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Sample records for tnavots elmo somelar

  1. Integrin-linked kinase interactions with ELMO2 modulate cell polarity.

    Science.gov (United States)

    Ho, Ernest; Irvine, Tames; Vilk, Gregory J A; Lajoie, Gilles; Ravichandran, Kodi S; D'Souza, Sudhir J A; Dagnino, Lina

    2009-07-01

    Cell polarization is a key prerequisite for directed migration during development, tissue regeneration, and metastasis. Integrin-linked kinase (ILK) is a scaffold protein essential for cell polarization, but very little is known about the precise mechanisms whereby ILK modulates polarization in normal epithelia. Elucidating these mechanisms is essential to understand tissue morphogenesis, transformation, and repair. Here we identify a novel ILK protein complex that includes Engulfment and Cell Motility 2 (ELMO2). We also demonstrate the presence of RhoG in ILK-ELMO2 complexes, and the localization of this multiprotein species specifically to the leading lamellipodia of polarized cells. Significantly, the ability of RhoG to bind ELMO is crucial for ILK induction of cell polarization, and the joint expression of ILK and ELMO2 synergistically promotes the induction of front-rear polarity and haptotactic migration. This places RhoG-ELMO2-ILK complexes in a key position for the development of cell polarity and forward movement. Although ILK is a component of many diverse multiprotein species that may contribute to cell polarization, expression of dominant-negative ELMO2 mutants is sufficient to abolish the ability of ILK to promote cell polarization. Thus, its interaction with ELMO2 and RhoG is essential for the ability of ILK to induce front-rear cell polarity.

  2. Nash sovremennik Tammsaare / Elmo Nüganen ; interv. Nikolai Hrustaljov

    Index Scriptorium Estoniae

    Nüganen, Elmo, 1962-

    2006-01-01

    Tallinna Linnateatris 12. märtsil esietendunud Elmo Nüganeni Tammsaare-lavastusest, mis põhineb "Tõe ja õiguse" neljandal osal. Dramatiseeringu on teinud Elmo Nüganen, peaosades Indrek Sammul ja Hele Kõre

  3. Neuronal adaptor FE65 stimulates Rac1-mediated neurite outgrowth by recruiting and activating ELMO1.

    Science.gov (United States)

    Li, Wen; Tam, Ka Ming Vincent; Chan, Wai Wan Ray; Koon, Alex Chun; Ngo, Jacky Chi Ki; Chan, Ho Yin Edwin; Lau, Kwok-Fai

    2018-04-03

    Neurite outgrowth is a crucial process in developing neurons for neural network formation. Understanding the regulatory mechanisms of neurite outgrowth is essential for developing strategies to stimulate neurite regeneration after nerve injury and in neurodegenerative disorders. FE65 is a brain-enriched adaptor that stimulates Rac1-mediated neurite elongation. However, the precise mechanism by which FE65 promotes the process remains elusive. Here, we show that ELMO1, a subunit of ELMO1-DOCK180 bipartite Rac1 GEF, interacts with the FE65 N-terminal region. Overexpression of FE65 and/or ELMO1 enhances whereas knockdown of FE65 or ELMO1 inhibits neurite outgrowth and Rac1 activation. The effect of FE65 alone or together with ELMO1 is attenuated by an FE65 double mutation that disrupts FE65-ELMO1 interaction. Notably, FE65 is found to activate ELMO1 by diminishing ELMO1 intramolecular autoinhibitory interaction and to promote the targeting of ELMO1 to the plasma membrane where Rac1 is activated. We also show that FE65, ELMO1 and DOCK180 form a tripartite complex. Knockdown of DOCK180 reduces the stimulatory effect of FE65-ELMO1 on Rac1 activation and neurite outgrowth. Thus, we identify a novel mechanism that FE65 stimulates Rac1-mediated neurite outgrowth by recruiting and activating of ELMO1. Published under license by The American Society for Biochemistry and Molecular Biology, Inc.

  4. Magnetics calculations for an ELMO Bumpy square

    International Nuclear Information System (INIS)

    Santoro, R.T.; Uckan, N.A.; Schmidt, R.J.

    1985-01-01

    Advanced ELMO Bumpy Torus (EBT) concepts have been studied in an effort to determine the potential for new and different concepts as confinement experiments or as reactors. Several magnetic configurations based on the EBT confinement concept were developed including the ELMO Bumpy Square (EBS). The EBS was selected as a possible candidate for near-term study because of its potential for resolving critical EBT issues, for its desirability as a reactor, and for anticipated contributions to the physics and technology of fusion. This paper summarizes magnetics calculations that were carried out in support of studies to assess the merits of an EBS

  5. Elmo bumpy square plasma confinement device

    Science.gov (United States)

    Owen, L.W.

    1985-01-01

    The invention is an Elmo bumpy type plasma confinement device having a polygonal configuration of closed magnet field lines for improved plasma confinement. In the preferred embodiment, the device is of a square configuration which is referred to as an Elmo bumpy square (EBS). The EBS is formed by four linear magnetic mirror sections each comprising a plurality of axisymmetric assemblies connected in series and linked by 90/sup 0/ sections of a high magnetic field toroidal solenoid type field generating coils. These coils provide corner confinement with a minimum of radial dispersion of the confined plasma to minimize the detrimental effects of the toroidal curvature of the magnetic field. Each corner is formed by a plurality of circular or elliptical coils aligned about the corner radius to provide maximum continuity in the closing of the magnetic field lines about the square configuration confining the plasma within a vacuum vessel located within the various coils forming the square configuration confinement geometry.

  6. ELMO Bumpy Square proposal

    International Nuclear Information System (INIS)

    Dory, R.A.; Uckan, N.A.; Ard, W.B.

    1986-10-01

    The ELMO Bumpy Square (EBS) concept consists of four straight magnetic mirror arrays linked by four high-field corner coils. Extensive calculations show that this configuration offers major improvements over the ELMO Bumpy Torus (EBT) in particle confinement, heating, transport, ring production, and stability. The components of the EBT device at Oak Ridge National Laboratory can be reconfigured into a square arrangement having straight sides composed of EBT coils, with new microwave cavities and high-field corners designed and built for this application. The elimination of neoclassical convection, identified as the dominant mechanism for the limited confinement in EBT, will give the EBS device substantially improved confinement and the flexibility to explore the concepts that produce this improvement. The primary goals of the EBS program are twofold: first, to improve the physics of confinement in toroidal systems by developing the concepts of plasma stabilization using the effects of energetic electrons and confinement optimization using magnetic field shaping and electrostatic potential control to limit particle drift, and second, to develop bumpy toroid devices as attractive candidates for fusion reactors. This report presents a brief review of the physics analyses that support the EBS concept, discussions of the design and expected performance of the EBS device, a description of the EBS experimental program, and a review of the reactor potential of bumpy toroid configurations. Detailed information is presented in the appendices

  7. ELMO Bumpy Torus

    International Nuclear Information System (INIS)

    Berry, L.A.; Hedrick, C.L.; Uckan, N.A.

    1979-03-01

    The ELMO Bumpy Torus (EBT) program of experiment, theory, and reactor studies has been a remarkably successful one. In the five years since EBT-I began operating, work has progressed from a demonstration of macrostability to an increasingly detailed understanding of transport properties. Collisionless scaling (tau/sub E/ increases with temperature) has been observed, and the magnitude of the energy confinement time is consistent with neoclassical theory. Experiments on EBT-S (for scale) are now being conducted at the increased magnetic field levels and higher microwave power and frequency made possible by a 28-GHz gyrotron development program. A review of the program is given

  8. Integrin-linked kinase and ELMO2 modulate recycling endosomes in keratinocytes.

    Science.gov (United States)

    Ho, Ernest; Ivanova, Iordanka A; Dagnino, Lina

    2016-12-01

    The formation of tight cell-cell junctions is essential in the epidermis for its barrier properties. In this tissue, keratinocytes follow a differentiation program tightly associated with their movement from the innermost basal to the outer suprabasal layers, and with changes in their cell-cell adhesion profile. Intercellular adhesion in keratinocytes is mediated through cell-cell contacts, including E-cadherin-based adherens junctions. Although the mechanisms that mediate E-cadherin delivery to the plasma membrane have been widely studied in simple epithelia, this process is less well understood in the stratified epidermis. In this study, we have investigated the role of Engulfment and Cell Motility 2 (ELMO2) and integrin-linked kinase (ILK) in the positioning of E-cadherin-containing recycling endosomes during establishment of cell-cell contacts in differentiating keratinocytes. We now show that induction of keratinocyte differentiation by Ca 2+ is accompanied by localization of ELMO2 and ILK to Rab4- and Rab11a-containing recycling endosomes. The positioning of long-loop Rab11a-positive endosomes at areas adjacent to cell-cell contacts is disrupted in ELMO2- or ILK-deficient keratinocytes, and is associated with impaired localization of E-cadherin to cell borders. Our studies show a previously unrecognized role for ELMO2 and ILK in modulation of endosomal positioning, which may play key roles in epidermal sheet maintenance and permeability barrier function. Copyright © 2016 Elsevier B.V. All rights reserved.

  9. Elmo Bumpy Torus Reactor

    International Nuclear Information System (INIS)

    McAlees, D.G.; Uckan, N.A.; Lidsky, L.M.

    1976-01-01

    In the Elmo Bumpy Torus Reactor (EBTR) study the feasibility of achieving a fusion power plant based on the EBT confinement concept was evaluated. If the present understanding of the physics can be extrapolated to reactor scale devices the reactor could operate at high beta, high power density, and at steady state. The high aspect ratio of the device eases the accessibility, structural design and remote maintenance problems which are common to low aspect ratio machines. A version of the EBTR reference design described here could be constructed with only minor extrapolations in available technology

  10. ELMO Bumpy Torus fusion-reactor design study

    International Nuclear Information System (INIS)

    Bathke, C.G.; Krakowski, R.A.

    1981-01-01

    A complete power plant design of a 1200-MWe ELMO Bumpy Torus Reactor (EBTR) is described that emphasizes those features that are unique to the EBT confinement concept, with subsystems and balance-of-plant items that are generic to magnetic fusion being adopted from past, more extensive tokamak reactor designs

  11. An ELMO2-RhoG-ILK network modulates microtubule dynamics.

    Science.gov (United States)

    Jackson, Bradley C; Ivanova, Iordanka A; Dagnino, Lina

    2015-07-15

    ELMO2 belongs to a family of scaffold proteins involved in phagocytosis and cell motility. ELMO2 can simultaneously bind integrin-linked kinase (ILK) and RhoG, forming tripartite ERI complexes. These complexes are involved in promoting β1 integrin-dependent directional migration in undifferentiated epidermal keratinocytes. ELMO2 and ILK have also separately been implicated in microtubule regulation at integrin-containing focal adhesions. During differentiation, epidermal keratinocytes cease to express integrins, but ERI complexes persist. Here we show an integrin-independent role of ERI complexes in modulation of microtubule dynamics in differentiated keratinocytes. Depletion of ERI complexes by inactivating the Ilk gene in these cells reduces microtubule growth and increases the frequency of catastrophe. Reciprocally, exogenous expression of ELMO2 or RhoG stabilizes microtubules, but only if ILK is also present. Mechanistically, activation of Rac1 downstream from ERI complexes mediates their effects on microtubule stability. In this pathway, Rac1 serves as a hub to modulate microtubule dynamics through two different routes: 1) phosphorylation and inactivation of the microtubule-destabilizing protein stathmin and 2) phosphorylation and inactivation of GSK-3β, which leads to the activation of CRMP2, promoting microtubule growth. At the cellular level, the absence of ERI species impairs Ca(2+)-mediated formation of adherens junctions, critical to maintaining mechanical integrity in the epidermis. Our findings support a key role for ERI species in integrin-independent stabilization of the microtubule network in differentiated keratinocytes. © 2015 Jackson et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  12. Emerging role of ILK and ELMO2 in the integration of adhesion and migration pathways.

    Science.gov (United States)

    Ho, Ernest; Dagnino, Lina

    2012-01-01

    Integrins and their associated proteins are essential components of the cellular machinery that modulates adhesion and migration. In particular, integrin-linked kinase (ILK), which binds to the cytoplasmic tail of β1 integrins, is required for migration in a variety of cell types. We previously identified engulfment and motility 2 (ELMO2) as an ILK-binding protein in epidermal keratinocytes. Recently, we investigated the biological role of the ILK/ELMO2 complexes, and found that they exist in the cytoplasm. ILK/ELMO2 species are recruited by active RhoG to the plasma membrane, where they induce Rac1 activation and formation of lamellipodia at the leading edge of migrating cells. A large number of growth factors and cytokines induce keratinocyte migration. However, we found that formation of RhoG/ELMO2/ILK complexes occurs selectively upon stimulation by epidermal growth factor, but not by transforming growth factor-β1 or keratinocyte growth factor. Herein we discuss the relevance of these complexes to our understanding of the molecular mechanisms involved in cell migration, as well as their potential functions in morphogenesis and tissue regeneration following injury.

  13. Knock-down of ELMO1 in Paediatric Rhabdomyosarcoma Cells by Nanoparticle Mediated siRNA Delivery

    Directory of Open Access Journals (Sweden)

    Xinyue Huang

    2016-03-01

    Full Text Available Rhabdomyosarcoma (RMS is the most common soft tissue sarcoma that is found in children and has a poor outcome for those with metastatic disease. Two histological groups have been distinguished - embryonal (ERMS and alveolar (ARMS forms. The ARMS subtype has higher rates of metastasis, as well as higher levels of ELMO1, which is thought to be involved in cell migration. Therefore, the knock-down of ELMO1 by targeted siRNA could provide a mechanism to prevent the metastatic behaviour of ARMS cells. However, challenges still lie in the delivery of nucleotides to a tumour site. Herein, we have described the use of a variety of mesoporous silica nanoparticles as a delivery system for siRNA that is specific for ELMO1 and shown the effective reduction in cell invasive behaviour in these cells.

  14. ELMO Bumpy Torus

    International Nuclear Information System (INIS)

    1978-01-01

    The ELMO Bumpy Torus (EBT) program of experiment, theory, and reactor studies has been a remarkably successful one. In the five years since EBT-I began operating, work has progressed from demonstrating macrostability to an increasingly detailed understanding of transport properties. Collisionless scaling (tau/sub E/ increases with temperature) has been observed and the magnitude of the energy confinement time is consistent with neoclassical theory. Experiments on EBT-S are now being conducted at the increased magnetic field levels and higher microwave power and frequency made possible by a 28-GHz gyrotron development program. Initial results confirm our assumptions of neoclassical scaling. In conjunction with the experimental advances, EBT theory now has a well-developed transport theory which models the physics which we now think to be important: for example, it yields negative ambipolar electric fields which are consistent with those measured. Stability calculations continue to predict stable equilibrium with β/sub ring/ approx. β/sub core/ approx. 20 to 40%

  15. The ELMO Bumpy Torus: present and future

    International Nuclear Information System (INIS)

    Uckan, N.A.

    1978-01-01

    The ELMO Bumpy Torus (EBT) experiment at ORNL was designed to circumvent the MHD stability problem encountered in standard bumpy tori by using the ''minimum-B'' properties of annular high-beta, hot-electron plasmas formed by microwave heating. The EBT combines the attractive features of both mirrors and tokamaks. The feasibility of this combined system has been demonstrated successfully in the EBT-I experiment and discussed at greater length elsewhere. The present status of the EBT research activities at ORNL is described briefly

  16. Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock.

    Science.gov (United States)

    Hernández-Vásquez, Magda Nohemí; Adame-García, Sendi Rafael; Hamoud, Noumeira; Chidiac, Rony; Reyes-Cruz, Guadalupe; Gratton, Jean Philippe; Côté, Jean-François; Vázquez-Prado, José

    2017-07-21

    Developmental angiogenesis and the maintenance of the blood-brain barrier involve endothelial cell adhesion, which is linked to cytoskeletal dynamics. GPR124 (also known as TEM5/ADGRA2) is an adhesion G protein-coupled receptor family member that plays a pivotal role in brain angiogenesis and in ensuring a tight blood-brain barrier. However, the signaling properties of GPR124 remain poorly defined. Here, we show that ectopic expression of GPR124 promotes cell adhesion, additive to extracellular matrix-dependent effect, coupled with filopodia and lamellipodia formation and an enrichment of a pool of the G protein-coupled receptor at actin-rich cellular protrusions containing VASP, a filopodial marker. Accordingly, GPR124-expressing cells also displayed increased activation of both Rac and Cdc42 GTPases. Mechanistically, we uncover novel direct interactions between endogenous GPR124 and the Rho guanine nucleotide exchange factors Elmo/Dock and intersectin (ITSN). Small fragments of either Elmo or ITSN1 that bind GPR124 blocked GPR124-induced cell adhesion. In addition, Gβγ interacts with the C-terminal tail of GPR124 and promotes the formation of a GPR124-Elmo complex. Furthermore, GPR124 also promotes the activation of the Elmo-Dock complex, as measured by Elmo phosphorylation on a conserved C-terminal tyrosine residue. Interestingly, Elmo and ITSN1 also interact with each other independently of their GPR124-recognition regions. Moreover, endogenous phospho-Elmo and ITSN1 co-localize with GPR124 at lamellipodia of adhering endothelial cells, where GPR124 expression contributes to polarity acquisition during wound healing. Collectively, our results indicate that GPR124 promotes cell adhesion via Elmo-Dock and ITSN. This constitutes a previously unrecognized complex formed of atypical and conventional Rho guanine nucleotide exchange factors for Rac and Cdc42 that is putatively involved in GPR124-dependent angiogenic responses. © 2017 by The American Society for

  17. Heating of energetic electrons and ELMO ring formation in symmetric mirror facility

    International Nuclear Information System (INIS)

    Quon, B.H.; Dandl, R.A.; Lazar, N.H.; Wuerker, R.F.

    1982-01-01

    The spatial structure of the high beta, hot-electron ECH plasma, (ELMO Ring), has been studied by using a Hall probe array diagnostic system which measures the diamagnetic field of the hot electron plasma in a large number of spatial locations. The steady state pressure profile obtained using a two-gaussian geometric model that best fits the measurements is found to peak at the mirror midplane near the vacuum field second harmonic resonant point. The radial width of the ring is typically 4 to 7 cm, and the axial length extends significantly beyond the second harmonic resonance zone of the total magnetic field. The radial thickness and the Ring beta are increased by multiple frequency ECH. The electron ring is observed to evolve from a sloshing-like turning point distribution which was observed in the early times following a microwave turnon, demonstrating stochastic processes involved in ELMO Ring formation

  18. The Jurassic section along McElmo Canyon in southwestern Colorado

    Science.gov (United States)

    O'Sullivan, Robert B.

    1997-01-01

    In McElmo Canyon, Jurassic rocks are 1500-1600 ft thick. Lower Jurassic rocks of the Glen Canyon Group include (in ascending order) Wingate Sandstone, Kayenta Formation and Navajo Sandstone. Middle Jurassic rocks are represented by the San Rafael Group, which includes the Entrada Sandstone and overlying Wanakah Formation. Upper Jurassic rocks comprise the Junction Creek Sandstone overlain by the Morrison Formation. The Burro Canyon Formation, generally considered to be Lower Cretaceous, may be Late Jurassic in the McElmo Canyon area and is discussed with the Jurassic. The Upper Triassic Chinle Formation in the subsurface underlies, and the Upper Cretaceous Dakota Sandstone overlies, the Jurassic section. An unconformity is present at the base of the Glen Canyon Group (J-0), at the base of the San Rafael Group (J-2), and at the base of the Junction Creek Sandstone (J-5). Another unconformity of Cretaceous age is at the base of the Dakota Sandstone. Most of the Jurassic rocks consist of fluviatile, lacustrine and eolian deposits. The basal part of the Entrada Sandstone and the Wanakah Formation may be of marginal marine origin.

  19. Developing an Effective Intervention for Incarcerated Teen Fathers: The Baby Elmo Program

    Science.gov (United States)

    Brito, Natalie; Barr, Rachel; Rodriguez, Jennifer; Shauffer, Carole

    2012-01-01

    The absence of a father figure has been linked to very poor developmental outcomes. The Baby Elmo Program, a parenting and structured visitation program, aims to form and maintain bonds between children and their incarcerated teen fathers. The program is taught and supervised by probation staff in juvenile detention facilities. This intervention…

  20. Involvement of Tiam1, RhoG and ELMO2/ILK in Rac1-mediated phagocytosis in human trabecular meshwork cells.

    Science.gov (United States)

    Peotter, Jennifer L; Phillips, Jenny; Tong, Tiegang; Dimeo, Kaylee; Gonzalez, Jose M; Peters, Donna M

    2016-10-01

    We previously demonstrated that an αvβ5 integrin/FAK- mediated pathway regulated the phagocytic properties of human trabecular meshwork (HTM) cells. Here we demonstrate that this process is mediated by Rac-1 and a previously unreported signaling pathway that utilizes the Tiam1 as well as a novel ILK/RhoG/ELMO2 signaling pathway. Phagocytosis in both a TM-1 cell line and normal HTM cells was mediated by Rac1 and could be significantly decreased by >75% using the Rac1 inhibitor EHop-016. Knockdown of Rac1 in TM-1 cells also inhibited phagocytosis by 40% whereas overexpression of a constitutively active Rac1 or stimulation with PDGF increased phagocytosis by 83% and 32% respectively. Tiam1 was involved in regulating phagocytosis. Knockdown of Tiam1 inhibited phagocytosis by 72% while overexpression of Tiam1 C1199 increased phagocytosis by 75%. Other upstream effectors of Rac1 found to be involved included ELMO2, RhoG, and ILK. Knockdowns of ELMO2, ILK, and RhoG caused a reduction in phagocytosis by 51%, 55% and 46% respectively. In contrast, knockdown of Vav2 and Dock1 or overexpression of Vav2 Y159/172F did not cause a significant change in phagocytosis. These data suggest a novel link between Tiam1 and RhoG/ILK /ELMO2 pathway as upstream effectors of the Rac1-mediated phagocytic process in TM cells. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. A program to develop advanced EBT [ELMO Bumpy Torus] concepts and international collaboration on the Bumpy Torus concept: Final report

    International Nuclear Information System (INIS)

    1987-01-01

    This project was undertaken to develop innovative concepts for improving the performance of ELMO Bumpy Torus devices in those aspects of plasma confinement that are particularly relevant to an eventual EBT reactor concept. These include effective magnetic utilization using Andreoletti coils, enhanced confinement using positive ambipolar potentials, and attractive divertor concepts that are compatible with formation and maintenance of ELMO rings. Each of the three major objectives was achieved and, except for the divertor studies, documented for publication and presentation at major scientific meetings. This report provides a brief recapitulation of the major results achieved in the form of a collection of those publications, together with this Introduction

  2. Monte Carlo neutral density calculations for ELMO Bumpy Torus

    International Nuclear Information System (INIS)

    Davis, W.A.; Colchin, R.J.

    1986-11-01

    The steady-state nature of the ELMO Bumpy Torus (EBT) plasma implies that the neutral density at any point inside the plasma volume will determine the local particle confinement time. This paper describes a Monte Carlo calculation of three-dimensional atomic and molecular neutral density profiles in EBT. The calculation has been done using various models for neutral source points, for launching schemes, for plasma profiles, and for plasma densities and temperatures. Calculated results are compared with experimental observations - principally spectroscopic measurements - both for guidance in normalization and for overall consistency checks. Implications of the predicted neutral profiles for the fast-ion-decay measurement of neutral densities are also addressed

  3. Electron energy confinement in ELMO Bumpy Torus (EBT)

    International Nuclear Information System (INIS)

    Hiroe, S.; Haste, G.R.; Dandl, R.A.

    1979-06-01

    Using a calibrated, solid-state, soft x-ray detector, the electron temperature and density have been measured over a wide range of operating conditions of ELMO Bumpy Torus (EBT). The empirical relations of the temperature or the density to the microwave power and the ambient pressure have been determined. The toroidally stored energy has been observed to increase as the stored energy of the hot electron annulus increases. The energy confinement time has been obtained for various plasma parameters and has been found to agree with the neoclassical theory. The advantages of EBT collisionless scaling for fusion plasma confinement have been noted, i.e., n/sub e/tau/sub E/ increases as T/sub e/ 1 5 in the collisionless regime

  4. The calcium-sensing receptor changes cell shape via a beta-arrestin-1 ARNO ARF6 ELMO protein network.

    Science.gov (United States)

    Bouschet, Tristan; Martin, Stéphane; Kanamarlapudi, Venkateswarlu; Mundell, Stuart; Henley, Jeremy M

    2007-08-01

    G-protein-coupled receptors (GPCRs) transduce the binding of extracellular stimuli into intracellular signalling cascades that can lead to morphological changes. Here, we demonstrate that stimulation of the calcium-sensing receptor (CaSR), a GPCR that promotes chemotaxis by detecting increases in extracellular calcium, triggers plasma membrane (PM) ruffling via a pathway that involves beta-arrestin 1, Arf nucleotide binding site opener (ARNO), ADP-ribosylating factor 6 (ARF6) and engulfment and cell motility protein (ELMO). Expression of dominant negative beta-arrestin 1 or its knockdown with siRNA impaired the CaSR-induced PM ruffling response. Expression of a catalytically inactive ARNO also reduced CaSR-induced PM ruffling. Furthermore, beta-arrestin 1 co-immunoprecipitated with the CaSR and ARNO under resting conditions. Agonist treatment did not markedly alter beta-arrestin 1 binding to the CaSR or to ARNO but it did elicit the translocation and colocalisation of the CaSR, beta-arrestin 1 and ARNO to membrane protrusions. Furthermore, ARF6 and ELMO, two proteins known to couple ARNO to the cytoskeleton, were required for CaSR-dependent morphological changes and translocated to the PM ruffles. These data suggest that cells ruffle upon CaSR stimulation via a mechanism that involves translocation of beta-arrestin 1 pre-assembled with the CaSR or ARNO, and that ELMO plays an essential role in this CaSR-signalling-induced cytoskeletal reorganisation.

  5. Influence of globalmagnetic perturbations on plasma behavior in Elmo Bumpy Torus

    International Nuclear Information System (INIS)

    Quon, B.H.; Dandl, R.A.; Colestock, P.L.; Bieniosek, F.M.; Ikegami, H.

    1979-02-01

    The sensitivity of plasma confinement to magnetic field error effects has been tested experimentally using externally introduced global field errors on the ELMO Bumpy Torus (EBT). Below a critical error field (deltaB/sub r//B)/sub cr/ of approx. = to 0.6-1 x 10 -3 the plasma was observed to be essentially free from convective cells, toroidal currents, and instabilities. This observed critical value is comparable to a neoclassical critical field error (deltaB/sub r//B)/sub cr/ approx. = rho/R, the ratio of the ion Larmor radius to the major radius of the torus

  6. Numerical model for radial transport in the ELMO Bumpy Torus

    International Nuclear Information System (INIS)

    Jaeger, E.F.; Hedrick, C.L.

    1977-11-01

    Neutral and charged particle densities and temperatures are calculated as functions of radius for the toroidal plasma in the ELMO Bumpy Torus (EBT) experiment. Energy dependent ionization and charge-exchange rates, ambipolar diffusion, and self-consistent radial electric field profiles are included. Variation in magnetic field due to finite plasma pressure, effects of energetic electron rings, and transport due to drift waves and magnetic field errors are neglected. Diffusion is assumed to be neoclassical with enhanced losses at low collisionalities. The model reproduces many of the observed features of EBT operation in the quiescent toroidal (T) mode. The self-consistently calculated electric field is everywhere positive (not as in experiments) unless enhanced electron collisionality is included. Solutions for advanced EBT's are obtained and confinement parameters predicted

  7. Transient waveform acquisition system for the ELMO Bumpy Torus

    International Nuclear Information System (INIS)

    Young, K.G.; Burris, R.D.; Hillis, D.H.; Overbey, D.R.

