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Sample records for tooman joachim fendt

  1. The Role of FENDT - Prospect and Retrospect -

    International Nuclear Information System (INIS)

    Lee, Hae

    1998-01-01

    Being latecomers to the industrialization, Pacific rim countries except the U.S.A. are doing very little in developing the universal certification system. One should note that Asian Pacific region enjoys the highest economic growth rate, and there is a good possibility that it will be the center of economic activities of the world in the next century. It appears that ISO and CEN share similar specifications in numerous areas. ASNT is being changed to cope with the trend with the introduction of ACCP. Although we may have to adopt the new system someday, we should pay attention and make concerted effort to include our own practice in the global standards. We are the countries in the Far East Region with similar culture and tradition, which are quite different from those of western countries. We hope that Japan should play an important role in this matter, who has been chaired the ISO TC135 since 1993. In the beginning of this decade, there has been a trivial but troublesome matter that who is representing the NDT Society or member countries in Asia-Pacific Conference on NDT. The problem appears to be solved since the establishment of FENDT For the next decade, actually next century, FENDT will have to accomplish another important role for countries in the Far East Region to form a strong coalition for its survival in the western dominant world. Immediate issue is to establish Far East Working Group for Harmonization and Mutual Recognition of Qualification and Certification of NDT Personnel. To realize this Japan must play a leading role with the cooperation of expanded FENDT member countries including China and Russia. As the continued prosperity expected in this region, FENDT should continue its role for the next century. We, the FENDT countries, must move forward for internationalization. However' we must realize that it all start from SELF IDENTI-FICATION. We can identify ourselves by actively participating in FENDT. I would like remind you the concluding remark

  2. Hans-Joachim Schlieben , collector extraordinary

    Directory of Open Access Journals (Sweden)

    O. A. Leistner

    1976-11-01

    Full Text Available Hans-Joachim Eberhardt Schlieben was born in Germany in 1902. Between 1930 and 1935 he collected plants in Tanzania and since 1955 in Southern Africa, on Madagascar, the Mascarenes, the Comoro Islands and the Seychelles. Almost 400 of the approximately 13 000 numbers which he has collected have been described as new.

  3. Joachim Tückmantel (1948 - 2013)

    CERN Multimedia

    2013-01-01

    The news of the sudden death of Joachim Tückmantel on 7 December 2013 filled us, his colleagues and friends, with immense grief and deep sadness. He passed away shortly after retiring from CERN where he worked for 40 years.   Joachim joined CERN in 1973 and made significant contributions to the design and understanding of particle accelerators. From the start, he was involved with superconducting RF technology and performed pioneering work for the LEP and PETRA cavities. In particular, he invented the DC bias to prevent the multipactor effect in the LEP2 RF system; this was essential for the success of LEP2. He authored the Semi Analytic Processor (SAP), the core of many electromagnetic simulation codes. He was equally expert in impedances and wake fields, and the mitigation of their effect. Joachim was also a respected authority for both technology and simulation of RF systems, and his advice was sought out for many accelerators at CERN and worldwide. He made important contribution...

  4. The Intimacy of Internationalism in the Poetry of Joachim Sartorius

    Directory of Open Access Journals (Sweden)

    Neil H. Donahue

    1997-01-01

    Full Text Available This article considers Joachim Sartorius in his various cultural and literary activities as diplomat, administrator, editor, translator, and poet as a possible model for the German intellectual after reunification, and links those activities through the concept of "internationalism," which has shifted in meaning from programmatic politics to an understanding of cultural difference and mediation with an Other, whether as public and private spheres, Self and Other, or Subject and Object. For Sartorius, however, poetry defines most closely or most intimately that notion of mediation, and thus requires 'close' reading. That notion distances him from the 'impersonal' Modernist poetics of Bertolt Brecht and Gottfried Benn, and links him internationally to W. C. Williams and Pierre Jean Jouve. By examining that connection, this essay defines the international and philosophical base for Sartorius's poetics of intimacy.

  5. DIE PFLANZENSAMMLUNG VON JOACHIM WATTENDORFF (1928-2008) IM HERBARIUM MÜNSTER (MSTR)

    DEFF Research Database (Denmark)

    Baden, Maria; Tenbergen, Bernd

    2014-01-01

    The complete collection of Swiss professor of botany Joachim Wattendorff, born in the small Westphalian town of Borghorst, consists of more than 5,000 samples, considerably enriching the Herbarium (MSTR) in the LWLMuseum für Naturkunde (Museum of Natural History) in Münster, Germany. Over the past...

  6. Blank ja Jeron (sero.org) / Joachim Blank, Karl Heinz Jeron ; interv. Tilman Baumgärtel

    Index Scriptorium Estoniae

    Blank, Joachim

    2006-01-01

    Nime sero.org all esinenud saksa kunstnikepaarist Joachim Blankist (sünd. 1963) ja Karl Heinz Jeronist ning nende loomingust, intervjuu kunstnikega nende Berliini ateljees 10. II 2000. Saksa võrgukunsti edendamisest rühmituste Lux Logis, Handshake ja Internationale Stadt koosseisus, jututubadest, teostest "Dump your trash", "Re-M@il", installatsioonidest "re: represent", "Scanner +++", "sign.post" ja muust

  7. Why There Are Certain Parallels Between Joachim C. Fest’s Hitler-Biography and Michael Wolff’s Trump-Book

    Directory of Open Access Journals (Sweden)

    Christian Fuchs

    2018-02-01

    Full Text Available Joachim C. Fest published one of the most widely read Hitler biographies in 1973. Are there parallels of its analytical approach to Michael Wolff’s “Fire and Fury: Inside the Trump White House”?

  8. "Forgotten" Chapters in the History of Transcervical Sterilization: Carl Clauberg and Hans-Joachim Lindemann.

    Science.gov (United States)

    Hildebrandt, Sabine; Benedict, Susan; Miller, Erin; Gaffney, Michael; Grodin, Michael A

    2017-07-01

    Transcervical sterilization is a non-surgical method of permanent female sterilization that is widely used and critically discussed. A review of the historiography of the method reveals that instances of its coercive use are not included in the historical account. This study offers a reexamination of the work of Carl Clauberg and Hans-Joachim Lindemann, to more deeply contextualize within the framework of current usage the coercive use of transcervical sterilization during the Third Reich and in postwar Germany. This inquiry is based on postwar criminal trial records on Clauberg, and on archival documents detailing Lindemann's activities in 1979. A comparative analysis examines arguments by medical historian Karl-Heinz Roth, and identifies shared characteristics and differences between Clauberg and Lindemann, their methods and scientific connections. The results demonstrate that the technique of transcervical sterilization has an abusive potential that may be explained as a function of the person of the physician, of the scientific method itself, and of societal and political influences. The analysis supports the argument that insights from the cases of Clauberg and Lindemann are transferrable geographically and over time, and have the potential to inform current medical practice, such as transcervical sterilization with the Essure device, whose historiographic exploration remains a desideratum. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  9. "Kommentar zu „Ableitung von Korngrößenverteilungen aus textbasierten petrografischen Bohrgutbeschreibungen“ von Michael Naumann, Anja Waldeck, Wolfgang Poßin, Carsten Schwarz & Joachim Fritz (Z. Dt. Ges. Geowiss., 165/2: 275–286)"

    DEFF Research Database (Denmark)

    Fuchs, Sven

    2015-01-01

    Fuchs, S. (2015): Kommentar zu „Ableitung von Korngrößenverteilungen aus textbasierten petrografischen Bohrgutbeschreibungen“ von Michael Naumann, Anja Waldeck, Wolfgang Poßin, Carsten Schwarz & Joachim Fritz (Z. Dt. Ges. Geowiss., 165/2: 275?286). [Comment on “Deduction of grain size distributions...... based on petrographic borehole descriptions” by Michael Naumann, Anja Waldeck, Wolfgang Poßin, Carsten Schwarz & Joachim Fritz (Z. Dt. Ges. Geowiss., 165/2: 275?286).] – Z. Dt. Ges. Geowiss....

  10. Hans-Joachim Koenig. En el camino hacia la nación. Nacionalismo en el proceso de la formación del Estado y de la nación de la Nueva Granada, 1750-1856

    Directory of Open Access Journals (Sweden)

    Dagmar Kusche

    1993-01-01

    Full Text Available Hans-Joachim Koenig. En el camino hacia la nación. Nacionalismo en el proceso de la formación del Estado y de la nación de la Nueva Granada, 1750-1856. Bogotá: Editorial del Banco de la República, 1994. 562 páginas.

  11. Robert Schumann und die Öffentlichkeit. Hans Joachim Köhler zum 70. Geburtstag. Internationale musikwissenschaftliche Konferenz am Institut für Musikwissenschaft der Universität Leipzig, 15. - 16. 9. 2006

    Czech Academy of Sciences Publication Activity Database

    Gabrielová, Jarmila

    2007-01-01

    Roč. 44, č. 1 (2007), s. 93-95 ISSN 0018-7003. [Robert Schumann und die Öffentlichkeit. Hans Joachim Köhler zum 70. Geburtstag. Leipzig, 15.09.2006-16.09.2006] Institutional research plan: CEZ:AV0Z90580513 Keywords : Robert Schumann Subject RIV: AL - Art, Architecture, Cultural Heritage

  12. [Criminal process record Winckelmann (Triest, 1768). Comments on the criminal process dealing with the murder of Johann Joachim Winckelmann from the forensic historical and legal medicine viewpoint].

    Science.gov (United States)

    Risse, M; Weiler, G

    2001-01-01

    Johann Joachim Winckelmann, German historian of ancient art and archaeologist, was born on 9 December 1717 in Stendal, a town in Saxony-Anhalt. At the age of 50 he was murdered on 8 June 1768 in a Trieste hotel. The voluminous original record of the criminal proceedings against his murderer, Francesco Arcangeli, was presumed lost for about 150 years. A new edition in the wording of the original text appeared in 1964. This long sought historical document gives cause for forensic-historical reflections under consideration of the autopsy protocol about Winckelmann, which is likewise a historical document. A considerable change of paradigm in comparison to current autopsy protocols is observed with regard to the evaluation of injuries and the circumstances of death.

  13. Estonija otshen bogata / Artur Tooman

    Index Scriptorium Estoniae

    Tooman, Artur, 1971-

    2008-01-01

    Eesti fosforiidivarud ulatuvad erinevatel hinnangutel 3-8 miljardi tonnini. Fosforiidi kaevandamise võimalustest, mineraalväetiste tootmisest Eestis. Kommenteerivad Anto Raukas, majandusminister Juhan Parts, Nikolai Kutashov, Alvar Soesoo ja Hallar Meibaum. Vt. samas: Väetiste hinnaprognoosid. Diagramm: Fosforväetiste hinna muutused

  14. Biogaz raspolzajetsja po stranje / Artur Tooman

    Index Scriptorium Estoniae

    Tooman, Artur, 1971-

    2004-01-01

    Biogaasi tootmisest prügilates. Firma Terts AS-i projektist Pääsküla suletud prügilast tekkiva biogaasi kasutusele võtmiseks. Diagrammid: Tert AS majandusnäitajad; Elektri- ja soojusenergia müük

  15. Sotsiaalteenuste kvaliteedi hindamine ja kontroll / Heli Tooman

    Index Scriptorium Estoniae

    Tooman, Heli, 1949-

    2002-01-01

    Uurimisprojekti "Sotsiaalteenuste vajadus ja kasutamine - territoriaalsed, sotsiaalsed ja kultuurilised erinevused" raames katsetati SERVQUAL meetodit sotsiaalteenuste kvaliteedi mõõtmiseks Pärnu ja Narva sotsiaalasutustes. Tabelid. Bibliogr.

  16. Uus Euroopa - uued turismisihtkohad / Heli Tooman

    Index Scriptorium Estoniae

    Tooman, Heli, 1949-

    2008-01-01

    21.-23. maini Sloveenias toimunud rahvusvahelise turismikonverentsi "New Europa - New Destinations" läbivaks teemaks oli Euroopa uute turismisihtkohtade väljakutsed ning võimalused. Ülevaade professorite Tom Baumi, David Airey, Nigel Hemmingtoni ja Jay Kandampully ettekannetest

  17. Bogatstva Estonii pod spudom / Artur Tooman

    Index Scriptorium Estoniae

    Tooman, Artur, 1971-

    2001-01-01

    Teravmägede sügavuses võib spetsialistide hinnangul olla kivisütt, fosforiiti, mäekristalli, isegi kulda ja hõbedat. Pariisi rahvusvahelise lepingu (1920.a.) kohaselt on kõigil selle lepinguga ühinenud riikidel, ka Eestil, võrdsed õigused kasutada Teravmägedes leiduvaid maavarasid

  18. Ossipenko vplotnuju vzjalsja za Narvu / Artur Tooman

    Index Scriptorium Estoniae

    Tooman, Artur, 1971-

    2008-01-01

    Ajakirjanduses Narva linna halliks kardinaliks nimetatud Aleksandr Moissejevit süüdistatakse altkäemaksu andmises. Tähelepanuta jäänud kaadrimuudatustest Narva linnavalitsuses. Vt. samas: Narva võtab krediiti; Väited, et tegemist on võimuvõitlusega

  19. Trotz Richtlinie weiterhin intergouvernmental / Joachim Lippott

    Index Scriptorium Estoniae

    Lippott, Joachim

    2017-01-01

    ELi kodanike konsulaarkaitsest kolmandates riikides rahvusvahelise, Euroopa Liidu ja siseriikliku õiguse aspektist; ELi toimimise lepingu artikli 23, diplomaatiliste suhete ja konsulaarsuhete Viini konventsiooni tõlgendamisest

  20. 948-IJBCS-Article-Joachim D Gbenou

    African Journals Online (AJOL)

    DR GATSING

    Sterculia setigera, Aframomum melegueta et Citrus aurantifolia sont des plantes couramment utilisées en médecine et pharmacopée traditionnelles africaines pour traiter plusieurs affections dont la toux et l'asthme. L'objectif du présent travail est d'évaluer, sur Cavia porcellus (Cochon d'Inde), les propriétés ...

  1. [Georg Joachim Rhetikus, between Paracelsus and Copernicus].

    Science.gov (United States)

    Burmeister, K H

    2000-01-01

    At first the author presents the familial background of Rheticus, then his education, his friendships and scientific contacts. Rheticus was professor of university in Wittenberg and Leipzig. Most interesting were his contacts with Paracelsus and Copernicus. Last two decades of life Rheticus spent in Cracow working as a physician and mathematician. He died in Kosice.

  2. Dano tseu speshno sozdat TsU / Artur Tooman

    Index Scriptorium Estoniae

    Tooman, Artur, 1971-

    2007-01-01

    Narvas luuakse veel üks tööstuspark - Narva Tööstusala Arendus SA, mida finantseeritakse linna eelarvest ja Euroopa fondidest. Sihtasutus hakkab 100protsendiliselt kuuluma linnale. Vt. samas: Ida-Virumaa tööstuspargid investeerivad kümneid miljoneid

  3. Za rubezhom nashi bezrabotnõje - k mestu / Artur Tooman

    Index Scriptorium Estoniae

    Tooman, Artur, 1971-

    2003-01-01

    Tööpuudust aitaks osaliselt leevendada töötamine välisriikides. Sotsiaalministeeriumis valmistatakse ette spetsialiste, kes hakkavad edastama infot ja vajadusel vormistama dokumente Euroopa Liidu riikidesse tööleminejatele

  4. Estonian-bound Russian timber detours through Latvia / Artur Tooman

    Index Scriptorium Estoniae

    Tooman, Artur, 1971-

    2002-01-01

    Ilmunud ka: Baltiiskii Kurss 2002/Zima/Vesna nr. 20 lk. 29. Venemaa tollikomitee otsus, mis ei lubanud ühegi Eesti piiripunkti kaudu Vene metsa Eestisse eksportida, seab paljud metsaga kaubitsejad ning metsatöötlejad keerulisse olukorda. Diagramm

  5. Tres chalets de Joachim Schürmann

    Directory of Open Access Journals (Sweden)

    Schürmann, Joachim

    1974-12-01

    Full Text Available This article describes three one family houses; one in Dublin, one for professor Lehmann-Grube and another one in Rosenhohe (Darmstadt. In its outer aspect as well as interior decoration the materials used and the planning are completely different, which corresponds to the different characters of those who live in them, at the same time as they emphasize the flexibility and the excellent work of the architect.En este artículo se describen tres viviendas unifamiliares: una en Dublin, otra para el Dr. Lehmann-Grube y otra en la Rosenhohe (Darmstadt. Tanto su fisonomía exterior como el tratamiento interior, los materiales empleados y la distribución adoptada son completamente diferentes, cual corresponde a la distinta idiosincrasia de sus moradores, a la vez que nos hacen patente la flexibilidad y buen hacer del arquitecto.

  6. Neudatshnõi opõt - poleznõi opõt / Artur Tooman

    Index Scriptorium Estoniae

    Tooman, Artur, 1971-

    2007-01-01

    OÜ Eesti Tubakas investeeris OÜ Innovative Pack Systeme abil 3 miljonit dollarit sigaretitehase seadmetesse, et suurendada tootmist, kuid turunduspartner Greenfield Tobacco loobus täitmast oma kohustusi ja taganes oma lubadustest realiseerida toodang Aafrika turul. Diagramm: Innovative Pack Systeme OÜ majandusnäitajad

  7. Karastusjoogihiid võib Eestile selja pöörata / Virge Lahe, Artur Tooman

    Index Scriptorium Estoniae

    Lahe, Virge

    2008-01-01

    Coca-Cola kolib kulude optimeerimiseks oma tootmise Tallinnast Lätti. Vt. samas: Õlletehas jätkab Sakus; Farmaatsiatehas võib kolida Riiga; Coca-Cola Hellenic. Diagramm: Coca-Cola majandusnäitajad

  8. Rõbolovõ hotjat zanimatsja proizvodstvom file i konservov / Artur Tooman

    Index Scriptorium Estoniae

    Tooman, Artur, 1971-

    2003-01-01

    Kohalikel kaluritel ei ole majanduslikult tulus kala püüda, seetõttu plaanivad paljud ise ka kalatöötlemisega tegeleda. Tabel: Kala ümbertöötlevate ettevõtete arv, kala eksport/import, kalapüügi maht. Statistika

  9. VocMat projekt - uudsed e-õppe võimalused turismiasjalistele / Heli Tooman

    Index Scriptorium Estoniae

    Tooman, Heli, 1949-

    2008-01-01

    Turismivaldkonna spetsialistidele mõeldud koolitusprojektist VocMat (Vocational Management Training for the Tourism Industry). Projekti partneriteks Eestis on Ettevõtluse Arendamise Sihtasutuse Turismiarenduskeskus ja Tartu Ülikooli Pärnu kolledzh. Lisa: Kokkuvõte

  10. Joachim Heinrich Campe’s Robinson the Younger: Universal Moral Foundations and Intercultural Relations

    Directory of Open Access Journals (Sweden)

    Claudia Nitschke

    2016-06-01

    Full Text Available In his adaptation of Robinson Crusoe, Campe sets out to examine the legitimacy of his contemporary social reality (in Europe in the broadest sense by tracing its origin back to the most basic roots conceivable. The experimental character of his book is emphasised and—to an extent—explicitly introduced through the frame narrative which constitutes Campe’s most important addition to Defoe’s story: Here the emergence of the rules and routines are extensively mooted by the father (who relates Robinson’s story as a framed narrative and his children who still have to internalise, grasp, and situate the moral rules around them and frequently offer divergent perspectives in the process. The frame narrative connects the moral “ontogeny” of the children to the “phylogenetics” of civilisation and suggests that both can be superimposed on one another. I will work with concepts that focus on the differentiation between “innate” moral characteristics and their social transformation on a cognitive, evolutionary level, from which Campe clearly deviates. However, his short-circuiting of the individual and the phylogeny leads to very similar specifications as laid out by, for instance, Moral Foundations Theory.

  11. Prokofieff: Kantate zum 20. Jahrestag der Oktoberrevolution, Op.74, Neeme Järvi / Joachim Salau

    Index Scriptorium Estoniae

    Salau, Joachim

    1993-01-01

    Uuest heliplaadist "Prokofieff: Kantate zum 20. Jahrestag der Oktoberrevolution, Op.74, Auszüge aus Das Märchen von der steinernen Blume. Gennadij Roshdestwenskij (Sprecher), Philharmonia Chorus, Philharmonia Orchestra, Neeme Järvi. Chandos/Koch CD 9095

  12. Dos obras del Prof. Joachim Schürmann - Alemania Federal

    Directory of Open Access Journals (Sweden)

    Editorial, Equipo

    1974-06-01

    Full Text Available Parish Centre of St. Josepk, in Oer Erkenschwick. It includes: three buildings constructed in an architecture of simple lines and with a modern and functional appearance. The kindergarten, the church and the sacristy cum apartments of the parson and the sacristan are surrounded by gardens and situated in the most suitable spot of the site. The structure of the chapel is particularly interesting with flat reticular roofing supported by four pyramidal pillars. Convent of San Sebastian, Neuss. It has been constructed next to the old church and consists of an original convent and a spacious courtyard-garden which together with the kitchen, conference halls, library, conference rooms, dining room and recreation hall, sacristry and entrance constitute the lower floor. The rooms are located on the two floors above. The predominating material of the exterior and the interior is of unseen concrete, at times covered by a light layer of paint.Centro Parroquial de San José, en OerErkenschwick. Comprende: tres cuerpos edificados de una arquitectura a base de sencillas líneas y fisonomía de gran actualidad y funcionalismo. El jardín de infancia, la iglesia y la sacristía-viviendas del párroco y del sacristán, están rodeadas de zonas ajardinadas y situadas en el lugar más idóneo del solar. Es particularmente interesante la estructura especial de la capilla, con cubierta reticulada plana, agrupada sobre cuatro pilares piramidales. Convento de San Sebastian, en Neuss. Se ha construido junto a la antigua iglesia y consta de un original claustro y un amplio patio-jardín que, con la cocina, salas de coloquios, biblioteca, despachos, comedor y recreo, sacristía y entrada constituyen la planta baja. En las dos altas se distribuyen las habitaciones. El material dominante en exteriores e interiores es el hormigón visto, recubierto a veces por una ligera piel de pintura.

  13. Maastik : Esteetilise funktsioonist modernses ühiskonnas / Joachim Ritter ; tlk. Age Veeroos, saatesõna Ülo Matjus

    Index Scriptorium Estoniae

    Ritter, Joachim

    1996-01-01

    Loodus kui esteetiliselt vahendatud maastik: uusaja maailma kuulub loodus maastikuna, kusjuures luule ja kunst kordavad teaduse kaudu vahendatud 'objektiivset' loodust esteetiliselt. Ka Francesco Petrarca kirjast Francesco Dioginile Borgo San Sepolcrost ja Friedrich Schilleri luuletusest 'Jalutuskäik'

  14. Løssluppen kohærens i Fredmans säng nr. 41 "Joachim uti Babylon"

    DEFF Research Database (Denmark)

    Heltoft, Lars

    2015-01-01

    Denne artikel er ment som et bud på at løse visse problemer med forståelsen af FS (Fredmans Sång) 41 som en del af de bibelske travestier i værket. Den er samtidig et bidrag til udviklingen af tekstanalytisk praksis på grundlag af tæt sproglig analyse. Den er et eksempel på hvorledes tekstforståe...

  15. "Vaba ja sotsiaalne" kui õiguspõhimõte. [1.-2. osa] / Joachim Ruckert ; tõlkinud Marju Luts-Sootak

    Index Scriptorium Estoniae

    Ruckert, Joachim

    2008-01-01

    Sotsiaalsest õiglusest filosoofilisest aspektist ning "vaba ja sotsiaalse" probleemi lahendamisest. Tõlkeallikas: Würzburger Vorträge zur Rechtsphilosophie, Rechtstheorie und Rechtssoziologie, Heft 34. Baden-Baden, 2006

  16. 2 April 2014 - H. E. Mr Joachim Gauck, President of the Federal Republic of Germany in the ATLAS experimental cavern with Director-General R. Heuer.

    CERN Multimedia

    Brice, Maximilien

    2014-01-01

    in the ATLAS cavern: Minister of State at the Federal Foreign Office M. Böhmer (green jacket) and Mrs daniela Schadt (First Lady). 201404-069_39.jpg: State Secretary, Federal Ministry of Education and Research G. Schütte, Minister of State at the Federal Foreign Office M. Böhmer, President Gauck, CERN DG, State Secretary, Chief of the Federal President´s Office D. Gill and Ambassador of the Federal Republic of Germany to the Swiss Confederation O. Lampe.

  17. Pärnus toimus terviseturismi konverents / Toomas Undusk

    Index Scriptorium Estoniae

    Undusk, Toomas

    2013-01-01

    24. mail Pärnus toimunud konverentsist, kus esinesid Tiit Kask, Heli Tooman, Melanie Smith ja Laszlo Puczko Ungarist, Vladan Veškovič Serbiast, Anja Tuohino Soomest, Gunta Uspele Lätist ning Laimutis Paškevičius Leedust, Tiina Mikk, Aire Toffer, samuti toimus paneeldiskussioon terviseturismi arengutendentsidest Ain Hinsbergi modereerimisel

  18. ‘Introduction. Le mythe winckelmannien’ and ‘Première partie. Le culte du livre’ from Johann Joachim Winckelmann: Enquête sur la genèse de l'histoire de l'art

    Directory of Open Access Journals (Sweden)

    Elisabeth Décultot

    2010-06-01

    Full Text Available For his friends and for himself, Winckelmann likes to divide his life in two quite distinct periods: the German one at first, which unfolds in dark libraries, and then the Italian one, lived in the light of Rome’s art collections. In this construct, the Italian phase stands in contrast to the German one as sensible knowledge does to bookish learning. This dichotomy, which was stylized by Winckelmann himself, then picked up again by his biographers and interpreters, is doubly beneficial for him. It allows him first, in the order of autobiography, to set himself up as the hero of a dynamic tale marked by a strong existential split. In moving from Germany to Rome, Winckelmann could be seen to have lifted himself from the dead universe of books to the tangible reality of stone statues. But it allows him too to position himself as the founder of a new field of study: art history. With his Geschichte der Kunst des Altherthums (1764, written in Rome, the historical discourse about art, which — according to Winckelmann — up to then has rested on ancient texts, begins to rely on the sensible observation of works of art.An attentive reader, however, shouldn’t be content with such a construct. The use of books plays a much more complex role in Winckelmann’s life than what the Roman Winckelmann cares to admit. What, then, is the role of reading in Winckelmann’s work? What is the role of the book in the German and Italian phase of its development? An unusually rich archival collection is available to answer these questions: his notebooks of excerpts. Starting in his student years, Winckelmann developed the habit of recording entire text passages he read and thus constituting a portable handwritten library, which never left him. The result of this meticulous compilation work appears on approximately 7500 pages covered with fine, narrow handwriting, mostly preserved at the manuscript department of the Bibliothèque Nationale de France, in Paris. This tremendous collection raises many questions, on which the present book focuses :I. How did Winckelmann’s reading activity develop?II. How does this reading activity fit within the wider context of the scholarly tradition?III. What was its effect on the written composition of Winckelmann’s work, which is to say, its style, its structure and its theoretical content?

  19. Energy efficient technology - from this all will benefit; Energieeffiziente Technik - davon profitieren alle

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-02-15

    Within the International Trade Fair of Craft between 11th and 17th March, 2009 in Munich (Federal Republic of Germany) the Federal Ministry of Economics and Technology (Berlin, Federal Republic of Germany) presented the following lectures: (1) The handicraft in context to demography - The demography in the east German federal states (Thomas Satzmann); (2) The handicraft in the financial crisis (Joachim Garrecht); (3) The transformation of the service regulation (Thomas Ernst); (4) Future handicraft (Joachim Garrecht); (5) Journalist Special: Use of electronic media such as podcast and internet-TV for public relations in the handicraft (Michael Bachmann); (6) Standardization at small and medium-sized enterprises (Thomas Ernst); (7) Crafts and tourism (Evelin Friedrich); (8) The handicraft in the financial crisis (Joachim Garrecht); (9) Activation of facades in existing buildings in combination with air heat and solar thermal power - Theory and reports from the practice (Jens Wolfensteller, Volker Drexel); (10) Fiscal reform in favour of the handicraft (Joachim Garrecht, Johannes Hoefer); (11) The transformation of the service regulation (Thomas Ernst); (12) Mould fungus, dangerous subtenant - General aspects to mould fungi, recognition, health aspects and removal (Sabine Hoer); (13) The energy competency centre of the Chamber of Commerce Potsdam (Herbert Pape); (14) The handicraft in the financial crisis (Joachim Garrecht); (15) Standardization at small and medium-sized enterprises (Thomas Ernst); (16) Reformation of the inheritance tax (Joachim Garrecht, Johannes Hoefer); (17) Amendment of the law for chimneysweepers (Joachim Garrecht); (18) Future handicraft (Joachim Garrecht); (19) Handicraft and tourism (Evelin Friedrich); (20) Politics in favour of the handicraft (Joachim Garrecht); (21) Reformation of the inheritance tax (Joachim Garrecht); (22) Challenges of the demography in the handicraft (Evelin Friedrich); (23) The handicraft in the financial crisis

  20. Untitled

    International Development Research Centre (IDRC) Digital Library (Canada)

    . Asociación FaunAgua, Bolivia. Dr. Paul van Damme. Development of a model for comparable development elsewhere in the country. World Fisheries Trust, Canada. Dr. Joachim Carolsfeld. Improved contribution of small-scale aquaculture to ...

  1. ["Schleichwege" : inoffizielle Begegnungen sozialistischer Staatsbürger zwischen 1956 und 1989] / Oliver Pagel

    Index Scriptorium Estoniae

    Pagel, Oliver, 1984-

    2013-01-01

    Arvustus: "Schleichwege" : inoffizielle Begegnungen sozialistischer Staatsbürger zwischen 1956 und 1989. Hrsg. von Włodzimierz Borodziej, Jerzy Kochanowski, Joachim von Puttkamer. Böhlau Verlag. Köln, Weimar und Wien 2010

  2. Bandiiditarid jätkavad Robin Hoodi traditsiooni / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2006-01-01

    Action-komöödia "Bandidas" : režissöörid Joachim Roenning, Espen Sandberg : stsenarist ja produtsent Luc Besson : osades Salma Hayek, Penelope Cruz : Ameerika Ühendriigid - Mehhiko - Prantsusmaa 2006

  3. Bandiiditarid / Alar Niineväli

    Index Scriptorium Estoniae

    Niineväli, Alar

    2006-01-01

    Action-komöödia "Bandidas" : režissöörid Joachim Roenning, Espen Sandberg : stsenarist ja produtsent Luc Besson : osades Salma Hayek, Penelope Cruz : Ameerika Ühendriigid - Mehhiko - Prantsusmaa 2006

  4. Inglihääled vaiksel ööl / Loone Ots

    Index Scriptorium Estoniae

    Ots, Loone, 1965-

    2015-01-01

    Jõululaulust "Püha öö" ("Vaikne öö"), sõnade autor Joseph Franz Mohr, viisi autor Franz Xaver Gruber. Jõulukoraalist "Hõisake, taevad", autor Joachim Neander. Jõulukoraalist "Ma tulen taevast ülevalt", autor Martin Luther

  5. Liivimaa reformatsiooni poliitilised, religioossed ja sotsiaalsed aspektid / Juhan Kreem

    Index Scriptorium Estoniae

    Kreem, Juhan

    2007-01-01

    Rets. rmt.: Joachim Kuhles. Die Reformation in Livland - religiöse, politische und ökonomische Wirkungen. (Hamburger Beiträge zur Geschichte des östlichen Europa, 16). Verlag Dr. Kovaè, Hamburg, 2007. 363 lk.

  6. Letters & Arms Literary Language, Power and Nation in Renaissance Italy and France 1300-1600

    DEFF Research Database (Denmark)

    Toftgaard, Anders

    2005-01-01

    Sprog, litteratur, filologi, national identitet, Joachim Du Bellay, Jean Lemaire de Belges, Henri Estienne, Sperone Speroni, Pietro Bembo, Dante Alighieri, Frans den første (af Frankrig), Anthony D. Smith, Liah Greenfeld...

  7. Physicists bag Chemistry Nobel for microscopy method

    Science.gov (United States)

    Johnston, Hamish

    2017-11-01

    The 2017 Nobel Prize for Chemistry has been given to Jacques Dubochet, Joachim Frank and Richard Henderson “for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution”.

  8. Raamat ainsana maailmas Tallinnas säilinud 16. sajandi käsikirjast / Vello Lumiste

    Index Scriptorium Estoniae

    Lumiste, Vello

    2008-01-01

    Rets. rmt.: Die Arithmetik-Vorlesung des Georg Joachim Rheticus Wittenberg 1536 : eine kommentierte Edition der Handschrift X-278 (8) der Estnischen Akademischen Bibliothek / herausgegeben von Stefan Deschauer. Augsburg, 2003. Lisa: Valitud osi käsikirjast

  9. Civis Europeus Sum oder: Chamberlain spielen / Robert von Lucius

    Index Scriptorium Estoniae

    Lucius, Robert von

    2014-01-01

    Baltimaade presidentidele Kuldse Victoria auhinna omistamisest. Eesti ja Leedu presidentide kõnedest. Toomas Hendrik Ilvese vestlusest Joachim Gauck'iga ja mõtteavaldustest Saksa Välissuhete Nõukogus

  10. Altar - jumala laud ja esindusobjekt / Reet Rast

    Index Scriptorium Estoniae

    Rast, Reet

    2005-01-01

    Altar kui kunstiline ülesanne. Altari teoloogiline sõnum. Püha õhtusöömaaeg - Kihelkonna kiriku altar (1591), Harju-Madise triptühhon (1631). Kristuse ristilöömine - Kärla kiriku altar (1591). Skulptuuriprogrammid, voorused. Keila kiriku altar (Tobias Heintze töökoda, 1632). Haapsalu Jaani kiriku altar (Joachim Winter, 1630). Ridala kiriku altar (Elert Thiele?, Berent Lorentz, 1678). Tallinna toomkiriku altar (Christian Ackermann, 1696, maalid: Ernst Wilhelm Londicer). Rootsi Mihkli kiriku altar (Joachim Armbrust, 1697). Juuru kiriku altar (Johann Siimsen, skulptuurid Quirinus Rabe, 1736). Bilbiograafia lk. 456-457

  11. Elurõõmust loodud Ohtu mõis / Jana Rand

    Index Scriptorium Estoniae

    Rand, Jana, 1963-

    2004-01-01

    Ohtu mõisahäärber on tagasi saanud kauni välisilme. Hoonele pandi uus kivikatus, uued aknad-uksed, krohviti seinad, taastati sepised. Mõisa ajaloost, omanikest. Lossi lasi ehitada 1760.-1770. aastail mõisnik Christoph Heinrich von Kursell. Lossi arhitektuurist, kahhelahjudest, raidkivist kaminast (Joachim Winter, 1654). Välisukse ennistas Rein Tedrekull. 10 ill

  12. pubmed.mineR: An R package with text-mining algorithms to ...

    Indian Academy of Sciences (India)

    2015-09-29

    Sep 29, 2015 ... Radlinski F and Joachims T 2007 Active exploration for learning rankings from click-through data; in Proceedings of the 13th. ACM SIGKDD International Conference on Knowledge Discov- ery and Data Mining pp 570–579. Saito R, Smoot ME, Ono K, Ruscheinski J, Wang PL, Lotia S, Pico. AR, Bader GD ...

  13. Étude histocytochimique des cals de Cicer arietinum L. confrontés ...

    African Journals Online (AJOL)

    clic

    14] Kavousi H.R., Marashi H., Mazafari J. &. Bagheri A.R., 2009. Expression of phenylpropanoid pathway genes in chickpea defense against Race 3 of. Ascochyta rabiei. Plant Pathology Journal, Vol. 8(3), 127-132. [15] Ingram D.S. & Joachim L., ...

