aims to introduce matching in propensity score analysis (PSA) as an alternative statistical approach for researchers looking to make causal inferences using intact groups. Design/methodology/approach: An illustrative example demonstrated the varying results of analysis of variance, analysis of covariance and PSA on a heuristic…

  19. Exploring Action Research as an Approach to Interactive (Participatory) Evaluation

    Science.gov (United States)

    Chaudary, Imran Anjum; Imran, Shahida

    2012-01-01

    This investigation seeks to understand "action research" as an approach to "interactive form of evaluation". The first half of the investigation illuminates the approach with the help of the selective body of literature and the second half draws attention to its application in the field with the help of an authentic evaluation…

  20. New technique targeting the C5 nerve root proximal to the traditional interscalene sonoanatomical approach is analgesic for outpatient arthroscopic shoulder surgery.

    Science.gov (United States)

    Dobie, Katherine H; Shi, Yaping; Shotwell, Matthew S; Sandberg, Warren S

    2016-11-01

    Regional anesthesia and analgesia for shoulder surgery is most commonly performed via interscalene nerve block. We developed an ultrasound-guided technique that specifically targets the C5 nerve root proximal to the traditional interscalene block and assessed its efficacy for shoulder analgesia. Prospective case series. Vanderbilt Bone and Joint Surgery Center. Patients undergoing shoulder arthroscopy at an ambulatory surgery center. Thirty-five outpatient shoulder arthroscopy patients underwent an analgesic nerve block using a new technique where ultrasound visualization of the C5 nerve root served as the primary target at a level proximal to the traditional interscalene approach. The block was performed with 15mL of 0.5% plain ropivicaine. Post anesthesia care unit pain scores, opioid consumption, hand strength, and duration of block were recorded. Cadaver dissection after injection with methylene blue confirmed that the primary target under ultrasound visualization was the C5 nerve root. Pain scores revealed 97% patients had 0/10 pain at arrival to PACU, with 91% having a pain score of 3/10 or less at discharge from PACU. Medical Research Council (MRC) hand strength mean (SD) score was 4.17 (0.92) on a scale of 1-5. The mean (SD) duration of the block was 13.9 (3.5) hours. A new technique for ultrasound-guided blockade at the level of the C5 nerve root proximal to the level of the traditional interscalene block is efficacious for shoulder post-operative pain control. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. Beyond Traditional Extreme Value Theory Through a Metastatistical Approach: Lessons Learned from Precipitation, Hurricanes, and Storm Surges

    Science.gov (United States)

    Marani, M.; Zorzetto, E.; Hosseini, S. R.; Miniussi, A.; Scaioni, M.

    2017-12-01

    The Generalized Extreme Value (GEV) distribution is widely adopted irrespective of the properties of the stochastic process generating the extreme events. However, GEV presents several limitations, both theoretical (asymptotic validity for a large number of events/year or hypothesis of Poisson occurrences of Generalized Pareto events), and practical (fitting uses just yearly maxima or a few values above a high threshold). Here we describe the Metastatistical Extreme Value Distribution (MEVD, Marani & Ignaccolo, 2015), which relaxes asymptotic or Poisson/GPD assumptions and makes use of all available observations. We then illustrate the flexibility of the MEVD by applying it to daily precipitation, hurricane intensity, and storm surge magnitude. Application to daily rainfall from a global raingauge network shows that MEVD estimates are 50% more accurate than those from GEV when the recurrence interval of interest is much greater than the observational period. This makes MEVD suited for application to satellite rainfall observations ( 20 yrs length). Use of MEVD on TRMM data yields extreme event patterns that are in better agreement with surface observations than corresponding GEV estimates.Applied to the HURDAT2 Atlantic hurricane intensity dataset, MEVD significantly outperforms GEV estimates of extreme hurricanes. Interestingly, the Generalized Pareto distribution used for "ordinary" hurricane intensity points to the existence of a maximum limit wind speed that is significantly smaller than corresponding physically-based estimates. Finally, we applied the MEVD approach to water levels generated by tidal fluctuations and storm surges at a set of coastal sites spanning different storm-surge regimes. MEVD yields accurate estimates of large quantiles and inferences on tail thickness (fat vs. thin) of the underlying distribution of "ordinary" surges. In summary, the MEVD approach presents a number of theoretical and practical advantages, and outperforms traditional

  2. Incorporating Wiki Technology in a Traditional Biostatistics Course: Effects on University Students’ Collaborative Learning, Approaches to Learning and Course Performance

    Directory of Open Access Journals (Sweden)

    Shirley S.M. Fong

    2017-08-01

    Full Text Available Aim/Purpose: To investigate the effectiveness of incorporating wiki technology in an under-graduate biostatistics course for improving university students’ collaborative learning, approaches to learning, and course performance. Methodology: During a three year longitudinal study, twenty-one and twenty-four undergraduate students were recruited by convenience sampling and assigned to a wiki group (2014-2015 and a control group (2013-2014 and 2015-2016, respectively. The students in the wiki group attended face-to-face lectures and used a wiki (PBworks weekly for online- group discussion, and the students in the control group had no access to the wiki and interacted face-to-face only. The students’ collaborative learning, approaches to learning, and course performance were evaluated using the Group Process Questionnaire (GPQ, Revised Study Process Questionnaire (R-SPQ-2F and course results, respectively, after testing. Findings: Multivariate analysis of variance results revealed that the R-SPQ-2F surface approach score, surface motive and strategy subscores were lower in the wiki group than in the control group (p < 0.05. The GPQ individual accountability and equal opportunity scores (components of collaboration were higher in the wiki group than in the control group (p < 0.001. No significant between-groups differences were found in any of the other outcome variables (i.e., overall course result, R-SPQ-2F deep approach score and subscores, GPQ positive interdependence score, social skills score, and composite score. Looking at the Wiki Questionnaire results, the subscale and composite scores we obtained were 31.5% to 37.7% lower than the norm. The wiki was used at a frequency of about 0.7 times per week per student. Recommendations for Practitioners: Using wiki technology in conjunction with the traditional face-to-face teaching method in a biostatistics course can enhance some aspects of undergraduate students’ collaborative learning

  3. Conjecture Mapping: An Approach to Systematic Educational Design Research

    Science.gov (United States)

    Sandoval, William

    2014-01-01

    Design research is strongly associated with the learning sciences community, and in the 2 decades since its conception it has become broadly accepted. Yet within and without the learning sciences there remains confusion about how to do design research, with most scholarship on the approach describing what it is rather than how to do it. This…

  4. Book Review: Comparative Education Research: Approaches and Methods

    Directory of Open Access Journals (Sweden)

    Noel Mcginn

    2014-10-01

    Full Text Available Book Review Comparative Education Research: Approaches and Methods (2nd edition By Mark Bray, Bob Adamson and Mark Mason (Eds. (2014, 453p ISBN: 978-988-17852-8-2, Hong Kong: Comparative Education Research Centre and Springer

  5. Interviewing for Education and Social Science Research: The Gateway Approach

    Science.gov (United States)

    Mears, Carolyn Lunsford

    2009-01-01

    This volume introduces a fresh approach to research, using strategies adapted from oral history and educational criticism to traverse the boundaries of human experience, and bring to light matters of concern to education and social science researchers. This narrator-centered method, a by-product of the author's award-winning investigation into the…

  6. Interdisciplinarity of Nano Research Fields : A Keyword Mining Approach

    NARCIS (Netherlands)

    Wang, L.; Notten, A.; Surpatean, A.

    2012-01-01

    Using a keyword mining approach, this paper explores the interdisciplinary and integrative dynamics in five nano research fields. We argue that the general trend of integration in nano research fields is converging in the long run, although the degree of this convergence depends greatly on the

  7. A sequential mixed methods research approach to investigating HIV ...

    African Journals Online (AJOL)

    Sequential mixed methods research is an effective approach for investigating complex problems, but it has not been extensively used in construction management research. In South Africa, the HIV/AIDS pandemic has seen construction management taking on a vital responsibility since the government called upon the ...

  8. Recasting Communication Theory and Research: A Cybernetic Approach.

    Science.gov (United States)

    Hill, Gary A.

    The author's main concern is to provide a research format which will supply a unitary conception of communication. The wide range of complex topics and variety of concepts embraced by communication theory and the rather disparate set of phenomena encompassed by communication research create this need for a unitary study approach capable of linking…

  9. Teaching Qualitative Research: A Successful Pilot of an Innovative Approach

    Science.gov (United States)

    Danquah, Adam N.

    2017-01-01

    This paper describes the development and delivery of an innovative approach to teaching qualitative research methods in psychology. The teaching incorporated a range of "active" pedagogical practices that it shares with other teaching in this area, but was designed in such a way as to follow the arc of a qualitative research project in…

  10. Social Pharmacy Research in Copenhagen—Maintaining a Broad Approach

    Directory of Open Access Journals (Sweden)

    Sofia Kälvemark Sporrong

    2016-02-01

    Full Text Available Social Pharmacy (SP is a multidisciplinary field to promote the adequate use of medicine. The field of SP is increasingly important due to a numbers of new trends all posing challenges to society. The SP group at the University of Copenhagen has for several years used a broad approach to SP teaching and research, often illustrated by the four levels: individual, group, organizational, and societal. In this paper the relevance of maintaining a broad approach to SP research is argued for and examples of the importance of such type of research is presented.

  11. Interdisciplinarity, Qualitative Research, and the Complex Phenomenon: Toward an Integrative Approach to Intercultural Research

    Science.gov (United States)

    Ryan, Phillip; Kurtz, Jill Sornsen; Carter, Deanne; Pester, Danielle

    2014-01-01

    This article is a collaboration by the lead faculty member in a Masters program in Intercultural Studies and students who completed the program under his aegis. This article presents the program's approach to its research course sequence, an approach involving the integration of interdisciplinary and qualitative research. The authors first provide…

  12. Researching intimacy through social media: A cross-platform approach

    OpenAIRE

    Miguel, C

    2016-01-01

    This paper aims to contribute to the understanding of how to study the way people build intimacy and manage privacy through social media interaction. It explores the research design and methodology of a research project based on a multi-sited case study composed of three different social media platforms: Badoo, CouchSurfing, and Facebook. This cross-platform approach is useful to observe how intimacy is often negotiated across different platforms. The research project focuses on the cities of...

  13. Exploring a pedagogical approach to integrating research, practice and teaching.

    Science.gov (United States)

    Newton, Jennifer M; McKenna, Lisa G; Gilmour, Carole; Fawcett, Jacqueline

    2010-01-01

    Application of evidence is accepted as an important component of clinical practice. Teaching research to undergraduate students has been reported internationally as a challenge, particularly for nurse educators. In this paper, reported is a strategy designed to enhance research learning for undergraduate midwifery students at one university, which formed part of a larger, international investigation into women's responses to caesarean birth. Following theory classes and briefings, students worked with their clinical educators in practice to interview women using existing tools, and were engaged in qualitative data analysis. A number of challenges were encountered throughout the process, both for the educators and students. However, the teaching approach provided benefits for students in learning about midwifery research. Recommended as essential is for continued development of pedagogical approaches that make research tangible for students. Furthermore, provision of support for clinical staff working with students is important for success of such approaches.

  14. Metagenomic approach reveals microbial diversity and predictive microbial metabolic pathways in Yucha, a traditional Li fermented food.

    Science.gov (United States)

    Zhang, Jiachao; Wang, Xiaoru; Huo, Dongxue; Li, Wu; Hu, Qisong; Xu, Chuanbiao; Liu, Sixin; Li, Congfa

    2016-08-31

    Yucha is a typical traditional fermented food of the Li population in the Hainan province of China, and it is made up of cooked rice and fresh fish. In the present study, metagenomic approach and culture-dependent technology were applied to describe the diversity of microbiota and identify beneficial microbes in the Yucha. At the genus level, Lactobacillus was the most abundant genus (43.82% of the total reads), followed by Lactococcus, Enterococcus, Vibrio, Weissella, Pediococcus, Enterobacter, Salinivibrio, Acinetobacter, Macrococcus, Kluyvera and Clostridium; this result was confirmed by q-PCR. PCoA based on Weighted UniFrac distances showed an apparent clustering pattern for Yucha samples from different locations, and Lactobacillus sakei, Lactobacillus saniviri and Staphylococcus sciuri represented OTUs according to the major identified markers. At the microbial functional level, it was observed that there was an enrichment of metabolic functional features, including amino acid and carbohydrate metabolism, which implied that the microbial metabolism in the Yucha samples tended to be vigorous. Accordingly, we further investigated the correlation between the predominant microbes and metabolic functional features. Thirteen species of Lactobacillus (147 strains) were isolated, and Lactobacillus plantarum (60 isolates) and Lactobacillus pentosus (34 isolates) were isolated from every sample.

  15. Drought assessment in the Dongliao River basin: traditional approaches vs. generalized drought assessment index based on water resources systems

    Science.gov (United States)

    Weng, B. S.; Yan, D. H.; Wang, H.; Liu, J. H.; Yang, Z. Y.; Qin, T. L.; Yin, J.

    2015-08-01

    Drought is firstly a resource issue, and with its development it evolves into a disaster issue. Drought events usually occur in a determinate but a random manner. Drought has become one of the major factors to affect sustainable socioeconomic development. In this paper, we propose the generalized drought assessment index (GDAI) based on water resources systems for assessing drought events. The GDAI considers water supply and water demand using a distributed hydrological model. We demonstrate the use of the proposed index in the Dongliao River basin in northeastern China. The results simulated by the GDAI are compared to observed drought disaster records in the Dongliao River basin. In addition, the temporal distribution of drought events and the spatial distribution of drought frequency from the GDAI are compared with the traditional approaches in general (i.e., standard precipitation index, Palmer drought severity index and rate of water deficit index). Then, generalized drought times, generalized drought duration, and generalized drought severity were calculated by theory of runs. Application of said runs at various drought levels (i.e., mild drought, moderate drought, severe drought, and extreme drought) during the period 1960-2010 shows that the centers of gravity of them all distribute in the middle reaches of Dongliao River basin, and change with time. The proposed methodology may help water managers in water-stressed regions to quantify the impact of drought, and consequently, to make decisions for coping with drought.

  16. [Research on the application of grey system theory in the pattern recognition for chromatographic fingerprints of traditional Chinese medicine].

    Science.gov (United States)

    Wei, Hang; Lin, Li; Zhang, Yuan; Wang, Lianjing; Chen, Qinqun

    2013-02-01

    A model based on grey system theory was proposed for pattern recognition in chromatographic fingerprints (CF) of traditional Chinese medicine (TCM). The grey relational grade among the data series of each testing CF and the ideal CF was obtained by entropy and norm respectively, then the principle of "maximal matching degree" was introduced to make judgments, so as to achieve the purpose of variety identification and quality evaluation. A satisfactory result in the high performance liquid chromatographic (HPLC) analysis of 56 batches of different varieties of Exocarpium Citrus Grandis was achieved with this model. The errors in the chromatographic fingerprint analysis caused by traditional similarity method or grey correlation method were overcome, as the samples of Citrus grandis 'Tomentosa' and Citrus grandis (L.) Osbeck were correctly distinguished in the experiment. Furthermore in the study on the variety identification of Citrus grandis 'Tomentosa', the recognition rates were up to 92.85%, although the types and the contents of the chemical compositions of the samples were very close. At the same time, the model had the merits of low computation complexity and easy operation by computer programming. The research indicated that the grey system theory has good applicability to pattern recognition in the chromatographic fingerprints of TCM.

  17. Changing the lens: widening the approach to primary care research.

    Science.gov (United States)

    Checkland, Kath

    2003-10-01

    After years of being shielded from most of the managerial and organisational changes in health care, primary care is going through a period of change in many countries. Much of the research that has been done in primary care, in common with that in secondary care, puts at the centre of its methodology the concept of professionalism. However, there are other ways of theorising medical work, and using a wider range of theoretical 'lenses' when planning research into the impact of change will enhance and enrich that research. Viewing primary care physicians as 'workers', concerned, like other workers, with constructing understanding of what they do that helps them cope with pressures and uncertainties, shifts the focus of research questions away from issues of professional status towards the practical ways in which they deal with change in their local contexts. Research using this theoretical approach may be able to explain phenomena that other, more broad-brush approaches cannot.

  18. [Textual research on relationship between traditional Chinese medicine and medical prescriptions in the Sanskrit formulary Bower Manuscript excavated in Xinjiang].

    Science.gov (United States)

    Wang, Xingyi

    2015-05-01

    This paper introduces the Bower Manuscript in Sanskrit written on birch bark excavated in Xinjiang, which was bought in Kuqa by a British India army lieutenant Bower, hence its title. Then, it was researched, annotated, and published in 7 volumes by a German British lieutenant and orientalist Honer. The first three volumes are devoted to medical prescriptions. It is first verified that its "Dazi Xiangye San" is the "Dujuan Dachen San" in Tibetan medicine. By comparing it with other traditional medical systems, such as Chinese, Tibetan, Mongolian, and Uyghur medical systems, we found that Bower Manuscript is closer to Tibetan medicine and Mongolian medicine, while it has less relation with Chinese medicine and Uyghur medicine. However, it also exerts some influence on TCM.

  19. The client-centred approach as experienced by male neurological rehabilitation clients in occupational therapy. A qualitative study based on a grounded theory tradition.

    Science.gov (United States)

    Van de Velde, Dominique; Devisch, Ignaas; De Vriendt, Patricia

    2016-08-01

    Purpose To explore the perspectives of male clients in a neurological rehabilitation setting with regard to the occupational therapy they have received and the client-centred approach. Method This study involved a qualitative research design based on the grounded theory tradition. Individual in-depth interviews were used to collect data. Data were analysed using a constant comparative method. Seven male participants from an inpatient neurological setting were included using a theoretical sampling technique. Results Three themes emerged to describe the approach of the therapists to client-centred practice: (a) a shared biomedical focus as the start of the rehabilitation process, (b) the un-simultaneous shift from a biomedical towards a psycho-social focus and (c) formal versus informal nature of gathering client information. Conclusion A client-centred approach entails a shift from the therapist focussing on recovery from the short-term neurological issues towards the long-term consequences of the disease. According to the client, this shift in reasoning must occur at a specific and highly subjective moment during the rehabilitation process. Identifying this moment could strengthen the client-centred approach. Implications for Rehabilitation Client-centred practice entails a shift from recovering the short-term neurological issues towards the long-term psycho-social consequences of the disease. To be effective in client-centred practice, the clients expect from the professional to be an authority with regard to biomedical issues and to be partner with regard to psycho-social issues. Client-centred practice is most likely to be successful when client is susceptible to discuss his psycho-social issues and finding this moment is a challenge for the professional. Using formal methods for goal setting do not necessarily cover all the information needed for a client-centred therapy programme. Rather, using informal methods could lead to a more valid image of the client.

  20. Action Research – A New Approach for Environmental RD

    Directory of Open Access Journals (Sweden)

    Danubianu Mirela

    2015-05-01

    Full Text Available High efficiency research, development and innovation (RD&I constitute an answer to the ever growing importance that EU states give to knowledge-based development (a central idea in the Europe 2020 Strategy, directed toward finding comprehensive solutions to concerns connected to the Europe’s resource depletion, energy future, climate changes, etc. The "Action Research" paradigm appeared in the late 1940s but its systematic application is the attribute of recent years. It keeps researchers in the real world, requires teamwork, collaboration with communities and other stakeholders. Action Research is especially suitable in projects for reducing anthropic footprint / environmental aggression and in waste management. In essence, Action Research (for the first time systematically applied in Romania is the research approach that lets the problem studied to conduct the analysis and generate appropriate solutions; it constitutes a flexible, versatile technique to generate new knowledge through iterative interaction with the domain studied - namely the environment - researchers and communities.

  1. Strategic approach to outsourcing the research and development function

    OpenAIRE

    Firend, A.R

    2010-01-01

    This paper proposes an approach for outsourcing the R&D function. This model is to serve as a strategic approach to outsourcing that considers number of elements with strategic competitive advantage as an ultimate objective. This paper suggest that outsourcing research and development should be planed and conducted from a strategic standpoint and have positive impact on organizational competitive position by incorporating it into the overall\\ud strategy of the organization to reduce the numbe...

  2. Revisiting regional flood frequency analysis in Slovakia: the region-of-influence method vs. traditional regional approaches

    Science.gov (United States)

    Gaál, Ladislav; Kohnová, Silvia; Szolgay, Ján.

    2010-05-01

    root mean square error of data from Monte Carlo simulations. The analysis is based on the annual peak discharges from 168 small and mid-sized catchments from Slovakia. The study is supported by the Grant Agency of AS CR under project B300420801; the Slovak Research and Development Agency under the contract No. APVV-0443-07 and the Slovak VEGA Grant Agency under the project No. 1/0103/10. Burn, D.H., 1990: Evaluation of regional flood frequency analysis with a region of influence approach. Water Resources Research, 26(10), 2257-2265. Hosking, J.R.M., Wallis, J.R., 1997: Regional frequency analysis: an approach based on L-moments. Cambridge University Press, Cambridge. Lu, L.-H., Stedinger, J.R., 1992: Sampling variance of normalized GEV/PWM quantile estimators and a regional homogeneity test. Journal of Hydrology, 138(1-2), 223-245.

  3. Undergraduate Biology Lab Courses: Comparing the Impact of Traditionally Based "Cookbook" and Authentic Research-Based Courses on Student Lab Experiences

    Science.gov (United States)

    Brownell, Sara E.; Kloser, Matthew J.; Fukami, Tadishi; Shavelson, Rich

    2012-01-01

    Over the past decade, several reports have recommended a shift in undergraduate biology laboratory courses from traditionally structured, often described as "cookbook," to authentic research-based experiences. This study compares a cookbook-type laboratory course to a research-based undergraduate biology laboratory course at a Research 1…

  4. Perceptions of Faculty toward Integrating Technology in Undergraduate Higher Education Traditional Classrooms at Research-Focused Regional Universities in South Texas

    Science.gov (United States)

    Shipman, Cheri Deann

    2017-01-01

    This qualitative study examined the perceptions of faculty members who use technology in undergraduate higher education traditional classrooms in research-focused regional universities in South Texas. Faculty members at research-focused regional universities are expected to divide time judiciously into three major areas: research, service, and…

  5. Translational research-the need of a new bioethics approach.

    Science.gov (United States)

    Hostiuc, Sorin; Moldoveanu, Alin; Dascălu, Maria-Iuliana; Unnthorsson, Runar; Jóhannesson, Ómar I; Marcus, Ioan

    2016-01-15

    Translational research tries to apply findings from basic science to enhance human health and well-being. Many phases of the translational research may include non-medical tasks (information technology, engineering, nanotechnology, biochemistry, animal research, economy, sociology, psychology, politics, and so on). Using common bioethics principles to these areas might sometimes be not feasible, or even impossible. However, the whole process must respect some fundamental, moral principles. The purpose of this paper is to argument the need for a different approach to the morality in translational bioethics, and to suggest some directions that might be followed when constructing such a bioethics. We will show that a new approach is needed and present a few ethical issues that are specific to the translational research.