    1984-10-01

    The transient waveform system described in this report is designed to acquire analog waveforms from the ELMO Bumpy Torus (EBT) diagnostic experiments. Pressure, density, synchrotron radiation, etc., are acquired and digitized with a Kinetic Systems TR812 transient recorder and associated modules located in a CAMAC crate. The system can simultaneously acquire, display, and transmit sets of data consisting of identification parameters and up to 1024 data points for 1 to 64 input signals (frequency range = 0.01 pulse/s to 100 kHz) of data every one or more minutes; thus, it can run continuously without operator intervention. The data are taken on a VAX 11/780 and transmitted to a data base on a DECSystem-10. To aid the programmer in making future modifications to the system, detailed documentation using the Yourdon structural methods has been given

  8. Thomson scattering on ELMO Bumpy Torus

    International Nuclear Information System (INIS)

    Cobble, J.A.

    1985-04-01

    Below 10 12 cm -3 density, a Thomson scattering experiment is an exacting task. Aside from the low signal level, the core plasma in this instance is bathed in high-energy x rays, surrounded by a glowing molecular surface plasma, and heated steady state by microwaves. This means that the noise level from radiation is high and the environment is extremely harsh-so harsh that much effort is required to overcome system damage. In spite of this, the ELMO Bumpy Torus (EBT) system has proven itself capable of providing reliable n/sub e/ and T/sub e/ measurements at densities as low as 2 x 10 11 cm -3 . Radial scans across 20 cm of the plasma diameter have been obtained on a routine basis, and the resulting information has been a great help in understanding confinement in the EBT plasma. The bulk electron properties are revealed as flat profiles of n/sub e/ and T/sub e/, with density ranging from 0.5 to 2.0 x 10 12 cm -3 and temperature decreasing from 100 to 20 eV as pressure in the discharge is increased at constant power. Evidence is presented for a suprathermal tail, which amounts to about 10% of the electron distribution at low pressures. The validity of this conclusion is supported by two independent sensitivity calibrations

  9. ELMO model predicts the price of electric power; ELMO-malli saehkoen hinnan ennustamiseksi

    Energy Technology Data Exchange (ETDEWEB)

    Antila, H. [Electrowatt-Ekono Oy, Helsinki (Finland)

    2001-07-01

    Electrowatt-Ekono has developed a new model, by which it is possible to make long-term prognoses on the development of electricity prices in the Nordic Countries. The ELMO model can be used as an analysis service of the electricity markets and estimation of the profitability of long-term power distribution contracts with different scenarios. It can also be applied for calculation of technical and economical fundamentals for new power plants, and for estimation of the effects of different taxation models on the emissions of power generation. The model describes the whole power generation system, the power and heat consumption and transmission. The Finnish power generation system is based on the Electrowatt-Ekono's boiler database by combining different data elements. Calculation is based on the assumption that the Nordic power generation system is used optimally, and that the production costs are minimised. In practise the effectively operated electricity markets ensure the optimal use of the production system. The market area to be described consists of Finland and Sweden. The spot prices have long been the same. Norway has been treated as a separate market area. The most potential power generation system, the power consumption and the power transmission system are presumed for the target year during a normal rainfall situation. The basic scenario is calculated on the basis of the preconditional data. The calculation is carried out on hourly basis, which enables the estimation of the price variation of electric power between different times during the day and seasons. The system optimises the power generation on the basis of electricity and heat consumption curves and fuel prices. The result is an hourly limit price for electric power. Estimates are presented as standard form reports. Prices are presented as average annuals, in the seasonal base, and in hourly or daily basis for different seasons.

  10. Space potential profiles in ELMO Bumpy Torus (EBT) experiment

    International Nuclear Information System (INIS)

    Bieniosek, F.M.; Connor, K.A.

    1983-01-01

    Spatially resolved measurements of the electric space potential in the ELMO Bumpy Torus (EBT) have been made by a heavy ion beam probe. The EBT-I device is characterized by positive potentials in the surface plasma the order of 100 V and by a nearly symmetric potential well in the core plasma of up to 300 V with respect to the surface potential. The EBT-S device has a similar potential structure with well depth and peak potential similar to or greater than that of EBT-I. Peak potential and well depth increase as the edge gas pressure is lowered and as the microwave power is increased. The potential structure is strongly linked to the specific heating geometry. The ambipolar electric field is large enough generally to dominate the core electron neoclassical diffusion. The potential profile is approximately parabolic in the core, which is shown to be a natural consequence of the spatially uniform plasma source function

  11. Nuclear performance calculations for the ELMO Bumpy Torus Reactor (EBTR) reference design

    International Nuclear Information System (INIS)

    Santoro, R.T.; Barnes, J.M.

    1977-12-01

    The nuclear performance of the ELMO Bumpy Torus Reactor reference design has been calculated using the one-dimensional discrete ordinates code ANISN and the latest available ENDF/B-IV transport cross-section data and nuclear response functions. The calculated results include estimates of the spatial and integral heating rate with emphasis on the recovery of fusion neutron energy in the blanket assembly and minimization of the energy deposition rates in the cryogenic magnet coil assemblies. The tritium breeding ratio in the natural lithium-laden blanket was calculated to be 1.29 tritium nuclei per incident neutron. The radiation damage in the reactor structural material and in the magnet assembly is also given

  12. Kinetic transport model for the ELMO Bumpy Torus

    International Nuclear Information System (INIS)

    Jaeger, E.F.; Hedrick, C.L.; Tolliver, J.S.

    1978-05-01

    A bounce-averaged drift kinetic equation is solved for the toroidal plasma in the ELMO Bumpy Torus (EBT). The distribution function is assumed isotropic in pitch angle and calculated as a function of radius and speed using finite differences on a two-dimensional grid. A Fokker-Planck representation of the collision operator includes Coulomb, microwave, ionizing, and charge-exchange collisions. Ion and electron fluxes, computed as integrals of the distribution function, are of comparable magnitude for ambipolar potentials which are approximately self-consistent. Initial results assume an unperturbed distribution function which is Maxwellian; however, this is not a necessary assumption in the model. Careful accounting of loss regions where electric and magnetic poloidal drifts cancel (super banana particle orbits) leads to ion loss rates which are in some cases two orders of magnitude greater than electron rates. In these cases, radially inward pointing self-consistent electric fields occur with potentials on the order of a few times the ion temperature. These negative field results are in approximate agreement with experiment and appear to be stable to the electric field runaway encountered in positive field cases

  13. ELMO Bumpy Torus Reactor and power plant: conceptual design study

    International Nuclear Information System (INIS)

    Bathke, C.G.; Dudziak, D.J.; Krakowski, R.A.

    1981-08-01

    A complete power plant design of a 1200-MWe ELMO Bumpy Torus Reactor (EBTR) is presented. An emphasis is placed on those features that are unique to the EBT confinement concept, with subsystems and balance-of-plant items that are more generic to magnetic fusion being adapted from past, more extensive tokamak reactor designs. Similar to the latter tokamak studies, this conceptual EBTR design also emphasizes the use of conventional or near state-of-the-art engineering technology and materials. An emphasis is also placed on system accessibility, reliability, and maintainability, as these crucial and desirable characteristics relate to the unique high-aspect-ratio configuration of EBTs. Equal and strong emphasis is given to physics, engineering/technology, and costing/economics components of this design effort. Parametric optimizations and sensitivity studies, using cost-of-electricity as an object function, are reported. Based on these results, the direction for future improvement on an already attractive reactor design is identified

  14. Epidermal growth factor induction of front–rear polarity and migration in keratinocytes is mediated by integrin-linked kinase and ELMO2

    Science.gov (United States)

    Ho, Ernest; Dagnino, Lina

    2012-01-01

    Epidermal growth factor (EGF) is a potent chemotactic and mitogenic factor for epidermal keratinocytes, and these properties are central for normal epidermal regeneration after injury. The involvement of mitogen-activated protein kinases as mediators of the proliferative effects of EGF is well established. However, the molecular mechanisms that mediate motogenic responses to this growth factor are not clearly understood. An obligatory step for forward cell migration is the development of front–rear polarity and formation of lamellipodia at the leading edge. We show that stimulation of epidermal keratinocytes with EGF, but not with other growth factors, induces development of front–rear polarity and directional migration through a pathway that requires integrin-linked kinase (ILK), Engulfment and Cell Motility-2 (ELMO2), integrin β1, and Rac1. Furthermore, EGF induction of front–rear polarity and chemotaxis require the tyrosine kinase activity of the EGF receptor and are mediated by complexes containing active RhoG, ELMO2, and ILK. Our findings reveal a novel link between EGF receptor stimulation, ILK-containing complexes, and activation of small Rho GTPases necessary for acquisition of front–rear polarity and forward movement. PMID:22160594

  15. Epidermal growth factor induction of front-rear polarity and migration in keratinocytes is mediated by integrin-linked kinase and ELMO2.

    Science.gov (United States)

    Ho, Ernest; Dagnino, Lina

    2012-02-01

    Epidermal growth factor (EGF) is a potent chemotactic and mitogenic factor for epidermal keratinocytes, and these properties are central for normal epidermal regeneration after injury. The involvement of mitogen-activated protein kinases as mediators of the proliferative effects of EGF is well established. However, the molecular mechanisms that mediate motogenic responses to this growth factor are not clearly understood. An obligatory step for forward cell migration is the development of front-rear polarity and formation of lamellipodia at the leading edge. We show that stimulation of epidermal keratinocytes with EGF, but not with other growth factors, induces development of front-rear polarity and directional migration through a pathway that requires integrin-linked kinase (ILK), Engulfment and Cell Motility-2 (ELMO2), integrin β1, and Rac1. Furthermore, EGF induction of front-rear polarity and chemotaxis require the tyrosine kinase activity of the EGF receptor and are mediated by complexes containing active RhoG, ELMO2, and ILK. Our findings reveal a novel link between EGF receptor stimulation, ILK-containing complexes, and activation of small Rho GTPases necessary for acquisition of front-rear polarity and forward movement.

  16. Variations in CCR5, but not HFE, ELMO1, or SLC12A3, are associated with susceptibility to kidney disease in north Indian individuals with type 2 diabetes.

    Science.gov (United States)

    Yadav, Ashok K; Kumar, Vinod; Dutta, Pinaki; Bhansali, Anil; Jha, Vivekanand

    2014-11-01

    Diabetic nephropathy (DN), the leading cause of end-stage renal disease worldwide, may have a genetic component. In the present study, we investigated variations in a set of genes with susceptibility to DN in a north Indian population. Four genes (HFE, ELMO1, SLC12A3, and CCR5) were selected on the basis of reported association with type 2 diabetes and nephropathy. In all, 417 diabetic subjects (215 without kidney disease [DM] and 202 with DN) and 197 healthy controls (HC) were evaluated for variations in HFE (845 G>A and 187G>C), SLC12A3 (g.34372G>A), CCR5 (59029A>G), and ELMO1 (+9170 G>A). Polymorphism analysis was performed by polymerase chain reaction-restriction fragment length polymorphism and Taqman allele discrimination assays. Significant differences were found in genotype and allelic frequency in SLC12A3 (g.34372G>A) between diabetic subjects and HC (P A (AA+GA) genotype between diabetic subjects with and without nephropathy. However, the CCR5 59029AA genotype and A allele were significantly more frequent in diabetics compared with the HC (P = 0.01 and 0.03, respectively) and subjects with DN versus DM (P = 0.002 and 0.01, respectively). For ELMO1 (+9170 G>A), the GG genotype frequency was higher in the diabetic versus HC group. There were no differences in the frequency of HFE-845 G>A and HFE-187G>C among the groups. This study shows that the CCR5 AA genotype is over-represented in subjects with kidney disease due to type 2 diabetes. The CCR5 59029G>A and ELMO1 (+9170 G>A) loci are more frequent, and the SLC12A3 34372 AA genotype is associated with a reduced risk of diabetes. © 2014 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and Wiley Publishing Asia Pty Ltd.

  17. [Polymorphism g.37190613 G>A of the ELMO1 gene in the Mexican population: potential marker for clinical-surgical pathology].

    Science.gov (United States)

    Topete-González, Luz Rosalba; Ramirez-Garcia, Sergio Alberto; Charles-Niño, Claudia; Villa-Ruano, Nemesio; Mosso-González, Clemente; Dávalos-Rodríguez, Nory Omayra

    2014-01-01

    ELMO1 is a gene located at locus 7p14.2-14.1 that codifies a regulatory protein involved in fibrogenesis, cell migration, phagocytosis and apoptosis. This gene presents a single nucleotide polymorphism, which appears to be linked with the development of diabetic nephropathy. Currently, there are no studies in regard to the presence of such polymorphism in the Mexican population. Therefore, the aim of this work was to estimate the frequency rate of alleles and genotypes of polymorphism rs1345365 from ELMO1 in Mexican mestizos who inhabit the west and the southeast regions of Mexico in order to generate reliable data for further association studies. There were 322 individuals who were screened for the identification of polymorphism rs1345365 using genomic DNA from leucocytes as a template for PCR-PASA reactions. Amplicons were separated in 7% PAGE and visualized after staining with silver nitrate. The reference allele (A) was the most frequent in both western and southeastern populations of Mexico. In addition, a different genotype distribution was found with respect to other populations. The results of this study indicate that both populations are in Hardy-Weinberg equilibrium. This study also reveals a low frequency rate of the ancestral genotype for the polymorphism rs1345365 in mestizos from the western and southeastern regions of Mexico.

  18. Radial transport in the Elmo Bumpy Torus in collisionless electron regimes

    International Nuclear Information System (INIS)

    Jaeger, E.F.; Hedrick, C.L.; Spong, D.A.

    1979-01-01

    One important area of disagreement between radial transport theory and the ELMO Bumpy Torus (EBT) experiment has been the degree of collisionality of the toroidal plasma electrons. Experiment shows relatively warm electrons (kTsub(e) approximately 300-600eV) and collisionless scaling, i.e. energy confinement increasing with temperature. But results of early one-dimensional (1-D), neoclassical transport models with radially inward pointing electric fields are limited to relatively cool electrons (kTsub(e) approximately 100-200eV) and collisional scaling. In this paper these early results are extended to include lowest-order effects of ion diffusion in regions where poloidal drift frequencies are small. The effects of direct, or non-diffusive, losses in such regions are neglected along with the effects of finite radial electric fields on electron transport coefficients and of self-consistent poloidal electric fields on ion transport coefficients. Results show that solutions in the collisionless electron regime do exist. Furthermore, when the effects of finite electron ring beta on magnetic fields near the plasma edge are included, these solutions occur at power levels consistent with experiment. (author)

  19. Study of plasma confinement in ELMO Bumpy Torus with a heavy-ion beam probe

    Energy Technology Data Exchange (ETDEWEB)

    Bieniosek, F. M.

    1981-01-01

    Plasma confinement in ELMO Bumpy Torus (EBT) is generally strongly dependent on an ambipolar electric field. Spatially resolved measurements of the resulting electric space potential phi/sub sp/ have been made in a single plasma cross section by the heavy-ion beam probe. This diagnostic injects a 4-60-keV beam of (usually) Cs/sup +/ ions into the plasma. Measurement of the energy of Cs/sup 2 +/ secondary ions leaving the plasma gives a continuous monitor of the local space potential. In addition, the total detected Cs/sup 2 +/ ion current is proportional to the product of the local electron density and the ionization rate, which, in turn, is a function of the electron temperature. This signal, nf(T/sub e/), is sensitive to all three electron distributions found in EBT - those of the cold surface plasma, the warm core plasma, and the hot electron ring.

  20. Study of plasma confinement in ELMO Bumpy Torus with a heavy-ion beam probe

    International Nuclear Information System (INIS)

    Bieniosek, F.M.

    1981-01-01

    Plasma confinement in ELMO Bumpy Torus (EBT) is generally strongly dependent on an ambipolar electric field. Spatially resolved measurements of the resulting electric space potential phi/sub sp/ have been made in a single plasma cross section by the heavy-ion beam probe. This diagnostic injects a 4-60-keV beam of (usually) Cs + ions into the plasma. Measurement of the energy of Cs 2+ secondary ions leaving the plasma gives a continuous monitor of the local space potential. In addition, the total detected Cs 2+ ion current is proportional to the product of the local electron density and the ionization rate, which, in turn, is a function of the electron temperature. This signal, nf(T/sub e/), is sensitive to all three electron distributions found in EBT - those of the cold surface plasma, the warm core plasma, and the hot electron ring

  1. Performance analyses of Elmo Bumpy Torus plasmas and plasma support systems

    International Nuclear Information System (INIS)

    Fenstermacher, M.E.

    1979-01-01

    The development and applcation of the OASIS Code (Operational Analysis of ELMO Bumpy Torus Support and Ignition Systems) for the study of EBT device and plasma performance are presented. The code performs a time-independent, zero-dimensional self-consistent calculation of plasma and plasmasupport systems parameters for the physics and engineering of EBT devices. The features of OASIS modeling for the EBT plasma include: (1) particle balance of the bulk toroidal and electron ring plasma components for experimental (H-H, D-D, He-He etc.) as well as reactor (D-T) devices; (2) energy balance in the bulk and ring plasmas for externally heated or ignition devices; (3) alpha particle effects for reactor devices; (4) auxiliary heating effects, including microwave (ECRH), RF heating (e.g., ICRH), and neutral beam methods; and (5) ignition conditions, including fusion power, alpha power and neutron wall loading. The performance studies using OASIS focussed on variation in plasma and device size and on microwave input power and frequency. An additional study was performed to determine the characteristics of an EBT reactor proof-of-principle device operated with a deuterium-tritium plasma. Sensitivity studies were performed for variation in the input microwave power sharing fractions and the dependence of the bulk n tau scaling law on bulk electron temperature

  2. Engineering challenges encountered in the design of the ELMO BUMPY TORUS proof-of-principle fusion device

    International Nuclear Information System (INIS)

    Dillow, C.F.; Imster, H.F.

    1982-01-01

    This paper first provides a summary of the history and current status of the Elmo Bumpy Torus (EBT) fusion concept. A brief description of the EBT-P is then provided in which the many unique features of this fusion device are highlighted. This description will provide the technical background for the following discussions of some of the more challenging mechanical engineering problems encountered to date in the evolution of the EBT-P design. The problems discussed are: optimization of the device primary structure design, optimization of the superconducting magnet x-ray shield design, design of the liquid helium supply and distribution system, and selection of high vacuum seals and pumps and their protection from the high power microwave environment. The common challenge in each of these design issues was to assure adequate performance at minimum cost

  3. ELMO model predicts the price of electric power

    International Nuclear Information System (INIS)

    Antila, H.

    2001-01-01

    Electrowatt-Ekono has developed a new model, by which it is possible to make long-term prognoses on the development of electricity prices in the Nordic Countries. The ELMO model can be used as an analysis service of the electricity markets and estimation of the profitability of long-term power distribution contracts with different scenarios. It can also be applied for calculation of technical and economical fundamentals for new power plants, and for estimation of the effects of different taxation models on the emissions of power generation. The model describes the whole power generation system, the power and heat consumption and transmission. The Finnish power generation system is based on the Electrowatt-Ekono's boiler database by combining different data elements. Calculation is based on the assumption that the Nordic power generation system is used optimally, and that the production costs are minimised. In practise the effectively operated electricity markets ensure the optimal use of the production system. The market area to be described consists of Finland and Sweden. The spot prices have long been the same. Norway has been treated as a separate market area. The most potential power generation system, the power consumption and the power transmission system are presumed for the target year during a normal rainfall situation. The basic scenario is calculated on the basis of the preconditional data. The calculation is carried out on hourly basis, which enables the estimation of the price variation of electric power between different times during the day and seasons. The system optimises the power generation on the basis of electricity and heat consumption curves and fuel prices. The result is an hourly limit price for electric power. Estimates are presented as standard form reports. Prices are presented as average annuals, in the seasonal base, and in hourly or daily basis for different seasons

  4. Use of advanced programmable logic controllers to monitor and control the Elmo Bumpy Torus-proof-of-principle device

    International Nuclear Information System (INIS)

    Boyd, B.A.

    1983-01-01

    The Elmo Bumpy Torus - Proof-of-Principle (EBT-P) device is designed with an instrumentation and control system based upon the use of an advanced Programmable Logic Controller (PLC). The modern PLC incorporates many advanced programming features not available in earlier PLC's intended for application to conventional relay logic replacement. The additional power and flexibility of these modern PLC's is especially applicable to an experimental device such as EBT-P which is made up of several complex interrelated subsystems whose operational characteristics will be evolving throughout the lifetime of the device. The rationale for the selection of advanced PLC's for EBT-P and the approach taken to design of the software developed to control EBT-P are the topics addressed in this paper

  5. Power balance in ELMO Bumpy Torus: bulk electrons and ions in a 37 kW discharge

    International Nuclear Information System (INIS)

    McNeill, D.H.

    1985-10-01

    The power balance of the bulk electrons and ions in discharges with 37 kW of applied microwave power in the ELMO Bumpy Torus (EBT) is examined in a zero-dimensional model using data on the intensity and linewidth of the molecular and atomic hydrogen emission. At least 60% of the applied power is ultimately dissipated by processes involving the neutral particles, including dissociation of molecules, ionization of and radiation from atoms, and heating of cold electrons produced during atomic ionization. The molecular influx rate and the density of atoms are used independently to determine the bulk electron particle confinement time, and an upper bound estimate is made of the diffusional power loss from the bulk plasma electrons. Parameters derived from the basic spectroscopic data presented in this paper include the neutral atom density 2 - 5x10 10 cm -3 , incident molecular flux 3 - 5x10 15 cm -2 s -1 , bulk ion temperature approx. =3 eV, and particle confinement time <1.1 ms. The bulk electron energy confinement time is 0.7 ms or less in the standard operating regime. Published data on the nonthermal electron and ion populations in the plasma are used to evaluate approximately the overall energy flow in the discharge. 54 refs

  6. Kodud mitme mere ääres / Viivi Variksaar

    Index Scriptorium Estoniae

    Variksaar, Viivi, 1948-

    2001-01-01

    Ameerikas Hilton Headis elavatest väliseestlastest Erle ja Elmo H. Sergost, nende korterist Tallinnas Poska tänaval. Seintel olevad pildid on maalinud ja kodu kujundanud Erle Sergo. Kommenteerinud Elmo H. Sergo, Erle Sergo. 8 ill

  7. Tjoplõi dozhd v zale suda / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2006-01-01

    Mängufilm "Meeletu" : stsenaristid Jaan Tätte, Elmo Nüganen : režissöör Elmo Nüganen : operaator Mait Mäekivi : produtsent Kristian Taska : helilooja Jaak Jürisson : peaosas Rain Simmul : Taska Film - Eesti Televisioon 2006. Võrreldakse näidendi lavastust ja filmi. Arvustuses on Jüri osatäitjaks ekslikult nimetatud lavastuse osatäitjat Allan Noormetsa ( tegelikult Aivar Tommingas)

  8. (Stereo)tüüpide fenomenoloogiast ühiskonnas ja kunstis / Anneli Saro

    Index Scriptorium Estoniae

    Saro, Anneli, 1968-

    2006-01-01

    2005. aastal eesti teatris esietendunud lavastuste näitel - Kauksi Ülle "Taarka" (Vanemuine, lav. Ain Mäeots), A. H. Tammsaare- Elmo Nüganeni "Tõde ja õigus. Teine osa" (Tallinna Linnateater, lav. Elmo Nüganen), Jaan Tätte "Meeletu" (Tallinna Linnateater, lav. Eva Klemets), Arto Paasilinna "Jänese aasta" (Von Krahli Teater, lav. Kristian Smeds), Geraldine Aroni "Minu oivaline lahutus" (Eesti Draamateater, lav. Kaie Mihkelson)

  9. RhoG regulates anoikis through a phosphatidylinositol 3-kinase-dependent mechanism

    International Nuclear Information System (INIS)

    Yamaki, Nao; Negishi, Manabu; Katoh, Hironori

    2007-01-01

    In normal epithelial cells, cell-matrix interaction is required for cell survival and proliferation, whereas disruption of this interaction causes epithelial cells to undergo apoptosis called anoikis. Here we show that the small GTPase RhoG plays an important role in the regulation of anoikis. HeLa cells are capable of anchorage-independent cell growth and acquire resistance to anoikis. We found that RNA interference-mediated knockdown of RhoG promoted anoikis in HeLa cells. Previous studies have shown that RhoG activates Rac1 and induces several cellular functions including promotion of cell migration through its effector ELMO and the ELMO-binding protein Dock180 that function as a Rac-specific guanine nucleotide exchange factor. However, RhoG-induced suppression of anoikis was independent of the ELMO- and Dock180-mediated activation of Rac1. On the other hand, the regulation of anoikis by RhoG required phosphatidylinositol 3-kinase (PI3K) activity, and constitutively active RhoG bound to the PI3K regulatory subunit p85α and induced the PI3K-dependent phosphorylation of Akt. Taken together, these results suggest that RhoG protects cells from apoptosis caused by the loss of anchorage through a PI3K-dependent mechanism, independent of its activation of Rac1

  10. ... vaat kus rist, vajab paikapanemist / Mihkel Mutt

    Index Scriptorium Estoniae

    Mutt, Mihkel, 1953-

    2000-01-01

    William Shakespeare tragöödia "Hamlet" Linnateatris, peaosas Marko Matvere, lavastaja Elmo Nüganen, kunstnik Aime Unt. Esietendus 18. detsembril. Lühiandmed "Hamleti" esmalavastusest Eestis 1913.a. Estonias

  11. Nüganen lavastab taas Tammsaaret / Margus Mikomägi

    Index Scriptorium Estoniae

    Mikomägi, Margus, 1956-

    2009-01-01

    Elmo Nüganen otsustas lavastada Tallinna Linnateatris Anton Hansen Tammsaare romaani "Ma armastasin sakslast". Romaani dramatiseeringu kirjutas lavastaja ise oma lavakooli esimese kursuse üliõpilastele mängimiseks

  12. Gordaja tshaika i dranaja vorona / Eteri Kekelidze

    Index Scriptorium Estoniae

    Kekelidze, Eteri, 1944-

    1999-01-01

    VIII "Baltiiski Dom" 8. - 16. okt. 1998 Sankt-Peterburis. Lavastajapreemia sai Adolf Shapiro lavastuse eest "Kolmekrossiooper" Tallinna Linnateatris. Festivalil osales ka Elmo Nüganeni lavastus "Arkaadia" Peterburi Suures Draamateatris

  13. Shapiro pani Nüganeni Moskva publikule tõtt näkku ütlema / Jaanus Piirsalu

    Index Scriptorium Estoniae

    Piirsalu, Jaanus, 1973-

    2008-01-01

    Moskvas Et Cetera teatris 24. dets. esietendunud Adolf Shapiro lavastusest "451 kraadi Fahrenheiti järgi" Ray Bradbury teose ainetel, peaosas Elmo Nüganen. Refereeritakse vene ajakirjanduses ilmunud arvustusi

  14. Tallinna Linnateater noppis "Tõe ja õiguse" eest auhindu

    Index Scriptorium Estoniae

    2007-01-01

    Anton Hansen Tammsaare "Tõe ja õiguse" neljanda osa lavaversioon tõi Linnateatrile parima lavastaja - Elmo Nüganen, parima naispeaosatäitja - Hele Kõre ja parima naiskõrvalosa auhinna - Evelin Pang

  15. Pronksiööl küpsenud valus tõde / Gerda Kordemets ; intervjueeris Jüri Aarma

    Index Scriptorium Estoniae

    Kordemets, Gerda, 1960-

    2009-01-01

    ETV lavastuslike saadete toimetuse juhataja meenutab Tallinna Linnateatri lavastuse "Karin ja Indrek. Tõde ja õigus" Eesti Televisioonile lindistamist aprillis 2007. Lavastaja Elmo Nüganen, aluseks Tammsaare "Tõe ja õiguse" IV osa

  16. Kuningal on külm / Kadi Herkül

    Index Scriptorium Estoniae

    Herkül, Kadi

    1996-01-01

    Dario Fo 'Elizabeth - naine juhuse tahtel', lavastaja Elmo Nüganen, esietendus Linnateatris 21. sept. 1996. Jaan Kruusvalli 'Hullumeelne professor, tema elukäik', lavastaja Mikk Mikiver, esietendus Draamateatris 21. sept. 1996

  17. Kriitik sinus eneses? / Fagira D. Morti

    Index Scriptorium Estoniae

    Fagira D. Morti, pseud., 1974-

    2005-01-01

    Tallinna Linnateatri otsuste - katkestada ebarahuldava taseme pärast lavastuse "Bernarda Alba maja" lavaletoomine ja edasi lükata lavastuse "Sebastian" esietendus, tagamaid avavad Elmo Nüganen, Eva Klemets ja Kalju Orro

  18. Linnateater toob lavale kuus uut etendust

    Index Scriptorium Estoniae

    2007-01-01

    Tallinna Linnateatri hooaja avas William Shakespeare'i "Eksituste komöödia", mille lavastamisel tegid koostöö Elmo Nüganen ja Stephen Harper Londonist. Ka teistest teatri uue hooaja etendustest tutvustavalt

  19. Iris - nimi marmortahvlilt / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2003-01-01

    Briti kirjanikust Iris Murdochist pajatava inglise-ameerika mängufilmist "Iris" eesti videolevisse jõudmise puhul. Võrreldakse inglise teatrilavastaja Richard Eyre filmidebüüti Elmo Nüganeni debüütfilmiga "Nimed marmortahvlil"

  20. Pust budet bezoblatshnõm nebo nad Baltiiskim domom / Ella Agranovskaja

    Index Scriptorium Estoniae

    Agranovskaja, Ella, 1950-

    2000-01-01

    Teatrifestivali "Baltiiski dom" nimelise medali "Stroitel Baltiiskogo doma" pälvisid teatrikriitik Eteri Kekelidze, lavastaja Elmo Nüganen, endine kultuuriminister Jaak Allik, Vene Draamateatri direktor Aleksandr Iljin, teatrijuht Jaak Viller ja Kultuuriministeeriumi kantsler Margus Allikmaa

  1. "Lavakad" laval - kaheksa kuud enne diplomit / Andres Keil

    Index Scriptorium Estoniae

    Keil, Andres, 1974-

    2007-01-01

    Eesti Muusika ja Teatriakadeemia Lavakunstikooli 23. lennu lavastustest : kaksiklavastus "Pink" VAT Teatris, Mart Kase "Perekond" Eesti Nuku- ja Noorsooteatris ja William Shakespeare'i "Eksituste komöödia" Stephen Harperi ja Elmo Nüganeni lavastuses Hobuveskis

  2. Direct reading fast microwave interferometer for EBT

    International Nuclear Information System (INIS)

    Uckan, T.