  14. Grote botsingen: Wetenschap versus Godsdienst: Grote Conflicten van Copernicus tot Dawkins. College 1. De Copernicaanse Revolutie

    NARCIS (Netherlands)

    Philipse, H.

    2007-01-01

    Blok I. De wetenschapshistorische achtergrond a. Georg Joachim Rheticus (1514-1574) en Nicholas Copernicus (1473-1543) in Frauenburg (Frombork, in Varmia, Polen) van mei 1539 tot september 1541. Rheticus’ Narratio Prima de libris revolutionum... Nicolai Copernici (1540) en Copernicus’ Commentariolus

  15. Elamise kunst ja unistuste julgus juubeli-PÖFFil / Margit Tõnson

    Index Scriptorium Estoniae

    Tõnson, Margit, 1978-

    2006-01-01

    10nda Pimedate Ööde Filmifestivali võidufilmid : "TumeSininePeaaeguMust", režissöör Daniel Sanchez Arevalo : Hispaania 2006, "Taksitermia", režissöör György Palfi : Ungari-Austria-Prantsusmaa 2006. Lisaks Joachim Lafosse'i filmist "Eravaldus" ja Aku Louhimiehe filmist "Lahtikistud mees"

  16. Books | Page 19 | IDRC - International Development Research Centre

    International Development Research Centre (IDRC) Digital Library (Canada)

    Migratory Fishes of South America: Biology, Fisheries, and Conservation Status. Fish species that migrate within the great rivers of South America support important local fisheries but are little known outside their native range. Editor(s): Joachim Carolsfield, Brian Harvey, Carmen Ross, and Anton Baer. Publisher(s): World ...

  17. Reclamation of sodic soils in northern Tanzania, using locally ...

    African Journals Online (AJOL)

    SERVER

    2007-08-20

    Aug 20, 2007 ... locally available organic and inorganic resources. Joachim H. J. R. Makoi and Patrick A. Ndakidemi* ... food production in Tanzania and particularly in the lowlands of Kilimanjaro region remain fixed and are ..... Principles and procedures of statistics: A biometrical approach, Second Edition. McGraw Hill ...

  18. La gestion intégrée des pêches accroît la sécurité alimentaire en ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    17 sept. 2013 ... Carlos Jorge Carafa Rada, Agua Sustentable, Bolivie. Paul van Damme, Asociación FaunAgua, Bolivie. Joachim Carolsfeld, World Fisheries Trust, Canada. Partenaires. Canada : World Fisheries Trust. Bolivie : Agua Sustentable, Asociación FaunAgua. Pays : Bolivie Financement accordé : 2,5 millions ...

  19. Pages of the phytomorphology history in the monuments of material culture

    Directory of Open Access Journals (Sweden)

    Viktor Yu. Barshteyn

    2012-03-01

    Full Text Available It was reviewed Ancient Greece and Ancient Rome sources of plants morphology, plant morphology knowledge in Renaissance age – scientific works of Andrea Cesalpino, Joachim Jungius, Marcello Malpighi and plant morphology formation as the separate branch of science due to Johann Wolfgang von Goethe scientific works and its reflection in the monuments of material culture.

  20. Gender Differences in Communication Patterns of Females in Single ...

    African Journals Online (AJOL)

    Nekky Umera

    103. Gender Differences in Communication Patterns of. Females in Single-Sex and Mixed-Sex Schools in Nnewi. Education Zone. Nwosu, Eucharia Nchedo & Joachim C. Omeje ... and to assess how it differs from the same sex communication; and to ... Gender differences in communication are often the source of much.

  1. The Practice of Transnational Law

    CERN Document Server

    2000-01-01

    Contents :"The new law merchant and the global market place" by Klaus Peter Berger, "The CENTRAL enquiry on the use of transnational law in international contract law and arbitration", "The UNIDROIT principles and transnational law" by Michael Joachim Bonell, "Examples for the practical application of transnational law", "The questionnaire and results of the CENTRAL enquiry"

  2. African Health Sciences - Vol 1, No 2 (2001)

    African Journals Online (AJOL)

    Rapid detection of Mycobacterium avium subsp. paratuberculosis from cattle and zoo animals by Nested PCR · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Joseph Erume, Joachim Spergser, Renate Rosengarten, 83-89 ...

  3. C-17A Sustainment Performance Metrics Assessment: Repair Source Impact on Sustainment for Future Business Case Analysis Development

    Science.gov (United States)

    2013-06-01

    the justification of the study and segue into the creation of alternate sustainment performance metrics to incorporate into future business cases...National Academies Press\\ Hofbauer, Joachim, Sanders, Greg. Defense Industrial Initiatives Current Issues: Cost Plus Contracts. Center for Strategic...Steve, Cameron, Ian. Preliminary Industrial Assessment: An Approach for Developing Depot Sustainment Solutions. Defense AT&L. November – December

  4. Tartu Waldorf-keskus : arhitektuurne ideekonkurss / Mikk Pärdi

    Index Scriptorium Estoniae

    Pärdi, Mikk

    2013-01-01

    Arhitektuurivõistluse eesmärgiks oli leida terviklik lahendus Tartu Waldorf-keskusele: lasteaed, 12-klassiline kool ja sotsiaalkeskus. Rudolf Steinerist ja lühidalt Waldorf-pedagoogikast. Waldorf-koolide arhitektuurist. Võistlustöödest, I preemia pälvinud tööst "Birch" (Joachim Zimmer, Imme Denker, Saksamaa)

  5. Europe adrift: Illusions and Realities of the European Energy Policy

    International Nuclear Information System (INIS)

    Bitterlich, Joachim

    2013-01-01

    The European Council on 22 May will mainly be devoted to the energy question. On this occasion the Robert Schuman Foundation will be publishing a text by Joachim Bitterlich taken from the 'Schuman Report on Europe, State of the Union 2013' published in April last by Springer Verlag Editor. (author)

  6. Author Details

    African Journals Online (AJOL)

    Gbénou, Joachim. Vol 106 (2016) - Articles Étude ethnobotanique et phytochimique de Momordica charantia Linn (Cucurbitaceae) à Cotonou au Bénin Abstract PDF · Vol 109 (2017) - Articles Étude ethnobotanique, phytochimique et écotoxicologique de Ocimum gratissimum Linn (Lamiaceae) à Cotonou Abstract PDF.

  7. Statistical Analysis of High Resolution SAR Ground Clutter Data

    Science.gov (United States)

    2005-11-01

    forest zones. 166 Acknowledgments Thanks to Prof. Joachim Ender from FGAN for providing the AER-II data set, to Dr. Alberto Moreira from DLR...for providing the E-SAR data set, to Dr. Joao Moreira for providing the Aes-1 data set when at Aerosensing Radarsysteme, and to Dr. David Imel for

  8. Kant’s Doctrine of Right. A Commentary

    Directory of Open Access Journals (Sweden)

    Thomas Mertens

    2013-12-01

    Full Text Available http://dx.doi.org/10.5007/1677-2954.2013v12n2p355 Review of: B. Sharon Byrd and Joachim Hruschka, Kant’s Doctrine of Right. A Commentary (Cambridge University Press, Cambridge 2010 336 p.

  9. Migratory Fishes of South America : Biology, Fisheries, and ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Migratory Fishes of South America : Biology, Fisheries, and Conservation Status. Couverture du livre Migratory Fishes of South America : Biology, Fisheries, and Conservation Status. Directeur(s) : Joachim Carolsfield, Brian Harvey, Carmen Ross et Anton Baer. Maison(s) d'édition : World Fisheries Trust, Banque mondiale, ...

  10. Was Hendrick ter Brugghen a melancholic?

    NARCIS (Netherlands)

    Bok, M.J.

    2009-01-01

    Very few contemporary authors have written about the Utrecht painter Hendrick ter Brugghen. This makes the few words devoted to him by Joachim von Sandrart particularly precious to scholarship, especially because Sandrart characterized him as a man with "profound but melancholic thoughts"

  11. Some South African connections among students at the Hochschule ...

    African Journals Online (AJOL)

    Between 1919 and 1933, five South African born students enrolled at the Hochschule: Constance Hoesch (singing), Margarete Schoen (piano), Lucia de Kock (cello), Reinhard Behr (singing), and Joachim Speiser (piano and composition). Three students later came to South Africa: the Jewish German Heinz Hirschland ...

  12. Rootsi-Mihkli kirikus on jälle jõulud / Tiina Kanarbik

    Index Scriptorium Estoniae

    Kanarbik, Tiina

    2003-01-01

    1992. a. tagastatud Rootsi-Mihkli kogudus maja sai 2002. a. kevadeks uue katuse ja välisviimistluse, kirikusaal ning osa koguduseruume olid restaureeritud ja renoveeritud. Kiriku varadest. Altari valmistas 1703. a. puunikerdaja Joachim Armbrust, kantsli 1707. a. Christian Ackermann. Pimedate kaitsepühakust Luciast. Kommentaarid kirikuõpetaja Patrik Göranssonilt

  13. [Jean-Daniel Strub. Der gerechte Friede. Spannungsfelder eines friedensethnischen Leibegriffs.] / Andreas Pawlas

    Index Scriptorium Estoniae

    Pawlas, Andreas

    2012-01-01

    Arvustus: Strub, Jean-Daniel. Der gerechte Friede. Spannungsfelder eines friedensethnischen Leibegriffs. (Forum Systematik. beiträge zur Dogmatik, Ethik und ökumenischen Theologie, hg von Johannes Brosseder, Johannes Fischer und Joachim Track, Band 36), Verlag W. Kohlhammer, Stuttgart 2010

  14. Hetero-interaction between Gouy-Stern double layers : charge and potential regulation

    NARCIS (Netherlands)

    Lyklema, J.; Duval, J.F.L.

    2005-01-01

    This issue of Advances is devoted to the memory of Hans-Joachim Schulze who, before his untimely death, made substantial contributions in the domains of flotation, wetting and particle interaction, often under adverse working conditions. Many of his publications involve hetero-interaction between

  15. Photographing without shooting: the survival of artistic appropriation in the digital age

    Directory of Open Access Journals (Sweden)

    Susana S. Martins

    2016-06-01

    Full Text Available This article investigates the ways in which postmodern artistic appropriation resisted the digital revolution and its impact on the (immateriality of photographic objects. Drawing on the analysis of the particular production and reception processes in the work of the artist Joachim Schmid, this text investigates how art has adapted itself to the new technological landscapes in a paradoxical world, where people are shooting more than ever, while traditional photographic objects are on the verge of disappearance.

  16. Kumb oli agressor Hitler või Stalin / Rudolf Augstein

    Index Scriptorium Estoniae

    Augstein, Rudolf

    1996-01-01

    Järg Apr/13.,15.16.,17.,18.,19,20.,22.,23.,24.,25.,26. lk. 35,23,23,23,23,23,33,23,23,23,23,23. Kolme raamatu põhjal tehtud ülevaade sõjast: Vladimir Rezun "M-päev", Joachim Hoffmann "Stalini hävitussõda 1941-1945", Walter Post ""Barbarossa" plaan". Saksa ja Nõukogude kallaetungikavad 1940/41

  17. Pöff : Võistlevad Euroopa ja Aasia / Andris Feldmanis

    Index Scriptorium Estoniae

    Feldmanis, Andris, 1982-

    2006-01-01

    10nda Pimedate Ööde Filmifestivali filmidest lõpetamise eel : "TumeSininePeaaeguMust", režissöör Daniel Sanchez Arevalo : Hispaania 2006, "Taksitermia", režissöör György Palfi : Ungari-Austria-Prantsusmaa 2006, Joachim Lafosse'i filmist "Eravaldus" ja Aku Louhimiehe filmist "Lahtikistud mees". Lisatud "Mehed metsas" Eesti "Meeletu" ja Leedu "Sina olen mina"

  18. Dynamical Systems and Motion Vision.

    Science.gov (United States)

    1988-04-01

    TASK Artificial Inteligence Laboratory AREA I WORK UNIT NUMBERS 545 Technology Square . Cambridge, MA 02139 C\\ II. CONTROLLING OFFICE NAME ANO0 ADDRESS...INSTITUTE OF TECHNOLOGY ARTIFICIAL INTELLIGENCE LABORATORY A.I.Memo No. 1037 April, 1988 Dynamical Systems and Motion Vision Joachim Heel Abstract: In this... Artificial Intelligence L3 Laboratory of the Massachusetts Institute of Technology. Support for the Laboratory’s [1 Artificial Intelligence Research is

  19. The 2017 Nobel Prize in Chemistry: cryo-EM comes of age.

    Science.gov (United States)

    Shen, Peter S

    2018-03-01

    The 2017 Nobel Prize in Chemistry was awarded to Jacques Dubochet, Joachim Frank, and Richard Henderson for "developing cryo-electron microscopy (cryo-EM) for the high-resolution structure determination of biomolecules in solution." This feature article summarizes some of the major achievements leading to the development of cryo-EM and recent technological breakthroughs that have transformed the method into a mainstream tool for structure determination.

  20. [Pastoral psychology--Freud's forgotten child? The reception of psychoanalysis in pastoral care and counseling].

    Science.gov (United States)

    Noth, Isabelle

    2010-01-01

    Psychoanalysis played a decisive role in the conception and early development of pastoral psychology and continues to exercise a formative influence on this practical theological discipline. This makes it all the more astonishing that psychoanalysis takes no notice of pastoral psychology. The author broadly sketches significant stages of the reception of psychoanalysis in pastoral care and counseling, highlighting in particular the historical importance of Oskar Pfister and, half a century later, Joachim Scharfenberg.

  1. Komunikasi Pendek Koleksine Matoda Dari Sulawesi

    OpenAIRE

    Purwaningsih, E; Hartini, S; Saim, A

    2000-01-01

    Sulawesi merupakan lokasi yang menarik untuk penelitian karena jenis-jenis faunanya merupakan peralihan antara fauna Australia dan Asia (Joachim I & Williams WD. 1974. Introduction to Zoogeography.The Macmillan. 110 pp.).Di daerah ini ada beberapa kawasan Taman Nasional yang kaya akan keanekaragaman floradan fauna (Anonim. 1996. Keanekaragaman hayati di Indonesia.Kantor Menteri Negara Lingkungan Hidup dan Konsorsium Nasional untuk Pelestarian Hutan dan Alam Indonesia, Jakarta).

  2. Vappepitaafid / Jüri Kuuskemaa

    Index Scriptorium Estoniae

    Kuuskemaa, Jüri, 1942-

    2005-01-01

    Vanim Eestis säilinud vappepitaaf pärineb aastast 1640. Säilinud vappepitaafide üldarv on alla 200. Christian Ackermanni ja tema töökoja loodud vappepitaafid. 17. ja 18. sajandi vahetuse ning 18. sajandi vappepitaafid (Joachim Armbrust, Johann Valentin Rabe, Anthony Rabe). Kuni 1774. a. oli vappepitaaf funktsioneerinud hauamonumendi tähenduses, sealtpeale võis ta täita üksnes kenotaafi ülesandeid. Bibliograafia lk. 460

  3. Optical probes in biology

    CERN Document Server

    Zhang, Jin; Schultz, Carsten

    2015-01-01

    Introduction and BasicsEngineering of Optimized Fluorescent Proteins: An Overview from a Cyan and FRET Perspective Lindsay Haarbosch, Joachim Goedhart, Mark A. Hink, Laura van Weeren, Daphne S. Bindels, and Theodorus W.J. GadellaFluorescent Imaging Techniques: FRET and Complementary Methods Stefan Terjung and Yury BelyaevTracking: Sensors for Tracking BiomoleculesProtein-Based Calcium Sensors Thomas Thestrup and Oliver GriesbeckMonitoring Membrane Lipids with Protein Domains Expressed in Living Cells Peter Varnai

  4. The Inner Cold War: State Party Control and East German Society

    Science.gov (United States)

    2014-06-01

    with a very different ideology and in principle far more humanistic set of goals, yet with a comparable disregard for individual human rights and...trained psychologist Joachim Maaz writes, “the goal of state education can 111 Fulbrook, The People’s...the universities were far too focused upon humanistic research for the Party’s taste,”185 and prompted reforms in these areas starting in 1951. The

  5. Efficacy and safety of an oral contraceptive containing ethinylestradiol 20 µg/drospirenone 3 mg (24/4 regimen) in three indications in the People's Republic of China: a comparison with international studies

    OpenAIRE

    Marr J; Huang Z; Wang B; Zhang H; Roth K

    2015-01-01

    Joachim Marr,1 Zirong Huang,2 Baoxi Wang,3 Hongyan Zhang,4 Katrin Roth1 1Bayer Pharma AG, Berlin, Germany; 2Obstetrics and Gynecology Hospital of Fudan University, Shanghai, 3Institute of Dermatology, Chinese Academy of Medical Sciences, Nanjing, Jiangsu, 4Peking University Sixth Hospital, Peking University Institute of Mental Health, Ministry of Health (Peking University), Beijing, People's Republic of China Abstract: While combined oral contraceptives are a popular...

  6. The Influence of Detoxification on the Quality of Life in Substance Addicts Lives With 40-65 Years of Age Referring to the Charity “Ongress60

    Directory of Open Access Journals (Sweden)

    Mahmood Tavakoli

    2012-03-01

    Full Text Available Objectives: during the last two decades , Activities concerning demand reduction and specially addict’s treatment and rehab have outstandingly improved in Iran. Now different treatment alternatives such as outpatient and residential care centers such as‚ abstinence based and spiritual therapies like, narcotic anonymous are developed. Treatment program in human recovery population is replacing opium tincture and gradually reduction of it (during 11 month. And it includes group and spiritual therapies. Methods & Materials: this research is a descriptive study which has been done cohort and longitudinal during 3 months (from the beginning’ one and three months after entrance. In this research, the quality of life has been assessed. Participants include all addicts over 40 who have referred to the society (congress 60 for detoxification. Choosing the samples has been based on the method of accessible sampling. Demographic questionnaire and life quality questionnaire have been collecting information tools. Data’s have been analyzed by software spss. Results: out of 33 people, 15 were over 50 years old. The substance abused include: Opium abuse With the frequency of 12 people (36.4% ‚heroin crack with the frequency of 14 people (42.2% had the most frequency. Monthly cost of drug abusing is on average 159/849 toomans, for each person. for all subscales of life quality, P-value has been reported below 0.05. Conclusion: Detoxification has been effective in improving quality of life. just for the two following questions the persons opinion has not changed during three periods: "it seems that I get diseases easier than others" and my health is the same as other people I know". it can be said perhaps short period treatments have little influence on the change of "ones deep attitude towards himself" and a deep, essential change of attitude needs long period rehabilitation programs.

  7. Recent advances in remote sensing and geoinformation processing for land degradation assessment

    CERN Document Server

    Roeder, Achim

    2009-01-01

    Acknowledgements Contributors Achim Röder & Joachim Hill, Remote sensing and geoinformation processing in land degradation assessment-an introduction Part 1 Setting the scene: principles in remote sensing and spatial scene modelling for land degradation assessmentEric F. Lambin, Helmut Geist, James F. Reynolds & D. Mark Stafford-Smith, Coupled human-environment system approaches to desertification: Linking people to pixels Susan L. Ustin, Alacia Palacios-Orueta, Michael L. Whiting, Stéphane Jacquemoud & Lin Li, Remote sensing based assessm

  8. Robert Boyle, Transmutation, and the History of Chemistry before Lavoisier: A Response to Kuhn.

    Science.gov (United States)

    Newman, William R

    2014-01-01

    In an influential article of 1952, Thomas Kuhn argued that Robert Boyle had little or no influence on the subsequent development of chemistry. This essay challenges Kuhn's view on two fronts. First, it shows that Johann Joachim Becher developed his hierarchical matter theory under the influence of Boyle and then transmitted it to the founder of the phlogiston theory, G. E. Stahl. Second, this essay argues that transmutational matter theories were not necessarily opposed to the existence of stable chemical species, pace Kuhn. Boyle's corpuscular theory descended largely from the tradition of "chymical atomism," which often advocated both chrysopoeia and the reality of robust chemical substances.

  9. Lamentationes Jeremiae Prophetae de Orlando Di Lasso: algumas figuras retórico-musicais na Lamentatio Prima Primi Diei (Feria Quinta In Coena Domini)

    OpenAIRE

    Ambiel,Áurea Helena de Jesus

    2008-01-01

    Este artigo tem como proposta a identificação, na primeira lição das Lamentationes Jeremiae Prophetae, de Orlando Di Lasso (Lamentatio Prima Primi Diei), de figuras retórico-musicais, utilizando a terminologia de época. Para tanto, o trabalho está baseado principalmente na obra Musica Poetica (Rostock, 1606) de Joachim Burmeister, tradução de Benito V. Rivera (Musical Poetics, 1993). A pesquisa faz parte de um projeto de doutorado, que tem como objeto de estudo a obra completa Lamentationes J...

  10. Acquisitions de la Bibliothèque de l’Institut de Géographie

    Directory of Open Access Journals (Sweden)

    2009-10-01

    Full Text Available AfriqueAMBOULOU, Zéphirin Sédar, La marche difficile du Congo vers un développement socioéconomique harmonieux et durable, Paris, Publibook, [2009], G 19-3478 AVENOT, Aimé Félix, La décentralisation territoriale au Gabon : entre mimétisme et mystification, Paris, L’Harmattan, DL 2008, G 19-3464 BÂ, Boubacar, Agriculture et sécurité alimentaire au Sénégal, Paris, L’Harmattan, DL 2008, G 19-3463 BANGASSARO COULIBALY, Nguessé Joachim, Le  mal ivoirien : cas symptomatique du mal africain, Paris, ...

  11. Tallinna Raekoda. Aeg ja lugu = Tallinn Town Hall - Its Story Through Time / Elvira Liiver Holmström

    Index Scriptorium Estoniae

    Liiver Holmström, Elvira

    2004-01-01

    Raekoja kujunemislugu. Esindussaalid, ameti- ja tarberuumid. Raekoda 17.-20. sajandil. Hoone ümberehitamist 1402-1404 juhtis kiviraidur Ghercke. Hinrik Hartmanni poolt valatud kell paigutati torni 1586. a. 17. sajandil tegi hilisrenessanss-stiilis torni joonised Geiger Graff, lääneviilule uue harjakivi ja tuulelippu hoidva lõvi Hans Damm, lohepeakujulised veesülitid ja tuulelipu lipu Daniel Pöppel, raesaali paigutati Johann Akeni lünettmaalid, nende all paikneva puitnikerdfriisi valmistasid Elert Thiele ja Joachim Armbrust. 1859. a. ümberehitusprojekti koostas Christoph August Gabler

  12. Investigating the Interdependencies of the Energy Balance Closure and the Turbulent Kinetic Energy Budget.

    Science.gov (United States)

    Banerjee, T.; Zeeman, M. J.; De Roo, F.; Brugger, P.; Mauder, M.

    2016-12-01

    The energy balance residual (EBR), defined as the difference between the available energy (sum of net radiation and ground heat flux) and the turbulent fluxes of latent and sensible heat, is often found to have a large positive value. Several land surface experiments and flux networks report an average energy balance closure of approximately 80%. Although different factors can influence the energy balance closure across measurement campaigns, a significant EBR even when sites are horizontally with short canopies indicates of a systematic bias resulting from the general underestimation of the aerodynamic transport of energy, especially horizontal divergence of the mean advective fluxes and transport by low-frequency motions generally called `secondary circulations'. These low frequency local transports can occur from various processes such as coherent large scale organized motions, convective cells and even significant transient changes. Thus, we decided to study the budget of the turbulent kinetic energy (TKE) in conjunction with the energy balance closure. In the current work, this interdependency has been investigated using surface flux (Eddy Covariance) and remote sensing based measurements (triple 3d Doppler LiDAR, thermal imagery) from the ScaleX campaigns at the TERENO pre-alpine observatory Fendt in Southern Germany (with gentle topography), coupled with large eddy simulations (LES). Statistical methods ranging from dimensional reduction techniques to information theory has been used to extract the effects and significance of aforementioned processes towards explaining the observed annual average EBR of about 50 Wm-2. Initial results indicate a high correlation between EBR and the TKE dissipation rate, as well as the skewness of vertical velocity, confirming the role of secondary circulations. The role of transport and the advection terms will also be investigated. Overall, improved understanding of such connections between the fundamental mechanisms of TKE

  13. Multi-Scale Observation and Modelling of Energy and Matter Exchange in the Atmospheric Boundary-Layer (ScaleX Campaigns)

    Science.gov (United States)

    Zeeman, M. J.; Wolz, K.; Adler, B.; Brenner, C.; De Roo, F.; Emeis, S.; Kalthoff, N.; Mauder, M.; Schäfer, K.; Wohlfahrt, G.; Zhao, P.

    2016-12-01

    We investigated biosphere-atmosphere exchange processes in relation to the atmospheric boundary-layer (ABL) flow in a shallow valley. Land-use heterogeneity and topography can force local atmospheric flow patterns, including local circulations. Such flow patterns can impair current techniques for the quantification and source attribution of surface-exchange fluxes due to flux-divergence, advection and decoupling. Wind field, temperature and humidity structures in the ABL were observed in high resolution with spatially distributed observations in a 1 km3 experimental domain. Remote-sensing observations of wind, temperature and particles in the ABL (Raman-lidar; RASS; ceilometer; microwave radiometer; 3D Doppler-lidar) were combined with a high-resolution network of in-situ observations that included vertical and horizontal profiles of wind, temperature, carbon dioxide, methane and water vapor concentrations. The experiments were co-located with the long-term eddy covariance (EC) observatory Fendt (DE-Fen; ICOS, TERENO) and were part of international cooperative efforts in 2015 and 2016 (the ScaleX campaigns). The gathered experimental data offers a scale-transcending insight in local flow patterns in mountainous terrain and their influence on surface-exchange fluxes of energy and matter as observed by EC and flux-gradient methodology. In addition, the data is used for validation of Large-Eddy Simulations in complex terrain using PALM-LES. Within this modelling framework, virtual measurements are conducted to further assess the importance of three-dimensional advective and horizontal turbulent transport terms.

  14. Le musée français: guerras napoleônicas, coleções artísticas e o longínquo destino de um livro

    Directory of Open Access Journals (Sweden)

    Guilherme Sim\\u00F5es Gomes J\\u00FAnior

    2007-01-01

    Full Text Available This paper is about Le Musée Français [The French Museum], a book found in the collection of the library of the Imperial Academy of Fine Arts in Rio de Janeiro. As a catalog of the Napoleon Museum, it bears witness to the reorganization of the arts in Europe as a result of the Napoleonic wars and the project of making Paris a true successor to Athens and Rome, as the center of a new republic of the arts. This process was the object of a dispute where Quatremère de Quincy and Joachim Lebreton played an important role. It was also one of the causes leading to the exile of a group of artists who then helped to lay the foundations for an academic environment in Rio de Janeiro.

  15. Verivärskeid elamusi igale maitsele / Marianne Kõrver

    Index Scriptorium Estoniae

    Kõrver, Marianne, 1980-

    2007-01-01

    Ülevaade 10. PÖFFi võistlusprogrammist. PÖFFi filme: "Meeletu" (rezh. Elmo Nüganen), "TumeSininePeaaeguMust" (rezh. Daniel Sanchez Arevalo), "Taksitermia" (rezh. György Palfi), "Eravaldus" (rezh. Joachim Lafosse), "Lahtikistud mees" (rezh. Aku Louhimies), "Rõhkkonnad" (rezh. Nuri Bilge Ceylan), "Reekviem" (rezh. Hans-Christian Schmid), "Väikesed punased lilled" (rezh. Zhang Yuan), "Sündroomid ja sajand" (režissöör Apichatpong Weerasethakul), "Mängides ohvrit" (rezh. Kirill Serebrennikov), "Et taevasse pääseda, tuleb kõigepealt surra" (rezh. Djamshed Usmonov), "Pojad" (rezh. Erik Strand Richter), "Maximo Oliverose õitseaeg" (rezh. Auraeus Solito), "Kelner" (rezh. Alex van Warmerdam), "Tagasinõudja" (rezh. Slawomir Fabick), "Mehed tööl" (rezh. Mani Haghighi), "4,6 miljardit aastat armastust" (rezh. Takashi Miike), "Sina oled mina" (rezh. Kristijonas Vildziunas)

  16. Arendt-Fest: "autori di grandi crimini politici" o "grandi criminali politici"?

    Directory of Open Access Journals (Sweden)

    Valentina

    2015-09-01

    Full Text Available The drive to understand the reasons that led to the Holocaust clearly emerges in some of Hannah Arendt works, such as The Image of Hell (1946, The Origins of Totalitarianism (1951, 19582, 19663, Understanding and Politics (1954, where the author reasons on the concept of «banality of evil». In order to understand her angle on the issue of evil one should also consider the 1964 radio interview between the philosopher and Joachim Fest. This interview provides remarkable insight as it goes deep into the meaning of evil – which it defines «banal» – and touches upon several moral, philosophical and legal arguments connected to it. Moreover, it sheds light on the act/empty function, sense of responsibility/lack of remorse, consensus/obedience, spontaneity/calculation antitheses that explain Arendt’s irreducible opposition between politics and totalitarianism.

  17. ‘Winckelmann in Poland: An Eighteenth-Century Response to the “History of the Art of Antiquity”’

    Directory of Open Access Journals (Sweden)

    Carolyn C. Guile

    2013-12-01

    Full Text Available The art historical writings of Stanislaw Kostka Potocki (1755-1821 are little-known outside of Poland. Potocki intended, On the Art of the Ancients, or the Polish Winckelmann (O Sztuce u Dawnych, czyli Winkelman Polski, 1815 to be a history of world art that used Johann Joachim Winckelmann’s system of analysis as its point of reference. The importance for art historiography of Potocki’s project resides in the presentation of Winckelmann’s Geschichte der Kunst des Altertums (1764 for a Polish readership, in his consideration of cultures Winckelmann had not discussed and in his defense of Winckelmann’s approach against Christian Gottlob Heyne’s critique. Written when art history was a discipline in formation, Potocki’s text gave Winckelmann’s project an ‘afterlife’ in the eastern borderlands of Europe.

  18. Executive committee

    Science.gov (United States)

    Xiao, Guoqing; Cai, Xiaohong; Ding, Dajun; Ma, Xinwen; Zhao, Yongtao

    2014-04-01

    ChairVice Chair Toshiyuki AzumaRoberto Rivarola Atomic, Molecular & Optical Physics LabUniversidad Nacional de Rosario and Advanced Science InstituteInstituto de Fisica Rosario RIKEN, JapanRosario, Argentina SecretaryMembers Dominique VernhetJoachim Burgdörfer, Austria Institut des NanoSciences de Paris Birgit Lohmann, Australia Université Pierre et Marie Curie Hossein Sadeghpour, USA Paris, FranceThomas Stöhlker, Germany Past ChairJim McCann, UK Barry DunningGuoqing Xiao, China Physics & AstronomyXiaohong Cai, China Rice University, HoustonXinwen Ma, China Texas, USAYongtao Zhao, China TreasurerFernando Martin, Spain Henrik CederquistLuis Mendez, Spain Alba Nova University CenterAnatoli Kheifets, Australia Stockholm University Stockholm, Sweden Details of the general committee are available in the PDF

  19. Concepts for the Formation of Molecular Nanostructures: Self-Assembly and SPM Manipulation -- A Combined Approach.

    Science.gov (United States)

    Jung, Thomas A.

    1996-03-01

    We(Work performed in collaboration with J.K. Gimzewski and R. R. Schlittler, IBM Rüschlikon, and C. Joachim and Hao Tang, CNRS Toulouse,) (Supported by the BBW of Switzerland through the ESPRIT basic research program PRONANO (8523). ) demonstrate the controlled generation of molecular nanostructures based on specific chemical synthesis and well-controlled epitaxial growth. Such structures, assembled in parallel by growth kinetics, can be modified selectively by manipulating individual molecules using different modes of the scanning tunneling microscope. The influence of molecular structure on such properties as mobility, conformational adaptation to the substrate, and the current/voltage (I/V) characteristic are compared for porphyrin molecules with different substituents. Numerical simulations are related to experimentally accessible parameters. The resulting rules and concepts are to be generalized and applied to the design of nanostructures having more specific functional properties.

  20. Une précieuse découverte : un recueil de textes aristotéliciens réunis par Sebastián Fox Morcillo et annotés de sa main (BNE R/25106

    Directory of Open Access Journals (Sweden)

    Mélanie JECKER

    2012-06-01

    Full Text Available L’extrême intérêt du livre conservé à la Bibliothèque nationale d’Espagne sous la cote R/25106 avait jusqu’à présent échappé aux érudits car son contenu exact était méconnu : le volume réunit quatre livres indépendants publiés à des dates différentes : la Politique d’Aristote traduite par Juan Ginés de Sepúlveda (1548, l’Ethique à Nicomaque traduite par Joachim Périon (1549, l’Economique traduite par Strebaeus (1551 et le commentaire sur l’Ethique de Joachim Périon (1540. Or de nombreux passages de ces quatre textes sont soulignés et annotés, et la même main a écrit sur la première page du recueil le nom d’une grande figure de l’humanisme castillan du XVIe siècle, « Sebastianus Foxius Morzillus ». Il semble donc que Sebastián Fox Morcillo a lui-même rassemblé ces quatre livres en un seul, puis les a lus et annotés en vue de rédiger ses propres traités sur les rapports entre la philosophie de Platon et celle d’Aristote. J’espère pouvoir démontrer dans un prochain article les liens entre ces traités de Fox Morcillo et les annotations du recueil conservé à la BNE.Desconociéndose el contenido exacto del libro conservado en la Biblioteca Nacional de España con la signatura R/25106, no se había percibido hasta ahora su verdadera índole y por lo tanto su gran interés. El volumen reúne cuatro libros independientes publicados en fechas distintas : la Política de Aristóteles traducida por Juan Ginés de Sepúlveda (1548, la Ética traducida por Joachim Périon (1549, la Económica traducida por Strebaeus (1551 y el comentario de la Ética por Joachim Périon (1540. Numerosos pasajes de estas cuatro obras están subrayados y anotados por la misma mano que escribió al principio del libro « Sebastianus Foxius Morzillus », es decir Sebastián Fox Morcillo, gran figura del humanismo español del siglo XVI. Se puede por consiguiente formular la hipótesis de que el propio Fox

  1. Intoduction to the Issue (2011/2

    Directory of Open Access Journals (Sweden)

    Wojciech HANUSZKIEWICZ

    2011-12-01

    Full Text Available Seven articles — out of the nine presented here to the Reader — undertake our leading theme: Tracing Liminal and Boundary Experience in Philosophical and Religious Discourse. Three articles from that group (written by Małgorzata Bogaczyk-Vormayr, Piotr Augustyniak and Anna Szyrwińskaexplore various aspects of the boundary experience in a historical perspective. The next four pick up the same theme in a contemporary perspective: the articles of Joachim Piecuch, Tadeusz Gadacz and Antoni Szwed discuss the philosophy of Józef Tischner, the article by Urszula Idziak presents the debate between Jacques Derrida and Paul Ricoeur concerning the boundary experience of death. The remaining two articles published here are not connected with the leading theme — Magdalena Nowak presents a history of the concept of Einfühlung and Jacquette Dale tries to improve the diagram method used in logical argument analysis.

  2. Implications of the thyroid hormone on neuronal development with special emphasis on the calmodulin-kinase IV pathway.

    Science.gov (United States)

    Krebs, Joachim

    2017-06-01

    Thyroid hormones influence brain development through regulation of gene expression. This is especially true for Ca 2+ -dependent regulation since a major pathway is controlled by the Ca 2+ /calmodulin-dependent protein kinase IV (CaMKIV) which in turn is induced by the thyroid hormone T 3 . In addition, CaMKIV is involved in regulation of alternative splicing of a number of protein isoforms, among them PMCA1a, the neuronal specific isoform of the plasma membrane calcium pump. On the other hand, hypothyroidism or CaMKIV deficiency can have a severe influence on brain development. This article is part of a Special Issue entitled: ECS Meeting edited by Claus Heizmann, Joachim Krebs and Jacques Haiech. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. Computational methods for three-dimensional microscopy reconstruction

    CERN Document Server

    Frank, Joachim

    2014-01-01

    Approaches to the recovery of three-dimensional information on a biological object, which are often formulated or implemented initially in an intuitive way, are concisely described here based on physical models of the object and the image-formation process. Both three-dimensional electron microscopy and X-ray tomography can be captured in the same mathematical framework, leading to closely-related computational approaches, but the methodologies differ in detail and hence pose different challenges. The editors of this volume, Gabor T. Herman and Joachim Frank, are experts in the respective methodologies and present research at the forefront of biological imaging and structural biology.   Computational Methods for Three-Dimensional Microscopy Reconstruction will serve as a useful resource for scholars interested in the development of computational methods for structural biology and cell biology, particularly in the area of 3D imaging and modeling.

