WorldWideScience

Sample records for today ten year

  1. Chernobyl - ten years after

    International Nuclear Information System (INIS)

    1996-01-01

    This folder contains ten brief factsheets which aim to give a balanced presentation of the facts relating to the reactor accident at the Chernobyl power station ten years after the event. Details of the incident are given and its aftermath, in particular as it has affected the lives and health of people living in the immediate vicinity, is considered. Since records of the health of people in the region before the accident were very poor, it is extremely difficult to make definitive statements about the health effects of the accident. It is clear, however, that there has been a marked increase in the incidence of thyroid cancer especially among children in Belarus. Although curable this has given rise to deaths owing to poor health care. It is likely that deaths due to other cancers will occur in the longer term. Though estimates vary, they are in the region of 10-25,000 world wide over the next 70 years. Comparisons with the numbers of deaths from other large-scale non-nuclear industrial disasters are provided which put the Chernobyl incident in context and experts who refute the wilder claims made in the media are quoted. The status of the plant today and the international effort to improve the safety of the 15 original RMBK commercial reactors still operating in the former USSR are described. (Author)

  2. Affordances: Ten Years On

    Science.gov (United States)

    Brown, Jill P.; Stillman, Gloria

    2014-01-01

    Ten years ago the construct, affordance, was rising in prominence in scholarly literature. A proliferation of different uses and meanings was evident. Beginning with its origin in the work of Gibson, we traced its development and use in various scholarly fields. This paper revisits our original question with respect to its utility in mathematics…

  3. Ten Years of Chandra

    Science.gov (United States)

    Weisskopf, Martin C.

    2009-01-01

    We celebrated the 10-th anniversary of the Launch of the Chandra X-ray Observatory on July 13, 2009. During these 10 years data from this Great Observatory have had a profound impact on 21st century astrophysics. With its unrivaled capability to produce sub-arcsecond images, the Observatory has enabled astronomers to make new discoveries in topics as diverse as comets and cosmology. We shall review some of the highlights, discuss the current status, and future plans.

  4. ABACC ten years applying safeguards

    International Nuclear Information System (INIS)

    Palacios, Elias

    2001-01-01

    The Argentinian-Brazilian Agency for Accounting and Control of nuclear special materials has been in operations for ten years. The rational behind the creation and the work performed by the Agency during the last decade is described. (author)

  5. A Ten-Year Reflection

    Science.gov (United States)

    Phillip, Cyndi

    2016-01-01

    Five initiatives launched during Cyndi Phillip's term as American Association of School Librarians (AASL) President (2006-2007) continue to have an impact on school librarians ten years later. They include the rewriting of AASL's learning standards, introduction of the SKILLS Act, the presentation of the Crystal Apple Award to Scholastic Library…

  6. Ten Thousand Years of Solitude?

    International Nuclear Information System (INIS)

    Benford, G.; Pasqualetti, M.J.

    1991-03-01

    This report documents the authors work as an expert team advising the US Department of Energy on modes of inadvertent intrusion over the next 10,000 years into the Waste Isolation Pilot Project (WIPP) nuclear waste repository. Credible types of potential future accidental intrusion into the WIPP are estimated as a basis for creating warning markers to prevent inadvertent intrusion. A six-step process is used to structure possible scenarios for such intrusion, and it is concluded that the probability of inadvertent intrusion into the WIPP repository over the next ten thousand years lies between one and twenty-five percent. 3 figs., 5 tabs

  7. Ten Thousand Years of Solitude

    Energy Technology Data Exchange (ETDEWEB)

    Benford, G. (Los Alamos National Lab., NM (USA) California Univ., Irvine, CA (USA). Dept. of Physics); Kirkwood, C.W. (Los Alamos National Lab., NM (USA) Arizona State Univ., Tempe, AZ (USA). Coll. of Business Administration); Harry, O. (Los Alamos National Lab., NM (USA)); Pasqualetti, M.J. (Los Alamos National Lab., NM (USA) Arizona State Univ., Tempe, AZ (USA))

    1991-03-01

    This report documents the authors work as an expert team advising the US Department of Energy on modes of inadvertent intrusion over the next 10,000 years into the Waste Isolation Pilot Project (WIPP) nuclear waste repository. Credible types of potential future accidental intrusion into the WIPP are estimated as a basis for creating warning markers to prevent inadvertent intrusion. A six-step process is used to structure possible scenarios for such intrusion, and it is concluded that the probability of inadvertent intrusion into the WIPP repository over the next ten thousand years lies between one and twenty-five percent. 3 figs., 5 tabs.

  8. The Top Ten Websites in Critical Care Medicine Education Today.

    Science.gov (United States)

    Wolbrink, Traci A; Rubin, Lucy; Burns, Jeffrey P; Markovitz, Barry

    2018-01-01

    The number of websites for the critical care provider is rapidly growing, including websites that are part of the Free Open Access Med(ical ed)ucation (FOAM) movement. With this rapidly expanding number of websites, critical appraisal is needed to identify quality websites. The last major review of critical care websites was published in 2011, and thus a new review of the websites relevant to the critical care clinician is necessary. A new assessment tool for evaluating critical care medicine education websites, the Critical Care Medical Education Website Quality Evaluation Tool (CCMEWQET), was modified from existing tools. A PubMed and Startpage search from 2007 to 2017 was conducted to identify websites relevant to critical care medicine education. These websites were scored based on the CCMEWQET. Ninety-seven websites relevant for critical care medicine education were identified and scored, and the top ten websites were described in detail. Common types of resources available on these websites included blog posts, podcasts, videos, online journal clubs, and interactive components such as quizzes. Almost one quarter of websites (n = 22) classified themselves as FOAM websites. The top ten websites most often included an editorial process, high-quality and appropriately attributed graphics and multimedia, scored much higher for comprehensiveness and ease of access, and included opportunities for interactive learning. Many excellent online resources for critical care medicine education currently exist, and the number is likely to continue to increase. Opportunities for improvement in many websites include more active engagement of learners, upgrading navigation abilities, incorporating an editorial process, and providing appropriate attribution for graphics and media.

  9. Resolution 1540, ten years on

    International Nuclear Information System (INIS)

    Hautecouverture, Benjamin

    2014-06-01

    Adopted on the 28 April 2004 by the United Nations Security Council under Chapter VII of the UN Charter, Resolution 1540 is a composite tool that was hitherto unprecedented. To recap, States are bound to 'refrain from providing any form of support to non-State actors that attempt to develop, acquire, manufacture, possess, transport, transfer or use nuclear, chemical or biological weapons and their means of delivery' (par. 1), and to prohibit and prevent non-State actors from the aforementioned through 'appropriate and effective' (par. 2,3) legal, judiciary, and administrative means. A Committee was established to which States had to submit a first report outlining the steps 'they have taken or intend to take to implement this resolution' (par. 4). This Committee was initially established for two years and has been regularly renewed since, and its mandate was extended in 2011 for ten years. It is not a surveillance mechanism. Finally, with the aim of remedying difficulties that certain States may experience in implementing the Resolution, 'States in a position to do so' are invited to offer assistance (par. 7). The level of the application of Resolution 1540 was originally based on a delicate three-pronged balance of obligation, good will, and partnership. It is not a matter of designating certain States to the rest of the international community, whilst avoiding that the exercise be limited to the submission of national reports, instead aiming to initiate a dynamic. The wager was a risky one. Ten years on, 90% of UN member States have submitted one or several implementation reports. 170 States and 50 international and regional organisations have taken part in outreach and implementation support events. Whatever quantitative or qualitative conclusions that can be reached, we should continue to promote the Re-solution's universal adoption, and to ensure that the implementation of its provisions is undertaken in a lasting

  10. Ten years of effective multilateralism?

    International Nuclear Information System (INIS)

    Hautecouverture, Benjamin

    2013-12-01

    the following one: do the successes of multilateralism and international law provide security assurances or do they mask the flaws of an insufficiently intrusive system? While the U.S. signaled their defiance under the guidance of John Bolton, European thinking settled on a conclusion with the air of a slogan: yes to multilateralism, providing it is effective. This was to be the cornerstone of the policies to undertake and the instruments to implement to forge a global role for the Union. Its originality is based simultaneously in realism and in a refusal to resort to force as the foremost means of action on the international stage. Another way of defining the 2003 Strategy is a skillful compromise between differing positions to banish the Iraqi 'cacophony' as quickly as possible. Ten years on, it is now time for 'impact assessments' and other 'scorecards' of public policies. In the midst of the Eurozone economic crisis, evaluating a strategy of 'effective multilateralism' is not easy. The Union's bi-annual reports on its implementation have recently begun to try to provide a quantitative analysis that is not entirely convincing (for instance, the number of ratifications of such-and-such an instrument with regard to the budget allocated by the EU to facilitate its universalization, over such-and-such a period). Fundamentally, the 2003 Strategy is essentially beyond this kind of analysis even if it can prove useful. The strength of the European approach consists in establishing a long-term willingness to maintain and strengthen collective security tools approved by the greatest possible number of States. Its weakness is to occasionally confront a strategic reality that is as contradictory as it is stubborn. Effective multilateralism is linked to voluntarism and vows. (author)

  11. Ten Lessons from Ten Years PPP Experience in Belgium

    NARCIS (Netherlands)

    Willems, T.; Verhoest, K.; Voets, J.; Coppens, T.; van Dooren, W.; van den Hurk, M.

    2017-01-01

    In 2004 Flanders, the northern region of Belgium launched a range of large public–private partnership (PPP) projects for a total value of 6 billion euros. Ten years later, PPP has become a well-embedded procurement method for long-term public infrastructure projects. This article makes a critical

  12. Ten years after the Jali Commission

    African Journals Online (AJOL)

    Lukas Muntingh is an associate professor and co-founder and ... Ten years have lapsed since the Jali Commission's final report became publicly available, and ..... as is generally required across the public service. In 2010 the auditor general started to include performance targets in his audits, the results of which are not.

  13. Ten-year urban forestry action plan

    Science.gov (United States)

    J.W." Jerry" Van Sambeek

    2017-01-01

    The Ten-year Urban Forestry Action Plan: 2016-2026 was published in September, 2015 (see http://www.urbanforestry.subr.edu/FinalActionPlan_Complete_11_17_15.pdf). This 260 page heavily illustrated document was prepared by the National Urban and Community Forestry Advisory Council (NUCFAC) under leadership and funding from the USDA Forest Service. The Plan's...

  14. Czech, Slovak science ten years after split

    CERN Multimedia

    2003-01-01

    Ten years after the split of Czechoslovakia Czech and Slovak science are facing the same difficulties: shortage of money for research, poor salaries, obsolete equipment and brain drain, especially of the young, according to a feature in the Daily Lidove Noviny (1 page).

  15. School Psychologists' Job Satisfaction: Ten Years Later

    OpenAIRE

    Worrell, Travis G.

    2004-01-01

    School Psychologistsâ Job Satisfaction: Ten Years Later (ABSTRACT) This study was designed to replicate nationwide surveys completed in 1982 and 1992. The purpose was to examine and describe the levels of job satisfaction and the relationship between the variables in a national sample of school psychologists belonging to the National Association of School Psychologists (NASP). The sample for this study consisted of respondents who reported being full-time school practitioners. ...

  16. Ten Years of Speckle Interferometry at SOAR

    Science.gov (United States)

    Tokovinin, Andrei

    2018-03-01

    Since 2007, close binary and multiple stars are observed by speckle interferometry at the 4.1 m Southern Astrophysical Research (SOAR) telescope. The HRCam instrument, observing strategy and planning, data processing and calibration methods, developed and improved during ten years, are presented here in a concise way. Thousands of binary stars were measured with diffraction-limited resolution (29 mas at 540 nm wavelength) and a high accuracy reaching 1 mas; 200 new pairs or subsystems were discovered. To date, HRCam has performed over 11,000 observations with a high efficiency (up to 300 stars per night). An overview of the main results delivered by this instrument is given.

  17. Ten years of x-ray holography

    International Nuclear Information System (INIS)

    Faigel, G.; Bortel, G.; Tegze, M.; Fadley, C.S.; Simionovici, A.S.

    2007-01-01

    With the appearance of nano-science the role of local methods has become more and more important. Hard x-ray holography based on the inside reference point concept is a local probe of the atomic order in solids. It gives the 3D real space image of atoms without the phase ambiguity inherent to diffraction methods. In this paper a brief description of the basics of hard x-ray holography is given. The last ten years' experimental and evaluation-related developments are reviewed. We also introduce different variants of the method, such as Bremsstrahlung and gamma ray holography (GRH). The power of the method is illustrated by examples. We outline new directions and future possibilities. (authors)

  18. Virgin galactic the first ten years

    CERN Document Server

    Seedhouse, Erik

    2015-01-01

    Thirty years ago when Sir Richard Branson called up Boeing and asked if they had a spare 747, few would have predicted the brash entrepreneur would so radically transform the placid business of air travel. But today, Branson flies airlines on six continents, employs hundreds of jets and, in 2014, was predicting that his spaceship company – Virgin Galactic – would soon open the space frontier to commercial astronauts, payload specialists, scientists and space tourists. With more than 600 seats sold at $250,000 each, what started off as a dream to send people just for the excitement to look back and marvel at Earth, was on the cusp of finally being turned into a business. Then, on October 21, 2014, tragedy struck. SpaceShipTwo was on its most ambitious test flight to date. Seconds after firing its engine, Virgin Galactic’s spaceship was breaking through the sound barrier. In just the three seconds that it took for the vehicle to climb from Mach 0.94 to Mach 1.02, co-pilot Mike Alsbury made what many close...

  19. Choledochal cysts: our ten year experience.

    LENUS (Irish Health Repository)

    Cianci, F

    2012-04-01

    We present our experience in the management of choledochal cysts from 1999 to 2009. A retrospective review of all charts with a diagnosis of choledochal cysts in our institution in this ten-year period. Data was collated using Excel. A total of 17 patients were diagnosed with choledochal cyst: 9 females and 8 males. The average age at diagnosis was 28 months (range from 0 to 9 years). The most common presenting symptoms were obstructive jaundice 6 (35%) and abdominal pain and vomiting 4 (23%). Ultrasound (US) was the initial diagnostic test in all cases with 4 patients requiring further investigations. All patients underwent Roux-en-Y Hepaticojejunostomy. The average length of stay was 11 days. Patients were followed up with Liver Function Tests (LFTS) and US 4-6 weeks post-operatively. Three patients developed complications including post-op collection, high drain output requiring blood transfusion and adhesive bowel obstruction. Our overall experience with choledochal cyst patients has been a positive one with effective management and low complication rates.

  20. Ten years of energy policy in Catalonia

    International Nuclear Information System (INIS)

    Masalles Roman, I.; Marin Sanchez, J.M.; Gurgui Ferrer, A.; Figuerola Perez, E.

    1992-01-01

    Catalonia is located in the north-east corner of Spain, on the Mediterranean coast and bordering with France in the north. It is one of the most industrialized and developed regions of Spain, with a per capita income of 10879 ECU per year (1989), 21.9% higher than the Spanish average. It contributes to 20.3% of the Spanish GDP. Primary energy consumption was 16.5 M toe in 1989, covered by the following sources: 3.5% coal, 51.8% oil, 9.4% natural gas, 3.6% hydro, 30.8% nuclear, 0.1% electrical import/export balance and 0.8% waste residuals. Oil dependence is distorted by the existence of a major petrochemical industry that uses more than 2.6 Mtoe of oil derivatives for non-energy purposes. Final energy demand in 1989 was 8.8 Mtoe, 40.9% for industry, 36.9% for transportation and 22.3% for the domestic and services sector. In the 60's, Catalonia's socio-economic development was accompanied by a spectacular increase in the demand for primary energy: from slightly above 2.5 million toe in 1960 to 5.6 Mtoe ten years later. If this decade can be characterized by a steady increase in the total value of consumption, the 70's also constitute years of major changes in the field of energy on an international scale (the oil crisis) and in politics in the Spanish State. 6 refs., 3 figs., 6 tabs

  1. Ten years for the public Web

    CERN Multimedia

    2003-01-01

    Ten years ago, CERN issued a statement declaring that a little known piece of software called the World Wide Web was in the public domain. Nowadays, the Web is an indispensable part of modern communications. The idea for the Web goes back to March 1989 when CERN Computer scientist Tim Berners-Lee wrote a proposal for a 'Distributed Information Management System' for the high-energy physics community. The Web was originaly conceived and developed to meet the demand for information sharing between scientists working all over the world. There were many obstacles in the 1980s to the effective exchange of information. There was, for example a great variety of computer and network systems, with hardly any common features. The main purpose of the web was to allow scientists to access information from any source in a consistent and simple way. By Christmas 1990, Berners-Lee's idea had become the World Wide Web, with its first server and browser running at CERN. Through 1991, the Web spread to other particle physics ...

  2. The origin of the future ten questions for the next ten years

    CERN Document Server

    Gribbin, John

    2006-01-01

    How did the universe begin? Where do galaxies come from? How do stars and planets form? Where do the material particles we are made of come from? How did life begin? Today we have only provisional answers to such questions. But scientific progress will improve these answers dramatically over the next ten years, predicts John Gribbin in this riveting book. He focuses on what we know—or think we know—about ten controversial, unanswered issues in the physical sciences and explains how current cutting-edge research may yield solutions in the very near future. With his trademark facility for engaging readers with or without a scientific background, the author explores ideas concerning the creation of the universe, the possibility of other forms of life, and the fate of the expanding cosmos. He examines “theories of everything,” including grand unified theories and string theory, and he discusses the Big Bang theory, the origin of structure and patterns of matter in the galaxies, and dark mass and dark ene...

  3. Ten Years of Tamoxifen Reduces Breast Cancer Recurrences, Improves Survival

    Science.gov (United States)

    ... of Breast & Gynecologic Cancers Breast Cancer Screening Research Ten Years of Tamoxifen Reduces Breast Cancer Recurrences, Improves ... a link to this page included, e.g., “Ten Years of Tamoxifen Reduces Breast Cancer Recurrences, Improves ...

  4. Spacelab - Ten years of international cooperation

    Science.gov (United States)

    Bignier, M.; Harrington, J. C.; Sander, M. J.

    1983-01-01

    The history, current status, and future plans of the Spacelab program are reviewed, with a focus on the cooperative relationship between ESA and NASA. The initial decision to undertake the program and the three agreements signed to begin its implementation are examined, and the division of responsibilities and financial contributions is discussed insofar as it affected the management structure. Consideration is given to the major facilities, the 50-mission operational cycle, communications, the currently scheduled activities (through 1985), the prospective later uses, and the ten dedicated discipline laboratories. The importance of continuous mutual support during the planning and development phases is stressed. The program so far is considered a success, in terms of the goals set by the participants and in terms of the resolution of the problems inherent in international technological endeavors.

  5. Ten years of predictions ... and counting.

    Science.gov (United States)

    Cozzetto, Domenico; Di Matteo, Adele; Tramontano, Anna

    2005-02-01

    The CASP experiment has been run every other year since 1994. Its objective is to subject the available structure prediction methods to a blind test. This is a short report of the highlights of its last edition. 'Men who wish to know about the world must learn about it in its particular details' (Heraclitus of Ephesus, 535-475 bc).

  6. Ten years of SLR production in Argentina

    Science.gov (United States)

    Pacheco, A.; Podestá, R.; Yin, Z.; Liu, W.; Actis, E.; Adarvez, S.; Quinteros, J.; Podestá, F.

    2017-07-01

    SLR technique is a proved astro-geodetic art with a significant power to contribute to Earth and Space Sciences. Therefore, scientific applications of SLR System are able to perform multiple tasks in the fields of Astrometry, Geodesy and Geophysics. The results we show here were obtained from satellite observations made at SLR 7406 Station of Observatorio Astronómico Félix Aguilar (OAFA) in San Juan, Argentina. The telescope was installed early on 2006, in concordance with an International Cooperation Agreement between Universidad Nacional de San Juan, Argentina and Chinese Academy of Sciences. In this abstract we show the current research being done with ILRS 7406 station: Length of day (LOD) and Angular velocity of Earth Rotation, calculated weekly; Pole Motion. ILRS7406 is daily surveying Pole coordinates x and y; Tracking SLR to GNSS constellations. SLR System contributes to the adjustment and validation of satellite GALILEO, GPS, GLONASS, and BEIDOU orbits. Our station is nowadays member of the new ITRF 2014 frame, and these past years has been one of the 3 highest producing SLR Stations on the ILRS net, composed of about 40 stations distributed all around the world. The obtained results during this first 10 years of experience are useful to enhance the traditional collaboration between OAFA and international services such as ILRS, IERS and NASA.

  7. Ten years of Brazilian ballast water management

    Science.gov (United States)

    Castro, Maria Cecilia Trindade; Hall-Spencer, Jason M.; Poggian, Cecília Fonseca; Fileman, Timothy W.

    2018-03-01

    In 2005, Brazil addressed the environmental challenges posed by ballast water through a unilateral regulation, called the Maritime Standard N° 20 (NORMAM-20), applied to all shipping in her waters. This world-leading decision was the culmination of a process that started during the 1990‧s. Here, we summarize how these ballast water regulations were brought in and adopted and present the findings of 10 years of enforcement (2005-2015) in 39 ports along the Brazilian coast. We show that compliance with the Brazilian standard has increased significantly since the regulations were implemented (p < 0.001). After five years of implementation, non-compliance decreased probably reflecting an increase in awareness of the Brazilian Standard and a shift in the shipping industry commitment to minimize and control the spread of invasive species through ballast water. The Brazilian experience shows that very high levels (97%) of compliance with ballast water management regulations can be made to work in a region of global importance to the maritime industry. In the last decade, the rules governing ballast water in Brazil have evolved to address the demands from the maritime community and to provide updates such as imminent requirements for the use of ballast water management systems on board ships. These regulations are rarely cited when ballast water regulations are discussed internationally, yet there is much to learn from the proactive approach taken by Brazil such as what is feasible and enforceable.

  8. Ten years of CR physics with PAMELA

    Science.gov (United States)

    Galper, A.; Spillantini, P.

    2017-09-01

    The satellite borne Pamela instrument is dedicated to the precise and high statistics study of CR fluxes on a four decades energy range. Pamela experiment is the last step of the "Russian-Italian Mission" (RIM) program established in 1992 between several Italian and Russian institutes and with the participation of Sweden and Germany. Designed as a cosmic ray observatory at 1 AU, it extensive program is made possible thanks to the outstanding performance of the instrument, the low energy threshold, the quasi-polar orbit and the 10 years duration of the observation. The physics program pays particular attention to the study of particles and antiparticles fluxes and includes search for dark matter, primordial antimatter, new matter in the Universe, study of cosmic-ray propagation, solar physics and solar modulation, and terrestrial magnetosphere. Very important is the discovery of the anomalous increase of the positron flux at energies higher that 50 GeV (the so called "Pamela anomaly"), and the abrupt spectral hardening of H and He, challenging the current paradigm of cosmic-ray acceleration and propagation in the Galaxy.

  9. Ten years in a golden cage

    International Nuclear Information System (INIS)

    Riehl, N.

    1988-01-01

    The book presents the personal experiences of the author who spent the years from 1945 to 1955 in post-war Russia as head of a group of German scientists and engineers. Due to his perfect command of the Russian language and the significance of his professional position, he was able to get a closer insight into the life in the Soviet Union than foreigners usually have the chance to. The author met people on government level, in the ministerial administration, in research establishments and factories, and in everyday life. He tells about the deportation to the Soviet Union in 1945, the difficulties in finding a suitable site for the uranium laboratories and in starting work, and about the successful work of the group, first in Elektrostal near Moscow and later in Sungul in the Urals (1950-1952). He tells about their struggle for a return to Germany which finally came true in 1955. His report is full of interesting details about the secrecy regime, planned economy, training of Soviet scientists and experts, the situation of the group of German experts and their behaviour, the living standard and political life in the Soviet Union, the Lyssenko affair. The author's impression is that the deeply solidified structures of state capitalism will not permit a profound change of the economic system in the Soviet Union, but trends towards liberalisation are detectable. (orig./HSCH) [de

  10. Power and energy balances, today and three years ahead

    International Nuclear Information System (INIS)

    Borg, Trygve; Maula, H.; Pedersen, Jens; Soendergren, C.; Waegelund, G.; Granlund, K.

    2003-06-01

    Energy scenario 2006: In normal conditions the Nordel system is balancing well. It is expected that the Nordel system will cope with a single dry year situation. if a year with extreme low hydropower production or a combination of two dry years in succession occurs, the result may be a very serious balance deficit. For part of the Nordel system it is possible that market cannot solve the problem and the situation will demand various forms of rationing or other measures. Power balance winter peak demand 2006/07: During a normal winter, peak demand will be handled without difficulties. If a ten years winter occurs the power balance is expected to come under strain and the Nordic power system is dependent on import from Europe via strong interconnections. The forecast shows that there probably is enough production capacity and import possibilities from countries outside Nordel. (BA)

  11. Managing mountain hardwoods - a ten-year appraisal

    Science.gov (United States)

    George R., Jr. Trimble

    1961-01-01

    Ten years ago - in 1949 - four 5-acre plots were established on the Fernow Experimental Forest near Parsons, West Virginia, to show the effects upon mountain hardwoods of each of four management treatments.

  12. Analysis of ten years production trends of a Nigerian University ...

    African Journals Online (AJOL)

    The annual feed allowances of the pigs were far below the annual feed requirements in quantitative and qualitative terms over the ten-year period. The highest feed consumption deficit was recorded in the 10th year and the least deficit in the first year. Because of continued increase in the cost of feeds coupled with ...

  13. The State of the Carbon Cycle: Ten Years On

    Science.gov (United States)

    King, A. W.; Dilling, L.; Fairman, D. M.; Houghton, R. A.; Marland, G.; Rose, A.; Wilbanks, T. J.; Zimmerman, G.

    2015-12-01

    It has been nearly ten years since the First State of the Carbon Cycle Report (SOCCR-1) was published in 2007. Much has changed in the intervening years, but much has remained the same. In anticipation of a Second State of the Carbon Cycle Report (SOCCR-2), we, the members of the SOCCR-1 Coordinating Team, felt that a perspective from the first SOCCR and reflection on changes in the state of carbon cycle science and policy in the intervening years would be appropriate. The purpose of SOCCR-1 was to provide "…a synthesis and integration of the current knowledge of the North American carbon budget and its context within the global carbon cycle [i]n a format useful to decision makers." Being "useful to decision makers" was a guiding theme with three stakeholder workshops an integral part of the process. Drafting and revision of SOCCR-1 took place between 2005 and early 2007; the report's carbon budget was for circa 2003. In 2003, North America's fossil-fuel CO2 emissions were approximately 27% of global emissions. Nearly 85% of North American emissions were from the US, still at that time the world's largest emitter of fossil-fuel CO2. China's annual CO2 emissions exceeded those of the US for the first time while SOCCR-1 was being written. Today global CO2 emissions are dominated by emissions from China (28% in 2013), with US emissions only 14% of global emissions. Emissions from the US and North America have actually declined by approximately 10% since 2003 while emissions from China have doubled. Based on inventories of terrestrial carbon stocks, SOCCR-1 estimated that circa 2003 North American vegetation removed and stored a net 500 Mt C y-1 (±50%) from the atmosphere. A more recent synthesis incorporating additional estimates from atmospheric inversions and terrestrial biosphere modeling estimated the North American land sink for the decade of 2000-2009 at 350-470 Mt C y-1, with a slightly greater uncertainty due to the wider range of estimates from the

  14. Closer to zero: Reflections on ten years of ART rollout

    African Journals Online (AJOL)

    To reflect upon ten years of antiretroviral therapy. (ART) rollout, one really should set the clock back a little further to see the massive impact of ART on our lives – for clinicians and patients alike. My own journey with HIV began in 1999 when, as a young doctor, I decided to venture into private practice with a local general ...

  15. Ten-year-olds' reflections on their life in preschool

    DEFF Research Database (Denmark)

    Broström, Stig

    2016-01-01

    What do children think of their time in preschool? In the present study, twelve ten-year-old children collected data from their classmates. The children tend to remember their friends, and reflect on what games they played and with whom. Only about one in three respondents even mentioned the day...

  16. Ten years into the marshes – Hapalemur alaotrensis conservation ...

    African Journals Online (AJOL)

    Natural resource management problems typically involve a multitude of stakeholders with diverse sets of needs and interests, and often conflicting worldviews in an ... during the past ten years at Lake Alaotra, discussing the plan of action and challenges for environmental education, ecotourism and alternative livelihoods.

  17. Ten years of PPP in Belgium: an overview

    NARCIS (Netherlands)

    van den Hurk, M.; van Garsse, S.; Verhoest, K.

    2015-01-01

    It has been more than ten years since Public-Private Partnership [ppp] began a strong revival in Belgium. On the brink of the 21st century, one could notice the first indications in that direction. As of 2013, ppp has developed into a well-embedded method for numerous infrastructure projects.

  18. Eight to ten years follow-up after carotid endarterectomy

    DEFF Research Database (Denmark)

    Knudsen Rathenborg, Lisbet; Sillesen, H; Schroeder, T

    1990-01-01

    Follow-up information was obtained on 185 patients who consecutively underwent carotid endarterectomy eight to ten years previously. Doppler ultrasound examination was performed in 59 patients who were still alive and living within 100 miles of the hospital. Using lifetable analysis, the annual r...

  19. Changes in users' Web search performance after ten years ...

    African Journals Online (AJOL)

    The changes in users' Web search performance using search engines over ten years was investigated in this study. Matched data obtained from samples in 2000 and 2010 were used for the comparative analysis. The patterns of Web search engine use suggested a dominance in using a particular search engine. Statistical ...

  20. Threat Barometer. Ten Years of Terrorist Threat Assessment Netherlands

    NARCIS (Netherlands)

    Bakker, E.; Roy, de van Zuijdewijn J.

    2015-01-01

    In this essay, which was commissioned by the NCTV to mark the occasion of the conference “Threat Barometer. Ten years of Terrorist Threat Assessments for the Netherlands 2005-2015”, we address this and other aspects of the DTN and consider how this instrument has developed over the past decade. We

  1. Ten-year scheme of network development - 2011

    International Nuclear Information System (INIS)

    2011-01-01

    RTE, an independent subsidiary of EDF, is the French electricity transmission system operator. It is a public service company responsible for operating, maintaining and developing the high and extra high voltage network. It guarantees the reliability and proper operation of the power network. RTE transports electricity between electricity suppliers (French and European) and consumers, whether they are electricity distributors or industrial consumers directly connected to the transmission system. The mission of RTE is to balance the electricity supply and demand in real time. With the support of the government authorities, RTE prepares a ten-year scheme of network development in France; This document presents the main electricity transport infrastructures to foresee within the ten coming years and lists the network development investments which must be realised and implemented within 3 years. The document is updated each year and comes to complement at the national level the European ten year network development plan (TYNDP) and the European regional plans as provided for in the 2009/72/CE European directive

  2. Ten-year scheme of network development - 2013 edition

    International Nuclear Information System (INIS)

    2013-01-01

    RTE, an independent subsidiary of EDF, is the French electricity transmission system operator. It is a public service company responsible for operating, maintaining and developing the high and extra high voltage network. It guarantees the reliability and proper operation of the power network. RTE transports electricity between electricity suppliers (French and European) and consumers, whether they are electricity distributors or industrial consumers directly connected to the transmission system. The mission of RTE is to balance the electricity supply and demand in real time. With the support of the government authorities, RTE prepares a ten-year scheme of network development in France; This document presents the main electricity transport infrastructures to foresee within the ten coming years and lists the network development investments which must be realised and implemented within 3 years. The document is updated each year and comes to complement at the national level the European ten year network development plan (TYNDP) and the European regional plans as provided for in the 2009/72/CE European directive

  3. Assisted reproductive technologies in South Dakota: the first ten years.

    Science.gov (United States)

    Brannian, John; Hansen, Keith

    2006-07-01

    One in six couples experience infertility. New assisted reproductive technologies such as in vitro fertilization (IVF) have helped thousands of couples worldwide to have a family. IVF has been available in South Dakota for the past ten years. Improvements in the clinic and laboratory have led to better live birth rates and lower incidences of multiple pregnancies. Advances in technology will help even more people overcome fertility problems in the near future.

  4. Ten years campaign of Economical Heating: Successfull and educative

    International Nuclear Information System (INIS)

    Van den Brink, L.J.

    1992-01-01

    A review is given of the origin, the evolution and the results of the title campaign held by the natural gas and energy distribution companies in the Netherlands during the last ten years. The campaign is discussed against the background of the unique position of natural gas in the Netherlands within the context of the environmental protection activities of the energy distribution companies. 1 fig., 5 ills., 9 tabs

  5. Moving Upstream and Going Local: The Responsibility to Protect Ten Years Later

    Directory of Open Access Journals (Sweden)

    Bridget Moix

    2015-10-01

    Full Text Available Ten years ago the international community pledged to protect civilians from genocide, ethnic cleansing, war crimes, and crimes against humanity by endorsing the responsibility to protect (R2P doctrine. Yet today, horrific violence against civilians continues in places like Syria, Iraq, and South Sudan. This article examines some of the progress and gaps in the international community’s efforts to better protect civilians against mass violence over the past decade. It proposes two emerging directions for advancing the R2P agenda in the coming years: 1 greater focus on upstream prevention, and 2 increased support for locally-led peacebuilding and prevention actors and capacities.

  6. Elliot Lake uranium mine reclamation, the first ten years

    International Nuclear Information System (INIS)

    Payne, R.A.

    2000-01-01

    In 1989, Rio Algom Limited finalized its plans for the closure and subsequent decommissioning of two of its then three operating mines in Elliot Lake as a result of market conditions. These two mines closed in August 1990. These mine closures had significant impacts. The principal mining operations of Rio Algom at that time were still in Elliot Lake and had been the very foundation of the company for about 40 years. The business impact on the Corporation was regarded as possibly severe. The resultant layoff of over 1,500 long-term, highly qualified, skilled and well-paid employees, a devastating blow to the affected employees and their families, would have a significant financial impact on the municipal economy, particularly as this announcement was seen as the first step in the early closure of all four operating mines in the region. At that time there was little precedence for such a high profile mine closure program and consequently the many unknowns relating to the mine decommissioning process, legislative requirements and society's expectations resulted in a perception of a significant yet ill-defined liability. In this atmosphere of understandable company, stakeholder and public concern, Rio Algom Limited embarked on what has turned out to be a long, rigorous, challenging yet ultimately reasonable and rewarding process of progressive reclamation of all its Elliot Lake mines, some ten in total (nine uranium, one copper). Over the past ten years, reclamation of all ten mines has been successfully completed, some $70 m plus has been expended in direct site reclamation works and the workforce has been reduced from over 2,500 to just 4. After ten years, the focus of attention is now on the long-term care, maintenance, monitoring and reporting required for the decommissioned mine sites, and the accomplishment of this in the best interests of all the stakeholders. (author)

  7. The next ten years in neonatology: new directions in research

    Directory of Open Access Journals (Sweden)

    Vassilios Fanos

    2014-06-01

    Full Text Available This paper is a prelude to proceedings of the 10th International Workshop on Neonatology to be held in Cagliari, Italy from October 21st to 25th, 2014. These proceedings will be a significant milestone, highlighting the new frontiers of perinatal and neonatal research. Over the five days of this meeting, we aim to (1 examine the roots of the new directions in perinatal and neonatal research; (2 predict the trajectories of advancement in medical technologies, research, clinical care and teaching that will be the future of perinatology and neonatology. The discussion will be in four sections:back to the future: the placenta and perinatal programming;paradigm shift: the revolution of metabolomics in perinatalogy and neonatology;brave new world: the microbiome and microbiomics from perinatal to adult life;new inhabitants on the planet earth: adults who were born with extremely low birth weight. Proceedings of the 10th International Workshop on Neonatology · Cagliari (Italy · October 22nd-25th, 2014 · The last ten years, the next ten years in Neonatology Guest Editors: Vassilios Fanos, Michele Mussap, Gavino Faa, Apostolos Papageorgiou

  8. [Omalizumab: What have we learned after ten years of prescription?].

    Science.gov (United States)

    Pradère, P; Garcia, G; Humbert, M; Aubier, M; Taillé, C

    2016-02-01

    Omalizumab, an anti-immunoglobulin E monoclonal antibody, has now been used for ten years as an add-on therapy for severe adult atopic asthma, poorly controlled by high-doses inhaled steroids and long-acting beta-agonists. This innovative therapy has been the first biotherapy used on a large scale in severe asthma. It has shown clinical benefits, especially in the prevention of severe exacerbation, with a satisfactory safety profile. Despite its cost, it is an interesting alternative to continuous oral steroids, which cause more long-term side effects. After ten-years of prescription of omalizumab, we review here the mechanism of action, the benefits, the main side effects, the cost-effectiveness and also the alternative indications of this interesting molecule. We also consider the practicalities of using omalizumab, particularly the importance a rigorous assessment of its efficacy after 16 weeks of treatment, and possible future therapeutic indications. Omalizumab has proven its efficacy in large randomized studies but also in real life practice in severe allergic asthma. Copyright © 2015 SPLF. Published by Elsevier Masson SAS. All rights reserved.

  9. Ten Years of Support for Basic Scientific Research by CONACYT

    Directory of Open Access Journals (Sweden)

    Luis Humberto Fabila Castillo

    2014-01-01

    Full Text Available This paper reviews the results of ten years of support for basic scientific research by the CONACYT. The paper identifies the strongest areas of knowledge in basic science in Mexico and concludes that the institutions where basic science is done are mainly public higher education institutions, followed by also public research centers, while private institutions of higher education and companies carry out almost no research in basic science. Findings show that research on basic science in state universities has grown impressively in recent years, reaching the level of the institutions of higher education of the Federal District. Finally, the implications of these findings as well as the public policies through which support has been granted are discussed.

  10. Results in Assisted Peritoneal Dialysis: A Ten-Year Experience

    Directory of Open Access Journals (Sweden)

    Sara Querido

    2015-01-01

    Full Text Available Background/Aims. Peritoneal dialysis is a successful renal replacement therapy (RRT for old and dependent patients. We evaluated the clinical outcomes of an assisted peritoneal dialysis (aPD program developed in a Portuguese center. Methods. Retrospective study based on 200 adult incident patients admitted during ten years to a PD program. We included all 17 patients who were under aPD and analysed various parameters, including complications with the technique, hospitalizations, and patient and technique survival. Results. The global peritonitis rate was lower in helped than in nonhelped patients: 0.4 versus 0.59 episodes/patient/year. The global hospitalization rate was higher in helped than in nonhelped patients: 0.67 versus 0.45 episodes/patient/year (p=NS. Technique survival in helped patients versus nonhelped patients was 92.3%, 92.3%, 83.1%, and 72.7% versus 91.9%, 81.7%, and 72.1%, and 68.3%, at 1, 2, 3, and 4 years, respectively (p=NS, and patient survival in helped patients versus nonhelped patients was 93.3%, 93.3%, 93.3%, and 74.7% versus 95.9% 93.7%, 89%, and 82% at 1, 2, 3, and 4 years, respectively (p=NS. Conclusions. aPD offers an opportune, reliable, and effective home care alternative for patients with no other RRT options.

  11. Rejuvenating immunity: ?anti-aging drug today? eight years later

    OpenAIRE

    Blagosklonny, Mikhail V.

    2015-01-01

    The 2014 year ended with celebration: Everolimus, a rapamycin analog, was shown to improve immunity in old humans, heralding ?a turning point? in research and new era in human quest for immortality. Yet, this turning point was predicted a decade ago. But what will cause human death, when aging will be abolished?

  12. The General Factor of Personality: Ten Years After

    Directory of Open Access Journals (Sweden)

    Janek Musek

    2017-05-01

    Full Text Available According to the empirical and theoretical research in past ten years, the General Factor of Personality (GFP was interpreted as the highest-order (most general personality dimension, which occupies the apex of the structural hierarchy of personality traits. Thus, the GFP is the central concept in the new structural paradigm of personality (the Pyramidal Model of Personality. In the majority of the studies, the GFP was conceptualized as a general factor with substantial psychological (cognitive and behavioural content reflecting the general social and personal adjustment or effectiveness. The alternative explanations of the GFP emphasize the role of the semantic factors, response styles and other biases. This study reviews the main results of the GFP research including the nature, the biological bases, the strength and cultural universality of GFP, its relations to intelligence and other prominent psychological variables, and its predictive power and practical importance.

  13. Ten years of the uranium mines at Hamr na Jezere

    International Nuclear Information System (INIS)

    Stehlik, J.

    1976-01-01

    The ten-year long history of the uranium mine at Hamr na Jezere near Ceska Lipa (Czechoslovakia) is briefly discussed. The deposit is of the sedimentary-epigenetic origin and is located in complex hydrogeologic conditions in the so-called Lusatian Cretaceous system in the Bohemian Cretaceous Plateau. The deposit is characteristic of a considerable proportion of zirconium which forms complex minerals with uranium. The ore is exploited using two mining procedures. In areas with favourable geologic and hydrogeologic conditions it is the conventional mining method, in other parts chemical in-situ leaching is employed. The main demands placed on the two mining technologies include the undisturbed Turonian drinking water aquifer, minimum intrusion into the landscape and the treatment of radioactive waters before discharge into public water supplies. The importance of the Hamr deposit and the further development of the Uranium Mines Concern are indicated. (B.S.)

  14. The Chooz power station: ten years of operation

    International Nuclear Information System (INIS)

    Teste du Bailler, Andre

    1977-01-01

    The switching into actual service of the Chooz plant, the first pressurized water reactor ever built in France, occurred on 3rd april 1967. Ten years later, one can establish a highly positive balance schedule of plant's operation whose availability is satisfactory, except the mechanical failure which occurred during the startup. The behavior of the equipment, in particular of the components of the primary loop, was satisfactory in its whole since it allowed the gradual increase in capacity by 15% with respect to the initial design. It allowed also the achievment of noticeable progress in the design of equipment intended for the new power stations. Interesting results have also been obtained in radioprotection, working conditions of the staff and environment protection fields. Finally, the training of the operating teams has been closely followed, whether it concerned the operators directly affected by plant operation or the trainees gathered in a school specially organized for this purpose and transferred since to a training Center [fr

  15. Ten years of energy consumption in the tertiary sector

    International Nuclear Information System (INIS)

    Rabai, Yacine

    2012-11-01

    This document presents and comments data regarding electricity consumption by the tertiary sector over the last ten years in France. It notably outlines its strong increase compared to the other sectors (housing, industry, transport, agriculture). It comments the evolution of the energy mix of the tertiary sector (electricity with 47%, gas with 25% and oil with 19% are prevailing). It briefly comments the evolution of energy efficiency within this sector. It indicates and comments the shares of energy consumption, of high voltage electricity and gas consumption by the different sub-sectors (retail, automobile and motorcycle repair, public administration, health and social activity, real estate, specialised, scientific and technical activities, education, and so on)

  16. Ten-Year Network Development Plan - 2015 edition, executive summary

    International Nuclear Information System (INIS)

    2016-01-01

    Complying with the European and French laws, each year, RTE prepares and publicizes a Ten-Year Network Development Plan (NDP) to meet the expectations of its stakeholders and customers. The NDP lists the network development projects that RTE plans to complete and commission over a 3-year period and presents the main power transmission infrastructure work envisaged for the next Ten-years. Beyond, it outlines the possible network adaptation needs for a variety of energy transition scenarios. Over the next 10 years, the network investments will make it possible to: - Meet the goals of the Regional Climate Air Energy Plans, - Create 4 GW of extra offshore wind generation integration capacity and 10 GW of additional interconnection capacity, 2/3 more than the current capacity, - Enable the development of economically and demographically dynamic areas, with safe and high-standard electricity supply. In the coming decade, RTE plans: - 1,200 km of new underground and sub-sea DC links, along with their associated converter stations; - 600 km of existing equipment upgrades or new overhead 400 kV AC circuits substituting existing power lines. - and, at the same time, nearly 900 km of underground lines and just over 400 km of overhead 225 kV AC lines should be built. 400 projects are listed in this NDP: - 21% of the operations are on overhead lines (for 3/4 new lines or upgrade and for 1/4 dismantling of existing assets) - 27% concern new underground lines; - 52% on substation adaptations (about 20 new RTE substations and 100 new customer substations connected). Globally, nearly 80% of the network is developed underground or sub-sea. This edition of the Network Development plan is further enriched. In particular, it explains more thoroughly the link between the integration of renewable energy and the entailed development of the transmission network. It also provides a focus on smart grids. This edition relies on mid and long term scenarios describing the evolution of the

  17. WIPP: a perspective from ten years of operating success - 16189

    International Nuclear Information System (INIS)

    Gregory, Phillip C.

    2009-01-01

    The Waste Isolation Pilot Plant (WIPP), located 35 miles east of Carlsbad, New Mexico, USA is the first and, to the author's knowledge, only facility in the world for the permanent disposal of defense related transuranic (TRU) waste. Soon after plutonium was first synthesized in 1940 by a team of scientists at the University of California Berkeley Laboratory, the need to find a permanent repository for plutonium contaminated waste was recognized due to the more than 24,000 year half-life of Plutonium-239 ( 239 Pu). In 1957 the National Academy of Sciences published a report recommending deep geological burial in bedded salt as a possible solution. However, more than 50 years passed before the solution was achieved when in 1999 WIPP received the first shipment of TRU waste from Los Alamos National Laboratory. Ten years later, more than 7,600 shipments of TRU waste have been disposed of in rooms mined in an ancient salt bed more than 2,000 feet underground. This paper provides a brief history of WIPP with an overview of the technical, regulatory, and political hurdles that had to be overcome before the idea of a permanent disposal facility became reality. The paper focuses primarily on the safe, uneventful transportation program that has moved 100,000- plus containers of TRU waste from various U.S. Department of Energy (DOE) generator and/or storage sites across the Unites States to southeastern New Mexico. (author)

  18. Long-term ventilation in children: Ten years later

    Directory of Open Access Journals (Sweden)

    C. Cancelinha

    2015-01-01

    Full Text Available Introduction: Home mechanical ventilation (HMV represents a treatment option for patients with chronic respiratory failure and has changed prognosis and survival of many disorders in children. The aim of this study was to characterize a group of children on long-term mechanical ventilation (LTMV for a period longer than 10 years. Methods: A retrospective analysis was carried out including patients on LTMV for more than 10 years (LTMV-10 in a tertiary pediatric hospital. Statistical analysis: PASW Statistics 18®. Results: Thirty-one children (61% female belong to the LTMV-10 group. Median age at the beginning of ventilatory support was 3 years (birth to 13 years. Main indications for assisted ventilation were neuromuscular disease (n = 12, 39%, metabolic disease (n = 7, 23% and central hypoventilation (n = 6, 19%. Volume ventilation was used in 2 children, and positive pressure ventilation in the others, mainly bilevel positive airway pressure (n = 25, 81%. Invasive ventilation via tracheostomy was used since the beginning in four cases, and subsequently in two other children. The mean time of ventilatory support was 146 months and the maximum was 219 months. Respiratory morbidity was the most frequent cause of hospitalization and the annual rate of such episodes was 0.17 per child. Global mortality rate was 19%. Conclusions: HMV programs provide necessary and safe assistance for children with severe chronic respiratory failure. As shown in our series, it is possible to be kept on this respiratory support modality for long periods with good compliance and a small number of hospitalizations. Keywords: Long-term mechanical ventilation, Home, Chronic disease, Ten years

  19. Lateral patellar retinacular release: changes over the last ten years

    Directory of Open Access Journals (Sweden)

    Leonardo Pini Rosalem Marciano da Fonseca

    Full Text Available ABSTRACT Lateral retinacular release is a useful resource in knee surgery that can be used for disorders of the extensor mechanism. For many years, it was indiscriminately used in the treatment of the various patellofemoral joint alterations, with conflicting functional results. This study aimed to analyze the changes that have occurred in the indications and clinical effectiveness of lateral retinacular release by reviewing the relevant literature of the past ten years, comparing it to the classic literature on the subject. It was found that less extensive releases decompress the lateral patellar facet, helping with pain control, while decreasing the risks of medial subluxation. Nowadays, there is clear evidence for its indication in the lateral patellar hypercompression syndrome associated with anterior knee pain, as long as there is no related instability; furthermore, it will normally play an adjuvant role in extensor mechanism alignment surgeries for cases of recurrent patellar instability. The initial results for symptomatic patellofemoral osteoarthritis are promising when lateral release is combined with cartilage debridement; in total knee replacement, it is more commonly used for the correction of valgus deformity in order to improve the components’ congruency. Finally, distinguishing the different patellofemoral joint pathologies is seen as crucial in order to indicate this procedure. Further randomized control trials that compare surgical techniques with long-term results are still needed.

  20. Ten years of born and infeld electrodynamics investigations

    Energy Technology Data Exchange (ETDEWEB)

    Vellozo, Sergio O. [Instituto Militar de Engenharia (IME), Rio de Janeiro, RJ (Brazil); Helayel Neto, Jose Abdala [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil); Assis, Leonardo P. G. De [Stanford University (United States); Gaete, Patricio [U.S.M. (Chile)

    2013-07-01

    Full text: In this year, our group celebrates ten years of incursions in four-dimensional (3+1) Born and Infeld Electrodynamics (BIE). As is well known, BIE is a classical and nonlinear theory and it predicts a maximum finite value for the electric field, preventing the occurrence of classical singularities. It gives also finite energy for a point-like electric charge. In this period, our main effort was on BIE magnetic sector and the most significant results were: 1. the finite and well behaved magnetostatic field solution for a point-like electric charge at rest, 2. the intrinsic angular momentum (spin) as a self interaction among electric and magnetic field, 3. the cohesive resultant force, using the same natural and simple mechanism, giving stability to the electric charge. Another BIE incursion line stands for three-dimensional (2+1). We investigated the consequences of the space-time dimensionality on the existence of magnetostatic fields generated by electric charges at rest in an inertial frame, which were present in our four-dimensional version. A magnetostatic field associated with an electric charge at rest does not appear in this case. Interestingly, the addition of the topological term (Chern-Simons) to BIE yields the appearance of the magnetostatic field. Finally, we are looking for the hydrogen-like atom spectrum under the BI electrostatic potential, as well the muonic atom spectrum. (author)

  1. Goiania, ten years later. Proceedings of an international conference

    International Nuclear Information System (INIS)

    1998-12-01

    Following the radiological accident that happened in Goiania, Brazil, in late 1987, the Brazilian National Nuclear Energy Commission (CNEN) was able to turn to the international community for assistance under the terms of the 1986 IAEA sponsored Convention on Assistance in the Case of a Nuclear Accident or Radiological Emergency; this marked the first time the convention was invoked. Additionally, to prevent the loss of useful information, CNEN and the IAEA designated a panel of international experts to investigate the causes and consequences of the accident and draw up a comprehensive report, 'The Radiological Accident in Goiania', which the IAEA published in 1988. Under its nuclear safety programme, it is the IAEA's intention to follow up serious radiological accidents with review and analysis, to document the causes and circumstances and to disseminate conclusions, lessons to be learned and recommendations from which all States may benefit. A decade after the Goiania accident, the CNEN convened the international conference 'Goiania, Ten Years Later' in co-operation with the IAEA. The purpose of this conference was to share with the local population and the international community the knowledge gained during this tragic event and in the following years. The conference attracted some 400 participants from 17 countries (Argentina, Austria, Brazil, Canada, Cuba, El Salvador, Estonia, Germany, Israel, Italy, Mexico, Peru, Russian Federation, Spain, Uruguay, United States of America and Venezuela). The present IAEA proceedings contain some 50 papers selected for publication by the editorial committee of the conference

  2. The African Association for Lexicography: After Ten Years

    Directory of Open Access Journals (Sweden)

    Mariëtta Alberts

    2011-10-01

    Full Text Available

    ABSTRACT: This year it has been ten years since the establishment of AFRILEX. After an expla-nation of what led to its forming, this article gives a short overview of its composition and activi-ties.


    Keywords: AFRICAN ASSOCIATION FOR LEXICOGRAPHY (AFRILEX, AFRICAN LAN-GUAGES ASSOCIATION OF SOUTH AFRICA (ALASA, BUREAU OF THE WOORDEBOEK VAN DIE AFRIKAANSE TAAL (WAT, DICTIONARY OF SOUTH AFRICAN ENGLISH (DSAE, LINGUISTIC ASSOCIATION OF SOUTHERN AFRICA (LSSA, NATIONAL LEXICOGRAPHY UNITS (NLUs, PAN SOUTH AFRICAN LANGUAGE BOARD (PanSALB


    *****

    OPSOMMING: Die African Association for Lexicography: Ná tien jaar. Vanjaar is dit tien jaar sedert die totstandkoming van AFRILEX. Na 'n verduideliking wat tot sy stigting gelei het, gee die artikel 'n kort oorsig van sy samestelling en werksaamhede.

    Sleutelwoorde: AFRICAN ASSOCIATION FOR LEXICOGRAPHY (AFRILEX, AFRICAN LANGUAGES ASSOCIATION OF SOUTH AFRICA (ALASA, BURO VAN DIE WOORDEBOEK VAN DIE AFRIKAANSE TAAL (WAT, DICTIONARY OF SOUTH AFRICAN ENGLISH (DSAE, LINGUISTIC ASSOCIATION OF SOUTHERN AFRICA (LSSA, NASIONALE LEKSIKOGRA-FIESE EENHEDE (NLE's, PAN SUID-AFRIKAANSE TAALRAAD (PanSAT

  3. The result of ten years' study using a linac

    International Nuclear Information System (INIS)

    Torizuka, Yoshiharu

    1978-01-01

    The 300 MeV electron linear accelerator at Tohoku University has been used in various fields for the past ten years. This report reviews the major results of activities performed with this linac. For the purpose of comparison, the first part shortly reviews similar linacs and their activities in foreign countries. The second part deals with the applications to the study of nuclear structure using electron scattering. The main subjects here are transition density and giant resonance. The third application area is that of the photonuclear reactions. The studies of IAS (isobaric analogue state) in proton emission, radiation width of IAS, iso-spin effect of giant resonance, and the investigation of nuclear structures with the photoemission of π mesons are main subjects treated in this area. In the fourth part, the study of neutron scattering conducted with this linac is explained. The structural study of liquid and non-crystals, epi-thermal neutron diffraction, inelastic scattering, and the structural analysis of transient phenomena are the main subjects here. In the final part, many application studies associated with radio isotopes are shortly reviewed. It is emphasized that this linac has been very successfully used for various fields of nuclear physics. (Aoki, K.)

  4. Ten years of integrated care for the older in France

    Directory of Open Access Journals (Sweden)

    Dominique Somme

    2011-12-01

    Full Text Available Background: This paper analyzes progress made toward the integration of the French health care system for the older and chronically ill population. Policies: Over the last ten years, the French health care system has been principally influenced by two competing linkage models that failed to integrate social and health care services: local information and coordination centers, governed by the social field, and the gerontological health networks governed by the health field. In response to this fragmentation, Homes for the Integration and Autonomy for Alzheimer patients (MAIAs is currently being implemented at experimental sites in the French national Alzheimer plan, using an evidence-based model of integrated care. In addition, the state's reforms recently created regional health agencies (ARSs by merging seven strategic institutions to manage the overall delivery of care. Conclusion: The French health care system is moving from a linkage-based model to a more integrated care system. We draw some early lessons from these changes, including the importance of national leadership and governance and a change management strategy that uses both top-down and bottom-up approaches to implement these reforms.

  5. Natural gas market assessment ten years after deregulation

    International Nuclear Information System (INIS)

    1996-11-01

    Changes which have taken place in the Canadian natural gas market in the ten years since the gas market was de-regulated, were reviewed. A 1985 agreement created conditions for a competitive natural gas market. However, the National Energy Board ensured that the pipeline transmission sector of the gas industry would continue to be regulated because of its natural monopoly characteristics. Open non-discriminatory access was to be provided to all shippers on inter-provincial gas pipelines. One objective of this report was to provide the Board with the means of assuring itself that the market was operating in such a way that Canadian requirements for natural gas were being met at fair market prices. The report also provided a review of the major changes in the gas producing and transmission sector, and reviewed developments in gas markets and sales practices. The overall assessment was that the natural gas industry was efficient and responsive to the demands of the marketplace. 5 tabs., 30 figs

  6. Holistic System of Care: a ten-year perspective.

    Science.gov (United States)

    Nebelkopf, Ethan; Wright, Serena

    2011-01-01

    The Holistic System of Care for Native Americans in an Urban Environment is a community-focused intervention that provides behavioral health care, promotes health, and prevents disease. This approach is based on a community strategic planning process that honored Native American culture and relationships. Substance abuse, mental illness, homelessness, poverty, crime, physical illness, and violence are symptoms of historical trauma, family dysfunction, and spiritual imbalance. The holistic model links treatment, prevention, and recovery. The link between prevention and treatment is early intervention. Peer support is the link between treatment and recovery. Recovering individuals serve as role models linking recovery to prevention. Culture and spirituality build a strong and resilient foundation for recovery. This article documents the effectiveness of the holistic model over a ten-year period that it has been implemented at the Family & Child Guidance Clinic of the Native American Health Center in the San Francisco Bay Area. The holistic model has produced statistically significant reductions in substance abuse among adult Native American women, men, reentry, and homeless populations; reductions in substance abuse among Native American adolescents; reductions in HIV/AIDS high-risk behavior among Native American men, women, and adolescents; and decreases in acting out behavior among Native American severely emotionally disturbed children.

  7. [Ten years after the latest revision International Anatomical Terminology].

    Science.gov (United States)

    Kachlík, D; Bozdechová, I; Cech, P; Musil, V; Báca, V

    2008-01-01

    Ten years ago, the latest revision of the Latin anatomical nomenclature was approved and published as Terminologia Anatomica (International Anatomical Terminology), and is acknowledged by the organization uniting national anatomical societies--International Federation of Associations of Anatomists. The authors concentrate on new terms included in the nomenclature and on the linguistic changes of terminology. The most frequent errors done by medical specialists in the usage of the Latin anatomical terminology are emphasized and the situation of eponyms in contemporary anatomy is discussed in detail as well. The last version of the nomenclature makes its way very slowly in the professional community and it is necessary to refer to positive changes and advantages it has brought. The usage of this Latin anatomical nomenclature version is suggested by the International Federation to follow in theoretical and clinical fields of medicine. The authors of the article strongly recommend using the recent revision of the Latin anatomical nomenclature both in the oral and written forms, when educating and publishing.

  8. [After ten years of AIDS, a vision emanating from feminism].

    Science.gov (United States)

    Liguori, A L

    1991-01-01

    AIDS and the economic crisis in Mexico are threatening the epidemiologic transition in which infectious diseases ceased to be the only major cause of death and chronic degenerative diseases began to account for a growing proportion of deaths. Many factors combined to produce the sexual, gay, and women's liberation movements beginning in the 1970s. At the beginning of the feminist movement, women proposed different kinds of interpersonal relations both between women and with men. Women together realized their rights to control their own bodies, to sexual enjoyment, to abortion, and to free themselves of feelings of shame and guilt. The weight of moral pressures was lessened and the personal desires of the woman assumed a greater role in selection of sexual partners. Conservative forces grew stronger in the 1980s, and the proliferation of sexually transmitted diseases began to imperil the sexual revolution. But these setbacks were minor compared to AIDS. Now, 10 years after its appearance, it is clear that AIDS is not limited to homosexual men. The number of cases in Mexico increased from none 10 years ago to some 10,000 estimated cases reported and unreported today. 1/6 of the cases are in women. Many women and heterosexuals felt immune from AIDS in the beginning, and some still do, but many more have become aware of the danger. Women now fear contracting AIDS, but they also fear confronting their partners to suggest that they use condoms. Denial may play a role, but deeply rooted cultural factors that women may recognize but fee powerless to change may also be at play. Many women over 30 have difficulty taking the initiative in sexual matters. They are embarrassed to buy condoms and even more embarrassed to propose their use. They imagine that men will consider them "loose" if they carry condoms. Mexican women are poorly prepared to tell their men explicitly what they want sexually, and Mexican men are also poorly equipped to ask what women want, accustomed as they

  9. Sclerotherapy of Plummer's disease - A critical ten year review

    International Nuclear Information System (INIS)

    Sandrock, D.; Humplik, B.I.; Munz, D.L.

    2002-01-01

    Aim: Since ten years sclerotherapy with ethanol is proposed for the treatment of Plummer's disease (unifocal autonomy). Hence, it was the aim of this study to evaluate critically all the sclerotherapies performed in our institution. Special attention should be given to the long-term results. Material and Methods: In the study enrolled were 47 consecutive patients with Plummer's disease, who were referred to sclerotherapy with ethanol since 1991 (10 men, 37 women, aged 24-79 years). The diagnosis of unifocal autonomy was proven in all patients by scintigraphy under TSH-suppressed conditions. 31 patients had latent, 16 manifest hyperthyroidism, 12 of these under antithyroid medication. All patients received ultrasound guided infiltrations of 0.5-2 ml 96 % ethanol into the autonomy. The procedure was repeated at intervals (individually between 1 week and 3 months) until there was A) sufficient success, B) partial success or C) the patient refused further infiltrations. Results: Overall, 407 infiltrations were performed. The number of infiltrations per patient reached from 1 to 63 (mean 7). The side effects included 2 cases of a (transient) paresis of the recurrent nerve and pain/discomfort in 32 %. The therapy was finished successfully (group A; normal TSH, normalisation of the scintigraphic pattern) in 17 patients, partially successfully (group B; change from manifest to latent hyperthyroidism and/or TSH > 0.1 mU/l, scintigram not completely normalized) in 12 patients, and without success (group C) in 16 patients - 2 changed to surgery, 4 to radioiodine therapy, 3 continued antithyroid medication and 4 refused therapy without further comments. Excluding 2 patients from group B (with 35 and 61 infiltrations, respectively) there was no significant difference between A, B, and C in the parameters uptake under suppression, volume of the autonomy, laboratory values, number of infiltrations, age or sex. Conclusion: The sclerotherapy with ethanol, consequently performed, is

  10. The experience of ABACC after ten years applying safeguards

    International Nuclear Information System (INIS)

    Feu Alvim, Carlos A.; Palacios, Elias; Esteves dos Santos, Jose M.; Oliveira, Antonio

    2001-01-01

    Full text: During the second half of this century, Argentina and Brazil shared a common ambition: to gain knowledge on and develop the technology required for attaining a full command of the nuclear fuel cycle. Until mid-1990's, neither of these countries had fully adhered to the Tlatelolco Treaty, nor had they signed the Non-Proliferation Treaty (NPT), as a way to protect themselves towards the development of such technology. The discriminatory nature of the NPT was the argument used to resist the international pressure for its signature. On the other hand, the text of the Tlatelolco Treaty involved special inspections to non-declared facilities that meant a threat of industrial espionage which Argentina and Brazil wanted to avoid. This position -maintained for almost two decades - led the international community to view these countries as competing for nuclear supremacy. As of 1985, both Argentina and Brazil, by means of joint declarations, expressed their decision to provide transparency to their nuclear programs. Consequently, they undertook several commitments concerning the exclusively peaceful purposes in their use of nuclear energy and in their respective nuclear programs. This process of joint declarations led to the signature of a Bilateral Agreement for the Exclusively Peaceful Uses of Nuclear Energy in July 1991. Through this agreement, they formally established their Common System of Accounting and Control of Nuclear Materials (SCCC) and created the Brazilian-Argentine Agency for Accounting and Control of Nuclear Materials (ABACC) in order to implement the established verification system. Also at that time, the decision was made to start negotiations with the International Atomic Energy Agency (IAEA) towards a joint agreement on safeguards based on the SCCC. In March 1994, the Quadripartite Agreement between Argentina, Brazil, the ABACC and the IAEA entered into force. The experience in the application of SCCC during its first ten years and the

  11. Pierre Bourdieu, dez anos depois Pierre Bourdieu, ten years after

    Directory of Open Access Journals (Sweden)

    Cristina Carta Cardoso de Medeiros

    2013-03-01

    Full Text Available O presente texto procura discutir o legado deixado pelo sociólogo francês Pierre Bourdieu. Dez anos após sua morte, tem-se discutido, em nível internacional, a relevância deste autor, um dos mais influentes e citados teóricos do mundo. Para a identificação desta influência no Brasil, mais especificamente no campo educacional brasileiro, pesquisou-se nas teses e dissertações encontradas no banco de dados da CAPES, que referenciavam Bourdieu, de que forma estaria se dando a apropriação de seu quadro teórico de análise para construção de conhecimento no referido campo. Concluiu-se que o número de produções defendidas nos Programas de Pós-Graduação em Educação no Brasil, de 1965 a 2010, cresce de forma exponencial, demonstrando o quão profícua a utilização da teoria sociológica de Bourdieu tem se mostrado para explicar a realidade da Educação no Brasil na contemporaneidade. Encerra-se o artigo com uma reflexão sobre a consideração do status de Bourdieu como um clássico da Sociologia que, paradoxalmente, se mostra mais atual e vivo do que qualquer outro autor quando se trata de aplicar seu princípio maior, a saber, analisar o mundo social e suas lógicas, desvelando as formas de dominação e as misérias sociais.This paper's intent is to discuss the legacy left by the French sociologist Pierre Bourdieu. Ten years after his death, it has been discussed at an international level the relevance of this author, one of the most cited and influential theorists in the world. To identify such influence in Brazil, more specifically in the Brazilian educational field, we investigated theses and dissertations found in CAPES database, which referenced Bourdieu, to identify how those works use his theoretical framework of analysis for construction of knowledge in that field. It was concluded that the number of productions held in post-graduate programs in education in Brazil, from 1965 to 2010, grows exponentially

  12. Inspection of Chooz power plant after ten years operation

    International Nuclear Information System (INIS)

    Saglio, Robert.

    1978-01-01

    This report is intended to discuss the results from the complete technical audit of the vessel effected in 1976 at the Ardennes reactor (CNA 305 MWe). This audit had a special character as far as this power plant has never been inspected before: the start-up had taken place in 1967 and was then prior to the development of French regulations (and even to the first version of the ASME code, Section XI). In that time, no inspection was expected; it has yet been possible to have a complete audit in ten days. The automatic start-up of focused ultrasonic testing so appeared to have reached the required reliability and a good sensitivity [fr

  13. A ten-year histopathological study of generalised lymphadenopathy ...

    African Journals Online (AJOL)

    This study was undertaken to study the histopathology of generalised lymphadenopathy in India, as well as the demographics of the study population. Method: This study was conducted for a period of 10 years (August 1997-July 2007), of which eight years were retrospective, from August 1997-July 2005, and two years ...

  14. Ten-year Clinical Performance of Posterior Resin Composite Restorations.

    Science.gov (United States)

    Krämer, Norbert; Reinelt, Christian; Frankenberger, Roland

    2015-08-01

    To investigate the clinical behavior of two different resin-based restorative systems in Class II cavities in a controlled prospective split-mouth study over 10 years. Thirty patients received 68 resin composite restorations (Solobond M + Grandio: n = 36; Syntac + Tetric Ceram: n = 32) by one dentist in a private practice. 35% of cavities revealed no enamel at the bottom of the proximal box, 48% of cavities provided Grandio restoration suffered marginal fracture with exposed dentin and one Tetric Ceram restoration failed due to cusp fracture. After 10 years, Grandio showed higher surface roughness (p = 0.03) and less color match (p = 0.024; Mann-Whitney U-test). Molar restorations performed worse than premolar fillings regarding marginal integrity (4 and 10 years), filling integrity (4, 8, and 10 years), and tooth integrity (4, 8, and 10 years). The main reasons for degradation of resin composites were chipping and cracks in molar restorations after 8 years. Beyond the 4-year recall, marginal staining increased (43% bravo for stained margins at four years, 52% at 8 years, and 71% at 10 years). Tooth integrity deteriorated significantly due to more enamel cracks and chipping over time (9% at baseline and 89% after 10 years (p<0.05). Direct resin composite restorations performed satisfactorily over 10 years of clinical service.

  15. Ten-year retrospective: OPEC and the world oil market

    Energy Technology Data Exchange (ETDEWEB)

    Gately, D.

    1984-09-01

    This paper reviews the main events in the world oil market since 1973 and some major explanations as to what happened and why (Section I). Then there is a discussion of some projections for the next two decades and of some implications of various theories about OPEC's decisionmaking process (Section II). Section III summarizes what we have learned about modeling OPEC and the world oil market. This includes: the dominant theoretical approach based on the wealth-maximization model of Harold Hotelling (1931); the simulation approach most common in the applied literature, which envisages target-capacity-utilization pricing by OPEC; and the difficult problem of modeling price behavior during disruptions. Finally, Section IV discusses some important unresolved issues, both theoretical and empirical. A variety of contributions to the literature are considered, but the discussion pays special attention to two important recent works. One is the book OPEC Behavior and World Oil Prices (1982) (EAPA 9:3899) edited by James Griffin and David Teece, an important collection of papers on OPEC and world oil, prepared for a 1981 conference at the University of Houston. The other is the 1980 to 1981 world oil study by the Energy Modeling Forum of Stanford Univesity, which involved ten prominent models of the world oil market. 31 references.

