WorldWideScience

Sample records for tr xanh trn

  1. TrnL-trnF intergenetic spacer and trnL intron define major clades within Luzula and Juncus (Juncaceae): Importance of structural mutations

    Czech Academy of Sciences Publication Activity Database

    Drábková, Lenka; Kirschner, Jan; Vlček, Čestmír; Pačes, Václav

    2004-01-01

    Roč. 59, - (2004), s. 1-10 ISSN 0022-2844 R&D Projects: GA AV ČR KSK6005114; GA ČR GA206/02/0355; GA MŠk(CZ) LN00A079 Institutional research plan: CEZ:AV0Z6005908 Keywords : Luzula * Juncus * trnL-trnF Subject RIV: EF - Botanics Impact factor: 2.751, year: 2004

  2. Phylogenetic relationships in Solanaceae and related species based on cpDNA sequence from plastid trnE-trnT region

    Directory of Open Access Journals (Sweden)

    Danila Montewka Melotto-Passarin

    2008-01-01

    Full Text Available Intergenic spacers of chloroplast DNA (cpDNA are very useful in phylogenetic and population genetic studiesof plant species, to study their potential integration in phylogenetic analysis. The non-coding trnE-trnT intergenic spacer ofcpDNA was analyzed to assess the nucleotide sequence polymorphism of 16 Solanaceae species and to estimate its ability tocontribute to the resolution of phylogenetic studies of this group. Multiple alignments of DNA sequences of trnE-trnT intergenicspacer made the identification of nucleotide variability in this region possible and the phylogeny was estimated by maximumparsimony and rooted with Convolvulaceae Ipomoea batatas, the most closely related family. Besides, this intergenic spacerwas tested for the phylogenetic ability to differentiate taxonomic levels. For this purpose, species from four other families wereanalyzed and compared with Solanaceae species. Results confirmed polymorphism in the trnE-trnT region at different taxonomiclevels.

  3. Taxonomy, phylogenetics and biogeography of Chesneya (Fabaceae), evidenced from data of three sequences, ITS, trnS-trnG, and rbcL

    Science.gov (United States)

    Ming-Li Zhang; Zhi-Bin Wen; Xiao-Li Hao; Vyacheslav V. Byalt; Alexander P. Sukhorukov; Stewart C. Sanderson

    2015-01-01

    Plants of Central Asia have played a significant role in the origin of floras of Eurasia and the Northern Hemisphere. Chesneya, a small leguminous genus occurring in Central Asia, western Asia, and Tibet, is used to establish phylogenetic relationships and discuss the evolutionary and biogeographical history based on sequence data of ITS and trnS-trnG and rbcL.We...

  4. Classification and differentiation of the genus Peganum indigenous to China based on chloroplast trnL-F and psbA-trnH sequences and seed coat morphology.

    Science.gov (United States)

    Zhao, T; Wang, Z-T; Branford-White, C J; Xu, H; Wang, C-H

    2011-11-01

    The genus Peganum (Zygophyllaceae) consists of six species and one subspecies; three of which are distributed in China, P. harmala Linn, P. nigellastrum Bunge and P. multisectum (Maxim.) Bobr. A probable new or intermediate species, Peganum sp., has been suggested in the wild in northwest China. Traditional classification in genus Peganum has focused on hairs on the plant surface. In this study, seed coat characteristics of Peganum species were investigated using light and scanning electron microscopy, demonstrating clear differences in morphology between species. In addition, DNA sequence data from two sequences (chloroplast: trnL-F, psbA-trnH) were used to differentiate Peganum sp. and study polygenetic relationships. Diversity in DNA sequences among Peganum species was found, with inter-specific sequence divergence ranging from 0.6% to 5.6% in psbA-trnH, and 0.0% to 1.8% in trnL-F. The variations within species were low: from 0.0% to 0.4% in psbA-trnH and 0.0% to 0.4% in trnL-F. Therefore, Peganum species can now be easily identified as separate entities based on variations in DNA sequences. Phylogenetic trees were constructed from the combined data set for the two gene fragments, and the results indicate that Peganum sp. is monophyletic and sister to P. harmala and P. nigellastrum, while P. multisectum is also monophyletic. DNA data further confirmed that P. multisectum is an independent species and that a new species, Peganum sp., exists within the genus Peganum growing wild in China. © 2011 German Botanical Society and The Royal Botanical Society of the Netherlands.

  5. TrnH-psbA sequence analyses of asparagus cochinchinensis from different geographical origin in China

    Directory of Open Access Journals (Sweden)

    Ma Yingzi

    2017-01-01

    Full Text Available This template explains and demonstrates how to prepare your camera-ready paper for The trnH-psbA sequences of 13 Asparagus cochinchinensis populations from 6 provinces of China were studied. The results showed that length of trnH-psbA change and the mutation of GC content were small. The length of trnH-psbA sequences were from 619 bp to 632 bp, and the GC content was about 36%. The total variation rates of 13 populations were from 2.21% to 3.47%, when the missing sites were considered as variation sites. A. cochinchinensis from different sources had 10 information sites in trnH-psbA sequence, accounting for 1.58% of the total sequence. The information sites were located in the sites 8, 9, 120, 457, 458, 486, 487, 491, 492, and 593, respectively. Clustering analysis showed that the Qianxi and Hengshan populations clustered together; Dushan, Yuqing, and Guangzhou populations were grouped; Nanning and Xinning populations formed another cluster. trnH-psbA sequences could identify different A. cochinchinensis populations. Clustering of different A. cochinchinensis populations related primarily to latitude and had little relationship with longitude.

  6. Træfacader

    DEFF Research Database (Denmark)

    Johansen, Bjarne Lund

    Håndbogen er den første samlede anvisning om træfacader fra Træinformaiton. Bogen vejleder om træbeklædningers opbygning og beskyttelse mod vejrliget, samt om gældende materialekrav og udvalgte træarters egnethed. Bogen behandler de mest anvendte former for bræddebeklædninger både til træskelethu...

  7. The mitochondrial genome of the Russian wheat aphid Diuraphis noxia: large repetitive sequences between trnE and trnF in aphids.

    Science.gov (United States)

    Zhang, Bo; Ma, Chuan; Edwards, Owain; Fuller, Susan; Kang, Le

    2014-01-01

    To characterize aphid mitochondrial genome (mitogenome) features, we sequenced the complete mitogenome of the Russian wheat aphid, Diuraphis noxia. The 15,784-bp mitogenome with a high A+T content (84.76%) and strong C skew (-0.26) was arranged in the same gene order as that of the ancestral insect. Unlike typical insect mitogenomes, D. noxia possessed a large tandem repeat region (644 bp) located between trnE and trnF. Sequencing partial mitogenome of the cotton aphid (Aphis gossypii) further confirmed the presence of the large repeat region in aphids, but with different repeat length and copy number. Another motif (58 bp) tandemly repeated 2.3 times in the control region of D. noxia. All repeat units in D. noxia could be folded into stem-loop secondary structures, which could further promote an increase in copy numbers. Characterization of the D. noxia mitogenome revealed distinct mitogenome architectures, thus advancing our understanding of insect mitogenomic diversities and evolution. © 2013 Elsevier B.V. All rights reserved.

  8. Trækonstruktioner

    DEFF Research Database (Denmark)

    Larsen, H.J.; Riberholt, H.

    Denne anvisning behandler materialer til trækonstruktioner og beregning af sædvanlige elementer og konstruktioner i henhold til Trænormen fra 2003 med tillæg. Forbindelser behandles i SBI-anvisning 194: Trækonstruktioner. Forbindelser. Anvisningen er tænkt anvendt af projekterende og som lærebog på...

  9. Patterns of nucleotide substitution in angiosperm cpDNA trnL (UAA)-F(GAA) regions

    NARCIS (Netherlands)

    Bakker, F.T.; Culham, A.; Gomez-Martinez, R.; Carvalho, J.; Compton, J.; Dawtrey, R.; Gibby, M.

    2000-01-01

    Patterns of substitution in chloroplast encoded trnL-F regions were compared between species of Actaea (Ranunculales), Digitalis (Scrophulariales), Drosera (Caryophyllales), Panicoideae (Poales), the small chromosome species clade of Pelargonium (Geraniales), each representing a different order of

  10. Phylogenetic inferences of Nepenthes species in Peninsular Malaysia revealed by chloroplast (trnL intron) and nuclear (ITS) DNA sequences

    OpenAIRE

    Bunawan, Hamidun; Yen, Choong Chee; Yaakop, Salmah; Noor, Normah Mohd

    2017-01-01

    Background The chloroplastic trnL intron and the nuclear internal transcribed spacer (ITS) region were sequenced for 11 Nepenthes species recorded in Peninsular Malaysia to examine their phylogenetic relationship and to evaluate the usage of trnL intron and ITS sequences for phylogenetic reconstruction of this genus. Results Phylogeny reconstruction was carried out using neighbor-joining, maximum parsimony and Bayesian analyses. All the trees revealed two major clusters, a lowland group consi...

  11. The Analysis of Pandanus Relationship of Purwodadi Botanical Garden Collections Based on Morphological Character and Molecular Marker (trnL and trnL-F

    Directory of Open Access Journals (Sweden)

    Risca Adiyani Rachma

    2017-10-01

    Full Text Available The morphological characteristics of plant vegetative organ has the potential to be the defining factor of pandanus family collection at Purwodadi Botanical Garden (PBG. However, the information is not enough to confirm the identity of pandanus at the type-level. This problem happened at the collection of PBG. It is an urgent issue considering PBG as one of the most important ex-situ plant conservation institute that also has function as a study source for plant taxonomy science in Indonesia. Therefore, the use of molecular technology analysis using molecular marker (primer is incredibly important to identify the member of pandanus family by identifying its family relationship pattern. This information was expected to give a clarity about the identity of Pandanus family at PBG which will support further research and activity for pandanus conservation. The plant sample includes 16 specimens of pandanus with one member of the family from Freycinetia as the outgroup. Morphological analysis of the 50 characteristics of vegetative organs (leaf, stem, and root was conducted. Molecular analysis of DNA using primer of trnL and trnL-F. The data sequence as a result of the analysis was then tested using homology test with BLAST. All of the DNA sequence was paralleled using Clustal W analysis, the tree construction relationship was analysed using Maximum Parsimony (MP method with MEGA 6.0 program. The results of morphological studies showed the character vegetative that is the position of the spines on the leaves, the shape of apex leaf and the condition of the root surface above the soil. Molecularly, appears 1 new genera that has not been previously identified by PBG researcher is Benstonea.

  12. The architecture of the chloroplast trnH-psbA non-coding region in angiosperms

    Czech Academy of Sciences Publication Activity Database

    Štorchová, Helena; Olson, M.S.

    2007-01-01

    Roč. 268, 1-4 (2007), s. 235-256 ISSN 0378-2697 R&D Projects: GA MŠk(CZ) LC06004 Grant - others:ESPSCor Visiting Scholar Research Grant(US) NSF DEB 0317115 Institutional research plan: CEZ:AV0Z50380511 Source of funding: V - iné verejné zdroje ; V - iné verejné zdroje Keywords : Chloroplast DNA * psbA-trnH intergenic region * Silene * deletions * insertions and inversions in stem-loop region * psbA 3´untranslated region * RNA secondary structure Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 1.492, year: 2007

  13. Unique haplotypes of cacao trees as revealed by trnH-psbA chloroplast DNA

    Directory of Open Access Journals (Sweden)

    Nidia Gutiérrez-López

    2016-04-01

    Full Text Available Cacao trees have been cultivated in Mesoamerica for at least 4,000 years. In this study, we analyzed sequence variation in the chloroplast DNA trnH-psbA intergenic spacer from 28 cacao trees from different farms in the Soconusco region in southern Mexico. Genetic relationships were established by two analysis approaches based on geographic origin (five populations and genetic origin (based on a previous study. We identified six polymorphic sites, including five insertion/deletion (indels types and one transversion. The overall nucleotide diversity was low for both approaches (geographic = 0.0032 and genetic = 0.0038. Conversely, we obtained moderate to high haplotype diversity (0.66 and 0.80 with 10 and 12 haplotypes, respectively. The common haplotype (H1 for both networks included cacao trees from all geographic locations (geographic approach and four genetic groups (genetic approach. This common haplotype (ancient derived a set of intermediate haplotypes and singletons interconnected by one or two mutational steps, which suggested directional selection and event purification from the expansion of narrow populations. Cacao trees from Soconusco region were grouped into one cluster without any evidence of subclustering based on AMOVA (FST = 0 and SAMOVA (FST = 0.04393 results. One population (Mazatán showed a high haplotype frequency; thus, this population could be considered an important reservoir of genetic material. The indels located in the trnH-psbA intergenic spacer of cacao trees could be useful as markers for the development of DNA barcoding.

  14. Efficiency of matK, rbcL, trnH-psbA, and trnL-F (cpDNA) to Molecularly Authenticate Philippine Ethnomedicinal Apocynaceae Through DNA Barcoding.

    Science.gov (United States)

    Cabelin, Vincent Louie Domingo; Alejandro, Grecebio Jonathan Duran

    2016-05-01

    The Philippines is home to some ethnomedicinal Apocynaceae that has been used to cure common ailments. They are perceived to be safe, but misidentification can lead to substitution and adulteration. Morphological characters are primarily utilized to identify these species but a new method utilizing molecular characters called DNA barcoding has emerged. In this study, the efficiency of matK, rbcL, trnH-psbA, and trnL-F to molecularly authenticate selected Apocynaceae species were tested. Genomic DNA from silica-dried leaf samples were isolated and used as a template for generating DNA barcodes. Pair-wise sequence divergence using Kimura-2-Parameter was used to analyze inter-specific and intraspecific variations among the barcodes, whereas basic local alignment search tool (BLAST) and neighbor-joining (NJ) analyses were employed to examine discrimination success. The results show that matK is the best barcode for Apocynaceae as it has the highest amplification and sequencing success together with rbcL while having high inter-specific and low intra-specific divergence relative to the other candidate barcodes. Furthermore, matK provided the highest discrimination both in BLAST and NJ analyses. This study proposes the use of matK as the principal barcode for Apocynaceae. Both matK and rbcL have higher universality compared to trnH-psbA and trnL-F matK has relatively high inter-specific divergence and very minimal intra-specific divergencematK is the best barcode to molecularly authenticate Apocynaceae with either trnH-psbA or trnL-F as supplements. Abbreviations used: K2P: Kimura-2-parameter, BLAST: Basic local alignment search tool, NJ: Neighbor-joining.

  15. Phylogenetic inferences of Nepenthes species in Peninsular Malaysia revealed by chloroplast (trnL intron) and nuclear (ITS) DNA sequences.

    Science.gov (United States)

    Bunawan, Hamidun; Yen, Choong Chee; Yaakop, Salmah; Noor, Normah Mohd

    2017-01-26

    The chloroplastic trnL intron and the nuclear internal transcribed spacer (ITS) region were sequenced for 11 Nepenthes species recorded in Peninsular Malaysia to examine their phylogenetic relationship and to evaluate the usage of trnL intron and ITS sequences for phylogenetic reconstruction of this genus. Phylogeny reconstruction was carried out using neighbor-joining, maximum parsimony and Bayesian analyses. All the trees revealed two major clusters, a lowland group consisting of N. ampullaria, N. mirabilis, N. gracilis and N. rafflesiana, and another containing both intermediately distributed species (N. albomarginata and N. benstonei) and four highland species (N. sanguinea, N. macfarlanei, N. ramispina and N. alba). The trnL intron and ITS sequences proved to provide phylogenetic informative characters for deriving a phylogeny of Nepenthes species in Peninsular Malaysia. To our knowledge, this is the first molecular phylogenetic study of Nepenthes species occurring along an altitudinal gradient in Peninsular Malaysia.

  16. Ancient paralogy in the cpDNA trnL-F region in Annonaceae: implications for plant molecular systematics

    NARCIS (Netherlands)

    Pirie, M.D.; Vargas, M.P.B.; Botermans, M.; Bakker, F.T.; Chatrou, L.W.

    2007-01-01

    The plastid trnL-F region has proved useful in molecular phylogenetic studies addressing diverse evolutionary questions from biogeographic history to character evolution in a broad range of plant groups. An important assumption for phylogenetic reconstruction is that data used in combined analyses

  17. [Reconstruction of the phylogenetic position of larch (Larix sukaczewii Dylis) by sequencing data for the trnK intron of chloroplast DNA].

    Science.gov (United States)

    Bashalkhanov, S I; Konstantinov, Iu M; Verbitskiĭ, D S; Kobzev, V F

    2003-10-01

    To reconstruct the systematic relationships of larch Larix sukaczewii, we used the chloroplast trnK intron sequences of L. decidua, L. sukaczewii, L. sibirica, L. czekanovskii, and L. gmelinii. Analysis of phylogenetic trees constructed using the maximum parsimony and maximum likelihood methods showed a clear divergence of the trnK intron sequences between L. sukaczewii and L. sibirica. This divergence reaches intraspecific level, which supports a previously published hypothesis on the taxonomic isolation of L. sukaczewii.

  18. Fugtsikre træfacader

    DEFF Research Database (Denmark)

    Hansen, Morten Hjorslev; Nicolajsen, Asta

    Denne rapport dokumenterer, at det stadig vil være muligt at udføre fugtsikre træfacader, hvis isoleringskravene øges svarende til ca. 300 mm mineraluld. Fugtophobningen i en række træfacadeelementer med forskellige konstruktionsopbygninger, isoleringsmaterialer og -tykkelser er bestemt. Målinger...

  19. Chloroplast phylogeny of asplenioid ferns based on rbcL and trnL-F Spacer sequences (Polypodiidae, aspleniaceae) and its implications for biogeography

    NARCIS (Netherlands)

    Schneider, H.; Russell, S.J.; Cox, C.J.; Bakker, F.T.; Henderson, S.; Rumsey, F.; Barrett, J.; Gibby, M.; Vogel, J.C.

    2004-01-01

    Molecular phylogenies have been generated to investigate relationships among species and putative segregates in Asplenium, one of the largest genera in ferns. Of the ~700 described taxa, 71 are included in a phylogenetic analysis using the chloroplast rbcL gene and trnL-F spacer. Our results support

  20. Use of rbcL and trnL-F as a two-locus DNA barcode for identification of NW-European ferns: an ecological perspective.

    Directory of Open Access Journals (Sweden)

    G Arjen de Groot

    2011-01-01

    Full Text Available Although consensus has now been reached on a general two-locus DNA barcode for land plants, the selected combination of markers (rbcL + matK is not applicable for ferns at the moment. Yet especially for ferns, DNA barcoding is potentially of great value since fern gametophytes--while playing an essential role in fern colonization and reproduction--generally lack the morphological complexity for morphology-based identification and have therefore been underappreciated in ecological studies. We evaluated the potential of a combination of rbcL with a noncoding plastid marker, trnL-F, to obtain DNA-identifications for fern species. A regional approach was adopted, by creating a reference database of trusted rbcL and trnL-F sequences for the wild-occurring homosporous ferns of NW-Europe. A combination of parsimony analyses and distance-based analyses was performed to evaluate the discriminatory power of the two-region barcode. DNA was successfully extracted from 86 tiny fern gametophytes and was used as a test case for the performance of DNA-based identification. Primer universality proved high for both markers. Based on the combined rbcL + trnL-F dataset, all genera as well as all species with non-equal chloroplast genomes formed their own well supported monophyletic clade, indicating a high discriminatory power. Interspecific distances were larger than intraspecific distances for all tested taxa. Identification tests on gametophytes showed a comparable result. All test samples could be identified to genus level, species identification was well possible unless they belonged to a pair of Dryopteris species with completely identical chloroplast genomes. Our results suggest a high potential of the combined use of rbcL and trnL-F as a two-locus cpDNA barcode for identification of fern species. A regional approach may be preferred for ecological tests. We here offer such a ready-to-use barcoding approach for ferns, which opens the way for answering a

  1. Fleretagers træhuse - Brandforhold

    DEFF Research Database (Denmark)

    Dragsted, Anders; Markert, Frank; Larsen, Finn

    2017-01-01

    Dette notat er udarbejdet som del af InnoBYG spireprojektet: Fleretagers Træhuse i Danmark – Er det muligt og hvad mangler? Det overordnede mål med projektet er, at skabe et langsigtet fundament for større anvendelse af træ i fleretagers byggeri i Danmark og gøre træ til et mere naturligt valg fo...

  2. Friluftsinstallationer i træer

    DEFF Research Database (Denmark)

    Skov, Simon; Thomsen, Iben Margrete

    2015-01-01

    Abebaner, treetop walking, high rope adventure, slackline, træhuse og parkour-baner er alle installationer, som bruger træerne som støtte, enten midlertidigt eller permanent. Den nye sport, turistattraktionen eller team building-redskabet sætter i alle tilfælde træerne på prøve. Der følger positiv...

  3. Assessment of the food habits of the Moroccan dorcas gazelle in M'Sabih Talaa, west central Morocco, using the trnL approach.

    Directory of Open Access Journals (Sweden)

    Moulay Abdeljalil Ait Baamrane

    Full Text Available Food habits of the Moroccan dorcas gazelle, Gazella dorcas massaesyla, previously investigated in the 1980s using microhistological fecal analysis, in the M'Sabih Talaa Reserve, west central Morocco, were re-evaluated over three seasons (spring, summer and autumn 2009 using the trnL approach to determine the diet composition and its seasonal variation from fecal samples. Taxonomic identification was carried out using the identification originating from the database built from EMBL and the list of plant species within the reserve. The total taxonomic richness in the reserve was 130 instead of 171 species in the 1980s. The diet composition revealed to be much more diversified (71 plant taxa belonging to 57 genus and 29 families than it was 22 years ago (29 identified taxa. Thirty-four taxa were newly identified in the diet while 13 reported in 1986-87 were not found. Moroccan dorcas gazelle showed a high preference to Acacia gummifera, Anagallis arvensis, Glebionis coronaria, Cladanthus arabicus, Diplotaxis tenuisiliqua, Erodium salzmannii, Limonium thouini, Lotus arenarius and Zizyphus lotus. Seasonal variations occurred in both number (40-41 taxa in spring-summer and 49 taxa in autumn vs. respectively 23-22 and 26 in 1986-1987 and taxonomic type of eaten plant taxa. This dietary diversification could be attributed either to the difference in methods of analysis, trnL approach having a higher taxonomic resolution, or a potential change in nutritional quality of plants over time.

  4. Phylogenetic analysis of the genus Avena based on chloroplast intergenic spacer psbA-trnH and single-copy nuclear gene Acc1.

    Science.gov (United States)

    Yan, Hong-Hai; Baum, Bernard R; Zhou, Ping-Ping; Zhao, Jun; Wei, Yu-Ming; Ren, Chang-Zhong; Xiong, Fang-Qiu; Liu, Gang; Zhong, Lin; Zhao, Gang; Peng, Yuan-Ying

    2014-05-01

    Two uncorrelated nucleotide sequences, chloroplast intergenic spacer psbA-trnH and acetyl CoA carboxylase gene (Acc1), were used to perform phylogenetic analyses in 75 accessions of the genus Avena, representing 13 diploids, seven tetraploid, and four hexaploids by maximum parsimony and Bayesian inference. Phylogenic analyses based on the chloroplast intergenic spacer psbA-trnH confirmed that the A genome diploid might be the maternal donor of species of the genus Avena. Two haplotypes of the Acc1 gene region were obtained from the AB genome tetraploids, indicating an allopolyploid origin for the tetraploid species. Among the AB genome species, both gene trees revealed differences between Avena agadiriana and the other species, suggesting that an AS genome diploid might be the A genome donor and the other genome diploid donor might be the Ac genome diploid Avena canariensis or the Ad genome diploid Avena damascena. Three haplotypes of the Acc1 gene have been detected among the ACD genome hexaploid species. The haplotype that seems to represent the D genome clustered with the tetraploid species Avena murphyi and Avena maroccana, which supported the CD genomic designation instead of AC for A. murphyi and A. maroccana.

  5. Assessment of the Food Habits of the Moroccan Dorcas Gazelle in M’Sabih Talaa, West Central Morocco, Using the trnL Approach

    Science.gov (United States)

    Ait Baamrane, Moulay Abdeljalil; Shehzad, Wasim; Ouhammou, Ahmed; Abbad, Abdelaziz; Naimi, Mohamed; Coissac, Eric; Taberlet, Pierre; Znari, Mohammed

    2012-01-01

    Food habits of the Moroccan dorcas gazelle, Gazella dorcas massaesyla, previously investigated in the 1980s using microhistological fecal analysis, in the M’Sabih Talaa Reserve, west central Morocco, were re-evaluated over three seasons (spring, summer and autumn 2009) using the trnL approach to determine the diet composition and its seasonal variation from fecal samples. Taxonomic identification was carried out using the identification originating from the database built from EMBL and the list of plant species within the reserve. The total taxonomic richness in the reserve was 130 instead of 171 species in the 1980s. The diet composition revealed to be much more diversified (71 plant taxa belonging to 57 genus and 29 families) than it was 22 years ago (29 identified taxa). Thirty-four taxa were newly identified in the diet while 13 reported in 1986–87 were not found. Moroccan dorcas gazelle showed a high preference to Acacia gummifera, Anagallis arvensis, Glebionis coronaria, Cladanthus arabicus, Diplotaxis tenuisiliqua, Erodium salzmannii, Limonium thouini, Lotus arenarius and Zizyphus lotus. Seasonal variations occurred in both number (40–41 taxa in spring-summer and 49 taxa in autumn vs. respectively 23–22 and 26 in 1986–1987) and taxonomic type of eaten plant taxa. This dietary diversification could be attributed either to the difference in methods of analysis, trnL approach having a higher taxonomic resolution, or a potential change in nutritional quality of plants over time. PMID:22558187

  6. Assessment of the food habits of the Moroccan dorcas gazelle in M'Sabih Talaa, west central Morocco, using the trnL approach.

    Science.gov (United States)

    Ait Baamrane, Moulay Abdeljalil; Shehzad, Wasim; Ouhammou, Ahmed; Abbad, Abdelaziz; Naimi, Mohamed; Coissac, Eric; Taberlet, Pierre; Znari, Mohammed

    2012-01-01

    Food habits of the Moroccan dorcas gazelle, Gazella dorcas massaesyla, previously investigated in the 1980s using microhistological fecal analysis, in the M'Sabih Talaa Reserve, west central Morocco, were re-evaluated over three seasons (spring, summer and autumn 2009) using the trnL approach to determine the diet composition and its seasonal variation from fecal samples. Taxonomic identification was carried out using the identification originating from the database built from EMBL and the list of plant species within the reserve. The total taxonomic richness in the reserve was 130 instead of 171 species in the 1980s. The diet composition revealed to be much more diversified (71 plant taxa belonging to 57 genus and 29 families) than it was 22 years ago (29 identified taxa). Thirty-four taxa were newly identified in the diet while 13 reported in 1986-87 were not found. Moroccan dorcas gazelle showed a high preference to Acacia gummifera, Anagallis arvensis, Glebionis coronaria, Cladanthus arabicus, Diplotaxis tenuisiliqua, Erodium salzmannii, Limonium thouini, Lotus arenarius and Zizyphus lotus. Seasonal variations occurred in both number (40-41 taxa in spring-summer and 49 taxa in autumn vs. respectively 23-22 and 26 in 1986-1987) and taxonomic type of eaten plant taxa. This dietary diversification could be attributed either to the difference in methods of analysis, trnL approach having a higher taxonomic resolution, or a potential change in nutritional quality of plants over time.

  7. Molecular genotyping of Trapa bispinosa and T. japonica (Trapaceae) based on nuclear AP2 and chloroplast DNA trnL-F region.

    Science.gov (United States)

    Kim, Changkyun; Ryun Na, Hye; Choi, Hong-Keun

    2010-12-01

    • Two marker systems were developed for the molecular identification of three Trapa species based on the length variation of nuclear AP2 and trnL-F chloroplast intergenic spacer region. • Our marker systems analyzed 118 individuals among 36 populations from three Trapa species. Trapa incisa was found to have a unique genotype from the other two species. Individuals of T. bispinosa were distinguished from T. japonica because the former had only a single AP2 genotype. Moreover, our results suggest a hybrid status of T. japonica in terms of two bands within an individual. One band was specific to T. japonica and the other one shared with T. bispinosa. • Our marker system demonstrates that nucleotide sequence variations can serve as a fast, reliable, and reproducible tool for molecular genotyping and examining the natural hybrid of water chestnut species.

  8. Landbrugets trædemølle

    DEFF Research Database (Denmark)

    Hansen, Henning Otte

    2016-01-01

    Teorien om landbrugets trædemølle siger, at teknologi medfører stigende produktivitet, stigende udbud og dermed faldende priser. Dermed øges behovet for ny teknologi. Det vedvarende teknologipres gavner de innovative landmænd, mens de mere afventende landmænd kun oplever de negative virkninger i...... form af prisfald. I denne artikel beskrives nærmere de enkelte elementer i trædemøllen. Samtidig vurderes trædemøllens betydning og mulige påvirkning. Det konkluderes, at trædemøllen, dens forudsætninger og afledte virkninger stadig er fuldt gældende. Det er ikke muligt for et enkelt land eller region...... af bremse trædemøllen på lang sigt. På lokalt plan kan man løse nogle sociale og økonomiske problemer skabt af trædemøllen gennem nemmere afvandring....

  9. Plastid trnF pseudogenes are present in Jaltomata, the sister genus of Solanum (Solanaceae): molecular evolution of tandemly repeated structural mutations.

    Science.gov (United States)

    Poczai, Péter; Hyvönen, Jaakko

    2013-11-01

    Extensive gene duplication arranged in a tandem array is rare in the plastome of embryophytes. Interestingly, we found pseudogene copies of the trnF gene in the genus Jaltomata, the sister genus of Solanum where such gene duplication has been previously reported. In each Jaltomata sequence available we found two pseudogene copies in close 5'-proximity to the original functional gene. The size of each pseudogene copy ranged between 17 and 48 bp and the anticodon domain was identified as the most conserved element. A common ATT(G)n motif is particularly interesting and its modifications were found to border the 3' of the duplicated regions. Other motifs were partial residues, or entire parts of the T- and D-domains, and both domains proved to be variable in length among the pseudogenes identified. The residues of the 3' and 5' acceptor stem were not found among the copies. We further compared the newly discovered copies of Jaltomata with those ones previously described from Solanum and inferred phylogenetic relationships of the copies aligned. The evolution of Solanum copies, in contrast to Jaltomata, is hard to explain as resulting only in parsimonious changes since reticulate evolutionary patterns were detected among the copies. The dynamic evolutionary patterns of Solanum might be explained by possible inter- or intrachromosomal recombination. © 2013 Elsevier B.V. All rights reserved.

  10. Assessing Molecular Signature for Some Potential Date (Phoenix dactylifera L. Cultivars from Saudi Arabia, Based on Chloroplast DNA Sequences rpoB and psbA-trnH

    Directory of Open Access Journals (Sweden)

    M. Ashraf

    2011-10-01

    Full Text Available Phoenix dactylifera L. (date palm, being economically very important, is widely cultivated in the Middle East and North Africa, having about 400 different cultivars. Assessment of date cultivars under trading and farming is a widely accepted problem owing to lack of a unique molecular signature for specific date cultivars. In the present study, eight different cultivars of dates viz., Khodry, Khalas, Ruthana, Sukkari, Sefri, Segae, Ajwa and Hilali were sequenced for rpoB and psbA-trnH genes and analyzed using bioinformatics tools to establish a cultivar-specific molecular signature. The combined aligned data matrix was of 1147 characters, of which invariable and variable sites were found to be 958 and 173, respectively. The analysis clearly reveals three major groups of these cultivars: (i Khodary, Sefri, Ajwa, Ruthana and Hilali (58% BS; (ii Sukkari and Khalas (64% BS; and (iii Segae. The economically most important cultivar Ajwa showed similarity with Khodary and Sefri (67% BS.The sequences of the date cultivars generated in the present study showed bootstrap values between 38% and 70% so these sequences could be carefully used as molecular signature for potential date cultivars under trading and selection of genuine cultivars at the seedling stage for farming.

  11. Assessing Molecular Signature for Some Potential Date (Phoenix dactylifera L.) Cultivars from Saudi Arabia, Based on Chloroplast DNA Sequences rpoB and psbA-trnH

    Science.gov (United States)

    Al-Qurainy, Fahad; Khan, Salim; Al-Hemaid, Fahad M.; Ali, M. Ajmal; Tarroum, M.; Ashraf, M.

    2011-01-01

    Phoenix dactylifera L. (date palm), being economically very important, is widely cultivated in the Middle East and North Africa, having about 400 different cultivars. Assessment of date cultivars under trading and farming is a widely accepted problem owing to lack of a unique molecular signature for specific date cultivars. In the present study, eight different cultivars of dates viz., Khodry, Khalas, Ruthana, Sukkari, Sefri, Segae, Ajwa and Hilali were sequenced for rpoB and psbA-trnH genes and analyzed using bioinformatics tools to establish a cultivar-specific molecular signature. The combined aligned data matrix was of 1147 characters, of which invariable and variable sites were found to be 958 and 173, respectively. The analysis clearly reveals three major groups of these cultivars: (i) Khodary, Sefri, Ajwa, Ruthana and Hilali (58% BS); (ii) Sukkari and Khalas (64% BS); and (iii) Segae. The economically most important cultivar Ajwa showed similarity with Khodary and Sefri (67% BS).The sequences of the date cultivars generated in the present study showed bootstrap values between 38% and 70% so these sequences could be carefully used as molecular signature for potential date cultivars under trading and selection of genuine cultivars at the seedling stage for farming. PMID:22072924

  12. Blog.tr.ee ei anna alla / Raigo Neudorf

    Index Scriptorium Estoniae

    Neudorf, Raigo

    2007-01-01

    Veebikeskkonna blog.tr.ee arengust ja majandamisest räägivad keskkonna looja Andris Reinmann ja firma OÜ Tr.ee osaniku Mobi Solutions'i esindaja Rain Rannu. Vt. samas: Mis on blog.tr.ee; Kaljundi: blog.tr.ee on hobiprojekt. Kommenteerib nagi.ee juhataja Jüri Kaljundi. Lisatud joonis: Blog.tr.ee unikaalsete külastajate arv nädalas

  13. The LWS TR&T Program

    Science.gov (United States)

    Sibeck, D.

    NASA's Living With a Star (LWS) Targetted Research and Technology (TR&T) program focuses on space science research areas with the potential for societal impact, e.g. forecasting variations in the solar EUV radiation and corresponding ionospheric effects, coronal mass ejections and corresponding geomagnetic and auroral activity, ionospheric radio propagation, variations in radiation belt particle intensity, and the influence of space weather upon the Earth's climate. Examples of LWS-funded research projects in each area will be given. With the guidance of an initial Science Definition Team and an ongoing Steering Committee with rotating membership, the TR&T program will set research objectives, encourage cross-disciplinary research and end-to-end modeling efforts, and define the metrics needed to evaluate these efforts. The program will provide a publically-accessible WWW site to host tools and data sets developed by the program, and may institute a series of workshops.

  14. Neuroblastomicose: registro de três casos

    Directory of Open Access Journals (Sweden)

    Ehrenfried O. Wittig

    1968-03-01

    Full Text Available São relatados três casos de neuroblastomicose de sintomatologia variada (urna forma tumoral cerebelar, urna forma abscedante troncular e cerebral e urna forma granulomatosa difusa. No caso da forma tumoral cerebelar havia associação com cisticercose cerebral. Alterações medulares não foram evidenciadas no único caso em que foi possível examinar êste setor do sistema nervoso central (caso 2.

  15. trné elektrárny jako nový sociální fenomén

    Czech Academy of Sciences Publication Activity Database

    Frantál, Bohumil

    2007-01-01

    Roč. 13, č. 11 (2007), s. 19-20 ISSN 1211-0507. [Vítr a energie větru. Lesná, Vranov nad Dyjí, 09.10.2007-10.10.2007] Institutional research plan: CEZ:AV0Z30860518 Keywords : wind turbines * perception * public opinion * surveys * NIMBY syndrom * place marketing Subject RIV: AO - Sociology, Demography

  16. 3rd MeTrApp Conference

    CERN Document Server

    Lovasz, Erwin-Christian; Hüsing, Mathias

    2015-01-01

    This volume deals with topics such as mechanism and machine design, biomechanics and medical engineering, gears, mechanical transmissions, mechatronics, computational and experimental methods, dynamics of mechanisms and machines, micromechanisms and microactuators, and history of mechanisms and transmissions. Following MeTrApp 2011 and 2013, held under the auspices of the IFToMM, these proceedings of the 3rd Conference on Mechanisms, Transmissions and Applications offer a platform for original research presentations for researchers, scientists, industry experts and students in the fields of mechanisms and transmissions with special emphasis on industrial applications in order to stimulate the exchange of new and innovative ideas.

  17. In vivo recognition of cyclopentadienyltricarbonylrhenium (CpTR) derivatives

    Energy Technology Data Exchange (ETDEWEB)

    Uehara, Tomoya; Koike, Miho; Nakata, Hideo; Miyamoto, Shigehiko; Motoishi, Shoji; Hashimoto, Kazuyuki; Oku, Naoto; Nakayama, Morio; Arano, Yasushi E-mail: arano@p.chiba-u.ac.jp

    2003-04-01

    In vivo metabolism of [{sup 188}Re]tricarbonyl(carboxycyclopentadienyl)rhenium ([{sup 188}Re]CpTR-COOH) and its glycine conjugate ([{sup 188}Re]CpTR-Gly) was investigated to estimate the applicability of cyclopentadienyltricarbonylrhenium (CpTR) compounds to {sup 186/188}Re-labeling reagents for polypeptides and peptides. Both [{sup 188}Re]CpTR derivatives were stable after incubation in a buffered-solution and in murine plasma at 37 deg. C for 6 h. Plasma protein binding was hardly observed with the two derivatives. However, different biodistribution and metabolic fates were observed with the two CpTR derivatives. While more lipophilic [{sup 188}Re]CpTR-COOH was excreted by both hepatobiliary and urinary excretion, the majority of less lipophilic [{sup 188}Re]CpTR-Gly was excreted by urinary excretion. In addition, while [{sup 188}Re]CpTR-Gly was rapidly excreted into urine as its intact structure, [{sup 188}Re]CpTR-COOH was metabolized to more hydrophilic compounds including its glycine conjugate, [{sup 188}Re]CpTR-Gly. Renal excretion of [{sup 188}Re]CpTR-Gly was significantly reduced in probenecid retreated mice. The present studies reinforced that CpTR core remained stable under biological environment. CpTR-COOH was partially recognized as an aromatic acid and was metabolized as such. However, glycine conjugation rendered CpTR-COOH hydrophilic enough to be excreted into urine without further metabolism. These findings suggested that radiolabeling reagents that liberate [{sup 186/188}Re]CpTR-Gly from covalently conjugated {sup 186/188}Re-labeled polypeptides and peptides by the action of renal brush border enzymes would be useful to reduce renal radioactivity levels.

  18. Trækonstruktioner + Tillæg 1, 2005

    DEFF Research Database (Denmark)

    Larsen, H.J.; Riberholt, H.

    Denne anvisning behandler beregning og udførelse af forbindelser i trækonstruktioner i henhold til de normer for bygningskonstruktioner, der udkom i 1998. Materialer generelt og beregning af sædvanlige elementer og konstruktioner er behandlet i SBI-anvisning 193 Trækonstruktioner, Beregning. Anvi...

  19. Aasta trükise 2000 võitjad selgunud

    Index Scriptorium Estoniae

    2000-01-01

    Rahvusvaheline žürii valis välja 6 raamatut, reklaam- ja väiketrükist ning etiketiseeria. Parimad trükised, trükikojad, kujundajad. Publikuauhinna võitsid üliõpilased Terje Homutov, Monika Eensalu, Tim Kolk

  20. BUSINNES MODEL OF CORS-TR (TUSAGA-AKTIF

    Directory of Open Access Journals (Sweden)

    S. Bakici

    2017-11-01

    Full Text Available CORS-TR (TUSAGA-Aktif (Turkish National Permanent GNSS Network – Active, serves location information at cm level accuracy in Turkey and TR Northern Cyprus in few seconds, where adequate numbers of GNSS satellites are observed and communication possibilities are present. No ground control points and benchmarks are necessary. There are 146 permanent GNSS stations within the CORS-TR System. Station data are transferred online to the main control center located in the Mapping Department of the General Directorate of Land Registry and Cadastre. CORS-TR System was established in 2008 and has been updated in software, hardware, communication and pricing areas from technical and administrative point of view in order to improve the system and provide better service to the users. Thus, the added value obtained from the CORS-TR System has been increased and contributed to the more efficient use of country resources. In this paper, how the technical, administrative and financial studies in the operation of the CORS-TR System were managed with a sustainable business model, studies for solving problems encountered in operating of the system, the cost / benefit analysis of the system and the sharing of experience gained from the perspective of how web-based applications are managed and the business model of the CORS-TR System are explained in detail.

  1. Businnes Model of Cors-Tr Tusaga-Aktif

    Science.gov (United States)

    Bakici, S.; Erkek, B.; İlbey, A.; Kulaksiz, E.

    2017-11-01

    CORS-TR (TUSAGA-Aktif (Turkish National Permanent GNSS Network - Active)), serves location information at cm level accuracy in Turkey and TR Northern Cyprus in few seconds, where adequate numbers of GNSS satellites are observed and communication possibilities are present. No ground control points and benchmarks are necessary. There are 146 permanent GNSS stations within the CORS-TR System. Station data are transferred online to the main control center located in the Mapping Department of the General Directorate of Land Registry and Cadastre. CORS-TR System was established in 2008 and has been updated in software, hardware, communication and pricing areas from technical and administrative point of view in order to improve the system and provide better service to the users. Thus, the added value obtained from the CORS-TR System has been increased and contributed to the more efficient use of country resources. In this paper, how the technical, administrative and financial studies in the operation of the CORS-TR System were managed with a sustainable business model, studies for solving problems encountered in operating of the system, the cost / benefit analysis of the system and the sharing of experience gained from the perspective of how web-based applications are managed and the business model of the CORS-TR System are explained in detail.

  2. Nucleotide sequence of atpB, rbcL, trnR, dedB and psaI chloroplast genes from a fern Angiopteris lygodiifolia: a possible emergence of Spermatophyta lineage before the separation of Bryophyta and Pteridophyta.

    Science.gov (United States)

    Yoshinaga, K; Kubota, Y; Ishii, T; Wada, K

    1992-01-01

    To elucidate the evolutionary relationship between the Spermatophyta, Pteridophyta and Bryophyta, we cloned a fragment of chloroplast DNA from the fern Angiopteris lygodiifolia (Pteridophyta) and determined its nucleotide sequence. The fragment contained the atpB, rbcL, trnR-CCG, dedB and psaI genes. Comparisons of the deduced amino acid and nucleotide sequences of these genes from the three plant groups indicate that Angiopteris sequences are more closely related to those of Bryophyta species (85% identity on average) than to those of seed plants (76% identity on average), supporting a hypothesis that the Bryophyta and Pteridophyta diverged more recently from one another than their common progenitor diverged from that of the Spermatophyta.

  3. Ka-Band MMIC T/R Module, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — This Phase II proposal is presented as the follow on to the Phase I SBIR contract number NNC06CB21C entitled "Ka-band MMIC T/R Module" For active microwave...

  4. L and P Band MMIC T/R Module Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposal is specifically written to address the need for improved L and P band T/R modules. The solicitation calls for investigation and development of core...

  5. L and P Band MMIC T/R Module Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposal is specifically written to address the need for improved L and P band T/R modules for use in active microwave surveillance of earth surface and...

  6. Maximum credible accident analysis for TR-2 reactor conceptual design

    International Nuclear Information System (INIS)

    Manopulo, E.

    1981-01-01

    A new reactor, TR-2, of 5 MW, designed in cooperation with CEN/GRENOBLE is under construction in the open pool of TR-1 reactor of 1 MW set up by AMF atomics at the Cekmece Nuclear Research and Training Center. In this report the fission product inventory and doses released after the maximum credible accident have been studied. The diffusion of the gaseous fission products to the environment and the potential radiation risks to the population have been evaluated

  7. Detected Timing for Exoplanet TrES-5b. Possible Existence of Exoplanet TrES-5c

    Science.gov (United States)

    Sokov, E. N.; Sokova, I. A.; Dyachenko, V. V.; Rastegaev, D. A.; Rusov, S. A.

    2017-06-01

    In this paper, we present timing variations detected for the TrES-5b exoplanet. To obtain necessary photometric data for this exoplanet, we have organized an international campaign for exoplanet searching based on the Transit Timing Variation (TTV) method. We managed to collect N light curves for TrEs-5b. On the basis of the obtained data, we detected timing variations with the period P ≍ 100 days. We carried out the N-body modelling by means of the three-body problem. We detected a perturbation of TrES-5b which can be caused by a second exoplanet in the TrES-5 system. We calculated possible masses and resonances of the objects: M ˜ 0.24 Mjup on the 1:2 Resonance and M ˜ 3.15 Mjup on the 1:3 Resonance.

  8. A ironia trágica de Machado de Assis

    Directory of Open Access Journals (Sweden)

    Patrick Pessoa

    2007-04-01

    Full Text Available O texto defende, a partir de uma análise das Memórias póstumas de Brás Cubas, de Machado de Assis, que a ironia do autor deve ser lida como uma espécie de ironia trágica. A fundamentação dessa hipótese é realizada em três etapas: na primeira, apresenta-se o conceito de ironia trágica, como tematizado por Christoph Menke e Wayne Booth; na segunda, mostra-se como a noção de ironia trágica permite compreender a célebre definição de Lukács de que “a ironia é a objetividade do romance”; finalmente, o texto discute como o conceito de ironia trágica ao mesmo tempo esclarece e subverte as interpretações tradicionais da obra de Machado de Assis.

  9. ITRANS Simulador de trânsito 3D

    OpenAIRE

    Gonçalves de Barros, Paulo

    2005-01-01

    O planejamento de tráfego urbano tem um papel fundamental na sociedade atual, pois permite um melhor aproveitamento das vias de tráfego e otimiza o fluxo de veículos e pedestres. Este planejamento também reduz engarrafamentos, períodos de viagem e poluição, ajudando não só a economia, mas a população, através da garantia de uma melhor qualidade de vida. A fim de solucionar os problemas do tráfego, diversos modelos matemáticos foram criados. O advento do computador fez com que esses modelos...

  10. Síndrome do osso trígono

    OpenAIRE

    Moura, D; Gaspar, AR; Mariano, C; Judas, F

    2015-01-01

    A causa mais frequente da síndrome de conflito posterior do tornozelo envolve o osso trígono e o processo talar, chamando-se síndrome do osso trígono à compressão sintomática de tecidos moles e osso a nível do intervalo calcâneo-tibial. Trata-se de uma entidade controversa, atualmente ainda com evidência limitada na literatura. A presença do osso trígono é na maior parte dos casos apenas um achado imagiológico sem tradução clínica, no entanto o seu traumatismo, agudo ou crónico, em movimentos...

  11. Canal de Mensagens de Trânsito

    OpenAIRE

    Egon Cervieri Guterres

    2010-01-01

    Informe Setorial: O Canal de Mensagens de Trânsito (Traffic Message Channel - TMC) é uma padronização internacional para a distribuição de informações (conteúdo) sobre a situação do trânsito urbano local e inter-regional, em tempo real, de forma eletrônica e diretamente aos motoristas. Traz para os cidadãos, em mensagens eletrônicas simples e acessíveis, informações sobre congestionamentos, acidentes, obras na pista, problemas climáticos (alagamentos, asfalto escorregadio, nevoeiro...) e desv...

  12. Três Versões de Orfeu

    Directory of Open Access Journals (Sweden)

    Thais Flores Nogueira Diniz

    2001-12-01

    Full Text Available Ao se analisarem três criações intertextuais cujo tema é o mito de Orfeu retratam-se três momentos da história brasileira, levando-se em cona elementos do mito e rubricas da peça que serviu de “origem” para os dois filmes. Conclui-se que não só a música e a arte brasileira são louvadas, mas também, através delas, a identidade nacional é retratada.

  13. Mixed trTLEP-structures and mixed Frobenius structures

    OpenAIRE

    Shamoto, Yota

    2015-01-01

    We introduce the notion of mixed trTLEP-structures and prove that a mixed trTLEP-structure with some conditions naturally induces a mixed Frobenius manifold. This is a generalization of the reconstruction theorem of Hertling and Manin. As a special case, we also show that a graded polarizable variation of mixed Hodge structure with $H^2$-generation condition gives rise to a family of mixed Frobenius manifolds. It implies that there exist mixed Frobenius manifolds associated to local B-models.

  14. A molecular phylogenetic and fruit evolutionary analysis of the major groups of the paleotropical woody bamboos (Gramineae: Bambusoideae) based on nuclear ITS, GBSSI gene and plastid trnL-F DNA sequences.

    Science.gov (United States)

    Yang, Han-Qi; Yang, Jun-Bo; Peng, Zhen-Hua; Gao, Jian; Yang, Yu-Ming; Peng, Sheng; Li, De-Zhu

    2008-09-01

    This study presented the first molecular phylogenetic analysis of the major clades of woody bamboos of the Old World tropics based on nuclear and chloroplast sequences (ITS, GBSSI and trnL-F). Sequence data from 53 species, representing 17 paleotropical woody bamboo genera, were analyzed using the maximum parsimony and Bayesian inference methods. All examined ingroup taxa were clustered into two clades, i.e., the Bambusinae+Dinochloa clade and the Melocanninae clade. The former clade included Bambusa, Bonia, Dendrocalamus, Dendrocalamopsis, Dinochloa, Gigantochloa, Molecalamus, Neomicrocalamus, Neosinocalamus, Oxytenanthera s. str. (sensu stricto), Racemobambos and Thyrsostachys. The Melocanninae clade consisted of Cephalostachyum, Leptocanna (better treated as part of Cephalostachyum), Melocanna, Pseudostachyum and Schizostachyum s. str. The subtribe Racemobambosinae and tribes Dendrocalameae and Oxytenanthereae were not supported and may be better placed in subtribe Bambusinae. The ovary characters seemed to be good criteria to distinguish these two clades. The reconstruction of ancestral fruit characters indicated that the bacoid caryopsis, namely, fleshy or berry-like fruits, was found to be scattered in three lineages of the examined paleotropical woody bamboos. Fruit characters are thus not reliable indicators of phylogeny and bacoid caryopsis likely represents a specialization for particular ecological conditions.

  15. Integrated L-Band T/R Module Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The goal of this Phase II project is to deliver an integrated L-band transmit/receive (T/R) module which will be fabricated from a GaAs-based combined HBT/PHEMT...

  16. Korroderede trådbindere i murværk

    DEFF Research Database (Denmark)

    Hansen, Klavs Feilberg

    Denne SBi-anvisning omdhandler korroderede trådbindere i hule mure og skalmure, og den nedstyrtningsfare som korrosionen kan medføre. Anvisningen beskriver metoder til at undersøge og vurdere problemet, og hvordan man kan eftermontere nye bindere. Anvisningen er rettet mod rådgivende ingeniører....

  17. Træernes rolle i et landbrugslandskab i Senegal

    DEFF Research Database (Denmark)

    Pedersen, Jens Christian

    2010-01-01

    Ved at gå ind i et eksisterende projektsamarbejde er det lykkedes Steen Christensen at gennemføre et vellykket feltarbejde i Senegal inden for et 6-måneders speciale. Resultaterne fra projektet vil kunne indgå som grundlag for en lokal forvaltning som tager sigte på at beskytte træerne som er en...

  18. Counsellors Respond to the DSM-IV-TR

    Science.gov (United States)

    Strong, Tom; Gaete, Joaquin; Sametband, Ines N.; French, Jared; Eeson, Jen

    2012-01-01

    The Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) is an administrative fact for many counsellors. This psychiatric approach to formulating client concerns runs counter to those used by counsellors of many approaches (e.g., systemic, feminist). Using an online survey of counsellors (N = 116), invited contributions to a website…

  19. Ajast ja arust trükikoda Kultuuritehases / Merit Kask

    Index Scriptorium Estoniae

    Kask, Merit

    2006-01-01

    Tallinna Kultuuritehase trükikojas toimunud kõrgtrükitehnikas käsilao õpikojast. Juhendaja inglise kunstnik Pete Nevin, osa võtsid Eesti Kunstiakadeemia tudengid (nimed), kelle tehtud tööd on samas näitusel

  20. TrED: the Trichophyton rubrum Expression Database

    Directory of Open Access Journals (Sweden)

    Liu Tao

    2007-07-01

    Full Text Available Abstract Background Trichophyton rubrum is the most common dermatophyte species and the most frequent cause of fungal skin infections in humans worldwide. It's a major concern because feet and nail infections caused by this organism is extremely difficult to cure. A large set of expression data including expressed sequence tags (ESTs and transcriptional profiles of this important fungal pathogen are now available. Careful analysis of these data can give valuable information about potential virulence factors, antigens and novel metabolic pathways. We intend to create an integrated database TrED to facilitate the study of dermatophytes, and enhance the development of effective diagnostic and treatment strategies. Description All publicly available ESTs and expression profiles of T. rubrum during conidial germination in time-course experiments and challenged with antifungal agents are deposited in the database. In addition, comparative genomics hybridization results of 22 dermatophytic fungi strains from three genera, Trichophyton, Microsporum and Epidermophyton, are also included. ESTs are clustered and assembled to elongate the sequence length and abate redundancy. TrED provides functional analysis based on GenBank, Pfam, and KOG databases, along with KEGG pathway and GO vocabulary. It is integrated with a suite of custom web-based tools that facilitate querying and retrieving various EST properties, visualization and comparison of transcriptional profiles, and sequence-similarity searching by BLAST. Conclusion TrED is built upon a relational database, with a web interface offering analytic functions, to provide integrated access to various expression data of T. rubrum and comparative results of dermatophytes. It is devoted to be a comprehensive resource and platform to assist functional genomic studies in dermatophytes. TrED is available from URL: http://www.mgc.ac.cn/TrED/.

  1. Structure of Triton's atmosphere from the occultation of Tr176

    Science.gov (United States)

    Sicardy, B.; Mousis, O.; Beisker, W.; Hummel, E.; Hubbard, W. B.; Hill, R.; Reitsema, H. J.; Anderson, P.; Ball, L.; Downs, B.; Hutcheon, S.; Moy, M.; Nielsen, G.; Pink, I.; Walters, R.

    1998-09-01

    The occultation of the star Tr176 by Triton (Mc Donald & Elliot, AJ 109, 1352, 1995) was observed on 18 July 1997 from three stations in Queensland, Australia (Bundaberg, Ducabrook and Lochington) and one station in Texas, USA (Brownsville). All observations were made with CCD (no filter) and with portable C14 telescopes, except at Bundaberg, where a fixed 48-cm telescope was used. Time sampling rate ranges from 0.33 sec (Bundaberg) to 0.66 sec (Ducabrook and Lochington), with the intermediate value 0.5 sec at Brownsville. Isothermal fits were performed to the lightcurves in order to determine the isothermal temperature, T_iso, and the radius at half-level, R_{1/2}, of Triton's atmosphere (assumed to be composed of pure N_2). Considering the level of noise, we cannot detect any departure from isothermal profiles, and we do not see any deviations from spherical shape. A global fit yields T_iso = 53.7 +/- 2 K and R_{1/2} = 1456 +/- 3 km. We also derive the pressure at 1400 km: p1400 = 1.9 +/- 0.3 mu bars. We will discuss these results and compare them with previous works obtained by Voyager teams from the 1989 observations, and by Olkin et al. (Icarus 129, 178, 1997), who analyze two Triton occultations observed in July 1993 (Tr60) and August 1995 (Tr148). We observe a general increase of pressure at 1400 km, since Olkin et al. derive p1400 = 1.4 +/- 0.1 mu bars from the Tr148 event. This result is actually confirmed by a recent work by Elliot et al., (Nature 393, 765 1998), who note a global warming on Triton, based in particular on a new HST occultation observation in November 1997 (Tr180).

  2. Paracoccidioidomicose palpebral: relato de três casos

    Directory of Open Access Journals (Sweden)

    Rocha Guilherme José Nunes Marques

    2002-01-01

    Full Text Available Objetivo: Relato clínico-patológico de três casos de paracoccidioidomicose multifocal comprometendo pálpebra e secundariamente a conjuntiva em dois deles. Métodos: Revisão dos prontuários e preparações histopatológicas obtidas das biópsias. Resultado: O estudo histopatológico realizado nos três casos, evidenciou reação inflamatória de tipo granulomatoso. A coloração pelo método de Grocott demonstrou a presença do Paracoccidioides brasiliensis. Conclusão: É importante a inclusão da paracoccidioidomicose no diagnóstico diferencial de lesões tumorais acometendo as pálpebras.

  3. La Universidad de Costa Rica en tránsito

    Directory of Open Access Journals (Sweden)

    Badilla Saxe, Eleonora

    2012-02-01

    Full Text Available Resumen. La Universidad de Costa Rica en Tránsito es un artículo que pretende dar cuenta del tránsito que ha iniciado la institución en su camino hacia la transdisciplinariedad. Se presenta, en primera instancia, un contexto histórico y referentes teóricos que apuntan a que la Universidad en el Siglo XXI debe iniciar un tránsito, por una parte, de regreso a reflejar el significado de su origen: UNIVERSUS-A-UM (“todo”, “entero”, “universal” superando fragmentaciones y departamentalizaciones y, por otro, hacia una visión transdisciplinar, un pensamiento complejo en sintonía con las realidades biológicas, sociales y culturales del mundo en el siglo XXI. Y, ya que la transdisciplinariedad no se puede llevar a cabo más que en la acción y en la interacción con otros, se reporta sobre una serie de estrategias interconectadas que se están promoviendo Universidad de Costa Rica para ayudar a la institución a iniciar ese tránsito.Abstract. University of Costa Rica in Transit is an article that reports on the journey the institution has started on its path towards transdisciplinarity. On one way, back to the origen: universus (all, whole, universal, overcoming fragmentation and departamentalization. On the other towards a transdisciplinary vision and complex thinking in accordance with the new biological, social and cultural realities of our world. Interactive and interrelated strategies that are currently beeing promoted to stimulate the institution towards transdisciplinarity are reported here. It is important to remember that transdisciplinarity can only be reflected in action, and in the interaction with others.

  4. Efficient inverse position transformation for TR 4000S robot manipulator

    Directory of Open Access Journals (Sweden)

    Kesheng Wang

    1989-04-01

    Full Text Available An efficient method is developed for computing the inverse kinematic position solution with a closed form for the TR 4000S spray painting robot manipulator with five degrees of freedom and non-spherical wrist construction. The inverse kinematic problem is defined as the transformation from Cartesian space to the joint space. The solution is based on the geometrical separation of the arm and wrist of a robot manipulator and shows that it is very systematic, efficient and easily derived.

  5. Fysisk træning på psykomotorikuddannelsen

    DEFF Research Database (Denmark)

    Flammild, Manja

    2012-01-01

    rolle i sundhedsfremme og forebyggelse, og ønsket er, at viden fra faget kan rettes mod forskellige målgrupper? Problemformuleringen undersøges med fokus på forskellige målgrupper, om end at læringsmålet i fysisk træning primært er rettet mod voksne inden for normalområdet. Der kigges særligt på...

  6. TrSDB: a proteome database of transcription factors

    Science.gov (United States)

    Hermoso, Antoni; Aguilar, Daniel; Aviles, Francesc X.; Querol, Enrique

    2004-01-01

    TrSDB—TranScout Database—(http://ibb.uab.es/trsdb) is a proteome database of eukaryotic transcription factors based upon predicted motifs by TranScout and data sources such as InterPro and Gene Ontology Annotation. Nine eukaryotic proteomes are included in the current version. Extensive and diverse information for each database entry, different analyses considering TranScout classification and similarity relationships are offered for research on transcription factors or gene expression. PMID:14681387

  7. Marinization concept for the TRICEPT TR600 robot

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, A.; Aust, E.; Niemann, H.R.; Santos, J.F. dos [GKSS-Forschungszentrum Geesthacht GmbH (Germany). Inst. fuer Materialforschung; Hammerin, R.; Neumann, K.E. [Neos Robotics AB, Taeby (Sweden); Gibson, D. [National Hyperbaric Centre, Aberdeen (United Kingdom)

    1998-11-01

    The need for automated welding repair systems of marine structures, ship hulls and nuclear installations had lead to an increasing demand for subsea robots. Considering the application of friction welding to perform underwater repairs, a TRICEPT TR600 robot has been identified as the most suitable system to withstand the high reaction forces characteristic of this process. This study reviews initially the research and development work carried out at GKSS to modify and test a Siemens-MANUTEC robot. After a description of the TRICEPT TR600 robot a marinization concept is presented and discussed in detail. Problems of galvanic corrosion in seawater are addressed in a separate chapter. The deflection of the robot in subsea water currents is estimated with a worst-case calculation. (orig.) [Deutsch] Der Wunsch, Roboter auch unter Wasser einsetzen zu koennen, waechst mit steigendem Interesse nach automatisierten Schweissverfahren fuer Reparaturen an marinen Bauwerken, Schiffsruempfen und in Kernenergieanlagen. Fuer den Einsatz von Reibschweissverfahren fuer diese Reparaturen wurde der TRICEPT TR600-Roboter ausgewaehlt, da dieser auch den charakteristisch hohen Prozesskraeften widerstehen kann. Die notwendigen Modifikationen und Pruefungen werden beispielhaft anhand des bei der GKSS modifizierten Siemens-MANUTEC-Roboters vorgestellt. Nach einer Beschreibung des TRICEPT-Roboters werden die notwendigen Umbaumassnahmen detailliert dargestellt und diskutiert. Auf die Problematik der galvanischen Korrosion in Seewasser wird in einem gesonderten Kapitel naeher eingegangen. Zusaetzlich wird eine moegliche Ablenkung des Roboters durch Wasserstroemung ueberschlaegig berechnet. (orig.)

  8. DW4TR: A Data Warehouse for Translational Research.

    Science.gov (United States)

    Hu, Hai; Correll, Mick; Kvecher, Leonid; Osmond, Michelle; Clark, Jim; Bekhash, Anthony; Schwab, Gwendolyn; Gao, De; Gao, Jun; Kubatin, Vladimir; Shriver, Craig D; Hooke, Jeffrey A; Maxwell, Larry G; Kovatich, Albert J; Sheldon, Jonathan G; Liebman, Michael N; Mural, Richard J

    2011-12-01

    The linkage between the clinical and laboratory research domains is a key issue in translational research. Integration of clinicopathologic data alone is a major task given the number of data elements involved. For a translational research environment, it is critical to make these data usable at the point-of-need. Individual systems have been developed to meet the needs of particular projects though the need for a generalizable system has been recognized. Increased use of Electronic Medical Record data in translational research will demand generalizing the system for integrating clinical data to support the study of a broad range of human diseases. To ultimately satisfy these needs, we have developed a system to support multiple translational research projects. This system, the Data Warehouse for Translational Research (DW4TR), is based on a light-weight, patient-centric modularly-structured clinical data model and a specimen-centric molecular data model. The temporal relationships of the data are also part of the model. The data are accessed through an interface composed of an Aggregated Biomedical-Information Browser (ABB) and an Individual Subject Information Viewer (ISIV) which target general users. The system was developed to support a breast cancer translational research program and has been extended to support a gynecological disease program. Further extensions of the DW4TR are underway. We believe that the DW4TR will play an important role in translational research across multiple disease types. Copyright © 2011 Elsevier Inc. All rights reserved.

  9. The Test Reactor Embrittlement Data Base (TR-EDB)

    International Nuclear Information System (INIS)

    Stallmann, F.W.; Kam, F.B.K.; Wang, J.A.

    1993-01-01

    The Test Reactor Embrittlement Data Base (TR-EDB) is part of an ongoing program to collect test data from materials irradiations to aid in the research and evaluation of embrittlement prediction models that are used to assure the safety of pressure vessels in power reactors. This program is being funded by the US Nuclear Regulatory Commission (NRC) and has resulted in the publication of the Power Reactor Embrittlement Data Base (PR-EDB) whose second version is currently being released. The TR-EDB is a compatible collection of data from experiments in materials test reactors. These data contain information that is not obtainable from surveillance results, especially, about the effects of annealing after irradiation. Other information that is only available from test reactors is the influence of fluence rates and irradiation temperatures on radiation embrittlement. The first version of the TR-EDB will be released in fall of 1993 and contains published results from laboratories in many countries. Data collection will continue and further updates will be published

  10. Três Tópicos em economia comportamental

    OpenAIRE

    Carvalho, Mateus Libardi de

    2013-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Sócio-Econômico, Programa de Pós-Graduação em Economia, Florianópolis, 2013. Esta dissertação apresenta três tópicos em economia comportamental. O primeiro trata de verificar se há correlação entre orientação de valor social e escolha intertemporal. Observou-se que indivíduos mais pró-sociais tendem a ser mais pacientes. O segundo trata de alterar o teste conhecido por CRT (Cognitive Reflexion Test), objetivando verifi...

  11. Posttranslational Control of ALA Synthesis Includes GluTR Degradation by Clp Protease and Stabilization by GluTR-Binding Protein.

    Science.gov (United States)

    Apitz, Janina; Nishimura, Kenji; Schmied, Judith; Wolf, Anja; Hedtke, Boris; van Wijk, Klaas J; Grimm, Bernhard

    2016-04-01

    5-Aminolevulinic acid (ALA) is the first committed substrate of tetrapyrrole biosynthesis and is formed from glutamyl-tRNA by two enzymatic steps. Glutamyl-tRNA reductase (GluTR) as the first enzyme of ALA synthesis is encoded by HEMA genes and tightly regulated at the transcriptional and posttranslational levels. Here, we show that the caseinolytic protease (Clp) substrate adaptor ClpS1 and the ClpC1 chaperone as well as the GluTR-binding protein (GBP) interact with the N terminus of GluTR Loss-of function mutants of ClpR2 and ClpC1 proteins show increased GluTR stability, whereas absence of GBP results in decreased GluTR stability. Thus, the Clp protease system and GBP contribute to GluTR accumulation levels, and thereby the rate-limiting ALA synthesis. These findings are supported with Arabidopsis (Arabidopsis thaliana) hema1 mutants expressing a truncated GluTR lacking the 29 N-terminal amino acid residues of the mature protein. Accumulation of this truncated GluTR is higher in dark periods, resulting in increased protochlorophyllide content. It is proposed that the proteolytic activity of Clp protease counteracts GBP binding to assure the appropriate content of GluTR and the adequate ALA synthesis for chlorophyll and heme in higher plants. © 2016 American Society of Plant Biologists. All Rights Reserved.

