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Sample records for total sin lugol

  1. The effect of preoperative Lugol's iodine on intraoperative bleeding in patients with hyperthyroidism

    Directory of Open Access Journals (Sweden)

    Yeliz Yilmaz

    2016-08-01

    Conclusion: Preoperative Lugol solution treatment was found to be a significant independent determinant of intraoperative blood loss. Moreover, preoperative Lugol solution treatment decreased the rate of blood flow, and intraoperative blood loss during thyroidectomy.

  2. Colposcopic characteristics and Lugol׳s staining differentiate anal high-grade and low-grade squamous intraepithelial lesions during high resolution anoscopy

    Directory of Open Access Journals (Sweden)

    Naomi Jay

    2015-12-01

    Full Text Available Background: Anal squamous intraepithelial lesions (SIL and cancers are increased in immunocompromised populations. Based upon anatomic and histologic similarities, the cervix is used as the model for anal screening. During cervical colposcopy, acetic acid (AA and Lugol׳s staining (LS result in characteristic changes that help distinguish low-grade (LSIL from high-grade (HSIL. Lesion characteristics were evaluated for their ability to distinguish anal (aLSIL from anal (aHSIL during high-resolution anoscopy after application of AA and LS. Methods: AA-stained lesions were described using standard cervical colposcopic criteria. LS was then applied and lesions were characterized as Lugol׳s-negative (L−, Lugol׳s-partial (L+/−, or Lugol׳s positive (L+ and then biopsied. Biopsies were characterized as benign, squamous atypia, LSIL or HSIL. Results: 835 anal lesions were analyzed. Sensitivity and positive predictive value (PPV for aHSIL were highest for characteristics associated with cervical (cHSIL. L− was independently associated with aHSIL (OR=4.7, 95% CI=3.4–6.7. In multiple logistic regression analysis, significant predictors of aHSIL were flat contour (OR=2.24, 95% CI=1.3–3.8, mosaic pattern (OR=2.0, 95% CI=1.4–2.9, vascular punctation (OR=1.5, 95% CI=1.1–2.1 and L− (OR=2.3, 95% CI=1.5–3.4. L− staining improved the PPV of aHSIL almost twofold in lesions that otherwise had a colposcopic impression of LSIL. Conclusions: Evaluating acetowhite lesions for contour, surface, vascularity, and LS may maximize the likelihood of identifying aHSIL. Keywords: Anal, HSIL, High resolution anoscopy, Lugol׳s staining

  3. High-definition endoscopy with iScan and Lugol's solution for the detection of inflammation in patients with nonerosive reflux disease: histologic evaluation in comparison with a control group.

    Science.gov (United States)

    Rey, J W; Deris, N; Marquardt, J U; Thomaidis, T; Moehler, M; Kittner, J M; Nguyen-Tat, M; Dümcke, S; Tresch, A; Biesterfeld, S; Goetz, M; Mudter, J; Neurath, M F; Galle, P R; Kiesslich, R; Hoffman, A

    2016-01-01

    Nonerosive reflux disease (NERD) is commonly diagnosed in patients with symptoms of reflux. The aim of the present study was to determine whether high-definition endoscopy (HD) plus equipped with the iScan function or chromoendoscopy with Lugol's solution might permit the differentiation of NERD patients from those without reflux symptoms, proven by targeted biopsies of endoscopic lesions. A total of 100 patients without regular intake of proton pump inhibitors and with a normal conventional upper endoscopy were prospectively divided into NERD patients and controls. A second upper endoscopy was performed using HD+ with additional iScan function and then Lugol's solution was applied. Biopsy specimens were taken from the gastroesophageal junction in all patients. A total of 65 patients with reflux symptoms and 27 controls were included. HD(+) endoscopy with iScan revealed subtle mucosal breaks in 52 patients; the subsequent biopsies confirmed esophagitis in all cases. After Lugol's solution, 58 patients showed mucosal breaks. Sensitivity for the iScan procedure was 82.5%, whereas that for Lugol's solution was 92.06%. Excellent positive predictive values of 100% and 98.3%, respectively, were noted. The present study suggests that the majority of patients with NERD and typical symptoms of reflux disease can be identified by iScan or Lugol's chromoendoscopy as minimal erosive reflux disease (ERD) patients. © 2014 International Society for Diseases of the Esophagus.

  4. The effect of preoperative Lugol's iodine on intraoperative bleeding in patients with hyperthyroidism.

    Science.gov (United States)

    Yilmaz, Yeliz; Kamer, Kemal Erdinc; Ureyen, Orhan; Sari, Erdem; Acar, Turan; Karahalli, Onder

    2016-08-01

    To investigate the effect of preoperative Lugol's iodine on intraoperative bleeding in patients with hyperthyroidism. This controlled, randomized, prospective cohort was carried out on 40 patients who admitted for surgery due to hyperthyroidism. Cases were randomly assigned to receive either preoperative treatment with Lugol solution (Group 1) or no preoperative treatment with Lugol solution (Group 2). Group 3 (n = 10) consisted of healthy adults with no known history and signs of hyperthyroidism. Blood flow through the thyroid arteries of patients was measured by color flow Doppler ultrasonography. Free T3, free T4, TSH, thyroid volume and the resistance index of the four main thyroid arteries were measured in all patients. There was not a significant difference between gender, preoperative serum thyroid hormone levels, or thyroid gland volumes between groups 1 and 2. The mean blood flow of the patients in Group 1 was significantly lower than values in Group 2. When age, gender, thyroid hormone, TSH, thyroid volume, blood flow, and Lugol solution treatment were included as independent variables, Lugol solution treatment (OR, 7.40; 95% CI, 1.02-58.46; p = 0.001) was found to be the only significant independent determinant of intraoperative blood loss. Lugol solution treatment resulted in a 7.40-fold decrease in the rate of intraoperative blood loss. Preoperative Lugol solution treatment was found to be a significant independent determinant of intraoperative blood loss. Moreover, preoperative Lugol solution treatment decreased the rate of blood flow, and intraoperative blood loss during thyroidectomy.

  5. Sin Nombre

    DEFF Research Database (Denmark)

    Cristoffanini, Pablo Rolando

    2012-01-01

    steder, de aldrig har stiftet bekendtskab med. Og når man besøger stederne i virkeligheden, vil filmenes typer og stereotyper påvirke mødet og kontakten. I denne artikel vil jeg vise, hvordan en film, Sin nombre (spansk: Uden navn), behandler to af den globaliserede verdens grundlæggende spørgsmål: a...... kun vedkommende, fordi den tager vigtige samfundsmæssige og eksistentielle spørgsmål op, men også fordi den, som kritikerne har påpeget, rent æstetisk er af høj kvalitet. Farver, lyd og de intense scener støtter en god fortælling....

  6. Effect of acid Lugol solution as preservative on two representative chitineous and gelatinous zooplankton groups

    DEFF Research Database (Denmark)

    Jaspers, Cornelia; Carstensen, Jacob

    2009-01-01

    The estimation of biomass from body lengths to carbon regressions is a common approach in plankton research. Several different chemicals for sample preservation are in use, and conversion factors to account for shrinkage effects exist, but to our knowledge the consequences of using potassium......-iodide and iodine (Lugol solution) as preservative on body sizes of different mesozooplankton groups have not been investigated. We tested the effect of 2% acidified Lugol solution on body sizes over time on two major marine mesozooplankton groups, namely larvaceans and copepods, which are representatives...

  7. Rescue pre-operative treatment with Lugol's solution in uncontrolled Graves' disease.

    Science.gov (United States)

    Calissendorff, Jan; Falhammar, Henrik

    2017-05-01

    Graves' disease is a common cause of hyperthyroidism. Three therapies have been used for decades: pharmacologic therapy, surgery and radioiodine. In case of adverse events, especially agranulocytosis or hepatotoxicity, pre-treatment with Lugol's solution containing iodine/potassium iodide to induce euthyroidism before surgery could be advocated, but this has rarely been reported. All patients hospitalised due to uncontrolled hyperthyroidism at the Karolinska University Hospital 2005-2015 and treated with Lugol's solution were included. All electronic files were carefully reviewed manually, with focus on the cause of treatment and admission, demographic data, and effects of iodine on thyroid hormone levels and pulse frequency. Twenty-seven patients were included. Lugol's solution had been chosen due to agranulocytosis in 9 (33%), hepatotoxicity in 2 (7%), other side effects in 11 (41%) and poor adherence to medication in 5 (19%). Levels of free T4, free T3 and heart rate decreased significantly after 5-9 days of iodine therapy (free T4 53-20 pmol/L, P  = 0.0002; free T3 20-6.5 pmol/L, P  = 0.04; heart rate 87-76 beats/min P  = 0.0007), whereas TSH remained unchanged. Side effects were noted in 4 (15%) (rash n  = 2, rash and vomiting n  = 1, swelling of fingers n  = 1). Thyroidectomy was performed in 26 patients (96%) and one was treated with radioiodine; all treatments were without serious complications. Treatment of uncontrolled hyperthyroidism with Lugol's solution before definitive treatment is safe and it decreases thyroid hormone levels and heart rate. Side effects were limited. Lugol's solution could be recommended pre-operatively in Graves' disease with failed medical treatment, especially if side effects to anti-thyroid drugs have occurred. © 2017 The authors.

  8. Effectiveness and Mechanism of Preoperative Lugol Solution for Reducing Thyroid Blood Flow in Patients with Euthyroid Graves' Disease.

    Science.gov (United States)

    Huang, Shih-Ming; Liao, Wei-Ting; Lin, Chiou-Feng; Sun, H Sunny; Chow, Nan-Haw

    2016-03-01

    To reduce intraoperative and postoperative complications, using Lugol solution to preoperatively prepare patients with Graves' disease has (1) rapidly reduced the severity of thyrotoxicosis and (2) reduced the vascularity of the thyroid gland. The vascularity reduction normally accompanies reducing the severity of thyrotoxicosis. However, the effects and mechanism of Lugol solution for reducing blood flow have not been well investigated in the patients with euthyroid (normally functioning thyroid) Graves' disease. Twenty-five patients with euthyroid Graves' disease being preoperatively treated with Lugol solution for 10 days were measured, at baseline and on the operative day, for (1) superior thyroid artery blood flow; (2) systemic angiogenic factor (VEGF); and (3) systemic inflammatory factor [interleukin (IL)-16]. All three parameters were significantly (p Graves' disease. We recommend routine preoperative Lugol solution treatment for all patients with Graves' disease.

  9. Vigilar sin castigar (Medios).

    OpenAIRE

    Ruiz Agila, Gabriela Alejandra

    2015-01-01

    Los imaginarios de las ciudades fronterizas se levantan sobre el mito de ciudades violentas sin historia. Los protagonistas no son otros que bandidos y extranjeros de paso. Siempre son ‘los foráneos’ los culpables. Y el conveniente juego de ‘vigilar sin castigar’ el contrabando y el tráfico de drogas que se repite cotidiano en vibrantes puntos de control como Rumichaca o Huaquillas.

  10. Efecto del fotoperiodo y la razón camarón:macroalga en la remoción de nitrógeno amoniacal total por Gracilaria vermiculophylla, en cultivo con Litopenaeus vannamei, sin recambio de agua

    Directory of Open Access Journals (Sweden)

    Adolfo Sánchez-Romero

    2013-11-01

    Full Text Available Se evaluó el efecto del fotoperiodo y la relación de biomasa camarón:macroalga en la remoción de nitrógeno amoniacal total (NAT, por la macroalga Gracilaria vermiculophylla, en cultivo con camarón Litopenaeus vannamei, sin recambio de agua. Se evaluaron cuatro fotoperiodos: 12:12, 14:10, 16:08 y 24:00 h de luz:oscuridad y dos relaciones de biomasa camarón:macroalga, 1:4 y 1:8. El diseño experimental fue factorial de 4x2 con cuatro réplicas por tratamiento. Las menores concentraciones de NAT (0,55 ± 0,17 mg L-1, N-NO² (0,145 ± 0,29 mg L-1 y N-NO3 (3,13 ± 0,73 mg L-1 se registraron en la relación 1:8. Las mayores tasas de crecimiento de la macroalga (3,07 ± 1,44% día-1 se obtuvieron con fotoperiodo de 24:00 h y relación de biomasa 1:8. La mayor tasa de incorporación de N en la macroalga (0,31 ± 0,12 mg N L-1 día-1 ocurrió en las mismas condiciones. El crecimiento del camarón fue similar al reportado en sistemas tradicionales de recirculación. La integración de G. vermiculophylla en el sistema sin recambio, fue capaz de mantener los niveles de compuestos nitrogenados tóxicos en niveles favorables para el crecimiento de L. vannamei.

  11. When deviance becomes sin

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    Anton Senekal

    1999-03-01

    Full Text Available In this article a brief exposition is given o f what sin and deviance entail. This perspective is approached in terms of what is called the logovision premise. This premise essentially maintains that human perception of reality is primarily mediated through words and that only God's words allow us to see reality as it truly is. Thus we are enabled to respond appropriately to reality - especially evaluative reality. By then applying God’s words to the issues involved in the study of deviance, more clarity is hopefully achieved. This is done by discussing the respective characteristics of sin and deviance and by briefly exploring the relationship between these two phenomena. Finally some of the implications for the study o f social deviance are discussed.

  12. Pp scattering at SIN

    International Nuclear Information System (INIS)

    Aprile-Giboni, E.; Cantale, G.; Hausammann, R.

    1983-01-01

    Using the PM1 polarized proton beam at SIN and a polarized target, the elastic pp scattering as well as the inelastic channel pp → π + d have been studied between 400 and 600 MeV. For the elastic reaction, a sufficient number of spin dependent parameters has been measured in order to do a direct reconstruction of the scattering matrix between 38 0 /sub cm/ and 90 0 /sub cm/. 10 references, 6 figures

  13. 10 years of SIN

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1984-11-15

    The Schweizerisches Institut fur Nuklearforschung (Swiss Institute for Nuclear Research, or SIN) proudly celebrated its 10th anniversary earlier this year. Welcoming the audience at a reception on 22 June, Swiss Federal Councillor Alphons Egli recalled that only about one human lifetime ago was it demonstrated that the atom, despite its name (from the Greek for indivisible), could in fact be split. Since then, questions arising from this discovery have continued to fascinate research workers all over the world.

  14. 10 years of SIN

    International Nuclear Information System (INIS)

    Anon.

    1984-01-01

    The Schweizerisches Institut fur Nuklearforschung (Swiss Institute for Nuclear Research, or SIN) proudly celebrated its 10th anniversary earlier this year. Welcoming the audience at a reception on 22 June, Swiss Federal Councillor Alphons Egli recalled that only about one human lifetime ago was it demonstrated that the atom, despite its name (from the Greek for indivisible), could in fact be split. Since then, questions arising from this discovery have continued to fascinate research workers all over the world

  15. Un conocer sin cegamientos

    Directory of Open Access Journals (Sweden)

    Carolina Ferrante

    2015-08-01

    Full Text Available En el presente artículo se reseña el libro La construcción de marcas de reconocimiento en sociedades ocularcentristas: el caso de mujeres ciegas del Área Metropolitana de Monterrey de Brenda Araceli Bustos García. Se describe el problema de investigación en el cual se inserta la tesis que nutre el libro y se recorre la trama argumental. Finalmente, se realiza una valoración positiva del modo de construcción del objeto de estudio, el cual promueve un conocer sin cegamientos. 

  16. Antiproliferative/cytotoxic effects of molecular iodine, povidone-iodine and Lugol's solution in different human carcinoma cell lines.

    Science.gov (United States)

    Rösner, Harald; Möller, Wolfgang; Groebner, Sabine; Torremante, Pompilio

    2016-09-01

    Clinical trials have revealed that molecular iodine (I 2 ) has beneficial effects in fibrocystic breast disease and in cyclic mastalgia. Likewise, povidone-iodine (PVP-I), which is widely used in clinical practice as an antiseptic agent following tumour surgery, has been demonstrated to have cytotoxic effects on colon cancer and ascites tumour cells. Our previous study indicated that the growth of breast cancer and seven other human malignant cell lines was variably diminished by I 2 and iodolactones. With the intention of developing an iodine-based anticancer therapy, the present investigations extended these studies by comparing the cytotoxic capacities of I 2 , potassium iodide (KJ), PVP-I and Lugol's solution on various human carcinoma cell lines. Upon staining the cell nuclei with Hoechst 33342, the cell densities were determined microscopically. While KJ alone did not affect cell proliferation, it enhanced the antiproliferative activity of I 2 . In addition, PVP-I significantly inhibited the proliferation of human MCF-7 breast carcinoma, IPC melanoma, and A549 and H1299 lung carcinoma cells in a concentration corresponding to 20 µM I 2 . Likewise, Lugol's solution in concentrations corresponding to 20-80 µM I 2 were observed to reduce the growth of MCF-7 cells. Experiments with fresh human blood samples revealed that the antiproliferative activity of PVP-I and I 2 is preserved in blood plasma to a high degree. These findings suggest that PVP-I, Lugol's solution, and a combination of iodide and I 2 may be potent agents for use in the development of antitumour strategies.

  17. [[Abortion: An Unforgivable Sin?].

    Science.gov (United States)

    Lalli, Chiara

    Abortion has become something to hide, something you can't tell other people, something you have to expiate forever. Besides, abortion is more and more difficult to achieve because of the raising average of consciencious objection (from 70 to 90% of health care providers are conscientious objectors, 2014 data, Ministero della Salute) and illegal abortion is "coming back"from the 70s, when abortion was a crime (Italian law n. 194/1978). Abortion is often blamed as a murder, an unforgivenable sin, even as genocide. Silence against shouting "killers!" to women who are going to have an abortion: this is a common actual scenario. Why is it so difficult to discuss and even to mention abortion?

  18. Development and validation of the Single Item Narcissism Scale (SINS).

    Science.gov (United States)

    Konrath, Sara; Meier, Brian P; Bushman, Brad J

    2014-01-01

    The narcissistic personality is characterized by grandiosity, entitlement, and low empathy. This paper describes the development and validation of the Single Item Narcissism Scale (SINS). Although the use of longer instruments is superior in most circumstances, we recommend the SINS in some circumstances (e.g. under serious time constraints, online studies). In 11 independent studies (total N = 2,250), we demonstrate the SINS' psychometric properties. The SINS is significantly correlated with longer narcissism scales, but uncorrelated with self-esteem. It also has high test-retest reliability. We validate the SINS in a variety of samples (e.g., undergraduates, nationally representative adults), intrapersonal correlates (e.g., positive affect, depression), and interpersonal correlates (e.g., aggression, relationship quality, prosocial behavior). The SINS taps into the more fragile and less desirable components of narcissism. The SINS can be a useful tool for researchers, especially when it is important to measure narcissism with constraints preventing the use of longer measures.

  19. Effects of Lugol staining on stenosis formation induced by radiofrequency ablation of esophageal squamous epithelium: a study in a porcine model

    NARCIS (Netherlands)

    Schölvinck, D. W.; Alvarez Herrero, L.; Visser, M.; Bergman, J. J. G. H. M.; Weusten, B. L. A. M.

    2015-01-01

    Preliminary data show higher stricture rates after radiofrequency ablation (RFA) for early esophageal squamous neoplasia compared with Barrett's esophagus. We studied the effects of Lugol stain (LS) directly prior to RFA on stricture formation in squamous epithelium. Of 16 pigs, the distal half of

  20. Pre-Operative Lugol's Iodine Treatment in the Management of Patients Undergoing Thyroidectomy for Graves' Disease: A Review of the Literature.

    Science.gov (United States)

    Hope, Nicholas; Kelly, Andrew

    2017-02-01

    To undertake a review of the relevant English literature published on the pre-operative use of Lugol's iodine in the management of patients undergoing thyroidectomy for Graves' disease. We reviewed all relevant papers found through Ovid Medline, PubMed, EMBASE and the American Thyroid Association website. Searches were limited to the English language only. The critical appraisal tool CASP was used to help analyse the papers. Following this, the evidence was ranked using the Harbour and Miller classification of hierarchy. Four papers were deemed appropriate for analysis. The evidence contained within the review is considered weak. The literature available in the public domain regarding the use of iodinated solutions in the pre-operative period for those patients about to undergo thyroidectomy for Graves' disease is scant. Having undertaken an extensive literature review, we are of the opinion that the evidence on which the American Thyroid Association's guidance on the use of preoperative Lugol's iodine is based is tenuous. There appears to be little in the way of sound clinical evidence that post-operative outcomes are any different following a course of Lugol's iodine. Given the lack of robust clinical evidence regarding the clinical need for iodine solution in the pre-operative period, it appears clear that a larger, prospective, randomised controlled trial of all relevant outcomes - clinical and scientific - is required to answer whether or not patient preparation with Lugol's iodine is in fact necessary prior to operative intervention for Graves' disease.

  1. Personas sin hogar y discapacidad

    Directory of Open Access Journals (Sweden)

    Sonia Panadero Herrero

    2014-12-01

    Full Text Available Este artículo presenta los principales resultados del primer trabajo de investigación específico sobre personas sin hogar y discapacidad llevado a cabo en España.  Dicho estudio se llevó a cabo en dos fases secuenciales. La Fase 1 perseguía cuantificar la existencia de discapacidad entre el colectivo de personas sin hogar para, en la Fase 2, profundizar en la situación de estas personas. Los resultados de la Fase 1, en la que se recogió información sobre 695 personas, mostraron una importante presencia de discapacidad entre las personas sin hogar.  Un 12 % de las personas sin hogar tenía certificado de discapacidad, aunque el porcentaje de discapacidad podría ser muy superior si se considera la percepción de profesionales y usuarios (al menos el 23 %. Los resultados de la Fase 2, en la que se comparaba la situación y características de las personas sin hogar con (81 participantes y sin ella (48 participantes, apuntaron importantes implicaciones de la existencia de la discapacidad entre las personas sin hogar, como una mayor cronificación de la propia situación, mayores dificultades de acceso al empleo, mayor vulnerabilidad a accidentes y agresiones y otros delitos.

  2. Evaluation of double formalin--Lugol's fixation in assessing number and biomass of ciliates: an example of estimations at mesoscale in NE Atlantic.

    Science.gov (United States)

    Karayanni, Hera; Christaki, Urania; Van Wambeke, France; Dalby, Andrew P

    2004-03-01

    Ciliated protozoa are potential grazers of primary and bacterial production and act as intermediaries between picoplankton and copepods and other large suspension feeders. Accurate determination of ciliate abundance and feeding mode is crucial in oceanic carbon budget estimations. However, the impact of different fixatives on the abundance and cell volume of ciliates has been investigated in only a few studies using either laboratory cultures or natural populations. Lugol's solution and formalin are the most commonly used fixatives for the preservation of ciliates samples. In the present study, the aim was to compare 0.4% Lugol's solution and 2% borated-formalin fixation and evaluate the need of counting duplicate samples each using a different fixative. For this, a large number of samples (n = 110) from the NE Atlantic was analyzed in the frame of POMME program (Multidisciplinary Mesoscale Ocean Program). We established a statistically significant relationship (p Tintinnus spp. did not show any difference between the two treatments. Abundance and biomass of mixotrophic ciliates (chloroplast-bearing cells) were for various reasons underestimated in both treatments. Our results show that unique fixation by formalin may severely underestimate ciliates abundance and biomass although their population may not alter. For this reason, Lugol's solution is best for the estimation of their abundance and biomass. However, for counts of mixotrophs and the evaluation of the ecological role of ciliates in carbon flux, double fixation is essential. Compromises regarding the fixatives have lead to severe underestimations of mixotrophs in studies conducted by now.

  3. Diagnostic accuracy of lugol chromoendoscopy in the oesophagus in patients with head and neck cancer Seguridad diagnóstica de la cromoendoscopia con lugol en el esófago de pacientes con cáncer de cabeza y cuello

    Directory of Open Access Journals (Sweden)

    Rita Carvalho

    2013-02-01

    Full Text Available Background and aim: patients with head and neck squamous cell malignancies have a higher risk of oesophageal squamous cell carcinomas. Lugol chromoendoscopy in oesophagus is a simple technique with a high diagnostic yield in premalignant lesions. The objective was to analyze its diagnostic accuracy in dysplasia and carcinoma of the oesophagus in high-risk patients. Methods: prospective study from April/2008 to January/2012 using lugol chromoendoscopy with biopsies of suspicious lugol voiding areas ≥ 5 mm. Patients with head and neck malignancies were included, except the ones with iodine allergy, oesophageal varices and contra-indications to standard endoscopy. The reference method was histopathology. Results: 89 patients were enrolled (mean age 62.8 ± 13.3 years, 87 % men. Primary tumour was located in oropharynx in 37 (41.6 %, in oral cavity in 29 (32.6 % and in the larynx in 23 (25.8 % cases. 40.4 % patients had previous treatments and 87 % reported alcohol or tobacco addition. All exams performed without anaesthesia or complications. Nine suspicious lugol voiding areas were observed and biopsied. Histopathological analysis revealed high-grade dysplasia in 2 (2.2 % and inflammation or normal findings in the others. The sensitivity and specificity for detecting high-grade dysplasia were 100 % and 92 % (95 % CI: 87-97, respectively. Diagnostic accuracy of the test was 92 % (95 % CI: 86-98. Conclusion: lugol staining of the oesophagus during endoscopy seems to be a feasible, safe and justified procedure in high-risk population as it enhances the detection of premalignant lesions.

  4. The ethics of sin taxes.

    Science.gov (United States)

    Green, Rebecca

    2011-01-01

    ABSTRACT The current global economic crisis is forcing governments to consider a variety of methods to generate funds for infrastructure. In the United States, smoking-related illness and an obesity epidemic are forcing public health institutions to consider a variety of methods to influence health behaviors of entire target groups. In this paper, the author uses a public health nursing model, the Public Health Code of Ethics (Public Health Leadership Society, 2002), the American Nurses' Association (ANA) Code of Ethics (2001), and other relevant ethical theory to weigh and balance the arguments for and against the use of sin taxes. A position advocating the limited use of sin taxes is supported as a reasonable stance for the public health professional. © 2010 Wiley Periodicals, Inc.

  5. Pleiotropic roles of Clostridium difficile sin locus

    Science.gov (United States)

    Ou, Junjun; Dupuy, Bruno

    2018-01-01

    Clostridium difficile is the primary cause of nosocomial diarrhea and pseudomembranous colitis. It produces dormant spores, which serve as an infectious vehicle responsible for transmission of the disease and persistence of the organism in the environment. In Bacillus subtilis, the sin locus coding SinR (113 aa) and SinI (57 aa) is responsible for sporulation inhibition. In B. subtilis, SinR mainly acts as a repressor of its target genes to control sporulation, biofilm formation, and autolysis. SinI is an inhibitor of SinR, so their interaction determines whether SinR can inhibit its target gene expression. The C. difficile genome carries two sinR homologs in the operon that we named sinR and sinR’, coding for SinR (112 aa) and SinR’ (105 aa), respectively. In this study, we constructed and characterized sin locus mutants in two different C. difficile strains R20291 and JIR8094, to decipher the locus’s role in C. difficile physiology. Transcriptome analysis of the sinRR’ mutants revealed their pleiotropic roles in controlling several pathways including sporulation, toxin production, and motility in C. difficile. Through various genetic and biochemical experiments, we have shown that SinR can regulate transcription of key regulators in these pathways, which includes sigD, spo0A, and codY. We have found that SinR’ acts as an antagonist to SinR by blocking its repressor activity. Using a hamster model, we have also demonstrated that the sin locus is needed for successful C. difficile infection. This study reveals the sin locus as a central link that connects the gene regulatory networks of sporulation, toxin production, and motility; three key pathways that are important for C. difficile pathogenesis. PMID:29529083

  6. Development and Validation of the Single Item Narcissism Scale (SINS)

    Science.gov (United States)

    Konrath, Sara; Meier, Brian P.; Bushman, Brad J.

    2014-01-01

    Main Objectives The narcissistic personality is characterized by grandiosity, entitlement, and low empathy. This paper describes the development and validation of the Single Item Narcissism Scale (SINS). Although the use of longer instruments is superior in most circumstances, we recommend the SINS in some circumstances (e.g. under serious time constraints, online studies). Methods In 11 independent studies (total N = 2,250), we demonstrate the SINS' psychometric properties. Results The SINS is significantly correlated with longer narcissism scales, but uncorrelated with self-esteem. It also has high test-retest reliability. We validate the SINS in a variety of samples (e.g., undergraduates, nationally representative adults), intrapersonal correlates (e.g., positive affect, depression), and interpersonal correlates (e.g., aggression, relationship quality, prosocial behavior). The SINS taps into the more fragile and less desirable components of narcissism. Significance The SINS can be a useful tool for researchers, especially when it is important to measure narcissism with constraints preventing the use of longer measures. PMID:25093508

  7. Development and validation of the Single Item Narcissism Scale (SINS.

    Directory of Open Access Journals (Sweden)

    Sara Konrath

    Full Text Available MAIN OBJECTIVES: The narcissistic personality is characterized by grandiosity, entitlement, and low empathy. This paper describes the development and validation of the Single Item Narcissism Scale (SINS. Although the use of longer instruments is superior in most circumstances, we recommend the SINS in some circumstances (e.g. under serious time constraints, online studies. METHODS: In 11 independent studies (total N = 2,250, we demonstrate the SINS' psychometric properties. RESULTS: The SINS is significantly correlated with longer narcissism scales, but uncorrelated with self-esteem. It also has high test-retest reliability. We validate the SINS in a variety of samples (e.g., undergraduates, nationally representative adults, intrapersonal correlates (e.g., positive affect, depression, and interpersonal correlates (e.g., aggression, relationship quality, prosocial behavior. The SINS taps into the more fragile and less desirable components of narcissism. SIGNIFICANCE: The SINS can be a useful tool for researchers, especially when it is important to measure narcissism with constraints preventing the use of longer measures.

  8. Image processing and machine learning techniques to automate diagnosis of Lugol's iodine cervigrams for a low-cost point-of-care digital colposcope

    Science.gov (United States)

    Asiedu, Mercy Nyamewaa; Simhal, Anish; Lam, Christopher T.; Mueller, Jenna; Chaudhary, Usamah; Schmitt, John W.; Sapiro, Guillermo; Ramanujam, Nimmi

    2018-02-01

    The world health organization recommends visual inspection with acetic acid (VIA) and/or Lugol's Iodine (VILI) for cervical cancer screening in low-resource settings. Human interpretation of diagnostic indicators for visual inspection is qualitative, subjective, and has high inter-observer discordance, which could lead both to adverse outcomes for the patient and unnecessary follow-ups. In this work, we a simple method for automatic feature extraction and classification for Lugol's Iodine cervigrams acquired with a low-cost, miniature, digital colposcope. Algorithms to preprocess expert physician-labelled cervigrams and to extract simple but powerful color-based features are introduced. The features are used to train a support vector machine model to classify cervigrams based on expert physician labels. The selected framework achieved a sensitivity, specificity, and accuracy of 89.2%, 66.7% and 80.6% with majority diagnosis of the expert physicians in discriminating cervical intraepithelial neoplasia (CIN +) relative to normal tissues. The proposed classifier also achieved an area under the curve of 84 when trained with majority diagnosis of the expert physicians. The results suggest that utilizing simple color-based features may enable unbiased automation of VILI cervigrams, opening the door to a full system of low-cost data acquisition complemented with automatic interpretation.

  9. Ácido tranexámico endovenoso en el reemplazo total de rodilla sin manguito hemostático. [Intravenous­ tranexamic ­acid­ in­ total ­knee­ arthroplasty­ without­ tourniquet.

    Directory of Open Access Journals (Sweden)

    Fernando M. Bidolegui

    2014-10-01

    Full Text Available In­tro­duc­ción: La artroplastia de rodilla se asocia a grandes pérdidas de sangre perioperatorias y posoperatorias (600-1500 ml, y a porcentajes de transfusión de sangre hasta del 50%. El objetivo es estudiar el efecto del ácido tranexámico en la artroplastia primaria de rodilla sin manguito hemostático, valorando la pérdida sanguínea en el posoperatorio. Materiales­ y­ Métodos: Los pacientes fueron asignados, en forma aleatoria, a dos grupos: Grupo A, con ácido tranexámico, 25 pacientes (71,5 años y Grupo B, sin ácido tranexámico, 25 pacientes (72 años. Se determinó la hemoglobina y el hematocrito antes de la cirugía, y a las 24, 48 y 72 h. Se midió el débito del suctor a las 24 h. Resultados: El hematocrito posoperatorio a las 24, 48 y 72 h fue del 33,4%; 31,5% y 30,8%, respectivamente, en el grupo A, y del 28,5%; 27,9% y 27%, en el grupo B (p <0,001 en los 3 registros. Los valores de hemoglobina fueron 11, 10,3 y 10 g/dl en el grupoA y 9,4; 9,3 y 9 g/dl, en el grupo B, respectivamente (p <0,001; p = 0,004 y p = 0,002. La colección del drenaje a las 24 h en el grupo A fue de 363,4 ml (± 141ml y, en el grupo B, fue de 626 ml (± 260 ml (p <0,001. Se transfundió al 32% de los pacientes del grupo B y a ninguno del grupo A. No se registraron casos de enfermedad tromboembólica. Conclusión: El uso de ácido tranexámico disminuye la pérdida de sangre posoperatoria asociada a la artroplastia de rodilla; esto se refleja en menores porcentajes de transfusión de sangre sin un aumento en el riesgo de complicaciones.

  10. Estudio del álbum sin palabras

    OpenAIRE

    Bosch Andreu, Emma

    2015-01-01

    [spa] Estudio del Álbum Sin Palabras tiene como objetivo principal definir, analizar y categorizar los álbumes sin palabras destinados principalmente al público infantil y juvenil dando a conocer sus características, peculiariades y diversidad tipológica, para facilitar las tareas de análisis y de mediación de investigadores, educadores, bibliotecarios y cualquier persona interesada en los libros con imágenes. En el capítulo titulado «Un nuevo mapa para los Libros Sin Palabras» situamos e...

  11. Unscented Kalman filter for SINS alignment

    Institute of Scientific and Technical Information of China (English)

    Zhou Zhanxin; Gao Yanan; Chen Jiabin

    2007-01-01

    In order to improve the filter accuracy for the nonlinear error model of strapdown inertial navigation system (SINS) alignment, Unscented Kalman Filter (UKF) is presented for simulation with stationary base and moving base of SINS alignment.Simulation results show the superior performance of this approach when compared with classical suboptimal techniques such as extended Kalman filter in cases of large initial misalignment.The UKF has good performance in case of small initial misalignment.

  12. Operability of glioblastomas: "sins of action" versus "sins of non-action".

    Science.gov (United States)

    Ferroli, Paolo; Schiariti, Marco; Finocchiaro, Gaetano; Salmaggi, Andrea; Castiglione, Melina; Acerbi, Francesco; Tringali, Giovanni; Farinotti, Mariangela; Broggi, Morgan; Roberto, Cordella; Maccagnano, Elio; Broggi, Giovanni

    2013-12-01

    Despite prognosis of glioblastomas is still poor, mounting evidence suggests that more extensive surgical resections are associated with longer life expectancy. However, the surgical indications, at present, are far from uniform and the concept of operability is extremely surgeon-dependant. The results of glioblastoma resection in 104 patients operated on between March 2005 and April 2011 were reviewed with the aim to shed some light on the limits between 'sins of action' (operating upon complex tumors causing a permanent severe deficit) and 'sins of non-action' (considering inoperable tumors that can be resected with good results). Fifty-five patients (54.4 %) (Group 1) presented with a 'disputable' surgical indication because of one or more of the following clinico-radiological aspects: involvement of motor and language areas (39.4 %), deep location (7.7 %), corpus callosum infiltration (13.4 %), or major vessels encasement (8.6 %). Forty-six (42.5 %) patients (Group 2) presented with an 'indisputable' surgical indication (readily accessible tumors in non-eloquent areas). Overall mortality was 2.9 %. The mean overall survival was 19.8 months and not significantly different in the two Groups (20.4 Group 2 and 19.5 months for Group 1; p = 0.7). Patients with GTR and <72 years had a longer survival (p = 0.004 and 0.03, respectively). Seventy patients (69.3 %) showed an uneventful post-operative course, without statistical significance difference between Group 1 and 2. The gross total removal of glioblastoma with many complexities (Group 1) was found to be feasible with acceptable mortality, morbidity and long-term survival rates.

  13. Sin Stocks in Self Managed Superannuation Funds

    Directory of Open Access Journals (Sweden)

    Peter J. Phillips

    2011-06-01

    Full Text Available Ethical or responsible investing has attracted much attention over the last decade. Financial planners can nowadvise clients on a broad range of ethical investment products and some financial planning firms have this astheir sole activity. Interestingly, the alter ego of ethical investing, sin or vice investing, has attracted far lessattention. Recent research shows that ‘sinful’ investments can generate very strong returns and shouldcertainly not be avoided by investors without a full evaluation of the consequences of excluding theseinvestments from the portfolio. This paper extends these findings into the field of self managedsuperannuation funds operating within an Australian context. The prevalence of sinful investments within asample of SMSFs and the returns that may be generated by a portfolio consisting of sinful Australian equitiesis examined. Analysis reveals that the SMSF investors within the sample do not include very many sin stocksin their portfolios. However, it does not appear as though SMSF trustees are missing an important investmentopportunity because the analysis reveals that an equally-weighted portfolio of all vice or sin shares is unlikelyto generate superior returns.

  14. Determination of naturally occurring radionuclides in El-Sin Water

    International Nuclear Information System (INIS)

    Al-Masri, M.S.; Al-Rayyes, A.H.

    2000-01-01

    Naturally occurring radionuclides levels have been determined in El-Sin water for the period of 1995 and 1996. water samples were collected from four sites, which are the main drinking water sources of the area. Radon concentration was found to vary between 0.88 Bq/1 in Lattakia main water supply site and 8.4 Bq/1 in El-Sin springs.The highest values found for other radionuclides were 51.6 mBq/1, 18.6 mB/1 and 24.8 mBq/1 for sup 2 sup 2 sup 6 Ra, sup 2 sup 1 sup 0 Po and total uranium (sup 2 sup 3 sup 4 U and sup 2 sup 3 sup 8 U) respectively. These levels are much lower than the maximum permissible levels in drinking water set by international organization.(author)

  15. Original antigenic sin responses to influenza viruses.

    Science.gov (United States)

    Kim, Jin Hyang; Skountzou, Ioanna; Compans, Richard; Jacob, Joshy

    2009-09-01

    Most immune responses follow Burnet's rule in that Ag recruits specific lymphocytes from a large repertoire and induces them to proliferate and differentiate into effector cells. However, the phenomenon of "original antigenic sin" stands out as a paradox to Burnet's rule of B cell engagement. Humans, upon infection with a novel influenza strain, produce Abs against older viral strains at the expense of responses to novel, protective antigenic determinants. This exacerbates the severity of the current infection. This blind spot of the immune system and the redirection of responses to the "original Ag" rather than to novel epitopes were described fifty years ago. Recent reports have questioned the existence of this phenomenon. Hence, we revisited this issue to determine the extent to which original antigenic sin is induced by variant influenza viruses. Using two related strains of influenza A virus, we show that original antigenic sin leads to a significant decrease in development of protective immunity and recall responses to the second virus. In addition, we show that sequential infection of mice with two live influenza virus strains leads to almost exclusive Ab responses to the first viral strain, suggesting that original antigenic sin could be a potential strategy by which variant influenza viruses subvert the immune system.

  16. Original Sin and T. E. Hulme's Aesthetics

    Science.gov (United States)

    Kishler, Thomas C.

    1976-01-01

    T. E. Hulme, a vigorous opponent of romanticism in art, poetry, and philosophy, insisted that the underlying flaw of the romantic view was its rejection of the dogma of Original Sin and the fall of man. His views are explored for the significant bearing they have on the development of aesthetic insight and indirectly on value and outlook.…

  17. Original antigenic sin: A comprehensive review.

    Science.gov (United States)

    Vatti, Anup; Monsalve, Diana M; Pacheco, Yovana; Chang, Christopher; Anaya, Juan-Manuel; Gershwin, M Eric

    2017-09-01

    The concept of "original antigenic sin" was first proposed by Thomas Francis, Jr. in 1960. This phenomenon has the potential to rewrite what we understand about how the immune system responds to infections and its mechanistic implications on how vaccines should be designed. Antigenic sin has been demonstrated to occur in several infectious diseases in both animals and humans, including human influenza infection and dengue fever. The basis of "original antigenic sin" requires immunological memory, and our immune system ability to autocorrect. In the context of viral infections, it is expected that if we are exposed to a native strain of a pathogen, we should be able to mount a secondary immune response on subsequent exposure to the same pathogen. "Original antigenic sin" will not contradict this well-established immunological process, as long as the subsequent infectious antigen is identical to the original one. But "original antigenic sin" implies that when the epitope varies slightly, then the immune system relies on memory of the earlier infection, rather than mount another primary or secondary response to the new epitope which would allow faster and stronger responses. The result is that the immunological response may be inadequate against the new strain, because the immune system does not adapt and instead relies on its memory to mount a response. In the case of vaccines, if we only immunize to a single strain or epitope, and if that strain/epitope changes over time, then the immune system is unable to mount an accurate secondary response. In addition, depending of the first viral exposure the secondary immune response can result in an antibody-dependent enhancement of the disease or at the opposite, it could induce anergy. Both of them triggering loss of pathogen control and inducing aberrant clinical consequences. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. CRYOTHERAPY FOLLOWING VISUAL INSPECTION WITH ACETIC ACID AND LUGOL'S IODINE (VIA/VILI) IN KHWISERO, WESTERN KENYA: LESSON FROM THE FIELD AFFECTING POLICY AND PRACTICE.

    Science.gov (United States)

    Ngichabe, S K; Muthaura, P N; Murungi, C; Muyoka, J; Omenge, E; Muchiri, L

    2013-10-01

    Cervical cancer can be prevented and mortality/morbidity reduced by early detection and referral. Developing countries are likely to benefit from more cost effective methods of screening and treatment. Visual inspection with acetic acid and Lugol's iodine (VIA/VILI) offers a see and treat solution thus an affordable and efficient way to identify pre-malignant lesions. Immediate treatment with cryotherapy can be offered if pre-malignant lesions are found on visual inspection. Cryotherapyis a simple procedure that is curative for dysplasia; it is likely to benefit cervical dysplasia cases picked early in resource poor settings, however there are several factors that hinder patients' access to this noble technique. Determine hindrances to cryotherapy for patients following positive results of VIA/VILI after referral. Cross sectional Study Khwisero, Western Kenya. Women attending a medical camp, willing to get screened for cervical cancer. One hundred and nine patients were screened; seventy three (66.97%) were negative for VIA/VILI, twenty one (19.26%) were positive and referred for cryotherapy. Reasons for lack of follow up were financial constraints, lack of medical personnel at referral centres and poor access to the referral facilities.19.26% of women identified with positive lesions required intervention. No patient received cryotherapy following referral. There is urgent need for availability of cryotherapy machines and training of personnel who can perform cryotherapy at the primary care level. Regional studies on knowledge attitudes and practices about VIA/VILI and cryotherapy are required to provide reasons for the poor uptake of this procedure.

  19. Advertising and the Seven Sins of Memory

    DEFF Research Database (Denmark)

    Percy, Larry

    2004-01-01

    A positive intention may be formed as a result of exposure to an advertisement, but if a memory malfunction interferes with that intention, the advertising will be ineffective.This paper considers the implications for advertisers of Daniel Schacter’s ‘seven sins of memory’: transcience, absent......-mindedness, blocking, misattribution, suggestibility, bias and persistence. Each of the ‘sins’ is explained in detail and advice provided for advertisers on how to avoid these pitfalls....

  20. Monarcas y súbditos ''sin cualidades''

    OpenAIRE

    Raminelli, Ronald

    2011-01-01

    En Brasil, no siempre los primeros colonizadores disponían del honor necesario para recibir los beneficios concedidos por el Rey. En general, cuando no se trataba de mestizos y mulatos, las elites locales se originaban en las antiguas cepas judías. Mismo siendo súbditos sin cualidad, los reyes les concedieron perdón y algunos privilegios. Los títulos de caballero concedidos a los mestizos e hijos ilegítimos permiten de alguna forma vislumbrar la debilidad de las fuerzas que unían a las partes...

  1. The Swiss Institute for Nuclear Research SIN

    CERN Document Server

    Pritzker, Andreas

    2014-01-01

    This book tells the story of the Swiss Institute for Nuclear Research (SIN). The institute was founded in 1968 and became part of the Paul Scherrer Institute (PSI) in 1988. Its founding occurred at a time when physics was generally considered the key discipline for technological and social development. This step was unusual for a small country like Switzerland and showed courage and foresight. Equally unusual were the accomplishments of SIN, compared with similar institutes in the rest of the world, as well as its influence on Swiss, and partially also on international politics of science. That this story is now available in a widely understandable form is due to the efforts of some physicists, who took the initiative as long as contemporary witnesses could still be questioned. As is usually the case, official documents always show just an excerpt of what really happened. An intimate portrayal of people who contributed to success requires personal memories. This text relies on both sources. In addition, the e...

  2. Measurement of the cp violation parameter sin 2 beta

    International Nuclear Information System (INIS)

    K.F. Kelley

    1999-01-01

    This thesis presents a measurement of the time-dependent asymmetry in the rate of (anti B) d 0 versus B d 0 decays to J/ψK s 0 . In the context of the Standard Model this is interpreted as a measurement of the CP violation parameter sin(2β). A total of 198±17 B d 0 /(anti B) d 0 decays were observed in p(anti p) collisions at √s=1.8 TeV by the CDF detector at the Fermilab Tevatron. The initial B flavor (whether B 0 or (anti B) 0 ) is determined by a same-side flavor tagging technique. The analysis results in sin(2β)=1.8±1.1(stat.)±0.3(syst.). This analysis demonstrates the feasibility of studying CP violation in the B 0 -(anti B) 0 system at a hadron collider. By applying the methods used in this analysis, future, higher-statistics experiments should be able to tightly constrain the parameters of the Standard Model

  3. En Caracas: una radio sin antena

    Directory of Open Access Journals (Sweden)

    José Tomás Angola

    2015-01-01

    Full Text Available Cuenta la experiencia única de la radio comunitaria Parque Central de Caracas (1994 donde al decir de su director y concesionario de la estación se necesitó compromiso, esfuerzo, romanticismo y comunidad. Creada como un sistema de seguridad y publicidad surgió por iniciativa de la Asociación de vecinos de la Etapa 1 donde viven más de 12 mil personas Funciona sin estar dentro de los patrones transmisor-Antena-Receptor, no se encuentra regulada por ninguna ley, son a decir de Marañón el medio de comunicación más libre del país donde la comunidad se expresa por sobre la economía, la técnica y la ley.

  4. Un mundo sin límites

    Directory of Open Access Journals (Sweden)

    Córdoba, Joaquín Mª

    2005-04-01

    Full Text Available A comienzos del siglo XVI, las nuevas ediciones del Atlas de Ptolomeo publicadas en Roma o Venecia solían incluir un mapamundi modificado sin cesara a medida que descubridores y navegantes alcanzaban nuevos y antes desconocidos horizontes. La temprana circunnavegación de Magallanes y Elcano (1519-1522 confirmaba con su esferidad, que el mundo no tenía límites. Durante aquel siglo magnífico, la literatura española de viajes al Oriente Próximo islámico tenía que ser menos señalada. La casi perenne guerra contra el Imperio Otomano, señor de una buena parte de las costas mediterráneas, y sobre todo la empresa de América y los viajes de exploración y conquista que aquella demandaba, …

  5. Bicarbonate Plays a Critical Role in the Generation of Cytotoxicity during SIN-1 Decomposition in Culture Medium

    Directory of Open Access Journals (Sweden)

    Kyo Shirai

    2012-01-01

    Full Text Available 3-Morpholinosydnonimine (SIN-1 is used as a donor of peroxynitrite (ONOO− in various studies. We demonstrated, however, that, the cell-culture medium remains cytotoxic to PC12 cells even after almost complete SIN-1 decomposition, suggesting that reaction product(s in the medium, rather than ONOO−, exert cytotoxic effects. Here, we clarified that significant cytotoxicity persists after SIN-1 decomposes in bicarbonate, a component of the culture medium, but not in NaOH. Cytotoxic SIN-1-decomposed bicarbonate, which lacks both oxidizing and nitrosating activities, degrades to innocuous state over time. The extent of SIN-1 cytotoxicity, irrespective of its fresh or decomposed state, appears to depend on the total number of initial SIN-1 molecules per cell, rather than its concentration, and involves oxidative/nitrosative stress-related cell damage. These results suggest that, despite its low abundance, the bicarbonate-dependent cytotoxic substance that accumulates in the medium during SIN-1 breakdown is the cytotoxic entity of SIN-1.

  6. JUAN SIN MIEDO VA A LA ESCUELA

    Directory of Open Access Journals (Sweden)

    Silvia Méndez-Anchía

    2009-01-01

    Full Text Available Tomando como base la lectura del cuento "Juan Sin Miedo" realizada por tres sujetos adolescentes, pretendo responder a la pregunta sobre los principales temores que enfrenta la población costarricense adolescente en la actualidad. Las respuestas giran en torno a tres núcleos significativos: el miedo a la exclusión económica y social, materializada en el trato discriminatorio hacia quienes no se adecuan a los criterios impuestos por la sociedad de consumo; el miedo a la escuela, en tanto excluye a quienes no se ajustan a la norma esperada de desempeño académico; y el miedo al otro, en particular a la calle y la escuela como espacios de violencia. Concluyo señalando que, detrás de dichos temores, es posible leer un anhelo de pertenencia; de aprecio sincero y gratuito, en que no medie el rendimiento académico de la persona; así como un anhelo de seguridad en el entorno cercano.

  7. The seven sins of memory: implications for self.

    Science.gov (United States)

    Schacter, Daniel L; Chiao, Joan Y; Mitchell, Jason P

    2003-10-01

    We examine the relation between memory and self by considering errors of memory. We draw on the idea that memory's imperfections can be classified into seven basic categories or "sins." Three of the sins concern different types of forgetting (transience, absent-mindedness, and blocking), three concern different types of distortion (misattribution, suggestibility, and bias), and one concerns intrusive memories (persistence). We focus in particular on two of the distortion-related sins, misattribution and bias. By describing cognitive, neuropsychological, and neuroimaging studies that illuminate these memory sins, we consider how they might bear on the relation between memory and self.

  8. Novel liquid chromatography–mass spectrometry method for sensitive determination of the mustard allergen Sin a 1 in food

    OpenAIRE

    Alvarez-Llamas, Gloria; Maes, Xavier; Muñoz-García, Esther; Villalba, Mayte; Rodríguez, Rosalía; Pérez-Gordo, Marina; Vivanco, Fernando; Pérez-Gordo, Carlos; Cuesta-Herranz, Javier

    2015-01-01

    Mustard is a condiment added to a variety of foodstuffs and a frequent cause of food allergy. A new strategy for the detection of mustard allergen in food products is presented. The methodology is based on liquid chromatography analysis coupled to mass spectrometry. Mustard allergen Sin a 1 was purified from yellow mustard seeds. Sin a 1 was detected with a total of five peptides showing a linear response (lowest LOD was 5 ng). Sin a 1 was detected in mustard sauces and salty biscuit (19 ± 3 ...

  9. Judeo - Igbo traditional religious conception of sin: socio – religious ...

    African Journals Online (AJOL)

    Theword sin ismore of a religious termthan ordinary. It is basically an action of defiance. That is, an action through which one deviates from the correct way or through which one misses the mark. This paper looked at how the Jews of theOld andNewTestament periods understood the concept of sin in their society.

  10. Sin, Punishment And Forgiveness In Ancient Greek Religion: A ...

    African Journals Online (AJOL)

    This paper looks in particular at the special sin of hubris in ancient Greek religious thought. It examines what constitutes hubris and some cases in which hubris has been committed and punished. It demonstrates with examples that hubris is an unforgivable sin in ancient Greek religion and examines the reasons for this ...

  11. THE HEIDELBERG CATECHISM ON HUMAN SIN AND MISERY

    African Journals Online (AJOL)

    Produced by SUN MeDIA Bloemfontein .... invites us to look at sin in terms of our fundamental alienation from God. And if sin-talk is therefore ..... the social structures created by the human race, but that we nevertheless have a measure of free ...

  12. Misattribution, false recognition and the sins of memory.

    OpenAIRE

    Schacter, D L; Dodson, C S

    2001-01-01

    Memory is sometimes a troublemaker. Schacter has classified memory's transgressions into seven fundamental 'sins': transience, absent-mindedness, blocking, misattribution, suggestibility, bias and persistence. This paper focuses on one memory sin, misattribution, that is implicated in false or illusory recognition of episodes that never occurred. We present data from cognitive, neuropsychological and neuroimaging studies that illuminate aspects of misattribution and false recognition. We firs...

  13. SIN3A mutations are rare in men with azoospermia.

    Science.gov (United States)

    Miyamoto, T; Koh, E; Tsujimura, A; Miyagawa, Y; Minase, G; Ueda, Y; Namiki, M; Sengoku, K

    2015-11-01

    A loss of function of the murine Sin3A gene resulted in male infertility with Sertoli cell-only syndrome (SCOS) phenotype in mice. Here, we investigated the relevance of this gene to human male infertility with azoospermia caused by SCOS. Mutation analysis of SIN3A in the coding region was performed on 80 Japanese patients. However, no variants could be detected. This study suggests a lack of association of SIN3A gene sequence variants with azoospermia caused by SCOS in humans. © 2014 Blackwell Verlag GmbH.

  14. Omission and other sins: Tracking the quality of online machine ...

    African Journals Online (AJOL)

    Omission and other sins: Tracking the quality of online machine translation output over four years. ... Journal Home > Vol 46 (2016) > ... We believe users should be made aware of the risks they unknowingly take when using online MT.

  15. SINS/CNS Nonlinear Integrated Navigation Algorithm for Hypersonic Vehicle

    Directory of Open Access Journals (Sweden)

    Yong-jun Yu

    2015-01-01

    Full Text Available Celestial Navigation System (CNS has characteristics of accurate orientation and strong autonomy and has been widely used in Hypersonic Vehicle. Since the CNS location and orientation mainly depend upon the inertial reference that contains errors caused by gyro drifts and other error factors, traditional Strap-down Inertial Navigation System (SINS/CNS positioning algorithm setting the position error between SINS and CNS as measurement is not effective. The model of altitude azimuth, platform error angles, and horizontal position is designed, and the SINS/CNS tightly integrated algorithm is designed, in which CNS altitude azimuth is set as measurement information. GPF (Gaussian particle filter is introduced to solve the problem of nonlinear filtering. The results of simulation show that the precision of SINS/CNS algorithm which reaches 130 m using three stars is improved effectively.

  16. THE POSTERIOR DISTRIBUTION OF sin(i) VALUES FOR EXOPLANETS WITH MT sin(i) DETERMINED FROM RADIAL VELOCITY DATA

    International Nuclear Information System (INIS)

    Ho, Shirley; Turner, Edwin L.

    2011-01-01

    Radial velocity (RV) observations of an exoplanet system giving a value of M T sin(i) condition (i.e., give information about) not only the planet's true mass M T but also the value of sin(i) for that system (where i is the orbital inclination angle). Thus, the value of sin(i) for a system with any particular observed value of M T sin(i) cannot be assumed to be drawn randomly from a distribution corresponding to an isotropic i distribution, i.e., the presumptive prior distribution. Rather, the posterior distribution from which it is drawn depends on the intrinsic distribution of M T for the exoplanet population being studied. We give a simple Bayesian derivation of this relationship and apply it to several 'toy models' for the intrinsic distribution of M T , on which we have significant information from available RV data in some mass ranges but little or none in others. The results show that the effect can be an important one. For example, even for simple power-law distributions of M T , the median value of sin(i) in an observed RV sample can vary between 0.860 and 0.023 (as compared to the 0.866 value for an isotropic i distribution) for indices of the power law in the range between -2 and +1, respectively. Over the same range of indices, the 95% confidence interval on M T varies from 1.0001-2.405 (α = -2) to 1.13-94.34 (α = +2) times larger than M T sin(i) due to sin(i) uncertainty alone. More complex, but still simple and plausible, distributions of M T yield more complicated and somewhat unintuitive posterior sin(i) distributions. In particular, if the M T distribution contains any characteristic mass scale M c , the posterior sin(i) distribution will depend on the ratio of M T sin(i) to M c , often in a non-trivial way. Our qualitative conclusion is that RV studies of exoplanets, both individual objects and statistical samples, should regard the sin(i) factor as more than a 'numerical constant of order unity' with simple and well-understood statistical

  17. The seven sins in academic behavior in the natural sciences.

    Science.gov (United States)

    van Gunsteren, Wilfred F

    2013-01-02

    "Seven deadly sins" in modern academic research and publishing can be condensed into a list ranging from poorly described experimental or computational setups to falsification of data. This Essay describes these sins and their ramifications, and serves as a code of best practice for researchers in their quest for scientific truth. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Stress engineering in GaN structures grown on Si(111) substrates by SiN masking layer application

    Energy Technology Data Exchange (ETDEWEB)

    Szymański, Tomasz, E-mail: tomasz.szymanski@pwr.edu.pl; Wośko, Mateusz; Paszkiewicz, Bogdan; Paszkiewicz, Regina [The Faculty of Microsystem Electronics and Photonics, Wrocaw University of Technology, Janiszewskiego 11/17, 50-372 Wroclaw (Poland); Drzik, Milan [International Laser Center, Ilkovicova 3, 841-04 Bratislava 4 (Slovakia)

    2015-07-15

    GaN layers without and with an in-situ SiN mask were grown by using metal organic vapor phase epitaxy for three different approaches used in GaN on silicon(111) growth, and the physical and optical properties of the GaN layers were studied. For each approach applied, GaN layers of 1.4 μm total thickness were grown, using silan SiH{sub 4} as Si source in order to grow Si{sub x}N{sub x} masking layer. The optical micrographs, scanning electron microscope images, and atomic force microscope images of the grown samples revealed cracks for samples without SiN mask, and micropits, which were characteristic for the samples grown with SiN mask. In situ reflectance signal traces were studied showing a decrease of layer coalescence time and higher degree of 3D growth mode for samples with SiN masking layer. Stress measurements were conducted by two methods—by recording micro-Raman spectra and ex-situ curvature radius measurement—additionally PLs spectra were obtained revealing blueshift of PL peak positions with increasing stress. The authors have shown that a SiN mask significantly improves physical and optical properties of GaN multilayer systems reducing stress in comparison to samples grown applying the same approaches but without SiN masking layer.

  19. Understanding original antigenic sin in influenza with a dynamical system.

    Science.gov (United States)

    Pan, Keyao

    2011-01-01

    Original antigenic sin is the phenomenon in which prior exposure to an antigen leads to a subsequent suboptimal immune response to a related antigen. Immune memory normally allows for an improved and rapid response to antigens previously seen and is the mechanism by which vaccination works. I here develop a dynamical system model of the mechanism of original antigenic sin in influenza, clarifying and explaining the detailed spin-glass treatment of original antigenic sin. The dynamical system describes the viral load, the quantities of healthy and infected epithelial cells, the concentrations of naïve and memory antibodies, and the affinities of naïve and memory antibodies. I give explicit correspondences between the microscopic variables of the spin-glass model and those of the present dynamical system model. The dynamical system model reproduces the phenomenon of original antigenic sin and describes how a competition between different types of B cells compromises the overall effect of immune response. I illustrate the competition between the naïve and the memory antibodies as a function of the antigenic distance between the initial and subsequent antigens. The suboptimal immune response caused by original antigenic sin is observed when the host is exposed to an antigen which has intermediate antigenic distance to a second antigen previously recognized by the host's immune system.

  20. The human dark side: evolutionary psychology and original sin.

    Science.gov (United States)

    Lee, Joseph; Theol, M

    2014-04-01

    Human nature has a dark side, something important to religions. Evolutionary psychology has been used to illuminate the human shadow side, although as a discipline it has attracted criticism. This article seeks to examine the evolutionary psychology's understanding of human nature and to propose an unexpected dialog with an enduring account of human evil known as original sin. Two cases are briefly considered: murder and rape. To further the exchange, numerous theoretical and methodological criticisms and replies of evolutionary psychology are explored jointly with original sin. Evolutionary psychology can partner with original sin since they share some theoretical likenesses and together they offer insights into the nature of what it means to be human.

  1. Sin, suffering, and the need for the theological virtues.

    Science.gov (United States)

    Jones, David Albert

    2006-08-01

    This article examines the account of the relationship between sin and suffering provided by J. L. A. Garcia in "Sin and Suffering in a Catholic Understanding of Medical Ethics," in this issue. Garcia draws on the (Roman) Catholic tradition and particularly on the thought of Thomas Aquinas, who remains an important resource for Catholic theology. Nevertheless, his interpretation of Thomas is open to criticism, both in terms of omissions and in terms of positive claims. Garcia includes those elements of Thomas that are purely philosophical, such as natural law and acquired virtue, but neglects the theological and infused virtues, the gifts and fruits of the Holy Spirit, and the beatitudes. These omissions distort his account of the Christian life so that he underplays both the radical problem posed by sin (and suffering), and the radical character of the ultimate solution: redemption in Christ through the grace of the Holy Spirit.

  2. The original risk: overtheologizing ethics and undertheologizing sin.

    Science.gov (United States)

    Müller, Denis

    2007-01-01

    The project of articulating a theological ethics on the basis of liturgical anthropology is bound to fail if the necessary consequence is that one has to quit the forum of critical modern rationality. The risk of Engelhardt's approach is to limit rationality to a narrow vision of reason. Sin is not to be understood as the negation of human holiness, but as the negation of divine holiness. The only way to renew theological ethics is to understand sin as the anthropological and ethical expression of the biblical message of the justification by faith only. Sin is therefore a secondary category, which can only by interpreted in light of the positive manifestation of liberation, justification, and grace. The central issue of Christian ethics is not ritual purity or morality, but experience, confession and recognition of our own injustice in our dealing with God and men.

  3. Prediction of the electron redundant SinNn fullerenes

    Science.gov (United States)

    Yang, Huihui; Song, Yan; Zhang, Yan; Chen, Hongshan

    2018-05-01

    The stabilities and electronic structures of SimAln-mNn and SinNn (n = 16, 20, m = 12 and n = 24, m = 16) fullerene-like cages have been investigated using density functional method B3LYP and the second-order perturbation theory MP2. The results show that the SimAln-mNn and SinNn fullerenes are more stable than the AlN counterparts. Comparing with the corresponding AlnNn cages, one silicon atom in each Si2N2 square protrudes and the excess electrons reside as lone pair electrons at the outside of the protrudent Si atoms. Analyses on the electronic structures suggest that the Sisbnd N bonds are covalent bonding with strong polarity. The ELF (electron localization function) shows large electron pair probability between Si and N atoms. The orbital interactions between Si and N are stronger than that between Al and N atoms; the overlap integral is 0.40 per Sisbnd N bond in SinNn and 0.34 per Alsbnd N bond in AlnNn. The AIM (atoms in molecule) charges on the Al atoms in AlnNn and SimAln-mNn are 2.37 and 2.40. The charges on the in-plane and protrudent Si atoms are about 2.88 and 1.50 respectively. Considering the large local dipole moments around the protrudent Si atoms, the electrostatic interactions are also favorable to the SiN cages.

  4. The deadly sins of high technology: Superphenix, Eurotunnel, Ariane 5.

    International Nuclear Information System (INIS)

    Bell, R.; Jeanmougin, Ch.

    1998-01-01

    Based on a detailed analysis of civil or military high technology projects (Superphenix reactor, English Channel tunnel, Ariane 5 launcher, etc..), mainly of European origin, this book reveals seven systematic sins in the realization of these projects: an abolishment of controls, a premature construction, a manumission of suppliers, a no-share of risks attitude, political manipulations, fraudulence and secrecy. (J.S.)

  5. Resisting the therapeutic reduction: on the significance of sin.

    Science.gov (United States)

    Delkeskamp-Hayes, Corinna

    2007-01-01

    Sin-talk, though politically incorrect, is indispensable. Placing human life under the "hermeneutic of sin" means acknowledging that one ought to aim flawlessly at God, and that one can fail in this endeavor. None of this can be appreciated within the contemporary post-Christian, mindset, which has attempted to reduce religion to morality and culture. In such a secular context, the guilt-feelings connected with the recognition of sin are considered to be harmful; the eternal benefit of a repentance is disregarded. Nevertheless, spirituality appears to have therapeutic benefits. Therefore attempts are made to re-locate within healthcare a religion shorn of its transcendent claims, so as then to harvest the benefits of a spirituality "saved from sin". This reduction of religiosity to its therapeutic function is nourished by a post-modern constructivist construal of religion. This article critically examines the dis-ingenuity marring such recasting, as well as the incoherence of related attempts to reduce transcendence to solidarity, and to re-shape the significance of religious rituals.

  6. Ja kun sinä helluni (2/4, 3/4 F)

    OpenAIRE

    2011-01-01

    Laulun sanat: Ja kun sinä helluni, meillen tuut, älä ketäkään tervehtele, aja vain hevoses tallin eteen äläkä ujostele! Ja kun sinä, helluni, meillen tuut, niin tule sinä illalla hiljaa! Tule sinä naapurin pellon poikki ja älä sinä polje viljaa!

  7. Parametric excitation of a SiN membrane via piezoelectricity

    Directory of Open Access Journals (Sweden)

    Shuhui Wu

    2018-01-01

    Full Text Available We develop a stoichiometric silicon nitride (SiN membrane-based electromechanical system, in which the spring constant of the mechanical resonator can be dynamically controlled via piezoelectric actuation. The degenerate parametric amplifier is studied in this configuration. We observe the splitting of mechanical mode in the response spectra of a phase-sensitive parametric amplifier. In addition, we demonstrate that the quality factor Q of the membrane oscillator can be significantly enhanced by more than two orders of magnitude due to the coherent amplification, reaching an effective Q factor of ∼3 × 108 at room temperature. The nonlinear effect on the parametric amplification is also investigated, as well as the thermomechanical noise squeezing. This system offers the possibility to integrate electrical, optical and mechanical degrees of freedom without compromising the exceptional material properties of SiN membranes, and can be a useful platform for studying cavity optoelectromechanics.

  8. Notes on "bioethics and sin" by Jean-Francois Collange.

    Science.gov (United States)

    Cozby, Dimitri

    2005-08-01

    Placing the notion of sin in the context of a meontic account of evil, and emphasizing the effect of sin on the sinner himself, this commentary exposes the insufficiency of restricting oneself to human efforts at atonement, and of thus underemphasizing the role of Christ. Collange's claim that the teaching of "predestination" is rooted in Paul and that the doctrine of merits and indulgences is rooted in Augustine is criticized, and Luther's "forensic" understanding is linked with Augustine, rather than with Paul. Collange's reduction of the concern for holiness to respect and trust is contrasted with holiness's essential context of loving unification with God. The commentary closes by exposing the unsatisfactory scantiness of Collange's treatment of cloning, health-care economy, and of the evils of life.

  9. Parametric excitation of a SiN membrane via piezoelectricity

    Science.gov (United States)

    Wu, Shuhui; Sheng, Jiteng; Zhang, Xiaotian; Wu, Yuelong; Wu, Haibin

    2018-01-01

    We develop a stoichiometric silicon nitride (SiN) membrane-based electromechanical system, in which the spring constant of the mechanical resonator can be dynamically controlled via piezoelectric actuation. The degenerate parametric amplifier is studied in this configuration. We observe the splitting of mechanical mode in the response spectra of a phase-sensitive parametric amplifier. In addition, we demonstrate that the quality factor Q of the membrane oscillator can be significantly enhanced by more than two orders of magnitude due to the coherent amplification, reaching an effective Q factor of ˜3 × 108 at room temperature. The nonlinear effect on the parametric amplification is also investigated, as well as the thermomechanical noise squeezing. This system offers the possibility to integrate electrical, optical and mechanical degrees of freedom without compromising the exceptional material properties of SiN membranes, and can be a useful platform for studying cavity optoelectromechanics.

  10. ¿Cirugía coronaria sin bomba para todos?

