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Sample records for tr xanh trn

  1. Summary of field operations, well TRN-1

    International Nuclear Information System (INIS)

    Fritts, J.E.; Thomas, E.; McCord, J.P.

    1996-03-01

    TRN-1 was drilled near the SE corner of Kirtland Air Force Base to a depth of 510 feet. This well is in the Site-Wide Hydrogeologic Characterization task field program, which is part of Sandia's Environmental Restoration Project. After drilling, the borehole was logged, plugged to a depth of 352 ft, and completed as a monitoring well. Sand pack interval is from 305 to 352 ft and the screen interval is from 320 to 340 ft. During field operations, important subsurface geologic and hydrologic data were obtained (drill cuttings, geophysical logs of alluvial cover). Identification of the Abo formation in the subsurface will be useful. The subsurface hydrologic data will help define the local hydrostratigraphic framework within the bedrock. Future aquifer testing will be conducted for transmissivity, etc

  2. TrnL-trnF intergenetic spacer and trnL intron define major clades within Luzula and Juncus (Juncaceae): Importance of structural mutations

    Czech Academy of Sciences Publication Activity Database

    Drábková, Lenka; Kirschner, Jan; Vlček, Čestmír; Pačes, Václav

    2004-01-01

    Roč. 59, - (2004), s. 1-10 ISSN 0022-2844 R&D Projects: GA AV ČR KSK6005114; GA ČR GA206/02/0355; GA MŠk(CZ) LN00A079 Institutional research plan: CEZ:AV0Z6005908 Keywords : Luzula * Juncus * trnL-trnF Subject RIV: EF - Botanics Impact factor: 2.751, year: 2004

  3. Phylogenetic relationships in the genus Leonardoxa (Leguminosae: Caesalpinioideae) inferred from chloroplast trnL intron and trnL-trnF intergenic spacer sequences.

    Science.gov (United States)

    Brouat, Carine; Gielly, Ludovic; McKey, Doyle

    2001-01-01

    The African genus LEONARDOXA: (Leguminosae: Caesalpinioideae) comprises two Congolean species and a group of four mostly allopatric subspecies principally located in Cameroon and clustered together in the L. africana complex. LEONARDOXA: provides a good opportunity to investigate the evolutionary history of ant-plant mutualisms, as it exhibits various grades of ant-plant interactions from diffuse to obligate and symbiotic associations. We present in this paper the first molecular phylogenetic study of this genus. We sequenced both the chloroplast DNA trnL intron (677 aligned base pairs [bp]) and trnL-trnF intergene spacer (598 aligned bp). Inferred phylogenetic relationships suggested first that the genus is paraphyletic. The L. africana complex is clearly separated from the two Congolean species, and the integrity of the genus is thus in question. In the L. africana complex, our data showed a lack of congruence between clades suggested by morphological and chloroplast characters. This, and the low level of molecular divergence found between subspecies, suggests gene flow and introgressive events in the L. africana complex.

  4. Phylogeny of Eleusine (Poaceae: Chloridoideae) based on nuclear ITS and plastid trnT-trnF sequences.

    Science.gov (United States)

    Neves, Susana S; Swire-Clark, Ginger; Hilu, Khidir W; Baird, Wm Vance

    2005-05-01

    Phylogenetic relationships in the genus Eleusine (Poaceae: Chloridoideae) were investigated using nuclear ITS and plastid trnT-trnF sequences. Separate and combined data sets were analyzed using parsimony, distance, and likelihood based methods, including Bayesian. Data congruence was examined using character and topological measures. Significant data heterogeneity was detected, but there was little conflict in the topological substructure measures for triplets and quartets, and resolution and clade support increased in the combined analysis. Data incongruence may be a result of noise and insufficient information in the slower evolving trnT-trnF. Monophyly of Eleusine is strongly supported in all analyses, but basal relationships in the genus remain uncertain. There is good support for a CAIK clade (E. coracana subsp. coracana and africana, E. indica, and E. kigeziensis), with E. tristachya as its sister group. Two putative ITS homeologues (A and B loci) were identified in the allotetraploid E. coracana; the 'B' locus sequence type was not found in the remaining species. Eleusine coracana and its putative 'A' genome donor, the diploid E. indica, are confirmed close allies, but sequence data contradicts the hypothesis that E. floccifolia is its second genome donor. The 'B' genome donor remains unidentified and may be extinct.

  5. Phylogenetic relationships in Solanaceae and related species based on cpDNA sequence from plastid trnE-trnT region

    Directory of Open Access Journals (Sweden)

    Danila Montewka Melotto-Passarin

    2008-01-01

    Full Text Available Intergenic spacers of chloroplast DNA (cpDNA are very useful in phylogenetic and population genetic studiesof plant species, to study their potential integration in phylogenetic analysis. The non-coding trnE-trnT intergenic spacer ofcpDNA was analyzed to assess the nucleotide sequence polymorphism of 16 Solanaceae species and to estimate its ability tocontribute to the resolution of phylogenetic studies of this group. Multiple alignments of DNA sequences of trnE-trnT intergenicspacer made the identification of nucleotide variability in this region possible and the phylogeny was estimated by maximumparsimony and rooted with Convolvulaceae Ipomoea batatas, the most closely related family. Besides, this intergenic spacerwas tested for the phylogenetic ability to differentiate taxonomic levels. For this purpose, species from four other families wereanalyzed and compared with Solanaceae species. Results confirmed polymorphism in the trnE-trnT region at different taxonomiclevels.

  6. Taxonomy, phylogenetics and biogeography of Chesneya (Fabaceae), evidenced from data of three sequences, ITS, trnS-trnG, and rbcL

    Science.gov (United States)

    Ming-Li Zhang; Zhi-Bin Wen; Xiao-Li Hao; Vyacheslav V. Byalt; Alexander P. Sukhorukov; Stewart C. Sanderson

    2015-01-01

    Plants of Central Asia have played a significant role in the origin of floras of Eurasia and the Northern Hemisphere. Chesneya, a small leguminous genus occurring in Central Asia, western Asia, and Tibet, is used to establish phylogenetic relationships and discuss the evolutionary and biogeographical history based on sequence data of ITS and trnS-trnG and rbcL.We...

  7. A trnL-F based phylogeny for species of Pelargonium (Geraniaceaea) with small chromosomes

    NARCIS (Netherlands)

    Bakker, F.T.; Culham, A.; Daugherty, L.C.; Gibby, M.

    1999-01-01

    Phylogenetic analysis was performed of 921 positions of trnL (UAA) 5 exon ¿ trnF (GAA) exon chloroplast DNA regions from 68 representatives ofPelargonium sectt.Campylia, Cortusina, Glaucophyllum, Hoarea, Isopetalum, Ligularia, Otidia, Pelargonium, Peristera, Polyactium, andReniformia, together with

  8. Chloroplast DNA analysis of Tunisian cork oak populations (Quercus suber L.): sequence variations and molecular evolution of the trnL (UAA)-trnF (GAA) region.

    Science.gov (United States)

    Abdessamad, A; Baraket, G; Sakka, H; Ammari, Y; Ksontini, M; Hannachi, A Salhi

    2016-10-24

    Sequences of the trnL-trnF spacer and combined trnL-trnF region in chloroplast DNA of cork oak (Quercus suber L.) were analyzed to detect polymorphisms and to elucidate molecular evolution and demographic history. The aligned sequences varied in length and nucleotide composition. The overall ratio of transition/transversion (ti/tv) of 0.724 for the intergenic spacer and 0.258 for the pooled sequences were estimated, and indicated that transversions are more frequent than transitions. The molecular evolution and demographic history of Q. suber were investigated. Neutrality tests (Tajima's D and Fu and Li) ruled out the null hypothesis of a strictly neutral model, and Fu's Fs and Ramos-Onsins and Rozas' R2 confirmed the recent expansion of cork oak trees, validating its persistency in North Africa since the last glaciation during the Quaternary. The observed uni-modal mismatch distribution and the Harpending's raggedness index confirmed the demographic history model for cork oak. A phylogenetic dendrogram showed that the distribution of Q. suber trees occurs independently of geographical origin, the relief of the population site, and the bioclimatic stages. The molecular history and cytoplasmic diversity suggest that in situ and ex situ conservation strategies can be recommended for preserving landscape value and facing predictable future climatic changes.

  9. Trækonstruktioner

    DEFF Research Database (Denmark)

    Larsen, H.J.; Riberholt, H.

    Denne anvisning behandler materialer til trækonstruktioner og beregning af sædvanlige elementer og konstruktioner i henhold til Trænormen fra 2003 med tillæg. Forbindelser behandles i SBI-anvisning 194: Trækonstruktioner. Forbindelser. Anvisningen er tænkt anvendt af projekterende og som lærebog på...

  10. Phylogenetic relationships in Taxodiaceae and Cupressaceae sensu stricto based on matK gene, chlL gene, trnL-trnF IGS region, and trnL intron sequences.

    Science.gov (United States)

    Kusumi, J; Tsumura, Y; Yoshimaru, H; Tachida, H

    2000-10-01

    Nucleotide sequences from four chloroplast genes, the matK, chlL, intergenic spacer (IGS) region between trnL and trnF, and an intron of trnL, were determined from all species of Taxodiaceae and five species of Cupressaceae sensu stricto (s.s.). Phylogenetic trees were constructed using the maximum parsimony and the neighbor-joining methods with Cunninghamia as an outgroup. These analyses provided greater resolution of relationships among genera and higher bootstrap supports for clades compared to previous analyses. Results indicate that Taiwania diverged first, and then Athrotaxis diverged from the remaining genera. Metasequoia, Sequoia, and Sequoiadendron form a clade. Taxodium and Glyptostrobus form a clade, which is the sister to Cryptomeria. Cupressaceae s.s. are derived from within Taxodiaceae, being the most closely related to the Cryptomeria/Taxodium/Glyptostrobus clade. These relationships are consistent with previous morphological groupings and the analyses of molecular data. In addition, we found acceleration of evolutionary rates in Cupressaceae s.s. Possible causes for the acceleration are discussed.

  11. Use of the psbA-trnH region to authenticate medicinal species of Fabaceae.

    Science.gov (United States)

    Gao, Ting; Ma, Xinye; Zhu, Xunzhi

    2013-01-01

    Fabaceae is a huge family that contains a large number of medicinal plants, many of which are commonly used in Chinese traditional medicine. However, traditional taxonomy has not been able to meet the complicated demands of species discrimination within Fabaceae. Thus, we employed a famous DNA barcode, the psbA-trnH region, to discriminate commonly used medicinal species of the family Fabaceae. Here, the psbA-trnH regions derived from 152 samples were amplified. These samples represented 104 Fabaceae medicinal species from 60 genera, including 25 authentic Fabaceae species listed in the Chinese pharmacopoeia and common adulterant species. The results indicate that the psbA-trnH region performed well in terms of its universality and high variability in length and composition. Species discriminative power analysis of the psbA-trnH region showed that 91.3% of species could be identified successfully by the BLAST1 method in conjunction with the nearest distance method. And, the species resolution rate of the TaxonGap method exceeded 93%. The results provide support for the use of the psbA-trnH plastid region as a sensitive marker to the authentication of Fabaceae medicinal plants.

  12. TrnH-psbA sequence analyses of asparagus cochinchinensis from different geographical origin in China

    Directory of Open Access Journals (Sweden)

    Ma Yingzi

    2017-01-01

    Full Text Available This template explains and demonstrates how to prepare your camera-ready paper for The trnH-psbA sequences of 13 Asparagus cochinchinensis populations from 6 provinces of China were studied. The results showed that length of trnH-psbA change and the mutation of GC content were small. The length of trnH-psbA sequences were from 619 bp to 632 bp, and the GC content was about 36%. The total variation rates of 13 populations were from 2.21% to 3.47%, when the missing sites were considered as variation sites. A. cochinchinensis from different sources had 10 information sites in trnH-psbA sequence, accounting for 1.58% of the total sequence. The information sites were located in the sites 8, 9, 120, 457, 458, 486, 487, 491, 492, and 593, respectively. Clustering analysis showed that the Qianxi and Hengshan populations clustered together; Dushan, Yuqing, and Guangzhou populations were grouped; Nanning and Xinning populations formed another cluster. trnH-psbA sequences could identify different A. cochinchinensis populations. Clustering of different A. cochinchinensis populations related primarily to latitude and had little relationship with longitude.

  13. Study on inter-taxon population structure and diversity variation of hosta inferring from trnG-trnS regional cpDNA

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    Hasan Mehraj

    2017-12-01

    Full Text Available Diversity studies are now a key tool in genetic conservation work. The perennial herb genus Hosta showed a complex radiation of numerous species in mountains and riversides around the Shikoku Island, Japan. The purpose of this study was to evaluate trnS-trnG regional genetic structure and the genetic divergence within hosta taxa populations in this area. We sequenced trnS-trnG regional (chloroplast DNA cpDNA in 81 populations comprising 399 individuals of 11 Hosta taxa collected from Shikoku area. The different numbers of haplotypes were found in different taxon. The divergences of population of Hosta genus and individual taxon were shown in NJ phylogenetic tree. The highest number of haplotypes (14 was found in H. longipes var. gracillima. H. sieboldiana and H. kiyosumiensis populations showed the maximum haplotype diversity (1.0, and H. alismifolia showed maximum nucleotide diversity (π: 0.012. The genetic structures of the H. tardiva with H. kikutii var. caput-avis (FST divergence: 52.7% and H. sieboldiana with H. tardiva (FST divergence: 52.2% populations were greatly differentiated from each other (FST value: >0.15 to 0.25. We found maximum evolutionary divergence (0.009 between H. alismifolia and H. kikutii var. polyneuron populations. The significant negative neutrality test values are the evidence of expansion of the total population. H. sieboldiana and H. kiyosumiensis are more widely distributed than other taxa. H. sieboldiana, H. alismifolia, H. longipes var. gracillima and H. kikutii var. polyneuron showed the excessive low frequency variants.

  14. Supernetwork identifies multiple events of plastid trnF(GAA) pseudogene evolution in the Brassicaceae

    Czech Academy of Sciences Publication Activity Database

    Koch, M.A.; Dobeš, Ch.; Kiefer, Ch.; Schmickl, R.; Klimeš, Leoš; Lysak, M.A.

    2007-01-01

    Roč. 24, č. 1 (2007), s. 63-73 ISSN 0737-4038 R&D Projects: GA AV ČR(CZ) KJB601630606; GA ČR GA206/03/1219 Institutional research plan: CEZ:AV0Z60050516 Keywords : Cruciferae evolution * trnF gene * supernetwork Subject RIV: EF - Botanics Impact factor: 6.438, year: 2007

  15. Phylogenetic inferences of Nepenthes species in Peninsular Malaysia revealed by chloroplast (trnL intron) and nuclear (ITS) DNA sequences

    OpenAIRE

    Bunawan, Hamidun; Yen, Choong Chee; Yaakop, Salmah; Noor, Normah Mohd

    2017-01-01

    Background The chloroplastic trnL intron and the nuclear internal transcribed spacer (ITS) region were sequenced for 11 Nepenthes species recorded in Peninsular Malaysia to examine their phylogenetic relationship and to evaluate the usage of trnL intron and ITS sequences for phylogenetic reconstruction of this genus. Results Phylogeny reconstruction was carried out using neighbor-joining, maximum parsimony and Bayesian analyses. All the trees revealed two major clusters, a lowland group consi...

  16. The architecture of the chloroplast trnH-psbA non-coding region in angiosperms

    Czech Academy of Sciences Publication Activity Database

    Štorchová, Helena; Olson, M.S.

    2007-01-01

    Roč. 268, 1-4 (2007), s. 235-256 ISSN 0378-2697 R&D Projects: GA MŠk(CZ) LC06004 Grant - others:ESPSCor Visiting Scholar Research Grant(US) NSF DEB 0317115 Institutional research plan: CEZ:AV0Z50380511 Source of funding: V - iné verejné zdroje ; V - iné verejné zdroje Keywords : Chloroplast DNA * psbA-trnH intergenic region * Silene * deletions * insertions and inversions in stem-loop region * psbA 3´untranslated region * RNA secondary structure Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 1.492, year: 2007

  17. Identification of Dendrobium species by a candidate DNA barcode sequence: the chloroplast psbA-trnH intergenic region.

    Science.gov (United States)

    Yao, Hui; Song, Jing-Yuan; Ma, Xin-Ye; Liu, Chang; Li, Ying; Xu, Hong-Xi; Han, Jian-Ping; Duan, Li-Sheng; Chen, Shi-Lin

    2009-05-01

    DNA barcoding is a novel technology that uses a standard DNA sequence to facilitate species identification. Although a consensus has not been reached regarding which DNA sequences can be used as the best plant barcodes, the psbA-trnH spacer region has been tested extensively in recent years. In this study, we hypothesize that the psbA-trnH spacer regions are also effective barcodes for Dendrobium species. We have sequenced the chloroplast psbA-trnH intergenic spacers of 17 Dendrobium species to test this hypothesis. The sequences were found to be significantly different from those of other species, with percentages of variation ranging from 0.3 % to 2.3 % and an average of 1.2 %. In contrast, the intraspecific variation among the Dendrobium species studied ranged from 0 % to 0.1 %. The sequence difference between the psbA-trnH sequences of 17 Dendrobium species and one Bulbophyllum odoratissimum ranged from 2.0 % to 3.1 %, with an average of 2.5 %. Our results support the notion that the psbA-trnH intergenic spacer region could be used as a barcode to distinguish various Dendrobium species and to differentiate Dendrobium species from other adulterating species. Copyright Georg Thieme Verlag KG Stuttgart. New York.

  18. Unique haplotypes of cacao trees as revealed by trnH-psbA chloroplast DNA

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    Nidia Gutiérrez-López

    2016-04-01

    Full Text Available Cacao trees have been cultivated in Mesoamerica for at least 4,000 years. In this study, we analyzed sequence variation in the chloroplast DNA trnH-psbA intergenic spacer from 28 cacao trees from different farms in the Soconusco region in southern Mexico. Genetic relationships were established by two analysis approaches based on geographic origin (five populations and genetic origin (based on a previous study. We identified six polymorphic sites, including five insertion/deletion (indels types and one transversion. The overall nucleotide diversity was low for both approaches (geographic = 0.0032 and genetic = 0.0038. Conversely, we obtained moderate to high haplotype diversity (0.66 and 0.80 with 10 and 12 haplotypes, respectively. The common haplotype (H1 for both networks included cacao trees from all geographic locations (geographic approach and four genetic groups (genetic approach. This common haplotype (ancient derived a set of intermediate haplotypes and singletons interconnected by one or two mutational steps, which suggested directional selection and event purification from the expansion of narrow populations. Cacao trees from Soconusco region were grouped into one cluster without any evidence of subclustering based on AMOVA (FST = 0 and SAMOVA (FST = 0.04393 results. One population (Mazatán showed a high haplotype frequency; thus, this population could be considered an important reservoir of genetic material. The indels located in the trnH-psbA intergenic spacer of cacao trees could be useful as markers for the development of DNA barcoding.

  19. Phylogenetic inferences of Nepenthes species in Peninsular Malaysia revealed by chloroplast (trnL intron) and nuclear (ITS) DNA sequences.

    Science.gov (United States)

    Bunawan, Hamidun; Yen, Choong Chee; Yaakop, Salmah; Noor, Normah Mohd

    2017-01-26

    The chloroplastic trnL intron and the nuclear internal transcribed spacer (ITS) region were sequenced for 11 Nepenthes species recorded in Peninsular Malaysia to examine their phylogenetic relationship and to evaluate the usage of trnL intron and ITS sequences for phylogenetic reconstruction of this genus. Phylogeny reconstruction was carried out using neighbor-joining, maximum parsimony and Bayesian analyses. All the trees revealed two major clusters, a lowland group consisting of N. ampullaria, N. mirabilis, N. gracilis and N. rafflesiana, and another containing both intermediately distributed species (N. albomarginata and N. benstonei) and four highland species (N. sanguinea, N. macfarlanei, N. ramispina and N. alba). The trnL intron and ITS sequences proved to provide phylogenetic informative characters for deriving a phylogeny of Nepenthes species in Peninsular Malaysia. To our knowledge, this is the first molecular phylogenetic study of Nepenthes species occurring along an altitudinal gradient in Peninsular Malaysia.

  20. Ancient paralogy in the cpDNA trnL-F region in Annonaceae: implications for plant molecular systematics

    NARCIS (Netherlands)

    Pirie, M.D.; Vargas, M.P.B.; Botermans, M.; Bakker, F.T.; Chatrou, L.W.

    2007-01-01

    The plastid trnL-F region has proved useful in molecular phylogenetic studies addressing diverse evolutionary questions from biogeographic history to character evolution in a broad range of plant groups. An important assumption for phylogenetic reconstruction is that data used in combined analyses

  1. Species identification of medicinal pteridophytes by a DNA barcode marker, the chloroplast psbA-trnH intergenic region.

    Science.gov (United States)

    Ma, Xin-Ye; Xie, Cai-Xiang; Liu, Chang; Song, Jing-Yuan; Yao, Hui; Luo, Kun; Zhu, Ying-Jie; Gao, Ting; Pang, Xiao-Hui; Qian, Jun; Chen, Shi-Lin

    2010-01-01

    Medicinal pteridophytes are an important group used in traditional Chinese medicine; however, there is no simple and universal way to differentiate various species of this group by morphological traits. A novel technology termed "DNA barcoding" could discriminate species by a standard DNA sequence with universal primers and sufficient variation. To determine whether DNA barcoding would be effective for differentiating pteridophyte species, we first analyzed five DNA sequence markers (psbA-trnH intergenic region, rbcL, rpoB, rpoC1, and matK) using six chloroplast genomic sequences from GeneBank and found psbA-trnH intergenic region the best candidate for availability of universal primers. Next, we amplified the psbA-trnH region from 79 samples of medicinal pteridophyte plants. These samples represented 51 species from 24 families, including all the authentic pteridophyte species listed in the Chinese pharmacopoeia (2005 version) and some commonly used adulterants. We found that the sequence of the psbA-trnH intergenic region can be determined with both high polymerase chain reaction (PCR) amplification efficiency (94.1%) and high direct sequencing success rate (81.3%). Combined with GeneBank data (54 species cross 12 pteridophyte families), species discriminative power analysis showed that 90.2% of species could be separated/identified successfully by the TaxonGap method in conjunction with the Basic Local Alignment Search Tool 1 (BLAST1) method. The TaxonGap method results further showed that, for 37 out of 39 separable species with at least two samples each, between-species variation was higher than the relevant within-species variation. Thus, the psbA-trnH intergenic region is a suitable DNA marker for species identification in medicinal pteridophytes.

  2. Incorporating trnH-psbA to the core DNA barcodes improves significantly species discrimination within southern African Combretaceae

    Directory of Open Access Journals (Sweden)

    Jephris Gere

    2013-12-01

    Full Text Available Recent studies indicate that the discriminatory power of the core DNA barcodes (rbcLa + matK for land plants may have been overestimated since their performance have been tested only on few closely related species. In this study we focused mainly on how the addition of complementary barcodes (nrITS and trnH-psbA to the core barcodes will affect the performance of the core barcodes in discriminating closely related species from family to section levels. In general, we found that the core barcodes performed poorly compared to the various combinations tested. Using multiple criteria, we finally advocated for the use of the core + trnH-psbA as potential DNA barcode for the family Combretaceae at least in southern Africa. Our results also indicate that the success of DNA barcoding in discriminating closely related species may be related to evolutionary and possibly the biogeographic histories of the taxonomic group tested.

  3. [Reconstruction of the phylogenetic position of larch (Larix sukaczewii Dylis) by sequencing data for the trnK intron of chloroplast DNA].

    Science.gov (United States)

    Bashalkhanov, S I; Konstantinov, Iu M; Verbitskiĭ, D S; Kobzev, V F

    2003-10-01

    To reconstruct the systematic relationships of larch Larix sukaczewii, we used the chloroplast trnK intron sequences of L. decidua, L. sukaczewii, L. sibirica, L. czekanovskii, and L. gmelinii. Analysis of phylogenetic trees constructed using the maximum parsimony and maximum likelihood methods showed a clear divergence of the trnK intron sequences between L. sukaczewii and L. sibirica. This divergence reaches intraspecific level, which supports a previously published hypothesis on the taxonomic isolation of L. sukaczewii.

  4. Safety features of TR-2 reactor

    International Nuclear Information System (INIS)

    Tuerker, T.

    2001-01-01

    TR-2 is a swimming pool type research reactor with 5 MW thermal power and uses standard MTR plate type fuel elements. Each standard fuel element consist of 23 fuel plates with a meat + cladding thickness of 0.127 cm, coolant channel clearance is 0.21 cm. Originally TR-2 is designed for %93 enriched U-Al. Alloy fuel meat.This work is based on the preparation of the Final Safety Analyses Report (FSAR) of the TR-2 reactor. The main aspect is to investigate the behaviour of TR-2 reactor under the accident and abnormal operating conditions, which cowers the accident spectrum unique for the TR-2 reactor. This presentation covers some selected transient analyses which are important for the safety aspects of the TR-2 reactor like reactivity induced startup accidents, pump coast down (Loss of Flow Accident, LOFA) and other accidents which are charecteristic to the TR-2

  5. Friluftsinstallationer i træer

    DEFF Research Database (Denmark)

    Skov, Simon; Thomsen, Iben Margrete

    2015-01-01

    Abebaner, treetop walking, high rope adventure, slackline, træhuse og parkour-baner er alle installationer, som bruger træerne som støtte, enten midlertidigt eller permanent. Den nye sport, turistattraktionen eller team building-redskabet sætter i alle tilfælde træerne på prøve. Der følger positiv...

  6. Reconstruction of structural evolution in the trnL intron P6b loop of symbiotic Nostoc (Cyanobacteria).

    Science.gov (United States)

    Olsson, Sanna; Kaasalainen, Ulla; Rikkinen, Jouko

    2012-02-01

    In this study we reconstruct the structural evolution of the hyper-variable P6b region of the group I trnLeu intron in a monophyletic group of lichen-symbiotic Nostoc strains and establish it as a useful marker in the phylogenetic analysis of these organisms. The studied cyanobacteria occur as photosynthetic and/or nitrogen-fixing symbionts in lichen species of the diverse Nephroma guild. Phylogenetic analyses and secondary structure reconstructions are used to improve the understanding of the replication mechanisms in the P6b stem-loop and to explain the observed distribution patterns of indels. The variants of the P6b region in the Nostoc clade studied consist of different combinations of five sequence modules. The distribution of indels together with the ancestral character reconstruction performed enables the interpretation of the evolution of each sequence module. Our results indicate that the indel events are usually associated with single nucleotide changes in the P6b region and have occurred several times independently. In spite of their homoplasy, they provide phylogenetic information for closely related taxa. Thus we recognize that features of the P6b region can be used as molecular markers for species identification and phylogenetic studies involving symbiotic Nostoc cyanobacteria.

  7. Taxonomic Identification of Mediterranean Pines and Their Hybrids Based on the High Resolution Melting (HRM) and trnL Approaches: From Cytoplasmic Inheritance to Timber Tracing

    Science.gov (United States)

    Ganopoulos, Ioannis; Aravanopoulos, Filippos; Madesis, Panagiotis; Pasentsis, Konstantinos; Bosmali, Irene; Ouzounis, Christos; Tsaftaris, Athanasios

    2013-01-01

    Fast and accurate detection of plant species and their hybrids using molecular tools will facilitate the assessment and monitoring of local biodiversity in an era of climate and environmental change. Herein, we evaluate the utility of the plastid trnL marker for species identification applied to Mediterranean pines (Pinus spp.). Our results indicate that trnL is a very sensitive marker for delimiting species biodiversity. Furthermore, High Resolution Melting (HRM) analysis was exploited as a molecular fingerprint for fast and accurate discrimination of Pinus spp. DNA sequence variants. The trnL approach and the HRM analyses were extended to wood samples of two species (Pinus nigra and Pinus sylvestris) with excellent results, congruent to those obtained using leaf tissue. Both analyses demonstrate that hybrids from the P. brutia (maternal parent) × P. halepensis (paternal parent) cross, exhibit the P. halepensis profile, confirming paternal plastid inheritance in Group Halepensis pines. Our study indicates that a single one-step reaction method and DNA marker are sufficient for the identification of Mediterranean pines, their hybrids and the origin of pine wood. Furthermore, our results underline the potential for certain DNA regions to be used as novel biological information markers combined with existing morphological characters and suggest a relatively reliable and open taxonomic system that can link DNA variation to phenotype-based species or hybrid assignment status and direct taxa identification from recalcitrant tissues such as wood samples. PMID:23577179

  8. The internal transcribed spacer (ITS region and trnH-psbA [corrected] are suitable candidate loci for DNA barcoding of tropical tree species of India.

    Directory of Open Access Journals (Sweden)

    Abhinandan Mani Tripathi

    Full Text Available DNA barcoding as a tool for species identification has been successful in animals and other organisms, including certain groups of plants. The exploration of this new tool for species identification, particularly in tree species, is very scanty from biodiversity-rich countries like India. rbcL and matK are standard barcode loci while ITS, and trnH-psbA are considered as supplementary loci for plants.Plant barcode loci, namely, rbcL, matK, ITS, trnH-psbA, and the recently proposed ITS2, were tested for their efficacy as barcode loci using 300 accessions of tropical tree species. We tested these loci for PCR, sequencing success, and species discrimination ability using three methods. rbcL was the best locus as far as PCR and sequencing success rate were concerned, but not for the species discrimination ability of tropical tree species. ITS and trnH-psbA were the second best loci in PCR and sequencing success, respectively. The species discrimination ability of ITS ranged from 24.4 percent to 74.3 percent and that of trnH-psbA was 25.6 percent to 67.7 percent, depending upon the data set and the method used. matK provided the least PCR success, followed by ITS2 (59. 0%. Species resolution by ITS2 and rbcL ranged from 9.0 percent to 48.7 percent and 13.2 percent to 43.6 percent, respectively. Further, we observed that the NCBI nucleotide database is poorly represented by the sequences of barcode loci studied here for tree species.Although a conservative approach of a success rate of 60-70 percent by both ITS and trnH-psbA may not be considered as highly successful but would certainly help in large-scale biodiversity inventorization, particularly for tropical tree species, considering the standard success rate of plant DNA barcode program reported so far. The recommended matK and rbcL primers combination may not work in tropical tree species as barcode markers.

  9. Landbrugets trædemølle

    DEFF Research Database (Denmark)

    Hansen, Henning Otte

    2016-01-01

    Teorien om landbrugets trædemølle siger, at teknologi medfører stigende produktivitet, stigende udbud og dermed faldende priser. Dermed øges behovet for ny teknologi. Det vedvarende teknologipres gavner de innovative landmænd, mens de mere afventende landmænd kun oplever de negative virkninger i...... form af prisfald. I denne artikel beskrives nærmere de enkelte elementer i trædemøllen. Samtidig vurderes trædemøllens betydning og mulige påvirkning. Det konkluderes, at trædemøllen, dens forudsætninger og afledte virkninger stadig er fuldt gældende. Det er ikke muligt for et enkelt land eller region...... af bremse trædemøllen på lang sigt. På lokalt plan kan man løse nogle sociale og økonomiske problemer skabt af trædemøllen gennem nemmere afvandring....

  10. ITS and trnH-psbA as Efficient DNA Barcodes to Identify Threatened Commercial Woody Angiosperms from Southern Brazilian Atlantic Rainforests.

    Science.gov (United States)

    Bolson, Mônica; Smidt, Eric de Camargo; Brotto, Marcelo Leandro; Silva-Pereira, Viviane

    2015-01-01

    The Araucaria Forests in southern Brazil are part of the Atlantic Rainforest, a key hotspot for global biodiversity. This habitat has experienced extensive losses of vegetation cover due to commercial logging and the intense use of wood resources for construction and furniture manufacturing. The absence of precise taxonomic tools for identifying Araucaria Forest tree species motivated us to test the ability of DNA barcoding to distinguish species exploited for wood resources and its suitability for use as an alternative testing technique for the inspection of illegal timber shipments. We tested three cpDNA regions (matK, trnH-psbA, and rbcL) and nrITS according to criteria determined by The Consortium for the Barcode of Life (CBOL). The efficiency of each marker and selected marker combinations were evaluated for 30 commercially valuable woody species in multiple populations, with a special focus on Lauraceae species. Inter- and intraspecific distances, species discrimination rates, and ability to recover species-specific clusters were evaluated. Among the regions and different combinations, ITS was the most efficient for identifying species based on the 'best close match' test; similarly, the trnH-psbA + ITS combination also demonstrated satisfactory results. When combining trnH-psbA + ITS, Maximum Likelihood analysis demonstrated a more resolved topology for internal branches, with 91% of species-specific clusters. DNA barcoding was found to be a practical and rapid method for identifying major threatened woody angiosperms from Araucaria Forests such as Lauraceae species, presenting a high confidence for recognizing members of Ocotea. These molecular tools can assist in screening those botanical families that are most targeted by the timber industry in southern Brazil and detecting certain species protected by Brazilian legislation and could be a useful tool for monitoring wood exploitation.

  11. A two-locus global DNA barcode for land plants: the coding rbcL gene complements the non-coding trnH-psbA spacer region.

    Science.gov (United States)

    Kress, W John; Erickson, David L

    2007-06-06

    A useful DNA barcode requires sufficient sequence variation to distinguish between species and ease of application across a broad range of taxa. Discovery of a DNA barcode for land plants has been limited by intrinsically lower rates of sequence evolution in plant genomes than that observed in animals. This low rate has complicated the trade-off in finding a locus that is universal and readily sequenced and has sufficiently high sequence divergence at the species-level. Here, a global plant DNA barcode system is evaluated by comparing universal application and degree of sequence divergence for nine putative barcode loci, including coding and non-coding regions, singly and in pairs across a phylogenetically diverse set of 48 genera (two species per genus). No single locus could discriminate among species in a pair in more than 79% of genera, whereas discrimination increased to nearly 88% when the non-coding trnH-psbA spacer was paired with one of three coding loci, including rbcL. In silico trials were conducted in which DNA sequences from GenBank were used to further evaluate the discriminatory power of a subset of these loci. These trials supported the earlier observation that trnH-psbA coupled with rbcL can correctly identify and discriminate among related species. A combination of the non-coding trnH-psbA spacer region and a portion of the coding rbcL gene is recommended as a two-locus global land plant barcode that provides the necessary universality and species discrimination.

  12. ITS and trnH-psbA as Efficient DNA Barcodes to Identify Threatened Commercial Woody Angiosperms from Southern Brazilian Atlantic Rainforests.

    Directory of Open Access Journals (Sweden)

    Mônica Bolson

    Full Text Available The Araucaria Forests in southern Brazil are part of the Atlantic Rainforest, a key hotspot for global biodiversity. This habitat has experienced extensive losses of vegetation cover due to commercial logging and the intense use of wood resources for construction and furniture manufacturing. The absence of precise taxonomic tools for identifying Araucaria Forest tree species motivated us to test the ability of DNA barcoding to distinguish species exploited for wood resources and its suitability for use as an alternative testing technique for the inspection of illegal timber shipments. We tested three cpDNA regions (matK, trnH-psbA, and rbcL and nrITS according to criteria determined by The Consortium for the Barcode of Life (CBOL. The efficiency of each marker and selected marker combinations were evaluated for 30 commercially valuable woody species in multiple populations, with a special focus on Lauraceae species. Inter- and intraspecific distances, species discrimination rates, and ability to recover species-specific clusters were evaluated. Among the regions and different combinations, ITS was the most efficient for identifying species based on the 'best close match' test; similarly, the trnH-psbA + ITS combination also demonstrated satisfactory results. When combining trnH-psbA + ITS, Maximum Likelihood analysis demonstrated a more resolved topology for internal branches, with 91% of species-specific clusters. DNA barcoding was found to be a practical and rapid method for identifying major threatened woody angiosperms from Araucaria Forests such as Lauraceae species, presenting a high confidence for recognizing members of Ocotea. These molecular tools can assist in screening those botanical families that are most targeted by the timber industry in southern Brazil and detecting certain species protected by Brazilian legislation and could be a useful tool for monitoring wood exploitation.

  13. Naturlig ventilation og træk

    DEFF Research Database (Denmark)

    Nielsen, Peter Vilhelm

    2002-01-01

    Nye ventilationsprincipper som naturlig ventilation er med til at sætte fokus på de strømningselementer, der skal anvendes til dimensionering af luftfordelingen i et rum. Artiklen anviser, hvordan træk fra vinduer og tagåbninger i rum med naturlig ventilation kan beregnes ved hjælp af...

  14. Blog.tr.ee ei anna alla / Raigo Neudorf

    Index Scriptorium Estoniae

    Neudorf, Raigo

    2007-01-01

    Veebikeskkonna blog.tr.ee arengust ja majandamisest räägivad keskkonna looja Andris Reinmann ja firma OÜ Tr.ee osaniku Mobi Solutions'i esindaja Rain Rannu. Vt. samas: Mis on blog.tr.ee; Kaljundi: blog.tr.ee on hobiprojekt. Kommenteerib nagi.ee juhataja Jüri Kaljundi. Lisatud joonis: Blog.tr.ee unikaalsete külastajate arv nädalas

  15. Assessment of the food habits of the Moroccan dorcas gazelle in M'Sabih Talaa, west central Morocco, using the trnL approach.

    Directory of Open Access Journals (Sweden)

    Moulay Abdeljalil Ait Baamrane

    Full Text Available Food habits of the Moroccan dorcas gazelle, Gazella dorcas massaesyla, previously investigated in the 1980s using microhistological fecal analysis, in the M'Sabih Talaa Reserve, west central Morocco, were re-evaluated over three seasons (spring, summer and autumn 2009 using the trnL approach to determine the diet composition and its seasonal variation from fecal samples. Taxonomic identification was carried out using the identification originating from the database built from EMBL and the list of plant species within the reserve. The total taxonomic richness in the reserve was 130 instead of 171 species in the 1980s. The diet composition revealed to be much more diversified (71 plant taxa belonging to 57 genus and 29 families than it was 22 years ago (29 identified taxa. Thirty-four taxa were newly identified in the diet while 13 reported in 1986-87 were not found. Moroccan dorcas gazelle showed a high preference to Acacia gummifera, Anagallis arvensis, Glebionis coronaria, Cladanthus arabicus, Diplotaxis tenuisiliqua, Erodium salzmannii, Limonium thouini, Lotus arenarius and Zizyphus lotus. Seasonal variations occurred in both number (40-41 taxa in spring-summer and 49 taxa in autumn vs. respectively 23-22 and 26 in 1986-1987 and taxonomic type of eaten plant taxa. This dietary diversification could be attributed either to the difference in methods of analysis, trnL approach having a higher taxonomic resolution, or a potential change in nutritional quality of plants over time.

  16. The use of the hypervariable P8 region of trnL(UAA intron for identification of orchid species: Evidence from restriction site polymorphism analysis.

    Directory of Open Access Journals (Sweden)

    Rajkumar Kishor

    Full Text Available The P8 stem-loop region of the trnL intron, which is known to be hypervariable in size with multiple repeat motifs and created difficulties in alignment, is always excluded in phylogenetic as well as barcode analyses. This region was investigated for species discrimination in 98 taxa of orchids belonging to the tribe Vandeae using in silico mapping of restriction site polymorphism. The length of the P8 regions varied from 200 nucleotides in Aerides rosea to 669 nucleotides in Dendrophylax sallei. Forty two taxa had unique lengths, while as many as eight shared a common length of 521 nucleotides. Of the 35 restriction endonucleases producing digestions in the P8 regions, three, viz., AgsI, ApoI and TspDTI turned out to have recognition sites across all the 98 taxa being studied. When their restriction data were combined, 92 taxa could be discriminated leaving three taxon pairs. However, Acampe papillosa and Aeranthes arachnites despite having similar restriction sites differed in their P8 lengths. This is the first report on thorough investigation of the P8 region of trnL intron for search of species specific restriction sites and hence its use as a potential plant DNA barcode.

  17. Bombyx mori nucleopolyhedrovirus nucleic acid binding proteins BRO-B and BRO-E associate with host T-cell intracellular antigen 1 homologue BmTRN-1 to influence protein synthesis during infection.

    Science.gov (United States)

    Kotani, Eiji; Muto, Sayaka; Ijiri, Hiroshi; Mori, Hajime

    2015-07-01

    Previous reports have indicated that the Bombyx mori nucleopolyhedrovirus (BmNPV) nucleic acid binding proteins BRO-B and BRO-E are expressed during the early stage of infection and that the BRO family likely supports the regulation of mRNA; however, no study has directly examined the function of BRO family proteins in virus-permissive cells. Here, we show that BRO-B and BRO-E associate with cellular T-cell intracellular antigen 1 homologue (BmTRN-1), a translational regulator, and other cellular translation-related proteins in silkworm cells during viral infection. We created BM-N cells that expressed BRO-B/E to study molecular interactions between BmTRN-1 and BRO-B/E and how they influenced protein synthesis. Fluorescent microscopy revealed that BmTRN-1 was localized in cytoplasmic foci during BmNPV infection. Immunofluorescence studies confirmed that BmTRN-1 and BRO-B/E were colocalized in the amorphous conspicuous cytoplasmic foci. Reporter gene studies revealed that co-expression of BRO-B/E synergistically led to a significant decrease in protein synthesis from a designed transcript carrying the 5'untranslated region of a cellular mRNA with no significant change of transcript abundance. Additionally, RNA interference-mediated knockdown of BmTRN-1 resulted in a marked inhibition of the ability of BRO-B/E to regulate the transcript. These results suggested that the association of BmTRN-1 with BRO-B/E is responsible for the inhibitory regulation of certain mRNAs at the post-transcriptional level and add an additional mechanism for how baculoviruses control protein synthesis during infection.

  18. Neuroblastomicose: registro de três casos

    Directory of Open Access Journals (Sweden)

    Ehrenfried O. Wittig

    1968-03-01

    Full Text Available São relatados três casos de neuroblastomicose de sintomatologia variada (urna forma tumoral cerebelar, urna forma abscedante troncular e cerebral e urna forma granulomatosa difusa. No caso da forma tumoral cerebelar havia associação com cisticercose cerebral. Alterações medulares não foram evidenciadas no único caso em que foi possível examinar êste setor do sistema nervoso central (caso 2.

  19. 3rd MeTrApp Conference

    CERN Document Server

    Lovasz, Erwin-Christian; Hüsing, Mathias

    2015-01-01

    This volume deals with topics such as mechanism and machine design, biomechanics and medical engineering, gears, mechanical transmissions, mechatronics, computational and experimental methods, dynamics of mechanisms and machines, micromechanisms and microactuators, and history of mechanisms and transmissions. Following MeTrApp 2011 and 2013, held under the auspices of the IFToMM, these proceedings of the 3rd Conference on Mechanisms, Transmissions and Applications offer a platform for original research presentations for researchers, scientists, industry experts and students in the fields of mechanisms and transmissions with special emphasis on industrial applications in order to stimulate the exchange of new and innovative ideas.

  20. Trükitööstuste TOP 50

    Index Scriptorium Estoniae

    2002-01-01

    Trükitööstuste TOP 50. Käibe TOP 30. Käibe kasum TOP 30. Kasvu TOP 30. Kasumi kasvu TOP 30. Rentaabluse TOP. Varade tootlikkuse TOP. Trükitööstusettevõtete üldandmed. Trükitööstusettevõtete finantsandmed

  1. The interstellar extinction in the open clusters Tr 14, Tr 15, Tr 16/Cr 232 and Cr 228 in NGC 3372. New near-infrared photometry

    International Nuclear Information System (INIS)

    Tapia, M.; Roth, M.; Ruiz, M.T.

    1988-01-01

    Near-infrared JHKL photometry of more than 200 stars, members of the open clusters Tr14, Tr15, Tr16, Cr228 and Cr232 in the Carina Nebula are presented. From comparing these results with the available visual photometry and spectroscopy, it is found that, except in Tr15, the intracluster reddening is characterized by a 'normal' extinction law at λ > 0.5μm but is highly anomalous and variable in the U- and B-bands. This behaviour may be explained by the presence of intracluster interstellar grains 'processed' by shock waves presumably associated with the explosive history of η Carinae. All clusters are found to be at the same distance from the Sun at d = 2.4 ± 0.2 kpc or Vsub(o) - Msub(v) 11.9 ± 0.2. The total amount of reddening, though, differs significantly from cluster to cluster. (author)

  2. Aasta trükise 2000 võitjad selgunud

    Index Scriptorium Estoniae

    2000-01-01

    Rahvusvaheline žürii valis välja 6 raamatut, reklaam- ja väiketrükist ning etiketiseeria. Parimad trükised, trükikojad, kujundajad. Publikuauhinna võitsid üliõpilased Terje Homutov, Monika Eensalu, Tim Kolk

  3. Kronisk træthedssyndrom, en usynlig sygdom?

    DEFF Research Database (Denmark)

    Jentoft Olsen, Rikke Katrine; Martlev, Lasse; Fernandez Guerra, Paula

    2018-01-01

    Seahorse XF-teknologi kan måle cellers evne til at producere energi under stress og afslører dysfunktionelle energisystemer i kronisk træthedssyndrom......Seahorse XF-teknologi kan måle cellers evne til at producere energi under stress og afslører dysfunktionelle energisystemer i kronisk træthedssyndrom...

  4. The Evolution of NR TrA (Nova TrA 2008) from 2008 through 2017

    Science.gov (United States)

    Walter, Frederick M.; Burwitz, Vadim; Kafka, Stella

    2018-06-01

    The classical nova NR TrA was discovered as an O-type optically-thick classical nova. There is no evidence that it formed dust. Within four years the envelope became sufficiently thin to reveal an eclipsing accretion disk-dominated system with orbitally-modulated permitted lines of C IV, N V, and O VI. XMM observations reveal a non-eclipsing soft X-ray source and a deeply-eclipsing UV continuum. We will present the first ten years of optical spectral evolution of this system accompanied by ten years of BVRIJHK photometry, with an eye to deciphering the current nature of the system.

  5. trné elektrárny jako nový sociální fenomén

    Czech Academy of Sciences Publication Activity Database

    Frantál, Bohumil

    2007-01-01

    Roč. 13, č. 11 (2007), s. 19-20 ISSN 1211-0507. [Vítr a energie větru. Lesná, Vranov nad Dyjí, 09.10.2007-10.10.2007] Institutional research plan: CEZ:AV0Z30860518 Keywords : wind turbines * perception * public opinion * surveys * NIMBY syndrom * place marketing Subject RIV: AO - Sociology, Demography

  6. Phylogenetic relationships and generic delimitation of Eurasian Aster (Asteraceae: Astereae) inferred from ITS, ETS and trnL-F sequence data

    Science.gov (United States)

    Li, Wei-Ping; Yang, Fu-Sheng; Jivkova, Todorka; Yin, Gen-Shen

    2012-01-01

    Background and Aims The classification and phylogeny of Eurasian (EA) Aster (Asterinae, Astereae, Asteraceae) remain poorly resolved. Some taxonomists adopt a broad definition of EA Aster, whereas others favour a narrow generic concept. The present study aims to delimit EA Aster sensu stricto (s.s.), elucidate the phylogenetic relationships of EA Aster s.s. and segregate genera. Methods The internal and external transcribed spacers of nuclear ribosomal DNA and the plastid DNA trnL-F region were used to reconstruct the phylogeny of EA Aster through maximum parsimony and Bayesian analyses. Key Results The analyses strongly support an Aster clade including the genera Sheareria, Rhynchospermum, Kalimeris (excluding Kalimeris longipetiolata), Heteropappus, Miyamayomena, Turczaninowia, Rhinactinidia, eastern Asian Doellingeria, Asterothamnus and Arctogeron. Many well-recognized species of Chinese Aster s.s. lie outside of the Aster clade. Conclusions The results reveal that EA Aster s.s. is both paraphyletic and polyphyletic. Sheareria, Rhynchospermum, Kalimeris (excluding K. longipetiolata), Heteropappus, Miyamayomena, Turczaninowia, Rhinactinidia, eastern Asian Doellingeria, Asterothamnus and Arctogeron should be included in Aster, whereas many species of Chinese Aster s.s. should be excluded. The recircumscribed Aster should be divided into two subgenera and nine sections. Kalimeris longipetiolata, Aster batangensis, A. ser. Albescentes, A. series Hersileoides, a two-species group composed of A. senecioides and A. fuscescens, and a six-species group including A. asteroides, should be elevated to generic level. With the Aster clade, they belong to the Australasian lineages. The generic status of Callistephus should be maintained. Whether Galatella (including Crinitina) and Tripolium should remain as genera or be merged into a single genus remains to be determined. In addition, the taxonomic status of A. auriculatus and the A. pycnophyllus–A. panduratus clade remains

  7. BUSINNES MODEL OF CORS-TR (TUSAGA-AKTIF

    Directory of Open Access Journals (Sweden)

    S. Bakici

    2017-11-01

    Full Text Available CORS-TR (TUSAGA-Aktif (Turkish National Permanent GNSS Network – Active, serves location information at cm level accuracy in Turkey and TR Northern Cyprus in few seconds, where adequate numbers of GNSS satellites are observed and communication possibilities are present. No ground control points and benchmarks are necessary. There are 146 permanent GNSS stations within the CORS-TR System. Station data are transferred online to the main control center located in the Mapping Department of the General Directorate of Land Registry and Cadastre. CORS-TR System was established in 2008 and has been updated in software, hardware, communication and pricing areas from technical and administrative point of view in order to improve the system and provide better service to the users. Thus, the added value obtained from the CORS-TR System has been increased and contributed to the more efficient use of country resources. In this paper, how the technical, administrative and financial studies in the operation of the CORS-TR System were managed with a sustainable business model, studies for solving problems encountered in operating of the system, the cost / benefit analysis of the system and the sharing of experience gained from the perspective of how web-based applications are managed and the business model of the CORS-TR System are explained in detail.

  8. Businnes Model of Cors-Tr Tusaga-Aktif

    Science.gov (United States)

    Bakici, S.; Erkek, B.; İlbey, A.; Kulaksiz, E.

    2017-11-01

    CORS-TR (TUSAGA-Aktif (Turkish National Permanent GNSS Network - Active)), serves location information at cm level accuracy in Turkey and TR Northern Cyprus in few seconds, where adequate numbers of GNSS satellites are observed and communication possibilities are present. No ground control points and benchmarks are necessary. There are 146 permanent GNSS stations within the CORS-TR System. Station data are transferred online to the main control center located in the Mapping Department of the General Directorate of Land Registry and Cadastre. CORS-TR System was established in 2008 and has been updated in software, hardware, communication and pricing areas from technical and administrative point of view in order to improve the system and provide better service to the users. Thus, the added value obtained from the CORS-TR System has been increased and contributed to the more efficient use of country resources. In this paper, how the technical, administrative and financial studies in the operation of the CORS-TR System were managed with a sustainable business model, studies for solving problems encountered in operating of the system, the cost / benefit analysis of the system and the sharing of experience gained from the perspective of how web-based applications are managed and the business model of the CORS-TR System are explained in detail.

  9. Maximum credible accident analysis for TR-2 reactor conceptual design

    International Nuclear Information System (INIS)

    Manopulo, E.

    1981-01-01

    A new reactor, TR-2, of 5 MW, designed in cooperation with CEN/GRENOBLE is under construction in the open pool of TR-1 reactor of 1 MW set up by AMF atomics at the Cekmece Nuclear Research and Training Center. In this report the fission product inventory and doses released after the maximum credible accident have been studied. The diffusion of the gaseous fission products to the environment and the potential radiation risks to the population have been evaluated

  10. Investigating the taste in the city : Très très bon, gourmet stroll in Paris

    Directory of Open Access Journals (Sweden)

    Camille BRACHET

    2015-12-01

    Full Text Available In this paper, will be examined the potential of television regarding the representation of food and taste. The analysis focuses on a particular TV show, Très très bon, a weekend program broadcast on the channel Paris Première. Since the success of many TV programs has already shown that cooking and television can go together, it is interesting to try to understand the terms of staging which are very specific to Très très bon. For this purpose, the apparatus behind this TV program will be analysed in order to understand how the TV show seduces the viewer for whom any form of tasting remains technically impossible.

  11. A ironia trágica de Machado de Assis

    Directory of Open Access Journals (Sweden)

    Patrick Pessoa

    2007-04-01

    Full Text Available O texto defende, a partir de uma análise das Memórias póstumas de Brás Cubas, de Machado de Assis, que a ironia do autor deve ser lida como uma espécie de ironia trágica. A fundamentação dessa hipótese é realizada em três etapas: na primeira, apresenta-se o conceito de ironia trágica, como tematizado por Christoph Menke e Wayne Booth; na segunda, mostra-se como a noção de ironia trágica permite compreender a célebre definição de Lukács de que “a ironia é a objetividade do romance”; finalmente, o texto discute como o conceito de ironia trágica ao mesmo tempo esclarece e subverte as interpretações tradicionais da obra de Machado de Assis.

  12. Nucleotide sequence of soybean chloroplast DNA regions which contain the psb A and trn H genes and cover the ends of the large single copy region and one end of the inverted repeats.

    Science.gov (United States)

    Spielmann, A; Stutz, E

    1983-10-25

    The soybean chloroplast psb A gene (photosystem II thylakoid membrane protein of Mr 32 000, lysine-free) and the trn H gene (tRNAHisGUG), which both map in the large single copy region adjacent to one of the inverted repeat structures (IR1), have been sequenced including flanking regions. The psb A gene shows in its structural part 92% sequence homology with the corresponding genes of spinach and N. debneyi and contains also an open reading frame for 353 aminoacids. The aminoacid sequence of a potential primary translation product (calculated Mr, 38 904, no lysine) diverges from that of spinach and N. debneyi in only two positions in the C-terminal part. The trn H gene has the same polarity as the psb A gene and the coding region is located at the very end of the large single copy region. The deduced sequence of the soybean chloroplast tRNAHisGUG is identical with that of Zea mays chloroplasts. Both ends of the large single copy region were sequenced including a small segment of the adjacent IR1 and IR2.

  13. Forbruget af træer og buske i Danmark

    DEFF Research Database (Denmark)

    Jensen, Jan Svejgaard; Laursen, Allan Bach; Kjær, Erik Dahl

    Træer og buske er vigtige elementer i byen og landskabet, og i Danmark bruges der mellem 60 og 80 millioner vedplanter hvert år. Forbruget har været konstant stigende og der er sket store forskydninger i forbrugsmønstret i retning af større fokus på mangfoldighed og autencitet. Undersøgelsen...... klarlægger forbrugsmønstret for træer og buske og undersøger, hvad brugerne lægger vægt på i deres valg af planter....

  14. Canal de Mensagens de Trânsito

    OpenAIRE

    Egon Cervieri Guterres

    2010-01-01

    Informe Setorial: O Canal de Mensagens de Trânsito (Traffic Message Channel - TMC) é uma padronização internacional para a distribuição de informações (conteúdo) sobre a situação do trânsito urbano local e inter-regional, em tempo real, de forma eletrônica e diretamente aos motoristas. Traz para os cidadãos, em mensagens eletrônicas simples e acessíveis, informações sobre congestionamentos, acidentes, obras na pista, problemas climáticos (alagamentos, asfalto escorregadio, nevoeiro...) e desv...

  15. In-site coatings to reduce H and Tr permeation

    International Nuclear Information System (INIS)

    Stoever, D.; Buchkremer, H.P.; Hecker, R.; Jonas, H.; Schaefer, J.; Zink, U.; Forsyth, N.; Thiele, W.

    1982-01-01

    The main goal of this project is the development of protective coatings to reduce or prevent Tr and H permeation through the heat exchanger walls of HTR components. The tasks of the project are: Measurement of the permeation inhibition efficiency of oxidic coatings on the high-temperature- resistant heat exchanger walls; establishing the parameters influencing permeation by variation of the process gas and steam parameters, temperature and mechanical stress; characterisation of coatings and correlation of coating characteristics with permeation measurements; investigation of permeation and corrosion mechanisms; quantitative description of H and Tr permeation by means of mathematical/physical models. (orig./IHOE) [de

  16. Understanding TR binding to pMHC complexes: how does a TR scan many pMHC complexes yet preferentially bind to one.

    Directory of Open Access Journals (Sweden)

    Javed Mohammed Khan

    Full Text Available Understanding the basis of the binding of a T cell receptor (TR to the peptide-MHC (pMHC complex is essential due to the vital role it plays in adaptive immune response. We describe the use of computed binding (free energy (BE, TR paratope, pMHC epitope, molecular surface electrostatic potential (MSEP and calculated TR docking angle (θ to analyse 61 TR/pMHC crystallographic structures to comprehend TR/pMHC interaction. In doing so, we have successfully demonstrated a novel/rational approach for θ calculation, obtained a linear correlation between BE and θ without any "codon" or amino acid preference, provided an explanation for TR ability to scan many pMHC ligands yet specifically bind one, proposed a mechanism for pMHC recognition by TR leading to T cell activation and illustrated the importance of the peptide in determining TR specificity, challenging the "germline bias" theory.

  17. Trükitud majad : korterelamu Pariisis / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    1998-01-01

    Tänaste fassaadide keerukusest, paindlikkusest, vastuolulisusest. Trükitud klaasist fassaadi näiteks toodud elamu uue Pariisi Rahvusraamatukogu kõrval. Hoone pinna moodustavad suured värvitrükis klaaspaneelid, molle motiivid on laenatud renessanssmaalidelt. Katkematu lindina jooksevad ümber maja etteulatuvad metallrõdud.

  18. El cuento en Colombia. Viento de trópico

    Directory of Open Access Journals (Sweden)

    Javier Arias Ramírez

    1961-01-01

    Full Text Available No sería "Viento de Trópico", sino Cuentos Intensos, el nombre del libro que acaba de publicar José Francisco Socarrás. Hay tal dramatismo y tal densidad psicológica, propios de quien ha vivido en continuo y fatigoso indagar de la conciencia.

  19. Ajast ja arust trükikoda Kultuuritehases / Merit Kask

    Index Scriptorium Estoniae

    Kask, Merit

    2006-01-01

    Tallinna Kultuuritehase trükikojas toimunud kõrgtrükitehnikas käsilao õpikojast. Juhendaja inglise kunstnik Pete Nevin, osa võtsid Eesti Kunstiakadeemia tudengid (nimed), kelle tehtud tööd on samas näitusel

  20. Træernes rolle i et landbrugslandskab i Senegal

    DEFF Research Database (Denmark)

    Pedersen, Jens Christian

    2010-01-01

    Ved at gå ind i et eksisterende projektsamarbejde er det lykkedes Steen Christensen at gennemføre et vellykket feltarbejde i Senegal inden for et 6-måneders speciale. Resultaterne fra projektet vil kunne indgå som grundlag for en lokal forvaltning som tager sigte på at beskytte træerne som er en...

  1. Korroderede trådbindere i murværk

    DEFF Research Database (Denmark)

    Hansen, Klavs Feilberg

    Denne SBi-anvisning omdhandler korroderede trådbindere i hule mure og skalmure, og den nedstyrtningsfare som korrosionen kan medføre. Anvisningen beskriver metoder til at undersøge og vurdere problemet, og hvordan man kan eftermontere nye bindere. Anvisningen er rettet mod rådgivende ingeniører....

  2. Counsellors Respond to the DSM-IV-TR

    Science.gov (United States)

    Strong, Tom; Gaete, Joaquin; Sametband, Ines N.; French, Jared; Eeson, Jen

    2012-01-01

    The Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) is an administrative fact for many counsellors. This psychiatric approach to formulating client concerns runs counter to those used by counsellors of many approaches (e.g., systemic, feminist). Using an online survey of counsellors (N = 116), invited contributions to a website…

  3. TrED: the Trichophyton rubrum Expression Database

    Directory of Open Access Journals (Sweden)

    Liu Tao

    2007-07-01

    Full Text Available Abstract Background Trichophyton rubrum is the most common dermatophyte species and the most frequent cause of fungal skin infections in humans worldwide. It's a major concern because feet and nail infections caused by this organism is extremely difficult to cure. A large set of expression data including expressed sequence tags (ESTs and transcriptional profiles of this important fungal pathogen are now available. Careful analysis of these data can give valuable information about potential virulence factors, antigens and novel metabolic pathways. We intend to create an integrated database TrED to facilitate the study of dermatophytes, and enhance the development of effective diagnostic and treatment strategies. Description All publicly available ESTs and expression profiles of T. rubrum during conidial germination in time-course experiments and challenged with antifungal agents are deposited in the database. In addition, comparative genomics hybridization results of 22 dermatophytic fungi strains from three genera, Trichophyton, Microsporum and Epidermophyton, are also included. ESTs are clustered and assembled to elongate the sequence length and abate redundancy. TrED provides functional analysis based on GenBank, Pfam, and KOG databases, along with KEGG pathway and GO vocabulary. It is integrated with a suite of custom web-based tools that facilitate querying and retrieving various EST properties, visualization and comparison of transcriptional profiles, and sequence-similarity searching by BLAST. Conclusion TrED is built upon a relational database, with a web interface offering analytic functions, to provide integrated access to various expression data of T. rubrum and comparative results of dermatophytes. It is devoted to be a comprehensive resource and platform to assist functional genomic studies in dermatophytes. TrED is available from URL: http://www.mgc.ac.cn/TrED/.

  4. Modeller forudsiger klimarespons hos træer og buske

    DEFF Research Database (Denmark)

    Meilby, Henrik

    2015-01-01

    Modeller baseret på målinger af træer og buskes årringe afslører, hvilke klimatiske faktorer der lokalt er afgørende for deres vækst. Det kan hjælpe os med at forstå nogle af de ændringer, der sker i vegetationen, for eksempel i Grønland og i alpine områder. Med udgangspunkt i klimafrem- skrivnin......Modeller baseret på målinger af træer og buskes årringe afslører, hvilke klimatiske faktorer der lokalt er afgørende for deres vækst. Det kan hjælpe os med at forstå nogle af de ændringer, der sker i vegetationen, for eksempel i Grønland og i alpine områder. Med udgangspunkt i klimafrem...

  5. TrSDB: a proteome database of transcription factors

    Science.gov (United States)

    Hermoso, Antoni; Aguilar, Daniel; Aviles, Francesc X.; Querol, Enrique

    2004-01-01

    TrSDB—TranScout Database—(http://ibb.uab.es/trsdb) is a proteome database of eukaryotic transcription factors based upon predicted motifs by TranScout and data sources such as InterPro and Gene Ontology Annotation. Nine eukaryotic proteomes are included in the current version. Extensive and diverse information for each database entry, different analyses considering TranScout classification and similarity relationships are offered for research on transcription factors or gene expression. PMID:14681387

  6. Efficient inverse position transformation for TR 4000S robot manipulator

    Directory of Open Access Journals (Sweden)

    Kesheng Wang

    1989-04-01

    Full Text Available An efficient method is developed for computing the inverse kinematic position solution with a closed form for the TR 4000S spray painting robot manipulator with five degrees of freedom and non-spherical wrist construction. The inverse kinematic problem is defined as the transformation from Cartesian space to the joint space. The solution is based on the geometrical separation of the arm and wrist of a robot manipulator and shows that it is very systematic, efficient and easily derived.

  7. La Universidad de Costa Rica en tránsito

    Directory of Open Access Journals (Sweden)

    Badilla Saxe, Eleonora

    2012-02-01

    Full Text Available Resumen. La Universidad de Costa Rica en Tránsito es un artículo que pretende dar cuenta del tránsito que ha iniciado la institución en su camino hacia la transdisciplinariedad. Se presenta, en primera instancia, un contexto histórico y referentes teóricos que apuntan a que la Universidad en el Siglo XXI debe iniciar un tránsito, por una parte, de regreso a reflejar el significado de su origen: UNIVERSUS-A-UM (“todo”, “entero”, “universal” superando fragmentaciones y departamentalizaciones y, por otro, hacia una visión transdisciplinar, un pensamiento complejo en sintonía con las realidades biológicas, sociales y culturales del mundo en el siglo XXI. Y, ya que la transdisciplinariedad no se puede llevar a cabo más que en la acción y en la interacción con otros, se reporta sobre una serie de estrategias interconectadas que se están promoviendo Universidad de Costa Rica para ayudar a la institución a iniciar ese tránsito.Abstract. University of Costa Rica in Transit is an article that reports on the journey the institution has started on its path towards transdisciplinarity. On one way, back to the origen: universus (all, whole, universal, overcoming fragmentation and departamentalization. On the other towards a transdisciplinary vision and complex thinking in accordance with the new biological, social and cultural realities of our world. Interactive and interrelated strategies that are currently beeing promoted to stimulate the institution towards transdisciplinarity are reported here. It is important to remember that transdisciplinarity can only be reflected in action, and in the interaction with others.

  8. Trauma-Informed Guilt Reduction (TrIGR) Intervention

    Science.gov (United States)

    2017-10-01

    and maintenance of posttraumatic distress and a range of adverse outcomes, including posttraumatic stress disorder (PTSD), depression and suicidality ...posttraumatic distress and a range of adverse outcomes, including posttraumatic stress disorder (PTSD), depression and suicidality , and alcohol/substance use...PTSD symptoms, and depression with medium to large effect sizes. The overall objective of this study is to examine the efficacy of TrIGR in

  9. DW4TR: A Data Warehouse for Translational Research.

    Science.gov (United States)

    Hu, Hai; Correll, Mick; Kvecher, Leonid; Osmond, Michelle; Clark, Jim; Bekhash, Anthony; Schwab, Gwendolyn; Gao, De; Gao, Jun; Kubatin, Vladimir; Shriver, Craig D; Hooke, Jeffrey A; Maxwell, Larry G; Kovatich, Albert J; Sheldon, Jonathan G; Liebman, Michael N; Mural, Richard J

    2011-12-01

    The linkage between the clinical and laboratory research domains is a key issue in translational research. Integration of clinicopathologic data alone is a major task given the number of data elements involved. For a translational research environment, it is critical to make these data usable at the point-of-need. Individual systems have been developed to meet the needs of particular projects though the need for a generalizable system has been recognized. Increased use of Electronic Medical Record data in translational research will demand generalizing the system for integrating clinical data to support the study of a broad range of human diseases. To ultimately satisfy these needs, we have developed a system to support multiple translational research projects. This system, the Data Warehouse for Translational Research (DW4TR), is based on a light-weight, patient-centric modularly-structured clinical data model and a specimen-centric molecular data model. The temporal relationships of the data are also part of the model. The data are accessed through an interface composed of an Aggregated Biomedical-Information Browser (ABB) and an Individual Subject Information Viewer (ISIV) which target general users. The system was developed to support a breast cancer translational research program and has been extended to support a gynecological disease program. Further extensions of the DW4TR are underway. We believe that the DW4TR will play an important role in translational research across multiple disease types. Copyright © 2011 Elsevier Inc. All rights reserved.

  10. The Test Reactor Embrittlement Data Base (TR-EDB)

    International Nuclear Information System (INIS)

    Stallmann, F.W.; Kam, F.B.K.; Wang, J.A.

    1993-01-01

    The Test Reactor Embrittlement Data Base (TR-EDB) is part of an ongoing program to collect test data from materials irradiations to aid in the research and evaluation of embrittlement prediction models that are used to assure the safety of pressure vessels in power reactors. This program is being funded by the US Nuclear Regulatory Commission (NRC) and has resulted in the publication of the Power Reactor Embrittlement Data Base (PR-EDB) whose second version is currently being released. The TR-EDB is a compatible collection of data from experiments in materials test reactors. These data contain information that is not obtainable from surveillance results, especially, about the effects of annealing after irradiation. Other information that is only available from test reactors is the influence of fluence rates and irradiation temperatures on radiation embrittlement. The first version of the TR-EDB will be released in fall of 1993 and contains published results from laboratories in many countries. Data collection will continue and further updates will be published

  11. Fermentation of Foc TR4-infected bananas and Trichoderma spp.

    Science.gov (United States)

    Yang, J; Li, B; Liu, S W; Biswas, M K; Liu, S; Wei, Y R; Zuo, C W; Deng, G M; Kuang, R B; Hu, C H; Yi, G J; Li, C Y

    2016-10-17

    Fusarium wilt (also known as Panama disease) is one of the most destructive banana diseases, and greatly hampers the global production of bananas. Consequently, it has been very detrimental to the Chinese banana industry. An infected plant is one of the major causes of the spread of Fusarium wilt to nearby regions. It is essential to develop an efficient and environmentally sustainable disease control method to restrict the spread of Fusarium wilt. We isolated Trichoderma spp from the rhizosphere soil, roots, and pseudostems of banana plants that showed Fusarium wilt symptoms in the infected areas. Their cellulase activities were measured by endoglucanase activity, β-glucosidase activity, and filter paper activity assays. Safety analyses of the Trichoderma isolates were conducted by inoculating them into banana plantlets. The antagonistic effects of the Trichoderma spp on the Fusarium pathogen Foc tropical Race 4 (Foc TR4) were tested by the dual culture technique. Four isolates that had high cellulase activity, no observable pathogenicity to banana plants, and high antagonistic capability were identified. The isolates were used to biodegrade diseased banana plants infected with GFP-tagged Foc TR4, and the compost was tested for biological control of the infectious agent; the results showed that the fermentation suppressed the incidence of wilt and killed the pathogen. This study indicates that Trichoderma isolates have the potential to eliminate the transmission of Foc TR4, and may be developed into an environmentally sustainable treatment for controlling Fusarium wilt in banana plants.