  16. Effects of ten years treated wastewater drip irrigation on soil ...

    African Journals Online (AJOL)

    SWEET

    soil contamination and the cumulative impact of wastewater, we compared two plots, all under orange- grove that had been drip irrigated for 10 years. .... evaluated human risk of the organic contaminants in reclaimed wastewater used for ... of our study was to evaluate the effects of treated waste- water irrigation, of 10 years' ...

  17. The future of the Dutch public library: ten years on

    NARCIS (Netherlands)

    Frank Huysmans; Carlien Hillebrink

    2008-01-01

    The public library is the biggest cultural institution in the Netherlands, with around 4 million members and 130 million items lent each year. Inspite of this, the library is under pressure: membership numbers and borrowings have been declining steadily for several years. In the last six

  18. Ten-year survival of patients with oesophageal squamous cell ...

    African Journals Online (AJOL)

    Objectives. The standard predictive factors of actuarial survival such as T and N stage become less important as patients live for more than 10 years after treatment of cancer. Reports of actual 10-year survivors of oesophageal squamous cell carcinoma (SCC) are rare, and demographic and clinicopathological factors ...

  19. Odontogenic Mixoma in a Ten-Year-Old Patient.

    Science.gov (United States)

    Triana, Ennya Lieseth Leonel; Melo-Uribe, Mario; Castro-Núñez, Jaime

    2016-10-01

    Odontogenic myxomas are benign, rarely seen intraosseous tumors arising from the embryonic connective tissue associated to tooth formation. The authors present the case of a 10-year-old patient affected by this entity.

  20. Prevalence of loneliness over ten years among the oldest old.

    Science.gov (United States)

    Nyqvist, Fredrica; Cattan, Mima; Conradsson, Mia; Näsman, Marina; Gustafsson, Yngve

    2017-06-01

    This study examined the prevalence of loneliness among the oldest old within a 10-year period and studied the influence of various sociodemographic, social and health characteristics on loneliness. The study used population-based data from the Umeå85+/GErontological Regional DAtabase-study (GERDA) for the years 2000-2002, 2005-2007 and 2010-2012 including 85-year-old, 90-year-old and ⩾95-year-old participants. A final sample of 304 participants in 2000-2002, 329 participants in 2005-2007 and 401 participants in 2010-2012 was included in the analyses. Although the level of loneliness was already high in 2000-2002 (49.3% reported frequent loneliness), the results showed limited changes in loneliness during the 10-year study period. Loneliness was closely related to living alone, depressive symptoms and living in institutional settings. Although societal changes such as solitary living and growing urbanization suggest a changing trend in loneliness, we found that the prevalence of loneliness was relatively stable in this study. Nevertheless, loneliness is common among the oldest old and a focus on social issues related to living arrangements and on depressive symptoms is important in understanding loneliness.

  1. Ten year neurocognitive trajectories in first-episode psychosis

    DEFF Research Database (Denmark)

    Barder, Helene E; Sundet, Kjetil; Rund, Bjørn R

    2013-01-01

    Objective: Neurocognitive impairment is commonly reported at onset of psychotic disorders. However, the long-term neurocognitive course remains largely uninvestigated in first episode psychosis (FEP) and the relationship to clinically significant subgroups even more so. We report 10 year longitud......Objective: Neurocognitive impairment is commonly reported at onset of psychotic disorders. However, the long-term neurocognitive course remains largely uninvestigated in first episode psychosis (FEP) and the relationship to clinically significant subgroups even more so. We report 10 year...... longitudinal neurocognitive development in a sample of FEP patients, and explore whether the trajectories of cognitive course are related to presence of relapse to psychosis, especially within the first year, with a focus on the course of verbal memory. Method: Forty-three FEP subjects (51% male, 28 ± 9 years...... of illness. We conclude that worsening of specific parts of cognitive function may be expected for patients with on-going psychosis, but that the majority of patients do not show significant change in cognitive performance during the first 10 years after being diagnosed....

  2. Naive (commonsense) geography and geobrowser usability after ten years of Google Earth

    Science.gov (United States)

    Hamerlinck, J. D.

    2016-04-01

    In 1995, the concept of ‘naive geography’ was formally introduced as an area of cognitive geographic information science representing ‘the body of knowledge that people have about the surrounding geographic world’ and reflecting ‘the way people think and reason about geographic space and time, both consciously and subconsciously’. The need to incorporate such commonsense knowledge and reasoning into design of geospatial technologies was identified but faced challenges in formalizing these relationships and processes in software implementation. Ten years later, the Google Earth geobrowser was released, marking the beginning of a new era of open access to, and application of, geographic data and information in society. Fast-forward to today, and the opportunity presents itself to take stock of twenty years of naive geography and a decade of the ubiquitous virtual globe. This paper introduces an ongoing research effort to explore the integration of naive (or commonsense) geography concepts in the Google Earth geobrowser virtual globe and their possible impact on Google Earth's usability, utility, and usefulness. A multi-phase methodology is described, combining usability reviews and usability testing with use-case scenarios involving the U.S.-Canadian Yellowstone to Yukon Initiative. Initial progress on a usability review combining cognitive walkthroughs and heuristics evaluation is presented.

  3. Ten years to VISION 2020: how are we doing?

    Directory of Open Access Journals (Sweden)

    Peter Ackland

    2010-12-01

    Full Text Available We have just passed the halfway mark for the VISION 2020 global initiative, which was launched in 1999 with the goal to eliminate avoidable blindness by the year 2020. This is a good time to take stock of what we have achieved and what still needs to be done.

  4. Chandra: Ten Years of Amazing Science with a Great Observatory

    Science.gov (United States)

    Weisskopf, Martin C.

    2009-01-01

    We review briefly review the history of the development of the Chandra X-Ray Observatory, highlighting certain details that many attendees of this Conference might not be aware of. We then present a selection of scientific highlights of the first 10 years of this remarkable and unique mission.

  5. Epidemiological analysis of tuberculosis in Ethiopia: A ten-year ...

    African Journals Online (AJOL)

    The data on the indicators have undergone five stages of analysis: Aggregation, computation, summarization, graphics and model fitting. The incidence rate of tuberculosis is increasing in Ethiopia at a rate of 5 new TB cases per 100,000 population per year. Urban agro-ecological zones have been more affected by the ...

  6. NHS litigation in bariatric surgery over a ten year period.

    Science.gov (United States)

    Ratnasingham, Kumaran; Knight, James; Liu, Mamie; Karatsai, Eleni; Humadi, Samer; Irukulla, Shashi

    2017-04-01

    Negligence claims in the UK NHS has increased over the last 30 years. The aim of this present study was determine the number of claims and the cost of litigation in Bariatric Surgery and compare it to similar other specialties. Data was received from NHS Litigation Authority (NHSLA) in response to Freedom of Information data request. There was a total of 7 claims, of which 4 were successful. The total pay out sum was £210,000 in 10 years. This is a very low amount compared to other surgical specialties. This low level of litigation probably indicates that the current bariatric surgical services in the NHS are delivering safe care with good patient satisfaction. This needs to be carefully considered prior to changing the payment tariffs for bariatric surgery. Copyright © 2017 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.

  7. 1959 - 1969 Ten years in the life of a machine

    CERN Multimedia

    1969-01-01

    Operation and development of the PS have brought a dramatic improvement in its capabilities. This article describes the years of getting to know the machine and of developing its potential, picking out some major landmarks on the way. The article was put together with the help of P.H. Standley (PS Division Head), C.S. Taylor (Linac), G. Plass, W. Richter (Mam Ring), M. Georgijevic (Power Supply), J.H.B. Madsen (Operation), and G.L. Munday (Experimental Areas).

  8. Overweight and lifestyle in ten-year old children

    OpenAIRE

    Garmy, Pernilla; Sivberg, Bengt

    2007-01-01

    Overweight in childhood and adolescence is a major public health problem due to its medical and psychosocial consequences. The aim of this study was to investigate overweight and life style factors in children aged 10. The sample consisted of 138 children 10 years of age from three public primary schools in southern Sweden from whom data on height, weight, Body Mass Index (BMI) and life style were obtained during 2003–2004. Differences in life style factors between the overweight and the non-...

  9. Ten years of descending necrotizing mediastinitis: management of 23 cases.

    Science.gov (United States)

    Roccia, Fabio; Pecorari, Gian Carlo; Oliaro, Alberto; Passet, Ettore; Rossi, Paolo; Nadalin, Juri; Garzino-Demo, Paolo; Berrone, Sid

    2007-09-01

    Through a 10-year retrospective study, we report our experience in the management of descending necrotizing mediastinitis (DNM), a rare and often lethal complication of odontogenic and oropharyngeal infections. We reassessed 23 patients between the ages of 16 and 69 years (mean, 49 years) seen between 1996 and 2005, with DNM secondary to odontogenic abscess or phlegmon in 9 cases or secondary to peritonsillar abscess in 14 cases. In this study, 48% of the patients had immune system disorders, mainly diabetes mellitus (6 patients). The diagnosis of DNM was confirmed by cervicothoracic computed tomography. Eight patients underwent a bilateral collar cervicotomy, and 15 underwent a combined cervicothoracic approach. Five, 2, 1, and 1 patients underwent surgery 2, 3, 4, and 5 times, respectively. Seven patients died as a result of septic shock and multiorgan failure, for a mortality rate of 30.4%. Four of those who died had a compromised immune system. The relatively high mortality rate seen in this study shows that, in addition to early diagnosis and aggressive treatment, it is important to give greater attention to and be more medically and surgically aggressive in the management of patients whose immune system is compromised in any way.

  10. Ten Years Back, Five Years Forward: The Data Seal of Approval

    OpenAIRE

    Ingrid Dillo; Lisa de Leeuw

    2015-01-01

    If we want to share data, the long-term storage of those data in a trustworthy digital archive is an essential condition. Trust is the basis of storing and sharing data. That trust must be present in the various stakeholders involved. Certification of digital archives can make an important contribution to the confidence of these stakeholders in the digital archives.Ten years ago DANS was assigned the task of developing a Seal of Approval for digital data to ensure that archived data can still...

  11. [Ten years of destructive eyeball surgery in Lomé].

    Science.gov (United States)

    Vonor, K; Amedome, K M; Dzidzinyo, K; Ayena, K D; Santos, M K A; Maneh, N; Tete, Y; Balo, K P

    2015-01-01

    Destructive surgery of the eyeball comprises radical procedures - evisceration, enucleation, and exenteration - with various indications. The purpose of this study was to determine the features of these procedures in Lomé. We conducted a retrospective study reviewing records for all patients undergoing these procedures in 3 ophthalmic centers in Lomé in the decade from 2002 through 2011. Of 6240 eye operations, 76 involved one of these three procedures, for a frequency of 1.2%. Patients' mean age was 40.1 ± 26.9 years (range: 1 day to 91 years). The sex ratio (of men to women) was 1.2. The principal indications were staphyloma (38%), ocular and orbital tumors (30%), and phthisis bulbi (24%). Retinoblastoma was the leading type of ocular/orbital tumor (52%). Local anesthesia was performed in 64% of cases, and general anesthesia in 36%. Evisceration was practiced in 67% of cases, enucleation in 24%, and exenteration in 9%. An ocular prosthesis was placed in 46%. Staphyloma was the leading indication for destructive surgery. Given the damage of this type of procedure, primary prevention is important, including early and adequate management of ocular conditions.

  12. Adoption research, practice, and societal trends: Ten years of progress.

    Science.gov (United States)

    Wiley, Mary O'Leary

    2017-12-01

    Adoption involves the legal transfer of parental rights and responsibilities from a child's birth parents to adults who will raise the child (Reitz & Watson, 1992). Research related to adoption has expanded over the past 10 years and has incorporated more focus on implications for practice and public policy. This expansion has reflected increased awareness of the lived experience of adopted individuals, in addition to that of adoptive families and birth or first parents and families, collectively known as the adoption kinship network (Grotevant & McRoy, 1998). Trends discussed included research and social trends or movements (2007-2017) since the publication of the final article in a series of articles in the psychological literature related to adoption in The Counseling Psychologist (Baden & Wiley, 2007; Lee, 2003; O'Brien & Zamostny, 2003; Wiley & Baden, 2005; Zamostny, O'Brien, Baden, & Wiley, 2003; Zamostny, Wiley, O'Brien, Lee, & Baden, 2003). This article summarizes the social trends and research related to adoption over the last 10 years, including longitudinal and meta-analytic studies, increased research and conceptualization of ethnic and racial identity development, research on microaggressions, and research on diverse adoptive families, including those with gay and lesbian parents. Social trends included increased knowledge related to Internet accessibility, genetic information, continued focus on openness, and viewing adoption through a more critical lens. Implications are discussed for the development of programs that enhance competence of mental health professionals and adoption professionals in adoption-competent practice. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  13. Ten-year publication trends in dermatology in mainland China.

    Science.gov (United States)

    Xin, Shujun; Mauro, Jacqueline A; Mauro, Theodora M; Elias, Peter M; Man, Mao-Qiang

    2014-10-01

    China has been experiencing huge changes in all aspects, including dermatologic research, since its reform in 1978. However, it is not known how the economic and intellectual development has influenced the publication trends in the field of dermatology, which could mirror the scientific development in other medical disciplines. In the present study, we analyzed publication trends from dermatology departments in mainland China from 2002 to 2011. All publication data were obtained from www.pubmed.com. Only papers published from dermatology departments in mainland China were used for analysis. The number of publications increased 10-fold over this 10-year period. A total of 1231 articles were published in English in 251 journals between 2002 and 2011. A total of 129 journals published only one paper from dermatology departments in mainland China. Over 60% of articles were original research, and 21.7% were case reports. Among these 251 journals, foremost was the Journal of Clinical Experimental Dermatology, which published 5.9% of all papers from mainland China; 2.7% of papers were published in the Journal of Investigative Dermatology. The number of publications positively correlated with the changes in gross domestic product per capita during the study period. These results suggest that the number of publications in the dermatology field has increased markedly in mainland China over the last 10 years. This dramatic increase in publications could be attributed, at least partially, to the significant improvement in economic conditions in mainland China. © 2013 The International Society of Dermatology.

  14. Otological Findings Ten Years after Myringotomy with Tympanostomy Tube Insertion

    Directory of Open Access Journals (Sweden)

    Ali Goljanian Tabrizi

    2011-01-01

    Full Text Available Introduction: To study the long-term complications of tympanostomy tube insertion in young children 10 years after surgery.   Materials and Methods: In September 2011, the medical records of all patients who had undergone myringotomy with tympanostomy tube insertion between February 2000 and March 2001 at the two general hospitals of Isfahan University of Medical Sciences were studied. Of the 98 patients who fulfilled the inclusion criteria, 82 patients agreed to participate and were enrolled in the study. The complications of the operation were evaluated in these patients.   Results: Of the 164 ears that were operated on, myringosclerosis was found in 17.1%, atrophy of the tympanic membrane in 1.2%, permanent perforation of the tympanic membrane in 0.6% and tympanic membrane atelectasis in 0.6%. None of the patients developed cholesteatoma as a complication of tympanostomy tube insertion.   Conclusion:  Considering the low risk of serious complications after 10 years, tympanostomy tube insertion is a safe and effective treatment option in the treatment of otitis media with effusion.

  15. Ten Years of Landscape Genomics: Challenges and Opportunities

    Directory of Open Access Journals (Sweden)

    Yong Li

    2017-12-01

    Full Text Available Landscape genomics is a relatively new discipline that aims to reveal the relationship between adaptive genetic imprints in genomes and environmental heterogeneity among natural populations. Although the interest in landscape genomics has increased since this term was coined, studies on this topic remain scarce. Landscape genomics has become a powerful method to scan and determine the genes responsible for the complex adaptive evolution of species at population (mostly and individual (more rarely level. This review outlines the sampling strategies, molecular marker types and research categories in 37 articles published during the first 10 years of this field (i.e., 2007–2016. We also address major challenges and future directions for landscape genomics. This review aims to promote interest in conducting additional studies in landscape genomics.

  16. First ten years of hinode solar on-orbit observatory

    CERN Document Server

    Imada, Shinsuke; Kubo, Masahito

    2018-01-01

    This book provides the latest scientific understanding of the Sun, sharing insights gleaned from the international solar physics project Hinode. The authors (who are the main project contributors) review, from the various viewpoints, the discoveries and advances made by the on-orbit operations of the Hinode spacecraft in its first decade. Further, they present a wealth of scientifically important photographs and data from Hinode. Launched in September 2006, Hinode is the third Japanese solar observatory on orbit, and employs three highly advanced telescopes jointly developed and operated with international partners. The book describes the background of these research topics, how the Hinode telescopes have tackled various challenges, and the scientific achievements and impacts in the first 10 years. Furthermore, it explores future perspective of researches in Japan. The book will benefit undergraduate students interested in recent advance in the solar research, as well as graduate students and researchers work...

  17. First ten years of Hinode solar on-orbit observatory

    CERN Document Server

    Imada, Shinsuke; Kubo, Masahito

    2018-01-01

    This book provides the latest scientific understanding of the Sun, sharing insights gleaned from the international solar physics project Hinode. The authors (who are the main project contributors) review, from the various viewpoints, the discoveries and advances made by the on-orbit operations of the Hinode spacecraft in its first decade. Further, they present a wealth of scientifically important photographs and data from Hinode. Launched in September 2006, Hinode is the third Japanese solar observatory on orbit, and employs three highly advanced telescopes jointly developed and operated with international partners. The book describes the background of these research topics, how the Hinode telescopes have tackled various challenges, and the scientific achievements and impacts in the first 10 years. Furthermore, it explores future perspective of researches in Japan. The book will benefit undergraduate students interested in recent advance in the solar research, as well as graduate students and researchers work...

  18. Purpose in life predicts allostatic load ten years later.

    Science.gov (United States)

    Zilioli, Samuele; Slatcher, Richard B; Ong, Anthony D; Gruenewald, Tara L

    2015-11-01

    Living a purposeful life is associated with better mental and physical health, including longevity. Accumulating evidence shows that these associations might be explained by the association between life purpose and regulation of physiological systems involved in the stress response. The aim of this study was to investigate the prospective associations between life purpose and allostatic load over a 10-year period. Analyses were conducted using data from the Midlife in the United States (MIDUS) survey. Assessment of life purpose, psychological covariates and demographics were obtained at baseline, while biomarkers of allostatic load were assessed at the 10-year follow-up. We found that greater life purpose predicted lower levels of allostatic load at follow-up, even when controlling for other aspects of psychological well-being potentially associated with allostatic load. Further, life purpose was also a strong predictor of individual differences in self-health locus of control-i.e., beliefs about how much influence individuals can exert on their own health-which, in turn, partially mediated the association between purpose and allostatic load. Although life purpose was also negatively linked to other-health locus of control-i.e., the extent to which individuals believe their health is controlled by others/chance-this association did not mediate the impact of life purpose on allostatic load. The current study provides the first empirical evidence for the long-term physiological correlates of life purpose and supports the hypothesis that self-health locus of control acts as one proximal psychological mechanism through which life purpose may be linked to positive biological outcomes. Copyright © 2015. Published by Elsevier Inc.

  19. Stakeholder perceptions of a school food policy ten years on.

    Science.gov (United States)

    Pettigrew, Simone; Talati, Zenobia; Sauzier, Megan; Ferguson, Amanda

    2018-01-24

    To assess (i) the extent to which stakeholders have accepted and implemented a Healthy Food and Drink Policy for schools a decade after its introduction and (ii) any resulting implications for canteen profitability. Online survey distributed via electronic newsletter to school principals. Western Australian public schools. Principals, teachers, canteen managers, and parents and citizens committee presidents (n 307). Large majorities of respondents reported that the policy has made the foods and drinks provided in schools healthier (85 %) and that the policy constitutes a good opportunity to teach children about healthy eating (90 %). Only small proportions of respondents felt it had been difficult to implement the policy in their schools (13 %) or that the policy fails to accommodate parents' rights to choose the foods consumed by their children (16 %). Most of the policy outcomes assessed in both the initial post-implementation evaluation (2008) and the 10-year follow-up evaluation (2016) demonstrated significant improvement over time. The study results indicate that comprehensive school food policies can favourably influence the foods and drinks provided on school premises and can be highly acceptable to key stakeholders, without adversely affecting profitability. The results are encouraging for policy makers in other jurisdictions considering the implementation of similar policies.

  20. Temperament and character in eating disorders: ten years of studies.

    Science.gov (United States)

    Fassino, S; Amianto, F; Gramaglia, C; Facchini, F; Abbate Daga, G

    2004-06-01

    In recent years a number of studies of personality have been performed in subjects with Eating Disorders (EDs) to investigate the clinical differences between controls and ED patients and among EDs subtypes, and its role in the development and course of symptoms. The Tridimensional Personality Questionnaire (TPQ) and the Temperament and Character Inventory (TCI) have been widely used at this purpose, allowing the description of specific temperament and character profiles for EDs. High Harm Avoidance (HA) and low Self-Directedness (SD) are shared by all EDs. Slight differences on some facets have been found among ED subgroups. Nevertheless, HA is influenced by mood and both high HA and low SD are personality traits shared by many mental disorders, whose specificity is rather low. Restrictor anorectics are characterized by high Persistence (P) and a relatively higher SD, and bulimics by higher Novelty Seeking (NS) and the lowest SD, while binge/purging and purging anorectics share some traits with anorexia and some with bulimia. Though current data justify the discrimination among anorexia subtypes, they are not in contrast with the thesis of a continuum in ED personality traits. Since some personality traits display a prognostic value with regard to therapy and clinical outcome, further studies are needed on treatments and prognostic factors in EDs. Moreover, studies attempting to define the neurobiological and genetic correlates of temperament should be supported by clinical pharmacological trials.

  1. Stevens Johnson syndrome in Pakistan: a ten-year survey.

    Science.gov (United States)

    Ahmed, Y I; Azeem, S; Khan, O; Majid, T H; Ahmed, D; Amin, A; Mahmood, A; Hameed, K

    2004-06-01

    A pre-tested questionnaire-based, retrospective study to highlight the causative factors, mode of presentation, complications and outcome of patients with Stevens Johnson syndrome. Aga Khan University Hospital over a 10 year period. All case records with a diagnosis of Steven Johnson Syndrome in the period 1990 to 2000 were retrospectively reviewed. Data was retrieved on a comprehensive questionnaire. The demographic variatbles and drugs taken within the previous 21 days were noted. Date analysis was done by Epi-Info Version 6.0. Of the 101 studied patient files, the most common offender was found to be the Penicillins as a group and Sulfadoxine-Pyrimethamine (Fansidar) when considering all drugs individually. Most common complications included electrolyte disturbances (13.9%) and congestive heart failure (6.9%). Mortality rate was high at 10.1%. SJS was found to be a rare condition but having a mortality rate of 10.1%. As it can be induced by a large number of drugs, caution should be practiced while prescribing.

  2. Clinicopathological features of liver tumours: a ten-year study

    International Nuclear Information System (INIS)

    Zahir, S.T.; Aalipour, E.

    2015-01-01

    Various diseases affect the liver, among them, malignant and benign tumours with hepatic nodules are the most important. We aimed to evaluate the clinicopathological findings related to hepatic tumours and nodules. Methods: This retrospective study was carried out during November 2014 to August 2015 by reviewing the hospital medical records of 164 registered patients with liver biopsies referred to Shahid Sadoughi educational General Hospital, Yazd, Iran, between 2004 and 2014. The samples were selected through the census method. Age, gender, clinical symptoms, initial clinical diagnosis, pathology reports and ultrasound results were considered as variables. Data were analysed by using SPSS-17. Results: There were 87 (53%) men and 77 (47%) women. The mean ages of presentation for malignant and benign tumours were 57.9 ±17.2 and 44.9±19.4 years, respectively. Seventy benign tumours and 147 malignant tumours were recorded. The most frequent chief complaint was abdominal pain (54.9%) in both malignant (56.50%) and benign tumours (41.20%). Hepatocellular carcinoma (HCC) and hemangioma were the most prevalent malignant and benign hepatic tumours, respectively. In our study, correlation between pathology reports and primary diagnoses was 40.9%, and a significant relationship was found between sonography and pathological findings (p=0.038). Conclusions: We found that only when primary clinical diagnosis and sonography were in favour of malignancy, they were correlated with pathology results. Clinicopathological assessments can help physicians in their diagnosis in order to facilitate the management of hepatic tumours. (author)

  3. Head and neck lymphomas - a retrospective ten-year observation.

    Science.gov (United States)

    Niemiec, Marcelina; Stryjewska-Makuch, Grażyna; Janik, Małgorzata; Kolebacz, Bogdan; Lisowska, Grażyna; Ścierski, Wojciech

    2017-01-01

    Lymphomas are a heterogeneous group of tumours of lymphoid tissue in which there is an abnormal proliferation of cells of the lymphatic system. The literature notes a gradual increase in the incidence of this type of cancer in the whole population. The aim of the study was to evaluate whether the above tendency occurs in the head and neck area. In the years 2005-2014, at the Otolaryngology and Laryngological Oncology Department of the Upper Silesian Medical Centre in Katowice, 77 cases of lymphoma were recorded, 58 of which were analysed in terms of location, histological type, age and sex of the patient, and the presence of risk factors. The vast majority of them were non-Hodgkin's lymphomas (NHL) - 67.53%. Hodgkin's lymphomas (HL) accounted for only a small fraction of diagnoses (7.79%). In terms of histopathological types, in most cases of NHL, there occurred diffuse large B-cell lymphomas (DLBCL) - 51.92%. The most common location was the lymph nodes, representing the location of the primary lesion in more than half of the cases. As regards the extranodal location, the Waldeyer ring dominated (54.54%) along with the palatal tonsil (40.90%). There has been a significant upward trend, especially in the incidence of NHL.

  4. US-Hungarian Relations Ten Years After 1956

    Directory of Open Access Journals (Sweden)

    Tibor Glant

    2016-10-01

    Full Text Available 1966, the tenth anniversary of the 1956 Revolution, was a key year in US–Hungarian relations. Diplomatic relations were raised from the lowest to the highest level, but suspicion and tension remained. Neither side knew what to expect from the other on account of the anniversary, the Vietnam War, economic and cultural negotiations, and the fate of Cardinal Mindszenty. A traditional diplomatic historical approach is supplemented here with cultural materials to present the full scale of contacts ranging from high political issues to the visit of Hollywood movie star Kirk Douglas in Budapest. First Secretary of the Legation for Press and Cultural Affairs Edward Alexander receives special attention, because he played a crucial role in the events of 1966. As press secretary, he helped calm Hungarian fears over what American journalists might report about the anniversary, while as cultural affairs officer he worked on documenting and expanding American cultural presence in Hungary. In the latter capacity, he opened the USIA Library at the Legation, fraternized with blacklisted painters of the Zuglói Kör [‘Zugló Circle’], monitored the Hungarian stage production of My Fair Lady, and reported on the publication of American literature in Hungarian.

  5. Patch testing in Iranian patients: A ten-year experience

    Directory of Open Access Journals (Sweden)

    Davoudi Masoud

    2006-01-01

    Full Text Available Background: Allergic contact dermatitis is a common inflammatory skin disease, which may occur as a result of exposure to specific allergens. Genetic and allergen exposure variations are determinants of different frequency of sensitization in different countries. The objective of this study was to determine the frequency of sensitization to contact allergens in the Iranian patients with dermatitis. Materials and Methods: We analyzed our patch-test database in a referral skin clinic in Tehran, Iran, retrospectively. All patients patch-testing with a clinical diagnosis of contact dermatitis and/or atopic dermatitis over a 10-year period (1993 to 2002 were included. The 23-allergen European standard series (ESS screening has been used for evaluation in all the patients. Results: Data were available from a total of 222 patients. Out of them, 145 patients (65.3% showed at least one positive reaction and 34 patients (15.3% had more than two positive reactions. The five most common allergens were: nickel sulfate 50 (22.6%, cobalt chloride chloride 32 (14.5%, fragrance mix 30 (13.6%, potassium dichromate 21 (9.5% and neomycin sulfate 20 (9.0%. Contact allergy to nickel sulfate was significantly more common in females and in younger patients ( P < 0.05. Fragrance mix was the most common allergen in male patients, but there was no significant difference in its frequency between males and females. Conclusion: The ESS seems to be suitable for patch testing patients in Iran. Nickel sulfate was found to be the most common contact allergen in Iran, mostly affecting women and younger patients probably due to more exposure.

  6. Ten years of tiotropium: clinical impact and patient perspectives

    Directory of Open Access Journals (Sweden)

    Yohannes AM

    2013-03-01

    Full Text Available Abebaw M Yohannes,1 Martin J Connolly,2 Nicola A Hanania31Manchester Metropolitan University, Department of Health Professions, Manchester, UK; 2University of Auckland, Freemasons’ Department of Geriatric Medicine, Auckland, New Zealand; 3Pulmonary and Critical Care Medicine, Baylor College of Medicine, Houston, TX, USAAbstract: Tiotropium bromide is an anticholinergic agent that has gained worldwide acceptance as a first-line, once daily maintenance therapy for patients with moderate-to-severe chronic obstructive pulmonary disease. The purpose of this review is to synthesize the evidence base in the past 10 years on the development of tiotropium and its efficacy compared to other able interventions such as long-acting beta agonists (LABAs, as well as to assess its safety profile and its effects on health-related outcomes in patients with COPD. Treatment with tiotropium bromide has generally improved patients’ health-related quality of life, reduced the number of patients suffering from acute exacerbations, decreased the number of hospitalizations, improved dyspnea, and reduced adverse events compared to placebo. In the past decade, several studies have examined the safety and efficacy of tiotropium in comparison to placebo and to LABAs (salmeterol, formoterol, and indacaterol over periods ranging from 3 months to 48 months of follow-up. Head-to-head comparisons of tiotropium 18 µg (once daily with salmeterol 50 µg (twice daily in well-controlled trials demonstrated that tiotropium was superior in reducing acute exacerbation events and in improving quality of life. In a few short-term studies, indacaterol was comparable to tiotropium in its efficacy in improving health-related outcomes. Although the safety record of tiotropium has been exemplary in comparison to placebo, anticholinergic events such as dry mouth can be encountered in some patients. While the long-term safety of tiotropium when delivered in the HandiHaler® has been well

  7. Retrospective evaluation of the five-year and ten-year CSEP-Italy earthquake forecasts

    Directory of Open Access Journals (Sweden)

    Stefan Wiemer

    2010-11-01

    Full Text Available On August 1, 2009, the global Collaboratory for the Study of Earthquake Predictability (CSEP launched a prospective and comparative earthquake predictability experiment in Italy. The goal of this CSEP-Italy experiment is to test earthquake occurrence hypotheses that have been formalized as probabilistic earthquake forecasts over temporal scales that range from days to years. In the first round of forecast submissions, members of the CSEP-Italy Working Group presented 18 five-year and ten-year earthquake forecasts to the European CSEP Testing Center at ETH Zurich. We have considered here the twelve time-independent earthquake forecasts among this set, and evaluated them with respect to past seismicity data from two Italian earthquake catalogs. We present the results of the tests that measure the consistencies of the forecasts according to past observations. As well as being an evaluation of the time-independent forecasts submitted, this exercise provides insight into a number of important issues in predictability experiments with regard to the specification of the forecasts, the performance of the tests, and the trade-off between robustness of results and experiment duration. We conclude with suggestions for the design of future earthquake predictability experiments.

  8. Ten Years Back, Five Years Forward: The Data Seal of Approval

    Directory of Open Access Journals (Sweden)

    Ingrid Dillo

    2015-02-01

    Full Text Available If we want to share data, the long-term storage of those data in a trustworthy digital archive is an essential condition. Trust is the basis of storing and sharing data. That trust must be present in the various stakeholders involved. Certification of digital archives can make an important contribution to the confidence of these stakeholders in the digital archives.Ten years ago DANS was assigned the task of developing a Seal of Approval for digital data to ensure that archived data can still be found, understood and used in the future. In 2009 this Data Seal of Approval (DSA was transferred to an international body, the DSA Board, which has managed and further developed the guidelines and the peer review process ever since.The objectives of the DSA are to safeguard data, ensure high quality and guide reliable management of data for the future without requiring implementation of new standards, regulations or heavy investments. The DSA contains 16 guidelines for applying and verifying quality aspects concerning the creation, storage, use and reuse of digital data.Based on feedback from data archives that applied for a DSA and different case studies we have gained some insight into the benefits of DSA. Still, the impact of having the Seal is not easy to measure. Seal holders usually refer to qualitative benefits in the form of increased awareness of the value of their repositories to their communities, funders and publishers.Ten years down the line we can safely state that the Data Seal of Approval has proven its added value. If we try to look five years into the future, what can we expect? There are different developments: a growing interest in DSA among European research infrastructures, the collaboration between DSA and the ISCU World Data System under the umbrella of the RDA (Research Data Alliance and the European Commission is showing a growing interest in certification services.The success of DSA also provides the challenge to further

  9. Petroleum and natural gas: exploration and production in France during the last ten years

    International Nuclear Information System (INIS)

    Combaz, A.

    1993-01-01

    This paper presents petroleum and natural gas exploration in France, during the last ten years. Statistical data on production, petroleum and natural gas deposits and forecasting are also given. 4 refs., 11 figs

  10. Early Predictors of Ten-Year Course in First-Episode Psychosis

    DEFF Research Database (Denmark)

    Friis, Svein; Melle, Ingrid; Johannessen, Jan Olav

    2016-01-01

    OBJECTIVE: Identifying patients at risk of poor outcome at an early stage of illness can aid in treatment planning. This study sought to create a best-fit statistical model of known baseline and early-course risk factors to predict time in psychosis during a ten-year follow-up period after a first...... psychotic episode. METHODS: Between 1997 and 2000, 301 patients with DSM-IV nonorganic, nonaffective first-episode psychosis were recruited consecutively from catchment area-based sectors in Norway and Denmark. Specialized mental health personnel evaluated patients at baseline, three months, and one, two......, five, and ten years (N=186 at ten years). Time in psychosis was defined as time with scores ≥4 on any of the Positive and Negative Syndrome Scale items P1, P3, P5, P6, and G9. Evaluations were retrospective, based on clinical interviews and all available clinical information. During the first two years...

  11. Changing Course: Ten Years of Tracking Online Education in the United States

    Science.gov (United States)

    Allen, I. Elaine; Seaman, Jeff

    2013-01-01

    "Changing Course: Ten Years of Tracking Online Education" in the United States is the tenth annual report on the state of online learning in U.S. higher education. The survey is designed, administered and analyzed by the Babson Survey Research Group. Data collection is conducted in partnership with the College Board. This year's study, like those…

  12. DITTY - a computer program for calculating population dose integrated over ten thousand years

    International Nuclear Information System (INIS)

    Napier, B.A.; Peloquin, R.A.; Strenge, D.L.

    1986-03-01

    The computer program DITTY (Dose Integrated Over Ten Thousand Years) was developed to determine the collective dose from long term nuclear waste disposal sites resulting from the ground-water pathways. DITTY estimates the time integral of collective dose over a ten-thousand-year period for time-variant radionuclide releases to surface waters, wells, or the atmosphere. This document includes the following information on DITTY: a description of the mathematical models, program designs, data file requirements, input preparation, output interpretations, sample problems, and program-generated diagnostic messages

  13. DITTY - a computer program for calculating population dose integrated over ten thousand years

    Energy Technology Data Exchange (ETDEWEB)

    Napier, B.A.; Peloquin, R.A.; Strenge, D.L.

    1986-03-01

    The computer program DITTY (Dose Integrated Over Ten Thousand Years) was developed to determine the collective dose from long term nuclear waste disposal sites resulting from the ground-water pathways. DITTY estimates the time integral of collective dose over a ten-thousand-year period for time-variant radionuclide releases to surface waters, wells, or the atmosphere. This document includes the following information on DITTY: a description of the mathematical models, program designs, data file requirements, input preparation, output interpretations, sample problems, and program-generated diagnostic messages.

  14. Indirect composite restorations luted with two different procedures: A ten years follow up clinical trial

    Science.gov (United States)

    Preti, Alessandro; Vano, Michele; Derchi, Giacomo; Mangani, Francesco; Cerutti, Antonio

    2015-01-01

    Objectives: The aim of this clinical trial was to evaluate posterior indirect composite resin restoration ten years after placement luted with two different procedures. Study Design: In 23 patients 22 inlays/onlays (Group A) were luted using a dual-cured resin composite cement and 26 inlays/onlays (Group B) were luted using a light cured resin composite for a total of 48 Class I and Class II indirect composite resin inlays and onlays. The restorations were evaluated at 2 time points: 1) one week after placement (baseline evaluation) and 2) ten years after placement using the modified USPHS criteria. The Mann-Whitney and the Wilcoxon tests were used to examine the difference between the results of the baseline and 10 years evaluation for each criteria. Results: Numerical but not statistically significant differences were noted on any of the recorded clinical parameters (p>0.05) between the inlay/onlays of Group A and Group B. 91% and 94 % of Group A and B respectively were rated as clinically acceptable in all the evaluated criteria ten years after clinical function. Conclusions: Within the limits of the study the results showed after ten years of function a comparable clinical performance of indirect composite resin inlays/onlays placed with a light cure or dual cure luting procedures. Key words:Light curing composite, dual curing composite, indirect composite restoration, inlays/onlays, clinical trial. PMID:25810842

  15. Self-esteem and depression: ten year follow-up of mothers and offspring.

    Science.gov (United States)

    Miller, L; Warner, V; Wickramaratne, P; Weissman, M

    1999-01-01

    The association between maternal bonding style, offspring low self-esteem and offspring depression status was assessed by maternal depression status. Sixty mothers and 137 offspring were independently assessed over the course of a ten year follow-up study. Assessments included the Schedule for Affective Disorders and Schizophrenia (SADS-LA), Schedule for Affective Disorders and Schizophrenia for School-Aged Children (K-SADS), the Coopersmith Self-Esteem Inventory (CSEI) and the Parental Bonding Instrument (PBI). Among daughters of mothers with a history of depression, maternal affectionless-control was associated with daughter low self-esteem which was associated with daughter depression at ten year follow-up. Among daughters of mothers without a history of depression, maternal affectionless-control was not associated with daughter low self-esteem, which was not associated with daughter depression at ten year follow-up but which was associated with a history of childhood depression. None of these associations were found to be significant among sons. As self-esteem was not measured at ten year follow-up, among offspring the stability of self-esteem could not be assessed, nor could the association between adult self-esteem and adult depression. Clinical presentation of low self-esteem in girls should be assessed in the context of maternal depression status.

  16. A Ten-year Period of Daily Sea Surface Temperature at a Coastal ...

    African Journals Online (AJOL)

    In summer, the tropical cyclones are the major cause of short term variability, with sudden drops of SST than can exceed 2°C within a few hours. The annual cycle of SST is closely associated with that of wind stress, with a lagged response of about 2 months of SST to wind forcing. Throughout the 'ten-year period' covered ...

  17. Transverse patella fracture in a ten year old boy: case report ...

    African Journals Online (AJOL)

    ... an uncommon pattern. We report a case of a transverse patella fracture in a ten year old boy. He presented with inability to actively extend his left knee, two months after a fall. On evaluation he was found to have a transverse fracture of his left patella. This was treated by tension band wiring. EAOJ; Vol. 7: September 2013 ...

  18. Diseases of poultry in Akure, Nigeria: a ten year analysis of clinical ...

    African Journals Online (AJOL)

    An analysis of poultry diseases diagnosed at the avian clinic of Veterinary Hospital of the Ministry of Agriculture and Natural Resources, Akure, Ondo-State, was carried out using data from 22,927 cases reported at the clinic over a period of ten years. The commonest diseases reported were Newcastle, 9.8%, chronic ...

  19. Ten years after the Jali Commission Assessing the state of South ...

    African Journals Online (AJOL)

    Ten years have lapsed since the Jali Commission's final report became publicly available, and it is therefore an opportune time to assess the state of South Africa's prison system. The Jali Commission was appointed when it became clear that the state had lost control of the Department of Correctional Services (DCS).

  20. The HADES project - ten years of civil engineering practice in a plastic clay formation

    International Nuclear Information System (INIS)

    De Bruyn, D.J.; Neerdael, B.A.

    1991-01-01

    Various civil engineering works and underground experiments have been performed during the last ten years in Belgium to assess the technical feasibility of building a repository for high level waste (HLW) disposal in a plastic clay formation; they lead to the conclusion that the construction of tunnels for this purpose may now be considered as technically and economically feasible. (author)

  1. Mathematical Skills in Undergraduate Students. A Ten-Year Survey of a Plant Physiology Course

    Science.gov (United States)

    Llamas, A.; Vila, F.; Sanz, A.

    2012-01-01

    In the health and life sciences and many other scientific disciplines, problem solving depends on mathematical skills. However, significant deficiencies are commonly found in this regard in undergraduate students. In an attempt to understand the underlying causes, and to improve students' performances, this article describes a ten-year survey…

  2. The Decline of Print: Ten Years of Print Serial Use in a Small Academic Medical Library

    Science.gov (United States)

    Rosati, Karen Thompson

    2006-01-01

    Tracking use of print journals over a ten-year period has allowed The University of South Carolina (USC) School of Medicine Library an essential tool for more accurate collection development, for both print and electronic selection. This lengthy study has provided usage statistics for purchasing decisions regarding electronic subscriptions still…

  3. Review Paper: Hydatidiform mole in Calabar, Nigeria: a ten-year ...

    African Journals Online (AJOL)

    A total of 79 patients who were managed for hydatidiform mole in University of Calabar Teaching Hospital over ten years were reviewed with the aims of establishing the incidence and assessing outcome of management. Relevant information was obtained from the case files and analyzed. The incidence of 1 in 187 of total ...

  4. A Ten-Year Review of Childhood Renal Admissions into the Lagos ...

    African Journals Online (AJOL)

    A Ten-Year Review of Childhood Renal Admissions into the Lagos University Teaching Hospital, Nigeria. ... Wilms Tumor (15.3%), acute renal failure (7.4%), urinary tract infection (4.9%), posterior urethral valves 3.4%), and chronic renal failure (0.5%) in order of ranking. Mortality was 17.7% and deaths were mainly from ...

  5. Survival and vigour of ultra-dry seeds after ten years of hermetic storage

    NARCIS (Netherlands)

    Hong, T.D.; Ellis, R.H.; Astley, D.; Pinnegar, A.E.; Groot, S.P.C.; Kraak, H.L.

    2005-01-01

    Seeds of carrot, groundnut, lettuce, oilseed rape and onion were stored hermetically in laminated aluminium foil packets in four environments (dry or ultra-dry moisture contents combined factorially with temperatures of 20 degrees C or -20 degrees C), replicated at several sites. After ten years'

  6. "Ten Years On": Making Children Visible in Teacher Education and Ways of Reading Video

    Science.gov (United States)

    Burke, Catherine; Cunningham, Peter

    2011-01-01

    "Ten Years On" is a 30-minute video documentary discovered in the course of researching progressive primary education, school architecture and pedagogy. It was locally produced for professional rather than commercial use at a significant historical moment for educational politics and primary practice. Here, we explore the possibilities…

  7. 50 years ago: the Nuremberg Doctors' Tribunal. Part 4: Nazi medicine's relevance today.

    Science.gov (United States)

    Ernst, E

    1997-01-01

    The final part of this series attempts to evaluate the relevance of Nazi medicine for doctors today. Euthanasia, informed consent, the conflict of interests of the individual versus those of society and racism were as prominent themes of Nazi medicine as they are today. It would be foolish not to learn from experiences of the past. Nazi medicine can therefore never be an irrelevant subject of the days gone by.

  8. Do Estrogens improve bone mass in osteoporotic women over ten years of menopause

    Directory of Open Access Journals (Sweden)

    Vera Lucia Szejnfeld

    Full Text Available A retrospective analysis of 24 patients with established osteoporosis and with ten or more years of menopause treated with conjugated estrogen, progesterone and calcium followed for one year has been performed. Treated women received 0.625 mg/day of conjugated estrogen from day 1 to 25, 5 mg/day of medroxiprogesterone from day 13 to 25, of each cycle, plus calcium (500 - 1000 mg/day, during one year (12 cycles. As control group was used 18 age-matched that received only calcium (500 a 1000 mg/day. All patients had at least two dual-photon spine and proximal femur (neck, Ward's triangle and trocanter densities measurements performed 12 months apart. Estrogen treatment was associated with increased bone mineral density at spine and trocanter. Control group did not present any statistically change after one year in any site studied. We concluded that women with ten or more years of menopause and established osteoporosis treated with replacement hormonal therapy and calcium results in improvement of bone mineral density. These data support that women with ten or more years of menopause respond to estrogen replacement therapy with absolute increments in bone density similar to those seen in younger women, in the early menopause.

  9. How did General Surgery Department of a Training Hospital Change in Ten Years?

    Directory of Open Access Journals (Sweden)

    Zafer Ergül

    2012-07-01

    Full Text Available  Aim: To investigate the changes in a training hospital’s surgical patient profile in ten years. To delineate the effects of the transfer of Social Security Institution Hospitals to the Ministry of Health on this process. Material and Method: Ten-year apart, two-year periods were selected and all elective and emergency cases were retrospectively searched. In between periods, the hospital was transferred from Social Security Institution Hospital to the Ministry of Health and then became a trauma center. The indications, techniques, the number of performed surgeries, and the patient related factors were compared. The ratio of the number emergency cases and the number of cases performed by residents in training to the total number of cases were investigated. Results: The number of elective and emergent operations during the former and the latter periods were 2668 and 2041, respectively. The percentage of the decrease was 23.5%. After ten years, the patients were younger, more commonly male, emergency cases were more common, and operations performed primarily by the residents in training were less frequent than the former period (p<0,05. Oncological surgery of stomach, colon-rectum, breast, thyroid and primary-metastatic-malign carcinoma were more frequent during former period whereas urgent operations except peptic ulcer perforation and upper gastrointestinal bleeding and benign anorectal diseases were more common during later period (p<0,05. Discussion: The comparison revealed a significant decrease in the number of operations in ten years. The number of oncological patients increased whereas the number of emergency cases declined. The changes were thought to be related more to the transition in health and becoming a trauma center than to major developments in the country and the world.

  10. Frequency of diabetic retinopathy in patients after ten years of diagnosis of type 2 diabetes mellitus

    International Nuclear Information System (INIS)

    Shaikh, M.A.; Yakta, D.E.

    2010-01-01

    Background: Diabetic retinopathy is one of the most common and serious complications of type 2 diabetes mellitus and a leading cause of blindness not only in Pakistan but also worldwide. So we conducted this study to record the frequency of diabetic retinopathy in known diabetic patients ten years after diagnosis of type 2 diabetes mellitus. Methods: The study was conducted at Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan for a period of 1 year from January 2008 to January 2010. The study group comprised of 200 patients of type 2 diabetes mellitus attending the medical clinic. All patients who were diagnosed as type 2 diabetes mellitus since ten years duration were included in the study. Retinopathy was graded into background, pre proliferative and proliferative retinopathy. Type 2 diabetes was diagnosed using the WHO criteria. Statistical analysis was carried out using the SPSS-11. Results: Diabetic retinopathy was found in 25.5% of the total Type 2 patients after ten years of diagnosis, and of these 4% of patients had proliferative retinopathy. Conclusion: Type 2 diabetic patients should be screened as early as possible to prevent permanent visual loss by timely management of diabetic retinopathy because diabetes is one of most common preventable cause of blindness in the world. (author)

  11. Analysis of Personal Dosimetry for Nuclear Medicine Staff in Ten-Year Period

    International Nuclear Information System (INIS)

    Poropat, M.; Dodig, D.; Ciglar, M.; Tezak, S.

    2011-01-01

    The aim of this study was to assess the value of personal dosimetry for nuclear medicine personnel in our department in a ten-year period. We have analyzed personal doses for 80 employees in nuclear medicine in a ten year period that we divided into two five year periods (from 2000 to 2004 and from 2005 to 2009). The personnel was dived into 8 groups according to their working assignments due to different radiation exposure from various radioisotopes in different wards in nuclear medicine: nuclear medicine specialists, technologists in scintigraphy ward, personnel of physics ward, ward for radiochemistry and radioimmunology, clinical ward and ultrasound ward, cleaning personnel, administrative personnel. We have compared average dose per person in particular ward in two five year periods. All doses for all personnel were in the permissible limits prescribed by the authorities. Higher average dose per person in a first five year period was detected in two wards, scintigraphy ward and ward for radiochemistry and radioimmunology due to the nature of their working assignments (preparation and application of radiopharmaceuticals, contact with patients who have received radiopharmaceutical). The decrease in the average dose per person was noticed in a second five-year period, especially in the wards with personnel that had no prior education in ionizing radiation protection. The decrease of dose was from 7.5 % to 84.2 %. We think that the decrease of average dose per person in a second five-year period was not only the result of the increased personal protection measures but also the result of continuing education of nuclear medicine personnel that is obligatory by the Law for ionizing radiation protection from year 1999, and the results from a ten-year period show its positive effect on radiation protection. (author)

  12. Ten-Year Outcome Comparison of the Anatomical Graduated Component and Vanguard Total Knee Arthroplasty Systems.

    Science.gov (United States)

    Faris, Philip M; Ritter, Merrill A; Davis, Kenneth E; Priscu, Hana M

    2015-10-01

    The development of a new total knee system as a successor prosthesis in total knee arthroplasty (TKA) requires clinical outcome improvement. 10,843 TKAs were performed of which 9169 utilized the Anatomical Graduated Component (AGC) and 1674 utilized the Vanguard prosthesis (both Biomet, Warsaw, IN). Survival rates at ten years postoperatively for the AGC and Vanguard were 98.7% and 98.4% (P=.4897) respectively. The top reasons for component failure were loosening (AGC: 0.29%, Vanguard: 0.30%), polyethylene wear, and instability (AGC: 0.13%, Vanguard: 0.12%). These results reveal similar outcomes in both designs, with relatively few revisions and high survival rates at ten years postoperatively. This abstract offers data concerning the usefulness of the Vanguard Total Knee System as a successor to the Anatomical Graduated Component. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. A ten-year review of chronic cor pulmonale secondary to respiratory diseases in Ghana.

    Science.gov (United States)

    Oduro-Boatey, Collins; Adzosii, Della

    2017-10-01

    Chronic cor pulmonale is defined as right ventricular failure secondary to pulmonary hypertension. Our study reviewed all cases of chronic cor pulmonale secondary to respiratory diseases in a ten-year period (2004-20014) in the Department of Child Health, Korle-Bu Teaching Hospital, Ghana. Nine cases of chronic cor pulmonale were recorded during the period. The age range was 1-9 years (average age = 3 years). Obstructive sleep apnoea secondary to adenoid hypertrophy was the commonest cause of pulmonary hypertension.

  14. 226Ra intake in the population from Bucharest during the past ten years

    International Nuclear Information System (INIS)

    Toader, M.; Vasilache, R.A.; Tomulescu, V.

    1998-01-01

    During 1986-1996 the content of several radionuclides, including 226 Ra, in the basic foodstuffs and in drinking water was determined. Based on these data and on the data concerning the constituents of the diet in Romania, the 226 Ra intake by the population of Bucharest was estimated for the last ten years, and the doses due to this intake were calculated. The results are presented in graphs and tables, and some general conclusions are drawn. (A.K.)

  15. Ten Years of Monitoring 3C 273 with XMM–Newton Liu Liu ...

    Indian Academy of Sciences (India)

    Abstract. We present ten years optical/UV/X-ray observations of 3C. 273 performed using XMM–Newton between 2000 and 2009. The short- time scale variability behaviour of the soft and hard X-ray light curves may suggest different origins of the soft/hard X-ray emissions. We fit well the 0.2–10 keV X-ray spectrum with a ...

  16. Ten Years of Monitoring 3C 273 with XMM–Newton

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... We present ten years optical/UV/X-ray observations of 3C 273 performed using XMM–Newton between 2000 and 2009. The short-time scale variability behaviour of the soft and hard X-ray light curves may suggest different origins of the soft/hard X-ray emissions. We fit well the 0.2–10 keV X-ray spectrum ...

  17. A prospective ten-year follow-up of patients with chronic urticaria.

    Science.gov (United States)

    Dionigi, P C L; Menezes, M C S; Forte, W C N

    2016-01-01

    Chronic urticaria can be the initial clinical presentation of a number of different diseases. The objective of the present study was to report the associated diseases during a ten-year clinical-laboratory follow-up in patients with an initial diagnosis of chronic spontaneous urticaria (CSU) of unknown cause. A prospective, longitudinal cohort study with a ten-year clinical-laboratory follow-up was conducted. Patients with a history of urticarial plaques of over six weeks presenting as the only clinical symptom were selected. Individuals with other clinical conditions, urticaria of known causes or chronic physical urticaria were excluded. The following tests were initially performed: haemogram, urine type I, stool parasite exam and sedimentation rate. The following exams were ordered during follow-up: PPD; urine culture; serology tests; antithyroid and antinuclear antibodies, rheumatoid factor, lupus anticoagulant; thyroid hormones; serum immunoglobulin; paranasal sinus and thorax radiographs; testing for BK and Helicobacter pylori; and prick tests. Infections were diagnosed in 29% of patients (syphilis, parasitosis, H. pylori, urinary infection, tuberculosis, hepatitis B and C); autoimmune diseases in 21% (thyroiditis, rheumatoid arthritis and antiphospholipid antibody syndrome); primary immunodeficiencies in 4% (IgA and IgG2 deficiencies); and chronic myeloid leukaemia in 1%. At ten-years of follow-up, the urticaria diagnosis was CSU of unknown cause in 45% of the cases. This ten-year clinical-laboratory follow-up of 100 individuals with chronic urticaria as the initial diagnosis revealed the presence of associated diseases in over half of the cases. The most prevalent diseases were infections and autoimmune diseases besides primary immunodeficiencies and blood diseases. Copyright © 2016 SEICAP. Published by Elsevier España, S.L.U. All rights reserved.

  18. Campylobacter Antimicrobial Resistance in Peru: A Ten-year Observational Study

    Science.gov (United States)

    2012-08-16

    Miller WG, Konkel ME: Differentiation of Campylobacter coli, Campylobacter jejuni, Campylobacter lari, and Campylobacter upsaliensis by a multiplex PCR ...van Pelt W, Wagenaar JA, Kuijper EJ: Inaccuracy of routine susceptibility tests for detection of erythromycin resistance of Campylobacter jejuni...available soon. Campylobacter antimicrobial resistance in Peru: a ten-year observational study BMC Infectious Diseases 2012, 12:193 doi:10.1186/1471-2334-12

  19. Ten-year utilization of the Oregon State University TRIGA Reactor (OSTR)

    International Nuclear Information System (INIS)

    Ringle, John C.; Anderson, Terrance V.; Johnson, Arthur G.

    1978-01-01

    The Oregon State University TRIGA Reactor (OSTR) has been used heavily throughout the past ten years to accommodate exclusively university research, teaching, and training efforts. Averages for the past nine years show that the OSTR use time has been as follows: 14% for academic and special training courses; 44% for OSU research projects; 6% for non-OSU research projects; 2% for demonstrations for tours; and 34% for reactor maintenance, calibrations, inspections, etc. The OSTR has operated an average of 25.4 hours per week during this nine-year period. Each year, about 20 academic courses and 30 different research projects use the OSTR. Visitors to the facility average about 1,500 per year. No commercial radiations or services have been performed at the OSTR during this period. Special operator training courses are given at the OSTR at the rate of at least one per year. (author)

  20. Ten year experience with antiretroviral treatment in Cambodia: Trends in patient characteristics and treatment outcomes.

    Directory of Open Access Journals (Sweden)

    Phirum Lay

    Full Text Available Although HIV disease stage at ART initiation critically determines ART outcomes, few reports have longitudinally monitored this within Asia. Using prospectively collected data from a large ART program at Sihanouk Hospital Center of Hope in Cambodia, we report on the change in patient characteristics and outcomes over a ten-year period.We conducted a retrospective analysis including all adults (≥ 18 years old starting ART from March 2003-March 2013 in a non-governmental hospital in Phnom Penh, Cambodia. The cumulative incidence of death, lost to follow-up (LTFU, attrition (death or LTFU and first line treatment failure were calculated using Kaplan-Meier methods. Independent risk factors for these outcomes were determined using Cox regression modeling.Over the ten-year period, 3581 patients initiated ART with a median follow-up time of 4.8 years (IQR 2.8-7.2. The median age was 35 years (IQR 30-41, 54% were female. The median CD4 count at ART initiation increased from 22 cells/μL (IQR 4-129 in 2003 to 218 (IQR 57-302 in 2013. Over the 10 year period, a total of 282 (7.9% individuals died and 433 (12.1% were defined LTFU. Program attrition (died or LTFU was 11.1% (95% CI: 10.1%- 12.4% at one year, 16.3% (95% CI: 15.1%-17.6% at three years, 19.8% (95% CI: 18.5%-21.2% at five years and 23.3% (95% CI: 21.6-25.1 at ten years. Male sex and low baseline body mass index (BMI were associated with increased attrition. Factors independently associated with mortality included a low baseline CD4 count, older age, male sex, low baseline BMI and hepatitis B co-infection. Individuals aged above 40 years old had an increased risk of mortality but were less likely to LTFU. There were a total of 137 individuals with first line ART failure starting second line treatment. The probability of first line failure was estimated at 2.8% (95% CI: 2.3%-3.4% at 3 years, 4.6% (95% CI: 3.9%-5.5% at 5 years and 7.8% (95% CI 4.8%-12.5% at ten years of ART. The probability was

  1. Idaho National Laboratory 2013-2022 Ten-Year Site Plan

    Energy Technology Data Exchange (ETDEWEB)

    Calvin Ozaki; Sheryl L. Morton; Elizabeth A. Connell; William T. Buyers; Craig L. Jacobson; Charles T. Mullen; Christopher P. Ischay; Ernest L. Fossum; Robert D. Logan

    2011-06-01

    The Idaho National Laboratory (INL) Ten-Year Site Plan (TYSP) describes the strategy for accomplishing the long-term objective of transforming the laboratory to meet Department of Energy (DOE) national nuclear research and development (R&D) goals, as outlined in DOE strategic plans. The plan links R&D mission goals and INL core capabilities with infrastructure requirements (single- and multi-program), establishs the 10-year end-state vision for INL complexes, and identifies and prioritizes infrastructure needs and capability gaps. The TYSP serves as the basis for documenting and justifying infrastructure investments proposed as part of the FY 2013 budget formulation process.

  2. Ten years of democracy: attitudes and identity among some South African school children

    Directory of Open Access Journals (Sweden)

    Dyers, Charlyn

    2004-12-01

    Full Text Available Ten years into South Africa’s democracy, how do school children feel about themselves as part of specific groups, and what is the role of language in their socio-cultural identities? This paper looks at the ways in which two groups of fourteen-year-old Xhosa-speaking and mixed-race ‘Coloured’ South African secondary school learners in a new housing area near Cape Town negotiate their identities through language in a context of rapid social change. It analyses their beliefs and attitudes about the languages and speech communities to which they are exposed.

  3. Ten Years of the Sino-European Strategic Partnership: Achievements and Problems

    Directory of Open Access Journals (Sweden)

    Mingjin Wang

    2013-12-01

    Full Text Available Ten years after the establishment of the strategic partnership between China and the EU, this relationship has continued to flourish. However, publicly they have often been at odds, and even created doubts about the real existence of the comprehensive strategic partnership. The drawbacks of this relationship in recent years are mainly caused by the increased competitiveness in economy and trade, and the outbreak of quarrels concerning human rights and other areas. Since Sino-EU relations are very important for both parties and the world in general, both sides should find ways to control their conflicts and thus pave the way for their comprehensive strategic partnerships to further flourish.

  4. A ten year audit of maternal mortality: Millennium development still a distant goal

    Directory of Open Access Journals (Sweden)

    Anshuja Singla

    2017-01-01

    Full Text Available Objective: To assess various causes of maternal mortality over a ten year period Design: Retrospective audit of hospital case records Setting: Tertiary care hospital Population: Pregnant women who expired in the premises of GTB Hospital. Materials and Methods: A retrospective audit of case records of maternal deaths was conducted for a ten year period (January 2005 to December 2014. Results: There were a total of 647 maternal deaths out of 1,16,641 live births. Sixty-eight percent (n = 445 of women were aged 21-30 years, while 10.5% (n = 68 were <20 years of age. The most common direct causes of maternal mortality were preeclampsia/eclampsia in 24.4% (n = 158, obstetric hemorrhage in 19.1% (n = 124 and puerperal sepsis in 14.5% (n = 94. With regards to indirect causes, anemia accounted for 15.3% (n = 99 mortality. There was only 1 (0.1% mortality because of HIV/AIDS. Other notable causes of maternal mortality were infective hepatitis in 7.1% (n = 46. Tuberculosis, that is a disease of tropical countries, accounted for 3.0% (n = 20 of the total deaths. Conclusion: High maternal mortality in GTB hospital can be due to it being a tertiary hospital with referrals from all neighbouring states. Accessible antenatal care can help prevent these maternal deaths. Female education can be of immense help in dealing with the problem and improving the utilization of public health facilities.

  5. Psychoanalysis today

    OpenAIRE

    FONAGY, PETER

    2003-01-01

    The paper discusses the precarious position of psychoanalysis, a therapeutic approach which historically has defined itself by freedom from constraint and counted treatment length not in terms of number of sessions but in terms of years, in today's era of empirically validated treatments and brief structured interventions. The evidence that exists for the effectiveness of psychoanalysis as a treatment for psychological disorder is reviewed. The evidence base is significant a...

  6. Characteristics of written syntax in ten-year-old fourth-graders

    Directory of Open Access Journals (Sweden)

    Ivanović Maja

    2015-01-01

    Full Text Available The main purpose of this study is to present an inventory of different types of syntactic constructions found in written discourse of ten-year-old fourth graders, that is, to examine the existing variations in text syntactic structures which were produced by fourth graders. Written text corpus was collected from 88 fourth graders from Belgrade. In three different sessions, students composed three texts in three different genres: narrative, expository, and argumentative. Thematic and genre versatility enriched the corpus and created favourable conditions for elicitation of different types of syntactic constructions. Different quantitative and qualitative characteristics of texts from the database were taken into account and analysed: the mean length of text measured by the number of words, the number of utterances, and the mean length of utterance measured by the number of words and clauses, as well as the presence of various types of syntactic constructions (kernel, simple, compound, complex and complex-compound sentences. The frequency of appearance of each of these was then established. The results provide an insight into the average length of texts and sentences produced by the fourth-grade primary school pupils, as well as into the means used to produce them (the kind of sentences they form. The results are much more valuable because they are concerned with examining the syntax in children who are native speakers of Serbian. They also show that in ten-year-olds’ texts all the analysed types of sentence structure may appear, but the use frequency varies. Besides providing an inventory of syntactic attainments in written production of ten-year-old children, the research presented a new insight into their syntactic competence. [Projekat Ministarstva nauke Republike Srbije, br. OI 178002: Jezici i kulture u vremenu i prostoru i br. OI 179068: Evaluacija tretmana stečenih poremećaja govora i jezika

  7. CYSTINURIA - A TEN-YEAR FOLLOW-UP OF THE PATIENTS

    Directory of Open Access Journals (Sweden)

    Anđelka Slavković

    2001-09-01

    Full Text Available In the period from 1991 to 2001 there were four patients followed up who suffered from cystinuria and cystine calcinosis. The therapy consisting of the cystine dilution in the urine by a great taking-in of liquids and the urine alkalization was combined with alphamercaptopropione glycine and captoprile that bind cystine as well as a respective diet. Alphamercaptopropione glycine leads to the reduction of the already-formed calculus and their easier treatment in the case of a possible need for extracorporeal lithotripsy (ESWEL. During the ten-year follow-up of a small series of patients there were no complications related to the medicament treatment.

  8. Plant and equipment division laboratory services series: a ten-year building-maintenance cost history

    Energy Technology Data Exchange (ETDEWEB)

    Keesee, H.F.

    1976-09-01

    Maintaining a multifacility national laboratory in a safe, reliable condition is a complex management responsibility in terms of budgets, costs, and proper utilization of personnel and material resources. Increasing wage rates and material costs, combined with decreased budgets and aging facilities, create unusual challenges to maintenance managers. A ten-year history of building-maintenance costs, a brief description of the maintenance program, analyses of personnel requirements, cost increase indexes, unit costs, cost controls, procedures, and a brief discussion of alterations and improvements are presented.

  9. Colorectal carcinoma in a ten-year-old girl: A case report

    Directory of Open Access Journals (Sweden)

    Sarbani Chattopadhyay

    2012-01-01

    Full Text Available Colorectal carcinoma is very rare in childhood. In this case report, we depict a ten-year-old girl who presented with features of intestinal obstruction which turned out to be due to poorly differentiated mucin secreting adenocarcinoma of descending colon. Only increased awareness of this malignancy in this age-group and a high index of suspicion can help when a child complains of persistent pain of abdomen, altered bowel habits or rectal bleeding, and may provide diagnosis at an earlier stage, thereby improving the prognosis.

  10. Ten years of cryo-magnetic W7-X test facility construction and operation

    International Nuclear Information System (INIS)

    Renard, B.; Dispau, G.; Donati, A.; Genini, L.; Gournay, J.F.; Kuster, O.; Molinie, F.; Schild, T.; Touzery, R.; Vieillard, L.; Walter, C.

    2011-01-01

    The construction, commissioning, and operation phases of the W7-X cryo-magnetic test facility in CEA Saclay lasted ten years. The large diversity of equipments called, specialties involved and problems solved attest the expertise that was required to operate the test facility and test the coils. Nearly one hundred cryogenic tests were performed on the seventy W7-X coils, at a rate always increasing, using two cryostats each holding two coils. This paper presents the test facility and its operation first, the cryogenic difficulties that were confronted with their solutions, the electro-magnetic difficulties encountered along with corrective actions, and finally the instrumentation and data acquisition aspects. (authors)

  11. Ten years of forensic odontology: a report from the Department of Forensic Odontology, Stockholm, Sweden.

    Science.gov (United States)

    Teivens, A; Mornstad, H

    1992-12-01

    The practical activities of the Department of Forensic Odontology at the National Board for Forensic Medicine in Stockholm, Sweden, have been reviewed over a ten year period (1980-1989). The number of cases has increased from 72 in 1980 to 278 in 1989, and a total of 1402 tasks have been carried out. Seventy-five per cent of the cases have concerned identification of single individuals, 14% have involved the National Register of Missing Persons with the remaining cases being age determination (34), bite marks (27), oral examination after criminal assault (69), examination of skeletal remains, dentures, restorative materials (33) and written reports to be presented at court (159).

  12. Plant and equipment division laboratory services series: a ten-year building-maintenance cost history

    International Nuclear Information System (INIS)

    Keesee, H.F.

    1976-09-01

    Maintaining a multifacility national laboratory in a safe, reliable condition is a complex management responsibility in terms of budgets, costs, and proper utilization of personnel and material resources. Increasing wage rates and material costs, combined with decreased budgets and aging facilities, create unusual challenges to maintenance managers. A ten-year history of building-maintenance costs, a brief description of the maintenance program, analyses of personnel requirements, cost increase indexes, unit costs, cost controls, procedures, and a brief discussion of alterations and improvements are presented

  13. Ten years of experience with transgastric necrosectomy for walled-off necrosis in acute pancreatitis

    DEFF Research Database (Denmark)

    Busse, Malene Just; Ainsworth, Alan Patrick

    2015-01-01

    INTRODUCTION: The aim of this study was to report our results with open transgastric necrosectomy for walled-off necrosis in acute pancreatitis over a period of ten years. METHODS: Patients operated at the department from 2003 until 2012 were studied retrospectively. RESULTS: A total of 50 patients......: Acute pancreatitis with walled-off necrosis has a high mortality rate. Need for additional therapy following necrosectomy was associated with fatal outcome. Endocrine and exocrine insufficiency was often seen at follow-up. FUNDING: none. TRIAL REGISTRATION: The study was approved by the Danish Data...

  14. Acute lower abdominal pain caused by adnexal torsion in a ten-year-old girl

    DEFF Research Database (Denmark)

    Steinthorsdottir, Kristin Julia; Hansen, Lars Folmer; Bisgaard, Thue

    2014-01-01

    A ten-year-old girl presented with four days of lower abdominal pain. A diagnostic laparoscopy on the suspicion of acute appendicitis revealed left-sided adnexal torsion. The cyanotic ovary was detorsed and recovered. At three-month follow-up there were no clinical or ultrasonic signs of pathology....... The clinical presentation of adnexal torsion is unspecific and mimics several differential diagnosis. Adnexal torsion is a rare condition, especially in pre-pubertal girls. However, it must still be kept in mind when evaluating girls regardless of age with lower abdominal pain....