  4. Badania nad historią filozofii przyrody i historią nauki

    Directory of Open Access Journals (Sweden)

    Janusz Mączka

    2012-06-01

    Full Text Available This is a review of research conducted by the Center for Interdisciplinary Studies and the Copernicus Center for Interdisciplinary Studies in the field of the history of philosophy of nature and the history of philosophy of science in Poland in the inter-war period. In spite of the domination of positivistic philosophy that tended to ignore philosophy of nature, this kind of philosophizing was quite popular in Poland. The review begins with a summary of works related to the history of science, and then deals, in some detail, with works on the theory of evolution and the theory of relativity, especially with their philosophical aspects. The remaining part of the review is devoted to the principal personalities of that period, namely: Władysław Heinrich, Władysław Natanson, Tadeusz Grabowski, Marian Smoluchowski, Zygmunt Zawirski and Joachim Metallmann.

  5. Historical sources about diseases, death and embalming regarding the family of Jean Antoine Michel Agar, Minister of Finance of Gioacchino Murat.

    Science.gov (United States)

    Marinozzi, S; Gazzaniga, V; Giuffra, V; Fornaciari, G

    2011-06-01

    Among the mummies preserved in the Basilica of San Domenico Maggiore in Naples, there are the bodies of the wife and three children of Jean Antoine Michel Agar, Minister of Finance of Naple's Kingdom during the Monarchy of Joachim Murat (1808-1815). Between 1983 and 1987 paleopathological analyses were performed; in particular, X-ray examination allowed investigation of the health status of the Agar family members and reconstruction of the embalming processes used to preserve the bodies. In addition, an analysis of the historical and archival documents was carried out, to formulate hypotheses about the causes of death, demonstrating how these sources could become important instruments to obtain diagnoses and pathological histories.

  6. Workshop on the Magellanic Clouds and other Dwarf Galaxies

    CERN Document Server

    Richtler, T; Richtler, Tom; Braun, Jochen M.

    1998-01-01

    The Workshop 'The Magellanic Clouds and Other Dwarf Galaxies' was held at the Physikzentrum Bad Honnef in January 1998. The proceedings comprise 79 contributions. About 1/3 of the 352 pages contain the following Reviews: The Violent Interstellar Medium in Dwarf Galaxies: Atomic Gas (Elias Brinks and Fabian Walter), Hot Gas in the Large Magellanic Cloud (You-Hua Chu), Astrophysics of Dwarf Galaxies: Structures and Stellar Populations (John S. Gallagher), Star-forming regions and ionized gas in irregular galaxies (Deidre A. Hunter), The Law of Star Formation in Disk Galaxies (Joachim Koeppen), Strange Dark Matters in Nearby Dwarf Galaxies (Mario Mateo), Holes and Shells in Galaxies: Observations versus Theoretical Concepts (Jan Palous), Detailed Recent Star Formation Histories of Dwarf Irregular Galaxies and Their Many Uses (Evan D. Skillman et al.), and Nearby Young Dwarf Galaxies (Trinh X. Thuan and Yuri I. Izotov). See the complete electronic version for further details.

  7. TOTEM Construction Complete

    CERN Multimedia

    Katarina Anthony

    2011-01-01

    The winter technical stop saw the final steps of the installation of the TOTEM experiment. After 8 years of development, the inelastic telescope T1 was successfully installed inside CMS at both sides of the interaction point. This detector joins the previously installed inelastic telescope T2 and the Roman Pots (147m and 220m from the CMS interaction point) to study both elastic and inelastic proton scattering.   The Genova team who designed and built the detector in front of the '+' arm of the T1 telescope after final insertion. All the detector chambers were assembled at the Petersburg Nuclear Physics Institute, Gatchina, Russia. Major contributions to the construction of the support structure and the installation process came from CERN. “Installing the T1 detector was an important milestone for TOTEM,” says Joachim Baechler, Technical Coordinator for TOTEM. Enrico Robutti from Genova, responsible for the T1 project, added: "The T1 detector was carefully installed ...

  8. Report on the Workshop and Regular Meeting of the Imode-CKD and Bcmolmed Marie Curie Training and Research Programs.

    Science.gov (United States)

    Krochmal, Magdalena; Cisek, Katryna; Markoska, Katerina; Spasovski, Goce; Vlahou, Antonia

    2015-01-01

    A Workshop and Regular Meeting of the Marie Curie Training and Research Programs iMODECKD (Identification of the Molecular Determinants of established Chronic Kidney Disease) and BCMolMed (Molecular Medicine for Bladder Cancer) was held from 20-22 March at the Macedonian Academy of Science and Arts (MASA). The meeting was hosted by the participating center University of Skopje (SKO) - Goce Spasovski and MASA - Momir Polenakovic (R. Macedonia). The representative from MASA proteomic research center - Katerina Davalieva (R. Macedonia) had presentation on proteomic research in prostate cancer (PCa). 40 researchers from 13 different countries participated at the meeting. The Workshop was devoted on "Chronic Kidney Disease: Clinical Management issues", and consisted of 15 oral presentations given by nephrologists and experts in the field of CKD. Raymond Vanholder (Belgium) - past president of ERA-EDTA had a keynote lecture on "CKD: Questions that need to be answered and are not (or at least not entirely)". The workshop continued in four sessions with lectures from Alberto Ortiz (Spain), Olivera Stojceva-Taneva (R. Macedonia), Dimitrios Goumenos (Greece), Joachim Beige (Germany), Marian Klinger (Poland), Goce Spasovski (R. Macedonia), Joachim Jankowski (Germany), Adalbert Schiller (Romania), Robert Johnson (USA), Franco Ferrario (Italy), Ivan Rychlik (Czech Republic), Fulvio Magni (Italy) and Giovambattista Capasso (Italy), all covering a training theme. Within the meeting there were two lectures on complimentary skills for ethics in science and career advancement from two principal investigators - Goce Spasovski (R. Macedonia) and Joost Schanstra (France). During the Regular Meeting, 13 PhD students i.e. Early Stage Researchers and one Experienced Researcher from both Programs presented their work and progress within iMODE-CKD and BCMolMed projects. This meeting was a great opportunity to exchange experience and ideas in the field of systems biology approaches and

  9. Isotopic Geochemistry Applied on Mortars of the Katholikon of the Monastery of Timios Prodromos in the Prefecture of Serres, Greece

    Science.gov (United States)

    Dotsika, Elissavet; Iliadis, Efstathios; Kyropoulou, Daphne; Karalis, Petros

    2017-12-01

    The Monastery of Timios Prodromos is the most important Byzantine monument in the prefecture of Serres and one of the most important monastic foundations of Byzantine times in Northern Greece. It was founded in the late 13th century from Ioannikios and then renovated by his nephew, Joachim. The catholic dates back to the 14th century, and specifically between 1300-1333, under the rule of the second founder Joachim. Considering the pathology of Byzantine mural, for the most effective work on removal of over-paintings layer, fixing, restoration, recovery and maintenance of the painted surface and the substrate, it was decided the sampling from exact points of the mural painting representing the different phases, in order to determine their composition, the technology of construction materials, corrosion mechanisms and the proposal for restoration methodology. The methods to be used require very small quantities of material. The measurements are considered almost non-destructive and based on isotopic geochemistry. The techniques used are X-ray diffraction (XRD), scanning electron microscopy (SEM / EDXA) and isotopic analyzes (d18O and d13C) in a mass spectrometer (IRMS). The study of the samples was carried out by scanning electron microscopy with X-ray microanalyser and analysis of stable isotopes. The study shows that apart from the calcite present in all pigment samples, straw was used as a binder. There is also a mixing of dyes to produce the desired tint while in many cases there are different colour layers. The decay in the mural is extensive, especially in the lower layers of the wall, which have been severely affected by humidity and candle smoke. The creation of gypsum on the surface of the murals is intense and evident in most of the spectra taken

  10. Rojas, Chaucer et Shakespeare au miroir de l'iconographie : les trois âges de la femme

    Directory of Open Access Journals (Sweden)

    Sandra Gorgievski

    2010-06-01

    Full Text Available La mise en perspective de La Celestina de Fernando de Rojas, Troilus and Criseyde de Chaucer et Troilus and Cressida de Shakespeare met à jour des résonnances dans la parodie du triangle courtois (l’amoureux, la femme, l’entremetteur et la peinture du désenchantement du monde. Dans l’Europe médiévale et renaissante, l’image de la femme tentatrice peut aussi être mise en relation avec le thème iconographique des Trois âges de la femme et la Mort, mais aussi celui de la Tentation de saint Antoine (Hans Baldung, Jérôme Bosch, Pieter Huys, Joachim Patinir, mêlant sacré et profane, érotisme et morbidité. Au-delà des aspects tragiques, Chaucer célèbre l’amour terrestre et spirituel - dans sa célèbre rétractation, alors que la satire et le grotesque dominent chez Rojas et Shakespeare.Placing in parallel Fernando de Rojas’ La Celestina, Chaucer’s Troilus and Criseyde and Shakespeare’s Troilus and Cressida, one can find resonances in these works’ parody of the courtly triangle (the lovers, the go-between and their representation of a disenchanted world. In Medieval and Renaissance Europe, the image of the seductive woman can also be related to the iconographic themes of the Three Ages of Woman and Death and the Temptation of Saint Antonio (Hans Baldung, Hieronymus Bosch, Pieter Huys, Joachim Patinir, which mingle the sacred and the profane, the erotic and the morbid. Beyond tragic overtones, Chaucer celebrates both earthly and spiritual love in his famous retraction, while Rojas and Shakespeare highlight the grotesque and the satirical.

  11. Spatiotemporal variability of water and energy fluxes: TERENO- prealpine hydrometeorological data analysis and inverse modeling with GEOtop and PEST

    Science.gov (United States)

    Soltani, M.; Kunstmann, H.; Laux, P.; Mauder, M.

    2016-12-01

    In mountainous and prealpine regions echohydrological processes exhibit rapid changes within short distances due to the complex orography and strong elevation gradients. Water- and energy fluxes between the land surface and the atmosphere are crucial drivers for nearly all ecosystem processes. The aim of this research is to analyze the variability of surface water- and energy fluxes by both comprehensive observational hydrometeorological data analysis and process-based high resolution hydrological modeling for a mountainous and prealpine region in Germany. We particularly focus on the closure of the observed energy balance and on the added value of energy flux observations for parameter estimation in our hydrological model (GEOtop) by inverse modeling using PEST. Our study area is the catchment of the river Rott (55 km2), being part of the TERENO prealpine observatory in Southern Germany, and we focus particularly on the observations during the summer episode May to July 2013. We present the coupling of GEOtop and the parameter estimation tool PEST, which is based on the Gauss-Marquardt-Levenberg method, a gradient-based nonlinear parameter estimation algorithm. Estimation of the surface energy partitioning during the data analysis process revealed that the latent heat flux was considered as the main consumer of available energy. The relative imbalance was largest during nocturnal periods. An energy imbalance was observed at the eddy-covariance site Fendt due to either underestimated turbulent fluxes or overestimated available energy. The calculation of the simulated energy and water balances for the entire catchment indicated that 78% of net radiation leaves the catchment as latent heat flux, 17% as sensible heat, and 5% enters the soil in the form of soil heat flux. 45% of the catchment aggregated precipitation leaves the catchment as discharge and 55% as evaporation. Using the developed GEOtop-PEST interface, the hydrological model is calibrated by comparing

  12. The Dual Orexin Receptor Antagonist Almorexant Induces Sleep and Decreases Orexin-Induced Locomotion by Blocking Orexin 2 Receptors

    Science.gov (United States)

    Mang, Géraldine M.; Dürst, Thomas; Bürki, Hugo; Imobersteg, Stefan; Abramowski, Dorothee; Schuepbach, Edi; Hoyer, Daniel; Fendt, Markus; Gee, Christine E.

    2012-01-01

    Study Objectives: Orexin peptides activate orexin 1 and orexin 2 receptors (OX1R and OX2R), regulate locomotion and sleep-wake. The dual OX1R/OX2R antagonist almorexant reduces activity and promotes sleep in multiple species, including man. The relative contributions of the two receptors in locomotion and sleep/wake regulation were investigated in mice. Design: Mice lacking orexin receptors were used to determine the contribution of OX1R and OX2R to orexin A-induced locomotion and to almorexant-induced sleep. Setting: N/A. Patients or Participants: C57BL/6J mice and OX1R+/+, OX1R-/-, OX2R+/+, OX2R-/- and OX1R-/-/OX2R-/- mice. Interventions: Intracerebroventricular orexin A; oral dosing of almorexant. Measurements and Results: Almorexant attenuated orexin A-induced locomotion. As in other species, almorexant dose-dependently increased rapid eye movement sleep (REM) and nonREM sleep in mice. Almorexant and orexin A were ineffective in OX1R-/-/OX2R-/- mice. Both orexin A-induced locomotion and sleep induction by almorexant were absent in OX2R-/- mice. Interestingly, almorexant did not induce cataplexy in wild-type mice under conditions where cataplexy was seen in mice lacking orexins and in OX1R-/-/OX2R-/- mice. Almorexant dissociates very slowly from OX2R as measured functionally and in radioligand binding. Under non equilibrium conditions in vitro, almorexant was a dual antagonist whereas at equilibrium, almorexant became OX2R selective. Conclusions: In vivo, almorexant specifically inhibits the actions of orexin A. The two known orexin receptors mediate sleep induction by almorexant and orexin A-induced locomotion. However, OX2R activation mediates locomotion induction by orexin A and antagonism of OX2R is sufficient to promote sleep in mice. Citation: Mang GM; Dürst T; Bürki H; Imobersteg S; Abramowski D; Schuepbach E; Hoyer D; Fendt M; Gee CE. The dual orexin receptor antagonist almorexant induces sleep and decreases orexin-induced locomotion by blocking orexin

  13. Sobre el milenarismo de Joaquín de Fiore: Una lectura retrospectiva

    Directory of Open Access Journals (Sweden)

    Josep Ignasi Saranyana

    2003-01-01

    Full Text Available El artículo analiza la obra de Joaquín de Fiore y sostiene que hay un auténtico gap entre el Joaquín de la historia y el joaquinismo, de forma que Joaquín se ha convertido en un imaginario en el que se han proyectado muchas de las aspiraciones de la humanidad a lo largo de los siglos. Añade que en todo caso es preciso reconocer que el florense ha podido dar pie para ese proceso histórico de recreación. La hipótesis que se plantea es que se ha producido una disociación entre la verdadera doctrina del Abad florense y la recepción que de ella ha hecho un sector radicalizado de la fraternidad franciscana (los 'espirituales' o 'fraticelos'. La mitificación del profeta Joaquín ha dado lugar al joaquinismo. En definitiva, no está suficientemente fundada la opinión que adscribe al florense al premilenarismo, esto es, a la tesis que sostiene que Cristo vendrá para reinar mil años, en un transcurso histórico previo a la resurrección final de todos los muertos. Finalmente, es posible que la tesis de Joaquín sobre el tercer estado, sin signos ni figuras, haya permitido, según los términos utilizados en este artículo, una interpretación postmilenarista, esto es, la idea de un milenio de progresiva maduración de los dones evangélicos y de felicidad cada vez más perfecta e irreversible, al cabo del cual tendría lugar la parusíaThis article analyses the work by Joachim de Fiore, claiming that there is a gap between the historical Joachim and the real Joachinism, which has turned him into an imaginary figure, in whom most of the humanity's ambitions have been reflected for years. The author argues that de Fiore might have given good reasons for this historical process of recreation. The hypothesis here put forward, is that a dissociation has occurred between the true doctrine of the Abbot de Fiore and its reception form a radical sector of the Franciscan fraternity (the spirituals or 'fraticeleos'. His mithification has given rise to

  14. Effect of water on the fluorine and chlorine partitioning behavior between olivine and silicate melt

    Science.gov (United States)

    Joachim, Bastian; Stechern, André; Ludwig, Thomas; Konzett, Jürgen; Pawley, Alison; Ruzié-Hamilton, Lorraine; Clay, Patricia L.; Burgess, Ray; Ballentine, Christopher J.

    2017-04-01

    Halogens show a range from moderate (F) to highly (Cl, Br, I) volatile and incompatible behavior, which makes them excellent tracers for volatile transport processes in the Earth's mantle. Experimentally determined fluorine and chlorine partitioning data between mantle minerals and silicate melt enable us to estimate Mid Ocean Ridge Basalt (MORB) and Ocean Island Basalt (OIB) source region concentrations for these elements. This study investigates the effect of varying small amounts of water on the fluorine and chlorine partitioning behavior at 1280 °C and 0.3 GPa between olivine and silicate melt in the Fe-free CMAS+F-Cl-Br-I-H2O model system. Results show that, within the uncertainty of the analyses, water has no effect on the chlorine partitioning behavior for bulk water contents ranging from 0.03 (2) wt% H2O (DCl ol/melt = 1.6 ± 0.9 × 10-4) to 0.33 (6) wt% H2O (DCl ol/melt = 2.2 ± 1.1 × 10-4). Consequently, with the effect of pressure being negligible in the uppermost mantle (Joachim et al. Chem Geol 416:65-78, 2015), temperature is the only parameter that needs to be considered for the determination of chlorine partition coefficients between olivine and melt at least in the simplified iron-free CMAS+F-Cl-Br-I-H2O system. In contrast, the fluorine partition coefficient increases linearly in this range and may be described at 1280 °C and 0.3 GPa with ( R 2 = 0.99): DF^{{ol/melt}} = 3.6± 0.4 × {{10}^{-3}} × {{X}_{{{{H}}_{{2}}}{O}}}( {wt }%) + 6 ± 0.4× {{10}^{-4}}. The observed fluorine partitioning behavior supports the theory suggested by Crépisson et al. (Earth Planet Sci Lett 390:287-295, 2014) that fluorine and water are incorporated as clumped OH/F defects in the olivine structure. Results of this study further suggest that fluorine concentration estimates in OIB source regions are at least 10% lower than previously expected (Joachim et al. Chem Geol 416:65-78, 2015), implying that consideration of the effect of water on the fluorine partitioning

  15. Lamentationes Jeremiae Prophetae de Orlando Di Lasso: algumas figuras retórico-musicais na Lamentatio Prima Primi Diei (Feria Quinta In Coena Domini Orlando Di Lasso' s Lamentationes Jeremiae Prophetae: some rhetorical- musical figures in Lamentatio Prima Primi Diei (Feria Quinta In Coena Domini

    Directory of Open Access Journals (Sweden)

    Áurea Helena de Jesus Ambiel

    2008-12-01

    Full Text Available Este artigo tem como proposta a identificação, na primeira lição das Lamentationes Jeremiae Prophetae, de Orlando Di Lasso (Lamentatio Prima Primi Diei, de figuras retórico-musicais, utilizando a terminologia de época. Para tanto, o trabalho está baseado principalmente na obra Musica Poetica (Rostock, 1606 de Joachim Burmeister, tradução de Benito V. Rivera (Musical Poetics, 1993. A pesquisa faz parte de um projeto de doutorado, que tem como objeto de estudo a obra completa Lamentationes Jeremiae Prophetae (a 5 vozes, que se compõe de três partes: Feria Quinta In Coena Domini, Feria Sexta In Parasceve e Sabbato Sancto. A abordagem analítica de toda a obra deverá seguir a metodologia proposta por Burmeister na sua quinta categoria de análise ("resolução da composição em afetos ou períodos", além de conter observações concernentes ao uso de figuras e outros artifícios retórico-musicais, seguindo  indicações propostas por autores contemporâneos a Lasso que, em muitos casos, citam trechos de suas obras como exemplos para suas colocações. Com o resultado da pesquisa, espera-se fornecer subsídios analíticos que possam reverter em uma interpretação mais segura e historicamente mais bem fundamentada.The aim of this article is to identify rhetorical-musical figures in the first lesson of Orlando Di Lasso's Lamentationes Jeremiae Prophetae (Lamentatio Prima Primi Diei with the terminology used at his period. Thus, the article is based on Joachim Burmeister's Musica Poetica (Rostock, 1606 with the translation into English by Benito V. Rivera (Musical Poetics, 1993.This article is part of a doctoral degree project whose object is the whole Lasso's Lamentationes Jeremiae Prophetae (for five voices which is divided in three parts: Feria Quinta In Coena Domini, Feria Sexta In Parasceve and Sabbato Sancto. The analytical approach of the whole work must follow the methodology proposed by Burmeister in his fifth category of

  16. Regulação social e acumulação por espoliação: reflexão sobre a essencialidade das teses da financeirização e da natureza do estado na caracterização do capitalismo contemporâneo Social regulation and accumulation by spoliation: reflection on the essence of the theses of financialization and the nature of the state in the characterization of contemporary capitalism

    Directory of Open Access Journals (Sweden)

    Niemeyer Almeida Filho

    2011-08-01

    Full Text Available O artigo estrutura-se a partir da interpretação da natureza do capitalismo contemporâneo de David Harvey, particularmente de sua proposição de que esta natureza é essencialmente espoliadora. Esta proposição é confrontada e qualificada pelas teses da financeirização expressas na contribuição de François Chesnais. Daí em diante, mostra-se como a discussão do Estado, de sua forma de operação, sobretudo de suas funções de regulação social, introduz elementos essenciais do "campo político" na caracterização do capitalismo contemporâneo. Neste particular, incorporam-se elementos teóricos de Joachim Hirsch, relativos ao processo de regulação social, mostrando que, para ele, há um "sistema de regulação social" diversificado, que torna o tema da regulação bem mais complexo do que usualmente se reconhece. O artigo busca, assim, mostrar que a associação entre as teses da regulação social e da acumulação por espoliação pode ampliar o escopo de caracterização do processo social de reprodução no capitalismo de hoje, bem como a análise de suas condições de superar as crises.The article is structured from David Harvey's interpretation of the nature of contemporary capitalism, particularly his proposal that this nature is essentially predatory. This proposition is confronted and qualified by the theses of financialization expressed in the contribution by François Chesnais. Thereafter it is shown how the discussion of the State, its mode of operation, especially its functions of social regulation, introduces key elements of "politics fields" in the characterization of contemporary capitalism. In doing so, there is an incorporation of theoretical elements of Joachim Hirsch, concerning the process of social regulation, showing that for him there is a "system of social regulation" diversified, which makes the issue of regulation more complex than usually recognized. The article thus seeks to show that the association

  17. Reaching for Success: Picasso’s Rise in the Market (The First Two Decades

    Directory of Open Access Journals (Sweden)

    Enrique Mallen

    2017-04-01

    Full Text Available This article explores the exhibitions of Picasso’s works in the first two decades of his artistic career, as well as the dealers and collectors who came into contact with them. It describes the relationship between Picasso and his first dealers, Pere Manyach, Berthe Weill, Clovis Sagot, Père Soulier, Ambroise Vollard, Daniel-Henry Kahnweiler, Georg Caspari, L. W. Guthier, Hans Goltz, Heinrich Thannhauser, Otto Feldmann, Alfred Flechtheim, Emil Richter, Gottfried Tanner, Michael Brenner, R. J. Coady, Léonce Rosenberg, Paul Rosenberg, etc.; as well as his first collectors, Leo and Gertrude Stein, Olivier Sainsère, Joachim Gasquet, Wilhelm Uhde, Herman Rupf, Vincenc Kramář, Frank Stoop, Hugo Perls, Edwin Suermondt, Dr. Paul Ferdinand Schmidt, Princess Mechtilde Lichnowsky, Henry Simms, Ludwig and Rosy Fischer, Professor Wilhelm Kreis, Adolf Erblösch, Justin K. Thannhauser, Sergei Ivanovich Shchukin, Ivan A. Morosov, etc. It also identifies all important Picasso expositions in this time period and how those dealers and collectors were involved in their arrangement. The information provided here has been excerpted from an exhaustive study of the critical literature on Pablo Picasso, as well as from published exhibition catalogues.

  18. La finca vitivinícola Guananí: reto y pasión de un empresario. Estudio de caso de la línea de investigación: Historia de empresarios y organizaciones turísticas

    Directory of Open Access Journals (Sweden)

    Ericka Henao Jaramillo

    2006-11-01

    Full Text Available Joachim hezberG es un ingeniero agrónomo de origen Alemán, un hombre carismático, que llegó a Colombia hace más de 20 años para liderar un proyecto del gobierno Alemán, e incorporar variedades de uva a la región de Boyacá. Se enamoró de Villa de Leyva y desde 1985 jalona un proyecto vinícola conocido como Viñedo Guananí, que en lengua indígena significa tierra prometida. Y así es, su viñedo podría considerarse como la tierra prometida para el vino en Colombia. En éste, además del cultivo de la vid y la producción del vino, hay un pequeño hostal y un restaurante que administra en compañía de su esposa. "Juaco el Boyaco", como es conocido en la región, consiente a la caprichosa vid y se da a la difícil tarea de producir vinos en Colombia, un país donde sólo un par de lugares en el Valle del Cauca y en Boyacá tienen las condiciones climáticas y geográficas para la producción de la vid.

  19. Hydrocephalus 2008, 17–20th September, Hannover Germany: a conference report

    Directory of Open Access Journals (Sweden)

    Klinge Petra M

    2008-12-01

    Full Text Available Abstract Hydrocephalus 2008 was held 17–20 September in Hannover, Germany, at the invitation of Petra M Klinge (President, co-hosted by Joachim K. Krauss (Vice President, and Madjid Samii (Honorary President. This meeting was a successor to Hydrocephalus 2006 held in Göteborg, Sweden, organised by Past-President, Carsten Wikkelso. The conference began with a general introductory session of six talks including three invited lectures, followed by eighteen parallel sessions. Subjects covered were hydrocephalus signs, symptoms and diagnosis, especially in normal pressure hydrocephalus; cerebrospinal fluid (CSF physics and dynamics; CSF function and modelling of function; dementia and quality of life, economy, health care and rehabilitation; neuropsychology, cognition and outcome assessment; neuroimaging, functional imaging and non-invasive diagnostics; paediatric and adolescent hydrocephalus; intelligent shunt and valve design (e.g. telemetry, adjustable and antimicrobial shunts; endoscopic third ventriculostomy; technical advances and image-guided surgical approaches in the treatment of hydrocephalus; brain metabolism, biomarkers and biophysics; co-morbidity, classification and aetiology; epidemiology, registries and clinical trials; experimental hydrocephalus; and pharmaceutical modulation of central nervous system function (CNS drug delivery. Each session began with introductory talks from the invited chairpersons followed by six to eight submitted oral presentations. Overall, 136 oral presentations and 18 posters were presented, the abstracts of which were published elsewhere 1. We present here an account of the introductory session, the invited chairperson's talks and the concluding remarks by Anthony Marmarou.

  20. Endoplasmic reticulum-mitochondria calcium signaling in hepatic metabolic diseases.

    Science.gov (United States)

    Rieusset, Jennifer

    2017-06-01

    The liver plays a central role in glucose homeostasis, and both metabolic inflexibility and insulin resistance predispose to the development of hepatic metabolic diseases. Mitochondria and endoplasmic reticulum (ER), which play a key role in the control of hepatic metabolism, also interact at contact points defined as mitochondria-associated membranes (MAM), in order to exchange metabolites and calcium (Ca 2+ ) and regulate cellular homeostasis and signaling. Here, we overview the role of the liver in the control of glucose homeostasis, mainly focusing on the independent involvement of mitochondria, ER and Ca 2+ signaling in both healthy and pathological contexts. Then we focus on recent data highlighting MAM as important hubs for hormone and nutrient signaling in the liver, thus adapting mitochondria physiology and cellular metabolism to energy availability. Lastly, we discuss how chronic ER-mitochondria miscommunication could participate to hepatic metabolic diseases, pointing MAM interface as a potential therapeutic target for metabolic disorders. This article is part of a Special Issue entitled: ECS Meeting edited by Claus Heizmann, Joachim Krebs and Jacques Haiech. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. QUEM ESTÁ NO COMANDO? NEUROCIÊNCIA, RESSONÂNCIA E DESAFIOS PARA A TEOLOGIA

    Directory of Open Access Journals (Sweden)

    Rudolf von Sinner

    2018-02-01

    ABSTRACT: The relationship between body and soul or between body, soul and spirit is an ancient problem of anthropology, and also of Christian theology. In view of present day discoveries and new neuroscientific theories, the issue poses itself afresh. It practically migrated to the discussion of the relationship between brain and mind. Today, there is ample consensus that it is the brain that is in charge of the body. If we accept that, then who is in charge of the brain? Is it me, in the first person, my soul, my mind? Or is it “him”, in the third person, our own brain that determines me? And how about the second person – the human being in its relationship with God whom it calls “you”? Striving to overcome prejudices against a deterministic neuroscience, on the one hand, and a theology indifferent to science – and, indeed, such positions, wherever they are held – the present article seeks to deal with the human condition in its freedom, always precarious and restrained. Referring to neurobiological and psychiatric insights from Joachim Bauer, it argues for the importance of the relationship of the human being with the other, with God and with the world, in a form of resonance (Hartmut Rosa.

  2. Quark Matter 2011 (QM11) Quark Matter 2011 (QM11)

    Science.gov (United States)

    2011-12-01

    International Advisory Committee Antinori, FedericoPaic, Guy Braun-Munzinger, PeterPajares, Carlos Cifarelli, LuisaPeitzmann, Thomas Erazmus, BarbaraRedlich, Krzysztof Eskola, KariRiccati, Lodovico Gaardhøje, Jens JørgenRoland, Gunther Gale, CharlesRoy, Christelle Gelis, FrancoisSchukraft, Jürgen Giubellino, PaoloSinha, Bikash Greiner, CarstenSrivastava, Dinesh Gyulassy, MiklosStachel, Johanna Harris, JohnSteinberg, Peter Hatsuda, TetsuoStroth, Joachim Heinz, UlrichSugitate, Toru Jacak, BarbaraTserruya, Itzhak Karsch, FrithjofVelkovska, Julia Kharzeev, DimaWang, Enke Kodama, TakeshiWang, Xin, Nian Lévai, PéterWessels, Johannes Manko, VladislavXu, Nu Müller, BerndtZajc, William Ollitrault, Jean-Yves Organizing Committee Arleo, FrancoisDupieux, Pascal Bastid, NicoleFurget, Christophe Bourgeois, Marie-LaureGranier de Cassagnac, Raphael Bregant, MarcoGuernane, Rachid Carminati, FedericoHervet, Carnita Castillo, JavierKuhn, Christian Cheynis, BrigitteOlivier, Nathalie Conesa, DelValle, Zaida Connor, MichelleRenshall, Lucy Crochet, PhilippeSuire, Christophe Delagrange, HuguesTihinen, Ulla Program Committee Schutz, Yves (Chair)Baldisseri, Alberto Wiedemann, Urs (co-Chair)Safarik, Karel Aurenche, Patrick

  3. Marcel Odenbach. Konzept, Performance, Video, Installation 1975 – 1998

    DEFF Research Database (Denmark)

    Kacunko, Slavko

    of video art, considering its cognitive, technical and aesthetic aspects. To have documented in such cogent – and comprehensive – a manner the significance of the video artist Marcel Odenbach and what sets his oeuvre apart, is in itself a considerable feat. But the insights so gained go beyond his oeuvre.......000 marks, à la puplication et à la diffusion de la thèse. Joachim Erwin, premier maire de Düsseldorf et prèsident du conseil de surveillance de Messe Düsseldorf, et Albrecht Bolza-Schünemann, prèsident de drupa 2000 et prèsident adjoint du directoire de Koenig & Bauer AG, remettront le document officiel à...... soddisfatto per la scelta dell`argomento. “Il Dr. Kacunko affronta in sostanza la medesima questine che occupa ormai de anni anche il settore della stampa e dei media ovvero quella relativa alla gestione dei nuovi mezzi di comunicazione e allo sfruttamento del loro potenziale tecnico e creativo.”. Il Dr...

  4. Theology of Arnold of Villanova: between Bible and politics

    Directory of Open Access Journals (Sweden)

    Bogusław Kochaniewicz

    2011-09-01

    Full Text Available Biblical interpretation of Arnold of Villanova manifests us not only a specific and particular current of exegesis within 14th century. He emphasised the idea of eschaton fullfilled, manifested through the history more and more clear and perfect. His exegesis, based on Joachim de Fiore’s work presented the Bible as an instrument of the historical knowledge. The Bible, interpreted in allegorical perspective, manifested the meaning of the events pasted and presents and future. In order that Bible could be always actual, it required miracles and apparitions, which would support and manifest extraordinary divine interventions within the history of the world. In Arnold’s opinion, the Bible, without miracles and mistical experiences, could lost its own meaning. Arnold of Villanova, being inspired by the Franciscan spiritual movement, strived to evidence the ideas of the nearness of the end of the world. Even if he was not an eminent theologian, he impressed and inspired his epoch. Therefore his name is mentioned by the manuals of the history of theology.

  5. The place of the 17th century in Jung's encounter with China.

    Science.gov (United States)

    Cambray, Joe

    2005-04-01

    After recounting several dreams and related alchemical interests of Jung's tied to the 17(th) century, a contextualizing look at select scientific and philosophical developments of that century is presented. Several precursors of the contemporary debates on the mind/body relation are noted, with special reference to the work of Antonio Damasio. This in turn leads to a reconsideration of the work of the 17(th) century polymath Gottfried Wilhelm Leibniz, which Jung read as a major precursor to his formulation of synchronicity (via Leibniz's concept of 'pre-established harmony'). Leibniz was the first philosopher to articulate the mind/body relationship in terms of supervenience, sharing an accord with those contemporary philosophers and scientists who see the mind as being an emergent property of the body-brain. Similarly, these ideas are also consistent with a reformulation of synchronicity in terms of emergence. Tracing Leibniz's interest in China reveals another set of links to Jung and to emergentism. Jung's use of Taoist concepts in developing the synchronicity principle is well known. According to scholars, Leibniz was the first major Western intellect to study the I-Ching, through the assistance of a Jesuit missionary in Beijing, Fr. Joachim Bouvet. Some details of the Leibniz-Bouvet correspondence are discussed here. Despite Helmut Wilhelm's presenting aspects of this correspondence at an Eranos conference, Jung does not appear to have integrated it into his writing on synchronicity--a possible reason for this omission is suggested.

  6. Energy management for cost reduction in the production. TEEM - Total Energy Efficiency Management; Energiemanagement zur Kostensenkung in der Produktion. TEEM - Total Energy Efficiency Management

    Energy Technology Data Exchange (ETDEWEB)

    Westkaemper, Engelbert; Verl, Alexander (eds.)

    2009-07-01

    Within the workshop of the Fraunhofer Institute for Manufacturing Engineering and Automation IPA (Stuttgart, Federal Republic of Germany) at 6th October, 2009, in Stuttgart the following lectures were held: (1) Presentation of Fraunhofer Institute for Manufacturing Engineering and Automation IPA (Engelbert Westkaemper); (2) TEEM - Total Energy Efficiency Management - ''With energy management to an energy efficient production'' (Alexander Schloske); (3) DIN EN 16001 Introduction of an energy management system - utilization and advantages for companies (Sylvia Wahren); (4) Analysis of the energy efficiency with power flow - Support and implementation at factory planning and optimization of production (Klaus Erlach); (5) Total Energy Efficiency Management - Approaches at the company Kaercher in injection moulding for example (Axel Leschtar); (6) Modelling the embodied product energy (Shahin Rahimifard); (7) Acquisition of energy data in the production - Technologies and possibilities (Joachim Neher); (8) Active energy management by means of an ''energy control centre'' - Analysis of the real situation and upgrading measures in the production using coating plants as an example (Wolfgang Klein); (9) Visualisation and simulation of energy values in the digital factory (Carmen Constantinescu, Axel Bruns).

