Research Article Special Issue

African Journals Online (AJOL)

2017-02-15

Feb 15, 2017 ... Research Article. Special Issue ... In myriad studies implemented, the quality of life has been defined in different ways among which the .... service and trading users in living area. ... market, bakery, barber shop, restaurant, etc.

Special issue on asteroids - Introduction

Science.gov (United States)

Novaković, Bojan; Hsieh, Henry H.; Gronchi, Giovanni F.

2018-04-01

The articles in this special issue are devoted to asteroids, small solar system bodies that primarily populate a region between the orbits of Mars and Jupiter, known as the asteroid belt, but can also be found throughout the Solar System. Asteroids are considered to be a key to understanding the formation and evolution of our planetary system. Their properties allow us to test current theoretical models and develop new theoretical concepts pertaining to evolutionary processes in the Solar System. There have been major advances in asteroid science in the last decade, and that trend continues. Eighteen papers accepted for this special issue cover a wide range of asteroid-related subjects, pushing the boundaries of our understanding of these intriguing objects even further. Here we provide the reader with a brief overview of these thrilling papers, with an invitation for interested scientists to read each work in detail for a better understanding of these recent cutting edge results. As many topics in asteroid science remain open challenges, we hope that this special issue will be an important reference point for future research on this compelling topic.

Special issue: Plasma Conversion

NARCIS (Netherlands)

Nozaki, T.; Bogaerts, A.; Tu, X.; van de Sanden, M. C. M.

2017-01-01

With growing concern of energy and environmental issues, the combination of plasma and heterogeneous catalysts receives special attention in greenhouse gas conversion, nitrogen fixation and hydrocarbon chemistry. Plasma gas conversion driven by renewable electricity is particularly important for the

Special issue on quantum physics with non-Hermitian operators Special issue on quantum physics with non-Hermitian operators

Science.gov (United States)

Bender, Carl M.; Fring, Andreas; Guenther, Uwe; Jones, Hugh F.

2012-01-01

This is a call for contributions to a special issue of Journal of Physics A: Mathematical and Theoretical dedicated to quantum physics with non-Hermitian operators. The main motivation behind this special issue is to gather together recent results, developments and open problems in this rapidly evolving field of research in a single comprehensive volume. We expect that such a special issue will become a valuable reference for the broad scientific community working in mathematical and theoretical physics. The issue will be open to all contributions containing new results on non-Hermitian theories which are explicitly PT-symmetric and/or pseudo-Hermitian or quasi-Hermitian. The main novelties in the past years in this area have been many experimental observations, realizations, and applications of PT symmetric Hamiltonians in optics and microwave cavities. We especially invite contributions on the theoretical interpretations of these recent PT-symmetric experiments and on theoretical proposals for new experiments. Editorial policy The Guest Editors for this issue are Carl Bender, Andreas Fring, Uwe Guenther and Hugh Jones. The areas and topics for this issue include, but are not limited to: spectral problems novel properties of complex optical potentials PT-symmetry related threshold lasers and spectral singularities construction of metric operators scattering theory supersymmetric theories Lie algebraic and Krein-space methods random matrix models classical and semi-classical models exceptional points in model systems operator theoretic approaches microwave cavities aspects of integrability and exact solvability field theories with indefinite metric All contributions will be refereed and processed according to the usual procedure of the journal. Papers should report original and significant research that has not already been published. Guidelines for preparation of contributions The deadline for contributed papers will be 31 March 2012. This deadline will allow the

Special Issue: War, violence and masculinities

DEFF Research Database (Denmark)

2015-01-01

This special double issue of NORMA explore the mutual influences between violence, war and masculinities, the forms these have taken in different social and cultural contexts and the implications for masculinity research. The issues cover a range of historical and current topics, cases and analyt......This special double issue of NORMA explore the mutual influences between violence, war and masculinities, the forms these have taken in different social and cultural contexts and the implications for masculinity research. The issues cover a range of historical and current topics, cases...... and analytical approaches. The contributions fall into the following four themes: violent masculine rituals and how contemporary societies cope with extreme violence against women; popular written and visual fiction about war and masculine rationalities; gender relations in social movements of rebellions...

Special Issue: “Molecules against Alzheimer”

Directory of Open Access Journals (Sweden)

Michael Decker

2016-12-01

Full Text Available This Special Issue, entitled “Molecules against Alzheimer”, gathers a number of original articles, short communications, and review articles on recent research efforts toward the development of novel drug candidates, diagnostic agents and therapeutic approaches for Alzheimer’s disease (AD, the most prevalent neurodegenerative disorder and a leading cause of death worldwide. This Special Issue contains many interesting examples describing the design, synthesis, and pharmacological profiling of novel compounds that hit one or several key biological targets, such as cholinesterases, β-amyloid formation or aggregation, monoamine oxidase B, oxidative stress, biometal dyshomeostasis, mitochondrial dysfunction, serotonin and/or melatonin systems, the Wnt/β-catenin pathway, sigma receptors, nicotinamide phosphoribosyltransferase, or nuclear erythroid 2-related factor. The development of novel AD diagnostic agents based on tau protein imaging and the use of lithium or intranasal insulin for the prevention or the symptomatic treatment of AD is also covered in some articles of the Special Issue.

2007 TOXICOLOGY AND RISK ASSESSMENT ...

Science.gov (United States)

EPA has announced The 2007 Toxicology and Risk Assessment Conference Cincinnati Marriott North, West Chester (Cincinnati), OHApril 23- 26, 2007 - Click to register!The Annual Toxicology and Risk Assessment Conference is a unique meeting where several Government Agencies come together to discuss toxicology and risk assessment issues that are not only of concern to the government, but also to a broader audience including academia and industry. The theme of this year's conference is Emerging Issues and Challenges in Risk Assessment and the preliminary agenda includes: Plenary Sessions and prominent speakers (tentative) include: Issues of Emerging Chemical ContaminantsUncertainty and Variability in Risk Assessment Use of Mechanistic data in IARC evaluationsParallel Sessions:Uncertainty and Variability in Dose-Response Assessment Recent Advances in Toxicity and Risk Assessment of RDX The Use of Epidemiologic Data for Risk Assessment Applications Cumulative Health Risk Assessment:

Special issue on coherent states: mathematical and physical aspects Special issue on coherent states: mathematical and physical aspects

Science.gov (United States)

Twareque Ali, Syed; Antoine, Jean-Pierre; Bagarello, Fabio; Gazeau, Jean-Pierre

2011-07-01

This is a call for contributions to a special issue of Journal of Physics A: Mathematical and Theoretical dedicated to coherent states. The motivation behind this special issue is to gather in a single comprehensive volume the main aspects (past and present), latest developments, different viewpoints and directions being followed in this multidisciplinary field. Given the impressive development of the field in the past two decades, the topicality of such a volume can hardly be overemphasized. We strongly believe that such a special issue could become a particularly valuable reference for the broad scientific community working in mathematical and theoretical physics, as well as in signal processing and mathematics. Editorial policy The Guest Editors for this issue will be Syed Twareque Ali, Jean-Pierre Antoine, Fabio Bagarello and Jean-Pierre Gazeau. Potential topics include, but are not limited to, developments in the theory and applications of coherent states in: quantum optics, optomechanics, Bose-Einstein condensates quantum information, quantum measurement signal processing quantum gravity pseudo-Hermitian quantum mechanics supersymmetric quantum mechanics non-commutative quantum mechanics quantization theory harmonic and functional analysis operator theory Berezin-Toeplitz operators, PT-symmetric operators holomorphic representation theory, reproducing kernel spaces generalization of coherent states All contributions will be refereed and processed according to the usual procedure of the journal. Papers should report original and significant research that has not already been published. Guidelines for preparation of contributions The deadline for contributed papers will be 31 October 2011. This deadline will allow the special issue to appear before the end of May 2012 There is a nominal page limit of 15 printed pages per contribution (invited review papers can be longer). For papers exceeding this limit, the Guest Editors reserve the right to request a

Research Article Special Issue

African Journals Online (AJOL)

pc

2018-02-01

Feb 1, 2018 ... the Russian philosophical and sociological thought. The thoughts of the Russian scientist ... Research Article. Special Issue. Journal of Fundamental and Applied Sciences is licensed under a Creative Commons Attribution-NonCommercial 4.0. International License. Libraries Resource Directory. We are ...

Research Article Special Issue

African Journals Online (AJOL)

pc

2017-10-05

Oct 5, 2017 ... Journal of Fundamental and Applied Sciences. ISSN 1112-9867. Available online at http://www.jfas.info. Research Article. Special Issue .... of use. Three critical success factors of e-learning (instructor characteristics, student characteristics .... Total of 95 questionnaires were used for further data analysis.

Resource Guide to Careers in Toxicology, 3rd Edition.

Science.gov (United States)

Society of Toxicology, Reston, VA.

This resource guide was prepared by the Tox 90's Educational Issues Task Force of the Society of Toxicology. The introduction provides information on the Society of Toxicology and financial support for graduate students in toxicology. Other sections include career opportunities in toxicology, academic and postdoctoral programs in toxicology, and…

Ninth Triennial Toxicology Salary Survey.

Science.gov (United States)

Gad, Shayne Cox; Sullivan, Dexter Wayne

2016-01-01

This survey serves as the ninth in a series of toxicology salary surveys conducted at 3-year intervals and beginning in 1988. An electronic survey instrument was distributed to 5919 individuals including members of the Society of Toxicology, American College of Toxicology, and 23 additional professional organizations. Question items inquired about gender, age, degree, years of experience, certifications held, areas of specialization, society membership, employment and income. Overall, 1293 responses were received (response rate 21.8%). The results of the 2014 survey provide insight into the job market and career path for current and future toxicologists. © The Author(s) 2016.

Special Issue: Candida and Candidiasis

Directory of Open Access Journals (Sweden)

Jeniel E. Nett

2018-06-01

Full Text Available This special issue highlights emerging topics related to Candida, the most prevalent fungal pathogen in the hospital setting. The advantages and limitations of new, non-culture based diagnostic techniques are discussed. The issue reviews mammalian and non-mammalian infection models. The manuscripts present updates on several molecular mechanisms of pathogenicity, including filamentation, biofilm formation, and phospholipid production.

Research Article Special Issue

African Journals Online (AJOL)

2016-05-15

May 15, 2016 ... Research Article. Special Issue. Journal of Fundamental and Applied Sciences is licensed under a Creative Commons Attribution-NonCommercial 4.0. International License. ... innovation is defined as: accepting ideas or behaviors in the organization that are novel and unfamiliar. Innovation can be in form ...

Research Article Special Issue

African Journals Online (AJOL)

2017-10-05

Oct 5, 2017 ... We are listed under Research Associations. D THAT USES A ... Clinical Engineering, Toin University of Yokohama, Yokohama, Aoba ... Special Issue ..... advisable to run the prognosis results at least one hundred times with the Euclidean and ... They are some of the topics left for future research. 5.

Toxicology in Asia--Past, present, and future.

Science.gov (United States)

Satoh, T

2015-12-01

The Asian Society of Toxicology (ASIATOX), which consists of the seven national toxicology member societies of Japan, Korea, China, Taiwan, Thailand, Singapore, and Iran, now boasts of more than 3,000 members from a variety of industries, academia, and regulatory organizations. ASIATOX congresses are spaced three years apart and rotated among the member societies. In 1995, ASIATOX joined the International Union of Toxicology (IUTOX) as a regional society, and now serves as the scientific voice of toxicology in Asia under the IUTOX umbrella. Since its inauguration, the society has worked diligently to handle matters deemed essential to promoting the vision set fourth by its founders. Future perspectives of ASIATOX include the establishment of education and training programs, and the certification and accreditation of toxicologists. As the leading voice of toxicology in Asia, the society seeks to extend knowledge of toxicological issues to developing nations in Asia based on the following missions and goals: (1) to provide leadership as a worldwide scientific organization that objectively addresses global issues involving the toxicological sciences, (2) to broaden the geographical base of toxicology as a discipline and profession to all countries of the world, and (3) to pursue capacity building in toxicology, particularly in developing countries, while utilizing its global perspective and network to contribute to the enhancement of toxicology education and the career development of young toxicologists. © The Author(s) 2015.

Collection of biological samples in forensic toxicology.

Science.gov (United States)

Dinis-Oliveira, R J; Carvalho, F; Duarte, J A; Remião, F; Marques, A; Santos, A; Magalhães, T

2010-09-01

Forensic toxicology is the study and practice of the application of toxicology to the purposes of the law. The relevance of any finding is determined, in the first instance, by the nature and integrity of the specimen(s) submitted for analysis. This means that there are several specific challenges to select and collect specimens for ante-mortem and post-mortem toxicology investigation. Post-mortem specimens may be numerous and can endow some special difficulties compared to clinical specimens, namely those resulting from autolytic and putrefactive changes. Storage stability is also an important issue to be considered during the pre-analytic phase, since its consideration should facilitate the assessment of sample quality and the analytical result obtained from that sample. The knowledge on degradation mechanisms and methods to increase storage stability may enable the forensic toxicologist to circumvent possible difficulties. Therefore, advantages and limitations of specimen preservation procedures are thoroughfully discussed in this review. Presently, harmonized protocols for sampling in suspected intoxications would have obvious utility. In the present article an overview is given on sampling procedures for routinely collected specimens as well as on alternative specimens that may provide additional information on the route and timing of exposure to a specific xenobiotic. Last, but not least, a discussion on possible bias that can influence the interpretation of toxicological results is provided. This comprehensive review article is intented as a significant help for forensic toxicologists to accomplish their frequently overwhelming mission.

Research Article Special Issue

African Journals Online (AJOL)

2018-01-15

Jan 15, 2018 ... Journal of Fundamental and Applied Scienc. ISSN 1112-9867 ... (0.9623, 0.3857) and (0.9975, ity, temperature, CO, UVB and. 10 concentration. In by using ANN or Fit model. Research Article. Special Issue .... The EM algorithm is a simple computational implementation to find the posterior mode. Fig.

Overview of Special Issue

NARCIS (Netherlands)

Hiemstra, Djoerd; Harman, Donna; Allan, James; Kelly, Diane; Belkin, Nicholas J.; Bennet, Paul; Callan, Jamie; Clarke, Charles; Diaz, Fernando; Dumais, Susan; Ferro, Nicola; Harman, Donna; Ruthven, Ian; Sakai, Tetsuya; Smucker, Mark D.; Zobel, Justin

2017-01-01

This special issue of SIGIR Forum marks the 40th anniversary of the ACM SIGIR Conference by showcasing papers selected for the ACM SIGIR Test of Time Award from the years 1978-2001. These papers document the history and evolution of IR research and practice, and illustrate the intellectual impact

Research Article Special Issue

African Journals Online (AJOL)

2016-06-05

Jun 5, 2016 ... because Amir al- Mu'minin's(peace be upon him) name is related to human perfection and. Journal of Fundamental and Applied Sciences. ISSN 1112-9867. Available online at http://www.jfas.info. Research Article. Special Issue. Journal of Fundamental and Applied Sciences is licensed under a Creative ...

Toxicology research projects directory, 1978. Monthly repts

International Nuclear Information System (INIS)

1978-01-01

The Toxicology Research Projects Directory is a monthly publication of ongoing research projects in toxicology and related fields selected from the files of the Smithsonian Science Information Exchange (SSIE). Each issue lists toxicology-related research projects reported to SSIE during the one-month period preceding that issue. Each of the summaries is categorized by scientific discipline and assigned a unique identification number for cross-referencing from the Directory Indexes--Subject, Investigator, Performing Organization, Supporting Agency, and Master Grant Number. The thirteenth issue consists of Cumulative Indexes for the entire volume with referencing to projects in all of the previous twelve issues. The emphasis of the Directory is on the manifestations of the exposure of man and animals to toxic substances. Projects are classified by toxic agents, research orientation, and areas of environmental concern

Call for another special issue / book

Science.gov (United States)

Bostenaru Dan, M.

2009-04-01

We would like to continue the series of special issue or maybe edit a book on this topic. To complete the formerly edited special issues we would like to link natural hazards research to cultural heritage research. We see a way of doing this connected to "integrated conservation", which sees the involvment of urban planning in conservation, as well as the (urban) sociology, the integration of the user, the participatism. We further call for investigation of GIS applications for the investigation of natural hazards' impact in this field. We are open for further ideas and wait for you at the Splinter meeting.

Special Issue: Selected papers from ECS'97

DEFF Research Database (Denmark)

1999-01-01

This Special Issue of Analog Integrated Circuits and Signal Processing presents extended versions of selected papers from the First Electronic Circuits and Systems Conference (ECS'97) which was held on September 4-5, 1997, in Bratislava, Slovakia.......This Special Issue of Analog Integrated Circuits and Signal Processing presents extended versions of selected papers from the First Electronic Circuits and Systems Conference (ECS'97) which was held on September 4-5, 1997, in Bratislava, Slovakia....

A primer on systematic reviews in toxicology.

Science.gov (United States)

Hoffmann, Sebastian; de Vries, Rob B M; Stephens, Martin L; Beck, Nancy B; Dirven, Hubert A A M; Fowle, John R; Goodman, Julie E; Hartung, Thomas; Kimber, Ian; Lalu, Manoj M; Thayer, Kristina; Whaley, Paul; Wikoff, Daniele; Tsaioun, Katya

2017-07-01

Systematic reviews, pioneered in the clinical field, provide a transparent, methodologically rigorous and reproducible means of summarizing the available evidence on a precisely framed research question. Having matured to a well-established approach in many research fields, systematic reviews are receiving increasing attention as a potential tool for answering toxicological questions. In the larger framework of evidence-based toxicology, the advantages and obstacles of, as well as the approaches for, adapting and adopting systematic reviews to toxicology are still being explored. To provide the toxicology community with a starting point for conducting or understanding systematic reviews, we herein summarized available guidance documents from various fields of application. We have elaborated on the systematic review process by breaking it down into ten steps, starting with planning the project, framing the question, and writing and publishing the protocol, and concluding with interpretation and reporting. In addition, we have identified the specific methodological challenges of toxicological questions and have summarized how these can be addressed. Ultimately, this primer is intended to stimulate scientific discussions of the identified issues to fuel the development of toxicology-specific methodology and to encourage the application of systematic review methodology to toxicological issues.

Research Article Special Issue

African Journals Online (AJOL)

pc

2017-10-17

Oct 17, 2017 ... Perak, Malaysia was observed under ral waste in powder and xtract generated optimum produce highest length of fectively improved shoot ed faster effect on C. ed positive result for the shed light on how the Z. C. nutans. This study ld application. pagation; Zea mays stem. Research Article. Special Issue ...

Guest Editorial Special Issue on Human Computing

NARCIS (Netherlands)

Pantic, Maja; Santos, E.; Pentland, A.; Nijholt, Antinus

2009-01-01

The seven articles in this special issue focus on human computing. Most focus on two challenging issues in human computing, namely, machine analysis of human behavior in group interactions and context-sensitive modeling.

Cybernetics and Education (Special Issue)

Science.gov (United States)

Kopstein, Felix F., Ed.

1977-01-01

This is a special issue examining the potential of cybernetics in educational technology. Articles discuss: cybernetic methods, algorithms, feedback learning theory, a structural approach to behavioral objectives and criterion-referenced testing, task specifications and diagnosis, teacher-child interaction, educational development, teaching…

Special Issue: Engineering Digital Transformation

Directory of Open Access Journals (Sweden)

Julio J. Garcia-Sabater

2018-04-01

We gratefully acknowledge the authors and particularly the reviewers, whose valuable comments have improved the quality of the selected papers, which were extended (and again reviewed by pairs after the conference in order to be published in this Special Issue.

Special issue on cluster algebras in mathematical physics

Science.gov (United States)

Di Francesco, Philippe; Gekhtman, Michael; Kuniba, Atsuo; Yamazaki, Masahito

2014-02-01

This is a call for contributions to a special issue of Journal of Physics A: Mathematical and Theoretical dedicated to cluster algebras in mathematical physics. Over the ten years since their introduction by Fomin and Zelevinsky, the theory of cluster algebras has witnessed a spectacular growth, first and foremost due to the many links that have been discovered with a wide range of subjects in mathematics and, increasingly, theoretical and mathematical physics. The main motivation of this special issue is to gather together reviews, recent developments and open problems, mainly from a mathematical physics viewpoint, into a single comprehensive issue. We expect that such a special issue will become a valuable reference for the broad scientific community working in mathematical and theoretical physics. The issue will consist of invited review articles and contributed papers containing new results on the interplays of cluster algebras with mathematical physics. Editorial policy The Guest Editors for this issue are Philippe Di Francesco, Michael Gekhtman, Atsuo Kuniba and Masahito Yamazaki. The areas and topics for this issue include, but are not limited to: discrete integrable systems arising from cluster mutations cluster structure on Poisson varieties cluster algebras and soliton interactions cluster positivity conjecture Y-systems in the thermodynamic Bethe ansatz and Zamolodchikov's periodicity conjecture T-system of transfer matrices of integrable lattice models dilogarithm identities in conformal field theory wall crossing in 4d N = 2 supersymmetric gauge theories 4d N = 1 quiver gauge theories described by networks scattering amplitudes of 4d N = 4 theories 3d N = 2 gauge theories described by flat connections on 3-manifolds integrability of dimer/Ising models on graphs. All contributions will be refereed and processed according to the usual procedure of the journal. Guidelines for preparation of contributions The deadline for contributed papers is 31 March

Virtual Special Issue on Migration

NARCIS (Netherlands)

Jordan, Declan; Elhorst, Paul

2016-01-01

This editorial introduces a virtual special issue of Spatial Economic Analysis compiled to mark the keynote lecture at the 46th Annual Conference of the Regional Science Association InternationalBritish and Irish Section in Cornwall by Professor Jacques Poot of the National Institute of Demographic

Special issue of photosynthetic research

NARCIS (Netherlands)

Okamura, M.; Wraight, C.A.; van Grondelle, R.

2014-01-01

This Special Issue of Photosynthesis Research honors Louis M. N. Duysens, Roderick K. Clayton, and George Feher, three pioneering researchers whose work on bacterial photosynthesis laid much of the groundwork for our understanding of the role of the reaction center in photosynthetic light energy

Editorial: Special Issue on Financial Planning

Directory of Open Access Journals (Sweden)

Mark Brimble

2012-11-01

Full Text Available AbstractThe special edition presents current research in the area of financial planning. With the continual upheaval inglobal financial markets (including Australia, the general trend towards self-funded retirement and lessreliance on the state, financial crises and the continual regulatory changes in the financial markets, this issue istimely and topical. This is the third special edition on financial planning, providing an excellent outlet forquality research in financial planning.

Regional and Special Issues in Social Policy & Administration

DEFF Research Database (Denmark)

Finer, Catherine Jones; Greve, Bent

2016-01-01

This article explores the emergence and elaboration of regional and special issues of Social Policy & Administration (SP&A) from the contrasting perspectives of the two editors principally involved in their production as a distinctive feature of the journal. Catherine Jones Finer, who retired from......-to-date range of documents to trace trends and developments over time, not merely in the content of the regional and special issues themselves, but in the increasingly international and supra-national social policy environment to which they relate....... editorial involvement in2007, writes from memory of her own experience (which featured the introduction of regional then special issues as an ongoing series) drawing on the run of printed copies of SP&A still in her possession. Bent Greve then draws on his own access to a much wider and more up...

Who, How, and Where: Special Education's Issues in Perpetuity.

Science.gov (United States)

Bateman, Barbara D.

1994-01-01

Issues that are central to special education and appear destined to remain so are discussed, including professional divisions among special educators and between special and regular educators, the population to be served, individualization, and placement. (JDD)

Introduction: Special issue on Global Lesbian Cinema.

Science.gov (United States)

Farr, Daniel

2012-01-01

This article offers a brief introduction to this special issue on Global Lesbian Cinema. This issue particularly highlights the importance of recognizing lesbian discourse as a separate, related piece of the discourse of queer transnational and global cinema. Subsequently, brief summaries of the eight articles of this collection are provided.

Special issue on the spectroscopy of transient plasmas

Science.gov (United States)

Bailey, James; Hoarty, David; Mancini, Roberto; Yoneda, Hitoki

2015-01-01

Experimental and theoretical papers are invited for a special issue of Journal of Physics B: Atomic, Molecular and Optical Physics on Spectroscopy of Transient Plasmas, covering plasma conditions produced by pulsed laboratory sources including for example, short and long pulse lasers; pulsed power devices; FELs; XFELs and ion beams. The full range of plasma spectroscopy from the optical range up to high energy bremsstrahlung radiation will be covered. The deadline for submitting to this special issue is 1 March 2015. (Expected web publication: autumn 2015). Late submissions will be considered for the journal, but may not be included in the special issue. All submitted articles will be fully refereed to the journal's usual high standards. Upon publication, the issue will be widely promoted to the atomic, molecular and optical physics community, ensuring that your work receives maximum visibility. Articles should be submitted at http://mc04.manuscriptcentral.com/jphysb-iop. Should you have any questions regarding the preparation of manuscripts or the suitability of your work for this Issue, please do not hesitate to contact the J. Phys. B: At. Mol. Opt. Editorial team (jphysb@iop.org). We look forward to hearing from you and hope that we can welcome you as a contributing author.

CALL FOR PAPERS: Special issue on Current Trends in Integrability and Nonlinear Phenomena Special issue on Current Trends in Integrability and Nonlinear Phenomena

Science.gov (United States)

Gómez-Ullate, D.; Lombardo, S.; Mañas, M.; Mazzocco, M.; Nijhoff, F.; Sommacal, M.

2009-12-01

This is a call for contributions to a special issue of Journal of Physics A: Mathematical and Theoretical dedicated to integrability and nonlinear phenomena. The motivation behind this special issue is to summarize in a single comprehensive publication, the main aspects (past and present), latest developments, different viewpoints and the directions being followed in this multidisciplinary field. We hope that such a special issue could become a particularly valuable reference for the broad scientific community working in integrability and nonlinear phenomena. Editorial policy The Editorial Board has invited D Gómez-Ullate, S Lombardo, M Mañas, M Mazzocco, F Nijhoff and M Sommacal to serve as Guest Editors for the special issue. Their criteria for the acceptance of contributions are as follows. The subject of the paper should relate to the following list of subjects: Integrable systems (including quantum and discrete) and applications Dynamical systems: Hamiltonian systems and dynamics in the complex domain Nonlinear waves, soliton equations and applications Nonlinear ODEs including Painlevé equations and isomonodromic deformations Symmetries and perturbative methods in the classification of integrable PDEs Infinite dimensional Lie algebras and integrable systems Orthogonal polynomials, random matrix theory All contributions will be refereed and processed according to the usual procedure of the journal. Papers should report original and significant research that has not already been published. Guidelines for preparation of contributions The DEADLINE for contributed papers will be 28 February 2010. This deadline will allow the special issue to appear in October 2010. There is a nominal page limit of 15 printed pages per contribution (invited review papers can be longer). For papers exceeding this limit, the Guest Editors reserve the right to request a reduction in length. Further advice on publishing your work in Journal of Physics A: Mathematical and Theoretical

Introduction to special issue: moving forward in pediatric neuropsychology.

Science.gov (United States)

Daly, Brian P; Giovannetti, Tania; Zabel, T Andrew; Chute, Douglas L

2011-08-01

This special issue of The Clinical Neuropsychologist focuses on advances in the emerging subspecialty of pediatric neuropsychology. The national and international contributions in this issue cover a range of key clinical, research, training, and professional issues specific to pediatric neuropsychology. The genesis for this project developed out of a series of talks at the Philadelphia Pediatric Neuropsychology Symposium in 2010, hosted by the Stein Family Fellow, the Department of Psychology of the College of Arts and Sciences at Drexel University, and the Philadelphia Neuropsychology Society. Articles that explore clinical practice issue focus on the assessment of special medical populations with congenital and/or acquired central nervous system insults. Research articles investigate the core features of developmental conditions, the use of technology in neuropsychological research studies, and large sample size genomic, neuropsychological, and imaging studies of under-represented populations. The final series of articles examine new considerations in training, advocacy, and subspecialty board certification that have emerged in pediatric neuropsychology. This introductory article provides an overview of the articles in this special issue and concluding thoughts about the future of pediatric neuropsychology.

Special Issue on Creativity at Work.

Science.gov (United States)

Donnelly, Brian; And Others

1994-01-01

Special issue includes "Creativity at the Workplace" (Donnelly); "Creativity Revisited" (Iandoli); interviews with 16 people who work in or teach industrial engineering, software, and graphic design; "On Creativity and Schooling" (Coppola, Iandoli); and "End Notes: What I Learned" (Iandoli). (SK)

Placing the special trains issue in perspective

International Nuclear Information System (INIS)

Rhoads, R.E.; DeSteese, J.G.; Loscutoff, W.V.; Chais, M.

1978-01-01

The Association of American Railroads has proposed changes in the way railroads handle shipments of radioactive materials. These changes are embodied in a set of recommended operating practices that would require shipments of spent fuel and radioactive waste to be moved only in special train service. The proposed operating practices include a 35 mph maximum speed restriction, a passing restriction and a no-other freight restriction. Shippers of radioactive materials oppose the imposition of these operating practices. The special train issue is currently being argued in hearings before the Interstate Commerce Commission. The history and current status of these hearings are reviewed. Pacific Northwest Laboratories has undertaken a study to provide perspective on the safety and economic factors related to the use of special trains for shipping spent fuel. The results of this study for the amount of spent fuel anticipated to be shipped in 1986 are reviewed. The safety analysis determines the frequencies and severities of accidents for conventional freight trains and compares these to extrapolated frequencies and severities of accidents for conventional freight trains subject to the special train operating restrictions. Results of the study show that the adoption of special trains and attendant operating restrictions has limited potential for improving safety during shipment. The economic analysis compares the cost of spent fuel shipments made by special train and by conventional freight train service.Results of the economics phase of the study show that the use of special trains will most likely increase the cost of shipments by about 50%, although under certain circumstances shipping costs for spent fuel by special trains may be up to 20% lower than by conventional train service. Possible methods to resolve the special train issue are explored

In silico toxicology for the pharmaceutical sciences

International Nuclear Information System (INIS)

Valerio, Luis G.

2009-01-01

The applied use of in silico technologies (a.k.a. computational toxicology, in silico toxicology, computer-assisted tox, e-tox, i-drug discovery, predictive ADME, etc.) for predicting preclinical toxicological endpoints, clinical adverse effects, and metabolism of pharmaceutical substances has become of high interest to the scientific community and the public. The increased accessibility of these technologies for scientists and recent regulations permitting their use for chemical risk assessment supports this notion. The scientific community is interested in the appropriate use of such technologies as a tool to enhance product development and safety of pharmaceuticals and other xenobiotics, while ensuring the reliability and accuracy of in silico approaches for the toxicological and pharmacological sciences. For pharmaceutical substances, this means active and impurity chemicals in the drug product may be screened using specialized software and databases designed to cover these substances through a chemical structure-based screening process and algorithm specific to a given software program. A major goal for use of these software programs is to enable industry scientists not only to enhance the discovery process but also to ensure the judicious use of in silico tools to support risk assessments of drug-induced toxicities and in safety evaluations. However, a great amount of applied research is still needed, and there are many limitations with these approaches which are described in this review. Currently, there is a wide range of endpoints available from predictive quantitative structure-activity relationship models driven by many different computational software programs and data sources, and this is only expected to grow. For example, there are models based on non-proprietary and/or proprietary information specific to assessing potential rodent carcinogenicity, in silico screens for ICH genetic toxicity assays, reproductive and developmental toxicity, theoretical

Special Issue on Using Econometrics for Assessing Economic Models

DEFF Research Database (Denmark)

Juselius, Katarina

2009-01-01

Two methodological approaches to empirical economics which are labelled ‘theory first' versus ‘reality first' are introduced building the background for the discussion of the individual contributions to this special issue.......Two methodological approaches to empirical economics which are labelled ‘theory first' versus ‘reality first' are introduced building the background for the discussion of the individual contributions to this special issue....

Editorial of the Special Issue Antimicrobial Polymers

Directory of Open Access Journals (Sweden)

Iolanda Francolini

2013-09-01

Full Text Available The special issue “Antimicrobial Polymers” includes research and review papers concerning the recent advances on preparation of antimicrobial polymers and their relevance to industrial settings and biomedical field. Antimicrobial polymers have recently emerged as promising candidates to fight microbial contamination onto surfaces thanks to their interesting properties. In this special issue, the main strategies pursued for developing antimicrobial polymers, including polymer impregnation with antimicrobial agents or synthesis of polymers bearing antimicrobial moieties, were discussed. The future application of these polymers either in industrial or healthcare settings could result in an extremely positive impact not only at the economic level but also for the improvement of quality of life.

Special issue on Computational Neuroscience - PREFACE

DEFF Research Database (Denmark)

Ditlevsen, Susanne; Lansky, Petr

2014-01-01

This Special Issue of Mathematical Biosciences and Engineering contains ten selected papers presented at the Neural Coding 2012 workshop. Neuroscience is traditionally very close to mathematics which stems from the famous theoretical work of McCulloch--Pitts and Hodgkin--Huxley in the middle...

A special issue on solar cells

Institute of Scientific and Technical Information of China (English)

Yi-Bing CHENG

2011-01-01

@@ The increasing demand for renewable energy has made the solar cell technology as one of the most significantresearch and development areas of today.Silicon based solar cells are the dominant photovoltaic products at the present time, but the relatively high costs are barriers for their broad applications.Research has been active worldwide in developing other photovoltaic technologies that use cheap materials and can be easily manufactured.Organic solar cells have attracted a lot of interests recently due to their potential to be low cost photovoltaic technologies.This special issue of the Frontiers of Optoelectronics in China has collected research articles by a number of Chinese and international experts.It is aimed to broaden the readers' view about some of the recent developments and challenges in this important R&D field.Thirteen excellent papers are in this special issue including 4 review articles and 9 research articles.

Shuttle Lesson Learned - Toxicology

Science.gov (United States)

James, John T.

2010-01-01

This is a script for a video about toxicology and the space shuttle. The first segment is deals with dust in the space vehicle. The next segment will be about archival samples. Then we'll look at real time on-board analyzers that give us a lot of capability in terms of monitoring for combustion products and the ability to monitor volatile organics on the station. Finally we will look at other issues that are about setting limits and dealing with ground based lessons that pertain to toxicology.

Introduction to the special issue

Directory of Open Access Journals (Sweden)

Gisela Boehm

2008-01-01

Full Text Available (from the introduction Intuition and affect have been neglected topics in the literature on human judgment and decision making for a long time. Judgmental processes involved in risk perception and decision making have traditionally been conceptualized as cognitive in nature, being based upon a rational and deliberate evaluation of the alternatives at hand. This picture started to change in the early 1980s when decision researchers looked beyond rational, deliberate, and cognitive processes and began to investigate intuitive --- as opposed to deliberate --- and emotional --- as opposed to cognitive --- aspects of decision making. In sum, decision research has seen a proliferation of approaches that look beyond rational, deliberate, and purely cognitive processes in decision making and investigate intuitive and emotional judgments in this area. This seemed like a good point in time to reflect the state of this emerging field in a special issue that addresses the question of how intuition and affect are related to each other and how they shape risk perception and decision making. This special issue is the result of a workshop that was held at the University of Bergen in November, 2006.

Toxicology research for precautionary decision-making and the role of Human & Experimental Toxicology.

Science.gov (United States)

Grandjean, P

2015-12-01

A key aim of toxicology is the prevention of adverse effects due to toxic hazards. Therefore, the dissemination of toxicology research findings must confront two important challenges: one being the lack of information on the vast majority of potentially toxic industrial chemicals and the other being the strict criteria for scientific proof usually required for decision-making in regard to prevention. The present study ascertains the coverage of environmental chemicals in four volumes of Human & Experimental Toxicology and the presentation and interpretation of research findings in published articles. Links in SciFinder showed that the 530 articles published in four selected volumes between 1984 and 2014 primarily dealt with metals (126 links) and other toxicants that have received substantial attention in the past. Thirteen compounds identified by US authorities in 2006 as high-priority substances, for which toxicology documentation is badly needed, were not covered in the journal issues at all. When reviewing published articles, reliance on p values was standard, and non-significant findings were often called 'negative.' This tradition may contribute to the perceived need to extend existing research on toxic hazards that have already been well characterized. Several sources of bias towards the null hypothesis can affect toxicology research, but are generally not considered, thus adding to the current inclination to avoid false positive findings. In this regard, toxicology is particularly prone to bias because of the known paucity of false positives and, in particular, the existence of a vast number of toxic hazards which by default are considered innocuous due to lack of documentation. The Precautionary Principle could inspire decision-making on the basis of incomplete documentation and should stimulate a change in toxicology traditions and in toxicology research publication. © The Author(s) 2015.

Proceedings of the 2015 National Toxicology Program Satellite Symposium.

Science.gov (United States)

Elmore, Susan A; Farman, Cindy A; Hailey, James R; Kovi, Ramesh C; Malarkey, David E; Morrison, James P; Neel, Jennifer; Pesavento, Patricia A; Porter, Brian F; Szabo, Kathleen A; Teixeira, Leandro B C; Quist, Erin M

2016-06-01

The 2015 Annual National Toxicology Program Satellite Symposium, entitled "Pathology Potpourri" was held in Minneapolis, Minnesota, at the American College of Veterinary Pathologists/American Society for Veterinary Clinical Pathology/Society of Toxicologic Pathology combined meeting. The goal of this symposium is to present and discuss diagnostic pathology challenges or nomenclature issues. Because of the combined meeting, both laboratory and domestic animal cases were presented. This article presents summaries of the speakers' talks, including challenging diagnostic cases or nomenclature issues that were presented, along with select images that were used for audience voting and discussion. Some lesions and topics covered during the symposium included hepatocellular lesions, a proposed harmonized diagnostic approach to rat cardiomyopathy, crop milk in a bird, avian feeding accoutrement, heat exchanger in a tuna, metastasis of a tobacco carcinogen-induced pulmonary carcinoma, neurocytoma in a rat, pituicytoma in a rat, rodent mammary gland whole mounts, dog and rat alveolar macrophage ultrastructure, dog and rat pulmonary phospholipidosis, alveolar macrophage aggregation in a dog, degenerating yeast in a cat liver aspirate, myeloid leukemia in lymph node aspirates from a dog, Trypanosoma cruzi in a dog, solanum toxicity in a cow, bovine astrovirus, malignant microglial tumor, and nomenclature challenges from the Special Senses International Harmonization of Nomenclature and Diagnostic Criteria Organ Working Group. © The Author(s) 2016.

Special Issues for People with Aplastic Anemia

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... Menu Donate Special Issues for People with Aplastic Anemia Because you have aplastic anemia , everyday events can ... bleeding, such as contact sports. Pregnancy and Aplastic Anemia Pregnancy is possible for women who have been ...

Understanding Game-Based Learning Cultures: Introduction to Special Issue

Science.gov (United States)

Engerman, Jason A.; Carr-Chellman, Alison

2017-01-01

This special issue expands our understanding of teaching and learning through video game play, with specific attention to culture. The issue gives insight into the ways educators, researchers, and developers should be discussing and designing for impactful learner-centered game-based learning experiences. The issue features forward-thinking…

Crustal permeability: Introduction to the special issue

Science.gov (United States)

Ingebritsen, Steven E.; Gleeson, Tom

2015-01-01

The topic of crustal permeability is of broad interest in light of the controlling effect of permeability on diverse geologic processes and also timely in light of the practical challenges associated with emerging technologies such as hydraulic fracturing for oil and gas production (‘fracking’), enhanced geothermal systems, and geologic carbon sequestration. This special issue of Geofluids is also motivated by the historical dichotomy between the hydrogeologic concept of permeability as a static material property that exerts control on fluid flow and the perspective of economic geologists, geophysicists, and crustal petrologists who have long recognized permeability as a dynamic parameter that changes in response to tectonism, fluid production, and geochemical reactions. Issues associated with fracking, enhanced geothermal systems, and geologic carbon sequestration have already begun to promote a constructive dialog between the static and dynamic views of permeability, and here we have made a conscious effort to include both viewpoints. This special issue also focuses on the quantification of permeability, encompassing both direct measurement of permeability in the uppermost crust and inferential permeability estimates, mainly for the deeper crust.

Special Issue ;Sediment cascades in cold climate geosystems;

Science.gov (United States)

Morche, David; Krautblatter, Michael; Beylich, Achim A.

2017-06-01

This Editorial introduces the Special Issue on sediment cascades in cold climate geosystems that evolved from the eighth I.A.G./A.I.G. SEDIBUD (Sediment Budgets in Cold Environments; http://www.geomorph.org/sedibud-working-group/) workshop. The workshop was held from 1st to 4th September 2014 at the Environmental Research Station ;Schneefernerhaus; (http://www.schneefernerhaus.de/en/home.html) located at Mt. Zugspitze, the highest peak of Germany, (2962 m asl). Paper and poster presentations focused on observations, measurements and modeling of geomorphological processes in sediment cascades in cold climate geosystems. This resulting Special Issue brings together ten selected contributions from arctic and alpine environments.

Aerospace Toxicology and Microbiology

Science.gov (United States)

James, John T.; Parmet, A. J.; Pierson, Duane L.

2007-01-01

Toxicology dates to the very earliest history of humanity with various poisons and venom being recognized as a method of hunting or waging war with the earliest documentation in the Evers papyrus (circa 1500 BCE). The Greeks identified specific poisons such as hemlock, a method of state execution, and the Greek word toxos (arrow) became the root of our modern science. The first scientific approach to the understanding of poisons and toxicology was the work during the late middle ages of Paracelsus. He formulated what were then revolutionary views that a specific toxic agent or "toxicon" caused specific dose-related effects. His principles have established the basis of modern pharmacology and toxicology. In 1700, Bernardo Ramazzini published the book De Morbis Artificum Diatriba (The Diseases of Workers) describing specific illnesses associated with certain labor, particularly metal workers exposed to mercury, lead, arsenic, and rock dust. Modern toxicology dates from development of the modern industrial chemical processes, the earliest involving an analytical method for arsenic by Marsh in 1836. Industrial organic chemicals were synthesized in the late 1800 s along with anesthetics and disinfectants. In 1908, Hamilton began the long study of occupational toxicology issues, and by WW I the scientific use of toxicants saw Haber creating war gases and defining time-dosage relationships that are used even today.

Special issue dedicated to Professor Johann M. Schepers

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Gideon P De Bruin

2006-10-01

Full Text Available It is a great pleasure for me to have been associated with this special issue of the SA Journal of Industrial Psychology dedicated to Professor Johann M. Schepers. The purpose of the special issue is to honour Professor Schepers for his contributions to the development of Psychology and Industrial Psychology as empirical fields of study in South Africa. The contributors have worked with Professor Schepers as students or colleagues and share his academic interests. The articles reflect his areas of interest and employ analytic techniques taught and championed by him. We are grateful to Professor Schepers for his cooperation throughout this project. Thanks are due to all the contributors and referees.

Diversification in toxicology: man and environment. EUROTOX proceedings

Energy Technology Data Exchange (ETDEWEB)

Seiler, J.P. [Intercantonal Office for the Control of Medicines (IOCM), Bern (Switzerland); Autrup, J.L.; Autrup, H. [eds.] [Aarhus Univ. (Denmark). Steno Inst. of Public Health

1998-12-31

This volume contains the main papers presented at the 1997 EUROTOX Congress, Aaarhus, Denmark, 24-28 June 1997. Diversification in toxicology is not seen as splitting into subfields, but as the application of basic science to such diverse areas as man and his environment. The pressing issues which have been dealt with not only include reproductive effects of environmental chemicals (`xenoestrogens`), but also receptor-mediated toxic responses, new frontiers in human and ecological toxicology, chemoprevention of cancer and molecular approaches in toxicological research. The practical and ethical facets of toxicology, e.g. ecotoxicological risk assessment, biomarkers of exposure, complex chemical mixtures as well as animal welfare and the ethics of animal experimentation, are also treated. (orig.)

Special Issue: Competencies from the Individual's Viewpoint.

Science.gov (United States)

Career Planning and Adult Development Journal, 2003

2003-01-01

Ten articles in this special issue deal with competencies and how their use is revolutionizing human resource management and the work of career practitioners. Topics include competency technology, models, and mapping; behavioral interviewing; talent management; emotional intelligence; succession planning; and lifelong learning. (JOW)

Special Issue: Productive Employment for the Poor.

Science.gov (United States)

Gaude, Jacques, Ed.; Miller, Steven, Ed.

1992-01-01

This special issue contains nine articles on labor-intensive public works, social investment funds, rural infrastructure projects, grassroots socioeconomic rights, remuneration systems for self-help projects, road construction and rural transport, employment and environmental rehabilitation, and water as a source of employment. (SK)

Evolution of toxicology information systems

Energy Technology Data Exchange (ETDEWEB)

Wassom, J.S.; Lu, P.Y. [Oak Ridge National Laboratory, TN (United States)

1990-12-31

Society today is faced with new health risk situations that have been brought about by recent scientific and technical advances. Federal and state governments are required to assess the many potential health risks to exposed populations from the products (chemicals) and by-products (pollutants) of these advances. Because a sound analysis of any potential health risk should be based on the use of relevant information, it behooves those individuals responsible for making the risk assessments to know where to obtain needed information. This paper reviews the origins of toxicology information systems and explores the specialized information center concept that was proposed in 1963 as a means of providing ready access to scientific and technical information. As a means of illustrating this concept, the operation of one specialized information center (the Environmental Mutagen Information Center at Oak Ridge National Laboratory) will be discussed. Insights into how toxicological information resources came into being, their design and makeup, will be of value to those seeking to acquire information for risk assessment purposes. 7 refs., 1 fig., 4 tabs.

Introduction to 'The Unacceptable' Special Issue

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John Scannell

2015-02-01

Full Text Available This special issue of Portal contends with the 'unacceptable' as the intervention upon bodies, images or practices deemed excessive to the limits of functional community. Under the rubric of propriety, discussion of the 'unacceptable' can all too easily become marginalised through silence, erasure and/or condemnation. Yet challenging the boundaries of the 'unacceptable' is vital to the continuity of a civil society, and the articles contained in this issue attempt to probe the limits of acceptability, as they seek to comprehend, and perhaps, intervene upon some divisive contemporary issues. Torture, disability, sexuality, e-waste, bureaucracy, comedy, and the constitution of the strange are among the broad range of topics in which the definition, regulation and assessment of unacceptability are pursued. Through documentation of such suitably 'unacceptable' issues, the articles contained in this volume not only compel the reader to question convention, but furthermore, interrogate the point where social intervention upon desire might be necessary too. John Scannell, guest editor.