  6. Integrating Human Factors Engineering and Information Processing Approaches to Facilitate Evaluations in Criminal Justice Technology Research.

    Science.gov (United States)

    Salvemini, Anthony V; Piza, Eric L; Carter, Jeremy G; Grommon, Eric L; Merritt, Nancy

    2015-06-01

    Evaluations are routinely conducted by government agencies and research organizations to assess the effectiveness of technology in criminal justice. Interdisciplinary research methods are salient to this effort. Technology evaluations are faced with a number of challenges including (1) the need to facilitate effective communication between social science researchers, technology specialists, and practitioners, (2) the need to better understand procedural and contextual aspects of a given technology, and (3) the need to generate findings that can be readily used for decision making and policy recommendations. Process and outcome evaluations of technology can be enhanced by integrating concepts from human factors engineering and information processing. This systemic approach, which focuses on the interaction between humans, technology, and information, enables researchers to better assess how a given technology is used in practice. Examples are drawn from complex technologies currently deployed within the criminal justice system where traditional evaluations have primarily focused on outcome metrics. Although this evidence-based approach has significant value, it is vulnerable to fully account for human and structural complexities that compose technology operations. Guiding principles for technology evaluations are described for identifying and defining key study metrics, facilitating communication within an interdisciplinary research team, and for understanding the interaction between users, technology, and information. The approach posited here can also enable researchers to better assess factors that may facilitate or degrade the operational impact of the technology and answer fundamental questions concerning whether the technology works as intended, at what level, and cost. © The Author(s) 2015.

  7. Creative Approaches to Teaching Graduate Research Methods Workshops

    OpenAIRE

    Peter Reilly

    2017-01-01

    Engagement and deeper learning were enhanced by developing several innovative teaching strategies delivered in Research Methods workshops to Graduate Business Students.  Focusing primarily on students adopting a creative approach to formulating a valid research question for undertaking a dissertation successfully. These techniques are applicable to most subject domains to ensure student engagement.  Addressing the various multiple intelligences and learning styles existing within groups while...

  8. Analysis of bacterial community during the fermentation of pulque, a traditional Mexican alcoholic beverage, using a polyphasic approach.

    Science.gov (United States)

    Escalante, Adelfo; Giles-Gómez, Martha; Hernández, Georgina; Córdova-Aguilar, María Soledad; López-Munguía, Agustín; Gosset, Guillermo; Bolívar, Francisco

    2008-05-31

    In this study, the characterization of the bacterial community present during the fermentation of pulque, a traditional Mexican alcoholic beverage from maguey (Agave), was determined for the first time by a polyphasic approach in which both culture and non-culture dependent methods were utilized. The work included the isolation of lactic acid bacteria (LAB), aerobic mesophiles, and 16S rDNA clone libraries from total DNA extracted from the maguey sap (aguamiel) used as substrate, after inoculation with a sample of previously produced pulque and followed by 6-h fermentation. Microbiological diversity results were correlated with fermentation process parameters such as sucrose, glucose, fructose and fermentation product concentrations. In addition, medium rheological behavior analysis and scanning electron microscopy in aguamiel and during pulque fermentation were also performed. Our results showed that both culture and non-culture dependent approaches allowed the detection of several new and previously reported species within the alpha-, gamma-Proteobacteria and Firmicutes. Bacteria diversity in aguamiel was composed by the heterofermentative Leuconostoc citreum, L. mesenteroides, L. kimchi, the gamma-Proteobacteria Erwinia rhapontici, Enterobacter spp. and Acinetobacter radioresistens. Inoculation with previously fermented pulque incorporated to the system microbiota, homofermentative lactobacilli related to Lactobacillus acidophilus, several alpha-Proteobacteria such as Zymomonas mobilis and Acetobacter malorum, other gamma-Proteobacteria and an important amount of yeasts, creating a starting metabolic diversity composed by homofermentative and heterofermentative LAB, acetic and ethanol producing microorganisms. At the end of the fermentation process, the bacterial diversity was mainly composed by the homofermentative Lactobacillus acidophilus, the heterofermentative L. mesenteroides, Lactococcus lactis subsp. lactis and the alpha-Proteobacteria A. malorum. After

  9. [Research progress on standardization study of NIR spectroscopy based method for quality control of traditional Chinese medicine].

    Science.gov (United States)

    Li, Wen-Long; Qu, Hai-Bin

    2016-10-01

    In recent years, the near infrared (NIR) spectroscopy has gained wide acceptance within the quantitative analysis of traditional Chinese medicine (TCM). However, the lack of technical standards is the bottleneck problem in this process. To address this issue, standardization study of the NIR spectroscopy based method for the quantitative analysis of TCM is needed, in which the specific characteristics of TCM should be given full considerations. The main research contents include:the scope definition for the application of NIR spectroscopy in the TCM quantitative analysis field, the selection criteria for the sample pretreatment and spectral acquisition conditions, the rules for the model optimization and evaluation, and the regulations for the model update and transfer. In this paper, some foreign studies in the agricultural areas are reviewed for reference. Different chemometrics methods reported in the literature are investigated and compared systematically. This research is important actual significance to the theoretical development of NIR spectroscopy analytical techniques, and will effectively promote the application of the technology in the TCM industry. Furthermore, it is beneficial to improve the technical level of TCM quality control, and can also be used as references to achieve similar purposes for other natural products. Copyright© by the Chinese Pharmaceutical Association.

  10. Partnering with patients in translational oncology research: ethical approach.

    Science.gov (United States)

    Mamzer, Marie-France; Duchange, Nathalie; Darquy, Sylviane; Marvanne, Patrice; Rambaud, Claude; Marsico, Giovanna; Cerisey, Catherine; Scotté, Florian; Burgun, Anita; Badoual, Cécile; Laurent-Puig, Pierre; Hervé, Christian

    2017-04-08

    The research program CARPEM (cancer research and personalized medicine) brings together the expertise of researchers and hospital-based oncologists to develop translational research in the context of personalized or "precision" medicine for cancer. There is recognition that patient involvement can help to take into account their needs and priorities in the development of this emerging practice but there is currently no consensus about how this can be achieved. In this study, we developed an empirical ethical research action aiming to improve patient representatives' involvement in the development of the translational research program together with health professionals. The aim is to promote common understanding and sharing of knowledge between all parties and to establish a long-term partnership integrating patient's expectations. Two distinct committees were settled in CARPEM: an "Expert Committee", gathering healthcare and research professionals, and a "Patient Committee", gathering patients and patient representatives. A multidisciplinary team trained in medical ethics research ensured communication between the two committees as well as analysis of discussions, minutes and outputs from all stakeholders. The results highlight the efficiency of the transfer of knowledge between interested parties. Patient representatives and professionals were able to identify new ethical challenges and co-elaborate new procedures to gather information and consent forms for adapting to practices and recommendations developed during the process. Moreover, included patient representatives became full partners and participated in the transfer of knowledge to the public via conferences and publications. Empirical ethical research based on a patient-centered approach could help in establishing a fair model for coordination and support actions during cancer research, striking a balance between the regulatory framework, researcher needs and patient expectations. Our approach addresses

  11. International health research monitoring: exploring a scientific and a cooperative approach using participatory action research

    OpenAIRE

    Chantler, Tracey; Cheah, Phaik Yeong; Miiro, George; Hantrakum, Viriya; Nanvubya, Annet; Ayuo, Elizabeth; Kivaya, Esther; Kidola, Jeremiah; Kaleebu, Pontiano; Parker, Michael; Njuguna, Patricia; Ashley, Elizabeth; Guerin, Philippe J; Lang, Trudie

    2014-01-01

    Objectives To evaluate and determine the value of monitoring models developed by the Mahidol Oxford Tropical Research Unit and the East African Consortium for Clinical Research, consider how this can be measured and explore monitors’ and investigators’ experiences of and views about the nature, purpose and practice of monitoring. Research design A case study approach was used within the context of participatory action research because one of the aims was to guide and improve practice. 34 inte...

  12. Managing Cybersecurity Research and Experimental Development: The REVO Approach

    Directory of Open Access Journals (Sweden)

    Dan Craigen

    2013-07-01

    Full Text Available We present a systematic approach for managing a research and experimental development cybersecurity program that must be responsive to continuously evolving cybersecurity, and other, operational concerns. The approach will be of interest to research-program managers, academe, corporate leads, government leads, chief information officers, chief technology officers, and social and technology policy analysts. The approach is compatible with international standards and procedures published by the Organisation for Economic Co-operation and Development (OECD and the Treasury Board of Canada Secretariat (TBS. The key benefits of the approach are the following: i the breadth of the overall (cybersecurity space is described; ii depth statements about specific (cybersecurity challenges are articulated and mapped to the breadth of the problem; iii specific (cybersecurity initiatives that have been resourced through funding or personnel are tracked and linked to specific challenges; and iv progress is assessed through key performance indicators. Although we present examples from cybersecurity, the method may be transferred to other domains. We have found the approach to be rigorous yet adaptive to change; it challenges an organization to be explicit about the nature of its research and experimental development in a manner that fosters alignment with evolving business priorities, knowledge transfer, and partner engagement.

  13. Multilevel approach to mentoring in the Research Experiences for Undergraduates programs

    Science.gov (United States)

    Bonine, K. E.; Dontsova, K.; Pavao-Zuckerman, M.; Paavo, B.; Hogan, D.; Oberg, E.; Gay, J.

    2015-12-01

    This presentation focuses on different types of mentoring for students participating in Research Experiences for Undergraduates programs with examples, including some new approaches, from The Environmental and Earth Systems Research Experiences for Undergraduates Program at Biosphere 2. While traditional faculty mentors play essential role in students' development as researchers and professionals, other formal and informal mentoring can be important component of the REU program and student experiences. Students receive mentoring from program directors, coordinators, and on site undergraduate advisors. While working on their research projects, REU students receive essential support and mentoring from undergraduate and graduate students and postdoctoral scientists in the research groups of their primary mentors. Cohort living and group activities give multiple opportunities for peer mentoring where each student brings their own strengths and experiences to the group. Biosphere 2 REU program puts strong emphasis on teaching students to effectively communicate their research to public. In order to help REUs learn needed skills the outreach personnel at Biosphere 2 mentor and advise students both in groups and individually, in lecture format and by personal example, on best outreach approaches in general and on individual outreach projects students develop. To further enhance and strengthen outreach mentoring we used a novel approach of blending cohort of REU students with the Cal Poly STAR (STEM Teacher And Researcher) Program fellows, future K-12 STEM teachers who are gaining research experience at Biosphere 2. STAR fellows live together with the REU students and participate with them in professional development activities, as well as perform research side by side. Educational background and experiences gives these students a different view and better preparation and tools to effectively communicate and adapt science to lay audiences, a challenge commonly facing

  14. Constructive Synergy in Design Science Research: A Comparative Analysis of Design Science Research and the Constructive Research Approach

    DEFF Research Database (Denmark)

    Piirainen, Kalle; Gonzalez, Rafael A.

    2014-01-01

    Information systems research is focused on creating knowledge which can be applied in organizations. Design science research, which specifically aims at applying existing knowledge to solve interesting and relevant business problems, has been steadily gaining support in information systems research....... However, design science research is not the only design-oriented research framework available. Accordingly, this raises the question of whether there is something to learn between the different approaches. This paper contributes to answering this question by comparing design science research...... with the constructive research approach. The conclusion is that the two approaches are similar and compatible, save for details in practical requirements and partly underlying philosophical assumptions. The main finding that arises from the comparison is, however, that there is a potential problem in claiming knowledge...

  15. Constructive Synergy in Design Science Research: A Comparative Analysis of Design Science Research and the Constructive Research Approach

    DEFF Research Database (Denmark)

    Piirainen, Kalle; Gonzalez, Rafael A.

    2014-01-01

    with the constructive research approach. The conclusion is that the two approaches are similar and compatible, save for details in practical requirements and partly underlying philosophical assumptions. The main finding that arises from the comparison is, however, that there is a potential problem in claiming knowledge......Information systems research is focused on creating knowledge which can be applied in organizations. Design science research, which specifically aims at applying existing knowledge to solve interesting and relevant business problems, has been steadily gaining support in information systems research....... However, design science research is not the only design-oriented research framework available. Accordingly, this raises the question of whether there is something to learn between the different approaches. This paper contributes to answering this question by comparing design science research...

  16. Experiential Approach to Teaching Statistics and Research Methods ...

    African Journals Online (AJOL)

    Statistics and research methods are among the more demanding topics for students of education to master at both the undergraduate and postgraduate levels. It is our conviction that teaching these topics should be combined with real practical experiences. We discuss an experiential teaching/ learning approach that ...

  17. A techno-managerial approach in food quality management research

    NARCIS (Netherlands)

    Luning, P.A.; Marcelis, W.J.

    2006-01-01

    In this article it is discussed that food quality management issues are much more complex than often assumed and that it requires a specific research approach. It is argued that food quality management deals with dynamic and complex food systems and people systems involved in realising food quality.

  18. Case Studies Approach in Tourism Destination Branding Research

    Directory of Open Access Journals (Sweden)

    Adeyinka-Ojo S.F.

    2014-01-01

    Full Text Available A review of literature indicates that there are different types of qualitative research methods such as action research, content analysis, ethnography, grounded theory, historical analysis, phenomenology and case study. However, which approach is to be used depends on several factors such as the nature and objectives of the research. The aim of this paper is to focus on the research methodology aspects of applying case study as a research approach and its relevance in tourism destination branding research specifically on a single case study (SCS context. There are arguments that the SCS is a weak research strategy. Some of the potentials or shortcomings highlighted in the literature include the primitive nature of SCS, flexibility of sample technique, data collection method and data analysis. Others include lack of rigour, reliability, validity, credibility of findings and generalisation. This paper has adopted content analysis of the literature on tourism destination branding. Findings indicate that the quality of SCS can be verified using specific case study tactics for four design tests such as validity (construct, internal and external; and reliability using the case study protocol. Theoretical implication suggests that SCS is an empirical enquiry use to understand complex phenomena and favoured by practitioners.

  19. Setting research priorities by applying the combined approach matrix.

    Science.gov (United States)

    Ghaffar, Abdul

    2009-04-01

    Priority setting in health research is a dynamic process. Different organizations and institutes have been working in the field of research priority setting for many years. In 1999 the Global Forum for Health Research presented a research priority setting tool called the Combined Approach Matrix or CAM. Since its development, the CAM has been successfully applied to set research priorities for diseases, conditions and programmes at global, regional and national levels. This paper briefly explains the CAM methodology and how it could be applied in different settings, giving examples and describing challenges encountered in the process of setting research priorities and providing recommendations for further work in this field. The construct and design of the CAM is explained along with different steps needed, including planning and organization of a priority-setting exercise and how it could be applied in different settings. The application of the CAM are described by using three examples. The first concerns setting research priorities for a global programme, the second describes application at the country level and the third setting research priorities for diseases. Effective application of the CAM in different and diverse environments proves its utility as a tool for setting research priorities. Potential challenges encountered in the process of research priority setting are discussed and some recommendations for further work in this field are provided.

  20. Practice-Based Interdisciplinary Approach and Environmental Research

    Directory of Open Access Journals (Sweden)

    Ranjan Kumar Datta

    2017-03-01

    Full Text Available Interdisciplinary researchers and educators, as community members, creators of knowledge, and environmental activists and practitioners, have a responsibility to build a bridge between community practice, academic scholarship, and professional contributions aimed at establishing environmental sustainability. In this paper, I focus on an undervalued area of environmental politics, practices, and often unarticulated assumptions which underlie human–environmental relations. This article challenges interdisciplinary studies that are not connected with practice by reconfiguring the meaning of a community-based, interdisciplinary approach. Drawing from works by Foucault, Latour, and Haraway, this paper first shows how to reconfigure the meaning of an interdisciplinary approach. Second, using Bourdieu and Brightman’s ethnographic studies as a framework, the paper situates practice as central to our efforts to deconstruct and replace current interdisciplinary initiatives with a practice-based approach. Through a practice-based interdisciplinary approach (PIA, environmental educators and researchers gain an awareness of and learn to make an investment in sustainable communities. As teams of environmental researchers practising in the local community, they are meaningfully involved with the community, with each other, and with the environment.

  1. Introduction to Safety Analysis Approach for Research Reactors

    International Nuclear Information System (INIS)

    Park, Suki

    2016-01-01

    The research reactors have a wide variety in terms of thermal powers, coolants, moderators, reflectors, fuels, reactor tanks and pools, flow direction in the core, and the operating pressure and temperature of the cooling system. Around 110 research reactors have a thermal power greater than 1 MW. This paper introduces a general approach to safety analysis for research reactors and deals with the experience of safety analysis on a 10 MW research reactor with an open-pool and open-tank reactor and a downward flow in the reactor core during normal operation. The general approach to safety analysis for research reactors is described and the design features of a typical open-pool and open-tank type reactor are discussed. The representative events expected in research reactors are investigated. The reactor responses and the thermal hydraulic behavior to the events are presented and discussed. From the minimum CHFR and the maximum fuel temperature calculated, it is ensured that the fuel is not damaged in the step insertion of reactivity by 1.8 mk and the failure of all primary pumps for the reactor with a 10 MW thermal power and downward core flow

  2. Uniting Resilience Research and Practice With an Inequalities Approach

    Directory of Open Access Journals (Sweden)

    Angie Hart

    2016-12-01

    Full Text Available The concept of resilience has evolved, from an individual-level characteristic to a wider ecological notion that takes into account broader person–environment interactions, generating an increased interest in health and well-being research, practice and policy. At the same time, the research and policy-based attempts to build resilience are increasingly under attack for responsibilizing individuals and maintaining, rather than challenging, the inequitable structure of society. When adversities faced by children and young people result from embedded inequality and social disadvantage, resilience-based knowledge has the potential to influence the wider adversity context. Therefore, it is vital that conceptualizations of resilience encompass this potential for marginalized people to challenge and transform aspects of their adversity, without holding them responsible for the barriers they face. This article outlines and provides examples from an approach that we are taking in our research and practice, which we have called Boingboing resilience. We argue that it is possible to bring resilience research and practice together with a social justice approach, giving equal and simultaneous attention to individuals and to the wider system. To achieve this goal, we suggest future research should have a co-produced and inclusive research design that overcomes the dilemma of agency and responsibility, contains a socially transformative element, and has the potential to empower children, young people, and families.

  3. The ethics of pharmaceutical research funding: a social organization approach.

    Science.gov (United States)

    Gray, Garry C

    2013-01-01

    This paper advances a social organization approach to examining unethical behavior. While unethical behaviors may stem in part from failures in individual morality or psychological blind spots, they are both generated and performed through social interactions among individuals and groups. To illustrate the value of a social organization approach, a case study of a medical school professor's first experience with pharmaceutical-company-sponsored research is provided in order to examine how funding arrangements can constrain research integrity. The case illustrates three significant ways that institutional corruption can occur in the research process. First, conflicts of norms between pharmaceutical companies, universities, and affiliated teaching hospitals can result in compromises and self-censorship. Second, normal behavior is shaped through routine interactions. Unethical behaviors can be (or can become) normal behaviors when they are produced and reproduced through a network of social interactions. Third, funding arrangements can create networks of dependency that structurally distort the independence of the academic researcher in favor of the funder's interests. More broadly, the case study demonstrates how the social organization approach deepens our understanding of the practice of ethics. © 2013 American Society of Law, Medicine & Ethics, Inc.

  4. Development of Digital MMIS for Research Reactors: Graded Approaches

    International Nuclear Information System (INIS)

    Khalil ur, Rahman; Shin, Jin Soo; Heo, Gyun Young; Son, Han Seong; Kim, Young Ki; Park, Jae Kwan; Seo, Sang Mun; Kim, Yong Jun

    2012-01-01

    Though research reactors are small in size yet they are important in terms of industrial applications and R and D, educational purposes. Keeping the eye on its importance, Korean government has intention to upgrade and extend this industry. Presently, Korea is operating only HANARO at Korea Atomic Energy Research Institute (KAERI) and AGN-201K at Kyung Hee University (KHU), which are not sufficient to meet the current requirements of research and education. In addition, we need self-sufficiency in design and selfreliance in design and operation, as we are installing research reactors in domestic as well as foreign territories for instance Jordan. Based on these demands, KAERI and universities initiated a 5 year research project since December 2011 collaboratly, for the deep study of reactor core, thermal hydraulics, materials and instrumentation and control (I and C). This particular study is being carried out to develop highly reliable advanced digital I and C systems using a grading approach. It is worth mentioning that next generation research reactor should be equipped with advance state of the art digital I and C for safe and reliable operation and impermeable cyber security system that is needed to be devised. Moreover, human error is one of important area which should be linked with I and C in terms of Man Machine Interface System (MMIS) and development of I and C should cover human factor engineering. Presently, the digital I and C and MMIS are well developed for commercial power stations whereas such level of development does not exist for research reactors in Korea. Since the functional and safety requirements of research reactors are not so strict as commercial power plants, the design of digital I and C systems for research reactors seems to be graded based on the stringency of regulatory requirements. This paper was motivated for the introduction of those missions, so it is going to describe the general overview of digital I and C systems, the graded

  5. Development of Digital MMIS for Research Reactors: Graded Approaches

    Energy Technology Data Exchange (ETDEWEB)

    Khalil ur, Rahman; Shin, Jin Soo; Heo, Gyun Young [Kyunghee University, Yongin (Korea, Republic of); Son, Han Seong [Joongbu University, Geumsan (Korea, Republic of); Kim, Young Ki; Park, Jae Kwan; Seo, Sang Mun; Kim, Yong Jun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-05-15

    Though research reactors are small in size yet they are important in terms of industrial applications and R and D, educational purposes. Keeping the eye on its importance, Korean government has intention to upgrade and extend this industry. Presently, Korea is operating only HANARO at Korea Atomic Energy Research Institute (KAERI) and AGN-201K at Kyung Hee University (KHU), which are not sufficient to meet the current requirements of research and education. In addition, we need self-sufficiency in design and selfreliance in design and operation, as we are installing research reactors in domestic as well as foreign territories for instance Jordan. Based on these demands, KAERI and universities initiated a 5 year research project since December 2011 collaboratly, for the deep study of reactor core, thermal hydraulics, materials and instrumentation and control (I and C). This particular study is being carried out to develop highly reliable advanced digital I and C systems using a grading approach. It is worth mentioning that next generation research reactor should be equipped with advance state of the art digital I and C for safe and reliable operation and impermeable cyber security system that is needed to be devised. Moreover, human error is one of important area which should be linked with I and C in terms of Man Machine Interface System (MMIS) and development of I and C should cover human factor engineering. Presently, the digital I and C and MMIS are well developed for commercial power stations whereas such level of development does not exist for research reactors in Korea. Since the functional and safety requirements of research reactors are not so strict as commercial power plants, the design of digital I and C systems for research reactors seems to be graded based on the stringency of regulatory requirements. This paper was motivated for the introduction of those missions, so it is going to describe the general overview of digital I and C systems, the graded

  6. Recent progress of research on medicinal mushrooms, foods, and other herbal products used in traditional Chinese medicine

    Directory of Open Access Journals (Sweden)

    Kuo-Hsiung Lee

    2012-04-01

    Full Text Available This article will review selected herbal products used in traditional Chinese medicine, including medicinal mushrooms (巴西蘑菇 bā xī mó gū; Agaricus blazei, 雲芝 yún zhī; Coriolus versicolor, 靈芝 líng zhī; Ganoderma lucidum, 香蕈 xiāng xùn; shiitake, Lentinus edodes, 牛樟芝 niú zhāng zhī; Taiwanofungus camphoratus, Cordyceps (冬蟲夏草 dōng chóng xià cǎo, pomegranate (石榴 shí liú; Granati Fructus, green tea (綠茶 lǜ chá; Theae Folium Non Fermentatum, garlic (大蒜 dà suàn; Allii Sativi Bulbus, turmeric (薑黃 jiāng huáng; Curcumae Longae Rhizoma, and Artemisiae Annuae Herba (青蒿 qīng hāo; sweet wormwood. Many of the discussed herbal products have gained popularity in their uses as dietary supplements for health benefits. The review will focus on the active constituents of the herbs and their bioactivities, with emphasis on the most recent progress in research for the period of 2003 to 2011.