    Directory of Open Access Journals (Sweden)

    José María Melero Tejedor

    2006-10-01

    Full Text Available En la pasada década importantes desarrollos técnicos han hecho posible que la cirugía coronaria sin circulación extracorpórea se convierta en un procedimiento rutinario y reproducible. Se presenta la evolución de esta técnica en nuestro hospital durante estos 10 años, el protocolo quirúrgico utilizado, los resultados obtenidos y las motivaciones para extender su uso a todos los pacientes. A pesar de las controversias suscitadas, se espera que la cirugía coronaria sin circulación extracorpórea continúe expandiéndose y los futuros cirujanos cardíacos deben estar preparados para ello.

  11. Adaptive Federal Kalman Filtering for SINS/GPS Integrated System

    Institute of Scientific and Technical Information of China (English)

    杨勇; 缪玲娟

    2003-01-01

    A new adaptive federal Kalman filter for a strapdown integrated navigation system/global positioning system (SINS/GPS) is given. The developed federal Kalman filter is based on the trace operation of parameters estimation's error covariance matrix and the spectral radius of update measurement noise variance-covariance matrix for the proper choice of the filter weight and hence the filter gain factors. Theoretical analysis and results from simulation in which the SINS/GPS was compared to conventional Kalman filter are presented. Results show that the algorithm of this adaptive federal Kalman filter is simpler than that of the conventional one. Furthermore, it outperforms the conventional Kalman filter when the system is undertaken measurement malfunctions because of its possession of adaptive ability. This filter can be used in the vehicle integrated navigation system.

  12. The black Arab as a substitution for sin and guilt

    Directory of Open Access Journals (Sweden)

    Petrović Radmilo

    2009-01-01

    Full Text Available The figure of the Black Arab as a form of guilt and sin is a well-established memorial pattern throughout the Mediterranean world, having already existed for more than 3000 years. This text is focused on two different types of interpretation of the Black Stone and its semantic relation with the symbolized figure of Black Arab in the oral traditions of Mediterranean peoples - Jewish religion and Islamic eschatology. The transformation of the signification of the Black Stone was transferred to the Islamic religion in the act of pilgrimage. The Jewish practice of transferring sin and guilt is related with the Iranian-Manichean Ahura Mazda-Ahriman, and the ancient Greek goddess Hecate. All manifestations of the Black Arab left a deep trace on Slavic spiritual life through the Slavic gods Chernobog, Triglav and Toyan and consequently on the deeply rooted conception of all Slavic peoples that the Black Arab was a black demon of death and the underworld.

  13. Misattribution, false recognition and the sins of memory.

    Science.gov (United States)

    Schacter, D L; Dodson, C S

    2001-09-29

    Memory is sometimes a troublemaker. Schacter has classified memory's transgressions into seven fundamental 'sins': transience, absent-mindedness, blocking, misattribution, suggestibility, bias and persistence. This paper focuses on one memory sin, misattribution, that is implicated in false or illusory recognition of episodes that never occurred. We present data from cognitive, neuropsychological and neuroimaging studies that illuminate aspects of misattribution and false recognition. We first discuss cognitive research examining possible mechanisms of misattribution associated with false recognition. We also consider ways in which false recognition can be reduced or avoided, focusing in particular on the role of distinctive information. We next turn to neuropsychological research concerning patients with amnesia and Alzheimer's disease that reveals conditions under which such patients are less susceptible to false recognition than are healthy controls, thus providing clues about the brain mechanisms that drive false recognition. We then consider neuroimaging studies concerned with the neural correlates of true and false recognition, examining when the two forms of recognition can and cannot be distinguished on the basis of brain activity. Finally, we argue that even though misattribution and other memory sins are annoying and even dangerous, they can also be viewed as by-products of adaptive features of memory.

  14. Is n sin θ conserved along the light path?

    Science.gov (United States)

    Noorbala, Mahdiyar; Sepehrinia, Reza

    2016-03-01

    Snell’s law states that the quantity n{sin}θ is unchanged in refraction of light passing from one medium to another. We inquire whether this is true in the general case where the speed of light varies continuously within a medium. It turns out to be an instructive exercise in application of Snell’s law and Fermat’s principle. It also provides good pedagogical problems in calculus of variations to deal with the subtleties of a variable domain of integration and inclusion of constraints. The final result of these exercises is that, contrary to an initial expectation, the answer to the question in the title is negative.

  15. Inventario de Sobrecarga en Cuidadores Familiares sin Formación Especializada de Enfermos de Alzheimer

    Directory of Open Access Journals (Sweden)

    María del Carmen Pérez-Fuentes

    2017-01-01

    Full Text Available Antecedentes/Objetivo: La demencia tipo Alzheimer es una de las causas más frecuentes de dependencia en población mayor, a lo que se une, la considerable demanda de cuidados. Además, cuando el cuidador es un familiar o una persona sin formación especializada, el cuidado tiene un impacto sobre su salud. Para conocer las necesidades de estos cuidadores y evaluar el nivel de sobrecarga o malestar del cuidador, se realiza la propuesta del Inventario de Sobrecarga en Cuidadores Familiares sin Formación Especializada de Enfermos de Alzheimer (IPSO-CA24. Método: En base a las respuestas de 255 cuidadores, se analizaron las propiedades psicométricas del cuestionario, mediante análisis de fiabilidad, análisis factoriales exploratorios y confirmatorios. Resultados: Los análisis factoriales informan de una estructura de seis factores relacionados (Reacción ante el diagnóstico, Salud física, Sintomatología psicológica (cuidador, Sintomatología conductual (enfermo, Conocimientos de la enfermedad y Nivel de dependencia, con una fiabilidad entre 0,75 y 0,93, que explican el 66,52% de la varianza total. También se obtiene apoyo para su validez convergente. Conclusiones: El IPSO-CA24 viene a dar respuesta a la necesidad de un instrumento que permita una valoración multidimensional de la sobrecarga del cuidador familiar sin formación especializada. © 2017 Asociación Española de Psicología Conductual. Published by Elsevier España, S.L.U. This is an open access article under the CC BY−NC−ND license (http://creativecommons. org/licenses/by−nc−nd/4.0/.

  16. The Doctrine of Original Antigenic Sin: Separating Good From Evil.

    Science.gov (United States)

    Monto, Arnold S; Malosh, Ryan E; Petrie, Joshua G; Martin, Emily T

    2017-06-15

    The term "original antigenic sin" was coined approximately 60 years ago to describe the imprinting by the initial first influenza A virus infection on the antibody response to subsequent vaccination. These studies did not suggest a reduction in the response to current antigens but instead suggested anamnestic recall of antibody to earlier influenza virus strains. Then, approximately 40 years ago, it was observed that sequential influenza vaccination might lead to reduced vaccine effectiveness (VE). This conclusion was largely dismissed after an experimental study involving sequential administration of then-standard influenza vaccines. Recent observations have provided convincing evidence that reduced VE after sequential influenza vaccination is a real phenomenon. We propose that such reduction in VE be termed "negative antigenic interaction," given that there is no age cohort effect. In contrast, the potentially positive protective effect of early influenza virus infection later in life continues to be observed. It is essential that we understand better the immunologic factors underlying both original antigenic sin and negative antigenic interaction, to support development of improved influenza vaccines and vaccination strategies. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.

  17. At finde sin stemme på dansk

    DEFF Research Database (Denmark)

    Frederiksen, Karen-Margrete

    2013-01-01

    At finde sin stemme på dansk/ Finding your voice in Danish It is a general experience of foreigners in Denmark that Danes and other speakers of Danish tend to switch into English when the foreigners try to use and practice their Danish. In this article, I focus on foreign knowledge workers working...... at Danish universities and their experiences with finding their voice in Danish in an environment where English is frequently used. At CIP, Centre for Internationalisation and Parallel Language Use, we are developing a format for Danish courses aimed at foreign knowledge workers. Central to the development...... of the course is how to make it possible for the participants to practice their Danish and have a voice in Danish outside the classroom. In this article, I discuss different reasons why people switch into English when speaking with learners of Danish and the implications it may have, both for the learners...

  18. Loss of the SIN3 transcriptional corepressor results in aberrant mitochondrial function

    Directory of Open Access Journals (Sweden)

    Hüttemann Maik

    2010-07-01

    Full Text Available Abstract Background SIN3 is a transcriptional repressor protein known to regulate many genes, including a number of those that encode mitochondrial components. Results By monitoring RNA levels, we find that loss of SIN3 in Drosophila cultured cells results in up-regulation of not only nuclear encoded mitochondrial genes, but also those encoded by the mitochondrial genome. The up-regulation of gene expression is accompanied by a perturbation in ATP levels in SIN3-deficient cells, suggesting that the changes in mitochondrial gene expression result in altered mitochondrial activity. In support of the hypothesis that SIN3 is necessary for normal mitochondrial function, yeast sin3 null mutants exhibit very poor growth on non-fermentable carbon sources and show lower levels of ATP and reduced respiration rates. Conclusions The findings that both yeast and Drosophila SIN3 affect mitochondrial activity suggest an evolutionarily conserved role for SIN3 in the control of cellular energy production.

  19. Total protein

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/003483.htm Total protein To use the sharing features on this page, please enable JavaScript. The total protein test measures the total amount of two classes ...

  20. Electronic properties of a new structured Sin/O superlattice

    Directory of Open Access Journals (Sweden)

    S. Yu

    2016-11-01

    Full Text Available Silicon is a material which dominants the semiconductor industry and has a well-established processing technology based on it. However, silicon has an indirect-bandgap and is not efficient in light emitting. This limits its applications in optoelectronics. In this paper, we proposed a new structural model for the silicon-based superlattice, i.e., the Sin/O one. The model consists of alternating films of n-layers of Si and a monolayer of oxygen along z-direction, together with a surface cell of Si(001 (2×1 reconstruction in the x-y plane. The importance of employing such a Si(001 (2×1 reconstruction is that all the electrons at interface can be strongly bonded. Our results showed interesting electronic properties, e.g., the band folding and large band gap of bulk Si, when the thickness of the silicon layers was increased (but still thin. Our structure might also offer other interesting properties.

  1. Sin and suffering in a Catholic understanding of medical ethics.

    Science.gov (United States)

    Garcia, J L A

    2006-08-01

    Drawing chiefly on recent sources, in Part One I sketch an untraditional way of articulating what I claim to be central elements of traditional Catholic morality, treating it as based in virtues, focused on the recipients ("patients") of our attention and concern, and centered in certain person-to-person role-relationships. I show the limited and derivative places of "natural law," and therefore of sin, within that framework. I also sketch out some possible implications for medical ethics of this approach to moral theory, and briefly contrast these with the influential alternative offered by the "principlism" of Beauchamp and Childress. In Part Two, I turn to a Catholic understanding of the nature and meaning of human suffering, drawing especially on writings and addresses of the late Pope John Paul II. He reminds us that physical and mental suffering can provide an opportunity to share in Christ's salvific sacrifice, better to see the nature of our earthly vocation, and to reflect on the dependence that inheres in human existence. At various places, and especially in my conclusion, I suggest a few ways in which this can inform bioethical reflection on morally appropriate responses to those afflicted by physical or mental pain, disability, mental impairment, disease, illness, and poor health prospects. My general point is that mercy must be informed by appreciation of the person's dignity and status. Throughout, my approach is philosophical rather than theological.

  2. Early Christian spiritualties of sin and forgiveness according to 1 John

    Directory of Open Access Journals (Sweden)

    Dirk G. van der Merwe

    2014-05-01

    Full Text Available The article attempts to investigate the possible lived experiences created by this text. The text revolves around the experience of fellowship with God (1:6, 7 who is characterised as ‘light’. For the author of 1 John, sin disrupts this fellowship. He creates an awareness and a ‘spirituality of sin and guilt’ in the lives of his readers through the use of the experiential metaphor of darkness in a dialectic combination with light and the two false negations ‘do not have sin’ (sin as a noun and ‘do not sin’ (sin as a verb. This fellowship is re-established through living in the light: the confession, forgiveness and expiation of sin. The author creates a spirituality of confession, forgiveness and expiation of sin through descriptive cultic (blood of Jesus and expiation, forensic (paraclete, atypical (cleans, expiation, paraclete and all-inclusive (all [twice], whole, anyone language. Thus, in his rhetoric, the author uses metaphor, dialectic, sacrificial, forensic, atypical and all-inclusive language to facilitate a variety of ‘lived experiences’ within his readers. Firstly, he wants them to feel guilty about their sins and consequently, after they have confessed their sins, to strengthen their faith. Secondly, he wants to encourage them to believe that they can experience the forgiveness of their sins and, by doing so, know that they have eternal life (5:13 and can experience fellowship with God and, mutually, with one another.

  3. Theoretical study of isoelectronic SinM clusters (M=Sc-,Ti,V+; n=14-18)

    DEFF Research Database (Denmark)

    Torres, M. B.; Fernandez Sanchez, Eva; Balbás, L. C.

    2007-01-01

    We study, from first-principles quantum mechanical calculations, the structural and electronic properties of several low-lying energy equilibrium structures of isoelectronic SinM clusters (M=Sc-,Ti,V+) for n=14-18. The main result is that those clusters with n=16 are more stable than its neighbors...... of the spherical potential model). The structures of the two lowest energy isomers of Si16M are nearly degenerate, and consist of the Frank-Kasper polyhedron and a distortion of that polyhedron. The first structure is the ground state for M=V+, and the second is the ground state for Ti and Sc-. For the lowest...... energy isomers of clusters SinM with n=14-18, we analyze the changes with size n, and impurity M of several quantities: binding energy, second difference of total energy, HOMO-LUMO gap, adiabatic electron affinity, addition energy of a Si atom, and addition energy of an M impurity to a pure Si-n cluster...

  4. Crustáceos decápodos de la cuenca del Río Sinú, Córdoba, Colombia

    Directory of Open Access Journals (Sweden)

    Jorge Alexander Quirós Rodríguez

    2016-09-01

    Full Text Available Para evaluar la composición, abundancia y distribución de los crustáceos decápodos en la cuenca del río Sinú, departamento de Córdoba (Colombia, se estudiaron ocho localidades: cuatro en el río Sinú y cuatro en el complejo cenagoso del bajo Sinú. Para ello, se realizaron seis muestreos entre abril de 2005 y mayo de 2006. En total se registraron 458 crustáceos decápodos distribuidos en tres familias, seis géneros y ocho especies. La familia mejor representada fue Trichodactylidae con cuatro géneros y cuatro especies, seguida de Palaemonidae con un género y tres especies, mientras que de la familia Atyidae solo registró una especie. Especies como Macrobrachium carcinus y M. acanthurus, presentaron el rango más amplio de distribución, siendo características tanto para el rio Sinú como para el CCBS. Entre las especies identificadas, Atya crassa en el río Sinú y Trichodactylus quinquedentatus en el CCBS son nuevos registros para el departamento de Córdoba.

  5. Development of flameless combustion; Desarrollo de la combustion sin flama

    Energy Technology Data Exchange (ETDEWEB)

    Flores Sauceda, M. Leonardo; Cervantes de Gortari, Jaime Gonzalo [Universidad Nacional Autonoma de Mexico, Mexico, D.F. (Mexico)]. E-mail: 8344afc@prodigy.net.mx; jgonzalo@servidor.unam.mx

    2010-11-15

    The paper intends contribute to global warming mitigation joint effort that develops technologies to capture the CO{sub 2} produced by fossil fuels combustion and to reduce emission of other greenhouse gases like the NO{sub x}. After reviewing existing combustion bibliography is pointed out that (a) touches only partial aspects of the collective system composed by Combustion-Heat transfer process-Environment, whose interactions are our primary interest and (b) most specialists think there is not yet a clearly winning technology for CO{sub 2} capture and storage. In this paper the study of combustion is focused as integrated in the aforementioned collective system where application of flameless combustion, using oxidant preheated in heat regenerators and fluent gas recirculation into combustion chamber plus appropriated heat and mass balances, simultaneously results in energy saving and environmental impact reduction. [Spanish] El trabajo pretende contribuir al esfuerzo conjunto de mitigacion del calentamiento global que aporta tecnologias para capturar el CO{sub 2} producido por la combustion de combustibles fosiles y para disminuir la emision de otros gases invernadero como NOx. De revision bibliografica sobre combustion se concluye que (a) trata aspectos parciales del sistema compuesto por combustion-proceso de trasferencia de calor-ambiente, cuyas interacciones son nuestro principal interes (b) la mayoria de especialistas considera no hay todavia una tecnologia claramente superior a las demas para captura y almacenaje de CO{sub 2}. Se estudia la combustion como parte integrante del mencionado sistema conjunto, donde la aplicacion de combustion sin flama, empleando oxidante precalentado mediante regeneradores de calor y recirculacion de gases efluentes ademas de los balances de masa y energia adecuados, permite tener simultaneamente ahorros energeticos e impacto ambiental reducido.

  6. Diseño, sin ambigüedades.

    Directory of Open Access Journals (Sweden)

    Rómulo Flórez Polo

    2015-07-01

    Full Text Available Este artículo compila y amplía algunos textos de artículos, ensayos y conferencias de los autores como una reflexión sobre la dimensión disciplinaria del Diseño ante la importancia de desarrollar o precisar sus alcances, limitaciones y características como modo de pensar y facilitar su inserción como factor de desarrollo social y productivo. A partir de un depurado o más preciso uso del vocabulario relacionado, y para reducir los riesgos de distorsión en su interpretación se explícita el sentido de la terminología utilizada y los conceptos propuestos. El trabajo se presenta en dos partes. En la primera, acotada en este artículo (sin pretender definir el Diseño se intenta clarificar su naturaleza como recurso del pensamiento creativo, analizando los principales aspectos que caracterizan o definen su esencia como actividad distintiva de la especie, en su relación social y con el medio. En la segunda, en un artículo consecutivo, se propone un conjunto de descriptores —categorías, variables o factores— que al establecer y precisar las particularidades de lo que es o puede ser el Diseño como disciplina permiten: a.- en lo general, diferenciarla frente a otras disciplinas, profesiones, ejercicios, oficios, ciencias y saberes reconocidos tradicionalmente como tales; y, b.- en lo específico, tomar conciencia sobre su singularidad, y entenderla como un recurso innovador para modificar nuestra relación individual y social con el entorno como seres pensantes, autónomos, responsables de nuestras necesidades y posibilidades y por los efectos que de su satisfacción y ejercicio se derivan.

  7. Original Mycobacterial Sin, a consequence of highly homologous antigens?

    Science.gov (United States)

    Jenkins, A O; Michel, A; Rutten, V

    2017-05-01

    The role of antigens shared between Mycobacteria in in-vivo cross-reactive immune responses in host animals, have been reported to be responsible for reduced BCG vaccination efficacy as well reduced specificity of routine immunological diagnostic tests. This presents with significant disease control challenges in humans and animals. The present review highlights the results of previous studies on the effect of pre-sensitization to environmental mycobacteria on either pathogenic mycobacteria and/or M. bovis BCG, in experimental animals. It also takes an in-depth view into assessing the genetic similarities and relationships between atypical mycobacteria and Mycobacterium tuberculosis complex (MTBC) and how they might explain the immunological imprint of environmental mycobacteria in directing the hosts' immune response upon subsequent exposure to other classes of mycobacteria. The outcome of this review suggests that genetic closeness between particular atypical mycobacteria and MTBC usually indicate a higher level of homology for certain shared protective antigens. This ultimately results in a higher level of cross reactive immune responses as compared with other atypical mycobacteria that are further away genetically. This would explain the different effects of environmental mycobacteria on MTBC that have been reported in the different studies. In other words the direction of the host immune system in response to exposure to MTBC would depend on the type of environmental mycobacteria that was encountered in the initial exposure. We also explain these mycobacterial interactions in the context of the phenomenon of "Original Mycobacterial Sin". The effects of these inevitable mycobacterial interactions on field diagnosis and control by vaccination and how to circumvent them are discussed. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  8. Total algorithms

    NARCIS (Netherlands)

    Tel, G.

    We define the notion of total algorithms for networks of processes. A total algorithm enforces that a "decision" is taken by a subset of the processes, and that participation of all processes is required to reach this decision. Total algorithms are an important building block in the design of

  9. Sobredentadura total superior implantosoportada

    Directory of Open Access Journals (Sweden)

    Luis Orlando Rodríguez García

    2010-06-01

    Full Text Available Se presenta un caso de un paciente desdentado total superior, rehabilitado en la consulta de implantología de la Clínica "Pedro Ortiz" del municipio Habana del Este en Ciudad de La Habana, Cuba, en el año 2009, mediante prótesis sobre implantes osteointegrados, técnica que se ha incorporado a la práctica estomatológica en Cuba como alternativa al tratamiento convencional en los pacientes desdentados totales. Se siguió un protocolo que comprendió una fase quirúrgica, procedimiento con o sin realización de colgajo y carga precoz o inmediata. Se presenta un paciente masculino de 56 años de edad, que acudió a la consulta multidisciplinaria, preocupado, porque se le habían elaborado tres prótesis en los últimos dos años y ninguna reunía los requisitos de retención que él necesitaba para sentirse seguro y cómodo con las mismas. El resultado final fue la satisfacción total del paciente, con el mejoramiento de la calidad estética y funcional.

  10. Calvin’s modification of Augustine’s doctrine of original sin

    Directory of Open Access Journals (Sweden)

    N. Vorster

    2010-07-01

    Full Text Available Augustine was Calvin’s main source of reference in the “Insti- tutes”. However, his treatment of Augustine’s views was not uncritical. This article discusses the way in which Calvin modi- fied Augustine’s doctrine of original sin. The main differences can be attributed to different theological aims. Augustine deve- loped his doctrine of original sin against the teachings of the Manicheans and Pelagians, whereas Calvin shifted the focus to knowledge of God and the self. Calvin understood original sin noetically as religious and moral blindness – whereas Augus- tine viewed sexual concupiscence as the main principle of original sin. Augustine made a considerable effort to explain that sin does not find its origin in God. God foresaw the fall, but did not compel it. Calvin located sin in God’s eternal decree and permission. Augustine, furthermore, understood the transmis- sion of original sin biologically, whereas Calvin ascribed it to God’s eternal permissive will. These differences culminated in a different understanding of the meaning of Jesus’ virgin birth. The article concludes by discussing the relevance of Calvin’s noetic approach to original sin.

  11. Temporal Analysis of Andes Virus and Sin Nombre Virus Infections of Syrian Hamsters

    Science.gov (United States)

    2007-05-01

    Microbiology . All Rights Reserved. Temporal Analysis of Andes Virus and Sin Nombre Virus Infections of Syrian Hamsters Victoria Wahl-Jensen,1 Jennifer...Ye, C., J. Prescott , R. Nofchissey, D. Goade, and B. Hjelle. 2004. Neutralizing antibodies and Sin Nombre virus RNA after recovery from hantavirus

  12. preescolares desnutridos con madres con obesidad y sin obesidad

    Directory of Open Access Journals (Sweden)

    Viridiana Vanessa Conzuelo-González

    2009-01-01

    Full Text Available El primer objetivo fue conocer cuántos menores de cinco años con diferentes grados de desnutrición tienen una madre con sobrepeso/obesidad/ en una comunidad indígena que vive en extrema pobreza y bajo condiciones de migración masculina internacional. El segundo fue comparar tres variables socionutricionales (ingreso familiar, educación de la madre y adecuación nutrimental de la dieta diaria entre estos hogares y los hogares con desnutrición infantil y madres sin obesidad. Se realizó un estudio transversal (2006-2007, en la comunidad mazahua de San Francisco Tepeolulco, Municipio de Temascalcingo; que incluyó a 85 hogares integrados por preescolares con desnutrición inscritos al programa Oportunidades. Se determinó el estado nutrición de los preescolares con indicadores antropométricos y se obtuvo el IMC de las madres de estos infantes. Se aplicó una encuesta socionutricional, incluida el recordatorio de 24 horas, y complementado con la observación participante (cualitativa. Se encontró que 83% de las madres mazahuas presentaron sobrepeso u obesidad. El estado de nutrición de los preescolares con madres con obesidad presentó un porcentaje mayor de desnutrición (76%. En la variable género, se encontró que 54% de los niños con madres con obesidad tenía baja talla. Al relacionar el nivel educativo de la madre, esta variable resultó ser estadísticamente significativa (p=0.015, donde el analfabetismo está más relacionado con la desnutrición infantil que tienen madres de bajo y/o peso normal. La elevada prevalencia de hogares conformados con preescolares con desnutrición y madres con obesidad, es un síntoma más de la pobreza en zonas indígenas en México, con bajo índice de desarrollo humano.

  13. Measurement of sin2θw and ϱ in deep inelastic neutrino-nucleon scattering

    Science.gov (United States)

    Reutens, P. G.; Merritt, F. S.; Macfarlane, D. B.; Messner, R. L.; Novikoff, D. B.; Purohit, M. V.; Blair, R. E.; Sciulli, F. J.; Shaevitz, M. H.; Fisk, H. E.; Fukushima, Y.; Jin, B. N.; Kondo, T.; Rapidis, P. A.; Yovanovitch, D. D.; Bodek, A.; Coleman, R. N.; Marsh, W. L.; Fackler, O. D.; Jenkins, K. A.

    1985-03-01

    We describe a high statistics measurement from deep inelastic neutrino-nucleon scattering of the electroweak parameters ϱ and sin2θw, performed in the Fermilab narrow-band neutrino beam. Our measurement uses a radius-dependent cut in y = EH/Ev which reduces the systematic error in sin2θw, and incorporates electromagnetic and electroweak radiative corrections. In a renormalization scheme where sin2θw ≡ 1-m2W/m2Z, a value of sin2θw = 0.242+/-0.011+/-0.005 is obtained fixing ϱ = 1. If both sin2θw and ϱ are allowed to vary in a fit to our data, we measure ϱ = 0.991 +/- 0.025 +/- 0.009. Present address: IBM Thomas J. Watson Research Center, PO Box 218, Yorktown Heights, NY 10598, USA.

  14. The seven sins of memory. Insights from psychology and cognitive neuroscience.

    Science.gov (United States)

    Schacter, D L

    1999-03-01

    Though often reliable, human memory is also fallible. This article examines how and why memory can get us into trouble. It is suggested that memory's misdeeds can be classified into 7 basic "sins": transience, absentmindedness, blocking, misattribution, suggestibility, bias, and persistence. The first three sins involve different types of forgetting, the next three refer to different types of distortions, and the final sin concerns intrusive recollections that are difficult to forget. Evidence is reviewed concerning each of the 7 sins from relevant sectors of psychology (cognitive, social, and clinical) and from cognitive neuroscience studies that include patients with focal brain damage or make use of recently developed neuroimaging techniques. Although the 7 sins may appear to reflect flaws in system design, it is argued instead that they are by-products of otherwise adaptive features of memory.

  15. Totally James

    Science.gov (United States)

    Owens, Tom

    2006-01-01

    This article presents an interview with James Howe, author of "The Misfits" and "Totally Joe". In this interview, Howe discusses tolerance, diversity and the parallels between his own life and his literature. Howe's four books in addition to "The Misfits" and "Totally Joe" and his list of recommended books with lesbian, gay, bisexual, transgender,…

  16. Dma1-dependent degradation of SIN proteins during meiosis in Schizosaccharomyces pombe.

    Science.gov (United States)

    Krapp, Andrea; Simanis, Viesturs

    2014-07-15

    The Schizosaccharomyces pombe septation initiation network (SIN) is required for cytokinesis during vegetative growth and for spore formation during meiosis. Regulation of the SIN during mitosis has been studied extensively, but less is known about its meiotic regulation. Here, we show that several aspects of SIN regulation differ between mitosis and meiosis. First, the presence of GTP-bound Spg1p is not the main determinant of the timing of Cdc7p and Sid1p association with the spindle pole body (SPB) during meiosis. Second, the localisation dependencies of SIN proteins differ from those in mitotic cells, suggesting a modified functional organisation of the SIN during meiosis. Third, there is stage-specific degradation of SIN components in meiosis; Byr4p is degraded after meiosis I, whereas the degradation of Cdc7p, Cdc11p and Sid4p occurs after the second meiotic division and depends upon the ubiquitin ligase Dma1p. Finally, Dma1p-dependent degradation is not restricted to the SIN, as we show that Dma1p is needed for the degradation of Mcp6p (also known as Hrs1p) during meiosis I. Taken together, these data suggest that stage-specific targeted proteolysis plays an important role in regulating meiotic progression. © 2014. Published by The Company of Biologists Ltd.

  17. The Trauma of Racism: America's Original Sin

    Science.gov (United States)

    Ponds, Kenneth T.

    2013-01-01

    With the election of Barack Obama as President, many believed that this nation was entering into a post-racial America, a color-blind society where racism could begin to be healed if not totally dismissed. However, a recent Associated Press poll has shown that this is not the case (AP, 2012). In fact, racial prejudice has increased slightly since…

  18. La comunicación expresiva en niños con multidiscapacidad sin lenguaje verbal

    Directory of Open Access Journals (Sweden)

    María Alejandra GRAZONA

    2011-04-01

    Full Text Available La investigación estuvo centrada en niños con multidiscapacidad que se comunican a través de canales no visuales y no verbales. A partir de la pregunta central respecto a: ¿Cómo dan a conocer el contenido de sus mensajes los niños con multidiscapacidad que no poseen lenguaje verbal?, implementamos un estudio con dos fases complementarias y de convergencia metodológica. La primera, amparada en el paradigma positivista, en la que realizamos un acercamiento objetivo a la realidad y por medio de la operacionalización de los conceptos teóricos. en la segunda fase, profundizamos a través de la Metodología de estudio de Caso (9 en total y con un anclaje en el paradigma fenomenológico-interpretativo. El objetivo perseguido fue: Conocer las formas comunicativas de niños con multidiscapacidad sin lenguaje verbal, por ello privilegiamos el análisis en profundidad a partir de la utilización de diferentes técnicas que permitieron el acercamiento a los niños en ambientes naturales y triangular la información para proporcionar fiabilidad y validez. Las mencionadas etapas permitieron obtener un conocimiento holístico de las formas comunicativas idiosincráticas utilizadas por los niños con multidiscapacidad, que, a modo de bisagra, constituyen su fenotipo comunicativo.

  19. A Precision Measurement of sin$^{2}\\theta$$_{w}$ from Semileptonic Neutrino Scattering

    CERN Document Server

    Wotschack, Jorg

    1987-01-01

    There is considerable interest in measuring the electroweak mixing parameter sin$^{2}\\Theta$$_{w}$, of the Glashow-Salam-Weinberg theory $^{1}$ as precisely as possible: first, its value may be predicted by models of Grand Unification;$^{2}$ second, precise measurements of sin$^{2}\\Theta$$_{w}$ from different processes would test the validity of electroweak radiative corrections. $^{3,$}$. Different methods have been used to determine sin$^{2}\\Theta$$_{w}$, over a large range of $Q^{2}$ values. FIGURE 1 gives a compilation of sin$^{2}\\Theta$$_{w}$ with remarkable agreement between the results. At present, it is most precisely determined in semileptonic neutrino-nucleon scattering from the ratio of neutral current (NC) to charged current (CC) cross and in proton-antiproton collisions from the W boson mass. $^{10,11}$.

  20. Análisis del tiempo de reacción en personas con y sin discapacidad intelectual en función del deporte practicado

    Directory of Open Access Journals (Sweden)

    Diego Peinado Palomin

    2015-01-01

    Full Text Available El objetivo de este estudio ha sido analizar las dife - rencias en cuanto al tiempo de reacción (TR ante un estímulo visual entre deportistas con discapacidad inte - lectual y sin discapacidad, así como comparar las dife - rencias en función del género y el deporte que se prac - tica. Para ello participaron un total de 38 deportistas (19 con discapacidad intelectual y 19 sin discapacidad divididos en función del deporte que practicaban: at - letismo, natación, deportes colectivos, gimnasia y artes marciales. El instrumento utilizado fue el Dynavision D2, un reacciómetro visual que manda estímulos de forma sucesiva a los deportistas para que respondan de forma rápida. Se demostró que el TR es menor en deportis - tas sin discapacidad en comparación a deportistas con discapacidad (p < 0.05, no apreciándose diferencias significativas en el TR entre sujetos con y sin discapa - cidad que realizaban artes marciales, ni al comparar cada grupo entre los distintos deportes practicados. Los valores medios de tiempo de reacción son mayores en hombres que en mujeres en ambos grupos, aunque no se apreciaron diferencias significativas entre ellos. Los resultados de este estudio ayudarían a planificar mejor el entrenamiento de estos deportistas.

  1. Nuclear effects and the NuTeV sin2 θW measurement

    International Nuclear Information System (INIS)

    McFarland, K.S.; Zeller, G.P.; Adams, T.; Alton, A.; Avvakumov, S.; Barbaro, L. de; Barbaro, P. de; Bernstein, R.H.; Bodek, A.; Bolton, T.; Brau, J.; Buchholz, D.; Budd, H.; Bugel, L.; Conrad, J.; Drucker, R.B.; Fleming, B.T.; Frey, R.; Formaggio, J.A.; Goldman, J.; Goncharov, M.; Harris, D.A.; Johnson, R.A.; Kim, J.H.; Koutsoliotas, S.; Lamm, M.J.; Marsh, W.; Mason, D.; McDonald, J.; McNulty, C.; Naples, D.; Nienaber, P.; Radescu, V.; Romosan, A.; Sakumoto, W.K.; Schellman, H.; Shaevitz, M.H.; Spentzouris, P.; Stern, E.G.; Suwonjandee, N.; Tzanov, M.; Vakili, M.; Vaitaitis, A.; Yang, U.K.; Yu, J.; Zimmerman, E.D.

    2002-01-01

    NuTeV measures sin 2 θ W by comparing neutral and charged current cross-sections on a heavy nuclear target, and finds a value of sin 2 θ W (on-shell) = 0.2277 ± 0.0013(stat) ± 0.0009(syst), approximately 3σ from the predicted value. We discuss the possibility that nuclear effects on parton distribution functions or cross-sections may be responsible for the discrepancy

  2. Interaction between NBS1 and the mTOR/Rictor/SIN1 complex through specific domains.

    Directory of Open Access Journals (Sweden)

    Jian-Qiu Wang

    Full Text Available Nijmegen breakage syndrome (NBS is a chromosomal-instability syndrome. The NBS gene product, NBS1 (p95 or nibrin, is a part of the Mre11-Rad50-NBS1 complex. SIN1 is a component of the mTOR/Rictor/SIN1 complex mediating the activation of Akt. Here we show that NBS1 interacted with mTOR, Rictor, and SIN1. The specific domains of mTOR, Rictor, or SIN1 interacted with the internal domain (a.a. 221-402 of NBS1. Sucrose density gradient showed that NBS1 was located in the same fractions as the mTOR/Rictor/SIN1 complex. Knockdown of NBS1 decreased the levels of phosphorylated Akt and its downstream targets. Ionizing radiation (IR increased the NBS1 levels and activated Akt activity. These results demonstrate that NBS1 interacts with the mTOR/Rictor/SIN1 complex through the a.a. 221-402 domain and contributes to the activation of Akt activity.

  3. A Critical Investigation of the Relationship between Death and Sin in the Works of St. Augustine

    Directory of Open Access Journals (Sweden)

    Ghasem kakaie

    2016-09-01

    Full Text Available Death has been an everlasting human question. It has been regarded as one of the existential and human epistemic concerns both in religions and various philosophical and theological schools. The question of death in the works of Saint Augustine has been largely dismissed by scholars. Scrutinizing his oeuvre indicates that compared to his predecessors and based on his approach to Christianity, specifically to St. Paul’s doctrines, Augustine is more attentive to the relation between death and sin. In his works, he justifies death based on the original sin as well as those everyday sins that committed by human being throughout her life, identifying sin as the cause of death. Accordingly, he prefers moral causes rather than natural causes resulting in death. Augustine contends that there are three types of death, i.e. corporeal death (the separation of soul and body, spiritual death (separation of human being and God due to sin, and the eternal death (in which soul remains in body, bearing the burden of eternal corporeal punishment away from God. He believes that God created a human being in a way according to which she would have benefited from eternal life if she had not sinned. However, now not only corporeal death but also the eternal death of soul are the consequences of sins. He opines that all human race, Except Jesus and his mother are the heirs of the original sin committed by Adam and Eve. In this way, every human being is born sinful, contaminated by the original. According to this viewpoint, the human race cannot be perceived as naturally innocent or away from intellectual mistake and deviation. Rather, human being and her thoughts and deeds can be understood only based on the doctrine of fall. In addition, the Adam’s original sin in not merely an event but it is a complicated circumstance imposed by God as a punishment of Adam and Eve due to their disobedience which is followed by different types of death as well as such

  4. Epigenetic activation of SIN1 promotes NSCLC cell proliferation and metastasis by affecting the epithelial–mesenchymal transition

    International Nuclear Information System (INIS)

    Hu, Zhongwu; Wang, Yaqin; Wang, Yuemei; Zang, Bao; Hui, Hongxia; You, Zhenbing; Wang, Xiaowei

    2017-01-01

    Stress-activated protein kinase (SAPK) interacting protein 1 (SIN1) is an essential component of mTORC2. Previous studies have shown that SIN1 is a key regulator of Akt pathway which plays an important role in various pathological conditions including cancer. While its effects and mechanisms on the progression of NSCLC remain unknown. In this study, we report that SIN1 is able to promote the growth and migration of NSCLC cells both in vitro and in vivo. Overexpression of SIN1 promoted A549 and H1299 cells proliferation by both MTT and colony formation assays. Consistently, knockdown of SIN1 inhibited the proliferation of these cells. In transwell assay, overexpression of SIN1 increased the migration of A549 and H1299 cells, while SIN1 knockdown reduced their migration. In a tumor xenograft model, overexpression of SIN1 promoted tumor growth of A549 cells in vivo, while SIN1 knockdown suppresses the tumor growth. We also found a mechanistic link between SIN1 and H3K4me3, H3K4me3 is involved in SIN1 upregulation. Moreover, SIN1 can significantly promote the in vitro migration and invasion of NSCLC cells via induction epithelial mesenchymal transition (EMT) process, which subsequently leads to transcriptional downregulation of epithelial marker E-cadherin and upregulation of mesenchymal markers N-cadherin and Vimentin expression. Together, our results reveal that SIN1 plays an important role in NSCLC and SIN1 is a potential biomarker and a promising target in the treatment of NSCLC.

  5. Transformation of a metaphor: semantic shift in a Cantonese term 'Chi Sin' denoting insanity.

    Science.gov (United States)

    Ng, J Y W; Chen, E Y H

    2015-03-01

    The historical evolution of the existing terms used to describe insanity may be able to shed light on the formation of stigma towards psychosis patients. In Hong Kong, a widely used Cantonese term for insanity 'Chi Sin' provides a unique example because of its neutral original sense, as it literally means misconnection in a network circuit. We attempt to trace the origin and subsequent evolution of the term 'Chi Sin' from its early use to the present day to understand how local Hong Kong people have attached increasingly negative connotations to this scientific term since the mid-20th century. We sampled as many newspapers and magazines published in Hong Kong from 1939 to June 2014 as possible, and sampled 7 popular local movies from the 1950s and 1960s. We also searched all the newspapers published in Hong Kong, Macau, Taiwan, and Mainland China from January 1998 to June 2014, and searched several other local historical resources. In one early use of 'Chi Sin' in 1939, the term was only used in a technical sense to describe 'short circuiting'. We found that the development of the telephone system, the Strowger system, in Hong Kong is closely related to the evolution of the semantics of the term 'Chi Sin'. The original meaning of short circuitry of the term 'Chi Sin' is no longer used, and it has become a dead metaphor through repeated use with negative emotional connotations. This illustrates some of the factors facilitating the emergence of a metaphor with subsequent semantic drift.

  6. Fuzzy adaptive integration scheme for low-cost SINS/GPS navigation system

    Science.gov (United States)

    Nourmohammadi, Hossein; Keighobadi, Jafar

    2018-01-01

    Due to weak stand-alone accuracy as well as poor run-to-run stability of micro-electro mechanical system (MEMS)-based inertial sensors, special approaches are required to integrate low-cost strap-down inertial navigation system (SINS) with global positioning system (GPS), particularly in long-term applications. This paper aims to enhance long-term performance of conventional SINS/GPS navigation systems using a fuzzy adaptive integration scheme. The main concept behind the proposed adaptive integration is the good performance of attitude-heading reference system (AHRS) in low-accelerated motions and its degradation in maneuvered or accelerated motions. Depending on vehicle maneuvers, gravity-based attitude angles can be intelligently utilized to improve orientation estimation in the SINS. Knowledge-based fuzzy inference system is developed for decision-making between the AHRS and the SINS according to vehicle maneuvering conditions. Inertial measurements are the main input data of the fuzzy system to determine the maneuvering level during the vehicle motions. Accordingly, appropriate weighting coefficients are produced to combine the SINS/GPS and the AHRS, efficiently. The assessment of the proposed integrated navigation system is conducted via real data in airborne tests.

  7. Total Thyroidectomy

    Directory of Open Access Journals (Sweden)

    Lopez Moris E

    2016-06-01

    Full Text Available Total thyroidectomy is a surgery that removes all the thyroid tissue from the patient. The suspect of cancer in a thyroid nodule is the most frequent indication and it is presume when previous fine needle puncture is positive or a goiter has significant volume increase or symptomes. Less frequent indications are hyperthyroidism when it is refractory to treatment with Iodine 131 or it is contraindicated, and in cases of symptomatic thyroiditis. The thyroid gland has an important anatomic relation whith the inferior laryngeal nerve and the parathyroid glands, for this reason it is imperative to perform extremely meticulous dissection to recognize each one of these elements and ensure their preservation. It is also essential to maintain strict hemostasis, in order to avoid any postoperative bleeding that could lead to a suffocating neck hematoma, feared complication that represents a surgical emergency and endangers the patient’s life.It is essential to run a formal technique, without skipping steps, and maintain prudence and patience that should rule any surgical act.

  8. Síndrome urémico hemolítico asociado a diarrea sin trombocitopenia

    Directory of Open Access Journals (Sweden)

    Alejandro Balestracci

    2017-09-01

    Conclusiones: La prevalencia de SUH D+ sin trombocitopenia fue del 5,6% y la mayoría de los casos fueron leves; sin embargo, el requerimiento de diálisis en uno de ellos señala que la normalización del recuento de plaquetas no siempre es un marcador preciso de resolución de la enfermedad. Nuestros resultados también confirman que el momento de presentación de los pacientes con SUH D+ sin trombocitopenia está usualmente alejado de los primeros síntomas intestinales, por lo que es necesario un alto índice de sospecha diagnóstica.

  9. Production and characterization of Si-N films obtained by r.f. magnetron sputtering

    International Nuclear Information System (INIS)

    Oliveira, A.; Cavaleiro, A.; Vieira, M.T.

    1993-01-01

    Si-N films were deposited by sputtering from an Si 3 N 4 target with different deposition pressures and negative substrate bias. The films were amorphous and showed a ''featureless'' morphology. A high oxygen content was detected in unbiased films. For these films the Si/N ratio was very high compared with the target composition, whereas for biased films the opposite was observed. Si-N films presented cohesive failures for loads as high as 21 N and adhesive failure at 45 N when they were analysed by scratch test. Very high hardness (45 GPa) was obtained, particularly for biased films. Unbiased films were softer, which is attributed to the formation of silicon oxide and/or to a lower compressive stress level. (orig.)

  10. Destroying God's Temple? Physical Inactivity, Poor Diet, Obesity, and Other "Sin" Behaviors.

    Science.gov (United States)

    Faries, Mark D; McClendon, Megan; Jones, Eric J

    2017-02-17

    On average, our participants (N = 112), who self-proclaimed to be Christians, believed that physically inactive lifestyles, unhealthy eating, overeating, and being obese destroy the body, God's temple. However, these beliefs were less definitive, than those of other common "sin" behaviors, such as drug use, smoking, and excessive drinking of alcohol. In addition, destroying the body with physical inactivity or poor diet was not necessarily viewed as sinful. Subsequently, these beliefs did not relate to self-reported physical activity, dietary behavior, or body mass index. It is possible that inactivity, poor dietary habits, and obesity are not internalized into the spiritual perspective as destroying the body, God's temple, in the same way as other "sin" behaviors.

  11. LHCb sensitivity to sin(2$\\beta$) from the CP-asymmetry in B$^0$ $\\rightarrow$ J/$\\psi$($\\mu\\mu$)K$^0_S$($\\pi^+\\pi^-$) decays

    CERN Document Server

    Amato, S; Gandelman, M; Göbel, C; Mangiafave, N; Poss, S; Rodrigues, F

    2009-01-01

    This note presents an update of the B$^0$ $\\rightarrow$ J/$\\psi$($\\mu\\mu$)K$^0_S$($\\pi^+\\pi^-$) analysis in order to obtain the LHCb sensitivity to sin(2$/beta$). We present two selection criteria, one considering only lifetime unbiased cuts and another which includes lifetime biased cuts to reduce further the background contamination. For an integrated luminosity of 2 fb$^-1$ and after L0 trigger, we estimate a yield of 193k events for the B$^0$ $\\rightarrow$ J/$\\psi$($\\mu\\mu$)K$^0_S$ channel with the lifetime unbiased selection criteria, with a total background to signal ration 3.43. For the lifetime biased selection, the signal yield is 208k events and the background to signal ratio is to 0.63. The statistical sensitivity on sin(2$/beta$) is found to be 0.023 and 0.020 for the unbiased and biased selections, respectively.

  12. Sucesos vitales estresantes en mujeres en situación sin hogar

    OpenAIRE

    Vázquez Cabrera, José Juan; Rodríguez Moreno, Sara Isabel; Roca Morales, Pablo; Panadero Herrero, Sonia

    2016-01-01

    Las Personas Sin Hogar (PSH) forman parte de un colectivo especialmente vulnerable al padecimiento de Sucesos Vitales Estresantes (SVE) a lo largo de la vida. Además, los escasos datos indican que las Mujeres Sin Hogar (MSH) presentan una mayor vulnerabilidad a sufrir dichos sucesos. El objetivo de este trabajo es analizar la prevalencia de SVE en un grupo de 138 MSH de la ciudad de Madrid. Los resultados apuntan que las MSH experimentan un número muy elevado de SVE tanto en la infancia/adole...

  13. Moving State Marine SINS Initial Alignment Based on High Degree CKF

    Directory of Open Access Journals (Sweden)

    Yong-Gang Zhang

    2014-01-01

    Full Text Available A new moving state marine initial alignment method of strap-down inertial navigation system (SINS is proposed based on high-degree cubature Kalman filter (CKF, which can capture higher order Taylor expansion terms of nonlinear alignment model than the existing third-degree CKF, unscented Kalman filter and central difference Kalman filter, and improve the accuracy of initial alignment under large heading misalignment angle condition. Simulation results show the efficiency and advantage of the proposed initial alignment method as compared with existing initial alignment methods for the moving state SINS initial alignment with large heading misalignment angle.

  14. Cambios microestructurales y reológicos de masas y panes sin gluten

    OpenAIRE

    Rivera Flores, José Octavio

    2015-01-01

    El estudio de la microestructura de las masas y panes sin gluten nos permite predecir el comportamiento de estos durante los procesos de elaboración y por ende la maquinabilidad de los mismos. Se hizo un análisis reológico de masas sin gluten y un análisis de perfil de textura (TPA) a los panes elaborados a partir de estas, también se tomaron imágenes por medio del microscopio electrónico de barrido, tanto de las masas como de los panes. Para hacer el perfil reológico se hicieron ensayos osci...

  15. Sin City?

    DEFF Research Database (Denmark)

    Svarer, Michael; Gautier, Pieter A.; Teulings, Coen n.

    s moving to the countryside a credible commitment device for couples? We investigate whether lowering the arrival rate of potential alternative partners by moving to a less populated area lowers the dissolution risk for a sample of Danish couples. We find that of the couples who married in the ci......-of-events approach. In addition we use information on father's location as an instrument. We find that the sorting effect dominates. Moving to the countryside is therefore not a cheap way to prolong relationships....

  16. El Palacio sin máscara: La lectura de quien no estuvo allí.

    Directory of Open Access Journals (Sweden)

    Héctor Abad Faciolince

    2008-09-01

    Full Text Available Se trata de un análisis de la obra "El Palacio sin máscara" referido a la toma del Palacio de Justicia por parte de guerrilleros y la masacre ocurrida por parte de los militares. En la obra se retrata la realidad, se poda la información de todo ruido para dejar ver la verdad.

  17. Ten Sins Challenging Education in the Contemporary Global Era: A Philosophical Essay

    Science.gov (United States)

    Sinagatullin, Ilghiz M.

    2004-01-01

    According to this author, the modern epoch is characterized by a decrease of vital spirituality and an increase of materialistic values and virtues. This article discusses what the author views as the ten sins challenging education in the contemporary global era. These are: (1) the shrinking of spiritual values; (2) corruption; (3) sexual…

  18. High precision measurement of sin2theta/sub W/ in semi-leptonic neutrino interactions

    International Nuclear Information System (INIS)

    Guyot, C.

    1985-01-01

    The experiment has provided what is presently the most accurate measurement of sin 2 theta/sub W/. The errors are still too large for a significant test of the standard model and the measured value is in agreement with the measured values of M/sub W/ and M/sub Z/. On the other hand, this result can constrain the Grand Unified models. The standard SU(5) model predicts sin 2 theta/sub W//sup MS/ = 0.214 +/- 0.004 (the error comes from the uncertainty on Lambda/sub MS/), in very good agreement with the measured value. While this model has big problems with the proton lifetime, it could be saved by its supersymmetric extension. In the minimal SU(5) SUSY model (with 2 Higgs supermultiplets) sin 2 theta/sub W//sup MS/ = 0.233 +/- 0.004, [12] in bad agreement with the measured value. The addition of other Higgs supermultiplets increases the value of sin 2 theta/sub W/. Unless some unexpected large contribution from higher-twist terms occurs, the present measurement can already bring a significant constraint on Grand Unified models

  19. Sin$\\phi$ azimuthal asymmetry in semi-inclusive electroproduction on longitudinally polarized nucleon

    CERN Document Server

    Oganessian, K.A.; Bianchi, N.; Kotzinian, A.M.

    1998-01-01

    We investigate the $sin \\phi$ azimuthal asymmetry in the semi-inclusive deep-inelastic lepton scattering off longitudinally polarized nucleon target arising from the time reversal odd structures. The order 1/Q contributions of the leading twist and twist-three distribution and fragmentation functions to that asymmetry for the certain kinematical conditions are numerically estimated.

  20. Decrease in Accuracy of a Rotational SINS Caused by its Rotary Table's Errors

    Directory of Open Access Journals (Sweden)

    Pin Lv

    2014-05-01

    Full Text Available We call a strapdown inertial navigation system (SINS that uses the rotation auto-compensation technique (which is a common method to reduce the effect of the bias errors of inertial components a ‘rotational SINS’. In a rotational SINS, the rotary table is an important component, rotating the inertial sensor assembly back and forth in azimuth to accomplish error modulation. As a consequence of the manufacturing process, errors may exist in rotary tables which decrease the navigation accuracy of rotational SINSs. In this study, the errors of rotary tables are considered in terms of installation error, wobble error and angular error, and the models of these errors are established for the rotational SINS. Next, the propagation characteristics of these errors in the rotational SINS are analysed and their effects on navigation results are discussed. Finally, the theoretical conclusions are tested by numerical simulation. This paper supplies a good reference for the development of low-cost rotational SINSs, which usually have low accuracy rotary tables and which may be used in robots, intelligent vehicles and unmanned aerial vehicles (UAVs.

  1. Do Schacter's Seven Sins of Memory Apply to Ratings of Children's Emotional and Behavioral Functioning?

    Science.gov (United States)

    Renk, Kimberly; Donnelly, Reesa; McKinney, Cliff; Baksh, Elizabeth

    2007-01-01

    Schacter (2001) proposes that there are seven memory malfunctions that occur in everyday life and that affect individuals' ability to recall occurrences in their lives. Given that these sins affect other areas of memory, it is likely that they may affect the ratings that informants provide when they are recalling characteristics of the emotional…

  2. Absolute Absolution: The Forgiveness of Original Sin by Ministers of Government Schooling.

    Science.gov (United States)

    Gatto, John Taylor

    1994-01-01

    Traces the evolution of public schooling as an attempt by progressives and others to absolve citizens of Original Sin and unweave the world view of traditional Christianity. Argues that the removal from schools of Christian beliefs about morality, labor, self-control, and death signals a wish to collectivize the American masses and restore a…

  3. SINs and SOMs: Neural microcircuits for size tuning in the zebrafish and mouse visual pathway.

    Directory of Open Access Journals (Sweden)

    Alison J. Barker

    2013-05-01

    Full Text Available In many animals, a fast and reliable circuit for discriminating between predator-sized objects and edible (prey-sized objects is necessary for survival. How are receptive fields in visual brain areas organized to extract information about size? Recent studies from the zebrafish optic tectum and the mouse visual cortex suggest de novo shaping of receptive fields by subtypes of inhibitory neurons. Del Bene et al. (2010 describe a population of GABAergic neurons in the zebrafish optic tectum (Superficial Interneurons, SINs that are necessary for size filtering during prey capture. Adesnik et al. (2012 describe a somatostatin-expressing interneuron population (SOMs that confers surround suppression on layer II/III pyramidal cells in mouse V1. Strikingly both the SINs and the SOMs, display size-dependent response properties. Increasing visual stimulus size increases excitatory input to these neurons. Dampening SIN or SOM activity alters tuning of neighboring circuits such that they lose preference for small objects. Both results provide exciting evidence for mechanisms of size filtering in visual circuits. Here we review the roles of the SINs and the SOMs and speculate on the similarity of such spatial filters across species.

  4. Construction of Δm2--sin2 2θ plots

    International Nuclear Information System (INIS)

    Snyder, R.

    1991-01-01

    In the two-flavor approximation, the probability for a neutrino to oscillate from one flavor to the other is given by Ρ νa → νb = sin 2 2θ sin 2 (1.27 Δm 2 L/E ν ) where θ is the mixing angle, Δm 2 = |m νa 2 - m νb 2 | is measured in (eV/c 2 ) 2 , L, the distance from the source, is measured in km, and E, the beam energy, is measured in GeV. If either Δm 2 or sin 2 2Θ is zero, there is no oscillation. They might also have small, non-zero values, causing the oscillations to be so small as to be unobservable in a particular experiment. They may also have values which allow us to determine the probability of oscillation, but so far no compelling evidence for oscillation exists. The universal method of portraying what region of parameter space is explored by a neutrino oscillation experiment is to mark off an area on a Δm 2 vs. sin 2 2θ plot. Typically, a line is graphed, with the claim that if the experiment finds not evidence of oscillation, one can, for example, be 90% certain that Δm 2 and sin 2 2θ lie within the region below and to the left of the line. Since these plots are so widely used, it is useful to understand the process by which they are created

  5. SinEx DB: a database for single exon coding sequences in mammalian genomes.

    Science.gov (United States)

    Jorquera, Roddy; Ortiz, Rodrigo; Ossandon, F; Cárdenas, Juan Pablo; Sepúlveda, Rene; González, Carolina; Holmes, David S

    2016-01-01

    Eukaryotic genes are typically interrupted by intragenic, noncoding sequences termed introns. However, some genes lack introns in their coding sequence (CDS) and are generally known as 'single exon genes' (SEGs). In this work, a SEG is defined as a nuclear, protein-coding gene that lacks introns in its CDS. Whereas, many public databases of Eukaryotic multi-exon genes are available, there are only two specialized databases for SEGs. The present work addresses the need for a more extensive and diverse database by creating SinEx DB, a publicly available, searchable database of predicted SEGs from 10 completely sequenced mammalian genomes including human. SinEx DB houses the DNA and protein sequence information of these SEGs and includes their functional predictions (KOG) and the relative distribution of these functions within species. The information is stored in a relational database built with My SQL Server 5.1.33 and the complete dataset of SEG sequences and their functional predictions are available for downloading. SinEx DB can be interrogated by: (i) a browsable phylogenetic schema, (ii) carrying out BLAST searches to the in-house SinEx DB of SEGs and (iii) via an advanced search mode in which the database can be searched by key words and any combination of searches by species and predicted functions. SinEx DB provides a rich source of information for advancing our understanding of the evolution and function of SEGs.Database URL: www.sinex.cl. © The Author(s) 2016. Published by Oxford University Press.

  6. Análisis de costos médicos y resultados de la cirugía coronaria sin circulación extracorpórea

    Directory of Open Access Journals (Sweden)

    Raúl A. Borracci

    2006-01-01

    procedimiento con CEC, y entre $10.100 y $15.300 (mediana = $12.100 para la cirugía “sin bomba”. Este costo mayor estuvo relacionado con el precio del estabilizador descartable, que es comparativamente más caro que el de un oxigenador. Así, proporcionalmente, el costo total de quirófano de una cirugía sin CEC fue el 15% a 39% más caro que la cirugía convencional. Por su parte, el análisis del costo de una cirugía, teniendo en cuenta las tasas de complicaciones, mostró valores entre $11.978 y $18.145 (mediana: $14.350 para la cirugía sin CEC, y entre $12.303 y $16.518 (mediana: $13.377 para el procedimiento “con bomba”. Conclusiones En el presente estudio no se ha podido demostrar una reducción del costo de la cirugía coronaria con el empleo de la técnica de revascularización sin CEC, al compararla con el procedimiento convencional. El precio de los insumos de quirófano (estabilizador coronario parece ser el factor determinante del alto costo de la cirugía sin CEC en la Argentina. Medidas regulativas que contemplen la reutilización de los estabilizadores coronarios descartables o una política que favorezca la reducción del costo de los insumos quirúrgicos podrían mejorar la relación costo-eficacia de la cirugía “sin bomba” en nuestro medio.

  7. Policy recommendations on tacing and reducing program mismatch and perverse incentives present in earmarking sin tax to tobacco growing areas

    Directory of Open Access Journals (Sweden)

    Madeiline Joy Aloria

    2018-03-01

    Full Text Available Background Recognizing that the Philippine 1991 tobacco tax sharing law favoured the development of tobacco, the Sin Tax Law, a separate law on restructuring cigarette tax, expanded the use of such to also cover shifting farmers to viable alternative livelihood. Aside from health-driven supply reduction objectives, this is crucial as evidence shows that tobacco production is continuously declining starting decades ago, requiring to actively shift farmers. Methods Data on tobacco excise tax earmarking and utilization, farmers´ production and shifting behaviours, labor improvement and poverty alleviation indicators, and LGU capacity were analysed to determine potential program mismatches and perverse incentives. Supporting qualitative data were used to identify policy and structural gaps to address these. Results Financing livelihood projects becomes the least priority (only 6% average share i funds, as a result of LGU´s final allocation being determined by their share in total tobacco leaf production, which actually put pressure on their farmers to increase production volume. Meanwhile, infrastructure continue to get bulk of sin tax earmarking and are linked to its political benefits. Last, the provision of cooperative and agro-industrial projects in selected areas were shifting behaviour is heavy can still be improved. Conclusions As the two tobacco tax sharing laws fund both programs to develop tobacco and to shift tobacco farmers to other livelihood, a schizophrenic management exists. Key structural and policy ingredients have to be present to reverse this. First is the need to establish institutional support to manage alternative livelihood funds, in order to balance the powers of National Tobacco Administration over tobacco growing areas. Allocation should not be based on production volume but rather on a systemic or comprehensive welfare assessment of shifted farmers. As livelihood programs are most commonly coursed through civil society

  8. Fixed interface charges between AlGaN barrier and gate stack composed of in situ grown SiN and Al2O3 in AlGaN/GaN high electron mobility transistors with normally off capability

    International Nuclear Information System (INIS)

    Capriotti, M.; Alexewicz, A.; Fleury, C.; Gavagnin, M.; Bethge, O.; Wanzenböck, H. D.; Bertagnolli, E.; Pogany, D.; Strasser, G.; Visalli, D.; Derluyn, J.

    2014-01-01

    Using a generalized extraction method, the fixed charge density N int at the interface between in situ deposited SiN and 5 nm thick AlGaN barrier is evaluated by measurements of threshold voltage V th of an AlGaN/GaN metal insulator semiconductor high electron mobility transistor as a function of SiN thickness. The thickness of the originally deposited 50 nm thick SiN layer is reduced by dry etching. The extracted N int is in the order of the AlGaN polarization charge density. The total removal of the in situ SiN cap leads to a complete depletion of the channel region resulting in V th  = +1 V. Fabrication of a gate stack with Al 2 O 3 as a second cap layer, deposited on top of the in situ SiN, is not introducing additional fixed charges at the SiN/Al 2 O 3 interface

  9. Influence of SST from Pacific and Atlantic Ocean and atmospheric circulation in the precipitation regime of basin from Brazilian SIN

    Science.gov (United States)

    Custodio, M. D.; Ramos, C. G.; Madeira, P.; de Macedo, A. L.

    2013-12-01

    The South American climate presents tropical, subtropical and extratropical features because of its territorial extension, being influenced by a variety of dynamical systems with different spatial and temporal scales which result in different climatic regimes in their subregions. Furthermore, the precipitation regime in South America is influenced by low-frequency phenomena as El Niño-Southern Oscillation (ENSO), the Atlantic dipole and the Madden Julian Oscilation (MJO), in other words, is directly influenced by variations of the Sea Surface Temperature (SST). Due to the importance of the precipitation for many sectors including the planning of productive activities, such as agriculture, livestock and hydropower energy, many studies about climate variations in Brazil have tried to determine and explain the mechanisms that affect the precipitation regime. However, because of complexity of the climate system, and consequently of their impacts on the global precipitation regime, its interactions are not totally understood and therefore misrepresented in numerical models used to forecast climate. The precipitation pattern over hydrographic basin which form the Brasilian National Interconnected System (Sistema Interligado Nacional-SIN) are not yet known and therefore the climate forecast of these regions still presents considerable failure that need to be corrected due to its economic importance. In this context, the purpose here is to determine the precipitation patterns on the Brazilian SIN, based on SST and circulation observed data. In a second phase a forecast climate model for these regions will be produced. In this first moment 30 years (1983 to 2012) of SST over Pacific and Atlantic Ocean were analyzed, along with wind in 850 and 200 hPa and precipitation observed data. The precipitation patterns were analyzed through statistical analyses for interannual (ENSO) and intraseasonal (MJO) anomalies for these variables over the SIN basin. Subsequently, these

  10. Rapid Transfer Alignment of MEMS SINS Based on Adaptive Incremental Kalman Filter.

    Science.gov (United States)

    Chu, Hairong; Sun, Tingting; Zhang, Baiqiang; Zhang, Hongwei; Chen, Yang

    2017-01-14

    In airborne MEMS SINS transfer alignment, the error of MEMS IMU is highly environment-dependent and the parameters of the system model are also uncertain, which may lead to large error and bad convergence of the Kalman filter. In order to solve this problem, an improved adaptive incremental Kalman filter (AIKF) algorithm is proposed. First, the model of SINS transfer alignment is defined based on the "Velocity and Attitude" matching method. Then the detailed algorithm progress of AIKF and its recurrence formulas are presented. The performance and calculation amount of AKF and AIKF are also compared. Finally, a simulation test is designed to verify the accuracy and the rapidity of the AIKF algorithm by comparing it with KF and AKF. The results show that the AIKF algorithm has better estimation accuracy and shorter convergence time, especially for the bias of the gyroscope and the accelerometer, which can meet the accuracy and rapidity requirement of transfer alignment.

  11. Rapid Transfer Alignment of MEMS SINS Based on Adaptive Incremental Kalman Filter

    Directory of Open Access Journals (Sweden)

    Hairong Chu

    2017-01-01

    Full Text Available In airborne MEMS SINS transfer alignment, the error of MEMS IMU is highly environment-dependent and the parameters of the system model are also uncertain, which may lead to large error and bad convergence of the Kalman filter. In order to solve this problem, an improved adaptive incremental Kalman filter (AIKF algorithm is proposed. First, the model of SINS transfer alignment is defined based on the “Velocity and Attitude” matching method. Then the detailed algorithm progress of AIKF and its recurrence formulas are presented. The performance and calculation amount of AKF and AIKF are also compared. Finally, a simulation test is designed to verify the accuracy and the rapidity of the AIKF algorithm by comparing it with KF and AKF. The results show that the AIKF algorithm has better estimation accuracy and shorter convergence time, especially for the bias of the gyroscope and the accelerometer, which can meet the accuracy and rapidity requirement of transfer alignment.

  12. "... As we forgive those who trespass against us...": theological reflections on sin and guilt in the hospital environment.

    Science.gov (United States)

    Schmidt, Kurt W

    2005-08-01

    In general parlance the term sin has lost its existential meaning. Originally a Jewish-Christian term within a purely religious context, referring to a wrongdoing with regard to God, sin has slowly become reduced to guilt in the course of the secularization process. Guilt refers to a wrongdoing, especially with regard to fellow human beings. It also refers to errors of judgement with what can be tragic consequences. These errors can occur whenever human beings are called upon to act, including the hospital environment. A Christian hospital has to address the issue of how to deal not only with guilt-ridden misdemeanors, but also with wrongdoing unto God, which overshadows every instance of guilt-ridden human behavior. Here, as in every parish, the Church Service is the place to acknowledge sin, confess sin, and forgive sin, beyond the boundaries of the parish itself.

  13. Quantum solitons and their relation with fermion fields for the (sin phi)sub(2)-interaction

    International Nuclear Information System (INIS)

    Pogrebkov, A.K.; Sushko, V.N.

    1976-01-01

    Schema of canonical quantization of the/sin phi/sub(2)-self-interaction is developed systematically, which takes into account from the very beginning the existence of solitons in corresponding classical dynamical system. Correct definition of quantum soliton is given. The connection between the descriptions of quantum solitons on the basis of the proposed quantization schema and in terms of fermion fields is demonstrated

  14. DIVERSIDAD DE ABEJAS SIN AGUIJÓN (HYMENOPTERA:MELIPONINI UTILIZADAS EN MELIPONICULTURA EN COLOMBIA

    Directory of Open Access Journals (Sweden)

    Guiomar Nates Parra

    2013-09-01

    Full Text Available En Colombia se conoce la existencia de cerca de 120 especies de abejas nativas sin aguijón, muchas de las cuales tienen importantes usos y representaciones para diversos grupos sociales y culturales. A pesar de que su cría y manejo (meliponicultura, es una actividad que viene creciendo y tecnificándose en Latinoamérica y otras regiones del mundo, sus características y desarrollo en Colombia han sido poco documentados. Se presentan los resultados de entrevistas y visitas a 75 personas en 16 departamentos de Colombia, que cultivan 25 especies de abejas sin aguijón, agrupadas en 12 géneros. Se encontraron al menos nueve especies más sin identificación completa, se reportan cuatro nuevos registros para el país y se amplía la distribución para 21 taxones. Se presenta información sobre la distribución regional y altitudinal, el cultivo urbano y las denominaciones locales para las abejas. Se revisan algunas características de los géneros cultivados más comunes (Tetragonisca, Melipona, Paratrigona, Scaptotrigona, y Nannotrigona y se discute la importancia del vínculo entre diversidad biológica y cultural que se manifiesta en los nombres locales reportados. Ante un escenario mundial de expansión de la meliponicultura, se resaltan necesidades de investigación y riesgos para la conservación y manejo de la diversidad de abejas sin aguijón y los conocimientos asociados.

  15. Escrituras de Oseira (AHN sin relación con este monasterio (S. XI-XVI

    Directory of Open Access Journals (Sweden)

    Romaní Martínez, Miguel

    2005-12-01

    Full Text Available The edition of nine monastic documents never published previously in any form, belonging to the Osera fund, but without any apparent relation to this monastery, increases the knowledge about the referred monasteries.

    La edición de nueve documentos monásticos inéditos pertenecientes al fondo de Oseira, pero sin relación aparente con este monasterio, complementará el conocimiento de los monasterios referidos.

  16. Juan Gelman: Del poeta-legislador a una lengua sin estado

    Directory of Open Access Journals (Sweden)

    Miguel Angel Dalmaroni

    2000-11-01

    Full Text Available La poesía de Gelman transforma el mandato de la tradición de la poesía política con que se inicia su obra, al reemplazarlo por la construcción de una lengua sin estado. La voz de esa tradición se desliza hacia una lengua que problematiza el reconocimiento pero resulta -a la vez- de una disonancia legible, y que se lee en las formas de una voz desalineada respecto de un sujeto, e imaginada como superposición entre figuras que proporcionan, desde el nivel de la representación, orientación constructivas de la escritura e indicación de lectura: el niño; el extranjero sin estado y sin lengua (inmigrante, exiliado, judío, etc.; el estado instable del español literario de la época de la conquista y especialmente el de los místicos; las locas o el loco, el incestuoso. Se propone leer esas figuras como una constelación móvil de confusiones que opera siempre en torno de la identidad: que la toma y la abandona en un movimiento que discute y, a la vez, utiliza las figuras sin estado que ocurren y a un tiempo se sustituyen entre sí. La identidad no resulta negada sino reemplazada cada vez que se le entrega, como en una estrategia momentánea de reposo, el terreno del poema.