  12. Marinization concept for the TRICEPT TR600 robot

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, A.; Aust, E.; Niemann, H.R.; Santos, J.F. dos [GKSS-Forschungszentrum Geesthacht GmbH (Germany). Inst. fuer Materialforschung; Hammerin, R.; Neumann, K.E. [Neos Robotics AB, Taeby (Sweden); Gibson, D. [National Hyperbaric Centre, Aberdeen (United Kingdom)

    1998-11-01

    The need for automated welding repair systems of marine structures, ship hulls and nuclear installations had lead to an increasing demand for subsea robots. Considering the application of friction welding to perform underwater repairs, a TRICEPT TR600 robot has been identified as the most suitable system to withstand the high reaction forces characteristic of this process. This study reviews initially the research and development work carried out at GKSS to modify and test a Siemens-MANUTEC robot. After a description of the TRICEPT TR600 robot a marinization concept is presented and discussed in detail. Problems of galvanic corrosion in seawater are addressed in a separate chapter. The deflection of the robot in subsea water currents is estimated with a worst-case calculation. (orig.) [Deutsch] Der Wunsch, Roboter auch unter Wasser einsetzen zu koennen, waechst mit steigendem Interesse nach automatisierten Schweissverfahren fuer Reparaturen an marinen Bauwerken, Schiffsruempfen und in Kernenergieanlagen. Fuer den Einsatz von Reibschweissverfahren fuer diese Reparaturen wurde der TRICEPT TR600-Roboter ausgewaehlt, da dieser auch den charakteristisch hohen Prozesskraeften widerstehen kann. Die notwendigen Modifikationen und Pruefungen werden beispielhaft anhand des bei der GKSS modifizierten Siemens-MANUTEC-Roboters vorgestellt. Nach einer Beschreibung des TRICEPT-Roboters werden die notwendigen Umbaumassnahmen detailliert dargestellt und diskutiert. Auf die Problematik der galvanischen Korrosion in Seewasser wird in einem gesonderten Kapitel naeher eingegangen. Zusaetzlich wird eine moegliche Ablenkung des Roboters durch Wasserstroemung ueberschlaegig berechnet. (orig.)

  13. The roles of testicular nuclear receptor 4 (TR4 in male fertility-priapism and sexual behavior defects in TR4 knockout mice

    Directory of Open Access Journals (Sweden)

    Bao Bo-Ying

    2011-10-01

    Full Text Available Abstract Background Successful reproductive efforts require the establishment of a situation favorable for reproduction that requires integration of both behavior and internal physiological events. TR4 nuclear receptor is known to be involved in male fertility via controlling spermatogenesis, yet its roles in regulating other biological events related to reproduction have not been completely revealed. Methods Male TR4 knockout (TR4-/- and wild type mice were used for the sexual behavior and penile dysfunction studies. Mice were sacrificed for histological examination and corresponding genes profiles were analyzed by quantitative RT-PCR. Reporter gene assays were performed. Results We describe an unexpected finding of priapism in TR4-/- mice. As a transcriptional factor, we demonstrated that TR4 transcriptionally modulates a key enzyme regulating penis erection and neuronal nitric oxide synthese NOS (nNOS. Thereby, elimination of TR4 results in nNOS reduction in both mRNA and protein levels, consequently may lead to erectile dysfunction. In addition, male TR4-/- mice display defects in sexual and social behavior, with increased fear or anxiety, as well as reduced mounting, intromission, and ejaculation. Reduction of ER alpha, ER beta, and oxytocin in the hypothalamus may contribute to defects in sexual behavior and stress response. Conclusions Together, these results provide in vivo evidence of important TR4 roles in penile physiology, as well as in male sexual behavior. In conjunction with previous finding, TR4 represents a key factor that controls male fertility via regulating behavior and internal physiological events.

  14. A short proof of a conjecture on the Tr-choice number of even cycles

    NARCIS (Netherlands)

    Sitters, R. A.

    In this note we prove that the Tr-choice number of the cycle C2n is equal to the Tr-choice number of the path (tree) on 4n - 1 vertices, i.e. Tr-ch(C2n) = [((4n - 2)/(4n - 1))(2r + 2)] + 1. This solves a recent conjecture of Alon and Zaks.

  15. Macrolide resistance gene erm(TR) and erm(TR)-carrying genetic elements in Streptococcus agalactiae: characterization of ICESagTR7, a new composite element containing IMESp2907.

    Science.gov (United States)

    Mingoia, Marina; Morici, Eleonora; Marini, Emanuela; Brenciani, Andrea; Giovanetti, Eleonora; Varaldo, Pietro E

    2016-03-01

    The objective of this study was to investigate macrolide-resistant Streptococcus agalactiae isolates harbouring erm(TR), an erm(A) gene subclass, with emphasis on their erm(TR)-carrying genetic elements. Four erm(TR)-carrying elements have been described to date: three closely related (ICE10750-RD.2, Tn1806 and ICESp1108) in Streptococcus pyogenes, Streptococcus pneumoniae and S. pyogenes, respectively; and one completely different (IMESp2907, embedded in ICESp2906 to form ICESp2905) in S. pyogenes. Seventeen macrolide-resistant erm(TR)-positive S. agalactiae isolates were phenotypically and genotypically characterized. Their erm(TR)-carrying elements were explored by analysing the distinctive recombination genes of known erm(TR)-carrying integrative and conjugative elements (ICEs) and by PCR mapping. The new genetic context and organization of IMESp2907 in S. agalactiae were explored using several experimental procedures and in silico analyses. Five isolates harboured ICE10750-RD.2/Tn1806, five isolates harboured ICESp1108 and five isolates bore unknown erm(TR)-carrying elements. The remaining two isolates, exhibiting identical serotypes and pulsotypes, harboured IMESp2907 in a new genetic environment, which was further investigated in one of the two isolates, SagTR7. IMESp2907 was circularizable in S. agalactiae, as described in S. pyogenes. The new IMESp2907 junctions were identified based on its site-specific integration; the att sites were almost identical to those in S. pyogenes. In strain SagTR7, erm(TR)-carrying IMESp2907 was embedded in an erm(TR)-less internal element related to ICE10750-RD.2/Tn1806, which, in turn, was embedded in an ICESde3396-like element. The resulting whole ICE, ICESagTR7 (∼129 kb), was integrated into the chromosome downstream of the rplL gene, and was excisable in circular form and transferable by conjugation. This is the first study exploring erm(TR)-carrying genetic elements in S. agalactiae. © The Author 2015. Published by

  16. Tallinna linna- ja gümnaasiumi trükikoda ehk 380 aastat trükikunsti Tallinnas / Aija Sakova-Merivee

    Index Scriptorium Estoniae

    Sakova-Merivee, Aija, 1980-

    2015-01-01

    Alanud aasta alguses esitlesid Tallinna Ülikooli Akadeemiline Raamatukogu ja Tallinna Linnaarhiiv ühist trükist „Tallinna linna- ja gümnaasiumi trükikoda (1634–1828). Näituse kataloog”. Autor annab ülevaate nii näitusest kui selle kataloogist

  17. Træ og Stål i Havvand

    DEFF Research Database (Denmark)

    Jensen, Jens Kristian Jehrbo

    Dette kompendium behandler træ- og stålkonstruktioners holdbarhed i marint miljø. Materialerne bliver udsat for kraftige påvirkninget· i form af bølgeslag, strø ninger, slid, nedbrydning og korrosion. Relevante mekanismer og beskyttelsessysleaer behandles . J~ftet tænkes anvendt ved undervisninge...... , spec ielt på anlægssektorens 6. semester, men andre interesserede er velkomne til at benytte det. Renskrivningen er foretaget af Tove Jensen, og Ingrid Christensen og Poul Skørbæk Sørensen har udført tegnearbejdet. Tak for veludført arbejde! Jens Kr . Jehcbo Jensen...

  18. Measuring heat transfer through TR-0 reactor fuel element

    International Nuclear Information System (INIS)

    Nemec, V.; Turzik, Z.; Vitek, M.

    1977-05-01

    The time course of temperatures of the peripheral and the central fuel pins of the TR-O reactor was studied during moderator temperature changes using a model. The formula T=Tsub(e)+(Tsub(o)-Tsub(e)).exp(-t/tsub(e)) applies, where T is the pin temperature, Tsub(o) the initial pin temperature, Tsub(e) is the steady-state bath temperature, tsub(e) the time constant of temperature equilibration and t the time required for a temperature change from value Tsub(o) to T. For the bath level height H=1 m the tsub(e) value for the central pin was determined to be 1.05 hours, for the peripheral pin 0.96 hour; for level height H=2 m the values were 2.1 and 2.12 hours, respectively. The dependence found will allow correcting the experimental results in measurements with heated moderator for fuel temperature changes. (Ha)

  19. A molecular phylogenetic and fruit evolutionary analysis of the major groups of the paleotropical woody bamboos (Gramineae: Bambusoideae) based on nuclear ITS, GBSSI gene and plastid trnL-F DNA sequences.

    Science.gov (United States)

    Yang, Han-Qi; Yang, Jun-Bo; Peng, Zhen-Hua; Gao, Jian; Yang, Yu-Ming; Peng, Sheng; Li, De-Zhu

    2008-09-01

    This study presented the first molecular phylogenetic analysis of the major clades of woody bamboos of the Old World tropics based on nuclear and chloroplast sequences (ITS, GBSSI and trnL-F). Sequence data from 53 species, representing 17 paleotropical woody bamboo genera, were analyzed using the maximum parsimony and Bayesian inference methods. All examined ingroup taxa were clustered into two clades, i.e., the Bambusinae+Dinochloa clade and the Melocanninae clade. The former clade included Bambusa, Bonia, Dendrocalamus, Dendrocalamopsis, Dinochloa, Gigantochloa, Molecalamus, Neomicrocalamus, Neosinocalamus, Oxytenanthera s. str. (sensu stricto), Racemobambos and Thyrsostachys. The Melocanninae clade consisted of Cephalostachyum, Leptocanna (better treated as part of Cephalostachyum), Melocanna, Pseudostachyum and Schizostachyum s. str. The subtribe Racemobambosinae and tribes Dendrocalameae and Oxytenanthereae were not supported and may be better placed in subtribe Bambusinae. The ovary characters seemed to be good criteria to distinguish these two clades. The reconstruction of ancestral fruit characters indicated that the bacoid caryopsis, namely, fleshy or berry-like fruits, was found to be scattered in three lineages of the examined paleotropical woody bamboos. Fruit characters are thus not reliable indicators of phylogeny and bacoid caryopsis likely represents a specialization for particular ecological conditions.

  20. Fabrication of PVDF-TrFE based bilayered PbTiO{sub 3}/PVDF-TrFE films capacitor

    Energy Technology Data Exchange (ETDEWEB)

    Nurbaya, Z., E-mail: nurbayazainal@gmail.com [NANO-ElecTronic Centre (NET), Faculty of Electrical Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor (Malaysia); Razak School of Engineering and Advanced Technology, Universiti Teknologi Malaysia, 54100 Kuala Lumpur (Malaysia); Wahid, M. H.; Rozana, M. D. [Faculty of Applied Sciences, Department of Polymer, Universiti Teknologi MARA, 40450 Shah Alam, Selangor (Malaysia); Annuar, I. [UiTM Sarawak Kampus Kota Samarahan, Jalan Meranek, 94300 Sarawak (Malaysia); Alrokayan, S. A. H.; Khan, H. A. [Department of Biochemistry, College of Science, Bldg. 5, King Saud University (KSU) P.O: 2454 Riyadh 11451 (Saudi Arabia); Rusop, M., E-mail: nanouitm@gmail.com [NANO-ElecTronic Centre (NET), Faculty of Electrical Engineering, Universiti Teknologi MARA, 40450 Shah Alam, Selangor (Malaysia); NANO-Sci Tech Centre (NST), Institute of Science, Universiti Teknologi MARA, 40450 Shah Alam, Selangor (Malaysia)

    2016-07-06

    Development of high performance capacitor is reaching towards new generation where the ferroelectric materials take places as the active dielectric layer. The motivation of this study is to produce high capacitance device with long life cycle. This was configured by preparing bilayered films where lead titanate as an active dielectric layer and stacked with the top dielectric layer, poly(vinyledenefluoride-trifluoroethylene). Both of them are being referred that have one in common which is ferroelectric behavior. Therefore the combination of ceramic and polymer ferroelectric material could perform optimum dielectric characteristic for capacitor applications. The fabrication was done by simple sol-gel spin coating method that being varied at spinning speed property for polymer layers, whereas maintaining the ceramic layer. The characterization of PVDF-TrFE/PbTiO3 was performed according to metal-insulator-metal stacked capacitor measurement which includes structural, dielectric, and ferroelectric measurement.

  1. Fabrication of PVDF-TrFE based bilayered PbTiO3/PVDF-TrFE films capacitor

    Science.gov (United States)

    Nurbaya, Z.; Wahid, M. H.; Rozana, M. D.; Annuar, I.; Alrokayan, S. A. H.; Khan, H. A.; Rusop, M.

    2016-07-01

    Development of high performance capacitor is reaching towards new generation where the ferroelectric materials take places as the active dielectric layer. The motivation of this study is to produce high capacitance device with long life cycle. This was configured by preparing bilayered films where lead titanate as an active dielectric layer and stacked with the top dielectric layer, poly(vinyledenefluoride-trifluoroethylene). Both of them are being referred that have one in common which is ferroelectric behavior. Therefore the combination of ceramic and polymer ferroelectric material could perform optimum dielectric characteristic for capacitor applications. The fabrication was done by simple sol-gel spin coating method that being varied at spinning speed property for polymer layers, whereas maintaining the ceramic layer. The characterization of PVDF-TrFE/PbTiO3 was performed according to metal-insulator-metal stacked capacitor measurement which includes structural, dielectric, and ferroelectric measurement.

  2. Três biografias quinhentistas da Rainha Santa Isabel

    Directory of Open Access Journals (Sweden)

    Helena Costa Toipa

    2016-12-01

    Full Text Available Dando continuidade aos esforços de canonização de D. Isabel de Aragão, D. João III obteve do Papa, em 1556, a autorização para alargar o culto da já beata D. Isabel a todo o reino. Solicitou, então, aos responsáveis dos mosteiros portugueses, nomeadamente à abadessa do mosteiro de Santa Clara, a composição de uma biografia da rainha, a partir de documentos existentes nesse mosteiro. Surgiram, então, três biografias, todas inspiradas nos referidos documentos: De Vita et Moribus Beatae Elisabethae Lusitaniae Reginae do padre jesuíta Pedro João Perpinhão; Vida e milagres da gloriosa Raynha sancta Ysabel, molher do catholico Rey dom Dinis sexto de Portugal, editada pelos mordomos da Confraria da Rainha Santa Isabel, e “ Vida da Bemaventurada sancta Isabel Raynha de Portugal”, de Frei Marcos de Lisboa, inclusa na Segunda Parte das suas Chronicas da Ordemdos Frades Menores.

  3. TR-EDB: Test Reactor Embrittlement Data Base, Version 1

    Energy Technology Data Exchange (ETDEWEB)

    Stallmann, F.W.; Wang, J.A.; Kam, F.B.K. [Oak Ridge National Lab., TN (United States)

    1994-01-01

    The Test Reactor Embrittlement Data Base (TR-EDB) is a collection of results from irradiation in materials test reactors. It complements the Power Reactor Embrittlement Data Base (PR-EDB), whose data are restricted to the results from the analysis of surveillance capsules in commercial power reactors. The rationale behind their restriction was the assumption that the results of test reactor experiments may not be applicable to power reactors and could, therefore, be challenged if such data were included. For this very reason the embrittlement predictions in the Reg. Guide 1.99, Rev. 2, were based exclusively on power reactor data. However, test reactor experiments are able to cover a much wider range of materials and irradiation conditions that are needed to explore more fully a variety of models for the prediction of irradiation embrittlement. These data are also needed for the study of effects of annealing for life extension of reactor pressure vessels that are difficult to obtain from surveillance capsule results.

  4. Georges et les trésors du cosmos

    CERN Document Server

    Hawking, Lucy; Parsons, Gary

    2011-01-01

    Les voisins excentriques de Georges, Annie et Eric, ont déménagé en Floride à l'agence Spatiale Globale. Là-bas, Eric s'occupe de son nouveau robot, Homer, qui doit détécter les signes de vie sur Mars. Mais bientôt, Georges reçoit un e-mail : Annie lui demande de la rejoindre au plus vite pour une " mission cosmique " secrète. La jeune fille est persuadée qu'il se passe de drôles de choses sur Mars, car Homer vient de recevoir un message extraterrestre ! Georges et Anne (avec l'aide d'Emmett, un petit garçon bizarre) décident de réparer Cosmos, leur super-ordinateur, et d'aller voir par eux-mêmes... Emmaillotés dans des combinaisons spéciales, ils se lancent alors dans une fabuleuse chasse aux trésors sur Mars, sur les lunes de Saturne, puis sur Titan, avant de se perdre en orbite autour d'Alpha Centauri B... Mais avant de pouvoir élucider le mystère du message extraterrestre, Georges et Annie devront se livrer à une bataille spatiale acharnée qui mettra leur vie en danger, ainsi que ce...

  5. Flexible piezoelectric nanogenerators based on PVDF-TrFE nanofibers

    Science.gov (United States)

    Serairi, Linda; Gu, Long; Qin, Yong; Lu, Yingxian; Basset, Philippe; Leprince-Wang, Yamin

    2018-01-01

    In this paper, electrospun piezoelectric PVDF-TrFE nanofibers were used for the fabrication of two types of flexible nanogenerator (NG) devices based on the direct piezoelectric effect, allowing the conversion of mechanical energy into electrical energy. The first one is composed of quite well aligned thin film nanofibers of about 35 μm and the second one is composed of random nanofibers of about 50 μm. The influence of the applied stress and strain rate on the output for both types of NG was studied. It is shown that the pulse peaks generated by NG increase with the applied mechanical strain frequency, the generated output is also proportional to the applied stress amplitude. The first NG loaded in bending mode can generate a maximum voltage of 270 mV. By connecting two devices in series/parallel, the voltage/current value could be multiplied by two. The second NG which was biased in compression mode using a shaker controlled by a force sensor, can generate a potential of about 7 V under 3.6 N applied force.

  6. TR-EDB: Test Reactor Embrittlement Data Base, Version 1

    International Nuclear Information System (INIS)

    Stallmann, F.W.; Wang, J.A.; Kam, F.B.K.

    1994-01-01

    The Test Reactor Embrittlement Data Base (TR-EDB) is a collection of results from irradiation in materials test reactors. It complements the Power Reactor Embrittlement Data Base (PR-EDB), whose data are restricted to the results from the analysis of surveillance capsules in commercial power reactors. The rationale behind their restriction was the assumption that the results of test reactor experiments may not be applicable to power reactors and could, therefore, be challenged if such data were included. For this very reason the embrittlement predictions in the Reg. Guide 1.99, Rev. 2, were based exclusively on power reactor data. However, test reactor experiments are able to cover a much wider range of materials and irradiation conditions that are needed to explore more fully a variety of models for the prediction of irradiation embrittlement. These data are also needed for the study of effects of annealing for life extension of reactor pressure vessels that are difficult to obtain from surveillance capsule results

  7. Spectroscopic markers of the TR quaternary transition in human hemoglobin.

    Science.gov (United States)

    Schirò, Giorgio; Cammarata, Marco; Levantino, Matteo; Cupane, Antonio

    2005-04-01

    In this work, we use a sol-gel protocol to trap and compare the R and T quaternary states of both the deoxygenated (deoxyHb) and carbonmonoxide (HbCO) derivatives of human hemoglobin. The near infrared optical absorption band III and the infrared CO stretching band are used to detect the effect of quaternary structure on the spectral properties of deoxyHb and HbCO; comparison with myoglobin allows for an assessment of tertiary and quaternary contributions to the measured band shifts. The RT transition is shown to cause a blue shift of the band III by approximately 35 cm(-1) for deoxyHb and a red shift of the CO stretching band by only approximately 0.3 cm(-1) for HbCO. This clearly shows that quaternary structure changes are transmitted to the heme pocket and that effects on deoxyHb are much larger than on HbCO, at least as far as the band energies are concerned. Experiments performed in the ample temperature interval of 300-10K show that the above quaternary structure effects are "static" and do not influence the dynamic properties of the heme pocket, at least as probed by the temperature dependence of band III and of the CO stretching band. The availability of quaternary structure sensitive spectroscopic markers and the quantitative measurement of the quaternary structure contribution to band shifts will be of considerable help in the analysis of flash-photolysis experiments on hemoglobin. Moreover, it will enable one to characterize the dynamic properties of functionally relevant hemoglobin intermediates and to study the kinetics of both the T-->R and R-->T quaternary transitions through time-resolved spectroscopy.

  8. In-situ hybridization based quantification of hTR: a possible biomarker in malignant melanoma

    DEFF Research Database (Denmark)

    Vagner, Josephine; Steiniche, Torben; Stougaard, Magnus

    2015-01-01

    thickness suggesting that hTR might be a valuable biomarker in MM. Furthermore, as ISH-based detection requires presence of both hTR and the reverse transcriptase (hTERT) it might be an indicator of active telomerase and thus have future relevance as a predictive biomarker for anti-telomerase treatment....

  9. The Orphan Nuclear Receptor TR4 Is a Vitamin A-activated Nuclear Receptor

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, X. Edward; Suino-Powell, Kelly M.; Xu, Yong; Chan, Cee-Wah; Tanabe, Osamu; Kruse, Schoen W.; Reynolds, Ross; Engel, James Douglas; Xu, H. Eric (Michigan-Med); (Van Andel)

    2015-11-30

    Testicular receptors 2 and 4 (TR2/4) constitute a subgroup of orphan nuclear receptors that play important roles in spermatogenesis, lipid and lipoprotein regulation, and the development of the central nervous system. Currently, little is known about the structural features and the ligand regulation of these receptors. Here we report the crystal structure of the ligand-free TR4 ligand binding domain, which reveals an autorepressed conformation. The ligand binding pocket of TR4 is filled by the C-terminal half of helix 10, and the cofactor binding site is occupied by the AF-2 helix, thus preventing ligand-independent activation of the receptor. However, TR4 exhibits constitutive transcriptional activity on multiple promoters, which can be further potentiated by nuclear receptor coactivators. Mutations designed to disrupt cofactor binding, dimerization, or ligand binding substantially reduce the transcriptional activity of this receptor. Importantly, both retinol and retinoic acid are able to promote TR4 to recruit coactivators and to activate a TR4-regulated reporter. These findings demonstrate that TR4 is a ligand-regulated nuclear receptor and suggest that retinoids might have a much wider regulatory role via activation of orphan receptors such as TR4.

  10. TR146 cells grown on filters as a model of human buccal epithelium

    DEFF Research Database (Denmark)

    Nielsen, H M; Rassing, M R; Nielsen, Hanne Mørck

    2000-01-01

    The objective of the present study was to evaluate the TR146 cell culture model as an in vitro model of human buccal epithelium. For this purpose, the permeability of water, mannitol and testosterone across the TR146 cell culture model was compared to the permeability across human, monkey...

  11. The anti-inflammatory effect of TR6 on LPS-induced mastitis in mice.

    Science.gov (United States)

    Hu, Xiaoyu; Fu, Yunhe; Tian, Yuan; Zhang, Zecai; Zhang, Wenlong; Gao, Xuejiao; Lu, Xiaojie; Cao, Yongguo; Zhang, Naisheng

    2016-01-01

    [TRIAP]-derived decoy peptides have anti-inflammatory properties. In this study, we synthesized a TRIAP-derived decoy peptide (TR6) containing, the N-terminal portion of the third helical region of the [TIRAP] TIR domain (sequence "N"-RQIKIWFQNRRMKWK and -KPGFLRDPWCKYQML-"C"). We evaluated the effects of TR6 on lipopolysaccharide-induced mastitis in mice. In vivo, the mastitis model was induced by LPS administration for 24h, and TR6 treatment was initiated 1h before or after induction of LPS. In vitro, primary mouse mammary epithelial cells and neutrophils were used to investigate the effects of TR6 on LPS-induced inflammatory responses. The results showed that TR6 significantly inhibited mammary gland hisopathologic changes, MPO activity, and LPS-induced production of TNF-α, IL-1β and IL-6. In vitro, TR6 significantly inhibited LPS-induced TNF-α and IL-6 production and phosphorylation of NF-κB and MAPKs. In conclusion, this study demonstrated that the anti-inflammatory effect of TR6 against LPS-induced mastitis may be due to its ability to inhibit TLR4-mediated NF-κB and MAPK signaling pathways. TR6 may be a promising therapeutic reagent for mastitis treatment. Copyright © 2015. Published by Elsevier B.V.

  12. Optimization and Verification of the TR-MAC Protocol for Wireless Sensor Networks

    NARCIS (Netherlands)

    Morshed, S.; Heijenk, Geert

    2015-01-01

    Energy-efficiency is an important requirement in the design of communication protocols for wireless sensor networks (WSN). TR-MAC is an energy-efficient medium access control (MAC) layer protocol for low power WSN that exploits transmitted-reference (TR) modulation in the physical layer. The

  13. A 3x1 integrated pyroelectric sensor based on VDF/TrFE copolymer

    NARCIS (Netherlands)

    Setiadi, D.; Setiadi, D.; Sarro, P.M.; Regtien, Paulus P.L.

    1996-01-01

    This paper presents an integrated pyroelectric sensor based on a vinylidene fluoride¿trifluoroethylene (VDF/TrFE) copolymer. A silicon substrate that contains field-effect transistor (FET) readout electronics is coated with the VDF/TrFE copolymer film using a spin-coating technique. On-chip poling

  14. Realization of an integrated VDF/TrFE copolymer-on-silicon pyroelectric sensor

    NARCIS (Netherlands)

    Setiadi, D.; Setiadi, D.; Regtien, Paulus P.L.; Sarro, P.M.

    1995-01-01

    An integrated pyroelectric sensor based on a vinylidene fluoride trifluoroethylene (VDF/TrFE) copolymer is presented. A silicon substrate that contains FET readout electronics is coated with the VDF/TrFE copolymer film using a spin-coating technique. On-chip poling of the copolymer has been applied

  15. Xylan oligosaccharides and cellobiohydrolase I (TrCeI7A) interaction and effect on activity

    DEFF Research Database (Denmark)

    Baumann, Martin Johannes; Borch, Kim; Westh, Peter

    2011-01-01

    and an enzyme variant without the cellulose-binding domain (CBM). Results We studied the binding of XOSs to TrCel7A by isothermal titration calorimetry. We found that XOSs bind to TrCel7A and that the affinity increases commensurate with XOS length. The CBM, on the other hand, did not affect the affinity...

  16. The design of an asynchronous Tiny RISC TM/TR4101 microprocessor core

    DEFF Research Database (Denmark)

    Christensen, Kåre Tais; Jensen, P.; Korger, P.

    1998-01-01

    This paper presents the design of an asynchronous version of the TR4101 embedded microprocessor core developed by LSI Logic Inc. The asynchronous processor, called ARISC, was designed using the same CAD tools and the same standard cell library that was used to implement the TR4101. The paper repo...

  17. TR32DB - Management of Research Data in a Collaborative, Interdisciplinary Research Project

    Science.gov (United States)

    Curdt, Constanze; Hoffmeister, Dirk; Waldhoff, Guido; Lang, Ulrich; Bareth, Georg

    2015-04-01

    The management of research data in a well-structured and documented manner is essential in the context of collaborative, interdisciplinary research environments (e.g. across various institutions). Consequently, set-up and use of a research data management (RDM) system like a data repository or project database is necessary. These systems should accompany and support scientists during the entire research life cycle (e.g. data collection, documentation, storage, archiving, sharing, publishing) and operate cross-disciplinary in interdisciplinary research projects. Challenges and problems of RDM are well-know. Consequently, the set-up of a user-friendly, well-documented, sustainable RDM system is essential, as well as user support and further assistance. In the framework of the Transregio Collaborative Research Centre 32 'Patterns in Soil-Vegetation-Atmosphere Systems: Monitoring, Modelling, and Data Assimilation' (CRC/TR32), funded by the German Research Foundation (DFG), a RDM system was self-designed and implemented. The CRC/TR32 project database (TR32DB, www.tr32db.de) is operating online since early 2008. The TR32DB handles all data, which are created by the involved project participants from several institutions (e.g. Universities of Cologne, Bonn, Aachen, and the Research Centre Jülich) and research fields (e.g. soil and plant sciences, hydrology, geography, geophysics, meteorology, remote sensing). Very heterogeneous research data are considered, which are resulting from field measurement campaigns, meteorological monitoring, remote sensing, laboratory studies and modelling approaches. Furthermore, outcomes like publications, conference contributions, PhD reports and corresponding images are regarded. The TR32DB project database is set-up in cooperation with the Regional Computing Centre of the University of Cologne (RRZK) and also located in this hardware environment. The TR32DB system architecture is composed of three main components: (i) a file-based data

  18. Luchas migrantes en contextos de tránsito migratorio, el caso del movimiento migrante centroamericano

    OpenAIRE

    Huerta, Amarela Varela

    2016-01-01

    Resumen Este texto aborda un ejemplo concreto de organización de migrantes, el Movimiento Migrante Mesoamericano, que trabaja por los derechos de los migrantes en tránsito por México, de forma coordinada con organizaciones y familiares de migrantes víctimas de desaparición en su tránsito hacia Estados Unidos. Este estudio de caso es un ejemplo de luchas migrantes en contextos de tránsito, tipo específico de movimiento social que ha sido poco abordado en la literatura que piensa la acción cole...

  19. Kompleksnost vzvodov strategije prodajnih poti v izvoznem trženju

    OpenAIRE

    Tominc, Polona; Jurše, Milan; Jager, Jerneja

    2015-01-01

    Distribucije v raziskavi ne obravnavamo zgolj kot ene od sestavin trženjskega spleta podjetja, temveč kot strateško razsežnost razvoja tržne pozicije na izbranih tujih trgih, katere cilj ni zagotoviti zgolj prodajo izdelkov podjetja, temveč ustvariti distribucijski sistem, ki bo podjetju zagotavljal rast prodaje in krepil konkurenčne prednosti na trgu. Na izbranem vzorcu slovenskih proizvodnih podjetij smo preverjali povezanost med izvozno tržno naravnanostjo podjetja, inovativnostjo, odnosi ...

  20. TR146 cells grown on filters as a model of human buccal epithelium

    DEFF Research Database (Denmark)

    Mørck Nielsen, H; Rømer Rassing, M; Nielsen, Hanne Mørck

    2000-01-01

    cell culture model, and human and porcine buccal epithelium were compared. The esterase activity in the intact cell culture model and in the porcine buccal mucosa was compared. Further, the TR146 cell culture model was used to study the permeability rate and metabolism of leu-enkephalin. The activity...... of the three enzymes in the TR146 homogenate supernatants was in the same range as the activity in homogenate supernatants of human buccal epithelium. In the TR146 cell culture model, the activity of aminopeptidase (13.70+/-2.10 nmol/min per mg protein) was approx. four times the activity of carboxypeptidase...

  1. A case report and brief literature review of Klippel-Trénaunay syndrome

    Directory of Open Access Journals (Sweden)

    Choudhary MG

    2012-05-01

    Full Text Available Madan Gopal Choudhary, Zia Ul Haq, Ram Narayan Sehra, Chandra Kumar ChaharDepartment of Paediatrics, Sardar Patel Medical College and P.B.M Hospital, Rajasthan, IndiaAbstract: Klippel-Trénaunay syndrome is a rare disorder characterized by the triad of vascular malformations, venous varicosities, and bone and soft-tissue hypertrophy. We present a case of Klippel-Trénaunay syndrome with limb hypertrophy, port-wine stains, angiokeratoma, and venous varicosities in the limbs.Keywords: Klippel-Trénaunay syndrome, sporadic, venous varicosities, port-wine stain, angiokeratoma

  2. Turkey's regulatory plans for high enriched to low enriched conversion of TR-2 reactor core

    International Nuclear Information System (INIS)

    Guelol Oezdere, Oya

    2003-01-01

    Turkey is a developing country and has three nuclear facilities two of which are research reactors and one pilot fuel production plant. One of the two research reactors is TR-2 which is located in Cekmece site in Istanbul. TR-2 Reactor's core is composed of both high enriched and low enriched fuel and from high enriched to low enriched core conversion project will take place in year 2005. This paper presents the plans for drafting regulations on the safety analysis report updates for high enriched to low enriched core conversion of TR-2 reactor, the present regulatory structure of Turkey and licensing activities of nuclear facilities. (author)

  3. Draft Genome Sequence of Clostridium mangenotii TR, Isolated from the Fecal Material of a Timber Rattlesnake

    Science.gov (United States)

    Cochran, Philip A.; Dowd, Scot E.; Andersen, Kylie; Anderson, Nichole; Brennan, Rachel; Brook, Nicole; Callaway, Tracie; Diamante, Kimberly; Duberstine, Annie; Fitch, Karla; Freiheit, Heidi; Godlewski, Chantel; Gorman, Kelly; Haubrich, Mark; Hernandez, Mercedes; Hirtreiter, Amber; Ivanoski, Beth; Jaminet, Xochitl; Kirkpatrick, Travis; Kratowicz, Jennifer; Latus, Casey; Leable, Tiegen; Lingafelt, Nicole; Lowe, DeAnna; Lowrance, Holly; Malsack, Latiffa; Mazurkiewicz, Julie; Merlos, Persida; Messley, Jamie; Montemurro, Dawn; Nakitare, Samora; Nelson, Christine; Nye, Amber; Pazera, Valerie; Pierangeli, Gina; Rellora, Ashley; Reyes, Angelica; Roberts, Jennifer; Robins, Shadara; Robinson, Jeshannah; Schultz, Alissa; Seifert, Sara; Sigler, Elona; Spangler, Julie; Swift, Ebony; TenCate, Rebecca; Thurber, Jessica; Vallee, Kristin; Wamboldt, Jennifer; Whitten, Shannon; Woods, De’andrea; Wright, Amanda; Yankunas, Darin

    2014-01-01

    Here, we report the draft genome sequence of Clostridium mangenotii strain TR, which was isolated from the fecal material of a timber rattlesnake. This bacterium is nonpathogenic but contains 68 genes involved in virulence, disease, and defense. PMID:24407632

  4. X Congreso Panamericano de Ingeniería de Tránsito y Transporte

    OpenAIRE

    Luis Antonio Lindau; Orlando Strambi

    2010-01-01

    No texto o autor apresenta os temas que foram apresentados e discutidos no X PANAM, Congreso Panamericano de Ingeniería de Tránsito y Transporte, realizado em setembro de 1998 em Santander, na Espanha.

  5. Kinematic MRI using short TR single shot fast spin echo (SSFSE) in evaluating swallowing

    Energy Technology Data Exchange (ETDEWEB)

    Isogai, Satoshi; Takehara, Yasuo; Isoda, Haruo; Kodaira, Nami; Masunaga, Hatsuko; Ozawa, Fukujirou; Kaneko, Masao [Hamamatsu Univ. School of Medicine, Shizuoka (Japan); Nozaki, Atsushi; Kabasawa, Hiroyuki

    1999-03-01

    The utility of short TR single shot fast spin echo (SSFSE) MR imaging for evaluating swallowing was determined. Five healthy volunteers underwent kinematic MR imaging of swallowing with a 1.5 T MR scanner using the short TR (300 ms) SSFSE sequence. Twenty phases of sagittal sections were acquired within 6 sec, where the temporal resolution was 300 ms. For oral contrast medium, we used prune yogurt juice with Fe added. The image contrast of short TR SSFSE was found to be somewhere like that of T1-weighted images. In all cases, both the buccal and pharyngeal stages of swallowing were successfully depicted. The Fe-added prune yogurt juice performed as a positive contrast medium and helped determine anatomical structures in the buccal stage. Short TR (300 ms) SSFSE was useful in evaluating swallowing. The combined use of Fe-added prune yogurt juice was helpful in enhancing the surface of the oropharynx. (author)

  6. Kinematic MRI using short TR single shot fast spin echo (SSFSE) in evaluating swallowing

    International Nuclear Information System (INIS)

    Isogai, Satoshi; Takehara, Yasuo; Isoda, Haruo; Kodaira, Nami; Masunaga, Hatsuko; Ozawa, Fukujirou; Kaneko, Masao; Nozaki, Atsushi; Kabasawa, Hiroyuki

    1999-01-01

    The utility of short TR single shot fast spin echo (SSFSE) MR imaging for evaluating swallowing was determined. Five healthy volunteers underwent kinematic MR imaging of swallowing with a 1.5 T MR scanner using the short TR (300 ms) SSFSE sequence. Twenty phases of sagittal sections were acquired within 6 sec, where the temporal resolution was 300 ms. For oral contrast medium, we used prune yogurt juice with Fe added. The image contrast of short TR SSFSE was found to be somewhere like that of T1-weighted images. In all cases, both the buccal and pharyngeal stages of swallowing were successfully depicted. The Fe-added prune yogurt juice performed as a positive contrast medium and helped determine anatomical structures in the buccal stage. Short TR (300 ms) SSFSE was useful in evaluating swallowing. The combined use of Fe-added prune yogurt juice was helpful in enhancing the surface of the oropharynx. (author)

  7. Gåsetrekket i Vesterålen og Nord-Trøndelag 2004

    DEFF Research Database (Denmark)

    Tombre, I.; Madsen, J.; Bakken, J.

    for the goose species pink-footed goose Anser brachyrhynchus, barnacle goose Branta leucopsis and greylag goose Anser anser. The present report summarises goose registrations in some of the municipalities involved; Steinkjer and Inderøy in Nord-Trøndelag, Mid-Norway (pink-footed goose), and Sortland...... in Vesterålen, Northern Norway (pink-footed goose and barnacle goose). Registrations in the Nord-Trøndelag municipalities, Verdal and Levanger, are also included. Pink-footed and barnacle geese stage in Norway during spring on their way to their breeding grounds in Svalbard. In Trøndelag, the spring...... estimate of 43 000). This is probably an underestimate due to all hiding possibilities in the region, and it is assumed that at least 75 % of the Svalbard population of pink-footed goose stayed in Nord-Trøndelag in early May. Intensive scaring of geese registered at several locations in the county...

  8. On an integral representation of the function Tr(exp(A-lambdaB))

    Energy Technology Data Exchange (ETDEWEB)

    Mehta, M L [CEA Centre d' Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France). Service de Physique Theorique; Kumar, K

    1976-02-01

    The conjecture that Tr(exp(A-lambdaB)) can be written as a Laplace transform with a positive measure is proved for a certain class of matrices A and B. A few remarks are made about the undecided cases.

  9. Space-charge-mediated anomalous ferroelectric switching in P(VDF-TrEE) polymer films

    KAUST Repository

    Hu, Weijin; Wang, Zhihong; Du, Yuanmin; Zhang, Xixiang; Wu, Tao

    2014-01-01

    We report on the switching dynamics of P(VDF-TrEE) copolymer devices and the realization of additional substable ferroelectric states via modulation of the coupling between polarizations and space charges. The space-charge-limited current

  10. Herpesvirus telomerase RNA (vTR with a mutated template sequence abrogates herpesvirus-induced lymphomagenesis.

    Directory of Open Access Journals (Sweden)

    Benedikt B Kaufer

    2011-10-01

    Full Text Available Telomerase reverse transcriptase (TERT and telomerase RNA (TR represent the enzymatically active components of telomerase. In the complex, TR provides the template for the addition of telomeric repeats to telomeres, a protective structure at the end of linear chromosomes. Human TR with a mutation in the template region has been previously shown to inhibit proliferation of cancer cells in vitro. In this report, we examined the effects of a mutation in the template of a virus encoded TR (vTR on herpesvirus-induced tumorigenesis in vivo. For this purpose, we used the oncogenic avian herpesvirus Marek's disease virus (MDV as a natural virus-host model for lymphomagenesis. We generated recombinant MDV in which the vTR template sequence was mutated from AATCCCAATC to ATATATATAT (vAU5 by two-step Red-mediated mutagenesis. Recombinant viruses harboring the template mutation replicated with kinetics comparable to parental and revertant viruses in vitro. However, mutation of the vTR template sequence completely abrogated virus-induced tumor formation in vivo, although the virus was able to undergo low-level lytic replication. To confirm that the absence of tumors was dependent on the presence of mutant vTR in the telomerase complex, a second mutation was introduced in vAU5 that targeted the P6.1 stem loop, a conserved region essential for vTR-TERT interaction. Absence of vTR-AU5 from the telomerase complex restored virus-induced lymphoma formation. To test if the attenuated vAU5 could be used as an effective vaccine against MDV, we performed vaccination-challenge studies and determined that vaccination with vAU5 completely protected chickens from lethal challenge with highly virulent MDV. Taken together, our results demonstrate 1 that mutation of the vTR template sequence can completely abrogate virus-induced tumorigenesis, likely by the inhibition of cancer cell proliferation, and 2 that this strategy could be used to generate novel vaccine candidates

  11. Magnetic fluctuations on TR{sub 3}Ba{sub 5}Cu{sub 8}O{sub δ} (TR=Ho, Y and Yb) superconducting system

    Energy Technology Data Exchange (ETDEWEB)

    Supelano, G.I., E-mail: ivan.supelano@uptc.edu.co [Grupo de Superficies Electroquímica y Corrosión, Universidad Pedagógica y Tecnológica de Colombia (Colombia); Sarmiento Santos, A. [Grupo de Superficies Electroquímica y Corrosión, Universidad Pedagógica y Tecnológica de Colombia (Colombia); Parra Vargas, C.A. [Grupo de Física de Materiales, Universidad Pedagógica y Tecnológica de Colombia (Colombia)

    2014-12-15

    In this work, we report the production of TR{sub 3}Ba{sub 5}Cu{sub 8}O{sub δ} (TR=Ho, Y and Yb) superconducting system using a usual solid state reaction method. The irreversibility line and the analysis of magnetization fluctuations for TR{sub 3}Ba{sub 5}Cu{sub 8}O{sub δ} (TR=Ho, Y and Yb) system were investigated. The curves of magnetization ZFC–FC were measured in magnetic fields of the 100–4000 Oe to obtain the values for T{sup ⁎} and T{sub C} temperatures. The penetration depth and the coherence length parameters as a function of the applied magnetic field were obtained. The data of the magnetization excess ΔM(T, H) was analyzed from the curves of magnetization as a function of logarithm of applied field for different values of temperature in the corresponding range. The Bulavskii, Ledvij and Kogan theory was employed for this purpose which considers fluctuations effects in the free energy and into the equilibrium magnetization.

  12. Was bedeutet Trägheit? Begriff und Wirkung der Trägheit im Rahmen des Wechselverhaltens von Konsumenten im Strommarkt

    NARCIS (Netherlands)

    Henseler, Jörg

    2006-01-01

    In Wissenschaft und Praxis wird die Trägheit der Konsumenten als Ursache der geringen Wechselrate im deutschen Strommarkt für Haushaltskunden diskutiert. Der vorliegende Beitrag arbeitet heraus, dass es sich bei dieser Argumentation entweder um eine Tautologie oder ein Synomym für den Verbleib in

  13. Kirjastamine 21. sajandil - trüki oma raamat ise / Rivo Sarapik, Andres Kütt, Stanislav Sinyagin

    Index Scriptorium Estoniae

    Sarapik, Rivo, 1981-

    2008-01-01

    Väikesetiraa̓iliste trükiste kirjastamise etappidest ja soovitusi trükifirmade valikul internetis ning erinevate inimeste kogemusi fotoraamatu või fotoajakirja trükkimisel, kasutades Blurb.com või Lulu.com teenust. Kuni väljatrükini on teenus valdavalt tasuta

  14. Effekter af træstøv; inflammation, gentoksicitet og cancer

    DEFF Research Database (Denmark)

    Lange, Jette Bornholdt

    2008-01-01

    lokaliseret i næse og bihuler. Især erhvervsmæssig udsæt-telse for hårde træsorter som eg, birk, bøg eller teak er associeret med sinonasal cancer og luftvejssymptomer. Trods talrige epidemiologiske studier af træstøvs helbredseffekter er forståelsen af de bagvedliggende mekanismer meget begrænset. I år 2000...

  15. Nonlinear elastic wave spectroscopy in symbiosis with time reversal for localization of defects: TR-NEWS

    Czech Academy of Sciences Publication Activity Database

    Dos Santos, S.; Vejvodová, Šárka; Převorovský, Zdeněk

    2009-01-01

    Roč. 19, č. 2 (2009), s. 14-14 ISSN 1213-3825. [NDT in PROGRESS. 12.11.2009-14.11.2009, Praha] R&D Projects: GA ČR GA106/07/1393; GA MPO(CZ) FR-TI1/274 Institutional research plan: CEZ:AV0Z20760514 Keywords : nonlinear elastic wave spectroscopy (NEWS) * ESAM * time reversal (TR) * TR-NEWS imaging * tomography * DORT Subject RIV: BI - Acoustics

  16. Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology.

    Directory of Open Access Journals (Sweden)

    Marcela Montes de Oca

    2016-01-01

    Full Text Available Tumor necrosis factor (TNF is critical for controlling many intracellular infections, but can also contribute to inflammation. It can promote the destruction of important cell populations and trigger dramatic tissue remodeling following establishment of chronic disease. Therefore, a better understanding of TNF regulation is needed to allow pathogen control without causing or exacerbating disease. IL-10 is an important regulatory cytokine with broad activities, including the suppression of inflammation. IL-10 is produced by different immune cells; however, its regulation and function appears to be cell-specific and context-dependent. Recently, IL-10 produced by Th1 (Tr1 cells was shown to protect host tissues from inflammation induced following infection. Here, we identify a novel pathway of TNF regulation by IL-10 from Tr1 cells during parasitic infection. We report elevated Blimp-1 mRNA levels in CD4+ T cells from visceral leishmaniasis (VL patients, and demonstrate IL-12 was essential for Blimp-1 expression and Tr1 cell development in experimental VL. Critically, we show Blimp-1-dependent IL-10 production by Tr1 cells prevents tissue damage caused by IFNγ-dependent TNF production. Therefore, we identify Blimp-1-dependent IL-10 produced by Tr1 cells as a key regulator of TNF-mediated pathology and identify Tr1 cells as potential therapeutic tools to control inflammation.

  17. Synthesis and structural characterization of the Zintl phases Na{sub 3}Ca{sub 3}TrPn{sub 4}, Na{sub 3}Sr{sub 3}TrPn{sub 4}, and Na{sub 3}Eu{sub 3}TrPn{sub 4} (Tr=Al, Ga, In; Pn=P, As, Sb)

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yi [Department of Chemistry & Biochemistry, University of Delaware, 304A Drake Hall, Newark, DE 19716 (United States); Suen, Nian-Tzu [Department of Chemistry & Biochemistry, University of Delaware, 304A Drake Hall, Newark, DE 19716 (United States); College of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002 (China); Kunene, Thabiso; Stoyko, Stanislav [Department of Chemistry & Biochemistry, University of Delaware, 304A Drake Hall, Newark, DE 19716 (United States); Bobev, Svilen, E-mail: bobev@udel.edu [Department of Chemistry & Biochemistry, University of Delaware, 304A Drake Hall, Newark, DE 19716 (United States)

    2017-05-15

    15 new quaternary Zintl phases have been synthesized by solid-state reactions from the respective elements, and their structures have been determined by single-crystal X-ray diffraction. Na{sub 3}E{sub 3}TrPn{sub 4} (E=Ca, Sr, Eu; Tr=Al, Ga, In; Pn=P, As, Sb) crystallize in the hexagonal crystal system with the non-centrosymmetric space group P6{sub 3}mc (No. 186). The structure represents a variant of the K{sub 6}HgS{sub 4} structure type (Pearson index hP22) and features [TrPn{sub 4}]{sup 9–} tetrahedral units, surrounded by Na{sup +} and Ca{sup 2+}, Sr{sup 2+}, Eu{sup 2+} cations. The nominal formula rationalization [Na{sup +}]{sub 3}[E{sup 2+}]{sub 3}[TrPn{sub 4}]{sup 9–} follows the octet rule, suggesting closed-shell configurations for all atoms and intrinsic semiconducting behavior. However, structure refinements for several members hint at disorder and mixing of cations that potentially counteract the optimal valence electron count. - Graphical abstract: The hexagonal, non-centrosymmetric structure of Na{sub 3}E{sub 3}TrPn{sub 4} (E=Ca, Sr, Eu; Tr=Al, Ga, In; Pn=P, As, Sb) features [TrPn{sub 4}]{sup 9–} tetrahedral units, surrounded by Na{sup +} and Ca{sup 2+}, Sr{sup 2+}, Eu{sup 2+} cations. - Highlights: • 15 quaternary phosphides, arsenides, and antimonides are synthesized and structurally characterized. • The structure is a variant of the hexagonal K{sub 6}HgS{sub 4}-type, with distinctive pattern for the cations. • Occupational and/or positional disorder of yet unknown origin exists for some members of the series.

  18. Xylan oligosaccharides and cellobiohydrolase I (TrCel7A interaction and effect on activity

    Directory of Open Access Journals (Sweden)

    Baumann Martin J

    2011-10-01

    Full Text Available Abstract Background The well-studied cellulase mixture secreted by Trichoderma reesei (anamorph to Hypocrea jecorina contains two cellobiohydolases (CBHs, cellobiohydrolase I (TrCel7A and cellobiohydrolase II (TrCeI6A, that are core enzymes for the solubilisation of cellulose. This has attracted significant research interest because of the role of the CBHs in the conversion of biomass to fermentable sugars. However, the CHBs are notoriously slow and susceptible to inhibition, which presents a challenge for the commercial utilisation of biomass. The xylans and xylan fragments that are also present in the biomass have been suggested repeatedly as one cause of the reduced activity of CHBs. Yet, the extent and mechanisms of this inhibition remain poorly elucidated. Therefore, we studied xylan oligosaccharides (XOSs of variable lengths with respect to their binding and inhibition of both TrCel7A and an enzyme variant without the cellulose-binding domain (CBM. Results We studied the binding of XOSs to TrCel7A by isothermal titration calorimetry. We found that XOSs bind to TrCel7A and that the affinity increases commensurate with XOS length. The CBM, on the other hand, did not affect the affinity significantly, which suggests that XOSs may bind to the active site. Activity assays of TrCel7A clearly demonstrated the negative effect of the presence of XOSs on the turnover number. Conclusions On the basis of these binding data and a comparison of XOS inhibition of the activity of the two enzyme variants towards, respectively, soluble and insoluble substrates, we propose a competitive mechanism for XOS inhibition of TrCel7A with phosphoric swollen cellulose as a substrate.

  19. Utjecaj liberalizacije na tržište stočarskih proizvoda

    Directory of Open Access Journals (Sweden)

    Ružica Lončarić

    2004-01-01

    Full Text Available Ulaskom u Svjetsku trgovinsku organizaciju Republika Hrvatska je dokazala spremnost za izazove liberalizacije i globalizacije svjetskoga tržišta. Ovom je koraku prethodilo i potpisivanju drugih značajnih dokumenata za uključenje u europski integracijski proces, kao što je Pakt o stabilizaciji u istočnoj Europi, Sporazum o stabilizaciji i Pridruživanju EU i RH, službeno priključenje CEFTA-i, te službena prijava za članstvo u EU, koji na provođenje određenih reformi i prilagodbu u političkome, gospodarskom i pravnom smislu. Kako se hrvatska poljoprivreda, pogotovo grana stočarstva, od osamostaljenja i prihvaćanja tržišnog sustava gospodarenja, nalazi u velikoj krizi, u radu se analizira položaj stočarstva s obzirom na uvjete proizvodnje i brojno stanje stoke, tržište stočarskih proizvoda uz pomoć dinamičke raščlambe sustava proizvodnje stočarskih proizvoda, te se daju prognoze na koji će se način odvijati adaptacija stočarstva u uvjetima EU s obzirom na konkurentnost naših stočarskih proizvoda u europskom okruženju tes obzirom na liberalizacijske obveze. Rezultati analizirani u radu pokazuju kako je hrvatska proizvodnja i tržište stočarskih proizvoda u dubokoj krizi, te da bi bilo potrebno poduzeti niz tržišno-cjenovnih mjera agrarne politike koje bi uredilo navedeno tržište s obzirom na obveze i pravila o liberalizaciji trgovine unutar europskog tržišta.

  20. More on the TR-OSL signal from BeO ceramics

    International Nuclear Information System (INIS)

    Bulur, Enver

    2014-01-01

    Time Resolved Optically Stimulated Luminescence (TR-OSL) from BeO ceramics was investigated using blue (445 nm) and near-IR light (852 nm) for stimulation. Stimulation spectrum of the TR-OSL signal – as measured in the interval 700 to 420 nm- was observed to increase monotonically with the decreasing stimulation wavelength. In addition to the “fast” and “slow” components observed with blue light stimulation, IR stimulated TR-OSL spectra of irradiated BeO ceramics were observed to have two components with average lifetimes around ∼2.5 μs and ∼17 μs. Emission spectra of the both IR stimulated TR-OSL components were observed to have a broad emission band peaking around 330 nm. Thermal stability of the IR stimulated TR-OSL signal was studied by making preheating experiments in the range from 100 °C to 190 °C. It was observed that the IR stimulated OSL signal is stable up to ∼150 °C and decay afterwards. Radiation dose response of the IR stimulated luminescence signal was obtained in the range from 5 to 500 Gy. Both blue and IR stimulated TR-OSL signals grew up to 100 Gy and exhibited saturation for higher doses. Additionally, measurement temperature dependence of the components was also investigated and for the ∼2 μs component thermal assistance with activation energy around 0.16 eV was observed. It seems that the fast component of the blue stimulated TR-OSL component can be correlated to the ∼2 μs IR stimulated TR-OSL component. - Highlights: • IR Stimulated Time-Resolved OSL from BeO was studied. • Two components with lifetimes ∼2 and ∼17us were observed. • IR stimulated TR-OSL signal is found to be stable up to 150 °C. • Thermal quenching energy of the 2us component was found as 0.16 eV

  1. Transactivation of the proximal promoter of human oxytocin gene by TR4 orphan receptor

    International Nuclear Information System (INIS)

    Wang, C.-P.; Lee, Y.-F.; Chang, C.; Lee, H.-J.

    2006-01-01

    The human testicular receptor 4 (TR4) shares structural homology with members of the nuclear receptor superfamily. Some other members of this superfamily were able to regulate the transcriptional activity of the human oxytocin (OXT) promoter by binding to the first DR0 regulatory site. However, little investigation was conducted systematically in the study of the second dDR4 site of OXT proximal promoter, and the relationship between the first and the second sites of OXT promoter. Here, we demonstrated for the first time that TR4 could increase the proximal promoter activity of the human OXT gene via DR0, dDR4, and OXT (both DR0 and dDR4) elements, respectively. TR4 might induce OXT gene expression through the OXT element in a dose-dependent manner. However, there is no synergistic effect between DR0 and dDR4 elements during TR4 transactivation. Taken together, these results suggested that TR4 should be one of important regulators of OXT gene expression

  2. Reconstruction of sound source signal by analytical passive TR in the environment with airflow

    Science.gov (United States)

    Wei, Long; Li, Min; Yang, Debin; Niu, Feng; Zeng, Wu

    2017-03-01

    In the acoustic design of air vehicles, the time-domain signals of noise sources on the surface of air vehicles can serve as data support to reveal the noise source generation mechanism, analyze acoustic fatigue, and take measures for noise insulation and reduction. To rapidly reconstruct the time-domain sound source signals in an environment with flow, a method combining the analytical passive time reversal mirror (AP-TR) with a shear flow correction is proposed. In this method, the negative influence of flow on sound wave propagation is suppressed by the shear flow correction, obtaining the corrected acoustic propagation time delay and path. Those corrected time delay and path together with the microphone array signals are then submitted to the AP-TR, reconstructing more accurate sound source signals in the environment with airflow. As an analytical method, AP-TR offers a supplementary way in 3D space to reconstruct the signal of sound source in the environment with airflow instead of the numerical TR. Experiments on the reconstruction of the sound source signals of a pair of loud speakers are conducted in an anechoic wind tunnel with subsonic airflow to validate the effectiveness and priorities of the proposed method. Moreover the comparison by theorem and experiment result between the AP-TR and the time-domain beamforming in reconstructing the sound source signal is also discussed.

  3. Probiotic Bifidobacterium breve induces IL-10-producing Tr1 cells in the colon.

    Directory of Open Access Journals (Sweden)

    Seong Gyu Jeon

    Full Text Available Specific intestinal microbiota has been shown to induce Foxp3(+ regulatory T cell development. However, it remains unclear how development of another regulatory T cell subset, Tr1 cells, is regulated in the intestine. Here, we analyzed the role of two probiotic strains of intestinal bacteria, Lactobacillus casei and Bifidobacterium breve in T cell development in the intestine. B. breve, but not L. casei, induced development of IL-10-producing Tr1 cells that express cMaf, IL-21, and Ahr in the large intestine. Intestinal CD103(+ dendritic cells (DCs mediated B. breve-induced development of IL-10-producing T cells. CD103(+ DCs from Il10(-/-, Tlr2(-/-, and Myd88(-/- mice showed defective B. breve-induced Tr1 cell development. B. breve-treated CD103(+ DCs failed to induce IL-10 production from co-cultured Il27ra(-/- T cells. B. breve treatment of Tlr2(-/- mice did not increase IL-10-producing T cells in the colonic lamina propria. Thus, B. breve activates intestinal CD103(+ DCs to produce IL-10 and IL-27 via the TLR2/MyD88 pathway thereby inducing IL-10-producing Tr1 cells in the large intestine. Oral B. breve administration ameliorated colitis in immunocompromised mice given naïve CD4(+ T cells from wild-type mice, but not Il10(-/- mice. These findings demonstrate that B. breve prevents intestinal inflammation through the induction of intestinal IL-10-producing Tr1 cells.

  4. Probiotic Bifidobacterium breve induces IL-10-producing Tr1 cells in the colon.

    Science.gov (United States)

    Jeon, Seong Gyu; Kayama, Hisako; Ueda, Yoshiyasu; Takahashi, Takuya; Asahara, Takashi; Tsuji, Hirokazu; Tsuji, Noriko M; Kiyono, Hiroshi; Ma, Ji Su; Kusu, Takashi; Okumura, Ryu; Hara, Hiromitsu; Yoshida, Hiroki; Yamamoto, Masahiro; Nomoto, Koji; Takeda, Kiyoshi

    2012-01-01

    Specific intestinal microbiota has been shown to induce Foxp3(+) regulatory T cell development. However, it remains unclear how development of another regulatory T cell subset, Tr1 cells, is regulated in the intestine. Here, we analyzed the role of two probiotic strains of intestinal bacteria, Lactobacillus casei and Bifidobacterium breve in T cell development in the intestine. B. breve, but not L. casei, induced development of IL-10-producing Tr1 cells that express cMaf, IL-21, and Ahr in the large intestine. Intestinal CD103(+) dendritic cells (DCs) mediated B. breve-induced development of IL-10-producing T cells. CD103(+) DCs from Il10(-/-), Tlr2(-/-), and Myd88(-/-) mice showed defective B. breve-induced Tr1 cell development. B. breve-treated CD103(+) DCs failed to induce IL-10 production from co-cultured Il27ra(-/-) T cells. B. breve treatment of Tlr2(-/-) mice did not increase IL-10-producing T cells in the colonic lamina propria. Thus, B. breve activates intestinal CD103(+) DCs to produce IL-10 and IL-27 via the TLR2/MyD88 pathway thereby inducing IL-10-producing Tr1 cells in the large intestine. Oral B. breve administration ameliorated colitis in immunocompromised mice given naïve CD4(+) T cells from wild-type mice, but not Il10(-/-) mice. These findings demonstrate that B. breve prevents intestinal inflammation through the induction of intestinal IL-10-producing Tr1 cells.

  5. Nano-structured variable capacitor based on P(VDF-TrFE) copolymer and carbon nanotubes

    Science.gov (United States)

    Lakbita, I.; El-Hami, K.

    2018-02-01

    A newly organic capacitor was conceived with a variable capacitance using the inverse piezoelectric effect. The device consists of two parallel plates of carbon nanotubes (CNTs), known for their large surface area, high sensitivity and high electric conductivity, separated by a thin film of a dielectric layer of Polyinylidene fluoride and trifluoroehtylene (P(VDF-TrFE)) promising material for piezoelectric and ferroelectric properties. The obtained architecture is the CNT/PVDF-TrFE/CNT capacitor device. In this study, an ultra-thin film of P(VDF-TrFE) (54/46) with thickness of 20 nm was elaborated on highly oriented pyrolytic graphite (HOPG) by spin-coating. The morphology of the ultra-thin film and the mechanical behavior of CNT/P(VDF-TrFE)/CNT system were studied using the atomic force microscopy (AFM) combined with a lock-in amplifier in contact mode. All changes in applied voltage induce a change in thin film thickness according to the inverse piezoelectric effect that affect, consequently the capacitance. The results showed that the ratio of capacitance change ΔC to initial capacitance C0 is ΔC/C0=5%. This value is sufficient to use P(VDF-TrFE) as variable organic capacitor.

  6. Estimation of Theaflavins (TF) and Thearubigins (TR) Ratio in Black Tea Liquor Using Electronic Vision System

    Science.gov (United States)

    Akuli, Amitava; Pal, Abhra; Ghosh, Arunangshu; Bhattacharyya, Nabarun; Bandhopadhyya, Rajib; Tamuly, Pradip; Gogoi, Nagen

    2011-09-01

    Quality of black tea is generally assessed using organoleptic tests by professional tea tasters. They determine the quality of black tea based on its appearance (in dry condition and during liquor formation), aroma and taste. Variation in the above parameters is actually contributed by a number of chemical compounds like, Theaflavins (TF), Thearubigins (TR), Caffeine, Linalool, Geraniol etc. Among the above, TF and TR are the most important chemical compounds, which actually contribute to the formation of taste, colour and brightness in tea liquor. Estimation of TF and TR in black tea is generally done using a spectrophotometer instrument. But, the analysis technique undergoes a rigorous and time consuming effort for sample preparation; also the operation of costly spectrophotometer requires expert manpower. To overcome above problems an Electronic Vision System based on digital image processing technique has been developed. The system is faster, low cost, repeatable and can estimate the amount of TF and TR ratio for black tea liquor with accuracy. The data analysis is done using Principal Component Analysis (PCA), Multiple Linear Regression (MLR) and Multiple Discriminate Analysis (MDA). A correlation has been established between colour of tea liquor images and TF, TR ratio. This paper describes the newly developed E-Vision system, experimental methods, data analysis algorithms and finally, the performance of the E-Vision System as compared to the results of traditional spectrophotometer.

  7. Regulation of mitosis-meiosis transition by the ubiquitin ligase β-TrCP in male germ cells.

    Science.gov (United States)

    Nakagawa, Tadashi; Zhang, Teng; Kushi, Ryo; Nakano, Seiji; Endo, Takahiro; Nakagawa, Makiko; Yanagihara, Noriko; Zarkower, David; Nakayama, Keiko

    2017-11-15

    The mitosis-meiosis transition is essential for spermatogenesis. Specific and timely downregulation of the transcription factor DMRT1, and consequent induction of Stra8 expression, is required for this process in mammals, but the molecular mechanism has remained unclear. Here, we show that β-TrCP, the substrate recognition component of an E3 ubiquitin ligase complex, targets DMRT1 for degradation and thereby controls the mitosis-meiosis transition in mouse male germ cells. Conditional inactivation of β-TrCP2 in male germ cells of β-TrCP1 knockout mice resulted in sterility due to a lack of mature sperm. The β-TrCP-deficient male germ cells did not enter meiosis, but instead underwent apoptosis. The induction of Stra8 expression was also attenuated in association with the accumulation of DMRT1 at the Stra8 promoter in β-TrCP-deficient testes. DMRT1 contains a consensus β-TrCP degron sequence that was found to bind β-TrCP. Overexpression of β-TrCP induced the ubiquitylation and degradation of DMRT1. Heterozygous deletion of Dmrt1 in β-TrCP-deficient spermatogonia increased meiotic cells with a concomitant reduction of apoptosis. Collectively, our data indicate that β-TrCP regulates the transition from mitosis to meiosis in male germ cells by targeting DMRT1 for degradation. © 2017. Published by The Company of Biologists Ltd.

  8. Tráfico de drogas: uma opção entre escolhas escassas

    Directory of Open Access Journals (Sweden)

    Ana Amélia Cypreste Faria

    2011-12-01

    Full Text Available Este trabalho procura compreender os aspectos psicossociais que permeiam a adesão de pessoas ao tráfico de drogas em seu contexto histórico e econômico-social, por meio de pesquisa realizada no ambiente carcerário, onde foram recolhidas histórias de vida de pessoas envolvidas com o tráfico. Em um ambiente socioeconômico caracterizado pela precarização das relações de trabalho, pelo desemprego e pelo apelo consumista afinados com as premissas econômicas neoliberais tem-se uma situação de exclusão social e de cidadania. Assim, o tráfico se mostra como uma atividade econômica possibilitadora de inclusão, mesmo que marginal, na ordem capitalista. Uma opção a ser feita entre escolhas limitadas.

  9. Métodos de regulación de tráfico para redes urbanas

    OpenAIRE

    Canca Ortiz, José David

    1996-01-01

    En esta tesis se analiza el problema de la regulación de señales semafóricas en redes urbanas y su integración en un sistema de control del tráfico. La clasificación más habitual de los sistemas de control de tráfico se basa en la posibilidad de respuesta de los mismos frente a los continuos cambios en la evolución del comportamiento d el tráfico. Desde este punto de vista se pueden distinguir sistemas a tiempo fijo, semidinámicos y dinámicos (de segunda y tercera generación). El objetivo de ...

  10. Photometric investigation of hot exoplanets: TrES-3b and Qatar-1b

    Science.gov (United States)

    Püsküllü, Ç.; Soydugan, F.; Erdem, A.; Budding, E.

    2017-08-01

    New photometric follow-up observations of transitting 'hot Jupiters' TrES-3b and Qatar-1b are presented. Weighted mean values of the solutions of light curves in R-filter for both planetary systems are reported and compared with the previous results. The transit light curves were analysed using the WINFITTER code. The physical properties of the planets were estimated. The planet radii are found to be Rp = 1.381 ± 0.033RJ for TrES-3b and Rp = 1.142 ± 0.025RJ for Qatar-1b. Transit times and their uncertainties were also determined and a new linear ephemeris was computed for both systems. Analysis of transit times showed that a significant signal could not be determined for TrES-3b, while weak evidence was found for Qatar-1b, which might be tested using more precise future transit times.

  11. Inre och yttre motivation till träning : en kvalitativ studie bland regebundet aktiva kvinnor

    OpenAIRE

    Jonsson, Johanna

    2015-01-01

    Bakgrund: Regelbunden träning är viktig för både fysiskt och psykisktvälbefinnande. För att bibehålla en regelbundenhet i träningen krävs det ettengagemang och en motivation. En person kan motiveras av både inre ochyttre faktorer beroende på personens intresse. Trots att människor tenderaratt vara mer stillasittande, tycks intresset för träning och hälsa öka. Inteminst syns detta på sociala medier, där bilder och inlägg medträningsbudskap förmedlas frekvent. Syfte: Studiens syfte är att under...

  12. Luchas migrantes en contextos de tránsito migratorio, el caso del movimiento migrante centroamericano

    Directory of Open Access Journals (Sweden)

    Amarela Varela Huerta

    Full Text Available Resumen Este texto aborda un ejemplo concreto de organización de migrantes, el Movimiento Migrante Mesoamericano, que trabaja por los derechos de los migrantes en tránsito por México, de forma coordinada con organizaciones y familiares de migrantes víctimas de desaparición en su tránsito hacia Estados Unidos. Este estudio de caso es un ejemplo de luchas migrantes en contextos de tránsito, tipo específico de movimiento social que ha sido poco abordado en la literatura que piensa la acción colectiva de los migrantes. En el trabajo se analizan los actores, las prácticas, las alianzas y el contexto al que se enfrentan los activistas del movimiento en cuestión.

  13. Comparing Diagnostic Outcomes of Autism Spectrum Disorder Using DSM-IV-TR and DSM-5 Criteria.

    Science.gov (United States)

    Harstad, Elizabeth B; Fogler, Jason; Sideridis, Georgios; Weas, Sarah; Mauras, Carrie; Barbaresi, William J

    2015-05-01

    Controversy exists regarding the DSM-5 criteria for ASD. This study tested the psychometric properties of the DSM-5 model and determined how well it performed across different gender, IQ, and DSM-IV-TR sub-type, using clinically collected data on 227 subjects (median age = 3.95 years, majority had IQ > 70). DSM-5 was psychometrically superior to the DSM-IV-TR model (Comparative Fit Index of 0.970 vs 0.879, respectively). Measurement invariance revealed good model fit across gender and IQ. Younger children tended to meet fewer diagnostic criteria. Those with autistic disorder were more likely to meet social communication and repetitive behaviors criteria (p < .001) than those with PDD-NOS. DSM-5 is a robust model but will identify a different, albeit overlapping population of individuals compared to DSM-IV-TR.