  7. Conservation and re-development of sade traditional kampong at Rambitan village with local approach and cultural landscape

    Science.gov (United States)

    Harapan Siregar, Andi

    2018-03-01

    Sade Kampong is one of the traditional kampongs in Indonesia, which located at Rambitan Village, Lombok. Lombok has been developed for tourism activity since years ago. The Lombok Province Government has identified Tourism as one of the key drives for the economic development. Hotel resort and others hospitalities buildings have been developed to all of the areas. Nowadays, the development of Sade Cultural Kampong will therefore open up new and demand oriented products (only focus on traditional woven of Sasak). Sade Kampong should be developed as a tourism destination with appreciated and developed its heritage and traditions with sustainability concepts (with the focus on social, economic, and environmental). This paper will elaborate some local potential Sade Kampong, such as architecture, culture, and landscape as a local potential for developing a new tourism destination.

  8. Creative Approaches to Teaching Graduate Research Methods Workshops

    Directory of Open Access Journals (Sweden)

    Peter Reilly

    2017-06-01

    Full Text Available Engagement and deeper learning were enhanced by developing several innovative teaching strategies delivered in Research Methods workshops to Graduate Business Students.  Focusing primarily on students adopting a creative approach to formulating a valid research question for undertaking a dissertation successfully. These techniques are applicable to most subject domains to ensure student engagement.  Addressing the various multiple intelligences and learning styles existing within groups while ensuring these sessions are student centred and conducive to a collaborative learning environment.  Blogs, interactive tutorials, online videos, games and posters, are used to develop student’s cognitive and metacognitive abilities.  Using novelty images appeals to a groups’ intellectual curiosity, acting as an interpretive device to explain  the value of adopting a holistic rather than analytic approach towards a topic.

  9. Ecosystem approach to inland fisheries: research needs and implementation strategies

    Science.gov (United States)

    Beard, T. Douglas; Arlinghaus, Robert; Cooke, Steven J.; McIntyre, Peter B.; De Silva, Sena; Bartley, Devin M.; Cowx, Ian G.

    2011-01-01

    Inland fisheries are a vital component in the livelihoods and food security of people throughout the world, as well as contributing huge recreational and economic benefits. These valuable assets are jeopardized by lack of research-based understanding of the impacts of fisheries on inland ecosystems, and similarly the impact of human activities associated with inland waters on fisheries and aquatic biodiversity. To explore this topic, an international workshop was organized in order to examine strategies to incorporate fisheries into ecosystem approaches for management of inland waters. To achieve this goal, a new research agenda is needed that focuses on: quantifying the ecosystem services provided by fresh waters; quantifying the economic, social and nutritional benefits of inland fisheries; improving assessments designed to evaluate fisheries exploitation potential; and examining feedbacks between fisheries, ecosystem productivity and aquatic biodiversity. Accomplishing these objectives will require merging natural and social science approaches to address coupled social–ecological system dynamics.

  10. Comparing Case Study and Ethnography as Qualitative Research Approaches

    OpenAIRE

    Suryani, Anne

    2008-01-01

    Abstract: This article reviews several differences between case study and ethnography in terms of definitions, characteristics, strengths and limitations. It provides current information by comparing these approaches from various social researchers’ perspectives. Although each method has strong points, they both have differences in conducting observation and interview as data collection techniques; choosing the length of time of data gathering and reporting details of a particular reality....

  11. Comparing Case Study and Ethnography as Qualitative Research Approaches

    Directory of Open Access Journals (Sweden)

    Anne Suryani

    2013-12-01

    Full Text Available Abstract: This article reviews several differences between case study and ethnography in terms of definitions, characteristics, strengths and limitations. It provides current information by comparing these approaches from various social researchers’ perspectives. Although each method has strong points, they both have differences in conducting observation and interview as data collection techniques; choosing the length of time of data gathering and reporting details of a particular reality.

  12. Beyond Traditional Newspaper Advertisement: Leveraging Facebook-Targeted Advertisement to Recruit Long-Term Smokers for Research.

    Science.gov (United States)

    Carter-Harris, Lisa; Bartlett Ellis, Rebecca; Warrick, Adam; Rawl, Susan

    2016-06-15

    for wider reach at a lower cost while providing privacy and flexibility for potential study participants. The study's findings extend recent work of other researchers who have demonstrated Facebook's utility with younger smokers, and Facebook is an effective tool to recruit older smokers. Furthermore, Facebook is a cost-effective alternative to traditional newspaper advertisement offering a new, affordable venue to recruit large numbers of older smokers efficiently.

  13. Beyond Traditional Newspaper Advertisement: Leveraging Facebook-Targeted Advertisement to Recruit Long-Term Smokers for Research

    Science.gov (United States)

    Warrick, Adam

    2016-01-01

    recruitment into research studies that offer the potential for wider reach at a lower cost while providing privacy and flexibility for potential study participants. The study’s findings extend recent work of other researchers who have demonstrated Facebook’s utility with younger smokers, and Facebook is an effective tool to recruit older smokers. Furthermore, Facebook is a cost-effective alternative to traditional newspaper advertisement offering a new, affordable venue to recruit large numbers of older smokers efficiently. PMID:27306780

  14. Assessment of reflectivity of noise barriers in the far field – QUIESST method compared to traditional approach

    NARCIS (Netherlands)

    Roo, F. de

    2013-01-01

    The sound reflectivity of noise barriers elements is one of the major acoustic product characteristics. Traditionally this property was tested in reverberation rooms according to EN 1793-1 and the results were used to predict the effect of sound reflections in the far field. As in many cases these

  15. Comparison of iPad applications with traditional activities using person-centred care approach: impact on well-being for persons with dementia.

    Science.gov (United States)

    Leng, Fong Yoke; Yeo, Donald; George, Stacey; Barr, Christopher

    2014-03-01

    Professionals working with people with dementia need to develop new activities that occupy patients and increase positive emotions. Dementia care mapping is a reliable method of measuring well-being during activities with people with dementia. The iPad has many applications that may be suitable as a group activity for persons with dementia. Six people with dementia took part in two traditional and two iPad activities over two days. Well-being was recorded using dementia care mapping. Subjects displayed similar or better levels of well-being during iPad activities than traditional activities. A larger variation of behaviors was seen during iPad activities than traditional activities. With detailed planning using a person-centred care approach, iPad group activity has the potential to be as effective and engaging as other conventional activities in achieving well-being.

  16. Novel approach to parental permission and child assent for research: improving comprehension.

    Science.gov (United States)

    O'Lonergan, Theresa A; Forster-Harwood, Jeri E

    2011-05-01

    The aim of this research was to test a multimedia permission/assent (P/A) process. The overall hypothesis was that children and their parents exposed to a multimedia P/A process would have better comprehension compared with those exposed to a text-based process. Traditional and multimedia P/A processes were created by using an innovative learning-objective approach. A total of 194 parent-child dyads (children aged 11-14 years) were enrolled: 24 dyads in a prestudy testing P/A components for preference and effect on comprehension and 170 dyads in a randomized trial of a multimedia or paper P/A process for a hypothetical study. Participants were predominantly white and were from a metropolitan area served by a tertiary care pediatric hospital and outpatient facility. Comprehension of 8 essential elements of the P/A process was assessed. The majority of prestudy subjects preferred the video version of the dual-energy radiograph absorptiometry description over the animated and paper versions combined (41 of 48 [85%]; P better overall comprehension compared with the paper P/A process (P = .0009), and there were highly significant differences in understanding of study procedures (P = .0002) and risks (P multimedia group had significantly better overall comprehension (P = .03). Multimedia approaches to the research P/A process may improve overall understanding of research participation for children and parents. Improved understanding of study-specific research components (rather than research rights) may improve overall comprehension.

  17. Researching intimacy through social media: A cross-platform approach

    Directory of Open Access Journals (Sweden)

    Cristina Miguel

    2016-06-01

    Full Text Available This paper aims to contribute to the understanding of how to study the way people build intimacy and manage privacy through social media interaction. It explores the research design and methodology of a research project based on a multi-sited case study composed of three different social media platforms: Badoo, CouchSurfing, and Facebook. This cross-platform approach is useful to observe how intimacy is often negotiated across different platforms. The research project focuses on the cities of Leeds (UK and Barcelona (Spain. In particular, this article discusses the methods used to recruit participants and collect data for that study - namely, participant observation, semi-structured interviews, and user profiles analysis. This cross-platform approach and multi-method research design is helpful to investigate the nature of intimacy practices facilitated by social media at several levels: online/offline, across different platforms, among different types of relationships, within both new and existing relationships, and in different locations

  18. Research regarding agro-tourism stage in Apuseni Mountains area and capitalize of traditional products through this

    Directory of Open Access Journals (Sweden)

    Ramona Ciolac

    2013-05-01

    Full Text Available Most studies have shown that rural tourism combined with rural resources and traditional products would be an important "tool" for revitalizing the rural economy, and that they should be essential components of the rural economy development strategy, desirable goal for Apuseni Mountains. A great part of the localities from this area are great keeper of traditions. If on the customs and traditions we put the mountain natural resources and specific traditional products results a valuable tourist product that could local increase revenue and attract young people in rural areas. Many rural areas have a potentially remarkable natural and cultural history, and those who developed the required tourist infrastructure (boarding/private farms, and realized tourist opportunity and have used it with success.

  19. A licence renewal approach for the NRU research reactor

    International Nuclear Information System (INIS)

    Natalizio, A.; Gumley, P.

    1991-01-01

    Licence Renewal is not only a subject that is being addressed for power reactors, but it is one of immediate interest for a number of research facilities, world-wide. In Canada, research reactors and power reactors are issued an operating licence for a limited term (typically two years), hence, licence renewal is done on a regular basis. Therefore, licence renewal in the Canadian context is different than in the context of this topical meeting. The NRU research reactor facility is being assessed for a licence renewal beyond its original design life. This paper describes the licence renewal approach, the assessments being performed to establish the condition of the facility, and the Safety Assessment Basis which defines the requirements for licence renewal. The current status of the assessments is also described. (author)

  20. Origins of management accounting according to different research approaches

    Directory of Open Access Journals (Sweden)

    Anna Szychta

    2016-07-01

    Full Text Available The aim of the article is to specify the causes, places and periods of origin of the application of manage-ment accounting in accordance with the views of the foreign supporters of the four main approaches to research on the development of management accounting. The article highlights the various possibilities of interpretation by historians of past events and processes in the practice of management accounting dependingon the types of sources included in research and conceptual basis for discussion and interpretation of the past. The author uses the review, analysis and synthesis of thoughts and opinions of the authors of select-ed publications from the extensive English-language literature of the subject. This article constitutes an input to the discussion about the need to extend the research in Poland in the area of accounting history, including management accounting history.

  1. Respiratory sensitization and allergy: Current research approaches and needs

    International Nuclear Information System (INIS)

    Boverhof, Darrell R.; Billington, Richard; Gollapudi, B. Bhaskar; Hotchkiss, John A.; Krieger, Shannon M.; Poole, Alan; Wiescinski, Connie M.; Woolhiser, Michael R.

    2008-01-01

    There are currently no accepted regulatory models for assessing the potential of a substance to cause respiratory sensitization and allergy. In contrast, a number of models exist for the assessment of contact sensitization and allergic contact dermatitis (ACD). Research indicates that respiratory sensitizers may be identified through contact sensitization assays such as the local lymph node assay, although only a small subset of the compounds that yield positive results in these assays are actually respiratory sensitizers. Due to the increasing health concerns associated with occupational asthma and the impending directives on the regulation of respiratory sensitizers and allergens, an approach which can identify these compounds and distinguish them from contact sensitizers is required. This report discusses some of the important contrasts between respiratory allergy and ACD, and highlights several prominent in vivo, in vitro and in silico approaches that are being applied or could be further developed to identify compounds capable of causing respiratory allergy. Although a number of animal models have been used for researching respiratory sensitization and allergy, protocols and endpoints for these approaches are often inconsistent, costly and difficult to reproduce, thereby limiting meaningful comparisons of data between laboratories and development of a consensus approach. A number of emerging in vitro and in silico models show promise for use in the characterization of contact sensitization potential and should be further explored for their ability to identify and differentiate contact and respiratory sensitizers. Ultimately, the development of a consistent, accurate and cost-effective model will likely incorporate a number of these approaches and will require effective communication, collaboration and consensus among all stakeholders

  2. Strategic approaches to CBRN decontamination research design and investment

    International Nuclear Information System (INIS)

    Jutro, P.

    2009-01-01

    Research funding is society's investment in its future, but in difficult economic times, investment in anything with a less than immediate payoff can be a challenge. Making federal research investment decisions for large scale issues with political, social, and economic consequences has always involved competition for available resources played out in universities, Federal executive departments and agencies, and in the authorizing and appropriating committees and subcommittees of the legislature. Designing a research program that relates to the national need for a long-term strategic approach to consequence management is a challenge in the natural and social sciences as well as in political analysis. A successful effort must involve intensive interactions by research managers with consequence managers, evaluation of the relative cost and potential effectiveness of alternative research strategies, an estimation of time to completion and potential for success of research, and having a common understanding of roles and responsibilities of national and local governments, as well as private enterprise and affected individuals. All this must be undertaken in concert with the development of risk communication strategies that are science-based but deal with managing societal expectations based on the costs and practicality of potential alternative suites of solutions.(author)

  3. Health-related quality of life research and the capability approach of Amartya Sen.

    Science.gov (United States)

    Verkerk, M A; Busschbach, J J; Karssing, E D

    2001-01-01

    Standardised health-related quality of life questionnaires play an increasing role as measures of outcome in the evaluation of health care interventions. However, problems can arise when the selected functions or dimensions of such standardised measures are not in line with the intervention that is the focus of the research. Furthermore, the subjective element of quality of life makes standardised questionnaires vulnerable to the coping mechanism, thereby decreasing their sensitivity. The capability approach of the economist and philosopher Amartya Sen offers a descriptive concept that contributes to a better understanding of these problems. This article provides an introduction to the ideas of Sen for researchers who wish to go beyond the traditional framework of measuring health-related quality of life.

  4. Re-description and Reassignment of the Damselfish Abudefduf luridus (Cuvier, 1830) Using Both Traditional and Geometric Morphometric Approaches

    Energy Technology Data Exchange (ETDEWEB)

    Cooper, W. James [Washington State Univ., Pullman, WA (United States); Albertson, R Craig [Univ. of Massachusetts, Amherst, MA (United States); Jacob, Rick E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Westneat, Mark W. [Field Museum of Natural History, Chicago, IL (United States)

    2014-12-01

    Here we present a re-description of Abudefduf luridus and reassign it to the genus Similiparma. We supplement traditional diagnoses and descriptions of this species with quantitative anatomical data collected from a family-wide geometric morphometric analysis of head morphology (44 species representing all 30 damselfish genera) and data from cranial micro-CT scans of fishes in the genus Similiparma. The use of geometric morphometric analyses (and other methods of shape analysis) permits detailed comparisons between the morphology of specific taxa and the anatomical diversity that has arisen in an entire lineage. This provides a particularly useful supplement to traditional description methods and we recommend the use of such techniques by systematists. Similiparma and its close relatives constitute a branch of the damselfish phylogenetic tree that predominantly inhabits rocky reefs in the Atlantic and Eastern Pacific, as opposed to the more commonly studied damselfishes that constitute a large portion of the ichthyofauna on all coral-reef communities.

  5. Marine Resource Management in the Hawaiian Archipelago: The Traditional Hawaiian System in Relation to the Western Approach

    Directory of Open Access Journals (Sweden)

    P. L. Jokiel

    2011-01-01

    Full Text Available Over a period of many centuries the Polynesians who inhabited Hawai‘i developed a carefully regulated and sustainable “ahupua‘a” management system that integrated watershed, freshwater and nearshore marine resources based on the fundamental linkages between all ecosystems from the mountain tops to the sea. This traditional scheme employed adaptive management practices keyed to subtle changes in natural resources. Sophisticated social controls on resource utilization were an important component of the system. Over the past two centuries a “Western system” gradually replaced much of the traditional Hawaiian system. There are major differences between the two systems in the areas of management practices, management focus, knowledge base, dissemination of information, resource monitoring, legal authority, access rights, stewardship and enforcement. However, there is a recent shift toward incorporating elements of the traditional scheme using methods and terminology acceptable and appropriate to present day realities. This trend is exemplified by the management plan for the newly formed Papahānaumokuākea Marine National Monument in the Northwestern Hawaiian Islands. This is one of the largest protected areas in the world and is being managed with a focus on Native Hawaiian cultural values in relation to conservation, ecological, historical, scientific, and educational resource protection.

  6. Spatial extent in demographic research - approach and problems

    Directory of Open Access Journals (Sweden)

    Knežević Aleksandar

    2015-01-01

    Full Text Available One of the starting methodological problems in demographic research is the definition of spatial extent, which mostly doesn’t correspond to spatial extent already defined by different levels of administrative-territorial unitsthat are used for distribution of usable statistical data. That’s why determining the spatial extent of a demographic research is closely tied with administrative-territorial division of the territory that is being researched, wherein the fact that differentiation of demographic phenomena and processes cannot be the only basis of setting the principles of regionalization must be strictly acknowledged. This problem is particularly common in historical demographic analyses of geographically determined wholes, which are in administratively-territorial sense represented by one or more smaller territorial units, with their borders changing through the history, which directly affects comparability of the statistical data, and makes it considerably more difficult to track demographic change through longer time intervals. The result of these efforts is usually a solution based on a compromise which enables us to examine the dynamics of population change with little deviation from already defined borders of regional geographic wholes. For that reason in this paper the problem of defining spatial extent in demographic research is examined trough several different approaches in case of Eastern Serbia, as a geographically determined region, a historic area, a spatially functioning whole and as a statistical unit for demographic research, with no judgment calls in regard to any of the regionalization principles. [Projekat Ministarstva nauke Republike Srbije, br. III 47006

  7. An integrative approach to research of deforestation under concession management

    International Nuclear Information System (INIS)

    Hepner, G.F.; Walker, R.T.

    1991-01-01

    A methodological approach integrating questionnaire research of tropical foresters with analyses of the actual patterns of concession logging and land use activities portrayed on various types of satellite imagery is discussed. The imagery analysis is necessary to: document the location place and magnitude of forest utilization and change in concession areas; confirm that responses vis-a-vis deforestation in the questionnaire correspond to observable behaviors as evidenced by the actual patterns of logging activities; and document the postharvest land utilization and conversion to other land uses. It is argued that this approach will link the process and pattern of logging activities to reveal the main factors leading to deforestation under the concession system of management. 20 refs

  8. Pedagogy before Technology: A Design-Based Research Approach to Enhancing Skills Development in Paramedic Science Using Mixed Reality

    OpenAIRE

    Michael Cowling; James Birt

    2018-01-01

    In health sciences education, there is growing evidence that simulation improves learners’ safety, competence, and skills, especially when compared to traditional didactic methods or no simulation training. However, this approach to simulation becomes difficult when students are studying at a distance, leading to the need to develop simulations that suit this pedagogical problem and the logistics of this intervention method. This paper describes the use of a design-based research (DBR) method...

  9. Multi-Contextual Segregation and Environmental Justice Research: Toward Fine-Scale Spatiotemporal Approaches

    Directory of Open Access Journals (Sweden)

    Yoo Min Park

    2017-10-01

    Full Text Available Many environmental justice studies have sought to examine the effect of residential segregation on unequal exposure to environmental factors among different social groups, but little is known about how segregation in non-residential contexts affects such disparity. Based on a review of the relevant literature, this paper discusses the limitations of traditional residence-based approaches in examining the association between socioeconomic or racial/ethnic segregation and unequal environmental exposure in environmental justice research. It emphasizes that future research needs to go beyond residential segregation by considering the full spectrum of segregation experienced by people in various geographic and temporal contexts of everyday life. Along with this comprehensive understanding of segregation, the paper also highlights the importance of assessing environmental exposure at a high spatiotemporal resolution in environmental justice research. The successful integration of a comprehensive concept of segregation, high-resolution data and fine-grained spatiotemporal approaches to assessing segregation and environmental exposure would provide more nuanced and robust findings on the associations between segregation and disparities in environmental exposure and their health impacts. Moreover, it would also contribute to significantly expanding the scope of environmental justice research.

  10. Multi-Contextual Segregation and Environmental Justice Research: Toward Fine-Scale Spatiotemporal Approaches.

    Science.gov (United States)

    Park, Yoo Min; Kwan, Mei-Po

    2017-10-10

    Many environmental justice studies have sought to examine the effect of residential segregation on unequal exposure to environmental factors among different social groups, but little is known about how segregation in non-residential contexts affects such disparity. Based on a review of the relevant literature, this paper discusses the limitations of traditional residence-based approaches in examining the association between socioeconomic or racial/ethnic segregation and unequal environmental exposure in environmental justice research. It emphasizes that future research needs to go beyond residential segregation by considering the full spectrum of segregation experienced by people in various geographic and temporal contexts of everyday life. Along with this comprehensive understanding of segregation, the paper also highlights the importance of assessing environmental exposure at a high spatiotemporal resolution in environmental justice research. The successful integration of a comprehensive concept of segregation, high-resolution data and fine-grained spatiotemporal approaches to assessing segregation and environmental exposure would provide more nuanced and robust findings on the associations between segregation and disparities in environmental exposure and their health impacts. Moreover, it would also contribute to significantly expanding the scope of environmental justice research.