Special issue on activity-travel decision processes

NARCIS (Netherlands)

Doherty, S.; Ettema, D.F.

2006-01-01

Before you lies the 2006 TRB (Transportation Research Board) Special Issue of Transportation comprising selected papers presented at the 2006 Annual Meeting of the TRB in sessions sponsored by the Travel Behavior and Values committee on activity-travel decision processes. We are pleased to serve

Introduction to the special issue on college student mental health.

Science.gov (United States)

Castillo, Linda G; Schwartz, Seth J

2013-04-01

This article provides an introduction to the special issue on college student mental health. It gives an overview of the establishment of the Multi-Site University Study of Identity and Culture (MUSIC) collaborative by a group of national experts on culture and identity. Information about the procedures used to collect a nationally represented sample of college students are provided. Data were collected from 30 university sites across the United States. The sample comprised 10,573 undergraduate college students, of which 73% were women, 63% White, 9% African American/Black, 14% Latino/Hispanic, 13% Asian American, and 1% Other. The special issue comprises a compilation of 8 studies that used the dataset specifically created to examine the issues of emerging adults, culture, and identity. Student mental health problems are a growing concern on college campuses. Studies covered in this special issue have implications for policy development regarding college alcohol use and traumatic victimization, include attention to underrepresented minority and immigrant groups on college campuses, and focus on positive as well as pathological aspects of the college experience. © 2013 Wiley Periodicals, Inc.

"Special Issue": Regional Dimensions of the Triple Helix Model

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Todeva, Emanuela; Danson, Mike

2016-01-01

This paper introduces the rationale for the special issue and its contributions, which bridge the literature on regional development and the Triple Helix model. The concept of the Triple Helix at the sub-national, and specifically regional, level is established and examined, with special regard to regional economic development founded on…

Advancing Toxicology Research Using In Vivo High Throughput Toxicology with Small Fish Models

Science.gov (United States)

Planchart, Antonio; Mattingly, Carolyn J.; Allen, David; Ceger, Patricia; Casey, Warren; Hinton, David; Kanungo, Jyotshna; Kullman, Seth W.; Tal, Tamara; Bondesson, Maria; Burgess, Shawn M.; Sullivan, Con; Kim, Carol; Behl, Mamta; Padilla, Stephanie; Reif, David M.; Tanguay, Robert L.; Hamm, Jon

2017-01-01

Summary Small freshwater fish models, especially zebrafish, offer advantages over traditional rodent models, including low maintenance and husbandry costs, high fecundity, genetic diversity, physiology similar to that of traditional biomedical models, and reduced animal welfare concerns. The Collaborative Workshop on Aquatic Models and 21st Century Toxicology was held at North Carolina State University on May 5-6, 2014, in Raleigh, North Carolina, USA. Participants discussed the ways in which small fish are being used as models to screen toxicants and understand mechanisms of toxicity. Workshop participants agreed that the lack of standardized protocols is an impediment to broader acceptance of these models, whereas development of standardized protocols, validation, and subsequent regulatory acceptance would facilitate greater usage. Given the advantages and increasing application of small fish models, there was widespread interest in follow-up workshops to review and discuss developments in their use. In this article, we summarize the recommendations formulated by workshop participants to enhance the utility of small fish species in toxicology studies, as well as many of the advances in the field of toxicology that resulted from using small fish species, including advances in developmental toxicology, cardiovascular toxicology, neurotoxicology, and immunotoxicology. We also review many emerging issues that will benefit from using small fish species, especially zebrafish, and new technologies that will enable using these organisms to yield results unprecedented in their information content to better understand how toxicants affect development and health. PMID:27328013

EDITORIAL: Special issue on Graphene Special issue on Graphene

Science.gov (United States)

Morpurgo, Alberto F.; Trauzettel, Björn

2010-03-01

Since the revolutionary experimental discovery of graphene in the year 2004, research on this new two-dimensional carbon allotrope has progressed at a spectacular pace. The impact of graphene on different areas of research— including physics, chemistry, and applied sciences— is only now starting to be fully appreciated. There are different factors that make graphene a truly impressive system. Regarding nano-electronics and related fields, for instance, it is the exceptional electronic and mechanical properties that yield very high room-temperature mobility values, due to the particular band structure, the material `cleanliness' (very low-concentration of impurities), as well as its stiffness. Also interesting is the possibility to have a high electrical conductivity and optical transparency, a combination which cannot be easily found in other material systems. For other fields, other properties could be mentioned, many of which are currently being explored. In the first years following this discovery, research on graphene has mainly focused on the fundamental physics aspects, triggered by the fact that electrons in graphene behave as Dirac fermions due to their interaction with the ions of the honeycomb lattice. This direction has led to the discovery of new phenomena such as Klein tunneling in a solid state system and the so-called half-integer quantum Hall effect due to a special type of Berry phase that appears in graphene. It has also led to the appreciation of thicker layers of graphene, which also have outstanding new properties of great interest in their own right (e.g., bilayer graphene, which supports chiral quasiparticles that, contrary to Dirac electrons, are not massless). Now the time is coming to deepen our knowledge and improve our control of the material properties, which is a key aspect to take one step further towards applications. The articles in the Semiconductor Science and Technology Graphene special issue deal with a diversity of topics

Veterinary Forensic Toxicology.

Science.gov (United States)

Gwaltney-Brant, S M

2016-09-01

Veterinary pathologists working in diagnostic laboratories are sometimes presented with cases involving animal poisonings that become the object of criminal or civil litigation. Forensic veterinary toxicology cases can include cases involving animal cruelty (malicious poisoning), regulatory issues (eg, contamination of the food supply), insurance litigation, or poisoning of wildlife. An understanding of the appropriate approach to these types of cases, including proper sample collection, handling, and transport, is essential so that chain of custody rules are followed and proper samples are obtained for toxicological analysis. Consultation with veterinary toxicologists at the diagnostic laboratory that will be processing the samples before, during, and after the forensic necropsy can help to ensure that the analytical tests performed are appropriate for the circumstances and findings surrounding the individual case. © The Author(s) 2016.

Introduction - AABFJ Financial Planning Special Issue 2009

Directory of Open Access Journals (Sweden)

Ciorstan J. Smark

2009-03-01

Full Text Available This special issue draws on recent work of financial planning specialists, finance specialists and economists todocument some of the trends, perception and challenges of financial planning in 2009. This diversity ofcontributors reflects the diversity and the multiplicity of influences that impact on financial planning.

Finally Making Good on the Promise of Qualitative Research in Special Education? A Response to the Special Issue

Science.gov (United States)

Pugach, Marleen C.; Mukhopadhyay, Ananya; Gomez-Najarro, Joyce

2014-01-01

In this response to the special issue, we would like to offer two additional considerations to the discourse on qualitative research and special education this issue is meant to catalyze. First, we would like to further problematize the question of why qualitative research continues to be so sparsely represented in most prominent publications of…

Scientific uncertainty in media content: Introduction to this special issue.

Science.gov (United States)

Peters, Hans Peter; Dunwoody, Sharon

2016-11-01

This introduction sets the stage for the special issue on the public communication of scientific uncertainty that follows by sketching the wider landscape of issues related to the communication of uncertainty and showing how the individual contributions fit into that landscape. The first part of the introduction discusses the creation of media content as a process involving journalists, scientific sources, stakeholders, and the responsive audience. The second part then provides an overview of the perception of scientific uncertainty presented by the media and the consequences for the recipients' own assessments of uncertainty. Finally, we briefly describe the six research articles included in this special issue. © The Author(s) 2016.

Two-Beam Linear Colliders - Special Issues

CERN Document Server

Corsini, Roberto

2010-01-01

The path towards a multi-TeV e+e- linear collider proposed by the CLIC study is based on the Two-Beam Acceleration (TBA) scheme. Such a scheme is promising in term of efficiency, reliability and cost. The rationale behind the two-beam scheme is discussed in the paper, together with the special issues related to this technology and the R&D needed to demonstrate its feasibility.

FOREWORD: Special issue on density

Science.gov (United States)

Fujii, Kenichi

2004-04-01

This special issue on density was undertaken to provide readers with an overview of the present state of the density standards for solids, liquids and gases, as well as the technologies developed for measuring density. This issue also includes topics on the refractive index of gases and on techniques used for calibrating hydrometers so that almost all areas concerned with density standards are covered in four review articles and seven original articles, most of which describe current research being conducted at national metrology institutes (NMIs). A review article was invited from the Ruhr-Universität Bochum to highlight research on the magnetic suspension densimeters. In metrology, the determinations of the volume of a weight and the density of air are of primary importance in establishing a mass standard because the effect of the buoyancy force of air acting on the weight must be known accurately to determine the mass of the weight. A density standard has therefore been developed at many NMIs with a close relation to the mass standard. Hydrostatic weighing is widely used to measure the volume of a solid. The most conventional hydrostatic weighing method uses water as a primary density standard for measuring the volume of a solid. A brief history of the determination of the density of water is therefore given in a review article, as well as a recommended value for the density of water with a specified isotopic abundance. The most modern technique for hydrostatic weighing uses a solid density standard instead of water. For this purpose, optical interferometers for measuring the diameters of silicon spheres have been developed to convert the length standard into the volume standard with a small uncertainty. A review article is therefore dedicated to describing the state-of-the-art optical interferometers developed for silicon spheres. Relative combined standard uncertainties of several parts in 108 have been achieved today for measuring the volume and density of

Special journal issue highlights IDRC-supported findings on ...

International Development Research Centre (IDRC) Digital Library (Canada)

2018-03-08

Mar 8, 2018 ... Special journal issue highlights IDRC-supported findings on women's paid work ... An important aspect of women's economic empowerment is their participation in the labour ... Maternal health research concerns men too.

Energy, a crucial environmental subject. Special issue

International Nuclear Information System (INIS)

2001-01-01

In this issue of the magazine ArenA special attention is paid the use of energy in the Netherlands, the related problems and solutions, and the agenda for the Section Energy of the Dutch Association of Environmental Professionals (VVM) resulting from the technological, administrative and economical problems and solutions

From the Editors of the Special Issue

NARCIS (Netherlands)

Ruttkay, Z.M.; Kipp, Michael; Kipp, M.; Nijholt, Antinus; Vilhjálmsson, H.H.; Vilhjalmsson, Högni

2010-01-01

Welcome to the special issue on Intelligent Virtual Agents. Intelligent Virtual Agents (IVAs) are interactive characters that – in spite of being merely 2D or 3D computer graphics models – exhibit humanlike qualities and communicate with humans or with each other using natural human modalities such

JGR special issue on Deep Earthquakes

Science.gov (United States)

The editor and associate editors of the Journal of Geophysical Research—Solid Earth and Planets invite the submission of manuscripts for a special issue on the topic “Deep- and Intermediate-Focus Earthquakes, Phase Transitions, and the Mechanics of Deep Subduction.”Manuscripts should be submitted to JGR Editor Gerald Schubert (Department of Earth and Space Sciences, University of California, Los Angeles, Los Angeles, CA 90024) before July 1, 1986, in accordance with the usual rules for manuscript submission. Submitted papers will undergo the normal JGR review procedure. For more information, contact either Schubert or the special guest associate editor, Cliff Frohlich (Institute for Geophysics, University of Texas at Austin, 4920 North IH-35, Austin, TX 78751; telephone: 512-451-6223).

Resonance Special Issue - World Year of Physics -RE ...

Indian Academy of Sciences (India)

Resonance Special Issue - World Year of Physics. Vol 10, No 12, ... Origin (?) of the Universe - The Expanding Universe. Jayant V Narlikar. 12 ... Einstein's Last Dream: The Space - Time Unification of Fundamental Forces. Abdus Salam.

Special issue introduction: Ecological modernization

DEFF Research Database (Denmark)

Massa, Ilmo; Andersen, Mikael Skou

2000-01-01

The contributions to this special issue of the Journal of Environmental Policy and Planning stem from an international conference on ecological modernization that took place at the Department of Social Policy of the University of Helsinki, Finland, in late 1998. They have been selected, among other...... reasons, for their possible contribution to conceptual understanding and clarification. While recent publications have explored the implications of ecological modernization in different settings (Mol & Sonnenfeld, 2000), here we try to put the concept under the microscope again, in the hope of clarifying...

Attachment-related mental representations: introduction to the special issue.

Science.gov (United States)

Thompson, Ross A

2008-12-01

Bowlby's concept of mental working models of self, attachment figures, and the social world has been theoretically generative as a bridge between early relational experience and the beliefs and expectations that color later relationships. Contemporary attachment researchers, following his example, are applying new knowledge of children's conceptual development to their study of attachment-related mental representations in children and adults. The contributors to this special issue highlight recent advances in how the mental representations arising from attachment security should be conceptualized and studied, and identify a number of important directions for future work. This paper introduces the special issue by summarizing the major ideas of Bowlby and his followers concerning the nature and development of mental working models, points of theoretical clarity and uncertainty, and challenges in assessing these representations, as well as profiling each of the contributions to this issue.

Special issue: Logistics systems design in Latin America

Directory of Open Access Journals (Sweden)

Miguel Gaston Cedillo Campos

2017-10-01

Under this context, this Special Issue of the Journal of Industrial Engineering and Management (JIEM gathers nine significant contributions, which from a Latin American approach, enhance the logistics systems body of knowledge focused on emerging markets.

Special issue on network coding

Science.gov (United States)

Monteiro, Francisco A.; Burr, Alister; Chatzigeorgiou, Ioannis; Hollanti, Camilla; Krikidis, Ioannis; Seferoglu, Hulya; Skachek, Vitaly

2017-12-01

Future networks are expected to depart from traditional routing schemes in order to embrace network coding (NC)-based schemes. These have created a lot of interest both in academia and industry in recent years. Under the NC paradigm, symbols are transported through the network by combining several information streams originating from the same or different sources. This special issue contains thirteen papers, some dealing with design aspects of NC and related concepts (e.g., fountain codes) and some showcasing the application of NC to new services and technologies, such as data multi-view streaming of video or underwater sensor networks. One can find papers that show how NC turns data transmission more robust to packet losses, faster to decode, and more resilient to network changes, such as dynamic topologies and different user options, and how NC can improve the overall throughput. This issue also includes papers showing that NC principles can be used at different layers of the networks (including the physical layer) and how the same fundamental principles can lead to new distributed storage systems. Some of the papers in this issue have a theoretical nature, including code design, while others describe hardware testbeds and prototypes.

Introduction to the special issue: permafrost and periglacial research from coasts to mountains

Science.gov (United States)

Schrott, Lothar; Humlum, Ole

2017-09-01

This special issue of Geomorphology includes eleven papers dealing with permafrost and periglacial research from coasts to mountains. The compilation represents a selection from 47 presentations (oral and posters) given at the 4th European Conference on Permafrost - IPA Regional Conference (EUCOP4, June 2014) in the session ;Periglacial Geomorphology;. Geomorphology as a leading journal for our discipline is particularly suitable to publish advances in permafrost and periglacial research with a focus on geomorphic processes. Since 1989 Geomorphology has published 121 special issues and two special issues are explicitly dedicated to permafrost and periglacial research, however, only with a focus on research in Antarctica. In this special issue we present papers from the Canadian Beaufort Sea, Alaska, Spitzbergen, central western Poland, the European Alps, the eastern Sudetes, the southern Carpathians, Nepal, and Antarctica.

A Helicopter View of the Special Issue on Wave Energy Converters

Directory of Open Access Journals (Sweden)

Diego Vicinanza

2017-02-01

Full Text Available This paper intends to provide the reader with an overview of the Special Issue on Wave Energy Converters. Through 16 contributions from authors of 10 different countries, a number of key topics have been tackled, including resource assessment, engineering design, and financial analysis. As a whole, the Special Issue forms an interesting and helpful compendium on the state of the art of wave energy extraction and exploitation.

Application of DNA Profiling in Resolving Aviation Forensic Toxicology Issues

Science.gov (United States)

2009-10-01

muscle,.spleen,.and.vitreous.fluid Toxicological Findings Pilot: Carboxyhemoglobin .20% Cyanide.1 .80.µg/mL.in.blood Diphenhydramine.0 .030.µg/mL.in.blood...Diphenhydramine.present.in.liver Copilot: Carboxyhemoglobin .25% Cyanide.2 .07.µg/mL.in.blood Diphenhydramine.0 .036.µg/mL.in.blood

Editorial to the Special issue of the journal

Directory of Open Access Journals (Sweden)

Nikša Alfirević

2016-01-01

Full Text Available This is the editorial to the Special issue of the Management journal, dedicated to the 11th International Conference on "Challenges of Europe", organized by the Faculty of Economics in Split, Croatia, in May 2015.

Special issue “International Geomagnetic Reference Field—the twelfth generation”

DEFF Research Database (Denmark)

Thébault, E.; Finlay, C. C.; Toh, H.

2015-01-01

This special issue of Earth, Planets and Space, synthesizes the efforts made during the construction of the twelfth generation of the International Geomagnetic Reference Field (IGRF-12) that was released online in December 2014 (http://www.ngdc.noaa.gov/IAGA/vmod/ igrf.html). The IGRF-12 is a ser......This special issue of Earth, Planets and Space, synthesizes the efforts made during the construction of the twelfth generation of the International Geomagnetic Reference Field (IGRF-12) that was released online in December 2014 (http://www.ngdc.noaa.gov/IAGA/vmod/ igrf.html). The IGRF-12...

Special Issue on Time Scale Algorithms

Science.gov (United States)

2008-01-01

unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 IOP PUBLISHING METROLOGIA Metrologia 45 (2008) doi:10.1088/0026-1394/45/6/E01...special issue of Metrologia presents selected papers from the Fifth International Time Scale Algorithm Symposium (VITSAS), including some of the...scientists, and hosted by the Real Instituto y Observatorio de la Armada (ROA) in San Fernando, Spain, whose staff further enhanced their nation’s high

Special Issue “Biomaterials and Bioprinting”

Directory of Open Access Journals (Sweden)

Chee Kai Chua

2016-09-01

Full Text Available The emergence of bioprinting in recent years represents a marvellous advancement in 3D printing technology. It expands the range of 3D printable materials from the world of non-living materials into the world of living materials. Biomaterials play an important role in this paradigm shift. This Special Issue focuses on biomaterials and bioprinting and contains eight articles covering a number of recent topics in this emerging area.

Special issue: the nuclear industry in Europe

International Nuclear Information System (INIS)

Anon.

1982-01-01

This special issue contains papers on the following topics: French nuclear policy; nuclear energy development in Europe; nuclear diversification; Alsthom-Atlantique in the nuclear field; 1981 nuclear electricity generation; EDF siting policy; the N4 model of the 1300 MW series; Creys-Malville; the nuclear industry in Europe; pumps in the nuclear industry [fr

Special issue: Supply chain and logistics decisions under environmental aspect

Directory of Open Access Journals (Sweden)

Neslihan Demirel

2017-05-01

Full Text Available This editor’s note has a twofold objective: (1 to present a brief summary about the environmental issues in supply chain and logistics decisions (2 to present general information about the papers published in the special issue.

Special issue : transport in a post-carbon society

Science.gov (United States)

2009-04-01

This special issue of World Transport Policy & Practice is an outcome of the conference Planning for the Carbon Neutral World: Challenges for Cities and Regions, held 15-18 May 2008 in Salzburg, Austria. The conference, organised by SCUPAD Salzbu...

Innovations in Play Therapy: Issues, Process, and Special Populations.

Science.gov (United States)

Landreth, Garry L., Ed.

This book is a compilation of discussions on current issues in play therapy. It is designed to help therapists fill in the gaps about working with special populations, which is often not directly addressed in other play therapy resources. The object of the book is to bring together information related to issues and dynamics of the process of this…

Special Issue on Intelligent Robots

Directory of Open Access Journals (Sweden)

Genci Capi

2013-08-01

Full Text Available The research on intelligent robots will produce robots that are able to operate in everyday life environments, to adapt their program according to environment changes, and to cooperate with other team members and humans. Operating in human environments, robots need to process, in real time, a large amount of sensory data—such as vision, laser, microphone—in order to determine the best action. Intelligent algorithms have been successfully applied to link complex sensory data to robot action. This editorial briefly summarizes recent findings in the field of intelligent robots as described in the articles published in this special issue.

Introduction to the Special Issue: Coastal GIS

Directory of Open Access Journals (Sweden)

Timothy Nyerges

2014-09-01

Full Text Available This special issue of the ISPRS International Journal of Geographic Information about “Coastal GIS” is motivated by many circumstances. More than one-half of the world’s human population lives in coastal areas (within 200 kilometers of coast as of 2000 [1]. The trend toward coastal habitation is expected to continue in the US with the total being 75 percent by 2025, meaning that coastal human–environment interactions will likely increase and intensify [2]. Geographic information systems (GIS are being developed and used by technical specialists, stakeholder publics, and executive/policy decision makers for improving our understanding and management of coastal areas, separately and together as more organizations focus on improving the sustainability and resilience of coastal systems. Coastal systems—defined as the area of land closely connected to the sea, including barrier islands, wetlands, mudflats, beaches, estuaries, cities, towns, recreational areas, and maritime facilities, the continental seas and shelves, and the overlying atmosphere—are subject to complex and dynamic interactions among natural and human-driven processes. Coastal systems are crucial to regional and national economies, hosting valued human-built infrastructure and providing ecosystem services that sustain human well-being. This special issue of IJGI about coastal GIS presents a collection of nine papers that address many of the issues mentioned above. [...

Special Issue: Design and Engineering of Microreactor and Smart-Scaled Flow Processes

Directory of Open Access Journals (Sweden)

Volker Hessel

2014-12-01

Full Text Available Reaction-oriented research in flow chemistry and microreactor has been extensively focused upon in special journal issues and books. On a process level, this resembled the “drop-in” (retrofit concept with the microreactor replacing a conventional (batch reactor. Meanwhile, with the introduction of the mobile, compact, modular container technology, the focus is more on the process side, including also providing an end-to-end vision of intensified process design. Exactly this is the focus of the current special issue “Design and Engineering of Microreactor and Smart-Scaled Flow Processes” of the journal “Processes”. This special issue comprises three review papers, five research articles and two communications. [...

Forensic toxicology in drug-facilitated sexual assault.

Science.gov (United States)

Dinis-Oliveira, Ricardo Jorge; Magalhães, Teresa

2013-09-01

The low rates of reporting, prosecution and conviction that characterize sexual assault, is likely even more evident in drug-facilitated cases. Typically, in these crimes, victims are incapacitated and left unable to resist sexual advances, unconscious, unable to fight off the abuser or to say "no" and unable to clearly remember the circumstances surrounding the events due to anterograde amnesia. The consequence is the delay in performing toxicological analysis aggravated by the reluctance of the victim to disclose the crime. Moreover since "date rape drugs" are often consumed with ethanol and exhibit similar toxicodynamic effects, the diagnosis is erroneously performed as being classical ethanol intoxication. Therefore, it is imperative to rapidly consider toxicological analysis in drug-facilitated sexual assaults. The major focus of this review is to harmonize practical approaches and guidelines to rapidly uncover drug-facilitated sexual assault, namely issues related to when to perform toxicological analysis, toxicological requests, samples to be collected, storage, preservation and transport precautions and xenobiotics or endobiotics to be analyzed.

Juvenile Toxicology: Relevance and Challenges for Toxicologists and Pathologists

Science.gov (United States)

Remick, Amera K.; Catlin, Natasha R.; Quist, Erin M.; Steinbach, Thomas J.; Dixon, Darlene

2015-01-01

The Society of Toxicologic Pathology (STP) Education Committee and the STP Reproductive Special Interest Group held a North Carolina regional meeting entitled, “Juvenile Toxicology: Relevance and Challenges for Toxicologists and Pathologists” on March 13, 2015, at the National Institute of Environmental Health Sciences/National Toxicology Program in Research Triangle Park, North Carolina. The purpose of this regional meeting was to familiarize attendees with the topic of juvenile toxicity testing and discuss its relevance to clinical pediatric medicine, regulatory perspectives, challenges of appropriate study design confronted by toxicologists, and challenges of histopathologic examination and interpretation of juvenile tissues faced by pathologists. The 1-day meeting was a success with over 60 attendees representing industry, government, research organizations, and academia. PMID:26220944

Toxicological Problems with the Redy System

DEFF Research Database (Denmark)

Broch Møller, B.; Bahnsen, M.; Solgaard, Per Bent

1976-01-01

be substituted by another antiseptic. Of special interest was the finding of a very high concentration of boron in the dialysate. It is suggested that this metal, which is a potentially toxic substance, may emanate from the patient. It is concluded that use of the REDY system carries no obvious toxicological......Dialysate from the REDY dialysis system was examined for toxic elements, special attention being paid to the content of zirconium and aluminium. Also investigated was the concentration of formaldehyde in the rinsing fluid of three consecutive washings. The amount of zirconium and aluminium found...

Special Issue of Selected Papers from Visualization and Data Analysis 2011

Science.gov (United States)

Kao, David L.; Wong, Pak Chung

2012-01-01

This special issue features the best papers that were selected from the 18th SPIE Conference on Visualization and Data Analysis (VDA 2011). This annual conference is a major international forum for researchers and practitioners interested in data visualization and analytics research, development, and applications. VDA 2011 received 42 high-quality submissions from around the world. Twenty-four papers were selected for full conference papers. The top five papers have been expanded and reviewed for this special issue.

Special issue: diagnostics of atmospheric pressure microplasmas

Science.gov (United States)

Bruggeman, Peter; Czarnetzki, Uwe; Tachibana, Kunihide

2013-11-01

In recent decades, a strong revival of non-equilibrium atmospheric pressure plasma studies has developed in the form of microplasmas. Microplasmas have typical scales of 1 mm or less and offer a very exciting research direction in the field of plasma science and technology as the discharge physics can be considerably different due to high collisionality and the importance of plasma-surface interaction. These high-pressure small-scale plasmas have a diverse range of physical and chemical properties. This diversity coincides with various applications including light/UV sources [1], material processing [2], chemical analysis [3], material synthesis [4], electromagnetics [5], combustion [6] and even medicine [7]. At atmospheric pressure, large scale plasmas have the tendency to become unstable due to the high collision rates leading to enhanced heating and ionization compared to their low-pressure counterparts. As low-pressure plasmas typically operate in reactors with sizes of tens of centimetres, scaling up the pressure to atmospheric pressure the size of the plasma reduces to typical sizes below 1 mm. A natural approach of stabilizing atmospheric pressure plasmas is thus the use of microelectrode geometries. Traditionally microplasmas have been produced in confined geometries which allow one to stabilize dc excited discharges. This stabilization is intrinsically connected to the large surface-to-volume ratio which enhances heat transfer and losses of charged and excited species to the walls. Currently challenging boundaries are pushed by producing microcavity geometries with dimensions of the order of 1 µm [8]. The subject of this special issue, diagnostics of microplasmas, is motivated by the many challenges in microplasma diagnostics in view of the complex chemistry and strong spatial (and even temporal) gradients of species densities and plasma properties. Atmospheric pressure plasmas have a very long history dating back more than 100 years, with early work of

Current status and prospects of the toxicological assessment of engineered nanomaterials

International Nuclear Information System (INIS)

Pacchiarotti, Francesca; Grollino, Maria Giuseppa; Leter, Giorgio

2015-01-01

Nano toxicology is a branch of experimental toxicology dealing with identification and characterization of the harmful biological effects of engineered nanomaterials. The physico-chemical properties of these materials affect their biological level interactions. From the first generation of experimental studies it showed the need for adaptation to nanomaterials methodologies and toxicological evaluation of current strategies. Special challenges are presented by the variety of materials to be tested, from the definition of relevant dose quantities, by the standardization of the preparation and characterization of the nanomaterial in the biological sample matrices, by techniques for the determination of the biodistribution in the body. 'Omics' technologies are now an innovative tool for toxicological approach based on understanding the mechanisms of action, which will allow the most advanced laboratories to implement high-performance screening test. [it

Special Issue: Selected Articles from the 1996 NORCHIP Seminar

DEFF Research Database (Denmark)

1998-01-01

This Special Issue of Analog Integrated Circuits and Signal Processing presents extended versions of selected papers from the 14th NORCHIP Conference which was held November 4-5, in Helsinki, Finland...

Lidar Remote Sensing for Characterizing Forest Vegetation - Special Issue. Foreword

Science.gov (United States)

Popescu, Sorin C.; Nelson, Ross F.

2011-01-01

The Silvilaser 2009 conference held in College Station, Texas, USA, was the ninth conference in the Silvilaser series, which started in 2002 with the international workshop on using lidar (Light Detection and Ranging) for analyzing forest structure, held in Victoria, British Columbia, Canada. Following the Canadian workshop, subsequent forestry-lidar conferences took place in Australia, Sweden, Germany, USA, Japan, Finland, and the United Kingdom (UK). By the time this Silvilaser 2009 special issue of PE&RS is published, the 10th international conference will have been held in Freiburg, Germany, and planning will be ongoing for the 11th meeting to take place in Tasmania, Australia, in October 2011. Papers presented at the 2005 conference held in Blacksburg, Virginia, USA, were assembled in a special issue of PE&RS published in December 2006. Other special issues resulting from previous conferences were published in journals such as the Canadian Journal of Remote Sensing (2003), the Scandinavian Journal of Forest Research (2004), and Japan s Journal of Forest Planning (2008). Given the conference history and the much longer record of publications on lidar applications for estimating forest biophysical parameters, which dates back to the early 1980s, we may consider lidar an established remote sensing technology for characterizing forest canopy structure and estimating forest biophysical parameters. Randy Wynne, a professor at Virginia Tech and the final keynote speaker at Silvilaser 2009, made the case that it was time to push 30 years of research into operations, along the lines of what has already been done to good effect in the Scandinavian countries. In Randy s words, it s time to "Just do it!" This special issue includes a selection of papers presented during the 2009 Silvilaser conference, which consisted of eight sections as follows: (1) biomass and carbon stock estimates, (2) tree species and forest type classification, (3) data fusion and integration, (4, 5

DSH: Special Issue 'Digital Humanities 2014'

OpenAIRE

Terras Melissa; Clivaz Claire; Verhoeven Deb; Kaplan Frédéric

2015-01-01

The special issue presents selected proceedings from Digital Humanities 2014. Digital Humanities is the annual conference organized and sponsored by the Alliance of Digital Humanities Organizations (ADHO) and between 7th and 12th July 2014 over 700 attendees gathered for DH2014 at the University of Lausanne and the École polytechnique fédérale de Lausanne Switzerland (http://dh2014.org/): to date this remains the largest ever meeting of Digital Humanities scholars worldwide. Traditionally the...

[Preface for genome editing special issue].

Science.gov (United States)

Gu, Feng; Gao, Caixia

2017-10-25

Genome editing technology, as an innovative biotechnology, has been widely used for editing the genome from model organisms, animals, plants and microbes. CRISPR/Cas9-based genome editing technology shows its great value and potential in the dissection of functional genomics, improved breeding and genetic disease treatment. In the present special issue, the principle and application of genome editing techniques has been summarized. The advantages and disadvantages of the current genome editing technology and future prospects would also be highlighted.

Special Issue: Selected Articles from the 1994 NORCHIP Seminar

DEFF Research Database (Denmark)

1996-01-01

This Special Issue of Analog Integrated Circuits and Signal Processing presents extended versions of selected papers from the 12th NORCHIP Seminar which was held November 8-9, 1994, in Gothenburg, Sweden....

Toxicology in the use, misuse and abuse of food, drugs and chemicals

Energy Technology Data Exchange (ETDEWEB)

Chambers, P.L.; Chambers, C.M.; Gitter, S.

1983-01-01

The present proceedings containing 77 papers were presented at a meeting of the European Society of Toxicology held in Tel Aviv, March 21-24, 1982. The topics were: Effects of foreign substances on blood, drugs of abuse with special reference to marijuana and phencyclidine, toxic agents in food, xenobiotics, novel and new techniques in toxicology and miscellaneous toxic effects. Individual abstracts are prepared of 11 papers.

Results of a Wildlife Toxicology Workshop held by the Smithsonian Institution ? Identification and prioritization of problem statements

Science.gov (United States)

Grim, K.C.; Fairbrother, A.; Monfort, S.; Tan, S.; Rattner, B.A.; Gerould, S.; Beasley, V.; Aguirre, A.; Rowles, T.

2007-01-01

On March 13-15, 2007 nearly 50 scientists and administrators from the US and Canada participated in a Smithsonian-sponsored Wildlife Toxicology Workshop. Invitees were from academic, government, conservation and the private organizations and were selected to represent the diverse disciplines that encompass wildlife toxicology. The workshop addressed scientific and policy issues, strengths and weaknesses of current research strategies, interdisciplinary and science-based approaches in the study of complex contaminant issues, mechanisms for disseminating data to policy-makers, and the development of a partner network to meet the challenges facing wildlife toxicology over the next decade. Prior to the meeting, participants were asked to submit issues they deemed to be of highest concern which shaped four thematic groups for discussion: Wildlife Toxicology in Education, Risk Assessment, Multiple Stressors/Complex Mixtures, and Sub-Lethal to Population-Level Effects. From these discussion groups, 18 problem statements were developed and prioritized outlining what were deemed the most important issues to address now and into the future. Along with each problem statement participants developed potential solutions and action steps geared to move each issue forward. The workshop served as a stepping stone for action in the field of wildlife toxicology. These problem statements and the resulting action items are presented to the inter-disciplinary wildlife toxicology community for adoption, and future work and action items in these areas are encouraged. The workshop outcome looks to generate conversation and collaboration that will lead to the development of innovative research, future mechanisms for funding, workshops, working groups, and listserves within the wildlife toxicology community.

Editorial safety science special issue road safety management.

NARCIS (Netherlands)

Wegman, F.C.M. & Hagezieker, M.P.

2014-01-01

The articles presented in this Special Issue on Road Safety Management represent an illustration of the growing interest in policy-related research in the area of road safety. The complex nature of this type of research combined with the observation that scientific journals pay limited attention to

Editorial : Special Issue on Advances in Computer Entertainment

NARCIS (Netherlands)

Romão, Teresa; Nijholt, Anton; Cheok, Adrian David

2015-01-01

This special issue of the International Journal of Arts and Technology comprises a selection of papers from ACE 2012, the 9th International Conference on Advances in Computer Entertainment (Nijholt et al., 2012). ACE is the leading scientific forum for the dissemination of cutting-edge research

Research Models in Developmental Behavioral Toxicology.

Science.gov (United States)

Dietrich, Kim N.; Pearson, Douglas T.

Developmental models currently used by child behavioral toxicologists and teratologists are inadequate to address current issues in these fields. Both child behavioral teratology and toxicology scientifically study the impact of exposure to toxic agents on behavior development: teratology focuses on prenatal exposure and postnatal behavior…

CALL FOR PAPERS: Special issue on the random search problem: trends and perspectives

Science.gov (United States)

da Luz, Marcos G. E.; Grosberg, Alexander Y.; Raposo, Ernesto P.; Viswanathan, Gandhi M.

2008-11-01

This is a call for contributions to a special issue of Journal of Physics A: Mathematical and Theoretical dedicated to the subject of the random search problem. The motivation behind this special issue is to summarize in a single comprehensive publication, the main aspects (past and present), latest developments, different viewpoints and the directions being followed in this multidisciplinary field. We hope that such a special issue could become a particularly valuable reference for the broad scientific community working with the general random search problem. The Editorial Board has invited Marcos G E da Luz, Alexander Y Grosberg, Ernesto P Raposo and Gandhi M Viswanathan to serve as Guest Editors for the special issue. The general question of how to optimize the search for specific target objects in either continuous or discrete environments when the information available is limited is of significant importance in a broad range of fields. Representative examples include ecology (animal foraging, dispersion of populations), geology (oil recovery from mature reservoirs), information theory (automated researchers of registers in high-capacity database), molecular biology (proteins searching for their sites, e.g., on DNA ), etc. One reason underlying the richness of the random search problem relates to the `ignorance' of the locations of the randomly located `targets'. A statistical approach to the search problem can deal adequately with incomplete information and so stochastic strategies become advantageous. The general problem of how to search efficiently for randomly located target sites can thus be quantitatively described using the concepts and methods of statistical physics and stochastic processes. Scope Thus far, to the best of our knowledge, no recent textbook or review article in a physics journal has appeared on this topic. This makes a special issue with review and research articles attractive to those interested in acquiring a general introduction to the

Power and environmental assessment: Introduction to the special issue

International Nuclear Information System (INIS)

Cashmore, Matthew; Richardson, Tim

2013-01-01

The significance of politics and power dynamics has long been recognised in environmental assessment (EA) research, but there has not been sustained attention to power, either theoretically or empirically. The aim of this special issue is to encourage the EA community to engage more consistently with the issue of power. The introduction represents a ground-clearing exercise intended to clarify the terms of the debate about power in the EA field, and to contribute to the development of a research agenda. Research trends in the field are outlined, and potential analytic and normative lines of inquiry are identified. The contributions to this special issue represent contrasting conceptual and methodological approaches that navigate the analytical and normative terrain of power dynamics in EA. Together, they demonstrate that power cannot be removed from EA policy or practices, and is a necessary research focus for the development of the field. - Highlights: ► Introduces the themed section on power ► Provides an overview of the papers in the themed section ► Identifies research trends and directions for future research

Special issue - Applying the accelerator

International Nuclear Information System (INIS)

Anon.

1995-01-01

T'he CERN Courier is the international journal of high energy physics, covering current developments in and around this branch of basic science. A recurrent theme is applying the technology developed for particle accelerators, the machines which produce beams of high energy particles for physics experiments. Twentieth-century science is full of similar examples of applications derived from pure research. This special issue of the CERN Courier is given over to one theme - the applications of accelerators. Accelerator systems and facilities are normally associated with highenergy particle physics research, the search for fundamental particles and the quest to understand the physics of the Big Bang. To the layman, accelerator technology has become synonymous with large and expensive machines, exploiting the most modern technology for basic research. In reality, the range of accelerators and their applications is much broader. A vast number of accelerators, usually much smaller and operating for specific applications, create wealth and directly benefit the population, particularly in the important areas of healthcare, energy and the environment. There are well established applications in diagnostic and therapeutic medicine for research and routine clinical treatments. Accelerators and associated technologies are widely employed by industry for manufacturing and process control. In fundamental and applied research, accelerator systems are frequently used as tools. The biennial conference on the Applications of Accelerators in Industry and Research at Denton, Texas, attracts a thousand participants. This special issue of the CERN Courier includes articles on major applications, reflecting the diversity and value of accelerator technology. Under Guest Editor Dewi Lewis of Amersham International, contributions from leading international specialists with experience of the application end of the accelerator chain describe their fields of direct interest. The

Special issue - Applying the accelerator

Energy Technology Data Exchange (ETDEWEB)

Anon.

1995-07-15

T'he CERN Courier is the international journal of high energy physics, covering current developments in and around this branch of basic science. A recurrent theme is applying the technology developed for particle accelerators, the machines which produce beams of high energy particles for physics experiments. Twentieth-century science is full of similar examples of applications derived from pure research. This special issue of the CERN Courier is given over to one theme - the applications of accelerators. Accelerator systems and facilities are normally associated with highenergy particle physics research, the search for fundamental particles and the quest to understand the physics of the Big Bang. To the layman, accelerator technology has become synonymous with large and expensive machines, exploiting the most modern technology for basic research. In reality, the range of accelerators and their applications is much broader. A vast number of accelerators, usually much smaller and operating for specific applications, create wealth and directly benefit the population, particularly in the important areas of healthcare, energy and the environment. There are well established applications in diagnostic and therapeutic medicine for research and routine clinical treatments. Accelerators and associated technologies are widely employed by industry for manufacturing and process control. In fundamental and applied research, accelerator systems are frequently used as tools. The biennial conference on the Applications of Accelerators in Industry and Research at Denton, Texas, attracts a thousand participants. This special issue of the CERN Courier includes articles on major applications, reflecting the diversity and value of accelerator technology. Under Guest Editor Dewi Lewis of Amersham International, contributions from leading international specialists with experience of the application end of the accelerator chain describe their fields of direct interest. The contributions

Toxicología clínica comunitaria Community Clinical Toxicology

Directory of Open Access Journals (Sweden)

María Elena Leal

2011-08-01

Full Text Available En algunos países de América Latina las intoxicaciones agudas se manejan de manera profesional por médicos especialistas en la mate-ria. Algo similar ocurre con las intoxicaciones crónicas de origen laboral en el sector formal. No obstante, una realidad diferente ocurre en cuanto a la evaluación de las intoxicaciones crónicas de origen ambiental, dado que éstas por su naturaleza, son más difíciles de diagnosticar. Para el tratamiento de las intoxicaciones agudas se han organizado Centros de Información y Atención Toxicológica, pero para las intoxicaciones crónicas ambientales no se ha generado organismos semejantes. Por consiguiente, en este trabajo sugerimos un modelo de atención de la intoxicaciones crónicas a través de grupos multidisciplinarios bajo el esquema de una nueva disciplina: la Toxicología Clínica Comunitaria, cuyo objetivo sería la atención simultánea de las intoxicaciones agudas que generalmente se atienden en un ámbito hospitalario y de las intoxicaciones ambientales que por lo normal se presentan a nivel comunitario. El objetivo final es aprovechar la experiencia que existe en la Región en cuanto a Toxicología Clínica para organizar el trabajo comunitario.In some Latin American countries acute intoxication is professionally managed by specialized physicians qualified in the area. Something similar occurs with work-related chronic intoxication in the formal sector. However, a different reality prevails for the assessment of chronic intoxication of environmental origin, since it is by definition more difficult to diagnose. For treatment of acute intoxication, Toxicological Information and Care Centers have been set up, though similar bodies have not been created for chronic environmental intoxication. Therefore, in this study a model of chronic intoxication care is proposed, using multidisciplinary teams adopting a new approach, namely Community Clinical Toxicology, the goal of which would be the

Toxicology elements

International Nuclear Information System (INIS)

Viala, A.

1998-01-01

This work studies the different aspects of the modern toxicology: toxico-kinetic, biological, medico legal, food, professional, pharmaceuticals, environmental, social and regulatory. It is divided in three parts that consider the principle problems of general toxicology and analytical toxicology. (N.C.)

Preface JFDE Special Issue Glass

Directory of Open Access Journals (Sweden)

Ulrich Knaack

2015-05-01

Full Text Available Facade Design and Engineering is a multidisciplinary field that touches many other scientific disciplines. Glass is one of the key materials for building envelopes, and a strong scientific community has developed over the last decade. Designers love glass for its transparency. It is strong but brittle and very demanding in terms of engineering. We continuously see new innovative developments in terms of its climatic performance, structural possibilities, construction design and new applications. Reason enough to dedicate this special issue to the topic. The issue would not have been possible without the contribution of our special editors Jan Belis and Christian Louter, who contributed through their outstanding editorial work and network. Most of the papers in this issue were carefully selected from of a number of invited submissions and conference papers of the COST Action TU0905 Mid-Term Conference, April 17+18 2013, Porec, (CRC Press/Balkema, Leiden and subsequently subjected to the regular blind review process of the journal. Glass as a building material demonstrates the nature of the architectural discipline, where science and building practice are closely linked. Buildings are the live testing bed for scientific research and, at the same time, building practice formulates new research questions. We found that many articles sent to us deal with this relation. Therefore we decided to introduce the new category ’Applied Practice’ for certain journal paper contributions, which from now on can be found at the end of each issue. Although they do not need to be purely scientific, ’Applied Practice’ papers will always discuss new developments, will have a clear structure and are subjected to the strict JFDE review process. Façade Design and Engineering is a peer reviewed, open access journal, funded by The Netherlands Organisation for Scientific Research NWO (www.nwo.nl. We see ’open access’ as the future publishing model. But it

Green toxicology.

Science.gov (United States)

Maertens, Alexandra; Anastas, Nicholas; Spencer, Pamela J; Stephens, Martin; Goldberg, Alan; Hartung, Thomas

2014-01-01

Historically, early identification and characterization of adverse effects of industrial chemicals was difficult because conventional toxicological test methods did not meet R&D needs for rapid, relatively inexpensive methods amenable to small amounts of test material. The pharmaceutical industry now front-loads toxicity testing, using in silico, in vitro, and less demanding animal tests at earlier stages of product development to identify and anticipate undesirable toxicological effects and optimize product development. The Green Chemistry movement embraces similar ideas for development of less toxic products, safer processes, and less waste and exposure. Further, the concept of benign design suggests ways to consider possible toxicities before the actual synthesis and to apply some structure/activity rules (SAR) and in silico methods. This requires not only scientific development but also a change in corporate culture in which synthetic chemists work with toxicologists. An emerging discipline called Green Toxicology (Anastas, 2012) provides a framework for integrating the principles of toxicology into the enterprise of designing safer chemicals, thereby minimizing potential toxicity as early in production as possible. Green Toxicology`s novel utility lies in driving innovation by moving safety considerations to the earliest stage in a chemical`s lifecycle, i.e., to molecular design. In principle, this field is no different than other subdisciplines of toxicology that endeavor to focus on a specific area - for example, clinical, environmental or forensic toxicology. We use the same principles and tools to evaluate an existing substance or to design a new one. The unique emphasis is in using 21st century toxicology tools as a preventative strategy to "design out" undesired human health and environmental effects, thereby increasing the likelihood of launching a successful, sustainable product. Starting with the formation of a steering group and a series of workshops

Special Issue on advanced and emerging light sources

NARCIS (Netherlands)

Haverlag, M.; Kroesen, G.M.W.; Ferguson, I.

2011-01-01

EDITORIAL The papers in this special issue of Journal of Physics D: Applied Physics (JPhysD) originate from the 12th International Symposium on the Science and Technology of Light Sources and the 3rd International Conference on White LEDs and Solid State Lighting, held 11–16 July 2010 at Eindhoven

Special journal issue focuses on urban violence, poverty, and ...

International Development Research Centre (IDRC) Digital Library (Canada)

2015-10-02

Oct 2, 2015 ... In a special issue of the journal, Mouvements et enjeux sociaux [Social ... what works and what doesn't — to reduce violence in urban centres. ... to prevent crime, including mental health support, building community trust.