  12. A short proof of a conjecture on the Tr-choice number of even cycles

    NARCIS (Netherlands)

    Sitters, R. A.

    In this note we prove that the Tr-choice number of the cycle C2n is equal to the Tr-choice number of the path (tree) on 4n - 1 vertices, i.e. Tr-ch(C2n) = [((4n - 2)/(4n - 1))(2r + 2)] + 1. This solves a recent conjecture of Alon and Zaks.

  13. Macrolide resistance gene erm(TR) and erm(TR)-carrying genetic elements in Streptococcus agalactiae: characterization of ICESagTR7, a new composite element containing IMESp2907.

    Science.gov (United States)

    Mingoia, Marina; Morici, Eleonora; Marini, Emanuela; Brenciani, Andrea; Giovanetti, Eleonora; Varaldo, Pietro E

    2016-03-01

    The objective of this study was to investigate macrolide-resistant Streptococcus agalactiae isolates harbouring erm(TR), an erm(A) gene subclass, with emphasis on their erm(TR)-carrying genetic elements. Four erm(TR)-carrying elements have been described to date: three closely related (ICE10750-RD.2, Tn1806 and ICESp1108) in Streptococcus pyogenes, Streptococcus pneumoniae and S. pyogenes, respectively; and one completely different (IMESp2907, embedded in ICESp2906 to form ICESp2905) in S. pyogenes. Seventeen macrolide-resistant erm(TR)-positive S. agalactiae isolates were phenotypically and genotypically characterized. Their erm(TR)-carrying elements were explored by analysing the distinctive recombination genes of known erm(TR)-carrying integrative and conjugative elements (ICEs) and by PCR mapping. The new genetic context and organization of IMESp2907 in S. agalactiae were explored using several experimental procedures and in silico analyses. Five isolates harboured ICE10750-RD.2/Tn1806, five isolates harboured ICESp1108 and five isolates bore unknown erm(TR)-carrying elements. The remaining two isolates, exhibiting identical serotypes and pulsotypes, harboured IMESp2907 in a new genetic environment, which was further investigated in one of the two isolates, SagTR7. IMESp2907 was circularizable in S. agalactiae, as described in S. pyogenes. The new IMESp2907 junctions were identified based on its site-specific integration; the att sites were almost identical to those in S. pyogenes. In strain SagTR7, erm(TR)-carrying IMESp2907 was embedded in an erm(TR)-less internal element related to ICE10750-RD.2/Tn1806, which, in turn, was embedded in an ICESde3396-like element. The resulting whole ICE, ICESagTR7 (∼129 kb), was integrated into the chromosome downstream of the rplL gene, and was excisable in circular form and transferable by conjugation. This is the first study exploring erm(TR)-carrying genetic elements in S. agalactiae. © The Author 2015. Published by

  14. Tallinna linna- ja gümnaasiumi trükikoda ehk 380 aastat trükikunsti Tallinnas / Aija Sakova-Merivee

    Index Scriptorium Estoniae

    Sakova-Merivee, Aija, 1980-

    2015-01-01

    Alanud aasta alguses esitlesid Tallinna Ülikooli Akadeemiline Raamatukogu ja Tallinna Linnaarhiiv ühist trükist „Tallinna linna- ja gümnaasiumi trükikoda (1634–1828). Näituse kataloog”. Autor annab ülevaate nii näitusest kui selle kataloogist

  15. Riso imotivado: relato de três casos

    Directory of Open Access Journals (Sweden)

    Paulo Henrique F. Bertolucci

    1985-03-01

    Full Text Available Os autores fazem uma revisão das causas e fisiopatologia do riso imoti-vado e de sua classificação. São apresentados três casos de riso imotivado. Um em que o distúrbio está associado a alterações motoras e sensitivas ocorrendo em crises diferentes entre si e sempre seguidas de recuperação integral, no qual foi feito o diagnóstico de esclerose múltipla. No segundo caso o riso estava associado a déficit motor e livedo reticular, tendo sido feito o diagnóstico de vasculite. No terceiro caso havia associação com paresia facial central à direita, em paciente diabético e hipertenso, com evidência de comprometimento vascular em outras áreas, tendo sido feito o diagnóstico de doença cerebrovascular.

  16. Vi tar pulsen på trærne

    OpenAIRE

    Børja, Isabella; Clarke, Nicholas; Dreslerová, J; Eldhuset, Toril Drabløs; Gebauer, Roman; Gryc, V; Krokene, Paal; Nagy, Nina Elisabeth; Urban, J; Volařík, Daniel

    2010-01-01

    Tørkestress hos gran ser ut til å bli et stadig større problem i mange europeiske land. På Skog og landskap har vi et EØS-samarbeidsprosjekt med tsjekkiske forskere fra Mendel-universitetet i Brno hvor vi i detalj undersøker hva som skjer i tørkestressede grantrær. Målet er å kartlegge vannførende mekanismer hos trær som er tørkestresset. Vi arbeider med 20 år gamle kloner av gran og simulerer tørke ved å bygge et tak under trekronene. Her bruker vi avansert instrumentering for å følge med på...

  17. Colombia: ¿una sociedad trágica?

    Directory of Open Access Journals (Sweden)

    Sandro Romero Rey

    2014-10-01

    Full Text Available El texto forma parte de una reflexión sobre las especificidades de las ideas de tragedia y lo trágico dentro del conflicto colombiano contemporáneo. A partir de los elementos esenciales del teatro griego asociados al género y a la dimensión de la fatalidad, el presente texto establece relaciones entre los referentes de los mitos antiguos y sus equivalencias en una sociedad específica de América Latina. Los personajes de la tragedia griega se convierten en una suerte de metáforas vivas que continúan interrogando al hombre más allá de los límites de su tiempo.

  18. Measuring heat transfer through TR-0 reactor fuel element

    International Nuclear Information System (INIS)

    Nemec, V.; Turzik, Z.; Vitek, M.

    1977-05-01

    The time course of temperatures of the peripheral and the central fuel pins of the TR-O reactor was studied during moderator temperature changes using a model. The formula T=Tsub(e)+(Tsub(o)-Tsub(e)).exp(-t/tsub(e)) applies, where T is the pin temperature, Tsub(o) the initial pin temperature, Tsub(e) is the steady-state bath temperature, tsub(e) the time constant of temperature equilibration and t the time required for a temperature change from value Tsub(o) to T. For the bath level height H=1 m the tsub(e) value for the central pin was determined to be 1.05 hours, for the peripheral pin 0.96 hour; for level height H=2 m the values were 2.1 and 2.12 hours, respectively. The dependence found will allow correcting the experimental results in measurements with heated moderator for fuel temperature changes. (Ha)

  19. Displasia fibrosa: relato de três casos

    Directory of Open Access Journals (Sweden)

    Alves Adriana L.

    2002-01-01

    Full Text Available A displasia fibrosa é lesão pseudo-neoplásica de etiologia desconhecida, caráter benigno e recidivante, caracterizada pelo desenvolvimento de tecido fibroso e traves osteóides que substituem gradualmente o osso normal. O principal diagnóstico diferencial da forma monostótica, no envolvimento dos ossos da cabeça e pescoço, é o fibroma ossificante, que alguns consideram variante desta entidade. Esse trabalho tem como objetivo revisar as principais características clínicas, radiológicas e histopatológicas que auxiliam no diagnóstico diferencial da displasia fibrosa com o fibroma ossificante e discutir o comportamento recidivante da displasia fibrosa, essencial ao planejamento cirúrgico. Relatamos três casos provenientes do ambulatório de Otorrinolaringologia da Santa Casa de Misericórdia de São Paulo, avaliados quanto às queixas, exame físico, achados de imagem e tratamentos. Nos três casos o diagnóstico foi confirmado pelo exame anatomopatológico. Todos apresentaram recidiva após a ressecção cirúrgica, diagnosticada entre o primeiro e o oitavo ano de seguimento. Devido ao comportamento clínico semelhante da displasia fibrosa e do fibroma ossificante, o exame anatomopatológico é essencial para o diagnóstico diferencial. O acompanhamento clínico permanente desses pacientes é necessário para que as possíveis recidivas sejam diagnosticadas precocemente.

  20. Multiple isoforms of β-TrCP display differential activities in the regulation of Wnt signaling

    Science.gov (United States)

    Seo, Eunjeong; Kim, Hyunjoon; Kim, Rokki; Yun, Sangmoon; Kim, Minseong; Han, Jin-Kwan; Costantini, Frank; Jho, Eek-hoon

    2008-01-01

    The F-box proteins β-TrCP 1 and 2 (β-transducin repeat protein) have 2 and 3 isoforms, respectively, due to alternative splicing of exons encoding the N-terminal region. We identified an extra exon in between the previously known exons 1 and 2 of β-TrCP1 and β-TrCP2. Interestingly, sequence analysis suggested that many more isoforms are produced than previously identified, via the alternative splicing of all possible combination of exons II to V of β-TrCP1 and exons II to IV of β-TrCP2. Different mouse tissues show specific expression patterns of the isoforms, and the level of expression of the isoform that has been used in most published papers was very low. Yeast two-hybrid assays show that β-TrCP1 isoforms containing exon III, which are the most highly expressed isoforms in most tissues, do not interact with Skp1. Indirect immunofluorescence analysis of transiently expressed β-TrCP1 isoforms suggests that the presence of exon III causes β-TrCP1 to localize in nuclei. Consistent with the above findings, isoforms including exon III showed a reduced ability to block ectopic embryonic axes induced via injection of Wnt8 or β-catenin in Xenopus embryos. Overall, our data suggest that isoforms of β-TrCPs generated by alternative splicing may have different biological roles. PMID:18929646

  1. TR-EDB: Test Reactor Embrittlement Data Base, Version 1

    International Nuclear Information System (INIS)

    Stallmann, F.W.; Wang, J.A.; Kam, F.B.K.

    1994-01-01

    The Test Reactor Embrittlement Data Base (TR-EDB) is a collection of results from irradiation in materials test reactors. It complements the Power Reactor Embrittlement Data Base (PR-EDB), whose data are restricted to the results from the analysis of surveillance capsules in commercial power reactors. The rationale behind their restriction was the assumption that the results of test reactor experiments may not be applicable to power reactors and could, therefore, be challenged if such data were included. For this very reason the embrittlement predictions in the Reg. Guide 1.99, Rev. 2, were based exclusively on power reactor data. However, test reactor experiments are able to cover a much wider range of materials and irradiation conditions that are needed to explore more fully a variety of models for the prediction of irradiation embrittlement. These data are also needed for the study of effects of annealing for life extension of reactor pressure vessels that are difficult to obtain from surveillance capsule results

  2. Nietzsche e o renascimento do trágico

    Directory of Open Access Journals (Sweden)

    Roberto Machado

    2005-12-01

    Full Text Available O objetivo deste artigo é expor como a proposta de renascimento do trágico existente em O nascimento da tragédia insere o primeiro livro de Nietzsche no projeto cultural iniciado por Winckelmann, Goethe e Schiller, na segunda metade do século XVIII, que privilegia a arte grega como modelo da arte alemã. Destacarei, para isso, tanto as continuidades entre os dois momentos quanto as descontinuidades que Nietzsche introduz nesse projeto clássico da intelectualidade alemã ao pensar a cultura grega a partir da filosofia de Schopenhauer e da música de Wagner.The purpose of this article is to discuss Nietzsche's theory on the rebirth of the tragic presented in his early writings as part of the German cultural project introduced by Winckelmann, Goethe and Schiller in the second half of the 18th century. Departing from the idea that this project established Greece as a model to be followed by Germany, I will point out Nietzsche's supporting views to it as well as his innovative idea of bringing together the philosophy of Schopenhauer and the music of Wagner to think the Greek culture.

  3. TR-EDB: Test Reactor Embrittlement Data Base, Version 1

    Energy Technology Data Exchange (ETDEWEB)

    Stallmann, F.W.; Wang, J.A.; Kam, F.B.K. [Oak Ridge National Lab., TN (United States)

    1994-01-01

    The Test Reactor Embrittlement Data Base (TR-EDB) is a collection of results from irradiation in materials test reactors. It complements the Power Reactor Embrittlement Data Base (PR-EDB), whose data are restricted to the results from the analysis of surveillance capsules in commercial power reactors. The rationale behind their restriction was the assumption that the results of test reactor experiments may not be applicable to power reactors and could, therefore, be challenged if such data were included. For this very reason the embrittlement predictions in the Reg. Guide 1.99, Rev. 2, were based exclusively on power reactor data. However, test reactor experiments are able to cover a much wider range of materials and irradiation conditions that are needed to explore more fully a variety of models for the prediction of irradiation embrittlement. These data are also needed for the study of effects of annealing for life extension of reactor pressure vessels that are difficult to obtain from surveillance capsule results.

  4. Georges et les trésors du cosmos

    CERN Document Server

    Hawking, Lucy; Parsons, Gary

    2011-01-01

    Les voisins excentriques de Georges, Annie et Eric, ont déménagé en Floride à l'agence Spatiale Globale. Là-bas, Eric s'occupe de son nouveau robot, Homer, qui doit détécter les signes de vie sur Mars. Mais bientôt, Georges reçoit un e-mail : Annie lui demande de la rejoindre au plus vite pour une " mission cosmique " secrète. La jeune fille est persuadée qu'il se passe de drôles de choses sur Mars, car Homer vient de recevoir un message extraterrestre ! Georges et Anne (avec l'aide d'Emmett, un petit garçon bizarre) décident de réparer Cosmos, leur super-ordinateur, et d'aller voir par eux-mêmes... Emmaillotés dans des combinaisons spéciales, ils se lancent alors dans une fabuleuse chasse aux trésors sur Mars, sur les lunes de Saturne, puis sur Titan, avant de se perdre en orbite autour d'Alpha Centauri B... Mais avant de pouvoir élucider le mystère du message extraterrestre, Georges et Annie devront se livrer à une bataille spatiale acharnée qui mettra leur vie en danger, ainsi que ce...

  5. Flexible piezoelectric nanogenerators based on PVDF-TrFE nanofibers

    Science.gov (United States)

    Serairi, Linda; Gu, Long; Qin, Yong; Lu, Yingxian; Basset, Philippe; Leprince-Wang, Yamin

    2018-01-01

    In this paper, electrospun piezoelectric PVDF-TrFE nanofibers were used for the fabrication of two types of flexible nanogenerator (NG) devices based on the direct piezoelectric effect, allowing the conversion of mechanical energy into electrical energy. The first one is composed of quite well aligned thin film nanofibers of about 35 μm and the second one is composed of random nanofibers of about 50 μm. The influence of the applied stress and strain rate on the output for both types of NG was studied. It is shown that the pulse peaks generated by NG increase with the applied mechanical strain frequency, the generated output is also proportional to the applied stress amplitude. The first NG loaded in bending mode can generate a maximum voltage of 270 mV. By connecting two devices in series/parallel, the voltage/current value could be multiplied by two. The second NG which was biased in compression mode using a shaker controlled by a force sensor, can generate a potential of about 7 V under 3.6 N applied force.

  6. Três biografias quinhentistas da Rainha Santa Isabel

    Directory of Open Access Journals (Sweden)

    Helena Costa Toipa

    2016-12-01

    Full Text Available Dando continuidade aos esforços de canonização de D. Isabel de Aragão, D. João III obteve do Papa, em 1556, a autorização para alargar o culto da já beata D. Isabel a todo o reino. Solicitou, então, aos responsáveis dos mosteiros portugueses, nomeadamente à abadessa do mosteiro de Santa Clara, a composição de uma biografia da rainha, a partir de documentos existentes nesse mosteiro. Surgiram, então, três biografias, todas inspiradas nos referidos documentos: De Vita et Moribus Beatae Elisabethae Lusitaniae Reginae do padre jesuíta Pedro João Perpinhão; Vida e milagres da gloriosa Raynha sancta Ysabel, molher do catholico Rey dom Dinis sexto de Portugal, editada pelos mordomos da Confraria da Rainha Santa Isabel, e “ Vida da Bemaventurada sancta Isabel Raynha de Portugal”, de Frei Marcos de Lisboa, inclusa na Segunda Parte das suas Chronicas da Ordemdos Frades Menores.

  7. The Significance of the Trömner Sign in Cervical Spondylotic Myelopathy Patient.

    Science.gov (United States)

    Chaiyamongkol, Weera; Laohawiriyakamol, Teeranan; Tangtrakulwanich, Boonsin; Tanutit, Pramot; Bintachitt, Piyawat; Siribumrungwong, Koopong

    2017-11-01

    This study is a diagnostic analysis. To investigate the diagnostic accuracy of Trömner sign in cervical spondylotic myelopathy (CSM), and how its presence correlates with the severity of myelopathy. A clinical presentation of myelopathy corresponding with image findings is a current standard to diagnose CSM. Trömner sign is an alternative of well-known Hoffmann sign to detect CSM. Little is known about its diagnostic accuracy and how its presence correlates with the severity of CSM. Consecutive patients with clinical diagnosis of CSM and other cervical spondylosis-related problems were enrolled in either CSM group, cervical spondylotic radiculopathy group, or axial pain group. Normal volunteers and patients without spine-related issues were used as a control. All participants were examined for the presence of myelopathic signs. Magnetic resonance imaging studies of all participants were reviewed by a radiologist. There were 85 participants included in the study. Diagnostic sensitivity was 76%, 94%, 76%, and 36% for Hoffmann sign, Trömner sign, inverted radial reflex, and Babinski sign, respectively. Trömner sign had relatively high sensitivity (95%) despite of mild degree of myelopathy. Negative predictive value was 60%, 85%, 59%, and 38% for Hoffmann sign, Trömner sign, inverted radial reflex, and Babinski sign, respectively. There were 63%-71% of patients in either axial pain group or cervical spondylotic radiculopathy group had positive Trömner sign. Most of CSM patients with cord signal changed had positive myelopathic sign. Regarding CSM patient without cord signal change, most of tests were negative except Trömner sign. High sensitivity (94%) and relatively high negative predictive value (85%) for Trömner sign indicate the usefulness of Trömner sign in ruling out CSM. High incidence of positive Trömner sign in presymptomatic cervical cord compression patients suggests Trömner sign could have a useful role in early detection of presymptomatic

  8. Spectroscopic markers of the TR quaternary transition in human hemoglobin.

    Science.gov (United States)

    Schirò, Giorgio; Cammarata, Marco; Levantino, Matteo; Cupane, Antonio

    2005-04-01

    In this work, we use a sol-gel protocol to trap and compare the R and T quaternary states of both the deoxygenated (deoxyHb) and carbonmonoxide (HbCO) derivatives of human hemoglobin. The near infrared optical absorption band III and the infrared CO stretching band are used to detect the effect of quaternary structure on the spectral properties of deoxyHb and HbCO; comparison with myoglobin allows for an assessment of tertiary and quaternary contributions to the measured band shifts. The RT transition is shown to cause a blue shift of the band III by approximately 35 cm(-1) for deoxyHb and a red shift of the CO stretching band by only approximately 0.3 cm(-1) for HbCO. This clearly shows that quaternary structure changes are transmitted to the heme pocket and that effects on deoxyHb are much larger than on HbCO, at least as far as the band energies are concerned. Experiments performed in the ample temperature interval of 300-10K show that the above quaternary structure effects are "static" and do not influence the dynamic properties of the heme pocket, at least as probed by the temperature dependence of band III and of the CO stretching band. The availability of quaternary structure sensitive spectroscopic markers and the quantitative measurement of the quaternary structure contribution to band shifts will be of considerable help in the analysis of flash-photolysis experiments on hemoglobin. Moreover, it will enable one to characterize the dynamic properties of functionally relevant hemoglobin intermediates and to study the kinetics of both the T-->R and R-->T quaternary transitions through time-resolved spectroscopy.

  9. The design of an asynchronous Tiny RISC TM/TR4101 microprocessor core

    DEFF Research Database (Denmark)

    Christensen, Kåre Tais; Jensen, P.; Korger, P.

    1998-01-01

    This paper presents the design of an asynchronous version of the TR4101 embedded microprocessor core developed by LSI Logic Inc. The asynchronous processor, called ARISC, was designed using the same CAD tools and the same standard cell library that was used to implement the TR4101. The paper...

  10. Samlingsdetaljers indflydelse på fugtniveauet i træfacader

    DEFF Research Database (Denmark)

    Nicolajsen, Asta; Hansen, Morten Hjorslev

    Fugtophobningen i en række træfacadeelementer med forskellige konstruktionsopbygninger med eller uden fejl i samlingerne er bestemt under laboratorieforhold. Rapporten dokumenterer, at fejl i samlinger mellem træfacadeelementer medfører højere fugtindhold i konstruktionstræet, end når samlingerne...

  11. Fugtforhold i træfacader med letbeton bagvægge

    DEFF Research Database (Denmark)

    Dela Stang, B.

    Denne rapport beskriver, hvilke faktorer der har indflydelse på ophobningen af fugt i lette træfacader med bagvægge af letbeton. Såvel laboratorieforsøg som inspektion af eksisterende bygninger viser, at bagvægge af letbeton kombineret med lette træfacader giver en konstruktion, som er yderst føl...

  12. The Orphan Nuclear Receptor TR4 Is a Vitamin A-activated Nuclear Receptor

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, X. Edward; Suino-Powell, Kelly M.; Xu, Yong; Chan, Cee-Wah; Tanabe, Osamu; Kruse, Schoen W.; Reynolds, Ross; Engel, James Douglas; Xu, H. Eric (Michigan-Med); (Van Andel)

    2015-11-30

    Testicular receptors 2 and 4 (TR2/4) constitute a subgroup of orphan nuclear receptors that play important roles in spermatogenesis, lipid and lipoprotein regulation, and the development of the central nervous system. Currently, little is known about the structural features and the ligand regulation of these receptors. Here we report the crystal structure of the ligand-free TR4 ligand binding domain, which reveals an autorepressed conformation. The ligand binding pocket of TR4 is filled by the C-terminal half of helix 10, and the cofactor binding site is occupied by the AF-2 helix, thus preventing ligand-independent activation of the receptor. However, TR4 exhibits constitutive transcriptional activity on multiple promoters, which can be further potentiated by nuclear receptor coactivators. Mutations designed to disrupt cofactor binding, dimerization, or ligand binding substantially reduce the transcriptional activity of this receptor. Importantly, both retinol and retinoic acid are able to promote TR4 to recruit coactivators and to activate a TR4-regulated reporter. These findings demonstrate that TR4 is a ligand-regulated nuclear receptor and suggest that retinoids might have a much wider regulatory role via activation of orphan receptors such as TR4.

  13. Xylan oligosaccharides and cellobiohydrolase I (TrCeI7A) interaction and effect on activity

    DEFF Research Database (Denmark)

    Baumann, Martin Johannes; Borch, Kim; Westh, Peter

    2011-01-01

    and an enzyme variant without the cellulose-binding domain (CBM). Results We studied the binding of XOSs to TrCel7A by isothermal titration calorimetry. We found that XOSs bind to TrCel7A and that the affinity increases commensurate with XOS length. The CBM, on the other hand, did not affect the affinity...

  14. The anti-inflammatory effect of TR6 on LPS-induced mastitis in mice.

    Science.gov (United States)

    Hu, Xiaoyu; Fu, Yunhe; Tian, Yuan; Zhang, Zecai; Zhang, Wenlong; Gao, Xuejiao; Lu, Xiaojie; Cao, Yongguo; Zhang, Naisheng

    2016-01-01

    [TRIAP]-derived decoy peptides have anti-inflammatory properties. In this study, we synthesized a TRIAP-derived decoy peptide (TR6) containing, the N-terminal portion of the third helical region of the [TIRAP] TIR domain (sequence "N"-RQIKIWFQNRRMKWK and -KPGFLRDPWCKYQML-"C"). We evaluated the effects of TR6 on lipopolysaccharide-induced mastitis in mice. In vivo, the mastitis model was induced by LPS administration for 24h, and TR6 treatment was initiated 1h before or after induction of LPS. In vitro, primary mouse mammary epithelial cells and neutrophils were used to investigate the effects of TR6 on LPS-induced inflammatory responses. The results showed that TR6 significantly inhibited mammary gland hisopathologic changes, MPO activity, and LPS-induced production of TNF-α, IL-1β and IL-6. In vitro, TR6 significantly inhibited LPS-induced TNF-α and IL-6 production and phosphorylation of NF-κB and MAPKs. In conclusion, this study demonstrated that the anti-inflammatory effect of TR6 against LPS-induced mastitis may be due to its ability to inhibit TLR4-mediated NF-κB and MAPK signaling pathways. TR6 may be a promising therapeutic reagent for mastitis treatment. Copyright © 2015. Published by Elsevier B.V.

  15. Design considerations for high-power VHF radar transceivers: T/R switch design

    Science.gov (United States)

    Ecklund, W. L.

    1983-01-01

    The transceiver (TR) switch developed at NOAA's Aeronomy Laboratory for use in their 50 kW peak power, 50 MHz transmitter is described. The switch mounts inside the transmitter chassis and was designed to be compact while retaining the ability to handle well over 50 kW peak power at average power levels up to 2 kW. The TR switch is a conventional TR/ATR design with equivalent /4 transmission line sections constructed of lumped constant coils and transmitting capacitors in ''Tee' sections. Two TR sections are placed in series to achieve adequate receiver protection. The switch is set into the ''transmit' mode by forward biasing the 3 pin diodes to about 1.2 amperes each. The receive mode is achieved by back biasing the diodes to -15 volts. A directional coupler is also incorporated into the TR switch box to provide a convenient monitor point for forward and reflected transmitter power.

  16. TR4 nuclear receptor suppresses HCC cell invasion via downregulating the EphA2 expression.

    Science.gov (United States)

    Jin, Ren'an; Lin, Hui; Li, Gonghui; Xu, Junjie; Shi, Liang; Chang, Chawnshang; Cai, Xiujun

    2018-02-15

    Early studies indicated that testicular nuclear receptor 4 (TR 4 ) could function as a suppressor in the transcriptional regulation of the HBV core gene expression, which might then influence the development of hepatocellular carcinoma (HCC). The direct linkage between TR 4 and HCC progression, however, remained unclear. Here, via a human clinical sample survey, we found that 13 of the 18 HCC patients studied had lower TR 4 expression in metastatic lesions than in matched primary HCC lesions, suggesting that TR 4 may play a negative role in HCC metastasis. Results from in vitro cell migration/invasion studied confirmed that TR 4 could suppress HCC cell migration/invasion. Mechanism dissection revealed that TR 4 might function through downregulating ephrin type-A receptor 2 (EphA2) expression at the transcriptional level via direct binding to the TR 4 REs located on the 5' promoter of EphA2 to suppress HCC cell migration/invasion. Targeting the EphA2 via EphA2-siRNA partially reversed the enhanced HCC cell migration/invasion with confirmed TR 4 knockdown. Notably, results from preclinical studies using in vivo mouse model with orthotopic xenograft of HCC LM3 cells also confirmed the in vitro findings. Taking these findings together, preclinical studies using multiple in vitro HCC cell lines and an in vivo mouse model all led to the conclusion that TR 4 may function as a suppressor of HCC metastasis and that targeting this newly identified TR 4 -EphA2 signaling may improve our ability to suppress HCC metastasis.

  17. Proper orthogonal decomposition-based spatial refinement of TR-PIV realizations using high-resolution non-TR-PIV measurements

    Science.gov (United States)

    He, Chuangxin; Liu, Yingzheng

    2017-07-01

    A proper orthogonal decomposition (POD)-based spatial refinement approach is proposed to increase the resolution of time-resolved particle image velocimetry (TR-PIV) realizations. POD analysis of the high-resolution non-TR-PIV measurements is used to construct the high-resolution POD modes, and the TR-PIV instantaneous realization with relatively low spatial resolution is cross-projected onto the POD modes to obtain the time-varying mode coefficients. Subsequently, the high-resolution time-resolved flow fields, which inherit the information of the superimposed multi-scale structures from the non-TR-PIV measurements, are reconstructed using the linear combination of the cross-projected mode coefficients and the corresponding high-resolution POD modes. Two main sources of error in the novel strategy are discussed: the cross-projected reconstruction of the instantaneous fields, which are excluded in the determination of the high-resolution POD modes, and the interpolation that maps the high-resolution POD modes onto the coarse grid in the cross-projection process when estimating the mode coefficients. To evaluate the method, the flow fields of a free round jet at Reynolds number Re = 3000 are separately measured in the same field-of-view region using non-TR-PIV and TR-PIV setups with a spatial resolution ratio of 42:1. The high- and low-resolution realizations of the instantaneous flow fields measured by the non-TR-PIV setup are determined by applying fine (32 × 32 pixels) and coarse (128 × 128 pixels) interrogation windows, respectively, to ensure accurate fine-to-coarse mapping of the POD modes and for use as a reference to assess the refinement accuracy. This evaluation shows that the combination of these two error sources can be minimized when the POD-sample size (the number of snapshots employed in the decomposition) and the number of POD modes for refinement are optimized. Finally, application of the present method to TR-PIV data shows that the high

  18. TR32DB - Management of Research Data in a Collaborative, Interdisciplinary Research Project

    Science.gov (United States)

    Curdt, Constanze; Hoffmeister, Dirk; Waldhoff, Guido; Lang, Ulrich; Bareth, Georg

    2015-04-01

    The management of research data in a well-structured and documented manner is essential in the context of collaborative, interdisciplinary research environments (e.g. across various institutions). Consequently, set-up and use of a research data management (RDM) system like a data repository or project database is necessary. These systems should accompany and support scientists during the entire research life cycle (e.g. data collection, documentation, storage, archiving, sharing, publishing) and operate cross-disciplinary in interdisciplinary research projects. Challenges and problems of RDM are well-know. Consequently, the set-up of a user-friendly, well-documented, sustainable RDM system is essential, as well as user support and further assistance. In the framework of the Transregio Collaborative Research Centre 32 'Patterns in Soil-Vegetation-Atmosphere Systems: Monitoring, Modelling, and Data Assimilation' (CRC/TR32), funded by the German Research Foundation (DFG), a RDM system was self-designed and implemented. The CRC/TR32 project database (TR32DB, www.tr32db.de) is operating online since early 2008. The TR32DB handles all data, which are created by the involved project participants from several institutions (e.g. Universities of Cologne, Bonn, Aachen, and the Research Centre Jülich) and research fields (e.g. soil and plant sciences, hydrology, geography, geophysics, meteorology, remote sensing). Very heterogeneous research data are considered, which are resulting from field measurement campaigns, meteorological monitoring, remote sensing, laboratory studies and modelling approaches. Furthermore, outcomes like publications, conference contributions, PhD reports and corresponding images are regarded. The TR32DB project database is set-up in cooperation with the Regional Computing Centre of the University of Cologne (RRZK) and also located in this hardware environment. The TR32DB system architecture is composed of three main components: (i) a file-based data

  19. TR-BREATH: Time-Reversal Breathing Rate Estimation and Detection.

    Science.gov (United States)

    Chen, Chen; Han, Yi; Chen, Yan; Lai, Hung-Quoc; Zhang, Feng; Wang, Beibei; Liu, K J Ray

    2018-03-01

    In this paper, we introduce TR-BREATH, a time-reversal (TR)-based contact-free breathing monitoring system. It is capable of breathing detection and multiperson breathing rate estimation within a short period of time using off-the-shelf WiFi devices. The proposed system exploits the channel state information (CSI) to capture the miniature variations in the environment caused by breathing. To magnify the CSI variations, TR-BREATH projects CSIs into the TR resonating strength (TRRS) feature space and analyzes the TRRS by the Root-MUSIC and affinity propagation algorithms. Extensive experiment results indoor demonstrate a perfect detection rate of breathing. With only 10 s of measurement, a mean accuracy of can be obtained for single-person breathing rate estimation under the non-line-of-sight (NLOS) scenario. Furthermore, it achieves a mean accuracy of in breathing rate estimation for a dozen people under the line-of-sight scenario and a mean accuracy of in breathing rate estimation of nine people under the NLOS scenario, both with 63 s of measurement. Moreover, TR-BREATH can estimate the number of people with an error around 1. We also demonstrate that TR-BREATH is robust against packet loss and motions. With the prevailing of WiFi, TR-BREATH can be applied for in-home and real-time breathing monitoring.

  20. TR146 cells grown on filters as a model of human buccal epithelium

    DEFF Research Database (Denmark)

    Nielsen, H M; Rassing, M R; Nielsen, Hanne Mørck

    2000-01-01

    and porcine buccal mucosa. Further, the permeability rates of ten beta-adrenoceptor antagonists (acebutolol, alprenolol, atenolol, labetalol, metoprolol, oxprenolol, pindolol, propranolol, timolol and tertatolol) across the TR146 cell culture model and porcine buccal mucosa were related to their lipophilicity...... x 10(-6) cm/s (metoprolol). For propranolol the cellular permeability value (P(c)) was lower than expected, probably due to accumulation in the TR146 cell layers. Limited correlation of permeability with k' was observed both for the TR146 cell culture model and the porcine buccal mucosa, although...

  1. A G-band 160 GHz T/R Module Concept for Planetary Landing Radar

    Science.gov (United States)

    Samoska, Lorene; Kangaslahti, Pekka; Pukala, David; Sadowy, Gregory; Pollard, Brian; Hodges, Richard

    2006-01-01

    In this work, the concept of a G-band transmit/receive (T/R) module centered at 160 GHz was discussed. The design makes use of state-of-the-art G-band MMIC low noise amplifiers and power amplifiers, and a high speed SPDT InGaAs PIN diode switch. The paper reports on the designs, chip results, and the integration concept for a 160 GHz T/R module. The G-band T/R module has applications toward precision altimetry and velocimetry measurements in landing radar, such as in future planetary landers on the surface of Mars

  2. A case report and brief literature review of Klippel-Trénaunay syndrome

    Directory of Open Access Journals (Sweden)

    Choudhary MG

    2012-05-01

    Full Text Available Madan Gopal Choudhary, Zia Ul Haq, Ram Narayan Sehra, Chandra Kumar ChaharDepartment of Paediatrics, Sardar Patel Medical College and P.B.M Hospital, Rajasthan, IndiaAbstract: Klippel-Trénaunay syndrome is a rare disorder characterized by the triad of vascular malformations, venous varicosities, and bone and soft-tissue hypertrophy. We present a case of Klippel-Trénaunay syndrome with limb hypertrophy, port-wine stains, angiokeratoma, and venous varicosities in the limbs.Keywords: Klippel-Trénaunay syndrome, sporadic, venous varicosities, port-wine stain, angiokeratoma

  3. Turkey's regulatory plans for high enriched to low enriched conversion of TR-2 reactor core

    International Nuclear Information System (INIS)

    Guelol Oezdere, Oya

    2003-01-01

    Turkey is a developing country and has three nuclear facilities two of which are research reactors and one pilot fuel production plant. One of the two research reactors is TR-2 which is located in Cekmece site in Istanbul. TR-2 Reactor's core is composed of both high enriched and low enriched fuel and from high enriched to low enriched core conversion project will take place in year 2005. This paper presents the plans for drafting regulations on the safety analysis report updates for high enriched to low enriched core conversion of TR-2 reactor, the present regulatory structure of Turkey and licensing activities of nuclear facilities. (author)

  4. Trženjski splet v ekonomski teoriji ali "chamberlinovih" 4p

    OpenAIRE

    Lah, Marko

    2014-01-01

    Prispevek obravnava korenine trženjske teorije 4P oziroma njenih posameznih elementov v delu ekonomista Edwarda H. Chamberlina. Trženjsko videnje Chamberlinove teorije monopolistične konkurence, kar je jedrnato prikazano s "Chamberlinovo" tabelo 4P - pokaže, da je Chamberlina mogoče videti kot začetnika teorije 4P. Takšen pristop izpostavlja pomen Chamberlinove kratkoročne analize oziroma - v trženjskem jeziku - ohranjanja kratkoročnih konkurenčnih prednosti podjetja, ki nastajajo zaradi učin...

  5. Sucesos raros en Ingeniería de Tráfico

    OpenAIRE

    Soler Flores, Francisco José; Olivas Varela, José Ángel; López González, M. Dolores

    2014-01-01

    La Ingeniería de Tráfico, como rama de la ingeniería del transporte y de la ingeniería civil trata la planificación, diseño y operación de tráfico en las calles, carreteras y autopistas, sus redes, infraestructuras, tierras colindantes y su relación con los diferentes medios de transporte para conseguir una movilidad segura, eficiente y conveniente tanto de personas como de mercancías. La ingeniería de tráfico estudia los accidentes de tráfico, éstos por ser sucesos de muy baja probabilida...

  6. Kinematic MRI using short TR single shot fast spin echo (SSFSE) in evaluating swallowing

    International Nuclear Information System (INIS)

    Isogai, Satoshi; Takehara, Yasuo; Isoda, Haruo; Kodaira, Nami; Masunaga, Hatsuko; Ozawa, Fukujirou; Kaneko, Masao; Nozaki, Atsushi; Kabasawa, Hiroyuki

    1999-01-01

    The utility of short TR single shot fast spin echo (SSFSE) MR imaging for evaluating swallowing was determined. Five healthy volunteers underwent kinematic MR imaging of swallowing with a 1.5 T MR scanner using the short TR (300 ms) SSFSE sequence. Twenty phases of sagittal sections were acquired within 6 sec, where the temporal resolution was 300 ms. For oral contrast medium, we used prune yogurt juice with Fe added. The image contrast of short TR SSFSE was found to be somewhere like that of T1-weighted images. In all cases, both the buccal and pharyngeal stages of swallowing were successfully depicted. The Fe-added prune yogurt juice performed as a positive contrast medium and helped determine anatomical structures in the buccal stage. Short TR (300 ms) SSFSE was useful in evaluating swallowing. The combined use of Fe-added prune yogurt juice was helpful in enhancing the surface of the oropharynx. (author)

  7. TR146 cells grown on filters as a model of human buccal epithelium

    DEFF Research Database (Denmark)

    Mørck Nielsen, H; Rømer Rassing, M; Nielsen, Hanne Mørck

    2000-01-01

    The objective of the present study was to characterise the TR146 cell culture model as an in vitro model of human buccal mucosa with respect to the enzyme activity in the tissues. For this purpose, the contents of aminopeptidase, carboxypeptidase and esterase in homogenate supernatants of the TR146...... cell culture model, and human and porcine buccal epithelium were compared. The esterase activity in the intact cell culture model and in the porcine buccal mucosa was compared. Further, the TR146 cell culture model was used to study the permeability rate and metabolism of leu-enkephalin. The activity...... (3.73+/-0.53 nmol/min per mg protein), whereas the level of esterase activity was significantly higher (223.39+/-69.82 nmol/min per mg protein). In the TR146 cell culture model, the apical esterase activity was found significantly higher than the basal activity, and found comparable to the porcine...

  8. Flexible T/R Modules for Large-Aperture, Space-Based SAR Project

    Data.gov (United States)

    National Aeronautics and Space Administration — SI2 Technologies, Inc (SI2) proposes to develop membrane compatible transmit/receive (T/R) modules for flexible, space-deployable synthetic aperture radar (SAR)...

  9. Hüpertekst vs trükitekst / Kärt Matiisen

    Index Scriptorium Estoniae

    Matiisen, Kärt

    2003-01-01

    Eksperimendist Kose Gümnaasiumi 8. klasside õpilaste hulgas tõestamaks arvutiõppe eeliseid. Ilmnes, et 24 tundi hiljem mäletavad hüperteksti lugenud õpilased seda paremini kui klassikalist trükiteksti

  10. Herpesvirus telomerase RNA (vTR with a mutated template sequence abrogates herpesvirus-induced lymphomagenesis.

    Directory of Open Access Journals (Sweden)

    Benedikt B Kaufer

    2011-10-01

    Full Text Available Telomerase reverse transcriptase (TERT and telomerase RNA (TR represent the enzymatically active components of telomerase. In the complex, TR provides the template for the addition of telomeric repeats to telomeres, a protective structure at the end of linear chromosomes. Human TR with a mutation in the template region has been previously shown to inhibit proliferation of cancer cells in vitro. In this report, we examined the effects of a mutation in the template of a virus encoded TR (vTR on herpesvirus-induced tumorigenesis in vivo. For this purpose, we used the oncogenic avian herpesvirus Marek's disease virus (MDV as a natural virus-host model for lymphomagenesis. We generated recombinant MDV in which the vTR template sequence was mutated from AATCCCAATC to ATATATATAT (vAU5 by two-step Red-mediated mutagenesis. Recombinant viruses harboring the template mutation replicated with kinetics comparable to parental and revertant viruses in vitro. However, mutation of the vTR template sequence completely abrogated virus-induced tumor formation in vivo, although the virus was able to undergo low-level lytic replication. To confirm that the absence of tumors was dependent on the presence of mutant vTR in the telomerase complex, a second mutation was introduced in vAU5 that targeted the P6.1 stem loop, a conserved region essential for vTR-TERT interaction. Absence of vTR-AU5 from the telomerase complex restored virus-induced lymphoma formation. To test if the attenuated vAU5 could be used as an effective vaccine against MDV, we performed vaccination-challenge studies and determined that vaccination with vAU5 completely protected chickens from lethal challenge with highly virulent MDV. Taken together, our results demonstrate 1 that mutation of the vTR template sequence can completely abrogate virus-induced tumorigenesis, likely by the inhibition of cancer cell proliferation, and 2 that this strategy could be used to generate novel vaccine candidates

  11. Antimicrobial and insect antifeedant activities of some Tröger’s bases

    Directory of Open Access Journals (Sweden)

    G. Thirunarayanan

    2017-02-01

    Full Text Available A series of substituted Tröger’s bases (2,8-dimethyl-6H, 12H- 5,11-methanodibenzo[b, f][1,5] diazocines have been synthesized and resolved. These bases are characterized by their physical constants, micro analyses, IR, NMR and mass spectral data. The antimicrobial and insect antifeedant activities of these Tröger’s bases have been screened.

  12. Nonlinear elastic wave spectroscopy in symbiosis with time reversal for localization of defects: TR-NEWS

    Czech Academy of Sciences Publication Activity Database

    Dos Santos, S.; Vejvodová, Šárka; Převorovský, Zdeněk

    2009-01-01

    Roč. 19, č. 2 (2009), s. 14-14 ISSN 1213-3825. [NDT in PROGRESS. 12.11.2009-14.11.2009, Praha] R&D Projects: GA ČR GA106/07/1393; GA MPO(CZ) FR-TI1/274 Institutional research plan: CEZ:AV0Z20760514 Keywords : nonlinear elastic wave spectroscopy (NEWS) * ESAM * time reversal (TR) * TR-NEWS imaging * tomography * DORT Subject RIV: BI - Acoustics

  13. A case report and brief literature review of Klippel-Trénaunay syndrome

    OpenAIRE

    Choudhary MG; Haq ZU; Sehra RN; Chahar CK

    2012-01-01

    Madan Gopal Choudhary, Zia Ul Haq, Ram Narayan Sehra, Chandra Kumar ChaharDepartment of Paediatrics, Sardar Patel Medical College and P.B.M Hospital, Rajasthan, IndiaAbstract: Klippel-Trénaunay syndrome is a rare disorder characterized by the triad of vascular malformations, venous varicosities, and bone and soft-tissue hypertrophy. We present a case of Klippel-Trénaunay syndrome with limb hypertrophy, port-wine stains, angiokeratoma, and venous varicosities in the limbs...

  14. Kirjastamine 21. sajandil - trüki oma raamat ise / Rivo Sarapik, Andres Kütt, Stanislav Sinyagin

    Index Scriptorium Estoniae

    Sarapik, Rivo, 1981-

    2008-01-01

    Väikesetiraa̓iliste trükiste kirjastamise etappidest ja soovitusi trükifirmade valikul internetis ning erinevate inimeste kogemusi fotoraamatu või fotoajakirja trükkimisel, kasutades Blurb.com või Lulu.com teenust. Kuni väljatrükini on teenus valdavalt tasuta

  15. Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology.

    Directory of Open Access Journals (Sweden)

    Marcela Montes de Oca

    2016-01-01

    Full Text Available Tumor necrosis factor (TNF is critical for controlling many intracellular infections, but can also contribute to inflammation. It can promote the destruction of important cell populations and trigger dramatic tissue remodeling following establishment of chronic disease. Therefore, a better understanding of TNF regulation is needed to allow pathogen control without causing or exacerbating disease. IL-10 is an important regulatory cytokine with broad activities, including the suppression of inflammation. IL-10 is produced by different immune cells; however, its regulation and function appears to be cell-specific and context-dependent. Recently, IL-10 produced by Th1 (Tr1 cells was shown to protect host tissues from inflammation induced following infection. Here, we identify a novel pathway of TNF regulation by IL-10 from Tr1 cells during parasitic infection. We report elevated Blimp-1 mRNA levels in CD4+ T cells from visceral leishmaniasis (VL patients, and demonstrate IL-12 was essential for Blimp-1 expression and Tr1 cell development in experimental VL. Critically, we show Blimp-1-dependent IL-10 production by Tr1 cells prevents tissue damage caused by IFNγ-dependent TNF production. Therefore, we identify Blimp-1-dependent IL-10 produced by Tr1 cells as a key regulator of TNF-mediated pathology and identify Tr1 cells as potential therapeutic tools to control inflammation.

  16. Synthesis and structural characterization of the Zintl phases Na{sub 3}Ca{sub 3}TrPn{sub 4}, Na{sub 3}Sr{sub 3}TrPn{sub 4}, and Na{sub 3}Eu{sub 3}TrPn{sub 4} (Tr=Al, Ga, In; Pn=P, As, Sb)

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yi [Department of Chemistry & Biochemistry, University of Delaware, 304A Drake Hall, Newark, DE 19716 (United States); Suen, Nian-Tzu [Department of Chemistry & Biochemistry, University of Delaware, 304A Drake Hall, Newark, DE 19716 (United States); College of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002 (China); Kunene, Thabiso; Stoyko, Stanislav [Department of Chemistry & Biochemistry, University of Delaware, 304A Drake Hall, Newark, DE 19716 (United States); Bobev, Svilen, E-mail: bobev@udel.edu [Department of Chemistry & Biochemistry, University of Delaware, 304A Drake Hall, Newark, DE 19716 (United States)

    2017-05-15

    15 new quaternary Zintl phases have been synthesized by solid-state reactions from the respective elements, and their structures have been determined by single-crystal X-ray diffraction. Na{sub 3}E{sub 3}TrPn{sub 4} (E=Ca, Sr, Eu; Tr=Al, Ga, In; Pn=P, As, Sb) crystallize in the hexagonal crystal system with the non-centrosymmetric space group P6{sub 3}mc (No. 186). The structure represents a variant of the K{sub 6}HgS{sub 4} structure type (Pearson index hP22) and features [TrPn{sub 4}]{sup 9–} tetrahedral units, surrounded by Na{sup +} and Ca{sup 2+}, Sr{sup 2+}, Eu{sup 2+} cations. The nominal formula rationalization [Na{sup +}]{sub 3}[E{sup 2+}]{sub 3}[TrPn{sub 4}]{sup 9–} follows the octet rule, suggesting closed-shell configurations for all atoms and intrinsic semiconducting behavior. However, structure refinements for several members hint at disorder and mixing of cations that potentially counteract the optimal valence electron count. - Graphical abstract: The hexagonal, non-centrosymmetric structure of Na{sub 3}E{sub 3}TrPn{sub 4} (E=Ca, Sr, Eu; Tr=Al, Ga, In; Pn=P, As, Sb) features [TrPn{sub 4}]{sup 9–} tetrahedral units, surrounded by Na{sup +} and Ca{sup 2+}, Sr{sup 2+}, Eu{sup 2+} cations. - Highlights: • 15 quaternary phosphides, arsenides, and antimonides are synthesized and structurally characterized. • The structure is a variant of the hexagonal K{sub 6}HgS{sub 4}-type, with distinctive pattern for the cations. • Occupational and/or positional disorder of yet unknown origin exists for some members of the series.

  17. Nano-structured variable capacitor based on P(VDF-TrFE) copolymer and carbon nanotubes

    Science.gov (United States)

    Lakbita, I.; El-Hami, K.

    2018-02-01

    A newly organic capacitor was conceived with a variable capacitance using the inverse piezoelectric effect. The device consists of two parallel plates of carbon nanotubes (CNTs), known for their large surface area, high sensitivity and high electric conductivity, separated by a thin film of a dielectric layer of Polyinylidene fluoride and trifluoroehtylene (P(VDF-TrFE)) promising material for piezoelectric and ferroelectric properties. The obtained architecture is the CNT/PVDF-TrFE/CNT capacitor device. In this study, an ultra-thin film of P(VDF-TrFE) (54/46) with thickness of 20 nm was elaborated on highly oriented pyrolytic graphite (HOPG) by spin-coating. The morphology of the ultra-thin film and the mechanical behavior of CNT/P(VDF-TrFE)/CNT system were studied using the atomic force microscopy (AFM) combined with a lock-in amplifier in contact mode. All changes in applied voltage induce a change in thin film thickness according to the inverse piezoelectric effect that affect, consequently the capacitance. The results showed that the ratio of capacitance change ΔC to initial capacitance C0 is ΔC/C0=5%. This value is sufficient to use P(VDF-TrFE) as variable organic capacitor.

  18. Estimation of Theaflavins (TF) and Thearubigins (TR) Ratio in Black Tea Liquor Using Electronic Vision System

    Science.gov (United States)

    Akuli, Amitava; Pal, Abhra; Ghosh, Arunangshu; Bhattacharyya, Nabarun; Bandhopadhyya, Rajib; Tamuly, Pradip; Gogoi, Nagen

    2011-09-01

    Quality of black tea is generally assessed using organoleptic tests by professional tea tasters. They determine the quality of black tea based on its appearance (in dry condition and during liquor formation), aroma and taste. Variation in the above parameters is actually contributed by a number of chemical compounds like, Theaflavins (TF), Thearubigins (TR), Caffeine, Linalool, Geraniol etc. Among the above, TF and TR are the most important chemical compounds, which actually contribute to the formation of taste, colour and brightness in tea liquor. Estimation of TF and TR in black tea is generally done using a spectrophotometer instrument. But, the analysis technique undergoes a rigorous and time consuming effort for sample preparation; also the operation of costly spectrophotometer requires expert manpower. To overcome above problems an Electronic Vision System based on digital image processing technique has been developed. The system is faster, low cost, repeatable and can estimate the amount of TF and TR ratio for black tea liquor with accuracy. The data analysis is done using Principal Component Analysis (PCA), Multiple Linear Regression (MLR) and Multiple Discriminate Analysis (MDA). A correlation has been established between colour of tea liquor images and TF, TR ratio. This paper describes the newly developed E-Vision system, experimental methods, data analysis algorithms and finally, the performance of the E-Vision System as compared to the results of traditional spectrophotometer.

  19. Regulation of mitosis-meiosis transition by the ubiquitin ligase β-TrCP in male germ cells.

    Science.gov (United States)

    Nakagawa, Tadashi; Zhang, Teng; Kushi, Ryo; Nakano, Seiji; Endo, Takahiro; Nakagawa, Makiko; Yanagihara, Noriko; Zarkower, David; Nakayama, Keiko

    2017-11-15

    The mitosis-meiosis transition is essential for spermatogenesis. Specific and timely downregulation of the transcription factor DMRT1, and consequent induction of Stra8 expression, is required for this process in mammals, but the molecular mechanism has remained unclear. Here, we show that β-TrCP, the substrate recognition component of an E3 ubiquitin ligase complex, targets DMRT1 for degradation and thereby controls the mitosis-meiosis transition in mouse male germ cells. Conditional inactivation of β-TrCP2 in male germ cells of β-TrCP1 knockout mice resulted in sterility due to a lack of mature sperm. The β-TrCP-deficient male germ cells did not enter meiosis, but instead underwent apoptosis. The induction of Stra8 expression was also attenuated in association with the accumulation of DMRT1 at the Stra8 promoter in β-TrCP-deficient testes. DMRT1 contains a consensus β-TrCP degron sequence that was found to bind β-TrCP. Overexpression of β-TrCP induced the ubiquitylation and degradation of DMRT1. Heterozygous deletion of Dmrt1 in β-TrCP-deficient spermatogonia increased meiotic cells with a concomitant reduction of apoptosis. Collectively, our data indicate that β-TrCP regulates the transition from mitosis to meiosis in male germ cells by targeting DMRT1 for degradation. © 2017. Published by The Company of Biologists Ltd.

  20. Building on TR-24 success. Advanced Cyclotron Systems Inc. launches a new cyclotron model

    International Nuclear Information System (INIS)

    Russell Watt; William Gyles; Alexander Zyuzin

    2015-01-01

    ACSI is designing a new 30 MeV cyclotron based on the TR-24. While minimizing changes from the proven TR-24, including maintaining the same outer dimensions, the energy of the cyclotron will be increased to 30 MeV, which will make it the most compact, non-superconducting, 30 MeV cyclotron design to date. Maximum beam current will match the TR-24 at 1 mA. With the size and footprint of a typical low energy PET cyclotron, this system will offer users a cost effective solution for a diversified facility capable of producing a wide spectrum of PET and SPECT radioisotopes for research and commercial distribution. (author)

  1. Personalidad e infracciones frecuentes de normas de tránsito

    Directory of Open Access Journals (Sweden)

    Nicolasa María Durán Palacio

    2016-01-01

    Full Text Available La Organización Mundial de la Salud (2013, alerta a los gobiernos a tomar medidas urgentes para prevenir accidentes de tránsito. Si no se intervienen, en el 2030 serán la quinta causa de muerte. Este estudio establece el perfil psicológico de conductores de vehículo infractores frecuentes de normas de tránsito, en una muestra de 295 adultos de ambos sexos. Utilizando el cuestionario factorial de personalidad 16PF-5 y una escala de creencias, conocimientos, y comportamientos sobre seguridad vial, se identificaron relaciones significativas entre conducta infractora y creencias, además de los factores de personalidad y variables específicas que predicen la propensión a las infracciones frecuentes de normas de tránsito.

  2. Luchas migrantes en contextos de tránsito migratorio, el caso del movimiento migrante centroamericano

    Directory of Open Access Journals (Sweden)

    Amarela Varela Huerta

    Full Text Available Resumen Este texto aborda un ejemplo concreto de organización de migrantes, el Movimiento Migrante Mesoamericano, que trabaja por los derechos de los migrantes en tránsito por México, de forma coordinada con organizaciones y familiares de migrantes víctimas de desaparición en su tránsito hacia Estados Unidos. Este estudio de caso es un ejemplo de luchas migrantes en contextos de tránsito, tipo específico de movimiento social que ha sido poco abordado en la literatura que piensa la acción colectiva de los migrantes. En el trabajo se analizan los actores, las prácticas, las alianzas y el contexto al que se enfrentan los activistas del movimiento en cuestión.

  3. Tráfico de drogas: uma opção entre escolhas escassas

    Directory of Open Access Journals (Sweden)

    Ana Amélia Cypreste Faria

    2011-12-01

    Full Text Available Este trabalho procura compreender os aspectos psicossociais que permeiam a adesão de pessoas ao tráfico de drogas em seu contexto histórico e econômico-social, por meio de pesquisa realizada no ambiente carcerário, onde foram recolhidas histórias de vida de pessoas envolvidas com o tráfico. Em um ambiente socioeconômico caracterizado pela precarização das relações de trabalho, pelo desemprego e pelo apelo consumista afinados com as premissas econômicas neoliberais tem-se uma situação de exclusão social e de cidadania. Assim, o tráfico se mostra como uma atividade econômica possibilitadora de inclusão, mesmo que marginal, na ordem capitalista. Uma opção a ser feita entre escolhas limitadas.

  4. Leser-Trélat sign presenting in a patient with ovarian cancer: a case report

    Directory of Open Access Journals (Sweden)

    Bölke Edwin

    2009-07-01

    Full Text Available Abstract Introduction Seborrheic keratoses are very common findings in elderly patients. However, a sudden onset and dramatic increase in the number and size of these benign lesions deserves special attention, since this may represent the Leser Trélat sign, a rare paraneoplastic cutaneous syndrome. Case presentation A 92-year-old female presented to our clinic with multiple eruptive seborrheic keratoses, which had dramatically increased in size and number over the past two years. A diagnostic work-up revealed an ovarian carcinoma. Hence, cutaneous findings in our patient were consistent with the diagnosis of the Leser-Trélat sign. Conclusion The Leser-Trélat sign may coincide with the diagnosis of occult cancer or follow or precede it by months or years. Practitioners should take cases of eruptive seborrheic keratoses seriously and perform thorough patient examinations.

  5. Tempo e Trânsito na Experiência Subjetiva de Motoristas

    OpenAIRE

    Ana Inez Oka Elvas de Lima; Sylvia Cavalcante

    2015-01-01

    Esta pesquisa investiga como são percebidos e vivenciados o tempo e a pressa no trânsito por motoristas de Fortaleza, identificando e analisando seus estados subjetivos e comportamentos associados a essa experiência. Para a coleta de dados, organizaram-se quatro grupos focais, a partir dos quais emergiram diversos elementos relacionados ao tempo e à pressa e à incidência de comportamentos inadequados no trânsito, segundo o sexo e a idade dos participantes. Para analisar os dados obtidos nas d...

  6. An introduction to TR-X: a simplified tool for standardized analysis

    Energy Technology Data Exchange (ETDEWEB)

    Johns, Russell C [Los Alamos National Laboratory; Waters, Laurie S [Los Alamos National Laboratory; Fallgren, Andrew J [Los Alamos National Laboratory; Ghoreson, Gregory G [UNIV OF TEXAS

    2010-09-09

    TR-X is a multi-platform program that provides a graphical interface to Monte Carlo N-Particle transport (MCNP) and Monte Carlo N-Particle transport eXtended (MCNPX) codes. Included in this interface are tools to reduce the tedium of input file creation, provide standardization of model creation and analysis, and expedite the execution of the created models. TR-X provides tools to make the rapid testing of multiple permutations of these models easier, while also building in standardization that allows multiple solutions to be compared.

  7. Type specimens preserved in the Trèmols and Costa herbaria (BC

    Directory of Open Access Journals (Sweden)

    Laura Gavioli

    2016-12-01

    Full Text Available The Trèmols herbarium, preserved at the Botanical Institute of Barcelona, is one of the oldest herbaria in Catalonia, largely made up of European plants collected in 19th century. The digitization of this historical collection, currently in progress, has made possible to locate nomenclatural types of various authors, acquired through exchange. In this article, we indicate two syntypes (for Fumaria caespitosa Loscos and Carex loscosii Lange, and one isolectotype (Polygala vayredae Costa in Trèmols herbarium. Additionally, we designate the lectotype of Polygala vayredae in the Costa herbarium and its isolectotype in the Vayreda herbarium.

  8. Tráfico de drogas: uma opção entre escolhas escassas

    OpenAIRE

    Faria, Ana Amélia Cypreste; Barros, Vanessa de Andrade

    2011-01-01

    Este trabalho procura compreender os aspectos psicossociais que permeiam a adesão de pessoas ao tráfico de drogas em seu contexto histórico e econômico-social, por meio de pesquisa realizada no ambiente carcerário, onde foram recolhidas histórias de vida de pessoas envolvidas com o tráfico. Em um ambiente socioeconômico caracterizado pela precarização das relações de trabalho, pelo desemprego e pelo apelo consumista afinados com as premissas econômicas neoliberais tem-se uma situação de exclu...

  9. Mito & música: o trágico no jovem Nietzsche

    OpenAIRE

    Lotério, Rafael Antônio dos Santos

    2011-01-01

    O objetivo desta dissertação é perseguir o conceito de trágico na filosofia do jovem Friedrich Wilhelm Nietzsche. Através do estudo das suas primeiras obras dedicadas à reflexão filosófica, percebemos que a ideia do “trágico” se afirma como ponto central e ganha destaque para as perspectivas de trabalho vindouro para o professor de filologia clássica que se tornaria um dos mais importantes nomes da filosofia contemporânea. Entretanto, mesmo resguardando o valor que as reflexões...

  10. Costes de operación del tráfico en la carretera

    OpenAIRE

    Cañadas Salas, Javier

    2007-01-01

    El coste de operación del tráfico en la carretera es el parámetro fundamental que se debe evaluar para la selección de rutas y para comprobar la eficiencia económica de un itinerario. El coste de operación se define como el conjunto de costes que genera el tráfico al circular por un trazado determinado. Los costes se dividen en tres subgrupos. El primer grupo se denomina coste directo, y engloba el coste por tiempo de recorrido, el coste por consumo de combustible y el coste de lo...

  11. Were the Trænadjupet and Nyk Slides multi-staged?

    Science.gov (United States)

    Allin, Joshua; Mozzato, Alessandro; Tappin, David; Talling, Peter; Hunt, James

    2016-04-01

    Submarine landslides originating from active and extinct trough mouth fans are some of the largest single mass movements evident on Earth. These landslides are capable of damaging offshore infrastructure and can also trigger far-reaching tsunamis. For these reasons understanding the timing, dynamics, and triggering mechanisms of large submarine landslides is important for regional geohazard assessment. The Trænadjupet Slide occurred 4,000 ca. years ago and originated from the Trænadjupet paleo-ice stream on the Central Norwegian margin. The Trænadjupet Slide partially buried the deposits of a previous slide originating from the same section of the Norwegian margin; the Nyk Slide, which occurred at 16,000 ca years ago. Although the Trænadjupet Slide had an estimated volume of 900 km3 and originated from a shallow water depth, it does not appear to have triggered a tsunami. This is in contrast to the comparably-sized Storegga Slide, which produced a tsunami that devastated coastal areas as far away as Scotland. The apparent absence of a tsunami suggests that the failure dynamics for the Trænadjupet slide were different to that of other large slides along the Norwegian Margin. The deposits of both the Trænadjupet and Nyk Slides consist of several blocky lobes extending out into the Lofoten Basin. The lobate morphology of the deposits may imply that both slides occurred in a number of different and possibly temporally-disparate stages. Importantly, multi-staged failures have a much lower tsunamigenic potential due to the lower initial volume displacement. These staggered failures consisting of smaller sediment volumes might explain why no contemporaneous onshore tsunami deposits are found on nearby coastlines, particularly in the case of the post-glacial Trænadjupet Slide. Here we present a new sediment core dataset collected from the previously un-sampled lobes of the Trænadjupet and Nyk Slides. These cores will help us better characterise the deposit types

  12. Space-charge-mediated anomalous ferroelectric switching in P(VDF-TrEE) polymer films

    KAUST Repository

    Hu, Weijin

    2014-11-12

    We report on the switching dynamics of P(VDF-TrEE) copolymer devices and the realization of additional substable ferroelectric states via modulation of the coupling between polarizations and space charges. The space-charge-limited current is revealed to be the dominant leakage mechanism in such organic ferroelectric devices, and electrostatic interactions due to space charges lead to the emergence of anomalous ferroelectric loops. The reliable control of ferroelectric switching in P(VDF-TrEE) copolymers opens doors toward engineering advanced organic memories with tailored switching characteristics.

  13. Rapid blockade of telomerase activity and tumor cell growth by the DPL lipofection of ribbon antisense to hTR.

    Science.gov (United States)

    Bajpai, Arun K; Park, Jeong-Hoh; Moon, Ik-Jae; Kang, Hyungu; Lee, Yun-Han; Doh, Kyung-Oh; Suh, Seong-Il; Chang, Byeong-Churl; Park, Jong-Gu

    2005-09-29

    Ribbon antisense (RiAS) to the hTR RNA, a component of the telomerase complex, was employed to inhibit telomerase activity and cancer cell growth. The antisense molecule, hTR-RiAS, combined with enhanced cellular uptake was shown to effectively inhibit telomerase activity and cause rapid cell death in various cancer cell lines. When cancer cells were treated with hTR-RiAS, the level of hTR RNA was reduced by more than 90% accompanied with reduction in telomerase activity. When checked for cancer cell viability, cancer cell lines treated with hTR-RiAS using DNA+Peptide+Lipid complex showed 70-80% growth inhibition in 3 days. The reduced cell viability was due to apoptosis as the percentage of cells exhibiting the sub-G0 arrest and DNA fragmentation increased after antisense treatment. Further, when subcutaneous tumors of a colon cancer cell line (SW480) were treated intratumorally with hTR-RiAS, tumor growth was markedly suppressed with almost total ablation of hTR RNA in the tumor tissue. Cells in the tumor tissue were also found to undergo apoptosis after hTR-RiAS treatment. These results suggest that hTR-RiAS is an effective anticancer reagent, with a potential for broad efficacy to diverse malignant tumors.

  14. Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors

    NARCIS (Netherlands)

    A. Pedroza-Gonzalez (Alexander); G. Zhou (Guoying); E. Vargas-Mendez (Ernesto); P.P.C. Boor (Patrick); S. Mancham (Shanta); C. Verhoef (Kees); W.G. Polak (Wojciech G); D.J. Grunhagen (Dirk Jan); Q. Pan (Qiuwei); H.L.A. Janssen (Harry); G.S. García-Romo (Gina); K. Biermann (Katharina); E.T.T.L. Tjwa (Eric); J.N.M. IJzermans (Jan); J. Kwekkeboom (Jaap); D. Sprengers (Dave)

    2015-01-01

    textabstractCD4+ type 1 T regulatory (Tr1) cells have a crucial role in inducing tolerance. Immune regulation by these cells is mainly mediated through the secretion of high amounts of IL-10. Several studies have suggested that this regulatory population may be involved in tumor-mediated

  15. Administrateur de la trésorerie (h/f) | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    examen annuel des procédures de gestion de la trésorerie et des processus de paiement;; Procéder au dépôt électronique de tous les documents constitutifs conformément aux normes applicables;; Préparer une analyse comptable périodique et ...

  16. Codon Optimization Leads to Functional Impairment of RD114-TR Envelope Glycoprotein

    Directory of Open Access Journals (Sweden)

    Eleonora Zucchelli

    2017-03-01

    Full Text Available Lentiviral vectors (LVs are a highly valuable tool for gene transfer currently exploited in basic, applied, and clinical studies. Their optimization is therefore very important for the field of vectorology and gene therapy. A key molecule for LV function is the envelope because it guides cell entry. The most commonly used in transiently produced LVs is the vesicular stomatitis virus glycoprotein (VSV-G envelope, whose continuous expression is, however, toxic for stable LV producer cells. In contrast, the feline endogenous retroviral RD114-TR envelope is suitable for stable LV manufacturing, being well tolerated by producer cells under constitutive expression. We have previously reported successful, transient and stable production of LVs pseudotyped with RD114-TR for good transduction of T lymphocytes and CD34+ cells. To further improve RD114-TR-pseudotyped LV cell entry by increasing envelope expression, we codon-optimized the RD114-TR open reading frame (ORF. Here we show that, despite the RD114-TRco precursor being produced at a higher level than the wild-type counterpart, it is unexpectedly not duly glycosylated, exported to the cytosol, and processed. Correct cleavage of the precursor in the functional surface and transmembrane subunits is prevented in vivo, and, consequently, the unprocessed precursor is incorporated into LVs, making them inactive.