  11. A network approach for researching partnerships in health.

    Science.gov (United States)

    Lewis, Jenny M

    2005-10-07

    The last decade has witnessed a significant move towards new modes of governing that are based on coordination and collaboration. In particular, local level partnerships have been widely introduced around the world. There are few comprehensive approaches for researching the effects of these partnerships. The aim of this paper is to outline a network approach that combines structure and agency based explanations to research partnerships in health. Network research based on two Primary Care Partnerships (PCPs) in Victoria is used to demonstrate the utility of this approach. The paper examines multiple types of ties between people (structure), and the use and value of relationships to partners (agency), using interviews with the people involved in two PCPs--one in metropolitan Melbourne and one in a rural area. Network maps of ties based on work, strategic information and policy advice, show that there are many strong connections in both PCPs. Not surprisingly, PCP staff are central and highly connected. Of more interest are the ties that are dependent on these dedicated partnership staff, as they reveal which actors become weakly linked or disconnected without them. Network measures indicate that work ties are the most dispersed and strategic information ties are the most concentrated around fewer people. Divisions of general practice are weakly linked, while local government officials and Department of Human Services (DHS) regional staff appear to play important bridging roles. Finally, the relationships between partners have changed and improved, and most of those interviewed value their new or improved links with partners. Improving service coordination and health promotion planning requires engaging people and building strong relationships. Mapping ties is a useful means for assessing the strengths and weaknesses of partnerships, and network analysis indicates concentration and dispersion, the importance of particular individuals, and the points at which they

  12. The personnel economics approach to public workforce research.

    Science.gov (United States)

    Gibbs, Michael

    2009-11-01

    This article argues that the relatively new field of personnel economics (PE) holds strong potential as a tool for studying public sector workforces. This subfield of labor economics is based on a strong foundation of microeconomics, which provides a robust theoretical foundation for studying workforce and organizational design issues. PE has evolved on this foundation to a strong practical emphasis, with theoretical insights designed for practical use and with strong focus on empirical research. The field is also characterized by creative data entrepreneurship. The types of datasets that personnel economists use are described. If similar datasets can be obtained for public sector workforces, PE should be a very useful approach for studying them.

  13. Archive of oral tradition of the Centre for Asia Minor Studies: its formation and its contribution to research

    Directory of Open Access Journals (Sweden)

    Evi Kapoli

    2008-08-01

    Full Text Available L’archive d’histoire orale du Centre d’Études d’Asie Mineure. Création et rôle dans l’encadrement de la recherche. En 1930, quelques années après l’échange de populations entre la Turquie et la Grèce, Melpo Logotheti-Merlier (1890-1979 créé le Centre d’études d’Asie Mineure dans le but d’assurer la sauvegarde de l’histoire et de la culture des populations grecques réfugiées d’Asie Mineure. Le projet consista à demander aux réfugiés de décrire les lieux où ils avaient vécu, et de donner le maximum d’informations sur leur mode de vie, leurs pratiques religieuses ainsi que sur les relations qu’ils entretenaient avec leurs voisins turcs. Enfin, des questions leur étaient également posées sur leur installation en Grèce. Les archives réunies au Centre d’études d’Asie Mineure comprennent les témoignages oraux de 5 000 réfugiés soit environ 300 000 pages manuscrites reprenant les interviews menés depuis le début des années 1930 jusqu’aux années 1970. Ces archives de la tradition orale sont porteuses d’une triple empreintes, celle de Melpo Merlier, elle-même, celles des chercheurs qui ont travaillé au centre mais également celle des informateurs, les réfugiés eux-mêmes. Cet article se propose d’examiner comment ces archives témoignent de la manière dont les réfugiés – et, avec eux, une partie de la société grecque - ont vécu ce bouleversement qui a complètement transformé leur vie et comment ils ont réussi à sauvegarder la mémoire de leur passé.The archives of oral history of the Centre for Asia Minor Studies: its formation and its contribution to research. In 1930, just a few years after the population exchange was agreed upon in Lausanne, Melpo Logotheti-Merlier (1890-1979 established the Center for Asia Minor Studies with the aim of “salvaging” the history and culture of Asia Minor Hellenism. Refugees were called to describe the physical environment, social

  14. The Pluralistic Water Research Concept: A New Human-Water System Research Approach

    Directory of Open Access Journals (Sweden)

    Mariele Evers

    2017-11-01

    Full Text Available The use and management of water systems is influenced by a number of factors, such as economic growth, global change (e.g., urbanization, hydrological-climatic changes, politics, history and culture. Despite noteworthy efforts to develop integrative approaches to analyze water-related problems, human-water research remains a major challenge for scholars and decision makers due to the increasing complexity of human and water systems interactions. Although existing concepts try to integrate the social and water dimensions, they usually have a disciplinary starting point and perspective, which can represent an obstacle to true integration in human-water research. Hence, a pluralistic approach is required to better understand the interactions between human and water systems. This paper discusses prominent human-water concepts (Integrated Water Resources Management (IWRM, socio-hydrology, and political ecology/hydrosocial approach and presents a newly developed concept termed pluralistic water research (PWR. This is not only a pluralistic but also an integrative and interdisciplinary approach which aims to coherently and comprehensively integrate human-water dimensions. The different concepts are illustrated in a synopsis, and diverse framing of research questions are exemplified. The PWR concept integrates physical and social sciences, which enables a comprehensive analysis of human-water interactions and relations. This can lead to a better understanding of water-related issues and potentially sustainable trajectories.

  15. A MOOC approach for training researchers in developing countries

    Directory of Open Access Journals (Sweden)

    Ravi Murugesan

    2017-03-01

    Full Text Available We report on an online course in research writing offered in a massive open online course (MOOC format for developing country researchers. The concepts of cognitive presence, teacher presence, and social presence informed the design of the course, with a philosophy of strong social interaction supported by guest facilitators. The course was developed with low-bandwidth elements and hosted on a Moodle site. It was offered twice as a MOOC and 2830 learners from more than 90 countries, mainly in the developing world, took part. The average completion rate was 53%. Female learners and learners who were active in the forums were more likely to complete the course. Our MOOC approach may be a useful model for continuing professional development training in the developing world.

  16. An Institutional Approach to Developing Research Data Management Infrastructure

    Directory of Open Access Journals (Sweden)

    James A. J. Wilson

    2011-10-01

    Full Text Available This article outlines the work that the University of Oxford is undertaking to implement a coordinated data management infrastructure. The rationale for the approach being taken by Oxford is presented, with particular attention paid to the role of each service division. This is followed by a consideration of the relative advantages and disadvantages of institutional data repositories, as opposed to national or international data centres. The article then focuses on two ongoing JISC-funded projects, ‘Embedding Institutional Data Curation Services in Research’ (Eidcsr and ‘Supporting Data Management Infrastructure for the Humanities’ (Sudamih. Both projects are intra-institutional collaborations and involve working with researchers to develop particular aspects of infrastructure, including: University policy, systems for the preservation and documentation of research data, training and support, software tools for the visualisation of large images, and creating and sharing databases via the Web (Database as a Service.

  17. A blended learning approach to teaching sociolinguistic research methods

    Directory of Open Access Journals (Sweden)

    Olivier, Jako

    2014-12-01

    Full Text Available This article reports on the use of Wiktionary, an open source online dictionary, as well as generic wiki pages within a university’s e-learning environment as teaching and learning resources in an Afrikaans sociolinguistics module. In a communal constructivist manner students learnt, but also constructed learning content. From the qualitative research conducted with students it is clear that wikis provide for effective facilitation of a blended learning approach to sociolinguistic research. The use of this medium was positively received, however, some students did prefer handing in assignments in hard copy. The issues of computer literacy and access to the internet were also raised by the respondents. The use of wikis and Wiktionary prompted useful unplanned discussions around reliability and quality of public wikis. The use of a public wiki such as Wiktionary served as encouragement for students as they were able to contribute to the promotion of Afrikaans in this way.

  18. Combining genomic and proteomic approaches for epigenetics research

    Science.gov (United States)

    Han, Yumiao; Garcia, Benjamin A

    2014-01-01

    Epigenetics is the study of changes in gene expression or cellular phenotype that do not change the DNA sequence. In this review, current methods, both genomic and proteomic, associated with epigenetics research are discussed. Among them, chromatin immunoprecipitation (ChIP) followed by sequencing and other ChIP-based techniques are powerful techniques for genome-wide profiling of DNA-binding proteins, histone post-translational modifications or nucleosome positions. However, mass spectrometry-based proteomics is increasingly being used in functional biological studies and has proved to be an indispensable tool to characterize histone modifications, as well as DNA–protein and protein–protein interactions. With the development of genomic and proteomic approaches, combination of ChIP and mass spectrometry has the potential to expand our knowledge of epigenetics research to a higher level. PMID:23895656

  19. Comparing Multiple Intelligences Approach with Traditional Teaching on Eight Grade Students' Achievement in and Attitudes toward Science

    Science.gov (United States)

    Kaya, Osman Nafiz; Dogan, Alev; Gokcek, Nur; Kilic, Ziya; Kilic, Esma

    2007-01-01

    The purpose of this study was to investigate the effects of multiple intelligences (MI) teaching approach on 8th Grade students' achievement in and attitudes toward science. This study used a pretest-posttest control group experimental design. While the experimental group (n=30) was taught a unit on acids and bases using MI teaching approach, the…

  20. Unveiling Cebuano Traditional Healing Practices

    Directory of Open Access Journals (Sweden)

    ZachiaRaiza Joy S. Berdon

    2016-02-01

    Full Text Available This study aims to identify the features of Cebuano’s traditional healing practices. Specifically, it also answers the following objectives: analyze traditional healing in Cebuano’s perspectives, explain the traditional healing process practiced in terms of the traditional healers’ belief, and extrapolate perceptions of medical practitioners toward traditional healing. This study made use of qualitative approach, among five traditional healers who performed healing for not less than ten years, in the mountain barangays of Cebu City. These healers served as the primary informants who were selected because of their popularity in healing. The use of open-ended interview in local dialect and naturalistic observation provided a free listing of their verbatim accounts were noted and as primary narratives. Participation in the study was voluntary and participants were interviewed privately after obtaining their consent. The Cebuano traditional healing practices or “panambal” comprise the use of “himolso” (pulse-checking, “palakaw” (petition, “pasubay” (determining what causes the sickness and its possible means of healing, “pangalap” (searching of medicinal plants for “palina” (fumigation, “tayhop” (gentle-blowing, “tutho” (saliva-blowing,“tuob” (boiling, “orasyon” (mystical prayers, “hilot” (massage, and “barang” (sorcery. Though traditional with medical science disapproval, it contributes to a mystical identity of Cebuano healers, as a manifestation of folk Catholicism belief, in order to do a good legacy to the community that needs help. For further study, researchers may conduct further the studies on the: curative effects of medicinal plants in Cebu, psychological effect pulsechecking healed persons by the mananambal, and unmasking the other features of traditional healing.

  1. [Investigation methodology and application on scientific and technological personnel of traditional Chinese medical resources based on data from Chinese scientific research paper].

    Science.gov (United States)

    Li, Hai-yan; Li, Yuan-hai; Yang, Yang; Liu, Fang-zhou; Wang, Jing; Tian, Ye; Yang, Ce; Liu, Yang; Li, Meng; Sun Li-ying

    2015-12-01

    The aim of this study is to identify the present status of the scientific and technological personnel in the field of traditional Chinese medicine (TCM) resource science. Based on the data from Chinese scientific research paper, an investigation regarding the number of the personnel, the distribution, their output of paper, their scientific research teams, high-yield authors and high-cited authors was conducted. The study covers seven subfields of traditional Chinese medicine identification, quality standard, Chinese medicine cultivation, harvest processing of TCM, market development and resource protection and resource management, as well as 82 widely used Chinese medicine species, such as Ginseng and Radix Astragali. One hundred and fifteen domain authority experts were selected based on the data of high-yield authors and high-cited authors. The database system platform "Skilled Scientific and Technological Personnel in the field of Traditional Chinese Medicine Resource Science-Chinese papers" was established. This platform successfully provided the retrieval result of the personnel, output of paper, and their core research team by input the study field, year, and Chinese medicine species. The investigation provides basic data of scientific and technological personnel in the field of traditional Chinese medicine resource science for administrative agencies and also evidence for the selection of scientific and technological personnel and construction of scientific research teams.

  2. Student performance and their perception of a patient-oriented problem-solving approach with audiovisual aids in teaching pathology: a comparison with traditional lectures

    Directory of Open Access Journals (Sweden)

    Arjun Singh

    2010-12-01

    Full Text Available Arjun SinghDepartment of Pathology, Sri Venkateshwara Medical College Hospital and Research Centre, Pondicherry, IndiaPurpose: We use different methods to train our undergraduates. The patient-oriented problem-solving (POPS system is an innovative teaching–learning method that imparts knowledge, enhances intrinsic motivation, promotes self learning, encourages clinical reasoning, and develops long-lasting memory. The aim of this study was to develop POPS in teaching pathology, assess its effectiveness, and assess students’ preference for POPS over didactic lectures.Method: One hundred fifty second-year MBBS students were divided into two groups: A and B. Group A was taught by POPS while group B was taught by traditional lectures. Pre- and post-test numerical scores of both groups were evaluated and compared. Students then completed a self-structured feedback questionnaire for analysis.Results: The mean (SD difference in pre- and post-test scores of groups A and B was 15.98 (3.18 and 7.79 (2.52, respectively. The significance of the difference between scores of group A and group B teaching methods was 16.62 (P < 0.0001, as determined by the z-test. Improvement in post-test performance of group A was significantly greater than of group B, demonstrating the effectiveness of POPS. Students responded that POPS facilitates self-learning, helps in understanding topics, creates interest, and is a scientific approach to teaching. Feedback response on POPS was strong in 57.52% of students, moderate in 35.67%, and negative in only 6.81%, showing that 93.19% students favored POPS over simple lectures.Conclusion: It is not feasible to enforce the PBL method of teaching throughout the entire curriculum; However, POPS can be incorporated along with audiovisual aids to break the monotony of dialectic lectures and as alternative to PBL.Keywords: medical education, problem-solving exercise, problem-based learning

  3. [Construction of research system for processing mechanism of traditional Chinese medicine based on chemical composition transformation combined with intestinal absorption barrier].

    Science.gov (United States)

    Sun, E; Xu, Feng-Juan; Zhang, Zhen-Hai; Wei, Ying-Jie; Tan, Xiao-Bin; Cheng, Xu-Dong; Jia, Xiao-Bin

    2014-02-01

    Based on practice of Epimedium processing mechanism for many years and integrated multidisciplinary theory and technology, this paper initially constructs the research system for processing mechanism of traditional Chinese medicine based on chemical composition transformation combined with intestinal absorption barrier, which to form an innovative research mode of the " chemical composition changes-biological transformation-metabolism in vitro and in vivo-intestinal absorption-pharmacokinetic combined pharmacodynamic-pharmacodynamic mechanism". Combined with specific examples of Epimedium and other Chinese herbal medicine processing mechanism, this paper also discusses the academic thoughts, research methods and key technologies of this research system, which will be conducive to systematically reveal the modem scientific connotation of traditional Chinese medicine processing, and enrich the theory of Chinese herbal medicine processing.

  4. An evidence-based approach to medicinal plants for the treatment of sperm abnormalities in traditional Persian medicine.

    Science.gov (United States)

    Tahvilzadeh, M; Hajimahmoodi, M; Toliyat, T; Karimi, M; Rahimi, R

    2016-10-01

    Infertility is defined as inability of a sexually active couple to conceive after 1 year of regular intercourse without contraception. Male factors account for 20%-50% of cases of infertility. The aim of this study was to review medicinal plants that proposed to improve sperm abnormalities in traditional Persian medicine. For this purpose, PubMed, Scopus, GoogleScholar and Cochrane library were explored for medicinal plants used in traditional Persian medicine for sperm abnormalities to obtain studies giving any evidence for their efficacy and pharmacological mechanisms related to male infertility. Data were collected for the years 1966 to March 2015. For some of them, including Chlorophytum borivilianum, Crocus sativus, Nigella sativa, Sesamum indicum, Tribulus terrestris, Mucuna pruriens and Withania somnifera, more reliable evidence was found. The mechanisms involved in the beneficial effects of medicinal plants in sperm abnormalities are antioxidant, anti-inflammatory, anti-oedematous and venotonic activity as well as containing precursors for sperm production and increasing blood testosterone level. Various phytochemical categories including saponins, phytosterols, carotenoids, oxygenated volatile compounds, phenolic compounds and alkaloids seem to be responsible for these beneficial effects. Further studies are recommended for obtaining more conclusive results about the efficacy and safety of the mentioned medicinal plants. © 2016 Blackwell Verlag GmbH.

  5. Base technology approaches in materials research for future nuclear applications

    International Nuclear Information System (INIS)

    Kondo, Tatsuo

    1992-01-01

    In the development of advanced nuclear systems for future, majority of critical issues in material research and development are more or less related with the effects of neutron irradiation. The approaches to those issues in the past have been mainly concerned with interpretation of the facts and minor modification of existing materials, having been inevitably of passive nature. In combating against predicted complex effects arising from variety of critical parameters, approaches must be reviewed more strategically. Some attempts of shifting research programs to such a direction have been made at JAERI in the Base (Common) Technology Programs either by adding to or restructuring the existing tasks. Major tasks currently in progress after the reorientation are categorized in several disciplines including new tasks for material innovation and concept development for neutron sources. The efforts have been set forth since 1988, and a few of them are now mature to transfer to the tasks in the projects of advanced reactors. The paper reviews the status of some typical activities emphasizing the effects of the reorientation and possible extensions of the outcomes to future applications. (author)

  6. A systems medicine research approach for studying alcohol addiction.

    Science.gov (United States)

    Spanagel, Rainer; Durstewitz, Daniel; Hansson, Anita; Heinz, Andreas; Kiefer, Falk; Köhr, Georg; Matthäus, Franziska; Nöthen, Markus M; Noori, Hamid R; Obermayer, Klaus; Rietschel, Marcella; Schloss, Patrick; Scholz, Henrike; Schumann, Gunter; Smolka, Michael; Sommer, Wolfgang; Vengeliene, Valentina; Walter, Henrik; Wurst, Wolfgang; Zimmermann, Uli S; Stringer, Sven; Smits, Yannick; Derks, Eske M

    2013-11-01

    According to the World Health Organization, about 2 billion people drink alcohol. Excessive alcohol consumption can result in alcohol addiction, which is one of the most prevalent neuropsychiatric diseases afflicting our society today. Prevention and intervention of alcohol binging in adolescents and treatment of alcoholism are major unmet challenges affecting our health-care system and society alike. Our newly formed German SysMedAlcoholism consortium is using a new systems medicine approach and intends (1) to define individual neurobehavioral risk profiles in adolescents that are predictive of alcohol use disorders later in life and (2) to identify new pharmacological targets and molecules for the treatment of alcoholism. To achieve these goals, we will use omics-information from epigenomics, genetics transcriptomics, neurodynamics, global neurochemical connectomes and neuroimaging (IMAGEN; Schumann et al. ) to feed mathematical prediction modules provided by two Bernstein Centers for Computational Neurosciences (Berlin and Heidelberg/Mannheim), the results of which will subsequently be functionally validated in independent clinical samples and appropriate animal models. This approach will lead to new early intervention strategies and identify innovative molecules for relapse prevention that will be tested in experimental human studies. This research program will ultimately help in consolidating addiction research clusters in Germany that can effectively conduct large clinical trials, implement early intervention strategies and impact political and healthcare decision makers. © 2013 Society for the Study of Addiction.

  7. The Effectiveness Of Social Media (Facebook) Compared With More Traditional Advertising Methods for Recruiting Eligible Participants To Health Research Studies: A Randomized, Controlled Clinical Trial

    OpenAIRE

    Frandsen, Mai; Thow, Megan; Ferguson, Stuart G

    2016-01-01

    Background Recruiting participants for research studies can be difficult and costly. The popularity of social media platforms (eg, Facebook) has seen corresponding growth in the number of researchers turning to social networking sites and their embedded advertising frameworks to locate eligible participants for studies. Compared with traditional recruitment strategies such as print media, social media advertising has been shown to be favorable in terms of its reach (especially with hard-to-re...

  8. Research on the Influencing Mechanism of Traditional Cultural Values on Citizens’ Behavior Regarding the Reuse of Recycled Water

    Directory of Open Access Journals (Sweden)

    Kun Liu

    2018-01-01

    Full Text Available In order to explore the influence mechanism of traditional Chinese culture values on urban residents’ acceptance of the reuse of recycled water, this paper selects interdependent self-constructional indicators representing the dependency relation between people as the representative of traditional culture values. In this paper, interdependent self-constructional indicators are introduced based on a technology acceptance model (TAM, in order to establish a hypothesis model. Following this, the writer conducts a study that shows the influence on the acceptance of recycled water through the formation of interdependent self-construction. Finally, the influence mechanism of traditional cultural values on citizens’ behavior regarding the reuse of recycled water is determined. To start with, the writer verifies the reliability and validity of data from 584 samples, and then tests the goodness-of-fit between the sample data and the hypothesis model by AMOS21.0 (software. On this basis, the writer analyzes the direct and indirect influence through the hypothesis model and finds that the interdependent self-constructional intensity will accelerate the acceptance process of recycled water technology by positively influencing a change in the residents’ attitudes to recycled water. The conclusion shows that traditional Chinese cultural values have a certain influence on urban residents’ acceptance of the reuse of recycled water. Meanwhile, the writer clarifies the influence’s mechanism.

  9. Personalized translational epilepsy research - Novel approaches and future perspectives: Part II: Experimental and translational approaches.

    Science.gov (United States)

    Bauer, Sebastian; van Alphen, Natascha; Becker, Albert; Chiocchetti, Andreas; Deichmann, Ralf; Deller, Thomas; Freiman, Thomas; Freitag, Christine M; Gehrig, Johannes; Hermsen, Anke M; Jedlicka, Peter; Kell, Christian; Klein, Karl Martin; Knake, Susanne; Kullmann, Dimitri M; Liebner, Stefan; Norwood, Braxton A; Omigie, Diana; Plate, Karlheinz; Reif, Andreas; Reif, Philipp S; Reiss, Yvonne; Roeper, Jochen; Ronellenfitsch, Michael W; Schorge, Stephanie; Schratt, Gerhard; Schwarzacher, Stephan W; Steinbach, Joachim P; Strzelczyk, Adam; Triesch, Jochen; Wagner, Marlies; Walker, Matthew C; von Wegner, Frederic; Rosenow, Felix

    2017-11-01

    Despite the availability of more than 15 new "antiepileptic drugs", the proportion of patients with pharmacoresistant epilepsy has remained constant at about 20-30%. Furthermore, no disease-modifying treatments shown to prevent the development of epilepsy following an initial precipitating brain injury or to reverse established epilepsy have been identified to date. This is likely in part due to the polyetiologic nature of epilepsy, which in turn requires personalized medicine approaches. Recent advances in imaging, pathology, genetics, and epigenetics have led to new pathophysiological concepts and the identification of monogenic causes of epilepsy. In the context of these advances, the First International Symposium on Personalized Translational Epilepsy Research (1st ISymPTER) was held in Frankfurt on September 8, 2016, to discuss novel approaches and future perspectives for personalized translational research. These included new developments and ideas in a range of experimental and clinical areas such as deep phenotyping, quantitative brain imaging, EEG/MEG-based analysis of network dysfunction, tissue-based translational studies, innate immunity mechanisms, microRNA as treatment targets, functional characterization of genetic variants in human cell models and rodent organotypic slice cultures, personalized treatment approaches for monogenic epilepsies, blood-brain barrier dysfunction, therapeutic focal tissue modification, computational modeling for target and biomarker identification, and cost analysis in (monogenic) disease and its treatment. This report on the meeting proceedings is aimed at stimulating much needed investments of time and resources in personalized translational epilepsy research. This Part II includes the experimental and translational approaches and a discussion of the future perspectives, while the diagnostic methods, EEG network analysis, biomarkers, and personalized treatment approaches were addressed in Part I [1]. Copyright © 2017

  10. Personalized translational epilepsy research - Novel approaches and future perspectives: Part I: Clinical and network analysis approaches.