An Introduction to the Special Issue. Politics of Precarity

DEFF Research Database (Denmark)

Schierup, Carl-Ulrik; Bak Jørgensen, Martin

2016-01-01

The current special issue examines the range and strength of analysing contemporary transformations and struggles through the lens of ‘precarity’. Rather than defining a single precariat, the interest is in exploring ‘varieties of precarity’. These take different forms in different parts of the w......The current special issue examines the range and strength of analysing contemporary transformations and struggles through the lens of ‘precarity’. Rather than defining a single precariat, the interest is in exploring ‘varieties of precarity’. These take different forms in different parts...... of the world, on different scales and in different socio-economic contexts, and yet they share certain characteristics in terms of conditions and capacity for agency. Contributions to this volume testify that precarity may be a political proposition as much as a sociological category that offers an analytical...

Cornerstones of Toxicology.

Science.gov (United States)

Hayes, A Wallace; Dixon, Darlene

2017-01-01

The 35th Annual Society of Toxicologic Pathology Symposium, held in June 2016 in San Diego, California, focused on "The Basis and Relevance of Variation in Toxicologic Responses." In order to review the basic tenants of toxicology, a "broad brush" interactive talk that gave an overview of the Cornerstones of Toxicology was presented. The presentation focused on the historical milestones and perspectives of toxicology and through many scientific graphs, data, and real-life examples covered the three basic principles of toxicology that can be summarized, as dose matters (as does timing), people differ, and things change (related to metabolism and biotransformation).

Special issue of Higher-Order and Symbolic Computation

DEFF Research Database (Denmark)

Danvy, Olivier; Sabry, Amr

This issue of HOSC is dedicated to the general topic of continuations. It grew out of the third ACM SIGPLAN Workshop on Continuations (CW'01), which took place in London, UK on January 16, 2001 [3]. The notion of continuation is ubiquitous in many different areas of computer science, including...... and streamline Filinski's earlier work in the previous special issue of HOSC (then LISP and Symbolic Computation) that grew out of the first ACM SIGPLAN Workshop on Continuations [1, 2]. Hasegawa and Kakutani's article is the journal version of an article presented at FOSSACS 2001 and that received the EATCS...

Introduction to the Special Issue on Climate Ethics: Uncertainty, Values and Policy.

Science.gov (United States)

Roeser, Sabine

2017-10-01

Climate change is a pressing phenomenon with huge potential ethical, legal and social policy implications. Climate change gives rise to intricate moral and policy issues as it involves contested science, uncertainty and risk. In order to come to scientifically and morally justified, as well as feasible, policies, targeting climate change requires an interdisciplinary approach. This special issue will identify the main challenges that climate change poses from social, economic, methodological and ethical perspectives by focusing on the complex interrelations between uncertainty, values and policy in this context. This special issue brings together scholars from economics, social sciences and philosophy in order to address these challenges.

CALL FOR PAPERS: Special issue on Symmetries and Integrability of Difference Equations

Science.gov (United States)

Doliwa, Adam; Korhonen, Risto; Lafortune, Stephane

2006-10-01

This is a call for contributions to a special issue of Journal of Physics A: Mathematical and General entitled `Special issue on Symmetries and Integrability of Difference Equations' as featured at the SIDE VII meeting held during July 2006 in Melbourne (http://web.maths.unsw.edu.au/%7Eschief/side/side.html). Participants at that meeting, as well as other researchers working in the field of difference equations and discrete systems, are invited to submit a research paper to this issue. This meeting was the seventh of a series of biennial meetings devoted to the study of integrable difference equations and related topics. The notion of integrability was first introduced in the 19th century in the context of classical mechanics with the definition of Liouville integrability for Hamiltonian flows. Since then, several notions of integrability have been introduced for partial and ordinary differential equations. Closely related to integrability theory is the symmetry analysis of nonlinear evolution equations. Symmetry analysis takes advantage of the Lie group structure of a given equation to study its properties. Together, integrability theory and symmetry analysis provide the main method by which nonlinear evolution equations can be solved explicitly. Difference equations, just as differential equations, are important in numerous fields of science and have a wide variety of applications in such areas as: mathematical physics, computer visualization, numerical analysis, mathematical biology, economics, combinatorics, quantum field theory, etc. It is thus crucial to develop tools to study and solve difference equations. While the theory of symmetry and integrability for differential equations is now well-established, this is not yet the case for discrete equations. The situation has undergone impressive development in recent years and has affected a broad range of fields, including the theory of special functions, quantum integrable systems, numerical analysis, cellular

Special nuclear materials cutoff exercise: Issues and lessons learned. Volume 3

Energy Technology Data Exchange (ETDEWEB)

Libby, R.A.; Segal, J.E.; Stanbro, W.D.; Davis, C.

1995-08-01

This document is appendices D-J for the Special Nuclear Materials Cutoff Exercise: Issues and Lessons Learned. Included are discussions of the US IAEA Treaty, safeguard regulations for nuclear materials, issue sheets for the PUREX process, and the LANL follow up activity for reprocessing nuclear materials.

Special nuclear materials cutoff exercise: Issues and lessons learned. Volume 3

International Nuclear Information System (INIS)

Libby, R.A.; Segal, J.E.; Stanbro, W.D.; Davis, C.

1995-08-01

This document is appendices D-J for the Special Nuclear Materials Cutoff Exercise: Issues and Lessons Learned. Included are discussions of the US IAEA Treaty, safeguard regulations for nuclear materials, issue sheets for the PUREX process, and the LANL follow up activity for reprocessing nuclear materials

Preface (of the second special issue

Directory of Open Access Journals (Sweden)

Barna Iantovics

2011-01-01

Full Text Available

The primary aim of this special issue entitled Advances in Applied Sciences was to make some preparative steps by collecting state of the art research papers necessary in the beginning of the project entitled “Electronic Health Records for the Next Generation Medical Decision Support in Romanian and Bulgarian National Healthcare Systems” abbreviated as NextGenElectroMedSupport, a Bilateral Cooperation Research Project between Romania and Bulgaria having as directors from Bulgaria Prof. dr. Roumen Kountchev, Technical University of Sofia and from Romania Senior Lecturer dr. Barna Iantovics from Petru Maior University of Targu Mures. [...]

Introduction to Special Issue on Transience

DEFF Research Database (Denmark)

Lønsmann, Dorte; Haberland, Hartmut; Hazel, Spencer

2017-01-01

In this introduction to the special issue, the concept of transience is introduced as a theoretical perspective and as an object of research. The perspective of transience foregrounds the temporality of norm formation, located within the practices of people on the move. The introduction suggests......, as it is in the process of communities coming into being that norms emerge. Transience, in spite of being ubiquitous, is not always salient for members or analysts, but to identify, fixate and theorize it as an object of study in linguistic anthropology invites new ways of conceptualizing the interdependence of language...

Editorial: Special Issue on Algorithms for Sequence Analysis and Storage

Directory of Open Access Journals (Sweden)

Veli Mäkinen

2014-03-01

Full Text Available This special issue of Algorithms is dedicated to approaches to biological sequence analysis that have algorithmic novelty and potential for fundamental impact in methods used for genome research.

Technical Scientific Attaches and domotics. A special issue; Technisch Wetenschappelijk Attaches en domotica. Special

Energy Technology Data Exchange (ETDEWEB)

Kleinenberg, R.A. [Ministerie van Economische Zaken, The Hague (Netherlands); Uythof, B.H. [Invenit, Domotica Platform Nederland, Amsterdam (Netherlands); Benedetti, D [Ufficio Tecnico-Scientifico, Ambasciata del Regno dei Paesi Bassi, Rome (Italy); Van Wijngaarden, W.L. [Buero fuer Wissenschaft und Technologie, Kgl. Niederlaendische Botschaft, Bonn (Germany); Leniger, H.D.F. [Bureau du Conseiller Scientifique et Technique, Ambassade des Pays-Bas, Paris (France); Kieboom, J.P. [Office for Science and Technology, Royal Netherlands Embassy, Singapore (Singapore); Van Kooij, E.H. [Netherlands Office for Science and Technology, Royal Netherlands Embassy, Tokyo (Japan); Schuurmans, H.J.A. [Netherlands Office for Science and Technology, San Mateo, CA (United States)

2000-04-01

In this Dutch magazine Dutch businesses and institutes are informed about technological developments in industrialized countries (USA, Canada, Japan, South Korea, Taiwan, Singapore, Germany, France and Italy). In this special issue attaches in the different countries present information on developments and trends with respect to domotics, building automation, home networks, etc.

Special Issue: Book Reviews. Resources for Career Management, Counseling, Training and Development.

Science.gov (United States)

Horvath, Clara, Ed.; And Others

1995-01-01

This special issue includes reviews of 32 books on the following topics: management, human resources, and organizational development; career counseling, guidance, and assessment; job search; resumes; careers in specific fields; careers for special populations; career transitions; and finding balance. (SK)

Guest Editorial: Special issue: Selected papers from NorCAS 2016, the 2nd Nordic

DEFF Research Database (Denmark)

2017-01-01

complex digital systems to advanced analog and mixed-mode circuits. For this Special Issue, the papers are selected among those dealing with analog and mixed-mode circuits and systems. More than 25 papers were presented in this field, and from these, 8 papers have been selected for the Special Issue...

Editorial for special issue of AJIS on Green IT/IS (Sustainable computing

Directory of Open Access Journals (Sweden)

Michael Steven Lane

2011-03-01

Full Text Available We are pleased to present this AJIS Special issue on Green IT/IS (Sustainable Computing. There are five papers published in this special issue of the AJIS which reflect the diversity of this emerging and important area of research in Information Systems. Environmental sustainability is one of if not the most important challenge facing organisations and society in the 21st century. Information systems and information technology have a major role to play in both reducing its environmental impact and providing the systems and technological innovation to reduce the environmental impact of organisations. Currently there is a lack of rigorous empirical studies which are theory and evidence based to provide a sound basis for understanding IT green best practices and how these can be best adopted in organisations. This special issue of the AJIS contributes this current gap in the knowledge concerning green IS and IT with five empirical research papers which examined five different aspects of green IS and IT.

75 FR 21003 - National Toxicology Program (NTP); Office of Liaison, Policy and Review Meeting of the NTP Board...

Science.gov (United States)

2010-04-22

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Toxicology Program (NTP); Office of Liaison... toxicology study information from completed, ongoing, or anticipated studies, as well as information on... issues or topics in toxicology that could be appropriately addressed through studies on the nominated...

Some critical issues in special needs education as they relate to ...

African Journals Online (AJOL)

The study examines five critical issues in special education as they relate to visual impairment vis a vis mercy killing (euthanasia), gender, seclusion, castration and genetic engineering. Literature in the five stated issues was reviewed to provide an insight into these areas with particular reference to visual impairment.

Special Issue: 3D Printing for Biomedical Engineering.

Science.gov (United States)

Chua, Chee Kai; Yeong, Wai Yee; An, Jia

2017-02-28

Three-dimensional (3D) printing has a long history of applications in biomedical engineering. The development and expansion of traditional biomedical applications are being advanced and enriched by new printing technologies. New biomedical applications such as bioprinting are highly attractive and trendy. This Special Issue aims to provide readers with a glimpse of the recent profile of 3D printing in biomedical research.

Special Issue Dedication to Stephen H. Schneider

Directory of Open Access Journals (Sweden)

Paul Baer

2011-12-01

Full Text Available It is with both pleasure and sadness that we dedicate this special climate change issue of Portal to the late Dr. Stephen H. Schneider. Steve, as he was known to his friends and colleagues, was as rare a bird as any he sought out in his passion as a birdwatcher. A brilliant climate scientist, author of countless books and papers, path breaking inter-disciplinarian, eminent public communicator, mentor to dozens of young scholars; the list of roles and adulatory adjectives could fill an IPCC special report. Steve would have appreciated this special issue, with its multidisciplinary approach, and its quest for solutions based on analytical scholarship. He understood better than most the inseparability of normative and descriptive concerns, the need for academics and scientists of all kinds to be involved with public processes of communication, policy design and deliberation. While his last book was called “Science as a Contact Sport,” the unspoken title of his career might have been “Science as a Public Service.” He was endlessly testifying, consulting and giving interviews, and encouraged others to learn to do the same. Notwithstanding a battle with lymphoma in the last decade (chronicled in the wonderful book The Patient from Hell, Steve maintained a frenetic level of activity and was still going strong when he was felled by a pulmonary embolism in July of 2010 at age 65. He leaves behind a legacy embodied in his publications, institutions like the IPCC and the journal Climatic Change, and in the hearts and minds of the countless persons he interacted with, mentored, and loved. Exuberant, passionate, full of warmth and good humor, Steve was a mensch among mensches. He will be sorely missed. Paul Baer, with the assistance of Terry Root and Ian McGregor.

Islamic Education, Possibilities, Opportunities and Tensions: Introduction to the Special Issue

Science.gov (United States)

Waghid, Yusef; Davids, Nuraan

2014-01-01

If Islam continues to evoke skepticism, as it has done most intensely since 9/11, then it stands to reason that its tenets and education are viewed with equal mistrust, and as will be highlighted in this special issue, equal misunderstanding. The intention of this special edition is neither to counter the accusations Islam stands accused of, nor…

Inferentialism in mathematics education : introduction to a special issue

NARCIS (Netherlands)

Bakker, Arthur; Hußmann, Stephan

2017-01-01

Inferentialism, as developed by the philosopher Robert Brandom (1994, 2000), is a theory of meaning. The theory has wide-ranging implications in various fields but this special issue concentrates on the use and content of concepts. The key idea, relevant to mathematics education research, is that

Preface : Special Issue on Physical Movements and Playful Interaction

NARCIS (Netherlands)

Nijholt, Antinus; Nijholt, A.; Reidsma, D.; Reidsma, Dennis; Unknown, [Unknown

2010-01-01

This Special Issue of IJART is devoted to the 3rd International Conference on Intelligent Technologies for Interactive Entertainment (INTETAIN 09). This 3rd conference was held in Amsterdam, the Netherlands, in June 2009. It was organized by the Human Media Interaction (HMI) department of the

Foreword: Special issue devoted to the ESSDERC'07 conference

NARCIS (Netherlands)

Thewes, Roland; Schmitz, Jurriaan; Schmitz, J.

2008-01-01

This special issue of Solid-State Electronics is dedicated to topics discussed during the 37th European Solid-State Device Research Conference (ESSDERC) held in Munich in September 2007. It comprises seven plenary and invited papers written by eminent experts as well as 23 full-length contributed

Purchasing & supply management for a sustainable world: Introduction to the IPSERA 2013 conference special issue

DEFF Research Database (Denmark)

Johnsen, T. E.; Giannakis, M.; Miemczyk, J.

2014-01-01

Special issue of best papers of the 22nd annual IPSERA conference 2013: Purchasing & Supply Management for a Sustainable World......Special issue of best papers of the 22nd annual IPSERA conference 2013: Purchasing & Supply Management for a Sustainable World...

Psychosocial Studies of Migration and Community: Introduction to the Special Issue

OpenAIRE

Douglas D. Perkins; Neal A. Palmer; Manuel García-Ramírez

2011-01-01

Introducing the special issue on psychosocial studies of migration and community, we briefly reflect on the global increase in, and issues related to, both international and domestic migration, particularly from rural areas of less developed countries, which has fueled rapid urbanization and intercultural tensions in both post-industrial and developing countries. Topics covered in the issue are summarized, including an Italian study of the emotional impact of discrimination against immigrant ...

Special Issue on Gender and Writing | Gender and literacy issues and research: Placing the spotlight on writing

Directory of Open Access Journals (Sweden)

Judy M. Parr

2012-03-01

Full Text Available In this introduction to a special issue of the Journal of Writing Research, we review four decades of research, bringing writing to the forefront in conversations devoted to gender and literacy. We identify the impetus for much of the research on gender and writing and situate the four articles in this special issue within three themes: gender patterns in what and how students write, cognitive and socio-cultural factors influencing gender differences in student writing, and attempts to provide alternatives to stereotypical gender patterns in student writing. These interdisciplinary themes, further developed within the four articles, underscore the need to consider gender as a complex social, cognitive and linguistic characteristic of both reading and writing.

Green Toxicology – Application of predictive toxicology

DEFF Research Database (Denmark)

Vinggaard, Anne Marie; Wedebye, Eva Bay; Taxvig, Camilla

2014-01-01

safer chemicals and to identify problematic compounds already in use such as industrial compounds, drugs, pesticides and cosmetics, is required. Green toxicology is the application of predictive toxicology to the production of chemicals with the specific intent of improving their design for hazard...

Introduction to This Special Issue on Transnational HCI

DEFF Research Database (Denmark)

Shklovski, Irina; Vertesi, Janet; Lindtner, Silvia

2014-01-01

It is not surprising that HCI researchers are attracted to the role of technology in global processes as many of us already live inherently transnational lives. While the notion of global connectedness is hardly new, the issues that confront us are more than specific concerns for remote migration......, distributed work, or developing nations. Rather, we argue that transnational HCI is a contemporary condition of the design and use of technological systems, both at home and abroad. This special issue of Human-Computer Interaction is dedicated to exploring how and why a transnational lens matters to the study......, design, and development of computational systems. We consider this theoretical perspective in terms of both present technology use to construct and manage transnational relations and processes, and the possibilities such a lens opens for future research and design. The papers in this issue contribute...

Introduction to This Special Issue on Context-Aware Computing.

Science.gov (United States)

Moran, Thomas P.; Dourish, Paul

2001-01-01

Discusses pervasive, or ubiquitous, computing; explains the notion of context; and defines context-aware computing as the key to disperse and enmesh computation into our lives. Considers context awareness in human-computer interaction and describes the broad topic areas of the essays included in this special issue. (LRW)

Introduction to the Special Issue “Sport for Social Inclusion: Critical Analyses and Future Challenges”

Directory of Open Access Journals (Sweden)

Reinhard Haudenhuyse

2015-06-01

Full Text Available “Sport for Social Inclusion: Critical Analyses and Future Challenges” brings together a unique collection of papers on the subject of sport and social inclusion. The special issue can be divided into three major parts. The first part consists of three papers tacking on a broad perspective on sport and social exclusion, with specific attention to austerity policies, sport-for-change and exclusion in youth sports. The second part of the special issue tackles specific themes (e.g., group composition and dynamics, volunteering, physical education, youth work, equality, public health and groups (e.g., people with disabilities, disadvantaged girls, youth in society in relation to sport and social exclusion. The third part consists of three papers that are related to issues of multiculturalism, migration and social inclusion. The special issue is further augmented with a book review on Mike Collins and Tess Kay’s Sport and social exclusion (2nd edition and a short research communication. The editors dedicate the special issue to Mike Collins (deceased.

Special Issue: 3D Printing for Biomedical Engineering

Directory of Open Access Journals (Sweden)

Chee Kai Chua

2017-02-01

Full Text Available Three-dimensional (3D printing has a long history of applications in biomedical engineering. The development and expansion of traditional biomedical applications are being advanced and enriched by new printing technologies. New biomedical applications such as bioprinting are highly attractive and trendy. This Special Issue aims to provide readers with a glimpse of the recent profile of 3D printing in biomedical research.

SSDL Newsletter, No. 58 (Special Issue), June 2010

International Nuclear Information System (INIS)

2010-06-01

This is a Special Issue of the SSDL Newsletter. The original idea is to highlight the 40th anniversary of the IAEA/WHO TLD postal dose audit service. After forty years of operation, the service has verified the calibration of approximately 8000 radiotherapy beams in about 1700 hospitals worldwide. Several hundreds of dosimetry deviations have been identified and reconciled, thus avoiding potential dose misadministration to patients

Special Issue: Outcome of Anorexia Nervosa with Teenage Onset.

Science.gov (United States)

Casper, Regina C., Ed.

1996-01-01

The articles of this special issue report on studies of the outcomes of treatment of adolescent anorexia nervosa. These studies leave no doubt about the mortality risk and debilitating nature of chronic anorexia nervosa, but they do suggest that the prognosis, given expert treatment, is favorable for the most part. (SLD)

Toxicology of freshwater cyanobacteria.

Science.gov (United States)

Liyanage, H M; Arachchi, D N Magana; Abeysekara, T; Guneratne, L

2016-07-02

Many chemical contaminants in drinking water have been shown to cause adverse health effects in humans after prolonged exposure. Cyanobacteria are one of the most potent and diverse groups of photosynthetic prokaryotes. One key component of cyanobacterial success in the environment is the production of potent toxins as secondary metabolites, which have been responsible for numerous adverse health impacts in humans. Anthropogenic activities have led to the increase of eutrophication in freshwater bodies' worldwide, causing cyanobacterial blooms to become more frequent. The present article will discuss about harmful cyanobacteria and their toxicology with special references to microcystin, nodularin, and cylindrospermopsin.

Special issue of Higher-Order and Symbolic Computation

DEFF Research Database (Denmark)

solicited from papers presented at ASIAPEPM 02, the 2002 SIGPLAN Symposium on Partial Evaluation and Semantics-Based Program Manipulation [1]. The four articles were subjected to the usual process of journal reviewing. "Cost-Augmented Partial Evaluation of Functional Logic Programs" extends previous......The present issue is dedicated to Partial Evaluation and Semantics-Based Program Manipulation. Its first two articles were solicited from papers presented at PEPM 02, the 2002 ACMSIGPLANWorkshop on Partial Evaluation and Semantics-Based Program Manipulation [2], and its last two articles were...... narrowing-driven techniques of partial evaluation for functional-logic programs by the inclusion of abstract computation costs into the partial-evaluation process. A preliminary version of this work was presented at PEPM 02. "Specialization Scenarios: A Pragmatic Approach to Declaring Program Specialization...

Special issue call for papers from Business Systems Research Journal

OpenAIRE

Pejić Bach, Mirjana

2011-01-01

A special issue oft he Business Systems Research Journal with extended versions of selected papers from the 11th International Symposium on Operations Research in Slovenia (SOR’11) will be published under the journal ‘s publishing standards.

Introduction to special issue on the ecology of clonal plants

Czech Academy of Sciences Publication Activity Database

Gross, K. L.; Herben, T.; Klimešová, Jitka

2017-01-01

Roč. 52, 3-4 (2017), s. 265-267 ISSN 1211-9520 Institutional support: RVO:67985939 Keywords : Introduction to special issue * clonal plants * clonal meeting Subject RIV: EH - Ecology, Behaviour OBOR OECD: Ecology Impact factor: 1.017, year: 2016

Special issues as criterion for journal quality evaluation: Letter to editor

Directory of Open Access Journals (Sweden)

Dadkhah Mehdi

2015-01-01

Full Text Available Predatory publishers are defined as publishers who have financial goals. This definition was introduced for the first time by Jeffrey Beall (2012. In some predatory publishers, we can find some papers that are not related to journal's aim and scope. These journals create special issues in order to publish papers that are not related to journal's aim and scope. Thus, we are faced with a question of how the editor of these journals could evaluate these papers. In some trusted journals, editor invites guest editors for special issues, which are related to journal's aim and scope. On the other hand predatory publishers, publish papers without any external reviewers or guest editors. In addition, some journals that publish irrelevant papers in regular issues are also found. This problem can be seen especially in some biological or life science journals. It seems that these problems pose new challenge for the academic world.

1. Introduction to the special issue on “Gastronomy and Revolution”

Directory of Open Access Journals (Sweden)

Manuela Albertone

2016-04-01

Full Text Available This number of our Journal is again a special, thematic issue, that brings to our readers the results of the Call on “Gastronomy and Revolution”, that we announced in 2014, and of the 2015 Seminar that followed the Call. In these few pages, we would like to provide a brief introduction to the theme of the issue.

Support of Publication Costs, Atlantic Meridional Overturning Circulation Special Issue of Deep Sea Research II Journal

Energy Technology Data Exchange (ETDEWEB)

Amy Honchar

2012-11-12

The contribution of funds from DOE supported publication costs of a special issue of Deep Sea Research arising from presentations at the First U.S. Atlantic Meridional Overturning Circulation (AMOC) Meeting held 4-6 May, 2009 to review the US implementation plan and its coordination with other monitoring activities. The special issue includes a total of 16 papers, including publications from three DOE-supported investigators (ie Sevellec, F., and A.V. Fedorov; Hu et. al., and Wan et. al.,). The special issue addresses DOE interests in understanding and simulation/modeling of abrupt climate change.

INTRODUCTION TO THE SPECIAL ISSUE ON COMBAT SPORT

Directory of Open Access Journals (Sweden)

Andrew M. Lane

2006-07-01

Full Text Available Combat Sports Special Issue Editorial INTRODUCTION TO THE SPECIAL ISSUE ON COMBAT SPORT The World heavyweight professional boxing championship is arguable the biggest prize in sport. Why is this the case? It is not just the glamour that is appealing, but also the intriguing appeal of two combatants in a fixed environment. All combat sports share this similarity and in doing so, combat sports become appealing for spectators to watch, provide competitors with their ultimate challenge, and provide sport scientists and medics with a rich environment to apply their work. The role of research and theory driven interventions is key to the credibility of sport science and sports medicine. An intervention and/or treatment must be based on sound reason and the effects should be considered beforehand, both positive and negative. Equally, the nature of combat sport, where the aim is to strike, throw, or grapple with an opponent which can lead to injury, invariably raises questions on whether it is morally acceptable for these activities to be called a sport. Therefore, thorough investigation of the nature of medical issues is needed. The case for banning boxing in inextricably linked to the notion that the aim of the sport is to cause harm to the opponent; if harm was minimized and injury became less of an injury, the case for banning boxing would be weak. Quite clearly there are a plethora of arguments that point to a need for theory driven research in combat sport, and plugging this gap in the literature is an aim of this special issue of the Journal of Sports Science and Medicine. Possibly the most convincing argument for me to get involved in driving this issue stems from experiences in applied work with professional boxers (Hall and Lane, 2001; Lane and Hall, 2003, amateur boxers (Lane, 2002, kickboxers (Lane, et al., 1999 and tae-kwon-do athletes (Chapman et al., 1997 in which a raft of situations and issues were presented that required answers based

Special issue on electron cyclotron wave physics, technology, and applications - Part 2

International Nuclear Information System (INIS)

Uckan, Nermin A.

2008-01-01

This issue of Fusion Science and Technology (FS and T) contains a compendium of full-length, peer-reviewed papers on electron cyclotron (EC) wave physics, technology, and applications on magnetically confined plasmas. The interest in this special issue started with a simple question from a single individual who asked if he could submit for publication in FS and T his paper ''ITER ECH Front Steering Upper Launcher,'' parts of which he was planning to present at the 14th Joint Workshop on Electron Cyclotron Emission and Electron Cyclotron Resonance Heating, Santorini Island, Greece, May 2006. Such interest quickly grew, and the decision was made to offer the same opportunity to other workshop participants as well as to other interested researchers from around the world to contribute to a special FS and T issue on EC wave physics, technology, and applications. The person who started this ''wave'' of interest is no other than Dr. Mark Henderson, who was later drafted and kindly agreed to serve as the guest editor for this issue. The worldwide research program on EC wave physics, technology, and applications has shown impressive progress over the past couple of years, and much of this progress is reflected in the fifty or so papers that are included in this two-part special issue - part 1 in August 2007 and part 2 in January 2008. To complement the contributed papers, several informative reviews, which will be valuable for years to come, were also invited and are included. These review papers provide an objective summary of the current state of the art in EC emission research, theory of EC waves, EC heating and current drive experiments, gyrotron development, launcher development, and transmission systems. In preparation for ITER, this special issue is timely and should be of interest to those already working in the field and to the new generation of scientists and engineers who will be the ones to design, build, and carry out experiments on ITER. We extend our

Toxicology screen

Science.gov (United States)

... this page: //medlineplus.gov/ency/article/003578.htm Toxicology screen To use the sharing features on this page, please enable JavaScript. A toxicology screen refers to various tests that determine the ...

Introduction to the Special Issue on “Optomechatronics”

Directory of Open Access Journals (Sweden)

Alexander W. Koch

2014-03-01

Full Text Available The field of optomechatronics combines the synergistic effects of optics, mechanics and electronics for efficient sensor development. Optical sensors for the measurement of mechanical quantities, equipped with appropriate electronic signal (preprocessing have a wide range of applications, from surface testing, stress monitoring, and thin film analysis to biochemical sensing. The aim of this special issue is to provide an overview of current research and innovative applications of optomechatronics in sensors.

BRAIN JOURNAL - PREFACE (OF THE FIRST SPECIAL ISSUE)

OpenAIRE

Bogdan Patrut

2010-01-01

BRAIN. Broad Research in Artificial Intelligence and Neuroscience, ISSN 2067-3957, Volume 1, July 2010, Special Issue on Complexity in Sciences and Artificial Intelligence Editors • Barna Iantovics, Petru Maior University, Targu Mures, Romania • Dumitru Rădoiu, Petru Maior University, Targu Mures, Romania • Marius Măruşteri, Universiy of Medicine and Pharmacy, Targu Mures, Romania • Matthias Dehmer, Institute for Bioinformatics and Translational Research, The Health and Life Scien...

Opioids in the Frame of New Psychoactive Substances Network: A Complex Pharmacological and Toxicological Issue.

Science.gov (United States)

Ventura, Ludovic; Carvalho, Felix; Dinis-Oliveira, Ricardo Jorge

2018-01-01

New psychoactive substances (NPS), often referred to as "legal highs" or "designer drugs", are derivatives and analogues of existing psychoactive drugs that are introduced in the recreational market to circumvent existing legislation on drugs of abuse. This systematic review aims to gather the state of the art regarding chemical, molecular pharmacology and toxicological information of opioid class of NPS. Chemical, pharmacological, toxicological and clinical effects of opioid class of NPS were searched in books and in PubMed (U.S. National Library of Medicine) without a limiting period. Within this class, fentanyl analogues are among the most frequently abused and pose several clinical concerns and therefore will be thoroughly discussed. Other opioid sub-categories of NPS frequently misused include AH-7921, MT-45, U-47700, U-50488, desomorphine, mitragynine, tramadol, tapentadol, salvinorin A and its analogue herkinorin. Due to inefficient monitoring techniques, as well as limited knowledge regarding the acute and long-term effects of opioids NPS, further clinical and forensic toxicological studies are required. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Toxicology ontology perspectives.

Science.gov (United States)

Hardy, Barry; Apic, Gordana; Carthew, Philip; Clark, Dominic; Cook, David; Dix, Ian; Escher, Sylvia; Hastings, Janna; Heard, David J; Jeliazkova, Nina; Judson, Philip; Matis-Mitchell, Sherri; Mitic, Dragana; Myatt, Glenn; Shah, Imran; Spjuth, Ola; Tcheremenskaia, Olga; Toldo, Luca; Watson, David; White, Andrew; Yang, Chihae

2012-01-01

The field of predictive toxicology requires the development of open, public, computable, standardized toxicology vocabularies and ontologies to support the applications required by in silico, in vitro, and in vivo toxicology methods and related analysis and reporting activities. In this article we review ontology developments based on a set of perspectives showing how ontologies are being used in predictive toxicology initiatives and applications. Perspectives on resources and initiatives reviewed include OpenTox, eTOX, Pistoia Alliance, ToxWiz, Virtual Liver, EU-ADR, BEL, ToxML, and Bioclipse. We also review existing ontology developments in neighboring fields that can contribute to establishing an ontological framework for predictive toxicology. A significant set of resources is already available to provide a foundation for an ontological framework for 21st century mechanistic-based toxicology research. Ontologies such as ToxWiz provide a basis for application to toxicology investigations, whereas other ontologies under development in the biological, chemical, and biomedical communities could be incorporated in an extended future framework. OpenTox has provided a semantic web framework for the implementation of such ontologies into software applications and linked data resources. Bioclipse developers have shown the benefit of interoperability obtained through ontology by being able to link their workbench application with remote OpenTox web services. Although these developments are promising, an increased international coordination of efforts is greatly needed to develop a more unified, standardized, and open toxicology ontology framework.

Taking Development Seriously: Critique of the 2008 "JME" Special Issue on Moral Functioning

Science.gov (United States)

Gibbs, John C.; Moshman, David; Berkowitz, Marvin W.; Basinger, Karen S.; Grime, Rebecca L.

2009-01-01

This essay comments on articles comprising a "Journal of Moral Education" Special Issue (September, 2008, 37[3]). The issue was intended to honour the 50th anniversary of Lawrence Kohlberg's doctoral dissertation and his subsequent impact on the field of moral development and education. The articles were characterised by the Issue editor (Don…

Distance learning in toxicology: Australia's RMIT program

International Nuclear Information System (INIS)

Ahokas, Jorma; Donohue, Diana; Rix, Colin; Wright, Paul

2005-01-01

RMIT University was the first to offer a comprehensive Masters of Toxicology in Australasia 19 years ago. In 2001 the program was transformed into two stages, leading to a Graduate Diploma and Master of Applied Science in Toxicology. Now, these programs are fully online and suitable for graduates living and working anywhere in the world. The modular distance-learning courses are specifically designed to equip students with essential skills for entering fields such as chemical and drug evaluation; risk assessment of chemicals in the workplace; environmental and food toxicology. RMIT's online course delivery system has made it possible to deliver the toxicology programs, both nationally and internationally. The learning material and interactive activities (tests and quizzes, discussion boards, chat sessions) use Blackboard and WebBoard, each with a different educational function. Students log in to a Learning Hub to access their courses. The Learning Hub enables students to extend their learning beyond the classroom to the home, workplace, library and any other location with Internet access. The teaching staff log in to the Learning Hub to maintain and administer the online programs and courses which they have developed and/or which they teach. The Learning Hub is also a communication tool for students and staff, providing access to email, a diary and announcements. The early experience of delivering a full toxicology program online is very positive. However this mode of teaching continues to present many interesting technical, educational and cultural challenges, including: the design and presentation of the material; copyright issues; internationalisation of content; interactive participation; and the assessment procedures

Guest editorial preface : Special Issue on Advances in Computer Entertainment

NARCIS (Netherlands)

Nijholt, Anton; Romão, Teresa; Cheok, Adrian D.

2013-01-01

This special issue of the International Journal of Creative Interfaces and Computer Graphics contains a selection of papers from ACE 2012, the 9th International Conference on Advances in Computer Entertainment (Nijholt et al., 2012). ACE is the leading scientific forum for dissemination of

Conceptual Metaphor and Embodied Cognition in Science Learning: Introduction to Special Issue

Science.gov (United States)

Amin, Tamer G.; Jeppsson, Fredrik; Haglund, Jesper

2015-01-01

This special issue of "International Journal of Science Education" is based on the theme "Conceptual Metaphor and Embodied Cognition in Science Learning." The idea for this issue grew out of a symposium organized on this topic at the conference of the European Science Education Research Association (ESERA) in September 2013.…

"Seeing is believing": perspectives of applying imaging technology in discovery toxicology.

Science.gov (United States)

Xu, Jinghai James; Dunn, Margaret Condon; Smith, Arthur Russell

2009-11-01

Efficiency and accuracy in addressing drug safety issues proactively are critical in minimizing late-stage drug attritions. Discovery toxicology has become a specialty subdivision of toxicology seeking to effectively provide early predictions and safety assessment in the drug discovery process. Among the many technologies utilized to select safer compounds for further development, in vitro imaging technology is one of the best characterized and validated to provide translatable biomarkers towards clinically-relevant outcomes of drug safety. By carefully applying imaging technologies in genetic, hepatic, and cardiac toxicology, and integrating them with the rest of the drug discovery processes, it was possible to demonstrate significant impact of imaging technology on drug research and development and substantial returns on investment.

Evidence-Based Toxicology.

Science.gov (United States)

Hoffmann, Sebastian; Hartung, Thomas; Stephens, Martin

Evidence-based toxicology (EBT) was introduced independently by two groups in 2005, in the context of toxicological risk assessment and causation as well as based on parallels between the evaluation of test methods in toxicology and evidence-based assessment of diagnostics tests in medicine. The role model of evidence-based medicine (EBM) motivated both proposals and guided the evolution of EBT, whereas especially systematic reviews and evidence quality assessment attract considerable attention in toxicology.Regarding test assessment, in the search of solutions for various problems related to validation, such as the imperfectness of the reference standard or the challenge to comprehensively evaluate tests, the field of Diagnostic Test Assessment (DTA) was identified as a potential resource. DTA being an EBM discipline, test method assessment/validation therefore became one of the main drivers spurring the development of EBT.In the context of pathway-based toxicology, EBT approaches, given their objectivity, transparency and consistency, have been proposed to be used for carrying out a (retrospective) mechanistic validation.In summary, implementation of more evidence-based approaches may provide the tools necessary to adapt the assessment/validation of toxicological test methods and testing strategies to face the challenges of toxicology in the twenty first century.

EDITORIAL: Special Issue on advanced and emerging light sources Special Issue on advanced and emerging light sources

Science.gov (United States)

Haverlag, Marco; Kroesen, Gerrit; Ferguson, Ian

2011-06-01

The papers in this special issue of Journal of Physics D: Applied Physics (JPhysD) originate from the 12th International Symposium on the Science and Technology of Light Sources and the 3rd International Conference on White LEDs and Solid State Lighting, held 11-16 July 2010 at Eindhoven University. Abstracts of all papers presented at this combined conference were published in the Conference Proceedings LS-WLED 2010 by FAST-LS, edited by M Haverlag, G M W Kroesen and T Taguchi. Special issues of the previous three LS conferences have been well-cited and have proven to be an important source of information for the lighting community. The 2010 LS-Symposium was a combined conference with the White LED Conference in order to enhance the scope of this conference series towards new light source technologies such as LEDs and OLEDs, and this co-operation will be continued in the future. Given the faster technology development in these areas it was also decided to shorten the interval between conferences from three to two years. Well over 200 invited presentations, landmark presentations and poster contributions were presented at the 2010 LS-Symposium. The organizing committee have selected from these a number of outstanding contributions with a high technological content and invited the authors to submit a full paper in JPhysD. The criteria were that the work should not be a repetition of the work already published in the Proceedings, but should be new, complete, within the scope of JPhysD, and meeting the normal quality standards of this journal. After peer review a combined set of 18 papers is published in this JPhysD special issue. In addition, a number of lighting-application-orientated papers will be published in a special issue of Journal of Light & Visual Environment later in 2011. The papers in this special issue of JPhysD show that research in the science and technology of light sources still covers a broad set of subject areas which includes both 'classical

Forensic Toxicology: An Introduction.

Science.gov (United States)

Smith, Michael P; Bluth, Martin H

2016-12-01

This article presents an overview of forensic toxicology. The authors describe the three components that make up forensic toxicology: workplace drug testing, postmortem toxicology, and human performance toxicology. Also discussed are the specimens that are tested, the methods used, and how the results are interpreted in this particular discipline. Copyright © 2016 Elsevier Inc. All rights reserved.

Cutting Edge PBPK Models and Analyses: Providing the Basis for Future Modeling Efforts and Bridges to Emerging Toxicology Paradigms

Directory of Open Access Journals (Sweden)

Jane C. Caldwell

2012-01-01

Full Text Available Physiologically based Pharmacokinetic (PBPK models are used for predictions of internal or target dose from environmental and pharmacologic chemical exposures. Their use in human risk assessment is dependent on the nature of databases (animal or human used to develop and test them, and includes extrapolations across species, experimental paradigms, and determination of variability of response within human populations. Integration of state-of-the science PBPK modeling with emerging computational toxicology models is critical for extrapolation between in vitro exposures, in vivo physiologic exposure, whole organism responses, and long-term health outcomes. This special issue contains papers that can provide the basis for future modeling efforts and provide bridges to emerging toxicology paradigms. In this overview paper, we present an overview of the field and introduction for these papers that includes discussions of model development, best practices, risk-assessment applications of PBPK models, and limitations and bridges of modeling approaches for future applications. Specifically, issues addressed include: (a increased understanding of human variability of pharmacokinetics and pharmacodynamics in the population, (b exploration of mode of action hypotheses (MOA, (c application of biological modeling in the risk assessment of individual chemicals and chemical mixtures, and (d identification and discussion of uncertainties in the modeling process.

Effects of the euro changeover on consumer behaviour: Introduction to the special issue

DEFF Research Database (Denmark)

Gärling, Tommy; Thøgersen, John

2007-01-01

This paper introduces the special issue "Effects of the euro changeover on consumer behaviour" by briefly reviewing the contents of the included papers. The introduction follows the organization of the papers in three sections each focusing on a common set of issues. In the first section, research...... revealing the perceived and actual problems consumers face after the euro changeover is described. Research illuminating learning and adaptation to the euro changeover is the focus of the second section. A special problem is the misperception of inflation after the euro changeover. Research on this problem...

Special issue on advances in computer entertainment: editorial

OpenAIRE

Romão, T.; Romão, Teresa; Nijholt, Antinus; Cheok, J.D.; Cheok, Adrian David

2015-01-01

This special issue of the International Journal of Arts and Technology comprises a selection of papers from ACE 2012, the 9th International Conference on Advances in Computer Entertainment (Nijholt et al., 2012). ACE is the leading scientific forum for dissemination of cutting-edge research results in the area of entertainment computing. The main goal of ACE is to stimulate discussion in the development of new and compelling entertainment computing and interactive art concepts and application...

Introduction to a special issue on genotype by environment interaction

Science.gov (United States)

Expression of a phenotype is a function of the genotype, the environment, and the differential sensitivity of certain genotypes to different environments, also known as genotype by environment (G × E) interaction. This special issue of Crop Science includes a collection of manuscripts that reviews t...

Overview on the ‘Atmospheric Emissions from Volcanoes’ Special Issue

Directory of Open Access Journals (Sweden)

Shona Mackie

2015-02-01

Full Text Available The session ‘Atmospheric Emissions from Volcanoes’ formed part of the 2014 General Assembly of the Europe-an Geosciences Union (EGU, held in Vienna from 27 April to 2 May. This special issue presents some of the work that was discussed during the session. [...

History of the Journal of the American College of Toxicology.

Science.gov (United States)

Christian, Mildred S

2004-01-01

This companion article to the History of the American College of Toxicology also is written in celebration of the 25th Anniversary of the American College of Toxicology (ACT). It relates how the official journal of the College evolved from a privately owned publication, the Journal of Environmental Pathology and Toxicology (JEPT), into publications owned and managed by the College and its Board, for the first 17 years as the Journal of the American College of Toxicology (JACT) and currently as The International Journal of Toxicology (IJT). It relates how the first journal focused on toxicological studies, potential cancer causes and concerns associated with environmental contamination and chemical exposure safety issues. It tells how this journal was replaced by one more broadly based that addressed multiple industries and regulatory approaches, accepted previously unpublishable "no-effect" studies, so important in eliminating unwarranted animal use, and provided review articles, rather than only original research. It also described how the JACT evolved into an international journal finally recognized for its quality reviews and peer-reviewed research. Each of the three journals that represented the College is described, as well as interesting events associated with their development and publication, including the activities and contributions of the first four editors in chief, Drs. Myron A. Mehlman, Mildred S. Christian, Robert M. Diener and Harihara Mehendale.

Entrepreneurial activity and regional development: an introduction to this special issue

Directory of Open Access Journals (Sweden)

Maribel Guerrero

2013-01-01

Full Text Available The main objective of this special issue is to analyze the relationship between entrepreneurial intention and entrepreneurial activity and its impact on regional development. The last convulsive decade, with expansionary and recessionary economic cycles, offers a good opportunity to study how economic cycles affect the propensity of becoming an entrepreneur and, in turn, to observe how entrepreneurial activity contributes to change (improvement in the economy.Previous studies have analyzed the complicated endogenous relationship between entrepreneurship and economic growth, but these studies have examined the countries’ performance under a static view. This special issue focuses on analyzing complex entrepreneurial behavior from a sub-national perspective (examining several regions in the Spanish autonomous communities and a dynamic view (using data from several years, which adds rigor and valuable knowledge to this research field.

Introduction to the special issue 'unintended effects of international cooperation'.

Science.gov (United States)

Koch, Dirk-Jan; Schulpen, Lau

2018-06-01

The 'Evaluation and Program Planning' journal has contributed to the launch of an academic discussion of unintended effects of international cooperation, notably by publishing in 2016 articles by Bamberger, Tarsilla, & Hesse-Biber and by Jabeen. This special issue aims to take up the academic challenges as laid down by those authors, by providing among others a clear typology and applying it, by outlining various methodological options and testing them, and elaborating on suggestions on how to deal with the barriers that prevent unintended effects being taken into account. This special issue makes clear that it is possible to reduce the share of unforeseen effects of international cooperation. Turning the spotlight on unintended effects that can be anticipated, and aiming to make progress on uncovering those that are particularly difficult to detect and debunking those that are exaggerated is the task that lies ahead of us. Copyright © 2017 Elsevier Ltd. All rights reserved.

Introduction to the Special Issue on Clinical Neuropsychology of Movement Disorders.

Science.gov (United States)

Tröster, Alexander I

2017-11-01

The special issue on the clinical neuropsychology of movement disorders provides an overview for the non-subspecialist clinical neuropsychologist and other clinical neuroscientists of the neuropsychological features, assessment and treatment of Parkinson's disease and Lewy body dementias, atypical parkinsonian disorders (corticobasal syndrome, progressive supranuclear palsy, and multiple system atrophy), Huntington's disease, dystonia, and amyotrophic lateral sclerosis. Additionally, articles provide overviews of neuropsychological and ethical issues related to deep brain stimulation and a discussion of non-pharamcologic and non-invasive treatment of cognitive dysfunction in Parkinson's disease. A search of PubMed using neuropsycholog* and parkinson* as search terms indicates that the number of articles dealing with neuropsychology of parkinsonian disorders has more than doubled in each of the past three decades (1990-99:269 entries, 2000-09:575 entries, 2010-17:967 entries). This rapid growth of research makes a special issue on the topic very timely. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Editorial Special Issue on Fluid Mechanics and Fluid Power (FMFP ...

Indian Academy of Sciences (India)

This special issue of Sadhana contains selected papers from two conferences related to fluid mechanics held in India recently, Fluid Mechanics and Fluid Power conference at NIT, Hamirpur, and an International Union of Theoretical ... A simple, well thought out, flow visualization experiment or a computation can sometimes ...

Special Issue: Honey Bee Viruses

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Sebastian Gisder

2015-10-01

Full Text Available Pollination of flowering plants is an important ecosystem service provided by wild insect pollinators and managed honey bees. Hence, losses and declines of pollinating insect species threaten human food security and are of major concern not only for apiculture or agriculture but for human society in general. Honey bee colony losses and bumblebee declines have attracted intensive research interest over the last decade and although the problem is far from being solved we now know that viruses are among the key players of many of these bee losses and bumblebee declines. With this special issue on bee viruses we, therefore, aimed to collect high quality original papers reflecting the current state of bee virus research. To this end, we focused on newly discovered viruses (Lake Sinai viruses, bee macula-like virus, or a so far neglected virus species (Apis mellifera filamentous virus, and cutting edge technologies (mass spectrometry, RNAi approach applied in the field.