  7. Successfull operation of biogas plants. Data acquisition as a basis of successful optimization measures; Erfolgreicher Betrieb von Biogasanlagen. Datenerfassung als Grundlage erfolgreicher Optimierungsmassnahmen

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-09-19

    Within the 2nd Bayreuth expert meeting on biomass at 6th June, 2012 in Bayreuth (Federal Republic of Germany), the following lectures were held: (1) Presentation of the activities in the bio energy sector of the Landwirtschaftliche Lehranstalt Bayreuth (Rainer Prischenk); (2) State of the art of utilizing biogas in Oberfranken from the view of FVB e.V. (Wolfgang Holland Goetz); (3) Optimization of the plant operation by means of an intelligent control (Christian Seier); (4) Process optimization by means of identification of losses of biogas and evaluation of the load behaviour and emission behaviour of gas engines (Wolfgang Schreier); (5) Data acquisition and implementation of optimization measures from the point of view of an environmental verifier (Thorsten Grantner); (6) Economic analysis and optimization by means of the Lfl program BZA Biogas (Josef Winkler); (7) Detailed data acquisition as a necessary basis of the process optimization (Timo Herfter); (8) Case examples of the biologic support of biogas plants and their correct evaluation (Birgit Pfeifer); (9) A systematic acquisition of operational data as a basis for the increase of efficiency using the Praxisforschungsbiogasanlage of the University Hohenheim (Hans-Joachim Naegele); (10) Practical report: The biogas plant Sochenberg towards 100% utilization of energy (Uli Bader).

  8. L’Eglise de l’hopital du monastère Brâncoveni (Département Olt. Recherches iconographiques / The Church of the Hospital from Brancoveni Monastery (Olt County. Iconographic Research

    Directory of Open Access Journals (Sweden)

    Tereza Sinigalia

    2016-11-01

    Full Text Available The present paper aims to provide information on the recent restoration of the murals inside the small church of the „Bolniţa” (Romanian word for a chapel lying next to a monastic hospital of the Brâncoveni Monastery (Department Olt, built by the Prince of Wallachia Constantin Brâncoveanu in 1700. All the inside of the church was covered with frescoes, but my attention focused on the paintings in the narthex. As the church is dedicated to The Archangels, the upper part of the walls is covered with 10 compositions illustrating facts from the Ancient Testament and from the inter-testamental texts in which Angels Michael et Gabriel were involved: The Sacrifice of Abraham, Lot and the destruction of Sodom; Prophet Gideon; The Fake Prophet Balaam; Prophet Daniel and the dream of the king Nabucodonosor; The dream of the Prophet Elijah; Archangel Gabriel announces Zacharias and his wife Elisabeth about the birth of a son, the future John the Baptist; Archangel Gabriel announces Joachim and Ann about the birth of a daughter, Mary; Archangel Gabriel advises Joseph to take Mary as his fiancé; Annunciation. A huge Votive composition of the ancestors of the Prince Constantin Brâncoveanu (grandfather, father, grand uncle, the Prince Matei Basarab and his father is painted on the lower register of the room. Princess Maria, Brâncoveanu’s wife, is present, too.

  9. O fogo é o agente, que causa tantas maravilhas A América e as explosões subterrâneas na História Universal dos Terremotos de 1758

    Directory of Open Access Journals (Sweden)

    Jorge FERREIRA

    Full Text Available Resumo Esse artigo comenta a obra A História Universal dos Terremotos, o primeiro catálogo sísmico elaborado em língua portuguesa, escrita por Joachim José Moreira de Mendonça na sequência do Grande Terremoto de Lisboa (GTL de 1755. O artigo considera os argumentos de Moreira de Mendonça como evidências em favor da convivência de diversas teorias modernas e mudanças de entendimento em relação aos sismos. A partir da catalogação de sismicidades em escala planetária e de seus efeitos enumerados pelo autor, o artigo destaca as ocorrências sísmicas registradas, no continente americano, considerando que a sismicidade distribuída no tempo e no espaço foi o ponto de partida para o estudo sismológico de Moreira de Mendonça. Aborda ainda sua explicação para as causas dos terremotos, apoiada nas idéias de ação do fogo subterrâneo, considerando que Moreira de Mendonça em seu catálogo trata os terremotos como desastres naturais no contexto da cultura científica de sua época.

  10. Bcl-2 regulation of the inositol 1,4,5-trisphosphate receptor and calcium signaling in normal and malignant lymphocytes: potential new target for cancer treatment.

    Science.gov (United States)

    Greenberg, Edward F; Lavik, Andrew R; Distelhorst, Clark W

    2014-10-01

    The anti-apoptotic protein Bcl-2 is a versatile regulator of cell survival. Its interactions with its own pro-apoptotic family members are widely recognized for their role in promoting the survival of cancer cells. These interactions are thus being targeted for cancer treatment. Less widely recognized is the interaction of Bcl-2 with the inositol 1,4,5-trisphosphate receptor (InsP3R), an InsP3-gated Ca(2+) channel located on the endoplasmic reticulum. The nature of this interaction, the mechanism by which it controls Ca(2+) release from the ER, its role in T-cell development and survival, and the possibility of targeting it as a novel cancer treatment strategy are summarized in this review. This article is part of a Special Issue entitled: Calcium signaling in health and disease. Guest Editors: Geert Bultynck, Jacques Haiech, Claus W. Heizmann, Joachim Krebs, and Marc Moreau. Copyright © 2014 Elsevier B.V. All rights reserved.

  11. CRAC channels, calcium, and cancer in light of the driver and passenger concept.

    Science.gov (United States)

    Hoth, Markus

    2016-06-01

    Advances in next-generation sequencing allow very comprehensive analyses of large numbers of cancer genomes leading to an increasingly better characterization and classification of cancers. Comparing genomic data predicts candidate genes driving development, growth, or metastasis of cancer. Cancer driver genes are defined as genes whose mutations are causally implicated in oncogenesis whereas passenger mutations are defined as not being oncogenic. Currently, a list of several hundred cancer driver mutations is discussed including prominent members like TP53, BRAF, NRAS, or NF1. According to the vast literature on Ca(2+) and cancer, Ca(2+) signals and the underlying Ca(2+) channels and transporters certainly influence the development, growth, and metastasis of many cancers. In this review, I focus on the calcium release-activated calcium (CRAC) channel genes STIM and Orai and their role for cancer development, growth, and metastasis. STIM and Orai genes are being discussed in the context of current cancer concepts with a focus on the driver-passenger hypothesis. One result of this discussion is the hypothesis that a driver analysis of Ca(2+) homeostasis-related genes should not be carried out by looking at isolated genes. Rather a pool of “Ca(2+) genes” might be considered to act as one potential cancer driver. This article is part of a Special Issue entitled: Calcium and Cell Fate. Guest Editors: Jacques Haiech, Claus Heizmann, Joachim Krebs, Thierry Capiod and Olivier Mignen.

  12. CERN honours Carlo Rubbia

    CERN Multimedia

    2009-01-01

    On 7 April CERN will be holding a symposium to mark the 75th birthday of Carlo Rubbia, who shared the 1984 Nobel Prize for Physics with Simon van der Meer for contributions to the discovery of the W and Z bosons, carriers of the weak interaction. Following a presentation by Rolf Heuer, lectures will be given by eminent speakers on areas of science to which Carlo Rubbia has made decisive contributions. Michel Spiro, Director of the French National Institute of Nuclear and Particle Physics (IN2P3) of the CNRS, Lyn Evans, sLHC Project Leader, and Alan Astbury of the TRIUMF Laboratory will talk about the physics of the weak interaction and the discovery of the W and Z bosons. Former CERN Director-General Herwig Schopper will lecture on CERN’s accelerators from LEP to the LHC. Giovanni Bignami, former President of the Italian Space Agency and Professor at the IUSS School for Advanced Studies in Pavia will speak about his work with Carlo Rubbia. Finally, Hans Joachim Sch...

  13. CERN honours Carlo Rubbia

    CERN Document Server

    2009-01-01

    On 7 April CERN will be holding a symposium to mark the 75th birthday of Carlo Rubbia, who shared the 1984 Nobel Prize for Physics with Simon van der Meer for contributions to the discovery of the W and Z bosons, carriers of the weak interaction. Following a presentation by Rolf Heuer, lectures will be given by eminent speakers on areas of science to which Carlo Rubbia has made decisive contributions. Michel Spiro, Director of the French National Institute of Nuclear and Particle Physics (IN2P3) of the CNRS, Lyn Evans, sLHC Project Leader, and Alan Astbury of the TRIUMF Laboratory will talk about the physics of the weak interaction and the discovery of the W and Z bosons. Former CERN Director-General Herwig Schopper will lecture on CERN’s accelerators from LEP to the LHC. Giovanni Bignami, former President of the Italian Space Agency, will speak about his work with Carlo Rubbia. Finally, Hans Joachim Schellnhuber of the Potsdam Institute for Climate Research and Sven Kul...

  14. Formal values and the essence of art

    Directory of Open Access Journals (Sweden)

    Ulrich Pfisterer

    2011-12-01

    Full Text Available Review of: Paul van den Akker, Looking for Lines. Theories on the Essence of Art and the Problem of Mannerism, Amsterdam: Amsterdam University Press 2010. The problem of the categorical definition of the nature of art was often regarded as the central challenge of art history. Paul van den Akker examines the history of this problem from the eighteenth century to the 1960s. Thus his book addresses ‘the essence of art history’. In order to do so, he uses the extremely contradictory discussions of ‘Mannerism’ and the use of the line in mannerist art as a relevant case study, and this is supplemented with extensive excursuses on historic concepts of ‘classical art’, of Renaissance painting, of medieval art, or connoisseurship. Johann Joachim Winckelmann, Heinrich Wölfflin, Alois Riegl and John Shearman play key roles in van den Akker’s book. The review mainly asks for the specificity of the analytical categories and the changing role of the visual material used by the antiquarians and early art historians from the later seventeenth to the early twentieth centuries to illustrate and accompany their texts and arguments.

  15. At the Bottom of the Garden: The Caffeaus of Villa Albani

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    Jane Lomholt

    2014-02-01

    Full Text Available This paper addresses the history and design of a pavilion at the Villa Albani in Rome. Built in 1764 by the architect Carlo Marchionni, possibly to a design by the client, the antiquarian Cardinal Alessandro Albani, this is a caffeaus (or coffee house, to offer a rough translation featuring an eleven-bay semi-circular portico of Doric order. The taking of coffee after dinner had become a popular pastime and some, who could afford it, built special pavilions in their gardens for this purpose. Pope Benedict XIV, for instance, had a caffeaus built in his garden at the Quirinal Palace some twenty years earlier, where he could withdraw from the formalities of courtly life. For Cardinal Albani, the caffeaus also served as an extension to his Casino, where his vast collection of sculptures, busts and basins was displayed. With the aid of his librarian, the German scholar and writer Johann Joachim Winckelmann, Albani displayed his immense and unique collection of art and antiquities in a way that served to underline his own scholarship, wealth and position of affinity with Rome. The Villa and its splendours were not to be missed by the Grand Tourists. This paper will situate this exceptional pavilion in the wider context of his Villa, whose gardens and buildings today lie in various stages of disrepair and are closed to the public, except by private invitation.

  16. “The Boy and the Blade of Grass”: trajectories of children’s music making

    Directory of Open Access Journals (Sweden)

    Teca Alencar de Brito

    2012-01-01

    Full Text Available This article relates the trajectories of children’s music making to the Estética do Impreciso e do Paradoxal (Aesthetics of the Imprecise and Paradoxical, proposed by the German musician Hans Joachim Koellreutter (1915-2005 and to the concepts of musicality and sonority suggested by the French composer Pierre Schaeffer (1910-1995. Such an analysis, which is included in the doctoral thesis that I defended for the Communications and Semiotics Program at the Pontifical University of São Paulo (2007, proposes to expand discussions and thought regarding children’s relationship to sounds and music, aiming to validate and signify the routes of such occurrences. Reporting back to the concept of mino literature proposed by Gilles Deleuze (1925-1995 and Félix Guattari (1930-1992, the article points towards a minor mode of thinking about/making music in early childhood: a singular mode that reveals the singularity and dynamic transformation of the ideas of music, considering the gains in complexity that surround the process of development as a whole. A mode that is captured by the great systems that are dominant in a culture’s music production, as well as the territories of music education. In conclusion, I point towards the need to institute open-ended plans that dialogue with tradition, experimentation, “make believe,” and, in short, plans of possibilities that permeate children’s relationship to sounds and music

  17. [Critical notions about Paracelsus [corrected] or "Antiparacelsianism"?, 1570-1630].

    Science.gov (United States)

    Walter, Tilmann

    2008-01-01

    Historians of early modern medicine have frequently portrayed Paracelsians and Antiparacelsians around 1600 as two largely separate, hostile factions locked in a fierce battle. As I will argue in my paper, this account attributes too much weight to the public self-fashioning of both groups: From the mid-16th century onwards, some physicians chose the deceased Theophrastus of Hohenheim, or Paracelsus, as their new medical hero and tried to attract affluent patients with new, supposedly more powerful "spagyric" medicaments. Other physicians showed intense interest without thereby accepting Paracelsus as the "Luther of medicine". Based on my analysis of large collections of early modern physicians' letters, I argue for a more nuanced and cautious account of this conflict. Well-known physicians like Konrad Gesner, Johann Crato von Krafftheim, or Joachim Camerarius did indeed condemn the arrogance and rudeness of Paracelsus and his belittling of the ancient medical authors. Yet, at the same time, they also showed a keen interest in the new chemical drugs which the "Paracelsians" promoted. None of these supposed "Antiparacelsians" supported or welcomed the vehement attacks by Thomas Erastus in his Disputationum de Medicina nova Paracelsi without reservations--although Erastus suggested this for tactical reasons.

  18. FROM THE SIGNIFICANT ST. JOACHIMSTAL SILVER AND URANIUM PIT, JÁCHYMOV, TO RADON SPA IN SAXON CZECH „RUDNA GORA“

    Directory of Open Access Journals (Sweden)

    Branislav Šebečić

    2006-12-01

    Full Text Available At he beginning of the 16th century Saxon miners discovered silver ore in the small settlement Konnradsgrűn at south-west slopes of Erzgebirge in the valley Joachimsthal named after the patron saint St. Joachim. The silver coin was named Jochymst(haler. The mine and the settlement became a free royal mining city where, thanks to the mint, one of the richest noble families von Schlick arose. 554,44 tons of silver were produced from 1517 till 1900. Together with silver ore cobalt and lead ore were exploited ( in significant quantities from 18th till 19th century and after that period nickel, bismuth and arsenic ore (19th century. From the listed ores cobalt was produced in largest quantities for enamel production; 1824,23 tons in the period from 1775 till 1851. Next to these ores uranite ore (urani/ni/t was discovered in the mine. The ore was first used to produce uranium colours used for ceramics, glass and paintings and later to obtain uranium; 8500 tons since 1853 till 1964, a part of which was worked up into radium, to obtain 100gr Ra-. Thanks to the discovery of radioactive- radon water the mine is still active because 20 miners are employed to maintain the part of it from which the radon water is exploited. Jachymov and its surroundigs have become a famous radioactive thermal sanatorium in Europe (the paper is published in Croatian.

  19. Assessing Various Aspects of Sustainability in Wheat and Pistachio Agro-ecosystems of Kerman Province

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    Mehdi Naghizadeh

    2018-02-01

    questionnaires were completed for wheat and pistachio, respectively. Farms were selected randomly. Data were analyzed using Excel and SAS software. Results and Discussion The Study of individual characteristics of farmers showed that the average age of farmers for wheat and pistachios production systems was about 43 and 39 years respectively. Age was considered as an important factor in displaying the features of one’s personality. Therefore, young group is more zealous and earnest in their work and can handle farming activities more efficiency. In both studied systems, those who had high school education had the highest frequency. Education may enhance farm productivity directly by improving the quality of labor, increasing the ability to adjust to disequilibria, and through its effect upon the propensity to adopt innovation successfully. Average yield was reported 3460 kg ha-1for wheat and 573 kg ha-1for pistachios. Crop production is an indicator of system efficiency, in regard to genetic potential, ecological conditions, management, capital investment and labor use. The results showed that, unfortunately, the fertilizer and chemical inputs, especially in pistachio, is extremely high, which is inconsistent with the approaches of sustainable agriculture. The average annual income in wheat and pistachio was gained 4 and 18 million tooman, respectively. Non-agricultural income sources make sure to provide sufficient income to the farmers. Reduction in rural incomes will lead to different immigration outcomes. Family economic security directly affects on the economic sustainability of agriculture. Assessing various sustainability indicators showed that the sustainability index in wheat and pistachio was 47.2 and 44.2, respectively, and also that these agro-ecosystems are not sustainable. Crop residue management indicator in wheat and socio-economic in pistachios production systems had a better condition than other indicators. The results indicated that chemical inputs

  20. Reliability of an e-PRO Tool of EORTC QLQ-C30 for Measurement of Health-Related Quality of Life in Patients With Breast Cancer: Prospective Randomized Trial.

    Science.gov (United States)

    Wallwiener, Markus; Matthies, Lina; Simoes, Elisabeth; Keilmann, Lucia; Hartkopf, Andreas D; Sokolov, Alexander N; Walter, Christina B; Sickenberger, Nina; Wallwiener, Stephanie; Feisst, Manuel; Gass, Paul; Fasching, Peter A; Lux, Michael P; Wallwiener, Diethelm; Taran, Florin-Andrei; Rom, Joachim; Schneeweiss, Andreas; Graf, Joachim; Brucker, Sara Y

    2017-09-14

    differences were found in 27 of 30 single items and in 14 of 15 scales, whereas a statistically significant correlation in the test of consistency was found in all 30 single items and all 15 scales. The evaluated e-PRO version of the EORTC QLQ-C30 is reliable for patients with both adjuvant and metastatic breast cancer, showing a high correlation in almost all questions (and in many scales). Thus, we conclude that the validated paper-based PRO assessment and the e-PRO tool are equally valid. However, the reliability should also be analyzed in other prospective trials to ensure that usability is reliable in all patient groups. ClinicalTrials.gov NCT03132506; https://clinicaltrials.gov/ct2/show/NCT03132506 (Archived by WebCite at http://www.webcitation.org/6tRcgQuou). ©Markus Wallwiener, Lina Matthies, Elisabeth Simoes, Lucia Keilmann, Andreas D Hartkopf, Alexander N Sokolov, Christina B Walter, Nina Sickenberger, Stephanie Wallwiener, Manuel Feisst, Paul Gass, Peter A Fasching, Michael P Lux, Diethelm Wallwiener, Florin-Andrei Taran, Joachim Rom, Andreas Schneeweiss, Joachim Graf, Sara Y Brucker. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 14.09.2017.

  1. Skin-protective effects of a zinc oxide-functionalized textile and its relevance for atopic dermatitis

    Directory of Open Access Journals (Sweden)

    Wieg

    2013-05-01

    Full Text Available Cornelia Wiegand,1 Uta-Christina Hipler,1 Sebastian Boldt,2 Joachim Strehle,2 Uwe Wollina21Department of Dermatology, University Medical Center Jena, Jena, Germany; 2Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, GermanyAbstract: Atopic dermatitis (AD is a chronic inflammatory disease characterized by the impairment of the skin-barrier function, increased oxidative cellular stress, and bacterial colonization. Hence, medical therapies of AD aim to control infection, reduce inflammation, and restore skin-barrier function by use of topical and systemic antibacterial drugs, topical corticosteroids, topical calcineurin inhibitors, and moisturizers. Textiles have the longest and most intense contact with the human skin, and functional textiles with intrinsic properties such as antioxidative capacity and antibacterial activity have been gaining in importance in medical applications. Specially designed textiles may support AD treatment and improve quality of life of AD. Here, we investigated the role of ZnO-functionalized textile fibers in the control of oxidative stress in AD in vitro and in vivo. In addition, the antibacterial effect and biocompatibility of the Zn textile was evaluated in vitro. We observed a rapid improvement of AD severity, pruritus, and subjective sleep quality when AD patients wore the ZnO textiles overnight on 3 consecutive days. This is possibly due to the high antioxidative capacity of the ZnO textile, as well as the allocation of strong antibacterial activity. Moreover, it was shown that the ZnO textiles possess very good biocompatibility and were well tolerated by AD patients.Keywords: atopic dermatitis, antibacterial activity, biocompatibility, functionalized textiles, oxidative stress

  2. German Emergency Care in Neurosurgery and Military Neurology during World War II, 1939-1945.

    Science.gov (United States)

    Stahnisch, Frank W

    2016-01-01

    A critical analysis of the historical involvement of neurology and neurosurgery in military emergency care services enables us to better contextualize and appreciate the development of modern neurology at large. Wartime neurosurgery and civil brain science during the German Nazi period tightly coalesced in examining the specific injury types, which military neurosurgeons such as Wilhelm Toennis, Klaus Joachim Zuelch, and Georg Merrem encountered and treated based on their neurophysiological understanding gained from earlier peacetime research. Collaborative associations with Dr. Toennis in particular proved to be highly beneficial to other military neurologists and neurosurgeons during World War II and beyond. This article also discusses the prewar developments and considers the fate of German neurosurgeons and military neurologists after the war. The envisaged dynamic concepts of fast action, reaction, and recycling, which contemporary physicians had intensively studied in the preceding scientific experiments in their neurophysiological laboratories, had already been introduced into neurological surgery during the interwar period. In retrospect, World War II emergency rescue units greatly strengthened military operations through an active process of 'recycling' indispensable army personnel. Neurosurgical emergency chains thereby introduced another decisive step in the modernization of warfare, in that they increased the momentum of military mobility in the field. Notwithstanding the violence of warfare and the often inhumane ways in which such knowledge in the field of emergency neurology was gained, the protagonists among the group of experts in military neurology and neurosurgery strongly contributed to the postwar clinical neuroscience community in Germany. In differing political pretexts, this became visible in both East Germany and West Germany after the war, while the specific military and political conditions under which this knowledge of emergency medicine

  3. Efficacy of antibiotic treatment of implant-associated Staphylococcus aureus infections with moxifloxacin, flucloxacillin, rifampin, and combination therapy: an animal study

    Directory of Open Access Journals (Sweden)

    Greimel F

    2017-06-01

    Full Text Available Felix Greimel,1 Christine Scheuerer,1 Andre Gessner,2 Michaela Simon,2 Thomas Kalteis,1 Joachim Grifka,1 Achim Benditz,1 Hans-Robert Springorum,1 Jens Schaumburger1 1Department of Orthopedics, University Medical Center Regensburg, Asklepios Klinikum Bad Abbach, Bad Abbach, 2Institute of Clinical Microbiology and Hygiene, University Medical Center Regensburg, Regensburg, Bavaria, Germany Abstract: The efficacy of antibiotic monotherapy and combination therapy in the treatment of implant-associated infection by Staphylococcus aureus was evaluated in an animal study. The femoral medullary cavity of 66 male Wistar rats was contaminated with S. aureus (ATCC 29213 and a metal device was implanted, of which 61 could be evaluated. Six treatment groups were studied: flucloxacillin, flucloxacillin in combination with rifampin, moxifloxacin, moxifloxacin in combination with rifampin, rifampin, and a control group with aqua. The treatment was applied for 14 days. After euthanasia, the bacterial counts in the periprosthetic bone, the soft tissue, and the implant-associated biofilm were measured. Both antibiotic combination treatments (moxifloxacin plus rifampin and flucloxacillin plus rifampin achieved a highly significant decrease in microbial counts in the bone and soft tissue and in the biofilm. Mono-antibiotic treatments with either moxifloxacin or flucloxacillin were unable to achieve a significant decrease in microbial counts in bone and soft tissue or the biofilm, whilst rifampin was able to reduce the counts significantly only in the biofilm. Antibiotic resistance was measured in 1/3 of the cases in the rifampin group, whereas no resistance was measured in all other groups. The results show that combinations of both moxifloxacin and flucloxacillin plus rifampin are adequate for the treatment of periprosthetic infections due to infections with S. aureus, whereas monotherapies are not effective or not applicable due to the rapid development of

  4. The Secularization of the Estates of the Eastern Monasteries and Churches in Wallachia and Moldavia in the Early 1860-s and Russia

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    Gerd Lora

    2014-12-01

    Full Text Available The article is the fi rst attempt to trace in details, basing on inedited archive materials from Russian and Rumanian archives, the history of the secularization of the so called “inclined” monastic properties in the united principalities of Moldavia and Wallachia during the reign of Alexander Kuza. Attempts (though without any suffi cient result to reduce the rights of the foreign owners of the estates (1/4 of the territory of the country were undertaken already in the fi rst half of the 19th century. After the Crimean war with weakening of Russian infl uence and strengthening of French one such an action could count on better results. According to Protocol 13 of the Paris Conference of 1858 the Principalities should have solved their problem with the Greek owners of the properties. In case of misunderstanding an international commission consisting of commissioners from the powers had to take place. Such a commission started its work in Constantinople in 1862, and as it’s well preserved documentation shows, did not bring any positive result. Russia was the only to support the rights of the Greek owners, while the position of Britain and Austria was wavering, and France was in open opposition to any actions against the secularization. The inconsistent behavior of the Greek Patriarchs and the attempts of Patriarch Joachim II to turn the aff air in his own benefi t only was in the way of solution of the question. Another idea, of a monetary compensation for the estates was not carried through either, though the Greek bankers of Constantinople seemed ready to support it. Meanwhile Kuza, basing on the support of Napoleon III, carried through the fi nal confi scation of the lands. This act became one of the most suffi cient in his policy for unifi cation of Rumania and creating an independent national state.

  5. Controlled-release nanoencapsulating microcapsules to combat inflammatory diseases

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    Baek JS

    2017-06-01

    Full Text Available Jong-Suep Baek,1 Eng Wan Yeo,1 Yin Hao Lee,2 Nguan Soon Tan,2 Say Chye Joachim Loo1,3 1School of Materials Science and Engineering, Nanyang Technological University, Singapore; 2School of Biological Sciences, Nanyang Technological University, Singapore; 3Singapore Centre on Environmental Life Sciences Engineering (SCELSE, Nanyang Technological University, Singapore Abstract: The World Health Organization (WHO has reported that globally 235 million people suffer from chronic and other inflammatory diseases. The short half-lives of nonsteroidal anti-inflammatory drugs (NSAIDs and their notoriety in causing gastrointestinal discomforts, warrants these drugs to be released in a controlled and sustained manner. Although polymeric particles have been widely used for drug delivery, there are few reports that showcase their ability in encapsulating and sustaining the release of NSAIDs. In this paper, polymeric nanoencapsulating microcapsules loaded with NSAIDs were fabricated using solid/water/oil/water emulsion solvent evaporation method. Two NSAIDs, ibuprofen and naproxen, were first pre-loaded into nanoparticles and then encapsulated into a larger hollow microcapsule that contained the third NSAID, celecoxib. A high encapsulation efficiency (% of these NSAIDs was achieved and a sustained release (up to 30 days of these drugs in phosphate-buffered saline was observed. Then, a gastrointestinal drug – cimetidine (CIM – was co-loaded with the NSAIDs. This floating delivery system exhibited excellent buoyancy (~88% up to 24 h in simulated gastric fluid. It also allowed a sequential release of the drugs, whereby an immediate release of CIM followed by NSAIDs was observed. Drug release of the NSAIDs observed Fickian diffusion mechanism, whereas CIM observed non-Fickian diffusion. Therefore, this delivery system is a promising platform to control the delivery of NSAIDs to combat inflammatory diseases, thereby protecting against possible gastrointestinal

  6. PREFACE: The Science of Making Torque from Wind 2012

    Science.gov (United States)

    2014-12-01

    The European Academy of Wind Energy (eawe) was pleased to announce its 4th scientific conference The Science of Making Torque from Wind. Predecessors have successfully been arranged in Delft, The Netherlands (2004), Lyngby, Denmark (2007) and Heraklion, Greece (2010). During the years the Torque Conference has established itself as Europe's leading scientific wind energy conference. The 2012 edition had been organized in the same tradition. More than 300 experts from academia and industry discussed the latest results and developments in fundamental and applied wind energy research, making this Science of Making Torque from Wind conference the largest one to that date. The seven keynote lectures provided the delegates with a unique overview on the state-of-the-art of science and technology. In over twenty sessions the participants discussed the most recent results in wind energy research. From numerical models to sophisticated experiments, from flow optimizations to structural designs, the numerous presentations covered a huge spectrum of ongoing scientific activities. The proceedings of the Torque 2012 combine the 110 papers that have passed the review process. We would like to thank all those who have been involved in organizing the conference and putting together these proceedings, including keynote speakers, session chairs and the enormous amount of reviewers involved. We are especially grateful to Gijs van Kuik for his untiring support. We also deeply appreciate the logistical support and technical services of the University of Oldenburg and the financial support of the State of Lower Saxony. At IOP we would like to thank Anete Ashton for her continuous encouraging support. We are looking forward to all future Torque Conferences, offering an excellent platform for the exchange of the latest and greatest scientific developments in the field of wind energy. Oldenburg, Germany, October 2014 Elke Seidel, Detlev Heinemann, Martin Kühn, Joachim Peinke and Stephan

  7. Jan Kochanowski in Königsberg

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    Bartosz Awianowicz

    2011-01-01

    Full Text Available Bartosz AwianowiczJan Kochanowski in KönigsbergScholars interested in Jan Kochanowski have paid little attention to the impact of German Humanism – as represented in Königsberg – on both the writing and the life of the poet. Indeed, Kochanowski went to Königsberg for the first time in summer or autumn 1551 andstayed until the following spring. He was there for the second time in spring or summer 1555 and remained at least until mid 1556. Especially the Polish poet’s second stay in the Prussian capital iswell documented thanks to Kochanowski’s autographed letter, written to prince Albert von Hohenzollern on April 6, 1556, and to the prince’s reply dated 15 April. Moreover, important information is recorded in the Prussian court’s expenditure accounts (Ausgabe-Bücher from 1555 and 1556. These documents give explicit evidence of the Polish poet’s links with the Ducal court. They also give implicit proof of his relations with Königsberg University and its humanists. Of all Kochanowski’s works, the most important source for his feelings towards Prussia is his Proporzec albo Hołd pruski. In it he celebrates the homage paid in 1569 to Sigismund Augustus by Albert Frederic (1553-1618, who was the son of the poet’s protector prince Albert, whom Kochanowski introduces as a model of a good monarch: a virtuous, faithful and wise prince (v. 25-36. Less known is the fact that Kochanowski’s poetry was influenced not only by Italian but also by German humanists, by the authors of handbooks of poetics and rhetoric such as Philipp Melanchthon or Joachim Camerarius, and especially by the first rector of the Albertina, Georg Sabinus (1508-1560.

  8. Germany, high-tech country

    International Nuclear Information System (INIS)

    Anon.

    1997-01-01

    The Nuclear Technology Conference organized annually by the Deutsches Atomforum (DAtF) e.V. and the Kerntechnische Gesellschaft (KTG) e.V. was held in Aachen on May 13-15, 1997. Approximately 1000 participants from seventeen countries met to exchange information with experts from industry, research, science, and politics. Unlike earlier events, this one was not disturbed by demonstrations. DAtF President Dr. Wilfried Steuer welcomed Joachim H. Witt, Chief Executive Officer of the city of Aachen, who expressed words of welcome on behalf of his city at the opening of the plenary day of the conference. Energy policy and global competition were the optics of the address by Dr. Norbert Lammert, Parliamentary Undersecretary of State with the German Federal Ministry of Economics. He advocated grasping the changes offered by expanding global markets by reforming the structures of the energy supply sector. The rank of nuclear power in European research policy was explained by Fabricio Caccia Dominioni as representative of the European Commission. The electricity utilities were represented by Dr. Dietmar Kuhnt, Chief Executive Officer of RWE AG, who spoke about the security of energy investments. A thoughtful analysis of Germany as an industrial location was presented by Professor Dr. Herbert Henzler of McKinsey and Company Inc. The President of the European Nuclear Society (ENS), Ger R. Kuepers, sketched the development of nuclear power in the Netherlands, combining national and European aspects and emphasizing, in particular, the important function of ENS. Uranium enrichment as an European project was subject of the report by Dr. Klaus Messer, Urenco Ltd. The General Manager of Tractabel Energy Engineering and Chairman of Belgatom, Guy Frederic, examined the economic viability of nuclear power, appealing to the audience to reduce capital costs by innovation without detracting from safety. (orig./DG) [de

  9. Earlier Latin Grammars as (Indirect Sources for the First Slovene Grammar Written by Adam Bohorič

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    Kozma Ahačič

    2006-07-01

    Full Text Available The paper describes some possible sources, direct and indirect, for the grammar authored by the Slovene Protestant writer Adam Bohorič. Entitled Arcticae horulae succisivae de Latinocarniolana literatura(Winter Hours of Leisure on Latin-Carniolian Grammar, it was published in 1584 as the first grammar of Slovene. Since its language is Latin, the present discussion is limited to Latin grammar works. The two direct sources of Bohorič's chapter on etymology are identified as the second or third set of editions of Melanchthon's grammar (i.e., the text as edited in 1540 by Iacobus Micyllus and slightly revised in 1550 by Joachim Camerarius and as one of the (probably bilingual editions of Donatus published before 1540 (perhaps the so-called "Torgauer Donat", of which we had access to the edition Aelii Donati Methodus ?eu Declinandi coniungandique prima elementa, pro pueris Alphabetarijs, rerum grammaticarum pror?us ignaris, diligentiori cura nunc primum concinata. Cum Epistola Phil. Mel., Vitebergae, 1542. The direct source of Bohorič's chapter on syntax is identified as the second set of editions of Melanchthon's syntax, edited in 1538 by Vitus Oertelius Winshemius. The editions of Melanchthon's Latin grammar and syntax not used by Bohorič are likewise treated in detail. Among the indirect sources, there is a brief reference to Priscian's oeuvre, with detailed descriptions reserved for the major Latin humanist grammars published before Bohorič's work: Valla, Perotti, Perger, Sulpicius, Nebrija, Manutius, Despauterius, Linacre, Alvarus, Scaliger, and Ramus.

  10. Psychological factors as risk factors for poor hip function after total hip arthroplasty

    Directory of Open Access Journals (Sweden)

    Benditz A

    2017-02-01

    Full Text Available Achim Benditz,1 Petra Jansen,2 Jan Schaible,1 Christina Roll,1 Joachim Grifka,1 Jürgen Götz1 1Department of Orthopedics, University Medical Center Regensburg, Asklepios Klinikum Bad Abbach, Bad Abbach, 2Department of Sport Science, University of Regensburg, Regensburg, Germany Abstract: Recovery after total hip arthroplasty (THA is influenced by several psychological aspects, such as depression, anxiety, resilience, and personality traits. We hypothesized that preoperative depression impedes early functional outcome after THA (primary outcome measure. Additional objectives were perioperative changes in the psychological status and their influence on perioperative outcome. This observational study analyzed depression, anxiety, resilience, and personality traits in 50 patients after primary unilateral THA. Hip functionality was measured by means of the Harris Hip Score. Depression, state anxiety, and resilience were evaluated preoperatively as well as 1 and 5 weeks postoperatively. Trait anxiety and personality traits were measured once preoperatively. Patients with low depression and anxiety levels had significantly better outcomes with respect to early hip functionality. Resilience and personality traits did not relate to hip functionality. Depression and state anxiety levels significantly decreased within the 5-week stay in the acute and rehabilitation clinic, whereas resilience remained at the same level. Our study suggests that low depression and anxiety levels are positively related to early functionality after THA. Therefore, perioperative measurements of these factors seem to be useful to provide the best support for patients with risk factors. Keywords: total hip arthroplasty, psychological factors, depression, state anxiety, trait anxiety, resilience, personality traits

  11. De la Inmaculada a la Mujer Águila del Apocalipsis, imágenes marianas novohispanas 1555-1648

    Directory of Open Access Journals (Sweden)

    Nathalie Augier de Moussac

    2013-07-01

    Full Text Available The mid XVI th century marian frescoes of the Franciscan convents of Huejotzingo, Puebla, are visual proves of the Immaculist devotion of the first missionaries. Amongst the numerous engravings from Northern Europe, which invaded New Spain via the Spanish port of Seville from the Conquest onwards, one image depicts the Virgin as the Tota Pulchra. Within the evangelisation of the New world and the intensive reproduction process it involved to impose Christian iconographies onto the American landscape, the type of the Tota pulchra was reinterpreted with an apocalyptic point of view. The Historia de los Indios de la Nueva España written by one of the first Franciscan friars who came to preach in New Spain, Toribio de Benavente, known as Motolinia, lays the principles of the Franciscan utopia derived from the millenarian theories of Joachim of Fiore, announcing the advent of the Age of the Holy Spirit and the reign of the New Eve. This particular context fostered new epiphanies around 1555, amongst which the image of the Mexican Guadalupe stands first. However it would not be until the publication, nearly a century later of Miguel Sánchez’s « Imagen de la Virgen María, Madre de Dios de Guadalupe…»(1648, whose text, largely inspired by the Augustinian exegesis identifies the Virgin of the Guadalupe with the Woman of the Revelation, that the image of the Tepeyac would acquire its canonical status of acheiropoieta and reveals itself as the living symbol of the New American Church.