    1984-10-01

    A simple and inexpensive 4-mm direct reading fast (rise time approx. 100 μs) microwave interferometer is described. The system is particularly useful for density measurements on the ELMO Bumpy Torus (EBT) during pulsed operation

  3. Voldemar Panso preemia said kaksikvennad Priit ja Märt Pius / Tiiu Laks

    Index Scriptorium Estoniae

    Laks, Tiiu, 1984-

    2010-01-01

    Lavakunstikooli 25. lennu üliõpilased Priit ja Märt Pius pälvisid Voldemar Panso nimelise preemia. Terve kursuse esimene bakalaureuselavastus "Jumala Narride Vennaskond" esietendub 4. detsembril Tallinna Linnateatri Põrgulaval. Lavastas kursuse juhendaja Elmo Nüganen

  4. Tele2 kutsus kliendid teatrisse ja kontsertidele

    Index Scriptorium Estoniae

    2007-01-01

    Suvel kutsus Tele 2 kliendid Victor Hugo loo "Jumalaema kiriku kellamees" muusikalisele vaatemängule Tartus (lavastajad Urmas Lennuk ja Andres Dvinjaninov), Muhu Tulevikumuusika festivalile "Juu Jääb" ja Tallinna Linnateatri suvelavastusele "Ronk" (lavastaja Elmo Nüganen)

  5. Soome levitaja loodab ületada ühe kuuga 50 000 vaataja piiri / Tarmo Virki

    Index Scriptorium Estoniae

    Virki, Tarmo

    2002-01-01

    Filmi "Nimed marmortahvlil" levitamisest Soomes ja eilsest pressilinastusest ning sellele järgnenud pressikonverentsist, kus osalesid ka Elmo Nüganen ja näitlejad Hele Kõre, Priit Võigemast ja Peter Franzen ning Soome-poolne produtsent Ilkka Y.L. Matila

  6. Nüganen räägib "Marmortahvli" sünniloo / Piret Jaaks

    Index Scriptorium Estoniae

    Jaaks, Piret, 1980-

    2003-01-01

    Mängufilm "Nimed marmortahvlil" jõuab nii VHS-kasseti kui DVD-plaadina müügile. Lisaks filmile ilmub DVDl lavastaja Elmo Nüganeni ja mõnede näitlejate poolt kommenteeritud filmiversioon ning Anu Auna dokumentaalfilm filmi tegemisest

  7. Saage tuttavaks - EMTA lavakunstikooli 25. lend! / Anu Lamp

    Index Scriptorium Estoniae

    Lamp, Anu, 1958-

    2010-01-01

    Eesti Muusika- ja Teatriakadeemia Lavakunstikooli 25. lennu tutvustus. 4. dets. esietendub Tallinna Linnateatris 25. lennu bakalauruselavastus "Jumala Narride Vennaskond". Lavastaja ja kunstnik Elmo Nüganen. Inglise näitekirjaniku Peter Barnesi loomingust ja näidendist "Jumala Narride Vennaskond" ("Red Noses")

  8. 'Mauruse kool'. Priit Pedajase dramatiseering ja lavastus Draamateatris / Mihkel Mutt

    Index Scriptorium Estoniae

    Mutt, Mihkel, 1953-

    1996-01-01

    A. H. Tammsaare "Tõe ja õiguse" II osa järgi ja W. M. Bauer 'Ühe võõra silmades' Eesti Draamateatris, lavastaja Katri Kaasik-Aaslav, Anton Tšehhovi motiividel "Pianoola ehk mehhaaniline klaver" Tallinna Linnateatris, lavastaja Elmo Nüganen

  9. "Puhastuse" esimesed osatäitjad teada / Kaarel Kressa

    Index Scriptorium Estoniae

    Kressa, Kaarel, 1983-

    2011-01-01

    Eesti-Soome koostöös valmiva Antti Jokise filmis "Puhastus" mängib vana Aliidet Liisi Tandefelt, Aliidet nooruspäevil Laura Birn, Hansu Peter Franzén, Martinit Tommi Korpela, Aliide vanemaid Anne Reemann ja Elmo Nüganen

  10. Tallinna Linnateater Stuttgardi festivalil

    Index Scriptorium Estoniae

    2000-01-01

    Tallinna Linnateater mängib 29. ja 30. nov. Saksamaal Stuttgardi rahvusvahelisel teatrifestivalil Jaan Tätte lavastust "Ristumine peateega". Stuttgardi Riiklik Teater ootab Tallinna Linnateatrit külla saksa lavastaja Andrea Mosese lavastusega "Clavigo" ja Elmo Nüganeni lavastusega "Pianoola ehk Mehhaaniline klaver"

  11. CAMAC based inter-compter communications system

    International Nuclear Information System (INIS)

    Greenwood, D.E.; Burris, R.D.; Young, K.G.

    1981-10-01

    We have used CAMAC hardware to provide communications between dissimilar computers for the ELMO Bumpy Torus (EBT) experiment. The software supports file and individual message transfers. The system has proven to be both reliable and fast, with transmission rates of about 36,000 baud

  12. Linnateater - 16 nimetust / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2006-01-01

    Tallinna Linnateatri viimase kümne aasta lavastustest ja lavastajatest - Elmo Nüganen, Jaanus Rohumaa, Mart Koldits, Eva Klemets ja külalislavastajast Adolf Shapirost. Pikemalt peatutakse lavastustel "Pianoola ehk Mehhaaniline klaver", "Tõde ja õigus. Teine osa", Tshapajev ja Pustota", "Et keegi mind valvaks"

  13. Uus näitlejapõlvkond endale armu ei anna / Margit Tõnson

    Index Scriptorium Estoniae

    Tõnson, Margit, 1978-

    2010-01-01

    Eesti Muusika- ja Teatriakadeemia lavakunstikooli XXV lennu bakalaureuselavastus "Jumala narride Vennaskond" Tallinna Linnateatris. Lavastaja Elmo Nüganen, autor Peter Barnes. Juhan Ulfsaki lavastusest "Idioodid" Lars von Trieri samanimelise filmi järgi Von Krahli teatris. Mängivad TÜ Viljandi Kultuuriakadeemia teatrikunsti 8. lennu Von Krahli kursuslased

  14. The compressional Alfven instability in ECRH plasmas

    International Nuclear Information System (INIS)

    El Nadi, A.

    1982-01-01

    It is shown that the hot electron component present in an electron cyclotron resonance heated plasma can destabilize the compressional Alfven wave if β of the background plasma exceeds a certain limit. The relevance of the result to the Elmo Bumpy Torus experiment is discussed. (author)

  15. Kas tasemetööd täidavad oma eesmärki? / Marge Lepik, Kristi Mere, Merike Haas...[jt.

    Index Scriptorium Estoniae

    2009-01-01

    Küsimusele vastavad Lääne-Viru maavalitsuse haridusosakonna juhataja Marge Lepik, Haridus- ja Teadusministeeriumi välishindamisosakonna peaekspert Kristi Mere, Viira kooli klassiõpetaja Merike Haas, Rääma põhikooli direktor Elmo Joa ja Tallinna Ülikooli Haapsalu kolledži õppejõud Sirje Piht

  16. EBT-P project status report

    International Nuclear Information System (INIS)

    1983-11-01

    This Elmo Bumpy Torus Report describes the status of the EBT-P Project in September 1983 after phasedown of the Title II design effort. The report is intended to be a principle source of guidance in the event of a decision to resume work on the project

  17. Vargamäelt leigust ei leitud / Jan Kaus

    Index Scriptorium Estoniae

    Kaus, Jan, 1971-

    2008-01-01

    Vargamäel 21. juunil 22 tundi kestnud maratonetendusest Tammsaare "Tõe ja õiguse" põhjal - Elmo Nüganeni lavastused "Tõde ja õigus. Teine osa", "Karin. Indrek. Tõde ja õigus. 4" ja "Wargamäe Wabariik" (III osa) ning Jaanus Rohumaa lavastus "Vargamäe kuningriik" (I ja V osa)

  18. Hazard evaluation of inorganics, singly and in mixtures, to Flannelmouth Sucker Catostomus latipinnis in the San Juan River, New Mexico

    Science.gov (United States)

    Hamilton, S.J.; Buhl, K.J.

    1997-01-01

    Larval flannelmouth sucker (Catostomus latipinnis) were exposed to arsenate, boron, copper, molybdenum, selenate, selenite, uranium, vanadium, and zinc singly, and to five mixtures of five to nine inorganics. The exposures were conducted in reconstituted water representative of the San Juan River near Shiprock, New Mexico. The mixtures simulated environmental ratios reported for sites along the San Juan River (San Juan River backwater, Fruitland marsh, Hogback East Drain, Mancos River, and McElmo Creek). The rank order of the individual inorganics, from most to least toxic, was: copper > zinc > vanadium > selenite > selenate > arsenate > uranium > boron > molybdenum. All five mixtures exhibited additive toxicity to flannelmouth sucker. In a limited number of tests, 44-day-old and 13-day-old larvae exhibited no difference in sensitivity to three mixtures. Copper was the major toxic component in four mixtures (San Juan backwater, Hogback East Drain, Mancos River, and McElmo Creek), whereas zinc was the major toxic component in the Fruitland marsh mixture, which did not contain copper. The Hogback East Drain was the most toxic mixture tested. Comparison of 96-h LC50values with reported environmental water concentrations from the San Juan River revealed low hazard ratios for arsenic, boron, molybdenum, selenate, selenite, uranium, and vanadium, moderate hazard ratios for zinc and the Fruitland marsh mixture, and high hazard ratios for copper at three sites and four environmental mixtures representing a San Juan backwater, Hogback East Drain, Mancos River, and McElmo Creek. The high hazard ratios suggest that inorganic contaminants could adversely affect larval flannelmouth sucker in the San Juan River at four sites receiving elevated inorganics.

  19. Kuidas staarnäitlejatest abielupaar vangi pandi / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2010-01-01

    Eesti Draamateatris loeti näidendit Mari Möldre ja Ruut Tarmo vangistamisest Stalini ajal. Dokumendid leidis arhiividest ajaloolane Mart Laar, näidendi "Mari ja Ruut" autorid on lavakunstikooli tudengid Diana Leesalu ja Paavo Piik. Möldre rolli luges Anu Lamp, Tarmo rolli Elmo Nüganen, lugemise lavastas Merle Karusoo

  20. Muusikapassioon mõttepeeglis. Täna kõlab "Stabat Mater" / Anne Peäske

    Index Scriptorium Estoniae

    Peäske, Anne, 1946-

    2005-01-01

    Arvo Pärdi "Passio" ettekandest 11.sept. Rakvere Kolmainu kirikus. Elmo Lööve, Raivo Palmaru, Jaan Rääts, Toivo Tulev, Aarne Talvik, Ingmar Kurg, Olev Oja ja Eleonora Pärt Arvo Pärdi muusikast. A. Pärdi "Stabat Mater" ansambli Theatre of Voices esituses 14. sept. Rakvere Kolmainu kirikus

  1. Raznõje litsa Indreka Paasa / Eteri Kekelidze

    Index Scriptorium Estoniae

    Kekelidze, Eteri, 1944-

    2008-01-01

    Vargamäel 22 tundi kestnud maratonetendusest Tammsaare "Tõe ja õiguse" põhjal - Elmo Nüganeni lavastused "Tõde ja õigus. Teine osa", "Karin. Indrek. Tõde ja õigus. 4" ja "Wargamäe Wabariik" (III osa) ning Jaanus Rohumaa lavastus "Vargamäe kuningriik" (I ja V osa). Pikemalt "Wargamäe Wabariigi" lavastusest

  2. "Sakala" fotograaf pälvis tähelepanu

    Index Scriptorium Estoniae

    2006-01-01

    Eesti Ajalehtede Liidu pressipreemia fotožürii valis välja 2005. a. paremad uudis- ja olemusfotod. Maakonnalehtede parima uudisfoto tiitlile pretendeerivad Elmo Riigi ja Margus Ansu fotod, parima olemusfoto tiitlile Ants Liiguse, Tairo Lutteri ja Sille Annuki fotod. Žürii koosseis. Võitjad kuulutatakse välja 2. märtsil

  3. Radial mode structure of curvature-driven instabilities in EBT

    International Nuclear Information System (INIS)

    Spong, D.A.

    1983-01-01

    Viewgraphs describe the theoretical treatment of the radial mode structure of plasma instabilities in the Elmo Bumpy Torus. The calculation retains nonlocal structure of the modes, connects inner and outer ring regions together, uses a self-consistent finite β, includes the relativistic effects for the hot electron ring, and examines a wide range of parameters

  4. Gombrowicz, järjest lahjemas kastmes. Laulatusest pulmadeni ja neitsilikkusest Poolas / Hendrik Lindepuu

    Index Scriptorium Estoniae

    Lindepuu, Hendrik, 1958-

    2006-01-01

    Seitsmendast Gombrowiczi rahvusvahelisest teatrifestivalist: W. Gombrowiczi "Laulatus (lavastaja Elmo Nüganen, Toruni teater), S. Wyspianski "Vabastamine" (lavastaja Mikolaj Grabowski, Krakowi Stary Teater), W. Gombrowiczi "Neitsilikkus" (lavastaja Przemyslaw Wisniewski, Alina Czyzewska esituses), "Gombrowiczi tüübid" (Przemyslaw Gasiorowiczi esituses), W. Gombrowiczi "Ferdydurke" (lavastaja Serhij Proskurnia, Ukraina Tsherkassõ Shevtshenko nimeline teater), W. Gombrowiczi "Saladus" (Poznani teater Porywacze Cial )

  5. CED-10/Rac1 regulates endocytic recycling through the RAB-5 GAP TBC-2.

    Directory of Open Access Journals (Sweden)

    Lin Sun

    Full Text Available Rac1 is a founding member of the Rho-GTPase family and a key regulator of membrane remodeling. In the context of apoptotic cell corpse engulfment, CED-10/Rac1 acts with its bipartite guanine nucleotide exchange factor, CED-5/Dock180-CED-12/ELMO, in an evolutionarily conserved pathway to promote phagocytosis. Here we show that in the context of the Caenorhabditis elegans intestinal epithelium CED-10/Rac1, CED-5/Dock180, and CED-12/ELMO promote basolateral recycling. Furthermore, we show that CED-10 binds to the RAB-5 GTPase activating protein TBC-2, that CED-10 contributes to recruitment of TBC-2 to endosomes, and that recycling cargo is trapped in recycling endosomes in ced-12, ced-10, and tbc-2 mutants. Expression of GTPase defective RAB-5(Q78L also traps recycling cargo. Our results indicate that down-regulation of early endosome regulator RAB-5/Rab5 by a CED-5, CED-12, CED-10, TBC-2 cascade is an important step in the transport of cargo through the basolateral recycling endosome for delivery to the plasma membrane.

  6. Teatriankeet 2007/2008

    Index Scriptorium Estoniae

    2008-01-01

    Teatrihooaega 2007/2008 hindavad teatrikriitikud, -loolased, -uurijad. Nimetatud ka parimad lavastused 2007/2008 - A. H. Tammsaare / Urmas Lennuk "Wargamäe Wabariik" (Tallinna Linnateater, lav. Elmo Nüganen), Tiit Ojasoo ja Ene-Liis Semper "Ruja" (Vanemuine, lav. Tiit Ojasoo), Veljo Tormis "Eesti meeste laulud" (Von Krahli Teater ja Nargen Opera, lav. Peeter Jalaks, muusikaline juht Tõnu Kaljuste), Anton Tshehhov "Kajakas" (Endla, lav. Andres Noormets)

  7. Ööpäeva väldanud etendused keerasid näitlejate ja publiku elurütmi pea peale / Marika Rajamäe, Merili Nikkolo

    Index Scriptorium Estoniae

    Rajamäe, Marika, 1952-

    2008-01-01

    Vargamäel 22 tundi kestnud maratonetendusest Tammsaare "Tõe ja õiguse" põhjal - Elmo Nüganeni lavastused "Tõde ja õigus. Teine osa", "Karin. Indrek. Tõde ja õigus. 4" ja "Wargamäe Wabariik" (III osa) ning Jaanus Rohumaa lavastus "Vargamäe kuningriik" (I ja V osa). Reportaaž on tähtsamatest hetkedest alates 21. juuni kell 11.00 kuni 22. juuni 10.00-ni

  8. Theoretical studies of Elmo Bumpy Torus. Annual report

    International Nuclear Information System (INIS)

    1984-01-01

    The work was divided into four basic areas. Studies of the effect of waves on stability and transport considered the possibility of using radio frequency waves to stabilize interchange modes, as well as the general problem of influencing plasma transport by wave absorption. Studies related to wave heating of plasmas considered nonlinear effects such as mode conversion and parametric absorption, along with studies of the structure of ion cyclotron waves in a strongly bumpy geometry. Ring physics studies added nonadiabaticity and whistler instabilities to the model, producing a fairly realistic picture of energy balance, power requirements, and scaling for hot electron rings. Finally, studies analyzing EBT transport data were performed, with emphasis on testing various hypotheses for apparent anomalies in the EBT

  9. Pletjenõi tshemodan iz vinogradnoi lozõ / Nikolai Hrustaljov

    Index Scriptorium Estoniae

    Hrustaljov, Nikolai

    2003-01-01

    Musta mere ääres Anapas lõppenud rahvusvahelisel filmifestivalil "Kinoshokk" sai Elmo Nüganeni "Nimed marmortahvlil" žürii eripreemia. Võitis Tadzhikistani režissööri Djamshed Usmonovi mitme riigi ühistööna valminud "Ingel paremal". Režiipreemia sai Aleksei German noorema "Viimane rong" ("Posledni pojezd"), Pavel Luspekajevi nimelise preemia "Au ja väärikuse eest" sai näitleja Sergei Jurski

  10. Ehitaja Aastaehitised 2003 on selgunud

    Index Scriptorium Estoniae

    2004-01-01

    Aastaehitised 2003: uusehitis - Laulasmaa SPA & Konverentsihotell (arhitekt Priit Ehala, AB Ehala & Irik, projekteerija Projektbüroo Teinos, ehitaja FKSM), renoveeritud ehitis - korterelamu Tallinnas Piiskopi t. 2 (arhitekt Elmo Raukas, sisearhitekt Heli Eensalu, projektterija ja ehitaja Restor), rajatis - Turu sild Tartus (arhitektuurne lahendus: Tartu Arhitektuuribüroo, vantsüsteemide arvutused: Ehituse & Tarkvara Inseneribüroo), eramu - Merirahu eramu (arhitekt Tarmo Piirmets, projekteerija Estkonsult, ehitaja E-Betoonelement). 4 ill

  11. Draamafestival toob Eestisse Elmo Nüganeni tipplavastuse / Hendrik Lindepuu

    Index Scriptorium Estoniae

    Lindepuu, Hendrik

    2005-01-01

    Selle aasta Draama festivali üheks väliskülaliseks on Poola Toruni Wilam Horzyca teater lavastusega "Laulatus". W. Gombrowiczi näidendi lavastajaks on Tallinna Linnateatri peanäitejuht E. Nüganen

  12. Curvature-driven instabilities in the Elmo Bumpy Torus (EBT)

    International Nuclear Information System (INIS)

    Abe, H.; Spong, D.A.; Antonsen, T.M. Jr.; Tsang, K.T.; Nguyen, K.T.

    1982-01-01

    Curvature-driven instabilities are analyzed for an EBT configuration which consists of plasma interacting with a hot electron ring whose drift frequencies are larger than the growth rates predicted from conventional magnetohydrodynamic (MHD) theory. Stability criteria are obtained for five possible modes: the conventional hot electron interchange, a high-frequency hot electron interchange (at frequencies greater than the ion-cyclotron frequency), a compressional instability, a background plasma interchange, and an interacting pressure-driven interchange. A wide parameter regime for stable operation is found, which, however, severely deteriorates for a band of intermediate mode numbers. Finite Larmor radius effects can eliminate this deterioration; moreover, all short-wavelength curvature-driven modes are stabilized if the hot electron Larmor radius rho/sub h/ satisfies (kappa/sub perpendicular/rho/sub h/) 2 > 2Δ/[Rβ/sub h/(1 + P'/sub parallel//P'/sub perpendicular/)], where kappa/sub perpendicular/ is the transverse wavenumber, Δ is the ring half-width, R is the mid-plane radius of curvature, β/sub h/ is the hot electron beta value, and P' is the pressure gradient. Resonant wave-particle instabilities predicted by a new low frequency variational principle show that a variety of remnant instabilities may still persist

  13. A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs.

    Science.gov (United States)

    Lu, Mingjian; Kinchen, Jason M; Rossman, Kent L; Grimsley, Cynthia; Hall, Matthew; Sondek, John; Hengartner, Michael O; Yajnik, Vijay; Ravichandran, Kodi S

    2005-02-22

    CDM (CED-5, Dock180, Myoblast city) family members have been recently identified as novel, evolutionarily conserved guanine nucleotide exchange factors (GEFs) for Rho-family GTPases . They regulate multiple processes, including embryonic development, cell migration, apoptotic-cell engulfment, tumor invasion, and HIV-1 infection, in diverse model systems . However, the mechanism(s) of regulation of CDM proteins has not been well understood. Here, our studies on the prototype member Dock180 reveal a steric-inhibition model for regulating the Dock180 family of GEFs. At basal state, the N-terminal SH3 domain of Dock180 binds to the distant catalytic Docker domain and negatively regulates the function of Dock180. Further studies revealed that the SH3:Docker interaction sterically blocks Rac access to the Docker domain. Interestingly, ELMO binding to the SH3 domain of Dock180 disrupted the SH3:Docker interaction, facilitated Rac access to the Docker domain, and contributed to the GEF activity of the Dock180/ELMO complex. Additional genetic rescue studies in C. elegans suggested that the regulation of the Docker-domain-mediated GEF activity by the SH3 domain and its adjoining region is evolutionarily conserved. This steric-inhibition model may be a general mechanism for regulating multiple SH3-domain-containing Dock180 family members and may have implications for a variety of biological processes.

  14. Characterization of Mesa Verde Black-on-white ceramics from southwestern Colorado using NAA

    Energy Technology Data Exchange (ETDEWEB)

    Glowacki, D M; Neff, H; Glascock, M D [Missouri Univ., Columbia, MO (United States). Research Reactor Facility

    1995-10-01

    Sixty Mesa Verde variety Black-on-white bowls from Castle Rock Pueblo (5MT 1825) and Sand Canyon Pueblo (5MT765) in southwestern Colorado were chemically characterized using neutron activation analysis. Eleven clay sources local to the sites in the McElmo Drainage area were also analyzed. The results revealed two distinct compositional groups containing relative frequencies that imply local production. The occurrence of trade between the two sites was also identified. (author). 20 refs., 5 figs., 2 tabs.