  17. Orphan Receptor TR3/nur77 and Apoptosis in Prostate Cancer Cells

    National Research Council Canada - National Science Library

    Zhang, Xiao-kun

    2004-01-01

    .... It is overexpressed in prostate tumor and acts in the nucleus to promote tumor cell growth. In response to certain apoptotic stimuli, TR3 migrates from the nucleus to the cytoplasm where it targets mitochondria to induce cytochrome C release and apoptosis...

  18. Deploying the Win TR-20 computational engine as a web service

    Science.gov (United States)

    Despite its simplicity and limitations, the runoff curve number method remains a widely-used hydrologic modeling tool, and its use through the USDA Natural Resources Conservation Service (NRCS) computer application WinTR-20 is expected to continue for the foreseeable future. To facilitate timely up...

  19. Comparing Diagnostic Outcomes of Autism Spectrum Disorder Using "DSM-IV-TR" and "DSM-5" Criteria

    Science.gov (United States)

    Harstad, Elizabeth B.; Fogler, Jason; Sideridis, Georgios; Weas, Sarah; Mauras, Carrie; Barbaresi, William J.

    2015-01-01

    Controversy exists regarding the "DSM-5" criteria for ASD. This study tested the psychometric properties of the "DSM-5" model and determined how well it performed across different gender, IQ, and "DSM-IV-TR" sub-type, using clinically collected data on 227 subjects (median age = 3.95 years, majority had IQ > 70).…

  20. Tráfico de pessoas: uma história do conceito

    Directory of Open Access Journals (Sweden)

    Anamaria Marcon Venson

    2013-01-01

    Full Text Available A categoria tráfico de pessoas é uma proposição jurídica e não uma elaboração sociológica. Inventada no século XIX e retomada no final do século XX, tal categoria ganhou discursividade em jogo com saberes que constituíram a prostituição como um problema. A definição de tráfico disposta no atual Código Penal brasileiro se manifesta em relação necessária com a prostituição. O artigo analisa os modos como a discussão sobre o tráfico encontra lugar e efeito em jogo com a noção de que a prostituição deve ser combatida. A batalha discursiva para dizer o tráfico de pessoas e constituí-lo como um problema funciona como um reforço ao rechaço à prostituição, não protege as pessoas que se inserem voluntariamente no mercado do sexo e acaba, por vezes, sendo cúmplice de exigências internacionais de contenção migratória.

  1. “shoWing resPecT” in BiBLe TrAnsLATion

    African Journals Online (AJOL)

    ABsTrAcT. This article focuses on the way respect is shown by using 2nd person personal pronouns in languages that distinguish between you plural (you all), you honorific (polite) and you singular (familiar) forms. it discusses the likely influence of the well known rus sian synodal Translation on other translations in the ...

  2. Enhanced Piezoelectric Energy Harvesting Performance of Flexible PVDF-TrFE Bilayer Films with Graphene Oxide.

    Science.gov (United States)

    Bhavanasi, Venkateswarlu; Kumar, Vipin; Parida, Kaushik; Wang, Jiangxin; Lee, Pooi See

    2016-01-13

    Ferroelectric materials have attracted interest in recent years due to their application in energy harvesting owing to its piezoelectric nature. Ferroelectric polymers are flexible and can sustain larger strains compared to inorganic counterparts, making them attractive for harvesting energy from mechanical vibrations. Herein, we report, for the first time, the enhanced piezoelectric energy harvesting performance of the bilayer films of poled poly(vinylidene fluoride-trifluoroethylene) [PVDF-TrFE] and graphene oxide (GO). The bilayer film exhibits superior energy harvesting performance with a voltage output of 4 V and power output of 4.41 μWcm(-2) compared to poled PVDF-TrFE films alone (voltage output of 1.9 V and power output of 1.77 μWcm(-2)). The enhanced voltage and power output in the presence of GO film is due to the combined effect of electrostatic contribution from graphene oxide, residual tensile stress, enhanced Young's modulus of the bilayer films, and the presence of space charge at the interface of the PVDF-TrFE and GO films, arising from the uncompensated polarization of PVDF-TrFE. Higher Young's modulus and dielectric constant of GO led to the efficient transfer of mechanical and electrical energy.

  3. Diagnostic Distribution of eating disorders: Comparison between DSMIV- TR and DSM-5.

    Science.gov (United States)

    Serrano-Troncoso, Eduardo; Cañas, Laura; Carbonell, Xavier; Carulla, Marta; Palma, Carolina; Matalí, Josep; Dolz, Montse

    2017-01-01

    The fifth edition of Diagnostic and Statistical Manual of Mental Disorders (DSM-5) includes a significant revision of Eating Disorders (ED). The objective of this study is to compare the distribution of diagnosis of ED in adolescents according to DSM-VI-TR and DSM-5 criteria. A second objective is to study the psychopathological differences between patients with ED (based on DSM-IV-TR) and those whose diagnosis changed by applying DSM-5 criteria. One hundred and one adolescents diagnosed with ED (mean: 14.68 years; SD: 1.46) were evaluated with clinical interviews and scales for eating psychopathology, perfectionism, anxiety, and depression. Applying the DSM-5 criteria led to a significant decrease in the diagnosed cases of Eating Disorders Not Otherwise Specified (EDNOS) (from 34.7% to 23.8%; pDSM-IV-TR criteria and those newly diagnosed with AN and BN based on DSM-5 criteria. Using DSM-5 criteria for adolescents with ED leads to a significant decrease in the frequency of an EDNOS diagnosis. As similar psychopathological characteristics were observed between ED patients diagnosed based on DSM-IV-TR and those who were switched from EDNOS to AN or BN based on DSM-5, we conclude that the new criteria for ED in DSM-5 are valid for an adolescent population.

  4. Piezoelectricity enhancement of P(VDF/TrFE) by X-ray irradiation

    NARCIS (Netherlands)

    Pilet, N.; Khikhlovskyi, V.; Breemen, A.J.J.M. van; Michels, J.J.; Kemerink, M.; Gelinck, G.; Warnicke, P.; Bernard, L.

    2016-01-01

    Organic electronics is becoming more and more important because the low level of fabrication and deposition complexity even at large scale makes it a good candidate for future low cost technological product development. P(VDF-TrFE) is a co-polymer of special interest due its ferroelectric property

  5. Print Best jahib trükiteenuste turul liidrirolli / Toivo Tänavsuu

    Index Scriptorium Estoniae

    Tänavsuu, Toivo

    2004-01-01

    Konkursil Ettevõtluse auhind 2004 piirkonna edendaja nominentide hulka kuuluv Print Best on tõusnud viimase aastaga mahtudelt viie suurema poogentrükikoja hulka Eestis. Firma prioriteediks on Venemaa, mõeldud on müügiüksuse loomisele Moskvas. Lisa: Print Best Trükikoda

  6. Hans Georg Trüper (1936–2016 and His Contributions to Halophile Research

    Directory of Open Access Journals (Sweden)

    Aharon Oren

    2016-05-01

    Full Text Available Prof. Hans Georg Trüper, one of the most important scientists in the field of halophile research, passed away on 9 March 2016 at the age of 79. I here present a brief obituary with special emphasis on Prof. Trüper’s contributions to our understanding of the halophilic prokaryotes and their adaptations to life in hypersaline environments. He has pioneered the study of the halophilic anoxygenic phototrophic sulfur bacteria of the Ectothiorhodospira—Halorhodospira group. Some of the species he and his group isolated from hypersaline and haloalkaline environments have become model organisms for the study of the mechanisms of haloadaptation: the functions of three major organic compounds – glycine betaine, ectoine, and trehalose – known to serve as “compatible solutes” in halophilic members of the Bacteria domain, were discovered during studies of these anoxygenic phototrophs. Prof. Trüper’s studies of hypersaline alkaline environments in Egypt also led to the isolation of the first known extremely halophilic archaeon (Natronomonas pharaonis. The guest editors dedicate this special volume of Life to the memory of Prof. Hans Georg Trüper.

  7. Nicotine permeability across the buccal TR146 cell culture model and porcine buccal mucosa in vitro

    DEFF Research Database (Denmark)

    Nielsen, Hanne Mørck; Rassing, Margrethe Rømer

    2002-01-01

    The present study was conducted to investigate and compare the effect of pH and drug concentration on nicotine permeability across the TR146 cell culture model and porcine buccal mucosa in vitro. As a further characterization of the TR146 cell culture model, it was explored whether the results were...... comparable for bi-directional and uni-directional transport in the presence of a transmembrane pH gradient. Nicotine concentrations between 10(-5) and 10(-2) M were applied to the apical side of the TR146 cell culture model or the mucosal side of porcine buccal mucosa. Buffers with pH values of 5.5, 7...... concentrations of nicotine, the P(app) values decreased, which can partly be explained by an effect on the paracellular pathway. Similar results were also obtained when using the models for bi-directional as well as for uni-directional studies. The TR146 cell culture model may be used as model for buccal...

  8. 4R 31TR4SIE TY[)E~S [)IE EOEREOORLOG

    African Journals Online (AJOL)

    4R 31TR4SIE TY[)E~S [)IE. EOEREOORLOG. 4~GL( •. DIE 1899-KONVENSIE. VAN DEN HAAG. Die idee van 'n internasionale vredesbyeen- koms het in 1898 vanaf Russiese kant gekom. Op 24 Augustus 1898 het die Russiese mi- nister van Buitelandse Sake in die naam van tsaar Nicholas II 'n brief aan aile diplomatieke.

  9. Assessment of lnternational Space Station (ISS) Lithium-ion Battery Thermal Runaway (TR)

    Science.gov (United States)

    Graika, Jason

    2017-01-01

    This task was developed in the wake of the Boeing 787 Dreamliner lithium-ion battery TR incidents of January 2013 and January 2014. The Electrical Power Technical Discipline Team supported the Dreamliner investigations and has followed up by applying lessons learned to conduct an introspective evaluation of NASA's risk of similar incidents in its own lithium-ion battery deployments. This activity has demonstrated that historically NASA, like Boeing and others in the aerospace industry, has emphasized the prevention of TR in a single cell within the battery (e.g., cell screening) but has not considered TR severity-reducing measures in the event of a single-cell TR event. center dotIn the recent update of the battery safety standard (JSC 20793) to address this paradigm shift, the NASA community included requirements for assessing TR severity and identifying simple, low-cost severity reduction measures. This task will serve as a pathfinder for meeting those requirements and will specifically look at a number of different lithium-ion batteries currently in the design pipeline within the ISS Program batteries that, should they fail in a Dreamliner-like incident, could result in catastrophic consequences. This test is an abuse test to understand the heat transfer properties of the cell and ORU in thermal runaway, with radiant barriers in place in a flight like test in on orbit conditions. This includes studying the heat flow and distribution in the ORU. This data will be used to validate the thermal runaway analysis. This test does not cover the ambient pressure case. center dotThere is no pass/ fail criteria for this test.

  10. The Traffic Adaptive Data Dissemination (TrAD) Protocol for both Urban and Highway Scenarios.

    Science.gov (United States)

    Tian, Bin; Hou, Kun Mean; Zhou, Haiying

    2016-06-21

    The worldwide economic cost of road crashes and injuries is estimated to be US$518 billion per year and the annual congestion cost in France is estimated to be €5.9 billion. Vehicular Ad hoc Networks (VANETs) are one solution to improve transport features such as traffic safety, traffic jam and infotainment on wheels, where a great number of event-driven messages need to be disseminated in a timely way in a region of interest. In comparison with traditional wireless networks, VANETs have to consider the highly dynamic network topology and lossy links due to node mobility. Inter-Vehicle Communication (IVC) protocols are the keystone of VANETs. According to our survey, most of the proposed IVC protocols focus on either highway or urban scenarios, but not on both. Furthermore, too few protocols, considering both scenarios, can achieve high performance. In this paper, an infrastructure-less Traffic Adaptive data Dissemination (TrAD) protocol which takes into account road traffic and network traffic status for both highway and urban scenarios will be presented. TrAD has double broadcast suppression techniques and is designed to adapt efficiently to the irregular road topology. The performance of the TrAD protocol was evaluated quantitatively by means of realistic simulations taking into account different real road maps, traffic routes and vehicular densities. The obtained simulation results show that TrAD is more efficient in terms of packet delivery ratio, number of transmissions and delay in comparison with the performance of three well-known reference protocols. Moreover, TrAD can also tolerate a reasonable degree of GPS drift and still achieve efficient data dissemination.

  11. The Traffic Adaptive Data Dissemination (TrAD Protocol for both Urban and Highway Scenarios

    Directory of Open Access Journals (Sweden)

    Bin Tian

    2016-06-01

    Full Text Available The worldwide economic cost of road crashes and injuries is estimated to be US$518 billion per year and the annual congestion cost in France is estimated to be €5.9 billion. Vehicular Ad hoc Networks (VANETs are one solution to improve transport features such as traffic safety, traffic jam and infotainment on wheels, where a great number of event-driven messages need to be disseminated in a timely way in a region of interest. In comparison with traditional wireless networks, VANETs have to consider the highly dynamic network topology and lossy links due to node mobility. Inter-Vehicle Communication (IVC protocols are the keystone of VANETs. According to our survey, most of the proposed IVC protocols focus on either highway or urban scenarios, but not on both. Furthermore, too few protocols, considering both scenarios, can achieve high performance. In this paper, an infrastructure-less Traffic Adaptive data Dissemination (TrAD protocol which takes into account road traffic and network traffic status for both highway and urban scenarios will be presented. TrAD has double broadcast suppression techniques and is designed to adapt efficiently to the irregular road topology. The performance of the TrAD protocol was evaluated quantitatively by means of realistic simulations taking into account different real road maps, traffic routes and vehicular densities. The obtained simulation results show that TrAD is more efficient in terms of packet delivery ratio, number of transmissions and delay in comparison with the performance of three well-known reference protocols. Moreover, TrAD can also tolerate a reasonable degree of GPS drift and still achieve efficient data dissemination.

  12. Trânsito de suídeos em Minas Gerais, Brasil

    Directory of Open Access Journals (Sweden)

    C.S.F. Oliveira

    2013-10-01

    Full Text Available Minas Gerais ocupa a quarta posição entre os estados brasileiros com maior produção de suídeos. A suinocultura envolve intenso trânsito de animal e, consequentemente, forma complexas redes de fluxo. Com a movimentação, esses animais podem carrear agentes patogênicos que podem ser disseminados por meio dessa rede de contatos. Diante disso, este estudo tem como objetivo descrever e analisar o trânsito de suídeos em Minas Gerais para compreender os caminhos mais prováveis para a disseminação de possíveis surtos. Os dados foram fornecidos pelo Instituto Mineiro de Agropecuária, originados das 56.823 Guias de Trânsito Animal emitidas no ano de 2009. A movimentação dos 5.354.735 suídeos foi analisada segundo a sua finalidade. O trânsito mais intenso ocorreu com a finalidade de abate (79,95%, seguida pelas finalidades de engorda (10,64% e de reprodução (9,38%. A movimentação de animais para exposições e leilões representou apenas 0.03% dos transportes realizados. O trânsito em Minas Gerais é heterogêneo e concentra-se, principalmente, nas regiões do Triângulo Mineiro, Alto Paranaíba e Zona da Mata. As características do fluxo de animais tornam a utilização da estratégia das redes ideal para a elaboração das medidas de vigilância e controle das doenças dos suídeos em Minas Gerais.

  13. Magnetoelectric properties of nickel nanowires-P(VDF–TrFE) composites

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Thanh Hoai Lucie [Physique des Polymères, CIRIMAT – Institut Carnot, Université Paul Sabatier, 118 Route de Narbonne, 31062 Toulouse Cedex 9 (France); Laffont, Lydia [MEMO, CIRIMAT/Institut Carnot, ENSIACET, 4 Allée Emile Monso, BP 44362, 31030 Toulouse Cedex 4 (France); Capsal, Jean-Fabien; Cottinet, Pierre-Jean [LGEF-INSA Lyon, 8 Rue de la Physique, 69621 Villeurbanne Cedex (France); Lonjon, Antoine [Physique des Polymères, CIRIMAT – Institut Carnot, Université Paul Sabatier, 118 Route de Narbonne, 31062 Toulouse Cedex 9 (France); Dantras, Eric, E-mail: eric.dantras@univ-tlse3.fr [Physique des Polymères, CIRIMAT – Institut Carnot, Université Paul Sabatier, 118 Route de Narbonne, 31062 Toulouse Cedex 9 (France); Lacabanne, Colette [Physique des Polymères, CIRIMAT – Institut Carnot, Université Paul Sabatier, 118 Route de Narbonne, 31062 Toulouse Cedex 9 (France)

    2015-03-01

    Multiferroic composites with very high magnetoelectric coupling composites have been elaborated by incorporating high aspect ratio magnetic nickel particles in a ferroelectric matrix P(VDF–TrFE). Nickel nanowires (NWs) were elaborated by the electrodeposition method which allows obtaining a constant aspect ratio of 250. SEM-FEG images showed a Ni NWs homogeneous dispersion in acetone or in the P(VDF–TrFE). HR-TEM images and electronic diffraction studies revealed that the Ni NWs are monocrystalline, thanks to the electrodeposition method. Magnetic measurements showed a strong anisotropy of the magnetic particles, the coercivity is higher in the parallel direction (160 Oe). This anisotropy decreased for the composites due to the diminution of the Ni NWs interactions. The piezoelectric coefficient obtained after the composite polarization was significant (7 pC N{sup −1}) under a polarization field of 60 kV mm{sup −1}. The magnetoelectric coefficient reached the value of 237 V/(m Oe) at 4 kHz. According to the previous studies, this value is the highest one found for multiferroic polymer matrix composites. - Highlights: • A magnetic anisotropy of the ferromagnetic Ni nanowires was observed. • The P(VDF–TrFE) glass transition has an influence on the NWs Ni/P(VDF–TrFE) 0.3% vol composite magnetic properties. • The NWs Ni/P(VDF–TrFE) composite was polarized to obtain a significant piezoelectric coefficient of 7 pC N{sup −1}. • The magnetoelectric coefficient reached the high value of 237 V/(m Oe)

  14. Skador, skadeprevention och psykosociala faktorers betydelse för träning inom truppgymnastik : En intervjustudie med tränare för barn 8-12 år

    OpenAIRE

    Kammerfors, Emilia; Emilsson, Malin

    2017-01-01

    Syfte: Syftet med denna studie är att undersöka vad tränare inom truppgymnastik för barn mellan 8-12 år har för erfarenheter av skador och skadeförebyggande träning och hur man på bästa sätt främjar en stimulerande och motiverande träningsmiljö. Design och metod: Deskriptiv och explorativ kvalitativ design. Semistrukturerade intervjuer av fem tränare inom truppgymnastik för barn i åldern 8-12 år. Data bearbetades med kvalitativ innehållsanalys enligt Graneheim och Lundman. Resultat: Tränarna ...

  15. A inclusão de surdos no trânsito

    Directory of Open Access Journals (Sweden)

    Vânia Mendes de Souza

    Full Text Available RESUMO: Objetivo: investigar como se dá o processo de inclusão de surdos no cenário do trânsito. Métodos: participaram do estudo 20 sujeitos, divididos em três grupos: G1, composto por 10 surdos; G2 composto por cinco profissionais de uma instituição de referência em assistência a sujeitos com necessidades educacionais específicas e G3 composto por cinco profissionais de um Departamento Estadual de Trânsito. Foram aplicadas entrevistas gravadas em áudio e vídeo, cujas respostas foram analisadas por meio do software Qualiquantisoft e aquelas com sentido semelhante foram reunidas para a construção de discursos do sujeito coletivo, tendo como base o método proposto por Lefèvre e Lefèvre. Resultados: os discursos do sujeito coletivo apontam para dificuldades na acessibilidade de surdos no trânsito e no processo de obtenção e renovação da carteira nacional de habilitação. De uma forma geral, todos os grupos apontaram sugestões como: a necessidade de intérprete para mediar o processo, a capacitação de profissionais para atenderem surdos e a realização da prova teórica em Libras, utilizando recursos de vídeo. Conclusão: embora haja avanços, há inúmeras falhas no que se trata da acessibilidade de pessoas surdas tanto no processo de obtenção/renovação da carteira nacional de habilitação quanto no trânsito. Portanto, é urgente que seja discutida a realidade enfrentada por essa população, visando soluções que possam garantir aos surdos não apenas o acesso ao trânsito, mas também a construção e adequada execução de políticas públicas que venham a lhes fornecer acessibilidade e segurança.

  16. Transport and Fatigue Properties of Ferroelectric Polymer P(VDF-TrFE) For Nonvolatile Memory Applications

    KAUST Repository

    Hanna, Amir

    2012-06-01

    Organic ferroelectrics polymers have recently received much interest for use in nonvolatile memory devices. The ferroelectric copolymer poly(vinylidene fluoride- trifluoroethylene) , P(VDF-TrFE), is a promising candidate due to its relatively high remnant polarization, low coercive field, fast switching times, easy processability, and low Curie transition. However, no detailed study of charge injection and current transport properties in P(VDF-TrFE) have been reported in the literature yet. Charge injection and transport are believed to affect various properties of ferroelectric films such as remnant polarization values and polarization fatigue behavior.. Thus, this thesis aims to study charge injection in P(VDF-TrFE) and its transport properties as a function of electrode material. Injection was studied for Al, Ag, Au and Pt electrodes. Higher work function metals such as Pt have shown less leakage current compared to lower work function metals such as Al for more than an order of magnitude. That implied n-type conduction behavior for P(VDF-TrFE), as well as electrons being the dominant injected carrier type. Charge transport was also studied as a function of temperature, and two major transport regimes were identified: 1) Thermionic emission over a Schottky barrier for low fields (E < 25 MV/m). 2) Space-Charge-Limited regime at higher fields (25 < E <120 MV/m). We have also studied the optical imprint phenomenon, the polarization fatigue resulting from a combination of broad band optical illumination and DC bias near the switching field. A setup was designed for the experiment, and validated by reproducing the reported effect in polycrystalline Pb(Zr,Ti)O3 , PZT, film. On the other hand, P(VDF-TrFE) film showed no polarization fatigue as a result of optical imprint test, which could be attributed to the large band gap of the material, and the low intensity of the UV portion of the arc lamp white light used for the experiment. Results suggest using high work

  17. Autism Spectrum Disorders According to "DSM-IV-TR" and Comparison with "DSM-5" Draft Criteria: An Epidemiological Study

    Science.gov (United States)

    Mattila, Marja-Leena; Kielinen, Marko; Linna, Sirkka-Liisa; Jussila, Katja; Ebeling, Hanna; Bloigu, Risto; Joseph, Robert M.; Moilanen, Irma

    2011-01-01

    Objective: The latest definitions of autism spectrum disorders (ASDs) were specified in "DSM-IV-TR" in 2000. "DSM-5" criteria are planned for 2013. Here, we estimated the prevalence of ASDs and autism according to "DSM-IV-TR," clarified confusion concerning diagnostic criteria, and evaluated "DSM-5" draft…

  18. Tidlig struktureret mobilisering og træning af kritisk syge patienter på et dansk intensivafsnit

    DEFF Research Database (Denmark)

    Astrup Sørensen, Katrine; Hvid, Sidsel; Rolving, Nanna

    2015-01-01

    derimod anvendelig i forhold til at tilpasse niveauet for mobilisering og træning. Relevans for klinisk praksis: Tidlig mobilisering og træning er mulig at indføre med en simpel algoritme, dog med hensyntagen til individuelle screeningskriterier fra sted til sted, da disse åbenbart ikke er nemme...

  19. Factores tróficos en neuronas dopaminérgicas mesencefálicas

    Directory of Open Access Journals (Sweden)

    G. Pinzón

    1994-12-01

    Full Text Available Desde su descubrimiento, se ha postulado, y en algunos casos comprobado, que los factores tróficos juegan un papel importante en el desarrollo, mantenimiento y regeneración del sistema nervioso. El conocimiento y la manipulación de estas sustancias ha servido para: a formular nuevas teorías acerca de la etiología de varios desórdenes neurodebeneraivos y b desarrollar nuevas altemativas terapéuticas para estas entidades. En la presente revisión, resumimos los principales efectos de diferentes factores tróficos sobre las neuronas dopaminérgicas de la substantia nigra en desarrollo, cuya degeneración en el adulto ocasiona la mayoría de los síntomas observados en la enfermedad de Parkinson.

  20. Thermally rearranged (TR) polymer membranes with nanoengineered cavities tuned for CO2 separation

    Science.gov (United States)

    Kim, Seungju; Lee, Young Moo

    2012-07-01

    Membrane gas separation technology has been rapidly growing for industrial applications such as air separation, carbon dioxide (CO2) separation from natural gas production, hydrogen separation, etc. Needs for CO2 separation are increasing as carbon capture technology has been recognized as an essential part when combating the global warming issue. Membrane gas separation technology deals with mass transport phenomena through the membrane engineered on a sub-nanoscale controlling transport properties of small gas molecules such as CO2, N2, O2, H2, etc. In this review, we will report on the recent developments in capture technologies utilizing various membranes including nano-engineered thermally rearranged (TR) polymers. TR polymer membranes show high gas permeability as well as good separation properties, especially in CO2 separation processes such as from post-combustion flue gas and natural gas sweetening.

  1. Porto de Trás: etnicidade, turismo e patrimonialização

    Directory of Open Access Journals (Sweden)

    Patrícia de Araújo Brandão Couto

    2011-05-01

    Full Text Available The article describes the process by which cultural heritage of Porto de Trás, a neigborhood in Itacaré on the southern coast of Bahia, Brazil, has gained recognition. Porto de Trás is an ethnic community of African Brazilians with a tradition of artisanal fishing. Historically, its residents, organized in family groupings, have been segregated for their race and socioeconomic status.Even with the arrival of the tourist industry in the 1990s and concomitant urban developments, it maintained its traditional cultural practices, gaining recognition as an enclave of “authenticity” referred to local culture. Interactions between the different spheres of heritage operating in this space are discussed especially the construction of ethnicity by local residents.

  2. AN EFFICIENT DATA MINING METHOD TO FIND FREQUENT ITEM SETS IN LARGE DATABASE USING TR- FCTM

    Directory of Open Access Journals (Sweden)

    Saravanan Suba

    2016-01-01

    Full Text Available Mining association rules in large database is one of most popular data mining techniques for business decision makers. Discovering frequent item set is the core process in association rule mining. Numerous algorithms are available in the literature to find frequent patterns. Apriori and FP-tree are the most common methods for finding frequent items. Apriori finds significant frequent items using candidate generation with more number of data base scans. FP-tree uses two database scans to find significant frequent items without using candidate generation. This proposed TR-FCTM (Transaction Reduction- Frequency Count Table Method discovers significant frequent items by generating full candidates once to form frequency count table with one database scan. Experimental results of TR-FCTM shows that this algorithm outperforms than Apriori and FP-tree.

  3. Nätverksövervakning av trådlösa accesspunkter

    OpenAIRE

    Heino, Felix

    2016-01-01

    Syftet med examensarbetet är att analysera, implementera och utvärdera metoder för nätverksövervakning av trådlös kommunikationsutrustning i företaget Fibras nätverk. I dag sköts driften av cirka 2300 accesspunkter i Västerås stads trådlösa nätverk av Fibra. I nätverket ingår ett antal Wireless LAN Controller (WLC), vars uppgift är att hantera och konfigurera alla accesspunkter. Varje WLC kan hantera upp till 400 accesspunkter och sköter exempelvis autentiseringen av användarna. Dessutom finn...

  4. The SWISS-PROT protein sequence data bank and its supplement TrEMBL in 1998.

    Science.gov (United States)

    Bairoch, A; Apweiler, R

    1998-01-01

    SWISS-PROT (http://www.expasy.ch/) is a curated protein sequence database which strives to provide a high level of annotations (such as the description of the function of a protein, its domains structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases. Recent developments of the database include: an increase in the number and scope of model organisms; cross-references to two additional databases; a variety of new documentation files and improvements to TrEMBL, a computer annotated supplement to SWISS-PROT. TrEMBL consists of entries in SWISS-PROT-like format derived from the translation of all coding sequences (CDS) in the EMBL nucleotide sequence database, except the CDS already included in SWISS-PROT. PMID:9399796

  5. High-quality protein knowledge resource: SWISS-PROT and TrEMBL.

    Science.gov (United States)

    O'Donovan, Claire; Martin, Maria Jesus; Gattiker, Alexandre; Gasteiger, Elisabeth; Bairoch, Amos; Apweiler, Rolf

    2002-09-01

    SWISS-PROT is a curated protein sequence database which strives to provide a high level of annotation (such as the description of the function of a protein, its domain structure, post-translational modifications, variants, etc.), a minimal level of redundancy and a high level of integration with other databases. Together with its automatically annotated supplement TrEMBL, it provides a comprehensive and high-quality view of the current state of knowledge about proteins. Ongoing developments include the further improvement of functional and automatic annotation in the databases including evidence attribution with particular emphasis on the human, archaeal and bacterial proteomes and the provision of additional resources such as the International Protein Index (IPI) and XML format of SWISS-PROT and TrEMBL to the user community.

  6. The SWISS-PROT protein sequence data bank and its supplement TrEMBL in 1999.

    Science.gov (United States)

    Bairoch, A; Apweiler, R

    1999-01-01

    SWISS-PROT is a curated protein sequence database which strives to provide a high level of annotation (such as the description of the function of a protein, its domain structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases. Recent developments of the database include: cross-references to additional databases; a variety of new documentation files and improvements to TrEMBL, a computer annotated supplement to SWISS-PROT. TrEMBL consists of entries in SWISS-PROT-like format derived from the translation of all coding sequences (CDS) in the EMBL nucleotide sequence database, except the CDS already included in SWISS-PROT. The URLs for SWISS-PROT on the WWW are: http://www.expasy.ch/sprot and http://www. ebi.ac.uk/sprot

  7. Síndrome de Isaacs: relato de três casos

    Directory of Open Access Journals (Sweden)

    SCOLA ROSANA HERMÍNIA

    1999-01-01

    Full Text Available Relatamos três casos de síndrome de Isaacs, que apresentavam mioquímia clínica, cãibras, dificuldades para o relaxamento muscular, hipertrofia muscular e aumento da sudorese. A eletromiografia de agulha mostrou atividade muscular contínua involuntária, caracterizada como descargas mioquímicas. Os estudos da condução nervosa foram normais. Biópsia de músculo, realizado nos três casos, mostrou atrofia de fibras do tipo 2. Dois casos apresentaram melhora clínica com a utilização de carbamazepina e um com prednisona.

  8. P(VDF-TrFE Film on PDMS Substrate for Energy Harvesting Applications

    Directory of Open Access Journals (Sweden)

    Soaram Kim

    2018-01-01

    Full Text Available We have developed and demonstrated a highly flexible P(VDF-TrFE film-based energy harvesting device on a PDMS substrate, avoiding any complex composites and patterned structures. The structural and electrical properties of the P(VDF-TrFE film was investigated using multiple characterization techniques and an optimized film of 7 µm thickness was used for the energy harvesting application. The device, with Ti/Ni metal contacts, was driven by a shaker providing an acceleration of 1.75 g, and frequencies varying from 5 to 30 Hz. The energy harvesting performance of the final fabricated device was tested using the shaker, and resulted in a maximum output capacitor voltage of 4.4 V, which successfully powered a set of 27 LEDs after several minutes of charging.

  9. A case of pancreatic cancer with the sign of Leser-Trélat.

    Science.gov (United States)

    Hirano, T; Yoshioka, H; Manabe, T

    1993-07-01

    A case of 79-year-old man with pancreatic cancer associated with the sign of Leser-Trélat was presented. Abdominal CT scanning was performed and a pancreatic tail tumor involving the spleen and the greater omentum as well as ascitic retention were detected. Ba-enema study showed the stenosis of the sigmoid colon, suggesting the peritoneal disseminations. Absolute non-curative operation of side-to-side transverso-sigmoidostomy was performed for colonic stenosis, and biopsy of the disseminated omental tumor was performed, which was histologically diagnosed as well differentiated papillary adenocarcinoma compatible with pancreatic cancer. The postoperative course was uneventful and at present the patient was followed at outpatient clinic. To our knowledge, this case is the first report with pancreatic cancer associated with the sign of Leser-Trélat in Japan.

  10. Esforço para compreensão do sentido do trágico

    Directory of Open Access Journals (Sweden)

    Júlio César Mioto

    2010-05-01

    Full Text Available Em prisma (representativo de um esforço inicial, tenta-se apreender algo do sentido do trágico clássico. Está a se resolver num próximo encadeamento o que se pode retirar de uma reflexão inicial como esta: o trágico, o mítico, o psicológico e o filológico, são todos tópicos que são humildemente tematizados neste texto; ora na dimensão de um Para-si que às vezes faz a sua vantagem.

  11. El tránsito vehículo-peatonal desde un punto de vista psicocultural

    Directory of Open Access Journals (Sweden)

    Gilbert Ulloa Brenes

    2011-12-01

    Full Text Available El objetivo de este artículo es proponer una serie de insumos epistemológicos y teóricos, como aproximación psicocultural, desde la cual se entienda el tránsito de vehículos y peatones en calidad de campo cultural propio de la sociedad moderna industrializada. Dicha propuesta sintetiza parte de los resultados de una investigación básica previa. La idea central de este trabajo supone que, en el tránsito vehículo-peatonal, se expresan aspectos como el ideal del maquinismo, algunos elementos de la ideología capitalista y una forma particular de constitución de los sujetos que participan en él. La construcción teórica se basa en las tesis de Max Horkheimer sobre las determinaciones sociales en procesos como la percepción y la formación de conceptos, las formulaciones de Pierre Bourdieu respecto a la constitución de los campos sociales y la perspectiva de Jacques Lacan en torno a lo simbólico y la identificación. A partir de esta propuesta, se concluye que una perspectiva psicocultural del tránsito de vehículos y peatones se basaría en la indagación sobre la racionalidad y la ideología imperante en los fenómenos asociados al tránsito vehículo peatonal, en la consideración de la estructura particular de este campo y en la forma como lo simbólico ubica a los sujetos participantes en él.

  12. ¿Puede la música expresar lo trágico?

    Directory of Open Access Journals (Sweden)

    Enrico Fubini

    2013-12-01

    Full Text Available [ES] Este trabajo parte de la pregunta sobre si el arte musical es capaz de expresar realmente el sentimiento trágico, e intenta clarificar la relación que existe (si existe entre el concepto de lo trágico y el lenguaje de la música. En concreto, se trata de reconstruir la historia de esta relación empezando por sus raíces, hundidas en la tragedia griega, para llegar a sus más cercanas expresiones en el siglo XX. Se pone el acento en el valor trágico del propio contenido musical, destacando con atención, en el caso del melodrama, la relación que surge entre una emoción expresada en palabras y aquella que nace de la música misma, así como la contradicción aparente entre la belleza de la armonía de la música polifónica con el sentimiento de lo verdaderamente trágico. ; [EN] This writing raises the question if the musical art is able to really express the feeling of the tragic, and tries to clarify the relation that exist (if it exists between the concept of the tragic and the language of music. In particular, it aims to reconstruct the history of this relation beginning by its roots, sunk in Greek tragedy, to arrive at its nearer expressions in the XX century. The accent is on the tragic value of the musical content itself, emphasizing in particular, in the case of the melodrama, the relation that arise between an emotion expressed in words and that that is born of music itself, as well as the apparent contradiction between the beauty of the harmony of polyphonic music and the feeling of the truly tragic.

  13. La socialisation sexospécifique des très jeunes adolescents à l ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Les adolescents de l'Afrique subsaharienne, en particulier ceux issus de zones urbaines à faible revenu, sont très vulnérables en ce qui concerne la santé sexuelle et reproductive. La plupart des interventions visant à améliorer la santé sexuelle et reproductive des adolescents sont axées sur les adolescents plus âgés et ...

  14. Sensitivity of diamond-capped impedance transducer to Tröger’s base derivatives

    Czech Academy of Sciences Publication Activity Database

    Stehlík, Štěpán; Ižák, Tibor; Kromka, Alexander; Dolenský, B.; Havlík, M.; Rezek, Bohuslav

    2012-01-01

    Roč. 4, č. 8 (2012), s. 3860-3865 ISSN 1944-8244 R&D Projects: GA ČR(CZ) GBP108/12/G108 Institutional research plan: CEZ:AV0Z10100521 Keywords : Tröger’s base derivative * nanocrystalline diamond * chemical sensor * impedance spectroscopy * surface conductivity Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 5.008, year: 2012

  15. Patterns of sitting and mortality in the Nord-Trøndelag health study (HUNT)

    OpenAIRE

    Grunseit, Anne C.; Chau, Josephine Y.; Rangul, Vegar; Holmen, Turid Lingaas; Bauman, Adrian

    2017-01-01

    Background Current evidence concerning sedentary behaviour and mortality risk has used single time point assessments of sitting. Little is known about how changes in sitting levels over time affect subsequent mortality risk. Aim To examine the associations between patterns of sitting time assessed at two time points 11 years apart and risk of all-cause and cardio-metabolic disease mortality. Methods Participants were 25,651 adults aged > =20 years old from the Nord-Trøndel...

  16. Discordance gradient-surface dans le rétrécissement mitral: le ...

    African Journals Online (AJOL)

    Il s'agit d'une étude transversale monocentrique incluant tous les patients admis au service de Cardiologie du CHU Ibn Rochd de Casablanca pour un RM serré ou très serré, sur une période d'une année (Janvier 2014 à Décembre 2014). Nous avons analysés séparément deux groupes de patients : ceux avec un gradient ...

  17. Chef, Opérations de trésorerie | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Préparer des analyses techniques des normes IFRS concernant les nouvelles normes ou celles qui connaissent des évolutions. Examiner et approuver les procédures financières après établissement et révision dans le domaine des opérations de trésorerie. Le chef est responsable des activités en cours en matière de ...

  18. Advanced Packaging Materials and Techniques for High Power TR Module: Standard Flight vs. Advanced Packaging

    Science.gov (United States)

    Hoffman, James Patrick; Del Castillo, Linda; Miller, Jennifer; Jenabi, Masud; Hunter, Donald; Birur, Gajanana

    2011-01-01

    The higher output power densities required of modern radar architectures, such as the proposed DESDynI [Deformation, Ecosystem Structure, and Dynamics of Ice] SAR [Synthetic Aperture Radar] Instrument (or DSI) require increasingly dense high power electronics. To enable these higher power densities, while maintaining or even improving hardware reliability, requires advances in integrating advanced thermal packaging technologies into radar transmit/receive (TR) modules. New materials and techniques have been studied and compared to standard technologies.

  19. Física Aplicada ao Trânsito: Uma revisão de Literatura

    Directory of Open Access Journals (Sweden)

    Patrick Alves Vizzotto

    2017-02-01

    Full Text Available Uma das formas de se abordar a Física na Educação Básica para que sua aprendizagem possa ganhar maior significado é abordando fenômenos que façam parte da vida dos estudantes, como por exemplo as situações aplicadas no trânsito. Este artigo apresenta resultados obtidos de uma pesquisa bibliométrica sobre a produção acadêmica nacional da temática Física aplicada ao trânsito. O objetivo foi realizar uma revisão de literatura e analisar o estado da arte da produção acadêmica citada a fim de observar de que forma a temática vem sendo trabalhada na pesquisa e no ensino. A busca recuperou 2491 documentos, porém apenas 20 foram aproveitados na temática de interesse. Entre as ideias em comum levantadas, encontramos a importância de abordar o tema trânsito durante todos os anos da educação básica; a relevância da contextualização no Ensino de Física; e a influência dos aspectos emocionais na aprendizagem. Constatamos que, apesar do grande potencial para o ensino de Física, pouco tem se desenvolvido em pesquisas sobre o tema. Isso pode explicar a dificuldade na compreensão e assimilação de conceitos físicos amplamente utilizados no cotidiano do trânsito.

  20. Investigation of unsteady flow development over a pitching airfoil by means of TR-PIV

    OpenAIRE

    Mulleners, Karen; Henning, Arne; Mai, Holger; Raffel, Markus; Costes, Michel; Le Pape, Arnaud

    2009-01-01

    The flow over an OA209 airfoil subjected to a sinusoidal pitching motion under dynamic stall conditions is investigated experimentally by means of time resolved particle image velocimetry (TR-PIV) and surface pressure measurements. Dynamic stall is distinguished by the formation and convection of large scale coherent structures and a delay in massive flow separation. A vortex detection scheme based on an identification function derived directly from the velocity fields is adopted to identify ...

  1. Trådbindere til forankring af skalmure og hule mure

    DEFF Research Database (Denmark)

    Høffding Knutsson, H.

    Anvisningen er et hjælpemiddel for projekterende, udførende og kontrollerende parter ved dimensionering, montering og vurdering af trådbindere. Den indeholder bæreevnediagrammer for de gængse størrelser bindere i tinbronze og rustfri stål, både bæreevnen af retlinede bindere, men også den...

  2. Detection of Planetary Emission from the Exoplanet TrES-2 Using Spitzer/IRAC

    Science.gov (United States)

    Donovan, Francis T.; Charbonneau, David; Harrington, Joseph; Madhusudhan, N.; Seager, Sara; Deming, Drake; Knutson, Heather A.

    2010-01-01

    We present here the results of our observations of TrES-2 using the Infrared Array Camera on Spitzer. We monitored this transiting system during two secondary eclipses, when the planetary emission is blocked by the star. The resulting decrease in flux is 0.127% +/- 0.021%, 0.230% +/- 0.024%, 0.199% +/- 0.054%, and 0.359% +/- 0.060% at 3.6 microns, 4.5 microns, 5.8 microns, and 8.0 microns, respectively. We show that three of these flux contrasts are well fit by a blackbody spectrum with T(sub eff) = 1500 K, as well as by a more detailed model spectrum of a planetary atmosphere. The observed planet-to-star flux ratios in all four lRAC channels can be explained by models with and without a thermal inversion in the atmosphere of TrES-2, although with different atmospheric chemistry. Based on the assumption of thermochemical equilibrium, the chemical composition of the inversion model seems more plausible, making it a more favorable scenario. TrES-2 also falls in the category of highly irradiated planets which have been theoretically predicted to exhibit thermal inversions. However, more observations at infrared and visible wavelengths would be needed to confirm a thermal inversion in this system. Furthermore, we find that the times of the secondary eclipses are consistent with previously published times of transit and the expectation from a circular orbit. This implies that TrES-2 most likely has a circular orbit, and thus does not obtain additional thermal energy from tidal dissipation of a non-zero orbital eccentricity, a proposed explanation for the large radius of this planet. Key words: eclipses - infrared: stars - planetary systems - stars: individual (OSC 03549-02811) - techniques: photometric

  3. VIDA-træningsprogram til ledelsesfacilitering af læreprocesser

    DEFF Research Database (Denmark)

    Ravn, Ib; Tange, Nina

    2013-01-01

    Som led i VIDA-projektet blev de ca. 80 deltagende ledere af daginstitutioner tilbudt træningsforløb i facilitering. Facilitering er en tilgang, der sætter ledere i stand til at guide og støtte medarbejderinddragelsen på en sådan måde, at alle føler sig hørt, og der bliver skabt resultater på...

  4. Nicotine permeability across the buccal TR146 cell culture model and porcine buccal mucosa in vitro

    DEFF Research Database (Denmark)

    Nielsen, Hanne Mørck; Rassing, Margrethe Rømer

    2002-01-01

    The present study was conducted to investigate and compare the effect of pH and drug concentration on nicotine permeability across the TR146 cell culture model and porcine buccal mucosa in vitro. As a further characterization of the TR146 cell culture model, it was explored whether the results were...... comparable for bi-directional and uni-directional transport in the presence of a transmembrane pH gradient. Nicotine concentrations between 10(-5) and 10(-2) M were applied to the apical side of the TR146 cell culture model or the mucosal side of porcine buccal mucosa. Buffers with pH values of 5.5, 7.......4 and 8.1 were used to obtain different fractions of non- and mono-ionized nicotine. The apparent permeability (P(app)) of nicotine across both models increased significantly with increasing pH, and the P(app) values obtained with the two models could be correlated in a linear manner. With increasing...

  5. Organisation and standardisation of information in SWISS-PROT and TrEMBL

    Directory of Open Access Journals (Sweden)

    Michele Magrane

    2006-01-01

    Full Text Available SWISS-PROT is a curated, non-redundant protein sequence database which provides a high level of annotation and is integrated with a large number of other biological databases. It is supplemented by TrEMBL, a computer-annotated database which contains translations of all coding sequences in the EMBL Nucleotide Sequence Database which are not yet in SWISS-PROT. Each fully curated SWISS-PROT entry contains as much up-to-date information as possible from a variety of sources and the high quality of the annotation in SWISS-PROT provides the basis for the procedure which is used to automatically annotate the TrEMBL database. The large amounts of different data types found in both databases are stored in a highly structured and uniform manner and this structured organisation means that SWISS-PROT and TrEMBL together provide a comprehensive resource with data that are readily accessible for users and easily retrievable by computer programs.

  6. Tempo e Trânsito na Experiência Subjetiva de Motoristas

    Directory of Open Access Journals (Sweden)

    Ana Inez Oka Elvas de Lima

    2015-03-01

    Full Text Available Esta pesquisa investiga como são percebidos e vivenciados o tempo e a pressa no trânsito por motoristas de Fortaleza, identificando e analisando seus estados subjetivos e comportamentos associados a essa experiência. Para a coleta de dados, organizaram-se quatro grupos focais, a partir dos quais emergiram diversos elementos relacionados ao tempo e à pressa e à incidência de comportamentos inadequados no trânsito, segundo o sexo e a idade dos participantes. Para analisar os dados obtidos nas discussões grupais utilizaram-se os critérios da Análise Clássica de Conteúdo. Os resultados levaram à conclusão de que a questão do tempo e da pressa constitui um potencial gerador de erros e violações na condução de veículos, pois exerce influência decisiva sobre os comportamentos dos motoristas e configura uma realidade importante para se compreender os fatores humanos envolvidos na dinâmica do trânsito e do ambiente urbano como um todo.

  7. Bezdarbs un trūcīgo statuss Latvijā

    OpenAIRE

    Koškarjova, Juliana

    2012-01-01

    Galvenā tirgus ekonomikas problēma ir bezdarbs, ar ko saskaras arī Latvijas iedzīvotāji. Bezdarbs izraisa ne tikai ekonomiskas problēmas, bet arī sociālās, tādas kā sociālā atstumtība, trūcīgo personu skaita pieaugumu.Minētā problēma traucē sabiedrībai attīstīties. Pētījuma mērķis ir izpētīt bezdarba problēmu un izanalizēt trūcīgo personu statusu Latvijā, un uz tā pamata izdarīt secinājumus un sniegt konkrētus priekšlikumus. Pētījuma pirmajā daļā tiek aplūkoti bezdarba un trūcīgo statu...

  8. Mortes no trânsito do Rio de Janeiro, Brasil

    Directory of Open Access Journals (Sweden)

    Klein Carlos Henrique

    1994-01-01

    Full Text Available A evolução urbana do município do Rio de Janeiro durante o século XX, especialmente a partir da sua segunda metade, é fortemente marcada por crescentes privilégios concedidos ao crescimento da utilização dos meios de transporte de massa e, principalmente, individuais, feitos por veículos a motor de explosão. Uma das conseqüências desta política é a ascenção da mortalidade por acidentes de trânsito, verificada durante a década de 80, entre homens e mulheres de todas as idades. Neste trabalho demonstra-se também que, em 1990, apenas cerca de 1/3 das vítimas fatais nos acidentes de trânsito estavam "embarcadas" nos veículos. Portanto, a maioria dos óbitos por este tipo de acidente, cerca de 2/3, ocorreu por atropelamentos. Isto indica a necessidade de o poder público reverter a prioridade na prevenção das mortes por acidentes de trânsito em favor de medidas eficazes que protejam os pedestres.

  9. Mortes no trânsito do Rio de Janeiro, Brasil

    Directory of Open Access Journals (Sweden)

    Carlos Henrique Klein

    Full Text Available A evolução urbana do município do Rio de Janeiro durante o século XX, especialmente a partir da sua segunda metade, é fortemente marcada por crescentes privilégios concedidos ao crescimento da utilização dos meios de transporte de massa e, principalmente, individuais, feitos por veículos a motor de explosão. Uma das conseqüências desta política é a ascenção da mortalidade por acidentes de trânsito, verificada durante a década de 80, entre homens e mulheres de todas as idades. Neste trabalho demonstra-se também que, em 1990, apenas cerca de 1/3 das vítimas fatais nos acidentes de trânsito estavam "embarcadas" nos veículos. Portanto, a maioria dos óbitos por este tipo de acidente, cerca de 2/3, ocorreu por atropelamentos. Isto indica a necessidade de o poder público reverter a prioridade na prevenção das mortes por acidentes de trânsito em favor de medidas eficazes que protejam os pedestres.

  10. Three component velocity extraction method using TR-PIV in a microtube

    Science.gov (United States)

    Erkan, Nejdet; Okamoto, Koji; Someya, Satoshi

    2007-11-01

    Measurement of three-component (3C) velocity field in the microfluidic devices with the conventional techniques and conventional micro-PIV (Particle Image Velocimetry) is still difficult due to the limited optical access to the microscale flow fields. Since Santiago et al (1998), micro-PIV flow velocity measurements have remained mainly limited to the 2C velocity vector field realizations. In this study, third component of the velocity i.e. out-of-plane velocity extraction from two-dimensional time resolved (TR) micro-PIV images is proposed. The method is based on PIV and performs cross-correlation (CC) peak height tracking inside the small ensembles of the TR-PIV flow images. This concept was verified basically by the simulation employing synthetic micro TR-PIV images. It was also demonstrated by an experiment erformed on a microscale fluid flow inside a 100μm diameter inclined micro tube. Despite the inevitable background noise which effects the measurement negatively, extracted steady-state depthwise velocity profile was in agreement with the analytical result.

  11. TR-PIV Performance Test for a Flow Field Measurement in a Single Rod Test Section

    Energy Technology Data Exchange (ETDEWEB)

    Park, Ju Yong; Shin, Chang Hwan; Lee, Chi Young; Oh, Dong Seok; In, Wang Kee [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2011-10-15

    For large enhancement of performance of Pressurized Water Reactor(PWR), dual-cooled fuel is being developed in Korea Atomic Energy Research Institute(KAERI). This nuclear fuel is a ring shape fuel which is different from conventional cylindrical nuclear fuel and cooling water flows both inner and outer channel. For this fuel, it widens the surface area. But it is bigger outer diameter of fuel rods. So, interval between fuel rods narrows. This because of outer channel flow is unstable. So, measurement of turbulence flow and perturbation that influence in heat transfer elevation is important.. To understand heat transfer characteristics by turbulence, measurement of flow perturbation element is necessary. To measure these turbulence characteristics, hot wire anemometer is widely used. However, it has many disadvantages such as low durability of prove, and big probe size. For these reasons, TR-PIV(Time-Resolved Particle Image Velocimetry) system is employed for better flow measurement in our research institute. TR-PIV system is consisted of laser system and high-speed camera that have high frequency. So, was judged that can measurement complicated turbulence flow and perturbation. In this paper, introduce TR-PIV system, and with results acquiring in single rod flow through this system, and wish to introduce about after this practical use plan

  12. TR-PIV Performance Test for a Flow Field Measurement in a Single Rod Test Section

    International Nuclear Information System (INIS)

    Park, Ju Yong; Shin, Chang Hwan; Lee, Chi Young; Oh, Dong Seok; In, Wang Kee

    2011-01-01

    For large enhancement of performance of Pressurized Water Reactor(PWR), dual-cooled fuel is being developed in Korea Atomic Energy Research Institute(KAERI). This nuclear fuel is a ring shape fuel which is different from conventional cylindrical nuclear fuel and cooling water flows both inner and outer channel. For this fuel, it widens the surface area. But it is bigger outer diameter of fuel rods. So, interval between fuel rods narrows. This because of outer channel flow is unstable. So, measurement of turbulence flow and perturbation that influence in heat transfer elevation is important.. To understand heat transfer characteristics by turbulence, measurement of flow perturbation element is necessary. To measure these turbulence characteristics, hot wire anemometer is widely used. However, it has many disadvantages such as low durability of prove, and big probe size. For these reasons, TR-PIV(Time-Resolved Particle Image Velocimetry) system is employed for better flow measurement in our research institute. TR-PIV system is consisted of laser system and high-speed camera that have high frequency. So, was judged that can measurement complicated turbulence flow and perturbation. In this paper, introduce TR-PIV system, and with results acquiring in single rod flow through this system, and wish to introduce about after this practical use plan

  13. T1-weighted vs. short-TE-long-TR images. Usefulness for knee MR examinations of ligament and meniscal lesions

    Energy Technology Data Exchange (ETDEWEB)

    Endo, Hideho; Wada, Mitsuyoshi; Shiotani, Seiji [Tsukuba Medical Center Hospital, Ibaraki (Japan); Niitsu, Mamoru; Itai, Yuji

    2000-11-01

    The purpose of this study was to compare short-TE-long-TR images with T1-weighed images in knee MR examinations. Sagittal MR images of the knee were obtained in 31 patients with knee pain. T1-weighted images were obtained by the spin-echo technique (TR/TE =350/15), and short-TE-long-TR images by fast spin-echo (TR/TE =1300/15) with an echo-train length of 5. Contrast-to-noise-ratios (CNRs) of the anterior cruciate ligament and synovial space, meniscus and articular cartilage, and meniscal lesion and normal meniscus were compared between short-TE-long-TR images and T1-weighted images. On each of the three examinations, short-TE-long-TR images provided significantly higher CNRs than T1-weighted images. It was concluded that short-TE-long-TR images can be a useful alternative to T1-weighted images in evaluating the anterior cruciate ligament and meniscal lesions. (author)

  14. T1-weighted vs. short-TE-long-TR images. Usefulness for knee MR examinations of ligament and meniscal lesions

    International Nuclear Information System (INIS)

    Endo, Hideho; Wada, Mitsuyoshi; Shiotani, Seiji; Niitsu, Mamoru; Itai, Yuji

    2000-01-01

    The purpose of this study was to compare short-TE-long-TR images with T1-weighed images in knee MR examinations. Sagittal MR images of the knee were obtained in 31 patients with knee pain. T1-weighted images were obtained by the spin-echo technique (TR/TE =350/15), and short-TE-long-TR images by fast spin-echo (TR/TE =1300/15) with an echo-train length of 5. Contrast-to-noise-ratios (CNRs) of the anterior cruciate ligament and synovial space, meniscus and articular cartilage, and meniscal lesion and normal meniscus were compared between short-TE-long-TR images and T1-weighted images. On each of the three examinations, short-TE-long-TR images provided significantly higher CNRs than T1-weighted images. It was concluded that short-TE-long-TR images can be a useful alternative to T1-weighted images in evaluating the anterior cruciate ligament and meniscal lesions. (author)

  15. Involvement of TR3/Nur77 translocation to the endoplasmic reticulum in ER stress-induced apoptosis

    International Nuclear Information System (INIS)

    Liang Bin; Song Xuhong; Liu Gefei; Li Rui; Xie Jianping; Xiao Lifeng; Du Mudan; Zhang Qiaoxia; Xu Xiaoyuan; Gan Xueqiong; Huang Dongyang

    2007-01-01

    Nuclear orphan receptor TR3/Nur77/NGFI-B is a novel apoptotic effector protein that initiates apoptosis largely by translocating from the nucleus to the mitochondria, causing the release of cytochrome c. However, it is possible that TR3 translocates to other organelles. The present study was designed to determine the intracellular localization of TR3 following CD437-induced nucleocytoplasmic translocation and the mechanisms involved in TR3-induced apoptosis. In human neuroblastoma SK-N-SH cells and human esophageal squamous carcinoma EC109 and EC9706 cells, 5 μM CD437 induced translocation of TR3 to the endoplasmic reticulum (ER). This distribution was confirmed by immunofluorescence analysis, subcellular fractionation analysis and coimmunoprecipitation analysis. The translocated TR3 interacted with ER-targeting Bcl-2; initiated an early release of Ca 2+ from ER; resulted in ER stress and induced apoptosis through ER-specific caspase-4 activation, together with induction of mitochondrial stress and subsequent activation of caspase-9. Our results identified a novel distribution of TR3 in the ER and defined two parallel mitochondrial- and ER-based pathways that ultimately result in apoptotic cell death

  16. Um Modelo para Identificação de Tráfico de Animais Silvestres na Internet

    OpenAIRE

    Carrasco, Rafael da Silva

    2012-01-01

    O tráfico de animais silvestres figura entre as várias formas de crime praticadas na Internet. A dimensão do tráfico de animais silvestres demanda muito esforço por parte das autoridades especializadas em combatê-lo. Infelizmente, estes últimos dispõem de poucos recursos. Acredita-se que sistemas de monitoramento automático sejam capazes de oferecer um grande ganho em termos de produtividade no combate ao tráfico de animais silvestres. O monitoramento de tais atividades criminosas na Inter...

  17. Gümnaasiumi trükkal ja keskvõimu korralduste publitseerimine 17. sajandi lõpu Tallinnas / Kaarel Vanamölder

    Index Scriptorium Estoniae

    Vanamölder, Kaarel, 1981-

    2011-01-01

    Trükkal Christoph Brendekenist. Trükkali sissetulekutest ja töö est küsitavast tasust. Plakatite tiraažist. Kindralkuberneri kantselei publitseerimisrutiinist ning korralduste edastamise kiirusest

  18. Single-Chip T/R Module for 1.2 GHz

    Science.gov (United States)

    Moussessian, Alina; Mojarradi, Mohammad; Johnson, Travis; Davis, John; Grigorian, Edwin; Hoffman, James; Caro, Edward; Kuhn, William

    2006-01-01

    A single-chip CMOS-based (complementary-metal-oxide-semiconductorbased) transmit/receive (T/R) module is being developed for L-band radar systems. Previous T/R module implementations required multiple chips employing different technologies (GaAs, Si, and others) combined with off-chip transmission lines and discrete components including circulators. The new design eliminates the bulky circulator, significantly reducing the size and mass of the T/R module. Compared to multi-chip designs, the single-chip CMOS can be implemented with lower cost. These innovations enable cost-effective realization of advanced phased array and synthetic aperture radar systems that require integration of thousands of T/R modules. The circulator is a ferromagnetic device that directs the flow of the RF (radio frequency) power during transmission and reception. During transmission, the circulator delivers the transmitted power from the amplifier to the antenna, while preventing it from damaging the sensitive receiver circuitry. During reception, the circulator directs the energy from the antenna to the low-noise amplifier (LNA) while isolating the output of the power amplifier (PA). In principle, a circulator could be replaced by series transistors acting as electronic switches. However, in practice, the integration of conventional series transistors into a T/R chip introduces significant losses and noise. The prototype single-chip T/R module contains integrated transistor switches, but not connected in series; instead, they are connected in a shunt configuration with resonant circuits (see figure). The shunt/resonant circuit topology not only reduces the losses associated with conventional semiconductor switches but also provides beneficial transformation of impedances for the PA and the LNA. It provides full singlepole/ double-throw switching for the antenna, isolating the LNA from the transmitted signal and isolating the PA from the received signal. During reception, the voltage on

  19. Electrochemical performance in the hydrogen evolution reaction of Ni-TR (TR= La, Ce) materials synthesized using the solid state reaction method; Desempeno electroquimico en la reaccion de evolucion de hidrogeno de materiales de electrodo Ni-TR (TR = La, Ce) sintetizados por el metodo de reaccion de estado solido

    Energy Technology Data Exchange (ETDEWEB)

    Torres-Huerta, A. M.; Dominguez-Crespo, M. A.; Ramirez-Meneses, E.; Yanez-Zamora, C. [CICATA, IPN, Altamira, Tamaulipas (Mexico); Avila-Garcia, I. [IPN, ESIQIE, UPALM, Mexico, D.F. (Mexico)]. E-mail: mdominguezc@ipn.mx; adcrespo2000@yahoo.com.mx

    2009-09-15

    At the industrial level, the use of fuel cell technology is still limited because of the high costs of its parts and costs related to its operations. Although the electrode material with greater electroactivity is Pt, because of its high cost, alternative electrocatalysts have been sought that balance cost and activity. One of the materials that have been most widely used is nickel, along with some of its alloys. This material has shown good performance using low overpotentials in traditional reactions such as hydrogen (HER) and oxygen (OER) evolution, as well as high resistance to corrosion and low costs. In particular, binary and ternary alloys have shown significant increases in HER activity when compared to materials in the pure or massive state. Therefore, in the search for new alternatives with acceptable efficiency and low-cost, this work obtained Ni-TR (TR = La, Ce) using solid-state reaction with metallic acetylacetonates and metallic powder. These materials were synthesized for 3 h at different temperatures (795 or 920, 1000 and 1200 degrees Celsius) in order to evaluate the effect on the electrochemical performance of the electrocatalysts. The structural and morphological characterization of materials was performed with XRD and SEM techniques, respectively. In addition, the electrochemical performance of electrode materials was evaluated with HER using cyclic voltametry (CV) and potentiodynamic curves. The results obtained show that a combination of oxides was obtained (NiO, CeO{sub 2} and LaNiO{sub 3}) at low temperatures; nonetheless, as the synthesis temperatures increase, NiO-CeO{sub 2} and NiO-LaNiO{sub 3} alloys are formed, respectively. A clear dependence was also observed between electrocatalytic activity and the source for obtaining these materials(Ni-TR). [Spanish] A nivel industrial, el uso de la tecnologia de celdas de combustible esta todavia limitada debido sobre todo a los altos costos de las partes que la constituyen y los costos

  20. El espectro de KX TrA entre 1990 y 1996

    Science.gov (United States)

    Brandi, E.; García, L.; Ferrer, O.; Barbá, R.

    La estrella simbiótica KX TrA = He2-177 fue observada espectroscópicamente con el telescopio de 2.15 m del CASLEO entre los años 1990 y 1996, utilizándose resoluciones intermedia y alta. El rango espectral estudiado se extiende desde 4400 Åa 7200 Å. La historia fotométrica de KX TrA presenta explosiones del mismo tipo que las mostradas por la nova lenta RR Tel y su espectro de alta excitación, muy rico en líneas de emisión, es también similar al de RR Tel. Por lo tanto, es importante analizar la evolución espectral de KX TrA en el tiempo, prestando especial atención a los posibles cambios en los niveles de excitación. Las emisiones presentes corresponden a transiciones permitidas y prohibidas con un amplio rango de ionización, incluyéndose las anchas e intensas líneas originadas por scattering Raman de O VI en λλ 6825 y 7082 Å. En el período cubierto por nuestras observaciones se estudia la variación de la intensidad relativa de las emisiones, el comportamiento de las velocidades radiales y los cambios de perfiles de las líneas, especialmente en Hα y Hβ. El contínuo de la región roja observada indica un tipo espectral no más tardío que M3 para la componente gigante fría del sistema.

  1. A Spitzer five-band analysis of the Jupiter-sized planet TrES-1

    Energy Technology Data Exchange (ETDEWEB)

    Cubillos, Patricio; Harrington, Joseph; Foster, Andrew S. D.; Lust, Nate B.; Hardy, Ryan A.; Bowman, M. Oliver [Planetary Sciences Group, Department of Physics, University of Central Florida, Orlando, FL 32816-2385 (United States); Madhusudhan, Nikku, E-mail: pcubillos@fulbrightmail.org [Department of Physics and Department of Astronomy, Yale University, New Haven, CT 06511 (United States)

    2014-12-10

    With an equilibrium temperature of 1200 K, TrES-1 is one of the coolest hot Jupiters observed by Spitzer. It was also the first planet discovered by any transit survey and one of the first exoplanets from which thermal emission was directly observed. We analyzed all Spitzer eclipse and transit data for TrES-1 and obtained its eclipse depths and brightness temperatures in the 3.6 μm (0.083% ± 0.024%, 1270 ± 110 K), 4.5 μm (0.094% ± 0.024%, 1126 ± 90 K), 5.8 μm (0.162% ± 0.042%, 1205 ± 130 K), 8.0 μm (0.213% ± 0.042%, 1190 ± 130 K), and 16 μm (0.33% ± 0.12%, 1270 ± 310 K) bands. The eclipse depths can be explained, within 1σ errors, by a standard atmospheric model with solar abundance composition in chemical equilibrium, with or without a thermal inversion. The combined analysis of the transit, eclipse, and radial-velocity ephemerides gives an eccentricity of e=0.033{sub −0.031}{sup +0.015}, consistent with a circular orbit. Since TrES-1's eclipses have low signal-to-noise ratios, we implemented optimal photometry and differential-evolution Markov Chain Monte Carlo (MCMC) algorithms in our Photometry for Orbits, Eclipses, and Transits pipeline. Benefits include higher photometric precision and ∼10 times faster MCMC convergence, with better exploration of the phase space and no manual parameter tuning.

  2. Study on the curie transition of P(VDF-TrFE) copolymer

    Science.gov (United States)

    Eka Septiyani Arifin, Devi; Ruan, J. J.

    2018-01-01

    A systematic study was carried out to decipher the mechanism of Curie transition of piezoelectric crystals of poly(vinylidene fluoride trifluoroethylene) P(VDF-TrFE). The unique polarity of P(VDF-TrFE) crystalline phase below curie transition temperature is attributed to the lattice packing of all-trans molecular chains, which allocates all the substituted fluorine atoms on one side of molecular chains and hydrogen atoms on the other side. Therefore, a net dipole moment is created across the lateral packing of molecular chains. Nevertheless, due to the mutual repulsion among fluorene atoms, this all-trans conformation is not stable, and ready to change above Curie temperature, where thermal kinetic energy is sufficient to cause segmental rotation. As being illustrated by in-situ recorded X-ray diffraction and thermal analysis, the concerned curie transition is deciphered as a one-step process which is involved two process and this is different from conventional one-step solid-solid transitions. Accompanied with this one-step process during heating, the occurrence of lamellar bending is inferred for elucidating the decline of stacking regularity of crystalline lamellae, which reversibly recover during subsequent cooling. However, as the crystalline lamellae of P(VDF-TrFE) are confined in between the stacking of crystalline lamellae of PVDF, lamellar bending is restricted accordingly. As a result, a certain fraction of the piezoelectric crystalline lamellae was found to survive through the Curie transition. Thus, in addition to the suggestion of a one-step process as a new concept for understanding the Curie transition, the relationship between the lamellar stacking and transition of molecular packing is unveiled as well in this research.