  12. STIM and calcium channel complexes in cancer.

    Science.gov (United States)

    Jardin, Isaac; Rosado, Juan A

    2016-06-01

    The ion Ca(2+) is a ubiquitous second messenger that mediates a variety of cellular functions. Dysfunction of the mechanisms involved in Ca(2+) homeostasis underlies a number of pathological processes, including cancer. Store-operated Ca(2+) entry (SOCE) is a major mechanism for Ca(2+) entry modulated by the intracellular Ca(2+) stores. The Ca(2+)-selective store-operated current (ICRAC) is mediated by the endoplasmic reticulum (ER) Ca(2+) sensor STIM1 and the store-operated Ca(2+) (SOC) channel Orai1, while other non-selective cation currents (ISOC) involves the participation of members of the canonical transient receptor potential (TRPC) channel family, including TRPC1. Distinct isoforms of the key components of SOCE have been described in mammalian cells, STIM1 and 2, Orai1-3 and TRPC1-7. In cancer cells, SOCE has been reported to play an important role in cell cycle progression and proliferation, migration, metastasis and evasion of apoptosis. Changes in the expression of the key elements of SOCE and Ca(2+) homeostasis remodeling have been account to play important roles in the phenotypic changes observed in transformed cells. Despite there are differences in the expression level of the molecular components of SOCE, as well as in the relevance of the STIM, Orai and TRPC isoforms in SOCE and tumorigenesis among cancer cell types, there is a body of evidence supporting an important role for SOCE underlying the phenotypic modifications of cancer cells that propose STIM and the SOC channels as suitable candidate targets for future prognostic or therapeutic strategies. This article is part of a Special Issue entitled: Calcium and Cell Fate. Guest Editors: Jacques Haiech, Claus Heizmann, Joachim Krebs, Thierry Capiod and Olivier Mignen. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. Paleontology and Darwin's Theory of Evolution: The Subversive Role of Statistics at the End of the 19th Century.

    Science.gov (United States)

    Tamborini, Marco

    2015-11-01

    This paper examines the subversive role of statistics paleontology at the end of the 19th and the beginning of the 20th centuries. In particular, I will focus on German paleontology and its relationship with statistics. I argue that in paleontology, the quantitative method was questioned and strongly limited by the first decade of the 20th century because, as its opponents noted, when the fossil record is treated statistically, it was found to generate results openly in conflict with the Darwinian theory of evolution. Essentially, statistics questions the gradual mode of evolution and the role of natural selection. The main objections to statistics were addressed during the meetings at the Kaiserlich-Königliche Geologische Reichsanstalt in Vienna in the 1880s. After having introduced the statistical treatment of the fossil record, I will use the works of Charles Léo Lesquereux (1806-1889), Joachim Barrande (1799-1833), and Henry Shaler Williams (1847-1918) to compare the objections raised in Vienna with how the statistical treatment of the data worked in practice. Furthermore, I will discuss the criticisms of Melchior Neumayr (1845-1890), one of the leading German opponents of statistical paleontology, to show why, and to what extent, statistics were questioned in Vienna. The final part of this paper considers what paleontologists can derive from a statistical notion of data: the necessity of opening a discussion about the completeness and nature of the paleontological data. The Vienna discussion about which method paleontologists should follow offers an interesting case study in order to understand the epistemic tensions within paleontology surrounding Darwin's theory as well as the variety of non-Darwinian alternatives that emerged from the statistical treatment of the fossil record at the end of the 19th century.

  14. A well-informed ‘model of administration’ for agrarian states. Or: how not to fall into the trap of ‘nostri cation’ when comparing colonial West African States with 18th century Prussia

    Directory of Open Access Journals (Sweden)

    Hubert Treiber

    2016-01-01

    Full Text Available In a noteworthy essay entitled “The Operation Called Vergleichen (Comparison” Joachim Matthes has drawn attention to the fact that studies which claim to compare particular phenomena from one’s own culture (such as law or administration, for example with those of an alien culture do not, strictly speaking, perform a real comparison.  Instead, what takes place is (in his words a “nostrification”, that is, “an appropriation of the other in one’s own terms” or conceptual assimilation.  Even the ideal-type constructions of Max Weber seem largely to confirm this proposition.  In principle, then, it ought to be quite hard to find studies which are not exposed to the charge of nostrification.  In what follows works by Gerd Spittler are examined in some detail from this particular perspective.  In the first instance Spittler investigated the specific problems encountered by the colonial administration in West African peasant states (1919-39, before examining if this problematic could be applied to the peasant state of Prussia in the 18th century.  So, for example, he asked himself how a bureaucratic administration reliant on written documents resolved the problem of raising taxes on a body of untruly peasants who to a large extent communicated orally amongst themselves.  Since in both cases Spittler relates the typical structures of an agrarian society to typical administrative structures, he attains a level of reflection where the ‘“One” can be translated into the “Other” and vice versa’ (Matthes, and in this way he escapes the particular danger of nostrification.

  15. Nanoparticulate Quillaja saponin induces apoptosis in human leukemia cell lines with a high therapeutic index

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    Kefei Hu

    2010-01-01

    Full Text Available Kefei Hu1, Saideh Berenjian1, Rolf Larsson2, Joachim Gullbo2, Peter Nygren3, Tanja Lövgren4, Bror Morein11Department of Medical Sciences, Section of Virology, Uppsala University, Uppsala, Sweden; 2Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden; 3Department of Oncology, Radiology and Clinical Immunology, Uppsala University Hospital, Uppsala, Sweden; 4Department of Molecular Bioscience, Section for Veterinary Immunology and Virology, Swedish University of Agricultural Sciences, Uppsala, SwedenAbstract: Saponin fractions of Quillaja saponaria Molina (QS have cytotoxic activity against cancer cells in vitro, but are too toxic to be useful in the clinic. The toxic effect was abolished by converting QS fractions into stable nanoparticles through the binding of QS to cholesterol. Two fractions of QS were selected for particle formation, one with an acyl-chain (ASAP was used to form killing and growth-inhibiting (KGI particles, and the other without the acyl-chain (DSAP was used to formulate blocking and balancing effect (BBE particles. KGI showed significant growth inhibiting and cancer cell-killing activities in nine of 10 cell lines while BBE showed that on one cell line. The monoblastoid lymphoma cell line U937 was selected for analyzing the mode of action. Low concentrations of KGI (0.5 and 2 µg/mL induced irreversible exit from the cell cycle, differentiation measured by cytokine production, and eventually programmed cell death (apoptosis. Compared to normal human monocytes, the U937 cells were 30-fold more sensitive to KGI. The nontoxic BBE blocked the cell killing effect of KGI in a concentrationdependent manner. In conclusion, the formulation of QS into nanoparticles has the potential of becoming a new class of anticancer agents.Keywords: anticancer drug, Quillaja saponin, nanoparticle, apoptosis

  16. Research for the era of renewable energies: Themes 2010; Forschen fuer das Zeitalter der erneuerbaren Energien. Themen 2010

    Energy Technology Data Exchange (ETDEWEB)

    Stadermann, Gerd; Szczepanski, Petra (comps.)

    2010-12-15

    Within the jubilee meeting of the Renewable Energy Research association (Berlin, Federal Republic of Germany) from 11th to 12th October, 2010, in Berlin (Federal Republic of Germany) the following lectures were held: (1) From the foundation idea to the research association solar power (Gerd Eisenbeiss); (2) Successes affiliated - Joint research and work on the energy supply of the future (Joachim Luther); (3) Research for the era of renewable energies (Wolfgang Eberhardt); (4) Energy research package of the Federal Government: Benchmarks for the 6th Energy Research Program (Knut Kuebler); (5) Research promotion of the Federal Environment Ministry for renewable energies (Kerstin Deller); (6) Vision of a sustainable energy system 2050 (Juergen Schmid); (7) Open Invention for the demands of a new electricity age (Michael Weinhold); (8) Safeguarding the future by means of innovations in the photovoltaic industry (Ralf Luedemann); (9) Silicon wafer solar cells - New horizons (Rolf Brendel); (10) Thin film solar cells - Technology of the future? (Michael Powalla); (11) Photovoltaics - New concepts (Vladimir Dyakonov); (12) Geothermal power generation - base load electricity for the renewable energy mix 2050 (Ernst Huenges); (13) Wind energy - Challenges for the development of technology (Andreas Reuter); (14) Solar thermal power plants - Integration of electricity and fuels in a European integrated grid (Robert Pitz-Paal); (15) Efficient utilization of biomass - Residual substances, competitive uses and cascade utilization (Frank Baur); (16) Sustainable energy supply of buildings for solar and energy efficient construction (Gerd Hauser); (17) The potential of technology development for the utilization of solar power (Gerhard Stryi-Hipp); (18) Energy storage and grid management (Adreas Hauer); (19) Systems and technologies for the transition to an energy efficient town (Christina Sager); (19) Economic consequences of a 100 % supply with renewable energy as a technology

  17. How do patients with a Turkish background evaluate their medical care in Germany? An observational study in primary care

    Directory of Open Access Journals (Sweden)

    Goetz K

    2015-11-01

    Full Text Available Katja Goetz,1 Jessica Bungartz,2 Joachim Szecsenyi,1 Jost Steinhaeuser3 1Department of General Practice and Health Services Research, University of Heidelberg, Heidelberg, Germany; 2Praxis Medizin im Zentrum, München, Germany; 3Institute of Family Medicine, University Hospital Schleswig-Holstein, Lübeck, Germany Background: Patients’ evaluation of medical care is an essential dimension of quality of care and an important aspect of the feedback cycle for health care providers. The aim of this study was to document how patients with a Turkish background evaluate primary care in Germany and determine which aspects of care are associated with language abilities.Methods: The study was based on an observational design. Patients with a Turkish background from German primary care practices completed the EUROPEP (European Project on Patient Evaluation of General Practice Care questionnaire consisting of 23 items. Seventeen primary care practices were involved with either German (n=8 or Turkish (n=9 general practitioners (GPs.Results: A convenience sample of 472 patients with a Turkish background from 17 practices participated in the study (response rate 39.9%. Practices with a German GP had a lower response rate (19.6% than those with a Turkish GP (57.5%. Items evaluated the highest were “keeping data confidential” (73.4% and “quick services for urgent health problems” (69.9%. Subgroup analysis showed lower evaluation scores from patients with good or excellent German language abilities. Patients who consulted a Turkish GP had higher evaluation scores.Conclusion: The evaluation from patients with a Turkish background living in Germany with either Turkish or German GPs showed lower scores than patients in other studies in Europe using EUROPEP. However, our results had higher evaluation scores than those of Turkish patients evaluating GPs in Turkey. Therefore, different explanation models for these findings should be explored in future studies

  18. Age-based model for metacarpophalangeal joint proprioception in elderly

    Directory of Open Access Journals (Sweden)

    Rinderknecht MD

    2017-04-01

    Full Text Available Mike D Rinderknecht,1 Olivier Lambercy,1 Vanessa Raible,2 Joachim Liepert,2 Roger Gassert1 1Rehabilitation Engineering Laboratory, Department of Health Sciences and Technology, Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, Switzerland; 2Department of Neurorehabilitation, Kliniken Schmieder, Allensbach, Germany Abstract: Neurological injuries such as stroke can lead to proprioceptive impairment. For an informed diagnosis, prognosis, and treatment planning, it is essential to be able to distinguish between healthy performance and deficits following the neurological injury. Since there is some evidence that proprioception declines with age and stroke occurs predominantly in the elderly population, it is important to create a healthy reference model in this specific age group. However, most studies investigate age effects by comparing young and elderly subjects and do not provide a model within a target age range. Moreover, despite the functional relevance of the hand in activities of daily living, age-based models of distal proprioception are scarce. Here, we present a proprioception model based on the assessment of the metacarpophalangeal joint angle difference threshold in 30 healthy elderly subjects, aged 55–80 years (median: 63, interquartile range: 58–66, using a robotic tool to apply passive flexion–extension movements to the index finger. A two-alternative forced-choice paradigm combined with an adaptive algorithm to define stimulus magnitude was used. The mixed-effects model analysis revealed that aging has a significant, increasing effect on the difference threshold at the metacarpophalangeal joint, whereas other predictors (eg, tested hand or sex did not show a significant effect. The adaptive algorithm allowed reaching an average assessment duration <15 minutes, making its clinical applicability realistic. This study provides further evidence for an age-related decline in proprioception at the level of the hand

  19. Clinical relevance of persistent postoperative pain after total hip replacement – a prospective observational cohort study

    Directory of Open Access Journals (Sweden)

    Erlenwein J

    2017-09-01

    Full Text Available Joachim Erlenwein,1,* Martin Müller,1,* Deborah Falla,1,2 Michael Przemeck,3 Michael Pfingsten,1 Stefan Budde,4 Michael Quintel,1 Frank Petzke1 1Department of Anesthesiology, Pain Clinic, University Medical Center Göttingen, Georg August University of Göttingen, Göttingen, Germany; 2Centre of Precision Rehabilitation for Spinal Pain (CPR Spine, School of Sport, Exercise and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK; 3Department of Anesthesiology and Intensive Care, Annastift, Hannover, 4Department of Orthopedic Surgery, Medical School Hannover, Hannover, Germany *These authors contributed equally to this work Purpose: The development of persistent postoperative pain may occur following surgery, including total hip replacement. Yet, the prevalence may depend on the definition of persistent pain. This observational cohort study explored whether the prevalence of persistent pain after total hip replacement differs depending on the definition of persistent pain and evaluated the impact of ongoing pain on the patient’s quality of life 6 months after surgery.Patients and methods: Pre- and postoperative characteristics of 125 patients undergoing elective total hip replacement were assessed and 104 patients were available for the follow-up interview, 6 months after surgery.Results: Six months after surgery, between 26% and 58% of patients still reported hip pain – depending on the definition of persistent pain. Patients with moderate-to-severe persistent pain intensity (>3 on a numerical rating scale were more restricted in their daily life activities (Chronic Pain Grade – disability score but did not differ in reported quality of life (Short-Form 12 from those with no pain or milder pain intensity. Maximal preoperative pain intensity and body mass index were the only independent factors influencing daily function 6 months after total hip replacement.Conclusion: These

  20. Individual difficulties and resources – a qualitative analysis in patients with advanced lung cancer and their relatives

    Directory of Open Access Journals (Sweden)

    Sparla A

    2016-10-01

    Full Text Available Anika Sparla,1 Sebastian Flach-Vorgang,1 Matthias Villalobos,2 Katja Krug,1 Martina Kamradt,1 Kadiatou Coulibaly,1 Joachim Szecsenyi,1 Michael Thomas,2 Sinikka Gusset-Bährer,2 Dominik Ose1,3 1Department of General Practice and Health Services Research, Heidelberg University Hospital, 2Internistische Onkologie der Thoraxtumoren, Thoraxklinik im Universitätsklinikum Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H, Member of the German Center for Lung Research, Heidelberg, Germany; 3University of Utah, Department of Population Health Sciences, Health System Innovation and Research, Salt Lake City, UT, USA Purpose: Lung cancer is a disease with a high percentage of patients diagnosed in an advanced stage. In a situation of palliative treatment, both patients and their relatives experience diverse types of distress and burden. Little research has been done to identify the individual difficulties and resources for patients with advanced lung cancer and their relatives. Especially, standardized questionnaire-based exploration may not assess the specific distressing issues that pertain to each individual on a personal level. The purpose of this qualitative study is to explore and compare individual difficulties and resources for lung cancer patients and their relatives within the palliative care context.Methods: Data were collected by qualitative interviews. A total of 18 participants, nine patients diagnosed with advanced lung cancer (International Classification of Diseases, tenth edition, diagnosis C-34, stage IV starting or receiving palliative treatment and nine relatives, were interviewed. Data were interpreted through qualitative content analysis.Results: We identified four main categories of difficulties: communication and conflicts, home and everyday life, thinking about cancer, and treatment trajectory. In general, difficulties were related to interpersonal relationships as well as to impact of chemotherapy. Family

  1. Complexity of care and strategies of self-management in patients with colorectal cancer

    Directory of Open Access Journals (Sweden)

    Ose D

    2017-04-01

    Full Text Available Dominik Ose,1,2 Eva C Winkler,3 Sarah Berger,1 Ines Baudendistel,1 Martina Kamradt,1 Felicitas Eckrich,1 Joachim Szecsenyi1 1Department of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany; 2Department of Population Health, Health System Innovation and Research, University of Utah, Salt Lake City, UT, USA; 3Program for Ethics and Patient-oriented Care in Oncology, National Centre for Tumour Diseases, University Hospital Heidelberg, Heidelberg, Germany Purpose: Given the inherent complexity of cancer care, in which personal, social, and clinical aspects accumulate and interact over time, self-management support need to become more comprehensive. This study has the following two aims: 1 to analyze and describe the complexity of individual patient situations and 2 to analyze and describe already established self-management strategies of patients to handle this complexity.Methods: A qualitative study was conducted. Ten focus groups were performed collecting perspectives of the following three user groups: patients with colorectal cancer (n=12 and representatives from support groups (n=2, physicians (n=17, and other health care professionals (HCPs; n=16. Data were analyzed using qualitative content analysis.Results: The results showed that cancer patients are struggling with the complexity of their individual situations characterized by the 1 “complexity of disease”, 2 “complexity of care”, and 3 “complexity of treatment-related data”. To deal with these multifaceted situations, patients have established several individual strategies. These strategies are “proactive demanding” (eg, to get support and guidance or a meaningful dialog with the doctor, “proactive behavior” (eg, preparation of visits, and “proactive data management” (eg, in terms of merging treatment-related data and to disseminate these to their health care providers.Conclusion: Patients with colorectal cancer

  2. First Ph.D. Student Workshop of the Hermann von Helmholtz Association of National Research Centers (HGF) on ''Nuclear Safety Research''

    International Nuclear Information System (INIS)

    Knebel, J.U.; Sanchez Espinoza, V.H.

    2006-03-01

    The First Ph.D. Student Workshop ''Nuclear Safety Research'' of the Helmholtz Association of National Research Centers (HGF)'' was jointly organized by the Research Center Karlsruhe GmbH and the Energie Baden-Wuerttemberg AG (EnBW) from Wednesday 9th to Friday 11th March 2005. The workshop was opened with welcome greetings by Dr. Peter Fritz, Forschungszentrum Karlsruhe. Subsequently Dr. Joachim U. Knebel explained the main goals and the content of the workshop. The young scientists reported in 28 high-level presentations about their research work which covered a wide spectrum from reactor safety, partitions and transmutation, and innovative reactor systems, to safety research for nuclear waste disposal. The junior researchs showed excellent professional competence and demonstrated presentation qualities at the highest level. The successful funding of two Virtual Institutes, namely: the ''Competence in Nuclear Technologies'' and ''Functional Characteristics of Aquatic Interfaces both co-ordinated by Forschungszentrum Karlsruhe'', by the President of the Helmholtz Association Prof. Walter Kroell was the motivation for the organization of this first Ph.D. Student Workshop. Thanks to these two Virtual Institutes, the Reseach Center Karlsruhe and Juelich together with several univer-sities i.e. RWTH Aachen, Heidelberg, Karlsruhe, Muenster, and Stuttgart, have successfully financed eight Ph.D. and two post-doctoral students. Moreover, young scientists of the European Institute for Transuranium Elements (ITU) and additional seven Ph.D. Students, who are sponsored by the German nuclear industry (Framatome ANP, RWE Power, EnBW) in the frame of the Alliance Competence in on Nuclear Technology, and who are trained at Forschungszentrum Karlsruhe, actively contributed to this workshop. The EnBW-Award was handed over by Dr. Hans-Josef Zimmer, member of the board of directors of the EnBW-Kraftwerksgesellschaft, to Mrs. Ayelet Walter from the University of Stuttgart for the best

  3. Phenolic indeno[1,2-b]indoles as ABCG2-selective potent and non-toxic inhibitors stimulating basal ATPase activity

    Directory of Open Access Journals (Sweden)

    Gozzi GJ

    2015-07-01

    Full Text Available Gustavo Jabor Gozzi,1,2 Zouhair Bouaziz,3 Evelyn Winter,1,4 Nathalia Daflon-Yunes,1 Mylène Honorat,1 Nathalie Guragossian,3 Christelle Marminon,3 Glaucio Valdameri,1,2 Andre Bollacke,5 Jean Guillon,6 Noël Pinaud,7 Mathieu Marchivie,8 Silvia M Cadena,2 Joachim Jose,5 Marc Le Borgne,3 Attilio Di Pietro11Equipe Labellisée Ligue 2014, BMSSI UMR5086 CNRS/Lyon I University, IBCP, Lyon, France; 2Department of Biochemistry and Molecular Biology, Federal University of Paraná, Curitiba, Paraná, Brazil; 3Faculty of Pharmacy – ISPB, EA 4446 Biomolecules, Cancer and Chemoresistance, Health SFR of East Lyon CNRS UMS3453 - INSERM US7, University of Lyon, Lyon I University, Lyon Cedex 8, France; 4Department of Pharmaceutical Sciences, PGFAR, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil; 5Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Münster, Germany; 6ARNA Laboratory, Pharmaceutical Sciences UFR, INSERM U869, University of Bordeaux, Bordeaux Cedex, France; 7ISM – CNRS UMR 5255, University of Bordeaux Cedex, France; 8ICMCB CNRS-UPR 9048, University of Bordeaux, Pessac Cedex, FranceAbstract: Ketonic indeno[1,2-b]indole-9,10-dione derivatives, initially designed as human casein kinase II (CK2 inhibitors, were recently shown to be converted into efficient inhibitors of drug efflux by the breast cancer resistance protein ABCG2 upon suited substitutions including a N5-phenethyl on C-ring and hydrophobic groups on D-ring. A series of ten phenolic and seven p-quinonic derivatives were synthesized and screened for inhibition of both CK2 and ABCG2 activities. The best phenolic inhibitors were about threefold more potent against ABCG2 than the corresponding ketonic derivatives, and showed low cytotoxicity. They were selective for ABCG2 over both P-glycoprotein and MRP1 (multidrug resistance protein 1, whereas the ketonic derivatives also interacted with MRP1, and they additionally displayed a lower

  4. [Do prism corrections according to H.-J. Haase affect ocular prevalence?].

    Science.gov (United States)

    Schroth, V; Jaschinski, W

    2007-01-01

    For prism correction of associated phoria (at 5-6 m viewing distance), Hans-Joachim Haase developed--among other tests--the prevalence test, which consists of a central fixation target and two triangles that appear stereoscopically about 1.5 m in front of or behind the fixation target; the vertex of each triangle is directed towards the centre of the fixation target. Only when both eyes contribute equally to the perception of visual directions do the triangles appear centred (equivalence), while any perceived horizontal offset between the triangles and fixation target indicates a prevalence of one eye. Provided that monocular vision is equal in both eyes, Haase interpreted ocular prevalence as being due to a small vergence error (fixation disparity with a shift of retinal correspondence). This vergence error indicates, according to Haase, a (not yet fully corrected) heterophoria. From practical experience, Haase developed rules for transferring ocular prevalence into equivalence with prisms (MKH). If equivalence has been reached, Haase assumed that the heterophoria was fully corrected. In 19 subjects we examined whether spherical and prismatic corrections reduce ocular prevalence. The perception of the subjects was ascertained with three methods: they were asked 1. to describe their perception orally--as proposed by H.-J. Haase--, 2. to make a drawing of their perception, and 3. to align the position of the stereo images to the central fusion target with a computer-controlled device. Based on the group mean, the three methods did not reveal a consistent reduction of prevalence. Only in two individuals did the drawing and the computer-controlled alignment showed reductions of prevalence that were confirmed statistically on the individual level. However, it has to be noted that these two individuals not only received prisms but also a correction of their hyperopia and anisometropia. The prevalence of one eye is a common phenomenon in normal binocular vision (with the

  5. Agency doctorates

    International Nuclear Information System (INIS)

    1970-01-01

    Staff members of the Agency working at the Seibersdorf laboratory are continuing to achieve high academic distinction. Two more - both Austrian - have now been awarded the degree of Doctor of Agriculture. Joachim Kramer, who is 26, graduated from the Hochschule fur Bodenkultur in 1967 with the degree of Diplom-Ingenieur and then started work in the plant breeding and genetics section of the laboratory under the direction of Dr. Knut Mikaelsen. The results of the research work he carried out were accepted as the subject of a thesis for which he has now been granted his doctorate. The doctoral promotion took place on 30 June, at a ceremony attended by Dr. Andre Finkelstein, Deputy Director General for Research and Isotopes. The subject of Dr. Kramer's thesis was a comprehensive study of the mutagenic effects of fast neutrons and gamma rays, and the influence of various modifying factors such as water content, oxygen and metabolic state of seeds at the time of irradiation. This work has contributed significantly to the understanding of the mechanisms by which these two types of ionizing radiation produce mutations in seeds. The knowledge gained will be of great importance in the efficient use of ionizing radiation in practical plant breeding. Paul Wassermann, who is 33 years old, joined the Agency in 1965. He, too, graduated from the Hochschule fur Bodenkultur as Diplom-Ingenieur in agriculture, having graduated with honours previously from the agricultural secondary school at Raumberg, Austria, in 1958. Dr. Wassermann's own words may be used to explain how he came to gain his doctorate. 'In October, 1966, I completed my studies at the Hochschule,' he writes. 'I was employed at the Agency laboratories in Seibersdorf, working in the plant and soils group. Encouraged by the interesting research which was performed there, a thesis entitled 'the Fate of Nitrogen in Submerged Rice Soils' was started, which finally led to the doctor's degree in Agriculture in June this year

  6. Editor's preface

    International Nuclear Information System (INIS)

    Greiner, W.

    2001-01-01

    -energy heavy ion collisions. This symposium was meant as a token of appreciation for his life, his work and his personality by his friends and colleagues. Mike certainly would have enjoyed the fine talks, the lively discussions, the excursion to the Oelberg, and the hospitable setting at the DPG conference center. My special thanks go to the Wilhelm und Else Heraeus Stiftung for its generous support, which made this symposium possible. I want to express my gratitude to Johann Rafelski, Tucson, for his advice. Thanks are also due to Mathias Brandstetter for his assistance in organizing the conference and to Joachim Reinhardt for his help in preparing the proceedings. Finally, I acknowledge the agreeable collaboration with Istvan Lovas, editor-in-chief of Heavy Ion Physics. (author)

  7. Intravenous pamidronate versus oral and intravenous clodronate in bone metastatic breast cancer: a randomized, open-label, non-inferiority Phase III trial

    Directory of Open Access Journals (Sweden)

    von Au A

    2016-07-01

    Full Text Available Alexandra von Au,1 Eva Milloth,1 Ingo Diel,2 Stefan Stefanovic,1 Andre Hennigs,1 Markus Wallwiener,1 Joerg Heil,1 Michael Golatta,1 Joachim Rom,1 Christof Sohn,1 Andreas Schneeweiss,1 Florian Schuetz,1 Christoph Domschke1 1Breast Unit, Department of Gynecology and Obstetrics, Heidelberg University Hospital, Heidelberg, 2CGG Clinic – Centrum für ganzheitliche Gynäkologie Mannheim, Mannheim, Germany Purpose: Patients with metastasized breast cancer often suffer from discomfort caused by metastatic bone disease. Thus, osteoprotection is an important part of therapy in breast cancer metastasized to bone, and bisphosphonates (BPs are a major therapeutic option. In this study, our objectives were to compare the side effects of oral versus intravenous BP treatment and to assess their clinical effectiveness.  Patients and methods: In this prospective randomized, open-label, non-inferiority trial, we enrolled breast cancer patients with at least one bone metastasis and an Eastern Cooperative Oncology Group performance status of 0–2. Patients were randomly assigned to one of the three treatment groups: A, 60 mg pamidronate intravenously q3w; B-iv, 900 mg clodronate intravenously q3w; and B-o, 2,400 mg oral clodronate daily. Assessments were performed at baseline and every 3 months thereafter.  Results: Between 1995 and 1999, 321 patients with confirmed bone metastases from breast cancer were included in the study. At first follow-up, gastrointestinal (GI tract side effects were most common, and adverse effects on the GI tract were more frequent in the oral treatment group (P=0.002 and P<0.001, respectively. There were no statistically significant differences among the treatment cohorts for other documented side effects (skin, serum electrolytes, urinary tract, immune system, and others. No significant differences in clinical effectiveness of BP treatment, as assessed by pain score, were detected among the groups; however, pathologic fractures

  8. Bridging, switching or drug holidays – how to treat a patient who stops natalizumab?

    Directory of Open Access Journals (Sweden)

    Havla J

    2013-10-01

    Full Text Available Joachim Havla,1 Ingo Kleiter,2 Tania Kümpfel11Institute of Clinical Neuroimmunology, Medical Campus Grosshadern, Ludwig Maximilians University, Munich, 2Department of Neurology, St Josef Hospital, Ruhr University, Bochum, GermanyAbstract: Natalizumab (NAT was the first monoclonal antibody to be approved for the treatment of relapsing-remitting multiple sclerosis (RRMS. While pivotal and post-marketing studies have showed considerable and sustained efficacy of NAT in RRMS, the increasing incidence of therapy-associated progressive multifocal leukoencephalopathy (PML, a brain infection caused by the John Cunningham virus (JCV, is a risk associated with long-term therapy. The risk for therapy-associated PML is highest in so-called “triple risk” patients. Therefore, long-term NAT-treated, immunosuppressive-pretreated, and JCV antibody-positive patients often discontinue NAT therapy. However, until now, it is not known which treatment strategy should be followed after NAT cessation. Since disease activity returns to pretreatment levels, or even above, within 4–7 months from the last infusion of NAT, patients who stop NAT are at considerable risk of relapse and worsening of multiple sclerosis (MS-related disability. Several strategies have been applied to prevent the recurrence of disease activity after discontinuation of NAT. Of these, bridging with intravenous methylprednisolone, and switching to glatiramer acetate or interferon beta (IFN-beta do not seem to be effective enough. More promising results have been obtained in retrospective studies and case series with fingolimod (FTY, an alternative escalation therapy for RRMS, although some patients have showed a severe disease rebound after starting FTY treatment. The time interval between the discontinuation of NAT and the start of FTY might affect the recurrence of disease activity. Long-term data about the efficacy and safety of FTY treatment after cessation of NAT are urgently needed and

  9. Fuel cells science and engineering. Materials, processes, systems and technology. Vol. 1

    Energy Technology Data Exchange (ETDEWEB)

    Stolten, Detlef; Emonts, Bernd (eds.) [Forschungszentrum Juelich GmbH (DE). Inst. fuer Energieforschung (IEF), Brennstoffzellen (IEF-3)

    2012-07-01

    The first volume is divided in four parts and 22 chapters. It is structured as follows: PART I: Technology. Chapter 1: Technical Advancement of Fuel-Cell Research and Development (Dr. Bernd Emonts, Ludger Blum, Thomas Grube, Werner Lehnert, Juergen Mergel, Martin Mueller and Ralf Peters); 2: Single-Chamber Fuel Cells (Teko W. Napporn and Melanie Kuhn); 3: Technology and Applications of Molten Carbonate Fuel Cells (Barbara Bosio, Elisabetta Arato and Paolo Greppi); 4: Alkaline Fuel Cells (Erich Guelzow); 5: Micro Fuel Cells (Ulf Groos and Dietmar Gerteisen); 6: Principles and Technology of Microbial Fuel Cells (Jan B. A. Arends, Joachim Desloover, Sebastia Puig and Willy Verstraete); 7: Micro-Reactors for Fuel Processing (Gunther Kolb); 8: Regenerative Fuel Cells (Martin Mueller). PART II: Materials and Production Processes. Chapter 9: Advances in Solid Oxide Fuel Cell Development between 1995 and 2010 at Forschungszentrum Juelich GmbH, Germany (Vincent Haanappel); 10: Solid Oxide Fuel Cell Electrode Fabrication by Infiltration (Evren Gunen); 11: Sealing Technology for Solid Oxide Fuel Cells (K. Scott Weil); 12: Phosphoric Acid, an Electrolyte for Fuel Cells - Temperature and Composition Dependence of Vapor Pressure and Proton Conductivity (Carsten Korte); 13: Materials and Coatings for Metallic Bipolar Plates in Polymer Electrolyte Membrane Fuel Cells (Heli Wang and John A. Turner); 14: Nanostructured Materials for Fuel Cells (John F. Elter); 15: Catalysis in Low-Temperature Fuel Cells - An Overview (Sabine Schimpf and Michael Bron). PART III: Analytics and Diagnostics. Chapter 16: Impedance Spectroscopy for High-Temperature Fuel Cells (Ellen Ivers-Tiffee, Andre Leonide, Helge Schichlein, Volker Sonn and Andre Weber); 17: Post-Test Characterization of Solid Oxide Fuel-Cell Stacks (Norbert H. Menzler and Peter Batfalsky); 18: In Situ Imaging at Large-Scale Facilities (Christian Toetzke, Ingo Manke and Werner Lehnert); 19: Analytics of Physical Properties of Low

  10. Factors associated with medication information in diabetes care: differences in perceptions between patients and health care professionals

    Directory of Open Access Journals (Sweden)

    Längst G

    2015-10-01

    Full Text Available Gerda Längst,1 Hanna Marita Seidling,2,3 Marion Stützle,2,3 Dominik Ose,1 Ines Baudendistel,1 Joachim Szecsenyi,1 Michel Wensing,1,4 Cornelia Mahler1 1Department of General Practice and Health Services Research, University Hospital of Heidelberg, Heidelberg, Germany; 2Cooperation Unit Clinical Pharmacy, University of Heidelberg, Heidelberg, Germany; 3Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Heidelberg, Germany; 4Radboud University Nijmegen Medical Centre, Scientific Institute for Quality of Healthcare, Nijmegen, the Netherlands Purpose: This qualitative study in patients with type 2 diabetes and health care professionals (HCPs aimed to investigate which factors they perceive to enhance or impede medication information provision in primary care. Similarities and differences in perspectives were explored.Methods: Eight semistructured focus groups were conducted, four with type 2 diabetes patients (n=25 and four with both general practitioners (n=13 and health care assistants (n=10. Sessions were audio and video recorded, transcribed verbatim, and subjected to computer-aided qualitative content analysis.Results: Diabetes patients and HCPs broadly highlighted similar factors as enablers for satisfactory medication information delivery. Perceptions substantially differed regarding impeding factors. Both patients and HCPs perceived it to be essential to deliver tailored information, to have a trustful and continuous patient–provider relationship, to regularly reconcile medications, and to provide tools for medication management. However, substantial differences in perceptions related to impeding factors included the causes of inadequate information, the detail required for risk-related information, and barriers to medication reconciliation. Medication self-management was a prevalent topic among patients, whereas HCPs’ focus was on fulfilling therapy and medication management responsibilities