  17. Juan Gelman: Del poeta-legislador a una lengua sin estado

    Directory of Open Access Journals (Sweden)

    Miguel Angel Dalmaroni

    2001-11-01

    Full Text Available La poesía de Gelman transforma el mandato de la tradición de la poesía política con que se inicia su obra, al reemplazarlo por la construcción de una lengua sin estado. La voz de esa tradición se desliza hacia una lengua que problematiza el reconocimiento pero resulta -a la vez- de una disonancia legible, y que se lee en las formas de una voz desalineada respecto de un sujeto, e imaginada como superposición entre figuras que proporcionan, desde el nivel de la representación, orientación constructivas de la escritura e indicación de lectura: el niño; el extranjero sin estado y sin lengua (inmigrante, exiliado, judío, etc.; el estado instable del español literario de la época de la conquista y especialmente el de los místicos; las locas o el loco, el incestuoso. Se propone leer esas figuras como una constelación móvil de confusiones que opera siempre en torno de la identidad: que la toma y la abandona en un movimiento que discute y, a la vez, utiliza las figuras sin estado que ocurren y a un tiempo se sustituyen entre sí. La identidad no resulta negada sino reemplazada cada vez que se le entrega, como en una estrategia momentánea de reposo, el terreno del poema.

  18. Recordando a Erlang : un breve paseo (sin esperas) por la Teoría de Colas

    OpenAIRE

    Delgado de la Torre, Rosario

    2009-01-01

    Este artículo tiene un doble objetivo : por una parte, dar cuenta de la celebración del centenario de la Teoría de Colas ; por otra, presentar una breve introducción a lo más clásico de dicha teoría, que pueda resultar de utilidad para aquellos que teniendo unos conocimientos elementales de probabilidad desean introducirse en ella de manera rápida y sin demasiadas complicaciones.

  19. A Fuzzy Adaptive Tightly-Coupled Integration Method for Mobile Target Localization Using SINS/WSN

    Directory of Open Access Journals (Sweden)

    Wei Li

    2016-11-01

    Full Text Available In recent years, mobile target localization for enclosed environments has been a growing interest. In this paper, we have proposed a fuzzy adaptive tightly-coupled integration (FATCI method for positioning and tracking applications using strapdown inertial navigation system (SINS and wireless sensor network (WSN. The wireless signal outage and severe multipath propagation of WSN often influence the accuracy of measured distance and lead to difficulties with the WSN positioning. Note also that the SINS are known for their drifted error over time. Using as a base the well-known loosely-coupled integration method, we have built a tightly-coupled integrated positioning system for SINS/WSN based on the measured distances between anchor nodes and mobile node. The measured distance value of WSN is corrected with a least squares regression (LSR algorithm, with the aim of decreasing the systematic error for measured distance. Additionally, the statistical covariance of measured distance value is used to adjust the observation covariance matrix of a Kalman filter using a fuzzy inference system (FIS, based on the statistical characteristics. Then the tightly-coupled integration model can adaptively adjust the confidence level for measurement according to the different measured accuracies of distance measurements. Hence the FATCI system is achieved using SINS/WSN. This innovative approach is verified in real scenarios. Experimental results show that the proposed positioning system has better accuracy and stability compared with the loosely-coupled and traditional tightly-coupled integration model for WSN short-term failure or normal conditions.

  20. A Chinese Decoction, Kuan-Sin-Yin, Improves Autonomic Function and Cancer-Related Symptoms of Metastatic Colon Cancer.

    Science.gov (United States)

    Chien, Tsai-Ju; Liu, Chia-Yu; Ko, Pin-Hao; Hsu, Chung-Hua

    2016-03-01

    Kuan-Sin-Yin (KSY) is a traditional Chinese medicine (TCM) decoction, which has been shown to have cytostatic effects on cancer cells and involved in the TCM theory of promoting yin-yang balance.Sonce many cancer patients suffer from autonomic dysfunction (AD), which correspond to yin-yang imbalance in TCM. The aim of this study is to evaluate the possible effect of KSY in metastatic colon cancer (mCRC) patients with AD. We conducted a single-group experiment. Total 52 qualified patients were enrolled. Participants took the KSY daily for 2 weeks. The primary outcome was KSY efficacy as reflected in the heart rate variability (HRV) and electrical conductivity (µA) over 12 meridian points. Autonomic function was examined before and after the KSY intervention. The vagal and sympathetic tone were recorded by HRV; 12 meridian energies were measured using a meridian energy analysis device. Secondary outcomes were cancer-related symptoms and patient quality of life (QoL). The results showed that the KSY intervention improved AD via increasing the vagal tone (HF: P = .041), but not the sympathetic tone (LF: P = .154); total autonomic activity was significantly enhanced (HRV activity: P = .013). Intriguingly, energy increased more over the yin meridian (P = .010) than over the yang meridian (P = .015). Cancer-related symptoms and QoL were significantly improved (P yin-yang concept of energy. © The Author(s) 2015.

  1. EVALUACIÓN DE LA CALIDAD DE CARAMELOS DE UCHUVA SIN SACAROSA ADICIONADOS CON CALCIO

    Directory of Open Access Journals (Sweden)

    FRANCIA ELENA VALENCIA G

    Full Text Available Este trabajo evalúa el efecto de la adición de calcio sobre los atributos de calidad de un caramelo blando a base de fruto de uchuva sin sacarosa, comparándolo con uno similar sin calcio. Se emplea calcio lácteo como ingrediente funcional, el cual se incorpora a granel, con el objetivo de alcanzar un valor diario de referencia mayor del 20% en una porción de 15 g de producto, según la normativa colombiana. El calcio afecta principalmente la acidez del producto (, la elasticidad (>, la cohesividad (. El caramelo adicionado presentó contenidos de 292,5 ± 9 mg Ca/porción, correspondiente a un 20 % del valor diario de referencia, lo cual permite identificar al producto con el descriptor 'Excelente fuente de calcio'. Los caramelos blandos de uchuva sin azúcar adicionados con calcio, representan una alternativa económica para cubrir necesidades de calcio en la dieta de la población

  2. A Novel Scheme for DVL-Aided SINS In-Motion Alignment Using UKF Techniques

    Directory of Open Access Journals (Sweden)

    Wenqi Wu

    2013-01-01

    Full Text Available In-motion alignment of Strapdown Inertial Navigation Systems (SINS without any geodetic-frame observations is one of the toughest challenges for Autonomous Underwater Vehicles (AUV. This paper presents a novel scheme for Doppler Velocity Log (DVL aided SINS alignment using Unscented Kalman Filter (UKF which allows large initial misalignments. With the proposed mechanism, a nonlinear SINS error model is presented and the measurement model is derived under the assumption that large misalignments may exist. Since a priori knowledge of the measurement noise covariance is of great importance to robustness of the UKF, the covariance-matching methods widely used in the Adaptive KF (AKF are extended for use in Adaptive UKF (AUKF. Experimental results show that the proposed DVL-aided alignment model is effective with any initial heading errors. The performances of the adaptive filtering methods are evaluated with regards to their parameter estimation stability. Furthermore, it is clearly shown that the measurement noise covariance can be estimated reliably by the adaptive UKF methods and hence improve the performance of the alignment.

  3. Back scattering involving embedded silicon nitride (SiN) nanoparticles for c-Si solar cells

    Science.gov (United States)

    Ghosh, Hemanta; Mitra, Suchismita; Siddiqui, M. S.; Saxena, A. K.; Chaudhuri, Partha; Saha, Hiranmay; Banerjee, Chandan

    2018-04-01

    A novel material, structure and method of synthesis for dielectric light trapping have been presented in this paper. First, the light scattering behaviour of silicon nitride nanoparticles have been theoretically studied in order to find the optimized size for dielectric back scattering by FDTD simulations from Lumerical Inc. The optical results have been used in electrical analysis and thereby, estimate the effect of nanoparticles on efficiency of the solar cells depending on substrate thickness. Experimentally, silicon nitride (SiN) nanoparticles have been formed using hydrogen plasma treatment on SiN layer deposited by Plasma Enhanced Chemical Vapour Deposition (PECVD). The size and area coverage of the nanoparticles were controlled by varying the working pressure, power density and treatment duration. The nanoparticles were integrated with partial rear contact c-Si solar cells as dielectric back reflector structures for the light trapping in thin silicon solar cells. Experimental results revealed the increases of current density by 2.7% in presence of SiN nanoparticles.

  4. Neonatal hyperthyroidism: neonatal clinical course of two brothers born to a mother with Graves-Basedow disease, before and after total thyroidectomy.

    Science.gov (United States)

    Zuppa, A A; Sindico, P; Savarese, I; D'Andrea, V; Fracchiolla, A; Cota, F; Romagnoli, C

    2007-04-01

    About 1-2% of infants born to mothers with Graves' disease or Hashimoto's thyroiditis develop neonatal hyperthyroidism because of transplacental passage of IgG stimulating TSH receptors (TRAb). To evaluate the effect of maternal total thyroidectomy on neonatal clinical course. We describe two brothers born to a mother with Graves' disease, before and after total thyroidectomy. The first child showed persistent tachycardia, the presence of TRAb and a laboratory pattern of hyperthyroidism. Lugol's solution was started and then propylthiouracil was added. Digitalis, furosemide and diazepam were necessary for treatment of heart failure, hypertension and irritability. On the 70th day of life, hormone serum levels normalized and treatment was interrupted. TRAb normalized by the third month of life. The second infant was born 2 years after the mother underwent total thyroidectomy. In spite of a laboratory pattern of hyperthyroidism and positivity to TRAb, he showed only considerable weight loss, and no therapy was required. TRAb may persist after total thyroidectomy: clinical and instrumental follow-up of the newborn is recommended.

  5. Calcium isotopic composition of high-latitude proxy carrier Neogloboquadrina pachyderma (sin.

    Directory of Open Access Journals (Sweden)

    A. Eisenhauer

    2009-01-01

    Full Text Available The accurate reconstruction of sea surface temperature (SST history in climate-sensitive regions (e.g. tropical and polar oceans became a challenging task in palaeoceanographic research. Biogenic shell carbonate SST proxies successfully developed for tropical regions often fail in cool water environments. Their major regional shortcomings and the cryptic diversity now found within the major high latitude proxy carrier Neogloboquadrina pachyderma (sin. highlight an urgent need to explore complementary SST proxies for these cool-water regions. Here we incorporate the genetic component into a calibration study of a new SST proxy for the high latitudes. We found that the calcium isotopic composition (δ44/40Ca of calcite from genotyped net catches and core-top samples of the planktonic foraminifera Neogloboquadrina pachyderma (sin. is related to temperature and unaffected by genetic variations. The temperature sensitivity has been found to be 0.17 (±0.02‰ per 1°C, highlighting its potential for downcore applications in open marine cool-water environments. Our results further indicate that in extreme polar environments, below a critical threshold temperature of 2.0 (±0.5°C associated with salinities below 33.0 (±0.5‰, a prominent shift in biomineralization affects the δ44/40Ca of genotyped and core-top N. pachyderma (sin., becoming insensitive to temperature. These findings highlight the need of more systematic calibration studies on single planktonic foraminiferal species in order to unravel species-specific factors influencing the temperature sensitivity of Ca isotope fractionation and to validate the proxies' applicability.

  6. Test of 10 GHz sin-cosin microwave reflectometer on CASTOR

    International Nuclear Information System (INIS)

    Zacek, F.; Kletecka, P.

    1994-09-01

    The first microwave reflectometric device is described used at the CASTOR tokamak to measure fast density fluctuations. The device operates at the frequency of 10.26 GHz which makes it possible to detect fluctuations near the plasma periphery. The device was proved to work properly during the whole tokamak discharge despite the fact that the reflected signal level varied strongly. The construction of the reflectometric device is described as is its use of the so-called sin-cosin detection system, and the results obtained are discussed. (Z.S.) 8 figs., 3 refs

  7. A precision measurement of sin2θw in neutrino nucleon scattering

    International Nuclear Information System (INIS)

    King, B.J.; Arroyo, C.G.; Bachmann, K.T.; Bazarko, A.O.; Bolton, T.; Foudas, C.; Lefmann, W.C.; Leung, W.C.; Mishra, S.R.; Oltman, E.; Quintas, P.Z.; Rabinowitz, S.A.; Sciulli, F.J.; Seligman, W.G.; Shaevitz, M.H.; Merritt, F.S.; Oreglia, M.J.; Schumm, B.A.; Bernstein, R.H.; Borcherding, F.; Fisk, H.E.; Lamm, M.J.; Marsh, W.; Merritt, K.W.B.; Schellman, H.M.; Yovanovitch, D.D.; Bodek, A.; Budd, H.S.; Barbaro, P. de; Sakumoto, W.K.; Kinnel, T.; Sandler, P.H.; Smith, W.H.

    1993-01-01

    A precise measurement of the weak mixing angle is reported from the ratio of the neutral current to charged current inclusive cross-sections in deep-inelastic neutrino-nucleon scattering. Using the on-shell definition, the value obtained is currently the most accurate determination of sin 2 θ w in a single experiment. The data were gathered at the CCFR neutrino detector in the Fermilab quadrupole-triplet wide-band neutrino beam, with neutrino energies up to 600 GeV. 2 figs., 1 tab., 14 refs

  8. Variables socionutricionales de hogares mazahuas integrados por preescolares desnutridos con madres con obesidad y sin obesidad

    OpenAIRE

    Viridiana Vanessa Conzuelo-González

    2009-01-01

    El primer objetivo fue conocer cuántos menores de cinco años con diferentes grados de desnutrición tienen una madre con sobrepeso/obesidad/ en una comunidad indígena que vive en extrema pobreza y bajo condiciones de migración masculina internacional. El segundo fue comparar tres variables socionutricionales (ingreso familiar, educación de la madre y adecuación nutrimental de la dieta diaria) entre estos hogares y los hogares con desnutrición infantil y madres sin obesidad. Se realizó un estud...

  9. Measurement of sin2β in Tree Dominated B0 Decays and Ambiguity Removal

    International Nuclear Information System (INIS)

    Lacker, H.

    2007-01-01

    The most recent results from the B-factories on the time-dependent CP asymmetries measured in B 0 -decays mediated by b→cc-bar s quark-transitions are reviewed. The Standard Model interpretation of the results in terms of the parameter sin2β leads to a four-fold ambiguity on the unitarity triangle β which can be reduced to a two-fold ambiguity by measuring the sign of the parameter cos2β. The results on cos2β obtained so far are reviewed

  10. Del fin de la guerra fria al comienzo de la guerra sin fin

    OpenAIRE

    Ferrier, Jean Pierre

    2006-01-01

    El Profesor Ferrier nos describe los acontecimientos de la sociedad internacional en los ultimos 15 años y señala la profunda diferencia entre "la estabilidad" durante la guerra fría y la "revolucion" que se ha producido en el escenario internacional a partir de la caida del muro de Berlin. Hace especial referencia al comportamiento de la superpotencia (Estados Unidos) y su guerra sin fin contra los "nuevos enemigos" en los diferentes teatros internacionales en su lucha por imponer el "Bien" ...

  11. Superconducting ring magnets of the PIOTRON Pi-meson therapy facility at SIN

    Energy Technology Data Exchange (ETDEWEB)

    Maix, R K; Meyer, G; Roman, T; Horvath, I; Vecsey, G; Zellweger, J

    1982-01-01

    Negative Pi-mesons seem to be very promising for cancer therapy, because of their well defined penetration depth and their enhanced energy deposition in the absorption region. A prototype Pi-meson therapy facility, called PIOTRON, has been constructed at SIN, where also pion beams of sufficient intensity are available. The central part of this system are two ring magnets, consisting each of 60 superconducting flat coils, with the aid of which 60 pion beams can be guided around a heavy iron shield and focused on the patient. In this paper the fabrication and the initial operation of these magnets is discussed.

  12. Sarcoidosis aguda: Variante de Síndrome de Löfgren sin eritema nodoso

    OpenAIRE

    Pérez, Gerardo; Facal, Jorge

    2014-01-01

    El síndrome de Löfgren, es una variante aguda de la sarcoidosis, que se caracteriza por fiebre, eritema nodoso, adenomegalias hiliares pulmonares y artritis. En general, tiene un curso benigno y autolimitado, que contrasta con las formas crónicas que requieren uso de corticoides y tienen tendencia a la recidiva. Se describe aquí el caso clínico de un paciente joven, de sexo masculino, con artritis pero sin eritema nodoso, lo que dificultó el planteo diagnóstico de síndrome de Löfgren. Se real...

  13. Diversidad de sistemas planetarios sin gigantes gaseosos en discos de baja masa

    OpenAIRE

    Ronco, María Paula

    2013-01-01

    Como indica el título de esta tesis, el objetivo general de nuestro trabajo es poder analizar la diversidad de sistemas planetarios que podrían formarse alrededor de estrellas de tipo solar y sin gigantes gaseosos. Nuestro interés particular es estudiar estos sistemas en discos de baja masa, pues podemos asegurar que en ellos no hay posibilidad de formar planetas gigantes gaseosos. Para poder lograr este análisis desarrollamos simulaciones de N-cuerpos orientadas a estudiar el proceso de form...

  14. [Successful treatment of surgically induced necrotizing sclerokeratitis (SINS) with systemic immunosuppresive agents and amniotic membrane grafting].

    Science.gov (United States)

    Cordero-Coma, M; Franco-Benito, M; García-Ruiz-de-Morales, J M; Alonso-Orcajo, N; Del Barrio-Manso, I

    2009-11-01

    We report the case of a 74-year-old female who developed a necrotizing sclerokeratitis affecting her left eye after uncomplicated cataract surgery. She had no previous history of systemic autoimmune disease. Histopathology of the lesion revealed necrotic granulomatosis with an increased number of plasma cells. Surgically induced necrotizing sclerokeratitis (SINS) is a serious entity which requires prompt and aggressive therapy to prevent its potential devastating ocular consequences. Conjunctival resection and amniotic membrane grafting may be necessary to temporarily interrupt local immunologic events in severe cases. However, associated systemic immunomodulatory therapy seems to be mandatory (Arch Soc Esp Oftalmol 2009; 84: 577-580).

  15. Clima organizacional y disposici?n al cambio en una entidad sin ?nimo de lucro

    OpenAIRE

    G?nzalez-Rubio, Daniella; Quintanilla, Karen

    2017-01-01

    El prop?sito de la investigaci?n fue describir el clima organizacional y la actitud hacia el cambio de los colaboradores de la Fundaci?n Compasi?n y Amor, entidad sin ?nimo de lucro, con el fin de generar una propuesta que contribuya al desarrollo organizacional. Se realiz? una investigaci?n cuantitativa y descriptiva con 15 colaboradores de la Fundaci?n, los que tienen contrato directo y est?n en cargo administrativo y los voluntarios que no tienen contrato. Se dise?? y aplic? una bater?a c...

  16. «El castigo sin venganza», a la conquista del repertorio

    OpenAIRE

    Mancebo Salvador, Yolanda

    2018-01-01

    El artículo da cuenta de todos los montajes de El castigo sin venganza de Lope de Vega, desde su estreno en 1632 hasta 2014, tanto en España como en el extranjero. Se recogen las representaciones de la pieza en el ámbito profesional y en el escolar, con especial atención a los espectáculos de las escuelas de arte escénico (ESAD) y de las universidades. Se analizan los signos que intervinieron en las más destacadas puestas en escena desde el reparto a la escenografía, vestuario, música, versió...

  17. Alteraciones emocionales en la enfermedad de Parkinson idiopático sin demencia

    OpenAIRE

    Hurtado González, Carlos Alberto

    2014-01-01

    [ES]Actualmente la enfermedad de Parkinson ha comenzado a ser considerada como una patología de carácter neuroconductual cognitivo que se encuentra relacionada con alteraciones emocionales como la depresión, ansiedad y apatía que contribuyen a desmejorar la calidad de vida de los pacientes que padecen esta enfermedad. El objetivo de este trabajo tiene como propósito estudiar y analizar las alteraciones emocionales (depresión, ansiedad y apatía) en pacientes con EP sin demencia en est...

  18. Pájaros enjaulados: homosexualidad y prisión en Hombres sin mujer

    OpenAIRE

    Gallardo Saborido, Emilio José

    2010-01-01

    Este artículo se centra en la interacción entre homosexualidad y prisión en la novela del cubano Carlos Montenegro titulada “Hombres sin mujer” (1938). A partir de una aproximación sociológica al hecho literario, se analizan estructuralmente las nociones y prácticas homosexuales carcelarias, teniendo en cuenta especialmente sus componentes y la creación de categorías auto-explicativas o etnocategorías, el orden en el que se constituyen estos elementos y los conflictos que los a...

  19. Variables socionutricionales de hogares mazahuas integrados por preescolares desnutridos con madres con obesidad y sin obesidad

    OpenAIRE

    Viridiana Vanessa Conzuelo-González; Ivonne Vizcarra-Bordi

    2009-01-01

    El primer objetivo fue conocer cuántos menores de cinco años con diferentes grados de desnutrición tienen una madre con sobrepeso/obesidad/ en una comunidad indígena que vive en extrema pobreza y bajo condiciones de migración masculina internacional. El segundo fue comparar tres variables socionutricionales (ingreso familiar, educación de la madre y adecuación nutrimental de la dieta diaria) entre estos hogares y los hogares con desnutrición infantil y madres sin obesidad. Se realizó un est...

  20. Los Estados Unidos de Obama: entre el idealismo y el regreso al containment sin enemigo global

    Directory of Open Access Journals (Sweden)

    Ricardo García Duarte

    2009-11-01

    Full Text Available El ascenso de Obama al poder representaba, sin duda, un cambio radical en relación con la política internacional desplegada por el presidente George W. Bush y su doctrina sobre la guerra preventiva. En una perspectiva de más largo plazo podría, además, significar un giro hacia el idealismo después de un largo período de predominio del realismo, muy intensamente desarrollado durante la guerra fría, mediante la doctrina del containment. La prevalencia de la diplomacia y la restitución del

  1. MODIS/Aqua Land Surface Temperature/3-Band Emissivity Daily L3 Global 1km SIN Grid Day V006

    Data.gov (United States)

    National Aeronautics and Space Administration — MODIS/Aqua Land Surface Temperature/3-Band Emissivity Daily L3 Global 1km SIN Grid Day (MYD21A1D.006). A new suite of MODIS Land Surface Temperature (LST) and...

  2. MODIS/Terra Land Surface Temperature/3-Band Emissivity Daily L3 Global 1km SIN Grid Night V006

    Data.gov (United States)

    National Aeronautics and Space Administration — MODIS/Terra Land Surface Temperature/3-Band Emissivity Daily L3 Global 1km SIN Grid Night (MOD21A1N.006). A new suite of MODIS Land Surface Temperature (LST) and...

  3. MODIS/Aqua Land Surface Temperature/3-Band Emissivity Daily L3 Global 1km SIN Grid Night V006

    Data.gov (United States)

    National Aeronautics and Space Administration — MODIS/Aqua Land Surface Temperature/3-Band Emissivity Daily L3 Global 1km SIN Grid Night (MYD21A1N.006). A new suite of MODIS Land Surface Temperature (LST) and...

  4. MODIS/Terra Land Surface Temperature/3-Band Emissivity Daily L3 Global 1km SIN Grid Day V006

    Data.gov (United States)

    National Aeronautics and Space Administration — MODIS/Terra Land Surface Temperature/3-Band Emissivity Daily L3 Global 1km SIN Grid Day (MOD21A1D.006). A new suite of MODIS Land Surface Temperature (LST) and...

  5. A structured workflow for mapping human Sin3 histone deacetylase complex interactions using Halo-MudPIT AP-MS.

    Science.gov (United States)

    Banks, Charles A S; Thornton, Janet L; Eubanks, Cassandra G; Adams, Mark K; Miah, Sayem; Boanca, Gina; Liu, Xingyu; Katt, Maria; Parmely, Tari; Florens, Laurence A; Washburn, Michael P

    2018-03-29

    Although a variety of affinity purification mass spectrometry (AP-MS) strategies have been used to investigate complex interactions, many of these are susceptible to artifacts due to substantial overexpression of the exogenously expressed bait protein. Here we present a logical and systematic workflow that uses the multifunctional Halo tag to assess the correct localization and behavior of tagged subunits of the Sin3 histone deacetylase complex prior to further AP-MS analysis. Using this workflow, we modified our tagging/expression strategy with 21.7% of the tagged bait proteins that we constructed, allowing us to quickly develop validated reagents. Specifically, we apply the workflow to map interactions between stably expressed versions of the Sin3 subunits SUDS3, SAP30 or SAP30L and other cellular proteins.  Here we show that the SAP30 and SAP30L paralogues strongly associate with the core Sin3 complex, but SAP30L has unique associations with the proteasome and the myelin sheath.  Next, we demonstrate an advancement of the complex NSAF (cNSAF) approach, in which normalization to the scaffold protein SIN3A accounts for variations in the proportion of each bait capturing Sin3 complexes and allows a comparison between different baits capturing the same protein complex. This analysis reveals that although the Sin3 subunit SUDS3 appears to be used in both SIN3A and SIN3B based complexes, the SAP30 subunit is not used in SIN3B based complexes. Intriguingly, we do not detect the Sin3 subunits SAP18 and SAP25 among the 128 high-confidence interactions identified, suggesting that these subunits may not be common to all versions of the Sin3 complex in human cells. This workflow provides the framework for building validated reagents to assemble quantitative interaction networks for chromatin remodeling complexes and provides novel insights into focused protein interaction networks. Published under license by The American Society for Biochemistry and Molecular Biology, Inc.

  6. Sobredentadura total superior implantosoportada Superior total overdenture on implants

    Directory of Open Access Journals (Sweden)

    Luis Orlando Rodríguez García

    2010-06-01

    Full Text Available Se presenta un caso de un paciente desdentado total superior, rehabilitado en la consulta de implantología de la Clínica "Pedro Ortiz" del municipio Habana del Este en Ciudad de La Habana, Cuba, en el año 2009, mediante prótesis sobre implantes osteointegrados, técnica que se ha incorporado a la práctica estomatológica en Cuba como alternativa al tratamiento convencional en los pacientes desdentados totales. Se siguió un protocolo que comprendió una fase quirúrgica, procedimiento con o sin realización de colgajo y carga precoz o inmediata. Se presenta un paciente masculino de 56 años de edad, que acudió a la consulta multidisciplinaria, preocupado, porque se le habían elaborado tres prótesis en los últimos dos años y ninguna reunía los requisitos de retención que él necesitaba para sentirse seguro y cómodo con las mismas. El resultado final fue la satisfacción total del paciente, con el mejoramiento de la calidad estética y funcional.This is the case of a total maxilla edentulous patient seen in consultation of the "Pedro Ortíz" Clinic Implant of Habana del Este municipality in 2009 and con rehabilitation by prosthesis over osteointegration implants added to stomatology practice in Cuba as an alternative to conventional treatment in patients totally edentulous. We follow a protocol including a surgery or surgical phase, technique without or with flap creation and early or immediate load. This is a male patient aged 56 came to our multidisciplinary consultation worried because he had three prostheses in last two years and any fulfilled the requirements of retention to feel safe and comfortable with prostheses. The final result was the total satisfaction of rehabilitated patient improving its aesthetic and functional quality.

  7. Demo 94. Campana de vacío : hinchar un globo sin soplar y cocer un huevo en el Everest

    OpenAIRE

    Garro Martínez, Núria

    2013-01-01

    Objetivo: a) Hinchar un globo sin soplar: Experimentar la relación entre el volumen y la presión de los gases. Demostrar que es posible hinchar un globo sin insuflar aire en su interior, reduciendo la presión (atmosférica). b) Cocer un huevo en el Everest: Comprobar la disminución del punto de ebullición del agua al reducir la presión (atmosférica)

  8. A Study of Large sin2φBs with High Mass Fourth Generation t'

    International Nuclear Information System (INIS)

    Ma Chien Yi

    2009-01-01

    The Standard Model predicts the CP violation phase φ SM Bs -M 12 ≅ (V * ts V tb ) in B s (bar) B s mixing is very small, of O(λ 2 η) ∼ -0.02, any finite value of φ Bs measured at the Tevatron would mean New Physics. Recent hints for finite sin2φ Bs have appeared from CDF and D 0 experiments at the Tevatron Run II. We consider the possibility to account for it with the 4 th generation t' quark. Considering recent direct search bounds, we set the mass to be near the unitarity bound of 600 GeV. Combining the measurement values of Δm Bs with B(B d → X s l + l - , together with typical f Bs values, we find a sizable sin2φ SM4 B s ∼ -0.3. Using a typical value of m b' = 580 GeV, we get a narrow range of values, 0.089 t'b | + → π + ν(bar)ν) and Δm D 0. Finally, we use the ZFITTER code to check the global fit deviation. (author)

  9. An SINS/GNSS Ground Vehicle Gravimetry Test Based on SGA-WZ02

    Directory of Open Access Journals (Sweden)

    Ruihang Yu

    2015-09-01

    Full Text Available In March 2015, a ground vehicle gravimetry test was implemented in eastern Changsha to assess the repeatability and accuracy of ground vehicle SINS/GNSS gravimeter—SGA-WZ02. The gravity system developed by NUDT consisted of a Strapdown Inertial Navigation System (SINS, a Global Navigation Satellite System (GNSS remote station on test vehicle, a GNSS static master station on the ground, and a data logging subsystem. A south-north profile of 35 km along the highway in eastern Changsha was chosen and four repeated available measure lines were obtained. The average speed of a vehicle is 40 km/h. To assess the external ground gravity disturbances, precise ground gravity data was built by CG-5 precise gravimeter as the reference. Under relative smooth conditions, internal accuracy among repeated lines shows an average agreement at the level of 1.86 mGal for half wavelengths about 1.1 km, and 1.22 mGal for 1.7 km. The root-mean-square (RMS of difference between calculated gravity data and reference data is about 2.27 mGal/1.1 km, and 1.74 mGal/1.7 km. Not all of the noises caused by vehicle itself and experiments environments were eliminated in the primary results. By means of selecting reasonable filters and improving the GNSS observation conditions, further developments in ground vehicle gravimetry are promising.

  10. SinCHet: a MATLAB toolbox for single cell heterogeneity analysis in cancer.

    Science.gov (United States)

    Li, Jiannong; Smalley, Inna; Schell, Michael J; Smalley, Keiran S M; Chen, Y Ann

    2017-09-15

    Single-cell technologies allow characterization of transcriptomes and epigenomes for individual cells under different conditions and provide unprecedented resolution for researchers to investigate cellular heterogeneity in cancer. The SinCHet ( gle ell erogeneity) toolbox is developed in MATLAB and has a graphical user interface (GUI) for visualization and user interaction. It analyzes both continuous (e.g. mRNA expression) and binary omics data (e.g. discretized methylation data). The toolbox does not only quantify cellular heterogeneity using S hannon P rofile (SP) at different clonal resolutions but also detects heterogeneity differences using a D statistic between two populations. It is defined as the area under the P rofile of S hannon D ifference (PSD). This flexible tool provides a default clonal resolution using the change point of PSD detected by multivariate adaptive regression splines model; it also allows user-defined clonal resolutions for further investigation. This tool provides insights into emerging or disappearing clones between conditions, and enables the prioritization of biomarkers for follow-up experiments based on heterogeneity or marker differences between and/or within cell populations. The SinCHet software is freely available for non-profit academic use. The source code, example datasets, and the compiled package are available at http://labpages2.moffitt.org/chen/software/ . ann.chen@moffitt.org. Supplementary data are available at Bioinformatics online. © The Author(s) 2017. Published by Oxford University Press.

  11. Preparation and combustion of coal-water fuel from the Sin Pun coal deposit, southern Thailand

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-05-01

    In response to an inquiry by the Department of Mineral Resources in Thailand, the Energy & Environmental Research Center (EERC) prepared a program to assess the responsiveness of Sin Pun lignite to the temperature and pressure conditions of hot-water drying. The results indicate that drying made several improvements in the coal, notably increases in heating value and carbon content and reductions in equilibrium moisture and oxygen content. The equilibrium moisture content decreased from 27 wt% for the raw coal to about 15 wt% for the hot-water-dried (HWD) coals. The energy density for a pumpable coal-water fuel (CWF) indicates an increase from 4500 to 6100 Btu/lb by hot-water drying. Approximately 650 lb of HWD Sin Pun CWF were fired in the EERC`s combustion test facility. The fuel burned extremely well, with no feed problems noted during the course of the test. Fouling and slagging deposits each indicated a very low rate of ash deposition, with only a dusty layer formed on the cooled metal surfaces. The combustor was operated at between 20% and 25% excess air, resulting in a flue gas SO{sub 2} concentration averaging approximately 6500 parts per million.

  12. Sin práctica no hay discurso, sin cuerpo no hay saber: Sobre legitimidades en las teorías de la descolonización

    Directory of Open Access Journals (Sweden)

    Maria Ximena Postigo

    2016-03-01

    En todo proceso de descolonización del saber, tan importante como la afirmación de una autonomía epistemológica y práctica es el reconocimiento del lugar de enunciación desde el que esta se produce. Una teoría de la descolonización elaborada desde la observación de los movimientos sociales no es semejante a una producida desde el propio movimiento social. En el primer caso, la teoría de lo de-colonial no deriva ni nace de una práctica. Walter Mignolo, por ejemplo, quien define su propuesta teórica como “la intervención de un pensador de-colonial”, escribe desde este lugar. En el segundo caso, la teoría se piensa desde y para el movimiento de los cuerpos. Así, Silvia Rivera Cusicanqui –para quien postulados como los de Mignolo dan cuenta de otra forma de colonialismo­– sostiene que un pensamiento de la descolonización es inimaginable sin una práctica descoloniozadora. En este contexto interno-externo, una mirada al Estado Plurinacional desde intervenciones como las de Mignolo tiende a una idealización binaria que no contribuye al proceso descolonizador sino, más bien, a una rearticulación del pensamiento occidental. A su vez, esta idealización es desmentida por discursos internos que ven en el gobierno de Evo Morales una incoherencia entre el discurso y la práctica. Este artículo explora todas estas instancias, reconociendo en las teorías producidas desde la lucha los pilares del Estado Plurinacional, y en las tensiones entre poderosos aquello que más bien, oscurece el valor del movimiento social.

  13. Geochemical distribution of harmful elements in top soils of an Italian National Interest Area (S.I.N.): the Domizio-Flegreo Littoral and Agro Aversano case study

    Science.gov (United States)

    Bove, M.; Grezzi, G.; Albanese, S.; de Vivo, B.; Lima, A.

    2009-04-01

    The Domizio-Flegreo Littoral and Agro Aversano area has been classified by the Italian Ministry of Environment (Italian Ministero dell'Ambiente e della Tutela del Territorio e del Mare) as a S.I.N. (Sito di Interesse Nazionale, L. 426/98 - Decreto 10 Gennaio 2000 - G.U. 29/5/01). In this category have been included all those contaminated lands that, both for their extension and their historical and present land use, are considered to be particularly harmful for human health. In Italy have been selected a total of 54 S.I.N.; among all of these, the Domizio-Flegreo Littoral and Agro Aversano S.I.N. is one of the widest (1564 Km2). The study area is located in north-western Campania region, from the Avella Mountain to the coastline, and from the Campi Flegrei area to the northern boundaries between Campania and Latium Regions. It includes a total of 77 towns from both Naples and Caserta provinces. The Domizio-Flegreo Littoral and Agro Aversano S.I.N. is characterized by a strongly urbanization in its internal portions, and by intensive agricultural activities in its northern and coastal portions. During past years this wide area has been the set of an unknown number of illegal activities controlled by the organized crime, including toxic waste disposal of unknown sources from different Regions of Italy, unauthorized building, intensive uncontrolled agricultural practices and so on. Part of these environmental crimes have been and are under investigations by Italian Authorities. For a geochemical characterization of this contaminated land, between May 2006 and January 2008, a total of 292 (179 in the Litorale Domizio-Flegreo and 113 in the Agro Aversano) top soils (5-15 cm depth) have been collected, with a sampling density of about 1 sample/5 Km2. The GIS™ and a new Multifractal Inverse Distance Weighted (MIDW) (Cheng 1999 a; b) method available in the software GeoDAS™ (Cheng, 2003; Lima et al., 2003) interpolated maps have been obtained. The latter are overlaid

  14. Expression Analysis of p16, c-Myc, and mSin3A in Non-small Cell Lung Cancer by Computer Aided Scoring and Analysis (CASA).

    Science.gov (United States)

    Salmaninejad, Arash; Estiar, Mehrdad Asghari; Gill, Rajbir K; Shih, Joanna H; Hewitt, Stephen; Jeon, Hyo-Sung; Fukuoka, Junya; Shilo, Konstantin; Shakoori, Abbas; Jen, Jin

    2015-01-01

    Immunohistochemical analysis (IHC) of tissue microarray (TMA) slides enables large sets of tissue samples to be analyzed simultaneously on a single slide. However, manual evaluation of small cores on a TMA slide is time consuming and error prone. We describe a computer aided scoring and analysis (CASA) method to allow facile and reliable scoring of IHC staining using TMA containing 300 non-small cell lung cancer (NSCLC) cases. In the two previous published papers utilizing our TMA slides of lung cancer we examined 18 proteins involved in the chromatin machinery. We developed our study using more proteins of the chromatin complex and several transcription factors that facilitate the chromatin machinery. Then, a total of 78 antibodies were evaluated by CASA to derive a normalized intensity value that correlated with the overall staining status of the targeting protein. The intensity values for TMA cores were then examined for association to clinical variables and predictive significance individually and with other factors. RESULTs: Using our TMA, the intensity of several protein pairs were significantly correlated with an increased risk of death in NSCLC. These included c-Myc with p16, mSin3A with p16 and c-Myc with mSinA. Predictive values of these pairs remained significant when evaluated based on standard IHC scores. Our results demonstrate the usefulness of CASA as a valuable tool for systematic assessment of TMA slides to identify potential predictive biomarkers using a large set of primary human tissues.

  15. El problema del crecimiento sostenible ¿cómo crecer sin destruirse?

    Directory of Open Access Journals (Sweden)

    Jorge Saravia Rios

    2010-08-01

    Full Text Available De una u otra forma las organizaciones perciben el crecer como una meta necesaria en la planeación estratégica y cuando se logra el crecimiento buscado se supone una gestión exitosa. Sin embargo, en ocasiones no hay claridad sobre lo que significa crecer, cuáles son sus efectos y no se comprende con profundidad el significado de una buena gestión. Es común ver a las organizaciones formular preguntas como:¿Crecer significa vender más?, ¿Hasta dónde puedo crecer? ¿Crecer es tener mayor infraestructura y personal? ¿Qué tan rentable seré creciendo? o presentando afirmaciones como: “la meta del plan estratégico para este año es crecer un 20%, eso nos posicionará como el número uno en el sector”. La meta de una organización debe ser: ser sostenible y el crecer, puede ser una estrategia para lograrla, sin embargo, el crecer por sí mismo no necesariamente genera sostenibilidad, por esto, si una organización lo entiende como su meta puede comprometer su viabilidad. El problema del crecimiento tiene varias dimensiones de análisis que involucran todas las instancias de una organización, por ejemplo, se necesita tener acceso a la información del mercado y el entorno, se necesita tener la inteligencia para comprender esta información, se necesita una estructura organizacional dinámica, flexible e innovadora, es necesario comprender cómo los diferentes procesos interactúan y qué recursos necesitan. Para entender el crecer como una estrategia, se hace necesaria su formalización, y el uso de herramientas que permitan su manejo, estas herramientas deberán incluir las diferentes dimensiones de análisis. Mediante el uso de estos modelos, una organización puede diseñar una estrategia de crecimiento coherente con sus metas, y sin el riesgo de comprometer su estabilidad.

  16. Dual Regulation of Bacillus subtilis kinB Gene Encoding a Sporulation Trigger by SinR through Transcription Repression and Positive Stringent Transcription Control.

    Science.gov (United States)

    Fujita, Yasutaro; Ogura, Mitsuo; Nii, Satomi; Hirooka, Kazutake

    2017-01-01

    It is known that transcription of kinB encoding a trigger for Bacillus subtilis sporulation is under repression by SinR, a master repressor of biofilm formation, and under positive stringent transcription control depending on the adenine species at the transcription initiation nucleotide (nt). Deletion and base substitution analyses of the kinB promoter (P kinB ) region using lacZ fusions indicated that either a 5-nt deletion (Δ5, nt -61/-57, +1 is the transcription initiation nt) or the substitution of G at nt -45 with A (G-45A) relieved kinB repression. Thus, we found a pair of SinR-binding consensus sequences (GTTCTYT; Y is T or C) in an inverted orientation (SinR-1) between nt -57/-42, which is most likely a SinR-binding site for kinB repression. This relief from SinR repression likely requires SinI, an antagonist of SinR. Surprisingly, we found that SinR is essential for positive stringent transcription control of P kinB . Electrophoretic mobility shift assay (EMSA) analysis indicated that SinR bound not only to SinR-1 but also to SinR-2 (nt -29/-8) consisting of another pair of SinR consensus sequences in a tandem repeat arrangement; the two sequences partially overlap the '-35' and '-10' regions of P kinB . Introduction of base substitutions (T-27C C-26T) in the upstream consensus sequence of SinR-2 affected positive stringent transcription control of P kinB , suggesting that SinR binding to SinR-2 likely causes this positive control. EMSA also implied that RNA polymerase and SinR are possibly bound together to SinR-2 to form a transcription initiation complex for kinB transcription. Thus, it was suggested in this work that derepression of kinB from SinR repression by SinI induced by Spo0A∼P and occurrence of SinR-dependent positive stringent transcription control of kinB might induce effective sporulation cooperatively, implying an intimate interplay by stringent response, sporulation, and biofilm formation.

  17. Research on the Strategy of Motion Constraint-Aided ZUPT for the SINS Positioning System of a Shearer

    Directory of Open Access Journals (Sweden)

    Hai Yang

    2017-11-01

    Full Text Available The accurate measurement of position and orientation for shearers is a key technology in realizing an automated, fully-mechanized, coal mining face. Since Global Positioning System (GPS signal cannot arrive at the coal mine underground, wireless sensor network positioning system cannot operate stably in the coal mine; thus a strap-down inertial navigation system (SINS is used to measure the position and orientation of the shearer. Aiming at the problem of the SINS accumulative error, this paper proposes a positioning error correction method based on the motion constraint-aided SINS zero velocity updated (ZUPT model. First of all, a stationary state detection model of the shearer is built with median filter based on the acceleration and angular rate measured by the SINS. Secondly, the motion of the shearer is analyzed using coal mining technology, then the motion constraint model of the shearer is established. In addition, the alternate action between the motion constraint model and the ZUPT model is analyzed at the process of movement and cessation of the shearer, respectively; hence, the motion constraint-aided SINS ZUPT model is built. Finally, by means of the experimental platform of the SINS for the shearer, the experimental results show that the maximum position error with the positioning model proposed in this paper is 1.6 m in 180 s, and increases by 92.0% and 88.1% compared with the single motion constraint model and single ZUPT model, respectively. It can then restrain the accumulative error of the SINS effectively.

  18. Threshold stoichiometry for beam induced nitrogen depletion of SiN

    International Nuclear Information System (INIS)

    Timmers, H.; Weijers, T.D.M.; Elliman, R.G.; Uribasterra, J.; Whitlow, H.J.; Sarwe, E.-L.

    2002-01-01

    Measurements of the stoichiometry of silicon nitride films as a function of the number of incident ions using heavy ion elastic recoil detection (ERD) show that beam-induced nitrogen depletion depends on the projectile species, the beam energy, and the initial stoichiometry. A threshold stoichiometry exists in the range 1.3>N/Si≥1, below which the films are stable against nitrogen depletion. Above this threshold, depletion is essentially linear with incident fluence. The depletion rate correlates non-linearly with the electronic energy loss of the projectile ion in the film. Sufficiently long exposure of nitrogen-rich films renders the mechanism, which prevents depletion of nitrogen-poor films, ineffective. Compromising depth-resolution, nitrogen depletion from SiN films during ERD analysis can be reduced significantly by using projectile beams with low atomic numbers

  19. Cost of global warming may be 'sin' taxes on CO 2 use

    International Nuclear Information System (INIS)

    Nilson, Cliff.

    1995-01-01

    One suggested solution for curbing carbon dioxide emissions and thus stopping the so-called greenhouse effect is taxing the emissions. A meeting in Maastrict, The Netherlands, The Intergovernmental Panel on Climate Change declared that greenhouse emissions are putting the worlds climate at serious risk. The panel called on both industry and governments to act 'urgently' to deal with the threat. For some who have been watching world temperature closely, all of this concern may seem a bit strange. Worldwide temperatures had cooled by approximately 0.08 degrees Fahrenheit in the five years between 1987 and 1992, perhaps the strongest arguments for global warming come from surface temperature measurement, taken primarily at weather stations, show a steady march toward warmer temperatures since 1980 or so. Despite the satellite record and other evidence that nothing of global warming are yet appearing CO 2 sin taxes seem a likely possibility in at least some European countries and perhaps in Canada. (author)

  20. LA ESFERA AFECTIVA EN LA EDUCACIÓN DE LOS MENORES SIN AMPARO FAMILIAR

    Directory of Open Access Journals (Sweden)

    Alybé Moreno-Aurioles Matamoros

    2014-09-01

    Full Text Available Se abordan los principios y categorías que sustentan el tratamiento educativo en la atención a las necesidades educativas especiales originadas por el fenómeno desamparo familiar, desde la concepción de familia, teniendo en cuenta que en los centros de asistencia social donde son atendidos los menores sin amparo familiar se debe cumplir con las funciones establecidas para la familia en nuestra sociedad. Se reflejan elementos que obligatoriamente deben tenerse en cuenta para favorecer el desarrollo de la esfera afectiva como las vivencias, actividad, educación, enfatizando en las características de esta esfera, base de la personalidad, unida a la cognitiva.

  1. Optimization of a bolometer detector for ITER based on Pt absorber on SiN membrane

    Energy Technology Data Exchange (ETDEWEB)

    Meister, H.; Eich, T.; Endstrasser, N.; Giannone, L.; Kannamueller, M.; Kling, A.; Koll, J.; Trautmann, T. [Max-Planck-Institut fuer Plasmaphysik, EURATOM Association, Boltzmannstr. 2, D-85748 Garching (Germany); Detemple, P.; Schmitt, S. [Institut fuer Mikrotechnik Mainz GmbH, Carl-Zeiss-Str. 18-20, D-55129 Mainz (Germany); Collaboration: ASDEX Upgrade Team

    2010-10-15

    Any plasma diagnostic in ITER must be able to operate at temperatures in excess of 200 deg. C and neutron loads corresponding to 0.1 dpa over its lifetime. To achieve this aim for the bolometer diagnostic, a miniaturized metal resistor bolometer detector based on Pt absorbers galvanically deposited on SiN membranes is being developed. The first two generations of detectors featured up to 4.5 {mu}m thick absorbers. Results from laboratory tests are presented characterizing the dependence of their calibration constants under thermal loads up to 450 deg. C. Several detectors have been tested in ASDEX Upgrade providing reliable data but also pointing out the need for further optimization. A laser trimming procedure has been implemented to reduce the mismatch in meander resistances below 1% for one detector and the thermal drifts from this mismatch.

  2. Recent results of μCF experiments at SIN [Swiss Institute For Nuclear Research

    International Nuclear Information System (INIS)

    Breunlich, W.H.; Cargnelli, M.; Bistirlich, J.

    1986-09-01

    Important topics concerning Muon Catalyzed Fusion were investigated in experiments at the Swiss Institute for Nuclear Research (SIN), including transient and steady state rates for the main dμt cycle as well as detailed information about the competing dμd and tμt fusion branches. The basic kinetic parameters were determined and striking features of the resonant dμt formation process were revealed (density effect, epithermal behavior). DT sticking was measured with independent techniques, i.e., detection of fusion neutrons as well as μHe x-rays after fusion. Fusion yields per muon of 113 +- 10 were observed at liquid conditions, yields exceeding 200 are anticipated for optimal conditions from our results. 43 refs., 8 figs., 3 tabs

  3. Optimization of a bolometer detector for ITER based on Pt absorber on SiN membranea)

    Science.gov (United States)

    Meister, H.; Eich, T.; Endstrasser, N.; Giannone, L.; Kannamüller, M.; Kling, A.; Koll, J.; Trautmann, T.; ASDEX Upgrade Team; Detemple, P.; Schmitt, S.

    2010-10-01

    Any plasma diagnostic in ITER must be able to operate at temperatures in excess of 200 °C and neutron loads corresponding to 0.1 dpa over its lifetime. To achieve this aim for the bolometer diagnostic, a miniaturized metal resistor bolometer detector based on Pt absorbers galvanically deposited on SiN membranes is being developed. The first two generations of detectors featured up to 4.5 μm thick absorbers. Results from laboratory tests are presented characterizing the dependence of their calibration constants under thermal loads up to 450 °C. Several detectors have been tested in ASDEX Upgrade providing reliable data but also pointing out the need for further optimization. A laser trimming procedure has been implemented to reduce the mismatch in meander resistances below 1% for one detector and the thermal drifts from this mismatch.

  4. residenciales de madres sin cónyuge en Ciudad Juárez

    Directory of Open Access Journals (Sweden)

    Claudia Zamorano Villarreal

    2006-01-01

    Full Text Available Se abordarán los itinerarios y las prácticas residenciales de madres sin cónyuge en Ciudad Juárez, ese punto de convergencia de inmigrantes nacionales y capitales internacionales y ahora, una de las más importantes ciudades maquiladoras del país. A partir de 51 historias de vida con trabajadoras de esta industria, se comparan los itinerarios residenciales de familias monoparentales con los de familias biparentales. Esta comparación permite ver las desventajas de las primeras para ingresar al mercado de la vivienda, que no se explican únicamente por factores de orden económico, sino también moral y práctico.

  5. Lithography-based fabrication of nanopore arrays in freestanding SiN and graphene membranes

    Science.gov (United States)

    Verschueren, Daniel V.; Yang, Wayne; Dekker, Cees

    2018-04-01

    We report a simple and scalable technique for the fabrication of nanopore arrays on freestanding SiN and graphene membranes based on electron-beam lithography and reactive ion etching. By controlling the dose of the single-shot electron-beam exposure, circular nanopores of any size down to 16 nm in diameter can be fabricated in both materials at high accuracy and precision. We demonstrate the sensing capabilities of these nanopores by translocating dsDNA through pores fabricated using this method, and find signal-to-noise characteristics on par with transmission-electron-microscope-drilled nanopores. This versatile lithography-based approach allows for the high-throughput manufacturing of nanopores and can in principle be used on any substrate, in particular membranes made out of transferable two-dimensional materials.

  6. COMUNICACIÓN, CONOCIMIENTO Y PODER SIN AGENDA SOBRE LA SEGURIDAD CIUDADANA

    Directory of Open Access Journals (Sweden)

    Manuel de Jesús Rocha Picón

    2014-07-01

    Full Text Available Este trabajo reflexiona analíticamente sobre la comunicación, el poder y el conocimiento sin agenda sobre la seguridad ciudadana. En la comunicación está surgiendo el “Paradigma de comunicación de seguridad”, con fuertes bases éticas, moral y ciudadana, como mecanismo de colaboración mutua y prioridad en las relaciones de comunicación. Las relaciones de poder se basan en el “Paradigma de la dialógica” promoviendo espacios de diálogo y discusión. En el conocimiento se crearían condiciones y estrategias apropiadas para promoverse, articulando programas tanto a nivel local, sectorial, institucional y universitario, para brindar un esarrollo de la seguridad ciudadana con una fuerte base científica.

  7. Adolfo Bioy casares y Mario Bellatin: sobre cartas sin cuerpo y acantilados

    Directory of Open Access Journals (Sweden)

    Karla Fernandes Cipreste

    2016-10-01

    Full Text Available Se propone una lectura de dos escritores hispanoamericanos – Adolfo Bioy Casares y Mario Bellatin – con el propósito de reflexionar sobre discursos de poder, incluido el ámbito de la Crítica Latinoamericana. Se entienden las experiencias de los personajes de sus obras, y también el ethos de ambos los autores, como una existência ética y estética que resiste a los intentos de categorizaciones. La propuesta se hace a la luz del concepto de Comunidad, del filósofo italiano Roberto Esposito, y de la discusión de Hugo Achugar sobre lo local y lo global en América Latina. Dos imágenes inspiran ese análisis: la carta sin cuerpo en Dormir al sol, de Casares; y el acantilado de Bellatin en Los fantasmas del masajista.

  8. Autoprotección del aluminio anodizado sin sellar expuesto a la atmósfera

    Directory of Open Access Journals (Sweden)

    Escudero, E.

    2005-04-01

    Full Text Available To confirm or refute the widely held idea that the sealing operation is vital to guarantee the good resistance of anodised aluminium to atmospheric corrosion, unsealed anodised specimens with three different film thicknesses were exposed in 9 atmospheres in Iberoamérica with salinity values of between 3.9 and 684 mg m sup>-2 day-1 of chlorides. Using a wide variety of techniques, from scanning and transmission electron microscopy to direct measurements by gravimetry, and including indirect measurements by electrochemical techniques as well as standard sealing quality control tests, the self-sealing capacity of unsealed anodic coatings during atmospheric exposure is demonstrated. Surprisingly, unlike other types of protective coatings, the quality of anodic films improves with ageing. Keywords

    Para confirmar o rebatir la idea, muy difundida, de que la operación de sellado es imprescindible para garantizar una buena resistencia del aluminio anodizado a la corrosión atmosférica, se expusieron muestras de anodizados sin sellar, de tres espesores diferentes, en 9 atmósferas de Iberoamérica, con salinidades comprendidas entre 3,9 y 684 mg m-2 d-1 de cloruros. Por las más variadas técnicas, desde la microscopía electrónica de barrido o transmisión a la medida directa por gravimetría, pasando por los ensayos normalizados de control de calidad del sellado y la medida indirecta por técnicas electroquímicas, se demuestra la capacidad de autosellado, durante la exposición a la atmósfera, de los recubrimientos anódicos sin sellar. Sorprendentemente, a diferencia de lo que ocurre en recubrimientos protectores de otra naturaleza, la calidad de los anodizados mejora con el envejecimiento.

  9. Composition, structure and properties of SiN x films fabricated by pulsed reactive closed-field unbalanced magnetron sputtering

    International Nuclear Information System (INIS)

    Yao, Zh.Q.; Yang, P.; Huang, N.; Sun, H.; Wan, G.J.; Leng, Y.X.; Chen, J.Y.

    2005-01-01

    Silicon nitride (SiN x ) thin films are of special interest in both scientific research and industrial applications due to their remarkable properties such as high thermal stability, chemical inertness, high hardness and good dielectric properties. In this work, SiN x films were fabricated by pulsed reactive closed-field unbalanced magnetron sputtering of high purity single crystal silicon targets in an Ar-N 2 mixture. The effect of N 2 partial pressure on the film composition, chemical bonding configurations, surface morphology, surface free energy, optical and mechanical properties were investigated. We showed that with increased N 2 partial pressure, the N to Si ratio (N/Si) in the film increased and N atoms are preferentially incorporated in the NSi 3 stoichiometric configuration. It leads the Si-N network a tendency to chemical order. Films deposited at a high N 2 fraction were consistently N-rich. The film surface transformed from a loose granular structure with microporosity to a homogeneous, continuous, smooth and dense structure. A progressive densification of the film microstructure occurs as the N 2 fraction is increased. The reduced surface roughness and the increased N incorporation in the film give rise to the increased contact angle with double-distilled water from 24 o to 49.6 o . To some extent, the SiN x films deposited by pulsed magnetron sputtering are hydrophilic in nature. The as-deposited SiN x films exhibit good optical transparency in the visible region and the optical band gap E opt can be varied from 1.68 eV for a-Si to 3.62 eV for SiN x films, depending on the synthesis parameters. With the increase of the N/Si atomic ratio, wear resistance of the SiN x films was improved, a consequence of increased hardness and elastic modulus. The SiN x films have lower friction coefficient and better wear resistance than 316L stainless steel under dry sliding friction, where the SiN x films experienced only fatigue wear

  10. A Novel Robust H∞ Filter Based on Krein Space Theory in the SINS/CNS Attitude Reference System

    Directory of Open Access Journals (Sweden)

    Fei Yu

    2016-03-01

    Full Text Available Owing to their numerous merits, such as compact, autonomous and independence, the strapdown inertial navigation system (SINS and celestial navigation system (CNS can be used in marine applications. What is more, due to the complementary navigation information obtained from two different kinds of sensors, the accuracy of the SINS/CNS integrated navigation system can be enhanced availably. Thus, the SINS/CNS system is widely used in the marine navigation field. However, the CNS is easily interfered with by the surroundings, which will lead to the output being discontinuous. Thus, the uncertainty problem caused by the lost measurement will reduce the system accuracy. In this paper, a robust H∞ filter based on the Krein space theory is proposed. The Krein space theory is introduced firstly, and then, the linear state and observation models of the SINS/CNS integrated navigation system are established reasonably. By taking the uncertainty problem into account, in this paper, a new robust H∞ filter is proposed to improve the robustness of the integrated system. At last, this new robust filter based on the Krein space theory is estimated by numerical simulations and actual experiments. Additionally, the simulation and experiment results and analysis show that the attitude errors can be reduced by utilizing the proposed robust filter effectively when the measurements are missing discontinuous. Compared to the traditional Kalman filter (KF method, the accuracy of the SINS/CNS integrated system is improved, verifying the robustness and the availability of the proposed robust H∞ filter.

  11. [Control levels of Sin3 histone deacetylase for spontaneous and UV-induced mutagenesis in yeasts Saccharomyces cerevisiae].

    Science.gov (United States)

    Lebovka, I Iu; Kozhina, T N; Fedorova, I V; Peshekhonov, V T; Evstiukhina, T A; Chernenkov, A Iu; Korolev, V G

    2014-01-01

    SIN3 gene product operates as a repressor for a huge amount of genes in Saccharomyces cerevisiae. Sin3 protein with a mass of about 175 kDa is a member of the RPD3 protein complex with an assessed mass of greater than 2 million Da. It was previously shownthat RPD3 gene mutations influence recombination and repair processes in S. cerevisiae yeasts. We studied the impacts of the sin3 mutation on UV-light sensitivity and UV-induced mutagenesis in budding yeast cells. The deletion ofthe SIN3 gene causes weak UV-sensitivity of mutant budding cells as compared to the wild-type strain. These results show that the sin3 mutation decreases both spontaneous and UV-induced levels of levels. This fact is hypothetically related to themalfunction of ribonucleotide reductase activity regulation, which leads to a decrease in the dNTP pool and the inaccurate error-prone damage bypass postreplication repair pathway, which in turn provokes a reduction in the incidence of mutations.

  12. Búsqueda de Colocaciones en la Web para Sinónimos de Wordnet Búsqueda de Colocaciones en la Web para Sinónimos de Wordnet

    Directory of Open Access Journals (Sweden)

    M. Montes -y-Gómez

    2012-02-01

    Full Text Available La Web es sin lugar a dudas el repositorio de información más grande jamás construido por el ser humano. Con más de cuatro mil millones de páginas indexadas por los motores de búsqueda públicos, la Web representa el mayor y más amplio corpus textual disponible en la actualidad. Por su valor lingüístico, dado que contiene información en más de 1 500 lenguajes, este corpus está siendo usado con gran éxito en muchas tareas de procesamientodel lenguaje natural. En particular, varios métodos de minería de datos se han aplicado para extraer de la Web algunos tipos de patrones lingüísticos útiles para tareas como la traducción automática y búsqueda de respuestas. En este artículo presentamos un método que permite encontrar combinaciones de palabras significativas a los diferentes sentidos atribuibles a una palabra polisémica. Los experimentos realizados, aunque preliminares, muestran el gran potencial del método propuesto para encontrar estas colocaciones por sentido usando la Web como corpus, así como la viabilidad de la incorporación de dichas colocaciones en sistemas de desambiguación del sentido de las palabras, que pueden a su vez ser usados en sistemas de traducción automática y recuperación de información.There is no doubt that the Web is the biggest information repository ever before constructed by human beings. With more than four billion pages index-linked by the public search engines, the Web represents the biggest and the widest textual corpus available in our days. Because his high linguistic value, because contains information in more than 1500 different languages, this corpus is being used with great success in many tasks related to the natural language process. In particular, several methods of data mining have been applied to extract from the Web some types of linguistic patterns which are useful for a diversity of tasks, such as automatic translations and answer search systems. In this work we presenta

  13. $\\sin(2\\beta)$ with $B^0 \\rightarrow\\!J/\\!\\psi K_\\text{S}$ at the LHCb experiment

    CERN Multimedia

    Niet, Ramon

    2015-01-01

    The poster presents the recent measurement of $\\sin(2\\beta)$ using $B^0$ decays to the $J/\\!\\psi K_\\text{S}$ final state. The measurement is based on a dataset corresponding to an integrated luminosity of 3.0$\\,\\text{fb}^{-1}$ collected with the LHCb experiment in proton-proton collisions at center-of-mass energies of 7 and 8 TeV. To control penguin pollutions in the determination of $\\sin(2\\beta)$, $B_s^0$ decays to the same final state can be analysed. The results of the corresponding analysis are presented as well.

  14. Cele șapte păcate ale greenwashing-ului [The seven sins of greenwashing

    Directory of Open Access Journals (Sweden)

    Drăgoi M

    2016-12-01

    Full Text Available This editorial tackles a problem the Romanian forestry journals have never dealt with: the greenwashing phenomenon. After a brief excursion into the communication clichés consciously or unconsciously delivered by the media to the public, we have scrutinized the seven sins of greenwashing, found into the forestry sector or promoted by the public authority responsible for environmental protection. The first sin we have found refers to the hidden trade-offs and the best example in this respect is the stumpage price. Being too high, neither the forest administrator/owner nor the contractor pays attention to the quality of the harvesting process, compromising the natural regeneration, destroying the upper soil and triggering erosion processes. Lack of evidence about the misbehavior of forest inspectors or unsubstantiated allegation when it comes to the ones responsible with forest regime supervision is the second sin, followed by the sin of vagueness. The best example of vague statement is the concept of favorable conservation status, barely defined for species but hard to define for large habitats. The sin of worship false labels goes along with the forest management planning system still stuck to the sustained yield principle even for very small forest ownerships, unable to produce steady annual yields simply because a regular age structure cannot be ever reached. The sin of irrelevance was exemplified by the paper waste that follows each public awareness campaign based on colorful flyers, personalized plastic ballpoint pens, folders and so on. Compared to the environmental cost of having this paper recycled the social benefit of having used this paper-based material fades out. The sin of lesser of two evils pops up whenever the public authority fails to enforce the best available technology, which sometime comes about with a higher social cost or less fringe benefits for all people working in forestry. After the collapse of the communist regime

  15. Una contribución al análisis de problemas de flujo compresible sin utilizacion de viscocidad artificial

    OpenAIRE

    Quintana, F.

    1994-01-01

    En este trabajo se presentan unas técnicas desarrolladas con el objeto de obtener un algoritmo para la solución de problemas de flujo compresible sin la aplicación de términos de viscosidad artificial. Esto es motivado por el hecho de que si bien la calidad de la solución obtenida mediante procedimientos conocidos es muy buena -en particular los choques y las capas límite son capturados de manera muy precisa y sin oscilaciones-, en muchas ocasiones es preciso recurrir a la pericia del usuario...

  16. Diferencias comportamentales en gallinas ponedoras con y sin el "Método Llovera" durante el período primaveral.

    OpenAIRE

    Mentzel, Rubén

    2009-01-01

    Recibido: Dic.2008 | Aceptado: Abr.2009 En trabajos anteriores se demostraron las ventajas del control de moscas en galpones de gallinas ponedoras, aplicando el “Método Llovera”. El mismo consiste en colocar gallinas de descarte en el piso, sin alimentación propia, en una cantidad correspondiente al 10% de los animales del galpón.1 De esta forma se logra disminuir la cantidad de moscas, y aumentar la producción de huevos mejorando la calidad y la rentabilidad. Un ambiente sin moscas es mu...

  17. Influencia de los trastornos mentales y de la personalidad en el abandono de procesos en personas sin hogar

    OpenAIRE

    Salavera, Carlos

    2014-01-01

    Las personas sin hogar protagonizan un alto índice de abandonos en los procesos terapéuticos que establecen. El motivo de abandono no siempre es conocido, en esta investigación se aborda si viene mediado por los trastornos mentales o son los trastornos de personalidad los que llevan un mayor peso. Los resultados muestran a las personas sin hogar con deterioro cognitivo leve y trastornos de personalidad del grupo de problemas interpersonales y ambivalentes como los principales candidatos al ab...

  18. Degradación térmica del γ‐orizanol en pastas sin gluten

    OpenAIRE

    Soto Jover, Sonia; Boluda Aguilar, María; López Gómez, Antonio

    2014-01-01

    La harina de arroz es el cereal más adecuado para elaborar productos sin gluten, debido a sus propiedades nutricionales y antioxidantes, y a su alto contenido en γ–orizanol. Además también posee propiedades hipoalergénicas y un color y aroma suave. Dado el gran interés del γ–orizanol desde el punto de vista nutraceútico, y a que existen pocos estudios sobre el efecto de la cocción de alimentos sin gluten (elaborados con harina de arroz) sobre el contenido de γ‐orizanol, en este trabajo se est...