Special Issue: Honey Bee Viruses

Science.gov (United States)

Gisder, Sebastian; Genersch, Elke

2015-01-01

Pollination of flowering plants is an important ecosystem service provided by wild insect pollinators and managed honey bees. Hence, losses and declines of pollinating insect species threaten human food security and are of major concern not only for apiculture or agriculture but for human society in general. Honey bee colony losses and bumblebee declines have attracted intensive research interest over the last decade and although the problem is far from being solved we now know that viruses are among the key players of many of these bee losses and bumblebee declines. With this special issue on bee viruses we, therefore, aimed to collect high quality original papers reflecting the current state of bee virus research. To this end, we focused on newly discovered viruses (Lake Sinai viruses, bee macula-like virus), or a so far neglected virus species (Apis mellifera filamentous virus), and cutting edge technologies (mass spectrometry, RNAi approach) applied in the field. PMID:26702462

TOXNET: Toxicology Data Network

Science.gov (United States)

... to TOXNET Your resource for searching databases on toxicology, hazardous chemicals, environmental health, and toxic releases SEARCH ... over 3,000 chemicals (1991-1998) Environmental Health & Toxicology Resources on environmental health and toxicology Visit Site ...

2008 Special NSREC Issue of the IEEE Transactions on Nuclear Science Comments by the Editors

Science.gov (United States)

Schwank, Jim; Buchner, Steve; Marshall, Paul; Duzellier, Sophie; Brown, Dennis; Poivey, Christian; Pease, Ron

2008-12-01

The December 2008 special issue of the IEEE Transactions on Nuclear Science contains selected papers from the 45th annual IEEE International Nuclear and Space Radiation Effects Conference (NSREC) held in Tucson, Arizona, July 14 - 18, 2008. Over 115 papers presented at the 2008 NSREC were submitted for consideration for this year's special issue. Those papers that appear in this special issue were able to successfully complete the review process before the deadline for the December issue. A few additional papers may appear in subsequent issues of the TRANSACTIONS. This publication is the premier archival journal for research on space and nuclear radiation effects in materials, devices, circuits, and systems. This distinction is the direct result of the conscientious efforts of both the authors, who present and document their work, and the reviewers, who selflessly volunteer their time and talent to help review the manuscripts. Each paper in this journal has been reviewed by experts selected by the editors for their expertise and knowledge of the particular subject areas.

TOXNET and Beyond - Using the National Library of Medicine's Environmental Health and Toxicology Portal

International Nuclear Information System (INIS)

Templin-Branner, Wilma

2011-01-01

The purpose of this training is to familiarize participants with reliable online environmental health and toxicology information, from the National Library of Medicine and other reliable sources. Skills and knowledge acquired in this training class will enable participants to access, utilize, and refer others to environmental health and toxicology information. After completing this course, participants will be able to: (1) Identify quality, accurate, and authoritative online resources pertaining to environmental health, toxicology, and related medical information; (2) Demonstrate the ability to perform strategic search techniques to find relevant online information; and (3) Apply the skills and knowledge obtained in this class to their organization's health information needs. NLMs TOXNET (Toxicology Data Network) is a free, Web-based system of databases on toxicology, environmental health, hazardous chemicals, toxic releases, chemical nomenclatures, and specialty areas such as occupational health and consumer products. Types of information in the TOXNET databases include: (1) Specific chemicals, mixtures, and products; (2) Unknown chemicals; and (3) Special toxic effects of chemicals in humans and/or animals.

A New Urban Agenda: Introduction to the Special Issue on “Sustainable Urban Development”

Directory of Open Access Journals (Sweden)

Steffen Lehmann

2015-07-01

Full Text Available Since the start of the 21st century, humanity has been a predominantly urban species. This Special Issue is about the future of cities and how urbanization will develop when based on principles of sustainability. It explores the underlying dimensions of the transformation of existing cities and the design of low carbon green precincts and their urban systems. The view of the papers presented in this Special Issue is holistic and takes questions of social sustainability into account. This editorial highlights the contents and methodologies of 13 selected papers, while presenting diverse issues in strategies, concepts and policies for sustainable urban development.

Metabolomics in Toxicology and Preclinical Research

Science.gov (United States)

Ramirez, Tzutzuy; Daneshian, Mardas; Kamp, Hennicke; Bois, Frederic Y.; Clench, Malcolm R.; Coen, Muireann; Donley, Beth; Fischer, Steven M.; Ekman, Drew R.; Fabian, Eric; Guillou, Claude; Heuer, Joachim; Hogberg, Helena T.; Jungnickel, Harald; Keun, Hector C.; Krennrich, Gerhard; Krupp, Eckart; Luch, Andreas; Noor, Fozia; Peter, Erik; Riefke, Bjoern; Seymour, Mark; Skinner, Nigel; Smirnova, Lena; Verheij, Elwin; Wagner, Silvia; Hartung, Thomas; van Ravenzwaay, Bennard; Leist, Marcel

2013-01-01

Summary Metabolomics, the comprehensive analysis of metabolites in a biological system, provides detailed information about the biochemical/physiological status of a biological system, and about the changes caused by chemicals. Metabolomics analysis is used in many fields, ranging from the analysis of the physiological status of genetically modified organisms in safety science to the evaluation of human health conditions. In toxicology, metabolomics is the -omics discipline that is most closely related to classical knowledge of disturbed biochemical pathways. It allows rapid identification of the potential targets of a hazardous compound. It can give information on target organs and often can help to improve our understanding regarding the mode-of-action of a given compound. Such insights aid the discovery of biomarkers that either indicate pathophysiological conditions or help the monitoring of the efficacy of drug therapies. The first toxicological applications of metabolomics were for mechanistic research, but different ways to use the technology in a regulatory context are being explored. Ideally, further progress in that direction will position the metabolomics approach to address the challenges of toxicology of the 21st century. To address these issues, scientists from academia, industry, and regulatory bodies came together in a workshop to discuss the current status of applied metabolomics and its potential in the safety assessment of compounds. We report here on the conclusions of three working groups addressing questions regarding 1) metabolomics for in vitro studies 2) the appropriate use of metabolomics in systems toxicology, and 3) use of metabolomics in a regulatory context. PMID:23665807

Special issue on Modern Trends in Inorganic Chemistry (MTIC-XV ...

Indian Academy of Sciences (India)

This Special Issue is based on the contributions from the invited speakers of the. Fifteenth Symposium on Modern Trends in Inorganic Chemistry (MTIC-XV) held at the Indian Institute of Technology, Roorkee during 13–16, December 2013. The MTIC series of biennial symposia has been an important forum for the inorganic ...

Introduction to the special issue Hermann Weyl and the philosophy of the 'New Physics'

Science.gov (United States)

De Bianchi, Silvia; Catren, Gabriel

2018-02-01

This Special Issue Hermann Weyl and the Philosophy of the 'New Physics' has two main objectives: first, to shed fresh light on the relevance of Weyl's work for modern physics and, second, to evaluate the importance of Weyl's work and ideas for contemporary philosophy of physics. Regarding the first objective, this Special Issue emphasizes aspects of Weyl's work (e.g. his work on spinors in n dimensions) whose importance has recently been emerging in research fields across both mathematical and experimental physics, as well as in the history and philosophy of physics. Regarding the second objective, this Special Issue addresses the relevance of Weyl's ideas regarding important open problems in the philosophy of physics, such as the problem of characterizing scientific objectivity and the problem of providing a satisfactory interpretation of fundamental symmetries in gauge theories and quantum mechanics. In this Introduction, we sketch the state of the art in Weyl studies and we summarize the content of the contributions to the present volume.

Research Article Special Issue

African Journals Online (AJOL)

pc

2018-03-07

Mar 7, 2018 ... characterized by historically developed specialization, a special geographical location ... We are listed under Research Associations category. ... product, service or technology providing economic and/or public benefit, additional in ...... the region's competitiveness // International Business Management.

Perspectives on working memory: introduction to the special issue.

Science.gov (United States)

Logie, Robert H; Cowan, Nelson

2015-04-01

More than 40 years ago, Baddeley and Hitch (1974) published an article with a wealth of experimentation and theorization on working memory, the small amount of information held in mind and often used within cognitive processes such as language comprehension and production, reasoning, and problem solving. We honor this seminal accomplishment in the present special issue, and take this opportunity to provide an introduction to our perspectives on the origin of the theory of working memory, how it has affected our work, what may be coming in the near future, and how the research articles in the present issue contribute to several related themes within the clearly thriving field of working memory.

Special Issue: NextGen Materials for 3D Printing

Directory of Open Access Journals (Sweden)

Chee Kai Chua

2018-04-01

Full Text Available Only a handful of materials are well-established in three-dimensional (3D printing and well-accepted in industrial manufacturing applications. However, recent advances in 3D printable materials have shown potential for enabling numerous novel applications in the future. This special issue, consisting of 2 reviews and 10 research articles, intends to explore the possible materials that could define next-generation 3D printing.

Editorial. Special issue on strategies and self-regulation in self-access learning

Directory of Open Access Journals (Sweden)

Heath Rose

2012-12-01

Full Text Available Learner strategy and self-regulation theory have been in a state of flux in recent years, and this is an exciting time to share new ideas, conceptualizations and models of research in order to move the field forward. Therefore, the editor was eager to pursue a special issue where emerging voices in these fields could be heard, and these new ideas could be shared. The representation of strategic learning in recent conferences is indicative of a growing trend in the field to move towards a self-access and learner autonomy perspective. There is great potential to share knowledge between these fields. This special issue brings these fields, which have already been gravitating together, closer in a more concrete and published format.

CALL FOR PAPERS: Special Issue on “The Gender Dimension in Technology”

Directory of Open Access Journals (Sweden)

Alejandro Jimenez M.

2009-12-01

Full Text Available This Special Issue aims to present to the scientific, business and policy-making communities a concentrated and multi-faceted body of recent research, that has the potential to raise awareness on the increasing importance of gender in technology, broaden the current understanding of the dynamics and implications of the phenomenon, inspire new research projects in this and related areas, and disseminate good practice. Note: The authors of the papers included in this Special Issue will have the opportunity to present them at the International Conference Triple Helix 8 (Madrid, October 2010, which will include a track on Gender and Technology. Further details on this track will be available shortly on the conference website http://www.triplehelix8.org/information.html

Association of American Geographers, Remote Sensing Specialty Group Special Issue of Geocarto International

Science.gov (United States)

Allen, Thomas R. (Editor); Emerson, Charles W. (Editor); Quattrochi, Dale A. (Editor); Arnold, James E. (Technical Monitor)

2001-01-01

This special issue continues the precedence of the Association of American Geographers (AAG), Remote Sensing Specialty Group (RSSG) for publishing selected articles in Geocarto International as a by-product from the AAG annual meeting. As editors, we issued earlier this year, a solicitation for papers to be published in a special issue of Geocarto International that were presented in RSSG-sponsored sessions at the 2001 AAG annual meeting held in New York City on February 27-March 3. Although not an absolute requisite for publication, the vast majority of the papers in this special issue were presented at this year's AAG meeting in New York. Other articles in this issue that were not part of a paper or poster session at the 2001 AAG meeting are authored by RSSG members. Under the auspices of the RSSG, this special Geocarto International issue provides even more compelling evidence of the inextricable linkage between remote sensing and geography. The papers in this special issue fall into four general themes: 1) Urban Analysis and Techniques for Urban Analysis; 2) Land Use/Land Cover Analysis; 3) Fire Modeling Assessment; and 4) Techniques. The first four papers herein are concerned with the use of remote sensing for analysis of urban areas, and with use or development of techniques to better characterize urban areas using remote sensing data. As the lead paper in this grouping, Rashed et al., examine the usage of spectral mixture analysis (SMA) for analyzing satellite imagery of urban areas as opposed to more 'standard' methods of classification. Here SMA has been applied to IRS-1C satellite multispectral imagery to extract measures that better describe the 'anatomy' of the greater Cairo, Egypt region. Following this paper, Weng and Lo describe how Landsat TM data have been used to monitor land cover types and to estimate biomass parameters within an urban environment. The research reported in this paper applies an integrated GIS (Geographic Information System

Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project

International Nuclear Information System (INIS)

Lindon, John C.; Nicholson, Jeremy K.; Holmes, Elaine; Antti, Henrik; Bollard, Mary E.; Keun, Hector; Beckonert, Olaf; Ebbels, Timothy M.; Reily, Michael D.; Robertson, Donald; Stevens, Gregory J.; Luke, Peter; Breau, Alan P.; Cantor, Glenn H.; Bible, Roy H.; Niederhauser, Urs; Senn, Hans; Schlotterbeck, Goetz; Sidelmann, Ulla G.; Laursen, Steen M.; Tymiak, Adrienne; Car, Bruce D.; Lehman-McKeeman, Lois; Colet, Jean-Marie; Loukaci, Ali; Thomas, Craig

2003-01-01

The role that metabonomics has in the evaluation of xenobiotic toxicity studies is presented here together with a brief summary of published studies. To provide a comprehensive assessment of this approach, the Consortium for Metabonomic Toxicology (COMET) has been formed between six pharmaceutical companies and Imperial College of Science, Technology and Medicine (IC), London, UK. The objective of this group is to define methodologies and to apply metabonomic data generated using 1 H NMR spectroscopy of urine and blood serum for preclinical toxicological screening of candidate drugs. This is being achieved by generating databases of results for a wide range of model toxins which serve as the raw material for computer-based expert systems for toxicity prediction. The project progress on the generation of comprehensive metabonomic databases and multivariate statistical models for prediction of toxicity, initially for liver and kidney toxicity in the rat and mouse, is reported. Additionally, both the analytical and biological variation which might arise through the use of metabonomics has been evaluated. An evaluation of intersite NMR analytical reproducibility has revealed a high degree of robustness. Second, a detailed comparison has been made of the ability of the six companies to provide consistent urine and serum samples using a study of the toxicity of hydrazine at two doses in the male rat, this study showing a high degree of consistency between samples from the various companies in terms of spectral patterns and biochemical composition. Differences between samples from the various companies were small compared to the biochemical effects of the toxin. A metabonomic model has been constructed for urine from control rats, enabling identification of outlier samples and the metabolic reasons for the deviation. Building on this success, and with the completion of studies on approximately 80 model toxins, first expert systems for prediction of liver and kidney

Contributions to the Content Analysis of Gender Roles: An Introduction to a Special Issue.

Science.gov (United States)

Rudy, Rena M; Popova, Lucy; Linz, Daniel G

2011-02-01

This special issue on gender-related content analysis is the second of two parts (see Rudy et al. 2010b). The current special issue is more diverse than was the first in the number of countries that are represented and in the variety of media genres and content types that are included. The primary aim of this paper is to outline some of the contributions of the individual papers in this second special issue. Some of these advancements and innovations include (a) examining underresearched measures, countries, time spans, sexual orientations, and individual media programs; (b) addressing both international and intranational differences in gender-role portrayals; (c) comparing multiple content formats within the same media unit; (d) updating past findings to take into consideration the current media landscape; (e) employing established measures in novel ways and novel contexts; (f) uncovering limitations in established intercultural measures and media-effects theories; (g) suggesting variables that could predict additional differences in gender-role portrayals; (h) adopting virtually identical methods and measures across distinct content categories in order to facilitate comparisons; (i) conducting multiple tests of a given hypothesis; (j) examining, from multiple perspectives, the implications of racial differences in gender portrayals; and (k) examining the implications of underrepresentation of women and the perspectives that women hold. In addition to the original content-analytical research presented in this special issue, two reviews, one methodological and the other analytical, offer recommendations of procedures and perspectives to be implemented in future research.

Toxicología Vegetal

OpenAIRE

García Fernández, Antonio Juan

2010-01-01

Presentaciones de clase de los temas de Toxicología Vegetal de la licenciatura de Veterinaria de la Universidad de Murcia del curso 2011/12. Presentaciones de Toxicología Vegetal de la asignatura de Toxicología de la Licenciatura de Veterinaria del curso 2011/12

Introduction to the special issue on visual aesthetics

Directory of Open Access Journals (Sweden)

Marković Slobodan

2017-01-01

Full Text Available Visual aesthetics encompasses the studies of the relationship between vision and various aesthetic phenomena - from the beauty ratings of simple visual patterns to the appreciation of visual art, from the preference for natural objects and scenes to the preference for products of human creativity, from the aesthetic effects of culture to the aesthetic effects of biology, from the universal aesthetic sensitivity to the individual differences in taste, and so on. In this special issue ten papers reported the most recent studies on very different subjects related to visual aesthetics.

Metabonomics and toxicology.

Science.gov (United States)

Zhao, Liang; Hartung, Thomas

2015-01-01

Being an emerging field of "omics" research, metabonomics has been increasingly used in toxicological studies mostly because this technology has the ability to provide more detailed information to elucidate mechanism of toxicity. As an interdisciplinary field of science, metabonomics combines analytical chemistry, bioinformatics, statistics, and biochemistry. When applied to toxicology, metabonomics also includes aspects of patho-biochemistry, systems biology, and molecular diagnostics. During a toxicological study, the metabolic changes over time and dose after chemical treatment can be monitored. Therefore, the most important use of this emerging technology is the identification of signatures of toxicity-patterns of metabolic changes predictive of a hazard manifestation. This chapter summarizes the current state of metabonomics technology and its applications in various areas of toxicological studies.

78 FR 45253 - National Toxicology Program Scientific Advisory Committee on Alternative Toxicological Methods...

Science.gov (United States)

2013-07-26

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Toxicology Program... Alternative Methods (ICCVAM), the National Toxicology Program (NTP) Interagency Center for the Evaluation of... Director, National Toxicology Program. [FR Doc. 2013-17919 Filed 7-25-13; 8:45 am] BILLING CODE 4140-01-P ...

Research Article Special Issue

African Journals Online (AJOL)

pc

2018-03-07

Mar 7, 2018 ... Eurostat and the Ministry of Economic Development. 4. .... regard to the application of special national schemes for small enterprises. ... 2013) mentions a two-year exemption from the tax on joint stock companies and local taxes. ... specialized support programs are developed, such as the introduction of the ...

Toxicology Education Foundation

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... bodies and our world. Welcome to the Toxicology Education Foundation! Our mission is to enhance public understanding ... In with us, follow our Tweets, choose Toxicology Education Foundation as your preferred charity through Smile.Amazon. ...

National Toxicology Program

Science.gov (United States)

... NTP? NTP develops and applies tools of modern toxicology and molecular biology to identify substances in the ... depend on for decisions that matter. The National Toxicology Program provides the scientific basis for programs, activities, ...

Special Issue of The Lancet on Sexual and Reproductive Rights and ...

International Development Research Centre (IDRC) Digital Library (Canada)

The Lancet is the world's leading general medical journal and also publishes four monthly ... The special issue will feature research, policy, and program information to ... This group will consist of emerging and renowned population scientists, ... and international processes and events shaping the sexual and reproductive ...

Constrained Agency in Later Working Lives: Introduction to the Special Issue

NARCIS (Netherlands)

Damman, M.; Henkens, K.

2017-01-01

In the social sciences there is an ongoing debate about the primacy of structure or agency in shaping individual behaviors. This Special Issue presents a comprehensive set of papers on structure and agency in the area of later working lives and retirement, specifically focusing on situations where

Introduction to the Special Issue on Climate Ethics: Uncertainty, Values and Policy

OpenAIRE

Roeser, S.

2017-01-01

Climate change is a pressing phenomenon with huge potential ethical, legal and social policy implications. Climate change gives rise to intricate moral and policy issues as it involves contested science, uncertainty and risk. In order to come to scientifically and morally justified, as well as feasible, policies, targeting climate change requires an interdisciplinary approach. This special issue will identify the main challenges that climate change poses from social, economic, methodological ...

Special issue: engineering toxins for 21st-century therapies: introduction.

Science.gov (United States)

Acharya, K Ravi

2011-12-01

This special issue on 'Engineering toxins for 21st century therapies' provides a critical review of the current state of multifaceted aspects of toxin research by some of the leading researchers in the field. It also highlights the clinical potential and challenges for development of novel biologics based on engineered toxin derived products. © 2011 The Author Journal compilation © 2011 FEBS.

Virtual Issue #1: Oil Spill Research in the Bulletin of Environmental Contamination and Toxicology

Science.gov (United States)

The Bulletin of Environmental Contamination and Toxicology has been a venue for publishing oil spill research for over forty years. Rehwoldt et al. (1974) published the first oil spill focused paper in the Bulletin, reporting on the aquatic toxicity of two spill mitigating agents...

Introduction to the Special Issue: Precarious Solidarity-Preferential Access in Canadian Health Care.

Science.gov (United States)

Reid, Lynette

2017-06-01

Systems of universal health coverage may aspire to provide care based on need and not ability to pay; the complexities of this aspiration (conceptual, practical, and ethical) call for normative analysis. This special issue arises in the wake of a judicial inquiry into preferential access in the Canadian province of Alberta, the Vertes Commission. I describe this inquiry and set out a taxonomy of forms of differential and preferential access. Papers in this special issue focus on the conceptual specification of health system boundaries (the concept of medical need) and on the normative questions raised by complex models of funding and delivery of care, where patients, providers, and services cross system boundaries.

Introduction to the special issue on visual working memory.

Science.gov (United States)

Wolfe, Jeremy M

2014-10-01

Visual working memory is a volatile, limited-capacity memory that appears to play an important role in our impression of a visual world that is continuous in time. It also mediates between the contents of the mind and the contents of that visual world. Research on visual working memory has become increasingly prominent in recent years. The articles in this special issue of Attention, Perception, & Psychophysics describe new empirical findings and theoretical understandings of the topic.

EDITORIAL: Special issue on optical micromanipulation

Science.gov (United States)

Heckenberg, N.; Dholakia, K.

2007-08-01

Few would have predicted the impact the laser has had across all of the natural sciences. Laser technology in tandem with microscopy has fuelled a revolutionary advance in biology and chemistry. Microscopic methods permit imaging of cells, nanoparticles, atoms and single molecules. Without doubt, biophotonics has emerged in many guises as a major player on the international arena, and has spawned an industry with an explosive growth rate. Notably, the influence of light is not restricted to passive imaging—it may also move, trap and manoeuvre objects from single atoms right through to the size of a large cell with no damage whatsoever. Given the well-known uses of high power lasers in surgery and industrial cutting, this sounds like science fiction, but at the size scale of these objects it is science fact: it is the area of optical micromanipulation that is the subject of this special issue. The field of optical micromanipulation has continued to impact right across the sciences in an unprecedented fashion, since its inception in the late 1960s. Excitingly the field has made an exceptional impact in single molecule biophysics and the physics of non-equilibrium systems largely due to the fact that an optical trap is an elegant and powerful force transducer. The field is also branching out into new directions: cell biology is benefiting from this advance. Trapping and microfluidics is an exciting combination within the broader remit of the field of optofluidics: methods of multiple traps using diffractive optics are permitting cell sorting, traps are aiding local viscosity measurements and novel biological studies are being performed. Combining traps with other spectroscopic methods and imaging modes is an interesting theme that poses interesting challenges but promises exciting new knowledge. All these areas are represented in this special issue, along with a number of contributions to quantitative modelling of optical fields suitable for trapping and of the

Emerging approaches in predictive toxicology.

Science.gov (United States)

Zhang, Luoping; McHale, Cliona M; Greene, Nigel; Snyder, Ronald D; Rich, Ivan N; Aardema, Marilyn J; Roy, Shambhu; Pfuhler, Stefan; Venkatactahalam, Sundaresan

2014-12-01

Predictive toxicology plays an important role in the assessment of toxicity of chemicals and the drug development process. While there are several well-established in vitro and in vivo assays that are suitable for predictive toxicology, recent advances in high-throughput analytical technologies and model systems are expected to have a major impact on the field of predictive toxicology. This commentary provides an overview of the state of the current science and a brief discussion on future perspectives for the field of predictive toxicology for human toxicity. Computational models for predictive toxicology, needs for further refinement and obstacles to expand computational models to include additional classes of chemical compounds are highlighted. Functional and comparative genomics approaches in predictive toxicology are discussed with an emphasis on successful utilization of recently developed model systems for high-throughput analysis. The advantages of three-dimensional model systems and stem cells and their use in predictive toxicology testing are also described. © 2014 Wiley Periodicals, Inc.

Mass Spectrometry Applications for Toxicology.

Science.gov (United States)

Mbughuni, Michael M; Jannetto, Paul J; Langman, Loralie J

2016-12-01

Toxicology is a multidisciplinary study of poisons, aimed to correlate the quantitative and qualitative relationships between poisons and their physiological and behavioural effects in living systems. Other key aspects of toxicology focus on elucidation of the mechanisms of action of poisons and development of remedies and treatment plans for associated toxic effects. In these endeavours, Mass spectrometry (MS) has become a powerful analytical technique with a wide range of application used in the Toxicological analysis of drugs, poisons, and metabolites of both. To date, MS applications have permeated all fields of toxicology which include; environmental, clinical, and forensic toxicology. While many different analytical applications are used in these fields, MS and its hyphenated applications such as; gas chromatography MS (GC-MS), liquid chromatography MS (LC-MS), inductively coupled plasma ionization MS (ICP-MS), tandem mass spectrometry (MS/MS and MS n ) have emerged as powerful tools used in toxicology laboratories. This review will focus on these hyphenated MS technologies and their applications for toxicology.

Mass Spectrometry Applications for Toxicology

Science.gov (United States)

Mbughuni, Michael M.; Jannetto, Paul J.

2016-01-01

Toxicology is a multidisciplinary study of poisons, aimed to correlate the quantitative and qualitative relationships between poisons and their physiological and behavioural effects in living systems. Other key aspects of toxicology focus on elucidation of the mechanisms of action of poisons and development of remedies and treatment plans for associated toxic effects. In these endeavours, Mass spectrometry (MS) has become a powerful analytical technique with a wide range of application used in the Toxicological analysis of drugs, poisons, and metabolites of both. To date, MS applications have permeated all fields of toxicology which include; environmental, clinical, and forensic toxicology. While many different analytical applications are used in these fields, MS and its hyphenated applications such as; gas chromatography MS (GC-MS), liquid chromatography MS (LC-MS), inductively coupled plasma ionization MS (ICP-MS), tandem mass spectrometry (MS/MS and MSn) have emerged as powerful tools used in toxicology laboratories. This review will focus on these hyphenated MS technologies and their applications for toxicology. PMID:28149262

Special Issue: Next Generation DNA Sequencing

Directory of Open Access Journals (Sweden)

Paul Richardson

2010-10-01

Full Text Available Next Generation Sequencing (NGS refers to technologies that do not rely on traditional dideoxy-nucleotide (Sanger sequencing where labeled DNA fragments are physically resolved by electrophoresis. These new technologies rely on different strategies, but essentially all of them make use of real-time data collection of a base level incorporation event across a massive number of reactions (on the order of millions versus 96 for capillary electrophoresis for instance. The major commercial NGS platforms available to researchers are the 454 Genome Sequencer (Roche, Illumina (formerly Solexa Genome analyzer, the SOLiD system (Applied Biosystems/Life Technologies and the Heliscope (Helicos Corporation. The techniques and different strategies utilized by these platforms are reviewed in a number of the papers in this special issue. These technologies are enabling new applications that take advantage of the massive data produced by this next generation of sequencing instruments. [...

Personality and politics: introduction to the special issue.

Science.gov (United States)

Duncan, Lauren E; Peterson, Bill E; Zurbriggen, Eileen L

2010-12-01

This special issue of Journal of Personality brings together 10 original articles addressing the intersection of personality and politics. Articles build on classic traditions in political psychology by presenting both idiographic and nomothetic work on the motivational, cognitive, ideological, attitudinal, and identity correlates of many different aspects of political behavior. This work is used to understand political activism and leadership as well as everyday political behavior. We hope this collection of articles will inspire our readers to explore new investigations in personality and political psychology. © 2010 The Authors. Journal of Personality © 2010, Wiley Periodicals, Inc.

TOXNET and Beyond-Using the National Library of Medicine's Environmental Health and Toxicology Portal

Energy Technology Data Exchange (ETDEWEB)

Templin-Branner, Wilma

2011-01-01

The purpose of this training is to familiarize participants with reliable online environmental health and toxicology information, from the National Library of Medicine and other reliable sources. Skills and knowledge acquired in this training class will enable participants to access, utilize, and refer others to environmental health and toxicology information. After completing this course, participants will be able to: (1) Identify quality, accurate, and authoritative online resources pertaining to environmental health, toxicology, and related medical information; (2) Demonstrate the ability to perform strategic search techniques to find relevant online information; and (3) Apply the skills and knowledge obtained in this class to their organization's health information needs. NLMs TOXNET (Toxicology Data Network) is a free, Web-based system of databases on toxicology, environmental health, hazardous chemicals, toxic releases, chemical nomenclatures, and specialty areas such as occupational health and consumer products. Types of information in the TOXNET databases include: (1) Specific chemicals, mixtures, and products; (2) Unknown chemicals; and (3) Special toxic effects of chemicals in humans and/or animals.

ACToR-AGGREGATED COMPUTATIONAL TOXICOLOGY ...

Science.gov (United States)

One goal of the field of computational toxicology is to predict chemical toxicity by combining computer models with biological and toxicological data. predict chemical toxicity by combining computer models with biological and toxicological data

Participatory Design in an Era of Participation, Special Issue

DEFF Research Database (Denmark)

This special issue on participatory design in an era of participation presents emerging topics and discussions from the thirteenth Participatory Design conference (PDC), held at Aarhus University in August 2016. The PDC 2016 marked the twenty-fifth anniversary of the Participatory Design conference...... series, which began in 1990 with the first biannual conference in Seattle. Since then, the PDC conferences have continued to bring together a multidisciplinary, international community of researchers and practitioners around issues of cooperative design. The theme for the 2016 PDC conference...... was ‘Participatory Design in an Era of Participation.’ Critical and constructive discussions were invited on the values, characteristics, politics and future practices of participatory design in an era in which participation has now become pervasive (Bossen, Smith, Kanstrup, McDonnell, et al. 2016, Bossen, Smith...

EDITORIAL: Special Issue: CAMOP MOLEC XV

Science.gov (United States)

2006-01-01

The advances in recent years in the field of molecular dynamics are numerous and impressive. In sophisticated experimental and theoretical studies it is nowadays possible to steer chemical reactions with quantum-number-prepared molecules, to study reaction products fully state-specifically, and to derive accurate potential energy surfaces with the goal of determining the pathways along which molecular interaction can take place. Both experimental and theoretical techniques have rapidly improved, and our understanding of the dynamical nature of chemical processes is continuously growing. In this special issue of CAMOP/Physica Scripta we have tried to present a snapshot of the state-of-the-art in the field of molecular dynamics. It contains a collection of papers submitted in association with the most recent MOLEC meeting (MOLEC XV) held in September 2004 in Nunspeet, The Netherlands. This biannual meeting started in 1976 in Trento and was subsequently organized in Brandbjerg Højskole (Denmark, 1978), Oxford (UK, 1980), Nijmegen (The Netherlands, 1982), Jerusalem (Israel, 1984), Aussois (France, 1986), Assissi (Italy, 1988), Bernkastel-Kues (Germany, 1990), Prague (Czech Republic, 1992), Salamanca (Spain, 1994), Nyborg Strand (Denmark, 1996), Bristol (UK, 1998), Jerusalem (Israel, 2000) and Istanbul (Turkey, 2002). Within the philosophy of CAMOP we have asked invited speakers to report on outstanding problems in their particular field. This comprises discussion of open questions, important applications, new theoretical and experimental approaches and also predictions of future developments. A good comment, in addition to being an authoritative contribution of an acknowledged expert, should also be readable by the non-expert and we have taken special care that the work presented here is introduced in an understandable way and has been placed within the context of accessible literature for the interested reader. The sequence of 16 papers that is presented in this

Progress in computational toxicology.

Science.gov (United States)

Ekins, Sean

2014-01-01

Computational methods have been widely applied to toxicology across pharmaceutical, consumer product and environmental fields over the past decade. Progress in computational toxicology is now reviewed. A literature review was performed on computational models for hepatotoxicity (e.g. for drug-induced liver injury (DILI)), cardiotoxicity, renal toxicity and genotoxicity. In addition various publications have been highlighted that use machine learning methods. Several computational toxicology model datasets from past publications were used to compare Bayesian and Support Vector Machine (SVM) learning methods. The increasing amounts of data for defined toxicology endpoints have enabled machine learning models that have been increasingly used for predictions. It is shown that across many different models Bayesian and SVM perform similarly based on cross validation data. Considerable progress has been made in computational toxicology in a decade in both model development and availability of larger scale or 'big data' models. The future efforts in toxicology data generation will likely provide us with hundreds of thousands of compounds that are readily accessible for machine learning models. These models will cover relevant chemistry space for pharmaceutical, consumer product and environmental applications. Copyright © 2013 Elsevier Inc. All rights reserved.

Special Education for Children with Attention Deficit Disorder: Current Issues. CRS Report for Congress.

Science.gov (United States)

Aleman, Steven R.

This paper examines issues concerning the eligibility of children with attention deficit disorder (ADD) for special education and related services under the Individuals with Disabilities Education Act (IDEA). A policy memorandum was issued by the Department of Education in September 1991, identifying those circumstances under which such children…

The century of the sun starts in the year 2000. Special issue

International Nuclear Information System (INIS)

Janse, F.; De Vries, E.; Brandsma, M.; Wiezer, F.

1997-01-01

In this special issue of the magazine a large number of brief articles on several aspects of solar energy is presented. In particular thermal solar energy has reached a phase from where a breakthrough is only a matter of some years

Special issue on new ideas and emerging results in understanding software

NARCIS (Netherlands)

Vinju, J.J.

2015-01-01

Welcome to the special issue on new ideas and emerging results in understanding software. It is a present to Prof. Dr. Paul Klint on the occasion of his 65th birthday. His colleagues and friends who share similar research interests have written the papers, wanting to present Paul with a worthy gift.

Introduction to the Special Issue on the Theory of Human Values

Directory of Open Access Journals (Sweden)

Eldad Davidov

2012-04-01

Full Text Available Research on human values in the social sciences took of after Schwartz introduced his theory of basic human values in 1992. This special issue includes articles dealing with methods of data analysis applied to measurements of some or all of the values postulated by the theory and of other variables.

Editorial: AABFJ Volume 8, Issue 4 Special Issue in Financial Markets and Financial Instruments

Directory of Open Access Journals (Sweden)

Ciorstan Smark

2014-10-01

Full Text Available Financial planning in Australia is in a time of change and challenge. Educational standards and regulation are in flux. There is a strong need to move financial planning into a more esteemed professional position as financial planners are not always considered the safest source of advice for people in Asia and the pacific rim when it comes to investing their much needed retirement funds. This Special Issue on Financial Planning and Financial Instruments brings together articles from financial planning, banking, financial markets and retirement policy.

The U.S. National Library of Medicine's Toxicology and Environmental Health Information Program

International Nuclear Information System (INIS)

Wexler, Philip

2004-01-01

For nearly 40 years, the National Library of Medicine's (NLM) Toxicology and Environmental Health Information Program (TEHIP) has been a significant leader in organizing and providing public access to an extensive storehouse of toxicological information through its online databases. With the advent of the Internet, TEHIP has expanded its role to also serve as a pre-eminent portal to toxicological information worldwide. Its primary databases reside within the web-based TOXNET system, and include the scientifically peer-reviewed Hazardous Substances Data Bank (HSDB), the U.S. Environmental Protection Agency's Integrated Risk Information System (IRIS) and Toxics Release Inventory, the National Cancer Institute's Chemical Carcinogenesis Research Information System (CCRIS) and the TOXLINE file of over 3 million bibliographic references. TEHIP's ChemIDplus is an extensive chemical dictionary that extends beyond simple nomenclature to offer displays of molecular structures and links from particular chemicals to other databases containing more information. Specialty files in occupational safety and health, and household products have recently been added to TEHIP's suite of resources. Additional databases in risk assessment, drugs, toxicology education, and global resources, are under development. ''Special Topics'' pages lead users to structured summaries and links in areas such as arsenic, chemical warfare agents, biological warfare, and West Nile Virus. A database on alternatives to the use of live animals, a three-module toxicology tutor, and a glossary of terms in toxicology are among TEHIP's other information aids, as well an increasing commitment to serving consumers, as witnessed by the animated ToxTown program. Outside the sphere of TEHIP, NLM offers additional databases, such as PubMed, of significant value to toxicology researchers

Introduction to the Social Media + Society Special Issue on Selfies: Me-diated Inter-faces

Directory of Open Access Journals (Sweden)

Katie Warfield

2016-04-01

Full Text Available This introduction to the special issue entitled Me-diated Inter-faces begins by bringing into question the concept of positioning: what is it that we are doing when we take a position within the study of social media? Reviewing the work of the inaugural manifestos of the journal Social Media + Society on one hand, and the introduction to the special issue on selfies for the International Journal of Communications on the other, this introduction provides both critical and creative in-roads for thinking and re-thinking digital self-images shared on social media. Given the constantly changing nature of social media, this paper is a call to researchers of social media to not fall prey to the ossification of our current positions since theorizing the “social” in social media means always at once theorizing the body. As such this intro offers numerous and diverse perspectives on the body that might inform emerging thoughts on the socially media body. The introduction then provides an overview of the papers in this special issue and concludes by offering openings and ruptures for further discussion, rather than closure of conclusions.

EDITORIAL: Special issue on silicon photonics

Science.gov (United States)

Reed, Graham; Paniccia, Mario; Wada, Kazumi; Mashanovich, Goran

2008-06-01

mechanisms for modulation in silicon that have yielded increasingly impressive results (see, for example, Liao L et al 2007 Electron. Lett. 43 issue 22). The convergence of computing and communications and the resultant demand for increased bandwidth has been one of the factors influencing the upsurge of interest in silicon, together with the requirement for photonic and electronic integration, all to be realized at low cost. Thus emerging applications such as short-reach communications links for optical interconnect and fibre to the home (FTTH) (as well as a multitude of other applications) are frequently offered as examples of where silicon photonics will have a significant, perhaps a revolutionary, impact. One of the major conclusions of the joint MIT-industry Communication Technology Roadmap (http://mph-roadmap.mit.edu/index.php), was that 'Photonics technology will be driven by electronic-photonic synergy and short (intelligence. Thus the limitations of silicon as an optical material can be offset against the very significant advantages, to both commercial as well as technological success. Of course, there is still much to do, hence the increasing global investment in silicon technology and the massive increase in research activity in silicon photonics since the early work in the 1980s. Only time will tell if silicon can realize its potential to satisfy the ever-increasing array of applications. However, the indications are positive, and the contributors to this cause employ increasingly impressive levels of intellectual and technological capability to realize the desired goals. It is an interesting time to be involved in slicon photonics, and it will be equally fascinating to watch the evolution of the technology in the future. Whatever happens, silicon will make the transition from being regarded as purely an electronic material to recognition as an optoelectronic material. The evidence for this is represented in the collection of papers that form this special issue

Risk assessment and toxicology databases for health effects assessment

Energy Technology Data Exchange (ETDEWEB)

Lu, P.Y.; Wassom, J.S. [Oak Ridge National Laboratory, TN (United States)

1990-12-31

Scientific and technological developments bring unprecedented stress to our environment. Society has to predict the results of potential health risks from technologically based actions that may have serious, far-reaching consequences. The potential for error in making such predictions or assessment is great and multiplies with the increasing size and complexity of the problem being studied. Because of this, the availability and use of reliable data is the key to any successful forecasting effort. Scientific research and development generate new data and information. Much of the scientific data being produced daily is stored in computers for subsequent analysis. This situation provides both an invaluable resource and an enormous challenge. With large amounts of government funds being devoted to health and environmental research programs and with maintenance of our living environment at stake, we must make maximum use of the resulting data to forecast and avert catastrophic effects. Along with the readily available. The most efficient means of obtaining the data necessary for assessing the health effects of chemicals is to utilize applications include the toxicology databases and information files developed at ORNL. To make most efficient use of the data/information that has already been prepared, attention and resources should be directed toward projects that meticulously evaluate the available data/information and create specialized peer-reviewed value-added databases. Such projects include the National Library of Medicine`s Hazardous Substances Data Bank, and the U.S. Air Force Installation Restoration Toxicology Guide. These and similar value-added toxicology databases were developed at ORNL and are being maintained and updated. These databases and supporting information files, as well as some data evaluation techniques are discussed in this paper with special focus on how they are used to assess potential health effects of environmental agents. 19 refs., 5 tabs.

PREFACE: Celebrating 100 years of superconductivity: special issue on the iron-based superconductors Celebrating 100 years of superconductivity: special issue on the iron-based superconductors

Science.gov (United States)

Crabtree, George; Greene, Laura; Johnson, Peter

2011-12-01

In honor of this year's 100th anniversary of the discovery of superconductivity, this special issue of Reports on Progress in Physics is a dedicated issue to the 'iron-based superconductors'—a new class of high-temperature superconductors that were discovered in 2008. This is the first time the journal has generated a 'theme issue', and we provide this to the community to provide a 'snapshot' of the present status, both for researchers working in this fast-paced field, and for the general physics community. Reports on Progress in Physics publishes three classes of articles—comprehensive full Review Articles, Key Issues Reviews and, most recently, Reports on Progress articles that recount the current status of a rapidly evolving field, befitting of the articles in this special issue. It has been an exciting year for superconductivity—there have been numerous celebrations for this centenary recounting the fascinating history of this field, from seven Nobel prizes to life-saving discoveries that brought us medically useful magnetic resonance imaging. The discovery of a completely new class of high-temperature superconductors, whose mechanism remains as elusive as the cuprates discovered in 1986, has injected a new vitality into this field, and this year those new to the field were provided with the opportunity of interacting with those who have enjoyed a long history in superconductivity. Furthermore, as high-density current carriers with little or no power loss, high-temperature superconductors offer unique solutions to fundamental grid challenges of the 21st century and hold great promise in addressing our global energy challenges. The complexity and promise of these materials has caused our community to more freely share our ideas and results than ever before, and it is gratifying to see how we have grown into an enthusiastic global network to advance the field. This invited collection is true to this agenda and we are delighted to have received contributions

Editorial for special issue on Perception and Navigation for Autonomous Vehicles

OpenAIRE

Laugier , Christian; Philippe , Martinet; Urbano , Nunes

2014-01-01

International audience; This Special Issue of the IEEE Robotics and Automation Magazine has been prepared in the scope of the activities of the Technical Committee on "Autonomous Ground Vehicle and Intelligent Transportation System" (AGV-ITS) (http://www.ieee-ras.org/autonomous-groundvehicles- and-intelligent-transportation-systems) of the IEEE Robotics and Automation Society (IEEE RAS).

Religious, Secular, and Spiritual Identities Convergence: Introduction to the Special Issue

Science.gov (United States)

Small, Jenny L.; Bowman, Nicholas A.

2018-01-01

The purpose of this special issue is to share the best research, theory, practice, and perspectives from presenters at the 2017 Religious, Secular, and Spiritual Identities Convergence conference, alongside the new writing of scholars and practitioners who were inspired by the themes of the conference. Readers will have access both to the best of…

Environmental Toxicology Research Facility

Data.gov (United States)

Federal Laboratory Consortium — Fully-equipped facilities for environmental toxicology researchThe Environmental Toxicology Research Facility (ETRF) located in Vicksburg, MS provides over 8,200 ft...

Foreword of Special Issue on “Nomadic Services and Applications”

OpenAIRE

Jason C. Hung

2011-01-01

Nomadic Service has emerged rapidly as an exciting new paradigm that offers a challenging model of cyber-physical services and poses fascinating problems regarding distributed resource management, ranging from information sharing to cooperative computing. This special issue is intended to foster state-of-the-art research in the area of nomadic services and related applications, cloud computing technologies and services, including the topics of collaboration environment, implementation and exe...

2012 Special NSREC Issue of the IEEE Transactions on Nuclear Science Comments by the Editors

Science.gov (United States)

Schwank, Jim; Brown, Dennis; Girard, Sylvain; Gouker, Pascale; Gerardin, Simone; Quinn, Heather; Barnaby, Hugh

2012-12-01

The December 2012 special issue of the IEEE Transactions on Nuclear Science contains selected papers from the 49th annual IEEE International Nuclear and Space Radiation Effects Conference (NSREC) held July 16-20, 2012, in Miami, Florida USA. 95 papers presented at the 2012 NSREC were submitted for consideration for this year’s special issue. Those papers that appear in this special issue were able to successfully complete the review process before the deadline for the December issue. A few additional papers may appear in subsequent issues of the TRANSACTIONS. This publication is the premier archival journal for research on space and nuclear radiation effects in materials, devices, circuits, and systems. This distinction is the direct result of the conscientious efforts of both the authors, who present and document their work, and the reviewers, who selflessly volunteer their time and talent to help review the manuscripts. Each paper in this journal has been reviewed by experts selected by the editors for their expertise and knowledge of the particular subject areas. The peer review process for a typical technical journal generally takes six months to one year to complete. To publish this special issue of the IEEE Transactions on Nuclear Science (in December), the review process, from initial submission to final form, must be completed in about 10 weeks. Because of the short schedule, both the authors and reviewers are required to respond very quickly. The reviewers listed on the following pages contributed vitally to this quick-turn review process.We would like to express our sincere appreciation to each of them for accepting this difficult, but critical role in the process. To provide consistent reviews of papers throughout the year, the IEEE Transactions on Nuclear Science relies on a year-round editorial board that manages reviews for submissions throughout the year to the TRANSACTIONS in the area of radiation effects. The review process is managed by a Senior

Psychology of Game Playing: Introduction to a Special Issue

Directory of Open Access Journals (Sweden)

Andrew M. Colman

2015-12-01

Full Text Available Game theory has focused attention on different problems at different times in its history. Currently, attention is devoted to investigating how human decision makers with bounded rationality choose strategies in interactive decisions. Behavioral economics, and more generally experimental games, have appeared in the literature with accelerating frequency since 1990, and this cannot continue indefinitely without a proportional expansion of journal space. This Special Issue includes contributions to behavioral economics, experimental games, and evolutionary game theory, using theoretical, experimental, and agent-based modeling techniques.