  15. Educational virtual environments: A ten-year review of empirical research (1999-2009)

    DEFF Research Database (Denmark)

    Mikropoulos, Tassos; Natsis, Antonios

    2011-01-01

    This study is a ten-year critical review of empirical research on the educational applications of Virtual Reality (VR). Results show that although the majority of the 53 reviewed articles refer to science and mathematics, researchers from social sciences also seem to appreciate the educational...... value of VR and incorporate their learning goals in Educational Virtual Environments (EVEs). Although VR supports multisensory interaction channels, visual representations predominate. Few are the studies that incorporate intuitive interactivity, indicating a research trend in this direction. Few...

  16. Comparison of the refractive error changes among young children in ten years interval

    Directory of Open Access Journals (Sweden)

    Hai-Yan Li

    2013-07-01

    Full Text Available AIM: To compare the optometric examination results of myopic young children between those diagnosed in the period from 1998 to 2000 and those diagnosed in the period from 2008 to 2010; and to find out the causes of myopia and factors that worsen the condition, and suggest methods of its prevention and treatment.METHODS: This study was a retrospective case study. We randomly selected sample from out-patient department register of cases and divided them into two main groups, ‘ten year before group'(TYBG(1998/2000 year casesand ‘ten years later group'(2008/2010 year cases(TYLG. Each group was further subdivided into three sub-groups by age: under-six years old children group(CG, seven-twelve years old primary-school group(PSGand thirteen-eighteen years old middle-school group(MSG. The optometric examination results were statistically analyzed.RESULTS: The difference of the mean dioptre between the TYBG and TYLG was strongly statistically significant, also forward-lead trend of age when children suffered from myopia was found(P0.01. There was a significant increase of dioptre among PSG and MSG in TYLG compared to TYBG(PCONCLUSION: Our study shows that the age of getting myopia was forward lead, the dioptre increases by 1.00 degree and the prevalence of myopia is increasing gradually. This situation may due to the modern life style and changes of living standard of the population. Therefore, prevention of myopia should concentrate more on younger children at kindergarten and primary school stage students.

  17. Successful weight maintainers among young adults-A ten-year prospective population study.

    Science.gov (United States)

    Kärkkäinen, Ulla; Mustelin, Linda; Raevuori, Anu; Kaprio, Jaakko; Keski-Rahkonen, Anna

    2018-03-07

    To assess factors associated with successful weight maintenance over ten years in a prospective general population sample of young adults. Our study comprised 2452 women and 2227 men born in 1975-1979 (mean age at baseline 24 years, attrition 27.1%). Weight maintenance was defined as weight maintained within ±5% of baseline body mass index (BMI). We examined the role of various sociodemographic and lifestyle factors in successful weight maintenance. Relatively few young adults were able to maintain their weight over ten years (28.6% of women vs. 23.0% of men); net weight loss was uncommon (7.5% and 3.8%). Most participants gained weight (mean annual weight gain was 0.9 kg in women and 1.0 kg in men). Among women, exercise was associated with successful weight maintenance, but having two or more children, frequent use of sweet drinks, irregular eating, history of dieting (intentional weight loss) and low life satisfaction were associated with weight gain. Among men, higher baseline BMI and higher education were associated with successful weight maintenance, whereas irregular eating, history of dieting and smoking were associated with weight gain. Only about a quarter of young adults were able to resist weight gain. Regular eating and having no history of dieting were associated with successful weight maintenance in young women and men. Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. Mercury Studies around the Mediterranean Sea Basin: Ten years of Measurements and Modeling results

    Directory of Open Access Journals (Sweden)

    Sprovieri F.

    2013-04-01

    Full Text Available Only a few years ago the presence of Reactive Gaseous Mercury (RGM was believed to be almost exclusively the result of anthropogenic emissions and that sustained high RGM concentrations in the MBL were not considered likely. During the past ten years, an in-depth investigation was carried out in the Marine Boundary Layer (MBL of the Mediterranean Sea to quantify and possibly explain spatial and temporal patterns of Hg-species concentrations. This paper provides an overview of modeling results and atmospheric measurements performed during several cruise campaigns performed aboard the Research Vessel (RV URANIA of the CNR over the Mediterranean sea basin. RGM concentrations have been modelled using a photochemical box model of the MBL and compared to measured data obtained during the research cruises. The comparison results supports the hypothesis that there are daytime mercury oxidation reactions occurring which have not yet been identified. Major findings of key studies carried out during ten years of ship-borne activities have been highlighted.

  19. Generation IV Nuclear Energy Systems Ten-Year Program Plan Fiscal Year 2005, Volume 1

    International Nuclear Information System (INIS)

    None

    2005-01-01

    As reflected in the U.S. ''National Energy Policy'', nuclear energy has a strong role to play in satisfying our nation's future energy security and environmental quality needs. The desirable environmental, economic, and sustainability attributes of nuclear energy give it a cornerstone position, not only in the U.S. energy portfolio, but also in the world's future energy portfolio. Accordingly, on September 20, 2002, U.S. Energy Secretary Spencer Abraham announced that, ''The United States and nine other countries have agreed to develop six Generation IV nuclear energy concepts''. The Secretary also noted that the systems are expected to ''represent significant advances in economics, safety, reliability, proliferation resistance, and waste minimization''. The six systems and their broad, worldwide research and development (R and D) needs are described in ''A Technology Roadmap for Generation IV Nuclear Energy Systems'' (hereafter referred to as the Generation IV Roadmap). The first 10 years of required U.S. R and D contributions to achieve the goals described in the Generation IV Roadmap are outlined in this Program Plan

  20. Generation IV Nuclear Energy Systems Ten-Year Program Plan Fiscal Year 2005, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    None

    2005-03-01

    As reflected in the U.S. ''National Energy Policy'', nuclear energy has a strong role to play in satisfying our nation's future energy security and environmental quality needs. The desirable environmental, economic, and sustainability attributes of nuclear energy give it a cornerstone position, not only in the U.S. energy portfolio, but also in the world's future energy portfolio. Accordingly, on September 20, 2002, U.S. Energy Secretary Spencer Abraham announced that, ''The United States and nine other countries have agreed to develop six Generation IV nuclear energy concepts''. The Secretary also noted that the systems are expected to ''represent significant advances in economics, safety, reliability, proliferation resistance, and waste minimization''. The six systems and their broad, worldwide research and development (R&D) needs are described in ''A Technology Roadmap for Generation IV Nuclear Energy Systems'' (hereafter referred to as the Generation IV Roadmap). The first 10 years of required U.S. R&D contributions to achieve the goals described in the Generation IV Roadmap are outlined in this Program Plan.

  1. Early detection, early symptom progression and symptomatic remission after ten years in a first episode of psychosis study

    DEFF Research Database (Denmark)

    Ten Velden Hegelstad, Wenche; Haahr, Ulrik; Larsen, Tor K

    2013-01-01

    Poor symptom outcome remains a challenge in psychosis: At least 50% of first-episode patients continue to have positive and/or negative symptoms after ten years.......Poor symptom outcome remains a challenge in psychosis: At least 50% of first-episode patients continue to have positive and/or negative symptoms after ten years....

  2. The Talar Body Prosthesis: Results at Ten to Thirty-six Years of Follow-up.

    Science.gov (United States)

    Harnroongroj, Thos; Harnroongroj, Thossart

    2014-07-16

    Satisfactory results of implantation of the talar body prosthesis were reported in 1997, although some complications associated with the initial design were noted. The present study evaluated outcomes of treatment with a modified talar body prosthesis. Of the thirty-six talar body prostheses implanted with use of a transmalleolar surgical approach from 1974 to 2011, thirty-three were available for follow-up at ten to thirty-six years or had failed prior to that time. The indication for implantation had been osteonecrosis in twenty-three patients, a comminuted talar fracture in eight, and a talar body tumor in two. Twenty-eight of the thirty-three prostheses were still in place at the time of final follow-up and five had failed prior to five years. The duration of follow-up was ten to twenty years in eight patients, twenty to thirty years in eleven, and thirty to thirty-six years in nine. The AOFAS (American Orthopaedic Foot & Ankle Society) ankle-hindfoot score did not differ significantly among these three groups. Patients over sixty-five years of age with underlying disease that impeded walking ability had lower AOFAS scores. Early prosthesis failure occurred as a result of size mismatch in two patients, tumor recurrence in one, infection in one, and osteonecrosis of the talar head and neck in one. These failures, which occurred at eight to fifty-seven months, were treated with tibiotalar arthrodesis in three patients, prosthesis revision in one, and below-the-knee amputation in one. Although early prosthesis failure may occur, survival of the talar body prosthesis can provide satisfactory ankle and foot function. Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence. Copyright © 2014 by The Journal of Bone and Joint Surgery, Incorporated.

  3. Exercise-induced bronchospasm and atopy in Ghana: two surveys ten years apart.

    Directory of Open Access Journals (Sweden)

    Emmanuel O D Addo-Yobo

    2007-02-01

    Full Text Available Asthma and allergic diseases have increased in the developed countries. It is important to determine whether the same trends are occurring in the developing countries in Africa. We aimed to determine the time trend in the prevalence of exercise-induced bronchospasm (EIB and atopic sensitisation over a ten-year period in Ghanaian schoolchildren.Two surveys conducted using the same methodology ten years apart (1993 and 2003 among schoolchildren aged 9-16 years attending urban rich (UR, urban poor (UP, and rural (R schools. Exercise provocation consisted of free running for six minutes. Children were skin tested to mite, cat, and dog allergen. 1,095 children were exercised in 1993 and 1,848 in 2003; 916 were skin tested in 1993 and 1,861 in 2003. The prevalence of EIB increased from 3.1% (95% CI 2.2%-4.3% to 5.2% (4.3%-6.3%; absolute percentage increase 2.1% (95% CI 0.6%-3.5%, p < 0.01; among UR, UP, and R children EIB had approximately doubled from 4.2%, 1.4%, and 2.2% to 8.3%, 3.0% and 3.9% respectively. The prevalence of sensitisation had also doubled from 10.6%, 4.7%, and 4.4% to 20.2%, 10.3%, and 9.9% (UR, UP, and R respectively. Mite sensitisation remained unchanged (5.6% versus 6.4%, but sensitisation to cat and dog increased considerably from 0.7% and 0.3% to 4.6% and 3.1%, respectively. In the multiple logistic regression analysis, sensitisation (odds ratio [OR] 1.77, 95% CI 1.12-2.81, age (OR 0.88, 95% CI 0.79-0.98, school (the risk being was significantly lower in UP and R schools: OR 0.40, 95% CI 0.23-0.68 and OR 0.54, 95% CI 0.34-0.86, respectively and year of the study (OR 1.73, 95% CI 1.13-2.66 remained significant and independent associates of EIB.The prevalence of both EIB and sensitisation has approximately doubled over the ten-year period amongst 9- to 16-year-old Ghanaian children irrespective of location, with both EIB and atopy being more common among the UR than the UP and R children.

  4. Idaho National Laboratory 2015-2023 Ten-Year Site Plan

    Energy Technology Data Exchange (ETDEWEB)

    Sheryl Morton; Elizabeth Connell; Bill Buyers; John Reisenauer; Rob Logan; Chris Ischay; Ernest Fossum; Paul Contreras; Joel Zarret; Steve Hill; Jon Tillo

    2013-09-01

    This Idaho National Laboratory (INL) Ten-Year Site Plan (TYSP) describes the strategy for accomplishing the long-term objective of sustaining the INL infrastructure to meet the Department of Energy Office of Nuclear Energy (DOE-NE) mission: to promote nuclear power as a resource capable of making major contributions in meeting the nation’s energy supply, environmental and energy security needs. This TYSP provides the strategy for INL to accomplish its mission by: (1) linking R&D mission goals to core capabilities and infrastructure requirements; (2) establishing a ten-year end-state vision for INL facility complexes; (3) identifying and prioritizing infrastructure needs and capability gaps; (4) establishing maintenance and repair strategies that allow for sustainment of mission-critical (MC) facilities; and (5) applying sustainability principles to each decision and action. The TYSP serves as the infrastructure-planning baseline for INL; and, though budget formulation documents are informed by the TYSP, it is not itself a budget document.

  5. Ten years of telerehabilitation: A literature overview of technologies and clinical applications.

    Science.gov (United States)

    Rogante, Marco; Grigioni, Mauro; Cordella, Daniele; Giacomozzi, Claudia

    2010-01-01

    This paper aims at delivering a structured overview of telerehabilitation literature by analysing the entire set of articles under the search terms "telerehabilitation" or "tele-rehabilitation" to portray "state of the art" ten years after the publication of the first scientific article on the topic. A structured study has been conducted by considering all those articles containing the word "telerehabilitation" or "tele-rehabilitation". Medline, Embase, Cochrane, UK Centre for Reviews and Dissemination, Canadian Agency for Drugs and Technologies in Health databases have been interrogated for articles between 1998 and 2008. 146 scientific articles were found. 56 articles focus on patient treatment, 23 are reviews, 3 are to be considered as both patient treatment papers and reviews, 53 are either technical reports, system descriptions or analyses of new approaches; 8 are general discussion on telerehabilitation. The present paper draw the scenario of the first ten years of telerehabilitation, focussing on clinical applications and technologies. Basically, it confirms the lack of comprehensive studies providing evidence for supporting decision and policy-makers in adopting telerehabilitation technologies in the clinical practice. An overall lack of standardisation in the used terminology also results from the analysis of keywords, which is typical of quite recent fields of application.

  6. First decade: TVA's first ten years of nuclear power plant design and construction experience

    International Nuclear Information System (INIS)

    Willis, W.F.

    1978-01-01

    This paper reviews the experience of the Tennessee Valley Authority's design and construction program for nuclear power plants in terms of schedule and capital costs in three separate phases. Phase one recapitulates the status of the nuclear power industry in 1966 and sets forth the assumptions used for estimating capital costs and projecting schedules for the first Tennessee Valley Authority units. Phase two describes what happened to the program in the hectic early 1970s in terms of expansion of scope (particularly for safety features), the dramatic increase in regulatory requirements, vendor problems, stretchout of project schedules, and unprecented inflation. Phase three addresses the assumptions used today in estimating schedules and plant costs for the next 10-year period. 7 figures, 7 tables

  7. Analyzing the Study of Using Acupuncture in Delivery in the Past Ten Years in China

    Directory of Open Access Journals (Sweden)

    Yingru Chen

    2014-01-01

    Full Text Available The use of acupuncture in inducing delivery has a long history in China. With progress over time, it has been applied in many aspects. For further study of acupuncture in delivery, this paper analyzed the papers using acupuncture in delivery in the past ten years in mainland China. 87 literatures were picked out by searching relevant electronic databases and bibliographies of relevant journals. The analysis showed randomized controlled trials that were the major type of research, while preclinical researches and literature reviews only account for around ten percent, respectively. Clinical researches indicated that acupuncture can relieve labor pain, promote maternal uterine contraction, shorten birth process, and treat postpartum disorders. Preclinical researches found that acupuncture can adjust certain hormones and improve uterus contraction of late-stage pregnant rats. However, due to lack of large multicenter randomized controlled clinical trials, standardized evaluations of clinical effects in clinical researches and detailed mechanism study in preclinical researches and unequivocal conclusions about the effectiveness, efficacy, and mechanisms of acupuncture in this field cannot be obtained from those researches yet. Further clinical and preclinical studies about the use of acupuncture in delivery with improved methodology is still needed.

  8. Ten Years, Twenty Issues, and Two Hundred Papers of Numeracy: Toward International Reach and Transdisciplinary Utility

    Directory of Open Access Journals (Sweden)

    H.L. Vacher

    2017-07-01

    Full Text Available This issue completes the first ten years of Numeracy. The purpose of this introductory editorial is to review what has happened to the journal in those ten years. In the twenty issues, Numeracy’s output has been 201 papers counting the one or two editorials per issue. More than 50% of the papers are full, peer-reviewed articles, including 13 papers in two theme collections. The others are peer-reviewed notes and perspectives, editor-reviewed book reviews (15% of the total, and a column by contributing co-editor, Dorothy Wallace. The current issue marks an upswing in the number of notes, and our first discussion/reply. The number of papers per year has been increasing (e.g., 66% more in the last three years than in the first three years. The download rate has increased from about 5,000 in the first two years to 5,000 in about 40 days now. The editorial goes on to document two main outcomes. First, the journal is gaining an international reach: more than half the downloads occur outside the United States now, and the number of contributions from outside the United States has increased from 4 in the first five years to 15 in the second five years. Second, the across-the-curriculum nature of quantitative literacy is coming to the fore. The transdisciplinarity of QL is strikingly evident in this issue, which is discussed in some detail, especially how it conforms to the mission of the Association of American Colleges and Universities. The editorial ends with some results from a small ad hoc study of Google Scholar Citation Profiles. The question was, of the profiles that used “numeracy” or “quantitative literacy” as keywords, what other keywords did those profiles use, and what were the source countries? The results show that (1 QL is very much an American term, (2 there is, metaphorically, a vast and interesting numeracy ecosystem out there for Numeracy to engage and serve, and (3 as we become more global, the transdisciplinary relevance

  9. [Chest wall and vertebral en-bloc resection for sarcoma: ten-year experience].

    Science.gov (United States)

    Incarbone, M; Alloisio, M; Luzzati, S; Testori, A; Cariboni, U; Infante, M; Errico, V; Canevini, M; Ravasi, G

    2005-08-01

    We reviewed our ten-year experience with surgical en-bloc chest wall and vertebral resection for sarcoma invading the spine, and verified five-year survival and feasibility of this aggressive surgery. From 1994 to 1999, 13 patients underwent surgical en-bloc resection for primary sarcoma of the chest wall involving the spine. Concurrent pulmonary resection was performed in 12 cases. A single hemi-vertebrectomy was performed in 2 patients, a triple hemi-vertebrectomy in 2, a complete vertebrectomy in 4, a triple complete vertebrectomy in 5. Significative morbidity occurred in 1 patient who had lower limbs paralysis (9%). Perioperative mortality occurred in 2 patients (15.4%): 1 operative death for bleeding and 1 patients for a adult respiratory distress syndrome (ARDS). The overall five-year survival was 30.8%, excluding the 2 perioperative deaths the five-year survival resulted 36.4%. In spite of the limited number of patients, the morbidity and mortality outcome and the five-year survival leads us to think that surgery is the main therapy for primary chest wall sarcomas involving the spine. En-bloc chest wall and vertebral resection is a safe and effective treatment.

  10. Primary Progressive Orofacial Apraxia: A Ten-Year Long Follow-Up Case Report.

    Science.gov (United States)

    Trebbastoni, Alessandro; D'Antonio, Fabrizia; de Lena, Carlo; Onesti, Emanuela; John, Bev; Inghilleri, Maurizio

    2016-10-04

    Orofacial apraxia (OA) as the main symptom in neurodegenerative disorders has not been yet reported. We present the case of a woman with a 22-month long history of isolated OA, studied with cerebrospinal fluid biomarkers and repeated clinical, neuropsychological, and morpho-functional evaluations. Baseline morpho-functional neuroimages revealed a left frontal operculum hypoperfusion with a widespread fronto-temporal involvement at follow-up. Cerebrospinal fluid concentrations of tau and amyloid-β were normal. The ten-year long clinical observation disclosed progressive OA worsening and the late onset of frontal functions impairment and extrapyramidal signs. The early and late stages of a neurodegenerative syndrome with OA as the main clinical feature were characterized.

  11. The State of the Art Ten Years After a State of the Art

    DEFF Research Database (Denmark)

    Sturm, Bob L.

    2014-01-01

    A decade has passed since the first review of research on a ``flagship application" of music information retrieval (MIR): the problem of music genre recognition (MGR). During this time, about 500 works addressing MGR have been published, and at least 10 campaigns have been run to evaluate MGR...... published research using the most-used benchmark dataset in MGR during the past decade: {\\em GTZAN}. We show that none of the evaluations in these many works is valid to produce conclusions with respect to {\\em recognizing genre}, i.e., that a system is using criteria relevant to recognize genre. In fact......, the problems of validity in evaluation also affect research in music emotion recognition and autotagging. We conclude by discussing the implications of our work for MGR and MIR in the next ten years....

  12. The church and society in South Africa celebrating first ten years of democracy (1994-2004

    Directory of Open Access Journals (Sweden)

    R T H Dolamo

    2005-10-01

    Full Text Available In this article, colonialism, slavery, racism and apartheid are singled out as scourges that have afflicted South Africans for over three-and-half centuries in respect of the first four scourge, and for four-and-half decades in respect of apartheid.� Against this backdrop, the struggles of the people of South Africa against these scourges are portrayed and analysed.� With the attainment of freedom and democracy in 1994, the� ANC led government enacted pieces of legislation whose aim was to deepen and broaden democracy, thereby transforming the society beyond recognition of how it was before 1994. Celebrating the first ten years of freedom and democracy, the people of South Africa are taking stock of what has been achieved and not achieved and bracing themselves for the challenges that are facing them into the second decade.

  13. Response of the desert shrub Krameria parvifolia after ten years of chronic gamma irradiation

    International Nuclear Information System (INIS)

    Vollmer, A.T.; Bamberg, S.A.

    1975-01-01

    A northern Mojave Desert shrub community was irradiated by a 137 Cs source for a ten-year period. Leaf and fruit production, cover, and percent live stem of Krameria parvifolia shrubs were found to respond significantly to a radiation gradient with exposure rates ranging from 0.1 to 10 R/day. Fruit and leaf production were greatly reduced at exposures over 6 R/day. Above 7 R/day 16% of the shrubs were dead compared to 1.2% in a non-irradiated area. Reduced cover, density and live stem values indicate a trend toward a lower status of Krameria in the community at cumulative exposures above 25 kR. Observations indicate that an equilibrium in response to irradiation has not yet occurred. Radiosensitivity of K. parvifolia is attributed in part to its phenology. (author)

  14. [Analysis of body mass index in different sector workers for over ten years].

    Science.gov (United States)

    Perbellini, L; Zonzin, C; Baldo, M

    2010-01-01

    A critical review of the literature on obesity and overweight underlines that a low educational level, a low social-economic status, certain working conditions, the lack of physical activity in leisure time, together with the availability of food, are the main factors favouring increased prevalence of obesity. Certain jobs also contribute significantly to this problem. Automation, the use of machines for heavy works and sedentary activities favour body weight increase. Jobs that are a source of stress, such as work with night shift can cause metabolic disorders leading to an increased prevalence of obesity. The main aim of this article is to study the trend of body weight in different working area during ten years, comparing this parameter to different factors such as job, blood pressure, smoke, alcool and health diseases.

  15. A ten-year search for synchronous cells: obstacles, solutions and practical applications

    Directory of Open Access Journals (Sweden)

    Charles Edward Helmstetter

    2015-03-01

    Full Text Available My effort to use synchronously dividing cultures to examine the Escherichia coli cell cycle involved a ten-year struggle with failure after failure punctuated by a few gratifying successes, especially at the end. In this essay, I recount my personal journey in this obsessive experimental pursuit. That narrative is followed by a description of a simplified version of the baby machine, a technique that was developed to obtain minimally disturbed, synchronously growing E. coli cells. Subsequent studies with this methodology led to an understanding of the basic properties of the relationship between chromosome replication and cell division. Accordingly, I end this reminiscence with a simple, fool-proof graphical strategy for deducing the pattern of chromosome replication during the division cycle of cells growing at any rate.

  16. Idaho National Laboratory Ten-Year Site Plan Project Description Document

    Energy Technology Data Exchange (ETDEWEB)

    Not Listed

    2012-03-01

    This document describes the currently active and proposed infrastructure projects listed in Appendix B of the Idaho National Laboratory 2013-2022 Ten Year Site Plan (DOE/ID-11449). It was produced in accordance with Contract Data Requirements List I.06. The projects delineated in this document support infrastructure needs at INL's Research and Education Campus, Materials and Fuels Complex, Advanced Test Reactor Complex and the greater site-wide area. The projects provide critical infrastructure needed to meet current and future INL opereational and research needs. Execution of these projects will restore, rebuild, and revitalize INL's physical infrastructure; enhance program execution, and make a significant contribution toward reducing complex-wide deferred maintenance.

  17. Ten Year Development Plan for the GRTgaz Network 2012-2021

    International Nuclear Information System (INIS)

    2012-09-01

    GRTgaz is a European leader in natural gas transmission, a world expert in gas transmission networks and systems, and an operator firmly committed to the energy transition. It owns and operates the gas transmission network throughout most of France and it manages the transmission network in Germany, thereby helping to ensure correct operation of the French and European gas market. It contributes to the energy security of regional supply systems and performs a public service mission to ensure the continuity of consumer supply. In accordance with the French Energy Code, GRTgaz publishes a 10-year development plan for its gas distribution network in France every year. This document is produced in line with European and French energy policies. It identifies the transport infrastructure that will need to be built over the next three years, and presents the main infrastructure that is likely to be developed within the next ten years. It incorporates the supply security obligations that TSOs are required to fulfil. It takes account of interested parties' needs and projects at the national, supranational and European levels. It is based on existing gas supply and demand and reasonable medium-term development forecasts for gas infrastructure, consumption and international trade

  18. [Ten years of human papilloma virus vaccination. From dermatology to oncology via the infectious diseases department].

    Science.gov (United States)

    Moraga-Llop, Fernando A

    2018-02-07

    Human papilloma virus (HPV) was first identified in dermatology, and it was subsequently demonstrated that is was required for the development of uterine cervical cancer and other tumours, after a persistent infection by any of its oncogenic genotypes. Ten years ago, the most common infections and cancers associated with HPV could be prevented by immunisation with 2vaccines, one bivalent, and another tetravalent, and having just marketed a nonavalent one. During the period 2007-2008, the HPV vaccine was included in the Autonomous Communities vaccination calendar, and it is the second vaccine, after that of Hepatitis B, that prevents cancer. In these 10 years that these vaccines have been available the knowledge has progressed and there have been significant advances in vaccination strategies, as well as in the indications and recommendations. These include, lowering the age in the vaccination schedule, prescribing of 2doses at 9 years and at 13-14 years, systematic vaccination of the male in some countries, immunisation of the woman after adolescence, implementation of vaccination programmes in developed countries, prevention of other cancers, recommendations for vaccinations for populations at high risk of HPV infection, scientific evidence on the impact and effectiveness of vaccination, and confirmation of the safety of these vaccines, with more than 270 million doses administered, as has already been observed in clinical trials. The role of health professionals is essential to achieve and maintain high vaccine coverage. Copyright © 2018. Publicado por Elsevier España, S.L.U.

  19. Ten-year development plan for the GRTgaz transmission network 2015-2024 period

    International Nuclear Information System (INIS)

    2015-11-01

    GRTgaz is a European leader in natural gas transmission, a world expert in gas transmission networks and systems, and an operator firmly committed to the energy transition. It owns and operates the gas transmission network throughout most of France and it manages the transmission network in Germany, thereby helping to ensure correct operation of the French and European gas market. It contributes to the energy security of regional supply systems and performs a public service mission to ensure the continuity of consumer supply. In accordance with the French Energy Code, GRTgaz publishes a 10-year development plan for its gas distribution network in France every year. This document is produced in line with European and French energy policies. It identifies the transport infrastructure that will need to be built over the next three years, and presents the main infrastructure that is likely to be developed within the next ten years. It incorporates the supply security obligations that TSOs are required to fulfil. It takes account of interested parties' needs and projects at the national, supranational and European levels. It is based on existing gas supply and demand and reasonable medium-term development forecasts for gas infrastructure, consumption and international trade

  20. Green Tea as an Agricultural Based Health Promoting Food: The Past Five to Ten Years

    Directory of Open Access Journals (Sweden)

    Qin-Yin Shi

    2012-12-01

    Full Text Available The consumption of tea originated in ancient China over 4000 years ago and is currently the second most popular beverage in the world after water. Tea is an aromatic beverage prepared by pouring hot water over cured leaves of the Camellia sinensis plant. The link between tea intake, most notably green tea, and health has resulted in intense research on the components responsible for preventing the onset of several chronic diseases, including atherosclerosis, cancer, obesity and diabetes. In particular, the high levels of chemically diverse phenols (e.g., phenolic acids, flavonoids present in tea exhibit potent protective properties against many of these diseases. Although health related research on green tea and its predominant phenol (catechins has been on-going for decades, major advances have occurred in the last 5–10 years. Therefore, this review focuses on seminal studies reported primarily within the last five years but not extending past ten years on the link between health and green tea with an emphasis on the catechins.

  1. Lunar radionuclide records of average solar-cosmic-ray fluxes over the last ten million years

    International Nuclear Information System (INIS)

    Reedy, R.C.

    1980-01-01

    Because changes in solar activity can modify the fluxes of cosmic-ray particles in the solar system, the nature of the galactic and solar cosmic rays and their interactions with matter are described and used to study the ancient sun. The use of cosmogenic nuclides in meteorites and lunar samples as detectors of past cosmic-ray variations are discussed. Meteorite records of the history of the galactic cosmic rays are reviewed. The fluxes of solar protons over various time periods as determined from lunar radionuclide data are presented and examined. The intensities of solar protons emitted during 1954 to 1964 (11-year solar cycle number 19) were much larger than those for 1965 to 1975 (solar cycle 20). Average solar-proton fluxes determined for the last one to ten million years from lunar 26 Al and 53 Mn data show little variation and are similar to the fluxes for recent solar cycles. Lunar activities of 14 C (and preliminary results for 81 Kr) indicate that the average fluxes of solar protons over the last 10 4 (and 10 5 ) years are several times larger than those for the last 10 6 to 10 7 years; however, cross-section measurements and other work are needed to confirm these flux variations

  2. Ten-year development plan for the GRTgaz transmission network 2016-2025 period

    International Nuclear Information System (INIS)

    2016-11-01

    GRTgaz is a European leader in natural gas transmission, a world expert in gas transmission networks and systems, and an operator firmly committed to the energy transition. It owns and operates the gas transmission network throughout most of France and it manages the transmission network in Germany, thereby helping to ensure correct operation of the French and European gas market. It contributes to the energy security of regional supply systems and performs a public service mission to ensure the continuity of consumer supply. In accordance with the French Energy Code, GRTgaz publishes a 10-year development plan for its gas distribution network in France every year. This document is produced in line with European and French energy policies. It identifies the transport infrastructure that will need to be built over the next three years, and presents the main infrastructure that is likely to be developed within the next ten years. It incorporates the supply security obligations that TSOs are required to fulfil. It takes account of interested parties' needs and projects at the national, supranational and European levels. It is based on existing gas supply and demand and reasonable medium-term development forecasts for gas infrastructure, consumption and international trade

  3. A Ten Year Analysis of Fatal Peripheral Vascular Injuries Autopsy Study

    Directory of Open Access Journals (Sweden)

    Salim Tuncer

    2016-04-01

    Full Text Available Aim: Peripheral vascular injuries are usually associated with fatal injuries. Early diagnosis and intervention are so vital for improving a favorable outcome for traumatic vascular injuries. As a preventable cause of death, we aimed to evaluate peripheral vascular injuries in overall deaths in ten year period, 2003-2012. Material and Method: A retrospective evaluation was made of 2845 death cases which had post-mortem examination and autopsy from the 10-year period of 2003-2012 in Eskisehir, Turkey. The mean age of the cases included in the study was 32.5±7.9 years with the highest rate of cases occurring in the 30-39 years age group. Males constituted 89.2% of the victims. The most frequent manner of death was homicide 83.8%.The femoral artery was the most commonly injured vessel 29 cases (78.4%. In this study it was identified that, 33 patients (89.3% died before any medical intervention could be performed. Discussion: Our study shows that, peripheral vascular injuries most commonly caused by sharp objects. The injuries have a low mortality rate when early intervention is made. Autopsies are conducted is very important to explain not only the cause of death but also the treatment process, which would clear the cases of any potential malpractice or negligence claims.

  4. Ten-Year Development Plan for the GRTgaz Transmission Network 2011-2020 Period

    International Nuclear Information System (INIS)

    2011-10-01

    GRTgaz is a European leader in natural gas transmission, a world expert in gas transmission networks and systems, and an operator firmly committed to the energy transition. It owns and operates the gas transmission network throughout most of France and it manages the transmission network in Germany, thereby helping to ensure correct operation of the French and European gas market. It contributes to the energy security of regional supply systems and performs a public service mission to ensure the continuity of consumer supply. In accordance with the French Energy Code, GRTgaz publishes a 10-year development plan for its gas distribution network in France every year. This document is produced in line with European and French energy policies. It identifies the transport infrastructure that will need to be built over the next three years, and presents the main infrastructure that is likely to be developed within the next ten years. It incorporates the supply security obligations that TSOs are required to fulfil. It takes account of interested parties' needs and projects at the national, supranational and European levels. It is based on existing gas supply and demand and reasonable medium-term development forecasts for gas infrastructure, consumption and international trade

  5. Deep Vadose Zone Characterization at the Hanford Site: Accomplishments from the Last Ten Years

    International Nuclear Information System (INIS)

    Brown, Christopher F.; Serne, R. Jeffrey

    2008-01-01

    The overall goal of the Tank Farm Vadose Zone Project, led by CH2M HILL Hanford Group, Inc., is to define risks from past and future single-shell tank farm activities at Hanford. To meet this goal, CH2M HILL Hanford Group, Inc. tasked scientists from Pacific Northwest National Laboratory (PNNL) to perform detailed analyses on vadose zone sediments collected within/adjacent to the twelve single-shell tank farms contained within Hanford's Central Plateau region. This work has been performed under the Resource Conservation and Recovery Act (RCRA) Corrective Action Program and is associated with the Hanford Federal Facility Agreement and Consent Order. While there are many facets to the laboratory studies employed by PNNL, the four primary objectives of this work are to: identify the type and quantity of contamination present, understand the physical processes that affect the transport of contaminants in the vadose zone sediments, when practical, identify the source(s) of the contamination found in the sediment samples, and when practical, determine if a link can be made between the vadose zone contamination observed and any known groundwater contaminants in the vicinity. Since its inception in 1997, PNNL's Vadose Zone Characterization Project has evolved to better meet these four key objectives. The single-largest adaptation of the Vadose Zone Characterization Project over its ten years of operation was the advent of a tiered sample analysis approach. Use of a tiered approach allows resources to be focused on those samples/tests that provide the largest amount of scientific information to best meet the four key project objectives within the budget available. Another significant, but more recent, adaptation has been the implementation of a rapid turnaround characterization process in which sediment samples are analyzed in near real-time to aid drilling activities within the tank farms. This paper highlights details of the characterization activities performed as well

  6. Medical School Attrition-Beyond the Statistics A Ten Year Retrospective Study

    Directory of Open Access Journals (Sweden)

    Maher Bridget M

    2013-01-01

    Full Text Available Abstract Background Medical school attrition is important - securing a place in medical school is difficult and a high attrition rate can affect the academic reputation of a medical school and staff morale. More important, however, are the personal consequences of dropout for the student. The aims of our study were to examine factors associated with attrition over a ten-year period (2001–2011 and to study the personal effects of dropout on individual students. Methods The study included quantitative analysis of completed cohorts and qualitative analysis of ten-year data. Data were collected from individual student files, examination and admission records, exit interviews and staff interviews. Statistical analysis was carried out on five successive completed cohorts. Qualitative data from student files was transcribed and independently analysed by three authors. Data was coded and categorized and key themes were identified. Results Overall attrition rate was 5.7% (45/779 in 6 completed cohorts when students who transferred to other medical courses were excluded. Students from Kuwait and United Arab Emirates had the highest dropout rate (RR = 5.70, 95% Confidence Intervals 2.65 to 12.27;p  Absenteeism was documented in 30% of students, academic difficulty in 55.7%, social isolation in 20%, and psychological morbidity in 40% (higher than other studies. Qualitative analysis revealed recurrent themes of isolation, failure, and despair. Student Welfare services were only accessed by one-third of dropout students. Conclusions While dropout is often multifactorial, certain red flag signals may alert us to risk of dropout including non-EU origin, academic struggling, absenteeism, social isolation, depression and leave of absence. Psychological morbidity amongst dropout students is high and Student Welfare services should be actively promoted. Absenteeism should prompt early intervention. Behind every dropout statistic lies a personal story. All

  7. Prognostic factors in children with acute lymphoblastic leukemia: a ten year study

    Directory of Open Access Journals (Sweden)

    Oloomi yazdi Z.

    2008-06-01

    Full Text Available Background: Acute lymphoblastic leukemia (ALL is the most common cancer in the pediatric population. With modern treatments, the chance of the complete recovery is nearly 100%. The most important prognostic factors are appropriate treatment protocol and determination of patient risk factors based on clinical, morphological, immunological and cytological characteristics. In this study we reviewed frequency of these factors, like as age, gender, the primary white blood cell number, sub- group on the base of FAB classification, immunophenotype and the clinical progress. Methods: In this retrospective study, we reviewed 877 pediatric patients with the diagnosis of ALL between the years of 1994 and 2004. In these patients the age, gender, primary WBC count, sub-group based on the FAB classification, immunophenotype and the clinical progress in 177 patient with acute lymphoblastic leukemia at Imam Khomeini Hospital between the years of 1994 to 2004 were determined. Results: Of these patients, 1.6% was younger than one year, 24.8% more than ten years old and 73.6% were between the ages of one and ten years; 63.8% were male. WBC counts were above 50,000/ul in 28.8% of the patients. FAB classifications included L1 in 80.2%, L2 in 17.5% and L3 in 2.3% of the patients. Immunophenotypes included pre-B cell in 63.8%, early pre-B cell in 23.1%, T cell in 12.3% and mature B cell in 0.8% of the patients. Marker CD10+ was detected in 88.1% of the B cell cases. In this study group, 74% of the patients recovered, 16.3% died and 16.5% relapsed.Conclusions: The prevalence of FAB-L1 and pre-B cell cases in this study is greater than a previous study, while the prevalence of FAB-L2 and early pre-B cell cases is less than that of the previous study.

  8. Management of orbital cellulitis and subperiosteal orbital abscess in pediatric patients: A ten-year review.

    Science.gov (United States)

    Sciarretta, Vittorio; Demattè, Marco; Farneti, Paolo; Fornaciari, Martina; Corsini, Ilaria; Piccin, Ottavio; Saggese, Domenico; Fernandez, Ignacio Javier

    2017-05-01

    Pediatric periorbital cellulitis represents a common disease complicating a nasal infection. A ten-year retrospective review of fifty-seven children admitted to our institution with the diagnosis of periorbital cellulitis as a complication of sinus infections was carried out. The age varied from one month to eleven years (mean 3.9 years). Thirty-five were males (62%), while twenty-two were females (38%). Nine out of fifty-seven (15.8%) presented exophthalmos associated with eyelid erythema and edema, while the rest suffered mainly from eyelid erythema and edema. Twenty-two patients complaining of exophthalmos or not responding to medical therapy within 48 h were assessed with a computed tomography scan (38.6%). A subperiosteal orbital abscess was detected in nine cases and these patients underwent surgical drainage (15,8%). Recurrence of orbital infection occurred in three cases (5.3%). Medical management is the main treatment for both preseptal and postseptal orbital cellulitis. Nevertheless, there is no universally accepted guideline for the treatment of subperiosteal abscesses and each case should be treated accordingly. Urgent surgical drainage should be considered in cases not responding to adequate medical management, or those cases presenting visual deterioration. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Who will be using oil-fired furnaces in ten years time?

    International Nuclear Information System (INIS)

    1992-05-01

    Danish total oil consumption amounted to 355 PJ per year during 1990. Compared with 1976, this indicates a reduction of ca. 50%. At the same time domestic resources, from the North Sea, are supplanting import. Danish energy policy aims at a further reduction of oil consumption, aimed at the goal of 285 PJ annually by the year 2005. Of this amount, only 40% should be used for heating used in the public sectors, electricity production and industrial processes. Of residential buildings constructed in 1991, merely 5% were installed with oil-burning heaters. The aim was to analyze the current Danish oil market and to determine who uses oil for individual space heating, and how the market will develop in the future. To this purpose the types of buildings in Denmark which are now heated with the help of individual oil-burning boilers (580,000 units, covering 2 mio. m 3 ) are examined with regard to customer-type, size and age of buildings and conditions of ownership. The section of the market for each customer type is designated. The customers' geographical location with regard to competitive supply possibilities (i.e. district heating and natural gas) is dealt with in addition to the division of the market into rural, urban and municipal areas. A number of scenarios which illustrate possible developments for the individual oil market during the next ten years are presented. (AB)

  10. Ten-year survival rates of teeth adjacent to treated and untreated posterior bounded edentulous spaces.

    Science.gov (United States)

    Aquilino, S A; Shugars, D A; Bader, J D; White, B A

    2001-05-01

    Failure to replace a single missing posterior tooth may lead to a variety of dental problems, which may ultimately result in tooth loss. However, little is known about the fate of the adjacent teeth if a missing posterior tooth is not replaced. This retrospective study evaluated the survival of teeth adjacent to treated and untreated posterior bounded edentulous spaces. Data were obtained from electronic treatment records from the Kaiser Permanente Dental Care Program, Portland, Ore. A final sample of 317 patients who met the study inclusion criteria was identified. Each bounded edentulous space was placed in 1 of 3 treatment categories: untreated, restored with a fixed partial denture, or restored with a removable partial denture. Subsequent treatment and the status of the teeth adjacent to the bounded edentulous space were followed through December 1999. Ten-year Kaplan-Meier survival estimates were generated for each treatment group, and differences in survival were evaluated with the log-rank chi-square test (alpha=.05). There was a significant difference in survival among the 3 treatment categories (P=.005). Spaces restored with a fixed partial denture had longer 10-year survival estimates (92%) than those that remained untreated (81%). Spaces restored with a removable partial denture had the poorest 10-year survival rate (56%). Under the conditions and selection bias associated with this retrospective study, the survival of teeth adjacent to a single posterior edentulous space was negatively associated with removable partial denture placement compared with no treatment or the use of a fixed partial denture.

  11. [Evidence Based Occupational Medicine: ten year experience with audiometric examination in a handicraft company].

    Science.gov (United States)

    Maccacaro, G; Baratieri, S; Princivalle, A; Perbellini, L

    2007-01-01

    This work describes the audiometry threshold assessment of 1000 workers employed in different artisan categories during a period of ten-year noise professional exposure. The hearing loss noise-induced rates were determined by analysing audiometric tests at the beginning of our period of study and after 5 and 10 years of noise exposure. Environmental noise exposures were on average 88 dB(A), but near 90 dB(A) in some work categories. Workers widely used hearing protection devices, nearly at 93%, during the period we studied. The Evidence Based Occupational Medicine should find out points of reference proving the efficiency and effectiveness of occupational physicians: in this case, a positive trend in the reduction of hearing loss rate will be expected to confirm the goodness of prevention practice. Our study suggests that the levels of protection so far accepted are not effective enough in order to reduce the incidence of noise-induced hearing loss in the course of the years: in despite of most accredited predicting models for hearing conservation programs, a significant percentage of workers exposed to industrial noise continues to present a high incidence of hearing loss. The Evidence Based Occupational Medicine suggests that the proposed prevention activities carried out in the described factories were not enough effective.

  12. Magnetic resonance imaging is not suitable for interpretation of meniscal status ten years after arthroscopic repair.

    Science.gov (United States)

    Pujol, Nicolas; Tardy, Nicolas; Boisrenoult, Philippe; Beaufils, Philippe

    2013-12-01

    The purpose of this study was to assess the MRI features of the all-inside repaired meniscus in the long-term. Among 27 consecutive all-inside arthroscopic meniscal repairs, 23 patients aged 25 ± 5 years at the time of surgery were reviewed at a median follow-up of 10 ± 1 years. Retrospective clinical examinations and imaging assessments using a 1.5-T MRI after all-inside arthroscopic meniscal repair were conducted. At follow-up, Lysholm and IKDC averaged 89 ± 11 and 95 ± 8, respectively. MRI examinations revealed no meniscal signal alteration in three patients (13%), a vertical signal located in the previously torn area in seven (30%), a horizontal grade 3 in nine (39%), and a complex tear (grade 4) in four (17.5%). There were no differences between medial and lateral menisci (p = 0.15), stable and stabilised knees (p = 0.56). Several abnormal vertical and/or horizontal hypersignals are still present on MRI examination ten years after arthroscopic all-inside meniscal repair. The appearance of early signs of osteoarthritis is rare, suggesting a chondroprotective effect of the repaired meniscus.

  13. Survivorship and clinical outcome of Birmingham hip resurfacing: a minimum ten years' follow-up.

    Science.gov (United States)

    Azam, Md Quamar; McMahon, Stephen; Hawdon, Gabrielle; Sankineani, Sukesh Rao

    2016-01-01

    Resurfacing as a percentage of total hip arthroplasty rose from 5.6 % in 2001 to 8.9 % in 2005 in Australia. During the same period the resurfacing to conventional prosthesis rose from 19.6 % to 29 % in the younger age group (less than 55 years). Long term (more than ten years) functional results of BHR are sparingly documented. Among the literatures available, the patient selection criteria vary from osteoarthritis, avascular necrosis, and dysplastic hip to slipped capital femoral epiphysis. The objective of the current study is to evaluate long term survivorship and functional outcome of Birmingham hip resurfacing surgery in osteoarthritic hip patients performed by a single surgeon. In this retrospective clinical study, all patients who underwent hip resurfacing for osteoarthritis of hip between 1999 and 2004 are included. All surgeries were performed by single surgeon (SJM) and in all patients Smith & Nephew system (Midland Medical Technologies, Birmingham, United Kingdom)) was used. Revision surgery is considered the end point of survivorship. Means, standard deviations, and confidence interval were calculated for all continuous measures. Survival analysis was performed with the Kaplan-Meier method and 95 % confidence intervals were calculated. The result is based on 222 patients (244 hips). This included 153 males and 69 females. Our mean follow up was 12.05 years and overall survival was 93.7 %. In terms of gender, survival in males was 95.43 % while in females it was 89.86 %. Failure was seen in 14 patients (16 hips), which included seven female (10.14 %) and seven male (4.57 %) patients. Failure of femoral components due to aseptic loosening and varus collapse was seen in eight patients after a mean 9.6 years. Metal allergy was seen in three patients (five hips), all of them were female of which two had bilateral resurfacing. Other complications included femoral neck stress fractures in two patients and acetabular component loosening in one patient. We

  14. More than skin deep. Ten year follow-up of delayed cutaneous adverse drug reactions (CADR).

    Science.gov (United States)

    Graudins, Linda Velta; Ly, Jenny; Trubiano, Jason; Aung, Ar Kar

    2016-10-01

    To determine the gaps in practice regarding appropriate ADR documentation and risk communication for patients diagnosed with severe cutaneous adverse drug reactions (CADR). This was a retrospective observational cohort study conducted using hospital coding and databases to identify inpatients diagnosed with CADR from January 2004 to August 2014. Hospital discharge summaries, ADR reports and pharmacy dispensing records were reviewed for ADR documentation. Patients still living in Australia and who did not opt out of being contacted were invited to be surveyed by telephone to determine their understanding of recommendations, re-exposure rates and long-term effects. Of 85 patients identified, median age was 59 (IQR 44-72) years and 47.1% were male. The most common diagnosis was TENS (49.4%). Ten patients (11.8%) died as inpatients. Of the 81 patients with a drug-related causality, 47 (58%) had appropriate documentation in all three required medical record platforms. Of the 56 eligible patients, 38 (67.9%) were surveyed; 13% had no information provided upon discharge and 26.3% patients had a mismatch in knowledge of implicated medications. No surveyed patient had a relapse of CADR, but 23.7% had a subsequent unrelated allergic reaction. Thirteen patients (34.2%) reported long-term effects. We found gaps in the accuracy of ADR documentation and communication of risk at discharge, which indicated risks to patient safety. Electronic systems are being developed to improve documentation. Written information about CADR is being provided at discharge to improve patient understanding and knowledge. © 2016 The British Pharmacological Society.

  15. Identification of irradiated foods. Experiences from the ten years' control in Finland

    International Nuclear Information System (INIS)

    Pinnioja, S.; Jernstroem, J.; Arponen, E.

    2002-01-01

    Complete text of publication follows. The official control of irradiated foods has been performed since the year 1991 in Finland. The national legislation on food irradiation was similar as the new European directive allowing treatment of herbs, spices and seasonings for the purpose of decreasing the microbe content in foods. Irradiation treatment needs to be labelled. The Finnish degree allowed a five weight percent maximum amount of irradiated spice portion when labelling of radiation treatment was not needed. The official control of irradiated foods belongs to the Finnish Food Administration, who has given the practical control responsibility to the Finnish Customs Laboratory. Prescreening of food samples for identification of radiation treatment is performed at the Customs Laboratory. Those samples resulting a positive or moderate signal for irradiation will be sent to the Laboratory of Radiochemistry at the University of Helsinki for the thermoluminescence (TL) analysis. During the five first control years the prescreening was performed based on the total microbe content and the determination of fumigation residues from food samples. Since 1995 prescreening has been performed with a photostimulated luminescence (PSL) instrument. Control of irradiated foods has been applied mostly to herbs, spices and seasonings, and products containing these. Different seafood products, fresh berry, mushroom, herbal products and some animal products have been analysed during the ten years period. The amount of irradiated food imported in Finland is not high. Less than 3% of herbs and spices were found to have been irradiated. During the early years of the control irradiated seafood was found; about 5% of seafood products analysed by the TL analysis were found to have been irradiated. During the past two years only one seafood sample was irradiated. Irradiated berries or mushrooms have not been found so far

  16. Development of a mathematical phantom representing a ten-year-old for use in internal dosimetry calculations

    International Nuclear Information System (INIS)

    Deus, S.F.; Poston, J.W.

    1976-01-01

    A phantom was developed representing a ten-year old child for use as the basis for dosimetric studies. An initial literature survey was made to determine organ mass, shape, and location in a normal ten-year-old child. These data were used to construct a mathematical representation of the child for use in computer calculations of absorbed radiation dose for typical exposure situations following the administration of radiopharmaceuticals

  17. THE LAND-USE AND LAND-COVER CHANGE ANALYSIS IN BEIJING HUAIROU IN LAST TEN YEARS

    Directory of Open Access Journals (Sweden)

    Q. Zhao

    2018-04-01

    Full Text Available With eCognition software, the sample-based object-oriented classification method is used. Remote sensing images in Huairou district of Beijing had been classified using remote sensing images of last ten years. According to the results of image processing, the land use types in Huairou district of Beijing were analyzed in the past ten years, and the changes of land use types in Huairou district were obtained, and the reasons for its occurrence were analyzed.

  18. On Brazil participation in the first ten years of the INPRO Project and perceptivities ahead

    International Nuclear Information System (INIS)

    Goncalves Filho, Orlando Joao Agostinho

    2011-01-01

    In September 2001, the International Atomic Energy Agency (IAEA) launched the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) to help ensure that nuclear energy is available to contribute to meeting the world energy needs of the 21st century in a sustainable manner. To achieve its objective INPRO brings together technology holders and technology users to consider jointly the international and the national actions to achieve the desired innovations in nuclear reactors, fuel cycles and institutional approaches. This paper reviews INPRO's main achievements in its first ten years of existence and highlights Brazil's contributions to the project and the benefits gained from its membership. Among INPRO's main achievements are the development of the INPRO assessment methodology, key studies and collaborative project results, and the establishment of the Dialogue Forum between technology holders and technology users. Brazil contributed to the project by providing a cost-free expert to the INPRO Coordination Group in 2002, by performing an assessment of two small sized reactors for deployment in the country using INPRO methodology published in 2009, and by participating in two collaborative projects related to technology innovations, which shall be completed by the end of this year. The paper concludes with a short presentation of the opportunities for the country's participation in the activities of the INPRO Action Plan for the biennium 2012-2013, currently under preparation. (author)

  19. Case report on xeroderma pigmentosum with squamous cell carcinoma in a ten year old child

    Directory of Open Access Journals (Sweden)

    Uday Kumar Sonnappa

    2018-04-01

    Full Text Available Xeroderma pigmentosum (XPis a rare inherited skin disorder characterized by a heightened sensitivity to the DNA damaging effects of ultraviolet radiation (UV. The main source of UV is the sun. The symptoms of XP can be seen in any sun-exposed area of the body. The effects are greatest on the skin, the eyelids and the surface of the eyes but the tip of the tongue may also be damaged. In addition, approximately 25% of XP patients also develop abnormalities of the nervous system manifesting as progressive neuro-degeneration with hearing loss. People with XP have a 10,000-fold increased risk for developing skin cancer including basal cell carcinoma, squamous cell carcinoma and melanoma. They also have a 2000-fold increased risk for cancer of the eye and surrounding ocular tissues. These symptoms appear early in life, typically before age 10 years. This case is being presented to highlight the rarity of a case of xeroderma pigmentosum with squamous cell carcinoma in a ten year old child.

  20. Reverse shoulder arthroplasty in young patient with achondroplasia - Ten year follow up: Case report.

    Science.gov (United States)

    van den Broek, M; Verborgt, O; Declercq, G

    2017-11-01

    Skeletal dysplasia in achondroplasia can affect all body joints - including the glenohumeral joint - and is prone to develop to degenerative osteoarthritis (OA). This may cause pain and mobility problems at young age. Surgical treatment is challenging due to the dysplastic anatomy of the shoulder joint - with a dysplastic deformed short humerus, a small, hypoplastic medialized glenoid and lateralized acromion - and the long life expectancy of these patients. The indications for reverse shoulder arthroplasty (RSA) evolved during years with rotator cuff tears and rotator cuff arthropathy in combination with or without glenohumeral OA as the main indicator, with good short to mid-term results. Long term results of RSA are rarely found in literature, especially in young patients. The use of a RSA in glenohumeral OA with an intact rotator cuff has rarely been reported. In this case report we present the ten-year clinical and radiographic results of a RSA for the treatment of degenerative OA with glenohumeral dysplasia in a young patient with achondroplasia. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  1. Minimally invasive transaxial lumbosacral interbody fusion: a ten year single-centre experience.

    Science.gov (United States)

    Zeilstra, Dick J; Staartjes, Victor E; Schröder, Marc L

    2017-01-01

    Our aim was to evaluate mid- and long-term results in a cohort of patients who underwent minimally invasive transaxial lumbosacral fixation and to identify clinical and other parameters that can aid in proper patient selection. Over a period of ten years, we assessed 164 patients who had a complete follow-up of a minimum of one year (average 54 months). On follow-up, we recorded clinical status, fusion status, visual analogue scale (VAS), Oswestry Lower Back Pain Disability Index (ODI) scores and patient satisfaction. There were no intra- or peri-operative complications. Overall clinical success rate was 73.8 %. Only sex (female), working status (still working), body mass index (BMI) (lower) and presence of Modic II changes (absent) were correlated with a good result. Transaxial fixation is a safe, minimally invasive technique that can offer good results in patients with single-level degenerative disc disease (DDD) at the lumbosacral level, with minimal operative risk.

  2. Marked seasonality of Cyclospora cayetanensis infections: ten-year observation of hospital cases, Honduras.

    Science.gov (United States)

    Kaminsky, Rina Girard; Lagos, Javier; Raudales Santos, Gabriela; Urrutia, Samuel

    2016-02-04

    Document seasonality occurrence and epidemiologic characteristics of Cyclospora cayetanensis infections during a 10-year period from patients consulting at the University Hospital, Honduras. Retrospective non interventional hospital-based study analyzed laboratory results from the period 2002 to 2011 of fresh and Ziehl-Nielsen carbolfuchsin stained routine stool samples received for parasitologic examination. Sporadically a sample with numerous oocysts was allowed to sporulate in 2.5 % potassium dichromate confirming the presence of bi-cystic bi-zoic oocysts. A total of 35,157 fecal samples were examined during a ten-year span, of which a third (28.4 %) was stained by the Ziehl-Neelsen carbolfuchsin method diagnosing a total of 125 (1.3 %) C.cayetanensis infections. A statistically significant apparent seasonality was observed most years during May to August (range p < 0.036-0.001), with 83.3 % of 125 cases occurring in those rainy months. All C. cayetanensis cases came from urban poor neighborhoods; male/female relation was 1:1 except in 2006, when all patients were females (p = 0.05; r(2) = 22,448). Forty four point eight percent of the stool samples were diarrheic or liquid and 65.6 % infections were identified in children 10 years old or less. Enteric helminths and protozoa co-infected Cyclospora positive patients in 52 instances.: 8 % Ascaris lumbricoides, 8 % Giardia duodenalis, 23.2 % Blastocystis spp. and less frequently Entamoeba histolytica/E. dispar, Strongyloides stercoralis, and Trichuris trichiura. Results suggest a seasonal pattern for Cyclospora infections diagnosed in a clinical setting during the rainy months in Tegucigalpa and surrounding areas. Community studies should be conducted to support or dispute these observations.

  3. Cognitive and executive functions in anorexia nervosa ten years after onset of eating disorder.

    Science.gov (United States)

    Gillberg, I Carina; Råstam, Maria; Wentz, Elisabet; Gillberg, Christopher

    2007-02-01

    In a longitudinal study, the authors explore the course of general cognition in anorexia nervosa (AN) over time and compare general cognitive problems, executive function deficits, attentional problems and visuomotor dysfunctions across AN individuals and healthy controls. A community-based sample of adolescent onset AN cases (n=40-47) was contrasted with an age-, sex- and school matched comparison group (n=47-51) on the Wechsler Adult Intelligence Scale-Revised, the Wisconsin Card Sorting Test and Luria word recall test at a mean age of 24 years. Only two of the cases tested were underweight at the time of the study. The Wechsler scale had also been administered when the groups had a mean age of 21 years. There were few differences across the two groups even though the comparison group performed significantly better on the Object Assembly subtest of the WAIS-R. IQ increased slightly but significantly over time in both groups. There was no relationship between level of starvation and poor results on tests in the AN group. A subgroup of the subjects had autism spectrum disorders. In this subgroup there were cases with test profiles similar to those observed in autism and Asperger syndrome, just as there had been on testing three years previously. Ten years after AN onset, the former AN cases showed no major neuropsychological deficits. A subgroup with autistic features had test profiles similar to those observed in autism spectrum disorders. The AN group as a whole showed poor results on the object assembly subtest indicating weak central coherence with a tendency to focus on details at the expense of configural information. This cognitive style may account for their obsession with details, with implications for psychoeducational approaches in treatment programmes/interventions.

  4. The Upper Atmosphere Research Satellite (UARS): Ten successful years of observations

    Science.gov (United States)

    Johnson, J.; Ahmad, S.; Serafino, G.; Jackman, C.

    As a major element in NASA's comprehensive Upper Atmosphere Research Program, the Upper Atmosphere Research Satellite (UARS) was launched on September 12, 1991, into a circular orbit at an altitude of approximately 570 km with an inclination of 57 degrees. Ten instruments were flown aboard UARS with the goal to understand 1) the response of the upper atmospheric chemistry to natural and human perturbations, 2) the chemical processes and dynamics that control upper atmosphere structure and variability, and 3) couplings of the lower and upper atmosphere that play a major role in defining climate and climate variability. UARS with its ten unique instruments has been the first satellite to provide high quality, simultaneous global measurements of the chemistry, dynamics, and energetics of the stratosphere, mesosphere, and lower thermosphere. After 10 years of successful data collection (far exceeding the originally projected lifetime of 3 years), the official mission ended in September 2001. However, seven instruments aboard UARS are still operational and six regularly take measurements. Standard UARS products consisting of measurements of atmospheric internal structure (trace constituents, physical dynamics, radiative emission, thermal structure, density) and measurements of the external influences acting upon the upper atmosphere (solar radiation and charged particle precipitation) and ancillary data consisting of model analyses and correlative measurements are archived at the Goddard Earth Sciences DAAC. Data products from heritage sensors including Nimbus-4 Backscatter Ultraviolet Spectrometer (BUV), Nimbus-7 Solar Backscatter Ultraviolet Spectrometer (SBUV) and a series of Total Ozone Mapping Spectrometer (TOMS) instruments are also archived at the Goddard DAAC. The continuity of ozone, other trace species, and solar UV measurements will be maintained with the launch of the Aura spacecraft in early 2004 (the third mission in NASA's Earth Observing System program

  5. Ten years of negotiating rights around maternal health in Uttar Pradesh, India.

    Science.gov (United States)

    Dasgupta, Jashodhara

    2011-12-16

    Preventable maternal mortality and morbidity have been globally recognized as human rights issues. Maternal mortality in India is among the highest in the world, and reflects inequity in access to healthcare: women from certain states as well as poorer women and less literate women appear to be significantly disadvantaged. The government of India has been attempting to improve maternal outcomes through a cash transfer within the National Rural Health Mission to encourage women to come to hospitals for childbirth. This paper reviews documents of the last ten years describing the experiences of a Non-Governmental Organisation, SAHAYOG, in working with a civil society platform, the Healthwatch Forum, to develop 'rights based' strategies around maternal health. The paper builds an analysis using recent frameworks on accountability and gendered rights claiming to examine these experiences and draw out lessons regarding rights claiming strategies for poor women. The examination of documents over the last ten years indicates defined phases of development in the evolution of SAHAYOG's understanding and of the shifts in strategy among SAHAYOG and its close allies, and responses by the state. The first three stages depict the deepening of SAHAYOG's understanding of the manner in which poor and marginalized women negotiate their access to health care; the fourth stage explores a health system intervention and the challenges of working from within civil society in alliance with poor and marginalized women. The findings from SAHAYOG's experiences with poor Dalit women in Uttar Pradesh reveal the elements of social exclusion within the health system that prevent poor and marginalized women from accessing effective lifesaving care. Creating a voice for the most marginalised and carving space for its articulation impacts upon the institutions and actors that have a duty to meet the claims being made. However, given the accountability deficit, the analysis indicates the importance

  6. A field like today's? The strength of the geomagnetic field 1.1 billion years ago

    Science.gov (United States)

    Sprain, Courtney J.; Swanson-Hysell, Nicholas L.; Fairchild, Luke M.; Gaastra, Kevin

    2018-02-01

    Paleomagnetic data from ancient rocks are one of the few types of observational data that can be brought to be bear on the long-term evolution of Earth's core. A recent compilation of paleointensity estimates from throughout Earth history has been interpreted to indicate that Earth's magnetic field strength increased in the Mesoproterozoic (between 1.5 and 1.0 billion years ago), with this increase taken to mark the onset of inner core nucleation. However, much of the data within the Precambrian paleointensity database are from Thellier-style experiments with non-ideal behavior that manifests in results such as double-slope Arai plots. Choices made when interpreting these data may significantly change conclusions about long-term trends in the intensity of Earth's geomagnetic field. In this study, we present new paleointensity results from volcanics of the ˜1.1 billion-year-old North American Midcontinent Rift. While most of the results exhibit non-ideal double-slope or sagging behavior in Arai plots, some flows have more ideal single-slope behavior leading to paleointensity estimates that may be some of the best constraints on the strength of Earth's field for this time. Taken together, new and previously published paleointensity data from the Midcontinent Rift yield a median field strength estimate of 56.0 ZAm2—very similar to the median for the past 300 million years. These field strength estimates are distinctly higher than those for the preceding billion years after excluding ca. 1.3 Ga data that may be biased by non-ideal behavior—consistent with an increase in field strength in the late Mesoproterozoic. However, given that ˜90 per cent of paleointensity estimates from 1.1 to 0.5 Ga come from the Midcontinent Rift, it is difficult to evaluate whether these high values relative to those estimated for the preceding billion years are the result of a stepwise, sustained increase in dipole moment. Regardless, paleointensity estimates from the Midcontinent

  7. EFS Centre-Atlantique donor's biobank: Ten years of samples usage.

    Science.gov (United States)

    Sapey, T; Py, J-Y; Barnoux, M; Tessier, M; Dehaut, F

    2016-05-01

    The French Establishment of Blood Centre Atlantique (EFSCA) is one of the French regional blood transfusion centers. Donor's biobank is a mandatory activity leading to the storage of biological samples taken from the blood donor. Samples of each blood donation are preserved for a 5-year period at Châteauroux in the form of two straws of 500microliters stored in liquid nitrogen. The aim of this study was to analyze the samples usage by studying quantitative, qualitative and economic criteria. We analyzed all the requests of stored blood samples from 2005 to 2014. They were coming either from the blood donor qualification laboratory (BDQL), in order to perform complementary tests, or from hemovigilance inquiry. Among the blood donation samples, 2,144,636 (whole blood, plasma or platelets apheresis) were preserved during these ten years. During this period, 548 (0.025%) requests for samples were received; 78% were in relation with a request of the BDQL and 22% in relation with a request of hemovigilance. For the straws, the mean exit delay with regard to the blood donation date was 11.5 months (2-55). The cost of samples exit includes only working hours of a laboratory technician. On average, the annual working time dedicated to this activity was 23h. Also, the average price for one-year issuing activity was 620.31 euros. In our study, the donor's biobank was little used. The part of hemovigilance was weak but essential for the blood safety. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  8. Ten years of RELEA: achievements and challenges for astronomy education development

    Science.gov (United States)

    Bretones, Paulo Sergio; Jafelice, Luiz Carlos; Horvath, Jorge Ernesto

    2015-08-01

    When an area of education, and more particularly the research within this area, is aimed to development, a basic requirement is the existence of a regular publication that accounts for the scientific production in that area. This study aims to analyze 10 years of Latin-American Journal of Astronomy Education (RELEA). Publishing policies of the RELEA and their context are discussed in relation to submission, refereeing and publication. The 75 articles published in 18 editions are analyzed and classified by: year of publication, edition, the authors' institutions, school level, study focus and content. The results present trends and shortcomings of the production. A comparison with the number of articles published in other Brazilian journals of education and an analysis of the international scene in relation to other type publications along these ten years is made. Given that this journal is now consolidated, its future prospects in the international landscape are further considered. The challenges related to article submission are discussed: how to increase their number, the submission of Latin American countries, and how to bring in the issues and subjects not addressed until now. It is also considered the possibility of encouraging graduate studies, new lines of research in astronomy education, and dissemination of material in schools and universities for teachers and students. Finally, future possibilities are discussed given the IAU development programs. For example, more article submission from Portuguese-speaking countries with the support of Regional Nodes and Language Expertise Centers, and opportunities for volunteer IAU members and global projects for the development of astronomy education.

  9. Organisation and Management of a Complete Bachelor Degree Offered Online at the University of Milan for Ten Years

    Science.gov (United States)

    Milani, Manuela; Papini, Sabrina; Scaccia, Daniela; Scarabottolo, Nello

    2014-01-01

    This paper is aimed at presenting some reflections on organisation and management of SSRI online: an e-learning initiative started at the University of Milan (Italy) in the academic year 2004/05 and offered to students over the last ten years. The initiative consisted in implementing the online version of an already existing three-year bachelor…

  10. Early detection, early symptom progression and symptomatic remission after ten years in a first episode of psychosis study

    DEFF Research Database (Denmark)

    Simonsen, Erik; ten Velden Hegelstad, Wenche; Haahr, Ulrik Helt

    2013-01-01

    years, 50% of patients were in symptomatic remission. Non-remission was predicted by positive symptoms at inclusion and during the first year of treatment. Of individual symptoms only hallucinations were significantly predictive of ten-year non-remission. Early symptom differences were not reflected...

  11. Modeling the Office of Science ten year facilities plan: The PERI Architecture Tiger Team

    International Nuclear Information System (INIS)

    Supinski, Bronis R de; Gamblin, Todd; Schulz, Martin

    2009-01-01

    The Performance Engineering Institute (PERI) originally proposed a tiger team activity as a mechanism to target significant effort optimizing key Office of Science applications, a model that was successfully realized with the assistance of two JOULE metric teams. However, the Office of Science requested a new focus beginning in 2008: assistance in forming its ten year facilities plan. To meet this request, PERI formed the Architecture Tiger Team, which is modeling the performance of key science applications on future architectures, with S3D, FLASH and GTC chosen as the first application targets. In this activity, we have measured the performance of these applications on current systems in order to understand their baseline performance and to ensure that our modeling activity focuses on the right versions and inputs of the applications. We have applied a variety of modeling techniques to anticipate the performance of these applications on a range of anticipated systems. While our initial findings predict that Office of Science applications will continue to perform well on future machines from major hardware vendors, we have also encountered several areas in which we must extend our modeling techniques in order to fulfill our mission accurately and completely. In addition, we anticipate that models of a wider range of applications will reveal critical differences between expected future systems, thus providing guidance for future Office of Science procurement decisions, and will enable DOE applications to exploit machines in future facilities fully.

  12. SPIE Smart Structures Product Implementation Award: a review of the first ten years

    Science.gov (United States)

    Anderson, Eric H.; Sater, Janet M.