  19. Sistemas de control de gestion, analisis para organizaciones sin fines de lucro

    Directory of Open Access Journals (Sweden)

    Juan Ricardo Saldías Cerda

    2006-07-01

    Full Text Available En la presente investigación se revisarán distintos modelos de control de gestión y como estos han evolucionado desde los basados exclusivamente en la contabilidad, hasta hoy en día, en que la incorporación de conceptos como capital humano y Stakeholder son considerados como elementos claves. Modelos que también han sido considerado por las instituciones sin fines de lucro, como son las organizaciones  públicas en su implantación de la estrategia. Junto a la revisión de los antecedentes bibliográficos, se procedió a realizar algunas comparaciones de modelos encontrados, en  particular se utilizó el Cuadro de Mando Integral (CMI como referencia, en sus distintos estados evolutivos, el cual ha incorporado cada vez con mayor énfasis el concepto de capital humano en su enfoque. Además, se consideró el concepto de Stakeholder, planteado por algunos autores como una variable imprescindible en el planteamiento estratégico y posterior desarrollo del modelo de gestión. Lo anterior permitió definir el marco referencial, para plantear un modelo que pudiese ser aplicado en organizaciones sin fines de lucro, como lo es un hospital público. En donde se deben tener presente las diferentes restricciones estructurales y culturales que afectan o interfieren en la aplicación de cualquier modelo o estrategia, representados y descritos en los Satkeholder. Next to the revision of the bibliographical antecedents, proceeded to carry out some comparisons of models found, particularly the Balance Scorecard was utilized (BSC as reference, in its different evolutionary states, which has incorporated each time with greater emphasis the concept of human capital in its focus. Besides, the concept was considered of Stakeholder, presented by some authors as an indispensable variable in the approach strategic and subsequent development of the model of management. The previous thing permitted to define the framework referential, to present a model that could

  20. Differential lymphocyte and antibody responses in deer mice infected with Sin Nombre hantavirus or Andes hantavirus.

    Science.gov (United States)

    Schountz, Tony; Quackenbush, Sandra; Rovnak, Joel; Haddock, Elaine; Black, William C; Feldmann, Heinz; Prescott, Joseph

    2014-08-01

    Hantavirus cardiopulmonary syndrome (HCPS) is a rodent-borne disease with a high case-fatality rate that is caused by several New World hantaviruses. Each pathogenic hantavirus is naturally hosted by a principal rodent species without conspicuous disease and infection is persistent, perhaps for life. Deer mice (Peromyscus maniculatus) are the natural reservoirs of Sin Nombre virus (SNV), the etiologic agent of most HCPS cases in North America. Deer mice remain infected despite a helper T cell response that leads to high-titer neutralizing antibodies. Deer mice are also susceptible to Andes hantavirus (ANDV), which causes most HCPS cases in South America; however, deer mice clear ANDV. We infected deer mice with SNV or ANDV to identify differences in host responses that might account for this differential outcome. SNV RNA levels were higher in the lungs but not different in the heart, spleen, or kidneys. Most ANDV-infected deer mice had seroconverted 14 days after inoculation, but none of the SNV-infected deer mice had. Examination of lymph node cell antigen recall responses identified elevated immune gene expression in deer mice infected with ANDV and suggested maturation toward a Th2 or T follicular helper phenotype in some ANDV-infected deer mice, including activation of the interleukin 4 (IL-4) pathway in T cells and B cells. These data suggest that the rate of maturation of the immune response is substantially higher and of greater magnitude during ANDV infection, and these differences may account for clearance of ANDV and persistence of SNV. Hantaviruses persistently infect their reservoir rodent hosts without pathology. It is unknown how these viruses evade sterilizing immune responses in the reservoirs. We have determined that infection of the deer mouse with its homologous hantavirus, Sin Nombre virus, results in low levels of immune gene expression in antigen-stimulated lymph node cells and a poor antibody response. However, infection of deer mice with a

  1. Bocio multinodular gigante deformante. Presentación de un caso sin síntomas obstructivos

    Directory of Open Access Journals (Sweden)

    Paul Bogucki

    2014-04-01

    Full Text Available Se presenta el caso de un paciente masculino de 50 años, con una tumoración en la parte anterior de cuello de 25 años de evolución, sin síntomas de compresión. Al examen físico se aprecia una glándula tiroides de gran tamaño que deforma el cuello, de superficie lisa y nodular, de aproximadamente 16x12cm. Los estudios de imágenes y de laboratorio confirmaron el diagnóstico. Se practicó una tiroidectomía total, obteniéndose una glándula de 17x12cm. Se identificaron y preservaron ambos nervios laríngeos recurrentes y las glándulas paratiroides. No hubo complicaciones postoperatorias y el resultado estético fue satisfactorio. En conclusión el bocio es una patología común en las zonas con insuficiente aporte de Yodo, donde tiene una incidencia aproximada de 11%. Las estadísticas obtenidas en nuestro hospital se corresponden con lo publicado en la literatura internacional. La variedad gigante es infrecuente, constituyendo una causa de síntomas compresivos y disconformidad estética, por lo que la cirugía es la indicación terapéutica. Abstract Giant multinodular goiter. A case report with no obstructive symptoms In this report we show a 50 years male patient with a tumor in the anterior part of neck of 25 years of evolution, without symptoms of compression. Physical examination shows a large thyroid gland, which deforms the neck, smooth and nodular, painless to palpation, approximately 16x12cm. Imaging studies and laboratory-confirmed diagnosis of multinodular goiter. A total thyroidectomy was performed, with a gland 17x12cm. Were identified and preserved both recurrent laryngeal nerves and parathyroid glands. There were no postoperative complications and the aesthetic result was satisfactory. In conclusion the goiter is a condition common in areas with insufficient supply of iodine, which has an incidence of approximately 11%. The statistics obtained in our hospital are as published in the international literature to endemic

  2. HISTOPATOLOGIA DE LA INFECCIÓN EXPERIMENTAL DE OVEJAS SIN LANA Ovis aries POR Neospora caninum

    Directory of Open Access Journals (Sweden)

    Teresa Oviedo

    2003-01-01

    Full Text Available Ovejas sin lana en diferentes estados reproductivos fueron inoculadas por vía intravenosa con taquizoítos deN. caninum muestra «NC-beef» con el fin de estudiar la patofisiología de la enfermedad en estos animales yverificar la posibilidad de ser usados como modelo experimental de neosporosis bovina. Se utilizaron cincoovejas gestantes (una con 15 días, dos con 30 días, dos con 90 días, tres no gestantes y dos con 10 díasposparto. Los animales eran serologicamente negativos para N.caninum y T. gondii. Dos ovejas gestantes, noinoculadas, fueron utilizadas como control negativo. Los corderos necropsiados, nacidos de ovejas inoculadasantes o durante la gestación presentaron alteraciones histopatológicas en diferentes tejidos, siendo las masseveras observadas en el sistema nervioso central, caracterizadas por la presencia de formas quísticas delparásito asociadas con infiltrado inflamatorio predominantemente mononuclear, áreas de necrosis y en algunoscasos presencia de calcificación. Los corderos nacidos de ovejas inoculadas 10 días después del parto nopresentaron signos clínicos de la enfermedad ni anticuerpos contra o parásito y a la necropsia no presentaronlesiones en ninguno de los tejidos analizados. Un cordero nacido de oveja no inoculada no presentó alteracionesmicroscópicas en ninguno de los tejidos analizados

  3. Smokers’ Strategic Responses to Sin Taxes: Evidence from Panel Data in Thailand

    Science.gov (United States)

    White, Justin S.; Ross, Hana

    2014-01-01

    In addition to quitting and cutting consumption, smokers faced with higher cigarette prices may compensate in several ways that mute the health impact of cigarette taxes. This study examines three price avoidance strategies among adult male smokers in Thailand: trading down to a lower-priced brand, buying individual sticks of cigarettes instead of packs, and substituting roll-your-own (RYO) tobacco for factory-manufactured cigarettes. Using two panels of microlevel data from the International Tobacco Control Southeast Asia Study, collected in 2005 and 2006, we estimate the effects of a substantial excise tax increase implemented throughout Thailand in December 2005. We present estimates of the marginal effects and price elasticities for each of five consumer behaviors. We find that, controlling for baseline smoking characteristics, socio-demographics, and policy variables, quitting is highly sensitive to changes in cigarette prices, but so are brand choice, stick-buying, and use of RYO tobacco. Neglecting such strategic responses leads to over-estimates of a sin tax’s health impact, and neglecting product substitution distorts estimates of the price elasticity of cigarette demand. We discuss the implications for consumer welfare and several policies that mitigate the adverse impact of consumer responses. PMID:24677731

  4. Smokers' strategic responses to sin taxes: evidence from panel data in Thailand.

    Science.gov (United States)

    White, Justin S; Ross, Hana

    2015-02-01

    In addition to quitting and cutting consumption, smokers faced with higher cigarette prices may compensate in several ways that mute the health impact of cigarette taxes. This study examines three price avoidance strategies among adult male smokers in Thailand: trading down to a lower-priced brand, buying individual sticks of cigarettes instead of packs, and substituting roll-your-own tobacco for factory-manufactured cigarettes. Using two panels of microlevel data from the International Tobacco Control Southeast Asia Study, collected in 2005 and 2006, we estimate the effects of a substantial excise tax increase implemented throughout Thailand in December 2005. We present estimates of the marginal effects and price elasticities for each of five consumer behaviors. We find that, controlling for baseline smoking characteristics, sociodemographics, and policy variables, quitting is highly sensitive to changes in cigarette prices, but so are brand choice, stick-buying, and use of roll-your-own tobacco. Neglecting such strategic responses leads to overestimates of a sin tax's health impact, and neglecting product substitution distorts estimates of the price elasticity of cigarette demand. We discuss the implications for consumer welfare and several policies that mitigate the adverse impact of consumer responses. Copyright © 2013 John Wiley & Sons, Ltd.

  5. Coarse Alignment Technology on Moving base for SINS Based on the Improved Quaternion Filter Algorithm.

    Science.gov (United States)

    Zhang, Tao; Zhu, Yongyun; Zhou, Feng; Yan, Yaxiong; Tong, Jinwu

    2017-06-17

    Initial alignment of the strapdown inertial navigation system (SINS) is intended to determine the initial attitude matrix in a short time with certain accuracy. The alignment accuracy of the quaternion filter algorithm is remarkable, but the convergence rate is slow. To solve this problem, this paper proposes an improved quaternion filter algorithm for faster initial alignment based on the error model of the quaternion filter algorithm. The improved quaternion filter algorithm constructs the K matrix based on the principle of optimal quaternion algorithm, and rebuilds the measurement model by containing acceleration and velocity errors to make the convergence rate faster. A doppler velocity log (DVL) provides the reference velocity for the improved quaternion filter alignment algorithm. In order to demonstrate the performance of the improved quaternion filter algorithm in the field, a turntable experiment and a vehicle test are carried out. The results of the experiments show that the convergence rate of the proposed improved quaternion filter is faster than that of the tradition quaternion filter algorithm. In addition, the improved quaternion filter algorithm also demonstrates advantages in terms of correctness, effectiveness, and practicability.

  6. Interacciones sin nombre. Un caso emblemático: Ne me quitte pas (Cirque du Soleil

    Directory of Open Access Journals (Sweden)

    Óscar Quezada-Macchiavello

    2014-02-01

    Full Text Available El presente artículo esboza una teoría tensiva, figural, de la interacción, que se opone y complementa con la teoría narrativa y fi gurativa propuesta por Eric Landowski. Esta última propone una taxonomía de las interacciones dispuesta en el cuadrado semiótico; aquella, mientras tanto, respetando dicha taxonomía, la dispone en intervalo(s sobre los que se deslizan cursos vectoriales. Estos últimos dan cuenta de cuatro zonas de tensión: desprogramación, reprogramación, desajuste, reajuste. Esa irrupción de la gradualidad permite imaginar una gama de «interacciones sin nombre». La mencionada propuesta teórica se pone a prueba en el análisis de las cómicas peripecias de una parodia de la célebre canción de Jacques Brel, Ne me quitt e pas, puesta en escena por el Cirque du Soleil’s Varekai.

  7. Heavy metals in Sinú river, department of Córdoba, Colombia, South America

    Directory of Open Access Journals (Sweden)

    John Jairo Feria

    2010-01-01

    Full Text Available Se evaluaron las concentraciones de Al, Fe, Mn, Zn, Cu, Ni, Cr, Hg, Pb y Cd en sedimentos superficiales del río Sinú. Las muestras se recolectaron en 10 sitios de muestreo aguas abajo del embalse de Urrá I, considerándose dos períodos de muestreo, uno en época de lluvia y otro en época seca. Las concentraciones de los metales se determinaron por espectrofotometría de absorción atómica o por voltametría y se normalizaron con respecto a las concentraciones del aluminio, por ser un metal conservativo. Se observó una fuerte correlación entre las concentraciones de Cu, Ni, Cr y Zn para ambos períodos muestreados, sugiriendo un origen común. Adicionalmente, el factor de enriquecimiento indicó para todos los elementos evaluados, a excepción del Fe, concentraciones enriquecidas de metales pesados en los sedimentos. En los sitios que reciben el impacto de los suelos inundados, existe una mayor concentración de metales en los sedimentos, comparada con otras zonas de la cuenca, lo cual se asocia con la reducción de sulfatos y la formación de sulfuros y la subsecuente liberación y disponibilidad de metales pesados.

  8. Optimization Algorithm for Kalman Filter Exploiting the Numerical Characteristics of SINS/GPS Integrated Navigation Systems.

    Science.gov (United States)

    Hu, Shaoxing; Xu, Shike; Wang, Duhu; Zhang, Aiwu

    2015-11-11

    Aiming at addressing the problem of high computational cost of the traditional Kalman filter in SINS/GPS, a practical optimization algorithm with offline-derivation and parallel processing methods based on the numerical characteristics of the system is presented in this paper. The algorithm exploits the sparseness and/or symmetry of matrices to simplify the computational procedure. Thus plenty of invalid operations can be avoided by offline derivation using a block matrix technique. For enhanced efficiency, a new parallel computational mechanism is established by subdividing and restructuring calculation processes after analyzing the extracted "useful" data. As a result, the algorithm saves about 90% of the CPU processing time and 66% of the memory usage needed in a classical Kalman filter. Meanwhile, the method as a numerical approach needs no precise-loss transformation/approximation of system modules and the accuracy suffers little in comparison with the filter before computational optimization. Furthermore, since no complicated matrix theories are needed, the algorithm can be easily transplanted into other modified filters as a secondary optimization method to achieve further efficiency.

  9. The Seven (Or More) Deadly (Or Not So Deadly) Sins of Radiation Protection

    International Nuclear Information System (INIS)

    Strom, Daniel J.; Stansbury, Paul S.

    1999-01-01

    This editorial considers the errors that can occur in the routine practice of radiation protection in the workplace. This work provides a tool and an incentive for radiation protection professionals to mentally examine their radiation protection responsibilities to identify actions they may take to improve their part of the practice of radiation protection for the benefit of humankind. We introduce a rating tool that is patterned after the IAEA International Nuclear Event Scale.?Sins? discussed include ignorance of the radiological situation, failure to integrate safety management, disabling safety interlocks, warning devices, access controls, omission of''reasonable'' from the policy of''as low as reasonably achievable'' (ALARA), extrapolation of risk beyond reason, using radiation exposure as an excuse for terminating an unwanted pregnancy, escalation of safety requirements beyond reason, failure to average a concentration standard, not responding to concerns (of workers, public, patient s, etc.), over-training, and substitution of prescriptive procedures for judgment. Readers are encouraged to look at their radiation protection activities and judge which ones do not make sense from the viewpoint of protecting people against radiation. It is likely that readers will find more than one radiation protection activity that bears scrutiny

  10. Existir sin ser visto. Aproximaciones a una teoría del sujeto espectador

    Directory of Open Access Journals (Sweden)

    Luis PUELLES ROMERO

    2009-08-01

    Full Text Available RESUMEN: Desde la constatación de un sorprendente desequilibrio entre la evidente participación del espectador en el hecho artístico y la escasa dedicación que sin embargo ha recibido por parte de la Estética y la Historia del arte, estas páginas indagan en las razones de esta insuficiencia de la teoría, además de aportar algunos puntos de vista de utilidad para la elaboración de una estética de los espectadores que concrete y complete la Estética de la Recepción de la Escuela de Constanza.ABSTRACT: This article stems from the obvious lack of balance between the active participation of the spectator in the artistic event, and the lack of attention he has received in Aesthetics and Art History. It explores the reasons for this insufficiency in art theory, as it puts forward an outline for an aesthetics of the spectator that can be added to the reception theory of the Constance School.

  11. El dilema de los recursos naturales comunes "sin doliente(s"

    Directory of Open Access Journals (Sweden)

    Reyes Parra Leidy Marcela

    2011-11-01

    Full Text Available Desde la antigüedad, personas como Aristóteles y Tucídides plantearon una teoría básica que evidenció el comportamiento que las personas tienen con respecto al uso continuo de algún recurso natural común. Dejaron entrever el conflicto, normalmente económico, que se genera por la intervención de intereses individuales sobre los bienes públicos. La tragedia de los comunes (término popularizado por Garrett Hardin en 1968 explica cómo el acceso sin restricciones a un recurso "comunal" finito conduce a la sobreexplotación y al agotamiento de dicho recurso por el aumento desmedido en su demanda. Esto ocurre porque el grupo o los individuos que aprovechan los recursos no cargan directamente con los costos de su explotación. Entonces frente a la premisa de que el recurso es de todos y para todos, pero en última instancia, no pertenece a nadie, cabe preguntarse qué prima: ¿Un interés individual sobre un colectivo? O tal vez, ¿es una cuestión de enfoque etológico?

  12. Determination of sin2 θ {w/eff} using jet charge measurements in hadronic Z decays

    Science.gov (United States)

    Buskulic, D.; de Bonis, I.; Decamp, D.; Ghez, P.; Goy, C.; Lees, J. P.; Lucotte, A.; Minard, M. N.; Odier, P.; Pietrzyk, B.; Chmeissani, M.; Crespo, J. M.; Delfino, M.; Efthymiopoulos, I.; Fernandez, E.; Fernandez-Bosman, M.; Garrido, Ll.; Juste, A.; Martinez, M.; Orteu, S.; Pacheco, A.; Padilla, C.; Pascual, A.; Perlas, J. A.; Riu, I.; Sanchez, F.; Teubert, F.; Colaleo, A.; Creanza, D.; de Palma, M.; Gelao, G.; Girone, M.; Iaselli, G.; Maggi, G.; Maggi, M.; Marinelli, N.; Nuzzo, S.; Ranieri, A.; Raso, G.; Ruggieri, F.; Selvaggi, G.; Silvestris, L.; Tempesta, P.; Zito, G.; Huang, X.; Lin, J.; Ouyang, Q.; Wang, T.; Xie, Y.; Xu, R.; Xue, S.; Zhang, J.; Zhang, L.; Zhao, W.; Alemany, R.; Bazarko, A. O.; Bonvicini, G.; Cattaneo, M.; Comas, P.; Coyle, P.; Drevermann, H.; Forty, R. W.; Frank, M.; Hagelberg, R.; Harvey, J.; Janot, P.; Jost, B.; Kneringer, E.; Knobloch, J.; Lehraus, I.; Martin, E. B.; Mato, P.; Minten, A.; Miquel, R.; Mir, Ll. M.; Moneta, L.; Oest, T.; Palla, F.; Pater, J. R.; Pusztaszeri, J. F.; Ranjard, F.; Rensing, P.; Rolandi, L.; Schlatter, D.; Schmelling, M.; Schneider, O.; Tejessy, W.; Tomalin, I. R.; Venturi, A.; Wachsmuth, H.; Wagner, A.; Wildish, T.; Ajaltouni, Z.; Barrès, A.; Boyer, C.; Falvard, A.; Gay, P.; Guicheney, C.; Henrard, P.; Jousset, J.; Michel, B.; Monteil, S.; Montret, J.-C.; Pallin, D.; Perret, P.; Podlyski, F.; Proriol, J.; Rossignol, J. M.; Fearnley, T.; Hansen, J. B.; Hansen, J. D.; Hansen, J. R.; Hansen, P. H.; Nilsson, B. S.; Wäänänen, A.; Kyriakis, A.; Markou, C.; Simopoulou, E.; Siotis, I.; Vayaki, A.; Zachariadou, K.; Blondel, A.; Bonneaud, G.; Brient, J. C.; Bourdon, P.; Rougé, A.; Rumpf, M.; Valassi, A.; Verderi, M.; Videau, H.; Candlin, D. J.; Parsons, M. I.; Focardi, E.; Parrini, G.; Corden, M.; Georgiopoulos, C.; Jaffe, D. E.; Antonelli, A.; Bencivenni, G.; Bologna, G.; Bossi, F.; Campana, P.; Capon, G.; Casper, D.; Chiarella, V.; Felici, G.; Laurelli, P.; Mannocchi, G.; Murtas, F.; Murtas, G. P.; Passalacqua, L.; Pepe-Altarelli, M.; Curtis, L.; Dorris, S. J.; Halley, A. W.; Knowles, I. G.; Lynch, J. G.; O'Shea, V.; Raine, C.; Reeves, P.; Scarr, J. M.; Smith, K.; Ten Have, I.; Thompson, A. S.; Thomson, F.; Thorn, S.; Turnbull, R. M.; Becker, U.; Geweniger, C.; Graefe, G.; Hanke, P.; Hansper, G.; Hepp, V.; Kluge, E. E.; Putzer, A.; Rensch, B.; Schmidt, M.; Sommer, J.; Stenzel, H.; Tittel, K.; Werner, S.; Wunsch, M.; Abbaneo, D.; Beuselinck, R.; Binnie, D. M.; Cameron, W.; Dornan, P. J.; Moutoussi, A.; Nash, J.; Sedgbeer, J. K.; Stacey, A. M.; Williams, M. D.; Dissertori, G.; Girtler, P.; Kuhn, D.; Rudolph, G.; Bowdery, C. K.; Colrain, P.; Crawford, G.; Finch, A. J.; Foster, F.; Hughes, G.; Sloan, T.; Whelan, E. P.; Williams, M. I.; Galla, A.; Greene, A. M.; Kleinknecht, K.; Quast, G.; Renk, B.; Rohne, E.; Sander, H. G.; van Gemmeren, P.; Zeitnitz, C.; Aubert, J. J.; Bencheikh, A. M.; Benchouk, C.; Bonissent, A.; Bujosa, G.; Calvet, D.; Carr, J.; Diaconu, C.; Etienne, F.; Konstantinidis, N.; Payre, P.; Rousseau, D.; Talby, M.; Sadouki, A.; Thulasidas, M.; Trabelsi, K.; Abt, I.; Assmann, R.; Bauer, C.; Blum, W.; Dietl, H.; Dydak, F.; Ganis, G.; Gotzhein, C.; Jakobs, K.; Kroha, H.; Lütjens, G.; Lutz, G.; Männer, W.; Moser, H. G.; Richter, R.; Rosado-Schlosser, A.; Schael, S.; Settles, R.; Seywerd, H.; St. Denis, R.; Wiedenmann, W.; Wolf, G.; Boucrot, J.; Callot, O.; Cordier, A.; Davier, M.; Duflot, L.; Grivaz, J. F.; Heusse, Ph.; Jacquet, M.; Kim, D. W.; Le Diberder, F.; Lefrançois, J.; Lutz, A. M.; Nikolic, I.; Park, H. J.; Park, I. C.; Schune, M. H.; Simion, S.; Veillet, J. J.; Videau, I.; Azzurri, P.; Bagliesi, G.; Batignani, G.; Bettarini, S.; Bozzi, C.; Calderini, G.; Carpinelli, M.; Ciocci, M. A.; Ciulli, V.; Dell'Orso, R.; Fantechi, R.; Ferrante, I.; Foà, L.; Forti, F.; Giassi, A.; Giorgi, M. A.; Gregorio, A.; Ligabue, F.; Lusiani, A.; Marrocchesi, P. S.; Messineo, A.; Rizzo, G.; Sanguinetti, G.; Sciabà, A.; Spagnolo, P.; Steinberger, J.; Tenchini, R.; Tonelli, G.; Vannini, C.; Verdini, P. G.; Walsh, J.; Betteridge, A. P.; Blair, G. A.; Bryant, L. M.; Cerutti, F.; Chambers, J. T.; Gao, Y.; Green, M. G.; Medcalf, T.; Perrodo, P.; Strong, J. A.; von Wimmersperg-Toeller, J. H.; Botterill, D. R.; Clifft, R. W.; Edgecock, T. R.; Haywood, S.; Maley, P.; Norton, P. R.; Thompson, J. C.; Wright, A. E.; Bloch-Devaux, B.; Colas, P.; Emery, S.; Kozanecki, W.; Lançon, E.; Lemaire, M. C.; Locci, E.; Marx, B.; Perez, P.; Rander, J.; Renardy, J. F.; Roussarie, A.; Schuller, J. P.; Schwindling, J.; Trabelsi, A.; Vallage, B.; Black, S. N.; Dann, J. H.; Johnson, R. P.; Kim, H. Y.; Litke, A. M.; McNeil, M. A.; Taylor, G.; Booth, C. N.; Boswell, R.; Brew, C. A. J.; Cartwright, S.; Combley, F.; Koksal, A.; Letho, M.; Newton, W. M.; Reeve, J.; Thompson, L. F.; Böhrer, A.; Brandt, S.; Büscher, V.; Cowan, G.; Grupen, C.; Lutters, G.; Minguet-Rodriguez, J.; Rivera, F.; Saraiva, P.; Smolik, L.; Stephan, F.; Aleppo, M.; Apollonio, M.; Bosisio, L.; Della Marina, R.; Giannini, G.; Gobbo, B.; Musolino, G.; Ragusa, F.; Rothberg, J.; Wasserbaech, S.; Armstrong, S. R.; Bellantoni, L.; Elmer, P.; Feng, Z.; Ferguson, D. P. S.; Gao, Y. S.; González, S.; Grahl, J.; Greening, T. C.; Harton, J. L.; Hayes, O. J.; Hu, H.; McNamara, P. A.; Nachtman, J. M.; Orejudos, W.; Pan, Y. B.; Saadi, Y.; Schmitt, M.; Scott, I. J.; Sharma, V.; Turk, J. D.; Walsh, A. M.; Wu, Sau Lan; Wu, X.; Yamartino, J. M.; Zheng, M.; Zobernig, G.

    1996-03-01

    The electroweak mixing angle is determined with high precision from measurements of the mean difference between forward and backward hemisphere charges in hadronic decays of the Z. A data sample of 2.5 million hadronic Z decays recorded over the period 1990 to 1994 in the ALEPH detector at LEP is used. The mean charge separation between event hemispheres containing the original quark and antiquark is measured forbbar b andcbar c events in subsamples selected by their long lifetimes or using fast D*’s. The corresponding average charge separation for light quarks is measured in an inclusive sample from the anticorrelation between charges of opposite hemispheres and agrees with predictions of hadronisation models with a precision of 2%. It is shown that differences between light quark charge separations and the measured average can be determined using hadronisation models, with systematic uncertainties constrained by measurements of inclusive production of kaons, protons and Λ’s. The separations are used to measure the electroweak mixing angle precisely as sin2 ϑ {w/eff}=0.2322±0.0008(exp.stat.) ±0.0007(exp.syst.)±0.0008(sep.). The first two errors are due to purely experimental sources whereas the third stems from uncertainties in the quark charge separations.

  13. How might global health master deadly sins and strive for greater virtues?

    Directory of Open Access Journals (Sweden)

    Catherine Panter-Brick

    2014-03-01

    Full Text Available In the spirit of critical reflection, we examine how the field of global health might surmount current challenges and prioritize its ethical mandate, namely to achieve, for all people, equity in health. We use the parlance of mastering deadly sins and striving for greater virtues in an effort to review what is needed to transform global health action. Global health falls prey to four main temptations: coveting silo gains, lusting for technological solutions, leaving broad promises largely unfulfilled, and boasting of narrow successes. This necessitates a change of heart: to keep faith with the promise it made, global health requires a realignment of core values and a sharper focus on the primacy of relationships with the communities it serves. Based on the literature to date, we highlight six steps to re-orienting global health action. Articulating a coherent global health agenda will come from principled action, enacted through courage and prudence in decision-making to foster people-centered systems of care over the entire lifespan.

  14. Equilibrium and kinetics of Sin Nombre hantavirus binding at DAF/CD55 functionalized bead surfaces.

    Science.gov (United States)

    Buranda, Tione; Swanson, Scarlett; Bondu, Virginie; Schaefer, Leah; Maclean, James; Mo, Zhenzhen; Wycoff, Keith; Belle, Archana; Hjelle, Brian

    2014-03-10

    Decay accelerating factor (DAF/CD55) is targeted by many pathogens for cell entry. It has been implicated as a co-receptor for hantaviruses. To examine the binding of hantaviruses to DAF, we describe the use of Protein G beads for binding human IgG Fc domain-functionalized DAF ((DAF)₂-Fc). When mixed with Protein G beads the resulting DAF beads can be used as a generalizable platform for measuring kinetic and equilibrium binding constants of DAF binding targets. The hantavirus interaction has high affinity (24-30 nM; k(on) ~ 10⁵ M⁻¹ s⁻¹, k(off) ~ 0.0045 s⁻¹). The bivalent (DAF)₂-Fc/SNV data agree with hantavirus binding to DAF expressed on Tanoue B cells (K(d) = 14.0 nM). Monovalent affinity interaction between SNV and recombinant DAF of 58.0 nM is determined from competition binding. This study serves a dual purpose of presenting a convenient and quantitative approach of measuring binding affinities between DAF and the many cognate viral and bacterial ligands and providing new data on the binding constant of DAF and Sin Nombre hantavirus. Knowledge of the equilibrium binding constant allows for the determination of the relative fractions of bound and free virus particles in cell entry assays. This is important for drug discovery assays for cell entry inhibitors.

  15. An in-depth analysis of original antigenic sin in dengue virus infection.

    Science.gov (United States)

    Midgley, Claire M; Bajwa-Joseph, Martha; Vasanawathana, Sirijitt; Limpitikul, Wannee; Wills, Bridget; Flanagan, Aleksandra; Waiyaiya, Emily; Tran, Hai Bac; Cowper, Alison E; Chotiyarnwong, Pojchong; Chotiyarnwon, Pojchong; Grimes, Jonathan M; Yoksan, Sutee; Malasit, Prida; Simmons, Cameron P; Mongkolsapaya, Juthathip; Screaton, Gavin R

    2011-01-01

    The evolution of dengue viruses has resulted in four antigenically similar yet distinct serotypes. Infection with one serotype likely elicits lifelong immunity to that serotype, but generally not against the other three. Secondary or sequential infections are common, as multiple viral serotypes frequently cocirculate. Dengue infection, although frequently mild, can lead to dengue hemorrhagic fever (DHF) which can be life threatening. DHF is more common in secondary dengue infections, implying a role for the adaptive immune response in the disease. There is currently much effort toward the design and implementation of a dengue vaccine but these efforts are made more difficult by the challenge of inducing durable neutralizing immunity to all four viruses. Domain 3 of the dengue virus envelope protein (ED3) has been suggested as one such candidate because it contains neutralizing epitopes and it was originally thought that relatively few cross-reactive antibodies are directed to this domain. In this study, we performed a detailed analysis of the anti-ED3 response in a cohort of patients suffering either primary or secondary dengue infections. The results show dramatic evidence of original antigenic sin in secondary infections both in terms of binding and enhancement activity. This has important implications for dengue vaccine design because heterologous boosting is likely to maintain the immunological footprint of the first vaccination. On the basis of these findings, we propose a simple in vitro enzyme-linked immunosorbent assay (ELISA) to diagnose the original dengue infection in secondary dengue cases.

  16. Estudios sobre postmodernidad y estudios culturales: ¿sinónimos?

    Directory of Open Access Journals (Sweden)

    Dr. Roberto A. Follari

    2000-01-01

    Full Text Available La postmodernidad exige para ser comprendida una dimensión sociohistórica y otra filosófica que le resulta irrenunciables. También hay una serie de fenómenos propiamente culturales, que son los que los denominados "estudios culturales" (G. Canclini. M. Barbero, etc. han asumido en Latinoamérica. Tales estudios han aportado una descripción de fenómenos nuevos, que no son analizados por ningún otro discurso teórico (tribus urbanas, identidades lábiles, influencia de los medios en los nuevos estilos de consumo, etc.. Con ello se da cuenta de parte de la cuestión postmodernidad, pero sin dudase deja fuera otras: lo filosófico y aún lo social y lo político quedan fuera de esa especie de antropología del presente. Por lo tanto, un enfoque integral de lo postmoderno incluye los estudios culturales, pero está lejos de limitarse a ellos.

  17. Corrosión de armaduras galvanizadas y sin proteger embebidas en cemento aluminoso estabilizado

    Directory of Open Access Journals (Sweden)

    Triviño, F.

    1981-06-01

    Full Text Available Not available

    El cemento aluminoso, cuya obtención se basa en la fusión de bauxita y caliza, ha demostrado desde que fue patentado en Francia, en 1908 por Cementos Lafarge, unas propiedades excepcionales que lo hacen idóneo para ciertas aplicaciones. Tales propiedades son fundamentalmente el desarrollo de elevadas resistencias mecánicas en las primeras edades de hidratación, posibilidad de hormigonar en tiempo frío, una gran resistencia química al agua de mar y a los sulfatos, propiedades refractarias, etc. Todo ello hizo que el cemento aluminoso del tipo fundido, con un 40 % de Al2O3, se utilizara ampliamente en la construcción. Sin embargo, a partir de un determinado momento empezaron a observarse alteraciones en algunas obras construidas con hormigón de este tipo, manifestándose importantes pérdidas de sus resistencias mecánicas (1. Las causas de tales deterioros han sido ampliamente estudiadas (2-(13, atribuyéndose la principal a la "conversión" de los aluminatos cálcicos hidratados hexagonales en hidratos cúbicos, según reacción [1].

  18. Elevated Cytokines, Thrombin and PAI-1 in Severe HCPS Patients Due to Sin Nombre Virus

    Directory of Open Access Journals (Sweden)

    Virginie Bondu

    2015-02-01

    Full Text Available Sin Nombre Hantavirus (SNV, Bunyaviridae Hantavirus is a Category A pathogen that causes Hantavirus Cardiopulmonary Syndrome (HCPS with case fatality ratios generally ranging from 30% to 50%. HCPS is characterized by vascular leakage due to dysregulation of the endothelial barrier function. The loss of vascular integrity results in non-cardiogenic pulmonary edema, shock, multi-organ failure and death. Using Electric Cell-substrate Impedance Sensing (ECIS measurements, we found that plasma samples drawn from University of New Mexico Hospital patients with serologically-confirmed HCPS, induce loss of cell-cell adhesion in confluent epithelial and endothelial cell monolayers grown in ECIS cultureware. We show that the loss of cell-cell adhesion is sensitive to both thrombin and plasmin inhibitors in mild cases, and to thrombin only inhibition in severe cases, suggesting an increasing prothrombotic state with disease severity. A proteomic profile (2D gel electrophoresis and mass spectrometry of HCPS plasma samples in our cohort revealed robust antifibrinolytic activity among terminal case patients. The prothrombotic activity is highlighted by acute ≥30 to >100 fold increases in active plasminogen activator inhibitor (PAI-1 which, preceded death of the subjects within 48 h. Taken together, this suggests that PAI-1 might be a response to the severe pathology as it is expected to reduce plasmin activity and possibly thrombin activity in the terminal patients.

  19. ROTATION–ACTIVITY CORRELATIONS IN K AND M DWARFS. I. STELLAR PARAMETERS AND COMPILATIONS OF v sin i AND P /sin i FOR A LARGE SAMPLE OF LATE-K AND M DWARFS

    International Nuclear Information System (INIS)

    Houdebine, E. R.; Mullan, D. J.; Paletou, F.; Gebran, M.

    2016-01-01

    The reliable determination of rotation–activity correlations (RACs) depends on precise measurements of the following stellar parameters: T eff , parallax, radius, metallicity, and rotational speed v sin i . In this paper, our goal is to focus on the determination of these parameters for a sample of K and M dwarfs. In a future paper (Paper II), we will combine our rotational data with activity data in order to construct RACs. Here, we report on a determination of effective temperatures based on the ( R – I ) C color from the calibrations of Mann et al. and Kenyon and Hartmann for four samples of late-K, dM2, dM3, and dM4 stars. We also determine stellar parameters ( T eff , log( g ), and [M/H]) using the principal component analysis–based inversion technique for a sample of 105 late-K dwarfs. We compile all effective temperatures from the literature for this sample. We determine empirical radius–[M/H] correlations in our stellar samples. This allows us to propose new effective temperatures, stellar radii, and metallicities for a large sample of 612 late-K and M dwarfs. Our mean radii agree well with those of Boyajian et al. We analyze HARPS and SOPHIE spectra of 105 late-K dwarfs, and we have detected v sin i in 92 stars. In combination with our previous v sin i measurements in M and K dwarfs, we now derive P /sin i measures for a sample of 418 K and M dwarfs. We investigate the distributions of P /sin i , and we show that they are different from one spectral subtype to another at a 99.9% confidence level.

  20. Rotation-Activity Correlations in K and M Dwarfs. I. Stellar Parameters and Compilations of v sin I and P/sin I for a Large Sample of Late-K and M Dwarfs

    Science.gov (United States)

    Houdebine, E. R.; Mullan, D. J.; Paletou, F.; Gebran, M.

    2016-05-01

    The reliable determination of rotation-activity correlations (RACs) depends on precise measurements of the following stellar parameters: T eff, parallax, radius, metallicity, and rotational speed v sin I. In this paper, our goal is to focus on the determination of these parameters for a sample of K and M dwarfs. In a future paper (Paper II), we will combine our rotational data with activity data in order to construct RACs. Here, we report on a determination of effective temperatures based on the (R-I) C color from the calibrations of Mann et al. and Kenyon & Hartmann for four samples of late-K, dM2, dM3, and dM4 stars. We also determine stellar parameters (T eff, log(g), and [M/H]) using the principal component analysis-based inversion technique for a sample of 105 late-K dwarfs. We compile all effective temperatures from the literature for this sample. We determine empirical radius-[M/H] correlations in our stellar samples. This allows us to propose new effective temperatures, stellar radii, and metallicities for a large sample of 612 late-K and M dwarfs. Our mean radii agree well with those of Boyajian et al. We analyze HARPS and SOPHIE spectra of 105 late-K dwarfs, and we have detected v sin I in 92 stars. In combination with our previous v sin I measurements in M and K dwarfs, we now derive P/sin I measures for a sample of 418 K and M dwarfs. We investigate the distributions of P/sin I, and we show that they are different from one spectral subtype to another at a 99.9% confidence level. Based on observations available at Observatoire de Haute Provence and the European Southern Observatory databases and on Hipparcos parallax measurements.

  1. ROTATION–ACTIVITY CORRELATIONS IN K AND M DWARFS. I. STELLAR PARAMETERS AND COMPILATIONS OF v sin i AND P /sin i FOR A LARGE SAMPLE OF LATE-K AND M DWARFS

    Energy Technology Data Exchange (ETDEWEB)

    Houdebine, E. R. [Armagh Observatory, College Hill, BT61 9DG Armagh, Northern Ireland (United Kingdom); Mullan, D. J. [Department of Physics and Astronomy, University of Delaware, Newark, DE 19716 (United States); Paletou, F. [Université de Toulouse, UPS-Observatoire Midi-Pyrénées, IRAP, Toulouse (France); Gebran, M., E-mail: eric_houdebine@yahoo.fr [Department of Physics and Astronomy, Notre Dame University-Louaize, P.O. Box 72, Zouk Mikael (Lebanon)

    2016-05-10

    The reliable determination of rotation–activity correlations (RACs) depends on precise measurements of the following stellar parameters: T {sub eff}, parallax, radius, metallicity, and rotational speed v sin i . In this paper, our goal is to focus on the determination of these parameters for a sample of K and M dwarfs. In a future paper (Paper II), we will combine our rotational data with activity data in order to construct RACs. Here, we report on a determination of effective temperatures based on the ( R – I ){sub C} color from the calibrations of Mann et al. and Kenyon and Hartmann for four samples of late-K, dM2, dM3, and dM4 stars. We also determine stellar parameters ( T {sub eff}, log( g ), and [M/H]) using the principal component analysis–based inversion technique for a sample of 105 late-K dwarfs. We compile all effective temperatures from the literature for this sample. We determine empirical radius–[M/H] correlations in our stellar samples. This allows us to propose new effective temperatures, stellar radii, and metallicities for a large sample of 612 late-K and M dwarfs. Our mean radii agree well with those of Boyajian et al. We analyze HARPS and SOPHIE spectra of 105 late-K dwarfs, and we have detected v sin i in 92 stars. In combination with our previous v sin i measurements in M and K dwarfs, we now derive P /sin i measures for a sample of 418 K and M dwarfs. We investigate the distributions of P /sin i , and we show that they are different from one spectral subtype to another at a 99.9% confidence level.

  2. Cirugía del tronco común con y sin circulación extracorpórea

    Directory of Open Access Journals (Sweden)

    Remedios Ríos Barrera

    2006-01-01

    Conclusiones: Los resultados en ambos grupos han sido similares, por lo que, en la actualidad, la existencia de estenosis del TC no condiciona la técnica de revascularización miocárdica quirúrgica con o sin CEC, quedando su elección a criterio del cirujano.

  3. MODIS/Aqua Land Surface Temperature/3-Band Emissivity 8-Day L3 Global 1km SIN Grid V006

    Data.gov (United States)

    National Aeronautics and Space Administration — MODIS/Aqua Land Surface Temperature/3-Band Emissivity 8-Day L3 Global 1km SIN Grid (MYD21A2.006). A new suite of MODIS Land Surface Temperature (LST) and Emissivity...

  4. MODIS/Terra Land Surface Temperature/3-Band Emissivity 8-Day L3 Global 1km SIN Grid V006

    Data.gov (United States)

    National Aeronautics and Space Administration — MODIS/Terra Land Surface Temperature/3-Band Emissivity 8-Day L3 Global 1km SIN Grid (MOD21A2.006). A new suite of MODIS Land Surface Temperature (LST) and Emissivity...

  5. Evidence of surface loss as ubiquitous limiting damping mechanism in SiN micro- and nanomechanical resonators

    DEFF Research Database (Denmark)

    Villanueva, Luis Guillermo; Schmid, Silvan

    2014-01-01

    Silicon nitride (SiN) micro- and nanomechanical resonators have attracted a lot of attention in various research fields due to their exceptionally high quality factors (Qs). Despite their popularity, the origin of the limiting loss mechanisms in these structures has remained controversial. In thi...

  6. EFECTOS DEL ENRIQUECIMIENTO CON SELENIO EN SPAD, CALIDAD DE LA FRUTA Y PARÁMETROS DE CRECIMIENTO DE PLANTAS DE FRESA EN UN SISTEMA DE CULTIVO SIN SUELO

    Directory of Open Access Journals (Sweden)

    PEDRO PALENCIA

    2016-02-01

    Full Text Available RESUMEN El selenio (Se es un elemento traza esencial no solo para animales, plantas y microorganismos, sino también para la salud de las personas. Por ello, parece que aumentar las cantidades de selenio en plantas puede tener implicaciones positivas. El objetivo de este trabajo fue determinar en un sistema de cultivo sin suelo con fibra de coco el efecto del selenito (Se IV y selenato (Se VI en el peso, calidad de las frutas de fresa, así como en variables de crecimiento y contenido de clorofilas de las hojas jóvenes y adultas de la planta de fresa de la variedad ‘Splendor’. Los tratamientos fueron: T1 Se(IVF (foliar, T2 Se(IVS (sustrato, T3 Se(VIF, T4 Se(VIS y T5 control (sin aporte de Se. Se aplicaron semanalmente las mismas concentraciones de Se(IV y Se(VI. Los resultados del análisis mostraron que el efecto de los tratamientos sobre firmeza, sólidos solubles totales y acidez titratable en frutas fue significativo. Los valores más altos de firmeza y sólidos solubles fueron mostrados por el tratamiento T4. Los mayores valores para el pH se producen en los tratamientos con T2 y T4. Los resultados indican que el Se tiene un efecto positivo sobre los valores de SPAD en hoja vieja. Las plantas con tratamiento de selenio presentaron un mayor número de hojas en relación a las plantas control.

  7. Environmental characterization of the reproductive season of migratory fish of the Sinú river (Córdoba, Colombia

    Directory of Open Access Journals (Sweden)

    Eduardo Kerguelén-Durango

    2015-09-01

    Full Text Available Objective. To characterize some abiotic factors during the reproductive season of migratory fish (bocachico Prochilodus magdalenae, dorada Brycon sinuensis, bagre blanco Sorubim cuspicaudus and barbul Pimelodus blochii in the Sinú River. Materials and methods. From April to October, 2008, in Carrizola (Tierralta, 36.31 km from the Urrá hydroelectric plant factors such as flow=Qriver, daily flow difference =ΔQriver, velocity=Vriver, temperature=Triver, electrical conductivity=CE, total dissolved solids=STD, turbidity=Turb, cloudiness=Nub, rainfall=Pluv and solar brightness=Bs were measured daily three times/day (07:00 h, 12:00 h, 17:00 h. Also, on the same schedule, ichthyoplankton was collected as an indicator of reproductive activity, assessed by reproductive frequency (Fr=number of days with presence of ichthyoplankton/number of days in the period evaluated X 100 and larval density (Dl=larval/m3. Results. The daily values of Qriver ranged between 278.7 and 838.5 m3/s, ΔQriver between 0.0 and 100.7 m3/s, Vriver between 1.40 and 1.53 m/s, Pluv between 0.0 and 88.2 mm, Triver between 27.0 and 28.7°C, STD between 73.0 and 302.3 mg/L, Turb between 9.7 and 679.7 NTU, CE between 81.0 and 361.7 mS/cm, Bs between 0.0 and 11.2 hours, Nub between 2.0 and 7.3 octaves. The Fr was 30.4%, with April (40.0% and May (74.2% as the higher activity reproductive months, while the Dl in the season was 4.9 larvae/m3, with the larvae group other species (2.9 larvae/m3 and bocachico (1.8 larvae/m3 as the most abundant. Conclusions. Most reproductive activity was recorded early in the season (April and May and parameters such as Qriver, Triver, Vriver, Pluv, STD and Nub may be considered final factors associated with migratory fish reproduction.

  8. Faustina Sáez de Melgar: liberación sin rupturas

    Directory of Open Access Journals (Sweden)

    Dorado, Carlos

    2014-06-01

    Full Text Available Drawing on periodicals as the principal documental source, this article aims to demonstrate how the copious literary production and biography of Faustina Sáez de Melgar (1833? was closely linked to journalism. The creator of several magazines aimed at women, she seems to regard fashion magazines as a way of encouraging reading habits in the home. She asserts that education is the key to delivering women from their social marginalisation, which she denounced as a form of slavery. Although an active supporter of abolitionism -author of the drama La cadena rota- she did not consider women’s liberation to require any break in social norms, as it can be found within marriage, the maintaining of patriarchal structures and the practising of Christian virtues. Her thought sometimes appears opportunistic and contradictory. This is possibly a result of a cautious strategy, in which she sought to achieve only what was possible in her epoch.Con documentación hemerográfica como fuente principal, el artículo pretende poner de manifiesto la estrecha relación que con la prensa tuvo la extensa obra y la biografía de Faustina Sáez de Melgar (1833?. Creadora de varias revistas dirigidas a la mujer, vio en ellas un medio de fomentar la lectura en los hogares. Afirma que la educación es el medio por el que la mujer puede liberarse de la marginación social que padece y que ella denuncia como esclavitud. Autora del drama La cadena rota, comprometida con el abolicionismo, considera sin embargo innecesario romper ninguna: esa liberación llega además por el matrimonio y la práctica de las virtudes en una sociedad patriarcal cristiana. Sus opiniones parecen en ocasiones contradictorias y oportunistas. Posiblemente subyace una cautelosa estrategia en aplicación del “posibilismo”.

  9. Tecnologías emergentes para la conservación de alimentos sin calor

    Directory of Open Access Journals (Sweden)

    Fernández Molina, Juan José

    2001-01-01

    Full Text Available Not available

    Se han investigado los principios básicos de tres tecnologías emergentes para pasteurizar y esterilizar alimentos sin empleo del calor Mediante numerosos estudios se ha comprobado la efectividad de los campos eléctricos pulsantes de alta intensidad (CEPAI, los pulsos de luz (PL y los campos magnéticos oscilantes (CMO en la destrucción de microorganismos y enzimas de sistemas alimentarios. En la inactivación microbiana por CEPA!, el blanco principal es la membrana celular que, al ser sometida a campos eléctricos de alta intensidad, se hace permeable formando huecos o poros cuyo tamaño se incrementa a medida que aumenta la intensidad del campo eléctrico o el tiempo de tratamiento o se reduce la resistencia iónica del medio de pulsación. Por otra parte, los PL inducen reacciones fotoquímicas y fototérmicas en los alimentos, causando la muerte de gran cantidad de microorganismos, especialmente en productos alimenticios envasados. Los CMO producen simulación o inhibición en el crecimiento y reproducción de los microorganismos, un simple pulso de intensidad de 5-10 teslas y frecuencias de 5-500 kHz es suficiente para reducir el número de microorganismos en un mínimo de 2 ciclos logarítmicos. Se ha comprobado que estas tecnologías alargan la vida de anaquel de diversos productos alimenticios y pueden ser consideradas como sustitutos parciales de los procesos convencionales de pasteurización y esterilización de alimentos por tratamientos térmicos.

  10. ¿Al final, TLC con o sin biopiratería?

    Directory of Open Access Journals (Sweden)

    Martha Isabel Gómez Lee

    2006-01-01

    Full Text Available El problema está en que en Colombia los temas de acceso a los recursos genéticos, los derechos de propiedad intelectual (DPI y la protección del conocimiento tradicional (CT no han recibido la importancia que se merecen. No ha habido un debate abierto acerca del papel que juegan estos temas en el desarrollo de un país megadiverso y una nación multiétnica y pluricultural, como es Colombia. Sin embargo, el gobierno colombiano decidió negociar un TLC indefinido que define la política comercial al respecto para Colombia. En febrero de 2006, se cerraron las negociaciones del TLC en términos similares a Perú. Ese país aceptó las patentes de genes aislados y de plantas conforme a los intereses de Estados Unidos. Colombia tiene cuatro grupos étnicos: 84 pueblos indígenas que hablan 64 lenguas, los afrocolombianos, los raizales del Archipiélago de San Andrés y Providencia y los rom. La constitución de 1991 garantiza y protege los recursos genéticos, la diversidad étnica y cultural y los derechos humanos. Las posiciones y propuestas oficiales sobre acceso a recursos genéticos, biodiversidad y protección del CT que presentó el gobierno colombiano en el TLC, no fueron concertadas previamente con los grupos étnicos colombianos. El Estado tiene que consultarlos, para determinar su posición respecto al acceso a los recursos genéticos, la protección al CT y los DPI

  11. THE SINS/zC-SINF SURVEY of z {approx} 2 GALAXY KINEMATICS: OUTFLOW PROPERTIES

    Energy Technology Data Exchange (ETDEWEB)

    Newman, Sarah F.; Genzel, Reinhard [Department of Astronomy, Campbell Hall, University of California, Berkeley, CA 94720 (United States); Foerster-Schreiber, Natascha M.; Buschkamp, Peter; Davies, Ric; Eisenhauer, Frank; Kurk, Jaron; Lutz, Dieter [Max-Planck-Institut fuer extraterrestrische Physik (MPE), Giessenbachstr.1, D-85748 Garching (Germany); Griffin, Kristen Shapiro [Space Sciences Research Group, Northrop Grumman Aerospace Systems, Redondo Beach, CA 90278 (United States); Mancini, Chiara; Renzini, Alvio [Osservatorio Astronomico di Padova, Vicolo dellOsservatorio 5, Padova, I-35122 (Italy); Lilly, Simon J.; Carollo, C. Marcella; Peng, Yingjie [Institute of Astronomy, Department of Physics, Eidgenoessische Technische Hochschule, ETH Zuerich, CH-8093 (Switzerland); Bouche, Nicolas [Institut de Recherche en Astrophysique et Planetologie (IRAP), Universite de Toulouse, UPS-OMP, IRAP, 14, avenue Edouard Berlin, F-31400 Toulouse (France); Burkert, Andreas [Department fuer Physik, Universitaets-Sternwarte Ludwig-Maximilians-Universitaet (USM), Scheinerstr. 1, Muenchen, D-81679 (Germany); Cresci, Giovanni [Istituto Nazionale di AstrofisicaOsservatorio Astronomico di Arcetri, Largo Enrico Fermi 5, I-50125 Firenze (Italy); Genel, Shy [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Hicks, Erin K. S. [Department of Astronomy, University of Washington, Box 351580, U.W., Seattle, WA 98195-1580 (United States); Naab, Thorsten, E-mail: sfnewman@berkeley.edu [Max-Planck Institute for Astrophysics, Karl Schwarzschildstrasse 1, D-85748 Garching (Germany); and others

    2012-12-10

    Using SINFONI H{alpha}, [N II], and [S II] AO data of 27 z {approx} 2 star-forming galaxies (SFGs) from the SINS and zC-SINF surveys, we explore the dependence of outflow strength (via the broad flux fraction) on various galaxy parameters. For galaxies that have evidence for strong outflows, we find that the broad emission is spatially extended to at least the half-light radius ({approx}a few kpc). Decomposition of the [S II] doublet into broad and narrow components suggests that this outflowing gas probably has a density of {approx}10-100 cm{sup -3}, less than that of the star-forming gas (600 cm{sup -3}). There is a strong correlation of the H{alpha} broad flux fraction with the star formation surface density of the galaxy, with an apparent threshold for strong outflows occurring at 1 M{sub Sun} yr{sup -1} kpc{sup -2}. Above this threshold, we find that SFGs with log m{sub *} > 10 have similar or perhaps greater wind mass-loading factors ({eta} = M-dot{sub out}/SFR) and faster outflow velocities than lower mass SFGs, suggesting that the majority of outflowing gas at z {approx} 2 may derive from high-mass SFGs. The mass-loading factor is also correlated with the star formation rate (SFR), galaxy size, and inclination, such that smaller, more star-forming, and face-on galaxies launch more powerful outflows. We propose that the observed threshold for strong outflows and the observed mass loading of these winds can be explained by a simple model wherein break-out of winds is governed by pressure balance in the disk.

  12. Total parenteral nutrition - infants

    Science.gov (United States)

    ... medlineplus.gov/ency/article/007239.htm Total parenteral nutrition - infants To use the sharing features on this page, please enable JavaScript. Total parenteral nutrition (TPN) is a method of feeding that bypasses ...

  13. Total parenteral nutrition

    Science.gov (United States)

    ... medlineplus.gov/ency/patientinstructions/000177.htm Total parenteral nutrition To use the sharing features on this page, please enable JavaScript. Total parenteral nutrition (TPN) is a method of feeding that bypasses ...

  14. Technique of total thyroidectomy

    International Nuclear Information System (INIS)

    Rao, R.S.

    1999-01-01

    It is essential to define the various surgical procedures that are carried out for carcinoma of the thyroid gland. They are thyroid gland, subtotal lobectomy, total thyroidectomy and near total thyroidectomy

  15. Total iron binding capacity

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/003489.htm Total iron binding capacity To use the sharing features on this page, please enable JavaScript. Total iron binding capacity (TIBC) is a blood test to ...

  16. Total well dominated trees

    DEFF Research Database (Denmark)

    Finbow, Arthur; Frendrup, Allan; Vestergaard, Preben D.

    cardinality then G is a total well dominated graph. In this paper we study composition and decomposition of total well dominated trees. By a reversible process we prove that any total well dominated tree can both be reduced to and constructed from a family of three small trees....

  17. Estudio prospectivo randomizado sobre el uso de drenaje vs. no drenaje en artroplastia total de rodilla. [Prospective randomized study on the use of drainage in total knee arthroplasty.

    Directory of Open Access Journals (Sweden)

    Matias Pereira Duarte

    2015-09-01

    Full Text Available Introducción La utilización de drenaje en la artroplastia total de rodilla es una práctica ampliamente aceptada en la comunidad ortopédica; sin embargo, en la bibliografía, no se encuentra evidencia concluyente sobre su beneficio. El propósito de este estudio fue comparar dos grupos de pacientes sometidos a artroplastia total de rodilla         primaria con drenaje y sin él. Materiales y Métodos Se llevó a cabo un estudio prospectivo aleatorizado en el que se realizaron 76 artroplastias totales de rodilla primarias; se dividió a los pacientes en dos grupos: grupo A, con drenaje y grupo B, sin drenaje. Se evaluaron el número de unidades de sangre transfundidas, el débito de sangre en los pacientes con drenaje, las complicaciones posoperatorias y el tiempo de hospitalización. Antes de la cirugía y después de ella, se registró el diámetro del muslo, el rango de movilidad, el hematocrito y la hemoglobina en ambos grupos. Resultados No se hallaron diferencias estadísticamente significativas en el diámetro del muslo, el rango de movilidad, el hematocrito, la hemoglobina, el número de transfusiones y la estadía hospitalaria. El número de complicaciones en el grupo B (sin drenaje fue mayor (p = 0,019: dos infecciones profundas, dos casos de celulitis, uno de flictena, una fractura de cadera, una trombosis venosa superficial, una trombosis venosa profunda y un tromboembolismo pulmonar. Conclusión Los pacientes sin drenaje posoperatorio sufrieron más complicaciones.

  18. Centering Panama in Global Modernity: The Search for National Identity and the Imagining of the Orient in Rogelio Sinán’s “Sin novedad en Shanghai”

    Directory of Open Access Journals (Sweden)

    Junyoung Verónica Kim

    2013-06-01

    Full Text Available Since its independence from Colombia in 1903 backed by the United States government, which resulted in a treaty that granted the US free rein to build, administer and control what would be known as the Panama Canal, Panama’s quest for modern nationhood has been severely called into question. More often than not it is posited as an artificial state with little organic unity and limited sovereignty: a state that is literally made in the USA. Panamanian intellectuals, such as Rogelio Sinán, responded to these discourses on the Panamanian nation-state by actively constructing a Panamanian national identity, and by calling attention to the central significance of Panama in the twentieth-century world of global modernity. Questioning the widespread narrative of Panama as a peripheral North American neo-colony that was at best a marginal actor in international history, Sinán positioned Panama at the center of the modern world where World Wars, international migrations and global capitalism connected. By exploring Sinán’s short story “Sin novedad en Shanghai” that takes place in East Asia during World War II, this study argues that the writer’s deployment of the Orient—as a geopolitical, cultural, symbolic and imaginary space—allows him to reposition Panama. In its symbolic relation to this Orient, Panama emerges not as the backwaters of global modernity, but at its center—a cosmopolis between the Orient and the Occident that reveals a microcosm of the modern world.

  19. Variables socionutricionales de hogares mazahuas integrados por preescolares desnutridos con madres con obesidad y sin obesidad

    Directory of Open Access Journals (Sweden)

    Conzuelo González, Viridiana Vanessa

    2009-01-01

    Full Text Available El primer objetivo fue conocer cuántos menores de cinco años con diferentes grados de desnutrición tienen una madre con sobrepeso/obesidad/ en una comunidad indígena que vive en extrema pobreza y bajo condiciones de migración masculina internacional. El segundo fue comparar tres variables socionutricionales (ingreso familiar, educación de la madre y adecuación nutrimental de la dieta diaria entre estos hogares y los hogares con desnutrición infantil y madres sin obesidad. Se realizó un estudio transversal (2006-2007, en la comunidad mazahua de San Francisco Tepeolulco, Municipio de Temascalcingo; que incluyó a 85 hogares integrados por preescolares con desnutrición inscritos al programa Oportunidades. Se determinó el estado nutrición de los preescolares con indicadores antropométricos y se obtuvo el IMC de las madres de estos infantes. Se aplicó una encuesta socionutricional, incluida el recordatorio de 24 horas, y complementado con la observación participante (cualitativa. Se encontró que 83% de las madres mazahuas presentaron sobrepeso u obesidad. El estado de nutrición de los preescolares con madres con obesidad presentó un porcentaje mayor de desnutrición (76%. En la variable género, se encontró que 54% de los niños con madres con obesidad tenía baja talla. Al relacionar el nivel educativo de la madre, esta variable resultó ser estadísticamente significativa (p=0.015, donde el analfabetismo está más relacionado con la desnutrición infantil que tienen madres de bajo y/o peso normal. La elevada prevalencia de hogares conformados con preescolares con desnutrición y madres con obesidad, es un síntoma más de la pobreza en zonas indígenas en México, con bajo índice de desarrollo humano.

  20. La persistencia bacteriana: una problemática ignorada por una ciencia sin respuestas

    Directory of Open Access Journals (Sweden)

    FORMENTINI E

    2017-09-01

    Full Text Available ARTÍCULO DE OPINIÓN. En nuestra cultura occidental tenemos un concepto triunfalista y mesiánico de la ciencia, ya que se confía que tarde o temprano la misma hallará respuestas y soluciones a los problemas del hombre. Sin embargo, la ciencia tiende a negar sistemáti-camente todo aquello para lo cual no tiene explicación y condena al olvido a todo conocimiento para lo cual no tiene aplicación actual. Las bacterias persistentes son uno de esos problemas olvidados, que recientemente ha despertado interés en la comunidad científica, al tener que enfrentarse a la problemática creciente de la resistencia bacteriana. Este artículo trata dos temas disímiles pero que están estrechamente relacionados. El primero, consiste en explicar el ignorado y olvidado fenómeno de la persistencia bacteriana y su impli-cancia en la progresiva disminución de la vida útil de los antibióticos. El segundo, es un análisis epistémico-ético con el objetivo de dilucidar la responsabilidad de la ciencia respecto de la ignorancia y el olvido de esta problemática. Finalmente se propone una pos-tura epistemológica para la revalorización constante de los conocimientos olvidados. SUMMARY. Bacterial persistence: an ignored problem by a science without answers. In our western culture, we have a triumphalist and messianic conception of science, since it is confided that sooner or later it will find the answers and the solutions to the problems of humanity. However, science tends to systematically ignore everything for which it has no explanation, and condemns to oblivion all knowledge that has not practical application. Persister cells are one of those forgotten problems, although it has recently attracted the attention of the scientific community, as it is associated with the growing problem of bacterial resistance. This article addresses two dissimilar but closely related topics. The first is to explain the forgotten and ignored phenomenon of persister cells

  1. Máximos y mínimos sin cálculo aplicado a la economía

    Directory of Open Access Journals (Sweden)

    Luis Miguel Cabrera G.

    2015-04-01

    Full Text Available RESUMEN El articulo muestra los problemas más sencillos “Máximos y Mínimos sin Cálculo”. Este tipo de problemas se presentan en ingeniería, la industria, la administración y la vida cotidiana, con una característica en común, no obstante sus diferencias. Esta característica, consiste en determinar la forma  de lograr un efecto óptimo mediante la selección de una entre varias posibilidades. Estos problemas se resuelve por medio de métodos  de cálculo diferencial, pero solo pueden ser calculados únicamente, con la ayuda del álgebra elemental. Este es, precisamente el contenido del artículo, que propone métodos más sencillos, sin la aplicación del cálculo diferencial.

  2. Influencia de los trastornos mentales y de la personalidad en el abandono de procesos en personas sin hogar

    Directory of Open Access Journals (Sweden)

    Carlos Salavera

    2014-01-01

    Full Text Available Las personas sin hogar protagonizan un alto índice de abandonos en los procesos terapéuticos que establecen. El motivo de abandono no siempre es conocido, en esta investigación se aborda si viene mediado por los trastornos mentales o son los trastornos de personalidad los que llevan un mayor peso. Los resultados muestran a las personas sin hogar con deterioro cognitivo leve y trastornos de personalidad del grupo de problemas interpersonales y ambivalentes como los principales candidatos al abandono de procesos de corte psicosocial. Esto implica la necesidad de tener en cuenta estos trastornos en el tratamiento y desarrollo de programas específicos de intervención.

  3. GaN-based FETs using Cat-CVD SiN passivation for millimeter-wave applications

    International Nuclear Information System (INIS)

    Higashiwaki, Masataka; Mimura, Takashi; Matsui, Toshiaki

    2008-01-01

    We have found that SiN passivation by catalytic chemical vapor deposition (Cat-CVD) can significantly increase an electron density of an AlGaN/GaN heterostructure field-effect transistor (HFET). This effect enables thin-barrier HFET structures to have a high-density two-dimensional electron gas and leads to suppression of short-channel effects. We fabricated 30-nm-gate Al 0.4 Ga 0.6 N(8 nm)/GaN HFETs using Cat-CVD SiN. The maximum drain current density and extrinsic transconductance were 1.49 A/mm and 402 mS/mm, respectively. Current-gain cutoff frequency and maximum oscillation frequency of the HFETs were 181 and 186 GHz, respectively. These high-frequency device characteristics are sufficiently high enough for millimeter-wave applications

  4. Meningitis neumocócica en un lactante curada sin secuelas neurológicas ni neuroquirúrgicas

    Directory of Open Access Journals (Sweden)

    C. Lamote de Grignon

    1953-03-01

    Full Text Available Lactante de 45 días, en pésimas condiciones fisiológicas, que presenta una meningitis neumocócica indiscutible. Es tratada con sulfatiazol y penicilina (apenas por vía intratecal. Cura prácticamente a los 17 días sin secuela alguna. A los 8 meses se mantenía bien desde todos los puntos de vista.

  5. Hamster-Adapted Sin Nombre Virus Causes Disseminated Infection and Efficiently Replicates in Pulmonary Endothelial Cells without Signs of Disease

    OpenAIRE

    Safronetz, David; Prescott, Joseph; Haddock, Elaine; Scott, Dana P.; Feldmann, Heinz; Ebihara, Hideki

    2013-01-01

    To date, a laboratory animal model for the study of Sin Nombre virus (SNV) infection or associated disease has not been described. Unlike infection with Andes virus, which causes lethal hantavirus pulmonary syndrome (HPS)-like disease in hamsters, SNV infection is short-lived, with no viremia and little dissemination. Here we investigated the effect of passaging SNV in hamsters. We found that a host-adapted SNV achieves prolonged and disseminated infection in hamsters, including efficient rep...

  6. Measurement of $sin2\\beta$ from $B^{0}_{d} \\rightarrow J/\\Psi K^{0}_{S}$ with the LHCb detector

    CERN Document Server

    Mangiafave, N; Calvi, M; Matteuzzi, C

    2008-01-01

    The LHCb experiment will study CP violation and rare B meson decays at the LHC accelerator, in the CERN laboratories of Geneva. The CP violation in the $b$ quark mesons was observed for the first time measuring the $\\sin2\\beta$ parameter. In the first year of data taking at LHCb the $\\sin2\\beta$ measurement will be performed in the channel $B_d ^0 \\rightarrow J/\\psi K_S ^0$ (called golden channel). The comparison with results obtained in previous experiments will show possible systematic errors. Once the systematic errors will be understood, the possible discrepancies with the expected results will be the sign of a new physics beyond the Standard Model. $\\sin2\\beta$ is extracted from the asymmetry in the decay $B_d ^0 \\rightarrow J/\\psi(\\mu^+\\mu^-) K_S ^0 (\\pi^+\\pi^-)$ and its CP conjugated $\\overline{B}_d ^0 \\rightarrow J/\\psi(\\mu^-\\mu^+) K_S ^0(\\pi^-\\pi^+)$. To distinguish between $B_d ^0$ and $\\overline{B}_d$ flavour tagging algorithms are used. These introduce an additional parameter: the wrong tag fracti...

  7. Maximum Correntropy Unscented Kalman Filter for Ballistic Missile Navigation System based on SINS/CNS Deeply Integrated Mode.

    Science.gov (United States)

    Hou, Bowen; He, Zhangming; Li, Dong; Zhou, Haiyin; Wang, Jiongqi

    2018-05-27

    Strap-down inertial navigation system/celestial navigation system ( SINS/CNS) integrated navigation is a high precision navigation technique for ballistic missiles. The traditional navigation method has a divergence in the position error. A deeply integrated mode for SINS/CNS navigation system is proposed to improve the navigation accuracy of ballistic missile. The deeply integrated navigation principle is described and the observability of the navigation system is analyzed. The nonlinearity, as well as the large outliers and the Gaussian mixture noises, often exists during the actual navigation process, leading to the divergence phenomenon of the navigation filter. The new nonlinear Kalman filter on the basis of the maximum correntropy theory and unscented transformation, named the maximum correntropy unscented Kalman filter, is deduced, and the computational complexity is analyzed. The unscented transformation is used for restricting the nonlinearity of the system equation, and the maximum correntropy theory is used to deal with the non-Gaussian noises. Finally, numerical simulation illustrates the superiority of the proposed filter compared with the traditional unscented Kalman filter. The comparison results show that the large outliers and the influence of non-Gaussian noises for SINS/CNS deeply integrated navigation is significantly reduced through the proposed filter.

  8. The devil is in the details: the seven deadly sins of organizing and continuing interprofessional education in the US.

    Science.gov (United States)

    Clark, Phillip G

    2011-09-01

    In spite of increased calls for expanding interprofessional practice (IPP) in the US health care system to address concerns about patient safety and quality of care, there has not been a corresponding dramatic growth in interprofessional education (IPE) programs. Indeed, the history of IPE in the US has been a roller-coaster ride of gains and losses, successes and failures. Understanding why this has been so requires the development of a personal and political economy framework, based on an understanding of the structural, ideological, and economic factors and forces that characterize IPE in American higher education. Using a metaphor of the seven deadly sins (lust, pride, greed, gluttony, envy, sloth, and wrath), this discussion focuses on both things that should not be done (sins of commission) and those that should be done but are not (sins of omission) to create successful and sustainable IPE programs. Taken together, these factors help to frame a perspective on IPE that highlights the essential knowledge, attitudes, and skills needed by faculty and administrators to create, implement, and - most importantly - sustain successful programs. Implications of this framework for promoting increased IPE are discussed, particularly with respect to insuring its successful continuation into the future.

  9. Los procesos de exclusión social de las personas sin hogar en la ciudad de Barcelona

    Directory of Open Access Journals (Sweden)

    María Virginia Matulic-Domandzic

    2013-12-01

    Full Text Available En este artículo se abordan los procesos de exclusión social de las personas sin hogar en la ciudad de Barcelona a través de tres apartados. En primer lugar se realiza una aproximación a los procesos de exclusión social presentes en las sociedades europeas, seguidamente se centra la mirada en la dimensión conceptual de las personas sin hogar y en sus principales causas, para finalizar con unas conclusiones en donde se sintetizan los temas planteados, así como los retos de futuro que se presentan en este fenémeno. El contenido del artículo forma parte del trabajo de investigación que se está realizando sobre los procesos de inclusión de las personas sin hogar en Barcelona. Dicha investigación está vinculada al Doctorado "Educación y sociedad" de la Universidad de Barcelona, a través del Departamento de Trabajo Social y Servicios Sociales. El incremento del fenómeno del sinhogarismo responde a procesos macrosociales que han caracterizado a las sociedades posfordistas de las últimas décadas donde la fragilidad de las redes de apoyo y de los sistemas de proteción social tienen una importancia crucial.