Waste management in space: a NASA symposium. Special issue

Science.gov (United States)

Wydeven, T. (Principal Investigator)

1991-01-01

This special issue contains papers from the NASA Symposium on Waste Processing for Advanced Life Support, which was held at NASA Ames Research Center on September 11-13, 1990. Specialists in waste management from academia, government, and industry convened to exchange ideas and advise NASA in developing effective methods for waste management in a Controlled Ecological Life Support System (CELSS). Innovative and well-established methods were presented to assist in developing and managing wastes in closed systems for future long-duration space missions, especially missions to Mars.

Preface paper to the Semi-Arid Land-Surface-Atmosphere (SALSA) Program special issue

Science.gov (United States)

Goodrich, D.C.; Chehbouni, A.; Goff, B.; MacNish, B.; Maddock, T.; Moran, S.; Shuttleworth, W.J.; Williams, D.G.; Watts, C.; Hipps, L.H.; Cooper, D.I.; Schieldge, J.; Kerr, Y.H.; Arias, H.; Kirkland, M.; Carlos, R.; Cayrol, P.; Kepner, W.; Jones, B.; Avissar, R.; Begue, A.; Bonnefond, J.-M.; Boulet, G.; Branan, B.; Brunel, J.P.; Chen, L.C.; Clarke, T.; Davis, M.R.; DeBruin, H.; Dedieu, G.; Elguero, E.; Eichinger, W.E.; Everitt, J.; Garatuza-Payan, J.; Gempko, V.L.; Gupta, H.; Harlow, C.; Hartogensis, O.; Helfert, M.; Holifield, C.; Hymer, D.; Kahle, A.; Keefer, T.; Krishnamoorthy, S.; Lhomme, J.-P.; Lagouarde, J.-P.; Lo, Seen D.; Luquet, D.; Marsett, R.; Monteny, B.; Ni, W.; Nouvellon, Y.; Pinker, R.; Peters, C.; Pool, D.; Qi, J.; Rambal, S.; Rodriguez, J.; Santiago, F.; Sano, E.; Schaeffer, S.M.; Schulte, M.; Scott, R.; Shao, X.; Snyder, K.A.; Sorooshian, S.; Unkrich, C.L.; Whitaker, M.; Yucel, I.

2000-01-01

The Semi-Arid Land-Surface-Atmosphere Program (SALSA) is a multi-agency, multi-national research effort that seeks to evaluate the consequences of natural and human-induced environmental change in semi-arid regions. The ultimate goal of SALSA is to advance scientific understanding of the semi-arid portion of the hydrosphere-biosphere interface in order to provide reliable information for environmental decision making. SALSA approaches this goal through a program of long-term, integrated observations, process research, modeling, assessment, and information management that is sustained by cooperation among scientists and information users. In this preface to the SALSA special issue, general program background information and the critical nature of semi-arid regions is presented. A brief description of the Upper San Pedro River Basin, the initial location for focused SALSA research follows. Several overarching research objectives under which much of the interdisciplinary research contained in the special issue was undertaken are discussed. Principal methods, primary research sites and data collection used by numerous investigators during 1997-1999 are then presented. Scientists from about 20 US, five European (four French and one Dutch), and three Mexican agencies and institutions have collaborated closely to make the research leading to this special issue a reality. The SALSA Program has served as a model of interagency cooperation by breaking new ground in the approach to large scale interdisciplinary science with relatively limited resources.

Editorial: 2nd Special Issue on behavior change, health, and health disparities.

Science.gov (United States)

Higgins, Stephen T

2015-11-01

This Special Issue of Preventive Medicine (PM) is the 2nd that we have organized on behavior change, health, and health disparities. This is a topic of fundamental importance to improving population health in the U.S. and other industrialized countries that are trying to more effectively manage chronic health conditions. There is broad scientific consensus that personal behavior patterns such as cigarette smoking, other substance abuse, and physical inactivity/obesity are among the most important modifiable causes of chronic disease and its adverse impacts on population health. As such behavior change needs to be a key component of improving population health. There is also broad agreement that while these problems extend across socioeconomic strata, they are overrepresented among more economically disadvantaged populations and contribute directly to the growing problem of health disparities. Hence, behavior change represents an essential step in curtailing that unsettling problem as well. In this 2nd Special Issue, we devote considerable space to the current U.S. prescription opioid addiction epidemic, a crisis that was not addressed in the prior Special Issue. We also continue to devote attention to the two largest contributors to preventable disease and premature death, cigarette smoking and physical inactivity/obesity as well as risks of co-occurrence of these unhealthy behavior patterns. Across each of these topics we included contributions from highly accomplished policy makers and scientists to acquaint readers with recent accomplishments as well as remaining knowledge gaps and challenges to effectively managing these important chronic health problems. Copyright © 2015 Elsevier Inc. All rights reserved.

Introduction to the Special Issue on Gender and Geoethics in the Geosciences.

Science.gov (United States)

Thornbush, Mary

2016-04-01

In this introduction to the Special Issue on Gender and Geoethics in the Geosciences is a focus on the participation of women in traditionally male-dominated professions, with geography as an exemplary academic subject. The Special Issue stems from the Commission of Gender and Geoethics as part of the International Association of Geoethics, and endeavors to bring together efforts at various spatial scales that examine the position of women in science and engineering in particular, as conveyed in engineering geology, disaster management sciences, and climate change adaptation studies. It has been discovered, for instance, that men are more active and personally prepared at the community level (in Atlantic Canada coastal communities), and more action is still required in developing countries especially to promote gender equality and empower women. Studies contained in this Special Issue also reveal that tutoring and mentoring by other women can promote further involvement in non-traditional professions, such as professional engineering geology, where women are preferring more traditional (less applied) approaches that may circumscribe their ability to find suitable employment after graduation. Moreover, the hiring policy needs to change in many countries, such as Canada, where there are fewer women at entry-level and senior ranks within geography, especially in physical geography as the scientific part of the discipline. The exclusion of women in traditionally male-dominated spheres needs to be addressed and rectified for the ascent of women to occur in scientific geography and in other geosciences as well as science and engineering at large.

Introduction to the Special Issue on Gender and Geoethics in the Geosciences

Directory of Open Access Journals (Sweden)

Mary Thornbush

2016-04-01

Full Text Available In this introduction to the Special Issue on Gender and Geoethics in the Geosciences is a focus on the participation of women in traditionally male-dominated professions, with geography as an exemplary academic subject. The Special Issue stems from the Commission of Gender and Geoethics as part of the International Association of Geoethics, and endeavors to bring together efforts at various spatial scales that examine the position of women in science and engineering in particular, as conveyed in engineering geology, disaster management sciences, and climate change adaptation studies. It has been discovered, for instance, that men are more active and personally prepared at the community level (in Atlantic Canada coastal communities, and more action is still required in developing countries especially to promote gender equality and empower women. Studies contained in this Special Issue also reveal that tutoring and mentoring by other women can promote further involvement in non-traditional professions, such as professional engineering geology, where women are preferring more traditional (less applied approaches that may circumscribe their ability to find suitable employment after graduation. Moreover, the hiring policy needs to change in many countries, such as Canada, where there are fewer women at entry-level and senior ranks within geography, especially in physical geography as the scientific part of the discipline. The exclusion of women in traditionally male-dominated spheres needs to be addressed and rectified for the ascent of women to occur in scientific geography and in other geosciences as well as science and engineering at large.

Introduction to the Special Issue on Gender and Geoethics in the Geosciences

Science.gov (United States)

Thornbush, Mary

2016-01-01

In this introduction to the Special Issue on Gender and Geoethics in the Geosciences is a focus on the participation of women in traditionally male-dominated professions, with geography as an exemplary academic subject. The Special Issue stems from the Commission of Gender and Geoethics as part of the International Association of Geoethics, and endeavors to bring together efforts at various spatial scales that examine the position of women in science and engineering in particular, as conveyed in engineering geology, disaster management sciences, and climate change adaptation studies. It has been discovered, for instance, that men are more active and personally prepared at the community level (in Atlantic Canada coastal communities), and more action is still required in developing countries especially to promote gender equality and empower women. Studies contained in this Special Issue also reveal that tutoring and mentoring by other women can promote further involvement in non-traditional professions, such as professional engineering geology, where women are preferring more traditional (less applied) approaches that may circumscribe their ability to find suitable employment after graduation. Moreover, the hiring policy needs to change in many countries, such as Canada, where there are fewer women at entry-level and senior ranks within geography, especially in physical geography as the scientific part of the discipline. The exclusion of women in traditionally male-dominated spheres needs to be addressed and rectified for the ascent of women to occur in scientific geography and in other geosciences as well as science and engineering at large. PMID:27043609

21 CFR 862.3200 - Clinical toxicology calibrator.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Clinical toxicology calibrator. 862.3200 Section... (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES Clinical Toxicology Test Systems § 862.3200 Clinical toxicology calibrator. (a) Identification. A clinical toxicology calibrator is...

Information resources in toxicology--Italy

International Nuclear Information System (INIS)

Preziosi, Paolo; Dracos, Adriana; Marcello, Ida

2003-01-01

The purpose of the present paper is to provide an overview of current resources in the field of toxicology in Italy. The discussion will begin with a brief history of toxicology in this country, which includes the study of the toxicity of plants and other natural substances, and the birth of industrial and forensic toxicology. We will also provide information on research, education, and hazard control in the field of toxicology. Within this context we will examine the public bodies responsible for surveillance and regulatory activities, state-owned and private structures involved in toxicological research, and the educational programs and research activities of universities. Particular emphasis will be placed on the activities of the National Health Service, which plays an important role in areas such as clinical toxicology, food safety, and animal health, as well as those of national and regional agencies dedicated to the protection of the environment. The presentation will be organized as follows: - A Brief History of Toxicology in Italy; - Professional Societies; - National Health Service; - National Bodies; - Resources for the Environment; - Biomedical Websites; - Recent Publications; - Research Structures; - Graduate and Postgraduate Programs; - Legislation

Handbook of systems toxicology

National Research Council Canada - National Science Library

Casciano, Daniel A; Sahu, Saura C

2011-01-01

"In the first handbook to comprehensively cover the emerging area of systems toxicology, the Handbook of Systems Toxicology provides an authoritative compilation of up-to-date developments presented...

Introduction to the Special Issue: New and Interdisciplinary Approaches to Linguistic Relativity

Science.gov (United States)

Athanasopoulos, Panos; Bylund, Emanuel; Casasanto, Daniel

2016-01-01

This Special Issue of "Language Learning" presents an interdisciplinary state-of-the-art overview of current approaches to linguistic relativity. It contains empirical and theoretical studies and reflections on linguistic relativity from a variety of perspectives, such as associative learning, conceptual transfer, multilingual awareness,…

HEALTH AND ENVIRONMENTAL IMPACT OF NANOTECHNOLOGY: TOXICOLOGICAL ASSESSMENT OF MANUFACTURED NANOPARTICLES

Science.gov (United States)

The microtechnology of the second half of the 20th century has produced a technical revolution that has lead to the production of computers, the Internet and taken us into a new emerging era of nanotechnology. This issue of Toxicological Sciences includes two articles, "Pulmonar...

Current Issues in the Neurology and Genetics of Learning-Related Traits and Disorders: Introduction to the Special Issue.

Science.gov (United States)

Gilger, Jeffrey W.

2001-01-01

This introductory article briefly describes each of the following eight articles in this special issue on the neurology and genetics of learning related disorders. It notes the greater appreciation of learning disability as a set of complex disorders with broad and intricate neurological bases and of the large individual differences in how these…

Waste tank safety program annual status report for FY 1993, Task 5: Toxicology and epidemiology

International Nuclear Information System (INIS)

Mahlum, D.D.; Young, J.Y.

1993-09-01

A toxicology team independently reviewed analytical data and provided advice concerning potential health effects associated with exposure to tank-vapor constituents at the Hanford site. Most of the emphasis was directed toward Tank 241-C-103, but a preliminary assessment was also made of the toxicologic implication of the cyanide levels in the headspace of Tank 241-C-108. The objectives of this program are to (1) review procedures used for sampling vapors from various tanks, (2) identify constituents in tank-vapor samples that could be related to symptoms reported by waste-tank workers, (3) evaluate the toxicologic implications of those constituents by comparison to established toxicologic data bases, (4) provide advice for additional analytical efforts, and (5) support other activities as requested by the project manager and the cognizant Westinghouse Hanford Company Tank Vapor Issues Safety Resolution Manager

42 CFR 493.937 - Toxicology.

Science.gov (United States)

2010-10-01

... 42 Public Health 5 2010-10-01 2010-10-01 false Toxicology. 493.937 Section 493.937 Public Health... Proficiency Testing Programs by Specialty and Subspecialty § 493.937 Toxicology. (a) Program content and frequency of challenge. To be approved for proficiency testing for toxicology, the annual program must...

Editorial: 3rd Special Issue on behavior change, health, and health disparities.

Science.gov (United States)

Higgins, Stephen T

2016-11-01

This Special Issue of Preventive Medicine (PM) is the 3rd that we have organized on behavior change, health, and health disparities. This is a topic of critical importance to improving U.S. population health. There is broad scientific consensus that personal behaviors such as cigarette smoking, other substance abuse, and physical inactivity/obesity are among the most important modifiable causes of chronic disease and its adverse impacts on population health. Hence, effectively promoting health-related behavior change needs to be a key component of health care research and policy. There is also broad recognition that while these problems extend throughout the population, they disproportionately impact economically disadvantaged populations and other vulnerable populations and represent a major contributor to health disparities. Thus, behavior change represents an essential step in curtailing health disparities, which receives special attention in this 3rd Special Issue. We also devote considerable space to the longstanding challenges of reducing cigarette smoking and use of other tobacco and nicotine delivery products in vulnerable populations, obesity, and for the first time food insecurity. Across each of these topics we include contributions from highly accomplished policymakers and scientists to acquaint readers with recent accomplishments as well as remaining knowledge gaps and challenges. Copyright © 2016 Elsevier Inc. All rights reserved.

Workplace learning: panacea or challenge? : Epilogue of a special issue on boundaries of workplace learning

NARCIS (Netherlands)

Dr. J. Onstenk

2012-01-01

This article reflects on the previous articles in this special issue by discussing some common themes and raising some proposals for future research on the topic of workplace learning and its boundaries. The article subsequently discusses objects and results of workplace learning, the issue of

Toxicological awakenings: the rebirth of hormesis as a central pillar of toxicology

International Nuclear Information System (INIS)

Calabrese, Edward J.

2005-01-01

This paper assesses historical reasons that may account for the marginalization of hormesis as a dose-response model in the biomedical sciences in general and toxicology in particular. The most significant and enduring explanatory factors are the early and close association of the concept of hormesis with the highly controversial medical practice of homeopathy and the difficulty in assessing hormesis with high-dose testing protocols which have dominated the discipline of toxicology, especially regulatory toxicology. The long-standing and intensely acrimonious conflict between homeopathy and 'traditional' medicine (allopathy) lead to the exclusion of the hormesis concept from a vast array of medical- and public health-related activities including research, teaching, grant funding, publishing, professional societal meetings, and regulatory initiatives of governmental agencies and their advisory bodies. Recent publications indicate that the hormetic dose-response is far more common and fundamental than the dose-response models [threshold/linear no threshold (LNT)] used in toxicology and risk assessment, and by governmental regulatory agencies in the establishment of exposure standards for workers and the general public. Acceptance of the possibility of hormesis has the potential to profoundly affect the practice of toxicology and risk assessment, especially with respect to carcinogen assessment

Special issue review of pollution prevention management within the Department of Energy, final report

International Nuclear Information System (INIS)

1994-08-01

The Department of Energy's (DOE) national role and overall mission has been undergoing significant change. In the post-Cold War era, a new emphasis on cleaning up the wastes from the past has emerged. These changes provide both significant challenges as well as new opportunities for DOE. While the challenges may seem overwhelming as DOE realizes the magnitude of its environmental problems, its network of national laboratories and sites provide the resources to become a leader in environmental management through the development of new technologies and management practices. Because of the growing importance of pollution prevention in the United States and more specifically to DOE's environmental management strategy, the Office of Environmental Audit (EH-24) identified this as an area worthy of a Special Issue Review. A Special Issue Review is not an audit but rather an in-depth review of key environmental programs or activities which cut across organizational boundaries. The purpose of a Special Issue Review is to identify strengths and weaknesses of a program as well as significant crosscutting issues or challenges that are important to the future success of that program. The scope of the review included an assessment of pollution prevention program activities at Headquarters, selected operations offices, and selected sites offices and contractor organizations. All aspects of a pollution prevention program were considered including program strategy, infrastructure, management systems, and implementation practices. Also summarized are future pollution prevention challenges and recommendations

SPECIAL ISSUE VETERINARY IMMUNOLOGY IMMUNOPATHOLOGY: PROCEEDINGS 8TH INTERNATIONAL VETERINARY IMMUNOLOGY SYMPOSIUM

Science.gov (United States)

This is the Special Issue of Vet. Immunol. Immunopathol. that summarizes the 8th International Veterinary Immunology Symposium (8 th IVIS) held August 15th-19th, 2007, in Ouro Preto, Brazil. The 8 th IVIS highlighted the importance of veterinary immunology for animal health, vaccinology, reproducti...

COMPUTATIONAL TOXICOLOGY-WHERE IS THE DATA? ...

Science.gov (United States)

This talk will briefly describe the state of the data world for computational toxicology and one approach to improve the situation, called ACToR (Aggregated Computational Toxicology Resource). This talk will briefly describe the state of the data world for computational toxicology and one approach to improve the situation, called ACToR (Aggregated Computational Toxicology Resource).

Pocket atlas of toxicology. Substances, effects, environment. 2. ed.; Taschenatlas der Toxikologie. Substanzen, Wirkungen, Umwelt

Energy Technology Data Exchange (ETDEWEB)

Reichl, F.X. (ed.)

2002-07-01

The revised and enhanced edition of this atlas explains and illustrates the effects of substances with ecological effects that may be harmful to vegetation, animals, and humans. The most recent findings in this respect are taken into account. Risk assessments in case of exposure are made by competent experts and in consideration of the most recent limiting values, enabling the interested lay public to assess environmental hazards on their own. What makes the book particularly valuable is the mention of most recent findings, e.g. newly discovered poisonous birds and mammals and their toxic effects. The former two-section structure of the book has been retained. The first part (general toxicology) contains updated fundamental information on toxicokinetics, toxicodynamics, test methods, aspects of clinical toxicology, and new findings of environmental medicine and environmental toxicology. In the second part (special toxicology), the various groups of noxious and toxic substances are presented, including the effects of radiation and noise. Current limiting values are presented for pollutants and environmental factors that facilitate risk assessment in case of exposure. (orig.)

In silico toxicology protocols.

Science.gov (United States)

Myatt, Glenn J; Ahlberg, Ernst; Akahori, Yumi; Allen, David; Amberg, Alexander; Anger, Lennart T; Aptula, Aynur; Auerbach, Scott; Beilke, Lisa; Bellion, Phillip; Benigni, Romualdo; Bercu, Joel; Booth, Ewan D; Bower, Dave; Brigo, Alessandro; Burden, Natalie; Cammerer, Zoryana; Cronin, Mark T D; Cross, Kevin P; Custer, Laura; Dettwiler, Magdalena; Dobo, Krista; Ford, Kevin A; Fortin, Marie C; Gad-McDonald, Samantha E; Gellatly, Nichola; Gervais, Véronique; Glover, Kyle P; Glowienke, Susanne; Van Gompel, Jacky; Gutsell, Steve; Hardy, Barry; Harvey, James S; Hillegass, Jedd; Honma, Masamitsu; Hsieh, Jui-Hua; Hsu, Chia-Wen; Hughes, Kathy; Johnson, Candice; Jolly, Robert; Jones, David; Kemper, Ray; Kenyon, Michelle O; Kim, Marlene T; Kruhlak, Naomi L; Kulkarni, Sunil A; Kümmerer, Klaus; Leavitt, Penny; Majer, Bernhard; Masten, Scott; Miller, Scott; Moser, Janet; Mumtaz, Moiz; Muster, Wolfgang; Neilson, Louise; Oprea, Tudor I; Patlewicz, Grace; Paulino, Alexandre; Lo Piparo, Elena; Powley, Mark; Quigley, Donald P; Reddy, M Vijayaraj; Richarz, Andrea-Nicole; Ruiz, Patricia; Schilter, Benoit; Serafimova, Rositsa; Simpson, Wendy; Stavitskaya, Lidiya; Stidl, Reinhard; Suarez-Rodriguez, Diana; Szabo, David T; Teasdale, Andrew; Trejo-Martin, Alejandra; Valentin, Jean-Pierre; Vuorinen, Anna; Wall, Brian A; Watts, Pete; White, Angela T; Wichard, Joerg; Witt, Kristine L; Woolley, Adam; Woolley, David; Zwickl, Craig; Hasselgren, Catrin

2018-04-17

The present publication surveys several applications of in silico (i.e., computational) toxicology approaches across different industries and institutions. It highlights the need to develop standardized protocols when conducting toxicity-related predictions. This contribution articulates the information needed for protocols to support in silico predictions for major toxicological endpoints of concern (e.g., genetic toxicity, carcinogenicity, acute toxicity, reproductive toxicity, developmental toxicity) across several industries and regulatory bodies. Such novel in silico toxicology (IST) protocols, when fully developed and implemented, will ensure in silico toxicological assessments are performed and evaluated in a consistent, reproducible, and well-documented manner across industries and regulatory bodies to support wider uptake and acceptance of the approaches. The development of IST protocols is an initiative developed through a collaboration among an international consortium to reflect the state-of-the-art in in silico toxicology for hazard identification and characterization. A general outline for describing the development of such protocols is included and it is based on in silico predictions and/or available experimental data for a defined series of relevant toxicological effects or mechanisms. The publication presents a novel approach for determining the reliability of in silico predictions alongside experimental data. In addition, we discuss how to determine the level of confidence in the assessment based on the relevance and reliability of the information. Copyright © 2018. Published by Elsevier Inc.

Postmortem aviation forensic toxicology: an overview.

Science.gov (United States)

Chaturvedi, Arvind K

2010-05-01

An overview of the subtopic aviation combustion toxicology of the field of aerospace toxicology has been published. In a continuation of the overview, the findings associated with postmortem aviation forensic toxicology are being summarized in the present overview. A literature search for the period of 1960-2007 was performed. The important findings related to postmortem toxicology were evaluated. In addition to a brief introduction, this overview is divided into the sections of analytical methods; carboxyhemoglobin and blood cyanide ion; ethanol; drugs; result interpretation; glucose and hemoglobin A(1c); and references. Specific details of the subject matter were discussed. It is anticipated that this overview will be an outline source for aviation forensic toxicology within the field of aerospace toxicology.

Building bridges between clinical and forensic toxicology laboratories.

Science.gov (United States)

Martin, Bernardino Barcelo; Gomila, Isabel; Noce, Valeria

2018-05-09

Clinical and forensic toxicology can be defined as the two disciplines involved the detection, identification and measurement of xenobiotics in biological and non-biological specimens to help in the diagnosis, treatment, prognosis, prevention of poisonings and to disclose causes and contributory causes of fatal intoxications, respectively. This article explores the close connections between clinical and forensic toxicology in overlapping areas of interest. An update has been carried out of the following seven areas of interest in analytical toxicology: doping control, sudden cardiac death (SCD), brain death, sudden infant death syndrome (SIDS) and Munchausen syndrome by proxy (MSBP), prenatal exposure to drugs and fetal alcohol syndrome (FAS), drug-facilitated crimes (DFC) and intoxications by new psychoactive substances (NPS). While issues such as SCD, SIDS or doping control are investigated mainly in forensic laboratories, other as prenatal exposure to drugs or FAS are mainly treated in clinical laboratories. On the other hand, areas such MSBP, DFC or the intoxications by NPS are of interest in both laboratories. Some of these topics are initially treated in hospital emergency departments, involving clinical laboratories and sometimes lately derived to forensic laboratories. Conversely, cases with initial medical-legal implications and fatalities are directly handled by forensic toxicology, but may trigger further studies in the clinical setting. Many areas of common interest between clinical and forensic laboratories are building bridges between them. The increasing relationships are improving the growth, the reliability and the robustness of both kind of laboratories. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Editorial: Special issue on smart optical instruments and systems for space applications

Institute of Scientific and Technical Information of China (English)

XING; Fei

2015-01-01

Optical systems are playing more and more important roles for space applications,such as high accurate attitude determination and remote sensing systems etc.Innovations in optical systems have brought great advantages,some even revolutionary for the space applications.Accordingly,in this special issue of Smart Optical systems and instruments

Popper and Dingle on special relativity and the issue of symmetry

Science.gov (United States)

Dotson, Allen Clark

2012-02-01

Karl Popper and Herbert Dingle engaged in a fascinating debate concerning the kind of theory the special theory of relativity is. One of the issues was whether applications of the theory could be made consistent with the principle of relativity, a cornerstone of the theory itself. The principle of relativity seems to imply some sort of symmetry in results obtained for similar experiments as observed in two different inertial reference frames. Peter Hayes has recently dealt with the Dingle-Popper debate on this matter, as well as other issues. The present paper seeks to clarify what kind of symmetry is appropriate in a situation discussed by Popper, Dingle, and Hayes.

Introduction to the Special Issue on Marketing and Operations Management Interfaces and Coordination

OpenAIRE

Teck H. Ho; Christopher S. Tang

2004-01-01

This special issue, by addressing problems surrounding marketing and operations management, depicts state-of-the-art approaches, methodologies, and insights to improve a firm's or supply chain's overall performance. Top scholars in the field address many of the ways in which companies can synchronize their marketing and operations departments or their supply chain partners to improve competitiveness and profit. The information in this issue should be of interest both to academics and managers...

Ethical and scientific issues of nanotechnology in the workplace.

Science.gov (United States)

Schulte, Paul A; Salamanca-Buentello, Fabio

2007-01-01

In the absence of scientific clarity about the potential health effects of occupational exposure to nanoparticles, a need exists for guidance in decision making about hazards, risks, and controls. An identification of the ethical issues involved may be useful to decision makers, particularly employers, workers, investors, and health authorities. Because the goal of occupational safety and health is the prevention of disease in workers, the situations that have ethical implications that most affect workers have been identified. These situations include the a) identification and communication of hazards and risks by scientists, authorities, and employers; b) workers' acceptance of risk; c) selection and implementation of controls; d) establishment of medical screening programs; and e) investment in toxicologic and control research. The ethical issues involve the unbiased determination of hazards and risks, nonmaleficence (doing no harm), autonomy, justice, privacy, and promoting respect for persons. As the ethical issues are identified and explored, options for decision makers can be developed. Additionally, societal deliberations about workplace risks of nanotechnologies may be enhanced by special emphasis on small businesses and adoption of a global perspective.

Interpretation of postmortem forensic toxicology results for injury prevention research.

Science.gov (United States)

Drummer, Olaf H; Kennedy, Briohny; Bugeja, Lyndal; Ibrahim, Joseph Elias; Ozanne-Smith, Joan

2013-08-01

Forensic toxicological data provides valuable insight into the potential contribution of alcohol and drugs to external-cause deaths. There is a paucity of material that guides injury researchers on the principles that need to be considered when examining the presence and contribution of alcohol and drugs to these deaths. This paper aims to describe and discuss strengths and limitations of postmortem forensic toxicology sample selection, variations in analytical capabilities and data interpretation for injury prevention research. Issues to be considered by injury researchers include: the circumstances surrounding death (including the medical and drug use history of the deceased person); time and relevant historical factors; postmortem changes (including redistribution and instability); laboratory practices; specimens used; drug concentration; and attribution of contribution to death. This paper describes the range of considerations for testing and interpreting postmortem forensic toxicology, particularly when determining impairment or toxicity as possible causal factors in injury deaths. By describing these considerations, this paper has application to decisions about study design and case inclusion in injury prevention research, and to the interpretation of research findings.

Research, Learning Theory, and the Ideas of Robert G. Sidnell. Special Issue.

Science.gov (United States)

Alexander, David, Ed.; And Others

1987-01-01

Intended as a memorial to Robert G. Sidnell, this special issue contains articles about areas of music education which he promoted. In "The Dimensions of Research in Music Education," Sidnell concluded that music education research encompasses all humanistic disciplines as well as the behavioral and social sciences. James Carlsen, in…

Occupational medicine and toxicology

Directory of Open Access Journals (Sweden)

Fischer Axel

2006-02-01

Full Text Available Abstract This editorial is to announce the Journal of Occupational Medicine and Toxicology, a new Open Access, peer-reviewed, online journal published by BioMed Central. Occupational medicine and toxicology belong to the most wide ranging disciplines of all medical specialties. The field is devoted to the diagnosis, prevention, management and scientific analysis of diseases from the fields of occupational and environmental medicine and toxicology. It also covers the promotion of occupational and environmental health. The complexity of modern industrial processes has dramatically changed over the past years and today's areas include effects of atmospheric pollution, carcinogenesis, biological monitoring, ergonomics, epidemiology, product safety and health promotion. We hope that the launch of the Journal of Occupational Medicine and Toxicology will aid in the advance of these important areas of research bringing together multi-disciplinary research findings.

Legislation for the countermeasures on special issues of nuclear safety regulations

International Nuclear Information System (INIS)

Cho, Byung Sun; Lee, Mo Sung; Chung, Gum Chun; Kim, Heon Jin; Oh, Ho Chul

2004-02-01

Since the present nuclear safety regulation has some legal problems that refer to special issues and contents of regulatory provisions, this report has preformed research on the legal basic theory of nuclear safety regulation to solve the problems. In addition, this report analyzed the problems of each provisions and suggested the revision drafts on the basis of analyzing problems and the undergoing theory of nuclear safety regulation

Legislation for the countermeasures on special issues of nuclear safety regulations

Energy Technology Data Exchange (ETDEWEB)

Cho, Byung Sun; Lee, Mo Sung; Chung, Gum Chun; Kim, Heon Jin; Oh, Ho Chul [Chongju Univ., Cheongju (Korea, Republic of)

2004-02-15

Since the present nuclear safety regulation has some legal problems that refer to special issues and contents of regulatory provisions, this report has preformed research on the legal basic theory of nuclear safety regulation to solve the problems. In addition, this report analyzed the problems of each provisions and suggested the revision drafts on the basis of analyzing problems and the undergoing theory of nuclear safety regulation.

Agenda of behavioral toxicology

Energy Technology Data Exchange (ETDEWEB)

Weiss, B

1978-01-01

The author describes behavioral toxicology as a new discipline and contrasts it to the fields of physics and pharmacology. Several questions are raised and discussed concerning the field of behavioral toxicology. Some of these questions are: (1) how is an adverse behavioral effect recognized; (2) how can the non-specific be specified; (3) are standardized test batteries feasible. The problem of chronic intake is discussed as well as drawing information from other related disciplines such as neurochemistry, neuropathology and neurophysiology. The author concludes with several statements concerning new directions in the discipline of behavioral toxicology.

Special Issue on Automatic Application Tuning for HPC Architectures

Directory of Open Access Journals (Sweden)

Siegfried Benkner

2014-01-01

Full Text Available High Performance Computing architectures have become incredibly complex and exploiting their full potential is becoming more and more challenging. As a consequence, automatic performance tuning (autotuning of HPC applications is of growing interest and many research groups around the world are currently involved. Autotuning is still a rapidly evolving research field with many different approaches being taken. This special issue features selected papers presented at the Dagstuhl seminar on “Automatic Application Tuning for HPC Architectures” in October 2013, which brought together researchers from the areas of autotuning and performance analysis in order to exchange ideas and steer future collaborations.

Editorial: Introduction to the Special Issue ;Slope Tectonics: Inherited Structures, Morphology of Deformation and Catastrophic Failure;

Science.gov (United States)

Hermanns, R. L.; Oppikofer, T.; Jaboyedoff, M.; Clague, J. J.; Scarascia-Mugnozza, G.

2017-07-01

The "Conference on Slope Tectonics" has become an international scientific meeting point to present and discuss a variety of topics related to slope deformation and the deposits of related failures. The first conference took place on February 15-16, 2008 at University of Lausanne (Switzerland). It was followed by a second conference on September 6-10, 2011, in Austria (organized by the Geological Survey of Austria) and a third on September 8-12, 2014, in Norway (organized by the Geological Survey of Norway). The two later events included field trips. It has become a tradition that selected papers from these conference are published - papers from the first conference were published by the Geological Society as Special Publication 351 (Jaboyedoff, 2011), and those from the second conference were published in a special issue of Tectonophysics (Baron and Jaboyedoff, 2013). This special issue of Geomorphology is a collection of papers presented at the Norwegian Conference on Slope Tectonics. This collection of papers focuses on the role of tectonics in gravitationally induced rock-slope instabilities. The slopes either deform over long periods as deep-seated gravitational slope deformation (DSGSD) or more rapidly as rockslides or rock avalanches. The reconstruction of slope deformation is an integral part of the studies captured in this special issue.

Towards Equitable and Sustainable Urban Space: Introduction to Special Issue on “Urban Land and Sustainable Development”

Directory of Open Access Journals (Sweden)

Yehua Dennis Wei

2016-08-01

Full Text Available The unprecedented wave of global urbanization has exerted increased pressure on urban land and made land-use sustainability an urgent concern. This Special Issue examines patterns, structures, and dynamics of urban land use from the economic, social, and, to a lesser extent, environmental standpoints, in light of the goal of equitable and sustainable development. This introduction discusses the background and design of the Special Issue and highlights the contribution of the selected papers.

Special issue on compact x-ray sources

Science.gov (United States)

Hooker, Simon; Midorikawa, Katsumi; Rosenzweig, James

2014-04-01

Journal of Physics B: Atomic, Molecular and Optical Physics is delighted to announce a forthcoming special issue on compact x-ray sources, to appear in the winter of 2014, and invites you to submit a paper. The potential for high-brilliance x- and gamma-ray sources driven by advanced, compact accelerators has gained increasing attention in recent years. These novel sources—sometimes dubbed 'fifth generation sources'—will build on the revolutionary advance of the x-ray free-electron laser (FEL). New radiation sources of this type have widespread applications, including in ultra-fast imaging, diagnostic and therapeutic medicine, and studies of matter under extreme conditions. Rapid advances in compact accelerators and in FEL techniques make this an opportune moment to consider the opportunities which could be realized by bringing these two fields together. Further, the successful development of compact radiation sources driven by compact accelerators will be a significant milestone on the road to the development of high-gradient colliders able to operate at the frontiers of particle physics. Thus the time is right to publish a peer-reviewed collection of contributions concerning the state-of-the-art in: advanced and novel acceleration techniques; sophisticated physics at the frontier of FELs; and the underlying and enabling techniques of high brightness electron beam physics. Interdisciplinary research connecting two or more of these fields is also increasingly represented, as exemplified by entirely new concepts such as plasma based electron beam sources, and coherent imaging with fs-class electron beams. We hope that in producing this special edition of Journal of Physics B: Atomic, Molecular and Optical Physics (iopscience.iop.org/0953-4075/) we may help further a challenging mission and ongoing intellectual adventure: the harnessing of newly emergent, compact advanced accelerators to the creation of new, agile light sources with unprecedented capabilities

A practice analysis of toxicology.

Science.gov (United States)

Wood, Carol S; Weis, Christopher P; Caro, Carla M; Roe, Amy

2016-12-01

In 2015, the American Board of Toxicology (ABT), with collaboration from the Society of Toxicology (SOT), in consultation with Professional Examination Service, performed a practice analysis study of the knowledge required for general toxicology. The purpose of this study is to help assure that the examination and requirements for attainment of Diplomate status are relevant to modern toxicology and based upon an empirical foundation of knowledge. A profile of the domains and tasks used in toxicology practice was developed by subject-matter experts representing a broad range of experiences and perspectives. An on-line survey of toxicologists, including Diplomates of the ABT and SOT members, confirmed the delineation. Results of the study can be used to improve understanding of toxicology practice, to better serve all toxicologists, and to present the role of toxicologists to those outside the profession. Survey results may also be used by the ABT Board of Directors to develop test specifications for the certifying examination and will be useful for evaluating and updating the content of professional preparation, development, and continuing education programs. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

Toward a Sustainable Low-Carbon China: A Review of the Special Issue of “Energy Economics and Management”

Directory of Open Access Journals (Sweden)

Ning Zhang

2016-08-01

Full Text Available Severe environmental quality deterioration, along with predatory exploitation of energy resources, are generally associated with economic growth, especially in China. Against this background, the 6th Annual Conference of Energy Economics and Management provides a platform for examining outperforming governance factors and mechanisms of energy economics and policy. Thanks to Sustainability for providing this special issue. This editorial highlights the contents and methodologies of the special issue for this conference, presenting diverse issues in energy economics and management. We also suggest guidelines for future study in energy economics and management.

Resolution of aviation forensic toxicology findings with the aid of DNA profiling.

Science.gov (United States)

Chaturvedi, Arvind K; Craft, Kristi J; Kupfer, Doris M; Burian, Dennis; Canfield, Dennis V

2011-03-20

Body components of aviation accident fatalities are often scattered, disintegrated, commingled, contaminated, and/or putrefied at accident scenes. These situations may impose difficulties in victim identification/tissue matching. The prevalence of misidentification in relation to aviation accident forensic toxicology has not been well established. Therefore, the Civil Aerospace Medical Institute (CAMI) toxicology database was searched for the 1998-2008 period for those cases wherein DNA profiling was performed to resolve identity issue of the samples submitted to CAMI for toxicological evaluation. During this period, biological samples from the casualties of a total of 3523 accidents were submitted to CAMI. The submitted samples were primarily from pilots. Out of the 3523 accidents, at least, one fatality had occurred in 3366 (≈ 96%) accidents; thus, these accidents were considered fatal accidents. Accordingly, biological samples from 3319 pilots (3319 of the 3366 accidents) were received at CAMI for toxicological testing. Of these 3319 pilots, 3275 (≈ 99%) were fatally injured. DNA profiling was performed in 15 (≈ 0.5%) of the 3319 accidents. The profiling was conducted upon the requests of families in two accidents, accident investigators in three, and pathologists in four. In six accidents, contradictory toxicological findings led CAMI to initiate DNA profiling. The requests made by families and investigators were primarily triggered by inconsistency between the toxicological results and the history of drug use of the victims, while by pathologists because of commingling of samples. In three (20%) of the 15 accidents, at least one submitted sample was misidentified or mislabeled. The present study demonstrated that the number of aviation accident cases requiring DNA profiling was small and this DNA approach was effectively applied in resolving aviation toxicology findings associated with those accidents. Published by Elsevier Ireland Ltd.

High Throughput Transcriptomics @ USEPA (Toxicology ...

Science.gov (United States)

The ideal chemical testing approach will provide complete coverage of all relevant toxicological responses. It should be sensitive and specific It should identify the mechanism/mode-of-action (with dose-dependence). It should identify responses relevant to the species of interest. Responses should ideally be translated into tissue-, organ-, and organism-level effects. It must be economical and scalable. Using a High Throughput Transcriptomics platform within US EPA provides broader coverage of biological activity space and toxicological MOAs and helps fill the toxicological data gap. Slide presentation at the 2016 ToxForum on using High Throughput Transcriptomics at US EPA for broader coverage biological activity space and toxicological MOAs.

The impacts and acceptance of agricultural biotechnology: an introduction to the special issue

NARCIS (Netherlands)

Zilberman, D.; Wesseler, J.H.H.

2014-01-01

Attitudes towards and acceptance of agricultural biotechnology, which involves inserting genes that carry new traits into existing varieties, has been subject to much debate. This special issue aims to address several gaps in the literature on genetically modified (GM) technology in agriculture.

Summary introduction to environmental toxicology

International Nuclear Information System (INIS)

Heinzow, B.; Jessen, H.; Wendorff, D.

1986-01-01

The increasing environmental consciousness and the increasing public interest in environmental medicine and toxicology is much appreciated by the Research Institute for Environmental Toxicology. This information brochure gives the reader some insight into the importance of environmental toxicology and into the waste of the Research Institute. In response to the current situation, the authors have included an appendix on radiation protection. (orig./PW) [de

The Emergence of Systematic Review in Toxicology.

Science.gov (United States)

Stephens, Martin L; Betts, Kellyn; Beck, Nancy B; Cogliano, Vincent; Dickersin, Kay; Fitzpatrick, Suzanne; Freeman, James; Gray, George; Hartung, Thomas; McPartland, Jennifer; Rooney, Andrew A; Scherer, Roberta W; Verloo, Didier; Hoffmann, Sebastian

2016-07-01

The Evidence-based Toxicology Collaboration hosted a workshop on "The Emergence of Systematic Review and Related Evidence-based Approaches in Toxicology," on November 21, 2014 in Baltimore, Maryland. The workshop featured speakers from agencies and organizations applying systematic review approaches to questions in toxicology, speakers with experience in conducting systematic reviews in medicine and healthcare, and stakeholders in industry, government, academia, and non-governmental organizations. Based on the workshop presentations and discussion, here we address the state of systematic review methods in toxicology, historical antecedents in both medicine and toxicology, challenges to the translation of systematic review from medicine to toxicology, and thoughts on the way forward. We conclude with a recommendation that as various agencies and organizations adapt systematic review methods, they continue to work together to ensure that there is a harmonized process for how the basic elements of systematic review methods are applied in toxicology. © The Author 2016. Published by Oxford University Press on behalf of the Society of Toxicology.

Toxicology: a discipline in need of academic anchoring--the point of view of the German Society of Toxicology.

Science.gov (United States)

Gundert-Remy, U; Barth, H; Bürkle, A; Degen, G H; Landsiedel, R

2015-10-01

The paper describes the importance of toxicology as a discipline, its past achievements, current scientific challenges, and future development. Toxicological expertise is instrumental in the reduction of human health risks arising from chemicals and drugs. Toxicological assessment is needed to evaluate evidence and arguments, whether or not there is a scientific base for concern. The immense success already achieved by toxicological work is exemplified by reduced pollution of air, soil, water, and safer working places. Predominantly predictive toxicological testing is derived from the findings to assess risks to humans and the environment. Assessment of the adversity of molecular effects (including epigenetic effects), the effects of mixtures, and integration of exposure and biokinetics into in vitro testing are emerging challenges for toxicology. Toxicology is a translational science with its base in fundamental science. Academic institutions play an essential part by providing scientific innovation and education of young scientists.

Aspects of matrix effects in applications of liquid chromatography-mass spectrometry to forensic and clinical toxicology--a review.

Science.gov (United States)

Peters, Frank T; Remane, Daniela

2012-06-01

In the last decade, liquid chromatography coupled to (tandem) mass spectrometry (LC-MS(-MS)) has become a versatile technique with many routine applications in clinical and forensic toxicology. However, it is well-known that ionization in LC-MS(-MS) is prone to so-called matrix effects, i.e., alteration in response due to the presence of co-eluting compounds that may increase (ion enhancement) or reduce (ion suppression) ionization of the analyte. Since the first reports on such matrix effects, numerous papers have been published on this matter and the subject has been reviewed several times. However, none of the existing reviews has specifically addressed aspects of matrix effects of particular interest and relevance to clinical and forensic toxicology, for example matrix effects in methods for multi-analyte or systematic toxicological analysis or matrix effects in (alternative) matrices almost exclusively analyzed in clinical and forensic toxicology, for example meconium, hair, oral fluid, or decomposed samples in postmortem toxicology. This review article will therefore focus on these issues, critically discussing experiments and results of matrix effects in LC-MS(-MS) applications in clinical and forensic toxicology. Moreover, it provides guidance on performance of studies on matrix effects in LC-MS(-MS) procedures in systematic toxicological analysis and postmortem toxicology.

Review of the French environmental nuclear toxicology programme

International Nuclear Information System (INIS)

Leguay, J.J.; Menager, M.T.; Ansoborlo, E.

2005-01-01

Full text of publication follows: The fate of radionuclides in the geosphere and in particular their transfer in the biosphere constitutes an essential key point in relation with environmental issues as well as their effects on living organisms. In order to answer to such issues, an Environmental Nuclear Toxicology Programme (a French national programme) has been launched in 2001 for a period of 5 years. It is a resolutely forward-looking programme gathering all the main research institutes (CEA, CNRS, Inserm and Inra) and comprising 15 projects that pool the expertise of physicians, biologists, chemists, physicists... The programme's central thrust is the study of the biological effects of nuclear toxics, i.e., most part of the compounds encountered in the nuclear industry ( 3 H, Co, Cd, Se, Sr, Tc, I, Cs, Pb U, Pu) that may have a chemical and (or) radiological toxicity towards living organisms. Its objectives are to study the toxicology of the materials used, in particular in nuclear fuels, to analyse the biological effects of radionuclides (naturally-occurring or artificial) that may be present in the environment, and to examine the effects of chemically toxic metals, particularly the heavy metals, used in nuclear and medical research and industrial activities. For the radionuclides, the aim is to determine the potential health consequences of exposure to these materials and to make realistic estimates of exposure to the corresponding risks incurred. The main research topics concern three types of mechanisms in bacteria, plants and animals: - Mechanisms by which elements are transferred and transported from cell to cell; - Mechanisms by which toxics accumulate in cell compartment and organs; - Specific detoxification mechanisms. In all cases, special emphasis is placed on work that makes possible to compare the toxicity of different elements relative to a better known toxic chemical, such as cadmium or cobalt, and also, for as many elements as possible, work to

Putting Emotion into the Self: A Response to the 2008 "Journal of Moral Education" Special Issue on Moral Functioning

Science.gov (United States)

Kristjansson, Kristjan

2009-01-01

This paper takes as its starting point the Journal of Moral Education Special Issue (September, 2008, 37[3]) "Towards an integrated model of moral reasoning". Although explicitly post-Kohlbergian, the authors in this Special Issue do not, I argue, depart far enough from Kohlberg's impoverished notion of the role of the affective in moral life--or…

Special issue photovoltaic

International Nuclear Information System (INIS)

2004-01-01

In this letter of the INES (french National Institute of the Solar Energy), a special interest is given to photovoltaic realizations in Europe. Many information are provided on different topics: the China future fifth world producer of cells in 2005, batteries and hydrogen to storage the solar energy and a technical sheet on a photovoltaic autonomous site installation for electric power production. (A.L.B.)

History of Japanese Society of Toxicology.