    2007-04-01

    The research field of smart materials and structures has been a distinct entity for two decades. Over the past ten years, the SPIE Industrial and Commercial Applications Conference has presented a Smart Structures Product Implementation Award at its annual symposium. This paper revisits the nine winning entries to date (1998-2007) and updates their status. The paper begins with a brief description of the original and current intent of the award and follows with a short overview of the evolution of smart structures, from research to products. The winning teams and their respective products are then described. The current status of the products is discussed based on publicly available information and input from the respective companies. Note however that it is not the purpose of the paper to rank the product winners in terms of success or sales. The paper concludes with an assessment of the larger trends in productization of smart structures technologies. The application "form" for the award as well as the evaluation criteria and suggestions for improving award application packages can be found in the appendix.

  13. Dinosaurs in decline tens of millions of years before their final extinction

    Science.gov (United States)

    Sakamoto, Manabu; Benton, Michael J.

    2016-05-01

    Whether dinosaurs were in a long-term decline or whether they were reigning strong right up to their final disappearance at the Cretaceous-Paleogene (K-Pg) mass extinction event 66 Mya has been debated for decades with no clear resolution. The dispute has continued unresolved because of a lack of statistical rigor and appropriate evolutionary framework. Here, for the first time to our knowledge, we apply a Bayesian phylogenetic approach to model the evolutionary dynamics of speciation and extinction through time in Mesozoic dinosaurs, properly taking account of previously ignored statistical violations. We find overwhelming support for a long-term decline across all dinosaurs and within all three dinosaurian subclades (Ornithischia, Sauropodomorpha, and Theropoda), where speciation rate slowed down through time and was ultimately exceeded by extinction rate tens of millions of years before the K-Pg boundary. The only exceptions to this general pattern are the morphologically specialized herbivores, the Hadrosauriformes and Ceratopsidae, which show rapid species proliferations throughout the Late Cretaceous instead. Our results highlight that, despite some heterogeneity in speciation dynamics, dinosaurs showed a marked reduction in their ability to replace extinct species with new ones, making them vulnerable to extinction and unable to respond quickly to and recover from the final catastrophic event.

  14. Ten-yearly report on operations at the Garigliano nuclear power station

    International Nuclear Information System (INIS)

    1977-01-01

    This document is the final report on operation of the Garigliano Nuclear Power Station as required under the participation contract between Enel and Euratom and refers to the first ten years of commercial operation (1 May 1964-31 December 1973) of the power station. In the decade in question the Garigliano Power Station has assumed an important position in the world spectrum of nuclear energy since it was the first thermal-power reactor in the world to have irradiated considerable quantities of plutonium as a fuel in its own core for the production of energy. An experimental programme on this was started in 1966 with theoretical study of plutonium recycling and was followed by the charging of the Garigliano reactor with some mixed oxide elements (PuO 2 -UO 2 ) in 1968 and 1970. The excellent performance of these prototype elements, which among other things were examined in detail at the end of each radiation cycle, prompted Enel to decide in favour of the use of entire batches of recycled fuel elements of the PuO 2 -UO 2 type in the reactor from 1975 onwards

  15. Ten years after "Worrying trends in econophysics": developments and current challenges

    Science.gov (United States)

    Ormerod, Paul

    2016-12-01

    Econophysics has made a number of important additions to scientific knowledge. Yet it continues to lack influence with both economists and policy makers. Ten years ago, I and three other economists sympathetic to econophysics wrote a paper on worrying trends within the discipline. For example, its lack of awareness of the economics literature, and shortfalls in the use of statistical analysis. These continue to be obstacles to wider acceptance by economists. Like all agents, policy makers respond to incentives, and economists understand this very well. Much of the econophysics community appears to think that simply doing good science is sufficient to have the work recognised, rather than relating to the motivations and incentives of policy makers. Nevertheless, econophysics now has three major opportunities to advance knowledge in areas where policy makers perceive weaknesses in what they are presented with by economists. All can benefit from the analysis of Big Data. The first is a core model of agent behaviour which is more relevant to cyber society than the rational agent model of economics. Second, extending our understanding of the business cycle, primarily by incorporating the importance of networks into models. Third, devising proper measures of output in cyber society.

  16. Ten-year operational dust forecasting - Recent model development and future plans

    Energy Technology Data Exchange (ETDEWEB)

    Kallos, G; Spyrou, C; Astitha, M; Mitsakou, C; Solomos, S; Kushta, J; Pytharoulis, I; Katsafados, P; Mavromatidis, E; Papantoniou, N; Vlastou, G [University of Athens, School of Physics, Atmospheric Modeling and Weather Forecasting Group - UOA/AM and WFG, University Campus, Bldg. PHYS-V, Athens 15784 (Greece)], E-mail: kallos@mg.uoa.gr

    2009-03-01

    The Sahara desert is one of the major sources of mineral dust on Earth, producing up to 2x10{sup 8} t yr-{sup 1}. A combined effort has been devoted during the last ten years at the University of Athens (UOA) from the Atmospheric Modeling and Weather Forecasting Group (AM and WFG) to the development of an analysis and forecasting tool that will provide early warning of Saharan dust outbreaks. The developed tool is the SKIRON limited-area forecasting system, based on the Eta limited area modeling system with embedded algorithms describing the dust cycle. A new version of the model is currently available, with extra features like eight-size particle bins, radiative transfer corrections, new dust source identification and utilization of rocky soil characterization and incorporation of more accurate deposition schemes. The new version of SKIRON modeling system is coupled with the photochemical model CAMx in order to study processes like the shading effect of dust particles on photochemical processes and the production of second and third generation of aerosols. Moreover, another new development in the AM and WFG is based on the RAMS model, with the incorporation of processes like dust and sea-salt production, gas and aqueous phase chemistry and particle formation. In this study, the major characteristics of the developed (and under development) modeling systems are presented, as well as the spatiotemporal distribution of the transported dust amounts, the interaction with anthropogenically-produced particles and the potential implications on radiative transfer.

  17. Ten years' experience in determining internal contamination among plutonium laboratory workers

    International Nuclear Information System (INIS)

    Deworm, J.; Fieuw, G.

    1976-01-01

    Glove boxes in plutonium laboratories are fitted with ''sniffers'' (air samplers), which evaluate atmospheric contamination. The results of the measurements over a ten-year period of operation are available, and cases of detection in this way of air contamination exceeding the maximum permissible concentrations are exceptional. During contamination aerodynamic particle diameters of 1 - 4 μm were measured. The concentration and characteristics of the aerosol have made it possible to ascertain the inhalable fraction and to estimate the pulmonary and systemic burden in workers. The workers exposed in the laboratories undergo a urine test each month. The results obtained show that there is little risk of internal contamination without the person concerned being aware of an abnormal situation. In the majority of cases it is possible to take proper precautions and to collect the data necessary for evaluating the body burden. Three cases of specific contamination are examined in detail: contamination by plutonium and americium from a non-identified source, detected by routine urine analysis; contamination by inhalation of plutonium; an injury to the left forefinger, accompanied by plutonium contamination. (author)

  18. Psychoanalysis today

    Science.gov (United States)

    FONAGY, PETER

    2003-01-01

    The paper discusses the precarious position of psychoanalysis, a therapeutic approach which historically has defined itself by freedom from constraint and counted treatment length not in terms of number of sessions but in terms of years, in today's era of empirically validated treatments and brief structured interventions. The evidence that exists for the effectiveness of psychoanalysis as a treatment for psychological disorder is reviewed. The evidence base is significant and growing, but less than might meet criteria for an empirically based therapy. The author goes on to argue that the absence of evidence may be symptomatic of the epistemic difficulties that psychoanalysis faces in the context of 21st century psychiatry, and examines some of the philosophical problems faced by psychoanalysis as a model of the mind. Finally some changes necessary in order to ensure a future for psychoanalysis and psychoanalytic therapies within psychiatry are suggested. PMID:16946899

  19. Budget-in-brief, fiscal year 1998: Energy for today and tomorrow

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-09-01

    This document provides a brief overview of how the Energy Efficiency and Renewable Energy programs plan to improve: environmental quality, energy security, public health, and economic productivity. Substantial opportunities remain to improve the nation`s energy future without incurring high costs or imposing overly restrictive regulations. Current restructuring of electricity markets and international agreements on global climate change are focusing attention on some of these opportunities. With energy demand in countries such as China and India projected to grow exponentially in coming decades, US exports of clean energy technologies will be important for mitigating world environmental degradation and climate change--and for fostering strong US industries in sustainable energy products and services. Enabling developing countries to grow without the negative consequences of pollution is one of the most valuable forms of leadership the US can exercise in world affairs in the years ahead.

  20. Ten Windows Into the Meteorite Flux to Earth During the Past 500 Million Years

    Science.gov (United States)

    Schmitz, B.

    2017-12-01

    Almost nothing is known about the variations through deep time in the types of meteorites arriving at Earth. In an ongoing project we are searching ancient sediments from ten different time periods through the Phanerozoic for relict extraterrestrial spinel grains from micrometeorites (Schmitz, 2013). Samples, 300-1500 kg large, of slowly formed pelagic limestone are dissolved in acids leaving a residue of extraterrestrial spinels. The time periods studied include the middle Cambrian, Ordovician before and after the breakup of the L-chondrite parent body, late Silurian, late Devonian, middle Jurassic, early and late Cretaceous, early Paleocene and late Eocene. The approach builds on complex methodological considerations and a thorough understanding also of the spinel fraction in recent meteorites is necessary. In order to obtain some insights into the changes in the meteorite flux carefully calibrated analyses of the isotopic and elemental composition of the recovered spinel grains as well as consistent data treatment is required for the different time windows. Our results indicate that the background meteorite flux has changed significantly through the Phanerozoic. The results so far suggest that there may have been a gradual long-term (on the order of hundred million years) turnover in the meteorite flux from dominance of achondrites in the early Phanerozoic to ordinary chondrites in the late Phanerozoic interrupted by short-term (a few million years) meteorite cascades from single asteroid breakup events. This scenario may change, however, as results from additional time windows emerge. B. Schmitz (2013) Extraterrestrial spinels and the astronomical perspective on Earth's geological record and evolution of life: Chemie der Erde 73:117-145.

  1. Ten Years of Hydrographic Variability Off Central California During the Upwelling Season

    National Research Council Canada - National Science Library

    Baltz, Kenneth

    1997-01-01

    Analysis of mean conditions and variability during the upwelling season off central California was performed on data sets of buoy and shoreline surface measurements and CTD data from ten annual NMFS surveys (1987-1996...

  2. Ten-year follow-up of thyroid epidemiology in Slovenia after increase in salt iodization

    Science.gov (United States)

    Zaletel, Katja; Gaberšček, Simona; Pirnat, Edvard; Krhin, Blaž; Hojker, Sergej

    2011-01-01

    Aim To assess iodine supply and follow thyroid epidemiology for ten years after an iodine increase from 10 to 25 mg of potassium iodide per kilogram of salt in 1999. Methods In 2002 and 2003, we determined the thyroid size by palpation and ultrasound and measured urinary iodine concentration (UIC) in 676 schoolchildren from 34 schools throughout Slovenia. From 1999 to 2009, we followed the incidence of diffuse and nodular goiter, thyroid autonomy, Graves’ disease, and Hashimoto’s thyroiditis among adults in the stable catchment area of the University Medical Centre Ljubljana with 1 000 000 inhabitants. Results In children, only 1% had a goiter grade 2 (visible and palpable thyroid gland), median thyroid volume was 5.8 mL, and median UIC was 148 µg/L. In adults, the incidence of diffuse goiter and thyroid autonomy decreased significantly (2009 vs 1999, rate ratio [RR], 0.16; 95% confidence interval [CI], 0.12-0.21 and RR, 0.73; 95% CI, 0.62-0.86, respectively), with a lower incidence in younger participants in 2009 (P < 0.001). The incidence of multinodular goiter and solitary nodule increased (2009 vs 1999, RR, 1.55; 95% CI, 1.35-1.79 and RR, 1.72; 95% CI, 1.49-1.99, respectively). No long-term changes were observed for Graves’ disease (2009 vs 1999, RR, 0.95; 95% CI, 0.81-1.13), while the incidence of Hashimoto’s thyroiditis increased strongly (2009 vs 1999, RR, 1.86; 95% CI, 1.64-2.12). Conclusions The change from mildly deficient to sufficient iodine supply was associated with a marked change in the incidence of thyroid epidemiology – a significant decline in the incidence of diffuse goiter and thyroid autonomy and a marked increase in the incidence of Hashimoto’s thyroiditis. PMID:21990079

  3. Ten years experience of managing the primary tumours in patients with stage IV colorectal cancers.

    Science.gov (United States)

    Aslam, Muhammad Imran; Kelkar, Ashish; Sharpe, David; Jameson, John Stuart

    2010-01-01

    Approximately 20% of patients with colorectal cancer have metastases at the time of presentation. Such patients are often offered systemic chemotherapy but debate continues as to whether these patients benefit from resection of the primary tumour. We describe our ten years experience of managing the primary tumours in patients with stage IV colorectal cancer. The aim of this study was to describe the overall survival of patients undergoing surgery in these circumstances and to determine whether any prognostic indicators could be identified. 920 consecutive patients presenting with stage IV colorectal cancer disease were identified from the Leicester Colorectal Cancer database. Patients undergoing resection of the primary tumour (Resection Group) with the residual metastatic disease were compared to those patients who had not their primary tumour excised (Non-Resection Group). Various different variables in two groups were compared by using Mann-Whitney U test. Kaplan-Meier survival analysis and log-rank test were used to compare the overall survivals. Univariate analysis was performed for each group to elicit the significant prognostic factors whereas Cox regression model was used to identify the independent predictors of overall survival. The Kaplan-Meier survival analysis of two groups showed prolonged survival for Resection Group compared to the Non-Resection Group (median; 14.5 Vs 5.83 months, p = fixity, ASA grade, mode of surgery, post-operative chemotherapy and sites of metastasis as significant factors (p fixity (p = 0.012) and lymph nodal involvement (p = 0.042) were independent predictors for overall survival. Treatment with post-operative chemotherapy and a smaller volume of liver metastases were associated with prolonged survival (p fixity and ASA grade can help to decide the patients who will benefit from surgery. Copyright (c) 2010 Surgical Associates Ltd. All rights reserved.

  4. Ten years of METEOR (an international rheumatoid arthritis registry): development, research opportunities and future perspectives.

    Science.gov (United States)

    Bergstra, Sytske Anne; Machado, Pedro M M C; van den Berg, Rosaline; Landewé, Robert B M; Huizinga, Tom W J

    2016-01-01

    Ten years ago, the METEOR tool was developed to simulate treatment-to-target and create an international research database. The development of the METEOR tool and database, research opportunities and future perspectives are described. The METEOR tool is a free, online, internationally available tool in which daily practice visits of all rheumatoid arthritis patients visiting a rheumatologist can be registered. In the tool, disease characteristics, patient- and physician-reported outcomes and prescribed treatment could be entered. These can be subsequently displayed in powerful graphics, facilitating treatment decisions and patient-physician interactions. An upload facility is also available, by which data from local electronic health record systems or registries can be integrated into the METEOR database. This is currently being actively used in, among other countries, the Netherlands, Portugal and India. Since an increasing number of hospitals use electronic health record systems, the upload facility is being actively used by an increasing number of sites, enabling them to benefit from the benchmark and research opportunities of METEOR. Enabling a connection between local registries and METEOR is a well established but time-consuming process for which an IT-specialist of METEOR and the local registry are necessary. However, once this process has been finished, data can be uploaded regularly and relatively easily according to a pre-specified format. The METEOR database currently contains data from >39,000 patients and >200,000 visits, from 32 different countries and is ever increasing. Continuous efforts are being undertaken to increase the quality of data in the database. Since METEOR was founded 10 years ago, many rheumatologists worldwide have used the METEOR tool to follow-up their patients and improve the quality of care they provide to their patients. Combined with uploaded data, this has led to an extensive growth of the database. It now offers a unique

  5. Survival of the Scandinavian total ankle replacement (STAR): results of ten to nineteen years follow-up.

    Science.gov (United States)

    Frigg, Arno; Germann, Ursula; Huber, Martin; Horisberger, Monika

    2017-10-01

    The purpose of this study was to evaluate survival and clinical outcome of the Scandinavian total ankle replacement (STAR) prosthesis after a minimum of ten years up to a maximum of 19 years. Fifty STAR prostheses in 46 patients with end stage ankle osteoarthritis operated between 1996 and 2006 by the same surgeon (MH) were included. Minimal follow-up was ten years (median 14.6 years, 95% confidence interval [CI] 12.9-16.4). Clinical (Kofoed score) and radiological assessments were taken before the operation and at one, ten (+2), and 16 (±3) years after implantation. The primary endpoint was defined as exchange of the whole prosthesis or conversion to arthrodesis (def. 1), exchange of at least one metallic component (def. 2), or exchange of any component including the inlay (due to breakage or wear) (def. 3). Survival was estimated according to Kaplan-Meier. Further reoperations related to STAR were also recorded. The ten year survival rate was (def. 1) 94% (CI 82-98%), (def. 2) 90% (CI, 77-96%), and (def. 3) 78% (CI 64-87%). The 19-year survival rate was (def. 1) 91% (CI 78-97%), (def. 2) 75% (CI 53-88%), and (def. 3) 55% (CI 34-71%). Considering any re-operations related to STAR, 52% (26/50) of prostheses were affected by re-operations. Mean pre-operative Kofoed score was 49, which improved to 84 after one year (n = 50), to 90 after ten years (n = 46), and to 89 after 16 years (n = 28). The survival rate for def. 1 and 2 was high. However, re-operations occurred in 52% of all STAR prosthesis. Retrospective cohort study, evidence Level 4.

  6. The Ten Most Important Reading Research Studies Published during the Last 25 Years.

    Science.gov (United States)

    Peterson, Gordon

    The ten reading research studies published since 1955 and deemed by the author "most important" in terms of quality, originality, and applicability to elementary reading instruction are described in this report. Discussed are studies on reading approaches by Russell Stauffer and by Neville Bennett; a study on reading readiness by Audrey…

  7. What do you want to be in ten years? - Advising meteorology students in the post-Twister era

    Science.gov (United States)

    Snow, J. T.; Hempe, M.

    2012-12-01

    "What do you want to be in ten years?' This is a question we ask our students, freshmen and transfer, when they first arrive in the College student services center. Often the answer is "I don't know. I just want to be in meteorology." This response leads to a discussion of career opportunities in meteorology and related fields, including what might be called faux-careers, such as professional storm chasing and weather tour operations. (Students often have been misled by what they have seen in television shows.) Many students arrive on our doorstep with their heart set on a degree in meteorology, but lack knowledge of what the field is about or how challenging a meteorology degree program really is. We find ourselves spending a great deal of time convincing students that they need to explore the real opportunities in meteorology and related fields, which are many. Fortunately, because of the concentration of University and federal weather organizations in the National Weather Center and private sector weather companies in adjacent buildings, we are able to show concrete examples of real careers by means of tours, job shadowing, and introductions to alumni employed in these organizations. Also, as the students' progress in their studies, they discover the many opportunities for undergraduate employment, research experiences, and internships in these same organizations, through which they gain an appreciation for what constitutes a real career in modern meteorology. Further, many of today's careers in meteorology require a broad, global perspective. Unfortunately, many meteorology students have not traveled widely, but again have only seen what the media provides about distant lands and peoples. Accordingly, we encourage our undergraduate students to take advantage of our unique opportunities for overseas experiences in meteorology. Through arrangements with the met programs at the University of Reading (England), Monash University (Australia), and University of

  8. Nuclear Society of Russia: Ten years in the world nuclear community

    International Nuclear Information System (INIS)

    Ponomarev-Stepnoi, N.N.; Gagarinski, A.Yu.

    2000-01-01

    A nuclear society, which is a nongovernmental organization of nuclear professionals, appeared in the Soviet Union at the end of the 1980s--when social conditions for such a society had matured. Deep changes in the entire country's social consciousness had promoted the specialists understanding of the need to unite in order to overcome the nuclear community's dissociation, the monopoly of the nuclear ministry, and the secrecy syndrome of all nuclear issues. The new public association announced the guiding principles of its activities to be openness and glasnost and completeness and truthfulness of information supplied to decision makers and to the society as a whole. Important to the information system of the NSR are topical meetings and seminars on quite varied but always actual problems of nuclear energy use, often with foreign participation. The variety of these NSR meeting subjects is illustrated by the titles of several meetings of the last 2 yr: Safety Culture in Nuclear Power, Youth and the Plutonium Challenge, Nuclear Fuel for Mankind, Nuclear Power in Space, Radiation Legacy of the Former-USSR, the Murmansk International Forum Nuclear Fleet and Ecology, and many others. A special place among NSR seminars belongs to the annual meeting, Nuclear Energy and Public Opinion, the Russian analog of the European PIME conference. Starting from distribution of ENS periodicals--the Nuclear Europe Worldscan magazine and Nucleus information sheet--among its members, the NSR soon began publishing its own Informational Bulletin (since 1989). Note that in the first years of the Nuclear Society's existence, it has been possible to publish periodicals, conference proceedings, and even books in English. Unfortunately, financial difficulties of the last years have frozen this most useful activity, which the NSR, however, hopes to resume. In the last period, the materials of the international information agency NucNet, which provides both regular information for the analysis of

  9. Creative Climate: A global ten-year communications, research and learning project about environmental change

    Science.gov (United States)

    Brandon, M. A.; Smith, J.

    2010-12-01

    The next ten years have been described by influential science and policy figures as ‘the most important in human history’. Many believe that the actions taken will decide whether we catastrophically change the atmosphere and eradicate our fellow species or find an alternative, less-damaging development path. But communications and public engagement initiatives have tended to focus on near term impacts or debates - whether they emphasise hazards, or trumpet ‘solutions’. There are signs of diminishing returns on communications and public engagement efforts, and serious obstacles to engaging around 40% of publics in e.g. the US and the UK. The Creative Climate web project takes a new approach, inviting people to see humanity’s intellectual and practical journey with these issues as an inspiring, dynamic and unfolding story. We are inviting people to join us in building a huge living archive of experiences and ideas that respond to these issues. The website will collect thoughts and stories from doorstep to workplace, from lab to garden; from international conference to community meeting - from all over the world. The body of diaries lie at the core of the project, but these are supplemented by the offer of free online learning resources and broadcast-quality audio and video materials. The project is experimental in terms of its scope, its approach to environmental communications and debate and in its use of media. It works with formal partners, including the BBC, yet also makes the most of the opportunities for user generated content to create a rich multimedia resource that can support research, learning and engagement. The design of the project is informed by environmental social science and communications research, and by an awareness of the unfolding potential of Internet based communications to support social change. It is also intended that the Creative Climate platform will develop so as to serve researchers by offering an open resource of qualitative

  10. Clinical characteristics and prognosis of childhood rhabdomyosarcoma: a ten-year retrospective multicenter study.

    Science.gov (United States)

    Ma, Xiaoli; Huang, Dongsheng; Zhao, Weihong; Sun, Liming; Xiong, Hao; Zhang, Yi; Jin, Mei; Zhang, Dawei; Huang, Cheng; Wang, Huanmin; Zhang, Weiping; Sun, Ning; He, Lejian; Tang, Jingyan

    2015-01-01

    Rhabdomyosarcoma (RMS) is the most frequent soft tissue sarcoma in children. We have retrospectively explored the treatment results of childhood RMS and identified prognostic factors in multicenter in China, in order to lay the foundation for further multicenter study. This retrospective study was carried out analyzing the medical records of 161 patients with the pathological diagnosis of RMS from January, 2001 to February, 2014 at 5 large cancer centers in China. The data was reviewed clinico-epidemiological factors. Age, gender, histology type, primary site, tumor size, intergroup rhabdomyosarcoma study (IRS) group and results of treatments were evaluated. Patients were followed up to Dec 31, 2014. The median age of our patients was 51 months. 10.5% of our patients were infants. The genitourinary system was the most common primary site of tumor (43.5%). The proportion of primary site of head and neck except parameningeal, at 28.2% (42 cases), while the proportion of parameningeal region was 4.6% (7 cases). The histological findings were as follows: 130 cases (80.7%) with embryonal, 19 cases (11.9%) with alveolar and 5 cases (3.1%) with botryoid type. According to the classification system of the IRS group, 1 case (0.6%) was group I, 54 cases (33.5%) were group II, 46 cases (28.6%) were group III and 60 cases (37.3 %) were group IV. 149 patients were treated and followed-up regularly, Patients in Beijing children's hospital (n=95) were enrolled in IRS-II/COG-D9803, D9802 protocols. while the other patients (n=54) started on treatment according to Chinese Anti-cancer Association protocol. There were median time of 51 months for following up, 60 occurred event. The ten-year event free survival rate was 53.4±5.1%, overall survival was 65.3±6.3%. The relations between outcome and age (0.046), primary site (0.022), pathologic subtype (0.013), tumor size (0.008) and IRS group (P=0.000) were associated significantly with event free survival. Among the variables, age (P

  11. Strongly baryon-dominated disk galaxies at the peak of galaxy formation ten billion years ago.

    Science.gov (United States)

    Genzel, R; Schreiber, N M Förster; Übler, H; Lang, P; Naab, T; Bender, R; Tacconi, L J; Wisnioski, E; Wuyts, S; Alexander, T; Beifiori, A; Belli, S; Brammer, G; Burkert, A; Carollo, C M; Chan, J; Davies, R; Fossati, M; Galametz, A; Genel, S; Gerhard, O; Lutz, D; Mendel, J T; Momcheva, I; Nelson, E J; Renzini, A; Saglia, R; Sternberg, A; Tacchella, S; Tadaki, K; Wilman, D

    2017-03-15

    In the cold dark matter cosmology, the baryonic components of galaxies-stars and gas-are thought to be mixed with and embedded in non-baryonic and non-relativistic dark matter, which dominates the total mass of the galaxy and its dark-matter halo. In the local (low-redshift) Universe, the mass of dark matter within a galactic disk increases with disk radius, becoming appreciable and then dominant in the outer, baryonic regions of the disks of star-forming galaxies. This results in rotation velocities of the visible matter within the disk that are constant or increasing with disk radius-a hallmark of the dark-matter model. Comparisons between the dynamical mass, inferred from these velocities in rotational equilibrium, and the sum of the stellar and cold-gas mass at the peak epoch of galaxy formation ten billion years ago, inferred from ancillary data, suggest high baryon fractions in the inner, star-forming regions of the disks. Although this implied baryon fraction may be larger than in the local Universe, the systematic uncertainties (owing to the chosen stellar initial-mass function and the calibration of gas masses) render such comparisons inconclusive in terms of the mass of dark matter. Here we report rotation curves (showing rotation velocity as a function of disk radius) for the outer disks of six massive star-forming galaxies, and find that the rotation velocities are not constant, but decrease with radius. We propose that this trend arises because of a combination of two main factors: first, a large fraction of the massive high-redshift galaxy population was strongly baryon-dominated, with dark matter playing a smaller part than in the local Universe; and second, the large velocity dispersion in high-redshift disks introduces a substantial pressure term that leads to a decrease in rotation velocity with increasing radius. The effect of both factors appears to increase with redshift. Qualitatively, the observations suggest that baryons in the early (high

  12. Cause-Specific Mortality in HIV-Positive Patients Who Survived Ten Years after Starting Antiretroviral Therapy

    Science.gov (United States)

    May, Margaret T.; Vehreschild, Janne; Obel, Niels; Gill, Michael John; Crane, Heidi; Boesecke, Christoph; Samji, Hasina; Grabar, Sophie; Cazanave, Charles; Cavassini, Matthias; Shepherd, Leah; d’Arminio Monforte, Antonella; Smit, Colette; Saag, Michael; Lampe, Fiona; Hernando, Vicky; Montero, Marta; Zangerle, Robert; Justice, Amy C.; Sterling, Timothy; Miro, Jose; Ingle, Suzanne; Sterne, Jonathan A. C.

    2016-01-01

    Objectives To estimate mortality rates and prognostic factors in HIV-positive patients who started combination antiretroviral therapy between 1996–1999 and survived for more than ten years. Methods We used data from 18 European and North American HIV cohort studies contributing to the Antiretroviral Therapy Cohort Collaboration. We followed up patients from ten years after start of combination antiretroviral therapy. We estimated overall and cause-specific mortality rate ratios for age, sex, transmission through injection drug use, AIDS, CD4 count and HIV-1 RNA. Results During 50,593 person years 656/13,011 (5%) patients died. Older age, male sex, injecting drug use transmission, AIDS, and low CD4 count and detectable viral replication ten years after starting combination antiretroviral therapy were associated with higher subsequent mortality. CD4 count at ART start did not predict mortality in models adjusted for patient characteristics ten years after start of antiretroviral therapy. The most frequent causes of death (among 340 classified) were non-AIDS cancer, AIDS, cardiovascular, and liver-related disease. Older age was strongly associated with cardiovascular mortality, injecting drug use transmission with non-AIDS infection and liver-related mortality, and low CD4 and detectable viral replication ten years after starting antiretroviral therapy with AIDS mortality. Five-year mortality risk was AIDS, and transmission via injecting drug use continue to predict higher all-cause and AIDS-related mortality in patients treated with combination antiretroviral therapy for over a decade. Deaths from AIDS and non-AIDS infection are less frequent than deaths from other non-AIDS causes. PMID:27525413

  13. Lessons from the Institute for New Heads (INH) Class of 2006: Ten Headships--134 Years of Hard-Earned Experience

    Science.gov (United States)

    Raphel, Annette; Huber, John; Chandler, Carolyn; Vorenberg, Amy; Jones-Wilkins, Andy; Devey, Mark A.; Holford, Josie; Craig, Ian; Elam, Julie

    2016-01-01

    Ten years ago in July 2006, 64 mostly starry-eyed men and women attended the NAIS Institute for New Heads (INH) in order to learn the ropes of headship. These newly minted heads were filled with enthusiasm, commitment, and passion, along with humility and a bit of healthy trepidation. One core group connected under the careful guidance of…

  14. 78 FR 46552 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year...

    Science.gov (United States)

    2013-08-01

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R08-OAR-2011-0659; FRL-9840-6] Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year Carbon Monoxide Maintenance Plan for Colorado Springs AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule...

  15. 78 FR 41342 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year...

    Science.gov (United States)

    2013-07-10

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R08-OAR-2010-0389; FRL-9831-9] Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year PM 10 Maintenance Plan for Ca[ntilde]on City AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA...

  16. 78 FR 41307 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year...

    Science.gov (United States)

    2013-07-10

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R08-OAR-2010-0389; FRL-9832-1] Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year PM 10 Maintenance Plan for Ca[ntilde]on City AGENCY: Environmental Protection Agency (EPA). ACTION: Direct final rule. SUMMARY...

  17. 78 FR 46861 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year...

    Science.gov (United States)

    2013-08-02

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R08-OAR-2011-0658; FRL-9840-8] Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year Carbon Monoxide Maintenance Plan for Greeley AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY...

  18. 78 FR 57573 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year...

    Science.gov (United States)

    2013-09-19

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R08-OAR-2012-0475; FRL-9901-05-Region 8] Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year PM 10 Maintenance Plan for Aspen AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA...

  19. 78 FR 71550 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year...

    Science.gov (United States)

    2013-11-29

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R08-OAR-2011-0833; FRL-9903-25-Region-8] Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year PM 10 Maintenance Plan for Telluride AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY...

  20. 78 FR 56185 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year...

    Science.gov (United States)

    2013-09-12

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R08-OAR-2011-0708; FRL-9900-87-Region 8] Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year Carbon Monoxide Maintenance Plan for Fort Collins AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed...

  1. 78 FR 78797 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year...

    Science.gov (United States)

    2013-12-27

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R08-OAR-2011-0834; FRL-9904-90-Region 8] Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year PM 10 Maintenance Plan for Pagosa Springs AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule...

  2. Minimum ten-year follow-up of acetabular fracture fixation from the Irish tertiary referral centre.

    LENUS (Irish Health Repository)

    Magill, Paul

    2012-04-01

    Successful outcome from acetabular fracture fixation is multi-factorial. Long-term results are not frequently reported. Pooling such data from high output centres will help progress acetabular fixation. This paper presents the first ten-year data from the Irish tertiary referral centre.

  3. Cause-Specific Mortality in HIV-Positive Patients Who Survived Ten Years after Starting Antiretroviral Therapy

    DEFF Research Database (Denmark)

    Trickey, Adam; May, Margaret T; Vehreschild, Jorg-Janne

    2016-01-01

    OBJECTIVES: To estimate mortality rates and prognostic factors in HIV-positive patients who started combination antiretroviral therapy between 1996-1999 and survived for more than ten years. METHODS: We used data from 18 European and North American HIV cohort studies contributing to the Antiretro......OBJECTIVES: To estimate mortality rates and prognostic factors in HIV-positive patients who started combination antiretroviral therapy between 1996-1999 and survived for more than ten years. METHODS: We used data from 18 European and North American HIV cohort studies contributing...... to the Antiretroviral Therapy Cohort Collaboration. We followed up patients from ten years after start of combination antiretroviral therapy. We estimated overall and cause-specific mortality rate ratios for age, sex, transmission through injection drug use, AIDS, CD4 count and HIV-1 RNA. RESULTS: During 50,593 person...... mortality in models adjusted for patient characteristics ten years after start of antiretroviral therapy. The most frequent causes of death (among 340 classified) were non-AIDS cancer, AIDS, cardiovascular, and liver-related disease. Older age was strongly associated with cardiovascular mortality, injecting...

  4. 76 FR 9786 - NIOSH Dose Reconstruction Program Ten-Year Review-Phase I Report on Customer Service; Request for...

    Science.gov (United States)

    2011-02-22

    ... Reconstruction Program Ten-Year Review--Phase I Report on Customer Service; Request for Public Review and Comment... Review--Phase I Report on Customer Service.'' This publication is part of a review by NIOSH of its... during the program review: The customer service provided by NIOSH in the program. The document can be...

  5. Genotype-environment interaction and stability in ten-year height growth of Norway spruce Clones (Picea abies Karst.).

    Science.gov (United States)

    J.B. St. Clair; J. Kleinschmit

    1986-01-01

    Norway spruce cuttings of 40 clones were tested on seven contrasting sites in northern Germany. Analysis of variance for ten-year height growth indicate a highly significant clone x site interaction. This interaction may be reduced by selection of stable clones. Several measures of stability were calculated and discussed. Characterization of sites by the method of...

  6. [The top ten researches of Chinese ocular trauma research in recent five years].

    Science.gov (United States)

    2015-08-01

    Ten researches that may represent the progress in Chinese ocular trauma related studies were selected through voting by specialists from Chinese Ocular Trauma Society. These researches focused on the following fields: new strategies for the treatment of ocular trauma, study of vitreoretinal surgery and new technique application for severe ocular trauma, establishment of animal modal for basic research of ocular trauma, prevention of infectious endophthalmitis, clinical and basic study of ocular chemical burn, establishment of the public service and research platform of ocular trauma. These studies represented the level and influence of Chinese ocular trauma specialists in the international academic community and they were the landmark studies of our areas of expertise.

  7. Supercomputers Today

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 3; Issue 11. Supercomputers Today - Parallelism is the Name of the Game. V Rajaraman. General Article Volume 3 Issue 11 November 1998 pp 54-68. Fulltext. Click here to view fulltext PDF. Permanent link:

  8. [The top ten researches of Chinese oculoplastic surgery and orbital disease in recent five years].

    Science.gov (United States)

    2015-08-01

    Ten researches that may represent the progress in Chinese oculoplastic surgery and orbital disease were selected through voting by specialists from Chinese Society of Ophthalmic Plastics and Orbital Disease. These researches focused on the following fields: the endoscopic navigation system of orbital surgery, orbital bone regeneration and materials, comprehensive sequence treatment of retinoblastoma, the mechanism of thyroid related ophthalmopathy, the intervention strategy and evaluation of orbital development with congenital microphthalmia and anophthalmia, blepharophimosis genotype-phenotype relationship and intervention strategies and clinical study of new materials for frontal muscle suspension. These studies represented the level and influence of Chinese oculoplastics and orbital disease in the international academic community and they were the landmark studies in our areas of expertise.

  9. Ten years of high temperature materials research at PSI - An overview paper

    International Nuclear Information System (INIS)

    Pouchon, Manuel A.; Chen Jiachao

    2014-01-01

    At the Paul Scherrer Institute high temperature materials research for advanced nuclear systems is performed since a decade, formerly by the HT-Mat group and today the advanced nuclear materials (ANM) group. In this paper the activities being conducted in this time are summarized. This includes the study of three major materials classes, intermetallics with a titanium alluminide, nanostructured steel with different ODS candidates, and ceramics with silicon carbide composites. The studies being performed include experimental work, studying the mechanical behavior as function of irradiation exposure and temperature, including also in situ studies such as the creep under ion beam irradiation plus miniaturized samples such as pillars. The microstructure changes as function of these exposures, using electron microscopy on one hand and advanced beamline techniques on the other hand. Part of the finding lead to the development of new damage mechanism models. Complementary to the experimental approach, modelling activities were conducted to understand the basics of the damage mechanisms. The research lead to a consolidation of the candidate materials to the most promising ones, namely the oxide dispersion strengthened steels (ODS) and the silicon carbide based composite materials. The research lead to new, relevant data such as the creep behavior of material under extreme reactor conditions, the embitterment mechanism in advanced materials, and much more. A sketch of the research philosophy and an outline of the main results will be given. (author)

  10. Effectiveness of different methods to control legionella in the water supply: ten-year experience in an Italian university hospital.

    Science.gov (United States)

    Marchesi, I; Marchegiano, P; Bargellini, A; Cencetti, S; Frezza, G; Miselli, M; Borella, P

    2011-01-01

    We report our ten-year experience of hyperchlorination, thermal shock, chlorine dioxide, monochloramine, boilers and point-of-use filters for controlling legionella contamination in a hospital hot water distribution system. Shock disinfections were associated with a return to pre-treatment contamination levels within one or two months. We found that chlorine dioxide successfully maintained levels at contamination was observed applying point-of-use filters and electric boilers at temperatures of >58°C and no cases of nosocomial legionellosis were detected in the ten-year observation period. Our performance ranking in reducing legionella contamination was filter, boiler, chlorine dioxide, hyperchlorination and thermal shock. Chlorine dioxide was the least expensive procedure followed by thermal shock, hyperchlorination, boiler and filter. We suggest adopting chlorine dioxide and electric boilers in parallel. Copyright © 2010 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved.

  11. Duration of Sexual Harassment and Generalized Harassment in the Workplace Over Ten Years: Effects on Deleterious Drinking Outcomes

    OpenAIRE

    McGinley, Meredith; Richman, Judith A.; Rospenda, Kathleen M.

    2011-01-01

    While harassment in the workplace has been linked to deleterious drinking outcomes, researchers have yet to examine the long-term effects of chronic workplace harassment. During a ten year longitudinal mail survey, university employees (N = 2265) were administered measures of sexual harassment, generalized workplace harassment, and problematic drinking. Using growth mixture modeling, two latent classes of workplace harassment emerged: infrequent and chronic. Demographic characteristics (gende...

  12. THE CURRENT SPREAD OF INVASIVE NEOPHYTES OF GENUS FALLOPIA IN TOWN HLOHOVEC (SW SLOVAKIA AFTER TEN YEARS

    Directory of Open Access Journals (Sweden)

    žaneta PAUKOV

    2013-03-01

    Full Text Available In this paper, we compare the current spread of invasive populations of neophytes, the genus Fallopia (Polygonaceae in town Hlohovec (SW Slovakia in intensively farmed agricultural landscape after ten years. F. bohemica has been the most successfully spreading hybrid. In 2001, it had colonized the area of 1 520 m2 on 54 localities and in 2011 by 120 % more (3 338 m2, 63 localities. The total surface area occupied by F. japonica was small.

  13. Ten years of invasion: Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae) in Britain

    Science.gov (United States)

    Roy, Helen E; Brown, Peter M J

    2015-01-01

    1. Harmonia axyridis was first recorded in Britain in 2004. Two subsequent earlier records were received from 2003. 2. The UK Ladybird Survey, a citizen science initiative involving online recording, was launched in 2005 to encourage people across Britain to track the spread of H. axyridis. Tens of thousands of people have provided records of H. axyridis and other species of ladybirds, creating an invaluable dataset for large-scale and long-term research. Declines in the distribution of seven (of eight assessed) native species of ladybird have been demonstrated, and correlated with the arrival of H. axyridis, using the records collated through the UK Ladybird Survey. 3. Experimental research and field surveys have also contributed to our understanding of the ecology of H. axyridis and particularly the process of invasion. Harmonia axyridis arrived in Britain through dispersal and introduction events from regions in which it was deliberately released as a biological control agent. The rapid spread of this species has been attributed to its high natural dispersal capability by means of both flight and anthropogenic transport. A number of factors have contributed to the successful establishment and indeed dominance of this polymorphic species within aphidophagous guilds, including high reproductive capacity, intra-guild predation, eurytopic nature, high resistance to natural enemies within the invaded range, and potentially phenotypic plasticity. 4. The global invasion by H. axyridis and subsequent research on this species has contributed to the general understanding of biological invasions. PMID:26435571

  14. Ten years' of experience in patient education of families with a child/adolescent suffering from cystic fibrosis

    DEFF Research Database (Denmark)

    Bregnballe, Vibeke

    2007-01-01

    of six lessons of 3−4 hours every second month in one year. For the 5-year-olds it is three lessons of three hours in three successive months. For the parents with newly diagnosed children we have meetings three times a year. The CF school is rooted in practice and experiences. Two books have been made......Aims: The patient education programme for families with children or adolescents with cystic fibrosis (the CF school) was established ten years ago to enable patients to make choices in their lives as CF patients. The CF school provides patients with knowledge about cystic fibrosis (CF), teaches...... them how to cope with the disease and how to take responsibility for the treatment. Methods: The CF school has developed during the last ten years. Now we have a CF school for 5-, 10- and 14-year-olds and annual meetings for each group in between. The CF school for the 10- and 14-year-olds consists...

  15. Tracheostomy in children: a ten-year experience from a tertiary center in southern Brazil,

    OpenAIRE

    Schweiger, Cláudia; Manica, Denise; Becker, Carolina Fischer; Abreu, Larissa Santos Perez; Manzini, Michelle; Sekine, Leo; Kuhl, Gabriel

    2017-01-01

    Abstract Introduction: Children may require tracheostomy due to many different health conditions. Over the last 40 years, indications of tracheostomy have endorsed substantial modifications. Objective: To evaluate pediatric patients warranted tracheostomy at our Hospital, in regard to their indications, associated comorbidities, complications and decannulation rates. Methods: Retrospective study concerning patients under 18 years of age undergoing tracheostomy in a tertiary health care cen...

  16. A ten year histopathological review of breast lumps in a tertiary ...

    African Journals Online (AJOL)

    37%) followed by fibrocystic change disease which accounted for 238 (24.5%). Fibroadenoma had a mean age of 22.3 (SD = 5.5) years. This was followed closely by invasive ductal carcinoma with a mean age of 48.2 (SD = 4.1) years.

  17. Ten-Year Trends in Public Opinion from the "EDNEXT" Poll

    Science.gov (United States)

    Peterson, Paul E.; Henderson, Michael B.; West, Martin R.; Barrows, Samuel

    2017-01-01

    The year 2016 marks the 10th anniversary of the "Education Next" poll on K-12 education policy, offering "Education Next" the opportunity to take a retrospective look at public opinion on this vital topic. In 8 of the past 10 years, "Education Next" has also surveyed teachers on the subject and has seen some…

  18. Ten years of Nature Reviews Neuroscience: insights from the highly cited

    NARCIS (Netherlands)

    Luo, L.; Rodriguez, E.; Jerbi, K.; Lachaux, J.P.; Martinerie, J.; Corbetta, M.; Shulman, G.L.; Piomelli, D.; Turrigiano, G.G.; Nelson, S.B.; Joëls, M.; de Kloet, E.R.; Holsboer, F.; Amodio, D.M.; Frith, C.D.; Block, M.L.; Zecca, L.; Hong, J.S.; Dantzer, R.; Kelley, K.W.; Craig, A.D.

    2010-01-01

    To celebrate the first 10 years of Nature Reviews Neuroscience, we invited the authors of the most cited article of each year to look back on the state of their field of research at the time of publication and the impact their article has had, and to discuss the questions that might be answered in

  19. Giant vesical calculus in a ten year-old boy - a case report | Saleh ...

    African Journals Online (AJOL)

    This is a case of longstanding urinary tract symptoms in a 10 year old boy in which multi-modality imaging revealed multiple radio-opaque calculi including a giant vesical calculus. He had surgical removal of the stone with no post-op complications. Keywords: Giant, Vesical Calculus, 10 years old ...

  20. Ten-year literature review of global endometrial ablation with the NovaSure® device

    Directory of Open Access Journals (Sweden)

    Gimpelson RJ

    2014-03-01

    Full Text Available Richard J Gimpelson Mercy Clinic, Minimally Invasive Gynecology, Department of Obstetrics and Gynecology, Mercy Hospital St Louis, St Louis, MO, USA Abstract: This review examines the peer-reviewed literature describing prospective studies that report amenorrhea rates, patient satisfaction, and surgical reintervention rates following the NovaSure® endometrial ablation procedure. A search of the English-language literature published from 2000 to 2011 was conducted using PubMed. Ten prospective studies, six single-arm NovaSure trials, and four randomized controlled trials comparing the NovaSure procedure with other global endometrial ablation modalities met the inclusion criteria and were reviewed. The follow-up periods ranged from 6 to 60 months. Amenorrhea rates for the NovaSure procedure ranged from 30.0% to 75.0%. Patients who reported being satisfied with the NovaSure procedure ranged from 85.0% to 94.0%. In randomized controlled trials with other global endometrial ablation modalities, amenorrhea rates at 12 months with the NovaSure procedure ranged from 43.0% to 56.0%, while other modalities ranged from 8% to 24%. In addition, this manuscript reviews the following: the NovaSure technology; use of the NovaSure procedure in the office setting; intraoperative and postoperative pain; effects on premenstrual syndrome (PMS; dysmenorrhea; special circumstances, including presence of uterine disease, history of cesarean delivery, coagulopathy, or use of anticoagulant medication; post-procedure uterine cavity assessment and cancer risk; contraception and pregnancy; and safety. Keywords: abnormal uterine bleeding, menorrhagia, endometrial ablation, NovaSure®

  1. Ten years of democracy: Translating policy into practice in mathematics and science education

    Directory of Open Access Journals (Sweden)

    Kgabo Masehela

    2005-10-01

    Full Text Available This paper provides a 10-year (1994 – 2004 review of the state of mathematics and physical science education (SME in South Africa with respect to participation and performance, and its relationship with policy implementation.

  2. Meeting Report: Minutes from EMBO: Ten Years of Comparative Genomics of Eukaryotic Microorganisms

    Czech Academy of Sciences Publication Activity Database

    Lukeš, Julius; López-García, P.; Louis, E.; Boekhout, T.

    2016-01-01

    Roč. 167, č. 3 (2016), s. 217-221 ISSN 1434-4610 Institutional support: RVO:60077344 Keywords : protist * eukaryotic microorganisms * genomics Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 2.794, year: 2016

  3. The ten-thousand year fever: rethinking human and wild primate malarias

    National Research Council Canada - National Science Library

    Cormier, Loretta A

    2011-01-01

    "Malaria is one of the oldest recorded diseases in human history, and its 10,000-year relationship to primates can teach us why it will be one of the most serious threats to humanity in the 21st century...

  4. Determination of the levels of trace elements in ten years old children from Antofagasta city, Chile by neutron activation analysis

    International Nuclear Information System (INIS)

    Gras, N.; Munoz, A.L.; Jamett J, A.; Pena C, L.; Santander M, M.

    1988-01-01

    The levels of trace elements in scalp hair of ten years old children of Antofagasta city were determined. For this study, the city was divided in convenient areas. Comparisons between levels of concentrations considering residential areas, sex, values obtained for children of Santiago, and the ranges given in the literature were established. Fifty samples of hair were analyzed by instrumental neutron activation analisis. The elements selected were: As, Br, Co, Cr, Cu, Fe, Hg, K, Na. Sb, and Zn. The effectiveness of wash procedure before irradiation was studied. Ten samples were taken with sufficient amount of hair and each was divided into two, only one of them was washed and both were analyzed. The levels of concentrations were compared. (author)

  5. Ten Years of Forest Cover Change in the Sierra Nevada Detected Using Landsat Satellite Image Analysis

    Science.gov (United States)

    Potter, Christopher S.

    2014-01-01

    A detailed geographic record of recent vegetation regrowth and disturbance patterns in forests of the Sierra Nevada remains a gap that can be filled with remote sensing data. Landsat (TM) imagery was analyzed to detect 10 years of recent changes (between 2000 and 2009) in forest vegetation cover for areas burned by wildfires between years of 1995 to 1999 in the region. Results confirmed the prevalence of regrowing forest vegetation during the period 2000 and 2009 over 17% of the combined burned areas.

  6. Ten years' experience using an integrated workers' compensation management system to control workers' compensation costs.

    Science.gov (United States)

    Bernacki, Edward J; Tsai, Shan P

    2003-05-01

    This work presents 10 years of experience using an Integrated Workers' Compensation Claims Management System that allows safety professionals, adjusters, and selected medical and nursing providers to collaborate in a process of preventing accidents and expeditiously assessing, treating, and returning individuals to productive work. The hallmarks of the program involve patient advocacy and customer service, steerage of injured employees to a small network of physicians, close follow-up, and the continuous dialogue between parties regarding claims management. The integrated claims management system was instituted in fiscal year 1992 servicing a population of approximately 21,000 individuals. The system was periodically refined and by the 2002 fiscal year, 39,000 individuals were managed under this paradigm. The frequency of lost-time and medical claims rate decreased 73% (from 22 per 1000 employees to 6) and 61% (from 155 per 1000 employees to 61), respectively, between fiscal year 1992 and fiscal year 2002. The number of temporary/total days paid per 100 insureds decreased from 163 in fiscal year 1992 to 37 in fiscal year 2002, or 77%. Total workers' compensation expenses including all medical, indemnity and administrative, decreased from $0.81 per $100 of payroll in fiscal year 1992 to $0.37 per $100 of payroll in fiscal year 2002, a 54% decrease. More specifically, medical costs per $100 of payroll decreased 44% (from $0.27 to $0.15), temporary/total, 61% (from $0.18 to $0.07), permanent/partial, 63% (from $0.19 to $0.07) and administrative costs, 48% ($0.16 to $0.09). These data suggests that workers' compensation costs can be reduced over a multi-year period by using a small network of clinically skilled health care providers who address an individual workers' psychological, as well as physical needs and where communication between all parties (e.g., medical care providers, supervisors, and injured employees) is constantly maintained. Furthermore, these results

  7. Radiochemistry - today

    International Nuclear Information System (INIS)

    After a longer starting period many radiation techniques have prevailed practically. Today radiation processes are usual components of chemistry, biology, medicine, and technologies in the most common sense. This paper deals with the latest state of radiation chemistry, whereas the possible practical applications are in the foreground of discussion as to reach mainly practicians in laboratory and industry. But also physicians, pharmacists and chemical engineers should be informed about the possibilities of application of high energyy radiation. Because radiation chemistry has also enriched works of related subjects, for example physical, organic and inorganic chemistry, this paper will also be of interest for experts of these disciplines. (orig.) [de

  8. Ten years of Nature Reviews Neuroscience: insights from the highly cited.

    Science.gov (United States)

    Luo, Liqun; Rodriguez, Eugenio; Jerbi, Karim; Lachaux, Jean-Philippe; Martinerie, Jacques; Corbetta, Maurizio; Shulman, Gordon L; Piomelli, Daniele; Turrigiano, Gina G; Nelson, Sacha B; Joëls, Marian; de Kloet, E Ronald; Holsboer, Florian; Amodio, David M; Frith, Chris D; Block, Michelle L; Zecca, Luigi; Hong, Jau-Shyong; Dantzer, Robert; Kelley, Keith W; Craig, A D

    2010-10-01

    To celebrate the first 10 years of Nature Reviews Neuroscience, we invited the authors of the most cited article of each year to look back on the state of their field of research at the time of publication and the impact their article has had, and to discuss the questions that might be answered in the next 10 years. This selection of highly cited articles provides interesting snapshots of the progress that has been made in diverse areas of neuroscience. They show the enormous influence of neuroimaging techniques and highlight concepts that have generated substantial interest in the past decade, such as neuroimmunology, social neuroscience and the 'network approach' to brain function. These advancements will pave the way for further exciting discoveries that lie ahead.

  9. Ten years research activities in Earth observation at the Cyprus University of Technology

    Science.gov (United States)

    Hadjimitsis, Diofantos G.; Themistocleous, Kyriacos; Agapiou, Athos; Mamouri, Rodanthi; Nisantzi, Argyro; Papoutsa, Christiana; Tzouvaras, Marios; Neoclous, Kyriacos; Mettas, Christodoulos; Michaelides, Silas

    2017-09-01

    This paper presents the achievements for the last 10 years of the Remote Sensing and Geo-Environment Laboratory of the Cyprus University of Technology in the Earth observation through the ERATOSTHENES Research Centre. Over the past 10 years, the Centre has secured competitive research funding from various sources, such as the European Commission, the Cyprus Research Promotion Foundation, as well as industrial partners, having participated either as a coordinator or as a partner in more than 60 research projects. The research activities of the Centre encompass remote sensing and GIS applications in the fields of Cultural Heritage, Agriculture, Water Resource Management, Environment, Infrastructure, Marine Spatial Planning, Atmospheric, Air Pollution and Coastal Applications, Natural Resource Management and Hazard Assessment. The aim of this paper is to map the existing activities and identify the future trends and goals of the Eratosthenes Research Centre for the next 15 years.

  10. Ten years of vegetation assembly after a North American mega fire.

    Science.gov (United States)

    Abella, Scott R; Fornwalt, Paula J

    2015-02-01

    Altered fuels and climate change are transforming fire regimes in many of Earth's biomes. Postfire reassembly of vegetation--paramount to C storage and biodiversity conservation--frequently remains unpredictable and complicated by rapid global change. Using a unique data set of pre and long-term postfire data, combined with long-term data from nearby unburned areas, we examined 10 years of understory vegetation assembly after the 2002 Hayman Fire. This fire was the largest wildfire in recorded history in Colorado, USA. Resistance (initial postfire deviance from prefire condition) and resilience (return to prefire condition) declined with increasing fire severity. However, via both resistance and resilience, 'legacy' species of the prefire community constituted >75% of total plant cover within 3 years even in severely burned areas. Perseverance of legacy species, coupled with new colonizers, created a persistent increase in community species richness and cover over prefire levels. This was driven by a first-year increase (maintained over time) in forbs with short life spans; a 2-3-year delayed surge in long-lived forbs; and a consistent increase in graminoids through the 10th postfire year. Burning increased exotic plant invasion relative to prefire and unburned areas, but burned communities always were >89% native. This study informs debate in the literature regarding whether these increasingly large fires are 'ecological catastrophes.' Landscape-scale severe burning was catastrophic from a tree overstory perspective, but from an understory perspective, burning promoted rich and productive native understories, despite the entire 10-year postfire period receiving below-average precipitation. Published 2014. This article is a U.S. Government work and is in the public domain in the USA.

  11. Ten-year absolute risk of osteoporotic fractures according to BMD T score at menopause

    DEFF Research Database (Denmark)

    Abrahamsen, Bo; Vestergaard, Peter; Rud, Bo

    2006-01-01

    was 10.9% as opposed to an expected risk of 5.7%. Relative risk gradients were similar to those of the recent meta-analysis. CONCLUSIONS: In healthy women, examined in the first year or two after menopause, 10-year fracture risk was higher at each level of BMD T score than expected from the model...... by Kanis et al. Inclusion of HRT users in the cohorts used may have led to higher BMD values and lower absolute fracture risk in the Kanis model. These longitudinal data can be used directly in estimating absolute fracture risk in untreated north European women from BMD at menopause....

  12. Radiation environmental monitoring and assessment of plant-221 site ten years after decommissioning

    International Nuclear Information System (INIS)

    Li Yang; Gu Zhijie; Pan Wei; Ren Xiaona; Hu Xiaolin; She Haiqiang

    2011-01-01

    More than 10 years have passed since nuclear facility decommissioning practice for Plant-221 finished. Environmental radiation monitoring and post assessment of the decommissioning site of Plant-221 was carried out during 2003-2006, which was organized by Department of Environmental Protection and executed by China Institute for Radiation Protection, Environmental Radiation Monitoring station of Qinghai Province, etc. It shows that the decommissioning practice for Plant-221 complied with relevant limits for decommissioning, and its environmental radiation situation has not had significant change in general after 10 years, and the potential impact to the public and the environmental is acceptable. (authors)

  13. Ten years investigation on radiological exposures to the embryo and fetus in pregnant women of Iran

    International Nuclear Information System (INIS)

    Arbabi, A.

    2001-01-01

    Over 1340 Iranian pregnant patients, exposed to diagnostic x-rays during 1984 to 1994, referred to me for investigation and estimation of the absorbed dose to their embryo or fetus. They were almost all the patients exposed to x-rays in the whole country in 10 years. Two sets of questionnaires were filed for each patient and all the exposing condition and setting information obtained from the radiology centers concerned. The absorbed dose to embryo or fetus accurately calculated and in some cases measured in a phantom for each patient. The youngest patient at the time of irradiation was 15 and the oldest was 51 with an average of 28.624±5.961 years old. The AP and lateral thickness of patient's abdomen on average were 18.078±0.162 cm and 24.630±8.365 cm respectively. The average weight of patients was 59.285±12.945 kg. ranging from 30 kg to 122 kg. The marriage age of the patients on average was 19.398±4.107 years ranging from 9 to 42 years old. The average age of fetus when exposed to x-rays was 31.22±18.76 days. About 20% of the patients had exposures in 2 to 4 more sessions. The average fetal dose was 0.68±0.381 cGy with over 37% from 1 to 9 cGy. (author)

  14. The Northern hardwood forest ecosystem: ten years of recovery from clearcutting

    Science.gov (United States)

    J.W. Hornbeck; C.W. Martin; R.S. Pierce; F.H. Bormann; G.E. Likens; J.S. Eaton; J.S. Eaton

    1987-01-01

    Two even-age management systems, progressive strip cutting and block clearcutting, have been studied since 1970 on small watersheds at the Hubbard Brook Experimental Forest, New Hampshire. In the strip cutting, all merchantable trees were harvested in a series of three strips over 4 years (1970-74). In the block clearcutting, all trees were harvested in a single...

  15. A Content Analysis of LGBTQ Qualitative Research in Counseling: A Ten-Year Review

    Science.gov (United States)

    Singh, Anneliese A.; Shelton, Kimber

    2011-01-01

    This content analysis examines the qualitative methodology used in counseling research with lesbian, gay, bisexual, transgender, and queer (LGBTQ) issues published over the last 10 years (1998-2008) in 4 counseling and counseling psychology journals ("Journal of Counseling & Development," "Journal of Counseling Psychology," "Journal of LGBT Issues…

  16. Alternatives to Custody: A Ten-Year Review of a Community-Based Program in Britain.

    Science.gov (United States)

    Stevens, Barbara Christine

    1996-01-01

    Describes the development of a community forensic psychology service during its first 10 years of service. Service emphasizes cooperation among psychologists, probation officers, and others in establishing alternatives to custody for sex offenders, shoplifters, drug and alcohol abusers, and young criminals. Discusses theoretical orientation of the…

  17. A Ten-Year Chronicle of Student Attitudes toward Foreign Language in the Elementary School

    Science.gov (United States)

    Heining-Boynton, Audrey L.; Haitema, Thomas

    2007-01-01

    This article reports the results of 2 studies conducted over a 10-year period that researched student attitudes toward early foreign language learning. These studies are unique because of the long time frame in which the students were followed, and the large data sets collected at the elementary school level. Surveys of students in the Foreign…

  18. Graft Fibrosis After Pediatric Liver Transplantation : Ten Years of Follow-up

    NARCIS (Netherlands)

    Scheenstra, Rene; Peeters, Paul M. G. J.; Verkade, Henkjan J.; Gouw, Annette S. H.

    Previously we reported the presence of portal fibrosis in 31% (n = 84) of the grafts in protocol biopsies I year after pediatric liver transplantation (LTx). To assess the natural history of graft fibrosis after pediatric liver transplantation, we extended the analysis of graft histology in

  19. Ten Year Assessment of Learning Outcomes of a Computer Information Systems (CIS) Program

    Science.gov (United States)

    Abraham, Samuel

    2013-01-01

    In recent years greater attention has been paid to develop learning outcomes for academic programs and then to develop methods to assess these learning outcomes. Generally speaking, there are two kinds of outcomes: course outcomes and program outcomes. Assessments of these learning outcomes in institutions of higher education are mandated by the…

  20. Mastered horror. Life in the Ukraine ten years after the Chernobyl accident

    International Nuclear Information System (INIS)

    Boos, S.

    1996-01-01

    The book, written in a journalistic style, reports on the visit of the author on her visit to the Ukraine 10 years after the Chernobyl accident. It is based on interviews with the affected population, with scientists (doctors, veterinarians, biologists, psychologists, ecologists), parliamentarians and representatives of the state administration. figs., refs

  1. Achieving Collective Impact: Reflections on Ten Years of the University of Georgia Archway Partnership

    Science.gov (United States)

    Garber, Mel; Adams, Katherine R.

    2017-01-01

    Collective impact is a model for achieving tangible change and improvement in communities through a series of well-defined parameters of collaboration. This article provides a 10-year reflection on the University of Georgia Archway Partnership, a university-community collaboration, in the context of the parameters of collective impact. Emphasis is…

  2. Diseases Of Poultry In Zaria, Nigeria: A Ten Year Analysis Of Clinic ...

    African Journals Online (AJOL)

    A to~year study of poultry diseases diagnosed at the Avian clinic of Veterinary Teaching Hospital, Ahmadu Bello University, Zaria was conducted. In all 2999 cases were studied. The commonest diseases afflicting poultry were Newcastle disease, 31.2%, Gumboro 12.0%, Ectoparasitism 7.7%, Fowl pox 6.8%, Helminthiasis ...

  3. The Fundacion Universidad Empresa of Madrid, Ten Years of Experience in University-Industry Relations.

    Science.gov (United States)

    Saenz de Miera, Antonio

    1983-01-01

    The first 10 years of Spain's leading organization designed to promote the establishment of relationships between universities and industry are discussed. Its activities in scientific and technical research projects and funding, continuing education programs, and coordination of employment opportunities are outlined. (MSE)

  4. Ten-year observation of peptic ulceration at Ga-Rankuwa Hospital ...

    African Journals Online (AJOL)

    For the 10-year period 1979-1988, the incidence of endoscopically diagnosed peptic ulceration at Ga-Rankuwa Hospital was studied with particular reference to: type of ulcer; age, sex and place of residence of the patients; and patient's occupations. The incidence of peptic ulceration remained unchanged. In this area ...

  5. Colorectal cancer in Mauritius: facts and figures -‐ A ten year ...

    African Journals Online (AJOL)

    Among the various types of cancers in Mauritius, colorectal cancer has evolved as 1st in male and 3rd in female in 2008 (National Cancer Action Plan 2010 MOH & QL, Mauritius). Colorectal cancer is one of the leading causes of death worldwide. A retrospective study of 10 years (2001-‐2010) has been carried out using ...

  6. A ten-year study of prostate cancer specimens at Ahmadu Bello ...

    African Journals Online (AJOL)

    Objective: To analyze the pattern of distribution of prostate cancer among men in Zaria, Northern Nigeria. Patients and methods: This is a 10-year retrospective histopathological analysis of all prostate cancer cases diagnosed between January 1991 and December 2000 in the Department of Pathology, Ahmadu Bello ...

  7. Ten-year clinical assessment of three posterior resin composites and two amalgams.

    Science.gov (United States)

    Mair, L H

    1998-08-01

    The long-term clinical performance of three posterior resin composites and two amalgams was assessed. Thirty Class II restorations each of P-30, Occlusin, Clearfil Posterior (composites), New True Dentalloy, and Solila Nova (amalgams) were placed. Reviews took place at 6 months and at 1, 2, 3, 4, 5, and 10 years. At each visit the gingival condition, the contact point status, and the presence of ledges, gaps, or recurrent caries were assessed. The color match, cavosurface marginal stain, general surface stain, tarnish, and corrosion were also scored where applicable. Epoxy resin replicas were used to measure the maximum depth of wear. After 10 years, there had been corrosion of both the high- and low-copper amalgams and a slight deterioration in color match of a number of composite restorations. Eighteen (of 20) Occlusin restorations had obvious cavosurface marginal stain, attributed to staining of the unfilled bonding resin layer. Statistical analysis indicated that New True Dentalloy, Solila Nova, and Clearfil-P exhibited significantly less wear than Occlusin and P-30. None of the restorations examined at the 10-year recall required replacement. The five materials, placed in a dental school environment, provided adequate clinical service for 10 years.

  8. Ten years after the introduction of Aldrovanda vesiculosa to the Czech Republic

    Czech Academy of Sciences Publication Activity Database

    Adamec, Lubomír

    2005-01-01

    Roč. 152, č. 2 (2005), s. 239-245 ISSN 1253-8078. [5th Conference of International Carnivorous Plant Society. Lyon, 17.06.2004-21.06.2004] Institutional research plan: CEZ:AV0Z6005908 Keywords : aquatic carnivorous plant, * Třeboňsko Area * dystrophic waters Subject RIV: EF - Botanics Impact factor: 0.224, year: 2005

  9. A ten-year study of measles admissions in a Nigerian Teaching ...

    African Journals Online (AJOL)

    Background: Measles remains a major cause of childhood morbidity and mortality in Nigeria despite the availability of safe and effective vaccines. The last report on measles from our center was about 15 years ago. A review of the current status is necessary in order to strengthen interventional strategies. Objectives: To ...

  10. [A ten-year clinical study of cracked teeth restored with glass ceramic crowns].

    Science.gov (United States)

    Luo, X P; Yuan, Y; Shi, Y J; Qian, D D

    2016-10-09

    Objective: To evaluate the clinic performance of high strength glass ceramic crowns for the painful cracked teeth during a 10-year observation period. Methods: Forty-two posterior teeth from 36 patients were diagnosed as having a crack, biting painful and sensitivity to cold were selected in the Department of Prosthodontic, Institute and Hospital of Stomatology, Nanjing University Medical School. The lost-wax hot pressed glass ceramic crowns were bonded on the minimally invasive prepared teeth by modern adhesive technology. Patients were interviewed and went through clinic examination after one week, one month, and every six months. Results: The effectiveness of 42 glass ceramic crowns for cracked teeth was evaluated for a mean observation time over 10-year. At the first week, 29(81%) patients were free of pain, three still had sensitivity to cold and chewing pain, three still had sensitivity to cold, one had painful to cold and hot. After one month, two patients still had chewing pain, and one tooth needed endodontic treatment after six months. In 10 years, 2(5%) all ceramic crowns were broken, the other 40 restorations kept good clinical performances with a 10-year survival rate of 95%. Conclusions: The high strength glass ceramic crowns are very effective and successful in treating the cracked teeth and then keep the good mastication function and appearance.

  11. Ten- to sixteen-year-olds' perceptions of advertisements for alcoholic drinks.

    Science.gov (United States)

    Aitken, P P; Leathar, D S; Scott, A C

    1988-01-01

    Groups of children discussed a number of issues concerning advertising, including advertisements they liked and disliked. The findings suggest that advertisements for alcoholic drinks become increasingly salient and attractive over the years 10 to 14. For example, although 10-year-olds rarely mentioned advertisements for alcoholic drinks when talking about favourite television commercials, the older children tended to do so almost immediately. There were also consistent developmental trends in their descriptions of liked and disliked qualities of advertisements and of the symbolism in commercials for alcoholic drinks. Whereas the 10-year-olds' comments tended to be tied to what is specifically shown in commercials, the older children tended to go beyond this and alluded to much more complex imagery, much in the same way that adults do. For example, the 14- and 16-year-olds tended to see larger and beer commercials as promoting masculinity, sociability and working-class values. These findings indicate that advertising campaigns for alcoholic drinks aimed at older teenagers and young adults present qualities which younger teenagers find attractive. We suggest it is no longer tenable for advertisers to absolve themselves of any responsibility by saying that advertisements for alcoholic drinks are targeted only at adults.