  10. A Method for SINS Alignment with Large Initial Misalignment Angles Based on Kalman Filter with Parameters Resetting

    Directory of Open Access Journals (Sweden)

    Xixiang Liu

    2014-01-01

    Full Text Available In the initial alignment process of strapdown inertial navigation system (SINS, large initial misalignment angles always bring nonlinear problem, which causes alignment failure when the classical linear error model and standard Kalman filter are used. In this paper, the problem of large misalignment angles in SINS initial alignment is investigated, and the key reason for alignment failure is given as the state covariance from Kalman filter cannot represent the true one during the steady filtering process. According to the analysis, an alignment method for SINS based on multiresetting the state covariance matrix of Kalman filter is designed to deal with large initial misalignment angles, in which classical linear error model and standard Kalman filter are used, but the state covariance matrix should be multireset before the steady process until large misalignment angles are decreased to small ones. The performance of the proposed method is evaluated by simulation and car test, and the results indicate that the proposed method can fulfill initial alignment with large misalignment angles effectively and the alignment accuracy of the proposed method is as precise as that of alignment with small misalignment angles.

  11. Maximum Correntropy Unscented Kalman Filter for Ballistic Missile Navigation System based on SINS/CNS Deeply Integrated Mode

    Directory of Open Access Journals (Sweden)

    Bowen Hou

    2018-05-01

    Full Text Available Strap-down inertial navigation system/celestial navigation system ( SINS/CNS integrated navigation is a high precision navigation technique for ballistic missiles. The traditional navigation method has a divergence in the position error. A deeply integrated mode for SINS/CNS navigation system is proposed to improve the navigation accuracy of ballistic missile. The deeply integrated navigation principle is described and the observability of the navigation system is analyzed. The nonlinearity, as well as the large outliers and the Gaussian mixture noises, often exists during the actual navigation process, leading to the divergence phenomenon of the navigation filter. The new nonlinear Kalman filter on the basis of the maximum correntropy theory and unscented transformation, named the maximum correntropy unscented Kalman filter, is deduced, and the computational complexity is analyzed. The unscented transformation is used for restricting the nonlinearity of the system equation, and the maximum correntropy theory is used to deal with the non-Gaussian noises. Finally, numerical simulation illustrates the superiority of the proposed filter compared with the traditional unscented Kalman filter. The comparison results show that the large outliers and the influence of non-Gaussian noises for SINS/CNS deeply integrated navigation is significantly reduced through the proposed filter.

  12. Freedom in responsibility: on the relevance of "sin" as a hermeneutic guiding principle in bioethical decision making.

    Science.gov (United States)

    Gräb-Schmidt, Elisabeth

    2005-08-01

    This essay deals with questions of responsibility concerning technology, in particular, gene technology and the special problem of research on embryos. I raise issues concerning the extent of humans' authority to act and the limits of human freedom. In what way is that freedom given, and what kind of responsibility results from it? By discussing various concepts of human freedom in the tradition of European philosophy, as juxtaposed to the Protestant understanding of freedom, this essay discusses the restricting limits, and the obligation to take responsibility. It will turn out that the question concerning freedom cannot be answered without understanding what being human involves. From a Christian perspective, this implies that the foundational relationship between human freedom and sin will be central to an assessment of the human ability to take responsibility. By obliterating the limits of human freedom, sin jeopardizes the very essence of that freedom. The project of taking into account the sinful state of the human condition thus aims at developing a realistic picture of the authority of humans in action, even in view of the human tasks of promoting science and research.

  13. Determination of wafer bonding mechanisms for plasma activated SiN films with x-ray reflectivity

    Energy Technology Data Exchange (ETDEWEB)

    Hayashi, S [Department of Materials Science and Engineering, University of California, Los Angeles, CA 90095 (United States); Sandhu, R [Department of Materials Science and Engineering, University of California, Los Angeles, CA 90095 (United States); Wojtowicz, M [Northrop Grumman Space Technology, Redondo Beach, CA 90278 (United States); Sun, Y [Department of Chemical Engineering, University of California, Los Angeles, CA 90095 (United States); Hicks, R [Department of Chemical Engineering, University of California, Los Angeles, CA 90095 (United States); Goorsky, M S [Department of Materials Science and Engineering, University of California, Los Angeles, CA 90095 (United States)

    2005-05-21

    Specular and diffuse x-ray reflectivity measurements were employed for wafer bonding studies of surface and interfacial reactions in {approx}800 A thick SiN films deposited on III-V substrates. CuK{sub {alpha}}{sub 1} radiation was employed for these measurements. The as-deposited films show very low surface roughness and uniform, high density SiN. Reflectivity measurements show that an oxygen plasma treatment converts the nitride surface to a somewhat porous SiO{sub x} layer (67 A thick, at 80% of SiO{sub 2} density), with confirmation of the oxide formation from x-ray photoelectron spectroscopy. Reactions at the bonded interface of two oxygen plasma treated SiN layers were examined using a bonded structure from which one of the III-V wafers is removed. Reflectivity measurements of bonded structures annealed at 150 deg. C and 300 deg. C show an increase in the SiO{sub x} layer density and thickness and even a density gradient across this interface. The increase in density is correlated with an increase in bond strength, where after the 300 deg. C anneal, a high interfacial bond strength, exceeding the bulk strength, was achieved.

  14. Total Quality Leadership

    Science.gov (United States)

    1991-01-01

    More than 750 NASA, government, contractor, and academic representatives attended the Seventh Annual NASA/Contractors Conference on Quality and Productivity. The panel presentations and Keynote speeches revolving around the theme of total quality leadership provided a solid base of understanding of the importance, benefits, and principles of total quality management (TQM). The presentations from the conference are summarized.

  15. Genoptraening efter total knaealloplastik

    DEFF Research Database (Denmark)

    Holm, Bente; Kehlet, Henrik

    2009-01-01

    The short- and long-term benefits of post-discharge physiotherapy regimens after total knee arthroplasty are debatable. A national survey including hospitals in Denmark that perform total knee arthroplasty showed a large variability in indication and regimen for post-knee arthroplasty...

  16. Chick Hairy1 protein interacts with Sap18, a component of the Sin3/HDAC transcriptional repressor complex

    Directory of Open Access Journals (Sweden)

    Andrade Raquel P

    2007-07-01

    Full Text Available Abstract Background The vertebrate adult axial skeleton, trunk and limb skeletal muscles and dermis of the back all arise from early embryonic structures called somites. Somites are symmetrically positioned flanking the embryo axial structures (neural tube and notochord and are periodically formed in a anterior-posterior direction from the presomitic mesoderm. The time required to form a somite pair is constant and species-specific. This extraordinary periodicity is proposed to depend on an underlying somitogenesis molecular clock, firstly evidenced by the cyclic expression of the chick hairy1 gene in the unsegmented presomitic mesoderm with a 90 min periodicity, corresponding to the time required to form a somite pair in the chick embryo. The number of hairy1 oscillations at any given moment is proposed to provide the cell with both temporal and positional information along the embryo's anterior-posterior axis. Nevertheless, how this is accomplished and what biological processes are involved is still unknown. Aiming at understanding the molecular events triggered by the somitogenesis clock Hairy1 protein, we have employed the yeast two-hybrid system to identify Hairy1 interaction partners. Results Sap18, an adaptor molecule of the Sin3/HDAC transcriptional repressor complex, was found to interact with the C-terminal portion of the Hairy1 protein in a yeast two-hybrid assay and the Hairy1/Sap18 interaction was independently confirmed by co-immunoprecipitation experiments. We have characterized the expression patterns of both sap18 and sin3a genes during chick embryo development, using in situ hybridization experiments. We found that both sap18 and sin3a expression patterns co-localize in vivo with hairy1 expression domains in chick rostral presomitic mesoderm and caudal region of somites. Conclusion Hairy1 belongs to the hairy-enhancer-of-split family of transcriptional repressor proteins. Our results indicate that during chick somitogenesis

  17. The 11S globulin Sin a 2 from yellow mustard seeds shows IgE cross-reactivity with homologous counterparts from tree nuts and peanut

    Directory of Open Access Journals (Sweden)

    Sirvent Sofía

    2012-12-01

    Full Text Available Abstract Background The 11S globulin Sin a 2 is a marker to predict severity of symptoms in mustard allergic patients. The potential implication of Sin a 2 in cross-reactivity with tree nuts and peanut has not been investigated so far. In this work, we studied at the IgG and IgE level the involvement of the 11S globulin Sin a 2 in cross-reactivity among mustard, tree nuts and peanut. Methods Eleven well-characterized mustard-allergic patients sensitized to Sin a 2 were included in the study. A specific anti-Sin a 2 serum was obtained in rabbit. Skin prick tests (SPT, enzyme-linked immunosorbent assay (ELISA, immunoblotting and IgG or IgE-inhibition immunoblotting experiments using purified Sin a 2, Sin a 1, Sin a 3, mustard, almond, hazelnut, pistachio, walnut or peanut extracts were performed. Results The rabbit anti-Sin a 2 serum showed high affinity and specificity to Sin a 2, which allowed us to demonstrate that Sin a 2 shares IgG epitopes with allergenic 11S globulins from tree nuts (almond, hazelnut, pistachio and walnut but not from peanut. All the patients included in the study had positive skin prick test to tree nuts and/or peanut and we subdivided them into two different groups according to their clinical symptoms after ingestion of such allergenic sources. We showed that 11S globulins contain conserved IgE epitopes involved in cross-reactivity among mustard, tree nuts and peanut as well as species-specific IgE epitopes. Conclusions The allergenic 11S globulin Sin a 2 from mustard is involved in cross-reactivity at the IgE level with tree nuts and peanut. Although the clinical relevance of the cross-reactive IgE epitopes present in 11S globulins needs to be investigated in further detail, our results contribute to improve the diagnosis and management of mustard allergic patients sensitized to Sin a 2.

  18. Fachada ventilada cerámica sin sub-estructuras metálicas denominado: SIERRAVENT®

    Directory of Open Access Journals (Sweden)

    Luque-Fernández, F. J.

    2011-04-01

    innovando con su nuevo producto “ SIERRAVENT® ”. El sistema patentado ha supuesto un gran impacto en el sector de la construcción, ya que permite la ejecución de una Fachada Ventilada sin la utilización de complejas estructuras metálicas ni tornillería. En el artículo se describen tanto los componentes del sistema y sus propiedades, como las características técnicas del mismo en su conjunto y los criterios para la resolución de algunos encuentros y puntos singulares. Asimismo, se hace mención a las ventajas competitivas.

  19. El movimiento de los trabajadores rurales sin tierra y la reforma agraria en Brasil

    Directory of Open Access Journals (Sweden)

    Lorenzo FERNÁNDEZ FRANCO

    2009-11-01

    Full Text Available RESUMEN: Este artículo, es un primer avance, de carácter exploratorio, de una investigación más amplia que el autor está llevando a cabo sobre el mismo tema. Centrado en el "Movimiento de los Trabajadores Rurales sin Tierra", habitualmente identificado en Brasil por las siglas MST, se contempla dicho movimiento social desde sus orígenes más remotos, al final de los años 50, hasta nuestros días situándolo, por un lado, en las transformaciones políticas y en parte sociales, y en el largo y lento proceso de una reforma agraria inconclusa, por otro. De forma descriptiva, se desarrollan, en un primer paso, los antecedentes, proceso de constitución, etapas y estructura agraria brasileña, se plantea de forma suscinta la problemática de la reforma agraria. Con estas consideraciones preliminares, siguiendo casi literalmente la formulación del propio MST, se exponen, con mayor amplitud, los objetivos y características de la Reforma Agraria desde la perspectiva de los propios trabajadores rurales. Asimismo, aunque de forma más esquemática y en base a los datos oficiales, se plantean las directrices, metas y algunas de las realizaciones del Gobierno de Fernando H. Cardoso sobre dicha reforma. En definitiva, con este artículo, se pretenden establecer las bases y los ejes analíticos necesarios para una investigación más amplia y comprensiva de este fenómeno social de masas que va más allá de la propia realidad de injusticia que se está viviendo en el mundo rural brasileño y que está contando también con un amplio y sorprendente apoyo de sectores urbanos de la población brasileña.ABSTRACT: This article is an introductory and exploratory advance of a more extensive investigation that the author is carrying out on the same subject. The research is centred on the "Movement of the Rural Workers without Land", which is ussually identified in Brazil with the initials MST. This social movement is analyzed since its remotest origins, the

  20. Laparoscopic total pancreatectomy

    Science.gov (United States)

    Wang, Xin; Li, Yongbin; Cai, Yunqiang; Liu, Xubao; Peng, Bing

    2017-01-01

    Abstract Rationale: Laparoscopic total pancreatectomy is a complicated surgical procedure and rarely been reported. This study was conducted to investigate the safety and feasibility of laparoscopic total pancreatectomy. Patients and Methods: Three patients underwent laparoscopic total pancreatectomy between May 2014 and August 2015. We reviewed their general demographic data, perioperative details, and short-term outcomes. General morbidity was assessed using Clavien–Dindo classification and delayed gastric emptying (DGE) was evaluated by International Study Group of Pancreatic Surgery (ISGPS) definition. Diagnosis and Outcomes: The indications for laparoscopic total pancreatectomy were intraductal papillary mucinous neoplasm (IPMN) (n = 2) and pancreatic neuroendocrine tumor (PNET) (n = 1). All patients underwent laparoscopic pylorus and spleen-preserving total pancreatectomy, the mean operative time was 490 minutes (range 450–540 minutes), the mean estimated blood loss was 266 mL (range 100–400 minutes); 2 patients suffered from postoperative complication. All the patients recovered uneventfully with conservative treatment and discharged with a mean hospital stay 18 days (range 8–24 days). The short-term (from 108 to 600 days) follow up demonstrated 3 patients had normal and consistent glycated hemoglobin (HbA1c) level with acceptable quality of life. Lessons: Laparoscopic total pancreatectomy is feasible and safe in selected patients and pylorus and spleen preserving technique should be considered. Further prospective randomized studies are needed to obtain a comprehensive understanding the role of laparoscopic technique in total pancreatectomy. PMID:28099344

  1. Estonian total ozone climatology

    Directory of Open Access Journals (Sweden)

    K. Eerme

    Full Text Available The climatological characteristics of total ozone over Estonia based on the Total Ozone Mapping Spectrometer (TOMS data are discussed. The mean annual cycle during 1979–2000 for the site at 58.3° N and 26.5° E is compiled. The available ground-level data interpolated before TOMS, have been used for trend detection. During the last two decades, the quasi-biennial oscillation (QBO corrected systematic decrease of total ozone from February–April was 3 ± 2.6% per decade. Before 1980, a spring decrease was not detectable. No decreasing trend was found in either the late autumn ozone minimum or in the summer total ozone. The QBO related signal in the spring total ozone has an amplitude of ± 20 DU and phase lag of 20 months. Between 1987–1992, the lagged covariance between the Singapore wind and the studied total ozone was weak. The spring (April–May and summer (June–August total ozone have the best correlation (coefficient 0.7 in the yearly cycle. The correlation between the May and August total ozone is higher than the one between the other summer months. Seasonal power spectra of the total ozone variance show preferred periods with an over 95% significance level. Since 1986, during the winter/spring, the contribution period of 32 days prevails instead of the earlier dominating 26 days. The spectral densities of the periods from 4 days to 2 weeks exhibit high interannual variability.

    Key words. Atmospheric composition and structure (middle atmosphere – composition and chemistry; volcanic effects – Meteorology and atmospheric dynamics (climatology

  2. Total photon absorption

    International Nuclear Information System (INIS)

    Carlos, P.

    1985-06-01

    The present discussion is limited to a presentation of the most recent total photonuclear absorption experiments performed with real photons at intermediate energy, and more precisely in the region of nucleon resonances. The main sources of real photons are briefly reviewed and the experimental procedures used for total photonuclear absorption cross section measurements. The main results obtained below 140 MeV photon energy as well as above 2 GeV are recalled. The experimental study of total photonuclear absorption in the nuclear resonance region (140 MeV< E<2 GeV) is still at its beginning and some results are presented

  3. [Total artificial heart].

    Science.gov (United States)

    Antretter, H; Dumfarth, J; Höfer, D

    2015-09-01

    To date the CardioWest™ total artificial heart is the only clinically available implantable biventricular mechanical replacement for irreversible cardiac failure. This article presents the indications, contraindications, implantation procedere and postoperative treatment. In addition to a overview of the applications of the total artificial heart this article gives a brief presentation of the two patients treated in our department with the CardioWest™. The clinical course, postoperative rehabilitation, device-related complications and control mechanisms are presented. The total artificial heart is a reliable implant for treating critically ill patients with irreversible cardiogenic shock. A bridge to transplantation is feasible with excellent results.

  4. Total 2004 results

    International Nuclear Information System (INIS)

    2005-02-01

    This document presents the 2004 results of Total Group: consolidated account, special items, number of shares, market environment, adjustment for amortization of Sanofi-Aventis merger-related intangibles, 4. quarter 2004 results (operating and net incomes, cash flow), upstream (results, production, reserves, recent highlights), downstream (results, refinery throughput, recent highlights), chemicals (results, recent highlights), Total's full year 2004 results (operating and net income, cash flow), 2005 sensitivities, Total SA parent company accounts and proposed dividend, adoption of IFRS accounting, summary and outlook, main operating information by segment for the 4. quarter and full year 2004: upstream (combined liquids and gas production by region, liquids production by region, gas production by region), downstream (refined product sales by region, chemicals), Total financial statements: consolidated statement of income, consolidated balance sheet (assets, liabilities and shareholder's equity), consolidated statements of cash flows, business segments information. (J.S.)

  5. Total synthesis of ciguatoxin.

    Science.gov (United States)

    Hamajima, Akinari; Isobe, Minoru

    2009-01-01

    Something fishy: Ciguatoxin (see structure) is one of the principal toxins involved in ciguatera poisoning and the target of a total synthesis involving the coupling of three segments. The key transformations in this synthesis feature acetylene-dicobalthexacarbonyl complexation.

  6. Total 2004 results

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-02-01

    This document presents the 2004 results of Total Group: consolidated account, special items, number of shares, market environment, adjustment for amortization of Sanofi-Aventis merger-related intangibles, 4. quarter 2004 results (operating and net incomes, cash flow), upstream (results, production, reserves, recent highlights), downstream (results, refinery throughput, recent highlights), chemicals (results, recent highlights), Total's full year 2004 results (operating and net income, cash flow), 2005 sensitivities, Total SA parent company accounts and proposed dividend, adoption of IFRS accounting, summary and outlook, main operating information by segment for the 4. quarter and full year 2004: upstream (combined liquids and gas production by region, liquids production by region, gas production by region), downstream (refined product sales by region, chemicals), Total financial statements: consolidated statement of income, consolidated balance sheet (assets, liabilities and shareholder's equity), consolidated statements of cash flows, business segments information. (J.S.)

  7. Genoptraening efter total knaealloplastik

    DEFF Research Database (Denmark)

    Holm, Bente; Kehlet, Henrik

    2009-01-01

    The short- and long-term benefits of post-discharge physiotherapy regimens after total knee arthroplasty are debatable. A national survey including hospitals in Denmark that perform total knee arthroplasty showed a large variability in indication and regimen for post-knee arthroplasty rehabilitat......The short- and long-term benefits of post-discharge physiotherapy regimens after total knee arthroplasty are debatable. A national survey including hospitals in Denmark that perform total knee arthroplasty showed a large variability in indication and regimen for post-knee arthroplasty...... rehabilitation. Since hospital stay duration has decreased considerably, the need for post-discharge physiotherapy may also have changed. Thus, the indication for and types of rehabilitation programmes need to be studied within the context of fast-track knee arthroplasty....

  8. Genoptraening efter total knaealloplastik

    DEFF Research Database (Denmark)

    Holm, Bente; Kehlet, Henrik

    2009-01-01

    The short- and long-term benefits of post-discharge physiotherapy regimens after total knee arthroplasty are debatable. A national survey including hospitals in Denmark that perform total knee arthroplasty showed a large variability in indication and regimen for post-knee arthroplasty rehabilitat......The short- and long-term benefits of post-discharge physiotherapy regimens after total knee arthroplasty are debatable. A national survey including hospitals in Denmark that perform total knee arthroplasty showed a large variability in indication and regimen for post-knee arthroplasty...... rehabilitation. Since hospital stay duration has decreased considerably, the need for post-discharge physiotherapy may also have changed. Thus, the indication for and types of rehabilitation programmes need to be studied within the context of fast-track knee arthroplasty. Udgivelsesdato: 2009-Feb-23...

  9. Supravaginal eller total hysterektomi?

    DEFF Research Database (Denmark)

    Edvardsen, L; Madsen, E M

    1994-01-01

    There has been a decline in the rate of hysterectomies in Denmark in general over the last thirteen years, together with a rise in the number of supravaginal operations over the last two years. The literature concerning the relative merits of the supravaginal and the total abdominal operation is ...... indicate a reduced frequency of orgasm after the total hysterectomy compared with the supravaginal operation. When there are technical problems peroperatively with an increased urologic risk the supravaginal operation is recommended....

  10. Total lymphoid irradiation

    International Nuclear Information System (INIS)

    Sutherland, D.E.; Ferguson, R.M.; Simmons, R.L.; Kim, T.H.; Slavin, S.; Najarian, J.S.

    1983-01-01

    Total lymphoid irradiation by itself can produce sufficient immunosuppression to prolong the survival of a variety of organ allografts in experimental animals. The degree of prolongation is dose-dependent and is limited by the toxicity that occurs with higher doses. Total lymphoid irradiation is more effective before transplantation than after, but when used after transplantation can be combined with pharmacologic immunosuppression to achieve a positive effect. In some animal models, total lymphoid irradiation induces an environment in which fully allogeneic bone marrow will engraft and induce permanent chimerism in the recipients who are then tolerant to organ allografts from the donor strain. If total lymphoid irradiation is ever to have clinical applicability on a large scale, it would seem that it would have to be under circumstances in which tolerance can be induced. However, in some animal models graft-versus-host disease occurs following bone marrow transplantation, and methods to obviate its occurrence probably will be needed if this approach is to be applied clinically. In recent years, patient and graft survival rates in renal allograft recipients treated with conventional immunosuppression have improved considerably, and thus the impetus to utilize total lymphoid irradiation for its immunosuppressive effect alone is less compelling. The future of total lymphoid irradiation probably lies in devising protocols in which maintenance immunosuppression can be eliminated, or nearly eliminated, altogether. Such protocols are effective in rodents. Whether they can be applied to clinical transplantation remains to be seen

  11. Totally optimal decision rules

    KAUST Repository

    Amin, Talha

    2017-11-22

    Optimality of decision rules (patterns) can be measured in many ways. One of these is referred to as length. Length signifies the number of terms in a decision rule and is optimally minimized. Another, coverage represents the width of a rule’s applicability and generality. As such, it is desirable to maximize coverage. A totally optimal decision rule is a decision rule that has the minimum possible length and the maximum possible coverage. This paper presents a method for determining the presence of totally optimal decision rules for “complete” decision tables (representations of total functions in which different variables can have domains of differing values). Depending on the cardinalities of the domains, we can either guarantee for each tuple of values of the function that totally optimal rules exist for each row of the table (as in the case of total Boolean functions where the cardinalities are equal to 2) or, for each row, we can find a tuple of values of the function for which totally optimal rules do not exist for this row.

  12. Totally optimal decision rules

    KAUST Repository

    Amin, Talha M.; Moshkov, Mikhail

    2017-01-01

    Optimality of decision rules (patterns) can be measured in many ways. One of these is referred to as length. Length signifies the number of terms in a decision rule and is optimally minimized. Another, coverage represents the width of a rule’s applicability and generality. As such, it is desirable to maximize coverage. A totally optimal decision rule is a decision rule that has the minimum possible length and the maximum possible coverage. This paper presents a method for determining the presence of totally optimal decision rules for “complete” decision tables (representations of total functions in which different variables can have domains of differing values). Depending on the cardinalities of the domains, we can either guarantee for each tuple of values of the function that totally optimal rules exist for each row of the table (as in the case of total Boolean functions where the cardinalities are equal to 2) or, for each row, we can find a tuple of values of the function for which totally optimal rules do not exist for this row.

  13. Sin as an Ailment of Soul and Repentance as the Process of Its Healing. The Pastoral Concept of Penitentials as a Way of Dealing with Sin, Repentance, and Forgiveness in the Insular Church of the Sixth to the Eighth Centuries

    Directory of Open Access Journals (Sweden)

    Kursawa Wilhelm

    2017-05-01

    Full Text Available Although the advent of the Kingdom of God in Jesus contains as an intrinsic quality the opportunity for repentance (metanoia as often as required, the Church of the first five-hundred years shows serious difficulties with the opportunity of conversion after a relapse in sinning after baptism. The Church allowed only one chance of repentance. Requirement for the reconciliation were a public confession and the acceptance of severe penances, especially after committing the mortal sin of apostasy, fornication or murder. As severe as this paenitentia canonica appears, its entire conception especially in the eastern part of the Church, the Oriental Church, is a remedial one: sin represents an ailment of the soul, the one, who received the confession, is called upon to meet the confessing person as a spiritual physician or soul-friend. Penance does not mean punishment, but healing like a salutary remedy. Nevertheless, the lack of privacy led to the unwanted practice of postponing repentance and even baptism on the deathbed. An alternative procedure of repentance arose from the sixth century onwards in the Irish Church as well as the Continental Church under the influence of Irish missionaries and the South-West-British and later the English Church (Insular Church. In treatises about repentance, called penitentials, ecclesiastical authorities of the sixth to the eight centuries wrote down regulations, how to deal with the different capital sins and minor trespasses committed by monks, clerics and laypeople. Church-representatives like Finnian, Columbanus, the anonymous author of the Ambrosianum, Cummean and Theodore developed a new conception of repentance that protected privacy and guaranteed a discrete, an affordable as well as a predictable penance, the paenitentia privata. They not only connected to the therapeutic aspect of repentance in the Oriental Church by adopting basic ideas of Basil of Caesarea and John Cassian, they also established an

  14. CONSERVACIÓN POSCOSECHA DE TOMATE DE CÁSCARA (Physalis ixocarpa Brot. ex Horm. CON Y SIN CÁLIZ

    Directory of Open Access Journals (Sweden)

    Oscar Cruz-Álvarez

    2012-01-01

    Full Text Available El objetivo del trabajo fue observar la influencia del cáliz en la vida poscosecha de frutos de tomate de cáscara bajo diferentes temperaturas de almacenamiento (4 y 20 °C con presencia y ausencia del cáliz. El diseño experimental fue completamente al azar con estructura factorial 2 x 2. Se determinaron la tasa de respiración, la producción de etileno, la acidez titulable, la pérdida de peso, los sólidos solubles totales, la vitamina C, la firmeza, el color y la clorofila total. Los tratamientos con presencia del cáliz tuvieron el mayor contenido de clorofila total, con valores que fluctuaron de 0.147 a 0.161 μg.100g, a los 0 y 20 días después de cosecha (ddc, manteniendo la brillantez, cromaticidad y tonalidad del color sin cambios importantes. Los frutos almacenados a temperatura de 4 °C mantuvieron (P ≤ 0.05 el comportamiento de la firmeza y los sólidos solubles, en tanto que los frutos con 20 °C presentaron 5 % de pérdida de peso. Asimismo, el contenido de clorofila fue mayor con valores 0.142 y 0.158 μg 100 g, lo que coincidió con lo observado para los componentes de color. Los cambios manifestados en firmeza, pérdida de peso, contenido de clorofila y color estuvieron relacionados con las temperaturas de almacenamiento, más que con la presencia o ausencia del cáliz.

  15. Total volume versus bouts

    DEFF Research Database (Denmark)

    Chinapaw, Mai; Klakk, Heidi; Møller, Niels Christian

    2018-01-01

    BACKGROUND/OBJECTIVES: Examine the prospective relationship of total volume versus bouts of sedentary behaviour (SB) and moderate-to-vigorous physical activity (MVPA) with cardiometabolic risk in children. In addition, the moderating effects of weight status and MVPA were explored. SUBJECTS....../METHODS: Longitudinal study including 454 primary school children (mean age 10.3 years). Total volume and bouts (i.e. ≥10 min consecutive minutes) of MVPA and SB were assessed by accelerometry in Nov 2009/Jan 2010 (T1) and Aug/Oct 2010 (T2). Triglycerides, total cholesterol/HDL cholesterol ratio (TC:HDLC ratio......, with or without mutual adjustments between MVPA and SB. The moderating effects of weight status and MVPA (for SB only) were examined by adding interaction terms. RESULTS: Children engaged daily in about 60 min of total MVPA and 0-15 min/week in MVPA bouts. Mean total sedentary time was around 7 h/day with over 3...

  16. X-ray diffraction stress analysis of interrupted titanium nitride films: Combining the sin2ψ and crystallite group methods

    International Nuclear Information System (INIS)

    Sinkovits, Theo; Zhao, Yue; O'Brien, Rebecca; Dowey, Steve

    2014-01-01

    Interruptions during film growth have been discussed by researchers to assist in understanding the evolution of stress in physical vapour deposition films. A change in intrinsic stress is directly related to microstructure, hence careful analysis of stress in films can provide valuable structure–stress correlated information. In this study we discuss the use of combining two X-ray diffraction (XRD) stress analysis methods to elucidate the effect of interruptions during growth on the residual stress of TiN films. The sin 2 ψ and crystallite group method (CGM), scanning the (220) peaks from all grains in the film and only (111) oriented crystallites respectively, were used to analyse residual stress in standard and interrupted cathodic arc TiN films 1.5, 3.5 and 6.5 μm thick, grown on high-speed steel substrates. The sin 2 ψ method does not reveal any changes in stress with interruptions, however, measurements using the CGM show increased compressive stress and increased a 0 in the resultant TiN films. A comparison of results from both XRD methods indicates that an increased compressive stress from interruptions could be due to an increased number of defects in (111) oriented grains during the interruptions which would also affect a 0 as evident. In both methods, compressive stresses are found to decrease with increased thickness of films. - Highlights: • Interrupting TiN film growth increases compressive stress in (111) grains. • Increased stress is believed to be caused by defects incorporated into or not annealed out of (111) grains. • A comparison of sin 2 ψ and CGM results reveals differences in stress. • Compressive stress decreases as TiN films increase in thickness from 1.5 μm to 6.5 μm

  17. Medición y predicción de la radiación solar global UV-B bajo cielos claros y sin nubes

    Directory of Open Access Journals (Sweden)

    Jaime Wright Gilmore

    2016-03-01

    Full Text Available Se presentan mediciones experimentales de la radiación solar ultravioleta en el rango B del espectro solar (UV-B y la radiación ultravioleta en el rango total RUV (UV-A+UV-B en días claros y sin nubes en Heredia, Costa Rica. Se utilizó una radiómetro UV-B, que mide la radiación solar en el rango espectral 280-315 nm, y un radiómetro RUV, que mide la radiación solar en el rango espectral 280-385 nm. La dependencia entre entre UV-B y RUV también fue investigada, y se encontró un excelente grado de asociación entre ambas. Además se detalló que UV-B representa solamente un 5,4% de RUV, a pesar de que UV-B es mil veces más potente que UV-A. Los valores de UV-B medidos in situ fueron comparados con los valores predichos por un modelo atmosférico espectral, el cual utiliza como datos de entrada: la hora del día, la latitud, la altitud, el albedo superficial, la distancia Tierra-Sol, la turbiedad atmosférica y el ozono atmosférico. La comparación entre los valores medidos y predichos dio resultados satisfactorios.

  18. Percepción del dolor a la presión en mujeres con y sin dismenorrea

    OpenAIRE

    Cabrera Guerra, Myriam

    2015-01-01

    Introducción. La dismenorrea está considera el trastorno ginecológico más común y una de las principales causas de absentismo escolar y laboral. La prevalencia más alta se produce en la adolescencia y entre los 20 y 25 años, y es menor después de los 30 años. La investigación sobre la percepción dolorosa en mujeres con dismenorrea es escasa y con resultados contradictorios Objetivos. Determinar si existen diferencias en la percepción nociceptiva entre mujeres con y sin dismenorrea, y si ex...

  19. Surface donor states distribution post SiN passivation of AlGaN/GaN heterostructures

    Energy Technology Data Exchange (ETDEWEB)

    Goyal, Nitin, E-mail: nitin@unik.no [Carinthian Tech Research CTR AG, Europastraße 4/1, Technologiepark Villach, A- 9524 Villach/St. Magdalen (Austria); Department of Electronics and Telecommunication, Norwegian University of Science and Technology, Trondheim NO7034 (Norway); Fjeldly, Tor A. [Department of Electronics and Telecommunication, Norwegian University of Science and Technology, Trondheim NO7034 (Norway)

    2014-07-21

    In this paper, we present a physics based analytical model to describe the effect of SiN passivation on two-dimensional electron gas density and surface barrier height in AlGaN/GaN heterostructures. The model is based on an extraction technique to calculate surface donor density and surface donor level at the SiN/AlGaN interface. The model is in good agreement with the experimental results and promises to become a useful tool in advanced design and characterization of GaN based heterostructures.

  20. L’écriture rouge de Sherman Alexie : l’exemple de "The Sin Eaters"

    OpenAIRE

    Sabatier, Diane

    2005-01-01

    If the bodies of Native American individuals seem perpetually tormented and exploited, they constitute means of rebellion when they are transformed into the testimony of a witness – into the body of work of the writer. One can read Sherman Alexie’s collection of short-stories, The Toughest Indian In The World (2001), as scattered bodies regaining shape on paper and forces through his angry red ink. The short-story “The Sin Eaters” constitutes its central nerve with a macabre allegory which li...

  1. Tramas de la violencia de género: sustantivación, metonimias, sinécdoques y preposiciones

    Directory of Open Access Journals (Sweden)

    Elena Casado

    2012-09-01

    Full Text Available Lo que creemos saber sobre la violencia de género (que es una lacra y los maltratadores unos machistas puede estar comprometiendo hoy análisis, diagnósticos e intervenciones. Además “hace género” y afecta al modo y grado en que nos hacemos cargo de la desigualdad. Analizar las sustantivaciones, sinécdoques y metonimias de las tramas de la violencia permite reconstruir relaciones significativas. Porque ¿qué significa la preposición ‘de’ que conecta violencia y género?

  2. Tramas de la violencia de género: sustantivación, metonimias, sinécdoques y preposiciones

    Directory of Open Access Journals (Sweden)

    Elena Casado Aparicio

    2012-01-01

    Full Text Available Lo que creemos saber sobre la violencia de género (que es una lacra y los maltratadores unos machistas puede estar comprometiendo hoy análisis, diagnósticos e intervenciones. Además "hace género" y afecta al modo y grado en que nos hacemos cargo de la desigualdad. Analizar las sustantivaciones, sinécdoques y metonimias de las tramas de la violencia permite reconstruir relaciones significativas. Porque ¿qué significa la preposición 'de' que conecta violencia y género?

  3. Prótesis aórticas sin sutura: revisión de las alternativas actuales

    Directory of Open Access Journals (Sweden)

    Juan J. Otero

    2016-11-01

    Full Text Available Las prótesis sin sutura representan una nueva alternativa en el tratamiento quirúrgico de la estenosis aórtica severa. En el siguiente artículo intentamos resumir las características fundamentales de cada una de ellas y la bibliografía más importante publicada hasta ahora con el fin de hacer una revisión rápida de estas prótesis para poder orientar su uso.

  4. Total versus subtotal hysterectomy

    DEFF Research Database (Denmark)

    Gimbel, Helga; Zobbe, Vibeke; Andersen, Anna Birthe

    2005-01-01

    The aim of this study was to compare total and subtotal abdominal hysterectomy for benign indications, with regard to urinary incontinence, postoperative complications, quality of life (SF-36), constipation, prolapse, satisfaction with sexual life, and pelvic pain at 1-year postoperative. Eighty...... women chose total and 105 women chose subtotal abdominal hysterectomy. No significant differences were found between the 2 operation methods in any of the outcome measures at 12 months. Fourteen women (15%) from the subtotal abdominal hysterectomy group experienced vaginal bleeding and three women had...

  5. Qualità totale e mobilità totale Total Quality and Total Mobility

    Directory of Open Access Journals (Sweden)

    Giuseppe Trieste

    2010-05-01

    Full Text Available FIABA ONLUS (Italian Fund for Elimination of Architectural Barriers was founded in 2000 with the aim of promoting a culture of equal opportunities and, above all, it has as its main goal to involve public and private institutions to create a really accessible and usable environment for everyone. Total accessibility, Total usability and Total mobility are key indicators to define quality of life within cities. A supportive environment that is free of architectural, cultural and psychological barriers allows everyone to live with ease and universality. In fact, people who access to goods and services in the urban context can use to their advantage time and space, so they can do their activities and can maintain relationships that are deemed significant for their social life. The main aim of urban accessibility is to raise the comfort of space for citizens, eliminating all barriers that discriminate people, and prevent from an equality of opportunity. “FIABA FUND - City of ... for the removal of architectural barriers” is an idea of FIABA that has already affected many regions of Italy as Lazio, Lombardy, Campania, Abruzzi and Calabria. It is a National project which provides for opening a bank account in the cities of referring, in which for the first time, all together, individuals and private and public institutions can make a donation to fund initiatives for the removal of architectural barriers within its own territory for a real and effective total accessibility. Last February the fund was launched in Rome with the aim of achieving a Capital without barriers and a Town European model of accessibility and usability. Urban mobility is a prerequisite to access to goods and services, and to organize activities related to daily life. FIABA promotes the concept of sustainable mobility for all, supported by the European Commission’s White Paper. We need a cultural change in management and organization of public means, which might focus on

  6. CSF total protein

    Science.gov (United States)

    CSF total protein is a test to determine the amount of protein in your spinal fluid, also called cerebrospinal fluid (CSF). ... The normal protein range varies from lab to lab, but is typically about 15 to 60 milligrams per deciliter (mg/dL) ...

  7. Total body irradiation

    International Nuclear Information System (INIS)

    Novack, D.H.; Kiley, J.P.

    1987-01-01

    The multitude of papers and conferences in recent years on the use of very large megavoltage radiation fields indicates an increased interest in total body, hemibody, and total nodal radiotherapy for various clinical situations. These include high dose total body irradiation (TBI) to destroy the bone marrow and leukemic cells and provide immunosuppression prior to a bone marrow transplant, high dose total lymphoid irradiation (TLI) prior to bone marrow transplantation in severe aplastic anemia, low dose TBI in the treatment of lymphocytic leukemias or lymphomas, and hemibody irradiation (HBI) in the treatment of advanced multiple myeloma. Although accurate provision of a specific dose and the desired degree of dose homogeneity are two of the physicist's major considerations for all radiotherapy techniques, these tasks are even more demanding for large field radiotherapy. Because most large field radiotherapy is done at an extended distance for complex patient geometries, basic dosimetry data measured at the standard distance (isocenter) must be verified or supplemented. This paper discusses some of the special dosimetric problems of large field radiotherapy, with specific examples given of the dosimetry of the TBI program for bone marrow transplant at the authors' hospital

  8. Total design of participation

    DEFF Research Database (Denmark)

    Munch, Anders V.

    2016-01-01

    The idea of design as an art made not only for the people, but also by the people is an old dream going back at least to William Morris. It is, however, reappearing vigoriously in many kinds of design activism and grows out of the visions of a Total Design of society. The ideas of participation b...

  9. Total Quality Management Simplified.

    Science.gov (United States)

    Arias, Pam

    1995-01-01

    Maintains that Total Quality Management (TQM) is one method that helps to monitor and improve the quality of child care. Lists four steps for a child-care center to design and implement its own TQM program. Suggests that quality assurance in child-care settings is an ongoing process, and that TQM programs help in providing consistent, high-quality…

  10. Total Quality Management Seminar.

    Science.gov (United States)

    Massachusetts Career Development Inst., Springfield.

    This booklet is one of six texts from a workplace literacy curriculum designed to assist learners in facing the increased demands of the workplace. The booklet contains seven sections that cover the following topics: (1) meaning of total quality management (TQM); (2) the customer; (3) the organization's culture; (4) comparison of management…

  11. Total photon absorption

    International Nuclear Information System (INIS)

    Carlos, P.

    1985-01-01

    Experimental methods using real photon beams for measurements of total photonuclear absorption cross section σ(Tot : E/sub γ/) are recalled. Most recent σ(Tot : E/sub γ/)results for complex nuclei and in the nucleon resonance region are presented

  12. Total 2004 annual report

    International Nuclear Information System (INIS)

    2004-01-01

    This annual report of the Group Total brings information and economic data on the following topics, for the year 2004: the corporate governance, the corporate social responsibility, the shareholder notebook, the management report, the activities, the upstream (exploration and production) and downstream (refining and marketing) operating, chemicals and other matters. (A.L.B.)

  13. Total Water Management - Report

    Science.gov (United States)

    There is a growing need for urban water managers to take a more holistic view of their water resource systems as population growth, urbanization, and current operations put different stresses on the environment and urban infrastructure. Total Water Management (TWM) is an approac...

  14. Survey: Did the TFP Growth Rate in Japan Decline in the 1990s?(in Japanese)

    OpenAIRE

    INUI Tomohiko; KWON Hyeog Ug

    2004-01-01

    This paper surveys the body of research grounded on a basic question "Did the total factor productivity (TFP) growth rate in Japan decline in the 1990s?" In addition, using industry-level data of the Japan Industrial Productivity Database (JIP database) we estimate the mark-ups and the degree of returns to scale and then re-estimate TFP growth rates. Most of studies reviewed in this paper show a decline in TFP growth in the 1990s at the macro-level and the industry-level. There are some studi...

  15. Tunable Luminescence of CeAl11O18 Based Phosphors by Replacement of (AlO)+ by (SiN)+ and Co-Doping with Eu

    NARCIS (Netherlands)

    Yin, L.J.; Chen, G.Z; Wang, C.; Xu, X.; Hao, L.Y.; Hintzen, H.T.J.M.

    2014-01-01

    A series of Si-N or Eu-Li doped CeAl11O18 and CeAl12O18N phosphors are prepared by solid–state reaction. Their structure and luminescence are researched carefully. Si-N doping with the concentration less than 8% can be successfully dissolved into CeAl11O18 crystal lattice and doesn't change the

  16. Pájaros enjaulados: homosexualidad y prisión en Hombres sin mujer

    Directory of Open Access Journals (Sweden)

    Gallardo Saborido, Emilio José

    2010-06-01

    Full Text Available This article aims to focus on the interaction between homosexuality and prison in the novel by the Cuban writer Carlos Montenegro, titled Hombres sin mujer (1938. From a sociological approach to literature, we structurally analyze the homosexual notions and practices in a particular Cuban jail. In this regard, we specifically explain their components and the creation of self-explicative categories or ethnocategories. Furthermore, the order which constitutes these elements and the conflicts that dynamize them are studied. Finally, the article concludes considering the notion of homosexuality in prison as a tragedy; an idea that closes the novel.

    Este artículo se centra en la interacción entre homosexualidad y prisión en la novela del cubano Carlos Montenegro titulada “Hombres sin mujer” (1938. A partir de una aproximación sociológica al hecho literario, se analizan estructuralmente las nociones y prácticas homosexuales carcelarias, teniendo en cuenta especialmente sus componentes y la creación de categorías auto-explicativas o etnocategorías, el orden en el que se constituyen estos elementos y los conflictos que los animan. Finalmente, se concluye considerando la noción de homosexualidad carcelaria como tragedia con la que se cierra la obra.

  17. Efecto sinérgico del aceite esencial de Origanum vulgare a la Gentamicina en cultivos de Escherichia coli.

    Directory of Open Access Journals (Sweden)

    Luis Chávez Torres

    2008-01-01

    Full Text Available Objetivo: El presente trabajo tuvo como propósito determinar el efecto sinérgico antibacteriano entre el aceite esencial de Origanum vulgare y la Gentamicina en aislados de Escherichia coli. Diseño: Estudio experimental Lugar: Centro Latinoamericano de Enseñanza e Investigación en Bacteriología Alimentaria (CLEIBA Participantes: Placas Petri conteniendo E. Coli ATCC 25922, aceite esencial de orégano y Gentamicina. Intervenciones: Se aplicó el método de Kirby Bauer (discos de difusión en 20 placas Petri. Se aisló la cepa Escherichia coli ATCC 25922. El grupo Experimental fue tratado con discos de papel filtro, embebidos con Gentamicina y aceite esencial de orégano al 75%; mientras que el grupo Control, con discos de Gentamicina sola. Se realizó la medición de los halos y se registraron los datos. Principales medidas de resultados: Se evaluó el diámetro de los halos de inhibición Resultados: Los halos de inhibición del grupo Experimental resultaron 22,375 mm., mayores que los del grupo Control (20,75 mm. La prueba T determinó que la diferencia era estadísticamente significativa, p = 0,001 (p < 0,05. Conclusiones: Existe un efecto sinérgico antibacteriano in vitro entre el aceite esencial de Origanum vulgare y la gentamicina en E. coli.

  18. Uncertainty, God, and scrupulosity: Uncertainty salience and priming God concepts interact to cause greater fears of sin.

    Science.gov (United States)

    Fergus, Thomas A; Rowatt, Wade C

    2015-03-01

    Difficulties tolerating uncertainty are considered central to scrupulosity, a moral/religious presentation of obsessive-compulsive disorder (OCD). We examined whether uncertainty salience (i.e., exposure to a state of uncertainty) caused fears of sin and fears of God, as well as whether priming God concepts affected the impact of uncertainty salience on those fears. An internet sample of community adults (N = 120) who endorsed holding a belief in God or a higher power were randomly assigned to an experimental manipulation of (1) salience (uncertainty or insecurity) and (2) prime (God concepts or neutral). As predicted, participants who received the uncertainty salience and God concept priming reported the greatest fears of sin. There were no mean-level differences in the other conditions. The effect was not attributable to religiosity and the manipulations did not cause negative affect. We used a nonclinical sample recruited from the internet. These results support cognitive-behavioral models suggesting that religious uncertainty is important to scrupulosity. Implications of these results for future research are discussed. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. S-I-N tunneling spectroscopy of MgB2 superconductor: evidence of two superconducting energy gaps

    International Nuclear Information System (INIS)

    Sen, Shashwati; Aswal, D.K.; Singh, Ajay; Gadkari, S.C.; Shah, K.; Gupta, S.K.; Sahni, V.C.

    2002-01-01

    The tunneling spectra of polycrystalline MgB 2 , have been recorded, at different temperatures between 29 K and T c , using planar superconductor- insulating-normal (S-I-N) tunneling spectroscopy. The planar S-I-N tunnel junctions have been fabricated by thermally evaporating Ag electrodes on MgB 2 surface. The naive layer, which forms at the surface of MgB 2 , due to atmospheric degradation, was employed as an insulating layer between Ag electrodes and MgB 2 . We have found presence of two clear superconducting energy gaps in MgB 2 . The magnitudes of these gaps at 29.5 K are 1.8 and 5.9 MeV, respectively. In the vicinity of T c , while larger energy gap obeyed BCS temperature dependence, the smaller energy gap deviated from BCS dependence. All the spectra exhibited zero-bias conductance, which decreased linearly with temperature and vanished at T c . (author)

  20. Valores percibidos en la publicidad de alimentos por jóvenes con y sin trastornos de la conducta alimentaria

    Directory of Open Access Journals (Sweden)

    Lluís Mas-Manchón

    2015-01-01

    Full Text Available La publicidad utiliza imágenes corporales fuertemente estereotipadas para promocionar cánones físicos y conductas alimentarias no saludables asociadas a productos de alimentación dirigidos sobre todo a jóvenes. El objetivo de este estudio, realizado en Barcelona (España durante el mes de mayo de 2013, es testear la percepción de 25 valores en siete spots televisivos de alimentación (con y sin estrategias de imagen corporal en 139 jóvenes con y sin trastornos de la conducta alimentaria (TCA. Los resultados muestran que solo el grupo de jóvenes con TCA considera que los spots con una estrategia comercial basada en la imagen corporal influyen muy negativamente en valores como salud, bienestar, familia y esfuerzo. En cambio, se ha observado una gran coincidencia entre los dos grupos cuando se evalúa el resto de los spots. Estos resultados señalan que los jóvenes universitarios españoles de hoy han aceptado como normal un canon de belleza basado en el orden social y económico, mientras que los jóvenes en tratamiento por desórdenes alimenticios sí han aprendido a decodificar este tipo de mensajes.

  1. Development and preliminary validation of a measure of social inclusion for use in people with mental health problems: the SInQUE.

    Science.gov (United States)

    Mezey, Gillian; White, Sarah; Thachil, Ajoy; Berg, Rachel; Kallumparam, Sen; Nasiruddin, Omar; Wright, Christine; Killaspy, Helen

    2013-08-01

    Social exclusion can be both a cause and a consequence of mental health problems. Socially inclusive practice by mental health professionals can mitigate against the stigmatizing and excluding effects of severe mental illness. To develop and test the validity of a measure of social inclusion for individuals with severe mental illness - the Social Inclusion Questionnaire User Experience (SInQUE). The domains of the SInQUE were chosen to reflect the domains of social inclusion identified in the Poverty and Social Exclusion Survey. Patients with severe mental illness were recruited from rehabilitation, general and forensic psychiatric services and were asked to complete the questionnaire in an individual interview with a researcher. Sixty six patients with schizophrenia and schizoaffective disorder completed the SInQUE, alongside measures of psychiatric symptoms, needs and quality of life, to assess its acceptability, and concurrent and construct (convergent and discriminant) validity. The SInQUE took 45 minutes to complete and was found to have good concurrent and discriminant validity. Convergent validity was established for two domains: social integration and productivity. Preliminary findings suggest that the SInQUE may be a useful tool for assessing and monitoring social inclusion in individuals with severe mental illness. It has construct and concurrent validity with measures of unmet need and quality of life in this group. Further testing of the reliability of the SInQUE on a larger population is indicated.

  2. Total 2003 Results

    International Nuclear Information System (INIS)

    2003-01-01

    This document presents the 2003 results of Total Group: consolidated account, special items, number of shares, market environment, 4. quarter 2003 results, full year 2003 results, upstream (key figures, proved reserves), downstream key figures, chemicals key figures, parent company accounts and proposed dividends, 2004 sensitivities, summary and outlook, operating information by segment for the 4. quarter and full year 2003: upstream (combined liquids and gas production by region, liquids production by region, gas production by region), downstream (refinery throughput by region, refined product sales by region, chemicals), impact of allocating contribution of Cepsa to net operating income by business segment: equity in income (loss) and affiliates and other items, Total financial statements: consolidated statement of income, consolidated balance sheet (assets, liabilities and shareholder's equity), consolidated statements of cash flows, business segments information. (J.S.)

  3. TOTAL PERFORMANCE SCORECARD

    Directory of Open Access Journals (Sweden)

    Anca ȘERBAN

    2013-06-01

    Full Text Available The purpose of this paper is to present the evolution of the Balanced Scorecard from a measurement instrument to a strategic performance management tool and to highlight the advantages of implementing the Total Performance Scorecard, especially for Human Resource Management. The study has been accomplished using the methodology of bibliographic study and various secondary sources. Implementing the classical Balanced Scorecard indicated over the years, repeatedly failure. It can be indicated that the crucial level is determined by the learning and growth perspective. It has been developed from a human perspective, which focused on staff satisfaction, innovation perspective with focus on future developments. Integrating the Total Performance Scorecard in an overall framework assures the company’s success, by keeping track of the individual goals, the company’s objectives and strategic directions. Like this, individual identity can be linked to corporate brand, individual aspirations to business goals and individual learning objectives to needed organizational capabilities.

  4. Totally parallel multilevel algorithms

    Science.gov (United States)

    Frederickson, Paul O.

    1988-01-01

    Four totally parallel algorithms for the solution of a sparse linear system have common characteristics which become quite apparent when they are implemented on a highly parallel hypercube such as the CM2. These four algorithms are Parallel Superconvergent Multigrid (PSMG) of Frederickson and McBryan, Robust Multigrid (RMG) of Hackbusch, the FFT based Spectral Algorithm, and Parallel Cyclic Reduction. In fact, all four can be formulated as particular cases of the same totally parallel multilevel algorithm, which are referred to as TPMA. In certain cases the spectral radius of TPMA is zero, and it is recognized to be a direct algorithm. In many other cases the spectral radius, although not zero, is small enough that a single iteration per timestep keeps the local error within the required tolerance.

  5. Total space in resolution

    Czech Academy of Sciences Publication Activity Database

    Bonacina, I.; Galesi, N.; Thapen, Neil

    2016-01-01

    Roč. 45, č. 5 (2016), s. 1894-1909 ISSN 0097-5397 R&D Projects: GA ČR GBP202/12/G061 EU Projects: European Commission(XE) 339691 - FEALORA Institutional support: RVO:67985840 Keywords : total space * resolution random CNFs * proof complexity Subject RIV: BA - General Mathematics Impact factor: 1.433, year: 2016 http://epubs.siam.org/doi/10.1137/15M1023269

  6. MFTF TOTAL benchmark

    International Nuclear Information System (INIS)

    Choy, J.H.

    1979-06-01

    A benchmark of the TOTAL data base management system as applied to the Mirror Fusion Test Facility (MFTF) data base was implemented and run in February and March of 1979. The benchmark was run on an Interdata 8/32 and involved the following tasks: (1) data base design, (2) data base generation, (3) data base load, and (4) develop and implement programs to simulate MFTF usage of the data base

  7. Total - annual report 2005

    International Nuclear Information System (INIS)

    2006-01-01

    This annual report presents the activities and results of TOTAL S.A., french society on oil and gas. It deals with statistics, the managers, key information on financial data and risk factors, information on the Company, unresolved Staff Comments, employees, major Shareholders, consolidated statements, markets, security, financial risks, defaults dividend arrearages and delinquencies, controls and procedures, code of ethics and financial statements. (A.L.B.)

  8. Total Absorption Spectroscopy

    International Nuclear Information System (INIS)

    Rubio, B.; Gelletly, W.

    2007-01-01

    The problem of determining the distribution of beta decay strength (B(GT)) as a function of excitation energy in the daughter nucleus is discussed. Total Absorption Spectroscopy is shown to provide a way of determining the B(GT) precisely. A brief history of such measurements and a discussion of the advantages and disadvantages of this technique, is followed by examples of two recent studies using the technique. (authors)

  9. SIN TIERRAS NI LETRAS... HISTORIA DE LA EDUCACION MAPUCHE EN EL PERIODO REDUCCIONAL (1880-1930)

    OpenAIRE

    CANO, DANIEL

    2011-01-01

    Este es un estudio que analiza históricamente la educación entregada a los mapuches durante los años reduccionales. Dicho periodo ha sido determinado por la historiografía nacional como el tiempo que transcurrió desde la entrega del primer título de merced en 1884 –un año tras el término de la ocupación de la Araucanía- hasta 1929, cuando se concedió el último de aquellos títulos. Nuestro objetivo principal fue conocer con certeza el número total de niños mapuches que asistieron a la escuela ...

  10. Voltage pre-regulator without insulation with high efficiency; Pre-regulador de tension sin aislamiento con alta eficiencia

    Energy Technology Data Exchange (ETDEWEB)

    Lopez Ramos, Octaviano

    2003-04-15

    strokes it is illustrated that the results obtained in the proposed topology are satisfactory because it succeeds in maintaining a high efficiency and a high power factor. [Spanish] Actualmente existe una problematica por el uso inadecuado e ineficiente de la energia electrica en los sistemas de alimentacion, esta problematica se va complicando aun mas con el paso del tiempo, debido a la proliferacion de equipos electronicos que no incorporan alguna solucion para dicha problematica. Esto ha ocasionado una tendencia hacia el desarrollo de sistemas que procesen con mayor eficiencia ({eta}) la energia electrica. Ademas para hacer un buen uso de la energia, se les disena para que puedan corregir el factor de potencia (FP) y por lo tanto reducen la contaminacion de armonicos en la red; los cuales provocan fallas o destruccion en otros equipos electronicos. Adicionalmente se les puede disenar para obtener una buena respuesta dinamica, lo cual asegura que podran contrarrestar eficientemente cambios de carga. La caracteristica no lineal que esta presente en todas las fuentes de alimentacion, que basan su entrada en una etapa de rectificacion y filtrado, provocan un bajo factor de potencia (FP) y una alta distorsion armonica total (THD). El factor es contaminar la red electrica, lo cual puede provocar fallas o descomposturas de otros equipos. Desde hace aproximadamente 15 anos la preocupacion por resolver este problema de uso inadecuado de la energia ha tomado importancia, desarrollando convertidores que corrigen el FP (pre-regulador) y que tradicionalmente se conectan en cascada con la tipica etapa de conversion de corriente directa a corriente directa (CD-CD) usada para regular la tension; esta solucion tiene una baja eficiencia ({eta}) y alto costo, por el exceso de componentes conectados en cascada. Sin embargo la respuesta dinamica (RD) es adecuada ya que se cuenta con etapas separadas para la correccion del FP y la regulacion. A partir de una revision del estado del arte, en

  11. Total Synthesis of Hyperforin.

    Science.gov (United States)

    Ting, Chi P; Maimone, Thomas J

    2015-08-26

    A 10-step total synthesis of the polycyclic polyprenylated acylphloroglucinol (PPAP) natural product hyperforin from 2-methylcyclopent-2-en-1-one is reported. This route was enabled by a diketene annulation reaction and an oxidative ring expansion strategy designed to complement the presumed biosynthesis of this complex meroterpene. The described work enables the preparation of a highly substituted bicyclo[3.3.1]nonane-1,3,5-trione motif in only six steps and thus serves as a platform for the construction of easily synthesized, highly diverse PPAPs modifiable at every position.

  12. Total quality is people

    International Nuclear Information System (INIS)

    Vogel, C.E.

    1991-01-01

    Confronted by changing market conditions and increased global competition, in 1983 the Commercial Nuclear Fuel Division (CNFD) of Westinghouse Electric embarked on an ambitious plan to make total quality the centerpiece of its long-term business strategy. Five years later, the division's efforts in making continuous quality improvement a way of life among its more than 2,000 employees gained national recognition when it was named a charter recipient of the Malcolm Baldridge National Quality Award. What CNFD achieved during the 1980s was a cultural transformation, characterized by an empowered work force committed to a common vision. The company's quality program development strategy is described

  13. Total quality accounting

    Directory of Open Access Journals (Sweden)

    Andrijašević Maja

    2008-01-01

    Full Text Available The focus of competitive "battle" shifted from the price towards non-price instruments, above all, towards quality that became the key variable for profitability increase and achievement of better comparative position of a company. Under such conditions, management of a company, which, according to the established and certified system of total quality, strives towards achieving of a better market position, faces the problem of quality cost measurement and determination. Management, above all, cost accounting can help in solving of this problem, but the question is how much of its potential is being used for that purpose.

  14. Total_Aktion

    DEFF Research Database (Denmark)

    Søndergaard, Morten

    2008-01-01

    digitale medier er registreringen og muligheden for at opbevare og håndtere digital data uden begrænsninger. Oplevelse, registrering og bevaring knyttes sammen i en ny museal virkelighed, hvor samlingens særlige dokumentariske karakter og fokus, som er unikt for Museet for Samtidskunst, er i centrum...... at mikse deres personlige drinks. TOTAL_AKTION viser Hørbar#3, som er en videreudvikling af den første version. METASYN af Carl Emil Carlsen: Metadata er centralt for Carl Emil Carlsens projekt, der betragter museets samling som et ”univers” af værker (analoge og digitale), beskrivelser og relationer. I...

  15. Total Logistic Plant Solutions

    Directory of Open Access Journals (Sweden)

    Dusan Dorcak

    2016-02-01

    Full Text Available The Total Logistics Plant Solutions, plant logistics system - TLPS, based on the philosophy of advanced control processes enables complex coordination of business processes and flows and the management and scheduling of production in the appropriate production plans and planning periods. Main attributes of TLPS is to create a comprehensive, multi-level, enterprise logistics information system, with a certain degree of intelligence, which accepts the latest science and research results in the field of production technology and logistics. Logistic model of company understands as a system of mutually transforming flows of materials, energy, information, finance, which is realized by chain activities and operations

  16. Total Factbook 2003

    International Nuclear Information System (INIS)

    2003-01-01

    This report presents the activities and results of the Group Total-Fina-Elf for the year 2003. It brings information and economic data on the following topics: the corporate and business; the upstream activities with the reserves, the costs, standardized measure and changes of discounted future net cash flow,oil and gas acreage, drilling, liquefied natural gas, pipelines; downstream activities with refining and marketing maps, refinery, petroleum products, sales, retail gasoline outlets; chemicals with sales and operating income by sector, major applications, base chemicals and polymers, intermediates and performance polymers. (A.L.B.)

  17. Total 2004 fact book

    International Nuclear Information System (INIS)

    2004-01-01

    This report presents the activities and results of the Group Total-Fina-Elf for the year 2004. It brings information and economic data on the following topics: the corporate and business; the upstream activities with the reserves, the costs, standardized measure and changes of discounted future net cash flow,oil and gas acreage, drilling, liquefied natural gas, pipelines; downstream activities with refining and marketing maps, refinery, petroleum products, sales, retail gasoline outlets; chemicals with sales and operating income by sector, major applications, base chemicals and polymers, intermediates and performance polymers. (A.L.B.)

  18. TOTAL annual report 2003

    International Nuclear Information System (INIS)

    2004-01-01

    This 2003 annual report of the Group Total provides economical results and information of the society on the following topics: keys data, the corporate governance (Directors charter, board of directors, audit committee, nomination and remuneration committee, internal control procedures, compensation of directors and executive officers), the corporate social responsibility (environmental stewardship, the future of energy management, the safety enhancement, the human resources, ethics and local development), the investor relations, the management report, the upstream exploration and production, the downstream refining, marketing, trading and shipping, the chemicals and financial and legal information. (A.L.B.)

  19. Total knee arthroplasty

    DEFF Research Database (Denmark)

    Schrøder, Henrik M.; Petersen, Michael M.

    2016-01-01

    Total knee arthroplasty (TKA) is a successful treatment of the osteoarthritic knee, which has increased dramatically over the last 30 years. The indication is a painful osteoarthritic knee with relevant radiographic findings and failure of conservative measures like painkillers and exercise...... surgeon seems to positively influence the rate of surgical complications and implant survival. The painful TKA knee should be thoroughly evaluated, but not revised except if a relevant indication can be established. The most frequent indications for revision are: aseptic loosening, instability, infection...

  20. Test de Rorscharch: respuestas diferenciales entre pacientes con y sin intento suicida

    Directory of Open Access Journals (Sweden)

    Alejandro Cuadra-Peralta

    2009-12-01

    Full Text Available Este estudio tuvo como objetivo identificar respuestas diferenciales entre grupos de No-pacientes, pacientes diagnosticados con Depresión, pacientes diagnosticados con Trastorno de Personalidad y con Depresión y pacientes con intento suicida a través de los indicadores de la Escala de Potencial suicida, propuesto por Passalacqua, Herrera y Orcoyen (1997. La muestra total fue de 70 sujetos de sexo femenino, con grupos de aproximadamente 18 personas cada uno. Se encontró diferencia significativa en seis indicadores entre los cuatro grupos y en diez indicadores entre los pacientes con intento suicida y los demás participantes. Con estos indicadores se realizó un análisis discriminante, encontrándose una alta capacidad para diferenciar los diferentes subgrupos, en especial a grupo de pacientes con intento suicida y el resto de las personas. Se entrega una formula para calcular la probabilidad de pertenencia al grupo de intento de suicidio.

  1. Inversor monofásico de alta eficiencia sin transformador para aplicaciones fotovoltaicas

    Directory of Open Access Journals (Sweden)

    Vázquez-Guzmán Gerardo

    2015-03-01

    Full Text Available Photovoltaic (PV inverters have a very important role in the energy market, therefore they must possess excellent characteristics regarding cost and reliability. The PV structure most often used in the conversion stage of solar energy system includes a Low Frequency Transformer (LFT which provides galvanic isolation, but on the other hand reduces the overall efficiency and increases the total size and cost of the system. An alternative to reduce the size of the system and the losses, is to use a High Frequency Transformer (HFT, the problem in this case is that additional power stages must be included in the system. The additional stages increase the power losses in the conversion process, as a consequence the efficiency of the system is reduced. Therefore the tendency is to remove the transformer in order to increase the efficiency and reduce the cost. A security problem regarding common mode currents arise when the LFT or HFT is omitted. In this paper an inverter topology to deal with the problem of the common mode currents is proposed. Numerical results are performed in order to prove the performance of the topology regarding efficiency and Common Mode Voltage (CMV issues

  2. TOTAL user manual

    Science.gov (United States)

    Johnson, Sally C.; Boerschlein, David P.

    1994-01-01

    Semi-Markov models can be used to analyze the reliability of virtually any fault-tolerant system. However, the process of delineating all of the states and transitions in the model of a complex system can be devastatingly tedious and error-prone. Even with tools such as the Abstract Semi-Markov Specification Interface to the SURE Tool (ASSIST), the user must describe a system by specifying the rules governing the behavior of the system in order to generate the model. With the Table Oriented Translator to the ASSIST Language (TOTAL), the user can specify the components of a typical system and their attributes in the form of a table. The conditions that lead to system failure are also listed in a tabular form. The user can also abstractly specify dependencies with causes and effects. The level of information required is appropriate for system designers with little or no background in the details of reliability calculations. A menu-driven interface guides the user through the system description process, and the program updates the tables as new information is entered. The TOTAL program automatically generates an ASSIST input description to match the system description.

  3. Gas diffusion ultrabarriers on polymer substrates using Al2O3 atomic layer deposition and SiN plasma-enhanced chemical vapor deposition

    International Nuclear Information System (INIS)

    Carcia, P. F.; McLean, R. S.; Groner, M. D.; Dameron, A. A.; George, S. M.

    2009-01-01

    Thin films grown by Al 2 O 3 atomic layer deposition (ALD) and SiN plasma-enhanced chemical vapor deposition (PECVD) have been tested as gas diffusion barriers either individually or as bilayers on polymer substrates. Single films of Al 2 O 3 ALD with thicknesses of ≥10 nm had a water vapor transmission rate (WVTR) of ≤5x10 -5 g/m 2 day at 38 deg. C/85% relative humidity (RH), as measured by the Ca test. This WVTR value was limited by H 2 O permeability through the epoxy seal, as determined by the Ca test for the glass lid control. In comparison, SiN PECVD films with a thickness of 100 nm had a WVTR of ∼7x10 -3 g/m 2 day at 38 deg. C/85% RH. Significant improvements resulted when the SiN PECVD film was coated with an Al 2 O 3 ALD film. An Al 2 O 3 ALD film with a thickness of only 5 nm on a SiN PECVD film with a thickness of 100 nm reduced the WVTR from ∼7x10 -3 to ≤5x10 -5 g/m 2 day at 38 deg. C/85% RH. The reduction in the permeability for Al 2 O 3 ALD on the SiN PECVD films was attributed to either Al 2 O 3 ALD sealing defects in the SiN PECVD film or improved nucleation of Al 2 O 3 ALD on SiN.

  4. Efectos a largo plazo de los síntomas depresivos en una tarea de memoria de trabajo con y sin interferencia atencional

    Directory of Open Access Journals (Sweden)

    Silvia Botelho de Oliveira

    2015-01-01

    Full Text Available La neurobiología de la depresión involucra cambios estructurales del sistema nervioso relacionados con procesos cognitivos como la memoria y la atención. El objetivo del presente estudio fue evaluar el efecto a largo plazo de la sintomatología depresiva (SD en una tarea de memoria de trabajo visual con y sin interferencia atencional en estudiantes universitarios. Se utilizó un diseño factorial de 2 × 2 en el cual las variables independientes fueron la condición clínica (con SD y sin SD y la versión del Memonum (con o sin interferencia de color. Memonum es un software para evaluar memoria de trabajo por medio de la retención de dígitos directos, en dos versiones: una blanco-negro (sin interferencia y otra con un distractor atencional de color (con interferencia. Para la evaluación de la SD, 76 universitarios respondieron al CES-D, luego se les aplicó aleatoriamente una u otra versión de la prueba Memonum (con o sin interferencia de color, 2 semanas después de la detección de síntomas. De manera general, la SD no alteró a largo plazo el desempeño de los participantes en tareas de memoria de trabajo visual con o sin interferencia atencional. Sin embargo, se pudo establecer que la utilización de las estrategias para la ejecución de la tarea mnemónica dependió de la condición clínica, y la agrupación fue la menos usada por los participantes con SD.