Science.gov (United States)

Satoh, Tetsuo

2016-01-01

Founded in 1981, the Japanese Society of Toxicology (JSOT) has grown into an organization of nearly 3,000 members working together to advance the nation's scientific knowledge and understanding of toxicology through the implementation of planning that ensures a systematic and efficient expenditure of energies and resources, and is closely aligned with a strategy for accomplishing the Society's long-range plans. To promote public education in toxicology, the Society organizes public lectures during each year's annual meeting. Other activities include hosting scientific conferences, promoting continuing education, and facilitating international collaboration. Internally, the JSOT operates five standing committees: General Affairs, Educational, Editorial, Finance, and Science and Publicity to handle its necessary relationships. To bestow official recognition, the Society established its Toxicologist Certification Program in 1997, and has certified 536 members as Diplomat Toxicologists (DJSOT) as of May 1, 2016. Furthermore, on the same date, 43 JSOT members were certified as Emeritus Diplomats of the JSOT (EDJSOT). The Society has launched two official journals, the "Journal of Toxicological Sciences (JTS)" in 1981 and "Fundamental Toxicological Sciences (Fundam. Toxicol. Sci.)" in 2014. As for participation in the international organizations, the JSOT (then known as the Toxicological Research Group) joined the International Union of Toxicology as a charter member in 1980, and became a founding member of the Asian Society of Toxicology at its inauguration in 1994. Into the future, the JSOT will continue working diligently to advance knowledge and understanding of toxicology and secure its place among the interdisciplinary fields of science, humane studies, and ethics.

Psychosocial Studies of Migration and Community: Introduction to the Special Issue

Directory of Open Access Journals (Sweden)

Douglas D. Perkins

2011-11-01

Full Text Available Introducing the special issue on psychosocial studies of migration and community, we briefly reflect on the global increase in, and issues related to, both international and domestic migration, particularly from rural areas of less developed countries, which has fueled rapid urbanization and intercultural tensions in both post-industrial and developing countries. Topics covered in the issue are summarized, including an Italian study of the emotional impact of discrimination against immigrant adolescents; acculturation, integration and adaptation of Muslim immigrant youth in New Zealand; perceptions of human trafficking in Moldova; Chinese migrant workers´ social networks, life satisfaction and political participation; physician brain drain from sub-Saharan Africa; and a critical analysis of the oppressive and liberating impact of organizations on immigrants, multiculturalism, and social justice. The issue concludes with commentary articles by four leading international scholars of migration and community. The breadth of topics helps to address wide-ranging gaps in the literature, but more psychological and social research must connect ecologically across multiple levels and to cultural, political, economic, and environmental studies of migration and community.

Animal-free toxicology

DEFF Research Database (Denmark)

Knudsen, Lisbeth E

2013-01-01

Human data on exposure and adverse effects are the most appropriate for human risk assessment, and modern toxicology focuses on human pathway analysis and the development of human biomarkers. Human biomonitoring and human placental transport studies provide necessary information for human risk...... assessment, in accordance with the legislation on chemical, medicine and food safety. Toxicology studies based on human mechanistic and exposure information can replace animal studies. These animal-free approaches can be further supplemented by new in silico methods and chemical structure......-activity relationships. The inclusion of replacement expertise in the international Three Rs centres, the ongoing exploration of alternatives to animal research, and the improvement of conditions for research animals, all imply the beginning of a paradigm shift in toxicology research toward the use of human data....

42 CFR 493.1213 - Condition: Toxicology.

Science.gov (United States)

2010-10-01

... 42 Public Health 5 2010-10-01 2010-10-01 false Condition: Toxicology. 493.1213 Section 493.1213 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES....1213 Condition: Toxicology. If the laboratory provides services in the subspecialty of Toxicology, the...

Special Issue: 14th International Symposium on Novel and Nano Materials

Science.gov (United States)

Kim, Woo-Byoung; Choa, Yong-Ho; Ahn, Hyo-Jin; Park, Il-Kyu

2017-09-01

This Special Issue of Applied Surface Science is intended to provide a collection of peer-reviewed contributions presented at the 14th International Symposium on Novel Nano Materials (ISNNM) held in Budapest, Hungary as one of the most beautiful cities in Europe from July 3 to July 8, 2016. All selected papers underwent the regular peer review process as set by the journal of Applied Surface Science and its publisher (Elsevier).

Special cluster issue on tribocorrosion of dental materials

Science.gov (United States)

Mathew, Mathew T.; Stack, Margaret M.

2013-10-01

Tribocorrosion affects all walks of life from oil and gas conversion to biomedical materials. Wear can interact with corrosion to enhance it or impede it; conversely, corrosion can enhance or impede wear. The understanding of the interactions between physical and chemical phenomena has been greatly assisted by electrochemical and microscopic techniques. In dentistry, it is well recognized that erosion due to dissolution (a term physicists use to denote wear) of enamel can result in tooth decay; however, the effects of the oral environment, i.e. pH levels, electrochemical potential and any interactions due to the forces involved in chewing are not well understood. This special cluster issue includes investigations on the fundamentals of wear-corrosion interactions involved in simulated oral environments, including candidate dental implant and veneer materials. The issue commences with a fundamental study of titanium implants and this is followed by an analysis of the behaviour of commonly used temporomandibular devices in a synovial fluid-like environment. The analysis of tribocorrosion mechanisms of Ti6Al4V biomedical alloys in artificial saliva with different pHs is addressed and is followed by a paper on fretting wear, on hydroxyapatite-titanium composites in simulated body fluid, supplemented with protein (bovine serum albumin). The effects of acid treatments on tooth enamel, and as a surface engineering technique for dental implants, are investigated in two further contributions. An analysis of the physiological parameters of intraoral wear is addressed; this is followed by a study of candidate dental materials in common beverages such as tea and coffee with varying acidity and viscosity and the use of wear maps to identify the safety zones for prediction of material degradation in such conditions. Hence, the special cluster issue consists of a range of tribocorrosion contributions involving many aspects of dental tribocorrosion, from analysis of physiological

Preface to special issue of selected papers from Theoretical, Experimental, and Computational Mechanics (TECM)

DEFF Research Database (Denmark)

Jabbari, Masoud; Sarlak Chivaee, Hamid; Hattel, Jesper Henri

2017-01-01

We are pleased to introduce this special issue of the Applied Mathematical Modelling journal with highlights from theTheoretical, Experimental, and Computational Mechanics Symposium (TECM-2015). This special issue consists of four rigorouslyselected papers originally presented at TECM-2015...... as a part of the 13th International Conference of Numerical Analysisand Applied Mathematics 2015 (ICNAAM 2015), which was held on 23-29 September 2015 in Rhodes, Greece.The symposium attracted a broad range of international and local leaders in theoretical, experimental, and computational mechanics across...... various fields and application. The symposium did an excellent job of outlining the current landscape of computational mechanics and its capabilities in solving complex industrial problems in the process industries, and we agree with the editor-in-chief of the journal that it is certainly worthwhile...

Introduction to the special issue: Observed and projected changes in weather and climate extremes

Directory of Open Access Journals (Sweden)

John E. Hay

2016-03-01

Full Text Available This Special Issue documents not only the more recent progress made in detecting and attributing changes in temperature and precipitation extremes in the observational record, but also in projecting changes in such extremes at regional and local scales. It also deals with the impacts and other consequences and implications of both the historic and anticipated changes in extreme weather and climate events. Impact assessments using both dynamical downscaling and statistical modelling for two tropical cyclones are reported, as well as for storm surge and extreme wave changes. The Special Issue concludes with a consideration of some policy implications and practical applications arising from our relatively robust understanding of how the build up of greenhouse gases in the Earth’s atmosphere affects weather and climate extremes.

Virtual Reality and Its Potential Use in Special Education. Identifying Emerging Issues and Trends in Technology for Special Education.

Science.gov (United States)

Woodward, John

As part of a 3-year study to identify emerging issues and trends in technology for special education, this paper addresses the possible contributions of virtual reality technology to educational services for students with disabilities. An example of the use of virtual reality in medical imaging introduces the paper and leads to a brief review of…

Special issue “International Geomagnetic Reference Field—the twelfth generation”

OpenAIRE

Thébault, E.; Finlay, C. C.; Toh, H.

2015-01-01

This special issue of Earth, Planets and Space, synthesizes the efforts made during the construction of the twelfth generation of the International Geomagnetic Reference Field (IGRF-12) that was released online in December 2014 (http://www.ngdc.noaa.gov/IAGA/vmod/ igrf.html). The IGRF-12 is a series of standard mathematical models describing the large scale internal part of the Earth’s magnetic field between epochs 1900.0 and 2015.0 with a forecast to epoch 2020.0. This activity has been main...

Special Issue: Software-engineering, Properites of Language and Aspect Technologies

DEFF Research Database (Denmark)

Bergmans, Lodewijk; Gybels, Kris; Ernst, Erik

2008-01-01

, comprehensibility and evolvability. As (aspect) languages are being pushed to meet their boundaries and limitations, the trade-offs in language design become increasingly difficult to make. In particular, a trade-off may be perfectly sensible in one application context, but much less so in another. In this special...... issue you will find three full papers, originating from the SPLAT workshop series, that address this last issue. Each of these papers resolves a fundamental language design trade-off by offering a language mechanism that lifts the design decisions to the application programmers: The first paper, "User......-Defined Join Point Selectors-An Extension Mechanism for Pointcut Languages" by Breuel and Reverbel, addresses the fact that aspect programmers are pushing the boundaries of pointcut languages. As a result, aspect language designers have to make a trade-off between limited expressiveness of traditional types...

Research Article Special Issue

African Journals Online (AJOL)

2016-05-15

May 15, 2016 ... Near-fault earthquake issue is almost a new issue in earthquake engineering. ... although those countries had advanced regulations for seismic design of ... allocating the plastic joints according to development guideline and ...

“Introduction to Coolabah special issue on placescape, placemaking, placemarking, placedness … geography and cultural production”

Directory of Open Access Journals (Sweden)

Bill Boyd

2013-10-01

Full Text Available This special issue of the journal Coolabah comprises contributed papers that examine the relationships between place, placescape and landscape – Australian places and imaginings. Australian perspectives of place and cultural production unavoidably confront issues of identity simultaneously from antipodean and elsewhere vantage points.

The Global Educational Toxicology Uniting Project (GETUP): an Analysis of the First Year of a Novel Toxicology Education Project.

Science.gov (United States)

Wong, Anselm; Vohra, Rais; Ruha, Anne-Michelle; Koutsogiannis, Zeff; Graeme, Kimberlie; Dargan, Paul I; Wood, David M; Greene, Shaun L

2015-09-01

The international boundaries to medical education are becoming less marked as new technologies such as multiuser videoconferencing are developed and become more accessible to help bridge the communication gaps. The Global Educational Toxicology Uniting Project (GETUP) is aimed at connecting clinicians in countries with established clinical toxicology services to clinicians in countries without clinical toxicologists around the globe. Centers that manage or consult on toxicology cases were registered through the American College of Medical Toxicology website via Survey Monkey®. Data was analyzed retrospectively from February 2014 to January 2015. Google hangouts® was used as the main conferencing software, but some sites preferred the use of Skype®. Registration data included contact details and toxicology background and qualifications. Thirty sites in 19 different countries in Australasia, Europe, Africa, and America were registered. Twenty-eight (93 %) sites were located in a major urban center, one (3.5 %) site in a major rural center and one (3.5 %) a private practice. Expectations of GETUP included sharing toxicology cases and education (30, 100 % of sites), assistance with toxicology management guidelines (2, 7 %), assistance with providing a toxicology teaching curriculum in languages other than English (2, 7 %), and managing toxicology presentations in resource-poor settings, international collaboration, and toxicovigilance (2 sites, 7 %). Twenty-two conferences were performed during the first 12 months with a mean of 3 cases per conference. GETUP has connected countries and clinical units with and without toxicology services and will provide a platform to improve international collaboration in clinical toxicology.

Disaster Mental Health and Positive Psychology-Considering the Context of Natural and Technological Disasters: An Introduction to the Special Issue.

Science.gov (United States)

Schulenberg, Stefan E

2016-12-01

This article serves as an introduction to the Journal of Clinical Psychology's special issue on disaster mental health and positive psychology. The special issue comprises two sections. The first section presents a series of data-driven articles and research-informed reviews examining meaning and resilience in the context of natural and technological disasters. The second section presents key topics in the area of disaster mental health, with particular relevance for positive psychology and related frameworks. The special issue is intended to bridge the gap between these two areas of applied science, with the audience being experienced clinicians or clinicians in training. © 2016 Wiley Periodicals, Inc.

Special Issue “Actuarial and Financial Risks in Life Insurance, Pensions and Household Finance”

Directory of Open Access Journals (Sweden)

Luca Regis

2017-12-01

Full Text Available The aim of the Special Issue is to address some of the main challenges individuals and companies face in managing financial and actuarial risks, when dealing with their investment/retirement or business-related decisions [...

Special Issue: New trends and applications on hybrid artificial intelligence systems

OpenAIRE

Corchado Rodríguez, Emilio; Graña Romay, Manuel; Woźniak, MichaŁ

2017-01-01

This Special Issue is an outgrowth of the HAIS'10, the 5th International Conference on Hybrid Artificial Intelligence Systems, which was held in San Sebastián, Spain, 23–25 June 2010. The HAIS conference series is devoted to the presentation of innovative techniques involving the hybridization of emerging and active topics in data mining and decision support systems, information fusion, evolutionary computation, visualization techniques, ensemble models, intelligent agent-based systems (compl...

KFK Institute of Genetics and of Toxicology of Fission Materials. 1990 annual report on research and development work

International Nuclear Information System (INIS)

1991-03-01

The annual report summarizes the R+D activities of the Institute performed in the year 1990 in accordance with the Institute's R+D framework. The activities cover studies on gene repair, gene regulation, biological carcinogenesis, molecular genetics of enkaryontic genes, genetic mouse models for the study of human disease, radiotoxicology of the actinides, cellular inhalation toxicology, cellular and molecular toxicology, fractionation and speciation of actinides in vivo. There is a bibliography of publications issued by members of the Institute in 1990 and of the IGT primary reports issued in 1989 and 1990, and a list of lectures held but not available in printed form. (VHE) [de

Introduction to the Special Issue on Specification Analysis and Verification of Reactive Systems

NARCIS (Netherlands)

Delzanno, Giorgio; Etalle, Sandro; Gabbrielli, Maurizio

2006-01-01

This special issue is inspired by the homonymous ICLP workshops that took place during ICLP 2001 and ICLP 2002. Extending and shifting slightly from the scope of their predecessors (on verification and logic languages) held in the context of previous editions of ICLP, the aim of the SAVE workshops

Preface [Special issue on dataTEL – Data Supported Research in Technology-Enhanced Learning

NARCIS (Netherlands)

Drachsler, Hendrik; Verbert, Katrien; Manouselis, Nikos; Vuorikari, Riina; Wolpers, Martin; Lindstaedt, Stefanie

2012-01-01

Drachsler, H., Verbert, K., Manouselis, N., Vuorikari, R., Wolpers, M., & Lindstaedt, S. (2012). Preface [Special issue on dataTEL – Data Supported Research in Technology-Enhanced Learning]. International Journal Technology Enhanced Learning, Vol. 4, Nos. 1/2, 2012.

Astrophysical implications of extraterrestrial materials: A special issue for Ernst K. Zinner

Science.gov (United States)

Nittler, Larry R.

2018-01-01

This special issue is dedicated to the memory of Dr. Ernst K. Zinner (Fig. 1). Dr. Zinner (1937-2015) was a pioneer in the use of Secondary Ion Mass Spectrometry (SIMS) in geo- and cosmochemistry. His contributions to science were vast, but in addition to his foundational SIMS development work, he is best known for the discovery and detailed characterization of presolar stardust grains in meteorites. This discovery opened up important new connections between astrophysics and meteoritical research and this is the overarching theme of this issue. Throughout his career, Ernst was a teacher, mentor, friend, and generous collaborator to legions of scientists. This issue presents research by many who were taught by, inspired by, and/or collaborated with this innovative cosmochemist and astrophysicist. In addition to the author, Ernst's former students and collaborators Drs. Christine Floss (Washington University) Peter Hoppe (MPI for chemistry, Mainz, Germany), and Kevin McKeegan (University of California, Los Angeles) served as Guest Editors for this issue.

Preface of the Special Issue: “Recent CMV Research”

Directory of Open Access Journals (Sweden)

Kayla Dufrene

2014-01-01

Full Text Available This Viruses Special Issue on Recent Cytomegalovirus (CMV Research is dedicated to the patients who have suffered CMV infection and to their parents, families and caregivers. We are including as a Preface to this issue the insights of a young college student, Kayla Dufrene, who suffered congenital CMV infection and contacted me and Dr. Roberta DeBiasi, to interview us to learn more about CMV. As I was just returning to the DC area from the 4th Congenital CMV Conference in San Francisco, I was particularly receptive to her request. When we met Kayla, we were both impressed with her personal strength and ability to cope with her disabilities and needed medical treatments. Despite it all, Kayla has an exceptionally positive outlook on life, feeling even lucky. She has not only coped, but has transcended her difficulties. I am proud to say that she was on the Dean’s List (Figure 1 at Gallaudet University. Ultimately, her hope lies in our fields’ efforts to develop a vaccine to prevent CMV disease in other children.

EDITORIAL: Special issue featuring articles arising from the 11th High-Tech Plasma Processes Conference Special issue featuring articles arising from the 11th High-Tech Plasma Processes Conference

Science.gov (United States)

Bruggeman, Peter; Degrez, Gérard; Delplancke, Marie-Paule; Gleizes, Alain

2011-05-01

The 11th High-Tech Plasma Processes Conference (HTPP) was held in Brussels, Belgium, 27 June-2 July, 2010. HTPP started as a thermal plasma conference and gradually expanded to include low-temperature plasmas. The conference was founded by Jacques Amouroux and Pierre Fauchais, and aims to bring together different scientific communities to facilitate contacts between science, technology and industry, providing a platform for the exploration of elementary processes and applications in and by plasmas. The first HTPP was held in Odeillo, France, in 1990. Since then it has been held every other year in different European cities: Paris, Aachen, Athens, Strasbourg, Saint-Petersburg, Patras and Brussels. The 11th HTPP conference was attended by 125 participants from 19 countries. The program involved 14 invited talks, 34 contributed talks, 72 posters and a software demonstration and hands-on session for plasma modelling. The 12th HTPP conference will be held 24-28 June 2012, in Bologna, Italy. A larger part of the contributions to the 11th HTPP has been published in the Journal of Physics: Conference Series (JPCS) volume 275, 2011. All invited speakers and other contributors, as selected by the Steering, Scientific and Organizing Committee, were invited to submit a paper based on their contributions for this special issue which is peer reviewed by the journal. Both this special issue and the JPCS volume aim to bring the 11th HTPP to a wider audience. The publications are a nice example of the broad topic range of the conference. The JPCS volume contains papers covering fundamental aspects on radiative processes of thermal plasmas, modelling of thermal arcs and non-thermal RF plasma jets, plasma diagnostics including flow and heat flux measurements of thermal plasmas, radical density measurements and laser-induced breakdown spectroscopy. The applications-oriented contributions of the JPCS volume include plasma spraying, synthesis of (nano-sized) materials, surface

Research Article Special Issue

African Journals Online (AJOL)

pc

2017-10-17

Oct 17, 2017 ... delivery system which are primary care, secondary care, tertiary care, ..... services are usually delivered by nurse practitioners, medical assistants, ... The quaternary care is a highly specialized care with a target to cure.

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2016-07-16

Jul 16, 2016 ... In this research, two questionnaires of knowledge management and employees' ... development, human resources are the most important tool and capital of ... foster talent, to improve public and specialized awareness, and to ...

Research Article Special Issue

African Journals Online (AJOL)

pc

2018-05-01

May 1, 2018 ... quantitative method used, data analysis and findings of Telehealth ... The users' acceptance of wireless sensor devise (Motes) for ..... access to specialized health care: the Telehealth Network of Minas Gerais, Brazil. Bulletin ...

Research Article Special Issue

African Journals Online (AJOL)

2017-09-07

Sep 7, 2017 ... special experience of urban environments in the development process. ... Internet and social networking, and eventually poor performance of the police .... was shown that different regions have different levels of fear of crime.

Overview of the Health and Retirement Study and Introduction to the Special Issue.

Science.gov (United States)

Fisher, Gwenith G; Ryan, Lindsay H

2018-01-01

Twenty five years ago, the largest academic behavioral and social science project ever undertaken in the U.S. began: the Health and Retirement Study (HRS). The HRS is an invaluable publicly available dataset for investigating work, aging, and retirement and informing public policy on these issues. This biennial longitudinal study began in 1992 and has studied more than 43,000 individuals and produced almost 4000 journal articles, dissertations, books, book chapters, and reports to date. The purpose of this special issue of Work, Aging and Retirement is to describe the HRS and highlight relevant research that utilizes this rich and complex dataset. First, we briefly describe the background that led to the development of the HRS. Then we summarize key aspects of the study, including its development, sampling, and methodology. Our review of the content of the survey focuses on the aspects of the study most relevant to research on worker aging and retirement. Next, we identify key strengths and important limitations of the study and provide advice to current and future HRS data users. Finally, we summarize the articles in this Special Issue (all of which use data from the HRS) and how they advance our knowledge and understanding of worker aging and retirement.

Precision toxicology based on single cell sequencing: an evolving trend in toxicological evaluations and mechanism exploration.

Science.gov (United States)

Zhang, Boyang; Huang, Kunlun; Zhu, Liye; Luo, Yunbo; Xu, Wentao

2017-07-01

In this review, we introduce a new concept, precision toxicology: the mode of action of chemical- or drug-induced toxicity can be sensitively and specifically investigated by isolating a small group of cells or even a single cell with typical phenotype of interest followed by a single cell sequencing-based analysis. Precision toxicology can contribute to the better detection of subtle intracellular changes in response to exogenous substrates, and thus help researchers find solutions to control or relieve the toxicological effects that are serious threats to human health. We give examples for single cell isolation and recommend laser capture microdissection for in vivo studies and flow cytometric sorting for in vitro studies. In addition, we introduce the procedures for single cell sequencing and describe the expected application of these techniques to toxicological evaluations and mechanism exploration, which we believe will become a trend in toxicology.

Non-precautionary aspects of toxicology

International Nuclear Information System (INIS)

Grandjean, Philippe

2005-01-01

Empirical studies in toxicology aim at deciphering complex causal relationships, especially in regard to human disease etiologies. Several scientific traditions limit the usefulness of documentation from current toxicological research, in regard to decision-making based on the precautionary principle. Among non-precautionary aspects of toxicology are the focus on simplified model systems and the effects of single hazards, one by one. Thus, less attention is paid to sources of variability and uncertainty, including individual susceptibility, impacts of mixed and variable exposures, susceptible life-stages, and vulnerable communities. In emphasizing the need for confirmatory evidence, toxicology tends to penalize false positives more than false negatives. An important source of uncertainty is measurement error that results in misclassification, especially in regard to exposure assessment. Standard statistical analysis assumes that the exposure is measured without error, and imprecisions will usually result in an underestimation of the dose-effect relationship. In testing whether an effect could be considered a possible result of natural variability, a 5% limit for 'statistical significance' is usually applied, even though it may rule out many findings of causal associations, simply because the study was too small (and thus lacked statistical power) or because some imprecision or limited sensitivity of the parameters precluded a more definitive observation. These limitations may be aggravated when toxicology is influenced by vested interests. Because current toxicology overlooks the important goal of achieving a better characterization of uncertainties and their implications, research approaches should be revised and strengthened to counteract the innate ideological biases, thereby supporting our confidence in using toxicology as a main source of documentation and in using the precautionary principle as a decision procedure in the public policy arena

Preface to the Special Issue on "Geophysical and Climate Change Studies in Tibet, Xinjiang, and Siberia (TibXS from Satellite Geodesy"

Directory of Open Access Journals (Sweden)

Cheinway Hwang

2013-01-01

Full Text Available This special issue publishes papers on recent results in geophysical and climate change studies over Tibet, Xinjiang and Siberia (TibXS based upon some of the key sensors used in satellite geodesy, including satellite gravimetric sensors (GRACE and GOCE, satellite altimeters (TOPEX, Jason-1 and -2, and ENVISAT, and Global Positioning System satellites. Results from ground- and airborne-based geodetic observations, notably those based on airborne gravimeter, superconducting gravimeter (SG and seismometers are also included in the special issue. In all, 22 papers were submitted for this special issue; 17 papers were accepted.

The Context of Current Content Analysis of Gender Roles: An Introduction to a Special Issue

Science.gov (United States)

Popova, Lucy; Linz, Daniel G.

2010-01-01

The aim of this paper is to provide context for the quantitative content analyses of gender roles that are to be included in both parts of this special issue. First, a timeline of historical uses of the content analysis methodology is presented. Second, research objectives that frequently drive content analysis of gender roles are described; these include: to support feminist claims, to compare media with real life, to predict effects on audiences, and to detect effects of media producers on content. Third, previous content analyses published in Sex Roles and other gender-focused journals are reviewed and categorized in terms of medium, genre, time span, gender, and nationality. Finally, contributions of each of the articles in this special issue are outlined. PMID:20694031

Forthcoming Challenges in Mycotoxins Toxicology Research for Safer Food-A Need for Multi-Omics Approach.

Science.gov (United States)

Dellafiora, Luca; Dall'Asta, Chiara

2017-01-04

The presence of mycotoxins in food represents a severe threat for public health and welfare, and poses relevant research challenges in the food toxicology field. Nowadays, food toxicologists have to provide answers to food-related toxicological issues, but at the same time they should provide the appropriate knowledge in background to effectively support the evidence-based decision-making in food safety. Therefore, keeping in mind that regulatory actions should be based on sound scientific findings, the present opinion addresses the main challenges in providing reliable data for supporting the risk assessment of foodborne mycotoxins.

Special Issue: Recent Progress in the Vertical Coupling in the Atmosphere-Ionosphere System\

Czech Academy of Sciences Publication Activity Database

Pancheva, D.; Shiokawa, K.; Knížová, Petra; Wan, W.

90-91, Special Issue (2012), s. 5-6 ISSN 1364-6826 Institutional support: RVO:68378289 Keywords : ionosphere * neutral atmosphere * atmospheric waves Subject RIV: DG - Athmosphere Sciences, Meteorology OBOR OECD: Meteorology and atmospheric sciences Impact factor: 1.417, year: 2012 http://www.sciencedirect.com/science/article/pii/S1364682612002581?via%3Dihub

Research Article Special Issue

African Journals Online (AJOL)

2017-09-10

. Special ... is 4000 pps, in 1 ms there are 4 sampling intervals. Fig. .... Although this type of radar is simple, generally it is not very sensitive because of increased ... processing) to determine the true sign of Doppler frequency.

Research Article Special Issue

African Journals Online (AJOL)

2016-07-18

Jul 18, 2016 ... and 1340s, centralization and organizational unity in the early 1350s, ... appropriate productivity in specialized costs of welfare and social ..... and finally the lack of compliance with commitments by the government to the social.

Research Article Special Issue

African Journals Online (AJOL)

pc

Published online: 1 May 2018. ABSTRACT ... CMOS technology with many special features that can overcome all the limitations in CMOS. QCA is of high speed, small size ... is done depending on position of single electrons. This shows that ...

Research Article Special Issue

African Journals Online (AJOL)

pc

2018-05-01

May 1, 2018 ... such as the athletes. This is done through gene doping, ... reduced risk of injury and drug abuse, talent selection through DNA and special training ..... GJB2 gene among Malays with non-syndromic hearing loss. International ...

Introduction to the Special Issue on Autism Spectrum Disorders Approaches to Training, Teaching, and Treatment

Directory of Open Access Journals (Sweden)

Kamil ÖZERK

2016-12-01

Full Text Available The strength of an educational system rests in its design and implementation. Part of what informs the design process is knowledge of student needs and valued goals and outcomes. As systems are designed, research evidence informs the implementation process. We are pleased to present a series of articles in this special issue that will aide special educators and administrators design and implement effective educational systems for children with autism spectrum disorders.

Introduction to the Special Issue on Inequality in the Digital Environment

Directory of Open Access Journals (Sweden)

Roderick Graham

2013-11-01

Full Text Available The purpose of this special issue is to explore social inequalities in the digital environment. The motivation for this issue is derived from the disproportionate focus on technological and economic aspects of the Information Society to the detriment of sociological and cultural aspects. The research presented here falls along three dimensions of inequality. Two papers explore the ways that race orders interaction online. A second pair of papers explores the experiences of technology users with physical and mental disabilities. A final paper looks at gender, and the higher rates of intimate partner violence experienced by women online. Taken as a whole, these five papers highlight some of the ways that the digital environment can reproduce or mitigate inequalities that have been molded and routinized in the physical environment.

Research Article Special Issue

African Journals Online (AJOL)

2016-05-15

May 15, 2016 ... of specific musical terms; attention to the Quran and Ahl al-Bayt and special devotion to ... Another factor that plays a role in making the poetry of Shahriar .... world, they start reading the masterpieces of world literature and ...

EDITORIAL: Special issue: overview reports from the Fusion Energy Conference (FEC) (Daejeon, South Korea, 2010) Special issue: overview reports from the Fusion Energy Conference (FEC) (Daejeon, South Korea, 2010)

Science.gov (United States)

Thomas, Paul

2011-09-01

The group of 27 papers published in this special issue of Nuclear Fusion aims to monitor the worldwide progress made in the period 2008-2010 in the field of thermonuclear fusion. Of these papers, 22 are based on overview reports presented at the 23rd Fusion Energy Conference (FEC 2010) and five are summary reports. The conference was hosted by the Republic of Korea and organized by the IAEA in cooperation with the National Fusion Research Institute and the Daejeon Metropolitan City. It took place in Daejeon on 11-16 October 2010. The overviews presented at the conference have been rewritten and extended for the purpose of this special issue and submitted to the standard double-referee peer-review of Nuclear Fusion. The articles are placed in the following sequence: Conference summaries of the sessions devoted to: Tokamak and stellarator experiments, experimental divertor physics and plasma wall interaction experiments, stability experiments and waves and fast particles; ITER activities, fusion technology, safety and economics; Magnetic confinement theory and modelling; Inertial confinement fusion; Innovative confinement concepts, operational scenarios and confinement. Overview articles, presented in programme order, are as follows: Tokamaks Overview of KSTAR initial experiments; Recent progress in RF heating and long-pulse experiments on EAST; Overview of JET results; DIII-D contributions toward the scientific basis for sustained burning plasmas; Overview of JT-60U results toward the resolution of key physics and engineering issues in ITER and JT-60SA; Overview of physics results from NSTX; Overview of ASDEX Upgrade results; Overview of physics results from MAST; Contribution of Tore Supra in preparation of ITER; Overview of FTU results; Overview of experimental results on the HL-2A tokamak; Progress and scientific results in the TCV tokamak; Overview of the JT-60SA project; Recent results of the T-10 tokamak; The reconstruction and research progress of the TEXT

Predictive Toxicology: Current Status and Future Outlook (EBI ...

Science.gov (United States)

Slide presentation at the EBI-EMBL Industry Programme Workshop on Predictive Toxicology and the currently status of Computational Toxicology activities at the US EPA. Slide presentation at the EBI-EMBL Industry Programme Workshop on Predictive Toxicology and the currently status of Computational Toxicology activities at the US EPA.

Toxicological profile for uranium. Final report

International Nuclear Information System (INIS)

1990-12-01

The ATSDR Toxicological Profile for Uranium is intended to characterize succinctly the toxicological and health effects information for the substance. It identifies and reviews the key literature that describes the substances's toxicological properties. Other literature is presented but described in less detail. The profile is not intended to be an exhaustive document; however, more comprehensive sources of specialty information are referenced. The profile begins with a public health statement, which describes in nontechnical language the substance's relevant toxicological properties. Following the statement is material that presents levels of significant human exposure and, where known, significant health effects. The adequacy of information to determine the substance's health effects is described. Research gaps in nontoxic and health effects information are described. Research gaps that are of significance to the protection of public health will be identified in a separate effort. The focus of the document is on health and toxicological information

Toxicological profile for radon. Final report

International Nuclear Information System (INIS)

1990-12-01

The ATSDR Toxicological Profile for Radon is intended to characterize succinctly the toxicological and health effects information for the substance. It identifies and reviews the key literature that describes the substance's toxicological properties. Other literature is presented but described in less detail. The profile is not intended to be an exhaustive document; however, more comprehensive sources of specialty information are referenced. The profile begins with a public health statement, which describes in nontechnical language the substance's relevant toxicological properties. Following the statement is material that presents levels of significant human exposure and, where known, significant health effects. The adequacy of information to determine the substance's health effects is described. Research gaps in nontoxic and health effects information are described. Research gaps that are of significance to the protection of public health will be identified in a separate effort. The focus of the document is on health and toxicological information

Toxicological profile for plutonium. Final report

International Nuclear Information System (INIS)

1990-12-01

The ATSDR Toxicological Profile for Plutonium is intended to characterize succinctly the toxicological and health effects information for the substance. It identifies and reviews the key literature that describes the substance's toxicological properties. Other literature is presented but described in less detail. The profile is not intended to be an exhaustive document; however, more comprehensive sources of specialty information are referenced. The profile begins with a public health statement, which describes in nontechnical language the substance's relevant toxicological properties. Following the statement is material that presents levels of significant human exposure and, where known, significant health effects. The adequacy of information to determine the substance's health effects is described. Research gaps in nontoxic and health effects information are described. Research gaps that are of significance to the protection of public health will be identified in a separate effort. The focus of the document is on health and toxicological information

Toxicological profile for radium. Final report

International Nuclear Information System (INIS)

1990-12-01

The ATSDR Toxicological Profile for Radium is intended to characterize succinctly the toxicological and health effects information for the substance. It identifies and reviews the key literature that describes the substances' toxicological properties. Other literature is presented but described in less detail. The profile is not intended to be an exhaustive document; however, more comprehensive sources of specialty information are referenced. The profile begins with a public health statement, which describes in nontechnical language the substance's relevant toxicological properties. Following the statement is material that presents levels of significant human exposure and, where known, significant health effects. The adequacy of information to determine the substance's health effects is described. Research gaps in nontoxic and health effects information are described. Research gaps that are of significance to the protection of public health will be identified in a separate effort. The focus of the document is on health and toxicological information

Introduction to the special issue - Labor Market Outcomes : A Transatlantic Perspective

OpenAIRE

Arnaud CHERON; François LANGOT

2009-01-01

The ADRES conference "Labor market outcomes: a transatlantic perspective" took place in Paris, in January 2008. It was jointly organized by the University of Le Mans and the EDHEC Business School. Approximately 40 papers were presented in plenary and parallel sessions. The plenary speakers were G. Berola, P. Cahuc, F. Kramarz, L. Ljungqvist, E. Prescott, R. Rogerson, R. Shimer, V. Rios-Rull, E. Wasmer and C. Zimmerman. A selection of the papers are published in this special issue of the "Anna...

Impact of online toxicology training on health professionals: the Global Educational Toxicology Uniting Project (GETUP).

Science.gov (United States)

Wong, Anselm; Vohra, Rais; Dawson, Andrew H; Stolbach, Andrew

2017-11-01

The Global Educational Toxicology Uniting Project (GETUP), supported by the American College of Medical Toxicology, links countries with and without toxicology services via distance education with the aim to improve education. Due to the lack of toxicology services in some countries there is a knowledge gap in the management of poisonings. We describe our experience with the worldwide delivery of an online introductory toxicology curriculum to emergency doctors and other health professionals treating poisoned patients. We delivered a 15-module introductory Internet-based toxicology curriculum to emergency doctors and health professionals, conducted from August to December 2016. This Internet-based curriculum was adapted from one used to teach emergency residents toxicology in the United States. Modules covered themes such as pharmaceutical (n = 8), toxidromes (n = 2) and agrochemicals (n = 5) poisoning. Participants completed pre-test and post-test multiple choice questions (MCQs) before and after completing the online module, respectively, throughout the course. We collected information on participant demographics, education and training, and perception of relevance of the curriculum. Participants gave feedback on the course and how it affected their practice. One hundred and thirty-six health professionals from 33 countries participated in the course: 98 emergency doctors/medical officers, 25 physicians, eight pharmacists/poisons information specialists, two toxicologists, two medical students and one nurse. Median age of participants was 34 years. Median number of years postgraduate was seven. Ninety (65%) had access to either a poisons information centre over the phone or toxicologist and 48 (35%) did not. All participants expected the course to help improve their knowledge. Overall median pre-module MCQ scores were 56% (95%CI: 38, 75%) compared to post-module MCQ scores median 89% (95% CI: 67, 100%) (p education to health professionals treating

Research Article Special Issue

African Journals Online (AJOL)

pc

2017-08-08

Aug 8, 2017 ... Special attention is paid to human capital agglomeration, which is regarded as a .... the innovation sector, on the periphery of the ... Agglomeration is an effective form of concentration of human capital, intellectual ... participants of social relations (public, entrepreneurs) or the formation of clusters, emerging.

Toxicology of organic-inorganic hybrid molecules: bio-organometallics and its toxicology.

Science.gov (United States)

Fujie, Tomoya; Hara, Takato; Kaji, Toshiyuki

2016-01-01

Bio-organometallics is a research strategy of biology that uses organic-inorganic hybrid molecules. The molecules are expected to exhibit useful bioactivities based on the unique structure formed by interaction between the organic structure and intramolecular metal(s). However, studies on both biology and toxicology of organic-inorganic hybrid molecules have been incompletely performed. There can be two types of toxicological studies of bio-organometallics; one is evaluation of organic-inorganic hybrid molecules and the other is analysis of biological systems from the viewpoint of toxicology using organic-inorganic hybrid molecules. Our recent studies indicate that cytotoxicity of hybrid molecules containing a metal that is nontoxic in inorganic forms can be more toxic than that of hybrid molecules containing a metal that is toxic in inorganic forms when the structure of the ligand is the same. Additionally, it was revealed that organic-inorganic hybrid molecules are useful for analysis of biological systems important for understanding the toxicity of chemical compounds including heavy metals.

A special issue devoted to gold deposits in northern Nevada: Part 2. Carlin-type Deposits

Science.gov (United States)

Hofstra, Albert H.; John, David A.; Theodore, Ted G.

2003-01-01

This is the second of two special issues of Economic Geology devoted to gold deposits in northern Nevada. Readers interested in a general overview of these deposits, their economic significance, their context within the tectonic evolution of the region, and synoptic references on each gold deposit type are directed to the preface of the first special issue (John et al., 2003). Volume 98, issue 2, contains five papers that address regional aspects important to the genesis of gold deposits in northern Nevada and five papers that present detailed studies of epithermal deposits and districts. All of the regional papers are pertinent to Carlin-type gold deposits, because they address the age of mineralization (Arehart et al., 2003), origin and evolutionary history of the northwest-striking mineral belts that localize many deposits (Grauch et al., 2003), nature of the middle and lower crust below these mineral belts (Howard, 2003), district- to deposit-scale stream sediment and lithogeochemical anomalies (Theodore et al., 2003), and stratigraphy and structure of a district located along a northeast-striking lineament (Peters et al., 2003).

Research Article Special Issue

African Journals Online (AJOL)

pc

2018-04-18

Apr 18, 2018 ... WORLD THROUGH THE PRISM OF THE INTERNATIONAL FESTIVAL ... It has been explored by many a Russian and foreign researcher. ... attempt to focus, instead of going back to the analysis of past experience, on the subject from ... intercultural interaction between various nations, was given special ...

Research Article Special Issue

African Journals Online (AJOL)

2017-02-15

Feb 15, 2017 ... they have no special development plan and their authorities actually do not know about the ... Keywords: Converted villages to city centers, urban network, SWOT analysis, ... rural areas and can decrease regional differences in developing ... Small scale cities are necessary for integration of rural and urban.

Research Article Special Issue

African Journals Online (AJOL)

2016-06-15

Jun 15, 2016 ... International License. ... confirmatory factor analysis which is a technique to study the structure of a ... School as a social institution is part of a special community that has ... specifies the amount of support that teacher thinks that students ..... social adjustment and academic performance in third grade female ...

Special Issue “50th Anniversary of the Kohn–Sham Theory—Advances in Density Functional Theory”

Directory of Open Access Journals (Sweden)

Ágnes Nagy

2016-11-01

Full Text Available The properties of many materials at the atomic scale depend on the electronic structure, which requires a quantum mechanical treatment. The most widely used approach to make such a treatment feasible is density functional theory (DFT, the advances in which were presented and discussed during the DFT conference in Debrecen. Some of these issues are presented in this Special Issue.

Special Issue: Aviation Alternative Fuels

Directory of Open Access Journals (Sweden)

Yang Zhang

2014-12-01

Full Text Available The investigation of aviation alternative fuels has increased significantly in recent years in an effort to reduce the environment and climate impact by aviation industry. Special requirements have to be met for qualifying as a suitable aviation fuel. The fuel has to be high in energy content per unit of mass and volume, thermally stable and avoiding freezing at low temperatures. There are also many other special requirements on viscosity, ignition properties and compatibility with the typical aviation materials. There are quite a few contending alternative fuels which can be derived from coal, natural gas and biomass.[...

Developmental and Reproductive Toxicology Database (DART)

Data.gov (United States)

U.S. Department of Health & Human Services — A bibliographic database on the National Library of Medicine's (NLM) Toxicology Data Network (TOXNET) with references to developmental and reproductive toxicology...

On-line sources of toxicological information in Canada

International Nuclear Information System (INIS)

Racz, William J.; Ecobichon, Donald J.; Baril, Marc

2003-01-01

This paper will provide an overview of the on-line resources available in toxicology in Canada. It will describe a brief history of The Society of Toxicology of Canada, with reference to other societies and also provide information on education, research and other resources related to toxicology. Toxicology in Canada emerged as a distinct and vibrant discipline following the thalidomide tragedy of the 1960s. In the pharmaceutical industry and government, toxicology was readily established as an essential component of drug development and safety, and as the need for toxicologists expanded, training programs were established, usually in collaboration with departments of pharmacology. In the last two to three decades other disciplines, environmental biology, analytical chemistry and epidemiology joined the ranks of toxicology. The on-line sources of toxicology information are rapidly expanding. This article describes those sources considered by the authors to be important from a national and international perspective. The majority of these sources are professional organizations and government agencies

Special issue on graphene nanophotonics

Science.gov (United States)

Nikitin, A. Yu; Maier, S. A.; Martin-Moreno, L.

2013-11-01

Graphene nanophotonics has recently appeared as a new research area, which combines the topics of nanophotonics (devoted to studying the behavior of electromagnetic fields on the deep subwavelength scale) and the several extraordinary material properties of graphene. Apart from being the thinnest existing material, graphene is very attractive for photonics due to its extreme flexibility, high mobility and the possibility of controlling its carrier concentration (and hence its electromagnetic response) via external gate voltages. From its very birth, graphene nanophotonics has the potential for innovative technological applications, aiming to complement (or in some cases even replace) the existing semiconductor/metallic photonic platforms. It has already shown exceptional capabilities in many directions, such as for instance in photodetection, photovoltaics, lasing, etc [1]. A special place in graphene photonics belongs to graphene plasmonics, which studies both intrinsic plasmons in graphene and the combination of graphene with plasmons supported by metallic structures [2]. Here, apart from the dynamic control via external voltages previously mentioned, the use of graphene brings with it the remarkable property that graphene plasmons have a wavelength λp that can be even one hundred times smaller than that in free space λ (for instance λp ~ 100 nm at λ ~ 10 μm). This provides both extreme confinement and extreme enhancement of the electromagnetic field at the graphene sheet which, together with its high sensitivity to the doping level, opens many interesting perspectives for new optical devices. The collection of papers presented in this special issue highlights different aspects of nanophotonics in graphene and related systems. The timely appearance of this publication was apparent during the monographic workshop 'Graphene Nanophotonics', sponsored by the European Science Foundation and held during 3-8 March 2013, in Benasque (Spain). This special issue

Predictive toxicology: the paths of the future

International Nuclear Information System (INIS)

Detilleux, Ph.; Vallier, L.; Legallais, C.; Leclerc, E.; Prot, J.M.; Choucha, L.; Baudoin, R.; Dufresne, M.; Gautier, A.; Carpentier, B.; Mansuy, D.; Pery, A.; Brochot, C.; Manivet, Ph.; Rabilloud, Th.; Spire, C.; Coumoul, X.; Junot, Ch.; Laprevote, O.; Le pape, A.; Le Guevel, R.; Tourneur, E.; Ben Mkaddem, S.; Chassin, C.; Aloulou, M.; Goujon, J.M.; Hertif, A.; Ouali, N.; Vimont, S.; Monteiro, R.; Rondeau, E.; Elbim, C.; Werts, C.; Vandewalle, A.; Ben Mkaddem, S.; Pedruzzi, E.; Coant, N.; Bens, M.; Cluzeaud, F.; Ogier-Denis, E.; Pongnimitprasert, N.; Babin-Chevaye, C.; Fay, M.; Bernard, M.; Dupuy, C.; Ei Benna, J.; Gougerot-Pocidale, M.A.; Braut-Boucher, F.; Pinton, Ph.; Lucioli, J.; Tsybulskyy, D.; Joly, B.; Laffitte, J.; Bourges-Abella, N.; Oswald, I.P.; Kolf-Clauw, M.; Pierre, St.; Bats, A.S.; Chevallier, A.; Bui, L.Ch.; Ambolet-Camoit, A.; Garlatti, M.; Aggerbeck, M.; Barouki, R.; Al Khansa, I.; Blanck, O.; Guillouzo, A.; Bars, R.; Rouas, C.; Bensoussan, H.; Suhard, D.; Tessier, C.; Grandcolas, L.; Pallardy, M.; Gueguen, Y.; Sparfel, L.; Pinel-Marie, M.L.; Boize, M.; Koscielny, S.; Desmots, S.; Pery, A.; Fardel, O.; Alvergnas, M.; Rouleau, A.; Lucchi, G.; Mantion, G.; Heyd, B.; Richert, L.; Ducoroy, P.; Martin, H.; Val, St.; Martinon, L.; Cachier, H.; Yahyaoui, A.; Marfaing, H.; Baeza-Squiban, A.; Martin-Chouly, C.; Bonvallet, M.; Morzadec, C.; Fardel, O.; Vernhet, L.; Baverel, G.; El Hage, M.; Nazaret, R.; Conjard-Duplany, A.; Ferrier, B.; Martin, G.; Legendre, A.; Desmots, S.; Lecomte, A.; Froment, P.; Habert, R.; Lemazurier, E.; Robinel, F.; Dupont, O.; Sanfins, E.; Dairou, J.; Chaffotte, A.F.; Busi, F.; Rodrigues Lima, F.; Dupret, J.M.; Mayati, A.; Le Ferrec, E.; Levoin, N.; Paris, H.; Uriac, Ph.; N'Diaye, M.; Lagadic-Gossmann, D.; Fardel, O.; Assemat, E.; Boublil, L.; Borot, M.C.; Marano, F.; Baeza-Squiban, A.; Martiny, V.Y.; Moroy, G.; Badel, A.; Miteva, M.A.; Hussain, S.; Ferecatu, I.; Borot, C.; Andreau, K.; Baeza-Squiban, A.; Marano, F.; Boland, S.; Leroux, M.; Zucchini-Pascal, N.; Peyre, L.; Rahmani, R.; Buron, N.; Porcedou, M.; Fromenty, B.; Borgne-Sanchez, A.; Rogue, A.; Spire, C.; Claude, N.; Guillouzo, A.