  15. The Antiaircraft Journal. Volume 93, Number 6, November-December 1950

    Science.gov (United States)

    1950-12-01

    compromise. Russia and the satellites deposited a reser- vation against freeing the original Detaining Power from responsibility. HUl\\ IANE TREATMENT OF...H., 543 Flynn Ave., Redwood City, Calif. Cox, Thomas R., 46 Maitland Rd., Stamford, Conn. DeRita, Joseph, Box 83, Lafayette, R. I. DiEnno, John, Jr... Ian 2-40 Broudy, Harold, Capt. 2- 2 Cunningham, Elmo E., 1st Lt. 5- 7 Currie, A. A., Lt. Col. 1-26 Dillon, Joseph V., Brig. Gen 6-34 Dineley, R. L., M

  16. Teatri aastaauhindade nominendid

    Index Scriptorium Estoniae

    2006-01-01

    Lavastajaauhind : Merle Karusoo, Elmo Nüganen, Tiit Ojasoo, Ene-Liis Semper, Kristian Smeds, Hendrik Toompere jun, Ingomar Vihmar ; kunstnikuauhind : Iir Hermeliin, Liina Keevallik, Ene-Liis Semper, Aime Unt, Ervin Õunapuu ; naisnäitleja auhind : Ülle Kaljuste, Kaie Mihkelson, Harriet Toompere, Marika Vaarik, Liina Vahtrik ; meesnäitleja auhind : Ain Lutsepp, Rein Oja, Rain Simmul, Tarvo Sõmer, Tambet Tuisk, Aarne Üksküla ; Balleti- ja tantsuteater : Marina Tshirkova, Seki Hirotaka, Mari Savitski, Oksana Titova, Taavet Jansen, Sasha Pepeljajev, Katrin Essenson ja Tantsuteater Fine 5

  17. Linnateatri triumf : Draama 99 külalised hindasid eesti teatri laadirikkaks / Meelis Kapstas, Andres Laasik

    Index Scriptorium Estoniae

    Kapstas, Meelis, 1963-

    1999-01-01

    Teatrifestivali Draama 99 preemiad : lavastajapreemiad: Elmo Nüganen ("Kuritöö ja karistus"), Priit Pedajas ("Mao tee kalju peal"), naisnäitleja preemiad : Merle Jääger ("Omavahelisi jutuajamisi tädi Elliga"), Anne Reeman ("Kolmekrossiooper"), meesnäitleja preemia : Indrek Sammul ("Kuritöö ja karistus"),kõrvalosatäitja preemiad : Anu Lamp(" Kolmekrossiooper " ja "Kuritöö ja karistus"), Peeter Tammearu ("Kolmekrossiooper", "Kuritöö ja karistus"), kunstnikupreemia : Vladimir Anshon ("Kolmekrossiooper"), žürii eripreemiad : Merle Karusoo ("Küüdipoisid"), Rein Agur ("Cymbeline")

  18. Tallinna Linnateater lõikas Tartus loorbereid : parimad näitlejad on Jääger, Reemann ja Sammul / Aigi Viira

    Index Scriptorium Estoniae

    Viira, Aigi

    1999-01-01

    Teatrifestivali Draama 99 preemiad : lavastajapreemiad: Elmo Nüganen ("Kuritöö ja karistus"), Priit Pedajas ("Mao tee kalju peal"), naisnäitleja preemiad : Merle Jääger ("Omavahelisi jutuajamisi tädi Elliga"), Anne Reeman ("Kolmekrossiooper"), meesnäitleja preemia : Indrek Sammul ("Kuritöö ja karistus"), kõrvalosatäitja preemiad : Anu Lamp (" Kolmekrossiooper " ja "Kuritöö ja karistus"), Peeter Tammearu ("Kolmekrossiooper", "Kuritöö ja karistus"), kunstnikupreemia : Vladimir Anshon ("Kolmekrossiooper"), žürii eripreemiad : Merle Karusoo ("Küüdipoisid"), Rein Agur ("Cymbeline")

  19. "Drama - 99 " : vzgljad so storonõ / Eteri Kekelidze

    Index Scriptorium Estoniae

    Kekelidze, Eteri, 1944-

    1999-01-01

    Teatrifestivali Draama 99 preemiad : lavastajapreemiad: Elmo Nüganen ("Kuritöö ja karistus"), Priit Pedajas ("Mao tee kalju peal"), naisnäitleja preemiad : Merle Jääger ("Omavahelisi jutuajamisi tädi Elliga"), Anne Reeman ("Kolmekrossiooper"), meesnäitleja preemia : Indrek Sammul ("Kuritöö ja karistus"), kõrvalosatäitja preemiad : Anu Lamp (" Kolmekrossiooper" ja "Kuritöö ja karistus"), Peeter Tammearu ("Kolmekrossiooper", "Kuritöö ja karistus"), kunstnikupreemia : Vladimir Anshon ("Kolmekrossiooper"), žürii eripreemiad : Merle Karusoo ("Küüdipoisid"), Rein Agur ("Cymbeline")

  20. What preschool children do and do not do with ungrammatical word orders

    OpenAIRE

    Abbot-Smith, Kirsten; Lieven, Elena; Tomasello, Michael

    2001-01-01

    Akhtar [J. Child Lang. 26 (1999) 339.] found that when 4-year-old English-speaking children hear novel verbs in transitive utterances with ungrammatical word orders (e.g., Elmo the tree meeked), they correct them to canonical SVO order almost all of the time. However, when 3-year-olds and older 2-year-olds hear these same utterances, they waver between correcting and using the ungrammatical ordering. In the current study, we adapted this task for children at 2;4, using an intransitive constru...

  1. Advanced fusion concepts program

    International Nuclear Information System (INIS)

    Dove, W.F.

    1978-01-01

    While the prospects for the eventual development of a tokamak-based fusion reactor appear promising at the present time, the Department of Energy maintains a vigorous program in alternate magnetic fusion concepts. Several of the concepts presently supported include the toroidal reversed field pinch, Tormac, Elmo Bumpy Torus, and various linear options. Recent technical accomplishments and program evaluations indicate that the possibility now exists for undertaking the next development stage, a proof-of-principle experiment, for a few of the most promising alternate concepts

  2. Teatri aastaauhindadele kandideerijad selgunud

    Index Scriptorium Estoniae

    2006-01-01

    Lavastajaauhind : Merle Karusoo, Elmo Nüganen, Tiit Ojasoo, Ene-Liis Semper, Kristian Smeds, Hendrik Toompere jun, Ingomar Vihmar ; kunstnikuauhind : Iir Hermeliin, Liina Keevallik, Ene-Liis Semper, Aime Unt, Ervin Õunapuu ; naisnäitleja auhind : Ülle Kaljuste, Kaie Mihkelson, Harriet Toompere, Marika Vaarik, Liina Vahtrik ; meesnäitleja auhind : Ain Lutsepp, Rein Oja, Rain Simmul, Tarvo Sõmer, Tambet Tuisk, Aarne Üksküla ; Balleti- ja tantsuteater : Marina Tshirkova, Seki Hirotaka, Mari Savitski, Oksana Titova, Taavet Jansen, Sasha Pepeljajev, Katrin Essenson ja Tantsuteater Fine 5

  3. Determining CO2 storage potential during miscible CO2 enhanced oil recovery: Noble gas and stable isotope tracers

    Science.gov (United States)

    Shelton, Jenna L.; McIntosh, Jennifer C.; Hunt, Andrew; Beebe, Thomas L; Parker, Andrew D; Warwick, Peter D.; Drake, Ronald; McCray, John E.

    2016-01-01

    Rising atmospheric carbon dioxide (CO2) concentrations are fueling anthropogenic climate change. Geologic sequestration of anthropogenic CO2 in depleted oil reservoirs is one option for reducing CO2 emissions to the atmosphere while enhancing oil recovery. In order to evaluate the feasibility of using enhanced oil recovery (EOR) sites in the United States for permanent CO2 storage, an active multi-stage miscible CO2flooding project in the Permian Basin (North Ward Estes Field, near Wickett, Texas) was investigated. In addition, two major natural CO2 reservoirs in the southeastern Paradox Basin (McElmo Dome and Doe Canyon) were also investigated as they provide CO2 for EOR operations in the Permian Basin. Produced gas and water were collected from three different CO2 flooding phases (with different start dates) within the North Ward Estes Field to evaluate possible CO2 storage mechanisms and amounts of total CO2retention. McElmo Dome and Doe Canyon were sampled for produced gas to determine the noble gas and stable isotope signature of the original injected EOR gas and to confirm the source of this naturally-occurring CO2. As expected, the natural CO2produced from McElmo Dome and Doe Canyon is a mix of mantle and crustal sources. When comparing CO2 injection and production rates for the CO2 floods in the North Ward Estes Field, it appears that CO2 retention in the reservoir decreased over the course of the three injections, retaining 39%, 49% and 61% of the injected CO2 for the 2008, 2010, and 2013 projects, respectively, characteristic of maturing CO2 miscible flood projects. Noble gas isotopic composition of the injected and produced gas for the flood projects suggest no active fractionation, while δ13CCO2 values suggest no active CO2dissolution into formation water, or mineralization. CO2 volumes capable of dissolving in residual formation fluids were also estimated along with the potential to store pure-phase supercritical CO2. Using a combination

  4. Microbial potential for carbon and nutrient cycling in a geogenic supercritical carbon dioxide reservoir.

    Science.gov (United States)

    Freedman, Adam J E; Tan, BoonFei; Thompson, Janelle R

    2017-06-01

    Microorganisms catalyze carbon cycling and biogeochemical reactions in the deep subsurface and thus may be expected to influence the fate of injected supercritical (sc) CO 2 following geological carbon sequestration (GCS). We hypothesized that natural subsurface scCO 2 reservoirs, which serve as analogs for the long-term fate of sequestered scCO 2 , harbor a 'deep carbonated biosphere' with carbon cycling potential. We sampled subsurface fluids from scCO 2 -water separators at a natural scCO 2 reservoir at McElmo Dome, Colorado for analysis of 16S rRNA gene diversity and metagenome content. Sequence annotations indicated dominance of Sulfurospirillum, Rhizobium, Desulfovibrio and four members of the Clostridiales family. Genomes extracted from metagenomes using homology and compositional approaches revealed diverse mechanisms for growth and nutrient cycling, including pathways for CO 2 and N 2 fixation, anaerobic respiration, sulfur oxidation, fermentation and potential for metabolic syntrophy. Differences in biogeochemical potential between two production well communities were consistent with differences in fluid chemical profiles, suggesting a potential link between microbial activity and geochemistry. The existence of a microbial ecosystem associated with the McElmo Dome scCO 2 reservoir indicates that potential impacts of the deep biosphere on CO 2 fate and transport should be taken into consideration as a component of GCS planning and modelling. © 2017 The Authors. Environmental Microbiology published by Society for Applied Microbiology and John Wiley & Sons Ltd.

  5. Trends and developments in magnetic confinement fusion reactor concepts

    International Nuclear Information System (INIS)

    Baker, C.C.; Carlson, G.A.; Krakowski, R.A.

    1981-01-01

    An overview is presented of recent design trends and developments in reactor concepts for magnetic confinement fusion. The paper emphasizes the engineering and technology considerations of commercial fusion reactor concepts. Emphasis is placed on reactors that operate on the deuterium/tritium/lithium fuel cycle. Recent developments in tokamak, mirror, and Elmo Bumpy Torus reactor concepts are described, as well as a survey of recent developments on a wide variety of alternate magnetic fusion reactor concepts. The paper emphasizes recent developments of these concepts within the last two to three years

  6. Data format translation routines

    International Nuclear Information System (INIS)

    Burris, R.D.

    1981-02-01

    To enable the effective connection of several dissimilar computers into a network, modification of the data being passed from one computer to another may become necessary. This document describes a package of routines which permit the translation of data in PDP-8 formats to PDP-11 or DECsystem-10 formats or from PDP-11 format to DECsystem-10 format. Additional routines are described which permit the effective use of the translation routines in the environment of the Fusion Energy Division (FED) network and the Elmo Bumpy Torus (EBT) data base

  7. Evelin Ilves esineb Moskvas konverentsil / Jaanus Piirsalu

    Index Scriptorium Estoniae

    Piirsalu, Jaanus, 1973-

    2008-01-01

    Proua Evelin Ilves esineb Moskvas ülevenemaalises väliskirjanduse raamatukogus toimuval rahvusvahelisel konverentsil "Naised muutuvas maailmas" ettekandega "Kas meeste tervis on naiste probleem?" Proua E. Ilvese esinemise initsiaator on Moskva rahvusvahelisse naisteklubisse kuuluv Eesti suursaadik Marina Kaljurand. Proua E. Ilves külastab ka Teemandifondi Kremlis ja vaatab Et Cetera teatris Adolf Šapiro lavastatud "451 kraadi Fahrenheiti", kus peaosa mängib Elmo Nüganen. Vt. samas: Esimene esimene leedi Moskvas. Teadaolevalt on proua E. Ilves esimene Eesti riigipea abikaasa, kes ametlikult külastab oma abikaasa ametiaja jooksul Venemaa pealinna

  8. X-ray Constrained Extremely Localized Molecular Orbitals: Theory and Critical Assessment of the New Technique.

    Science.gov (United States)

    Genoni, Alessandro

    2013-07-09

    Following the X-ray constrained wave function approach proposed by Jayatilaka, we have devised a new technique that allows to extract molecular orbitals strictly localized on small molecular fragments from sets of experimental X-ray structure factors amplitudes. Since the novel strategy enables to obtain electron distributions that have quantum mechanical features and that can be easily interpreted in terms of traditional chemical concepts, the method can be also considered as a new useful tool for the determination and the analysis of charge densities from high-resolution X-ray experiments. In this paper, we describe in detail the theory of the new technique, which, in comparison to our preliminary work, has been improved both treating the effects of isotropic secondary extinctions and introducing a new protocol to halt the fitting procedure against the experimental X-ray scattering data. The performances of the novel strategy have been studied both in function of the basis-sets flexibility and in function of the quality of the considered crystallographic data. The tests performed on four different systems (α-glycine, l-cysteine, (aminomethyl)phosphonic acid and N-(trifluoromethyl)formamide) have shown that the achievement of good statistical agreements with the experimental measures mainly depends on the quality of the crystal structures (i.e., geometry positions and thermal parameters) used in the X-ray constrained calculations. Finally, given the reliable transferability of the obtained Extremely Localized Molecular Orbitals (ELMOs), we envisage to exploit the novel approach to construct new ELMOs databases suited to the development of linear-scaling methods for the refinement of macromolecular crystal structures.

  9. Selection of vacuum seals for EBT-P

    International Nuclear Information System (INIS)

    Dillow, C.F.; Adlon, G.L.; Stubblefield, V.E.

    1981-01-01

    Elmo Bumpy Torus Proof of Principle (EBT-P) is a magnetic fusion RandD facility being constructed by McDonnell Douglas Astronautics Company - St. Louis Division of Oak Ridge National Laboratory (ORNL). EBT-P is a truly unique fusion device requiring careful consideration in selecting both the primary vacuum seals on the toroidal vessel and the secondary vacuum seals in components such as vacuum pumps and and valves. The vacuum seal environment is described and the considerations in vacuum seal selection fully discussed. Methods for protecting vacuum seals in pumps and valves from the microwave environments are also presented

  10. Elmo Nüganeni "Laulatus" võitis Poolas neli preemiat / Andres Keil

    Index Scriptorium Estoniae

    Keil, Andres, 1974-

    2005-01-01

    E. Nüganeni Poolas, Toruni teatris valminud lavastus - W. Gombrowiczi "Laulatus"- pälvis Opole festivalil "Poola klassika" neli preemiat : Nüganen sai lavastaja-, A. Sekula kunstnikupreemia ja lisaks kaks näitlejapreemiat - V. Bogdanasele ja S. Maciejewskile

  11. Birth of new folds and competing attractors in Elmo Bumpy Torus

    Energy Technology Data Exchange (ETDEWEB)

    Punjabi, A; Vahala, G

    1984-04-09

    The topology of equilibrium surfaces for the point model equations with neoclassical nonresonant ions in EBT is a complicated nongradient-dynamic version of the canonical cusp catastrophe. New folds emerge from degenerate equilibrium surfaces as the control vector (filling pressure, microwave power, ambipolar potential) is changed. Strong sensitivity to small changes in initial conditions of the state variables (electron/ion temperatures, plasma density) is found that can drastically alter the final equilibrium state when competing point attractors are present. 5 references, 3 figures.

  12. Magnetics transport aspects of EBTR reactors

    International Nuclear Information System (INIS)

    Bathke, C.G.

    1981-01-01

    The magnetic model developed for the ELMO Bumpy Torus Reactor (EBTR) study is described. A multiple-loop current simulation of toroidal-field (TF) and aspect-ratio-enhancement (ARE) coils is used to calculate the vacuum magnetic field. The bounce-averaged vertical drift velocity, v/sub y/, and poloidal drift frequency, Ω, are determined from the field topology. Upon performing the appropriate averages of v/sub y/ and Ω, the point-plasma toroidal curvature, R/sub T/, and magnetic curvature, R/sub c/, are obtained for use in modeling EBT transport. In addition, the fraction, f/sub α/, of alpha particles completing their first orbit within the plasma is calculated

  13. S3C: EBT Steady-State Shooting code description and user's guide

    International Nuclear Information System (INIS)

    Downum, W.B.

    1983-09-01

    The Oak Ridge National Laboratory (ORNL) one-dimensional (1-D) Steady-State Shooting code (S3C) for ELMO Bumpy Torus (EBT) plasmas is described. Benchmark calculations finding the steady-state density and electron and ion temperature profiles for a known neutral density profile and known external energy sources are carried out. Good agreement is obtained with results from the ORNL Radially Resolved Time Dependent 1-D Transport code for an EBT-Q type reactor. The program logic is described, along with the physics models in each code block and the variable names used. Sample input and output files are listed, along with the main code

  14. Üks PÖFF, tuhat maailma / Mathura

    Index Scriptorium Estoniae

    Mathura, pseud., 1973-

    2006-01-01

    Autorit enim köitnud filmidest PÖFFil: "Paani labürint" (režissöör Guillermo del Toro, Mehhiko-Hispaania, 2006), "Lillede org" (režissöör Pan Nalin, India-Prantsusmaa-Saksamaa-Jaapan, 2006), "Opera Jawa" (režissöör Garin Nugroho, Indoneesia-Austria, 2006), "Tsotsi" (režissöör Gavin Hood, LAV-Inglismaa, 2005), "Põuaperiood" (režissöör Mahamat-Saleh Haroun, Tšaad-Prantsusmaa-Belgia-Austria, 2006), "Meeletu" (režissöör Elmo Nüganen, Eesti, 2006), "Lahtikistud mees" (režissöör Aku Louhimies, Soome, 2006)

  15. SOME THEORETICAL MODELS EXPLAINING ADVERTISING EFFECTS

    Directory of Open Access Journals (Sweden)

    Vasilica Magdalena SOMEŞFĂLEAN

    2014-06-01

    Full Text Available Persuade clients is still the main focus of the companies, using a set of methods and techniques designed to influence their behavior, in order to obtain better results (profits over a longer period of time. Since the late nineteenth - early twentieth century, the american E.St.Elmo Lewis, considered a pioneer in advertising and sales, developed the first theory, AIDA model, later used by marketers and advertisers to develop a marketing communications strategy. Later studies have developed other models that are the main subject of this research, which explains how and why persuasive communication works, to understand why some approaches are effective and others are not.

  16. Quantitative Prediction of Power Loss for Damaged Photovoltaic Modules Using Electroluminescence

    Directory of Open Access Journals (Sweden)

    Timo Kropp

    2018-05-01

    Full Text Available Electroluminescence (EL is a powerful tool for the qualitative mapping of the electronic properties of solar modules, where electronic and electrical defects are easily detected. However, a direct quantitative prediction of electrical module performance purely based on electroluminescence images has yet to be accomplished. Our novel approach, called “EL power prediction of modules” (ELMO as presented here, used just two electroluminescence images to predict the electrical loss of mechanically damaged modules when compared to their original (data sheet power. First, using this method, two EL images taken at different excitation currents were converted into locally resolved (relative series resistance images. From the known, total applied voltage to the module, we were then able to calculate absolute series resistance values and the real distribution of voltages and currents. Then, we reconstructed the complete current/voltage curve of the damaged module. We experimentally validated and confirmed the simulation model via the characterization of a commercially available photovoltaic module containing 60 multicrystalline silicon cells, which were mechanically damaged by hail. Deviation between the directly measured and predicted current/voltage curve was less than 4.3% at the maximum power point. For multiple modules of the same type, the level of error dropped below 1% by calibrating the simulation. We approximated the ideality factor from a module with a known current/voltage curve and then expand the application to modules of the same type. In addition to yielding series resistance mapping, our new ELMO method was also capable of yielding parallel resistance mapping. We analyzed the electrical properties of a commercially available module, containing 72 monocrystalline high-efficiency back contact solar cells, which suffered from potential induced degradation. For this module, we predicted electrical performance with an accuracy of better

  17. Economic analysis of EBT reactor

    International Nuclear Information System (INIS)

    Woo, J.T.; Uckan, N.A.; Lidsky, L.M.

    1977-01-01

    In order to establish the economic potential of the Elmo Bumpy Torus (EBT) reactor, two independent system-costing models have been developed. Both models predict capital costs of approximately $400/kW(th). These relatively low costs reflect the simplicity of the EBTR design. In particular, the modular nature of the individual blanket-shield segments, the low costs ''accelerator style'' containment building, high beta, and steady-state operation lead to relatively low reactor costs. A detailed cost breakdown for subsystems is analyzed. High cost and high uncertainty subsystems are identified to direct further emphasis into those areas. The calculated capital costs for the EBT reactor are compared with those costs quoted for tokamak reactors

  18. Resonant ion transport in EBT

    International Nuclear Information System (INIS)

    Hastings, D.E.; Jaeger, E.F.; Hedrick, C.L.; Tolliver, J.S.

    1983-05-01

    We use a model for the ELMO Bumpy Torus as a bumpy cylinder with a toroidally induced vertical drift imposed on the plasma. With this model we obtain the neoclassical plasma-transport coefficients for ions in both the banana and plateau resonant regimes. The problem of solving the linearized bounce-averaged drift kinetic equation is formulated as a variational principle, which is shown to be valid for both the banana and plateau regimes. We use limiting forms of this principle to obtain a continuous collisionality approximation to the energy-dependent flux. We then use this approximation to obtain analytic formulae for the particle- and energy-diffusion coefficients. These are shown to give excellent agreement with numerical results

  19. Application of catastrophe theory to a point model for bumpy torus with neoclassical non-resonant electrons

    Energy Technology Data Exchange (ETDEWEB)

    Punjabi, A; Vahala, G [College of William and Mary, Williamsburg, VA (USA). Dept. of Physics

    1983-12-01

    The point model for the toroidal core plasma in the ELMO Bumpy Torus (with neoclassical non-resonant electrons) is examined in the light of catastrophe theory. Even though the point model equations do not constitute a gradient dynamic system, the equilibrium surfaces are similar to those of the canonical cusp catastrophe. The point model is then extended to incorporate ion cyclotron resonance heating. A detailed parametric study of the equilibria is presented. Further, the nonlinear time evolution of these equilibria is studied, and it is observed that the point model obeys the delay convention (and hence hysteresis) and shows catastrophes at the fold edges of the equilibrium surfaces. Tentative applications are made to experimental results.

  20. Eesti teatri aastaauhinnad 2006. aasta loomingu eest

    Index Scriptorium Estoniae

    2007-01-01

    Elmo Nüganen - lavastajaauhind, Ene-Liis Semper - kunstniku auhind, Hele Kõre - naisnäitleja auhind, Lembit Ulfsak - meesnäitleja auhind, Evelin Pang - naiskõrvalosa auhind, Margus Prangel - meeskõrvalosa auhind, Oleg Titov - draamalavastuse eriauhind, Helen Lokuta ja Lauri Sirp - muusikalavastuse auhind, Michiel Dijkema - muusikalavastuse eriauhind, Mare Tommingas - balletilavastuse auhind, ZUGA ühendatud tantsijad - tantsulavastuse auhind, Margus Mikomägi - kriitikaauhind, Tiit Sukk - Ants Lauteri näitlejaauhind, Ingomar Vihmar - Ants Lauteri lavastajaauhind, Rauno Elp - Georg Otsa auhind, Aare Toikka - Salme Reegi auhind, Reet Aus - Natalie Mei auhind, Anu Lamp - Priit Põldroosi auhind, Peeter Sauter - Aleksander Kurtna auhind, Artjom Maksakov ja Natalja Popenko - Kristallkingakese auhind, Enar Tarmo, Hendrik Kiisler ja Marika Tint - tehnilise töötaja auhind

  1. Eesti teatri aastaauhinnad 2006

    Index Scriptorium Estoniae

    2007-01-01

    Elmo Nüganen - lavastajaauhind, Ene-Liis Semper - kunstniku auhind, Hele Kõre - naisnäitleja auhind, Lembit Ulfsak - meesnäitleja auhind, Evelin Pang - naiskõrvalosa auhind, Margus Prangel - meeskõrvalosa auhind, Oleg Titov - draamalavastuse eriauhind, Helen Lokuta ja Lauri Sirp - muusikalavastuse auhind, Michiel Dijkema - muusikalavastuse eriauhind, Mare Tommingas - balletilavastuse auhind, ZUGA ühendatud tantsijad - tantsulavastuse auhind, Margus Mikomägi - kriitikaauhind, Tiit Sukk - Ants Lauteri näitlejaauhind, Ingomar Vihmar - Ants Lauteri lavastajaauhind, Rauno Elp - Georg Otsa auhind, Aare Toikka - Salme Reegi auhind, Reet Aus - Natalie Mei auhind, Anu Lamp - Priit Põldroosi auhind, Peeter Sauter - Aleksander Kurtna auhind, Artjom Maksakov ja Natalja Popenko - Kristallkingakese auhind, Enar Tarmo, Hendrik Kiisler ja Marika Tint - tehnilise töötaja auhind

  2. Quality-assurance approach for the Elmo Bumpy Torus Proof-of-Principal experiment

    International Nuclear Information System (INIS)

    Sticksel, F.M.

    1981-01-01

    Components, subsystems and systems will be subjected to inspection and test as necessary to ensure compliance to applicable specifications, Acceptance Test Procedures and/or customer requirements. Quality Assurance will inspect each component, subsystem and system for selected mechanical and electrical defects. In addition, Quality Assurance will either perform, or verify performance of, and analyze, or verify analysis of, all required field and laboratory tests. If hardware is modified, repaired or replaced after final testing, necessary re-inspection and retest must be performed. Insofar as possible the component, subsystem or system will be released as acceptable upon completion of these activities. When nonconformances are detected during the course of site surveillance activities, MDAC or Gilbert/Commonwealth will initiate a Nonconformance Record for review by MDAC Quality Assurance and Project Engineering personnel. These nonconformances will be identified and dispositioned per MDAC Standard Practices with the advice and concurrence of Gilbert/Commonwealth personnel, if deemed appropriate. MDAC Quality Assurance personnel will witness the pre-operational testing and review the test data

  3. Zavojevanije Moskvõ i polski projekt / Elmo Nüganen ; interv. Boris Tuch

    Index Scriptorium Estoniae

    Nüganen, Elmo, 1962-

    2004-01-01

    28. jaan. esietendus Moskvas Lenkomi teatris Tallinna Linnateatri peanäitejuhi E. Nüganeni lavastuses Y. Jamiaque'i "Härra Amilcar" (pealkirjaga "Kõik on makstud"). Lavastaja räägib oma tööst Moskva Lenkomi teatris ja eelseisvast W. Gombrowiczi näidendi "Laulatus" lavastamisest Poolas Toruni teatris

  4. Research program for plasma confinement and heating in ELMO bumpy torus devices

    International Nuclear Information System (INIS)

    Dandl, R.A.; Dory, R.A.; Eason, H.O.

    1975-06-01

    A sequence of experimental devices and related research activities which leads progressively toward an attractive full-scale reactor is described. The implementation of the steps in this sequence hinges on the development of microwave power sources, with high specific power levels, at millimeter wavelengths. Two proposed steps in this sequence are described. The first step proposed here, denoted EBT-S, requires increasing the EBT magnetic field to permit microwave heating at 18 and 28 GHz, as compared to the present 10.6 and 18-GHz configuration. A three-fold increase in plasma density, some increase in the temperatures, and an opportunity to test the validity of the transport models presently used to predict the plasma parameters are anticipated. This step will provide important operating experience with the 28-GHz power supplies, which are prototype tubes for millimeter sources at 120 GHz In the second step a new superconducting bumpy torus, EBT-II, would be fabricated to permit microwave heating at 90 and 120 GHz. This device would be designed to produce plasma densities and temperatures comparable to those of present-day tokamaks. This report reviews the experimental and theoretical research on EBT that has been carried out to date or formulated for the near future, and provides a status report as well as a research program plan. (U.S.)

  5. Comparative measurement of the neutral density and particle confinement time in EBT

    International Nuclear Information System (INIS)

    Glowienka, J.C.; Richards, R.K.