  12. Ten-year cumulative incidence of diabetic retinopathy. The Beijing Eye Study 2001/2011.

    Directory of Open Access Journals (Sweden)

    Jie Xu

    Full Text Available To assess the cumulative 10-year incidence of diabetic retinopathy (DR and its associated factors in a population living in Greater Beijing.The population-based longitudinal Beijing Eye Study, which included 4439 subjects (age in 2001: 40+years in 2001, was repeated in 2011 with 2695 subjects participating (66.4% of the survivors. The study participants underwent a detailed ophthalmic examination. Fundus photographs were examined for the new development of DR.After excluding individuals with DR at baseline (n = 87 or no sufficient fundus photographs in 2011 (n = 6, the study included 2602 subjects with a mean age of 64.6±9.7 years (median: 64.0 years; range: 50 to 93 years. In the 10-year period, 109 subjects (39 men developed new DR with an incidence of 4.2% (95% confidence interval (CI: 3.45,5.03. In multiple logistic regression analysis, incident DR was significantly associated with higher HbA1c value (P<0.001; Odds Ratio (OR: 1.73; 95% Confidence Interval (CI: 1.35,2.21, longer duration of diabetes mellitus (P<0.001; OR: 1.16; 95% CI: 1.10,1.22, higher serum concentration of creatinine (P = 0.02; OR: 1.01; 95% CI: 1.002,1.022, lower educational level (P = 0.049; OR: 0.74; 95% CI: 0.55,0.99, higher estimated cerebrospinal fluid pressure (P = 0.038; OR: 1.10; 95% CI: 1.01,1.22, and shorter axial length (P<0.001; OR: 0.48; 95% CI: 0.33,0.71.The cumulative 10-year incidence (mean: 4.2% of DR in a North Chinese population was significantly associated with a higher HbA1c value, longer known duration of diabetes mellitus, higher estimated CSFP and shorter axial length (P<0.001. Shorter axial length (or hyperopia and, potentially, higher CSFP may be additional risk factors to be taken into account when counseling and treating patients with diabetes mellitus.

  13. Veterinary parasitology teaching - Ten years of experience with the Vetsuisse curriculum.

    Science.gov (United States)

    Schnyder, Manuela; Hertzberg, Hubertus; Mathis, Alexander; Schönmann, Marietta; Hehl, Adrian; Deplazes, Peter

    2018-03-15

    Pursuant to the Joint Declaration by 29 European education ministers in June 1999 in the city of Bologna, Italy, the so-called 'Bologna Process' was officially introduced at the Vetsuisse Faculty (Universities of Zurich and Berne) in Switzerland in 2007. The long-term goal of restructuring the study programmes was to create a common European Higher Education Area (EHEA), with uniform and clearly defined standards for degrees ("diplomas"). Accordingly, the Vetsuisse curriculum was organised as a 3-year Bachelor and a 2-year Master study program. For the final Federal examination in veterinary medicine, both programs and a master thesis have to be completed. Parasitology, as a subject, is introduced with selected examples in the ecology course during the first academic year. The second and third years of the Bachelor program comprise non-organ-centred (NOC) and integrated organ-centred (OC) course modules, respectively. In the NOC modules, parasitology is taught in consecutive courses, focussing on topics including occurrence, biology, pathogenesis, clinical manifestations, diagnostics and the strategic principles of therapeutic and prophylactic interventions against major veterinary and zoonotic parasites. This syllabus is complemented with live demonstrations as well as practical laboratory exercises. Lecture notes, with defined learning objectives, are based on the textbook "Parasitology in Veterinary Medicine" which is available free of charge to students as an on-line edition in German. Furthermore, students review relevant parasitoses in the diagnostic context of OC case presentations. In another module, immunological aspects of parasitic diseases are elaborated on group sessions, supported through the use of specialist literature. The two-year Master program is divided into a core syllabus for all students, and elective subjects are chosen from six areas of specialisation (three each with clinical or non-clinical focus). Within the clinically focused

  14. Pulmonary function after lobectomy in children under ten years of age

    International Nuclear Information System (INIS)

    Nonoyama, Akira; Tanaka, Kazuho; Kagawa, Kiyoshi

    1985-01-01

    Children's ages at the time of the operation ranged from 1 to 4 years in 6 patients and 5 to 10 years in other 6 cases. Their resected lobes were 2 right upper lobes, 1 right middle lobe, 5 right lower lobes, 2 left upper lobes and 2 left lower lobes. At the follow-up period of 4 months to 13 years after surgery, all of the patients were subjectively well with a physical performance equal to those of their peers, and in 11 of them, no apparent residual pulmonary disease was demonstrated. Nine of these 11 patients were over 7 years of age and their course after surgery were more than 6 months. In these nine patients, postoperative forced vital capacity increased over the predicted value calculated from the estimated amount of lung removed. In most of the patients, %VC was about 82% in the upper lobectomized cases and more than 90% in the lower lobectomized patients. Functional residual capacity and total lung capacity generally decreased in proportion to the amount of lung tissue removed. Vital capacity and total lung capacity in the lower lobectomized patients were significantly increased compared with those in the upper lobectomized patients. The ratio of residual volume to total lung capacity decreased in all cases and, conversely, VC/TLC increased over normal value. The ratio of forced expiratory volume in the first second to vital capacity was over 82%. Flow-volume curve and closing volume were within normal limits in all except 2 cases, in whom the follow-up period was about 6 months after surgery. In the other 2 patients, whose ages were under 7 years. Technetium 99m macroaggregated albumin perfusion scan on the operated side showed values corresponding to the estimated amount of removed lung or values higher than the predicted, and the results of radiospirometry coincided with the results of spirometric respiratory function data. (J.P.N.)

  15. [Intraosseous puncture in preclinical emergency medicine. Ten years experience in air rescue service].

    Science.gov (United States)

    Helm, M; Hauke, J; Bippus, N; Lampl, L

    2007-01-01

    The intraosseous puncture (IO) is a fast and safe alternative to the puncture of peripheral veins in emergency situations in children < or =6 years of age. The purpose of this paper is to summarize 10 years of experience on the prehospital use of the IO method by the Helicopter Emergency Medical Service (HEMS) "Christoph 22", Ulm. This was a retrospective study from 1 January 1996 to 31 December 2005. Out of a total of 9,549 missions, the proportion of children was 11.1%. In 27 children (4.2% of the children < or =6 years of age) an IO puncture was performed. Patients of the IO group were younger (1.0 vs. 3.7 years of age; p<0.001) and showed a higher degree of injury severity (NACA 6 vs. 4; p<0.001) compared to the total children group. In all children of the IO group (100%), the intraosseous puncture was the method of first choice to obtain access to the vascular system by the HEMS team. In 96.4% of these cases (26/27), the first IO puncture attempt was successful - in one child, a second puncture attempt was necessary. A standardized puncture technique was performed using the proximal tibia. The time required for successful placement of the IO infusion line was 60 s or less in all cases. In 37% of the cases (10/27) the IO infusion line was used for induction of general anaesthesia; dosage and onset of administered drugs were described as being equivalent to a peripheral infusion line. In all cases, the IO needle was replaced in-hospital within 2 h by a central or peripheral iv line. No complications were observed. The IO infusion technique is a simple, fast and safe alternative method for emergency access to the vascular system in children < or =6 years of age in the prehospital setting.

  16. Prediction of Parkinson's disease subsequent to severe depression: a ten-year follow-up study.

    Science.gov (United States)

    Walter, Uwe; Heilmann, Robert; Kaulitz, Lara; Just, Tino; Krause, Bernd Joachim; Benecke, Reiner; Höppner, Jacqueline

    2015-06-01

    Major depressive disorder (MDD) has been associated with an increased risk of subsequent Parkinson's disease (PD) in case-control and cohort studies. However, depression alone is unlikely to be a useful marker of prodromal PD due to its low specificity. In this longitudinal observational study, we assessed whether the presence of other potential markers of prodromal PD predicts the subsequent development of PD in MDD patients. Of 57 patients with severe MDD but no diagnosis of PD who underwent a structured interview, olfactory and motor investigation and transcranial sonography at baseline, 46 (36 women; mean age 54.9 ± 11.7 years) could be followed for up to 11 (median, 10) years. Three patients (2 women; age 64, 65 and 70 years) developed definite PD after 1, 7, and 9 years, respectively. The combined finding of mild asymmetric motor slowing, idiopathic hyposmia, and substantia nigra hyperechogenicity predicted subsequent PD in all patients who could be followed for longer than 1 year. Out of the whole study cohort, only the subjects with subsequent PD presented with the triad of asymmetric motor slowing, idiopathic hyposmia, and substantia nigra hyperechogenicity in combination with at least two out of four reportable risk factors (family history of PD, current non-smoker, non-coffee drinker, constipation) at baseline investigation. Post-hoc analysis revealed that additional rating of eye and eye-lid motor abnormalities might further improve the prediction of PD in larger cohorts. Findings of this pilot-study suggest that MDD patients at risk of subsequent PD can be identified using an inexpensive non-invasive diagnostic battery.

  17. Corneal Graft Rejection Ten Years after Penetrating Keratoplasty in the Cornea Donor Study

    Science.gov (United States)

    Dunn, Steven P.; Gal, Robin L.; Kollman, Craig; Raghinaru, Dan; Dontchev, Mariya; Blanton, Christopher L.; Holland, Edward J; Lass, Jonathan H.; Kenyon, Kenneth R.; Mannis, Mark J; Mian, Shahzad I.; Rapuano, Christopher J.; Stark, Walter J.; Beck, Roy W.

    2015-01-01

    Purpose To assess the effect of donor and recipient factors on corneal allograft rejection and evaluate whether a rejection event was associated with graft failure. Methods 1,090 subjects undergoing penetrating keratoplasty for a moderate risk condition (principally Fuchs’ dystrophy or pseudophakic corneal edema) were followed for up to 12 years. Associations of baseline recipient and donor factors with the occurrence of a rejection event were assessed in univariate and multivariate proportional hazards models. Results Among 651 eyes with a surviving graft at 5 years, the 10-year graft failure (± 99% CI) rates were 12% ± 4% among eyes with no rejection events in the first 5 years, 17% ± 12% in eyes with at least one probable, but no definite rejection event, and 22% ± 20% in eyes with at least one definite rejection event. The only baseline factor significantly associated with a higher risk of definite graft rejection was a preoperative history of glaucoma, particularly when prior glaucoma surgery had been performed and glaucoma medications were being used at time of transplant (10-year incidence 35% ± 23% compared with 14% ± 4% in eyes with no history of glaucoma/intraocular pressure treatment, p=0.008). Conclusion Those patients who experienced a definite rejection event frequently went on to graft failure raising important questions as to how we might change acute and long-term corneal graft management. Multivariate analysis indicated that the prior use of glaucoma medications and glaucoma filtering surgery was a significant risk factor related to a definite rejection event. PMID:25119961

  18. Ten-year outcomes of monomorphic ventricular tachycardia catheter ablation in repaired tetralogy of Fallot.

    Science.gov (United States)

    Laredo, Mikaël; Frank, Robert; Waintraub, Xavier; Gandjbakhch, Estelle; Iserin, Laurence; Hascoët, Sebastien; Himbert, Caroline; Gallais, Yves; Hidden-Lucet, Françoise; Duthoit, Guillaume

    2017-05-01

    Monomorphic ventricular tachycardia (MVT) is common in adults with repaired tetralogy of Fallot (TOF), and is associated with sudden cardiac death. Management of MVT is not defined, and results of catheter ablation (CA) are limited. To evaluate long-term outcomes of MVT CA in repaired TOF. Thirty-four patients (mean age 32±10.3 years; 59% male) with repaired TOF underwent CA for symptomatic MVT between 1990 and 2012 in our centre; direct-current ablation (DCA) was used in 6%, radiofrequency followed by DCA in 29% and radiofrequency alone in 65%. Right ventricular (RV) dysfunction was present in 35% and left ventricular (LV) dysfunction in 21%. Mean numbers of clinical and induced MVTs were 1 and 2, respectively. Mean VT rate was 225±95bpm. Ablation targeted a single site (range 1-2), which was RV outflow tract in 85%. Primary success, defined as ventricular tachycardia (VT) termination during CA and final non-inducibility, was obtained in 82%. Seven patients (21%) required redo ablation in the first 3 months (before 2004; DCA). No death related to CA occurred. Mean follow-up time was 9.5±5.2 years. Antiarrhythmic therapy was discontinued in 71%. There were two cases of sudden cardiac death and four VT recurrences. Freedom from death and arrhythmia recurrence was 94% at 5 years, 81% at 10 years and 70% at 20 years. Global survival was 91% at 20 years. Baseline LV ejection fraction<60% was significantly associated with ventricular arrhythmia recurrence (hazard ratio 16.4, 95% confidence interval 1.8-147; P=0.01). CA can safely address macroreentrant MVT in repaired TOF patients with an acceptable long-term rate of recurrence in this high-risk population. Anatomical classification of isthmuses with electroanatomical mapping provides reproducible endpoints for CA. Attention should be given to LV systolic function in risk assessment and selection of candidates for implantable cardioverter-defibrillator. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  19. [Ten years comparison of diagnosis and treatment of asthma in urban children in China].

    Science.gov (United States)

    Sha, Li; Liu, Chuanhe; Shao, Mingjun; Chen, Yuzhi

    2016-03-01

    To compare the changes of diagnosis, treatment and control of 0-14 years old urban asthma children during 10 years. The questionnaires were given to diagnosed asthmatic children during the national epidemiological survey of asthma in children in 2000 and 2010 to understand the diagnosis and treatment of asthma and the status of the disease control. Children with asthma of a total of 36 cities were involved in this study, and the diagnosed asthma children in recent 2 years were 6,128 and 8 174, separately. Data were stored using epi-info software by double entry, V19.0 of SPSS was used to do the statistical analysis , χ(2) test was used. The proportion of correct diagnosis of asthma before investigation in 2010 was 64.6%, while it was 70.7% in 2010, which showed a significant increase (χ(2) = 59.3, P asthma onset within 1 year was separately 50.8% and 78.6% in 2000 and 2010. The early diagnostic rate was significantly higher in 2010 than that in 2000 (χ(2) = 817.7, P asthma medication in the use of inhaled corticosteroids was 36.3% and 61.7%, it increased by 0.7 times in 2010 (χ(2) = 907.5, P asthma attacks within recent 1 year were separately 86.3% and 77.0% (χ(2) = 194.0, Pasthma attack were separately 54.0% and 47.3% (χ(2) = 61.7, P asthma less than 10 days was separately 47.5% and 71.4% (χ(2) = 682.6, P asthma in urban Chinese children within 1 year had a significant increase compared with a decade ago. Inhaled corticosteroids therapy had increased by 0.7 times than before while systemic corticosteroids utilization rate significantly decreased. Antibiotics usage had a decrease of 22.0% but they were still overused. Asthma control was significantly improved, but acute exacerbations and hospitalizations of asthma children still accounts for a large proportion although they both had a great improvement.

  20. The aftermath of the population explosion: by the year 2000, a world population 40 per cent higher than today.

    Science.gov (United States)

    Salas, R M

    1982-01-01

    Original forecasts of world population size made in the 1950's assumed falling death rates and stable birth rates. Birth rates instead began to fall with world growth rates slowing from 1.99% in 1960 through 1965 to 1.72% in 1975 to 1980 and revised projection of world population by the year 2000 is now 6.1 billion, 40% higher than today. There are several reasons for this declining growth rate. Many governments now recognize the important effects population growth and spatial distribution have on a country's economic and social development and this recognition has led to the development of specific programs and policies to deal with population problems. The development and implementation of these programs has led to the recognition of several important factors in population growth. The World Fertility Survey found that employment for women and fertility are linked. Women who work, excluding the case of agricultural work, tend to have smaller families. Literacy and education affect not only the number of children a woman has but also their chances of survival. The best way to reduce birth and death rates in developing countries is by increasing the education and employment of women, improving access to health and family planning services, and to be aware of changes in attitudes to family formation. Another reason involves the effective delivery of services, especially education about sanitation. A 3rd reason is that the proportion of national budgets devoted to population planning has dramatically increased. Lastly, international assistance for population planning has doubled since 1970. There remain many problems. Although the global fertility rate has declined, many countries, especially in Africa, still have high population growth rates and low life expectancies. There are expected to be vast increases in urban populations, proportions of elderly in the population, and large international and internal migrations as people seek work further from home. What is

  1. False allegations of sexual assualt: an analysis of ten years of reported cases.

    Science.gov (United States)

    Lisak, David; Gardinier, Lori; Nicksa, Sarah C; Cote, Ashley M

    2010-12-01

    One of the most controversial disputes affecting the discourse related to violence against women is the dispute about the frequency of false allegations of sexual assault. In an effort to add clarity to the discourse, published research on false allegations is critiqued, and the results of a new study described. All cases (N = 136) of sexual assault reported to a major Northeastern university over a 10-year period are analyzed to determine the percentage of false allegations. Of the 136 cases of sexual assault reported over the 10-year period, 8 (5.9%) are coded as false allegations. These results, taken in the context of an examination of previous research, indicate that the prevalence of false allegations is between 2% and 10%.

  2. Ten years of tuberculosis intervention in Greenland - has it prevented cases of childhood tuberculosis?

    DEFF Research Database (Denmark)

    Birch, Emilie; Andersson, Mikael; Koch, Anders

    2014-01-01

    BACKGROUND: The incidence of tuberculosis (TB) disease in Greenland doubled in the 1990s. To combat the increase, national TB interventions were initiated in 2000 and strengthened in 2007. OBJECTIVE: To determine whether the effect of interventions could be detected, we estimated the TB disease...... risk among children≤15 years before and after interventions were implemented. DESIGN: For a study cohort, we recruited all children ≤15 years of age included in the Greenlandic Civil Registration System (CRS) from 1990 to 2010. The CRS identifier was used to link cohort participants with TB cases......-2010 (intensified interventions). Risk of TB was estimated using Poisson regression. RESULTS: The study included 35,858 children, of whom 209 had TB disease. The TB disease incidence decreased after interventions were implemented (2007-2010: IRR [incidence rate ratios] 0.62, 95% CI: 0.39-0.95, p=0.03, compared...

  3. Ten-year experience with the Swenson procedure in Nigerian children with Hirschsprung′s disease

    Directory of Open Access Journals (Sweden)

    Sowande Oludayo

    2011-01-01

    Full Text Available Background: Hirschsprung′s disease (HD is a common cause of intestinal obstruction in children. Definitive treatments consist of excision of the aganglionic segment and anastomosing the normal colon to the anal remnant. The outcome of this approach in Nigerian children is not known. The aim of this study was to analyze the short to mid-term outcome of children who have undergone the Swenson Procedure (SPT as a treatment of HD over a period of 10 years. Patients and Methods: The clinical data of biopsy-proven cases of HD managed at the Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria, between 1998 and 2007 were reviewed. Results: There were 33 children 28 were males and five were females (M 5.6: F = 1. The median age at presentation was eight months (range three days to 11 years. Eighteen (54.5% patients had primary pull-through without colostomy while 15 (45.5% patients had a two-staged operation. The operation was carried out at a median age of 14 months with a range of seven weeks to 11 years, four months. Twenty-one (64% of the patients were older than one year at the time of surgery. The level of aganglionosis was in the recto-sigmoid area in 30 (91% patients. The commonest post-SPT complication was intestinal obstruction from adhesions. Bowel opening varied from once daily to eight times daily, median thrice daily. Conclusion: The Swenson′s Procedure is an effective procedure in the treatment of HD in children in Ile Ife, Nigeria.

  4. Geophagia In A Ten-Year-Old African Female With HIV Infection And ...

    African Journals Online (AJOL)

    A very unusual case of geophagia in a 10 year old female patient, with a history of HIV and tuberculosis is reported. While the real prevalence and the ... La prise en charge de la géophagie consiste essentiellement à rechercher les verminoses, l\\'anémie et la déplétion en fer qui peuvent être associées. Les complications ...

  5. Tumors of the liver; a ten year study in Children Medical Center

    Directory of Open Access Journals (Sweden)

    Farahmand F

    2007-06-01

    Full Text Available Background: The aim of this study was to review the frequency, histopathology and outcome in children with tumors of the liver. Methods: Included in this retrospective/descriptive study were 30 children treated for liver tumors from 1375-1384 (ca. 1996-2005, at Children’s Hospital Medical Center, Tehran, Iran. We included the clinical, radiologic, and pathologic data of our patients, focusing on the frequency, etiology and outcome. Results: Patient ages ranged from three months to 12 years (median 3.8 years, with 18 males (60% and 12 females (40%. Of these, 17 patients had hepatoblastoma (55.66%, including 13 males and four females, with an age range of six months to five years. Four cases (13.33% had neuroblastoma. Hepatocellular carcinoma (HCC was found in three cases (10%, all of whom were carriers of hepatitis B. Two cases (6.66% were diagnosed with mesenchymal hamartoma, two cases (6.66% with hemangioendothelioma and two cases (6.66% with rhabdomyosarcoma and leiomyosarcoma of the biliary tract. Abdominal swelling and hepatomegaly were seen in all of patients. Jaundice was observed in two cases. Serum alpha-fetoprotein levels greater than 500 ng/ml were seen in 17 cases (56.66%. All patients were receiving specific treatment. The three-year survival rate was 65% for hepatoblastoma and 2% for HCC Conclusion: With the introduction of specific treatment, the survival rate for children with tumors of the liver has significantly increased. Further improvement can be achieved using diagnostic biopsy for hepatoblastoma, although it may result in complications, and preoperative chemotherapy followed by complete surgical excision (per International Society of Pediatric Oncology guidelines, yielding an outstanding survival rate of 80%.

  6. TEN YEARS FOLLOW UP OF MULTIPLE SCLEROSIS WITH PHYSIOTHERAPY – EVIDENCE BASED STUDY

    OpenAIRE

    Dr. S. S. Subramanian*

    2017-01-01

    Multiple sclerosis, a progressive neurological degenerative disease, where physical, psychological and social aspects of rehabilitation is required on long term, with periodical evaluation and physiotherapy. This original study with 10 years follow up on a subject with multiple sclerosis highlights the clinical course and high lighten the impact of physiotherapy with evidence. Though the results of this study was negative with multiple sclerosis impact scale 29 increasing, along with expanded...

  7. Enhancing Effect of Hydroxyurea on Hb F in Sickle Cell Disease: Ten-Year Egyptian Experience.

    Science.gov (United States)

    Youssry, Ilham; Abdel-Salam, Amina; Ismail, Rania; Bou-Fakhredin, Rayan; Mohamed Samy, Rania; Ezz El-Deen, Fatma; Taher, Ali T

    Patients with sickle cell disease experience hemolytic anemia and vaso-occlusions that result in pain, organ injury, and premature mortality. Several prospective studies have verified the efficacy and tolerability of hydroxyurea (HU), and demonstrated its efficacy in reducing painful vaso-occlusive crises (VOCs) in addition to its ability to increase Hb F levels. We aimed to evaluate the long-term effects of HU therapy on Hb F and assess its long term efficacy and safety in sickle cell disease patients. A retrospective study on 60 sickle cell disease patients was conducted. We studied the laboratory changes, frequency of VOCs per year, frequency of hospital admisions per year and number of transfusions per year, both before and after HU therapy. The follow-up period was 4 to 120 months. Hb F levels after HU therapy positively correlated with the duration of HU therapy, baseline Hb F levels and baseline total hemoglobin (Hb) (r = 0.4, p = 0.04; r = 0.45, p = 0.001; r = 0.5, p = 0.019, respectively) and inversely correlated with baseline total leucocyte count (r = -0.33, p = 0.034). Hydroxyurea therapy was associated with an increase in the total Hb and mean corpuscular volume (MCV) (p = 0.009, p = 0.000; respectively) and with a decrease in total leucocyte count, platelet count and reticulocyte count (p = 0.00, p = 0.03, p = 0.02, respectively). Moreover, a significant reduction in the frequency of VOCs, transfusion frequency and hospital admissions per year after HU therapy was shown in the studied subjects. Hydroxyurea induced an increase in Hb F level, which was maintained over time and was associated with clinical efficacy and acceptable safety.

  8. Human Metapneumovirus: Insights from a Ten-Year Molecular and Epidemiological Analysis in Germany

    Science.gov (United States)

    Reiche, Janine; Jacobsen, Sonja; Neubauer, Katrin; Hafemann, Susi; Nitsche, Andreas; Milde, Jeanette; Wolff, Thorsten; Schweiger, Brunhilde

    2014-01-01

    Human metapneumovirus (HMPV) is a cause of respiratory tract illness at all ages. In this study the epidemiological and molecular diversity among patients of different ages was investigated. Between 2000–2001 and 2009–2010, HMPV was detected in 3% (138/4,549) of samples from outpatients with influenza-like illness with a new, sensitive real-time RT-PCR assay. Several hundred (797) clinical specimens from hospitalized children below the age of 4 years with acute respiratory illness were investigated and HMPV was detected in 11.9% of them. Investigation of outpatients revealed that HMPV infections occurred in individuals of all ages but were most prevalent in children (0–4 years) and the elderly (>60 years). The most present clinical features of HMPV infections were cough, bronchitis, fever/shivers and pneumonia. About two thirds of HMPV-positive samples were detected in February and March throughout the study period. Molecular characterization of HMPV revealed a complex cyclic pattern of group dominance where HMPV subgroup A and B viruses predominated in general for three consecutive seasons. German HMPV represented all genetic lineages including A1, A2, B1, B2, sub-clusters A2a and A2b. For Germany, not only time-dependent circulation of lineages and sub-clusters was observed but also co-circulation of two or three predominant lineages. Two newly emerging amino acid substitutions (positions 223 and 280) of lineage B2 were detected in seven German HMPV sequences. Our study gives new insights into the molecular epidemiology of HMPV in in- and outpatients over a time period of 10 years for the first time. It is one of only few long-term surveillance studies in Europe, and allows comparative molecular analyses of HMPV circulating worldwide. PMID:24505479

  9. Clinical characteristics and outcomes of critically ill obstetric patients: a ten-year review

    OpenAIRE

    Aldawood, Abdulaziz

    2011-01-01

    BACKGROUND AND OBJECTIVES: Pregnancy and delivery can involve complications that necessitate admission to critical care facilities. The objective of our study was to assess the incidence, indications, and outcomes of obstetric patients requiring admission to an intensive care unit (ICU) in a tertiary care hospital, in Saudi Arabia. DESIGN AND SETTING: Retrospective cohort study of consecutive obstetric admissions to the ICU at the King Abdulaziz Medical City over a 10-year period. PATIENTS AN...

  10. Ten Years after the Danish Muhammad Cartoon News Stories: Terror and Radicalization as Predictable Media Events

    DEFF Research Database (Denmark)

    Hervik, Peter

    2018-01-01

    In the tenth year after Danish daily Jyllands-Posten published twelve cartoons, the Muhammad Cartoons, this media event—and the hegemonic understanding behind it—continues to be a discursive reference point for new controversies around national borders and racial boundaries. Then, since late 2010....... It keeps informing news coverage of media events as terror and thereby risking describing the hegemony more than adequately understanding the events at hand....

  11. Are breast cancer patients treated with radiotherapy younger now than ten years ago?

    Science.gov (United States)

    Bonet, Marta; Godoy, Pere; Cambra, Maria Jose; Mur, Encarna; Algara, Manel; Fernandez, Luis; Dalmau, Elsa; Arcusa, Àngels; Seguí, Miquel Àngel; Saigí, Eugeni; Gonzalez, Sònia; Cirera, Lluís; Solé, Josep Maria

    2014-01-01

    Aim The aim of the present study was to analyze the age of breast cancer patients managed with curative approach at the time of treatment with radiotherapy. Background Breast cancer is the most frequent neoplasm in women. Little is known with regard to the age of patients at diagnosis, and some authors have suggested that breast cancer is now affecting women who are younger than before. Materials and methods We performed a descriptive study of our series of breast cancer patients from 1998 to 2011. The age of patients, city of residence, year of treatment and uni- or bilateral location were extracted from the administrative database of the Radiation Oncology Department. The demographical and reference populational data were extracted from the Catalan Institute of Statistics. Results 3382 patients were obtained. The mean age was 57.79 years. No statistical differences were observed in the mean age during the period of study (p > 0.05), nor in patients with bilateral neoplasias with regard to unilateral tumours (p > 0.5). Patients aged less than 30, 40, 50 and 65 years were 0.3%, 6.3%, 27.0% and 69.1%, respectively. The proportion of patients aged less, equal or more than 40 and 50 years was not statistically different. Conclusions Breast cancer patients treated with adjuvant radiotherapy after radical surgery have not experienced significant changes in their mean age at treatment. The subgroups of patients that remain out of the mammographic screening programmes were unchanged as well. The observed differences can be explained by demographical disparities and by a probable increase in the indications for adjuvant radiotherapy. PMID:25535580

  12. Tracheostomy in children: a ten-year experience from a tertiary center in southern Brazil.

    Science.gov (United States)

    Schweiger, Cláudia; Manica, Denise; Becker, Carolina Fischer; Abreu, Larissa Santos Perez; Manzini, Michelle; Sekine, Leo; Kuhl, Gabriel

    Children may require tracheostomy due to many different health conditions. Over the last 40 years, indications of tracheostomy have endorsed substantial modifications. To evaluate pediatric patients warranted tracheostomy at our Hospital, in regard to their indications, associated comorbidities, complications and decannulation rates. Retrospective study concerning patients under 18 years of age undergoing tracheostomy in a tertiary health care center, from January 2006 to November 2015. 123 children required a tracheostomy after ENT evaluation during the study period. A proportion of 63% was male, and 56% was under one year of age. Glossoptosis was the most common indication (30%), followed by subglottic stenosis (16%) and pharyngomalacia (11%). The mortality rate was 31%. By the end of this review, 35 children (28.4%) had been decannulated, and the fewer the number of comorbidities, the greater the decannulation rate (0.77±0.84 vs. 1.7±1.00 comorbidities; pneurological conditions in this cohort. Our decannulation rate is slightly below other series, probably because of the greater amount of patients with comorbidities. Copyright © 2016 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

  13. Tracheostomy in children: a ten-year experience from a tertiary center in southern Brazil,

    Directory of Open Access Journals (Sweden)

    Cláudia Schweiger

    Full Text Available Abstract Introduction: Children may require tracheostomy due to many different health conditions. Over the last 40 years, indications of tracheostomy have endorsed substantial modifications. Objective: To evaluate pediatric patients warranted tracheostomy at our Hospital, in regard to their indications, associated comorbidities, complications and decannulation rates. Methods: Retrospective study concerning patients under 18 years of age undergoing tracheostomy in a tertiary health care center, from January 2006 to November 2015. Results: 123 children required a tracheostomy after ENT evaluation during the study period. A proportion of 63% was male, and 56% was under one year of age. Glossoptosis was the most common indication (30%, followed by subglottic stenosis (16% and pharyngomalacia (11%. The mortality rate was 31%. By the end of this review, 35 children (28.4% had been decannulated, and the fewer the number of comorbidities, the greater the decannulation rate (0.77 ± 0.84 vs. 1.7 ± 1.00 comorbidities; p < 0.001. Conclusion: Tracheostomy in children is a relatively frequent procedure at our hospital. The most common indications are glossoptosis and subglottic stenosis. A high mortality rate was found, potentially substantiated by the high number of critical care patients with chronic neurological conditions in this cohort. Our decannulation rate is slightly below other series, probably because of the greater amount of patients with comorbidities.

  14. SPIN-UP Ten Years Later: What's Still Solid and What's New

    Science.gov (United States)

    Howes, Ruth

    2010-02-01

    Seven years ago, the SPIN-UP Report produced by the National Task Force on Undergraduate Physics identified several key characteristics of undergraduate physics programs that were thriving amid a general decline in the numbers of physics majors. Since that time, the number of physics majors graduating has increased each year. Nevertheless, the rate of growth has slowed in the last several years, and many departments are threatened in the current financial crisis because of low undergraduate enrollments. All undergraduate programs face challenges of the growing use of computation in physics, the pressure from administrators and funding agencies to participate in interdisciplinary work, the lack of gender and ethnic diversity in physics, and changes in students' math preparation as well as the standard issues of large service enrollments and scarcity of resources. Therefore, this is an appropriate time to revisit the conclusions of the SPIN-UP report and consider its recommendations and new ideas to continue the growth of robust undergraduate physics programs. )

  15. Ten-year clinico-statistical study of oral squamous cell carcinoma

    International Nuclear Information System (INIS)

    Aoki, Shinjiro; Kawabe, Ryoichi; Chikumaru, Hiroshi; Saito, Tomokatsu; Hirota, Makoto; Miyake, Tetsumi; Omura, Susumu; Fujita, Kiyohide

    2003-01-01

    This clinico-statistical study includes 232 cases of oral squamous cell carcinoma that underwent radical treatment in the Department of Oral and Maxillofacial Surgery, Yokohama City University Hospital, during the decade from 1991 to 2000. Surgery was principally adopted as the first line for treatment in 199 cases, and radiotherapy in 33 cases. The 5-year overall survival rate was 73.4%. The results according to stage were as follows: stage I, 87.5%; Stage II, 77.9%; Stage III, 63.5%; and Stage IV A, 44.7%. The primary sites were classified as follows: upper gingiva, 85.2%; tongue, 73.7%; floor of mouth, 68.9%; lower gingiva, 66.3%; buccal mucosa, 63.9%; and hard palate, 50%. For tongue cancer, the 5-year overall survival rates by stage were: Stage I, 90.8%; Stage II, 82.1%; Stage III, 40.3%; and Stage IV A, 45.7%. Statistical significance was seen between cases of Stages I and II and those of Stages III and IV A stage. For lower gingival cancer, the 5-year overall survival rates by stage were: Stage I, 90.8%; Stage II, 82.1%; Stage III, 40.3%; and Stage IV A, 45.7%. Even in Stage I lower gingival cancers had unfavorable clinical outcomes. Preventive neck dissections were performed on 52 N 0 neck patients, but clinically negative nodes however showed metastasis in 14 patients (26.9%). (author)

  16. Overweight and musculoskeletal morbidity: a ten-year follow-up.

    Science.gov (United States)

    Aro, S; Leino, P

    1985-01-01

    The association of relative weight with various indices of musculoskeletal morbidity was studied in 902 Finnish white-collar and blue-collar workers. Data were collected in the years 1973 and 1983 through a postal questionnaire, by medical examination, and clinical assessment of the condition of the musculoskeletal system. In the overweight group (relative weight greater than or equal to 120 percent), higher mean levels in all musculoskeletal scores (the Musculoskeletal Symptoms Score, the Upper/Lower Extremities Score, the Low Back Score and the Musculoskeletal Findings Score) were observed, compared with the normal weight group. There was no evidence, however of rheumatic complaints in weight-bearing joints being more common in overweight individuals, contrary to the 'wear and tear' hypothesis. In a 10-year follow-up the changes in the musculoskeletal scores were analysed by stepwise multiple regression. Baseline relative weight explained 6.3 percent of the variation in the score based on clinical assessment. Neither baseline weight nor weight change were significant predictors of change in the other scores. No association was observed between overweight and lumbosacral disorders either in the cross-sectional study or in the 10-year follow-up.

  17. [Pediatric injuries from mass casualty events in Israel: a ten-year summary].

    Science.gov (United States)

    Waisman, Yehezkel; Goldman, Sharon; Poznanski, Oded; Mor, Meirav; Peleg, Kobi

    2010-07-01

    Children are the most vulnerable sub-population in mass casualty events (MCEs), however, characteristics of MCE related injuries among children have not been well described. The aim of our study was to characterize childhood injuries resulting from MCEs in Israel including parameters such as magnitude, injury mechanism and severity and use of hospital resources. We conducted a descriptive study of MCE related injuries among hospitalized children (0-17 years) between the years 1998-2007 and recorded in the Israel Trauma Registry (ITR). The main outcome measures included: body region, injury severity (ISS) and mortality rates. A total of 267 children (mean age 11.3 years, 52% girls) were hospitalized for injuries caused by 75 (47%) of the 158 MCEs recorded during the study period. The mechanisms of MCE related injury were as follows: terror-related (63%); motor vehicle collision (buses or train) (32%); a collapsed building (3%); and other mechanisms (2%). Injuries among teenagers (ages 10-17 years) were twice as high as those of younger children [ages 0-9 years), (67% and 33%, respectively (p Head and neck (67%) were the most common body regions to be injured, followed by upper and Lower extremities (62%). Most children sustained mild injuries (55% ISS 1-8), however, a significant percentage had severe to fatal injuries (29% ISS > or =16). Severe injuries were significantly more frequent among children injured in MCEs compared to non-MCE injuries: ISS 16 (29% vs. 8%, respectively p < 0.0001), in-hospital mortaLity (3.4% vs. 0.4%, respectively, p < 0.0001), underwent surgical procedures (50% vs. 20%, respectively, p < 0.05), ICU admission rate (31% vs. 6%, p < 0.0001), and longer hospital stay (median LOS 8.9 vs. 3.5 days, respectively p < 0.0001). Morbidity and mortality are significantly higher among children who are injured in MCEs than by other mechanisms. Improved pediatric pre-hospital care and hospital resources as well may enhance future pediatric MCE

  18. Ten-year longitudinal changes in retinal microvascular lesions: the atherosclerosis risk in communities study.

    Science.gov (United States)

    Liew, Gerald; Campbell, Stephen; Klein, Ronald; Klein, Barbara E K; Sharrett, A Richey; Cotch, Mary Frances; Wang, Jie Jin; Wong, Tien Y

    2011-08-01

    There are limited data on the natural history and longitudinal changes of retinal microvascular lesions. We examined 10-year changes in retinal microvascular lesions, focusing on those related to hypertension and shown to predict development of cardiovascular disease. Prospective cohort. We included 1120 middle-aged participants without diabetes of the Atherosclerosis Risk in Communities (ARIC) Study in 1993 to 1995 and again 10 years later in 2003 to 2005. Retinal microvascular lesions were graded from retinal photographs using the same protocol at both examinations, with changes (incidence or disappearance) adjudicated by a side-by-side comparison of photographs. The study sample was stratified by carotid intima media thickness (IMT) and ARIC field center; thus, all analyses were weighted by these factors. Persons with diabetes were excluded because the frequency and pathophysiology of diabetic retinal lesions is different. Incidence and disappearance rates of lesions. The 10-year incidence of focal arteriolar narrowing, arteriovenous (AV) nicking, and retinopathy in persons without diabetes was 3.4% (95% confidence interval [CI], 2.3-4.9), 2.5% (95% CI, 1.6-3.9), and 2.2% (95% CI, 1.3-3.5) respectively. Over the 10-year period, of 32, 219, and 24 eyes with focal arteriolar narrowing, AV nicking and retinopathy at baseline, 50.3% (95% CI, 28.6-71.9), 40.7% (95% CI, 32.7-49.4), and 65.9% (95% CI, 42.4-83.5), respectively, disappeared. Higher baseline plasma fibrinogen and white cell counts were associated with incident focal arteriolar narrowing; antihypertensive medication use was associated with incident AV nicking, and higher diastolic blood pressure, carotid IMT, and white cell counts were associated with incident retinopathy. Higher fasting serum glucose was not significantly associated with incident retinopathy, although this may be related to the small number of lesions (odds ratio, 5.88; 95% CI, 0.74-46.64 per standard deviation difference). In this sample

  19. Ten-year incidence of Chagas cardiomyopathy among asymptomatic Trypanosoma cruzi-seropositive former blood donors.

    Science.gov (United States)

    Sabino, Ester C; Ribeiro, Antonio L; Salemi, Vera M C; Di Lorenzo Oliveira, Claudia; Antunes, Andre P; Menezes, Marcia M; Ianni, Barbara M; Nastari, Luciano; Fernandes, Fabio; Patavino, Giuseppina M; Sachdev, Vandana; Capuani, Ligia; de Almeida-Neto, Cesar; Carrick, Danielle M; Wright, David; Kavounis, Katherine; Goncalez, Thelma T; Carneiro-Proietti, Anna Barbara; Custer, Brian; Busch, Michael P; Murphy, Edward L

    2013-03-12

    Very few studies have measured disease penetrance and prognostic factors of Chagas cardiomyopathy among asymptomatic Trypanosoma cruzi-infected persons. We performed a retrospective cohort study among initially healthy blood donors with an index T cruzi-seropositive donation and age-, sex-, and period-matched seronegatives in 1996 to 2002 in the Brazilian cities of São Paulo and Montes Claros. In 2008 to 2010, all subjects underwent medical history, physical examination, ECGs, and echocardiograms. ECG and echocardiogram results were classified by blinded core laboratories, and records with abnormal results were reviewed by a blinded panel of 3 cardiologists who adjudicated the outcome of Chagas cardiomyopathy. Associations with Chagas cardiomyopathy were tested with multivariate logistic regression. Mean follow-up time between index donation and outcome assessment was 10.5 years for the seropositives and 11.1 years for the seronegatives. Among 499 T cruzi seropositives, 120 (24%) had definite Chagas cardiomyopathy, and among 488 T cruzi seronegatives, 24 (5%) had cardiomyopathy, for an incidence difference of 1.85 per 100 person-years attributable to T cruzi infection. Of the 120 seropositives classified as having Chagas cardiomyopathy, only 31 (26%) presented with ejection fraction <50%, and only 11 (9%) were classified as New York Heart Association class II or higher. Chagas cardiomyopathy was associated (P<0.01) with male sex, a history of abnormal ECG, and the presence of an S3 heart sound. There is a substantial annual incidence of Chagas cardiomyopathy among initially asymptomatic T cruzi-seropositive blood donors, although disease was mild at diagnosis.

  20. Ten-Year Incidence of Chagas Cardiomyopathy Among Asymptomatic Trypanosoma cruzi–Seropositive Former Blood Donors

    Science.gov (United States)

    Sabino, Ester C.; Ribeiro, Antonio L.; Salemi, Vera M.C.; Di Lorenzo Oliveira, Claudio; Antunes, Andre P.; Menezes, Marcia M.; Ianni, Barbara M.; Nastari, Luciano; Fernandes, Fabio; Patavino, Giuseppina M.; Sachdev, Vandana; Capuani, Ligia; de Almeida-Neto, Cesar; Carrick, Danielle M.; Wright, David; Kavounis, Katherine; Goncalez, Thelma T.; Carneiro-Proietti, Anna Barbara; Custer, Brian; Busch, Michael P.; Murphy, Edward L.

    2013-01-01

    Background Very few studies have measured disease penetrance and prognostic factors of Chagas cardiomyopathy among asymptomatic Trypanosoma cruzi–infected persons. Methods and Results We performed a retrospective cohort study among initially healthy blood donors with an index T cruzi–seropositive donation and age-, sex-, and period-matched seronegatives in 1996 to 2002 in the Brazilian cities of São Paulo and Montes Claros. In 2008 to 2010, all subjects underwent medical history, physical examination, ECGs, and echocardiograms. ECG and echocardiogram results were classified by blinded core laboratories, and records with abnormal results were reviewed by a blinded panel of 3 cardiologists who adjudicated the outcome of Chagas cardiomyopathy. Associations with Chagas cardiomyopathy were tested with multivariate logistic regression. Mean follow-up time between index donation and outcome assessment was 10.5 years for the seropositives and 11.1 years for the seronegatives. Among 499 T cruzi seropositives, 120 (24%) had definite Chagas cardiomyopathy, and among 488 T cruzi seronegatives, 24 (5%) had cardiomyopathy, for an incidence difference of 1.85 per 100 person-years attributable to T cruzi infection. Of the 120 seropositives classified as having Chagas cardiomyopathy, only 31 (26%) presented with ejection fraction <50%, and only 11 (9%) were classified as New York Heart Association class II or higher. Chagas cardiomyopathy was associated (P<0.01) with male sex, a history of abnormal ECG, and the presence of an S3 heart sound. Conclusions There is a substantial annual incidence of Chagas cardiomyopathy among initially asymptomatic T cruzi–seropositive blood donors, although disease was mild at diagnosis. PMID:23393012

  1. Ten-year survival and success rate of implant-prosthodontic treatment

    Directory of Open Access Journals (Sweden)

    Nataša Ihan Hren

    2013-12-01

    Full Text Available Introduction: Implant-prosthodontic treatment for restoring a single missing tooth, partial edentulism and complete edentulism is a predictive and successful method in terms of both the survival rate of implants and the different parameters which determine the success rate of the treatment. The purpose of this study was to evaluate the 10-year survival and success rates of dental implants, analyze the causes of early and late complications, and assess the type and number of prosthodontic complications.Patients and methods: In 51 patients, 113 titanium dental implants were inserted by one surgeon using a two-stage surgical protocol. The prosthodontic treatment included fixed or removable treatment options. Implant survival and success were evaluated 10 years after the completion of prosthodontic treatment. The evaluation comprised history, clinical examination with assessment of success parameters (prosthesis functionality, peri-implant tissue status, and x-ray assessment of bone loss.Results: Two implants were lost before and two 10 years after the prosthodontic treatment. The survival rate of implants was 96.4 % on the average, 100 % in the lower jaw, and 92.5 % in the upper jaw. Peri-implantitis was diagnosed in 4.5 % of all implants. The success rate was thus 95.5 %. Technical complications occurred in 2.8 % of fixed prostheses and 19 % of removable prostheses.Conclusion: The long-term survival and success rates of dental implants are high. Proper implant prosthodontic treatment planning is crucial to achieving high survival and success rates of implant treatment. Bone quality has to be taken into account when implant treatment is performed. Peri-implantitis is rarely observed, and prosthodontic complications are uncommon. On completion of the surgical and prosthetic phases of treatment, patients must be followed at regular intervals to ensure timely management of complications.

  2. Ten-year epidemiology of chemical burns in western Zhejiang Province, China.

    Science.gov (United States)

    Ye, Chunjiang; Wang, Xingang; Zhang, Yuanhai; Ni, Liangfang; Jiang, Ruiming; Liu, Liping; Han, Chunmao

    2016-05-01

    Chemical burns occur frequently in western Zhejiang Province. This study documents the epidemiology of chemical burns in the region using burn data from a local specialized hospital. Results from this analysis will assist in the planning of prevention strategies for high-risk occupations and groups. A 10-year retrospective analysis was conducted for all patients with chemical burns admitted to the Department of Burn and Plastic Surgery from January 2004 to December 2013. Information obtained for each patient included demographics (gender, age, occupation and education), location of the burn, cause of the burn, and categories of chemicals. Data regarding the season of admittance, prehospital treatment, wound site/size (area, region, and depth), accompanying injuries, operations, length of hospital stay and mortality were also assessed. A total of 690 patients (619 males, 71 females; average age: 30.6±12.4 years) were admitted to the department for chemical burns. Over the 10-year period, the incidence of chemical burns showed an increasing tendency. Chemical burns occurred most frequently in patients aged 20-59 years (94.79%). Most of the chemical burns were work-related, primarily in private enterprises (47.97%) and state-owned enterprises (24.93%). Operations (68.99%) and machine problems (17.26%) were the main causes of chemical burns in the workplace. With regard to burns caused by chemicals, most were caused by acids (72.01%), with hydrofluoric acid and sulphuric acid causing 51.45%. Most chemical burns occurred in the summer and autumn seasons (61.02%). The burn size was 40% TBSA. The most common burn sites were the upper extremities (31.57%), lower extremities (19.86%), and head and neck (28.83%). Most patients (581 (84.20%)) received water washing treatment on site immediately after exposure. The most common accompanying injuries included inhalation injury, ocular burns and digestive tract injury. The average hospital stay was 17.0±23.1 days (range 1

  3. Ten Years of MISR Observations from Terra: Looking Back, Ahead, and in Between

    Science.gov (United States)

    Diner, David J.; Ackerman, Thomas P.; Braverman, Amy J.; Bruegge, Carol J.; Chopping, Mark J.; Clothiaux, Eugene E.; Davies, Roger; Di Girolamo, Larry; Kahn, Ralph A.; Knyazikhin, Yuri; hide

    2010-01-01

    The Multi-angle Imaging SpectroRadiometer (MISR) instrument has been collecting global Earth data from NASA's Terra satellite since February 2000. With its nine along-track view angles, four visible/near-infrared spectral bands, intrinsic spatial resolution of 275 m, and stable radiometric and geometric calibration, no instrument that combines MISR's attributes has previously flown in space. The more than 10-year (and counting) MISR data record provides unprecedented opportunities for characterizing long-term trends in aerosol, cloud, and surface properties, and includes 3-D textural information conventionally thought to be accessible only to active sensors.

  4. Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress

    Science.gov (United States)

    Milad, Mohammed R.; Quirk, Gregory J.

    2016-01-01

    The psychology of extinction has been studied for decades. Approximately 10 years ago, however, there began a concerted effort to understand the neural circuits of extinction of fear conditioning, in both animals and humans. Progress during this period has been facilitated by an unusual degree of coordination between rodent and human researchers examining fear extinction. This successful research program could serve as a model for translational research in other areas of behavioral neuroscience. Here we review the major advances and highlight new approaches to understanding and exploiting fear extinction. PMID:22129456

  5. Breeding Bird Community Continues to Colonize Riparian Buffers Ten Years after Harvest.

    Science.gov (United States)

    Pearson, Scott F; Giovanini, Jack; Jones, Jay E; Kroll, Andrew J

    2015-01-01

    Riparian ecosystems integrate aquatic and terrestrial communities and often contain unique assemblages of flora and fauna. Retention of forested buffers along riparian habitats is a commonly employed practice to reduce potential negative effects of land use on aquatic systems. However, very few studies have examined long-term population and community responses to buffers, leading to considerable uncertainty about effectiveness of this practice for achieving conservation and management outcomes. We examined short- (1-2 years) and long-term (~10 years) avian community responses (occupancy and abundance) to riparian buffer prescriptions to clearcut logging silvicultural practices in the Pacific Northwest USA. We used a Before-After-Control-Impact experimental approach and temporally replicated point counts analyzed within a Bayesian framework. Our experimental design consisted of forested control sites with no harvest, sites with relatively narrow (~13 m) forested buffers on each side of the stream, and sites with wider (~30 m) and more variable width unharvested buffer. Buffer treatments exhibited a 31-44% increase in mean species richness in the post-harvest years, a pattern most evident 10 years post-harvest. Post-harvest, species turnover was much higher on both treatments (63-74%) relative to the controls (29%). We did not find evidence of local extinction for any species but found strong evidence (no overlap in 95% credible intervals) for an increase in site occupancy on both Narrow (short-term: 7%; long-term 29%) and Wide buffers (short-term: 21%; long-term 93%) relative to controls after harvest. We did not find a treatment effect on total avian abundance. When assessing relationships between buffer width and site level abundance of four riparian specialists, we did not find strong evidence of reduced abundance in Narrow or Wide buffers. Silviculture regulations in this region dictate average buffer widths on small and large permanent streams that range from

  6. Breeding Bird Community Continues to Colonize Riparian Buffers Ten Years after Harvest.

    Directory of Open Access Journals (Sweden)

    Scott F Pearson

    Full Text Available Riparian ecosystems integrate aquatic and terrestrial communities and often contain unique assemblages of flora and fauna. Retention of forested buffers along riparian habitats is a commonly employed practice to reduce potential negative effects of land use on aquatic systems. However, very few studies have examined long-term population and community responses to buffers, leading to considerable uncertainty about effectiveness of this practice for achieving conservation and management outcomes. We examined short- (1-2 years and long-term (~10 years avian community responses (occupancy and abundance to riparian buffer prescriptions to clearcut logging silvicultural practices in the Pacific Northwest USA. We used a Before-After-Control-Impact experimental approach and temporally replicated point counts analyzed within a Bayesian framework. Our experimental design consisted of forested control sites with no harvest, sites with relatively narrow (~13 m forested buffers on each side of the stream, and sites with wider (~30 m and more variable width unharvested buffer. Buffer treatments exhibited a 31-44% increase in mean species richness in the post-harvest years, a pattern most evident 10 years post-harvest. Post-harvest, species turnover was much higher on both treatments (63-74% relative to the controls (29%. We did not find evidence of local extinction for any species but found strong evidence (no overlap in 95% credible intervals for an increase in site occupancy on both Narrow (short-term: 7%; long-term 29% and Wide buffers (short-term: 21%; long-term 93% relative to controls after harvest. We did not find a treatment effect on total avian abundance. When assessing relationships between buffer width and site level abundance of four riparian specialists, we did not find strong evidence of reduced abundance in Narrow or Wide buffers. Silviculture regulations in this region dictate average buffer widths on small and large permanent streams that

  7. Overview of ten-year operation of the superconducting linear accelerator at the Spallation Neutron Source

    Science.gov (United States)

    Kim, S.-H.; Afanador, R.; Barnhart, D. L.; Crofford, M.; Degraff, B. D.; Doleans, M.; Galambos, J.; Gold, S. W.; Howell, M. P.; Mammosser, J.; McMahan, C. J.; Neustadt, T. S.; Peters, C.; Saunders, J. W.; Strong, W. H.; Vandygriff, D. J.; Vandygriff, D. M.

    2017-04-01

    The Spallation Neutron Source (SNS) has acquired extensive operational experience of a pulsed proton superconducting linear accelerator (SCL) as a user facility. Numerous lessons have been learned in its first 10 years operation to achieve a stable and reliable operation of the SCL. In this paper, an overview of the SNS SCL design, qualification of superconducting radio frequency (SRF) cavities and ancillary subsystems, an overview of the SNS cryogenic system, the SCL operation including SCL output energy history and downtime statistics, performance stability of the SRF cavities, efforts for SRF cavity performance recovery and improvement at the SNS, and maintenance activities for cryomodules are introduced.

  8. Kicking Back Cognitive Ageing: Leg Power Predicts Cognitive Ageing after Ten Years in Older Female Twins.

    Science.gov (United States)

    Steves, Claire J; Mehta, Mitul M; Jackson, Stephen H D; Spector, Tim D

    2016-01-01

    Many observational studies have shown a protective effect of physical activity on cognitive ageing, but interventional studies have been less convincing. This may be due to short time scales of interventions, suboptimal interventional regimes or lack of lasting effect. Confounding through common genetic and developmental causes is also possible. We aimed to test whether muscle fitness (measured by leg power) could predict cognitive change in a healthy older population over a 10-year time interval, how this performed alongside other predictors of cognitive ageing, and whether this effect was confounded by factors shared by twins. In addition, we investigated whether differences in leg power were predictive of differences in brain structure and function after 12 years of follow-up in identical twin pairs. A total of 324 healthy female twins (average age at baseline 55, range 43-73) performed the Cambridge Neuropsychological Test Automated Battery (CANTAB) at two time points 10 years apart. Linear regression modelling was used to assess the relationships between baseline leg power, physical activity and subsequent cognitive change, adjusting comprehensively for baseline covariates (including heart disease, diabetes, blood pressure, fasting blood glucose, lipids, diet, body habitus, smoking and alcohol habits, reading IQ, socioeconomic status and birthweight). A discordant twin approach was used to adjust for factors shared by twins. A subset of monozygotic pairs then underwent magnetic resonance imaging. The relationship between muscle fitness and brain structure and function was assessed using linear regression modelling and paired t tests. A striking protective relationship was found between muscle fitness (leg power) and both 10-year cognitive change [fully adjusted model standardised β-coefficient (Stdβ) = 0.174, p = 0.002] and subsequent total grey matter (Stdβ = 0.362, p = 0.005). These effects were robust in discordant twin analyses, where within

  9. Trends in types of dermatology books available over the last ten years.

    Science.gov (United States)

    Aquino, Lisa L; Wu, Jashin J

    2009-06-15

    Shifts in interest toward cosmetic and surgical dermatology and away from medical and academic dermatology have been observed in recent years. We hypothesized that this trend would be evident in the types of books available for purchase from a major medical textbook supplier. Books published from 1998-2008 were categorized by type and statistical testing was performed to determine if this trend has been reflected in books published. The percentage of medical dermatology books decreased over time, whereas the percentage of cosmetic and surgical dermatology books increased over time.

  10. Ten years of flight service with DC-10 composite rudders - A backward glance

    Science.gov (United States)

    Hawley, Arthur V.

    1986-01-01

    Carbon-epoxy upper aft rudders have been successfully evaluated on the DC-10 during 10 years of airline flight service. They have flown for more than 320,000 flight hours, with 36,000 flight hours flown by a single rudder. The rudder box is of thin-skin buckled construction and is cocured out-of-autoclave as a one-piece assembly. Weight saving can exceed the rudder weight if full advantage is taken of removing balance weight from the forward rudder.

  11. Ten years's reactor operation at the Technical University Zittau - operation report

    International Nuclear Information System (INIS)

    Konschak, K.

    1990-01-01

    The Zittau Training and Research Reactor ZLFR is in use for purposes of teaching the engineers who will operate the nuclear power plants in the GDR since 10 years. Since commissioning it was started up more than 1600 times, approximately two thirds of the start-ups being utilized for purposes of teaching. A number of teaching experiments were installed that demonstrate fundamental technological processes in nuclear reactors in a manner easy to understand. The high level of nuclear safety manifests itself, among other things, in extremely low radiation exposures of the operating personal and the persons to be trained. (author)

  12. Ten-year detection rate of brain arteriovenous malformations in a large, multiethnic, defined population.

    Science.gov (United States)

    Gabriel, Rodney A; Kim, Helen; Sidney, Stephen; McCulloch, Charles E; Singh, Vineeta; Johnston, S Claiborne; Ko, Nerissa U; Achrol, Achal S; Zaroff, Jonathan G; Young, William L

    2010-01-01

    To evaluate whether increased neuroimaging use is associated with increased brain arteriovenous malformation (BAVM) detection, we examined detection rates in the Kaiser Permanente Medical Care Program of northern California between 1995 and 2004. We reviewed medical records, radiology reports, and administrative databases to identify BAVMs, intracranial aneurysms (IAs: subarachnoid hemorrhage [SAH] and unruptured aneurysms), and other vascular malformations (OVMs: dural fistulas, cavernous malformations, Vein of Galen malformations, and venous malformations). Poisson regression (with robust standard errors) was used to test for trend. Random-effects meta-analysis generated a pooled measure of BAVM detection rate from 6 studies. We identified 401 BAVMs (197 ruptured, 204 unruptured), 570 OVMs, and 2892 IAs (2079 SAHs and 813 unruptured IAs). Detection rates per 100 000 person-years were 1.4 (95% CI, 1.3 to 1.6) for BAVMs, 2.0 (95% CI, 1.8 to 2.3) for OVMs, and 10.3 (95% CI, 9.9 to 10.7) for IAs. Neuroimaging utilization increased 12% per year during the time period (PIAs (PIAs (PIAs in this large, multiethnic population were similar to those in other series. During 1995 to 2004, a period of increasing neuroimaging utilization, we did not observe an increased rate of detection of unruptured BAVMs, despite increased detection of unruptured IAs.

  13. 222Rn in private well water in the vicinity of uranium mines over ten years

    International Nuclear Information System (INIS)

    Yunoki, Eiji; Kataoka, Toshio; Michihiro, Kenshu; Sugiyama, Hirokazu; Shimizu, Mitsuo; Mori, Tadashige

    1994-01-01

    There are many small uranium mines of the sedimentary type in Kamisaibara, Okayama Prefecture, Japan. As inhabitants in Kamisaibara consume water from privately-dug wells, it is important to investigate distributions of 222 Rn in privately-dug well water in the vicinity of the mines. The determination of 222 Rn in well water was carried out from April 1980 to October 1990. Though small in area (16 km 2 ), each well water has its own characteristic activity concentrations of 222 Rn. The activity concentrations of 222 Rn are almost constant for each specific well over a long period (about 10 years). In general, the correlation coefficients for several sampling points are small. As Akawase and Tennoh are situated in the same rock type, the correlation coefficient is the highest value in this area. The estimated dose equivalent for the human stomach is approximately 0.4-54 μSv/year. The type of distribution of 222 Rn in privately-dug well water is log normal. (author)

  14. Systemic lupus erythematosus pregnancies: ten-year data from a single centre in Malaysia.

    Science.gov (United States)

    Teh, C L; Wan, S A; Cheong, Y K; Ling, G R

    2017-02-01

    We performed a retrospective study of all systemic lupus erythematosus (SLE) pregnancies during a 10-year period (2006-2015) to describe the clinical features, maternal and foetal outcomes in our centre. There were 115 pregnancies in 86 women with SLE. Our patients had a mean age of 29.1 years (SD 5.80) and a mean disease duration of 44.63 months (SD 41.17). Fifteen patients had antiphospholipid syndrome (APS). Our patients had complicated pregnancies: 26.1% had SLE flares, 13.9% had pre-eclampsia and 45.1% needed caesarean sections. There were 23.3% foetal losses and 25% preterm deliveries in our patients. There was a higher rate of unplanned pregnancies and lupus flare among pregnancies with active SLE at conception. Pregnancies in lupus nephritis have higher incidence of lupus flares during pregnancy but similar maternal and foetal outcomes compared to those without nephritis. The prognostic indicators for adverse foetal outcome in our patients were flare of SLE (HR 4.08 [CI 95% 1.65-10.13, p Lupus pregnancies in our centre remained as high-risk pregnancies with significant maternal and foetal complications.

  15. Ego-resiliency development from late adolescence to emerging adulthood: A ten-year longitudinal study.

    Science.gov (United States)

    Alessandri, Guido; Eisenberg, Nancy; Vecchione, Michele; Caprara, Gian Vittorio; Milioni, Michela

    2016-07-01

    This study examined the development of ego-resiliency from late adolescence to emerging adulthood, using a 10-year cohort-sequential design. Participants were 335 Italian adolescents (173 females and 162 males), living, at the time of the study, in Genzano, a small city near to Rome. Latent growth curve analyses indicated that the developmental trajectory of ego-resiliency from 15 to 25 years is adequately described by a piecewise model that included separate growth profiles corresponding to different developmental stages. Essentially, ego-resiliency remained remarkably stable until the end of high school, and then encountered a phase of relative increase. Moreover, the trajectory of ego-resiliency from ages 15 to 19 was predicted by self-efficacy beliefs in managing negative emotions, and the trajectory from age 19 to 25 was predicted by experienced familial support and self-efficacy beliefs in expressing positive emotions at age 15. Experienced stressful life events also accounted for individuals' deviation from the typical ego-resiliency trajectory. Copyright © 2016 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  16. Nasopharyngeal carcinoma treated by radical radiotherapy alone: Ten-year experience of a single institution

    International Nuclear Information System (INIS)

    Yi Junlin; Gao Li; Huang Xiaodong; Li Suyan; Luo Jinwei; Cai Weiming; Xiao Jianping; Xu Guozhen

    2006-01-01

    Purpose: To report on our experience in the treatment of nasopharyngeal carcinoma (NPC) by radical radiotherapy alone in our institution during the last decade. Methods and Materials: From January 1990 to May 1999, 905 NPC patients were treated and were studied retrospectively. Radical radiotherapy was given to this cohort by conventional technique in a routine dose of 70-72 Gy to the primary tumor and metastatic lymph nodes. In case of residual primary lesion, a boost dose of 8-24 Gy was delivered by either 192 Ir afterloading brachytherapy, fractionated stereotactic radiotherapy, conformal radiotherapy, or small external-beam fields. Results: The 5-year and 10-year local-regional control, overall survival, and disease-free survival rates were 81.7% and 76.7%, 76.1% and 66.5%, 58.4% and 52.1%, respectively. In case of residual primary lesions after a dose of 70-72 Gy of conventional external-beam radiotherapy (EBRT), an additional boost was able to achieve a local control of 80.8%, similar to that obtained with primary lesions that completely disappeared at 70-72 Gy (82.6%, p = 0.892). Conclusions: The treatment results of radical EBRT followed by a boost dose to the residual primary tumor for nasopharyngeal carcinoma in our institution are promising

  17. [Ten years of emergency attendances for cocaine-users in Spain].

    Science.gov (United States)

    Galicia, Miguel; Nogué, Santiago; Burillo-Putze, Guillermo

    2014-10-07

    Cocaine is the second most consumed illegal drug in the western world, following cannabis. Since 1998, it is also the drug that more attendances generate in different emergency devices, and it is responsible for more of 60% of the emergencies directly related to drug consumption. This work reviews the main Spanish scientific articles published in the last 10 years, in which different factors related to the use of this drug have been analyzed in relation to the use of emergency by cocaine users. A total of 8,795 patients were included (interval 57-1,755), with an average age of 32.64 years (SD 3.02), and an average percentage of positives to cocaine of 54.78% (SD 47.03); there were 7 works with 100% of subjects being positive to cocaine. Males predominated with an average of 78.69% (SD 12). They presented cardiovascular symptoms in 30% cases (SD 22.7), neurological symptoms in 11.6% cases (SD 4.28) and psychiatric symptoms in 49.32% cases (SD 23.87). There was a multiple consumption in 49.02% of patients (interval 4.3-76.2), fundamentally associated with alcohol (57.78%, SD 6.18) and cannabis (21.56%, SD 10.72). Two hundred and forty-six patients (2.8%) needed admission and 8 died (0.09%). Copyright © 2013 Elsevier España, S.L.U. All rights reserved.

  18. Ten years of radiometric monitoring in water samples in Uruguay potables plants

    International Nuclear Information System (INIS)

    Perruni, P.

    2000-01-01

    The work exposes the summary of having been radiometrics obtained during the last 10 years in several water treatment plants of the national territory, with the purpose of determining if in the total dose to the one that this exposed one naturally the population of the country, is important the contribution of polluting radioactives in the drinkable water, in function of the geographical area and the time of the year. The investigation is framed inside the Program of Control Radiometrics of Products of Fission in waters, floors, foods and aerosols of the Uruguay developed by the Radiochemistry Department, of the Nuclear Research Center, Montevideo (UY) The samples of water filter, they process and they analyze according to laboratory protocols, had duplicated by each plant, parallel with radio-active, white bottom measures and standards. The results net average obtained for each factory, gave below the one it limits of detection: 2 BQ/Kg for geometry Marinelli and 0.02 BQ/g for plane geometry, with 99,3% of dependability (standard 3 deviations), very below the maximum values admitted by International Organisms (WHO, FAO, ICRP) [es

  19. How to identify randomized controlled trials in MEDLINE: ten years on*

    Science.gov (United States)

    Glanville, Julie M.; Lefebvre, Carol; Miles, Jeremy N. V.; Camosso-Stefinovic, Janette

    2006-01-01

    Objective: The researchers sought to assess whether the widely used 1994 Cochrane Highly Sensitive Search Strategy (HSSS) for randomized controlled trials (RCTs) in MEDLINE could be improved in terms of sensitivity, precision, or parsimony. Methods: A gold standard of 1,347 RCT records and a comparison group of 2,400 non-trials were randomly selected from MEDLINE. Terms occurring in at least 1% of RCT records were identified. Fifty percent of the RCT and comparison group records were randomly selected, and the ability of the terms to discriminate RCTs from non-trial records was determined using logistic regression. The best performing combinations of terms were tested on the remaining records and in MEDLINE. Results: The best discriminating term was “Clinical Trial” (Publication Type). In years where the Cochrane assessment of MEDLINE records had taken place, the strategies identified few additional unindexed records of trials. In years where Cochrane assessment has yet to take place, “Randomized Controlled Trial” (Publication Type) proved highly sensitive and precise. Adding six more search terms identified further, unindexed trials at reasonable levels of precision and with sensitivity almost equal to the Cochrane HSSS. Conclusions: Most reports of RCTs in MEDLINE can now be identified easily using “Randomized Controlled Trial” (Publication Type). More sensitive searches can be achieved by a brief strategy, the Centre for Reviews and Dissemination/Cochrane Highly Sensitive Search Strategy (2005 revision). PMID:16636704

  20. Ten-year survey of program directors: trends, challenges, and mentoring in prosthodontics. Part 1.

    Science.gov (United States)

    Munoz, Deborah M; Kinnunen, Taru; Chang, Brian M; Wright, Robert F

    2011-10-01

    This study consisted of two parts. Part 1 was a survey of US program directors, and Part 2 reports on the survey findings distributed to the deans of US dental schools. Both surveys evaluated observations of trends in prosthodontic education. The first survey (2005) of program directors and deans was published in 2007. This second survey was conducted in 2009. The 2009 survey provided 10-year data on trends in prosthodontics as reported by program directors. A national e-mail survey of 46 program directors was used to collect enrollment data for years 1 to 3 of prosthodontics training for US and international dental school graduates, the total number of applicants and applications considered, and the trends over time of applicants to prosthodontics for US dental school graduates and for international graduates. In addition, the program directors were asked to rank 13 key factors that may have contributed to any changes in the prosthodontic applicant pool. Program directors were also asked for information on student financial incentives and whether their programs were state or federally funded, and whether their sponsoring institution was a dental school. Of the 46 program directors, 40 responded, for an 87% response rate. Respondents reported that 66% of their enrollees were graduates of US dental schools. Between 2000 and 2009 the applicant pool in prosthodontics nearly doubled, with 50% of the program directors reporting an increase in US-trained applicants, 42.5% reporting no change, and only 7.5% reporting a decrease. Using the Spearman correlation for the 10-year survey, there was a positive, statistically significant correlation that society's demand for a higher level of training and credentialing and interest in prosthodontics among dental students contributed to an increase in the number of US dental graduates applying to prosthodontic programs. Only four programs offered no financial packages to offset tuition. The remaining 36 respondents reported some

  1. Renewables 2015 global status report - Annual Reporting on Renewables: Ten years of excellence

    International Nuclear Information System (INIS)

    Sawin, Janet L.; Sverrisson, Freyr; Rickerson, Wilson; Lins, Christine; Williamson, Laura E.; Adib, Rana; Murdock, Hannah E.; Musolino, Evan; Hullin, Martin; Reith, Ayla; Valero, Alana; Mastny, Lisa; Petrichenko, Ksenia; Seyboth, Kristin; Skeen, Jonathan; Sovacool, Benjamin; Wouters, Frank; Martinot, Eric

    2015-01-01

    Renewable energy continued to grow in 2014 against the backdrop of increasing global energy consumption, particularly in developing countries, and a dramatic decline in oil prices during the second half of the year. Despite rising energy use, for the first time in four decades, global carbon emissions associated with energy consumption remained stable in 2014 while the global economy grew; this stabilisation has been attributed to increased penetration of renewable energy and to improvements in energy efficiency. Globally, there is growing awareness that increased deployment of renewable energy (and energy efficiency) is critical for addressing climate change, creating new economic opportunities, and providing energy access to the billions of people still living without modern energy services. Although discussion is limited to date, renewables also are an important element of climate change adaptation, improving the resilience of existing energy systems and ensuring delivery of energy services under changing climatic conditions. Renewable energy provided an estimated 19.1% of global final energy consumption in 2013, and growth in capacity and generation continued to expand in 2014. Heating capacity grew at a steady pace, and the production of bio-fuels for transport increased for the second consecutive year, following a slowdown in 2011-2012. The most rapid growth, and the largest increase in capacity, occurred in the power sector, led by wind, solar PV, and hydropower. Growth has been driven by several factors, including renewable energy support policies and the increasing cost-competitiveness of energy from renewable sources. In many countries, renewables are broadly competitive with conventional energy sources. At the same time, growth continues to be tempered by subsidies to fossil fuels and nuclear power, particularly in developing countries. Although Europe remained an important market and a centre for innovation, activity continued to shift towards other

  2. Barrett's esophagus: Ten years of experience at a tertiary care hospital center in Mexico.

    Science.gov (United States)

    Valdovinos-Andraca, F; Bernal-Méndez, A R; Barreto-Zúñiga, R; Briseño-García, D; Martínez-Lozano, J A; Romano-Munive, A F; Elizondo-Rivera, J; Téllez-Ávila, F I

    The prevalence of Barrett's esophagus has been calculated at between 1.3 and 1.6%. There is little information with respect to this in Mexico. To determine the frequency and characteristics of Barrett's esophagus in patients that underwent endoscopy at a national referral center, within a 10-year time frame. The databases of the pathology and gastrointestinal endoscopy departments of the Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán" were analyzed, covering the period of January 2002 to December 2012. Patients with a histologic diagnosis of Barrett's esophagus were included. The variables of age, sex, the presence of dysplasia/esophageal adenocarcinoma, Barrett's esophagus length, and follow-up were analyzed. Of 43,639 upper gastrointestinal endoscopies performed, 420 revealed Barrett's esophagus, corresponding to a frequency of 9.6 patients for every 1,000 endoscopies. Of those patients, 66.9% (n=281) were men, mean patient age±SD was 57.2±15.3 years, 223 patients (53%) presented with long-segment Barrett's esophagus, and 197 (47%) with short-segment Barrett's esophagus. Dysplasia was not present in 339 patients (80.7%). Eighty-one (19.3%) patients had some grade of dysplasia or cancer: 48/420 (11.42%) presented with low-grade dysplasia, 20/420 (4.76%) with high-grade dysplasia, and 13/420 (3.1%) were diagnosed with esophageal cancer arising from Barrett's esophagus. Mean follow-up time was 5.6 years. The frequency of Barrett's esophagus was 9.6 cases for every 1,000 upper gastrointestinal endoscopies performed. Dysplasia was not documented in the majority of the patients with Barrett's esophagus and they had no histopathologic changes during follow-up. A total of 19.3% of the patients presented with dysplasia or cancer. Copyright © 2017 Asociación Mexicana de Gastroenterología. Publicado por Masson Doyma México S.A. All rights reserved.