    Science.gov (United States)

    Rosenow, Felix; van Alphen, Natascha; Becker, Albert; Chiocchetti, Andreas; Deichmann, Ralf; Deller, Thomas; Freiman, Thomas; Freitag, Christine M; Gehrig, Johannes; Hermsen, Anke M; Jedlicka, Peter; Kell, Christian; Klein, Karl Martin; Knake, Susanne; Kullmann, Dimitri M; Liebner, Stefan; Norwood, Braxton A; Omigie, Diana; Plate, Karlheinz; Reif, Andreas; Reif, Philipp S; Reiss, Yvonne; Roeper, Jochen; Ronellenfitsch, Michael W; Schorge, Stephanie; Schratt, Gerhard; Schwarzacher, Stephan W; Steinbach, Joachim P; Strzelczyk, Adam; Triesch, Jochen; Wagner, Marlies; Walker, Matthew C; von Wegner, Frederic; Bauer, Sebastian

    2017-11-01

    Despite the availability of more than 15 new "antiepileptic drugs", the proportion of patients with pharmacoresistant epilepsy has remained constant at about 20-30%. Furthermore, no disease-modifying treatments shown to prevent the development of epilepsy following an initial precipitating brain injury or to reverse established epilepsy have been identified to date. This is likely in part due to the polyetiologic nature of epilepsy, which in turn requires personalized medicine approaches. Recent advances in imaging, pathology, genetics and epigenetics have led to new pathophysiological concepts and the identification of monogenic causes of epilepsy. In the context of these advances, the First International Symposium on Personalized Translational Epilepsy Research (1st ISymPTER) was held in Frankfurt on September 8, 2016, to discuss novel approaches and future perspectives for personalized translational research. These included new developments and ideas in a range of experimental and clinical areas such as deep phenotyping, quantitative brain imaging, EEG/MEG-based analysis of network dysfunction, tissue-based translational studies, innate immunity mechanisms, microRNA as treatment targets, functional characterization of genetic variants in human cell models and rodent organotypic slice cultures, personalized treatment approaches for monogenic epilepsies, blood-brain barrier dysfunction, therapeutic focal tissue modification, computational modeling for target and biomarker identification, and cost analysis in (monogenic) disease and its treatment. This report on the meeting proceedings is aimed at stimulating much needed investments of time and resources in personalized translational epilepsy research. Part I includes the clinical phenotyping and diagnostic methods, EEG network-analysis, biomarkers, and personalized treatment approaches. In Part II, experimental and translational approaches will be discussed (Bauer et al., 2017) [1]. Copyright © 2017 Elsevier Inc

  11. A new approach in cross-domain collaborative research

    Science.gov (United States)

    Diviacco, Paolo; Fox, Peter; Busato, Alessandro

    2016-04-01

    Scientific research commonly faces the study of complex systems where multiple skills and competences are needed at the same time. Effective collaboration among researchers then becomes of paramount importance. Multidisciplinary studies imply the use of information and knowledge from domains that can be rather far from each other. Notwithstanding this, researchers, need to understand: what they handle, how to extract what they need and eventually produce something that can be used also by others. The management of information and knowledge in this perspective is not trivial. To develop methods and tools able to support such activities we need to analyze how collaborative research takes place. Besides the standard view that picture scientists committed to their endeavour to achieve solid and undebatable results, modern epistemology and sociology of science added a more fluid perspective where science can be considered mostly a social construct conditioned also by cognitive issues. These aspects cannot be obliterated; on the contrary they need to be carefully taken into consideration. Information is to be built from different perspectives and ways of thinking by actors with different point of views, approaches and aims, and in this, data should be understandable by all the designated community. In fact different communities develop their own ways of thinking, language and even myths, in other words they can be considered such as different cultures. To address these issues we invoke two strategies: (I) to formalize all the knowledge relevant for the study. This will means resolving all conflicting models among actors; something that is theoretically and has been demonstrated practically, very difficult to achieve. (II) Exploit the results of ethnographic studies conducted in the 1990's that explained how the introduction of representative artifacts allow different cultures to understand and use the same concepts in a different way. Both approaches have limitations and

  12. Understanding Patient Values and the Manifestations in Clinical Research with Traditional Chinese Medicine—With Practical Suggestions for Trial Design and Implementation

    Directory of Open Access Journals (Sweden)

    Wei Mu

    2013-01-01

    Full Text Available Objective. To define patient values, identify their manifestations in a randomized clinical trial, and investigate the possible implications for clinical research of traditional Chinese medicine. Methods. We categorized patient values manifestations into patient choice, preference, compliance, and patient-reported outcomes and summarized the underlying personal values through purposeful electronic searches for relevant reports. By hypothesizing a set of positive versus negative circumstances occurring in the enrollment, intervention allocation, treatment, and the follow-up stage of a trial, it is possible to discuss the potential implications of patient values manifestation on a trial with traditional Chinese medicine. Results. Patient values and its manifestations are ubiquitous in the process of clinical research with traditional Chinese medicine. These values may provide motivation for participation or engender the internal and external validity of the study. Conclusions. Trialists should attach sufficient importance to the needs and concerns of individual participant. To incorporate patient values into the design and conduct of a clinical study with traditional Chinese medicine, researchers are recommended to adopt participant-friendly design and use patient-reported outcomes, take convenience-for-patients measures, and help foster rational beliefs and behaviors of trial participants.

  13. Understanding patient values and the manifestations in clinical research with traditional chinese medicine-with practical suggestions for trial design and implementation.

    Science.gov (United States)

    Mu, Wei; Shang, Hongcai

    2013-01-01

    Objective. To define patient values, identify their manifestations in a randomized clinical trial, and investigate the possible implications for clinical research of traditional Chinese medicine. Methods. We categorized patient values manifestations into patient choice, preference, compliance, and patient-reported outcomes and summarized the underlying personal values through purposeful electronic searches for relevant reports. By hypothesizing a set of positive versus negative circumstances occurring in the enrollment, intervention allocation, treatment, and the follow-up stage of a trial, it is possible to discuss the potential implications of patient values manifestation on a trial with traditional Chinese medicine. Results. Patient values and its manifestations are ubiquitous in the process of clinical research with traditional Chinese medicine. These values may provide motivation for participation or engender the internal and external validity of the study. Conclusions. Trialists should attach sufficient importance to the needs and concerns of individual participant. To incorporate patient values into the design and conduct of a clinical study with traditional Chinese medicine, researchers are recommended to adopt participant-friendly design and use patient-reported outcomes, take convenience-for-patients measures, and help foster rational beliefs and behaviors of trial participants.

  14. The backbone of research in modern education in the context of the competence approach

    Directory of Open Access Journals (Sweden)

    Raitina Margarita

    2016-01-01

    Full Text Available Modern society, which sets problems of translating culture in a new way, determines new criteria for the educational paradigm. Globalization tendencies in modern educational environment induce the problem of necessity to integrate educational and scientific resources into Russian education. The aim of this article is to demonstrate a significant part of scientific research as a consistent factor in formation of the competence-based model of a professional. It is shown that students’ research work beyond the process of education becomes a unique sort of teaching activity, which has a number of essential differences from the main traditional teaching techniques for compulsory courses. The results of students’ research work in the ecological situation of Siberian region are presented. The competencies acquired by students during this work are revealed. It is noticed that integrating the theme of students’ research work with compulsory courses is one of the most important teaching peculiarities in formation of personal attributes of a future highly-qualified professional, which form the basis of professional mobility and competitiveness. It is summarized that an interdisciplinary character of research work in the modern educational paradigm is aimed at solving innovative tasks of integrating educational, scientific and practice-oriented constituents in the context of the competency building approach.

  15. Methodological Approach Into Researching Traffic Under Extraordinary Security Circumstances

    Directory of Open Access Journals (Sweden)

    Peter-Anthony Ercegovac

    2008-09-01

    Full Text Available The complexity of researching traffic under extraordinaryconditions in order to implement a more efficient and functionaltraffic management strategy under both normal and irregularconditions- as well as the grey zone of when the changefrom normal into extraordinary traffic conditions actually occur-provides the researcher with numerous methodologicalproblems.Starting from the viewpoint that the field of traffic scienceneeds an increase into the capacity of research into traffic underextraordinary conditions we have chosen to define withinthis article a specific methodological approach that undertakesa study into the exposure, menace, threat and risk faced by trafficsystems under extraordinary conditions through utilisingmethods utilised by the military that allow for the possible resolutionof such problems through compatible testing of both simulatedand real life conditions that such systems may face.In searching for possible applicable solutions to such demandingparametres we believe that the use of concrete informationin real time and real space in order to bring about amore efficient functioning of traffic under extraordinary conditionscan be achieved through the use of the analytical capacityof traffic systems information gathering attained through theusage of Uninhabited Flying Vehicles (UFVs in monitoringroad, rail and maritime traffic and transport.

  16. Trends in Singing Voice Research: An Innovative Approach.

    Science.gov (United States)

    Pestana, Pedro Melo; Vaz-Freitas, Susana; Manso, Maria Conceição

    2018-01-11

    The objectives of this study were to trace and describe research patterns in singing voice, to compare the amount of published research over time, to identify journals that published most papers on "singing voice," and to establish the most frequent research topics. The study uses qualitative and quantitative approaches through descriptive statistics, text mining, and clustering. The authors conducted a search to identify scientific papers. The titles and abstracts were analyzed regarding word frequency and relations between them, through hierarchical cluster analysis and co-occurrence networks. The frequency of journals was calculated, as well as the amount of papers across time. Since 1949, 754 papers were published and an increase was noticed. Even though 162 journals were identified by the authors, the Journal of Voice holds the majority of papers, in every analyzed period. An evolution of studied topics is described. Up to 2010, the main theme was professional singers, especially classical and opera interpreters. Since then, voice quality and the effects of training gathered more attention. The growing interest in singing has been conspicuous since the first indexed paper. However, it has been slightly slowing down. Until 2010, great importance was given to the voice quality of singers and their occupational demands. Acoustic analysis was widely used to study the effects of training. Since 2010, the concern with functionality is increasing, rather than the organic voice structures. Musical perception studies have been a trend, as well as the use of electroglottography. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  17. Computerized tablet based versus traditional paper- based survey methods: results from adolescent's health research in schools of Maharashtra, India

    OpenAIRE

    Naveen Agarwal; Balram Paswan; Prakash H. Fulpagare; Dhirendra N Sinha; Thaksaphon Thamarangsi; Manju Rani

    2018-01-01

    Background and challenges to implementation Technological advancement is growing very fast in India and majority of young population is handling electronic devices often during leisure as well as at work. This study indicates that electronic tablets are less time consuming and improves survey response rate over the traditional paper-pencil survey method. Intervention or response An Android-based Global School-based Health Survey (GSHS) questionnaire was used with the...

  18. A Partnership Approach to Promoting Information Literacy for Higher Education Researchers

    Directory of Open Access Journals (Sweden)

    Stéphane Goldstein

    2012-01-01

    Full Text Available The promotion of information literacy in the UK higher education research sector has traditionally been the preserve of academic libraries. However, other professional groups have obvious interests in this area, and there is a strong case for providing a framework which enables different parties with a stake in information literacy to work together in order to reach practical objectives. In the UK, a coalition of partners has been set up to provide this collective framework and to provide synergy. This paper sets out the rationale for this approach, sets out the sort of activities that the coalition has fostered since its inception in late 2009 and reflects on whether it might serve as an example for other parts of Europe or for transnational collaborations.

  19. The research for the clinical curative effect through combing traditional Chinese medicine with insulin to cure diabetes.

    Science.gov (United States)

    Wu, Qianfeng; Fan, Hongxia

    2014-07-01

    The clinical curative effect is observed through curing type 2 diabetes mellitus with the therapy of combing Traditional Chinese Medicine (TCM) with insulin. Both the insulin prescription and the treatment of traditional Chinese medicine prescription are applied as mutual comparison. And the dosage, time, blood sugar level and curative effect etc are recorded. Healthy human body is taken as comparison for monitoring physical indicators. Through comparing insulin prescription and the combing therapy of insulin and traditional Chinese medicine, the insulin treatment group is better than contrast group (Pblending use group, the ISI in each group is significantly lower than that of health control group (P<0.01), where accumulation of damp heat in spleen type is the lowest; the BM I, H bA1C of type 2 diabetic patient is higher than health control group, its accumulation of damp heat in spleen type is the highest, TC, TG typical accumulation of damp heat in spleen are higher than other pattern of syndrome. the treatment method of combing TCM with insulin in curing type 2 diabetes mellitus has better effect than using insulin treatment alone; the resistance degree of insulin demonstrates the changing trend of first increase and later decrease with the development of disease course. Accumulation of damp heat in spleen type accounts for the highest proportion in type 2 diabetic patients, and there exists serious insulin resistance.

  20. A Dialectical Approach to Theoretical Integration in Developmental-Contextual Identity Research

    Science.gov (United States)

    Seaman, Jayson; Sharp, Erin Hiley; Coppens, Andrew D.

    2017-01-01

    Future advances in identity research will depend on integration across major theoretical traditions. Developmental-contextualism has established essential criteria to guide this effort, including specifying the context of identity development, its timing over the life course, and its content. This article assesses 4 major traditions of identity…

  1. Approaches in Synesthesia Research: Neurocognitive Aspects and Diagnostic Criteria

    Directory of Open Access Journals (Sweden)

    Nina Mikus

    2013-10-01

    Full Text Available Synesthesia is a fairly rare phenomenon in which the subject in contact with certain stimulus in one modality experiences unusual extra sensations in other modalities, such as seeing or feeling colours while listening to music or personifying of letters and numbers. The phenomenon was long perceived to be merely a product of imagination and associations. Latest research, however, is based on a multidisciplinary approach, which includes first-hand synesthetic reports, neuroimaging and behavioural tests used in confirming and explaining the phenomenon’s presence as well as its neurophysiological foundations. This article presents an overview of such investigations through the lens of cognitive and psychophysical paradigms, neural models and genetic studies of synesthesia.

  2. Study Of Lampungnese Traditional Home Garden Design

    Science.gov (United States)

    Pratiwi, R. A.; Gunawan

    2017-10-01

    Lampung is one area in Indonesia which has a traditional culture that comes from two groups of descents, they are ulun Lampung Pepadun and ulun Lampung Saibatin. Lampungnese traditional culture has been well-known by Indonesian people for its traditional dances, traditional clothing, or traditional home architecture. However, Lampungnese traditional home garden recently may not yet been described. Information related to Lampungnese traditional home garden is still very limited and it does not yet represented the culture based design concept. This research was directed to identify the elements of the home garden and map it into design concept of the Lampungnese traditional home garden based on information of Lampungnese traditional culture. The study was conducted by using descriptive approach through literature review, interviews and cultural exploration, as well as field observation. The study was able to identify the elements forming the Lampungnese traditional home garden, namely gakhang hadap, walai, outdoor kitchenette, firewood place, outdoor kitchen, livestock barns, as well as plants. Space layout of the home garden comprises front yard (tengahbah/terambah/beruan), side yard (kebik/kakebik), and backyard (kudan/juyu/kebon). Each element of the garden is located in the right place of the space layout.

  3. Antimicrobial Approaches for Textiles: From Research to Market

    Directory of Open Access Journals (Sweden)

    Diana Santos Morais

    2016-06-01

    Full Text Available The large surface area and ability to retain moisture of textile structures enable microorganisms’ growth, which causes a range of undesirable effects, not only on the textile itself, but also on the user. Due to the public health awareness of the pathogenic effects on personal hygiene and associated health risks, over the last few years, intensive research has been promoted in order to minimize microbes’ growth on textiles. Therefore, to impart an antimicrobial ability to textiles, different approaches have been studied, being mainly divided into the inclusion of antimicrobial agents in the textile polymeric fibers or their grafting onto the polymer surface. Regarding the antimicrobial agents, different types have been used, such as quaternary ammonium compounds, triclosan, metal salts, polybiguanides or even natural polymers. Any antimicrobial treatment performed on a textile, besides being efficient against microorganisms, must be non-toxic to the consumer and to the environment. This review mainly intends to provide an overview of antimicrobial agents and treatments that can be performed to produce antimicrobial textiles, using chemical or physical approaches, which are under development or already commercially available in the form of isolated agents or textile fibers or fabrics.

  4. [Ethnographic approaches to research and intervention in mental health].

    Science.gov (United States)

    Nunes, Mônica de Oliveira; de Torrenté, Maurice

    2013-10-01

    The specifics of ethnographic approaches to mental health research are examined, highlighting the motives why the type of knowledge produced by ethnography is relevant to the context of Psychiatric Reform and the biomedicalization of existence. The discussion is focused on interpretation-based ethnography in the field of mental health, stressing the theoretical and methodological foundations of a comprehensive form of apprehending the scope of mental health as an object akin to a clinic of the individual. The centrality of social and cultural aspects in the ethnographic approach and the inflexions mediated by the type of ethnographic methodological undertaking is stressed. Lastly, the ethnography of madness is seen as a fitting example that substantiates some of these characteristics. The contention is that accessing psychotic persons (and others who may speak about these experiences) from varied areas of their daily life, situated in their various social inscriptions, while confronting these interpretations with other interpretative dimensions of their social reality and within the logic linked to local psychologies, is a pertinent procedure, from whence certain aspects of an understanding of madness (or causes of its incomprehension) can emerge.

  5. An alternative approach for socio-hydrology: case study research

    Science.gov (United States)

    Mostert, Erik

    2018-01-01

    Currently the most popular approach in socio hydrology is to develop coupled human-water models. This article proposes an alternative approach, qualitative case study research, involving a systematic review of (1) the human activities affecting the hydrology in the case, (2) the main human actors, and (3) the main factors influencing the actors and their activities. Moreover, this article presents a case study of the Dommel Basin in Belgium and the Netherlands, and compares this with a coupled model of the Kissimmee Basin in Florida. In both basins a pendulum swing from water resources development and control to protection and restoration can be observed. The Dommel case study moreover points to the importance of institutional and financial arrangements, community values, and broader social, economic, and technical developments. These factors are missing from the Kissimmee model. Generally, case studies can result in a more complete understanding of individual cases than coupled models, and if the cases are selected carefully and compared with previous studies, it is possible to generalize on the basis of them. Case studies also offer more levers for management and facilitate interdisciplinary cooperation. Coupled models, on the other hand, can be used to generate possible explanations of past developments and quantitative scenarios for future developments. The article concludes that, given the limited attention they currently get and their potential benefits, case studies deserve more attention in socio-hydrology.

  6. Need of the regulation for profit percentage investment by pharmaceutical companies in new drug discovery research from the various local traditional medicinal and plant systems.

    Science.gov (United States)

    Bhattarai, M D

    2012-01-01

    In the modern medical systems the active pharmacological ingredients, effective against any disease is identified, purified and studied for its various effects and side-effects whereas it is not so in the traditional systems. Therefore, it is not surprising that safety concerns have often been raised about the traditional medical products. The major issue now, is to make appropriate situation with basic supports to bring all the available experts and resources together for the identification, purification, and study of efficacy and safety of the active molecules of the popular traditional medicines. Government and public sectors in the countries with such rich traditional medicinal and plant systems have related experts, but they also have much hurdle regarding recruitment and retention of expert human resources, getting fund, purchase and maintenance of equipment, bureaucratic formalities and others. The pharmaceutical companies have basic laboratories with related infrastructure and human resources as well as interest about bringing the drug molecules. To bridge the gap, there is a need of the regulation which will make the pharmaceutical companies to invest certain percentage of their profit in the field of research to identify new drug molecules and to study their effects. It is just not an issue of discovering the active molecule but also of creating the concept and culture of research, purity and quality of drugs, safety of people, and future direction of the human society.

  7. Rethinking Physics for Biologists: A design-based research approach

    Science.gov (United States)

    Sawtelle, Vashti

    2015-03-01

    Biology majors at the University of Maryland are required to take courses in biology, chemistry, and physics - but they often see these courses as disconnected. Over the past three years the NEXUS/Physics course has been working to develop an interdisciplinary learning environment that bridges the disciplinary domains of biology and physics. Across the three years we have gone from teaching in a small class with one instructor to teaching in a large lecture hall with multiple instructors. We have used a design-based research approach to support critical reflection of the course at multiple-time scales. In this presentation I will detail our process of collecting systematic data, listening to and valuing students' reasoning, and bridging diverse perspectives led. I will demonstrate how this process led to improved curricular design, refined assessment objectives, and new design heuristics. This work is supported by NSF-TUES DUE 11-22818, the HHMI NEXUS grant, and a NSF Graduate Research Fellowship (DGE 0750616).

  8. The Threat of Uncertainty: Why Using Traditional Approaches for Evaluating Spacecraft Reliability are Insufficient for Future Human Mars Missions

    Science.gov (United States)

    Stromgren, Chel; Goodliff, Kandyce; Cirillo, William; Owens, Andrew

    2016-01-01

    Through the Evolvable Mars Campaign (EMC) study, the National Aeronautics and Space Administration (NASA) continues to evaluate potential approaches for sending humans beyond low Earth orbit (LEO). A key aspect of these missions is the strategy that is employed to maintain and repair the spacecraft systems, ensuring that they continue to function and support the crew. Long duration missions beyond LEO present unique and severe maintainability challenges due to a variety of factors, including: limited to no opportunities for resupply, the distance from Earth, mass and volume constraints of spacecraft, high sensitivity of transportation element designs to variation in mass, the lack of abort opportunities to Earth, limited hardware heritage information, and the operation of human-rated systems in a radiation environment with little to no experience. The current approach to maintainability, as implemented on ISS, which includes a large number of spares pre-positioned on ISS, a larger supply sitting on Earth waiting to be flown to ISS, and an on demand delivery of logistics from Earth, is not feasible for future deep space human missions. For missions beyond LEO, significant modifications to the maintainability approach will be required.Through the EMC evaluations, several key findings related to the reliability and safety of the Mars spacecraft have been made. The nature of random and induced failures presents significant issues for deep space missions. Because spare parts cannot be flown as needed for Mars missions, all required spares must be flown with the mission or pre-positioned. These spares must cover all anticipated failure modes and provide a level of overall reliability and safety that is satisfactory for human missions. This will require a large amount of mass and volume be dedicated to storage and transport of spares for the mission. Further, there is, and will continue to be, a significant amount of uncertainty regarding failure rates for spacecraft

  9. International health research monitoring: exploring a scientific and a cooperative approach using participatory action research.