    1985-11-01

    The neutral density and particle confinement time in the ELMO Bumpy Torus-Scale Experiment (EBT-S) have been determined by two different techniques. These involve a spectroscopic measurement of molecular and atomic hydrogen emissions and a time-decay measurement of a fast-ion population using a diagnostic neutral beam. The results from both diagnostics exhibit identical trends for either estimate, although the absolute values differ by a factor of 2 to 3. The observed variations with fill gas pressure and microwave power from either technique are consistent with measurements of electron density and temperature. In this paper, the measurement techniques are discussed, and the results are compared in the context of consistency with independently observed plasma behavior. 6 refs., 7 figs

  6. Fusion research at ORNL

    International Nuclear Information System (INIS)

    1982-03-01

    The ORNL Fusion Program includes the experimental and theoretical study of two different classes of magnetic confinement schemes - systems with helical magnetic fields, such as the tokamak and stellarator, and the ELMO Bumpy Torus (EBT) class of toroidally linked mirror systems; the development of technologies, including superconducting magnets, neutral atomic beam and radio frequency (rf) heating systems, fueling systems, materials, and diagnostics; the development of databases for atomic physics and radiation effects; the assessment of the environmental impact of magnetic fusion; and the design of advanced demonstration fusion devices. The program involves wide collaboration, both within ORNL and with other institutions. The elements of this program are shown. This document illustrates the program's scope; and aims by reviewing recent progress

  7. The STM program at TRW

    International Nuclear Information System (INIS)

    Lazar, N.H.; Barter, J.; Boehmer, H.

    1984-01-01

    The objective of the STM is to evaluate the feasibility of confining a plasma stably in a symmetric mirror configuration by taking advantage of the use of diamagnetic plasma rings as in EBT to produce an MHD stable configuration. Experiments using both ECRH and ICRH in a five-cell, symmetric tandem-mirror facility STM are described. Streaming plasmas are produced, cw, in the end cells. Multiple frequency heating at electron cyclotron resonance efficiently generate the stabilizing ''ELMO'' rings. Ion cyclotron heating of ions in the stream results in ion energies in excess of 300eV with an energetic tail extending past 3keV. Monte Carlo simulations of the heating processes will be described. (author). 3 refs, 6 figs

  8. National RF Test Facility as a multipurpose development tool

    International Nuclear Information System (INIS)

    McManamy, T.J.; Becraft, W.R.; Berry, L.A.

    1983-01-01

    Additions and modifications to the National RF Test Facility design have been made that (1) focus its use for technology development for future large systems in the ion cyclotron range of frequencies (ICRF), (2) expand its applicability to technology development in the electron cyclotron range of frequencies (ECRF) at 60 GHz, (3) provide a facility for ELMO Bumpy Torus (EBT) 60-GHz ring physics studies, and (4) permit engineering studies of steady-state plasma systems, including superconducting magnet performance, vacuum vessel heat flux removal, and microwave protection. The facility will continue to function as a test bed for generic technology developments for ICRF and the lower hybrid range of frequencies (LHRF). The upgraded facility is also suitable for mirror halo physics experiments

  9. Wall effects on the absorption of electron cyclotron waves in an EBT plasma

    International Nuclear Information System (INIS)

    Uckan, T.

    1979-03-01

    The absorption of electron cyclotron waves propagating along an externally applied magnetic field in a uniform plasma surrounded by a cylindrical metallic cavity wall is studied. In the model, the cavity wall, the vacuum-plasma interface, and the effects of finite electron temperature are considered, and the dispersion relation for the wave propagation is derived. The results are then applied to the ELMO Bumpy Torus (EBT-I) plasma, and the propagation characteristics are computed. The wave absorption in the ordinary mode is found to be a result of the wall effects, which cannot be predicted with the infinite plasma theory. The loaded quality factor, Q/sub L/, is also estimated from the model to be about 12, which is in good agreement with the experimentally observed value

  10. Teatri aastaauhindade laureaadid 2007

    Index Scriptorium Estoniae

    2007-01-01

    Elmo Nüganen - lavastajaauhind, Ene-Liis Semper - kunstniku auhind, Hele Kõre - naisnäitleja auhind, Lembit Ulfsak - meesnäitleja auhind, Evelin Pang - naiskõrvalosa auhind, Margus Prangel - meeskõrvalosa auhind, Oleg Titov - draamalavastuse eriauhind, Helen Lokuta ja Lauri Sirp - muusikalavastuse auhind, Michiel Dijkema - muusikalavastuse eriauhind, Mare Tommingas - balletilavastuse auhind, ZUGA ühendatud tantsijad - tantsulavastuse auhind, Margus Mikomägi - kriitikaauhind, Tiit Sukk - Ants Lauteri näitlejaauhind, Ingomar Vihmar - Ants Lauteri lavastajaauhind, Rauno Elp - Georg Otsa auhind, Aare Toikka - Salme Reegi auhind, Reet Aus - Natalie Mei auhind, Anu Lamp - Priit Põldroosi auhind, Peeter Sauter - Aleksander Kurtna auhind, Artjom Maksakov ja Natalja Popenko - Kristallkingakese auhind, Enar Tarmo, Hendrik Kiisler ja Marika Tint - tehnilise töötaja auhind. Ka Kuressaares toimunud teatripeost

  11. Teatri aastaauhindade laureaadid 2007

    Index Scriptorium Estoniae

    2007-01-01

    Nimekiri teatri aastaauhinna laureaatidest sõna-, muusika-, balleti-, tantsulavastuste, teatri tehnilise töötaja auhinna kategoorias ja aasta kriitikaauhind. Elmo Nüganen - lavastajaauhind, Ene-Liis Semper - kunstniku auhind, Hele Kõre - naisnäitleja auhind, Lembit Ulfsak - meesnäitleja auhind, Evelin Pang - naiskõrvalosa auhind, Margus Prangel - meeskõrvalosa auhind, Oleg Titov - draamalavastuse eriauhind, Helen Lokuta ja Lauri Sirp - muusikalavastuse auhind, Michiel Dijkema - muusikalavastuse eriauhind, Mare Tommingas - balletilavastuse auhind, ZUGA ühendatud tantsijad - tantsulavastuse auhind, Margus Mikomägi - kriitikaauhind, Tiit Sukk - Ants Lauteri näitlejaauhind, Ingomar Vihmar - Ants Lauteri lavastajaauhind, Rauno Elp - Georg Otsa auhind, Aare Toikka - Salme Reegi auhind, Reet Aus - Natalie Mei auhind, Anu Lamp - Priit Põldroosi auhind, Peeter Sauter - Aleksander Kurtna auhind, Artjom Maksakov ja Natalja Popenko - Kristallkingakese auhind

  12. Engineering design of a toroidal divertor for the EBT-S fusion device. Final report, Phase II. EBT-S divertor project

    International Nuclear Information System (INIS)

    Mai, L.P.; Malick, F.S.

    1981-01-01

    The mechanical, structural, thermal, electrical, and vacuum design of a magnetic toroidal divertor system for the Elmo Bumpy Torus (EBT-S) is presented. The EBT-S is a toroidal magnetic fusion device located at the ORNL that operates under steady state conditions. The engineering of the divertor was performed during the second of three phases of a program aimed at the selection, design, fabrication, and installation of a magnetic divertor for EBT-S. The magnetic analysis of the toroidal divertor was performed during Phase I of the program and has been reported in a separate document. In addition to the details of the divertor design, the modest modifications that are required to the EBT-S device and facility to accommodate the divertor system are presented

  13. Plasma Theory Division

    International Nuclear Information System (INIS)

    Callen, J.D.; Dory, R.A.; Aghevli, R.

    1977-01-01

    The progress during the past year is organized by group efforts and divided into five major areas. The basic tokamak areas and the sections in which their work is summarized are: magnetohydrodynamic (MHD) theory, kinetic theory, and transport simulation. The ELMO Bumpy Torus (EBT) theory work has its own research projects on MHD theory, kinetic theory, and transport simulation. In the plasma engineering area, relevant research work is further developed and synthesized into models that are used in the design of advanced fusion systems--The Next Step (TNS), demonstration fusion reactor (Demo), EBT ignition test, etc. Specific plasma engineering projects on providing the TNS physics basis and the development of the EBT reactor study are discussed. The computing support activities during the past year are summarized

  14. EBTR design-point selection

    International Nuclear Information System (INIS)

    Krakowski, R.A.; Bathke, C.G.

    1981-01-01

    The procedure used to select the design point for the ELMO Bumpy Torus Reactor (EBTR) study is described. The models used in each phase of the selection process are described, with an emphasis placed on the parametric design curves produced by each model. The tradeoffs related to burn physics, stability/equilibrium, electron-ring physics, and magnetics design are discussed. The resulting design point indicates a plasma with a 35-m major radius and a 1-m minor radium operating at an average core-plasma beta of 0.17, which at approx. 30 keV produces an average neutron wall loading of 1.4 MW/m 2 while maintaining key magnet (< 10 T) and total power (less than or equal to 4000 MWt) constraints

  15. Elmo Nüganeni lavastus "Laulatus" pälvis mitu autasu mainekal festivalil Poolas

    Index Scriptorium Estoniae

    2005-01-01

    E. Nüganeni Poolas, Toruni teatris valminud lavastus - W. Gombrowiczi "Laulatus"- pälvis Opole festivalil "Poola klassika" neli preemiat : Nüganen sai lavastaja-, A. Sekula kunstnikupreemia ja lisaks kaks näitlejapreemiat - V. Bogdanasele ja S. Maciejewskile

  16. Verivärskeid elamusi igale maitsele / Marianne Kõrver

    Index Scriptorium Estoniae

    Kõrver, Marianne, 1980-

    2007-01-01

    Ülevaade 10. PÖFFi võistlusprogrammist. PÖFFi filme: "Meeletu" (rezh. Elmo Nüganen), "TumeSininePeaaeguMust" (rezh. Daniel Sanchez Arevalo), "Taksitermia" (rezh. György Palfi), "Eravaldus" (rezh. Joachim Lafosse), "Lahtikistud mees" (rezh. Aku Louhimies), "Rõhkkonnad" (rezh. Nuri Bilge Ceylan), "Reekviem" (rezh. Hans-Christian Schmid), "Väikesed punased lilled" (rezh. Zhang Yuan), "Sündroomid ja sajand" (režissöör Apichatpong Weerasethakul), "Mängides ohvrit" (rezh. Kirill Serebrennikov), "Et taevasse pääseda, tuleb kõigepealt surra" (rezh. Djamshed Usmonov), "Pojad" (rezh. Erik Strand Richter), "Maximo Oliverose õitseaeg" (rezh. Auraeus Solito), "Kelner" (rezh. Alex van Warmerdam), "Tagasinõudja" (rezh. Slawomir Fabick), "Mehed tööl" (rezh. Mani Haghighi), "4,6 miljardit aastat armastust" (rezh. Takashi Miike), "Sina oled mina" (rezh. Kristijonas Vildziunas)

  17. Kinetic stability analyses in a bumpy cylinder

    International Nuclear Information System (INIS)

    Dominguez, R.R.; Berk, H.L.

    1981-01-01

    Recent interest in the ELMO Bumpy Torus (EBT) has prompted a number of stability analyses of both the hot electron rings and the toroidal plasma. Typically these works employ the local approximation, neglecting radial eigenmode structure and ballooning effects to perform the stability analysis. In the present work we develop a fully kinetic formalism for performing nonlocal stability analyses in a bumpy cylinder. We show that the Vlasov-Maxwell integral equations (with one ignorable coordinate) are self-adjoint and hence amenable to analysis using numerical techniques developed for self-adjoint systems of equations. The representation we obtain for the kernel of the Vlasov-Maxwell equations is a differential operator of arbitrarily high order. This form leads to a manifestly self-adjoint system of differential equations for long wavelength modes

  18. Reactor assessments of advanced bumpy torus configurations

    International Nuclear Information System (INIS)

    Uckan, N.A.; Owen, L.W.; Spong, D.A.; Miller, R.L.; Ard, W.B.; Pipkins, J.F.; Schmitt, R.J.

    1984-02-01

    Recently, several innovative approaches were introduced for enhancing the performance of the basic ELMO Bumpy Torus (EBT) concept and for improving its reactor potential. These include planar racetrack and square geometries, Andreoletti coil systems, and bumpy torus-stellarator hybrids (which include twisted racetrack and helical axis stellarator - snakey torus). Preliminary evaluations of reactor implications of each approach have been carried out based on magnetics (vacuum) calculations, transport and scaling relationships, and stability properties deduced from provisional configurations that implement the approach but are not necessarily optimized. Further optimization is needed in all cases to evaluate the full potential of each approach. Results of these studies indicate favorable reactor projections with a significant reduction in reactor physical size as compared to conventional EBT reactor designs carried out in the past

  19. High power electron cyclotron heating in ISX and ORMAK Upgrade at ORNL

    International Nuclear Information System (INIS)

    England, A.C.; Eldridge, O.C.; Marcus, F.B.; Sprott, J.C.; Namkung, W.; Wilgen, J.B.

    1976-05-01

    A phased program of plasma heating at the electron cyclotron frequency is proposed for the Oak Ridge tokamaks ISX and ORMAK Upgrade. The past history of the program of electron cyclotron heating (ECH) at ORNL on mirrors and in the ELMO Bumpy Torus has been successful. Future technological developments in the production of high power high frequency microwave tubes look promising at this time. The physics of wave propagation and particle heating are fairly well understood and indicate the viability of this technique. Studies on breakdown and on runaway electron reduction will provide useful information for larger machines. Recent experiments in the USSR on small tokamaks have shown that ECH is a viable heating technique. Providing that the microwave tubes become available, the engineering considerations suggest that the technique is practical and workable, based on present day technology

  20. Extreme ultraviolet and soft x-ray diagnostics of high-temperature plasmas. Annual progress report, June 1, 1977--May 31, 1978

    International Nuclear Information System (INIS)

    Moos, H.W.; Armstrong, L. Jr.; Fastie, W.G.

    1978-01-01

    Spatial scans of Alcator Tokamak have led to a more direct determination of the oxygen and nitrogen concentrations. These scans have also shown that grad B and curvature drifts are significant transport mechanisms in this device. Spatial scans of Elmo Bumpy Torus from both the top and the side have produced two dimensional plots of the impurity concentrations. Preliminary results from 2XIIB show that oxygen is the dominant impurity; nitrogen, carbon, and titanium are also present. The Spatial Imaging Detector System is discussed; construction is complete and it is being prepared for installation on a plasma machine. EUV photometric calibration techiques at this laboratory are described. The accuracy and stability of this calibration is discussed. Theoretical calculations of relativistic transition rates and energies have continued, and studies of electron-impact ionization and excitation cross sections have begun

  1. The language and culture of delay.

    Science.gov (United States)

    Sakai, Christina; Shetgiri, Rashmi; Flores, Glenn; Caronna, Elizabeth; Khandekar, Aasma; Augustyn, Marilyn

    2010-04-01

    Hindi. His parents describe him as using "odd language" in that he will often mix up his pronouns. Satish is in an English-speaking preschool. His preschool teachers report concerns that he seems to "withdraw into his own world," and does not interact well with the other children. They also report attentional problems and poor eye contact.In the office, Satish makes good eye contact with the examiner and his parents. He looks to his parents for approval when completing a task requested of him. He seems to like an Elmo toy that is in the room but holds it and looks at it closely rather than pretend to do anything with it. You ask him to feed Elmo, and he says, "Feed Elmo." Because it is not clear whether he understands the verbal cues given to him, his parents repeat English directions to him in Hindi several times. He eventually complies but then leaves his chair to explore the room. His parents continue to translate your questions to him with variable results. He becomes increasingly difficult to engage, despite repeated attempts, in both English and Hindi, to attract his attention. Where do you go from here?

  2. Formation of stable, high-beta, relativistic-electron plasmas using electron cyclotron heating

    International Nuclear Information System (INIS)

    Guest, G.E.; Miller, R.L.

    1988-01-01

    A one-dimensional, steady-state, relativistic Fokker-Planck model of electron cyclotron heating (ECH) is used to analyse the heating kinetics underlying the formation of the two-component hot-electron plasmas characteristic of ECH in magnetic mirror configurations. The model is first applied to the well diagnosed plasmas obtained in SM-1 and is then used to simulate the effective generation of relativistic electrons by upper off-resonant heating (UORH), as demonstrated empirically in ELMO. The characteristics of unstable whistler modes and cyclotron maser modes are then determined for two-component hot-electron plasmas sustained by UORH. Cyclotron maser modes are shown to be strongly suppressed by the colder background electron species, while the growth rates of whistler modes are reduced by relativistic effects to levels that may render them unobservable, provided the hot-electron pressure anisotropy is below an energy dependent threshold. (author). 29 refs, 10 figs, 1 tab

  3. Effect of beta limits on reactor performance in EBT

    International Nuclear Information System (INIS)

    Uckan, N.A.; Spong, D.A.; Nelson, D.B.

    1981-01-01

    Because of uncertainties in extrapolating results of simplified models to a reactor plasma, the parameters that influence the beta limits cannot be determined accurately at the present time. Also, the reasonable changes within the models and/or assumptions are seen to affect the core beta limits by almost an order of magnitde. Hence, at the present, these limits cannot be used as a rigid (and reliable) requirement for ELMO Bumpy Torus (EBT) reactor engineering considerations. However, sensitivity studies can be carried out to determine the boundaries of the operating regime and to demonstrate the effects of various modes, assumptions, and models on reactor performance (Q value). First, the modes believed to limit the core β and ring plasma performance are discussed, and the simplifications and/or assumptions involved in deriving these limits are highlighted. Then, the implications of these limits for a reactor are given

  4. Fusion energy division annual progress report, period ending December 31, 1980

    Energy Technology Data Exchange (ETDEWEB)

    1981-11-01

    The ORNL Program encompasses most aspects of magnetic fusion research including research on two magnetic confinement programs (tokamaks and ELMO bumpy tori); the development of the essential technologies for plasma heating, fueling, superconducting magnets, and materials; the development of diagnostics; the development of atomic physics and radiation effect data bases; the assessment of the environmental impact of magnetic fusion; the physics and engineering of present-generation devices; and the design of future devices. The integration of all of these activities into one program is a major factor in the success of each activity. An excellent example of this integration is the extremely successful application of neutral injection heating systems developed at ORNL to tokamaks both in the Fusion Energy Division and at Princeton Plasma Physics Laboratory (PPPL). The goal of the ORNL Fusion Program is to maintain this balance between plasma confinement, technology, and engineering activities.

  5. Fusion energy division annual progress report, period ending December 31, 1980

    International Nuclear Information System (INIS)

    1981-11-01

    The ORNL Program encompasses most aspects of magnetic fusion research including research on two magnetic confinement programs (tokamaks and ELMO bumpy tori); the development of the essential technologies for plasma heating, fueling, superconducting magnets, and materials; the development of diagnostics; the development of atomic physics and radiation effect data bases; the assessment of the environmental impact of magnetic fusion; the physics and engineering of present-generation devices; and the design of future devices. The integration of all of these activities into one program is a major factor in the success of each activity. An excellent example of this integration is the extremely successful application of neutral injection heating systems developed at ORNL to tokamaks both in the Fusion Energy Division and at Princeton Plasma Physics Laboratory (PPPL). The goal of the ORNL Fusion Program is to maintain this balance between plasma confinement, technology, and engineering activities

  6. Elmo Bumpy Torus proof of principle. Phase II - title 1 report. Volume I. Device summary

    International Nuclear Information System (INIS)

    Haas, D.W.

    1982-02-01

    This document presents a summary of the EBT-P Preliminary Design (Title I) effort. The work was performed, under the direction of ORNL, for the Department of Energy by MDAC-St. Louis. Major subcontractors assisting MDAC included General Dynamics for the magnet system, Gilbert Associates for the device utilities and facility architecture and engineering, and Lockheed - Oak Ridge for engineering support services. The Title I period of performance was from 1 October 1980 to 1 March 1982

  7. Elmo Bumpy Torus proof of principle, Phase II: Title 1 report. Volume VII. Cryogenic system

    International Nuclear Information System (INIS)

    Poteat, T.J.

    1982-01-01

    This document, Volume VII EBT-P Cryogenic System Title I Design Report, describes the system that resulted from the Title I Preliminary Design effort. It is a self-contained document that can be read apart from the other Volumes comprising the EBT-P Title I Report. This document is a contract deliverable item and provides the detail necessary to support the Cryogenic System design contained in the EBT-P Baseline Design Data Book

  8. Elmo Bumpy Torus proof of principle, Phase II: Title 1 report. Volume IX. Support structure

    International Nuclear Information System (INIS)

    Conlee, J.L.

    1982-01-01

    The EBT-P support structure provides structural support for the 36 mirror coil magnets, magnet protection system, the toroidal vessel, and much of the device ancillary equipment. The structure is comprised of a primary support and a superstructure. The primary support is a reinforced concrete ring located directly inboard of the torus and is supported by nine columns. The toroidal vessel and the mirror coil magnets are cantilevered from the ring with the centerline of the torus located eight feet above the floor. The superstructure is an aluminum truss structure that rests on the concrete ring. The superstructure provides support for the device ancillary equipment. Engineering drawings of the support structure are given

  9. Elmo Bumpy Torus proof of principle, Phase II: Title 1 report. Volume II. Toroidal vessel

    International Nuclear Information System (INIS)

    1982-01-01

    The Toroidal Vessel provides the vacuum enclosure for containing the high temperature steady state plasma. In addition, the Toroidal Vessel must provide several viewing ports for plasma diagnostics, vacuum pumping ports for both high vacuum and roughing vacuum, feed-through ports for ECRH waveguides, limiter feed throughs for cooling and supporting the limiters, and ports for ion gages. The vessel must operate in an intense environment comprised of x-rays, microwaves, magnetic fields and plasma heat loads as well as the atmosphere pressure and gravity loads and the internal thermal stress loads due to heating and cooling of the torus. A key issue addressed was the choice of vacuum vessel seal and wall materials. In addition, during the course of the study, ORNL requested that horsecollar diagnostic ports be incorporated in the design. A comprehensive trade study was performed considering the vessel material issues in concert with the impact of the horsecollar port design. A change in baseline from an aluminum vessel with elastomer seals and circular diagnostic ports to austenitic stainless steel vessel with metal seals and horsecollar ports was agreed upon by both MDAC and ORNL towards the end of Title I

  10. Elmo Bumpy Torus proof of principle, Phase II: Title 1 report. Volume VIII. Device utilities

    Energy Technology Data Exchange (ETDEWEB)

    Erickson, D.T.

    1982-02-26

    This report describes the activities conducted during the Preliminary Design Period for the Device Utilities Systems. All GAI preliminary specifications, drawings, and reports (listed in Section 4.0) have been transmitted to ORNL for review and approval. Device Utility Systems Descriptions are also presented in Section 4.0. The GAI Device Enclosure Gamma Radiation Analysis is presented in Appendix B. Pending design criteria revisions are described in Section 6.0. A type B Change Notice Request (CNR) has been transmitted to GAI. The Type B CNR authorizes cost and schedule assessment for each revision identified. Formal Proposed Design Changes (PDC's) will be provided to ORNL when this data is available.

  11. Elmo Bumpy Torus proof of principle, Phase II: Title 1 report. Volume VIII. Device utilities

    International Nuclear Information System (INIS)

    Erickson, D.T.

    1982-01-01

    This report describes the activities conducted during the Preliminary Design Period for the Device Utilities Systems. All GAI preliminary specifications, drawings, and reports (listed in Section 4.0) have been transmitted to ORNL for review and approval. Device Utility Systems Descriptions are also presented in Section 4.0. The GAI Device Enclosure Gamma Radiation Analysis is presented in Appendix B. Pending design criteria revisions are described in Section 6.0. A type B Change Notice Request (CNR) has been transmitted to GAI. The Type B CNR authorizes cost and schedule assessment for each revision identified. Formal Proposed Design Changes (PDC's) will be provided to ORNL when this data is available

  12. EBT-S 28-GHz, 200-kW, CW, mixed-mode, quasi-optical plasma heating system

    International Nuclear Information System (INIS)

    White, T.L.; Kimrey, H.D.; Bigelow, T.S.; Bates, D.D.; Eason, H.O.

    1984-07-01

    The ELMO Bumpy Torus-Scale (EBT-S) 28-GHz, 200-kW, cw, plasma heating system consists of a gyrotron oscillator, an oversized waveguide two-bend transmission system, and a quasi-optical mixed-mode microwave distribution manifold that feeds microwave power to the 24 plasma loads of the EBT-S fusion experiment. Balancing power to the 24 loads of the EBT-S fusion experiment. Balancing power to the 24 loads was achieved by adjusting the areas at 24 coupling irises. System performance is easily measured using system calorimetry. The distribution manifold mixed-mode power transmission, reflection, and loss coefficients are 89%, 6%, and 5%, respectively. The overall system efficiency (plasma power/gyrotron power) is 80%, but with some modifications to the distribution manifold we believe the ultimate efficiency can approach 90%. The system reliability is outstanding with a world's record 1 x 10 5 kW h of 28-GHz energy delivered to the EBT-S device with well over 1 x 10 3 operating hours

  13. Molecular characterization of feline infectious peritonitis virus strain DF-2 and studies of the role of ORF3abc in viral cell tropism.

    Science.gov (United States)

    Bálint, Ádám; Farsang, Attila; Zádori, Zoltán; Hornyák, Ákos; Dencso, László; Almazán, Fernando; Enjuanes, Luis; Belák, Sándor

    2012-06-01

    The full-length genome of the highly lethal feline infectious peritonitis virus (FIPV) strain DF-2 was sequenced and cloned into a bacterial artificial chromosome (BAC) to study the role of ORF3abc in the FIPV-feline enteric coronavirus (FECV) transition. The reverse genetic system allowed the replacement of the truncated ORF3abc of the original FIPV DF-2 genome with the intact ORF3abc of the canine coronavirus (CCoV) reference strain Elmo/02. The in vitro replication kinetics of these two viruses was studied in CrFK and FCWF-4 cell lines, as well as in feline peripheral blood monocytes. Both viruses showed similar replication kinetics in established cell lines. However, the strain with a full-length ORF3 showed markedly lower replication of more than 2 log(10) titers in feline peripheral blood monocytes. Our results suggest that the truncated ORF3abc plays an important role in the efficient macrophage/monocyte tropism of type II FIPV.

  14. Toroidal plasmoid generation via extreme hydrodynamic shear.

    Science.gov (United States)

    Gharib, Morteza; Mendoza, Sean; Rosenfeld, Moshe; Beizai, Masoud; Alves Pereira, Francisco J

    2017-11-28

    Saint Elmo's fire and lightning are two known forms of naturally occurring atmospheric pressure plasmas. As a technology, nonthermal plasmas are induced from artificially created electromagnetic or electrostatic fields. Here we report the observation of arguably a unique case of a naturally formed such plasma, created in air at room temperature without external electromagnetic action, by impinging a high-speed microjet of deionized water on a dielectric solid surface. We demonstrate that tribo-electrification from extreme and focused hydrodynamic shear is the driving mechanism for the generation of energetic free electrons. Air ionization results in a plasma that, unlike the general family, is topologically well defined in the form of a coherent toroidal structure. Possibly confined through its self-induced electromagnetic field, this plasmoid is shown to emit strong luminescence and discrete-frequency radio waves. Our experimental study suggests the discovery of a unique platform to support experimentation in low-temperature plasma science. Copyright © 2017 the Author(s). Published by PNAS.

  15. EBT-P gamma-ray-shielding analysis

    International Nuclear Information System (INIS)

    Gohar, Y.