2010-01-01

Prevention of possible noxious effects in relation with the exposure to one or several chemical, physical or biological agents present in our domestic or professional environment is one of today's big public health stakes. Another stake is the better assessment of the risks linked with the use of health-care products. The efficacy and predictiveness of toxicology studies are directly related to the combination of alternate complementary methods and animal experiments (obtaining data from different species and with different models: in vitro, ex vivo and in vivo). Despite important efforts, the toxicological evaluation remains perfectible. The proceedings of this 2010 congress of the French Society of cell pharmaco-toxicology deal with recent advances, both scientific and technological, in 'predictive toxicology'. Four main topics are approached: cell and organ models, 'omics', in silico modeling, and new technologies (imaging, cell ships, high-speed processing). Among the different presentations, 3 abstracts present some recent advances in imaging techniques applied to toxicology studies. These are: 1 - first uses in toxicology of TOF-SIMS mass spectroscopy imaging (O. Laprevote, Paris-Descartes Univ. (FR)); 2 - Small animal imaging, a tool for predictive toxicology (A. Le Pape, CNRS Orleans (FR)); 3 - uranium localization at cell level using SIMS imaging technique (C. Rouas et al., IRSN Fontenay-aux-Roses (FR)). (J.S.)

40 CFR 161.340 - Toxicology data requirements.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Toxicology data requirements. 161.340... Toxicology data requirements. (a) Table. Sections 161.100 through 161.102 describe how to use this table to determine the toxicology data requirements and the substance to be tested. Kind of data required (b) Notes...

Data governance in predictive toxicology: A review.

Science.gov (United States)

Fu, Xin; Wojak, Anna; Neagu, Daniel; Ridley, Mick; Travis, Kim

2011-07-13

Due to recent advances in data storage and sharing for further data processing in predictive toxicology, there is an increasing need for flexible data representations, secure and consistent data curation and automated data quality checking. Toxicity prediction involves multidisciplinary data. There are hundreds of collections of chemical, biological and toxicological data that are widely dispersed, mostly in the open literature, professional research bodies and commercial companies. In order to better manage and make full use of such large amount of toxicity data, there is a trend to develop functionalities aiming towards data governance in predictive toxicology to formalise a set of processes to guarantee high data quality and better data management. In this paper, data quality mainly refers in a data storage sense (e.g. accuracy, completeness and integrity) and not in a toxicological sense (e.g. the quality of experimental results). This paper reviews seven widely used predictive toxicology data sources and applications, with a particular focus on their data governance aspects, including: data accuracy, data completeness, data integrity, metadata and its management, data availability and data authorisation. This review reveals the current problems (e.g. lack of systematic and standard measures of data quality) and desirable needs (e.g. better management and further use of captured metadata and the development of flexible multi-level user access authorisation schemas) of predictive toxicology data sources development. The analytical results will help to address a significant gap in toxicology data quality assessment and lead to the development of novel frameworks for predictive toxicology data and model governance. While the discussed public data sources are well developed, there nevertheless remain some gaps in the development of a data governance framework to support predictive toxicology. In this paper, data governance is identified as the new challenge in

Data governance in predictive toxicology: A review

Directory of Open Access Journals (Sweden)

Fu Xin

2011-07-01

Full Text Available Abstract Background Due to recent advances in data storage and sharing for further data processing in predictive toxicology, there is an increasing need for flexible data representations, secure and consistent data curation and automated data quality checking. Toxicity prediction involves multidisciplinary data. There are hundreds of collections of chemical, biological and toxicological data that are widely dispersed, mostly in the open literature, professional research bodies and commercial companies. In order to better manage and make full use of such large amount of toxicity data, there is a trend to develop functionalities aiming towards data governance in predictive toxicology to formalise a set of processes to guarantee high data quality and better data management. In this paper, data quality mainly refers in a data storage sense (e.g. accuracy, completeness and integrity and not in a toxicological sense (e.g. the quality of experimental results. Results This paper reviews seven widely used predictive toxicology data sources and applications, with a particular focus on their data governance aspects, including: data accuracy, data completeness, data integrity, metadata and its management, data availability and data authorisation. This review reveals the current problems (e.g. lack of systematic and standard measures of data quality and desirable needs (e.g. better management and further use of captured metadata and the development of flexible multi-level user access authorisation schemas of predictive toxicology data sources development. The analytical results will help to address a significant gap in toxicology data quality assessment and lead to the development of novel frameworks for predictive toxicology data and model governance. Conclusions While the discussed public data sources are well developed, there nevertheless remain some gaps in the development of a data governance framework to support predictive toxicology. In this paper

Current role of ICP-MS in clinical toxicology and forensic toxicology: a metallic profile.

Science.gov (United States)

Goullé, Jean-Pierre; Saussereau, Elodie; Mahieu, Loïc; Guerbet, Michel

2014-08-01

As metal/metalloid exposure is inevitable owing to its omnipresence, it may exert toxicity in humans. Recent advances in metal/metalloid analysis have been made moving from flame atomic absorption spectrometry and electrothermal atomic absorption spectrometry to the multi-elemental inductively coupled plasma (ICP) techniques as ICP atomic emission spectrometry and ICP-MS. ICP-MS has now emerged as a major technique in inorganic analytical chemistry owing to its flexibility, high sensitivity and good reproducibility. This in depth review explores the ICP-MS metallic profile in human toxicology. It is now routinely used and of great importance, in clinical toxicology and forensic toxicology to explore biological matrices, specifically whole blood, plasma, urine, hair, nail, biopsy samples and tissues.

Space Toxicology: Environmental Health Considerations during Spaceflight Operations and Potential Paths for Research

Science.gov (United States)

Khan-Mayberry, Noreen N.; Sundaresan, Alemalu

2009-01-01

Space Toxicology is a specialized discipline for spaceflight, space habitation and occupation of celestial bodies including planets, moons and asteroids [1]. Astronaut explorers face unique challenges to their health while working and living with limited resources for rescue and medical care during space operation. At its core the practice of space toxicology to identify, assess and predict potential chemical contaminants and limit the astronaut s exposure to these environmental factors in order to protect crew health. Space toxicologists are also charged with setting safe exposure limits that will protect the astronaut against a multitude of chemical exposures, in a physiologically altered state. In order to maintain sustained occupation in space, toxicological risks are gauged and managed within the context of isolation, continual exposures, reuse of air and water, limited rescue options, and the necessary use of highly toxic compounds required for propulsion. As the space program move towards human presence and exploration other celestial bodies in situ toxicological risks, such as inhalation of unusual and/or reactive mineral dusts must also be analyzed and controlled. Placing humans for long-term presence in space creates several problems and challenges to the long-term health of the crew, such as bone-loss and immunological challenges and has spurred research into acute, chronic and episodic exposure of the pulmonary system to mineral dusts [2]. NASA has demonstrated that lunar soil contains several types of reactive dusts, including an extremely fine respirable component. In order to protect astronaut health, NASA is now investigating the toxicity of this unique class of dusts. Understanding how these reactive components behave "biochemically" in a moisture-rich pulmonary environment will aid in determining how toxic these particles are to humans. The data obtained from toxicological examination of lunar dusts will determine the human risk criteria for lunar

Repeating Marx: Introduction to the Special Issue “Karl Marx @ 200: Debating Capitalism & Perspectives for the Future of Radical Theory”

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Christian Fuchs

2018-05-01

Full Text Available This introduction sets out the context of the special issue “Karl Marx @ 200: Debating Capitalism & Perspectives for the Future of Radical Theory”, which was published on the occasion of Marx’s bicentenary on 5 May 2018. First, we give a brief overview of contemporary capitalism’s development and its crises. Second, we argue that it is important to repeat Marx today. Third, we reflect on lessons learned from 200 years of struggles for alternatives to capitalism. Fourth, we give an overview of the contributions in this special issue. Taken together, the contributions in this special issue show that Marx’s theory and politics remain key inspirations for understanding exploitation and domination in 21st-century society and for struggles that aim to overcome these phenomena and establishing a just and fair society. We need to repeat Marx today.

Hair Analysis in Forensic Toxicology: An Updated Review with a Special Focus on Pitfalls.

Science.gov (United States)

Kintz, Pascal

2017-01-01

The detection of drugs in hair analysis has progressively emerged as a consequence of the enhanced sensitivity of analytical techniques used in forensic toxicology; a greater advantage in using this matrix with respect to classical ones (i.e. urine and blood) is an easier and non-invasive sample collection, even when the careful supervision of law enforcement officers is required to avoid the risk that the sample may be adulterated or replaced. Moreover, according to the length of the hair, the history of drug exposure can be retrospectively monitored from few weeks up to months or years since sample collection. Through a detailed revision of the existent literature, this manuscript provides information on the proper sample collection, preparation and analysis, as well as pitfalls in forensic hair analysis, and summarizes the wide range of application of this technology, including excessive alcohol drinking, doping, child abuse, and offences linked to drug use. Verification of history of psychotropic drugs, alcohol and doping agents use by hair analysis, hair testing for driving license regranting and drug facilitated crimes, and testing for drugs in hair of children have been reviewed together with recent trends in hair contamination and possibility to disclose use of new psychoactive substances by hair analysis. Hair analysis in forensic toxicology has been quickly emerged and improved in recent years; a deeper knowledge of advantages and limitations of this unique matrix is necessary for a better use in forensic caseworks. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

CALL FOR PAPERS: Special cluster issue on `Experimental studies of zonal flow and turbulence'

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Itoh, S.-I.

2005-07-01

Plasma Physics and Controlled Fusion (PPCF) invites submissions on the topic of `Experimental studies of zonal flow and turbulence', for consideration for a special topical cluster of articles to be published early in 2006. The topical cluster will be published in an issue of PPCF, combined with regular articles. The Guest Editor for the special cluster will be S-I Itoh, Kyushu University, Japan. There has been remarkable progress in the area of structure formation by turbulence. One of the highlights has been the physics of zonal flow and drift wave turbulence in toroidal plasmas. Extensive theoretical as well as computational studies have revealed the various mechanisms in turbulence and zonal flows. At the same time, experimental research on the zonal flow, geodesic acoustic modes and generation of global electric field by turbulence has evolved rapidly. Fast growth in reports of experimental results has stimulated further efforts to develop increased knowledge and systematic understanding. Each paper considered for the special cluster should describe the present research status and new scientific knowledge/results from the authors on experimental studies of zonal flow, geodesic acoustic modes and generation of electric field by turbulence (including studies of Reynolds-Maxwell stresses, etc). Manuscripts submitted to this special cluster in Plasma Physics and Controlled Fusion will be refereed according to the normal criteria and procedures of the journal. The Guest Editor guides the progress of the cluster from the initial open call, through the standard refereeing process, to publication. To be considered for inclusion in the special cluster, articles must be submitted by 2 September 2005 and must clearly state `for inclusion in the Turbulent Plasma Cluster'. Articles submitted after this deadline may not be included in the cluster issue but may be published in a later issue of the journal. Please submit your manuscript electronically via our web site at www

Special Issue: Plant Genetics and Biotechnology in Biodiversity

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Giandomenico Corrado

2018-03-01

Full Text Available The rapid progress and increasing affordability of novel investigation tools in plant genetics and biotechnology offer previously inaccessible opportunities for the exploitation of plant genetic diversity in agriculture. The Special Issue was lunched to highlight how new technologies are improving both genotyping and phenotyping methods, thus allowing us to uncover crop diversity and use genetic variability for plant breeding with remarkable precision and speed. Three thematic reviews report on scientific, technological, and legal advances in plant diversity and agriculture. Three contributions provide specific examples of the exploitation of different kinds of genetic resources, ranging from landraces to mutant populations. Six research articles are illustrative examples of the study of molecular and/or phenotypic diversity to address basic or applied questions in different plant species. Finally, this SI was also launched to honor the memory of Prof. Gian Tommaso Scarascia Mugnozza and a dedicated Editorial acknowledges his work in plant breeding and biodiversity protection.

Modern physics letters A special issue on hadrontherapy

CERN Document Server

2015-01-01

CERN Courier Review (Jul 8, 2016) : The applications of nuclear and particle physics to medicine have seen extraordinary development since the discovery of X-rays by Röntgen at the end of the 19th century. Medical imaging and oncologic therapy with photons and charged particles (specifically hadrons) are currently hot research topics. This special issue of Modern Physics Letters is dedicated to hadron therapy, which is the frontier of cancer radiation therapy, and aims at filling a gap in the current literature on medical physics. Through 10 invited review papers, the volume presents the basics of hadron therapy, along with the most recent scientific and technological developments in the field. The first part covers topics such as the history of hadron therapy, radiation biophysics, particle accelerators, dose-delivery systems and treatment planning. In the second part, more specific topics are treated, including dose and beam monitoring, proton computer tomography, innoacustics and microdosimetry. This vo...

Embodied Making and Design Learning - Special Issue from the Learn X Design-conference DRS/CUMULUS, Chicago 2015

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Marte Sørebø Gulliksen

2016-06-01

Full Text Available This issue of FORMakademisk features selected articles developed from papers presented at the symposium Embodied Making and Design Learning at the DRS/CUMULUS-conference LearnXDesign in Chicago, Illinois, June 28–30, 2015. This special issue was developed as an initiative by the symposium conveners. The symposium was developed by researchers from research groups in Norway, Finland and Canada to explore various aspects of embodied making in relation to design learning. The symposium was a full-day event with four sessions, seven paper presentations, a roundtable discussion, a plenary discussion and a workshop. The symposium received positive feedback, attracting many participants and stimulating engaged discussions throughout the conference. This indicates a growing awareness of the topic of embodied making and design learning. This special issue features five articles that together highlight a variety of approaches and examples of current research endeavours in relation to the theme. 

Introduction to the special issue of Radiation Protection Dosimetry

International Nuclear Information System (INIS)

Anon.

2016-01-01

This special issue is a collection of peer-reviewed articles derived from presentations at the fourth EPR BioDose Meeting, held in Hanover, NH, USA in 4-8 October 2015. Organised by The International Association of Biological and EPR Radiation Dosimetry (IABERD), this meeting was held in combination with two international conferences (The International Symposium on EPR Dosimetry and Dating and The International Conference on Biodosimetry) and a symposium (The International EPR Society). The primary focus of this conference was on medical response to events in which large numbers of individuals may be exposed to significant levels of ionising radiation; topics included biodosimetry techniques, radiation mitigators, model systems to develop countermeasures, new data from different exposure events and the implication of these methods in a radiological emergency or in terrorist attack scenarios. (authors)

Call for papers: SAJHE special issue 'Re-imagining writing retreats for academic staff in higher education'

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Guest Editors

2016-06-01

Full Text Available Call for papers for an upcoming special issue of the South African Journal of Higher Education (SAJHE in 2016: ‘Re-imagining writing retreats for academic staff in higher education’.

Inhalation Toxicology Research Institute annual report 1987-1988

International Nuclear Information System (INIS)

Mauderly, J.L.; Mewhinney, J.A.; Bechtold, W.E.; Sun, J.D.; Coons, T.A.

1988-12-01

The mission of the Inhalation Toxicology Research Institute is to investigate the magnitude of human health effects that result from the inhalation of airborne materials at home, in the work place, or in the general environment. Diseases of the respiratory tract are major causes of suffering and death, and many of these diseases are directly related to the materials that people breath. The Institute's research is directed toward obtaining a better understanding of the basic biology of the respiratory tract and the mechanisms by which inhaled materials produce respiratory disease. Special attention is focused on studying the airborne materials released by various energy technologies, as well as those associated with national defense activities. The research uses a wide-ranging, comprehensive array of investigative approaches that are directed toward characterizing the source of the airborne material, following the material through its potential transformation in the air, identifying the mechanisms that govern its inhalation and deposition in the respiratory tract, and determining the fate of these inhaled materials in the body and the health effects they produce. The ultimate objectives are to determine the roles played by inhaled materials in the development of disease processes adn to estimate the risk they pose by inhaled materials in the development of disease processes and to estimate the risk they pose to humans who may be exposed to them. This report contains brief research papers that reflect the scope and recent findings of the Institute's research funded by the U.S. Department of Energy, principally through the Office of Health and Environmental Research. The papers are divided into topical sections. The first section, Characterization of Airborne Materials and Generation of Experimental Exposure Atmospheres, reflects the Institute's capabilities for fundamental aerosol research and the application of that expertise to toxicological studies. The second

Inhalation Toxicology Research Institute annual report 1987-1988

Energy Technology Data Exchange (ETDEWEB)

Mauderly, J L; Mewhinney, J A; Bechtold, W E; Sun, J D; Coons, T A [eds.

1988-12-01

The mission of the Inhalation Toxicology Research Institute is to investigate the magnitude of human health effects that result from the inhalation of airborne materials at home, in the work place, or in the general environment. Diseases of the respiratory tract are major causes of suffering and death, and many of these diseases are directly related to the materials that people breath. The Institute's research is directed toward obtaining a better understanding of the basic biology of the respiratory tract and the mechanisms by which inhaled materials produce respiratory disease. Special attention is focused on studying the airborne materials released by various energy technologies, as well as those associated with national defense activities. The research uses a wide-ranging, comprehensive array of investigative approaches that are directed toward characterizing the source of the airborne material, following the material through its potential transformation in the air, identifying the mechanisms that govern its inhalation and deposition in the respiratory tract, and determining the fate of these inhaled materials in the body and the health effects they produce. The ultimate objectives are to determine the roles played by inhaled materials in the development of disease processes adn to estimate the risk they pose by inhaled materials in the development of disease processes and to estimate the risk they pose to humans who may be exposed to them. This report contains brief research papers that reflect the scope and recent findings of the Institute's research funded by the U.S. Department of Energy, principally through the Office of Health and Environmental Research. The papers are divided into topical sections. The first section, Characterization of Airborne Materials and Generation of Experimental Exposure Atmospheres, reflects the Institute's capabilities for fundamental aerosol research and the application of that expertise to toxicological studies. The second

Advancing environmental toxicology through chemical dosimetry: External exposures versus tissue residues

Science.gov (United States)

McCarty, L.S.; Landrum, P.F.; Luoma, S.N.; Meador, J.P.; Merten, A.A.; Shephard, B.K.; van Wezelzz, A.P.

2011-01-01

The tissue residue dose concept has been used, although in a limited manner, in environmental toxicology for more than 100 y. This review outlines the history of this approach and the technical background for organic chemicals and metals. Although the toxicity of both can be explained in tissue residue terms, the relationship between external exposure concentration, body and/or tissues dose surrogates, and the effective internal dose at the sites of toxic action tends to be more complex for metals. Various issues and current limitations related to research and regulatory applications are also examined. It is clear that the tissue residue approach (TRA) should be an integral component in future efforts to enhance the generation, understanding, and utility of toxicity testing data, both in the laboratory and in the field. To accomplish these goals, several key areas need to be addressed: 1) development of a risk-based interpretive framework linking toxicology and ecology at multiple levels of biological organization and incorporating organism-based dose metrics; 2) a broadly applicable, generally accepted classification scheme for modes/mechanisms of toxic action with explicit consideration of residue information to improve both single chemical and mixture toxicity data interpretation and regulatory risk assessment; 3) toxicity testing protocols updated to ensure collection of adequate residue information, along with toxicokinetics and toxicodynamics information, based on explicitly defined toxicological models accompanied by toxicological model validation; 4) continued development of residueeffect databases is needed ensure their ongoing utility; and 5) regulatory guidance incorporating residue-based testing and interpretation approaches, essential in various jurisdictions. ??:2010 SETAC.

EU Framework 6 Project: Predictive Toxicology (PredTox)-overview and outcome

International Nuclear Information System (INIS)

Suter, Laura; Schroeder, Susanne; Meyer, Kirstin; Gautier, Jean-Charles; Amberg, Alexander; Wendt, Maria; Gmuender, Hans; Mally, Angela; Boitier, Eric; Ellinger-Ziegelbauer, Heidrun; Matheis, Katja; Pfannkuch, Friedlieb

2011-01-01

In this publication, we report the outcome of the integrated EU Framework 6 Project: Predictive Toxicology (PredTox), including methodological aspects and overall conclusions. Specific details including data analysis and interpretation are reported in separate articles in this issue. The project, partly funded by the EU, was carried out by a consortium of 15 pharmaceutical companies, 2 SMEs, and 3 universities. The effects of 16 test compounds were characterized using conventional toxicological parameters and 'omics' technologies. The three major observed toxicities, liver hypertrophy, bile duct necrosis and/or cholestasis, and kidney proximal tubular damage were analyzed in detail. The combined approach of 'omics' and conventional toxicology proved a useful tool for mechanistic investigations and the identification of putative biomarkers. In our hands and in combination with histopathological assessment, target organ transcriptomics was the most prolific approach for the generation of mechanistic hypotheses. Proteomics approaches were relatively time-consuming and required careful standardization. NMR-based metabolomics detected metabolite changes accompanying histopathological findings, providing limited additional mechanistic information. Conversely, targeted metabolite profiling with LC/GC-MS was very useful for the investigation of bile duct necrosis/cholestasis. In general, both proteomics and metabolomics were supportive of other findings. Thus, the outcome of this program indicates that 'omics' technologies can help toxicologists to make better informed decisions during exploratory toxicological studies. The data support that hypothesis on mode of action and discovery of putative biomarkers are tangible outcomes of integrated 'omics' analysis. Qualification of biomarkers remains challenging, in particular in terms of identification, mechanistic anchoring, appropriate specificity, and sensitivity.

The pharmacology and toxicology of three new biologic agents used in pulmonary medicine.

Science.gov (United States)

Albertson, T E; Walby, W F; Allen, R P; Tharratt, R S

1995-01-01

Biological agents have played an important role in the evolution of modern medical therapeutics. Recent advances in biologicals have in part been stimulated by the biotechnology revolution seen over the last several years. Toxicologists need to be aware of the proposed mechanisms and approved and experimental uses of these new biologic agents. Further, controversies about their use, efficacy, cost issues and potential toxicities should be known. Often these drugs are designed for small patient populations thus limiting the availability of human toxicological data bases. This paper reviews the pharmacology and toxicology of three new biologics (recombinant human DNase I, alpha 1-protease inhibitor, and nitric oxide). These agents appear to have important roles in treating specific diseases or disease states seen in pulmonary medicine.

Managing and developing key supplier relationships : An introduction to the special issue, discussion and implications

NARCIS (Netherlands)

Ivens, B.; van de Vijver, M.A.R.; Vos, G.C.J.M.

2013-01-01

This article provides an introduction to this special issue on managing and developing key supplier relationships. Key suppliers are increasingly seen as strategic assets of buying companies which need careful nurturing to fully utilize their potential for value creation. The six articles of this

"Children, Youth and Environments" (CYE) Announces a Special Issue on Greening Early Childhood Education

Science.gov (United States)

Bailie, Patti; Rosenow, Nancy

2014-01-01

The collection of papers contained in this special issue was elicited by a worldwide call for papers to explore settings that provided nature experiences for young children, with attention given to the effects that these initiatives have on the holistic development and environmental awareness of the children, as well as impacts on the teachers and…

Toxicological profile for thorium. Draft report (Final)

International Nuclear Information System (INIS)

1990-10-01

The ATSDR Toxicological Profile for Thorium is intended to characterize succinctly the toxicological and health effects information for the substance. It identifies and reviews the key literature that describes the substance's toxicological properties. Other literature is presented but described in less detail. The profile is not intended to be an exhaustive document; however, more comprehensive sources of specialty information are referenced. The profile begins with a public health statement, which describes in nontechnical language the substance's relevant toxicological properties. Following the statement is material that presents levels of significant human exposure and, where known, significant health effects. The adequacy of information to determine the substance's health effects is described. Research gaps in nontoxic and health effects information are described. Research gaps that are of significance to the protection of public health will be identified in a separate effort. The focus of the document is on health and toxicological information

Biodiversity, ecosystem functions and services in environmental risk assessment: introduction to the special issue.

Science.gov (United States)

Schäfer, Ralf B

2012-01-15

This Special Issue focuses on the questions if and how biodiversity, ecosystem functions and resulting services could be incorporated into the Ecological Risk Assessment (ERA). Therefore, three articles provide a framework for the integration of ecosystem services into ERA of soils, sediments and pesticides. Further articles demonstrate ways how stakeholders can be integrated into an ecosystem service-based ERA for soils and describe how the current monitoring could be adapted to new assessment endpoints that are directly linked to ecosystem services. Case studies show that the current ERA may not be protective for biodiversity, ecosystem functions and resulting services and that both pesticides and salinity currently adversely affect ecosystem functions in the field. Moreover, ecological models can be used for prediction of new protection goals and could finally support their implementation into the ERA. Overall, the Special Issue stresses the urgent need to enhance current procedures of ERA if biodiversity, ecosystem functions and resulting services are to be protected. Copyright © 2011 Elsevier B.V. All rights reserved.

Retrospective Mining of Toxicology Data to Discover Multispecies Effects: Anemia as a Case Study (SOT)

Science.gov (United States)

In vivo toxicology data is subject to multiple sources of uncertainty: observer severity bias (a pathologist may record only more severe effects and ignore less severe ones); dose spacing issues (this can lead to missing data, e.g. if a severe effect has a less severe precursor, ...

Twenty years of functional near-infrared spectroscopy: introduction for the special issue.

Science.gov (United States)

Boas, David A; Elwell, Clare E; Ferrari, Marco; Taga, Gentaro

2014-01-15

Papers from four different groups were published in 1993 demonstrating the ability of functional near infrared spectroscopy (fNIRS) to non-invasively measure hemoglobin concentration responses to brain function in humans. This special issue commemorates the first 20years of fNIRS research. The 9 reviews and 49 contributed papers provide a comprehensive survey of the exciting advances driving the field forward and of the myriad of applications that will benefit from fNIRS. Copyright © 2013 Elsevier Inc. All rights reserved.

Special Issue: Current Trends in Research in Accounting Finance and Management Control

OpenAIRE

Lassala, Carlos; Ripoll Feliu, Vicente

2017-01-01

On January 27, 2016, an agreement was signed with OmniaScience to select articles to be published in the journal Intangible Capital, in a special issue titled "Current Trends in Research in Accounting, Finance and Management Control." The agreement was reached within the framework of three events at the University of Valencia, from June 27 to 30, 2016: XXI Workshop on Accounting and Management Control. “Memorial Raymond Konopka”, X Iberoamerican Congress of Management Accounting, III  Int...

Special Issue on ActorNetwork Theory, Value CoCreation and Design in Open Innovation Environments

DEFF Research Database (Denmark)

Tanev, Stoyan; Storni, Cristiano; Stuedahl, Dagny

2015-01-01

The present special issue focuses on the application of ANT to the articulation of a cocreative perspective on design in open innovation environments. The Editors invited submissions by authors using ANT to explore and discuss the link between value co-creation, design and innovation and especially...

Discrete Mathematics - Special Issue: Graph Theory - dedicated to Carsten Thomassen on his 60th birthday

DEFF Research Database (Denmark)

2011-01-01

Carsten Thomassen belongs to the worlds's absolute top graph theorists, and to the world's top mathematicians in general. The special issue is a rather somewhat random collection of good papers in graph theory, by many different authors, dedicated to Carsten Thomassen on his 60th birthday. Guest ...

Introduction: Special issue on advances in topobathymetric mapping, models, and applications

Science.gov (United States)

Gesch, Dean B.; Brock, John C.; Parrish, Christopher E.; Rogers, Jeffrey N.; Wright, C. Wayne

2016-01-01

Detailed knowledge of near-shore topography and bathymetry is required for many geospatial data applications in the coastal environment. New data sources and processing methods are facilitating development of seamless, regional-scale topobathymetric digital elevation models. These elevation models integrate disparate multi-sensor, multi-temporal topographic and bathymetric datasets to provide a coherent base layer for coastal science applications such as wetlands mapping and monitoring, sea-level rise assessment, benthic habitat mapping, erosion monitoring, and storm impact assessment. The focus of this special issue is on recent advances in the source data, data processing and integration methods, and applications of topobathymetric datasets.

Proceedings of the 2016 National Toxicology Program Satellite Symposium.

Science.gov (United States)

Elmore, Susan A; Chen, Vivian S; Hayes-Bouknight, Schantel; Hoane, Jessica S; Janardhan, Kyathanahalli; Kooistra, Linda H; Nolte, Thomas; Szabo, Kathleen A; Willson, Gabrielle A; Wolf, Jeffrey C; Malarkey, David E

2017-01-01

The 2016 annual National Toxicology Program Satellite Symposium, entitled "Pathology Potpourri" was held in San Diego, CA, at the Society of Toxicologic Pathology's (STP) 35th annual meeting. The goal of this symposium was to present and discuss challenging diagnostic pathology and/or nomenclature issues. This article presents summaries of the speakers' talks, along with select images that were used by the audience for voting and discussion. Some lesions and topics covered during the symposium included malignant glioma and histiocytic sarcoma in the rodent brain; a new statistical method designed for histopathology data evaluation; uterine stromal/glandular polyp in a rat; malignant plasma cell tumor in a mouse brain; Schwann cell proliferative lesions in rat hearts; axillary schwannoma in a cat; necrosis and granulomatous inflammation in a rat brain; adenoma/carcinoma in a rat adrenal gland; hepatocyte maturation defect and liver/spleen hematopoietic defects in an embryonic mouse; distinguishing malignant glioma, malignant mixed glioma, and malignant oligodendroglioma in the rat; comparison of mammary gland whole mounts and histopathology from mice; and discussion of the International Harmonization of Nomenclature and Diagnostic Criteria collaborations.

Guest editorial for the special issue ‘‘Tectonics of Bay of Bengal and Arabian Sea with special emphasis on coastal and marine geohazards’’

Digital Repository Service at National Institute of Oceanography (India)

Murthy, K.S.R.; Chaubey, A.K.; Radhakrishna, M.

selected for this special issue. These include five papers dealing with various aspects of seismogenesis, structural heterogeneity and tsunami-related studies in the Andaman-Sumatra region, one paper on 3D seismic structure in Kachchh region affected...

Developmental toxicology: adequacy of current methods.

Science.gov (United States)

Peters, P W

1998-01-01

Toxicology embraces several disciplines such as carcinogenicity, mutagenicity and reproductive toxicity. Reproductive toxicology is concerned with possible effects of substances on the reproductive process, i.e. on sexual organs and their functions, endocrine regulation, fertilization, transport of the fertilized ovum, implantation, and embryonic, fetal and postnatal development, until the end-differentiation of the organs is achieved. Reproductive toxicology is divided into areas related to male and female fertility, and developmental toxicology. Developmental toxicology can be further broken down into prenatal and postnatal toxicology. Today, much new information is available about the origins of developmental disorders resulting from chemical exposure. While these findings seem to promise important new developments in methodology and research, there is a danger of losing sight of the precepts and principles established in the light of existing knowledge. There is also a danger that we may fail to correct shortcomings in our existing procedures and practice. The aim of this presentation is to emphasize the importance of testing substances for their impact in advance of their use and to underline that we must use the best existing tools for carrying out risk assessments. Moreover, it needs to be stressed that there are many substances that are never assessed with respect to reproductive and developmental toxicity. Similarly, our programmes for post-marketing surveillance with respect to developmental toxicology are grossly inadequate. Our ability to identify risks to normal development and reproduction would be much improved, first if a number of straightforward precepts were always followed and second, if we had a clearer understanding of what we mean by risk and acceptable levels of risk in the context of development. Other aims of this paper are: to stress the complexity of the different stages of normal prenatal development; to note the principles that are

Perovskite Catalysts—A Special Issue on Versatile Oxide Catalysts

Directory of Open Access Journals (Sweden)

Yu-Chuan Lin

2014-08-01

Full Text Available Perovskite-type catalysts have been prominent oxide catalysts for many years due to attributes such as flexibility in choosing cations, significant thermal stability, and the unique nature of lattice oxygen. Nearly 90% metallic elements of the Periodic Table can be stabilized in perovskite’s crystalline framework [1]. Moreover, by following the Goldschmidt rule [2], the A- and/or B-site elements can be partially substituted, making perovskites extremely flexible in catalyst design. One successful example is the commercialization of noble metal-incorporated perovskites (e.g., LaFe0.57Co0.38Pd0.05O3 for automotive emission control used by Daihatsu Motor Co. Ltd. [3]. Thus, growing interest in, and application of perovskites in the fields of material sciences, heterogeneous catalysis, and energy storage have prompted this Special Issue on perovskite catalysts. [...

[Clinical toxicology of the Academy: yesterday, today and tomorrow].

Science.gov (United States)

Sofronov, G A; Khalimov, Iu Sh; Matveev, S Iu; Kuz'mich, V G; Fomichev, A V

2013-12-01

National toxicology school of the Kirov Military Medical Academy, demonstrates the unity of clinical and experimental approaches related to one purpose throughout its history--saving human life and health from exposure to toxic substances of chemical nature. For more than three centuries the russian science of toxicology has been steadily developing, often ahead of the world science. It helped to create the means of protection and develop methods of treatment for chemical lesions. Currently, toxicology departments of military field therapy and military toxicology and medical protection are actively involved in the current study of military medicine, restructuring policy to provide toxicological aid in the Armed Forces, the development and introduction of Innovative methods of diagnosis and treatment of victims of toxicological etiology.

Principles and procedures in forensic toxicology.

Science.gov (United States)

Wyman, John F

2012-09-01

The principles and procedures employed in a modern forensic toxicology lab are detailed in this review. Aspects of Behavioral and Postmortem toxicology, including certification of analysts and accreditation of labs, chain of custody requirements, typical testing services provided, rationale for specimen selection, and principles of quality assurance are discussed. Interpretation of toxicology results in postmortem specimens requires the toxicologist and pathologist to be cognizant of drug-drug interactions, drug polymorphisms and pharmacogenomics, the gross signs of toxic pathology, postmortem redistribution, confirmation of systemic toxicity in suspected overdoses, the possibility of developed tolerance, and the effects of decomposition on drug concentration.

Drug shortages: Implications for medical toxicology.

Science.gov (United States)

Mazer-Amirshahi, Maryann; Hawley, Kristy L; Zocchi, Mark; Fox, Erin; Pines, Jesse M; Nelson, Lewis S

2015-07-01

Drug shortages have significantly increased over the past decade. There are limited data describing how shortages impact medical toxicology of drugs. To characterize drug shortages affecting the management of poisoned patients. Drug shortage data from January 2001 to December 2013 were obtained from the University of Utah Drug Information Service. Shortage data for agents used to treat poisonings were analyzed. Information on drug type, formulation, reason for shortage, shortage duration, marketing, and whether the drug was available from a single source was collected. The availability of a substitute therapy and whether substitutes were in shortage during the study period were also investigated. Of 1,751 shortages, 141 (8.1%) impacted drugs used to treat poisoned patients, and as of December 2013, 21 (14.9%) remained unresolved. New toxicology shortages increased steadily from the mid-2000s, reaching a high of 26 in 2011. Median shortage duration was 164 days (interquartile range: 76-434). Generic drugs were involved in 85.1% of shortages and 41.1% were single-source products. Parenteral formulations were often involved in shortages (89.4%). The most common medications in shortage were sedative/hypnotics (15.6%). An alternative agent was available for 121 (85.8%) drugs; however, 88 (72.7%) alternatives were also affected by shortages at some point during the study period. When present, the most common reasons reported were manufacturing delays (22.0%) and supply/demand issues (17.0%). Shortage reason was not reported for 48.2% of drugs. Toxicology drug shortages are becoming increasingly prevalent, which can result in both suboptimal treatment and medication errors from using less familiar alternatives. Drug shortages affected a substantial number of critical agents used in the management of poisoned patients. Shortages were often of long duration and for drugs without alternatives. Providers caring for poisoned patients should be aware of current shortages and

Capitalist Crisis, Communication, & Culture – Introduction to the Special Issue of tripleC

OpenAIRE

Christian Fuchs; Matthias Schafranek; David Hakken; Marcus Breen

2010-01-01

The worldwide economic downturn is indicative for a new large crisis of capitalism. The future of capitalism is in this situation not determined, but depends on collective human agency. This introduction to the special issue of tripleC on “Capitalist Crisis, Communication & Culture” presents general arguments about the crisis, a general model of the political economy of capitalist communication, and a systematic typology of literature about capitalist crisis & communication. The introduced mo...

The intersection of behavioral genetics and political science: introduction to the special issue.

Science.gov (United States)

Hatemi, Peter K

2012-02-01

The collection of papers in this special edition of Twin Research and Human Genetics represents a major land-mark at the intersection of behavioral genetics and political science. This issue is the fruit of 20 political scientists attending the Behavioral Genetics Association Methods Workshop in Boulder and a hands-on training practicum at the Virginia Institute for Psychiatric and Behavioral Genetics, and includes results from the first wave of political science twin surveys.

Call for Papers – Special issue: Project Management in the Non-Profit Sector

OpenAIRE

Sankaran, Shankar

2015-01-01

This journal special issue will explore diverse stakeholder perspectives and share examples of project management practices in the non-profit sector. Key objectives are to develop understandings of project management practice in the sector, to examine how cross-sectoral collaboration and learning can help non-profit organisations achieve their project and programme objectives, and to explore ways in which the wider project management community can learn from experiences in the non-profit sector.

Advancements in Research on Creativity and Giftedness in Mathematics Education: Introduction to the Special Issue

Science.gov (United States)

Singer, Florence Mihaela; Sheffield, Linda Jensen; Leikin, Roza

2017-01-01

Creativity and giftedness in mathematics education research are topics of an increased interest in the education community during recent years. This introductory paper to the special issue on Mathematical Creativity and Giftedness in Mathematics Education has a twofold purpose: to offer a brief historical perspective on the study of creativity and…

Big data in psychology: Introduction to the special issue.

Science.gov (United States)

Harlow, Lisa L; Oswald, Frederick L

2016-12-01

The introduction to this special issue on psychological research involving big data summarizes the highlights of 10 articles that address a number of important and inspiring perspectives, issues, and applications. Four common themes that emerge in the articles with respect to psychological research conducted in the area of big data are mentioned, including: (a) The benefits of collaboration across disciplines, such as those in the social sciences, applied statistics, and computer science. Doing so assists in grounding big data research in sound theory and practice, as well as in affording effective data retrieval and analysis. (b) Availability of large data sets on Facebook, Twitter, and other social media sites that provide a psychological window into the attitudes and behaviors of a broad spectrum of the population. (c) Identifying, addressing, and being sensitive to ethical considerations when analyzing large data sets gained from public or private sources. (d) The unavoidable necessity of validating predictive models in big data by applying a model developed on 1 dataset to a separate set of data or hold-out sample. Translational abstracts that summarize the articles in very clear and understandable terms are included in Appendix A, and a glossary of terms relevant to big data research discussed in the articles is presented in Appendix B. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

On the history of the quantum. Introduction to the HQ4 special issue

Science.gov (United States)

Navarro, Jaume; Blum, Alexander; Lehner, Christoph

2017-11-01

Eight years ago, a special issue in this journal published a dozen papers with new studies on the history of quantum physics. That issue was an output of a conference in Utrecht one year earlier, the second in a series organized by the then existing large-scale project coordinated by the Max Planck Institute for the History of Science and the Fritz Haber Institute. Since then, that project has produced a number of publications, workshops and other academic outcomes, but more importantly, it triggered the consolidation of an international community of historians and philosophers of science producing novel work on the history of quantum physics. Five years after the third meeting, which took place in Berlin in 2010, many of the scholars from that group and some new ones met for four days in Donostia/San Sebastian for the HQ4 meeting. The time was ripe for new results to be shared and discussed, and this issue collects some of the papers presented at that gathering.

Ventilation in school buildings. Special issue; Ventilatie in schoolgebouwen. Themanummer

Energy Technology Data Exchange (ETDEWEB)

Zeiler, W.; Boxem, G.; Van Bruchem, M.; Smits, E.H.J.; Van Dijken, F. [Technische Universiteit Eindhoven, Eindhoven (Netherlands); Joosten, L.; Clocquet, R. [DHV Bouw en Industrie, Amersfoort (Netherlands); Pernot, C. [TNO Bouw, Delft (Netherlands); Haans, L.; Boerstra, A.C. [BBA Boerstra Binnenmilieu Advies, Rotterdam (Netherlands); Leenaerts, C.L.M.; Donze, G.J. [W/E adviseurs duurzaam bouwen, Gouda (Netherlands); Leysen, L.M. [Astma Fonds, Leusden (Netherlands); Blezer, I.H.W. [Hollman Adviseurs, Venlo (Netherlands); Meester, A.W.J. [Alusta, Natuurlijke Ventilatietechniek, Etten Leur (Netherlands); Bronsema, B. [Faculteit der Bouwkunde, Bronsema Consult, Technische Universiteit Delft, Delft (Netherlands)

2005-10-01

In this special issue one editorial and 9 articles are dedicated to several aspects with regard to ventilation in school buildings: (1) healthy and draught-free ventilation in schools; (2) air quality and comfort in primary schools; (3) preparatory study on the indoor environment in primary schools; (4) options to improve ventilation in school buildings; (5) the relation between the indoor environment in classrooms and the health of students; (6) the activities of the Asthma Fund to create healthy school buildings for children suffering asthma; (7) the necessity of mechanical ventilation in school buildings; (8) demand-controlled ventilation in schools; (9) first experiences with a newly built primary school. [Dutch] In deze speciale aflevering zijn 1 redactioneel artikel en 9 artikelen gewijd aan verschillende aspecten m.b.t. ventilatie in schoolgebouwen: (1) onderzoek naar gezond en tochtvrij ventileren; (2) luchtkwaliteit en comfort op basisscholen: (3) voorstudie binnenmilieu basisscholen; (4) opties om de ventilatie in scholen te verbeteren; (5) de relatie tussen het binnenmilieu in klaslokalen en de gezondheid van studenten; (6) activiteiten van het Astma Fonds voor gezonde schoolgebouwen voor kinderen met astma; (7) de noodzaak voor mechanische ventilatie in schoolgebouwen; (8) vraaggestuurde ventilatie in scholen; (9) de eerste ervaringen in een nieuwe basisschool in Voorschoten.

Toxicological aspects of energy production

International Nuclear Information System (INIS)

Sanders, C.L.

1986-01-01

Part I reviews the principles of toxicology, describes the biological fate of chemicals in the body, discusses basic pathobiology, and reviews short-term toxicity tests. Part II describes the toxicology and pathology of pollutants in several important organ systems. The greatest emphasis is placed on the respiratory tract because of its high probability as a route of exposure to pollutants from energy technologies and its high sensitivity to pollutant related tissue damage. Part III describes the toxicological aspects of specific chemical classes associated with fossil fuels; these include polycyclic hydrocarbons, gases and metals. Part IV describes the biomedical effects associated with each energy technology, including coal and oil, fossil fuel and biomass conversions, solar and geothermal and radiological health aspects associated with uranium mining, nuclear fission and fusion, and with nonionising radiations and electromagnetic fields

A great pioneer of clinical science remembered: introduction to the special issue in honor of Paul E. Meehl.

Science.gov (United States)

Lilienfeld, Scott O; Waller, Niels G

2005-10-01

In this special issue, the seminal contributions to clinical psychology of Paul E. Meehl, who passed away in 2003, are commemorated. The nine articles comprising this special issue chronicle Meehl's remarkable intellectual biography and examine his influence on diverse domains of psychology, including the clinical versus actuarial prediction debate, the cognitive activity of the clinician, personality assessment and trait theory, the etiology of schizophrenia, the shortcomings of statistical significance testing, and the use of metascientific methods to evaluate competing models of human nature. These articles illustrate not only Meehl's legendary brilliance but also his pivotal role in forcing clinical psychologists to think more clearly and incisively about their subject matter. 2005 Wiley Periodicals, Inc.

Research Article Special Issue

African Journals Online (AJOL)

pc

2018-04-16

Apr 16, 2018 ... The dimensions to business process strategy factors are .... Investigation pains directed at further exploring these issues are very ... relationship management, material flow management, corporate culture in SMEs' Customer.

Getting patent policy right: an introduction to a special issue on the European Patent System

DEFF Research Database (Denmark)

Elsmore, Matthew J.

2009-01-01

An editorial on the Special Issue: Dealing with the major questions confronting the basics of the European patent system; plus a look at the possible solutions; includes an overview of the article contributions....

[Research advances in eco-toxicological diagnosis of soil pollution].

Science.gov (United States)

Liu, Feng; Teng, Hong-Hui; Ren, Bai-Xiang; Shi, Shu-Yun

2014-09-01

Soil eco-toxicology provides a theoretical basis for ecological risk assessment of contaminated soils and soil pollution control. Research on eco-toxicological effects and molecular mechanisms of toxic substances in soil environment is the central content of the soil eco-toxicology. Eco-toxicological diagnosis not only gathers all the information of soil pollution, but also provides the overall toxic effects of soil. Therefore, research on the eco-toxicological diagnosis of soil pollution has important theoretical and practical significance. Based on the research of eco-toxicological diagnosis of soil pollution, this paper introduced some common toxicological methods and indicators, with the advantages and disadvantages of various methods discussed. However, conventional biomarkers can only indicate the class of stress, but fail to explain the molecular mechanism of damage or response happened. Biomarkers and molecular diagnostic techniques, which are used to evaluate toxicity of contaminated soil, can explore deeply detoxification mechanisms of organisms under exogenous stress. In this paper, these biomarkers and techniques were introduced systematically, and the future research trends were prospected.