    Science.gov (United States)

    Chantler, Tracey; Cheah, Phaik Yeong; Miiro, George; Hantrakum, Viriya; Nanvubya, Annet; Ayuo, Elizabeth; Kivaya, Esther; Kidola, Jeremiah; Kaleebu, Pontiano; Parker, Michael; Njuguna, Patricia; Ashley, Elizabeth; Guerin, Philippe J; Lang, Trudie

    2014-02-17

    To evaluate and determine the value of monitoring models developed by the Mahidol Oxford Tropical Research Unit and the East African Consortium for Clinical Research, consider how this can be measured and explore monitors' and investigators' experiences of and views about the nature, purpose and practice of monitoring. A case study approach was used within the context of participatory action research because one of the aims was to guide and improve practice. 34 interviews, five focus groups and observations of monitoring practice were conducted. Fieldwork occurred in the places where the monitoring models are coordinated and applied in Thailand, Cambodia, Uganda and Kenya. Participants included those coordinating the monitoring schemes, monitors, senior investigators and research staff. Transcribed textual data from field notes, interviews and focus groups was imported into a qualitative data software program (NVIVO V. 10) and analysed inductively and thematically by a qualitative researcher. The initial coding framework was reviewed internally and two main categories emerged from the subsequent interrogation of the data. The categories that were identified related to the conceptual framing and nature of monitoring, and the practice of monitoring, including relational factors. Particular emphasis was given to the value of a scientific and cooperative style of monitoring as a means of enhancing data quality, trust and transparency. In terms of practice the primary purpose of monitoring was defined as improving the conduct of health research and increasing the capacity of researchers and trial sites. The models studied utilise internal and network wide expertise to improve the ethics and quality of clinical research. They demonstrate how monitoring can be a scientific and constructive exercise rather than a threatening process. The value of cooperative relations needs to be given more emphasis in monitoring activities, which seek to ensure that research protects

  10. A Proteomic Approach for the Diagnosis of ‘Oketsu’ (blood stasis, a Pathophysiologic Concept of Japanese Traditional (Kampo Medicine

    Directory of Open Access Journals (Sweden)

    Chinami Matsumoto

    2008-01-01

    Full Text Available ‘Oketsu’ is a pathophysiologic concept in Japanese traditional (Kampo medicine, primarily denoting blood stasis/stagnant syndrome. Here we have explored plasma protein biomarkers and/or diagnostic algorithms for ‘Oketsu’. Sixteen rheumatoid arthritis (RA patients were treated with keishibukuryogan (KBG, a representative Kampo medicine for improving ‘Oketsu’. Plasma samples were diagnosed as either having an ‘Oketsu’ (n = 19 or ‘non-Oketsu’ (n = 29 state according to Terasawa's ‘Oketsu’ scoring system. Protein profiles were obtained by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS and hierarchical clustering and decision tree analyses were performed. KBG treatment for 4 or 12 weeks decreased the ‘Oketsu’ scores significantly. SELDI protein profiles gave 266 protein peaks, whose expression was significantly different between the ‘Oketsu’ and ‘non-Oketsu’ states. Hierarchical clustering gave three major clusters (I, II, III. The majority (68.4% of ‘Oketsu’ samples were clustered into one cluster as the principal component of cluster I. The remaining ‘Oketsu’ profiles constituted a minor component of cluster II and were all derived from patients cured of the ‘Oketsu’ state at 12 weeks. Construction of the decision tree addressed the possibility of developing a diagnostic algorithm for ‘Oketsu’. A reduction in measurement/pre-processing conditions (from 55 to 16 gave a similar outcome in the clustering and decision tree analyses. The present study suggests that the pathophysiologic concept of Kampo medicine ‘Oketsu’ has a physical basis in terms of the profile of blood proteins. It may be possible to establish a set of objective criteria for diagnosing ‘Oketsu’ using a combination of proteomic and bioinformatics-based classification methods.

  11. Three approaches in the research field of ethnomodeling: emic (local, etic (global, and dialogical (glocal

    Directory of Open Access Journals (Sweden)

    Daniel C. Orey

    2015-07-01

    Full Text Available The acquisition of both emic (local and etic (global knowledge is an alternative goal for the implementation of ethnomodeling research. Emic knowledge is essential for an intuitive and empathic understanding of mathematical ideas, procedures, and practices developed by the members of distinct cultural groups. It is essential for conducting effective ethnographic fieldwork. Furthermore, emic knowledge is a valuable source of inspiration for etic hypotheses. Etic knowledge is essential for cross-cultural comparisons, which are based on the components of ethnology. In this regard, such comparisons demand standard units and categories to facilitate communication. Dialogical (glocal is a third approach for ethnomodeling research that makes use of both emic and etic knowledge traditions through processes of dialogue and interaction. Ethnomodeling is defined as the study of mathematical phenomena within a culture because it is a social construct and is culturally bound. Finally, the objective of this article is to show how we have come to use a combination of emic, etic and dialogical (glocal approaches in our work in the area of ethnomodeling, which contributes to the acquisition of a more complete understanding of mathematical practices developed by the members of distinct cultural groups.

  12. Personal and professional influences on practitioners' attitudes to traditional and complementary approaches to health in the UK

    Directory of Open Access Journals (Sweden)

    Ava Lorenc

    2014-10-01

    Conclusions: Practitioners need to understand patients' diverse health beliefs and practices and discuss TCA with families, despite regulatory and organizational constraints, to fulfil their professional duty to patients, particularly regarding safety. Further research is needed to verify the professional socialization process and the influence of specific regulation on training.

  13. The pitfalls of capital budgeting : when costs correlate to oil price. Is the real-options approach superior to traditional valuation?

    Energy Technology Data Exchange (ETDEWEB)

    Schiozer, R.F. [Getulio Vargas Foundation, Sao Paolo (Brazil). School of Administration de Empresas; Costa Lima, G.A.; Suslick, S.B. [Unicamp, Campinas (Brazil). Center of Petroleum Studies

    2007-07-01

    Due to increased demand for drilling rigs, specialized labor force and other resources, the costs of exploration, appraisal, development and production have significantly risen over the last five years. The change in costs has mostly been attributed to the increased activity in the oil and gas exploration and production (EP) industry, as a result of the increase in oil prices. It was hypothesized that operating costs in the EP industry were strongly correlated to the price of oil. However, the correlation between prices and costs has traditionally been overlooked in the capital budgeting process. This paper investigated the economic relationship between oil price and the operating costs in the EP industry. It also explored its implications for the capital budgeting process and decision-making. The paper demonstrated the evaluation of projects under traditional net present value (NPV) and real-option approaches. Empirical evidence was also provided on how costs correlated to oil prices. The differences between project valuation when cost-price correlation was taken into account or not was also discussed. Last, findings, conclusions and general implications of the results obtained for the decision-making process were identified. It was concluded that there was a positive correlation between price and operating costs, and that overlooking this relationship would have significant implications on the valuation of investment projects, both using a traditional NPV methodology, which resulted in undervalued projects, and under real option analysis, which resulted in overvaluing projects. 6 refs., 2 tabs., 5 figs.

  14. The pitfalls of capital budgeting : when costs correlate to oil price. Is the real-options approach superior to traditional valuation?

    International Nuclear Information System (INIS)

    Schiozer, R.F.; Costa Lima, G.A.; Suslick, S.B.

    2007-01-01

    Due to increased demand for drilling rigs, specialized labor force and other resources, the costs of exploration, appraisal, development and production have significantly risen over the last five years. The change in costs has mostly been attributed to the increased activity in the oil and gas exploration and production (EP) industry, as a result of the increase in oil prices. It was hypothesized that operating costs in the EP industry were strongly correlated to the price of oil. However, the correlation between prices and costs has traditionally been overlooked in the capital budgeting process. This paper investigated the economic relationship between oil price and the operating costs in the EP industry. It also explored its implications for the capital budgeting process and decision-making. The paper demonstrated the evaluation of projects under traditional net present value (NPV) and real-option approaches. Empirical evidence was also provided on how costs correlated to oil prices. The differences between project valuation when cost-price correlation was taken into account or not was also discussed. Last, findings, conclusions and general implications of the results obtained for the decision-making process were identified. It was concluded that there was a positive correlation between price and operating costs, and that overlooking this relationship would have significant implications on the valuation of investment projects, both using a traditional NPV methodology, which resulted in undervalued projects, and under real option analysis, which resulted in overvaluing projects. 6 refs., 2 tabs., 5 figs

  15. Diversity trends in bread wheat in Italy during the 20th century assessed by traditional and multivariate approaches.

    Science.gov (United States)

    Ormoli, Leonardo; Costa, Corrado; Negri, Stefano; Perenzin, Maurizio; Vaccino, Patrizia

    2015-02-25

    A collection of 157 Triticum aestivum accessions, representative of wheat breeding in Italy during the 20(th) century, was assembled to describe the evolutionary trends of cultivated varieties throughout this period. The lines were cultivated in Italy, in two locations, over two growing seasons, and evaluated for several agronomical, morphological and qualitative traits. Analyses were conducted using the most common univariate approach on individual plant traits coupled with a correspondance multivariate approach. ANOVA showed a clear trend from old to new varieties, leading towards earliness, plant height reduction and denser spikes with smaller seeds. The average protein content gradually decreased over time; however this trend did not affect bread-making quality, because it was counterbalanced by a gradual increase of SDS sedimentation volume, achieved by the incorporation of favourable alleles into recent cultivars. Correspondence analysis allowed an overall view of the breeding activity. A clear-cut separation was observed between ancient lines and all the others, matched with a two-step gradient, the first, corresponding roughly to the period 1920-1940, which can be ascribed mostly to genetics, the second, from the 40s onward, which can be ascribed also to the farming practice innovations, such as improvement of mechanical devices and optimised use of fertilizers.

  16. Panorama of Reconstruction of Skull Base Defects: From Traditional Open to Endonasal Endoscopic Approaches, from Free Grafts to Microvascular Flaps

    Science.gov (United States)

    Reyes, Camilo; Mason, Eric; Solares, C. Arturo

    2014-01-01

    Introduction A substantial body of literature has been devoted to the distinct characteristics and surgical options to repair the skull base. However, the skull base is an anatomically challenging location that requires a three-dimensional reconstruction approach. Furthermore, advances in endoscopic skull base surgery encompass a wide range of surgical pathology, from benign tumors to sinonasal cancer. This has resulted in the creation of wide defects that yield a new challenge in skull base reconstruction. Progress in technology and imaging has made this approach an internationally accepted method to repair these defects. Objectives Discuss historical developments and flaps available for skull base reconstruction. Data Synthesis Free grafts in skull base reconstruction are a viable option in small defects and low-flow leaks. Vascularized flaps pose a distinct advantage in large defects and high-flow leaks. When open techniques are used, free flap reconstruction techniques are often necessary to repair large entry wound defects. Conclusions Reconstruction of skull base defects requires a thorough knowledge of surgical anatomy, disease, and patient risk factors associated with high-flow cerebrospinal fluid leaks. Various reconstruction techniques are available, from free tissue grafting to vascularized flaps. Possible complications that can befall after these procedures need to be considered. Although endonasal techniques are being used with increasing frequency, open techniques are still necessary in selected cases. PMID:25992142

  17. Towards a Shift in Perspective for Inclusive Education Research--A Continental Approach

    Science.gov (United States)

    Korsgaard, Morten Timmermann; Mortensen, Stig Skov

    2017-01-01

    With a starting point in the tradition of "geisteswissenschaftliche Pädagogik," this article presents a challenge to inclusive education research to engage a Continental perspective on educational research. The motivation is to entice inclusive education researchers to begin to ask educational questions of inclusion, as opposed to…

  18. CURRENT APPROACHES FOR RESEARCH OF MULTIPLE SCLEROSIS BIOMARKERS

    Directory of Open Access Journals (Sweden)

    Kolyada T.I

    2016-12-01

    Full Text Available Current data concerning features of multiple sclerosis (MS etiology, pathogenesis, clinical course and treatment of disease indicate the necessity of personalized approach to the management of MS patients. These features are the variety of possible etiological factors and mechanisms that trigger the development of MS, different courses of disease, and significant differences in treatment efficiency. Phenotypic and pathogenetic heterogeneity of MS requires, on the one hand, the stratification of patients into groups with different treatment depending on a number of criteria including genetic characteristics, disease course, stage of the pathological process, and forms of the disease. On the other hand, it requires the use of modern methods for assessment of individual risk of developing MS, its early diagnosis, evaluation and prognosis of the disease course and the treatment efficiency. This approach is based on the identification and determination of biomarkers of MS including the use of systems biology technology platforms such as genomics, proteomics, metabolomics and bioinformatics. Research and practical use of biomarkers of MS in clinical and laboratory practice requires the use of a wide range of modern medical and biological, mathematical and physicochemical methods. The group of "classical" methods used to study MS biomarkers includes physicochemical and immunological methods aimed at the selection and identification of single molecular biomarkers, as well as methods of molecular genetic analysis. This group of methods includes ELISA, western blotting, isoelectric focusing, immunohistochemical methods, flow cytometry, spectrophotometric and nephelometric methods. These techniques make it possible to carry out both qualitative and quantitative assay of molecular biomarkers. The group of "classical methods" can also include methods based on polymerase chain reaction (including multiplex and allele-specific PCR and genome sequencing

  19. Research and Collaboration Overview of Institut Pasteur International Network: A Bibliometric Approach toward Research Funding Decisions

    Directory of Open Access Journals (Sweden)

    Ehsan Mostafavi

    2014-01-01

    Full Text Available Background Institut Pasteur International Network (IPIN, which includes 32 research institutes around the world, is a network of research and expertise to fight against infectious diseases. A scientometric approach was applied to describe research and collaboration activities of IPIN. Methods Publications were identified using a manual search of IPIN member addresses in Science Citation Index Expanded (SCIE between 2006 and 2011. Total publications were then subcategorized by geographic regions. Several scientometric indicators and the H-index were employed to estimate the scientific production of each IPIN member. Subject and geographical overlay maps were also applied to visualize the network activities of the IPIN members. Results A total number of 12667 publications originated from IPIN members. Each author produced an average number of 2.18 papers and each publication received an average of 13.40 citations. European Pasteur Institutes had the largest amount of publications, authored papers, and H-index values. Biochemistry and molecular biology, microbiology, immunology and infectious diseases were the most important research topics, respectively. Geographic mapping of IPIN publications showed wide international collaboration among IPIN members around the world. Conclusion IPIN has strong ties with national and international authorities and organizations to investigate the current and future health issues. It is recommended to use scientometric and collaboration indicators as measures of research performance in IPIN future policies and investment decisions.

  20. Research and collaboration overview of Institut Pasteur International Network: a bibliometric approach toward research funding decisions.

    Science.gov (United States)

    Mostafavi, Ehsan; Bazrafshan, Azam

    2014-01-01

    Institut Pasteur International Network (IPIN), which includes 32 research institutes around the world, is a network of research and expertise to fight against infectious diseases. A scientometric approach was applied to describe research and collaboration activities of IPIN. Publications were identified using a manual search of IPIN member addresses in Science Citation Index Expanded (SCIE) between 2006 and 2011. Total publications were then subcategorized by geographic regions. Several scientometric indicators and the H-index were employed to estimate the scientific production of each IPIN member. Subject and geographical overlay maps were also applied to visualize the network activities of the IPIN members. A total number of 12667 publications originated from IPIN members. Each author produced an average number of 2.18 papers and each publication received an average of 13.40 citations. European Pasteur Institutes had the largest amount of publications, authored papers, and H-index values. Biochemistry and molecular biology, microbiology, immunology and infectious diseases were the most important research topics, respectively. Geographic mapping of IPIN publications showed wide international collaboration among IPIN members around the world. IPIN has strong ties with national and international authorities and organizations to investigate the current and future health issues. It is recommended to use scientometric and collaboration indicators as measures of research performance in IPIN future policies and investment decisions.

  1. Re-Imagining "Bildung Zur Humanität": How I Developed the Dialogos Approach to Practical Philosophy through Action Inquiry Research

    Science.gov (United States)

    Helskog, Guro Hansen

    2015-01-01

    This paper presents an account of how I developed the Dialogos approach to practical philosophy through action inquiry research. The process of development is understood as a contribution to the reconstruction of the notion "Bildung zur Humanität" as an ideal in education. Core perspectives, traditions and purposes involved in the action…

  2. Women convicted of promoting prostitution of a minor are different from women convicted of traditional sexual offenses: a brief research report.

    Science.gov (United States)

    Cortoni, Franca; Sandler, Jeffrey C; Freeman, Naomi J

    2015-06-01

    Some jurisdictions have legally decreed that certain nonsexual offenses (e.g., promoting prostitution of a minor, arson, burglary) can be considered sexual offenses. Offenders convicted of these crimes can be subjected to sexual offender-specific social control policies such as registration, as well as be included in sexual offender research such as recidivism studies. No studies, however, have systematically examined differences and similarities between this new class of sexual offenders and more traditional sexual offenders. The current study used a sample of 94 women convicted of sexual offenses to investigate whether women convicted of promoting prostitution of a minor differed on demographic and criminogenic features from those convicted of more traditional sexual offenses. Results show that women convicted of promoting prostitution offenses have criminal histories more consistent with general criminality and exhibit more general antisocial features than women convicted of traditional sexual offenses. These results support the notion that the inclusion of legally defined sexual offenders with traditional ones obscures important differences in criminogenic features among these women. © The Author(s) 2014.

  3. 客家传统服饰刺绣图案%Research on embroidery patterns of Hakka's traditional costumes

    Institute of Scientific and Technical Information of China (English)

    刘运娟; 陈东生

    2012-01-01

    This overview introduces the classification, skills, forms and color of the embroidery patterns of Hakka's traditional costumes. In terms of the embroidery pattern subjects, they cover animals and plants, geometric figures, personage, characters and utensils. The skills of embroidery are divided into 27 kinds of stitches of 7 series; and main compositions of embroidery patterns include "borderline", "theme" and " symmetry". Sharp contrast of colors exists on patterns, having the tendency towards "popular" in aesthetics and "utilitarianism" in decoration. The patterns of Hakka traditional costumes present regional features in respect of composition, content, skill, and color, and possess with the aesthetic feeling of Han nationality in central plains of China.%从客家服饰刺绣图案的分类、刺绣技法、图案构成、色彩运用角度入手,总结出客家传统服饰刺绣图案按其表现题材可分为动植物、几何图纹、人物、文字、生活器物等5个大类;刺绣技法分为7个系列27种针法;图案构成以边缘式、主题式与对称式为主;服饰图案色彩对比强烈,具有尚“俗”审美情趣且倾向装饰功利性.认为客家传统服饰图案在构图、表现题材、技法、用色等方面呈现地域性特征,并且具有深沉的中原汉民族审美情感倾向.

  4. Is Collaborative, Community-Engaged Scholarship More Rigorous than Traditional Scholarship? On Advocacy, Bias, and Social Science Research

    Science.gov (United States)

    Warren, Mark R.; Calderón, José; Kupscznk, Luke Aubry; Squires, Gregory; Su, Celina

    2018-01-01

    Contrary to the charge that advocacy-oriented research cannot meet social science research standards because it is inherently biased, the authors of this article argue that collaborative, community-engaged scholarship (CCES) must meet high standards of rigor if it is to be useful to support equity-oriented, social justice agendas. In fact, they…

  5. The pluralistic water research concept - a new human-water system research approach

    Science.gov (United States)

    Evers, Mariele; Höllermann, Britta; Almoradie, Adrian; Taft, Linda; Garcia-Santos, Glenda

    2017-04-01

    Sustainable water resources management has been and still is a main challenge for decision makers even though for the past number of decades integrative approaches and concepts (e.g. Integrated Water Resources Management - IWRM) have been developed to address problems on floods, droughts, water quality, water quantity, environment and ecology. Although somehow these approaches are aiming to address water related problems in an integrative approach and to some extent include or involve society in the planning and management, they still lack some of the vital components in including the social dimensions and their interaction with water. Understanding these dynamics in a holistic way and how they are shaped by time and space may tackle these shortcomings and provide more effective and sustainable management solutions with respect to a set of potential present social actions and values as well as possible futures. This paper aims to discuss challenges to coherently and comprehensively integrate the social dimensions of different human-water concepts like IWRM, socio-hydrology and waterscape. Against this background it will develop criteria for an integrative approach and present a newly developed concept termed pluralistic water research (PWR) concept. PWR is not only a pluralistic but also an integrative and interdisciplinary approach to acknowledge the social and water dimensions and their interaction and dynamics by considering more than one perspective of a water-related issue, hereby providing a set of multiple (future) developments. Our PWR concept will be illustrated by a case study application of the Canary island La Gomera. Furthermore an outlook on further possible developments of the PWR concept will be presented and discussed.

  6. A Systems Biology Approach to Infectious Disease Research: Innovating the Pathogen-Host Research Paradigm

    Energy Technology Data Exchange (ETDEWEB)

    Aderem, Alan; Adkins, Joshua N.; Ansong, Charles; Galagan, James; Kaiser, Shari; Korth, Marcus J.; Law, G. L.; McDermott, Jason E.; Proll, Sean; Rosenberger, Carrie; Schoolnik, Gary; Katze, Michael G.

    2011-02-01

    The 20th century was marked by extraordinary advances in our understanding of microbes and infectious disease, but pandemics remain, food and water borne illnesses are frequent, multi-drug resistant microbes are on the rise, and the needed drugs and vaccines have not been developed. The scientific approaches of the past—including the intense focus on individual genes and proteins typical of molecular biology—have not been sufficient to address these challenges. The first decade of the 21st century has seen remarkable innovations in technology and computational methods. These new tools provide nearly comprehensive views of complex biological systems and can provide a correspondingly deeper understanding of pathogen-host interactions. To take full advantage of these innovations, the National Institute of Allergy and Infectious Diseases recently initiated the Systems Biology Program for Infectious Disease Research. As participants of the Systems Biology Program we think that the time is at hand to redefine the pathogen-host research paradigm.