  3. Involvement of p38-βTrCP-Tristetraprolin-TNFα axis in radiation pneumonitis.

    Science.gov (United States)

    Krishnamurthy, Pranathi Meda; Shukla, Shirish; Ray, Paramita; Mehra, Rohit; Nyati, Mukesh K; Lawrence, Theodore S; Ray, Dipankar

    2017-07-18

    Early release of tumor necrosis factor-alpha (TNF-α) during radiotherapy of thoracic cancers plays an important role in radiation pneumonitis, whose inhibition may provide lung radioprotection. We previously reported radiation inactivates Tristetraprolin (TTP), a negative regulator of TNF-α synthesis, which correlated with increased TNF-α release. However, the molecular events involved in radiation-induced TTP inactivation remain unclear. To determine if eliminating Ttp in mice resulted in a phenotypic response to radiation, Ttp-null mice lungs were exposed to a single dose of 15 Gy, and TNF-α release and lung inflammation were analyzed at different time points post-irradiation. Ttp-/- mice with elevated (9.5±0.6 fold) basal TNF-α showed further increase (12.2±0.9 fold, pacute lung inflammation within a week post-irradiation. Further studies using mouse lung macrophage (MH-S), human lung fibroblast (MRC-5), and exogenous human TTP overexpressing U2OS and HEK293 cells upon irradiation (a single dose of 4 Gy) promoted p38-mediated TTP phosphorylation at the serine 186 position, which primed it to be recognized by an ubiquitin ligase (E3), beta transducing repeat containing protein (β-TrCP), to promote polyubiquitination-mediated proteasomal degradation. Consequently, a serine 186 to alanine (SA) mutant of TTP was resistant to radiation-induced degradation. Similarly, either a p38 kinase inhibitor (SB203580), or siRNA-mediated β-TrCP knockdown, or overexpression of dominant negative Cullin1 mutants protected TTP from radiation-induced degradation. Consequently, SB203580 pretreatment blocked radiation-induced TNF-α release and radioprotected macrophages. Together, these data establish the involvement of the p38-βTrCP-TTP-TNFα signaling axis in radiation-induced lung inflammation and identified p38 inhibition as a possible lung radioprotection strategy.

  4. Unsteady aerodynamic forces estimation on a square cylinder by TR-PIV

    Science.gov (United States)

    Kurtulus, D. F.; Scarano, F.; David, L.

    2007-02-01

    The unsteady aerodynamic forces acting on a square cross-sectional cylinder are investigated by means of time-resolved particle image velocimetry (TR-PIV) at Reynolds number 4,900. The objective of the investigation is to prove the feasibility of non-intrusive force measurements around two-dimensional bodies. The PIV measurements performed at a rate of 1 kHz enable a time resolved (TR) description of the vortex shedding phenomenon occurring at 10 Hz and to follow the time evolution of vortex dominated wake. The instantaneous aerodynamic force coefficients are obtained from the integration of the force equations within a control volume enclosing the object. The required instantaneous pressure distribution is inferred making use of two physical models: Bernoulli relation is adopted in the potential slowly-evolving flow region; in the turbulent wake, the Navier Stokes equations are invoked to determine the pressure gradient spatial distribution, which integrated in space yields the pressure distribution. The spatial acceleration field is directly obtained from the temporal difference of the time-filtered velocity field. For a choice of the control volume approximately one model height away from the surface the contributions to the aerodynamic forces coming from the different terms of the force equation are individually examined. The convective term dominates the unsteady lift forces whereas the pressure term prevails for the drag. The temporal evolution of C L returns a clear periodic pattern in phase with the vortex shedding at a frequency of 10.1 Hz (Strouhal number St = 0.128) with oscillation amplitude of 0.9, whereas C D barely shows periodicity. The measurement uncertainties associated to the evaluation of all the terms in the force equation and especially in relation to TR-PIV measurements are discussed.

  5. Unsteady aerodynamic forces estimation on a square cylinder by TR-PIV

    Energy Technology Data Exchange (ETDEWEB)

    Kurtulus, D.F. [Laboratoire d' Etudes Aerodynamiques, ENSMA, Futuroscope Chasseneuil (France); Middle East Technical University, Aerospace Engineering Department, Ankara (Turkey); Scarano, F. [Delft University of Technology, Department of Aerospace Engineering, HS Delft (Netherlands); David, L. [Laboratoire d' Etudes Aerodynamiques, SP2MI Universite de Poitiers Boulevard Marie et Pierre Curie, BP30179, Futuroscope Chasseneuil (France)

    2007-02-15

    The unsteady aerodynamic forces acting on a square cross-sectional cylinder are investigated by means of time-resolved particle image velocimetry (TR-PIV) at Reynolds number 4,900. The objective of the investigation is to prove the feasibility of non-intrusive force measurements around two-dimensional bodies. The PIV measurements performed at a rate of 1 kHz enable a time resolved (TR) description of the vortex shedding phenomenon occurring at 10 Hz and to follow the time evolution of vortex dominated wake. The instantaneous aerodynamic force coefficients are obtained from the integration of the force equations within a control volume enclosing the object. The required instantaneous pressure distribution is inferred making use of two physical models: Bernoulli relation is adopted in the potential slowly-evolving flow region; in the turbulent wake, the Navier-Stokes equations are invoked to determine the pressure gradient spatial distribution, which integrated in space yields the pressure distribution. The spatial acceleration field is directly obtained from the temporal difference of the time-filtered velocity field. For a choice of the control volume approximately one model height away from the surface the contributions to the aerodynamic forces coming from the different terms of the force equation are individually examined. The convective term dominates the unsteady lift forces whereas the pressure term prevails for the drag. The temporal evolution of C{sub L} returns a clear periodic pattern in phase with the vortex shedding at a frequency of 10.1 Hz (Strouhal number St = 0.128) with oscillation amplitude of 0.9, whereas C{sub D} barely shows periodicity. The measurement uncertainties associated to the evaluation of all the terms in the force equation and especially in relation to TR-PIV measurements are discussed. (orig.)

  6. Desenvolvimento e produtividade do maracujazeiro-amarelo enxertado em três porta-enxertos

    Directory of Open Access Journals (Sweden)

    José Carlos Cavichioli

    2011-06-01

    Full Text Available O objetivo deste trabalho foi avaliar o desenvolvimento vegetativo e a produtividade do maracujazeiro-amarelo (Passiflora edulis Sims enxertado sobre três porta-enxertos em área sem histórico de morte prematura de plantas. O experimento foi conduzido no município de Adamantina-SP, no período de abril de 2006 a junho de 2007, adotando-se o delineamento em blocos ao acaso, em esquema fatorial 3 x 2 + 1 tratamento adicional, com quatro repetições. Os fatores avaliados foram três porta-enxertos: Passiflora edulis, P. alata e P. gibertii, em dois sistemas de enxertia, a hipocotiledonar e a convencional por garfagem tipo fenda cheia, e um tratamento adicional, sem enxertia. Utilizou-se como copa o maracujazeiro-amarelo (Passiflora edulis Sims. Avaliaram-se o diâmetro do caule do porta-enxerto, o diâmetro do caule do enxerto, o comprimento de entrenó, o comprimento dos ramos secundários, o número de ramos terciários, o número de frutos, a massa média de frutos, a produtividade e as fitomassas verde e seca das plantas. Observou-se que as três espécies estudadas podem ser utilizadas como porta-enxertos para o maracujazeiro-amarelo, com diferentes níveis de compatibilidade. P. edulis demonstrou maior compatibilidade como porta-enxerto por apresentar-se superior aos demais na maioria dos parâmetros analisados. Plantas enxertadas sobre P. gibertii apresentaram menor vigor, menor crescimento vegetativo, frutos com menor massa e menor produtividade. A enxertia hipocotiledonar resultou em maior massa média de frutos e maior produtividade no maracujazeiro-amarelo.

  7. High Efficiency, Digitally Calibrated TR Modules Enabling Lightweight SweepSAR Architectures for DESDynI-Class Radar Instruments Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Develop and demonstrate a next-generation digitally calibrated, highly scalable, L-band Transmit/Receive (TR) module to enable a precision beamforming SweepSAR...

  8. Evolução dos acidentes de trânsito em um grande centro urbano, 1991-2000

    OpenAIRE

    Oliveira,Zenaide Calazans de; Mota,Eduardo Luiz Andrade; Costa,Maria da Conceição N.

    2008-01-01

    Este estudo descreve a evolução dos acidentes de trânsito em Salvador, Bahia, Brasil, entre 1991 e 2000, utilizando-se dados do Departamento Estadual de Trânsito do Estado da Bahia. Calculou-se taxas globais dos acidentes de trânsito, vítimas e taxas padronizadas de mortalidade por habitante e por veículos, e comparou-se médias destes indicadores para antes (1991 a 1994) e após (1995 a 2000) a adoção de medidas de intervenção como o uso do cinto de segurança e o Código Nacional de Trânsito. A...

  9. Characteristics of a pressure sensitive touch sensor using a piezoelectric PVDF-TrFE/MoS2 stack

    International Nuclear Information System (INIS)

    Park, Woojin; Yang, Jin Ho; Kang, Chang Goo; Lee, Young Gon; Hwang, Hyeon Jun; Kang, Soo Cheol; Lee, Sang Kyung; Lee, Byoung Hun; Cho, Chunhum; Lim, Sung Kwan; Lee, Sangchul; Hong, Woong-Ki

    2013-01-01

    A new touch sensor device has been demonstrated with molybdenum disulfide (MoS 2 ) field effect transistors stacked with a piezoelectric polymer, polyvinylidene fluoride–trifluoroethylene (PVDF–TrFE). The performance of two device stack structures, metal/PVDF–TrFE/MoS 2 (MPM) and metal/PVDF–TrFE/Al 2 O 3 /MoS 2 (MPAM), were compared as a function of the thickness of PVDF–TrFE and Al 2 O 3 . The sensitivity of the touch sensor has been improved by two orders of magnitude by reducing the charge scattering and enhancing the passivation effects using a thin Al 2 O 3 interfacial layer. Reliable switching behavior has been demonstrated up to 120 touch press cycles. (paper)

  10. InGaP DHBT for High Efficiency L-band T/R Module, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — A fully monolithically integrated L-band T/R module using InGaP/GaAs-based HBTs (heterojunction bipolar transistors) for both the transmit and receive functions is...

  11. A Comparison of DSM-IV-TR and DSM-5 Diagnostic Classifications in the Clinical Diagnosis of Autistic Spectrum Disorder.

    Science.gov (United States)

    Yaylaci, Ferhat; Miral, Suha

    2017-01-01

    Aim of this study was to compare children diagnosed with Pervasive Developmental Disorder (PDD) according to DSM-IV-TR and DSM-5 diagnostic systems. One hundred fifty children aged between 3 and 15 years diagnosed with PDD by DSM-IV-TR were included. PDD symptoms were reviewed through psychiatric assessment based on DSM-IV-TR and DSM-5 criteria. Clinical severity was determined using Childhood Autism Rating Scale (CARS) and Autism Behavior Checklist (ABC). A statistically significant decrease (19.3 %) was detected in the diagnostic ratio with DSM-5. Age and symptom severity differed significantly between those who were and were not diagnosed with PDD using DSM-5. B4 criteria in DSM-5 was most common criterion. Results indicate that individuals diagnosed with PDD by DSM-IV-TR criteria may not be diagnosed using DSM-5 criteria.

  12. Gåsetrekket i Vesterålen og Nord-Trøndelag 2004

    DEFF Research Database (Denmark)

    Tombre, I.; Madsen, J.; Bakken, J.

    After several years of conflicts between spring staging geese and agricultural interests in Norway, 1 million NOK was provided by the authorities in order to carry out various alleviating initiatives in 2004. Hence, the Governors of Nord-Trøndelag and Nordland initiated a pilot project for the go...... neighbouring properties practice the same kind of action (scaring or free-areas). This will allow a more efficient scaring regime at the same time as the geese are able to fulfil their energetic needs on larger coherent and undisturbed areas...

  13. Hemorragia subendocárdica en fallecidos debido a accidentes de tránsito

    OpenAIRE

    Daisy Virgilí Jiménez; Yadira Leal Rivero; Daisy Ferrer Marrero

    1998-01-01

    En una revisión de 13 autopsias médico legales realizadas en el Instituto de Medicina Legal en casos de fallecidos por causas violentas, específicamente vinculados con hechos de tránsito, se encontró que 5 presentaban zonas de hemorragia subendocárdica a nivel de las paredes septal y libre del ventrículo izquierdo del corazón. El resultado de estos estudios es compatible con la hipótesis de la existencia de lesiones cardíacas secundarias a enfermedades no cardíacas, particularmente mediadas p...

  14. Pseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-U

    DEFF Research Database (Denmark)

    Davis, Matti; Hatzubai, Ada; Andersen, Jens S

    2002-01-01

    in the nucleus. Here we report the isolation of the major E3RS-associated protein, hnRNP-U, an abundant nuclear phosphoprotein. This protein occupies E3RS in a specific and stoichiometric manner, stabilizes the E3 component, and is likely responsible for its nuclear localization. hnRNP-U binding was abolished....... Consequently, hnRNP-U engages a highly neddylated active SCF(beta-TrCP), which dissociates in the presence of a high-affinity substrate, resulting in ubiquitination of the latter. Our study points to a novel regulatory mechanism, which secures the localization, stability, substrate binding threshold...

  15. Tráfico y trata de personas en España

    OpenAIRE

    López Sala, Ana María

    2013-01-01

    El objetivo de esta presentación es profundizar en los conceptos de tráfico y trata de personas. Comenzando en los años noventa, este documento señala la inconsistencia existente en las definiciones antes de 2000 y en los acuerdos alcanzados posteriormente para el desarrollo de definiciones operativas a partir de las cuáles realizar diagnósticos, articular sistemas de datos y desarrollar políticas de intervención. La segunda parte de la intervención se dirige a caracterizar cada uno de estos ...

  16. Desempenho de vacas Charolês e Nelore desterneiradas aos três ou sete meses

    Directory of Open Access Journals (Sweden)

    Restle João

    2001-01-01

    Full Text Available Foi avaliado o desempenho de vacas Charolês (C e Nelore (N, agrupadas em três classes de idade, jovens (3 e 4 anos, adultas (5 a 7 anos e velhas (8 ou mais anos, desmamadas aos três (precoce ou sete meses no outono (tradicional. O peso no outono das vacas desterneiradas aos três meses (T3 foi 45 kg superior ao das vacas com remoção do bezerro aos sete meses (T7. O estado corporal aos sete meses também foi melhor nas vacas do T3 (3,3 contra 2,1 pontos. Vacas do T3 apresentaram maior ganho de peso do parto ao final do período reprodutivo e apresentaram maiores porcentagem de cio (81 contra 51% e prenhez (67,2 contra 37,3% e menor intervalo do parto ao primeiro cio pós-parto (102 contra 114 dias que vacas do T7. Vacas adultas apresentaram melhor estado corporal aos sete meses e tiveram melhor desempenho reprodutivo do que vacas velhas e jovens. A diferença na porcentagem de prenhez entre o T3 e T7 foi mais evidente nas vacas jovens (42,11 contra 12,5% e velhas (51,72 contra 35,71% que nas adultas (62,50 contra 53,33%. Vacas C foram mais pesadas que as N, ao parto, aos três e sete meses pós-parto e apresentaram melhor estado corporal aos sete meses. O efeito do desmame precoce no desempenho reprodutivo foi mais evidente nas vacas C. A porcentagem de fêmeas prenhes nas C foi de 80,60% para o T3 e 41,90% para o T7, já nas N as porcentagens foram de 45,50 e 30,00%, respectivamente, para o T3 e T7. Nas vacas C, a produção de leite e a amamentação apresentaram efeito inibidor, sobre a reprodução, mais marcante que nas vacas N.

  17. Nietzsche e a jubilosa experiência trágica dos gregos

    Directory of Open Access Journals (Sweden)

    Renato Nunes Bittencourt

    2010-10-01

    Full Text Available Neste texto analisamos a interpretação de Nietzsche sobre o sentido existencial da experiência trágica realizada pelos antigos gregos na celebração estética e religiosa da Tragédia Ática, e de que modo tal experiência favorece a compreensão imanente e amoral da vida, suprimindo-se ainda qualquer tipo de depreciação moralista em relação ao real.

  18. Determinantes industriais da solidariedade transnacional: política intersindical global em três setores

    Directory of Open Access Journals (Sweden)

    Mark Anner

    2014-08-01

    Full Text Available Este artigo compara formas de transnacionalismo do trabalho em três setores: indústria automotiva; transporte marítimo; vestuário e indústria têxtil. Em cada caso, os sindicatos se envolvem em atividades transnacionais muito diferentes para reassumir o controle sobre o mercado de trabalho e a concorrência. Conforme as instituições de cooperação transnacional se tornam mais complexas, os sindicatos continuam a lutar com as tensões competitivas (trabalhador a trabalhador e sindicato a sindicato que variam de uma indústria para a outra.

  19. El derecho a migrar frontera del tráfico ilegal de migrantes

    OpenAIRE

    Faican Auquilla, Danilo Fabián

    2016-01-01

    Esta investigación se orienta a responder la siguiente pregunta: ¿De qué manera la regla penal de tráfico ilícito de migrantes limita el derecho a migrar previsto en la Constitución de la República de Ecuador? Para poder responder esta interrogante, el trabajo se ha dividido en tres capítulos. En el primer capítulo se ubica el alcance conceptual del derecho a migrar, para analizarlo como principio. Se determina las características, el titular del derecho, persona o ciudadano, para posteriorme...

  20. Desarrollo de un agente inteligente para el control del tráfico vehicular

    OpenAIRE

    Alayo Ávila, Jesús; Mera Dávila, Raúl; Rodríguez Sánchez, Claudia

    2014-01-01

    Esta investigación se basa en la tecnología de la visión computarizada de imágenes y videos para detectar, clasificar y dar seguimiento a objetos o eventos con la finalidad de entender una escena o contexto del mundo real. El objetivo es realizar el reconocimiento de vehículos automovilísticos que se encuentran en espera del cambio de color del semáforo en las vías de tránsito de la ciudad de Trujillo, para analizar e interpretar el congestionamiento vehicular y entregar una solución alterna...

  1. Trânsito religioso e reinvenções femininas do sagrado na modernidade

    Directory of Open Access Journals (Sweden)

    Sandra Duarte de Souza

    2009-05-01

    Full Text Available O trânsito religioso é indicador de que os “modelos oficiais e religião” têm sido substituídos, ou coexistem com  oferenciais religiosos cambiantes, respondendo à demanda dos sujeitos de fé. Os anseios de significação imediata dos sujeitos de fé encontram na “vagabundagem religiosa” sua atitude mais coerente. A vagabundagem semântica dos crentes infiéis é o elemento dinamizador do campo religioso moderno. No presente texto nos propomos a discutir o trânsito religioso de mulheres, suas motivações e as implicações dessa “andança religiosa” para a concepção que estas têm a respeito do sagrado. Para tanto nos utilizamos e dados de nossa pesquisa de campo realizada para a Universidade Católica de Goiás no ano 2000 em Alto Paraíso – GO, bem como de dados obtidos em pesquisa que realizamos para a Universidade Metodista de São Paulo na cidade de São Bernardo do Campo – SP em 2003, como parte do projeto intitulado: “Religiosidade caleidoscópica – nomadismo espiritual: implicações de gênero”. Os resultados da pesquisa indicaram um trânsito maior das mulheres por força das representações de gênero.Palavras-chave: Trânsito religioso; Secularização; Gênero.ABSTRACTReligious transit indicates that ‘official models of religion’ have been replaced, or coexist with mutable religious references, answering the believers’ demand. Their desire for immediate signification finds their most coherent attitude in ‘religious nomadism’. Unfaithful believers’ semantic nomadism is the dynamic element of modern religion. This text discusses women’s religious transit, their motivations and the implications of that ‘religious walk’ to their conception of the sacred. The date used are from a field research for the Universidade Católica de Goiás, developed in Alto Paraíso - State of Goiás, in 2000, and from a research for the Universidade Metodista de São Paulo, carried out in São Bernardo do

  2. Ferroelectric to paraelectric phase transition mechanism in poled PVDF-TrFE copolymer films

    Science.gov (United States)

    Pramanick, A.; Misture, S.; Osti, N. C.; Jalarvo, N.; Diallo, S. O.; Mamontov, E.

    2017-11-01

    Direct experimental insights into the structural and dynamical mechanisms for ferroelectric β to paraelectric α phase transition in a poled PVDF-TrFE copolymer is obtained from in situ x-ray diffraction and quasielastic neutron scattering measurements at high temperatures. It is observed that the β-to-α phase transition proceeds through two energetically distinct processes, which are identified here as the nucleation and growth of an intermediate γ phase with random skew linkages followed by a γ-to-α transition. The two energetically distinct microscopic processes can explain the stages of evolution for β-to-α phase transition observed from heat flow measurements.

  3. Prevención de accidentes de tráfico

    OpenAIRE

    Ocampo Suárez-Valdés, Gonzalo

    2010-01-01

    Uno de los objetivos prioritarios en los países industrializados consiste en lograr para los ciudadanos el mayor grado de bienestar posible. La prevención de accidentes de tráfico constituye una tarea importante dado su enorme impacto en nuestra sociedad actual, pues son conocidas las altas cifras de mortalidad y discapacidad derivadas de este tipo de accidentes en España. A pesar del alto índice de siniestros, en nuestro país se ha conseguido en los últimos años una disminución de un 31% de ...

  4. Prevención de los accidentes de tráfico infantiles

    OpenAIRE

    Rivera Menor, Estrella

    2003-01-01

    En España, aproximadamente el 3% de los muertos en accidente de tráfico es un niño de hasta 14 años. Sin embargo, con independencia de la importancia cuantitativa, es evidente la importancia cualitativa y sentimental que la pérdida de una vida que apenas comienza, o su sufrimiento, tiene sobre una sociedad que, de forma natural, acepta y asume como una de sus obligaciones, con entronque en sus valores primarios y por tanto más fuertemente arraigados, el salvaguardar y proteger a s...

  5. Reposição de nutrientes durante três cultivos de alface em hidroponia

    Directory of Open Access Journals (Sweden)

    Backes Fernanda Alice A.L.

    2003-01-01

    Full Text Available O experimento foi realizado em estufa plástica na UFSM, de agosto a novembro/99. Avaliou-se cinco formas de reposição de nutrientes na solução nutritiva com base na condutividade elétrica (CE, no sistema 'NFT' (Nutrient Film Technique e duas cultivares de alface: Regina e Deisy, cultivadas em bancadas de sustentação formadas por telhas de fibro-cimento revestidas com tinta betuminosa Neutrolâ. Foram dispostas 14 plantas por canal para cada repetição e uma cultivar em cada três canais, totalizando 84 plantas por bancada de produção. Comparou-se a eficiência de métodos de reposição de nutrientes na produção de alface, assim como a utilização da mesma solução, com reposição de nutrientes, durante três cultivos consecutivos. O delineamento experimental foi de blocos casualizados, com três repetições, em esquema fatorial 5x2. Os resultados demonstraram que o desempenho das cultivares avaliadas não foi influenciado pelos métodos de reposição de nutrientes. A ausência de reposição de nutrientes na solução nutritiva, durante um cultivo, permitiu maior produtividade da cultura, não se recomendando a reposição quando o objetivo for renovar a solução ao final do cultivo. As formas de reposição de nutrientes na solução nutritiva, durante o primeiro e segundo cultivos, não alteraram a produtividade da cultura em relação à renovação completa da solução nutritiva ao final do cultivo hidropônico. Para a reutilização de solução nutritiva, recomenda-se a reposição de nutrientes sempre que a CE diminuir 50% da inicial, possibilitando a produção por pelo menos três cultivos.

  6. Otite externa maligna por Pseudomonas aeruginosa: relato de três casos

    OpenAIRE

    Noujaim, Jorge El-Kadum; Rios-Gonçalves, Adrelirio José; Cunha, Rosamélia Queiroz da; Terra, Glaura Florim; Rozembaum, Ronaldo; Coral, Luiz Carlos; Abreu, Therezinha de Jesus

    1985-01-01

    Os autores apresentam três pacientes, de mais de 60 anos de idade, diabéticos de longa data, que tiveram achados clínicos, otológicos, do sistema nervoso e microbiológicos da otite externa maligna por Pseudomonas aeruginosa. O primeiro paciente, mulher de 62 anos de idade, teve na evolução clínica do processo importantes alterações de sistema nervoso, tais como meningite, de cujo LCR foi cultivada Pseudomonas aeruginosa, e envolvimento do 6º, 7º, 8º, 9º e 10º pares cranianos esquerdos; a desp...

  7. Modelo para la expansión de la capacidad de tráfico

    OpenAIRE

    Aldás Sánchez, Milton Rodrigo

    2015-01-01

    Tesis Doctoral leída en la Universidad Rey Juan Carlos de Madrid en 2015. Directores de la Tesis: David Ríos Insúa y Marco Javier Flores Calero En esta tesis se estudian los problemas del flujo de tráfico y la congestión vehicular, más concretamente en el casco urbano de la ciudad de Ambato. Estos problemas se han agudizado en los últimos tiempos debido al crecimiento poblacional, el aumento de entidades educativas, bancarias y comerciales y, especialmente, el incremento excesi...

  8. Três fórmulas para compreender "O suicídio" de Durkheim

    OpenAIRE

    Teixeira, Ricardo Rodrigues

    2002-01-01

    Trata-se de um ensaio de interpretação da sociologia durkheimiana, a partir de uma breve contextualização de seu pensamento no quadro de uma certa visão da modernidade e de uma particular leitura de sua obra "O Suicídio". Dividido em três partes, o texto procura explorar alguns sentidos desta Sociologia, ao mesmo tempo que expõe uma de suas possíveis aporias. This is an essay interpreting the sociology of Durkheim, based on a brief contextualization of his thoughts within the scope of a gi...

  9. Choline transport via choline transporter-like protein 1 in conditionally immortalized rat syncytiotrophoblast cell lines TR-TBT.

    Science.gov (United States)

    Lee, N-Y; Choi, H-M; Kang, Y-S

    2009-04-01

    Choline is an essential nutrient for phospholipids and acetylcholine biosynthesis in normal development of fetus. In the present study, we investigated the functional characteristics of choline transport system and inhibitory effect of cationic drugs on choline transport in rat conditionally immortalized syncytiotrophoblast cell line (TR-TBT). Choline transport was weakly Na(+) dependent and significantly influenced by extracellular pH and by membrane depolarization. The transport process of choline is saturable with Michaelis-Menten constants (K(m)) of 68microM and 130microM in TR-TBT 18d-1 and TR-TBT 18d-2 respectively. Choline uptake in the cells was inhibited by unlabeled choline and hemicholinium-3 as well as various organic cations including guanidine, amiloride and acetylcholine. However, the prototypical organic cation tetraethylammonium and cimetidine showed very little inhibitory effect of choline uptake in TR-TBT cells. RT-PCR revealed that choline transporter-like protein 1 (CTL1) and organic cation transporter 2 (OCT2) are expressed in TR-TBT cells. The transport properties of choline in TR-TBT cells were similar or identical to that of CTL1 but not OCT2. CTL1 was also detected in human placenta. In addition, several cationic drugs such as diphenhydramine and verapamil competitively inhibited choline uptake in TR-TBT 18d-1 with K(i) of 115microM and 55microM, respectively. Our results suggest that choline transport system, which has intermediate affinity and weakly Na(+) dependent, in TR-TBT seems to occur through a CTL1 and this system may have relevance with the uptake of pharmacologically important organic cation drugs.

  10. sA Comparison of DSM-IV-TR and DSM-5 Diagnostic Classifications in the Clinical Diagnosis of Autistic Spectrum Disorder

    Science.gov (United States)

    Yaylaci, Ferhat; Miral, Suha

    2017-01-01

    Aim of this study was to compare children diagnosed with Pervasive Developmental Disorder (PDD) according to DSM-IV-TR and DSM-5 diagnostic systems. One hundred fifty children aged between 3 and 15 years diagnosed with PDD by DSM-IV-TR were included. PDD symptoms were reviewed through psychiatric assessment based on DSM-IV-TR and DSM-5 criteria.…

  11. The development of a XEOL and TR XEOL detection system for the I18 microfocus beamline Diamond light source

    International Nuclear Information System (INIS)

    Taylor, R.P.; Finch, A.A.; Mosselmans, J.F.W.; Quinn, P.D.

    2013-01-01

    We describe the design and capabilities of a new Continuous Wave X-ray Excited Optical Luminescence (CW-XEOL) and Time Resolved X-ray Excited Optical Luminescence (TR-XEOL) facility on the I18 beamline at the DIAMOND light source, the UK national synchrotron facility. Experimental data from a suite of framework silicates are presented to illustrate the capabilities of the system. Experiments studied include simple (CW-XEOL) spectroscopy, (TR XEOL) lifetime experiments dose and dose rate dependence (CW-XEOL) experiments, spatial (TR XEOL) on heterogeneous sample, wavelength resolved (TR XEOL), Optically Derived X-ray Absorption Spectroscopy, (OD XAS). - Highlights: ► We describe the capabilities of a new CW-XEOL and TR-XEOL detection system for a hard X-ray beamline. ► We model TR XEOL with luminescence lifetimes from ∼25 ps to ∼400 ps from framework silicates. ► CW XEOL, 200–900 nm with a resolution of ∼0.9 nm is used to complete dose and dose rate experiments. ► Micro-beam high spatial resolution XEOL within X-ray excitation energies 2–20 keV.

  12. La metafilosofía de Eugenio Trías

    Directory of Open Access Journals (Sweden)

    Jonatan Caro Rey

    2016-01-01

    Full Text Available El artículo propone interpretar la metafilosofía de Eugenio Trías como un proyecto de liberación de la identidad (frente al subjetivismo paralelo a la liberación del discurso metafísico (frente a las actitudes antimetafísicas de la Teoría marxista —ortodoxa— de las ideologías y del positivismo lógico. En este intento mostraremos la íntima relación que con esta temática guardarían dos obras que no suelen asociarse al programa metafilosófico triasiano como son Filosofía y Carnaval (1970 (con su propuesta de la concepción de la identidad como profusión de máscaras y de la sociabilidad como Carnaval y La dispersión (1971 (desde su pensamiento fragmentario, aforístico. Ambas obras responderían a una misma estrategia caracterizada por el propio Trías de «mágica» y por nosotros (en un sentido que aclaramos al final del artículo de «cínica».

  13. Amyloid formation and disaggregation of α-synuclein and its tandem repeat (α-TR)

    International Nuclear Information System (INIS)

    Bae, Song Yi; Kim, Seulgi; Hwang, Heejin; Kim, Hyun-Kyung; Yoon, Hyun C.; Kim, Jae Ho; Lee, SangYoon; Kim, T. Doohun

    2010-01-01

    Research highlights: → Formation of the α-synuclein amyloid fibrils by [BIMbF 3 Im]. → Disaggregation of amyloid fibrils by epigallocatechin gallate (EGCG) and baicalein. → Amyloid formation of α-synuclein tandem repeat (α-TR). -- Abstract: The aggregation of α-synuclein is clearly related to the pathogenesis of Parkinson's disease. Therefore, detailed understanding of the mechanism of fibril formation is highly valuable for the development of clinical treatment and also of the diagnostic tools. Here, we have investigated the interaction of α-synuclein with ionic liquids by using several biochemical techniques including Thioflavin T assays and transmission electron microscopy (TEM). Our data shows a rapid formation of α-synuclein amyloid fibrils was stimulated by 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide [BIMbF 3 Im], and these fibrils could be disaggregated by polyphenols such as epigallocatechin gallate (EGCG) and baicalein. Furthermore, the effect of [BIMbF 3 Im] on the α-synuclein tandem repeat (α-TR) in the aggregation process was studied.

  14. Angst e sentimento (do trágico na moderna poesia de Língua Portuguesa

    Directory of Open Access Journals (Sweden)

    Ettore Finazzi-Agrò

    2008-12-01

    Full Text Available O intuito do ensaio é o de definir o lugar do trágico na moderna lírica de língua portuguesa (embora o discurso crítico seja centrado apenas na produção de Fernando Pessoa e de Carlos Drummond de Andrade. Espaço que se apresenta, na verdade, sem fronteiras certas e habitado por uma razão “bastarda” que tenta pensar de forma radical conflitos que “não se podem, porém se devem pensar em conjunto”. O ponto de partida é a retomada da análise de Heidegger sobre a “angústia” e o “tédio” que dão por um lado, ao sujeito, acesso a um conhecimento dolorido da sua origem recalcada, entregando-o, por outro lado, a uma condição impessoal, a um “fora” em relação à identidade em que o Eu se encontra apenas no seu banimento e na sua exceção.Palavras-chave: Trágico; Angústia; Tédio; Banimento; Fernando Pessoa; Carlos Drummond de Andrade.

  15. Detection of fast oscillating magnetic fields using dynamic multiple TR imaging and Fourier analysis.

    Directory of Open Access Journals (Sweden)

    Ki Hwan Kim

    Full Text Available Neuronal oscillations produce oscillating magnetic fields. There have been trials to detect neuronal oscillations using MRI, but the detectability in in vivo is still in debate. Major obstacles to detecting neuronal oscillations are (i weak amplitudes, (ii fast oscillations, which are faster than MRI temporal resolution, and (iii random frequencies and on/off intervals. In this study, we proposed a new approach for direct detection of weak and fast oscillating magnetic fields. The approach consists of (i dynamic acquisitions using multiple times to repeats (TRs and (ii an expanded frequency spectral analysis. Gradient echo echo-planar imaging was used to test the feasibility of the proposed approach with a phantom generating oscillating magnetic fields with various frequencies and amplitudes and random on/off intervals. The results showed that the proposed approach could precisely detect the weak and fast oscillating magnetic fields with random frequencies and on/off intervals. Complex and phase spectra showed reliable signals, while no meaningful signals were observed in magnitude spectra. A two-TR approach provided an absolute frequency spectrum above Nyquist sampling frequency pixel by pixel with no a priori target frequency information. The proposed dynamic multiple-TR imaging and Fourier analysis are promising for direct detection of neuronal oscillations and potentially applicable to any pulse sequences.

  16. P(VDF-TrFE) nanorod assemblies with anisotropic piezoelectric properties investigated by piezoelectric response microscopy

    Science.gov (United States)

    Chen, Xiaosui; Wang, Yunli; Cai, Kai; Bai, Yang; Bo, Shuhui; Guo, Dong

    2014-08-01

    Highly ordered assemblies of the copolymer of vinylidene fluoride and trifluoroethylene P(VDF-TrFE) nanorods with anisotropic piezoelectric response were fabricated on different substrates by using a template-free self-organization method. The significant difference in vertical and lateral piezoelectric responses of the nanorods in piezoresponse force microscopy (PFM) revealed that their molecular dipoles were preferentially oriented parallel to the substrate plane. In addition, dipole orientation distribution map in the nanorods was derived by analyzing the vertical and lateral PFM amplitude and phase images. Infrared reflection spectra further showed that the macromolecular backbones were oriented perpendicularly relative to the substrate. A flat-on lamellar structure and a confined crystallization of dewetted melt phase nanorod formation mechanism were proposed. The highly anisotropic piezoelectric response of the assemblies of nanorods may be promising for nanoscale devices for application in energy harvesting, etc. More importantly, the results demonstrated that self organization could be used for fabricating P(VDF-TrFE) nanostructures by controlling the surface energy of the substrates.

  17. Synthesis, physical and microwave absorption properties of Barium ferrite - P(VDF-TrFE) nanocomposites

    Science.gov (United States)

    Gutiérrez, Jon; Miren Gutiérrez Muto, Ane; Peña, Alazne; San Sebastián, Maria; Catarina Lopes, Ana; Lezama, Luis; Gil de Muro, Izaskun; Larrañaga, A.; Orue, I.

    2017-12-01

    We present results concerning the synthesis, magnetic, dielectric and microwave absorption properties of BaFe12O19 / P(VDF-TrFE) nanocomposites. First, barium ferrite nanopowders were prepared by the hydrothermal synthesis method. Structural and morphological properties of the prepared powders were investigated by X-ray diffraction (XRD) and transmission electron microscopy (TEM), showing as result a good quality spherical plus platelet-like shaped nanoparticles. Afterwards, composite films with filler nanoparticles of barium ferrite BaFe12O19 (BaFO, nominal 5-20 wt.%) dispersed within P(VDF-TrFE) acting as polymeric matrix have been prepared by solvent evaporation. Magnetic properties were examined by the vibrating sample magnetometry (VSM), and a direct comparison of results obtained for the composites respect to the pure nanopowder allow us to obtain the true nanofiller content value, different from the initially nominal one. Dielectric properties have been measured up to 2 MHz and show the typical behaviour of Maxwell-Wagner type interfacial polarization. From 10 kHz up, permittivity of the composites remains almost unchanged, with values that show a smooth increase as the %wt. of BaFe12O19 does. Finally, microwave absorption properties were analyzed by using ESR technique operating at X-band. All obtained results are discussed in terms of size and quantity of the composites BaFe12O19 filler nanoparticles.

  18. Immortalization of chicken preadipocytes by retroviral transduction of chicken TERT and TR.

    Directory of Open Access Journals (Sweden)

    Wei Wang

    Full Text Available The chicken is an important agricultural animal and model for developmental biology, immunology and virology. Excess fat accumulation continues to be a serious problem for the chicken industry. However, chicken adipogenesis and obesity have not been well investigated, because no chicken preadipocyte cell lines have been generated thus far. Here, we successfully generated two immortalized chicken preadipocyte cell lines through transduction of either chicken telomerase reverse transcriptase (chTERT alone or in combination with chicken telomerase RNA (chTR. Both of these cell lines have survived >100 population doublings in vitro, display high telomerase activity and have no sign of replicative senescence. Similar to primary chicken preadipocytes, these two cell lines display a fibroblast-like morphology, retain the capacity to differentiate into adipocytes, and do not display any signs of malignant transformation. Isoenzyme analysis and PCR-based analysis confirmed that these two cell lines are of chicken origin and are free from inter-species contamination. To our knowledge, this is the first report demonstrating the generation of immortal chicken cells by introduction of chTERT and chTR. Our established chicken preadipocyte cell lines show great promise as an in vitro model for the investigation of chicken adipogenesis, lipid metabolism, and obesity and its related diseases, and our results also provide clues for immortalizing other avian cell types.

  19. The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000.

    Science.gov (United States)

    Bairoch, A; Apweiler, R

    2000-01-01

    SWISS-PROT is a curated protein sequence database which strives to provide a high level of annotation (such as the description of the function of a protein, its domains structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases. Recent developments of the database include format and content enhancements, cross-references to additional databases, new documentation files and improvements to TrEMBL, a computer-annotated supplement to SWISS-PROT. TrEMBL consists of entries in SWISS-PROT-like format derived from the translation of all coding sequences (CDSs) in the EMBL Nucleotide Sequence Database, except the CDSs already included in SWISS-PROT. We also describe the Human Proteomics Initiative (HPI), a major project to annotate all known human sequences according to the quality standards of SWISS-PROT. SWISS-PROT is available at: http://www.expasy.ch/sprot/ and http://www.ebi.ac.uk/swissprot/

  20. Detection of fast oscillating magnetic fields using dynamic multiple TR imaging and Fourier analysis.

    Science.gov (United States)

    Kim, Ki Hwan; Heo, Hyo-Im; Park, Sung-Hong

    2018-01-01

    Neuronal oscillations produce oscillating magnetic fields. There have been trials to detect neuronal oscillations using MRI, but the detectability in in vivo is still in debate. Major obstacles to detecting neuronal oscillations are (i) weak amplitudes, (ii) fast oscillations, which are faster than MRI temporal resolution, and (iii) random frequencies and on/off intervals. In this study, we proposed a new approach for direct detection of weak and fast oscillating magnetic fields. The approach consists of (i) dynamic acquisitions using multiple times to repeats (TRs) and (ii) an expanded frequency spectral analysis. Gradient echo echo-planar imaging was used to test the feasibility of the proposed approach with a phantom generating oscillating magnetic fields with various frequencies and amplitudes and random on/off intervals. The results showed that the proposed approach could precisely detect the weak and fast oscillating magnetic fields with random frequencies and on/off intervals. Complex and phase spectra showed reliable signals, while no meaningful signals were observed in magnitude spectra. A two-TR approach provided an absolute frequency spectrum above Nyquist sampling frequency pixel by pixel with no a priori target frequency information. The proposed dynamic multiple-TR imaging and Fourier analysis are promising for direct detection of neuronal oscillations and potentially applicable to any pulse sequences.

  1. SoilTrEC: a global initiative on critical zone research and integration.

    Science.gov (United States)

    Menon, Manoj; Rousseva, Svetla; Nikolaidis, Nikolaos P; van Gaans, Pauline; Panagos, Panos; de Souza, Danielle Maia; Ragnarsdottir, Kristin Vala; Lair, Georg J; Weng, Liping; Bloem, Jaap; Kram, Pavel; Novak, Martin; Davidsdottir, Brynhildur; Gisladottir, Gudrun; Robinson, David A; Reynolds, Brian; White, Tim; Lundin, Lars; Zhang, Bin; Duffy, Christopher; Bernasconi, Stefano M; de Ruiter, Peter; Blum, Winfried E H; Banwart, Steven A

    2014-02-01

    Soil is a complex natural resource that is considered non-renewable in policy frameworks, and it plays a key role in maintaining a variety of ecosystem services (ES) and life-sustaining material cycles within the Earth's Critical Zone (CZ). However, currently, the ability of soil to deliver these services is being drastically reduced in many locations, and global loss of soil ecosystem services is estimated to increase each year as a result of many different threats, such as erosion and soil carbon loss. The European Union Thematic Strategy for Soil Protection alerts policy makers of the need to protect soil and proposes measures to mitigate soil degradation. In this context, the European Commission-funded research project on Soil Transformations in European Catchments (SoilTrEC) aims to quantify the processes that deliver soil ecosystem services in the Earth's Critical Zone and to quantify the impacts of environmental change on key soil functions. This is achieved by integrating the research results into decision-support tools and applying methods of economic valuation to soil ecosystem services. In this paper, we provide an overview of the SoilTrEC project, its organization, partnerships and implementation.

  2. Local mechanical and electromechanical properties of the P(VDF-TrFE)-graphene oxide thin films

    Science.gov (United States)

    Silibin, M. V.; Bystrov, V. S.; Karpinsky, D. V.; Nasani, N.; Goncalves, G.; Gavrilin, I. M.; Solnyshkin, A. V.; Marques, P. A. A. P.; Singh, Budhendra; Bdikin, I. K.

    2017-11-01

    Recently, many organic materials, including carbon materials such as carbon nanotubes (CNTs) and graphene (single-walled carbon sheet structure) were studied in order to improve their mechanical and electrical properties. In particular, copolymers of poly (vinylidene fluoride) and poly trifluoroethylene [P(VDF-TrFE)] are promising materials, which can be used as probes, sensors, actuators, etc. Composite thin film of the copolymer P(VDF-TrFE) with graphene oxide (GO) were prepared by spin coating. The obtained films were investigated using piezoresponse force microscopy (PFM). The switching behavior, piezoelectric response, dielectric permittivity and mechanical properties of the films were found to depend on the presence of GO. For understanding the mechanism of piezoresponse evolution of the composite we used models of PVDF chain, its behavior in electrical field and computed the data for piezoelectric coefficients using HyperChem software. The summarized models of graphene oxide based on graphene layer from 96 carbon atoms C: with oxygen and OH groups and with COOH groups arranged by hydrogen were used for PVDF/Graphene oxide complex: 1) with H-side (hydrogen atom) connected from PVDF to graphene oxide, 2) with F-side (fluorine atom) connected from PVDF graphene oxide and 3) Graphene Oxide/PVDF with both sides (sandwich type). Experimental results qualitatively correlate with those obtained in the calculations.

  3. Sequential least-square reconstruction of instantaneous pressure field around a body from TR-PIV

    Science.gov (United States)

    Jeon, Young Jin; Gomit, G.; Earl, T.; Chatellier, L.; David, L.

    2018-02-01

    A procedure is introduced to obtain an instantaneous pressure field around a wing from time-resolved particle image velocimetry (TR-PIV) and particle image accelerometry (PIA). The instantaneous fields of velocity and material acceleration are provided by the recently introduced multi-frame PIV method, fluid trajectory evaluation based on ensemble-averaged cross-correlation (FTEE). The integration domain is divided into several subdomains in accordance with the local reliability. The near-edge and near-body regions are determined based on the recorded image of the wing. The instantaneous wake region is assigned by a combination of a self-defined criterion and binary morphological processes. The pressure is reconstructed from a minimization process of the difference between measured and reconstructed pressure gradients in a least-square sense. This is solved sequentially according to a decreasing order of reliability of each subdomain to prevent a propagation of error from the less reliable near-body region to the free-stream. The present procedure is numerically assessed by synthetically generated 2D particle images based on a numerical simulation. Volumetric pressure fields are then evaluated from tomographic TR-PIV of a flow around a 30-degree-inclined NACA0015 airfoil. A possibility of using a different scheme to evaluate material acceleration for a specific subdomain is presented. Moreover, this 3D application allows the investigation of the effect of the third component of the pressure gradient by which the wake region seems to be affected.

  4. Influência de três modos de fotopolimerização sobre a microdureza de três resinas compostas

    Directory of Open Access Journals (Sweden)

    Andréa Cristina Schneider

    2016-01-01

    Full Text Available Resumo A adequada fotopolimerização das resinas compostas é fundamental para obtenção de uma boa dureza capaz de resistir aos esforços mastigatórios. Assim, o objetivo deste estudo foi avaliar a influência das técnicas de fotopolimerização - Convencional (CONV, Soft-start (SS e Pulso atrasado (PA na microdureza Knoop de três resinas compostas. Para a confecção dos corpos-de-prova foram utilizadas as resinas compostas Filtek Z350 (3M ESPE, Empress Direct (IvoclarVivadent e P90 (3M ESPE. Foram obtidos nove grupos experimentais em função da técnica de polimerização e resina composta. Vinte e quatro horas após a fotopolimerização foi realizado o teste de microdureza Knoop nas superfícies de base e topo de cada corpo-de-prova. Assim, os valores obtidos foram submetidos ao teste de Kruskall Wallis, seguido do teste de Dunn, p < 0,05. A eficácia da polimerização na superfície de topo das resinas compostas testadas não foi afetada pelos diferentes modos de polimerização. A resina composta Empress Direct apresentou os mais baixos valores de dureza para todos os modos de polimerização quando comparada às demais resinas compostas avaliadas.

  5. Tumores primarios malignos de tráquea y bronquios principales

    Directory of Open Access Journals (Sweden)

    Edelberto Fuentes Valdés

    2002-12-01

    Full Text Available Los tumores de la tráquea y los bronquios principales son raros, por lo que no existe experiencia importante en el tratamiento de éstos. Los tipos histológicos más frecuentes son el carcinoma adenoideo quístico y el carcinoma de células escamosas. En nuestro caso estos tipos histológicos se presentaron en 2 pacientes respectivamente. El carcinoma mucoepidermoide fue el diagnóstico en otros 2 enfermos y el leiomiosarcoma de tráquea en un caso. La resección quirúrgica fue el tratamiento de elección con resección de carina en 3 enfermos, neumonectomía en 1 y resección de tráquea cervical en 3. La radioterapia adyuvante se utilizó en los cilindromas, los carcinomas de células escamosas y los tumores mucoepidermoides. Solo 1 de 7 pacientes mostró complicaciones y no hubo mortalidad posoperatoria. La mayor supervivencia ha sido de 172 meses en el caso del leiomiosarcoma. Una enferma con un cilindroma falleció a los 74 meses de operada y los 2 enfermos con tumores epidermoides de bronquio principal fallecieron 13 y 15 meses después de su operación, todos por enfermedad metastásicaAs the trachea and primary bronchus tumors are rare, there is no an important experience in their treatment. The most frequent histological types are the adenoid cystic carcinoma and the squamous cell carcinoma. In our case, these histological cases were observed in 2 patients, respectively. The mucoepidermoid carcinoma was diagnosed in 2 other patients and the tracheal leiomyosarcoma in one case. Surgical resection was the election treatment with carina resection, in 3 patients; pneumonectomy, in 1; and cervical trachea resection, in 3. Adjuvant radiotherapy was used in cylindromas, squamous cell carcinomas and mucoepidermoid tumors. Only 1 of 7 patients had complications. There was no postoperative mortality. The highest survival has been of 172 months in the leiomyosarcoma. A female patient with a cylindroma died 74 months after the operation, whereas

  6. O enfrentamento ao tráfico de pessoas no âmbito do Mercosul

    Directory of Open Access Journals (Sweden)

    Mário Lúcio Quintão Soares

    2011-12-01

    Full Text Available Human trafficking is a serious problemthat, in its various forms – sexual exploitation,forced labor and removal of organs – isin the form of transnational organized crime,affecting every country in the world. Apparently,the increasing political integration, economicand social activity is one way to attempt to minimizethe human trafficking. In the case of theSouthern Cone Common Market – Mercosur,efforts have been made to both by its States Parties(Argentina, Brazil, Paraguay and Uruguay,as they ratified the Palermo Protocol. Within thisframework, this study aimed to examine the measuresadopted within Mercosur in a way to protectand promote the rights of trafficked persons.To accomplish this work, the emphasis has beendescriptive and analytical study, by means of literatureand documents. Note that only Brazil andArgentina have adopted specific policies on traffickingin persons. Given this, it was found thatthe States Parties of Mercosur develop actions toprotect and promote human rights of traffickedpersons, not counting even some specific publicpolicy.O tráfico de pessoas é um problema graveque, nas suas diversas modalidades – exploraçãosexual, trabalhos forçados e remoção de órgãos –constitui-se em forma de crime organizado transnacional,atingindo todos os países do mundo. Ao queparece, a crescente integração política, econômica esocial constitui caminho para uma tentativa de minimizaçãodo tráfico de pessoas. Em se tratando deMercado Comum do Cone Sul – Mercosul, esforçostêm sido envidados para tanto por parte dos seus EstadosPartes (Argentina, Brasil, Paraguai e Uruguai,pois esses países ratificaram o Protocolo de Palermo.Nesse marco, esta pesquisa teve por objetivo analisaras medidas adotadas no âmbito do Mercosul para aproteção e promoção dos direitos das pessoas traficadas.Para a concretização deste trabalho, privilegiou-se o estudo descritivo e analítico, por meio depesquisa bibliográfica e

  7. Novel treatment option for MUC16-positive malignancies with the targeted TRAIL-based fusion protein Meso-TR3.

    Science.gov (United States)

    Garg, Gunjal; Gibbs, Jesse; Belt, Brian; Powell, Matthew A; Mutch, David G; Goedegebuure, Peter; Collins, Lynne; Piwnica-Worms, David; Hawkins, William G; Spitzer, Dirk

    2014-01-21

    The targeted delivery of cancer therapeutics represents an ongoing challenge in the field of drug development. TRAIL is a promising cancer drug but its activity profile could benefit from a cancer-selective delivery mechanism, which would reduce potential side effects and increase treatment efficiencies. We recently developed the novel TRAIL-based drug platform TR3, a genetically fused trimer with the capacity for further molecular modifications such as the addition of tumor-directed targeting moieties. MUC16 (CA125) is a well characterized biomarker in several human malignancies including ovarian, pancreatic and breast cancer. Mesothelin is known to interact with MUC16 with high affinity. In order to deliver TR3 selectively to MUC16-expressing cancers, we investigated the possibility of targeted TR3 delivery employing the high affinity mesothelin/MUC16 ligand/receptor interaction. Using genetic engineering, we designed the novel cancer drug Meso-TR3, a fusion protein between native mesothelin and TR3. The recombinant proteins were produced with mammalian HEK293T cells. Meso-TR3 was characterized for binding selectivity and killing efficacy against MUC16-positive cancer cells and controls that lack MUC16 expression. Drug efficacy experiments were performed in vitro and in vivo employing an intraperitoneal xenograft mouse model of ovarian cancer. Similar to soluble mesothelin itself, the strong MUC16 binding property was retained in the Meso-TR3 fusion protein. The high affinity ligand/receptor interaction was associated with a selective accumulation of the cancer drug on MUC16-expressing cancer targets and directly correlated with increased killing activity in vitro and in a xenograft mouse model of ovarian cancer. The relevance of the mesothelin/MUC16 interaction for attaching Meso-TR3 to the cancer cells was verified by competitive blocking experiments using soluble mesothelin. Mechanistic studies using soluble DR5-Fc and caspase blocking assays confirmed

  8. Novel treatment option for MUC16-positive malignancies with the targeted TRAIL-based fusion protein Meso-TR3

    International Nuclear Information System (INIS)

    Garg, Gunjal; Spitzer, Dirk; Gibbs, Jesse; Belt, Brian; Powell, Matthew A; Mutch, David G; Goedegebuure, Peter; Collins, Lynne; Piwnica-Worms, David; Hawkins, William G

    2014-01-01

    The targeted delivery of cancer therapeutics represents an ongoing challenge in the field of drug development. TRAIL is a promising cancer drug but its activity profile could benefit from a cancer-selective delivery mechanism, which would reduce potential side effects and increase treatment efficiencies. We recently developed the novel TRAIL-based drug platform TR3, a genetically fused trimer with the capacity for further molecular modifications such as the addition of tumor-directed targeting moieties. MUC16 (CA125) is a well characterized biomarker in several human malignancies including ovarian, pancreatic and breast cancer. Mesothelin is known to interact with MUC16 with high affinity. In order to deliver TR3 selectively to MUC16-expressing cancers, we investigated the possibility of targeted TR3 delivery employing the high affinity mesothelin/MUC16 ligand/receptor interaction. Using genetic engineering, we designed the novel cancer drug Meso-TR3, a fusion protein between native mesothelin and TR3. The recombinant proteins were produced with mammalian HEK293T cells. Meso-TR3 was characterized for binding selectivity and killing efficacy against MUC16-positive cancer cells and controls that lack MUC16 expression. Drug efficacy experiments were performed in vitro and in vivo employing an intraperitoneal xenograft mouse model of ovarian cancer. Similar to soluble mesothelin itself, the strong MUC16 binding property was retained in the Meso-TR3 fusion protein. The high affinity ligand/receptor interaction was associated with a selective accumulation of the cancer drug on MUC16-expressing cancer targets and directly correlated with increased killing activity in vitro and in a xenograft mouse model of ovarian cancer. The relevance of the mesothelin/MUC16 interaction for attaching Meso-TR3 to the cancer cells was verified by competitive blocking experiments using soluble mesothelin. Mechanistic studies using soluble DR5-Fc and caspase blocking assays confirmed

  9. Sistemas agrosilvopastoriles: una alternativa de desarrollo rural sustentable para el trópico mexicano

    Directory of Open Access Journals (Sweden)

    M. Á. Musálem

    2002-01-01

    Full Text Available Se presenta algunas definiciones de agroforestería, los conceptos y características y la importancia y perspectivas en México. Además, se describe brevemente algunos de los sistemas más importantes en las regiones templadas, tropicales y áridas de México. Así mismo, se ejemplifica con algunos esquemas producto de la investigación reciente aplicados en la región tropical de Puebla y Veracruz y en la zona templada del Estado de México. Así mismo, se enfatiza la aplicación de los sistemas agrosilvopastoriles en las fincas de los pequeños productores en el trópico de México.

  10. Dose assessment around TR-2 reactor due to maximum credible accident

    International Nuclear Information System (INIS)

    Turgut, M. H.; Adalioglu, U.; Aytekin, A.

    2001-01-01

    The revision of safety analysis report of TR-2 research reactor had been initiated in 1995. The whole accident analysis and accepted scenario for maximum credible accident has been revised according to the new safety concepts and the impact to be given to the environment due to this scenario has been assessed. This paper comprises all results of these calculations. The accepted maximum credible accident scenario is the partial blockage of the whole reactor core which resulted in the release of 25% of the core inventory. The DOSER code which uses very conservative modelling of atmospheric distributions were modified for the assessment calculations. Pasquill conditions based on the local weather observations, topography, and building affects were considered. The thyroid and whole body doses for 16 sectors and up to 10 km of distance around CNAEM were obtained. Release models were puff and a prolonged one of two hours of duration. Release fractions for the active isotopes were chosen from literature which were realistic

  11. Klippel–Trénaunay Syndrome – A Very Rare and Interesting Syndrome

    Directory of Open Access Journals (Sweden)

    Deepak Sharma

    2015-01-01

    Full Text Available Klippel–Trénaunay syndrome (KTS or KT is an infrequently seen dermatological syndrome, which is often viewed as a triad of vascular malformation (capillary malformations or port-wine brands, venous varicosity, and soft tissue and/or bony hypertrophy. We report a case of a 12-year-old male who presented to us with the symptoms of varicose plaques over both lower limbs and was diagnosed as a case of KTS. Management is normally conservative and includes stockings for compression of the branches to reduce edema because of chronic venous insufficiency; modern devices that cause on and off pneumatic compression; and rarely, surgical correction of varicose veins with lifelong follow-up. The orthopedic abnormalities are treated with epiphysiodesis in order to prevent (stop overgrowing of limb and correction of bone deformity.

  12. T/R Multi-Chip MMIC Modules for 150 GHz

    Science.gov (United States)

    Samoska, Lorene A.; Pukala, David M.; Soria, Mary M.; Sadowy, Gregory A.

    2009-01-01

    Modules containing multiple monolithic microwave integrated-circuit (MMIC) chips have been built as prototypes of transmitting/receiving (T/R) modules for millimeter-wavelength radar systems, including phased-array radar systems to be used for diverse purposes that could include guidance and avoidance of hazards for landing spacecraft, imaging systems for detecting hidden weapons, and hazard-avoidance systems for automobiles. Whereas prior landing radar systems have operated at frequencies around 35 GHz, the integrated circuits in this module operate in a frequency band centered at about 150 GHz. The higher frequency (and, hence, shorter wavelength), is expected to make it possible to obtain finer spatial resolution while also using smaller antennas and thereby reducing the sizes and masses of the affected systems.

  13. Três Durações: Nelson, Glauber e Bressane

    Directory of Open Access Journals (Sweden)

    Alexandre Rocha da Silva

    2011-01-01

    Full Text Available Três Durações: Glauber, Bressane e Nelson identifica formas de brasilidade expressas pelo Cinema Novo. Recupera de Bergson os conceitos de  imagem-lembrança,  imagem-ação eduração para expressar indícios de brasilidade que ora se como identidade nacional ora como devir de um outro país imaginado pelo cinema. O Cinema Novo oferece formas de expressão remidiatizadas em que se visibilizam as estratégias micropolíticas que configuram a nacionalidade brasileira não mais somente como identidade, mas, sobretudo como memória.

  14. The SWISS-PROT protein sequence data bank and its supplement TrEMBL.

    Science.gov (United States)

    Bairoch, A; Apweiler, R

    1997-01-01

    SWISS-PROT is a curated protein sequence database which strives to provide a high level of annotations (such as the description of the function of a protein, structure of its domains, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases. Recent developments of the database include: an increase in the number and scope of model organisms; cross-references to two additional databases; a variety of new documentation files and the creation of TrEMBL, a computer annotated supplement to SWISS-PROT. This supplement consists of entries in SWISS-PROT-like format derived from the translation of all coding sequences (CDS) in the EMBL nucleotide sequence database, except the CDS already included in SWISS-PROT. PMID:9016499

  15. A TR-UWB Downconversion Autocorrelation Receiver for Wireless Body Area Network

    Directory of Open Access Journals (Sweden)

    Islam SMRiazul

    2009-01-01

    Full Text Available Low power UWB receiver architecture is proposed for a Wireless Body Area Network (WBAN. This receiving technology is a synergy of existing downconversion-based narrowband rejection mechanism in RF front end and signal processing in frequency domain. Frequency components of converted and filtered UWB pulses are separated into real and imaginary parts, independently correlated and effectively combined to achieve an improved output Signal to noise ratio (SNR. An extensive mathematical analysis has been performed to formulate the close-form expressions for SNRs in order to compare system performances toward favorable BER under BPSK modulation scheme. Analysis shows that optimal rotation of coordination plays an important role for the enhancement of receiving SNR which is further confirmed by computer simulation. A wide range of link level simulation (LLS urges that the proposed system is more power efficient in higher-order modulation (HOM schemes. Transmitted Reference (TR scheme has been considered as the basis for wideband communication.

  16. Manual de importaciones con tránsito aduanero a la ciudad de Cuenca

    OpenAIRE

    Códova L., Cristina; Castillo S., Andrea

    2010-01-01

    El trabajo presenta la elaboración de un Manual de Importaciones con Tránsito Aduanero a la ciudad de Cuenca cuyo objetivo es informar y guiar al importador en los procesos a seguir para la importación de su mercadería. El estudio se basa en la investigación bibliográfica y de campo. Del análisis de los procesos se concluye que el principal problema es la mala emisión de los documentos de importación, así como la falta de conocimiento del proceso de importación y de movilización y nacionaliza...

  17. La comprensión aristotélica de lo trágico

    OpenAIRE

    Mejía Mosquera, Juan Fernando; Pontificia Universidad Javeriana

    2014-01-01

    Este trabajo intenta presentar, de un modo sencillo, puntos de referencia desde los cuales Aristóteles aborda el problema de lo trágico en la Poética. En él se registran en primer lugar, las distiniciones que le permiten hablar de un género poético noble -en el cual se ubica la tragedia como especie-, y también las que hacen posible hablar de un modo dramático de imitación. En segundo lugar se analiza la definición de tragedia que remite a su vez a un intento de definición de la mimesis arist...

  18. Mapping visible-light direct optical excitations of a topological insulator via trARPES

    Science.gov (United States)

    Soifer, Hadas; Sobota, J. A.; Gauthier, A. V.; Yang, S.-L.; Xiong, H.; Pfau, H.; Rotundo, C.; Kirchmann, P. S.; Shen, Z. X.

    Topological insulators have been in the focus of condensed-matter research in recent years. In particular, much effort was dedicated to optically manipulate the spin-textured electrons in the topological surface states. In this work we use time- and angle-resolved photoemission spectroscopy (trARPES) to induce and probe direct optical transitions to unoccupied states of the topological insulator Bi2Se3. We tuned the excitation wavelength in the visible regime, and studied the ultrafast dynamics of the electronic excitation and decay. The detailed time-resolved data allowed us to clearly resolve different contributions to the excited population. We used a time-mapping procedure to identify the initial states, and observed processes involving topological surface states as either the initial or excited state. Our results reveal the intricacies of photo-excitations of topological surface states, and establish pump-tuning in the visible regime as a tool for optical control of topological insulators.

  19. Defining mental disorder when it really counts: DSM-IV-TR and SVP/SDP statutes.

    Science.gov (United States)

    Frances, Allen; Sreenivasan, Shoba; Weinberger, Linda E

    2008-01-01

    Civil commitment under the sexually violent predator (SVP) statutes requires the presence of a statutorily defined diagnosed mental disorder linked to sexual offending. As a consequence of broad statutory definitions and ambiguously written court decisions, a bright line separating an SVP mental disorder from ordinary criminal behavior is difficult to draw. Some forensic evaluators reject whole categories of DSM-IV-TR (Diagnostic and Statistical Manual of Mental Disorders: Text Revision) diagnoses as qualifying disorders (e.g., personality and substance abuse disorders), while others debate whether recurrent rape constitutes a paraphilic disorder. We argue that the ramifications of the SVP process, in representing both the balancing of public safety and the protection of an individual's right to liberty, demand that decisions about what is a legally defined mental disorder not be made in an arbitrary and idiosyncratic manner. Greater clarity and standardization must come from both sides: the legalists who interpret the law and the clinicians who apply and work under it.

  20. Tráfico internacional de armas na fronteira Brasil/Bolívia

    OpenAIRE

    Cossul, Naiane Inez

    2015-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Sócio-Econômico, Programa de Pós-Graduação em Relações Internacionais, Florianópolis, 2015. Essa dissertação objetiva entender como o tráfico internacional de armas pequenas e leves na fronteira Brasil/Bolívia aumenta a insegurança nesses Estados. Para isso, pontua-se os fluxos domésticos e regionais de armas pequenas e leves por meio da análise macro do comércio legítimo na região, tendo o Brasil, devido à sua relevan...

  1. Sensitivity of diamond-capped impedance transducer to Tröger's base derivative.

    Science.gov (United States)

    Stehlik, Stepan; Izak, Tibor; Kromka, Alexander; Dolenský, Bohumil; Havlík, Martin; Rezek, Bohuslav

    2012-08-01

    Sensitivity of an intrinsic nanocrystalline diamond (NCD) layer to naphthalene Tröger's base derivative decorated with pyrrole groups (TBPyr) was characterized by impedance spectroscopy. The transducer was made of Au interdigitated electrodes (IDE) with 50 μm spacing on alumina substrate which were capped with the NCD layer. The NCD-capped transducer with H-termination was able to electrically distinguish TBPyr molecules (the change of surface resistance within 30-60 kΩ) adsorbed from methanol in concentrations of 0.04 mg/mL to 40 mg/mL. An exponential decay of the surface resistance with time was observed and attributed to the readsorption of air moisture after methanol evaporation. After surface oxidation the NCD cap layer did not show any leakage due to NCD grain boundaries. We analyzed electronic transport in the transducer and propose a model for the sensing mechanism based on surface ion replacement.

  2. Research on Fault Rate Prediction Method of T/R Component

    Science.gov (United States)

    Hou, Xiaodong; Yang, Jiangping; Bi, Zengjun; Zhang, Yu

    2017-07-01

    T/R component is an important part of the large phased array radar antenna array, because of its large numbers, high fault rate, it has important significance for fault prediction. Aiming at the problems of traditional grey model GM(1,1) in practical operation, the discrete grey model is established based on the original model in this paper, and the optimization factor is introduced to optimize the background value, and the linear form of the prediction model is added, the improved discrete grey model of linear regression is proposed, finally, an example is simulated and compared with other models. The results show that the method proposed in this paper has higher accuracy and the solution is simple and the application scope is more extensive.