  5. Total process surveillance: (TOPS)

    International Nuclear Information System (INIS)

    Millar, J.H.P.

    1992-01-01

    A Total Process Surveillance system is under development which can provide, in real-time, additional process information from a limited number of raw measurement signals. This is achieved by using a robust model based observer to generate estimates of the process' internal states. The observer utilises the analytical reduncancy among a diverse range of transducers and can thus accommodate off-normal conditions which lead to transducer loss or damage. The modular hierarchical structure of the system enables the maximum amount of information to be assimilated from the available instrument signals no matter how diverse. This structure also constitutes a data reduction path thus reducing operator cognitive overload from a large number of varying, and possibly contradictory, raw plant signals. (orig.)

  6. Total and EDF invest

    International Nuclear Information System (INIS)

    Signoret, St.

    2008-01-01

    So as to prepare the future of their industrial sector,the Total company plans to invest (14 billion Euros in 2008) to increase its production capacities and strengthen in of other activities as the liquefied natural gas and the renewable energies; EDF plans to inject 35 billion Euros over three years to multiply the new projects of power plants (wind turbines, coal in Germany, gas in Great Britain and nuclear power in Flamanville). EDF wants to exploit its knowledge of leader to run more than ten E.P.R.(European pressurized water reactor) in the world before 2020, projects are in examination with China, Great Britain, South Africa and United States. (N.C.)

  7. Total quality at source

    International Nuclear Information System (INIS)

    Chiandone, A.C.

    1990-01-01

    The Total Quality at Source philosophy is based on optimizing the effectiveness of people in achieving ZERO-DEFECT results. In this paper a philosophy of what, I have come to perceive, it takes to get people to perform to the very best of their abilities and thereby achieve the best results they can, is presented. In the examples I shall describe I have played an instrumental role since it has become my belief that any job can always be done better provided that the people doing it can themselves become convinced that they can do better. Clearly there are many ideas on how to do this. The philosophy that I am presenting in this paper is based on my own experience, where I have both participated and observed it being applied; its effectiveness may be judged by the results. (author)

  8. Total ankle joint replacement.

    Science.gov (United States)

    2016-02-01

    Ankle arthritis results in a stiff and painful ankle and can be a major cause of disability. For people with end-stage ankle arthritis, arthrodesis (ankle fusion) is effective at reducing pain in the shorter term, but results in a fixed joint, and over time the loss of mobility places stress on other joints in the foot that may lead to arthritis, pain and dysfunction. Another option is to perform a total ankle joint replacement, with the aim of giving the patient a mobile and pain-free ankle. In this article we review the efficacy of this procedure, including how it compares to ankle arthrodesis, and consider the indications and complications. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  9. ¿Ciudad sin ciudadanos? Fragmentación, segregación y temor en Santiago

    Directory of Open Access Journals (Sweden)

    Lucía Dammert

    2004-12-01

    Full Text Available La imagen de la ciudad como espacio de interacción y celebración de las diferencias está siendo amenazada en Santiago. Visiones alternativas la muestran como espacio de conflicto, desorden e inseguridad, donde la diferencia se convierte en un elemento peligroso que requiere ser excluido o segregado. De esta manera se desarrolla una ciudad sin ciudadanos, es decir, una no-ciudad, que sirve como espacio de movimiento pero no de interacción. El objetivo de este artículo es empezar a analizar esta problemática desde uno de sus elementos: la sensación de inseguridad. El resultado plantea interrogantes sobre la ciudad que se está construyendo y sus posibles consecuencias.

  10. Herpes zóster oftálmico en paciente pediátrico sin inmunocompromiso

    Directory of Open Access Journals (Sweden)

    Diego Zamora-de la Cruz

    2015-04-01

    La paciente evolucionó favorablemente, sin presentar secuelas significativas. Se mantuvo vigilada a la paciente durante los 3 meses posteriores al cuadro. El diagnóstico de esta entidad es principalmente clínico; se sabe que uno de los factores de riesgo más importantes en este grupo de edad no es el inmunocompromiso, sino la infección por varicela zóster durante el primer año de vida. Es primordial realizar siempre una evaluación exhaustiva en los pacientes con estas características por las secuelas a largo plazo y el riesgo de ambliopía por deprivación en caso de leucomas corneales residuales. El curso clínico del herpes zóster oftálmico en niños inmunocompetentes es benigno si se trata oportunamente con aciclovir.

  11. ¿Es posible construir una escuela sin exclusiones? Is it possible to build a school without exclusion?

    Directory of Open Access Journals (Sweden)

    Miguel López Melero

    2008-04-01

    Full Text Available Este artículo plantea, fundamentalmente, que no se debe confundir integración educativa con escuela inclusiva y que, probablemente, esta confusión ha originado interpretaciones dispares que está originando una serie de barreras para la presencia, aprendizaje y participación de las personas y culturas diferentes en el aula. Se analizan solo las barreras didácticas y se propone como se pueden salvar las mismas para construir una escuela sin exclusiones.The main idea in this article is that we must not confuse the concept of "educational integration" with "inclusive schooling". Probably, such confusion has generated different interpretations of the above concepts resulting in barriers in learning and participation in the classroom for those who are different or who come from diverse cultural backgrounds. The article analyses mainly barriers in didactics and suggests how to overcome them in order to construct a school without exclusion.

  12. La comprensión verbal y la lectura en niños con y sin retraso lector

    OpenAIRE

    Luisa Fernanda Bohórquez Montoya; María Alejandra Cabal Álvarez; María Cristina Quijano Martínez

    2014-01-01

    Describir diferencias entre el desempeño en tareas de lectura y de comprensión verbal en niños con y sin retraso lector, así como la relación entre ambos tipos de desempeños. Método. Se utilizaron tareas de lectura de la Evaluación neuropsicológica infantil (ENI) y el Índice de Comprensión Verbal (ICV) de la escala de inteligencia Wechsler (WISC-IV) para niños. Los participantes fueron 40 niños de ambos sexos, entre 7 y 9 años de edad, quienes cursaban entre 2° y 4° grado de primaria en un co...

  13. La comprensión verbal y la lectura en niños con y sin retraso lector

    OpenAIRE

    Bohórquez Montoya, Luisa Fernanda; Cabal álvarez, María Alejandra; Quijano Martínez, María Cristina

    2014-01-01

    Objetivo. Describir diferencias entre el desempeño en tareas de lectura y de comprensión verbal en niños con y sin retraso lector, así como la relación entre ambos tipos de desempeños. Método. Se utilizaron tareas de lectura de la Evaluación neuropsicológica infantil (ENI) y el índice de Comprensión Verbal (ICV) de la escala de inteligencia Wechsler (WISC-IV) para niños. Los participantes fueron 40 niños de ambos sexos, entre 7 y 9 años de edad, quienes cursaban entre 2° y 4° grado de primari...

  14. PERSISTENCIA DEL ARCO AÓRTICO DERECHO EN PERRO SIN PELO DEL PERÚ – REPORTE DE UN CASO.

    OpenAIRE

    Grandez R., Ricardo; Bowler T., Brenda; Miguel de Priego G., Claudia; Yi A., Pedro; Torres P., Luis; Valencia L., Roberto

    2012-01-01

    Un canino de la raza Perro sin Pelo del Perú, de dos meses de edad, fue atendido con historia de regurgitación por un mes y pérdida progresiva de su condición corporal desde el destete. Al examen clínico presentó un estado de alerta y baja condición corporal. El paciente recibió tratamiento de sostén y se le realizó estudios imagenológicos, radiografía cervical, torácica y esofagografía, evidenciando una dilatación de esófago craneal al corazón. Se realizó la eutanasia a solicitud del propiet...

  15. Lipotransferencia en piernas con o sin fasciotomía subcutánea de la aponeurosis tibial posterior

    Directory of Open Access Journals (Sweden)

    I.R. Añorve-Borquez

    2014-03-01

    Full Text Available La lipotransferencia en muslos y piernas es un procedimiento muy poco empleado como complemento a la lipoescultura, siendo ésta una zona muy importante para dar más armonía y belleza al contorno corporal. Analizamos 139 procedimientos de lipotrasnferencia en muslos y piernas, ésta última complementada con o sin fasciotomía subcutánea de la aponeurosis tibial posterior o fascia profunda de la pierna. Describimos la técnica y las cantidades de grasa empleadas según zonas disminuyendo al mínimo las complicaciones y reacciones secundarias, que cuando se producen en las piernas, y si no se ha realizado la fasciotomía, puede confundir con otras patologías tales como es el síndrome compartimental y/o la trombosis venosa profunda.

  16. Religious celebration and artistic virtuosity in Los Sirgueros de la Virgen sin original pecado, by Francisco Bramón

    Directory of Open Access Journals (Sweden)

    Eduardo Francisco Hopkins Rodríguez

    2013-11-01

    Full Text Available Abstract:This article tries to deepen into the rhetoric, theological and autobiographic mechanisms that lie under Los Sirgueros de la Virgen sin original pecado by Francisco Bramón (1620. A divine pastoral romance conceived to celebrate the Immaculate Conception of Mary, dogma still under debate during the XVIIth Century, but with a strong support among the Spaniards, both in Spain and its American colonies. An opportunity that Bramón grabbed not only to honor the Immaculate, but also to denounce the poor conditions that suffer authors in the New Spain through a complex erudition structure. Resumen:Este artículo intenta profundizar en los mecanismos retóricos, teológicos y autobiográfico que están detrás de Los Sirgueros de la Virgen sin original pecado de Francisco Bramón (1620. Una novela pastoril a lo divino concebida para celebrar la Inmaculada Concepción de María, dogma aún en debate en el siglo XVII, pero con una fuerte devoción entre los españoles, tanto en España como en sus colonias americanas. Una oportunidad que Bramón aprovechó no solo para honrar a la Inmaculada, sino también para denunciar las condiciones precarias de los autores en la Nueva España a través de un complejo edificio de erudición.

  17. Haploinsufficiency of MeCP2-interacting transcriptional co-repressor SIN3A causes mild intellectual disability by affecting the development of cortical integrity.

    Science.gov (United States)

    Witteveen, Josefine S; Willemsen, Marjolein H; Dombroski, Thaís C D; van Bakel, Nick H M; Nillesen, Willy M; van Hulten, Josephus A; Jansen, Eric J R; Verkaik, Dave; Veenstra-Knol, Hermine E; van Ravenswaaij-Arts, Conny M A; Wassink-Ruiter, Jolien S Klein; Vincent, Marie; David, Albert; Le Caignec, Cedric; Schieving, Jolanda; Gilissen, Christian; Foulds, Nicola; Rump, Patrick; Strom, Tim; Cremer, Kirsten; Zink, Alexander M; Engels, Hartmut; de Munnik, Sonja A; Visser, Jasper E; Brunner, Han G; Martens, Gerard J M; Pfundt, Rolph; Kleefstra, Tjitske; Kolk, Sharon M

    2016-08-01

    Numerous genes are associated with neurodevelopmental disorders such as intellectual disability and autism spectrum disorder (ASD), but their dysfunction is often poorly characterized. Here we identified dominant mutations in the gene encoding the transcriptional repressor and MeCP2 interactor switch-insensitive 3 family member A (SIN3A; chromosome 15q24.2) in individuals who, in addition to mild intellectual disability and ASD, share striking features, including facial dysmorphisms, microcephaly and short stature. This phenotype is highly related to that of individuals with atypical 15q24 microdeletions, linking SIN3A to this microdeletion syndrome. Brain magnetic resonance imaging showed subtle abnormalities, including corpus callosum hypoplasia and ventriculomegaly. Intriguingly, in vivo functional knockdown of Sin3a led to reduced cortical neurogenesis, altered neuronal identity and aberrant corticocortical projections in the developing mouse brain. Together, our data establish that haploinsufficiency of SIN3A is associated with mild syndromic intellectual disability and that SIN3A can be considered to be a key transcriptional regulator of cortical brain development.

  18. Salud, calidad de vida y consumo de sustancias en función del tiempo en situación sin hogar

    Directory of Open Access Journals (Sweden)

    Sonia Panadero-Herrero

    2014-01-01

    Full Text Available Este artículo tiene como objetivo principal conocer las características diferenciales de aquellas personas que están "recién" llegadas a la situación sin hogar frente a aquellas que llevan un largo tiempo en dicha situación. Concretamente en este artículo se presentan los resultados de la comparación en diferentes variables (calidad de vida, salud, etc. entre personas sin hogar que llevaban menos de un año en esa situación y personas sin hogar que llevaban más de 5 años, con la intención de profundizar en el efecto de la situación sin hogar e identificar variables diferenciales que permitan avanzar en la identificación de necesidades específicas, favoreciendo así la planificación de servicios y recursos ajustados a las necesidades de cada grupo y momento. Los resultados apuntan diferencias importantes entre ambos grupos que parecen indican un mayor deterioro entre aquellos que llevan más tiempo en la situación sin hogar (mayor consumo de alcohol y otras sustancias, más discapacidades, etc. así como unas mayores carencias (duermen en mayor medida literalmente en la calle, ejercen en mayor medida la mendicidad, etc..

  19. Total lymphoid irradiation

    International Nuclear Information System (INIS)

    Anon.

    1980-01-01

    An outline review notes recent work on total lymphoid irradiation (TLI) as a means of preparing patients for grafts and particularly for bone-marrow transplantation. T.L.I. has proved immunosuppressive in rats, mice, dogs, monkeys and baboons; when given before bone-marrow transplantation, engraftment took place without, or with delayed rejection or graft-versus-host disease. Work with mice has indicated that the thymus needs to be included within the irradiation field, since screening of the thymus reduced skin-graft survival from 50 to 18 days, though irradiation of the thymus alone has proved ineffective. A more lasting tolerance has been observed when T.L.I. is followed by an injection of donor bone marrow. 50% of mice treated in this way accepted allogenic skin grafts for more than 100 days, the animals proving to be stable chimeras with 50% of their peripheral blood lymphocytes being of donor origin. Experiments of a similar nature with dogs and baboons were not so successful. (U.K.)

  20. The total artificial heart.

    Science.gov (United States)

    Cook, Jason A; Shah, Keyur B; Quader, Mohammed A; Cooke, Richard H; Kasirajan, Vigneshwar; Rao, Kris K; Smallfield, Melissa C; Tchoukina, Inna; Tang, Daniel G

    2015-12-01

    The total artificial heart (TAH) is a form of mechanical circulatory support in which the patient's native ventricles and valves are explanted and replaced by a pneumatically powered artificial heart. Currently, the TAH is approved for use in end-stage biventricular heart failure as a bridge to heart transplantation. However, with an increasing global burden of cardiovascular disease and congestive heart failure, the number of patients with end-stage heart failure awaiting heart transplantation now far exceeds the number of available hearts. As a result, the use of mechanical circulatory support, including the TAH and left ventricular assist device (LVAD), is growing exponentially. The LVAD is already widely used as destination therapy, and destination therapy for the TAH is under investigation. While most patients requiring mechanical circulatory support are effectively treated with LVADs, there is a subset of patients with concurrent right ventricular failure or major structural barriers to LVAD placement in whom TAH may be more appropriate. The history, indications, surgical implantation, post device management, outcomes, complications, and future direction of the TAH are discussed in this review.

  1. PROPAGACIÓN POR ESTACAS JUVENILES DEL BALSO BLANCO (Heliocarpus americanus L. Sin. H. popayanensis UTILIZANDO PROPAGADORES DE SUBIRRIGACIÓN PROPAGATION OF WHITE BALSUM (Heliocarpus americanus L. Sin. H. popayanensis CUTTINGS USING NONMIST PROPAGATORS

    Directory of Open Access Journals (Sweden)

    Carolina Vásquez Restrepo

    2006-12-01

    Full Text Available El mercado mundial de edulcorantes orgánicos es una oportunidad para la panela, producto básico de la canasta familiar que representa ingresos importantes para la población rural colombiana. El balso blanco (Heliocarpus americanus L. Sin. H. popayanensis Hook & Arn. es la especie más usada en procesos de clarificación de la panela en Antioquia y las zonas cañeras húmedas colombianas. Pero la extracción de la corteza de árboles obtenidos de la regeneración natural comienza a ser insostenible, por el daño causado a los individuos y la presión creciente a este recurso. La prohibición del uso de sustancias químicas en procesos de clarificación de panela ha aumentado la demanda de la corteza del balso blanco. En este trabajo se estimó el enraizamiento de estacas juveniles de balso blanco, por propagadores de subirrigación. Se realizaron dos experimentos, utilizando ácido anaftalenacético (ANA. En el primero se evaluó el efecto del transporte, cicatrizante y sustrato sobre el enraizamiento de las estacas de balso blanco. El mejor medio de transporte fue en cristales de hidrogel para mantener la humedad de las estacas, sin utilizar cicatrizante y sembrándolas en el sustrato tierra (55 % de enraizamiento. En el segundo se analizó la influencia de la intensidad lumínica y el área foliar en el porcentaje de enraizamiento de las estacas. El más alto enraizamiento se obtuvo con el tratamiento de doble sombra y un área foliar de 20 cm² (25 % de enraizamiento. Aunque los mejores resultados indican un relativo éxito en el uso de medios de enraizamiento, es una primera aproximación para propagar esta especie que necesita ser protegida.The world market of organic edulcorants is an opportunity for “panela”, a basic domestic consumption product that provides important income to rural population. White balsum (Heliocarpus americanus L. Sin. H. popayanensis Hook & Arn. is the most used species in the panela clarification processes in

  2. Protective effects of Lagerstroemia speciosa on 3-morpholinosydnonimine (SIN-1)-induced oxidative stress in HIT-T15 pancreatic β cells.

    Science.gov (United States)

    Song, Jia-Le; Zhao, Xin; Wang, Qiang; Zhang, Ting

    2013-05-01

    Reactive oxygen species (ROS)-induced pancreatic β cell death affects insulin secretion and is important in the pathogenesis of diabetes. Lagerstroemia speciosa, a traditional folk medicine, has been used for t he prevention and treatment of diabetes. However, whether Lagerstroemia speciosa has a cytoprotective effect on pancreatic β cells remains to be elucidated. The present study aimed to investigate the cytoprotective effects of hot water extracts from Lagerstroemia speciosa leaves (LWE) on 3-morpholinosydnonimine (SIN-1)-induced oxidative damage in Syrian hamster pancreatic insulinoma HIT-T15 cells. The HIT-T15 cells were first treated with SIN-1 (50 µM) for 24 h and then co-incubated with LWE for 48 h. SIN-1 significantly decreased HIT-T15 cell viability (PHIT-T15 cells in a dose‑dependent manner. To further investigate the protective effects of LWE on SIN-1‑induced oxidative stress in HIT-T15 cells, the cellular levels of ROS, lipid peroxidation and endogenous antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-px), were determined. LWE decreased the intracellular levels of ROS and lipid peroxidation, and increased the activities of antioxidant enzymes. These results suggest that LWE has a cytoprotective effect against SIN-1‑induced oxidative stress in HIT-T15 cells through the inhibition of lipid peroxidation, a decrease in ROS levels and an increase in antioxidant enzyme activity. In addition, LWE increased insulin secretion in SIN-1-treated HIT-T15 cells. Our results suggested that LWE were effective in the treatment of diabetes. Further studies are required to study the anti-diabetic molecular mechanism in a cell model.

  3. Incapacidad laboral total

    Directory of Open Access Journals (Sweden)

    Orlando Díaz Tabares

    1997-04-01

    Full Text Available Se realizó un estudio longitudinal, descriptivo y retrospectivo con el objetivo de conocer el comportamiento de la incapacidad permanente para el trabajo en el municipio "San Cristóbal" durante el decenio 1982-1991, y se aplicó el método de encuesta por el que se recogieron datos que fueron extraídos del modelo oficial de peritaje médico laboral y de la entrevista con el peritado. Los resultados fueron plasmados en tablas de contingencias donde se relacionan las variables por cada año estudiado, y se aplicó la prueba estadística de chi cuadrado. El número de individuos dictaminados con incapacidad laboral total fue de 693; predominó en reportes el año 1988 con 114 casos y muy discretamente el sexo femenino sobre el masculino, el grupo etáreo de 45 a 54 años con 360 casos y la artrosis como entidad valorada por ortopedia, con análisis estadísticos significativos. No resultó estadísticamente significativo, el predominio de la hipertensión arterial sistémica entre las entidades valoradas por la especialidad de medicina interna como causas de incapacidad laboral. Fue muy significativa la variación del número de dictaminados por la comisión en cada uno de los años estudiados y que el porcentaje de ellos que se encontraban realizando trabajos que demandan esfuerzo físico de moderado a intenso al momento de aplicar la encuesta, ascendió al 64,9.A longitudinal, descriptive and retrospective study was conducted in order to know the behavior of permanent labor disability at the municipality of San Cristóbal during 1982-1991. A survey was done to collect data taken from the official model of medical inspections and from the interview with the disabled worker. The results were shown in contingency tables where the variables are related by every year studied. The chi square statistical test was applied. The number of individuals with labor disability was 693. As for reports, the year 1988 predominated with 114. There was a discreet

  4. Regulación del ciclo vesicular sináptico por las quinasas dependientes de GMPc en neuronas grabulares de cerebelo

    OpenAIRE

    Collado Alsina, Marina Andrea

    2016-01-01

    La comunicación entre las neuronas ocurre en regiones anatómicamente identificables denominadas sinapsis. Existen dos tipos de transmisión sináptica, las sinapsis químicas y las eléctricas, aunque predominan las sinapsis químicas. En este tipo de sinapsis, la comunicación neuronal ocurre en zonas especializadas de los axones, denominados terminales sinápticos, los cuales almacenan en su interior pequeñas vesículas que contienen un neurotransmisor. Ante la llegada de un potencial de acción al ...

  5. Método y sistema para la medición directa y sin contacto de la temperatura superficial en un cable

    OpenAIRE

    Mañana Canteli, Mario; Arroyo Gutiérrez, Alberto; Castro Alonso, Pablo Bernardo; Madrazo Maza, Alfredo; Valli, Cristina Alice; González Diego, Antonio; Martínez Torre, Raquel; Laso Pérez, Alberto; Domingo Fernández, Rodrigo; Sierra Molleda, Alberto

    2014-01-01

    Sistema de medición directa y sin contacto de la temperatura superficial en un cable, que comprende al menos un cable cuya temperatura desea ser monitorizada al menos un cuerpo de medición térmica envolviendo cada cable, tal que cada cuerpo de medición térmica envuelve a un único cable; y al menos un sensor de temperatura sin contacto que enfoca al menos un cuerpo de medición térmica, estando cada cuerpo de medición térmica configurado para incrementar el área efectiva sobre el cual incide al...

  6. Efectos a largo plazo de los síntomas depresivos en una tarea de memoria de trabajo con y sin interferencia atencional

    OpenAIRE

    Silvia Botelho de Oliveira; Laura Fernanda Jaimes Alvarado; Carlos Arturo Conde Cotes

    2015-01-01

    La neurobiología de la depresión involucra cambios estructurales del sistema nervioso relacionados con procesos cognitivos como la memoria y la atención. El objetivo del presente estudio fue evaluar el efecto a largo plazo de la sintomatología depresiva (SD) en una tarea de memoria de trabajo visual con y sin interferencia atencional en estudiantes universitarios. Se utilizó un diseño factorial de 2 × 2 en el cual las variables independientes fueron la condición clínica (con SD y sin SD) y la...

  7. Nevadas en el Sudeste Bonaerense: climatología sinóptica y un caso de estudio

    Directory of Open Access Journals (Sweden)

    Paola Salio

    2006-12-01

    Full Text Available Este trabajo realiza una estadística de la frecuencia de las nevadas ocurridas sobre el sudeste de la provincia de Buenos Aires durante un período de 35 años (1960-2004. Utilizando información de tiempo presente se detectaron 32 eventos de nevada, 7 de los cuales produjeron nieve en más de una estación sinóptica. A fin de comprender los patrones de circulación, se realiza una climatología sinóptica de las incursiones de aire frío que son responsables de nevadas en la región de estudio. Dichos patrones se caracterizan por anomalías extremas en las vaguadas asociadas a frentes fríos y en las cuñas posfrontales que denotan la intensidad de dichos sistemas. El campo de anomalías de altura geopotencial muestra en los casos de nieve generalizada un mínimo sobre la vaguada frontal que duplica la intensidad de la obtenida en los casos de nieve aislada. El intenso régimen ciclónico favorece la convergencia en niveles bajos y el fuerte enfriamiento, evidente en las anomalías del campo térmico en niveles medios, indicando la inestabilidad generada en la masa de aire que es conducida hacia el norte sobre la costa patagónica y el Mar Argentino. En un caso particular de nevada generalizada, asociada a una fuerte incursión de aire frío ocurrida el 10 de julio de 2004 sobre el sudeste de la costa bonaerense, se analiza la situación sinóptica utilizando el modelo "Sistema de Modelado Atmosférico Regional" (RAMS como herramienta de diagnóstico y se la relaciona con las muestras previamente encontradas, caracterizando la masa de aire polar y su evolución. La nevada se asocia a una inestabilización sostenida de la masa de aire, favorecida por calentamiento y humedecimiento en una trayectoria dominantemente marítima y por convergencia en un régimen ciclónico en niveles bajos.This paper presents a statistic of the frequency of snow-fall occurred over the southeast of Buenos Aires province over a 35 year period (1960-2004. Considering

  8. Homosexual Desire Displayed in El lugar sin límites, by Arturo Ripstein / Visualizaciones del deseo homosexual en El lugar sin límites, de Arturo Ripstein

    Directory of Open Access Journals (Sweden)

    Dieter Ingenschay

    2016-09-01

    Full Text Available El siguiente artículo analiza la película El lugar sin límites (1977 de Arturo Ripstein, basada en la novela homónima de José Donoso (1966. Ambas obras se conocen como ejemplos tempranos de un discurso sobre la homosexualidad dentro de las sociedades homófobas latinoamericanas de la era antes de Foucault. Su meta es mostrar las diferencias específicas «esenciales» entre la novela y la película con respecto al tema de los problemas de género y del deseo homosexual en particular. Cuando Ripstein pidió el guión a Manuel Puig, quería ganar la colaboración de una voz «auténticamente» gay, pero más tarde Puig no reconoció su autoría. Las dos obras disponen de técnicas específicas para visualizar la «perturbación de géneros», a saber: métodos gramaticales en el caso de la novela, y el uso de colores simbólicos en el caso de la película. Ésta última muestra, más claramente que la novela, el carácter performativo del género. Aunque la película aborda cuestiones como la homofobia, la represión y los inicios de una liberación sexual –y por ello podría relacionarse con el popular cine de fichera–, su principal logro es mostrar, de manera consciente e inédita, el proceso emancipatorio de un gay, travesti en este caso. Si hay una persona «trágica» en esta película, ya no es La Manuela, el travesti, sino Pancho, el macho y homosexual.Palabras clave: Ripstein, Donoso, El lugar sin límites, homosexualidad en Latinoamérica, Gender Trouble (perturbación de género en Latinoamérica, homofobia en Latinoamérica, emancipación gay en Latinoamérica.AbstractThe following article analyzes Arturo Ripstein’s film El lugar sin límites (1977, based on José Donoso’s homonymous novel (1966. Both are well-known early examples of a fictional discourse on homosexuality within the homophobic Latin American societies of pre-Foucauldian times. Its aim is to show the specific «essential» difference between the novel and

  9. La salvación sin mediaciones según Marción y la respuesta de Tertuliano

    Directory of Open Access Journals (Sweden)

    Samuel Fernández E.

    2001-01-01

    Full Text Available Marción profesa un severo pesimismo cosmológico y antropológico, que tiene su punto de partida en la pregunta acerca del origen del mal y en una comprensión literal de algunos versículos bíblicos. Esta valoración repercute en una valoración también negativa del Creador (confirmada por la imperfección del mundo y el pecado del hombre. El Dios Verdadero, por su parte es totalmente extranjero respecto del hombre y del mundo. Este carácter extranjero, propio del Dios Supremo, impide que este se valga de las realidades creadas para revelarse. El mundo es adversario del Dios Bueno. Por lo tanto, ninguna realidad creada puede servir de mediación entre el alma del hombre y el Verdadero Dios: se plantea una salvación sin mediaciones. La última parte del artículo estudia sumariamente la reacción de Tertuliano, que insiste en una justa valoración de las realidades creadas: hay que admitir, a la vez, una cierta distancia y una cierta familiaridad entre Dios y el mundo.Marcion confesses a deep cosmological and anthropological pessimis, derived from the question about the origin of evil and form a literal understanding of the some biblical verses. Such valorisation also has repercussions on a negative valorisation of the Creator (confirmed by the imperfection of the world and the sin of man. The real God, is an entire stranger to man and the world. Such foreign character, characteristic of the Supreme God, prevents Him from revealing Himself through the created realities. The world is the good God’s adversary, so no created reality may serve as mediation between the human soul and the True God: He advocates a salvation without mediations. The final part of article presents a summary of Tertulian’s reaction, who stresses the just valorisation of the created realities: the acceptance of both a certain distance and familiarity between God and the World.

  10. Cirugía sin circulación extracorpórea: Cambios hemodinámicos y tolerancia

    Directory of Open Access Journals (Sweden)

    Fabián Crespo

    2003-06-01

    Full Text Available Se analizaron los cambios hemodinámicos producidos en 30 pacientes que fueron sometidos a cirugía de revascularización miocárdica sin circulación extracorpórea. Los parámetros medidos mediante el doppler esofágico fueron: frecuencia cardíaca, presión arterial media, gasto cardíaco, índice cardíaco, resistencia periférica, volumen sistólico y presión venosa central. Los controles se realizaron durante la disección de la arteria mamaria (basal, durante la realización de cada anastomosis y 5 min después del retiro del inmovilizador (final. Se utilizó el Octopus como estabilizador epicárdico. La frecuencia cardíaca aumentó durante la realización de las anastomosis de las arterias DA, CX y DP. La presión arterial media disminuyó significativamente durante la realización de la anastomosis a la CX. El volumen sistólico disminuyó durante la realización de la anastomosis a la DA y CX. Los valores de la presión venosa central aumentaron durante la realización de las anastomosis de las arterias CX y DP. En la mayoría de los casos los cambios hemodinámicos que se produjeron en la cirugía sin circulación extracorpórea pudieron corregirse y no imposibilitaron la realización de esta técnicaThe hemodynamic changes observed in 30 patients that underwent myocardial revascularization surgery without extracorporeal circulation were analyzed. The parameters measured by esophageal doppler were the following: heart rate, mean arterial pressure, heart output, peripheral resistance, systolic volume and central venous pressure. The controls were carried out during the dissection of the mammary artery (basal, during the performance of anastomosis and 5 minutes after the removal of the immobilizer (final The Octupus was used as an epicardiac stabilizer. Heart rate increased during the anastomosis of the DA, CX and DP arteries. The mean arterial pressure decreased significantly during the anastomosis of CX. The systolic volume was

  11. ¿Con o sin ancestros?: vigencia de lo ancestral en la Amazonía peruana

    Directory of Open Access Journals (Sweden)

    Thomas Mouriès

    2014-06-01

    Full Text Available La existencia o no de ancestros en la Amazonía indígena ha sido objeto de importantes debates. Sin embargo, los líderes de la región no dudan en llamar ‘ancestrales’ sus saberes, normas o territorios, en un sentido que, desde un punto de vista académico, puede parecer enigmático. «Ancestrales, pero… ¿con o sin ancestros?», preguntaría entonces, confuso, el antropólogo. En este artículo propongo aportar elementos de respuesta a esta pregunta a través del caso peruano. Primero analizo cómo los líderes indígenas amazónicos, conectándose al circuito del derecho internacional, adoptan la noción jurídica de ‘posesión ancestral’ del territorio para adaptarla al ámbito político. Este planteamiento rinde cuenta de la generalización y uniformización reciente del vocablo ‘ancestral’ pero deja pendiente el problema de su eventual articulación con las cosmologías indígenas que pretende reflejar. Por eso, en la segunda parte, intento sondear sobre la pertinencia de la categoría de ‘ancestro’ en la Amazonía indígena, recordando brevemente el debate académico para ir definiendo en qué medida esta categoría puede cobrar sentido. A partir del testimonio de un experimentado líder awajún, la tercera parte permite, entonces, volver más explícitos los diferentes sentidos y planos referenciales que despliega la referencia a lo ancestral, mostrando cómo los indígenas amazónicos no solo adoptan elementos conceptuales y discursivos externos, sino que al mismo tiempo los transforman a partir de sus propias singularidades cosmológicas y perspectivas políticas.

  12. Características antioxidantes, fisicoquímicas y microbiológicas de jugo fermentado y sin fermentar de tres variedades de pitahaya (Hylocereus spp

    Directory of Open Access Journals (Sweden)

    Carlos Enrique Ochoa-Velasco

    2012-01-01

    Full Text Available Al jugo de pitahaya de tres variedades (roja, rosa y blanca se le evaluó el pH, sólidos solubles totales, acidez titulable, color, compuestos fenólicos, capacidad antioxidante, mientras que al jugo de pitahaya fermentado con Saccharomyces cerevisiae se le evaluaron además el número de bacterias mesófilas aerobias, mohos y levaduras y contenido alcohólico. Los sólidos solubles totales y pH disminuyeron en el jugo fermentado en todas las variedades de pitahaya. El contenido de compuestos fenólicos fue mayor en el jugo de pitahaya roja, seguido de la rosa y la blanca con valores promedios de 45,3, 32,1y 24,6 mg de ácido gálico/100 mL de jugo, respectivamente. Por ende, la capacidad antioxidante fue superior en el jugo de pitahaya roja (160,84 mg de Trolox/100 mL de jugo. La fermentación del jugo de pitahaya incrementó el contenido de compuestos fenólicos (variando de 45,31 a 51,38 mg de ácido gálico/100 mL de jugo, en pitahaya roja, aunque disminuyó la capacidad antioxidante (variando de 124,51 a 82,96 mg de Trolox/100 mL de jugo, en pitahaya rosa. El contenido de alcohol de los jugos fermentados fue entre 2,9 y 3,9 % (v/v. Al final de la fermentación la carga máxima de mohos y levaduras (1580 UFC/mL la presentó el jugo fermentado de pitahaya blanca. Sin embargo, después de la pasteurización el crecimiento microbiano en todos los tratamientos fue menor a 10 UFC/mL. La elaboración de subproductos como el jugo fermentado es una alternativa viable para la comercialización de productos derivados de la pitahaya.

  13. Memory: sins and virtues

    OpenAIRE

    Schacter, Daniel L.

    2013-01-01

    Memory plays an important role in everyday life but does not provide an exact and unchanging record of experience: research has documented that memory is a constructive process that is subject to a variety of errors and distortions. Yet these memory “sins” also reflect the operation of adaptive aspects of memory. Memory can thus be characterized as an adaptive constructive process, which plays a functional role in cognition but produces distortions, errors, or illusions as a consequence of d...

  14. At sanse sin perception

    DEFF Research Database (Denmark)

    Thomsen, Bodil Marie Stavning

    2015-01-01

    En aktualiserende refleksion over perceptionsformernes belysning i Hotel Pro Formas forestilling “Hvorfor bli'r det nat, mor” (1989).......En aktualiserende refleksion over perceptionsformernes belysning i Hotel Pro Formas forestilling “Hvorfor bli'r det nat, mor” (1989)....

  15. Perfil de los niños, niñas y adolescentes sin cuidado parental en Colombia

    Directory of Open Access Journals (Sweden)

    Ernesto Durán Strauch

    2009-01-01

    Full Text Available La situación de niños, niñas y adolescentes (NNA sin cuidado parental es un tema poco estudiado en el país. Se realizó una caracterización del problema, a partir de fuentes primarias y secundarias, para ello se utilizaron varias estrategias metodológicas: análisis documental, análisis de bases de datos e informes estadísticos, entrevistas semiestructuradas, grupos de discusión y talleres. Todas las situaciones de riesgo para que falte el cuidado parental, se presentan en Colombia: pobreza, desplazamiento, migraciones nacionales e internacionales, desastres naturales, conflicto armado, discapacidad, violencia intrafamiliar, entre otros. Los datos presentados muestran que la magnitud del problema es grande y son graves sus implicaciones en la vulneración de derechos La respuesta social organizada ante el problema es limitada tanto en la prevención como en el restablecimiento de derechos.

  16. An array of cold-electron bolometers with SIN tunnel junctions and JFET readout for cosmology instruments

    International Nuclear Information System (INIS)

    Kuzmin, L

    2008-01-01

    A novel concept of the parallel/series array of Cold-Electron Bolometers (CEB) with Superconductor-Insulator-Normal (SIN) Tunnel Junctions has been proposed. The concept was developed specially for matching the CEB with JFET amplifier at conditions of high optical power load. The CEB is a planar antenna-coupled superconducting detector with high sensitivity. For combination of effective HF operation and low noise properties the current-biased CEBs are connected in series for DC and in parallel for HF signal. A signal is concentrated from an antenna to the absorber through the capacitance of the tunnel junctions and through additional capacitance for coupling of superconducting islands. Using array of CEBs the applications can be considerably extended to higher power load by distributing the power between N CEBs and decreasing the electron temperature. Due to increased responsivity the noise matching is so effective that photon NEP could be easily achieved at 300 mK with a room temperature JFET for wide range of optical power loads. The concept of the CEB array has been developed for the BOOMERanG balloon telescope and other Cosmology instruments

  17. CHILE, 1970-1973 UN AULA ABIERTA. ACERCA DE UNA FÁBRICA SIN PATRONES * -- RELATO TESTIMONIO --

    Directory of Open Access Journals (Sweden)

    Carlos Falaschi

    2014-09-01

    Full Text Available Érase el año 1972 en Santiago de Chile, el Chile de la Unidad Popular con Salvador Allende como Presidente. Este había obtenido mayoría de votos, había sido confirmado por el Parlamento y asumido el 3 de noviembre de 1970. Los cambios estructurales iban siendo palpables y progresivos para el pueblo, que cantaba en las concentraciones: - ”Luchando, creando, poder popular”. Entre ellos, los planes de  alfabetización, de  nivelación primaria  y  secundaria de  adultos; el  proceso de nacionalización del cobre; la estatización de empresas estratégicas y la constitución del Área Social de la economía; etc. En esta última y a partir de un censo ad-hoc de los trabajadores por el INACAP-Instituto Nacional de Capacitación, se organizaron y pusieron en marcha los cursos para aquellos sin escolaridad o con escolaridad incompleta. Muchos de estos cursos se daban en las propias fábricas, repartiéndose una hora del tiempo de producción de la empresa con otra hora del tiempo libre de los inscriptos.

  18. A three axis turntable's online initial state measurement method based on the high-accuracy laser gyro SINS

    Science.gov (United States)

    Gao, Chunfeng; Wei, Guo; Wang, Qi; Xiong, Zhenyu; Wang, Qun; Long, Xingwu

    2016-10-01

    As an indispensable equipment in inertial technology tests, the three-axis turntable is widely used in the calibration of various types inertial navigation systems (INS). In order to ensure the calibration accuracy of INS, we need to accurately measure the initial state of the turntable. However, the traditional measuring method needs a lot of exterior equipment (such as level instrument, north seeker, autocollimator, etc.), and the test processing is complex, low efficiency. Therefore, it is relatively difficult for the inertial measurement equipment manufacturers to realize the self-inspection of the turntable. Owing to the high precision attitude information provided by the laser gyro strapdown inertial navigation system (SINS) after fine alignment, we can use it as the attitude reference of initial state measurement of three-axis turntable. For the principle that the fixed rotation vector increment is not affected by measuring point, we use the laser gyro INS and the encoder of the turntable to provide the attitudes of turntable mounting plat. Through this way, the high accuracy measurement of perpendicularity error and initial attitude of the three-axis turntable has been achieved.

  19. Cuerpo reconocido: Formación para la interacción sin violencia en la escuela primaria

    Directory of Open Access Journals (Sweden)

    Ruth Milena Páez Martínez

    2009-01-01

    Full Text Available Las cuestiones ¿por qué se presentan las interacciones violentas entre las personas menores? ¿cómo se caracterizan? ¿qué mecanismos de reflexión y posibles acciones pueden orientar y abordar los maestros y maestras?, movilizan el desarrollo del presente artículo a lo largo de tres reflexiones analíticas: la primera, en torno a la experiencia de sí mismo y del otro por el cuerpo, como una condición necesaria para el autoconocimiento y el reconocimiento; la segunda, referida a la experiencia del juego en los niños y niñas escolares, como opción de formación en la interacción "no violenta", en tanto hace posible la inmersión en un mundo nuevo en donde el otro, incluso el extraño, pueda interactuar con sus pares; y se dejan algunas pistas sobre la experiencia del cuerpo del propio maestro o maestra en la formación de los niños y niñas. Todas ellas, como posibilidad y apuesta para la interacción sin violencia en los niños y niñas de primara, gracias al reconocimiento del cuerpo.

  20. Ángeles Sin Fronteras , A.C. y el proceso de deportación a Mexicali, Baja California

    Directory of Open Access Journals (Sweden)

    Tatiana E. Lara San Luis

    2014-01-01

    Full Text Available Las políticas migratorias estadounidenses que buscan a toda costa repatriar mexicanos desde los Estados Unidos no son nuevas. Contrario a lo que se pueda pensar, la deportación y repatriación hacia la frontera norte de México forman parte de un largo proceso histórico. En el caso de la frontera noroeste del país, la necesidad de dar solución a las deportaciones masivas, iniciadas luego de la década de 1990, o más bien, mejorar las condiciones en que se realizan, ha impulsado la formación de asociaciones —civiles o religiosas— destinadas a proporcionar apoyo a los connacionales recién llegados. Un ejemplo claro de ellas es la conformada por migrantes deportados y ciudadanos de la ciudad de Mexicali, Ángeles Sin Fronteras, quienes a partir de la puesta en marcha del Hotel del Migrante, proporcionan alojamiento y comida de manera gratuita a varones deportados a dicha población. Asimismo, permiten la participación activa de la comu � nidad a partir de donaciones y la interacción de los migrantes en la que se vuelve su nueva ciudad, generando mecanismos de sobrevivencia para quienes han quedado a la intemperie.

  1. Estudio de la intercara de una preforma híbrida infiltrada sin presión

    Directory of Open Access Journals (Sweden)

    Rams, J.

    2010-12-01

    Full Text Available This work presents an interfacial characterization of the matrix/reinforcement interface of an aluminium matrix composite reinforced with Saffil fibres and alumina particles was manufactured using the PrimexTM pressureless infiltration process. Scanning electron microscopy and energy dispersive X-ray spectroscopy were used to carry out the microstructural and chemical characterization of the composite material. In addition, a mechanical characterization was conducted by the nanoindentation technique. This research concludes that the composite presents a good bonding between the matrix and the reinforcements.

    En este trabajo se presenta la caracterización de la intercara matriz/refuerzo en un compuesto de matriz de aluminio reforzado con fibras de Saffil y partículas de alúmina, fabricado mediante el proceso de infiltración sin presión, Primex. La caracterización microestructural y química del material compuesto se ha realizado mediante microscopía electrónica de barrido y mediante análisis semicuantitativo por energía dispersiva de rayos-X. Asimismo, se ha realizado una caracterización mecánica del material compuesto utilizando la técnica de nanoindentación. De la investigación se concluye que se tiene una buena unión entre los refuerzos y la matriz.

  2. THE SINS/zC-SINF SURVEY OF z ∼ 2GALAXY KINEMATICS: THE NATURE OF DISPERSION-DOMINATED GALAXIES

    International Nuclear Information System (INIS)

    Newman, Sarah F.; Genzel, Reinhard; Förster Schreiber, Natascha M.; Buschkamp, Peter; Davies, Ric; Eisenhauer, Frank; Kurk, Jaron; Lutz, Dieter; Shapiro Griffin, Kristen; Mancini, Chiara; Renzini, Alvio; Lilly, Simon J.; Carollo, C. Marcella; Peng, Yingjie; Bouché, Nicolas; Burkert, Andreas; Cresci, Giovanni; Genel, Shy; Hicks, Erin K. S.; Naab, Thorsten

    2013-01-01

    We analyze the spectra, spatial distributions, and kinematics of Hα, [N II], and [S II] emission in a sample of 38, z ∼ 2.2 UV/optically selected star-forming galaxies (SFGs) from the SINS and zC-SINF surveys, 34 of which were observed in the adaptive optics mode of SINFONI and 30 of those contain data presented for the first time here. This is supplemented by kinematic data from 43 z ∼ 1-2.5 galaxies from the literature. None of these 81 galaxies is an obvious major merger. We find that the kinematic classification of high-z SFGs as ''dispersion dominated'' or ''rotation dominated'' correlates most strongly with their intrinsic sizes. Smaller galaxies are more likely ''dispersion-dominated'' for two main reasons: (1) the rotation velocity scales linearly with galaxy size but intrinsic velocity dispersion does not depend on size or may even increase in smaller galaxies, and as such, their ratio is systematically lower for smaller galaxies, and (2) beam smearing strongly decreases large-scale velocity gradients and increases observed dispersion much more for galaxies with sizes at or below the resolution. Dispersion-dominated SFGs may thus have intrinsic properties similar to ''rotation-dominated'' SFGs, but are primarily more compact, lower mass, less metal enriched, and may have higher gas fractions, plausibly because they represent an earlier evolutionary state.

  3. Eficacia de un programa de entrenamiento en memoria en el mantenimiento de ancianos con y sin deterioro cognitivo

    Directory of Open Access Journals (Sweden)

    M.ª Dolores Calero García

    2006-01-01

    Full Text Available El objetivo del este estudio ha sido analizar el efecto de un entrenamiento en memoria en el mantenimiento cognitivo de ancianos con y sin deterioro cognitivo. Método: En la investigación han participado 98 ancianos (59 grupo tratamiento y 39 grupo control que han sido evaluados en tres momentos temporales (antes del entrenamiento, después del mismo y tras 9 meses con diversas pruebas de funcionamiento cognitivo. Las personas del grupo tratamiento han participado en un programa de entrenamiento en memoria de 14 sesiones. Resultados: Los resultados muestran que los ancianos del grupo tratamiento mejoran su rendimiento cognitivo en las evaluaciones posteriores al entrenamiento mientras que las del grupo control sufren un declive de tal manera que, aunque no existen diferencias significativas de partida entre grupos, éstas sí que se producen una vez introducida la fase de entrenamiento. Conclusiones: los resultados muestran los efectos positivos de este tipo de intervenciones cuando se trabaja con población anciana.

  4. Linfoma no Hodgkin primario de sistema nervioso central en un paciente pediátrico sin inmunodeficiencia relacionada

    Directory of Open Access Journals (Sweden)

    Rocío Cárdenas-Cardos

    2015-10-01

    Full Text Available El linfoma no Hodgkin primario de sistema nervioso central es una afección poco frecuente en la población pediátrica. No existen (o son pocas las recomendaciones o estudios clínicos que sean útiles para definir la mejor opción terapéutica. El objetivo de este trabajo es describir el caso de una niña con linfoma primario de sistema nervioso central, sin ninguna inmunodeficiencia asociada, y realizar de una revisión cualitativa de la literatura especializada sobre esta enfermedad en niños. Se ha postulado la posibilidad de cambios citogenéticos que pudieran explicar la heterogeneidad en el comportamiento de esta enfermedad pues se ha visto que es distinto al de otros linfomas en presentaciones habituales. La experiencia de tratamiento en niños con linfoma se basa en resultados de tratamientos obtenidos en pacientes adultos, con regímenes basados principalmente en antimetabolitos como metotrexato y citarabina. Aún es controvertida la utilidad de la radioterapia craneal, la cual sólo se recomienda en casos específicos.

  5. THE SINS/zC-SINF SURVEY OF z {approx} 2GALAXY KINEMATICS: THE NATURE OF DISPERSION-DOMINATED GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Newman, Sarah F.; Genzel, Reinhard [Department of Astronomy, Campbell Hall, University of California, Berkeley, CA 94720 (United States); Foerster Schreiber, Natascha M.; Buschkamp, Peter; Davies, Ric; Eisenhauer, Frank; Kurk, Jaron; Lutz, Dieter [Max-Planck-Institut fuer extraterrestrische Physik (MPE), Giessenbachstr. 1, D-85748 Garching (Germany); Shapiro Griffin, Kristen [Space Sciences Research Group, Northrop Grumman Aerospace Systems, Redondo Beach, CA 90278 (United States); Mancini, Chiara; Renzini, Alvio [Osservatorio Astronomico di Padova, Vicolo dell' Osservatorio 5, Padova I-35122 (Italy); Lilly, Simon J.; Carollo, C. Marcella; Peng, Yingjie [Institute of Astronomy, Department of Physics, Eidgenoessische Technische Hochschule, ETH Zuerich CH-8093 (Switzerland); Bouche, Nicolas [Universite de Toulouse, UPS-OMP, IRAP, Toulouse (France); Burkert, Andreas [Universitaets-Sternwarte Ludwig-Maximilians-Universitaet (USM), Scheinerstr. 1, Muenchen D-81679 (Germany); Cresci, Giovanni [Istituto Nazionale di Astrofisica Osservatorio Astronomico di Arcetri, Largo Enrico Fermi 5, I-50125 Firenze (Italy); Genel, Shy [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Hicks, Erin K. S. [Department of Astronomy, University of Washington, Box 351580, Seattle, WA 98195-1580 (United States); Naab, Thorsten, E-mail: sfnewman@berkeley.edu [Max-Planck Institute for Astrophysics, Karl Schwarzschildstrasse 1, D-85748 Garching (Germany); and others

    2013-04-20

    We analyze the spectra, spatial distributions, and kinematics of H{alpha}, [N II], and [S II] emission in a sample of 38, z {approx} 2.2 UV/optically selected star-forming galaxies (SFGs) from the SINS and zC-SINF surveys, 34 of which were observed in the adaptive optics mode of SINFONI and 30 of those contain data presented for the first time here. This is supplemented by kinematic data from 43 z {approx} 1-2.5 galaxies from the literature. None of these 81 galaxies is an obvious major merger. We find that the kinematic classification of high-z SFGs as ''dispersion dominated'' or ''rotation dominated'' correlates most strongly with their intrinsic sizes. Smaller galaxies are more likely ''dispersion-dominated'' for two main reasons: (1) the rotation velocity scales linearly with galaxy size but intrinsic velocity dispersion does not depend on size or may even increase in smaller galaxies, and as such, their ratio is systematically lower for smaller galaxies, and (2) beam smearing strongly decreases large-scale velocity gradients and increases observed dispersion much more for galaxies with sizes at or below the resolution. Dispersion-dominated SFGs may thus have intrinsic properties similar to ''rotation-dominated'' SFGs, but are primarily more compact, lower mass, less metal enriched, and may have higher gas fractions, plausibly because they represent an earlier evolutionary state.

  6. Indefensión producida por emplazamiento mediante edictos sin previo agotamiento de las vías ordinarias de comunicación personal

    OpenAIRE

    Vegas Torres, Jaime

    1994-01-01

    Al hilo del comentario de la STC 103/1993, se hace un completo repaso de los precedentes en la doctrina del TC sobre indefensión originada por actos de comunicación mediante edictos sin haber agotado antes las vías ordinarias de comunicación personal. Derecho Público II

  7. The deadly sins of high technology: Superphenix, Eurotunnel, Ariane 5..; Les peches capitaux de la haute technologie: Superphenix, Eurotunnel, Ariane 5..

    Energy Technology Data Exchange (ETDEWEB)

    Bell, R.; Jeanmougin, Ch

    1998-12-31

    Based on a detailed analysis of civil or military high technology projects (Superphenix reactor, English Channel tunnel, Ariane 5 launcher, etc..), mainly of European origin, this book reveals seven systematic sins in the realization of these projects: an abolishment of controls, a premature construction, a manumission of suppliers, a no-share of risks attitude, political manipulations, fraudulence and secrecy. (J.S.)

  8. Molecular characterization of the pSinB plasmid of the arsenite oxidizing, metallotolerant Sinorhizobium sp. M14 - insight into the heavy metal resistome of sinorhizobial extrachromosomal replicons.

    Science.gov (United States)

    Romaniuk, Krzysztof; Dziewit, Lukasz; Decewicz, Przemyslaw; Mielnicki, Sebastian; Radlinska, Monika; Drewniak, Lukasz

    2017-01-01

    Sinorhizobium sp. M14 is an As(III)-oxidizing, psychrotolerant strain, capable of growth in the presence of extremely high concentrations of arsenic and many other heavy metals. Metallotolerant abilities of the M14 strain depend upon the presence of two extrachromosomal replicons: pSinA (∼ 109 kb) and pSinB (∼ 300 kb). The latter was subjected to complex analysis. The performed analysis demonstrated that the plasmid pSinB is a narrow-host-range repABC-type replicon, which is fully stabilized by the phd-vapC-like toxin-antitoxin stabilizing system. In silico analysis showed that among the phenotypic gene clusters of the plasmid pSinB, eight modules are potentially involved in heavy metals resistance (HMR). These modules carry genes encoding efflux pumps, permeases, transporters and copper oxidases, which provide resistance to arsenic, cadmium, cobalt, copper, iron, mercury, nickel, silver and zinc. The functional analysis revealed that the HMR modules are active and have an effect on the minimal inhibitory concentration (MIC) values observed for the heterological host cells. The phenotype was manifested by an increase or decrease of the MICs of heavy metals and it was strain specific. The analysis of distribution of the heavy metal resistance genes, i.e. resistome, in Sinorhizobium spp. plasmids, revealed that the HMR modules are common in these replicons. © FEMS 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  9. Searching for Stable SinCn Clusters: Combination of Stochastic Potential Surface Search and Pseudopotential Plane-Wave Car-Parinello Simulated Annealing Simulations

    Directory of Open Access Journals (Sweden)

    Larry W. Burggraf

    2013-07-01

    Full Text Available To find low energy SinCn structures out of hundreds to thousands of isomers we have developed a general method to search for stable isomeric structures that combines Stochastic Potential Surface Search and Pseudopotential Plane-Wave Density Functional Theory Car-Parinello Molecular Dynamics simulated annealing (PSPW-CPMD-SA. We enhanced the Sunders stochastic search method to generate random cluster structures used as seed structures for PSPW-CPMD-SA simulations. This method ensures that each SA simulation samples a different potential surface region to find the regional minimum structure. By iterations of this automated, parallel process on a high performance computer we located hundreds to more than a thousand stable isomers for each SinCn cluster. Among these, five to 10 of the lowest energy isomers were further optimized using B3LYP/cc-pVTZ method. We applied this method to SinCn (n = 4–12 clusters and found the lowest energy structures, most not previously reported. By analyzing the bonding patterns of low energy structures of each SinCn cluster, we observed that carbon segregations tend to form condensed conjugated rings while Si connects to unsaturated bonds at the periphery of the carbon segregation as single atoms or clusters when n is small and when n is large a silicon network spans over the carbon segregation region.

  10. Study of Si-N amorphous compounds combining XPS (X photoemission) and EELS (electron energy loss spectra) optical measurements. Internal levels photoemission. Pt. 2

    International Nuclear Information System (INIS)

    Guraya, M.M.; Acolani, H.; Zampieri, G.E.; Silva, J.H. Dias da; Cisneros, J.I.; Cantao, M.; Marques, F.C.

    1990-01-01

    A Si-N non-stoichiometric hydrogenated amorphous compounds study with different N- contents is presented. The shape and shifts of the photoemission peaks corresponding to the N - 1s and Si - 2p internal levels are analyzed. Based on the latter, the homogeneity of the samples and the Si - N bonds charge transfer is discussed. (Author) [es

  11. The sin in the aetiological concept of Johann Christian August Heinroth (1773-1843). Part 1: Between theology and psychiatry. Heinroth's concepts of 'whose being', 'freedom', 'reason' and 'disturbance of the soul'.

    Science.gov (United States)

    Steinberg, Holger

    2004-09-01

    Throughout his work Johann Christian August Heinroth regarded sin to be the cause of mental illness. The present two-part paper investigates what exactly Heinroth understood by sin. Based on a thorough analysis of his own texts, this study shows that on the one hand Heinroth referred to sin in a Christian-Protestant sense. On the other, however, a moral-ethical code of conduct was also involved. Thus, Heinroth did not regard sin as a singular event, but rather as a life conducted in a wrong way for years or even decades, by which he meant a steady striving towards earthly, bodily satisfaction.

  12. Classicação Sinótica de Frentes Frias Associadas a Chuvas Extremas no Leste de Santa Catarina (SC

    Directory of Open Access Journals (Sweden)

    Gustavo C.J. Escobar

    Full Text Available Resumo O trabalho apresenta uma classificação sinótica de frentes frias sobre o leste do Estado de Santa Catarina (SC, com o propósito de identificar os principais padrões sinóticos associados com chuvas extremas na região do Vale do Itajaí. A metodologia utilizada foi a técnica de Análise de Componentes Principais aplicada à série de reanálises do Climate Forecast System Reanalysis (CFSR (NCEP para o período 1979-2010. Previamente, realiza-se uma climatologia de frentes frias sobre o leste de SC, cujos resultados mostram uma maior frequência de frentes frias associadas a chuvas extremas no Vale do Itajaí durante a primavera. Os resultados fornecem cinco padrões sinóticos principais que representam 83,4% dos casos de frentes frias com chuvas extremas no Vale do Itajaí. O padrão sinótico mais frequente mostra um intenso fluxo de quadrante sudeste sobre a região de estudo, determinado pela presença de um forte anticiclone pós-frontal observado sobre o sul da Província de Buenos Aires, cuja frente fria associada encontra-se no extremo nordeste catarinense. Por último, há dois padrões sinóticos típicos de verão relacionados com chuvas extremas no Vale do Itajaí; um relacionado com episódios de Zona de Convergência do Atlântico Sul (ZCAS e outro associado com a Baixa do Chaco (BCH.

  13. First-principles quantum molecular dynamics study of Ti x Zr1-x N(111)/SiN y heterostructures and comparison with experimental results.

    Science.gov (United States)

    Ivashchenko, Volodymyr; Veprek, Stan; Pogrebnjak, Alexander; Postolnyi, Bogdan

    2014-04-01

    The heterostructures of five monolayers B1-Ti x Zr 1- x N(111), x = 1.0, 0.6, 0.4 and 0.0 (where B1 is a NaCl-type structure) with one monolayer of a Si 3 N 4 -like Si 2 N 3 interfacial layer were investigated by means of first-principles quantum molecular dynamics and a structure optimization procedure using the Quantum ESPRESSO code. Slabs consisting of stoichiometric TiN and ZrN and random, as well as segregated, B1-Ti x Zr 1- x N(111) solutions were considered. The calculations of the B1-Ti x Zr 1- x N solid solutions, as well as of the heterostructures, showed that the pseudo-binary TiN-ZrN system exhibits a miscibility gap. The segregated heterostructures in which Zr atoms surround the Si y N z interface were found to be the most stable. For the Zr-rich heterostructures, the total energy of the random solid solution was lower compared to that of the segregated one, whereas for the Ti-rich heterostructures the opposite tendency was observed. Hard and super hard Zr-Ti-Si-N coatings with thicknesses from 2.8 to 3.5 μ m were obtained using a vacuum arc source with high frequency stimulation. The samples were annealed in a vacuum and in air at 1200 °C. Experimental investigations of Zr-Ti-N, Zr-Ti-Si-N and Ti-Si-N coatings with different Zr, Ti and Si concentrations were carried out for comparison with results obtained from Ti x Zr 1 - x N(111)/SiN y systems. During annealing, the hardness of the best series samples was increased from (39.6 ± 1.4) to 53.6 GPa, which seemed to indicate that a spinodal segregation along grain interfaces was finished. A maximum hardness of 40.8 GPa before and 55 GPa after annealing in air at 500 °C was observed for coatings with a concentration of elements of Si≽ (7-8) at.%, Ti ≽ 22 at.% and Zr ⩽ 70 at.%.

  14. Assessment of heavy metal pollution, spatial distribution and origin in agricultural soils along the Sinú River Basin, Colombia.

    Science.gov (United States)

    Marrugo-Negrete, José; Pinedo-Hernández, José; Díez, Sergi

    2017-04-01

    The presence of metals in agricultural soils from anthropogenic activities such as mining and agricultural use of metals and metal-containing compounds is a potential threat for human health through the food chain. In this study, the concentration of heavy metals in 83 agricultural soils irrigated by the Sinú River, in northern Colombia, affected by mining areas upstream and inundated during seasonal floods events were determined to evaluate their sources and levels of pollution. The average concentrations of Cu, Ni, Pb, Cd, Hg and Zn were 1149, 661, 0.071, 0.040, 0.159 and 1365mg/kg respectively and exceeded the world normal averages, with the exception of Pb and Cd. Moreover, all values surpassed the background levels of soils in the same region. Soil pollution assessment was carried out using contamination factor (CF), enrichment factor (EF), geoaccumulation index (Igeo) and a risk assessment code (RAC). According to these indexes, the soils show a high degree of pollution of Ni and a moderate to high contamination of Zn and Cu; whereas, Pb, Cd and Hg present moderate pollution. However, based on the RAC index, a low environmental risk is found for all the analysed heavy metals. Multivariate statistical analyses, principal component and cluster analyses, suggest that soil contamination was mainly derived from agricultural practices, except for Hg, which was caused probably by atmospheric and river flow transport from upstream gold mining. Finally, high concentrations of Ni indicate a mixed pollution source from agricultural and ferronickel mining activities. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Verificación de las propiedades reológicas del hormigón sin vibrado

    Directory of Open Access Journals (Sweden)

    Gallo, E.

    2004-04-01

    Full Text Available The process of casting is a key issue in the final properties of concrete. The struggle to improve this process has brought the development of a new type of concrete that does not require external vibration in order to fill the formwork. This new type of concrete, known as selfcompacting concrete, differs from other concretes in its rheological properties, but the existing concrete tests does not provide enough information to fully characterize this concrete, either during the design process or the reception at the work place. This work studies some of the proposed validation tests for the fresh state, distinguishing som e advantages and drawbacks among them.

    El proceso de puesta en obra constituye un aspecto clave en las propiedades finales del hormigón. La mejora de este proceso ha desembocado en la aparición de nuevos tipos de hormigón en los que no se necesita vibrado mediante medios mecánicos para rellenar los encofrados. Este tipo de hormigón, conocido como autocompactable, se distingue de otros hormigones por sus propiedades reológicas; pero los actuales ensayos de verificación de las propiedades del hormigón resultan insuficientes para la caracterización completa del hormigón sin vibrado en estado fresco. Este trabajo estudia algunos de los métodos de valoración de propiedades en estado fresco, llegando a distinguir ventajas e inconvenientes de dichos métodos.

  16. Study of Rare B-Meson Decays Related to the CPObservable sin(2beta+gamma) at the BABAR Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Orimoto, Toyoko Jennifer [Univ. of California, Berkeley, CA (United States)

    2006-01-01

    This study reports the observation of the decays B0→D$*+\\atop{s}$π- and B0→D(*)-K+ in a sample of 230 x 106 Y(4S) → B$\\bar{B}$ events collected with the BABAR detector at the PEP-II asymmetric-energy e+e- storage ring, located at the Stanford Linear Accelerator Center. The branching fractions β(B0 → D$+\\atop{S}$π-) = (1.3 ± 0.3 (stat) ± 0.2 (syst)) x 10-5, β(B0 → D$+\\atop{S}$K+) = (2.5 ± 0.4 (stat) ± 0.4 (syst)) x 10-5, β(B0→D$*+\\atop{s}$π-) = (2.8 ± 0.6 (stat) ± 0.5 (syst)) x 10-5, and β(B0→D(*)-K+) = (2.0 ± 0.5 (stat) ± 0.4 (syst)) x 10-5 are measured. The significance of the measurements to differ from zero are 5, 9, 6, and 5 standard deviations, respectively. This is a first observation of the decaysB+→D$*+\\atop{s}$π- and B0→D(*)-K+. These results may potentially be useful in determining the CP asymmetry parameter sin(2β + γ) in the decays B0→D$*+\\atop{s}$π-.

  17. The SINS/zC-SINF survey of z ∼ 2 galaxy kinematics: Evidence for gravitational quenching

    International Nuclear Information System (INIS)

    Genzel, R.; Förster Schreiber, N. M.; Lang, P.; Tacconi, L. J.; Wuyts, S.; Bandara, K.; Burkert, A.; Buschkamp, P.; Davies, R.; Eisenhauer, F.; Kurk, J.; Lutz, D.; Tacchella, S.; Carollo, C. M.; Lilly, S. J.; Cresci, G.; Hicks, E. K. S.; Mancini, C.; Naab, T.; Newman, S.

    2014-01-01

    As part of the SINS/zC-SINF surveys of high-z galaxy kinematics, we derive the radial distributions of Hα surface brightness, stellar mass surface density, and dynamical mass at ∼2 kpc resolution in 19 z ∼ 2 star-forming disks with deep SINFONI adaptive optics spectroscopy at the ESO Very Large Telescope. From these data we infer the radial distribution of the Toomre Q-parameter for these main-sequence star-forming galaxies (SFGs), covering almost two decades of stellar mass (10 9.6 -10 11.5 M ☉ ). In more than half of our SFGs, the Hα distributions cannot be fit by a centrally peaked distribution, such as an exponential, but are better described by a ring, or the combination of a ring and an exponential. At the same time the kinematic data indicate the presence of a mass distribution more centrally concentrated than a single exponential distribution for 5 of the 19 galaxies. The resulting Q-distributions are centrally peaked for all, and significantly exceed unity there for three-quarters of the SFGs. The occurrence of Hα rings and of large nuclear Q-values appears to be more common for the more massive SFGs. While our sample is small and biased to larger SFGs, and there remain uncertainties and caveats, our observations are consistent with a scenario in which cloud fragmentation and global star formation are secularly suppressed in gas-rich high-z disks from the inside out, as the central stellar mass density of the disks grows.

  18. Impacto de las corporaciones y organizaciones sin ánimo de lucro en la gobernabilidad en Medellín

    Directory of Open Access Journals (Sweden)

    Efraín José Martínez Meneses

    2011-07-01

    Full Text Available Resumen:La transferencia del poder que ha venido ocurriendo desde hace 30 años en Medellín y concretamente en sus comunas deprimidas, ha evidenciado el olvido al que sometió el Estado a los barrios estigmatizados por el flagelo del narcotráfico. Es precisamente toda esta organización criminal de los llamados capos de la droga, la que paulatinamente ha venido dejando el poder a la deriva, y la recuperación del mismo se ha realizado con herramientas sociales provenientes de entidades sin ánimo de lucro que a través de programas de ayuda y educación han arrebatado a los aún persistentes carteles del narcotráfico, gran cantidad de miembros y posibles miembros.Palabras clave:Corporación social, derechos humanos, ONG, emprendimiento social, educación.Abstract:The transfer of power has been happening for 30 years in Medellin and specifically in their communes depressed, it became obvious oblivion to which the state submitted to the neighborhoods stigmatized by the scourge of drug trafficking. It is precisely all this criminal organization called drug lords, which have been gradually leaving the power to drift, and its recovery has been made with social tools from nonprofit organizations through programs that help and education have taken the drug cartels still persistent, large numbers of members and potential members.Palabras clave:Corporación social, derechos humanos, ONG, emprendimiento social, educación.