  7. Traditional medicine and genomics

    Directory of Open Access Journals (Sweden)

    Kalpana Joshi

    2010-01-01

    Full Text Available ′Omics′ developments in the form of genomics, proteomics and metabolomics have increased the impetus of traditional medicine research. Studies exploring the genomic, proteomic and metabolomic basis of human constitutional types based on Ayurveda and other systems of oriental medicine are becoming popular. Such studies remain important to developing better understanding of human variations and individual differences. Countries like India, Korea, China and Japan are investing in research on evidence-based traditional medicines and scientific validation of fundamental principles. This review provides an account of studies addressing relationships between traditional medicine and genomics.

  8. Traditional medicine and genomics.

    Science.gov (United States)

    Joshi, Kalpana; Ghodke, Yogita; Shintre, Pooja

    2010-01-01

    'Omics' developments in the form of genomics, proteomics and metabolomics have increased the impetus of traditional medicine research. Studies exploring the genomic, proteomic and metabolomic basis of human constitutional types based on Ayurveda and other systems of oriental medicine are becoming popular. Such studies remain important to developing better understanding of human variations and individual differences. Countries like India, Korea, China and Japan are investing in research on evidence-based traditional medicines and scientific validation of fundamental principles. This review provides an account of studies addressing relationships between traditional medicine and genomics.

  9. Scientific-theoretical research approach to practical theology in ...

    African Journals Online (AJOL)

    All of them work with practical theological hermeneutics. The basic hermeneutic approach of Daniël Louw is widened with an integrated approach by Richard R. Osmer in which practical theology as a hermeneutic discipline also includes the empirical aspect which the action theory approach has contributed to the ...

  10. Understanding clinical reasoning in osteopathy: a qualitative research approach.

    Science.gov (United States)

    Grace, Sandra; Orrock, Paul; Vaughan, Brett; Blaich, Raymond; Coutts, Rosanne

    2016-01-01

    Clinical reasoning has been described as a process that draws heavily on the knowledge, skills and attributes that are particular to each health profession. However, the clinical reasoning processes of practitioners of different disciplines demonstrate many similarities, including hypothesis generation and reflective practice. The aim of this study was to understand clinical reasoning in osteopathy from the perspective of osteopathic clinical educators and the extent to which it was similar or different from clinical reasoning in other health professions. This study was informed by constructivist grounded theory. Participants were clinical educators in osteopathic teaching institutions in Australia, New Zealand and the UK. Focus groups and written critical reflections provided a rich data set. Data were analysed using constant comparison to develop inductive categories. According to participants, clinical reasoning in osteopathy is different from clinical reasoning in other health professions. Osteopaths use a two-phase approach: an initial biomedical screen for serious pathology, followed by use of osteopathic reasoning models that are based on the relationship between structure and function in the human body. Clinical reasoning in osteopathy was also described as occurring in a number of contexts (e.g. patient, practitioner and community) and drawing on a range of metaskills (e.g. hypothesis generation and reflexivity) that have been described in other health professions. The use of diagnostic reasoning models that are based on the relationship between structure and function in the human body differentiated clinical reasoning in osteopathy. These models were not used to name a medical condition but rather to guide the selection of treatment approaches. If confirmed by further research that clinical reasoning in osteopathy is distinct from clinical reasoning in other health professions, then osteopaths may have a unique perspective to bring to multidisciplinary

  11. Content of a novel online collection of traditional east African food habits (1930s-1960s): data collected by the Max-Planck-Nutrition Research Unit, Bumbuli, Tanzania.

    Science.gov (United States)

    Raschke, Verena; Oltersdorf, Ulrich; Elmadfa, Ibrahim; Wahlqvist, Mark L; Cheema, Birinder Sb; Kouris-Blazos, Antigone

    2007-01-01

    Knowledge of traditional African foods and food habits has been, and continues to be, systematically extirpated. With the primary intent of collating data for our online collection documenting traditional African foods and food habits (available at: www.healthyeatingclub.com/Africa/), we reviewed the Oltersdorf Collection, 75 observational investigations conducted throughout East Africa (i.e. Tanzania, Kenya, and Uganda) between the 1930s and 1960s as compiled by the Max Planck Nutrition Research Unit, formerly located in Bumbuli, Tanzania. Data were categorized as follows: (1) food availability, (2) chemical composition, (3) staple foods (i.e. native crops, cereals, legumes, roots and tubers, vegetables, fruits, spices, oils and fats, beverages, and animal foods), (4) food preparation and culture, and (5) nutrient intake and health status indicators. Many of the traditional foods identified, including millet, sorghum, various legumes, root and tubers, green leafy vegetables, plant oils and wild meats have known health benefits. Food preparatory practices during this period, including boiling and occasional roasting are superior to current practices which favor frying and deep-frying. Overall, our review and data extraction provide reason to believe that a diversified diet was possible for the people of East Africa during this period (1930s-1960s). There is a wealth of knowledge pertaining to traditional East African foods and food habits within the Oltersdorf Collection. These data are currently available via our online collection. Future efforts should contribute to collating and honing knowledge of traditional foods and food habits within this region, and indeed throughout the rest of Africa. Preserving and disseminating this knowledge may be crucial for abating projected trends for non-communicable diseases and malnutrition in Africa and abroad.

  12. Research design: qualitative, quantitative and mixed methods approaches Research design: qualitative, quantitative and mixed methods approaches Creswell John W Sage 320 £29 0761924426 0761924426 [Formula: see text].

    Science.gov (United States)

    2004-09-01

    The second edition of Creswell's book has been significantly revised and updated. The author clearly sets out three approaches to research: quantitative, qualitative and mixed methods. As someone who has used mixed methods in my research, it is refreshing to read a textbook that addresses this. The differences between the approaches are clearly identified and a rationale for using each methodological stance provided.

  13. Una aproximación al estado de la partería tradicional en Colombia An approach to the state of traditional midwifery in Colombia

    Directory of Open Access Journals (Sweden)

    Celmira Laza Vásquez

    2012-06-01

    Full Text Available En Colombia coexisten dos sistemas de atención del parto: el formal y el tradicional. El segundo sobrevive dada la baja cobertura de la atención de los eventos relacionados con la gestación, el parto y el puerperio por el sistema formal, y por factores de tipo cultural. Sin embargo, a pesar de la consolidación de la partería tradicional y la figura de la partera en las zonas rurales apartadas y las urbanas marginales, en el país persiste un desconocimiento científico de este evento que cobra trascendencia actual ya que es uno de los que interviene en la presentación de la mortalidad y morbilidad materna y perinatal. El presente artículo se propone discutir acerca de la necesidad del abordaje investigativo en el tema de la partería y la partera tradicional. Así, se presentan los escasos resultados de los avances investigativos en este tema, se plantean algunos saldos pendientes a responder desde investigación científica y el posible aporte que pudiera realizar la partería tradicional al mejoramiento de la salud de la mujer.In Colombia there are two systems of care delivery: the formal and traditional. The second is still in use because of the low health coverage associated with pregnancy, childbirth and the postpartum period provided by the proper system, and other cultural factors. However, despite the consolidation of traditional midwifery and existence of the midwife figure in remote rural areas and urban marginal in the country, the lack of scientific knowledge persist of this event; who takes current impact in the presentation of mortality and maternal and perinatal morbidity. This paper aims to discuss about the need for research addressing the issue of midwives and traditional birth attendant. It presents the few results of the research progress on this subject, we present some outstanding balances to respond from scientific research and the possible contribution that could perform the traditional midwives to improve the

  14. Keeping Tradition

    NARCIS (Netherlands)

    Zenhong, C.; Buwalda, P.L.

    2011-01-01

    Chinese dumplings such as Jiao Zi and Bao Zi are two of the popular traditional foods in Asia. They are usually made from wheat flour dough (rice flour or starch is sometimes used) that contains fillings. They can be steamed, boiled and fried and are consumed either as a main meal or dessert. As

  15. Comparison of a traditional with a new approach based on Graph Theory to vulnerability assessment to natural hazards: a study case on a socio-economic complex system

    Science.gov (United States)

    Arosio, Marcello; Martina, Mario L. V.

    2017-04-01

    The emergent behaviour of the contemporary complex, socio-technical and interconnected society makes the collective risk greater than the sum of the parts and this requires a holistic, systematic and integrated approach. Although there have been major improvements in recent years, there are still some limitation in term of a holistic approach that is able to include the emergent value hidden in the connections between exposed elements and the interactions between the different spheres of the multi-hazards, vulnerability, exposure and resilience. To deal with these challenges it is necessary to consider the connections between the exposed elements (e.g. populations, schools, hospital, etc.) and to quantify the relative importance of the elements and their interconnections (e.g. the need of injured people to go to hospital or children to school). In a system (e.g. road, hospital and ecological network, etc.), or in a System of System (e.g. socio-technical urban service), there are critical elements that, beyond the intrinsic vulnerability, can be characterized by greater or lower vulnerability because of their physical, geographical, cyber or logical connections. To this aim, we propose in this study a comparative analysis between traditional reductionist approach and a new holistic approach to vulnerability assessment to natural hazards. The analysis considers a study case of a socio-economic complex system through an innovative approach based on the properties of graph G=(N,L). A graph consists of two sets N (nodes) and L (links): the nodes represent the single exposed elements (physical, social, environmental, etc.) to a hazard, while the links (or connections) represent the interaction between the elements. The final goal is to illustrate an application of this innovative approach of integrated collective vulnerability assessment.

  16. Taking a Multi-pronged Approach to Expand the Reach of Climate Research Results

    Science.gov (United States)

    Hauser, R.; Unger, M.; Eastburn, T.; Rockwell, A.; Laursen, K. K.; National CenterAtmospheric Research

    2011-12-01

    Recognizing the importance of tailoring content to a variety of audiences, the National Center for Atmospheric Research (NCAR) takes a multi-pronged approach to expand the reach of climate research results. The center's communications and education and outreach teams leverage Web 1.0 and 2.0 functionality - Google searches, Twitter, Facebook, YouTube - as well as face-to-face interactions and traditional media outlets to ensure climate change messages effectively connect with multiple audiences. Key to these efforts, NCAR seeks to frame messages that emphasize cultural cognition, that is, in a manner that recognizes and resonates with different audiences' values and thus their identities. Among the basic communications approaches NCAR uses to engage the public are one-on-one interactions with the visiting public, which ranges from school children and tourists, to dignitaries and journalists. As an example, the NCAR Journalism Fellowship brings a competitively selected group of internatoinal journalists to NCAR. During a week-long visit and ongoing contact, journalists are provided with a close-up, nuanced view of the science and individuals working on the bigger-picture research that drives climate-related sound bites reported by the press. NCAR provides media training for its scientists, giving them tools and practice in effectively handling interviews for print, Web and radio outlets. The institution hosts public events like "Super Science Saturday," and NCAR staff participate in external activities such as school science fairs, community events and continuing education sessions. In addition to interactive displays that allow the public to "experience" science directly and informally, NCAR develops educational programs and curricula targeted to specific age groups and levels of expertise. We will explore the importance of analogies, images and anecdotes in explaining complicated subjects to such a varied set of audiences, and identify key concepts in simplifying

  17. Building a bridge for nursing education and clinical care in Taiwan--using action research and Confucian tradition to close the gap.

    Science.gov (United States)

    Yang, Wan-Ping; Chao, Co-Shi Chantal; Lai, Wei-Shu; Chen, Ching-Huey; Shih, Ya Lan; Chiu, Ge-Lin

    2013-03-01

    Nursing workplaces in Taiwan are unable to retain talent. An examination of this problem has revealed that the causes of this phenomenon are that nursing education fails to cultivate the skills that meet workplace requirements and that there are gap between nursing education and clinical practice. This paper is an action research that aims is to design educational programs that can close the gap between nursing education and clinical practice in Taiwan. In this action research project, 4 action cycles were used to design educational programs including concept mapping and focused discussion strategies. Participants were invited to join the research in three teaching hospitals and one university. Two groups of participants, student nurses (SN) and nursing staff personnel (NS), were sampled and invited to participate in the research. Participant observation, focus groups, and qualitative interviews were used to collect data. Qualitative data were not only profiled by content analysis, but they were also compared continuously between the two groups as well as between the 4 cycles. The qualitative data collected for the 135 participants were analysed. The themes of an effective nursing program were summarized. Many fundamental values of traditional Chinese education have gradually faded due to the Westernization of education. In this study, we discovered that Western educational models may play a critical role in improving traditionally taught nursing education programs. Copyright © 2012 Elsevier Ltd. All rights reserved.

  18. Arts-Based Research: Trojan Horses and Shibboleths. The Liabilities of a Hybrid Research Approach. "What Hath Eisner Wrought?"

    Science.gov (United States)

    Pariser, David

    2009-01-01

    The term "arts-based research" has been debated for some time now. In an article strongly in favor of this approach Bean (2007) identifies three species: "Research on the arts (italics in the original) (art history, visual and cultural studies, media studies etc.)...Research for the arts, refers to research into applied techniques, materials and…

  19. Community Partnered Research Ethics Training in Practice: A Collaborative Approach to Certification.

    Science.gov (United States)

    Yonas, Michael A; Jaime, Maria Catrina; Barone, Jean; Valenti, Shannon; Documét, Patricia; Ryan, Christopher M; Miller, Elizabeth

    2016-04-01

    This report describes the development and implementation of a tailored research ethics training for academic investigators and community research partners (CRP). The Community Partnered Research Ethics Training (CPRET) and Certification is a free and publicly available model and resource created by a university and community partnership to ensure that traditional and non-traditional research partners may study, define, and apply principles of human subjects' research. To date, seven academic and 34 CRP teams have used this highly interactive, engaging, educational, and relationship building process to learn human subjects' research and be certified by the University of Pittsburgh Institutional Review Board (IRB). This accessible, flexible, and engaging research ethics training process serves as a vehicle to strengthen community and academic partnerships to conduct ethical and culturally sensitive research. © The Author(s) 2016.

  20. An Undergraduate Research Experience that Integrates Traditional Field Mapping, LiDAR, and 3D Numerical Modeling: Applying Lessons from a Recent Report from the National Academies of Sciences, Engineering, and Medicine in an Intermediate-Level Tectonic Landscapes Course

    Science.gov (United States)

    Reinen, L. A.; Brenner, K.

    2017-12-01

    Ongoing efforts to improve undergraduate education in science, technology, engineering, and mathematics (STEM) fields focus on increasing active student participation and decreasing traditional lecture-based teaching. Undergraduate research experiences (UREs), which engage students in the work of STEM professionals, are an example of these efforts. A recent report from the National Academies of Sciences, Engineering and Medicine (Undergraduate Research Experiences for STEM Students: Successes, Challenges, and Opportunities; 2017) provides characteristics of UREs, and indicates that participation in UREs increases student interest and persistence in STEM as well as provides opportunities to broaden student participation in these fields. UREs offer an excellent opportunity to engage students in research using the rapidly evolving technologies used by STEM professionals. In the fall of 2016, students in the Tectonic Landscapes class at Pomona College participated in a course-based URE that combined traditional field mapping methods with analysis of high-resolution topographic data (LiDAR) and 3D numerical modeling to investigate questions of active local faulting. During the first ten weeks students developed skills in: creation of fault maps from both field observations (GPS included) and high-resolution digital elevation models (DEMs), assessment of tectonic activity through analyses of DEMs of hill slope diffusion models and geomorphic indices, and evaluation of fault geometry hypotheses via 3D elastic modeling. Most of these assignments were focused on a single research site. While students primarily used Excel, ArcMap, and Poly3D, no previous knowledge of these was required or assumed. Through this iterative approach, students used increasingly more complex methods as well as gained greater ownership of the research process with time. The course culminated with a 4-week independent research project in which each student investigated a question of their own

  1. Bioaccumulation of radionuclides in traditional Aboriginal foods from the Magela and Cooper Creek systems. Research Report 11

    Energy Technology Data Exchange (ETDEWEB)

    Martin, P.; Hancock, G.J.; Johnston, A.; Murray, A.S.

    1995-12-31

    Activity concentrations of the radionuclides {sup 210} Pb, {sup 210} Po, {sup 226} Ra, {sup 238} U, {sup 234} U {sup 232} Th and {sup 230} Th were measured in edible flesh of a number of traditional Aboriginal food items from the Magela and Cooper Creek systems in the tropical Northern Territory of Australia. Some results for {sup 227} Ac were also obtained. Food items studied were fish, buffalo, pig, magpie goose, filesnake, goanna, turtle, freshwater shrimp, freshwater crocodile and two types of plant roots. Water and soil activity concentrations were also measured to enable the calculation of concentration factors. For most edible flesh samples, activity concentrations followed the approximate order: {sup 210} Po >> [{sup 226} Ra {approx} {sup 210} Pb] > [{sup 234} U{approx}{sup 238} U] > [{sup 230} Th{approx}{sup 232} Th]. The {sup 210} Po/{sup 210} Pb activity ratio was particularly high (greater than 100) for pig flesh. The highest soft tissue activity concentration recorded was 45000 {+-} 2000 mBq/kg wet weight for {sup 210} Po in one sample of turtle liver. Concentration factors for fish species fall into three groups. Group 1 (bony bream and sleepy cod) had factors about five times higher than for Group 2 (eight other species including barramundi). Some smaller fish species (Group 3) are eaten whole and hence have relatively high concentration factors. Variability with location and season was small in comparison with inter-group variability. Measured factors for fish in groups 1 and 3 were generally significantly higher than IAEA default values. Factors for turtle flesh were similar to those for fish in group 1, but were about a factor of 10 higher for liver. Factors for magpie goose, filesnake, freshwater shrimp, goanna and crocodile flesh were also of the same order as for fish in groups 1 or 2. 37 refs., 57 tabs., 4 figs.

  2. New approaches to the economic evaluation of fusion research

    International Nuclear Information System (INIS)

    Hazelrigg, G.A.; Lietzke, K.R.

    1978-01-01

    The economic evaluation of fusion research to date has focussed on the benefits of essentially unlimited energy for future generations. In this paper it is shown that energy research in general, and fusion research in particular, also provides benefits in the short term, benefitting us today as well as future generations. Short-term benefits are the result of two distinct aspects of fusion research. First, fusion research provides information for decision making on both the continuing fusion research efforts and on other energy research programs. Second, fusion research provides an expectation of a future energy source thereby promoting accelerated consumption of existing fossil fuels today. Both short-term benefits can be quantitatively evaluated and both are quite substantial. Together, these short-term benefits form the primary economic rationale for fusion research

  3. Lecture Capturing: Its Effects on Students' Absenteeism, Performance, and Impressions in a Traditional Marketing Research Course

    Science.gov (United States)

    Dommeyer, Curt J.

    2017-01-01

    A quasiexperiment was conducted among marketing research students to determine the effects of lecture capturing (LC). One group of students (the LC group) was allowed access to video recordings of the class lectures whereas another group of students in a parallel class (the control group) was not given access to the recordings. When both groups…

  4. A call for a multifaceted approach to language learning motivation research: Combining complexity, humanistic, and critical perspectives

    Directory of Open Access Journals (Sweden)

    Julian Pigott

    2012-10-01

    Full Text Available In this paper I give an overview of recent developments in the L2 motivation field, in particular the movement away from quantitative, questionnaire-based methodologies toward smaller-scale qualitative studies incorporating concepts from complexity theory. While complexity theory provides useful concepts for exploring motivation in new ways, it has nothing to say about ethics, morality, ideology, politics, power or educational purpose. Furthermore, calls for its use come primarily from researchers from the quantitative tradition whose aim in importing this paradigm from the physical sciences appears to be to conceptualize and model motivation more accurately. The endeavor therefore remains a fundamentally positivist one. Rather than being embraced as a self-contained methodology, I argue that complexity theory should be used cautiously and prudently alongside methods grounded in other philosophical traditions. Possibilities abound, but here I suggest one possible multifaceted approach combining complexity theory, a humanisticconception of motivation, and a critical perspective.

  5. Framing design research for service orientation through PSS approaches

    DEFF Research Database (Denmark)

    Sakao, Tomohiko; Sandström, Gunilla Ölundh; Matzen, Detlef

    2009-01-01

    on the literature analysis, the authors present three crucial dimensions for service oriented design research, i.e. an offer dimension representing products and services, a provider dimension, and a customer/user dimension. In addition, three research targets are proposed; PSS-offer modelling, PSS development......, and PSS potential. Furthermore, several promising future research directions are identified. These include evaluating economic consequences or environmental benefits, establishing terminology, organizational issues, and developing methods and tools to support designers. The boundaries to other research...... fields are getting blurry and many aspects of other professionalisms must be taken into account. Thus, there is especially need in future research to open towards other research areas....

  6. Missing Data Approaches in eHealth Research: Simulation Study and a Tutorial for Nonmathematically Inclined Researchers

    NARCIS (Netherlands)

    Blankers, Matthijs; Koeter, Maarten W. J.; Schippers, Gerard M.

    2010-01-01

    Background: Missing data is a common nuisance in eHealth research: it is hard to prevent and may invalidate research findings. Objective: In this paper several statistical approaches to data "missingness" are discussed and tested in a simulation study. Basic approaches (complete case analysis, mean

  7. COST AND TIME ESTIMATES DURING THE SUPPLIER SELECTION OF AN INFORMATION SYSTEM FOR LEGAL AREA: A CASE STUDY COMPARING TRADITIONAL AND AGILE PROJECT APPROACHES

    Directory of Open Access Journals (Sweden)

    Vieira, G. L. S.

    2017-06-01

    Full Text Available Considering a direct correlation between projects requirements details levels and their performance, this paper aims to evaluate whether the adoption of more extensive and detailed cost, time and scope estimation processes based on both practices, traditional and agile, and executed concurrently with the supplier selection stage, could guarantee greater accuracy in these estimates, thus increasing project success rates. Based on a case study for the information system project implementation into the legal area of a large Brazilian company, five suppliers had their proposals analyzed and compared in terms of the costs and deadlines involved, as well as the project management processes used in theirs estimates. From the obtained results, it was possible to observe that not all companies follow, at least during the prospecting phase, their service proposals described management processes, according to the theory. Another important finding was that the proposals involving, at least partially, agile approach concepts, were more likely to justify their estimates. These proposals still presented lower values, whenever compared to those less adherents to the theoretical concepts, as those based on traditional concepts.

  8. Direct analysis in real time mass spectrometry and multivariate data analysis: a novel approach to rapid identification of analytical markers for quality control of traditional Chinese medicine preparation.

    Science.gov (United States)

    Zeng, Shanshan; Wang, Lu; Chen, Teng; Wang, Yuefei; Mo, Huanbiao; Qu, Haibin

    2012-07-06

    The paper presents a novel strategy to identify analytical markers of traditional Chinese medicine preparation (TCMP) rapidly via direct analysis in real time mass spectrometry (DART-MS). A commonly used TCMP, Danshen injection, was employed as a model. The optimal analysis conditions were achieved by measuring the contribution of various experimental parameters to the mass spectra. Salvianolic acids and saccharides were simultaneously determined within a single 1-min DART-MS run. Furthermore, spectra of Danshen injections supplied by five manufacturers were processed with principal component analysis (PCA). Obvious clustering was observed in the PCA score plot, and candidate markers were recognized from the contribution plots of PCA. The suitability of potential markers was then confirmed by contrasting with the results of traditional analysis methods. Using this strategy, fructose, glucose, sucrose, protocatechuic aldehyde and salvianolic acid A were rapidly identified as the markers of Danshen injections. The combination of DART-MS with PCA provides a reliable approach to the identification of analytical markers for quality control of TCMP. Copyright © 2012 Elsevier B.V. All rights reserved.