  11. PREFACE: XXVIII International Conference on Photonic, Electronic and Atomic Collisions (ICPEAC 2013)

    Science.gov (United States)

    Xiao, Guoqing; Cai, Xiaohong; Ding, Dajun; Ma, Xinwen; Zhao, Yongtao

    2014-04-01

    The 28th International Conference on Photonic, Electronic and Atomic Collisions (XXVIII ICPEAC) was held by the Institute of Modern Physics, Chinese Academy of Sciences (IMP) on 24-30 July, 2013 in Lanzhou, China. The 444 conference participants came from 37 countries and/or regions. Five plenary lectures, more than 80 progress reports and special reports had been arranged according to the decision of the ICPEAC International General Committee. Meanwhile, more than 650 abstracts were selected as poster presentations. Before the conference, three highly distinguished scientists, Professor Joachim Burgdöorfer, Professor Hossein Sadeghpour and Professor Yasunori Yamazaki, presented tutorial lectures with the support of the IMP Branch of Youth Innovation Promotion Association, CAS (IMP-YIPA). During the conference, Professor Jianwei Pan from University of Sciences and Technology in China presented an enlightening public lecture on quantum communication. Furthermore, 2013 IUPAP Young Scientist Prize was awarded to Dr T Jahnke from Johann Wolfgang Goethe University of Germany. The Sheldon Datz Prize for an Outstanding Young Scientist Attending ICPEAC was awarded to Dr Diogo Almeida from University of Fribourg of Switzerland. As a biannual academic conference, ICPEAC is one of the most important international conferences on atomic and molecular physics. The topic of the conference covers the recent progresses in photonic, electronic, atomic, ionic, molecular, cluster collisions with matter. With a history back to 1958, ICPEAC came to China for the very first time. IMP has been preparing the conference six years before, ever since the ICPEAC International General Committee made the decision to hold the XXVIII ICPEAC in Lanzhou. This proceedings includes the papers of the two plenary lectures, 40 progress reports, 17 special reports and 337 posters, which were reviewed and revised according to the comments of the referees. The Local Organizing Committee would like to

  12. The short live of the climate lie; Die kurzen Beine der Klimaluege

    Energy Technology Data Exchange (ETDEWEB)

    Thuss, Holger; Courtillot, Vincent; Shaviv, Nir (and others)

    2011-07-01

    A worldwide network of fear lobby claims with missionary enthusiasm: Climate change means the end of the world. But the facts are quite different. The DVDs under consideration are required by anyone who do not want to trusts blindly the statements of politicians, environmental groups and lobbyists. After all, the climate paranoia specifically benefits some stakeholders as an ideal knockout argument in order to push through more tax increases or to gain power and influence. The most renowned experts and scientists of the 'climate skeptics' met at the 3rd International Power and Climate Conference of the European Institute for Climate and Energy (EIKE) at 3rd to 4th December, 2010 in Berlin (Federal Republic of Germany) in order to keep you up to date of their unprejudiced research on the issue of the man-made global warming. Within this meeting the following lectures were held: (1) Holger Thuss: Why is climate still an issue (Holger Thuss); (2) Scientific results by consensus? (vincent Courtillot); (3) New insights into the solar impact on climate and its importance for the understanding of climate change (Nir Shaviv); (4) Threats from climate change - adaptation is the solution (Bob Carter); (5) The lobby of the renewable energy industry (Guenter Ederer); (6) Climate 'protection' as an instrument of geostrategic politics (Emmanuel Martin); (7) What is the importance of Climategate for science? (Terence Kealey); (8) Live from Cancun - video conference from the UN Climate Change Conference in Cancun (Roy Spencer, Lord Christopher Monckton); (9) Climate, water, carbon dioxide and the sun (Jan Veizer); (10) Man vs. Nature - Who emits more CO{sub 2}? (Ian Plimer); (11) Climate change between models, statistics and substitute religion (Werner Kirstein); (12) Persistence in temperature series shows the impact of the sun on our climate (Horst-Joachim Luedecke); (13) Worldwide long-term data show the majority of thermometer is not heated (Friedrich

  13. Calcium remodeling in colorectal cancer.

    Science.gov (United States)

    Villalobos, Carlos; Sobradillo, Diego; Hernández-Morales, Miriam; Núñez, Lucía

    2017-06-01

    salicylate and other NSAIDs inhibits tumor cell growth acting on SOCE, 3) evidences on the remodeling of intracellular Ca 2+ in cancer with a particular emphasis in SOCE, 4) the remodeling of SOCE and Ca 2+ store content in CRC and, finally, 5) the molecular basis of Ca 2+ remodeling in CRC. This article is part of a Special Issue entitled: ECS Meeting edited by Claus Heizmann, Joachim Krebs and Jacques Haiech. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. The effect of intravitreal bevacizumab (Avastin® on ocular pulse amplitude in neovascular age-related macular degeneration

    Directory of Open Access Journals (Sweden)

    Ehud Rechtman

    2011-01-01

    Full Text Available Ehud Rechtman1, Ingeborg Stalmans2, Joseph Glovinsky1, Christophe Breusegem2, Joseph Moisseiev1, Joachim Van Calster2, Alon Harris31Goldschleger Eye Institute, Sheba Medical Center, Ramat Gan, Israel; 2Department of Ophthalmology, University Hospitals Leuven, Leuven, Belgium; 3Department of Ophthalmology, Indiana University, Indianapolis, IN, USAPurpose: To evaluate the effect of intravitreal (IVT bevacizumab in neovascular age-related macular degeneration (AMD on global choroidal hemodynamics, as measured by ocular pulse amplitude (OPA.Methods: This was a two-center prospective study (Sheba Medical Center, Israel, and University Hospitals Leuven, Belgium. AMD patients who required IVT bevacizumab (1.25 mg/0.05 mL; first or repeated were examined three times: at days 0 (prior to injection, 7 (±3, and 28 (±7 postinjection. At each visit, OPAs of both eyes were measured using the Pascal dynamic contour tonometer (DCT. A paired t-test between preoperative and postoperative OPA was conducted. Pearson correlation was used to evaluate the influence of various measured parameters on DCT–OPA.Results: A total of 38 neovascular AMD patients were recruited, and 30 patients were included in the final analysis (18 females and 12 males; age 78.8 ± 5.82 years [mean ± standard deviation]. A good correlation was found throughout the study between the DCT–intraocular pressure (IOP and Goldmann IOP and between DCT–IOP and DCT–OPA. No change in OPA of bevacizumab-treated eyes was found between the visits (2.24 ± 0.73, 2.2 ± 0.86, and 2.23 ± 0.73 mm Hg at visits 1, 2, and 3, respectively; paired t-test: P = 0.77 between visits 1 and 2, P = 0.98 between visits 1 and 3. No correlations were found between DCT–OPA and age, heart rate, systemic blood pressure, axial length, keratometry readings, and central corneal thickness.Conclusions: OPA, an indirect measure of global choroidal hemodynamics, remains unchanged following IVT off-label bevacizumab. This

  15. Handheld single photon emission computed tomography (handheld SPECT) navigated video-assisted thoracoscopic surgery of computer tomography-guided radioactively marked pulmonary lesions.

    Science.gov (United States)

    Müller, Joachim; Putora, Paul Martin; Schneider, Tino; Zeisel, Christoph; Brutsche, Martin; Baty, Florent; Markus, Alexander; Kick, Jochen

    2016-09-01

    radioactive marking was unsuccessful because the radioactivity spread into the pleural space. In our series of 10 patients, it was demonstrated that using handheld SPECT in conjunction with VATS to remove radioactively marked pulmonary nodules is feasible. The combination of proven surgical techniques with a novel localization device (handheld SPECT) allowed successful VATS excision of pulmonary nodules which, due to their localization and small size, would typically have required thoracotomy. ClinicalTrials.gov, NCT02050724, Public 01/29/214, Joachim Müller. © The Author 2016. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

  16. La investigación en el Área de Pintura Flamenca y Escuelas del Norte del Museo del Prado

    Directory of Open Access Journals (Sweden)

    Vergara Sharp, Alejandro

    2006-02-01

    Full Text Available This article describes different research projects undertaken in the Area of Flemish and Northern European Painting at the Prado museum. One was devoted to the Adoration of the Magi, a painting by Rubens which has offers unusual insight into his creative personality. A second project was devoted to the study of a series of tapestries designed by Rubens, which show episodes of the life of Achilles. In this case the project was the result of a collaboration with the Boijmans Van Beuningen Museum in Rotterdam. At present, the Prado is conducting research into the art of Joachim Patinir, an landscape artist active in Antwerp in the early sixteenth century. In all three cases the Prado is responding to its responsibility to study its own collections.El Museo Nacional del Prado posee una de las colecciones de pintura flamenca de los siglos XV, XVI y XVII de mayor calidad y tamaño que existen, y también es depositario de obras de arte de gran importancia de origen alemán (entre ellas varios cuadros de Durero, holandés (Rembrandt y de otros países cuyo arte se engloba dentro del Área de Conservación de Pintura Flamenca y Escuelas del Norte del museo. Al margen de conservar estas obras y de mostrar al público el mayor número de ellas en condiciones idóneas, también dedicamos una parte importante de nuestra actividad a la investigación. La calidad superlativa de la colección del Prado nos confiere una gran responsabilidad: tenemos la obligación de ser líderes, a nivel mundial, en el estudio de las cuestiones que plantea la historia del arte respecto de los artistas y los cuadros de la colección. En las siguientes páginas se explican tres proyectos de investigación desarrollados por el Área de Pintura Flamenca recientemente, que muestran el abanico de proyectos los que trabajamos en el Prado, los criterios que nos guían a la hora de seleccionarlos, y la forma en que se desarrollan.

  17. II. Monographic SectionPolitics and devotion around the memory of the Passion in the Western world (Middle Ages - Modern Times

    Directory of Open Access Journals (Sweden)

    Laura Gaffuri (a cura di

    2016-06-01

    Full Text Available The seven texts in this folder invite the scholar to study the phenomena of producing and reproducing objects and places connected to the memory of the Passion in the Middle Ages and Early Modern Times. Its focus is on illustrating the fertile convergence of two approaches, one focusing on the religious sensibility, the other scrutinizing above all the uses and political meanings of the devotional processes, as Ludovic Viallet points out in his introduction by emphasizing the concepts of both “localization” and “collective imagination”. Three articles are then dedicated to representations or reproductions supporting a devotion or a spiritual pilgrimage in the late Middle Ages: Hans-Joachim Schmidt analyzes several maps and tales which made the Holy Places of Jerusalem accessible for those who couldn’t make the trip to them; Peter Kurmann shows that the Holy Sepulcher, which has been near the Constance cathedral since the tenth century, was renovated shortly after the middle of the thirteenth century to be adapted to its new role as a Eucharistic receptacle, as it was the destination of a weekly procession in which the Holy Eucharist was venerated; finally, Elsa Karsallah examines the monumental “Entombments” which appeared in France in the 1420s. Paolo Cozzo then shows that in the Early Modern Savoy Dukedom the worship of the Shroud gave rise to a system of copies brought into contact with the original and distributed in the European courts to strengthen the identity and prestige of the dynasty, as did the promotion of important Marian shrines. Furthermore, in the fifteenth century the dukes of Savoy reproduced a more “political” paradigm, that of the Sainte-Chapelle which was forged in Paris two centuries earlier: Laura Gaffuri fully revises the folder of that Savoy foundation. What does the notion of replication ultimately means? asks Catherine Vincent in the conclusion, highlighting in particular the paradox inherent to the

  18. Reinforcement course 2013. Challenges at the operation end of nuclear power plants

    International Nuclear Information System (INIS)

    Rey, Matthias

    2014-01-01

    as Part of the Dismantling Planning' by Ben Volmert, Beat Bitterli, Erwin Neukaeter and Manuel Pantelias; 'Strategies of dismantling - Technical Feasibility and Nuclear Safety' by Hans Genthner and Erwin Prechtl, 'Logistic Supply Chains at the Dismantling Process of Nuclear Power Plants' by Karl Wasinger and Claudius Grasnick, 'Decontamination in Swiss Nuclear Industry - An Overview Based on Experiences of Zwilag' by Uwe Kasemayer, Donat Gubler, Stefan Haefeli, Christian Hoesli, Hans-Joachim Lau and Andreas Wegmueller as well as 'Dismantling Technics and Methods from the Scientific Perspective' by Sascha Gentes. (orig.)

  19. Efficacy and safety of an oral contraceptive containing ethinylestradiol 20 µg/drospirenone 3 mg (24/4 regimen in three indications in the People's Republic of China: a comparison with international studies

    Directory of Open Access Journals (Sweden)

    Marr J

    2015-07-01

    Full Text Available Joachim Marr,1 Zirong Huang,2 Baoxi Wang,3 Hongyan Zhang,4 Katrin Roth1 1Bayer Pharma AG, Berlin, Germany; 2Obstetrics and Gynecology Hospital of Fudan University, Shanghai, 3Institute of Dermatology, Chinese Academy of Medical Sciences, Nanjing, Jiangsu, 4Peking University Sixth Hospital, Peking University Institute of Mental Health, Ministry of Health (Peking University, Beijing, People's Republic of China Abstract: While combined oral contraceptives are a popular choice in developed Western countries, they are used by only 1% of women who are married or in a relationship in the People's Republic of China. The purpose of this review is to describe the efficacy and safety of the combined oral contraceptive containing ethinylestradiol (EE 20 µg/drospirenone 3 mg taken in a 24/4 regimen (YAZ®; Bayer HealthCare Pharmaceuticals, Berlin, Germany by Chinese women and to compare these results with those in women assessed in the international studies. Studies of EE 20 µg/drospirenone 3 mg in three different indications (contraception, acne, and premenstrual dysphoric disorder [PMDD] have been conducted in Chinese women. The results of these three studies indicate that the EE 20 µg/drospirenone 3 mg combined oral contraceptive is a good long-term contraceptive option in Chinese women, providing 99% contraceptive protection over the observed 1-year treatment period, and additionally had a favorable effect on moderate acne vulgaris and relieved the symptoms of PMDD. The contraceptive efficacy, improvement in acne, and relief from PMDD symptoms observed in these studies did not differ from the effects observed in other international studies of EE 20 µg/drospirenone 3 mg, indicating that EE 20 µg/drospirenone 3 mg is as effective in Chinese women as in other ethnicities. Further, EE 20 µg/drospirenone 3 mg demonstrated a similar safety and tolerability profile in women enrolled in the Chinese and international trials, with no unexpected adverse

  20. Safety and tolerability of flexible dosages of prolonged-release OROS methylphenidate in adults with attention-deficit/hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Jan K Buitelaar

    2009-08-01

    Full Text Available Jan K Buitelaar1, J Antoni Ramos-Quiroga2, Miguel Casas2, J J Sandra Kooij3, Asko Niemelä4, Eric Konofal5, Joachim Dejonckheere6, Bradford H Challis7, Rossella Medori81Department of Psychiatry, University Medical Center, St. Radboud and Karakter Child and Adolescent Psychiatry University Center, Nijmegen, The Netherlands; 2Department of Psychiatry, Hospital Universitari Vall d’Hebron and Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain; 3PsyQ, Psycho-Medical Programs, Program Adult ADHD, Den Haag, The Netherlands; 4Oulu University Hospital, Department of Psychiatry, Oulu, Finland; 5Groupe Hospitalier Pitie-Salpetriere, Paris, France; 6SGS Life Sciences, Mechelen, Belgium; 7Johnson & Johnson Pharmaceutical Research and Development, Titusville, NJ, USA; 8Janssen-Cilag EMEA, Neuss, GermanyAbstract: The osmotic release oral system (OROS methylphenidate formulation is a prolonged-release medication for the treatment of attention-deficit/hyperactivity disorder (ADHD in children, adolescents, and adults. We conducted a seven-week open-label extension of a double-blind study to assess the safety and tolerability of OROS methylphenidate in a flexible dose regimen (18–90 mg daily for the treatment of adults diagnosed with ADHD (N = 370. Medication was adjusted to optimize efficacy and tolerability for each patient. Adverse events, vital signs, and laboratory parameters were assessed. Most patients (337; 91% completed the seven-week treatment and the final dispensed dose was 18 mg (8%, 36 mg (29%, 54 mg (34%, 72 mg (20%, or 90 mg (9%. Adverse events were reported in 253 (68% patients and most were mild or moderate in severity; most frequently reported included headache (17%, decreased appetite (13%, and insomnia (11%. Adverse events were rarely serious (<1%; 2/370. Small mean increases in systolic and diastolic blood pressure (both 2.4 mmHg and pulse (3.2 bpm were observed. Body weight decreased

  1. Can consistent benchmarking within a standardized pain management concept decrease postoperative pain after total hip arthroplasty? A prospective cohort study including 367 patients

    Directory of Open Access Journals (Sweden)

    Benditz A

    2016-12-01

    Full Text Available Achim Benditz,1 Felix Greimel,1 Patrick Auer,2 Florian Zeman,3 Antje Göttermann,4 Joachim Grifka,1 Winfried Meissner,4 Frederik von Kunow1 1Department of Orthopedics, University Medical Center Regensburg, 2Clinic for anesthesia, Asklepios Klinikum Bad Abbach, Bad Abbach, 3Centre for Clinical Studies, University Medical Center Regensburg, Regensburg, 4Department of Anesthesiology and Intensive Care, Jena University Hospital, Jena, Germany Background: The number of total hip replacement surgeries has steadily increased over recent years. Reduction in postoperative pain increases patient satisfaction and enables better mobilization. Thus, pain management needs to be continuously improved. Problems are often caused not only by medical issues but also by organization and hospital structure. The present study shows how the quality of pain management can be increased by implementing a standardized pain concept and simple, consistent, benchmarking.Methods: All patients included in the study had undergone total hip arthroplasty (THA. Outcome parameters were analyzed 24 hours after surgery by means of the questionnaires from the German-wide project “Quality Improvement in Postoperative Pain Management” (QUIPS. A pain nurse interviewed patients and continuously assessed outcome quality parameters. A multidisciplinary team of anesthetists, orthopedic surgeons, and nurses implemented a regular procedure of data analysis and internal benchmarking. The health care team was informed of any results, and suggested improvements. Every staff member involved in pain management participated in educational lessons, and a special pain nurse was trained in each ward.Results: From 2014 to 2015, 367 patients were included. The mean maximal pain score 24 hours after surgery was 4.0 (±3.0 on an 11-point numeric rating scale, and patient satisfaction was 9.0 (±1.2. Over time, the maximum pain score decreased (mean 3.0, ±2.0, whereas patient satisfaction

  2. GSI DARMSTADT: 25 years

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    Full text: On May 12, Hans J. Specht, Scientific Director of the Geseilschaft fur Schwerionenforschung (GSI), welcomed an audience of more than 500 to celebrate the 25th anniversary of the Darmstadt heavy ion research Laboratory. Warm greetings and best wishes from Jürgen Ruttgers, Federal Minister for Education, Science, Research and Technology were presented by Hartmut Grubei, Chairman of the GSI Board. The Hessian Minister for Science and Art, Christine Hohmann-Dennhardt, pointed out that the promotion of various fields of research cannot be judged only by the expected return for everyday life. Joachim Treusch, the Chairman of the Association of National Research Centres, went further by stating that basic research, driven by curiosity and not aiming at short term applications, is a necessity. Darmstadt Mayor Peter Benz expressed his pride in having such a prestigious Laboratory in the city and looked forward to a new element named after it. CERN Director General Chris Llewellyn Smith underlined the growing importance of international and inter-regional scientific collaboration and paid tribute to the role of German physicists in general and GSI in particular in CERN's work. GSI is a major partner in the international lead ion programme at CERN which came into operation last year, a scientific and technological success which provides a useful role model for future international partnerships. After pointing to interesting parallels between the two Laboratories - both basing new projects on existing facilities, and both serving large user communities - he thanked GSI for its valuable contributions to CERN. Highlights from the 25 years of GSI were summarized in a talk by Dirk Schwalm, Managing Director of the Max Planck Institute for Nuclear Physics in Heidelberg. Among other points he presented the unique accelerator facility and the discovery of the five heaviest elements. He stated that many dreams from the founding period of GSI had become a reality, and

  3. CTI capacity building seminar for CEE/FSU countries. Climate technology and energy efficiency. Challenges and changes for climate technology. Seminar proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Tempel, Sybille; Moench, Harald (eds.); Mez, Lutz; Krug, Michael (comps.) [Free Univ. Berlin (DE). Environmental Policy Research Centre (FFU)

    2005-01-15

    Within the CTI Capacity Building Seminar for CEE/FSU Countries at 20th to 24th September, 2003 in Tutzing (Federal Republic of Germany) the following lectures were held: (1) Excursion to fuel cell pilot project (Peter Fleischmann); (2) How to construct a climate change program - some basics (Franzjosef Schafhausen); (3) The EU emissions trading directive (Felix Matthes); (4) Emissions trading - The implementation of the EU-Directive in Germany (Franzjosef Schafhausen); (5) Emissions trading from a buyer's perspective (Albrecht von Ruffer); (6) Emissions trading from a seller's perspective: Czech Republic (Toma Chmelik); (7) Discussant notes: Emissions trading (Sonja Butzengeiger); (8) Carbon finance and the world bank: Chances, experiences, lessons learned (Charlotte Streck); (9) Joint implementation: Relationship to and compatibility with the emission trading scheme (Franzjosef Schafhausen); (10) Clean development mechanism in Central Asia (Liliya Zavyalova); (11) Creating a national CDM system in Georgia (Paata Janelidze); (12) Experiences from the certification of JI/CDM projects (Michael Rumberg); (13) Discussant notes Session JI and CDM (Tiit Kallaste); (14) The EU Directive on electricity from renewable energy sources 2001/77/EC (Volkmar Lauber); (15) Amending the Renewable Energy Source Act (Thorsten Mueller); (16) The new renewables support scheme in te Czech Republic (Martin Busik); (17) Replacing nuclear energy by renewables. The case of Lithunia (Kestutis Buinevicius); (18) Renewables in the New Energy Acts of Estonia (Villu Vares); (19) Discussant notes: Session incentive schemes for renewables (Hans-Joachim Ziesing); (20) Bankable energy efficiency projects - How to get energy efficiency investment financed (Petra Opitz); (21) Clear contract - clearinghouse for contracting (Ralf Goldmann); (22) CHP as an important element of a sustainable energy use in Germany (Juergen Landrebe); (23) The European CHP Directive - a step towards the smarter

  4. The Ultraviolet Albedo of Ganymede

    Science.gov (United States)

    McGrath, Melissa; Hendrix, A.

    2013-10-01

    A large set of ultraviolet images of Ganymede have been acquired with the Hubble Space Telescope over the last 15 years. These images have been used almost exclusively to study Ganymede’s stunning auroral emissions (Feldman et al. 2000; Eviatar et al. 2001; McGrath et al. 2004; Saur et al. 2011; McGrath et al. 2013), and even the most basic information about Ganymede’s UV albedo has yet to be gleaned from these data. We will present a first-cut analysis of both disk-averaged and spatially-resolved UV albedos of Ganymede, with focus on the spatially-resolved Lyman-alpha albedo, which has never been considered previously for this satellite. Ganymede's visibly bright regions are known to be rich in water ice, while the visibly dark regions seem to be more carbonaceous (Carlson et al., 1996). At Lyman-alpha, these two species should also have very different albedo values. References Carlson, R. and 39 co-authors, Near-infrared spectroscopy and spectral mapping of Jupiter and the Galilean satellites: Results from Galileo’s initial orbit, Science, 274, 385-388, 1996. Eviatar, A., D. F. Strobel, B. C. Wolven, P. D. Feldman, M. A. McGrath, and D. J. Williams, Excitation of the Ganymede ultraviolet aurora, Astrophys. J, 555, 1013-1019, 2001. Feldman, P. D., M. A. McGrath, D. F. Strobel, H. W. Moos, K. D. Retherford, and B. C. Wolven, HST/STIS imaging of ultraviolet aurora on Ganymede, Astrophys. J, 535, 1085-1090, 2000. McGrath M. A., Lellouch E., Strobel D. F., Feldman P. D., Johnson R. E., Satellite Atmospheres, Chapter 19 in Jupiter: The Planet, Satellites and Magnetosphere, ed. F. Bagenal, T. Dowling, W. McKinnon, Cambridge University Press, 2004. McGrath M. A., Jia, Xianzhe; Retherford, Kurt; Feldman, Paul D.; Strobel, Darrell F.; Saur, Joachim, Aurora on Ganymede, J. Geophys. Res., doi: 10.1002/jgra.50122, 2013. Saur, J., S. Duling, S., L. Roth, P. D. Feldman, D. F. Strobel, K. D. Retherford, M. A. McGrath, A. Wennmacher, American Geophysical Union, Fall Meeting

  5. IV National Conference on Dermatocosmetic Sciences - Proceedings

    Directory of Open Access Journals (Sweden)

    Escola de Ciências e Tecnologias da Saúde (ECTS da Univ Lusófona de Humanidades e Tecnologias

    2013-06-01

    novo Regulamento de Cosméticos – Ana Maria Couras, The industry "in Portuguese" | Cosmética em Português – Rui Vilas Boas Education for Health | Educação para a Saúde – Leonor Girão Effect of antioxidants in sunscreens| Fotoestabilidade de filtros solares: estudo do efeito de antioxidantes – Sara Afonso keynote lecture | Conferência Magistral Photoaging, skin cancers and sunscreens: what's Hot and what's Not? – Toni Ionescu 2nd Session | Sessão 2 State of the Art I | O estado da arte I Moderator | Moderador- Joachim Fluhr Preparations containing dermocosmetic geomaterials from the island of São Miguel | Preparações dermocosméticas contendo geomateriais da Ilha de São Miguel - Arquipélago dos Açores – Marilene Estanqueiro The possibility of applicability of the extracts of the Ginja in the wellness of the human skin | Estudo do potencial de aplicabilidade dos extractos de Ginja na promoção da saúde e bem-estar cutâneos – Elisabete Mauricio Topical formulations: from concept to market | Formulações tópicas: do conceito ao mercado – Sara Raposo, FFUL 3rd Session | Sessão 3 State of the Art II | O Estado da Arte II Moderator | Moderador- Isabel Almeida, Cutaneous impact of dietary consumption of water | Impacto cutâneo do consumo dietário de água – Lidia Palma Cosmetics in aesthetics recovery | Papel da Cosmética na recuperação estética – Vitor Figueiredo Novel scientific approaches to the discovery of new actives – Liliana Vilas Technology and innovation/ safety in cosmetics development | A tecnologia dos cosméticos: desenvolvimento e inovação/ segurança – Joana Marto, FFUL keynote lecture | Conferência Magistral What's new with the epidermal barrier? – Joachim Fluhr

  6. Photovoltaic solar energy. Proceedings; Photovoltaische Solarenergie. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    Within the 21st symposium 'Photovoltaic Solar Energy' of the Ostbayerisches Technologie-Transfer-Institut e.V. (Regensburg, Federal Republic of Germany) at Banz Monastery (Bad Staffelstein, Federal Republic of Germany) between 8th and 10th March, 2006, the following lessons were held: (1) Basic conditions for a market support programme in the European context (EEG) (Winfried Hoffmann); (2) Actual developments in the German market of photovoltaics (Gerhard Stryi-Hipp); (3) Become a part of the global economic survey of Task 2 ''PV cost over time'' (Thomas Nordmann); (4) The market of photovoltaic will be a European market in the future (Murray Cameron); (5) Development and state of the art of the photovoltaic industry in the Peoples Republic of China (Frank Haugwitz); (6) Silicon for the photovoltaic industry (Karl Hesse); (7) Cell technology: Impulses for a cost effective photovoltaic with valuable silicon (Rolf Brendel); (8) Thin-film solar modules for the photovoltaic - state of the art and industrial perspectives (Michael Powalla); (9) Modules - bottleneck and flood of orders: How to act an installer? (Helmut Godard); (10) Photovoltaic open-field systems - Actual experiences and conflict lines (Ole Langniss); (11) Comparison of actual and future trends of Balance-of-System costs for large scale ground based PV systems with crystalline and thin-film modules (Manfred Baechler); (12) Financing PX projects from a Bank perspective (Joachim Treder); (13) Criteria of quality for solar fonds - Criteria of evaluation for capital investors and self-commitment for emission houses (Ulla Meixner); (14) Analysis of the distribution pathways for photovoltaic plants from the manufacturer to the final customer considering the decreasing demand and increasing prices (Michael Forst); (15) Solar power 2005 - Evaluation of real operational data of 1,000 plants in Germany (Gerd Heilscher); (16) Improvement of PV-inverter efficiency - targets, pathways

  7. Tõlkepärl eesti ilukirjanduse algusaegadest – esimene eestikeelne robinsonaad / A Translation Gem from the Beginnings of Estonian Literature - the First Robinsonade

    Directory of Open Access Journals (Sweden)

    Ave Mattheus

    2015-06-01

    Full Text Available Teesid: Artiklis uuritakse Eesti Kirjandusmuuseumis asuvat mahukat, ligi 800 lk tõlkekäsikirja „Norem Robinson“, mida võib pidada esimeseks eesti kirjanduse täiemahuliseks robinsonaadiks. Selle valmistas Pärnu koolmeister Heinrich Gottlieb Lorenzsonn saksa pedagoogi ja koolikirjaniku Joachim Heinrich Campe menukast noorsooromaanist „Robinson der Jüngere“ (1779–1780. Tõlge valmis 1822.–1823. aastal, kuid jõudis trükki alles 1842. aastal tugevasti kärbitud ja mugandatud kujul. Toetudes deskriptiivse tõlkeuurimuse analüüsikategooriatele, vaadeldakse artiklis, millised tegurid tõlkeprotsessi suunasid ja milline oli kultuuriruum, kuhu tõlge omal ajal paigutus. SU M M A R Y This article discusses a voluminous manuscript translation of almost 800 pages entitled Norem Robinson (Engl. Robinson the Younger, from the collections of the Estonian Literary Museum. This manuscript can be considered as the first complete Robinsonade in Estonian literature. Its author is a schoolteacher from Pärnu, Heinrich Gottlieb Lorenzsonn (1803–1847, who translated it from the youth novel Robinson der Jüngere(1779–1780, Engl. Robinson the Younger, a bestseller by the educator, writer and a major representative of German Enlightenment, Heinrich Joachim Campe. Lorenzsonn’s translation was completed in 1822–1823, but not printed until 1842 in a strongly adapted version titled Norema Robinsoni ello ja juhtumised ühhe tühja sare peäl (Engl. The Life and Adventures of Robinson the Younger on a deserted island. The print version of the Robinsonade lacks a pedagogical frame story, where the father tells children about the adventures of Robinson and takes the opportunity to discuss and imitate with children all the actions taken by Robinson the Younger. Due to this and other extirpated parts, the possible target audience was enlarged – besides children and youth, the text was now addressed to adults as well. In accordance with the

  8. La Rencontre à la Porte dorée. Image, texte et contexte

    Directory of Open Access Journals (Sweden)

    Réjane Gay-Canton

    2012-04-01

    Full Text Available À travers l’analyse d’une série de manuscrits allemands illustrés entre le dernier quart du xive siècle et la seconde moitié du xve siècle, l’essai montre que seules de rares images de la Rencontre d’Anne et Joachim à la Porte dorée renvoient à l’Immaculée Conception. Lors de son intégration à la Weltchronik de Heinrich von München et à la Historienbibel, le Marienleben de Bruder Philipp conserve sa position maculiste. Mais dans le second texte, l’image de la Rencontre à la Porte dorée prend une signification différente par l’ajout ou la suppression d’un titulus mentionnant le baiser fécondant. Après avoir observé les résonnances de ces changements sur l’image et souligné l’indépendance de cette dernière face au texte narratif comme à la doctrine théologique, l’essai revient sur l’origine de l’idée du baiser fécondant. Il indique qu’elle n’est ni directement issue des premiers textes littéraires de la conception de Marie que sont les récits apocryphes chrétiens, ni des développements théologiques, mais bien d’un amalgame entre ces deux supports et l’image de la Rencontre à la Porte dorée. L’idée du baiser fécondant reste le propre des illitterati qui trouvèrent en elle un moyen de contourner la théorie augustienne de la transmission du péché originel en attribuant à la future mère de Dieu une conception exempte de toute concupiscence charnelle. Lue sous ce prisme, l’image devient le lieu de projection de l’image mentale. Elle est alors chargée d’un sens nouveau et vient dialoguer avec le texte qu’elle n’illustre plus, mais dont elle offre une lecture parallèle. Au final, seule sa mise en contexte permet de déterminer, au cas par cas, si l’image de la Rencontre renvoie au baiser fécondant et ainsi à l’Immaculée Conception.By analysing a series of illustrated German manuscripts between the last quarter of the xivth century and the second half of the

  9. FOREWORD: 2nd International Workshop on New Computational Methods for Inverse Problems (NCMIP 2012)

    Science.gov (United States)

    Blanc-Féraud, Laure; Joubert, Pierre-Yves

    2012-09-01

    , reduced models for the inversion, non-linear inverse scattering, image reconstruction and restoration, applications (bio-medical imaging, non-destructive evaluation etc). NCMIP 2012 was a one-day workshop. Each of the submitted papers was reviewed by 2 to 4 reviewers. Among the accepted papers, there are 8 oral presentations and 5 posters. Three international speakers were invited for a long talk. This second edition attracted 60 registered attendees in May 2012. NCMIP 2012 was supported by Institut Farman (ENS Cachan) and endorsed by the following French research networks (GDR ISIS, GDR Ondes, GDR MOA, GDR MSPC). The program committee acknowledges the following laboratories CMLA, LMT, LSV, LURPA, SATIE, as well as DIGITEO Network. Laure Blanc-Féraud and Pierre-Yves Joubert Workshop Co-chairs Laure Blanc-Féraud, I3S laboratory, CNRS, France Pierre-Yves Joubert, IEF laboratory, Paris-Sud University, CNRS, France Technical Program Committee Alexandre Baussard, ENSTA Bretagne, Lab-STICC, France Marc Bonnet, ENSTA, ParisTech, France Jerôme Darbon, CMLA, ENS Cachan, CNRS, France Oliver Dorn, School of Mathematics, University of Manchester, UK Mário Figueiredo, Instituto Superior Técnico, Lisbon, Portugal Laurent Fribourg, LSV, ENS Cachan, CNRS, France Marc Lambert, L2S Laboratory, CNRS, SupElec, Paris-Sud University, France Anthony Quinn, Trinity College, Dublin, Ireland Christian Rey, LMT, ENS Cachan, CNRS, France Joachim Weickert, Saarland University, Germany Local Chair Alejandro Mottini, Morpheme group I3S-INRIA Sophie Abriet, SATIE, ENS Cachan, CNRS, France Béatrice Bacquet, SATIE, ENS Cachan, CNRS, France Reviewers Gilles Aubert, J-A Dieudonné Laboratory, CNRS and University of Nice-Sophia Antipolis, France Alexandre Baussard, ENSTA Bretagne, Lab-STICC, France Laure Blanc-Féraud, I3S laboratory, CNRS, France Marc Bonnet, ENSTA, ParisTech, France Jerôme Darbon, CMLA, ENS Cachan, CNRS, France Oliver Dorn, School of Mathematics, University of Manchester, UK G

  10. BOOK REVIEW: Astronomie von Olbers bis Schwarzschild. Nationale Entwicklungen und internationale Beziehungen im 19. Jahrhundert (Acta Historica Astronomiae Vol. 16)

    Science.gov (United States)

    Sterken, C.; Dick, W. R.; Hamel, J.