  14. Building on TR-24 success. Advanced Cyclotron Systems Inc. launches a new cyclotron model

    International Nuclear Information System (INIS)

    Russell Watt; William Gyles; Alexander Zyuzin

    2015-01-01

    ACSI is designing a new 30 MeV cyclotron based on the TR-24. While minimizing changes from the proven TR-24, including maintaining the same outer dimensions, the energy of the cyclotron will be increased to 30 MeV, which will make it the most compact, non-superconducting, 30 MeV cyclotron design to date. Maximum beam current will match the TR-24 at 1 mA. With the size and footprint of a typical low energy PET cyclotron, this system will offer users a cost effective solution for a diversified facility capable of producing a wide spectrum of PET and SPECT radioisotopes for research and commercial distribution. (author)

  15. Leser-Trélat sign presenting in a patient with ovarian cancer: a case report

    Directory of Open Access Journals (Sweden)

    Bölke Edwin

    2009-07-01

    Full Text Available Abstract Introduction Seborrheic keratoses are very common findings in elderly patients. However, a sudden onset and dramatic increase in the number and size of these benign lesions deserves special attention, since this may represent the Leser Trélat sign, a rare paraneoplastic cutaneous syndrome. Case presentation A 92-year-old female presented to our clinic with multiple eruptive seborrheic keratoses, which had dramatically increased in size and number over the past two years. A diagnostic work-up revealed an ovarian carcinoma. Hence, cutaneous findings in our patient were consistent with the diagnosis of the Leser-Trélat sign. Conclusion The Leser-Trélat sign may coincide with the diagnosis of occult cancer or follow or precede it by months or years. Practitioners should take cases of eruptive seborrheic keratoses seriously and perform thorough patient examinations.

  16. Short TR imaging with refocusing of the steady-state transverse magnetization

    International Nuclear Information System (INIS)

    Zur, Y.; Stokar, S.; Bendel, P.

    1987-01-01

    Repetitive application of a sequence with repetition time (TR) shorter than T2 results in a steady state in which the transverse magnetization Mt reaches a nonzero value at the end of the sequence. This value depends on the TR and flip angle as well as on the frequency offset ν of each spin isochromat. The authors present a detailed analysis of the time domain and image domain signals for sequences with short TR that employ gradient reversal echoes. Because of the dependence of Mt on ν, two distinct echos appear in the time domain. With proper adjustment of the view gradients, each echo can be sampled separately. Image intensities derived for spins in a liquid (i.e., T1 -- T2) suggest enhanced signal intensity for the cerebrospinal fluid. This was confirmed experimentally

  17. Tempo e Trânsito na Experiência Subjetiva de Motoristas

    OpenAIRE

    Ana Inez Oka Elvas de Lima; Sylvia Cavalcante

    2015-01-01

    Esta pesquisa investiga como são percebidos e vivenciados o tempo e a pressa no trânsito por motoristas de Fortaleza, identificando e analisando seus estados subjetivos e comportamentos associados a essa experiência. Para a coleta de dados, organizaram-se quatro grupos focais, a partir dos quais emergiram diversos elementos relacionados ao tempo e à pressa e à incidência de comportamentos inadequados no trânsito, segundo o sexo e a idade dos participantes. Para analisar os dados obtidos nas d...

  18. Optimization Of PVDF-TrFE Processing Conditions For The Fabrication Of Organic MEMS Resonators.

    Science.gov (United States)

    Ducrot, Pierre-Henri; Dufour, Isabelle; Ayela, Cédric

    2016-01-21

    This paper reports a systematic optimization of processing conditions of PVDF-TrFE piezoelectric thin films, used as integrated transducers in organic MEMS resonators. Indeed, despite data on electromechanical properties of PVDF found in the literature, optimized processing conditions that lead to these properties remain only partially described. In this work, a rigorous optimization of parameters enabling state-of-the-art piezoelectric properties of PVDF-TrFE thin films has been performed via the evaluation of the actuation performance of MEMS resonators. Conditions such as annealing duration, poling field and poling duration have been optimized and repeatability of the process has been demonstrated.

  19. Space-charge-mediated anomalous ferroelectric switching in P(VDF-TrEE) polymer films

    KAUST Repository

    Hu, Weijin

    2014-11-12

    We report on the switching dynamics of P(VDF-TrEE) copolymer devices and the realization of additional substable ferroelectric states via modulation of the coupling between polarizations and space charges. The space-charge-limited current is revealed to be the dominant leakage mechanism in such organic ferroelectric devices, and electrostatic interactions due to space charges lead to the emergence of anomalous ferroelectric loops. The reliable control of ferroelectric switching in P(VDF-TrEE) copolymers opens doors toward engineering advanced organic memories with tailored switching characteristics.

  20. Posters y trípticos (Brochures) en LATEX con Beamer y Leaflet

    OpenAIRE

    Borbón, Alexánder

    2013-01-01

    Resumen. En este artículo se muestra la manera en que se puede realizar posters y trípticos (panfletos o brochures) con LATEX. Para realizar los posters se utiliza la clase beamer que usualmente se utiliza para hacer presentaciones, se utiliza el paquete beamerposter para poder utilizarla para posters. Los trípticos se realizan de dos formas, la primera utilizando la clase beamer con el paquete geometry y la segunda utilizando la clase leaflet que es una clase especializada para hacer este ti...

  1. Simultaneous spectral and photometric observations of the beat Cepheid U TrA

    International Nuclear Information System (INIS)

    Niva, G.D.; Schmidt, E.G.

    1981-01-01

    It was suggested that U TrA was a Cepheid with a modulated light curve. Further photometric and radial-velocity observations have confirmed this behaviour. Unfortunately, the radial velocities are too few in number and too scattered to allow a detailed analysis. This paper presents further photometric and spectroscopic observations of U TrA. The original intent was to obtain enough simultaneous observations to perform a Wesselink analysis similar to the one made for another beat Cepheid, TU Cas. Unfortunately, this has not been possible. However, the data obtained are of high quality and are clearly useful in studies of the modal content and period stability of the star. (author)

  2. Tráfico de drogas: uma opção entre escolhas escassas

    OpenAIRE

    Faria, Ana Amélia Cypreste; Barros, Vanessa de Andrade

    2011-01-01

    Este trabalho procura compreender os aspectos psicossociais que permeiam a adesão de pessoas ao tráfico de drogas em seu contexto histórico e econômico-social, por meio de pesquisa realizada no ambiente carcerário, onde foram recolhidas histórias de vida de pessoas envolvidas com o tráfico. Em um ambiente socioeconômico caracterizado pela precarização das relações de trabalho, pelo desemprego e pelo apelo consumista afinados com as premissas econômicas neoliberais tem-se uma situação de exclu...

  3. Mito & música: o trágico no jovem Nietzsche

    OpenAIRE

    Lotério, Rafael Antônio dos Santos

    2011-01-01

    O objetivo desta dissertação é perseguir o conceito de trágico na filosofia do jovem Friedrich Wilhelm Nietzsche. Através do estudo das suas primeiras obras dedicadas à reflexão filosófica, percebemos que a ideia do “trágico” se afirma como ponto central e ganha destaque para as perspectivas de trabalho vindouro para o professor de filologia clássica que se tornaria um dos mais importantes nomes da filosofia contemporânea. Entretanto, mesmo resguardando o valor que as reflexões...

  4. Rapid blockade of telomerase activity and tumor cell growth by the DPL lipofection of ribbon antisense to hTR.

    Science.gov (United States)

    Bajpai, Arun K; Park, Jeong-Hoh; Moon, Ik-Jae; Kang, Hyungu; Lee, Yun-Han; Doh, Kyung-Oh; Suh, Seong-Il; Chang, Byeong-Churl; Park, Jong-Gu

    2005-09-29

    Ribbon antisense (RiAS) to the hTR RNA, a component of the telomerase complex, was employed to inhibit telomerase activity and cancer cell growth. The antisense molecule, hTR-RiAS, combined with enhanced cellular uptake was shown to effectively inhibit telomerase activity and cause rapid cell death in various cancer cell lines. When cancer cells were treated with hTR-RiAS, the level of hTR RNA was reduced by more than 90% accompanied with reduction in telomerase activity. When checked for cancer cell viability, cancer cell lines treated with hTR-RiAS using DNA+Peptide+Lipid complex showed 70-80% growth inhibition in 3 days. The reduced cell viability was due to apoptosis as the percentage of cells exhibiting the sub-G0 arrest and DNA fragmentation increased after antisense treatment. Further, when subcutaneous tumors of a colon cancer cell line (SW480) were treated intratumorally with hTR-RiAS, tumor growth was markedly suppressed with almost total ablation of hTR RNA in the tumor tissue. Cells in the tumor tissue were also found to undergo apoptosis after hTR-RiAS treatment. These results suggest that hTR-RiAS is an effective anticancer reagent, with a potential for broad efficacy to diverse malignant tumors.

  5. Primerjalna analiza ključnih dejavnikov tržnega uspeha novih izdelkov v slovenskih predelovalnih panogah

    OpenAIRE

    Muster, Aleksandra

    2016-01-01

    Namen raziskave je bil na vzorcu podjetij slovenske predelovalne industrije ugotoviti, kako dejavniki kot so odzivna tržna naravnanost, organizacijsko učenje, proaktivna tržna naravnanost in inovativna organizacijska kultura vplivajo na tržni uspeh novih izdelkov ob pogojih uporabe sodobnih metod v okviru procesa razvoja novih izdelkov, tržnih in tehnoloških sprememb in uporabe zunanjih virov za inovacije v okviru procesa razvoja novih izdelkov. Večina ugotovitev iz empirične raziskave na ...

  6. A VDF/TrFE copolymer on silicon pyroelectric sensor: design considerations and experiments

    NARCIS (Netherlands)

    Setiadi, D.; Setiadi, D.; Regtien, Paulus P.L.

    1995-01-01

    For an optimal design of a VDF/TrFE (vinylidene fluoride trifluoroethylene) copolymer-on-silicon pyroelectric sensor, the one-dimensional diffusion equation is solved for the pyroelectric multilayer structure. Output current and voltage of the sensor are calculated. Improvement of the sensor can be

  7. Hans Georg Trüper (1936–2016 and His Contributions to Halophile Research

    Directory of Open Access Journals (Sweden)

    Aharon Oren

    2016-05-01

    Full Text Available Prof. Hans Georg Trüper, one of the most important scientists in the field of halophile research, passed away on 9 March 2016 at the age of 79. I here present a brief obituary with special emphasis on Prof. Trüper’s contributions to our understanding of the halophilic prokaryotes and their adaptations to life in hypersaline environments. He has pioneered the study of the halophilic anoxygenic phototrophic sulfur bacteria of the Ectothiorhodospira—Halorhodospira group. Some of the species he and his group isolated from hypersaline and haloalkaline environments have become model organisms for the study of the mechanisms of haloadaptation: the functions of three major organic compounds – glycine betaine, ectoine, and trehalose – known to serve as “compatible solutes” in halophilic members of the Bacteria domain, were discovered during studies of these anoxygenic phototrophs. Prof. Trüper’s studies of hypersaline alkaline environments in Egypt also led to the isolation of the first known extremely halophilic archaeon (Natronomonas pharaonis. The guest editors dedicate this special volume of Life to the memory of Prof. Hans Georg Trüper.

  8. Piezoelectricity enhancement of P(VDF/TrFE) by X-ray irradiation

    NARCIS (Netherlands)

    Pilet, N.; Khikhlovskyi, V.; van Breemen, A.J.J.M.; Michels, J.J.; Kemerink, M.; Gelinck, G.; Warnicke, P.; Bernard, L.

    2016-01-01

    Organic electronics is becoming more and more important because the low level of fabrication and deposition complexity even at large scale makes it a good candidate for future low cost technological product development. P(VDF-TrFE) is a co-polymer of special interest due its ferroelectric property

  9. TR146 cells grown on filters as a model of human buccal epithelium

    DEFF Research Database (Denmark)

    Nielsen, Hanne Mørck; Rassing, M R

    1999-01-01

    The aim of the present study was to evaluate the TR146 cell culture model as an in vitro model of human buccal epithelium with respect to the permeability enhancement by different pH values, different osmolality values or bile salts. For this purpose, the increase in the apparent permeability (P...

  10. Transport and Fatigue Properties of Ferroelectric Polymer P(VDF-TrFE) For Nonvolatile Memory Applications

    KAUST Repository

    Hanna, Amir

    2012-01-01

    injection and transport are believed to affect various properties of ferroelectric films such as remnant polarization values and polarization fatigue behavior.. Thus, this thesis aims to study charge injection in P(VDF-TrFE) and its transport properties as a

  11. Comparing personality disorder models: cross-method assessment of the FFM and DSM-IV-TR.

    Science.gov (United States)

    Samuel, Douglas B; Widiger, Thomas W

    2010-12-01

    The current edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR; American Psychiatric Association, 2000) defines personality disorders as categorical entities that are distinct from each other and from normal personality traits. However, many scientists now believe that personality disorders are best conceptualized using a dimensional model of traits that span normal and abnormal personality, such as the Five-Factor Model (FFM). However, if the FFM or any dimensional model is to be considered as a credible alternative to the current model, it must first demonstrate an increment in the validity of the assessment offered within a clinical setting. Thus, the current study extended previous research by comparing the convergent and discriminant validity of the current DSM-IV-TR model to the FFM across four assessment methodologies. Eighty-eight individuals receiving ongoing psychotherapy were assessed for the FFM and the DSM-IV-TR personality disorders using self-report, informant report, structured interview, and therapist ratings. The results indicated that the FFM had an appreciable advantage over the DSM-IV-TR in terms of discriminant validity and, at the domain level, convergent validity. Implications of the findings and directions for future research are discussed.

  12. Administrateur de la trésorerie (h/f) | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    examen annuel des procédures de gestion de la trésorerie et des processus de paiement;; Procéder au dépôt électronique de tous les documents constitutifs conformément aux normes applicables;; Préparer une analyse comptable périodique et ...

  13. Hvad er Erdogans næste træk i Syrien?

    DEFF Research Database (Denmark)

    Engen, Torben Toftgaard

    2017-01-01

    Hvad end Tyrkiets næste træk vil blive, kan det betyde forøgede flygtningestrømme fra Syrien til Danmark, bringe den internationale alliance mod IS i krise, vanskeliggøre samarbejdet i Nato og forværre det tyrkisk-amerikanske forhold....

  14. Leser–Trélat syndrome in malignant mesothelioma and pulmonary adenocarcinoma

    DEFF Research Database (Denmark)

    Jepsen, Rikke Karlin; Skov, Anne Guldhammer; Skov, Birgit Guldhammer

    2014-01-01

    The syndrome of Leser–Trélat (LT) is characterized by the sudden appearance of multiple seborrhoeic keratoses (SKs) in association with internal occult malignancy. Usually, the syndrome has been associated with adenocarcinoma, most frequently of the gastrointestinal tract and breast. The pathogen...

  15. Print Best jahib trükiteenuste turul liidrirolli / Toivo Tänavsuu

    Index Scriptorium Estoniae

    Tänavsuu, Toivo

    2004-01-01

    Konkursil Ettevõtluse auhind 2004 piirkonna edendaja nominentide hulka kuuluv Print Best on tõusnud viimase aastaga mahtudelt viie suurema poogentrükikoja hulka Eestis. Firma prioriteediks on Venemaa, mõeldud on müügiüksuse loomisele Moskvas. Lisa: Print Best Trükikoda

  16. Stratigraphie et structure de Trás-os-Montes oriental (Portugal)

    NARCIS (Netherlands)

    Ribeiro, Antonio; Almeida Rebelo, Jose

    1967-01-01

    Rocks in the eastern part of the province of Trás-os-Montes, N. Portugal belong to five units: 1: a complex of pre-Ordovician schists and greywackes; 2: Ordovician and Silurian sediments; 3: a low-grade metamorphic scries of Silurian age; 4: two complexes of probably Precambrian, predominantly meso-

  17. Comparing Diagnostic Outcomes of Autism Spectrum Disorder Using "DSM-IV-TR" and "DSM-5" Criteria

    Science.gov (United States)

    Harstad, Elizabeth B.; Fogler, Jason; Sideridis, Georgios; Weas, Sarah; Mauras, Carrie; Barbaresi, William J.

    2015-01-01

    Controversy exists regarding the "DSM-5" criteria for ASD. This study tested the psychometric properties of the "DSM-5" model and determined how well it performed across different gender, IQ, and "DSM-IV-TR" sub-type, using clinically collected data on 227 subjects (median age = 3.95 years, majority had IQ > 70).…

  18. Charakteristické rysy gotického románu a jejich vliv na tragický vývoj ženských hrdinek v díle Emily Brontëové Na Větrné Hůrce a Henryho Jamese Utažení šroubu

    OpenAIRE

    POSPÍCHALOVÁ, Kateřina

    2012-01-01

    The thesis ?Charakteristické rysy gotického románu a jejich vliv na tragický vývoj ženských hrdinek v díle Emily Brontëové Na Větrné hůrce a Henryho Jamese Utažení šroubu? is focused on heroines of these books and their fates and it analyzes elements of these books. The aim of the thesis is to specifficaly find and to analyze characteristic elements of gothic fiction in the books. The thesis is also focused on tragic development of the heroines, probable causes of their tragic fates and the c...

  19. Northrop Grumman TR202 LOX/LH2 Deep Throttling Engine Technology Project Status

    Science.gov (United States)

    Gromski, Jason; Majamaki, Annik; Chianese, Silvio; Weinstock, Vladimir; Kim, Tony S.

    2010-01-01

    NASA's Propulsion and Cryogenic Advanced Development (PCAD) project is currently developing enabling propulsion technologies in support of future lander missions. To meet lander requirements, several technical challenges need to be overcome, one of which is the ability for the descent engine(s) to operate over a deep throttle range with cryogenic propellants. To address this need, PCAD has enlisted Northrop Grumman Aerospace Systems (NGAS) in a technology development effort associated with the TR202 engine. The TR202 is a LOX/LH2 expander cycle engine driven by independent turbopump assemblies and featuring a variable area pintle injector similar to the injector used on the TR200 Apollo Lunar Module Descent Engine (LMDE). Since the Apollo missions, NGAS has continued to mature deep throttling pintle injector technology. The TR202 program has completed two series of pintle injector testing. The first series of testing used ablative thrust chambers and demonstrated igniter operation as well as stable performance at discrete points throughout the designed 10:1 throttle range. The second series was conducted with calorimeter chambers and demonstrated injector performance at discrete points throughout the throttle range as well as chamber heat flow adequate to power an expander cycle design across the throttle range. This paper provides an overview of the TR202 program, describing the different phases and key milestones. It describes how test data was correlated to the engine conceptual design. The test data obtained has created a valuable database for deep throttling cryogenic pintle technology, a technology that is readily scalable in thrust level.

  20. Assessment of lnternational Space Station (ISS) Lithium-ion Battery Thermal Runaway (TR)

    Science.gov (United States)

    Graika, Jason

    2017-01-01

    This task was developed in the wake of the Boeing 787 Dreamliner lithium-ion battery TR incidents of January 2013 and January 2014. The Electrical Power Technical Discipline Team supported the Dreamliner investigations and has followed up by applying lessons learned to conduct an introspective evaluation of NASA's risk of similar incidents in its own lithium-ion battery deployments. This activity has demonstrated that historically NASA, like Boeing and others in the aerospace industry, has emphasized the prevention of TR in a single cell within the battery (e.g., cell screening) but has not considered TR severity-reducing measures in the event of a single-cell TR event. center dotIn the recent update of the battery safety standard (JSC 20793) to address this paradigm shift, the NASA community included requirements for assessing TR severity and identifying simple, low-cost severity reduction measures. This task will serve as a pathfinder for meeting those requirements and will specifically look at a number of different lithium-ion batteries currently in the design pipeline within the ISS Program batteries that, should they fail in a Dreamliner-like incident, could result in catastrophic consequences. This test is an abuse test to understand the heat transfer properties of the cell and ORU in thermal runaway, with radiant barriers in place in a flight like test in on orbit conditions. This includes studying the heat flow and distribution in the ORU. This data will be used to validate the thermal runaway analysis. This test does not cover the ambient pressure case. center dotThere is no pass/ fail criteria for this test.

  1. The Traffic Adaptive Data Dissemination (TrAD Protocol for both Urban and Highway Scenarios

    Directory of Open Access Journals (Sweden)

    Bin Tian

    2016-06-01

    Full Text Available The worldwide economic cost of road crashes and injuries is estimated to be US$518 billion per year and the annual congestion cost in France is estimated to be €5.9 billion. Vehicular Ad hoc Networks (VANETs are one solution to improve transport features such as traffic safety, traffic jam and infotainment on wheels, where a great number of event-driven messages need to be disseminated in a timely way in a region of interest. In comparison with traditional wireless networks, VANETs have to consider the highly dynamic network topology and lossy links due to node mobility. Inter-Vehicle Communication (IVC protocols are the keystone of VANETs. According to our survey, most of the proposed IVC protocols focus on either highway or urban scenarios, but not on both. Furthermore, too few protocols, considering both scenarios, can achieve high performance. In this paper, an infrastructure-less Traffic Adaptive data Dissemination (TrAD protocol which takes into account road traffic and network traffic status for both highway and urban scenarios will be presented. TrAD has double broadcast suppression techniques and is designed to adapt efficiently to the irregular road topology. The performance of the TrAD protocol was evaluated quantitatively by means of realistic simulations taking into account different real road maps, traffic routes and vehicular densities. The obtained simulation results show that TrAD is more efficient in terms of packet delivery ratio, number of transmissions and delay in comparison with the performance of three well-known reference protocols. Moreover, TrAD can also tolerate a reasonable degree of GPS drift and still achieve efficient data dissemination.

  2. The Traffic Adaptive Data Dissemination (TrAD) Protocol for both Urban and Highway Scenarios.

    Science.gov (United States)

    Tian, Bin; Hou, Kun Mean; Zhou, Haiying

    2016-06-21

    The worldwide economic cost of road crashes and injuries is estimated to be US$518 billion per year and the annual congestion cost in France is estimated to be €5.9 billion. Vehicular Ad hoc Networks (VANETs) are one solution to improve transport features such as traffic safety, traffic jam and infotainment on wheels, where a great number of event-driven messages need to be disseminated in a timely way in a region of interest. In comparison with traditional wireless networks, VANETs have to consider the highly dynamic network topology and lossy links due to node mobility. Inter-Vehicle Communication (IVC) protocols are the keystone of VANETs. According to our survey, most of the proposed IVC protocols focus on either highway or urban scenarios, but not on both. Furthermore, too few protocols, considering both scenarios, can achieve high performance. In this paper, an infrastructure-less Traffic Adaptive data Dissemination (TrAD) protocol which takes into account road traffic and network traffic status for both highway and urban scenarios will be presented. TrAD has double broadcast suppression techniques and is designed to adapt efficiently to the irregular road topology. The performance of the TrAD protocol was evaluated quantitatively by means of realistic simulations taking into account different real road maps, traffic routes and vehicular densities. The obtained simulation results show that TrAD is more efficient in terms of packet delivery ratio, number of transmissions and delay in comparison with the performance of three well-known reference protocols. Moreover, TrAD can also tolerate a reasonable degree of GPS drift and still achieve efficient data dissemination.

  3. Tidlig struktureret mobilisering og træning af kritisk syge patienter på et dansk intensivafsnit

    DEFF Research Database (Denmark)

    Astrup Sørensen, Katrine; Hvid, Sidsel; Rolving, Nanna

    2015-01-01

    derimod anvendelig i forhold til at tilpasse niveauet for mobilisering og træning. Relevans for klinisk praksis: Tidlig mobilisering og træning er mulig at indføre med en simpel algoritme, dog med hensyntagen til individuelle screeningskriterier fra sted til sted, da disse åbenbart ikke er nemme...

  4. Autism Spectrum Disorders According to "DSM-IV-TR" and Comparison with "DSM-5" Draft Criteria: An Epidemiological Study

    Science.gov (United States)

    Mattila, Marja-Leena; Kielinen, Marko; Linna, Sirkka-Liisa; Jussila, Katja; Ebeling, Hanna; Bloigu, Risto; Joseph, Robert M.; Moilanen, Irma

    2011-01-01

    Objective: The latest definitions of autism spectrum disorders (ASDs) were specified in "DSM-IV-TR" in 2000. "DSM-5" criteria are planned for 2013. Here, we estimated the prevalence of ASDs and autism according to "DSM-IV-TR," clarified confusion concerning diagnostic criteria, and evaluated "DSM-5" draft…

  5. Transport and Fatigue Properties of Ferroelectric Polymer P(VDF-TrFE) For Nonvolatile Memory Applications

    KAUST Repository

    Hanna, Amir

    2012-06-01

    Organic ferroelectrics polymers have recently received much interest for use in nonvolatile memory devices. The ferroelectric copolymer poly(vinylidene fluoride- trifluoroethylene) , P(VDF-TrFE), is a promising candidate due to its relatively high remnant polarization, low coercive field, fast switching times, easy processability, and low Curie transition. However, no detailed study of charge injection and current transport properties in P(VDF-TrFE) have been reported in the literature yet. Charge injection and transport are believed to affect various properties of ferroelectric films such as remnant polarization values and polarization fatigue behavior.. Thus, this thesis aims to study charge injection in P(VDF-TrFE) and its transport properties as a function of electrode material. Injection was studied for Al, Ag, Au and Pt electrodes. Higher work function metals such as Pt have shown less leakage current compared to lower work function metals such as Al for more than an order of magnitude. That implied n-type conduction behavior for P(VDF-TrFE), as well as electrons being the dominant injected carrier type. Charge transport was also studied as a function of temperature, and two major transport regimes were identified: 1) Thermionic emission over a Schottky barrier for low fields (E < 25 MV/m). 2) Space-Charge-Limited regime at higher fields (25 < E <120 MV/m). We have also studied the optical imprint phenomenon, the polarization fatigue resulting from a combination of broad band optical illumination and DC bias near the switching field. A setup was designed for the experiment, and validated by reproducing the reported effect in polycrystalline Pb(Zr,Ti)O3 , PZT, film. On the other hand, P(VDF-TrFE) film showed no polarization fatigue as a result of optical imprint test, which could be attributed to the large band gap of the material, and the low intensity of the UV portion of the arc lamp white light used for the experiment. Results suggest using high work

  6. Factores tróficos en neuronas dopaminérgicas mesencefálicas

    Directory of Open Access Journals (Sweden)

    G. Pinzón

    1994-12-01

    Full Text Available Desde su descubrimiento, se ha postulado, y en algunos casos comprobado, que los factores tróficos juegan un papel importante en el desarrollo, mantenimiento y regeneración del sistema nervioso. El conocimiento y la manipulación de estas sustancias ha servido para: a formular nuevas teorías acerca de la etiología de varios desórdenes neurodebeneraivos y b desarrollar nuevas altemativas terapéuticas para estas entidades. En la presente revisión, resumimos los principales efectos de diferentes factores tróficos sobre las neuronas dopaminérgicas de la substantia nigra en desarrollo, cuya degeneración en el adulto ocasiona la mayoría de los síntomas observados en la enfermedad de Parkinson.

  7. Porto de Trás: etnicidade, turismo e patrimonialização

    Directory of Open Access Journals (Sweden)

    Patrícia de Araújo Brandão Couto

    2011-05-01

    Full Text Available The article describes the process by which cultural heritage of Porto de Trás, a neigborhood in Itacaré on the southern coast of Bahia, Brazil, has gained recognition. Porto de Trás is an ethnic community of African Brazilians with a tradition of artisanal fishing. Historically, its residents, organized in family groupings, have been segregated for their race and socioeconomic status.Even with the arrival of the tourist industry in the 1990s and concomitant urban developments, it maintained its traditional cultural practices, gaining recognition as an enclave of “authenticity” referred to local culture. Interactions between the different spheres of heritage operating in this space are discussed especially the construction of ethnicity by local residents.

  8. Porto\tde Trás: etnicidade, turismo e patrimonialização

    Directory of Open Access Journals (Sweden)

    Patrícia de Araújo Brandão Couto

    2011-01-01

    Full Text Available The article describes the process by which cultural heritage of Porto de Trás, a neigborhood in Itacaré on the southern coast of Bahia, Brazil, has gained recognition. Porto de Trás is an ethnic community of African Brazilians with a tradition of artisanal fishing. Historically, its residents, organized in family groupings, have been segregated for their race and socioeconomic status. Even with the arrival of the tourist industry in the 1990s and concomitant urban developments, it maintained its traditional cultural practices, gaining recognition as an enclave of "authenticity" referred to local culture. Interactions between the different spheres of heritage operating in this space are discussed especially the construction of ethnicity by local residents

  9. AN EFFICIENT DATA MINING METHOD TO FIND FREQUENT ITEM SETS IN LARGE DATABASE USING TR- FCTM

    Directory of Open Access Journals (Sweden)

    Saravanan Suba

    2016-01-01

    Full Text Available Mining association rules in large database is one of most popular data mining techniques for business decision makers. Discovering frequent item set is the core process in association rule mining. Numerous algorithms are available in the literature to find frequent patterns. Apriori and FP-tree are the most common methods for finding frequent items. Apriori finds significant frequent items using candidate generation with more number of data base scans. FP-tree uses two database scans to find significant frequent items without using candidate generation. This proposed TR-FCTM (Transaction Reduction- Frequency Count Table Method discovers significant frequent items by generating full candidates once to form frequency count table with one database scan. Experimental results of TR-FCTM shows that this algorithm outperforms than Apriori and FP-tree.

  10. RNA-Seq-Based Transcript Structure Analysis with TrBorderExt.

    Science.gov (United States)

    Wang, Yejun; Sun, Ming-An; White, Aaron P

    2018-01-01

    RNA-Seq has become a routine strategy for genome-wide gene expression comparisons in bacteria. Despite lower resolution in transcript border parsing compared with dRNA-Seq, TSS-EMOTE, Cappable-seq, Term-seq, and others, directional RNA-Seq still illustrates its advantages: low cost, quantification and transcript border analysis with a medium resolution (±10-20 nt). To facilitate mining of directional RNA-Seq datasets especially with respect to transcript structure analysis, we developed a tool, TrBorderExt, which can parse transcript start sites and termination sites accurately in bacteria. A detailed protocol is described in this chapter for how to use the software package step by step to identify bacterial transcript borders from raw RNA-Seq data. The package was developed with Perl and R programming languages, and is accessible freely through the website: http://www.szu-bioinf.org/TrBorderExt .

  11. Síndrome de Isaacs: relato de três casos

    Directory of Open Access Journals (Sweden)

    SCOLA ROSANA HERMÍNIA

    1999-01-01

    Full Text Available Relatamos três casos de síndrome de Isaacs, que apresentavam mioquímia clínica, cãibras, dificuldades para o relaxamento muscular, hipertrofia muscular e aumento da sudorese. A eletromiografia de agulha mostrou atividade muscular contínua involuntária, caracterizada como descargas mioquímicas. Os estudos da condução nervosa foram normais. Biópsia de músculo, realizado nos três casos, mostrou atrofia de fibras do tipo 2. Dois casos apresentaram melhora clínica com a utilização de carbamazepina e um com prednisona.

  12. A review of the probabilistic safety assessment application to the TR-2 research reactor

    International Nuclear Information System (INIS)

    Goektepe, G.; Adalioglu, U.; Anac, H.; Sevdik, B.; Menteseoglu, S.

    2001-01-01

    A review of the Probabilistic Safety Assessment (PSA) to the TR-2 Research Reactor is presented. The level 1 PSA application involved: selection of accident initiators, mitigating functions and system definitions, event tree constructions and quantification, fault tree constructions and quantification, human reliability, component failure data base development, dependent failure analysis. Each of the steps of the analysis given above is reviewed briefly with highlights from the selected results. PSA application is found to be a practical tool for research reactor safety due to intense involvement of human interactions in an experimental facility. Insights gained from the application of PSA methodology to the TR-2 research reactor led to a significant safety review of the system

  13. Advanced Packaging Materials and Techniques for High Power TR Module: Standard Flight vs. Advanced Packaging

    Science.gov (United States)

    Hoffman, James Patrick; Del Castillo, Linda; Miller, Jennifer; Jenabi, Masud; Hunter, Donald; Birur, Gajanana

    2011-01-01

    The higher output power densities required of modern radar architectures, such as the proposed DESDynI [Deformation, Ecosystem Structure, and Dynamics of Ice] SAR [Synthetic Aperture Radar] Instrument (or DSI) require increasingly dense high power electronics. To enable these higher power densities, while maintaining or even improving hardware reliability, requires advances in integrating advanced thermal packaging technologies into radar transmit/receive (TR) modules. New materials and techniques have been studied and compared to standard technologies.

  14. Detection of Planetary Emission from the Exoplanet TrES-2 Using Spitzer/IRAC

    Science.gov (United States)

    Donovan, Francis T.; Charbonneau, David; Harrington, Joseph; Madhusudhan, N.; Seager, Sara; Deming, Drake; Knutson, Heather A.

    2010-01-01

    We present here the results of our observations of TrES-2 using the Infrared Array Camera on Spitzer. We monitored this transiting system during two secondary eclipses, when the planetary emission is blocked by the star. The resulting decrease in flux is 0.127% +/- 0.021%, 0.230% +/- 0.024%, 0.199% +/- 0.054%, and 0.359% +/- 0.060% at 3.6 microns, 4.5 microns, 5.8 microns, and 8.0 microns, respectively. We show that three of these flux contrasts are well fit by a blackbody spectrum with T(sub eff) = 1500 K, as well as by a more detailed model spectrum of a planetary atmosphere. The observed planet-to-star flux ratios in all four lRAC channels can be explained by models with and without a thermal inversion in the atmosphere of TrES-2, although with different atmospheric chemistry. Based on the assumption of thermochemical equilibrium, the chemical composition of the inversion model seems more plausible, making it a more favorable scenario. TrES-2 also falls in the category of highly irradiated planets which have been theoretically predicted to exhibit thermal inversions. However, more observations at infrared and visible wavelengths would be needed to confirm a thermal inversion in this system. Furthermore, we find that the times of the secondary eclipses are consistent with previously published times of transit and the expectation from a circular orbit. This implies that TrES-2 most likely has a circular orbit, and thus does not obtain additional thermal energy from tidal dissipation of a non-zero orbital eccentricity, a proposed explanation for the large radius of this planet. Key words: eclipses - infrared: stars - planetary systems - stars: individual (OSC 03549-02811) - techniques: photometric

  15. La socialisation sexospécifique des très jeunes adolescents à l ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Les adolescents de l'Afrique subsaharienne, en particulier ceux issus de zones urbaines à faible revenu, sont très vulnérables en ce qui concerne la santé sexuelle et reproductive. La plupart des interventions visant à améliorer la santé sexuelle et reproductive des adolescents sont axées sur les adolescents plus âgés et ...

  16. Morphdynamics of Beaches in the Tróia-Sines Littoral Ribbon (SW Portugal)

    OpenAIRE

    Gama, Cristina; Andrade, César; Taborda, Rui; Freitas, Conceição

    2006-01-01

    In the Tróia-Sines littoral ribbon five beaches were monitored in order to evaluate morphological and textural changes. The textural analysis reveals a southward coarsening trend that reflects an increase in the wave energy. The morphodynamic data indicate that the modal stages are intermediate to reflective, and that the available beach volume increases southwards. During storm periods the volumetric changes reach 15% to 82% of the beach envelope corresponding to magnitudes of 6x10 3 to 2x10...

  17. ¿Puede la música expresar lo trágico?

    Directory of Open Access Journals (Sweden)

    Enrico Fubini

    2013-12-01

    Full Text Available [ES] Este trabajo parte de la pregunta sobre si el arte musical es capaz de expresar realmente el sentimiento trágico, e intenta clarificar la relación que existe (si existe entre el concepto de lo trágico y el lenguaje de la música. En concreto, se trata de reconstruir la historia de esta relación empezando por sus raíces, hundidas en la tragedia griega, para llegar a sus más cercanas expresiones en el siglo XX. Se pone el acento en el valor trágico del propio contenido musical, destacando con atención, en el caso del melodrama, la relación que surge entre una emoción expresada en palabras y aquella que nace de la música misma, así como la contradicción aparente entre la belleza de la armonía de la música polifónica con el sentimiento de lo verdaderamente trágico. ; [EN] This writing raises the question if the musical art is able to really express the feeling of the tragic, and tries to clarify the relation that exist (if it exists between the concept of the tragic and the language of music. In particular, it aims to reconstruct the history of this relation beginning by its roots, sunk in Greek tragedy, to arrive at its nearer expressions in the XX century. The accent is on the tragic value of the musical content itself, emphasizing in particular, in the case of the melodrama, the relation that arise between an emotion expressed in words and that that is born of music itself, as well as the apparent contradiction between the beauty of the harmony of polyphonic music and the feeling of the truly tragic.

  18. Tržna analiza in razvoj aluminijastih ohišij LED svetil

    OpenAIRE

    Gorišek, Krešimir

    2014-01-01

    V magistrskem delu je predstavljena tržna analiza oziroma natančneje analiza zunanjega okolja organizacije. Privlačnost panoge smo ocenjevali s Porterjevim modelom konkurence v panogi in ugotovitve predstavili. Analizo širšega zunanjega okolja oziroma analizo političnih, ekonomskih, socialnih, tehnoloških, okoljskih in pravnih elementov smo izvedli s PESTEL analizo in ugotovitve predstavili. Magistrsko delo obsega tudi razvoj aluminijastih ohišij LED (Light Emitting Diode) svetil. Podrobneje ...

  19. Sensitivity of diamond-capped impedance transducer to Tröger’s base derivatives

    Czech Academy of Sciences Publication Activity Database

    Stehlík, Štěpán; Ižák, Tibor; Kromka, Alexander; Dolenský, B.; Havlík, M.; Rezek, Bohuslav

    2012-01-01

    Roč. 4, č. 8 (2012), s. 3860-3865 ISSN 1944-8244 R&D Projects: GA ČR(CZ) GBP108/12/G108 Institutional research plan: CEZ:AV0Z10100521 Keywords : Tröger’s base derivative * nanocrystalline diamond * chemical sensor * impedance spectroscopy * surface conductivity Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 5.008, year: 2012

  20. Diagnostic Distribution of eating disorders: Comparison between DSMIV- TR and DSM-5.

    Science.gov (United States)

    Serrano-Troncoso, Eduardo; Cañas, Laura; Carbonell, Xavier; Carulla, Marta; Palma, Carolina; Matalí, Josep; Dolz, Montse

    2017-01-01

    The fifth edition of Diagnostic and Statistical Manual of Mental Disorders (DSM-5) includes a significant revision of Eating Disorders (ED). The objective of this study is to compare the distribution of diagnosis of ED in adolescents according to DSM-VI-TR and DSM-5 criteria. A second objective is to study the psychopathological differences between patients with ED (based on DSM-IV-TR) and those whose diagnosis changed by applying DSM-5 criteria. One hundred and one adolescents diagnosed with ED (mean: 14.68 years; SD: 1.46) were evaluated with clinical interviews and scales for eating psychopathology, perfectionism, anxiety, and depression. Applying the DSM-5 criteria led to a significant decrease in the diagnosed cases of Eating Disorders Not Otherwise Specified (EDNOS) (from 34.7% to 23.8%; p<0.001) and to a significant increase in those of anorexia nervosa (AN) (from 58.4% to 66.3%; p<0.001) and of bulimia nervosa (BN) (from 6.9% to 8.9%; p<0.001). No significant psychopathological differences were found between patients diagnosed with AN and BN based on DSM-IV-TR criteria and those newly diagnosed with AN and BN based on DSM-5 criteria. Using DSM-5 criteria for adolescents with ED leads to a significant decrease in the frequency of an EDNOS diagnosis. As similar psychopathological characteristics were observed between ED patients diagnosed based on DSM-IV-TR and those who were switched from EDNOS to AN or BN based on DSM-5, we conclude that the new criteria for ED in DSM-5 are valid for an adolescent population.

  1. Tempo e Trânsito na Experiência Subjetiva de Motoristas

    Directory of Open Access Journals (Sweden)

    Ana Inez Oka Elvas de Lima

    2015-03-01

    Full Text Available Esta pesquisa investiga como são percebidos e vivenciados o tempo e a pressa no trânsito por motoristas de Fortaleza, identificando e analisando seus estados subjetivos e comportamentos associados a essa experiência. Para a coleta de dados, organizaram-se quatro grupos focais, a partir dos quais emergiram diversos elementos relacionados ao tempo e à pressa e à incidência de comportamentos inadequados no trânsito, segundo o sexo e a idade dos participantes. Para analisar os dados obtidos nas discussões grupais utilizaram-se os critérios da Análise Clássica de Conteúdo. Os resultados levaram à conclusão de que a questão do tempo e da pressa constitui um potencial gerador de erros e violações na condução de veículos, pois exerce influência decisiva sobre os comportamentos dos motoristas e configura uma realidade importante para se compreender os fatores humanos envolvidos na dinâmica do trânsito e do ambiente urbano como um todo.

  2. Status and results from the TR30 cyclotron centre region model

    International Nuclear Information System (INIS)

    Kleeven, W.; Lanz, P.; McDonald, M.; Milton, B.F.; Schmor, P.W.; Schneider, H.R.; Jayamanna, K.; Sura, J.; Uzat, W.; Gyles, W.

    1990-06-01

    A full scale model for the centre region of the compact 30 MeV, 350 μA H - cyclotron (TR30) has been constructed, to test the design of critical components and to study beam properties and space charge effects out to the 5. turn (1 MeV). The ion source and injection line system duplicates that used in the TR30. The centre region can be accessed with diagnostic probes at four different angles. The normalized circulating emittances as estimated from beam profile measurements are 1.7π mm-mrad (radially) and 1.8π mm-mrad (vertically). The radial centering error of the beam is less than 1.5 mm. After initial tests the maximum intensity achieved at the 5. turn is 650 μA. This corresponds with a transmission efficiency of 12.5% for a continuous (non-bunched) input beam. No significant space charge effects are observed up to 650 μA. For the TR30 bunching is not a must because of the high current available from the source. Nevertheless, it was considered useful to study beam bunching for the Centre Region Cyclotron (CRC). Some of these results are described. (Author) 11 refs., 6 figs

  3. Mortalidad por accidentes de tránsito en Bayamo, Cuba 2011

    Directory of Open Access Journals (Sweden)

    Arlines Piña-Tornés

    Full Text Available Con el objetivo de describir la mortalidad por accidentes de tránsito en Bayamo, Cuba, en el año 2011 se realizó una revisión de los pacientes lesionados y fallecidos a causa de accidentes de tránsito, registrados en Hospital Carlos M. de Céspedes. Se atendieron en emergencias 1365 lesionados, predominando el grupo etario de 25 a 44 años con 372 pacientes (27,3%, y el sexo masculino con 1071 (78,5%. Fallecieron 46 personas, en su mayoría del mismo grupo de edad y de sexo masculino. Los traumatismos múltiples (52,6% y cráneofaciales (34,2% fueron las localizaciones predominantes. Se destacaron los atropellos por vehículo de motor con mortalidad del 26,3%. En conclusión, la mortalidad por accidentes de tránsito predomina en adultos jóvenes masculinos; cuyas consecuencias fatales son debido a traumatismos múltiples por atropellos.

  4. Nicotine permeability across the buccal TR146 cell culture model and porcine buccal mucosa in vitro

    DEFF Research Database (Denmark)

    Nielsen, Hanne Mørck; Rassing, Margrethe Rømer

    2002-01-01

    The present study was conducted to investigate and compare the effect of pH and drug concentration on nicotine permeability across the TR146 cell culture model and porcine buccal mucosa in vitro. As a further characterization of the TR146 cell culture model, it was explored whether the results were...... comparable for bi-directional and uni-directional transport in the presence of a transmembrane pH gradient. Nicotine concentrations between 10(-5) and 10(-2) M were applied to the apical side of the TR146 cell culture model or the mucosal side of porcine buccal mucosa. Buffers with pH values of 5.5, 7.......4 and 8.1 were used to obtain different fractions of non- and mono-ionized nicotine. The apparent permeability (P(app)) of nicotine across both models increased significantly with increasing pH, and the P(app) values obtained with the two models could be correlated in a linear manner. With increasing...

  5. Organisation and standardisation of information in SWISS-PROT and TrEMBL

    Directory of Open Access Journals (Sweden)

    Michele Magrane

    2006-01-01

    Full Text Available SWISS-PROT is a curated, non-redundant protein sequence database which provides a high level of annotation and is integrated with a large number of other biological databases. It is supplemented by TrEMBL, a computer-annotated database which contains translations of all coding sequences in the EMBL Nucleotide Sequence Database which are not yet in SWISS-PROT. Each fully curated SWISS-PROT entry contains as much up-to-date information as possible from a variety of sources and the high quality of the annotation in SWISS-PROT provides the basis for the procedure which is used to automatically annotate the TrEMBL database. The large amounts of different data types found in both databases are stored in a highly structured and uniform manner and this structured organisation means that SWISS-PROT and TrEMBL together provide a comprehensive resource with data that are readily accessible for users and easily retrievable by computer programs.

  6. Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway.

    Science.gov (United States)

    Wang, Wei-jia; Wang, Yuan; Chen, Hang-zi; Xing, Yong-zhen; Li, Feng-wei; Zhang, Qian; Zhou, Bo; Zhang, Hong-kui; Zhang, Jie; Bian, Xue-li; Li, Li; Liu, Yuan; Zhao, Bi-xing; Chen, Yan; Wu, Rong; Li, An-zhong; Yao, Lu-ming; Chen, Ping; Zhang, Yi; Tian, Xu-yang; Beermann, Friedrich; Wu, Mian; Han, Jiahuai; Huang, Pei-qiang; Lin, Tianwei; Wu, Qiao

    2014-02-01

    Autophagy is linked to cell death, yet the associated mechanisms are largely undercharacterized. We discovered that melanoma, which is generally resistant to drug-induced apoptosis, can undergo autophagic cell death with the participation of orphan nuclear receptor TR3. A sequence of molecular events leading to cellular demise is launched by a specific chemical compound, 1-(3,4,5-trihydroxyphenyl)nonan-1-one, newly acquired from screening a library of TR3-targeting compounds. The autophagic cascade comprises TR3 translocation to mitochondria through interaction with the mitochondrial outer membrane protein Nix, crossing into the mitochondrial inner membrane through Tom40 and Tom70 channel proteins, dissipation of mitochondrial membrane potential by the permeability transition pore complex ANT1-VDAC1 and induction of autophagy. This process leads to excessive mitochondria clearance and irreversible cell death. It implicates a new approach to melanoma therapy through activation of a mitochondrial signaling pathway that integrates a nuclear receptor with autophagy for cell death.

  7. Control de tráfico vehicular usando ANFIS Vehicular traffic control using ANFIS

    Directory of Open Access Journals (Sweden)

    Luis Fernando Pedraza

    2012-04-01

    Full Text Available Diferentes estrategias para el control del tráfico urbano se han presentado a lo largo del tiempo. Este artículo presenta el diseño de un modelo de tráfico vehicular, el cual examina el tráfico existente en una vía a través de una serie de semáforos. A partir de este modelo se sincronizan los tiempos de duración y de desfase de los semáforos, utilizando para ello el Sistema de Inferencia Difusa Basado en Redes Adaptativas (ANFIS. El modelo es simulado y los resultados se evalúan a nivel macroscópico con el modelo de tiempos fijos, que funciona actualmente en Bogotá-Colombia.Different strategies for urban traffic control have been presented over time. This paper presents the design of a vehicular traffic model, examining the existing traffic through a serie of traffic lights on a road. From this model the times of duration and phase of the traffic lights are synchronized, using the Adaptive Network Based Fuzzy Inference Systems (ANFIS. The model is simulated and the results are evaluated at macroscopic level with the fixed time model, currently operating in Bogota-Colombia.

  8. Mortes no trânsito do Rio de Janeiro, Brasil

    Directory of Open Access Journals (Sweden)

    Klein Carlos Henrique

    1994-01-01

    Full Text Available A evolução urbana do município do Rio de Janeiro durante o século XX, especialmente a partir da sua segunda metade, é fortemente marcada por crescentes privilégios concedidos ao crescimento da utilização dos meios de transporte de massa e, principalmente, individuais, feitos por veículos a motor de explosão. Uma das conseqüências desta política é a ascenção da mortalidade por acidentes de trânsito, verificada durante a década de 80, entre homens e mulheres de todas as idades. Neste trabalho demonstra-se também que, em 1990, apenas cerca de 1/3 das vítimas fatais nos acidentes de trânsito estavam "embarcadas" nos veículos. Portanto, a maioria dos óbitos por este tipo de acidente, cerca de 2/3, ocorreu por atropelamentos. Isto indica a necessidade de o poder público reverter a prioridade na prevenção das mortes por acidentes de trânsito em favor de medidas eficazes que protejam os pedestres.

  9. Mortes no trânsito do Rio de Janeiro, Brasil

    Directory of Open Access Journals (Sweden)

    Carlos Henrique Klein

    Full Text Available A evolução urbana do município do Rio de Janeiro durante o século XX, especialmente a partir da sua segunda metade, é fortemente marcada por crescentes privilégios concedidos ao crescimento da utilização dos meios de transporte de massa e, principalmente, individuais, feitos por veículos a motor de explosão. Uma das conseqüências desta política é a ascenção da mortalidade por acidentes de trânsito, verificada durante a década de 80, entre homens e mulheres de todas as idades. Neste trabalho demonstra-se também que, em 1990, apenas cerca de 1/3 das vítimas fatais nos acidentes de trânsito estavam "embarcadas" nos veículos. Portanto, a maioria dos óbitos por este tipo de acidente, cerca de 2/3, ocorreu por atropelamentos. Isto indica a necessidade de o poder público reverter a prioridade na prevenção das mortes por acidentes de trânsito em favor de medidas eficazes que protejam os pedestres.

  10. TR-PIV Performance Test for a Flow Field Measurement in a Single Rod Test Section

    International Nuclear Information System (INIS)

    Park, Ju Yong; Shin, Chang Hwan; Lee, Chi Young; Oh, Dong Seok; In, Wang Kee

    2011-01-01

    For large enhancement of performance of Pressurized Water Reactor(PWR), dual-cooled fuel is being developed in Korea Atomic Energy Research Institute(KAERI). This nuclear fuel is a ring shape fuel which is different from conventional cylindrical nuclear fuel and cooling water flows both inner and outer channel. For this fuel, it widens the surface area. But it is bigger outer diameter of fuel rods. So, interval between fuel rods narrows. This because of outer channel flow is unstable. So, measurement of turbulence flow and perturbation that influence in heat transfer elevation is important.. To understand heat transfer characteristics by turbulence, measurement of flow perturbation element is necessary. To measure these turbulence characteristics, hot wire anemometer is widely used. However, it has many disadvantages such as low durability of prove, and big probe size. For these reasons, TR-PIV(Time-Resolved Particle Image Velocimetry) system is employed for better flow measurement in our research institute. TR-PIV system is consisted of laser system and high-speed camera that have high frequency. So, was judged that can measurement complicated turbulence flow and perturbation. In this paper, introduce TR-PIV system, and with results acquiring in single rod flow through this system, and wish to introduce about after this practical use plan

  11. Involvement of TR3/Nur77 translocation to the endoplasmic reticulum in ER stress-induced apoptosis

    International Nuclear Information System (INIS)

    Liang Bin; Song Xuhong; Liu Gefei; Li Rui; Xie Jianping; Xiao Lifeng; Du Mudan; Zhang Qiaoxia; Xu Xiaoyuan; Gan Xueqiong; Huang Dongyang

    2007-01-01

    Nuclear orphan receptor TR3/Nur77/NGFI-B is a novel apoptotic effector protein that initiates apoptosis largely by translocating from the nucleus to the mitochondria, causing the release of cytochrome c. However, it is possible that TR3 translocates to other organelles. The present study was designed to determine the intracellular localization of TR3 following CD437-induced nucleocytoplasmic translocation and the mechanisms involved in TR3-induced apoptosis. In human neuroblastoma SK-N-SH cells and human esophageal squamous carcinoma EC109 and EC9706 cells, 5 μM CD437 induced translocation of TR3 to the endoplasmic reticulum (ER). This distribution was confirmed by immunofluorescence analysis, subcellular fractionation analysis and coimmunoprecipitation analysis. The translocated TR3 interacted with ER-targeting Bcl-2; initiated an early release of Ca 2+ from ER; resulted in ER stress and induced apoptosis through ER-specific caspase-4 activation, together with induction of mitochondrial stress and subsequent activation of caspase-9. Our results identified a novel distribution of TR3 in the ER and defined two parallel mitochondrial- and ER-based pathways that ultimately result in apoptotic cell death

  12. T1-weighted vs. short-TE-long-TR images. Usefulness for knee MR examinations of ligament and meniscal lesions

    Energy Technology Data Exchange (ETDEWEB)

    Endo, Hideho; Wada, Mitsuyoshi; Shiotani, Seiji [Tsukuba Medical Center Hospital, Ibaraki (Japan); Niitsu, Mamoru; Itai, Yuji

    2000-11-01

    The purpose of this study was to compare short-TE-long-TR images with T1-weighed images in knee MR examinations. Sagittal MR images of the knee were obtained in 31 patients with knee pain. T1-weighted images were obtained by the spin-echo technique (TR/TE =350/15), and short-TE-long-TR images by fast spin-echo (TR/TE =1300/15) with an echo-train length of 5. Contrast-to-noise-ratios (CNRs) of the anterior cruciate ligament and synovial space, meniscus and articular cartilage, and meniscal lesion and normal meniscus were compared between short-TE-long-TR images and T1-weighted images. On each of the three examinations, short-TE-long-TR images provided significantly higher CNRs than T1-weighted images. It was concluded that short-TE-long-TR images can be a useful alternative to T1-weighted images in evaluating the anterior cruciate ligament and meniscal lesions. (author)

  13. T1-weighted vs. short-TE-long-TR images. Usefulness for knee MR examinations of ligament and meniscal lesions

    International Nuclear Information System (INIS)

    Endo, Hideho; Wada, Mitsuyoshi; Shiotani, Seiji; Niitsu, Mamoru; Itai, Yuji

    2000-01-01

    The purpose of this study was to compare short-TE-long-TR images with T1-weighed images in knee MR examinations. Sagittal MR images of the knee were obtained in 31 patients with knee pain. T1-weighted images were obtained by the spin-echo technique (TR/TE =350/15), and short-TE-long-TR images by fast spin-echo (TR/TE =1300/15) with an echo-train length of 5. Contrast-to-noise-ratios (CNRs) of the anterior cruciate ligament and synovial space, meniscus and articular cartilage, and meniscal lesion and normal meniscus were compared between short-TE-long-TR images and T1-weighted images. On each of the three examinations, short-TE-long-TR images provided significantly higher CNRs than T1-weighted images. It was concluded that short-TE-long-TR images can be a useful alternative to T1-weighted images in evaluating the anterior cruciate ligament and meniscal lesions. (author)

  14. Estudio sobre la distribución de tráfico autosimilar en redes Wi-Fi

    OpenAIRE

    Pérez, Santiago; Facchini, Higinio Alberto; Mercado, Gustavo; Taffernaberry, Juan Carlos; Bisaro, Luis

    2012-01-01

    Los modelos exactos del tráfico Ethernet y Wireless 802.11 son importantes para modelar las aplicaciones de capa superior y los buffers de memoria de switchs, APs y bridges. Los análisis de cola realizados suponiendo la naturaleza Poisson del tráfico de datos difieren significativamente del rendimiento observado en la realidad. Diversos estudios han demostrado que para algunos entornos el patrón de tráfico es autosimilar, en lugar de Poisson. Desde principios de los años 90 se comenzaron a pu...

  15. Aplicaciones del modelo On/Off al tráfico agregado en las redes de comunicaciones

    OpenAIRE

    Parra León, Andrés; Piedrahita, Elkin M; Salcedo, Octavio

    2011-01-01

    Los modelos que permiten recrear trazas de tráfico generadas en una red de comunicaciones, pueden utilizarse en predicciones y estimaciones de tráfico a fin de optimizar el uso de los recursos de la red; uno de estos es el modelo On/Off, el cual permite describir el comportamiento del tráfico agregado por una o más fuentes de información. La importancia de este artículo se centra en la incidencia que dicho modelo ha tenido al aplicarse en diversas tecnologías de comunicaciones, para esto se e...

  16. Gümnaasiumi trükkal ja keskvõimu korralduste publitseerimine 17. sajandi lõpu Tallinnas / Kaarel Vanamölder

    Index Scriptorium Estoniae

    Vanamölder, Kaarel, 1981-

    2011-01-01

    Trükkal Christoph Brendekenist. Trükkali sissetulekutest ja töö est küsitavast tasust. Plakatite tiraažist. Kindralkuberneri kantselei publitseerimisrutiinist ning korralduste edastamise kiirusest

  17. Electrochemical performance in the hydrogen evolution reaction of Ni-TR (TR= La, Ce) materials synthesized using the solid state reaction method; Desempeno electroquimico en la reaccion de evolucion de hidrogeno de materiales de electrodo Ni-TR (TR = La, Ce) sintetizados por el metodo de reaccion de estado solido

    Energy Technology Data Exchange (ETDEWEB)

    Torres-Huerta, A. M.; Dominguez-Crespo, M. A.; Ramirez-Meneses, E.; Yanez-Zamora, C. [CICATA, IPN, Altamira, Tamaulipas (Mexico); Avila-Garcia, I. [IPN, ESIQIE, UPALM, Mexico, D.F. (Mexico)]. E-mail: mdominguezc@ipn.mx; adcrespo2000@yahoo.com.mx

    2009-09-15

    At the industrial level, the use of fuel cell technology is still limited because of the high costs of its parts and costs related to its operations. Although the electrode material with greater electroactivity is Pt, because of its high cost, alternative electrocatalysts have been sought that balance cost and activity. One of the materials that have been most widely used is nickel, along with some of its alloys. This material has shown good performance using low overpotentials in traditional reactions such as hydrogen (HER) and oxygen (OER) evolution, as well as high resistance to corrosion and low costs. In particular, binary and ternary alloys have shown significant increases in HER activity when compared to materials in the pure or massive state. Therefore, in the search for new alternatives with acceptable efficiency and low-cost, this work obtained Ni-TR (TR = La, Ce) using solid-state reaction with metallic acetylacetonates and metallic powder. These materials were synthesized for 3 h at different temperatures (795 or 920, 1000 and 1200 degrees Celsius) in order to evaluate the effect on the electrochemical performance of the electrocatalysts. The structural and morphological characterization of materials was performed with XRD and SEM techniques, respectively. In addition, the electrochemical performance of electrode materials was evaluated with HER using cyclic voltametry (CV) and potentiodynamic curves. The results obtained show that a combination of oxides was obtained (NiO, CeO{sub 2} and LaNiO{sub 3}) at low temperatures; nonetheless, as the synthesis temperatures increase, NiO-CeO{sub 2} and NiO-LaNiO{sub 3} alloys are formed, respectively. A clear dependence was also observed between electrocatalytic activity and the source for obtaining these materials(Ni-TR). [Spanish] A nivel industrial, el uso de la tecnologia de celdas de combustible esta todavia limitada debido sobre todo a los altos costos de las partes que la constituyen y los costos

  18. Study on the curie transition of P(VDF-TrFE) copolymer

    Science.gov (United States)

    Eka Septiyani Arifin, Devi; Ruan, J. J.

    2018-01-01

    A systematic study was carried out to decipher the mechanism of Curie transition of piezoelectric crystals of poly(vinylidene fluoride trifluoroethylene) P(VDF-TrFE). The unique polarity of P(VDF-TrFE) crystalline phase below curie transition temperature is attributed to the lattice packing of all-trans molecular chains, which allocates all the substituted fluorine atoms on one side of molecular chains and hydrogen atoms on the other side. Therefore, a net dipole moment is created across the lateral packing of molecular chains. Nevertheless, due to the mutual repulsion among fluorene atoms, this all-trans conformation is not stable, and ready to change above Curie temperature, where thermal kinetic energy is sufficient to cause segmental rotation. As being illustrated by in-situ recorded X-ray diffraction and thermal analysis, the concerned curie transition is deciphered as a one-step process which is involved two process and this is different from conventional one-step solid-solid transitions. Accompanied with this one-step process during heating, the occurrence of lamellar bending is inferred for elucidating the decline of stacking regularity of crystalline lamellae, which reversibly recover during subsequent cooling. However, as the crystalline lamellae of P(VDF-TrFE) are confined in between the stacking of crystalline lamellae of PVDF, lamellar bending is restricted accordingly. As a result, a certain fraction of the piezoelectric crystalline lamellae was found to survive through the Curie transition. Thus, in addition to the suggestion of a one-step process as a new concept for understanding the Curie transition, the relationship between the lamellar stacking and transition of molecular packing is unveiled as well in this research.

  19. A Spitzer five-band analysis of the Jupiter-sized planet TrES-1

    Energy Technology Data Exchange (ETDEWEB)

    Cubillos, Patricio; Harrington, Joseph; Foster, Andrew S. D.; Lust, Nate B.; Hardy, Ryan A.; Bowman, M. Oliver [Planetary Sciences Group, Department of Physics, University of Central Florida, Orlando, FL 32816-2385 (United States); Madhusudhan, Nikku, E-mail: pcubillos@fulbrightmail.org [Department of Physics and Department of Astronomy, Yale University, New Haven, CT 06511 (United States)

    2014-12-10

    With an equilibrium temperature of 1200 K, TrES-1 is one of the coolest hot Jupiters observed by Spitzer. It was also the first planet discovered by any transit survey and one of the first exoplanets from which thermal emission was directly observed. We analyzed all Spitzer eclipse and transit data for TrES-1 and obtained its eclipse depths and brightness temperatures in the 3.6 μm (0.083% ± 0.024%, 1270 ± 110 K), 4.5 μm (0.094% ± 0.024%, 1126 ± 90 K), 5.8 μm (0.162% ± 0.042%, 1205 ± 130 K), 8.0 μm (0.213% ± 0.042%, 1190 ± 130 K), and 16 μm (0.33% ± 0.12%, 1270 ± 310 K) bands. The eclipse depths can be explained, within 1σ errors, by a standard atmospheric model with solar abundance composition in chemical equilibrium, with or without a thermal inversion. The combined analysis of the transit, eclipse, and radial-velocity ephemerides gives an eccentricity of e=0.033{sub −0.031}{sup +0.015}, consistent with a circular orbit. Since TrES-1's eclipses have low signal-to-noise ratios, we implemented optimal photometry and differential-evolution Markov Chain Monte Carlo (MCMC) algorithms in our Photometry for Orbits, Eclipses, and Transits pipeline. Benefits include higher photometric precision and ∼10 times faster MCMC convergence, with better exploration of the phase space and no manual parameter tuning.

  20. GPS data til undersøgelse af trængsel

    DEFF Research Database (Denmark)

    Andersen, Ove; Krogh, Benjamin Bjerre; Torp, Kristian

    GPS data fra køretøjer er i en årrække blevet brugt som grundlag for beregning af køretider [1] [2] og estimering af trængsel [3] . Fælles for de tidligere tiltag er, at der typisk er anvendt både kommercielt software og et kommercielt digitalt kort. Sådanne kommercielle løsninger kræver, at brug......GPS data fra køretøjer er i en årrække blevet brugt som grundlag for beregning af køretider [1] [2] og estimering af trængsel [3] . Fælles for de tidligere tiltag er, at der typisk er anvendt både kommercielt software og et kommercielt digitalt kort. Sådanne kommercielle løsninger kræver....... Open-source og creative-commons licenserne gør, at information frit kan distribueres. Som et eksempel anvendes køretidskortet til at estimere køretider for flex-transport for store dele af Danmark. Artiklen er struktureret som følgende. Først præsenteres, hvorledes GPS data og OSM kortet er anvendt til...... at skabe et hastigheds- og trængselskort for hele Danmark. Herefter vises det, hvorledes GPS data inddelt i ture kan anvendes til at analysere kortere strækninger (nogle kilometer) f.eks. hvor der skal være grønne bølger. Slutteligt vises, hvordan GPS data kan anvendes til at nærstudere et enkelt kryds...

  1. Cross checking of the new capabilities of the fuel cycle scenario code TR-EVOL - 5229

    International Nuclear Information System (INIS)

    Merino-Rodriguez, I.; Garcia-Martinez, M.; Alvarez-Velarde, F.

    2015-01-01

    This work is intended to cross check the new capabilities of the fuel cycle scenario code TR-EVOL by means of comparing its results with those published in bibliography. This process has been divided in two stages as follows. The first stage is dedicated to check the improvements in the material management part of the fuel cycle code (the nuclear fuel mass balance estimation). The Spanish nuclear fuel cycle has been chosen as the model for the mass balance comparison given that the fuel mass per reactor is available in bibliography. The second stage has been focused in verifying the validity of the TR-EVOL economic module. The economic model verification has been carried out by making use of the ARCAS EU project and its economic assessments for advanced reactors and scenarios involving fast reactors and ADS. As conclusions, the main finding from the first stage includes that TR-EVOL provides a prediction of mass values quite accurate after the improvements and when using the proper parameters as input for the code. For the second stage, results were highly satisfactory since a difference smaller than 3% can be found regarding results published by the ARCAS project (NRG estimations). Furthermore, concerning the Decommissioning, Dismantling and Disposal cost, results are highly acceptable (7% difference in the comparison with the final disposal in a once-through scenario and around 11% in a final disposal with a reprocessing strategy) given the difficulties to find in bibliography detailed information about the costs of the final disposals and the significant uncertainties involved in design concepts and related unit costs

  2. Characteristics of a pressure sensitive touch sensor using a piezoelectric PVDF-TrFE/MoS2 stack

    International Nuclear Information System (INIS)

    Park, Woojin; Yang, Jin Ho; Kang, Chang Goo; Lee, Young Gon; Hwang, Hyeon Jun; Kang, Soo Cheol; Lee, Sang Kyung; Lee, Byoung Hun; Cho, Chunhum; Lim, Sung Kwan; Lee, Sangchul; Hong, Woong-Ki

    2013-01-01

    A new touch sensor device has been demonstrated with molybdenum disulfide (MoS 2 ) field effect transistors stacked with a piezoelectric polymer, polyvinylidene fluoride–trifluoroethylene (PVDF–TrFE). The performance of two device stack structures, metal/PVDF–TrFE/MoS 2 (MPM) and metal/PVDF–TrFE/Al 2 O 3 /MoS 2 (MPAM), were compared as a function of the thickness of PVDF–TrFE and Al 2 O 3 . The sensitivity of the touch sensor has been improved by two orders of magnitude by reducing the charge scattering and enhancing the passivation effects using a thin Al 2 O 3 interfacial layer. Reliable switching behavior has been demonstrated up to 120 touch press cycles. (paper)

  3. Evolução dos acidentes de trânsito em um grande centro urbano, 1991-2000

    OpenAIRE

    Oliveira,Zenaide Calazans de; Mota,Eduardo Luiz Andrade; Costa,Maria da Conceição N.

    2008-01-01

    Este estudo descreve a evolução dos acidentes de trânsito em Salvador, Bahia, Brasil, entre 1991 e 2000, utilizando-se dados do Departamento Estadual de Trânsito do Estado da Bahia. Calculou-se taxas globais dos acidentes de trânsito, vítimas e taxas padronizadas de mortalidade por habitante e por veículos, e comparou-se médias destes indicadores para antes (1991 a 1994) e após (1995 a 2000) a adoção de medidas de intervenção como o uso do cinto de segurança e o Código Nacional de Trânsito. A...

  4. Monitoração de tráfego par-a-par em tempo real

    OpenAIRE

    Tiago Alves Macambira

    2005-01-01

    O tráfego devido a aplicações P2P tem aumentado consideravelmente nos últimos anos e, apesar de ser hoje o responsável pela maior parte de todo o tráfego da Internet, não existem muitas ferramentas que auxiliem na monitoração e portanto no entendimento desse tráfego, tanto sob um ponto de vista acadêmico como sob um ponto de vista prático. Nesse trabalho abordamos as dificuldades em se construir umasolução que viabilize a análise e a caracterização de tráfego de aplicações em tempo real, tend...

  5. A Comparison of DSM-IV-TR and DSM-5 Diagnostic Classifications in the Clinical Diagnosis of Autistic Spectrum Disorder.

    Science.gov (United States)

    Yaylaci, Ferhat; Miral, Suha

    2017-01-01

    Aim of this study was to compare children diagnosed with Pervasive Developmental Disorder (PDD) according to DSM-IV-TR and DSM-5 diagnostic systems. One hundred fifty children aged between 3 and 15 years diagnosed with PDD by DSM-IV-TR were included. PDD symptoms were reviewed through psychiatric assessment based on DSM-IV-TR and DSM-5 criteria. Clinical severity was determined using Childhood Autism Rating Scale (CARS) and Autism Behavior Checklist (ABC). A statistically significant decrease (19.3 %) was detected in the diagnostic ratio with DSM-5. Age and symptom severity differed significantly between those who were and were not diagnosed with PDD using DSM-5. B4 criteria in DSM-5 was most common criterion. Results indicate that individuals diagnosed with PDD by DSM-IV-TR criteria may not be diagnosed using DSM-5 criteria.

  6. Nadležnost upravnih sudova u zaštiti tržišnog natjecanja

    Directory of Open Access Journals (Sweden)

    Lidija Rostaš-Beroš

    2014-01-01

    Full Text Available U radu se razmatra nadležnost upravnih sudova kroz do sada donesene zakone o zaštiti tržišnog natjecanja u Republici Hrvatskoj. Kako su se mijenjali propisi kojima je uređivana zaštita tržišnog natjecanja, hrvatsko pravo tržišnog natjecanja sve se više usklađivalo s europskim pravom, što je bila i namjera s obzirom na pripreme, a zatim i ulazak Republike Hrvatske u članstvo Europske unije. Međutim, iz istog razloga je provedena i reorganizacija upravnog sudovanja pa su se mijenjali i upravni sudovi nadležni za ocjenjivanje zakonitosti akata donesenih u postupcima kontrole poštovanja pravila o tržišnom natjecanju.