  3. Perspectivas de género en las condenas por tráfico de drogas

    Directory of Open Access Journals (Sweden)

    Luz M. Puente Aba

    2012-12-01

    Full Text Available This article pretends to examine sentences for drug trafficking from a gender perspective. An in-depth analysis of sentences and prison statistics from this point of view reveals that women are most affected by this repressive policy. The most remarkable fact is that while the number of convicted women in general is low, a large percentage of female offenders’ sentences are related to drug offences, thus representing a higher percentage in this group than in the male group. Yet if we analyze the prison population from a gender perspective, the results are even more striking: whereas women make up an insignificant percentage of the total, they nonetheless represent a large part of the total number of sentences for drug trafficking. Furthermore, a study of the characteristics of women sentenced for these crimes allows us to trace a specific profile for this group, which in turn provides an insight into why women are the main victims of the repressive drug policy, and the consequences they face. It will be analyzed whether penal treatment contributes to an excessive representation of the feminine gender in prisons; which gender sectors are particularly affected; and how we could find the causes and consequences of this situation. To conclude, new ways to solve this problem are suggested: reconsidering criminal policy on drugs, or strengthening alternatives to prison and different measures to support people serving sentences in prison. Este trabajo pretende analizar las condenas por tráfico de drogas desde una perspectiva de género. Partiendo de las estadísticas relativas al número y tipología de condenas por delitos, y asimismo de las estadísticas relativas a la población de los centros penitenciarios, se puede extraer que las mujeres son las más afectadas por la política penal en materia de tráfico de drogas, de carácter marcadamente represivo, puesto que suponen un porcentaje ínfimo de la población penitenciaria, y en cambio

  4. Flow field characteristics of impinging sweeping jets: TR-PIV measurement

    Science.gov (United States)

    Wen, Xin; Peng, Di; Liu, Yingzheng; Tang, Hui

    2017-11-01

    Influence of Reynolds number of sweeping jets on its impinging flow fields was extensively investigated in a water tank. Toward this end, a fluidic oscillator was specially designed to produce spatially sweeping jets which imping on a flat plate. Six Reynolds numbers were tested by controlling the supply flow rate of the fluidic oscillator. Impinging flow fields were captured by time-resolved Particle Image Velocimetry (TR-PIV) measurement. Reference signals were extracted from the flow fields for phase reconstruction. The oscillating flow fields with super-harmonic frequency at different regions were discussed in term of the phase-averaged velocity, vorticity and turbulent velocity. Dynamic mode decomposition (DMD) was used to capture the most-energetic flow patterns with distinct frequencies. By projecting the phase-averaged flow fields onto a reduced basis of DMD modes, the phase correlation between the distinct flow patterns were analyzed under different Reynolds numbers.

  5. Tráfico sexual de mulheres: Representações sobre ilegalidade e vitimação

    Directory of Open Access Journals (Sweden)

    Boaventura de Sousa Santos

    2012-10-01

    Full Text Available O tráfico de seres humanos em geral, e de mulheres em particular, vem suscitando um interesse crescente por parte dos Estados, das instâncias internacionais, das organizações não‑governamentais, dos meios de comunicação social e, também, por parte da academia. A maior visibilidade conferida a este fenómeno tem‑se traduzido, a nível nacional e internacional, em políticas de combate e prevenção cuja eficácia é discutível. Para tal contribui não apenas um desconhecimento das especificidades que o tráfico de mulheres assume, como também objectivos outros que podem estar na base da construção de tais políticas e que dificilmente vão ao encontro daquilo que são as subjectividades e expectativas das mulheres traficadas. Neste artigo reflectimos sobre algumas das questões emergentes e ausentes no enquadramento legal do tráfico sexual de mulheres, recorrendo à realidade empírica do tráfico sexual em Portugal analisada no estudo Tráfico de mulheres em Portugal para fins de exploração sexual.1

  6. Vaccinia virus protein A49 activates Wnt signalling by targetting the E3 ligase β-TrCP

    Science.gov (United States)

    Maluquer de Motes, Carlos; Smith, Geoffrey L.

    2017-01-01

    Vaccinia virus (VACV) encodes multiple proteins inhibiting the NF-κB signalling pathway. One of these, A49, targets the E3 ubiquitin ligase β-TrCP, which is responsible for the ubiquitylation and consequential proteosomal degradation of IκBα and the release of the NF-κB heterodimer. β-TrCP is a pleiotropic enzyme ubiquitylating multiple cellular substrates, including the transcriptional activator β-catenin. Here we demonstrate that A49 can activate the Wnt signalling pathway, a critical pathway that is involved in cell cycle and cell differentiation, and is controlled by β-catenin. The data presented show that the expression of A49 ectopically or during VACV infection causes accumulation of β-catenin, and that A49 triggering of Wnt signalling is dependent on binding β-TrCP. This is consistent with A49 blocking the ability of β-TrCP to recognise β-catenin and IκBα, and possibly other cellular targets. Thus, A49 targetting of β-TrCP affects multiple cellular pathways, including the NF-κB and Wnt signalling cascades. PMID:29058646

  7. Modelo ARIMA para pronosticar valores de tráfico en una red de datos Wi-Fi

    Directory of Open Access Journals (Sweden)

    Cesar Augusto Hernández Suarez

    2009-05-01

    Full Text Available El presente artículo de investigación científica y tecnológica tiene por objetivo demostrar que las series de tiempo son una exce- lente herramienta para el modelamiento de tráfico de datos en redes Wi-Fi. Para lograr este objetivo se utilizó la metodología de Box-Jenkins, la cual se describe. El modelamiento de tráfico Wi-Fi a través de modelos correlacionados como las series de tiem- po, permiten ajustar gran parte de la dinámica del comportamiento de los datos en una ecuación y con base en esto estimar va- lores futuros de tráfico. Lo anterior es una ventaja para la planeación de cobertura, reservación de recursos y la realización de un control más oportuno y eficiente en forma integrada a diferentes niveles de la jerarquía funcional de la red de datos Wi-Fi. Como resultado de la investigación se obtuvo un modelo de tráfico ARIMA de orden 6, el cual realizó pronósticos de tráfico con valores del error cuadrático medio relativamente pequeños, para un periodo de 18 días.

  8. beta-TrCP inhibition reduces prostate cancer cell growth via upregulation of the aryl hydrocarbon receptor.

    Directory of Open Access Journals (Sweden)

    Udi Gluschnaider

    2010-02-01

    Full Text Available Prostate cancer is a common and heterogeneous disease, where androgen receptor (AR signaling plays a pivotal role in development and progression. The initial treatment for advanced prostate cancer is suppression of androgen signaling. Later on, essentially all patients develop an androgen independent stage which does not respond to anti hormonal treatment. Thus, alternative strategies targeting novel molecular mechanisms are required. beta-TrCP is an E3 ligase that targets various substrates essential for many aspects of tumorigenesis.Here we show that beta-TrCP depletion suppresses prostate cancer and identify a relevant growth control mechanism. shRNA targeted against beta-TrCP reduced prostate cancer cell growth and cooperated with androgen ablation in vitro and in vivo. We found that beta-TrCP inhibition leads to upregulation of the aryl hydrocarbon receptor (AhR mediating the therapeutic effect. This phenomenon could be ligand independent, as the AhR ligand 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD did not alter prostate cancer cell growth. We detected high AhR expression and activation in basal cells and atrophic epithelial cells of human cancer bearing prostates. AhR expression and activation is also significantly higher in tumor cells compared to benign glandular epithelium.Together these observations suggest that AhR activation may be a cancer counteracting mechanism in the prostate. We maintain that combining beta-TrCP inhibition with androgen ablation could benefit advanced prostate cancer patients.

  9. T-R CYCLE CHARACTERIZATION AND IMAGING: ADVANCED DIAGNOSTIC METHODOLOGY FOR PETROLEUM RESERVOIR AND TRAP DETECTION AND DELINEATION

    Energy Technology Data Exchange (ETDEWEB)

    Ernest A. Mancini

    2004-09-24

    The principal research effort for Year 1 of the project has been T-R cycle characterization and modeling. The research focus for the first nine (9) months of Year 1 was on outcrop study, well log analysis, seismic interpretation and data integration and for the remainder of the year the emphasis has been on T-R cycle model development. Information regarding the characteristics of T-R cycles has been assembled from the study of outcrops, from well log analyses, and from seismic reflection interpretation. From these studies, stratal boundaries separating T-R cycles have been found to be useful for the recognition and delineation of these cycles. The key stratal surfaces include subaerial unconformities, shoreface ravinement surfaces, transgressive surfaces, surfaces of maximum regression, and surfaces of maximum transgression. These surfaces can be identified and mapped in surface exposures and can be recognized in well log signatures and seismic reflection profiles as discontinuities. The findings from the study of outcrop, well log, and seismic reflection data are being integrated into a database for use in constructing a model for T-R cycle development.

  10. Assessment of documentation of DSM-IV-TR Criteria A for diagnosis of schizophrenia in psychiatric unit, tertiary hospital, Malaysia.

    Science.gov (United States)

    Maung, K; Ohnmar, H; Than, W; Ramli, M; Najwa Hanim, M R; Ali Sabri, R; Ahmad Zafri, A B

    The purposes of this study were to investigate the documentation of the DSM-IV-TR- Criteria A in diagnoses of schizophrenia and to identify the symptoms associated with over diagnosis of schizophrenia. This study involved a retrospective review and analysis of data from case notes. Data of 107 newly diagnosed patients with schizophrenia were keyed in and analyzed using SPSS v 19. The cases were then evaluated for the use of the DSM-IV-TR- Criteria A. Over diagnosis was noted in 37.39% of the patients. Disorganised behaviour (12.5%), affective flattening (12.5%), hallucination (16%) and non-bizarre delusion (18.3%) significantly contributed to the over-diagnosis of schizophrenia. Symptoms such as non-bizarre delusion and hallucination were the most commonly used in over-diagnosing schizophrenia and were statistically significant with p ≤0.05. There was a significant lack of DSM-IV-TR Criteria A among the data documented to diagnose schizophrenia and non-bizarre delusion and hallucination were the most commonly used in over-diagnosing schizophrenia. This key problem needs to be addressed. The reliability of a diagnosis is indispensable and achievable with the proper clinical application of DSM-IV-TR Criteria A. The DSM-IV-TR Criteria have been perceived to be useful and reliable and is most widely used throughout the world.

  11. Dostoiévski em três novelas de juventude

    Directory of Open Access Journals (Sweden)

    Renato M. Perissinotto

    2009-01-01

    Full Text Available Este artigo analisa três novelas de juventude escritas por Fiódor Dostoiévski: Pobre gente, O duplo e Coração frágil. O texto tem dois objetivos fundamentais: primeiro, recusar a tese de que o autor russo, proverbial analista da alma humana, teria se despreocupado com os condicionantes sociais da ação dos seus personagens; em segundo lugar, pretende-se defender que a sociedade se faz presente nesses escritos por meio de uma "intuição sociológica" que Dostoiévski opera quando analisa os baixos funcionários da Rússia do século XIX. O texto está dividido em três partes: na primeira, descrevo a estrutura estatal da sociedade russa no século XIX; na segunda, apresento a descrição das condições de vida dos personagens e, por fim, analiso a forma pela qual o autor russo apresenta as interações sociais em que eles estão inseridos.The article analyses three novels by Fiodor Dostoievski: Poor people, The double and A faint heart. The article has two purposes: firstly, it refuses the usual thesis according to which the Russian author, a proverbial analyst of human soul, would be unconcerned about the social constraints on the action of his personages; secondly, it defends that these social constraints are present in his writings as a "sociological intuition" operated by Dostoievski when he analyses the rank-and-file officials of the Russian bureaucracy in the XIXth century. The text is divided in three parts: the first one describes the state structure of Russian society in the XIXth century; the second part describes the life conditions of the personages and, at last, the third part analyzes the way the Russian author presents the social interaction in which they are inserted.

  12. TrOn: an anatomical ontology for the beetle Tribolium castaneum.

    Directory of Open Access Journals (Sweden)

    Jürgen Dönitz

    Full Text Available In a morphological ontology the expert's knowledge is represented in terms, which describe morphological structures and how these structures relate to each other. With the assistance of ontologies this expert knowledge is made processable by machines, through a formal and standardized representation of terms and their relations to each other. The red flour beetle Tribolium castaneum, a representative of the most species rich animal taxon on earth (the Coleoptera, is an emerging model organism for development, evolution, physiology, and pest control. In order to foster Tribolium research, we have initiated the Tribolium Ontology (TrOn, which describes the morphology of the red flour beetle. The content of this ontology comprises so far most external morphological structures as well as some internal ones. All modeled structures are consistently annotated for the developmental stages larva, pupa and adult. In TrOn all terms are grouped into three categories: Generic terms represent morphological structures, which are independent of a developmental stage. In contrast, downstream of such terms are concrete terms which stand for a dissectible structure of a beetle at a specific life stage. Finally, there are mixed terms describing structures that are only found at one developmental stage. These terms combine the characteristics of generic and concrete terms with features of both. These annotation principles take into account the changing morphology of the beetle during development and provide generic terms to be used in applications or for cross linking with other ontologies and data resources. We use the ontology for implementing an intuitive search function at the electronic iBeetle-Base, which stores morphological defects found in a genome wide RNA interference (RNAi screen. The ontology is available for download at http://ibeetle-base.uni-goettingen.de.

  13. TrOn: an anatomical ontology for the beetle Tribolium castaneum.

    Science.gov (United States)

    Dönitz, Jürgen; Grossmann, Daniela; Schild, Inga; Schmitt-Engel, Christian; Bradler, Sven; Prpic, Nikola-Michael; Bucher, Gregor

    2013-01-01

    In a morphological ontology the expert's knowledge is represented in terms, which describe morphological structures and how these structures relate to each other. With the assistance of ontologies this expert knowledge is made processable by machines, through a formal and standardized representation of terms and their relations to each other. The red flour beetle Tribolium castaneum, a representative of the most species rich animal taxon on earth (the Coleoptera), is an emerging model organism for development, evolution, physiology, and pest control. In order to foster Tribolium research, we have initiated the Tribolium Ontology (TrOn), which describes the morphology of the red flour beetle. The content of this ontology comprises so far most external morphological structures as well as some internal ones. All modeled structures are consistently annotated for the developmental stages larva, pupa and adult. In TrOn all terms are grouped into three categories: Generic terms represent morphological structures, which are independent of a developmental stage. In contrast, downstream of such terms are concrete terms which stand for a dissectible structure of a beetle at a specific life stage. Finally, there are mixed terms describing structures that are only found at one developmental stage. These terms combine the characteristics of generic and concrete terms with features of both. These annotation principles take into account the changing morphology of the beetle during development and provide generic terms to be used in applications or for cross linking with other ontologies and data resources. We use the ontology for implementing an intuitive search function at the electronic iBeetle-Base, which stores morphological defects found in a genome wide RNA interference (RNAi) screen. The ontology is available for download at http://ibeetle-base.uni-goettingen.de.

  14. O mapa íntimo: três telas de Frida Kahlo Frida Kahlo's intimate map

    Directory of Open Access Journals (Sweden)

    Fabiano Seixas Fernandes

    2008-04-01

    Full Text Available O artigo apresenta análises de três telas da pintora mexicana Frida Kahlo - Las dos Fridas, Autorretrato en la frontera entre México y Estados Unidos e Lo que el agua me dio - e está dividido em três partes, cada qual tratando de uma tela em particular, para, no momento seguinte, ligar seu estudo ao das demais. Norteia a leitura das primeiras a discussão da relação nacional/estrangeiro no trabalho de Kahlo; a análise da terceira mostra a superação da dicotomia através do conceito de mapa íntimo, no qual entra em cena uma tênue e instável territorialização da memória através da representação pictórica.This article analyses three works by Mexican painter Frida Kahlo: Las dos Fridas (The Two Fridas, Autorretrato en la frontera entre México y Estados Unidos (Self-Portrait on the Borderline between Mexico and the United States, and Lo que el agua me dio (What the Water Gave Me. Each work is first analyzed separately and then connected with the others. The analysis of the first two is guided by the national/foreign dichotomy present in Kahlo; the analysis of the third shows the overcoming of the dichotomy through the concept of intimate map - in which a feeble and ever-changing territorialization of memory via plastic expression comes to show.

  15. Why live recording sounds better: A case study of Schumann’s Träumerei

    Directory of Open Access Journals (Sweden)

    Haruka eShoda

    2015-01-01

    Full Text Available We explore the concept that artists perform best in front of an audience. The negative effects of performance anxiety are much better known than their related cousin on the other shoulder: the positive effects of social facilitation. The present study, however, reveals a listener's preference for performances recorded in front of an audience. In Study 1, we prepared two types of recordings of Träumerei performed by 13 pianists: recordings in front of an audience and those with no audience. According to the evaluation by 153 listeners, the recordings performed in front of an audience sounded better, suggesting that the presence of an audience enhanced or facilitated the performance. In Study 2, we analyzed pianists' durational and dynamic expressions. According to the functional principal components analyses, we found that the expression of Träumerei consisted of three components: the overall quantity, the cross-sectional contrast between the final and the remaining sections, and the control of the expressive variability. Pianists' expressions were targeted more to the average of the cross-sectional variation in the audience-present than in the audience-absent recordings. In Study 3, we explored a model that explained listeners' responses induced by pianists' acoustical expressions, using path analyses. The final model indicated that the cross-sectional variation of the duration and that of the dynamics determined listeners' evaluations of the quality and the emotionally moving experience, respectively. In line with human's preferences for commonality, the more average the durational expressions were in live recording, the better the listeners' evaluations were regardless of their musical experiences. Only the well-experienced listeners (at least 16 years of musical training were moved more by the deviated dynamic expressions in live recording, suggesting a link between the experienced listener's emotional experience and the unique dynamics in

  16. Potencial discriminatório de três testadores em "topcrosses" de milho

    Directory of Open Access Journals (Sweden)

    Duarte Iran de Azevedo

    2003-01-01

    Full Text Available O objetivo deste trabalho foi determinar o potencial de três testadores endogâmicos elites a fim de avaliar e classificar 15 materiais genéticos para a síntese de híbridos. Quarenta e cinco híbridos mais quatro testemunhas foram avaliados em cinco ambientes, no ano agrícola 2000/2001, utilizando delineamento em blocos ao acaso, com três repetições. Foram avaliados os caracteres peso de grãos corrigido, altura de planta e altura de espiga. As estimativas de capacidade geral e específica de combinação foram obtidas pelo modelo de Griffing, adaptado por Vencovsky e Barriga, para análise em delineamento genético fatorial. O rendimento médio obtido entre os cinco ambientes variou de 8,97 t ha-1 a 12,21 t ha-1. Vinte e sete tratamentos superaram a média geral absoluta da melhor testemunha. A análise de variância conjunta revelou efeitos significativos de ambientes, capacidade geral de combinação dos parentais e testadores, capacidade específica de combinação e das interações ambiente x capacidade geral de combinação dos parentais e testadores. Os testadores promoveram uma classificação diferenciada para a base genética avaliada, com destaque para os cruzamentos entre parentais HS1, HS2, HS5 e HT4 com o testador LF e parentais L10 e HS5 com o testador L05.

  17. Evolução dos acidentes de trânsito em um grande centro urbano, 1991-2000

    OpenAIRE

    Oliveira, Zenaide Calazans de; Mota, Eduardo Luiz Andrade; Costa, Maria da Conceição Nascimento

    2008-01-01

    p. 364-372, fev, 2008 Este estudo descreve a evolução dos acidentes de trânsito Salvador, Bahia, Brasil, entre 1991 e 2000, utilizando- se dados do Departamento Estadual de Trânsito do Estado da Bahia. Calculou-se taxas globais dos acidentes de trânsito, vítimas e taxas padronizadas de mortalidade por habitante e por veículos, e comparou-se médias destes indicadores para antes (1991 a 1994) e após (1995 a 2000) a adoção de medidas de intervenção como o uso do cinto de segurança e o Código ...

  18. [Forensic assessment of DSM-5 posttraumatic stress disorder: a commentary on the transition from DSM-IV-TR (I)].

    Science.gov (United States)

    Stevens, A; Fabra, M

    2013-12-01

    In May 2013 the American Psychiatric Association (APA) has released the latest and fifth edition of the diagnostic and statistical manual of mental disorders (DSM-5). Like its predecessor, the DSM-IV-TR, it will have considerable impact on the science of Psychiatry. The DSM-5 describes - actually available in English - the present medical knowledge about mental disorders. In the short run, German medical science and scientific medicolegal expertises will continue to rely on the German version of the DSM-IV-TR, however, they will be difficult to defend without bearing in mind the changes that DSM-5 brings about. This report discusses the transition from DSM-IV-TR to DSM-5 with regard to posttraumatic stress disorder (PTSD) and provides suggestions, how the criteria might be evaluated.

  19. A tríade “Verdadeiro-Bom-Belo”: O lugar da beleza na Idade Média

    Directory of Open Access Journals (Sweden)

    Jan A. Aertsen

    2008-06-01

    Full Text Available Neste artigo, Jan Aertsen discute a compreensão da tríade “Verdadeiro-Belo-Bom” como representante de um conjunto de questões clássicas em filosofia, a qual corresponderia, do ponto de vista moderno, à suposição de que o sujeito possui três modos distintos de se relacionar com o mundo: cognitivo, estético e prático. O autor sugere que a tríade foi formulada explicitamente pela primeira vez na Idade Média; neste período, entretanto, a beleza não era considerada um problema “estético”.

  20. Hebephilia is not a mental disorder in DSM-IV-TR and should not become one in DSM-5.

    Science.gov (United States)

    Frances, Allen; First, Michael B

    2011-01-01

    The paraphilia section of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) is being misinterpreted in the forensic evaluations of sexually violent offenders. The resulting misuse of the term paraphilia not otherwise specified, hebephilia, has justified the inappropriate involuntary commitment of individuals who do not in fact qualify for a DSM-IV-TR diagnosis of mental disorder. This article has two purposes: to clarify what the DSM-IV-TR was meant to convey and how it has been twisted in translation within the legal system, and to warn that the DSM-5 proposal to include pedohebephilia threatens to make the current bad situation very much worse in the future.

  1. Mielotomia punctiforme no tratamento da dor oncológica visceral: análise de três casos

    OpenAIRE

    Francisco,Alexandre N.; Lobão,Carlos A.F.; Sassaki,Viviane S.; Garbossa,Maria C.P.; Aguiar,Luiz R.

    2006-01-01

    INTRODUÇÃO: Uma nova via relacionada com a dor visceral foi recentemente descrita. Esta via localiza-se na linha média da coluna dorsal na medula espinhal, sendo o alvo da técnica cirúrgica aqui descrita. OBJETIVO: Apresentar os resultados de três pacientes submetidos ao tratamento da dor visceral oncológica por mielotomia punctiforme. MÉTODO: Três pacientes, com dor abdominal oncológica refratária ao tratamento clínico, foram submetidos à mielotomia punctiforme por meio de de pequena laminec...

  2. Influencia del flujo de tráfico vehicular en la contaminación sonora del Cercado de Lima

    OpenAIRE

    Visaga Fernández, Sandra Indira; E. P. de Ingeniería Ambiental, Universidad Peruana Unión - Lima

    2016-01-01

    En este trabajo, se ha realizado una medición experimental de los niveles de ruido en 61 puntos estratégicos previamente definidos mediante una evaluación de la distribución espacial del Cercado de Lima, y a la vez en estosmismos puntos se ha recolectado información sobre el flujo del tráfico vehicular para determinar su influencia en la contaminación sonora. Para la recolección de data de campo; niveles de ruido y flujo de tráfico vehicular, se hadeterminado una distribución temporal, compre...

  3. T-R Cycle Characterization and Imaging: Advanced Diagnostic Methodology for Petroleum Reservoir and Trap Detection and Delineation

    Energy Technology Data Exchange (ETDEWEB)

    Ernest A. Mancini

    2006-08-30

    Characterization of stratigraphic sequences (T-R cycles or sequences) included outcrop studies, well log analysis and seismic reflection interpretation. These studies were performed by researchers at the University of Alabama, Wichita State University and McGill University. The outcrop, well log and seismic characterization studies were used to develop a depositional sequence model, a T-R cycle (sequence) model, and a sequence stratigraphy predictive model. The sequence stratigraphy predictive model developed in this study is based primarily on the modified T-R cycle (sequence) model. The T-R cycle (sequence) model using transgressive and regressive systems tracts and aggrading, backstepping, and infilling intervals or sections was found to be the most appropriate sequence stratigraphy model for the strata in the onshore interior salt basins of the Gulf of Mexico to improve petroleum stratigraphic trap and specific reservoir facies imaging, detection and delineation. The known petroleum reservoirs of the Mississippi Interior and North Louisiana Salt Basins were classified using T-R cycle (sequence) terminology. The transgressive backstepping reservoirs have been the most productive of oil, and the transgressive backstepping and regressive infilling reservoirs have been the most productive of gas. Exploration strategies were formulated using the sequence stratigraphy predictive model and the classification of the known petroleum reservoirs utilizing T-R cycle (sequence) terminology. The well log signatures and seismic reflector patterns were determined to be distinctive for the aggrading, backstepping and infilling sections of the T-R cycle (sequence) and as such, well log and seismic data are useful for recognizing and defining potential reservoir facies. The use of the sequence stratigraphy predictive model, in combination with the knowledge of how the distinctive characteristics of the T-R system tracts and their subdivisions are expressed in well log patterns

  4. Psicópatas integrados en las relaciones de pareja: la tríada oscura de la personalidad

    OpenAIRE

    Pozueco Romero, José Manuel

    2016-01-01

    Tres son los principales perfiles de personalidad que se ha constatado influyen muy negativamente en cualquier tipo de relación íntima, ya sea ésta de corta o larga duración: la psicopatía, el maquiavelismo y el narcisismo. Al grupo de estos tres tipos de personalidades se les conoce como la tríada oscura de la personalidad. Diversos estudios han investigado las relaciones entre esta tríada oscura de la personalidad y las relaciones amorosas, evidenciando que emplean diversas tácticas de c...

  5. Sør-Trøndelag Aktivitets-Relaterte Tiltak (START – Samhandling for bedre helse

    Directory of Open Access Journals (Sweden)

    Tommy Aune Rehn

    2011-08-01

    Full Text Available Høy forekomst av kroniske sykdommer og stigende helseutgifter representerer i lys av den kommende eldrebølgenen stor samfunnsøkonomisk utfordring. Den negative helseutviklingen er i ferd med å bli et nasjonalt problem og må få konsekvenser for fremtidig norsk helsepolitikk. Fysisk inaktivitet er en livsstilsfaktor som er sterkt assosiert med lavt nivå av kondisjon, total dødelighet og død av hjerte- og karsykdom. Studier viser at selv en liten bedring i kondisjon forventes å gi betydelig økt forventet levealder og at individer som har et bra kondisjonsnivå har opptil 15 flere leveår med god helse hvor de er selvhjulpne. Økt fysisk aktivitet har en gunstig effekt på alle risikofaktorer for kronisk sykdom og tidlig død, og vi mener derfor at man bør legge til rette for å øke det generelle fysiske aktivitetsnivået i befolkningen og bedre kunnskapen om fysisk aktivitet. Økt fysisk aktivitet vil forventes å bedre folkehelsen ved å redusere sykdomsforekomst, medisinbruk og dødelighet samt øke arbeidsevnen i populasjonen, noe som igjen vil redusere de samfunnsøkonomiske utgiftene. For å lykkes med dette, har vi tatt initiativ til prosjektet ”Sør-Trøndelag Aktivitets-Relaterte Tiltak” (START, som er tenkt å være en koordinert populasjonsbasert samhandling for bedre helse gjennom økt fysisk aktivitet rettet mot alle lag i befolkningen, fra krybbe til grav. Målet er at START skal danne grunnlag for nasjonal implementering av tiltak slik at vi oppnår en helsepolitisk bærekraftig utvikling i årene som kommer. Denne artikkelenbeskriver START og bakgrunnen for prosjektet.Rehn TA, Rognmo Ø, Ingebrigtsen JE, Vik JT, Wisløff U. Sør-Trøndelag Activity-Related Trial (START –Cooperation for better health. Nor J Epidemiol 2011; 20 (2: 209-216.ENGLISH SUMMARYHigh incidence of chronic diseases and rising health expenditure represents in light of the increasing proportion of elderly in our society a development that cannot

  6. Compressibilidade de três Latossolos em função da umidade e uso

    Directory of Open Access Journals (Sweden)

    M. K. Kondo

    1999-06-01

    Full Text Available Por meio do ensaio de compressibilidade, foram estudados os efeitos do manejo e da umidade na pressão de preconsolidação (σp de três solos: Latossolo Vermelho-Amarelo, Latossolo Roxo e Latossolo Vermelho-Escuro sob cultura anual, mata natural e pastagem, na região de Lavras (MG, em duas profundidades (0-0,03 e 0,27-0,30 m. Para cada condição, foram coletadas cinco amostras indeformadas e uma deformada, com três repetições. As amostras, indeformadas e com diferentes umidades, foram utilizadas no ensaio de compressão uniaxial, obtendo-se as curvas de compressão, das quais foram extraídas as respectivas pressões de preconsolidação. Com as amostras deformadas, determinaram-se os limites de plasticidade e de contração, textura e matéria orgânica. Os modelos de compactação testados foram baseados na pressão de preconsolidação e na umidade do solo. Para uma mesma condição e profundidade, houve diferença significativa entre os valores dos teores de argila e areia nos três solos. Os valores da densidade do solo inicial (Ds i foram estatisticamente diferentes para todas as condições na mesma profundidade, exceto na camada de 0-0,03 m para a cultura anual. À medida que a umidade do solo aumentou, a pressão de preconsolidação decresceu exponencialmente, indicando uma redução na capacidade de suporte de carga do solo. O LR apresentou, em geral, maior capacidade de suporte de carga do que o LE e LV. Essa maior capacidade de suporte de carga pode estar associada com o seu maior teor de argila e menor teor de areia. A capacidade de suporte de carga na zona de friabilidade variou de 154 a 167 kPa, para o LV; de 77 a 183 kPa, para o LR, e de 77 a 132 kPa, para o LE. As umidades 0,33 a 0,30 kg kg-1, 0,42 a 0,27 kg kg-1, e 0,35 a 0,33 kg kg-1 correspondem à faixa de friabilidade (LP - LC do LV, LR e LE, respectivamente. O modelo baseado na história de tensão do solo evidenciou o efeito da compactação causada pelas m

  7. Distribuidor de tránsito «La Araña» (Venezuela

    Directory of Open Access Journals (Sweden)

    Editorial, Equipo

    1965-12-01

    Full Text Available The location of Caracas city, the road system that converges on it, and the rapid growth of the town in a particular direction due to the special topography of the neighborhood, have led to very considerable traffic difficulties. To guide this traffic correctly it has been necessary to build a traffic distributor; called «the spider», at which traffic crosses at four different levels. Obviously, serious technical problems have had to be faced to overcome the low strength of the soil, and its difficult contours. Owing to the large size and extension of the project, the precasting of many special units has been a most important factor. The girders and structural columns are of prestressed concrete, and the foundations, which rest on a variety of piles, are of reinforced concrete. The project has been financed by the Ministry of Public Works, and is now in an advanced state of completion, but the final stage is yet to be done. The total budget for this project is about 600 m. pesetas. The present article describes the total work and gives some brief details on the methods of calculation and execution that were adopted.La situación de Caracas y el sistema vial que concurre en su casco urbano, junto con la expansión de la ciudad en una dirección determinada, provocada por condiciones topográficas locales, han creado un problema de encauzamiento del tránsito que culmina en la necesidad de construir un distribuidor de tráfico, denominado «La Araña», en el que se cruzan las calzadas a cuatro niveles distintos. Como es lógico, se han tenido que afrontar serios problemas técnicos para vencer accidentes locales y terrenos de apoyo de pobre capacidad de sustentación. Dado el gran volumen, variedad y dispersión de obras, la prefabricación de elementos básicos ha sido imperiosa. Las vigas y entramados estructurales son de hormigón pretensado, y los cimientos, con bases apoyadas sobre pilotes de distintos tipos, de hormigón armado ordinario

  8. Estudo da atividade do látex do Croton urucurana Baill. sobre o trânsito gastrintestinal de camundongos

    OpenAIRE

    Gurgel, Luilma Albuquerque; Martins, Domingos Tabajara de Oliveira; Mattos, Paulo Orlandi; Rao, Vietla Satyanarayana

    2002-01-01

    O presente trabalho tem como propósito avaliar uma possível atividade inibitória do látex do Croton urucurana Baill. sobre o trânsito gastrintestinal de camundongos, bem como tentar esclarecer os possíveis mecanismos de ação envolvidos em sua atividade. Foram utilizados os modelos de trânsito gastrintestinal normal e trânsito gastrintestinal estimulado por fisostigmina em camundongos. Os resultados obtidos mostram que o látex inibiu o trânsito gastrintestinal de camundongos, e, muito embora s...

  9. La tríada oscura de la personalidad: maquiavelismo, narcisismo y psicopatía. Una mirada evolutiva

    Directory of Open Access Journals (Sweden)

    Fernando Renee González Moraga

    2015-08-01

    Full Text Available Se aborda la denominada Tríada Oscura de la Personalidad -Tríada- (maquiavelismo, narcisismo subclínico y psicopatía subclínica desde una mirada evolutiva. El objetivo de esta investigación es revisar la evidencia que han presentado los teóricos evolucionistas sobre la Tríada, desde un acercamiento a la mirada evolutiva. Para esto, se indaga en las principales características de cada uno de estos rasgos, los instrumentos que se han utilizado para evaluarlos y las principales áreas en donde se han estudiado. La mirada evolutiva plantea que los rasgos de la Tríada son dimensionales y varían de acuerdo con las diversas estrategias que utilizan los sujetos para adaptarse a las características socioambientales en las que se desarrollan. Estos rasgos se caracterizan por presentar violencia psicológica, inhibición moral, manipulación, baja amabilidad, insensibilidad, egoísmo y dificultad para mentalizar en contextos de interacción interpersonal y social.

  10. TR{alpha}- and TSH-mRNA levels after temporal exposition with methimazole in zebrafish, Danio rerio

    Energy Technology Data Exchange (ETDEWEB)

    Schulz, A.E.I.; Stocker, A.; Hollosi, L.; Schramm, K.W. [Inst. of Ecological Chemistry, GSF - National Research Center for Environment and Health (Germany)

    2004-09-15

    The group of dioxin and dioxin-like substances are highly persistent in the environment. There are evidences from present investigations that a variety of substances are capable of disrupting the endocrine system in the aquatic environment. These substances are called endocrine disruptors. Dioxin and related compounds can act as endocrine disruptors. Aquatic animals like amphibian and fish are especially affected of the impact of these compounds. Investigations concerned so far in particular the domain of reproduction biology and the thyroid axis especially. Recent investigations showed that the TR{alpha}-mRNA level change after a short temporal expression with T3, methimazole and amiodarone. The objective of the project is to identify effects of thyroid endocrine disruptors on the regulation of gene expression of the thyroid receptors TR{alpha}a, TR{beta} and thyroid stimulating hormone TSH and associated effects on other system. In preliminary studies the effects of the drug methimazole as model substance on gene expression of TR{alpha} and TSH were investigated. Methimazole is an inhibitor of the thyroid peroxidase so that the formation of thyroid hormones is disrupted.

  11. Variability among Research Diagnostic Interview Instruments in the Application of "DSM-IV-TR" Criteria for Pediatric Bipolar Disorder

    Science.gov (United States)

    Galanter, Cathryn A.; Hundt, Stephanie R.; Goyal, Parag; Le, Jenna; Fisher, Prudence W.

    2012-01-01

    Objective: The "DSM-IV-TR "criteria for a manic episode and bipolar disorder (BD) were developed for adults but are used for children. The manner in which clinicians and researchers interpret these criteria may have contributed to the increase in BD diagnoses given to youth. Research interviews are designed to improve diagnostic reliability and…

  12. Dimensión social del tráfico ilícito de bienes culturales

    OpenAIRE

    García, Tania

    2012-01-01

    Cadena de involucrados en el TIBC. Huaqueros y coleccionistas. Régimen de tenencia de tierra y sitios arqueológicos. Colecciones arqueológicas registradas por el INPC. Blanqueo de bienes. Seguridad ciudadana y tráfico ilícito de bienes culturales. Universidad Tecnológica de El Salvador

  13. Transporter mRNA expression in a conditionally immortalized rat small intestine epithelial cell line (TR-SIE).

    Science.gov (United States)

    Hosoya, Ken-ichi; Tomi, Masatoshi; Takayama, Megumi; Komokata, Yuko; Nakai, Daisuke; Tokui, Taro; Nishimura, Kenji; Ueda, Masatsugu; Obinata, Masuo; Hori, Satoko; Ohtsuki, Sumio; Amidon, Gordon L; Terasaki, Tetsuya

    2004-08-01

    Small intestine epithelial cell lines (TR-SIE), which are established from the small intestine of transgenic rats harboring temperature-sensitive simian virus 40 large T-antigen gene (tsA58 Tg rat), were used to characterize the mRNA expression of small intestine transporters. TR-SIE cells had a polygonal morphology and expressed cytokeratin protein and villin mRNA. Although the large T-antigen was strongly expressed at 33 degrees C, this was reduced at 37 and 39 degrees C. Concomitantly, the cell growth was arrested at 37 and 39 degrees C compared with that at 33 degrees C, suggesting that TR-SIE cells are conditionally immortalized cell lines. RT-PCR analysis revealed that TR-SIE cells expressed ABCB1 (mdr1a and mdr1b), ABCB4 (mdr2), ABCC2 (mrp2), ABCC6 (mrp6), ABCG1, ABCG2 (bcrp/mxr), Slc21a7 (Oatp3), Slc15a1 (PepT1), and Slc16a1 (Mct1). Conditionally immortalized rat small intestine epithelial cell lines were established from tsA58 Tg rats and expressed the mRNA of intestinal transporters.

  14. Perfiles resilientes y calidad de vida en personas con discapacidad sobrevenida por accidentes de tráfico

    Directory of Open Access Journals (Sweden)

    Raquel Suriá Martínez

    2015-09-01

    Conclusión: Esto sugiere la necesidad de profundizar en el conocimiento de la resiliencia y en el diseño de programas que incrementen la calidad de vida de las personas con discapacidad tras un accidente de tráfico.

  15. A atualidade dos acidentes de trânsito na era da velocidade: uma visão geral

    Directory of Open Access Journals (Sweden)

    Marín Letícia

    2000-01-01

    Full Text Available Este artigo focaliza, numa perspectiva interdisciplinar, os estudos sobre acidentes de trânsito em escala nacional e internacional. Ele começa analisando o aumento da produção e consumo de veículos motorizados em todo o mundo e as transformações sociais que esse fato acarretou. Atenção especial é dada à degradação do meio ambiente urbano e ao enorme custo social representado pelos acidentes de trânsito. Em seguida, é apresentado um panorama epidemiológico sobre as vítimas do trânsito. A relação entre personalidade e acidente de trânsito mereceu atenção especial, principalmente no que se refere ao comportamento infrator e ao consumo de bebidas alcoólicas e de outras drogas. O artigo conclui enfatizando a necessidade de o Estado implementar políticas públicas específicas consistentes, a fim de se poder controlar o problema.

  16. Investigation of aeroacoustics and flow dynamics of a NACA 0015 airfoil with a Gurney flap using TR-PIV

    NARCIS (Netherlands)

    Shah, J.; Sciacchitano, A.; Pröbsting, S.

    The present study employs simultaneous planar TR-PIV and microphone measurements to obtain the flow dynamics and aeroacoustic causality correlation associated with a Gurney flap of various sizes in case of low Mach and high Reynolds number flows. The objectives are to investigate the secondary

  17. Kliniske retningslinjer for træning af aerob kapacitet og muskelstyrke til patienter med reumatoid artrit

    DEFF Research Database (Denmark)

    Larsen, Birgit Tine; Læssøe, Uffe; Kjær, Thomas

    Baggrund: Patienter med reumatoid artrit har en forhøjet risiko for udviklingen af cardio-vaskulære lidelser (CVD) ogtidlig død. Inflammation, smerter og generel træthed resulterer i nedsat muskelstyrke og lavt fysiskfunktions- og aktivitetsniveau hos mange af disse patienter, hvilket yderligere...... forstærker denne risiko. Formål: Gennem effektiv og sikker træning at øge RA patienters aerob kapacitet og muskel styrke for dermed atlette patienternes daglige aktiviteter. Patienter: Voksne patienter (> 18 år) med diagnosen reumatoid artrit ifølge ARA eller ACR/EULAR kriterierne,funktionsklasserne I, II og...... reumatoid artrit. Kortvarig landbaseret højintensitets træning af aerob kapacitet og muskelstyrke bør overvejes itræningen af patienter med reumatoid artrit. Længerevarende landbaseret højintensitets træning af aerob kapacitet og muskelstyrke bør overvejes itræningen af patienter med reumatoid artrit...

  18. Management of Fusarium oxysporum f.sp cubense (Foc-TR4) from banana by anaerobic soil disinfestation (ASD)

    NARCIS (Netherlands)

    Runia, W.T.

    2014-01-01

    Applied Plant Research in Lelystad has, commissioned by Gert Kema, Plant Research International (PRI) and leader of the Panama Project, performed a trial to measure the efficacy of anaerobic soil disinfestation (ASD) with a ‘Herbie” product against Fusarium oxysporum f.sp. cubense (Foc; TR 4),

  19. Dor-desprazer-trabalho docente: como desfazer essa tríade

    Directory of Open Access Journals (Sweden)

    Maria Elizabeth Barros de Barros

    2007-12-01

    Full Text Available O artigo apresenta a experiência do Programa de Formação e Investigação Sobre a Saúde e o Trabalho (PFST de docentes de escolas públicas, desenvolvido na Universidade Federal do Espírito Santo. Trata da problemática da saúde do conjunto de docentes que trabalham nas escolas públicas do município da Serra/ES, visando a desfazer a tríade dor-desprazer-trabalho docente, vivida de forma naturalizada pelo coletivo de docentes. Pretende avançar na compreensão das relações saúde-trabalho nas escolas e investigar as estratégias utilizadas por esses professores para resistirem às tentativas de desqualificação do trabalho docente. Afirma a possibilidade de se abrirem espaços de discussão no cotidiano dos docentes para que a luta pela saúde se constitua em redes de cooperação entre sujeitos e escolas, inaugurando-se outras formas de atuação desses estabelecimentos. Com esse objetivo, propõe uma metodologia de trabalho que tem se pautado na abordagem ergológica, construída na Universidade de Provença, em AIX/ França.

  20. Focusing and bunching of ion beam in axial injection channel of IPHC cyclotron TR24

    Science.gov (United States)

    Adam, T.; Ivanenko, I.; Kazarinov, N.; Osswald, F.; Traykov, E.

    2017-07-01

    The CYRCe cyclotron (CYclotron pour la ReCherche et l’Enseignement) is used at IPHC (Institut Pluridisciplinaire Hubert Curien) for the production of radio-isotopes for diagnostics, medical treatments and fundamental research in radiobiology. The TR24 cyclotron produced and commercialized by ACSI (Canada) delivers a 16-25 MeV proton beam with intensity from few nA up to 500 μA. The solenoidal focusing instead of existing quadrupole one is proposed in this report. The changing of the focusing elements will give the better beam matching with the acceptance of the spiral inflector of the cyclotron. The parameters of the focusing solenoid are found. Additionally, the main parameters of the bunching system are evaluated in the presence of the beam space charge. This system consists of the buncher installed in the axial injection beam line of the cyclotron. The using of the grid-less multi harmonic buncher may increase the accelerated beam current and will give the opportunity to new proton beam applications.

  1. La experiencia del embarazo en el tránsito de la adolescencia

    Directory of Open Access Journals (Sweden)

    Alicia Genolet

    2004-01-01

    Full Text Available El presente artículo expone el comportamiento estadístico de las madres adolescentes atendidas en su parto en el Servicio de Maternidad del Hospital «San Roque» (Paraná, Entre Ríos durante 1997, 1998 y 1999, y las vivencias y representaciones que portan un grupo de adolescentes (madres y no madres con relación a la maternidad y la anticoconcepción. El estudio estadístico se basó en una muestra de 890 fichas de parto, que fueron procesadas con el software SPSS. Por otra parte, la interpretación de los datos cualitativos permite construir las siguientes conceptualizaciones: Las adolescentes estudiadas sufren condiciones que hablan de una triple vulnerabilidad: por ser mujeres, por ser pobres y por ser adolescentes. La adolescencia constituye un momento de vulnerabilidad de los sujetos en su tránsito a la adultez, que cobra una significación especial cuando tiene lugar en situaciones de riesgo, fragilidad y precariedad en los vínculos relacionales, familiares y sociales. Las condiciones de vulnerabilidad y pobreza refuerzan la condición subordinada del género femenino: ejercicio de roles tradicionales (crianza de los hijos, trabajo doméstico, exclusión de instancias de participación social y educativas.

  2. Del tráfico entre antropología y arte contemporáneo

    Directory of Open Access Journals (Sweden)

    Xavier Andrade

    2007-06-01

    Full Text Available Tomando los estudios sobre la economía de las drogas ilícitas como referente metodológico, el artículo discute preliminarmente la noción de “tráfico” en relación a cuatro aspectos del cruce de fronteras entre la antropología y el arte contemporáneo. 1. Transportar o movilizar bienes –en este caso, simbólicos, esto es básicamente ideas, categorías y conceptos pero también estrategias de apropiación y recontextualización pertinentes tanto a la etnografía como al arte contemporáneo. 2. Describir el carácter “contaminante” que tales bienes eventualmente adquieren cuando circulan en diferentes contextos (académico, gestión cultural, artes visuales, provocando por ello estrategias defensivas entre unos y otros. 3. Dar cuenta del carácter conflictivo de las micro-prácticas que se ponen a prueba durante el diálogo entre distintos saberes sancionados académicamente como campos o disciplinas. 4. Discutir los códigos de la ilegalidad que acompañan a la calidad de “traficante” y el capital simbólico que se deriva de ello.

  3. Mise-en-film da fotografia em três documentários brasileiros

    Directory of Open Access Journals (Sweden)

    Glaura Cardoso Vale

    2016-08-01

    Full Text Available Este artigo busca analisar, em três filmes da cinematografia brasileira recente, os modos como a fotografia, entendida como dispositivo de rememoração, é colocada em cena, compreendendo-a como rastro da presença de algo que já se tornou ausente. Pretende-se discutir como, ao solicitar imagens retiradas dos "álbuns de família", corrobora-se a construção de narrativas que dão a ver a biografia de homens e mulheres comuns, reais ou imaginados pelo documentário. Verificar, em metodologias distintas, o exercício político e estético do fazer cinematográfico que expõe as fragilidades e possíveis frustrações na reconstrução de algo longínquo (do ponto de vista do personagem e desconhecido (do ponto de vista dos autores, por mais presente materialmente que esteja a imagem no ato da rememoração.

  4. Extension of ISA TR84.00.02 PFD equations to KooN architectures

    International Nuclear Information System (INIS)

    Oliveira, Luiz Fernando; Abramovitch, Rafael Nelson

    2010-01-01

    Simplified equations for PFD evaluation of the most used architectures are given in ISA TR84.00.02-2002 document. This paper introduces a generalization of those equations for applications to any KooN architecture. The meaning of each individual term in the derived equations is explained. To strengthen their validity, several comparisons are made between their results and those of a numerical integration model for PFD assessment. The results show that the values obtained with the generalized equations are very close to those of the numerical model, even for highly redundant configurations. Comparisons are also made with the analytical equations given in IEC 61508. It is argued that the ISA equations are conceptually more consistent than those of IEC 61508 even though the numerical differences between the results are not significant in most practical cases. Overall, the results indicate that the generalized KooN PFD equations derived here may be applied to systems with higher redundancy, thus partly contradicting suggestions made in the above ISA reference that such equations should only be used for the simplest configurations. Some specific practical situations to which they cannot be applied are also pointed out.

  5. Envolvimento paterno aos três meses de vida do bebê

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    Cesar Augusto Piccinini

    Full Text Available O presente estudo investigou o envolvimento paterno aos três meses de vida do bebê. Foram entrevistados 38 pais primíparos, com idades entre 20 e 40 anos. Realizou-se uma análise de conteúdo baseada nas dimensões do conceito de envolvimento paterno: interação, acessibilidade e responsabilidade. Os pais revelaram envolverem-se nas atividades de cuidado, embora nem sempre de maneira rotineira. Também relataram preocupações e envolvimento nas decisões relativas aos cuidados, educação e saúde do bebê. Contudo, consideravam que sua participação estava aquém da ideal em função das restrições impostas pelo trabalho. Os resultados apontam para um aumento no envolvimento paterno nos primeiros meses do bebê e para a necessidade de apoio aos pais neste momento de transição familiar.

  6. As de basura. El tráfico ilegal de residuos

    Directory of Open Access Journals (Sweden)

    Ulderico Pesce

    2016-01-01

    Full Text Available Ulderico Pesce (Rivello, 1963, uno de los más significativos autores-narradores del teatro de narración de marcado contenido civil, vuelve a tratar en Asso di Monnezza el inmenso problema del lucrativo reciclaje de deshechos, sobre todo industriales, en la Italia actual. No es esta la primera vez que trata el tema, aunque en esta ocasión, partiendo de la visión directa del joven Nicola, se centra en la sangrante connivencia entre mafia, entidades públicas y los bajos fondos metropolitanos. En esta línea de denuncia social se mueven, de hecho, todos sus espectáculos de narración  en la línea del llamado teatro civile, como Storie di scorie. Il pericolo nucleare in Italia, sobre el peligro nuclear en tierras italianas; FIATo sul collo, sobre los 21 días de lucha de los trabajadores de la Fiat en Melfi; L'innaffiatore del cervello di Passannante: L'anarchico che cercò di uccidere Umberto I di Savoia, sobre la trágica figura histórica de Passannante, quien intentó asesinar al rey Umberto I en 1878; o Il Triangolo degli schiavi: I lavoratori clandestini in Italia, un áspero montaje sobre las pésimas condiciones laborales de algunos inmigrantes en tierras italianas, como muy bien indica el título.

  7. Três mulheres no nazismo: Reflexões sobre as fontes do comportamento moral

    Directory of Open Access Journals (Sweden)

    Maria Claudia Coelho

    2009-07-01

    Full Text Available Este trabalho discute as fontes do comportamento moral. Seu ponto de partida é a crítica feita à sociologia da moral durkheimiana por Zygmunt Bauman, que problematiza os pressupostos da origem social da moral e sua natureza coercitiva. Bauman contrapropõe, com base nas obras de Hannah Arendt e Emmanuel Lévinas, uma concepção de moralidade cujo núcleo é a responsabilidade para com o outro. A discussão é empreendida com base em três filmes que retratam cada qual a trajetória de uma mulher durante o nazismo: Traudl Junge, Sophie Scholl e Leni Riefenstahl. O eixo da análise é o modo como responsabilidade, culpa e consciência se entrelaçam em suas trajetórias. This article discusses the sources of moral behaviour. Its point of departure is Zygmunt Bauman’s criticism of the Durkheimian sociology of morality, challenging the assumptions of the social origin of morality and its coercive nature. Drawing on Hannah Arendt’s and Emmanuel Levinas’ works, Bauman counter-proposes a concept of morality based on responsibility toward each other. The discussion is then developed in relation to three fi lms that portray, each in their own way, the experience of a woman during the Nazi regime: Traudl Junge, Sophie Scholl and Leni Riefenstahl. The analysis is centred on how responsibility, guilt and conscience intertwine in the course of those lives.

  8. The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003.

    Science.gov (United States)

    Boeckmann, Brigitte; Bairoch, Amos; Apweiler, Rolf; Blatter, Marie-Claude; Estreicher, Anne; Gasteiger, Elisabeth; Martin, Maria J; Michoud, Karine; O'Donovan, Claire; Phan, Isabelle; Pilbout, Sandrine; Schneider, Michel

    2003-01-01

    The SWISS-PROT protein knowledgebase (http://www.expasy.org/sprot/ and http://www.ebi.ac.uk/swissprot/) connects amino acid sequences with the current knowledge in the Life Sciences. Each protein entry provides an interdisciplinary overview of relevant information by bringing together experimental results, computed features and sometimes even contradictory conclusions. Detailed expertise that goes beyond the scope of SWISS-PROT is made available via direct links to specialised databases. SWISS-PROT provides annotated entries for all species, but concentrates on the annotation of entries from human (the HPI project) and other model organisms to ensure the presence of high quality annotation for representative members of all protein families. Part of the annotation can be transferred to other family members, as is already done for microbes by the High-quality Automated and Manual Annotation of microbial Proteomes (HAMAP) project. Protein families and groups of proteins are regularly reviewed to keep up with current scientific findings. Complementarily, TrEMBL strives to comprise all protein sequences that are not yet represented in SWISS-PROT, by incorporating a perpetually increasing level of mostly automated annotation. Researchers are welcome to contribute their knowledge to the scientific community by submitting relevant findings to SWISS-PROT at swiss-prot@expasy.org.

  9. A cobertura de ciência em três jornais paraenses: um estudo longitudinal

    Directory of Open Access Journals (Sweden)

    Vanessa Brasil de Carvalho

    Full Text Available Resumo Neste artigo, apresentamos uma proposta metodológica visando realizar um estudo longitudinal que fornecesse um panorama da cobertura de ciência em 130 anos, por três jornais importantes do Estado do Pará: A Província do Pará (1876-2002, Folha do Norte (1896-1974 e O Liberal (1946-atual. Analisamos um período de dois meses a cada dez anos, de 1876 a 2006, em cada jornal selecionado, de maneira que obtivemos um olhar em longo prazo que perpassou pela história dos periódicos e, portanto, por grande parte da história da imprensa no Pará e na Amazônia. Utilizamos análise de conteúdo e análise de frames da Mídia. Nossos dados mostram que houve ênfase na pesquisa em saúde, destaque para a ciência nacional e preocupação em contextualizar os fatos científicos. Controvérsias e incertezas científicas ganharam pouco espaço nos jornais analisados.

  10. Field and city: Grande Sertão and Tristes Trópicos

    Directory of Open Access Journals (Sweden)

    Abel da Silveira Viana

    2008-07-01

    Full Text Available Until what point the intellectual improvement made possible the improvement in the social relations between field and city in Brazil of 20th century middle? The articulated and displayed images by important intellectuals were many times entailed to a supposed necessity of governmental public politics directed to the field inhabitant. The constatation takes us to at least two questions: the disguise of a superficial human being construction, which is, the idea of democratic State, based in a false politics unit, social and cultural, when not racial; and, as a consequence, the subjugation of social groups kept out of society, which the field inhabitant is one example. For the evaluation of this problem, we have two basic texts, for joining a important dimension to think about the problem of the representation and state homogenization: for being central in the debate on the relation field-city, and to establish dialogue with the academic thought of its time. These workmanships, which the article talks about, are Tristes trópicos, by Claude Lévi-Strauss, and Grande sertão: veredas by João Guimarães Rosa.

  11. In vitro activity of tedizolid (TR-700) against linezolid-resistant staphylococci.

    Science.gov (United States)

    Rodríguez-Avial, Iciar; Culebras, Esther; Betriu, Carmen; Morales, Gracia; Pena, Irene; Picazo, Juan J

    2012-01-01

    To compare the activity of tedizolid (formally known as torezolid and TR-700) with that of 15 agents against a collection of linezolid-resistant staphylococci (164 coagulase-negative staphylococci and 5 Staphylococcus aureus). Antimicrobial susceptibility tests were performed using the broth microdilution method following the recommendations of the CLSI. All isolates were susceptible to vancomycin and tigecycline. Based on the MIC(90) values, the potency of tedizolid against coagulase-negative staphylococci was >16-fold greater than that of linezolid. Tedizolid retained activity against most of the linezolid-resistant staphylococci tested, including multidrug-resistant isolates with elevated linezolid MICs (32 to >128 mg/L). Of the isolates, 79.2% and 31.4% were inhibited by tedizolid at ≤ 4 mg/L and ≤ 2 mg/L, respectively. The results of this study confirm the activity of tedizolid against linezolid-resistant staphylococci. This new oxazolidinone could have an important role as a potential therapeutic agent against multidrug-resistant staphylococci.

  12. Um mundo metafísico nos trópicos

    Directory of Open Access Journals (Sweden)

    Else Ribeiro Pires Vieira

    2008-04-01

    Full Text Available A fonte torna-se a estrela inatingível e pura que, sem se deixar contaminar, contamina, brilha para os artistas dos países da América Latina... ilumina os movimentos das mãos, mas ao mesmo tempo torna os artistas súditos do seu magnetismo superior.. Silviano Santiago, Uma literatura nos trópicos Afastando-me do discurso crítico em torno das influências e do caráter tributário a ele inerente, sobre o qual nos adverte Santiago já em ensaio de 1971,1 afastando-me, igualmente, de Polarizações hierarquizadas como fonte/alvo, situando-me na fronteira fluida do transformar de escritas/reescritas e nela privilegiando áreas de permeabilidade entre os discursos e o seu jogo relacional, ofereço, neste texto, reflexões em torno da poesia metafísica inglesa traduzida entre 1978 e 1991 na sua interseção com outras produções textuais brasileiras no período de início da abertura política, gestação e nascimento da Nova República2 . Traduzir a Inglaterra, ler o Brasil. O que se traduz? Quem se traduz? Por que se traduz? Como se traduz?

  13. Os três maiores “equívocos” na Teoria da Relatividade de Einstein

    Directory of Open Access Journals (Sweden)

    Roberto A. Monti

    1999-05-01

    Full Text Available É chegado o momento de esclarecer os três maiores “equívocos” comumente ensinados nas escolas e universidades em todo o mundo: 1. Os experimentos de Michelson-Morley-Miller nunca deram um “resultado nulo”, contrariamente ao que é estabelecido na maioria dos livros-textos de física. 2. Os resultados experimentais do eclipse solar de 1919 nunca “provaram” a teoria da Relatividade (Geral de Einstein. A “diferença” entre a deflexão Newtoniana e a Einsteiniana de um feixe de luz nunca foram “confirmadas” após 1919. Pelo contrário, em 1960, resultados experimentais obtidos por Pound e Rebka mostraram que a energia (ou massa da luz está sujeita à gravitação Newtoniana da mesma forma que a matéria comum. 3. O “Big Bang” nunca ocorreu. Evidências experimentais mostram que Hubble e Nernst provaram claramente que o Universo não está se expandindo. Este resultado tem sido sempre confirmado por dados astrofísicos e pela física elementar.

  14. Flexural Properties of E Glass and TR50S Carbon Fiber Reinforced Epoxy Hybrid Composites

    Science.gov (United States)

    Dong, Chensong; Sudarisman; Davies, Ian J.

    2013-01-01

    A study on the flexural properties of E glass and TR50S carbon fiber reinforced hybrid composites is presented in this paper. Specimens were made by the hand lay-up process in an intra-ply configuration with varying degrees of glass fibers added to the surface of a carbon laminate. These specimens were then tested in the three-point bend configuration in accordance with ASTM D790-07 at three span-to-depth ratios: 16, 32, and 64. The failure modes were examined under an optical microscope. The flexural behavior was also simulated by finite element analysis, and the flexural modulus, flexural strength, and strain to failure were calculated. It is shown that although span-to-depth ratio shows an influence on the stress-strain relationship, it has no effect on the failure mode. The majority of specimens failed by either in-plane or out-of-plane local buckling followed by kinking and splitting at the compressive GFRP side and matrix cracking combined with fiber breakage at the CFRP tensile face. It is shown that positive hybrid effects exist for the flexural strengths of most of the hybrid configurations. The hybrid effect is noted to be more obvious when the hybrid ratio is small, which may be attributed to the relative position of the GFRP layer(s) with respect to the neutral plane. In contrast to this, flexural modulus seems to obey the rule of mixtures equation.

  15. Três lições de filosofia da educação

    Directory of Open Access Journals (Sweden)

    Kohan Walter Omar

    2003-01-01

    Full Text Available O presente trabalho busca pensar o valorde O mestre ignorante como exercício de filosofia da educação, em particular contrapondo-o a um modo, dominante, de exercer esse saber no seio de nossas instituições. Trata-se de uma história singular, pela qual todo mestre pode se perguntar por que e para que ensina; e, o que é ainda mais importante, pela qual pode questionar-se que diabos está fazendo consigo mesmo e com os outros, a cada vez que se veste de mestre em uma sala de aula. Depreendemos, desse exercício, três lições: a o mais natural, evidente e aceito socialmente acaba sendo, filosoficamente, o mais problemático; b somente pelo paradoxo, entranhados no lodo paradoxal, podemos encontrar algum sentido na educação; c só há uma educação que vale a pena: a que emancipa (sem emancipar. Quem não deixa que os(as outros(as se emancipem embrutece.

  16. Conceito de parceria: três projectos locais de promoção do emprego

    Directory of Open Access Journals (Sweden)

    Tiago Carrilho

    2008-01-01

    Full Text Available Neste estudo analisam-se as práticas de parceria em três projectos de promoção do emprego. Define-se parceria como o processo através do qual dois ou mais actores se relacionam na base de pressupostos-chave que têm tradução na dinâmica subjacente a determinado projecto. Nos projectos analisados, À Medida, Formart e Le Cheile, o trabalho em parceria traduz-se no envolvimento dos agentes institucionais na disponibilização de recursos, na articulação das tarefas e nas mudanças organizacionais. Esta base permite a promoção local do emprego numa perspectiva de maior integração social.This study analyzes partnership practices in three job promotion projects. Partnership is defined as a process in which two or more actors are associated on the basis of key assumptions which are reflected in the underlying dynamics of a given project. For the three projects analyzed, À Medida, Formart and Le Cheile, partnership work emerges in institutional actors' involvement in making resources available, in task co-ordination and in organizational change. This foundation makes it possible to promote employment within a wider scheme aimed at achieving social inclusion.

  17. The School Anxiety Scale-Teacher Report (SAS-TR): translation and psychometric properties of the Iranian version.

    Science.gov (United States)

    Hajiamini, Zahra; Mohamadi, Ashraf; Ebadi, Abbas; Fathi- Ashtiani, Ali; Tavousi, Mahmoud; Montazeri, Ali

    2012-07-18

    The School Anxiety Scale-Teacher Report (SAS-TR) was designed to assess anxiety in children at school. The SAS-TR is a proxy rated measure and could assess social anxiety, generalized anxiety and also gives a total anxiety score. This study aimed to translate and validate the SAS-TR in Iran. The translation and cultural adaptation of the original questionnaire were carried out in accordance with the published guidelines. A sample of students participated in the study. Reliability was estimated using internal consistency and test-retest analysis. Validity was assessed using content validity. The factor structure of the questionnaire was extracted by performing both exploratory and confirmatory factor analyses. In all 200 elementary students aged 6 to 10 years were studied. Considering the recommended cut-off values, overall the prevalence of high anxiety condition in elementary students was found to be 21 %. Cronbach's alpha coefficient for the Iranian SAS-TR was 0.92 and intraclass correlation coefficient (ICC) was found to be 0.81. The principal component analysis indicated a two-factor structure for the questionnaire (generalized and social anxiety) that jointly accounted for 55.3 % of variances observed. The confirmatory factory analysis also indicated a good fit to the data for the two-latent structure of the questionnaire. In general the findings suggest that the Iranian version of SAS-TR has satisfactory reliability, and validity for measuring anxiety in 6 to 10 years old children in Iran. It is simple and easy to use and now can be applied in future studies.

  18. The School Anxiety Scale-Teacher Report (SAS-TR: translation and psychometric properties of the Iranian version

    Directory of Open Access Journals (Sweden)

    Hajiamini Zahra

    2012-07-01

    Full Text Available Abstract Background The School Anxiety Scale-Teacher Report (SAS-TR was designed to assess anxiety in children at school. The SAS-TR is a proxy rated measure and could assess social anxiety, generalized anxiety and also gives a total anxiety score. This study aimed to translate and validate the SAS-TR in Iran. Methods The translation and cultural adaptation of the original questionnaire were carried out in accordance with the published guidelines. A sample of students participated in the study. Reliability was estimated using internal consistency and test-retest analysis. Validity was assessed using content validity. The factor structure of the questionnaire was extracted by performing both exploratory and confirmatory factor analyses. Results In all 200 elementary students aged 6 to 10 years were studied. Considering the recommended cut-off values, overall the prevalence of high anxiety condition in elementary students was found to be 21 %. Cronbach's alpha coefficient for the Iranian SAS-TR was 0.92 and intraclass correlation coefficient (ICC was found to be 0.81. The principal component analysis indicated a two-factor structure for the questionnaire (generalized and social anxiety that jointly accounted for 55.3 % of variances observed. The confirmatory factory analysis also indicated a good fit to the data for the two-latent structure of the questionnaire. Conclusion In general the findings suggest that the Iranian version of SAS-TR has satisfactory reliability, and validity for measuring anxiety in 6 to 10 years old children in Iran. It is simple and easy to use and now can be applied in future studies.

  19. Análise dos acidentes de trânsito ocorridos em uma Capital do Nordeste Brasileiro, em 2006.

    Directory of Open Access Journals (Sweden)

    Francisco José de Paula Júnior

    2013-06-01

    Full Text Available Este trabalho teve como objetivo descrever os acidentes de trânsito ocorridos na cidade de Fortaleza, capital do Ceará, no ano de 2006. Foi realizado um estudo descritivo, transversal, a partir de dados do Sistema de Informação de Acidentes de Trânsito de Fortaleza, que agrega todas as informações pertinentes aos acidentes de trânsito ocorridos na capital cearense, além de informações do Sistema de Informações Hospitalares. Esses dados foram analisados utilizando o software EPI INFO®. Em 2006, foram registrados 23.443 acidentes de trânsito. Desses, houve uma proporção de 2:1, entre homens e mulheres e os óbitos ocorreram principalmente na faixa etária de 30 a 59 anos, liderados por pedestres 141 (41,34% e motociclistas com 76 (22,28%. Entre os tipos de acidentes 14.267 (60,85% registraram-se colisões, tendo o mês de dezembro e o intervalo de 18 às 20 horas apresentado o maior número de registros. Em relação aos ferimentos, os motociclistas foram os mais lesionados, atingindo 5.634 (40,57% pessoas. Parte significativa dos acidentes e óbitos envolveu adolescentes e adultos jovens, resultando em 341 (0,71% vitimas que evoluíram para óbito. É fundamental estimular políticas públicas para melhoria nas condições de trânsito e um maior investimento para os sistemas que coletam informações sobre os acidentes.