    2002-12-01

    The 14th volume of the Acta Historica Astronomiae is the Proceedings of a Colloquium International Relationships in Astronomy (in German) organised by the History of Astronomy Section of the Astronomische Gesellschaft held on September 18 in Lilienthal, Germany. The book contains 13 articles on astronomical topics covering the 19th and 20th centuries. The first paper is by Guenther Oestmann and deals with contemporary assessments of Johann Hieronymus Schroeter's (1745-1816) astronomical works and with later judgements of the scientific importance and significance of his observations as seen by astronomers and historians. This report is complemented by a second article on Schroeter's 25-ft reflector in Lilienthal near Bremen. To this end, author Felix Luehning has constructed a scale model of the telescope, and shows how the building of a model brings a deeper understanding of function and handling of this instrument. This brings us to a third paper on telescope building in Lilienthal: Hans-Joachim Leue describes the cooperation of Johann Hieronymus Schroeter and Johann Gottlieb Schrader in developing a white reflecting metal alloy for use as telescope mirror. The fourth article, by Klaus Schillinger, describes on the basis of archival documents the aquisition history of the Herschel telescopes, including telescope quality check, repair and building. Memorial sites referring to Wilhelm Olbers, Johann Hieronymus Schroeter, Friedrich Wilhelm Bessel and Carl Friedrich Gauss are described by Arno Langkavel in two walks outlined in the very last paper of this book. Peter Brosche, in the fifth paper, discusses the rediscovery of Ceres in December1801, a discovery that was the result of the combined efforts of a theoretician (Gauss) and an observer (Zach). Juergen Hamel's paper is based on previously unused archival sources and discusses the outstanding role played by H. C. Schumacher (1780-1850, editor of the Astronomische Nachrichten) in the communication between

  11. Modelling economic losses of historic and present-day high-impact winter storms in Switzerland

    Science.gov (United States)

    Welker, Christoph; Martius, Olivia; Stucki, Peter; Bresch, David; Dierer, Silke; Brönnimann, Stefan

    2015-04-01

    simulate the wind field and related economic impact of both historic and present-day high-impact winter storms in Switzerland since end of the 19th century. Our technique involves the dynamical downscaling of the 20CR to 3 km horizontal resolution using the numerical Weather Research and Forecasting model and the subsequent loss simulation using an open-source impact model. This impact model estimates, for modern economic and social conditions, storm-related economic losses at municipality level, and thus allows a numerical simulation of the impact from both historic and present-day severe winter storms in Switzerland on a relatively fine spatial scale. In this study, we apply the modelling chain to a storm sample of almost 90 high-impact winter storms in Switzerland since 1871, and we are thus able to make a statement of the typical wind and loss patterns of hazardous windstorms in Switzerland. To evaluate our modelling chain, we compare simulated storm losses with insurance loss data for the present-day windstorms "Lothar" and "Joachim" in December 1999 and December 2011, respectively. Our study further includes a range of sensitivity experiments and a discussion of the main sources of uncertainty.

  12. Medicine Goes Female: Protocol for Improving Career Options of Females and Working Conditions for Researching Physicians in Clinical Medical Research by Organizational Transformation and Participatory Design.

    Science.gov (United States)

    Hasebrook, Joachim; Hahnenkamp, Klaus; Buhre, Wolfgang F F A; de Korte-de Boer, Dianne; Hamaekers, Ankie E W; Metelmann, Bibiana; Metelmann, Camila; Bortul, Marina; Palmisano, Silvia; Mellin-Olsen, Jannicke; Macas, Andrius; Andres, Janusz; Prokop-Dorner, Anna; Vymazal, Tomáš; Hinkelmann, Juergen; Rodde, Sibyll; Pfleiderer, Bettina

    2017-08-02

    -research platform. Project results will be published in peer-reviewed journals with high-impact factors. In addition, workshops on gender dimension in research using the principles of Gendered Innovation will be held. Support and consulting services for hospitals will be introduced in order to develop a European consulting service. The main impact of the project will be the implementation of innovative GEP tailored to the needs of university hospitals, which will lead to measurable institutional change in gender equality. This will impact the research at university hospitals in general, and will improve career prospects of female researchers in particular. Simultaneously, the gender dimension in medical research as an innovation factor and mandatory topic will be strengthened and integrated in each individual university hospital research activity. Research funding organizations can use the built knowledge to include mandatory topics for funding applications to enforce the use and implementation of GEP in university hospitals. ©Joachim Hasebrook, Klaus Hahnenkamp, Wolfgang F.F.A. Buhre, Dianne de Korte-de Boer, Ankie E.W. Hamaekers, Bibiana Metelmann, Camila Metelmann, Marina Bortul, Silvia Palmisano, Jannicke Mellin-Olsen, Andrius Macas, Janusz Andres, Anna Prokop-Dorner, Tomáš Vymazal, Juergen Hinkelmann, Sibyll Rodde, Bettina Pfleiderer. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 02.08.2017.

  13. Effect of a Website That Presents Patients' Experiences on Self-Efficacy and Patient Competence of Colorectal Cancer Patients: Web-Based Randomized Controlled Trial.

    Science.gov (United States)

    Giesler, Jürgen M; Keller, Bettina; Repke, Tim; Leonhart, Rainer; Weis, Joachim; Muckelbauer, Rebecca; Rieckmann, Nina; Müller-Nordhorn, Jacqueline; Lucius-Hoene, Gabriele; Holmberg, Christine

    2017-10-13

    krankheitserfahrungen.de. No intervention effects were found at 2 and 6 weeks after baseline. The results of this study do not support the hypothesis that the website studied may increase self-efficacy for coping with cancer or patient competencies such as self-regulation or managing emotional distress. Possible explanations may involve characteristics of the website itself, its use by participants, or methodological reasons. Future studies aimed at evaluating potential effects of websites providing patient experiences on the basis of methodological principles such as those of DIPEx might profit from extending the range of outcome measures, from including additional measures of website usage behavior and users' motivation, and from expanding concepts, such as patient competency to include items that more directly reflect patients' perceived effects of using such a website. Clinicaltrials.gov NCT02157454; https://clinicaltrials.gov/ct2/show/NCT02157454 (Archived by WebCite at http://www.webcitation.org/6syrvwXxi). ©Jürgen M Giesler, Bettina Keller, Tim Repke, Rainer Leonhart, Joachim Weis, Rebecca Muckelbauer, Nina Rieckmann, Jacqueline Müller-Nordhorn, Gabriele Lucius-Hoene, Christine Holmberg. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 13.10.2017.

  14. PREFACE: International Symposium on (e,2e), Double Photoionization and Related Topics & 15th International Symposium on Polarization and Correlation in Electronic and Atomic Collisions

    Science.gov (United States)

    Martin, Nicholas L. S.; deHarak, Bruno A.

    2010-01-01

    44 submitted posters covered recent advances in these topics. These proceedings present papers on 35 of the invited talks. The Local Organizers gratefully acknowledge the financial support of the University of Kentucky College of Arts and Sciences, and the University of Kentucky Department of Physics and Astronomy. We also thank Carol Cotrill, Eva Ellis, Diane Yates, Sarah Crowe, and John Nichols, of the Department of Physics and Astronomy, University of Kentucky for their invaluable assistance in the smooth running of the conferences; Oleksandr Korneta for taking the group photograph; and Emily Martin for helping accompanying persons. Nicholas L S Martin University of Kentucky Bruno A deHarak Illinois Wesleyan University International Scientific Organizing Committee Co-Chairs Don Madison (USA)Klaus Bartschat (USA) Members Lorenzo Avaldi (Italy)Nils Andersen (Denmark) Jamal Berakdar (Germany)Uwe Becker (Germany) Michael Brunger (Australia)Igor Bray (Australia) Greg Childers (USA)Nikolay Cherepkov (Russia) JingKang Deng (China)Albert Crowe (UK) Alexander Dorn (Germany)Danielle Dowek (France) Jim Feagin (USA)Oscar Fojon (Argentina) Nikolay Kabachnik (Russia)Tim Gay (USA) Anatoli Kheifets (Australia)Alexei Grum-Grzhimailo (Russia) George King (UK)Friedrich Hanne (Germany) Tom Kirchner (Germany)Alan Huetz (France) Azzedine Lahmam-Bennani (France)Morty Khakoo (USA) Julian Lower (Australia)Birgit Lohmann (Australia) William McCurdy (USA)Bill McConkey (Canada) Andrew Murray (UK)Rajesh Srivastava (India) Bernard Piraux (Belgium)Al Stauffer (Canada) Tim Reddish (Canada)Jim Williams (Australia) Roberto Rivarola (Argentina)Akira Yagishita (Japan) Michael Schulz (USA)Peter Zetner (Canada) Anthony Starace (USA)Joachim Ullrich (Germany) Giovanni Stefani (Italy)Erich Weigold (Australia) Masahiko Takahashi (Japan) Conference photograph

  15. Photoaging Mobile Apps in School-Based Melanoma Prevention: Pilot Study.

    Science.gov (United States)

    Brinker, Titus Josef; Brieske, Christian Martin; Schaefer, Christoph Matthias; Buslaff, Fabian; Gatzka, Martina; Petri, Maximilian Philip; Sondermann, Wiebke; Schadendorf, Dirk; Stoffels, Ingo; Klode, Joachim

    2017-09-08

    (n=74, 71.8% agreement in skin types 1-2 vs n=50, 53.8% agreement in skin types 3-6) and increased use of sun protection (n=70, 68.0% agreement in skin types 1-2 vs n=52, 55.3% agreement in skin types 3-6), and also positively correlated with higher age. We present a novel way of integrating photoaging in school-based melanoma prevention that affects the students' peer group, considers the predictors of UV exposure in accordance with the theory of planned behavior, and is particularly effective in changing behavioral predictors in fair-skinned adolescents (Fitzpatrick skin types 1-2). Further research is required to evaluate the intervention's prospective effects on adolescents of various cultural backgrounds. ©Titus Josef Brinker, Christian Martin Brieske, Christoph Matthias Schaefer, Fabian Buslaff, Martina Gatzka, Maximilian Philip Petri, Wiebke Sondermann, Dirk Schadendorf, Ingo Stoffels, Joachim Klode. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 08.09.2017.

  16. Mechanical Properties of Gels; Stress from Confined Fluids

    Energy Technology Data Exchange (ETDEWEB)

    George W. Scherer

    2009-12-01

    Garofalini (Rutgers), who has developed the best simulations of water ever reported by use of molecular dynamics. Simulated heating of water in small pores provided quantitative agreement with experiments, and showed that the origin of the high expansion is the altered structure of water in the first two molecular layers adjacent to the pore wall. The final focus of the project was to understand the damage done by crystals growing in small pores. For example, the primary cause of damage to ancient monuments in the Mediterranean Basin is growth of salt crystals in the pores of the stone. Salt may enter stone as a result of capillary rise of groundwater, by leaching of mortar joints, deposition of marine spray, or reactions with atmospheric pollutants (such as oxides of nitrogen or sulfur). As the water evaporates, the salt solution becomes supersaturated and crystals precipitate. Stress results, because the salt usually repels the minerals in the pore walls. Our goal was to identify the factors contributing to the repulsion, so that we could develop a chemical treatment to reduce the repulsion and hence the stress. (We have recently demonstrated an effective treatment as part of a separately funded study.) In collaboration with Prof. Garofalini, molecular dynamics simulations have been done that correctly reproduce the structure of water around dissolved ions of sodium and chloride. We simulated the interaction between crystals of sodium chloride and quartz, and found that this particular system exhibits attractive forces, in agreement with experiment. The origin of the attraction is the orientation of dipolar water molecules near the surfaces of the crystals. Similar calculations now must be done in systems, such as potassium chloride and quartz, where the interaction is repulsive. This grant supported the education of two doctoral students, Hang-Shing Ma (Ph.D., 2002) and Melanie Webb (Ph.D. expected 2010), three post-doctoral researchers, Joachim Gross, Gudrun Reichenauer

  17. Landmarks of History of Soil Science in Sri Lanka

    Science.gov (United States)

    Mapa, R.

    2012-04-01

    Sri Lanka is a tropical Island in the Southern tip of Indian subcontinent positioned at 50 55' to 90 50' N latitude and 790 42' to 810 53' E longitude surrounded by the Indian Ocean. It is an island 435 km in length and 224 km width consisting of a land are of 6.56 million ha with a population of 20 million. In area wise it is ranked as 118th in the world, where at present ranked as 47 in population wise and ranked 19th in population density. The country was under colonial rule under Portuguese, Dutch and British from 1505 to 1948. The majority of the people in the past and present earn their living from activities based on land, which indicates the important of the soil resource. The objective of this paper is to describe the landmarks of the history of Soil Science to highlight the achievements and failures, which is useful to enrich our present understanding of Sri Lankan soils. The landmarks of the history of Soil Science in Sri Lanka can be divided to three phases namely, the early period (prior to 1956), the middle period (1956 to 1972) and the present period (from 1972 onwards). During the early period, detailed analytical studies of coffee and tea soils were compiled, and these gave mainly information on up-country soils which led to fertilizer recommendations based on field trials. In addition, rice and forest soils were also studied in less detail. The first classification of Sri Lankan soils and a provisional soil map based on parent material was published by Joachim in 1945 which is a major landmark of history of Soil Science in Sri Lanka. In 1959 Ponnamperuma proposed a soil classification system for wetland rice soils. From 1963 to 1968 valuable information on the land resource was collected and documented by aerial resource surveys funded by Canada-Ceylon Colombo plan aid project. This covered 18 major river basins and about 1/4th of Sri Lanka, which resulted in producing excellent soil maps and information of the areas called the Kelani Aruvi Ara

  18. Environmental protection congress M-V. Use of regenerative energy sources and hydrogen technology 2010. Proceedings; Klimaschutzkongress M-V. Nutzung regenerativer Energiequellen und Wasserstofftechnik 2010. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    Luschtinetz, Thomas; Lehmann, Jochen (eds.)

    2010-07-01

    Within the Environmental Protection Congress M-V from 4th to 6th November, 2010, in Stralsund (Federal Republic of Germany) the following lectures were held: (1) Conception for climate production in Stralsund (Matthias Ahlhaus); (2) Regenerative energies in the power land North Rhine Westfalia (Frank-Michael Baumann); (3) Heat storages - Supporting pillars of the comprehensive utilization of regenerative ideas (Juergen Buehl); (4) Logistics analysis of rice straw for power exploitations and potential green house gas mitigations - An example in Thailand (Mitra Kami Delivand); (5) The Heatpipe-Reformer registered - Development, start-up and testing (Andreas Dengel); (6) The ecological cost of the use of biomass of plants for energy production (Bohdan Deptula); (7) Hydrogen as fuel and energy storage: Strategy and implementation in NIP (Oliver Ehret); (8) The ORGA test: Development of a testing procedure for a practical evaluation of the fermenter biology and NaWaRo biogas plants (Nils Engler); (9) Large scale integration of offshore wind power through wind farm clusters (Alejandro J. Gesino); (10) NANOSITR - Healt, coldness and electricity from one biomass vessel (Bodo Gross); (11) OPTISTRAHL - A two-stage washer unit for biogas (Bodo Gross); (12) Innovation development for renewable energies (Bernward Janzing); (12) Strategic action options for energy supply utilities at renewable energies (Patrick Kemnitz); (13) Hydrogen - An option for a sustainable storage of wind power (Martin Kleimaier); (14) Small parabolic trough power plants - Actual technology and outlook (Joachim Krueger); (15) A photocatalytic generation of hydrogen: Efficient iron-based water reduction catalysts (Sebastian Losse); (16) Environmental assessment of municipal solid waste management in Sri Lanka and India in a life cycle perspective (Samanthi Nirmala M. Menikpura); (17) High temperature low sag conductors in power system with wind power farms (Olgierd Malyszka); (18) Wind

  19. Chromium-rich lawsonite in high-Cr eclogites from the Făgăras Massif (South Carpathians)

    Science.gov (United States)

    Negulescu, E.; Săbău, G.

    2012-12-01

    (2004). These conditions fall still inside the stability field of lawsonite, below the thermal breakdown of this phase (Pawley, 1994), and consistent with its metastable persistence as armoured relics, during a near-isobaric late stage heating episode recorded in eclogites from the same structural setting (Săbău & Negulescu, 2006). Acknowledgements Financial support by grant PN-II-ID-PCE-2011-3-0030 Romanian Executive Unit for Financing Higher Education, Research, Development and Innovation. Prof. Hans-Joachim Masonne kindly provided access to the analytical facilities at Institut für Mineralogie und Kristallchemie in Stuttgart. References Brandelik, A., Massonne, H.-J. (2004). PTGIBBS - an Excel™ Visual Basic program for computing and visualizing thermodynamic functions and equilibria of rock-forming minerals. Computers and Geosciences 30, 909-923. Pawley, A. (1994) The pressure and temperature stability limits of lawsonite: Implication for H2O recycling in subduction zones. Contrib. Mineral. Petrol. 118, 99-108. Săbău, G., Negulescu, E. (2006) Metamorphic forming and evolution conditions of the eclogites in the Topolog Complex, Făgăras Mountains. Romanian Journal of Petrology 78, 39-46.

  20. Evolution of Cognitive Rehabilitation After Stroke From Traditional Techniques to Smart and Personalized Home-Based Information and Communication Technology Systems: Literature Review.

    Science.gov (United States)

    Cogollor, José M; Rojo-Lacal, Javier; Hermsdörfer, Joachim; Ferre, Manuel; Arredondo Waldmeyer, Maria Teresa; Giachritsis, Christos; Armstrong, Alan; Breñosa Martinez, Jose Manuel; Bautista Loza, Doris Anabelle; Sebastián, José María

    2018-03-26

    the selection of 8 different ICT-based approaches found in scientific-technical studies, 9 European projects funded by the European Commission that offer eHealth architectures, and other large-scale activities such as smart houses and the initiative City4Age. Stroke is one of the main causes that most negatively affect countries in the socioeconomic aspect. The design of new ICT-based systems should provide 4 main features for an efficient and personalized cognitive rehabilitation: support in the execution of complex daily tasks, automatic error detection, home-based performance, and accessibility. Only 33% of the European projects presented fulfilled those requirements at the same time. For this reason, current and future large-scale initiatives focused on eHealth and smart environments should try to solve this situation by providing more complete and sophisticated platforms. ©José M Cogollor, Javier Rojo-Lacal, Joachim Hermsdörfer, Manuel Ferre, Maria Teresa Arredondo Waldmeyer, Christos Giachritsis, Alan Armstrong, Jose Manuel Breñosa Martinez, Doris Anabelle Bautista Loza, José María Sebastián. Originally published in JMIR Rehabilitation and Assistive Technology (http://rehab.jmir.org), 26.03.2018.

  1. The 3T3 neutral red uptake phototoxicity test: practical experience and implications for phototoxicity testing--the report of an ECVAM-EFPIA workshop.

    Science.gov (United States)

    Ceridono, Mara; Tellner, Pär; Bauer, Daniel; Barroso, João; Alépée, Nathalie; Corvi, Raffaella; De Smedt, Ann; Fellows, Mick D; Gibbs, Neil K; Heisler, Eckhard; Jacobs, Abigail; Jirova, Dagmar; Jones, David; Kandárová, Helena; Kasper, Peter; Akunda, Jacqueline Kinyamu; Krul, Cyrille; Learn, Douglas; Liebsch, Manfred; Lynch, Anthony M; Muster, Wolfgang; Nakamura, Kazuichi; Nash, J Frank; Pfannenbecker, Uwe; Phillips, Gareth; Robles, Catherine; Rogiers, Vera; Van De Water, Femke; Liminga, Ulla Wändel; Vohr, Hans-Werner; Wattrelos, Olivier; Woods, Julie; Zuang, Valérie; Kreysa, Joachim; Wilcox, Phil

    2012-08-01

    This is the report from the "ECVAM-EFPIA workshop on 3T3 NRU Phototoxicity Test: Practical Experience and Implications for Phototoxicity Testing", jointly organized by ECVAM and EFPIA and held on the 25-27 October 2010 in Somma Lombardo, Italy. The European Centre for the Validation of Alternative Methods (ECVAM) was established in 1991 within the European Commission Joint Research, based on a Communication from the European Commission (1991). The main objective of ECVAM is to promote the scientific and regulatory acceptance of alternative methods which are of importance to the biosciences and which reduce, refine and replace the use of laboratory animals. The European Federation of Pharmaceuticals Industries and Association (EFPIA) represent the pharmaceutical industry operating in Europe. Through its direct membership of 31 national associations and 40 leading pharmaceutical companies, EFPIA is the voice on the EU scene of 2200 companies committed to researching, developing and bringing to patients new medicines that improve health and the quality of life around the world. The workshop, co-chaired by Joachim Kreysa (ECVAM) and Phil Wilcox (GSK, EFPIA) involved thirty-five experts from academia, regulatory authorities and industry, invited to contribute with their experiences in the field of phototoxicology. The main objectives of the workshop were: -to present 'in use' experience of the pharmaceutical industry with the 3T3 Neutral Red Uptake Phototoxicity Test (3T3 NRU-PT), -to discuss why it differs from the results in the original validation exercise, -to discuss technical issues and consider ways to improve the usability of the 3T3 NRU-PT for (non-topical) pharmaceuticals, e.g., by modifying the threshold of chemical light absorption to trigger photo-toxicological testing, and by modifying technical aspects of the assay, or adjusting the criteria used to classify a positive response. During the workshop, the assay methodology was reviewed by comparing the OECD

  2. The Impact of Advice Seekers' Need Salience and Doctors' Communication Style on Attitude and Decision Making: A Web-Based Mammography Consultation Role Play.

    Science.gov (United States)

    Fissler, Tim; Bientzle, Martina; Cress, Ulrike; Kimmerle, Joachim

    2015-09-08

    style, while participants without salient needs did not. When the physician used a need-oriented communication style, those participants with salient needs had a more positive attitude toward mammography after the consultation than before (mean 0.13, SD 0.54), while they changed their attitude in a negative direction when confronted with a purely fact-oriented communication style (mean -0.35, SD 0.80). The same applied to decision modification (need-oriented: mean 0.10, SD 0.99; fact-oriented: mean -0.30, SD 0.88). The findings underline the importance of communicating in a need-oriented style with patients and advice seekers who are aware of their personal needs. Ignoring the needs of those people appears to be particularly problematic. So physicians' sensitivity for advice seekers' currently relevant needs is essential. ©Tim Fissler, Martina Bientzle, Ulrike Cress, Joachim Kimmerle. Originally published in JMIR Cancer (http://cancer.jmir.org), 08.09.2015.

  3. Comparison of cellular effects of starch-coated SPIONs and poly(lactic-co-glycolic acid matrix nanoparticles on human monocytes

    Directory of Open Access Journals (Sweden)

    Gonnissen D

    2016-10-01

    Full Text Available Dominik Gonnissen,1 Ying Qu,1,2 Klaus Langer,3 Cengiz Öztürk,4 Yuliang Zhao,2 Chunying Chen,2 Guiscard Seebohm,5 Martina Düfer,6 Harald Fuchs,1 Hans-Joachim Galla,7 Kristina Riehemann11Center for Nanotechnology, Institute of Physics, University of Münster, Münster, Germany; 2National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing, People’s Republic of China; 3Institute of Pharmaceutical Technology and Biopharmacy, University of Münster, Münster, 4chemicell GmbH, Berlin, 5Department of Cardiovascular Medicine, Institute for Genetics of Heart Diseases, University Hospital Münster, 6Department of Pharmacology, Institute of Pharmaceutical and Medicinal Chemistry, 7Department of Cell Biology/Biophysics, Institute of Biochemistry, University of Münster, Münster, GermanyAbstract: Within the last years, progress has been made in the knowledge of the properties of medically used nanoparticles and their toxic effects, but still, little is known about their influence on cellular processes of immune cells. The aim of our comparative study was to present the influence of two different nanoparticle types on subcellular processes of primary monocytes and the leukemic monocyte cell line MM6. We used core-shell starch-coated superparamagnetic iron oxide nanoparticles (SPIONs and matrix poly(lactic-co-glycolic acid (PLGA nanoparticles for our experiments. In addition to typical biocompatibility testing like the detection of necrosis or secretion of interleukins (ILs, we investigated the impact of these nanoparticles on the actin cytoskeleton and the two voltage-gated potassium channels Kv1.3 and Kv7.1. Induction of necrosis was not seen for PLGA nanoparticles and SPIONs in primary monocytes and MM6 cells. Likewise, no alteration in secretion of IL-1β and IL-10 was detected under the same experimental conditions. In contrast, IL-6 secretion was exclusively downregulated in primary monocytes after contact with both

  4. Electronic-Based Patient-Reported Outcomes: Willingness, Needs, and Barriers in Adjuvant and Metastatic Breast Cancer Patients.

    Science.gov (United States)

    Hartkopf, Andreas D; Graf, Joachim; Simoes, Elisabeth; Keilmann, Lucia; Sickenberger, Nina; Gass, Paul; Wallwiener, Diethelm; Matthies, Lina; Taran, Florin-Andrei; Lux, Michael P; Wallwiener, Stephanie; Belleville, Eric; Sohn, Christof; Fasching, Peter A; Schneeweiss, Andreas; Brucker, Sara Y; Wallwiener, Markus

    2017-08-07

    differences were found in relation to willingness to use ePRO (92.3% in the exposed group vs 59% in the nonexposed group; P=.001). Multiple barriers were identified, and most of them showed statistically significant differences in favor of the exposed patients (ie, data security [13% in the exposed patients vs 30% in the nonexposed patients; P=.003] and no prior technology usage [5% in the exposed group vs 15% in the nonexposed group; P=.02]), whereas the differences in disease burden (somatic dimension: 4% in the exposed group vs 9% in the nonexposed group; P=.13) showed no significance. In nonexposed patients, requests for support services were identified, which could increase their ePRO willingness. Significant barriers in relation to HRQoL, cancer-related restrictions, and especially the setting of the survey were identified in this trial. Thus, it is necessary to address and eliminate these barriers to ensure data accuracy and reliability for future ePRO assessments. Exposure seems to be a potential option to increase willingness to use ePRO and to reduce barriers. ©Andreas D Hartkopf, Joachim Graf, Elisabeth Simoes, Lucia Keilmann, Nina Sickenberger, Paul Gass, Diethelm Wallwiener, Lina Matthies, Florin-Andrei Taran, Michael P Lux, Stephanie Wallwiener, Eric Belleville, Christof Sohn, Peter A Fasching, Andreas Schneeweiss, Sara Y Brucker, Markus Wallwiener. Originally published in JMIR Cancer (http://cancer.jmir.org), 07.08.2017.

  5. Acceptance of a reusable self-injection device for recombinant human growth hormone: final data from a questionnaire-based, cross-sectional, international, multicenter, observational study in pediatric patients

    Directory of Open Access Journals (Sweden)

    Schnabel D

    2016-09-01

    Full Text Available Dirk Schnabel,1 Carl-Joachim Partsch,2 Muriel Houang,3 Sarah Ehtisham,4 Helen Johnstone,5 Markus Zabransky,6 Wieland Kiess7 1Pediatric Endocrinology, Center for Chronic Sick Children, Otto-Heubner-Centrum für Kinder- und Jugendmedizin, Charite, University Medicine, Berlin, Germany; 2Endokrinologikum Hamburg, Hamburg, Germany; 3Explorations Fonctionnelles Endocriniennes, Hôpital Armand Trousseau, Paris, France; 4Mediclinic City Hospital, Dubai Healthcare City, Dubai, United Arab Emirates; 5The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK; 6Sandoz International GmbH, Holzkirchen, 7Department of Women and Child Health, Hospital for Children and Adolescents, University Hospitals, University of Leipzig, Leipzig, Germany Background: A questionnaire-based survey was conducted to assess attitudes toward a reusable self-injection system (SurePal™ among pediatric patients with growth disturbances who were prescribed treatment with Omnitrope® within routine clinical practice.Methods: This was a multicenter, observational study, incorporated into the noninterventional PAtients TReated with Omnitrope® (PATRO Children study. Included subjects, or their caregivers, completed a questionnaire on the following five main areas: attractiveness of SurePal™, training received, using the device, the low drug wastage system, and experience versus other devices used previously (pretreated patients. Responses were based on a 5-point scale, with 2 being the best possible outcome and −2 the worst possible outcome.Results: In total, 550 patients were included in this study (338 from France, 169 from Germany, and 43 from the UK. The mean age ± standard deviation of participants was 10.8±3.5 years; the majority (57% were male and growth hormone treatment naïve (88%. Almost half (49.8% of children prepared their SurePal™ for injection themselves and 45.5% performed injections themselves. As patients progressed into their teens, the majority

  6. Biogas in the agriculture. State of the art. Proceedings; Biogas in der Landwirtschaft. Stand und Perspektiven. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    Within the meeting of the Association for Technology and Structures in Agriculture (Darmstadt, Federal Republic of Germany) and the Agency for Renewable Resources (Guelzow, Federal Republic of Germany) between 15th and 16th September, 2009, in Weimar the following lectures were held: (1) Results of the actual biogas measurement II (Peter Weiland); (2) Agitators in biogas plants - Technology with central significance (Kay Rostalski); (3) How much energy is needed by a biogas fermenter? (Ludwig Heinloth); (4) The fermentation concept of Rueckert NatUrgas GmbH (Claus Rueckert, Dominique Pfeufer); (5) Experiences from the construction for the practice of the company MT-Energie GmbH (Bodo Drescher); (6) Fermenter/technology concept of Schmack Biogas AG (Thomas Moeeslinger); (7) Transport of biomass - How much does the logistics of Guelle and Co. cost? (Thore Toews); (8) Which factors determine the efficiency of biogas plants? (Gerd Reinhold); (9) Microbial diversity in biogas reactors in the fermentation of renewable raw materials (Michael Klocke et al.); (10) What do additives and ingredients contribute to the optimisation of the production of biogas? (Udo Hoelker); (11) Process optimisation - An interaction between technology and microbiology (Andreas Gronauer et al.); (12) Emissions at the production of biogas - an analysis if the environmental relevance (Joachim Clemens et al.); (13) Support systems for energy plants - Consequences to soil and environment (Matthias Willms et al.); (14) How ecological is biogas? (Sven Gaertner); (15) Biogas plant - Analysis of construction and operation from licensing view (Hans-Walter Schneichel); (16) Biogas plants - Analysis of construction and operation from contractual legal view (Florian Valentin); (17) Biogasplants - Analysis of construction and operation from remuneration legal view (Helmut Loibl); (18) Process and costs of treatment of residues of fermentation (Sebastian Wulf, Helmut Doehler); (19) How do residues of

  7. CHAIRMEN'S FOREWORD: The Seventh International Conference on New Phenomena in Mesoscopic Structures & The Fifth International Conference on Surfaces and Interfaces of Mesoscopic Devices

    Science.gov (United States)

    Aoyagi, Yoshinobu; Goodnick, Stephen M.

    2006-05-01

    , non-equilibrium transport, instabilities, nano-electro-mechanical systems, mesoscopic Josephson effects, phase coherence and breaking, and the Kondo effect •Systems of nanodevices: Quantum cellular automata, systolic SET processors, quantum neural nets, adaptive effects in circuits, and molecular circuits •Nanomaterials: nanotubes, nanowires, organic and molecular materials, self-assembled nano wires, and organic devices •Nanobioelectronics: electronic properties of biological structures on the nanoscale. This year's conference was organized by Prof Stephen Goodnick, Arizona State University, and Prof Yoshinobu Aoyagi, Tokyo Institute of Technology. The conference benefited from 14 invited speakers, whose topics spanned the above list, and a total of 97 registered attendees. The largest contingent was from Japan, followed closely by the US. In total, there were 49 from Japan, 31 fiom the US, and 17 from Europe. The organizers want to especially thank the sponsors for the meeting: The Office of Naval Research, the Army Research Office, and Arizona State University on the US side, and the Japan Society for the Promotion of Science, through their 151 Committee, on the Japanese side. PROGRAM COMMITTEE •Prof Gerhard Abstreiter, Technical University of Munich •Prof Tsuneya Ando, Tokyo Institute of Technology •Prof John Barker, University of Glasgow •Prof Jonathan Bird, the University at Buffalo •Prof Robert Blick, University of Wisconsin •Prof David Ferry, Chair, Arizona State University •Dr Yoshiro Hirayama, NTT Basic Research Laboratories •Dr Koji Ishibashi, RIKEN •Prof Carlo Jacoboni, University of Modena •Prof David Janes, Purdue University •Prof Friedl Kuchar, University of Leoben •Prof K. Matsumoto, Osaka University •Prof Wolfgang Porod, Notre Dame University •Prof Michiharu Tabe, Shizuoka University •Prof Joachim Wolter, Eindhoven Institute of Technology •Prof Lukas Worschech, University of Würzburg •Dr Naoki Yokoyama, Fujitsu

  8. PREFACE: XXVIth International Conference on Photonic, Electronic and Atomic Collisions

    Science.gov (United States)

    Orel, Ann; Starace, Anthony F.; Nikolić, Dragan; Berrah, Nora; Gorczyca, Thomas W.; Kamber, Emanuel Y.; Tanis, John A.

    2009-12-01

    (US DOE) gave a talk on 'Facing Our Energy Challenges in a New Era of Science' and William Phillips (Nobel laureate, NIST) presented a talk on 'Time, Einstein, and the Coolest Stuff in the Universe'. These public talks, held on Thursday and Friday evenings, respectively, were very accessible to a general audience. In addition, there were 61 progress reports on ongoing current research, and 26 special reports selected from the submitted abstracts based on their relevance and importance. These talks covered the full range of the conference topics. Notably, this was the 50th anniversary of ICPEAC and a formal session was held the first day to honor the event as well as those who were instrumental in initiating the conference. Thirteen scientists, representing both those from the early days of ICPEAC as well as chairs of previous ICPEACs, were present and called to the stage, including Benjamin Bederson, Lewis Branscomb, Robert Crompton, Alexander Dalgarno, Gordon Dunn, Werner Eissner, Brian Gilbody, Edward Gerjuoy, Hartmut Hotop, Eugen Merzbacher, Eugene Rudd, Felix Smith, and Aaron Temkin. Steven Manson was the chair of the session and he introduced those present from the early days. Joachim Burgdörfer presented an overview of the history of ICPEAC. This session was followed by a special anniversary reception to honor all of the early 'ICPEACers'. Generous support for the conference was provided by IUPAP, the WMU President's office, and the National Science Foundation. The funds were sizeable, timely, and greatly appreciated, and permitted us to support a significant number of young scientists (postdocs and students) and persons from developing/disadvantaged countries. Nevertheless, the number of requests was far greater than the total support available (by about a factor of five!), and we had to turn down many financial requests. We encourage the organizers of the next ICPEAC to seek a higher level of funding for supporting young scientists and scientists from

  9. PREFACE: NC-AFM 2005: Proceedings of the 8th International Conference on Non-Contact Atomic Force Microscopy

    Science.gov (United States)

    Reichling, M.; Mikosch, W.

    2006-04-01

    formation allow the highly resolved measurement of a number of physical properties far beyond the determination of surface topography. The development of techniques allowing atomic resolution dynamic mode imaging in liquids pushes the door open for an atomic precision analysis of biological samples under physiological conditions. In each of these fields, the conference demonstrated cutting-edge results and also provided perspectives for the next steps on the roadmap of NC-AFM towards the development of its full extent. The conference in Bad Essen was made possible by the continuous dedication of the local management and we are most grateful to Frauke Riemann, Joachim Fontaine and the members of the supporting team for the smooth organization. We gratefully appreciate the financial support of the exhibitors, namely Anfatec, HALCYONICS, JEOL, LOT-Oriel, NanoMagnetics, NT-MDT, Omicron, Schaefer Technology, SURFACE, UNISOKU and the local sponsors which enabled us to provide free participation at the conference for ten promising young researchers who had submitted excellent contributions. It was a great pleasure for us to continue our most successful collaboration with Nanotechnology as our partner for the proceedings publication and we would like to thank Ian Forbes and the publishing team for the professional handling of the peer review and all production matters.