  3. Ten-Year Retrospective Longitudinal-Study of Student Perspectives on Value of REU

    Science.gov (United States)

    Slater, T. F.; Slater, S. J.

    2013-12-01

    For more than two decades, federal agencies have been enthusiastically supporting summer research experiences for undergraduates. These REU programs are tacitly intended to increase retention and provide "an important educational experience" for undergraduates, particularly women, minorities and underrepresented groups. Numerous authors (viz., Laursen, Lopatto, Dolan, among many others) have enthusiastically described positive impacts of summer REU programs from exit interview data. These results include enhanced persistence to pursue STEM careers and confirmed desire to attend graduate school in the field targeted by a particular REU. Perhaps surprisingly, negative student experiences are rarely described in the scholarly literature, but do appear in more informal publications (viz., Gueterma, 2007). One wonders how REU alumni, looking back over their entire collective portfolio of experiences, now perceive the educational value of their REU experience relative to their other educational experiences. To obtain a backwards-looking, reflective description from REU alumni on the value of their REU experiences, we conducted a 10-year, two-stage study was designed to explore the ways in which the REU acted as an educational experience for 51 women from a single geoscience sub-discipline. The first phase was an ex post facto longitudinal analysis of data, including multiple interviews with each participant during their REU, annual open-ended alumni surveys, faculty interviews, and extensive field notes, over a 10-year period. This analysis informed the second phase, a clinical interview. Over 10 hours of interviews with 8 participants were conducted and analyzed. These 8 participants were selected to represent a variety of career stages, and for their potential to reflect on a wide variety of educational experiences. Results from the interviews, done many years after their REU experience, indicate that the interviewees' REU did not provide a substantive educational

  4. Duration of Sexual Harassment and Generalized Harassment in the Workplace Over Ten Years: Effects on Deleterious Drinking Outcomes

    Science.gov (United States)

    McGinley, Meredith; Richman, Judith A.; Rospenda, Kathleen M.

    2012-01-01

    While harassment in the workplace has been linked to deleterious drinking outcomes, researchers have yet to examine the long-term effects of chronic workplace harassment. During a ten year longitudinal mail survey, university employees (N = 2265) were administered measures of sexual harassment, generalized workplace harassment, and problematic drinking. Using growth mixture modeling, two latent classes of workplace harassment emerged: infrequent and chronic. Demographic characteristics (gender, age, and race) predicted the shape of the trajectories and likelihood of class membership. As hypothesized, membership in the chronic harassment classes was linked to future problematic drinking, even after controlling for previous drinking. PMID:21745045

  5. French experience in operating pressurized water reactor power stations. Ten years' operation of the Ardennes power station

    International Nuclear Information System (INIS)

    Teste du Bailler, A.; Vedrinne, J.F.

    1978-01-01

    In the paper the experience gained over ten years' operation of the Ardennes (Chooz) nuclear power station is summarized from the point of view of monitoring and control equipment. The reactor was the first pressurized water reactor to be installed in France; it is operated jointly by France and Belgium. The equipment, which in many cases consists of prototypes, was developed for industrial use and with the experience that has now been gained it is possible to evaluate its qualities and defects, the constraints which it imposes and the action that has to be taken in the future. (author)

  6. Ten Years of Vegetation Change in Northern California Marshlands Detected using Landsat Satellite Image Analysis

    Science.gov (United States)

    Potter, Christopher

    2013-01-01

    The Landsat Ecosystem Disturbance Adaptive Processing System (LEDAPS) methodology was applied to detected changes in perennial vegetation cover at marshland sites in Northern California reported to have undergone restoration between 1999 and 2009. Results showed extensive contiguous areas of restored marshland plant cover at 10 of the 14 sites selected. Gains in either woody shrub cover and/or from recovery of herbaceous cover that remains productive and evergreen on a year-round basis could be mapped out from the image results. However, LEDAPS may not be highly sensitive changes in wetlands that have been restored mainly with seasonal herbaceous cover (e.g., vernal pools), due to the ephemeral nature of the plant greenness signal. Based on this evaluation, the LEDAPS methodology would be capable of fulfilling a pressing need for consistent, continual, low-cost monitoring of changes in marshland ecosystems of the Pacific Flyway.

  7. Ten years of unitization in Brazil; Dez anos de unitizacoes no Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Bonolo, Daniel Dellamora; Almeida, Mateus Passeri de [Petroleo Brasileiro S.A. (PETROBRAS), Rio de Janeiro, RJ (Brazil)

    2012-07-01

    The unitization concept, as used by the oil industry, was established in Brazil through Art 27 of the Law 9.478/97, also known as the Petroleum Law, and the first process was initiated in 2002. Within these 10 years, four processes were started and finalized, approved by ANP. These processes were developed in a maturing regulatory environment, which was improved in 2010. This article deals with the peculiarities of these processes, putting in context the regulatory framework and doubts at the time. We also verse about the regulatory scene after 2010, pointing out the main enhancements made. It is concluded that, although essential, an elaborated regulation is not the only important factor for the success of a unitization agreement, but also the agreement between parties, which has been encouraged by ANP.(author)

  8. Ten years optically pumped semiconductor lasers: review, state-of-the-art, and future developments

    Science.gov (United States)

    Kannengiesser, Christian; Ostroumov, Vasiliy; Pfeufer, Volker; Seelert, Wolf; Simon, Christoph; von Elm, Rüdiger; Zuck, Andreas

    2010-02-01

    Optically Pumped Semiconductor Lasers - OPSLs - have been introduced in 2001. Their unique features such as power scalability and wavelength flexibility, their excellent beam parameters, power stability and reliability opened this pioneering technology access to a wide range of applications such as flow cytometry, confocal microscopy, sequencing, medical diagnosis and therapy, semiconductor inspection, graphic arts, forensic, metrology. This talk will introduce the OPSL principles and compare them with ion, diode and standard solid state lasers. It will revue the first 10 years of this exciting technology, its current state and trends. In particular currently accessible wavelengths and power ranges, frequency doubling, ultra-narrow linewidth possibilities will be discussed. A survey of key applications will be given.

  9. Ten years of R&D and full automation in molecular diagnosis.

    Science.gov (United States)

    Greub, Gilbert; Sahli, Roland; Brouillet, René; Jaton, Katia

    2016-01-01

    A 10-year experience of our automated molecular diagnostic platform that carries out 91 different real-time PCR is described. Progresses and future perspectives in molecular diagnostic microbiology are reviewed: why automation is important; how our platform was implemented; how homemade PCRs were developed; the advantages/disadvantages of homemade PCRs, including the critical aspects of troubleshooting and the need to further reduce the turnaround time for specific samples, at least for defined clinical settings such as emergencies. The future of molecular diagnosis depends on automation, and in a novel perspective, it is time now to fully acknowledge the true contribution of molecular diagnostic and to reconsider the indication for PCR, by also using these tests as first-line assays.

  10. Ten years of Integrated Pest Management (IPM at the Kunsthistorisches Museum in Wien

    Directory of Open Access Journals (Sweden)

    Pascal Querner

    2011-08-01

    Full Text Available The Kunsthistorisches Museum Wien is one of the largest fine arts collections worldwide, comprising the Kunsthistorisches Museum, the Austrian Theater Museum, the Museum of Ethnology, all placed in Vienna, and Schloß Ambras in Tirol. We present results from up to 10 years of insect pest monitoring in different collections and the implementation of an Integrated Pest Management (IPM concept. The Kunsthistorisches Museum was the first museum in Vienna to introduce such a concept. We also present specific insect pest problems such as a biscuit beetle (Stegobium paniceum infestation of paintings lined with starch paste backings (linings or the webbing clothes moth (Tineola bisselliella infestation at the Museum of Carriages, both repeatedly occurring problems in the museum. With the help of the insect pest monitoring programs, these and other problems were found and the infested objects treated, usually with anoxia (nitrogen.

  11. Preliminary ten year results from a randomised single centre mass screening trial for abdominal aortic aneurysm

    DEFF Research Database (Denmark)

    Lindholt, Jes S.; Juul, Svend; Fasting, Helge

    2006-01-01

    to treat" from the date of randomisation. RESULTS: The attendance rate was 76.6% and 191 (4.0%) had an AAA. The median observation time was 9.58 years. In the invited group 13 subjects were acutely operated on compared to 40 in the control group (Risk ratio: 0.32 (95% C.I. 0.17-0.60, P...,333 were invited to an abdominal ultrasound scan at their district hospital. Information on all deaths until 15.3.2005 was obtained from the Office of Civil Registration. Information on AAA related deaths was obtained from the national registry of Causes of Deaths from 1.4.1994 to 31...

  12. [A bibliometrics study of literature on medical image processing for the past ten years].

    Science.gov (United States)

    Chen, Wei; Wang, Yanbin; Ouyang, Zhaolian; Guo, Wenjiao; Chi, Hui

    2014-02-01

    We searched and retrieved literature on the topic of medical image processing published on SCI journals in the past 10 years. We then imported the retrieved literature into TDA for data cleanup before data analysis and pro cessing by EXCLE and UCINET to generate tables and figures that could indicate disciplinary correlation and research hotspots from the perspective of bibliometrics. The results indicated that people in Europe and USA were leading researchers on medical image processing with close international cooperation. Many disciplines contributed to the fast development of medical image processing with intense interdisciplinary researches. The papers that we found show recent research hotspots of the algorithm, system, model, image and segmentation in the field of medical image processing. Cluster analysis on key words of high frequency demonstrated complicated clustering relationship.

  13. MANAGEMENT OF HYPERTHYROIDISM IN CHILDREN AND ADOLESCENTS – TEN YEARS EXPERIENCE

    Directory of Open Access Journals (Sweden)

    Nevenka Bratanič

    2003-03-01

    Full Text Available Background. Graves disease is the most common cause of hyperthyrosis in children and adolescents. The optimal treatment for children with AH remains controversial. The patients are usually treated with antithyroid drugs in combination with thyroxine, followed by definitive treatment with either surgery or radio-iodine if stable remission with antithyroid drug can not be achieved.Patients and methods. Between 1991 and 2000, 45 children (41 girls from 0.5 to 17.5 years were treated at the University Childrens Hospital Ljubljana.Results and conclusions. Fourteen (31.1% patients achieved long-term remission with antithyroid drugs alone. 12 (26.7% of children needed further therapy. Surgery was carried out in 6 (50%, ablation therapy with J131 was successfully used in other six patients.

  14. A quantitative study of TWiki at CERN after ten years of use

    CERN Document Server

    Jones, Peter L

    2016-01-01

    The European Organization for Nuclear Research known as CERN [1], is the home of the Large Hadron Collider (LHC) [2] where physicists are recreating conditions close to those at the origin of the Universe. Although the LHC is based at CERN over 10,000 scientists and engineers from over 100 countries and hundreds of universities and laboratories collaborate on this project. TWiki [3] is an online collaboration platform and was introduced at CERN at the request of the LHC experiments, ALICE, ATLAS, CMS and LHCb have all used TWiki since its introduction. By analyzing the TWiki website statistics from 2006 until April 2016 this paper presents a quantitative study of how TWiki has been put into practice. The results will give a general picture of who is using the system and how this has evolved over the years.

  15. Clinical and paraclinical aspects of children's health ten years after the Chernobyl accident

    International Nuclear Information System (INIS)

    Lukyanova, E.M.; Antipkine, Y.G.; Omelchenko, L.I.; Chernyshov, V.P.; Apuhovskaya, L.I.; Ossinskaya, L.F.

    1997-01-01

    These investigations are devoted to the problem of medical consequences of Chernobyl catastrophe to the children's population of Ukraine. Concerning different reports, Chernobyl accident negatively influenced to the children health indexes. Astonishing fact is that among children under radiation action only 2,1% have no functional deflexions (I group of health) and 28% have chronical diseases with frequent aggravation. Our previous investigation in children evacuated from 30 km zone showed unfavourable changes in immune system. We have shown the data of investigation carried out in the frames of National Program ''Children of Chernobyl''. We have studied the morbidity, some immune functional characteristics and metabolism indexes in 2700 children aged 0-15 years, continually living within radiation contaminated territories. The results were compared with the control indexes, obtained during examination of 980 children from relatively ''clean'' regions. 15 refs, 5 figs, 1 tab

  16. Ten Year Follow-Up of Gap Balanced, Rotating Platform Total Knee Arthroplasty in Patients Under 60 Years of Age.

    Science.gov (United States)

    Lee, Jason H; Barnett, Steven L; Patel, Jay J; Nassif, Nader A; Cummings, Dennis J; Gorab, Robert S

    2016-01-01

    68 patients (91 primary total knee arthroplasties) were evaluated at a mean 10-year, minimum 5 year follow up in patients younger than sixty years of age utilizing the gap balanced, rotating platform design. Follow up assessment included implant survivorship, adverse events, x-rays, Knee Society rating system and clinical evaluation. Three revisions were performed with only one for aseptic loosening at 45 months. Two manipulations were performed in the early postoperative period. Survivorship of the rotating platform, gap balanced knee was 96.7% using surgical revision for any reason and 98.9% using aseptic loosening as endpoints. The rotating platform design using the gap balancing technique in young patients had excellent survivorship at 10-year mean follow up. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Ten-year retrospective follow-up study of the TiOblast dental implant.

    Science.gov (United States)

    Al-Nawas, Bilal; Kämmerer, Peer W; Morbach, Thomas; Ladwein, Catharina; Wegener, Joachim; Wagner, Wilfried

    2012-03-01

    Long-term results in the clinical outcome of different implant systems, including high patient numbers and a long follow-up time, are rare. This retrospective study evaluated the cumulative survival rate of a self-tapping, cylindrical implant system with a conical implant-abutment connection after 10 years of prosthetic loading. A total of 516 TiOblast implants (Astra Tech AB, Mölndal, Sweden) were placed in 108 patients. The patients were treated in the Department of Oral and Maxillofacial Surgery, Johannes Gutenberg University, Mainz, Germany, between September 1994 and May 2005. The main indications for implantation were the treatment of edentulous mandibles (74%) and partial edentulism (15%). Twenty-three implants were placed postradiation, and a further 64 implants were irradiated after insertion. In 153 implants, a bony augmentation was conducted prior to implantation. The in situ rate was 89.7% after an average implantation time of 108 months. Eighty-three patients with 403 implants were available for investigation. Seventeen patients with 76 implants have died since 1994. Absence of osseointegration (n = 22), peri-implantitis (n = 18), fracture of the implants (n = 9), failing of primary stability (n = 2), and implants next to tumors (n = 2) were the reasons of explantation in 26 patients. Under analysis with different implant success-assessment criteria, the success rate showed results from 76 to 89%. With respect to the critical patient selection including a high number of patients with minor and major augmentations, the 10-year clinical use of the studied implant system showed acceptable results. © 2010 Wiley Periodicals, Inc.

  18. The Ross Procedure in Patients among the Pediatric Population, Post Ten Years of Experience

    Directory of Open Access Journals (Sweden)

    Andrey A. Ivanov

    2013-09-01

    Full Text Available The aim of the study was to analyze the results of the surgical treatment in pediatric patients who had undergone the Ross procedure.Material and Methods: The study involved 114 patients between 12 days to 18 years in age. The early and late (up to 5 years results of the treatment were studied. The examination included echocardiography, catheterization of the cardiac chambers and angiocardiography. The case distribution of patients based on diagnosis was as follows: isolated aortic valve stenosis (IAVS in 38 (33.3% patients, aortic valve insufficiency (AVI in 33 (28.9%, and combined heart defects in 56 patients (49.1%.Results: The death rate was 6.14% during the early postoperative period and 1.14% in the late postoperative period; the actuarial survival in the long-term was 98.86%. The complication rate was 51.5%. The most frequent complication was pericarditis (25.6%, whereas cardiac and respiratory failure occurred in 7.6% of the cases and cardiac arrhythmias in 6.1% of the cases. The average time spent in the intensive care unit was 3.48 ± 2.90 days; the hospitalization period on average was 24.70±10.87 days. After surgery, there was a tendency of the echocardiographic parameters to move toward normalization. The frequency of reoperation in the late period was 23.7%, the main reason for which being the conduit dysfunction in the position of the pulmonary artery (PA.Conclusion: The clinical efficacy of the Ross procedure in the treatment of aortic valve malformations in the pediatric group was confirmed. However, in some cases, the need to perform repeated operations due to the increase in the ring size and an increase in the neo-aortic insufficiency during the somatic growth process.

  19. Ten year trend analysis of malaria prevalence in Kola Diba, North Gondar, Northwest Ethiopia

    Directory of Open Access Journals (Sweden)

    Alemu Abebe

    2012-08-01

    Full Text Available Abstract Background Malaria is caused by protozoan parasites of the genus Plasmodium. It is one of the leading causes of illness and death in the world. It is a major public health problem in Ethiopia. Over the past years, the disease has been consistently reported as the first leading cause of outpatient visits, hospitalization and death in health facilities across the country. Methods A retrospective study was conducted to determine the prevalence of malaria from peripheral blood smear examinations from the Kola Diba Health Center of Ethiopia. The case notes of all malaria cases reported between 2002–2011 were carefully reviewed and analyzed. Additionally, any malaria intervention activities that had been taken to control malaria were collected using a well-prepared checklist from the study area. Results Within the last decade (2002–2011 a total of 59, 208 blood films were requested for malaria diagnosis in Kola Diba health center and 23,473 (39.6% microscopically confirmed malaria cases were reported in the town with a fluctuating trend. Regarding the identified plasmodium species, Plasmodium falciparum and Plasmodium vivax accounted for 75% and 25% of malaria morbidity, respectively. Malaria was reported in all age groups and both sexes, but the 15–44 year age group and males were more affected. Despite the apparent fluctuation of malaria trends in the area, the highest peak of malaria cases was reported during spring seasons. Conclusion Comparatively, after the introduction of the current malaria control strategies, the morbidity and mortality by malaria is decreasing but malaria is still a major health problem and the deadly species P. falciparium is predominant. Therefore, control activities should be continued in a strengthened manner in the study area considering both P. falciparium and P. vivax.

  20. Pediatric oral burns: a ten-year review of patient characteristics, etiologies and treatment outcomes.

    Science.gov (United States)

    Cowan, Douglas; Ho, Brian; Sykes, Kevin J; Wei, Julie L

    2013-08-01

    To summarize etiologies and treatments of pediatric oropharyngeal burns. Retrospective summary of 75 patients treated from January 1999 to January 2009. Tertiary Children's Hospital. Data collected included demographics, etiology of burn, site of injury, medical and/or surgical treatments, need for endoscopy, duration of hospitalization, and complications. 75 patients were treated with 50 being males (66%). Mean age was 4.3 years (median 2.7 years). The five most common causes were chemical (34.6%), electrical (12.3%), hot liquids (12.3%), food (12.3%) and battery ingestion (9.9%). Ingestion of hair products made up nearly 1/3 of the chemical causes (9/28) and alone made up 12% of the burns in our study. Main sites of injury included buccal mucosa (77.3%), lips (56%), tongue (48%), and palate (22.7%). One-third of the patients' required PICU/Burn unit admissions, 1/3 were admitted to floor, and 1/3 were discharged home from the ED. Average duration of hospitalization was 5 days. Of those admitted, 30% received antibiotics and only 8% received systemic steroids. Patients were made NPO on the first day of admission in 33.3% of patients and allowed to resume normal diet after surgical consultation. Only 9/75 (12%) patients required intubation. Otolaryngology consultation was obtained in 10.7% of cases. Only 18% of all patients required surgical intervention with debridement being most common (>60%). In this group, 20% received esophagogastroduodenoscopies due to ingestion of alkali substance. Complications occurred in less than 6% of all cases. Ingestion of chemicals, including hair dye/relaxer products, as well as overheated liquids and foods, are leading causes of oropharyngeal burns treated at our Children's Hospital Emergency Department over the past decade. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  1. Etiologic Causes and Epidemiological Characteristics of Patients with Intraocular Foreign Bodies: Retrospective Analysis of 1340 Cases over Ten Years

    Directory of Open Access Journals (Sweden)

    Lin Li

    2018-01-01

    Full Text Available Objective. Patients with intraocular foreign bodies were retrospectively analyzed. Population characteristics, pathogenic factors, and the outcomes during the past ten years were discussed. Design. Retrospective case series study. Method. Medical records of 1340 patients hospitalized in Beijing Tongren Hospital from January 1, 2004, to December 31, 2013, were collected. Results. Average age was 33.0 ± 13.8 (1–76 years old in 1340 patients. There were more males (1270, 94.8% than females (70, 5.2%. Patients from outside of Beijing (82.1%, n=1100 prevailed. Farmers (32.1%, n=430 and workers (22.3%, n=299 were the top two affected professions. Leading two causes were splashing of foreign bodies (SFB (58.6%, n=785 and explosives (31.8%, n=426. More males than females were injured by SFB (59.4% versus 44.3%, P=0.009. Firework injury was the commonest (41.6% versus 3.1%–15.3%, P<0.05 in patients under nine. The annual percentages in patients over 50 increased (P<0.001 and in patients by explosives decreased (P=0.027. Conclusion. Most patients in this study were young males from outside of Beijing and farmers. SFB accounted most for patients over 10 years old and fireworks for those under ten. Patients over 50 increased while those by explosives decreased annually over the period.

  2. Influence of marital status on testosterone levels-A ten year follow-up of 1113 men.

    Science.gov (United States)

    Holmboe, Stine A; Priskorn, Lærke; Jørgensen, Niels; Skakkebaek, Niels E; Linneberg, Allan; Juul, Anders; Andersson, Anna-Maria

    2017-06-01

    Based on a large population of 1113 men aged 30-60 at baseline (mean: 44.1 years, standard deviation: 10.5), we investigated whether intra-individual changes in testosterone (T) and related reproductive hormones during a ten year period were dependent of marital status at baseline and follow-up. The studied men were part of a health survey in Denmark, conducted between 1982 and 1984 with a follow-up examination approximately ten years later. Data on reproductive hormones, measured in serum, and lifestyle and marital status were obtained at both time points. As expected, an age-related decline in testosterone was observed. However, independent of age and lifestyle, we observed that men who went from unmarried to married (n=81) during the study period experienced an accelerated age-related decline in testosterone (-6.6nmol/L) whereas men who went from married to unmarried (n=67) experienced an attenuated age-related decline (-2.3nmol/L). Men who were either married or unmarried at both time points (n=167, n=798, respectively) had a testosterone decline in between (-3.7nmol/L and -4.6nmol/L, respectively). Changes in T/LH ratio did not differ according to marital status indicating that the lowered T level is not compensated by increasing LH levels. This could suggest a modification of the gonadostat due to an adaptation to changing life circumstances. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Lipid profile in adult patients with Fabry disease - Ten-year follow up.

    Science.gov (United States)

    Stepien, Karolina M; Hendriksz, Chris J

    2017-12-01

    Fabry disease, an X-linked genetic condition, results from alpha-galactosidase deficiency and increased accumulation of glycosphingolipids in cardiovascular tissues. Clinical manifestation includes vasculature associated complications. Hyperlipidaemia is one of the cardiovascular risk factors however it has never been well defined in Fabry disease. Enzyme Replacement Therapy (ERT) is available but its effect on serum cholesterol is unknown. The aim of this project was to assess the influence of long-term ERT on lipid profile in a large cohort of adult patients with Fabry disease. This was a retrospective analysis of lipid profile results. Patients with Fabry disease were on ERT for 10 years, were not treated with statins and had no severe renal impairment. All patients had lipid profile measured before ERT was commenced and 6, 12, 24, 36, 48, 60, 120 months later. Statistical analysis included ANOVA, Student t -test and descriptive statistics. Among 72 patients, 40 were females (median age 45; range 29-75), 32 males (median age 46; range 20-69). There was no significant difference in total cholesterol or HDL-cholesterol measured at baseline before ERT was commenced and 6, 12, 24, 36, 48, 60 and 120 months after ERT was commenced in 72 patients (ANOVA; P  = 0.673 and P  = 0.883, respectively). Female patients on ERT had higher mean HDL-cholesterol as compared to female patients with Fabry disease who were asymptomatic and not treated ( P  ≥ 0.05). Total cholesterol between treated and non-treated female patients was comparable. Female patients on ERT have higher total cholesterol and HDL-cholesterol when compared to lipid results in male patients on ERT. Total cholesterol/HDL-cholesterol ratio was low in female and male patients on ERT over 10 years. Adult patients with Fabry disease have remarkably elevated HDL-cholesterol and as a result, elevated total cholesterol. It is possible that elevated HDL-cholesterol has a cardioprotective effect in patients

  4. Ten-Year Follow-Up of Endovascular Aneurysm Treatment with Talent Stent-Grafts

    International Nuclear Information System (INIS)

    Pitton, Michael B.; Scheschkowski, Tobias; Ring, Markus; Herber, Sascha; Oberholzer, Katja; Leicher-Dueber, Annegret; Neufang, Achim; Schmiedt, Walther; Dueber, Christoph

    2009-01-01

    The purpose of this study was to evaluate the clinical results, complications, and secondary interventions during long-term follow-up after endovascular aneurysm repair (EVAR) and to investigate the impact of endoleak sizes on aneurysm shrinkage. From 1997 to March 2007, 127 patients (12 female, 115 male; age, 73.0 ± 7.2 years) with abdominal aortic aneurysms were treated with Talent stent-grafts. Follow-up included clinical visits, contrast-enhanced MDCT, and radiographs at 3, 6, and 12 months and then annually. Results were analyzed with respect to clinical outcome, secondary interventions, endoleak rate and management, and change in aneurysm size. There was no need for primary conversion surgery. Thirty-day mortality was 1.6% (two myocardial infarctions). Procedure-related morbidity was 2.4% (paraplegia, partial infarction of one kidney, and inguinal bleeding requiring surgery). Mean follow-up was 47.7 ± 34.2 months (range, 0-123 months). Thirty-nine patients died during follow-up; three of the deaths were related to aneurysm (aneurysm rupture due to endoleak, n = 1; secondary surgical reintervention n = 2). During follow-up, a total of 29 secondary procedures were performed in 19 patients, including 14 percutaneous procedures (10 patients) and 15 surgical procedures (12 patients), including 4 cases with late conversion to open aortic repair (stent-graft infection, n = 1; migration, endoleak, or endotension, n = 3). Overall mean survival was 84.5 ± 4.7 months. Mean survival and freedom from any event was 66.7 ± 4.5 months. MRI depicted significantly more endoleaks compared to MDCT (23.5% vs. 14.3%; P 10% of the aneurysm area were associated with reduced aneurysm shrinkage compared to no endoleaks or <10% endoleaks (Δ at 3 years, -1.8% vs. -12.0%; P < 0.05). In conclusion, endovascular aneurysm treatment with Talent stent-grafts demonstrated encouraging long-term results with moderate secondary intervention rates. Primary occlusion of all aortic side

  5. Ectopic pregnancy management in Ayub Teaching Hospital Abbottabad: a ten year survey.

    Science.gov (United States)

    Deeba, Farhat; Khan, Bushra; Khattak, Samina Naseem

    2012-01-01

    Ectopic pregnancy is a common life-threatening emergency in the developing world. It is a cause of maternal morbidity and mortality in the first trimester and these mortalities can be reduced if it is properly managed. The objective of this study was to assess the variable clinical presentations and outcome of treatment of ectopic pregnancy in Ayub Teaching Hospital Abbottabad. Two hundred and fifty-five patients with ectopic pregnancy managed in Ayub Teaching Hospital over period of 10 years, were included in the study. The clinical presentation, diagnostic modalities and out come of treatment were recorded and analysed. Out of 255 patients 43 (16.86%) had un-ruptured tubal pregnancy, 183 (71.76%) had ruptured ectopic pregnancy and 22 (8.62%) had chronic ectopic pregnancy. At laparotomy, salpingectomy was done in 229 (89.80%) patients, salpingo-ophrectomy in 2 patients (0.78%), linear salpingostomy in 15 (5.88%) patients. Medical treatment was given to 5 patients and 8 patients were treated conservatively. There was no maternal mortality. In spite of various recent advances in the management of ectopic pregnancy, conventional surgical treatment by laparotomy is still the most widely used modality of treatment in our institution. With appropriate and prompt management, maternal mortality due to ectopic pregnancy can be prevented.

  6. [Ten years after German unification--current behavioural and emotional problems of adolescents in Germany].

    Science.gov (United States)

    von Widdern, Susanne; Hässler, Frank; von Widdern, Olrik; Richter, Jörg

    2004-11-01

    Internalizing and externalizing problems based on Youth Self-Report (YSR) were investigated in an empirical sample of 371 students at the age of 13 until 18 years from common secondary and vocational schools in Rostock (Mecklenburg-Western Pomerania) in 2000/2001. Considering syndromes in comparison with other german and international empirical studies, internalizing and externalizing problems show high prevalence for both girls and boys. Nearly every fifth student judges themselves as within clinical range for psychiatric problems. Girls reported significant more internalizing problems (social withdrawal, somatic complaints, anxious/depressed). An interaction effect by age and sex for aggressive and delinquent behaviour was found with highest prevalence for boys at age 15/16. The frequency of internalizing problems and attention problems increases with adolescent's age. Low adolescent's education level, parental divorce and big size of siblings were associated with externalizing problems, whereas unemployment of the father was associated with depressive and social problems. Delinquent behaviour and attention problems are the most important predictors for negative school outcome like comparatively bad school achievement and low reading ability. The results suppose a possible increase in psychosocial problems of juvenile persons in eastern Germany one decade after German Unification, indicated the necessity of higher supply for preventive and therapeutic programs.

  7. Gender, internet experience, Internet identification, and internet anxiety: a ten-year followup.

    Science.gov (United States)

    Joiner, Richard; Gavin, Jeff; Brosnan, Mark; Cromby, John; Gregory, Helen; Guiller, Jane; Maras, Pam; Moon, Amy

    2012-07-01

    In 2002, we found gender differences in the use of the Internet. Since then, however, the Internet has changed considerably. We therefore conducted a follow-up study in 2012. The study involved 501 students (389 females and 100 males, 12 participants unspecified gender) and we measured Internet use, Internet anxiety, and Internet identification. We found that males had a greater breadth of Internet use; they used the Internet more for games and entertainment than females. The differentiation between males and females in terms of Internet use is evident, and in some ways is even more distinct than 10 years ago. In our previous research we had found no gender differences in the use of the Internet for communication, whereas in the current study we have found that females use the Internet for communication than males and were using social network sites more than males. We also found, consistent with our previous study, that Internet identification and Internet anxiety were related to Internet use.

  8. Ten Years of Land Cover Change on the California Coast Detected using Landsat Satellite Image Analysis

    Science.gov (United States)

    Potter, Christopher S.

    2013-01-01

    Landsat satellite imagery was analyzed to generate a detailed record of 10 years of vegetation disturbance and regrowth for Pacific coastal areas of Marin and San Francisco Counties. The Landsat Ecosystem Disturbance Adaptive Processing System (LEDAPS) methodology, a transformation of Tasseled-Cap data space, was applied to detected changes in perennial coastal shrubland, woodland, and forest cover from 1999 to 2009. Results showed several principal points of interest, within which extensive contiguous areas of similar LEDAPS vegetation change (either disturbed or restored) were detected. Regrowth areas were delineated as burned forest areas in the Point Reyes National Seashore (PRNS) from the 1995 Vision Fire. LEDAPS-detected disturbance patterns on Inverness Ridge, PRNS in areas observed with dieback of tanoak and bay laurel trees was consistent with defoliation by sudden oak death (Phytophthora ramorum). LEDAPS regrowth pixels were detected over much of the predominantly grassland/herbaceous cover of the Olema Valley ranchland near PRNS. Extensive restoration of perennial vegetation cover on Crissy Field, Baker Beach and Lobos Creek dunes in San Francisco was identified. Based on these examples, the LEDAPS methodology will be capable of fulfilling much of the need for continual, low-cost monitoring of emerging changes to coastal ecosystems.

  9. Ten years of implementing screening, brief intervention, and referral to treatment (SBIRT): Lessons learned.

    Science.gov (United States)

    Nunes, Ana P; Richmond, Melissa K; Marzano, Kelly; Swenson, Carolyn J; Lockhart, Jodi

    2017-01-01

    The US Surgeon General recently issued a comprehensive report indicating that substance use is a major public health concern that must be addressed using a number of strategies. Screening, brief intervention, and referral to treatment (SBIRT) is one such strategy. SBIRT Colorado, funded by the Substance Abuse and Mental Health Services Administration (SAMHSA), has implemented a statewide initiative for the past 10 years that has provided ample opportunities to identify key components for successful implementation. Successful implementation requires (1) strong clinical and management advocates; (2) full integration of services into practices' workflow utilizing technology whenever possible; (3) interprofessional team approaches; (4) appropriate options for the small proportion of patients screening positive for a possible substance use disorder; (5) cannabis screening that accounts for legalization, and interventions that acknowledge differences between alcohol and cannabis use; (6) incorporating SBIRT into standard health care professionals' training; and (7) addressing the significant issues regarding reimbursement through private and public payers for SBIRT services. Implementing and sustaining SBI as a standard of integrated care is essential to reduce the burden of substance use. Interdisciplinary approaches, technology, and training to increase practitioner confidence and skill are fundamental.

  10. Ten years of maintaining and expanding a microbial genome and metagenome analysis system.

    Science.gov (United States)

    Markowitz, Victor M; Chen, I-Min A; Chu, Ken; Pati, Amrita; Ivanova, Natalia N; Kyrpides, Nikos C

    2015-11-01

    Launched in March 2005, the Integrated Microbial Genomes (IMG) system is a comprehensive data management system that supports multidimensional comparative analysis of genomic data. At the core of the IMG system is a data warehouse that contains genome and metagenome datasets sequenced at the Joint Genome Institute or provided by scientific users, as well as public genome datasets available at the National Center for Biotechnology Information Genbank sequence data archive. Genomes and metagenome datasets are processed using IMG's microbial genome and metagenome sequence data processing pipelines and are integrated into the data warehouse using IMG's data integration toolkits. Microbial genome and metagenome application specific data marts and user interfaces provide access to different subsets of IMG's data and analysis toolkits. This review article revisits IMG's original aims, highlights key milestones reached by the system during the past 10 years, and discusses the main challenges faced by a rapidly expanding system, in particular the complexity of maintaining such a system in an academic setting with limited budgets and computing and data management infrastructure. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Ten years of transcriptomics in wild populations: what have we learned about their ecology and evolution?

    Science.gov (United States)

    Alvarez, Mariano; Schrey, Aaron W; Richards, Christina L

    2015-02-01

    Molecular ecology has moved beyond the use of a relatively small number of markers, often noncoding, and it is now possible to use whole-genome measures of gene expression with microarrays and RNAseq (i.e. transcriptomics) to capture molecular response to environmental challenges. While transcriptome studies are shedding light on the mechanistic basis of traits as complex as personality or physiological response to catastrophic events, these approaches are still challenging because of the required technical expertise, difficulties with analysis and cost. Still, we found that in the last 10 years, 575 studies used microarrays or RNAseq in ecology. These studies broadly address three questions that reflect the progression of the field: (i) How much variation in gene expression is there and how is it structured? (ii) How do environmental stimuli affect gene expression? (iii) How does gene expression affect phenotype? We discuss technical aspects of RNAseq and microarray technology, and a framework that leverages the advantages of both. Further, we highlight future directions of research, particularly related to moving beyond correlation and the development of additional annotation resources. Measuring gene expression across an array of taxa in ecological settings promises to enrich our understanding of ecology and genome function. © 2015 John Wiley & Sons Ltd.

  12. Ten years of preanalytical monitoring and control: Synthetic Balanced Score Card Indicator

    Science.gov (United States)

    López-Garrigós, Maite; Flores, Emilio; Santo-Quiles, Ana; Gutierrez, Mercedes; Lugo, Javier; Lillo, Rosa; Leiva-Salinas, Carlos

    2015-01-01

    Introduction Preanalytical control and monitoring continue to be an important issue for clinical laboratory professionals. The aim of the study was to evaluate a monitoring system of preanalytical errors regarding not suitable samples for analysis, based on different indicators; to compare such indicators in different phlebotomy centres; and finally to evaluate a single synthetic preanalytical indicator that may be included in the balanced scorecard management system (BSC). Materials and methods We collected individual and global preanalytical errors in haematology, coagulation, chemistry, and urine samples analysis. We also analyzed a synthetic indicator that represents the sum of all types of preanalytical errors, expressed in a sigma level. We studied the evolution of those indicators over time and compared indicator results by way of the comparison of proportions and Chi-square. Results There was a decrease in the number of errors along the years (P errors occurred in outpatients, followed by inpatients. Conclusion We present a practical and effective methodology to monitor unsuitable sample preanalytical errors. The synthetic indicator results summarize overall preanalytical sample errors, and can be used as part of BSC management system. PMID:25672466

  13. Ten Year Analysis of Tropopause-Overshooting Convection Using GridRad Data

    Science.gov (United States)

    Cooney, John W.; Bowman, Kenneth P.; Homeyer, Cameron R.; Fenske, Tyler M.

    2018-01-01

    Convection that penetrates the tropopause (overshooting convection) rapidly transports air from the lower troposphere to the lower stratosphere, potentially mixing air between the two layers. This exchange of air can have a substantial impact on the composition, radiation, and chemistry of the upper troposphere and lower stratosphere (UTLS). In order to improve our understanding of the role convection plays in the transport of trace gases across the tropopause, this study presents a 10 year analysis of overshooting convection for the eastern two thirds of the contiguous United States for March through August of 2004 to 2013 based on radar observations. Echo top altitudes are estimated at hourly intervals using high-resolution, three-dimensional, gridded, radar reflectivity fields created by merging observations from available radars in the National Oceanic and Atmospheric Administration Next Generation Weather Radar (NEXRAD) network. Overshooting convection is identified by comparing echo top altitudes with tropopause altitudes derived from the ERA-Interim reanalysis. It is found that overshooting convection is most common in the central United States, with a weak secondary maximum along the southeast coast. The maximum number of overshooting events occur consistently between 2200 and 0200 UTC. Most overshooting events occur in May, June, and July when convection is deepest and the tropopause altitude is relatively low. Approximately 45% of the analyzed overshooting events (those with echo tops at least 1 km above the tropopause) have echo tops extending above the 380 K level into the stratospheric overworld.

  14. Report on equipment availability for the ten-year period, 1966--1975

    Energy Technology Data Exchange (ETDEWEB)

    1976-12-01

    This is an annual report of availability and outage statistics for electric power generating facilities operating in the United States. A list of utility organizations voluntarily participating in the EEI Equipment Availability Program in 1975 is located in Appendix F. All summary reports in this publication are for the 10-year period 1966-1975. Each reporting utility company has received reports on individual units for which data were submitted. Also, selected major equipment manufacturers receive copies of computer reports showing an analysis of the data for their equipment. Revised reporting instructions to incorporate Safety and Environmental Requirement Cause Codes were issued effective January 1, 1976. In addition, provisions were made for identifying major equipment manufactured outisde of the United States or under foreign license. Recognizing that an Annual Report contains only a limited amount of general outage data in selected categories, the Task Force has agreed to perform special analyses of the data bank if the cost of computer services is met by the requestor and if the required analysis conforms to some designated policy guidelines.

  15. Head and neck lymphomas – a retrospective ten-year observation

    Science.gov (United States)

    Stryjewska-Makuch, Grażyna; Janik, Małgorzata; Kolebacz, Bogdan; Lisowska, Grażyna; Ścierski, Wojciech

    2017-01-01

    Aim of the study Lymphomas are a heterogeneous group of tumours of lymphoid tissue in which there is an abnormal proliferation of cells of the lymphatic system. The literature notes a gradual increase in the incidence of this type of cancer in the whole population. The aim of the study was to evaluate whether the above tendency occurs in the head and neck area. Material and methods In the years 2005–2014, at the Otolaryngology and Laryngological Oncology Department of the Upper Silesian Medical Centre in Katowice, 77 cases of lymphoma were recorded, 58 of which were analysed in terms of location, histological type, age and sex of the patient, and the presence of risk factors. Results The vast majority of them were non-Hodgkin’s lymphomas (NHL) – 67.53%. Hodgkin’s lymphomas (HL) accounted for only a small fraction of diagnoses (7.79%). In terms of histopathological types, in most cases of NHL, there occurred diffuse large B-cell lymphomas (DLBCL) – 51.92%. The most common location was the lymph nodes, representing the location of the primary lesion in more than half of the cases. As regards the extranodal location, the Waldeyer ring dominated (54.54%) along with the palatal tonsil (40.90%). There has been a significant upward trend, especially in the incidence of NHL. PMID:28435401

  16. Ten years of preanalytical monitoring and control: Synthetic Balanced Score Card Indicator.

    Science.gov (United States)

    Salinas, Maria; López-Garrigós, Maite; Flores, Emilio; Santo-Quiles, Ana; Gutierrez, Mercedes; Lugo, Javier; Lillo, Rosa; Leiva-Salinas, Carlos

    2015-01-01

    Preanalytical control and monitoring continue to be an important issue for clinical laboratory professionals. The aim of the study was to evaluate a monitoring system of preanalytical errors regarding not suitable samples for analysis, based on different indicators; to compare such indicators in different phlebotomy centres; and finally to evaluate a single synthetic preanalytical indicator that may be included in the balanced scorecard management system (BSC). We collected individual and global preanalytical errors in haematology, coagulation, chemistry, and urine samples analysis. We also analyzed a synthetic indicator that represents the sum of all types of preanalytical errors, expressed in a sigma level. We studied the evolution of those indicators over time and compared indicator results by way of the comparison of proportions and Chi-square. There was a decrease in the number of errors along the years (P<0.001). This pattern was confirmed in primary care patients, inpatients and outpatients. In blood samples, fewer errors occurred in outpatients, followed by inpatients. We present a practical and effective methodology to monitor unsuitable sample preanalytical errors. The synthetic indicator results summarize overall preanalytical sample errors, and can be used as part of BSC management system.

  17. Ten years of Italian historiography of psychology: a field in progress.

    Science.gov (United States)

    Ceccarelli, Glauco; Cimino, Guido; Foschi, Renato

    2010-08-01

    This article briefly outlines a picture of the activities and research conducted in Italy on the history of psychology during the last 10 years, focusing its attention on institutions, scholars, conferences, archives, journals, and so forth. At the dawn of the 21st century, the tradition of historical-psychological studies that developed in the last quarter of the 20th century has led to a renewed situation in teaching organization and research, with the emergence of several groups, especially at the universities of Rome "Sapienza", Bari, Milan-Bicocca, and Urbino, and of a second generation of young historians increasingly engaged on an international level. After a general survey conducted with historiometric method on the principal areas of research cultivated and on the themes dealt with, we mention a change that has occurred in the historiographical approach, a transition from a historiography addressed prevalently to the "history of ideas" to one that, pursuing the approach of a new and critical "multifactorial" history, proves to be more attentive to the social and institutional history, in correspondence with established international trends.

  18. Ten-year Survivors After Contemporary Management of Advanced 'Horseshoe' Anterior Commissure Laryngeal Cancer.

    Science.gov (United States)

    Ampil, Federico; Caldito, Gloria; Vora, Moiz; Richards, Troy

    2016-06-01

    Combinations of treatment modalities for locally extensive carcinomas of the larynx constitute the standard of care. Advanced 'horseshoe' anterior commissure laryngeal cancer (HACLC) is a disease entity that has not received much attention in the literature. The aims of this study were to evaluate prolonged survival in patients after standard combined therapy for HACLC and to identify clinicopathological factors influential towards an extended outcome. Fourteen patients (10-year survivors) with stage III or IV laryngeal cancer involving the anterior commissure and both true vocal cords were treated with total laryngectomy (and postoperative radiotherapy in 11 individuals). During follow-up, ranging from 123 to 256 months, locoregional recurrent disease and distant metastasis were not observed. Complications after therapy were manageable and few. The long-term survivors were particularly difficult to characterize. The optimal treatment for advanced HACLC has not been clarified; however, in this study, total laryngectomy and the indicated use of postoperative radiotherapy, were successful in achieving long-term disease-free survival. Predictive factors for longevity were not detected in this limited experience. Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

  19. LECA refurbishment project or how to get ready for the next ten years

    Energy Technology Data Exchange (ETDEWEB)

    Boussard, Francois; Bois, Dominique; Blanc, Jean Yves

    2005-01-01

    Around 1995, CEA decided a strategy for its hot laboratories: Closing LAMA - Grenoble and LHA - Saclay, after RM2 - Fontenay-aux-Roses. Refurbishing and gathering irradiated material studies in LECI - Saclay. Refurbishing LECA - Cadarache for irradiated fuel examinations. Reprocessing pilot experiments being located in Atalante - Marcoule. Started up in 1964, LECA has got an exploitation license up to August 2005. In 2001, safety authorities agreed to extend it up to 2015, provided an extensive refurbishment is undertaken which includes civil engineering works to achieve the building earthquake resistance, based on 3D-computations and withstanding maximum historically likely earthquake, improving confinement by decontaminating, adding steel boxes inside cells, changing ventilation system and creating a mobile upper cell on the cell roof, changing power supplies, shielded glasses and most manipulators, improving travelling crane, fire protection, radioactivity monitoring and alarms, installing a new device for characterizing and evacuating wastes, decreasing the fissile mass stored inside the facility (source term). Most of the work should be ended by the end of 2005. Afterwards five cells, which do not withstand earthquake, will be deconstructed within 3 years. By mid 2004, 60 % of tasks are completed and all contracts are awarded. The total final cost is 97 M Euro, 80% of which regarding the only LECA refurbishment. (Author)

  20. Ten years after: is it time to revisit the 1994 OSHA indoor air quality rule?

    Science.gov (United States)

    Ahrens, David

    2011-01-01

    Approximately 20 million nonsmoking workers are employed in workplaces without restrictions on smoking and are potentially exposed to secondhand smoke--a Class A carcinogen. These workers are largely in the service industry, in southern and western states and in non-urban areas. The Occupational Safety and Health Administration's (OSHA's) 1994 proposal for smoke-free workplaces (withdrawn in 2001) was attacked by many interest groups that may no longer oppose this protection. Federal regulation for smoke-free workplaces is needed for workers, who are not protected by state and local smoke-free laws. This policy could save thousands of lives each year, and prevent significant illness. Twenty-one states have "state plans" that would allow more protective laws. Of the 29 states under OSHA, 11 have comprehensive smoke-free statutes. Changes in the policy environment and in institutions such as unions, restaurant associations, and the tobacco industry since 2001 may improve the prospects for federal action and reduce disparities that currently characterize exposure to secondhand smoke.

  1. Acute cerebellitis in varicella: a ten year case series and systematic review of the literature.

    Science.gov (United States)

    Bozzola, Elena; Bozzola, Mauro; Tozzi, Alberto Eugenio; Calcaterra, Valeria; Longo, Daniela; Krzystofiak, Andrzej; Villani, Alberto

    2014-06-19

    Acute cerebellitis (AC) is the most common neurological complication of varicella. Nevertheless, it has been scarcely studied. The objective of this study were to asses the occurrence of AC among children hospitalized for varicella and to analyze its specific clinical picture and outcome. We retrospectively reviewed the medical records of children admitted to the hospital for varicella between 1st October 2003 and 1st June 2013 and we compared our results with literature. Children were all unvaccinated for varicella. In our case series, AC was found out in 48 out of 457 patients (10.5%). The highest frequency of AC was observed in children from 1 to 5 years of age (60.9%). The most characteristic symptom of AC was a broad-based gait disturbance that progressed gradually over the course of a few days (95.8%). Other common symptoms included slurred speech (37.5%), vomiting (31.25%), headache (29.16%), dysmetry (25%) and tremor (22.91%). After a long hospitalization (median of 11 days), all but one children were dismissed without invalidating sequelae. Data from this study may help to better address the problem of varicella cerebellar complications in hospitalized children and to monitor changes over time caused by an increase in vaccination coverage.

  2. [Ten years of HIV-AIDS epidemic in more than 60 years in Federal District--Brazil].

    Science.gov (United States)

    Oliveira, Maria Liz Cunha de; Paz, Leidijany Costa; Melo, Gislane Ferreira de

    2013-03-01

    The progressive increase in number of HIV/AIDS cases in old age brings the necessity of studies about the specificities of this phenomenon by region. To identify the epidemiology in AIDS cases diagnosed in Distrito Federal - Brasil, in individuals aged > 60 years old. We conducted a time serie study with secondary data from SINAN/AIDS for the period January 1999 to December 2009. In this period, 4,258 new cases of AIDS were of whom 89 (2.0%) are elderly. Although a small percentage, the annual growth was continuous. The most frequent exposure category was heterosexual, the age group most affected was 60 and 69 years, with 71 (79.8%) cases; the proportion of cases man/woman has changed over the years, in 1999 was 1:1 and in 2006, 0,7:1. The HIV/AIDS epidemic among the elderly can be seen stable on the Distrito Federal.

  3. Pelvic exenteration: ten-year experience at the European Institute of Oncology in Milan.

    Science.gov (United States)

    Maggioni, Angelo; Roviglione, Giovanni; Landoni, Fabio; Zanagnolo, Vanna; Peiretti, Michele; Colombo, Nicoletta; Bocciolone, Luca; Biffi, Roberto; Minig, Lucas; Morrow, C Paul

    2009-07-01

    Analyze morbidity and survival after pelvic exenteration (PE) of gynecological malignancies. We reviewed 106 consecutive patients with gynecologic malignancies who underwent PE from June 1996 to April 2007 at the Division of Gynecology, European Institute of Oncology (IEO), Milan. PE was performed for cancer of the cervix (62 patients), vagina (21 patients), vulva (9 patients), endometrium (9 patients), ovary (4 patients) and 1 uterine sarcoma. Mean age was 53.6 (30-78) years. 97% of the patients received radiotherapy before PE and 3 patients had PE as primary treatment. We performed 53 anterior, 48 total and 5 posterior PE. Median operation time, estimated blood loss and hospital stay were respectively 490 (200-780) minutes, 1240 (300-6500) ml and 21.6 (11-55) days. No residual tumor was left in 93% of the patients. Median follow-up was 22.3 (1.6-117) months. There were no post-operative deaths (<30 days from surgery) nor intra-operative mortality. Total morbidity rate was 66%; 48% of patients had early complications (<30 days after PE) whereas 52 patients (48.5%) had late complications; 70% of these occurred to the urinary tract and 25% were due to bowel occlusions or fistulas. Overall survival was 52%, 35%, 19% and 16% respectively for cervical, endometrial, vaginal and vulvar cancer. PE is a feasible technique with no post-operative mortality and high percentage of long-survivors, although the morbidity rate still remains significantly high. Careful patient selection, pre- and post-operative care and optimal surgical skills in a Gynecologic Oncologic Center are the cornerstones to further improve quality of life and survival for these patients.

  4. Video-Teleconferencing in Pediatric Neuro-Oncology: Ten Years of Experience

    Directory of Open Access Journals (Sweden)

    Nisreen Amayiri

    2017-04-01

    Full Text Available Purpose: The management of central nervous system tumors is challenging in low- and middle-income countries. Little is known about applicability of twinning initiatives with high-income countries in neuro-oncology. In 2004, a monthly neuro-oncology video-teleconference program was started between King Hussein Cancer Center (Amman, Jordan and the Hospital for Sick Children (Toronto, Ontario, Canada. More than 100 conferences were held and > 400 cases were discussed. The aim of this work was to assess the sustainability of such an initiative and the evolution of the impact over time. Methods: We divided the duration in to three eras according to the initial 2 to 3 years of work of three consecutive oncologists in charge of the neuro-oncology program at King Hussein Cancer Center. We retrospectively reviewed the written minutes and compared the preconference suggested plans with the postconference recommendations. Impact of changes on the patient care was recorded. Results: Thirty-three sets of written minutes (covering 161 cases in the middle era and 32 sets of written minutes (covering 122 cases in the last era were compared with the initial experience (20 meetings, 72 cases. Running costs of these conferences has dropped from $360/h to < $40/h. Important concepts were introduced, such as multidisciplinary teamwork, second-look surgery, and early referral. Suggestions for plan changes have decreased from 44% to 30% and 24% in the respective consecutive eras. Most recommendations involved alternative intervention modalities or pathology review. Most of these recommendations were followed. Conclusion: Video-teleconferencing in neuro-oncology is feasible and sustainable. With time, team experience is built while the percentage and the type of treatment modifications change. Commitment and motivation helped maintain this initiative rather than availability of financial resources. Improvement in patients’ care was achieved, in particular, with the

  5. Ten-year experience in management of diabetic ketoacidosis and ketosis: 140 episodes at pediatric age.

    Science.gov (United States)

    Yordam, Nuren; Gönç, E Nazli; Kandemir, Nurgün; Alikaşifoğlu, Ayfer; Ozön, Alev

    2005-01-01

    One hundred and forty episodes in 112 patients (58 boys) with diabetic ketoacidosis (96 episodes) and diabetic ketosis (44 episodes) were studied to elucidate the clinical and laboratory risk factors for altered level of consciousness at presentation and to analyze the outcome of a distinct protocol in the treatment of diabetic ketoacidosis. The patients were analyzed according to demographic data and clinical and laboratory findings at admission. The treatment protocol involved use of 0.45% sodium chloride (NaCl) in 2.5% dextrose as the initial fluid therapy following volume expansion. Dextrose content of the fluid was doubled once the serum glucose level fell below 250 mg/dl. The mean ages at presentation with diabetic ketoacidosis and ketosis were 10.3 +/- 4.4 and 10.2 +/- 4.0 years, respectively. Thirty-one percent of patients had altered consciousness at presentation. The level of consciousness correlated negatively with serum bicarbonate level (r=-0.485; p<0.001). A serum bicarbonate level below 15 mmol/L was a risk factor for altered consciousness. There was no correlation between effective osmolality and the level of consciousness. Serum effective osmolality above 320 mOsm/kg H2O did not appear to be a risk factor for altered consciousness. No mortality or any signs of clinical brain edema were observed in patients treated with the distinct treatment protocol. In conclusion, acidosis appears to be the major factor in the pathogenesis of altered consciousness at presentation. Serum effective osmolality does not seem to be a risk factor as suggested previously. Dextrose added to the infusion fluid early in treatment seems to prevent the development of brain edema, and this may be due to a protective effect of higher osmolality in the resultant solution.

  6. Acute health problems in African refugees: ten years' experience in a Swiss emergency department.

    Science.gov (United States)

    Pfortmueller, Carmen A; Graf, Fabienne; Tabbara, Malek; Tabarra, Malek; Lindner, Gregor; Zimmermann, Heinz; Exadaktylos, Aristomenis K

    2012-09-01

    Over the last two decades, the total number of applications from Africans for asylum in the countries of the European Union has increased from 578,000 to more than 2.9 million. About 20 % (7,196/36,100) of the asylum seekers in Switzerland originate from Africa. The disease profile of African asylum seekers is remarkably different from that of the native population in the country of application. We have therefore conducted an analysis of African asylum seekers presenting themselves to our emergency department. In a retrospective analysis, the central patient registry database was searched for patients originating from Africa admitted from 1 January 2000 to 30 November 2011 and labelled as "Asylbewerber" (asylum seeker) or "Flüchtling" (refugee). Three thousand six hundred and seventy-five African asylum seekers were admitted to our emergency department between 2000 and 2010. Thirty-four percent (n = 1,247) were female and 66 % (n = 2,426) male. Eighty percent (n = 1,940) of the men and 70 % (n = 823) of the women were younger than 40 years. Most of our patients originated from Algeria (n = 612). Forty-five percent (n = 1,628) of all patients presented with internal medical problems, 40 % (n = 1,487) with injuries. 3.5 % (n = 130) of all patients presented with psychiatric problems. Admission for psychiatric problems increased steadily from 2 % (n = 4) in 2001 to 10 % (n = 35) in 2011. The causes of presentation are manifold, including internal medical problems and injuries. Admissions for psychiatric problems are increasing. Establishing simple screening scores for somatization should be a key priority in providing more focused treatment in emergency departments.

  7. Visual disability rates in a ten-year cohort of patients with anterior visual pathway meningiomas.

    Science.gov (United States)

    Bor-Shavit, Elite; Hammel, Naama; Nahum, Yoav; Rappaport, Zvi Harry; Stiebel-Kalish, Hadas

    2015-01-01

    To examine the visual outcome of anterior visual pathway meningioma (AVPM) patients followed for at least one year. Data were collected on demographics, clinical course and management. Visual disability was classified at the first and last examination as follows: I--no visual disability; II--mild visual defect in one eye; III--mild visual defect in both eyes; IV--loss of driver's license; V--legally blind. Eight-one AVPM patients had their tumor originate in the clinoid process in 23 (28%), sphenoid-wing area in 18 (22%), cavernous sinus in 15 (19%), tuberculum sellae in 8 (10%), and mixed in 17 (21%). On last examination, 46 patients (57%) had good visual acuity in one or both eyes (Class I or II) and 17 (21%) were mildly affected in both eyes. The rate of Class IV disability was 16%, and Class V disability was 6%. Attention needs to be addressed to the considerable proportion of patients with AVPM (22% in this study) who may lose their driver's license or become legally blind. Occupational therapists should play an important role in the multidisciplinary management of those patients to help them adapt to their new physical and social situation. Anterior visual pathway meningiomas (AVPMs) are commonly not life-threatening but they can lead to profound visual disability, especially when the tumor originates in the tuberculum sellae and cavernous sinus. Particular attention should be paid to visual acuity and visual field deficits, as these can profoundly affect the patient's quality of life including ability to drive and activities of daily living. The interdisciplinary management of patients with AVPM should include the neurosurgeon, neuro-ophthalmologist and occupational therapist. Also, early intervention by the occupational therapist can help patients adapt to their current physical and social situation and return to everyday tasks more rapidly.

  8. Ten Years of Equine-related Injuries: Severity and Implications for Emergency Physicians.

    Science.gov (United States)

    Davidson, Scott B; Blostein, Paul A; Schrotenboer, Andrew; Sloffer, Chris A; VandenBerg, Sheri L

    2015-11-01

    The size, speed, and unpredictable nature of horses present a significant risk for injury in all equine-related activities. We sought to examine the mechanism, severity, frequency, body regions affected, surgical requirements, rehabilitation needs, safety equipment utilization, and outcomes of equine-related injured patients. Records of inpatients who sustained an equine-related injury from 2002-2011 with International Classification of Diseases, Ninth Revision codes E828 and E906 were retrospectively reviewed for pertinent data. Ninety patients, 70% female, age (mean ± SD) 37.3 ± 19.4 years, length of stay 3.7 ± 4.5 days, Injury Severity Score 12.9 ± 8.4. Predominant mechanism of injury was fall from horse (46.7%). The chest (23%) was most frequently injured, followed by brain/head (21.5%). Thirty patients (33%) required 57 surgical procedures. Twenty percent of patients required occupational therapy and 33.3% required physical therapy while hospitalized. Only 3% required rehabilitation, with 90% discharged directly home. Safety equipment was not used in 91.9% of patients. One patient sustained a cord injury. Six patients expired, all from extensive head injuries. The majority of equine-related injuries occur while pursuing recreational activities and are due to falls. Our patients experienced more severe injuries to the trunk and head and required more surgical intervention for pelvic, facial, and brain injuries than previously reported. Failure to use safety equipment contributes to the risk of severe injury. Education and injury prevention is essential. The need for complex surgical intervention by multiple specialties supports transfer to Level I trauma centers. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. Henoch-Schönlein purpura outcome in children: A ten-year clinical study

    Directory of Open Access Journals (Sweden)

    Spasojević-Dimitrijeva Brankica

    2011-01-01

    Full Text Available Introduction. Henoch-Schönlein purpura (HSP is the most common vasculitis of childhood. It is characterized by symptoms including nonthrombocytopenic purpura, abdominal pain, haematuria/proteinuria, and arthralgia/arthritis. The pleiomorphism of clinical signs in HSP could be confused with other conditions or other vasculitis forms. Objective. Evaluation of HSP clinical presentation, the onset and severity of renal manifestation in affected children and their outcome. Methods. A retrospective study of 49 patients diagnosed with HSP was conducted from September 1999 to September 2009. Children with severe renal manifestations (nephrotic range proteinuria, with or without nephrotic or nephritic syndrome have undergone kidney biopsy. Results. Twenty-five patients developed renal manifestations after onset of the disease. In our study child’s older age was a risk factor for association with HSP nephritis. Six of the patients required kidney biopsy. They were successfully treated with various immunosuppressive protocols, as well as three of nine patients with nephrotic range proteinuria. Two patients developed most severe form of HSP nephritis, nephrotic-nephritic syndrome with histology grade IIIb/IVb. During the study period (average follow-up 6 years, all patients had a normal global renal function with mild proteinuria in only two cases. The prognosis of renal involvement was better than reports from other patient series. Conclusion. Long-term morbidity of HSP is predominantly attributed to renal involvement. During the study period, no patient had renal insufficiency or end stage renal disease after various combinations of immunosuppressive treatment. It is recommended that patients with HSP nephritis are followed for longer periods of time with a regular measurement of renal function and proteinuria.