    1983-01-01

    First, a one-dimensional scoping study was performed for the gamma-ray shield of the ELMO Bumpy Torus proof-of-principle device to define appropriate shielding material and determine the required shielding thickness. The dose-equivalent results are analyzed as a function of the radiation-shield thickness for different shielding options. A sensitivity analysis for the pessimistic case is given. The recommended shielding option based on the performance and cost is discussed. Next, a three-dimensional scoping study for the coil shield was performed for four different shielding options to define the heat load for each component and check the compliance with the design criterion of 10 watts maximum heat load per coil from the gamma-ray sources. Also, a detailed biological-dose survey was performed which included: (a) the dose equivalent inside and outside the building, (b) the dose equivalent from the two mazes of the building, and (c) the skyshine contribution to the dose equivalent

  16. Office of Fusion Energy recommendations on the Elmo Bumpy Torus proof-of-principle experiment site selection

    International Nuclear Information System (INIS)

    1980-01-01

    This report provies background information and rationale for the procedures used and decisions made up to this point. A brief history and technical description of the EBT concept are given. The OFE recommendations as to siting are included

  17. Bottoms up design of the Elmo Bumpy Torus - proof of principal (EBT-P) fusion research facility

    International Nuclear Information System (INIS)

    Erickson, D.T.

    1981-01-01

    The McDonnell Douglas Astronautics Company, under subcontract to the Union Carbide Corporation Nuclear Division at the DOE Oak Ridge National Laboratory has committed to furnish the EBT-P research facility. Gilbert Associates, Inc. of Reading, Pennysylvania, as the Architect and Engineering subcontractor has been selected for design and construction of this facility. The bottoms up effort to provide the EBT-P facility is now alive and well, with the property purchased, dedication ceremonies conducted, the Preliminary Design effort completed and detail design currently active

  18. Status of the theoretical study of microwave heating in EBT

    International Nuclear Information System (INIS)

    Batchelor, D.B.

    1978-09-01

    The basic strategy of the theoretical study of microwave heating in the ELMO Bumpy Torus (EBT) is outlined and the current status of the various aspects of the study is described. There are four broad areas which are being investigated: (1) heating and wave damping mechanisms, (2) the geometrical optics of microwave propagation in EBT, (3) reflection and mode conversion effects at regions such as cutoff and resonances where the geometrical optics approximation breaks down, and (4) nonlinear effects such as ponderamotive effects and parametric decay. Details are given of the geometrical optics code which has been developed to do ray tracing in arbitrary three dimensional (3-D) plasma equilibria. Examples are given for plasma parameters characteristic of EBT-I and EBT-II. Details are also given of the stochastic heating model currently in use with the 1-D transport code and of the linear wave damping model used in the ray tracing code. The most pressing problems of physics yet to be addressed and the directions for future work are indicated

  19. Radio frequency heating of fusion plasms

    International Nuclear Information System (INIS)

    Swanson, D.G.

    1983-01-01

    The electron cyclotron range of frequencies has been used successfully for plasma heating perhaps longer than any other RF plasma heating scheme and is generally well understood. The problem has always been that the strong magnetic field required for fusion devices puts the electron cyclotron frequency so high that it is at or above the high power technology limit. The development of high power gyrotrons (> 200 kW) in recent years with steadily rising frequency limits, however, has brought about a renaissance of interest in ECRH as relativistic electron energies well in excess of those required for fusion have been obtained. The relativistic electron ring stabilization of the Elmo Bumpy Torus (EBT), which was achieved with ECRF, only at one point made the EBT the most promising new fusion concept of the last decade. The results also made clear that the physical understanding of the heating processes in this frequency range, so long neglected because of the technology limitation, are not fully understood so that more basic physics is necessary before ECRF can reach the potential that technology now seems to allow

  20. Design for the National RF Test Facility at ORNL

    International Nuclear Information System (INIS)

    Gardner, W.L.; Hoffman, D.J.; Becraft, W.R.

    1983-01-01

    Conceptual and preliminary engineering design for the National RF Test Facility at Oak Ridge National Laboratory (ORNL) has been completed. The facility will comprise a single mirror configuration embodying two superconducting development coils from the ELMO Bumpy Torus Proof-of-Principle (EBT-P) program on either side of a cavity designed for full-scale antenna testing. The coils are capable of generating a 1.2-T field at the axial midpoint between the coils separated by 1.0 m. The vacuum vessel will be a stainless steel, water-cooled structure having an 85-cm-radius central cavity. The facility will have the use of a number of continuous wave (cw), radio-frequency (rf) sources at levels including 600 kW at 80 MHz and 100 kW at 28 GHz. Several plasma sources will provide a wide range of plasma environments, including densities as high as approx. 5 x 10 13 cm -3 and temperatures on the order of approx. 10 eV. Furthermore, a wide range of diagnostics will be available to the experimenter for accurate appraisal of rf testing

  1. Superconducting magnets for toroidal fusion reactors

    International Nuclear Information System (INIS)

    Haubenreich, P.N.

    1980-01-01

    Fusion reactors will soon be employing superconducting magnets to confine plasma in which deuterium and tritium (D-T) are fused to produce usable energy. At present there is one small confinement experiment with superconducting toroidal field (TF) coils: Tokamak 7 (T-7), in the USSR, which operates at 4 T. By 1983, six different 2.5 x 3.5-m D-shaped coils from six manufacturers in four countries will be assembled in a toroidal array in the Large Coil Test Facility (LCTF) at Oak Ridge National Laboratory (ORNL) for testing at fields up to 8 T. Soon afterwards ELMO Bumpy Torus (EBT-P) will begin operation at Oak Ridge with superconducting TF coils. At the same time there will be tokamaks with superconducting TF coils 2 to 3 m in diameter in the USSR and France. Toroidal field strength in these machines will range from 6 to 9 T. NbTi and Nb 3 Sn, bath cooling and forced flow, cryostable and metastable - various designs are being tried in this period when this new application of superconductivity is growing and maturing

  2. Fusion Energy Division annual progress report period ending December 31, 1983

    Energy Technology Data Exchange (ETDEWEB)

    1984-09-01

    The Fusion Program carries out work in a number of areas: (1) experimental and theoretical research on two magnetic confinement concepts - the ELMO Bumpy Torus (EBT) and the tokamak, (2) theoretical and engineering studies on a third concept - the stellarator, (3) engineering and physics of present-generation fusion devices, (4) development and testing of diagnostic tools and techniques, (5) development and testing of materials for fusion devices, (6) development and testing of the essential technologies for heating and fueling fusion plasmas, (7) development and testing of the superconducting magnets that will be needed to confine these plasmas, (8) design of future devices, (9) assessment of the environmental impact of fusion energy, and (10) assembly and distribution to the fusion community of data bases on atomic physics and radiation effects. The interactions between these activities and their integration into a unified program are major factors in the success of the individual activities, and the ORNL Fusion Program strives to maintain a balance among these activities that will lead to continued growth.

  3. Fusion Energy Division annual progress report period ending December 31, 1983

    International Nuclear Information System (INIS)

    1984-09-01

    The Fusion Program carries out work in a number of areas: (1) experimental and theoretical research on two magnetic confinement concepts - the ELMO Bumpy Torus (EBT) and the tokamak, (2) theoretical and engineering studies on a third concept - the stellarator, (3) engineering and physics of present-generation fusion devices, (4) development and testing of diagnostic tools and techniques, (5) development and testing of materials for fusion devices, (6) development and testing of the essential technologies for heating and fueling fusion plasmas, (7) development and testing of the superconducting magnets that will be needed to confine these plasmas, (8) design of future devices, (9) assessment of the environmental impact of fusion energy, and (10) assembly and distribution to the fusion community of data bases on atomic physics and radiation effects. The interactions between these activities and their integration into a unified program are major factors in the success of the individual activities, and the ORNL Fusion Program strives to maintain a balance among these activities that will lead to continued growth

  4. Extreme ultraviolet and soft x-ray diagnostics of high-temperature plasmas. Annual progress report, June 1, 1976--May 31, 1977

    International Nuclear Information System (INIS)

    Moos, H.W.; Armstrong, L. Jr.; Fastie, W.G.

    1977-01-01

    The results of the research program at this laboratory from mid February 1976 until January 31, 1977, are described. The four major research areas of the program: diagnostic studies of magnetically confined high temperature plasmas, supporting laboratory studies, theoretical studies of highly ionized atoms, and instrument development are discussed. Spatially resolved ultraviolet measurements on Elmo Bumpy Torus have determined impurity confinement times. The measured oxygen densities and fluxes are being determined at Alcator; the spectroscopic studies show that hydrogen discharges in this tokamak have an effective Z close to one. A laboratory study of the Penning discharge between 100 and 300 A shows that it is a bright source for evaluation of EUV diagnostic instrumentation. Design of a multispatial element spectrometer system is complete and construction has begun. A spectrophotometer compatible with both types of facilities is available for absolute intensity calibration transfer from the NBS SURF II facility to ERDA plasma facilities. Computer programs needed for relativistic calculation of transition probabilities and wavelengths have been completed and applied to calculations in the Li, Be, Ar, and K isoelectronic sequences

  5. Mixed-mode distribution systems for high average power electron cyclotron heating

    International Nuclear Information System (INIS)

    White, T.L.; Kimrey, H.D.; Bigelow, T.S.

    1984-01-01

    The ELMO Bumpy Torus-Scale (EBT-S) experiment consists of 24 simple magnetic mirrors joined end-to-end to form a torus of closed magnetic field lines. In this paper, we first describe an 80% efficient mixed-mode unpolarized heating system which couples 28-GHz microwave power to the midplane of the 24 EBT-S cavities. The system consists of two radiused bends feeding a quasi-optical mixed-mode toroidal distribution manifold. Balancing power to the 24 cavities is determined by detailed computer ray tracing. A second 28-GHz electron cyclotron heating (ECH) system using a polarized grid high field launcher is described. The launcher penetrates the fundamental ECH resonant surface without a vacuum window with no observable breakdown up to 1 kW/cm 2 (source limited) with 24 kW delivered to the plasma. This system uses the same mixed-mode output as the first system but polarizes the launched power by using a grid of WR42 apertures. The efficiency of this system is 32%, but can be improved by feeding multiple launchers from a separate distribution manifold

  6. Equilibrium: two-dimensional configurations

    International Nuclear Information System (INIS)

    Anon.

    1987-01-01

    In Chapter 6, the problem of toroidal force balance is addressed in the simplest, nontrivial two-dimensional geometry, that of an axisymmetric torus. A derivation is presented of the Grad-Shafranov equation, the basic equation describing axisymmetric toroidal equilibrium. The solutions to equations provide a complete description of ideal MHD equilibria: radial pressure balance, toroidal force balance, equilibrium Beta limits, rotational transform, shear, magnetic wall, etc. A wide number of configurations are accurately modeled by the Grad-Shafranov equation. Among them are all types of tokamaks, the spheromak, the reversed field pinch, and toroidal multipoles. An important aspect of the analysis is the use of asymptotic expansions, with an inverse aspect ratio serving as the expansion parameter. In addition, an equation similar to the Grad-Shafranov equation, but for helically symmetric equilibria, is presented. This equation represents the leading-order description low-Beta and high-Beta stellarators, heliacs, and the Elmo bumpy torus. The solutions all correspond to infinitely long straight helices. Bending such a configuration into a torus requires a full three-dimensional calculation and is discussed in Chapter 7

  7. Aja sõltlased - kes kus : Elmo Nüganeni 'Pianoola ehk Mehhaaniline klaver' Tallinna Linnateatris / Lauri Kärk

    Index Scriptorium Estoniae

    Kärk, Lauri, 1954-

    1996-01-01

    Anton Tšehhovi - Aleksandr Adabashjani - Nikita Mihhalkovi 'Pianoola ehk Mehhaaniline klaver' Tallinna Linnateatris, lav. E. Nüganen. Võrdlus N. Mihhalkovi filmiga 'Lõpetamata pala pianoolale' (1977)

  8. What Can Librarians Learn from Elmo, Sid, and Dora? Applying the Principles of Educational Television to Storytime

    Science.gov (United States)

    Cahill, Maria; Bigheart, Jennifer

    2016-01-01

    Parents and caregivers can maximize children's engagement with educational television programming by co-viewing and discussing concepts and issues during and following episodes, and parents and caregivers can poach ideas and processes from these programs and apply them to their own interactions with children. School librarians might also consider…

  9. Research support for plasma diagnostics on Elmo Bumpy Torus: investigation of diamagnetic diagnostics for the electron rings

    International Nuclear Information System (INIS)

    Carpenter, K.H.

    1981-02-01

    Diamagnetic diagnostics for the EBT electron rings are fundamental to the experiment. The diamagnetic flux pickup loops on each cavity output signals proportional to ring perpendicular energy. A data analysis technique is described, which in its simplest form is subtracting 1/4 the signal from each neighboring cavity pickup loop from the central one's, which provides a signal proportional to the energy in a single ring. The calibration factor relating absolute perpendicular energy to diamagnetic signal depends weakly on the geometrical model for the ring. Calculations with a bumpy cylinder MHD equilibrium code give calibration factors in reasonable agreement (20%) to the values obtained using a simple, concentric cylindrical current sheet model. The cylindrical current sheet model is used to show that diamagnetic field components measured external to the plasma require high precision or correlation with other diagnostics in order to fix model parameters. A computer simulation shows an assumption of constant ring thickness and energy density with increasing length (and energy) is compatible to diamagnetic field observations on NBT

  10. All Prime Contract Awards by State or Country, Place, and Contractor. Part 18 (Elmo Texas-San Saba Texas)

    Science.gov (United States)

    1990-01-01

    on1 C> up0) 11 ca (-4N4 tax to "I toN >- >- (ao ro Y t ’C/ ACCA #IN ION to4 1,1 4100M I(-4 0 II Z £22 ( xz22 x2222 xZzz x Z x Z x Z x Z a (00 W 022* 02...0 OLU -IL 0 - I >0 ɛ 0 330 L’) I’ it1 0 0 (00 00 oleI3 < ifC’ F3 - r-CP,-’- - r--- in)-I -4N I (S0 M)-4 P.3) NNcq ’) to( M .N .4 0a 343 <’) 3it n-4

  11. Elmo Bumpy Torus proof of principle. Phase II. Title 1 report. Volume III. Magnet system. Preliminary design report

    International Nuclear Information System (INIS)

    Ackerman, S.

    1982-01-01

    During Title I, General Dynamics' principal role as a subcontractor to the McDonnell Douglas Astronautics Company (MDAC) is to assist in the further development of a low-cost superconducting magnet mirror coil system for the EBT-P program consistent with long life and dependable operation. The activity can best be defined as an extension of ORNL's previous development program with further joint ORNL/MDAC/GDC refining of the mirror coil components. MDAC/GDC participation for the entire program can be subdivided into four distinct elements as follows: (1) design, development, and fabrication of two dewar subassemblies to enclose the ORNL developed and fabricated cold mass assemblies; (2) design, development, and fabrication of a production prototype magnet system including conductor (procurement), cold mass components, dewar and x-ray shield. This prototype would form the basis for the production of 36 magnets for the torus and three spares. (3) design, development, and fabrication of an electrical/electronic system including quench protection, instrumentation and control, and power supply to power and protect the mirror coil system during its operation in the torus; (4) fabrication of the 39 production magnets

  12. Elmo Bumpy Torus proof of principle, Phase II: Title 1 report. Volume IV. Microwave system. Preliminary design report

    International Nuclear Information System (INIS)

    Adams, R.N.

    1982-01-01

    The EBT-P Microwave System provides microwaves for electron cyclotron resonance heating (ECRH) to both stabilize and heat the EBT-P plasma. A 28 gigahertz (GHz) system is required to form the hot electron annulus plasma that provides MHD stabilization to the core plasma. A 60 GHz system is required to heat the core plasma and will provide some second harmonic heating of the hot electron annulus. The principal microwave system elements and their design characteristics are summarized. The microwave system includes 200 kilowatt (kW) gyrotrons at 60 GHz for core heating and 200 kW gyrotrons at 28 GHz for annulus heating. The basic operating complement will be six (6) 60 GHz tubes and two (2) 28 GHz tubes. PACE (Plant and Capital Equipment) procurement will include four (4) 60 GHz gyrotrons with two (2) GHz tubes procured under operations and the two (2) 28 GHz tubes will be provided, with mounts, from the EBT-S program. Each tube is rigidly mounted on an oil filled tank assembly which provides electrical isolation and cooling. All tubes and mounts will be located in the lower level of the torus enclosure. An extensive demineralized water flow system is required to provide gyrotron cooling

  13. Radial structure of curvature-driven instabilities in a hot-electron plasma

    International Nuclear Information System (INIS)

    Spong, D.A.; Berk, H.L.; Van Dam, J.W.

    1984-01-01

    A nonlocal analysis of curvature-driven instabilities for a hot-electron ring interacting with a warm background plasma has been made. Four different instability modes characteristic of hot-electron plasmas have been examined: the high-frequency hot-electron interchange (at frequencies larger than the ion-cyclotron frequency), the compressional Alfven instability, the interacting background pressure-driven interchange, and the conventional hot-electron interchange (at frequencies below the ion-cyclotron frequency). The decoupling condition between core and hot-electron plasmas has also been examined, and its influence on the background and hot-electron interchange stability boundaries has been studied. The assumed equilibrium plasma profiles and resulting radial mode structure differ somewhat from those used in previous local analytic estimates; however, when the analysis is calibrated to the appropriate effective radial wavelength of the nonlocal calculation, reasonable agreement is obtained. Comparison with recent experimental measurements indicates that certain of these modes may play a role in establishing operating boundaries for the ELMO Bumpy Torus-Scale (EBT-S) experiment. The calculations given here indicate the necessity of having core plasma outside the ring to prevent the destabilizing wave resonance of the precessional mode with a cold plasma

  14. Effect of the radial electric field on turbulence

    International Nuclear Information System (INIS)

    Carreras, B.A.; Lynch, V.E.

    1990-01-01

    For many years, the neoclassical transport theory for three- dimensional magnetic configurations, such as magnetic mirrors, ELMO Bumpy Tori (EBTs), and stellarators, has recognized the critical role of the radial electric field in the confinement. It was in these confinement devices that the first experimental measurements of the radial electric field were made and correlated with confinement losses. In tokamaks, the axisymmetry implies that the neoclassical fluxes are ambipolar and, as a consequence, independent of the radial electric field. However, axisymmetry is not strict in a tokamak with turbulent fluctuations, and near the limiter ambipolarity clearly breaks down. Therefore, the question of the effect of the radial electric field on tokamak confinement has been raised in recent years. In particular, the radial electric field has been proposed to explain the transition from L-mode to H-mode confinement. There is some initial experimental evidence supporting this type of explanation, although there is not yet a self-consistent theory explaining the generation of the electric field and its effect on the transport. Here, a brief review of recent results is presented. 27 refs., 4 figs

  15. Stability of EBT of guiding-centre fluid theory

    International Nuclear Information System (INIS)

    Miller, R.L.

    1981-01-01

    The stability of the hot-electron annulus in the ELMO Bumpy Torus (EBT) is not yet completely understood despite considerable attention. Most stability studies have dealt with localized analysis of simplified models in which the actual magnetic configuration is replaced by a straight-line slab with a gravity to emulate the effects of curvature and gradients in the actual magnetic field. Here, a more realistic geometry, a 'bumpy' cylinder with a 2:1 magnetic mirror ratio, is considered and the response of the hot-electron rings to various non-local perturbations, specifying only the mode number in the ignorable co-ordinate, is examined. Guiding-centre theory (with psub(perpendicular) > psub(parallel)) is used and the second variation in the plasma energy (σW) using a finite-element representation to identify the least stable mode for the plasma is studied. All the equilibria that are examined are found to be unstable for all poloidal mode numbers m>=1, with growth rates increasing with increasing ring beta, plasma beta, and poloidal mode number. It is concluded that two-fluid and/or kinetic effects are required to explain the observed global stability of EBT-I. (author)

  16. Natural CO2 Analogs for Carbon Sequestration

    Energy Technology Data Exchange (ETDEWEB)

    Scott H. Stevens; B. Scott Tye

    2005-07-31

    The report summarizes research conducted at three naturally occurring geologic CO{sub 2} fields in the US. The fields are natural analogs useful for the design of engineered long-term storage of anthropogenic CO{sub 2} in geologic formations. Geologic, engineering, and operational databases were developed for McElmo Dome in Colorado; St. Johns Dome in Arizona and New Mexico; and Jackson Dome in Mississippi. The three study sites stored a total of 2.4 billion t (46 Tcf) of CO{sub 2} equivalent to 1.5 years of power plant emissions in the US and comparable in size with the largest proposed sequestration projects. The three CO{sub 2} fields offer a scientifically useful range of contrasting geologic settings (carbonate vs. sandstone reservoir; supercritical vs. free gas state; normally pressured vs. overpressured), as well as different stages of commercial development (mostly undeveloped to mature). The current study relied mainly on existing data provided by the CO{sub 2} field operator partners, augmented with new geochemical data. Additional study at these unique natural CO{sub 2} accumulations could further help guide the development of safe and cost-effective design and operation methods for engineered CO{sub 2} storage sites.

  17. Effect of electric fields and fluctuations on confinement in a bumpy torus

    International Nuclear Information System (INIS)

    Hiroe, S.; Glowienka, J.C.; Hillis, D.L.

    1986-06-01

    In order to understand the relationships between confinement and space potential (electric field) and between confinement and density fluctuations, plasma parameters in the ELMO Bumpy Torus Scale (EBT-S) have been measured systematically for a wide range of operating conditions. Present EBT plasma parameters do not show a strong dependence on the potential profile, but rather exhibit a correlation with the fluctuations. The plasma pressure profile is found to be consistent with the profile anticipated on the basis of the flute stability criterion for a marginally stable plasma. For a heating power of 100 kW, the stored energy density is found to be restricted to the range between 4.5 x 10 13 eV-cm -3 and 7 x 10 13 eV-cm -3 . The lower limit remains constant regardless of heating power and pertains to plasmas lacking an equilibrium and/or stability. The upper limit increases with heating power and is found to result from the onset of instabilities. In between the two limits is a plasma that is in an equilibrium state and is marginally stable. Operational trajectories exist that take the EBT plasma from one limit to the other

  18. Characterizing Microbial Diversity and Function in Natural Subsurface CO2 Reservoir Systems for Applied Use in Geologic Carbon Sequestration Environments

    Science.gov (United States)

    Freedman, A.; Thompson, J. R.

    2013-12-01

    The injection of CO2 into geological formations at quantities necessary to significantly reduce CO2 emissions will represent an environmental perturbation on a continental scale. The extent to which biological processes may play a role in the fate and transport of CO2 injected into geological formations has remained an open question due to the fact that at temperatures and pressures associated with reservoirs targeted for sequestration CO2 exists as a supercritical fluid (scCO2), which has generally been regarded as a sterilizing agent. Natural subsurface accumulations of CO2 serve as an excellent analogue for studying the long-term effects, implications and benefits of CO2 capture and storage (CCS). While several geologic formations bearing significant volumes of nearly pure scCO2 phases have been identified in the western United States, no study has attempted to characterize the microbial community present in these systems. Because the CO2 in the region is thought to have first accumulated millions of years ago, it is reasonable to assume that native microbial populations have undergone extensive and unique physiological and behavioral adaptations to adjust to the exceedingly high scCO2 content. Our study focuses on the microbial communities associated with the dolomite limestone McElmo Dome scCO2 Field in the Colorado Plateau region, approximately 1,000 m below the surface. Fluid samples were collected from 10 wells at an industrial CO2 production facility outside Cortez, CO. Subsamples preserved on site in 3.7% formaldehyde were treated in the lab with Syto 9 green-fluorescent nucleic acid stain, revealing 3.2E6 to 1.4E8 microbial cells per liter of produced fluid and 8.0E9 cells per liter of local pond water used in well drilling fluids. Extracted DNAs from sterivex 0.22 um filters containing 20 L of sample biomass were used as templates for PCR targeting the 16S rRNA gene. 16S rRNA amplicons from these samples were cloned, sequenced and subjected to microbial

  19. Elmo Bumpy Torus proof of principle, Phase II: Title 1 report. Volume V. Vacuum-pumping system. Preliminary design report

    International Nuclear Information System (INIS)

    1982-01-01

    This report summarizes Title I Preliminary Design of the EBT-P Vacuum Pumping System. The Vacuum Pumping System has been designed by the McDonnell Douglas Astronautics Co. - St. Louis (MDAC). It includes the necessary vacuum pumps and vacuum valves to evacuate the torus, the Mirror Coil Dewars (MC Dewars), and the Gyrotron Magnet Dewars. The pumping ducts, manifolds, and microwave protection system are also included. A summary of the function of each subsystem and a description of its principle components is provided below. The analyses performed during the system design are also identified

  20. Sulphur bacteria mediated formation of Palaeoproterozoic phosphorites

    Science.gov (United States)

    Joosu, Lauri; Lepland, Aivo; Kirsimäe, Kalle

    2014-05-01

    . Moreover, P-rich intervals in the Zaonega Formation are found in organic-rich sediments exhibiting strongly negative δ13Corg values (-37 to -34 per mil) which is interpreted to reflect the methanotrophic biomass. We conclude that modern-style phosphogenesis, mediated by sulphide-oxidising bacteria living in consortium with methanotrophs, was established at least 2 Ga ago. [1] Schulz and Schulz (2005) Science 307, 416-418 [2] Lepland, Joosu, Kirsimäe, Prave, Romashkin, Črne, Martin, Fallick, Somelar, Üpraus, Mänd, Roberts, van Zuilen, Wirth, Schreiber (2014) Nature geoscience 7, 20-24 [3] Bailey, Joye, Kalanetra, Flood, and Corsetti (2007) Nature 445, 198-201 [4] Schulz, Brinkhoff, Ferdelman, Marine, Teske and Jorgensen (1999) Science 284, 493-495 [5] Knittel, Losekann, Boetius, Kort and Amann (2005) Applied and Environmental Microbiology 71, 467-479.

  1. Simple annulus power balance in EBT-I

    International Nuclear Information System (INIS)

    Borowski, S.K.; Uckan, N.A.; Jaeger, E.F.; Kammash, T.

    1979-09-01

    An essential feature of the ELMO Bumpy Torus (EBT) concept is the presence of a relativistic electron annulus in each of the toroidal mirror sectors. These high beta annuli are formed and sustained by microwave heating and are of sufficient density and temperature that diamagnetic currents produce the necessary minimum in the magnetic field required for MHD stability of the toroidal core plasma. Because electron rings play an important role in confinement characteristics and performance of EBT, the trade-off between the quality of the confinement afforded by the rings and the power required to sustain the rings represents an important problem in a fusion reactor. Theoretical estimates of the microwave power required to sustain the annulus are found to be within a factor of 2 of the experimentally determined value. Scaling projections that are shown for both EBT-I and EBT-S enable one to examine the sensitivity of the annulus electron temperature as a function of core plasma density for various microwave power levels. The results are found to be sensitive to the details of the hot electron distribution function as well as geometric and scaling parameters. Improvements to the model are under way in order to increase its capability and accuracy in assessing the overall power balance

  2. Analysis of mixed mode microwave distribution manifolds

    International Nuclear Information System (INIS)

    White, T.L.