  7. Test your memory-Turkish version (TYM-TR): reliability and validity study of a cognitive screening test.

    Science.gov (United States)

    Maviş, Ilknur; Özbabalik Adapinar, Belgin Demet; Yenilmez, Çinar; Aydin, Ayşe; Olgun, Engin; Bal, Cengiz

    2015-01-01

    The test your memory (TYM) is reported to be a sensitive cognitive function assessment scale for people with dementia. The aim of the present study was to investigate the reliability and validity of an adapted Turkish version of the TYM (TYM-TR) among Turkish dementia patients. The TYM-TR was given to 59 patients with dementia aged 60+ and 336 normal controls aged 23-75+. The diagnostic utility of the TYM-TR was compared with that of the mini-mental state examination (MMSE) to validate it. The internal consistency of the TYM-TR was a = 0.85. The test-retest reliability was 0.97 (P reliability and validity to distinguish dementia in the Turkish population.

  8. InGaP DHBT for High Efficiency L-band T/R Module, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — A fully monolithically integrated L-band T/R module using InGaP/GaAs-based HBTs (heterojunction bipolar transistors) for both the transmit and receive functions is...

  9. Reposição de nutrientes durante três cultivos de alface em hidroponia

    Directory of Open Access Journals (Sweden)

    Backes Fernanda Alice A.L.

    2003-01-01

    Full Text Available O experimento foi realizado em estufa plástica na UFSM, de agosto a novembro/99. Avaliou-se cinco formas de reposição de nutrientes na solução nutritiva com base na condutividade elétrica (CE, no sistema 'NFT' (Nutrient Film Technique e duas cultivares de alface: Regina e Deisy, cultivadas em bancadas de sustentação formadas por telhas de fibro-cimento revestidas com tinta betuminosa Neutrolâ. Foram dispostas 14 plantas por canal para cada repetição e uma cultivar em cada três canais, totalizando 84 plantas por bancada de produção. Comparou-se a eficiência de métodos de reposição de nutrientes na produção de alface, assim como a utilização da mesma solução, com reposição de nutrientes, durante três cultivos consecutivos. O delineamento experimental foi de blocos casualizados, com três repetições, em esquema fatorial 5x2. Os resultados demonstraram que o desempenho das cultivares avaliadas não foi influenciado pelos métodos de reposição de nutrientes. A ausência de reposição de nutrientes na solução nutritiva, durante um cultivo, permitiu maior produtividade da cultura, não se recomendando a reposição quando o objetivo for renovar a solução ao final do cultivo. As formas de reposição de nutrientes na solução nutritiva, durante o primeiro e segundo cultivos, não alteraram a produtividade da cultura em relação à renovação completa da solução nutritiva ao final do cultivo hidropônico. Para a reutilização de solução nutritiva, recomenda-se a reposição de nutrientes sempre que a CE diminuir 50% da inicial, possibilitando a produção por pelo menos três cultivos.

  10. Robust, Rework-able Thermal Electronic Packaging: Applications in High Power TR Modules for Space

    Science.gov (United States)

    Hoffman, James Patrick; Del Castillo, Linda; Hunter, Don; Miller, Jennifer

    2012-01-01

    The higher output power densities required of modern radar architectures, such as the proposed DESDynI [Deformation, Ecosystem Structure, and Dynamics of Ice] SAR [Synthetic Aperture Radar] Instrument (or DSI) require increasingly dense high power electronics. To enable these higher power densities, while maintaining or even improving hardware reliability, requires improvements in integrating advanced thermal packaging technologies into radar transmit/receive (TR) modules. New materials and techniques have been studied and are now being implemented side-by-side with more standard technology typically used in flight hardware.

  11. Northrop Grumman TR202 LOX/LH2 Deep Throttling Engine Project Status

    Science.gov (United States)

    Gromski, J.; Majamaki, A. N.; Chianese, S. G.; Weinstock, V. D.; Kim, T.

    2010-01-01

    NASA's Propulsion and Cryogenic Advanced Development (PCAD) project is currently developing enabling propulsion technologies in support of the Exploration Initiative, with a particular focus on the needs of the Altair Project. To meet Altair requirements, several technical challenges need to be overcome, one of which is the ability for the lunar descent engine(s) to operate over a deep throttle range with cryogenic propellants. To address this need, PCAD has enlisted Northrop Grumman Aerospace Systems (NGAS) in a technology development effort associated with the TR202, a LOX/LH2 expander cycle engine driven by independent turbopump assemblies and featuring a variable area pintle injector similar to the injector used on the TR200 Apollo Lunar Module Descent Engine (LMDE). Since the Apollo missions, NGAS has continued to mature deep throttling pintle injector technology. The TR202 program has completed two phases of pintle injector testing. The first phase of testing used ablative thrust chambers and demonstrated igniter operation as well as stable performance at several power levels across the designed 10:1 throttle range. The second phase of testing was performed on a calorimeter chamber and demonstrated injector performance at various power levels (75%, 50%, 25%, 10%, and 7.5%) across the throttle range as well as chamber heat flux to show that the engine can close an expander cycle design across the throttle range. This paper provides an overview of the TR202 program. It describes the different phases of the program with the key milestones of each phase. It then shows when those milestones were met. Next, it describes how the test data was used to update the conceptual design and how the test data has created a database for deep throttling cryogenic pintle technology that is readily scaleable and can be used to again update the design once the Altair program's requirements are firm. The final section of the paper describes the path forward, which includes

  12. The Transit Light Curve Project. VIII. Six Occultations of the Exoplanet TrES-3

    OpenAIRE

    Winn, Joshua N.; Holman, Matthew J.; Shporer, Avi; Fernandez, Jose; Mazeh, Tsevi; Latham, David W.; Charbonneau, David; Everett, Mark E.

    2008-01-01

    We present photometry of the exoplanet host star TrES-3 spanning six occultations (secondary eclipses) of its giant planet. No flux decrements were detected, leading to 99%-confidence upper limits on the planet-to-star flux ratio of 0.00024, 0.0005, and 0.00086 in the i, z, and R bands respectively. The corresponding upper limits on the planet's geometric albedo are 0.30, 0.62, and 1.07. The upper limit in the i band rules out the presence of highly reflective clouds, and is only a factor of ...

  13. Trânsito religioso e reinvenções femininas do sagrado na modernidade

    Directory of Open Access Journals (Sweden)

    Sandra Duarte de Souza

    2009-05-01

    Full Text Available O trânsito religioso é indicador de que os “modelos oficiais e religião” têm sido substituídos, ou coexistem com  oferenciais religiosos cambiantes, respondendo à demanda dos sujeitos de fé. Os anseios de significação imediata dos sujeitos de fé encontram na “vagabundagem religiosa” sua atitude mais coerente. A vagabundagem semântica dos crentes infiéis é o elemento dinamizador do campo religioso moderno. No presente texto nos propomos a discutir o trânsito religioso de mulheres, suas motivações e as implicações dessa “andança religiosa” para a concepção que estas têm a respeito do sagrado. Para tanto nos utilizamos e dados de nossa pesquisa de campo realizada para a Universidade Católica de Goiás no ano 2000 em Alto Paraíso – GO, bem como de dados obtidos em pesquisa que realizamos para a Universidade Metodista de São Paulo na cidade de São Bernardo do Campo – SP em 2003, como parte do projeto intitulado: “Religiosidade caleidoscópica – nomadismo espiritual: implicações de gênero”. Os resultados da pesquisa indicaram um trânsito maior das mulheres por força das representações de gênero.Palavras-chave: Trânsito religioso; Secularização; Gênero.ABSTRACTReligious transit indicates that ‘official models of religion’ have been replaced, or coexist with mutable religious references, answering the believers’ demand. Their desire for immediate signification finds their most coherent attitude in ‘religious nomadism’. Unfaithful believers’ semantic nomadism is the dynamic element of modern religion. This text discusses women’s religious transit, their motivations and the implications of that ‘religious walk’ to their conception of the sacred. The date used are from a field research for the Universidade Católica de Goiás, developed in Alto Paraíso - State of Goiás, in 2000, and from a research for the Universidade Metodista de São Paulo, carried out in São Bernardo do

  14. TR146 cells grown on filters as a model of human buccal epithelium

    DEFF Research Database (Denmark)

    Nielsen, Hanne Mørck; Verhoef, J C; Ponec, M

    1999-01-01

    The aim of the present study was to characterize the TR146 cell culture model as an in vitro model of human buccal epithelium with respect to the permeability of test substances with different molecular weights (M(w)). For this purpose, the apparent permeability (P(app)) values for mannitol...... and for fluorescein isothiocyanate (FITC)-labelled dextrans (FD) with various M(w) (4000-40000) were compared to the P(app) values obtained using porcine buccal mucosa as an in vitro model of the human buccal epithelium. The effect of 10 mM sodium glycocholate (GC) on the P(app) values was examined. To identify...

  15. Nietzsche e a jubilosa experiência trágica dos gregos

    Directory of Open Access Journals (Sweden)

    Renato Nunes Bittencourt

    2010-10-01

    Full Text Available Neste texto analisamos a interpretação de Nietzsche sobre o sentido existencial da experiência trágica realizada pelos antigos gregos na celebração estética e religiosa da Tragédia Ática, e de que modo tal experiência favorece a compreensão imanente e amoral da vida, suprimindo-se ainda qualquer tipo de depreciação moralista em relação ao real.

  16. Pseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-U

    DEFF Research Database (Denmark)

    Davis, Matti; Hatzubai, Ada; Andersen, Jens S

    2002-01-01

    in the nucleus. Here we report the isolation of the major E3RS-associated protein, hnRNP-U, an abundant nuclear phosphoprotein. This protein occupies E3RS in a specific and stoichiometric manner, stabilizes the E3 component, and is likely responsible for its nuclear localization. hnRNP-U binding was abolished....... Consequently, hnRNP-U engages a highly neddylated active SCF(beta-TrCP), which dissociates in the presence of a high-affinity substrate, resulting in ubiquitination of the latter. Our study points to a novel regulatory mechanism, which secures the localization, stability, substrate binding threshold...

  17. Desempenho de vacas Charolês e Nelore desterneiradas aos três ou sete meses

    Directory of Open Access Journals (Sweden)

    Restle João

    2001-01-01

    Full Text Available Foi avaliado o desempenho de vacas Charolês (C e Nelore (N, agrupadas em três classes de idade, jovens (3 e 4 anos, adultas (5 a 7 anos e velhas (8 ou mais anos, desmamadas aos três (precoce ou sete meses no outono (tradicional. O peso no outono das vacas desterneiradas aos três meses (T3 foi 45 kg superior ao das vacas com remoção do bezerro aos sete meses (T7. O estado corporal aos sete meses também foi melhor nas vacas do T3 (3,3 contra 2,1 pontos. Vacas do T3 apresentaram maior ganho de peso do parto ao final do período reprodutivo e apresentaram maiores porcentagem de cio (81 contra 51% e prenhez (67,2 contra 37,3% e menor intervalo do parto ao primeiro cio pós-parto (102 contra 114 dias que vacas do T7. Vacas adultas apresentaram melhor estado corporal aos sete meses e tiveram melhor desempenho reprodutivo do que vacas velhas e jovens. A diferença na porcentagem de prenhez entre o T3 e T7 foi mais evidente nas vacas jovens (42,11 contra 12,5% e velhas (51,72 contra 35,71% que nas adultas (62,50 contra 53,33%. Vacas C foram mais pesadas que as N, ao parto, aos três e sete meses pós-parto e apresentaram melhor estado corporal aos sete meses. O efeito do desmame precoce no desempenho reprodutivo foi mais evidente nas vacas C. A porcentagem de fêmeas prenhes nas C foi de 80,60% para o T3 e 41,90% para o T7, já nas N as porcentagens foram de 45,50 e 30,00%, respectivamente, para o T3 e T7. Nas vacas C, a produção de leite e a amamentação apresentaram efeito inibidor, sobre a reprodução, mais marcante que nas vacas N.

  18. Longshore sediment transport in the Tróia-Sines Littoral Ribbon (SW Portugal).

    OpenAIRE

    Gama, Cristina; Taborda, Rui; Andrade, César

    2006-01-01

    Longshore sediment transport in the Tróia-Sines litoral ribbon was evaluated by map comparison and applying energy flux method using numerical models. Results yielded a longshore transport residual rate in the order of 10 5 m3y-1 towards north. The comparison of the results with the ones obtained thought the analysis of the secular coastline evolution show that the empirical coefficient between the energy flux and the longshore drift is equal to 0.28 and is apparently independent with grain ...

  19. Modelo para la expansión de la capacidad de tráfico

    OpenAIRE

    Aldás Sánchez, Milton Rodrigo

    2015-01-01

    Tesis Doctoral leída en la Universidad Rey Juan Carlos de Madrid en 2015. Directores de la Tesis: David Ríos Insúa y Marco Javier Flores Calero En esta tesis se estudian los problemas del flujo de tráfico y la congestión vehicular, más concretamente en el casco urbano de la ciudad de Ambato. Estos problemas se han agudizado en los últimos tiempos debido al crecimiento poblacional, el aumento de entidades educativas, bancarias y comerciales y, especialmente, el incremento excesi...

  20. Três fórmulas para compreender "O suicídio" de Durkheim

    OpenAIRE

    Teixeira, Ricardo Rodrigues

    2002-01-01

    Trata-se de um ensaio de interpretação da sociologia durkheimiana, a partir de uma breve contextualização de seu pensamento no quadro de uma certa visão da modernidade e de uma particular leitura de sua obra "O Suicídio". Dividido em três partes, o texto procura explorar alguns sentidos desta Sociologia, ao mesmo tempo que expõe uma de suas possíveis aporias. This is an essay interpreting the sociology of Durkheim, based on a brief contextualization of his thoughts within the scope of a gi...

  1. La conducta social en el tráfico: Fundamentos para la intervención.

    OpenAIRE

    Alonso Plá, Francisco Manuel; Esteban Martínez, Cristina; Calatayud Miñana, Constanza; Pastor Soriano, Juan Carlos; Alamar Rocatí, Beatriz; Medina Sarmiento, José Eugenio

    2007-01-01

    En este libro nos hemos orientado hacia el estudio de lo “prosocial” frente a lo “antisocial”. Es decir hacia aquellas conductas que favorecen la ayuda entre las personas frente a aquellas que no son de ayuda, que llegan a atentar contra las mismas y por ende contra la sociedad en general. un ámbito de especial interés para nosotros será el del tráfico y la seguridad vial. La prosocialidad esté basada en una decisión interior que requiere, sin lugar a dudas, de un control personal dirigido...

  2. sA Comparison of DSM-IV-TR and DSM-5 Diagnostic Classifications in the Clinical Diagnosis of Autistic Spectrum Disorder

    Science.gov (United States)

    Yaylaci, Ferhat; Miral, Suha

    2017-01-01

    Aim of this study was to compare children diagnosed with Pervasive Developmental Disorder (PDD) according to DSM-IV-TR and DSM-5 diagnostic systems. One hundred fifty children aged between 3 and 15 years diagnosed with PDD by DSM-IV-TR were included. PDD symptoms were reviewed through psychiatric assessment based on DSM-IV-TR and DSM-5 criteria.…

  3. Choline transport via choline transporter-like protein 1 in conditionally immortalized rat syncytiotrophoblast cell lines TR-TBT.

    Science.gov (United States)

    Lee, N-Y; Choi, H-M; Kang, Y-S

    2009-04-01

    Choline is an essential nutrient for phospholipids and acetylcholine biosynthesis in normal development of fetus. In the present study, we investigated the functional characteristics of choline transport system and inhibitory effect of cationic drugs on choline transport in rat conditionally immortalized syncytiotrophoblast cell line (TR-TBT). Choline transport was weakly Na(+) dependent and significantly influenced by extracellular pH and by membrane depolarization. The transport process of choline is saturable with Michaelis-Menten constants (K(m)) of 68microM and 130microM in TR-TBT 18d-1 and TR-TBT 18d-2 respectively. Choline uptake in the cells was inhibited by unlabeled choline and hemicholinium-3 as well as various organic cations including guanidine, amiloride and acetylcholine. However, the prototypical organic cation tetraethylammonium and cimetidine showed very little inhibitory effect of choline uptake in TR-TBT cells. RT-PCR revealed that choline transporter-like protein 1 (CTL1) and organic cation transporter 2 (OCT2) are expressed in TR-TBT cells. The transport properties of choline in TR-TBT cells were similar or identical to that of CTL1 but not OCT2. CTL1 was also detected in human placenta. In addition, several cationic drugs such as diphenhydramine and verapamil competitively inhibited choline uptake in TR-TBT 18d-1 with K(i) of 115microM and 55microM, respectively. Our results suggest that choline transport system, which has intermediate affinity and weakly Na(+) dependent, in TR-TBT seems to occur through a CTL1 and this system may have relevance with the uptake of pharmacologically important organic cation drugs.

  4. Primary Tr1 cells from metastatic melanoma eliminate tumor-promoting macrophages through granzyme B- and perforin-dependent mechanisms.

    Science.gov (United States)

    Yan, Hongxia; Zhang, Ping; Kong, Xue; Hou, Xianglian; Zhao, Li; Li, Tianhang; Yuan, Xiaozhou; Fu, Hongjun

    2017-04-01

    In malignant melanoma, tumor-associated macrophages play multiple roles in promoting tumor growth, such as inducing the transformation of melanocytes under ultraviolet irradiation, increasing angiogenesis in melanomas, and suppressing antitumor immunity. Because granzyme B- and perforin-expressing Tr1 cells could specifically eliminate antigen-presenting cells of myeloid origin, we examined whether Tr1 cells in melanoma could eliminate tumor-promoting macrophages and how the interaction between Tr1 cells and macrophages could affect the growth of melanoma cells. Tr1 cells were characterized by high interleukin 10 secretion and low Foxp3 expression and were enriched in the CD4 + CD49b + LAG-3 + T-cell fraction. Macrophages derived from peripheral blood monocytes in the presence of modified melanoma-conditioned media demonstrated tumor-promoting capacity, exemplified by improving the proliferation of cocultured A375 malignant melanoma cells. But when primary Tr1 cells were present in the macrophage-A375 coculture, the growth of A375 cells was abrogated. The conventional CD25 + Treg cells, however, were unable to inhibit macrophage-mediated increase in tumor cell growth. Further analyses showed that Tr1 cells did not directly eliminate A375 cells, but mediated the killing of tumor-promoting macrophages through the secretion of granzyme B and perforin. The tumor-infiltrating interleukin 10 + Foxp3 - CD4 + T cells expressed very low levels of granzyme B and perforin, possibly suggested the downregulation of Tr1 cytotoxic capacity in melanoma tumors. Together, these data demonstrated an antitumor function of Tr1 cells through the elimination of tumor-promoting macrophages, which was not shared by conventional Tregs.

  5. The development of a XEOL and TR XEOL detection system for the I18 microfocus beamline Diamond light source

    International Nuclear Information System (INIS)

    Taylor, R.P.; Finch, A.A.; Mosselmans, J.F.W.; Quinn, P.D.

    2013-01-01

    We describe the design and capabilities of a new Continuous Wave X-ray Excited Optical Luminescence (CW-XEOL) and Time Resolved X-ray Excited Optical Luminescence (TR-XEOL) facility on the I18 beamline at the DIAMOND light source, the UK national synchrotron facility. Experimental data from a suite of framework silicates are presented to illustrate the capabilities of the system. Experiments studied include simple (CW-XEOL) spectroscopy, (TR XEOL) lifetime experiments dose and dose rate dependence (CW-XEOL) experiments, spatial (TR XEOL) on heterogeneous sample, wavelength resolved (TR XEOL), Optically Derived X-ray Absorption Spectroscopy, (OD XAS). - Highlights: ► We describe the capabilities of a new CW-XEOL and TR-XEOL detection system for a hard X-ray beamline. ► We model TR XEOL with luminescence lifetimes from ∼25 ps to ∼400 ps from framework silicates. ► CW XEOL, 200–900 nm with a resolution of ∼0.9 nm is used to complete dose and dose rate experiments. ► Micro-beam high spatial resolution XEOL within X-ray excitation energies 2–20 keV.

  6. Amyloid formation and disaggregation of α-synuclein and its tandem repeat (α-TR)

    International Nuclear Information System (INIS)

    Bae, Song Yi; Kim, Seulgi; Hwang, Heejin; Kim, Hyun-Kyung; Yoon, Hyun C.; Kim, Jae Ho; Lee, SangYoon; Kim, T. Doohun

    2010-01-01

    Research highlights: → Formation of the α-synuclein amyloid fibrils by [BIMbF 3 Im]. → Disaggregation of amyloid fibrils by epigallocatechin gallate (EGCG) and baicalein. → Amyloid formation of α-synuclein tandem repeat (α-TR). -- Abstract: The aggregation of α-synuclein is clearly related to the pathogenesis of Parkinson's disease. Therefore, detailed understanding of the mechanism of fibril formation is highly valuable for the development of clinical treatment and also of the diagnostic tools. Here, we have investigated the interaction of α-synuclein with ionic liquids by using several biochemical techniques including Thioflavin T assays and transmission electron microscopy (TEM). Our data shows a rapid formation of α-synuclein amyloid fibrils was stimulated by 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide [BIMbF 3 Im], and these fibrils could be disaggregated by polyphenols such as epigallocatechin gallate (EGCG) and baicalein. Furthermore, the effect of [BIMbF 3 Im] on the α-synuclein tandem repeat (α-TR) in the aggregation process was studied.

  7. Calibration And Performance Verification Of LSC Packard 1900TR AFTER REPAIRING

    International Nuclear Information System (INIS)

    Satrio; Evarista-Ristin; Syafalni; Alip

    2003-01-01

    Calibration process and repeated verification of LSC Packard 1900TR at Hydrology Section-P3TlR has been done. In the period of middle 1997 to July 2000, the counting system of the instrument has damaged and repaired for several times. After repairing, the system was recalibrated and then verified. The calibration and verification were conducted by using standard 3 H, 14 C and background unquenched. The result of calibration shows that background count rates of 3 H and 14 C is 12.3 ± 0.79 cpm and 18.24 ± 0.69 cpm respectively; FOM 3 H and 14 C is 285.03 ± 15.95 and 641.06 ± 16.45 respectively; 3 H and 14 C efficiency is 59.13 ± 0.28 % and 95.09 ± 0.31 %. respectively. From the verification data's, the parameter of SIS and tSIE for 14 C is to be in range of limit. And then 3 H and 14 C efficiency is still above minimum limit. Whereas, the background fluctuation still show normal condition. It could be concluded that until now the performance of LSC Packard 1900TR is well condition and could be used for counting. (author)

  8. La metafilosofía de Eugenio Trías

    Directory of Open Access Journals (Sweden)

    Jonatan Caro Rey

    2016-01-01

    Full Text Available El artículo propone interpretar la metafilosofía de Eugenio Trías como un proyecto de liberación de la identidad (frente al subjetivismo paralelo a la liberación del discurso metafísico (frente a las actitudes antimetafísicas de la Teoría marxista —ortodoxa— de las ideologías y del positivismo lógico. En este intento mostraremos la íntima relación que con esta temática guardarían dos obras que no suelen asociarse al programa metafilosófico triasiano como son Filosofía y Carnaval (1970 (con su propuesta de la concepción de la identidad como profusión de máscaras y de la sociabilidad como Carnaval y La dispersión (1971 (desde su pensamiento fragmentario, aforístico. Ambas obras responderían a una misma estrategia caracterizada por el propio Trías de «mágica» y por nosotros (en un sentido que aclaramos al final del artículo de «cínica».

  9. β-TrCP1 Is a Vacillatory Regulator of Wnt Signaling.

    Science.gov (United States)

    Long, Marcus John; Lin, Hong-Yu; Parvez, Saba; Zhao, Yi; Poganik, Jesse Richard; Huang, Paul; Aye, Yimon

    2017-08-17

    Simultaneous hyperactivation of Wnt and antioxidant response (AR) are often observed during oncogenesis. However, it remains unclear how the β-catenin-driven Wnt and the Nrf2-driven AR mutually regulate each other. The situation is compounded because many players in these two pathways are redox sensors, rendering bolus redox signal-dosing methods uninformative. Herein we examine the ramifications of single-protein target-specific AR upregulation in various knockdown lines. Our data document that Nrf2/AR strongly inhibits β-catenin/Wnt. The magnitude and mechanism of this negative regulation are dependent on the direct interaction between β-catenin N terminus and β-TrCP1 (an antagonist of both Nrf2 and β-catenin), and independent of binding between Nrf2 and β-TrCP1. Intriguingly, β-catenin positively regulates AR. Because AR is a negative regulator of Wnt regardless of β-catenin N terminus, this switch of function is likely sufficient to establish a new Wnt/AR equilibrium during tumorigenesis. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Três comédias de Shakespeare pela ótica do Stablex

    Directory of Open Access Journals (Sweden)

    Marly Gondim Cavalcanti Souza

    2012-09-01

    Full Text Available http://dx.doi.org/10.5007/2176-8552.2011nesp1p119 Pretende-se, neste estudo, proceder a análise de três comédias de William Shakespeare, pela ótica do método de análise lexical, textual e discursiva, aplicando, especificamente, a ferramenta matemático-estatístico-computacional, denominada Stablex, de autoria de André Camlong e Thierry Beltran (2004.Toma-se como viés de análise o aspecto musical presente no texto das três peças teatrais. Metodologicamente, trilhou-se o caminho do estudo comparativo entre as obras shakespearianas, tendo como horizonte a colaboração da música na expressão verbal dos textos teatrais do autor inglês, com o intuito de localizar os vocabulários preferenciais e o peso dos itens lexicais relacionados à música, na obra do talvez mais famoso escritor de língua inglesa. O fundamento para as evidências musicais repousa sobre a teoria e a história da música, bem como nos seus elementos básicos. As teorias tomadas como alicerce deste estudo são as de: Jean-Louis Cupers (1988, Arroyas (2001, Solange Oliveira (2002, André Camlong (1996 e Steven Paul Scher (apud OLIVEIRA, 2002.

  11. Immortalization of chicken preadipocytes by retroviral transduction of chicken TERT and TR

    Science.gov (United States)

    Wang, Wei; Zhang, Tianmu; Wu, Chunyan; Wang, Shanshan; Wang, Yuxiang; Wang, Ning

    2017-01-01

    The chicken is an important agricultural animal and model for developmental biology, immunology and virology. Excess fat accumulation continues to be a serious problem for the chicken industry. However, chicken adipogenesis and obesity have not been well investigated, because no chicken preadipocyte cell lines have been generated thus far. Here, we successfully generated two immortalized chicken preadipocyte cell lines through transduction of either chicken telomerase reverse transcriptase (chTERT) alone or in combination with chicken telomerase RNA (chTR). Both of these cell lines have survived >100 population doublings in vitro, display high telomerase activity and have no sign of replicative senescence. Similar to primary chicken preadipocytes, these two cell lines display a fibroblast-like morphology, retain the capacity to differentiate into adipocytes, and do not display any signs of malignant transformation. Isoenzyme analysis and PCR-based analysis confirmed that these two cell lines are of chicken origin and are free from inter-species contamination. To our knowledge, this is the first report demonstrating the generation of immortal chicken cells by introduction of chTERT and chTR. Our established chicken preadipocyte cell lines show great promise as an in vitro model for the investigation of chicken adipogenesis, lipid metabolism, and obesity and its related diseases, and our results also provide clues for immortalizing other avian cell types. PMID:28486516

  12. TrES-5: A MASSIVE JUPITER-SIZED PLANET TRANSITING A COOL G DWARF

    International Nuclear Information System (INIS)

    Mandushev, Georgi; Dunham, Edward W.; Quinn, Samuel N.; Latham, David W.; Charbonneau, David; Buchhave, Lars A.; Rabus, Markus; Oetiker, Brian; Brown, Timothy M.; Belmonte, Juan A.; O'Donovan, Francis T.

    2011-01-01

    We report the discovery of TrES-5, a massive hot Jupiter that transits the star GSC 03949-00967 every 1.48 days. From spectroscopy of the star we estimate a stellar effective temperature of T eff = 5171 ± 36 K, and from high-precision B, R, and I photometry of the transit we constrain the ratio of the semimajor axis a and the stellar radius R * to be a/R * = 6.07 ± 0.14. We compare these values to model stellar isochrones to obtain a stellar mass of M * = 0.893 ± 0.024 M ☉ . Based on this estimate and the photometric time series, we constrain the stellar radius to be R * = 0.866 ± 0.013 R ☉ and the planet radius to be R p = 1.209 ± 0.021 R J . We model our radial-velocity data assuming a circular orbit and find a planetary mass of 1.778 ± 0.063 M J . Our radial-velocity observations rule out line-bisector variations that would indicate a specious detection resulting from a blend of an eclipsing binary system. TrES-5 orbits one of the faintest stars with transiting planets found to date from the ground and demonstrates that precise photometry and followup spectroscopy are possible, albeit challenging, even for such faint stars.

  13. Local mechanical and electromechanical properties of the P(VDF-TrFE)-graphene oxide thin films

    Science.gov (United States)

    Silibin, M. V.; Bystrov, V. S.; Karpinsky, D. V.; Nasani, N.; Goncalves, G.; Gavrilin, I. M.; Solnyshkin, A. V.; Marques, P. A. A. P.; Singh, Budhendra; Bdikin, I. K.

    2017-11-01

    Recently, many organic materials, including carbon materials such as carbon nanotubes (CNTs) and graphene (single-walled carbon sheet structure) were studied in order to improve their mechanical and electrical properties. In particular, copolymers of poly (vinylidene fluoride) and poly trifluoroethylene [P(VDF-TrFE)] are promising materials, which can be used as probes, sensors, actuators, etc. Composite thin film of the copolymer P(VDF-TrFE) with graphene oxide (GO) were prepared by spin coating. The obtained films were investigated using piezoresponse force microscopy (PFM). The switching behavior, piezoelectric response, dielectric permittivity and mechanical properties of the films were found to depend on the presence of GO. For understanding the mechanism of piezoresponse evolution of the composite we used models of PVDF chain, its behavior in electrical field and computed the data for piezoelectric coefficients using HyperChem software. The summarized models of graphene oxide based on graphene layer from 96 carbon atoms C: with oxygen and OH groups and with COOH groups arranged by hydrogen were used for PVDF/Graphene oxide complex: 1) with H-side (hydrogen atom) connected from PVDF to graphene oxide, 2) with F-side (fluorine atom) connected from PVDF graphene oxide and 3) Graphene Oxide/PVDF with both sides (sandwich type). Experimental results qualitatively correlate with those obtained in the calculations.

  14. A photometric analysis of the neglected EW-type binary V336 TrA

    Science.gov (United States)

    Kriwattanawong, W.; Sarotsakulchai, T.; Maungkorn, S.; Reichart, D. E.; Haislip, J. B.; Kouprianov, V. V.; LaCluyze, A. P.; Moore, J. P.

    2018-05-01

    This study presents an analysis of photometric light curves and absolute parameters for the EW-type binary V336 TrA. VRI imaging observations were taken in 2013 by using the robotic telescopes PROMPT 4 and PROMPT 5 at Cerro Tololo Inter-American Observatory (CTIO), Chile. The observed light curves were fitted by using the Wilson-Devinney method. The results showed that V336 TrA is a W-type contact binary with a mass ratio of q = 1.396. The binary is a weak contact system with a fill-out factor of f = 15.69%. The system contains components with masses of 0.653 M⊙ and 0.912 M⊙ for the hotter and the cooler, respectively. The location of the secondary (less massive) component on the log M - log L diagram was found to be near the TAMS. The component has evolved to be oversize and overluminous. The orbital angular momentum of the binary was found to be log Jo = 51.61 cgs, less than all detached systems for same mass. The system has undergone angular momentum and/or mass loss, during the binary evolution from the detached to contact system.

  15. Immortalization of chicken preadipocytes by retroviral transduction of chicken TERT and TR.

    Directory of Open Access Journals (Sweden)

    Wei Wang

    Full Text Available The chicken is an important agricultural animal and model for developmental biology, immunology and virology. Excess fat accumulation continues to be a serious problem for the chicken industry. However, chicken adipogenesis and obesity have not been well investigated, because no chicken preadipocyte cell lines have been generated thus far. Here, we successfully generated two immortalized chicken preadipocyte cell lines through transduction of either chicken telomerase reverse transcriptase (chTERT alone or in combination with chicken telomerase RNA (chTR. Both of these cell lines have survived >100 population doublings in vitro, display high telomerase activity and have no sign of replicative senescence. Similar to primary chicken preadipocytes, these two cell lines display a fibroblast-like morphology, retain the capacity to differentiate into adipocytes, and do not display any signs of malignant transformation. Isoenzyme analysis and PCR-based analysis confirmed that these two cell lines are of chicken origin and are free from inter-species contamination. To our knowledge, this is the first report demonstrating the generation of immortal chicken cells by introduction of chTERT and chTR. Our established chicken preadipocyte cell lines show great promise as an in vitro model for the investigation of chicken adipogenesis, lipid metabolism, and obesity and its related diseases, and our results also provide clues for immortalizing other avian cell types.

  16. Detection of fast oscillating magnetic fields using dynamic multiple TR imaging and Fourier analysis.

    Directory of Open Access Journals (Sweden)

    Ki Hwan Kim

    Full Text Available Neuronal oscillations produce oscillating magnetic fields. There have been trials to detect neuronal oscillations using MRI, but the detectability in in vivo is still in debate. Major obstacles to detecting neuronal oscillations are (i weak amplitudes, (ii fast oscillations, which are faster than MRI temporal resolution, and (iii random frequencies and on/off intervals. In this study, we proposed a new approach for direct detection of weak and fast oscillating magnetic fields. The approach consists of (i dynamic acquisitions using multiple times to repeats (TRs and (ii an expanded frequency spectral analysis. Gradient echo echo-planar imaging was used to test the feasibility of the proposed approach with a phantom generating oscillating magnetic fields with various frequencies and amplitudes and random on/off intervals. The results showed that the proposed approach could precisely detect the weak and fast oscillating magnetic fields with random frequencies and on/off intervals. Complex and phase spectra showed reliable signals, while no meaningful signals were observed in magnitude spectra. A two-TR approach provided an absolute frequency spectrum above Nyquist sampling frequency pixel by pixel with no a priori target frequency information. The proposed dynamic multiple-TR imaging and Fourier analysis are promising for direct detection of neuronal oscillations and potentially applicable to any pulse sequences.

  17. Sequential least-square reconstruction of instantaneous pressure field around a body from TR-PIV

    Science.gov (United States)

    Jeon, Young Jin; Gomit, G.; Earl, T.; Chatellier, L.; David, L.

    2018-02-01

    A procedure is introduced to obtain an instantaneous pressure field around a wing from time-resolved particle image velocimetry (TR-PIV) and particle image accelerometry (PIA). The instantaneous fields of velocity and material acceleration are provided by the recently introduced multi-frame PIV method, fluid trajectory evaluation based on ensemble-averaged cross-correlation (FTEE). The integration domain is divided into several subdomains in accordance with the local reliability. The near-edge and near-body regions are determined based on the recorded image of the wing. The instantaneous wake region is assigned by a combination of a self-defined criterion and binary morphological processes. The pressure is reconstructed from a minimization process of the difference between measured and reconstructed pressure gradients in a least-square sense. This is solved sequentially according to a decreasing order of reliability of each subdomain to prevent a propagation of error from the less reliable near-body region to the free-stream. The present procedure is numerically assessed by synthetically generated 2D particle images based on a numerical simulation. Volumetric pressure fields are then evaluated from tomographic TR-PIV of a flow around a 30-degree-inclined NACA0015 airfoil. A possibility of using a different scheme to evaluate material acceleration for a specific subdomain is presented. Moreover, this 3D application allows the investigation of the effect of the third component of the pressure gradient by which the wake region seems to be affected.

  18. Influência de três modos de fotopolimerização sobre a microdureza de três resinas compostas

    Directory of Open Access Journals (Sweden)

    Andréa Cristina Schneider

    2016-01-01

    Full Text Available Resumo A adequada fotopolimerização das resinas compostas é fundamental para obtenção de uma boa dureza capaz de resistir aos esforços mastigatórios. Assim, o objetivo deste estudo foi avaliar a influência das técnicas de fotopolimerização - Convencional (CONV, Soft-start (SS e Pulso atrasado (PA na microdureza Knoop de três resinas compostas. Para a confecção dos corpos-de-prova foram utilizadas as resinas compostas Filtek Z350 (3M ESPE, Empress Direct (IvoclarVivadent e P90 (3M ESPE. Foram obtidos nove grupos experimentais em função da técnica de polimerização e resina composta. Vinte e quatro horas após a fotopolimerização foi realizado o teste de microdureza Knoop nas superfícies de base e topo de cada corpo-de-prova. Assim, os valores obtidos foram submetidos ao teste de Kruskall Wallis, seguido do teste de Dunn, p < 0,05. A eficácia da polimerização na superfície de topo das resinas compostas testadas não foi afetada pelos diferentes modos de polimerização. A resina composta Empress Direct apresentou os mais baixos valores de dureza para todos os modos de polimerização quando comparada às demais resinas compostas avaliadas.

  19. Orphan nuclear receptor TR3/Nur77 improves wound healing by upregulating the expression of integrin β4.

    Science.gov (United States)

    Niu, Gengming; Ye, Taiyang; Qin, Liuliang; Bourbon, Pierre M; Chang, Cheng; Zhao, Shengqiang; Li, Yan; Zhou, Lei; Cui, Pengfei; Rabinovitz, Issac; Mercurio, Arthur M; Zhao, Dezheng; Zeng, Huiyan

    2015-01-01

    Tissue repair/wound healing, in which angiogenesis plays an important role, is a critical step in many diseases including chronic wound, myocardial infarction, stroke, cancer, and inflammation. Recently, we were the first to report that orphan nuclear receptor TR3/Nur77 is a critical mediator of angiogenesis and its associated microvessel permeability. Tumor growth and angiogenesis induced by VEGF-A, histamine, and serotonin are almost completely inhibited in Nur77 knockout mice. However, it is not known whether TR3/Nur77 plays any roles in wound healing. In these studies, skin wound-healing assay was performed in 3 types of genetically modified mice having various Nur77 activities. We found that ectopic induction of Nur77 in endothelial cells of mice is sufficient to improve skin wound healing. Although skin wound healing in Nur77 knockout mice is comparable to the wild-type control mice, the process is significantly delayed in the EC-Nur77-DN mice, in which a dominant negative Nur77 mutant is inducibly and specifically expressed in mouse endothelial cells. By a loss-of-function assay, we elucidate a novel feed-forward signaling pathway, integrin β4 → PI3K → Akt → FAK, by which TR3 mediates HUVEC migration. Furthermore, TR3/Nur77 regulates the expression of integrin β4 by targeting its promoter activity. In conclusion, expression of TR3/Nur77 improves wound healing by targeting integrin β4. TR3/Nur77 is a potential candidate for proangiogenic therapy. The results further suggest that TR3/Nur77 is required for pathologic angiogenesis but not for developmental/physiologic angiogenesis and that Nur77 and its family members play a redundant role in normal skin wound healing. © FASEB.

  20. O enfrentamento ao tráfico de pessoas no âmbito do Mercosul

    Directory of Open Access Journals (Sweden)

    Mário Lúcio Quintão Soares

    2011-12-01

    Full Text Available Human trafficking is a serious problemthat, in its various forms – sexual exploitation,forced labor and removal of organs – isin the form of transnational organized crime,affecting every country in the world. Apparently,the increasing political integration, economicand social activity is one way to attempt to minimizethe human trafficking. In the case of theSouthern Cone Common Market – Mercosur,efforts have been made to both by its States Parties(Argentina, Brazil, Paraguay and Uruguay,as they ratified the Palermo Protocol. Within thisframework, this study aimed to examine the measuresadopted within Mercosur in a way to protectand promote the rights of trafficked persons.To accomplish this work, the emphasis has beendescriptive and analytical study, by means of literatureand documents. Note that only Brazil andArgentina have adopted specific policies on traffickingin persons. Given this, it was found thatthe States Parties of Mercosur develop actions toprotect and promote human rights of traffickedpersons, not counting even some specific publicpolicy.O tráfico de pessoas é um problema graveque, nas suas diversas modalidades – exploraçãosexual, trabalhos forçados e remoção de órgãos –constitui-se em forma de crime organizado transnacional,atingindo todos os países do mundo. Ao queparece, a crescente integração política, econômica esocial constitui caminho para uma tentativa de minimizaçãodo tráfico de pessoas. Em se tratando deMercado Comum do Cone Sul – Mercosul, esforçostêm sido envidados para tanto por parte dos seus EstadosPartes (Argentina, Brasil, Paraguai e Uruguai,pois esses países ratificaram o Protocolo de Palermo.Nesse marco, esta pesquisa teve por objetivo analisaras medidas adotadas no âmbito do Mercosul para aproteção e promoção dos direitos das pessoas traficadas.Para a concretização deste trabalho, privilegiou-se o estudo descritivo e analítico, por meio depesquisa bibliográfica e

  1. Theoretical-Numerical Analysis of Boundary-Layer Stability with Combined Injection and Acoustic Absorptive Coating

    Science.gov (United States)

    2014-01-01

    relaxation region is higher than the critical trN N= , the transition onset point trx is predicted to be close to the injector. Decreasing of m weakly...affects trx until maxN becomes lower than trN . At this moment the transition point jumps to the x -station, which may be even downstream from

  2. Novel treatment option for MUC16-positive malignancies with the targeted TRAIL-based fusion protein Meso-TR3

    International Nuclear Information System (INIS)

    Garg, Gunjal; Spitzer, Dirk; Gibbs, Jesse; Belt, Brian; Powell, Matthew A; Mutch, David G; Goedegebuure, Peter; Collins, Lynne; Piwnica-Worms, David; Hawkins, William G

    2014-01-01

    The targeted delivery of cancer therapeutics represents an ongoing challenge in the field of drug development. TRAIL is a promising cancer drug but its activity profile could benefit from a cancer-selective delivery mechanism, which would reduce potential side effects and increase treatment efficiencies. We recently developed the novel TRAIL-based drug platform TR3, a genetically fused trimer with the capacity for further molecular modifications such as the addition of tumor-directed targeting moieties. MUC16 (CA125) is a well characterized biomarker in several human malignancies including ovarian, pancreatic and breast cancer. Mesothelin is known to interact with MUC16 with high affinity. In order to deliver TR3 selectively to MUC16-expressing cancers, we investigated the possibility of targeted TR3 delivery employing the high affinity mesothelin/MUC16 ligand/receptor interaction. Using genetic engineering, we designed the novel cancer drug Meso-TR3, a fusion protein between native mesothelin and TR3. The recombinant proteins were produced with mammalian HEK293T cells. Meso-TR3 was characterized for binding selectivity and killing efficacy against MUC16-positive cancer cells and controls that lack MUC16 expression. Drug efficacy experiments were performed in vitro and in vivo employing an intraperitoneal xenograft mouse model of ovarian cancer. Similar to soluble mesothelin itself, the strong MUC16 binding property was retained in the Meso-TR3 fusion protein. The high affinity ligand/receptor interaction was associated with a selective accumulation of the cancer drug on MUC16-expressing cancer targets and directly correlated with increased killing activity in vitro and in a xenograft mouse model of ovarian cancer. The relevance of the mesothelin/MUC16 interaction for attaching Meso-TR3 to the cancer cells was verified by competitive blocking experiments using soluble mesothelin. Mechanistic studies using soluble DR5-Fc and caspase blocking assays confirmed

  3. Características entonacionais do Espanhol na Tríplice Fronteira

    OpenAIRE

    Figueiredo, Natalia dos Santos; Gil Mondavi, Alejandro Said; Guerra, Paula Marianela

    2014-01-01

    XVII CONGRESO INTERNACIONAL ASOCIACIÓN DE LINGÜÍSTICA Y FILOLOGÍA DE AMÉRICA LATINA (ALFAL 2014) João Pessoa - Paraíba, Brasil O objetivo desse trabalho é realizar uma análise fonética e fonológica de variedades entonacionais do espanhol encontradas na Tríplice Fronteira, especificamente nas cidades de Puerto Iguazú e Ciudad del Este, que fazem fronteira com a cidade de Foz do Iguaçu. Para esse fim, foram gravadas diversas situações de pedidos de ação em contextos de comércio e...

  4. Core-free rolled actuators for Braille displays using P(VDF-TrFE-CFE)

    Science.gov (United States)

    Levard, Thomas; Diglio, Paul J.; Lu, Sheng-Guo; Rahn, Christopher D.; Zhang, Q. M.

    2012-01-01

    Refreshable Braille displays require many small diameter actuators to move the pins. The electrostrictive P(VDF-TrFE-CFE) terpolymer can provide the high strain and actuation force under modest electric fields that are required for this application. In this paper, we develop core-free tubular actuators and integrate them into a 3 × 2 Braille cell. The terpolymer films are solution cast, stretched to 6 μm thick, electroded, laminated into a bilayer, rolled into a 2 mm diameter tube, bonded, and provided with top and bottom contacts. Experimental testing of 17 actuators demonstrates significant strains (up to 4%) and blocking forces (1 N) at moderate electric fields (100 MV m-1). A novel Braille cell is designed and fabricated using six of these actuators.

  5. Core-free rolled actuators for Braille displays using P(VDF–TrFE–CFE)

    International Nuclear Information System (INIS)

    Levard, Thomas; Diglio, Paul J; Rahn, Christopher D; Lu, Sheng-Guo; Zhang, Q M

    2012-01-01

    Refreshable Braille displays require many small diameter actuators to move the pins. The electrostrictive P(VDF–TrFE–CFE) terpolymer can provide the high strain and actuation force under modest electric fields that are required for this application. In this paper, we develop core-free tubular actuators and integrate them into a 3 × 2 Braille cell. The terpolymer films are solution cast, stretched to 6 μm thick, electroded, laminated into a bilayer, rolled into a 2 mm diameter tube, bonded, and provided with top and bottom contacts. Experimental testing of 17 actuators demonstrates significant strains (up to 4%) and blocking forces (1 N) at moderate electric fields (100 MV m −1 ). A novel Braille cell is designed and fabricated using six of these actuators. (fast track communication)

  6. Klippel–Trénaunay Syndrome – A Very Rare and Interesting Syndrome

    Directory of Open Access Journals (Sweden)

    Deepak Sharma

    2015-01-01

    Full Text Available Klippel–Trénaunay syndrome (KTS or KT is an infrequently seen dermatological syndrome, which is often viewed as a triad of vascular malformation (capillary malformations or port-wine brands, venous varicosity, and soft tissue and/or bony hypertrophy. We report a case of a 12-year-old male who presented to us with the symptoms of varicose plaques over both lower limbs and was diagnosed as a case of KTS. Management is normally conservative and includes stockings for compression of the branches to reduce edema because of chronic venous insufficiency; modern devices that cause on and off pneumatic compression; and rarely, surgical correction of varicose veins with lifelong follow-up. The orthopedic abnormalities are treated with epiphysiodesis in order to prevent (stop overgrowing of limb and correction of bone deformity.

  7. Vandenilio kuro elementų tyrimas srovės trūkio metodu

    OpenAIRE

    Tamošaitis, Kęstutis

    2011-01-01

    Bakalauro baigiamąjį darbą „ Vandenilio kuro elementų tyrimas srovės trūkio metodu“ sudaro 5 skyriai: įvadas, teorinė dalis, tyrimų dalis, išvados, literatūra ir priedai. Darbo apimtį sudaro 73 puslapiai, 69 paveikslėliai, 3 lentelės ir 4 priedai. Darbe aprašomos įvairių tipų kuro elementai, jų veikimas. Nagrinėjama PEM kuro elemento veikimo principai. Pateikti PEM kuro elemento savybių eksperimentinio tyrimo rezultatai. The final work for bachelors degree „Investigation of Fuel Cells by C...

  8. O processo das soluções brasileiras no exemplo do tráfico negreiro

    Directory of Open Access Journals (Sweden)

    Luís Henrique Dias Tavares

    1967-12-01

    Full Text Available O Brasil esteve solucionando o grave problema do trafico negreiro de, pelo menos, 1815 a 1854. Ou seja: do Tratado que Portugal assinou com a Inglaterra em janeiro de 1815, às medidas práticas que o Brasil adotou em decorrência da Lei anti-tráfico de 1850. Nesse decurso de trinta e nove anos, largos e puxados trinta e nove anos, o jovem Brasil passou da condição de Colônia para a de país livre, o seu regime monárquico constitucional experimentou os arrancos e desequilíbrios da deposição de Pedro I, das Regências Trinas e Unas, dos vários movimentos federalistas, das muitas insurreições de escravos e do golpe de Estado que antecedeu a entrega do Trono ao pequeno príncipe D . Pedro.

  9. Perspectivas de género en las condenas por tráfico de drogas

    Directory of Open Access Journals (Sweden)

    Luz M. Puente Aba

    2012-12-01

    Full Text Available This article pretends to examine sentences for drug trafficking from a gender perspective. An in-depth analysis of sentences and prison statistics from this point of view reveals that women are most affected by this repressive policy. The most remarkable fact is that while the number of convicted women in general is low, a large percentage of female offenders’ sentences are related to drug offences, thus representing a higher percentage in this group than in the male group. Yet if we analyze the prison population from a gender perspective, the results are even more striking: whereas women make up an insignificant percentage of the total, they nonetheless represent a large part of the total number of sentences for drug trafficking. Furthermore, a study of the characteristics of women sentenced for these crimes allows us to trace a specific profile for this group, which in turn provides an insight into why women are the main victims of the repressive drug policy, and the consequences they face. It will be analyzed whether penal treatment contributes to an excessive representation of the feminine gender in prisons; which gender sectors are particularly affected; and how we could find the causes and consequences of this situation. To conclude, new ways to solve this problem are suggested: reconsidering criminal policy on drugs, or strengthening alternatives to prison and different measures to support people serving sentences in prison. Este trabajo pretende analizar las condenas por tráfico de drogas desde una perspectiva de género. Partiendo de las estadísticas relativas al número y tipología de condenas por delitos, y asimismo de las estadísticas relativas a la población de los centros penitenciarios, se puede extraer que las mujeres son las más afectadas por la política penal en materia de tráfico de drogas, de carácter marcadamente represivo, puesto que suponen un porcentaje ínfimo de la población penitenciaria, y en cambio

  10. Nouveautés sur le rétrécissement valvulaire aortique

    OpenAIRE

    Pibarot, Philippe; Dumesnil, Jean G.; Mathieu, Patrick

    2007-01-01

    En Occident, le rétrécissement aortique (RA) est la maladie cardiovasculaire la plus fréquente après la maladie coronarienne et l’hypertension artérielle. La cause la plus fréquente de cette pathologie est le RA dégénératif dont le vieillissement a longtemps été considéré comme la cause inéluctable. Des données récentes suggèrent cependant que le RA serait une maladie active présentant de nombreuses similitudes avec l’athérosclérose et, de ce fait, susceptible d’être traitée grâce à des chang...

  11. Sistemas agrosilvopastoriles: una alternativa de desarrollo rural sustentable para el trópico mexicano

    Directory of Open Access Journals (Sweden)

    M. Á. Musálem

    2002-01-01

    Full Text Available Se presenta algunas definiciones de agroforestería, los conceptos y características y la importancia y perspectivas en México. Además, se describe brevemente algunos de los sistemas más importantes en las regiones templadas, tropicales y áridas de México. Así mismo, se ejemplifica con algunos esquemas producto de la investigación reciente aplicados en la región tropical de Puebla y Veracruz y en la zona templada del Estado de México. Así mismo, se enfatiza la aplicación de los sistemas agrosilvopastoriles en las fincas de los pequeños productores en el trópico de México.

  12. Sensitivity of diamond-capped impedance transducer to Tröger's base derivative.

    Science.gov (United States)

    Stehlik, Stepan; Izak, Tibor; Kromka, Alexander; Dolenský, Bohumil; Havlík, Martin; Rezek, Bohuslav

    2012-08-01

    Sensitivity of an intrinsic nanocrystalline diamond (NCD) layer to naphthalene Tröger's base derivative decorated with pyrrole groups (TBPyr) was characterized by impedance spectroscopy. The transducer was made of Au interdigitated electrodes (IDE) with 50 μm spacing on alumina substrate which were capped with the NCD layer. The NCD-capped transducer with H-termination was able to electrically distinguish TBPyr molecules (the change of surface resistance within 30-60 kΩ) adsorbed from methanol in concentrations of 0.04 mg/mL to 40 mg/mL. An exponential decay of the surface resistance with time was observed and attributed to the readsorption of air moisture after methanol evaporation. After surface oxidation the NCD cap layer did not show any leakage due to NCD grain boundaries. We analyzed electronic transport in the transducer and propose a model for the sensing mechanism based on surface ion replacement.

  13. Dose assessment around TR-2 reactor due to maximum credible accident

    International Nuclear Information System (INIS)

    Turgut, M. H.; Adalioglu, U.; Aytekin, A.

    2001-01-01

    The revision of safety analysis report of TR-2 research reactor had been initiated in 1995. The whole accident analysis and accepted scenario for maximum credible accident has been revised according to the new safety concepts and the impact to be given to the environment due to this scenario has been assessed. This paper comprises all results of these calculations. The accepted maximum credible accident scenario is the partial blockage of the whole reactor core which resulted in the release of 25% of the core inventory. The DOSER code which uses very conservative modelling of atmospheric distributions were modified for the assessment calculations. Pasquill conditions based on the local weather observations, topography, and building affects were considered. The thyroid and whole body doses for 16 sectors and up to 10 km of distance around CNAEM were obtained. Release models were puff and a prolonged one of two hours of duration. Release fractions for the active isotopes were chosen from literature which were realistic

  14. A TR-UWB Downconversion Autocorrelation Receiver for Wireless Body Area Network

    Directory of Open Access Journals (Sweden)

    Islam SMRiazul

    2009-01-01

    Full Text Available Low power UWB receiver architecture is proposed for a Wireless Body Area Network (WBAN. This receiving technology is a synergy of existing downconversion-based narrowband rejection mechanism in RF front end and signal processing in frequency domain. Frequency components of converted and filtered UWB pulses are separated into real and imaginary parts, independently correlated and effectively combined to achieve an improved output Signal to noise ratio (SNR. An extensive mathematical analysis has been performed to formulate the close-form expressions for SNRs in order to compare system performances toward favorable BER under BPSK modulation scheme. Analysis shows that optimal rotation of coordination plays an important role for the enhancement of receiving SNR which is further confirmed by computer simulation. A wide range of link level simulation (LLS urges that the proposed system is more power efficient in higher-order modulation (HOM schemes. Transmitted Reference (TR scheme has been considered as the basis for wideband communication.

  15. Flow field characteristics of impinging sweeping jets: TR-PIV measurement

    Science.gov (United States)

    Wen, Xin; Peng, Di; Liu, Yingzheng; Tang, Hui

    2017-11-01

    Influence of Reynolds number of sweeping jets on its impinging flow fields was extensively investigated in a water tank. Toward this end, a fluidic oscillator was specially designed to produce spatially sweeping jets which imping on a flat plate. Six Reynolds numbers were tested by controlling the supply flow rate of the fluidic oscillator. Impinging flow fields were captured by time-resolved Particle Image Velocimetry (TR-PIV) measurement. Reference signals were extracted from the flow fields for phase reconstruction. The oscillating flow fields with super-harmonic frequency at different regions were discussed in term of the phase-averaged velocity, vorticity and turbulent velocity. Dynamic mode decomposition (DMD) was used to capture the most-energetic flow patterns with distinct frequencies. By projecting the phase-averaged flow fields onto a reduced basis of DMD modes, the phase correlation between the distinct flow patterns were analyzed under different Reynolds numbers.

  16. Modelo ARIMA para pronosticar valores de tráfico en una red de datos Wi-Fi

    Directory of Open Access Journals (Sweden)

    Cesar Augusto Hernández Suarez

    2009-05-01

    Full Text Available El presente artículo de investigación científica y tecnológica tiene por objetivo demostrar que las series de tiempo son una exce- lente herramienta para el modelamiento de tráfico de datos en redes Wi-Fi. Para lograr este objetivo se utilizó la metodología de Box-Jenkins, la cual se describe. El modelamiento de tráfico Wi-Fi a través de modelos correlacionados como las series de tiem- po, permiten ajustar gran parte de la dinámica del comportamiento de los datos en una ecuación y con base en esto estimar va- lores futuros de tráfico. Lo anterior es una ventaja para la planeación de cobertura, reservación de recursos y la realización de un control más oportuno y eficiente en forma integrada a diferentes niveles de la jerarquía funcional de la red de datos Wi-Fi. Como resultado de la investigación se obtuvo un modelo de tráfico ARIMA de orden 6, el cual realizó pronósticos de tráfico con valores del error cuadrático medio relativamente pequeños, para un periodo de 18 días.

  17. T-R CYCLE CHARACTERIZATION AND IMAGING: ADVANCED DIAGNOSTIC METHODOLOGY FOR PETROLEUM RESERVOIR AND TRAP DETECTION AND DELINEATION

    Energy Technology Data Exchange (ETDEWEB)

    Ernest A. Mancini

    2004-09-24

    The principal research effort for Year 1 of the project has been T-R cycle characterization and modeling. The research focus for the first nine (9) months of Year 1 was on outcrop study, well log analysis, seismic interpretation and data integration and for the remainder of the year the emphasis has been on T-R cycle model development. Information regarding the characteristics of T-R cycles has been assembled from the study of outcrops, from well log analyses, and from seismic reflection interpretation. From these studies, stratal boundaries separating T-R cycles have been found to be useful for the recognition and delineation of these cycles. The key stratal surfaces include subaerial unconformities, shoreface ravinement surfaces, transgressive surfaces, surfaces of maximum regression, and surfaces of maximum transgression. These surfaces can be identified and mapped in surface exposures and can be recognized in well log signatures and seismic reflection profiles as discontinuities. The findings from the study of outcrop, well log, and seismic reflection data are being integrated into a database for use in constructing a model for T-R cycle development.

  18. beta-TrCP inhibition reduces prostate cancer cell growth via upregulation of the aryl hydrocarbon receptor.

    Directory of Open Access Journals (Sweden)

    Udi Gluschnaider

    2010-02-01

    Full Text Available Prostate cancer is a common and heterogeneous disease, where androgen receptor (AR signaling plays a pivotal role in development and progression. The initial treatment for advanced prostate cancer is suppression of androgen signaling. Later on, essentially all patients develop an androgen independent stage which does not respond to anti hormonal treatment. Thus, alternative strategies targeting novel molecular mechanisms are required. beta-TrCP is an E3 ligase that targets various substrates essential for many aspects of tumorigenesis.Here we show that beta-TrCP depletion suppresses prostate cancer and identify a relevant growth control mechanism. shRNA targeted against beta-TrCP reduced prostate cancer cell growth and cooperated with androgen ablation in vitro and in vivo. We found that beta-TrCP inhibition leads to upregulation of the aryl hydrocarbon receptor (AhR mediating the therapeutic effect. This phenomenon could be ligand independent, as the AhR ligand 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD did not alter prostate cancer cell growth. We detected high AhR expression and activation in basal cells and atrophic epithelial cells of human cancer bearing prostates. AhR expression and activation is also significantly higher in tumor cells compared to benign glandular epithelium.Together these observations suggest that AhR activation may be a cancer counteracting mechanism in the prostate. We maintain that combining beta-TrCP inhibition with androgen ablation could benefit advanced prostate cancer patients.

  19. Assessment of documentation of DSM-IV-TR Criteria A for diagnosis of schizophrenia in psychiatric unit, tertiary hospital, Malaysia.

    Science.gov (United States)

    Maung, K; Ohnmar, H; Than, W; Ramli, M; Najwa Hanim, M R; Ali Sabri, R; Ahmad Zafri, A B

    The purposes of this study were to investigate the documentation of the DSM-IV-TR- Criteria A in diagnoses of schizophrenia and to identify the symptoms associated with over diagnosis of schizophrenia. This study involved a retrospective review and analysis of data from case notes. Data of 107 newly diagnosed patients with schizophrenia were keyed in and analyzed using SPSS v 19. The cases were then evaluated for the use of the DSM-IV-TR- Criteria A. Over diagnosis was noted in 37.39% of the patients. Disorganised behaviour (12.5%), affective flattening (12.5%), hallucination (16%) and non-bizarre delusion (18.3%) significantly contributed to the over-diagnosis of schizophrenia. Symptoms such as non-bizarre delusion and hallucination were the most commonly used in over-diagnosing schizophrenia and were statistically significant with p ≤0.05. There was a significant lack of DSM-IV-TR Criteria A among the data documented to diagnose schizophrenia and non-bizarre delusion and hallucination were the most commonly used in over-diagnosing schizophrenia. This key problem needs to be addressed. The reliability of a diagnosis is indispensable and achievable with the proper clinical application of DSM-IV-TR Criteria A. The DSM-IV-TR Criteria have been perceived to be useful and reliable and is most widely used throughout the world.

  20. Kliniske retningslinjer for træning af aerob kapacitet og muskelstyrke til patienter med reumatoid artrit

    DEFF Research Database (Denmark)

    Larsen, Birgit Tine; Læssøe, Uffe; Kjær, Thomas

    forstærker denne risiko. Formål: Gennem effektiv og sikker træning at øge RA patienters aerob kapacitet og muskel styrke for dermed atlette patienternes daglige aktiviteter. Patienter: Voksne patienter (> 18 år) med diagnosen reumatoid artrit ifølge ARA eller ACR/EULAR kriterierne,funktionsklasserne I, II og...... III, i primær eller sekundær sektoren. Intervention/er: Kortvarig land- eller vandbaseret højintensitets træning af aerob kapacitet, kortvarig eller længerevarendeland-baseret høj-intensitets træning af aerob kapacitet i kombination med muskelstyrke træning oglængerevarende land-baseret høj......-intensitets styrke træning. Inkluderet studier: Èt systematisk review og to randomiseret klinisk kontrolleret studier (RCT). Outcomes: Aerob kapacitet, maksimal muskelstyrke, selv-rapporteret smerte, funktionsevne, sygdomsaktivitet,radiologisk ledskade og uønskede bivirkninger. Søgestrategi:Følgende databaser blev...

  1. TrOn: an anatomical ontology for the beetle Tribolium castaneum.

    Directory of Open Access Journals (Sweden)

    Jürgen Dönitz

    Full Text Available In a morphological ontology the expert's knowledge is represented in terms, which describe morphological structures and how these structures relate to each other. With the assistance of ontologies this expert knowledge is made processable by machines, through a formal and standardized representation of terms and their relations to each other. The red flour beetle Tribolium castaneum, a representative of the most species rich animal taxon on earth (the Coleoptera, is an emerging model organism for development, evolution, physiology, and pest control. In order to foster Tribolium research, we have initiated the Tribolium Ontology (TrOn, which describes the morphology of the red flour beetle. The content of this ontology comprises so far most external morphological structures as well as some internal ones. All modeled structures are consistently annotated for the developmental stages larva, pupa and adult. In TrOn all terms are grouped into three categories: Generic terms represent morphological structures, which are independent of a developmental stage. In contrast, downstream of such terms are concrete terms which stand for a dissectible structure of a beetle at a specific life stage. Finally, there are mixed terms describing structures that are only found at one developmental stage. These terms combine the characteristics of generic and concrete terms with features of both. These annotation principles take into account the changing morphology of the beetle during development and provide generic terms to be used in applications or for cross linking with other ontologies and data resources. We use the ontology for implementing an intuitive search function at the electronic iBeetle-Base, which stores morphological defects found in a genome wide RNA interference (RNAi screen. The ontology is available for download at http://ibeetle-base.uni-goettingen.de.

  2. TrOn: an anatomical ontology for the beetle Tribolium castaneum.

    Science.gov (United States)

    Dönitz, Jürgen; Grossmann, Daniela; Schild, Inga; Schmitt-Engel, Christian; Bradler, Sven; Prpic, Nikola-Michael; Bucher, Gregor

    2013-01-01

    In a morphological ontology the expert's knowledge is represented in terms, which describe morphological structures and how these structures relate to each other. With the assistance of ontologies this expert knowledge is made processable by machines, through a formal and standardized representation of terms and their relations to each other. The red flour beetle Tribolium castaneum, a representative of the most species rich animal taxon on earth (the Coleoptera), is an emerging model organism for development, evolution, physiology, and pest control. In order to foster Tribolium research, we have initiated the Tribolium Ontology (TrOn), which describes the morphology of the red flour beetle. The content of this ontology comprises so far most external morphological structures as well as some internal ones. All modeled structures are consistently annotated for the developmental stages larva, pupa and adult. In TrOn all terms are grouped into three categories: Generic terms represent morphological structures, which are independent of a developmental stage. In contrast, downstream of such terms are concrete terms which stand for a dissectible structure of a beetle at a specific life stage. Finally, there are mixed terms describing structures that are only found at one developmental stage. These terms combine the characteristics of generic and concrete terms with features of both. These annotation principles take into account the changing morphology of the beetle during development and provide generic terms to be used in applications or for cross linking with other ontologies and data resources. We use the ontology for implementing an intuitive search function at the electronic iBeetle-Base, which stores morphological defects found in a genome wide RNA interference (RNAi) screen. The ontology is available for download at http://ibeetle-base.uni-goettingen.de.

  3. O mapa íntimo: três telas de Frida Kahlo Frida Kahlo's intimate map

    Directory of Open Access Journals (Sweden)

    Fabiano Seixas Fernandes

    2008-04-01

    Full Text Available O artigo apresenta análises de três telas da pintora mexicana Frida Kahlo - Las dos Fridas, Autorretrato en la frontera entre México y Estados Unidos e Lo que el agua me dio - e está dividido em três partes, cada qual tratando de uma tela em particular, para, no momento seguinte, ligar seu estudo ao das demais. Norteia a leitura das primeiras a discussão da relação nacional/estrangeiro no trabalho de Kahlo; a análise da terceira mostra a superação da dicotomia através do conceito de mapa íntimo, no qual entra em cena uma tênue e instável territorialização da memória através da representação pictórica.This article analyses three works by Mexican painter Frida Kahlo: Las dos Fridas (The Two Fridas, Autorretrato en la frontera entre México y Estados Unidos (Self-Portrait on the Borderline between Mexico and the United States, and Lo que el agua me dio (What the Water Gave Me. Each work is first analyzed separately and then connected with the others. The analysis of the first two is guided by the national/foreign dichotomy present in Kahlo; the analysis of the third shows the overcoming of the dichotomy through the concept of intimate map - in which a feeble and ever-changing territorialization of memory via plastic expression comes to show.

  4. Potencial discriminatório de três testadores em "topcrosses" de milho

    Directory of Open Access Journals (Sweden)

    Duarte Iran de Azevedo

    2003-01-01

    Full Text Available O objetivo deste trabalho foi determinar o potencial de três testadores endogâmicos elites a fim de avaliar e classificar 15 materiais genéticos para a síntese de híbridos. Quarenta e cinco híbridos mais quatro testemunhas foram avaliados em cinco ambientes, no ano agrícola 2000/2001, utilizando delineamento em blocos ao acaso, com três repetições. Foram avaliados os caracteres peso de grãos corrigido, altura de planta e altura de espiga. As estimativas de capacidade geral e específica de combinação foram obtidas pelo modelo de Griffing, adaptado por Vencovsky e Barriga, para análise em delineamento genético fatorial. O rendimento médio obtido entre os cinco ambientes variou de 8,97 t ha-1 a 12,21 t ha-1. Vinte e sete tratamentos superaram a média geral absoluta da melhor testemunha. A análise de variância conjunta revelou efeitos significativos de ambientes, capacidade geral de combinação dos parentais e testadores, capacidade específica de combinação e das interações ambiente x capacidade geral de combinação dos parentais e testadores. Os testadores promoveram uma classificação diferenciada para a base genética avaliada, com destaque para os cruzamentos entre parentais HS1, HS2, HS5 e HT4 com o testador LF e parentais L10 e HS5 com o testador L05.

  5. Why live recording sounds better: A case study of Schumann’s Träumerei

    Directory of Open Access Journals (Sweden)

    Haruka eShoda

    2015-01-01

    Full Text Available We explore the concept that artists perform best in front of an audience. The negative effects of performance anxiety are much better known than their related cousin on the other shoulder: the positive effects of social facilitation. The present study, however, reveals a listener's preference for performances recorded in front of an audience. In Study 1, we prepared two types of recordings of Träumerei performed by 13 pianists: recordings in front of an audience and those with no audience. According to the evaluation by 153 listeners, the recordings performed in front of an audience sounded better, suggesting that the presence of an audience enhanced or facilitated the performance. In Study 2, we analyzed pianists' durational and dynamic expressions. According to the functional principal components analyses, we found that the expression of Träumerei consisted of three components: the overall quantity, the cross-sectional contrast between the final and the remaining sections, and the control of the expressive variability. Pianists' expressions were targeted more to the average of the cross-sectional variation in the audience-present than in the audience-absent recordings. In Study 3, we explored a model that explained listeners' responses induced by pianists' acoustical expressions, using path analyses. The final model indicated that the cross-sectional variation of the duration and that of the dynamics determined listeners' evaluations of the quality and the emotionally moving experience, respectively. In line with human's preferences for commonality, the more average the durational expressions were in live recording, the better the listeners' evaluations were regardless of their musical experiences. Only the well-experienced listeners (at least 16 years of musical training were moved more by the deviated dynamic expressions in live recording, suggesting a link between the experienced listener's emotional experience and the unique dynamics in

  6. Evolução dos acidentes de trânsito em um grande centro urbano, 1991-2000

    OpenAIRE

    Oliveira, Zenaide Calazans de; Mota, Eduardo Luiz Andrade; Costa, Maria da Conceição Nascimento

    2008-01-01

    p. 364-372, fev, 2008 Este estudo descreve a evolução dos acidentes de trânsito Salvador, Bahia, Brasil, entre 1991 e 2000, utilizando- se dados do Departamento Estadual de Trânsito do Estado da Bahia. Calculou-se taxas globais dos acidentes de trânsito, vítimas e taxas padronizadas de mortalidade por habitante e por veículos, e comparou-se médias destes indicadores para antes (1991 a 1994) e após (1995 a 2000) a adoção de medidas de intervenção como o uso do cinto de segurança e o Código ...