  10. Pre-natal diagnosis of thalassaemia in Sri Lanka: A ten year review.

    Science.gov (United States)

    Nanayakkara, Kalinga Khemal; Rodrigo, Undugodage Ganganath; Perera, Kuda Liyanage Nandika; Nanayakkara, Chinthani Deepthi

    2017-10-01

    Thalassaemia is the commonest monogenic disease in Sri Lanka, affecting over 3500 children and half-a-million thalassaemia carriers. This is a review of 82 amniocenteses performed from 2006 to 2016, in the largest prenatal diagnoses study for thalassaemia carried out in Sri Lanka. Amniocenteses were performed between 11 and 12 weeks of ultrasonically confirmed gestation, on mothers with previous thalassaemia major children pregnant for the second time and nulliparous thalassaemia trait women married to trait partners. The Consultant Radiologist, using local analgesia, under ultrasound cover, performed these as an outpatient procedure, at the Teaching Hospital Kandy & Suwasevana Hospital Kandy. The amniotic fluid was analysed by the team of Senior Geneticists, at the Genetech Molecular Diagnostics and School of Gene Technology, Colombo, via the polymerase-chain-reaction based ARMS (Amplification Refractory Mutation Systems) assay. The genetic results indicated the presence of 21% thalassaemia major foetuses, 53% thalassaemia traits and 26% foetuses without thalassaemia mutations. The predominance of the IVS1-5(G-C) mutation in the Sri Lankan population is exemplified, with a low prevalence of HbE thalassaemia. Impact statement Thalassaemia is the commonest monogenic disease in Sri Lanka affecting over 3500 children and half-a-million thalassaemia carriers. Although pre-natal diagnosis by amniocentesis was practised universally for many years, this could not be performed in Sri Lanka as genetic diagnostic facilities were not available until 2005. Therefore, parents with a thalassaemia major child limited their families to one child, by choice or by termination. The results of this study point to a 21% probability of thalassaemia major in the next child, giving the parents a guarded optimism to conceive another child without thalassaemia disease. With siblings being the highest HLA compatibility for Bone Marrow Transplant, that is now being established in Sri Lanka

  11. Ten years experience in the management of borderline ovarian tumors at Tom Baker Cancer Centre.

    Science.gov (United States)

    Anfinan, Nisrin; Sait, Khalid; Ghatage, Prafull; Nation, Jill; Chu, Pam

    2011-09-01

    The aim of this study was to review the clinical outcomes of patients with borderline ovarian tumors (BOTs) at Tom Baker Cancer Centre (TBCC) and to assess the value of surgical staging. This retrospective study included 138 patients treated for BOTs at TBCC between January 1994 and December 2005. Patients were divided into two groups: group I with complete surgical staging (n = 89) and group II with incomplete surgical staging (n = 49). This population-based study identified patients using the Alberta Cancer Registry. Charts were reviewed by a single person. Data extracted included demographic information and prognostic factors such as age, histological type, laterality of the cyst, presence of microinvasion, and the type of surgical procedure. Data were extracted and entered into a study database for analysis. Overall survival and overall recurrence-free survival of both groups were calculated using the Kaplan-Meier method. Risk factors for recurrence were analyzed using Cox regression analysis. A total of 138 patients were enrolled, with a mean age of 46 years. The median follow-up time was 37 months. The most common histological type of BOT was the serous type found in 70 (50.7%) patients. Microinvasion was identified in four (2.9%) patients. Twelve patients were found to have implants as result of the staging procedure; two of them were invasive implants and both required chemotherapy. Forty-three (31%) patients had conservative surgery and 95 (68.8%) patients had non-conservative surgery. Nine (6.5%) patients experienced recurrence: five (5.6%) patients in group I versus four (8.2%) patients in group II. The presence of microinvasion is the risk factor for recurrence (P = 0.013). The indications for restaging surgery remain controversial, as there was no difference in recurrence rates observed between the study groups. However, surgical staging is important for identifying invasive extraovarian implants that need to be treated with chemotherapy. For patients

  12. Planning ten years ahead a multidisciplinary nuclear research technology institute: the case of IPEN

    International Nuclear Information System (INIS)

    Sousa, Willy Hoppe de

    2011-01-01

    Planning is always a problem in government organizations whose mission involves the development of R and D activities. The current issue of the Institute of Energy and Nuclear Research (IPEN), one of the institutes comprising the National Nuclear Energy Commission (CNEN), is to plan the reconciling the long-term ramifications of a large project whose funding is primarily derived from the budget Union with the R and D agenda of IPEN which is largely driven and funded by science and technology funding agencies. This paper aims at reporting the results of one of the stages of the work developed by IPEN to deal with this problem. In mid-2010, top management of IPEN approved the implementation of a participatory planning effort with the following guidelines: (1) focus on two of the three finalist functions of IPEN - Research and Development (R and D) and Products and Services (P and S), (2) results orientation with a time horizon of 10 years, (3) incorporation of the unfolding of a large project in this planning effort (this project has its own planning) and (4) the source of information of the planning process would be the teams involved in the research lines and projects (LPP's) and the lines of production activities (LAP's) - the lowest grouping level in the current planning framework of IPEN. The planning process developed was based on an adaptation of a technique known as technology roadmapping. The data were collected through a web questionnaire. At the end of the data collection in mid- December 2010 89 LPP's and LAP 28's responses were recorded. For the purposes of this article the following groups of information related to R and D finalist function are presented: Where are we now?: (1) Profile of the current team; (2) Motivation of research and (3) Sources used for identification R and D goals. How can we get there?: (4) Profile of research partners, and (5) Profile of the necessary changes. Where do we want to go?: (6) Classification of results by areas and (7

  13. Ten-year experience of more than 35,000 orofacial clefts in Africa.

    Science.gov (United States)

    Conway, Julia C; Taub, Peter J; Kling, Rochelle; Oberoi, Kurun; Doucette, John; Jabs, Ethylin Wang

    2015-02-14

    Surgical correction of orofacial clefts greatly mitigates negative outcomes. However, access to reconstructive surgery is limited in developing countries. The present study reviews epidemiological data from a single charitable organization, Smile Train, with a database of surgical cases from 33 African countries from 2001-2011. Demographic and clinical patient data were collected from questionnaires completed by the participating surgeons. These data were recorded in Excel, analyzed using SPSS and compared with previously reported data. Questionnaires were completed for 36,384 patients by 389 African surgeons. The distribution of clefts was: 34.44% clefts of the lip (CL), 58.87% clefts of the lip and palate (CLP), and 6.69% clefts of the palate only (CP). The male to female ratio was 1.46:1, and the unilateral: bilateral ratio 2.93:1, with left-sided predominance 1.69:1. Associated anomalies were found in 4.18% of patients. The most frequent surgeries included primary lip/nose repairs, unilateral (68.36%) and bilateral (11.84%). There was seasonal variation in the frequency of oral cleft births with the highest in January and lowest by December. The average age at surgery was 9.34 years and increased in countries with lower gross domestic products. The average hospital stay was 4.5 days. The reported complication rate was 1.92%. With the exception of cleft palates, results follow trends of worldwide epidemiologic reports of 25% CL, 50% CLP, and 25% CP, 2:1 unilateral:bilateral and left:right ratios, and male predominance. Fewer than expected patients, especially females, presented with isolated cleft palates, suggesting that limitations in economic resources and cultural aesthetics of the obvious lip deformity may outweigh functional concerns and access to treatment for females. A fewer than expected associated anomalies suggests either true ethnic variation, or that more severely-affected patients are not presenting for treatment. The epidemiology of orofacial

  14. Ten-year monitoring of high-rise building columns using long-gauge fiber optic sensors

    International Nuclear Information System (INIS)

    Glisic, B; Inaudi, D; Lau, J M; Fong, C C

    2013-01-01

    A large-scale lifetime building monitoring program was implemented in Singapore in 2001. The monitoring aims of this unique program were to increase safety, verify performance, control quality, increase knowledge, optimize maintenance costs, and evaluate the condition of the structures after a hazardous event. The first instrumented building, which has now been monitored for more than ten years, is presented in this paper. The long-gauge fiber optic strain sensors were embedded in fresh concrete of ground-level columns, thus the monitoring started at the birth of both the construction material and the structure. Measurement sessions were performed during construction, upon completion of each new story and the roof, and after the construction, i.e., in-service. Based on results it was possible to follow and evaluate long-term behavior of the building through every stage of its life. The results of monitoring were analyzed at a local (column) and global (building) level. Over-dimensioning of one column was identified. Differential settlement of foundations was detected, localized, and its magnitude estimated. Post-tremor analysis was performed. Real long-term behavior of concrete columns was assessed. Finally, the long-term performance of the monitoring system was evaluated. The researched monitoring method, monitoring system, rich results gathered over approximately ten years, data analysis algorithms, and the conclusions on the structural behavior and health condition of the building based on monitoring are presented in this paper. (paper)

  15. Prevalence of oropharyngeal beta-lactamase-producing Capnocytophaga spp. in pediatric oncology patients over a ten-year period

    Directory of Open Access Journals (Sweden)

    Cormier Michel

    2005-05-01

    Full Text Available Abstract Background The aim of this study was to evaluate the prevalence of beta-lactamase-producing Capnocytophaga isolates in young children hospitalized in the Pediatric Oncology Department of Hôpital Sud (Rennes, France over a ten-year period (1993–2002. Methods In neutropenic children, a periodic survey of the oral cavity allows a predictive evaluation of the risk of systemic infections by Capnocytophaga spp. In 449 children with cancer, 3,053 samples were collected by oral swabbing and plated on TBBP agar. The susceptibility of Capnocytophaga isolates to five beta-lactams was determined. Results A total of 440 strains of Capnocytophaga spp. were isolated, 309 (70% of which were beta-lactamase producers. The beta-lactamase-producing strains were all resistant to cefazolin, 86% to amoxicillin, and 63% to ceftazidime. The proportion of strains resistant to third-generation cephalosporins remained high throughout the ten-year study, while susceptibility to imipenem and amoxicillin combined with clavulanic acid was always conserved. Conclusion These results highlight the risk of antibiotic failure in Capnocytophaga infections and the importance of monitoring immunosuppressed patients and testing for antibiotic susceptibility and beta-lactamase production.

  16. The occurrence of osteoarthritis at a minimum of ten years after reconstruction of the anterior cruciate ligament

    Directory of Open Access Journals (Sweden)

    Patt Thomas W

    2008-06-01

    Full Text Available Abstract Objective The objective of this study was to evaluate the incidence of radiographic osteoarthritis in the operated knee in comparison with the contralateral knee ten years after a bone-tendon bone patellar autograft ACL-reconstruction and to evaluate to which level patients regain activity ten years after reconstruction. Methods Fifty-three patients with ACL instability were operated arthroscopically using the central third of the patellar tendon as a bone-tendon-bone autograft. At a minimum of 10 year follow up 28/44 patients matched the inclusion criteria and could be reached for follow-up. Evaluation included a patient satisfaction evaluation using a Visual Analog Scale, physical examination (International Knee Documentation Committee score, Tegner score, Lysholm score, KT-1000 stabilometry and a radiological evaluation (Kellgren and Fairbanks classification. Results The patients' satisfaction, at a mean of 10,3 year follow-up, measured with a VAS score (0–10 was high with a mean of 8.5 (range 4 to 10. The KT 1000 arthrometer laxity measurements revealed in 55% of the patients an A rating (1–2 mm, in 29% a B rating (3–5 mm and in 16% a C rating (6–10 mm. According to the Tegner score 54% of the patients were able to perform at the same activity level as pre-operatively. The mean pre-operative Tegner score was 6.8 and the mean post-operative Tegner score was 6.0 at final follow up. The Lysholm score showed satisfactory results with a mean of 91 points (range 56 to 100. According to the Kellgren and Fairbank classifications, there is a significant difference (p Conclusion The patellar BTB ACL reconstruction does not prevent the occurrence of radiological OA after 10 years but does help the patient to regain the pre-operative level of activity.

  17. Repair of an Autologous Saphenous Vein Graft Aneurysm Ten Years after Renal Artery Reconstruction during Live Donor Renal Transplantation.

    Science.gov (United States)

    Oelschlaeger, Markus; Sokolakis, Ioannis; Kalogirou, Charis; Frey, Lea; Riedmiller, Hubertus; Kübler, Hubert; Kellersmann, Richard; Vergho, Daniel

    2017-10-06

    Saphenous vein graft (SVG) aneurysms (SVGA) after renal transplantation represents a rare vascular complication with subsequent challenging multidisciplinary treatment. We present a case of a 30-year-old female who received a live donor kidney transplantation for end-stage renal disease that was caused due to the hemolytic uremic syndrome. Postoperatively, an insufficient graft perfusion due to an arterial kinking was noted and repaired using an autologous SVG interposition. Ten years later, a 3-cm aneurysm of the SVG at the anastomotic site with the common iliac artery was discovered. Multidisciplinary surgical exploration with excision of the aneurysm-carrying vein graft and interposition of a new autologous SVG was successfully carried out with preservation of renal allograft's function. Treatment of SVGA after rental transplantation with a new autologous SVG is challenging but feasible, requiring a multidisciplinary approach in order to guarantee successful rates and to prevent allograft loss. © 2017 S. Karger AG, Basel.

  18. Mucinous carcinoid of the ovary: report of a case with metastasis in the contralateral ovary after ten years

    Directory of Open Access Journals (Sweden)

    Patricia C. Ewing

    2010-09-01

    Full Text Available Monodermal teratomas of the ovary can take the form of carcinoid tumors of which there are several types, mucinous carcinoid being the least common. Very few cases of primary mucinous carcinoid of the ovary have been reported in the literature and the behavior of these tumors over the long term is unclear. We describe a case of primary mucinous carcinoid of the ovary in a 39-year-old woman treated with unilateral salpingo-oophorectomy, where a metastasis occurred in the contralateral ovary ten years later. This case demonstrates that mucinous carcinoid of the ovary can metastasize even after a long interval, and careful follow-up of patients, particularly those treated conservatively, is appropriate.

  19. Low grade papillary transitional cell carcinoma pelvic recurrence masquerading as high grade invasive carcinoma, ten years after radical cystectomy

    Directory of Open Access Journals (Sweden)

    Mortazavi Amir

    2008-09-01

    Full Text Available Abstract Background Tumor recurrence following radical cystectomy for a low-grade superficial transitional cell carcinoma (TCC is exceedingly uncommon and has not been reported previously. Case presentation We describe a case of a young male presenting with anorexia, weight loss and a large, painful locally destructive pelvic recurrence, ten years after radical cystoprostatectomy. The pathology was consistent with a low-grade urothelial carcinoma. After an unsuccessful treatment with cisplatin-based chemotherapy, the patient underwent a curative intent hemipelvectomy with complete excision of tumor and is disease free at one year follow-up. Conclusion A literature review related to this unusual presentation is reported and a surgical solutions over chemotherapy and radiotherapy is proposed.

  20. Ipsilateral combination of Galeazzi and Monteggia fractures in a ten-year-old patient: a case report.

    Science.gov (United States)

    Akalin, Yavuz; Akinci, Orhan; Kayali, Cemil

    2010-01-01

    Galeazzi fractures represent approximately 3 to 6 percent of forearm fractures, whereas Monteggia fractures represent 1 to 2 percent. The combination of these injuries in the same extremity is an exceedingly rare occurrence. We report a case of ipsilateral combination of Galeazzi and Monteggia fractures in a ten-year-old patient. The patient was treated with closed reduction and internal fixation with Kirschner pins. The distal radioulnar and radiocapitellar joint relationships were restored and the fractures healed. The patient proceeded to obtain a satisfactory functional result three years later. Internal fixation is a safe method for such complex forearm fractures in older children and allows post-operative rehabilitation with the advantage of early mobilization.

  1. Socioeconomic position and ten-year survival and virologic outcomes in a Ugandan HIV cohort receiving antiretroviral therapy.

    Directory of Open Access Journals (Sweden)

    Andrew G Flynn

    Full Text Available Lifelong ART is essential to reducing HIV mortality and ending the epidemic, however the interplay between socioeconomic position and long-term outcomes of HIV-infected persons receiving antiretroviral therapy (ART in sub-Saharan Africa is unknown. Furthering the understanding of factors related to long-term ART outcomes in this important region will aid the successful scale-up of ART programs. We enrolled 559 HIV-infected Ugandan adults starting ART in 2004-2005 at the Infectious Diseases Institute in Kampala, Uganda and followed them for 10 years. We documented baseline employment status, regular household income, education level, housing description, physical ability, and CD4 count. Viral load was measured every six months. Proportional hazard regression tested for associations between baseline characteristics and 1 mortality, 2 virologic failure, and 3 mortality or virologic failure as a composite outcome. Over ten years 23% (n = 127 of participants died, 6% (n = 31 were lost-to-follow-up and 23% (107/472 experienced virologic treatment failure. In Kaplan-Meier analysis we observed an association between employment and mortality, with the highest cumulative probability of death occurring in unemployed individuals. In univariate analysis unemployment and disease severity were associated with mortality, but in multivariable analysis the only association with mortality was disease severity. We observed an association between higher household income and an increased incidence of both virologic failure and the combined outcome, and an association between self-employment and lower incidence of virologic failure and the combined outcome when compared to unemployment. Formal education level and housing status were unrelated to outcomes. It is feasible to achieve good ten-year survival, retention-in-care, and viral suppression in a socioeconomically diverse population in a resource-limited setting. Unemployment appears to be related to adverse 10

  2. Ten years of EUR

    International Nuclear Information System (INIS)

    Chatry, J.-P.; Berbey, P.

    2002-01-01

    As the nuclear option becomes more and more credible all over the word, the major European electricity producers want to be able to build new nuclear power plants as soon as the economic interest or the necessity reappear. To account for the changes in the conditions for construction (market organisation, licensing requirements, design objectives, etc.) compared to the ones existing up to the beginning of the 90s, the utilities and the vendors have set up various action plans to support the development of future nuclear plant designs. These new designs shall be acceptable by the regulatory bodies, attractive to the public and profitable for the electricity producer. Producing a common European Utility Requirement (EUR) document that sets out the requested targets is one of the basic tasks for this renewal

  3. Ten years after Chernobyl

    International Nuclear Information System (INIS)

    Becker, K.

    1996-01-01

    As was amply demonstrated during the EU/IAEA/WHO Summing-up-Conference in Vienna, Austria, April 8-12, 1996, the radiological consequences of the Chernobyl accident were, fortunately, not as serious as frequently presented in the media: 28 people died from acute radiation syndrome in 1986, 14 more of possibly radiation-related causes since. Of the <1000 thyroid cancers in children, 90 to 95% are curable. There have so far been no other demonstrable increases in the former Soviet Union, as well as in Western Europe, of leukemias, solid cancers, or genetic defects, nor are any to be expected in the future. Even among the open-quotes liquidatorsclose quotes with doses ∼100 mSv, of the ∼150 additional expected leukemias during the 10 yr after the accident, none have been observed. The economical, social, and political consequences, however, both in the former Soviet Union and in Western Europe, have been very substantial. Whole countries developed an hysterical 'radiation sickness.' As A. Merkel, the German Minister of Environment and Reactor Safety, who chaired the conference, pointed out, 'the radiation sensitivity of societies far exceeds that of individuals.' It is obvious that important groups in Ukraine, Belaurus, and Russia try to blame a large fraction of all economic, social, and health problems during the last decade, which are substantial (∼ 6 yr less life expectancy, twice the homicides and traffic deaths, increased alcoholism, and so forth), on radiation of the Chernobyl accident in an effort to attract more support. Western scientists refute such claims but admit large non-radiation-related problems caused by the accident

  4. AFGHANISTAN TEN YEARS AFTER...

    Directory of Open Access Journals (Sweden)

    Slavomír Horák

    2011-12-01

    Full Text Available The article focuses on the analysis of the internal politics of Afghanistan after 2001 and evaluates the results of state- and nation-building. The emphasis on internal politics is the only possible way to understand the processes in the country and work out the strategy for the country after the planned withdrawal (or limitation of foreign troops from the country. In this context, the fragmentation and deepening cleavages among various social strata in the country (ethnic, sub-ethnic is considered to be a crucial determinant of the development in the country. Several power groups define diverse attitudes towards the character of the future Afghan state. These circumstances could lead to the new round of the military conflict after the removal of foreign troops which are considered as a negative factor by a large part of the Afghan elite, albeit they serve as one of the stabilization factors in the country. However, the international community has (and will have limited tools and influence to prevent any prospective conflict in the country.

  5. Ten-Year Results of Home Vision-Screening Test in Children Aged 3-6 Years in Seoul, Korea.

    Science.gov (United States)

    Jeong, Seong Hun; Kim, Ungsoo Samuel

    2015-01-01

    To characterize the prevalence of refractive error and amblyopia among three- to six-year-old children during the period from 2002 to 2011. About 31,400 children annually (from 16,592 to 40,816) during the period from 2002 to 2011 were enrolled. The preschool vision screening was performed by the Korean Foundation for the Prevention of Blindness (KFPB) annually during a period that extended from March to September. We reviewed the KFPB annual report about the home vision-screening test as performed during the period from 2002 to 2011. Changes in the prevalence and types of refractive error, strabismus, and amblyopia that manifested throughout this period were analyzed. The prevalence of refractive errors ranged from 1.10% in 2002 to 0.42% in 2011. The prevalence of hyperopia and myopia changed little throughout the 10-year study period. Myopia and hyperopia were equally common among the population examined (χ(2)-test, p = 0.137). The prevalence of anisometropia decreased over time. The annual prevalence of amblyopia ranged from 0.39% to 0.06%, while the overall prevalence of amblyopia dropped from 0.25% in 2002 to 0.06% in 2011. The prevalence of strabismus was highest in 2006 (0.30%) and had decreased by 0.06% in 2011. The type of strabismus showed no significant difference over time (χ(2)-test, p = 0.579). The prevalence of amblyopia, refractive error, anisometropia, and strabismus was lower in 2011 than in early 2000. The prevalence of hyperopia and myopia as well as strabismus remained similar throughout the study period.

  6. Surgical treatment of thoraco-abdominal and low thoracic aneurysms of the aorta. One single center experience over ten years.

    Science.gov (United States)

    El Arid, J M; Creemers, E; Limet, R

    2006-01-01

    This work presents the results of surgery in thoraco-abdominal aortic aneurysms (TAA) and thoracic descending aortic aneurysms (TDA) in one single center between January 1rst, 1996 and December 31, 2005. It concerns open surgery in 42 and endovascular procedures in ten patients. Forty two patients (11 TDA and 31 TAA (4 type I, 12 type II , 6 type III and 9 type IV)) define the open surgery series. Twenty six patients were operated on elective basis and 16 patients in emergency condition. Surgical correction was made under partial cardio-pulmonary bypass (PCPB) in 70% of cases via femoral vessels; most significant intercostal arteries were reimplanted and cerebro-spinal fluid (CSF) drainage used in half of the cases. Operative mortality was zero in the elective group (0/26) and attained 19% in the emergent group (3/16). Mortality was linked to cerebrovascular accidents (CVA) in two cases and post-pump left lung hemorrhagic infarction in one case. The paraplegia accounts 2/26 in the elective group and one in the emergent group (1/16). That is 7.1% in both groups. At the end of five years, survival is 66% in elective group and 74% in the emergency group. Ten patients (5 TDA and 5 TAA (2 type I, 3 type III)) were treated endovascularly. Operative mortality and postoperative paraplegia were nil.

  7. Urban energy management today: Ten year compendium of UCETF programs. Products and expertise of the Urban Consortium Energy Task Force, 1979--1989

    Energy Technology Data Exchange (ETDEWEB)

    1990-01-01

    The reports listed in this Overview summarize projects conducted through the Urban Consortium Energy Task Force by local government staff who have defined and implemented many of the energy strategies described above. Reports from their projects illustrate effective approaches to plan and implement these strategies, as well as software tools, surveys, and technical instruments valuable to other local government officials conducting similar projects.

  8. A ten year (1999-2008) retrospective study of amoebiasis in University Malaya Medical Centre (UMMC), Kuala Lumpur, Malaysia.

    Science.gov (United States)

    Farhana, F; Jamaiah, I; Rohela, M; Abdul-Aziz, N M; Nissapatorn, V

    2009-12-01

    This is a ten year (1999-2008) retrospective study of amebiasis in patients admitted to UMMC. A total of 34 cases were analyzed. The most common were amebic liver abscess 22(65%) and the rest were amoebic dysentery 12(35%). Majority of the cases occurred among Malaysians 29(85%), with Chinese 14(41%), followed by the Malays 9(26%) and the Indians 6(18%). Foreigners made up of one Indonesian, one Pakistani and three Myanmarese and constituted 5(15%) of the total cases. Males 24(71%) were more commonly affected. Most of the cases occurred between the age group of 40-49 years, 8(23%) and 60 years and above, 8(23%). Age group of 20-50 years constituted 20(60%) of the cases. The most common clinical presentations were fever with chills and rigors 26(76%), diarrhoea 20 (59%), right hypochondrium pain 17(50%), abdominal pain 17(50%), hepatomegaly 16 (47%) and jaundice 7(20%). All were discharged well after treatment except for one case of death in a 69-year-old Chinese male with amebic liver abscess.

  9. Retrospective Study of Tapered One-Piece Implants Placed Over a Ten-Year Period in a Single Private Practice.

    Science.gov (United States)

    Minichetti, John C; D'Amore, Joseph C; Hong, Anna Y-J

    2018-04-01

    Today, clinicians have a variety of treatment modalities available to address the increasing number of implant procedures performed each year. Single-stage implant surgery is now commonly used in implant dentistry. With patients' demands for immediate restoration, the utilization of 1-piece implants is gaining acceptance. This article reports the results of tapered 1-piece implants (Zimmer Biomet) placed in a single practice over a 10-year period. A total of 33 1-piece dental implants were placed in 24 patients and provisionally restored out of occlusion at the time of surgery. All 33 implants were definitively restored with ceramometal crowns after 3 months of provisionalization. Implant survival and success rates were 100% after 2.6-10 years of follow-up. Only 1 minor complication of crestal bone remodeling occurred among the 33 implants placed. Adequately stabilized tapered 1-piece implants can be successfully restored out of occlusion at the time of implant placement and definitively loaded in occlusion 3 months without adversely affecting function or esthetics. Additional long-term controlled studies are recommended to further understand these findings.

  10. Ten Years Evidence-Based High-Tech Acupuncture—A Short Review of Peripherally Measured Effects

    Directory of Open Access Journals (Sweden)

    Gerhard Litscher

    2009-01-01

    Full Text Available Since 1997, the Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine of Graz Medical University has been dealing with the demystification of acupuncture and examining, using non-invasive methods, how different stimulation modalities (manual needle acupuncture, laserneedle acupuncture and electro acupuncture affect peripheral and central functions. Laser is also an important instrument for acupuncture. One only needs to mention the treatment of children or of patients with needle phobia. The laserneedle acupuncture, which was examined scientifically for the first time in Graz, represents a new painless acupuncture method for which up to ten laserneedles are glued to the skin, but not stuck into it. This first part of the short review article summarizes some of the peripherally measured effects of acupuncture obtained at the Medical University of Graz within the last 10 years.

  11. Ten years of experience in extraction chromatographic processes for the recovery, separation and purification of actinides elements

    International Nuclear Information System (INIS)

    Madic, C.; Bourges, J.; Koehly, G.

    1984-06-01

    Ten years ago the extraction chromatographic technique was developed for preparative purposes and is now applied for all chemicals separations needed for the production of actinides isotopes. That technique appears to be simple and flexible. It can be used for the production of microgram to kilogram amounts of actinide isotopes. This paper focuses on the experience gained and describes some peculiar production of actinide isotopes solved by using extraction chromatographic technique. After a review of extracting molecules and equipment, treatment of irradiated targets (preparation of Pu 238 and removal of neptunium, production of Am 243 and Cm 244), recovery of actinides from alpha aqueous wastes (preparation of Am 241) and recovery of decay products from aged actinide stocks (recovery of Am 241 from Pu stocks, of U 234 from Pu 238 stocks) are described

  12. Ten years after the IOM report: Engaging residents in quality and patient safety by creating a House Staff Quality Council.

    Science.gov (United States)

    Fleischut, Peter M; Evans, Adam S; Nugent, William C; Faggiani, Susan L; Lazar, Eliot J; Liebowitz, Richard S; Forese, Laura L; Kerr, Gregory E

    2011-01-01

    Ten years after the 1999 Institute of Medicine report, it is clear that despite significant progress, much remains to be done to improve quality and patient safety (QPS). Recognizing the critical role of postgraduate trainees, an innovative approach was developed at New York-Presbyterian Hospital, Weill Cornell Medical Center to engage residents in QPS by creating a Housestaff Quality Council (HQC). HQC leaders and representatives from each clinical department communicate and partner regularly with hospital administration and other key departments to address interdisciplinary quality improvement (QI). In support of the mission to improve patient care and safety, QI initiatives included attaining greater than 90% compliance with medication reconciliation and reduction in the use of paper laboratory orders by more than 70%. A patient safety awareness campaign is expected to evolve into a transparent environment where house staff can openly discuss patient safety issues to improve the quality of care.

  13. The statistical analysis of failure of a MEVATRON77 DX67 linear accelerator over a ten year period

    CERN Document Server

    Aoyama, H; Tahara, S; Uno, H; Kadohisa, S; Azuma, Y; Nakagiri, Y; Hiraki, Y

    2003-01-01

    A linear accelerator (linac) takes a leading role in radiation therapy. A linac consists of complicated main parts and systems and it is required that highly accurate operational procedures should be maintained. Operational failure occurs for various reasons. In this report, the failure occurrences of one linac over a ten year period were recorded and analyzed. The subject model was a MEVATRON77 DX67 (Siemens, Inc). The failure rate for each system, the form classification of the contents of failure, the operation situation at the time of failure, and the average performance life of the main parts were totaled. Moreover, the relation between the number of therapies that patients received (operating efficiency) and the failure rate within that number and the relation between environment (temperature and humidity) and the failure rate attributed to other systems were analyzed. In this report, irradiation interruption was also included with situations where treatment was unable to begin in total for the number o...

  14. Similarities and differences between smoking and non-smoking ten-year-old children in primary schools.

    Science.gov (United States)

    Hrubá, Drahoslava; Zaloudíková, Iva; Matĕjová, Halina

    2010-03-01

    For the majority of smokers, smoking is related to other forms of risk behaviour, especially poorer eating habits. The primary preventive educational programme "No smoking is a norm" focuses on children of younger school age (under 10 yrs), enables comparison and statistical evaluation of whether there are any differences (and which) between ten-year-olds with various smoking experiences, with special attention paid to their exposure to the influence of smokers, and their eating habits. Analysis of data gained from a questionnaire compared groups of boys and girls, smokers and non-smokers, and children from families with no smokers, occasional smokers, and frequent smokers. Statistical significance of the differences was tested in the EPI INFO programme by means of the chi2 test. From 1,082 children, almost one quarter (22.9%) have already tried smoking, boys more frequently (25%) than girls (19%) (p friends, and some (4%) even bought them. Children with smoking experience more often come from smokers' families and more often have smoking siblings and friends who offer them cigarettes. Children claimed to have consumed alcoholic drinks over the past month, repeatedly smoking more often than those with one attempt (aprox. 81% vs 58%) and never smokers (32%). Smokers also more frequently ate salty snacks such as crisps, sausages, and fast foods. The circumstance of whether there are smokers in the child's household or not significantly influenced children's opinions on the smoking of men/boys and women/girls (fewer critics and more admirers in smokers' families), selection of friends, availability of cigarettes, and smoking behaviour of the children. The examination of a cohort of ten-year-olds in a semi-longitudinal study confirmed the growing trend of experimenting with smoking. Strong relations to smoking behaviour in families were identified--such that influence a more tolerant approach to parents' smoking, selection of smoking or non-smoking friends, more

  15. Compartmentalization today

    Science.gov (United States)

    Kevin T. Smith

    2006-01-01

    For more than 30 years, the compartmentdization concept has helped tree care practitioners and land managers interpret patterns of decay in living trees. Understanding these patterns can help guide the selection of treatments that meet the needs of people and communities while respecting the underlying tree biology. At its simplest, compartmentalization resists the...

  16. [Incest today].

    Science.gov (United States)

    Gabel, Marceline

    2002-01-01

    The issue explored is incest against children. This paper summarizes the changes on knowledge on this topic since the years 1850 to nowadays. The main focus is placed on the specificity of incest and sexual aggression towards minors as criminal behaviours. Finally, the lake of research, which leaves many questions unanswered, is underlined.

  17. PLOS Neglected Tropical Diseases: Ten years of progress in neglected tropical disease control and elimination … More or less.

    Directory of Open Access Journals (Sweden)

    Peter Hotez

    2017-04-01

    Full Text Available This year PLOS Neglected Tropical Diseases (PLOS NTDs celebrates its tenth anniversary following the publication of the first issue in 2007 [1]. When PLOS NTDs was founded, the framework of the neglected tropical diseases (NTDs as an alternative to "other diseases" (as they were then referred to in the Millennium Development Goals was just getting started-especially for Africa [2, 3]. In the decade since, PLOS NTDs has overseen enormous successes in NTD control and elimination. Here, we want to briefly review the ten year progress made towards the control or elimination of the diseases now identified by the WHO as NTDs. Many of the details are highlighted in PLOS NTDs papers cited here, but the summary information is based on the recently released Global Burden of Disease (GBD Study 2015 (also launched with Gates Foundation support that summarized past-decade changes in disease prevalence, mortality, or disability rates (from the years 2005 to 2015 [4-6], as well as the GBD Study 2013 that summarizes disease prevalence changes over a longer time horizon from 1990 to 2013 [7].

  18. A prospective study with ten years follow-up of two-hundred patients with proximal femoral fracture.

    Science.gov (United States)

    Galler, M; Zellner, M; Roll, C; Bäuml, C; Füchtmeier, B; Müller, F

    2018-04-01

    The proximal femoral fracture is one of the most common injuries in the elderly. Nevertheless, no results beyond the second year post surgery have been reported in the literature. Therefore, the purpose of this study was to evaluate any revision and mortality within 10 years follow-up as well as the walking ability of still alive patients. A total of 200 consecutive patients were included. A prospective database was first used to collect the demographic data. Exactly ten years after the surgery, a final evaluation was conducted by telephone for every patient. Any revision, any contralateral as well as other fractures and the date of death were recorded. For all patients who were still alive, the mobility score according to Parker was also surveyed. The average age was 79.0 years (SD: 12.5); women were affected at higher numbers (73.5%). The total surgical revision rate was 17.5% (35/200), due in particular to hematoma (9×) or infection (7×). A surgical revision later than two years was only needed in three patients (1.5%). The risk of another fracture caused by a fall was 19% (38/200), most often a contralateral femoral fracture (22/200; 11%) that happened on average 51.9 months (1-97) after the initial surgery. The risk of a contralateral femoral fracture was 15.4% (22/143) in patients who survived the first year post surgery. The postoperative mortality was 1, 2, 5 and 10 years or 23.5%, 32.5%, 55% as well as 81.5%, respectively. An average Parker's mobility score of 6.3 points (0-9) was determined for the 37 patients (18.5%) who were still alive at the time of the follow-up. The long-term study showed that revision surgery was only required in 3/200 patients (1.5%) beyond the second year of that surgery. On the other hand, more than half of all patients had already passed away five years after the initial surgery. The exact incidence of a contralateral femoral fracture was 11.9%, climbing to 15.4% if the patient survived at least one year. Nearly every fifth

  19. Land evaluation suitability for settlement based on soil permeability, topography and geology ten years after tsunami in Banda Aceh, Indonesia

    Directory of Open Access Journals (Sweden)

    Muhammad Rusdi

    2015-12-01

    Full Text Available Years after the tragedy of the tsunami in Banda Aceh researchers are still saddled with the problem of water permeability, slope and geology suitability for settlements. Social and ecological vulnerability to disasters and outcomes of Oceanic earthquakes causing tsunamis remain an indelible phobia to potential residents at the western coast of Sumatra upto the northern part of Indonesia. Ten years after the disaster, this study evaluates the topography of the area to determine the level of suitability of the area for human habitat. This article examines the concept of land suitability evaluation and its potential as a tool of determining appropriateness of a settlement. The focus of the study centered on the application of geographic information systems GIS in handling spatial data permeability, slope and geology of the land in accordance with the FAO land suitability standard. To ensure that the application works, it requires geospatial analysis compiled based on the permeability, slope and geology that can be observed and measured for the residential requirements. Results showed that almost all the cities within Banda Aceh are suitable for residency (Ordos.

  20. Influence of marital status on testosterone levels-A ten year follow-up of 1113 men

    DEFF Research Database (Denmark)

    Holmboe, Stine A; Priskorn, Lærke; Jørgensen, Niels

    2017-01-01

    Based on a large population of 1113 men aged 30-60 at baseline (mean: 44.1 years, standard deviation: 10.5), we investigated whether intra-individual changes in testosterone (T) and related reproductive hormones during a ten year period were dependent of marital status at baseline and follow...... in testosterone was observed. However, independent of age and lifestyle, we observed that men who went from unmarried to married (n=81) during the study period experienced an accelerated age-related decline in testosterone (-6.6nmol/L) whereas men who went from married to unmarried (n=67) experienced...... an attenuated age-related decline (-2.3nmol/L). Men who were either married or unmarried at both time points (n=167, n=798, respectively) had a testosterone decline in between (-3.7nmol/L and -4.6nmol/L, respectively). Changes in T/LH ratio did not differ according to marital status indicating that the lowered...

  1. AN ANALYSIS OF TEN YEARS OF THE FOUR GRAND SLAM MEN'S SINGLES DATA FOR LACK OF INDEPENDENCE OF SET OUTCOMES

    Directory of Open Access Journals (Sweden)

    Denny Meyer

    2006-12-01

    Full Text Available The objective of this paper is to use data from the highest level in men's tennis to assess whether there is any evidence to reject the hypothesis that the two players in a match have a constant probability of winning each set in the match. The data consists of all 4883 matches of grand slam men's singles over a 10 year period from 1995 to 2004. Each match is categorised by its sequence of win (W or loss (L (in set 1, set 2, set 3,... to the eventual winner. Thus, there are several categories of matches from WWW to LLWWW. The methodology involves fitting several probabilistic models to the frequencies of the above ten categories. One four-set category is observed to occur significantly more often than the other two. Correspondingly, a couple of the five-set categories occur more frequently than the others. This pattern is consistent when the data is split into two five-year subsets. The data provides significant statistical evidence that the probability of winning a set within a match varies from set to set. The data supports the conclusion that, at the highest level of men's singles tennis, the better player (not necessarily the winner lifts his play in certain situations at least some of the time

  2. Mexico: Yesterday and Today.

    Science.gov (United States)

    Koscielny, Mary Patrice

    This guide features Mexican history, culture, and the environment in the years past and present. This guide discusses five periods of Mexican history, including: (1) Indian Period; (2) Colonial Period; (3) Independence Movement; (4) The Revolution; and (5) Mexico Today. Each section has goals for the students, background readings, and activities…

  3. Decreased Opioid Utilization and Cost at One Year in Chronic Low Back Pain Patients Treated with Transcutaneous Electric Nerve Stimulation (TENS).

    Science.gov (United States)

    Pivec, Robert; Minshall, Michael E; Mistry, Jaydev B; Chughtai, Morad; Elmallah, Randa K; Mont, Michael A

    2015-11-01

    Chronic low back pain (CLBP) may be treated without opioids through the use of transcutaneous electrical nerve stimulation (TENS). However, no study has evaluated its clinical effect and economic impact as measured by opioid utilization and costs. The purpose of this study was to evaluate patients who were given TENS for CLBP compared to a matched group without TENS at one-year follow-up, to determine differences between opioid consumption. Opioid utilization and costs in patients who did and did not receive TENS were extracted from a Medicare supplemental administrative claims database. Patients were selected if they had at least two ICD-9-CM coded claims for low back pain in a three-month period and were then propensity score matched at a 1:1 ratio between patients who received TENS and those who did not. There were 22,913 patients in each group who had a minimum follow-up of one year. There were no significant demographic or comorbidity differences with the exception that TENS patients had more episodes of back pain. Significantly fewer patients in the TENS group required opioids at final follow-up (57.7 vs. 60.3%). TENS patients also had significantly fewer annual per-patient opioid costs compared to non-TENS patients ($169 vs. $192). There were significantly lower event rates in TENS patients compared to non-TENS patients when measured by opioid utilization (characterized by frequency of prescription refills) (3.82 vs. 4.08, respectively) or pharmacy utilization (31.67 vs. 32.25). The TENS group also demonstrated a significantly lower cost of these utilization events ($44 vs. $49) and avoided more opioid events (20.4 events fewer per 100 patients annually). Treatment of CLBP with TENS demonstrated significantly fewer patients requiring opioids, fewer events where a patient required an opioid prescription, and lower per-patient costs. Since TENS is both non-invasive and a non-narcotic, it may potentially allow physicians to be more aggressive in treating CLBP

  4. Clinical presentation and treatment outcome of molar pregnancy: Ten years experience at a Tertiary Care Hospital in Dammam, Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Ayman A Al-Talib

    2016-01-01

    Full Text Available Objectives: To study the clinical presentation and treatment outcome of molar pregnancy at a Tertiary Care Hospital in Dammam, Saudi Arabia. Materials and Methods: Reviewed medical records of all molar pregnancy cases among all the deliveries at a tertiary care hospital in Dammam from 2005 to 2014, after approval by institutional ethical review committee. Data abstracted included patient′s age, parity, presenting symptoms, gestational age at diagnosis, uterine size, ultrasonographic findings, BhCG level at the time of diagnosis and at follow-up after evacuation, and blood loss during evacuation. Data was entered and analyzed using Excel; frequency distribution for categorical variables and descriptive statistics for continuous variables were computed. Results: Of a total of 25,000 deliveries in ten years, 22 cases of complete molar pregnancy were encountered: 0.9 cases of molar pregnancy per 1000 pregnancies. Majority of patients (63.7% were older than 35 years, and were nulliparous (45.5%. The commonest symptom was vaginal bleeding (86.4% followed by hyperemesis gravidarum (41.0%; Hyperthyroidism was seen in 1 patient (4.5%. Ovarian enlargement by theca-lutin cyst was seen in 3 patients (13.6%. The majority of patients (63.6% had normal BhCG within 9 weeks (63 days after suction curettage. The majority of the cases followed a benign course. Conclusion: Aged older than 35 years seems a risk factor and vaginal bleeding is the commonest presenting symptom. Early booking of pregnant women to antenatal care clinics and routine first trimester ultrasound made diagnosis easier and earlier before complications appear.

  5. The President of the Republic in the constitutional order of Serbia: Ten years of the Constitution of 2006

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    Đorđević Aleksandar S.

    2016-01-01

    Full Text Available It is undoubted that the President of the Republic of Serbia represents the most controversial issue debating in constitutional theory and practice. We can find completely opposite attitudes toward the constitutional status of the President of the Republic: on one hand, the prevailing opinion that the President of the Republic has an active role in the executive branch of the government, but on the other hand, the opinion that the President of the Republic is a figurehead and has only a moderating role. If we remain focused only on normative analysis, there is no doubt that we will be brought to a conclusion that the constitution-maker insisted on the moderating role of the President of the Republic making him an independent constitutional body providing the balance in the system of government. In the constitutional practice, in the previous ten years, we have been in a position to see two totally different 'stiles of presidency'. None of them is in accordance with the 'constitutional picture' of the institution. From 2007 to 2012 president Tadić was a central constitutional figure. He tended to concentrate all constitutional powers in his hands using the position of the leader of the strongest political party. With coming into power president Nikolic, who gave up the function of the president of the party, constitutional and political power moved almost completely to the president of the Government. The president of the Republic acts sometimes as he has less power than the Constitution gives him.

  6. Malaria in pregnancy; facts from the parasitology laboratory: a ten-year study in Abuja, North Central Nigeria

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    Ibecheozor, N.K.O

    2014-09-01

    Full Text Available Malaria, which is transmitted by female Anopheles mosquitoes, is the major cause of mortality among the pregnant women in the sub-Saharan Africa. A ten year study of malaria in pregnancy was carried out in Abuja, North Central Nigeria. Thick and thin blood films were stained with the Giemsa methodology. Of the 16760 pregnant women blood samples, 4571 (27.3% were positive for malaria parasites caused by Plasmodium falciparum. Of the 4571 positive cases, 75 (1.7% had parasite density of >5000 parasites/µl of blood; 148 (3.2% had between 500-5000 parasites/µl of blood; 520 (11.4% had between 50 - 500 parasites/µl of blood; while 3828 (83.7% had between 5-50 parasites/µl of blood. With the current estimate of over 4500 deaths of pregnant women in Nigeria due to malaria annually, we must make deliberate efforts to stop these unacceptable and painful losses. The continued use of malaria rapid diagnostic tests (M-RDTs methodologies should be discontinued because of its negative implications. Therefore, the microscopic laboratory diagnostic component should be included in ANC at all level of health care facility.

  7. Resistance of herpes simplex viruses to acyclovir: an update from a ten-year survey in France.

    Science.gov (United States)

    Frobert, Emilie; Burrel, Sonia; Ducastelle-Lepretre, Sophie; Billaud, Geneviève; Ader, Florence; Casalegno, Jean-Sébastien; Nave, Viviane; Boutolleau, David; Michallet, Mauricette; Lina, Bruno; Morfin, Florence

    2014-11-01

    The widespread use of acyclovir (ACV) and the increasing number of immunocompromised patients have raised concern about an increase in ACV-resistant herpes simplex virus (HSV). ACV resistance has traditionally been a major concern for immunocompromised patients with a frequency reported between 2.5% and 10%. The aim of this study was to reassess the status of HSV resistance to ACV in immunocompetent and immunocompromised patients over a ten year period, between 2002 and 2011. This was done by retrospectively following 1425 patients. In immunocompetent patients, prevalence of resistance did not exceed 0.5% during the study period; whereas in immunocompromised patients, a significant increase was observed, rising from 3.8% between 2002 and 2006 (7/182 patients) to 15.7% between 2007 and 2011 (28/178) (p=0.0001). This sharp rise in resistance may largely be represented by allogeneic hematopoietic stem cell transplant patients, in which the prevalence of ACV resistance rose similarly from 14.3% (4/28) between 2002 and 2006 to 46.5% (26/56) between 2007 and 2011 (p=0.005). No increase in ACV resistance was detected in association with other types of immune deficiencies. Genotypic characterization of HSV UL23 thymidine kinase and UL30 DNA polymerase genes revealed 11 and 7 previously unreported substitutions, respectively. These substitutions may be related to potential polymorphisms, drug resistance, or other mutations of unclear significance. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. Do Karst Rivers “deserve” their own biotic index? A ten years study on macrozoobenthos in Croatia

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    Rađa Biljana

    2010-07-01

    Full Text Available In this study we present the results of a ten year survey of the aquatic macroinvertebrate fauna along four karst rivers: Jadro, Žrnovnica, Grab and Ruda, all of them situated in the Middle Dalmatia region of Croatia, in an attempt to construct the Iliric Biotic Index, which will be more applicable for the water quality analysis than the most frequently applied biotic index in Croatia, the Italian Modification of Extended Biotic Index. The rivers geologically belong to the Dinaric karst, unique geological phenomena in Europe. Benthic macroinvertebrates were collected along each river at 15 sites by standard methods of sampling along with several physicochemical parameters, including: temperature, dissolved oxygen, carbon dioxide, alkalinity, hardness and pH. Univariate and multivariate techniques revealed differences in the macroinvertebrate community structure as well as in physicochemical parameters between the Karst rivers and continental rivers. Based on those differences, the Iliric Biotic Index was proposed as the standard of karst river water quality in Croatia in accordance with the EU Water Framework Directive. Differences between the Iliric Biotic Index and the most commonly used biotic indices in the European Community and the USA (The Biological Monitoring Working Party (B.M.W.P. scores, i.e. Extended Biotic Index, Indice Biotique, Family Biotic Index suggest that karst rivers need a new biotic index.

  9. 30 years after Chernobyl. What would we make better today?; 30 Jahre nach Tschernobyl. Was wuerden wir heute besser machen?

    Energy Technology Data Exchange (ETDEWEB)

    Bieringer, Jacqueline [Bundesamt fuer Strahlenschutz, Freiburg (Germany). Fachgebiet SW 2.5; Hajek, Michael [Oesterreichischer Verband fuer Strahlenschutz, Wien (Austria). Vienna International Centre; Maringer, Franz Josef [BEV - Bundesamt fuer Eich- und Vermessungswesen, Wien (Austria). Referat fuer ionisierende Strahlung und Radioaktivitaet; Murith, Christophe [Bundesamt fuer Gesundheit (BAG), Bern (Switzerland). Abt. Strahlenschutz; Steinkopff, Thomas [Deutscher Wetterdienst, Offenbach (Germany); Wershofen, Herbert [Physikalisch-Technische Bundesanstalt, Braunschweig (Germany). Lab. 6.301; Hefner, Alfred; Maushart, Rupprecht; Steger, Ferdinand

    2016-05-01

    The reactions of the authorities responsible for the measurements of radioactivity in the environment in Germany, Switzerland and Austria ore shown. The further development of the readiness and the possibilities to measure in the last 30 years are described. Also the question of activity measurements after a nuclear accident by single members of the population is dealt with.

  10. Clinical diagnosis of syphilis: a ten-year retrospective analysis in a South Australian urban sexual health clinic.

    Science.gov (United States)

    Forrest, C E; Ward, A

    2016-12-01

    National notifications for infectious syphilis in Australia have increased in recent years. Outside of sexual health clinics, junior clinicians seldom encounter this disease in its infectious stage (primary, secondary and early latent). With such a variable clinical presentation, textbook teaching is no substitute for real-life experience. The importance of accurate classification and staging of disease is relevant to the risk of transmission and determines treatment duration. In this article, the authors review the clinical presentation of syphilis over ten years in an urban sexual health clinic with a focus on the clinical presentation and diagnosis of infectious syphilis, in particular secondary syphilis, compared with that outlined in the Australian National Notifiable Diseases Surveillance System guidelines. This retrospective review of all patients diagnosed with syphilis at an urban sexual health clinic showed that between 2005 and 2015, 226 cases of syphilis were diagnosed. Documentation of impression of clinical staging of disease was present in 46% of the cases. Seventeen of these cases were recorded as secondary syphilis. The criteria used by clinicians to diagnose the secondary syphilis cases were consistent with criteria defined by the Australian National Notifiable Diseases Surveillance System. All cases of secondary syphilis had at least one cutaneous manifestation of disease. The demographic of the cohort of syphilis cases was consistent with that recorded in the literature. This review showed that the clinician's diagnosis of secondary syphilis in this service is consistent with the National Notifiable Diseases Surveillance System guidelines. Continuing education of junior medical staff is important to facilitate diagnosis and improve documentation of clinical staging, minimise disease transmission and ensure appropriate treatment. © The Author(s) 2016.

  11. Dying from cancer or other chronic diseases in the Netherlands: ten-year trends derived from death certificate data

    Directory of Open Access Journals (Sweden)

    Hingstman Lammert

    2009-02-01

    Full Text Available Abstract Background For the further development of palliative care, it is relevant to gain insight into trends in non-acute mortality. The aim of this article is twofold: (a to provide insight into ten-year trends in the characteristics of patients who died from cancer or other chronic diseases in the Netherlands; (b to show how national death statistics, derived from physicians' death certificates, can be used in this type of investigations. Methods Secondary analysis of data from 1996 to 2006 on the "primary" or "underlying" cause of death from official death certificates filled out by physicians and additional data from 2003 to 2006 on the place of death from these certificates. Results Of the 135,000 people who died in the Netherlands in 2006, 77,000 (or 57% died from a chronic disease. Cancer was the most frequent cause of death (40,000. Stroke accounted for 10,000 deaths, dementia for 8,000 deaths and COPD and heart failure each accounted for 6,000 deaths. Compared to 1996, the number of people who died from chronic diseases has risen by 6%. Of all non-acute deaths, almost three quarters were at least 70 years old when they died. Almost one third of the people died at home (31%, 28% in a hospital, 25% in a nursing home and 16% somewhere else. Conclusion Further investments to facilitate dying at home are desirable. Death certificate data proved to be useful to describe and monitor trends in non-acute deaths. Advantages of the use of death certificate data concern the reliability of the data, the opportunities for selection on the basis of the ICD-10, and the availability and low cost price of the data.

  12. Preparing for the future today: The findings of the NEA RK and M initiative for the short term (This period covers several decades and likely more than 100 years. The actual duration will vary across national programmes)

    International Nuclear Information System (INIS)

    Schroeder, Jantine

    2015-01-01

    The NEA initiative on Records, Knowledge and Memory (RK and M) across Generations is an initiative that expresses, supports and aims to answer to an evolution in long-term radioactive waste management (RWM) thinking over the past decades. In the earlier days, the vision seems to have been that waste management ends with the closure of disposal sites. Oversight after closure was not an issue that was studied, (tacitly) assuming safe oblivion of geological repositories, or that archives, markers and other similar tools would suffice, e.g. to avoid human intrusion and/or to understand the nature of the underground facility. Today, it is recognised that oversight should take place for as long as practicable. The new vision includes the preservation of information to be used by future generations. In this paper we want to highlight that such a vision shift with regard to the future requires an accompanying shift with regard to present thinking and practices. To this aim, we will outline some of the studies undertaken within the RK and M initiative that substantiate this finding that the future starts today, and offer suggestions to support its concretization. societal oversight as long as practicable, we should acknowledge the fact that RK and M loss takes place rapidly if it is not acted upon in a conscious and ongoing manner that involves various actors and does more than dumping records into archives. The success of RK and M preservation cannot be judged today by whether they will last for one or ten thousand years. Instead, it lies in establishing and maintaining awareness of the need and responsibility for RK and M preservation in the minds of regulators, operators, stakeholders and, especially in the longer term, the local and regional authorities and general public. Therefore, we should not only think about future activities, but act upon the idea that the long term starts today, and that RK and M preservation needs to be prepared for in the present, while the

  13. Ten Utah Painters

    OpenAIRE

    Whitlock, Andrew

    1984-01-01

    Today the art world is rich and diverse with regional as well as national art centers. As in the past, art is alive and well in Utah. The show Ten Utah Painters invites us to see and experiece what some of Utah's best contemporary artists are doing. Their paintings invite us to look and to enjoy but also to learn and open up our visual senses to a broader vista.

  14. A Ten-Year Global Record of Absorbing Aerosols Above Clouds from OMI's Near-UV Observations

    Science.gov (United States)

    Jethva, Hiren; Torres, Omar; Ahn, Changwoo

    2016-01-01

    Aerosol-cloud interaction continues to be one of the leading uncertain components of climate models, primarily due to the lack of an adequate knowledge of the complex microphysical and radiative processes associated with the aerosol-cloud system. The situations when aerosols and clouds are found in the same atmospheric column, for instance, when light-absorbing aerosols such as biomass burning generated carbonaceous particles or wind-blown dust overlay low-level cloud decks, are commonly found over several regional of the world. Contrary to the cloud-free scenario over dark surface, for which aerosols are known to produce a net cooling effect (negative radiative forcing) on climate, the overlapping situation of absorbing aerosols over cloud can potentially exert a significant level of atmospheric absorption and produces a positive radiative forcing at top-of-atmosphere. The magnitude of direct radiative effects of aerosols above cloud depends directly on the aerosol loading, microphysical-optical properties of the aerosol layer and the underlying cloud deck, and geometric cloud fraction. We help in addressing this problem by introducing a novel product of optical depth of absorbing aerosols above clouds retrieved from near-UV observations made by the Ozone Monitoring Instrument (OMI) on board NASA's Aura platform. The presence of absorbing aerosols above cloud reduces the upwelling radiation reflected by cloud and produces a strong 'color ratio' effect in the near-UV region, which can be unambiguously detected in the OMI measurements. Physically based on this effect, the OMACA algorithm retrieves the optical depths of aerosols and clouds simultaneously under a prescribed state of atmosphere. The algorithm architecture and results from a ten-year global record including global climatology of frequency of occurrence and above-cloud aerosol optical depth, and a discussion on related future field campaigns are presented.

  15. [Ten years experience with the first approved biosimilar recombinant human growth hormone drug in normal clinical practice].

    Science.gov (United States)

    López-Siguero, Juan Pedro; Palla García, Margarida; Martínez Busto, Elena; Rebollo, Francisco José; Pombo, Manuel

    2017-06-28

    Recombinant human growth hormone (rhGH) is the first biosimilar drug approved by the European Medicines Agency in 2006, using the biosimilar registration process. It was authorised for the treatment of growth hormone deficiency, and growth disorders associated with Turner's syndrome, chronic renal failure, Prader-Willi syndrome, and growth disorders in children/adolescents born small for gestational age, and replacement therapy in adults with pronounced growth hormone deficiency. This review is focused on the scientific evidence published about this drug in the last ten years, including the clinical trials on which the approval of the regulatory authority is based, and the most relevant studies evaluating the clinical impact of the drug in clinical practice. The equivalence between biosimilar and original product has been confirmed in the clinical trials published by Romer et al. and López-Siguero et al. Furthermore, studies carried out in real-life conditions confirm its long-term efficacy and safety, as well as the absence of clinical impact by switching treatment from the original to the biosimilar product. The number of patients receiving this medication has continuously increased since its approval. Its equivalence with the original product has been verified. Preliminary data from the post-authorisation PATRO study confirm the efficacy and safety of the biosimilar product in comparison with data from clinical trials. However, final results must be evaluated at the end of the study, which will provide additional information about the long-term efficacy and safety of the biosimilar drug. Copyright © 2017. Publicado por Elsevier España, S.L.U.

  16. Resilience research and policy/practice discourse in health, social, behavioral, and environmental sciences over the last ten years.

    Science.gov (United States)

    Almedom, Astier M

    2008-12-01

    Resilience research has gained increased scientific interest and political currency over the last ten years. To set this volume in the wider context of scholarly debate conducted in previous special theme issue and/or special section publications of refereed journals on resilience and related concepts (1998-2008). Peer reviewed journals of health, social, behavioral, and environmental sciences were searched systematically for articles on resilience and/or related themes published as a set. Non-English language publications were included, while those involving non-human subjects were excluded. A total of fifteen journal special issues and/or special sections (including a debate and a roundtable discussion) on resilience and/or related themes were retrieved and examined with the aim of teasing out salient points of direct relevance to African social policy and health care systems. Viewed chronologically, this series of public discussions and debates charts a progressive paradigm shift from the pathogenic perspectives on risk and vulnerability to a clear turn of attention to health-centered approaches to building resilience to disasters and preventing vulnerability to disease, social dysfunction, human and environmental resource depletion. Resilience is a dynamic and multi-dimensional process of adaptation to adverse and/or turbulent changes in human, institutional, and ecological systems across scales, and thus requires a composite, multi-faceted Resilience Index (RI), in order to be meaningfully gauged. Collaborative links between interdisciplinary research institutions, policy makers and practitioners involved in promoting sustainable social and health care systems are called for, particularly in Africa.

  17. Monitoring of Pb exposure in waterfowl ten years after a mine spill through the use of noninvasive sampling.

    Directory of Open Access Journals (Sweden)

    Monica Martinez-Haro

    Full Text Available Lead exposure in waterfowl was studied using noninvasive fecal sampling in the Guadalquivir Marshes in Spain, an area affected by the 1998 Aznalcóllar mine disaster. Feces of greylag geese (Anser anser, n = 191 and purple gallinule (Porphyrio porphyrio, n = 91 were collected from three different impacted sites (Entremuros, Caracoles and Cerro de los Ánsares during the winters of 2004 to 2008. Lead and aluminium (an indicator of sediment ingestion and Pb isotope signatures (to discriminate between sources of Pb exposure were analyzed in freeze-dried, acid digested samples. The concentrations of fecal porphyrins and biliverdin were determined as noninvasive biomarkers to study Pb exposure effects. Results showed a decrease in Pb exposure over time in wintering greylag geese. In contrast, for purple gallinule resident in the Entremuros a clear trend was not evident. For both species, sediment ingestion appeared to be the main source of exposure to Pb. In the Entremuros, some samples from purple gallinule were detected with higher Pb levels than expected for simple soil ingestion, and these had Pb isotopic profiles compatible with mining sludge or Pb shot. Whilst fecal Pb isotopic profiles were effective in differentiating between samples from sites with different levels and sources of pollution, the combined use of element ratios (such as Pb/Al and other non-traditional stable isotope signatures may also prove worthwhile. Overall, the fecal Pb levels detected were below those described in feces for waterfowl from other uncontaminated areas(<10 µg/g d.w.. Despite this, for both species fecal Pb levels were positively correlated with porphyrin excretion, and for purple gallinule, with the coproporphyrin III/I ratio, suggesting some subtle effects on heme synthesis in birds. Ten years after the mine spill, Pb contamination in birds by this pollution source was still detectable and subtlethal effects may persist.

  18. Antecedents of Screening Positive for Attention Deficit Hyperactivity Disorder in Ten-Year-Old Children Born Extremely Preterm.

    Science.gov (United States)

    Leviton, Alan; Hooper, Stephen R; Hunter, Scott J; Scott, Megan N; Allred, Elizabeth N; Joseph, Robert M; O'Shea, T Michael; Kuban, Karl

    2018-04-01

    The incidence of attention deficit hyperactivity disorder is higher among children born very preterm than among children who are mature at birth. We studied 583 ten-year-old children who were born before 28 weeks of gestation whose IQ was above 84 and had a parent-completed Child Symptom Inventory-4, which allowed classification of the child as having or not having symptoms of attention deficit hyperactivity disorder. For 422 children, we also had a teacher report, and for 583 children, we also had a parent report of whether or not a physician made an attention deficit hyperactivity disorder diagnosis. The risk profile of screening positive for attention deficit hyperactivity disorder based on a parent's report differed from the risk profile based on the teacher's report, whereas the risk profile according to a physician and according to any two observers closely resembled the parent-reported profile. Among the statistically significant risk factors were young maternal age (parent, physician, and two observers), maternal obesity (parent, physician, and two observers), maternal smoking (parent, physician, and two observers), magnesium given at delivery for seizure prophylaxis (parent and two observers), recovery of Mycoplasma sp. from the placenta (teacher and two observers), low gestational age (parent and two observers), low birth weight (teacher and physician), singleton (parent, physician, and two observers), male (parent, teacher, physician, and two observers), mechanical ventilation on postnatal day seven (physician), receipt of a sedative (parent and two observers), retinopathy of prematurity (parent), necrotizing enterocolitis (physician), antibiotic receipt (physician and two observers), and ventriculomegaly on brain scan (parent and two observers). The multiplicity of risk factors identified can be subsumed as components of four broad themes: low socioeconomic state, immaturity or vulnerability, inflammation, and epigenetic phenomena. Copyright © 2017

  19. Monitoring of Pb Exposure in Waterfowl Ten Years after a Mine Spill through the Use of Noninvasive Sampling

    Science.gov (United States)

    Martinez-Haro, Monica; Taggart, Mark A.; Lefranc, Hugues; Martín-Doimeadiós, Rosa C.; Green, Andy J.; Mateo, Rafael

    2013-01-01

    Lead exposure in waterfowl was studied using noninvasive fecal sampling in the Guadalquivir Marshes in Spain, an area affected by the 1998 Aznalcóllar mine disaster. Feces of greylag geese (Anser anser, n = 191) and purple gallinule (Porphyrio porphyrio, n = 91) were collected from three different impacted sites (Entremuros, Caracoles and Cerro de los Ánsares) during the winters of 2004 to 2008. Lead and aluminium (an indicator of sediment ingestion) and Pb isotope signatures (to discriminate between sources of Pb exposure) were analyzed in freeze-dried, acid digested samples. The concentrations of fecal porphyrins and biliverdin were determined as noninvasive biomarkers to study Pb exposure effects. Results showed a decrease in Pb exposure over time in wintering greylag geese. In contrast, for purple gallinule resident in the Entremuros a clear trend was not evident. For both species, sediment ingestion appeared to be the main source of exposure to Pb. In the Entremuros, some samples from purple gallinule were detected with higher Pb levels than expected for simple soil ingestion, and these had Pb isotopic profiles compatible with mining sludge or Pb shot. Whilst fecal Pb isotopic profiles were effective in differentiating between samples from sites with different levels and sources of pollution, the combined use of element ratios (such as Pb/Al) and other non-traditional stable isotope signatures may also prove worthwhile. Overall, the fecal Pb levels detected were below those described in feces for waterfowl from other uncontaminated areas(fecal Pb levels were positively correlated with porphyrin excretion, and for purple gallinule, with the coproporphyrin III/I ratio, suggesting some subtle effects on heme synthesis in birds. Ten years after the mine spill, Pb contamination in birds by this pollution source was still detectable and subtlethal effects may persist. PMID:23437364

  20. Ten years of health workforce planning in the Netherlands: a tentative evaluation of GP planning as an example

    Directory of Open Access Journals (Sweden)

    Van Greuningen Malou

    2012-08-01

    Full Text Available Abstract Introduction In many countries, health-care labour markets are constantly being challenged by an alternation of shortage and oversupply. Avoiding these cyclic variations is a major challenge. In the Netherlands, a workforce planning model has been used in health care for ten years. Case description Since 1970, the Dutch government has explored different approaches to determine the inflow in medical schools. In 2000, a simulation model for health workforce planning was developed to estimate the required and available capacity of health professionals in the Netherlands. In this paper, this model is explained, using the Dutch general practitioners as an example. After the different steps in the model are clarified, it is shown how elements can be added to arrive at different versions of the model, or ‘scenarios’. A comparison is made of the results of different scenarios for different years. In addition, the subsequent stakeholder decision-making process is considered. Discussion and evaluation Discussion of this paper shows that workforce planning in the Netherlands is a complex modelling task, which is sensitive to different developments influencing the balance between supply and demand. It seems plausible that workforce planning has resulted in a balance between supply and demand of general practitioners. Still, it remains important that the modelling process is accepted by the different stakeholders. Besides calculating the balance between supply and demand, there needs to be an agreement between the stakeholders to implement the advised training inflow. The Dutch simulation model was evaluated using six criteria to be met by models suitable for policy objectives. This model meets these criteria, as it is a comprehensive and parsimonious model that can include all relevant factors. Conclusion Over the last decade, health workforce planning in the Netherlands has become an accepted instrument for calculating the required supply of

  1. The Result of The Treatment of Infantile Spasm After Two Year Follow-Up Review Of 45 Cases in Ten Past Years

    Directory of Open Access Journals (Sweden)

    A Nasirian

    2001-06-01

    Full Text Available In the past ten years, 45 cases of infantile spasm treated in our center. From these patients, 15 cases received only steroid, other 15 cases only clonazepam, and the rest, a combination of clonazepam and steroid. All patients were observed for two years. This is a retrospective study, the data being extracted from patients record. A number of patients were treated in ambulatory and the others were patients of the hospital. The result of comparison of optimal control of seizures are as follow: 1 In only steroid group 27 percent of the patients were free of seizure, 2 In only clonazepam group 28 percent showed no seizure, 3 in combined clonazepam and steroid group 39% were seizure-free. Based on this trial we believe that treatment of infantile spasm with combined steroid and clonazepam is better than any of them alone. Considering these results, we believe that the treatment of infantile spasm with a combination of steroid and clonazepam is preferable to these drugs.

  2. Seventh report of the ten on the Swiss electrical economy: endangered supply in the next 20 years

    International Nuclear Information System (INIS)

    Anon.

    1987-01-01

    The seventh report of the ten major companies in the Swiss electric industry is discussed. The report predicts that, even with the addition of the Kaiseraugst nuclear power station, there will be a deficit in the supply of electricity compared with demand of some 4 milliards kWh by the winter of 2004/2005

  3. Distribution and trends in outpatient utilization of generic versus brand name psychopharmaceuticals during a ten-year period in Croatia.

    Science.gov (United States)

    Polić-ViŽintin, Marina; Stimac, Danijela; Sostar, Zvonimir; Tripković, Ingrid

    2014-08-15

    Drug costs increasingly pose a burden upon the otherwise inadequate health care resources and rational drug utilization is an important segment of every national health policy. Optimal patient care should be the goal of rational pharmacotherapy, whereby the economic burden of treatment is just one of the elements to be considered on choosing appropriate therapy.The aim of this study was to determine distribution and trends in the outpatient utilization of generic versus brand name psychopharmaceuticals and to evaluate the rationality of prescribing psychopharmaceuticals during a ten-year period. Using the World Health Organization Anatomical-Therapeutic-Chemical classification/Defined Daily Doses (ATC/DDD) methodology, the number of DDD was calculated from data collected from pharmacies on the number and size of drug packages. The ratio of generic and brand name drug costs served as an indicator on assessing the rationality of drug utilization. Total cost for psychopharmaceuticals increased by 20.1%, more for brand name than for generic agents (32.7% vs. 7.4%). The highest share of generic psychopharmaceuticals as compared with brand name drugs according to DDD per 1000 inhabitants per day (DDD/1000/day) was in the group of psycholeptics (83.6% in 2001 vs. 82.2% in 2010), most in hypnotics and sedatives, and least in antipsychotics. The share of generic psychopharmaceuticals in total drug utilization according to financial indicators decreased by 9.6% and according to DDD/1000/day by 12%. The greatest decrease was in antidepressants, i.e. by 33.8% according to financial indicators and by 46% according to DDD/1000/day; and in antipsychotics by 30.9% according to DDD/1000/day, while showing an increase by 8.5% according to financial indicators. In the therapeutic subgroup of mood stabilizers, the share of generic drugs in total drug utilization declined by 32% according to DDD/1000/day, but increased by 25.1% according to financial indicators. The lack of uniform

  4. HIPs at Ten

    Science.gov (United States)

    Kuh, George; O'Donnell, Ken; Schneider, Carol Geary

    2017-01-01

    2017 is the anniversary of the introduction of what are now commonly known as high-impact practices (HIPs). Many of the specific activities pursued under the HIPs acronym have been around in some form for decades, such as study abroad, internships, and student-faculty research. It was about ten years ago that, after conferring HIPs at Ten with…

  5. The ten-year course of depression in primary care and long-term effects of psychoeducation, psychiatric consultation and cognitive behavioral therapy

    NARCIS (Netherlands)

    Conradi, H.J.; Bos, E.H.; Kamphuis, J.H.; de Jonge, P.

    2017-01-01

    Background While the majority of depressed patients are treated in primary care, long-term follow-up data on the naturalistic course of depression and treatment effectiveness in this setting are scarce. This study examined the ten-year course of depression in primary care patients who had

  6. The ten-year course of depression in primary care and long-term effects of psychoeducation, psychiatric consultation and cognitive behavioral therapy

    NARCIS (Netherlands)

    Conradi, Henk Jan; Bos, Elisabeth H; Kamphuis, Jan H; de Jonge, Peter

    BACKGROUND: While the majority of depressed patients are treated in primary care, long-term follow-up data on the naturalistic course of depression and treatment effectiveness in this setting are scarce. This study examined the ten-year course of depression in primary care patients who had

  7. OYSTER POPULATUION ESTIMATION IN SUPPORT OF THE TEN-YEAR GOAL FOR OYSTER RESOTRATION IN THE CHESAPEAKE BAY: DEVELOPING STRATEGIES FOR RESTORING AND MANAGING THE EASTERN OYSTER

    Science.gov (United States)

    Mann, Roger, Steve Jordan, Gary Smith, Kennedy Paynter, James Wesson, Mary Christman, Jessica Vanisko, Juliana Harding, Kelly Greenhawk and Melissa Southworth. 2003. Oyster Population Estimation in Support of the Ten-Year Goal for Oyster Restoration in the Chesapeake Bay: Develop...

  8. Let Book Joy Begin @ Your Library[R]!: Ten Years of El Dia de los Ninos/El Dia de los Libros

    Science.gov (United States)

    Roy, Loriene

    2007-01-01

    Ten years ago, in 1996, poet and children's book author, Pat Mora began celebrating "book joy" by founding a children's book and reading day, El Dia de los Ninos/El Dia de los Libros or Children's Day/Book Day. Dia is modeled on National Children's Day Celebrations in Mexico held since 1925 when it was launched in conjunction with a…

  9. Students' Constitutional Right to a Sound Basic Education: New York State's Unfinished Agenda. Part 1. A Roadmap to Constitutional Compliance Ten Years after "CFE v. State"

    Science.gov (United States)

    Rebell, Michael A.; Wolff, Jessica R.