    1982-09-01

    The 28-GHz microwave distribution manifold used in the ELMO Bumpy Torus-Scale (EBT-S) experiments consists of a toroidal metallic cavity, whose dimensions are much greater than a wavelength, fed by a source of microwave power. Equalization of the mixed mode power distribution ot the 24 cavities of EBT-S is accomplished by empirically adjusting the coupling irises which are equally spaced around the manifold. The performance of the manifold to date has been very good, yet no analytical models exist for optimizing manifold transmission efficiency or for scaling this technology to the EBT-P manifold design. The present report develops a general model for mixed mode microwave distribution manifolds based on isotropic plane wave sources of varying amplitudes that are distributed toroidally around the manifold. The calculated manifold transmission efficiency for the most recent EBT-S coupling iris modification is 90%. This agrees with the average measured transmission efficiency. Also, the model predicts the coupling iris areas required to balance the distribution of microwave power while maximizing transmission efficiency, and losses in waveguide feeds connecting the irises to the cavities of EBT are calculated using an approach similar to the calculation of mainfold losses. The model will be used to evaluate EBT-P manifold designs

  3. Baby Elmo Leads Dads Back to the Nursery: How a Relationship-Based Intervention for Incarcerated Fathers Enhances Father and Child Outcomes

    Science.gov (United States)

    Richeda, Benjamin; Smith, Kelly; Perkins, Emily; Simmons, Sydney; Cowan, Philip; Cowan, Carolyn Pape; Rodriguez, Jennifer; Shauffer, Carole

    2015-01-01

    Although children's contact with involved, committed, nonresidential fathers can improve social, emotional, cognitive, and academic outcomes, fathers have largely been absent from parenting interventions that overlook men's role as a critical parenting partner. This article details research showing that young incarcerated fathers' attitudes…

  4. An experimental determination of the hot electron ring geometry in a Bumpy Torus and its implications for Bumpy Torus stability

    International Nuclear Information System (INIS)

    Hillis, D.L.; Wilgen, J.B.; Bigelow, T.S.; Jaeger, E.F.; Swain, D.W.; Hankins, O.E.; Juhala, R.E.

    1986-10-01

    The hot electron rings of the ELMO Bumpy Torus (EBT) [Plasma Physics and Controlled Nuclear Fusion (IAEA, Vienna, 1975), Vol. II, p. 141] are formed by electron cyclotron resonance heating (ECRH) and have an electron temperature of 350 to 500 keV. The original intention of these hot electron rings was to provide a local minimum in the magnetic field and, thereby, stabilize the simple interchange and flute modes, which are inherent in a closed field line bumpy torus. To evaluate the electron energy density of the EBT rings and determine if enough stored energy is present to provide a local minimum in the magnetic field, a detailed understanding of the spatial distribution of the rings is imperative. The purpose of this report is to measure the ring thickness and investigate its implications for bumpy torus stability. The spatial location and radial profile of the hot electron ring are measured with a unique metal ball pellet injector, which injects small metallic balls into the EBT ring plasma. From these measurements the radial extent (or ring thickness) is about 5 to 7 cm full width at half maximum for typical EBT operation, which is much larger than previously expected. These measurements and recent modeling of the EBT plasma indicate that the hot electron ring's stored energy may not be sufficient to produce a local minimum in the magnetic field

  5. New archaeorthopteran insects from the Late Carboniferous of the Nord and Pas-de-Calais basins in northern France (Insecta: Cnemidolestodea, Panorthoptera).

    Science.gov (United States)

    Coty, David; Háva, Jiří; Prokop, Jakub; Roques, Patrick; Nel, André

    2014-10-29

    New polyneopteran insects are described from Pennsylvanian (Bashkirian, Moscovian) compressed fossils from the North of France (Insecta: Archaeorthoptera). Discovery of wing apex with distinct venation, e.g., apical fusion of RA with RP, numerous parallel posterior branches of RP with transversal crossveins, can be assigned to cf. Tococladus sp. (Cnemidolestodea: Tococladidae). It represents the second record of Cnemidolestodea from the Avion locality apart from Aviocladus pectinatus Prokop et al., 2014. Bruaylogus magnificus gen. et sp. nov., based on forewing venation, is attributed to Panorthoptera nec Orthoptera having some distinct characters for the placement either close to Oedischiidae or a more basal position possibly with affinities to genus Heterologus. Aviologus duquesnei gen. et sp. nov., based on forewing venation, differs from Oedischiidae by the presence of basal fork of M far from point of separation between M and Cu and fusion of MA with first posterior branch of RP. Aviologus share a long stem of M and simple CuPaβ with Heterologus duyiwuer and H. langfordorum, but both differ in well separated median and radial veins. These new fossils demonstrate that the archaeorthopterid insect fauna from the North of France was rather diverse with links to late Carboniferous and early Permian assemblages in Euramerica such as the Mazon Creek, Carbondale Formation or Elmo, Wellington Formation (Illinois, Kansas, USA) entomofaunas.

  6. Electron-confinement studies on EBT-S using soft-x-ray techniques

    International Nuclear Information System (INIS)

    Hillis, D.L.; Haste, G.R.; Berry, L.A.

    1982-08-01

    Soft x-ray bremsstrahlung measurements have been performed on the ELMO Bumpy Torus (EBT-S) plasma to determine the electron temperature T/sub e/ and electron density n/sub e/ using a calibrated Si(Li) detector over a wide range of operating conditions. The purpose of this paper is to outline the necessary assumptions and essential x-ray techniques that are inherent in soft x-ray measurements in order to investigate the electron heating and confinement properties of EBT-S. In addition, by utilizing the electron density as determined by the soft x-ray measurements, the previous EBT-S confinement analyses have been extended. The steady-state plasma of EBT-S is heated by microwaves using a cw gyrotron that can operate up to power levels of 200 kW. From the soft x-ray measurements, both the electron temperature and density are found to increase at higher microwave power levels. For operation at microwave power levels of 200 kW, T/sub e/ approaches 1 keV while n/sub e/ approaches 1.2 x 10 12 cm -3 . In general, confinement properties are found to improve with increased microwave power. The data are compared with neoclassical transport scaling and the electron transport is found to be collisionless (nu/Ω < 1) as well as neoclassical

  7. Electron confinement studies on the EBT-S Bumpy Torus Experiment using soft x-ray techniques

    International Nuclear Information System (INIS)

    Hillis, D.L.; Haste, G.R.; Berry, L.A.

    1983-01-01

    Soft x-ray bremsstrahlung measurements have been performed on the ELMO Bumpy Torus (EBT-S) plasma to determine the electron temperature T/sub e/ and electron density density n/sub e/ using a calibrated Si(Li) detector over a wide range of operating conditions. The purpose of this paper is to outline the necessary assumptions and essential x-ray techniques that are inherent in soft x-ray measurements in order to investigate the electron heating and confinement properties of EBT-S. In addition, by utilizing the electron density as determined by the soft x-ray measurements, the previous EBT-S confinement analyses have been extended. The steady-state plasma of EBT-S is heated by microwaves using a continuous wave (cw) gyrotron that can operate up to power levels of 200 kW. From the soft x-ray measurements, both the electron temperature and density are found to increase at higher microwave power levels. For operation at microwave power levels of 200 kW, T/sub e/ approaches 1 keV while n/sub e/ approaches 1.2 x 10 12 cm - 3 . In general, confinement properties are found to improve with increased microwave power. The data are compared with neoclassical transport scaling and the electron transport is found to be collisionless (#betta#/Ω<1) as well as neoclassical

  8. Oak Ridge rf Test Facility

    International Nuclear Information System (INIS)

    Gardner, W.L.; Hoffman, D.J.; McCurdy, H.C.; McManamy, T.J.; Moeller, J.A.; Ryan, P.M.

    1985-01-01

    The rf Test Facility (RFTF) of Oak Ridge National Laboratory (ORNL) provides a national facility for the testing and evaluation of steady-state, high-power (approx.1.0-MW) ion cyclotron resonance heating (ICRH) systems and components. The facility consists of a vacuum vessel and two fully tested superconducting development magnets from the ELMO Bumpy Torus Proof-of-Principle (EBT-P) program. These are arranged as a simple mirror with a mirror ratio of 4.8. The axial centerline distance between magnet throat centers is 112 cm. The vacuum vessel cavity has a large port (74 by 163 cm) and a test volume adequate for testing prototypic launchers for Doublet III-D (DIII-D), Tore Supra, and the Tokamak Fusion Test Reactor (TFTR). Attached to the internal vessel walls are water-cooled panels for removing the injected rf power. The magnets are capable of generating a steady-state field of approx.3 T on axis in the magnet throats. Steady-state plasmas are generated in the facility by cyclotron resonance breakdown using a dedicated 200-kW, 28-GHz gyrotron. Available rf sources cover a frequency range of 2 to 200 MHz at 1.5 kW and 3 to 18 MHz at 200 kW, with several sources at intermediate parameters. Available in July 1986 will be a >1.0-MW, cw source spanning 40 to 80 MHz. 5 figs

  9. Error field generation of solenoid magnets

    International Nuclear Information System (INIS)

    Saunders, J.L.

    1982-01-01

    Many applications for large solenoids and solenoidal arrays depend on the high precision of the axial field profile. In cases where requirements of ΔB/B for nonaxial fields are on the order of 10 -4 , the actual winding techniques of the solenoid need to be considered. Whereas an ideal solenoid consisting of current loops would generate no radial fields along the axis, in reality, the actual current-carrying conductors must follow spiral or helical paths. A straightforward method for determining the radial error fields generated by coils wound with actual techniques employed in magnet fabrication has been developed. The method devised uses a computer code which models a magnet by sending a single, current-carrying filament along the same path taken by the conductor during coil winding. Helical and spiral paths are simulated using small, straight-line current segments. This technique, whose results are presented in this paper, was used to predict radial field errors for the Elmo Bumpy Torus-Proof of Principle magnet. These results include effects due to various winding methods, not only spiral/helical and layer-to-layer transitions, but also the effects caused by worst-case tolerance conditions both from the conductor and the winding form (bobbin). Contributions made by extraneous circuitry (e.g., overhead buswork and incoming leads) are also mentioned

  10. Physics and engineering aspects of the EBT reactor

    International Nuclear Information System (INIS)

    Uckan, N.A.; Bettis, E.S.; Hedrick, C.L.; Santoro, R.T.; Watts, H.L.; Yeh, H.T.

    1977-01-01

    The ELMO Bumpy Torus (EBT) reactor has the advantage of high-β, steady-state operation. The first reactor study based on the EBT confinement concept was initiated in 1976. It provided the required starting point for continued assessment of the validity of the concept. A new design based on the present physics understanding, practical design approaches, and present and near-term technologies has been established. One of the important factors in an EBT reactor is the large aspect ratio (large toroidal major radius as well). This leads to a power plant with a comparatively large total energy output, usually in the range of 2000-6000 MW(th) for a conventional neutron wall loading of 1-2 MW/m 2 (the high value of β in an EBT device provides a net cost per unit energy roughly equal to or somewhat less than that for a Tokamak system). The large aspect ratio also provides very simple engineering and design requirements because of good access and small force loading asymmetries. Another important factor is the steady-state operation. In an EBT system, less power handling, energy storage, and filtering equipment will be needed. An EBT reactor is less likely to be subject to thermal and mechanical fatigue than reactors with large pulsed magnetic fields and short bursts of fusion power. The details of the key design elements and critical scientific and technology factors which are substantially different from other fusion reactor approaches are described

  11. Assessment of historical surface-water quality data in southwestern Colorado, 1990-2005

    Science.gov (United States)

    Miller, Lisa D.; Schaffrath, Keelin R.; Linard, Joshua I.

    2013-01-01

    The spatial and temporal distribution of selected physical and chemical surface-water-quality characteristics were analyzed at stream sites throughout the Dolores and San Juan River Basins in southwestern Colorado using historical data collected from 1990 through 2005 by various local, State, Tribal, and Federal agencies. Overall, streams throughout the study area were well oxygenated. Values of pH generally were near neutral to slightly alkaline throughout most of the study area with the exception of the upper Animas River Basin near Silverton where acidic conditions existed at some sites because of hydrothermal alteration and(or) historical mining. The highest concentrations of dissolved aluminum, total recoverable iron, dissolved lead, and dissolved zinc were measured at sites located in the upper Animas River Basin. Thirty-two sites throughout the study area had at least one measured concentration of total mercury that exceeded the State chronic aquatic-life criterion of 0.01 μg/L. Concentrations of dissolved selenium at some sites exceeded the State chronic water-quality standard of 4.6 μg/L. Total ammonia, nitrate, nitrite, and total phosphorus concentrations generally were low throughout the study area. Overall, results from the trend analyses indicated improvement in water-quality conditions as a result of operation of the Paradox Valley Unit in the Dolores River Basin and irrigation and water-delivery system improvements made in the McElmo Creek Basin (Lower San Juan River Basin) and Mancos River Valley (Upper San Juan River Basin).

  12. Genetic Epidemiology of Type 2 Diabetes in Mexican Mestizos

    Directory of Open Access Journals (Sweden)

    Eiralí Guadalupe García-Chapa

    2017-01-01

    Full Text Available There are currently about 415 million people with diabetes worldwide, a figure likely to increase to 642 million by 2040. In 2015, Mexico was the second Latin American country and sixth in the world in prevalence of this disorder with nearly 11.5 million of patients. Type 2 diabetes (T2D is the main kind of diabetes and its etiology is complex with environmental and genetic factors involved. Indeed, polymorphisms in several genes have been associated with this disease worldwide. To estimate the genetic epidemiology of T2D in Mexican mestizos a systematic bibliographic search of published articles through PubMed, Scopus, Google Scholar, and Web of Science was conducted. Just case-control studies of candidate genes about T2D in Mexican mestizo inhabitants were included. Nineteen studies that met the inclusion criteria were found. In total, 68 polymorphisms of 41 genes were assessed; 26 of them were associated with T2D risk, which were located in ABCA1, ADRB3, CAPN10, CDC123/CAMK1D, CDKAL1, CDKN2A/2B, CRP, ELMO1, FTO, HHEX, IGF2BP2, IRS1, JAZF1, KCNQ1, LOC387761, LTA, NXPH1, SIRT1, SLC30A8, TCF7L2, and TNF-α genes. Overall, 21 of the 41 analyzed genes were associated with T2D in Mexican mestizos. Such a genetic heterogeneity compares with findings in other ethnic groups.

  13. Noise pollution survey of a two-storey intersection station in Tehran metropolitan subway system.

    Science.gov (United States)

    Ghotbi, Mohammad Reza; Monazzam, Mohammad Reza; Baneshi, Mohammad Reza; Asadi, Mohammad; Fard, Samaneh Momen Bellah

    2012-01-01

    According to the world population increase and demand on transportation in mega cities, modern and low-cost technologies are remarkably considered. Meanwhile, subway system, as a means to transfer a large population of people, is extremely welcomed due to its particular advantages including time and cost savings, traffic jam avoidance, and unaffected by weather. Nevertheless, despite the benefits of these technologies, such devices also have been associated with disadvantages for human. In many subway systems, noisy environments are clearly observed; therefore, workers and even the passengers are exposed to higher noise levels than permissible limit. In this research, noise measurements were performed at Imam Khomeini Station as the most crowded intersection subway station in Tehran. In this descriptive-sectional survey, the amount of noise pollution was investigated at both stories of Imam Khomeini Intersection Station. A variety of noise pollution indicators such as L(eq) 10 min were separately measured at each storey through five measurement points from 7 A.M. to 10 P.M. It was shown that the equivalent sound level range at Imam Khomeini station towards Elmo Sanat and Imam Khomeini towards Mirdamad were between 70.56-79.54 and 68.35-79.12 dB (A), respectively. It was indicated that except for the entrance stairs to the subway waiting platform and the first section of the platform on both stories, other measurement stations have the same equivalent sound levels.

  14. Equilibrium: three-dimensional configurations

    International Nuclear Information System (INIS)

    Anon.

    1987-01-01

    This chapter considers toroidal MHD configurations that are inherently three-dimensional. The motivation for investigation such complicated equilibria is that they possess the potential for providing toroidal confinement without the need of a net toroidal current. This leads to a number of advantages with respect to fusion power generation. First, the attractive feature of steady-state operation becomes more feasible since such configurations no longer require a toroidal current transformer. Second, with zero net current, one potentially dangerous class of MHD instabilities, the current-driven kink modes, is eliminated. Finally, three-dimensional configurations possess nondegenerate flux surfaces even in the absence of plasma pressure and plasma current. Although there is an enormous range of possible three-dimensional equilibria, the configurations of interest are accurately described as axisymmetric tori with superimposed helical fields; furthermore, they possess no net toroidal current. Instead, two different and less obvious restoring forces are developed: the helical sideband force and the toroidal dipole current force. Each is discussed in detail in Chapter 7. A detailed discussion of the parallel current constraint, including its physical significance, is given in section 7.2. A general analysis of helical sideband equilibria, along with a detailed description of the Elmo bumpy torus, is presented in sections 7.3 and 7.4. A general description of toroidal dipole-current equilibria, including a detailed discussion of stellarators, heliotrons, and torsatrons, is given in sections 7.5 and 7.6

  15. A modified culture-based study of bacterial community composition in a tannery wastewater treatment plant.

    Science.gov (United States)

    Desta, Adey F; Dalhammer, Gunnel; Kittuva, Gunatrana R

    2010-01-01

    Though culture-independent methods have been used in preference to traditional isolation techniques for characterization of microbial community of wastewater treatment plants, it is difficult to widely apply this approach in resource-poor countries. The present study aimed to develop a test to identify the culturable portion of bacterial community in a high-strength wastewater. Wastewater samples were collected from nitrification-denitrification and settling tanks of the treatment plant of Elmo Leather AB tannery located in Borås, Sweden. After cultivating on nutrient agar with the optimal dilution (10⁻²), phenotypic and biochemical identification of the bacteria were done with colony morphology, Gram reaction, growth on MacConkey, phenylethanol media, triple sugar Iron agar slants, catalase and oxidase tests. Biochemical grouping of the isolates was done based on their test results for MacConkey, phenylethanol media, triple sugar Iron agar and oxidase test reaction. From the biochemical groups, isolates were randomly selected for API test and 16SrRNA gene sequencing. The isolates from the denitrification, nitrification tank were identified to be Paracoccus denitrificans (67%), Azoarcus spp (3%) and Spingomonas wittichii (1%). From the settling tank, Paracoccus denitrificans (22%), Corynebacterium freneyi (20%) and Bacillus cereus (1%) were identified. The grouping based on biochemical test results as well as the identification based on sequencing has shown coherence except for discrepancies with the API test. The preliminary implications of the grouping based on culture-based characteristics and its potential application for resource-limited environmental microbial studies is discussed.

  16. Genetic susceptibility to feline infectious peritonitis in Birman cats.

    Science.gov (United States)

    Golovko, Lyudmila; Lyons, Leslie A; Liu, Hongwei; Sørensen, Anne; Wehnert, Suzanne; Pedersen, Niels C

    2013-07-01

    Genetic factors are presumed to influence the incidence of feline infectious peritonitis (FIP), especially among pedigreed cats. However, proof for the existence of such factors has been limited and mainly anecdotal. Therefore, we sought evidence for genetic susceptibility to FIP using feline high density single nucleotide polymorphism (SNP) arrays in a genome-wide association study (GWAS). Birman cats were chosen for GWAS because they are highly inbred and suffer a high incidence of FIP. DNA from 38 Birman cats that died of FIP and 161 healthy cats from breeders in Denmark and USA were selected for genotyping using 63K SNPs distributed across the feline genome. Danish and American Birman cats were closely related and the populations were therefore combined and analyzed in two manners: (1) all cases (FIP) vs. all controls (healthy) regardless of age, and (2) cases 1½ years of age and younger (most susceptible) vs. controls 2 years of age and older (most resistant). GWAS of the second cohort was most productive in identifying significant genome-wide associations between case and control cats. Four peaks of association with FIP susceptibility were identified, with two being identified on both analyses. Five candidate genes ELMO1, RRAGA, TNFSF10, ERAP1 and ERAP2, all relevant to what is known about FIP virus pathogenesis, were identified but no single association was fully concordant with the disease phenotype. Difficulties in doing GWAS in cats and interrogating complex genetic traits were discussed. Copyright © 2013 Elsevier B.V. All rights reserved.

  17. Žanr : suvelavastus? / Jaak Allik

    Index Scriptorium Estoniae

    Allik, Jaak, 1946-

    2007-01-01

    Kahekümnest suvisest teatriõhtust: Carlo Gozzi "Ronk" Tallinna Linnateatri lavaaugus (lavastaja Elmo Nüganen), Komöödiateatri suvetuuri lavastus "Elu parim puhkus" (lavastaja Ago-Endrik Kerge), muusikal "Tutvumiskuulutus" (lavastaja Mait Malmsten), Bernard Kangermanni laulumäng "Naabri Mari" (lavastaja Margus Vaher) ja Mara Zalite "Sirelikassid" (lavastaja Peeter Tammearu) Ugalas, Paul Barzi komöödia "Võimalik kohtumine" (lavastaja Raivo Trass) Vanemuise teatri suvelavastus Muhumaal Pädaste mõisas, muusikaline estraadietendus "Tähtede sadu", Endla "Tsirkus!!!" Paikuse-Reiu vabaõhulaval (autor ja lavastaja Tiit Palu), Andrus Kivirähki näidend "Uljas Neitsi" Laulasmaa Resort' rannametsas (lavastaja Taavi Teplenkov), Marti Kivastik "Eesti asi" (lavastaja Ingomar Vihmar) MTÜ Ühendus R.A.A.A.M. Viinistu kunstimuuseumi vabaõhulaval, Emajõe Suveteatri suvelavastus "Jumalaema kiriku kellamees" Victor Hugo romaani järgi (lavastaja Andres Dvinjaninov), "Muna EÜE ehk Viimane kava" (autor Lauri Vahtre, lavastaja Andrus Vaarik) Suure Munamäe vabaõhulaval, Aino Kalda "Reigi õpetaja" Kuressaares (lavastaja ja dramatiseerija Aare Toikka), Vana Baskini Teateris Pierre Chesnot "Kes aevastas?" (lavastaja Eino Baskin), Eduard Vilde romaani "Prohvet Maltsvet" ja vene kirjaniku Viktor Pelevini romaani aineil sündinud lavastus "Proffet" Albu vallas Kukenoosi rehealuses (lavastaja Mart Koldits), Enn Vetemaa "Roosiaed" Raasiku vallas Kiviloo mõisas (lavastaja Eva Klemets), Jim Ashilevi "Portselansuits" (lavastaja Lauri Lagle) Eesti Teatriliidu saalis, Andres Keili "Rooside sõda" Leigo Järveteatris (lavastaja Tõnu Lensment), Võru Teatriateljee suvelavastus Madis Kõivu "Castrozza ehk illusionist" (lavastaja Taago Tubin), Villu Tamme "Haned võlgu" (lavastaja ja kunstnik Jaanika Juhanson) Teatrilabor Von Krahli teatris

  18. Magnetostratigraphy in the Lodo Formation, CA: An Attempt to Locate Hyperthermals of the Early Eocene

    Science.gov (United States)

    Aldrich, N. C.; Pluhar, C. J.; Gibbs, S.; Rieth, J. A.

    2015-12-01

    The Lodo Formation in the California Coast Range, Fresno County records the Paleocene Eocene Thermal Maximum (PETM) and possibly other Early Eocene hyperthermal events. The Eocene Thermal Maximum 2 (ETM2, ELMO, or H1) represents a hyperthermal event that occurred approximately 2 million years after the PETM and just prior to the C24r - C24n magnetic reversal (≈ 53.9 Ma) in the Ypresian. While the ETM2 event has been located in offshore samples, it has been more difficult to locate in a terrestrial section. This project attempts to locate the ETM2 magnetostratigraphically by finding the paleomagnetic reversal at C24r-C24n.3n, provide geochronological framework, and assess sedimentation rate changes during this time. This area is known to have had a high rate of deposition (16.8 cm/kyr ) during the PETM, which is found lower in the section. We collected 36 new samples from a 13.44m section spanning stratigraphy thought to cover the ETM2 along with 31 previous samples spanning the PETM, and prepared them for paleomagnetic and paleontological analysis. We analyzed samples using standard paleomagnetic methods including low-temperature and thermal demagnetization. Preliminary results suggest that the magnetostratigraphy spans the C24r-C24n boundary, while the micropaleontology shows the NP10-NP11 boundary, which occurs near the ETM2 as well as the NP11-NP12 boundary. The data indicate an order-of-magnitude drop in sedimentation rate in the lower Eocene at this site, concomitant with a drop in grain size, compared with the PETM.

  19. Hard x-ray measurements of the hot-electron rings in EBT-S

    International Nuclear Information System (INIS)

    Hillis, D.L.

    1982-06-01

    A thorough understanding of the hot electron rings in ELMO Bumpy Torus-Scale (EBT-S) is essential to the bumpy torus concept of plasma production, since the rings provide bulk plasma stability. The hot electrons are produced via electron cyclotron resonant heating using a 28-GHz cw gyrotron, which has operated up to power levels of 200 kW. The parameters of the energetic electron rings are studied via hard x-ray measurement techniques and with diamagnetic pickup coils. The hard x-ray measurements have used collimated NaI(Tl) detectors to determine the electron temperature T/sub e/ and electron density n/sub e/ for the hot electron annulus. Typical values of T/sub e/ are 400 to 500 keV and of n/sub e/ 2 to 5 x 10 11 cm -3 . The total stored energy of a single energetic electron ring as measured by diamagnetic pickup loops approaches approx. 40 J and is in good agreement with that deduced from hard x-ray measurements. By combining the experimental measurements from hard x-rays and the diamagnetic loops, an estimate can be obtained for the volume of a single hot electron ring. The ring volume is determined to be approx. 2.2 litres, and this volume remains approximately constant over the T-mode operating regime. Finally, the power in the electrons scattered out of the ring is measured indirectly by measuring the x-ray radiation produced when those electrons strike the chamber walls. The variation of this radiation with increasing microwave power levels is found to be consistent with classical scattering estimates

  20. Beta limits in EBT and their implications for a reactor

    International Nuclear Information System (INIS)

    Uckan, N.A.; Spong, D.A.; Nelson, D.B.

    1982-01-01

    Theoretical models indicate limits on core beta ranging from a few percent to 10-20% depending on the models and/or assumptions. Some of the parameters that enter into these beta limits are: the ratio of the ring radial scale length to the average radius of curvature, epsilon=Δ/Rsub(c); the ratio of the cold to the hot plasma density, fsub(R)=nsub(cold)/nsub(hot); the ratios of the hot electron drift frequency to the ion cyclotron frequency, ωsub(dh)/ωsub(ci), and to the drift Alfven frequency ωsub(dh)/kVsub(A); the ratio of the ring electron temperature to the core ion temperature, Tsub(R)/Tsub(i); the ring beta βsub(R); etc. Because of uncertainties in extrapolating results of simplifield models to a reactor plasma, the above parameters that influence the beta limits cannot be determined accurately at the present time. Also, reasonable changes within the models and/or assumptions are seen to affect the core beta limits by almost an order of magnitude. Hence, at the present, these limits cannot be used as a rigid (and reliable) requirement for ELMO Bumpy Torus (EBT) reactor engineering considerations. However, sensitivity studies can be carried out to determine the boundaries of the operating regime and to demonstrate the effects of various modes, assumptions, and models on reactor performance (Q value). First the modes believed to limit the core β and ring plasma performance are discussed, and the simplifications and/or assumptions involved in deriving these limits are highlighted. Then, the implications of these limits for a reactor are given. (author)

  1. Recent progress in the genetics of diabetic microvascularcomplications

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    Diabetic complications including diabetic nephropathy,retinopathy, and neuropathy are as major causesof morbidity and mortality in diabetes individualsworldwide and current therapies are still unsatisfactory.One of the reasons for failure to develop effectivetreatment is the lack of fundamental understanding forunderlying mechanisms. Genetic studies are powerfultools to dissect disease mechanism. The heritability (h 2)was estimated to be 0.3-0.44 for diabetic nephropathyand 0.25-0.50 for diabetic retinopathy respectively.Previous linkage studies for diabetic nephropathyhave identified overlapped linkage regions in 1q43-44,3 q 2 1 - 2 3 , 3 q 2 6 , 1 0 p 1 2 - 1 5 , 1 8 q 2 2 - 2 3 , 1 9 q 1 3 ,22q11-12.3 in multiple ethnic groups. Genome-wideassociation studies (GWAS) of diabetic nephropathyhave been conducted in several populations. However,most of the identified risk loci could not be replicatedby independent studies with a few exceptions includingthose in ELMO1 , FRMD3 , CARS , MYO16/IRS2 , andAPOL3-MYH9 genes. Functional studies of these genesrevealed the involvement of cytoskeleton reorganization(especially non-muscle type myosin), phagocytosis ofapoptotic cells, fibroblast migration, insulin signaling,and epithelial clonal expansion in the pathogenesisof diabetic nephropathy. Linkage analyses of diabeticretinopathy overlapped only in 1q36 region andcurrent results from GWAS for diabetic retinopathy areinconsistent. Conclusive results from genetic studies fordiabetic neuropathy are lacking. For now, small samplesizes, confounding by population stratification, differentphenotype definitions between studies, ethnic-specificassociations, the influence of environmental factors,and the possible contribution of rare variants mayexplain the inconsistencies between studies.