  7. [Forensic assessment of DSM-5 posttraumatic stress disorder: a commentary on the transition from DSM-IV-TR (I)].

    Science.gov (United States)

    Stevens, A; Fabra, M

    2013-12-01

    In May 2013 the American Psychiatric Association (APA) has released the latest and fifth edition of the diagnostic and statistical manual of mental disorders (DSM-5). Like its predecessor, the DSM-IV-TR, it will have considerable impact on the science of Psychiatry. The DSM-5 describes - actually available in English - the present medical knowledge about mental disorders. In the short run, German medical science and scientific medicolegal expertises will continue to rely on the German version of the DSM-IV-TR, however, they will be difficult to defend without bearing in mind the changes that DSM-5 brings about. This report discusses the transition from DSM-IV-TR to DSM-5 with regard to posttraumatic stress disorder (PTSD) and provides suggestions, how the criteria might be evaluated.

  8. A tríade “Verdadeiro-Bom-Belo”: O lugar da beleza na Idade Média

    Directory of Open Access Journals (Sweden)

    Jan A. Aertsen

    2008-06-01

    Full Text Available Neste artigo, Jan Aertsen discute a compreensão da tríade “Verdadeiro-Belo-Bom” como representante de um conjunto de questões clássicas em filosofia, a qual corresponderia, do ponto de vista moderno, à suposição de que o sujeito possui três modos distintos de se relacionar com o mundo: cognitivo, estético e prático. O autor sugere que a tríade foi formulada explicitamente pela primeira vez na Idade Média; neste período, entretanto, a beleza não era considerada um problema “estético”.

  9. Data model and relational database design for the New Jersey Water-Transfer Data System (NJWaTr)

    Science.gov (United States)

    Tessler, Steven

    2003-01-01

    The New Jersey Water-Transfer Data System (NJWaTr) is a database design for the storage and retrieval of water-use data. NJWaTr can manage data encompassing many facets of water use, including (1) the tracking of various types of water-use activities (withdrawals, returns, transfers, distributions, consumptive-use, wastewater collection, and treatment); (2) the storage of descriptions, classifications and locations of places and organizations involved in water-use activities; (3) the storage of details about measured or estimated volumes of water associated with water-use activities; and (4) the storage of information about data sources and water resources associated with water use. In NJWaTr, each water transfer occurs unidirectionally between two site objects, and the sites and conveyances form a water network. The core entities in the NJWaTr model are site, conveyance, transfer/volume, location, and owner. Other important entities include water resource (used for withdrawals and returns), data source, permit, and alias. Multiple water-exchange estimates based on different methods or data sources can be stored for individual transfers. Storage of user-defined details is accommodated for several of the main entities. Many tables contain classification terms to facilitate the detailed description of data items and can be used for routine or custom data summarization. NJWaTr accommodates single-user and aggregate-user water-use data, can be used for large or small water-network projects, and is available as a stand-alone Microsoft? Access database. Data stored in the NJWaTr structure can be retrieved in user-defined combinations to serve visualization and analytical applications. Users can customize and extend the database, link it to other databases, or implement the design in other relational database applications.

  10. Autism spectrum disorders according to DSM-IV-TR and comparison with DSM-5 draft criteria: an epidemiological study.

    Science.gov (United States)

    Mattila, Marja-Leena; Kielinen, Marko; Linna, Sirkka-Liisa; Jussila, Katja; Ebeling, Hanna; Bloigu, Risto; Joseph, Robert M; Moilanen, Irma

    2011-06-01

    The latest definitions of autism spectrum disorders (ASDs) were specified in DSM-IV-TR in 2000. DSM-5 criteria are planned for 2013. Here, we estimated the prevalence of ASDs and autism according to DSM-IV-TR, clarified confusion concerning diagnostic criteria, and evaluated DSM-5 draft criteria for ASD posted by the American Psychiatry Association (APA) in February 2010. This was an epidemiological study of 5,484 eight-year-old children in Finland, 4,422 (81%) of them rated via the Autism Spectrum Screening Questionnaire by parents and/or teachers, and 110 examined by using a structured interview, semi-structured observation, IQ measurement, school-day observation, and patient records. Diagnoses were assigned according to DSM-IV-TR criteria and DSM-5 draft criteria in children with a full-scale IQ (FSIQ) ≥50. Patient records were evaluated in children with an FSIQ autism 4.1 in 1,000 according to DSM-IV-TR. Of the subjects with ASDs and autism, 65% and 61% were high-functioning (FSIQ ≥70), respectively. The prevalence of pervasive developmental disorder not otherwise specified was not estimated because of inconsistency in DSM-IV-TR criteria. DSM-5 draft criteria were shown to be less sensitive in regard to identification of subjects with ASDs, particularly those with Asperger's syndrome and some high-functioning subjects with autism. DSM-IV-TR helps with the definition of ASDs only up to a point. We suggest modifications to five details of DSM-5 draft criteria posted by the APA in February 2010. Completing revision of DSM criteria for ASDs is a challenging task. Copyright © 2011 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.

  11. The Music and the Limits of the World. A Study on Eugenio Trías and Augustine of Hippo

    Directory of Open Access Journals (Sweden)

    Diego I. Rosales Meana

    2013-07-01

    Full Text Available This work focuses on the role that music has in the constitution of the World as a philosophical category. I explore the work of Eugenio Trías and Augustine of Hippo, and the way both philosophers have conceptualized music in relation to the constitution of the time of the World. For Trías music is not about the World but about its limits and, in that way, gives it a form. For Augustine music relates man to universe’s ordo, liberating him from mundane distentio animi and helping him to give sense to a World that gives itself as finite.

  12. Taxa de mortalidade por acidentes de trâsito e frota de veículos

    Directory of Open Access Journals (Sweden)

    Samuel Kilsztajn

    2001-06-01

    Full Text Available OBJETIVO: A taxa de mortalidade específica por acidentes de trânsito de veículos a motor é usualmente utilizada para efeito das políticas de saúde pública. Para mensurar o grau de violência no trânsito, foi realizado estudo com o objetivo de analisar o número de óbitos por acidentes de trânsito por veículo a motor. MÉTODOS: Com base nos dados sobre frota de veículos, população e óbitos por acidente de trânsito, publicados no Statiscal Yearbook (1999, Demografic Yearbook (1997, Denatran (1999, Ministério da Saúde (2000 e Fundação IBGE (2000, foram estudados 61 países e 51 localidades brasileiras.A taxa de mortalidade específica foi decomposta em número de veículos por habitante e número de óbitos por veículo. Numa primeira aproximação, cada uma das amostras (internacional e brasileira foi subdividida em três grupos, de acordo com o número de veículos por habitante, para estudo da relação entre os três índices. Para testar a significância dessa relação, foi estimada uma função de regressão log-linear. RESULTADOS: Os resultados para as estimativas internacionais, assim como as do Brasil, demonstraram que, quanto maior o número de veículos por habitante, menor o número de óbitos por acidentes de trânsito por veículo, tendo-se elasticidade da ordem de -1,067, para as estimativas internacionais, e de -0,515, para as do Brasil. CONCLUSÕES: Para uma política de prevenção dos acidentes de trânsito, os resultados encontrados indicam a necessidade de estudar os fatores que possam explicar o maior número de óbitos por veículo nas regiões com menor número de veículos por habitante.

  13. T-R Cycle Characterization and Imaging: Advanced Diagnostic Methodology for Petroleum Reservoir and Trap Detection and Delineation

    Energy Technology Data Exchange (ETDEWEB)

    Ernest A. Mancini

    2006-08-30

    Characterization of stratigraphic sequences (T-R cycles or sequences) included outcrop studies, well log analysis and seismic reflection interpretation. These studies were performed by researchers at the University of Alabama, Wichita State University and McGill University. The outcrop, well log and seismic characterization studies were used to develop a depositional sequence model, a T-R cycle (sequence) model, and a sequence stratigraphy predictive model. The sequence stratigraphy predictive model developed in this study is based primarily on the modified T-R cycle (sequence) model. The T-R cycle (sequence) model using transgressive and regressive systems tracts and aggrading, backstepping, and infilling intervals or sections was found to be the most appropriate sequence stratigraphy model for the strata in the onshore interior salt basins of the Gulf of Mexico to improve petroleum stratigraphic trap and specific reservoir facies imaging, detection and delineation. The known petroleum reservoirs of the Mississippi Interior and North Louisiana Salt Basins were classified using T-R cycle (sequence) terminology. The transgressive backstepping reservoirs have been the most productive of oil, and the transgressive backstepping and regressive infilling reservoirs have been the most productive of gas. Exploration strategies were formulated using the sequence stratigraphy predictive model and the classification of the known petroleum reservoirs utilizing T-R cycle (sequence) terminology. The well log signatures and seismic reflector patterns were determined to be distinctive for the aggrading, backstepping and infilling sections of the T-R cycle (sequence) and as such, well log and seismic data are useful for recognizing and defining potential reservoir facies. The use of the sequence stratigraphy predictive model, in combination with the knowledge of how the distinctive characteristics of the T-R system tracts and their subdivisions are expressed in well log patterns

  14. Sør-Trøndelag Aktivitets-Relaterte Tiltak (START – Samhandling for bedre helse

    Directory of Open Access Journals (Sweden)

    Tommy Aune Rehn

    2011-08-01

    Full Text Available Høy forekomst av kroniske sykdommer og stigende helseutgifter representerer i lys av den kommende eldrebølgenen stor samfunnsøkonomisk utfordring. Den negative helseutviklingen er i ferd med å bli et nasjonalt problem og må få konsekvenser for fremtidig norsk helsepolitikk. Fysisk inaktivitet er en livsstilsfaktor som er sterkt assosiert med lavt nivå av kondisjon, total dødelighet og død av hjerte- og karsykdom. Studier viser at selv en liten bedring i kondisjon forventes å gi betydelig økt forventet levealder og at individer som har et bra kondisjonsnivå har opptil 15 flere leveår med god helse hvor de er selvhjulpne. Økt fysisk aktivitet har en gunstig effekt på alle risikofaktorer for kronisk sykdom og tidlig død, og vi mener derfor at man bør legge til rette for å øke det generelle fysiske aktivitetsnivået i befolkningen og bedre kunnskapen om fysisk aktivitet. Økt fysisk aktivitet vil forventes å bedre folkehelsen ved å redusere sykdomsforekomst, medisinbruk og dødelighet samt øke arbeidsevnen i populasjonen, noe som igjen vil redusere de samfunnsøkonomiske utgiftene. For å lykkes med dette, har vi tatt initiativ til prosjektet ”Sør-Trøndelag Aktivitets-Relaterte Tiltak” (START, som er tenkt å være en koordinert populasjonsbasert samhandling for bedre helse gjennom økt fysisk aktivitet rettet mot alle lag i befolkningen, fra krybbe til grav. Målet er at START skal danne grunnlag for nasjonal implementering av tiltak slik at vi oppnår en helsepolitisk bærekraftig utvikling i årene som kommer. Denne artikkelenbeskriver START og bakgrunnen for prosjektet.Rehn TA, Rognmo Ø, Ingebrigtsen JE, Vik JT, Wisløff U. Sør-Trøndelag Activity-Related Trial (START –Cooperation for better health. Nor J Epidemiol 2011; 20 (2: 209-216.ENGLISH SUMMARYHigh incidence of chronic diseases and rising health expenditure represents in light of the increasing proportion of elderly in our society a development that cannot

  15. Distribuidor de tránsito «La Araña» (Venezuela

    Directory of Open Access Journals (Sweden)

    Editorial, Equipo

    1965-12-01

    Full Text Available The location of Caracas city, the road system that converges on it, and the rapid growth of the town in a particular direction due to the special topography of the neighborhood, have led to very considerable traffic difficulties. To guide this traffic correctly it has been necessary to build a traffic distributor; called «the spider», at which traffic crosses at four different levels. Obviously, serious technical problems have had to be faced to overcome the low strength of the soil, and its difficult contours. Owing to the large size and extension of the project, the precasting of many special units has been a most important factor. The girders and structural columns are of prestressed concrete, and the foundations, which rest on a variety of piles, are of reinforced concrete. The project has been financed by the Ministry of Public Works, and is now in an advanced state of completion, but the final stage is yet to be done. The total budget for this project is about 600 m. pesetas. The present article describes the total work and gives some brief details on the methods of calculation and execution that were adopted.La situación de Caracas y el sistema vial que concurre en su casco urbano, junto con la expansión de la ciudad en una dirección determinada, provocada por condiciones topográficas locales, han creado un problema de encauzamiento del tránsito que culmina en la necesidad de construir un distribuidor de tráfico, denominado «La Araña», en el que se cruzan las calzadas a cuatro niveles distintos. Como es lógico, se han tenido que afrontar serios problemas técnicos para vencer accidentes locales y terrenos de apoyo de pobre capacidad de sustentación. Dado el gran volumen, variedad y dispersión de obras, la prefabricación de elementos básicos ha sido imperiosa. Las vigas y entramados estructurales son de hormigón pretensado, y los cimientos, con bases apoyadas sobre pilotes de distintos tipos, de hormigón armado ordinario

  16. MPID-T2: a database for sequence-structure-function analyses of pMHC and TR/pMHC structures.

    Science.gov (United States)

    Khan, Javed Mohammed; Cheruku, Harish Reddy; Tong, Joo Chuan; Ranganathan, Shoba

    2011-04-15

    Sequence-structure-function information is critical in understanding the mechanism of pMHC and TR/pMHC binding and recognition. A database for sequence-structure-function information on pMHC and TR/pMHC interactions, MHC-Peptide Interaction Database-TR version 2 (MPID-T2), is now available augmented with the latest PDB and IMGT/3Dstructure-DB data, advanced features and new parameters for the analysis of pMHC and TR/pMHC structures. http://biolinfo.org/mpid-t2. shoba.ranganathan@mq.edu.au Supplementary data are available at Bioinformatics online.

  17. ATMOSPHERE AND SPECTRAL MODELS OF THE KEPLER-FIELD PLANETS HAT-P-7b AND TrES-2

    International Nuclear Information System (INIS)

    Spiegel, David S.; Burrows, Adam

    2010-01-01

    We develop atmosphere models of two of the three Kepler-field planets that were known prior to the start of the Kepler mission (HAT-P-7b and TrES-2). We find that published Kepler and Spitzer data for HAT-P-7b appear to require an extremely hot upper atmosphere on the dayside, with a strong thermal inversion and little day-night redistribution. The Spitzer data for TrES-2 suggest a mild thermal inversion with moderate day-night redistribution. We examine the effect of nonequilibrium chemistry on TrES-2 model atmospheres and find that methane levels must be adjusted by extreme amounts in order to cause even mild changes in atmospheric structure and emergent spectra. Our best-fit models to the Spitzer data for TrES-2 lead us to predict a low secondary eclipse planet-star flux ratio (∼ -5 ) in the Kepler bandpass, which is consistent with what very recent observations have found. Finally, we consider how the Kepler-band optical flux from a hot exoplanet depends on the strength of a possible extra optical absorber in the upper atmosphere. We find that the optical flux is not monotonic in optical opacity, and the non-monotonicity is greater for brighter, hotter stars.

  18. A atualidade dos acidentes de trânsito na era da velocidade: uma visão geral

    Directory of Open Access Journals (Sweden)

    Marín Letícia

    2000-01-01

    Full Text Available Este artigo focaliza, numa perspectiva interdisciplinar, os estudos sobre acidentes de trânsito em escala nacional e internacional. Ele começa analisando o aumento da produção e consumo de veículos motorizados em todo o mundo e as transformações sociais que esse fato acarretou. Atenção especial é dada à degradação do meio ambiente urbano e ao enorme custo social representado pelos acidentes de trânsito. Em seguida, é apresentado um panorama epidemiológico sobre as vítimas do trânsito. A relação entre personalidade e acidente de trânsito mereceu atenção especial, principalmente no que se refere ao comportamento infrator e ao consumo de bebidas alcoólicas e de outras drogas. O artigo conclui enfatizando a necessidade de o Estado implementar políticas públicas específicas consistentes, a fim de se poder controlar o problema.

  19. Variability among Research Diagnostic Interview Instruments in the Application of "DSM-IV-TR" Criteria for Pediatric Bipolar Disorder

    Science.gov (United States)

    Galanter, Cathryn A.; Hundt, Stephanie R.; Goyal, Parag; Le, Jenna; Fisher, Prudence W.

    2012-01-01

    Objective: The "DSM-IV-TR "criteria for a manic episode and bipolar disorder (BD) were developed for adults but are used for children. The manner in which clinicians and researchers interpret these criteria may have contributed to the increase in BD diagnoses given to youth. Research interviews are designed to improve diagnostic reliability and…

  20. Anette Poder: "Historiebevidsthed og kronologi. Om den røde tråd i historie", 2016

    DEFF Research Database (Denmark)

    Grevy, Carlo

    2017-01-01

    Folkeskolelærer Anette Poder fortæller i dette artikeluddrag om folkeskolens undervisning i historiekanonen (2006) på baggrund af sine observationer i folkeskoler i 2013. På de observerede skoler blev der undervist efter princippet den røde tråd, hvor forskellige historiekanonpunkter blev...

  1. Investigation of the ferroelectric switching behavior of P(VDF-TrFE)-PMMA blended films for synaptic device applications

    International Nuclear Information System (INIS)

    Kim, E J; Kim, K A; Yoon, S M

    2016-01-01

    Synaptic plasticity can be mimicked by electronic synaptic devices. By using ferroelectric thin films as gate insulator for thin-film transistors (TFT), channel conductance can be defined as the synaptic plasticity, and gradually modulated by the variations in amounts of aligned ferroelectric dipoles. Poly(vinylidene fluoride-trifluoroethylene) [P(VDF-TrFE)]-poly(methyl methacrylate) (PMMA) blended films are chosen and their switching kinetics are investigated by using the Kolmogorov-Avrami-Ishibashi model. The switching time for ferroelectric polarization is sensitively influenced by the amplitude of applied electric field and volumetric ratio of ferroelectric beta-phases in the P(VDF-TrFE)-PMMA films. The switching time of the P(VDF-TrFE) increases with decreasing the pulse amplitude and/or the ratio of ferroelectric beta-phases by incorporation of PMMA. The activation electric field is also found to increase as the increase in blended amount of PMMA. Synapse TFTs are fabricated using the P(VDF-TrFE)-PMMA as gate insulator and In-Ga-Zn-O active channels. The drain currents of the synapse TFTs gradually increased when the voltage pulse signals with given duration are repeatedly applied. This suggests that the synaptic weights can be modulated by the number of external pulse signals, and that the proposed synapse TFT can be applied for mimicking the operations of bio-synapses. (paper)

  2. Impaired renal secretion of substrates for the multidrug resistance protein 2 in mutant transport-deficient (TR-) rats.

    NARCIS (Netherlands)

    Masereeuw, R.; Notenboom, S.; Smeets, P.H.E.; Wouterse, A.C.; Russel, F.G.M.

    2003-01-01

    Previous studies with mutant transport-deficient rats (TR(-)), in which the multidrug resistance protein 2 (Mrp2) is lacking, have emphasized the importance of this transport protein in the biliary excretion of a wide variety of glutathione conjugates, glucuronides, and other organic anions. Mrp2 is

  3. TR{alpha}- and TSH-mRNA levels after temporal exposition with methimazole in zebrafish, Danio rerio

    Energy Technology Data Exchange (ETDEWEB)

    Schulz, A.E.I.; Stocker, A.; Hollosi, L.; Schramm, K.W. [Inst. of Ecological Chemistry, GSF - National Research Center for Environment and Health (Germany)

    2004-09-15

    The group of dioxin and dioxin-like substances are highly persistent in the environment. There are evidences from present investigations that a variety of substances are capable of disrupting the endocrine system in the aquatic environment. These substances are called endocrine disruptors. Dioxin and related compounds can act as endocrine disruptors. Aquatic animals like amphibian and fish are especially affected of the impact of these compounds. Investigations concerned so far in particular the domain of reproduction biology and the thyroid axis especially. Recent investigations showed that the TR{alpha}-mRNA level change after a short temporal expression with T3, methimazole and amiodarone. The objective of the project is to identify effects of thyroid endocrine disruptors on the regulation of gene expression of the thyroid receptors TR{alpha}a, TR{beta} and thyroid stimulating hormone TSH and associated effects on other system. In preliminary studies the effects of the drug methimazole as model substance on gene expression of TR{alpha} and TSH were investigated. Methimazole is an inhibitor of the thyroid peroxidase so that the formation of thyroid hormones is disrupted.

  4. Investigation of aeroacoustics and flow dynamics of a NACA 0015 airfoil with a Gurney flap using TR-PIV

    NARCIS (Netherlands)

    Shah, J.; Sciacchitano, A.; Pröbsting, S.

    The present study employs simultaneous planar TR-PIV and microphone measurements to obtain the flow dynamics and aeroacoustic causality correlation associated with a Gurney flap of various sizes in case of low Mach and high Reynolds number flows. The objectives are to investigate the secondary

  5. La tríada oscura de la personalidad: maquiavelismo, narcisismo y psicopatía. Una mirada evolutiva

    Directory of Open Access Journals (Sweden)

    Fernando Renee González Moraga

    2015-08-01

    Full Text Available Se aborda la denominada Tríada Oscura de la Personalidad -Tríada- (maquiavelismo, narcisismo subclínico y psicopatía subclínica desde una mirada evolutiva. El objetivo de esta investigación es revisar la evidencia que han presentado los teóricos evolucionistas sobre la Tríada, desde un acercamiento a la mirada evolutiva. Para esto, se indaga en las principales características de cada uno de estos rasgos, los instrumentos que se han utilizado para evaluarlos y las principales áreas en donde se han estudiado. La mirada evolutiva plantea que los rasgos de la Tríada son dimensionales y varían de acuerdo con las diversas estrategias que utilizan los sujetos para adaptarse a las características socioambientales en las que se desarrollan. Estos rasgos se caracterizan por presentar violencia psicológica, inhibición moral, manipulación, baja amabilidad, insensibilidad, egoísmo y dificultad para mentalizar en contextos de interacción interpersonal y social.

  6. Management of Fusarium oxysporum f.sp cubense (Foc-TR4) from banana by anaerobic soil disinfestation (ASD)

    NARCIS (Netherlands)

    Runia, W.T.

    2014-01-01

    Applied Plant Research in Lelystad has, commissioned by Gert Kema, Plant Research International (PRI) and leader of the Panama Project, performed a trial to measure the efficacy of anaerobic soil disinfestation (ASD) with a ‘Herbie” product against Fusarium oxysporum f.sp. cubense (Foc; TR 4),

  7. As de basura. El tráfico ilegal de residuos

    Directory of Open Access Journals (Sweden)

    Ulderico Pesce

    2016-01-01

    Full Text Available Ulderico Pesce (Rivello, 1963, uno de los más significativos autores-narradores del teatro de narración de marcado contenido civil, vuelve a tratar en Asso di Monnezza el inmenso problema del lucrativo reciclaje de deshechos, sobre todo industriales, en la Italia actual. No es esta la primera vez que trata el tema, aunque en esta ocasión, partiendo de la visión directa del joven Nicola, se centra en la sangrante connivencia entre mafia, entidades públicas y los bajos fondos metropolitanos. En esta línea de denuncia social se mueven, de hecho, todos sus espectáculos de narración  en la línea del llamado teatro civile, como Storie di scorie. Il pericolo nucleare in Italia, sobre el peligro nuclear en tierras italianas; FIATo sul collo, sobre los 21 días de lucha de los trabajadores de la Fiat en Melfi; L'innaffiatore del cervello di Passannante: L'anarchico che cercò di uccidere Umberto I di Savoia, sobre la trágica figura histórica de Passannante, quien intentó asesinar al rey Umberto I en 1878; o Il Triangolo degli schiavi: I lavoratori clandestini in Italia, un áspero montaje sobre las pésimas condiciones laborales de algunos inmigrantes en tierras italianas, como muy bien indica el título.

  8. Dor-desprazer-trabalho docente: como desfazer essa tríade

    Directory of Open Access Journals (Sweden)

    Maria Elizabeth Barros de Barros

    2007-12-01

    Full Text Available O artigo apresenta a experiência do Programa de Formação e Investigação Sobre a Saúde e o Trabalho (PFST de docentes de escolas públicas, desenvolvido na Universidade Federal do Espírito Santo. Trata da problemática da saúde do conjunto de docentes que trabalham nas escolas públicas do município da Serra/ES, visando a desfazer a tríade dor-desprazer-trabalho docente, vivida de forma naturalizada pelo coletivo de docentes. Pretende avançar na compreensão das relações saúde-trabalho nas escolas e investigar as estratégias utilizadas por esses professores para resistirem às tentativas de desqualificação do trabalho docente. Afirma a possibilidade de se abrirem espaços de discussão no cotidiano dos docentes para que a luta pela saúde se constitua em redes de cooperação entre sujeitos e escolas, inaugurando-se outras formas de atuação desses estabelecimentos. Com esse objetivo, propõe uma metodologia de trabalho que tem se pautado na abordagem ergológica, construída na Universidade de Provença, em AIX/ França.

  9. Reducing the sound emission of TR 07 and effects on the German regulation ``Schall-Transrapid``

    Energy Technology Data Exchange (ETDEWEB)

    Schmitz, K P [Industrieanlagen-Betriebsgesellschaft mbH, Magnetbahn-Versuchsanlage, Lathen/Ems (Germany); Wolters, C [Industrieanlagen-Betriebsgesellschaft mbH, Magnetbahn-Versuchsanlage, Lathen/Ems (Germany)

    1996-12-31

    To introduce a new maglev train systems in modern Germany it is important to know its sound emission. Conventional sound measurements were done on the maglev train TRANSRAPID 07 (TR07) to get all the values that are important for planning a new line. Furthermore a microphone array equipment was used to detect the dominant sound sources and their positions on the surface of the train. In a second step the shape was optimazed based on the acoustical investigations. The changes were made especially in the lower part of the bow. This configuration was measured again; the reduction of the noise emission was 3 dB(A) for the changed vehicle. As an example for the low sound emissions the planned schedule for the in service trains of the link between Hamburg and Berlin is reflected on the german regulations for the sound immissions. The result is that there is nearly no need of sound barriers. To use a speed of 200 km/h within the cities a distance of 16 m from the centreline to an immission point is needed. Outside the cities speeds of 400 km/h are possible for a distance of more than 53 m during the nighttime and of more than 23 m during the daytime. (orig.)

  10. Del tráfico entre antropología y arte contemporáneo

    Directory of Open Access Journals (Sweden)

    Xavier Andrade

    2007-06-01

    Full Text Available Tomando los estudios sobre la economía de las drogas ilícitas como referente metodológico, el artículo discute preliminarmente la noción de “tráfico” en relación a cuatro aspectos del cruce de fronteras entre la antropología y el arte contemporáneo. 1. Transportar o movilizar bienes –en este caso, simbólicos, esto es básicamente ideas, categorías y conceptos pero también estrategias de apropiación y recontextualización pertinentes tanto a la etnografía como al arte contemporáneo. 2. Describir el carácter “contaminante” que tales bienes eventualmente adquieren cuando circulan en diferentes contextos (académico, gestión cultural, artes visuales, provocando por ello estrategias defensivas entre unos y otros. 3. Dar cuenta del carácter conflictivo de las micro-prácticas que se ponen a prueba durante el diálogo entre distintos saberes sancionados académicamente como campos o disciplinas. 4. Discutir los códigos de la ilegalidad que acompañan a la calidad de “traficante” y el capital simbólico que se deriva de ello.

  11. Spontaneous quaternary and tertiary T-R transitions of human hemoglobin in molecular dynamics simulation.

    Directory of Open Access Journals (Sweden)

    Jochen S Hub

    2010-05-01

    Full Text Available We present molecular dynamics simulations of unliganded human hemoglobin (Hb A under physiological conditions, starting from the R, R2, and T state. The simulations were carried out with protonated and deprotonated HC3 histidines His(beta146, and they sum up to a total length of 5.6 micros. We observe spontaneous and reproducible T-->R quaternary transitions of the Hb tetramer and tertiary transitions of the alpha and beta subunits, as detected from principal component projections, from an RMSD measure, and from rigid body rotation analysis. The simulations reveal a marked asymmetry between the alpha and beta subunits. Using the mutual information as correlation measure, we find that the beta subunits are substantially more strongly linked to the quaternary transition than the alpha subunits. In addition, the tertiary populations of the alpha and beta subunits differ substantially, with the beta subunits showing a tendency towards R, and the alpha subunits showing a tendency towards T. Based on the simulation results, we present a transition pathway for coupled quaternary and tertiary transitions between the R and T conformations of Hb.

  12. Medeia na Argonáutica: um plano trágico de Argo

    Directory of Open Access Journals (Sweden)

    Fábio Gerônimo Mota Diniz

    2011-06-01

    Full Text Available O propósito desse trabalho é analisar como a relação entre os personagens Medeia e Jasão na Argonáutica de Apolônio de Rodes se estabelece a partir de seu encontro no canto III da obra, por intermédio da discussão acerca do poder de sedução do discurso de Jasão. Exemplos do canto III da obra permitirão compreender como Argo, sobrinho de Medeia, utiliza as habilidades retóricas de Jasão para conquistar o auxílio de Medeia no cumprimento das provas que levarão à conquista do velo de ouro. Além disso, uma análise mais atenta permitirá entender como Apolônio insere nesse discurso elementos ligados a Medeia de Eurípides, fazendo com que a Argonáutica sirva como uma antecipação das situações da peça trágica. 

  13. Envolvimento paterno aos três meses de vida do bebê

    Directory of Open Access Journals (Sweden)

    Cesar Augusto Piccinini

    Full Text Available O presente estudo investigou o envolvimento paterno aos três meses de vida do bebê. Foram entrevistados 38 pais primíparos, com idades entre 20 e 40 anos. Realizou-se uma análise de conteúdo baseada nas dimensões do conceito de envolvimento paterno: interação, acessibilidade e responsabilidade. Os pais revelaram envolverem-se nas atividades de cuidado, embora nem sempre de maneira rotineira. Também relataram preocupações e envolvimento nas decisões relativas aos cuidados, educação e saúde do bebê. Contudo, consideravam que sua participação estava aquém da ideal em função das restrições impostas pelo trabalho. Os resultados apontam para um aumento no envolvimento paterno nos primeiros meses do bebê e para a necessidade de apoio aos pais neste momento de transição familiar.

  14. Focusing and bunching of ion beam in axial injection channel of IPHC cyclotron TR24

    Science.gov (United States)

    Adam, T.; Ivanenko, I.; Kazarinov, N.; Osswald, F.; Traykov, E.

    2017-07-01

    The CYRCe cyclotron (CYclotron pour la ReCherche et l’Enseignement) is used at IPHC (Institut Pluridisciplinaire Hubert Curien) for the production of radio-isotopes for diagnostics, medical treatments and fundamental research in radiobiology. The TR24 cyclotron produced and commercialized by ACSI (Canada) delivers a 16-25 MeV proton beam with intensity from few nA up to 500 μA. The solenoidal focusing instead of existing quadrupole one is proposed in this report. The changing of the focusing elements will give the better beam matching with the acceptance of the spiral inflector of the cyclotron. The parameters of the focusing solenoid are found. Additionally, the main parameters of the bunching system are evaluated in the presence of the beam space charge. This system consists of the buncher installed in the axial injection beam line of the cyclotron. The using of the grid-less multi harmonic buncher may increase the accelerated beam current and will give the opportunity to new proton beam applications.

  15. CaCO3-N İlişkieri 3.Nötr Toprakta

    OpenAIRE

    Aydeniz, A.; BROHİ, A.R.

    1990-01-01

    Nötral toprakta azot-kireç ilişkilerini açıklayabilmek için kireç içermeyen, nötr hafif alkali,bazaltlık kökenli Siverek toprağı alınarak bu¬na 9 düzeyde (% 0-0.5-1-1.5-2-3-4-5-10) kireç ve8 düzeyde (0-1-5-20-50 100-200-50 ppm) azot katmak suretiyle hazırlanan topraklarda; büyütme odasında, mini - biyolojik yöntemle domates yetiştirmek ve 65 gün son¬ra- hasat etmek suretiyle yapman araştırma sonuçları şu şekilde özetle¬nebilir 1. Asit toprakta, kireç katılmayan (CaC03 0> örneklerden orta...

  16. A Turkish version of myocardial infarction dimensional assessment scale (TR-MIDAS): reliability-validity assesment.

    Science.gov (United States)

    Uysal, Hilal; Ozcan, Şeyda

    2011-06-01

    Many new measuring devices have been developed so that broader psychometric measurements in the coronary artery disease, disease-specific health status measurements, and identification of the broader quality of life can be performed in the recent years. The study was intended to determine whether, and to what extent, MIDAS is a valid and reliable measurement to the patients suffering from myocardial infarction for the first time in Turkey. The research was conducted with the patients hospitalized and treated with myocardial infarction in the cardiology departments of 2 hospitals in Istanbul, Turkey, between 2007 and 2008. Psychometric evaluations of TR-MIDAS were used for validity studies; language validity, content validity, construct validity were examined. For reliability studies; the tool's internal consistency reliability, Cronbach's alpha reliability coefficient, and test-retest reliability were completed. The instrument's content validity index was determined to be "0.95". Principal component analysis revealed six factors with an eigenvalue >1.5. Cronbach's alpha was found to be 0.89 for total scale which was an acceptable value. The total's test-retest reliability was 0.51 (p<0.01). Data obtained at the end of the study supports that Turkish Myocardial Infarction Dimensional Assessment Scale is a valid and reliable instrument as a disease-specific scale to assess the patients' quality of life suffering from myocardial infarction in Turkey. Copyright © 2010 European Society of Cardiology. Published by Elsevier B.V. All rights reserved.

  17. La experiencia del embarazo en el tránsito de la adolescencia

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    Alicia Genolet

    2004-01-01

    Full Text Available El presente artículo expone el comportamiento estadístico de las madres adolescentes atendidas en su parto en el Servicio de Maternidad del Hospital «San Roque» (Paraná, Entre Ríos durante 1997, 1998 y 1999, y las vivencias y representaciones que portan un grupo de adolescentes (madres y no madres con relación a la maternidad y la anticoconcepción. El estudio estadístico se basó en una muestra de 890 fichas de parto, que fueron procesadas con el software SPSS. Por otra parte, la interpretación de los datos cualitativos permite construir las siguientes conceptualizaciones: Las adolescentes estudiadas sufren condiciones que hablan de una triple vulnerabilidad: por ser mujeres, por ser pobres y por ser adolescentes. La adolescencia constituye un momento de vulnerabilidad de los sujetos en su tránsito a la adultez, que cobra una significación especial cuando tiene lugar en situaciones de riesgo, fragilidad y precariedad en los vínculos relacionales, familiares y sociales. Las condiciones de vulnerabilidad y pobreza refuerzan la condición subordinada del género femenino: ejercicio de roles tradicionales (crianza de los hijos, trabajo doméstico, exclusión de instancias de participación social y educativas.

  18. FIVE NEW TRANSIT EPOCHS OF THE EXOPLANET OGLE-TR-111b

    International Nuclear Information System (INIS)

    Hoyer, S.; Rojo, P.; Lopez-Morales, M.; DIaz, R. F.; Chambers, J.; Minniti, D.

    2011-01-01

    We report five new transit epochs of the extrasolar planet OGLE-TR-111b, observed in the v-HIGH and Bessell I bands with the FORS1 and FORS2 at the ESO Very Large Telescope between 2008 April and May. The new transits have been combined with all previously published transit data for this planet to provide a new transit timing variations (TTVs) analysis of its orbit. We find no TTVs with amplitudes larger than 1.5 minutes over a four-year observation time baseline, in agreement with the recent result by Adams et al. Dynamical simulations fully exclude the presence of additional planets in the system with masses greater than 1.3, 0.4, and 0.5 M + at the 3:2, 1:2, and 2:1 resonances, respectively. We also place an upper limit of about 30 M + on the mass of potential second planets in the region between the 3:2 and 1:2 mean-motion resonances.

  19. Mise-en-film da fotografia em três documentários brasileiros

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    Glaura Cardoso Vale

    2016-08-01

    Full Text Available Este artigo busca analisar, em três filmes da cinematografia brasileira recente, os modos como a fotografia, entendida como dispositivo de rememoração, é colocada em cena, compreendendo-a como rastro da presença de algo que já se tornou ausente. Pretende-se discutir como, ao solicitar imagens retiradas dos "álbuns de família", corrobora-se a construção de narrativas que dão a ver a biografia de homens e mulheres comuns, reais ou imaginados pelo documentário. Verificar, em metodologias distintas, o exercício político e estético do fazer cinematográfico que expõe as fragilidades e possíveis frustrações na reconstrução de algo longínquo (do ponto de vista do personagem e desconhecido (do ponto de vista dos autores, por mais presente materialmente que esteja a imagem no ato da rememoração.

  20. Três mulheres no nazismo: Reflexões sobre as fontes do comportamento moral

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    Maria Claudia Coelho

    2009-07-01

    Full Text Available Este trabalho discute as fontes do comportamento moral. Seu ponto de partida é a crítica feita à sociologia da moral durkheimiana por Zygmunt Bauman, que problematiza os pressupostos da origem social da moral e sua natureza coercitiva. Bauman contrapropõe, com base nas obras de Hannah Arendt e Emmanuel Lévinas, uma concepção de moralidade cujo núcleo é a responsabilidade para com o outro. A discussão é empreendida com base em três filmes que retratam cada qual a trajetória de uma mulher durante o nazismo: Traudl Junge, Sophie Scholl e Leni Riefenstahl. O eixo da análise é o modo como responsabilidade, culpa e consciência se entrelaçam em suas trajetórias. This article discusses the sources of moral behaviour. Its point of departure is Zygmunt Bauman’s criticism of the Durkheimian sociology of morality, challenging the assumptions of the social origin of morality and its coercive nature. Drawing on Hannah Arendt’s and Emmanuel Levinas’ works, Bauman counter-proposes a concept of morality based on responsibility toward each other. The discussion is then developed in relation to three fi lms that portray, each in their own way, the experience of a woman during the Nazi regime: Traudl Junge, Sophie Scholl and Leni Riefenstahl. The analysis is centred on how responsibility, guilt and conscience intertwine in the course of those lives.

  1. A cobertura de ciência em três jornais paraenses: um estudo longitudinal

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    Vanessa Brasil de Carvalho

    Full Text Available Resumo Neste artigo, apresentamos uma proposta metodológica visando realizar um estudo longitudinal que fornecesse um panorama da cobertura de ciência em 130 anos, por três jornais importantes do Estado do Pará: A Província do Pará (1876-2002, Folha do Norte (1896-1974 e O Liberal (1946-atual. Analisamos um período de dois meses a cada dez anos, de 1876 a 2006, em cada jornal selecionado, de maneira que obtivemos um olhar em longo prazo que perpassou pela história dos periódicos e, portanto, por grande parte da história da imprensa no Pará e na Amazônia. Utilizamos análise de conteúdo e análise de frames da Mídia. Nossos dados mostram que houve ênfase na pesquisa em saúde, destaque para a ciência nacional e preocupação em contextualizar os fatos científicos. Controvérsias e incertezas científicas ganharam pouco espaço nos jornais analisados.

  2. Um mundo metafísico nos trópicos

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    Else Ribeiro Pires Vieira

    2008-04-01

    Full Text Available A fonte torna-se a estrela inatingível e pura que, sem se deixar contaminar, contamina, brilha para os artistas dos países da América Latina... ilumina os movimentos das mãos, mas ao mesmo tempo torna os artistas súditos do seu magnetismo superior.. Silviano Santiago, Uma literatura nos trópicos Afastando-me do discurso crítico em torno das influências e do caráter tributário a ele inerente, sobre o qual nos adverte Santiago já em ensaio de 1971,1 afastando-me, igualmente, de Polarizações hierarquizadas como fonte/alvo, situando-me na fronteira fluida do transformar de escritas/reescritas e nela privilegiando áreas de permeabilidade entre os discursos e o seu jogo relacional, ofereço, neste texto, reflexões em torno da poesia metafísica inglesa traduzida entre 1978 e 1991 na sua interseção com outras produções textuais brasileiras no período de início da abertura política, gestação e nascimento da Nova República2 . Traduzir a Inglaterra, ler o Brasil. O que se traduz? Quem se traduz? Por que se traduz? Como se traduz?

  3. Os três maiores “equívocos” na Teoria da Relatividade de Einstein

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    Roberto A. Monti

    1999-05-01

    Full Text Available É chegado o momento de esclarecer os três maiores “equívocos” comumente ensinados nas escolas e universidades em todo o mundo: 1. Os experimentos de Michelson-Morley-Miller nunca deram um “resultado nulo”, contrariamente ao que é estabelecido na maioria dos livros-textos de física. 2. Os resultados experimentais do eclipse solar de 1919 nunca “provaram” a teoria da Relatividade (Geral de Einstein. A “diferença” entre a deflexão Newtoniana e a Einsteiniana de um feixe de luz nunca foram “confirmadas” após 1919. Pelo contrário, em 1960, resultados experimentais obtidos por Pound e Rebka mostraram que a energia (ou massa da luz está sujeita à gravitação Newtoniana da mesma forma que a matéria comum. 3. O “Big Bang” nunca ocorreu. Evidências experimentais mostram que Hubble e Nernst provaram claramente que o Universo não está se expandindo. Este resultado tem sido sempre confirmado por dados astrofísicos e pela física elementar.

  4. O TRABALHO EM ANDRÉ GORZ: três reflexões, uma problemática

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    Henrique Amorim

    Full Text Available Há aproximadamente dez anos André Gorz morreu, deixando ideias estimulantes sobre os limites e a necessidade de superação ou desconstrução da sociedade capitalista. Sempre atento às transformações sociais, Gorz chegou, em certos momentos, a sintetizar tudo que havia de mais profundo e crítico na teoria social. Entretanto, é possível observar, em sua obra, uma oscilação em relação ao lugar social que o trabalho ocupa. O lugar do trabalho parece mudar em função do desenvolvimento das forças produtivas. Assim, a análise do movimento social do trabalho na sociedade capitalista, realizada por Gorz, permanece prisioneira de uma determinação tecnológica e de um conceito de trabalho limitado ao universo produtivo das qualificações profissionais. Neste artigo, tenho como objetivo problematizar a concepção de trabalho exposta por Gorz em três de suas principais obras: Estratégia Operária e Neocapitalismo (1964, Adeus ao Proletariado (1980 e O Imaterial (2003, demonstrando como a teoria social e as alternativas políticas desenvolvidas por Gorz mudam vis-à-vis o lugar social ocupado pelo trabalho nessas obras.

  5. Field and city: Grande Sertão and Tristes Trópicos

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    Abel da Silveira Viana

    2008-07-01

    Full Text Available Until what point the intellectual improvement made possible the improvement in the social relations between field and city in Brazil of 20th century middle? The articulated and displayed images by important intellectuals were many times entailed to a supposed necessity of governmental public politics directed to the field inhabitant. The constatation takes us to at least two questions: the disguise of a superficial human being construction, which is, the idea of democratic State, based in a false politics unit, social and cultural, when not racial; and, as a consequence, the subjugation of social groups kept out of society, which the field inhabitant is one example. For the evaluation of this problem, we have two basic texts, for joining a important dimension to think about the problem of the representation and state homogenization: for being central in the debate on the relation field-city, and to establish dialogue with the academic thought of its time. These workmanships, which the article talks about, are Tristes trópicos, by Claude Lévi-Strauss, and Grande sertão: veredas by João Guimarães Rosa.

  6. Conceito de parceria: três projectos locais de promoção do emprego

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    Tiago Carrilho

    2008-01-01

    Full Text Available Neste estudo analisam-se as práticas de parceria em três projectos de promoção do emprego. Define-se parceria como o processo através do qual dois ou mais actores se relacionam na base de pressupostos-chave que têm tradução na dinâmica subjacente a determinado projecto. Nos projectos analisados, À Medida, Formart e Le Cheile, o trabalho em parceria traduz-se no envolvimento dos agentes institucionais na disponibilização de recursos, na articulação das tarefas e nas mudanças organizacionais. Esta base permite a promoção local do emprego numa perspectiva de maior integração social.This study analyzes partnership practices in three job promotion projects. Partnership is defined as a process in which two or more actors are associated on the basis of key assumptions which are reflected in the underlying dynamics of a given project. For the three projects analyzed, À Medida, Formart and Le Cheile, partnership work emerges in institutional actors' involvement in making resources available, in task co-ordination and in organizational change. This foundation makes it possible to promote employment within a wider scheme aimed at achieving social inclusion.

  7. The School Anxiety Scale-Teacher Report (SAS-TR): translation and psychometric properties of the Iranian version.

    Science.gov (United States)

    Hajiamini, Zahra; Mohamadi, Ashraf; Ebadi, Abbas; Fathi- Ashtiani, Ali; Tavousi, Mahmoud; Montazeri, Ali

    2012-07-18

    The School Anxiety Scale-Teacher Report (SAS-TR) was designed to assess anxiety in children at school. The SAS-TR is a proxy rated measure and could assess social anxiety, generalized anxiety and also gives a total anxiety score. This study aimed to translate and validate the SAS-TR in Iran. The translation and cultural adaptation of the original questionnaire were carried out in accordance with the published guidelines. A sample of students participated in the study. Reliability was estimated using internal consistency and test-retest analysis. Validity was assessed using content validity. The factor structure of the questionnaire was extracted by performing both exploratory and confirmatory factor analyses. In all 200 elementary students aged 6 to 10 years were studied. Considering the recommended cut-off values, overall the prevalence of high anxiety condition in elementary students was found to be 21 %. Cronbach's alpha coefficient for the Iranian SAS-TR was 0.92 and intraclass correlation coefficient (ICC) was found to be 0.81. The principal component analysis indicated a two-factor structure for the questionnaire (generalized and social anxiety) that jointly accounted for 55.3 % of variances observed. The confirmatory factory analysis also indicated a good fit to the data for the two-latent structure of the questionnaire. In general the findings suggest that the Iranian version of SAS-TR has satisfactory reliability, and validity for measuring anxiety in 6 to 10 years old children in Iran. It is simple and easy to use and now can be applied in future studies.

  8. The School Anxiety Scale-Teacher Report (SAS-TR: translation and psychometric properties of the Iranian version

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    Hajiamini Zahra

    2012-07-01

    Full Text Available Abstract Background The School Anxiety Scale-Teacher Report (SAS-TR was designed to assess anxiety in children at school. The SAS-TR is a proxy rated measure and could assess social anxiety, generalized anxiety and also gives a total anxiety score. This study aimed to translate and validate the SAS-TR in Iran. Methods The translation and cultural adaptation of the original questionnaire were carried out in accordance with the published guidelines. A sample of students participated in the study. Reliability was estimated using internal consistency and test-retest analysis. Validity was assessed using content validity. The factor structure of the questionnaire was extracted by performing both exploratory and confirmatory factor analyses. Results In all 200 elementary students aged 6 to 10 years were studied. Considering the recommended cut-off values, overall the prevalence of high anxiety condition in elementary students was found to be 21 %. Cronbach's alpha coefficient for the Iranian SAS-TR was 0.92 and intraclass correlation coefficient (ICC was found to be 0.81. The principal component analysis indicated a two-factor structure for the questionnaire (generalized and social anxiety that jointly accounted for 55.3 % of variances observed. The confirmatory factory analysis also indicated a good fit to the data for the two-latent structure of the questionnaire. Conclusion In general the findings suggest that the Iranian version of SAS-TR has satisfactory reliability, and validity for measuring anxiety in 6 to 10 years old children in Iran. It is simple and easy to use and now can be applied in future studies.

  9. Análise dos acidentes de trânsito ocorridos em uma Capital do Nordeste Brasileiro, em 2006.

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    Francisco José de Paula Júnior

    2013-06-01

    Full Text Available Este trabalho teve como objetivo descrever os acidentes de trânsito ocorridos na cidade de Fortaleza, capital do Ceará, no ano de 2006. Foi realizado um estudo descritivo, transversal, a partir de dados do Sistema de Informação de Acidentes de Trânsito de Fortaleza, que agrega todas as informações pertinentes aos acidentes de trânsito ocorridos na capital cearense, além de informações do Sistema de Informações Hospitalares. Esses dados foram analisados utilizando o software EPI INFO®. Em 2006, foram registrados 23.443 acidentes de trânsito. Desses, houve uma proporção de 2:1, entre homens e mulheres e os óbitos ocorreram principalmente na faixa etária de 30 a 59 anos, liderados por pedestres 141 (41,34% e motociclistas com 76 (22,28%. Entre os tipos de acidentes 14.267 (60,85% registraram-se colisões, tendo o mês de dezembro e o intervalo de 18 às 20 horas apresentado o maior número de registros. Em relação aos ferimentos, os motociclistas foram os mais lesionados, atingindo 5.634 (40,57% pessoas. Parte significativa dos acidentes e óbitos envolveu adolescentes e adultos jovens, resultando em 341 (0,71% vitimas que evoluíram para óbito. É fundamental estimular políticas públicas para melhoria nas condições de trânsito e um maior investimento para os sistemas que coletam informações sobre os acidentes.

  10. Method For Processing Spent (Trn,Zr)N Fuel

    Science.gov (United States)

    Miller, William E.; Richmann, Michael K.

    2004-07-27

    A new process for recycling spent nuclear fuels, in particular, mixed nitrides of transuranic elements and zirconium. The process consists of two electrorefiner cells in series configuration. A transuranic element such as plutonium is reduced at the cathode in the first cell, zirconium at the cathode in the second cell, and nitrogen-15 is released and captured for reuse to make transuranic and zirconium nitrides.

  11. Valor del atracurium en la intubación de la tráquea

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    Lincoln de la Parte Pérez

    2003-06-01

    Full Text Available La técnica de la intubación en el niño requiere de una relajación muscular profunda en un breve período, con un mínimo de repercusión hemodinámica. Aunque la intubación puede lograrse en poco tiempo después de la administración de succinilcolina, su uso se asocia con varios efectos secundarios, inaceptables en el niño programado para operación electiva. Los agentes relajantes musculares no despolarizantes disponibles anteriormente en nuestro medio, demoran mucho y no se emplean para la intubación de la tráquea en la mayoría de los hospitales. La introducción de un nuevo relajante no despolarizante con un inicio de acción breve y efectos hemodinámicos mínimos, soluciona muchas de nuestras dificultades anteriores. El atracurium posee múltiples ventajas para la intubación rápida de los pacientes de alto riesgo, en los cuales se necesite estabilidad hemodinámica y puede convertirse en el sustituto de la succinilcolina para la relajación muscular en las operaciones electivas. Se realizó un estudio de las condiciones obtenidas para la intubación de la tráquea, en un grupo de niños cardiópatas después de la administración de atracurium, en dosis promedio de 0,6 mg por kg de peso corporal. El tiempo promedio necesario para obtener una adecuada relajación muscular osciló entre los 90 y 120 s y se necesitaron dosis de mantenimiento a los 30 min como promedio. No se observaron efectos hemodinámicos ni complicaciones atribuibles al uso del relajante muscular.The intubation technique for the child requires a deep muscle relaxation in a short period of time, with a minimal hemodynamic repercussion. Although intubation may be accomplished shortly after the administration of succinylcholine, its use is associated with a number of side effects that are unacceptable in the child scheduled for elective surgery. The non-depolarizing muscle relaxants formerly available in our country delay too much and are not used for tracheal

  12. Resultados del tratamiento a pacientes con tríada terrible del codo

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    Héctor Gabriel Díaz Carrillo

    2015-04-01

    Full Text Available La luxación del codo, asociada a la fractura del proceso coronoideo y a la fractura de la cabeza radial, es denominada “tríada terrible del codo”, debido a la complejidad al abordar el tratamiento correcto y lo desalentador de los resultados que se obtienen con el mismo. Se realizó un estudio prospectivo, donde se recogen los resultados postoperatorios, obtenidos en cuatro pacientes con inestabilidad traumática aguda del codo, tratados entre enero de 2012 y mayo de 2013, que acudieron inicialmente al cuerpo de guardia del Hospital General Docente “Dr. Ernesto Guevara de La Serna” y tuvieron un seguimiento medio de ocho meses. El proceder consistió en reparación de la coronoides, del ligamento lateral externo, reparación de la cúpula radial, cupulectomía y colocación de pin endomedular; la técnica operatoria a emplear se definió por los estudios radiográficos realizados y los hallazgos en el transcurso del proceder. Los pacientes, tres hombres y una mujer, tuvieron cinco codos lesionados y un promedio de edad de 34 años. Como resultado del tratamiento la flexión fue normal entre 130-135° en 4 codos y limitada en uno a 110°, la extensión se encontró limitada de 8 a 21° en todos los pacientes, la pronosupinación se mantuvo limitada en todos los casos entre 5 y 22°. La intervención quirúrgica mediante fijación y reparación de los estabilizadores del codo proporcionó a corto plazo una funcionabilidad del codo cercana a la normalidad, los pacientes evolucionaron positivamente. Las complicaciones fueron: reluxación, infección local y aflojamiento de la osteosíntesis

  13. Concordance of DSM-5 and DSM-IV-TR classifications for autism spectrum disorder.

    Science.gov (United States)

    Ohashi, Kei; Mizuno, Yoshifumi; Miyachi, Taishi; Asai, Tomoko; Imaeda, Masayuki; Saitoh, Shinji

    2015-12-01

    The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) was published in May 2013. Autism spectrum disorder (ASD) has been structured for the three subtypes of pervasive developmental disorder (PDD), but the number of impairment in social and communication dimension is not stated. The subjects were 68 children who visited the Department of Psychology and Development at Nagoya City University Hospital for the first time between the ages of 6 and 15 years old. We retrospectively re-examined the subjects using DSM-IV-TR criteria and DSM-5 criteria with two rules (two of three and one of three on the social and communication dimension) and examined the concordance rate. Forty subjects were diagnosed with PDD, and 28 were not. The mean PDD subject age was 9.4 years, and mean IQ was 84.0 on the Wechsler Intelligence Scale for Children III or 62.7 on the Tanaka-Binet test. Twenty-seven (68%) of the PDD subjects were classified with ASD using DSM-5 criteria when the two of three rule was applied, while 32 (80%) were classified with ASD when the one of three rule was applied. All subjects without PDD were not diagnosed with ASD on DSM-5 criteria. DSM-5 criteria may exclude high functioning and older subjects from ASD because they tend to be atypical. The diagnostic procedure for DSM-5 criteria is ambiguous, especially in high functioning subjects and those diagnosed at an older age. © 2015 Japan Pediatric Society.

  14. DSM-IV-TR "pain disorder associated with psychological factors" as a nonhysterical form of somatization.

    Science.gov (United States)

    Aragona, Massimiliano; Tarsitani, Lorenzo; De Nitto, Serena; Inghilleri, Maurizio

    2008-01-01

    Elevated Minnesota Multiphasic Personality Inventory (MMPI) scores on the hysteria (Hy) scale are reported in several forms of pain. Previous results were possibly biased by diagnostic heterogeneity (psychogenic, somatic and mixed pain syndromes included in the same index sample) or Hy heterogeneity (failure to differentiate Hy scores into clinically meaningful subscales, such as admission of symptoms [Ad] and denial of symptoms [Dn]). To overcome this drawback, 48 patients diagnosed as having a Diagnostic and Statistical Manual of Mental Disorders, 4th edn, Text Revision (DSM-IV-TR) diagnosis of "pain disorder associated with psychological factors" were compared with 48 patients experiencing somatic pain excluding psychological factors, and 42 somatic controls without pain. MMPI Hy and hypochondriasis (Hs) scores were significantly higher in the pain disorder group than in control groups, who scored similarly. MMPI correction (K) scores and Dn scores were similar in the three groups, whereas Ad was significantly higher in the pain disorder group and lower and similar in the two control groups, respectively. In the pain disorder group, Ad and Dn were negatively correlated, whereas in control groups they were unrelated. These findings suggest that whereas a pattern of high Hs and Hy scores together with a normal K score might characterize patients with a pain disorder associated with psychological factors, elevated Hy scores per se do not indicate hysterical traits. In the pain disorder group, elevated Hy scores reflected the Ad subscale alone, indicating a strikingly high frequency of distressing somatic symptoms. They tend not to repress or deny the emotional malaise linked to symptoms, as the hysterical construct expects. The pain disorder designation should be considered a nonhysterical form of somatization.

  15. Klatring i trær og hyttebygging: - om barns lek og lekesteder ute

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    Merete Lund Fasting

    2015-07-01

    Full Text Available Abstract: This article describes 10 year old children`s play in nature during school hours. However, my result does equally reflect on children in kindergarden as well. Observation and conversation was used as methods as well as pictures. The children’s play in the trees and building huts was conducted in groups, and their communication was nonverbal with each other and with the nature. However; the girls reveal that they enjoy their conversations while being in the tree. The children often play at the same place over and over. This is significant to the evolution of the play and the children’s communication with their places in nature.Sammendrag: Denne artikkelen omhandler 10 år gamle barns lek på natursteder i skoletida. Selv om studien omhandler 10 åringer så kan kunnskapen den frembringer også være viktig for å forstå barnehagebarns lek og tilknytning til sine lekesteder i barnehagen. Metodene som ble brukt for å undersøke barnas lek var observasjoner og samtaler med barna, i tillegg til fotografier. Barnas lek i trærne og i hyttebyggingen karakteriseres ved at de er flere sammen, og barna har en kroppslig dialog med hverandre og omgivelsene i leken. Barna snakker i liten grad sammen om leken og hvordan de skal leke; deres kommunikasjon er hovedsakelig nonverbal. Men når jentene sitter i treet forteller de meg at de liker å sitte og snakke. Barna leker på steder hvor de har vært mye før, og dette har en betydning for barnas lek og barnas kommunikasjon med deres steder.

  16. Confiabilidade estrutural de uma ponte protendida de madeira considerando o tráfego real

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    Andrés Batista Cheung

    Full Text Available Resumo As pontes protendidas de madeira consistem em sistemas estruturais alternativos, mais leves do que as pontes tradicionais, e apresentam grande rigidez e facilidade de montagem. No Brasil a primeira ponte protendida de madeira foi projetada e construída sobre o Rio Monjolinho, em São Carlos, SP. A confiabilidade desse tipo de estrutura é um dos pontos de maior preocupação técnica, embora essa forma de avaliação ainda não seja utilizada em projetos de pontes de madeira. Este trabalho objetivou avaliar a confiabilidade estrutural do sistema laminado protendido de madeira da ponte projetada sobre o Rio Monjolinho, com foco especial na resistência à flexão e na perda de protensão do sistema, considerando-se para tanto um conjunto variado de trens-tipo. O tabuleiro foi avaliado como uma viga equivalente, baseado no comportamento de placa ortotrópica, e para verificar a segurança da ponte um estudo de confiabilidade foi realizado considerando ações reais obtidas por meio dos dados da concessionária Centrovias. Os resultados das análises de confiabilidade revelaram que a ponte protendida de madeira apresentou índices de confiabilidade compatíveis para a maioria dos carregamentos simulados do tráfego, embora para alguns tipos de caminhões a ponte tenha apresentado índices de confiabilidade abaixo do recomendado pelas normas internacionais.

  17. Genome Sequencing and Comparative Analysis of the Biocontrol Agent Trichoderma harzianum sensu stricto TR274

    Energy Technology Data Exchange (ETDEWEB)

    Steindorff, Andrei S.; Noronha, Elilane F.; Ulhoa, Cirano J.; Kuo, Alan; Salamov, Asaf A.; Haridas, Sajeet; Riley, Robert W.; Druzhinina, Irina S.; Kubicek, Christian P.; Grigoriev, Igor V.

    2015-03-17

    Biological control is a complex process which requires many mechanisms and a high diversity of biochemical pathways. The species of Trichoderma harzianum are well known for their biocontrol activity against many plant pathogens. To gain new insights into the biocontrol mechanism used by T. harzianum, we sequenced the isolate TR274 genome using Illumina. The assembly was performed using AllPaths-LG with a maximum coverage of 100x. The assembly resulted in 2282 contigs with a N50 of 37033bp. The genome size generated was 40.8 Mb and the GC content was 47.7%, similar to other Trichoderma genomes. Using the JGI Annotation Pipeline we predicted 13,932 genes with a high transcriptome support. CEGMA tests suggested 100% genome completeness and 97.9% of RNA-SEQ reads were mapped to the genome. The phylogenetic comparison using orthologous proteins with all Trichoderma genomes sequenced at JGI, corroborates the Trichoderma (T. asperellum and T. atroviride), Longibrachiatum (T. reesei and T. longibrachiatum) and Pachibasium (T. harzianum and T. virens) section division described previously. The comparison between two Trichoderma harzianum species suggests a high genome similarity but some strain-specific expansions. Analyses of the secondary metabolites, CAZymes, transporters, proteases, transcription factors were performed. The Pachybasium section expanded virtually all categories analyzed compared with the other sections, specially Longibrachiatum section, that shows a clear contraction. These results suggests that these proteins families have an important role in their respective phenotypes. Future analysis will improve the understanding of this complex genus and give some insights about its lifestyle and the interactions with the environment.

  18. Comportamento no trânsito entre estudantes de medicina Traffic behavior of medical students

    Directory of Open Access Journals (Sweden)

    Daniel Colicchio

    2010-01-01

    Full Text Available OBJETIVOS: Estudar o comportamento de estudantes de medicina em relação ao trânsito, comparando os padrões atuais com aqueles observados em estudo realizado anteriormente na mesma instituição. MÉTODOS: Foram aplicados questionários padronizados em uma amostra de estudantes regularmente matriculados no curso médico da Faculdade de Medicina de Ribeirão Preto, objetivando coletar informações demográficas, socioeconômicas e referentes ao comportamento no trânsito e envolvimento em acidentes. Esses resultados foram comparados com os obtidos em investigação semelhante, realizada em 1997. RESULTADOS: Foram estudados 354 alunos em 2008 e 377 em 1997. Do total, 431 (59% já haviam dirigido logo após a ingestão de álcool, sendo que, desses, 21,5% em condições de intensa alcoolização. Participação em rachas foi referida por 10,5% dos participantes, com diferença marcante entre os sexos (12,5% entre homens e 3,4% em mulheres. Envolvimento em acidentes com vítimas, fatais ou não, foi referido por 19,2% dos participantes. Esses percentuais atingiram 31,1% entre os que já dirigiram intensamente alcoolizados e 42,9% entre os que participaram de rachas. O estudo de 2008 evidenciou maior uso de capacete e de cinto de segurança em meio urbano e redução de uso de bebidas alcoólicas antes de dirigir. Por outro lado, mostrou redução de respeito contínuo à sinalização de semáforos. CONCLUSÃO: Comportamentos de risco no trânsito fazem-se presentes com elevada frequência entre os participantes, estando diretamente relacionados com o envolvimento em acidentes que provocam vítimas. Visto ser essa uma parcela populacional diferenciada, com conhecimento e contato direto com as consequências desses acidentes, esperar-se-ia uma menor presença de comportamentos de elevado risco. As informações oriundas desse trabalho devem conduzir a uma reflexão por parte da comunidade acadêmica com vistas à introdução de programas

  19. Chimeric bispecific OC/TR monoclonal antibody mediates lysis of tumor cells expressing the folate-binding protein (MOv18) and displays decreased immunogenicity in patients

    NARCIS (Netherlands)

    Luiten, R. M.; Warnaar, S. O.; Sanborn, D.; Lamers, C. H.; Bolhuis, R. L.; Litvinov, S. V.; Zurawski, V. R.; Coney, L. R.

    1997-01-01

    The bispecific OC/TR monoclonal antibody (mAb) cross-links the CD3 molecule on T cells with the human folate-binding protein (FBP), which is highly expressed on nonmucinous ovarian carcinomas. Clinical trials of patients with ovarian carcinoma with the OC/TR mAb have shown some complete and partial

  20. Investigation of a solar heating system for space heating and domestic hot water supply for Sol&Træ A.m.b.a

    DEFF Research Database (Denmark)

    Vejen, Niels Kristian

    1999-01-01

    A solar heating system for space heating and domestic hot water supply from "Sol&Træ A.m.b.a." was tested in a laboratory test facility.......A solar heating system for space heating and domestic hot water supply from "Sol&Træ A.m.b.a." was tested in a laboratory test facility....

  1. The potential of chitosan in enhancing peptide and protein absorption across the TR146 cell culture model-an in vitro model of the buccal epithelium

    DEFF Research Database (Denmark)

    Portero, Ana; Remuñán-López, Carmen; Nielsen, Hanne Mørck

    2002-01-01

    To investigate the potential of chitosan (CS) to enhance buccal peptide and protein absorption, the TR146 cell culture model, a model of the buccal epithelium, was used.......To investigate the potential of chitosan (CS) to enhance buccal peptide and protein absorption, the TR146 cell culture model, a model of the buccal epithelium, was used....

  2. Uniprindi büroo- ja trükikojahoone : edu peatänavatest, Uniprindi trükikojast ning geneerilisest arhitektuurist = Success from Main Streets, Uniprint Printing Plant, and Generic Architecture / Veljo Kaasik

    Index Scriptorium Estoniae

    Kaasik, Veljo

    2000-01-01

    Pärnu mnt. ristmiku juurde Tallinnas R. Puusepa arhitektibüroo poolt trükikojale Uniprint projekteeritud büroo-tootmishoonest. Arhitektid Raivo Puusepp, Krista Väärtnõu. Konstruktsioonid: Projektbüroo Teinos, Civen OÜ. Projekt 1999-2000, hoone valmis 2000. Peatänavaid ääristava hoonestuse kiirest muundumisest. 9 ill.: korruste plaanid, lõiked, vaated (joon.); välisvaated (foto)

  3. Elementos do trágico em Eça de Queirós: A tragédia da Rua das Flores e Os Maias

    OpenAIRE

    Leal, Luciana Ferreira [UNESP

    2006-01-01

    Esta tese analisa dois romances queirosianos vinculados ao gênero dramático, mais especificamente ao trágico. No primeiro momento, busca-se levar a efeito considerações teóricas acerca do trágico, caracterizando a sua especificidade, tanto na origem, quanto no seu desenvolvimento ulterior. Nesta busca da peculiaridade do sentido do trágico, a atenção volta-se para a evolução do gênero da Antigüidade ao Tempo Cristão, do trágico grego ao trágico moderno. Assim, elementos como Hybris, Antinomia...

  4. A feasibility study concerning the conversion of the TR-2 reactor from using highly enriched uranium to light enriched uranium

    International Nuclear Information System (INIS)

    Aldemir, T.; Turgut, H.M.; Bretscher, M.M.; Snelgrove, L.J.

    1983-01-01

    A study has been made of the feasibility of converting the 5-MW TR-2 reactor at CNAEM to use fuel with uranium enrichment of 3 O 8 -Al fuel meat with a uranium density in the range 2.3 to 3.0 g/cm 3 in the fuel meat with meat thickness varying between 0.9 and 1.00 mm, the number of plates in the LEU element being reduced from 23 in the HEU element to 19 to 20 to maintain adequate cooling. Fuels within this density range are expected to be commercially available within the next two years. From the results of the study it appears to be feasible to safely operate the TR-2 reactor using LEU fuel without increased fuel cycle costs or decreased performance using U 2 O 8 fuels with densities in the 2.3 to 3.0 gU/cm 3 range. (author)

  5. Poblaciones-Mercancía: Tráfico y trata de mujeres en España

    OpenAIRE

    García Cuesta, Sara; López Sala, Ana María; Hernández Corrochano, Elena; Mena Martínez, Luis

    2011-01-01

    Se trata de la primera publicación que hace la Delegación del Gobierno para la Violencia de Género a fin de ahondar en el fenómeno de la Trata de Seres Humanos con fines de explotación sexual. El estudio refleja la situación en España de las mujeres que han sido víctimas del tráfico y de la trata de seres humanos con fines de explotación sexual, trazando de manera firme la diferencia entre tráfico de personas y trata de mujeres con fines de explotación sexual.