  10. Metronomic treatment of advanced non-small-cell lung cancer with daily oral vinorelbine – a Phase I trial

    Directory of Open Access Journals (Sweden)

    Guetz S

    2017-02-01

    Full Text Available Sylvia Guetz,1,* Amanda Tufman,2,* Joachim von Pawel,3 Achim Rittmeyer,4 Astrid Borgmeier,2 Pierre Ferré,5 Birgit Edlich,6 Rudolf Maria Huber2 1Ev. Diakonissenkrankenhaus Leipzig, Leipzig, 2University Hospital Munich and Thoracic Oncology Centre Munich, Member of the German Center for Lung Research, Comprehensive Pneumology Center Munich (DZL CPC-M, Munich, 3Asklepios Fachkliniken Muenchen-Gauting, Gauting, 4Lungenfachklinik Immenhausen, Immenhausen, Germany; 5Pierre Fabre Pharmaceuticals, Oncology Research and Development Center, Toulouse, France; 6Pierre Fabre Pharma GmbH, Freiburg, Germany *These authors contributed equally to this work Micro-abstract: In a Phase I dose-finding study of metronomic daily oral vinorelbine in advanced non-small-cell lung cancer, a recommended dose was established for this therapeutic approach. In addition, this trial revealed promising efficacy data and an acceptable tolerability profile. The observed vinorelbine blood concentrations suggest continuous anti-angiogenic coverage. Introduction: We present a Phase I dose-finding study investigating metronomic daily oral vinorelbine (Navelbine® Oral, NVBo in advanced non-small-cell lung cancer (NSCLC. Patients and methods: Patients with stage III/IV NSCLC received daily NVBo at fixed dose levels of 20–50 mg/d for 21 days of each 4-week cycle. Primary end point was the maximum tolerated dose. Secondary end points included tumor response, time to progression (TTP, overall survival (OS and tolerability. Results: Twenty-seven patients with advanced NSCLC were enrolled. Most of them were extensively pretreated. Daily NVBo was well tolerated up to 30 mg/d. At 40 mg/d, two of five patients experienced dose-limiting toxicities (DLTs. Three of six patients had DLTs at the 50 mg/d level. The recommended dose was established at 30 mg/d in cycle 1, with escalation to 40 mg/d in cycle 2, if tolerated. Pharmacokinetic analyses showed continuous blood exposure over 21

  11. Securing the Continuity of Medical Competence in Times of Demographic Change: A Proposal.

    Science.gov (United States)

    Hasebrook, Joachim Paul; Hinkelmann, Jürgen; Volkert, Thomas; Rodde, Sibyll; Hahnenkamp, Klaus

    2016-12-21

    consensus about the implementation of relevant factors in order to improve employee retention. We expect these consensus groups to develop and introduce measures for more structured training procedures, individual and team incentives, organizational guidelines for better recruiting and retention in hospitals, models of flexible and attractive working conditions including shift work and vacation planning, and use of new learning tools (eg, tablet PCs and mobile phones). All measures are implemented in the Department of Anaesthesiology, Intensive Care, Emergency Care and Pain Medicine at the University Hospital Muenster (UKM) with approximately 150 physicians and in the further 44 departments of the UKM and 22 teaching hospitals, which all together employ more than 5000 physicians. The measures will also be implemented at the university hospitals in Aachen, Rostock, and Greifswald. All decisions and measures will be discussed with representatives from hospital management and professional associations. Results will be presented at conferences and published in journals. ©Joachim Paul Hasebrook, Jürgen Hinkelmann, Thomas Volkert, Sibyll Rodde, Klaus Hahnenkamp. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 21.12.2016.

  12. A Medical Student-Delivered Smoking Prevention Program, Education Against Tobacco, for Secondary Schools in Germany: Randomized Controlled Trial.

    Science.gov (United States)

    Brinker, Titus Josef; Owczarek, Andreas Dawid; Seeger, Werner; Groneberg, David Alexander; Brieske, Christian Martin; Jansen, Philipp; Klode, Joachim; Stoffels, Ingo; Schadendorf, Dirk; Izar, Benjamin; Fries, Fabian Norbert; Hofmann, Felix Johannes

    2017-06-06

    ]=68). Notable differences were observed between the groups for the female gender (4.2% to 9.5% for control vs 4.0% to 5.2% for intervention; NNT=24 for females vs NNT=207 for males), low educational background (7.3% to 12% for control vs 6.1% to 8.7% for intervention; NNT=30), and migrational background (students who claimed that at least one parent was not born in Germany) at the 12-month follow-up. The intervention appears to prevent smoking onset (NNT=63) but does not appear to initiate quitting. The intervention appears to prevent smoking, especially in females and students with a low educational background. ©Titus Josef Brinker, Andreas Dawid Owczarek, Werner Seeger, David Alexander Groneberg, Christian Martin Brieske, Philipp Jansen, Joachim Klode, Ingo Stoffels, Dirk Schadendorf, Benjamin Izar, Fabian Norbert Fries, Felix Johannes Hofmann. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 06.06.2017.

  13. EDITORIAL: From reciprocal space to real space in surface science From reciprocal space to real space in surface science

    Science.gov (United States)

    Bartels, Ludwig; Ernst, Karl-Heinz

    2012-09-01

    and Hans-Joachim Freund Mapping the first electronic resonances of a Cu phthalocyanine STM tunnel junctionW-H Soe, C Manzano, H S Wong and C Joachim Epitaxial Bi allotropes on quasicrystal surfaces as templates for adsorption of pentacene and fullereneH R Sharma, J A Smerdon, K M Young and R McGrath Island formation and manipulation of prochiral azobenzene derivatives on Au(111)Sofia Selvanathan, Maike V Peters, Stefan Hecht and Leonhard Grill

  14. Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion

    Science.gov (United States)

    Henry, David A; Carless, Paul A; Moxey, Annette J; O’Connell, Dianne; Stokes, Barrie J; Fergusson, Dean A; Ker, Katharine

    2014-01-01

    Background Concerns regarding the safety of transfused blood have led to the development of a range of interventions to minimise blood loss during major surgery. Anti-fibrinolytic drugs are widely used, particularly in cardiac surgery, and previous reviews have found them to be effective in reducing blood loss, the need for transfusion, and the need for re-operation due to continued or recurrent bleeding. In the last few years questions have been raised regarding the comparative performance of the drugs. The safety of the most popular agent, aprotinin, has been challenged, and it was withdrawn from world markets in May 2008 because of concerns that it increased the risk of cardiovascular complications and death. Objectives To assess the comparative effects of the anti-fibrinolytic drugs aprotinin, tranexamic acid (TXA), and epsilon aminocaproic acid (EACA) on blood loss during surgery, the need for red blood cell (RBC) transfusion, and adverse events, particularly vascular occlusion, renal dysfunction, and death. Search methods We searched: the Cochrane Injuries Group’s Specialised Register (July 2010), Cochrane Central Register of Controlled Trials (The Cochrane Library 2010, Issue 3), MEDLINE (Ovid SP) 1950 to July 2010, EMBASE (Ovid SP) 1980 to July 2010. References in identified trials and review articles were checked and trial authors were contacted to identify any additional studies. The searches were last updated in July 2010. Selection criteria Randomised controlled trials (RCTs) of anti-fibrinolytic drugs in adults scheduled for non-urgent surgery. Eligible trials compared anti-fibrinolytic drugs with placebo (or no treatment), or with each other. Data collection and analysis Two authors independently assessed trial quality and extracted data. This version of the review includes a sensitivity analysis excluding trials authored by Prof. Joachim Boldt. Main results This review summarises data from 252 RCTs that recruited over 25,000 participants. Data from

  15. St. Patrick's Day 2015 geomagnetic storm analysis based on Real Time Ionosphere Monitoring

    Science.gov (United States)

    García-Rigo, Alberto

    2017-04-01

    Alberto García-Rigo (1), David Roma-Dollase (2), Manuel Hernández-Pajares (1), Zishen Li (3), Michael Terkildsen (4), German Olivares (4), Reza Ghoddousi-Fard (5), Denise Dettmering (6), Eren Erdogan (6), Haris Haralambous (7), Yannick Béniguel (8), Jens Berdermann (9), Martin Kriegel (9), Anna Krypiak-Gregorczyk (10), Tamara Gulyaeva (11), Attila Komjathy (12), Panagiotis Vergados (12), Joachim Feltens (13,19), René Zandbergen (13), Tim Fuller-Rowell (14), David Altadill (15), Nicolas Bergeot (16), Andrzej Krankowski (17), Loukis Agrotis (18), Ivan Galkin (20), Raul Orus-Perez (21) 1. UPC-IonSAT research group, Technical University of Catalonia, Spain 2. Department of Engineering: Electronics, University of Barcelona (UB), Spain 3. Academy of Opto-Electronics, Chinese Academy of Sciences (CAS), China 4. Bureau of Meteorology, Space Weather Services, Australia 5. Canadian Geodetic Survey, Natural Resources Canada (NRCan) / Government of Canada, Canada 6. Deutsches Geodätisches Forschungsinstitut der Technischen Universität München (DGFI-TUM), Germany 7. Frederick University Cyprus, Cyprus 8. IEEA, France 9. Institute of Communications and Navigation, DLR, Germany 10. Institute of Geodesy, UWM, Poland 11. Institute of Terrestrial Magnetism, ionosphere and Radio Wave Propagation, Russian Academy of Sciences, Russia 12. NASA - Jet Propulsion Laboratory (JPL), California Institute of Technology, USA 13. Navigation Support Office, ESA-ESOC, Germany 14. NOAA affiliate, USA 15. Observatori de l'Ebre (OE), CSIC - Universitat Ramon Llull, 43520 Roquetes, Spain 16. Planetology and Reference Systems, Royal Observatory of Belgium (ROB), Belgium 17. Space Radio-Diagnostics Research Centre, UWM (SRRC/UWM), Poland 18. SYMBAN Limited, ESA-ESOC, Germany 19. Telespazio VEGA Deutschland GmbH c/o ESA-ESOC, Germany 20. University of Massachusetts Lowell, Space Science Lab, USA 21. Wave Interaction and Propagation Section (TEC-EEP), ESA-ESTEC, The Netherlands IAG's Real Time

  16. EDITORIAL More than a wire More than a wire

    Science.gov (United States)

    Demming, Anna

    2010-10-01

    commercial stages, these one-dimensional structures have a number of advantages including the lower melting point of materials at the nanoscale and the potential for further reductions in size and programming current and power requirements. Investigations of one-dimensional structures have provided an enduring stimulant to both fundamental and applied research in nanoscale science and technology research. William Plomer once described creativity as 'the ability to connect the apparently unconnected'. It could perhaps be said that nanowires bring creativity to the ability to connect. References [1] Joachim C, Rousset B, Schonenberger C, Kerrien A, Druet E and Chevalier J 1991 Nanotechnology 2 96 [2] Brandbyge M, Schiotz J, Sorensen M R, Stpltze P, Jacobsen K W and Norskov J K 1995 Phys. Rev. B 52 8499-514 [3] Dai K and Haynie D T 2006 Nanotechnology 17 R14-R25 [4] Snider G S and Williams R S 2007 Nanotechnology 18 035204 [5] Li B, Luo Z, Shi L, Zhou J, Rabenberg L, Ho P S, Allen R A and Cresswell M W 2009 Nanotechnology 20 085304 [6] Liao L, Zhang Z, Yan B, Zheng Z, Bao Q L, Wu T, Li C M, Shen Z X, Zhang J X, Gong H, Li J C and Yu T 2009 Nanotechnology 20 085203 [7] Chung A, Deen J, Lee J-S and Meyyappan M 2010 Nanotechnology 21 412001

  17. Books Noted

    Science.gov (United States)

    Walsh, Edward J.

    1999-10-01

    .00. Environmental Soil and Water Chemistry: Principles and Applications V. P. Evangelou. Wiley-Interscience: New York, 1998. xix + 564 pp. ISBN 0-471-16515-8. 79.95. 1001 Chemicals in Everyday Products, 2nd edition Grace Ross Lewis. Wiley-Interscience: New York, 1999. x + 388 pp. ISBN 0-471-29212-5. 39.95. Organic Coatings: Science and Technology, 2nd edition Zeno W. Wicks Jr., Frank N. Jones, and S. Peter Pappas. Wiley-Interscience: New York, 1999. xxi + 630 pp. ISBN 0-471-24507-0. 125.00. Progress in Inorganic Chemistry, Vol. 48 Kenneth D. Karlin, Ed. Wiley-Interscience: New York, 1999. vi + 603 pp. ISBN 0-471-32623-2. 145.00. Occupational Biomechanics, 3rd edition Don B. Chaffin, Gunnar B. Andersson, and Bernard J. Martin. Wiley-Interscience: New York, 1999. xvii + 579 pp. ISBN 0-471-24697-2. 69.95. Advances in Photochemistry, Vol. 25 Douglas C. Neckers, David H. Volman, and Gunther Von Bünau. Wiley-Interscience: New York, 1999. xi + 238 pp. ISBN 0-471-32708-5. 110.00. Distillation Johann G. Stichlmair and James R. Fair. Wiley-VCH: New York, 1998. xiii + 524 pp. ISBN 0-471-25241-7. 94.95. Ammonia - Principles and Industrial Practice Maz Appl. Wiley-VCH: New York, 1999. ix + 301 pp. ISBN 3-527-29593-3. 160.00. Precursor-Derived Ceramics: Synthesis, Structure, and High-Temperature Mechanical Properties Fritz Aldinger, Fumihiro Wakai, and Joachim Bill, Eds. Wiley-VCH: New York, 1999. xv + 298 pp. ISBN 3-527-29814-2. 180.00. Advances in Sonochemisty, Vol. 5 Timothy J. Mason. JAI Press: Stamford, CT, 1999. xi + 311 pp. ISBN 0-7623-0331-x. 109.50. Fluid Metals: The Liquid-Vapor Transition of Metals Friedrich Hensel and William W. Warren Jr. Princeton University Press: Princeton, NJ. 1999. xvii + 243 pp. ISBN 0-691-05830-x. 69.50. Direct Phasing in Crystallography: Fundamentals and Applications Carmelo Giacovazzo. Oxford University Press: New York, 1999. xxiii + 767 pp. ISBN 0-19-850072-6. 140.00. Practical Environmental Analysis M. Radojevic and V. N. Bashkin. Royal Society of

  18. EDITORIAL: Focus on Quantum Control

    Science.gov (United States)

    Rabitz, Herschel

    2009-10-01

    , Yuri Khodorkovsky, Yehiam Prior and Ilya Sh Averbukh Optimal control of interacting particles: a multi-configuration time-dependent Hartree-Fock approach Michael Mundt and David J Tannor Exact quantum dissipative dynamics under external time-dependent driving fields Jian Xu, Rui-Xue Xu and Yi Jing Yan Pulse trains in molecular dynamics and coherent spectroscopy: a theoretical study J Voll and R de Vivie-Riedle Quantum control of electron localization in molecules driven by trains of half-cycle pulses Emil Persson, Joachim Burgdorfer and Stefanie Grafe Quantum control design by Lyapunov trajectory tracking for dipole and polarizability coupling Jean-Michel Coron, Andreea Grigoriu, Catalin Lefter and Gabriel Turinici Sliding mode control of quantum systems Daoyi Dong and Ian R Petersen Implementation of fault-tolerant quantum logic gates via optimal control R Nigmatullin and S G Schirmer Generalized filtering of laser fields in optimal control theory: application to symmetry filtering of quantum gate operations Markus Schroder and Alex Brown

  19. BOOK REVIEW: Carl Christian Bruhns - Ein bedeutender Naturwissenschaftler in der zweiten Halfte des 19. Jahrhunderts

    Science.gov (United States)

    Duerbeck, H. W.; Hansel, C.; Munzel, G.; Ilgauds, H.-J.; Borngen, M.

    2006-12-01

    The biography of the former member of the Saxonian Academy of Sciences, Carl Christian Bruhns, and appropiately published in their Transactions, originated from a series of lectures given some years ago. Gisela Munzel and Hans-Joachim Ilgauds, who have already written an authoritative history of Leipzig observatories, joined geophysicist Michael Borngen to describe various aspects of Bruhns' life and activities in different scientific fields. For the astronomical reader, Gisela Munzel's contribution is certainly the most rewarding one, and it covers almost the complete first half of the book. She not only describes Bruhns' astronomical career, but also supplies many details of his life. Having passed something equivalent to a junior high school, his father urged him to become apprentice in his own field, that of a locksmith. C.C. Bruhns became a mechanic in several companies in Berlin, and started also part-time work as a computer at Berlin Observatory in 1851. He soon was "discovered" by its director Johann Franz Encke, and became second assistant in mid-1852, first assistant in 1854 and observer in 1855. In mid-1856 he received his PhD on the topic of minor planets. A prize assignment on astronomical refraction developed into his habilitation thesis of 1859. When in 1857 the observer Heinrich d'Arrest left Leipzig Observatory, there were plans to replace him by an astronomer who would later also take over the post of the aging August Ferdinand Mobius. There were already plans to move the old Observatory on the tower of Pleissenburg castle to another location, when Bruhns was appointed observer and professor in April 1860. In Summer, construction of the new Observatory at Johannistal started, and it was inaugurated in late 1861. Munzel faithfully traces his work, his assistants and colleagues - Engelmann, Weinek, Zollner, and many more - , his activities in the founding of the Astronomische Gesellschaft, his work as a commissar of the ``Mitteleuropaische

  20. PREFACE: 15th International Conference on the Physics of Highly Charged Ions

    Science.gov (United States)

    Zou, Yaming; Hutton, Roger

    2011-07-01

    , under the Chairmanship of Professors Thomas Stoehlker and Joachim Ullrich. We wish them all the best with their plans and look forward to meeting you all again in 2012. Committees, Exhibitors and Sponsors HCI2010 International Advisory Committee F Aumayr (Austria) T Azuma (Japan) P Beiersdorfer (USA) J Burgdoerfer (Austria) A Cassimi (France) H Cederquist (Sweden) J Costello (Ireland) F Currell (UK) R Hoekstra (Holland) X Ma (China) F Martín (Spain) A Mueller (German) N Nakamura (Japan) M Pajek (Poland) R Rivarola (Argentina) Z Rudzikas (Lithuania) V Shabaev (Russia) R Schuch (Sweden) T Stoehlker (Germany) J Tanis (USA) L Tribedi (India) K Tokési (Hungary) J Ullrich (Germany) D Vernhet (France) Y Zou (China) T Zouros (Greece) HCI2010 Local Organizing Committee Co-chairs: Yaming Zou and Roger Hutton (Fudan university) Secretaries: Baoren Wei and Yunqing Fu (Fudan University) Treasurers: Xiuqing Xu and Daoli Xu (Shanghai Nuclear Society) Members Chongyang Chen (Shanghai) Jianmin Yuan (Changsha) Jun Yan (Beijing) Chenzhong Dong (Lanzhou) Xiaohong Cai (Lanzhou) Xinwen Ma (Lanzhou) Xuru Duan (Sichuan) Baohan Zhang (Sichuan) Exhibitors Andor Technology andor.com Shanghai Kelin Technology Development Co. Ltd chnkelin.com Varian Inc. varianinc.com Sponsors Natural Science Foundation of China International Union of Pure and Applied Physics (IUPAP) Fudan University

  1. Petrography, Mineral Chemistry and Geothermobarometry of Andalusite- Bearing Schists North of Azna (Northern Sanandaj-Sirjan Zone, Iran

    Directory of Open Access Journals (Sweden)

    Karim Abdollahi Silabi

    2016-07-01

    deformation that hasproduced the current morphologyof the Sanandaj-Sirjan zone (Shabanian Borujeni, 2008. In this paper we focused on petrography and mineral chemistry and thermodynamic conditions of the metapelites. Materials and methods The chemical compositions of minerals were determined by a CAMECA SX100 electron microprobe (EMP at Universität Stuttgart (Germany. The instrument is equipped with five wavelength dispersive spectrometers. The beam current and acceleration voltage were 15 nA and 15 kV, respectively. v Discussion and Results The Azna regional metamorphic rocks include quartz-feldspar schists, mica schists, andalusite-bearing schists and quartzites. The Azna metapelites are schists, containing quartz, feldspars, andalusite, muscovite, biotite, muscovite, chlorite and garnet, in variable proportions, characterized byporphyroblastic and lepidoblastic textures. Based on mineralogy, minerals of these rocks contain andalusite, garnet, feldspar, muscovite, biotite, quartz and chlorite. Microprobe analyses show that the mineral compositions are as follows: White micas in the andalusite-bearing schists are muscovite, plagioclases are albite-oligoclase, garnets are almandine-spessartine with weak chemical zoning and biotites are siderophylite-annite. Based on geothermobarometry, these rocks formed in the hornblende-hornfels facies and the low pressure part of the amphibolite facies,with temperatures about 562-692 °C and pressures1.07-4.12 kbar. After the regional metamorphism of these rocks,granitoidintrusions causedthermal metamorphism of these rocks and the formation of andalusite-bearing schists. Acknowledgments The authors wish to thank the Office of Graduate Studies of the University of Isfahan for their support. We also thank Prof. Hans-JoachimMassonne, who played major roles during the microprobe analysis of minerals at the InstitutfürMineralogie und Kristallchemie, Universität Stuttgart (Germany. References Aghanabati, A., 2004. Geology of Iran. Geological

  2. Submarines, spacecraft and exhaled breath.

    Science.gov (United States)

    Pleil, Joachim D; Hansel, Armin

    2012-03-01

    important concern is a suite of products from chemical reactions among oxidizing compounds with biological chemicals such as amines, thiols and carbonyls. SAMAP Meeting We (Armin and Joachim) attended the 2011 SAMAP conference in Taranto, Italy (10-14 October), which occurred just a few weeks after the IABR meeting in Parma, Italy (11-15 September 2011). It was held at the Officers' Club of the Taranto Naval Base under the patronage of the Italian navy; the local host was Lucio Ricciardi of the University of Insubria, Varese, Italy. At the 2011 SAMAP meeting, the theme was air-independent propulsion (AIP), meaning the capability of recharging the main batteries of the submarine without the need to surface. Only a few navies (e.g. US, UK, France, Russia, China) have historically had this capability using nuclear-powered submarines that can function underwater for extended periods of time (months). Most navies operate submarines with conventional diesel-electric propulsion, wherein diesel-powered generators charge battery banks which then drive an electric motor connected to the propeller. The batteries are charged while the boat is on the surface or during snorkelling, when the boat is submerged a few meters below the surface and a snorkel tube is extended to the surface. The period between battery charges can vary from several hours to one or two days depending on the power requirements and the nature of the mission. The process is necessary for breathing air revitalization (flushing out accumulated contaminants) and for the operation of the diesel engines. However, during this period the submarine is vulnerable to detection. Since the 1940s there have been various attempts to develop a power generation system that is independent of external air (AIP). To this end hydrogen peroxide was initially used and later liquid oxygen (LOX). Currently, most AIP submarines use fuel cell technology (LOX and hydrogen) to supplement the conventional diesel-electric system in order to

  3. Book Review: Beitraege zur Astronomiegeschichte, Band 5 (Acta Historica Astronomiae Vol. 15)

    Science.gov (United States)

    Duerbeck, H. W.; Dick, W. R.; Hamel, J.

    2002-12-01

    Pisa and the librarian Pozzetti at Bologna, and Karin Reich describes and edits Bessel's book critique of Gauss' Theoria Motus. How many one-time astronomers have to earn their living in other ways, become distracted from astronomical research, and vanish from the horizon of astronomical history? In the ninth paper, Hans-Joachim Ilgauds has traced the life of Georg Koch (1851-1905), who started his career as an astronomer at Leipzig Observatory in 1874. Later Koch worked at Hamburg Observatory, and then became an employee at the statistical office in Kiel, and finally director of the statistical office of the Hamburg revenue service. He was a collaborator for the statistical yearbook of German cities, and also contributed to a book investigating the causes and the impact of the cholera epidemic of 1892 in Hamburg. The last two papers deal with the circumstances of the discovery of the first Near-Earth asteroid (433) Eros. It was recorded on photographic plates taken at the Urania-Sternwarte Berlin and at Nice Observatory. The Berlin observer Witt announced the discovery, and only later, the Nice observer Charlois published a position of Eros. While all plates have disappeared, the authors Hans Scholl and Lutz D. Schmadel could prove that the Nice plate was poorly guided and Charlois would have been unable to discover the object. From a copy of the Berlin plate, published 50 years after the discovery by Witt's co-observer F. Linke, the exact position was determined, and the time of observation (which had not been published) was derived. The second article, by Lutz D. Schmadel, deals with the life of the Eros co-discoverer Felix Linke (1879-1959), who later worked in statistic offices, was a frequent writer of popular scientific articles, and later the editor of a journal, "Technik im Hotel'', and author of a book of the same title. As can be seen from the summaries given above, this collection of essays deals mainly with historical events that occurred in Germany and

  4. Obituary: Wulff-Dieter Heintz, 1930-2006

    Science.gov (United States)

    Augensen, Harry John; Geyer, Edward Heinrich

    2006-12-01

    ended, Wulff enrolled at Würzburg University, eventually completing his studies in 1950 with two majors, mathematics and chemistry. In 1950 he enrolled for graduate studies at Munich University. Conditions were horrid and austere, and the students were undernourished. Most of the university buildings had been destroyed during the war, but the buildings and domes of the Munich-Bogenhausen Observatory, which housed the meridian circles and the telescopes, suffered only minor damage. Lectures in astronomy were given in one of the small, surviving buildings on a tiny blackboard, forcing the lecturer to hold the chalk in his right hand and a sponge simultaneously in his left hand. Deplorable circumstances notwithstanding, Wulff, along with fellow classmates and future colleagues Edward Geyer, Theodor Schmidt-Kaler, and Joachim Herrmann, received a thorough instruction in astronomy from, among others, Hans Bucerius (celestial mechanics and theoretical astronomy), Wilhelm Rabe (binary stars), Erich Schoenberg (photometry, general astronomy), and Felix Schmeidler (astrophysics and galactic astronomy). Wulff also gained practical training in meridian circles and position micrometers, and learned to make binary star observations with the old Fraunhofer refractor (1835) of the Munich Observatory. It was here that his passion for binary stars was born. In 1953, Munich University awarded Wulff the degree of Doktor rerum naturalis in astronomy, which he completed under the direction of Felix Schmeidler. Wulff was almost immediately recruited by the Munich University Observatory to serve as the Scientific Assistant at the Southern Station in Mount Stromlo, Australia. He worked at Mount Stromlo from 1954 to 1955, then returned to Munich to serve as Research Officer from 1956-69, during which time he visited both the United Kingdom and the United States. Wulff was involved in observations of the planet Mars, and in particular the dust storms that were occurring on that planet around

  5. Psychopharmacology 2003 Conference, 10-13 September 2003

    Directory of Open Access Journals (Sweden)

    Diana P Morrison

    2003-09-01

    happens to my medical aid contribution? Eugene Allers 23. Financial issues in a modern private practice Mike Edwards 24. Transcranial magnetic stimulation: Uses in brain function research and medical intervention Alan St Clair Gibson 25. The Neurochemistry of dreams: Implications for Psychiatry Mark Solms 26. Tenascin-R expression in the Central Nervvous system of lower vertebrates Ruth Jarvis, N-. Hsu, P. Pesheva and D.M. Lang 25. Localisation of the Nogo-A receptor in Neronal Lipid rafts Edward Nyatia, D.M. Lang 26. Characterising an animal model for early life trauma using time dependent sensitisation Joachim D.K. Uys, Willie M.U. Daniels, Dan J. Stein 27. Tolmetin affords protection against Quinoclinic acid induced Neurotoxixity in Rat brain Amichand Dairam, S Daya 28. Acetaminophen and aspirin inhibit superoxide anion generation and Lipid Peroxidation, and protect against 1-Methyl-4Phenyl Pyridinim-induced Dopaminergic Neurotoxicity in rats H. Maharaj, D.S. Maharaj, K. S. Saravanan, K.P. Mohanakumar, S. Daya 29. Can exercise provide Neuroprotection in a rat model for Parkinson's disease? M Mabandla, L Kellaway, A St Clair Gibson, M Lambert, V Russell 30. Treatment of rapid cycling Bipolar disorder Joseph R. Calabrese 31. Depression as a Neurodegenerative Disorder: The need for achieving remission Roger M Pinder 32. Side-effects induced by modern antidepressants- Overview and management Franco Colin 33. The Placebo response in antidepressant clinical trials Robin Emsley 34. Impulse control disorders: An overview Donald W. Black 35. Post traumatic stress disorder: The Wits trauma clinic experience Ugash Subramaney 36. Post traumatic stress disorder among recently diagnosed patients with HIV in South Africa Soraya Seedat, Bo Olley, D J Stein 37. Improving outcome in Schizophrenia Diana P Morrison 38. Reviewing post Graduate training Cliff W Allwood 39. Ethics in HIV Research Keimanthro Moodley 40. Improving and maintaining ethical standrads in Psychiatric research

  6. EDITORIAL: Focus on Iron-Based Superconductors FOCUS ON IRON-BASED SUPERCONDUCTORS

    Science.gov (United States)

    Hosono, Hideo; Ren, Zhi-An

    2009-02-01

    Tegel, Inga Schellenberg, Falko M Schappacher, Rainer Pöttgen, Joachim Deisenhofer, Axel Günther, Florian Schrettle, Alois Loidl and Dirk Johrendt The superconductor KxSr1-xFe2As2: normal state and superconducting properties B Lv, M Gooch, B Lorenz, F Chen, A M Guloy and C W Chu Effect of 3d transition metal doping on the superconductivity in quaternary fluoroarsenide CaFeAsF Satoru Matsuishi, Yasunori Inoue, Takatoshi Nomura, Youichi Kamihara, Masahiro Hirano and Hideo Hosono Influence of the rare-earth element on the effects of the structural and magnetic phase transitions in CeFeAsO, PrFeAsO and NdFeAsO Michael A McGuire, Raphaël P Hermann, Athena S Sefat, Brian C Sales, Rongying Jin, David Mandrus, Fernande Grandjean and Gary J Long Heat capacity measurements on FeAs-based compounds: a thermodynamic probe of electronic and magnetic states P J Baker, S R Giblin, F L Pratt, R H Liu, G Wu, X H Chen, M J Pitcher, D R Parker, S J Clarke and S J Blundell Spin fluctuations, interband coupling and unconventional pairing in iron-based superconductors Zi-Jian Yao, Jian-Xin Li and Z D Wang Superconductivity induced by Ni doping in BaFe2As2 single crystals L J Li, Y K Luo, Q B Wang, H Chen, Z Ren, Q Tao, Y K Li, X Lin, M He, Z W Zhu, G H Cao and Z A Xu Metamagnetic transition in EuFe2As2 single crystals Shuai Jiang, Yongkang Luo, Zhi Ren, Zengwei Zhu, Cao Wang, Xiangfan Xu, Qian Tao, Guanghan Cao and Zhu'an Xu Pressure dependence of the thermoelectric power of the iron-based high-Tc superconductor SmFeAsO0.85 N Kang, P Auban-Senzier, C R Pasquier, Z A Ren, J Yang, G C Che and Z X Zhao Superconductivity in some heavy rare-earth iron arsenide REFeAsO1-δ (RE = Ho, Y, Dy and Tb) compounds Jie Yang, Xiao-Li Shen, Wei Lu, Wei Yi, Zheng-Cai Li, Zhi-An Ren, Guang-Can Che, Xiao-Li Dong, Li-Ling Sun, Fang Zhou and Zhong-Xian Zhao The delicate electronic and magnetic structure of the LaFePnO system (Pn = pnicogen) S Lebègue, Z P Yin and W E Pickett

  7. Flower symbolism and the cult of relics in medieval Serbia

    Directory of Open Access Journals (Sweden)

    Popović Danica

    2008-01-01

    deeds - devotion, fasting and prayer - and in particular from the ascetic way of life. The link between fragrance, flower symbolism and asceticism is a distinctive and very popular topos in Christian literature. It also has biblical models, such as, for example, Isaiah 35,1: 'The wilderness and the solitary place shall be glad for them; and desert shall rejoice, and blossom as the rose.' Exegetes interpreted the concept of the desert in a seemingly paradoxical way as anchoretic paradise and a place of plenty with a multitude of flowers in bloom - metaphor for monks and their virtues. The syntagm desertum floridus, therefore, has not only a strong internal logic, but also a precisely delineated field of meaning. Namely, the main goal of the desert fathers was to 'reconstruct' the Garden of Eden in their own living environments and thus anticipate the future heavenly gardens. The notions contained in the relic-related 'ideology' and practice of the Byzantine world elicited a creative response in the Balkans. The motif of flowers and their fragrance as a metaphor for paradise, triumph over death and rebirth in Christ was given its due place in the process of creating regional and national saintly cults. This may be seen from the texts written for the needs of the cults, such as, for exam-80 pie, the Life of St John of Rila, where the saint's relics are likened to a 'fragrant lily'. Particularly interesting for the subject here discussed is a description of the signs occurring at the grave of St Joachim of Osogov, because it provides a direct analogy with the miraculous uncovering of the relics of archbishop Eustathios. Namely, according to the hagiographer, at that very moment the earth above the grave rose up and the grave became surrounded with many a fragrant flower. In the Serbian environment such ideas can be traced back to the late twelfth and early thirteenth centuries or the time of St Sava and Stefan the First-Crowned, that is, the time of the establishment of the

  8. NARRATIVE: A short history of my life in science A short history of my life in science

    Science.gov (United States)

    Manson, Joseph R.

    2010-08-01

    beams of helium atoms from surfaces under clean high-vacuum conditions. This sabbatical was the beginning of a very fruitful and extremely pleasant collaboration working on a large variety of problems on the structure and dynamics of metal surfaces as elucidated by helium atom scattering, a collaboration that lasted until the retirements of Armand and Lapujoulade in the early 1990s. Nearly every summer and two additional sabbaticals in 1984 and 1992 were spent in this very stimulating research atmosphere located in the scientific complex on the southern edge of Paris. This period included collaborations and interactions with many of the colleagues, visitors and students at Saclay including C S Jayanthi, Abdelkader Kara, Luc Barbier, Hans-Joachim Ernst, Francoise Fabre and Bernard Salanon. Directly after this first sabbatical I spent a summer under the auspices of an Oak Ridge Associated Universities grant working with Rufus Ritchie in what was then the Health Sciences Division of the Oak Ridge National Laboratory (ORNL). Ritchie was a senior scientist at ORNL as well as a professor at the Physics Department of the University of Tennessee at nearby Knoxville. This one summer at ORNL also developed into a long and productive, as well as extremely pleasant, scientific collaboration with Ritchie that lasted into the 1990s. During the academic years at Clemson I was able to take off to ORNL for week-long periods several times a year. Our work involved calculating energy transfers in the interactions of electrons and other charged particles with surfaces, problems involving interactions of atomic and charged particles with surface plasmons and theories for developing interaction potentials between particles or between particles and surfaces. This work also had the great advantage of developing interactions and scientific collaborations with many others at ORNL, including Thomas Ferrell and Bruce Warmack. One of the advantages of being a scientist is the opportunity to travel

  9. Myxedematous cretinism with dwarfism or Spanish painting in doctor's collection and unforgettable French park

    Directory of Open Access Journals (Sweden)

    G A Melnichenko

    2010-12-01

    Full Text Available Долина королей, долина Луары – зачарованное место памятников истории и волшебных замков, удивительных садов и поразительных историй. В од- ном таком замке – Вилландри (http://www.chateauvillandry.fr/en неподалеку от Тура, переплелись французская история и история медицины. Своей нынешней славой замок обязан испанскому врачу Joachim Carvallo, родившемуся в Испании в 1869 г., прапрадедушке нынешнего владельца. Его медицинская карьера проходила в клинике профессора Charles Richet, нобелевского лауреата 1913 г. (работы по асфиксии, но после женитьбы он приобрел замок Вилландри, разместил там свою коллекцию испанской живописи и реализовал мечту о создании идеальных садов, жизни в гармонии с природой, среди посаженных человеком растений и деревьев в замке эпохи Ренессанса. Вероятно, контраст безмятежной красоты природы, и безупречной архитектуры, и трагического реализма испанских полотен был особенно важен доктору Корвалло, и среди его картин оказалась маленькая работа неизвестного автора, предположительно школы Гойи (рис.. Эта картина ранее не фигурировала, насколько мне известно, среди работ, о