  2. Delivering services to incarcerated teen fathers: a pilot intervention to increase the quality of father-infant interactions during visitation.

    Science.gov (United States)

    Barr, Rachel; Morin, Marisa; Brito, Natalie; Richeda, Benjamin; Rodriguez, Jennifer; Shauffer, Carole

    2014-02-01

    The absence of a father figure has been linked to very poor developmental outcomes for the child. During incarceration, there are limited opportunities for visitation between fathers and their children. The Baby Elmo Program provides incarcerated teen fathers with parenting training and visitation with their children with the stated goal of enhancing father-child interactional quality. Forty-one incarcerated teen fathers and their infants ranging from 1 to 15 months of age participated in the present study. During individual sessions, a trained facilitator prepared fathers for visits with their children by introducing key concepts such as following the child's lead, using developmentally appropriate media to illustrate those concepts. After each training session, the incarcerated teen father interacted with his infant and the visit was video recorded. Analysis of the visit sessions focused on father's time use on different activities, the quality of father-infant interactions, and father's integration of target skills introduced in the intervention. The time-use analysis revealed that time use changed as a function of infant age. Growth linear modeling indicated that there were significant positive increases in the amount of parent support and infant engagement as a function of the number of sessions. Follow-up analyses indicated that changes between specific sessions mapped onto the target skills discussed during specific training sessions. This study's preliminary findings suggest that an intervention integrating visitation and appropriate media may be effective for incarcerated teen fathers. Due to the lack of a randomized control group, the present findings are exploratory and are discussed with a focus on further program development. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  3. RHOG-DOCK1-RAC1 Signaling Axis Is Perturbed in DHEA-Induced Polycystic Ovary in Rat Model.

    Science.gov (United States)

    Ubba, Vaibhave; Soni, Upendra Kumar; Chadchan, Sangappa; Maurya, Vineet Kumar; Kumar, Vijay; Maurya, Ruchika; Chaturvedi, Himanshu; Singh, Rajender; Dwivedi, Anila; Jha, Rajesh Kumar

    2017-05-01

    The function of RHOG, a RAC1 activator, was explored in the ovary during ovarian follicular development and pathological conditions. With the help of immunoblotting and immunolocalization, we determined the expression and localization of RHOG in normal (estrous cycle) and polycystic ovaries using Sprague Dawley (SD) rat model. Employing polymerase chain reaction and flow cytometry, we analyzed the transcript and expression levels of downstream molecules of RHOG, DOCK1, and RAC1 in the polycystic ovarian syndrome (PCOS) ovary along with normal antral follicular theca and granulosa cells after dehydroepiandrosterone (DHEA) supplementation. The effect of RHOG knockdown on DOCK1, VAV, and RAC1 expression was evaluated in the human ovarian cells (SKOV3), theca cells, and granulosa cells from SD rats with the help of flow cytometry. Oocyte at secondary follicles along with stromal cells showed optimal expression of RHOG. Immunoblotting of RHOG revealed its maximum expression at diestrus and proestrus, which was downregulated at estrus stage. Mild immunostaining of RHOG was also present in the theca and granulosa cells of the secondary and antral follicles. Polycystic ovary exhibited weak immunostaining for RHOG and that was corroborated by immunoblotting-based investigations. RHOG effectors DOCK1 and ELMO1 were found reduced in the ovary in PCOS condition/DHEA. RHOG silencing reduced the expression of DOCK1 and RAC1 in the theca and granulosa cells from SD rat antral follicles and that was mirrored in the human ovarian cells. Collectively, RHOG can mediate signaling through downstream effectors DOCK1 and RAC1 during ovarian follicular development (theca and granulosa cells and oocyte), but DHEA downregulated them in the PCOS ovary.

  4. Frequency modulation reveals the phasing of orbital eccentricity during Cretaceous Oceanic Anoxic Event II and the Eocene hyperthermals

    Science.gov (United States)

    Laurin, Jiří; Meyers, Stephen R.; Galeotti, Simone; Lanci, Luca

    2016-05-01

    Major advances in our understanding of paleoclimate change derive from a precise reconstruction of the periods, amplitudes and phases of the 'Milankovitch cycles' of precession, obliquity and eccentricity. While numerous quantitative approaches exist for the identification of these astronomical cycles in stratigraphic data, limitations in radioisotopic dating, and instability of the theoretical astronomical solutions beyond ∼50 Myr ago, can challenge identification of the phase relationships needed to constrain climate response and anchor floating astrochronologies. Here we demonstrate that interference patterns accompanying frequency modulation (FM) of short eccentricity provide a robust basis for identifying the phase of long eccentricity forcing in stratigraphic data. One- and two-dimensional models of sedimentary distortion of the astronomical signal are used to evaluate the veracity of the FM method, and indicate that pristine eccentricity FM can be readily distinguished in paleo-records. Apart from paleoclimatic implications, the FM approach provides a quantitative technique for testing and calibrating theoretical astronomical solutions, and for refining chronologies for the deep past. We present two case studies that use the FM approach to evaluate major carbon-cycle perturbations of the Eocene and Late Cretaceous. Interference patterns in the short-eccentricity band reveal that Eocene hyperthermals ETM2 ('Elmo'), H2, I1 and ETM3 (X; ∼52-54 Myr ago) were associated with maxima in the 405-kyr cycle of orbital eccentricity. The same eccentricity configuration favored regional anoxic episodes in the Mediterranean during the Middle and Late Cenomanian (∼94.5-97 Myr ago). The initial phase of the global Oceanic Anoxic Event II (OAE II; ∼93.9-94.5 Myr ago) coincides with maximum and falling 405-kyr eccentricity, and the recovery phase occurs during minimum and rising 405-kyr eccentricity. On a Myr scale, the event overlaps with a node in eccentricity

  5. Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ.

    Science.gov (United States)

    Erami, Zahra; Khalil, Bassem D; Salloum, Gilbert; Yao, Yanhua; LoPiccolo, Jaclyn; Shymanets, Aliaksei; Nürnberg, Bernd; Bresnick, Anne R; Backer, Jonathan M

    2017-11-16

    Phosphoinositide 3-kinases (PI 3-kinases) are regulated by a diverse range of upstream activators, including receptor tyrosine kinases (RTKs), G-protein-coupled receptors (GPCRs), and small GTPases from the Ras, Rho and Rab families. For the Class IA PI 3-kinase PI3Kβ, two mechanisms for GPCR-mediated regulation have been described: direct binding of Gβγ subunits to the C2-helical domain linker of p110β, and Dock180/Elmo1-mediated activation of Rac1, which binds to the Ras-Binding Domain of p110β. We now show that the integration of these dual pathways is unexpectedly complex. In breast cancer cells, expression of constitutively activated Rac1 (CA-Rac1) along with either GPCR stimulation or expression of Gβγ led to an additive PI3Kβ-dependent activation of Akt. Whereas CA-Rac1-mediated activation of Akt was blocked in cells expressing a mutated PI3Kβ that cannot bind Gβγ, Gβγ and GPCR-mediated activation of Akt was preserved when Rac1 binding to PI3Kβ was blocked. Surprisingly, PI3Kβ-dependent CA-Rac1 signaling to Akt was still seen in cells expressing a mutant p110β that cannot bind Rac1. Instead of directly binding to PI3Kβ, CA-Rac1 acts by enhancing Gβγ coupling to PI3Kβ, as CA-Rac1-mediated Akt activation was blocked by inhibitors of Gβγ. Cells expressing CA-Rac1 exhibited a robust induction of macropinocytosis, and inhibitors of macropinocytosis blocked the activation of Akt by CA-Rac1 or lysophosphatidic acid. Our data suggest that Rac1 can potentiate the activation of PI3Kβ by GPCRs through an indirect mechanism, by driving the formation of macropinosomes that serve as signaling platforms for Gβγ coupling to PI3Kβ. © 2017 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

  6. Scaling of Dielectric Breakdown Thresholds in Earth's and CO2-rich atmospheres: Impact for Predictions of Extraterrestrial Transient Luminous Events and Lightning Discharges

    Science.gov (United States)

    Riousset, J. A.

    2016-12-01

    Earth's atmospheric electricity manifests itself in the form of glow, corona, streamer, and leader discharges observed as Saint Elmo's fire, sprites, lightning and jets discharges, and other Transient Luminous Events (TLEs). All of these are types of dielectric breakdown, but are governed by different physics. In particular, their initiation is associated with the crossing of specific electric field thresholds: relativistic runaway, streamer propagation, conventional breakdown, or thermal runaway thresholds, some better understood than others. For example, the initiation of a lightning discharge is known to occur when the local electric field exceeds a value similar to relativistic runaway field, but the exact threshold, as well as the physical mechanisms at work, remain rather unclear to date. Scaling laws for electric fields (and other quantities) have been established by Pasko et al. [GRL, 25(12), 2123-2126, 1998] and Pasko [NATO Sci. Series, Springer, 253-311, 2006]. In this work, we develop profiles for initiation criteria in air and in other atmospheric environments. We further calculate their associated scaling laws to determine the ability to trigger lightning flashes and TLEs in our solar system. This lets us predict the likelihood of electrical discharges on, e.g., Mars, Venus and Titan, and calculate the expected electric field conditions, under which discharges have been observed on Jupiter, Saturn, Uranus, and Neptune [Leblanc et al., ISSI Spa. Sci. Series, Springer, 2008, Yair, Adv. Space Res., 50(3), 293-310, 2012]. Our results anticipate the arrival of ExoMars 2016's Schiaparelli module, which will provide the first records of electric field at the surface of the planet [Déprez et al., EGU GA, 16, 16613, 2014]. This research is also motived by the increasing probability of manned missions to Mars and the potential electrostatic hazards it may face [Yair, 2012], and by the role of electrical discharges in the creation of active radicals, some of

  7. Theoretical Investigations of Dielectric Breakdown in CO2: Implications for Atmospheric Discharges on Mars (and Venus)

    Science.gov (United States)

    Riousset, J. A.

    2017-12-01

    The detection of an atmospheric discharge in the Martian atmosphere by Ruf et al. [GRL, 36, L13202, 2009] supports the idea of a Martian atmospheric electric circuit [Farrell and Desch, JGR, 106, E4, 2001]. However, the lack of subsequent detection of similar events raises the question of the conditions of their initiation, and the existence of Martian lightning remains a controversial question. On Earth, atmospheric electricity manifests itself in the form of glow, corona, streamer, and leader discharges observed as Saint Elmo's fire, sprites, lightning and jets discharges, and other Transient Luminous Events (TLEs). All of these are dielectric breakdown governed by different physics. Their initiation is associated with the crossing of specific electric field thresholds: relativistic runaway, streamer propagation, conventional breakdown, or thermal runaway thresholds, some better understood than others. For example, the initiation of a lightning discharge is known to occur when the local electric field exceeds a value similar to relativistic runaway field, but the exact threshold, as well as the physical mechanisms at work, remain unclear to date. Scaling laws for electric fields (and other quantities) have been established by Pasko et al. [GRL, 25(12), 2123-2126, 1998] and Pasko [NATO Sci. Series, Springer, 253-311, 2006]. In this work, we develop profiles for initiation criteria in air and in other atmospheric environments. We further calculate their associated scaling laws to determine the ability to trigger lightning flashes and TLEs on Mars. This lets us predict the likelihood of electrical discharges and calculate the expected electric field conditions, under which discharges could be observed. We develop the analogy between Earth sand storm [Nicoll et al., Env. Res. Lett., 6, 014001, 2001] and Martian dust storms [Melnik and Parrot, JGR, 103(A12), 1998] to investigate the charge structure and resulting electric fields necessary to initiate dielectric

  8. Sõjakaadrite sobitamine isamaa ekraanidele. Sõda taasiseseisvumisjärgses eesti mängufilmis / Reframing War for the Nation-state’s Screens

    Directory of Open Access Journals (Sweden)

    Mari Laaniste

    2015-06-01

    Full Text Available Teesid: Artikkel vaatleb kriitiliselt 21. sajandi eesti mängufilmides peegelduvaid katseid rakendada militaartemaatika heroilise rahvusnarratiivi kujundamise ja edasikandmise teenistusse. Vaatluse keskmes on suund, mis koosneb seni kolmest mängufilmist ning ühest telesarjast ja telemängufilmist: „Nimed marmortahvlil“ (2002, „Detsembrikuumus“ (2008, „1944“ (2015 ja „Tuulepealne maa“ (2008, 2013. Teosed moodustavad temaatikalt ja lähenemiselt küllaltki homogeense terviku ning ka retseptsioon on kaldunud neid käsitlema sama riiklikult toetatud propagandadiskursuse osadena. Artikkel tõstab problemaatilisena esile, et filmide tootmises on osalenud ajaloolase taustaga poliitikud. SU M M A R Y This article traces and critiques attempts to reclaim militarism for patriotic purposes, as evidenced in early 21st century Estonian war-centred fiction films and TV series. Military themes were scarce in Estonia’s cinematic output during the 1990s, not so much due to their lingering association with Soviet propaganda, but rather because of economic hardship, which severely limited film budgets. However, as the ideological focus of the re-established nation-state came to rely heavily on nostalgia towards the interwar independence era, with its glorification of the victorious War of Independence, the emergence of „our own“ war films, intended to establish and perpetuate a heroic national narrative complete with military glory, seems to have been inevitable. The works primarily discussed here include the domestic box office hits Names in Marble (dir. Elmo Nüganen, 2002, December Heat (Asko Kase, 2008 and 1944 (Elmo Nüganen, 2015 as well as the popular TV series Windswept Land (Ain Prosa, 2008, 2013. While these productions are similar in many other ways, they are united by their straightforward patriotic pathos. There is a clear genre preference for epic historical dramas presented in a populist key, complete with spectacular

  9. Two-Phase Reactive Transport Model CO2-Brine at Hontomín Technological Development Plant (Burgos); Modelo de Transporte Reactivo Bifásico CO –Salmuera en el Emplazamiento de la Planta de Desarrollo Tecnológico de Hontomín (Burgos)

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigo-Naharro, J.; Recreo-Jiménez, F.

    2015-07-01

    The option of storing CO2 in carbonate formations is a minority in the literature on CO2 Deep Geological Storage (CO2-DGS). However, there is sufficient bibliography on systems where CO2 natural accumulations have remained for centuries in carbonate formations (e.g. McElmo Dome, USA), as well as projects related to the enhanced oil recovery (Weyburn Project, Canada). Both cases can represent natural or industrial analogues of a CO2-DGS. The Technological Development Plant (TDP) at Hontomín (Burgos) was initially designed to inject supercritical CO2 or dissolved CO2 in a Lower Jurassic limestone-dolomite formation of the Burgos Platform, at 1500 m depth approximately. The Dogger Aquifer in the Paris Basin, together with the overlying Albian aquifer, is one of these potential analogues of the Underground Structure of Hontomín due to their stratigraphic, lithological and hydrogeological similarities. However, the drilling of the wells HI (injection) and HA (auscultation) in the TDP at Hontomín in 2014, which have allowed to access to the storage and seal formations, as well as the petrophysical measurements performed by CIUDEN and Fundación Instituto Petrofísico on core samples from both wells, and the hydraulic tests for the dynamic reservoir characterisation, have advised to include the more permeable formation levels of the Norian-Rhaetian “carniolas” in the initially selected storage formation. This formation is located at the bottom of the Sopeña dolomitic Fm., at a depth of 1595-1605 m in the well HI. The existence of sulphates (anhydrite and gypsum) in these levels introduces lithological and geochemical features not present in the Dogger aquifer of the Paris Basin which, in turn, advises to consider the lessons learned from the Weyburn Project. In this report a study of the system CO2–brine–storage rock, close to the well HI, is presented, where the deep aquifer of the Underground Structure of Hontomín could be affected in the chemical

  10. Two-Phase Reactive Transport Model CO2-Brine at Hontomín Technological Development Plant (Burgos)

    International Nuclear Information System (INIS)

    Rodrigo-Naharro, J.; Recreo-Jiménez, F.

    2015-01-01

    The option of storing CO2 in carbonate formations is a minority in the literature on CO2 Deep Geological Storage (CO2-DGS). However, there is sufficient bibliography on systems where CO2 natural accumulations have remained for centuries in carbonate formations (e.g. McElmo Dome, USA), as well as projects related to the enhanced oil recovery (Weyburn Project, Canada). Both cases can represent natural or industrial analogues of a CO2-DGS. The Technological Development Plant (TDP) at Hontomín (Burgos) was initially designed to inject supercritical CO2 or dissolved CO2 in a Lower Jurassic limestone-dolomite formation of the Burgos Platform, at 1500 m depth approximately. The Dogger Aquifer in the Paris Basin, together with the overlying Albian aquifer, is one of these potential analogues of the Underground Structure of Hontomín due to their stratigraphic, lithological and hydrogeological similarities. However, the drilling of the wells HI (injection) and HA (auscultation) in the TDP at Hontomín in 2014, which have allowed to access to the storage and seal formations, as well as the petrophysical measurements performed by CIUDEN and Fundación Instituto Petrofísico on core samples from both wells, and the hydraulic tests for the dynamic reservoir characterisation, have advised to include the more permeable formation levels of the Norian-Rhaetian “carniolas” in the initially selected storage formation. This formation is located at the bottom of the Sopeña dolomitic Fm., at a depth of 1595-1605 m in the well HI. The existence of sulphates (anhydrite and gypsum) in these levels introduces lithological and geochemical features not present in the Dogger aquifer of the Paris Basin which, in turn, advises to consider the lessons learned from the Weyburn Project. In this report a study of the system CO2–brine–storage rock, close to the well HI, is presented, where the deep aquifer of the Underground Structure of Hontomín could be affected in the chemical

  11. Simulation and assessment of groundwater flow and groundwater and surface-water exchanges in lakes of the northeast Twin Cities Metropolitan Area, Minnesota, 2003 through 2013: Chapter B of Water levels and groundwater and surface-water exchanges in lakes of the northeast Twin Cities Metropolitan Area, Minnesota, 2002 through 2015

    Science.gov (United States)

    Jones, Perry M.; Roth, Jason L.; Trost, Jared J.; Christenson, Catherine A.; Diekoff, Aliesha L.; Erickson, Melinda L.

    2017-09-05

    Water levels during 2003 through 2013 were less than mean water levels for the period 1925–2013 for several lakes in the northeast Twin Cities Metropolitan Area in Minnesota. Previous periods of low lake-water levels generally were correlated with periods with less than mean precipitation. Increases in groundwater withdrawals and land-use changes have brought into question whether or not recent (2003–13) lake-water-level declines are solely caused by decreases in precipitation. A thorough understanding of groundwater and surface-water exchanges was needed to assess the effect of water-management decisions on lake-water levels. To address this need, the U.S. Geological Survey, in cooperation with the Metropolitan Council and the Minnesota Department of Health, developed and calibrated a three-dimensional, steady-state groundwater-flow model representing 2003–13 mean hydrologic conditions to assess groundwater and lake-water exchanges, and the effects of groundwater withdrawals and precipitation on water levels of 96 lakes in the northeast Twin Cities Metropolitan Area.Lake-water budgets for the calibrated groundwater-flow model indicated that groundwater is flowing into lakes in the northeast Twin Cities Metropolitan Area and lakes are providing water to underlying aquifers. Lake-water outflow to the simulated groundwater system was a major outflow component for Big Marine Lake, Lake Elmo, Snail Lake, and White Bear Lake, accounting for 45 to 64 percent of the total outflows from the lakes. Evaporation and transpiration from the lake surface ranged from 19 to 52 percent of the total outflow from the four lakes. Groundwater withdrawals and precipitation were varied from the 2003‒13 mean values used in the calibrated model (30-percent changes in groundwater withdrawals and 5-percent changes in precipitation) for hypothetical scenarios to assess the effects of groundwater withdrawals and precipitation on water budgets and levels in Big Marine Lake, Snail Lake

  12. Evaluation of Xylella fastidiosa genetic diversity by fAFPL markers Diversidade genética de Xylella fastidiosa avaliada por marcadores fAFPL

    Directory of Open Access Journals (Sweden)

    Luciano Takeshi Kishi

    2008-03-01

    ética entre isolados da bactéria foi detectada da por métodos culturais e moleculares, embora pouco se conheça acerca das relações genéticas de isolados brasileiros obtidos de citros e cafeeiro. Este trabalho teve por objetivo verificar, através de marcadores moleculares fAFLP a existência de diversidade genética e as relações filogenéticas estabelecidas pelos isolados das bactérias brasileiras e estrangeiras. Estes marcadores foram selecionados por sua alta reproducibilidade e por ser de uso comum para tipagem e classificação bacteriana. Os resultados obtidos mostraram que os isolados brasileiros apresentam diversidade genética e que os isolados deste estudo agruparam-se de acordo com o hospedeiro e origem geográfica, a saber, citros-cafeeiro, temécula-videira-amoreira e ameixeira-elmo.

  13. Biogeochemical characterization of the Cointzio reservoir (Morelia, Mexico) and identification of a watershed-dependent cycling of nutrients

    Science.gov (United States)

    Némery, J.; Alvarado, R.; Gratiot, N.; Duvert, C.; Mahé, F.; Duwig, C.; Bonnet, M.; Prat, C.; Esteves, M.

    2009-12-01

    (June to October) bring a high amount of suspended sediments (up to 50g/L) that transport nutrients such as particulate P. Despite the high turbidity level of the reservoir, chlorophyll a concentrations appear important (70 µg/L during the dry season) especially in the first five meters of the water column. The phytoplankton community is dominated by Euglenophyta and Cyanobacteria groups typical of eutrophic waters. This study is the first complete biogeochemical survey of the Cointzio watershed. Results acquired will be used in a 3D biogeochemical model ELMO (Bonnet and Wessen, 2001) with the objective of providing a quantitative and update analysis of the water quality. The model already reproduced thermal stratification but furthers runs are needed to calibrate the biogeochemical modules and provide an efficient tool to reservoir’s managers.

  14. Mammal inventories for eight National Parks in the Southern Colorado Plateau Network

    Science.gov (United States)

    Bogan, Michael A.; Geluso, Keith; Haymond, Shauna; Valdez, Ernest W.

    2007-01-01

    Historically, the Colorado Plateau has been the subject of many geological and biological explorations. J. W. Powell explored and mapped the canyon country of the Colorado River in 1869 (Powell 1961). C. H. Merriam, V. Bailey, M. Cary, and other employees of the Bureau of Biological Survey conducted biological explorations of the area in the late 1800s. In recent times, researchers such as S. D. Durrant (1952), Durrant and Robinson (1962), D. M. Armstrong (1972), J. S. Findley et al. (1975), D. F. Hoff meister (1986), and J. Fitzgerald et al. (1994) have made considerable contributions to our understanding of the fauna of the Colorado Plateau. Despite earlier efforts, biological details on many regions of the plateau have remained insufficiently explored. In an effort to gather valuable biological information, the National Park Service (NPS) initiated a nationwide program to inventory vascular plants and vertebrates on NPS lands (Stuart 2000). The U.S. Geological Survey, Fort Collins Science Center, Arid Lands Field Station became a cooperator on this effort in 2001, when we began mammalian inventories on five parks within the NPS Southern Colorado Plateau Network (SCPN): Aztec Ruins National Monument (AZRU), El Morro National Monument (ELMO), Petroglyph National Monument (PETR), Salinas Pueblo Missions National Monument (SAPU), and Yucca House National Monument (YUHO). Existing baseline data on mammalian occurrences in these parks varied from very sparse to moderate, with little information available for most parks. In most cases, information was insufficient to assess the status of species of local concern. A final report on inventory efforts on these five parks was submitted in February 2004 (Bogan et al. 2004). In 2003, biologists from the Arid Lands Field Station began work on three additional parks in the SCPN: Bandelier National Monument (BAND), Chaco Culture National Historical Park (CHCU), and El Malpaís National Monument (ELMA). The primary emphasis at

  15. Programa de Pós-Graduação em Geologia - Teses Defendidas 1998 - Doutorado - Instituto de Geociências - Universidade Federal do Rio de Janeiro

    Directory of Open Access Journals (Sweden)

    1998-01-01

    representam elevação da fugacidade de CO2 no sistema: 2 forsterita + 2 H2O + CO2 + serpentina + magnesita [6] 4 enstatita + H2O + CO2 = antofilita + magnesita [7] Antofilita acicular ou em rosetas foram formadas sob condições de metamorfismo estático. Clorita e talco se formaram em conseqüência do metamorfismo retrógrado: 3 talco = 3 antofilita + 4 quartzo + 4 H2O [8] 7 serpentina + 10 SiO2 = 3 antofilita + 11 H2O [9] O Complexo Morro das Almas é similar à intrusão Muskox, no que diz respeito a ordem de cristalização dos minerais cumulus (olivina-ortopiroxênio-clinopiroxênioplagioclásio, mas difere no conteúdo de enxofre. Com relação aos aspectos econômicos, o Complexo Morro das Almas apresenta baixo potencial para PGE, devido ao baixo conteúdo de enxofre, conforme ausência total de sulfetos, subordinadas camadas de cromititos e drástica escassez de clinopiroxênio e plagioclásio, sugerindo fracionamento de pequena monta. Nome: Maria da Conceição de Moraes Coutinho Beltrão Título: Ensaio de Arqueologia: Uma Abordagem Transdiciplinar Orientador: Elmo da Silva Amador Resumo: Apontaram-se nesta tese algumas mudanças no campo da Paleontologia Humana em outros continentes para justificar achados em sítios arqueológicos brasileiros, em três estados distintos: São Paulo, Bahia e Rio de Janeiro. No estado de São Paulo, no município de Rio Claro, utilizaram-se, no sítio Alice Boër, 122 Anuário do Instituto de Geociências - UFRJ Volume 21 / 1998 os métodos estratigráficos, C14 (Carbono 14, TL (Termoluminescência, tipologia comparada, além do método de escavação escolhido. Os estudos em Alice Boër, iniciados na década de 60, permitiram que se datasse, pela primeira vez em 1973, pelo método absoluto do C14, um terraço pleistocênico na bacia do Paraná. Abaixo do terraço existe uma praia fóssil e sob ela o leito antigo do rio, contendo artefatos. Com base em várias avaliações calculou-se que os artefatos aí depositados seriam do