Post-mortem toxicology in young sudden cardiac death victims

DEFF Research Database (Denmark)

Bjune, Thea; Risgaard, Bjarke; Kruckow, Line

2017-01-01

Aims: Several drugs increase the risk of ventricular fibrillation and sudden cardiac death (SCD). We aimed to investigate in detail the toxicological findings of all young SCD throughout Denmark. Methods and results: Deaths in persons aged 1-49 years were included over a 10-year period. Death...... certificates and autopsy reports were retrieved and read to identify cases of sudden death and establish cause of death. All medico-legal autopsied SCD were included and toxicological reports collected. Positive toxicology was defined as the presence of any substance (licit and/or illicit). All toxicological...... findings had previously been evaluated not to have caused the death (i.e. lethal concentrations were excluded). We identified 620 medico-legal autopsied cases of SCD, of which 77% (n = 477) were toxicologically investigated post-mortem, and 57% (n = 270) had a positive toxicology profile. Sudden cardiac...

[Preface for special issue on bio-based materials (2016)].

Science.gov (United States)

Weng, Yunxuan

2016-06-25

Bio-based materials are new materials or chemicals with renewable biomass as raw materials such as grain, legume, straw, bamboo and wood powder. This class of materials includes bio-based polymer, biobased fiber, glycotechnology products, biobased rubber and plastics produced by biomass thermoplastic processing and basic biobased chemicals, for instance, bio-alcohols, organic acids, alkanes, and alkenes, obtained by bio-synthesis, bio-processing and bio-refinery. Owing to its environmental friendly and resource conservation, bio-based materials are becoming a new dominant industry taking the lead in the world scientific and technological innovation and economic development. An overview of bio-based materials development is reported in this special issue, and the industrial status and research progress of the following aspects, including biobased fiber, polyhydroxyalkanoates, biodegradable mulching film, bio-based polyamide, protein based biomedical materials, bio-based polyurethane, and modification and processing of poly(lactic acid), are introduced.

Behavioral assays in environmental toxicology

Energy Technology Data Exchange (ETDEWEB)

Weiss, B.

1979-01-01

Environmental toxicology is too permeated by questions about how the whole organism functions to abandon intact animals as test systems. Behavior does not participate as a single entity or discipline. It ranges across the total spectrum of functional toxicity, from tenuous subjective complaints to subtle sensory and motor disturbances demanding advanced instrumentation for their evaluation. Three facets of behavioral toxicology that illustrate its breadth of interests and potential contributions are discussed.

Systems Toxicology: Real World Applications and Opportunities

Science.gov (United States)

2017-01-01

Systems Toxicology aims to change the basis of how adverse biological effects of xenobiotics are characterized from empirical end points to describing modes of action as adverse outcome pathways and perturbed networks. Toward this aim, Systems Toxicology entails the integration of in vitro and in vivo toxicity data with computational modeling. This evolving approach depends critically on data reliability and relevance, which in turn depends on the quality of experimental models and bioanalysis techniques used to generate toxicological data. Systems Toxicology involves the use of large-scale data streams (“big data”), such as those derived from omics measurements that require computational means for obtaining informative results. Thus, integrative analysis of multiple molecular measurements, particularly acquired by omics strategies, is a key approach in Systems Toxicology. In recent years, there have been significant advances centered on in vitro test systems and bioanalytical strategies, yet a frontier challenge concerns linking observed network perturbations to phenotypes, which will require understanding pathways and networks that give rise to adverse responses. This summary perspective from a 2016 Systems Toxicology meeting, an international conference held in the Alps of Switzerland, describes the limitations and opportunities of selected emerging applications in this rapidly advancing field. Systems Toxicology aims to change the basis of how adverse biological effects of xenobiotics are characterized, from empirical end points to pathways of toxicity. This requires the integration of in vitro and in vivo data with computational modeling. Test systems and bioanalytical technologies have made significant advances, but ensuring data reliability and relevance is an ongoing concern. The major challenge facing the new pathway approach is determining how to link observed network perturbations to phenotypic toxicity. PMID:28362102

Systems Toxicology: Real World Applications and Opportunities.

Science.gov (United States)

Hartung, Thomas; FitzGerald, Rex E; Jennings, Paul; Mirams, Gary R; Peitsch, Manuel C; Rostami-Hodjegan, Amin; Shah, Imran; Wilks, Martin F; Sturla, Shana J

2017-04-17

Systems Toxicology aims to change the basis of how adverse biological effects of xenobiotics are characterized from empirical end points to describing modes of action as adverse outcome pathways and perturbed networks. Toward this aim, Systems Toxicology entails the integration of in vitro and in vivo toxicity data with computational modeling. This evolving approach depends critically on data reliability and relevance, which in turn depends on the quality of experimental models and bioanalysis techniques used to generate toxicological data. Systems Toxicology involves the use of large-scale data streams ("big data"), such as those derived from omics measurements that require computational means for obtaining informative results. Thus, integrative analysis of multiple molecular measurements, particularly acquired by omics strategies, is a key approach in Systems Toxicology. In recent years, there have been significant advances centered on in vitro test systems and bioanalytical strategies, yet a frontier challenge concerns linking observed network perturbations to phenotypes, which will require understanding pathways and networks that give rise to adverse responses. This summary perspective from a 2016 Systems Toxicology meeting, an international conference held in the Alps of Switzerland, describes the limitations and opportunities of selected emerging applications in this rapidly advancing field. Systems Toxicology aims to change the basis of how adverse biological effects of xenobiotics are characterized, from empirical end points to pathways of toxicity. This requires the integration of in vitro and in vivo data with computational modeling. Test systems and bioanalytical technologies have made significant advances, but ensuring data reliability and relevance is an ongoing concern. The major challenge facing the new pathway approach is determining how to link observed network perturbations to phenotypic toxicity.

42 CFR 493.845 - Standard; Toxicology.

Science.gov (United States)

2010-10-01

... 42 Public Health 5 2010-10-01 2010-10-01 false Standard; Toxicology. 493.845 Section 493.845 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES... These Tests § 493.845 Standard; Toxicology. (a) Failure to attain a score of at least 80 percent of...

Research Article Special Issue

African Journals Online (AJOL)

2016-07-16

Jul 16, 2016 ... investigated and analyzed from various library and documentary ... It is therefore evident that applied research on issues related to ...... [29] Cutter-SL., Burton-CG., Emrich-CT., Disaster resilience indicators for benchmarking.

New Trends and Directions in Ethnic Identity among Internationally Transracially Adopted Persons: Summary of Special Issue

Science.gov (United States)

Rosnati, Rosa; Pinderhughes, Ellen E.; Baden, Amanda L.; Grotevant, Harold D.; Lee, Richard M.; Mohanty, Jayashree

2015-01-01

The collective findings of the six articles in this special issue highlight the importance of ethnic-racial socialization and ethnic identity among international transracial adoptees (ITRAs). A multidimensional developmental phenomenon, ethnic identity intersects with other identities, notably adoptive identity. Family, peers, community, and host…

Journal of Transdisciplinary Environmental Studies : Special Issue on The Importance of Local Knowledge and Interdisciplinary Research

DEFF Research Database (Denmark)

For this special issue of TES we have selected four articles on constraints and options for managing trees in Africa. The articles have been produced within a larger multidisciplinary research programme on People, Trees and Agriculture in Africa (Petrea) funded by the Danish Development Research ...

Research Article Special Issue

African Journals Online (AJOL)

pc

2017-11-10

Nov 10, 2017 ... 1Faculty of Sports Science and Coaching, Universiti Pendidikan ... face obesity issues because of several factors such as changes in diet intake, lifestyle, physical ...... and its implications for policy and intervention strategies.

Research Article Special Issue

African Journals Online (AJOL)

pc

2018-02-24

Feb 24, 2018 ... ABSTRACT. Electronic Records and Information Management (e-RIM) framework is paramount for ..... RIM issues and problems that led to information crisis. On the other .... Malaysia: A case study in one government agency”.

Building Management Systems and Domotics. Special issue; Gebouwautomatisering en Domotica. Special

Energy Technology Data Exchange (ETDEWEB)

Rigter, L.; Dekker, P.; Knipscheer, R.; Veenema, R.; Vlietstra, E. [Siemens Building Technologies, Zuerich (Switzerland); Symanczik, H.; Van Houwelingen, P. [Kieback en Peter Nederland, Nunspeet (Netherlands); Van Grieken, K. [Priva Building Intelligence, Delft (Netherlands); De Koning, G. [Regel Partners, Hoevelaken (Netherlands); Hitzert, L.A. [Honeywell, Amsterdam (Netherlands); Uythof, B.H. [Domotica Platform Nederland, Amsterdam (Netherlands); Wortel, W. [Kropman, Rijswijk (Netherlands); Zeiler, W. [Faculteit Bouwkunde - FAGO, Technische Universiteit Eindhoven, Eindhoven (Netherlands); Kamphuis, I.G. [Energieonderzoek Centrum Nederland ECN, Petten (Netherlands); Akkermans, J.M. [Vrije Universiteit, Amsterdam (Netherlands)

2002-05-01

In 12 articles an overview is given of developments in the use of automation and domotics in different types of buildings. Previous specials on the same subject in this magazine were published in november 1989, november 1995 and december 1999. [Dutch] In 12 artikelen wordt uitgebreid aandacht besteed aan ontwikkelingen in gebouwautomatisering en domotica. Eerdere specials over dit onderwerp werden uitgebracht in november 1989, november 1995 en december 1999.

Toxicological Implications of Released Particulate Matter during Thermal Decomposition of Nano-Enabled Thermoplastics.

Science.gov (United States)

Watson-Wright, Christa; Singh, Dilpreet; Demokritou, Philip

2017-01-01

Nano-enabled thermoplastics are part of the growing market of nano-enabled products (NEPs) that have vast utility in several industries and consumer goods. The use and disposal of NEPs at their end of life has raised concerns about the potential release of constituent engineered nanomaterials (ENMs) during thermal decomposition and their impact on environmental health and safety. To investigate this issue, industrially relevant nano-enabled thermoplastics including polyurethane, polycarbonate, and polypropylene containing carbon nanotubes (0.1 and 3% w/v, respectively), polyethylene containing nanoscale iron oxide (5% w/v), and ethylene vinyl acetate containing nanoscale titania (2 and 5% w/v) along with their pure thermoplastic matrices were thermally decomposed using the recently developed lab based Integrated Exposure Generation System (INEXS). The life cycle released particulate matter (called LCPM) was monitored using real time instrumentation, size fractionated, sampled, extracted and prepared for toxicological analysis using primary small airway epithelial cells to assess potential toxicological effects. Various cellular assays were used to assess reactive oxygen species and total glutathione as measurements of oxidative stress along with mitochondrial function, cellular viability, and DNA damage. By comparing toxicological profiles of LCPM released from polymer only (control) with nano-enabled LCPM, potential nanofiller effects due to the use of ENMs were determined. We observed associations between NEP properties such as the percent nanofiller loading, host matrix, and nanofiller chemical composition and the physico-chemical properties of released LCPM, which were linked to biological outcomes. More specifically, an increase in percent nanofiller loading promoted a toxicological response independent of increasing LCPM dose. Importantly, differences in host matrix and nanofiller composition were shown to enhance biological activity and toxicity of LCPM

Research Article Special Issue

African Journals Online (AJOL)

2016-05-15

May 15, 2016 ... Assistant professor, Khorasgan Branch, Islamic Azad University, Isfahan, Iran ... Discussing the issue of knowledge leads inevitably to the problem of beliefs because .... the level of definition from truth at the level of examples.

Research Article Special Issue

African Journals Online (AJOL)

pc

2018-04-18

Apr 18, 2018 ... selectivity of possible lead compounds prior to clinical trials and ... These computational algorithms had resolved previous issues and .... In similarity with the spatial space degree of the universe, these descriptors are running ...

Translational toxicology: a developmental focus for integrated research strategies.

Science.gov (United States)

Hughes, Claude; Waters, Michael; Allen, David; Obasanjo, Iyabo

2013-09-30

Given that toxicology studies the potential adverse effects of environmental exposures on various forms of life and that clinical toxicology typically focuses on human health effects, what can and should the relatively new term of "translational toxicology" be taken to mean? Our assertion is that the core concept of translational toxicology must incorporate existing principles of toxicology and epidemiology, but be driven by the aim of developing safe and effective interventions beyond simple reduction or avoidance of exposure to prevent, mitigate or reverse adverse human health effects of exposures.The field of toxicology has now reached a point where advances in multiple areas of biomedical research and information technologies empower us to make fundamental transitions in directly impacting human health. Translational toxicology must encompass four action elements as follows: 1) Assessing human exposures in critical windows across the lifespan; 2) Defining modes of action and relevance of data from animal models; 3) Use of mathematical models to develop plausible predictions as the basis for: 4) Protective and restorative human health interventions. The discussion focuses on the critical window of in-utero development. Exposure assessment, basic toxicology and development of certain categories of mathematical models are not new areas of research; however overtly integrating these in order to conceive, assess and validate effective interventions to mitigate or reverse adverse effects of environmental exposures is our novel opportunity. This is what we should do in translational toxicology so that we have a portfolio of interventional options to improve human health that include both minimizing exposures and specific preventative/restorative/mitigative therapeutics.

Research Article Special Issue

African Journals Online (AJOL)

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2018-02-01

Feb 1, 2018 ... The main goal of this article is to analyze methodological issues in .... methodology and theory and historiology (theory of historic process) whose goal is to .... internal branches of sociology and interdisciplinary links of ...

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2018-03-22

Mar 22, 2018 ... rameter of computation time and convergence rate. The two scheme have shown ... matrix and its inversion repeatedly for every iteration. This issue causes long ..... Some New Findings on Gauss-Seidel. Technique for Load ...

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African Journals Online (AJOL)

2017-02-15

Feb 15, 2017 ... One of the important issues in the field of human education is the method of ... Encouragement and punishment method in Islamic management has been ... Concept of education refers to the cultivating human talent, this.

Mass Spectrometry Applications for Toxicology

OpenAIRE

Mbughuni, Michael M.; Jannetto, Paul J.; Langman, Loralie J.

2016-01-01

Toxicology is a multidisciplinary study of poisons, aimed to correlate the quantitative and qualitative relationships between poisons and their physiological and behavioural effects in living systems. Other key aspects of toxicology focus on elucidation of the mechanisms of action of poisons and development of remedies and treatment plans for associated toxic effects. In these endeavours, Mass spectrometry (MS) has become a powerful analytical technique with a wide range of application used i...

Inhalation Toxicology Research Institute annual report, October 1, 1994--September 30, 1995

International Nuclear Information System (INIS)

Bice, D.E.; Hahn, F.F.; Hoover, M.D.; Neft, R.E.; Thornton-Manning, J.R.; Bradley, P.L.

1995-12-01

The mission of the Inhalation Toxicology Research Institute (ITRI) is to conduct basic and applied research to improve the understanding of the nature and magnitude of the human health impacts of inhaling airborne materials in the home, workplace, and general environment. Institute research programs have a strong basic science orientation with emphasis on the nature and behavior of airborne materials, the fundamental biology of the respiratory tract, the fate of inhaled materials and the mechanisms by which they cause disease, and the means by which data produced in the laboratory can be used to estimate risks to human health. Disorders of the respiratory tract continue to be a major health concern, and inhaled toxicants are thought to contribute substantially to respiratory morbidity. As the largest laboratory dedicated to the study of basic inhalation toxicology, ITRI provides a national resource of specialized facilities, personnel, and educational activities serving the needs of government, academia, and industry. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database

Inhalation Toxicology Research Institute annual report, October 1, 1994--September 30, 1995

Energy Technology Data Exchange (ETDEWEB)

Bice, D.E.; Hahn, F.F.; Hoover, M.D.; Neft, R.E.; Thornton-Manning, J.R.; Bradley, P.L. [eds.

1995-12-01

The mission of the Inhalation Toxicology Research Institute (ITRI) is to conduct basic and applied research to improve the understanding of the nature and magnitude of the human health impacts of inhaling airborne materials in the home, workplace, and general environment. Institute research programs have a strong basic science orientation with emphasis on the nature and behavior of airborne materials, the fundamental biology of the respiratory tract, the fate of inhaled materials and the mechanisms by which they cause disease, and the means by which data produced in the laboratory can be used to estimate risks to human health. Disorders of the respiratory tract continue to be a major health concern, and inhaled toxicants are thought to contribute substantially to respiratory morbidity. As the largest laboratory dedicated to the study of basic inhalation toxicology, ITRI provides a national resource of specialized facilities, personnel, and educational activities serving the needs of government, academia, and industry. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

Research Article Special Issue

African Journals Online (AJOL)

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2018-05-16

May 16, 2018 ... This paper discusses the issues and challenges faced during .... provision of this AELF's office is costly and need permission from the university's management. .... This is to deduct weeks for the assignment and tests because ...

IRIS Toxicological Review of Acrolein (2003 Final)

Science.gov (United States)

EPA announced the release of the final report, Toxicological Review of Acrolein: in support of the Integrated Risk Information System (IRIS). The updated Summary for Acrolein and accompanying toxicological review have been added to the IRIS Database.

14 CFR 21.190 - Issue of a special airworthiness certificate for a light-sport category aircraft.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Issue of a special airworthiness... consensus standard used; (2) State that the aircraft meets the provisions of the identified consensus... quality assurance system that meets the identified consensus standard; (4) State that the manufacturer...

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2017-10-05

Oct 5, 2017 ... ources and Food Industry, Universiti Sultan ZainalAbidin, 22200 Besut, ... ty problem has become a major issue in Malaysia for the past two decade ... pollution can be defined as contamination of the indoor or outdoor ...

Evaluating SGLT2 inhibitors for type 2 diabetes: pharmacokinetic and toxicological considerations.

Science.gov (United States)

Scheen, André J

2014-05-01

Inhibitors of sodium-glucose cotransporters type 2 (SGLT2), which increase urinary glucose excretion independently of insulin, are proposed as a novel approach for the management of type 2 diabetes mellitus (T2DM). An extensive literature search was performed to analyze the pharmacokinetic characteristics, toxicological issues and safety concerns of SGLT2 inhibitors in humans. This review focuses on three compounds (dapagliflozin, canagliflozin, empagliflozin) with results obtained in healthy volunteers (including drug-drug interactions), patients with T2DM (single dose and multiple doses) and special populations (those with renal or hepatic impairment). The three pharmacological agents share an excellent oral bioavailability, long half-life allowing once-daily administration, low accumulation index and renal clearance, the absence of active metabolites and a limited propensity to drug-drug interactions. No clinically relevant changes in pharmacokinetic parameters were observed in T2DM patients or in patients with mild/moderate renal or hepatic impairment. Adverse events are a slightly increased incidence of mycotic genital and rare benign urinary infections. SGLT2 inhibitors have the potential to reduce several cardiovascular risk factors, and cardiovascular outcome trials are currently ongoing. The best positioning of SGLT2 inhibitors in the armamentarium for treating T2DM is still a matter of debate.

Special Issue “Recent Synthetic Aspects on the Chemistry of Nitro, Nitroso and Amino Compounds”

OpenAIRE

Alessandro Palmieri

2016-01-01

Nitrogen-containing molecules are key scaffolds that are widely applied in organic synthesis as precursors of highly functionalized materials, and are also investigated for their biological activities. This Special Issue collects seven innovative contributions which expand our knowledge of the chemistry of nitro compounds, amines, diazonium salts, and peptides, and that provide a good overview about their main reactivities.

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2018-05-01

May 1, 2018 ... stability is a very good issue of the power systems resilience to the high disturbances. In this paper, a mirror-fuzzy controller scaled by PSO has been proposed ... In many system analysis, the researchers have configured the ...

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2018-03-07

Mar 7, 2018 ... ethical issues behind the retrieval of organs (commitment to ... The article reviews the practices of European countries and attitude of the EU citizens to the .... knowledge that the purchase and sale of donor organs is prohibited ...

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2017-11-24

Nov 24, 2017 ... FEDERAL UNIVERSITY (FROM EMOTIONAL EDUCATION TO GLOBAL. THINKING ... ANNOTATION. The article highlights the topical issues of human education of the future humanistic- ... conditions (continuous self-education, updating and integration of educational resources on the basis of the ...

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2018-03-22

Mar 22, 2018 ... Voltage decay is an important issue in the power system community. ... of voltage profile, the total real power loss in the system is also determined to ..... Kumar A. Optimal placement of DG in radial distribution systems based.

Assessing the scientific research productivity of a leading toxicology journal: A case study of Human & Experimental Toxicology from 2003 to 2012.

Science.gov (United States)

Zyoud, Sa'ed H; Al-Jabi, Samah W; Sweileh, Waleed M; Awang, Rahmat

2014-01-01

Bibliometric studies are increasingly being used for research assessments. Bibliometric indicators involve the application of statistical methods to scientific publications to obtain the bibliographics for each journal. The main objective of this study was to conduct a bibliometric evaluation of Human & Experimental Toxicology retrieved from the Scopus database. This study obtained data from Scopus published from 1 January 2003 till 31 December 2012. The keywords entered in Scopus to accomplish the objective of this study were 'Human', 'Experimental' and 'Toxicology' as 'Source Title'. Research productivity was evaluated based on a methodology developed and used in other bibliometric studies by analysing (a) total and trends in Human & Experimental Toxicology contributions in research between 2003 and 2012; (b) Human & Experimental Toxicology authorship patterns and productivity; (c) collaboration patterns; and (d) the citations received by the publications. There were 1229 research articles published in Human & Experimental Toxicology. Of the articles included, 947 (77.1%) were original articles and 104 (8.5%) were review articles. The Hirsch-index of the retrieved documents was 35. The largest number of publications in Human & Experimental Toxicology was from the United States (19.6%), followed by India (12.8%) and Turkey (10.9%). The total number of citations was 9119, with a median (interquartile range) of 3 (1-9) in 6797 documents. The highest median (interquartile range) number of citations was 8 (2.7-12.7) for France, followed by 7.5 (2-22.5) for Iran and 6 (3-13.5) for the United Kingdom. The country most often citing articles that were published in Human & Experimental Toxicology was the United States, which made citations in 1508 documents, followed by India with citations in 792 documents. The documents in Human & Experimental Toxicology focus principally on original data, with very few review articles. Review articles tend to have higher citation rates

Handbook of safety assessment of nanomaterials from toxicological testing to personalized medicine

CERN Document Server

Fadeel, Bengt

2014-01-01

"The Handbook of Safety Assessment of Nanomaterials: From Toxicological Testing to Personalized Medicine provides a comprehensive overview of the state of the art of nanotoxicology and is a unique resource that fills up many knowledge gaps in the toxicity issue of nanomaterials in medical applications. The book is distinguished by up-to-date insights into creating a science-based framework for safety assessment of nanomedicines." -Prof. Yuliang Zhao, National Center for Nanosciences and Technology, China.

Research Article Special Issue

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2018-03-07

Mar 7, 2018 ... in the development of more up-to-date urban space. ... The goal of this paper is to analyze the issues of the organization of urban environment in ... The model of transport less micro-district Nebo (ACADEMIA gallery), the ...

CSR communication: Quo vadis? A systematic review of the literature and introduction to the special issue

NARCIS (Netherlands)

Golob, U.; Elving, W.; Thomsen, C.; Podnar, K.; Nielsen, A.; Schultz, F.

2013-01-01

This paper aims to introduce the special issue on CSR communication attached to the First International CSR Communication Conference held in Amsterdam in October 2011. The aim of the introduction is also to review CSR communication papers published in scholarly journals in order to make a summary of

A process of change and a changing process : introduction to the special issue on contemporary gentrification

NARCIS (Netherlands)

Doucet, B.

2014-01-01

Gentrification is a process of social and spatial change, but it is also a changing process. This special issue aims to better understand new forms of gentrification, policies and experiences which have emerged since the year 2000. Specific emphasis has been given to the Netherlands, a country where

Research Article Special Issue

African Journals Online (AJOL)

2016-05-15

May 15, 2016 ... Journal of Fundamental and Applied Sciences is licensed under a Creative ... 1. Faculty of Engineering, Civil Engineering Department, Urmia Branch, ..... Table 4. Sections of the main components of 16 stories building ..... International Journal of Engineering Science and Innovative ... Issue 1, January 2013.

Historical perspectives on cadmium toxicology

International Nuclear Information System (INIS)

Nordberg, Gunnar F.

2009-01-01

The first health effects of cadmium (Cd) were reported already in 1858. Respiratory and gastrointestinal symptoms occurred among persons using Cd-containing polishing agent. The first experimental toxicological studies are from 1919. Bone effects and proteinuria in humans were reported in the 1940's. After World War II, a bone disease with fractures and severe pain, the itai-itai disease, a form of Cd-induced renal osteomalacia, was identified in Japan. Subsequently, the toxicokinetics and toxicodynamics of Cd were described including its binding to the protein metallothionein. International warnings of health risks from Cd-pollution were issued in the 1970's. Reproductive and carcinogenic effects were studied at an early stage, but a quantitative assessment of these effects in humans is still subject to considerable uncertainty. The World Health Organization in its International Program on Chemical Safety, WHO/IPCS (1992) (Cadmium. Environmental Health Criteria Document 134, IPCS. WHO, Geneva, 1-280.) identified renal dysfunction as the critical effect and a crude quantitative evaluation was presented. In the 1990's and 2000 several epidemiological studies have reported adverse health effects, sometimes at low environmental exposures to Cd, in population groups in Japan, China, Europe and USA (reviewed in other contributions to the present volume). The early identification of an important role of metallothionein in cadmium toxicology formed the basis for recent studies using biomarkers of susceptibility to development of Cd-related renal dysfunction such as gene expression of metallothionein in peripheral lymphocytes and autoantibodies against metallothionein in blood plasma. Findings in these studies indicate that very low exposure levels to cadmium may give rise to renal dysfunction among sensitive subgroups of human populations such as persons with diabetes.

Inhalation Toxicology Research Institute. Annual report, October 1, 1978-September 30, 1979

International Nuclear Information System (INIS)

Henderson, R.F.; Diel, J.H.; Martinez, B.S.

1979-12-01

Research information is given by the annual report from the Inhalation Toxicology Research Institute with abstracts for each of the 109 papers. Major sections of interest are nuclear energy toxicology, solar energy toxicology, diesel technology toxicology, coal technology toxicology, and conservation technology toxicology. Also included are seven appendices covering publications of technical reports and publications in open literature, abstracts publications in the open literature, seminars presented by visiting scientists and presentations before scientific meetings, organization of the Inhalation Toxicology Research Institute, and the status of experiments using beagle dogs

Systems Toxicology: From Basic Research to Risk Assessment

Science.gov (United States)

2014-01-01

Systems Toxicology is the integration of classical toxicology with quantitative analysis of large networks of molecular and functional changes occurring across multiple levels of biological organization. Society demands increasingly close scrutiny of the potential health risks associated with exposure to chemicals present in our everyday life, leading to an increasing need for more predictive and accurate risk-assessment approaches. Developing such approaches requires a detailed mechanistic understanding of the ways in which xenobiotic substances perturb biological systems and lead to adverse outcomes. Thus, Systems Toxicology approaches offer modern strategies for gaining such mechanistic knowledge by combining advanced analytical and computational tools. Furthermore, Systems Toxicology is a means for the identification and application of biomarkers for improved safety assessments. In Systems Toxicology, quantitative systems-wide molecular changes in the context of an exposure are measured, and a causal chain of molecular events linking exposures with adverse outcomes (i.e., functional and apical end points) is deciphered. Mathematical models are then built to describe these processes in a quantitative manner. The integrated data analysis leads to the identification of how biological networks are perturbed by the exposure and enables the development of predictive mathematical models of toxicological processes. This perspective integrates current knowledge regarding bioanalytical approaches, computational analysis, and the potential for improved risk assessment. PMID:24446777

La toxicología en la Universidad de Sevilla

OpenAIRE

Puerto Rodríguez, María; Cameán Fernández, Ana María; Moreno Navarro, Isabel María; Pichardo Sánchez, Silvia; Prieto Ortega, Ana Isabel; Jos Gallego, Ángeles Mencía

2010-01-01

La docencia del Área de Toxicología en la Universidad de Sevilla se desarrolla en la actualidad en dos titulaciones, Farmacia y Bioquímica. En los planes de estudios actuales la carga lectiva del Área viene dada por las asignaturas de Toxicología (asignatura troncal), y Toxicología Alimentaria (asignatura optativa) en la Licenciatura de Farmacia, y de Toxicología Molecular (asignatura optativa) en la Licenciatura de Bioquímica. Una vez aprobados por la Agencia Nacional de la Evaluación de la ...

Ventilation systems in houses. Special issue; Woonhuisventilatie. Special

Energy Technology Data Exchange (ETDEWEB)

Op ' t Veld, P.; Van der Aa, A. [Cauberg-Huygen Raadgevend Ingenieurs, Rotterdam (Netherlands); Verschoor, M.J.E. [Afdeling Koudetechniek en Warmtepompen, TNO Milieu, Energie en Procesinnovatie TNO-MEP, Apeldoorn (Netherlands); Van Gulik, L.H. [Itho, Scheidam (Netherlands); Van der Mark, K.; Overman, P. [AGPO, Breda (Netherlands); Roemer, J.C.; Schuitema, R. [ECN Duurzame Energie in de Gebouwde Omgeving DEGO, Petten (Netherlands); Weterings, M. [GGD voor Rotterdam e.o., Rotterdam (Netherlands); Rosenmai, T.; Rasmussen, S. [Copenhagen Business School, Copenhagen (Denmark); Vollebregt, R. [Bureau Kent, Utrecht (Netherlands); Smeets, L.J.M. [Nederlandse onderneming voor energie en milieu Novem, Utrecht (Netherlands)

2001-06-01

In 10 articles attention is paid to several aspects with respect to ventilation of houses. This issue includes an overview of suppliers of high-efficiency heat recovering balanced ventilation systems.

Space Toxicology: Human Health during Space Operations

Science.gov (United States)

Khan-Mayberry, Noreen; James, John T.; Tyl, ROchelle; Lam, Chiu-Wing

2010-01-01

Space Toxicology is a unique and targeted discipline for spaceflight, space habitation and occupation of celestial bodies including planets, moons and asteroids. Astronaut explorers face distinctive health challenges and limited resources for rescue and medical care during space operation. A central goal of space toxicology is to protect the health of the astronaut by assessing potential chemical exposures during spaceflight and setting safe limits that will protect the astronaut against chemical exposures, in a physiologically altered state. In order to maintain sustained occupation in space on the International Space Station (ISS), toxicological risks must be assessed and managed within the context of isolation continuous exposures, reuse of air and water, limited rescue options, and the need to use highly toxic compounds for propulsion. As we begin to explore other celestial bodies in situ toxicological risks, such as inhalation of reactive mineral dusts, must also be managed.

Techniques for Investigating Molecular Toxicology of Nanomaterials.

Science.gov (United States)

Wang, Yanli; Li, Chenchen; Yao, Chenjie; Ding, Lin; Lei, Zhendong; Wu, Minghong

2016-06-01

Nanotechnology has been a rapidly developing field in the past few decades, resulting in the more and more exposure of nanomaterials to human. The increased applications of nanomaterials for industrial, commercial and life purposes, such as fillers, catalysts, semiconductors, paints, cosmetic additives and drug carriers, have caused both obvious and potential impacts on human health and environment. Nanotoxicology is used to study the safety of nanomaterials and has grown at the historic moment. Molecular toxicology is a new subdiscipline to study the interactions and impacts of materials at the molecular level. To better understand the relationship between the molecular toxicology and nanomaterials, this review summarizes the typical techniques and methods in molecular toxicology which are applied when investigating the toxicology of nanomaterials and include six categories: namely; genetic mutation detection, gene expression analysis, DNA damage detection, chromosomal aberration analysis, proteomics, and metabolomics. Each category involves several experimental techniques and methods.

Research Article Special Issue

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2018-03-07

Mar 7, 2018 ... nology Management and Technopreneurship, Universiti Teknikal Mal .... development of SMEs which are recession, global sourcing, lack of ..... issues act as barriers to export which are product quality, logistics and shipping, ... may influenced on the supply chain of payment and the operation cost itself.

[Forensic medicine as the cradle of toxicology in Russia].

Science.gov (United States)

Popov, V L; Grebeniuk, A N; Pigolkin, Iu I; Tolmachev, I A; Bozhchenko, A P; Timoshevskiĭ, A A

2013-01-01

Modern toxicology as a science and educational subject originated from forensic medicine in the middle of the XIXth century. In the beginning, selected toxicological problems were taught in the Emperor's Medical Surgical Academy (presently S.M. Kirov Military Medical Academy, Sankt-Peterburg) and at the Medical Faculty of the Moscow University (presently I.M. Sechenov First Moscow State Medical University, Moscow). The greatest contribution to the development of toxicology was made by such outstanding scientists as professors S.A. Gromov, P.P. Pelekhin, P.P. Zablotsky-Desyatovsky, E.V. Pelikan, Ya.A. Chistovich, G.I. Blosfel'd, I.M. Sorokin, D.P. Kosorotov, A.V. Grigoriev, V.V. Andreev, A.A. Glebovich, A.N. Grigoriev, B.I. Predtechensky, V.M. Rozhkov, S.S. Vail, M.N. Lubotsky, etc. The works of these researchers predetermined the further development of toxicology in this country, its main purpose being provision of medical aid in case of poisoning and diseases of chemical etiology. Another line of toxicological research became industrial and environmental toxicology having the purpose of hygienic rating and prevention of poisoning. Nevertheless, all aspects of the multifaceted science of toxicology are related to forensic medicine as the cradle in which it originated, evolved, and turned into a self-consistent science.

A special issue of the Journal of Forestry---proceedings of the 2013 National Silviculture Workshop

Science.gov (United States)

James M. Guldin; Marilyn A. Buford

2014-01-01

This special issue of the Journal of Forestry presents the Proceedings of the 2013 National Silviculture Workshop (NSW), which was held as one of the concurrent sessions of the 2013 national convention of the Society of American Foresters (SAF) and sponsored by the D-2 Silviculture Working Group. This marks the first time the NSW has been held in conjunction with the...

Special Issue “Recent Synthetic Aspects on the Chemistry of Nitro, Nitroso and Amino Compounds”

Directory of Open Access Journals (Sweden)

Alessandro Palmieri

2016-12-01

Full Text Available Nitrogen-containing molecules are key scaffolds that are widely applied in organic synthesis as precursors of highly functionalized materials, and are also investigated for their biological activities. This Special Issue collects seven innovative contributions which expand our knowledge of the chemistry of nitro compounds, amines, diazonium salts, and peptides, and that provide a good overview about their main reactivities.

Research Article Special Issue

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2018-03-07

Mar 7, 2018 ... technological innovations and the spread of knowledge. ... In this paper, we propose a conceptual model to search relevant scientific ... The digital libraries are becoming a source for discovering new research trends ... Text mining techniques are used to solve some particular business issues, so it is called.

Research Article Special Issue

African Journals Online (AJOL)

2016-05-15

May 15, 2016 ... ABSTRACT. In megacities, exposure to high concentrations of air pollution, as a major concern on public health, is being felt worldwide problem. The issue of particulate matter especially the PM2.5 has become extremely crucial in Tehran, due to industrialization and population growth. Therefore, it.

Naval Medical Research and Development News. Volume 8, Issue 1, January 2016

Science.gov (United States)

2016-01-01

exposure routes with a specialization in inhalation . In vitro toxicology uses animal and human cells lines and tissue models. Emerging approaches in...like Passed Assistant Surgeon I. Franklin Cohn, USN, outlined the deleterious effects of gasoline fumes, the risk of carbon monoxide poisoning

OpenTox predictive toxicology framework: toxicological ontology and semantic media wiki-based OpenToxipedia.

Science.gov (United States)

Tcheremenskaia, Olga; Benigni, Romualdo; Nikolova, Ivelina; Jeliazkova, Nina; Escher, Sylvia E; Batke, Monika; Baier, Thomas; Poroikov, Vladimir; Lagunin, Alexey; Rautenberg, Micha; Hardy, Barry

2012-04-24

The OpenTox Framework, developed by the partners in the OpenTox project (http://www.opentox.org), aims at providing a unified access to toxicity data, predictive models and validation procedures. Interoperability of resources is achieved using a common information model, based on the OpenTox ontologies, describing predictive algorithms, models and toxicity data. As toxicological data may come from different, heterogeneous sources, a deployed ontology, unifying the terminology and the resources, is critical for the rational and reliable organization of the data, and its automatic processing. The following related ontologies have been developed for OpenTox: a) Toxicological ontology - listing the toxicological endpoints; b) Organs system and Effects ontology - addressing organs, targets/examinations and effects observed in in vivo studies; c) ToxML ontology - representing semi-automatic conversion of the ToxML schema; d) OpenTox ontology- representation of OpenTox framework components: chemical compounds, datasets, types of algorithms, models and validation web services; e) ToxLink-ToxCast assays ontology and f) OpenToxipedia community knowledge resource on toxicology terminology.OpenTox components are made available through standardized REST web services, where every compound, data set, and predictive method has a unique resolvable address (URI), used to retrieve its Resource Description Framework (RDF) representation, or to initiate the associated calculations and generate new RDF-based resources.The services support the integration of toxicity and chemical data from various sources, the generation and validation of computer models for toxic effects, seamless integration of new algorithms and scientifically sound validation routines and provide a flexible framework, which allows building arbitrary number of applications, tailored to solving different problems by end users (e.g. toxicologists). The OpenTox toxicological ontology projects may be accessed via the Open

Conclusion to the special issue: Observed and projected changes in weather and climate extremes

Directory of Open Access Journals (Sweden)

John E. Hay

2016-03-01

The papers in this Special Issue have shown the nature of the scientific and related challenges, the progress made to date, and the challenges, opportunities and constraints yet to be addressed. They have contributed to increased understanding of where, how and why such events manifest themselves, now and into the future. Such insights increase the capacity to manage the risks associated with these events, and thereby reduce the consequences that society might otherwise have suffered.

Neuroscience and Brain Science Special Issue begins in the Malaysian Journal of Medical Sciences

Science.gov (United States)

ABDULLAH, Jafri Malin

2014-01-01

The Malaysian Journal of Medical Sciences and the Orient Neuron Nexus have amalgated to publish a yearly special issue based on neuro- and brain sciences. This will hopefully improve the quality of peer-reviewed manuscripts in the field of fundamental, applied, and clinical neuroscience and brain science from Asian countries. One focus of the Universiti Sains Malaysia is to strengthen neuroscience and brain science, especially in the field of neuroinformatics. PMID:25941457

Overview of Forensic Toxicology, Yesterday, Today and in the Future.

Science.gov (United States)

Chung, Heesun; Choe, Sanggil

2017-01-01

The scope of forensic toxicology has been tremendously expanded over the past 50 years. From two general sections forensic toxicology can be further classified into 8-9 sections. The most outstanding improvement in forensic toxicology is the changes brought by instrumental development. The field of forensic toxicology was revolutionized by the development of immunoassay and benchtop GC-MS in the 1980's and LC-MS-MS in 2000's. Detection of trace amounts of analytes has allowed the use of new specimens such as hair and oral fluids, along with blood and urine. Over a longer period of time, continuous efforts have been made to efficiently extract and separate drug and poison from biological fluids. International endeavors to develop high quality standards and guidelines for drugs and poisons in biological specimens and to promote them in order to increase reliability of laboratories are also part of the recent advancement of forensic toxicology. Interpretation of postmortem toxicology encompasses various factors including postmortem redistribution and stability. Considering the recent trend, the interpretation of toxicological results should account for autopsy findings, crime scene information, and related medical history. The fields of forensic toxicology will continuously develop to improve analysis of target analytes from various specimens, quality assurance program, and results interpretation. In addition, the development of analytical techniques will also contribute further advancement of forensic toxicology. The societies of forensic toxicologists, such as TIAFT, will play an important role for the advancement of forensic toxicology by collaborating and sharing ideas between toxicologists from both developed and developing countries. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

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2017-10-05

Oct 5, 2017 ... culture of Mamak frequenting restaurants in Malaysia, several issue has risen in relation to the .... employment of one group quasi experimental design was noted to be lacked in internal ... Food safety and quality division: ... self-reported practices of food service staff regarding food hygiene in Edirne, Turkey ...

Research Article Special Issue

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pc

2018-05-01

May 1, 2018 ... The issues of information placement are considered on the website of the educational ... At present, a considerable attention is paid to the automation of educational ... schedule from any device quickly, since the system is the WEB service, which allows ... the system adaptation for its use on mobile devices.

Toxicology and Epidemiology: Improving the Science with a Framework for Combining Toxicological and Epidemiological Evidence to Establish Causal Inference

Science.gov (United States)

Adami, Hans-Olov; Berry, Sir Colin L.; Breckenridge, Charles B.; Smith, Lewis L.; Swenberg, James A.; Trichopoulos, Dimitrios; Weiss, Noel S.; Pastoor, Timothy P.

2011-01-01

Historically, toxicology has played a significant role in verifying conclusions drawn on the basis of epidemiological findings. Agents that were suggested to have a role in human diseases have been tested in animals to firmly establish a causative link. Bacterial pathogens are perhaps the oldest examples, and tobacco smoke and lung cancer and asbestos and mesothelioma provide two more recent examples. With the advent of toxicity testing guidelines and protocols, toxicology took on a role that was intended to anticipate or predict potential adverse effects in humans, and epidemiology, in many cases, served a role in verifying or negating these toxicological predictions. The coupled role of epidemiology and toxicology in discerning human health effects by environmental agents is obvious, but there is currently no systematic and transparent way to bring the data and analysis of the two disciplines together in a way that provides a unified view on an adverse causal relationship between an agent and a disease. In working to advance the interaction between the fields of toxicology and epidemiology, we propose here a five-step “Epid-Tox” process that would focus on: (1) collection of all relevant studies, (2) assessment of their quality, (3) evaluation of the weight of evidence, (4) assignment of a scalable conclusion, and (5) placement on a causal relationship grid. The causal relationship grid provides a clear view of how epidemiological and toxicological data intersect, permits straightforward conclusions with regard to a causal relationship between agent and effect, and can show how additional data can influence conclusions of causality. PMID:21561883

EDITORIAL: Fluctuations and noise in photonics and quantum optics: a special issue in memory of Hermann Haus

Science.gov (United States)

Abbott, Derek; Shapiro, Jeffrey H.; Yamamoto, Yoshihisa

2004-08-01

This Special Issue of Journal of Optics B: Quantum and Semiclassical Optics brings together the contributions of various researchers working on theoretical and experimental aspects of fluctuational phenomena in photonics and quantum optics. The topics discussed in this issue extend from fundamental physics to applications of noise and fluctuational methods from quantum to classical systems, and include: bullet Quantum measurement bullet Quantum squeezing bullet Solitons and fibres bullet Gravitational wave inferometers bullet Fluorescence phenomena bullet Cavity QED bullet Photon statistics bullet Noise in lasers and laser systems bullet Quantum computing and information bullet Quantum lithography bullet Teleportation. This Special Issue is published in connection with the SPIE International Symposium on Fluctuations and Noise, held in Santa Fe, New Mexico, on 1-4 June 2003. The symposium contained six parallel conferences, and the papers in this Special Issue are connected to the conference entitled `Fluctuations and Noise in Photonics and Quantum Optics'. This was the first in a series of symposia organized with the support of the SPIE that have greatly contributed to progress in this area. The co-founders of the symposium series were Laszlo B Kish (Texas A&M University) and Derek Abbott (The University of Adelaide). The Chairs of the `Fluctuations and Noise in Photonics and Quantum Optics' conference were Derek Abbott, Jeffrey H Shapiro and Yoshihisa Yamamoto. The practical aspects of the organization were ably handled by Kristi Kelso and Marilyn Gorsuch of the SPIE, USA. Sadly, less than two weeks before the conference, Hermann A Haus passed away. Hermann Haus was a founding father of the field of noise in optics and quantum optics. He submitted three papers to the conference and was very excited to attend; as can be seen in the collection of papers, he was certainly present in spirit. In honour of his creativity and pioneering work in this field, we have

Research Article Special Issue

African Journals Online (AJOL)

2016-05-15

May 15, 2016 ... twice in Iran (Department of Housing and Urban Development,2008,4). Thus, in recent years, ..... For example study of 1200 schoolchildren from four education regions in Tehran Showed that after ... In this case It is expected that be ... In a communication network issue Hierarchy, access and. Sidewalks are ...

Research Article Special Issue

African Journals Online (AJOL)

pc

2017-08-08

Aug 8, 2017 ... presented in the form of a matrix in which processing of vectors is conducted by a conveyor way. ... The modularity of structure of the product systemand standardization of basic operations allow to create ... Thus, the actual issue of modern CT is the organization and hardware support of parallel production.

Advancing Risk Assessment through the Application of Systems Toxicology

Science.gov (United States)

Sauer, John Michael; Kleensang, André; Peitsch, Manuel C.; Hayes, A. Wallace

2016-01-01

Risk assessment is the process of quantifying the probability of a harmful effect to individuals or populations from human activities. Mechanistic approaches to risk assessment have been generally referred to as systems toxicology. Systems toxicology makes use of advanced analytical and computational tools to integrate classical toxicology and quantitative analysis of large networks of molecular and functional changes occurring across multiple levels of biological organization. Three presentations including two case studies involving both in vitro and in vivo approaches described the current state of systems toxicology and the potential for its future application in chemical risk assessment. PMID:26977253

Theory and Theorizing in Nursing Science: Commentary from the Nursing Research Special Issue Editorial Team.

Science.gov (United States)

Jairath, Nalini N; Peden-McAlpine, Cynthia J; Sullivan, Mary C; Vessey, Judith A; Henly, Susan J

Articles from three landmark symposia on theory for nursing-published in Nursing Research in 1968-1969-served as a key underpinning for the development of nursing as an academic discipline. The current special issue on Theory and Theorizing in Nursing Science celebrates the 50th anniversary of publication of these seminal works in nursing theory. The purpose of this commentary is to consider the future of nursing theory development in light of articles published in the anniversary issue. The Editorial Team for the special issue identified core questions about continued nursing theory development, as related to the nursing metaparadigm, practice theory, big data, and doctoral education. Using a dialogue format, the editors discussed these core questions. The classic nursing metaparadigm (health, person, environment, nursing) was viewed as a continuing unifying element for the discipline but is in need of revision in today's scientific and practice climates. Practice theory and precision healthcare jointly arise from an emphasis on individualization. Big data and the methods of e-science are challenging the assumptions on which nursing theory development was originally based. Doctoral education for nursing scholarship requires changes to ensure that tomorrow's scholars are prepared to steward the discipline by advancing (not reifying) past approaches to nursing theory. Ongoing reexamination of theory is needed to clarify the domain of nursing, guide nursing science and practice, and direct and communicate the unique and essential contributions of nursing science to the broader health research effort and of nursing to healthcare.