  20. Genomic and proteomic analysis of the Alkali-Tolerance Response (AlTR in Listeria monocytogenes 10403S

    Directory of Open Access Journals (Sweden)

    Wilkinson Brian J

    2008-06-01

    Full Text Available Abstract Background Information regarding the Alkali-Tolerance Response (AlTR in Listeria monocytogenes is very limited. Treatment of alkali-adapted cells with the protein synthesis inhibitor chloramphenicol has revealed that the AlTR is at least partially protein-dependent. In order to gain a more comprehensive perspective on the physiology and regulation of the AlTR, we compared differential gene expression and protein content of cells adapted at pH 9.5 and un-adapted cells (pH 7.0 using complementary DNA (cDNA microarray and two-dimensional (2D gel electrophoresis, (combined with mass spectrometry respectively. Results In this study, L. monocytogenes was shown to exhibit a significant AlTR following a 1-h exposure to mild alkali (pH 9.5, which is capable of protecting cells from subsequent lethal alkali stress (pH 12.0. Adaptive intracellular gene expression involved genes that are associated with virulence, the general stress response, cell division, and changes in cell wall structure and included many genes with unknown functions. The observed variability between results of cDNA arrays and 2D gel electrophoresis may be accounted for by posttranslational modifications. Interestingly, several alkali induced genes/proteins can provide a cross protective overlap to other types of stresses. Conclusion Alkali pH provides therefore L. monocytogenes with nonspecific multiple-stress resistance that may be vital for survival in the human gastrointestinal tract as well as within food processing systems where alkali conditions prevail. This study showed strong evidence that the AlTR in L. monocytogenes functions as to minimize excess alkalisation and energy expenditures while mobilizing available carbon sources.

  1. Klatring i trær og hyttebygging: - om barns lek og lekesteder ute

    Directory of Open Access Journals (Sweden)

    Merete Lund Fasting

    2015-07-01

    Full Text Available Abstract: This article describes 10 year old children`s play in nature during school hours. However, my result does equally reflect on children in kindergarden as well. Observation and conversation was used as methods as well as pictures. The children’s play in the trees and building huts was conducted in groups, and their communication was nonverbal with each other and with the nature. However; the girls reveal that they enjoy their conversations while being in the tree. The children often play at the same place over and over. This is significant to the evolution of the play and the children’s communication with their places in nature.Sammendrag: Denne artikkelen omhandler 10 år gamle barns lek på natursteder i skoletida. Selv om studien omhandler 10 åringer så kan kunnskapen den frembringer også være viktig for å forstå barnehagebarns lek og tilknytning til sine lekesteder i barnehagen. Metodene som ble brukt for å undersøke barnas lek var observasjoner og samtaler med barna, i tillegg til fotografier. Barnas lek i trærne og i hyttebyggingen karakteriseres ved at de er flere sammen, og barna har en kroppslig dialog med hverandre og omgivelsene i leken. Barna snakker i liten grad sammen om leken og hvordan de skal leke; deres kommunikasjon er hovedsakelig nonverbal. Men når jentene sitter i treet forteller de meg at de liker å sitte og snakke. Barna leker på steder hvor de har vært mye før, og dette har en betydning for barnas lek og barnas kommunikasjon med deres steder.

  2. Confiabilidade estrutural de uma ponte protendida de madeira considerando o tráfego real

    Directory of Open Access Journals (Sweden)

    Andrés Batista Cheung

    Full Text Available Resumo As pontes protendidas de madeira consistem em sistemas estruturais alternativos, mais leves do que as pontes tradicionais, e apresentam grande rigidez e facilidade de montagem. No Brasil a primeira ponte protendida de madeira foi projetada e construída sobre o Rio Monjolinho, em São Carlos, SP. A confiabilidade desse tipo de estrutura é um dos pontos de maior preocupação técnica, embora essa forma de avaliação ainda não seja utilizada em projetos de pontes de madeira. Este trabalho objetivou avaliar a confiabilidade estrutural do sistema laminado protendido de madeira da ponte projetada sobre o Rio Monjolinho, com foco especial na resistência à flexão e na perda de protensão do sistema, considerando-se para tanto um conjunto variado de trens-tipo. O tabuleiro foi avaliado como uma viga equivalente, baseado no comportamento de placa ortotrópica, e para verificar a segurança da ponte um estudo de confiabilidade foi realizado considerando ações reais obtidas por meio dos dados da concessionária Centrovias. Os resultados das análises de confiabilidade revelaram que a ponte protendida de madeira apresentou índices de confiabilidade compatíveis para a maioria dos carregamentos simulados do tráfego, embora para alguns tipos de caminhões a ponte tenha apresentado índices de confiabilidade abaixo do recomendado pelas normas internacionais.

  3. Exílio: uma história em três dimensões

    Directory of Open Access Journals (Sweden)

    Heloisa Paulo

    2014-06-01

    Full Text Available No século XX, a ascensão dos regimes fascistas leva ao exílio opositores que procuravam fugir da morte pela execução sumária ou pelo confinamento aos campos de concentração. Portugal conhece um dos mais longos regimes de força, levando seus opositores a um longo degredo que, para uma grande maioria, durou toda a vida. Estes exilados e emigrados políticos buscaram refúgio nas mais diferentes partes do mundo, quer nos antigos núcleos de emigração ou em países onde o Estado democrático favorecia seu acolhimento. E se as histórias de vida exigem a recuperação de diversos "espaços históricos", no caso dos exilados estes "espaços" possuem uma outra dimensão. À dimensão local, origem e formação dos personagens e ao contexto do "nacional", em que estão inseridos num momento de maioridade, podemos acrescentar outro, "supranacional", ou seja, a história dos países de acolhimento, uma base para a compreensão das relações estabelecidas no exílio. Tomando como ponto de partida o caso português, este trabalho pretende ressaltar alguns pontos importantes para a elaboração de biografias de exilados, tendo-se em conta a necessidade de cruzamento dos três espaços citados, a releitura da historiografia já produzida e os problemas da "memória oficial".

  4. Concordance of DSM-5 and DSM-IV-TR classifications for autism spectrum disorder.

    Science.gov (United States)

    Ohashi, Kei; Mizuno, Yoshifumi; Miyachi, Taishi; Asai, Tomoko; Imaeda, Masayuki; Saitoh, Shinji

    2015-12-01

    The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) was published in May 2013. Autism spectrum disorder (ASD) has been structured for the three subtypes of pervasive developmental disorder (PDD), but the number of impairment in social and communication dimension is not stated. The subjects were 68 children who visited the Department of Psychology and Development at Nagoya City University Hospital for the first time between the ages of 6 and 15 years old. We retrospectively re-examined the subjects using DSM-IV-TR criteria and DSM-5 criteria with two rules (two of three and one of three on the social and communication dimension) and examined the concordance rate. Forty subjects were diagnosed with PDD, and 28 were not. The mean PDD subject age was 9.4 years, and mean IQ was 84.0 on the Wechsler Intelligence Scale for Children III or 62.7 on the Tanaka-Binet test. Twenty-seven (68%) of the PDD subjects were classified with ASD using DSM-5 criteria when the two of three rule was applied, while 32 (80%) were classified with ASD when the one of three rule was applied. All subjects without PDD were not diagnosed with ASD on DSM-5 criteria. DSM-5 criteria may exclude high functioning and older subjects from ASD because they tend to be atypical. The diagnostic procedure for DSM-5 criteria is ambiguous, especially in high functioning subjects and those diagnosed at an older age. © 2015 Japan Pediatric Society.

  5. Vulnerabilidade humana no contexto do trânsito motociclístico

    Directory of Open Access Journals (Sweden)

    Marcelo Moreira Corgozinho

    Full Text Available Resumo O aspecto fundamental da vulnerabilidade enquanto princípio ético da Declaração Universal sobre Bioética e Direitos Humanos é o de formular uma obrigação de ação moral diante das situações que fragilizam determinados grupos da sociedade. Nesse sentido, este estudo objetiva promover uma reflexão, a partir do princípio do respeito pela vulnerabilidade humana, utilizando como público-alvo motociclistas e sua experiência com o uso da moto. Trata-se de estudo com abordagem qualitativa, utilizando metodologia quantiqualitativa para análise das entrevistas dos participantes. A partir da experiência dos motociclistas com a utilização da motocicleta foi possível apresentar alguns apontamentos que vão ao encontro da necessidade de respeito pela vulnerabilidade humana, a saber: potencialização da vulnerabilidade intrínseca ao ser humano; vulnerabilidade social; e responsabilidade social do Estado diante da utilização da motocicleta. Ao considerar o respeito pela vulnerabilidade humana e a utilização da motocicleta, torna-se necessário correlacionar aspectos que envolvam a responsabilidade social com situações de suscetibilidade humana ao agravo. Assim, torna-se fundamental a implementação de políticas de intervenção que abarquem as dimensões econômica, cultural e política, por meio da intersetorialidade, para que se consiga alcançar efetivamente todos os atores envolvidos na dinâmica da segurança do trânsito motociclístico: Estado, autoridades de fiscalização, fabricantes de veículos, condutores, pedestres e ciclistas.

  6. Agressividade de três raças de Cercospora sojina em folhas de soja

    Directory of Open Access Journals (Sweden)

    Juliane Nicolodi Camera

    2014-06-01

    Full Text Available Este trabalho teve como objetivo avaliar a patogenicidade e a agressividade de três raças de Cercospora sojina, em dois cultivares de soja, BMX Magna e Bragg. Para isso, preparou-se suspensão, na concentração de 40 x 10³ conídio mL-1, para inoculação das plantas. Quinze dias após a inoculação com o fungo, verificou-se que a severidade e o número de lesões por folíolo, para a raça 23, não apresentaram diferenças estatísticas entre os cultivares. Para as raças 24 e 25, o cultivar BMX Magna apresentou maior valor do grau de infecção, diferindo estatisticamente daquele do cultivar Bragg. Com relação ao diâmetro das lesões, para a raça 23, o cultivar Bragg apresentou maior valor, para a raça 24, o maior valor ocorreu em BMX Magna e para a raça 25, não houve diferença estatística entre os cultivares. Portanto, as raças de C. sojina são patogênicas para os dois cultivares de soja e há diferença de agressividade entre elas, sendo as raças 24 e 25 mais agressivas do que a raça 23.

  7. Genome Sequencing and Comparative Analysis of the Biocontrol Agent Trichoderma harzianum sensu stricto TR274

    Energy Technology Data Exchange (ETDEWEB)

    Steindorff, Andrei S.; Noronha, Elilane F.; Ulhoa, Cirano J.; Kuo, Alan; Salamov, Asaf A.; Haridas, Sajeet; Riley, Robert W.; Druzhinina, Irina S.; Kubicek, Christian P.; Grigoriev, Igor V.

    2015-03-17

    Biological control is a complex process which requires many mechanisms and a high diversity of biochemical pathways. The species of Trichoderma harzianum are well known for their biocontrol activity against many plant pathogens. To gain new insights into the biocontrol mechanism used by T. harzianum, we sequenced the isolate TR274 genome using Illumina. The assembly was performed using AllPaths-LG with a maximum coverage of 100x. The assembly resulted in 2282 contigs with a N50 of 37033bp. The genome size generated was 40.8 Mb and the GC content was 47.7%, similar to other Trichoderma genomes. Using the JGI Annotation Pipeline we predicted 13,932 genes with a high transcriptome support. CEGMA tests suggested 100% genome completeness and 97.9% of RNA-SEQ reads were mapped to the genome. The phylogenetic comparison using orthologous proteins with all Trichoderma genomes sequenced at JGI, corroborates the Trichoderma (T. asperellum and T. atroviride), Longibrachiatum (T. reesei and T. longibrachiatum) and Pachibasium (T. harzianum and T. virens) section division described previously. The comparison between two Trichoderma harzianum species suggests a high genome similarity but some strain-specific expansions. Analyses of the secondary metabolites, CAZymes, transporters, proteases, transcription factors were performed. The Pachybasium section expanded virtually all categories analyzed compared with the other sections, specially Longibrachiatum section, that shows a clear contraction. These results suggests that these proteins families have an important role in their respective phenotypes. Future analysis will improve the understanding of this complex genus and give some insights about its lifestyle and the interactions with the environment.

  8. TR PIV Experimental Investigation on Bypass Transition Induced by a Cylinder Wake

    International Nuclear Information System (INIS)

    Tang Zhan-Qi; Jiang Nan

    2011-01-01

    The process of laminar to turbulent transition induced by a cylinder wake is studied by time-resolved (TR) particle image velocimetry (PIV) in a water channel. The combination of multi-scale local-averaged structure function analysis with criteria is used to identify the generation of secondary transverse vortex structure and to track its evolution along the streamwise. At the beginning of transition, with the decent of cylinder wake vortex, the secondary vortex structure is induced near the wall. As the secondary vortex moves downstream, it is induced to lift up by the wake vortex, meanwhile they are diffused and dissipated. According to the method of spatial conditional average, a low-speed hump is found in the near-wall region along the bypass transition zone, accompanied by a low-speed region in the free stream occupied by the wake vortex. With further downstream, the hump in the near-wall region becomes more and more obvious. At the later stage of transition zone, hairpin vortex can be seen by conditional-averaged low-pass filtered vorticity. The hairpin head is almost vertical to the wall with an inclination angle of about 90°, which is attributed to the additional lift-up behavior induced by wake vortex. It can be concluded that in the process of bypass transition, the wake vortex would not only induce the secondary vortex but also leaven its growth and evolution, resulting in the robust and rapidly growing hairpin vortex. (fundamental areas of phenomenology(including applications))

  9. MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate cancer.

    Science.gov (United States)

    Baena-Del Valle, Javier A; Zheng, Qizhi; Esopi, David M; Rubenstein, Michael; Hubbard, Gretchen K; Moncaliano, Maria C; Hruszkewycz, Andrew; Vaghasia, Ajay; Yegnasubramanian, Srinivasan; Wheelan, Sarah J; Meeker, Alan K; Heaphy, Christopher M; Graham, Mindy K; De Marzo, Angelo M

    2018-01-01

    Telomerase consists of at least two essential elements, an RNA component hTR or TERC that contains the template for telomere DNA addition and a catalytic reverse transcriptase (TERT). While expression of TERT has been considered the key rate-limiting component for telomerase activity, increasing evidence suggests an important role for the regulation of TERC in telomere maintenance and perhaps other functions in human cancer. By using three orthogonal methods including RNAseq, RT-qPCR, and an analytically validated chromogenic RNA in situ hybridization assay, we report consistent overexpression of TERC in prostate cancer. This overexpression occurs at the precursor stage (e.g. high-grade prostatic intraepithelial neoplasia or PIN) and persists throughout all stages of disease progression. Levels of TERC correlate with levels of MYC (a known driver of prostate cancer) in clinical samples and we also show the following: forced reductions of MYC result in decreased TERC levels in eight cancer cell lines (prostate, lung, breast, and colorectal); forced overexpression of MYC in PCa cell lines, and in the mouse prostate, results in increased TERC levels; human TERC promoter activity is decreased after MYC silencing; and MYC occupies the TERC locus as assessed by chromatin immunoprecipitation (ChIP). Finally, we show that knockdown of TERC by siRNA results in reduced proliferation of prostate cancer cell lines. These studies indicate that TERC is consistently overexpressed in all stages of prostatic adenocarcinoma and that its expression is regulated by MYC. These findings nominate TERC as a novel prostate cancer biomarker and therapeutic target. Copyright © 2017 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd. Copyright © 2017 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

  10. Chimeric bispecific OC/TR monoclonal antibody mediates lysis of tumor cells expressing the folate-binding protein (MOv18) and displays decreased immunogenicity in patients

    NARCIS (Netherlands)

    Luiten, R. M.; Warnaar, S. O.; Sanborn, D.; Lamers, C. H.; Bolhuis, R. L.; Litvinov, S. V.; Zurawski, V. R.; Coney, L. R.

    1997-01-01

    The bispecific OC/TR monoclonal antibody (mAb) cross-links the CD3 molecule on T cells with the human folate-binding protein (FBP), which is highly expressed on nonmucinous ovarian carcinomas. Clinical trials of patients with ovarian carcinoma with the OC/TR mAb have shown some complete and partial

  11. Investigation of a solar heating system for space heating and domestic hot water supply for Sol&Træ A.m.b.a

    DEFF Research Database (Denmark)

    Vejen, Niels Kristian

    1999-01-01

    A solar heating system for space heating and domestic hot water supply from "Sol&Træ A.m.b.a." was tested in a laboratory test facility.......A solar heating system for space heating and domestic hot water supply from "Sol&Træ A.m.b.a." was tested in a laboratory test facility....

  12. The potential of chitosan in enhancing peptide and protein absorption across the TR146 cell culture model-an in vitro model of the buccal epithelium

    DEFF Research Database (Denmark)

    Portero, Ana; Remuñán-López, Carmen; Nielsen, Hanne Mørck

    2002-01-01

    To investigate the potential of chitosan (CS) to enhance buccal peptide and protein absorption, the TR146 cell culture model, a model of the buccal epithelium, was used.......To investigate the potential of chitosan (CS) to enhance buccal peptide and protein absorption, the TR146 cell culture model, a model of the buccal epithelium, was used....

  13. Uniprindi büroo- ja trükikojahoone : edu peatänavatest, Uniprindi trükikojast ning geneerilisest arhitektuurist = Success from Main Streets, Uniprint Printing Plant, and Generic Architecture / Veljo Kaasik

    Index Scriptorium Estoniae

    Kaasik, Veljo

    2000-01-01

    Pärnu mnt. ristmiku juurde Tallinnas R. Puusepa arhitektibüroo poolt trükikojale Uniprint projekteeritud büroo-tootmishoonest. Arhitektid Raivo Puusepp, Krista Väärtnõu. Konstruktsioonid: Projektbüroo Teinos, Civen OÜ. Projekt 1999-2000, hoone valmis 2000. Peatänavaid ääristava hoonestuse kiirest muundumisest. 9 ill.: korruste plaanid, lõiked, vaated (joon.); välisvaated (foto)

  14. Adquisición de variables de tráfico vehicular usando visión por computador

    OpenAIRE

    Germán Enrique Urrego; Francisco Carlos Calderón; Alejandro Forero; Julián Armando Quiroga

    2009-01-01

    El conteo de vehículos es una tarea fundamental en los aforos de tráfico, tanto para el diseño de nuevas vías como para el control y la optimización del tráfico urbano. En ciudades como Bogotá, este conteo actualmente se realiza en forma manual, pero puede hacerse automáticamente empleando técnicas de visión por computador. El presente artículo muestra el desarrollo de un algoritmo de detección y seguimiento de vehículos en tiempo real a partir de video, el cual permite el conteo de vehículos...

  15. O pluralismo da tese dos três mundos de Popper e a crí­tica de Habermas

    Directory of Open Access Journals (Sweden)

    João Batista C. Sieczkowski

    2010-09-01

    Full Text Available Este estudo abordará a tese dos três mundos, TTM, de Karl Popper. A TTM como pluralista e interacionista opõe-se ao monismo e a algumas concepções dualistas. Em uma segunda parte, pretendemos enfocar a crítica de Jürgen Habermas quando tenta aplicar a TTM e o M3 (mundo três na obtençáo de uma justificaçáo da teoria da açáo para a sociologia. Nesta crítica Habermas acaba negligenciando muitos objetivos claros da TTM e do M3 descritos por Popper, principalmente quando náo considera a TTM como uma tese metafísica e como resposta ao problema corpo-mente.

  16. Uma Abordagem de Monitoração de Tráfego de Rede utilizando Lógica Difusa

    OpenAIRE

    Silveira, Enio Rovere; Universidade Federal de Santa Catarina; Dantas, M. A.R.; Universidade Federal de Santa Catarina

    2005-01-01

    Neste artigo, apresentamos um trabalho de pesquisa de monitoração de tráfego de rede utilizando uma abordagem de lógica difusa. Nossa contribuição está focada na criação de um protótipo que pudesse ser avaliado em uma configuração real de produção de uma grande organização, utilizando-se de hardware e software existentes na empresa. Resultados experimentais obtidos através de estudos de casos reais no ambiente, indicam o sucesso da abordagem na melhoria da monitoração de tráfego da rede....

  17. Deep Sequencing Transcriptome Analysis of Murine Wound Healing: Effects of a Multicomponent, Multitarget Natural Product Therapy-Tr14.

    Science.gov (United States)

    St Laurent, Georges; Seilheimer, Bernd; Tackett, Michael; Zhou, Jianhua; Shtokalo, Dmitry; Vyatkin, Yuri; Ri, Maxim; Toma, Ian; Jones, Dan; McCaffrey, Timothy A

    2017-01-01

    Wound healing involves an orchestrated response that engages multiple processes, such as hemostasis, cellular migration, extracellular matrix synthesis, and in particular, inflammation. Using a murine model of cutaneous wound repair, the transcriptome was mapped from 12 h to 8 days post-injury, and in response to a multicomponent, multi-target natural product, Tr14. Using single-molecule RNA sequencing (RNA-seq), there were clear temporal changes in known transcripts related to wound healing pathways, and additional novel transcripts of both coding and non-coding genes. Tr14 treatment modulated >100 transcripts related to key wound repair pathways, such as response to wounding, wound contraction, and cytokine response. The results provide the most precise and comprehensive characterization to date of the transcriptome's response to skin damage, repair, and multicomponent natural product therapy. By understanding the wound repair process, and the effects of natural products, it should be possible to intervene more effectively in diseases involving aberrant repair.

  18. Comparison of DSM-IV-TR and DSM-5 Criteria in Diagnosing Autism Spectrum Disorders in Singapore.

    Science.gov (United States)

    Sung, Min; Goh, Tze Jui; Tan, Bei Lin Joelene; Chan, Jialei Stephanie; Liew, Hwee Sen Alvin

    2018-04-28

    Our study examines the Diagnostic and Statistical Manual-Fifth Edition (DSM-5) and Diagnostic and Statistical Manual-Fourth Edition, Text Revision (DSM-IV-TR) when applied concurrently against the best estimate clinical diagnoses for 110 children (5.1-19.6 years old) referred for diagnostic assessments of Autism Spectrum Disorder (ASD) in a Singaporean outpatient speciality clinic. DSM-IV-TR performed slightly better, yielding sensitivity of 0.946 and specificity of 0.889, compared to DSM-5 (sensitivity = 0.837; specificity = 0.833). When considering the ASD sub-categories, sensitivity ranged from 0.667 to 0.933, and specificity ranged from 0.900 to 0.975. More participants with a PDD-NOS best estimate clinical diagnosis (40%) were misclassified on DSM-5. Merits and weaknesses to both classification systems, and implications for access to services and policy changes are discussed.

  19. Mesure de vitesse acoustique dans un écoulement de conduite turbulent par LDV et TR-PIV

    OpenAIRE

    Léon , Olivier; Piot , Estelle; Sebbane , Delphine; Simon , Frank

    2016-01-01

    International audience; Ces travaux visent à montrer la faisabilité de la mesure de composantes de vitesse acoustique, i.e. amplitude et phase, dans un écoulement de conduite pleinement turbulent par TR-PIV et LDV, pour des conditions d’essais présentant des amplitudes sonores d’au moins 130dB, des nombres de Mach de l’ordre de 0.1 et des taux de turbulence supérieurs à 5%. L’objectif à long terme est de mettre en oeuvre la technique TR-PIV dans des conditions d’essais rencontrées dans l’étud...

  20. Uso de redes neuronales artificiales para mejorar el tránsito en las vías

    Directory of Open Access Journals (Sweden)

    Edwin Mejía

    2016-11-01

    Full Text Available Este artículo pretende dar una idea de cómo las Redes Neuronales Artificiales (ANNs, una técnica de la Inteligencia Artificial (IA, se puede acoplar a resolver el problema del tráfico en las vías de la ciudad de Riobamba, provincia de Chimborazo, país Ecuador, usando cuatro semáforos estándar, a través de un ejemplo se indica el uso de componentes electrónicos como FPGAs (Field Programmable Gate array y los sensores en este campo, a través de detectar y contar autos puede dar mayor fluidez al tráfico. La vía que mayor cantidad de autos tenga se dará mayor prioridad para la luz verde. Usando el algoritmo de aprendizaje de un Perceptrón Simple.

  1. Poblaciones-Mercancía: Tráfico y trata de mujeres en España

    OpenAIRE

    García Cuesta, Sara; López Sala, Ana María; Hernández Corrochano, Elena; Mena Martínez, Luis

    2011-01-01

    Se trata de la primera publicación que hace la Delegación del Gobierno para la Violencia de Género a fin de ahondar en el fenómeno de la Trata de Seres Humanos con fines de explotación sexual. El estudio refleja la situación en España de las mujeres que han sido víctimas del tráfico y de la trata de seres humanos con fines de explotación sexual, trazando de manera firme la diferencia entre tráfico de personas y trata de mujeres con fines de explotación sexual.

  2. Tráfico de animais: o que dizem os alunos do ensino médio?

    Directory of Open Access Journals (Sweden)

    Lucas Loram Lourenço

    2017-07-01

    Full Text Available O tráfico de animais é todo comércio ilegal de espécies nativas de uma determinada região, o que muitas vezes passa despercebido pela sociedade. Neste sentido, o presente trabalho teve como objetivo compreender as concepções de alunos do Ensino Médio sobre o tráfico de animais silvestres, considerando a escola como um espaço de disseminação de saberes, e reportando que a mesma deve atuar discutindo questões como esta, de modo a levar o alunado a uma visão crítica reflexiva. A pesquisa se caracteriza como qualitativa, e mediante seu objetivo, como estudo de caso. O objeto de coleta de dados foi o questionário, aplicado a alunos da 3º série do Ensino Médio de uma escola da rede pública da cidade de Montes Claros de Goiás – GO. Foi possível notar que, mesmo conhecendo a ilegalidade e também as injúrias causadas pelo tráfico, ainda existe uma parcela de alunos que possuem animais silvestres em cativeiro. Nesse ponto, ressalta-se a necessidade de que a escola volte seu olhar para a temática, a fim de sensibilizar a população sobre a importância de se evitar condutas que fomentem o tráfico de animais.

  3. Relaciones tróficas entre los macroinvertebrados y peces en un arroyo de la llanura pampeana (Argentina)

    OpenAIRE

    López van Oosterom, María V.; Ocón, Carolina S.; Brancolini, Florencia; Maroñas, Miriam E.; Sendra, Eduardo D.; Rodrigues Capítulo, Alberto

    2013-01-01

    Se evaluó la dieta y las relaciones tróficas entre los macroinvertebrados Phyllogomphoides joaquini Rodrigues Capítulo, 1992 y Coenagrionidae (Odonata), Chironomidae (Diptera), Diplodon delodontus (Lamarck, 1919) (Bivalvia: Hyriidae), Pomacea canaliculata (Lamarck, 1822) (Gastropoda: Ampulariidae) y los peces Pimelodella laticeps Eigenmann, 1917 (Heptapteridae) y Bryconamericus iheringii (Boulenger, 1887) (Characidae) en un ecosistema lótico pampásico, sobre la base del contenido estomacal y ...

  4. Combined lymphangioma and hemangioma of the spleen in a patient with Klippel–Trénaunay syndrome

    OpenAIRE

    Spasić Marko; Radovanović Dragče; Čanović Dragan; Azanjac Goran; Đurđević Predrag; Mitrović Slobodanka

    2012-01-01

    Introduction. Klippel–Trénaunay syndrome (KTS) is a very rare congenital anomaly of blood vessels, characterized by the following clinical triad: varicose superficial veins, port-wine stain and usually bony and soft tissue hypertophy of extremities, most often located in the lower extremities. It is often accompanied by visceral manifestations, and rarely combined with splenomegaly. Case Outline. A 30-year-old female patient came to the Surgery Clinic because of occasional left hypochon...

  5. Parasitoses Intestinais Como Causa de Anemia na Gravidez: Três Casos Clínicos Ilustrativos

    OpenAIRE

    Reis, D; Vicente, L; Borges, A

    2001-01-01

    Os autores apresentam três casos clínicos de parasitoses, diagnosticadas no contexto de anemia. A propósito destas situações é feita uma revisão teórica das infestações em causa - shistosomíase, ancilostomíase, giardíase, trichiuríase e ascaridíase.

  6. Comparison of ICD-10R, DSM-IV-TR and DSM-5 in an Adult Autism Spectrum Disorder Diagnostic Clinic

    Science.gov (United States)

    Wilson, C. Ellie; Gillan, Nicola; Spain, Deborah; Robertson, Dene; Roberts, Gedeon; Murphy, Clodagh M.; Maltezos, Stefanos; Zinkstok, Janneke; Johnston, Katie; Dardani, Christina; Ohlsen, Chris; Deeley, P. Quinton; Craig, Michael; Mendez, Maria A.; Happé, Francesca; Murphy, Declan G. M.

    2013-01-01

    An Autism Spectrum Disorder (ASD) diagnosis is often used to access services. We investigated whether ASD diagnostic outcome varied when DSM-5 was used compared to ICD-10R and DSM-IV-TR in a clinical sample of 150 intellectually able adults. Of those diagnosed with an ASD using ICD-10R, 56% met DSM-5 ASD criteria. A further 19% met DSM-5 (draft)…

  7. Orphan nuclear receptor TR3/Nur77 regulates VEGF-A–induced angiogenesis through its transcriptional activity

    OpenAIRE

    Zeng, Huiyan; Qin, Liuliang; Zhao, Dezheng; Tan, Xiaolian; Manseau, Eleanor J.; Van Hoang, Mien; Senger, Donald R.; Brown, Lawrence F.; Nagy, Janice A.; Dvorak, Harold F.

    2006-01-01

    Vascular endothelial growth factor (VEGF)-A has essential roles in vasculogenesis and angiogenesis, but the downstream steps and mechanisms by which human VEGF-A acts are incompletely understood. We report here that human VEGF-A exerts much of its angiogenic activity by up-regulating the expression of TR3 (mouse homologue Nur77), an immediate-early response gene and orphan nuclear receptor transcription factor previously implicated in tumor cell, lymphocyte, and neuronal growth and apoptosis....

  8. Analýza tréninku snowboardcrossové reprezentace České republiky

    OpenAIRE

    Řehák, Tomáš

    2012-01-01

    Title: Analysis of training program in the Czech snowboardcross representation Objectives: The main objective of this thesis is to describe an annual training cycle of the Czech snowboardcross representation. Sub-objective is to analyze the individual periods of characteristic sport's preparation. Methods: In our work we used the method of involved observation, analysis, survey, interview with the instructions and informal interview. During the observation of competitor's behavior in their tr...

  9. Betydningen af ”Virtuel Genoptræning” for motivation og fastholdelse af træning

    DEFF Research Database (Denmark)

    Mogensen, Finn Riiskjær; Jakobsen, Pernille

    2016-01-01

    UC SYD har gennemført en undersøgelse af faktorer, som har betydning for fastholdelse af træningsmotivation og funktionsniveau efter endt forløb med ”Virtuel Genoptræning”. Undersøgelsen er gennemført i Esbjerg kommune med 37 ældre borgere. Data er indsamlet via strukturerede interviews med de...

  10. cluster randomIzed trIal of the uptake of a take-home Infant dose of ...

    African Journals Online (AJOL)

    2010-07-07

    Jul 7, 2010 ... cluster randomIzed trIal of the uptake of a take-home Infant dose of nevIrapIne In kenya. H. W. ReynOldS, O. GACHunO, J. kAyITA, m. A. HAyS and J. RAkWAR, abstract. Objective: to test whether a single take home dose of infant nevirapine increased infant uptake without decreasing institutional deliveries.

  11. Pérdidas laborales atribuibles a la mortalidad prematura por lesiones de tránsito entre 2002 y 2012

    Directory of Open Access Journals (Sweden)

    Patricia Cubí-Mollá

    2015-09-01

    Conclusiones: Las pérdidas laborales asociada a muertes prematuras por lesiones de tránsito disminuyeron en el periodo analizado. Pese a ello, la cifra acumulada es de una enorme magnitud. La estimación del impacto económico de los problemas de salud puede complementar a indicadores de otras dimensiones y servir de herramienta de apoyo en la planificación de políticas públicas.

  12. Mudando o debate sobre o tráfico de mulheres Shifting the debate on the traffic of women

    Directory of Open Access Journals (Sweden)

    Kamala Kempadoo

    2005-12-01

    Full Text Available Neste texto apresento perspectivas e abordagens importantes no debate internacional sobre o tráfico de pessoas, e sublinho alguns dos principais pontos de crítica sobre o referencial contemporâneo hegemônico, pontos esses articulados através de projetos de pesquisa-ação e de intervenções contra o tráfico nas bases da sociedade. Argumento que, a despeito de mudanças substanciais no entendimento global sobre o tráfico, fortemente influenciadas por dois discursos feministas claramente diferentes (feminismo radical e feminismo transnacional, muito do que se busca hoje em nome de uma guerra ao tráfico tem conseqüências problemáticas para comunidades pobres ao redor do mundo, e tem implicações em termos de raça e gênero. As políticas norte-americanas são aqui trazidas ao debate para ilustrar algumas dessas tendências.In this text I present central perspectives and approaches in the international debate about the trafficking of persons, and highlight some of the main points of critique about the contemporary hegemonic framework that are articulated through action-research projects and grassroots anti-trafficking interventions. I argue that despite substantial shifts in global understandings about trafficking, which are heavily influenced by two distinctly different feminist discourses (radical feminism and transnational feminism, today much of what is pursued in the name of a war on trafficking has troubling consequences for poor communities around the world, and has gendered and racialized implications. US anti-trafficking policies are drawn upon here to illustrate some of these tendencies.

  13. ReTrOS: a MATLAB toolbox for reconstructing transcriptional activity from gene and protein expression data.

    Science.gov (United States)

    Minas, Giorgos; Momiji, Hiroshi; Jenkins, Dafyd J; Costa, Maria J; Rand, David A; Finkenstädt, Bärbel

    2017-06-26

    Given the development of high-throughput experimental techniques, an increasing number of whole genome transcription profiling time series data sets, with good temporal resolution, are becoming available to researchers. The ReTrOS toolbox (Reconstructing Transcription Open Software) provides MATLAB-based implementations of two related methods, namely ReTrOS-Smooth and ReTrOS-Switch, for reconstructing the temporal transcriptional activity profile of a gene from given mRNA expression time series or protein reporter time series. The methods are based on fitting a differential equation model incorporating the processes of transcription, translation and degradation. The toolbox provides a framework for model fitting along with statistical analyses of the model with a graphical interface and model visualisation. We highlight several applications of the toolbox, including the reconstruction of the temporal cascade of transcriptional activity inferred from mRNA expression data and protein reporter data in the core circadian clock in Arabidopsis thaliana, and how such reconstructed transcription profiles can be used to study the effects of different cell lines and conditions. The ReTrOS toolbox allows users to analyse gene and/or protein expression time series where, with appropriate formulation of prior information about a minimum of kinetic parameters, in particular rates of degradation, users are able to infer timings of changes in transcriptional activity. Data from any organism and obtained from a range of technologies can be used as input due to the flexible and generic nature of the model and implementation. The output from this software provides a useful analysis of time series data and can be incorporated into further modelling approaches or in hypothesis generation.

  14. Ana Vaz Milheiro, Nos Trópicos Sem Le Corbusier: Arquitectura Luso-africana no Estado Novo

    OpenAIRE

    Agarez, Ricardo

    2013-01-01

    Nos Trópicos Sem Le Corbusier: Arquitectura Luso-africana no Estado Novo examines the circulation of architectural cultures and actors in and between the historically-related contexts of Portugal, Brazil and the former Portuguese colonies in Africa, during the first three quarters of the twentieth century. This generously illustrated, Portuguese-language volume is a collection of ten essays written by Ana Vaz Milheiro between 2006 and 2011, and previously published either in the proceedings o...

  15. TR-PIV measurement of the wake behind a grooved cylinder at low Reynolds number

    Science.gov (United States)

    Liu, Ying Zheng; Shi, Liu Liu; Yu, Jun

    2011-04-01

    A comparative study of the wakes behind cylinders with grooved and smooth surfaces was performed with a view to understand the wake characteristics associated with the adult Saguaro cacti. A low-speed recirculation water channel was established for the experiment; the Reynolds number, based on the free-stream velocity and cylinder diameter (D), was kept at ReD=1500. State-of-the-art time-resolved particle image velocimetry (TR-PIV) was employed to measure a total of 20 480 realizations of the wake field at a frame rate of 250 Hz, enabling a comprehensive view of the time- and phase-averaged wake pattern. In comparison to the wake behind the smooth cylinder, the length of the recirculation zone behind the grooved cylinder was extended by nearly 18.2%, yet the longitudinal velocity fluctuation intensity was considerably weakened. A global view of the peaked spectrum of the longitudinal velocity component revealed that the intermediate region for the grooved cylinder, which approximately corresponds to the transition region where the shear layer vortices interact, merge and shed before the formation of the Karman-like vortex street, was much wider than that for the smooth one. The unsteady events near St=0.3-0.4 were detected in the intermediate region behind the grooved cylinder, but no such events were found in the smooth cylinder system. Although the formation of the Karman-like vortex street was delayed by about 0.6D downstream for the grooved cylinder, no prominent difference in the vortex street region was found in the far wake for both cylinders. The Proper Orthogonal Decomposition (POD) method was used extensively to decompose the vector and swirling strength fields, which gave a close-up view of the vortices in the near wake. The first two POD modes of the swirling strength clarified the spatio-temporal characteristics of the shear layer vortices behind the grooved cylinder. The small-scale vortices superimposed on the shear layers behind the grooved cylinder

  16. Mortalidade masculina em três capitais brasileiras, 1979 a 2007

    Directory of Open Access Journals (Sweden)

    Carolina Terra de Moraes Luizaga

    2013-03-01

    Full Text Available INTRODUÇÃO: No Brasil, verifica-se maior mortalidade masculina em praticamente todas as idades e na quase totalidade das causas. OBJETIVO: Estimar e descrever a tendência da mortalidade masculina, entre 1979 e 2007, em São Paulo (SP, Rio de Janeiro (RJ e Porto Alegre (RS. MATERIAL E MÉTODO: As populações de estudo referem-se aos residentes nas três capitais, nos triênios 1979/81, 1990/92, 1999/2001 e 2005/07 e respectivos óbitos. As fontes de dados incluíram Instituto Brasileiro de Geografia e Estatística e Sistemas de Informações em Saúde do Brasil. Calcularam-se os coeficientes de mortalidade gerais e específicos (brutos e padronizados. RESULTADOS: Verificaram-se declínio da proporção de crianças e de jovens e crescimento da proporção de idosos. Até 24 anos, os homens predominaram na população; a partir daí observaram-se maiores participações femininas e razões de sexos cada vez mais baixas, evidenciando, entre idosos, maior presença de mulheres, fato associado à elevada mortalidade masculina. Houve perda intensa de jovens por causas externas. Em 2005/07, este grupo correspondeu à principal causa de morte masculina até a faixa de 40-44 anos. Nos grupos etários seguintes, as doenças circulatórias foram a principal causa. CONSIDERAÇÕES FINAIS: As localidades evidenciam características de cidades em desenvolvimento, com redução da fecundidade, aumento da sobrevivência e envelhecimento populacional. As estimativas do elevado risco de morrer dos homens tornam clara sua vulnerabilidade, demandando ações que possibilitem redução da mortalidade por causas evitáveis, eliminando comportamentos de risco e incentivando hábitos saudáveis. Só assim haverá aumento da esperança de vida e redução das diferenças entre as mortalidades feminina e masculina.

  17. Otite externa maligna por Pseudomonas aeruginosa: relato de três casos

    Directory of Open Access Journals (Sweden)

    Jorge El-Kadum Noujaim

    1985-12-01

    Full Text Available Os autores apresentam três pacientes, de mais de 60 anos de idade, diabéticos de longa data, que tiveram achados clínicos, otológicos, do sistema nervoso e microbiológicos da otite externa maligna por Pseudomonas aeruginosa. O primeiro paciente, mulher de 62 anos de idade, teve na evolução clínica do processo importantes alterações de sistema nervoso, tais como meningite, de cujo LCR foi cultivada Pseudomonas aeruginosa, e envolvimento do 6º, 7º, 8º, 9º e 10º pares cranianos esquerdos; a despeito da alta mortalidade reportada nos casos com essas características, a paciente sobreviveu. O segundo enfermo, que tinha 64 anos e era do sexo masculino, teve também as queixas clássicas da condição caracterizadas por dor de ouvido intensa e persistente, saída de secreção pelo conduto auditivo e tumoração que aflorava pelo meato auditivo externo; recebeu, com bons resultados, tratamento cirúrgico aliado a esquema terapêutico antimicrobiano não realizado por tempo necessário devido à alta hospitalar solicitada pelo paciente; reinternado, já com manifestações de âmbito neurológico (paralisia do reto externo direito, evoluiu em poucos dias para a morte. O terceiro, de 70 anos de idade, também do sexo masculino, iniciou as queixas clínicas após a penetração de uma mariposa no canal auditivo externo e, apesar da presença de distúrbios do sistema nervoso (paralisia facial e torpor, sobreviveu mediante antibioticoterapia (carbenicilina + amicacina por tempo prolongado. Após revisão da literatura sobre a patologia em apreço, são feitas considerações gerais concernentes à sua patogenia, alterações clínicas, diagnóstico, terapêutica e prognóstico.

  18. Tröger’s Base Ladder Polymer for Membrane-Based Hydrocarbon Separation

    KAUST Repository

    Alhazmi, Abdulrahman

    2017-05-01

    The use of polymeric membranes for natural gas separation has rapidly increased during the past three decades, particularly for carbon dioxide separation from natural gas. Another valuable application is the separation of heavy hydrocarbons from methane (fuel gas conditioning), more importantly for remote area and off-shore applications. A new potential polymeric membrane that might be utilized for natural gas separations is a Tröger’s base ladder polymer (PIM-Trip-TB-2). This glassy polymeric membrane was synthesized by the polymerization reaction of 9, 10-dimethyl-2,6 (7) diaminotriptycene with dimethoxymethane. In this research, the polymer was selected due to its high surface area and highly interconnected microporous structure. Sorption isotherms of nitrogen (N2), oxygen (O¬2), methane (CH4), carbon dioxide (CO2), ethane (C2H6), propane (C3H8), and n-butane (n-C4H10) were measured at 35 °C over a range of pressures using a Hiden Intelligent Gravimetric Analyzer, IGA. The more condensable gases (C2H6, CO2, C3H8, and n-C4H10) showed high solubility due to their high affinity to the polymer matrix. The permeation coefficients were determined for various gases at 35 °C and pressure difference of 5 bar via the constant-pressure/variable-volume method. The PIM-Trip-TB-2 film exhibited high performance for several high-impact applications, such as O2/N2, H2/N2 and H2/CH4. Also, physical aging for several gases was examined by measuring the permeability coefficients at different periods of time. Moreover, a series of mixed-gas permeation tests was performed using 2 vol.% n-C4H10/98 vol.% CH4 and the results showed similar transport characteristics to other microporous polymers with pores of less than 2 nm. The work performed in this research suggested that PIM-Trip-TB-2 is suitable for the separation of: (i) higher hydrocarbons from methane and (ii) small, non-condensable gases such as O2/N2 and H2/CH4.

  19. A mobilidade humana na tríplice fronteira: Peru, Brasil e Colômbia

    Directory of Open Access Journals (Sweden)

    Márcia Maria de Oliveira

    2006-08-01

    Full Text Available OS MOVIMENTOS migratórios nas fronteiras amazônicas ainda são pouco abordados, tanto pela academia quanto pelas instituições que lidam com a temática da mi-gração. Há elementos novos que configuram características peculiares à mobilidade humana na tríplice fronteira Peru-Colômbia-Brasil que merecem uma abordagem mais profunda do ponto de vista dos estudos migratórios. Atualmente, há fluxos conside-ráveis de migração internacional nessa região adentrando na fronteira brasileira, desafiando o Estado brasileiro a implementar uma política migratória que consiga lidar com fenômenos, tais como a presença de peruanos em situação irregular em território brasileiro, a mobilidade dos povos indígenas nas regiões de fronteira e ainda, mais recentemente, a entrada crescente de colombianos desplazados pela guerrilha interna que pedem refúgio ao Estado brasileiro.THE MIGRATORY mobility in the Amazonian borders is less than enough investigated, neither by the academy nor by the institutions that deal with the migration question. There are new elements that depict peculiar characteristics to the human mobility in the triple border of Peru, Colombia and Brazil, that deserve a deeper investigation from the view point of the migratory studies. At the moment, it has conside-rable flows of international migration in this region moving in the Brazilian border, challenging the Brazilian State to implement a migratory policy that is able to deal with the phenomena such as the presence of Peruvians in an irregular situation in Brazilian territory, the mobility of the indigenous peoples in the border regions and still, more recently, the increasing entrance of the Colombians desplazados through the internal guerrilla who ask for shelter to the Brazilian State.

  20. [Clinical usefulness of IDEA and CARS: concordance with DSM-IV-TR in children and adolescents with suspicion of PDD].

    Science.gov (United States)

    García-López, C; Narbona, J

    2014-02-01

    Observational scales are useful to estimate the severity of symptoms in PDD as well as to monitor their evolution. a) To analyze the concordance between diagnoses based on the Autism Spectrum Inventory (Inventario del Espectro Autista, IDEA)) and the Childhood Autism Rating Scale (CARS), compared to DSM-IV-TR criteria, in subjects with a suspicion of pervasive developmental disorders (PDD), and b) to study the discrimination power of both scales to differentiate between a clinical diagnosis situated in the autism spectrum. Fifty-six children and adolescents, between 2 and 20 years-old, who attended our Neuropediatric Unit due to suspicion of PDD. Independently, two clinicians evaluated the presence of PDD symptoms; one of them according to DSM-IV-TR criteria and the other one based on the application of IDEA and CARS. The concordance of IDEA and CARS when compared to DSM-IV-TR classification was 73 and 82%, respectively, with a sensitivity of 1 and 0,83 and a specificity of 0,61 and 0,82, respectively. Both scales correctly discriminated between autistic disorder and other clinical diagnoses. Both IDEA and CARS are useful instruments to detect and monitor autism symptoms in the context of routine clinical practice. Copyright © 2012 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.

  1. Recursos disponibles para la protección de mujeres migrantes en tránsito por Tamaulipas

    Directory of Open Access Journals (Sweden)

    Rocío CÁRDENAS-RODRÍGUEZ

    2014-01-01

    Full Text Available La labor del gobierno mexicano en materia de política migratoria es una estrategia para administrar el flujo de migrantes en tránsito rumbo a Estados Unidos, no para salvaguardar su integridad y derechos, menos aún está diseñada para proteger a las mujeres. En esa medida, el interés de este artículo es hacer evidentes los escasos recursos de protección disponibles para migrantes y la ausencia de perspectiva de género en los recursos de apoyo para mujeres en tránsito por México. A través de entrevistas a autoridades y organismos sociales en la frontera de Tamaulipas y con base en el enfoque del modelo ecológico, se evaluaron los recursos de la política pública mexicana como elementos amortiguadores para los migrantes, frente a riesgos y elementos de vulnerabilidad de la mujer en tránsito.

  2. Análise do desempenho do basquetebol brasileiro ao longo de três temporadas do Novo Basquete Brasil

    Directory of Open Access Journals (Sweden)

    Lucas Rodrigues Meneses

    2016-03-01

    Full Text Available Resumo O estudo verificou a evolução do basquetebol brasileiro a partir dos índices de desempenho (ID das equipes em três temporadas do Novo Basquete Brasil (2009 a 2012 e determinou valores de referência (percentis dos principais ID. Os dados foram coletados no site da Liga Nacional de Basquete. Foram analisados em 726 jogos os ID mais frequentes na análise do jogo de basquetebol pela ANOVA de um fator (post hoc de Tukey. A temporada 2011/12 apresentou menor número de arremessos de três pontos e maior de dois pontos, melhor aproveitamento nos lances livres e redução nos rebotes ofensivos. Os percentis indicam alto grau de exigência para a performance das equipes nos ID analisados. Nota-se uma tendência à modificação do estilo de jogo das equipes ao longo das três temporadas.

  3. Helena de Eurípides: entre lo cómico y lo trágico

    Directory of Open Access Journals (Sweden)

    Álvaro Sáenz Alfonso

    2017-07-01

    Full Text Available Tanto los críticos antiguos como los románticos alemanes y varios académicos de los últimos dos siglos han identificado ciertas características de la obra de Eurípides que luego pasaron a ser esenciales del género cómico. Helena es una de las tragedias que citan recurrentemente estos críticos que defienden la idea anterior, lo que ha llevado a pensar que esta obra no encaja realmente en el género trágico. Mi intención es resaltar el carácter trágico de Helena por medio de una comparación con Medea. Para lograr esto ofrezco un criterio de identificación de lo trágico en Eurípides. Ancient critics, as well as the German romantics and several scholars from the past two centuries, have identified certain characteristic in Euripides’s work that later became essential to the comic genre. Helen is one of the tragedies that this critics frequently cite in order to defend this position, and this has led to the idea that the work does not really fit within the tragic genre. My intention is to highlight the tragic character of Helen by means of a comparison with Medea. In order to accomplish this, I offer some criteria for classifying what is to be considered tragic in Euripides’s work.

  4. Identification of Large Scale Structures in the Wake of Cavitating Hydrofoils Using LES and TR-PIV

    Science.gov (United States)

    Wosnik, Martin

    2005-11-01

    Large-scale three-dimensional cavitating structures exist in the wake of two-dimensional hydrofoils, as a result of sheet/cloud cavitation. This type of cavitation produces unsteady lift on most hydrofoils -- including the NACA 0015 studied here -- but is sufficiently periodic to have potential for control. A Large Eddy Simulation (LES) based on a virtual single-phase, fully compressible cavitation model captures the complex dynamical features of this highly unsteady cavitating flow well. The LES results are compared to Time-Resolved Particle Image Velocimetry (TR-PIV, recorded at 2000Hz) in the region immediately downstream of the hydrofoil, with particular attention to the predicted vortex shedding mechanisms. With a careful choice of photometric parameters and adaptive masking, the large, vortical, cavitating structures are identified quantitatively. The existence of the primary vortex pair predicted by the LES is confirmed by TR-PIV. This vortex pair produces large cross-stream velocities, with a general ejection direction of 3/4 π to the free stream. However, the shedding pattern as recorded with TR-PIV is not nearly as regular as in the LES, due to the limited number of spanwise grid points in the simulation and the highly three- dimensional nature of cloud cavitation shedding in the experiment.

  5. Control y simulación de tráfico urbano en Colombia: Estado del arte

    Directory of Open Access Journals (Sweden)

    Daniel Robles

    2009-05-01

    Full Text Available Las condiciones actuales de la movilidad en Colombia generan interrogantes acerca de qué tan apropiadas son las estrategias de control de tráfico aplicadas en las redes urbanas del país. Con esto en mente, se plantea una revisión de las estrategias de control y plataformas de simulación de sistemas de tráfico más utilizadas en Colombia y en otras partes del mundo; con el propósito de caracterizar el nivel de desarrollo del país en el estudio e implementación de estrategias de control de tráfico urbano y, posteriormente, formular propuestas orientadas hacia la mejora de la movilidad urbana en el país./ The current mobility conditions in Colombia give place to questions about the suitability of the traffic control strategies applied on the Colombian urban networks. Therefore, a review of the control strategies and simulation platforms used in Colombia and around the world is shown. This is done to characterize the level of development of the country, in terms of research and implementation of such control strategies and, furthermore, to formulate proposals oriented towards the improvement of the Colombian urban mobility.

  6. Neurocriptococose na infância: relato de três casos na primeira década de vida

    Directory of Open Access Journals (Sweden)

    Maria Helena Fontana

    1987-12-01

    Full Text Available Os autores relatam três casos de neurocriptococose em crianças na primeira década de vida, no Estado do Rio Grande do Sul. O diagnóstico foi estabelecido pelo encontro do fungo Cryptococcus neoformans no líquido céfalo-raquidlano por exame direto com tinta da China e cultura em meio de Sabouraud. As formas de instalação da síndrome neurológica foram aguda, subaguda e crônica. Síndrome de hipertensão intracraniana e hidrocefalia foram complicações observadas durante a evolução da doença, sendo necessária a instalação de derivação ventrículo-peritonial em um caso. Desnutrição foi o processo mórbido associado nos três casos e infecção pelo bacilo da tuberculose em um caso. Terapia específica foi administrada aos três pacientes. Um paciente evoluiu para cura e dois evoluíram para óbito.

  7. Adquisición de variables de tráfico vehicular usando visión por computador

    Directory of Open Access Journals (Sweden)

    Germán Enrique Urrego

    2009-11-01

    Full Text Available El conteo de vehículos es una tarea fundamental en los aforos de tráfico, tanto para el diseño de nuevas vías como para el control y la optimización del tráfico urbano. En ciudades como Bogotá, este conteo actualmente se realiza en forma manual, pero puede hacerse automáticamente empleando técnicas de visión por computador. El presente artículo muestra el desarrollo de un algoritmo de detección y seguimiento de vehículos en tiempo real a partir de video, el cual permite el conteo de vehículos en la vía y la estimación del volumen de tráfico o velocidad promedio./The count of vehicles is a key task in traffic gauging, as it provides information for designing new roads, and for the control and optimization of urban traffic. Nowadays in cities like Bogota, vehicle counting is done manually, but it can also be done automatically using computer vision techniques. This article presents the development of an algorithm for detecting and tracking vehicles in real time from video. The algorithm allows to count vehicles on the road and to estimate traffic volume or average speed.

  8. Três análises de linguagem no autismo Three language analysis in autism

    Directory of Open Access Journals (Sweden)

    Michele Paula Moro

    2011-10-01

    Full Text Available TEMA: Linguagem no Autismo. OBJETIVOS: analisar, comparativamente, dados de linguagem obtidos por meio de dois protocolos, um da interação mãe-criança e outro de atos comunicativos da criança entre si e com a análise dialógica da díade mãe-filho. Outro objetivo foi discutir as implicações de tais análises para o planejamento terapêutico. MÉTODO: a amostra constou de três sujeitos na faixa etária de 2 anos e 1 mês a 4 anos e 6 meses, com diagnóstico de distúrbio de linguagem secundário ao espectro autístico. A coleta foi realizada por meio da filmagem de sessões de interação lúdica, de 30 minutos, dos sujeitos com suas mães. Os procedimentos de análise foram: a transcrição das filmagens, conferência das mesmas, aplicação de dois protocolos, um de análise da interação mãe-filho e outro de comportamentos comunicativos da criança, e uma análise qualitativa da atividade dialógica da díade. RESULTADOS: Os resultados do protocolo de interação mãe-filho demonstraram freqüência similar de categorias dos comportamentos das três mães, com elevado número de perguntas e de diretividade intrusiva. No mesmo protocolo, as crianças demonstraram brincar exploratório e funcional, estereotipias verbais e não verbais, fato também observado no protocolo de pragmática. O protocolo de interação permite observar melhor que os comportamentos infantis e maternos possuem relações, mas apenas a análise qualitativa possibilita identificar a natureza dialética de tais relações. CONCLUSÃO: O protocolo que analisa a interação provê informações fundamentais ao planejamento terapêutico, adicionais ao protocolo de foco exclusivo no conhecimento pragmático do sujeito. Aquele protocolo, em conjunto com a análise qualitativa, permite uma seleção mais qualificada das estratégias de intervenção em cada caso.BACKGROUND: Language in autism. PURPOSE: the data obtained through two protocols and also from the

  9. A model-based assessment of the TrOCA approach for estimating anthropogenic carbon in the ocean

    Directory of Open Access Journals (Sweden)

    A. Yool

    2010-02-01

    Full Text Available The quantification of the amount of anthropogenic carbon (Cant that the ocean has taken up from the atmosphere since pre-industrial times is a challenging task because of the need to deconvolute this signal from the natural, unperturbed concentration of dissolved inorganic carbon (DIC. Nonetheless, a range of techniques have been devised that perform this separation using the information implicit in other physical, biogeochemical, and man-made ocean tracers. One such method is the TrOCA approach, which belongs to a group of back-calculation techniques, but relative to other methods employs a simple parameterization for estimating the preformed, pre-industrial concentration, the key quantity needed to determine Cant. Here we examine the theoretical foundation of the TrOCA approach and test its accuracy by deconvoluting the known distribution of Cant from an ocean general circulation model (OGCM simulation of the industrial period (1864–2004. We reveal that the TrOCA tracer reflects the air-sea exchange of both natural and anthropogenic CO2 as well as that of O2. Consequently, the determination of the anthropogenic CO2 flux component requires an accurate determination not only of the contribution of the natural (pre-industrial CO2 flux component, but also of the O2 flux component. The TrOCA method attempts to achieve this by assuming that the concentration changes invoked by these two air-sea flux components scale with temperature and alkalinity. While observations support a strong exponential scaling of the oxygen flux component with temperature, there exists no simple relationship of the natural CO2 flux component with temperature and/or alkalinity. This raises doubts whether the sum of these two components can be adequately parameterized with a single function. The analyses of the model support this conclusion, even when Cant is

  10. Tríplice artrodese na paralisia cerebral Triple arthrodesis in cerebral palsy

    Directory of Open Access Journals (Sweden)

    Kotoe Umeda

    2010-01-01

    Full Text Available OBJETIVOS: Avaliar o resultados clínicos díplice artrodese em portadores de paralisia cerebral espástica, verificar a correspondência entre os resultados e a escala AOFAS e os ângulos nos períodos pré e pós-operatórios. MÉTODOS: Entre 1985 e 2005, foram avaliados 34 pacientes (40 pés submetidos a tríplice artrodese do pé, com acompanhamento médio de 91 meses, quanto a satisfação e dor, apoio plantígrado, deformidade residual e o arco de movimento do tornozelo e escala AOFAS. Foram avaliadas artrose de tornozelo, pseudoartrose das articulações e medidos os ângulos: talocalcâneo, talo-primeiro metatarsiano (APM e tíbio-talar, e talocalcâneos (ATC e o calcâneo-solo (ACS. RESULTADOS: Obtivemos bons resultados em 32,4% dos casos e regulares em 44,1%. 85,3% dos pacientes estavam satisfeitos; 88,2% tinham apoio plantígrado. Houve 33,3% de resultados bons pela escala AOFAS e 24,2% regulares. Na radiografia com incidência ântero-posterior, o APM apresentou melhora em média de 15º; no ACS, na incidência em perfil, melhora de 7º. No ATC, nas duas incidências, houve melhora de 1º. CONCLUSÕES: A triplice artrodese corrige ou melhora as deformidades, com grau de satisfação elevada, dando ao paciente pés plantígrados. A escala AOFAS teve fraca concordância com o resultado. Os APM e ACS foram os mais sensíveis na avaliação do procedimento cirúrgico.OBJECTIVE: To demonstrate the clinical results of triple arthrodesis in Cerebral Palsy patients and determine whether there is any correspondence between the results and the AOFAS scale, and changes in radiographic angles between the pre- and postoperative periods. METHODS: Between 1985 and 2005, thirty-four patients (40 feet were submitted to triple arthrodesis of the foot, with an average follow-up time of ninety-one months. The evaluation consisted of the patient's satisfaction and the presence of pain, plantigrade support, residual deformity, range of movement of the

  11. Antecedentes y perspectivas de la actividad bufalina en el trópico

    Directory of Open Access Journals (Sweden)

    Alina Mitat Valdés

    2011-11-01

    y para que los gobiernos se involucren en programas que posibiliten, a partir de esta especie, contribuir a mitigar la pobreza y el desarrollo rural local.En este artículo se expresarán algunas consideraciones sobre los antecedentes y perspectivas de la crianza de los búfalos de agua en el trópico, para poder discutiraciertos y desaciertos, así como encontrar las mejores alternativas que nos permitan obtener, altos resultados productivos sin dañar el entorno, logrando incrementar los conocimientos sobre la especie y la coordinación entre las instituciones responsabilizadas con el trabajo en el ecosistema centroamericano.

  12. Trata de seres humanos y tráfico de inmigrantes en los albores del siglo XXI (Artículos Varios)

    OpenAIRE

    Storini, Claudia

    2006-01-01

    Esta investigación analiza con detalle la evolución conceptual y la heterogeneidad de definiciones entre dos tipos principales de tráfico de personas, esto es, la trata para la explotación de seres humanos y el tráfico de migrantes. Conjuntamente se estudia el desarrollo de la cooperación internacional de la acción supranacional y nacional en materia de lucha contra el tráfico de personas, se describen los aspectos más significativos y se analizan los obstáculos que la limitan o frenan, con e...

  13. Estudo comparativo de três projetos de restauração de áreas degradadas de manguezais da grande Florianópolis, SC

    OpenAIRE

    Huber, Marlí Velasques

    2004-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-graduação em Engenharia Ambiental. Estudo comparativo de três projetos de recuperação em áreas de manguezais da Baia Norte, região da Grande Florianópolis, Santa Catarina, Brasil.O objetivo deste estudo foi comparar três projetos de restauração com plantio de mangues das três espécies típicas Avicennia schaueriana, Laguncularia racemosa e Rhizophora mangle, em áreas degradadas de manguezais...

  14. Desarrollo de un modelo dinámico de tráfico multimodal (automóviles, articulados, peatones y bicicletas) con fines de control

    OpenAIRE

    Portilla Caicedo, Christian Roviro

    2015-01-01

    En esta tesis se describe un modelo macroscópico de tráfico vehicular y se proponen tres nuevos modelos para el tráfico de buses articulados, bicicletas y peatones, con el fin de explicar dinámicamente el comportamiento del tráfico multimodal urbano. Los parámetros de estos modelos fueron estimados mediante la solución de problemas de optimización, los cuales minimizan la diferencia entre los datos teóricos y los datos experimentales, adquiridos mediante la toma de datos reales para casos de ...

  15. Estructura trófica de los copépodos pelágicos en el Océano Pacifico Oriental Tropical

    OpenAIRE

    López Ibarra, Gladis Angélica

    2008-01-01

    Gran parte de la productividad secundaria marina es aportada por los copépodos, estos destacan dentro del zooplancton marino por su diversidad y abundancia, puede llegar a constituir un 80 % de la biomasa zooplanctonica. Probablemente el principal papel ecológico de esta comunidad es la transferencia de energía entre los niveles tróficos primarios y los sucesivos en las redes tróficas. En este estudio se analizó la estructura trófica de la comunidad de copépodos pelágicos en el Océano Pacifi...

  16. Análisis funcional de la red trófica de Bahía Magdalena Baja California Sur, México

    OpenAIRE

    Cruz-Escalona,Víctor H; Morales-Zárate,María V; Navia,Andrés F; Rguez-Baron,Juan M; del Monte-Luna,Pablo

    2013-01-01

    El objetivo del presente estudio fue desarrollar un modelo trófico (ECOPATH con ECOSIM) para caracterizar la estructura y función de la trama alimentaria de Bahía Magdalena. El modelo consta de 24 grupos funcionales, siendo dominado por grupos de niveles tróficos secundarios y terciarios, que generan un tercio de los flujos de biomasa total. Los flujos totales del sistema y la eficiencia de transferencia promedio entre niveles tróficos, encajan bien en el rango reportado para otros ecosistema...

  17. Copepod parasites of Curimatella lepidura (Characiformes, Curimatidae from the Três Marias Reservoir, Brazil Copépodes parasitos de Curimatella lepidura (Characiformes, Curimatidae do reservatório de Três Marias, Brasil

    Directory of Open Access Journals (Sweden)

    M.C. Albuquerque

    2008-10-01

    Full Text Available Copépodes ergasilídeos coletados nas brânquias de Curimatella lepidura do reservatório de Três Marias, alto rio São Francisco, Minas Gerais, Brasil e identificados como Miracetyma etimaruya e Ergasilus sp., constituem o primeiro registro de parasitos nesse peixe forrageiro e endêmico. A ocorrência foi independente do sexo e do tamanho dos peixes. A distribuição geográfica conhecida das espécies de Miracetyma Malta, 1993, restrita à bacia do rio Amazonas, é ampliada neste estudo para a bacia do rio São Francisco.

  18. Atributos físicos de Cambissolo Háplico em vinhedos submetidos a intensidades de tráfego

    Directory of Open Access Journals (Sweden)

    Cassio Marques de Valois

    2014-08-01

    Full Text Available Em vinhedos, o tráfego de máquinas agrícolas causa compactação do solo que pode ser mais acentuada nas entrelinhas pela maior intensidade de tráfego. Este trabalho objetivou avaliar a variabilidade dos atributos físicos do solo em razão da posição de amostragem em relação à linha de plantio, em vinhedos comerciais da variedade Bordô em pé franco, submetidos a diferentes manejos da cultura. Em fevereiro de 2012, três vinhedos foram selecionados no município de Major Gercino (SC, sendo um manejado sem a utilização de máquinas agrícolas (vinhedo 1: com seis anos de implantação e dois que utilizam máquinas nas entrelinhas (vinhedos 2 e 3: com oito e 17 anos, respectivamente. Na linha de plantio (Lp, na linha do rodado (Lr e entre a linha de plantio e a linha do rodado (El, foram coletadas amostras indeformadas de solo nas camadas de 0,00-0,05, 0,05-0,10, 0,10-0,15 e 0,15-0,20 m de profundidade. Avaliaram-se a densidade do solo (Ds, a resistência à penetração (Rp, as classes de poros (macroporos - MaP, mesoporos - MeP, microporos - MiP e porosidade total - PT, os índices de agregação e de estabilidade de agregados (Diâmetro médio geométrico dos agregados secos ao ar e estáveis em água - DMGsa e DMGea, índice de estabilidade de agregados - IEA, a umidade gravimétrica (Ug, a densidade das partículas e a granulometria do solo. O estado de compactação aumentou no sentido da Lp para a Lr. A ocorrência de tráfego, em geral, influenciou negativamente os atributos avaliados. Entre as posições de amostragem, os maiores valores de Ds e Rp ocorreram na Lr, em que a Rp atingiu valores críticos ao desenvolvimento de raízes; nos vinhedos mecanizados, foram encontrados elevados valores de Rp e baixos de MaP nas camadas de 0,00-0,05 e 0,05-0,10 m. Observaram-se agregados com maior diâmetro e menores IEA, o que indica deterioração da qualidade física do solo. No vinhedo 1, houve menor variabilidade dos atributos f

  19. Cross check of the new economic and mass balance feature of the fuel cycle scenario code TR-EVOL

    International Nuclear Information System (INIS)

    Merino-Rodriguez, I.; Garcia-Martinez, M.; Alvarez-Velarde, F.; Lopez, D.