  6. Uso de redes neuronales artificiales para mejorar el tránsito en las vías

    Directory of Open Access Journals (Sweden)

    Edwin Mejía

    2016-11-01

    Full Text Available Este artículo pretende dar una idea de cómo las Redes Neuronales Artificiales (ANNs, una técnica de la Inteligencia Artificial (IA, se puede acoplar a resolver el problema del tráfico en las vías de la ciudad de Riobamba, provincia de Chimborazo, país Ecuador, usando cuatro semáforos estándar, a través de un ejemplo se indica el uso de componentes electrónicos como FPGAs (Field Programmable Gate array y los sensores en este campo, a través de detectar y contar autos puede dar mayor fluidez al tráfico. La vía que mayor cantidad de autos tenga se dará mayor prioridad para la luz verde. Usando el algoritmo de aprendizaje de un Perceptrón Simple.

  7. Adquisición de variables de tráfico vehicular usando visión por computador

    OpenAIRE

    Germán Enrique Urrego; Francisco Carlos Calderón; Alejandro Forero; Julián Armando Quiroga

    2009-01-01

    El conteo de vehículos es una tarea fundamental en los aforos de tráfico, tanto para el diseño de nuevas vías como para el control y la optimización del tráfico urbano. En ciudades como Bogotá, este conteo actualmente se realiza en forma manual, pero puede hacerse automáticamente empleando técnicas de visión por computador. El presente artículo muestra el desarrollo de un algoritmo de detección y seguimiento de vehículos en tiempo real a partir de video, el cual permite el conteo de vehículos...

  8. ETR fuel element shipping container addendum to PR-T-79-011 (TR-466). Internal technical report

    International Nuclear Information System (INIS)

    Smith, M.C.

    1979-01-01

    In July, 1979, EG and G Idaho, Inc. was requested to evaluate the ETR Fuel Element Shipping Container for compliance with existing transport regulations, in order to ship GETR fuel elements from Vallecitos, California to the INEL. Technical report PR-T-79-011 (TR-466), ATR Fuel Element Shipping Container Safety Analysis, was used as a basis for this evaluation. The safety analysis contained in technical report PR-T-79-011 (TR-466) was performed utilizing the ATR, ETR, MTR, and SPERT shipping containers. The report determined the ETR Fuel Element Shipping Container does comply with the existing transport regulations for a Type A quantity, Fissile Class I shipping container. The ETR and GETR fuel elements are essentially identical in physical size, construction, and fissile material content, the analysis documented in this report has determined the shipment of GETR fuel elements in the ETR shipping container to be safe and pose no threat to the public health and safety

  9. Uma Abordagem de Monitoração de Tráfego de Rede utilizando Lógica Difusa

    OpenAIRE

    Silveira, Enio Rovere; Universidade Federal de Santa Catarina; Dantas, M. A.R.; Universidade Federal de Santa Catarina

    2005-01-01

    Neste artigo, apresentamos um trabalho de pesquisa de monitoração de tráfego de rede utilizando uma abordagem de lógica difusa. Nossa contribuição está focada na criação de um protótipo que pudesse ser avaliado em uma configuração real de produção de uma grande organização, utilizando-se de hardware e software existentes na empresa. Resultados experimentais obtidos através de estudos de casos reais no ambiente, indicam o sucesso da abordagem na melhoria da monitoração de tráfego da rede....

  10. O pluralismo da tese dos três mundos de Popper e a crí­tica de Habermas

    Directory of Open Access Journals (Sweden)

    João Batista C. Sieczkowski

    2010-09-01

    Full Text Available Este estudo abordará a tese dos três mundos, TTM, de Karl Popper. A TTM como pluralista e interacionista opõe-se ao monismo e a algumas concepções dualistas. Em uma segunda parte, pretendemos enfocar a crítica de Jürgen Habermas quando tenta aplicar a TTM e o M3 (mundo três na obtençáo de uma justificaçáo da teoria da açáo para a sociologia. Nesta crítica Habermas acaba negligenciando muitos objetivos claros da TTM e do M3 descritos por Popper, principalmente quando náo considera a TTM como uma tese metafísica e como resposta ao problema corpo-mente.

  11. Comparison of DSM-IV-TR and DSM-5 Criteria in Diagnosing Autism Spectrum Disorders in Singapore.

    Science.gov (United States)

    Sung, Min; Goh, Tze Jui; Tan, Bei Lin Joelene; Chan, Jialei Stephanie; Liew, Hwee Sen Alvin

    2018-04-28

    Our study examines the Diagnostic and Statistical Manual-Fifth Edition (DSM-5) and Diagnostic and Statistical Manual-Fourth Edition, Text Revision (DSM-IV-TR) when applied concurrently against the best estimate clinical diagnoses for 110 children (5.1-19.6 years old) referred for diagnostic assessments of Autism Spectrum Disorder (ASD) in a Singaporean outpatient speciality clinic. DSM-IV-TR performed slightly better, yielding sensitivity of 0.946 and specificity of 0.889, compared to DSM-5 (sensitivity = 0.837; specificity = 0.833). When considering the ASD sub-categories, sensitivity ranged from 0.667 to 0.933, and specificity ranged from 0.900 to 0.975. More participants with a PDD-NOS best estimate clinical diagnosis (40%) were misclassified on DSM-5. Merits and weaknesses to both classification systems, and implications for access to services and policy changes are discussed.

  12. Liquid-phase tuning of porous PVDF-TrFE film on flexible substrate for energy harvesting

    Science.gov (United States)

    Chen, Dajing; Chen, Kaina; Brown, Kristopher; Hang, Annie; Zhang, John X. J.

    2017-04-01

    Emerging wearable and implantable biomedical energy harvesting devices demand efficient power conversion, flexible structures, and lightweight construction. This paper presents Polyvinylidene fluoride-trifluoroethylene (PVDF-TrFE) micro-porous structures, which can be tuned to specific mechanical flexibilities and optimized for piezoelectric power conversion. Specifically, the water vapor phase separation method was developed to control microstructure formation, pore diameter, porosity, and mechanical flexibility. Furthermore, we investigated the effects of the piezoelectric layer to supporting layer Young's modulus ratio, through using both analytical calculation and experimentation. Both structure flexibility and stress-induced voltage were considered in the analyses. Specification of electromechanical coupling efficiency, made possible by carefully designed three-dimensional porous structures, was shown to increase the power output by five-fold relative to uncoupled structures. Therefore, flexible PVDF-TrFE films with tunable microstructures, paired with substrates of different rigidities, provide highly efficient designs of compact piezoelectric energy generating devices.

  13. Analýza tréninku snowboardcrossové reprezentace České republiky

    OpenAIRE

    Řehák, Tomáš

    2012-01-01

    Title: Analysis of training program in the Czech snowboardcross representation Objectives: The main objective of this thesis is to describe an annual training cycle of the Czech snowboardcross representation. Sub-objective is to analyze the individual periods of characteristic sport's preparation. Methods: In our work we used the method of involved observation, analysis, survey, interview with the instructions and informal interview. During the observation of competitor's behavior in their tr...

  14. Rasterelektronenmikroskopische und immunhistochemische Untersuchungen am Eileiter vom Schwein während Zyklus und Trächtigkeit

    OpenAIRE

    Mayer, Judith

    2008-01-01

    In der vorliegenden Arbeit wurden zum einen mit Hilfe des Rasterelektronenmikroskops die morphologischen Veränderungen des Eileiterepithels und zum anderen die Expression hypophysärer wachstums- und proliferationsfördernder Hormone und ihrer Rezeptoren immunhistochemisch und mit der Reverse Transkriptase (RT)-PCR sowohl im Verlauf des Zyklus als auch der Trächtigkeit analysiert. Hierfür wurden, von 24 Schweinen der Deutschen Landrasse, die drei Abschnitte des Eileiters (Infundibulum, Ampulle,...

  15. Mudando o debate sobre o tráfico de mulheres Shifting the debate on the traffic of women

    Directory of Open Access Journals (Sweden)

    Kamala Kempadoo

    2005-12-01

    Full Text Available Neste texto apresento perspectivas e abordagens importantes no debate internacional sobre o tráfico de pessoas, e sublinho alguns dos principais pontos de crítica sobre o referencial contemporâneo hegemônico, pontos esses articulados através de projetos de pesquisa-ação e de intervenções contra o tráfico nas bases da sociedade. Argumento que, a despeito de mudanças substanciais no entendimento global sobre o tráfico, fortemente influenciadas por dois discursos feministas claramente diferentes (feminismo radical e feminismo transnacional, muito do que se busca hoje em nome de uma guerra ao tráfico tem conseqüências problemáticas para comunidades pobres ao redor do mundo, e tem implicações em termos de raça e gênero. As políticas norte-americanas são aqui trazidas ao debate para ilustrar algumas dessas tendências.In this text I present central perspectives and approaches in the international debate about the trafficking of persons, and highlight some of the main points of critique about the contemporary hegemonic framework that are articulated through action-research projects and grassroots anti-trafficking interventions. I argue that despite substantial shifts in global understandings about trafficking, which are heavily influenced by two distinctly different feminist discourses (radical feminism and transnational feminism, today much of what is pursued in the name of a war on trafficking has troubling consequences for poor communities around the world, and has gendered and racialized implications. US anti-trafficking policies are drawn upon here to illustrate some of these tendencies.

  16. ReTrOS: a MATLAB toolbox for reconstructing transcriptional activity from gene and protein expression data.

    Science.gov (United States)

    Minas, Giorgos; Momiji, Hiroshi; Jenkins, Dafyd J; Costa, Maria J; Rand, David A; Finkenstädt, Bärbel

    2017-06-26

    Given the development of high-throughput experimental techniques, an increasing number of whole genome transcription profiling time series data sets, with good temporal resolution, are becoming available to researchers. The ReTrOS toolbox (Reconstructing Transcription Open Software) provides MATLAB-based implementations of two related methods, namely ReTrOS-Smooth and ReTrOS-Switch, for reconstructing the temporal transcriptional activity profile of a gene from given mRNA expression time series or protein reporter time series. The methods are based on fitting a differential equation model incorporating the processes of transcription, translation and degradation. The toolbox provides a framework for model fitting along with statistical analyses of the model with a graphical interface and model visualisation. We highlight several applications of the toolbox, including the reconstruction of the temporal cascade of transcriptional activity inferred from mRNA expression data and protein reporter data in the core circadian clock in Arabidopsis thaliana, and how such reconstructed transcription profiles can be used to study the effects of different cell lines and conditions. The ReTrOS toolbox allows users to analyse gene and/or protein expression time series where, with appropriate formulation of prior information about a minimum of kinetic parameters, in particular rates of degradation, users are able to infer timings of changes in transcriptional activity. Data from any organism and obtained from a range of technologies can be used as input due to the flexible and generic nature of the model and implementation. The output from this software provides a useful analysis of time series data and can be incorporated into further modelling approaches or in hypothesis generation.

  17. Growing skull hemangioma: first and unique description in a patient with Klippel-Trénaunay-Weber syndrome.

    Science.gov (United States)

    van der Loo, Lars E; Beckervordersandforth, Jan; Colon, Albert J; Schijns, Olaf E M G

    2017-02-01

    We present the first and unique case of a rapid-growing skull hemangioma in a patient with Klippel-Trénaunay-Weber syndrome. This case report provides evidence that not all rapid-growing, osteolytic skull lesions need to have a malignant character but certainly need a histopathological verification. This material offers insight into the list of rare pathological diagnoses in an infrequent syndrome.

  18. Comparison of ICD-10R, DSM-IV-TR and DSM-5 in an Adult Autism Spectrum Disorder Diagnostic Clinic

    Science.gov (United States)

    Wilson, C. Ellie; Gillan, Nicola; Spain, Deborah; Robertson, Dene; Roberts, Gedeon; Murphy, Clodagh M.; Maltezos, Stefanos; Zinkstok, Janneke; Johnston, Katie; Dardani, Christina; Ohlsen, Chris; Deeley, P. Quinton; Craig, Michael; Mendez, Maria A.; Happé, Francesca; Murphy, Declan G. M.

    2013-01-01

    An Autism Spectrum Disorder (ASD) diagnosis is often used to access services. We investigated whether ASD diagnostic outcome varied when DSM-5 was used compared to ICD-10R and DSM-IV-TR in a clinical sample of 150 intellectually able adults. Of those diagnosed with an ASD using ICD-10R, 56% met DSM-5 ASD criteria. A further 19% met DSM-5 (draft)…

  19. TR-PIV measurement of the wake behind a grooved cylinder at low Reynolds number

    Science.gov (United States)

    Liu, Ying Zheng; Shi, Liu Liu; Yu, Jun

    2011-04-01

    A comparative study of the wakes behind cylinders with grooved and smooth surfaces was performed with a view to understand the wake characteristics associated with the adult Saguaro cacti. A low-speed recirculation water channel was established for the experiment; the Reynolds number, based on the free-stream velocity and cylinder diameter (D), was kept at ReD=1500. State-of-the-art time-resolved particle image velocimetry (TR-PIV) was employed to measure a total of 20 480 realizations of the wake field at a frame rate of 250 Hz, enabling a comprehensive view of the time- and phase-averaged wake pattern. In comparison to the wake behind the smooth cylinder, the length of the recirculation zone behind the grooved cylinder was extended by nearly 18.2%, yet the longitudinal velocity fluctuation intensity was considerably weakened. A global view of the peaked spectrum of the longitudinal velocity component revealed that the intermediate region for the grooved cylinder, which approximately corresponds to the transition region where the shear layer vortices interact, merge and shed before the formation of the Karman-like vortex street, was much wider than that for the smooth one. The unsteady events near St=0.3-0.4 were detected in the intermediate region behind the grooved cylinder, but no such events were found in the smooth cylinder system. Although the formation of the Karman-like vortex street was delayed by about 0.6D downstream for the grooved cylinder, no prominent difference in the vortex street region was found in the far wake for both cylinders. The Proper Orthogonal Decomposition (POD) method was used extensively to decompose the vector and swirling strength fields, which gave a close-up view of the vortices in the near wake. The first two POD modes of the swirling strength clarified the spatio-temporal characteristics of the shear layer vortices behind the grooved cylinder. The small-scale vortices superimposed on the shear layers behind the grooved cylinder

  20. Tröger’s Base Ladder Polymer for Membrane-Based Hydrocarbon Separation

    KAUST Repository

    Alhazmi, Abdulrahman

    2017-05-01

    The use of polymeric membranes for natural gas separation has rapidly increased during the past three decades, particularly for carbon dioxide separation from natural gas. Another valuable application is the separation of heavy hydrocarbons from methane (fuel gas conditioning), more importantly for remote area and off-shore applications. A new potential polymeric membrane that might be utilized for natural gas separations is a Tröger’s base ladder polymer (PIM-Trip-TB-2). This glassy polymeric membrane was synthesized by the polymerization reaction of 9, 10-dimethyl-2,6 (7) diaminotriptycene with dimethoxymethane. In this research, the polymer was selected due to its high surface area and highly interconnected microporous structure. Sorption isotherms of nitrogen (N2), oxygen (O¬2), methane (CH4), carbon dioxide (CO2), ethane (C2H6), propane (C3H8), and n-butane (n-C4H10) were measured at 35 °C over a range of pressures using a Hiden Intelligent Gravimetric Analyzer, IGA. The more condensable gases (C2H6, CO2, C3H8, and n-C4H10) showed high solubility due to their high affinity to the polymer matrix. The permeation coefficients were determined for various gases at 35 °C and pressure difference of 5 bar via the constant-pressure/variable-volume method. The PIM-Trip-TB-2 film exhibited high performance for several high-impact applications, such as O2/N2, H2/N2 and H2/CH4. Also, physical aging for several gases was examined by measuring the permeability coefficients at different periods of time. Moreover, a series of mixed-gas permeation tests was performed using 2 vol.% n-C4H10/98 vol.% CH4 and the results showed similar transport characteristics to other microporous polymers with pores of less than 2 nm. The work performed in this research suggested that PIM-Trip-TB-2 is suitable for the separation of: (i) higher hydrocarbons from methane and (ii) small, non-condensable gases such as O2/N2 and H2/CH4.

  1. A mobilidade humana na tríplice fronteira: Peru, Brasil e Colômbia

    Directory of Open Access Journals (Sweden)

    Márcia Maria de Oliveira

    2006-08-01

    Full Text Available OS MOVIMENTOS migratórios nas fronteiras amazônicas ainda são pouco abordados, tanto pela academia quanto pelas instituições que lidam com a temática da mi-gração. Há elementos novos que configuram características peculiares à mobilidade humana na tríplice fronteira Peru-Colômbia-Brasil que merecem uma abordagem mais profunda do ponto de vista dos estudos migratórios. Atualmente, há fluxos conside-ráveis de migração internacional nessa região adentrando na fronteira brasileira, desafiando o Estado brasileiro a implementar uma política migratória que consiga lidar com fenômenos, tais como a presença de peruanos em situação irregular em território brasileiro, a mobilidade dos povos indígenas nas regiões de fronteira e ainda, mais recentemente, a entrada crescente de colombianos desplazados pela guerrilha interna que pedem refúgio ao Estado brasileiro.THE MIGRATORY mobility in the Amazonian borders is less than enough investigated, neither by the academy nor by the institutions that deal with the migration question. There are new elements that depict peculiar characteristics to the human mobility in the triple border of Peru, Colombia and Brazil, that deserve a deeper investigation from the view point of the migratory studies. At the moment, it has conside-rable flows of international migration in this region moving in the Brazilian border, challenging the Brazilian State to implement a migratory policy that is able to deal with the phenomena such as the presence of Peruvians in an irregular situation in Brazilian territory, the mobility of the indigenous peoples in the border regions and still, more recently, the increasing entrance of the Colombians desplazados through the internal guerrilla who ask for shelter to the Brazilian State.

  2. Recursos disponibles para la protección de mujeres migrantes en tránsito por Tamaulipas

    Directory of Open Access Journals (Sweden)

    Rocío CÁRDENAS-RODRÍGUEZ

    2014-01-01

    Full Text Available La labor del gobierno mexicano en materia de política migratoria es una estrategia para administrar el flujo de migrantes en tránsito rumbo a Estados Unidos, no para salvaguardar su integridad y derechos, menos aún está diseñada para proteger a las mujeres. En esa medida, el interés de este artículo es hacer evidentes los escasos recursos de protección disponibles para migrantes y la ausencia de perspectiva de género en los recursos de apoyo para mujeres en tránsito por México. A través de entrevistas a autoridades y organismos sociales en la frontera de Tamaulipas y con base en el enfoque del modelo ecológico, se evaluaron los recursos de la política pública mexicana como elementos amortiguadores para los migrantes, frente a riesgos y elementos de vulnerabilidad de la mujer en tránsito.

  3. [Clinical usefulness of IDEA and CARS: concordance with DSM-IV-TR in children and adolescents with suspicion of PDD].

    Science.gov (United States)

    García-López, C; Narbona, J

    2014-02-01

    Observational scales are useful to estimate the severity of symptoms in PDD as well as to monitor their evolution. a) To analyze the concordance between diagnoses based on the Autism Spectrum Inventory (Inventario del Espectro Autista, IDEA)) and the Childhood Autism Rating Scale (CARS), compared to DSM-IV-TR criteria, in subjects with a suspicion of pervasive developmental disorders (PDD), and b) to study the discrimination power of both scales to differentiate between a clinical diagnosis situated in the autism spectrum. Fifty-six children and adolescents, between 2 and 20 years-old, who attended our Neuropediatric Unit due to suspicion of PDD. Independently, two clinicians evaluated the presence of PDD symptoms; one of them according to DSM-IV-TR criteria and the other one based on the application of IDEA and CARS. The concordance of IDEA and CARS when compared to DSM-IV-TR classification was 73 and 82%, respectively, with a sensitivity of 1 and 0,83 and a specificity of 0,61 and 0,82, respectively. Both scales correctly discriminated between autistic disorder and other clinical diagnoses. Both IDEA and CARS are useful instruments to detect and monitor autism symptoms in the context of routine clinical practice. Copyright © 2012 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.

  4. Control y simulación de tráfico urbano en Colombia: Estado del arte

    Directory of Open Access Journals (Sweden)

    Daniel Robles

    2009-05-01

    Full Text Available Las condiciones actuales de la movilidad en Colombia generan interrogantes acerca de qué tan apropiadas son las estrategias de control de tráfico aplicadas en las redes urbanas del país. Con esto en mente, se plantea una revisión de las estrategias de control y plataformas de simulación de sistemas de tráfico más utilizadas en Colombia y en otras partes del mundo; con el propósito de caracterizar el nivel de desarrollo del país en el estudio e implementación de estrategias de control de tráfico urbano y, posteriormente, formular propuestas orientadas hacia la mejora de la movilidad urbana en el país./ The current mobility conditions in Colombia give place to questions about the suitability of the traffic control strategies applied on the Colombian urban networks. Therefore, a review of the control strategies and simulation platforms used in Colombia and around the world is shown. This is done to characterize the level of development of the country, in terms of research and implementation of such control strategies and, furthermore, to formulate proposals oriented towards the improvement of the Colombian urban mobility.

  5. Neurocriptococose na infância: relato de três casos na primeira década de vida

    Directory of Open Access Journals (Sweden)

    Maria Helena Fontana

    1987-12-01

    Full Text Available Os autores relatam três casos de neurocriptococose em crianças na primeira década de vida, no Estado do Rio Grande do Sul. O diagnóstico foi estabelecido pelo encontro do fungo Cryptococcus neoformans no líquido céfalo-raquidlano por exame direto com tinta da China e cultura em meio de Sabouraud. As formas de instalação da síndrome neurológica foram aguda, subaguda e crônica. Síndrome de hipertensão intracraniana e hidrocefalia foram complicações observadas durante a evolução da doença, sendo necessária a instalação de derivação ventrículo-peritonial em um caso. Desnutrição foi o processo mórbido associado nos três casos e infecção pelo bacilo da tuberculose em um caso. Terapia específica foi administrada aos três pacientes. Um paciente evoluiu para cura e dois evoluíram para óbito.

  6. Adquisición de variables de tráfico vehicular usando visión por computador

    Directory of Open Access Journals (Sweden)

    Germán Enrique Urrego

    2009-11-01

    Full Text Available El conteo de vehículos es una tarea fundamental en los aforos de tráfico, tanto para el diseño de nuevas vías como para el control y la optimización del tráfico urbano. En ciudades como Bogotá, este conteo actualmente se realiza en forma manual, pero puede hacerse automáticamente empleando técnicas de visión por computador. El presente artículo muestra el desarrollo de un algoritmo de detección y seguimiento de vehículos en tiempo real a partir de video, el cual permite el conteo de vehículos en la vía y la estimación del volumen de tráfico o velocidad promedio./The count of vehicles is a key task in traffic gauging, as it provides information for designing new roads, and for the control and optimization of urban traffic. Nowadays in cities like Bogota, vehicle counting is done manually, but it can also be done automatically using computer vision techniques. This article presents the development of an algorithm for detecting and tracking vehicles in real time from video. The algorithm allows to count vehicles on the road and to estimate traffic volume or average speed.

  7. Três análises de linguagem no autismo Three language analysis in autism

    Directory of Open Access Journals (Sweden)

    Michele Paula Moro

    2011-10-01

    Full Text Available TEMA: Linguagem no Autismo. OBJETIVOS: analisar, comparativamente, dados de linguagem obtidos por meio de dois protocolos, um da interação mãe-criança e outro de atos comunicativos da criança entre si e com a análise dialógica da díade mãe-filho. Outro objetivo foi discutir as implicações de tais análises para o planejamento terapêutico. MÉTODO: a amostra constou de três sujeitos na faixa etária de 2 anos e 1 mês a 4 anos e 6 meses, com diagnóstico de distúrbio de linguagem secundário ao espectro autístico. A coleta foi realizada por meio da filmagem de sessões de interação lúdica, de 30 minutos, dos sujeitos com suas mães. Os procedimentos de análise foram: a transcrição das filmagens, conferência das mesmas, aplicação de dois protocolos, um de análise da interação mãe-filho e outro de comportamentos comunicativos da criança, e uma análise qualitativa da atividade dialógica da díade. RESULTADOS: Os resultados do protocolo de interação mãe-filho demonstraram freqüência similar de categorias dos comportamentos das três mães, com elevado número de perguntas e de diretividade intrusiva. No mesmo protocolo, as crianças demonstraram brincar exploratório e funcional, estereotipias verbais e não verbais, fato também observado no protocolo de pragmática. O protocolo de interação permite observar melhor que os comportamentos infantis e maternos possuem relações, mas apenas a análise qualitativa possibilita identificar a natureza dialética de tais relações. CONCLUSÃO: O protocolo que analisa a interação provê informações fundamentais ao planejamento terapêutico, adicionais ao protocolo de foco exclusivo no conhecimento pragmático do sujeito. Aquele protocolo, em conjunto com a análise qualitativa, permite uma seleção mais qualificada das estratégias de intervenção em cada caso.BACKGROUND: Language in autism. PURPOSE: the data obtained through two protocols and also from the

  8. TrMADS3, a new MADS-box gene, from a perennial species Taihangia rupestris (Rosaceae) is upregulated by cold and experiences seasonal fluctuation in expression level.

    Science.gov (United States)

    Du, Xiaoqiu; Xiao, Qiying; Zhao, Ran; Wu, Feng; Xu, Qijiang; Chong, Kang; Meng, Zheng

    2008-06-01

    In many temperate perennial plants, floral transition is initiated in the first growth season but the development of flower is arrested during the winter to ensure production of mature flowers in the next spring. The molecular mechanisms of the process remain poorly understood with few well-characterized regulatory genes. Here, a MADS-box gene, named as TrMADS3, was isolated from the overwintering inflorescences of Taihangia rupestris, a temperate perennial in the rose family. Phylogenetic analysis reveals that TrMADS3 is more closely related to the homologs of the FLOWERING LOCUS C lineage than to any of the other MIKC-type MADS-box lineages known from Arabidopsis. The TrMADS3 transcripts are extensively distributed in inflorescences, roots, and leaves during the winter. In controlled conditions, the TrMADS3 expression level is upregulated by a chilling exposure for 1 to 2 weeks and remains high for a longer period of time in warm conditions after cold treatment. In situ hybridization reveals that TrMADS3 is predominantly expressed in the vegetative and reproductive meristems. Ectopic expression of TrMADS3 in Arabidopsis promotes seed germination on the media containing relatively high NaCl or mannitol concentrations. These data indicate that TrMADS3 in a perennial species might have its role in both vegetative and reproductive meristems in response to cold.

  9. Tríplice artrodese na paralisia cerebral Triple arthrodesis in cerebral palsy

    Directory of Open Access Journals (Sweden)

    Kotoe Umeda

    2010-01-01

    Full Text Available OBJETIVOS: Avaliar o resultados clínicos díplice artrodese em portadores de paralisia cerebral espástica, verificar a correspondência entre os resultados e a escala AOFAS e os ângulos nos períodos pré e pós-operatórios. MÉTODOS: Entre 1985 e 2005, foram avaliados 34 pacientes (40 pés submetidos a tríplice artrodese do pé, com acompanhamento médio de 91 meses, quanto a satisfação e dor, apoio plantígrado, deformidade residual e o arco de movimento do tornozelo e escala AOFAS. Foram avaliadas artrose de tornozelo, pseudoartrose das articulações e medidos os ângulos: talocalcâneo, talo-primeiro metatarsiano (APM e tíbio-talar, e talocalcâneos (ATC e o calcâneo-solo (ACS. RESULTADOS: Obtivemos bons resultados em 32,4% dos casos e regulares em 44,1%. 85,3% dos pacientes estavam satisfeitos; 88,2% tinham apoio plantígrado. Houve 33,3% de resultados bons pela escala AOFAS e 24,2% regulares. Na radiografia com incidência ântero-posterior, o APM apresentou melhora em média de 15º; no ACS, na incidência em perfil, melhora de 7º. No ATC, nas duas incidências, houve melhora de 1º. CONCLUSÕES: A triplice artrodese corrige ou melhora as deformidades, com grau de satisfação elevada, dando ao paciente pés plantígrados. A escala AOFAS teve fraca concordância com o resultado. Os APM e ACS foram os mais sensíveis na avaliação do procedimento cirúrgico.OBJECTIVE: To demonstrate the clinical results of triple arthrodesis in Cerebral Palsy patients and determine whether there is any correspondence between the results and the AOFAS scale, and changes in radiographic angles between the pre- and postoperative periods. METHODS: Between 1985 and 2005, thirty-four patients (40 feet were submitted to triple arthrodesis of the foot, with an average follow-up time of ninety-one months. The evaluation consisted of the patient's satisfaction and the presence of pain, plantigrade support, residual deformity, range of movement of the

  10. Antecedentes y perspectivas de la actividad bufalina en el trópico

    Directory of Open Access Journals (Sweden)

    Alina Mitat Valdés

    2011-11-01

    y para que los gobiernos se involucren en programas que posibiliten, a partir de esta especie, contribuir a mitigar la pobreza y el desarrollo rural local.En este artículo se expresarán algunas consideraciones sobre los antecedentes y perspectivas de la crianza de los búfalos de agua en el trópico, para poder discutiraciertos y desaciertos, así como encontrar las mejores alternativas que nos permitan obtener, altos resultados productivos sin dañar el entorno, logrando incrementar los conocimientos sobre la especie y la coordinación entre las instituciones responsabilizadas con el trabajo en el ecosistema centroamericano.

  11. Estudio del tráfico de las carreteras de la Diputació de Barcelona en la comarca del Garraf

    OpenAIRE

    Bengoetxea Artetxe, Andoni

    2017-01-01

    En este trabajo se seleccionarán varias carreteras ubicadas en la comarca del Garraf de titularidad de la Diputación de Barcelona y cuyo tráfico sea significativo. Se escogerán carreteras convencionales de dos carriles que carezcan de las características de trazado óptimas para la circulación. El objetivo de este trabajo es el de estudiar el tráfico actual y futuro en estas carreteras para saber si existen o existirán problemas de tráfico, así como proponer posibles medidas para solventar dic...

  12. Estructura trófica de los copépodos pelágicos en el Océano Pacifico Oriental Tropical

    OpenAIRE

    López Ibarra, Gladis Angélica

    2008-01-01

    Gran parte de la productividad secundaria marina es aportada por los copépodos, estos destacan dentro del zooplancton marino por su diversidad y abundancia, puede llegar a constituir un 80 % de la biomasa zooplanctonica. Probablemente el principal papel ecológico de esta comunidad es la transferencia de energía entre los niveles tróficos primarios y los sucesivos en las redes tróficas. En este estudio se analizó la estructura trófica de la comunidad de copépodos pelágicos en el Océano Pacifi...

  13. Análisis funcional de la red trófica de Bahía Magdalena Baja California Sur, México

    OpenAIRE

    Cruz-Escalona,Víctor H; Morales-Zárate,María V; Navia,Andrés F; Rguez-Baron,Juan M; del Monte-Luna,Pablo

    2013-01-01

    El objetivo del presente estudio fue desarrollar un modelo trófico (ECOPATH con ECOSIM) para caracterizar la estructura y función de la trama alimentaria de Bahía Magdalena. El modelo consta de 24 grupos funcionales, siendo dominado por grupos de niveles tróficos secundarios y terciarios, que generan un tercio de los flujos de biomasa total. Los flujos totales del sistema y la eficiencia de transferencia promedio entre niveles tróficos, encajan bien en el rango reportado para otros ecosistema...

  14. Copepod parasites of Curimatella lepidura (Characiformes, Curimatidae from the Três Marias Reservoir, Brazil Copépodes parasitos de Curimatella lepidura (Characiformes, Curimatidae do reservatório de Três Marias, Brasil

    Directory of Open Access Journals (Sweden)

    M.C. Albuquerque

    2008-10-01

    Full Text Available Copépodes ergasilídeos coletados nas brânquias de Curimatella lepidura do reservatório de Três Marias, alto rio São Francisco, Minas Gerais, Brasil e identificados como Miracetyma etimaruya e Ergasilus sp., constituem o primeiro registro de parasitos nesse peixe forrageiro e endêmico. A ocorrência foi independente do sexo e do tamanho dos peixes. A distribuição geográfica conhecida das espécies de Miracetyma Malta, 1993, restrita à bacia do rio Amazonas, é ampliada neste estudo para a bacia do rio São Francisco.

  15. Cross check of the new economic and mass balance feature of the fuel cycle scenario code TR-EVOL

    International Nuclear Information System (INIS)

    Merino-Rodriguez, I.; Garcia-Martinez, M.; Alvarez-Velarde, F.; Lopez, D.

    2016-01-01

    Versatile computational tools with up to date capabilities are needed to assess current nuclear fuel cycles or the transition from the current status of the fuel cycle to the more advanced and sustainable ones. The TR-EVOL module, that is devoted to fuel cycle mass balance, simulates diverse nuclear power plants (PWR, SFR, ADS, etc.), having possibly different types of fuels (UO_2, MOX, etc.), and the associated fuel cycle facilities (enrichment, fuel fabrication, processing, interim storage, waste storage, geological disposal). This work is intended to cross check the new capabilities of the fuel cycle scenario code TR-EVOL.This process has been divided in 2 stages. The first stage is dedicated to check the improvements in the nuclear fuel mass balance estimation using the available data for the Spanish nuclear fuel cycle. The second stage has been focused in verifying the validity of the TR-EVOL economic module, comparing results to data published by the ARCAS EU project. A specific analysis was required to evaluate the back-end cost. Data published by the waste management responsible institutions was used for the validation of the methodology. Results were highly satisfactory for both stages. In particular, the economic assessment provides a difference smaller than 3% regarding results published by the ARCAS project (NRG estimations). Furthermore, concerning the back-end cost, results are highly acceptable (7% difference for a final disposal in a once-through scenario and around 11% for a final disposal in a reprocessing strategy) given the significant uncertainties involved in design concepts and related unit costs. (authors)

  16. One-pot facile synthesis of 4-amino-1,8-naphthalimide derived Tröger's bases via a nucleophilic displacement approach.

    Science.gov (United States)

    Shanmugaraju, Sankarasekaran; McAdams, Deirdre; Pancotti, Francesca; Hawes, Chris S; Veale, Emma B; Kitchen, Jonathan A; Gunnlaugsson, Thorfinnur

    2017-09-13

    We report here a novel one-pot synthetic strategy for the synthesis of a family of N-alkyl-1,8-naphthalimide based Tröger's bases via a nucleophilic substitution reaction of a common 'precursor' (or a 'synthon') N-aryl-1,8-naphthalimide Tröger's base heated at 80 °C in neat aliphatic primary amine, in overall yield of 65-96%. This methodology provides an efficient and one-step facile route to design 1,8-naphthalimide derived Tröger's base structures in analytically pure form without the use of column chromatography purification, that can be used in medicinal chemistry and as supramolecular scaffolds. We also report the formation of the corresponding anhydride, and the crystallographic analysis of two of the resulting products, that of the N-phenyl-4-amino-1,8-naphthalimide and the anhydride derived Tröger's bases.

  17. Estudo da atividade do látex do Croton urucurana Baill. sobre o trânsito gastrintestinal de camundongos

    Directory of Open Access Journals (Sweden)

    Luilma Albuquerque Gurgel

    Full Text Available O presente trabalho tem como propósito avaliar uma possível atividade inibitória do látex do Croton urucurana Baill. sobre o trânsito gastrintestinal de camundongos, bem como tentar esclarecer os possíveis mecanismos de ação envolvidos em sua atividade. Foram utilizados os modelos de trânsito gastrintestinal normal e trânsito gastrintestinal estimulado por fisostigmina em camundongos. Os resultados obtidos mostram que o látex inibiu o trânsito gastrintestinal de camundongos, e, muito embora seu mecanismo de ação ainda não seja claro, seu efeito é independente da participação de mecanismo opióide, colinérgico, α2-adrenérgico ou nitriérgico.

  18. Transmission spectroscopy of the hot Jupiter TrES-3 b: Disproof of an overly large Rayleigh-like feature

    Science.gov (United States)

    Mackebrandt, F.; Mallonn, M.; Ohlert, J. M.; Granzer, T.; Lalitha, S.; García Muñoz, A.; Gibson, N. P.; Lee, J. W.; Sozzetti, A.; Turner, J. D.; Vaňko, M.; Strassmeier, K. G.

    2017-12-01

    Context. Transit events of extrasolar planets offer the opportunity to study the composition of their atmospheres. Previous work on transmission spectroscopy of the close-in gas giant (TrES)-3 b revealed an increase in absorption towards blue wavelengths of very large amplitude in terms of atmospheric pressure scale heights, too large to be explained by Rayleigh-scattering in the planetary atmosphere. Aims: We present a follow-up study of the optical transmission spectrum of the hot Jupiter TrES-3 b to investigate the strong increase in opacity towards short wavelengths found by a previous study. Furthermore, we aim to estimate the effect of stellar spots on the transmission spectrum. Methods: This work uses previously published long slit spectroscopy transit data of the Gran Telescopio Canarias (GTC) and published broad band observations as well as new observations in different bands from the near-UV to the near-IR, for a homogeneous transit light curve analysis. Additionally, a long-term photometric monitoring of the TrES-3 host star was performed. Results: Our newly analysed GTC spectroscopic transit observations show a slope of much lower amplitude than previous studies. We conclude from our results the previously reported increasing signal towards short wavelengths is not intrinsic to the TrES-3 system. Furthermore, the broad band spectrum favours a flat spectrum. Long-term photometric monitoring rules out a significant modification of the transmission spectrum by unocculted star spots. Based on (1) data obtained with the STELLA robotic telescopes in Tenerife, an AIP facility jointly operated by AIP and IAC, (2) observations collected at the German-Spanish Astronomical Center, Calar Alto, jointly operated by the Max-Planck-Institut für Astronomie Heidelberg and the Instituto de Astrofísica de Andalucía (CSIC) and (3) observations made with the Italian Telescopio Nazionale Galileo (TNG) operated on the island of La Palma by the Fundación Galileo Galilei of

  19. SU-F-I-58: Image Quality Comparisons of Different Motion Magnitudes and TR Values in MR-PET

    International Nuclear Information System (INIS)

    Patrick, J; Thompson, R; Tavallaei, M; Drangova, M; Stodilka, R; Gaede, S

    2016-01-01

    Purpose: The aim of this work is to evaluate the accuracy and sensitivity of a respiratory-triggered MR-PET protocol in detecting four different sized lesions at two different magnitudes of motion, with two different TR values, using a novel PET-MR-CT compatible respiratory motion phantom. Methods: The eight-compartment torso phantom was setup adjacent to the motion stage, which moved four spherical compartments (28, 22, 17, 10 mm diameter) in two separate (1 and 2 cm) linear motion profiles, simulating a 3.5 second respiratory cycle. Scans were acquired on a 3T MR-PET system (Biograph mMR; Siemens Medical Solutions, Germany). MR measurements were taken with: 1) Respiratory-triggered T2-weighted turbo spin echo (BLADE) sequence in coronal orientation, and 2) Real-time balanced steady-state gradient echo sequence (TrueFISP) in coronal and sagittal planes. PET was acquired simultaneously with MR. Sphere geometries and motion profiles were measured and compared with ground truths for T2 BLADE-TSE acquisitions and real time TrueFISP images. PET quantification and geometry measurements were taken using standardized uptake values, voxel intensity plots and were compared with known values, and examined alongside MR-based attenuation maps. Contrast and signal-to-noise ratios were also compared for each of the acquisitions as functions of motion range and TR. Results: Comparison of lesion diameters indicate the respiratory triggered T2 BLADE-TSE was able to maintain geometry within −2 mm for 1 cm motion for both TR values, and within −3.1 mm for TR = 2000 ms at 2 cm motion. Sphere measurements in respiratory triggered PET images were accurate within +/− 5 mm for both ranges of motion for 28, 22, and 17 mm diameter spheres. Conclusion: Hybrid MR-PET systems show promise in imaging lung cancer in non-compliant patients, with their ability to acquire both modalities simultaneously. However, MR-based attenuation maps are still susceptible to motion derived artifacts and

  20. Diversidade de formigas epígeas em três ambientes no noroeste do Paraná - Brasil

    OpenAIRE

    Halison Correia Golias

    2008-01-01

    As formigas são insetos que exercercem importante papel como bioindicadores, pragas agrícolas, controle biológico, polinizadores e dispersores de sementes. Este trabalho objetivou conhecer e comparar a diversidade de formigas em três ambientes (fragmento florestal, pomar de laranja e pomar de limão) do noroeste do Paraná. As coletas foram realizadas com armadilhas pitfall, sendo utilizados copos plástico com 7,5 cm de diâmetro por 11,5 cm de altura, enterrados totalmente no, solo. Foram insta...

  1. Estudio computacional de transferencia electrónica intramolecular en tríadas conjugadas ferroceno-puente-aceptor

    OpenAIRE

    García López, Rafaela

    2016-01-01

    En el presente trabajo se analiza, desde el punto de vista teórico a través de cálculos mecanocuánticos, el comportamiento dador del ferroceno, de potencial utilidad en procesos de reconocimiento de cationes metálicos, así como la estabilización de deficiencias electrónicas en  a grupos ferrocenilo. Esto permite el estudio del fenómeno de transferencia electrónica intramolecular en diferentes tríadas ferroceno-puente-aceptor, así como el efecto de la naturaleza y longitud de espaciadores -c...

  2. El delito de tráfico de influencias en la jurisprudencia de la Corte Suprema de Justicia

    OpenAIRE

    Piedrahita Jaramillo, Renán

    2012-01-01

    El presente ensayo está dirigido al estudio desde la jurisprudencia del delito de tráfico de influencias (arts. 411 y 411 A). La justificación del estudio propuesto está dada por la necesidad de mirar la parte especial del Código Penal, en tanto que la mayoría de la doctrina nacional se ha interesado por el estudio de su parte general, recabando en los institutos que conforman el injusto penal y el tipo subjetivo, entre otros temas, sin mirar la necesidad de sentar las bases de interpretación...

  3. CLM4-BeTR, a generic biogeochemical transport and reaction module for CLM4: model development, evaluation, and application

    Directory of Open Access Journals (Sweden)

    J. Y. Tang

    2013-01-01

    Full Text Available To improve regional and global biogeochemistry modeling and climate predictability, we have developed a generic reactive transport module for the land model CLM4 (called CLM4-BeTR (Biogeochemical Transport and Reactions. CLM4-BeTR represents the transport, interactions, and biotic and abiotic transformations of an arbitrary number of tracers (aka chemical species in an arbitrary number of phases (e.g., dissolved, gaseous, sorbed, aggregate. An operator splitting approach was employed and consistent boundary conditions were derived for each modeled sub-process. Aqueous tracer fluxes, associated with hydrological processes such as surface run-on and run-off, belowground drainage, and ice to liquid conversion were also computed consistently with the bulk water fluxes calculated by the soil physics module in CLM4. The transport code was evaluated and found in good agreement with several analytical test cases using a time step of 30 min. The model was then applied at the Harvard Forest site with a representation of depth-dependent belowground biogeochemistry. The results indicated that, at this site, (1 CLM4-BeTR was able to simulate soil–surface CO2 effluxes and soil CO2 profiles accurately; (2 the transient surface CO2 effluxes calculated based on the tracer transport mechanism were in general not equal to the belowground CO2 production rates with the magnitude of the difference being a function of averaging timescale and site conditions: differences were large (−20 ~ 20% on hourly, smaller (−5 ~ 5% at daily timescales, and persisted to the monthly timescales with a smaller magnitude (<4%; (3 losses of CO2 through processes other than surface gas efflux were less than 1% of the overall soil respiration; and (4 the contributions of root respiration and heterotrophic respiration have distinct temporal signals in surface CO2 effluxes and soil CO2 concentrations. The

  4. Comportamento produtivo da videira, cultivar Juliana, sobre três porta-enxertos em diferentes épocas de poda

    Directory of Open Access Journals (Sweden)

    Mara Fernandes Moura

    2011-10-01

    Full Text Available Este trabalho objetivou verificar a influência de três porta-enxertos no comportamento da cultivar Juliana em relação à fenologia, em três épocas de poda e em relação aos caracteres físicos de cachos, de bagas e de engaços, em duas épocas de poda. Os ensaios foram avaliados em Jundiaí-SP, e as podas foram realizadas em 15-08-2007, 22-01-2008 e 16-09-2008. O delineamento experimental foi o em blocos inteiramente casualizados, com parcelas subdivididas, com três repetições, sendo as parcelas representadas pela combinação da cultivar Juliana enxertada sobre os porta-enxertos 'Ripária do Traviú', 'IAC 572' e 'IAC766', e as subparcelas, pelas épocas de poda, que corresponderam a três para os estádios fenológicos e a duas para os caracteres físicos de cachos, bagas e engaço. Não houve diferença entre os porta-enxertos para os estádios fenológicos e para os caracteres físicos de cachos e de bagas, com exceção para massa da matéria fresca de baga e massa fresca de engaço. Maior massa da matéria fresca de engaço foi obtida pela combinação da cultivar Juliana e o porta-enxerto 'IAC 572'. Para as diferentes épocas de poda, foram detectadas diferenças para todos os estádios fenológicos, havendo interação entre porta-enxerto e época de poda para os estádios E1 - período da poda ao início da brotação; E2 - período da poda ao início do florescimento, e E5 - período da poda ao início da colheita.

  5. El tráfico de órganos en Brasil: Civilconstitucional enderece contra la Mercantilización persona

    Directory of Open Access Journals (Sweden)

    Mara Conceição Vieira de Oliveira

    2016-06-01

    Full Text Available Pese haya regulación en el sistema jurídico brasileño, el Tráfico de órganos es problema serio, y medidas de prevención son poco discutidas y/o presentadas. La atrocidad del cri- men se vuelve poco creíble ante la sociedad, en la cual muchos entienden el tráfico de ór- ganos sólo como más una leyenda urbana. Este estudio cuestiona: ¿Cuál la efectividad de la regulación de la dignidad de la persona humana, cuando el cuerpo asume valor de “cosa”?, es decir, ¿Cuánto cuesta una persona o parte suya cuando transformada en producto en una sociedad de mercado? ¿Cuáles los límites jurídicos y morales son violados cuando un órgano está puesto a la venta? De esta manera, se objetiva, aquí, describir el principio de la dignidad de la persona humana y su efectividad en relación a este crimen, señalando el incumplimiento del Código Civil Brasileiro. Para eso, el procedimiento metodológico ele- gido se orientará por la investigación teórico bibliográfica, al realizar lecturas legislativas y doctrinarias; lectura crítica filosófica con Michael Sandel sobre la moralidad del mercado; y recopilación de datos sobre la base de la CPI del Tráfico de órganos – “CPIORGAO”. Los resultados obtenidos, hasta el momento actual, presentan recopilación teórico bibliográfi- ca; aún no se realizó análisis aplicada a los casos específicos citados por la comisión, a pesar de que puedan venir a ser estudiados en otras etapas del desarrollo de la investigación. La temática de este artículo, al relacionar la problemática del tráfico de órganos, la dignidad de la persona humana y la mercantilización del cuerpo, contribuye para el tema del evento: - Participación, Democracia y Ciudadanía en la perspectiva del Derecho Iberoameri- cano -, una vez que nuestro grupo de investigación también entiende la cuestión en este escenario de creciente y complejo proceso de globalización.

  6. Modelo origen destino para estimar el flujo de tráfico usando algoritmos genéticos

    OpenAIRE

    Aldás S., Milton R.; Flores C., Marco J.; Universidad de Cuenca; Dirección de Investigación de la Universidad de Cuenca; DIUC

    2014-01-01

    En este trabajo se ha desarrollado un nuevo método basado en Inteligencia Artificial para resolver un problema del matriz origen-destino (O-D) aplicado al caso de una red de tráfico vehicular en la ciudad de Ambato. El método implementado, basado en algoritmos genéticos (AG), resuelve el problema de minimización asociado al problema de matriz O-D. Para validar la técnica, se ha utilizado una red vial correspondiente a la zona del Mercado Modelo en la ciudad de Ambato, que es una zona de alta ...

  7. Estimulantes tipo-anfetamínicos : uma abordagem no trânsito, analítica e forense

    OpenAIRE

    Kristiane de Cássia Mariotti

    2013-01-01

    A utilização de substâncias estimulantes tipo-anfetamínicos (ATS) por motoristas com objetivo de aumentar o tempo de vigília é um conhecido problema nacional com consequências sociais e legais. A dietilpropiona (DIE) e o femproporex (FEN) figuram entre os estimulantes do sistema nervoso central (SNC) mais utilizados por condutores no trânsito brasileiro. O metilfenidato (MPH) é um fármaco que apresenta propriedades similares à cocaína e à anfetamina (AMP). Sua utilização como droga de rua e r...

  8. Servidor web empotrado en un FPGA para configurar un Controlador Maestro del Sistema Inteligente de Tráfico Cubano

    OpenAIRE

    Ríos Pérez, Frank Emilio; Polanco Carrillo, Franky; Moreno Vega, Valery

    2017-01-01

    RESUMEN En este artículo se presenta la implementación de un servidor web para configurar el Controlador Maestro del Sistema Inteligente de Tráfico desarrollado en Cuba. La programación del servidor se realizó en lenguaje C, para ejecutarse sobre un sistema operativo Linux empotrado en un FPGA. Se logró un mecanismo de configuración sencillo, de bajos recursos de cómputo, rápido y flexible.

  9. How to stir a revolution as a reluctant rebel: Rudolf Trümpy in the Alps

    Science.gov (United States)

    Şengör, A. M. Celâl; Bernoulli, Daniel

    2011-07-01

    Rudolf Trümpy (1921-2009) was one of the great Alpine geologists of the twentieth century and an influential figure in the international geological community. He played a dominant role in the change of opinion concerning the Alpine evolution by showing that normal faulting dominated the early development of the Alpine realm from the Triassic to the early Cretaceous. This provided a convenient model for later plate-tectonic interpretations of collisional mountain belts. His further recognition of strike-slip faulting during all stages of the Alpine evolution presaged the realisation that the Alps were not built by a simple open-and-shut mechanism. Trümpy was educated during an intellectual lull, a time when simplistic models of the earth behaviour inherited from the middle of the nineteenth century became prevalent under the influence of a close-minded, positivist approach to geological problems. This period, which we term the Dark Intermezzo, lasted from about 1925 to 1965. The grand syntheses of Suess and Argand which preceded this period were viewed from this narrow angle and consequently misunderstood. It was thought that earth history was punctuated by global orogenic events of short duration taking place within and among continents and oceans whose relative positions had remained fixed since the origin of the planet. These views, summarised under the term `fixism', were developed when the ocean floors were almost totally unknown. When data began coming in from the post World War II oceanographic surveys, the world geological community was slow to receive and digest them. Trümpy followed these developments closely, realising that his work was important in placing the geology of the mountain belts within the emerging, new theoretical framework. He adopted the position of a critic and emphasised where detailed knowledge of the Alps, unquestionably the best known mountain belt in the world, supported and where it contradicted the new ideas. His voice was

  10. Estudo comparativo dos constituintes químicos de Brosimum gaudichaudii Trécul e do medicamento V

    OpenAIRE

    Lourenço, Miriam Verginia [UNESP

    2001-01-01

    Brosimum gaudichaudii Trécul é uma planta medicinal utilizada na medicina tradicional no tratamento de doenças de pele, assim como o vitiligo. As furanocumarinas lineares psoraleno e bergapteno são os principais compostos responsáveis por esse efeito. O medicamento “V” produzido a partir do vegetal Brosimum gaudichaudii é usado pela população no tratamento do vitiligo, por ser alegado que o mesmo contém bergapteno. Entretanto, nada é conhecido a respeito do conteúdo de bergapteno nesse medica...

  11. An Automatic Framework Using Space-Time Processing and TR-MUSIC for Subsurface and Through-Wall Multitarget Imaging

    Directory of Open Access Journals (Sweden)

    Si-hao Tan

    2012-01-01

    Full Text Available We present an automatic framework combined space-time signal processing with Time Reversal electromagnetic (EM inversion for subsurface and through-wall multitarget imaging using electromagnetic waves. This framework is composed of a frequency-wavenumber (FK filter to suppress direct wave and medium bounce, a FK migration algorithm to automatically estimate the number of targets and identify target regions, which can be used to reduce the computational complexity of the following imaging algorithm, and a EM inversion algorithm using Time Reversal Multiple Signal Classification (TR-MUSIC to reconstruct hidden objects. The feasibility of the framework is demonstrated with simulated data generated by GPRMAX.

  12. Investigation of P(VDF-TrFE)/ZrO{sub 2}-MMA polymer composites applied to radiation shielding

    Energy Technology Data Exchange (ETDEWEB)

    Fontainha, C.C.P. [Depto. de Engenharia Nuclear - UFMG, Av. Antonio Carlos 6627, 31270-970 Belo Horizonte, MG (Brazil); Baptista Neto, A.T.; Santos, A.P.; Faria, L.O. [Centro de Desenvolvimento da Tecnologia Nuclear, Av. Antonio Carlos 6627, C.P. 941, 30270-901, Belo Horizonte, MG (Brazil)

    2015-07-01

    Exposure to high radiation dose in medical diagnostic imaging procedures can lead patients to suffer tissue damaging. However, there are several studies that identify significant dose reduction with the use of radiation protective attenuators, minimizing the delivered dose in the region that covers the main beam, while preserving the diagnostic quality of the generated image. Most radiation attenuator materials are produced from shielding metal containing composites, whose efficiency is the goal of investigations around the world. In this context, polymeric materials were chosen for this investigation in order to provide light-weighted and flexible protective composites, a must in personal protective shielding. Therefore, this work is concerned to the investigation of poly(vinylidene fluoride - try-fluor-ethylene) [P(VDF-TrFE)] copolymers mixed with zirconia nanoparticles. The resulting polymer composites, prepared with 1, 2, 3, 5 and 10 at.% of ZrO{sub 2} nanoparticles, were investigated for application as protective shielding in some interventional radiology procedures. Two variety of composites were produced, one using pure ZrO{sub 2} nanoparticles and the other using sol-gel route with zirconium butoxide as the precursor for zirconium oxide nano-clusters. The P(VDFTrFE)/ ZrO2-MMA polymer composites produced by sol-gel route have provided a much better dispersion of the pure ZrO{sub 2} material into the P(VDF-TrFE) host matrix. UV-Vis and FTIR spectrometry and differential scanning calorimetry (DSC) were used to characterize the composite samples. FTIR data reveal a possible link between the MMA monomers with the P(VDF-TrFE) chain through shared C=O bonds. The radiation shielding characterization was conducted by using a 70 kV x-rays beam which is applicable, for instances, in catheter angiography. The results demonstrate that composites with 10% of ZrO{sub 2}, and only 1.0 mm thick, can attenuate 60% of the x-rays beam. The composite density was evaluated to be

  13. Process Optimization of P(VDF-TrFE)-BaTiO3 Nanocomposites for Storage Capacitor Applications

    KAUST Repository

    Almadhoun, Mahmoud N.

    2011-07-11

    Increasing demands for efficient energy storage in microelectronics has pushed the scientific community towards finding suitable materials that can effectively deliver high pulse power in miniaturized systems. Polymer-ceramic composites are considered to be one possible solution towards the fabrication of high energy density capacitors, whether as embedded capacitors or gate insulators in organic field effect transistors (OFETs). Selecting high permittivity ceramics mixed with polymers with high breakdown field strengths would be the wisest approach towards enhancing energy storage. As such, novel ferroelectric polymers such as P(VDF-TrFE-CTFE) are being developed and researched, all displaying record dielectric values (K > 50) as promising candidates for high energy density composite capacitors (> 25 J/cm3). However, much work is still needed to understand the interaction mechanisms between the phases. We aim to seek an understanding of the processing challenges, especially in terms of fabricating thin film ferroelectric polymers and their application in nanocomposite capacitors while effectively maintaining optimized performance when embedded in flexible electronics. A process for synthesizing high performance P(VDF-TrFE) thin films is developed realizing the importance of controlling several process parameters to achieve high quality devices. Electrical and physicochemical characterization demonstrate how the performance of the polymer films improves with prolonged annealing periods by allowing sufficient time for solvent evaporation, crystallization and preferential-orientation of the crystallites. The polymer P(VDF-TrFE) is then used as a host material with barium titanate (BTO) nanoparticles below 100 nm (K = 150) as a ceramic filler in nanocomposite films. Facile surface modification by hydroxylation proved to be essential in the performance of the devices in terms of leakage current. A decrease of approximately 2 orders of magnitude in current leakage is

  14. SU-F-I-58: Image Quality Comparisons of Different Motion Magnitudes and TR Values in MR-PET

    Energy Technology Data Exchange (ETDEWEB)

    Patrick, J; Thompson, R [Lawson Health Research Institute, London, Ontario (Canada); Tavallaei, M; Drangova, M [Robarts Research Institute, London, Canada, London, Ontario (Canada); Stodilka, R [Western University, Canada, London, Ontario (Canada); Gaede, S [London Regional Cancer Program, London, Ontario (Canada)

    2016-06-15

    Purpose: The aim of this work is to evaluate the accuracy and sensitivity of a respiratory-triggered MR-PET protocol in detecting four different sized lesions at two different magnitudes of motion, with two different TR values, using a novel PET-MR-CT compatible respiratory motion phantom. Methods: The eight-compartment torso phantom was setup adjacent to the motion stage, which moved four spherical compartments (28, 22, 17, 10 mm diameter) in two separate (1 and 2 cm) linear motion profiles, simulating a 3.5 second respiratory cycle. Scans were acquired on a 3T MR-PET system (Biograph mMR; Siemens Medical Solutions, Germany). MR measurements were taken with: 1) Respiratory-triggered T2-weighted turbo spin echo (BLADE) sequence in coronal orientation, and 2) Real-time balanced steady-state gradient echo sequence (TrueFISP) in coronal and sagittal planes. PET was acquired simultaneously with MR. Sphere geometries and motion profiles were measured and compared with ground truths for T2 BLADE-TSE acquisitions and real time TrueFISP images. PET quantification and geometry measurements were taken using standardized uptake values, voxel intensity plots and were compared with known values, and examined alongside MR-based attenuation maps. Contrast and signal-to-noise ratios were also compared for each of the acquisitions as functions of motion range and TR. Results: Comparison of lesion diameters indicate the respiratory triggered T2 BLADE-TSE was able to maintain geometry within −2 mm for 1 cm motion for both TR values, and within −3.1 mm for TR = 2000 ms at 2 cm motion. Sphere measurements in respiratory triggered PET images were accurate within +/− 5 mm for both ranges of motion for 28, 22, and 17 mm diameter spheres. Conclusion: Hybrid MR-PET systems show promise in imaging lung cancer in non-compliant patients, with their ability to acquire both modalities simultaneously. However, MR-based attenuation maps are still susceptible to motion derived artifacts and

  15. A luta contra o Tordesilhas Nuclear : três momentos da política nuclear brasileira (1969- 1998)

    OpenAIRE

    Bandarra, Leonardo Carvalho Leite Azevedo

    2017-01-01

    A presente dissertação avalia como o Brasil adaptou sua política nuclear ao regime internacional de não proliferação nuclear e destaca qual o papel das relações bilaterais do Brasil nesse processo. Argumenta-se que a adesão brasileira ao regime internacional de não proliferação nuclear adveio tanto do interesse brasileiro em obter tecnologia do Norte Global quanto da aproximação com a Argentina. Para desenvolver a narrativa histórica, definiram-se três momentos do processo referido processo d...

  16. Calibration of BAS-TR image plate response to high energy (3-300 MeV) carbon ions

    Science.gov (United States)

    Doria, D.; Kar, S.; Ahmed, H.; Alejo, A.; Fernandez, J.; Cerchez, M.; Gray, R. J.; Hanton, F.; MacLellan, D. A.; McKenna, P.; Najmudin, Z.; Neely, D.; Romagnani, L.; Ruiz, J. A.; Sarri, G.; Scullion, C.; Streeter, M.; Swantusch, M.; Willi, O.; Zepf, M.; Borghesi, M.

    2015-12-01

    The paper presents the calibration of Fuji BAS-TR image plate (IP) response to high energy carbon ions of different charge states by employing an intense laser-driven ion source, which allowed access to carbon energies up to 270 MeV. The calibration method consists of employing a Thomson parabola spectrometer to separate and spectrally resolve different ion species, and a slotted CR-39 solid state detector overlayed onto an image plate for an absolute calibration of the IP signal. An empirical response function was obtained which can be reasonably extrapolated to higher ion energies. The experimental data also show that the IP response is independent of ion charge states.

  17. T-R Cycle Characterization and Imaging: Advanced Diagnostic Methodology for Petroleum Reservoir and Trap Detection and Delineation

    Energy Technology Data Exchange (ETDEWEB)

    Ernest A. Mancini; William C. Parcell; Bruce S. Hart

    2005-09-19

    The principal research effort for Year 2 of the project is on stratigraphic model assessment and development. The research focus for the first six (6) months of Year 2 is on T-R cycle model development. The emphasis for the remainder of the year is on assessing the depositional model and developing and testing a sequence stratigraphy model. The development and testing of the sequence stratigraphy model has been accomplished through integrated outcrop, well log and seismic studies of Mesozoic strata in the Gulf of Mexico, North Atlantic and Rocky Mountain areas.

  18. Tránsito del Derecho Penal Internacional desde el Tratado de Versalles y de Nuremberg hasta Roma

    OpenAIRE

    Castaño, Deissy Motta

    2012-01-01

    El marco del presente artículo se sustenta en la trascendencia del análisis de las instituciones internacionales en relación con los delitos contemplados como crímenes de guerra en conflagraciones entre Estados y su intervención en la problemática de la violencia interna. El tránsito del derecho penal internacional desde el Tratado de Versalles y de Nuremberg hasta Roma, constituye una aproximación a una genealogía histórica del derecho internacional, relativo a los crímenes de guerra durante...

  19. Síndrome de Klippel-Trenaunay-Parkes-Weber com angiomatose medular Klippel-Trénaunay-Parkes-Weber syndrome with spinal cord angioma: a case report

    Directory of Open Access Journals (Sweden)

    James Pitagoras de Mattos

    1975-09-01

    Full Text Available É relatado um caso de síndrome de Klippel-Trénaunay-Parkes-Weber associada a angiomatose medular. O autor salienta ter encontrado na literatura somente uma referência com tal associação.A case of Klippel-Trénaunay-Parkes-Weber syndrome associated with spinal cord angioma is reported. The author points out that it was found only one reference in literature with such association.

  20. Čezmejno sodelovanje na primeru občine Tržič = The crossborder cooperation: a case study of the Tržič municipality

    Directory of Open Access Journals (Sweden)

    Irena Mrak

    1998-01-01

    Full Text Available The Municipality of Tržič borders with the Republic of Austria at the main ridge of the Karavanke mountain. Cooperation with the neighbouring communities Borovlje/Ferlach and Sele/Zell Pfare started in the eighties and it has become more intense after the year 1991. The border that was once separating the inhabitants on both sides of the mountain ridge has become more opened after the slovenian independence but the border control is after Schengen agreement more severe. Remote mountain border areas where access used to be limited were suddenly recognised as a great touristic potential. In the recent years the Municipality of Tržič together with Austrian partners managed to form some joined agriculture and tourism development projects within the PHARE programme (CBC - Crossborder Cooperation and ECOS - Ouverture. The projects deal with the regrowing of buckwheat, preservation of a special sheep breed - jezersko solčavska sheep, activation of the natural monument Dovžan gorge which will be logistically connected to Tscheppa gorge on the austrian side. Within the ECOS Ouverture programme the project of Thematic trails around the Košuta mountain has been initiated in order to reactivate and connect hidden natural and cultural potentials into integrated touristic offer of this part of the Karavanke mountain.

  1. Diferentes como só nós. O associativismo GLBT português em três andamentos

    Directory of Open Access Journals (Sweden)

    António Fernando Cascais

    2012-10-01

    Full Text Available O presente texto toma como eixo de análise o modo como a diferença específica da formação social portuguesa determina e se exprime na sociogénese do associativismo GLBT nas três últimas décadas. É possível traçar uma periodização dele em três estádios, à qual deve atribuir‑se sobretudo um valor heurístico: o primeiro de 1974 até 1991, que pode dividir‑se em duas fases, uma anterior e outra posterior ao surgimento da epidemia de Sida no nosso país; o segundo, entre 1990-1991 e 1995-1997; e o terceiro, de 1997 até ao presente. A produção de conhecimento sobre o associativismo GLBT tem ainda de se articular com duas outras pesquisas: sobre os seus detractores e inimigos, antigos e neófitos, e sobre a comunidade que o associativismo representa ou de que emerge, com uma história, uma identidade e uma cultura que explicam as razões da adesão ou da resistência a ele.

  2. Transformative piezoelectric enhancement of P(VDF-TrFE) synergistically driven by nanoscale dimensional reduction and thermal treatment.

    Science.gov (United States)

    Ico, G; Myung, A; Kim, B S; Myung, N V; Nam, J

    2018-02-08

    Despite the significant potential of organic piezoelectric materials in the electro-mechanical or mechano-electrical applications that require light and flexible material properties, the intrinsically low piezoelectric performance as compared to traditional inorganic materials has limited their full utilization. In this study, we demonstrate that dimensional reduction of poly(vinylidene fluoride trifluoroethylene) (P(VDF-TrFE)) at the nanoscale by electrospinning, combined with an appropriate thermal treatment, induces a transformative enhancement in piezoelectric performance. Specifically, the piezoelectric coefficient (d 33 ) reached up to -108 pm V -1 , approaching that of inorganic counterparts. Electrospun mats composed of thermo-treated 30 nm nanofibers with a thickness of 15 μm produced a consistent peak-to-peak voltage of 38.5 V and a power output of 74.1 μW at a strain of 0.26% while sustaining energy production over 10k repeated actuations. The exceptional piezoelectric performance was realized by the enhancement of piezoelectric dipole alignment and the materialization of flexoelectricity, both from the synergistic effects of dimensional reduction and thermal treatment. Our findings suggest that dimensionally controlled and thermally treated electrospun P(VDF-TrFE) nanofibers provide an opportunity to exploit their flexibility and durability for mechanically challenging applications while matching the piezoelectric performance of brittle, inorganic piezoelectric materials.

  3. O problema da oralidade em Três Traduções de Of Mice and Men, de John Steinbeck

    Directory of Open Access Journals (Sweden)

    Johnwill Costa Faria

    2012-07-01

    Full Text Available http://dx.doi.org/10.5007/2175-7968.2012v1n29p53   No traduzir, uma grande questão envolve a diversidade linguística, quando um escritor resolve dar uma voz mais popular aos personagens de um romance literário, na forma de um dialeto sem prestígio, estigmatizado. Um desses escritores, John Steinbeck, em Of mice and men, apresenta seus personagens com um falar bem típico, que foge ao inglês padrão. Assim, este artigo discute problemas de traduzir a oralidade presente nesse romance, pelo exemplo de três traduções em português, em três épocas distintas: Érico Veríssimo (1940, Myriam Campello (1991 e Ana Ban (2005. Deste modo, observa-se como e por que esses tradutores propõem soluções diferentes para a linguagem dos diálogos.

  4. Involucramiento del Padre en la Crianza: Una Mirada Tríadica de las Relaciones Familiares Tempranas

    Directory of Open Access Journals (Sweden)

    Francisca Pérez Cortés

    2014-11-01

    Full Text Available Considerando los beneficios de una paternidad activa en el desarrollo de niños y niñas, así como en las dinámicas familiares en general, los profesionales del área de la salud deben ser agentes activos en la promoción de la participación de madres y padres en la crianza. El siguiente artículo busca introducir en el contexto nacional una herramienta que amplía la mirada del desarrollo infantil y las relaciones al interior de la familia, desde la díada a la tríada. El Lausanne Trilogue Play (LTP es una herramienta observacional, desarrollada por Fivaz-Depeursinge, Frascarolo y Corboz-Warnery (1996 que permite la evaluación estandarizada de la “alianza familiar”, corroborando la importancia de incorporar al padre en los estudios de procesos e interacciones familiares, así como la existencia de un efecto familiar tríadico desde etapas tempranas.

  5. Examining sex differences in DSM-IV-TR narcissistic personality disorder symptom expression using Item Response Theory (IRT).

    Science.gov (United States)

    Hoertel, Nicolas; Peyre, Hugo; Lavaud, Pierre; Blanco, Carlos; Guerin-Langlois, Christophe; René, Margaux; Schuster, Jean-Pierre; Lemogne, Cédric; Delorme, Richard; Limosin, Frédéric

    2017-12-14

    The limited published literature on the subject suggests that there may be differences in how females and males experience narcissistic personality disorder (NPD) symptoms. The aim of this study was to use methods based on item response theory to examine whether, when equating for levels of NPD symptom severity, there are sex differences in the likelihood of reporting DSM-IV-TR NPD symptoms. We conducted these analyses using a large, nationally representative sample from the USA (n=34,653), the second wave of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). There were statistically and clinically significant sex differences for 2 out of the 9 DSM-IV-TR NPD symptoms. We found that males were more likely to endorse the item 'lack of empathy' at lower levels of narcissistic personality disorder severity than females. The item 'being envious' was a better indicator of NPD severity in males than in females. There were no clinically significant sex differences on the remaining NPD symptoms. Overall, our findings indicate substantial sex differences in narcissistic personality disorder symptom expression. Although our results may reflect sex-bias in diagnostic criteria, they are consistent with recent views suggesting that narcissistic personality disorder may be underpinned by shared and sex-specific mechanisms. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Comparative analysis of LytS/LytTR-type histidine kinase/response regulator systems in γ-proteobacteria.