    2016-01-01

    Ten years have passed since New York's highest court ruled in the landmark school-funding and educational-rights case, "Campaign for Fiscal Equity (CFE) v. State of New York," that the state was violating students' constitutional right to the "opportunity for a sound basic education" and ordered significant reforms of the…

  10. Ten-year follow-up study of three alternative bearing surfaces used in total hip arthroplasty in young patients: a prospective randomised controlled trial.

    Science.gov (United States)

    Atrey, A; Ward, S E; Khoshbin, A; Hussain, N; Bogoch, E; Schemitsch, E H; Waddell, J P

    2017-12-01

    We present the ten-year data of a cohort of patients, aged between 18 and 65 years (mean age 52.7 years; 19 to 64), who underwent total hip arthroplasty. Patients were randomised to be treated with a cobalt-chrome (CoCr) femoral head with an ultra-high molecular weight polyethylene (UHMWPE), highly cross-linked polyethylene (XLPE) or ceramic-on-ceramic (CoC) bearing surface. A total of 102 hips (91 patients) were randomised into the three groups. At ten years, 97 hips were available for radiological and functional follow-up. Two hips (two patients) had been revised (one with deep infection and one for periprosthetic fracture) and three were lost to follow-up. Radiological analysis was performed using a validated digital assessment programme to give linear, directional and volumetric wear of the two polyethylene groups. There was a significantly reduced rate of steady-state linear wear with XLPE (0.07 mm/yr) compared with UHMWPE (0.37 mm/yr) (p = 0.001). Volumetric wear was also significantly reduced in the XLPE group (29.29 mm 3 /yr) compared with the UHMWPE group (100.75mm 3 /yr) (p = 0.0001). There were six patients with UHMWPE who had non-progressive osteolysis and none in the XLPE group. All three bearing groups had significant improvements in 12-item short form health survey scores, Western Ontario and McMaster Universities Osteoarthritis Index score and Harris Hip Score. However, the improvement in HSS was significantly less in the UHMWPE group (p = 0.0188) than in the other two groups. At ten years, the rates of volumetric and linear wear in the XLPE group remain low and predominantly below the estimated threshold for osteolysis (1 mm/yr). The rate of linear wear in the XLPE group was three times less than in the UHMWPE group at five-year follow-up and five times less at ten years. The rate of volumetric wear was also three times less in the XLPE group at ten years. While CoC also performs well, XLPE at ten years remains a safe and excellent bearing option

  11. Surgical treatment of thoraco-abdominal and low thoracic aneurysms of the aorta. One single center experience over ten years

    OpenAIRE

    El Arid, J.-M.; CREEMERS, Etienne; Limet, Raymond

    2006-01-01

    This work presents the results of surgery in thoraco-abdominal aortic aneurysms (TAA) and thoracic descending aortic aneurysms (TDA) in one single center between January 1rst, 1996 and December 31, 2005. It concerns open surgery in 42 and endovascular procedures in ten patients. Forty two patients (11 TDA and 31 TAA (4 type I, 12 type II, 6 type III and 9 type IV)) define the open surgery series. Twenty six patients were operated on elective basis and 16 patients in emergency condition. Surgi...

  12. A synthesis of ten years' tests on scale models of LMFBR steam generators at the CGVS facility

    International Nuclear Information System (INIS)

    Fontaine, J.P.; Quinet, J.L.

    1982-01-01

    Electricite de France has built a high power sodium heated steam generator (SG) facility (CGVS), capable of reproducing all possible operating conditions, to study the behaviour of scale-models of industrial apparatuses. The main findings of the experiments were as follows: - heat exchange surfaces remained perfectly leak proof; - hydrogen detection in the sodium and argon constitute additional systems for monitoring the impermeability to leaks of a SG with a free sodium surface; - extrapolation of the findings to the SUPER PHENIX SG shows that water leaking at a rate of 100 mg/s would induce in ten minutes a 50% rise of the signal produced by the hydrogen monitoring device in the sodium; - acoustic method can detect leaks of the order of one g/s in a 45 MW SG sited in an industrial environment

  13. Today's threat and tomorrow's reaction

    International Nuclear Information System (INIS)

    Moore, L.R.

    2002-01-01

    Full text: The events of September 11 have only confirmed our past nightmares and warnings to industries, agencies, and governments. The threat of even more significant catastrophic attacks, using nuclear materials, was just as real ten years ago, as it is today. In many cases, our vulnerability remains the same as years ago. There is a dire need for all organizations to agree upon threats and vulnerabilities, and to implement appropriate protections, for nuclear materials or other 'means' to achieve an event of mass destruction. All appropriate organizations (industries, agencies, and governments) should be able to define, assess, and recognize international threats and vulnerabilities in the same manner. In complimentary fashion, the organizations should be able to implement safeguards against this consistent generic threat. On an international scale the same threats, and most vulnerabilities, pose high risks to all of these organizations and societies. Indeed, in today's world, the vulnerabilities of one nation may clearly pose great risk to another nation. Once threats and vulnerabilities are consistently recognized, we can begin to approach their mitigation in a more 'universal' fashion by the application of internationally recognized and accepted security measures. The path to recognition of these security measures will require agreement on many diverse issues. However, once there is general agreement, we can then proceed to the acquisition of diverse national and international resources with which to implement the security measures 'universally' to eliminate 'weak-links' in the chain of nuclear materials, on a truly international scale. I would like to discuss: developing a internationally acceptable 'generic' statement of threat, vulnerability assessment process, and security measure; proposing this international statement of threat, vulnerability assessment process, and appropriate security measures to organizations (industries, agencies, and governments

  14. Waves and turbulences studies in plasmas: ten years of research on quiescent plasmas at the Brazilian Space Research National Institute

    International Nuclear Information System (INIS)

    Ferreira, J.L.

    1991-01-01

    Quiescent plasmas generated by thermionic discharges and surface confined by multipole magnetic fields have been used in basic plasma research since 1973. The first machine was developed at UCLA (USA) to produce an uniform plasma for beam and waves studies in large cross section plasmas. A double quiescent plasma machine was constructed at the plasma laboratory of INPE in 1981, it began its operation producing linear ion-acoustic waves in an Argon plasma. Later on non linear ion acoustic waves and solitons were studied in plasma containing several species of negative and positive ions. The anomalous particle transport across multipole magnetic fields were also investigated. An anomalous resistivity associated with an ion acoustic turbulence is responsible for the formation of a small amplitude double-layer. The existence of a bootstrap mechanism is shown experimentally. Today, the main interest is toward the generation of Langmuir waves in non uniform plasmas. An experimental study on Langmuir wave generation using a grid system is been carried on. A magnetized quiescent plasma device for studies of whistle wave generation is been constructed. This machine will make possible future studies on several wave modes of magnetized plasmas. (author). 31 refs, 16 figs

  15. History of radiation protection in the Czech Republic. Ten years of the National Radiation Protection Institute, 1995-2005

    International Nuclear Information System (INIS)

    Drabkova, A.

    2006-01-01

    The first part of the publication, highlighting the history of radiation protection in the country which today is the Czech Republic, is divided into the following sections: Inception of the field of science and applications 'Protection from ionizing radiation'; Beginnings of work with ionizing radiation in the Czech lands; Formulation of the first health physics and radiation protection requirements in the Czech lands; Beginnings of institutionalization of radiation protection in Czechoslovakia after World War II; The Clinic and Institute of Occupational Medicine in Prague; Institute of Occupational Hygiene and Occupational Diseases in Prague and the regional Institute of Occupational Hygiene and Occupational Diseases in Bratislava; Peaceful uses of atomic energy in Czechoslovakia; First man-made radioisotopes in Czechoslovakia; Health rules and standards applicable to work with ionizing radiation; The responsibilities of the Ministry of Health in the area of health physics and radiation protection within peaceful uses of atomic energy in the Czech Socialist Republic; Research Institute of Health Physics; Institute of Occupational Hygiene and Prevention of Occupational Diseases in the Mining and Processing of Radioactive Raw Materials; Health physics and radiation protection in sectorial and national research plans; Health Physics Centre, Institute of Hygiene and Epidemiology; National Radiation Protection Institute (as a subsidiary of the State Office for Nuclear Safety). The second part of the publication gives details of the recent history of the National Radiation Protection Institute. (P.A.)

  16. Ten Top Films for Teaching about China Today

    Science.gov (United States)

    Lee, Tanya

    2010-01-01

    As it becomes increasingly essential to include China in the social studies curriculum, teachers are faced with the challenges of finding appropriate, high-quality resources, and, more fundamentally, of engaging students with a culture and a place far removed from their own. Film and video can address both issues, and there is a wealth of…

  17. Secular trends: a ten-year comparison of the amount and type of physical activity and inactivity of random samples of adolescents in the Czech Republic

    OpenAIRE

    Frömel Karel; Sigmund Erik; El Ansari Walid; Sigmundová Dagmar

    2011-01-01

    Abstract Background An optimal level of physical activity (PA) in adolescence influences the level of PA in adulthood. Although PA declines with age have been demonstrated repeatedly, few studies have been carried out on secular trends. The present study assessed levels, types and secular trends of PA and sedentary behaviour of a sample of adolescents in the Czech Republic. Methods The study comprised two cross-sectional cohorts of adolescents ten years apart. The analysis compared data colle...

  18. Ten-year survival and prognostic markers in one thousand patients with advanced heart failure. A single-centre analysis.

    Science.gov (United States)

    Lesny, Peter; Luknar, Milan; Matejka, Martin; Varga, Ivan; Solik, Peter; Wimmerova, Sona; Goncalvesova, Eva

    2016-06-01

    Patients with advanced heart failure (HF) represent a pool of candidates for heart transplantation and long-term mechanical circulatory support devices. The aim of our study was to determine simple and reliable markers of one-year mortality for selection of the most suitable patients for heart replacement therapy. One thousand consecutive patients with HF (mean age 49 ± 10.9 years; 86.8% males) referred to a single tertiary centre from January 1998 to January 2010 in order to assess the indication for heart transplantation were enrolled. Kaplan-Meier survival analysis was performed. Independent mortality predictors were established using logistic regression analysis. The mean follow-up was 4.3 ± 2.7 years (range 1-12 years). Cumulative survival was as follows: 1-year survival 83%, 3-year 63%, 5-year 50%, 7-year 39%, and 10-year 23%. Independent predictors of 1-year mortality included coronary artery disease, left ventricular diastolic diameter >79 mm, plasma sodium 240 mg/day. Short-term prognosis of HF patient can be estimated based on simple parameters. Patients with signs of poor prognosis should be referred to tertiary centres to be considered for heart replacement therapy.

  19. Paper 4 : EUROCAT Statistical Monitoring: Identification and Investigation of Ten Year Trends of Congenital Anomalies in Europe

    NARCIS (Netherlands)

    Loane, Maria; Dolk, Helen; Kelly, Alan; Teljeur, Conor; Greenlees, Ruth; Densem, James

    BACKGROUND: As part of EUROCAT's surveillance of congenital anomalies in Europe, a statistical monitoring system has been developed to detect recent clusters or long-term (10 year) time trends. The purpose of this article is to describe the system for the identification and investigation of 10-year

  20. Ten-year risk-rating systems for California red fir and white fir: development and use

    Science.gov (United States)

    George T. Ferrell

    1989-01-01

    Logistic regression equations predicting the probability that a tree will die from natural causes--insects, diseases, intertree competition--within 10 years have been developed for California red fir (Abies magnifica) and white fir (A. concolor). The equations, like those with a 5-year prediction period already developed for these...

  1. Temporal Consistency Between Gross Primary Production and Solar-Induced Chlorophyll Fluorescence in the Ten Most Populous Megacity Areas over Years

    Science.gov (United States)

    Cui, Yaoping; Xiao, Xiangmin; Zhang, Yao; Dong, Jinwei; Qin, Yuanwei; Doughty, Russell B.; Zhang, Geli; Wang, Jie; Wu, Xiaocui; Qin, Yaochen; hide

    2017-01-01

    The gross primary production (GPP) of vegetation in urban areas plays an important role in the study of urban ecology. It is difficult however, to accurately estimate GPP in urban areas, mostly due to the complexity of impervious land surfaces, buildings, vegetation, and management. Recently, we used the Vegetation Photosynthesis Model (VPM), climate data, and satellite images to estimate the GPP of terrestrial ecosystems including urban areas. Here, we report VPM-based GPP (GPPvpm) estimates for the world's ten most populous megacities during 2000-2014. The seasonal dynamics of GPPvpm during 2007-2014 in the ten megacities track well that of the solar-induced chlorophyll fluorescence (SIF) data from GOME-2 at 0.5deg x 0.5deg resolution. Annual GPPvpm during 2000-2014 also shows substantial variation among the ten megacities, and year-to-year trends show increases, no change, and decreases. Urban expansion and vegetation collectively impact GPP variations in these megacities. The results of this study demonstrate the potential of a satellite-based vegetation photosynthesis model for diagnostic studies of GPP and the terrestrial carbon cycle in urban areas.

  2. Ten-Year Follow-up of the OPUS Specialized Early Intervention Trial for Patients With a First Episode of Psychosis

    DEFF Research Database (Denmark)

    Secher, Rikke Gry; Hjorthøj, Carsten Rygaard; Austin, Stephen F

    2014-01-01

    of OPUS vs treatment as usual (TAU) within an FEP cohort, 10 years after inclusion into the OPUS trial. METHODS: From 1998 to 2000, participants were randomized to OPUS or TAU. Ten years later, we conducted comprehensive interviews and performed register-based follow-up on all participants in national...... OPUS and TAU regarding income, work-related outcomes, or marital status. CONCLUSION: Most of the positive short-term effects of the OPUS intervention had diminished or vanished at this long-term follow-up. We observed a clear tendency that OPUS treatment leads to fewer days in supported housing...

  3. ProVac Global Initiative: a vision shaped by ten years of supporting evidence-based policy decisions.

    Science.gov (United States)

    Jauregui, Barbara; Janusz, Cara Bess; Clark, Andrew D; Sinha, Anushua; Garcia, Ana Gabriela Felix; Resch, Stephen; Toscano, Cristiana M; Sanderson, Colin; Andrus, Jon Kim

    2015-05-07

    The Pan American Health Organization (PAHO) created the ProVac Initiative in 2004 with the goal of strengthening national technical capacity to make evidence-based decisions on new vaccine introduction, focusing on economic evaluations. In view of the 10th anniversary of the ProVac Initiative, this article describes its progress and reflects on lessons learned to guide the next phase. We quantified the output of the Initiative's capacity-building efforts and critically assess its progress toward achieving the milestones originally proposed in 2004. Additionally, we reviewed how country studies supported by ProVac have directly informed and strengthened the deliberations around new vaccine introduction. Since 2004, ProVac has conducted four regional workshops and supported 24 health economic analyses in 15 Latin American and Caribbean countries. Five Regional Centers of Excellence were funded, resulting in six operational research projects and nine publications. Twenty four decisions on new vaccine introductions were supported with ProVac studies. Enduring products include the TRIVAC and CERVIVAC cost-effectiveness models, the COSTVAC program costing model, methodological guides, workshop training materials and the OLIVES on-line data repository. Ten NITAGs were strengthened through ProVac activities. The evidence accumulated suggests that initiatives with emphasis on sustainable training and direct support for countries to generate evidence themselves, can help accelerate the introduction of the most valuable new vaccines. International and Regional Networks of Collaborators are necessary to provide technical support and tools to national teams conducting analyses. Timeliness, integration, quality and country ownership of the process are four necessary guiding principles for national economic evaluations to have an impact on policymaking. It would be an asset to have a model that offers different levels of complexity to choose from depending on the vaccine being

  4. Weight variation in users of depot-medroxyprogesterone acetate, the levonorgestrel-releasing intrauterine system and a copper intrauterine device for up to ten years of use.

    Science.gov (United States)

    Modesto, Waleska; de Nazaré Silva dos Santos, Priscila; Correia, Vinicius Machado; Borges, Luiza; Bahamondes, Luis

    2015-02-01

    Data on record regarding weight variation in depot-medroxyprogesterone acetate (DMPA) and levonorgestrel-releasing intrauterine system (LNG-IUS) users are controversial. To date, no studies have yet evaluated weight variation in DMPA and LNG-IUS users in up to ten years of use compared to non-hormonal contraceptive users. A retrospective study analysed weight variations in 2138 women using uninterruptedly DMPA (150 mg intramuscularly, three-monthly; n = 714), the LNG-IUS (n = 701) or a copper-intrauterine device (Cu-IUD; n = 723). At the end of the first year of use, there was a mean weight increase of 1.3 kg, 0.7 kg and 0.2 kg among the DMPA-, LNG-IUS- and Cu-IUD users, respectively, compared to weight at baseline (p < 0.0001). After ten years of use, the mean weight had risen by 6.6 kg, 4.0 and 4.9 kg among the DMPA-, LNG-IUS- and Cu-IUD users, respectively. DMPA-users had gained more weight than LNG-IUS- (p = 0.0197) and than Cu-IUD users (p = 0.0294), with the latter two groups not differing significantly from each other in this respect (p = 0.5532). Users of hormonal and non-hormonal contraceptive methods gained a significant amount of weight over the years. DMPA users gained more weight over the treatment period of up to ten years than women fitted with either a LNG-IUS or a Cu-IUD.

  5. Total hip arthroplasty with dual mobility cup in osteonecrosis of the femoral head in young patients: over ten years of follow-up.

    Science.gov (United States)

    Martz, Pierre; Maczynski, Alexandre; Elsair, Sebastien; Labattut, Ludovic; Viard, Brice; Baulot, Emmanuel

    2017-03-01

    Osteonecrosis of the femoral head affects mainly young patients with high functional needs this increases the risk of dislocation. Dual mobility cups known for low rate of dislocation and high mobility range seems indicated. We evaluate functional efficiency, survival and dislocation rate of dual mobility cup for total hip arthroplasty for osteonecrosis in young patients. Monocentric retrospective clinical study, from 2000 to 2008. With a clinical analysis in pre-operative and over ten years of follow-up of one cohort of patients under 55 years old with an indication of THA for ONFH. The judgement criteria was: clinical scores at the maximal follow-up, the dislocation rate, and the cumulate survival rate over ten years follow-up. Forty THA in 31 patients, nine bilateral cases, 23 males and eight females with average age of 44 (±4) years old. In pre-operative: PMA 11 (±3.3), HHS 50,8 (±15.5). At the final follow-up of 129.8 (±33.8) months: PMA (17.4 ± 1.12), HHS (95.7 ± 6.9), no dislocation. We had 11 deaths on average at 95.2 ± 47.3 months. The cumulate survival rate over ten years follow-up is 100% without revisions or long-term dislocation. Analysis concludes to very significant functional improvement without any dislocation despite the young population with high level of activity. Thus, dual mobility cups is a reliable choice preventing dislocation with a very good survival rate without premature wear, preserving mobility and activity.

  6. Ten-Year Summary and Evaluation of Operations and Performance of the Utica Aquifer and North Lake Basin Wetlands Restoration Project, 2004-2014

    Energy Technology Data Exchange (ETDEWEB)

    LaFreniere, Lorraine M. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-11-01

    This document reviews the performance of the groundwater (and wetlands) restoration program implemented by the Commodity Credit Corporation of the U.S. Department of Agriculture (CCC/USDA) at the former CCC/USDA grain storage facility in Utica, Nebraska, during the first ten years of this initiative (2004-2014). The results of the program for the first five-year period of operation were previously discussed in detail (Argonne 2011). The present report focuses on treatment system operational data and regulatory compliance monitoring results for the site during the second five-year period of operation (2010-2014), together with the results of (1) ongoing monitoring and (2) targeted groundwater sampling for volatile organic compounds (VOCs) analyses conducted at Utica in 2015 (following completion of the tenth year of systems operation), to assess the 10-year progress of the Utica remediation effort.

  7. Disaster exposure as a risk factor for mental health problems, eighteen months, four and ten years post-disaster – a longitudinal study

    Directory of Open Access Journals (Sweden)

    van den Berg Bellis

    2012-09-01

    Full Text Available Abstract Background Disaster experiences have been associated with higher prevalence rates of (mental health problems. The objective of this study was to examine the independent relation between a series of single disaster experiences versus the independent predictive value of a accumulation of disaster experiences, i.e. a sum score of experiences and symptoms of distress and post-traumatic stress disorder (PTSD. Methods Survivors of a fireworks disaster participated in a longitudinal study and completed a questionnaire three weeks (wave 1, eighteen months (wave 2 and four years post-disaster (wave 3. Ten years post-disaster (wave 4 the respondents consisted of native Dutch survivors only. Main outcome measures were general distress and symptoms of PTSD. Results Degree of disaster exposure (sum score and some disaster-related experiences (such as house destroyed, injured, confusion were related to distress at waves 2 and 3. This relation was mediated by distress at an earlier point in time. None of the individual disaster-related experiences was independently related to symptoms of distress. The association between the degree of disaster exposure and symptoms of PTSD at waves 2 and 3 was still statistically significant after controlling for symptoms of distress and PTSD at earlier point in time. The variable ‘house destroyed’ was the only factor that was independently related to symptoms of PTSD at wave 2. Ten years after the disaster, disaster exposure was mediated by symptoms of PTSD at waves 2 and 3. Disaster exposure was not independently related to symptoms of PTSD ten years post-disaster. Conclusions Until 4 years after the disaster, degree of exposure (a sum score was a risk factor for PTSD symptoms while none of the individual disaster experiences could be identified as an independent risk factor. Ten years post-disaster, disaster exposure was no longer an independent risk factor for symptoms of PTSD. Since symptoms of PTSD and

  8. Disaster exposure as a risk factor for mental health problems, eighteen months, four and ten years post-disaster – a longitudinal study

    Science.gov (United States)

    2012-01-01

    Background Disaster experiences have been associated with higher prevalence rates of (mental) health problems. The objective of this study was to examine the independent relation between a series of single disaster experiences versus the independent predictive value of a accumulation of disaster experiences, i.e. a sum score of experiences and symptoms of distress and post-traumatic stress disorder (PTSD). Methods Survivors of a fireworks disaster participated in a longitudinal study and completed a questionnaire three weeks (wave 1), eighteen months (wave 2) and four years post-disaster (wave 3). Ten years post-disaster (wave 4) the respondents consisted of native Dutch survivors only. Main outcome measures were general distress and symptoms of PTSD. Results Degree of disaster exposure (sum score) and some disaster-related experiences (such as house destroyed, injured, confusion) were related to distress at waves 2 and 3. This relation was mediated by distress at an earlier point in time. None of the individual disaster-related experiences was independently related to symptoms of distress. The association between the degree of disaster exposure and symptoms of PTSD at waves 2 and 3 was still statistically significant after controlling for symptoms of distress and PTSD at earlier point in time. The variable ‘house destroyed’ was the only factor that was independently related to symptoms of PTSD at wave 2. Ten years after the disaster, disaster exposure was mediated by symptoms of PTSD at waves 2 and 3. Disaster exposure was not independently related to symptoms of PTSD ten years post-disaster. Conclusions Until 4 years after the disaster, degree of exposure (a sum score) was a risk factor for PTSD symptoms while none of the individual disaster experiences could be identified as an independent risk factor. Ten years post-disaster, disaster exposure was no longer an independent risk factor for symptoms of PTSD. Since symptoms of PTSD and distress at earlier waves

  9. Transfer Effects in Spelling from Transparent Greek to Opaque English in Seven-to-Ten-Year-Old Children

    Science.gov (United States)

    Niolaki, Georgia Z.; Masterson, Jackie

    2012-01-01

    The study investigated single-word spelling performance of 33 English- and 38 Greek-speaking monolingual children, and 46 English- and Greek-speaking bilingual children (age range from 6;7 to 10;1 years). The bilingual children were divided into two groups on the basis of their single-word reading and spelling performance in Greek. In line with…

  10. Ten Years of "Latin-American Journal of Astronomy Education" RELEA: Achievements and Challenges for International Astronomy Education Development

    Science.gov (United States)

    Bretones, Paulo S.; Jafelice, Luiz C.; Horvath, Jorge E.

    2016-01-01

    This study reviews 10 years of "Latin-American Journal of Astronomy Education" (RELEA), showing that the journal has become a valuable resource for publishing and highlights its pathway as scholarly journal. Furthermore, it is also a call to astronomy education specialists to consolidate their efforts considering similar journals…

  11. Ten-Year Trends in Bullying and Related Attitudes Among 4th- to 12th-Graders.

    Science.gov (United States)

    Waasdorp, Tracy Evian; Pas, Elise T; Zablotsky, Benjamin; Bradshaw, Catherine P

    2017-06-01

    Bullying is a significant public health concern, and it has received considerable attention from the media and policymakers over the past decade, which has led some to believe that it is increasing. However, there are limited surveillance data on bullying to inform our understanding of such trends over the course of multiple years. The current study examined the prevalence of bullying and related behaviors between 2005 and 2014 and explored whether any such changes varied across schools or as a function of school-level covariates. Youth self-reports of 13 indicators of bullying and related behaviors were collected from 246 306 students in 109 Maryland schools across 10 years. The data were weighted to reflect the school populations and were analyzed by using longitudinal hierarchical linear modeling to examine changes over time. The covariate-adjusted models indicated a significant improvement over bullying and related concerns in 10 out of 13 indicators (including a decrease in bullying and victimization) for in-person forms (ie, physical, verbal, relational) and cyberbullying. Results also showed an increase in the perceptions that adults do enough to stop bullying and students' feelings of safety and belonging at school. Prevalence of bullying and related behaviors generally decreased over this 10-year period with the most recent years showing the greatest improvements in school climate and reductions in bullying. Additional research is needed to identify factors that contributed to this declining trend. Copyright © 2017 by the American Academy of Pediatrics.

  12. A ten-year analysis of the traumatic maxillofacial and brain injury patient in Amsterdam: Incidence and aetiology

    NARCIS (Netherlands)

    Salentijn, E.G.; Peerdeman, S.M.; Boffano, P.; van den Bergh, B.; Forouzanfar, T.

    2014-01-01

    In the literature it is questioned if the presence of maxillofacial trauma is associated with the presence of brain injury. The aim of this study is to present a 10-year retrospective study of the incidence and aetiology of maxillofacial trauma associated with brain injury that required both oral

  13. A ten-year analysis of the traumatic maxillofacial and brain injury patient in Amsterdam: incidence and aetiology

    NARCIS (Netherlands)

    Salentijn, E.G.; Peerdeman, S.M.; Boffano, P.; van den Bergh, B.; Forouzanfar, T.

    2014-01-01

    In the literature it is questioned if the presence of maxillofacial trauma is associated with the presence of brain injury. The aim of this study is to present a 10-year retrospective study of the incidence and aetiology of maxillofacial trauma associated with brain injury that required both oral

  14. Ten-Year Follow-up of a Blind Patient Chronically Implanted with Epiretinal Prosthesis Argus I.

    Science.gov (United States)

    Yue, Lan; Falabella, Paulo; Christopher, Punita; Wuyyuru, Varalakshmi; Dorn, Jessy; Schor, Paulo; Greenberg, Robert J; Weiland, James D; Humayun, Mark S

    2015-12-01

    The Argus I implant is the first-generation epiretinal prosthesis approved for an investigational clinical trial by the United States Food and Drug Administration. Herein we report testing results obtained from a 10-year follow-up to study the physiologic effects of the bioelectronic visual implant after prolonged chronic electrical stimulation. Case report. One man, 55 years of age when enrolled in the study, underwent surgical implantation of the Argus I in June 2004, followed by periodic tests from July 2004 through June 2014, spanning a total of 10 years. The decade-long follow-up consisted of implant system performance tests, subject visual function evaluation, and implant-retina interface analysis. Changes in electrode impedance and perceptual threshold over the time course; subject's performance on visual function task, orientation, and mobility tests; and optical coherence tomography data, fundus imaging, and fluorescein angiography results for the assessment of subject's implant-retina physical interface. Electrically elicited phosphenes were present 10 years after implantation of an epiretinal stimulator. The test subject not only was able to perceive phosphenes, but also could perform visual tasks at rates well above chance. This decade-long follow-up report provides further support for the use of retinal prostheses as a long-lasting treatment for some types of blindness. Copyright © 2015 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  15. Acacia saligna’s soil legacy effects persist up to ten years after clearing: Implications for ecological restoration

    Czech Academy of Sciences Publication Activity Database

    Nsikani, M. M.; Novoa, Ana; van Wilgen, B. W.; Keet, J.-H.; Gaertner, M.

    2017-01-01

    Roč. 42, č. 8 (2017), s. 880-889 ISSN 1442-9985 R&D Projects: GA ČR GB14-36079G Institutional support: RVO:67985939 Keywords : ecological impact * enzyme activities * invader control * restoration Subject RIV: EH - Ecology, Behaviour OBOR OECD: Ecology Impact factor: 1.708, year: 2016

  16. Long-Term Effects of Otitis Media a Ten-Year Cohort Study of Alaskan Eskimo Children

    Science.gov (United States)

    Kaplan, Gary J.; And Others

    1973-01-01

    Histories of ear disease, otoscopic examinations, and audiologic, intelligence, and achievement tests were obtained from a cohort of 489 Alaskan Eskimo children, followed through the first 10 years of life, to determine whether otitis media (middle ear inflammation) deleteriously affected intellectual functioning and achievement in school.…

  17. Interpersonal Victimization, Posttraumatic Stress Disorder, and Change in Adolescent Substance Use Prevalence over a Ten-Year Period

    Science.gov (United States)

    McCart, Michael R.; Zajac, Kristyn; Danielson, Carla Kmett; Strachan, Martha; Ruggiero, Kenneth J.; Smith, Daniel W.; Saunders, Benjamin E.; Kilpatrick, Dean G.

    2011-01-01

    Epidemiological studies have identified recent declines in specific types of adolescent substance use. The current study examined whether these declines varied among youth with and without a history of interpersonal victimization or posttraumatic stress disorder (PTSD). Data for this study come from two distinct samples of youth (12-17 years of…

  18. A Ten-Year Assessment of a Biomedical Engineering Summer Research Internship within a Comprehensive Cancer Center

    Science.gov (United States)

    Wright, A. S.; Wu, X.; Frye, C. A.; Mathur, A. B.; Patrick, C. W., Jr.

    2007-01-01

    A Biomedical Engineering Internship Program conducted within a Comprehensive Cancer Center over a 10 year period was assessed and evaluated. Although this is a non-traditional location for an internship, it is an ideal site for a multidisciplinary training program for science, technology, engineering, and mathematics (STEM) students. We made a…

  19. Survivorship of medial opening wedge high tibial osteotomy in the elderly: two to ten years of follow up.

    Science.gov (United States)

    Ruangsomboon, Pakpoom; Chareancholvanich, Keerati; Harnroongroj, Thos; Pornrattanamaneewong, Chaturong

    2017-10-01

    Medial opening wedge high tibial osteotomy (MOWHTO) is a well-accepted procedure, which has been widely used for pain relief and varus deformity correction in the osteoarthritic (OA) knee, especially in the young patient. However, in the elderly patient, the efficacy of this procedure is still unknown. Therefore, this study aims to evaluate the survivorship of MOWHTO in elderly patients as the primary outcome. The secondary outcome is to evaluate the loss of correction angle that is the common complication after MOWTHO. A retrospective study of 50 elderly patients (≥ 60 years) was conducted to track survivorship of MOWHTO. All patients were diagnosed with varus OA knee and underwent MOWHTO at our institute. The patients who had previous knee surgery or incomplete data were excluded. Medical records and radiographs of eligible patients were reviewed for recruiting the data. Survivorship of MOWHTO was analyzed using Kaplan-Meier curves. The starting point was the time of operation and the end point was the time of subsequent TKA. The loss of correction angle was defined as the change of medial proximal tibial angle (MPTA) between three months and one year post-operatively. The mean age of patients was 66 ± 5.0 years. The majority of patients were female (74%). The mean correction angle was 10.6 ± 3.6 degrees. The union rate of osteotomy site was 100%. In survival analysis, the median follow-up time was 6.0 ± 3.0 years. Two patients required subsequent conversions to TKA. The survivorship of MOWHTO at four years was 95.5% (95%CI, 96.0 to 98.0). For radiographic assessment, the loss of correction angle was 1.0 ± 0.5 degrees at one year post-operatively. This study proved that MOWHTO in patient ≥60 years had good mid-term survivorship with acceptable complications. This procedure can be the alternative option for the treatment of varus OA knee in the elderly.

  20. Ten year outcomes of participants in the REACT (Randomised Evaluation of Assertive Community Treatment in North London) study.

    Science.gov (United States)

    Killaspy, Helen; Mas-Expósito, Laia; Marston, Louise; King, Michael

    2014-10-24

    A previous randomised controlled trial that investigated Assertive Community Treatment (ACT) in the UK (the REACT Study) found no clinical advantage over usual care delivered by Community Mental Health Teams (CMHTs) at 18 and 36 month follow-ups. No studies have investigated long term clinical and social outcomes for patients receiving ACT. We investigated inpatient service use, social outcomes, service contact and adverse events for the 251 REACT study participants 10 years after randomisation through case note review. Data were analysed using regression models adjusted for original treatment group allocation and changes in treatment group. We found no statistically significant differences in outcomes by original treatment group over the 10 years. Those whose care remained with ACT, or transferred to ACT or forensic services, had more inpatient days over the 10 years (coefficient 223, 95% CI 83 to 363, p = 0.002) than those whose care remained with the CMHTs or were discharged to primary care. Being subject to a Community Treatment Order was associated with a greater chance of being under ACT at 10 year follow-up (OR 6.39, 95% CI 2.98 to 13.70, p teams in this study showed no clinical advantage over usual care provided by CMHTs at 10 year follow-up. We also found that the ACT teams accrued patients from the original study sample who had more complex needs than those who remained with or transferred to the CMHTs or primary care during this period. Further well conducted trials are needed to identify the most cost-effective approaches to supporting successful community living and optimum long term outcomes for this group.

  1. Ten-year chemical evolution of leachate and municipal solid waste incineration bottom ash used in a test road site.

    Science.gov (United States)

    Dabo, David; Badreddine, Rabia; De Windt, Laurent; Drouadaine, Ivan

    2009-12-30

    The use of municipal solid waste incineration (MSWI) bottom ash for road and car-park construction is an appropriate solution to reduce their disposal and the consumption of natural materials. In addition to leaching tests, the environmental impact assessment of such a waste recycling scenario critically needs for reliable long-term field data. This paper addresses a 10-year pilot site where MSWI bottom ashes have been used as road aggregates in Northern France (oceanic temperate climate). The paper focuses on the long-term evolution of leachate chemistry and the mineralogical transformations of MSWI bottom ash over 10 years. Data interpretation is supported by geochemical modeling in terms of main pH-buffering processes. The leachate pH and concentrations in major elements (Ca, Na and Cl) as well as in Al and heavy metals (Cu, Pb and Zn) quickly drop during the first 2 years to asymptotically reach a set of minimum values over 10 years; similar to those of a reference road built with natural calcareous aggregates. SO(4) release makes exception with a slightly increasing trend over time. Carbonation induced by CO(2) inputs, which leads to the successive dissolution of portlandite, CSH and ettringite, is one of the main phenomenon responsible for the geochemical evolution of leachate. On the other hand, mineralogical observations and batch tests demonstrate a relative stability of the MSWI bottom ash inside the subbase layer. In particular, carbonation may be far to be completed and still in progress after 10 years. This is consistent with preferential rainwater flow and dilution at the road edges combined to diffusion inside the subbase layer.

  2. Recovery Potential of a Western Lowland Gorilla Population following a Major Ebola Outbreak: Results from a Ten Year Study

    Science.gov (United States)

    Gatti, Sylvain; Levréro, Florence; Bigot, Elodie; Caillaud, Damien; Pierre, Jean-Sébastien; Ménard, Nelly

    2012-01-01

    Investigating the recovery capacity of wildlife populations following demographic crashes is of great interest to ecologists and conservationists. Opportunities to study these aspects are rare due to the difficulty of monitoring populations both before and after a demographic crash. Ebola outbreaks in central Africa have killed up to 95% of the individuals in affected western lowland gorilla (Gorilla gorilla gorilla) populations. Assessing whether and how fast affected populations recover is essential for the conservation of this critically endangered taxon. The gorilla population visiting Lokoué forest clearing, Odzala-Kokoua National Park, Republic of the Congo, has been monitored before, two years after and six years after Ebola affected it in 2004. This allowed us to describe Ebola's short-term and long-term impacts on the structure of the population. The size of the population, which included around 380 gorillas before the Ebola outbreak, dropped to less than 40 individuals after the outbreak. It then remained stable for six years after the outbreak. However, the demographic structure of this small population has significantly changed. Although several solitary males have disappeared, the immigration of adult females, the formation of new breeding groups, and several birth events suggest that the population is showing potential to recover. During the outbreak, surviving adult and subadult females joined old solitary silverbacks. Those females were subsequently observed joining young silverbacks, forming new breeding groups where they later gave birth. Interestingly, some females were observed joining silverbacks that were unlikely to have sired their infant, but no infanticide was observed. The consequences of the Ebola outbreak on the population structure were different two years and six years after the outbreak. Therefore, our results could be used as demographic indicators to detect and date outbreaks that have happened in other, non-monitored gorilla

  3. Surgical Results of Unruptured Intracranial Aneurysms in the Elderly : Single Center Experience in the Past Ten Years

    Science.gov (United States)

    Jung, Young Jin; Park, Eun Suk; Kwon, Do Hoon; Kwun, Byung Duk; Kim, Chang Jin

    2011-01-01

    Objective As medical advances have increased life expectancy, it has become imperative to develop specific treatment strategies for intracranial aneurysms in the elderly. We therefore analyzed the clinical characteristics and outcomes of the treatment of unruptured intracranial aneurysms in patients older than 70 years. Methods We retrospectively reviewed the medical records and results of neuroimaging modalities on 54 aneurysms of 48 consecutive patients with unruptured intracranial aneurysms. (mean±SD age, 72.11±1.96 years; range, 70-78 years) who underwent surgical clipping over 10 years (May 1999 to June 2010). Results Of the 54 aneurysms, 22 were located in the internal carotid artery, 19 in the middle cerebral artery, 12 in the anterior cerebral artery, and 1 in the superior cerebellar artery. Six patients had multiple aneurysms. Aneurysm size ranged from 3 mm to 17 mm (mean±SD, 6.82±3.07 mm). Fifty of the 54 aneurysms (92.6%) were completely clipped. Three-month outcomes were excellent in 50 (92.6%) aneurysms and good and poor in 2 each (3.7%), with 1 death (2.0%). Procedure-related complications occurred in 7 aneurysms (13.0%), with 2 (3.7%) resulting in permanent neurological deficits, including death. No postoperative subarachnoid hemorrhage occurred during follow-up. The cumulative rates of stroke- or death-free survival at 5 and 10 years were 100% and 78%, respectively. Conclusion Surgical clipping of unruptured intracranial aneurysms in elderly group could get it as a favorable outcome in well selected cases. PMID:21887389

  4. Ten-year follow-up of early intensive self-management guidance in newly diagnosed patients with asthma.

    Science.gov (United States)

    Kauppinen, Ritva Sirkka; Vilkka, Vesa; Hedman, Jouni; Sintonen, Harri

    2011-11-01

    We assessed the 10-year effectiveness of self-management guidance in a prospective follow-up study of patients with asthma when inhaled corticosteroids were used from the beginning in the treatment. Consecutive newly diagnosed asthmatics (n = 162) were randomized: 80 to an intervention group (IG) and 82 to a control group (CG). Lung function (LF), airway hyperresponsiveness (AHR), and health-related quality of life (HRQoL) were examined at 10 years. The advantages of intensive education with regards to LF measured by forced expiratory volume in 1 second and forced vital capacity were seen only after the first year. Later, there were no statistically significant differences in any parameters between the groups. However, during 10-year follow-up, peak expiratory flow, AHR, and HRQoL improved significantly in both groups (no differences as regards gender, smoking, or atopy). At 10 years, 68% of the IG and 75% of the CG patients still showed AHR after histamine challenge. Generic HRQoL scores in both groups equaled that of the age-standardized group a general population but only 50% in the IG and 55% in the CG had normal disease-specific HRQoL scores. According to Global Initiative for Asthma (GINA) criteria 23% of patients in the IG and 25% in the CG had asthma under control. The effectiveness of intensive self-management education could be shown only in the short term. The groups did not differ significantly in any of the parameters investigated, and showed nearly normal LF and HRQoL. AHR improved only partly and only a minority of the patients had asthma under good control according to GINA criteria. This study showed that evaluation of asthma using LF alone does not show the whole truth about asthma treatment results. HRQoL should be used in conjunction with GINA criteria, to assess asthma treatment outcomes. The value and importance of AHR for the evaluation of treatment remains obscure.

  5. Ten-year estimated risk of bone fracture in women with differentiated thyroid cancer under TSH-suppressive levothyroxine therapy.

    Science.gov (United States)

    Vera, Lara; Gay, Stefano; Campomenosi, Claudia; Paolino, Sabrina; Pera, Giorgia; Monti, Eleonora; Mortara, Lorenzo; Seriolo, Bruno; Giusti, Massimo

    2016-01-01

    After thyroidectomy and radioiodine therapy, patients with differentiated thyroid cancer (DTC) are indefinitely treated with levothyroxine (L-T4). Osteoporosis is a debated consequence of hypothyroxinaemia. The aim of this study was to evaluate bone mineral density (BMD) and fracture risk assessed by FRAX in a cohort of DTC women. Seventy-four women with DTC (aged 56.5 ± 9.9 years) treated at the mean age of 51.9 ± 12.0 years were studied. Baseline BMD and FRAX were evaluated after 3.0 years (median). BMD and FRAX were further evaluated 5.5 years (median) after the baseline evaluation. A cohort of 120 euthyroid women, matched for age, BMI, and menopausal status, were evaluated as controls. L-T4 dosages were 813.6 ± 208.8 μg/week and 782.1 ± 184.4 μg/week at the baseline and second evaluation, respectively. The risks of major osteoporotic fracture (MOF) and hip fracture (HF) were similar in DTC patients and in controls. In DTC women, significant changes in FRAX were found, with a higher increase in the probability of HF than of MOF. A similar change was found in controls. A significant inverse correlation (P < 0.001) between L-T4 dosage and HF/MOF probability on both first and second evaluations was found. A significant inverse correlation (P = 0.05) was found between fT4, TSH and duration of therapy and HF/MOF probability only on the second evaluation. FRAX increase is a multi-factorial, age-related phenomenon. The absence of correlations between L-T4 dosage, length of therapy or fT4 levels and FRAX does not enable us to attribute an increased fracture risk to DTC women with well-controlled disease on therapy. (Endokrynol Pol 2016; 67 (4): 350-358).

  6. Soil-transmitted helminth infections among plantation sector schoolchildren in Sri Lanka: prevalence after ten years of preventive chemotherapy.

    Directory of Open Access Journals (Sweden)

    Kithsiri Gunawardena

    2011-09-01

    Full Text Available BACKGROUND: The plantation sector in Sri Lanka lags behind the rest of the country in terms of living conditions and health. In 1992, a sector-wide survey of children aged 3-12 years and women of reproductive age showed >90% prevalence of soil-transmitted helminth infections. Biannual mass de-worming targeting children aged 3-18 years started in 1994 and was continued until 2005. The present study was carried out to assess the status of infection four years after cessation of mass de-worming. METHODS/FINDINGS: A school-based cross-sectional survey was carried out. Faecal samples from approximately 20 children from each of 114 schools in five districts were examined using the modified Kato-Katz technique. Data regarding the school, the child's family and household sanitation were recorded after inspection of schools and households. Multivariate analysis was carried out using logistic regression, to identify risk factors for infection. Faecal samples were obtained from 1890 children. In 4/5 districts, >20% were infected with one or more helminth species. Overall combined prevalence was 29.0%; 11.6% had infections of moderate-heavy intensity. The commonest infection was Ascaris lumbricoides, present in all five districts, as was Trichuris trichiura. Hookworm was not detected in two districts. Multivariate analysis identified low altitude and maternal under-education as risk factors for all three infections. Poor household sanitation was identified as a risk factor for A. lumbricoides and hookworm, but not T. trichiura infections. CONCLUSIONS/SIGNIFICANCE: The results indicate that regular mass de-worming of plantation sector children should be resumed along with more emphasis on better sanitation and health education. They show that even after 10 years of mass chemotherapy, prevalence can bounce back after cessation of preventive chemotherapy, if the initial force of transmission is strong and other long-term control measures are not concomitantly

  7. Germline mutation in BRCA1 or BRCA2 and ten-year survival for women diagnosed with epithelial ovarian cancer.

    Science.gov (United States)

    Candido-dos-Reis, Francisco J; Song, Honglin; Goode, Ellen L; Cunningham, Julie M; Fridley, Brooke L; Larson, Melissa C; Alsop, Kathryn; Dicks, Ed; Harrington, Patricia; Ramus, Susan J; de Fazio, Anna; Mitchell, Gillian; Fereday, Sian; Bolton, Kelly L; Gourley, Charlie; Michie, Caroline; Karlan, Beth; Lester, Jenny; Walsh, Christine; Cass, Ilana; Olsson, Håkan; Gore, Martin; Benitez, Javier J; Garcia, Maria J; Andrulis, Irene; Mulligan, Anna Marie; Glendon, Gord; Blanco, Ignacio; Lazaro, Conxi; Whittemore, Alice S; McGuire, Valerie; Sieh, Weiva; Montagna, Marco; Alducci, Elisa; Sadetzki, Siegal; Chetrit, Angela; Kwong, Ava; Kjaer, Susanne K; Jensen, Allan; Høgdall, Estrid; Neuhausen, Susan; Nussbaum, Robert; Daly, Mary; Greene, Mark H; Mai, Phuong L; Loud, Jennifer T; Moysich, Kirsten; Toland, Amanda E; Lambrechts, Diether; Ellis, Steve; Frost, Debra; Brenton, James D; Tischkowitz, Marc; Easton, Douglas F; Antoniou, Antonis; Chenevix-Trench, Georgia; Gayther, Simon A; Bowtell, David; Pharoah, Paul D P

    2015-02-01

    To analyze the effect of germline mutations in BRCA1 and BRCA2 on mortality in patients with ovarian cancer up to 10 years after diagnosis. We used unpublished survival time data for 2,242 patients from two case-control studies and extended survival time data for 4,314 patients from previously reported studies. All participants had been screened for deleterious germline mutations in BRCA1 and BRCA2. Survival time was analyzed for the combined data using Cox proportional hazard models with BRCA1 and BRCA2 as time-varying covariates. Competing risks were analyzed using Fine and Gray model. The combined 10-year overall survival rate was 30% [95% confidence interval (CI), 28%-31%] for non-carriers, 25% (95% CI, 22%-28%) for BRCA1 carriers, and 35% (95% CI, 30%-41%) for BRCA2 carriers. The HR for BRCA1 was 0.53 at time zero and increased over time becoming greater than one at 4.8 years. For BRCA2, the HR was 0.42 at time zero and increased over time (predicted to become greater than 1 at 10.5 years). The results were similar when restricted to 3,202 patients with high-grade serous tumors and to ovarian cancer-specific mortality. BRCA1/2 mutations are associated with better short-term survival, but this advantage decreases over time and in BRCA1 carriers is eventually reversed. This may have important implications for therapy of both primary and relapsed disease and for analysis of long-term survival in clinical trials of new agents, particularly those that are effective in BRCA1/2 mutation carriers. ©2014 American Association for Cancer Research.

  8. Baseline characteristics and effects of ten years of growth hormone (GH) replacement therapy in adults previously treated with pituitary irradiation.

    Science.gov (United States)

    Elbornsson, Mariam; Götherström, Galina; Bengtsson, Bengt-Åke; Johannsson, Gudmundur; Svensson, Johan

    2013-12-01

    Little is known of the importance of previous irradiation therapy for baseline characteristics and responsiveness to GH replacement in GH deficient (GHD) adults. In this prospective, single-centre, open-label study, the effects of 10-year GH replacement were determined in 18 GHD adults that had previously received conventional external fractionated pituitary irradiation therapy (IRR group) and 18 non-irradiated GHD patients (non-IRR group). All patients had adult onset disease and complete deficiency of anterior pituitary hormones and both groups were comparable in terms of age, gender, body mass index (BMI), and waist:hip ratio. At baseline, IRR patients had higher serum triglyceride (TG) and insulin levels and lower high density lipoprotein (HDL)-cholesterol (HDL-C) level than non-IRR patients (all pGH replacement improved body composition, bone mass and serum lipid profile without any between-group differences, except for a marginally more beneficial response in serum TG level in the IRR patients. After 10 years, there was no between-group difference in any variable after correction for a higher replacement dose of glucocorticoids in the IRR patients at study end using an analysis of covariance. During the 10-year GH replacement, 5 IRR patients suffered from vascular events (2 fatal) whereas only one non-fatal vascular event occurred in the non-IRR patients. IRR patients with GHD display a more severely impaired cardiovascular risk profile at baseline, which was reversed by the 10-year GH replacement after correction for the higher glucocorticoid dose at study end. However, vascular events occurred more frequently in the IRR patients. © 2013.

  9. A Ten-Year Study on the Prevalence and Frequency of Risk Factors for Breast Cancer in Sabzevar, Iran

    Directory of Open Access Journals (Sweden)

    Masoumeh Hashemian

    2016-07-01

    Full Text Available Background & aim: Evaluation of prevalence of risk factors for breast cancer in different regions of Iran and identification of their significant effect on this disease can promote the prevention and reduction of breast cancer incidence. Therefore, this study aimed to evaluate the prevalence, demographic characteristics, and frequency of the risk factors of breast cancer during 10 years. Methods:This cross-sectional study was conducted on 160 women with breast cancer during 10 years. The samples, referred by health connectors and registration centers for patients with cancer, were selected using census sampling. Research tool was a reliable and valid researcher-made questionnaire, validity and reliability of which were confirmed. Data analysis was performed in SPSS version 16 using descriptive statistics. Results: In total, mean age of surviving women was 50.7±1.2 years. The highest incidence rate of breast cancer was 35.2% in the group of participants aged 40-49, while the highest prevalence rate of this disease was 0.432 per 1000 samples in a group of patients aged 50- 59 years. Moreover, the most frequent risk factors for this disease were previous use of oral contraceptive pills (OCP (56.8% and positive family history (19%. Conclusion: The results of this study were indicative of positive family history as a certain risk factor for breast cancer in Sabzevar. Therefore, it is recommended that special attention be paid to women with positive family history of breast cancer. Therefore, prioritization of breast cancer screening and prevention programs is of paramount importance in this regard.

  10. Is severe early childhood caries predictive of caries and fluorosis in permanent teeth? Ten-year follow-up

    Directory of Open Access Journals (Sweden)

    Danila Lorena NUNES-DOS-SANTOS

    2017-05-01

    Full Text Available Abstract Introduction Severe early childhood caries is defined as the presence of any sign of decay in children younger than three years. Objective This retrospective longitudinal observational study investigated caries and fluorosis in children with S-ECC from a city with fluoridated water. Material and method We included children under the age of three years who followed a maternal and child dental care program between the years of 1997 and 2003. The children were divided into 2 groups: group 1 (S-ECC and group 2 (no caries. Guardians were contacted by telephone or mail. Caregivers completed questionnaire on socio-demographic and behavioral variables. The clinical dental examinations were performed in a dental clinic to assess caries experience and dental fluorosis. Multiple linear regression was used to determine factors associated with DMFT, and multivariate analysis by multiple logistic regression was used to determine the possible independent factors associated with the occurrence of fluorosis. Result The sample consisted of 126 patients aged 8-12 years, of whom 52.4% were male. The presence of S-ECC increased the DMFT by an average of 0.84 (p = 0.02. Both the frequency of tooth brushing and the use of standard toothpaste were protective factors from the development of caries in the permanent dentition (p <0.05. Parents who reported that their children refused to brush their teeth had 70% less chance of developing fluorosis (p = 0.02. Conclusion The presence of S-ECC was a risk factor for the development of caries in the permanent dentition, but not for the development of fluorosis.

  11. Germline mutation in BRCA1 or BRCA2 and ten-year survival for women diagnosed with epithelial ovarian cancer

    DEFF Research Database (Denmark)

    Candido-dos-Reis, Francisco J; Song, Honglin; Goode, Ellen L

    2015-01-01

    ,314 patients from previously reported studies. All participants had been screened for deleterious germline mutations in BRCA1 and BRCA2. Survival time was analyzed for the combined data using Cox proportional hazard models with BRCA1 and BRCA2 as time-varying covariates. Competing risks were analyzed using...... greater than one at 4.8 years. For BRCA2, the HR was 0.42 at time zero and increased over time (predicted to become greater than 1 at 10.5 years). The results were similar when restricted to 3,202 patients with high-grade serous tumors and to ovarian cancer-specific mortality. CONCLUSIONS: BRCA1......PURPOSE: To analyze the effect of germline mutations in BRCA1 and BRCA2 on mortality in patients with ovarian cancer up to 10 years after diagnosis. EXPERIMENTAL DESIGN: We used unpublished survival time data for 2,242 patients from two case-control studies and extended survival time data for 4...

  12. [Evaluation of France's contributions to the Global Fund to Fight AIDS, Tuberculosis and Malaria: Ten years later].

    Science.gov (United States)

    Kerouedan, D

    2014-01-01

    For 30 years, France has been very committed politically in the international combat against AIDS. The discovery of the AIDS virus at the Pasteur Institute in 1983, the AIDS summit meeting convened by Simone Veil in 1994, the excellence of research by French institutions on its virologic and other aspects as well as the socioeconomic and anthropological issues, and the strong commitment to international technical cooperation against this disease - all these have made (and continue to make) France a major political, technical, and financial participant in this battle against the combined pandemic of AIDS and tuberculosis. More than 10 years after the creation of the Global Fund, 5 years after the first evaluation of this Fund, and 2 years before the schedule for meeting the Millennium Development Goals, an assessment commissioned in 2013 from a French consulting firm of the French contributions is timely. The study was expected. Its results are disappointing. Why? Because the team chosen to conduct the assessment has a limited knowledge of the history of the interventions already funded by France and of the results of earlier assessments. The point was not to repeat the same observations but to move forward to see where they lead. In addition, the current and coming challenges are not considered. The countries to which France is providing cooperation are on the continent that after 30 years remains the most heavily affected by the pandemic. Several transitions are occurring there simultaneously: epidemiologic, demographic and urban. These metamorphoses influencing social values quite substantially, as well as risk factors for transmission of the AIDS virus; at the same time, they facilitate overcrowding and the propagation of tuberculosis. Nor do the authors consider the resistance of these infectious agents to the most commonly used drugs. The effects of the propagation of AIDS, of the expansion of armed conflicts in French-speaking Africa and of the sexual

  13. Adjuvant radiotherapy for pathologic stage T3/4 adenocarcinoma of the prostate: Ten-year update

    International Nuclear Information System (INIS)

    Anscher, Mitchell S.; Robertson, Cary N.; Prosnitz, Leonard R.

    1995-01-01

    Purpose: To determine the role of adjuvant postoperative radiotherapy (RT) following radical prostatectomy (RP) in a group of patients with pathologic Stage T3/4 adenocarcinoma of the prostate followed for a median of 10 years after treatment. Methods and Materials: Between 1970 and 1983, 159 patients underwent RP for newly diagnosed adenocarcinoma of the prostate and were found to have pathologic Stage T3/4 tumors. Forty-six received adjuvant RT and 113 did not. Radiotherapy usually consisted of 45-50 Gy to the whole pelvis followed by a boost to the prostate bed of 10-15 Gy, to a total dose of 55-65 Gy. Patients were analyzed with respect to survival, disease-free survival, local control, and freedom from distant metastases. A rising prostate-specific antigen in the absence of other evidence of relapse was scored as a separate category of recurrence. Results: Both groups of patients have been followed for a median of 10 years. The actuarial survival at 10 and 15 years was 62% and 62% for the RT group compared to 52% and 37%, respectively, for the RP group (p = 0.18). The disease-free survival for the RT group was 55% and 48% at 10 and 15 years, respectively, compared to 37% and 33% for the RP group (p = 0.16). Similarly, there was no difference in the rate of distant metastases between the two groups. In contrast, the local relapse rate was significantly reduced by the addition of postoperative radiotherapy. The actuarial local control rate at 10 and 15 years was 92% and 82%, respectively, for the RT group vs. 60% and 53% for the RP group (p 0.002). Conclusions: While postoperative pelvic RT significantly improves local control compared to RP alone for pathologic Stage T3/4 prostate cancer, it has no impact on distant metastases and consequently does not improve survival. These data are consistent with the conclusion that many patients with pathologic Stage T3/4 prostate cancer have occult metastases at presentation and will not be cured by local therapies alone

  14. Ten-Year Locoregional Recurrence Risks in Women With Nodal Micrometastatic Breast Cancer Staged With Axillary Dissection

    Energy Technology Data Exchange (ETDEWEB)

    Lupe, Krystine [Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver Island Centre, Victoria, BC (Canada); Truong, Pauline T., E-mail: ptruong@bccancer.bc.ca [Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver Island Centre, Victoria, BC (Canada); Breast Cancer Outcomes Unit, British Columbia Cancer Agency, Vancouver Island Centre, Victoria, BC (Canada); University of British Columbia, Victoria, BC (Canada); Alexander, Cheryl; Speers, Caroline [Breast Cancer Outcomes Unit, British Columbia Cancer Agency, Vancouver Island Centre, Victoria, BC (Canada); Tyldesley, Scott [Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver Island Centre, Victoria, BC (Canada); Breast Cancer Outcomes Unit, British Columbia Cancer Agency, Vancouver Island Centre, Victoria, BC (Canada); University of British Columbia, Victoria, BC (Canada)

    2011-12-01

    Purpose: To compare the locoregional recurrence (LRR) rates in patients with nodal mirometastases (pNmic) with those in patients with node-negative (pN0) and macroscopic node-positive (pNmac) breast cancer; and to evaluate the LRR rates according to locoregional treatment of pNmic disease. Methods and Materials: The subjects were 9,616 women diagnosed between 1989 and 1999 with Stage pT1-T2, pN0, pNmic, or pNmac, M0 breast cancer. All women had undergone axillary dissection. The Kaplan-Meier local recurrence, regional recurrence, and LRR rates were compared among those with pN0 (n = 7,977), pNmic (n = 490) and pNmac (n = 1,149) and according to locoregional treatment. Multivariate analysis was performed to identify the significant factors associated with LRR. Results: The median follow-up was 11 years. The 10-year Kaplan-Meier recurrence rate in the pN0, pNmic, and pNmac cohorts was 6.1%, 6.8%, and 8.7% for local recurrence; 3.1%, 6.2%, and 10.3% for regional recurrence; and 8.0%, 11.6%, and 15.2% for LRR, respectively (all p < .001). In the pNmic patients, the 10-year regional recurrence rate was 6.4% with breast-conserving surgery plus breast radiotherapy (RT), 5.4% with breast-conserving surgery plus locoregional RT, 4.6% with mastectomy alone, 11.1% with mastectomy plus chest wall RT, and 10.7% with mastectomy plus locoregional RT. In patients with pNmic disease and age <45 years, Grade 3 histologic features, lymphovascular invasion, nodal ratio >0.25, and estrogen receptor-negative disease, the 10-year LRR rates were 15-20%. On multivariate analysis of the entire cohort, pNmic was associated with greater LRR than Stage pN0 (hazard ratio [HR], 1.6; p = .002). On multivariate analysis of pNmic patients only, age <45 years was associated with significantly greater LRR (HR, 1.9; p = .03), and trends for greater LRR were observed with a nodal ratio >0.25 (HR, 2.0; p = .07) and lymphovascular invasion (HR, 1.7; p = .07). Conclusion: Women with pNmic had a greater

  15. Ten-year survival and patient-reported outcomes of a medial unicompartmental knee arthroplasty incorporating an all-polyethylene tibial component.

    Science.gov (United States)

    Scott, Chloe E H; Wade, Frazer A; MacDonald, Deborah; Nutton, Richard W

    2018-05-01

    Biomechanical studies have suggested that proximal tibial strain is elevated in UKAs incorporating all-polyethylene tibial components with concern that this leads to premature failure. This study reports minimum 10-year outcomes for a UKA incorporating an all-polyethylene tibial component to determine whether these concerns were realised. 109 fixed bearing UKAs (97 patients, mean age 68 (range 48-87), 54/97 (56%) female) with all-polyethylene tibial components were followed up for ≥ 10 years with Oxford Knee Scores, Forgotten Joint Scores and Kaplan-Meier analysis. 106/109 implants were 7 mm, 3 were 9.5 mm. Ten-year survival was 85.5% (78.6-92.4 95% CI) with the end-point failure for any reason. Unexplained pain was the commonest mode of failure (6/17) followed by lateral compartment osteoarthritis (5/17) and tibial subsidence/loosening (4/17). Revision rate was highest at 2-5 years due to revisions for unexplained pain. Ten-year survival was worse in patients  30 (p = 0.017) and in those with postoperative increases in medial tibial sclerosis (p  30 was 2.9 (1.2-6.9 95% CI). In those with intact UKAs at 10 years, mean Oxford Knee Score was 34.8 ± 10.7, Forgotten Joint Score was 37.9 ± 26.7 and 96% were satisfied with their knee. The high rate of early failure between 2 and 5 years in this all-polyethylene tibial component UKA did not persist in the long term. Though medial proximal tibial metabolic changes appear to persist they are not necessarily symptomatic. BMI > 30 and age < 65 years were significant risk factors for revision.

  16. Total hip arthroplasty for patients with Crowe type IV developmental dysplasia of the hip: Ten years results.

    Science.gov (United States)

    Zeng, Wei-Nan; Liu, Jun-Li; Wang, Fu-You; Zhang, Xin; Fan, Hua-Quan; Chen, Guang-Xing; Guo, Lin; Duan, Xiao-Jun; Zhou, Qiang; Yang, Liu

    2017-06-01

    The aim of this study was to determine the rate of union, functional results and complications in patients with Crowe IV developmental dysplasia of the hip (DDH) who underwent cementless total hip arthroplasty (THA) with S-ROM prostheses and subtrochanteric transverse shortening osteotomy. Forty-five patients (52 hips) operated between January 2005 and May 2008, with a mean age of 40.6 years at surgery were followed. The mean follow-up period was 9.8 years. Clinical outcomes, radiographic outcomes and complications were evaluated. Osteotomy union occurred in 52 of 52 femurs (100%). Mean Harris hip score improved from 33.7 ± 4.7 preoperatively to 81.2 ± 6.3, 90.8 ± 5.3 and 89.8 ± 7.1 at 1, 5 and 10 years postoperatively. Two patients had temporary sciatic nerve paralysis postoperatively, and 2 patients experienced early postoperative dislocation. Two patients complained about mild longer limb length than the non-operated limb at the last follow-up. Three hips showed osteolysis in Gruen zone 1, and 1 hip showed osteolysis in zone 1 and 7. No implants were revised, and no signs of component loosening and migration were observed at the last follow-up visit. S-ROM stem combined with transverse subtrochanteric shortening osteotomy in THA for patients with Crowe type IV DDH has good clinical results with small risk of complications. Copyright © 2017. Published by Elsevier Ltd.

  17. Peptic ulcer disease risk in chronic kidney disease: ten-year incidence, ulcer location, and ulcerogenic effect of medications.

    Science.gov (United States)

    Liang, Chih-Chia; Muo, Chih-Hsin; Wang, I-Kuan; Chang, Chiz-Tzung; Chou, Che-Yi; Liu, Jiung-Hsiun; Yen, Tzung-Hai; Huang, Chiu-Ching; Chung, Chi-Jung

    2014-01-01

    We aimed at determining peptic ulcer disease (PUD) incidence among chronic kidney disease (CKD) patients during 1998-2008, compared to patients without CKD, and at examining associations between CKD and PUD. Data for 1998-2008 were extracted from the National Health Insurance Research Database in Taiwan. The annual PUD incidence (cases per thousand persons per year) was calculated separately for patients with and without CKD. Characteristics of patients with newly diagnosed PUD (n = 16322) were compared to those of a control group without PUD (n = 32644). The 2 groups were matched for age, sex, and index year. Odds ratios (OR) and 95% confidence intervals (CI) were estimated by logistic regression. Over the 10-year period, the PUD incidence was ∼10-12 times higher in CKD patients than in those without CKD. Its incidence in elderly CKD patients increased rapidly over time. For CKD patients, most PUD events (>95%) were managed during hospitalization. Peptic ulcer risk, adjusted for all potential confounders, was much higher in CKD patients undergoing hemodialysis (adjusted OR, 9.74; 95% CI, 7.11-13.31). Maintenance hemodialysis patients were 2 times more likely to have gastric ulcers than duodenal ulcers, while CKD patients not on dialysis had similar risks for both. There were no significant interactions between medications and CKD status on the peptic ulcer risk. Unlike CKD patients on nonsteroidal anti-inflammatory drugs and clopidogrel, those on aspirin did not have a higher peptic ulcer risk (adjusted OR, 0.88; 95% CI, 0.44-1.77). CKD patients have a substantially increased PUD risk, and the majority of CKD patients with PUD require hospital management. Further, peptic ulcer risk is affected by hemodialysis therapy, patient status (inpatient vs. outpatient), and ulcerogenic medications.

  18. Physical self-esteem--a ten-year follow-up study from early adolescence to early adulthood.

    Science.gov (United States)

    Raustorp, Anders; Lindwall, Magnus

    2015-02-01

    One variable that has been consistently associated with adolescents' physical activity is perceived activity competence. Perceived physical (or sport) competence is considered a sub-domain to the physical self-esteem or self-worth (i.e., a person's valuation of what is good and worthy in their self-description). This study aimed to describe levels of and inter-correlations among physical self-esteem, physical activity, and body mass index in a longitudinal design spanning adolescence to early adulthood. At mean ages of 12.7, 15.7, 17.7 and 22.7 years, we measured perceived physical self-esteem in 39 (22 boys) Swedish adolescents. Physical activity (steps/day) for four consecutive schooldays, height, and weight were also measured. No significant difference between the four time points for any variable of perceived physical self-esteem was seen, neither in boys nor girls. In general, all physical self-variables revealed non-linear trajectories across time, where the general trend was an increase during the younger ages followed by a decrease during older ages. At ages 12 and 15 years in boys and girls physical condition and physical strength as well as body attractiveness and physical strength, respectively, had the strongest correlations to physical self-esteem. At age 17 and 22 years sports competence had the strongest correlation to self-esteem in girls, while body attractiveness and physical strength had the strongest correlation to self-esteem in boys. An overall stability in physical self-esteem was found. However the impact of a sub-domain upon physical self-esteem vary during adolescence and early adulthood. Such information may be useful when creating physical activity programs that support and develop physical self-esteem.

  19. Ten years maintaining MACAO-VLTI units in operation in the Very Large Telescope at Paranal Observatory

    Science.gov (United States)

    Salgado, F.; Hudepohl, G.

    2016-07-01

    More than 10 years have already passed since the first Multiple Application Curvature Adaptive Optics (MACAO) facilities got the first light in UT2 the 18th of April, 2003, in the Very Large Telescope (VLT) at Paranal Observatory. The achievable image sharpness of a ground-based telescope is normally limited by the effect of atmospheric turbulence. However, with Adaptive Optics (AO) techniques, this major drawback can be overcome so that the telescope produces images that are as sharp as theoretically possible, i.e., as if they were taken from space. [1] The intention of this document is summarize in few pages some highlights related with the activities needed to keep MACAO units in operation. Some statistics of problems based in Action Remedy tool is included, showing how through these years the number of problems has been reduced, even when there are still some unsolved ones. Some lessons have been learned and there are others one to learn. Corrective and predictive maintenance performed are shown too like the current measurements, transfer functions measurements, thermography pictures, health checks measuring interaction matrix and flat vectors to detect dead APDs or short circuits in the DM, etc. Some forced interventions are included as well like the removal of the cabinets from Coude rooms to avoid that acoustic noise and vibrations perturb the operations, the deformable mirrors reached by cooling leaks and a mirror that got rusty are shown too. Well knowledge of the system, good interaction between different disciplines groups to perform corrective and preventive maintenance seems to be key aspects of keeping it under control and operative during all these years leading to this good result.

  20. Ten-Year Follow-up on Tumor Growth and Hearing in Patients Observed With an Intracanalicular Vestibular Schwannoma

    DEFF Research Database (Denmark)

    Kirchmann, Malene; Karnov, Kirstine; Hansen, Søren

    2017-01-01

    . Serviceable hearing was preserved in 34% according to AAO-HNS (class A-B) and in 58% according to the word recognition score (class I-II). Rate of hearing loss was higher in patients with growing tumors.  CONCLUSION: Tumor growth occurred in only a minority of patients diagnosed with an intracanalicular VS...... during 10 years of observation. The risk of hearing loss is small in patients with normal discrimination at diagnosis. Serviceable hearing is preserved spontaneously in 34% according to AAO-HNS and in 58% according to the word recognition score. ...