    2016-01-01

    Versatile computational tools with up to date capabilities are needed to assess current nuclear fuel cycles or the transition from the current status of the fuel cycle to the more advanced and sustainable ones. The TR-EVOL module, that is devoted to fuel cycle mass balance, simulates diverse nuclear power plants (PWR, SFR, ADS, etc.), having possibly different types of fuels (UO 2 , MOX, etc.), and the associated fuel cycle facilities (enrichment, fuel fabrication, processing, interim storage, waste storage, geological disposal). This work is intended to cross check the new capabilities of the fuel cycle scenario code TR-EVOL.This process has been divided in 2 stages. The first stage is dedicated to check the improvements in the nuclear fuel mass balance estimation using the available data for the Spanish nuclear fuel cycle. The second stage has been focused in verifying the validity of the TR-EVOL economic module, comparing results to data published by the ARCAS EU project. A specific analysis was required to evaluate the back-end cost. Data published by the waste management responsible institutions was used for the validation of the methodology. Results were highly satisfactory for both stages. In particular, the economic assessment provides a difference smaller than 3% regarding results published by the ARCAS project (NRG estimations). Furthermore, concerning the back-end cost, results are highly acceptable (7% difference for a final disposal in a once-through scenario and around 11% for a final disposal in a reprocessing strategy) given the significant uncertainties involved in design concepts and related unit costs. (authors)

  20. Bacterially activated B-cells drive T cell differentiation towards Tr1 through PD-1/PD-L1 expression.

    Science.gov (United States)

    Said, Sawsan Sudqi; Barut, Guliz Tuba; Mansur, Nesteren; Korkmaz, Asli; Sayi-Yazgan, Ayca

    2018-04-01

    Regulatory B cells (Bregs) play a crucial role in immunological tolerance primarily through the production of IL-10 in many diseases including autoimmune disorders, allergy, infectious diseases, and cancer. To date, various Breg subsets with overlapping phenotypes have been identified. However, the roles of Bregs in Helicobacter infection are largely unknown. In the present study, we investigate the phenotype and function of Helicobacter -stimulated B cells. Our results demonstrate that Helicobacter felis -stimulated IL-10- producing B cells (Hf stim - IL-10 + B) are composed of B10 and Transitional 2 Marginal Zone Precursor (T2-MZP) cells with expression of CD9, Tim-1, and programmed death 1 (PD-1). On the other hand, Helicobacter felis -stimulated IL-10- nonproducing B (Hf stim - IL-10 - B) cells are mainly marginal zone (MZ) B cells that express PD-L1 and secrete TGF-β, IL-6, and TNF-α, and IgM and IgG2b. Furthermore, we show that both Hf stim - IL-10 + B cells and Hf stim - IL-10 - B cells induce CD49b + LAG-3 + Tr1 cells. Here, we describe a novel mechanism for PD-1/PD-L1- driven B cell-dependent Tr1 cell differentiation. Finally, we explore the capability of Hf stim - IL-10 - B cells to induce Th17 cell differentiation, which we find to be dependent on TGF-β. Taken together, the current study demonstrates that Hf stim - B cells induce Tr1 cells through the PD-1/PD-L1 axis and Th17 cells by secreting TGF-β. Copyright © 2018 Elsevier Ltd. All rights reserved.

  1. Variações experimentais: um estudo sobre a narrativa em A trégua, de Primo Levi

    Directory of Open Access Journals (Sweden)

    Pedro Caldas

    2016-02-01

    Full Text Available Este artigo pretende contribuir com a discussão sobre a narrativa a partir de uma leitura de A trégua, de Primo Levi. Publicado em 1963, A trégua é o segundo livro de Primo Levi, concluído dezesseis anos após É isto um homem?, e traz uma questão inquietante: por um lado, o livro, ao contar a história do retorno de Primo Levi para sua casa, em Turim, após ser libertado do campo de concentração de Auschwitz, é também uma narrativa de reencontro com a própria humanidade; por outro lado, o autor, no final, admite sua angústia ao reconhecer que o mal de Auschwitz permanecerá para sempre com ele. Portanto, o que muda? Como contar uma narrativa que não elabora uma mudança essencial, mas episódios possivelmente aleatórios? Neste sentido, proponho o conceito de uma narrativa estruturada a partir de “variações experimentais” em torno à experiência de trégua. Formulação retirada de uma das mais marcantes caracterizações do livro, o menino Hurbinek, em cujo nome Levi testemunha, as “variações experimentais” podem ser compreendidas como uma alternativa ao impasse acima entre episódios expressivos e sua relativa incapacidade de gerar alguma mudança significativa no sentido histórico do Holocausto.

  2. A inaplicabilidade da advertência escrita nas sanções de trânsito

    Directory of Open Access Journals (Sweden)

    Daniel Angelo Passaia

    2017-07-01

    Full Text Available O presente artigo tem como escopo o direito de trânsito brasileiro, área não esmiuçada com a profundeza que merece, notadamente quando se trata da jurisprudência e doutrina especializada. O estudo é relacionado diretamente às sanções previstas nas normatizações do direito de trânsito – Lei 9.503/97 – e, nesta conjectura, pontualmente atinente a substituição da multa pecuniária pela advertência por escrito, cuja estipulação histórica e social, distingue-se amplamente das atuais finalidades. O texto legal é do art. 267 da lei retro citada, conhecida como Código de Trânsito Brasileiro. A problemática, portanto, reside na inaplicabilidade da advertência por escrito, mesmo diante da previsão legal. Hipoteticamente verifica-se afronta à esfera jurídica do indivíduo que sofre aplicação de sanções de natureza leve ou média. O estudo tem por método o qualitativo e como técnicas utiliza-se da análise bibliográfica e documental. A consulta à jurisprudência demonstrou inexistirem resultados contemplando esta discussão em específico, enquanto a doutrina impõe algumas exigências que não se vislumbram na legislação, o que, fez incontroversa, ao menos neste tempo e espaço, a hipótese lançada inicialmente. O estudo atinge diretamente os direitos sociais dos indivíduos, dirigindo-se não somente ao objeto em exame, mas, como toda pesquisa, para os sujeitos.

  3. Estudo da atividade do látex do Croton urucurana Baill. sobre o trânsito gastrintestinal de camundongos

    Directory of Open Access Journals (Sweden)

    Luilma Albuquerque Gurgel

    Full Text Available O presente trabalho tem como propósito avaliar uma possível atividade inibitória do látex do Croton urucurana Baill. sobre o trânsito gastrintestinal de camundongos, bem como tentar esclarecer os possíveis mecanismos de ação envolvidos em sua atividade. Foram utilizados os modelos de trânsito gastrintestinal normal e trânsito gastrintestinal estimulado por fisostigmina em camundongos. Os resultados obtidos mostram que o látex inibiu o trânsito gastrintestinal de camundongos, e, muito embora seu mecanismo de ação ainda não seja claro, seu efeito é independente da participação de mecanismo opióide, colinérgico, α2-adrenérgico ou nitriérgico.

  4. Ferroelectric coupling effect on the energy-band structure of hybrid heterojunctions with self-organized P(VDF-TrFE) nanomatrices.

    Science.gov (United States)

    Shin, Kyung-Sik; Kim, Tae Yun; Yoon, Gyu Cheol; Gupta, Manoj Kumar; Kim, Sung Kyun; Seung, Wanchul; Kim, Hyeok; Kim, Sungjin; Kim, SeongMin; Kim, Sang-Woo

    2014-08-27

    Ferroelectric coupling effects on the energy-band structure of hybrid heterojunctions are investigated using hybrid photovoltaic devices with poly(3-hexylthiophene-2,5-diyl) (P3HT)/ZnO and poly(vinylidene fluoride-trifluoroethylene) (P(VDF-TrFE)). The self-organized P(VDF-TrFE):P3HT photoactive layer forms a novel architecture consisting of P3HT domains in a P(VDF-TrFE) matrix. The energy-band structure at the interface of the p-n heterojunction is tuned by artificial control of the ferroelectric polarization of the P(VDF-TrFE) material, consequently modulating the photovoltaic performance of the hybrid photovoltaic devices. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. One-pot facile synthesis of 4-amino-1,8-naphthalimide derived Tröger's bases via a nucleophilic displacement approach.

    Science.gov (United States)

    Shanmugaraju, Sankarasekaran; McAdams, Deirdre; Pancotti, Francesca; Hawes, Chris S; Veale, Emma B; Kitchen, Jonathan A; Gunnlaugsson, Thorfinnur

    2017-09-13

    We report here a novel one-pot synthetic strategy for the synthesis of a family of N-alkyl-1,8-naphthalimide based Tröger's bases via a nucleophilic substitution reaction of a common 'precursor' (or a 'synthon') N-aryl-1,8-naphthalimide Tröger's base heated at 80 °C in neat aliphatic primary amine, in overall yield of 65-96%. This methodology provides an efficient and one-step facile route to design 1,8-naphthalimide derived Tröger's base structures in analytically pure form without the use of column chromatography purification, that can be used in medicinal chemistry and as supramolecular scaffolds. We also report the formation of the corresponding anhydride, and the crystallographic analysis of two of the resulting products, that of the N-phenyl-4-amino-1,8-naphthalimide and the anhydride derived Tröger's bases.

  6. Supramolecular coordination polymers using a close to 'V-shaped' fluorescent 4-amino-1,8-naphthalimide Tröger's base scaffold.

    Science.gov (United States)

    Shanmugaraju, Sankarasekaran; Hawes, Chris S; Savyasachi, Aramballi J; Blasco, Salvador; Kitchen, Jonathan A; Gunnlaugsson, Thorfinnur

    2017-11-21

    A V-shaped 4-amino-1,8-naphthalimide derived dipyridyl ligand comprising the Tröger's base structural motif has been synthesised and subsequently used in the formation of two new supramolecular coordination polymers.

  7. Investigation of P(VDF-TrFE)/ZrO{sub 2}-MMA polymer composites applied to radiation shielding

    Energy Technology Data Exchange (ETDEWEB)

    Fontainha, C.C.P. [Depto. de Engenharia Nuclear - UFMG, Av. Antonio Carlos 6627, 31270-970 Belo Horizonte, MG (Brazil); Baptista Neto, A.T.; Santos, A.P.; Faria, L.O. [Centro de Desenvolvimento da Tecnologia Nuclear, Av. Antonio Carlos 6627, C.P. 941, 30270-901, Belo Horizonte, MG (Brazil)

    2015-07-01

    Exposure to high radiation dose in medical diagnostic imaging procedures can lead patients to suffer tissue damaging. However, there are several studies that identify significant dose reduction with the use of radiation protective attenuators, minimizing the delivered dose in the region that covers the main beam, while preserving the diagnostic quality of the generated image. Most radiation attenuator materials are produced from shielding metal containing composites, whose efficiency is the goal of investigations around the world. In this context, polymeric materials were chosen for this investigation in order to provide light-weighted and flexible protective composites, a must in personal protective shielding. Therefore, this work is concerned to the investigation of poly(vinylidene fluoride - try-fluor-ethylene) [P(VDF-TrFE)] copolymers mixed with zirconia nanoparticles. The resulting polymer composites, prepared with 1, 2, 3, 5 and 10 at.% of ZrO{sub 2} nanoparticles, were investigated for application as protective shielding in some interventional radiology procedures. Two variety of composites were produced, one using pure ZrO{sub 2} nanoparticles and the other using sol-gel route with zirconium butoxide as the precursor for zirconium oxide nano-clusters. The P(VDFTrFE)/ ZrO2-MMA polymer composites produced by sol-gel route have provided a much better dispersion of the pure ZrO{sub 2} material into the P(VDF-TrFE) host matrix. UV-Vis and FTIR spectrometry and differential scanning calorimetry (DSC) were used to characterize the composite samples. FTIR data reveal a possible link between the MMA monomers with the P(VDF-TrFE) chain through shared C=O bonds. The radiation shielding characterization was conducted by using a 70 kV x-rays beam which is applicable, for instances, in catheter angiography. The results demonstrate that composites with 10% of ZrO{sub 2}, and only 1.0 mm thick, can attenuate 60% of the x-rays beam. The composite density was evaluated to be

  8. Banco de sementes do solo em três fases sucessionais de uma Floresta Estacional Decidual em Santa Tereza, RS.

    OpenAIRE

    Solon Jonas Longhi; Eleandro José Brun; Diógenes Maurice Oliveira; Luis Eduardo Britto Fialho; Julio César Wojciechowski; Sandro Vaccaro

    2010-01-01

    Com o objetivo de avaliar o banco de sementes no solo e compreender aspectos da dinâmica sucessional de Floresta Estacional Decidual, foram coletadas 60 amostras de 1 m2 no final de cada estação do ano, em três estágios sucessionais (Capoeirão, Floresta Secundária e Floresta Madura). Em cada ponto amostral, foi coletado o folhedo e os primeiros 3 cm de solo. No Centro Tecnológico de Silvicultura da UFSM o material foi posto para germinar, separadamente, em canteiros de madeira de 1 m2, que co...

  9. Microrganismos endofíticos de mandioca de áreas comerciais e etnovariedades em três estados brasileiros.

    OpenAIRE

    TEIXEIRA, M. A.; MELO, I. S. de; VIEIRA, R. F.; COSTA, F. E. C.; HARAKAVA, R.

    2008-01-01

    O objetivo deste trabalho foi realizar um levantamento da diversidade de microrganismos endofíticos, em plantas de mandioca (Manihot esculenta Crantz) coletadas de áreas comerciais, no Estado de São Paulo, e de etnovariedades dos estados do Amazonas e Bahia e, também, avaliar seu potencial para fixar N atmosférico e para produzir ácido indolacético. Nos três estados, foram identificadas 47 espécies de microrganismos pertencentes a 27 gêneros. Bacillus spp. foi o mais freqüente em todas as reg...

  10. Índices de qualidade da água e de estado trófico do rio Caiabi, MT

    OpenAIRE

    Andrietti,Grasiane; Freire,Rosane; Amaral,Adriana Garcia do; Almeida,Frederico Terra de; Bongiovani,Milene Carvalho; Schneider,Roselene Maria

    2016-01-01

    Resumo Neste trabalho objetivou-se identificar a qualidade da água superficial do rio Caiabi, MT por meio do índice de qualidade de água (IQA) e índice de estado trófico (IET), bem como a avaliação das variações sazonais e espaciais, com a definição do delineamento do monitoramento mais adequado para o local de estudo. As coletas para o monitoramento da qualidade da água ocorreram em cinco pontos no rio Caiabi, entre julho de 2012 e junho de 2013. Foram quantificados os seguintes parâmetros d...

  11. A política criminal de guerra ao tráfico de drogas no Brasil

    OpenAIRE

    Oliveira, Vivian Von Hertwig Fernandes de

    2014-01-01

    Resumo: Os indivíduos imputados pela prática do crime de tráfico de drogas no Brasil, identificados em discursos autoritários como inimigos da sociedade, encontram-se submetidos a um tratamento jurídico extremamente rigoroso, marcado pela antecipação da punibilidade, cominação de penas bastante elevadas e minimização de garantias penais e processuais. Com o objetivo de demonstrar que tal tratamento jurídico pode ser considerado expressão de direito penal do inimigo, voltado à neutralização da...

  12. Transmission spectroscopy of the hot Jupiter TrES-3 b: Disproof of an overly large Rayleigh-like feature

    Science.gov (United States)

    Mackebrandt, F.; Mallonn, M.; Ohlert, J. M.; Granzer, T.; Lalitha, S.; García Muñoz, A.; Gibson, N. P.; Lee, J. W.; Sozzetti, A.; Turner, J. D.; Vaňko, M.; Strassmeier, K. G.

    2017-12-01

    Context. Transit events of extrasolar planets offer the opportunity to study the composition of their atmospheres. Previous work on transmission spectroscopy of the close-in gas giant (TrES)-3 b revealed an increase in absorption towards blue wavelengths of very large amplitude in terms of atmospheric pressure scale heights, too large to be explained by Rayleigh-scattering in the planetary atmosphere. Aims: We present a follow-up study of the optical transmission spectrum of the hot Jupiter TrES-3 b to investigate the strong increase in opacity towards short wavelengths found by a previous study. Furthermore, we aim to estimate the effect of stellar spots on the transmission spectrum. Methods: This work uses previously published long slit spectroscopy transit data of the Gran Telescopio Canarias (GTC) and published broad band observations as well as new observations in different bands from the near-UV to the near-IR, for a homogeneous transit light curve analysis. Additionally, a long-term photometric monitoring of the TrES-3 host star was performed. Results: Our newly analysed GTC spectroscopic transit observations show a slope of much lower amplitude than previous studies. We conclude from our results the previously reported increasing signal towards short wavelengths is not intrinsic to the TrES-3 system. Furthermore, the broad band spectrum favours a flat spectrum. Long-term photometric monitoring rules out a significant modification of the transmission spectrum by unocculted star spots. Based on (1) data obtained with the STELLA robotic telescopes in Tenerife, an AIP facility jointly operated by AIP and IAC, (2) observations collected at the German-Spanish Astronomical Center, Calar Alto, jointly operated by the Max-Planck-Institut für Astronomie Heidelberg and the Instituto de Astrofísica de Andalucía (CSIC) and (3) observations made with the Italian Telescopio Nazionale Galileo (TNG) operated on the island of La Palma by the Fundación Galileo Galilei of

  13. Trip report on IAEA Training Workshop on Implementation of Integrated Management Systems for Research Reactors (T3-TR-45496).

    Energy Technology Data Exchange (ETDEWEB)

    Pratt, Richard J.

    2013-11-01

    From 17-21 June 2013, Sandia National Laboratories, Technical Area-V (SNL TA-V) represented the United States Department of Energy/National Nuclear Security Administration (DOE/NNSA) at the International Atomic Energy Agency (IAEA) Training Workshop (T3-TR-45486). This report gives a breakdown of the IAEA regulatory structure for those unfamiliar, and the lessons learned and observations that apply to SNL TA-V that were obtained from the workshop. The Safety Report Series, IAEA workshop final report, and SNL TA-V presentation are included as attachments.

  14. An Automatic Framework Using Space-Time Processing and TR-MUSIC for Subsurface and Through-Wall Multitarget Imaging

    Directory of Open Access Journals (Sweden)

    Si-hao Tan

    2012-01-01

    Full Text Available We present an automatic framework combined space-time signal processing with Time Reversal electromagnetic (EM inversion for subsurface and through-wall multitarget imaging using electromagnetic waves. This framework is composed of a frequency-wavenumber (FK filter to suppress direct wave and medium bounce, a FK migration algorithm to automatically estimate the number of targets and identify target regions, which can be used to reduce the computational complexity of the following imaging algorithm, and a EM inversion algorithm using Time Reversal Multiple Signal Classification (TR-MUSIC to reconstruct hidden objects. The feasibility of the framework is demonstrated with simulated data generated by GPRMAX.

  15. Modelo origen destino para estimar el flujo de tráfico usando algoritmos genéticos

    OpenAIRE

    Aldás S., Milton R.; Flores C., Marco J.; Universidad de Cuenca; Dirección de Investigación de la Universidad de Cuenca; DIUC

    2014-01-01

    En este trabajo se ha desarrollado un nuevo método basado en Inteligencia Artificial para resolver un problema del matriz origen-destino (O-D) aplicado al caso de una red de tráfico vehicular en la ciudad de Ambato. El método implementado, basado en algoritmos genéticos (AG), resuelve el problema de minimización asociado al problema de matriz O-D. Para validar la técnica, se ha utilizado una red vial correspondiente a la zona del Mercado Modelo en la ciudad de Ambato, que es una zona de alta ...

  16. Os animais silvestres e a questão ambiental : legislação e tráfico

    OpenAIRE

    Erika Fernanda Tangerino Hernandez

    2003-01-01

    Desde o início de nossa colonização assistimos à degradação do meio ambiente e ao saque de nossas riquezas naturais. O presente trabalho procurou analisar questões relacionadas à fauna silvestre brasileira e ao tráfico de animais silvestres. Para atingir o escopo, entendemos que o melhor caminho seria uma análise de várias questões concernentes ao tema. Abordamos temas relativos à tutela jurídica, ao conceito de fauna, às causas de degradação ambiental que mais influenciam no extermínio da fa...

  17. El tráfico de órganos en Brasil: Civilconstitucional enderece contra la Mercantilización persona

    Directory of Open Access Journals (Sweden)

    Mara Conceição Vieira de Oliveira

    2016-06-01

    Full Text Available Pese haya regulación en el sistema jurídico brasileño, el Tráfico de órganos es problema serio, y medidas de prevención son poco discutidas y/o presentadas. La atrocidad del cri- men se vuelve poco creíble ante la sociedad, en la cual muchos entienden el tráfico de ór- ganos sólo como más una leyenda urbana. Este estudio cuestiona: ¿Cuál la efectividad de la regulación de la dignidad de la persona humana, cuando el cuerpo asume valor de “cosa”?, es decir, ¿Cuánto cuesta una persona o parte suya cuando transformada en producto en una sociedad de mercado? ¿Cuáles los límites jurídicos y morales son violados cuando un órgano está puesto a la venta? De esta manera, se objetiva, aquí, describir el principio de la dignidad de la persona humana y su efectividad en relación a este crimen, señalando el incumplimiento del Código Civil Brasileiro. Para eso, el procedimiento metodológico ele- gido se orientará por la investigación teórico bibliográfica, al realizar lecturas legislativas y doctrinarias; lectura crítica filosófica con Michael Sandel sobre la moralidad del mercado; y recopilación de datos sobre la base de la CPI del Tráfico de órganos – “CPIORGAO”. Los resultados obtenidos, hasta el momento actual, presentan recopilación teórico bibliográfi- ca; aún no se realizó análisis aplicada a los casos específicos citados por la comisión, a pesar de que puedan venir a ser estudiados en otras etapas del desarrollo de la investigación. La temática de este artículo, al relacionar la problemática del tráfico de órganos, la dignidad de la persona humana y la mercantilización del cuerpo, contribuye para el tema del evento: - Participación, Democracia y Ciudadanía en la perspectiva del Derecho Iberoameri- cano -, una vez que nuestro grupo de investigación también entiende la cuestión en este escenario de creciente y complejo proceso de globalización.

  18. Ecologia trófica do Octocoral Carijoa riisei (Duchassaing & Michelotti, 1860) (Cnidaria, Alcyonacea) em Porto de Galinhas (Pernambuco, Brasil)

    OpenAIRE

    Karla Francelino Lira, Ana

    2008-01-01

    Carijoa riisei constitui a espécie de octocoral mais abundante para a costa de Pernambuco. Visando conhecer a importância da espécie na cadeia trófica local, foi realizada uma pesquisa, subdividida em duas etapas: a primeira objetivando descobrir a composição alimentar e as possíveis flutuações sazonais e batimétricas na mesma; e, a segunda focando o grau de seletividade do octocoral pelas presas disponíveis no plâncton. As colônias do octocoral foram coletadas na Praia de Port...

  19. Characterizing Giant Exoplanets through Multiwavelength Transit Observations: HAT-P-14 b & TrES-1 b

    Science.gov (United States)

    Rivera, Daniel Ivan; Cole, Jackson Lane; Gardner, Cristilyn N.; Garver, Bethany Ray; Jarka, Kyla L.; Kar, Aman; McGough, Aylin Marie; PeQueen, David Jeffrey; Kasper, David; Jang-Condell, Hannah; Kobulnicky, Henry; Dale, Daniel

    2018-01-01

    Much current work focuses on characterizing exoplanets. We observed several known exoplanets using the 2.3 meter Wyoming Infrared Observatory over the course of ten weeks using the ugriz Sloan filters. Our goal was to quantify planet-to-star radius ratio, a ratio that is potentially wavelength dependent due to exoplanet atmospherics. We present the results for exoplanets HAT-P 14 b and TrES-1 b. Complementary data from the literature are utilized to supplement our analysis. This work is supported by the National Science Foundation under REU grant AST 1560461 and PAARE grant AST 1559559.

  20. PHOTOMETRICALLY DERIVED MASSES AND RADII OF THE PLANET AND STAR IN THE TrES-2 SYSTEM

    Energy Technology Data Exchange (ETDEWEB)

    Barclay, Thomas; Huber, Daniel; Rowe, Jason F.; Quintana, Elisa V.; Christiansen, Jessie L.; Jenkins, Jon M.; Mullally, Fergal; Seader, Shaun E.; Tenenbaum, Peter; Thompson, Susan E. [NASA Ames Research Center, M/S 244-30, Moffett Field, CA 94035 (United States); Fortney, Jonathan J.; Morley, Caroline V.; Fabrycky, Daniel C. [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States); Barentsen, Geert [Armagh Observatory, College Hill, Armagh BT61 9DG (United Kingdom); Bloemen, Steven [Instituut voor Sterrenkunde, Katholieke Universiteit Leuven, Celestijnenlaan 200 D, B-3001 Leuven (Belgium); Demory, Brice-Olivier [Department of Earth, Atmospheric and Planetary Sciences, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (United States); Fulton, Benjamin J.; Shporer, Avi [Las Cumbres Observatory Global Telescope Network, 6740 Cortona Drive, Suite 102, Santa Barbara, CA 93117 (United States); Ragozzine, Darin [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States)

    2012-12-10

    We measure the mass and radius of the star and planet in the TrES-2 system using 2.7 years of observations by the Kepler spacecraft. The light curve shows evidence for ellipsoidal variations and Doppler beaming on a period consistent with the orbital period of the planet with amplitudes of 2.79{sup +0.44}{sub -0.62} and 3.44{sup +0.32}{sub -0.37} parts per million (ppm), respectively, and a difference between the dayside and the nightside planetary flux of 3.41{sup +0.55}{sub -0.82} ppm. We present an asteroseismic analysis of solar-like oscillations on TrES-2A which we use to calculate the stellar mass of 0.94 {+-} 0.05 M{sub Sun} and radius of 0.95 {+-} 0.02 R{sub Sun }. Using these stellar parameters, a transit model fit and the phase-curve variations, we determine the planetary radius of 1.162{sup +0.020}{sub -0.024} R{sub Jup} and derive a mass for TrES-2b from the photometry of 1.44 {+-} 0.21 M{sub Jup}. The ratio of the ellipsoidal variation to the Doppler beaming amplitudes agrees to better than 2{sigma} with theoretical predications, while our measured planet mass and radius agree within 2{sigma} of previously published values based on spectroscopic radial velocity measurements. We measure a geometric albedo of 0.0136{sup +0.0022}{sub -0.0033} and an occultation (secondary eclipse) depth of 6.5{sup +1.7}{sub -1.8} ppm which we combined with the day/night planetary flux ratio to model the atmosphere of TrES-2b. We find that an atmosphere model that contains a temperature inversion is strongly preferred. We hypothesize that the Kepler bandpass probes a significantly greater atmospheric depth on the night side relative to the day side.

  1. Ulomci reljefa s prikazom Silvana i Dijane s lokaliteta Tršćenica u splitskome polju

    OpenAIRE

    Rendić-Miočević, Ante

    2007-01-01

    Lokalitet Tršćenica (Trišćenica, Trstenik) ime očigledno duguje trstici, biljci koja uspijeva samo na mjestima s dovoljnim količinama vode potrebne za njezin rast. Na jednoj od lokacija u splitskom polju, u blizini crkvice sv. Lovre od Pazdigrada i današnjega splitskog groblja Lovrinac, u različitim prigodama i okolnostima otkrivena su dva fragmentarna kamena reljefa; jedan s prikazom Silvana, popularnog domaćeg pastirsko-šumskog božanstva, a drugi s likom njegova ženskog...

  2. How to stir a revolution as a reluctant rebel: Rudolf Trümpy in the Alps

    Science.gov (United States)

    Şengör, A. M. Celâl; Bernoulli, Daniel

    2011-07-01

    Rudolf Trümpy (1921-2009) was one of the great Alpine geologists of the twentieth century and an influential figure in the international geological community. He played a dominant role in the change of opinion concerning the Alpine evolution by showing that normal faulting dominated the early development of the Alpine realm from the Triassic to the early Cretaceous. This provided a convenient model for later plate-tectonic interpretations of collisional mountain belts. His further recognition of strike-slip faulting during all stages of the Alpine evolution presaged the realisation that the Alps were not built by a simple open-and-shut mechanism. Trümpy was educated during an intellectual lull, a time when simplistic models of the earth behaviour inherited from the middle of the nineteenth century became prevalent under the influence of a close-minded, positivist approach to geological problems. This period, which we term the Dark Intermezzo, lasted from about 1925 to 1965. The grand syntheses of Suess and Argand which preceded this period were viewed from this narrow angle and consequently misunderstood. It was thought that earth history was punctuated by global orogenic events of short duration taking place within and among continents and oceans whose relative positions had remained fixed since the origin of the planet. These views, summarised under the term `fixism', were developed when the ocean floors were almost totally unknown. When data began coming in from the post World War II oceanographic surveys, the world geological community was slow to receive and digest them. Trümpy followed these developments closely, realising that his work was important in placing the geology of the mountain belts within the emerging, new theoretical framework. He adopted the position of a critic and emphasised where detailed knowledge of the Alps, unquestionably the best known mountain belt in the world, supported and where it contradicted the new ideas. His voice was

  3. A tríplice responsabilidade ambiental e a responsabilidade penal da pessoa jurídica

    Directory of Open Access Journals (Sweden)

    Carina Goulart da Silva

    2016-12-01

    Full Text Available A relevância jurídica do bem jurídico meio ambiente, tutelado pela disciplina de Direito Ambiental, justifica a necessidade de que este bem seja plenamente protegido. Assim, o artigo 225, parágrafo 3º, da Constituição Federal, e o artigo 3º da Lei 9.605/95, preveem a tríplice responsabilidade das pessoas físicas e jurídicas: responsabilidade administrativa, civil e penal por danos causados ao meio ambiente.

  4. Salud mental de migrantes centroamericanos indocumentados en tránsito por la frontera sur de México

    OpenAIRE

    César Infante-Xibille; Guadalupe Temores-Alcántara; Marta Caballero; Fátima Flores-Palacios; Nadia Santillanes-Allande

    2015-01-01

    Objetivo. Conocer las necesidades percibidas de salud mental de migrantes centroamericanos indocumentados en tránsito por la ciudad de Tapachula, Chiapas. Material  y métodos. Estudio cualitativo realizado en Casa de Migrantes de Tapachula, Chiapas. Se realizaron 20 entrevistas semiestructuradas a diez mujeres y diez hombres migrantes. Se exploró el estado de salud mental y las expectativas de atención. Se retomaron nociones teórico-metodológicas de la fenomenología sociológica. Resultados. L...

  5. Process Optimization of P(VDF-TrFE)-BaTiO3 Nanocomposites for Storage Capacitor Applications

    KAUST Repository

    Almadhoun, Mahmoud N.

    2011-07-11

    Increasing demands for efficient energy storage in microelectronics has pushed the scientific community towards finding suitable materials that can effectively deliver high pulse power in miniaturized systems. Polymer-ceramic composites are considered to be one possible solution towards the fabrication of high energy density capacitors, whether as embedded capacitors or gate insulators in organic field effect transistors (OFETs). Selecting high permittivity ceramics mixed with polymers with high breakdown field strengths would be the wisest approach towards enhancing energy storage. As such, novel ferroelectric polymers such as P(VDF-TrFE-CTFE) are being developed and researched, all displaying record dielectric values (K > 50) as promising candidates for high energy density composite capacitors (> 25 J/cm3). However, much work is still needed to understand the interaction mechanisms between the phases. We aim to seek an understanding of the processing challenges, especially in terms of fabricating thin film ferroelectric polymers and their application in nanocomposite capacitors while effectively maintaining optimized performance when embedded in flexible electronics. A process for synthesizing high performance P(VDF-TrFE) thin films is developed realizing the importance of controlling several process parameters to achieve high quality devices. Electrical and physicochemical characterization demonstrate how the performance of the polymer films improves with prolonged annealing periods by allowing sufficient time for solvent evaporation, crystallization and preferential-orientation of the crystallites. The polymer P(VDF-TrFE) is then used as a host material with barium titanate (BTO) nanoparticles below 100 nm (K = 150) as a ceramic filler in nanocomposite films. Facile surface modification by hydroxylation proved to be essential in the performance of the devices in terms of leakage current. A decrease of approximately 2 orders of magnitude in current leakage is

  6. T-R Cycle Characterization and Imaging: Advanced Diagnostic Methodology for Petroleum Reservoir and Trap Detection and Delineation

    Energy Technology Data Exchange (ETDEWEB)

    Ernest A. Mancini; William C. Parcell; Bruce S. Hart

    2005-09-19

    The principal research effort for Year 2 of the project is on stratigraphic model assessment and development. The research focus for the first six (6) months of Year 2 is on T-R cycle model development. The emphasis for the remainder of the year is on assessing the depositional model and developing and testing a sequence stratigraphy model. The development and testing of the sequence stratigraphy model has been accomplished through integrated outcrop, well log and seismic studies of Mesozoic strata in the Gulf of Mexico, North Atlantic and Rocky Mountain areas.

  7. Calibration of BAS-TR image plate response to high energy (3-300 MeV) carbon ions.

    Science.gov (United States)

    Doria, D; Kar, S; Ahmed, H; Alejo, A; Fernandez, J; Cerchez, M; Gray, R J; Hanton, F; MacLellan, D A; McKenna, P; Najmudin, Z; Neely, D; Romagnani, L; Ruiz, J A; Sarri, G; Scullion, C; Streeter, M; Swantusch, M; Willi, O; Zepf, M; Borghesi, M

    2015-12-01

    The paper presents the calibration of Fuji BAS-TR image plate (IP) response to high energy carbon ions of different charge states by employing an intense laser-driven ion source, which allowed access to carbon energies up to 270 MeV. The calibration method consists of employing a Thomson parabola spectrometer to separate and spectrally resolve different ion species, and a slotted CR-39 solid state detector overlayed onto an image plate for an absolute calibration of the IP signal. An empirical response function was obtained which can be reasonably extrapolated to higher ion energies. The experimental data also show that the IP response is independent of ion charge states.

  8. Čezmejno sodelovanje na primeru občine Tržič = The crossborder cooperation: a case study of the Tržič municipality

    Directory of Open Access Journals (Sweden)

    Irena Mrak

    1998-01-01

    Full Text Available The Municipality of Tržič borders with the Republic of Austria at the main ridge of the Karavanke mountain. Cooperation with the neighbouring communities Borovlje/Ferlach and Sele/Zell Pfare started in the eighties and it has become more intense after the year 1991. The border that was once separating the inhabitants on both sides of the mountain ridge has become more opened after the slovenian independence but the border control is after Schengen agreement more severe. Remote mountain border areas where access used to be limited were suddenly recognised as a great touristic potential. In the recent years the Municipality of Tržič together with Austrian partners managed to form some joined agriculture and tourism development projects within the PHARE programme (CBC - Crossborder Cooperation and ECOS - Ouverture. The projects deal with the regrowing of buckwheat, preservation of a special sheep breed - jezersko solčavska sheep, activation of the natural monument Dovžan gorge which will be logistically connected to Tscheppa gorge on the austrian side. Within the ECOS Ouverture programme the project of Thematic trails around the Košuta mountain has been initiated in order to reactivate and connect hidden natural and cultural potentials into integrated touristic offer of this part of the Karavanke mountain.

  9. Síndrome de Klippel-Trenaunay-Parkes-Weber com angiomatose medular Klippel-Trénaunay-Parkes-Weber syndrome with spinal cord angioma: a case report

    Directory of Open Access Journals (Sweden)

    James Pitagoras de Mattos

    1975-09-01

    Full Text Available É relatado um caso de síndrome de Klippel-Trénaunay-Parkes-Weber associada a angiomatose medular. O autor salienta ter encontrado na literatura somente uma referência com tal associação.A case of Klippel-Trénaunay-Parkes-Weber syndrome associated with spinal cord angioma is reported. The author points out that it was found only one reference in literature with such association.

  10. Transformative piezoelectric enhancement of P(VDF-TrFE) synergistically driven by nanoscale dimensional reduction and thermal treatment.

    Science.gov (United States)

    Ico, G; Myung, A; Kim, B S; Myung, N V; Nam, J

    2018-02-08

    Despite the significant potential of organic piezoelectric materials in the electro-mechanical or mechano-electrical applications that require light and flexible material properties, the intrinsically low piezoelectric performance as compared to traditional inorganic materials has limited their full utilization. In this study, we demonstrate that dimensional reduction of poly(vinylidene fluoride trifluoroethylene) (P(VDF-TrFE)) at the nanoscale by electrospinning, combined with an appropriate thermal treatment, induces a transformative enhancement in piezoelectric performance. Specifically, the piezoelectric coefficient (d 33 ) reached up to -108 pm V -1 , approaching that of inorganic counterparts. Electrospun mats composed of thermo-treated 30 nm nanofibers with a thickness of 15 μm produced a consistent peak-to-peak voltage of 38.5 V and a power output of 74.1 μW at a strain of 0.26% while sustaining energy production over 10k repeated actuations. The exceptional piezoelectric performance was realized by the enhancement of piezoelectric dipole alignment and the materialization of flexoelectricity, both from the synergistic effects of dimensional reduction and thermal treatment. Our findings suggest that dimensionally controlled and thermally treated electrospun P(VDF-TrFE) nanofibers provide an opportunity to exploit their flexibility and durability for mechanically challenging applications while matching the piezoelectric performance of brittle, inorganic piezoelectric materials.

  11. Involucramiento del Padre en la Crianza: Una Mirada Tríadica de las Relaciones Familiares Tempranas

    Directory of Open Access Journals (Sweden)

    Francisca Pérez Cortés

    2014-11-01

    Full Text Available Considerando los beneficios de una paternidad activa en el desarrollo de niños y niñas, así como en las dinámicas familiares en general, los profesionales del área de la salud deben ser agentes activos en la promoción de la participación de madres y padres en la crianza. El siguiente artículo busca introducir en el contexto nacional una herramienta que amplía la mirada del desarrollo infantil y las relaciones al interior de la familia, desde la díada a la tríada. El Lausanne Trilogue Play (LTP es una herramienta observacional, desarrollada por Fivaz-Depeursinge, Frascarolo y Corboz-Warnery (1996 que permite la evaluación estandarizada de la “alianza familiar”, corroborando la importancia de incorporar al padre en los estudios de procesos e interacciones familiares, así como la existencia de un efecto familiar tríadico desde etapas tempranas.

  12. Comparative analysis of LytS/LytTR-type histidine kinase/response regulator systems in γ-proteobacteria.

    Directory of Open Access Journals (Sweden)

    Stefan Behr

    Full Text Available Bacterial histidine kinase/response regulator systems operate at the interface between environmental cues and physiological states. Escherichia coli contains two LytS/LytTR-type histidine kinase/response regulator systems, BtsS/BtsR (formerly YehU/YehT and YpdA/YpdB, which have been identified as pyruvate-responsive two-component systems. Since they exhibit remarkable similarity, we analyzed their phylogenetic distribution within the γ-proteobacteria, and experimentally characterized them in a set of representative species. We found that BtsS/BtsR is the predominant LytS/LytTR-type two-component system among γ-proteobacteria, whereas YpdA/YpdB primarily appears in a supplementary role. Based on our observations in E. coli, we used the highly conserved DNA-binding motifs to test the in vivo functionality of both systems in various genera, including Salmonella, Enterobacter, Citrobacter, Xenorhabdus, Yersinia, Aeromonas and Vibrio. The results suggest that, in all cases tested, BtsS/BtsR and YpdA/YpdB respond to different levels of pyruvate in the environment.

  13. Diferentes como só nós. O associativismo GLBT português em três andamentos

    Directory of Open Access Journals (Sweden)

    António Fernando Cascais

    2012-10-01

    Full Text Available O presente texto toma como eixo de análise o modo como a diferença específica da formação social portuguesa determina e se exprime na sociogénese do associativismo GLBT nas três últimas décadas. É possível traçar uma periodização dele em três estádios, à qual deve atribuir‑se sobretudo um valor heurístico: o primeiro de 1974 até 1991, que pode dividir‑se em duas fases, uma anterior e outra posterior ao surgimento da epidemia de Sida no nosso país; o segundo, entre 1990-1991 e 1995-1997; e o terceiro, de 1997 até ao presente. A produção de conhecimento sobre o associativismo GLBT tem ainda de se articular com duas outras pesquisas: sobre os seus detractores e inimigos, antigos e neófitos, e sobre a comunidade que o associativismo representa ou de que emerge, com uma história, uma identidade e uma cultura que explicam as razões da adesão ou da resistência a ele.

  14. Salud mental de migrantes centroamericanos indocumentados en tránsito por la frontera sur de México

    Directory of Open Access Journals (Sweden)

    César Infante-Xibille

    2015-05-01

    Full Text Available Objetivo. Conocer las necesidades percibidas de salud mental de migrantes centroamericanos indocumentados en tránsito por la ciudad de Tapachula, Chiapas. Material  y métodos. Estudio cualitativo realizado en Casa de Migrantes de Tapachula, Chiapas. Se realizaron 20 entrevistas semiestructuradas a diez mujeres y diez hombres migrantes. Se exploró el estado de salud mental y las expectativas de atención. Se retomaron nociones teórico-metodológicas de la fenomenología sociológica. Resultados. Los migrantes presentaban signos y síntomas de daños en su salud mental relacionados con experiencias vividas en el lugar de origen y en el tránsito por México. La percepción sobre su salud mental es influida por el modelo biomédico hegemónico. Las expectativas de servicios se relacionaron con la satisfacción de necesidades básicas. Conclusiones. Es necesario fortalecer la respuesta del sistema de atención en salud mental a partir de estrategias de cooperación y emprender acciones que promuevan la superación de una construcción biomédica de salud mental que estigmatiza, medicaliza, segrega y dificulta el acceso a servicios.

  15. Gentle dry etching of P(VDF-TrFE) multilayer micro actuator structures by use of an inductive coupled plasma

    International Nuclear Information System (INIS)

    Edqvist, E; Snis, N; Johansson, S

    2008-01-01

    To fully utilize the actuator properties of poly(vinylidenefluoride) (P(VDF))-based polymers, the electric field has to be rather high and one way to accomplish this, in particular with low voltage drive signals, is to build multilayered structures. This paper focuses on how to structure poly(vinylidenefluoride-trifluoroethylene) P(VDF-TrFE) by presenting an etch method to create multilayered miniaturized actuators, with intermediate aluminium electrodes. To create inter-connect areas for the multilayer electrodes, a modified Bosch process in an inductive couple plasma (ICP) etcher is used to remove all P(VDF-TrFE) not covered by the electrodes. Since each electrode mask is slightly different from the others, the result is a staircase-like inter-electrode contact area that is connected from above using a conductive adhesive. The developed ICP etch results in high selective etching and a good agreement between theoretical and measured capacitance values. The manufactured cantilevers, consisting of a multilayer on top of a flexible printed circuit (FPC) board, were tested and the resonant stroke was confirmed to agree with expected values. The successful establishment of interlayer connections between the electrodes open up the possibility for batch fabrication of cheap low voltage micro actuators built on a standard substrate used in millions of commercial products

  16. Parasite community of Cichla kelberi (Perciformes, Cichlidae) in the Três Marias Reservoir, Minas Gerais, Brazil.

    Science.gov (United States)

    Santos-Clapp, Michelle Daniele; Brasil-Sato, Marilia Carvalho

    2014-01-01

    A total of 112 specimens of yellow peacock bass, Cichla kelberi, were collected in the Três Marias Reservoir, upper São Francisco River, State of Minas Gerais, between 2004 and 2005. Twelve species of parasites were collected: two species of ectoparasites (the monogenetic Gussevia sp. and the copepod Ergasilus sp.); and ten species of endoparasites, including four species of adult endoparasites: the cestodes Proteocephalus macrophallus and P. microscopicus, and the nematodes: Capillostrongyloides sentinosa and Rhabdochona acuminata, and six species of larval endoparasites: the metacercariae of Austrodiplostomum compactum and the nematodes: Hysterothylacium sp., Contracaecum sp. Type 1, Procamallanus (Spirocamallanus) inopinatus, Spiroxys sp., and Goezia sp.. A significant positive correlation in the abundance of the two adult endoparasites species, P. macrophallus and P. microscopicus, may indicate that such associated species had the same ecological requirements. The positive correlations between the prevalence of the larval endoparasites, Hysterothylacium sp. and A. compactum, may indicate that there was opportunism for the two generalists species. Ergasilus sp., C. sentinosa, R. acuminata and Hysterothylacium sp. were recorded for the first time in C. kelberi, and this increased their list of known hosts. In addition, both proteocephalid species and C. sentinosa can extend their known biogeographical distribution to the Três Marias Reservoir.

  17. Parasite Community of Cichla kelberi (Perciformes, Cichlidae in the Três Marias Reservoir, Minas Gerais, Brazil

    Directory of Open Access Journals (Sweden)

    Michelle Daniele Santos-Clapp

    Full Text Available A total of 112 specimens of yellow peacock bass, Cichla kelberi, were collected in the Três Marias Reservoir, upper São Francisco River, State of Minas Gerais, between 2004 and 2005. Twelve species of parasites were collected: two species of ectoparasites (the monogenetic Gussevia sp. and the copepod Ergasilus sp.; and ten species of endoparasites, including four species of adult endoparasites: the cestodes Proteocephalus macrophallus and P. microscopicus, and the nematodes: Capillostrongyloides sentinosa and Rhabdochona acuminata, and six species of larval endoparasites: the metacercariae of Austrodiplostomum compactum and the nematodes: Hysterothylacium sp., Contracaecum sp. Type 1, Procamallanus (Spirocamallanus inopinatus, Spiroxys sp., and Goezia sp.. A significant positive correlation in the abundance of the two adult endoparasites species, P. macrophallus and P. microscopicus, may indicate that such associated species had the same ecological requirements. The positive correlations between the prevalence of the larval endoparasites, Hysterothylacium sp. and A. compactum, may indicate that there was opportunism for the two generalists species. Ergasilus sp., C. sentinosa, R. acuminata and Hysterothylacium sp. were recorded for the first time in C. kelberi, and this increased their list of known hosts. In addition, both proteocephalid species and C. sentinosa can extend their known biogeographical distribution to the Três Marias Reservoir.

  18. Examining sex differences in DSM-IV-TR narcissistic personality disorder symptom expression using Item Response Theory (IRT).

    Science.gov (United States)

    Hoertel, Nicolas; Peyre, Hugo; Lavaud, Pierre; Blanco, Carlos; Guerin-Langlois, Christophe; René, Margaux; Schuster, Jean-Pierre; Lemogne, Cédric; Delorme, Richard; Limosin, Frédéric

    2017-12-14

    The limited published literature on the subject suggests that there may be differences in how females and males experience narcissistic personality disorder (NPD) symptoms. The aim of this study was to use methods based on item response theory to examine whether, when equating for levels of NPD symptom severity, there are sex differences in the likelihood of reporting DSM-IV-TR NPD symptoms. We conducted these analyses using a large, nationally representative sample from the USA (n=34,653), the second wave of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). There were statistically and clinically significant sex differences for 2 out of the 9 DSM-IV-TR NPD symptoms. We found that males were more likely to endorse the item 'lack of empathy' at lower levels of narcissistic personality disorder severity than females. The item 'being envious' was a better indicator of NPD severity in males than in females. There were no clinically significant sex differences on the remaining NPD symptoms. Overall, our findings indicate substantial sex differences in narcissistic personality disorder symptom expression. Although our results may reflect sex-bias in diagnostic criteria, they are consistent with recent views suggesting that narcissistic personality disorder may be underpinned by shared and sex-specific mechanisms. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. O diálogo intertextual com Fernando Pessoa em três contos de José Eduardo Agualusa

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    Altamir Botoso

    2016-01-01

    Full Text Available O artigo centra-se no estudo de três contos do escritor angolano José Eduardo Agualusa (1960-: Se nada mais der certo leia Clarice, Catálogo de sombras e Livre-arbítrio, que fazem parte do seu livro Manual prático de levitação (2005. Buscaremos evidenciar a presença do poeta português Fernando Pessoa (1888-1935 e de seus heterônimos, Alberto Caeiro, Ricardo Reis e Álvaro de Campos, nos três contos mencionados, pautados por considerações do próprio Agualusa, que procura estabelecer, por meio de sua obra, um diálogo frequente entre as literaturas africana, brasileira e portuguesa, em conformidade com a sua postura de divulgar a cultura e, em particular, a literatura africana para o mundo, diluindo fronteiras que possam separar as literaturas de expressão portuguesa. Nas análises dos textos selecionados, empregaremos como suporte teórico os escritos de Julia Kristeva (1974, Leyla Perrone-Moisés (1990, Tiphaine Samoyault (2008 e Laurent Jenny (1979.

  20. P(VDF-TrFE)/ZrO{sub 2} polymer-composites for X-ray shielding

    Energy Technology Data Exchange (ETDEWEB)

    Fontainha, Crissia Carem Paiva [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Dept. de Engenharia Nuclear; Baptista Neto, Annibal Theotonio; Santos, Adelina Pinheiro; Faria, Luiz Oliveira de, E-mail: farialo@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2016-03-15

    Poly(vinylidene fluoride - tryfluorethylene) [P(VDF-TrFE)] copolymers were mixed with zirconia nanoparticles. The investigation was conducted with the intention to produce nanocompounds with potential to be used as protective patient shielding in radiological procedures. Polymer based nanocomposites with 1, 2, 3, 5 and 10 wt% of ZrO{sub 2} nanoparticles were prepared using sol-gel route with zirconium butoxide as the precursor for zirconium oxide nanoclusters. UV-Vis and FTIR spectrometry and differential scanning calorimetry (DSC) were used to characterize the composite samples. We observed a more homogeneous distribution of ZrO{sub 2} nanoparticles encapsulated by methyl methacrylate (MMA) into the polymeric matrix, when compared to composites made without the use of surface modifiers from methacrylate group. Apparently, this property is related to the absence of the strong MMA absorption band at 1745 cm{sup -1}, attributed to C=O bond, in the P(VDF-TrFE)/ZrO{sub 2} -MMA nanocomposites. The radiation damage due to high dose exposure was performed for gamma doses ranging from 100 kGy to 1,000 kGy. The radiation shielding characterization conducted using x-rays with effective energy of 40 keV has demonstrated that composites with 10% of ZrO{sub 2}, and only 1.0 mm thick, can attenuate 60% of the x-rays beam. (author)

  1. Trânsito coletivo e comportamento individual:metáfora de antígona: metáfora de antígona

    Directory of Open Access Journals (Sweden)

    Diogo Picchioni Soares

    Full Text Available Este ensaio aborda reflexões sobre trânsito a partir da tragédia de Antígona, de Sófocles. A riqueza e a profundidade dessa tragédia permitem extrair metáforas para orientar debates sobre as situações de conflito que permeiam o cotidiano do trânsito. O texto está estruturado em quatro tópicos; a a síntese da tragédia, para que possam ser identificados os elementos que orientam as reflexões; b considerações sobre quem é o outro na tragédia e no espaço do trânsito; c discussão sobre a articulação entre espaço público e espaço privado no cotidiano do trânsito; e d diálogo entre aspectos do comportamento individual que permitem desenvolver um comportamento coletivo, demandado pelas múltiplas interações que emergem no espaço público do trânsito. As reflexões sintetizam metáforas que indicam a importância de orientar as ações no trânsito, destacando a compreensão da rede de consequências de decisões e de ações quando negligenciam a interação com o outro e a repercussão para a própria sobrevivência. São indicadas três dimensões dessas reflexões: o conflito pode gerar morte; há diferentes maneiras de compreender as ações de um e de outro personagem; é a reflexão compartilhada que permite incorporar o ponto de vista do outro.

  2. Trama trófica de una comunidad de peces en una pradera marina en el Caribe Venezolano

    Directory of Open Access Journals (Sweden)

    Adriana López-Ordaz

    2009-12-01

    Full Text Available Las praderas marinas son consideradas sitios importantes de alimentación para una variedad de especies de peces, por lo que en estos sistemas son frecuentes las interacciones tróficas complejas. En el presente trabajo se describió la trama trófica de la ictiofauna en una pradera marina ubicada en el Caribe Venezolano. Adicionalmente, se propuso una medida de la intensidad de consumo de cada presa (IC, considerando dos variables: la abundancia y la frecuencia de uso. Se realizaron ocho muestreos (en 4 horarios: 6:00, 12:00, 18:00 y 24:00 horas en agosto 2005 y enero 2006. Se capturaron 51 especies pertenecientes a 29 familias siendo Haemulidae la más abundante y se identificaron 28 items alimenticios dentro de los cuales, Crustácea fue el más importante como recurso alimenticio. La importancia de los gremios tróficos considerando la abundancia y la riqueza taxonómica de especies fue: bentófago>herbívoro>piscívoro. Las características de la trama trófica fueron las siguientes: 1 una mayor proporción de cadenas cortas (dos eslabones, 2 un elevado número de especies intermedias. 3 un elevado consumo de bentos, 4 unas bajas intensidades de consumo y 5 un reducido número de especies involucradas en el mayor número de uniones tróficas estimadas. Se obtuvieron diferencias temporales (horarias y mensuales en el número de especies (totales, intermedias y topes, de uniones totales, en la conectividad y en la longitud máxima de cadena. No se observó una variación temporal en la conectancia y sus valores resultaron parecidos a los reportados para otros ambientes marinos con distinta riqueza de especies. Por el contrario, los valores de conectividad resultaron menores a los obtenidos en ambientes con menor riqueza de especies. Como en otros reportes, los parámetros tróficos estimados fueron poco sensibles a los cambios intracomunitarios. IC resultó bajo, a excepción de lo obtenido para los copépodos harpacticoides y las larvas de

  3. In vitro activity and microbiological efficacy of tedizolid (TR-700) against Gram-positive clinical isolates from a phase 2 study of oral tedizolid phosphate (TR-701) in patients with complicated skin and skin structure infections.

    Science.gov (United States)

    Prokocimer, Philippe; Bien, Paul; Deanda, Carisa; Pillar, Chris M; Bartizal, Ken

    2012-09-01

    Tedizolid (TR-700, formerly torezolid) is the active moiety of the prodrug tedizolid phosphate (TR-701), a next-generation oxazolidinone, with high potency against Gram-positive species, including methicillin-resistant Staphylococcus aureus (MRSA). A recently completed randomized, double-blind phase 2 trial evaluated 200, 300, or 400 mg of oral tedizolid phosphate once daily for 5 to 7 days in patients with complicated skin and skin structure infections. This report examines the in vitro activity of tedizolid and Zyvox (linezolid) against Gram-positive pathogens isolated at baseline and describes the microbiological and clinical efficacy of tedizolid. Of 196 isolates tested, 81.6% were S. aureus, and of these, 76% were MRSA. The MIC(50) and MIC(90) of tedizolid against both methicillin-susceptible S. aureus (MSSA) and MRSA were 0.25 μg/ml, compared with a MIC(50) of 1 μg/ml and MIC(90) of 2 μg/ml for linezolid. For coagulase-negative staphylococci (n = 7), viridans group streptococci (n = 15), and beta-hemolytic streptococci (n = 3), the MICs ranged from 0.03 to 0.25 μg/ml for tedizolid and from 0.12 to 1 μg/ml for linezolid. The microbiological eradication rates at the test-of-cure visit (7 to 14 days posttreatment) in the microbiologically evaluable population (n = 133) were similar in all treatment groups, with overall eradication rates of 97.7% for all pathogens, 97.9% for MRSA, and 95.7% for MSSA. The clinical cure rates for MRSA and MSSA infections were 96.9% and 95.7%, respectively, across all dose groups. This study confirms the potent in vitro activity of tedizolid against pathogenic Gram-positive cocci, including MRSA, and its 4-fold-greater potency in comparison with linezolid. All dosages of tedizolid phosphate showed excellent microbiological and clinical efficacy against MRSA and MSSA.

  4. Características psicométricas e dados normativos do Teste das Três Palavras e Três Figuras (3P3F no Brasil

    Directory of Open Access Journals (Sweden)

    Moura, Samara Melo

    2008-01-01

    Full Text Available O Teste das Três Palavras e Três Figuras (3P3F é um instrumento de avaliação rápida e multidimensional da memória episódica, desenvolvido para idosos. Ele ocuparia posição intermediária entre o item de memória do Mini Exame do Estado Mental (MEEM e tarefas mais complexas de listas de figuras e palavras. As características psicométricas de uma adaptação brasileira do 3P3F para amostras de 33 portadores de doença de Alzheimer (DA e 99 idosos cognitivamente normais demograficamente pareados foram investigadas. Adicionalmente, normas de desempenho foram desenvolvidas em um grupo de 350 idosos saudáveis. Os resultados revelam alta confiabilidade (a = 0,89 e poder descriminativo para a identificação das desordens cognitivas associadas à DA (ASC = 0,98; sensibilidade/especificidade = 94,9/92,3%. Observou-se a correlação do 3P3f com o MEEM e a Bateria de Avaliação Frontal (r = 0,65 e r = 0,46; p <0,05. Um modelo de regressão logística sugere a influência da idade e da escolaridade sobre os escores dos testes (B = 0,06 e B = 0,13; P <0,05. Os resultados sugerem adequação psicométrica do instrumento

  5. Mortes no trânsito do Rio de Janeiro, Brasil Traffic deaths in Rio de Janeiro, Brazil

    Directory of Open Access Journals (Sweden)

    Carlos Henrique Klein

    1994-01-01

    Full Text Available A evolução urbana do município do Rio de Janeiro durante o século XX, especialmente a partir da sua segunda metade, é fortemente marcada por crescentes privilégios concedidos ao crescimento da utilização dos meios de transporte de massa e, principalmente, individuais, feitos por veículos a motor de explosão. Uma das conseqüências desta política é a ascenção da mortalidade por acidentes de trânsito, verificada durante a década de 80, entre homens e mulheres de todas as idades. Neste trabalho demonstra-se também que, em 1990, apenas cerca de 1/3 das vítimas fatais nos acidentes de trânsito estavam "embarcadas" nos veículos. Portanto, a maioria dos óbitos por este tipo de acidente, cerca de 2/3, ocorreu por atropelamentos. Isto indica a necessidade de o poder público reverter a prioridade na prevenção das mortes por acidentes de trânsito em favor de medidas eficazes que protejam os pedestres.The evolution of the city of Rio de Janeiro during the 20th century, particularly since 1950, has been strongly characterized by increasing concession of privileges for the use of motor vehicles for both mass (and especially individual transportation. One of the main consequences of this policy was a rising mortality rate due to traffic accidents during the 1980s, among men and women of all ages. This paper demonstrates that in 1990 only about one-third of the fatal victims of traffic accidents were inside the vehicles involved. In Rio de Janeiro, the majority of deaths from this kind of accident (approximately two-thirds were pedestrians. Thus, policies aimed at reducing traffic-related mortality should give priority to the protection of pedestrians rather than drivers.

  6. Discursos i llenguatges pacifistes a Catalunya entre la Setmana Tràgica i la Guerra Civil, 1909 -1936

    OpenAIRE

    Devesa Pájaro, David

    2016-01-01

    [cat] Aquesta tesi doctoral té com a objectiu l’anàlisi dels discursos pacifistes publicats a Catalunya entre la Setmana Tràgica (1909) i l’inici de la Guerra Civil (1936). Per tal d’assolir aquest propòsit es parteix de la delimitació conceptual del propi terme “pacifisme” i del coneixement de la seva trajectòria històrica fins al segle XIX. Aquest marc teòric ens permetrà diseccionar, organitzar i comprendre les fonts consultades per acabar traçant un retrat de la penetració i consolidació ...

  7. Identidades en tránsito urbano: prácticas corporales en desplazados hacia Medellín

    Directory of Open Access Journals (Sweden)

    Rubiela Arboleda Gómez

    2013-01-01

    Full Text Available En este artículo se presentan hallazgos de la investigación “Improntas política-motricidad y su mediación en la relación cuerpo-ciudad de los desplazados hacia la ciudad de Medellín”, realizado entre el 2010 y el 2012. Se propone identificar prácticas emergentes relativas a la dimensión política en nexo con la motricidad, que favorecen la reconfiguración identitaria en el tránsito rural-urbano, producto del destierro y en el marco del conflicto armado en Colombia. Se concluye con el papel de la política vinculada al cuerpo en el proceso de adaptación de los sujetos desterrados en la ciudad.

  8. O estatismo: subjetividade e espaço nos «Três Contos», de Flaubert

    Directory of Open Access Journals (Sweden)

    Maria Elvira Malaquias de Carvalho

    2012-08-01

    Full Text Available Resumo: Enunciado originalmente por Lukács, o termo estatismo relaciona-se a procedimentos narrativos observados na vanguarda literária. Este texto tem o objetivo de utilizar tal nomenclatura como um conceito-chave para a compreensão dos Três contos, de Flaubert, levando em conta a representação da subjetividade e do espaço nesta obra. Palavras-chave: Estatismo; subjetividade; espaço; Flaubert.Abstract: The term statism originally used by Lukács is related to narrative procedures observed on literary vanguard. The aim of the present study is to use this terminology as a key concept for an understanding of the Three tales, by Flaubert, considering the representation of subjectivity and space in that text. Keywords: Statism; subjectivity; space; Flaubert.

  9. Análise do discurso e vitimologia: memória(s) de tráfico de drogas

    OpenAIRE

    Lucas do Nascimento

    2011-01-01

    Este estudo centra-se na relevância do discurso em todas as práticas sociais. Entre essas, encontram-se as práticas do judiciário, regulamentadas por leis, códigos penais, criminais, civis que tentam regular a maioria das relações sociais. Levando em conta o crime tráfico de drogas, o objetivo deste trabalho é compreender a posição-sujeito no processo de (des) construção do discurso do sujeito jurídico defensor, em processo penal concluso com absolvição de um dos réus infratores. Permanecendo...

  10. Aporia e passagem: a sobrevivência do "trágico" em Guimarães Rosa

    Directory of Open Access Journals (Sweden)

    Ettore Finazzi-Agrò

    2002-03-01

    Full Text Available O intuito deste texto é pôr em questão a persistência do “pensamento trágico” em Grande sertão: veredas, a partir de uma reflexão sobre o estatuto essencialmente (i.e., ontologicamente aporético da obra de João Guimarães Rosa. Romance da espera, de fato, ele se inclui por completo naquele lugar “terceiro”, suspenso entre esperança e desespero, que se delineia no interior de qualquer contradição e que constitui, desde sempre, o logos da tragédia.

  11. Myxome du ventricule droit chez un enfant: une présentation très rare

    Science.gov (United States)

    Tarmiz, Amine; Mgarrech, Imene; Slim, Mehdi; Kortas, Chokri; Jerbi, Sofiane

    2016-01-01

    Le myxome du ventricule droit est une localisation très rare des myxomes cardiaques. Les complications les plus fréquentes sont l'embolie pulmonaire et l'obstruction par la tumeur de la valve pulmonaire. Nous rapportons le cas d'un enfant âgé de 11 ans admis en Cardiologie pour des syncopes à répétition. L'échographie cardiaque met en évidence un myxome du ventricule droit de 2cm, obstruant l'orifice pulmonaire. L'exérèse chirurgicale est pratiquée en urgence sous circulation extracorporelle, avec des suites opératoires favorables. L'examen anatomopathologique de la pièce a permis de confirmer le diagnostic de myxome. Le suivi à 18 mois ne montre pas de récidive tumorale. PMID:28292100

  12. Modelos bayesianos de predicción y gestión de tráfico

    OpenAIRE

    Pilamunga Poveda, Efraín Marcelo

    2015-01-01

    Tesis Doctoral leída en la Universidad Rey Juan Carlos de Madrid en 2015. Directores de la Tesis: Javier Martínez Moguerza David Ríos Insua y José María Lavín La inversión orientada a la gestión de actividades integradas para un mejor desarrollo comunitario determina el progreso de una ciudad. Así, generar acciones encaminadas al cambio, evolución y mejora de la calidad de vida promueve una mayor satisfacción entre sus habitantes. El tránsito es uno de los factores más importantes en mejor...

  13. Carbon Molecular Sieve Membranes Derived from Tröger's Base-Based Microporous Polyimide for Gas Separation.

    Science.gov (United States)

    Wang, Zhenggong; Ren, Huiting; Zhang, Shenxiang; Zhang, Feng; Jin, Jian

    2018-03-09

    Carbon molecular sieve (CMS)-based membranes have attracted great attention because of their outstanding gas-separation performance. The polymer precursor is a key point for the preparation of high-performance CMS membranes. In this work, a microporous polyimide precursor containing a Tröger's base unit was used for the first time to prepare CMS membranes. By optimizing the pyrolysis procedure and the soaking temperature, three TB-CMS membranes were obtained. Gas-permeation tests revealed that the comprehensive gas-separation performance of the TB-CMS membranes was greatly enhanced relative to that of most state-of-the-art CMS membranes derived from polyimides reported so far. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Verification the 25-kgy dose using the iso standard iso/tr 13409 for the production of bone grafts

    International Nuclear Information System (INIS)

    Otero, I.; Barrera, L.; Diaz, A.; Napoles, D.; Sanchez, E

    2001-01-01

    The purpose of this work was to verify the 25 Gy dose using the ISO standard ISO/TR 13409 for the production of bone grafts from the Tissue Bank ORTOP of the Complejo Cientifico Ortopedico Internacional Frank Pais. We performed two principal microbiological activities: bioburden estimate, pre-sterilization count plus a compensation for the efficiency of the recovery method, by ISO 11737-1 and test of sterility by ISO 11737-2. The techniques for Bioburden estimation could be direct or indirect. Choice of direct vs. indirect depends on number of contaminating micro-organisms, product configuration, ability to remove microbial contamination, effect of removal method on microbial viability, types and location of micro-organisms, nature of product and culture conditions. For a test of sterility, he product unit or SIP putted direct immersion in educated culture medium and incubate. Keep precaution to minimize level to the false positives is necessary

  15. El trébol subterráneo (Trifolium subterraneum L) en los suelos calcáreos

    OpenAIRE

    Salgueiro, F. A.

    2011-01-01

    Se investigó la adaptación de dos cultivares de trébol subterráneo (Clare y Seaton Park) a los suelos calcáreos. En experimentos de laboratorio se sembró Clare en un suelo pardo calcáreo (Pe') con pH 8 y 75,7 % de carbonatos, y en un "barro" negro calcáreo fuertemente decarbonatado (Bpc), con pH 7,1 a 7,3 y trazas de carbonatos. En este último se aplicó cal en cantidades de 0, 2.000, 4.000 y 6.000 Kg./Ha. Aunque los rendimientos de materia seca no eran diferentes, las plantas que crecieron en...