    Directory of Open Access Journals (Sweden)

    Stefan Behr

    Full Text Available Bacterial histidine kinase/response regulator systems operate at the interface between environmental cues and physiological states. Escherichia coli contains two LytS/LytTR-type histidine kinase/response regulator systems, BtsS/BtsR (formerly YehU/YehT and YpdA/YpdB, which have been identified as pyruvate-responsive two-component systems. Since they exhibit remarkable similarity, we analyzed their phylogenetic distribution within the γ-proteobacteria, and experimentally characterized them in a set of representative species. We found that BtsS/BtsR is the predominant LytS/LytTR-type two-component system among γ-proteobacteria, whereas YpdA/YpdB primarily appears in a supplementary role. Based on our observations in E. coli, we used the highly conserved DNA-binding motifs to test the in vivo functionality of both systems in various genera, including Salmonella, Enterobacter, Citrobacter, Xenorhabdus, Yersinia, Aeromonas and Vibrio. The results suggest that, in all cases tested, BtsS/BtsR and YpdA/YpdB respond to different levels of pyruvate in the environment.

  7. Salud mental de migrantes centroamericanos indocumentados en tránsito por la frontera sur de México

    Directory of Open Access Journals (Sweden)

    César Infante-Xibille

    2015-05-01

    Full Text Available Objetivo. Conocer las necesidades percibidas de salud mental de migrantes centroamericanos indocumentados en tránsito por la ciudad de Tapachula, Chiapas. Material  y métodos. Estudio cualitativo realizado en Casa de Migrantes de Tapachula, Chiapas. Se realizaron 20 entrevistas semiestructuradas a diez mujeres y diez hombres migrantes. Se exploró el estado de salud mental y las expectativas de atención. Se retomaron nociones teórico-metodológicas de la fenomenología sociológica. Resultados. Los migrantes presentaban signos y síntomas de daños en su salud mental relacionados con experiencias vividas en el lugar de origen y en el tránsito por México. La percepción sobre su salud mental es influida por el modelo biomédico hegemónico. Las expectativas de servicios se relacionaron con la satisfacción de necesidades básicas. Conclusiones. Es necesario fortalecer la respuesta del sistema de atención en salud mental a partir de estrategias de cooperación y emprender acciones que promuevan la superación de una construcción biomédica de salud mental que estigmatiza, medicaliza, segrega y dificulta el acceso a servicios.

  8. P(VDF-TrFE)/ZrO{sub 2} polymer-composites for X-ray shielding

    Energy Technology Data Exchange (ETDEWEB)

    Fontainha, Crissia Carem Paiva [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Dept. de Engenharia Nuclear; Baptista Neto, Annibal Theotonio; Santos, Adelina Pinheiro; Faria, Luiz Oliveira de, E-mail: farialo@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2016-03-15

    Poly(vinylidene fluoride - tryfluorethylene) [P(VDF-TrFE)] copolymers were mixed with zirconia nanoparticles. The investigation was conducted with the intention to produce nanocompounds with potential to be used as protective patient shielding in radiological procedures. Polymer based nanocomposites with 1, 2, 3, 5 and 10 wt% of ZrO{sub 2} nanoparticles were prepared using sol-gel route with zirconium butoxide as the precursor for zirconium oxide nanoclusters. UV-Vis and FTIR spectrometry and differential scanning calorimetry (DSC) were used to characterize the composite samples. We observed a more homogeneous distribution of ZrO{sub 2} nanoparticles encapsulated by methyl methacrylate (MMA) into the polymeric matrix, when compared to composites made without the use of surface modifiers from methacrylate group. Apparently, this property is related to the absence of the strong MMA absorption band at 1745 cm{sup -1}, attributed to C=O bond, in the P(VDF-TrFE)/ZrO{sub 2} -MMA nanocomposites. The radiation damage due to high dose exposure was performed for gamma doses ranging from 100 kGy to 1,000 kGy. The radiation shielding characterization conducted using x-rays with effective energy of 40 keV has demonstrated that composites with 10% of ZrO{sub 2}, and only 1.0 mm thick, can attenuate 60% of the x-rays beam. (author)

  9. Trama trófica de una comunidad de peces en una pradera marina en el Caribe Venezolano

    Directory of Open Access Journals (Sweden)

    Adriana López-Ordaz

    2009-12-01

    Full Text Available Las praderas marinas son consideradas sitios importantes de alimentación para una variedad de especies de peces, por lo que en estos sistemas son frecuentes las interacciones tróficas complejas. En el presente trabajo se describió la trama trófica de la ictiofauna en una pradera marina ubicada en el Caribe Venezolano. Adicionalmente, se propuso una medida de la intensidad de consumo de cada presa (IC, considerando dos variables: la abundancia y la frecuencia de uso. Se realizaron ocho muestreos (en 4 horarios: 6:00, 12:00, 18:00 y 24:00 horas en agosto 2005 y enero 2006. Se capturaron 51 especies pertenecientes a 29 familias siendo Haemulidae la más abundante y se identificaron 28 items alimenticios dentro de los cuales, Crustácea fue el más importante como recurso alimenticio. La importancia de los gremios tróficos considerando la abundancia y la riqueza taxonómica de especies fue: bentófago>herbívoro>piscívoro. Las características de la trama trófica fueron las siguientes: 1 una mayor proporción de cadenas cortas (dos eslabones, 2 un elevado número de especies intermedias. 3 un elevado consumo de bentos, 4 unas bajas intensidades de consumo y 5 un reducido número de especies involucradas en el mayor número de uniones tróficas estimadas. Se obtuvieron diferencias temporales (horarias y mensuales en el número de especies (totales, intermedias y topes, de uniones totales, en la conectividad y en la longitud máxima de cadena. No se observó una variación temporal en la conectancia y sus valores resultaron parecidos a los reportados para otros ambientes marinos con distinta riqueza de especies. Por el contrario, los valores de conectividad resultaron menores a los obtenidos en ambientes con menor riqueza de especies. Como en otros reportes, los parámetros tróficos estimados fueron poco sensibles a los cambios intracomunitarios. IC resultó bajo, a excepción de lo obtenido para los copépodos harpacticoides y las larvas de

  10. Características psicométricas e dados normativos do Teste das Três Palavras e Três Figuras (3P3F no Brasil

    Directory of Open Access Journals (Sweden)

    Moura, Samara Melo

    2008-01-01

    Full Text Available O Teste das Três Palavras e Três Figuras (3P3F é um instrumento de avaliação rápida e multidimensional da memória episódica, desenvolvido para idosos. Ele ocuparia posição intermediária entre o item de memória do Mini Exame do Estado Mental (MEEM e tarefas mais complexas de listas de figuras e palavras. As características psicométricas de uma adaptação brasileira do 3P3F para amostras de 33 portadores de doença de Alzheimer (DA e 99 idosos cognitivamente normais demograficamente pareados foram investigadas. Adicionalmente, normas de desempenho foram desenvolvidas em um grupo de 350 idosos saudáveis. Os resultados revelam alta confiabilidade (a = 0,89 e poder descriminativo para a identificação das desordens cognitivas associadas à DA (ASC = 0,98; sensibilidade/especificidade = 94,9/92,3%. Observou-se a correlação do 3P3f com o MEEM e a Bateria de Avaliação Frontal (r = 0,65 e r = 0,46; p <0,05. Um modelo de regressão logística sugere a influência da idade e da escolaridade sobre os escores dos testes (B = 0,06 e B = 0,13; P <0,05. Os resultados sugerem adequação psicométrica do instrumento

  11. Mortes no trânsito do Rio de Janeiro, Brasil Traffic deaths in Rio de Janeiro, Brazil

    Directory of Open Access Journals (Sweden)

    Carlos Henrique Klein

    1994-01-01

    Full Text Available A evolução urbana do município do Rio de Janeiro durante o século XX, especialmente a partir da sua segunda metade, é fortemente marcada por crescentes privilégios concedidos ao crescimento da utilização dos meios de transporte de massa e, principalmente, individuais, feitos por veículos a motor de explosão. Uma das conseqüências desta política é a ascenção da mortalidade por acidentes de trânsito, verificada durante a década de 80, entre homens e mulheres de todas as idades. Neste trabalho demonstra-se também que, em 1990, apenas cerca de 1/3 das vítimas fatais nos acidentes de trânsito estavam "embarcadas" nos veículos. Portanto, a maioria dos óbitos por este tipo de acidente, cerca de 2/3, ocorreu por atropelamentos. Isto indica a necessidade de o poder público reverter a prioridade na prevenção das mortes por acidentes de trânsito em favor de medidas eficazes que protejam os pedestres.The evolution of the city of Rio de Janeiro during the 20th century, particularly since 1950, has been strongly characterized by increasing concession of privileges for the use of motor vehicles for both mass (and especially individual transportation. One of the main consequences of this policy was a rising mortality rate due to traffic accidents during the 1980s, among men and women of all ages. This paper demonstrates that in 1990 only about one-third of the fatal victims of traffic accidents were inside the vehicles involved. In Rio de Janeiro, the majority of deaths from this kind of accident (approximately two-thirds were pedestrians. Thus, policies aimed at reducing traffic-related mortality should give priority to the protection of pedestrians rather than drivers.

  12. Território, sistema de justiça criminal e aprisionamento na tríplice fronteira

    OpenAIRE

    Ziemann, Marcos Afonso Lopes; Zomighani Junior, James Humberto

    2016-01-01

    Anais do V Encontro de Iniciação Científica e I Encontro Anual de Iniciação ao Desenvolvimento Tecnológico e Inovação – EICTI 2016 - 05 e 07 de outubro de 2016 – Sessão Ciências Humanas O intuito desta pesquisa é conhecer e compreender as complexidades existentes entre os elementos do espaço (os homens, as firmas, as instituições, o chamado meio ecológico e as infraestruturas) e suas relações dentro dos complexos carcerários existentes aqui na tríplice fronteira entre Brasil, Arg...

  13. Identidades en tránsito urbano: prácticas corporales en desplazados hacia Medellín

    Directory of Open Access Journals (Sweden)

    Rubiela Arboleda Gómez

    2013-01-01

    Full Text Available En este artículo se presentan hallazgos de la investigación “Improntas política-motricidad y su mediación en la relación cuerpo-ciudad de los desplazados hacia la ciudad de Medellín”, realizado entre el 2010 y el 2012. Se propone identificar prácticas emergentes relativas a la dimensión política en nexo con la motricidad, que favorecen la reconfiguración identitaria en el tránsito rural-urbano, producto del destierro y en el marco del conflicto armado en Colombia. Se concluye con el papel de la política vinculada al cuerpo en el proceso de adaptación de los sujetos desterrados en la ciudad.

  14. El hipotexto figurativo en “Vista del amanecer en el trópico” de Guillermo Cabrera Infante

    Directory of Open Access Journals (Sweden)

    Alessandra Ghezzani

    2015-07-01

    Full Text Available Vista del amanecer en el trópico narrates Cuban history through its most important steps. The book is composed by 101 fragments or “viñetas”; some of them are descriptions of images (lithographies, drawings, paintings, photographs related to characters or events of that history. This article presents the results of a research aimed at identifying those “absent images” (a subject that critics have up to now ignored, discovering the sources exploited by the author Cabrera Infante, highlighting the discourse strategies underlying their verbal representation and, finally, assessing how the image selection and their representation contribute to shape the vision of cuban history that comes to light from the book.

  15. Carbon Molecular Sieve Membranes Derived from Tröger's Base-Based Microporous Polyimide for Gas Separation.

    Science.gov (United States)

    Wang, Zhenggong; Ren, Huiting; Zhang, Shenxiang; Zhang, Feng; Jin, Jian

    2018-03-09

    Carbon molecular sieve (CMS)-based membranes have attracted great attention because of their outstanding gas-separation performance. The polymer precursor is a key point for the preparation of high-performance CMS membranes. In this work, a microporous polyimide precursor containing a Tröger's base unit was used for the first time to prepare CMS membranes. By optimizing the pyrolysis procedure and the soaking temperature, three TB-CMS membranes were obtained. Gas-permeation tests revealed that the comprehensive gas-separation performance of the TB-CMS membranes was greatly enhanced relative to that of most state-of-the-art CMS membranes derived from polyimides reported so far. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Penfigoide bolhoso no adulto mais jovem: relato de três casos Bullous pemphigoid in younger adults: three case reports

    Directory of Open Access Journals (Sweden)

    Roberta Richter Zanella

    2011-04-01

    Full Text Available O penfigoide bolhoso é uma dermatose bolhosa autoimune subepidérmica, mais comumente observada na população idosa (acima dos 70 anos. Autoanticorpos são formados contra antígenos específicos da zona de membrana basal: BP180 e BP230 (proteínas do hemidesmossomo. Apresentamos três casos de penfigoide bolhoso, em adultos com menos de 50 anos de idade, destacan do as peculiaridades clínicas na faixa etária mais jovem.Bullous pemphigoid is an autoimmune subepidermal bullous dermatosis more commonly observed in the elderly (over 70 years old. Autoantibodies are produced for specific antigens of the epidermal basement membrane zone: BP 180 and BP 230 (hemidesmosome proteins. We report three cases of bullous pemphigoid in adults younger than 50 years old, discussing the clinical characteristics of the disease in younger patients.

  17. Aporia e passagem: a sobrevivência do "trágico" em Guimarães Rosa

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    Ettore Finazzi-Agrò

    2002-03-01

    Full Text Available O intuito deste texto é pôr em questão a persistência do “pensamento trágico” em Grande sertão: veredas, a partir de uma reflexão sobre o estatuto essencialmente (i.e., ontologicamente aporético da obra de João Guimarães Rosa. Romance da espera, de fato, ele se inclui por completo naquele lugar “terceiro”, suspenso entre esperança e desespero, que se delineia no interior de qualquer contradição e que constitui, desde sempre, o logos da tragédia.

  18. A história por trás da foto = The story behind the photo

    Directory of Open Access Journals (Sweden)

    Barros, Luiz Felipe Barros de

    2016-01-01

    Full Text Available Este artigo, intitulado “A história por trás da foto”, tem por objetivo resgatar uma passagem singular e esquecida da aviação comercial brasileira, especialmente nas décadas de 1930 e 1940. Utiliza-se o método monográfico e bibliográfico para, a partir da análise detalhada de uma fotografia sem qualquer relevância, descortinar e revelar a forte influência germânica na América do Sul. Mostra-se os reflexos da cultura germânica, principalmente no modal aéreo, bem como as particularidades das relações Brasil-Alemanha-Brasil após a Primeira Guerra Mundial

  19. Verification the 25-kgy dose using the iso standard iso/tr 13409 for the production of bone grafts

    International Nuclear Information System (INIS)

    Otero, I.; Barrera, L.; Diaz, A.; Napoles, D.; Sanchez, E

    2001-01-01

    The purpose of this work was to verify the 25 Gy dose using the ISO standard ISO/TR 13409 for the production of bone grafts from the Tissue Bank ORTOP of the Complejo Cientifico Ortopedico Internacional Frank Pais. We performed two principal microbiological activities: bioburden estimate, pre-sterilization count plus a compensation for the efficiency of the recovery method, by ISO 11737-1 and test of sterility by ISO 11737-2. The techniques for Bioburden estimation could be direct or indirect. Choice of direct vs. indirect depends on number of contaminating micro-organisms, product configuration, ability to remove microbial contamination, effect of removal method on microbial viability, types and location of micro-organisms, nature of product and culture conditions. For a test of sterility, he product unit or SIP putted direct immersion in educated culture medium and incubate. Keep precaution to minimize level to the false positives is necessary

  20. Mujeres subsaharianas posibles víctimas de trata. Derecho a la salud en tránsito

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    Nuria Cordero Ramos

    2016-07-01

    Full Text Available En este artículo se abordan los problemas de salud integral derivados de la violencia de género a la que se ven sometidas las mujeres subsaharianas próximas a redes de trata, que cruzan fronteras y que se encuentran en Andalucía (España demandando servicios de salud. Así mismo, se analizan las dificultades con las que se encuentran éstas para ejercer su derecho a la salud en Andalucía, como lugar de tránsito, y las barreras que presentan los profesionales, condicionando su capacidad de intervención. El objetivo es fomentar la sensibilización y capacitación de los profesionales para favorecer la proximidad de los servicios sanitarios públicos en Andalucía a este colectivo.

  1. Modelo de previsión del tráfico en Santander: Año 2020

    OpenAIRE

    Campollo Canduela, Alfonso

    2015-01-01

    El presente trabajo consiste en un análisis de la previsión de la demanda de tráfico en transporte privado de viajeros en la ciudad de Santander (Cantabria, España) para el año 2020, entre las 8 y las 9 de la mañana de un día laborable, a partir de los datos procedentes de una encuesta domiciliaria, realizada por el Grupo de Investigación de Sistemas de Transporte (GIST) de la Universidad de Cantabria para un estudio previo, y el modelo de ordenación que el Plan General de Ordenación Urbana v...

  2. TR-LIF LIFETIME MEASUREMENTS AND HFR+CPOL CALCULATIONS OF RADIATIVE PARAMETERS IN VANADIUM ATOM (V I)

    International Nuclear Information System (INIS)

    Wang, Q.; Jiang, L. Y.; Shang, X.; Tian, Y. S.; Dai, Z. W.; Quinet, P.; Palmeri, P.; Zhang, W.

    2014-01-01

    Radiative lifetimes of 79 levels belonging to the 3d 3 4s4p, 3d 4 4p, 3d 3 4s5p, 3d 4 5p, and 3d 3 4s4d configurations of V I with energy from 26,604.807 to 46,862.786 cm –1 have been measured using time-resolved laser-induced fluorescence (TR-LIF) spectroscopy in laser-produced plasma. The lifetime values reported in this paper are in the range of 3.3-494 ns, and the uncertainties of these measurements are within ±10%. A good agreement was obtained with previous data. HFR+CPOL calculations have been performed and used to combine the calculated branching fractions with the available experimental lifetimes to determine semi-empirical transition probabilities for 784 V I transitions

  3. The low-mass stellar population in the young cluster Tr 37. Disk evolution, accretion, and environment

    Science.gov (United States)

    Sicilia-Aguilar, Aurora; Kim, Jinyoung Serena; Sobolev, Andrej; Getman, Konstantin; Henning, Thomas; Fang, Min

    2013-11-01

    Aims: We present a study of accretion and protoplanetary disks around M-type stars in the 4 Myr-old cluster Tr 37. With a well-studied solar-type population, Tr 37 is a benchmark for disk evolution. Methods: We used low-resolution spectroscopy to identify and classify 141 members (78 new ones) and 64 probable members, mostly M-type stars. Hα emission provides information about accretion. Optical, 2MASS, Spitzer, and WISE data are used to trace the spectral energy distributions (SEDs) and search for disks. We construct radiative transfer models to explore the structures of full-disks, pre-transition, transition, and dust-depleted disks. Results: Including the new members and the known solar-type stars, we confirm that a substantial fraction (~2/5) of disks show signs of evolution, either as radial dust evolution (transition/pre-transition disks) or as a more global evolution (with low small-dust masses, dust settling, and weak/absent accretion signatures). Accretion is strongly dependent on the SED type. About half of the transition objects are consistent with no accretion, and dust-depleted disks have weak (or undetectable) accretion signatures, especially among M-type stars. Conclusions: The analysis of accretion and disk structure suggests a parallel evolution of dust and gas. We find several distinct classes of evolved disks, based on SED type and accretion status, pointing to different disk dispersal mechanisms and probably different evolutionary paths. Dust depletion and opening of inner holes appear to be independent processes: most transition disks are not dust-depleted, and most dust-depleted disks do not require inner holes. The differences in disk structure between M-type and solar-type stars in Tr 37 (4 Myr old) are not as remarkable as in the young, sparse, Coronet cluster (1-2 Myr old), suggesting that other factors, like the environment/interactions in each cluster, are likely to play an important role in the disk evolution and dispersal. Finally, we

  4. Três ensaios sobre os mercados de gasolina, etanol e açúcar no Brasil

    OpenAIRE

    Melo, André de Souza

    2012-01-01

    Este trabalho é divido em três ensaios sobre o mercado de gasolina, etanol e açúcar no Brasil. O primeiro ensaio tem como objetivo analisar como o preço da gasolina reage a choques de demanda, oferta e atividade econômica. Analisa-se também como o preço se comporta, diante de mudanças no imposto sobre a gasolina (CIDE) e a mistura obrigatória do etanol na gasolina. Esse estudo é motivado pela grande importância do mercado de gasolina do Brasil, que desde 2002 é determinado pelas forças de mer...

  5. Inmigración, emigración y tránsito migratorio en Chiapas: un bosquejo general

    Directory of Open Access Journals (Sweden)

    María Eugenia Anguiano Téllez

    2008-06-01

    Full Text Available Se explora la condición actual del estado de Chiapas como territorio de inmigración nacional y extranjera, como entidad expulsora de migrantes al resto del país y Estados Unidos, y como espacio y trayecto de tránsito migratorio de guatemaltecos y migrantes de otras nacionalidades. Para ello, se analiza información que proporcionan el Instituto Nacional de Geografía, Estadística e Informática, el Consejo Nacional de Población, el Instituto Nacional de Migración y dos encuestas de flujos migratorios en las que participa El Colegio de la Frontera Norte.

  6. O roubo de escravos no Rio de Janeiro e o tráfico interno paralelo: 1808-1850

    Directory of Open Access Journals (Sweden)

    Luiz Carlos Soares

    1989-07-01

    Full Text Available A documentação policial da Côrte na primeira metade do século passado evidencia a freqüência de um comércio ilícito de escravos roubados e revendidos para as províncias vizinhas. Delineia-se a par do tráfico internacional de contrabando, um comércio marginal a preços bem menores, controlados em sua maioria por ciganos e seus intermediários. Também envolvia capitães de mato ou quadrilhas muito bem organizadas. Era um meio de fornecer mão-de-obra mais barata a pequenos proprietários. Por vezes este comércio envolvia libertos em alforria condicional, evidenciando uma circulação clandestina de parentes escravos.

  7. Acidentes de trânsito: uma visão qualitativa no Município de Campinas, São Paulo, Brasil

    Directory of Open Access Journals (Sweden)

    Marcos S. Queiroz

    2002-10-01

    Full Text Available Este artigo focaliza, numa perspectiva interdisciplinar qualitativa, o problema de acidentes de trânsito no Município de Campinas. Ele começa analisando o processo de municipalização do transporte e trânsito no município, com base nas representações sociais de técnicos da Secretaria Municipal de Transporte. Alguns números são trazidos à tona para mostrar uma queda significativa de mortes no trânsito em Campinas nos últimos dez anos. Esses números demonstram que as políticas públicas implementadas nesse setor têm sido positivas em vários aspectos. Atenção especial é dada aos objetivos, estratégias e obstáculos encontrados pelo poder local no processo de municipalização do trânsito. O artigo conclui enfatizando que, além da municipalização, o Estado necessita implementar políticas públicas específicas consistentes, principalmente aquelas voltadas à revitalização do transporte coletivo e a programas de educação no trânsito, a fim de se poder avançar no controle do problema.

  8. Papel trófico del microbial loop en un lago de inundación en la Amazonia Central

    Directory of Open Access Journals (Sweden)

    Pedro Caraballo Gracia

    2012-01-01

    Full Text Available Con el propósito de evaluar la participación de las bacterias heterotróficas en el flujo de carbono en la cadena trófica de un lago de inundación amazónico, colectas mensuales de estos microorganismos fueron realizadas durante el año hidrológico de diciembre de 2007 hasta noviembre de 2008, en las regiones litoral, pelágica y de macrófitas acuáticas del lago Catalão, en la Amazonia Central brasilera. Las bacterias fueron multiplicadas in vitro, usando como sustrato el carbono orgánico disuelto (COD del lago en cada una de las regiones estudiadas, para posterior análisis de la abundancia de isotopos estables de carbono y nitrógeno. Estos datos fueron confrontados con los valores de COD de los cuatro periodos limnológicos del lago (seca, inundación, llena y bajada de aguas. En general se encontró que la fuente principal de carbono de las bacterias heterotróficas fue aquella de origen C4, que presentó un aporte mínimo de 75%, en la medida en que el δ13C de las bacterias presentó valor medio de -17,72‰ ± 2,25. Confrontando ese valor, con el δ13C del zooplancton en el mismo período (-33,04‰±3,81 se concluye que el aporte de las bacterias heterotróficas al flujo de carbono hacia niveles tróficos superiores en el lago estudiado es mínimo.

  9. Mental health and wellbeing in spouses of persons with dementia: the Nord-Trøndelag Health Study.

    Science.gov (United States)

    Ask, Helga; Langballe, Ellen Melbye; Holmen, Jostein; Selbæk, Geir; Saltvedt, Ingvild; Tambs, Kristian

    2014-05-01

    Caring for a spouse diagnosed with dementia can be a stressful situation and can put the caregiving partner at risk of loss of mental health and wellbeing. The main aim of this study was to investigate the relationship between dementia and spousal mental health in a population-based sample of married couples older than 55 years of age. The association was investigated for individuals living together with their demented partner, as well as for individuals whose demented partner was living in an institution. Data on dementia were collected from hospitals and nursing homes in the county of Nord-Trøndelag, Norway. These data were combined with data on spousal mental health, which were collected in a population-based health screening: the Nord-Trøndelag Health Study (HUNT). Of 6,951 participating couples (>55 years), 131 included one partner that had been diagnosed with dementia. Our results indicate that after adjustment for covariates, having a partner with dementia is associated with lower levels of life satisfaction and more symptoms of anxiety and depression than reported by spouses of elderly individuals without dementia. Spouses living together with a partner diagnosed with dementia experienced moderately lower levels of life satisfaction (0.35 standard deviation [SD]) and more symptoms of depression (0.38 SD) and anxiety (0.23 SD) than did their non-caregiving counterparts. Having a partner with dementia that resided in a nursing home was associated with clearly lower life satisfaction. Compared with non-caregivers, these spouses reported lower levels of life satisfaction (1.16 SD), and also more symptoms of depression (0.38 SD), and more symptoms of anxiety (0.42 SD). Having a partner with dementia is associated with loss of mental health and reduced life satisfaction. The risk of adverse mental health outcomes is greatest after the partner's nursing home admission.

  10. FTIR spectroscopy as an alternative tool for high gamma dose dosimetry using P(VDF-TrFE) fluorinated copolymers

    Energy Technology Data Exchange (ETDEWEB)

    Medeiros, Adriana S.; Liz, Otavio S., E-mail: asm@cdtn.b [Universidade Federal de Minas Gerais (DEN/UFMG), Belo Horizonte, MG (Brazil). Dept. de Engenharia Nuclear; Faria, Luiz O., E-mail: farialo@cdtn.b [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2011-07-01

    Poly(vinylidene fluoride) [PVDF] is a semicrystalline homopolymer and some of its fluorinated copolymer has demonstrated to have sensitiveness to high doses of ionizing radiation. We have recently proposed a semicrystalline fluorinated PVDF copolymer, the poly(vinylidene-trifluorethylene) [P(VDF-TrFE], as a candidate for measuring larger dose ranges. In fact, in these copolymers the optical absorption peak at 274 nm has been used to measure gamma doses ranging from 1.0 to 100.0 kGy and the melting latent heat, collected by differential scanning calorimetry (DSC), have been used to measure gamma doses from 1.0 to 1,000.0 kGy. In this paper, the infrared stretching vibration of radio-induced in-chain unsaturations (CH=CF) in P(VDF-TrFE) copolymers has been considered as an alternative tool for high dose dosimetric purposes. FTIR spectroscopic data revealed two optical absorption bands at 1754 cm{sup -1} and 1854 cm{sup -1} whose intensities are unambiguously related to gamma delivered doses ranging from 100.0 kGy to 1,000.0 kGy. Fading was evaluated one month after irradiation. The results indicate that the sample dose evaluation should be performed in the first two hours after being exposed to the radiation beam. The radio-induced formation of unsaturations was also investigated by ultraviolet and visible spectroscopy, which has confirmed the gradual increase of conjugated C=C bonds with the absorbed dose. Our results indicate that quantitative analysis of FTIR absorption bands is a useful tool to perform a product end-point dosimetry in radiation processing facilities that use high gamma dose irradiation. (author)

  11. Adsorção e lixiviação de tebuthiuron em três tipos de solo

    Directory of Open Access Journals (Sweden)

    M. Dornelas De Souza

    2001-12-01

    Full Text Available Estudou-se a adsorção do herbicida tebuthiuron em três solos de Ribeirão Preto (SP: Latossolo Vermelho distrófico (LVd, Latossolo Vermelho distroférrico (LVdf e Neossolo Quartzarênico (RQ. Ajustaram-se isotermas de adsorção por meio de quatro modelos: linear, Freundlich, Lambert e Langmuir, para duas profundidades: 0-10 cm e 10-20 cm. Nos três tipos de solo, o melhor ajuste foi obtido com o modelo de Freundlich, escolhido com base nos seguintes critérios estatísticos: quadrado do coeficiente de correlação entre valores observados e preditos (R², quadrado médio do erro (QME, dispersão de resíduos padronizados e gráficos de probabilidade normal. Os coeficientes de partição do herbicida calculados com base em todo o solo (Kd ou com base no seu teor de carbono orgânico (K OC ou de matéria orgânica (K OM variaram de 0,723 a 2,573; de 135,4 a 374,3 e de 78,4 a 218,3 L kg-1, respectivamente, tendo ocorrido correlação significativa entre os valores de Kd e teor de carbono orgânico dos solos e teor de argila. Efetuou-se um teste de lixiviação em colunas, no qual se observou movimento do herbicida até à profundidade de 60 cm no RQ, 20 cm no LVd e 10 cm no LVdf, verificando-se uma relação inversa entre a profundidade alcançada pelo produto e o valor de Kf de Freundlich utilizado como estimador de Kd.

  12. SU-E-T-310: Dosimetric Comparison of Tandem and Ovoid (TO) Vs. Tandem and Ring (TR) Applicators in High-Dose Rate (HDR) Brachytherapy (BT) for the Treatment of Locally-Advanced Cervical-Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Kuo, L; Viswanathan, A; Damato, A [Brigham and Women’s Hospital, Boston, MA (United States)

    2015-06-15

    Purpose: To investigate the dosimetric differences associated with the use of TO or TR applicators for cervical-cancer HDR BT. Methods: The records of all cervical-cancer patients treated with image-guided HDR BT in 2013 were reviewed. Image-based planning based on isodose line and DVH metrics inspections was performed following the GEC-ESTRO recommendations. CTV volume, CTV D90, and rectum, bladder and sigmoid D2cc were collected as % of the prescription dose (80Gy EQD2). Patients receiving both TO and TR were identified and plans were compared (paired analysis). A Student T-test was used to evaluate statistical significance (p ≤ 0.05). Results: Twenty-eight patients were identified (20 TR only, 4 TO only, 4 TO and TR), associated with 116 plans (109 TR, 7 TO). Overall metrics: CTV volume, 26.5±10.4 cm3 (TR) and 39.1±14.0 cm3 (TO, p < 0.01); CTV D90, 126±28% (TR) and 110±15% (TO, p = 0.15); rectum D2cc, 56±11% (TR) and 58±19% (TO, p = 0.91); bladder D2cc, 74±20% (TR) and 88±19% (TO, p = 0.09); sigmoid D2cc, 52±17% (TR) and 49±20% (TO, p = 0.63). The paired analysis results were: CTV volume, 37.3±11.9 cm3 (TR) and 51.0±23.1 cm3 (TO, p = 0.23); CTV D90, 111±12% (TR) and 101±17% (TO, p = 0.50); rectum D2cc, 56±12% (TR) and 53±16% (TO, p = 0.71); bladder D2cc, 73±14% (TR) and 90±20% (TO, p = 0.22); sigmoid D2cc, 59±10% (TR) and 59±22% (TO, p = 0.98). Conclusion: TR and TO were both used with good dosimetric results. TO were used for patients with larger CTV volumes than TR, although paired analysis suggest that tissue distortion and contouring bias may partially explain this Result. CTV D90 on average > 80 Gy EQD2 were achieved in both groups despite the different CTV volume. Higher bladder D2cc for TO than TR was observed.

  13. Insular artefacts from Viking-Age burials from mid-Norway. A review of contact between Trøndelag and Britain and Ireland

    Directory of Open Access Journals (Sweden)

    Aina Margrethe Heen-Pettersen

    2014-12-01

    Full Text Available This article presents a detailed overview of the Insular artefacts found in Viking-Age burials from the Trøndelag region of mid-Norway, most of which have not previously been published in English. The archaeological evidence indicates that contact between Trøndelag and the British Isles was well established at an early stage of the Viking Age. The main evidence for contact comes from the 9th century, when a number of significant patterns can be discerned. Some local concentrations of Insular goods show the continuing importance of some pre-Viking centres, while other areas suggest co-operation between several neighbouring families in order to equip and provision overseas expeditions. Later, the datable Insular artefacts indicate significant changes in the nature of contact. North Sea trading towards the end of the Viking Age appears to be affected by increasing centralisation of power in Trøndelag during the 10th century.

  14. O planejamento urbano e os acidentes de trânsito: um estudo sobre o Município de Toledo - PR

    OpenAIRE

    Ruschel, Andressa Carolina

    2017-01-01

    O artigo propõe identificar como o planejamento urbano influencia nos acidentes de trânsito no Município de Toledo - PR no período de 2011 a 2015, dentro do Perímetro Urbano, partindo da problematização criada pelo alto índice de acidentes de trânsito no município. A metodologia utilizada foi através de aspectos conceituais da análise espacial e do planejamento urbano; coleta de dados primários nos Boletins de Ocorrência de Acidentes de Trânsito, em seguida tabelados e analisados conforme fun...

  15. A violência no trânsito : um estudo de cado do PVT - Recife/PE 2000-2004

    OpenAIRE

    de Sá Gondim, Getúlio

    2004-01-01

    A violência no trânsito tem se constituído em uma séria problemática para todos, cuja solução deve ser tratada no âmbito das políticas públicas. Este Trabalho de Conclusão de Mestrado teve como objeto de análise a violência no trânsito na cidade do Recife, no período de 2000 a 2004. Definiu como objetivo analisar se o Projeto Vida no Trânsito contribuiu para reduzir os índices de acidentes, a multiinstitucionalidade e a ação educativa conscientizadora por meio dos arte-educadores. A metodolog...

  16. Įvairių trąšų įtaka ekologiškai auginamiems žieminiams rugiams

    OpenAIRE

    Stelmokas, Svajūnas

    2009-01-01

    Lietuvos žemės ūkio universiteto Agroekologijos centro ekologinės gamybos ūkyje 2007-2008 m. atlikus fosforo ir kalio trąšų įtakos ekologiškai auginamiems žieminiams rugiams tyrimus nustatyta, kad didžiausias žieminių rugių derlingumas gautas tręšiant P60 fosforitmilčių norma. Didinant normą žieminių rugių derlingumas mažėjo. Lyginant fosforitmilčių normas tarpusavyje bei su netręštais žieminiais rugiais, esminių grūdų derlingumo skirtumų nenustatyta. Tręšimas fosforitmilčiais neturėjo esminė...

  17. Augalų, auginamų žaliajai trąšai, agrobiologinis įvertinimas ir įtaka svogūnų derliui

    OpenAIRE

    Starkutė, Roma; Duchovskienė, Laisvūnė; Zalatorius, Zytautas

    2006-01-01

    2003–2005 m. Lietuvos sodininkystės daržininkystės institute ekologiškai daržovėms auginti skirtame bandymų lauke tirti ir įvertinti žaliajai trąšai tinkamiausi augalai ir nustatyta jų įtaka ekologiškai auginamų svogūnų derliui. Tirti augalai žaliajai trąšai: miežiai, miežiai su dobilų įsėliu, vasariniai kviečiai, žirnių ir avižų mišinys, aliejiniai ridikai. Kontrolinis variantas – juodasis pūdymas. Nustatyta, kad žaliajai trąšai auginamų augalų biomasė armenyje paliko nevienodą organinės med...

  18. Tráfego veicular e mortalidade por doenças do aparelho circulatório em homens adultos

    OpenAIRE

    Habermann, Mateus; Gouveia, Nelson

    2011-01-01

    OBJETIVO: Analisar a associação entre indicadores de exposição à poluição por tráfego veicular e mortalidade por doenças do aparelho circulatório em homens adultos. MÉTODOS: Foram analisadas informações sobre vias e volume de tráfego no ano de 2007 fornecidas pela companhia de engenharia de tráfego local. Mortalidade por doenças do aparelho circulatório no ano de 2005 entre homens > 40 anos foram obtidas do registro de mortalidade do Programa de Aprimoramento de Informações de Mortalidade do ...

  19. "Arrancale los dientes al trópico": ambiente,enfermedad y el programa sanitario de Estados Unidos en Panamá, 1904-1914

    Directory of Open Access Journals (Sweden)

    Paul Sutter

    2000-01-01

    Full Text Available Apoyado en fuentes escritas durante y después de la construcción del Canal de Panamá (1904- 1914, este artículo examina la forma en que los estadunidenses conceptualizaron los trópicos de Panamá y el modo en que dicha conceptualización orientó su política, en especial la sanitaria, durante el periodo de construcción del canal. Debido a que las enfermedades tropicales, en especial la malaria y la fiebre amarilla, ocupaban un lugar central en el modo de concebir los trópicos por parte de los estadunidenses, el objetivo de este trabajo es mostrar que los problemas de enfermedades en Panamá eran el resultado de complejas interacciones ambientales y sociales, y no una mera característica natural de los trópicos.

  20. La conducta social en el tráfico: Práctica y valoración de la población española.

    OpenAIRE

    Alonso Plá, Francisco Manuel; Sanmartín, Jaime; Esteban Martínez, Cristina; Calatayud Miñana, Constanza; Alamar Rocatí, Beatriz; López-de-Cózar, Elena; Pastor Soriano, Juan Carlos

    2007-01-01

    Si partimos de que el comportamiento de una persona se compone por el conjunto de sus conductas ¿Cómo podemos calificar a una persona como buena o como mala? Si nos centráramos en el ámbito del tráfico nos sentiríamos seguros al afirmar que existen “malas” conductas en el tráfico. Así podemos definir como conductas “malas” en el tráfico todas las conductas que ponen en peligro a algún otro usuario de la vía o a uno mismo. Con la misma rotundidad podemos afirmar que existen personas que ...

  1. SAG/ROC-SCFβ-TrCP E3 Ubiquitin Ligase Promotes Pro-Caspase-3 Degradation as a Mechanism of Apoptosis Protection

    Directory of Open Access Journals (Sweden)

    Mingjia Tan

    2006-12-01

    Full Text Available Skp1-cullin-F-box protein (SCF is a multicomponent E3 ubiquitin (Ub ligase that ubiquitinates a number of important biologic molecules such as p27, β-catenin, and lκB for proteasomal degradation, thus regulating cell proliferation and survival. One SCF component, SAG/ROC2/Rbx2/Hrt2, a RING finger protein, was first identified as a redox-inducible protein, which, when overexpressed, inhibited apoptosis both in vitro and in vivo. We report here that sensitive to apoptosis gene (SAG, as well as its family member ROC1/Rbxi, bound to the proinactive form of caspase-3 (pro-caspase-3. Binding was likely mediated through F-box protein, β-transducin repeat-containing protein (β-TrCP, which binds to the first 38 amino acids of pro-caspase-3. Importantly, β-TrCP1 expression significantly shortened the protein half-life of pro-caspase-3, whereas expression of a dominant-negative β-TrCP1 mutant with the F-box domain deleted extended it. An in vitro ubiquitination assay showed that SAG/ROC-SCF -Trcp promoted ubiquitination of pro-caspase-3. Furthermore, endogenous levels of pro-caspase-3 were decreased by overexpression of SAG/ROC-SCFβ-TrCP E3 Ub ligases, but increased on siRNA silencing of SAG, regulator of cullin-1 (ROC1, or β-TrCPs, leading to increased apoptosis by etoposide and TNF-related apoptosis-inducing ligand through increased activation of caspase-3. Thus, pro-caspase-3 appears to be a substrate of SAG/ROC-SCFβ-TrCP E3 Ub ligase, which protects cells from apoptosis through increased apoptosis threshold by reducing the basal level of pro-caspase-3.

  2. Expression and biological-clinical significance of hTR, hTERT and CKS2 in washing fluids of patients with bladder cancer

    Directory of Open Access Journals (Sweden)

    Talesa Vincenzo N

    2010-10-01

    Full Text Available Abstract Background at present, pathogenesis of bladder cancer (BC has not been fully elucidated. Aim of this study is to investigate the role of human telomerase RNA (hTR, human telomerase reverse transcriptase (hTERT and CDC28 protein kinase regulatory subunit 2 (CKS2 in bladder carcinogenesis and their possible clinical significance; Methods the transcript levels of hTR, hTERT and CKS2 were quantified by Real time reverse transcriptase chain reaction in exfoliated cells from bladder washings of 36 patients with BC and 58 controls. The statistical significance of differences between BC bearing patients and control groups, in the general as well as in the stratified analysis (superficial or invasive BC, was assessed by Student's t test. Non parametric Receiver Operating Characteristics analysis (ROC was performed to ascertain the accuracy of study variables to discriminate between BC and controls. The clinical value of concomitant examination of hTR, hTERT and CKS2 was evaluated by logistic regression analysis; Results a significant decrease in hTR and a significant increase in hTERT or CKS2 gene expression were found between BC bearing patients and controls, as well as in the subgroups analysis. The area under the curve (AUC indicated an average discrimination power for the three genes, both in the general and subgroups analysis, when singularly considered. The ability to significantly discriminate between superficial and invasive BC was observed only for hTR transcript levels. A combined model including hTR and CKS2 was the best one in BC diagnosis; Conclusions our results, obtained from a sample set particularly rich of exfoliated cells, provide further molecular evidence on the involvement of hTR, hTERT and CKS2 gene expression in BC carcinogenesis. In particular, while hTERT and CKS2 gene expression seems to have a major involvement in the early stages of the disease, hTR gene expression, seems to be more involved in progression. In

  3. Os efeitos da utilização de mensagens persuasivas na forma de condução no trânsito

    OpenAIRE

    Rocha, Janine Cardoso

    2015-01-01

    A utilização de apelos ao medo em mensagens persuasivas tem sido explorada, e se mostrado eficaz, nas questões que envolvem o tabagismo. No entanto, não se evidenciam muitos estudos relacionando mensagens persuasivas com apelo ao medo e sua influência na intenção de condução no trânsito, principalmente no Brasil. Considerando-se que acidentes de trânsito se apresentam como a décima causa de mortes no mundo e a primeira quando se avaliam pessoas com idade entre 15 e 39 anos, evidencia-se a imp...

  4. Enginyeria de tràfic en xarxes de transport òptiques per a entorns d'àrea metropolitana (RPR) i de gran abast (ASON)

    OpenAIRE

    Spadaro, Salvatore

    2005-01-01

    La arquitectura de las redes de transporte actuales está basada en la tecnología de transporte SDH (Synchronous Digital Hierarchy). Las redes SDH se han diseñado y están optimizadas básicamente para el transporte del tráfico de voz. Actualmente, se está experimentando un crecimiento exponencial del volumen de tráfico de datos. Este crecimiento se debe a que el protocolo IP se está consolidando como capa de integración para servicios múltiples, algunos de ellos con requerimientos de Calidad de...

  5. Disección y Análisis de Tráfico de la Arquitectura SNA sobre Redes IP

    OpenAIRE

    Cornet Recchimuzzi, Juan Manuel

    2016-01-01

    Hoy en día todos nuestros dispositivos son capaces de conectarse a una red a través de la cual se comunican con otros terminales. Día a día, a través de las redes, se mueve una cantidad de información enorme, la cual conocemos como tráfico de una red. Para ser capaces de estudiar una red, diagnosticar problemas, prevenir ataques, corregir fallos, etc. es necesario poder investigar el tráfico que se mueve por dicha red. Sin embargo, como decíamos antes, el volumen de datos es inmenso, y rea...

  6. La representación de la violencia en los tráileres de las películas de Walt Disney Pictures

    OpenAIRE

    Garrido Lora, Manuel

    2010-01-01

    Esta investigación analiza la representación de la violencia en los tráileres de 23 películas de animación producidas por Walt Disney Pictures. Mediante la metodología del análisis de contenido y las utilidades propias de la morfología y analítica narrativas, el investigador, con la experiencia previa del análisis de la violencia en los spots publicitarios, expone en este trabajo las cualidades de las acciones violentas presentes en dichos tráileres, y concluye que, atendiendo a investigacion...

  7. Soporte de QoS con 802.11e para tráfico heterogéneo en ambientes MANET

    OpenAIRE

    Murazzo, María Antonia; Rodríguez, Nelson R.; Guevara, Miguel José; Scheffer, María

    2014-01-01

    Hoy en día existe una gran necesidad de mejorar la calidad de servicio (QoS) ofrecida en redes móviles Ad Hoc (Mobile Ad-Hoc Networks -MANET-) que actualmente sólo ofrecen servicio best effort. Esto posee gran impacto en las aplicaciones que se corren, las cuales generan tráficos con diferentes requerimientos de recursos de la red. El presente trabajo tiene como objetivo fundamental analizar el comportamiento de la implementación de QoS en la sub capa MAC mediante 802.11e en ambientes con trá...

  8. Modelo de Detección de Datos Atípicos de Tráfico. Autopista C-58, Barcelona

    OpenAIRE

    Ahumada Valenzuela, Pamela

    2011-01-01

    Desde al año 2009, en la autopista C-31 y C32, pertenecientes a los accesos sur de la ciudad de Barcelona, comienzan a operar con una nueva modalidad en la gestión de tráfico, con “Velocidad Variable”. Dicho límite de velocidad se establece por medio de un algoritmo, el que es alimentado por diferentes variables, entre ellas, la información aportada los medios electrónicos instalados en dichas autopistas, los detectores. A partir de esta incorporación en la gestión de tráfico de carreteras...

  9. Cambios en la ecología trófica de los depredadores apicales del Mar Argentino durante el Holoceno

    OpenAIRE

    Saporiti, Fabiana

    2014-01-01

    [spa] El Mar Argentino ha sufrido un impacto humano creciente desde el Holoceno medio hasta hoy en día, fruto del cual se han producido importantes cambios en los niveles más altos de la red trófica. Las actividades extractivas (caza y pesca), tanto la aborigen como la actual, tienen la tendencia a explotar las especies de mayor tamaño, produciendo el efecto conocido en gestión de pesquerías como “fishing down the food web”. En otras palabras el impacto humano llevaría a cadenas tróficas más ...

  10. Estructura de la comunidad de moluscos y relaciones tróficas en el litoral rocoso del estado Sucre, Venezuela

    Directory of Open Access Journals (Sweden)

    Johanna Fernández

    2006-12-01

    Full Text Available Se analizó la estructura de la comunidad de moluscos y sus relaciones tróficas en seis localidades del litoral rocoso con diferentes grados de exposición al oleaje (área expuesta y área protegida, en el Estado Sucre, Venezuela. El muestreo se llevó a cabo durante el período de marzo 2003 a febrero 2004. La recolección del material biológico se realizó de forma manual con ayuda de una espátula, dentro de una cuadrícula de 0.25 m², estableciéndose tres zonas: supra, medio e infralitoral. Los organismos fueron preservados en frascos con formalina al 10% para su posterior análisis. En el laboratorio fueron identificados, contados, y pesados en una balanza de 0.001g de precisión. Se determinó la abundancia total de especies, biomasa, constancia específica y por medio de una revisión bibliográfica se le asignó a cada especie su categoría trófica, clasificándolos en: herbívoros, filtradores, carnívoros y herbívoros -filtradores. Se obtuvo un total de 14 581 individuos (6 397.945 g representado por 68 especies correspondientes a las clases Gastropoda (39, Bivalvia (23 y Polyplacophora (6; contenidas en nueve órdenes y 31 familias. Los herbívoros fueron el grupo dominante (49%, seguido por filtradores (37%, carnívoros (13 % y herbívoros-filtradores (1%. Las especies herbívoras y herbívoras-filtradoras dominaron en el área protegida, mientras que en el área expuesta, fueron las carnívoras y filtradoras. Las especies constantes en las seis localidades durante el período de estudio fueron Planaxis nucleus, Mitrella ocellata, M. nycteis, Littorina interrupta, Tegula fasciata, Acmaea leucopleura, Ostrea equestris y Chiton squamosus. La distribución de los moluscos y los diferentes grupos tróficos, pueden estar controlados por adaptaciones morfológicas, así como el nivel de exposición al oleaje y composición del sustrato.Mollusc community structure and trophic relations in the rochy littoral zone in Sucre State

  11. Controle sanitário de fronteiras: trânsito internacional de pessoas na Copa do Mundo de 2014

    Directory of Open Access Journals (Sweden)

    Aline Daiane dos Reis LIMA

    2013-04-01

    Full Text Available Enquanto as viagens e o comércio internacionais trazem muitos benefícios à saúde ligados ao desenvolvimento econômico, eles também podem causar riscos à saúde pública que podem se disseminar internacionalmente em aeroportos, portos e fronteiras terrestres por meio de pessoas, animais, alimentos, bagagens, cargas, meios de transporte, mercadorias e encomendas postais. Devido ao aumento do tráfego de pessoas durante a Copa do Mundo de 2014 que acontecerá no Brasil, percebe-se a necessidade da efetiva aplicação do Regulamento Sanitário Internacional (2005 para que seja garantido o direito fundamental a saúde da população brasileira e aos visitantes por meio da identificação de emergências de saúde pública de importância internacional e das respostas a tais eventos. ABSTRACT While international travel and trade bring many health benefits linked to economic development, they may also cause public health risks that can spread internationally at airports, ports and ground crossings through people, animals, food, baggage, cargo, containers, goods and postal parcels. Due to the increased traffic of people during the 2014 World Cup to be held in Brazil, one realizes the need to apply the definitions of the International Health Regulations (2005 to be guaranteed the fundamental right to health of the population and visitors by identifying public health emergencies of international concern and the answers to these events. RESUMEN Mientras que los viajes y el comercio internacionales trae muchos beneficios de salud relacionados con el desarrollo económico, sino que también pueden causar riesgos de salud pública que pueden propagarse a nivel internacional en los aeropuertos, puertos y fronteras terrestres a través de personas, animales, alimentos, equipajes, cargas, medios de transporte, mercancías y paquetes postales. Debido al aumento del tráfico de personas durante la Copa del Mundo 2014 que se celebrará en Brasil, se da

  12. Estudo de caso de três espécies de plantas bioindicadoras de solos salinos

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    Mercia Fonseca Carvalho

    2015-07-01

    Full Text Available Bioindicadores, de uma maneira geral, são seres vivos de natureza diversa, vegetais ou animais, utilizados para analisar a qualidade de um determinado ambiente. A degradação ambiental do solo pela salinidade é um problema muito antigo e de extensão mundial, geralmente, mais pronunciado nas regiões áridas e semi-áridas. As plantas que se desenvolvem em áreas com elevadas concentrações de sais são chamadas de halófitas, e algumas delas são usadas na recuperar desses solos. O objetivo desse trabalho é analisar três espécies de plantas resistentes ao estresse salino gerar recomendações a respeito das mesmas, disponibilizando uma indicação de espécie que possa recuperar o ambiente salinizado. Foram selecionadas aleatoriamente três espécies de plantas resistentes a salinidade Copernicia prunifera, Atriplex nummularia L. e Gossypium hirsutum L, as mesmas foram analisados por uma planilha com características que identificam um bioindicador ideal e em seguida as espécies foram avaliadas de acordo com sua fisiologia e etiologia. Embora as propriedades da espécie A. nummularia tenha se destacado por recuperar os solos salinizados a espécie Copernicia prunifera foi considerada como um bioindicador ideal. Recomendam-se ainda estudos mais aprofundados acerca desse assunto.Case study of three species of saline soil bioindicatorsAbstract: Bioindicators, in general, living organisms are diverse in nature, plant or animal used to assess the quality of a given environment. Environmental degradation by soil salinity is a very old problem and expanse world generally more pronounced in arid and semi-arid regions. Plants that thrive in areas with high concentrations of salts are called halophytes, and some of them are used in recovering these soils. The aim of this work is to analyze three species of plants resistant to salt stress generate recommendations regarding the same, providing an indication of species that can restore the

  13. O papel dos Pontos de Troca de Tráfego em políticas e regulação da banda larga

    Directory of Open Access Journals (Sweden)

    Daniel Brandão Cavalcanti

    2011-05-01

    Full Text Available Novos investimentos em infraestrutura de redes de transporte (backbones para a internet e a necessidade de trocar tráfego com backbones existentes, tanto na modalidade de trânsito como na de peering, indicam a crescente relevância de um elemento-chave nessa arquitetura – o Ponto de Troca de Tráfego (PTT. Há muito poucos PTT disponíveis hoje em dia, principalmente se considerado o vertiginoso crescimento no número de sistemas autônomos anunciados. Os PTT implantados por redes de pesquisa demonstram que um acréscimo expressivo no número desses pontos teria o efeito de melhorar a topologia da internet, aumentar a conectividade, reduzir a latência e o custo de troca de tráfego. Adicionalmente, os PTT podem ser o local mais eficiente para a oferta de determinados serviços. Este trabalho aborda as possibilidades de ação regulatória para estimular a implementação dos PTT e para assegurar que seus benefícios sejam amplamente compartilhados.

  14. Is the Eating Disorder Questionnaire-Online (EDQ-O) a valid diagnostic instrument for the DSM-IV-TR classification of eating disorders?

    NARCIS (Netherlands)

    ter Huurne, Elke D.; de Haan, Hein A.; ten Napel-Schutz, Marieke C.; Postel, Marloes Gerda; Menting, Juliane; van der Palen, Jacobus Adrianus Maria; Vroling, Maartje S.; de Jong, Cor A.J.

    2015-01-01

    Background The Eating Disorder Questionnaire-Online (EDQ-O) is an online self-report questionnaire, which was developed specifically to provide a DSM-IV-TR classification of anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), and eating disorder not otherwise specified (EDNOS),

  15. Reliability and validity of the DSM-IV-TR and proposed DSM-5 criteria for pedophilia: Implications for the ICD-11 and the next DSM.

    Science.gov (United States)

    Seto, Michael C; Fedoroff, J Paul; Bradford, John M; Knack, Natasha; Rodrigues, Nicole C; Curry, Susan; Booth, Brad; Gray, Jonathan; Cameron, Colin; Bourget, Dominique; Messina, Sarina; James, Elizabeth; Watson, Diane; Gulati, Sanjiv; Balmaceda, Rufino; Ahmed, Adekunle G

    We tested the inter-rater reliability and criterion-related validity of the DSM-IV-TR pedophilia diagnosis and proposed DSM-5 pedohebephilia diagnosis in a sample of 79 men who had committed child pornography offenses, contact sexual offenses against children, or who were referred because of concerns about whether they had a sexual interest in children. Participants were evaluated by two independent psychiatrists with an interview and questionnaire regarding demographic characteristics, sexual history, and self-reported sexual interests; they also completed phallometric and visual reaction time testing. Kappa was .59 for ever meeting DSM-IV-TR criteria for pedophilia and .52 for ever meeting the proposed DSM-5 criteria for pedohebephilia. Ever meeting DSM-IV-TR diagnosis was significantly related to self-reported index of sexual interest in children (highest AUC=.81, 95% CI=.70-.91, pDSM-5 "diagnosis" was similarly related to self-report (AUC=.84, 95% CI=.74-.94, pDSM-5 criteria, we believe these results suggest the revision of DSM-5 and development of ICD-11 could benefit from drawing on the current DSM-5 criteria, which are essentially the same as DSM-IV-TR except for a distinction between having a paraphilia (the interest) and a paraphilic disorder (the paraphilia plus clinically significant distress or impairment). Copyright © 2016. Published by Elsevier Ltd.

  16. Diagnostic Classification of Eating Disorders in Children and Adolescents: How Does DSM-IV-TR Compare to Empirically-Derived Categories?

    Science.gov (United States)

    Eddy, Kamryn T.; Le Grange, Daniel; Crosby, Ross D.; Hoste, Renee Rienecke; Doyle, Angela Celio; Smyth, Angela; Herzog, David B.

    2010-01-01

    Objective: The purpose of this study was to empirically derive eating disorder phenotypes in a clinical sample of children and adolescents using latent profile analysis (LPA), and to compare these latent profile (LP) groups to the DSM-IV-TR eating disorder categories. Method: Eating disorder symptom data collected from 401 youth (aged 7 through 19…

  17. Is the Eating Disorder Questionnaire-Online (EDQ-O) a valid diagnostic instrument for the DSM-IV-TR classification of eating disorders?

    NARCIS (Netherlands)

    Huurne, E.D. ter; Haan, H.A. de; Napel-Schutz, M.C. ten; Postel, M.G.; Menting, J.; Palen, J.A.M. van der; Vroling, M.S.; Jong, C.A.J. de

    2015-01-01

    Background: The Eating Disorder Questionnaire-Online (EDQ-O) is an online self-report questionnaire, which was developed specifically to provide a DSM-IV-TR classification of anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), and eating disorder not otherwise specified

  18. The role of subsite +2 of the Trichoderma reesei beta-mannanase TrMan5A in hydrolysis and transglycosylation

    DEFF Research Database (Denmark)

    Rosengren, Anna; Hägglund, Per; Anderson, Lars Steen

    2012-01-01

    The N-terminal catalytic module of beta-mannanase TrMan5A from the filamentous fungus Trichoderma reesei is classified into family 5 of glycoside hydrolases. It is further classified in clan A with a (beta/alpha)(8) barrel configuration and has two catalytic glutamates (E169 and E276). It has at ...

  19. SCFβ-TrCP ubiquitin ligase-mediated processing of NF-κB p105 requires phosphorylation of its C-terminus by IκB kinase

    Science.gov (United States)

    Orian, Amir; Gonen, Hedva; Bercovich, Beatrice; Fajerman, Ifat; Eytan, Esther; Israël, Alain; Mercurio, Frank; Iwai, Kazuhiro; Schwartz, Alan L.; Ciechanover, Aaron

    2000-01-01

    Processing of the p105 precursor to form the active subunit p50 of the NF-κB transcription factor is a unique case in which the ubiquitin system is involved in limited processing rather than in complete destruction of the target substrate. A glycine-rich region along with a downstream acidic domain have been demonstrated to be essential for processing. Here we demonstrate that following IκB kinase (IκK)-mediated phosphorylation, the C-terminal domain of p105 (residues 918–934) serves as a recognition motif for the SCFβ-TrCP ubiquitin ligase. Expression of IκKβ dramatically increases processing of wild-type p105, but not of p105-Δ918–934. Dominant-negative β-TrCP inhibits IκK-dependent processing. Furthermore, the ligase and wild-type p105 but not p105-Δ918–934 associate physically following phosphorylation. In vitro, SCFβ-TrCP specifically conjugates and promotes processing of phosphorylated p105. Importantly, the TrCP recognition motif in p105 is different from that described for IκBs, β-catenin and human immunodeficiency virus type 1 Vpu. Since p105-Δ918–934 is also conjugated and processed, it appears that p105 can be recognized under different physiological conditions by two different ligases, targeting two distinct recognition motifs. PMID:10835356

  20. Brief Report: An Exploratory Study Comparing Diagnostic Outcomes for Autism Spectrum Disorders under DSM-IV-TR with the Proposed DSM-5 Revision

    Science.gov (United States)

    Gibbs, Vicki; Aldridge, Fiona; Chandler, Felicity; Witzlsperger, Ellen; Smith, Karen

    2012-01-01

    The proposed revision for Autism spectrum disorders (ASDs) in the Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition (DSM-5) represents a shift from the Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition, Text Revision (DSM-IV-TR). As the proposed DSM-5 criteria require a higher minimum number of symptoms to be…

  1. The Relationship between the "Childhood Autism Rating Scale: Second Edition" and Clinical Diagnosis Utilizing the DSM-IV-TR and the DSM-5

    Science.gov (United States)

    Dawkins, Tamara; Meyer, Allison T.; Van Bourgondien, Mary E.

    2016-01-01

    "The Childhood Autism Rating Scale, Second Edition" (CARS2; 2010) includes two rating scales; the CARS2-Standard Version (CARS2-ST) and the newly developed CARS2-High Functioning Version (CARS2-HF). To assess the diagnostic agreement between the CARS2 and DSM-IV-TR versus DSM-5 criteria for Autism Spectrum Disorder (ASD), clinicians at…

  2. Logística Reversa: Uma Análise Comparativa entre Três Processos Reversos de Resíduos Vítreos

    Directory of Open Access Journals (Sweden)

    Joaquim Carlos Lourenço

    2012-12-01

    Full Text Available O presente estudo tem por objetivo fazer uma análise comparativa entre três processos de logística reversa de resíduos vítreos. Para tanto, foi adotado como método, a pesquisa descritiva, e para coleta de dados a pesquisa bibliográfica. Na análise comparativa dos processos foram utilizados destaques que identificam os itens: Convergência entre os três processos; Divergência entre os três processos; e convergência parcial entre os processos. Assim, para cada item em análise, foi aplicado uma dessas três dimensões para comparar o processo reverso descrito nos estudos. O modelo de análise foi adaptado de Miranda et al. (2003. Os resultados encontrados apontam que os processos logísticos reversos descritos proporcionam vantagens econômicas e ambientais para as empresas. Por outro lado, a implantação dos processos reversos demanda investimentos altos, bem como o mapeamento e padronização dos processos de produção, aspectos estes que supostamente poderão contribuir a continuidade do empreendimento quando adotar esse tipo de prática empresarial.

  3. Distrofia muscular familial: A propósito de três casos da moléstia de Steinert

    Directory of Open Access Journals (Sweden)

    Oswaldo Freitas Julião

    1943-09-01

    Full Text Available Os AA. apresentam as observações clínicas de três irmãos portadores de Distrofia Miotônica. Depois de justificarem esse diagnóstico (baseado na presença de amiotrofias, fenômenos miotônicos, persistência de um sulco determinado pela percussão de massas musculares, atrofia testicular com azoospermia, catarata, hipersecreção lacrimal, etc., salientam algumas particularidades dos casos em estudo, chamando especialmente a atenção para a importância das alterações elétricas observadas (contração lenta, reação fibrilar, etc. Estas alterações da excitabilidade elétrica, aliadas à presença de contrações fibrilares e de mioedema, poderiam indicar a existência de comprometimento das células das pontas anteriores da medula (lesão nuclear, hipótese que é discutida pelos AA. Finalmente, são expostas as conclusões gerais relativas aos casos apresentados.

  4. Tráfico y tenencia ilegal de fauna silvestre en el departamento de Boyacá

    Directory of Open Access Journals (Sweden)

    Alejandro Cabrejo Bello

    2010-10-01

    Full Text Available Con el fin de establecer cuáles son los principales grupos taxonómicos, suparticipación y las ciudades con mayores índices de tráfico y tenencia ilegal de vida silvestre en el departamento de Boyacá, jurisdicción de la Corporación Autónoma Regional de Boyacá- Corpoboyacá, se tomaron reportes de la base de datos de dicha entidad entre los años 2004 y 2008. Se hallaron registros de 398 individuos decomisados por parte de la autoridad ambiental y otros por entregas voluntarias. El grupo con mayor incidencia fue el de las aves con 58%,seguido por los reptiles con 26% y en tercer lugar los mamíferos con el 16% de los registros. Se observó que las tres principales ciudades del departamento (Tunja, Duitama y Sogamoso reportan las frecuencias más elevadas de incautaciones. Puerto Boyacá, también registra un número elevado de decomisos. Dentro de los tres grupos mencionados, las especies más afectadas correspondena los órdenes Psitaciformes, Primates y Testudínata, por lo cual merecen principal atención. Se recomienda además, implementar planes de conservación y emprender actividades de educación ambiental encaminadas a la utilización sostenible de la fauna en general.

  5. O rei do pop e as nuances da pós-modernidade trágica

    Directory of Open Access Journals (Sweden)

    Nayana M. Moraes

    2010-12-01

    Full Text Available Este artigo mostra a relação das celebridades com os aspectos trágicos de suas vidas e o envolvimento dos fãs a partir da catarse. Todos estes termos imbricados dialogarão com um dos gêneros literários mais antigos: a tragédia grega. Esta permeará um entendimento acerca da forma com que nós, espectadores, analisamos alguns famosos, bem como sua influência na indústria do entretenimento. Neste contexto, alguns deles não conseguem adquirir um equilíbrio entre a fama e sua vida pessoal, que cai diante de sua hybris (desequilíbrio interno. E um destes artistas, considerado o mito da música e do entretenimento, compreenderá esta discussão: Michael Jackson. O filósofo grego Aristóteles discutiu e revigorou a importância e verossimilhança desta literatura no ser humano. Veremos, entretanto, que mesmo com estes conflitos, o mito permanece.

  6. The association between diabetes mellitus, glucose, and chronic musculoskeletal complaints. Results from the Nord-Trøndelag Health Study

    Directory of Open Access Journals (Sweden)

    Zwart John-Anker

    2008-12-01

    Full Text Available Abstract Background The relationship between diabetes mellitus (DM and chronic musculoskeletal complaints (MSCs is unclear. The aim of this study was to investigate the association between DM, non-fasting glucose and chronic MSCs defined as pain and/or stiffness ≥ 3 months during the past year in the general adult population. Methods The results were based on cross-sectional data from 64,785 men and women (aged ≥ 20 years who participated in the Nord-Trøndelag Health Survey, which included 1,940 individuals with known DM. Associations were assessed using multiple logistic regression, estimating prevalence odds ratio (OR with 95% confidence intervals (CIs. Results High non-fasting glucose was associated with a lower prevalence of chronic MSCs compared to a low glucose level. DM was associated with higher prevalence of chronic MSCs, in particular chronic widespread MSCs. In the multivariate analysis, adjusting for glucose level, BMI, age, gender and physical activity, chronic widespread MSCs was 1.6 times more likely (OR = 1.6, 95% CI 1.2–2.2 among individuals Conclusion In this cross-sectional study a high non-fasting glucose was associated with lower prevalence of chronic MSCs. Among individuals with known DM chronic widespread MSCs were more likely.

  7. Três casamentos e algumas reflexões: Notas sobre conjugalidade envolvendo travestis que se prostituem

    Directory of Open Access Journals (Sweden)

    Larissa Pelúcio

    2006-05-01

    Full Text Available http://dx.doi.org/10.1590/S0104-026X2006000200012 A partir de uma abordagem antropológica que dialoga com a teoria queer, analisamse três experiências de conjugalidade envolvendo travestis que se prostituem, discutindo-se os limites dessas relações, impostos pela visão de mundo que orienta as travestis, pessoas pertencentes em sua maioria às camadas populares e, de acordo com a hipótese que se coloca, tributárias de uma visão de mundo holista. Assim, observa-se que as relações conjugais vêm fortemente orientadas por perspectivas essencialista quanto ao sexo e ao gênero, atribuindo papéis rigidamente estabelecidos para cada parceiro. Ao naturalizar o sexo que exige um gênero supostamente coerente a essa anatomia que elas simplesmente não aceitam como destino, mantêm-se atadas à matriz heteronormatizadora. Informadas por uma gramática de conjugalidade heterossexual, elas encontram dificuldades em elaborar um outro léxico para as relações conjugais.

  8. Desenvolvimento larval de Chrysoperla externa alimentada com Aphis gossypii provenientes de três cultivares de algodoeiro

    Directory of Open Access Journals (Sweden)

    Eunice Cláudia Schlick-Souza

    2011-10-01

    Full Text Available O objetivo deste trabalho foi avaliar os aspectos biológicos de Chrysoperla externa alimentadas com Aphis gossypii provenientes de três cultivares de algodoeiro (FMT 701, Acala 90 e Delta Opal. O experimento foi conduzido no Laboratório de Fitossanidade da Universidade Estadual de Mato Grosso do Sul (UEMS, Unidade de Cassilândia (MS. Os adultos de C. externa foram mantidos em gaiolas de PVC, em sala climatizada. As larvas do predador foram individualizadas em placas de Petri e alimentadas diariamente com pulgões advindos das diferentes cultivares. Larvas que se alimentaram de indíviduos da cultivar FMT 701 apresentaram a viabilidade menor do que as que alimentaram dos afídeos criados nas cultivares Delta Opal e Acala 90. Observou-se redução do consumo diário nas larvas de terceiro ínstar que se alimentaram dos pulgões advindos da cultivar Acala 90. Consequentemente, larvas supridas com pulgões criados nas cultivares Delta Opal e Acala 90, tiveram menor peso, 3,60 e 3,90 mg respectivamente, diferindo significativamente da FMT 701. De modo geral, é possível a utilização de C. externa no controle de A. gossypii nas cultivares estudadas.

  9. Um método para o planejamento do roteamento contingencial de tráfego aéreo

    Directory of Open Access Journals (Sweden)

    Leonardo Guerra de Rezende Guedes

    2008-10-01

    Full Text Available Neste trabalho, considera-se o problema logístico de rotear as aeronaves de uma companhia para que esta possa ao longo do tempo voltar seus vôos aos horários definidos pela Agência Nacional de Aviação Civil - ANAC. Para tal é utilizada a representação em Redes de Petri a qual permite o controle do funcionamento dos vôos da companhia, sendo possível controlar o movimento dos aviões pela rede assim como o tempo do vôo. A construção dos planos necessários ao retorno dos horários da companhia sugere uma busca por seqüências de vôos sobre a Rede de Petri. A técnica a ser utilizada para ser feita esta busca são os Algoritmos Genéticos. Este artigo apresenta a aplicação conjunto de Redes de Petri e Algoritmos Genéticos na resolução do problema de roteamento contingencial de tráfego aéreo objetivando ao restauração das rotas e horários de vôos padrões.