  9. Access and benefits sharing of genetic resources and associated traditional knowledge in northern Canada: understanding the legal environment and creating effective research agreements.

    Science.gov (United States)

    Geary, Janis; Jardine, Cynthia G; Guebert, Jenilee; Bubela, Tania

    2013-01-01

    Research in northern Canada focused on Aboriginal peoples has historically benefited academia with little consideration for the people being researched or their traditional knowledge (TK). Although this attitude is changing, the complexity of TK makes it difficult to develop mechanisms to preserve and protect it. Protecting TK becomes even more important when outside groups become interested in using TK or materials with associated TK. In the latter category are genetic resources, which may have commercial value and are the focus of this article. This article addresses access to and use of genetic resources and associated TK in the context of the historical power-imbalances in research relationships in Canadian north. Review. Research involving genetic resources and TK is becoming increasingly relevant in northern Canada. The legal framework related to genetic resources and the cultural shift of universities towards commercial goals in research influence the environment for negotiating research agreements. Current guidelines for research agreements do not offer appropriate guidelines to achieve mutual benefit, reflect unequal bargaining power or take the relationship between parties into account. Relational contract theory may be a useful framework to address the social, cultural and legal hurdles inherent in creating research agreements.

  10. Access and benefits sharing of genetic resources and associated traditional knowledge in northern Canada: understanding the legal environment and creating effective research agreements

    Directory of Open Access Journals (Sweden)

    Janis Geary

    2013-08-01

    Full Text Available Background. Research in northern Canada focused on Aboriginal peoples has historically benefited academia with little consideration for the people being researched or their traditional knowledge (TK. Although this attitude is changing, the complexity of TK makes it difficult to develop mechanisms to preserve and protect it. Protecting TK becomes even more important when outside groups become interested in using TK or materials with associated TK. In the latter category are genetic resources, which may have commercial value and are the focus of this article. Objective. This article addresses access to and use of genetic resources and associated TK in the context of the historical power-imbalances in research relationships in Canadian north. Design. Review. Results. Research involving genetic resources and TK is becoming increasingly relevant in northern Canada. The legal framework related to genetic resources and the cultural shift of universities towards commercial goals in research influence the environment for negotiating research agreements. Current guidelines for research agreements do not offer appropriate guidelines to achieve mutual benefit, reflect unequal bargaining power or take the relationship between parties into account. Conclusions. Relational contract theory may be a useful framework to address the social, cultural and legal hurdles inherent in creating research agreements.

  11. An Active-Learning Approach to Fostering Understanding of Research Methods in Large Classes

    Science.gov (United States)

    LaCosse, Jennifer; Ainsworth, Sarah E.; Shepherd, Melissa A.; Ent, Michael; Klein, Kelly M.; Holland-Carter, Lauren A.; Moss, Justin H.; Licht, Mark; Licht, Barbara

    2017-01-01

    The current investigation tested the effectiveness of an online student research project designed to supplement traditional methods (e.g., lectures, discussions, and assigned readings) of teaching research methods in a large-enrollment Introduction to Psychology course. Over the course of the semester, students completed seven assignments, each…

  12. Contrasts and effect sizes in behavioral research: a correlational approach

    National Research Council Canada - National Science Library

    Rosenthal, Robert; Rosnow, Ralph L; Rubin, Donald B

    2000-01-01

    .... Researchers, teachers of research methods, and graduate students will be familiar with the principles and procedures of contrast analysis but will also be introduced to a series of newly developed...

  13. A multi-faceted approach to research development (I) : Addressing ...

    African Journals Online (AJOL)

    In the second article, we discuss: management and support; mentoring; engagement with post-graduate programmes; incentives; resources; and creating research initiatives. The article is directed at novel researchers, senior staff engaged in post-graduate supervision, mentoring and research development, and HE ...

  14. A multi-faceted approach to research development (II): Supporting ...

    African Journals Online (AJOL)

    This article discusses a number of critical areas of research development that have been identified: addressing perceptions and myths about research; management and support; mentoring; engagement with postgraduate programmes; incentives; resources; and creating research initiatives. For each of these critical areas, ...

  15. New Themes and Approaches in Second Language Motivation Research.

    Science.gov (United States)

    Dornyei, Zoltan

    2001-01-01

    Provides an overview of the current themes and research directions in second language motivation research. Argues that the initial research inspiration and standard-setting empirical work on second language motivation originating from Canada has borne fruit by educating a new generation of international scholars who have created a colorful mixture…

  16. Beyond Traditional Newspaper Advertisement: Leveraging Facebook-Targeted Advertisement to Recruit Long-Term Smokers for Research

    OpenAIRE

    Carter-Harris, Lisa; Bartlett Ellis, Rebecca; Warrick, Adam; Rawl, Susan

    2016-01-01

    Background Smokers are a stigmatized population, but an important population to reach for the purpose of research. Therefore, innovative recruitment methods are needed that are both cost-effective and efficacious in recruiting this population. Objective The aim of the present article was to evaluate the feasibility of Facebook-targeted advertisement to recruit long-term smokers eligible for lung cancer screening for a descriptive, cross-sectional survey. Methods A social media recruitment cam...

  17. A Mixed Methods Approach to Equity and Justice Research: Insights from Research on Children's Reasoning About Economic Inequality.

    Science.gov (United States)

    Mistry, Rashmita S; White, Elizabeth S; Chow, Kirby A; Griffin, Katherine M; Nenadal, Lindsey

    2016-01-01

    Mixed methods research approaches are gaining traction across various social science disciplines, including among developmental scientists. In this chapter, we discuss the utility of a mixed methods research approach in examining issues related to equity and justice. We incorporate a brief overview of quantitative and qualitative monomethod research approaches in our larger discussion of the advantages, procedures, and considerations of employing a mixed methods design to advance developmental science from an equity and justice perspective. To better illustrate the theoretical and practical significance of a mixed methods research approach, we include examples of research conducted on children and adolescents' conceptions of economic inequality as one example of developmental science research with an equity and justice frame. © 2016 Elsevier Inc. All rights reserved.

  18. An “All Teach, All Learn” Approach to Research Capacity Strengthening in Indigenous Primary Health Care Continuous Quality Improvement

    Science.gov (United States)

    McPhail-Bell, Karen; Matthews, Veronica; Bainbridge, Roxanne; Redman-MacLaren, Michelle Louise; Askew, Deborah; Ramanathan, Shanthi; Bailie, Jodie; Bailie, Ross; Matthews, Veronica

    2018-01-01

    In Australia, Indigenous people experience poor access to health care and the highest rates of morbidity and mortality of any population group. Despite modest improvements in recent years, concerns remains that Indigenous people have been over-researched without corresponding health improvements. Embedding Indigenous leadership, participation, and priorities in health research is an essential strategy for meaningful change for Indigenous people. To centralize Indigenous perspectives in research processes, a transformative shift away from traditional approaches that have benefited researchers and non-Indigenous agendas is required. This shift must involve concomitant strengthening of the research capacity of Indigenous and non-Indigenous researchers and research translators—all must teach and all must learn. However, there is limited evidence about how to strengthen systems and stakeholder capacity to participate in and lead continuous quality improvement (CQI) research in Indigenous primary health care, to the benefit of Indigenous people. This paper describes the collaborative development of, and principles underpinning, a research capacity strengthening (RCS) model in a national Indigenous primary health care CQI research network. The development process identified the need to address power imbalances, cultural contexts, relationships, systems requirements and existing knowledge, skills, and experience of all parties. Taking a strengths-based perspective, we harnessed existing knowledge, skills and experiences; hence our emphasis on capacity “strengthening”. New insights are provided into the complex processes of RCS within the context of CQI in Indigenous primary health care. PMID:29761095

  19. Assessing quality in European educational research indicators and approaches

    CERN Document Server

    Åström, Fredrik; Hansen, Antje

    2014-01-01

    Competition-based models for research policy and management have an increasing influence throughout the research process, from attracting funding to publishing results. The introduction of quality control methods utilizing various forms of performance indicators is part of this development. The authors presented in this volume deal with the following questions: What counts as ‘quality’ and how can this be assessed? What are the possible side effects of current quality control systems on research conducted in the European Research Area, especially in the social sciences and the humanities?

  20. Operations Research Approaches to Asset Management in Freight Rail

    DEFF Research Database (Denmark)

    Gorman, Michael F.; Harrod, Steven

    2011-01-01

    This article describes operations research methodologies as they apply to asset management in freight rail. We describe state-of-the-art methods for locomotive, crew, railcar, line and yard planning and management. We conclude with emerging areas of research in rail.......This article describes operations research methodologies as they apply to asset management in freight rail. We describe state-of-the-art methods for locomotive, crew, railcar, line and yard planning and management. We conclude with emerging areas of research in rail....

  1. A Semantic Approach to Cross-Disciplinary Research Collaboration

    Directory of Open Access Journals (Sweden)

    Laurens De Vocht

    2012-11-01

    Full Text Available The latest developments in ICT, more specifically Social Media and Web 2.0 tools, facilitate the use of online services in research and education. This is also known as Research 2.0 and Technology Enhanced Learning. Web 2.0 tools are especially useful in cases where experts from different disciplines want to collaborate. We suggest an integrated method that embeds these services in research and learning processes, because it is a laborious task for researchers and learners to check and use all varying types of tools and services. We explain a flexible model that uses state-of-the-art semantic technologies to model both structured and unstructured research data. The research data is extracted from many online resources and Social Media. We implement learning objects as an abstraction of the semantically modeled research data. We propose an environment that improves the scientific research and learning process by allowing researchers to efficiently browse the information and concepts represented as learning objects.

  2. Recent research advances and ethno-botanical history of miang, a traditional fermented tea (Camellia sinensis var. assamica of northern Thailand

    Directory of Open Access Journals (Sweden)

    Chartchai Khanongnuch

    2017-09-01

    Full Text Available Miang is an ethnic fermented tea leaf (Camellia sinensis var. assamica from northern Thailand. It has a long history of sociocultural relationship with northern Thai people. Unlike other types of tea, miang is a unique product that is known as chewing tea or eating tea. In addition, it is also a specific food for traditional religious ceremonies and funerals. Although chewing of miang has become less popular among younger generations, there remains a demand for miang in specific areas of northern Thailand. The traditional fermentation mechanism for miang has not been well documented and the information is now being developed. Current studies indicated that the astringent miang possessed higher phenolic metabolites especially epigallocatechin gallate than the sour miang and fresh tea leaf used for making miang in general. The chemical constituents in miang are of interest and the scientific advances to understand and develop this ethnic tea product are rapidly emerging. Miang has many potential benefits and is proposed to be used for many applications such as foods, pharmaceuticals, and nutraceuticals. Other valuable chemical constituents have not yet been widely reported and require further research. The current understanding of miang has been developed from literature on historic and sociocultural relationships of miang, current evidence scientific evidence, and personal interviews with local miang producers. From the plantation areas close to miang production, physiological, chemical, and microbiological analysis of miang were undertaken and integrated with current scientific literature and community surveys to build an evolving body of new knowledge. This paper provides important historic background of miang and its ethno-botanical relationship with northern Thai people. Traditional production of miang and its chemical and physical properties make miang different from other fermented tea leaves. Therefore, this unique miang with ethnic roots

  3. Qualitative Audience Research: Toward an Integrative Approach to Reception.

    Science.gov (United States)

    Jensen, Klaus Bruhn

    1987-01-01

    Analyzes research about the mass communication audience and describes a theoretical and methodological framework for further empirical studies. Discusses the (1) explanatory value of qualitative research; (2) social and cultural implications of the reception process, with special reference to television; and (3) applications and social relevance…

  4. Approaching Ethical Reasoning in Nursing Research through a Communitarian Perspective.

    Science.gov (United States)

    Dresden, Elissa; McElmurry, Beverly J.; McCreary, Linda L.

    2003-01-01

    Case studies depict dilemmas in nursing research involving protection of community rights and community informed consent. Outlines research guidelines derived from communitarian ethical frameworks that consider beneficence, justice, and respect for autonomy in the context of community. (Contains 58 references.) (SK)

  5. Quantitative Approaches to Group Research: Suggestions for Best Practices

    Science.gov (United States)

    McCarthy, Christopher J.; Whittaker, Tiffany A.; Boyle, Lauren H.; Eyal, Maytal

    2017-01-01

    Rigorous scholarship is essential to the continued growth of group work, yet the unique nature of this counseling specialty poses challenges for quantitative researchers. The purpose of this proposal is to overview unique challenges to quantitative research with groups in the counseling field, including difficulty in obtaining large sample sizes…

  6. Intimate Inquiry: A Love-Based Approach to Qualitative Research

    Science.gov (United States)

    Laura, Crystal T.

    2016-01-01

    Academics have a hard time talking about the role of "love" in social research, and the lack of a working definition for its meaning only partly explains our difficulty. The more substantial barrier is our tendency to think about "research" not as a careful exploration of specific social, intellectual, or methodological…

  7. Teaching Historical Research Skills to Generation Y: One Instructor's Approach

    Science.gov (United States)

    Thaler, Valerie S.

    2013-01-01

    In this article, the author offers a summary of the major research assignment she has developed for HIST 100, as well as the successes and struggles she has had along the way. The project requires students to experience research as a difficult process that demands their patience, perseverance, and assiduousness. Group work in class clearly plays…

  8. A Strategy-Based Approach towards Optimising Research Output

    Science.gov (United States)

    Lues, L.

    2013-01-01

    The South African higher education fraternity has experienced an outflow of senior research capacity during the past decade, resulting in a large influx of younger and less-published academics. More emphasis is therefore placed on the role of the central institution in ensuring research output. The Faculty of Economic and Management Sciences at a…

  9. Mixed-methods approaches in health research in Nepal

    OpenAIRE

    Simkhada, Padam; Van Teijlingen, Edwin; Wasti, Sharada Prasad; Sathian, B.

    2014-01-01

    Combining and integrating a mixture of qualitative and quantitative methods in one single study is widely used in health and social care research in high-income countries. This editorial adds a few words of advice to the novice mixed-methods researcher in Nepal.

  10. Student Approaches to Learning and Studying. Research Monograph.

    Science.gov (United States)

    Biggs, John B.

    A common thread in contemporary research in student learning refers to the ways in which students go about learning. A theory of learning is presented that accentuates the interaction between the person and the situation. Research evidence implies a form of meta-cognition called meta-learning, the awareness of students of their own learning…

  11. A constructivist approach for teaching research methodology in construction management

    NARCIS (Netherlands)

    Hartmann, Andreas; Doree, Andries G.; Martin, Ludwig

    2010-01-01

    Construction Management (CM) is an acknowledged field of expertise and profession that requires students to research real world problems. To prepare the students for this task, many CM programs contain a Research Methodology (RM) course. However, after taking part in these courses, many students

  12. Bourdieu and Higher Education Research: A Bricolage Approach

    Science.gov (United States)

    Morrison, Andrew

    2017-01-01

    I argue for the continuing relevance of the Bourdieusian theoretical schema to research related to higher education. The paper discusses my use of Bourdieu in two research projects: an examination of the educational and occupational decision-making of final-year vocational A-level students; an analysis of the perceptions of final-year…

  13. An integrative approach of the marketing research and benchmarking

    Directory of Open Access Journals (Sweden)

    Moraru Gina-Maria

    2017-01-01

    Full Text Available The accuracy of the manager’s actions in a firm depends, among other things, on the accuracy of his/her information about all processes. At this issue, developing a marketing research is essential, because it provides information that represents the current situation in organization and on the market. Although specialists devote the marketing research exclusively to the organizational marketing function, practice has shown that it can be used in any other function of the company: production, finance, human resources, research and development. Firstly, the paper presents the opportunities to use the marketing research as a management tool in various stages of creative thinking. Secondly, based on a study made from secondary sources of economic literature, the paper draws a parallel between marketing research and benchmarking. Finally, the paper shows that creative benchmarking closes the management - marketing - creativity circle for the benefit of the organization and community.

  14. Statistical approaches to orofacial pain and temporomandibular disorders research

    CERN Document Server

    Manfredini, Daniele; Nardini, Luca Guarda; Carrozzo, Eleonora; Salmaso, Luigi

    2014-01-01

    This book covers the biostatistical methods utilized to interpret and analyze dental research in the areas of orofacial pain and temporomandibular disorders. It will guide practitioners in these fields who would like to interpret research findings or find examples on the design of clinical investigations. After an introduction dealing with the basic issues, the central sections of the textbook are dedicated to the different types of investigations in sight of specific goals researchers may have. The final section contains more elaborate statistical concepts for expert professionals. The field of orofacial pain and temporomandibular disorders is emerging as one of the most critical areas of clinical research in dentistry. Due to the complexity of clinical pictures, the multifactorial etiology, and the importance of psychosocial factors in all aspects of the TMD practice, clinicians often find it hard to appraise their modus operandi, and researchers must constantly increase their knowledge in epidemiology and ...

  15. Ethical genetic research in Indigenous communities: challenges and successful approaches.

    Science.gov (United States)

    McWhirter, Rebekah E; Mununggirritj, Djapirri; Marika, Dipililnga; Dickinson, Joanne L; Condon, John R

    2012-12-01

    Indigenous populations, in common with all populations, stand to benefit from the potential of genetic research to lead to improvements in diagnostic and therapeutic tools for a wide range of complex diseases. However, many Indigenous communities, especially ones that are isolated, are not included in genetic research efforts. This situation is largely a consequence of the challenges of ethically conducting genetic research in Indigenous communities and compounded by Indigenous peoples' negative past experiences with genetic issues. To examine ways of addressing these challenges, we review one investigation of a cancer cluster in remote Aboriginal communities in Arnhem Land, Australia. Our experiences demonstrate that genetic research can be both ethically and successfully conducted with Indigenous communities by respecting the authority of the community, involving community members, and including regular community review throughout the research process. Copyright © 2012 Elsevier Ltd. All rights reserved.

  16. Application of the System Approach to Financial Services Market Research

    Directory of Open Access Journals (Sweden)

    Dubyna Maksym V

    2016-08-01

    Full Text Available The article analyzes the nature of the financial services market by using the system approach methodology. In particular, the attention is focused on the already existing conceptual approaches to defining the nature of this market, their basic aspects are analyzed. The use of the system approach allowed to identify the essence of the financial services market as a single, complex system, which is proposed to be considered as an aggregate number of consumers and providers of financial services operating within a single economic space, their relationships emerging to meet different in their nature demands for financial services, with their interrelation being associated with movement of financial resources within this space and partially accompanied by processes of transformation of temporary free funds of economic entities into credit and investment resources. In the article the system components and the relationships between them are determined, the elements of the environment are identified and their relationship with the market for financial services described.

  17. Physician participation in clinical research and trials: issues and approaches

    Directory of Open Access Journals (Sweden)

    Sami F Shaban

    2011-03-01

    Full Text Available Sayeeda Rahman1, Md Anwarul Azim Majumder1, Sami F Shaban2, Nuzhat Rahman3, Moslehuddin Ahmed4, Khalid Bin Abdulrahman5, Urban JA D’Souza61Department of Clinical Sciences, School of Life Sciences, University of Bradford, West Yorkshire, Bradford, UK; 2Department of Medical Education, Faculty of Medicine and Health Sciences, UAE University, Al-Ain, United Arab Emirates; 3Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA; 4Department of Community Medicine, Uttara Adhunik Medical College, Dhaka, Bangladesh; 5Department of Family Medicine and Medical Education, College of Medicine, Al-Imam University, Riyadh, Saudi Arabia; 6Department of Post Graduate Studies, School of Medicine, University Malaysia Sabah, Kota Kinabalu, Sabah, MalaysiaAbstract: The rapid development of new drugs, therapies, and devices has created a dramatic increase in the number of clinical research studies that highlights the need for greater participation in research by physicians as well as patients. Furthermore, the potential of clinical research is unlikely to be reached without greater participation of physicians in research. Physicians face a variety of barriers with regard to participation in clinical research. These barriers are system- or organization-related as well as research- and physician-related. To encourage physician participation, appropriate organizational and operational infrastructures are needed in health care institutes to support research planning and management. All physicians should receive education and training in the fundamentals of research design and methodology, which need to be incorporated into undergraduate medical education and postgraduate training curricula and then reinforced through continuing medical education. Medical schools need to analyze current practices of teaching–learning and research, and reflect upon possible changes needed to develop a ‘student-focused teaching–learning and

  18. [Music therapy single case research--a qualitative approach].

    Science.gov (United States)

    Langenberg, M; Frommer, J; Tress, W

    1995-12-01

    A qualitative approach for describing music psychotherapy treatment is developed. For this purpose we employ the methodological principle of triangulation of perspectives (patient, therapist, independent observers, composers). Our approach is based on the concept of the resonator function describing the perceptive capacity of all participants for effective and relationship-referred significance of the work produced during the treatment. The qualitative method importing and extending the knowledge of the inner context of the case is illustrated by two musical improvisations from the treatment of a female patient suffering from chronic migraine.

  19. Social self-esteem: theoretical and methodological approaches to research

    Directory of Open Access Journals (Sweden)

    Usova E.N.

    2017-09-01

    Full Text Available The perspective of the analysis of the phenomenon of the social well-being of patients with chronic diseases from the standpoint of the sociology of medicine is proved. Modern approaches to the study of social well-being within the framework of sociological and psychological approaches are singled out. The importance of studying the levels of social well-being (institutional and individual is presented to explain the individual's chosen strategies of behavior in the disease situation. The vectors of operationalization of the category of social well-being within the sociology of medicine are indicated.

  20. [Traditional nostrum].

    Science.gov (United States)

    Sugiyama, Shigeru

    2006-01-01

    The commercialization of drugs started toward the end of Heian period (794-1192) when not only aristocrats and monks who were traditional patrons to drug makers, but also local clans and landlords who became powerful as a result of the disbanding of aristocratic manors accumulated enough wealth to spend money on medicine. Although traveling around the country was still a dangerous endeavor, merchants assembled groups to bring lucrative foreign drugs (mainly Chinese) to remote areas. The spread of commercial drugs to common people, however, did not happen until the early Edo period (1603-1867), when the so-called barrier system was installed nationwide to make domestic travel safe. Commercialization started in large cities and gradually spread to other areas. Many nostrums popular until recently appeared in the Genroku period (1688-1703) or later. Many such nostrums were all-cures, often consisting of such active ingredients as Saussureae radix, Agalloch, or Gambir. Even in the Edo period, many people living in agricultural or fishing villages, as well as those in the lower tier, were still poor. Much of the medication available to those people was therefore made of various plant or animal-derived substances that were traditionally used as folk medicines.