  16. Do turista ao viajante: um olhar em trânsito nas fotografias de Luiz Carlos Felizardo

    Directory of Open Access Journals (Sweden)

    Lucas de Toledo Martins

    2014-09-01

    Full Text Available Este artigo se propõe a problematizar a relação homem-meio ambiente, relacionando-a com o conceito de viagem a partir da análise de parte da exposição intitulada Em trânsito, do arquiteto e fotógrafo Luiz Carlos Felizardo. As imagens foram feitas livremente por ele durante suas férias na França e, por isso, o fotógrafo afirmou que não teve a intenção de realizar um ensaio sobre o país. No entanto, valemo-nos dos conceitos de John Berger, Michel Maffesoli e Alain de Botton para demonstrar que o modo de ver de Felizardo escapa às determinações superficiais de envolvimento com o lugar, ou seja, da concepção do turista.

  17. O roubo de escravos no Rio de Janeiro e o tráfico interno paralelo: 1808-1850

    Directory of Open Access Journals (Sweden)

    Luiz Carlos Soares

    1989-07-01

    Full Text Available A documentação policial da Côrte na primeira metade do século passado evidencia a freqüência de um comércio ilícito de escravos roubados e revendidos para as províncias vizinhas. Delineia-se a par do tráfico internacional de contrabando, um comércio marginal a preços bem menores, controlados em sua maioria por ciganos e seus intermediários. Também envolvia capitães de mato ou quadrilhas muito bem organizadas. Era um meio de fornecer mão-de-obra mais barata a pequenos proprietários. Por vezes este comércio envolvia libertos em alforria condicional, evidenciando uma circulação clandestina de parentes escravos.

  18. Proibicionismo e a criminalização de adolescentes pobres por tráfico de drogas

    OpenAIRE

    Rocha,Andréa Pires

    2013-01-01

    O proibicionismo, a "guerra às drogas" e a criminalização da pobreza são elementos situados no âmbito político e ideológico, se materializam na luta de classes e são utilizados para o controle social. Mostramos a partir de alguns trechos de sentenças judiciais e manifestação do Ministério Público, o quanto os discursos ideologizados justificam a criminalização de adolescentes pobres por tráfico de drogas, colocando‑os como inimigos sociais sem considerar as contradições e riscos que são...

  19. Proibicionismo e a criminalização de adolescentes pobres por tráfico de drogas

    OpenAIRE

    Rocha, Andréa Pires

    2013-01-01

    O proibicionismo, a "guerra às drogas" e a criminalização da pobreza são elementos situados no âmbito político e ideológico, se materializam na luta de classes e são utilizados para o controle social. Mostramos a partir de alguns trechos de sentenças judiciais e manifestação do Ministério Público, o quanto os discursos ideologizados justificam a criminalização de adolescentes pobres por tráfico de drogas, colocando‑os como inimigos sociais sem considerar as contradições e riscos que são subme...

  20. Definición de alta hospitalaria, lesión grave y muerte por lesiones por tráfico

    Directory of Open Access Journals (Sweden)

    Katherine Pérez

    2014-05-01

    Full Text Available La vigilancia de las lesiones producidas por tráfico comporta numerosas dificultades metodológicas debido, entre otras razones, a la falta de criterios consensuados de definición de caso. Para monitorizar las lesiones por tráfico, habitualmente se han utilizado los registros policiales como fuente principal de información, y en cambio apenas se han utilizado fuentes sanitarias. La fuente de origen policial suele disponer de información exhaustiva sobre las características de la colisión, pero en general infranotifica casos y no recoge información fiable sobre la gravedad de las lesiones. Aun así, las estadísticas de heridos graves se han basado casi exclusivamente en criterios policiales. Esta nota tiene como objetivo proponer criterios para definir, a partir de fuentes sanitarias: a «Alta hospitalaria por lesiones por tráfico», b «Persona con lesión grave por tráfico», y c «Muerte por lesiones por tráfico», con la finalidad de homogeneizar el uso de estas fuentes.

  1. Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway.

    Science.gov (United States)

    Gregori, Silvia; Tomasoni, Daniela; Pacciani, Valentina; Scirpoli, Miriam; Battaglia, Manuela; Magnani, Chiara Francesca; Hauben, Ehud; Roncarolo, Maria-Grazia

    2010-08-12

    Type 1 T regulatory (Tr1) cells suppress immune responses in vivo and in vitro and play a key role in maintaining tolerance to self- and non-self-antigens. Interleukin-10 (IL-10) is the crucial driving factor for Tr1 cell differentiation, but the molecular mechanisms underlying this induction remain unknown. We identified and characterized a subset of IL-10-producing human dendritic cells (DCs), termed DC-10, which are present in vivo and can be induced in vitro in the presence of IL-10. DC-10 are CD14(+), CD16(+), CD11c(+), CD11b(+), HLA-DR(+), CD83(+), CD1a(-), CD1c(-), express the Ig-like transcripts (ILTs) ILT2, ILT3, ILT4, and HLA-G antigen, display high levels of CD40 and CD86, and up-regulate CD80 after differentiation in vitro. DC-10 isolated from peripheral blood or generated in vitro are potent inducers of antigen-specific IL-10-producing Tr1 cells. Induction of Tr1 cells by DC-10 is IL-10-dependent and requires the ILT4/HLA-G signaling pathway. Our data indicate that DC-10 represents a novel subset of tolerogenic DCs, which secrete high levels of IL-10, express ILT4 and HLA-G, and have the specific function to induce Tr1 cells.

  2. Acidentes de trânsito: uma visão qualitativa no Município de Campinas, São Paulo, Brasil

    Directory of Open Access Journals (Sweden)

    Marcos S. Queiroz

    2002-10-01

    Full Text Available Este artigo focaliza, numa perspectiva interdisciplinar qualitativa, o problema de acidentes de trânsito no Município de Campinas. Ele começa analisando o processo de municipalização do transporte e trânsito no município, com base nas representações sociais de técnicos da Secretaria Municipal de Transporte. Alguns números são trazidos à tona para mostrar uma queda significativa de mortes no trânsito em Campinas nos últimos dez anos. Esses números demonstram que as políticas públicas implementadas nesse setor têm sido positivas em vários aspectos. Atenção especial é dada aos objetivos, estratégias e obstáculos encontrados pelo poder local no processo de municipalização do trânsito. O artigo conclui enfatizando que, além da municipalização, o Estado necessita implementar políticas públicas específicas consistentes, principalmente aquelas voltadas à revitalização do transporte coletivo e a programas de educação no trânsito, a fim de se poder avançar no controle do problema.

  3. Banco de sementes do solo em três fases sucessionais de uma Floresta Estacional Decidual em Santa Tereza, RS.

    Directory of Open Access Journals (Sweden)

    Solon Jonas Longhi

    2010-08-01

    Full Text Available Com o objetivo de avaliar o banco de sementes no solo e compreender aspectos da dinâmica sucessional de Floresta Estacional Decidual, foram coletadas 60 amostras de 1 m2 no final de cada estação do ano, em três estágios sucessionais (Capoeirão, Floresta Secundária e Floresta Madura. Em cada ponto amostral, foi coletado o folhedo e os primeiros 3 cm de solo. No Centro Tecnológico de Silvicultura da UFSM o material foi posto para germinar, separadamente, em canteiros de madeira de 1 m2, que continham 5 cm de solo de horizonte B como substrato. Os canteiros foram cobertos com sombrite de 50% de sombreamento para o Capoeirão, 70% para a Floresta Secundária e 80% para a Floresta Madura. Foram feitas avaliações qualitativas e quantitativas, por espécie e unidade amostral, 20 dias após a instalação no viveiro e posteriormente a cada 30 dias. Foram calculadas a freqüência e densidade relativas e o Índice de Diversidade de Shannon. Encontraram-se 216 indivíduos, sendo a maioria deles na Floresta Madura, a qual também apresentou a maior riqueza florística. Nas três subseres, houve predominância de espécies secundárias iniciais. A estação de primavera apresentou a maior abundância de espécies, porém, no verão ocorreu a maior densidade de indivíduos por área.

  4. Saúde, Religião e Trânsito Religioso: Estudo Pró-Saúde

    Directory of Open Access Journals (Sweden)

    Ana Paula Nunes

    Full Text Available RESUMO Embora pesquisas qualitativas apontem para uma relação entre mudança de religião e busca por saúde e superação de doenças e do sofrimento em geral, há pouca produção de dados quantitativos sobre o tema. Esse artigo pretende preencher em parte essa lacuna analisando os resultados de um estudo epidemiológico com funcionários públicos no Rio de Janeiro (Estudo Pró-Saúde em 1999. Dos 3.562 indivíduos pesquisados, 62% mantiveram a religião em que foram criados, 26% mudaram de religião, e 12% mudaram para “sem religião”. O trânsito religioso, variável derivada da comparação entre religião de criação e religião declarada à época da pesquisa, foi marcado por crescimento de kardecistas e do grupo “sem religião”. Para verificar a associação entre a variável autopercepção da saúde e as variáveis identidade religiosa e trânsito religioso, foi realizada uma análise estatística ajustada por variáveis sociais e demográficas. Observou-se uma chance 40% mais elevada de uma autopercepção da saúde “regular ou ruim” estar associada à mudança de religião, quando comparada à autopercepção de saúde “boa ou muito boa”, independentemente de idade, sexo e escolaridade.

  5. FTIR spectroscopy as an alternative tool for high gamma dose dosimetry using P(VDF-TrFE) fluorinated copolymers

    International Nuclear Information System (INIS)

    Medeiros, Adriana S.; Liz, Otavio S.

    2011-01-01

    Poly(vinylidene fluoride) [PVDF] is a semicrystalline homopolymer and some of its fluorinated copolymer has demonstrated to have sensitiveness to high doses of ionizing radiation. We have recently proposed a semicrystalline fluorinated PVDF copolymer, the poly(vinylidene-trifluorethylene) [P(VDF-TrFE], as a candidate for measuring larger dose ranges. In fact, in these copolymers the optical absorption peak at 274 nm has been used to measure gamma doses ranging from 1.0 to 100.0 kGy and the melting latent heat, collected by differential scanning calorimetry (DSC), have been used to measure gamma doses from 1.0 to 1,000.0 kGy. In this paper, the infrared stretching vibration of radio-induced in-chain unsaturations (CH=CF) in P(VDF-TrFE) copolymers has been considered as an alternative tool for high dose dosimetric purposes. FTIR spectroscopic data revealed two optical absorption bands at 1754 cm -1 and 1854 cm -1 whose intensities are unambiguously related to gamma delivered doses ranging from 100.0 kGy to 1,000.0 kGy. Fading was evaluated one month after irradiation. The results indicate that the sample dose evaluation should be performed in the first two hours after being exposed to the radiation beam. The radio-induced formation of unsaturations was also investigated by ultraviolet and visible spectroscopy, which has confirmed the gradual increase of conjugated C=C bonds with the absorbed dose. Our results indicate that quantitative analysis of FTIR absorption bands is a useful tool to perform a product end-point dosimetry in radiation processing facilities that use high gamma dose irradiation. (author)

  6. Aspectos sociodemográficos associados a três comportamentos sedentários em trabalhadores brasileiros

    Directory of Open Access Journals (Sweden)

    Leandro Martin Totaro Garcia

    2015-05-01

    Full Text Available O objetivo foi investigar a associação entre aspectos sociodemográficos e três comportamentos sedentários em trabalhadores da indústria no Brasil. Analisaram-se dados de 47.477 trabalhadores das indústrias de 24 Unidades Federativas, coletados por questionário de 2006 a 2008. Analisou-se a presença individual e simultânea de assistência à televisão ≥ 4 horas/dia, deslocamento de carro ou moto para o trabalho e passar a maior parte do tempo sentado no trabalho, assim como a associação desses comportamentos sedentários com sexo, idade, renda familiar mensal e nível de escolarização. Para tanto, utilizou-se a regressão logística binária simples e múltipla. Trabalhadores com mais idade, escolarização e renda tiveram maiores odds de apresentar dois dos três comportamentos sedentários investigados, assim como a presença simultânea deles. As associações entre sexo e comportamentos sedentários dependem do comportamento investigado. Tais informações podem ajudar no planejamento de ações de redução de comportamentos sedentários mais bem direcionadas e mais eficientes no alcance de diferentes subgrupos da população.

  7. Adsorção e lixiviação de tebuthiuron em três tipos de solo

    Directory of Open Access Journals (Sweden)

    M. Dornelas De Souza

    2001-12-01

    Full Text Available Estudou-se a adsorção do herbicida tebuthiuron em três solos de Ribeirão Preto (SP: Latossolo Vermelho distrófico (LVd, Latossolo Vermelho distroférrico (LVdf e Neossolo Quartzarênico (RQ. Ajustaram-se isotermas de adsorção por meio de quatro modelos: linear, Freundlich, Lambert e Langmuir, para duas profundidades: 0-10 cm e 10-20 cm. Nos três tipos de solo, o melhor ajuste foi obtido com o modelo de Freundlich, escolhido com base nos seguintes critérios estatísticos: quadrado do coeficiente de correlação entre valores observados e preditos (R², quadrado médio do erro (QME, dispersão de resíduos padronizados e gráficos de probabilidade normal. Os coeficientes de partição do herbicida calculados com base em todo o solo (Kd ou com base no seu teor de carbono orgânico (K OC ou de matéria orgânica (K OM variaram de 0,723 a 2,573; de 135,4 a 374,3 e de 78,4 a 218,3 L kg-1, respectivamente, tendo ocorrido correlação significativa entre os valores de Kd e teor de carbono orgânico dos solos e teor de argila. Efetuou-se um teste de lixiviação em colunas, no qual se observou movimento do herbicida até à profundidade de 60 cm no RQ, 20 cm no LVd e 10 cm no LVdf, verificando-se uma relação inversa entre a profundidade alcançada pelo produto e o valor de Kf de Freundlich utilizado como estimador de Kd.

  8. Judicialização da Saúde: um estudo de caso de três tribunais brasileiros

    Directory of Open Access Journals (Sweden)

    Denise Vieira Travassos

    2013-11-01

    Full Text Available O objetivo deste trabalho foi descrever e comparar registros de três tribunais brasileiros quanto às características e resultados das ações relacionadas ao Sistema Único de Saúde (SUS. Foi realizada pesquisa dos acórdãos nos sítios eletrônicos dos Tribunais de Justiça dos estados de Pernambuco, Rio Grande do Sul e Minas Gerais, utilizando-se roteiro próprio. Analisou-se 558 acórdãos. Houve maior frequência de ações ordinárias (73,1%, na maior parte das decisões não foi possível verificar a situação econômico-financeira do demandante e o representante do autor (69,1% e 54,5% Nas que foram possíveis, a defensoria pública foi mais frequente (71,5, principalmente no Rio Grande do Sul (90,2%. A titularidade das ações foi predominantemente individual nos três grupos. Houve grande número de pedidos liminares (83,8%, quase sempre deferidos (91,2%, com alegação de urgência/emergência em quase todos (98,8%. A maioria das decisões foi favorável aos usuários (97,8%. As decisões estudadas demonstraram que o usuário tem buscado de forma individual garantir seu direito à saúde, recorrendo ao próprio poder público para a propositura da ação, mas percebe-se uma diferença de postura jurídica entre os tribunais avaliados. Há uma forte tendência do Judiciário em acolher estas solicitações.

  9. Evidence of Tamarix hybrids in South Africa, as inferred by nuclear ITS and plastid trnS-trnG DNA sequences

    Science.gov (United States)

    Tamarix usneoides (Tamaricaceae) is a species native to southern Africa where it is currently being used in the mines for phytoremediation. However, Tamarix aphylla, T. ramosissima, T. chinensis, and T. parviflora have been reported as exotic species in South Africa, with T. ramosissima declared inv...

  10. trné podmínky pro malé větrné elektrárny

    Czech Academy of Sciences Publication Activity Database

    Hanslian, David

    -, červen (2012), - ISSN 1801-4399 R&D Projects: GA AV ČR(CZ) KJB300420905 Institutional support: RVO:68378289 Keywords : wind energy * small wind turbines * wind speed * wind conditions * wind power production Subject RIV: DG - Athmosphere Sciences, Meteorology http://oze.tzb-info.cz/vetrna-energie/8358-vetrne-podminky-pro-male-vetrne-elektrarny

  11. Tráfego veicular e mortalidade por doenças do aparelho circulatório em homens adultos

    OpenAIRE

    Habermann, Mateus; Gouveia, Nelson

    2011-01-01

    OBJETIVO: Analisar a associação entre indicadores de exposição à poluição por tráfego veicular e mortalidade por doenças do aparelho circulatório em homens adultos. MÉTODOS: Foram analisadas informações sobre vias e volume de tráfego no ano de 2007 fornecidas pela companhia de engenharia de tráfego local. Mortalidade por doenças do aparelho circulatório no ano de 2005 entre homens > 40 anos foram obtidas do registro de mortalidade do Programa de Aprimoramento de Informações de Mortalidade do ...

  12. O planejamento urbano e os acidentes de trânsito: um estudo sobre o Município de Toledo - PR

    OpenAIRE

    Ruschel, Andressa Carolina

    2017-01-01

    O artigo propõe identificar como o planejamento urbano influencia nos acidentes de trânsito no Município de Toledo - PR no período de 2011 a 2015, dentro do Perímetro Urbano, partindo da problematização criada pelo alto índice de acidentes de trânsito no município. A metodologia utilizada foi através de aspectos conceituais da análise espacial e do planejamento urbano; coleta de dados primários nos Boletins de Ocorrência de Acidentes de Trânsito, em seguida tabelados e analisados conforme fun...

  13. A violência no trânsito : um estudo de cado do PVT - Recife/PE 2000-2004

    OpenAIRE

    de Sá Gondim, Getúlio

    2004-01-01

    A violência no trânsito tem se constituído em uma séria problemática para todos, cuja solução deve ser tratada no âmbito das políticas públicas. Este Trabalho de Conclusão de Mestrado teve como objeto de análise a violência no trânsito na cidade do Recife, no período de 2000 a 2004. Definiu como objetivo analisar se o Projeto Vida no Trânsito contribuiu para reduzir os índices de acidentes, a multiinstitucionalidade e a ação educativa conscientizadora por meio dos arte-educadores. A metodolog...

  14. Retos tecnológicos para medir el tráfico en Bogotá mediante GPS y comunicación celular

    Directory of Open Access Journals (Sweden)

    Germán Bravo C.

    2013-08-01

    Full Text Available El Sistema de Información de Tráfico y Movilidad Urbana (SITYMUR es una herramienta que busca recolectar información proveniente de agentes que circulan en las vías, con el fin de obtener información del tráfico y de la movilidad en un tiempo cercano al real. Lograr este resultado plantea retos tecnológicos importantes, tanto de comunicaciones como de procesamiento de los datos y publicación de los resultados. El artículo describe estos retos y discute la efectividad de las soluciones planteadas para cada uno mostrando algunos resultados de tráfico y de velocidad para Bogotá y posibles alternativas de mejora.

  15. Simulação de controle adaptativo de tráfego urbano por meio de sistema multiagentes e com base em dados reais

    Directory of Open Access Journals (Sweden)

    Gilberto Dessbesell Junior

    2015-11-01

    Full Text Available A população urbana cresce rapidamente e a quantidade de veículos, mais rápido ainda. Esse crescimento satura a infraestrutura de transportes, gerando lentidão, congestionamentos e aumentando o tempo das viagens. Os engarrafamentos têm causado transtornos econômicos, sociais e ambientais. Com o aumento do tempo das viagens e da quantidade de veículos nas ruas, aumentam também a poluição sonora e do ar. Além disso, diariamente os condutores enfrentam situações de estresse no trânsito. Melhorias nos sistemas de controle de tráfego têm sido propostas, mesmo assim ainda há muito a ser feito. Neste trabalho foi verificada a eficácia do emprego de agentes inteligentes para o controle do tráfego urbano, em ambiente de simulação multiagentes, a fim de reduzir os efeitos negativos dos congestionamentos. Foi utilizado o simulador de tráfego urbano SUMO para realizar a simulação do tráfego de veículos em uma região de Porto Alegre, RS. Dados reais a respeito da programação dos semáforos e do volume de tráfego foram utilizados. Após, foi desenvolvido um semáforo inteligente, que utiliza uma heurística para tomar suas decisões e a simulação foi realizada novamente. O resultado das duas simulações foi, então, comparado e os resultados encontrados foram considerados de grande relevância.

  16. SAG/ROC-SCFβ-TrCP E3 Ubiquitin Ligase Promotes Pro-Caspase-3 Degradation as a Mechanism of Apoptosis Protection

    Directory of Open Access Journals (Sweden)

    Mingjia Tan

    2006-12-01

    Full Text Available Skp1-cullin-F-box protein (SCF is a multicomponent E3 ubiquitin (Ub ligase that ubiquitinates a number of important biologic molecules such as p27, β-catenin, and lκB for proteasomal degradation, thus regulating cell proliferation and survival. One SCF component, SAG/ROC2/Rbx2/Hrt2, a RING finger protein, was first identified as a redox-inducible protein, which, when overexpressed, inhibited apoptosis both in vitro and in vivo. We report here that sensitive to apoptosis gene (SAG, as well as its family member ROC1/Rbxi, bound to the proinactive form of caspase-3 (pro-caspase-3. Binding was likely mediated through F-box protein, β-transducin repeat-containing protein (β-TrCP, which binds to the first 38 amino acids of pro-caspase-3. Importantly, β-TrCP1 expression significantly shortened the protein half-life of pro-caspase-3, whereas expression of a dominant-negative β-TrCP1 mutant with the F-box domain deleted extended it. An in vitro ubiquitination assay showed that SAG/ROC-SCF -Trcp promoted ubiquitination of pro-caspase-3. Furthermore, endogenous levels of pro-caspase-3 were decreased by overexpression of SAG/ROC-SCFβ-TrCP E3 Ub ligases, but increased on siRNA silencing of SAG, regulator of cullin-1 (ROC1, or β-TrCPs, leading to increased apoptosis by etoposide and TNF-related apoptosis-inducing ligand through increased activation of caspase-3. Thus, pro-caspase-3 appears to be a substrate of SAG/ROC-SCFβ-TrCP E3 Ub ligase, which protects cells from apoptosis through increased apoptosis threshold by reducing the basal level of pro-caspase-3.

  17. [Development of noninvasive bladder cancer diagnosis on basis of telomerase and it's subunits hTERT and hTR detection].

    Science.gov (United States)

    Glukhov, A I; Grigorieva, Y E; Gordeev, S A; Vinarov, A Z; Potoldykova, N V

    2015-01-01

    Telomerase activity (TA) and expression of genes coding it's subunits (hTERT and hTR) have been examined in tumor tissue and urine sediment samples taken from patients with bladder cancer (BC) using the modified TRAP assay (in the case of telomerase detection) and RT-PCR (in the case of hTERT and hTR expression). Results obtained in this study demonstrate possibility of noninvasive diagnosis of BC with sensitivity of 96% and specificity of 100% in the case of telomerase detection and with sensitivity of 80% and specificity of 100% in the case of hTERT detection in urine sediment samples.

  18. Recopilación de las principales herramientas e indicadores en la relación tráfico-emisiones

    OpenAIRE

    Agüera Garre, David

    2017-01-01

    Recopilar y analizar todas las herramientas e indicadores utilizados para conocer la relación entre tráfico rodado en las ciudades y las emisiones de CO2. Con el presente estudio se ha pretendido dar un enfoque general acerca de un tema de vital importancia en la salud y que en contraposición está muy poco desarrollado en la mayoría del mundo, como es la contaminación generada por las emisiones del tráfico rodado. La mejor manera para controlar y poner medidas que contrarresten estas emisione...

  19. Expression and biological-clinical significance of hTR, hTERT and CKS2 in washing fluids of patients with bladder cancer

    Directory of Open Access Journals (Sweden)

    Talesa Vincenzo N

    2010-10-01

    Full Text Available Abstract Background at present, pathogenesis of bladder cancer (BC has not been fully elucidated. Aim of this study is to investigate the role of human telomerase RNA (hTR, human telomerase reverse transcriptase (hTERT and CDC28 protein kinase regulatory subunit 2 (CKS2 in bladder carcinogenesis and their possible clinical significance; Methods the transcript levels of hTR, hTERT and CKS2 were quantified by Real time reverse transcriptase chain reaction in exfoliated cells from bladder washings of 36 patients with BC and 58 controls. The statistical significance of differences between BC bearing patients and control groups, in the general as well as in the stratified analysis (superficial or invasive BC, was assessed by Student's t test. Non parametric Receiver Operating Characteristics analysis (ROC was performed to ascertain the accuracy of study variables to discriminate between BC and controls. The clinical value of concomitant examination of hTR, hTERT and CKS2 was evaluated by logistic regression analysis; Results a significant decrease in hTR and a significant increase in hTERT or CKS2 gene expression were found between BC bearing patients and controls, as well as in the subgroups analysis. The area under the curve (AUC indicated an average discrimination power for the three genes, both in the general and subgroups analysis, when singularly considered. The ability to significantly discriminate between superficial and invasive BC was observed only for hTR transcript levels. A combined model including hTR and CKS2 was the best one in BC diagnosis; Conclusions our results, obtained from a sample set particularly rich of exfoliated cells, provide further molecular evidence on the involvement of hTR, hTERT and CKS2 gene expression in BC carcinogenesis. In particular, while hTERT and CKS2 gene expression seems to have a major involvement in the early stages of the disease, hTR gene expression, seems to be more involved in progression. In

  20. Activity of Tedizolid Phosphate (TR-701) in Murine Models of Infection with Penicillin-Resistant and Penicillin-Sensitive Streptococcus pneumoniae

    OpenAIRE

    Choi, Sunghak; Im, Weonbin; Bartizal, Ken

    2012-01-01

    The in vitro activity of tedizolid (previously known as torezolid, TR-700) against penicillin-resistant Streptococcus pneumoniae (PRSP) clinical isolates and the in vivo efficacy of tedizolid phosphate (torezolid phosphate, TR-701) in murine models of PRSP systemic infection and penicillin-susceptible S. pneumoniae (PSSP) pneumonia were examined using linezolid as a comparator. The MIC90 against 28 PRSP isolates was 0.25 μg/ml for tedizolid, whereas it was 1 μg/ml for linezolid. In mice infec...

  1. Análisis del flujo de tráfico vehicular a través de un modelo macroscópico

    OpenAIRE

    Fernando Pérez; Alejandro Bautista; Martin Salazar; Antonio Macias

    2014-01-01

    Hoy en día la mayoría de las ciudades en el mundo se enfrentan a diversos problemas ocasionados por el tráfico vehicular debido al creciente número de vehículos en circulación, tales como congestionamiento, contaminación del medio ambiente, exceso de ruido, incremento del número de accidentes viales, etc. De ahí la importancia de representar el fenómeno de tráfico vehicular mediante modelos en busca de mejores patrones de flujo vehicular en una determinada ciudad. En este trabajo introducimos...

  2. Fatores de risco para mortalidade por doenças cardiovasculares associados à alta exposição ao tráfego veicular

    Directory of Open Access Journals (Sweden)

    Poliany Cristiny de Oliveira Rodrigues

    Full Text Available RESUMO: Objetivo: Identificar áreas e fatores de risco para a mortalidade causada por doenças cardiovasculares (DC associados à poluição do ar proveniente da alta exposição ao tráfego. Métodos: Estudo transversal da mortalidade por DC em 2.617 indivíduos de 45 a 85 anos residentes na zona urbana de Cuiabá e Várzea Grande, Mato Grosso, entre 2009 e 2011. Utilizou-se a proximidade residencial de até 150 metros de uma via de grande fluxo de veículos como proxy da alta exposição à poluição atmosférica proveniente do tráfego. A associação entre idade, sexo, renda e intensidade do trânsito com a exposição ao tráfego foi avaliada por meio de regressão logística múltipla. Foram realizadas análises estratificadas para observar a influência das estações do ano e dos grupos de causas. Utilizou-se modelo espacial de probabilidade de Bernoulli para identificação de áreas de risco. Resultados: Os principais fatores de risco para mortalidade por DC associados à alta exposição ao tráfego foram: residir em setores censitários com renda muito desigual (OR = 1,78; IC95% 1,36 - 2,33, trânsito intenso (OR = 1,20; IC95% 1,01 - 1,43 e sexo feminino (OR = 1,18; IC95% 1,01 - 1,38. O risco de mortalidade por DC aumenta cerca de 10% no período de seca. Foram identificadas nove áreas de risco. Conclusão: A alta exposição ao tráfego está associada à mortalidade por DC em Cuiabá e Várzea Grande. A desigualdade de renda, a intensidade do trânsito e o sexo feminino apresentaram-se como os principais determinantes dessa exposição, além da estação seca potencializá-la.

  3. Modelo de Detección de Datos Atípicos de Tráfico. Autopista C-58, Barcelona

    OpenAIRE

    Ahumada Valenzuela, Pamela

    2011-01-01

    Desde al año 2009, en la autopista C-31 y C32, pertenecientes a los accesos sur de la ciudad de Barcelona, comienzan a operar con una nueva modalidad en la gestión de tráfico, con “Velocidad Variable”. Dicho límite de velocidad se establece por medio de un algoritmo, el que es alimentado por diferentes variables, entre ellas, la información aportada los medios electrónicos instalados en dichas autopistas, los detectores. A partir de esta incorporación en la gestión de tráfico de carreteras...

  4. Integração das artes na obra de Oscar Niemeyer : três espaços consagrados em Brasília

    OpenAIRE

    Lima, Elizabeth Ervatti Rocha de

    2014-01-01

    A pesquisa consiste na abordagem da temática relacional entre as artes plásticas e a arquitetura moderna brasileira. Para tanto, seleciona-se três obras de arquitetura religiosa projetadas pelo arquiteto Oscar Niemeyer em Brasília, sendo elas: Capela Nossa Senhora da Alvorada (1957-1958), Capela Nossa Senhora de Fátima (1957-1958) e a Catedral Metropolitana Nossa Senhora Aparecida (1958-1989). Sob estes três espaços consagrados verifica-se a problemática da ocorrência de integração ou ...

  5. Tráfico, contrabando e imigração irregular: os novos contornos da imigração brasileira em Portugal

    OpenAIRE

    Peixoto, João

    2007-01-01

    Neste texto são apresentados alguns problemas conceptuais sobre “tráfico” e “contrabando” de migrantes, dados sobre a imigração brasileira recente e elementos sobre a actuação das redes organizadas de contrabando de migrantes e tráfico de mulheres para fins de exploração sexual do Brasil para Portugal. O aumento de importância das redes organizadas e o fortalecimento dos negócios relacionados com a indústria do sexo estão entre as principais conclusões. O apoio em redes sociais informais e gr...

  6. Responsabilidad por daños en accidentes de tráfico causados por especies cinegéticas : evolución y jurisprudencia

    OpenAIRE

    Troiteiro Rodriguez, Daniel

    2016-01-01

    Del total de accidentes de tráfico que tienen lugar en España, el 7% corresponde a siniestros contra objetos o animales. Siendo las especies cinegéticas (sobretodo jabalíes, corzos y ciervos) las que más número de accidentes causan, alrededor del 60%. Siendo éste el panorama, el objetivo que me planteo en este trabajo es estudiar y analizar la responsabilidad derivada de los accidentes de tráfico causados por animales, concretamente por especies cinegéticas. Y no solo la responsabilidad en té...

  7. Enginyeria de tràfic en xarxes de transport òptiques per a entorns d'àrea metropolitana (RPR) i de gran abast (ASON)

    OpenAIRE

    Spadaro, Salvatore

    2005-01-01

    La arquitectura de las redes de transporte actuales está basada en la tecnología de transporte SDH (Synchronous Digital Hierarchy). Las redes SDH se han diseñado y están optimizadas básicamente para el transporte del tráfico de voz. Actualmente, se está experimentando un crecimiento exponencial del volumen de tráfico de datos. Este crecimiento se debe a que el protocolo IP se está consolidando como capa de integración para servicios múltiples, algunos de ellos con requerimientos de Calidad de...

  8. Rendimiento del pasto ballico perenne (Lolium perenne L.) y ovillo (Dactylis glomerata L.) solos y asociados con trébol blanco (Trifolium repens L.).

    OpenAIRE

    Mendoza Pedroza, Sergio Iban

    2014-01-01

    El objetivo del estudio fue evaluar la respuesta productiva de los pastos ballico perenne y ovillo solos y asociados con trébol blanco en las siguientes proporciones: 100:00:00, 00:100:00, 70:20:10, 00:50:50, 50:00:50, 40:40:20 40:20:40, 20:70:10 y 20:40:40 % de ballico perenne, ovillo y trébol blanco (BP:O:TB), mismas que se distribuyeron aleatoriamente en 27 unidades experimentales bajo un diseño de bloques completos al azar con tres repeticiones. Se determinó el rendimiento de forraje, com...

  9. Los movimientos migratorios y la nueva configuración del tráfico externo (The Migratory Movements and the New Configuration of the International Private Relationships)

    OpenAIRE

    Fernández Rozas, José Carlos

    1987-01-01

    I. La inicidencia de los factores demográficos en la reglamentación del tráfico externo. 1. El protagonismo de los particulares en las relaciones privadas internacionales. 2. Los movimientos migratorios como condicionante de la reglamentación del tráfico externo. II. Movimientos migratorios y territorialidad. 1. Intereses de política legislativa. 2. La dialéctica entre el ius soli y el ius sanguinis. 3. La dialéctica entre la ley nacional y la ley del domicilio. III. Movimientos migratorios y...

  10. Oasis: Uso de escáneres láser en infraestructuras ITS para modelización del tráfico

    OpenAIRE

    Sastre García, Daniel; Badillo Lopez, Mercedes; Menendez Garcia, Jose Manuel

    2010-01-01

    Detectar, predecir y gestionar el tráfico a lo largo de una autopista con herramientas inteligentes lo más automatizadas posibles y con el fin de obtener un tráfico uniforme, es uno de los principales objetivos del proyecto CENIT OASIS (Operación de autopistas seguras inteligentes y sostenibles). Dentro del ámbito de la movilidad, es fundamental establecer un modelo de sensorización óptimo que extraiga la máxima información y de la mayor calidad posible. Para ello, la visión artificial...

  11. Cambios en la ecología trófica de los depredadores apicales del Mar Argentino durante el Holoceno

    OpenAIRE

    Saporiti, Fabiana

    2014-01-01

    [spa] El Mar Argentino ha sufrido un impacto humano creciente desde el Holoceno medio hasta hoy en día, fruto del cual se han producido importantes cambios en los niveles más altos de la red trófica. Las actividades extractivas (caza y pesca), tanto la aborigen como la actual, tienen la tendencia a explotar las especies de mayor tamaño, produciendo el efecto conocido en gestión de pesquerías como “fishing down the food web”. En otras palabras el impacto humano llevaría a cadenas tróficas más ...

  12. O pulo do gato preto: estudo de três dimensões educacionais das artes-caminhos marciais em uma linhagem de capoeira angola

    OpenAIRE

    Fabio José Cardias Gomes

    2012-01-01

    O presente trabalho objetivou compreender três dimensões educativas marciais a partir da trajetória de pessoas praticantes formadas mestre e contramestre na linhagem de capoeira angola de Mestre Gato Preto. Além da revisão da literatura sobre os estudos teóricos da capoeira realizou-se entrevista de histórias de vida, iniciou-se a construção da biografia de Mestre Gato e sua escola de capoeira, sistematizou-se três dimensões educativas das artes marciais esparsas na literatura, relacionou-se ...

  13. Estructura de la comunidad de moluscos y relaciones tróficas en el litoral rocoso del estado Sucre, Venezuela

    Directory of Open Access Journals (Sweden)

    Johanna Fernández

    2006-12-01

    Full Text Available Se analizó la estructura de la comunidad de moluscos y sus relaciones tróficas en seis localidades del litoral rocoso con diferentes grados de exposición al oleaje (área expuesta y área protegida, en el Estado Sucre, Venezuela. El muestreo se llevó a cabo durante el período de marzo 2003 a febrero 2004. La recolección del material biológico se realizó de forma manual con ayuda de una espátula, dentro de una cuadrícula de 0.25 m², estableciéndose tres zonas: supra, medio e infralitoral. Los organismos fueron preservados en frascos con formalina al 10% para su posterior análisis. En el laboratorio fueron identificados, contados, y pesados en una balanza de 0.001g de precisión. Se determinó la abundancia total de especies, biomasa, constancia específica y por medio de una revisión bibliográfica se le asignó a cada especie su categoría trófica, clasificándolos en: herbívoros, filtradores, carnívoros y herbívoros -filtradores. Se obtuvo un total de 14 581 individuos (6 397.945 g representado por 68 especies correspondientes a las clases Gastropoda (39, Bivalvia (23 y Polyplacophora (6; contenidas en nueve órdenes y 31 familias. Los herbívoros fueron el grupo dominante (49%, seguido por filtradores (37%, carnívoros (13 % y herbívoros-filtradores (1%. Las especies herbívoras y herbívoras-filtradoras dominaron en el área protegida, mientras que en el área expuesta, fueron las carnívoras y filtradoras. Las especies constantes en las seis localidades durante el período de estudio fueron Planaxis nucleus, Mitrella ocellata, M. nycteis, Littorina interrupta, Tegula fasciata, Acmaea leucopleura, Ostrea equestris y Chiton squamosus. La distribución de los moluscos y los diferentes grupos tróficos, pueden estar controlados por adaptaciones morfológicas, así como el nivel de exposición al oleaje y composición del sustrato.Mollusc community structure and trophic relations in the rochy littoral zone in Sucre State

  14. Avaliação do estado trófico do Reservatório Lago do Amor (Campo Grande, MS) através da aplicação de sensoriamento remoto

    OpenAIRE

    Coelho, Luiza Spengler

    2010-01-01

    Dois artigos são apresentados. O primeiro é intitulado: Classificação trófica de reservatórios utilizando índices de estado trófico: estudo de caso do reservatório tropical raso Lago do Amor; e o segundo: Uso do Sensor CBERS/CCD na avaliação do estado trófico do reservatório Lago do Amor. O primeiro objetivou estimar o estado trófico do “Lago do Amor” através da aplicação do índice de estado trófico modificado por Toledo (1990) e índice de estado trófico de Lamparelli (2004), usando dados do ...

  15. Estudo de caso de três espécies de plantas bioindicadoras de solos salinos

    Directory of Open Access Journals (Sweden)

    Mercia Fonseca Carvalho

    2015-07-01

    Full Text Available Bioindicadores, de uma maneira geral, são seres vivos de natureza diversa, vegetais ou animais, utilizados para analisar a qualidade de um determinado ambiente. A degradação ambiental do solo pela salinidade é um problema muito antigo e de extensão mundial, geralmente, mais pronunciado nas regiões áridas e semi-áridas. As plantas que se desenvolvem em áreas com elevadas concentrações de sais são chamadas de halófitas, e algumas delas são usadas na recuperar desses solos. O objetivo desse trabalho é analisar três espécies de plantas resistentes ao estresse salino gerar recomendações a respeito das mesmas, disponibilizando uma indicação de espécie que possa recuperar o ambiente salinizado. Foram selecionadas aleatoriamente três espécies de plantas resistentes a salinidade Copernicia prunifera, Atriplex nummularia L. e Gossypium hirsutum L, as mesmas foram analisados por uma planilha com características que identificam um bioindicador ideal e em seguida as espécies foram avaliadas de acordo com sua fisiologia e etiologia. Embora as propriedades da espécie A. nummularia tenha se destacado por recuperar os solos salinizados a espécie Copernicia prunifera foi considerada como um bioindicador ideal. Recomendam-se ainda estudos mais aprofundados acerca desse assunto.Case study of three species of saline soil bioindicatorsAbstract: Bioindicators, in general, living organisms are diverse in nature, plant or animal used to assess the quality of a given environment. Environmental degradation by soil salinity is a very old problem and expanse world generally more pronounced in arid and semi-arid regions. Plants that thrive in areas with high concentrations of salts are called halophytes, and some of them are used in recovering these soils. The aim of this work is to analyze three species of plants resistant to salt stress generate recommendations regarding the same, providing an indication of species that can restore the

  16. Lesiones relacionadas con el tráfico y papel de los centros de reconocimiento de conductores

    Directory of Open Access Journals (Sweden)

    Julio Pérez de la Paz

    2014-01-01

    Full Text Available Las lesiones derivadas de los accidentes de tráfico suponen un importante problema de Salud Pública cuyo abordaje ha variado en los últimos tiempos gracias a un enfoque científico que ha permitido tratarlos también desde la perspectiva de la prevención. Los datos de siniestralidad que aporta la Dirección General de Tráfico permiten estudiar el fenómeno desde el punto de vista epidemiológico. Las cifras de fallecidos y heridos graves presentan una disminución progresiva en los últimos años que nos sitúan en 7.º lugar en cuanto a fallecidos en la Unión Europea. Las lesiones más frecuentes son las fracturas, predominado en miembros inferiores. El índice de gravedad MAIS 3+ indica que las personas de más edad son las que presentan mayor porcentaje de lesiones graves. El coste anual de las lesiones ronda el 1% del PIB. Los Centros de Reconocimiento de Conductores (CRC como tales comenzaron a funcionar en 1982 con el fin de valorar las aptitudes psicofísicas de los conductores. Son centros de carácter sanitario cuya última regulación normativa data de 2010, basándose para la valoración psicofísica de los conductores en el Anexo IV del Reglamento General de Conductores. Aparte de un protocolo básico aplicable a todos los conductores existe un protocolo específico para valorar determinadas alteraciones y factores de riesgo dirigido a conductores profesionales. Este modelo adolece de ciertas deficiencias que requiere una revisión que permita una mayor eficiencia en la detección y control del conductor de riesgo que implica avanzar en el proceso de colaboración entre los CRC y todos los agentes implicados a fin de mejorar la transferencia de información.

  17. O papel dos Pontos de Troca de Tráfego em políticas e regulação da banda larga

    Directory of Open Access Journals (Sweden)

    Daniel Brandão Cavalcanti

    2011-05-01

    Full Text Available Novos investimentos em infraestrutura de redes de transporte (backbones para a internet e a necessidade de trocar tráfego com backbones existentes, tanto na modalidade de trânsito como na de peering, indicam a crescente relevância de um elemento-chave nessa arquitetura – o Ponto de Troca de Tráfego (PTT. Há muito poucos PTT disponíveis hoje em dia, principalmente se considerado o vertiginoso crescimento no número de sistemas autônomos anunciados. Os PTT implantados por redes de pesquisa demonstram que um acréscimo expressivo no número desses pontos teria o efeito de melhorar a topologia da internet, aumentar a conectividade, reduzir a latência e o custo de troca de tráfego. Adicionalmente, os PTT podem ser o local mais eficiente para a oferta de determinados serviços. Este trabalho aborda as possibilidades de ação regulatória para estimular a implementação dos PTT e para assegurar que seus benefícios sejam amplamente compartilhados.

  18. Is the Eating Disorder Questionnaire-Online (EDQ-O) a valid diagnostic instrument for the DSM-IV-TR classification of eating disorders?

    NARCIS (Netherlands)

    Huurne, E.D. ter; Haan, H.A. de; Napel-Schutz, M.C. ten; Postel, M.G.; Menting, J.; Palen, J.A.M. van der; Vroling, M.S.; Jong, C.A.J. de

    2015-01-01

    Background: The Eating Disorder Questionnaire-Online (EDQ-O) is an online self-report questionnaire, which was developed specifically to provide a DSM-IV-TR classification of anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), and eating disorder not otherwise specified

  19. Is the Eating Disorder Questionnaire-Online (EDQ-O) a valid diagnostic instrument for the DSM-IV-TR classification of eating disorders?

    NARCIS (Netherlands)

    ter Huurne, Elke D.; de Haan, Hein A.; ten Napel-Schutz, Marieke C.; Postel, Marloes Gerda; Menting, Juliane; van der Palen, Jacobus Adrianus Maria; Vroling, Maartje S.; de Jong, Cor A.J.

    2015-01-01

    Background The Eating Disorder Questionnaire-Online (EDQ-O) is an online self-report questionnaire, which was developed specifically to provide a DSM-IV-TR classification of anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), and eating disorder not otherwise specified (EDNOS),

  20. Análisis del flujo de tráfico vehicular a través de un modelo macroscópico

    Directory of Open Access Journals (Sweden)

    Fernando Pérez

    2014-01-01

    Full Text Available Hoy en día la mayoría de las ciudades en el mundo se enfrentan a diversos problemas ocasionados por el tráfico vehicular debido al creciente número de vehículos en circulación, tales como congestionamiento, contaminación del medio ambiente, exceso de ruido, incremento del número de accidentes viales, etc. De ahí la importancia de representar el fenómeno de tráfico vehicular mediante modelos en busca de mejores patrones de flujo vehicular en una determinada ciudad. En este trabajo introducimos un modelo macroscópico simple para describir el flujo vehicular en un congestionamiento tráfico y obtenemos la ecuación que relaciona el comportamiento característico entre flujo vehicular y densidad de tráfico, conocida en la literatura como relación fundamental. Finalmente, hallamos una solución analítica para la fluidez óptima del paso de vehículos en un tramo de carretera congestionado.

  1. Diagnostic Classification of Eating Disorders in Children and Adolescents: How Does DSM-IV-TR Compare to Empirically-Derived Categories?

    Science.gov (United States)

    Eddy, Kamryn T.; Le Grange, Daniel; Crosby, Ross D.; Hoste, Renee Rienecke; Doyle, Angela Celio; Smyth, Angela; Herzog, David B.

    2010-01-01

    Objective: The purpose of this study was to empirically derive eating disorder phenotypes in a clinical sample of children and adolescents using latent profile analysis (LPA), and to compare these latent profile (LP) groups to the DSM-IV-TR eating disorder categories. Method: Eating disorder symptom data collected from 401 youth (aged 7 through 19…

  2. Brief Report: An Exploratory Study Comparing Diagnostic Outcomes for Autism Spectrum Disorders under DSM-IV-TR with the Proposed DSM-5 Revision

    Science.gov (United States)

    Gibbs, Vicki; Aldridge, Fiona; Chandler, Felicity; Witzlsperger, Ellen; Smith, Karen

    2012-01-01

    The proposed revision for Autism spectrum disorders (ASDs) in the Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition (DSM-5) represents a shift from the Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition, Text Revision (DSM-IV-TR). As the proposed DSM-5 criteria require a higher minimum number of symptoms to be…

  3. The Relationship between the "Childhood Autism Rating Scale: Second Edition" and Clinical Diagnosis Utilizing the DSM-IV-TR and the DSM-5

    Science.gov (United States)

    Dawkins, Tamara; Meyer, Allison T.; Van Bourgondien, Mary E.

    2016-01-01

    "The Childhood Autism Rating Scale, Second Edition" (CARS2; 2010) includes two rating scales; the CARS2-Standard Version (CARS2-ST) and the newly developed CARS2-High Functioning Version (CARS2-HF). To assess the diagnostic agreement between the CARS2 and DSM-IV-TR versus DSM-5 criteria for Autism Spectrum Disorder (ASD), clinicians at…

  4. Logística Reversa: Uma Análise Comparativa entre Três Processos Reversos de Resíduos Vítreos

    Directory of Open Access Journals (Sweden)

    Joaquim Carlos Lourenço

    2012-12-01

    Full Text Available O presente estudo tem por objetivo fazer uma análise comparativa entre três processos de logística reversa de resíduos vítreos. Para tanto, foi adotado como método, a pesquisa descritiva, e para coleta de dados a pesquisa bibliográfica. Na análise comparativa dos processos foram utilizados destaques que identificam os itens: Convergência entre os três processos; Divergência entre os três processos; e convergência parcial entre os processos. Assim, para cada item em análise, foi aplicado uma dessas três dimensões para comparar o processo reverso descrito nos estudos. O modelo de análise foi adaptado de Miranda et al. (2003. Os resultados encontrados apontam que os processos logísticos reversos descritos proporcionam vantagens econômicas e ambientais para as empresas. Por outro lado, a implantação dos processos reversos demanda investimentos altos, bem como o mapeamento e padronização dos processos de produção, aspectos estes que supostamente poderão contribuir a continuidade do empreendimento quando adotar esse tipo de prática empresarial.

  5. Reliability and validity of the DSM-IV-TR and proposed DSM-5 criteria for pedophilia: Implications for the ICD-11 and the next DSM.

    Science.gov (United States)

    Seto, Michael C; Fedoroff, J Paul; Bradford, John M; Knack, Natasha; Rodrigues, Nicole C; Curry, Susan; Booth, Brad; Gray, Jonathan; Cameron, Colin; Bourget, Dominique; Messina, Sarina; James, Elizabeth; Watson, Diane; Gulati, Sanjiv; Balmaceda, Rufino; Ahmed, Adekunle G

    We tested the inter-rater reliability and criterion-related validity of the DSM-IV-TR pedophilia diagnosis and proposed DSM-5 pedohebephilia diagnosis in a sample of 79 men who had committed child pornography offenses, contact sexual offenses against children, or who were referred because of concerns about whether they had a sexual interest in children. Participants were evaluated by two independent psychiatrists with an interview and questionnaire regarding demographic characteristics, sexual history, and self-reported sexual interests; they also completed phallometric and visual reaction time testing. Kappa was .59 for ever meeting DSM-IV-TR criteria for pedophilia and .52 for ever meeting the proposed DSM-5 criteria for pedohebephilia. Ever meeting DSM-IV-TR diagnosis was significantly related to self-reported index of sexual interest in children (highest AUC=.81, 95% CI=.70-.91, pDSM-5 "diagnosis" was similarly related to self-report (AUC=.84, 95% CI=.74-.94, pDSM-5 criteria, we believe these results suggest the revision of DSM-5 and development of ICD-11 could benefit from drawing on the current DSM-5 criteria, which are essentially the same as DSM-IV-TR except for a distinction between having a paraphilia (the interest) and a paraphilic disorder (the paraphilia plus clinically significant distress or impairment). Copyright © 2016. Published by Elsevier Ltd.

  6. Incidence of total hip or knee replacement due to osteoarthritis in relation to thyroid function: a prospective cohort study (The Nord-Trøndelag Health Study)

    OpenAIRE

    Hellevik, Alf Inge; Johnsen, Marianne Bakke; Langhammer, Arnulf; Fenstad, Anne Marie; Furnes, Ove; Storheim, Kjersti; Zwart, John-Anker; Flugsrud, Gunnar B; Nordsletten, Lars

    2017-01-01

    Background To study whether thyroid function was associated with risk of hip or knee replacement due to primary osteoarthritis. Methods In a prospective cohort study, data from the second and third survey of the Nord-Trøndelag Health Study were linked to the Norwegian Arthroplasty Register in order to identify total hip or knee replacement as a result of primary osteoarthritis. ...

  7. The role of subsite +2 of the Trichoderma reesei beta-mannanase TrMan5A in hydrolysis and transglycosylation

    DEFF Research Database (Denmark)

    Rosengren, Anna; Hägglund, Per; Anderson, Lars Steen

    2012-01-01

    The N-terminal catalytic module of beta-mannanase TrMan5A from the filamentous fungus Trichoderma reesei is classified into family 5 of glycoside hydrolases. It is further classified in clan A with a (beta/alpha)(8) barrel configuration and has two catalytic glutamates (E169 and E276). It has at ...

  8. Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex.

    Directory of Open Access Journals (Sweden)

    Siyuan Ding

    2016-10-01

    Full Text Available Rotaviruses (RVs are the leading cause of severe gastroenteritis in young children, accounting for half a million deaths annually worldwide. RV encodes non-structural protein 1 (NSP1, a well-characterized interferon (IFN antagonist, which facilitates virus replication by mediating the degradation of host antiviral factors including IRF3 and β-TrCP. Here, we utilized six human and animal RV NSP1s as baits and performed tandem-affinity purification coupled with high-resolution mass spectrometry to comprehensively characterize NSP1-host protein interaction network. Multiple Cullin-RING ubiquitin ligase (CRL complexes were identified. Importantly, inhibition of cullin-3 (Cul3 or RING-box protein 1 (Rbx1, by siRNA silencing or chemical perturbation, significantly impairs strain-specific NSP1-mediated β-TrCP degradation. Mechanistically, we demonstrate that NSP1 localizes to the Golgi with the host Cul3-Rbx1 CRL complex, which targets β-TrCP and NSP1 for co-destruction at the proteasome. Our study uncovers a novel mechanism that RV employs to promote β-TrCP turnover and provides molecular insights into virus-mediated innate immunity inhibition.

  9. La epidemiología como herramienta de estudio para la prevención de lesiones por accidente de tráfico (Parte 2)

    OpenAIRE

    Luzón Narro, Benito Javier; Seguí Gómez, María; López Valdés, Francisco; Arregui Dalmases, Carlos

    2006-01-01

    Continuació de l'article "La epidemiología como herramienta de estudio para la prevención de lesiones por accidente de tráfico (Parte 1)" http://hdl.handle.net/2117/15731 Clasificación de la gravedad de las lesiones; Investigación de los accidentes "en profundidad". Peer Reviewed

  10. Combined lymphangioma and hemangioma of the spleen in a patient with Klippel–Trénaunay syndrome

    Directory of Open Access Journals (Sweden)

    Spasić Marko

    2012-01-01

    Full Text Available Introduction. Klippel–Trénaunay syndrome (KTS is a very rare congenital anomaly of blood vessels, characterized by the following clinical triad: varicose superficial veins, port-wine stain and usually bony and soft tissue hypertophy of extremities, most often located in the lower extremities. It is often accompanied by visceral manifestations, and rarely combined with splenomegaly. Case Outline. A 30-year-old female patient came to the Surgery Clinic because of occasional left hypochondrial pain. After she was diagnosed with KTS combined with splenomegaly, splenectomy was performed. Macroscopic and microscopic spleen examination indicated the presence of tumor of vascular origin, presenting a combination of lymphangioma and hemangioma. Conclusion. Diagnosed KTS demands a thorough clinical examination of the patient because of the potential presence of visceral manifestations. When splenomegaly is present, even though being often benign, splenectomy is usually performed to alleviate accompanying symptoms which occur as a result of organ enlargement and compression, to prevent rupture and consequential bleeding when the vascular spleen tumor is large, and finally to avoid a possibility of malignant transformation.

  11. Linfangioleiomiomatose - A propósito de três casos clínicos Lymphangioleiomyomatosis - report of three cases

    Directory of Open Access Journals (Sweden)

    Carla Valente

    2010-01-01

    Full Text Available A linfangioleiomiomatose (LAM é uma doença rara, de etiologia desconhecida, caracterizada pela proliferação anormal de células musculares lisas nas regiões perilinfática, perivascular e peribrônquica. A LAM pode ocorrer esporadicamente ou associada ao complexo esclerose tuberosa (CET e hamartose hereditária multiorgânica. Em ambas as situações a LAM afecta principalmente mulheres jovens em idade fértil, sendo que aproximadamente 1/3 das mulheres com CET têm LAM. A propósito desta patologia, os autores elaboram uma revisão da literatura e descrevem os casos clínicos de três doentes do sexo feminino com o diagnóstico de LAM com base nos achados clínicos e imagiológicos.Pulmonary lymphangioleiomyomatosis (LAM is a rare disease of unknown aetiology. It is characterized by proliferation of abnormal smooth-muscle cells throughout the peribronchial, perivascular and perilymphatic regions of the lung. LAM may occur sporadically, in association with tuberous sclerosis complex (TSC or inheritable multiorgan hamartomatosis. In either situation, LAM occurs almost exclusively in women of reproductive age, and approximately one third of the patients with TSC have LAM. The authors review the cases of three female patients diagnosed with LAM based on clinical and radiological findings. A brief review of the disease is then presented.

  12. Três casamentos e algumas reflexões: Notas sobre conjugalidade envolvendo travestis que se prostituem

    Directory of Open Access Journals (Sweden)

    Larissa Pelúcio

    2006-05-01

    Full Text Available http://dx.doi.org/10.1590/S0104-026X2006000200012 A partir de uma abordagem antropológica que dialoga com a teoria queer, analisamse três experiências de conjugalidade envolvendo travestis que se prostituem, discutindo-se os limites dessas relações, impostos pela visão de mundo que orienta as travestis, pessoas pertencentes em sua maioria às camadas populares e, de acordo com a hipótese que se coloca, tributárias de uma visão de mundo holista. Assim, observa-se que as relações conjugais vêm fortemente orientadas por perspectivas essencialista quanto ao sexo e ao gênero, atribuindo papéis rigidamente estabelecidos para cada parceiro. Ao naturalizar o sexo que exige um gênero supostamente coerente a essa anatomia que elas simplesmente não aceitam como destino, mantêm-se atadas à matriz heteronormatizadora. Informadas por uma gramática de conjugalidade heterossexual, elas encontram dificuldades em elaborar um outro léxico para as relações conjugais.

  13. The 3-D strain patterns in Turkey using geodetic velocity fields from the RTK-CORS (TR) network

    Science.gov (United States)

    Kutoglu, Hakan Senol; Toker, Mustafa; Mekik, Cetin

    2016-03-01

    This study presents our use of GPS data to obtain and quantify the full continuous strain tensor using a 3-D velocity field in Turkey. In this study, GPS velocities improve the estimation of short-term strain tensor fields for determining the seismic hazard of Turkey. The tensorial analysis presents different aspects of deformation, such as the normal and shear strains, including their directions, the compressional and extensional strains. This analysis is appropriate for the characterizing the state of the current seismic deformation. GPS velocity data from continuous measurements (2009-2012) to estimate deformations were processed using the GAMIT/GLOBK software. Using high-rate GPS data from permanent 146 GNSS stations (RTK-CORS-TR network), the strain distribution was determined and interpolated using a biharmonic spline technique. We show the strain field patterns within axial and plane form at several critical locations, and discuss these results within the context of the seismic and tectonic deformation of Turkey. We conclude that the knowledge of the crustal strain patterns provides important information on the location of the main faults and strain accumulation for the hazard assessment. The results show an agreement between the seismic and tectonic strains confirming that there are active crustal deformations in Turkey.

  14. Análise do Comportamento de Compra de Três Segmentos de Consumidores nos Supermercados

    Directory of Open Access Journals (Sweden)

    Sheila Farias Alves Garcia

    2010-06-01

    Full Text Available O ambiente atual caracterizado pelas mudanças estruturais do mercado, pela entrada de concorrentes internacionais e pela concentração do setor, aponta o surgimento de um novo modelo de gestão nas organizações varejistas, pautado pela eficiência e foco no consumidor. Os varejistas devem se adequar ao modelo de criação de valor para os clientes, o que implica conhecer profundamente o consumidor, acompanhando as suas necessidades, mudanças e tendências, com o objetivo de se adaptar às novas exigências do mercado. Nesse contexto, este artigo parte da necessidade, cada vez maior, de compreender e considerar o consumidor, apresentando e analisando o comportamento de três segmentos de consumidores (idosos, sozinhos e mulheres chefes de família, que demonstram, segundo dados do IBGE (2005, um aumento significativo na população (61% nos últimos anos. O objetivo do presente ensaio é investigar o comportamento desses segmentos de consumidores que frequentam supermercados e verificar possíveis estratégias e oportunidades na criação e fortalecimento de um relacionamento de valor com eles, a partir de necessidades distintas. DOI: 10.5585/remark.v9i1.2150

  15. X-band T/R switch with body-floating multi-gate PDSOI NMOS transistors

    Science.gov (United States)

    Park, Mingyo; Min, Byung-Wook

    2018-03-01

    This paper presents an X-band transmit/receive switch using multi-gate NMOS transistors in a silicon-on-insulator CMOS process. For low loss and high power handling capability, floating body multi-gate NMOS transistors are adopted instead of conventional stacked NMOS transistors, resulting in 53% reduction of transistor area. Comparing to the stacked NMOS transistors, the multi gate transistor shares the source and drain region between stacked transistors, resulting in reduced chip area and parasitics. The impedance between bodies of gates in multi-gate NMOS transistors is assumed to be very large during design and confirmed after measurement. The measured input 1 dB compression point is 34 dBm. The measured insertion losses of TX and RX modes are respectively 1.7 dB and 2.0 dB at 11 GHz, and the measured isolations of TX and RX modes are >27 dB and >20 dB in X-band, respectively. The chip size is 0.086 mm2 without pads, which is 25% smaller than the T/R switch with stacked transistors.

  16. Tráfico y tenencia ilegal de fauna silvestre en el departamento de Boyacá

    Directory of Open Access Journals (Sweden)

    Alejandro Cabrejo Bello

    2010-10-01

    Full Text Available Con el fin de establecer cuáles son los principales grupos taxonómicos, suparticipación y las ciudades con mayores índices de tráfico y tenencia ilegal de vida silvestre en el departamento de Boyacá, jurisdicción de la Corporación Autónoma Regional de Boyacá- Corpoboyacá, se tomaron reportes de la base de datos de dicha entidad entre los años 2004 y 2008. Se hallaron registros de 398 individuos decomisados por parte de la autoridad ambiental y otros por entregas voluntarias. El grupo con mayor incidencia fue el de las aves con 58%,seguido por los reptiles con 26% y en tercer lugar los mamíferos con el 16% de los registros. Se observó que las tres principales ciudades del departamento (Tunja, Duitama y Sogamoso reportan las frecuencias más elevadas de incautaciones. Puerto Boyacá, también registra un número elevado de decomisos. Dentro de los tres grupos mencionados, las especies más afectadas correspondena los órdenes Psitaciformes, Primates y Testudínata, por lo cual merecen principal atención. Se recomienda además, implementar planes de conservación y emprender actividades de educación ambiental encaminadas a la utilización sostenible de la fauna en general.

  17. Determination and assessment of the concentration limits to be used in SR-Can. Supplement to TR-06-32

    Energy Technology Data Exchange (ETDEWEB)

    Grive, Mireia; Domenech, Cristina; Montoya, Vanessa; Garcia, David; Duro, Lara

    2010-09-15

    This document complements and updates the report TR-06-32, Determination and assessment of the concentration limits to be used in SR-Can, in which the solubility limits of different radionuclides in the near field system and under the different scenarios selected by SKB were assessed. Since 2006, several important changes in different fields affecting solubility assessment calculations have been reported. These changes basically concern some of the thermodynamic data used in the calculations and the groundwater compositions for scenarios of interest defined by SKB. In this document we update the thermodynamic data corresponding to Ni, Zr, Th and U and we describe the thermodynamic database selected for Pb. This document also reports the update of the assessment of the concentration limits to be used in SR-Can, which has been done considering the recent thermodynamic database updates and the new groundwater compositions of interest supplied by SKB. Finally, we also present the Simple Functions spreadsheet tool, born from the need of having a confident and easy-to-handle tool to calculate solubility limits of some radionuclides under determined conditions in an agile and relatively fast manner

  18. Intermittent simulated moving bed chromatography: 3. Separation of Tröger's base enantiomers under nonlinear conditions.

    Science.gov (United States)

    Katsuo, Shigeharu; Langel, Christian; Sandré, Anne-Laure; Mazzotti, Marco

    2011-12-30

    One of the modified simulated moving bed (SMB) processes, the intermittent SMB (I-SMB) process, has been recently analyzed theoretically [1] and its superior performance compared to the conventional SMB process has been demonstrated at a rather low total feed concentration through experiments and simulations [2]. This work shows that the I-SMB process outperforms the conventional SMB process also at high feed concentration where the species are clearly subject to a nonlinear adsorption isotherm. In the case of the separation of the Tröger's base's enantiomers in ethanol on ChiralPak AD, the two processes operated in a six-column 1-2-2-1 configuration (one column in sections 1 and 4 and two columns in sections 2 and 3) and in a four-column 1-1-1-1 configuration (one column in each section) are compared at high feed concentration through both experiments and simulations. Even under nonlinear conditions the four column I-SMB process can successfully separate the two enantiomers achieving purity levels as high as the two six column processes and exhibiting better productivity. Copyright © 2011 Elsevier B.V. All rights reserved.

  19. The Eurasian eagle-owl (Bubo bubo diet in the Trøndelag region (Central Norway

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    Obuch Ján

    2016-12-01

    Full Text Available Between 2008 and 2015 we collected pellets of the Eurasian eagle-owl (Bubo bubo in the Trøndelag region of central Norway and identified the food remains in these samples. We collected material at 45 sites with samples from a total of 76 nests. Some of the samples were from older and already abandoned nests, but at several sites we also found and collected fresh B. bubo pellets. In total 40,766 items of prey were identified from the osteological material. The most dominant food components were mammals (Mammalia, 25 species, 63.5%. The species representation of birds was very diverse (Aves, more than 150 species, 19.4%. Of amphibians (Amphibia, 1 6.8%, the well-represented species were Rana temporaria. Fish (Pisces, 0.3% were represented rarely, while invertebrates were represented only sporadically (Invertebrata, 0.05%. A special composition was found in the diet spectra of the mammals and birds in the mountainous areas at altitudes between 220-780 m above sea level. The highest proportion of frogs was found in areas in the proximity of the mainland shore. On the northern islands located near the coast a significant proportion of the B. bubo diet consisted of rodents (Rodentia. On the more isolated southern islands of Frøya, Hitra and Storfosna the main prey was sea birds, and of the mammals there were also hedgehogs and rats.

  20. Fatores associados ao óbito de motociclistas nas ocorrências de trânsito

    Directory of Open Access Journals (Sweden)

    Nelson Luiz Batista de Oliveira

    Full Text Available Para identificar fatores associados ao óbito em motociclistas envolvidos em ocorrências de trânsito, em Maringá-PR, foi realizado estudo retrospectivo incluindo os motociclistas envolvidos em acidentes no ano de 2004. As fontes de dados foram os registros da Polícia Militar, do SIATE e do Instituto Médico Legal. Foram realizadas análises bivariadas e regressão logística binária. Identificaram-se 2.362 motociclistas nos Boletins de Ocorrência e, destes, 1.743 tinham registros nos Relatórios de Atendimento do Socorrista. As vítimas fatais diferiram das demais quanto à faixa etária, ao local de residência, ao tempo de habilitação e as suas condições fisiológicas na cena da ocorrência. No modelo final permaneceram as seguintes variáveis: Escala de Coma de Glasgow (ECGl, Revised Trauma Score (RTS, pulso e saturação de O2 no sangue. As condições fisiológicas das vítimas na cena do acidente se destacaram no modelo final e a ECGl superou o RTS na associação com óbito.