  10. SGT1 regulates Akt signaling by promoting beta-TrCP-dependent PHLPP1 degradation in gastric cancer cells.

    Science.gov (United States)

    Gao, Ganglong; Kun, Tao; Sheng, Youhua; Qian, Min; Kong, Fanzhi; Liu, Xiaoguang; Yu, Zhenfeng; Zhang, Haiqin; Zhang, Qiang; Gu, Jianping; Zhang, Xueli

    2013-04-01

    SGT1 (suppressor of G2 allele of Skp1) plays a role in various cellular processes including kinetochore assembly and protein ubiquitination by interacting with Skp1, a component of SCF E3 ligase complex. However, the function of SGT1 in cancer is largely unknown. Here, we showed that SGT1 was over-expressed in gastric cancer tissues and silencing of SGT1 by siRNAs significantly inhibited the growth and colony formation of gastric cancer cells. We further showed that SGT1 could regulate Akt signaling pathway by modulating Akt ser473 phosphorylation status. Moreover, we found that SGT1 was able to regulate the stability of PHLPP1, which is the direct phosphatase for Akt ser473 phosphorylation. Immunoprecipitation assay revealed that SGT1 could enhance the binding between PHLPP1 and beta-TrCP which has been documented to be able to target PHLPP1 for destruction. Decreased PHLPP1 in SGT1 over-expressed gastric cancer cells failed to dephosphorylate Akt and resulted in increased Akt ser473 phosphorylation and amplified downstream Akt signaling. Thus, our data revealed a previously uncovered role of SGT1 in gastric cancer development, and suggested that SGT1 could be a promising anti-cancer target to against gastric cancer.

  11. Fatores associados ao óbito de motociclistas nas ocorrências de trânsito

    Directory of Open Access Journals (Sweden)

    Nelson Luiz Batista de Oliveira

    2012-12-01

    Full Text Available Para identificar fatores associados ao óbito em motociclistas envolvidos em ocorrências de trânsito, em Maringá-PR, foi realizado estudo retrospectivo incluindo os motociclistas envolvidos em acidentes no ano de 2004. As fontes de dados foram os registros da Polícia Militar, do SIATE e do Instituto Médico Legal. Foram realizadas análises bivariadas e regressão logística binária. Identificaram-se 2.362 motociclistas nos Boletins de Ocorrência e, destes, 1.743 tinham registros nos Relatórios de Atendimento do Socorrista. As vítimas fatais diferiram das demais quanto à faixa etária, ao local de residência, ao tempo de habilitação e as suas condições fisiológicas na cena da ocorrência. No modelo final permaneceram as seguintes variáveis: Escala de Coma de Glasgow (ECGl, Revised Trauma Score (RTS, pulso e saturação de O2 no sangue. As condições fisiológicas das vítimas na cena do acidente se destacaram no modelo final e a ECGl superou o RTS na associação com óbito.

  12. El tráfico de influencias en la España franquista: decisiones públicas, beneficios privados

    Directory of Open Access Journals (Sweden)

    Francisco Javier Fernández Roca

    2012-08-01

    Full Text Available En la España del primer franquismo, la política económica autárquica y el marco institucional intervencionista provocaron que los agentes económicos no se comportaran buscando la eficiencia económica, sino como buscadores de rentas. En este artículo se estudia, en primer lugar, el tráfico de influencias en las entregas directas de activos o en las asignaciones sesgadas de bienes, legitimados de alguna forma, por parte del poder público; en segundo lugar, se analiza cómo operaron las estructuras administrativas y burocráticas del Estado. Finalmente, se estudia la generación de beneficios particulares obtenidos desde los programas económicos y desde las normativas de la política económica.During the first regime of the Franco dictatorship, the economic policy implemented in Spain was autarky. This policy and the high level of government interventionism lead the economic agents to behave as rent-seekers instead of seeking efficiency. In this paper, we firstly study the peddling of political favors not only through direct deliveries of assets but also trough the slanted assignments of goods. These two aspects were legitimized, in some way, by the State. Secondly, we analyze the role played by the government administrative and bureaucratic structures. Lastly, we study the private profits obtained from both economic programs and the regulations established by the economic policy.

  13. Plagijavimas reklamoje: kūrybinio mąstymo trūkumas ar perpildytos rinkos pasekmė?

    Directory of Open Access Journals (Sweden)

    Ieva Mantė Valivonytė

    2013-10-01

    Full Text Available Straipsnyje nagrinėjama dažnėjančio plagijavimo reiškinio lietuviškose reklamose problema, pateikiamaplagijavimo sąvokos apibrėžtis ir atsiradimo priežastys, supažindinama su reklamos agentūrų vykdomoskūrybinės veiklos procesais, užsienio šalių šioje srityje patirtimi. Pateikiami išanalizuoti lietuviškų reklamosagentūrų kūrybinio proceso ypatumai kuriant reklamines kampanijas ir įvardyti veiksniai, lemiantys plagijavimoatsiradimą.Šis darbas supažindina su lietuviškų reklamos agentūrų kūrybinio proceso ypatybėmis, plagijavimo atvejais,kūrybinio mąstymo trūkumo priežastimis ir šios problemos sprendimo būdais. Taip pat su perpildytos reklamosrinkos padėtimi ekonominės krizės metu ir pagrindiniu veiksniu, lemiančiu plagijavimo atsiradimą – konkurencinekova tarp įvairaus verslo šakų, kuri reikalauja kūrybiškumo kuriant verslą ir tam tikrą produkciją.

  14. Technical review of WSRC-TR-93-614 criticality safety evaluation for disassembly basin sand filter

    International Nuclear Information System (INIS)

    Reed, R.L.

    1994-01-01

    The study documented in WSRC-TR-93-614 performed an evaluation of the criticality potential associated with the Disassembly Basin Sand Filter for K and L Areas. The document reviewed incorporated results of calculations documented in the engineering calculation N-CLC-K-00151. Analyses of the contents of disassembly basin sludge has indicated that the sludge contains fissile material in excess of subcritical mass limits as specified in ANSI/ANS standards. Previous studies had determined that the fissile material can not collect into a critical configuration in the basin. Since the sand filter is intended to remove suspended particles from the basin water and could serve as a mechanism to collect the fissile material into a critical configuration, the study examined conditions under which criticality could occur in the sand filter. The study shows that criticality is not considered possible in the sand filter. This review emphasized the technical accuracy and presentation of the evaluation. The evaluation was also examined for the elements required for NCSEs. The review was performed in accordance with the NRTSC technical review requirements and procedures and the E7 Manual technical review requirements. The technical review (per the E7 manual) of the engineering calculation (N-CLC-K-0 1 5 1) was previously performed by this reviewer

  15. Controle sanitário de fronteiras: trânsito internacional de pessoas na Copa do Mundo de 2014

    Directory of Open Access Journals (Sweden)

    Aline Daiane dos Reis Lima

    2013-12-01

    Full Text Available Enquanto as viagens e o comércio internacionais trazem muitos benefícios à saúde ligados ao desenvolvimento econômico, eles também podem causar riscos à saúde pública que podem se disseminar internacionalmente em aeroportos, portos e fronteiras terrestres por meio de pessoas, animais, alimentos, bagagens, cargas, meios de transporte, mercadorias e encomendas postais. Devido ao aumento do tráfego de pessoas durante a Copa do Mundo de 2014 que acontecerá no Brasil, percebe-se a necessidade da efetiva aplicação do Regulamento Sanitário Internacional (2005 para que seja garantido o direito fundamental a saúde da população brasileira e aos visitantes por meio da identificação de emergências de saúde pública de importância internacional e das respostas a tais eventos.

  16. Determination and assessment of the concentration limits to be used in SR-Can. Supplement to TR-06-32

    International Nuclear Information System (INIS)

    Grive, Mireia; Domenech, Cristina; Montoya, Vanessa; Garcia, David; Duro, Lara

    2010-09-01

    This document complements and updates the report TR-06-32, Determination and assessment of the concentration limits to be used in SR-Can, in which the solubility limits of different radionuclides in the near field system and under the different scenarios selected by SKB were assessed. Since 2006, several important changes in different fields affecting solubility assessment calculations have been reported. These changes basically concern some of the thermodynamic data used in the calculations and the groundwater compositions for scenarios of interest defined by SKB. In this document we update the thermodynamic data corresponding to Ni, Zr, Th and U and we describe the thermodynamic database selected for Pb. This document also reports the update of the assessment of the concentration limits to be used in SR-Can, which has been done considering the recent thermodynamic database updates and the new groundwater compositions of interest supplied by SKB. Finally, we also present the Simple Functions spreadsheet tool, born from the need of having a confident and easy-to-handle tool to calculate solubility limits of some radionuclides under determined conditions in an agile and relatively fast manner

  17. Família interdita: transgeracionalidade e subjetivação em três obras ficcionais

    Directory of Open Access Journals (Sweden)

    Fabio Scorsolini-Comin

    2012-06-01

    Full Text Available O objetivo deste estudo foi discutir a transmissão psíquica geracional em duas obras do escritor Mia Couto: Antes de nascer o mundo (2009 e Um rio chamado tempo, uma casa chamada terra (2003, e no conto A terceira margem do rio, de Guimarães Rosa (1962. As três obras são narradas pelos filhos e destacam a família como epicentro de uma trama de segredos, interditos e culpabilizações transmitidos de uma geração a outra, possibilitando a compreensão de que o seio familiar permite não apenas a organização das experiências emocionais, mas a também a transmissão de aspectos intersubjetivos aos quais nem sempre as personagens têm acesso. Os segredos ou a não revelação das verdadeiras histórias dos personagens são apenas uma das formas de transmissão, pois, mesmo ocultando o interditado, transfere-se algo, de modo que o não revelar também é uma maneira de destacar o interdito, aquilo que ainda não foi elaborado e que, por conseguinte, não recebeu inscrição psíquica.

  18. High frequency P(VDF-TrFE) copolymer broadband annular array ultrasound transducers using high density flexible circuit interconnect

    Science.gov (United States)

    Gottlieb, Emanuel J.; Cannata, Jonathan M.; Hu, Chang Hong; Shung, K. K.

    2005-04-01

    A kerfless eight element high frequency ultrasound annular array transducer using 9 μm P(VDF-TrFE) bonded to a high density flexible interconnect was fabricated. The flexible circuit composed of Kapton polyimide film with gold electrode pattern of equal area annuli apertures on the top side of a 50 μm thick Kapton polyimide film. Each element had several 30 μm diameter electroplated vias that connected to electrode traces on the bottom side of the Kapton polyimide film. There was a 30 μm spacing between elements. The total aperture of the array was 3.12 mm. The transducer's performance has been modeled by implementing the Redwood version of the Mason model into PSpice and using the Krimholtz, Leedom and Matthaei (KLM) model utilized in the commercial software PiezoCAD. The transducer"s performance was evaluated by measuring the electrical impedance with a HP 4194 impedance analyzer, pulse echo response using a Panametrics 5900 pulser/receiver and crosstalk measurement for each element in the array. The measured electrical impedance for each element was 540 Ω and -84° phase. In order to improve device sensitivity an inductor was attached in series with each element to reduce the insertion loss to 33 dB. The measured average center frequency and bandwidth of each element was 55 MHz and 50% respectively. The measured crosstalk at the center frequency was -45 dB in water.

  19. Estructura, dimensiones y producción de semilla de malezas del trópico húmedo

    Directory of Open Access Journals (Sweden)

    Juan Calder\\u00F3n

    2000-01-01

    Full Text Available Estructura, dimensiones y producción de propágulos sexuales de malezas del trópico húmedo. Los objetivos de este trabajo fueron determinar las dimensiones promedio, describir la estructura externa de las semillas, frutos o espiguillas y estimar el número producido por planta y por gramo, de doce especies de malezas. Se elaboraron esquemas de los propágulos. En las dicotiledóneas estudiadas, el número promedio de semillas por planta varió de 1290 en Asclepias curassavica hasta 195008 en Ludwigia sp. La segunda especie con más elevado número promedio de semillas por planta fue Sida rhombifolia (7962 seguida por Ipomoea sp.(2876. Hyptis capitata mostró mayor número promedio de cabezuelas por planta (341 que Bidens pilosa (106 y que Emilia sonchifolia (61. Mimosa pudica produjo un promedio de 3.3 semillas por fruto. En las Poaceae, Paspalum conjugatum y P. Virgatum produjeron mayor número de espiguillas por rama floral (381 y 1185 respectivamente que Ischaemum indicum (81 y que Rottboellia cochinchinensis (14. Se menciona la anemocoria, la hidrocoria y la zoocoria como mecanismos que contribuyen en la dispersión de estas especies

  20. The Eurasian eagle-owl (Bubo bubo diet in the Trøndelag region (Central Norway

    Directory of Open Access Journals (Sweden)

    Obuch Ján

    2016-12-01

    Full Text Available Between 2008 and 2015 we collected pellets of the Eurasian eagle-owl (Bubo bubo in the Trøndelag region of central Norway and identified the food remains in these samples. We collected material at 45 sites with samples from a total of 76 nests. Some of the samples were from older and already abandoned nests, but at several sites we also found and collected fresh B. bubo pellets. In total 40,766 items of prey were identified from the osteological material. The most dominant food components were mammals (Mammalia, 25 species, 63.5%. The species representation of birds was very diverse (Aves, more than 150 species, 19.4%. Of amphibians (Amphibia, 1 6.8%, the well-represented species were Rana temporaria. Fish (Pisces, 0.3% were represented rarely, while invertebrates were represented only sporadically (Invertebrata, 0.05%. A special composition was found in the diet spectra of the mammals and birds in the mountainous areas at altitudes between 220-780 m above sea level. The highest proportion of frogs was found in areas in the proximity of the mainland shore. On the northern islands located near the coast a significant proportion of the B. bubo diet consisted of rodents (Rodentia. On the more isolated southern islands of Frøya, Hitra and Storfosna the main prey was sea birds, and of the mammals there were also hedgehogs and rats.

  1. The role of colour Doppler sonography in the diagnosis of lower limb Klippel–Trénaunay syndrome

    International Nuclear Information System (INIS)

    Qi, H.T.; Wang, X.M.; Zhang, X.D.; Zhang, M.H.; Li, C.M.; Bao, S.G.; Yuan, H.

    2013-01-01

    Aim: To investigate the accuracy of colour Doppler sonography as compared to phlebography in patients with Klippel-Trénaunay syndrome (KTS). Materials and methods: From September 2004 to May 2012, 59 consecutive patients seen in Shandong medical imaging research institute with a clinical suggestion of KTS were included. Thirty-four were female and 25 were male, with a mean age of 28.4 years. Colour Doppler sonography was used to assess the lower limb veins. The main sonographic criteria for a positive diagnosis were visualization of the lateral vein or sciatic vein, capillary haemangioma, and abnormality of the deep veins. These data were compared with phlebography findings. The κ statistic was used to determine the level of agreement. The sensitivity, specificity, positive and negative predictive values, and accuracy of colour Doppler sonography as a diagnostic test were assessed. Results: Colour Doppler sonography findings were positive in 21 of 59 patients with a clinical suggestion of KTS. The diagnosis was confirmed using phlebography in 22 patients. There were two false-positive results and one false-negative result by colour Doppler sonography. The κ-value was 0.892. Sensitivity, specificity, positive and negative predictive values, and accuracy for colour Doppler sonography were 95.4, 94.6, 91.3, 97.2, and 94.9%, respectively. Conclusion: Colour Doppler sonography is an accurate, reliable, and non-invasive investigation in the assessment of patients with suspected KTS

  2. Determination and assessment of the concentration limits to be used in SR-Can. Supplement to TR-06-32

    Energy Technology Data Exchange (ETDEWEB)

    Grive, Mireia; Domenech, Cristina; Montoya, Vanessa; Garcia, David; Duro, Lara

    2010-09-15

    This document complements and updates the report TR-06-32, Determination and assessment of the concentration limits to be used in SR-Can, in which the solubility limits of different radionuclides in the near field system and under the different scenarios selected by SKB were assessed. Since 2006, several important changes in different fields affecting solubility assessment calculations have been reported. These changes basically concern some of the thermodynamic data used in the calculations and the groundwater compositions for scenarios of interest defined by SKB. In this document we update the thermodynamic data corresponding to Ni, Zr, Th and U and we describe the thermodynamic database selected for Pb. This document also reports the update of the assessment of the concentration limits to be used in SR-Can, which has been done considering the recent thermodynamic database updates and the new groundwater compositions of interest supplied by SKB. Finally, we also present the Simple Functions spreadsheet tool, born from the need of having a confident and easy-to-handle tool to calculate solubility limits of some radionuclides under determined conditions in an agile and relatively fast manner

  3. Indústria fonográfica X novas plataformas musicais: Trânsitos sonoros na era da Internet

    Directory of Open Access Journals (Sweden)

    Tatiana Rodrigues Lima

    2011-07-01

    Full Text Available

    O artigo traz um breve panorama sobre alguns dos novos mediadores de circulação musical no século XX, pontuando os conflitos e as permanências experimentados pela indústria fonográfica no novo contexto. A participação das gravadoras nos trânsitos musicais via internet e outras plataformas digitais é confrontada com novas formas de mediação, promovidas por empresas oriundas de setores da comunicação, informática e entretenimento no comércio de arquivos, softwares e hardwares relacionados à circulação musical. Observa-se ainda que os ouvintes são cada vez mais ativos na mediação musical, através de ações nas plataformas ligadas às majors das TIs e do entretenimento, bem como da disponibilização de conteúdos (áudios, vídeos e textos em sites colaborativos e alternativos.

  4. Del tráfico a la mediación: configuración identitaria y oportunismo comunicativo

    Directory of Open Access Journals (Sweden)

    Héctor D. Fernández L'Hoeste, Ph.D.

    1999-01-01

    Full Text Available El propósito de esta ponencia es, independiente de puntos de vista enjuiciadores de la incidencia moral del fenómeno, estudiar el narcotráfico como una práctica social que, siguiendo a Martín-Barbero, sirve de mediación global. Partiendo de diversos planteamientos, del cubrimiento de los medios o de la implementación de rutas alternas de comunicación intercontinental, es factible argumentar la naturaleza propiciatoria de esta práctica en la configuración de la materialidad y expresividad del medio. Mi ponencia busca examinar cómo, a través del seguimiento de un fenómeno delincuencial, fruto de la inescrupulosidad de algunos y de la carencia de oportunidades de otros, los medios han logrado canalizar la información y situarse en el rol definitorio de identidades. En síntesis, dado su carácter protagónico, el tráfico ilegal de estupefacientes sirve de coyuntura que contribuye a la manipulación del mensaje y a la solidificación del medio en su rol interlocutor de la masa.

  5. Radiation-induced aging of PDMS Elastomer TR-55: a summary of constitutive, mesoscale, and population-based models

    Energy Technology Data Exchange (ETDEWEB)

    Maiti, A [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Weisgraber, T. H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Dinh, L. N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-11-16

    Filled and cross-linked elastomeric rubbers are versatile network materials with a multitude of applications ranging from artificial organs and biomedical devices to cushions, coatings, adhesives, interconnects, and seismic-isolation-, thermal-, and electrical barriers. External factors like mechanical stress, temperature fluctuations, or radiation are known to create chemical changes in such materials that can directly affect the molecular weight distribution (MWD) of the polymer between cross-links and alter the structural and mechanical properties. From a Materials Science point of view it is highly desirable to understand, effect, and manipulate such property changes in a controlled manner. In this report we summarize our modeling efforts on a polysiloxane elastomer TR-55, which is an important component in several of our systems, and representative of a wide class of filled rubber materials. The primary aging driver in this work has been γ-radiation, and a variety of modeling approaches have been employed, including constitutive, mesoscale, and population-based models. The work utilizes diverse experimental data, including mechanical stress-strain and compression set measurements, as well as MWD measurements using multiquantum NMR.

  6. Combined lymphangioma and hemangioma of the spleen in a patient with Klippel–Trénaunay syndrome

    Directory of Open Access Journals (Sweden)

    Spasić Marko

    2012-01-01

    Full Text Available Introduction. Klippel–Trénaunay syndrome (KTS is a very rare congenital anomaly of blood vessels, characterized by the following clinical triad: varicose superficial veins, port-wine stain and usually bony and soft tissue hypertophy of extremities, most often located in the lower extremities. It is often accompanied by visceral manifestations, and rarely combined with splenomegaly. Case Outline. A 30-year-old female patient came to the Surgery Clinic because of occasional left hypochondrial pain. After she was diagnosed with KTS combined with splenomegaly, splenectomy was performed. Macroscopic and microscopic spleen examination indicated the presence of tumor of vascular origin, presenting a combination of lymphangioma and hemangioma. Conclusion. Diagnosed KTS demands a thorough clinical examination of the patient because of the potential presence of visceral manifestations. When splenomegaly is present, even though being often benign, splenectomy is usually performed to alleviate accompanying symptoms which occur as a result of organ enlargement and compression, to prevent rupture and consequential bleeding when the vascular spleen tumor is large, and finally to avoid a possibility of malignant transformation.

  7. Identificação do lactato mínimo de corredores adolescentes em teste de pista de três estágios incrementais

    Directory of Open Access Journals (Sweden)

    Rafael da Costa Sotero

    2011-04-01

    Full Text Available OBJETIVO: Analisar a possibilidade de se determinar a velocidade de lactato mínimo (LM em corredores adolescentes utilizando-se apenas três estágios incrementais. MÉTODOS: Onze indivíduos (13,7 ± 1,0 anos; 47,3 ± 12,1kg; 160,0 ± 1,0cm; 18,3 ± 1,8kg/m² realizaram três testes de corrida em pista de atletismo em dias distintos: 1 desempenho de 3.000m (Vm3.000; 2 teste de LM que consistiu de um sprint de 500m para indução a hiperlactatemia, seguido de 10min de recuperação e seis séries de 800m em intensidades de 83, 86, 89, 92, 95 e 98% da Vm3.000; 3 teste de LM com três estágios (LMp3 semelhante ao protocolo anterior, porém, com três séries de 800m em intensidades de 83, 89 e 98% da Vm3.000. Durante o primeiro minuto de recuperação entre os estágios dos testes dois e três foram coletadas amostras de sangue para dosagem de lactato sanguíneo. Para determinação do LM foram empregadas: a inspeção visual (LM e b função polinomial de segunda ordem para identificar o LM em seis estágios (LMp e três estágios (LMp3. RESULTADOS: ANOVA demonstrou não haver diferenças entre as velocidades de lactato mínimo (m.min-1 identificadas pelos diferentes métodos (LM = 221,7 ± 15,4 vs. LMp = 227,1 ± 10,8 vs. LMp3 = 224,1 ± 11,2;. Altas correlações foram observadas entre os protocolos estudados e destes com a Vm3.000 (p < 0,01. CONCLUSÃO: Foi possível identificar a velocidade de corrida correspondente ao LM em adolescentes mesmo utilizando-se de apenas três estágios incrementais (LMp3.

  8. Tráfego veicular e mortalidade por doenças do aparelho circulatório em homens adultos

    Directory of Open Access Journals (Sweden)

    Mateus Habermann

    2012-02-01

    Full Text Available OBJETIVO: Analisar a associação entre indicadores de exposição à poluição por tráfego veicular e mortalidade por doenças do aparelho circulatório em homens adultos. MÉTODOS: Foram analisadas informações sobre vias e volume de tráfego no ano de 2007 fornecidas pela companhia de engenharia de tráfego local. Mortalidade por doenças do aparelho circulatório no ano de 2005 entre homens > 40 anos foram obtidas do registro de mortalidade do Programa de Aprimoramento de Informações de Mortalidade do Município de São Paulo, SP. Dados socioeconômicos do Censo 2000 e informações sobre a localização dos serviços de saúde também foram coletados. A exposição foi avaliada pela densidade de vias e volume de tráfego para cada distrito administrativo. Foi calculada regressão (α = 5% entre esses indicadores de exposição e as taxas de mortalidade padronizadas, ajustando os modelos para variáveis socioeconômicas, número de serviços de saúde nos distritos e autocorrelação espacial. RESULTADOS: A correlação entre densidade de vias e volume de tráfego foi modesta (r² = 0,28. Os distritos do centro apresentaram os maiores valores de densidade de vias. O modelo de regressão espacial de densidade de vias indicou associação com mortalidade por doenças do aparelho circulatório (p = 0,017. Não se observou associação no modelo de volume de tráfego. Em ambos os modelos - vias e volume de tráfego (veículos leves/pesados - a variável socioeconômica foi estatisticamente significante. CONCLUSÕES: A associação entre mortalidade por doenças do aparelho circulatório e densidade de vias converge com a literatura e encoraja a realização de mais estudos epidemiológicos em nível individual e com métodos mais acurados de avaliação da exposição.

  9. Info (TR Rao)

    Indian Academy of Sciences (India)

    ) measured in Scoville Units (SUs). Pure capsaicin: 16 M SU. Smoking Ed's Carolina reaper: 1.47 MSU. Tezpur mirchi: 0.855 MSU; 163 times the jalapeno pepper. Bhut Jolokia 1.6M; infinity chilli: 1.2M, Naga Viper: 1.4 M; Trinidad Moruga ...

  10. The truncated splice variant of peroxisome proliferator-activated receptor alpha, PPARα-tr, autonomously regulates proliferative and pro-inflammatory genes

    International Nuclear Information System (INIS)

    Thomas, Maria; Bayha, Christine; Klein, Kathrin; Müller, Simon; Weiss, Thomas S.; Schwab, Matthias; Zanger, Ulrich M.

    2015-01-01

    The peroxisome proliferator-activated receptor alpha (PPARα) controls lipid/energy homeostasis and inflammatory responses. The truncated splice variant PPARα-tr was suggested to exert a dominant negative function despite being unable to bind consensus PPARα DNA response elements. The distribution and variability factor of each PPARα variant were assessed in the well-characterized cohort of human liver samples (N = 150) on the mRNA and protein levels. Specific siRNA-mediated downregulation of each transcript as well as specific overexpression with subsequent qRT-PCR analysis of downstream genes was used for investigation of specific functional roles of PPARα-wt and PPARα-tr forms in primary human hepatocytes. Bioinformatic analyses of genome-wide liver expression profiling data suggested a possible role of PPARα-tr in downregulating proliferative and pro-inflammatory genes. Specific gene silencing of both forms in primary human hepatocytes showed that induction of metabolic PPARα-target genes by agonist WY14,643 was prevented by PPARα-wt knock-down but neither prevented nor augmented by PPARα-tr knock-down. WY14,643 treatment did not induce proliferative genes including MYC, CDK1, and PCNA, and knock-down of PPARα-wt had no effect, while PPARα-tr knock-down caused up to 3-fold induction of these genes. Similarly, induction of pro-inflammatory genes IL1B, PTGS2, and CCL2 by IL-6 was augmented by knock-down of PPARα-tr but not of PPARα-wt. In contrast to human proliferative genes, orthologous mouse genes were readily inducible by WY14,643 in PPARα-tr non-expressing AML12 mouse hepatocytes. Induction was augmented by overexpression of PPARα-wt and attenuated by overexpression of PPARα-tr. Pro-inflammatory genes including IL-1β, CCL2 and TNFα were induced by WY14,643 in mouse and human cells and both PPARα forms attenuated induction. As potential mechanism of PPARα-tr inhibitory action we suggest crosstalk with WNT/β-catenin pathway. Finally

  11. Caracterización y simulación del tráfico de redes LAN mediante el modelo MMPP

    Directory of Open Access Journals (Sweden)

    Jaime Alberto Moreno Mogollón

    2007-01-01

    Full Text Available En este artículo se presenta un método para caracterizar y simular el tráfico de acceso a Internet de cualquier red LAN con comportamiento autosimilar. Para ello se emplea el modelo de cola D-MMPP/D/1 para generar una traza discreta y analizar su comportamiento al pasar por la cola con diferentes capacidades de buffer. Este método ha sido probado por otros autores en condiciones controladas de laboratorio y solo para tráfico entrante. Nuestro estudio demuestra que esta metodología puede ser utilizada en redes LAN bajo condiciones reales y actuales tanto para tráfico autosimilar entrante como saliente. Para tal fin se utiliza el tráfico capturado en los enlaces de entrada/salida de Internet de la Red LAN de la Universidad Pontificia Bolivariana, seccional Bucaramanga. Además, esta metodología soluciona el problema de modelar tráfico autosimilar ya que genera una traza simulada aproximada a la traza medida. La exactitud del modelo se ve reflejada en la gráfica de los quantiles (Q-Q plot entre la traza medida y la traza generada mediante D-MMPP. Para realizar nuestro estudio, el modelo y los algoritmos fueron validados inicialmente utilizando trazas obtenidas en los laboratorios Bellcore. Posteriormente, se realizaron algunos ajustes para tener una traza simulada en términos de bits por segundo y no en términos de paquetes por segundo como se hace en otros trabajos, con el fin de obtener una simulación de la capacidad del canal en bits por segundo.

  12. Dieta, selectividad y solapamiento trófico entre las tallas del pez blanco Menidia humboldtiana (Atheriniformes: Atherinopsidae en el embalse Tiacaque, México

    Directory of Open Access Journals (Sweden)

    Regina Sánchez

    2013-06-01

    Full Text Available Menidia humboldtiana es una especie nativa muy apreciada por su delicado sabor. Se determinó el espectro trófico, selectividad y solapamiento trófico de ésta, durante 1995 (épocas del año, se obtuvieron muestras de zooplancton e identificaron a nivel genérico. Los peces capturados se agruparon en intervalos de longitud estándar para cada época. Se analizaron los contenidos estomacales (método volumétrico, Laevastu, selectividad (Chesson y solapamiento trófico (Morisita. Se registraron 14 géneros de zooplancton; Bosmina el más abundante (29 625ind/10L seguido por Cyclops (9 496ind/10L ambos en primavera. Los peces pequeños (1-4.9cm consumen a Cyclops en altos porcentajes en primavera e invierno, 61.24-69.82% respectivamente. Ceriodaphnia es consumida por peces de 3-10.9cm y de 13-14.9cm con 72.41-95.5% en verano; en otoño las tallas pequeñas ingieren a Mastigodiaptomus y Ceriodaphnia; Daphnia y Bosmina por peces de 5-8.9cm y los más grandes (9-14.9cm a Ceriodaphnia. M. humboldtiana realiza una depredación selectiva por Ceriodaphnia, Daphnia, Mastigodiaptomus, Bosmina y Cyclops. El solapamiento trófico fue muy marcado entre todas las tallas en primavera, otoño e invierno, a diferencia en verano los peces de 1-2.9 y 11-12.9cm no registraron un solapamiento con otros intervalos de longitud. M. humboldtiana es una especie zooplanctófaga, que realiza una depredación selectiva y un marcado solapamiento trófico entre los intervalos de longitud.

  13. Consumo abusivo de álcool e envolvimento em acidentes de trânsito na população brasileira, 2013

    Directory of Open Access Journals (Sweden)

    Giseli Nogueira Damacena

    Full Text Available Resumo O objetivo deste artigo é analisar o consumo abusivo e frequente de álcool segundo características sociodemográficas e investigar o risco de maior envolvimento em acidentes de trânsito, utilizando dados da Pesquisa Nacional de Saúde, 2013, Brasil. Eventos investigados: consumo abusivo e frequente de álcool (ingestão semanal igual ou superior de 8 doses para mulheres e 15 para homens por semana e envolvimento em acidente de trânsito com lesões corporais nos últimos 12 meses. Os dois eventos foram investigados segundo características sociodemográficas e a associação entre eles verificada por meio de regressão logística multivariada. A prevalência do consumo abusivo e frequente de álcool foi 6,1% para a população de 18 anos ou mais, sendo 8,9% entre os homens e 3,6% entre as mulheres. A prevalência de envolvimento em acidente de trânsito foi 3,1% na população geral e 6,1% entre os que referiram consumo abusivo e frequente de álcool. Após o controle por fatores sociodemográficos o consumo abusivo e frequente de álcool manteve associação estatisticamente significativa com o acidente de trânsito. Com o maior risco de envolvimento em acidentes de trânsito dentre os indivíduos que referiram consumo abusivo e frequente de álcool, monitorar a alcoolemia dos motoristas passa a ser uma possibilidade estratégica de intervenção.

  14. Comparison of Hemostasis Times With a Kaolin-Based Hemostatic Pad (QuikClot Radial) vs Mechanical Compression (TR Band) Following Transradial Access: A Pilot Prospective Study.

    Science.gov (United States)

    Roberts, Jonathan S; Niu, Jianli; Pastor-Cervantes, Juan A

    2017-10-01

    Hemostasis following transradial access (TRA) is usually achieved by mechanical compression. We investigated use of the QuikClot Radial hemostasis pad (Z-Medica) compared with the TR Band (Terumo Medical) to shorten hemostasis after TRA. Thirty patients undergoing TRA coronary angiography and/or percutaneous coronary intervention were randomized into three cohorts post TRA: 10 patients received mechanical compression with the TR Band, 10 patients received 30 min of compression with the QuikClot Radial pad, and 10 patients received 60 min of compression with the QuikClot Radial pad. Times to hemostasis and access-site complications were recorded. Radial artery patency was evaluated 1 hour after hemostasis by the reverse Barbeau's test. There were no differences in patient characteristics, mean dose of heparin (7117 ± 1054 IU), or mean activated clotting time value (210 ± 50 sec) at the end of procedure among the three groups. Successful hemostasis was achieved in 100% of patients with both the 30-min and 60-min compression groups using the QuikClot pad. Hemostasis failure occurred in 50% of patients when the TR Band was initially weaned at the protocol-driven time (40 min after sheath removal). Mean compression time for hemostasis with the TR Band was 149.4 min compared with 30.7 min and 60.9 min for the 30-min and 60-min QuikClot groups, respectively. No radial artery occlusion occurred in any subject at the end of the study. Use of the QuikClot Radial pad following TRA in this pilot trial significantly shortened hemostasis times when compared with the TR Band, with no increased complications noted.

  15. IMGT/GeneInfo: T cell receptor gamma TRG and delta TRD genes in database give access to all TR potential V(D)J recombinations

    Science.gov (United States)

    Baum, Thierry-Pascal; Hierle, Vivien; Pasqual, Nicolas; Bellahcene, Fatena; Chaume, Denys; Lefranc, Marie-Paule; Jouvin-Marche, Evelyne; Marche, Patrice Noël; Demongeot, Jacques

    2006-01-01

    Background Adaptative immune repertoire diversity in vertebrate species is generated by recombination of variable (V), diversity (D) and joining (J) genes in the immunoglobulin (IG) loci of B lymphocytes and in the T cell receptor (TR) loci of T lymphocytes. These V-J and V-D-J gene rearrangements at the DNA level involve recombination signal sequences (RSS). Whereas many data exist, they are scattered in non specialized resources with different nomenclatures (eg. flat files) and are difficult to extract. Description IMGT/GeneInfo is an online information system that provides, through a user-friendly interface, exhaustive information resulting from the complex mechanisms of T cell receptor V-J and V-D-J recombinations. T cells comprise two populations which express the αβ and γδ TR, respectively. The first version of the system dealt with the Homo sapiens and Mus musculus TRA and TRB loci whose gene rearrangements allow the synthesis of the αβ TR chains. In this paper, we present the second version of IMGT/GeneInfo where we complete the database for the Homo sapiens and Mus musculus TRG and TRD loci along with the introduction of a quality control procedure for existing and new data. We also include new functionalities to the four loci analysis, giving, to date, a very informative tool which allows to work on V(D)J genes of all TR loci in both human and mouse species. IMGT/GeneInfo provides more than 59,000 rearrangement combinations with a full gene description which is freely available at . Conclusion IMGT/GeneInfo allows all TR information sequences to be in the same spot, and are now available within two computer-mouse clicks. This is useful for biologists and bioinformaticians for the study of T lymphocyte V(D)J gene rearrangements and their applications in immune response analysis. PMID:16640788

  16. IMGT/GeneInfo: T cell receptor gamma TRG and delta TRD genes in database give access to all TR potential V(DJ recombinations

    Directory of Open Access Journals (Sweden)

    Jouvin-Marche Evelyne

    2006-04-01

    Full Text Available Abstract Background Adaptative immune repertoire diversity in vertebrate species is generated by recombination of variable (V, diversity (D and joining (J genes in the immunoglobulin (IG loci of B lymphocytes and in the T cell receptor (TR loci of T lymphocytes. These V-J and V-D-J gene rearrangements at the DNA level involve recombination signal sequences (RSS. Whereas many data exist, they are scattered in non specialized resources with different nomenclatures (eg. flat files and are difficult to extract. Description IMGT/GeneInfo is an online information system that provides, through a user-friendly interface, exhaustive information resulting from the complex mechanisms of T cell receptor V-J and V-D-J recombinations. T cells comprise two populations which express the αβ and γδ TR, respectively. The first version of the system dealt with the Homo sapiens and Mus musculus TRA and TRB loci whose gene rearrangements allow the synthesis of the αβ TR chains. In this paper, we present the second version of IMGT/GeneInfo where we complete the database for the Homo sapiens and Mus musculus TRG and TRD loci along with the introduction of a quality control procedure for existing and new data. We also include new functionalities to the four loci analysis, giving, to date, a very informative tool which allows to work on V(DJ genes of all TR loci in both human and mouse species. IMGT/GeneInfo provides more than 59,000 rearrangement combinations with a full gene description which is freely available at http://imgt.cines.fr/GeneInfo. Conclusion IMGT/GeneInfo allows all TR information sequences to be in the same spot, and are now available within two computer-mouse clicks. This is useful for biologists and bioinformaticians for the study of T lymphocyte V(DJ gene rearrangements and their applications in immune response analysis.

  17. A pouca visibilidade da mulher brasileira no tráfico de drogas La invisibilidad de la mujer brasilera ligada al tráfico de drogas The low visibility of the brazilian woman in the drug trafficking

    Directory of Open Access Journals (Sweden)

    Kátia Ovídia José de Souza

    2009-12-01

    Full Text Available Entre os estudos sobre a violência de gênero e violência conjugal, a atenção recai sobre a mulher como vítima. Sem minimizar a importância desta questão, com base em uma discussão teórica com autores da área da saúde e da sociologia em saúde da década de 2000, este artigo tem como objetivo investigar a violência feminina. A literatura sobre violência de gênero tem poucas referências sobre a visibilidade da mulher como autora de atos de violência, especificamente o tráfico de drogas, o principal motivo do aprisionamento de mulheres nos últimos anos, o qual contribui para o aumento dos índices da mulher como autora de atos de violência. Deste modo, este artigo tenta contribuir com o conhecimento sobre a temática violência feminina, tema pouco estudado.Entre los estudios sobre violencia de género y violencia conyugal, la atención recae sobre la mujer como víctima. Sin restar importancia a esta cuestión, con base en la discusión teórica basada en autores del área de la salud y de la sociología de la salud en la década de 2000, este artículo tiene como objetivo investigar la violencia femenina. En la literatura sobre violencia de género se encuentran escasas referencias sobre la visibilidad de la mujer como autora de actos violentos, específicamente, como participante en el tráfico de drogas; aún siendo este el principal motivo de prisión entre mujeres en los últimos años, y un hecho que sin duda contribuye al aumento de los índices de la mujer como autora de actos de violencia. Así, este artículo se propone a contribuir al conocimiento sobre la violencia femenina, tema escasamente trabajado.Between the studies about gender and marital violence, the focus is more on women as victims of violence. This situation is important, but based on a theoretical discussion with authors of the health and sociology health field during the decade 2000, this article aims to investigate the feminine violence. In the

  18. Le semis très précoce : une stratégie agronomique pour améliorer les performances du soja en France ?

    Directory of Open Access Journals (Sweden)

    Maury Pierre

    2015-09-01

    Full Text Available Le semis très précoce du soja a été étudié dans l’objectif d’améliorer le potentiel de rendement et/ou de réduire les besoins en eau. Trois variétés, appartenant à différents groupes de maturité, ont été retenues afin d’identifier les traits variétaux d’intérêt pour le semis très précoce. Un ensemble d’essais multilocaux, comportant deux modalités de semis avec irrigation, a été réalisé au cours de 5 années culturales (2010−2014. Le rendement et les besoins en eau ont été déterminés; un suivi dynamique du développement et de la croissance a été réalisé pour la variété Santana. Les effets combinés des basses températures et de la photopériode en réponse au semis précoce se traduisent par une production de biomasse aérienne réduite en phase végétative et une augmentation de la durée de remplissage des graines. Les valeurs maximales de rendement sont observées pour le semis très précoce, mais en moyenne le rendement est sensiblement plus faible en semis très précoce (3,7 t/ha vs. 3,9 t/ha. L’irrigation pour conduire les cultures dans des conditions proches de l’ETM a été sensiblement plus faible en semis très précoce (170 mm vs. 182 mm. Une variété tardive (groupe de maturité II apparaît mieux adaptée au semis très précoce qu’une variété de groupe de maturité I. Cette étude constitue une première référence agronomique d’évaluation du semis très précoce du soja et suggère que des types variétaux très tardifs pourraient améliorer le potentiel de rendement du soja en semis très précoce pour des conduites irriguées dans le Sud-Ouest de la France.

  19. Trafficking in persons: a health concern? Tráfico de pessoas: uma preocupação da Saúde?

    Directory of Open Access Journals (Sweden)

    Cathy Zimmerman

    2009-08-01

    Full Text Available Human trafficking is a phenomenon that has now been documented in most regions in the world. Although trafficking of women and girls for sexual exploitation is the most commonly recognised form of trafficking, it is widely acknowledged that human trafficking also involves men, women and children who are trafficked for various forms of labour exploitation and into other abusive circumstances. Despite the violence and harm inherent in most trafficking situations, there remains extremely little evidence on the individual and public health implications of any form of human trafficking. The Brazilian government has recently launched a national plan to combat human trafficking. However, because the health risks associated with human trafficking have not been well-recognised or documented, there is extremely limited reliable data on the health needs of trafficked persons to inform policy and practices.. Brazilian policy-makers and service providers should be encouraged to learn about the likely range of health impacts of trafficking, and incorporate this into anti-trafficking protection and response strategies. As well as prevention activities, the government, international and local organisations should work together with the public health research community to study the health needs of trafficked persons and explore opportunities to provide safe and appropriate services to victims in need of care.O tráfico de pessoas é um fenômeno que foi registrado na maioria das regiões do mundo. Embora o tráfico de mulheres e meninas para exploração sexual seja a forma mais comumente reconhecida de tráfico, sabe-se que o comércio ilegal de pessoas envolve também homens, mulheres e crianças, em várias formas de exploração de trabalho e circunstâncias abusivas. Apesar da violência e danos inerentes à maioria das situações de tráfico, há ainda muito pouca evidência sobre as implicações do tráfico de pessoas para a saúde individual e p

  20. Factors related to non-recovery from whiplash. The Nord-Trøndelag Health Study (HUNT).

    Science.gov (United States)

    Myrtveit, Solbjørg Makalani; Skogen, Jens Christoffer; Petrie, Keith J; Wilhelmsen, Ingvard; Wenzel, Hanne Gro; Sivertsen, Børge

    2014-06-01

    Whiplash injuries show a variable prognosis which is difficult to predict. Most individuals experiencing whiplash injuries rapidly recover but a significant proportion develop chronic symptoms and ongoing disability. By employing longitudinal data, we investigated how psychological and physical symptoms, self-rated health, use of health services and medications, health behavior and demographic factors predict recovery from whiplash. Data from two waves of a large, Norwegian, population-based study (The Nord-Trøndelag Health Study: HUNT2 and HUNT3) were used. Individuals reporting whiplash in HUNT2 (baseline) were identified in HUNT3 11 years later. The characteristics of individuals still suffering from whiplash in HUNT3 were compared with the characteristics of individuals who had recovered using Pearson's chi-squared test, independent sample t-tests and logistic regression. At follow-up, 31.6 % of those reporting whiplash at baseline had not recovered. These individuals (n = 199) reported worse health at baseline than recovered individuals (n = 431); they reported poorer self-rated health (odds ratio [OR] = 3.12; 95 % confidence interval [CI], 2.20-4.43), more symptoms of anxiety (OR = 1.70; 95 % CI, 1.15-2.50), more diffuse somatic symptoms (OR = 2.38; 95 % CI, 1.61-3.51) and more musculoskeletal symptoms (OR = 1.21; 95 % CI, 1.13-1.29). Individuals still suffering from whiplash also visited more health practitioners at baseline (OR = 1.18; 95 % CI, 1.06-1.32) and used more medications (OR = 1.24; 95 % CI, 1.09-1.40). Poor self-rated health seems to be a strong risk factor for whiplash injuries becoming chronic. Diffuse somatic symptoms, musculoskeletal symptoms and symptoms of anxiety at baseline are important prognostic risk factors. Knowledge of these maintaining risk factors enables identification of individuals at risk of non-recovery, facilitating adequate treatment for this vulnerable group.

  1. Halophilic mechanism of the enzymatic function of a moderately halophilic dihydrofolate reductase from Haloarcula japonica strain TR-1.

    Science.gov (United States)

    Miyashita, Yurina; Ohmae, Eiji; Ikura, Teikichi; Nakasone, Kaoru; Katayanagi, Katsuo

    2017-05-01

    Dihydrofolate (DHF) reductase coded by a plasmid of the extremely halophilic archaeon Haloarcula japonica strain TR-1 (HjDHFR P1) shows moderate halophilicity on enzymatic activity at pH 6.0, although there is no significant effect of NaCl on its secondary structure. To elucidate the salt-activation and -inactivation mechanisms of this enzyme, we investigated the effects of pH and salt concentration, deuterium isotope effect, steady-state kinetics, and rapid-phase ligand-binding kinetics. Enzyme activity was increased eightfold by the addition of 500 mM NaCl at pH 6.0, fourfold by 250 mM at pH 8.0, and became independent of salt concentration at pH 10.0. Full isotope effects observed at pH 10.0 under 0-1000 mM NaCl indicated that the rate of hydride transfer, which was the rate-determining step at the basic pH region, was independent of salt concentration. Conversely, rapid-phase ligand-binding experiments showed that the amplitude of the DHF-binding reaction increased and the tetrahydrofolate (THF)-releasing rate decreased with increasing NaCl concentration. These results suggested that the salt-activation mechanism of HjDHFR P1 is via the population change of the anion-unbound and anion-bound conformers, which are binding-incompetent and -competent conformations for DHF, respectively, while that of salt inactivation is via deceleration of the THF-releasing rate, which is the rate-determining step at the neutral pH region.

  2. DSM-IV-TR “pain disorder associated with psychological factors” as a nonhysterical form of somatization

    Science.gov (United States)

    Aragona, Massimiliano; Tarsitani, Lorenzo; De Nitto, Serena; Inghilleri, Maurizio

    2008-01-01

    BACKGROUND: Elevated Minnesota Multiphasic Personality Inventory (MMPI) scores on the hysteria (Hy) scale are reported in several forms of pain. Previous results were possibly biased by diagnostic heterogeneity (psychogenic, somatic and mixed pain syndromes included in the same index sample) or Hy heterogeneity (failure to differentiate Hy scores into clinically meaningful sub-scales, such as admission of symptoms [Ad] and denial of symptoms [Dn]). METHODS: To overcome this drawback, 48 patients diagnosed as having a Diagnostic and Statistical Manual of Mental Disorders, 4th edn, Text Revision (DSM-IV-TR) diagnosis of “pain disorder associated with psychological factors” were compared with 48 patients experiencing somatic pain excluding psychological factors, and 42 somatic controls without pain. RESULTS: MMPI Hy and hypochondriasis (Hs) scores were significantly higher in the pain disorder group than in control groups, who scored similarly. MMPI correction (K) scores and Dn scores were similar in the three groups, whereas Ad was significantly higher in the pain disorder group and lower and similar in the two control groups, respectively. In the pain disorder group, Ad and Dn were negatively correlated, whereas in control groups they were unrelated. CONCLUSIONS: These findings suggest that whereas a pattern of high Hs and Hy scores together with a normal K score might characterize patients with a pain disorder associated with psychological factors, elevated Hy scores per se do not indicate hysterical traits. In the pain disorder group, elevated Hy scores reflected the Ad subscale alone, indicating a strikingly high frequency of distressing somatic symptoms. They tend not to repress or deny the emotional malaise linked to symptoms, as the hysterical construct expects. The pain disorder designation should be considered a nonhysterical form of somatization. PMID:18301811

  3. Feo-hifomicose subcutânea no Estado do Pará: relato de três casos

    Directory of Open Access Journals (Sweden)

    Maria Vanda Catão Arnaud

    1996-06-01

    Full Text Available São descritos três casos de feo-hifomicose subcutânea, os primeiros encontrados no Estado do Pará, todos oriundos de localidades situadas a leste de Belém, nas micron-regiões do Salgado e Bragantina. O diagnóstico teve por base o reconhecimento dos parasitos em cortes histológicos, sem identificação de espécie, uma vez que todo o material disponível para exame - compreendendo as lesões completamente excisadas -, ao ser recebido, já estava fixado em formol e imprestável, portanto, para qualquer tentativa de estudo micológico. A abmidância de elementos fúngicos verificada nos tecidos, após impregnação pela prata (métodos de Grocott e de Fontana-Masson, contrastava com a dificuldade para visualizá-los em cortes não-corados ou corados por hematoxilina-eosina, fato devido certamente ao aspecto das hifas neles existentes: delgadas, de paredes finas e cor quase imperceptível.Three cases of subcutaneous phaeohyphomycosis from the State of Para, Brazil, are reported. This is the first time that this form of phaeohyphomycosis is described in Northern Brazil. The etiologic agents could not be isolated, and the diagnosis in all cases was stablished only on histopathological basis, particularly through the demonstration of fungal elements in tissue sections. Hyphal fragments and vesicidar cells were very numerous and conspicuous in special (Grocott and Fontana-Masson methods stained sections, in contrast to their apparent scarcity in routine hematoxilin-eosin preparations. The difference was certainly due to the aspect in the latter of the invasive tissue forms: the thin-walled and light brown pigmented organisms stained poorly and were veiy difficult to distinguish from the tissue components.

  4. Non-genomic effects of the NR4A1/Nur77/TR3/NGFIB orphan nuclear receptor.

    Science.gov (United States)

    Pawlak, Alicja; Strzadala, Leon; Kalas, Wojciech

    2015-03-01

    The orphan nuclear receptor NR4A1/Nur77/TR3/NGFIB acts primarily as a transcription factor to regulate the expression of multiple genes. However, increasing research attention has recently been given to non-genomic activities of NR4A1. The first description of a non-genomic action of NR4A1 referred to the conversion of anti-apoptotic Bcl-2 into a pro-apoptotic protein by direct interaction with NR4A1. In response to certain apoptotic stimuli, NR4A1 translocates from the nucleus to the mitochondrial outer membrane (MOM) where it associates with Bcl-2 and thereby causes apoptosis. Afterwards, it appeared that NR4A1 could also bind and convert other anti-apoptotic Bcl-2 family members. The latest studies indicate a significant role of NR4A1 in the process of autophagy. For example, a new NR4A1-mediated pathway specific for melanoma cells has been described where NR4A1 interacts with the adenine nucleotide translocase 1 (ANT1) on the mitochondrial inner membrane (MIM) leading to induction of the autophagy pathway. Moreover, NR4A1 interaction with cytoplasmic p53 may also contribute to the induction of autophagy. In addition to mitochondria, NR4A1 could be translocated to the outer membrane of the endoplasmic reticulum (ER) and associate with Bcl-2 or translocon-associated protein subunit γ (TRAPγ) causing ER stress-induced apoptosis. NR4A1 also contributes to the proteasomal degradation of β-catenin in colon cancer cells in vitro and in vivo, as well as to the stabilization of hypoxia-inducible factor-1α (HIF-1α) under non-hypoxic conditions. This review summarizes research findings on non-genomic effects of NR4A1 in normal and cancer cells. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Empujados hacia la muerte. Guiones trágicos para los hombres que aman a otros hombres.

    Directory of Open Access Journals (Sweden)

    Miguel Arroyo Fernández

    2011-07-01

    Full Text Available Pensadores como Michel Foucault,  Judith Butler o Ricardo Llamas, han llamado la atención acerca de la estrecha relación que se establece en la cultura occidental entre la homosexualidad y la muerte, lo cual se manifiesta en sus creaciones culturales. Otro rasgo que caracteriza la politica sexual predominante es la desvirtuación de la bisexualidad originaria del ser humano, a través del establecimiento de dos categorías excluyentes: homosexual y heterosexual. Con objeto de verificar cómo todo ello se refleja en nuestros discursos cinematográficos se ha escogido un corpus amplio de películas  europeas y norteamericanas, de todas las épocas, que incluyen en su relato un evento específico: el de la muerte de uno o varios personajes que mantienen relaciones sexuales con personas de su mismo sexo. Se han detectado varias líneas narrativas que se repiten, de las cuales se han incluido aquí ejemplos de las siguientes: la perplejidad el hombre ante su propia ambivalencia sexual y su trágico destino cuando infringe la norma heterosexista; la muerte social, el suicidio y las conductas autodestructivas; la ejecución del sodomita; el asesinato del homosexual como resultado del clima de homofobia, la muerte del homosexual malvado; la eliminación del intruso en la relación heterosexual. Se concluye que, efectivamente, el cine es un agente activo en la difusión de narrativas que asocian estrechamente la homosexualidad con la muerte.

  6. Un nuevo caso de pseudotumor inflamatorio de la tráquea A new case of inflammatory tracheal tumor

    Directory of Open Access Journals (Sweden)

    Edelberto Fuentes Valdés

    2008-12-01

    Full Text Available El pseudotumor inflamatorio de tráquea es poco frecuente y puede simular un tumor cuando se localiza en la luz traqueal o bronquial. El objetivo del presente artículo fue presentar un nuevo caso y revisar la literatura especializada. Se trató de una paciente de 23 años de edad, con cuadro de disnea de varios años de evolución, tratada con el diagnóstico de asma bronquial. Fue intervenida de urgencia por empeoramiento de la disnea y diagnóstico de tumor intratraqueal, según estudio broncoscópico. Se practicó la resección de 5 anillos traqueales con anastomosis término-terminal. La evolución posoperatoria fue satisfactoria y la paciente se encuentra libre de recidiva 5 años después de la operación.The inflammatory tracheal pseudotumor is rare and it may mimic a tumor when it is located in the tracheal or bronchial light. The objective of this article was to present a new case and to review the specialized literature. The case of a 23-year-old patient with a picture of dyspnea of several years of evolution treated with diagnosis of bronchial asthma was reported. She underwent emergency surgery due the worsening of dypsnea and to the diagnosis of intratracheal tumor according to a bronchoscopic study. The resection of 5 tracheal rings was performed with termino-terminal anastomosis. The postoperative evolution was satisfactory and the patient has been free of relapse five years after the operation.

  7. Excesso de velocidade no trânsito: análise sob a perspectiva da moralida

    Directory of Open Access Journals (Sweden)

    Gislei Mocelin Polli

    Full Text Available Este trabalho focaliza o desenvolvimento moral como um dos fatores relacionados ao comportamento inadequado no trânsito. O objetivo foi estudar a relação entre o nível de desenvolvimento moral e o comportamento infrator dos motoristas, partindo da hipótese que a infração estaria relacionada com os primeiros estágios de desenvolvimento moral propostos por Kohlberg. Para esta pesquisa, foram analisadas entrevistas qualitativas com 20 motoristas com mais de nove multas por excesso de velocidade, das quais 49 respostas foram selecionadas, já que as demais não possibilitavam análise do nível de desenvolvimento moral. O estudo permitiu verificar que o estágio 1 de desenvolvimento moral predomina em 75,51% das respostas dos motoristas infratores entrevistados. A característica principal desse estágio é a preocupação com a punição, expressa na resposta “eu não sabia que ali tinha radar”. Essa resposta indica que, se não houvesse fiscalização e, em consequência, punição, não haveria motivo para não infringir a lei. Este estudo indica limitações na aplicação da teoria de desenvolvimento moral baseada nas justificativas, pois estas se aplicam a ações infratoras ou não. Além disso, o estudo não focalizou dilemas e privilegiou a análise das respostas, portanto, o estágio 1 foi característico de respostas, e não de sujeitos.

  8. Excesso de velocidade no trânsito: análise sob a perspectiva da moralidade

    Directory of Open Access Journals (Sweden)

    Gislei Mocelin Polli

    Full Text Available Este trabalho focaliza o desenvolvimento moral como um dos fatores relacionados ao comportamento inadequado no trânsito. O objetivo foi estudar a relação entre o nível de desenvolvimento moral e o comportamento infrator dos motoristas, partindo da hipótese que a infração estaria relacionada com os primeiros estágios de desenvolvimento moral propostos por Kohlberg. Para esta pesquisa, foram analisadas entrevistas qualitativas com 20 motoristas com mais de nove multas por excesso de velocidade, das quais 49 respostas foram selecionadas, já que as demais não possibilitavam análise do nível de desenvolvimento moral. O estudo permitiu verificar que o estágio 1 de desenvolvimento moral predomina em 75,51% das respostas dos motoristas infratores entrevistados. A característica principal desse estágio é a preocupação com a punição, expressa na resposta “eu não sabia que ali tinha radar”. Essa resposta indica que, se não houvesse fiscalização e, em consequência, punição, não haveria motivo para não infringir a lei. Este estudo indica limitações na aplicação da teoria de desenvolvimento moral baseada nas justificativas, pois estas se aplicam a ações infratoras ou não. Além disso, o estudo não focalizou dilemas e privilegiou a análise das respostas, portanto, o estágio 1 foi característico de respostas, e não de sujeitos.

  9. Tráfego veicular e mortalidade por doenças do aparelho circulatório em homens adultos Tráfico vehicular y mortalidad por enfermedades del aparato circulatorio en hombres Motor vehicle traffic and cardiovascular mortality in male adults

    OpenAIRE

    Mateus Habermann; Nelson Gouveia

    2012-01-01

    OBJETIVO: Analisar a associação entre indicadores de exposição à poluição por tráfego veicular e mortalidade por doenças do aparelho circulatório em homens adultos. MÉTODOS: Foram analisadas informações sobre vias e volume de tráfego no ano de 2007 fornecidas pela companhia de engenharia de tráfego local. Mortalidade por doenças do aparelho circulatório no ano de 2005 entre homens > 40 anos foram obtidas do registro de mortalidade do Programa de Aprimoramento de Informações de Mortalidade do ...

  10. Investigation of Two Outbreaks of Gastroenteritis in Tržič in September 2011 / Preiskava Dveh Izbruhov Gastroenteritisa V Tržiču V Septembru 2011

    Directory of Open Access Journals (Sweden)

    Krt Lah Andreja

    2015-03-01

    Full Text Available Uvod. Izbruh gastroenteritisa neopredeljene etiologije in izbruh salmoneloze sta bila hkrati v Tržiču septembra 2011. Namen preiskave izbruhov je bil odkriti izvor in poti prenosa okužbe s ciljem, da se sprejmejo ukrepi za prekinitev širjenja. Metode. V dveh retrospektivnih študijah primerov in kontrol je bila z univariatnimi in multivariatnimi analizami testirana povezava med gastroenteritisom neopredeljene etiologije oziroma salmonelozo in uživanjem hrane v gostilni ali pitjem vodovodne vode. Primer v prvi študiji je bil oboleli s salmonelozo, primer v drugi študiji pa je bil vsak občan z drisko in/ali bruhanjem. Primere obolelih so prijavili zdravniki; kontrole so bile izbrane med zdravimi osebami, ki so vrnile izpolnjeni vprašalnik. Rezultati. Osebe, izpostavljene hrani v gostilni, so imele 24,8-krat višje obete za obolevanje za salmonelozo kot neizpostavljeni (univariatna analiza RO 24,8; 95 % IZ 7,5-82,3; p < 0,05; multivariatna analiza RO 14,7; 95% IZ 3,5-61,3, p < 0,05. Občani, ki so pili vodo iz določenega vodnega vira, so imeli 3,4-krat višje obete, da so oboleli za gastroenteritisom neopredeljene etiologije kot neizpostavljeni (univariatna analiza RO 3,4; 95 % IZ je 2,2-5,1; p < 0,05; multivariatni analizi RO 2,9; 95 % IZ 1,7-5,3; p < 0,05. Statistično značilna je bila tudi povezava med obolevanjem in količino popite pitne vode. Zaključki. Z analitičnima študijama primerov in kontrol smo potrdili vzročno povezanost med salmonelozo in prehranjevanjem v določeni gostilni ter povezanost med gastroenteritisom neopredeljene etiologije in pitjem vodovodne vode iz določenega vodnega vira. Mogoč je vnos Salmonelle enteritidis v gostilno prek vodovodne vode

  11. Variations iconographiques : Constantin le Grand dans les peintures des églises de Pătrăuţi et d’Arbore / Iconographic Variations: Constantine the Great in the Paintings of the Churches of Pătrăuţi and Arbore

    OpenAIRE

    Tereza Sinigalia

    2014-01-01

    Iconographic Variations: Constantine the Great in the Paintings of the Churches of Pătrăuţi and Arbore. The article, written in 2013, the Constantinian Year, takes back and develops some ideas which can be found in my previous articles concerning the murals in both of churches in discussion. „The Exaltation of the Holy Cross” of the former nun’s monastery Pătrăuţi and the church dedicated to „The Beheading of St John the Baptist” in the village Arbore. The first is the foundation of the Molda...

  12. Papel ecológico en la cadena trófica de los peces que pasan el invierno en ecosistema de la laguna Culbin Sands, NE Escocia: Identificación de las principales interacciones tróficas y comprovación de los efectos del pez Pomatoschistus microps (Pall

    OpenAIRE

    Mariyam Mendonça, Vanda; Raffaelli, David; Boyle, Peter; Emes, Chas

    2007-01-01

    Se estudió el ecosistema de la laguna Culbin Sands, NE Escocia, durante un periodo de tres años (1994-1996) con objeto de identificar los principales acoplamientos tróficos desde invertebrados bentónicos a depredadores epibentónicos, y para evaluar el impacto de los peces que pasan el invierno sobre las comunidades de sus presas. Cada 2-4 semanas, la fauna móvil se muestreó para estudiar su dieta. Las principales interacciones tróficas identificadas, entre invertebrados bentóncos y depredador...

  13. Edema agudo hemorrágico da infância: relato de três casos Acute hemorrhagic edema of infancy: report of three cases

    OpenAIRE

    Paulo Sergio Emerich; Patricia Almeida Prebianchi; Luciene Lage da Motta; Elton Almeida Lucas; Leonardo Mello Ferreira

    2011-01-01

    O Edema Agudo Hemorrágico da Infância é uma vasculite leucocitoclástica pouco frequente, que ocorre, quase exclusivamente, em crianças entre 4 meses e 2 anos de idade. Caracteriza-se, clinicamente, pela tríade febre, lesões purpúricas na face, pavilhões auriculares e extremidades e edema. Embora os achados cutâneos sejam dramáticos e de surgimento rápido, o prognóstico é favorável, com resolução espontânea dentro de 1 a 3 semanas. Descrevem-se três casos cujos achados clínicos e histopatológi...

  14. Inventarios viales y categorización de la red vial en estudios de Ingeniería de Tránsito y Transporte

    Directory of Open Access Journals (Sweden)

    Julián Rodrigo Quintero

    2011-03-01

    Full Text Available Se presentan las principales consideraciones y los aspectos técnicos fundamentales de la elaboración de Inventarios Viales y la Categorización de la Red Vial, aplicadas a la realización de estudios de ingeniería de tránsito y transporte. Se exponen los aspectos generales relacionados con la elaboración de los inventarios de infraestructura vial, de señalización y dispositivos de control, de estacionamientos, de paraderos y de rutas de transporte público colectivo urbano de pasajeros, como una herramienta práctica para complementar los procedimientos de campo y optimizar los procesos y análisis de resultados orientados a identificar, caracterizar y cuantificar las variables relacionadas con el desarrollo del fenómeno del tránsito y la actividad del transporte.

  15. Actividad asistencial de las unidades de soporte vital avanzado a accidentes de tráfico en Asturias en el año 2010

    OpenAIRE

    Villar Fernández, Lara

    2012-01-01

    Se realizó un estudio observacional retrospectivo de los accidentes de tráfico y atropellos asistidos por las USVA del 1 de enero al 31 de diciembre del 2010, utilizando el ASTER y complementando con una revisión de las historias clínicas en papel. Se analizaron 596 accidentes de tráfico, de los 1821 registrados por la DGT en el año 2010 en Asturias, en los que se asistieron a 782 pacientes, con una edad media de 39,4 años (∂ = 19,8) el 62,5% fueron hombres y 37,4% mujeres. Hubo 26 fallecidos...

  16. Tríplice fronteira Brasil, Peru e Colômbia e as implicações com o narcotráfico

    OpenAIRE

    Dias Balieiro, Luiz Felipe de Vasconcelos; Nascimento, Izaura Rodrigues

    2015-01-01

    Na região do Alto Solimões, extremo oeste do Amazonas, localiza-se a chamada Tríplice Fronteira Amazônica, formada pelas cidades de Tabatinga/Brasil, Santa Rosa/Peru e Letícia/Colômbia. Esta zona fronteiriça é identificada como uma das portas de entrada dos entorpecentes oriundos das zonas produtoras do Peru e Colômbia no território brasileiro. Este artigo objetiva promover a análise das características do narcotráfico na tríplice fronteira amazônica, com uma breve exposição do seu processo d...

  17. Entre a Identidade e a Máscara: um Estudo de “Três Máscaras” de José Régio

    OpenAIRE

    Madeira D'Ascensão, Maria

    2013-01-01

    "Três Máscaras” é uma peça de teatro da autoria de José Régio. Nesta, conforme o próprio título o sugere, sobressaem três personagens que sustentam disfarces num baile de máscaras. Na verdade, estas estão mascaradas das emblemáticas personagens Columbina, Pierrot e Mefistófeles que  à semelhança do que sucedia nas encenações da Commedia dell’arte em que se visava uma criação coletiva sujeita à inspiração do momento  fantasiam um diálogo e uma ação norteados pelo simbolismo do respetivo disf...

  18. BINARY CENTRAL STARS OF PLANETARY NEBULAE DISCOVERED THROUGH PHOTOMETRIC VARIABILITY. IV. THE CENTRAL STARS OF HaTr 4 AND Hf 2-2

    Energy Technology Data Exchange (ETDEWEB)

    Hillwig, Todd C.; Schaub, S. C. [Department of Physics and Astronomy, Valparaiso University, Valparaiso, IN 46383 (United States); Bond, Howard E. [Department of Astronomy and Astrophysics, Pennsylvania State University, University Park, PA 16802 (United States); Frew, David J. [Department of Physics, The University of Hong Kong, Pokfulam Road (Hong Kong); Bodman, Eva H. L., E-mail: todd.hillwig@valpo.edu [Southeastern Association for Research in Astronomy (SARA) (United States)

    2016-08-01

    We explore the photometrically variable central stars of the planetary nebulae HaTr 4 and Hf 2-2. Both have been classified as close binary star systems previously based on their light curves alone. Here, we present additional arguments and data confirming the identification of both as close binaries with an irradiated cool companion to the hot central star. We include updated light curves, orbital periods, and preliminary binary modeling for both systems. We also identify for the first time the central star of HaTr 4 as an eclipsing binary. Neither system has been well studied in the past, but we utilize the small amount of existing data to limit possible binary parameters, including system inclination. These parameters are then compared to nebular parameters to further our knowledge of the relationship between binary central stars of planetary nebulae and nebular shaping and ejection.

  19. Hábitos alimentarios e interacciones tróficas de Anisotremus interruptus (Pisces: Haemulidae y Lutjanus argentiventris (Pisces: Lutjanidae en el Pacífico Central Mexicano

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    Juan R Flores-Ortega

    2014-03-01

    Full Text Available Se obtuvieron estómagos de ejemplares adultos de Anisotremus interruptus y Lutjanus argentiventris para conocer los componentes alimentarios de cada especie y sus interacciones tróficas durante un periodo de surgencia en el Pacífico Central Mexicano. Se identificaron 79 tipos de presas agrupadas en 15 categorías alimentarias. La dieta de A. interruptus está constituida principalmente de microinvertebrados (anfípodos y larvas de crustáceos, holotúridos y ofiuros. L. argentiventris se alimenta de macroinvertebrados (camarones, cangrejos y estomatópodos, peces y cefalópodos. Ambas especies presentan una estrategia alimentaria generalista y una superposición trófica baja. La dieta de estas especies está relacionada con la apertura de la boca.

  20. The Relationship Between the Childhood Autism Rating Scale: Second Edition and Clinical Diagnosis Utilizing the DSM-IV-TR and the DSM-5.

    Science.gov (United States)

    Dawkins, Tamara; Meyer, Allison T; Van Bourgondien, Mary E

    2016-10-01

    The Childhood Autism Rating Scale, Second Edition (CARS2; 2010) includes two rating scales; the CARS2-Standard Version (CARS2-ST) and the newly developed CARS2-High Functioning Version (CARS2-HF). To assess the diagnostic agreement between the CARS2 and DSM-IV-TR versus DSM-5 criteria for Autism Spectrum Disorder (ASD), clinicians at community based centers of the University of North Carolina TEACCH Autism Program rated participants seen for a diagnostic evaluation on symptoms of autism using both the DSM-IV-TR and DSM-5 criteria and either the CARS2-HF or the CARS2-ST. Findings suggest that overall, the diagnostic agreement of the CARS2 remains high across DSM-IV and DSM-5 criteria for autism.