  19. La comprensión verbal y la lectura en niños con y sin retraso lector

    Directory of Open Access Journals (Sweden)

    Luisa Fernanda Bohórquez Montoya

    2014-01-01

    Full Text Available Describir diferencias entre el desempeño en tareas de lectura y de comprensión verbal en niños con y sin retraso lector, así como la relación entre ambos tipos de desempeños. Método. Se utilizaron tareas de lectura de la Evaluación neuropsicológica infantil (ENI y el Índice de Comprensión Verbal (ICV de la escala de inteligencia Wechsler (WISC-IV para niños. Los participantes fueron 40 niños de ambos sexos, entre 7 y 9 años de edad, quienes cursaban entre 2° y 4° grado de primaria en un colegio de estrato socioeconómico bajo de la ciudad de Cali, con un coeficiente intelectual (CI promedio de 86. Los participantes fueron divididos en dos grupos, 20 niños que presentaban retraso lector y 20 niños con un desarrollo lector típico, según los puntajes obtenidos en las tareas de lectura de la ENI. Resultados. Se encontraron diferencias en el rendimiento de ambos grupos de niños evaluados, así como una correlación significativa entre el ICV y el subdominio de comprensión de la ENI. Conclusión. Estos resultados son acordes con la hipótesis de que el desarrollo del lenguaje oral es uno de los principales facilitadores en la adquisición del aprendizaje de la lectura, puesto que en la medida en que el niño comprende la semántica oral, estará con mejor preparación para dotar de significado lo leído.

  20. Comportamiento isohídrico o anisohídrico en vides…. ¿Una controversia sin fin?

    Directory of Open Access Journals (Sweden)

    Hugalde, I. P.

    2014-04-01

    Full Text Available De acuerdo al tipo de respuesta estomática, muchas especies han sido clasificadas como isohídricas o anisohídricas. Las plantas isohídricas son aquellas que cierran sus estomas cuando sensan una caída en el potencial hídrico del suelo, o un aumento en la demanda atmosférica. Al contrario, las plantas anisohídricas no cierran sus estomas y continúan transpirando aun cuando el contenido hídrico del suelo disminuya. Como consecuencia, su potencial hídrico foliar (ΨL cae, y la planta sufre estrés hídrico. En general, se considera que la vid es una planta que evita el estrés hídrico mediante un manejo estomático eficiente. Sin embargo, algunas variedades han mostrado tener un control más estricto que otras. Por esto, algunas variedades pueden ser clasificadas como isohídricas o anisohídricas. Actualmente, esta clasificación se encuentra bajo gran controversia debido a que muchas variedades clasificadas de una manera, mostraron comportamientos opuestos según diferentes situaciones ambientales, climáticas y edáficas. En consecuencia, muchos autores opinan que para variedades de vid esta clasificación no es correcta ni rigurosa. Nuestro estudio pone en revisión, una vez más, el comportamiento de cuatro variedades de vid: (Syrah, Grenache, Malbec y Chardonnay bajo déficit hídrico moderado, tratando de explicar los comportamientos según variables fisiológicas como conductancia estomática (gs, conductancia hidráulica (kH y déficit parcial de vapor (dpv; definiendo qué comportamiento confiere mayor tolerancia a sequía.

  1. DNA–PKcs–SIN1 complexation mediates low-dose X-ray irradiation (LDI)-induced Akt activation and osteoblast differentiation

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Yong; Fang, Shi-ji [The Department of Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou 215000 (China); Zhu, Li-juan [Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases and Institute of Neuroscience, Soochow University, Suzhou, Jiangsu 215021 (China); Zhu, Lun-qing, E-mail: xiaodongwangsz@163.com [The Center of Diagnosis and Treatment for Children’s Bone Diseases, The Children’s Hospital Affiliated to Soochow University, Suzhou, Jiangsu 215000 (China); Zhou, Xiao-zhong, E-mail: zhouxz@suda.edu.cn [The Department of Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou 215000 (China)

    2014-10-24

    Highlights: • LDI increases ALP activity, promotes type I collagen (Col I)/Runx2 mRNA expression. • LDI induces DNA–PKcs activation, which is required for osteoblast differentiation. • Akt activation mediates LDI-induced ALP activity and Col I/Runx2 mRNA increase. • DNA–PKcs–SIN1 complexation mediates LDI-induced Akt Ser-473 phosphorylation. • DNA–PKcs–SIN1 complexation is important for osteoblast differentiation. - Abstract: Low-dose irradiation (LDI) induces osteoblast differentiation, however the underlying mechanisms are not fully understood. In this study, we explored the potential role of DNA-dependent protein kinase catalytic subunit (DNA–PKcs)–Akt signaling in LDI-induced osteoblast differentiation. We confirmed that LDI promoted mouse calvarial osteoblast differentiation, which was detected by increased alkaline phosphatase (ALP) activity as well as mRNA expression of type I collagen (Col I) and runt-related transcription factor 2 (Runx2). In mouse osteoblasts, LDI (1 Gy) induced phosphorylation of DNA–PKcs and Akt (mainly at Ser-473). The kinase inhibitors against DNA–PKcs (NU-7026 and NU-7441) or Akt (LY294002, perifosine and MK-2206), as well as partial depletion of DNA–PKcs or Akt1 by targeted-shRNA, dramatically inhibited LDI-induced Akt activation and mouse osteoblast differentiation. Further, siRNA-knockdown of SIN1, a key component of mTOR complex 2 (mTORC2), also inhibited LDI-induced Akt Ser-473 phosphorylation as well as ALP activity increase and Col I/Runx2 expression in mouse osteoblasts. Co-immunoprecipitation (Co-IP) assay results demonstrated that LDI-induced DNA–PKcs–SIN1 complexation, which was inhibited by NU-7441 or SIN1 siRNA-knockdown in mouse osteoblasts. In summary, our data suggest that DNA–PKcs–SIN1 complexation-mediated Akt activation (Ser-473 phosphorylation) is required for mouse osteoblast differentiation.

  2. Características clínicas y pronóstico a un año de pacientes con síndrome coronario agudo sin elevación del segmento ST y arterias coronarias sanas

    Directory of Open Access Journals (Sweden)

    Nilson López, MD

    2011-11-01

    Conclusiones: La probabilidad de rehospitalización por dolor torácico, necesidad de nueva coronariografía y muerte no difirió entre los pacientes con infarto sin elevación del segmento ST con o sin enfermedad coronaria obstructiva.

  3. 130. Revascularización miocárdica con arterias mamarias internas sin circulación extracorpórea en pacientes octogenarios: experiencia de 5 años

    Directory of Open Access Journals (Sweden)

    M. El Diasty

    2010-01-01

    Conclusiones: En nuestra serie, la técnica de revascularización miocárdica sin CEC y sin manipulación de la aorta ascendente probablemente haya contribuido a reducir los eventos neurológicos permanentes en los pacientes octogenarios.

  4. Comparison of Serum Concentrations of Total Cholesterol and Total ...

    African Journals Online (AJOL)

    Tuberculosis (TB) is one of the most dangerous tropical diseases that complicates HIV infection in Nigeria to date. Over two million Nigerians are known to be infected with TB and many more are at risk of the infection. Serum concentrations of total cholesterol and total lipid of 117 female TB patients attending chest clinic at ...

  5. Changes in total and differential white cell counts, total lymphocyte ...

    African Journals Online (AJOL)

    Background: Published reports on the possible changes in the various immune cell populations, especially the total lymphocyte and CD4 cell counts, during the menstrual cycle in Nigerian female subjects are relatively scarce. Aim: To determine possible changes in the total and differential white blood cell [WBC] counts, ...

  6. The Daya Bay and T2K results on sin2⁡2θ13 and non-standard neutrino interactions

    Directory of Open Access Journals (Sweden)

    I. Girardi

    2014-09-01

    Full Text Available We show that the relatively large best fit value of sin2⁡2θ13=0.14(0.17 measured in the T2K experiment for fixed values of i the Dirac CP violation phase δ=0, and ii the atmospheric neutrino mixing parameters θ23=π/4, |Δm322|=2.4×10−3 eV2, can be reconciled with the Daya Bay result sin2⁡2θ13=0.090±0.009 if the effects of non-standard neutrino interactions (NSI in the relevant ν¯e→ν¯e and νμ→νe oscillation probabilities are taken into account.

  7. Increase in electron mobility of InGaAs/InP composite channel high electron mobility transistor structure due to SiN passivation

    International Nuclear Information System (INIS)

    Liu Yuwei; Wang Hong; Radhakrishnan, K.

    2007-01-01

    The influence of silicon nitride passivation on electron mobility of InGaAs/InP composite channel high electron mobility transistor structure has been studied. Different from the structures with single InGaAs channel, an increase in effective mobility μ e with a negligible change of sheet carrier density n s after SiN deposition is clearly observed in the composite channel structures. The enhancement of μ e could be explained under the framework of electrons transferring from the InP sub-channel into InGaAs channel region due to the energy band bending at the surface region caused by SiN passivation, which is further confirmed by low temperature photoluminescence measurements

  8. EFECTO DE LA DENSIDAD DE PLANTACIÓN EN SANDÍA SIN SEMILLA INJERTADA SOBRE BULE (Lagenaria siceraria (Molina Standl.

    Directory of Open Access Journals (Sweden)

    Jesus Lopez Elias

    2010-11-01

    Full Text Available En los últimos años se ha incrementado el interés en sandía injertada sobre portainjertos tolerantes a Fusarium. En virtud de que la densidad de plantación es un factor determinante en el grado de competencia entre las plantas y de que el rendimiento por planta disminuye a medida que la densidad por unidad de superficie se incrementa, el objetivo de este estudio fue evaluar el efecto de tres densidades de plantación, en hileras a 2.0 m de separación con plantas espaciadas a 1.25, 1.55 y 2.00 m, sobre la producción y calidad de sandía sin semilla híbrido ‘Tri-X 313’, injertada sobre bule (Lagenaria siceraria (Molina Standl. híbrido ‘Emphasis’. El experimento se desarrolló utilizando un diseño en bloques completos al azar, con cuatro repeticiones. Las densidades de plantación evaluadas no influyeron sobre la producción de sandía sin semilla, híbrido ‘Tri-X 313’, injertada sobre L. siceraria; Sin embargo, las plantas injertadas mostraron una disminución del rendimiento por superficie con respecto de aquellas sin injertar, que varió del 10 al 24%, por lo que su uso está restingido a suelos con problemas de estrés causado principalmente por enfermedades. El peso promedio del fruto se incrementó en un 10% con el espaciamiento a 2.00 m. Asimismo, el número de frutos por planta disminuyó significativamente a medida que la densidad se incrementó. Los resultados en sandía injertada no fueron positivos por unidad de superficie; sin embargo, se obtuvo mayor producción por planta a menor densidad de plantación (mayor espaciamiento. Dado el incremento en los costos de producción al utilizar plantas injertadas, existe ventaja en el uso de menor densidad de plantación (mayor espaciamiento, pudiendose usar hasta un 50% menos densidad de plantación que en sandía sin injertar, sin afectar significativamente la producción y la

  9. Caracteristicas de las personas que acuden a las consultas de demanda del centro de salud sin citación previa

    Directory of Open Access Journals (Sweden)

    Pomar Carlos Isanta

    2000-01-01

    Full Text Available FUNDAMENTO: El tiempo de espera para acceder a la consulta está considerado un indicador de satisfacción. Las visitas no urgentes, realizadas sin cita previa, provocan un incremento del tiempo de espera de los pacientes citados, con la consiguiente insatisfacción de los mismos. El objetivo del estudio persigue la valoración cuantitativa de este tipo de visitas y conocer las características de las mismas, para introducir las medidas destinadas a su corrección y racionalización. MÉTODOS: Estudio descriptivo. Se realizó un registro que recogiera las características de los pacientes que originan las consultas sin cita previa, como la edad y el sexo y las relativas a la consulta: motivo, modalidad, jornada laboral y si era realizada de forma directa o indirecta. RESULTADOS: El 14,19% de consultas a demanda no urgentes son sin citación previa. Con el análisis factorial de correspondencias múltiple se identifican dos perfiles de consultas: las directas, solicitadas por pacientes jóvenes, por enfermedad o tareas burocráticas, al final de la consulta de la mañana, estando ellos presentes, y las consultas indirectas, ocasionadas durante las consultas con cita previa por pacientes que solicitan recetas. CONCLUSIONES: Hay un elevado número de visitas sin cita previa. Son precisas medidas que puedan conducir a la utilización del sistema de organización de las consultas y a la mejora de aquellas situaciones que impliquen una falta de accesibilidad, con la finalidad última de mejorar la satisfacción de los usuarios de los servicios sanitarios públicos.

  10. La denuncia de los convenios colectivos sin plazo en el sistema jurídico nacional. Contribuciones para su análisis

    Directory of Open Access Journals (Sweden)

    Eduardo Goldstein

    2014-06-01

    Full Text Available Contenido: Planteo de la temática. ¿De que hablamos cuando expresamos "denuncia" de Convenios Colectivos?. Su noción. Panorama legislativo en los países del MERCOSUR. La expresión unilateral de voluntad de dejar sin efecto una convención. Análisis desde la teoría general del derecho. Denuncia de los Convenios Colectivos. Conclusiones

  11. A Three-Step Atomic Layer Deposition Process for SiN x Using Si2Cl6, CH3NH2, and N2 Plasma.

    Science.gov (United States)

    Ovanesyan, Rafaiel A; Hausmann, Dennis M; Agarwal, Sumit

    2018-06-06

    We report a novel three-step SiN x atomic layer deposition (ALD) process using Si 2 Cl 6 , CH 3 NH 2 , and N 2 plasma. In a two-step process, nonhydrogenated chlorosilanes such as Si 2 Cl 6 with N 2 plasmas lead to poor-quality SiN x films that oxidize rapidly. The intermediate CH 3 NH 2 step was therefore introduced in the ALD cycle to replace the NH 3 plasma step with a N 2 plasma, while using Si 2 Cl 6 as the Si precursor. This three-step process lowers the atomic H content and improves the film conformality on high-aspect-ratio nanostructures as Si-N-Si bonds are formed during a thermal CH 3 NH 2 step in addition to the N 2 plasma step. During ALD, the reactive surface sites were monitored using in situ surface infrared spectroscopy. Our infrared spectra show that, on the post-N 2 plasma-treated SiN x surface, Si 2 Cl 6 reacts primarily with the surface -NH 2 species to form surface -SiCl x ( x = 1, 2, or 3) bonds, which are the reactive sites during the CH 3 NH 2 cycle. In the N 2 plasma step, reactive -NH 2 surface species are created because of the surface H available from the -CH 3 groups. At 400 °C, the SiN x films have a growth per cycle of ∼0.9 Å with ∼12 atomic percent H. The films grown on high-aspect-ratio nanostructures have a conformality of ∼90%.

  12. Therapeutic efficacy of Traditional Chinese medicine, "Kuan-Sin-Yin", in patients undergoing chemotherapy for advanced colon cancer - A controlled trial.

    Science.gov (United States)

    Chien, Tsai-Ju; Liu, Chia-Yu; Lu, Ruey-Hwa; Kuo, Chin-Wei; Lin, Yang-Chao; Hsu, Chung-Hua

    2016-12-01

    Traditional Chinese Medicine (TCM) has been used increasingly as complementary medicine in cancer care. Kuan-Sin-Yin (KSY) is a TCM decoction containing seven herbs known to cause immunomodulation or anticancer activity, and which are associated with the TCM concept of Qi and energy supply. Kuan-Sin-Yin has cytostatic effects on cancer cells in animal models. The aim of this study is to evaluate the level of improvement in meridian energy and heart-rate variability (HRV) and to assess whether these observations are compatible with TCM theory. A non-randomized controlled trial was designed with monitoring of the meridian electro-conductivity and heart-rate variability (HRV) to compare the efficacy of Kuan-Sin-Yin in the control and experimental groups. 52 patients were enrolled in this study. We also measured cancer-related symptoms and quality of life as secondary outcomes. We found that colon cancer patients who received KSY as complementary therapy benefitted with enhancement of meridian energy (Yin meridian: 27.90:35.45μA; p=0.014; Yang meridian: 27.09:33.55μA; p=0.024) and increases in HRV activity (78.40:129.04ms; SDNN: p=0.001) and parasympathetic tone(HF:1644.80:3217.92 ms 2 ; p=0.003; RMMSD:99.76:164.52ms; p=0.002). Cancer-related symptoms decreased (ECOG>1:46.2:7.7%; p=0.0001), and quality of life (KSY group: PCS 35.46:42.12, p=0.0001; MCS: 44.50:47.55, p=0.209) was improved with statistical significance. The correlation of positive results reflected in meridian energy and HRV activity confirms the positive role of complementary medicine of Kuan-Sin-Yin in cancer care. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Análisis de los motivos para la participación en actividades físicas de personas con y sin discapacidad

    OpenAIRE

    Gutiérrez Sanmartín, Melchor; Caus i Pertegáz, Núria

    2006-01-01

    Tradicionalmente, la actividad física adaptada ha sido utilizada para conseguir efectos terapéuticos y rehabilitadores en las personas con discapacidad. Actualmente, los educadores relacionados con la actividad física y deporte adaptado pretenden hacer ver a la sociedad en general que las personas con discapacidad pueden practicar actividades físicas y deportivas por las mismas motivaciones que las personas sin discapacidad. Para contribuir a este objetivo, y empleando como marco de referenci...

  14. Hábitos y técnicas de estudio en adolescentes con trastorno por déficit de atención con o sin hiperactividad

    Directory of Open Access Journals (Sweden)

    María Teresa Iglesias García

    2016-06-01

    Full Text Available Un alto porcentaje de adolescentes con trastorno por déficit de atención con o sin hiperactividad (TDAH no consigue resultados académicamente satisfactorios, debido, entre otras razones, a la poca organización en el estudio y el desconocimiento de técnicas y recursos para abordar las tareas escolares. El objetivo de este trabajo es conocer y mejorar sus hábitos y técnicas de estudio mediante un diseño cuasiexperimental (pretest-aplicación de tratamiento-postest. La muestra resultante estaba formada por 20 estudiantes sin TDAH de distintos cursos de Educación Secundaria Obligatoria (en concreto, 5 de cada curso, y con edades comprendidas entre los 12 y los 16 años y 6 adolescentes con TDAH. El instrumento de evaluación utilizado fue el Inventario de Hábitos de Estudio (Fernández-Pozar, 2002. Entre los resultados encontrados destacamos que los adolescentes con TDAH muestran carencias en todas las escalas del Inventario de Hábitos de Estudio (condiciones ambientales, planificación del estudio, utilización de materiales y asimilación de contenidos, siendo sus puntuaciones significativamente inferiores a las de los adolescentes sin TDAH en cuanto a las condiciones ambientales y mejorando en casi todas las escalas cuando reciben atención educativa especializada.

  15. Total hip arthroplasty in Denmark

    DEFF Research Database (Denmark)

    Pedersen, Alma Becic; Johnsen, Søren Paaske; Overgaard, Søren

    2005-01-01

    The annual number of total hip arthroplasties (THA) has increased in Denmark over the past 15 years. There is, however, limited detailed data available on the incidence of THAs.......The annual number of total hip arthroplasties (THA) has increased in Denmark over the past 15 years. There is, however, limited detailed data available on the incidence of THAs....

  16. Congruences of totally geodesic surfaces

    International Nuclear Information System (INIS)

    Plebanski, J.F.; Rozga, K.

    1989-01-01

    A general theory of congruences of totally geodesic surfaces is presented. In particular their classification, based on the properties of induced affine connections, is provided. In the four-dimensional case canonical forms of the metric tensor admitting congruences of two-dimensional totally geodesic surfaces of rank one are given. Finally, congruences of two-dimensional extremal surfaces are studied. (author)

  17. Propuesta de un plan de mercadeo para el Gimnasio Impacto Total

    OpenAIRE

    Rojas Salazar, Manuel Emilio

    2009-01-01

    Tesis de maestría -- Universidad de Costa Rica. Posgrado en Administración y Dirección de Empresas. Maestría Profesional en Administración y Dirección de Empresas, 2009 El Gimnasio Impacto Total es una micro empresa dedicada a brindar sus servicios en el cantón de Atenas, de nuestro país, donde participa en un mercado bastante competitivo. El gimnasio tiene poco más de un año de haber abierto sus puertas, sin embargo, posee una participación importante en dicho mercado. El presente trabajo...

  18. Arquitectura multi-controlador con transferencia sin salto para procesos con conmutación de modos

    Directory of Open Access Journals (Sweden)

    Nagore Iriondo

    2013-04-01

    Full Text Available Resumen: Los sistemas con conmutación de modos se definen como aquéllos que pueden exhibir diferente comportamiento dinámico en función del estado en que se encuentran. Pueden por tanto ser descritos por un conjunto finito de subsistemas dinámicos y una lógica que rige la conmutación entre ellos. Una alternativa para su control es la arquitectura multi-controlador con supervisión ya que permite utilizar controladores de modo diferentes y alcanzar así múltiples objetivos de control. Pero la conmutación de controladores suele tener como consecuencia la aparición de saltos o transitorios derivados que pueden ser inaceptables. Este tipo de sistemas y problemática son frecuentes en diferentes áreas de aplicación industrial, en donde la tecnología de control más utilizada es el Controlador Lógico Programable (PLC. Es por ello que el objetivo de este trabajo es presentar un método de diseño e implementación de un mecanismo de transferencia sin salto (BT en una arquitectura multi-modo y multi-bucle para sistemas con conmutación de modos, en PLC y en conformidad con el estándar IEC 61131-3. La estrategia BT se basa en que controladores de modos candidatos a conmutar realicen un seguimiento a los controladores activos, siendo la detección del estado de operación actual y de los posibles estados siguientes, clave en la definición de la forma de ejecución de los algoritmos de control que componen la arquitectura. Se presentan también los pasos del diseño de la arquitectura completa así como resultados experimentales que validan la arquitectura. Abstract: Switched mode systems are defined as those represented by a finite set of linear subsystems and a set of logic rules orchestrating the switching among them. A set of dynamic subsystems together with a logical system that orchestrates the switching among them could be used in order to describe it. An alternative to control them is a supervisory multi-mode controller architecture

  19. Totality eclipses of the Sun

    CERN Document Server

    Littmann, Mark; Willcox, Ken

    2008-01-01

    A total eclipse of the Sun is the most awesome sight in the heavens. Totality: Eclipses of the Sun takes you to eclipses of the past, present, and future, and lets you see - and feel - why people travel to the ends of the Earth to observe them. - ;A total eclipse of the Sun is the most awesome sight in the heavens. Totality: Eclipses of the Sun takes you to eclipses of the past, present, and future, and lets you see - and feel - why people travel to the ends of the Earth to observe them. Totality: Eclipses of the Sun is the best guide and reference book on solar eclipses ever written. It explains: how to observe them; how to photograph and videotape them; why they occur; their history and mythology; and future eclipses - when and where to see them. Totality also tells the remarkable story of how eclipses shocked scientists, revealed the workings of the Sun, and made Einstein famous. And the book shares the experiences and advice of many veteran eclipse observers. Totality: Eclipses of the Sun is profusely ill...

  20. Total Product Life Cycle (TPLC)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Total Product Life Cycle (TPLC) database integrates premarket and postmarket data about medical devices. It includes information pulled from CDRH databases...

  1. Nutritional management after total laryngectomy

    African Journals Online (AJOL)

    28 September 2010 with a known diagnosis of cancer of the larynx. The patient, who underwent a total laryngectomy on 13 October, had a tracheostomy inserted .... status, leading to improved quality of life and better response to treatment.4.

  2. Transmandibular approach to total maxillectomy

    OpenAIRE

    Tiwari, R. M.

    2001-01-01

    Total Maxillectomy through transfacial approach has been practiced in the treatment of Cancer for more than a decade. Its role in T3 - T4 tumors extending posteriorly through gthe bony wall is questionable, since an oncological radical procedure is often not possible. Recurrences in the infratemporal fossa are common. Despite the addition of radiotherapy five year survivals have not significantly improved. Transmandibular approach to Total Maxillectomy overcomes this shortcoming by including ...

  3. Leadership and Total Quality Management

    Science.gov (United States)

    1992-04-15

    leadership and management skills yields increased productivity. This paper will focus on the skills required of senior level leaders (leaders at the...publication until it has been cleared by the appropriate mii..-, service or government agency. Leadership and Total Quality Management An Individual Study...llty Codes fAvti1 and/or DltISpecial Abstract AUTHOR: Harry D. Gatanas, LTC, USA TITLE: Leadership and Total Quality Management FORMAT- Individual

  4. Lipoabdominoplastia con cicatriz reducida sin neo-onfaloplastia en abdomen tipo III (Matarasso Short scar lipoabdominoplasty without neoumbilicoplasty in tipe III abdomen (Matarasso

    Directory of Open Access Journals (Sweden)

    P. Centurión

    2009-12-01

    Full Text Available Presentamos una innovadora técnica quirúrgica para el tratamiento de la región abdominal, en la cual combinamos lipoescultura y abdominoplastia con incisiones reducidas, sin neoonfaloplastia, en pacientes tipo III según Clasificación de Matarasso. Realizamos un estudio retrospectivo sobre pacientes intervenidos con esta nueva propuesta quirúrgica, entre los años 2002 y 2008. La lipoescultura corporal superficial y profunda incluyó también la pared abdominal anterior. La técnica quirúrgica se basa en el uso de incisiones reducidas a nivel suprapúbico, máximo de 18 cm. de longitud, con disección de un túnel de aproximadamente 10 cm. en plano supraponeurótico, desinserción del ombligo, plicatura de la diástasis de músculos rectos abdominales y posterior reinserción del ombligo inferiormente. Usamos una férula de yeso durante el postoperatorio. Evaluamos 64 lipoabdominoplastias, todas realizadas en mujeres con edad media de 41,9 años. El tiempo quirúrgico promedio fue de 3 horas y media, el volumen aspirado de la pared abdominal anterior tuvo un promedio de 1000 ml. El 14,1% de las pacientes presentaron seroma como complicación. Como conclusión creemos que esta técnica permite buenos resultados estéticos corporales totales al obtener una cicatriz corta, un colgajo abdominal anterior adelgazado y ausencia de cicatriz umbilical.We present an innovative surgical technique for treatment of abdominal region, in which we combine liposculpture and limited-incisions abdominoplasty without neoumbilicoplasty, in Type III Matarasso Classification patients. We conducted a retrospective study of patients undergoing surgery with this new proposal, between 2002 to 2008. The deep and superficial body liposculpture also included anterior abdominal wall. The surgical technique is based on the use of small incisions at the suprapubic region up to 18 cm long, with dissection of a supraaponeurotical tunnel of 10 cm approximately, with

  5. Multiple embryos in the Lepidocyclina pustulosa group as possible indicators of palaeoenvironmental conditions: The case of the Late Eocene Toluviejo Formation (Sinú Domain, Caribbean, Colombia

    Science.gov (United States)

    Baumgartner-Mora, Claudia; Baumgartner, Peter O.; Rincón Martínez, Daniel; Salazar Ortiz, Edward A.

    2016-04-01

    The Middle-Late Eocene Toluviejo Formation of the Sinú-San Jacinto folded belt (Caribbean, Colombia) contains 15-75 m thick, grey, massive limestone sequences that are interbedded with terrigenous nearshore to offshore mudstones to quartzose sandstones and conglomerates. The formation accumulated in a transitional continent-ocean setting, probably on oceanic crust. We studied over 80 polished thin sections under light microscopy and cathodoluminescence (CL) to analyse carbonate microfacies and Larger Benthic Foraminifera (LBF). The overall facies distribution is 3-fold: (1) Facies close to the shoreline are dominated by low diversity operculinid assemblages, rich in detrital elements. (2) Shallow offshore facies are characterized by round lepidocyclinids, associated with, and often encrusted by, corallinacean algae, Sporolithon and structureless microbial crusts. The matrix is rich in carbonate/detrital mud and sand-sized detritals. (3) Distal offshore facies on structural highs show abundance of flat, current-sorted lepidoclinids without a noticeable detrital component. Facies 1 and 2 are clearly under the influence of suspension- and dissolved-nutrient input, probably carried offshore by freshwater lids of river plumes. Facies (2) contains abundant specimens of the Lepidocyclina pustulosa group of which the macrospheric forms show complicated embryonic apparatuses, which suppose double or multiple embryos. Detailed observation under CL allows to count up to 6-8 embryos, often seen aligned in the equatorial plane. The embryonic apparatus occupies often more than half of the diameter of specimens. The tendency towards large, very flat embryonic apparatuses (diameter measured in axial cuts up to 2,5 mm for a thickness of 0.2-0.3 mm) is closely correlated with abundant coralgal and microbial encrustations, oxide-stained carbonate/detrital mud and probably some preserved organic matter. The presence of multiple embryos has been reported by several authors and has

  6. La solución yodo-yodurada de Lugol endovenosa contra la micosis

    Directory of Open Access Journals (Sweden)

    Manuel José Silva

    1945-05-01

    Full Text Available Como de todos vosotros es sabido el nombre de micosis, se aplica a las enfermedades causadas por hongos microscópicos. Las lesiones que  éstos originan el  hombre, unas veces son internas, y comprometen las vísceras, se localizan  en los músculos, interesan los huesos, atacan las articulaciones; otras, lesionan la piel, en cuyo caso las denominamos  dermatomicosis.

  7. Total body water and total body potassium in anorexia nervosa

    Energy Technology Data Exchange (ETDEWEB)

    Dempsey, D.T.; Crosby, L.O.; Lusk, E.; Oberlander, J.L.; Pertschuk, M.J.; Mullen, J.L.

    1984-08-01

    In the ill hospitalized patient with clinically relevant malnutrition, there is a measurable decrease in the ratio of the total body potassium to total body water (TBK/TBW) and a detectable increase in the ratio of total exchangeable sodium to total exchangeable potassium (Nae/Ke). To evaluate body composition analyses in anorexia nervosa patients with chronic uncomplicated semistarvation, TBK and TBW were measured by whole body K40 counting and deuterium oxide dilution in 10 females with stable anorexia nervosa and 10 age-matched female controls. The ratio of TBK/TBW was significantly (p less than 0.05) higher in anorexia nervosa patients than controls. The close inverse correlation found in published studies between TBK/TBW and Nae/Ke together with our results suggest that in anorexia nervosa, Nae/Ke may be low or normal. A decreased TBK/TBW is not a good indicator of malnutrition in the anorexia nervosa patient. The use of a decreased TBK/TBW ratio or an elevated Nae/Ke ratio as a definition of malnutrition may result in inappropriate nutritional management in the patient with severe nonstressed chronic semistarvation.

  8. Total body water and total body potassium in anorexia nervosa

    International Nuclear Information System (INIS)

    Dempsey, D.T.; Crosby, L.O.; Lusk, E.; Oberlander, J.L.; Pertschuk, M.J.; Mullen, J.L.

    1984-01-01

    In the ill hospitalized patient with clinically relevant malnutrition, there is a measurable decrease in the ratio of the total body potassium to total body water (TBK/TBW) and a detectable increase in the ratio of total exchangeable sodium to total exchangeable potassium (Nae/Ke). To evaluate body composition analyses in anorexia nervosa patients with chronic uncomplicated semistarvation, TBK and TBW were measured by whole body K40 counting and deuterium oxide dilution in 10 females with stable anorexia nervosa and 10 age-matched female controls. The ratio of TBK/TBW was significantly (p less than 0.05) higher in anorexia nervosa patients than controls. The close inverse correlation found in published studies between TBK/TBW and Nae/Ke together with our results suggest that in anorexia nervosa, Nae/Ke may be low or normal. A decreased TBK/TBW is not a good indicator of malnutrition in the anorexia nervosa patient. The use of a decreased TBK/TBW ratio or an elevated Nae/Ke ratio as a definition of malnutrition may result in inappropriate nutritional management in the patient with severe nonstressed chronic semistarvation

  9. Total 2004 annual report; TOTAL 2004 rapport annuel

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This annual report of the Group Total brings information and economic data on the following topics, for the year 2004: the corporate governance, the corporate social responsibility, the shareholder notebook, the management report, the activities, the upstream (exploration and production) and downstream (refining and marketing) operating, chemicals and other matters. (A.L.B.)

  10. Luxación traumática anterior de prótesis total de rodilla

    OpenAIRE

    Hernández Hermoso, José Antonio; Corral Munar, A.; Jimeno Urban, F.

    1998-01-01

    Se presenta un caso de luxación anterior de una prótesis total de rodilla no constreñida que conserva el ligamento cruzado posterior. Su etiopatogenia es diferente a la de las subluxaciones o luxaciones posteriores de prótesis totales de rodilla semiconstreñidas que no conservan el ligamento cruzado posterior. La reducción de la misma se consiguió sin dificultad bajo anestesia general. A pesar de la laxitud residual existente tras el tratamiento conservador, el resultado funcional después de ...

  11. Paschos-Wolfenstein relationship for nuclei and the NuTeV sin2θW measurement

    International Nuclear Information System (INIS)

    Kulagin, S.A.

    2003-01-01

    We discuss the nuclear effects in the Paschos-Wolfenstein relationship in the context of the extraction of the weak mixing angle. We point out that the neutron excess correction to the Paschos-Wolfenstein relationship for a neutron-rich target is negative and large on the scale of the experimental errors of a recent NuTeV measurement. We find a larger neutron excess correction to the Paschos-Wolfenstein relationship for the total cross sections than that discussed by the NuTeV Collaboration. The phenomenological applications of this observation are discussed in the context of the NuTeV deviation. The uncertainties in the neutron excess correction are estimated. The effects due to the Fermi motion, nuclear binding, and nuclear shadowing are also discussed in the context of the total cross sections

  12. Estudio comparativo de la estabilidad lipídica de harinas de soja, sorgo, avena, salvado y germen de trigo con y sin extrusión

    Directory of Open Access Journals (Sweden)

    María José Crosa Balestra

    2013-12-01

    Full Text Available El consumo de harinas de grano entero está condicionado por la pérdida de calidad nutricional, funcional y sensorial durante su almacenamiento. En este estudio se evaluó el efecto del proceso de extrusión en la degradación lipídica de harina de varios tipos de granos y derivados (soja, sorgo, avena, salvado y germen de trigo. Se realizó seguimiento de ácidos grasos libres, humedad, actividad de agua y del desarrollo del descriptor “rancio-oxidado” por olfatación directa, en muestras de harina con y sin extrusión almacenadas durante 60 días en bolsa de polietileno de 30 micrones a 30-35 ºC. También se estudió la aceptabilidad de pan elaborado con 36% de incorporación de una combinación de harinas. Se realizaron medidas de color, materia grasa y actividad ureásica al inicio, medio y final del almacenamiento. Se ajustaron funciones de regresión de la diferencia “sin extrusión” y “con extrusión”, para las medidas AGL, Aw, %H. Los resultados obtenidos indicaron que la extrusión disminuye significativamente la degradación lipídica de las harinas de sorgo, salvado, soja, avena; sin embargo, la harina de germen extrudida tuvo un aumento de rancidez por oxidación. La incorporación de las harinas no extrudidas en la masa de pan disminuyó significativamente la aceptabilidad y afectó la textura y volumen del pan.

  13. High-electric-field-stress-induced degradation of SiN passivated AlGaN/GaN high electron mobility transistors

    International Nuclear Information System (INIS)

    Wen-Ping, Gu; Huan-Tao, Duan; Jin-Yu, Ni; Yue, Hao; Jin-Cheng, Zhang; Qian, Feng; Xiao-Hua, Ma

    2009-01-01

    AlGaN/GaN high electron mobility transistors (HEMTs) are fabricated by employing SiN passivation, this paper investigates the degradation due to the high-electric-field stress. After the stress, a recoverable degradation has been found, consisting of the decrease of saturation drain current I Dsat , maximal transconductance g m , and the positive shift of threshold voltage V TH at high drain-source voltage V DS . The high-electric-field stress degrades the electric characteristics of AlGaN/GaN HEMTs because the high field increases the electron trapping at the surface and in AlGaN barrier layer. The SiN passivation of AlGaN/GaN HEMTs decreases the surface trapping and 2DEG depletion a little during the high-electric-field stress. After the hot carrier stress with V DS = 20 V and V GS = 0 V applied to the device for 10 4 sec, the SiN passivation decreases the stress-induced degradation of I Dsat from 36% to 30%. Both on-state and pulse-state stresses produce comparative decrease of I Dsat , which shows that although the passivation is effective in suppressing electron trapping in surface states, it does not protect the device from high-electric-field degradation in nature. So passivation in conjunction with other technological solutions like cap layer, prepassivation surface treatments, or field-plate gate to weaken high-electric-field degradation should be adopted. (condensed matter: electronic structure, electrical, magnetic, and optical properties)

  14. Design and Implementation WebGIS for Improving the Quality of Exploration Decisions at Sin-Quyen Copper Mine, Northern Vietnam

    Science.gov (United States)

    Quang Truong, Xuan; Luan Truong, Xuan; Nguyen, Tuan Anh; Nguyen, Dinh Tuan; Cong Nguyen, Chi

    2017-12-01

    The objective of this study is to design and implement a WebGIS Decision Support System (WDSS) for reducing uncertainty and supporting to improve the quality of exploration decisions in the Sin-Quyen copper mine, northern Vietnam. The main distinctive feature of the Sin-Quyen deposit is an unusual composition of ores. Computer and software applied to the exploration problem have had a significant impact on the exploration process over the past 25 years, but up until now, no online system has been undertaken. The system was completely built on open source technology and the Open Geospatial Consortium Web Services (OWS). The input data includes remote sensing (RS), Geographical Information System (GIS) and data from drillhole explorations, the drillhole exploration data sets were designed as a geodatabase and stored in PostgreSQL. The WDSS must be able to processed exploration data and support users to access 2-dimensional (2D) or 3-dimensional (3D) cross-sections and map of boreholles exploration data and drill holes. The interface was designed in order to interact with based maps (e.g., Digital Elevation Model, Google Map, OpenStreetMap) and thematic maps (e.g., land use and land cover, administrative map, drillholes exploration map), and to provide GIS functions (such as creating a new map, updating an existing map, querying and statistical charts). In addition, the system provides geological cross-sections of ore bodies based on Inverse Distance Weighting (IDW), nearest neighbour interpolation and Kriging methods (e.g., Simple Kriging, Ordinary Kriging, Indicator Kriging and CoKriging). The results based on data available indicate that the best estimation method (of 23 borehole exploration data sets) for estimating geological cross-sections of ore bodies in Sin-Quyen copper mine is Ordinary Kriging. The WDSS could provide useful information to improve drilling efficiency in mineral exploration and for management decision making.

  15. Calidad total en el ICESI

    OpenAIRE

    González Zamora, José Hipólito

    2010-01-01

    En primer lugar deseo dar la bienvenida esta reunión al ingeniero Francisco Gensini, director ejecutivo de INCOLDA, quien ha sido fuente constante de inspiración para el trabajo relacionado con Control Total de Calidad (C.T.C.) que se ha venido desarrollando en el ICESI. El ingeniero Gensini ha logrado aglutinar alrededor de INCOLDA al grupo de seis empresas de la región, líderes en el estudio y aplicación de los principios del Control Total de Calidad , es decir Rica Rondo S.A., Banco de Oc...

  16. Relación del perfil salival con el grado de inmunosupresión en pacientes infectados con VIH con y sin tratamiento antirretroviral

    OpenAIRE

    Vera Cruz, Moisés; Cornejo Salaza, José; Chiyong, Teresa Evaristo; Arevalo Abanto, Jorge A.; Villanueva Vílchez, Hugo G.

    2014-01-01

    El objetivo del estudio fue evaluar el perfil salival de pacientes con infección por VIH con y sin Tratamiento Antirretroviral de Gran Actividad (TARGA), por medio de la evaluación de los síntomas de hipofunción salival (Xerostomía, Disgeusia, Disfagia y Susceptibilidad de desarrollar úlceras orales), la Tasa de Flujo salival no estimulado, el pH salival y la viscosidad salival; estableciendo su relación con el Grado de Inmunosupresión, evaluado por medio del Recuento de Linfocitos CD4/μl. Se...

  17. Método para la obtención de cultivares de tomate con frutos partenocárpicos (sin semillas) y mayor calidad organoléptica

    OpenAIRE

    Ellul, Philippe; Angosto Trillo, Trinidad; García-Sogo, Begoña; Martín Trillo, Mar; Martínez-Zapater, José M.; Lozano Ruiz, Rafael; Moreno Ferrero, Vicente

    2005-01-01

    Método para la obtención de cultivares de tomate con frutos partenocárpicos (sin semillas) y mayor calidad organoléptica. El método se basa en la transferencia y expresión del gen LFY de Arabidopsis thaliana en plantas transgénicas de tomate. Los frutos de las plantas transgénicas con el gen LFY mantienen el mismo tamaño y peso que los del cultivar original, pero carecen de semillas, tienen más carne, menos pulpa y una forma ligeramente apuntillada. El análisis de cali...

  18. Identificación de Arcobacter en heces de niños y adultos con/sin diarrea y en reservorios animales

    OpenAIRE

    Rito Zerpa Larrauri; Jorge O Alarcón Villaverde; Percy E Lezama Vigo; Lilian Patiño Gabriel; Alberto Reyes Dioses; Augusto M Valencia Ramírez; Jorge Velásquez; Carlos R Sevilla Andrade; Miriam J Alarcón León

    2014-01-01

    Introducción: Los microorganismos del género Arcobacter, considerados patógenos zoonóticos emergentes, son morfológicamente similares a Campylobacter. Los reportes de Arcobacter como agente etiológico de diarrea en humanos en América Latina son escasos. En el Perú no se ha comunicado su aislamiento en heces de humanos o en animales. Objetivos: Conocer la prevalencia de Arcobacter en heces de niños y adultos con/sin diarrea y en animales: aves, ganado vacuno, porcino, peces y mariscos. Diseño:...

  19. ¿Cómo realizar elecciones inauténticas sin morir en el intento? El caso de México y su sistema electoral

    OpenAIRE

    Cansino, César

    2012-01-01

    Si hay un caso en el mundo que por sí solo haya implementado y perfeccionado todas las modalidades posibles e imposibles de elecciones inauténticas, ese caso es sin duda México. Parte de la explicación de ello se encuentra en el sistema electoral mexicano, diseñado para que reine la discrecionalidad sobre el imperio de la ley. En este estudio se analiza el fenómeno con los fallos que al cobijo de la ley realizó el Tribunal Electoral del Poder Judicial de la Federación en ocasión de los comici...

  20. A census study exploring the training needs of nurses working in Kwong Wah Hospital and Wong Tai Sin Hospital in Hong Kong, China.

    Science.gov (United States)

    Lai, Yuk-Wah

    2013-01-01

    As part of the strategic professional development plan for nurses, training needs analysis was conducted from August 2011 to February 2012, in the form of descriptive research with survey design. The aim was to support nursing staff in their professional development needs and promote staff engagement. Consecutive sampling was employed; all full time nurses working in Kwong Wah Hospital (KWH) and Wong Tai Sin Hospital (WTSH) were recruited and invited to complete a self-administered questionnaire. Based on the findings and conclusions, follow up strategies were proposed. Management then built a sustainable learning environment for KWH and WTSH nurses in the 2012-2015 professional development plan.

  1. Contribución del marketing social a la sostenibilidad de fundaciones sin ánimo de lucro: un estudio de caso

    OpenAIRE

    Pinilla Peña, Maricela

    2011-01-01

    El propósito de la presente investigación es aproximarse al conocimiento de las fundaciones, entidades sin ánimo de lucro, determinar sus características, procesos administrativos y de marketing que éstas implementan, para hacer frente a la provisión de productos y servicios sociales a través del despliegue del denominado marketing social / Abstract: The purpose of this research is to approach the knowledge of foundations, nonprofit organizations, identify their characteristics, administrativ...

  2. Análisis de resultados de entrevistas a jóvenes universitarios sin hijos sobre representaciones sociales de maternidad y paternidad

    OpenAIRE

    Feldman, Graciela Noemi; González, Angel; Iglesias, Soledad; Colombo, María Elena; D'Avirro, María Julieta

    2009-01-01

    Este informe es parte de un proyecto de investigación trienal que se plantea la exploración de las representaciones sociales –RRSS- de la maternidad y de la paternidad en adolescentes tardíos universitarios sin hijos. Las RRSS son una construcción sociocultural (Wagner & Elejabarrieta, 1994), cuyos contenidos emergen de procesos sociales, que a su vez influyen sobre la realidad. Las RRSS se refieren a imágenes y modelos que explican algún fenómeno relevante para un grupo social determinado (A...

  3. Ileana Diéguez. 'Cuerpos sin duelo. Iconografía y teatralidad del dolor'. Córdoba (Arg.): Ediciones DocumentA/Escénicas, 2013.

    OpenAIRE

    Tatiana Bubnova

    2016-01-01

    Cuerpos sin duelo. Iconografía y teatralidad del dolor es un libro estupendamente escrito y académicamente riguroso. Al mismo tiempo es un libro abominable. Lo es porque trata de una manera anatómica, al mismo tiempo que inquietante y reflexiva, aquello que todos sabemos que existe, pero no queremos enterarnos. La cuestión de la estética y del arte actual también es una línea magistral de este libro, problema que se replantea de una manera radical.

  4. Efecto de la adición de polioles sobre la calidad de bizcochos sin gluten, cocinados en horno convencional y en microondas

    OpenAIRE

    Rodríguez Pérez, María

    2013-01-01

    La diabetes es una enfermedad que está impulsando la demanda de nuevos productos con menos azúcar y calorías. Por otra parte, existe una asociación bien conocida entre la enfermedad celiaca y la diabetes mellitus tipo 1, debiéndose también excluir en la dieta de este colectivo los alimentos con gluten. En la mayoría de los productos, sin embargo, la eliminación o reducción de ingredientes o componentes de sus materias primas provoca pérdidas fácilmente detectables en la apariencia, textura y ...

  5. Measurement of the CP Violating Phase $\\boldsymbol{\\sin(2\\beta_{s})}$ using $\\boldsymbol{B^{0}_{s}\\rightarrow J/\\psi\\phi}$ Decays at CDF

    Energy Technology Data Exchange (ETDEWEB)

    Pueschel, Elisa [Carnegie Mellon Univ., Pittsburgh, PA (United States)

    2010-05-01

    A B0 s meson can oscillate into its anti-particle, the $\\bar{B}$0 s meson, before decaying. CP violation in this system is made possible by the presence of amplitudes from both mixed and unmixed B0 s meson decays. The CP violating phase βs appears in the interference between the decay amplitudes. The quantity sin(2βs) is expected to be small in the standard model. Thus, measuring a large value for sin(2βs) would be an unequivocal sign of new physics participation in the B0 s mixing loop diagram. In this thesis, we present a latest measurement of sin(2βs), using 5.2 fb-1 of data collected at CDF from p$\\bar{p}$ collisions at a center of mass energy of √s=1.96 TeV. A time-dependent angular analysis, with the production flavor of the B0 s meson identified with flavor tagging methods, is used to extract sin(2βs) from ~6500 B0 s→ J/ψφ decays. Other parameters of interest, such as the B0 s lifetime and the decay width difference between the heavy and light B0 s mass eigenstates are determined to high precision. Also, the effect of potential contributions to the final state from B0 s → J/ψf0 and B0 s→ J/ψK+K- decays is considered for the first time. We present 68% and 95% confidence regions in the βs plane. The probability that the observed central value is a fluctuation of the data from the standard model expected value of βs is calculated to be 44%. The observed confidence region shows better agreement with the standard model prediction than previous measurements.

  6. Sinéresis, características reológicas y consistencia sensorial de salsa de alcachofa (Cynara scolymus L.

    Directory of Open Access Journals (Sweden)

    Francisco Mora Barandiarán

    2013-01-01

    Full Text Available Se investigó el efecto de la concentración de tres hidrocoloides: CMC, goma guar y goma xantana, y sus mezclas en la sinéresis, características reológicas y consistencia sensorial de salsa de alcachofa (Cynara scolymus L. variedad Imperial Star. La sinéresis se determinó mediante la pérdida de agua por centrifugación; las características reológicas de la salsa de alcachofa utilizando un reómetro marca Brookfield modelo RVDV – III y finalmente, la consistencia sensorial, mediante una escala hedónica de nueve puntos. Se aplicó un diseño de mezclas simplex reticular con centroide ampliado bajo la metodología de superficie de respuesta para establecer el efecto de la concentración de hidrocoloides sobre la sinéresis, características reológicas y consistencia sensorial. En todos los tratamientos, la viscosidad aparente disminuyó con la velocidad de cizalla demostrando un comportamiento “no newtoniano” de tipo “plástico general” con un valor “n” menor a 1 y un esfuerzo de corte inicial. El índice reológico estuvo en el rango de 0,0856 y 0,3131 (n < 1, el índice de consistencia “k” en el rango de 84,55 y 167,80 Pa.sn, esfuerzo de corte inicial en el rango de 9,10 y 13,51Pa y la consistencia sensorial presentó calificaciones de “me gusta” a “me gusta ligeramente”. Finalmente, se optimizó la mezcla de hidrocoloides sobre la zona de formulación factible. Con la mezcla óptima, correspondiente a: 0,28% CMC; 0,13% goma guar y 0,59% goma xantana se espera obtener una sinéresis de 0,089% y una calificación de 6 “me gusta ligeramente” en cuanto a la consistencia sensorial.

  7. Angústia hipocondríaca e o eterno retorno do presente: considerações a partir do filme Sinédoque, New York

    OpenAIRE

    Klein, Thaís; Herzog, Regina

    2017-01-01

    Resumo A partir de questionamentos levantados pelo filme Sinédoque, New York (2008), pretende-se discutir a articulação da angústia hipocondríaca com a temporalidade. Observa-se que no filme o recurso do flashback não é utilizado; a temporalidade, que se instaura diante da angústia relacionada a sintomas hipocondríacos do personagem, calca-se em um presente absoluto. A hipocondria foi considerada por Freud uma neurose atual e a angústia a ela articulada opera como a contrapartida afetiva do e...

  8. La cadera luxable del recién nacido que sin tratamiento se estabiliza pronto, ¿es patológica o no?

    Directory of Open Access Journals (Sweden)

    Néctar León Daza V.

    2007-01-01

    Full Text Available En textos de consulta y artículos publicados en revistas médicas de prestigio sobre la enfermedad conocida hoy como Displasia del Desarrollo de la Cadera (DDC, se afirma que la cadera que se halló luxable al primer examen del recién nacido, y que, sin tratamiento, se encontró estable al segundo examen realizado dos semanas después, curó espontáneamente. En este artículo se presentan evidencias y argumentos que demuestran que esa luxabilidad articular, aunque desaparezca en 24 horas, indica que existe daño estructural.

  9. Extracción y reología de Betaglucanos de cebada y elaboración de masas de pan sin gluten enriquecidas con los extractos

    OpenAIRE

    Rivero Hernández, Miguel

    2012-01-01

    La materia prima utilizada ha sido la cebada H13 tipo waxy, una cebada desnuda, es decir sin cáscara, con un contenido de beta-glucanos del 4,51%, de la que se obtuvieron tres extractos distintos: el primero procedente de la harina integral de la cebada (18,8 % de -glucanos), el segundo de esa misma harina integral tratada con etanol para inactivar las betaglucanasas (21,5 % de -glucanos), y el tercero procedente de la fracción gruesa de la molienda pretratada igualmente con ...

  10. Total phenolics and total flavonoids in selected Indian medicinal plants.

    Science.gov (United States)

    Sulaiman, C T; Balachandran, Indira

    2012-05-01

    Plant phenolics and flavonoids have a powerful biological activity, which outlines the necessity of their determination. The phenolics and flavonoids content of 20 medicinal plants were determined in the present investigation. The phenolic content was determined by using Folin-Ciocalteu assay. The total flavonoids were measured spectrophotometrically by using the aluminium chloride colorimetric assay. The results showed that the family Mimosaceae is the richest source of phenolics, (Acacia nilotica: 80.63 mg gallic acid equivalents, Acacia catechu 78.12 mg gallic acid equivalents, Albizia lebbeck 66.23 mg gallic acid equivalents). The highest total flavonoid content was revealed in Senna tora which belongs to the family Caesalpiniaceae. The present study also shows the ratio of flavonoids to the phenolics in each sample for their specificity.

  11. Total Synthesis of Adunctin B.

    Science.gov (United States)

    Dethe, Dattatraya H; Dherange, Balu D

    2018-03-16

    Total synthesis of (±)-adunctin B, a natural product isolated from Piper aduncum (Piperaceae), has been achieved using two different strategies, in seven and three steps. The efficient approach features highly atom economical and diastereoselective Friedel-Crafts acylation, alkylation reaction and palladium catalyzed Wacker type oxidative cyclization.

  12. Edge colouring by total labellings

    DEFF Research Database (Denmark)

    Brandt, Stephan; Rautenbach, D.; Stiebitz, M.

    2010-01-01

    We introduce the concept of an edge-colouring total k-labelling. This is a labelling of the vertices and the edges of a graph G with labels 1, 2, ..., k such that the weights of the edges define a proper edge colouring of G. Here the weight of an edge is the sum of its label and the labels of its...

  13. What is Total Quality Management?

    Science.gov (United States)

    Bryan, William A.

    1996-01-01

    Provides a general overview of Total Quality Management (TQM) and explains why there is pressure for change in higher education institutions. Defines TQM and the various themes, tools, and beliefs that make it different from other management approaches. Presents 14 principles and how they might be applied to student affairs. (RJM)

  14. A totally diverting loop colostomy.

    Science.gov (United States)

    Merrett, N. D.; Gartell, P. C.

    1993-01-01

    A technique is described where the distal limb of a loop colostomy is tied with nylon or polydioxanone. This ensures total faecal diversion and dispenses with the supporting rod, enabling early application of stoma appliances. The technique does not interfere with the traditional transverse closure of a loop colostomy. PMID:8379632

  15. A generalization of total graphs

    Indian Academy of Sciences (India)

    M Afkhami

    2018-04-12

    Apr 12, 2018 ... product of any lower triangular matrix with the transpose of any element of U belongs to U. The ... total graph of R, which is denoted by T( (R)), is a simple graph with all elements of R as vertices, and ...... [9] Badawi A, On dot-product graph of a commutative ring, Communications in Algebra 43 (2015). 43–50.

  16. Total synthesis of nepetoidin B

    Science.gov (United States)

    The total synthesis of nepetoidin B (the 2-(3,4-dihydroxyphenyl)ethenyl ester of 3-(3,4-dihydroxy¬phenyl)-2-propenoic acid) has been achieved in two steps from commercially available 1,5-bis(3,4-dimethoxyphenyl)-1,4-pentadien-3-one. Tetramethylated nepetoidin B was prepared directly by Baeyer-Villig...

  17. The "Total Immersion" Meeting Environment.

    Science.gov (United States)

    Finkel, Coleman

    1980-01-01

    The designing of intelligently planned meeting facilities can aid management communication and learning. The author examines the psychology of meeting attendance; architectural considerations (lighting, windows, color, etc.); design elements and learning modes (furniture, walls, audiovisuals, materials); and the idea of "total immersion meeting…

  18. First total synthesis of Boehmenan

    Indian Academy of Sciences (India)

    The first total synthesis of dilignan Boehmenan has been achieved. A biomimetic oxidative coupling of the ferulic acid methyl ester in the presence of silver oxide is the crucial step in the synthesis sequence, generating the dihydrobenzofuran skeleton. Hydroxyl group was protected with DHP and reducted with LiAlH4 to ...

  19. MODIFIED TECHNIQUE OF TOTAL LARYNGECTOMY

    Directory of Open Access Journals (Sweden)

    Predrag Spirić

    2010-12-01

    Full Text Available Surgical technique of total laryngectomy is well presented in many surgical textbooks. Essentially, it has remained the same since Gluck an Soerensen in 1922 described all its details. Generally, it stresses the U shape skin incision with releasing laryngeal structures and removing larynx from up to down. Further, pharyngeal reconstruction is performed with different kinds of sutures in two or more layers and is finished with skin suture and suction drainage. One of worst complications following this surgery is pharyngocutaneous fistula (PF. Modifications proposed in this this article suggests vertical skin incision with larynx removal from below upwards. In pharyngeal reconstruction we used the running locked suture in submucosal plan with „tobacco sac“ at the end on the tongue base instead of traditional T shaped suture. Suction drains were not used.The aim of study was to present the modified surgical technique of total laryingectomy and its impact on hospital stay duration and pharyngocutanous fistula formation. In this randomized study we analyzed 49 patients operated with modified surgical technique compared to 49 patient operated with traditional surgical technique of total laryngectomy. The modified technique of total laryngectomy was presented. Using modified technique we managed to decrease the PF percentage from previous 20,41% to acceptable 8,16% (p=0,0334. Also, the average hospital stay was shortened from 14,96 to 10,63 days (t =-2.9850; p=0.0358.The modified technique of total laryngectomy is safe, short and efficient surgical intervention which decreases the number of pharyngocutaneos fistulas and shortens the hospital stay.

  20. Estudio exploratorio de la oferta de bebidas sin alcohol en comercios mayoristas y minoristas de ciudad de La Plata

    OpenAIRE

    Papalardo, Brenda; García, Silvia; Prestes, Mariana; Fasano, María Victoria; Olmedo, Luciana; Henning, María Florencia; Malpeli, Agustina; Bisceglia, María Gabriela; Pellón Maisón, Magalí

    2017-01-01

    Los hábitos de consumo alimentario actuales promueven el sobrepeso y la obesidad. Se consiguen alimentos a menores precios, particularmente aquellos con una alta densidad energética y con mayor grado de procesamiento, como las bebidas endulzadas con edulcorantes calóricos. La Argentina se posiciona como uno de los líderes del mercado y como uno de los mayores consumidores a nivel mundial de este tipo de bebidas. Los objetivos de este trabajo fueron: -Explorar el contenido total de hidra...

  1. Efectividad del tratamiento mediante ultrasonido y ejercicios terapéuticos en la tendinitis del supraespinoso sin calcificar

    OpenAIRE

    Vírseda García, Ángela

    2011-01-01

    Introducción: La tendinitis del músculo supraespinoso en una de las causas más frecuentes de consulta en Atención Primaria. En el caso del Centro de Salud Daroca supone un 43,80 % del total de patologías de hombro. Debido a la frecuencia de dicha patología y a la repercusión de la misma es necesario presentar un método de tratamiento lo más efectivo posible. Objetivo: Comprobar la efectividad del tratamiento fisioterapéutico combinado de ultrasonido y ejercicios terapéuticos en pacientes ...

  2. Subtotal versus total abdominal hysterectomy

    DEFF Research Database (Denmark)

    Andersen, Lea Laird; Ottesen, Bent; Alling Møller, Lars Mikael

    2015-01-01

    OBJECTIVE: The objective of the study was to compare long-term results of subtotal vs total abdominal hysterectomy for benign uterine diseases 14 years after hysterectomy, with urinary incontinence as the primary outcome measure. STUDY DESIGN: This was a long-term follow-up of a multicenter......, randomized clinical trial without blinding. Eleven gynecological departments in Denmark contributed participants to the trial. Women referred for benign uterine diseases who did not have contraindications to subtotal abdominal hysterectomy were randomized to subtotal (n = 161) vs total (n = 158) abdominal...... from discharge summaries from all public hospitals in Denmark. The results were analyzed as intention to treat and per protocol. Possible bias caused by missing data was handled by multiple imputation. The primary outcome was urinary incontinence; the secondary outcomes were pelvic organ prolapse...

  3. Evaluaciones externas sin retroalimentación pedagógica: las escuelas estarán siempre en el mismo lugar

    Directory of Open Access Journals (Sweden)

    Fabio Jurado Valencia

    2015-02-01

    Full Text Available Entre los años 2012 y 2013 el Grupo de Investigación en Evaluación desarrolló un proyecto en torno a las condiciones infraestructurales y pedagógicas de una muestra de escuelas de zonas periféricas, habitadas por comunidades afrodescendientes e indígenas, a partir de los resultados del Segundo Estudio Regional Comparativo y Explicativo de la Calidad de la Educación en América Latina y el Caribe. La investigación confirmó los rezagos en la formación de los docentes y la ausencia de textos para leer de diverso género, sin los cuales, concluye el estudio, es imposible lograr que la escuela eduque en la lectura crítica y en el diálogo con los saberes que requieren los ciudadanos. Sin embargo, la investigación muestra también que el liderazgo de la dirección escolar y el empeño intelectual de algunos maestros puede romper con la desesperanza e incrementar la calidad de los aprendizajes de los estudiantes.

  4. Epigenetic Silencing of the Proapoptotic Gene BIM in Anaplastic Large Cell Lymphoma through an MeCP2/SIN3a Deacetylating Complex

    Directory of Open Access Journals (Sweden)

    Rocco Piazza

    2013-05-01

    Full Text Available BIM is a proapoptotic member of the Bcl-2 family. Here, we investigated the epigenetic status of the BIM locus in NPM/ALK+ anaplastic large cell lymphoma (ALCL cell lines and in lymph node biopsies from NPM/ALK+ ALCL patients. We show that BIM is epigenetically silenced in cell lines and lymph node specimens and that treatment with the deacetylase inhibitor trichostatin A restores the histone acetylation, strongly upregulates BIM expression, and induces cell death. BIM silencing occurs through recruitment of MeCP2 and the SIN3a/histone deacetylase 1/2 (HDAC1/2 corepressor complex. This event requires BIM CpG methylation/demethylation with 5-azacytidine that leads to detachment of the MeCP2 corepressor complex and reacetylation of the histone tails. Treatment with the ALK inhibitor PF2341066 or with an inducible shRNA targeting NPM/ALK does not restore BIM locus reacetylation; however, enforced expression of NPM/ALK in an NPM/ALK-negative cell line significantly increases the methylation at the BIM locus. This study demonstrates that BIM is epigenetically silenced in NPM/ALK-positive cells through recruitment of the SIN3a/HDAC1/2 corepressor complex and that NPM/ALK is dispensable to maintain BIM epigenetic silencing but is able to act as an inducer of BIM methylation.

  5. Índices de ruido urbano en el día sin carro en la ciudad de Medellín

    Directory of Open Access Journals (Sweden)

    Jeiser Rendón

    2010-12-01

    Full Text Available Con el presente artículo se pretende descubrir, a través de mediciones de ruido ambiental y datos de flujo vehicular, el cambio del paisaje sonoro en la ciudad de Medellín durante la implementación del día sin carro del día jueves 22 de abril de 2010; para lo que se tuvo como referencia cuatro puntos significativos de la ciudad: Monterrey, Alpujarra, Avenida Ferrocarril y la calle 33. Para el proceso de adquisición de datos se realizaron mediciones, tanto en el día sin carro, como en un día con carro, teniendo como fundamento la Resolución 0627 de 2006 “Mediante la cual, se establece la norma nacional de emisión de ruido y ruido ambiental” y la ISO 1996 “Norma internacional que contiene la descripción, medición y la evaluación de ruido ambiental”. Fue importante en esta investigación constatar la incidencia de los automóviles particulares en los niveles de ruido urbano que posee la ciudad, analizando las mediciones obtenidas este día, y encontrando congruencias funcionales entre el ruido urbano y los automóviles.

  6. Properties of superconducting S-I-N, S-I-S, and S-C-S structures with amorphous weak coupling

    International Nuclear Information System (INIS)

    Kozub, V.I.

    1984-01-01

    The properties due to the presence of two-level structure systems in superconducting tunnel junctions with amorphous insulators, as well as in point and bridge Josephson junctions with amorphous surrounds, are investigated. Equations are obtained for tunneling with participation of the two-level systems for the cases of quasistatic tunneling in an S-I-N junction (N is the normal metal) and for the case of Josephson tunneling in an S-I-S junction. It is shown that inelastic tunneling makes an additional contribution to the nonlinearity of the current-voltage characteristic of an S-I-N junction. The specific phenomena of nonexponential relaxation in this junction (in particular, tunnel-current relaxation), which have a 1/t dependence, are discussed. Low-frequency noise in S-I-S and S-C-S structures, due to transitions in the two-level system and having a 1/f dependence at not too small junction sizes are considered. In the case of the stationary Josephson effect this noise has features of critical-current fluctuations that can manifest themselves, in particular as fluctuations of the magnetic flux linked with a weakly coupled superconducting ring. Under conditions of the nonstationary Josephson effect the two-level structures lead to broadening of the Josephson-generation line. It is proposed to use the nonstationary Josephson effect to observe the echo effect in glasses

  7. Measurement of sin2θefflept using e+e- pairs from γ*/Z bosons produced in p p ¯ collisions at a center-of-momentum energy of 1.96 TeV

    Science.gov (United States)

    Aaltonen, T.; Amerio, S.; Amidei, D.; Anastassov, A.; Annovi, A.; Antos, J.; Apollinari, G.; Appel, J. A.; Arisawa, T.; Artikov, A.; Asaadi, J.; Ashmanskas, W.; Auerbach, B.; Aurisano, A.; Azfar, F.; Badgett, W.; Bae, T.; Barbaro-Galtieri, A.; Barnes, V. E.; Barnett, B. A.; Barria, P.; Bartos, P.; Bauce, M.; Bedeschi, F.; Behari, S.; Bellettini, G.; Bellinger, J.; Benjamin, D.; Beretvas, A.; Bhatti, A.; Bland, K. R.; Blumenfeld, B.; Bocci, A.; Bodek, A.; Bortoletto, D.; Boudreau, J.; Boveia, A.; Brigliadori, L.; Bromberg, C.; Brucken, E.; Budagov, J.; Budd, H. S.; Burkett, K.; Busetto, G.; Bussey, P.; Butti, P.; Buzatu, A.; Calamba, A.; Camarda, S.; Campanelli, M.; Canelli, F.; Carls, B.; Carlsmith, D.; Carosi, R.; Carrillo, S.; Casal, B.; Casarsa, M.; Castro, A.; Catastini, P.; Cauz, D.; Cavaliere, V.; Cerri, A.; Cerrito, L.; Chen, Y. C.; Chertok, M.; Chiarelli, G.; Chlachidze, G.; Cho, K.; Chokheli, D.; Clark, A.; Clarke, C.; Convery, M. E.; Conway, J.; Corbo, M.; Cordelli, M.; Cox, C. A.; Cox, D. J.; Cremonesi, M.; Cruz, D.; Cuevas, J.; Culbertson, R.; d'Ascenzo, N.; Datta, M.; de Barbaro, P.; Demortier, L.; Deninno, M.; D'Errico, M.; Devoto, F.; Di Canto, A.; Di Ruzza, B.; Dittmann, J. R.; Donati, S.; D'Onofrio, M.; Dorigo, M.; Driutti, A.; Ebina, K.; Edgar, R.; Erbacher, R.; Errede, S.; Esham, B.; Farrington, S.; Fernández Ramos, J. P.; Field, R.; Flanagan, G.; Forrest, R.; Franklin, M.; Freeman, J. C.; Frisch, H.; Funakoshi, Y.; Galloni, C.; Garfinkel, A. F.; Garosi, P.; Gerberich, H.; Gerchtein, E.; Giagu, S.; Giakoumopoulou, V.; Gibson, K.; Ginsburg, C. M.; Giokaris, N.; Giromini, P.; Glagolev, V.; Glenzinski, D.; Gold, M.; Goldin, D.; Golossanov, A.; Gomez, G.; Gomez-Ceballos, G.; Goncharov, M.; González López, O.; Gorelov, I.; Goshaw, A. T.; Goulianos, K.; Gramellini, E.; Grosso-Pilcher, C.; Guimaraes da Costa, J.; Hahn, S. R.; Han, J. Y.; Happacher, F.; Hara, K.; Hare, M.; Harr, R. F.; Harrington-Taber, T.; Hatakeyama, K.; Hays, C.; Heinrich, J.; Herndon, M.; Hocker, A.; Hong, Z.; Hopkins, W.; Hou, S.; Hughes, R. E.; Husemann, U.; Hussein, M.; Huston, J.; Introzzi, G.; Iori, M.; Ivanov, A.; James, E.; Jang, D.; Jayatilaka, B.; Jeon, E. J.; Jindariani, S.; Jones, M.; Joo, K. K.; Jun, S. Y.; Junk, T. R.; Kambeitz, M.; Kamon, T.; Karchin, P. E.; Kasmi, A.; Kato, Y.; Ketchum, W.; Keung, J.; Kilminster, B.; Kim, D. H.; Kim, H. S.; Kim, J. E.; Kim, M. J.; Kim, S. H.; Kim, S. B.; Kim, Y. J.; Kim, Y. K.; Kimura, N.; Kirby, M.; Kondo, K.; Kong, D. J.; Konigsberg, J.; Kotwal, A. V.; Kreps, M.; Kroll, J.; Kruse, M.; Kuhr, T.; Kurata, M.; Laasanen, A. T.; Lammel, S.; Lancaster, M.; Lannon, K.; Latino, G.; Lee, H. S.; Lee, J. S.; Leo, S.; Leone, S.; Lewis, J. D.; Limosani, A.; Lipeles, E.; Lister, A.; Liu, Q.; Liu, T.; Lockwitz, S.; Loginov, A.; Lucchesi, D.; Lucà, A.; Lueck, J.; Lujan, P.; Lukens, P.; Lungu, G.; Lys, J.; Lysak, R.; Madrak, R.; Maestro, P.; Malik, S.; Manca, G.; Manousakis-Katsikakis, A.; Marchese, L.; Margaroli, F.; Marino, P.; Matera, K.; Mattson, M. E.; Mazzacane, A.; Mazzanti, P.; McNulty, R.; Mehta, A.; Mehtala, P.; Mesropian, C.; Miao, T.; Mietlicki, D.; Mitra, A.; Miyake, H.; Moed, S.; Moggi, N.; Moon, C. S.; Moore, R.; Morello, M. J.; Mukherjee, A.; Muller, Th.; Murat, P.; Mussini, M.; Nachtman, J.; Nagai, Y.; Naganoma, J.; Nakano, I.; Napier, A.; Nett, J.; Nigmanov, T.; Nodulman, L.; Noh, S. Y.; Norniella, O.; Oakes, L.; Oh, S. H.; Oh, Y. D.; Okusawa, T.; Orava, R.; Ortolan, L.; Pagliarone, C.; Palencia, E.; Palni, P.; Papadimitriou, V.; Parker, W.; Pauletta, G.; Paulini, M.; Paus, C.; Phillips, T. J.; Piacentino, G.; Pianori, E.; Pilot, J.; Pitts, K.; Plager, C.; Pondrom, L.; Poprocki, S.; Potamianos, K.; Pranko, A.; Prokoshin, F.; Ptohos, F.; Punzi, G.; Redondo Fernández, I.; Renton, P.; Rescigno, M.; Rimondi, F.; Ristori, L.; Robson, A.; Rodriguez, T.; Rolli, S.; Ronzani, M.; Roser, R.; Rosner, J. L.; Ruffini, F.; Ruiz, A.; Russ, J.; Rusu, V.; Sakumoto, W. K.; Sakurai, Y.; Santi, L.; Sato, K.; Saveliev, V.; Savoy-Navarro, A.; Schlabach, P.; Schmidt, E. E.; Schwarz, T.; Scodellaro, L.; Scuri, F.; Seidel, S.; Seiya, Y.; Semenov, A.; Sforza, F.; Shalhout, S. Z.; Shears, T.; Shepard, P. F.; Shimojima, M.; Shochet, M.; Shreyber-Tecker, I.; Simonenko, A.; Sliwa, K.; Smith, J. R.; Snider, F. D.; Song, H.; Sorin, V.; St. Denis, R.; Stancari, M.; Stentz, D.; Strologas, J.; Sudo, Y.; Sukhanov, A.; Suslov, I.; Takemasa, K.; Takeuchi, Y.; Tang, J.; Tecchio, M.; Teng, P. K.; Thom, J.; Thomson, E.; Thukral, V.; Toback, D.; Tokar, S.; Tollefson, K.; Tomura, T.; Tonelli, D.; Torre, S.; Torretta, D.; Totaro, P.; Trovato, M.; Ukegawa, F.; Uozumi, S.; Vázquez, F.; Velev, G.; Vellidis, C.; Vernieri, C.; Vidal, M.; Vilar, R.; Vizán, J.; Vogel, M.; Volpi, G.; Wagner, P.; Wallny, R.; Wang, S. M.; Waters, D.; Wester, W. C.; Whiteson, D.; Wicklund, A. B.; Wilbur, S.; Williams, H. H.; Wilson, J. S.; Wilson, P.; Winer, B. L.; Wittich, P.; Wolbers, S.; Wolfe, H.; Wright, T.; Wu, X.; Wu, Z.; Yamamoto, K.; Yamato, D.; Yang, T.; Yang, U. K.; Yang, Y. C.; Yao, W.-M.; Yeh, G. P.; Yi, K.; Yoh, J.; Yorita, K.; Yoshida, T.; Yu, G. B.; Yu, I.; Zanetti, A. M.; Zeng, Y.; Zhou, C.; Zucchelli, S.; CDF Collaboration

    2016-06-01

    At the Fermilab Tevatron proton-antiproton (p p ¯) collider, Drell-Yan lepton pairs are produced in the process p p ¯→e+e-+X through an intermediate γ*/Z boson. The forward-backward asymmetry in the polar-angle distribution of the e- as a function of the e+e--pair mass is used to obtain sin2θefflept, the effective leptonic determination of the electroweak-mixing parameter sin2θW. The measurement sample, recorded by the Collider Detector at Fermilab (CDF), corresponds to 9.4 fb-1 of integrated luminosity from p p ¯ collisions at a center-of-momentum energy of 1.96 TeV, and is the full CDF Run II data set. The value of sin2θefflept is found to be 0.23248 ±0.00053 . The combination with the previous CDF measurement based on μ+μ- pairs yields sin2θefflept=0.23221±0.00046 . This result, when interpreted within the specified context of the standard model assuming sin2θW=1 - MW2/MZ2 and that the W - and Z -boson masses are on-shell, yields sin2θW=0.22400 ±0.00045 , or equivalently a W -boson mass of 80.328 ±0.024 GeV /c2 .

  8. Institutional total energy case studies

    Energy Technology Data Exchange (ETDEWEB)

    Wulfinghoff, D.

    1979-07-01

    Profiles of three total energy systems in institutional settings are provided in this report. The plants are those of Franciscan Hospital, a 384-bed facility in Rock Island, Illinois; Franklin Foundation Hospital, a 100-bed hospital in Franklin, Louisiana; and the North American Air Defense Command Cheyenne Mountain Complex, a military installation near Colorado Springs, Colorado. The case studies include descriptions of plant components and configurations, operation and maintenance procedures, reliability, relationships to public utilities, staffing, economic efficiency, and factors contributing to success.

  9. Total synthesis of (-)- and (+)-tedanalactam

    Digital Repository Service at National Institute of Oceanography (India)

    Majik, M.S.; Parameswaran, P.S.; Tilve, S.G.

    : The Journal of Organic Chemistry, vol.74(16); 6378-6381 1 Total Synthesis of (-) and (+)-Tedanalactam Mahesh S. Majik, † Peruninakulath S. Parameswaran, ‡ and Santosh G. Tilve* ,† Department of Chemistry, Goa University, Taleigao Plateau, Goa 403..., displaying a wide range of biological activities. 1 Piperidones are key synthetic intermediates 2 for the synthesis of piperidine ring due to the presence of keto function which allows the introduction of other groups. Piperidones are also known...

  10. Intrathoracic Hernia after Total Gastrectomy

    Directory of Open Access Journals (Sweden)

    Yoshihiko Tashiro

    2016-05-01

    Full Text Available Intrathoracic hernias after total gastrectomy are rare. We report the case of a 78-year-old man who underwent total gastrectomy with antecolic Roux-Y reconstruction for residual gastric cancer. He had alcoholic liver cirrhosis and received radical laparoscopic proximal gastrectomy for gastric cancer 3 years ago. Early gastric cancer in the remnant stomach was found by routine upper gastrointestinal endoscopy. We initially performed endoscopic submucosal dissection, but the vertical margin was positive in a pathological result. We performed total gastrectomy with antecolic Roux-Y reconstruction by laparotomy. For adhesion of the esophageal hiatus, the left chest was connected with the abdominal cavity. A pleural defect was not repaired. Two days after the operation, the patient was suspected of having intrathoracic hernia by chest X-rays. Computed tomography showed that the transverse colon and Roux limb were incarcerated in the left thoracic cavity. He was diagnosed with intrathoracic hernia, and emergency reduction and repair were performed. Operative findings showed that the Roux limb and transverse colon were incarcerated in the thoracic cavity. After reduction, the orifice of the hernia was closed by suturing the crus of the diaphragm with the ligament of the jejunum and omentum. After the second operation, he experienced anastomotic leakage and left pyothorax. Anastomotic leakage was improved with conservative therapy and he was discharged 76 days after the second operation.

  11. NIF total neutron yield diagnostic

    International Nuclear Information System (INIS)

    Cooper, Gary W.; Ruiz, Carlos L.

    2001-01-01

    We have designed a total neutron yield diagnostic for the National Ignition Facility (NIF) which is based on the activation of In and Cu samples. The particular approach that we have chosen is one in which we calibrate the entire counting system and which we call the ''F factor'' method. In this method, In and/or Cu samples are exposed to known sources of DD and DT neutrons. The activated samples are then counted with an appropriate system: a high purity Ge detector for In and a NaI coincidence system for Cu. We can then calculate a calibration factor, which relates measured activity to total neutron yield. The advantage of this approach is that specific knowledge of such quantities as cross sections and detector efficiencies is not needed. Unless the actual scattering environment of the NIF can be mocked up in the calibration experiment, the F factor will have to be modified using the results of a numerical simulation of the NIF scattering environment. In this article, the calibration factor methodology will be discussed and experimental results for the calibration factors will be presented. Total NIF neutron yields of 10 9 --10 19 can be measured with this method assuming a 50 cm stand-off distance can be employed for the lower yields

  12. Refractory iron-deficiency anemia and gluten intolerance: Response to gluten-free diet Anemia ferropénica refractaria e intolerancia al gluten: respuesta a la dieta sin gluten

    Directory of Open Access Journals (Sweden)

    Luis Rodrigo-Sáez

    2011-07-01

    : determinar la prevalencia de marcadores serológicos, genéticos e histológicos de intolerancia al gluten y analizar la respuesta a la retirada del gluten de la dieta en estos pacientes. Métodos: se incluyeron de forma prospectiva y consecutiva una serie de pacientes con anemia refractaria. Se les aplicó un protocolo consistente en determinación marcadores serológicos (TGt-2, genéticos (HLA-DQ2/DQ8 e histológicos de enfermedad celíaca. Todos siguieron una dieta sin gluten durante una mediana de 3,6 años. Se interpretó como respuesta positiva la desaparición mantenida de la anemia durante el seguimiento. Resultados: se estudiaron 98 pacientes (84% mujeres con una edad media de 54 años. Los ac. anti-TGt2 fueron positivos en el 5% de los casos. Un total de 67 casos (68% presentaban el haplotipo HLA-DQ2 o DQ8 (+. Encontramos atrofia vellositaria (Marsh III en el 13% de los casos y patrón inflamatorio (Marsh I o II en el 13%. Los 72 casos restantes (74% no presentaban alteraciones histológicas duodenales. Se compararon la edad, el tiempo de evolución de la anemia, número de transfusiones, número de dosis de hierro parenteral y tiempo en dieta sin gluten, en función de la presencia o no de atrofia vellositaria y de la positividad para el HLA-DQ2/8, sin encontrar diferencias significativas en ninguna de las variables analizadas. La respuesta fue positiva en el 92% de los casos. Conclusiones: la enfermedad celiaca con atrofia vellositaria es causa poco frecuente de anemia refractaria. Las formas de intolerancia al gluten sin lesión histológica asociada, representan cerca del 75% de los casos y desempeñan, por lo tanto, un papel importante en su aparición.

  13. Total eclipses of the sun

    CERN Document Server

    Zirker, Jack B

    2014-01-01

    Eclipses have captured attention and sparked curiosity about the cosmos since the first appearance of humankind. Having been blamed for everything from natural disasters to the fall of kings, they are now invaluable tools for understanding many celestial as well as terrestrial phenomena. This clear, easy-to-understand guide explains what causes total eclipses and how they can be used in experiments to examine everything from the dust between the planets to general relativity. A new chapter has been added on the eclipse of July 11, 1991 (the great Hawaiian eclipse). Originally published in 19

  14. Reverse hybrid total hip arthroplasty

    DEFF Research Database (Denmark)

    Wangen, Helge; Havelin, Leif I.; Fenstad, Anne M

    2017-01-01

    Background and purpose - The use of a cemented cup together with an uncemented stem in total hip arthroplasty (THA) has become popular in Norway and Sweden during the last decade. The results of this prosthetic concept, reverse hybrid THA, have been sparsely described. The Nordic Arthroplasty....... Patients and methods - From the NARA, we extracted data on reverse hybrid THAs from January 1, 2000 until December 31, 2013. 38,415 such hips were studied and compared with cemented THAs. The Kaplan-Meier method and Cox regression analyses were used to estimate the prosthesis survival and the relative risk...

  15. Total knee arthroplasty in ochronosis

    Directory of Open Access Journals (Sweden)

    Vaibhav G. Patel, MBBS

    2015-09-01

    Full Text Available Alkaptonuria is disorder of tyrosine metabolism due to deficiency of homogentisic oxidase characterized by excretion of homogentisic acid in urine, deposition of oxidized homogensitate pigments in connective tissues and articular cartilages (ochronosis. The result is dark pigmentation and weakening of the tissues resulting in chronic inflammation and osteoarthritis. Management of alkaptonuric ochronic osteoarthritis is usually symptomatic and replacements have comparable outcomes to osteoarthritis in patients without ochronosis. I report a case of a patient with ochronosis of knee treated with total knee replacement and report operative pearls for surgery in this rare disorder.

  16. Total filmless digital radiology service

    International Nuclear Information System (INIS)

    Mun, S.K.; Goeringer, F.; Benson, H.; Horii, S.C.

    1989-01-01

    The completion of a comprehensive picture archiving and communication system (PACS) at Georgetown University Hospital has allowed us to identify a number of technical, administrative, personnel, and operational issues that will affect a total digital radiology service. With a hospital-wide digital imaging network system, computer simulation of communications and storage options, and economic modeling, we have developed a feasibility study and implementation strategy for the smooth transition to a nearly filmless radiology service over the next several years. This paper describes the technical and operational requirements for various database operations, workstations (used in diagnosis, review, and education), and communications. Site and installation planning, personnel training, and transition operations are discussed

  17. Indicaciones, técnicas y resultados de reemplazo total de cadera en estados unidos

    Directory of Open Access Journals (Sweden)

    Robert W. Bucholz

    2014-09-01

    Full Text Available Hace 50 años, Sir John Charnley introdujo la era del reemplazo total de cadera. Sus innovaciones en la fijación de la prótesis con polimetilmetacrilato, el par de fricción de metal/ polietileno, la instrumentación estandarizada y los quirófanos con aire purificado, revolucionaron los intentos previos a reemplazar caderas con artrosis. En Estados Unidos, los principios y la prótesis de Charnley fueron adoptados, investigados y modificados tal como lo ha sido en otros países. Sin embargo, su técnica y conceptos básicos siguen estando vigentes y el reemplazo total de cadera es ampliamente considerado uno de los procedimientos quirúrgicos más exitosos en la cirugía ortopédica. Más de 400.000 reemplazos de cadera son realizados anualmente en los Estados Unidos.

  18. Qualidade total: Um novo paradigma?

    Directory of Open Access Journals (Sweden)

    Suzana da Rosa Tolfo

    1999-01-01

    Full Text Available Nos últimos anos, o movimento para a implantação da Gestão da Qualidade Total vem crescendo ao redor do mundo. Em razão disso, há uma diversidade de ações realizadas com o nome de "Qualidade Total'. Uma revisão da teoria é complexa, porque existem muitos autores que tratam da questão. Eles escolhem diferentes perspectivas de análises (teóricas e empíricas e há dificuldades em se identificar um corpo conceitual. Há uma ampla difusão de modelos, ferramentas, técnicas, mercado e consultores. Essa popularidade, muitas vezes, faz com que determinadas organizações adotem essa forma de gestão do trabalho sem o conhecimento necessário das implicações que um modelo dessa ordem representa; especialmente no caso brasileiro, suscetível a proposições importadas. O presente artigo propõe um exame daquilo que os fundadores têm articulado sobre TQM, as principais críticas nesta direção e a avaliação de como vem sendo aplicadono nosso país.

  19. Testing EDM of Total Stations

    Directory of Open Access Journals (Sweden)

    Cirbus Ján

    2001-03-01

    Full Text Available The paper is devoted to testing electrooptical distance measuring devices (EDM built in total stations, than can be used for various tasks in the contemporary geodetic works. A rich market offer and availability of these universal measuring systems with satisfying distance range, excellent accuracy and other parameters, make total stations as dominant terrestrial geodetic instruments.For succesfully applying these instruments, above all for relliable distance measurements, the stability of the modulation frequency is the most important pre-condition. In the article, therefore, there are given some methods to verify the modulation frequency stability. In addition, some ways for determining the EDM distance constant and periodical corrections of the phase measuring unit are introduced for 4 types of EDM : LEICA 1700L, TOPCON GTS6A, TOPCON GTS2, C.ZEISS ELTA50. It were also investigated their possibilities for precise distance survey. Values of the determined constants and periodical corrections are presented in Tab. 2.Based on the investigation results of the 4 EDM types and using the values m obtained for different distances S, equations of the a posteriori standard deviations in form : m = (a+b.S were derived too.

  20. Total Value of Phosphorus Recovery.

    Science.gov (United States)

    Mayer, Brooke K; Baker, Lawrence A; Boyer, Treavor H; Drechsel, Pay; Gifford, Mac; Hanjra, Munir A; Parameswaran, Prathap; Stoltzfus, Jared; Westerhoff, Paul; Rittmann, Bruce E

    2016-07-05

    Phosphorus (P) is a critical, geographically concentrated, nonrenewable resource necessary to support global food production. In excess (e.g., due to runoff or wastewater discharges), P is also a primary cause of eutrophication. To reconcile the simultaneous shortage and overabundance of P, lost P flows must be recovered and reused, alongside improvements in P-use efficiency. While this motivation is increasingly being recognized, little P recovery is practiced today, as recovered P generally cannot compete with the relatively low cost of mined P. Therefore, P is often captured to prevent its release into the environment without beneficial recovery and reuse. However, additional incentives for P recovery emerge when accounting for the total value of P recovery. This article provides a comprehensive overview of the range of benefits of recovering P from waste streams, i.e., the total value of recovering P. This approach accounts for P products, as well as other assets that are associated with P and can be recovered in parallel, such as energy, nitrogen, metals and minerals, and water. Additionally, P recovery provides valuable services to society and the environment by protecting and improving environmental quality, enhancing efficiency of waste treatment facilities, and improving food security and social equity. The needs to make P recovery a reality are also discussed, including business models, bottlenecks, and policy and education strategies.

  1. How to arrest a core meltdown accident (doing nothing); Como detener un accidente con fusion de nucleo (sin hacer nada)

    Energy Technology Data Exchange (ETDEWEB)

    Baron, Jorge H [Autoridad Regulatoria Nuclear, Buenos Aires (Argentina)

    2000-07-01

    In the eventual situation of a severe accident in a nuclear reactor, the molten core is able to relocate inside the pressure vessel. This may lead to the vessel failure, due to the thermal attack of the molten core (at approximation of 3000K) on the vessel steel wall. The vessel failure implies the failure of a very important barrier that contains the radioactive materials generated during the reactor operation, with a significant risk of producing high radiation doses both on operators and on the public. It is expected, for the new generation of nuclear reactors, that these will be required to withstand (by design) a core melt down accident, without the need for an immediate evacuation of the surrounding population. In this line, the use of a totally passive system is postulated, which fulfills the objective of containing the molten core inside the pressure vessel, at low temperature (approximation 1200K) precluding its failure. The conceptual design of a passive in-vessel core catcher is presented in this paper, built up of zinc, and designed for the CAREM-25 nuclear power plant. (author)

  2. Uranium-lead dating of hydrothermal zircon and monazite from the Sin Quyen Fe-Cu-REE-Au-(U) deposit, northwestern Vietnam

    Science.gov (United States)

    Li, Xiao-Chun; Zhou, Mei-Fu; Chen, Wei Terry; Zhao, Xin-Fu; Tran, MyDung

    2018-03-01

    The Sin Quyen deposit in northwestern Vietnam contains economic concentrations of Cu, Au and LREE, and sub-economic concentration of U. In this deposit, massive and banded replacement ores are hosted in Neoproterozoic metapelite. The paragenetic sequence includes sodic alteration (stage I), calcic-potassic alteration and associated Fe-REE-(U) mineralization (stage II), Cu-Au mineralization (stage III), and sulfide-(quartz-carbonate) veins (stage IV). The Sin Quyen deposit experienced an extensive post-ore metamorphic overprint, which makes it difficult to precisely determine the mineralization age. In this study, zircon and monazite U-Pb geochronometers and the Rb-Sr isochron method are used to constrain the timing of mineralization. Zircon grains in the ore are closely intergrown or texturally associated with hydrothermal minerals of stage II (e.g., garnet, allanite, and hedenbergite). They may contain primary fluid inclusions and display irregular zoning in cathodoluminescence (CL) images. Zircon grains are rich in U (688 to 2902 ppm) and poor in Th (0.2 to 2.9 ppm). Their δ18OV-SMOW values range from 11.9 to 14.0‰, higher than those of typical magmatic zircon. These textural and compositional features imply that zircon precipitated from 18O- and U-rich hydrothermal fluids, coeval with the minerals of stage II. Monazite occurs in close association with stage II magnetite and allanite and has low contents of Th (<2700 ppm), indicative of a hydrothermal origin. Hydrothermal zircon and monazite have indistinguishable U-Pb ages of 841 ± 12 and 836 ± 18 Ma, respectively, representing the timing of Fe-REE mineralization. There is no direct isotopic constraint on the timing of the Cu-Au mineralization, but geological observations suggest that the Cu-Au and Fe-REE ores most likely formed within a single evolved hydrothermal process. In the plot of 87Rb/86Sr vs. 87Sr/86Sr, the composition of bulk-ore and biotite separates from ore lie along a reference line for 30 Ma

  3. Efecto del kinesiotaping con y sin tensión aplicado en cuadríceps sobre la capacidad de salto en deportistas

    Directory of Open Access Journals (Sweden)

    Mayerly Carolina Anaya

    2015-06-01

    Full Text Available Antecedentes: Estudios previos han encontrado que la técnica del Kinesiotaping (KT reduce la intensidad y duración del dolor y la inflamación, incrementa la fuerza muscular y estabiliza las articulaciones. Sin embargo, poco se conoce sobre su efecto para mejorar las capacidades físicas a través de la estimulación muscular en deportistas. Objetivo: Evaluar el efecto del KT aplicado en el cuadríceps sobre la capacidad de salto vertical en deportistas sanos, ajustado por el porcentaje de coordinación y elasticidad, edad e Índice de Masa Corporal. Metodología: Estudio experimental realizado en 24 voleibolistas, aleatorizados en dos grupos: (1 12 sujetos (21.3 ± 3.4 años, 75.6 ± 13.9Kg, con aplicación del KT en cuádriceps femoral con tensión; (2 12 sujetos (20.5± 2.9 años, 71.8 ± 6.8 Kg con aplicación del KT en cuádriceps femoral sin tensión. Resultados: Los datos no mostraron diferencias estadísticamente significativas en la aplicación del KT con y sin tensión; se encontró asociación estadísticamente significativa entre el porcentaje de coordinación y la altura del salto alcanzado en la prueba de Abalakov (p=0,006, cuando el KT tenía tensión y ajustado por edad e IMC. Discusión y conclusiones: La técnica KT no mejora del desempeño del salto en deportistas sanos. No se debería aplicar KT en el cuadríceps femoral con el único objetivo de mejorar el salto en jugadores de voleibol saludables masculinos.

  4. Efecto del cambio del paisaje en la estructura de la comunidad de abejas sin aguijón (Hymenoptera: Apidae en Meta, Colombia

    Directory of Open Access Journals (Sweden)

    Guiomar Nates-Parra

    2008-09-01

    Full Text Available Las abejas sin aguijón son unos de los polinizadores naturales más diversos de la fauna Apoidea en los trópicos. Nidifican en diversos sustratos y distintos ambientes, existiendo algunas especies típicas de lugares naturales o artificiales. La alteración del medio donde nidifican tiene un importante impacto sobre la composición natural de su estructura, hecho que se ve reflejado también en la densidad de nidos. Analizamos la composición de la estructura de la comunidad de abejas sin aguijón en tres paisajes del piedemonte llanero colombiano, una región importante por representar la transición entre ambientes andinos y de sabana (seriamente amenazada por la ganadería intensiva. Realizamos muestreos sistemáticos en bosque secundario, agro-ecosistema y zona urbana; registramos la presencia de 204 nidos de 11 géneros representados por 24 especies. La riqueza de abejas sin aguijón fue similar, aun cuando hubo diferencias significativas en la estructura de la comunidad en los tres paisajes. La densidad de nidos por paisaje fue heterogénea y nunca mayor de 16 nidos/Ha. Observamos dos patrones de nidificación y registramos diferente número de especies en la misma zona utilizando otro criterio de muestreo.Effect of landscape change on the structure of the sting-less bee community (Hymenoptera: Apidae in Meta, Colombia. Stingless bees represent one of the most diversified components of the natural Apoidea fauna of pollinators in the tropics. They use diverse kinds of substrates and inhabit varied habitats. Some species are typical for some natural either artificial place. The landscape alteration were this group of bees nests, has and important impact on the natural composition of its community structure, fact which is reflected in the nest density. We analyzed the structure composition of the stingless bees’ community in three environments in the Colombian llanos piedmont, an important region that represents the transition between

  5. El concepto de esquema corporal en niñas y niños con y sin necesidades educativas especiales, de preescolar, segundo y cuarto grado

    Directory of Open Access Journals (Sweden)

    Zulay Pereira-Pérez

    2006-06-01

    Full Text Available La investigación realizada acerca del concepto de esquema corporal de niñas y niños con y sin necesidades educativas especiales (nee de preescolar, segundo y cuarto grados, proporciona información relevante sobre la construcción de este concepto. La mayor parte de las y los estudiantes con necesidades educativas especiales, de los tres niveles educativos, expresan conceptos de cuerpo relacionados con las características y las cualidades corporales, aunque algunos también refieren a habilidades corporales. Es importante resaltar que estos conceptos no presentan diferencias sustanciales con los expresados por las y los estudiantes sin necesidades educativas. El número de partes del cuerpo mencionadas aumenta a medida que lo hace el nivel educativo y se ve reflejado en las representaciones gráficas de sus cuerpos. No obstante, la mayoría de las y los estudiantes con necesidades educativas especiales presentaron mayor dificultad en la ubicación de partes del cuerpo con su respectiva lateralidad. Conforme aumenta a nivel educativo, se identifica que las y los estudiantes con necesidades educativas especiales asumen las labores domésticas y expresan tener mayor dificultad para las actividades escolares. Asimismo, indican que sienten malestar cuando las personas importantes de su entorno les dicen cosas relacionadas con su cuerpo. No obstante, la mayoría de las y los estudiantes con y sin necesidades educativas especiales expresan percepciones positivas relacionadas con su cuerpo y tienen un sentimiento de respeto por sí mismas(os. Por lo anterior, se recomienda que en los procesos educativos se tomen en consideración los conocimientos previos de las y los estudiantes y se enfatice en la enseñanza de aspectos no solo referidos a conocimientos del cuerpo, sino relacionados con la imagen corporal. Es valiosa la aplicación de actividades didácticas que permitan la vivencia y construcción de los conceptos estudiados, para prevenir los

  6. Total employment effect of biofuels

    International Nuclear Information System (INIS)

    Stridsberg, S.

    1998-08-01

    The study examined the total employment effect of both direct production of biofuel and energy conversion to heat and electricity, as well as the indirect employment effect arising from investments and other activities in conjunction with the production organization. A secondary effect depending on the increased capital flow is also included in the final result. The scenarios are based on two periods, 1993-2005 and 2005-2020. In the present study, the different fuels and the different applications have been analyzed individually with regard to direct and indirect employment within each separate sector. The greatest employment effect in the production chain is shown for logging residues with 290 full-time jobs/TWh, whereas other biofuels range between 80 and 280 full-time jobs/TWh. In the processing chain, the corresponding range is 200-300 full-time jobs per each additional TWh. Additionally and finally, there are secondary effects that give a total of 650 full-time jobs/TWh. Together with the predicted increase, this suggests that unprocessed fuel will provide an additional 16 000 annual full-time jobs, and that fuel processing will contribute with a further 5 000 full-time jobs. The energy production from the fuels will provide an additional 13 000 full-time jobs. The total figure of 34 000 annual full-time jobs must then be reduced by about 4000 on account of lost jobs, mainly in the oil sector and to some extent in imports of biofuel. In addition, the anticipated increase in capital turnover that occurs within the biofuel sector, will increase full-time jobs up to year 2020. Finally, a discussion is given of the accomplishment of the programmes anticipated by the scenario, where it is noted that processing of biofuel to wafers, pellets or powder places major demands on access to raw material of good quality and that agrarian fuels must be given priority if they are to enter the system sufficiently fast. Straw is already a resource but is still not accepted by

  7. Rutas de señalización celular involucradas en la plasticidad post-sináptica inducida por la activación de los canales de glutamato tipo NMDA en el hipocampo

    Directory of Open Access Journals (Sweden)

    Sebastián Patrón Saade

    2005-01-01

    Full Text Available La apertura de los canales de glutamato tipo NMDA, gracias a la acción concomitante de las neuronas pre-sináptica y post-sináptica a nivel de las espinas dendríticas, induce a modificaciones de la fuerza y eficacia sinápticas en éstas, fenómeno mejor conocido como plasticidad sináptica. Las dos formas conocidas de plasticidad sinápticas son la potenciación a largo plazo (LTP y la depresión a largo plazo (LTD. Subyacen a ambos tipos de plasticidad modificaciones covalentes sobre las distintas proteínas que componen la densidad post-sináptica y, en caso de que la LTP se prolongue, una regulación activa de la transcripción y traducción de material genético. Así, la regulación activa de la fuerza y eficacia sináptica se debe al control activo sobre la tasa de inserción y remoción de los receptores de glutamato tipo AMPA, receptores encargados de la excitación rápida en el cerebro. Lo significativo de dicho evento en el hipocampo se debe a que éste está relacionado de manera estrecha con la memoria declarativa de los individuos, su memoria de reconocimiento y la memoria espacial, esta última mediada por la activación precisa y coordinada de las células de lugar que se encuentran en él.

  8. Conversion total hip arthroplasty: Primary or revision total hip arthroplasty

    Science.gov (United States)

    Schwarzkopf, Ran; Baghoolizadeh, Mahta

    2015-01-01

    Total hip arthroplasty (THA) is an increasingly common procedure among elderly individuals. Although conversion THA is currently bundled in a diagnosis related group (DRG) with primary THA, there is a lack of literature supporting this classification and it has yet to be identified whether conversion THA better resembles primary or revision THA. This editorial analyzed the intraoperative and postoperative factors and functional outcomes following conversion THA, primary THA, and revision THA to understand whether the characteristics of conversion THA resemble one procedure or the other, or are possibly somewhere in between. The analysis revealed that conversion THA requires more resources both intraoperatively and postoperatively than primary THA. Furthermore, patients undergoing conversion THA present with poorer functional outcomes in the long run. Patients undergoing conversion THA better resemble revision THA patients than primary THA patients. As such, patients undergoing conversion THA should not be likened to patients undergoing primary THA when determining risk stratification and reimbursement rates. Conversion THA procedures should be planned accordingly with proper anticipation of the greater needs both in the operating room, and for in-patient and follow-up care. We suggest that conversion THA be reclassified in the same DRG with revision THA as opposed to primary THA as a step towards better allocation of healthcare resources for conversion hip arthroplasties. PMID:26601055

  9. El Estado sin territorio: La desaparición del territorio debido al cambio climático

    Directory of Open Access Journals (Sweden)

    Mariano J. Aznar Gómez

    2013-12-01

    Full Text Available Diversos y fundados análisis científicos demuestran que una de las derivadas del denominado “cambio climático” es el calentamiento global del planeta y, con él, la posible elevación significativa de los niveles de mares y océanos en el planeta. Ello podría suponer, en determinados casos, la desaparición bajo las aguas de amplias porciones del territorio de diversos Estados, muy particularmente de ciertos Estados archipelágicos del Pacífico que podrían ver, incluso, la total desaparición de sus espacios terrestres. Con ello desaparecería uno de los elementos constitutivos del Estado, cuestionándose entonces sus efectos en la soberanía e, incluso, en la propia existencia de dicho Estado. Quedaría igualmente afectado otro elemento de la estatalidad: la población, que podría verse desplazada conformando una nueva tipología de “desplazados climáticos”. El Derecho internacional actual ofrece diversas soluciones a dichos problemas, si bien parte de la adopción de esas soluciones implicarían la asunción de opciones políticas de cierta envergadura con efectos jurídicos reseñables. Este trabajo analiza parte de estas cuestiones, proponiendo algunas de las mismas como posibles soluciones a la posible alteración territorial o la desaparición de ciertos Estados debida al cambio climático.

  10. Instability after total hip arthroplasty

    Science.gov (United States)

    Werner, Brian C; Brown, Thomas E

    2012-01-01

    Instability following total hip arthroplasty (THA) is an unfortunately frequent and serious problem that requires thorough evaluation and preoperative planning before surgical intervention. Prevention through optimal index surgery is of great importance, as the management of an unstable THA is challenging even for an experienced joints surgeon. However, even after well-planned surgery, a significant incidence of recurrent instability still exists. Non-operative management is often successful if the components are well-fixed and correctly positioned in the absence of neurocognitive disorders. If conservative management fails, surgical options include revision of malpositioned components; exchange of modular components such as the femoral head and acetabular liner; bipolar arthroplasty; tripolar arthroplasty; use of a larger femoral head; use of a constrained liner; soft tissue reinforcement and advancement of the greater trochanter. PMID:22919568

  11. A total safety management model

    International Nuclear Information System (INIS)

    Obadia, I.J.; Vidal, M.C.R.; Melo, P.F.F.F.

    2002-01-01

    In nuclear organizations, quality and safety are inextricably linked. Therefore, the search for excellence means reaching excellence in nuclear safety. The International Atomic Energy Agency, IAEA, developed, after the Chernobyl accident, the organizational approach for improving nuclear safety based on the safety culture, which requires a framework necessary to provide modifications in personnel attitudes and behaviors in situations related to safety. This work presents a Total Safety Management Model, based on the Model of Excellence of the Brazilian Quality Award and on the safety culture approach, which represents an alternative to this framework. The Model is currently under validation at the Nuclear Engineering Institute, in Rio de Janeiro, Brazil, and the results of its initial safety culture self assessment are also presented and discussed. (author)

  12. Demand: a total nuclear disarmament

    International Nuclear Information System (INIS)

    Hessel, Stephane; Jacquard, Albert

    2012-01-01

    This bibliographical note presents a book, in which the authors make a plea for a total nuclear disarmament. They think that humanity cannot be found in competition, but in emulation, and examine how we can get rid of the nuclear bomb. They discuss the background of nuclear energy, state that nuclear weapons have always been useless and extremely dangerous, consider arms race as crazy and as a crime against humanity, recall that nuclear weapons already made numerous victims (Hiroshima, Nagasaki, nuclear tests), that they are a sword of Damocles over 7 billions human beings, that nuclear winter would be an apocalypse, that the Non Proliferation Treaty is a decoy. They discuss the political role of nuclear weapons, and outline that the only solution is their abolition. They discuss what has already been done and what is still to be done, and formulate a strategy for the future

  13. Total synthesis of mycalamide A.

    Science.gov (United States)

    Sohn, Jeong-Hun; Waizumi, Nobuaki; Zhong, H Marlon; Rawal, Viresh H

    2005-05-25

    This communication describes a concise and efficient total synthesis of mycalamide A by the convergent coupling of pederic acid unit with the mycalamine unit. The left-half, (+)-7-benzoylpederic acid, was synthesized from (2R,3R)-3-methylpent-4-en-2-ol in seven steps and 34.6% overall yield through a route that features a one-step Pd(II)-catalyzed tandem Wacker/Heck cyclization reaction to prepare the tetrahydropyran ring system. The right-half, the mycalamine unit, was synthesized in 21 steps and 10.5% overall yield from diethyl d-tartrate. Effective, stereoselective methods were developed for the assembly of the two parts to yield either mycalamide A or C(10)-epi-mycalamide A.

  14. Total quality management implementation guidelines

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-01

    These Guidelines were designed by the Energy Quality Council to help managers and supervisors in the Department of Energy Complex bring Total Quality Management to their organizations. Because the Department is composed of a rich mixture of diverse organizations, each with its own distinctive culture and quality history, these Guidelines are intended to be adapted by users to meet the particular needs of their organizations. For example, for organizations that are well along on their quality journeys and may already have achieved quality results, these Guidelines will provide a consistent methodology and terminology reference to foster their alignment with the overall Energy quality initiative. For organizations that are just beginning their quality journeys, these Guidelines will serve as a startup manual on quality principles applied in the Energy context.

  15. Total quality management program planning

    Energy Technology Data Exchange (ETDEWEB)

    Thornton, P.T.; Spence, K.

    1994-05-01

    As government funding grows scarce, competition between the national laboratories is increasing dramatically. In this era of tougher competition, there is no for resistance to change. There must instead be a uniform commitment to improving the overall quality of our products (research and technology) and an increased focus on our customers` needs. There has been an ongoing effort to bring the principles of total quality management (TQM) to all Energy Systems employees to help them better prepare for future changes while responding to the pressures on federal budgets. The need exists for instituting a vigorous program of education and training to an understanding of the techniques needed to improve and initiate a change in organizational culture. The TQM facilitator is responsible for educating the work force on the benefits of self-managed work teams, designing a program of instruction for implementation, and thus getting TQM off the ground at the worker and first-line supervisory levels so that the benefits can flow back up. This program plan presents a conceptual model for TQM in the form of a hot air balloon. In this model, there are numerous factors which can individually and collectively impede the progress of TQM within the division and the Laboratory. When these factors are addressed and corrected, the benefits of TQM become more visible. As this occurs, it is hoped that workers and management alike will grasp the ``total quality`` concept as an acceptable agent for change and continual improvement. TQM can then rise to the occasion and take its rightful place as an integral and valid step in the Laboratory`s formula for survival.

  16. Instability following total knee arthroplasty.

    Science.gov (United States)

    Rodriguez-Merchan, E Carlos

    2011-10-01

    Background Knee prosthesis instability (KPI) is a frequent cause of failure of total knee arthroplasty. Moreover, the degree of constraint required to achieve immediate and long-term stability in total knee arthroplasty (TKA) is frequently debated. Questions This review aims to define the problem, analyze risk factors, and review strategies for prevention and treatment of KPI. Methods A PubMed (MEDLINE) search of the years 2000 to 2010 was performed using two key words: TKA and instability. One hundred and sixty-five initial articles were identified. The most important (17) articles as judged by the author were selected for this review. The main criteria for selection were that the articles addressed and provided solutions to the diagnosis and treatment of KPI. Results Patient-related risk factors predisposing to post-operative instability include deformity requiring a large surgical correction and aggressive ligament release, general or regional neuromuscular pathology, and hip or foot deformities. KPI can be prevented in most cases with appropriate selection of implants and good surgical technique. When ligament instability is anticipated post-operatively, the need for implants with a greater degree of constraint should be anticipated. In patients without significant varus or valgus malalignment and without significant flexion contracture, the posterior cruciate ligament (PCL) can be retained. However, the PCL should be sacrificed when deformity exists particularly in patients with rheumatoid arthritis, previous patellectomy, previous high tibial osteotomy or distal femoral osteotomy, and posttraumatic osteoarthritis with disruption of the PCL. In most cases, KPI requires revision surgery. Successful outcomes can only be obtained if the cause of KPI is identified and addressed. Conclusions Instability following TKA is a common cause of the need for revision. Typically, knees with deformity, rheumatoid arthritis, previous patellectomy or high tibial osteotomy, and

  17. EL EFECTO DE LOS IMPUESTOS A LAS TRANSACCIONES FINANCIERAS EN LA ESTABILIDAD DE LOS MERCADOS DE CAPITAL. Un debate sin resolver

    Directory of Open Access Journals (Sweden)

    Miguel A. Alonso Neira

    2013-01-01

    Full Text Available El presente artículo analiza el debate en torno de la efectividad y las repercusiones de los impuestos a las transacciones financieras (ITF. A pesar de su uso habitual en varios países del G-20, quedan sin explicar muchos aspectos relacionados con su efecto en la estabilidad de los mercados financieros. Así, aunque la bibliografía aca-démica suele coincidir en los efectos adversos de los ITF en el volumen de operacio-nes y el valor de los activos, no ocurre lo mismo en relación con sus repercusiones en la volatilidad de los precios a corto y a largo plazos, el proceso de descubrimien-to de precios y la eficiencia informativa de los mercados.

  18. Sin-wai, Chan. The Future of Translation Technology: Towards a World without Babel. London and New York: Routledge, 2017. 302 p.

    Directory of Open Access Journals (Sweden)

    Thomas Kelahan

    2018-01-01

    Full Text Available Chan Sin-wai is a professor and chairman of the Department of Translation at the Chinese University of Hong Kong, Shenzhen. Additionally, he is the director of the Center for Translation Technology as well as the university’s MA Program in Computer-aided translation.  In 2016, he published A New Comprehensive Chinese-English Dictionary, Routledge Encyclopedia of Translation Technology and Routledge Encyclopedia of the Chinese Language. His newest book, The Future of Translation Technology: Towards a World without Babel, is described as “an essential read for scholars and researchers of translation studies and computational linguistics, and a guide to system users and professionals.”

  19. OBSERVACIÓN METEOROLÓGICA SIN APARATOS. PROPUESTA DIDÁCTICA DE GEOGRAFÍA PARA EL ALUMNADO DEL PROGRAMA DE DIVERSIFICACIÓN CURRICULAR (PDC

    Directory of Open Access Journals (Sweden)

    Luis Alfonso Cruz Naïmi

    2006-12-01

    Full Text Available La observación meteorológica sin aparatos puede ser una buena forma de enseñar geografía (en particular la climatología, a la vez que es una actividad donde se potencian una serie de aspectos educativos especialmente interesantes desde el punto de vista de la atención a la diversidad, y en concreto, para los alumnos de los Programas de Diversificación Cunicular. El componente procedimental de esta actividad y la necesaria implicación de los alumnos para su realización hacen que esta propuesta sea válida para ser llevada a cabo con este tipo de alumnos.

  20. Identificación de los compuestos volátiles de frutos de papaya sin ovipositar y ovipositados por toxotrypana curvicauda (diptera: tephritidae).

    OpenAIRE

    Ruiz Gómez, Olga Lidia

    2016-01-01

    En los tefrítidos la búsqueda, localización y aceptación del hospedero, depende generalmente de estímulos químicos que pueden ser identificados por las hembras a la distancia. La emisión de compuestos volátiles del fruto, puede cambiar con la oviposición y modificar la atracción de las hembras. En el presente estudio se evaluó la atracción de hembras grávidas de Toxotrypana curvicauda hacia frutos de papaya sin ovipositar y ovipositados y se identificaron los compuestos volátiles de los fruto...

  1. Rapid evaporation at the superheat limit of methanol, ethanol, butanol and n-heptane on platinum films supported by low-stress SiN membranes.

    Science.gov (United States)

    Ching, Eric J; Avedisian, C Thomas; Cavicchi, Richard C; Chung, Do Hyun; Rah, Jeff; Carrier, Michael J

    2016-10-01

    The bubble nucleation temperatures of several organic liquids (methanol, ethanol, butanol, n-heptane) on stress-minimized platinum (Pt) films supported by SiN membranes is examined by pulse-heating the membranes for times ranging from 1 µs to 10 µs. The results show that the nucleation temperatures increase as the heating rates of the Pt films increase. Measured nucleation temperatures approach predicted superheat limits for the smallest pulse times which correspond to heating rates over 10 8 K/s, while nucleation temperatures are significantly lower for the longest pulse times. The microheater membranes were found to be robust for millions of pulse cycles, which suggests their potential in applications for moving fluids on the microscale and for more fundamental studies of phase transitions of metastable liquids.

  2. Efectos de la putrescina en diferentes ciclos de selección masal divergente del maíz Harinoso Mosquera I Sin. 2 afectados por las heladas

    Directory of Open Access Journals (Sweden)

    Jesús Antonio Norato Rodríguez

    1990-01-01

    Full Text Available During 1989, at the Tibaitata Research Center, an experiment plot was carried out. On cycles 6, 9, 12 and 15 of prolific and non prolific corn sub-populations which treated with 0, 1000, 2000 and 4000 Mm of putrescine. Six hours before aplication, the corn plants suffered chilling effects (-1.50 C/4 hr. As consecuence of chilling, the growth in height was suspended, the ear shoots and yield grain decreased. However putrescine application reverted the damage caused hy chilling and significative differences were observed in height and yield grain. Cicle 6 in prolific sub population was noticeable, in which 1000, 2000, and 4000 Mm of putrescine yielded 6.75, 5.24 and 5.63 Ton/ha. The Harinoso Mosquera I. Sin. 2 or cycle cero, showed a higber sensibility to chilling and the answer to putrescine application was almost negligeable.

  3. First Measurement of the Left-Right Charge Asymmetry in Hadronic Z Boson Decays and a New Determination of sin2θeffW

    International Nuclear Information System (INIS)

    Steiner, R.; Benvenuti, A.; Coller, J.; Hedges, S.; Johnson, A.; Shank, J.; Whitaker, J.; Allen, N.; Cotton, R.; Dervan, P.; Hasan, A.; McKemey, A.; Watts, S.; Caldwell, D.; Lu, A.; Yellin, S.; Cavalli-Sforza, M.; Coyne, D.; Liu, X.; Reinertsen, P.; Schalk, T.; Schumm, B.; Williams, D.; DOliveira, A.; Johnson, R.; Meadows, B.; Nussbaum, M.; Dima, M.; Harton, J.; Smy, M.; Wilson, R.; Baranko, G.; Fahey, S.; Fan, C.; Krishna, N.; Lauber, J.; Nauenberg, U.; Wagner, D.; Bazarko, A.; Bolton, T.; Rowson, P.; Shaevitz, M.; Camanzi, B.; Mazzucato, E.; Piemontese, L.; Calcaterra, A.; De Sangro, R.; Peruzzi, I.; Piccolo, M.; Abt, I.; Eisenstein, B.; Gladding, G.; Karliner, I.; Shapiro, G.; Steiner, H.; Bardon, O.; Burrows, P.; Busza, W.; Cowan, R.; Dong, D.; Fero, M.; Gonzalez, S.; Kendall, H.; Lath, A.; Lia, V.; Osborne, L.; Quigley, J.; Taylor, F.; Torrence, E.; Verdier, R.

    1997-01-01

    We present the first measurement of the left-right charge asymmetry A obs Q in hadronic Z boson decays. This was performed at E c.m. =91.27 GeV with the SLD at the SLAC Linear Collider with a polarized electron beam. Using 89838 events we obtain A obs Q =0.225±0.056±0.019, which leads to a measurement of the electron left-right asymmetry parameter, A e =0.162±0.041±0.014, and sin 2 θ eff W =0.2297±0.0052±0.0018. Also, the A obs Q measurement combined with the left-right cross section asymmetry determines A e independent of the value of the electron-beam polarization. copyright 1996 The American Physical Society

  4. Pincharse sin infectarse: estrategias para prevenir la infección por el VIH y el VHC entre usuarios de drogas inyectables

    Science.gov (United States)

    MATEU-GELABERT, P.; FRIEDMAN, S.; SANDOVAL, M.

    2011-01-01

    Resumen Objetivo Desde principios de los noventa, en la ciudad de Nueva York se han implementado con éxito programas para reducir la incidencia del virus de la inmunodeficiencia humana (VIH) y, en menor medida, del virus de la hepatitis C (VHC). A pesar de ello, aproximadamente el 70% de los usuario de drogas inyectables (UDI) están infectados por el VHC. Queremos investigar cómo el 30% restante se las ha arreglado para no infectarse. El Staying safe (nombre original del estudio) explora los comportamientos y mecanismos que ayudan a evitar la infección por el VHC y el VIH a largo plazo. Material y métodos Hemos utilizado el concepto de «desviación positiva» aplicado en otros campos de salud pública. Estudiamos las estrategias, prácticas y tácticas de prevención de aquellos UDI que, viviendo en contextos de alta prevalencia, se mantienen sin infectar por VIH y el VHC, a pesar de haberse inyectado heroína durante años. Los resultados preliminares presentados en este artículo incluyen el análisis de las entrevistas realizadas a 25 UDI (17 doble negativos, 3 doble positivos y 5 con infección por el VHC y sin infección por el VIH). Se usaron entrevistas semiestructuradas que exploraban con detalle la historia de vida de los sujetos, incluyendo su consumo de drogas, redes sociales, contacto con instituciones, relaciones sexuales y estrategias de protección y vigilancia. Resultados La intencionalidad es importante para no infectarse, especialmente durante períodos de involución (períodos donde hay un deterioro económico y/o social que llevan al que se inyecta a situaciones de mayor riesgo). Presentamos tres dimensiones independientes de intencionalidad que conllevan comportamientos que pueden ayudar a prevenir la infección: a) evitar «el mono» (síntomas de abstención) asegurando el acceso a la droga; b) «llevarlo bien» para no convertirse en un junkie y así evitar la «muerte social» y la falta de acceso a los recursos, y c) seguir sin

  5. Plasma diagnostics and device properties of AlGaN/GaN HEMT passivated with SiN deposited by plasma-enhanced chemical vapour deposition

    Energy Technology Data Exchange (ETDEWEB)

    Romero, M F; Sanz, M M; Munoz, E [ISOM-Universidad Politecnica de Madrid (UPM). ETSIT, Madrid (Spain); Tanarro, I [Instituto de Estructura de la Materia, CSIC, Madrid (Spain); Jimenez, A, E-mail: itanarro@iem.cfmac.csic.e [Departamento Electronica, Escuela Politecnica Superior, Universidad de Alcala, Alcala de Henares, Madrid (Spain)

    2010-12-15

    In this work, silicon nitride thin films have been deposited by plasma enhanced chemical vapour deposition on both silicon samples and AlGaN/GaN high electron mobility transistors (HEMT) grown on sapphire substrates. Commercial parallel-plate RF plasma equipment has been used. During depositions, the dissociation rates of SiH{sub 4} and NH{sub 3} precursors and the formation of H{sub 2} and N{sub 2} have been analysed by mass spectrometry as a function of the NH{sub 3}/SiH{sub 4} flow ratio and the RF power applied to the plasma reactor. Afterwards, the properties of the films and the HEMT electrical characteristics have been studied. Plasma composition has been correlated with the SiN deposition rate, refractive index, H content and the final electric characteristics of the passivated transistors.

  6. Prácticas de activismo audiovisual con objetivo de integración social: el caso del colectivo Cine sin Autor (CsA

    Directory of Open Access Journals (Sweden)

    Ana María Sedeño Valdellós

    2016-03-01

    Full Text Available En los últimos años viene produciéndose una cierta tendencia hacia el empleo de la tecnología audiovisual por parte de colectivos activistas: con un objetivo transformador de realidades, las prácticas de activismo audiovisual se han enfocado a propiciar el empoderamiento de colectivos sociales como generadores de universos simbólicos propios. El texto reflexiona sobre el audiovisual como integración social desde un enfoque generalista y atendiendo a sus precedentes. En primer lugar, se comienza una exploración teórica sobre el concepto de activismo audiovisual y sus posibilidades educativas, activistas y para la integración social; en segundo lugar, se aborda un análisis en torno al trabajo del colectivo Cine sin Autor (CsA que, con una metodología participativa, construye “procesos audiovisuales abiertos” con comunidades y colectivos desfavorecidos.

  7. Culture of white shrimp (Litopenaeus vannamei Boone, 1931 with zero water exchange and no food addition: an eco-friendly approach Cultivo de camarón blanco (Litopenaeus vannamei Boone, 1931 sin recambio de agua y sin adición de alimento formulado: un sistema amigable con el ambiente

    Directory of Open Access Journals (Sweden)

    Juan Manuel Audelo-Naranjo

    2012-07-01

    Full Text Available Juveniles (3.5 ± 0.3 g of the white shrimp Litopenaeus vannamei were grown during 40 days with no water exchanges, no food addition and four initial densities (25, 50, 75 and 100 g m-3, corresponding to between 8 and 32 shrimp m-2, to determine growth rates, which could be achieved using the periphyton growing on artificial substrates as the only food source. The experimental culture units were 12 polyethylene 1 m³ cylindrical tanks with 4.8 m² of total submerged surface (bottom and walls, provided with 7.2 m² of artificial substrate (Aquamats™. There were no significant differences in the ammonia and nitrite concentrations determined in the four treatments (0.17-0.19 and 0.10-0.11 mg L-1, respectively, which remained below the respective levels of concern for shrimp cultures. Mean survival was similar, and ranged from close to 91 to 97%, whereas there were significant differences in mean individual weight, which ranged from 11.9-10.6 g shrimp-1 for the two low initial densities (25 y 50 g m-3, to 8.3-7.7 g shrimp-1 for the other treatments. However, because of the high survival and of the higher initial density, the best biomass yield was with 100 g m-3. The final nitrogen contents of sediment and water were lower than the initial values, and between 36 and 60% of the difference was converted into shrimp biomass.Durante 40 días se cultivaron juveniles de camarón blanco Litopenaeus vannamei con un peso individual de 3,5 ± 0,3 g y biomasas iniciales de 25, 50, 75 y 100 g m-3 (equivalente a 8-32 ind m-2, sin cambios de agua y adición de alimento, para determinar la tasa de crecimiento usando como única fuente de alimentación el perifiton desarrollado en sustratos artificiales. Se utilizaron estanques cilíndricos de polietileno de 1 m³ con tres réplicas por tratamiento, con una superficie de 4,8 m² (paredes y fondo y 7,1 m² de sustrato artificial (Aquamats™. No se encontraron diferencias significativas entre las concentraciones

  8. “De pugna virtutum adversus vitia”: os pecados capitais na obra de Isidoro de Sevilha = The cardinal sins in the work of Isidore of Seville

    Directory of Open Access Journals (Sweden)

    Sergio Alberto Feldman

    2010-07-01

    Full Text Available A proposta deste artigo é analisar a concepção dos pecados capitais na produção de Isidoro de Sevilha, a partir de sua obra magna o “Livro das Sentenças”, na qual descreve sua visão de mundo, sob a ótica da Cristandade e da teleologia agostiniana. O foco central éa construção de uma sociedade cristã que almeja combater o mal encarnado no diabo e em seus aliados, pela extirpação do pecado e pela construção de uma vanguarda de fiéis que se engajariam na luta das virtudes contra os vícios. O eixo da saúde pública permeia esseprojeto que visa a atingir a redenção e a segunda vinda de Cristo sob o Milênio redentor. The purpose of this paper is to analyze the conception of the cardinal sins in the work of Isidore of Seville, from his magnum opus "The Book of Sentences," which describes his world’s vision from theperspective of Christianity and Augustinian teleology. The main focus is the building of a Christian society that aims to combat evil in the devil incarnate and its allies through the removal of sin and the construction of a vanguard of believers who would engage in thestruggle of virtue against vices. The axis of this public health project aims to achieve the redemption and the second coming of Christ in the redeemer Millennium.

  9. Comportamiento del Intervalo QT corregido prolongado en el síndrome coronario agudo, sin elevación del segmento ST

    Directory of Open Access Journals (Sweden)

    Amauris Modesto Valera Sales

    2015-12-01

    Full Text Available Se realizó un estudio descriptivo transversal prospectivo, para determinar el comportamiento del intervalo QT corregido prolongado, en pacientes con síndrome coronario agudo sin elevación del segmento ST, en el Centro Diagnóstico Integral “Los Arales”, San Diego, año 2009. El universo fue de 48 pacientes y la muestra incluyó a 29 pacientes con ECG normal o sin nuevos cambios isquémicos. Al ingreso se determinaron los valores del intervalo QT corregido, las variables demográficas, antecedentes personales, niveles enzimáticos de CK-MB y el score TIMI. Estos resultados se correlacionaron con la aparición de eventos clínicos (muerte, infarto no fatal y revascularización un mes después del ingreso. De los 29 pacientes analizados sólo 11 (38% presentaron eventos clínicos, mientras que los restantes 18 (62% no los tuvieron. Los pacientes con eventos presentaron valores del iQTc más prolongados por encima del punto de corte. En ambos grupos predominó el sexo masculino y el grupo de edad más frecuente fue el de 60 a 69 años. El tabaquismo, la hipertensión y la hipercolesterolemia fueron los más prevalentes para ambos grupos, así como el uso previo de aspirina. La estratificación de riesgo TIMI y los parámetros basales en los pacientes estudiados fueron mayores y revelan un mayor porcentaje en el grupo con eventos clínicos. Los resultados demuestran que el iQTc predice eventos adversos cardiovasculares hasta 30 días después del ingreso.

  10. La fórmula del cuerpo sin órganos una aproximación Bergsoniana a su enunciación

    Directory of Open Access Journals (Sweden)

    Miguel Ruiz Stull

    2011-01-01

    Full Text Available Tomada desde Artaud por Deleuze ya desde la redacción de Lógica del sentido (1969, la expresión de cuerpo sin órganos (CsO no deja de causar al menos perplejidad. En su enunciación se traman puntos cruciales de la filosofía de Deleuze desde su teoría del acontecimiento y de la diferencia, pasando por una definición y una analítica del deseo, hasta una determinada noción de vida que articularía el proceso de su generación. Sin desestimar lo anterior y los profusos usos y determinaciones actuales que ha cobrado esta noción, nuestro propósito es vincular al CsO con la concepción de vida, que según nuestra lectura, se halla en la base de su formulación. Esto permanece en el texto como subyacente, y nuestra propuesta se inscribe en determinar el grado de influjo que posee el vitalismo de Bergson en la concepción de esta fórmula: desde este punto de vista es plausible sostener que el CsO es una operación que se funda de modo crucial en una lectura atenta al élan vital de bergsoniano. En suma, si el CsO es una involución creadora por definición de su proceso, no es sino porque su puesta en marcha significa y se efectúa en una constante y radical lucha que implica cada vez el desmontaje o desmembramiento de la idea de organismo.

  11. Variación espacio-temporal de plantas vasculares acuáticas en el complejo cenagoso del bajo Sinú, Córdoba, Colombia

    Directory of Open Access Journals (Sweden)

    Nabi Del Socorro Pérez-Vásquez

    2015-09-01

    Full Text Available Se determinó la variación espacio temporal de las plantas vasculares acuáticas en las ciénagas de María Arriba, San Sebastián, Purísima y Momil del complejo cenagoso del bajo Sinú (CCBS, en el departamento de Córdoba (Colombia, abarcando los periodos hidrológicos ocurridos durante el año 2011. El área de estudio se dividió en cuatro sectores y mediante el método de intercepción en línea se determinó la abundancia y frecuencia de las hidrófitas. En cada sector se extendió una línea de 200 m perpendicular al litoral y sobre ella se ubicaron cuadrantes de 1 m2 cada 50 m, en los que, se determinó la cobertura y frecuencia de las diferentes especies  Se registraron 39659 individuos distribuidos en 24 familias, 30 géneros y 35 especies. La mayor abundancia de especies se presentó en Momil con 18582 individuos, siendo la familia Lemnaceae la más representativa. El análisis de varianza (ANOVA indica que no existen diferencias estadísticas significativas en la abundancia de la especies de plantas acuáticas de los  meses de muestreo (F=1,04; GL=11; p = 0,083, sin embargo, se evidenció la incidencia del período hidrológico sobre la dinámica de crecimiento de las plantas, algunas especies desaparecen en época seca, otras sobreviven un periodo corto de tiempo, mientras que otras como Lemna minor L y Salvinia auriculata Aubl aumentan en época de lluvia.

  12. Influencia de costos totales en los presupuestos de ventas en MYPEs confeccionistas textiles en Los Olivos 2016

    OpenAIRE

    Guevara Hermoza, Luis Alberto

    2017-01-01

    Esta investigación tiene el interés de demostrar la influencia de los costos totales en el presupuesto de ventas de productos terminados en las empresas MYPEs textiles de confecciones. Estas empresas son dirigidas por sus dueños quienes no cuentan o tienen escasa formación para los negocios y, en consecuencia, enfrentan problemas sin herramientas adecuadas para resolverlos. Usualmente cuando el director de la MYPE se encuentra con poco efectivo o sus ganancias son muy reduci...

  13. Procedencia en la configuración de contratos atípicos en la nación-superintendencias sin personería jurídica y la nación-unidades administrativas especiales sin personería jurídica sujetas al estatuto de contratación estatal

    OpenAIRE

    Yucuma Carvajal, Catalina María

    2012-01-01

    Desde la introducción del postulado de la “autonomía de la voluntad” en el Estatuto de Contratación Estatal, es posible afirmar que trajo consigo grandes cambios, los cuales se ven reflejados en varios escenarios de la contratación y que sin lugar a duda revelan suma importancia, pero cuando nos referimos a la tipología contractual, primer estadio al cual deben enfrentarse las partes al momento de contratar, este postulado toma real trascendencia al proporcionar libertad a los contratantes, t...

  14. Interpretácie hriechu v židovskej literatúre v intertestamentárnom období (The Interpretation of the Sin in Judaic Literature and Intertestamentary Period

    Directory of Open Access Journals (Sweden)

    Sidonia Horňanová

    2008-03-01

    Full Text Available The aim of the contribution is to acquaint with the issue of origin of evil in the documents of intertestamentary period (the books of Enoch, the Book of Jubilees, Ben Sira and some texts from Qumran. Between the Testaments there was a very lively debate on the origin of sin. There was triple solving of the problem: Through interpretation of mythic account of the origin of evil of the agency of fallen angels; through interpretation of transmission of sin from Adam in paradise and finally through explanation of origin of evil in the Instruction on the Two Spirits in Qumran. In the present in Christian tradition there is the emphasis put on the hereditary transmission of sin from Adam.

  15. A method for determination of X-ray elastic constants of materials showing non-linear sin2ψ diagrams and its application to Zn-Ni-alloy electroplate

    International Nuclear Information System (INIS)

    Sasaki, Toshihiko; Kuramoto, Makoto; Yoshioka, Yasuo.

    1990-01-01

    This paper describes the method and the experiment for the determination of the x-ray elastic constants of Zn-Ni-alloy electroplate. For this material, the sin 2 ψ method is not adequate to use because this material shows severely curved sin 2 ψ diagrams. Therefore, a new method developed by the authors was explained first. This new method is effective for materials showing nonlinear sin 2 ψ diagrams. Secondly, the experiment was made on the application of this method to the Zn-Ni-alloy electroplate. And it was found out that the experimental data agreed well to the theory of this method. As a result, the following values were obtained as the x-ray elastic constants of the sample measured: (1+ν)/E=8.44 TPa -1 ν/E=2.02 TPa -1 (author)

  16. Arte sin mirada, arte sin emoción

    OpenAIRE

    Eraso Fernández, Elena

    2013-01-01

    En la presente propuesta educativa de carácter empírico se realiza un análisis experimental sobre la efectividad de la imagen a través de diferentes lecturas de la obra de arte, para lograr el desarrollo de capacidades emocionales y disfrute en educación secundaria. Se trata de una investigación apoyada en dos pilares fundamentales: la imagen artística, y las diferentes lecturas que se realizan de una obra de arte, para desarrollar sentimiento y deleite en el alumnado. Máster Universitario...

  17. Total Petroleum Hydrocarbons (TPH): ToxFAQs

    Science.gov (United States)

    ... a state: This map displays locations where Total Petroleum Hydrocarbons (TPH) is known to be present. On ... I get more information? ToxFAQs TM for Total Petroleum Hydrocarbons (TPH) ( Hidrocarburos Totales de Petróleo (TPH) ) August ...

  18. Grado de información, acceso y prácticasde elaboración de alimentos sin TACC de beneficios del programa de Asistencia Alimentaria para Celíacos de General Madariaga

    OpenAIRE

    Chaparro, María Victoria

    2015-01-01

    La Enfermedad Celíaca, también conocida como esprúe celíaco o enteropatía sensible al gluten, se la define como la intolerancia alimentaria de orden genético más frecuente de la especie humana. El único tratamiento es una dieta estricta y de por vida Sin TACC. La incidencia es mayor en mujeres, que en varones, siendo su prevalencia aproximadamente el 1% de la población. Objetivos: Determinar el grado de información, el acceso y las prácticas de elaboración de alimentos Sin T...

  19. Does Glycosylation as a modifier of Original Antigenic Sin explain the case age distribution and unusual toxicity in pandemic novel H1N1 influenza?

    Directory of Open Access Journals (Sweden)

    Nishiura Hiroshi

    2010-01-01

    Full Text Available Abstract Background A pandemic novel H1N1 swine-origin influenza virus has emerged. Most recently the World Health Organization has announced that in a country-dependent fashion, up to 15% of cases may require hospitalization, often including respiratory support. It is now clear that healthy children and young adults are disproportionately affected, most unusually among those with severe respiratory disease without underlying conditions. One possible explanation for this case age distribution is the doctrine of Original Antigenic Sin, i.e., novel H1N1 may be antigenically similar to H1N1 viruses that circulated at an earlier time. Persons whose first exposure to influenza viruses was to such similar viruses would be relatively immune. However, this principle is not sufficient to explain the graded susceptibility between ages 20 and 60, the reduced susceptibility in children below age 10, and the unusual toxicity observed. Methods We collected case data from 11 countries, about 60% of all cases reported through mid-July 2009. We compared sequence data for the hemagglutinin of novel H1N1 with sequences of H1N1 viruses from 1918 to the present. We searched for sequence differences that imply loss of antigenicity either directly through amino acid substitution or by the appearance of sites for potential glycosylation proximal to sites known to be antigenic in humans. We also considered T-cell epitopes. Results In our composite, over 75% of confirmed cases of novel H1N1 occurred in persons ≤ 30 years old, with peak incidence in the age range 10-19 years. Less than 3% of cases occurred in persons over 65, with a gradation in incidence between ages 20 and 60 years. The sequence data indicates that novel H1N1 is most similar to H1N1 viruses that circulated before 1943. Novel H1N1 lacks glycosylation sites on the globular head of hemagglutinin (HA1 near antigenic regions, a pattern shared with the 1918 pandemic strain and H1N1 viruses that circulated

  20. Disponibilidad de agua, nitrógeno y azufre en barbechos con y sin control de malezas en distintos niveles de residuos Water, nitrogen and sulphur availability in fallows with and without weed control and different residue levels

    Directory of Open Access Journals (Sweden)

    Romina Fernández

    2009-06-01

    Full Text Available Con el fin de evaluar el efecto de los residuos vegetales sobre la eficiencia de almacenamiento de agua, la dinámica de nitrógeno y azufre disponible durante el barbecho con y sin presencia de malezas, se realizaron 10 ensayos con distintos niveles de residuos (A: 10.000 kg MS ha-1, M: 5.000 kg MS ha-1, B: menor a 2.000 kg MS ha-1 en Haplustoles de las regiones planicie con tosca y planicie medanosa de La Pampa y Sur de Córdoba. En cada tratamiento de residuos se dividieron las parcelas en dos subtratamientos de manejo de malezas: tratamiento con malezas (malezas y sin malezas (barbecho. Se realizaron determinaciones de: textura, densidad aparente, punto de marchitez permanente, materia orgánica total. Al inicio y al final del barbecho se midió el contenido de agua en el suelo, nitratos (N, azufre de sulfatos solubles y adsorbidos (S en 0-0,2 m de profundidad. Al comienzo del barbecho todos los sitios presentaron altos contenidos de agua útil (entre 51 y 100%. A pesar de ello, nuestros resultados mostraron que al finalizar el barbecho el nivel de residuos tuvo un efecto positivo en los contenidos de agua con una diferencia entre A y B de 33%. Con presencia de las malezas, no se pudo comprobar una ventaja por parte de los residuos y la diferencia entre A y B fue de 10%. El factor que más influyó en los contenidos de agua fue la presencia de malezas. Los contenidos de N y de S disponible no fueron influenciados por los distintos niveles de residuos, constatándose un mayor efecto de malezas. En el tratamiento con malezas se vería comprometida la siembra del cultivo de girasol por menor disponibilidad de agua y además se afectaría el rendimiento en 200 kg ha-1 por la menor disponibilidad de N y en 600 kg ha-1 por menor disponibilidad de S disponible en el nivel A de residuos.In order to study the effect of crop residues on the efficiency of water storage, available nitrogen and sulphate dynamics during fallow with and without weed